WorldWideScience

Sample records for human engineering program

  1. Human Factors Engineering Program Review Model

    Science.gov (United States)

    2004-02-01

    AA NUREG -0711,Rev. 2 Human Factors Engineering Program Review Model 20081009191 I i m To] Bi U.S. Nuclear Regulatory Commission Office of...Material As of November 1999, you may electronically access NUREG -series publications and other NRC records at NRC’s Public Electronic Reading Room at...http://www.nrc.qov/readinq-rm.html. Publicly released records include, to name a few, NUREG -series publications; Federal Register notices; applicant

  2. Human factors engineering program review model

    Energy Technology Data Exchange (ETDEWEB)

    1994-07-01

    The staff of the Nuclear Regulatory Commission is performing nuclear power plant design certification reviews based on a design process plan that describes the human factors engineering (HFE) program elements that are necessary and sufficient to develop an acceptable detailed design specification and an acceptable implemented design. There are two principal reasons for this approach. First, the initial design certification applications submitted for staff review did not include detailed design information. Second, since human performance literature and industry experiences have shown that many significant human factors issues arise early in the design process, review of the design process activities and results is important to the evaluation of an overall design. However, current regulations and guidance documents do not address the criteria for design process review. Therefore, the HFE Program Review Model (HFE PRM) was developed as a basis for performing design certification reviews that include design process evaluations as well as review of the final design. A central tenet of the HFE PRM is that the HFE aspects of the plant should be developed, designed, and evaluated on the basis of a structured top-down system analysis using accepted HFE principles. The HFE PRM consists of ten component elements. Each element in divided into four sections: Background, Objective, Applicant Submittals, and Review Criteria. This report describes the development of the HFE PRM and gives a detailed description of each HFE review element.

  3. Human factors engineering plan for reviewing nuclear plant modernization programs

    Energy Technology Data Exchange (ETDEWEB)

    O' Hara, John; Higgins, James [Brookhaven National Laboratory, Upton, NY (United States)

    2004-12-01

    The Swedish Nuclear Power Inspectorate reviews the human factors engineering (HFE) aspects of nuclear power plants (NPPs) involved in the modernization of the plant systems and control rooms. The purpose of a HFE review is to help ensure personnel and public safety by verifying that accepted HFE practices and guidelines are incorporated into the program and nuclear power plant design. Such a review helps to ensure the HFE aspects of an NPP are developed, designed, and evaluated on the basis of a structured top-down system analysis using accepted HFE principles. The review addresses eleven HFE elements: HFE Program Management, Operating Experience Review, Functional Requirements Analysis and Allocation, Task Analysis, Staffing, Human Reliability Analysis, Human-System Interface Design, Procedure Development, Training Program Development, Human Factors Verification and Validation, and Design Implementation.

  4. Human Research Program Space Human Factors Engineering (SHFE) Standing Review Panel (SRP)

    Science.gov (United States)

    Wichansky, Anna; Badler, Norman; Butler, Keith; Cummings, Mary; DeLucia, Patricia; Endsley, Mica; Scholtz, Jean

    2009-01-01

    The Space Human Factors Engineering (SHFE) Standing Review Panel (SRP) evaluated 22 gaps and 39 tasks in the three risk areas assigned to the SHFE Project. The area where tasks were best designed to close the gaps and the fewest gaps were left out was the Risk of Reduced Safety and Efficiency dire to Inadequate Design of Vehicle, Environment, Tools or Equipment. The areas where there were more issues with gaps and tasks, including poor or inadequate fit of tasks to gaps and missing gaps, were Risk of Errors due to Poor Task Design and Risk of Error due to Inadequate Information. One risk, the Risk of Errors due to Inappropriate Levels of Trust in Automation, should be added. If astronauts trust automation too much in areas where it should not be trusted, but rather tempered with human judgment and decision making, they will incur errors. Conversely, if they do not trust automation when it should be trusted, as in cases where it can sense aspects of the environment such as radiation levels or distances in space, they will also incur errors. This will be a larger risk when astronauts are less able to rely on human mission control experts and are out of touch, far away, and on their own. The SRP also identified 11 new gaps and five new tasks. Although the SRP had an extremely large quantity of reading material prior to and during the meeting, we still did not feel we had an overview of the activities and tasks the astronauts would be performing in exploration missions. Without a detailed task analysis and taxonomy of activities the humans would be engaged in, we felt it was impossible to know whether the gaps and tasks were really sufficient to insure human safety, performance, and comfort in the exploration missions. The SRP had difficulty evaluating many of the gaps and tasks that were not as quantitative as those related to concrete physical danger such as excessive noise and vibration. Often the research tasks for cognitive risks that accompany poor task or

  5. Information Presentation: Human Research Program - Space Human Factors and Habitability, Space Human Factors Engineering Project

    Science.gov (United States)

    Holden, Kristina L.; Sandor, Aniko; Thompson, Shelby G.; Kaiser, Mary K.; McCann, Robert S.; Begault, D. R.; Adelstein, B. D.; Beutter, B. R.; Wenzel, E. M.; Godfroy, M.; Stone, L. S.

    2010-01-01

    The goal of the Information Presentation Directed Research Project (DRP) is to address design questions related to the presentation of information to the crew. The major areas of work, or subtasks, within this DRP are: 1) Displays, 2) Controls, 3) Electronic Procedures and Fault Management, and 4) Human Performance Modeling. This DRP is a collaborative effort between researchers atJohnson Space Center and Ames Research Center. T

  6. Programming Google App Engine

    CERN Document Server

    Sanderson, Dan

    2010-01-01

    As one of today's cloud computing services, Google App Engine does more than provide access to a large system of servers. It also offers you a simple model for building applications that scale automatically to accommodate millions of users. With Programming Google App Engine, you'll get expert practical guidance that will help you make the best use of this powerful platform. Google engineer Dan Sanderson shows you how to design your applications for scalability, including ways to perform common development tasks using App Engine's APIs and scalable services. You'll learn about App Engine's a

  7. Small engine technology programs

    Science.gov (United States)

    Niedzwiecki, Richard W.

    1990-01-01

    Described here is the small engine technology program being sponsored at the Lewis Research Center. Small gas turbine research is aimed at general aviation, commuter aircraft, rotorcraft, and cruise missile applications. The Rotary Engine program is aimed at supplying fuel flexible, fuel efficient technology to the general aviation industry, but also has applications to other missions. The Automotive Gas Turbine (AGT) and Heavy-Duty Diesel Transport Technology (HDTT) programs are sponsored by DOE. The Compound Cycle Engine program is sponsored by the Army. All of the programs are aimed towards highly efficient engine cycles, very efficient components, and the use of high temperature structural ceramics. This research tends to be generic in nature and has broad applications. The HDTT, rotary technology, and the compound cycle programs are all examining approaches to minimum heat rejection, or 'adiabatic' systems employing advanced materials. The AGT program is also directed towards ceramics application to gas turbine hot section components. Turbomachinery advances in the gas turbine programs will benefit advanced turbochargers and turbocompounders for the intermittent combustion systems, and the fundamental understandings and analytical codes developed in the research and technology programs will be directly applicable to the system projects.

  8. A Human Resource Development Program for Information Technology Engineers using Project-Based Learning

    Directory of Open Access Journals (Sweden)

    Minoru Nakayama

    2012-11-01

    Full Text Available This paper reports the case of an educational practice and evaluation of team learning using project-based learning to develop Information Technology engineers. This program aims to develop the competencies of engineers, such as their communication skills, problem solving within teams, and other abilities. Its subject is the “Upper Process” of Information Technology systems development. To determine the feasibility of the course, it was conducted at a computer college. The team’s products and team learning activities were evaluated using rubrics and self evaluation inventories, and learning performance was discussed. Also, the evaluation of the learning management system affected the learning activity.

  9. Heavy Truck Engine Program

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, Christopher

    2009-01-08

    The Heavy Duty Truck Engine Program at Cummins embodied three significant development phases. All phases of work strove to demonstrate a high level of diesel engine efficiency in the face of increasingly stringent emission requirements. Concurrently, aftertreatment system development and refinement was pursued in support of these efficiency demonstrations. The program's first phase focused on the demonstration in-vehicle of a high level of heavy duty diesel engine efficiency (45% Brake Thermal Efficiency) at a typical cruise condition while achieving composite emissions results which met the 2004 U.S. EPA legislated standards. With a combination of engine combustion calibration tuning and the development and application of Urea-based SCR and particulate aftertreatment, these demonstrations were successfully performed by Q4 of 2002. The second phase of the program directed efforts towards an in-vehicle demonstration of an engine system capable of meeting 2007 U.S. EPA legislated emissions requirements while achieving 45% Brake Thermal Efficiency at cruise conditions. Through further combustion optimization, the refinement of Cummins Cooled EGR architecture, the application of a high pressure common rail fuel system and the incorporation of optimized engine parasitics, Cummins Inc. successfully demonstrated these deliverables in Q2 of 2004. The program's final phase set a stretch goal of demonstrating 50% Brake Thermal Efficiency from a heavy duty diesel engine system capable of meeting 2010 U.S. EPA legislated emissions requirements. Cummins chose to pursue this goal through further combustion development and refinement of the Cooled EGR system architecture and also applied a Rankine cycle Waste Heat Recovery technique to convert otherwise wasted thermal energy to useful power. The engine and heat recovery system was demonstrated to achieve 50% Brake Thermal Efficiency while operating at a torque peak condition in second quarter, 2006. The 50% efficient

  10. The First Development of Human Factors Engineering Requirements for Application to Ground Task Design for a NASA Flight Program

    Science.gov (United States)

    Dischinger, H. Charles, Jr.; Stambolian, Damon B.; Miller, Darcy H.

    2008-01-01

    The National Aeronautics and Space Administration has long applied standards-derived human engineering requirements to the development of hardware and software for use by astronauts while in flight. The most important source of these requirements has been NASA-STD-3000. While there have been several ground systems human engineering requirements documents, none has been applicable to the flight system as handled at NASA's launch facility at Kennedy Space Center. At the time of the development of previous human launch systems, there were other considerations that were deemed more important than developing worksites for ground crews; e.g., hardware development schedule and vehicle performance. However, experience with these systems has shown that failure to design for ground tasks has resulted in launch schedule delays, ground operations that are more costly than they might be, and threats to flight safety. As the Agency begins the development of new systems to return humans to the moon, the new Constellation Program is addressing this issue with a new set of human engineering requirements. Among these requirements is a subset that will apply to the design of the flight components and that is intended to assure ground crew success in vehicle assembly and maintenance tasks. These requirements address worksite design for usability and for ground crew safety.

  11. Accreditation of Industrial Engineering Programs.

    Science.gov (United States)

    Brooks, George H.

    The guidelines used in the accreditation of industrial engineering programs are discussed. Changes that have taken place in engineering curriculum are described, along with the philosophy of educators in formulating industrial engineering program requirements in the areas of faculty, facilities, curriculum, administration, and scholastic work.…

  12. Software Engineering for Human Spaceflight

    Science.gov (United States)

    Fredrickson, Steven E.

    2014-01-01

    The Spacecraft Software Engineering Branch of NASA Johnson Space Center (JSC) provides world-class products, leadership, and technical expertise in software engineering, processes, technology, and systems management for human spaceflight. The branch contributes to major NASA programs (e.g. ISS, MPCV/Orion) with in-house software development and prime contractor oversight, and maintains the JSC Engineering Directorate CMMI rating for flight software development. Software engineering teams work with hardware developers, mission planners, and system operators to integrate flight vehicles, habitats, robotics, and other spacecraft elements. They seek to infuse automation and autonomy into missions, and apply new technologies to flight processor and computational architectures. This presentation will provide an overview of key software-related projects, software methodologies and tools, and technology pursuits of interest to the JSC Spacecraft Software Engineering Branch.

  13. Reservoir Engineering Management Program

    Energy Technology Data Exchange (ETDEWEB)

    Howard, J.H.; Schwarz, W.J.

    1977-12-14

    The Reservoir Engineering Management Program being conducted at Lawrence Berkeley Laboratory includes two major tasks: 1) the continuation of support to geothermal reservoir engineering related work, started under the NSF-RANN program and transferred to ERDA at the time of its formation; 2) the development and subsequent implementation of a broad plan for support of research in topics related to the exploitation of geothermal reservoirs. This plan is now known as the GREMP plan. Both the NSF-RANN legacies and GREMP are in direct support of the DOE/DGE mission in general and the goals of the Resource and Technology/Resource Exploitation and Assessment Branch in particular. These goals are to determine the magnitude and distribution of geothermal resources and reduce risk in their exploitation through improved understanding of generically different reservoir types. These goals are to be accomplished by: 1) the creation of a large data base about geothermal reservoirs, 2) improved tools and methods for gathering data on geothermal reservoirs, and 3) modeling of reservoirs and utilization options. The NSF legacies are more research and training oriented, and the GREMP is geared primarily to the practical development of the geothermal reservoirs. 2 tabs., 3 figs.

  14. Medical devices and human engineering

    CERN Document Server

    Bronzino, Joseph D

    2014-01-01

    Known as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering.Medical Devices and Human Engineering, the second volume of the handbook, presents material from respected scientists with diverse backgrounds in biomedical sensors, medical instrumentation and devices, human performance engineering, rehabilitation engineering, and clinical engineering.More than three doze

  15. Automotive Stirling engine development program

    Science.gov (United States)

    Ernst, W.; Richey, A.; Farrell, R.; Riecke, G.; Smith, G.; Howarth, R.; Cronin, M.; Simetkosky, M.; Meacher, J.

    1986-01-01

    This is the ninth Semiannual Technical Progress Report prepared under the Automotive Stirling Engine Development Program. It covers the twenty-eighth and twenty-ninth quarters of activity after award of the contract. Quarterly Technical Progress Reports related program activities from the first through the thirteenth quarters; thereafter, reporting was changed to a Semiannual format. This report summarizes the study of higher-power kinematic Stirling engines for transportation use, development testing of Mod I Stirling engines, and component development activities. Component development testing included successful conical fuel nozzle testing and functional checkout of Mod II controls and auxiliaries on Mod I engine test beds. Overall program philosophy is outlined and data and test results are presented.

  16. Human Reliability Program Overview

    Energy Technology Data Exchange (ETDEWEB)

    Bodin, Michael

    2012-09-25

    This presentation covers the high points of the Human Reliability Program, including certification/decertification, critical positions, due process, organizational structure, program components, personnel security, an overview of the US DOE reliability program, retirees and academia, and security program integration.

  17. Program For Engineering Electrical Connections

    Science.gov (United States)

    Billitti, Joseph W.

    1990-01-01

    DFACS is interactive multiuser computer-aided-engineering software tool for system-level electrical integration and cabling engineering. Purpose of program to provide engineering community with centralized data base for putting in and gaining access to data on functional definition of system, details of end-circuit pinouts in systems and subsystems, and data on wiring harnesses. Objective, to provide instantaneous single point of interchange of information, thus avoiding error-prone, time-consuming, and costly shuttling of data along multiple paths. Designed to operate on DEC VAX mini or micro computer using Version 5.0/03 of INGRES.

  18. High Efficiency Engine Technologies Program

    Energy Technology Data Exchange (ETDEWEB)

    Rich Kruiswyk

    2010-07-13

    Caterpillar's Product Development and Global Technology Division carried out a research program on waste heat recovery with support from DOE (Department of Energy) and the DOE National Energy Technology Laboratory. The objective of the program was to develop a new air management and exhaust energy recovery system that would demonstrate a minimum 10% improvement in thermal efficiency over a base heavy-duty on-highway diesel truck engine. The base engine for this program was a 2007 C15 15.2L series-turbocharged on-highway truck engine with a LPL (low-pressure loop) exhaust recirculation system. The focus of the program was on the development of high efficiency turbomachinery and a high efficiency turbocompound waste heat recovery system. The focus of each area of development was as follows: (1) For turbine stages, the focus was on investigation and development of technologies that would improve on-engine exhaust energy utilization compared to the conventional radial turbines in widespread use today. (2) For compressor stages, the focus was on investigating compressor wheel design parameters beyond the range typically utilized in production, to determine the potential efficiency benefits thereof. (3) For turbocompound, the focus was on the development of a robust bearing system that would provide higher bearing efficiencies compared to systems used in turbocompound power turbines in production. None of the turbocharger technologies investigated involved addition of moving parts, actuators, or exotic materials, thereby increasing the likelihood of a favorable cost-value tradeoff for each technology. And the turbocompound system requires less hardware addition than competing bottoming cycle technologies, making it a more attractive solution from a cost and packaging standpoint. Main outcomes of the program are as follows: (1) Two turbine technologies that demonstrated up to 6% improvement in turbine efficiency on gas stand and 1-3% improvement in thermal efficiency

  19. High Efficiency Engine Technologies Program

    Energy Technology Data Exchange (ETDEWEB)

    Rich Kruiswyk

    2010-07-13

    Caterpillar's Product Development and Global Technology Division carried out a research program on waste heat recovery with support from DOE (Department of Energy) and the DOE National Energy Technology Laboratory. The objective of the program was to develop a new air management and exhaust energy recovery system that would demonstrate a minimum 10% improvement in thermal efficiency over a base heavy-duty on-highway diesel truck engine. The base engine for this program was a 2007 C15 15.2L series-turbocharged on-highway truck engine with a LPL (low-pressure loop) exhaust recirculation system. The focus of the program was on the development of high efficiency turbomachinery and a high efficiency turbocompound waste heat recovery system. The focus of each area of development was as follows: (1) For turbine stages, the focus was on investigation and development of technologies that would improve on-engine exhaust energy utilization compared to the conventional radial turbines in widespread use today. (2) For compressor stages, the focus was on investigating compressor wheel design parameters beyond the range typically utilized in production, to determine the potential efficiency benefits thereof. (3) For turbocompound, the focus was on the development of a robust bearing system that would provide higher bearing efficiencies compared to systems used in turbocompound power turbines in production. None of the turbocharger technologies investigated involved addition of moving parts, actuators, or exotic materials, thereby increasing the likelihood of a favorable cost-value tradeoff for each technology. And the turbocompound system requires less hardware addition than competing bottoming cycle technologies, making it a more attractive solution from a cost and packaging standpoint. Main outcomes of the program are as follows: (1) Two turbine technologies that demonstrated up to 6% improvement in turbine efficiency on gas stand and 1-3% improvement in thermal efficiency

  20. Human Factors Interface with Systems Engineering for NASA Human Spaceflights

    Science.gov (United States)

    Wong, Douglas T.

    2009-01-01

    This paper summarizes the past and present successes of the Habitability and Human Factors Branch (HHFB) at NASA Johnson Space Center s Space Life Sciences Directorate (SLSD) in including the Human-As-A-System (HAAS) model in many NASA programs and what steps to be taken to integrate the Human-Centered Design Philosophy (HCDP) into NASA s Systems Engineering (SE) process. The HAAS model stresses systems are ultimately designed for the humans; the humans should therefore be considered as a system within the systems. Therefore, the model places strong emphasis on human factors engineering. Since 1987, the HHFB has been engaging with many major NASA programs with much success. The HHFB helped create the NASA Standard 3000 (a human factors engineering practice guide) and the Human Systems Integration Requirements document. These efforts resulted in the HAAS model being included in many NASA programs. As an example, the HAAS model has been successfully introduced into the programmatic and systems engineering structures of the International Space Station Program (ISSP). Success in the ISSP caused other NASA programs to recognize the importance of the HAAS concept. Also due to this success, the HHFB helped update NASA s Systems Engineering Handbook in December 2007 to include HAAS as a recommended practice. Nonetheless, the HAAS model has yet to become an integral part of the NASA SE process. Besides continuing in integrating HAAS into current and future NASA programs, the HHFB will investigate incorporating the Human-Centered Design Philosophy (HCDP) into the NASA SE Handbook. The HCDP goes further than the HAAS model by emphasizing a holistic and iterative human-centered systems design concept.

  1. Human productivity program definition

    Science.gov (United States)

    Cramer, D. B.

    1985-01-01

    The optimization of human productivity on the space station within the existing resources and operational constraints is the aim of the Human Productivity Program. The conceptual objectives of the program are as follows: (1) to identify long lead technology; (2) to identify responsibility for work elements; (3) to coordinate the development of crew facilities and activities; and (4) to lay the foundation for a cost effective approach to improving human productivity. Human productivity work elements are also described and examples are presented.

  2. Sodium Heat Engine Development Program

    Energy Technology Data Exchange (ETDEWEB)

    Singh, J.P.; Kupperman, D.S.; Majumdar, S.; Dorris, S.; Gopalsami, N.; Dieckman, S.L.; Jaross, R.A.; Johnson, D.L.; Gregar, J.S.; Poeppel, R.B.; Raptis, A.C.; Valentin, R.A.

    1992-01-01

    The Sodium Heat Engine (SHE) is an efficient thermoelectric conversion device which directly generates electricity from a thermally regenerative electrochemical cell that relies on the unique conduction properties of {beta}{double prime}-alumina solid electrolyte (BASE). Laboratory models of a variety of SHE devices have demonstrated the feasibility and efficiency of the system, engineering development of large prototype devices has been slowed by a series of materials and fabrication problems. Failure of the electrolyte tubes has been a recurring problem and a number of possible causes have been postulated. To address these issues, a two-phase engineering development program was undertaken. This report summarizes the final results of the first phase of the program, which included extensive materials characterization activities, a study of applicable nondestructive evaluation methods, an investigation of possible stress states that would contribute to fracture, and certain operational issues associated with the electromagnetic pumps used in the SHE prototype. Mechanical and microstructural evaluation of commercially obtained BASE tubes revealed that they should be adequate for SHE applications and that sodium exposure produced no appreciable deleterious strength effects. Processing activities to produce a more uniform and smaller grain size for the BASE tubes were completed using isostatic pressing, extrusion, and slip casting. Green tubes were sintered by conventional and microwave plasma methods. Of particular interest is the residual stress state in the BASE tubes, and both analysis and nondestructive evaluation methods were employed to evaluate these stresses. X-ray and neutron diffraction experiments were performed to determine the bulk residual stresses in commercially fabricated BASE tubes; however, tube-to-tube variations and variations among the various methods employed did not allow formulation of a definitive definition of the as-fabricated stress state.

  3. Gasoline Engine Mechanics. Florida Vocational Program Guide.

    Science.gov (United States)

    University of South Florida, Tampa. Dept. of Adult and Vocational Education.

    This vocational program guide is intended to assist in the organization, operation, and evaluation of a program in gasoline engine mechanics in school districts, area vocational centers, and community colleges. The following topics are covered: job duties of small-engine mechanics; program content (curriculum framework and student performance…

  4. The AGINAO Self-Programming Engine

    Science.gov (United States)

    Skaba, Wojciech

    2013-01-01

    The AGINAO is a project to create a human-level artificial general intelligence system (HL AGI) embodied in the Aldebaran Robotics' NAO humanoid robot. The dynamical and open-ended cognitive engine of the robot is represented by an embedded and multi-threaded control program, that is self-crafted rather than hand-crafted, and is executed on a simulated Universal Turing Machine (UTM). The actual structure of the cognitive engine emerges as a result of placing the robot in a natural preschool-like environment and running a core start-up system that executes self-programming of the cognitive layer on top of the core layer. The data from the robot's sensory devices supplies the training samples for the machine learning methods, while the commands sent to actuators enable testing hypotheses and getting a feedback. The individual self-created subroutines are supposed to reflect the patterns and concepts of the real world, while the overall program structure reflects the spatial and temporal hierarchy of the world dependencies. This paper focuses on the details of the self-programming approach, limiting the discussion of the applied cognitive architecture to a necessary minimum.

  5. A Program on Biochemical and Biomedical Engineering.

    Science.gov (United States)

    San, Ka-Yiu; McIntire, Larry V.

    1989-01-01

    Presents an introduction to the Biochemical and Biomedical Engineering program at Rice University. Describes the development of the academic and enhancement programs, including organizational structure and research project titles. (YP)

  6. A Program on Biochemical and Biomedical Engineering.

    Science.gov (United States)

    San, Ka-Yiu; McIntire, Larry V.

    1989-01-01

    Presents an introduction to the Biochemical and Biomedical Engineering program at Rice University. Describes the development of the academic and enhancement programs, including organizational structure and research project titles. (YP)

  7. Genome engineering in human cells.

    Science.gov (United States)

    Song, Minjung; Kim, Young-Hoon; Kim, Jin-Soo; Kim, Hyongbum

    2014-01-01

    Genome editing in human cells is of great value in research, medicine, and biotechnology. Programmable nucleases including zinc-finger nucleases, transcription activator-like effector nucleases, and RNA-guided engineered nucleases recognize a specific target sequence and make a double-strand break at that site, which can result in gene disruption, gene insertion, gene correction, or chromosomal rearrangements. The target sequence complexities of these programmable nucleases are higher than 3.2 mega base pairs, the size of the haploid human genome. Here, we briefly introduce the structure of the human genome and the characteristics of each programmable nuclease, and review their applications in human cells including pluripotent stem cells. In addition, we discuss various delivery methods for nucleases, programmable nickases, and enrichment of gene-edited human cells, all of which facilitate efficient and precise genome editing in human cells.

  8. Building Effective Minority Programs in Engineering Education.

    Science.gov (United States)

    National Academy of Sciences - National Research Council, Washington, DC. Assembly of Engineering.

    Two surveys were conducted to identify the essential characteristics of minority engineering programs and to provide summaries of ongoing minority programs in a broad sampling of engineering schools. The first surveyed colleges with the largest minority enrollments, including the 6 traditionally Black schools and 45 predominantly white schools.…

  9. Tissue Engineered Human Skin Equivalents

    Directory of Open Access Journals (Sweden)

    Zheng Zhang

    2012-01-01

    Full Text Available Human skin not only serves as an important barrier against the penetration of exogenous substances into the body, but also provides a potential avenue for the transport of functional active drugs/reagents/ingredients into the skin (topical delivery and/or the body (transdermal delivery. In the past three decades, research and development in human skin equivalents have advanced in parallel with those in tissue engineering and regenerative medicine. The human skin equivalents are used commercially as clinical skin substitutes and as models for permeation and toxicity screening. Several academic laboratories have developed their own human skin equivalent models and applied these models for studying skin permeation, corrosivity and irritation, compound toxicity, biochemistry, metabolism and cellular pharmacology. Various aspects of the state of the art of human skin equivalents are reviewed and discussed.

  10. Space Life-Support Engineering Program

    Science.gov (United States)

    Seagrave, Richard C. (Principal Investigator)

    1995-01-01

    This report covers the seventeen months of work performed under an extended one year NASA University Grant awarded to Iowa State University to perform research on topics relating to the development of closed-loop long-term life support systems with the initial principal focus on space water management. In the first phase of the program, investigators from chemistry and chemical engineering with demonstrated expertise in systems analysis, thermodynamics, analytical chemistry and instrumentation, performed research and development in two major related areas; the development of low-cost, accurate, and durable sensors for trace chemical and biological species, and the development of unsteady-state simulation packages for use in the development and optimization of control systems for life support systems. In the second year of the program, emphasis was redirected towards concentrating on the development of dynamic simulation techniques and software and on performing a thermodynamic systems analysis, centered on availability or energy analysis, in an effort to begin optimizing the systems needed for water purification. The third year of the program, the subject of this report, was devoted to the analysis of the water balance for the interaction between humans and the life support system during space flight and exercise, to analysis of the cardiopulmonary systems of humans during space flight, and to analysis of entropy production during operation of the air recovery system during space flight.

  11. Hydrogen hybrid vehicle engine development: Experimental program

    Energy Technology Data Exchange (ETDEWEB)

    Van Blarigan, P. [Sandia National Lab., Livermore, CA (United States)

    1995-09-01

    A hydrogen fueled engine is being developed specifically for the auxiliary power unit (APU) in a series type hybrid vehicle. Hydrogen is different from other internal combustion (IC) engine fuels, and hybrid vehicle IC engine requirements are different from those of other IC vehicle engines. Together these differences will allow a new engine design based on first principles that will maximize thermal efficiency while minimizing principal emissions. The experimental program is proceeding in four steps: (1) Demonstration of the emissions and the indicated thermal efficiency capability of a standard CLR research engine modified for higher compression ratios and hydrogen fueled operation. (2) Design and test a new combustion chamber geometry for an existing single cylinder research engine, in an attempt to improve on the baseline indicated thermal efficiency of the CLR engine. (3) Design and build, in conjunction with an industrial collaborator, a new full scale research engine designed to maximize brake thermal efficiency. Include a full complement of combustion diagnostics. (4) Incorporate all of the knowledge thus obtained in the design and fabrication, by an industrial collaborator, of the hydrogen fueled engine for the hybrid vehicle power train illustrator. Results of the CLR baseline engine testing are presented, as well as preliminary data from the new combustion chamber engine. The CLR data confirm the low NOx produced by lean operation. The preliminary indicated thermal efficiency data from the new combustion chamber design engine show an improvement relative to the CLR engine. Comparison with previous high compression engine results shows reasonable agreement.

  12. Hydrogen engine development: Experimental program

    Energy Technology Data Exchange (ETDEWEB)

    Van Blarigan, P. [Sandia National Lab., Livermore, CA (United States)

    1996-10-01

    In the continuing development of a hydrogen fueled IC engine optimized for application to a generator set or hybrid vehicle, experiments were performed at Sandia National Laboratories on two engine configurations. The intent is to maximize thermal efficiency while complying with strict emissions standards. The initial investigation was conducted utilizing a spark ignited 0.491 liter single cylinder Onan engine and has progressed to a spark ignited 0.850 liter modified for single cylinder operation Perkins engine. Both combustion chamber geometries were {open_quotes}pancake{close_quotes} shaped and achieved a compression ratio of 14:1. The engines were operated under premixed conditions. The results demonstrate that both engines can comply with the California Air Resources Board`s proposed Equivalent Zero Emission Vehicle standards for NO{sub x} during operation at an equivalence ratio of 0.4. The Onan engine achieved an indicated thermal efficiency of 43% at 1800 RPM, as determined by integration of the pressure-volume relationships. Initial experiments with the larger displacement Perkins engine have realized a gain, relative to the Onan engine, in indicated thermal efficiency of 2% at 1800 RPM, and 15% at 1200 RPM.

  13. CCSD Well Logging Engineering Program

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    This paper introduces briefly the tasks and characteristics of China Continent Science Drilling (CCSD) Well Logging Engineering, the logging methods measured with CCSD, the quality control of original logging information, the logging plan of CCSD, the logging engineering management of CCSD,the logging interpretation and the results and reports made with CCSD.

  14. Programming Surface Chemistry with Engineered Cells.

    Science.gov (United States)

    Zhang, Ruihua; Heyde, Keith C; Scott, Felicia Y; Paek, Sung-Ho; Ruder, Warren C

    2016-09-16

    We have developed synthetic gene networks that enable engineered cells to selectively program surface chemistry. E. coli were engineered to upregulate biotin synthase, and therefore biotin synthesis, upon biochemical induction. Additionally, two different functionalized surfaces were developed that utilized binding between biotin and streptavidin to regulate enzyme assembly on programmable surfaces. When combined, the interactions between engineered cells and surfaces demonstrated that synthetic biology can be used to engineer cells that selectively control and modify molecular assembly by exploiting surface chemistry. Our system is highly modular and has the potential to influence fields ranging from tissue engineering to drug development and delivery.

  15. Engineering Design Education Program for Graduate School

    Science.gov (United States)

    Ohbuchi, Yoshifumi; Iida, Haruhiko

    The new educational methods of engineering design have attempted to improve mechanical engineering education for graduate students in a way of the collaboration in education of engineer and designer. The education program is based on the lecture and practical exercises concerning the product design, and has engineering themes and design process themes, i.e. project management, QFD, TRIZ, robust design (Taguchi method) , ergonomics, usability, marketing, conception etc. At final exercise, all students were able to design new product related to their own research theme by applying learned knowledge and techniques. By the method of engineering design education, we have confirmed that graduate students are able to experience technological and creative interest.

  16. Human Factors Analysis in Software Engineering

    Institute of Scientific and Technical Information of China (English)

    Xu Ren-zuo; Ma Ruo-feng; Liu Li-na; Xiong Zhong-wei

    2004-01-01

    The general human factors analysis analyzes human functions, effects and influence in a system. But in a narrow sense, it analyzes human influence upon the reliability of a system, it includes traditional human reliability analysis, human error analysis, man-machine interface analysis, human character analysis, and others. A software development project in software engineering is successful or not to be completely determined by human factors. In this paper, we discuss the human factors intensions, declare the importance of human factors analysis for software engineering by listed some instances. At last, we probe preliminarily into the mentality that a practitioner in software engineering should possess.

  17. Human Reliability Program Workshop

    Energy Technology Data Exchange (ETDEWEB)

    Landers, John; Rogers, Erin; Gerke, Gretchen

    2014-05-18

    A Human Reliability Program (HRP) is designed to protect national security as well as worker and public safety by continuously evaluating the reliability of those who have access to sensitive materials, facilities, and programs. Some elements of a site HRP include systematic (1) supervisory reviews, (2) medical and psychological assessments, (3) management evaluations, (4) personnel security reviews, and (4) training of HRP staff and critical positions. Over the years of implementing an HRP, the Department of Energy (DOE) has faced various challenges and overcome obstacles. During this 4-day activity, participants will examine programs that mitigate threats to nuclear security and the insider threat to include HRP, Nuclear Security Culture (NSC) Enhancement, and Employee Assistance Programs. The focus will be to develop an understanding of the need for a systematic HRP and to discuss challenges and best practices associated with mitigating the insider threat.

  18. MSU Adopts Business-Engineering Program

    Science.gov (United States)

    Chemical and Engineering News, 1973

    1973-01-01

    A program leading to a bachelor of science degree is discussed which combines a required core of engineering studies with application studies in one of four fields: industrial design, business, communication, or social sciences. (DF)

  19. National Hispanic Bilingual Engineering Program (NHBEP)

    Energy Technology Data Exchange (ETDEWEB)

    Cruz, M.

    2000-10-31

    This report describes program goals, activities, processes, benefits for the profession of engineering and for the project participants, coordination, and impact of NHBEP throughout the three years of implementation.

  20. Application of Statistics in Engineering Technology Programs

    Science.gov (United States)

    Zhan, Wei; Fink, Rainer; Fang, Alex

    2010-01-01

    Statistics is a critical tool for robustness analysis, measurement system error analysis, test data analysis, probabilistic risk assessment, and many other fields in the engineering world. Traditionally, however, statistics is not extensively used in undergraduate engineering technology (ET) programs, resulting in a major disconnect from industry…

  1. Programming and engineering biological networks.

    Science.gov (United States)

    Chin, Jason W

    2006-08-01

    Synthetic biology aims to build new functions in living organisms. Recent work has addressed the creation of synthetic epigenetic switches in mammalian cells and synthetic intracellular communication. Fundamentally new, and potentially scaleable, modes of gene regulation have been created that enable expansion of the scope of synthetic circuits. Increasingly sophisticated models of gene regulation that include stochastic effects are beginning to predict the behaviour of small synthetic networks. Overall, these advances suggest that a combination of molecular engineering and systems engineering should allow the creation of living matter capable of performing many useful and novel functions.

  2. Local control stations: Human engineering issues and insights

    Energy Technology Data Exchange (ETDEWEB)

    Brown, W.S.; Higgins, J.C.; O`Hara, J.M. [Brookhaven National Lab., Upton, NY (United States)

    1994-09-01

    The objective of this research project was to evaluate current human engineering at local control stations (LCSs) in nuclear power plants, and to identify good human engineering practices relevant to the design of these operator interfaces. General literature and reports of operating experience were reviewed to determine the extent and type of human engineering deficiencies at LCSs in nuclear power plants. In-plant assessments were made of human engineering at single-function as well as multifunction LCSs. Besides confirming the existence of human engineering deficiencies at LCSs, the in-plant assessments provided information about the human engineering upgrades that have been made at nuclear power plants. Upgrades were typically the result of any of three influences regulatory activity, broad industry initiatives such as INPO, and specific in-plant programs (e.g. activities related to training). It is concluded that the quality of LCSs is quite variable and might be improved if there were greater awareness of good practices and existing human engineering guidance relevant to these operator interfaces, which is available from a variety of sources. To make such human engineering guidance more readily accessible, guidelines were compiled from such sources and included in the report as an appendix.

  3. Evolution of the Systems Engineering Education Development (SEED) Program at NASA Goddard Space Flight Center

    Science.gov (United States)

    Bagg, Thomas C., III; Brumfield, Mark D.; Jamison, Donald E.; Granata, Raymond L.; Casey, Carolyn A.; Heller, Stuart

    2003-01-01

    The Systems Engineering Education Development (SEED) Program at NASA Goddard Space Flight Center develops systems engineers from existing discipline engineers. The program has evolved significantly since the report to INCOSE in 2003. This paper describes the SEED Program as it is now, outlines the changes over the last year, discusses current status and results, and shows the value of human systems and leadership skills for practicing systems engineers.

  4. Register of Environmental Engineering Undergraduate Programs.

    Science.gov (United States)

    Aulenbach, Donald B., Ed.

    This document outlines undergraduate programs leading to degrees in environmental engineering from 22 schools across the country. The register includes general information on the school and program as well as specific information on admission requirements, degree requirements, course work, and faculty and student data. A copy of the questionnaire…

  5. Repository-Based Software Engineering Program: Working Program Management Plan

    Science.gov (United States)

    1993-01-01

    Repository-Based Software Engineering Program (RBSE) is a National Aeronautics and Space Administration (NASA) sponsored program dedicated to introducing and supporting common, effective approaches to software engineering practices. The process of conceiving, designing, building, and maintaining software systems by using existing software assets that are stored in a specialized operational reuse library or repository, accessible to system designers, is the foundation of the program. In addition to operating a software repository, RBSE promotes (1) software engineering technology transfer, (2) academic and instructional support of reuse programs, (3) the use of common software engineering standards and practices, (4) software reuse technology research, and (5) interoperability between reuse libraries. This Program Management Plan (PMP) is intended to communicate program goals and objectives, describe major work areas, and define a management report and control process. This process will assist the Program Manager, University of Houston at Clear Lake (UHCL) in tracking work progress and describing major program activities to NASA management. The goal of this PMP is to make managing the RBSE program a relatively easy process that improves the work of all team members. The PMP describes work areas addressed and work efforts being accomplished by the program; however, it is not intended as a complete description of the program. Its focus is on providing management tools and management processes for monitoring, evaluating, and administering the program; and it includes schedules for charting milestones and deliveries of program products. The PMP was developed by soliciting and obtaining guidance from appropriate program participants, analyzing program management guidance, and reviewing related program management documents.

  6. English Curriculum in Global Engineer Education Program

    Science.gov (United States)

    Furuya, Okitsugu; Bright, Olga; Saika, Takashi

    The educational goal of the Faculty of Global Engineering (FGE) of the Kogakuin University is to prepare the graduates to be global engineers. The requirements for the global engineer are multifold; having the basic and advanced engineering knowledge together with the international communication skills and experiences. The curriculum at the Kogakuin University has been designed and developed over the last ten years. Among others, “Communication Skills for Global Engineers (CSGE) ” and “Engineering Clinic Program (ECP) ” play essential roles, the former providing the students with the communication skills and the latter engineering design skills. An impact on the students studying together with foreign students is so strong and immeasurable. The English they learned in Japan does not work as well as they thought it would, and the attitude of the foreign students toward studying they observe is a kind of “shocking” . The student who joined ECP abroad/CSGE abroad come back to Japan as a very inspired and different person, the first step becoming a global engineer. In this paper, various aspects of the program will be discussed with the problem areas to be further improved being identified.

  7. Emeritus Scientists, Mathematicians and Engineers (ESME) program

    Energy Technology Data Exchange (ETDEWEB)

    Sharlin, H.I.

    1992-09-01

    The Emeritus Scientists, Mathematicians and Engineers (ESME) program matches retired scientists and engineers with wide experience with elementary school children in order to fuel the children's natural curiosity about the world in which they live. The long-range goal is to encourage students to maintain the high level of mathematical and science capability that they exhibit at an early age by introducing them to the fun and excitement of the world of scientific investigation and engineering problem solving. Components of the ESME program are the emeriti, established teacher-emeriti teams that work to produce a unit of 6 class hours of demonstration or hands-on experiments, and the encounter by students with the world of science/engineering through the classroom sessions and a field trip to a nearby plant or laboratory.

  8. Human Genome Program

    Energy Technology Data Exchange (ETDEWEB)

    1993-01-01

    The DOE Human Genome program has grown tremendously, as shown by the marked increase in the number of genome-funded projects since the last workshop held in 1991. The abstracts in this book describe the genome research of DOE-funded grantees and contractors and invited guests, and all projects are represented at the workshop by posters. The 3-day meeting includes plenary sessions on ethical, legal, and social issues pertaining to the availability of genetic data; sequencing techniques, informatics support; and chromosome and cDNA mapping and sequencing.

  9. Human Genome Program

    Energy Technology Data Exchange (ETDEWEB)

    1993-01-01

    The DOE Human Genome program has grown tremendously, as shown by the marked increase in the number of genome-funded projects since the last workshop held in 1991. The abstracts in this book describe the genome research of DOE-funded grantees and contractors and invited guests, and all projects are represented at the workshop by posters. The 3-day meeting includes plenary sessions on ethical, legal, and social issues pertaining to the availability of genetic data; sequencing techniques, informatics support; and chromosome and cDNA mapping and sequencing.

  10. Human Flesh Search Engine and Online Privacy.

    Science.gov (United States)

    Zhang, Yang; Gao, Hong

    2016-04-01

    Human flesh search engine can be a double-edged sword, bringing convenience on the one hand and leading to infringement of personal privacy on the other hand. This paper discusses the ethical problems brought about by the human flesh search engine, as well as possible solutions.

  11. Space Life Support Engineering Program

    Science.gov (United States)

    Seagrave, Richard C.

    1993-01-01

    This report covers the second year of research relating to the development of closed-loop long-term life support systems. Emphasis was directed toward concentrating on the development of dynamic simulation techniques and software and on performing a thermodynamic systems analysis in an effort to begin optimizing the system needed for water purification. Four appendices are attached. The first covers the ASPEN modeling of the closed loop Environmental Control Life Support System (ECLSS) and its thermodynamic analysis. The second is a report on the dynamic model development for water regulation in humans. The third regards the development of an interactive computer-based model for determining exercise limitations. The fourth attachment is an estimate of the second law thermodynamic efficiency of the various units comprising an ECLSS.

  12. Space Transportation Engine Program (STEP), phase B

    Science.gov (United States)

    1990-10-01

    The Space Transportation Engine Program (STEP) Phase 2 effort includes preliminary design and activities plan preparation that will allow smooth and time transition into a Prototype Phase and then into Phases 3, 4, and 5. A Concurrent Engineering approach using Total Quality Management (TQM) techniques, is being applied to define an oxygen-hydrogen engine. The baseline from Phase 1/1' studies was used as a point of departure for trade studies and analyses. Existing STME system models are being enhanced as more detailed module/component characteristics are determined. Preliminary designs for the open expander, closed expander, and gas generator cycles were prepared, and recommendations for cycle selection made at the Design Concept Review (DCR). As a result of July '90 DCR, and information subsequently supplied to the Technical Review Team, a gas generator cycle was selected. Results of the various Advanced Development Programs (ADP's) for the Advanced Launch Systems (ALS) were contributive to this effort. An active vehicle integration effort is supplying the NASA, Air Force, and vehicle contractors with engine parameters and data, and flowing down appropriate vehicle requirements. Engine design and analysis trade studies are being documented in a data base that was developed and is being used to organize information. To date, seventy four trade studies were input to the data base.

  13. Master of Engineering Energy Systems Engineering Program: Smart Campus Energy Systems Demonstration DE-SC0005523

    Energy Technology Data Exchange (ETDEWEB)

    Dodge, Martha [Lehigh Univ., Bethlehem, PA (United States); Coulter, John [Lehigh Univ., Bethlehem, PA (United States)

    2014-09-25

    Program Purpose and Position: The mission of the Master of Engineering in Energy Systems Engineering program is to invigorate the pipeline of new engineering graduates interested in energy oriented careers and thus produce a new generation of technical leaders for the energy and power industries. Over the next decade, nearly 50% of the skilled workers and technical leaders in the gas and electric utility industries will retire -- a much larger void than the current available and qualified professionals could fill [CEWD, 2012 survey]. The Masters of Engineering in Energy System Engineering program provides an opportunity for cross-discipline education for graduates interested in a career in the energy industry. It focuses on electric power and the challenges and opportunities to develop a sustainable, reliable and resilient system that meets human needs in an increasingly sustainable manner through the use of environmentally sound energy resources and delivery. Both graduates and employers benefit from a well-trained professional workforce that is ready to hit the road running and be immediately productive in meeting these challenges, through this innovative and unique program.

  14. Bridging Resilience Engineering and Human Reliability Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Ronald L. Boring

    2010-06-01

    There has been strong interest in the new and emerging field called resilience engineering. This field has been quick to align itself with many existing safety disciplines, but it has also distanced itself from the field of human reliability analysis. To date, the discussion has been somewhat one-sided, with much discussion about the new insights afforded by resilience engineering. This paper presents an attempt to address resilience engineering from the perspective of human reliability analysis (HRA). It is argued that HRA shares much in common with resilience engineering and that, in fact, it can help strengthen nascent ideas in resilience engineering. This paper seeks to clarify and ultimately refute the arguments that have served to divide HRA and resilience engineering.

  15. Advanced interdisciplinary undergraduate program: light engineering

    Science.gov (United States)

    Bakholdin, Alexey; Bougrov, Vladislav; Voznesenskaya, Anna; Ezhova, Kseniia

    2016-09-01

    The undergraduate educational program "Light Engineering" of an advanced level of studies is focused on development of scientific learning outcomes and training of professionals, whose activities are in the interdisciplinary fields of Optical engineering and Technical physics. The program gives practical experience in transmission, reception, storage, processing and displaying information using opto-electronic devices, automation of optical systems design, computer image modeling, automated quality control and characterization of optical devices. The program is implemented in accordance with Educational standards of the ITMO University. The specific features of the Program is practice- and problem-based learning implemented by engaging students to perform research and projects, internships at the enterprises and in leading Russian and international research educational centers. The modular structure of the Program and a significant proportion of variable disciplines provide the concept of individual learning for each student. Learning outcomes of the program's graduates include theoretical knowledge and skills in natural science and core professional disciplines, deep knowledge of modern computer technologies, research expertise, design skills, optical and optoelectronic systems and devices.

  16. Geochemical engineering and materials program plan

    Energy Technology Data Exchange (ETDEWEB)

    None

    1982-08-01

    The Department of Energy (DOE) was designated as lead agency in discharging the overall legislative mandate for federal R&D to assist the private sector in developing appropriate technology for exploiting geothermal energy resources. The Geochemical Engineering and Materials (GEM) Program was conceived, as part of DOE'S overall strategy, to address specific and plant-wide problems and uncertainties in the use of materials and in geochemical engineering. This program assists industry in the conduct of long-term,high-risk R&D needed to overcome the significant technical and economic GEM-related obstacles faced by developers and potential developers of this alternative energy source. The program focuses on: (1) Increasing the knowledge about the properties of materials and their performance under geothermal energy system conditions; (2) Developing and utilizing more reliable and/or cost-effective materials than previously available; and (3) Developing a greater understanding of and control over geochemical processes during fluid production and transport, energy conversion, and waste management. As a stand-alone program and as support to other DOE geothermal technology development programs, the GEM Program contributes to the feasibility of designing and operating efficient, reliable, and safe fluid handling and energy conversion systems.

  17. Automatic program generation: future of software engineering

    Energy Technology Data Exchange (ETDEWEB)

    Robinson, J.H.

    1979-01-01

    At this moment software development is still more of an art than an engineering discipline. Each piece of software is lovingly engineered, nurtured, and presented to the world as a tribute to the writer's skill. When will this change. When will the craftsmanship be removed and the programs be turned out like so many automobiles from an assembly line. Sooner or later it will happen: economic necessities will demand it. With the advent of cheap microcomputers and ever more powerful supercomputers doubling capacity, much more software must be produced. The choices are to double the number of programers, double the efficiency of each programer, or find a way to produce the needed software automatically. Producing software automatically is the only logical choice. How will automatic programing come about. Some of the preliminary actions which need to be done and are being done are to encourage programer plagiarism of existing software through public library mechanisms, produce well understood packages such as compiler automatically, develop languages capable of producing software as output, and learn enough about the whole process of programing to be able to automate it. Clearly, the emphasis must not be on efficiency or size, since ever larger and faster hardware is coming.

  18. Engineering drawing field verification program. Revision 3

    Energy Technology Data Exchange (ETDEWEB)

    Ulk, P.F.

    1994-10-12

    Safe, efficient operation of waste tank farm facilities is dependent in part upon the availability of accurate, up-to-date plant drawings. Accurate plant drawings are also required in support of facility upgrades and future engineering remediation projects. This supporting document establishes the procedure for performing a visual field verification of engineering drawings, the degree of visual observation being performed and documenting the results. A copy of the drawing attesting to the degree of visual observation will be paginated into the released Engineering Change Notice (ECN) documenting the field verification for future retrieval and reference. All waste tank farm essential and support drawings within the scope of this program will be converted from manual to computer aided drafting (CAD) drawings. A permanent reference to the field verification status will be placed along the right border of the CAD-converted drawing, referencing the revision level, at which the visual verification was performed and documented.

  19. Human Factors Engineering Aspects of Modifications in Control Room Modernization

    Energy Technology Data Exchange (ETDEWEB)

    Hugo, Jacques; Clefton, Gordon; Joe, Jeffrey

    2017-06-01

    This report describes the basic aspects of control room modernization projects in the U.S. nuclear industry and the need for supplementary guidance on the integration of human factors considerations into the licensing and regulatory aspects of digital upgrades. The report pays specific attention to the integration of principles described in NUREG-0711 (Human Factors Engineering Program Review Model) and how supplementary guidance can help to raise general awareness in the industry regarding the complexities of control room modernization projects created by many interdependent regulations, standards and guidelines. The report also describes how human factors engineering principles and methods provided by various resources and international standards can help in navigating through the process of licensing digital upgrades. In particular, the integration of human factors engineering guidance and requirements into the process of licensing digital upgrades can help reduce uncertainty related to development of technical bases for digital upgrades that will avoid the introduction of new failure modes.

  20. Repository-based software engineering program

    Science.gov (United States)

    Wilson, James

    1992-01-01

    The activities performed during September 1992 in support of Tasks 01 and 02 of the Repository-Based Software Engineering Program are outlined. The recommendations and implementation strategy defined at the September 9-10 meeting of the Reuse Acquisition Action Team (RAAT) are attached along with the viewgraphs and reference information presented at the Institute for Defense Analyses brief on legal and patent issues related to software reuse.

  1. Human genome. 1993 Program report

    Energy Technology Data Exchange (ETDEWEB)

    1994-03-01

    The purpose of this report is to update the Human Genome 1991-92 Program Report and provide new information on the DOE genome program to researchers, program managers, other government agencies, and the interested public. This FY 1993 supplement includes abstracts of 60 new or renewed projects and listings of 112 continuing and 28 completed projects. These two reports, taken together, present the most complete published view of the DOE Human Genome Program through FY 1993. Research is progressing rapidly toward 15-year goals of mapping and sequencing the DNA of each of the 24 different human chromosomes.

  2. NASA Space Human Factors Program

    Science.gov (United States)

    1992-01-01

    This booklet briefly and succinctly treats 23 topics of particular interest to the NASA Space Human Factors Program. Most articles are by different authors who are mainly NASA Johnson or NASA Ames personnel. Representative topics covered include mental workload and performance in space, light effects on Circadian rhythms, human sleep, human reasoning, microgravity effects and automation and crew performance.

  3. 130 FEMINISM AND HUMAN GENETIC ENGINEERING: A ...

    African Journals Online (AJOL)

    Ike Odimegwu

    Abstract. Human genetic in the area of Bio-ethics is a new, rapidly advancing. Science. ... Human genetic engineering, a recent one in medical science and practice, is one ..... The Church on Cloning and Stem Cell Research. The teaching of ...

  4. Human Factors Engineering. Student Supplement,

    Science.gov (United States)

    1981-08-01

    Psychologists as Division 21 of the APA . It seems fitting, now that engineering psychology has been recognized as a viable entity, that we examine this new...34INFIC 161ST SCALE ___________ P CIUUIOIC POP40 3 SMTCPWONSI OARIA C0" NORMA . IN. AIDS AMU Ls". PLA0D 11aw Lu". FILM PACK CLR so. RAW MOTIVE LIS mm’ 7

  5. Can your software engineer program your PLC?

    Science.gov (United States)

    Borrowman, Alastair J.; Taylor, Philip

    2016-07-01

    The use of Programmable Logic Controllers (PLCs) in the control of large physics experiments is ubiquitous1, 2, 3. The programming of these controllers is normally the domain of engineers with a background in electronics, this paper introduces PLC program development from the software engineer's perspective. PLC programs provide the link between control software running on PC architecture systems and physical hardware controlled and monitored by digital and analog signals. The higher-level software running on the PC is typically responsible for accepting operator input and from this deciding when and how hardware connected to the PLC is controlled. The PLC accepts demands from the PC, considers the current state of its connected hardware and if correct to do so (based upon interlocks or other constraints) adjusts its hardware output signals appropriately for the PC's demands. A published ICD (Interface Control Document) defines the PLC memory locations available to be written and read by the PC to control and monitor the hardware. Historically the method of programming PLCs has been ladder diagrams that closely resemble circuit diagrams, however, PLC manufacturers nowadays also provide, and promote, the use of higher-level programming languages4. Based on techniques used in the development of high-level PC software to control PLCs for multiple telescopes, this paper examines the development of PLC programs to operate the hardware of a medical cyclotron beamline controlled from a PC using the Experimental Physics and Industrial Control System (EPICS), which is also widely used in telescope control5, 6, 7. The PLC used is the new generation Siemens S7-1200 programmed using Siemens Pascal based Structured Control Language (SCL), which is their implementation of Structured Text (ST). The approach described is that from a software engineer's perspective, utilising Siemens Totally Integrated Automation (TIA) Portal integrated development environment (IDE) to create

  6. Human Research Program

    Data.gov (United States)

    National Aeronautics and Space Administration — Strategically, the HRP conducts research and technology development that: 1) enables the development or modification of Agency-level human health and performance...

  7. Analysis of Engineering Content within Technology Education Programs

    Science.gov (United States)

    Fantz, Todd D.; Katsioloudis, Petros J.

    2011-01-01

    In order to effectively teach engineering, technology teachers need to be taught engineering content, concepts, and related pedagogy. Some researchers posit that technology education programs may not have enough content to prepare technology teachers to teach engineering design. Certain technology teacher education programs have responded by…

  8. Developing Systems Engineering Graduate Programs Aligned to the Body of Knowledge and Curriculum to Advance Systems Engineering (BKCASE (trademark)) Guidelines

    Science.gov (United States)

    2011-06-01

    Developing Systems Engineering Graduate Programs Aligned to the Body of Knowledge and Curriculum to Advance Systems Engineering (BKCASETM...Developing Systems Engineering Graduate Programs Aligned to the Body of Knowledge and Curriculum to Advance Systems Engineering (BKCASETM) Guidelines 5a

  9. Basic Gasoline Engine Mechanics. Florida Vocational Program Guide.

    Science.gov (United States)

    University of South Florida, Tampa. Dept. of Adult and Vocational Education.

    This packet contains a program guide and Career Merit Achievement Plan (Career MAP) for the implementation of a basic gasoline engine mechanics program in Florida secondary and postsecondary schools. The program guide describes the program content and structure, provides a program description, lists job titles under the program, and includes a…

  10. Sustainability in engineering programs in a Portuguese Public University

    Directory of Open Access Journals (Sweden)

    Ciliana Regina Colombo

    Full Text Available Abstract Rethink the interventions, human practices and their effects on the natural environment, for the preservation of life and biodiversity, threatened by the capitalist model of production, consumption and disposal, becomes each day more indispensable. The role of universities as knowledge building space is fundamental for the insertion of the environmental approach (greening in its various fronts (education, research, extension, and management. Following the line of several types of researches about the subject, this paper aims to identify if and how the issue of sustainability (e.g. through Project-Based Learning use is taught in the various engineering programs of a Portuguese Public University. This study was carried out by a documental research based on the programs´ curricula published in the official website of the university. The engineering programs selected included integrated master, master (second cycle and doctorate (third cycle. In this study, it was identified programs that are more focused on sustainability concepts than others, so the programs were classified in three categories: strongest, medium and weakest focus.

  11. Academic program models for undergraduate biomedical engineering.

    Science.gov (United States)

    Krishnan, Shankar M

    2014-01-01

    There is a proliferation of medical devices across the globe for the diagnosis and therapy of diseases. Biomedical engineering (BME) plays a significant role in healthcare and advancing medical technologies thus creating a substantial demand for biomedical engineers at undergraduate and graduate levels. There has been a surge in undergraduate programs due to increasing demands from the biomedical industries to cover many of their segments from bench to bedside. With the requirement of multidisciplinary training within allottable duration, it is indeed a challenge to design a comprehensive standardized undergraduate BME program to suit the needs of educators across the globe. This paper's objective is to describe three major models of undergraduate BME programs and their curricular requirements, with relevant recommendations to be applicable in institutions of higher education located in varied resource settings. Model 1 is based on programs to be offered in large research-intensive universities with multiple focus areas. The focus areas depend on the institution's research expertise and training mission. Model 2 has basic segments similar to those of Model 1, but the focus areas are limited due to resource constraints. In this model, co-op/internship in hospitals or medical companies is included which prepares the graduates for the work place. In Model 3, students are trained to earn an Associate Degree in the initial two years and they are trained for two more years to be BME's or BME Technologists. This model is well suited for the resource-poor countries. All three models must be designed to meet applicable accreditation requirements. The challenges in designing undergraduate BME programs include manpower, facility and funding resource requirements and time constraints. Each academic institution has to carefully analyze its short term and long term requirements. In conclusion, three models for BME programs are described based on large universities, colleges, and

  12. Teaching Programming to Engineers-The Choice Language

    OpenAIRE

    Morris, A.S.

    1981-01-01

    The paper examines the merits of the major languages presently available for teaching computer programming to engineering students. Consideration of the ultimate application of programming by engineers is given prominence in this evaluation, which it is hoped will fill a gap in the information presently available to planners of engineering courses. Recommendations about the best language are made from engineering considerations and offer an alternative to the much less application-orientated ...

  13. Reformulating General Engineering and Biological Systems Engineering Programs at Virginia Tech

    Science.gov (United States)

    Lohani, Vinod K.; Wolfe, Mary Leigh; Wildman, Terry; Mallikarjunan, Kumar; Connor, Jeffrey

    2011-01-01

    In 2004, a group of engineering and education faculty at Virginia Tech received a major curriculum reform and engineering education research grant under the department-level reform (DLR) program of the NSF. This DLR project laid the foundation of sponsored research in engineering education in the Department of Engineering Education. The DLR…

  14. Geochemical engineering problem identification and program description. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Crane, C.H.; Kenkeremath, D.C.

    1981-05-01

    The Geochemical Engineering Program has as its goal the improvement of geochemical fluid management techniques. This document presents the strategy and status of the Geochemical Engineering Program. The magnitude and scope of geochemical-related problems constraining geothermal industry productivity are described. The goals and objectives of the DGE Geochemical Engineering Program are defined. The rationale and strategy of the program are described. The structure, priorities, funding, and management of specific elements within the program are delineated, and the status of the overall program is presented.

  15. Data systems and computer science: Software Engineering Program

    Science.gov (United States)

    Zygielbaum, Arthur I.

    1991-01-01

    An external review of the Integrated Technology Plan for the Civil Space Program is presented. This review is specifically concerned with the Software Engineering Program. The goals of the Software Engineering Program are as follows: (1) improve NASA's ability to manage development, operation, and maintenance of complex software systems; (2) decrease NASA's cost and risk in engineering complex software systems; and (3) provide technology to assure safety and reliability of software in mission critical applications.

  16. Teaching of GIS in Mexico's Engineering Programs

    Science.gov (United States)

    Domínguez C., Miguel A.; Ventura R., Eusebio

    2008-05-01

    Application of Geographical Information Systems (GIS) in Mexico for the solution of territorial-based problems has been widely extended in the last decade. However, teaching and learning have been mainly based on short training courses or workshops focused on software knowledge acquiring, but without the basic background of geographical sciences that allow the understanding of fundamentals principles related to geographical information management, theory, methods of analysis and modeling, as well as the study of interactions between the different processes across the land surface. In spite of the explosive growth of the GIS use, the teaching of fundamental principles still is limited to formal courses taught in universities. The goal of this study is to analyze the role of GIS technology as generator of territorial knowledge, its evolution and use by companies, as well as its presence in curricular plans of study in the different engineering programs in Mexico.

  17. Graduate Education Program of Design and Integration Capability at Department of Mechanical Engineering, Graduate School of Engineering, Osaka University

    Science.gov (United States)

    Fujita, Kikuo

    Department of Mechanical Engineering, Graduate School of Engineering, Osaka University is now developing “Graduate Education Program of Design and Integration Capability” under the MEXT's scheme entitled “Initiatives for Attractive Education in Graduate Schools”. Maturation of society and life, globalization of manufacturing industry, latest demands of human's welfare have changed the meaning of design from functional ensureance to value creation. This requests graduate education of mechanical engineering to turn its definition over both synthesis and analysis and to learning and communication capabilities beyond knowledge itself. With recognizing such a background, the program aims to reform the education curriculum of mechanical engineering by introducing a product design subject which integrates design methodology education and project-based learning over industry- sponsored design problems, several graduate-level fundamental subjects, and the depth area system in which elective subjects are categorized into several areas based on their specialty. This paper describes the objectives, undertakings, promises, etc. of the program.

  18. Human Factors in Nuclear Power Engineering in Polish Conditions

    Directory of Open Access Journals (Sweden)

    Agnieszka Kaczmarek-Kacprzak

    2014-09-01

    Full Text Available The paper “Human factors in nuclear power engineering in Polish conditions” focuses on analysis of dynamics of preparing Polish society to build fi rst nuclear power plant in XXI century in Poland. Authors compare experience from constructing nuclear power plant Sizewell B (Great Britain and Sizewell C, which is in preparation phase with polish nuclear power program. Paper includes aspects e.g. of creating nuclear safety culture and social opinion about investment. Human factors in nuclear power engineering are as well important as relevant economical and technical factors, but very often negligible. In Poland where history about Czarnobyl is still alive, and social opinion is created on emotions after accident in Fukushima, human factors are crucial and should be under comprehensive consideration.

  19. Automotive Stirling Engine Development Program Mod I Stirling engine development

    Science.gov (United States)

    Simetkosky, M. A.

    1983-01-01

    The development of the Mod I 4-cylinder automotive Stirling engine is discussed and illustrated with drawings, block diagrams, photographs, and graphs and tables of preliminary test data. The engine and its drive, cold-engine, hot-engine, external-heat, air/fuel, power-control, electronic-control, and auxiliary systems are characterized. Performance results from a total of 1900 h of tests on 4 prototype engines include average maximum efficiency (at 2000 rpm) 34.5 percent and maximum output power 54.4 kW. The modifications introduced in an upgraded version of the Mod I are explained; this engine has maximum efficiency 40.4 percent and maximum power output 69.2 kW.

  20. Documentation of the Benson Diesel Engine Simulation Program

    Science.gov (United States)

    Vangerpen, Jon

    1988-01-01

    This report documents the Benson Diesel Engine Simulation Program and explains how it can be used to predict the performance of diesel engines. The program was obtained from the Garrett Turbine Engine Company but has been extensively modified since. The program is a thermodynamic simulation of the diesel engine cycle which uses a single zone combustion model. It can be used to predict the effect of changes in engine design and operating parameters such as valve timing, speed and boost pressure. The most significan change made to this program is the addition of a more detailed heat transfer model to predict metal part temperatures. This report contains a description of the sub-models used in the Benson program, a description of the input parameters and sample program runs.

  1. Humanities Program: Critique and Rationale.

    Science.gov (United States)

    Pinar, William Frederick

    The psychological impact of schooling is examined within the context of a new school of British psychoanalytic thought. It is concluded that schooling is maddening, in the sense used by Laing, Cooper, and others. A rationale for a sane humanities program is established consisting of two components: the nuclear and the cortical. The nuclear is the…

  2. Engineering Education Development to Enhance Human Skill in DENSO

    Science.gov (United States)

    Isogai, Emiko; Nuka, Takeji

    Importance of human skills such as communication or instruction capability to their staff members has recently been highlighted in a workplace, due to decreasing opportunity of face-to-face communication between supervisors and their staff, or Instruction capability through OJT (On the Job Training) . Currently, communication skills are being reinforced mainly through OJT at DENSO. Therefore, as part of supplemental support tools, DENSO has established comprehensive engineers training program on off-JT basis for developing human skills, covering from newly employeed enginners up to managerial class since 2003. This paper describes education activities and reports the results.

  3. A Summer Leadership Development Program for Chemical Engineering Students

    Science.gov (United States)

    Simpson, Annie E.; Evans, Greg J.; Reeve, Doug

    2012-01-01

    The Engineering Leaders of Tomorrow Program (LOT) is a comprehensive curricular, co-curricular, extra-curricular leadership development initiative for engineering students. LOT envisions: "an engineering education that is a life-long foundation for transformational leaders and outstanding citizens." Academic courses, co-curricular certificate…

  4. 2014 Space Human Factors Engineering Standing Review Panel

    Science.gov (United States)

    Steinberg, Susan

    2014-01-01

    The 2014 Space Human Factors Engineering (SHFE) Standing Review Panel (from here on referred to as the SRP) participated in a WebEx/teleconference with members of the Space Human Factors and Habitability (SHFH) Element, representatives from the Human Research Program (HRP), the National Space Biomedical Research Institute (NSBRI), and NASA Headquarters on November 17, 2014 (list of participants is in Section XI of this report). The SRP reviewed the updated research plans for the Risk of Incompatible Vehicle/Habitat Design (HAB Risk) and the Risk of Performance Errors Due to Training Deficiencies (Train Risk). The SRP also received a status update on the Risk of Inadequate Critical Task Design (Task Risk), the Risk of Inadequate Design of Human and Automation/Robotic Integration (HARI Risk), and the Risk of Inadequate Human-Computer Interaction (HCI Risk).

  5. Retaining minorities in engineering: Assessment of a program prototype

    Science.gov (United States)

    Good, Jennifer Marie (Phillips)

    Program assessment is an essential part of healthy program development. Assessment should include multiple considerations, dimensions, and outcomes that match the program's objectives. As a newly formed retention program, the Auburn University Minority Engineering Program, designed to help pre-engineering minority students make the transition into their freshman year of university studies, incorporated evaluation and assessment into all three components of the program (the interactive learning laboratory, critical-thinking workshops, and Sunday-evening tutorials) from the program's inception. If students successfully adapted to the university environment and the demands of the pre-engineering course of study, then retention of minority students in the College of Engineering should improve. Data were gathered on the students involved in the various program components. Students who entered the Minority Engineering Program were pre- and posttested on three standardized subtests (critical thinking, mathematics, and science reasoning) of the Collegiate Assessment of Academic Proficiency. The first-quarter grade-point averages of the students were also gathered to compare their grades to freshman students in previous quarters within the College of Engineering. Qualitative data were also gathered on this same group of students. An analysis of the data revealed that student achievement is affected by involvement in the Minority Engineering Program. Specifically, the first quarter grade point averages of students involved in the program exceeded those of their peers in earlier years of study prior to the program's existence. In addition, mathematics and science reasoning scores on standardized tests increased pre- to postintervention. Comments collected in journals and files also demonstrated use of critical-thinking and problem-solving skills employed by the students. Recommendations for alterations of the program were made based on the outcome of the program evaluation

  6. The AIBS In Yugoslavia: Programs in Biomedical Engineering

    Science.gov (United States)

    Thompson, Mary-Frances

    1978-01-01

    Programs in biomedical engineering have been developing worldwide since World War II. This article describes a multidisciplinary program which operates in Yugoslavia through a cooperative effort between that county and the AIBS. A major problem has been the slowness with which hospitals accept the concept of biomedical engineering. (MA)

  7. Impact of Engineering Ambassador Programs on Student Development

    Science.gov (United States)

    Anagnos, Thalia; Lyman-Holt, Alicia; Marin-Artieda, Claudia; Momsen, Ellen

    2014-01-01

    This study highlights the positive impact of participation in an engineering ambassador program on students from two universities: Oregon State University which is a large public university in a college town with a 13% minority student body, and Howard University, a medium sized private university with a relatively small engineering program in an…

  8. Integration of Social Sciences and Humanities into Mechanical Engineering Curriculum

    Directory of Open Access Journals (Sweden)

    Nikša Dubreta

    2014-04-01

    Full Text Available Article deals with ways in which social sciences and humanities have been integrated from the 1980s to the present day into curriculum of Faculty of Mechanical Engineering and Naval Architecture at University of Zagreb, Croatia. After a brief review and summary of selected research and theoretical contributions to the subject theme, a specific research setting is indicated and contextualized. Elements of socio-historical approach are established primarily through analysis of corresponding documents: curriculums from the 1980s, 1990s and 2000s and from key documents on strategic development of the Faculty. It is stressed that social sciences and humanities topics are continually represented in mechanical engineering study program as legitimate, but separate unit, poorly integrated in the main engineering courses. Together with more or less expressed orientation toward micro-social and micro-economical issues in industry and business, it points to the main features in continuity of establishing the field of social sciences and humanities. Finally, it is shown that chances to widen and enrich aforementioned field are in close relation to the character of engineering and its social contextualization expressed in a key Faculty’s strategic documents.

  9. Highway Safety Program Manual: Volume 13: Traffic Engineering Services.

    Science.gov (United States)

    National Highway Traffic Safety Administration (DOT), Washington, DC.

    Volume 13 of the 19-volume Highway Safety Program Manual (which provides guidance to State and local governments on preferred highway safety practices) focuses on traffic engineering services. The introduction outlines the purposes and objectives of Highway Safety Program Standard 13 and the Highway Safety Program Manual. Program development and…

  10. The human dimension of program evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Vine, E.L.

    1993-05-01

    Social science issues play an important role in the evaluation of demand-side management (DSM) programs. In the very early years of DSM program evaluation in the United States, there was a fair amount of social science research applied to the behavioral aspects of energy efficiency. Since the mid-1980s, however, there has been a heavy emphasis on impact evaluation, technical measurement, and engineering methodologies. Although some have articulated the need to integrate behavioral research into energy evaluation, most emphasis has tended to center on the technical/engineering aspects. Increasingly, however, the realization is growing that it is necessary to integrate important behavioral variables into impact evaluation techniques. In addition, it is being further recognized that behavioral research questions are central to a number of critical evaluation issues: e.g., design of samples for evaluation studies, net energy savings, self-selection bias, free riders and free drivers, persistence of energy savings, process evaluation, and market impact evaluation. Finally, it is increasingly being realized that the utilization of evaluation results relies heavily on behavioral factors. Social science researchers should be poised to expect a greatly expanded role of behavioral research in evaluation. As new techniques are developed and perfected, as the results of impact evaluations become more abundant, and as the gap between technical energy savings potential and realized savings becomes more visible, research regarding the ``human dimension`` of program evaluation will be crucial. This paper provides an overview of the human dimension of program evaluation and focuses on key evaluation issues in demand-side management which will require the use of social science research for addressing these issues.

  11. Rapid Prototyping and the Human Factors Engineering Process

    Science.gov (United States)

    2016-08-29

    Rapid prototyping and the human factors • • engineering process David Beevis* and Gaetan St Denist *Senior Human Factors Engineer , Defence and...factors engineering analyses. Therefore, an investigation of the use of the V APS virtual prototyping system was carried out in five organizations. The...factors engineering (HFE) process re- commended for the development of human-machine systems is based on a series of increasin¥ly detailed analyses of

  12. CDIO Projects in Civil Engineering Study Program at DTU

    DEFF Research Database (Denmark)

    Krogsbøll, Anette; Simonsen, Claus; Christensen, Jørgen Erik

    2011-01-01

    or a design build project on each of the first four semesters. In this paper the four projects in the civil engineering study program are described along with a brief description of the entire study program. The aim is to provide additional information and documentation to accompany an exposition where......In 2008 all Bachelor of engineering study programs at the Technical University of Denmark (DTU) have been adopted to the “Conceive – Design – Implement – Operate” approach. As part of the necessary changes it was decided that all seven study programs should have a cross disciplinary project...... students present their projects. Learning outcomes, training and assessment of personal, professional and social engineering skills are described from a project point of view. Progression of engineering skills is discussed from a study program perspective. The interrelation between the various elements...

  13. CDIO Projects in Civil Engineering Study Program at DTU

    DEFF Research Database (Denmark)

    Krogsbøll, Anette; Simonsen, Claus; Christensen, Jørgen Erik

    2011-01-01

    or a design build project on each of the first four semesters. In this paper the four projects in the civil engineering study program are described along with a brief description of the entire study program. The aim is to provide additional information and documentation to accompany an exposition where......In 2008 all Bachelor of engineering study programs at the Technical University of Denmark (DTU) have been adopted to the “Conceive – Design – Implement – Operate” approach. As part of the necessary changes it was decided that all seven study programs should have a cross disciplinary project...... students present their projects. Learning outcomes, training and assessment of personal, professional and social engineering skills are described from a project point of view. Progression of engineering skills is discussed from a study program perspective. The interrelation between the various elements...

  14. Using Pair Programming to Teach CAD Based Engineering Graphics

    Science.gov (United States)

    Leland, Robert P.

    2010-01-01

    Pair programming was introduced into a course in engineering graphics that emphasizes solid modeling using SolidWorks. In pair programming, two students work at a single computer, and periodically trade off roles as driver (hands on the keyboard and mouse) and navigator (discuss strategy and design issues). Pair programming was used in a design…

  15. Register of Environmental Engineering Graduate Programs. Third Edition.

    Science.gov (United States)

    Klosky, Jane C., Ed.

    This document summarizes the status of environmental engineering programs in the United States and Canada today. The volume contains information on over 70 university programs. Each listing gives a two- or three-paragraph description of the program, institution, etc. In addition, information can be found on admission requirements, degree…

  16. Biomedical Engineering: A Compendium of Research Training Programs.

    Science.gov (United States)

    National Inst. of General Medical Sciences (NIH), Bethesda, MD.

    This document was prepared to provide a comprehensive view of the programs in biomedical engineering in existence in 1969. These programs are supported by the National Institute of General Medical Sciences and are located at 18 universities. This compendium provides information as to the intent and content of these programs from data provided by…

  17. Using Pair Programming to Teach CAD Based Engineering Graphics

    Science.gov (United States)

    Leland, Robert P.

    2010-01-01

    Pair programming was introduced into a course in engineering graphics that emphasizes solid modeling using SolidWorks. In pair programming, two students work at a single computer, and periodically trade off roles as driver (hands on the keyboard and mouse) and navigator (discuss strategy and design issues). Pair programming was used in a design…

  18. Human subject research for engineers a practical guide

    CERN Document Server

    de Winter, Joost C F

    2017-01-01

    This Brief introduces engineers to the main principles in ethics, research design, statistics, and publishing of human subject research. In recent years, engineering has become strongly connected to disciplines such as biology, medicine, and psychology. Often, engineers (and engineering students) are expected to perform human subject research. Typical human subject research topics conducted by engineers include human-computer interaction (e.g., evaluating the usability of software), exoskeletons, virtual reality, teleoperation, modelling of human behaviour and decision making (often within the framework of ‘big data’ research), product evaluation, biometrics, behavioural tracking (e.g., of work and travel patterns, or mobile phone use), transport and planning (e.g., an analysis of flows or safety issues), etc. Thus, it can be said that knowledge on how to do human subject research is indispensable for a substantial portion of engineers. Engineers are generally well trained in calculus and mechanics, but m...

  19. Toys for Tots in Your Technology and Engineering Program

    Science.gov (United States)

    Berkeihiser, Mike

    2016-01-01

    Most technology and engineering (T&E) classes are elective, so teachers are always looking for ways to market programs, engage students, and remind administrators and school board members about the good things T&E teachers do with and for kids. In this article, the Unionville High School (PA) Technology and Engineering Department describes…

  20. Teaching Continuum Mechanics in a Mechanical Engineering Program

    Science.gov (United States)

    Liu, Yucheng

    2011-01-01

    This paper introduces a graduate course, continuum mechanics, which is designed for and taught to graduate students in a Mechanical Engineering (ME) program. The significance of continuum mechanics in engineering education is demonstrated and the course structure is described. Methods used in teaching this course such as topics, class…

  1. Teaching Continuum Mechanics in a Mechanical Engineering Program

    Science.gov (United States)

    Liu, Yucheng

    2011-01-01

    This paper introduces a graduate course, continuum mechanics, which is designed for and taught to graduate students in a Mechanical Engineering (ME) program. The significance of continuum mechanics in engineering education is demonstrated and the course structure is described. Methods used in teaching this course such as topics, class…

  2. 77 FR 14766 - Patents for Humanity Program (Formerly Humanitarian Program)

    Science.gov (United States)

    2012-03-13

    ... United States Patent and Trademark Office Patents for Humanity Program (Formerly Humanitarian Program) ACTION: Proposed collection; comment request. SUMMARY: The United States Patent and Trademark Office...- 0066 Patents for Humanity Program comment'' in the subject line of the message. Mail: Susan K....

  3. Human Machine Interface Programming and Testing

    Science.gov (United States)

    Foster, Thomas Garrison

    2013-01-01

    Human Machine Interface (HMI) Programming and Testing is about creating graphical displays to mimic mission critical ground control systems in order to provide NASA engineers with the ability to monitor the health management of these systems in real time. The Health Management System (HMS) is an online interactive human machine interface system that monitors all Kennedy Ground Control Subsystem (KGCS) hardware in the field. The Health Management System is essential to NASA engineers because it allows remote control and monitoring of the health management systems of all the Programmable Logic Controllers (PLC) and associated field devices. KGCS will have equipment installed at the launch pad, Vehicle Assembly Building, Mobile Launcher, as well as the Multi-Purpose Processing Facility. I am designing graphical displays to monitor and control new modules that will be integrated into the HMS. The design of the display screen will closely mimic the appearance and functionality of the actual modules. There are many different field devices used to monitor health management and each device has its own unique set of health management related data, therefore each display must also have its own unique way to display this data. Once the displays are created, the RSLogix5000 application is used to write software that maps all the required data read from the hardware to the graphical display. Once this data is mapped to its corresponding display item, the graphical display and hardware device will be connected through the same network in order to test all possible scenarios and types of data the graphical display was designed to receive. Test Procedures will be written to thoroughly test out the displays and ensure that they are working correctly before being deployed to the field. Additionally, the Kennedy Ground Controls Subsystem's user manual will be updated to explain to the NASA engineers how to use the new module displays.

  4. Global engineering education programs: More than just international experiences

    Science.gov (United States)

    McNeill, Nathan J.

    Engineers in both industry and academia recognize the global nature of the profession. This has lead to calls for engineering students to develop knowledge, skills, and attitudes necessary for success within a global profession. Many institutions are developing globally oriented programs specifically for their engineering students and are eager to know if these programs are helping their students to develop attributes that meet their program objectives, accreditation requirements, and the needs and desires of prospective employers. Administrators of such programs currently lack research data to support the learning objectives they are setting for their programs. This study documented the individual experiences and learning outcomes of students involved in three global education programs for engineering students. The first program provided a portfolio of experiences including foreign language instruction, one semester of study abroad, internships in the U.S. and abroad, and a two-semester global team design project. The second program was a one semester study abroad program in China, and the third was a global service project whose purpose was to design an irrigation system for two small farms in Rwanda. The research questions guiding this study were: 1. What specific knowledge, skills, and attitudes are students gaining from participation in their respective global engineering programs? 2. What kinds of experiences are resulting in these learning outcomes? Interviews were used to elicit the experiences and learning outcomes of participants in this study. Program administrators were also interviewed for their perspectives on the experiences and learning outcomes of participants for the purpose of triangulation. The study identified more than 50 outcomes that resulted from students' experiences in these three programs. The most prevalent outcomes across all three programs included knowledge of culture, openness to new experiences and other cultures, and communication

  5. NASA software documentation standard software engineering program

    Science.gov (United States)

    1991-01-01

    The NASA Software Documentation Standard (hereinafter referred to as Standard) can be applied to the documentation of all NASA software. This Standard is limited to documentation format and content requirements. It does not mandate specific management, engineering, or assurance standards or techniques. This Standard defines the format and content of documentation for software acquisition, development, and sustaining engineering. Format requirements address where information shall be recorded and content requirements address what information shall be recorded. This Standard provides a framework to allow consistency of documentation across NASA and visibility into the completeness of project documentation. This basic framework consists of four major sections (or volumes). The Management Plan contains all planning and business aspects of a software project, including engineering and assurance planning. The Product Specification contains all technical engineering information, including software requirements and design. The Assurance and Test Procedures contains all technical assurance information, including Test, Quality Assurance (QA), and Verification and Validation (V&V). The Management, Engineering, and Assurance Reports is the library and/or listing of all project reports.

  6. Human Factors Engineering and Ergonomics in Systems Engineering

    Science.gov (United States)

    Whitmore, Mihriban

    2017-01-01

    The study, discovery, and application of information about human abilities, human limitations, and other human characteristics to the design of tools, devices, machines, systems, job tasks and environments for effective human performance.

  7. Human-Centered Software Engineering: Software Engineering Architectures, Patterns, and Sodels for Human Computer Interaction

    Science.gov (United States)

    Seffah, Ahmed; Vanderdonckt, Jean; Desmarais, Michel C.

    The Computer-Human Interaction and Software Engineering (CHISE) series of edited volumes originated from a number of workshops and discussions over the latest research and developments in the field of Human Computer Interaction (HCI) and Software Engineering (SE) integration, convergence and cross-pollination. A first volume in this series (CHISE Volume I - Human-Centered Software Engineering: Integrating Usability in the Development Lifecycle) aims at bridging the gap between the field of SE and HCI, and addresses specifically the concerns of integrating usability and user-centered systems design methods and tools into the software development lifecycle and practices. This has been done by defining techniques, tools and practices that can fit into the entire software engineering lifecycle as well as by defining ways of addressing the knowledge and skills needed, and the attitudes and basic values that a user-centered development methodology requires. The first volume has been edited as Vol. 8 in the Springer HCI Series (Seffah, Gulliksen and Desmarais, 2005).

  8. Nuclear Engine System Simulation (NESS). Volume 1: Program user's guide

    Science.gov (United States)

    Pelaccio, Dennis G.; Scheil, Christine M.; Petrosky, Lyman J.

    1993-03-01

    A Nuclear Thermal Propulsion (NTP) engine system design analysis tool is required to support current and future Space Exploration Initiative (SEI) propulsion and vehicle design studies. Currently available NTP engine design models are those developed during the NERVA program in the 1960's and early 1970's and are highly unique to that design or are modifications of current liquid propulsion system design models. To date, NTP engine-based liquid design models lack integrated design of key NTP engine design features in the areas of reactor, shielding, multi-propellant capability, and multi-redundant pump feed fuel systems. Additionally, since the SEI effort is in the initial development stage, a robust, verified NTP analysis design tool could be of great use to the community. This effort developed an NTP engine system design analysis program (tool), known as the Nuclear Engine System Simulation (NESS) program, to support ongoing and future engine system and stage design study efforts. In this effort, Science Applications International Corporation's (SAIC) NTP version of the Expanded Liquid Engine Simulation (ELES) program was modified extensively to include Westinghouse Electric Corporation's near-term solid-core reactor design model. The ELES program has extensive capability to conduct preliminary system design analysis of liquid rocket systems and vehicles. The program is modular in nature and is versatile in terms of modeling state-of-the-art component and system options as discussed. The Westinghouse reactor design model, which was integrated in the NESS program, is based on the near-term solid-core ENABLER NTP reactor design concept. This program is now capable of accurately modeling (characterizing) a complete near-term solid-core NTP engine system in great detail, for a number of design options, in an efficient manner. The following discussion summarizes the overall analysis methodology, key assumptions, and capabilities associated with the NESS presents an

  9. Nuclear Engine System Simulation (NESS). Volume 1: Program user's guide

    Science.gov (United States)

    Pelaccio, Dennis G.; Scheil, Christine M.; Petrosky, Lyman J.

    1993-01-01

    A Nuclear Thermal Propulsion (NTP) engine system design analysis tool is required to support current and future Space Exploration Initiative (SEI) propulsion and vehicle design studies. Currently available NTP engine design models are those developed during the NERVA program in the 1960's and early 1970's and are highly unique to that design or are modifications of current liquid propulsion system design models. To date, NTP engine-based liquid design models lack integrated design of key NTP engine design features in the areas of reactor, shielding, multi-propellant capability, and multi-redundant pump feed fuel systems. Additionally, since the SEI effort is in the initial development stage, a robust, verified NTP analysis design tool could be of great use to the community. This effort developed an NTP engine system design analysis program (tool), known as the Nuclear Engine System Simulation (NESS) program, to support ongoing and future engine system and stage design study efforts. In this effort, Science Applications International Corporation's (SAIC) NTP version of the Expanded Liquid Engine Simulation (ELES) program was modified extensively to include Westinghouse Electric Corporation's near-term solid-core reactor design model. The ELES program has extensive capability to conduct preliminary system design analysis of liquid rocket systems and vehicles. The program is modular in nature and is versatile in terms of modeling state-of-the-art component and system options as discussed. The Westinghouse reactor design model, which was integrated in the NESS program, is based on the near-term solid-core ENABLER NTP reactor design concept. This program is now capable of accurately modeling (characterizing) a complete near-term solid-core NTP engine system in great detail, for a number of design options, in an efficient manner. The following discussion summarizes the overall analysis methodology, key assumptions, and capabilities associated with the NESS presents an

  10. Youth for Astronomy & Engineering Program: Engaging Local Families and Partners

    Science.gov (United States)

    Anderson, Tania

    2017-01-01

    Youth for Astronomy and Engineering (YAE) is a program in the Space Telescope Science Institute's Office of Communication and Public Outreach designed to engage the local community in science, technology, engineering, and mathematics (STEM). This is accomplished through a series of yearly events such as astronomy and engineering clubs for students, family nights, and star parties. These events leverage our mission science to expose participants to the latest science discoveries (Hubble), new developments in space technology (James Webb), STEM career information, and activities that are representative of the work done by individuals in the astronomical and engineering fields. The YAE program helps provide a progression of opportunities for audiences by attracting and identifying highly-engaged individuals for participation in more intensive experiences. It also helps increase our impact by creating a network for piloting educational outreach initiatives at the local level before nationwide release. This poster will highlight the YAE program.

  11. The women in science and engineering scholars program

    Science.gov (United States)

    Falconer, Etta Z.; Guy, Lori Ann

    1989-01-01

    The Women in Science and Engineering Scholars Program provides scientifically talented women students, including those from groups underrepresented in the scientific and technical work force, with the opportunity to pursue undergraduate studies in science and engineering in the highly motivating and supportive environment of Spelman College. It also exposes students to research training at NASA Centers during the summer. The program provides an opportunity for students to increase their knowledge of career opportunities at NASA and to strengthen their motivation through exposure to NASA women scientists and engineers as role models. An extensive counseling and academic support component to maximize academic performance supplements the instructional and research components. The program is designed to increase the number of women scientists and engineers with graduate degrees, particularly those with an interest in a career with NASA.

  12. Effective Software Engineering Leadership for Development Programs

    Science.gov (United States)

    Cagle West, Marsha

    2010-01-01

    Software is a critical component of systems ranging from simple consumer appliances to complex health, nuclear, and flight control systems. The development of quality, reliable, and effective software solutions requires the incorporation of effective software engineering processes and leadership. Processes, approaches, and methodologies for…

  13. Effective Software Engineering Leadership for Development Programs

    Science.gov (United States)

    Cagle West, Marsha

    2010-01-01

    Software is a critical component of systems ranging from simple consumer appliances to complex health, nuclear, and flight control systems. The development of quality, reliable, and effective software solutions requires the incorporation of effective software engineering processes and leadership. Processes, approaches, and methodologies for…

  14. Engineering a General Education Program: Designing Mechanical Engineering General Education Courses

    Science.gov (United States)

    Fagette, Paul; Chen, Shih-Jiun; Baran, George R.; Samuel, Solomon P.; Kiani, Mohammad F.

    2013-01-01

    The Department of Mechanical Engineering at our institution created two engineering courses for the General Education Program that count towards second level general science credit (traditional science courses are first level). The courses were designed for the general student population based upon the requirements of our General Education Program…

  15. Engineering a General Education Program: Designing Mechanical Engineering General Education Courses

    Science.gov (United States)

    Fagette, Paul; Chen, Shih-Jiun; Baran, George R.; Samuel, Solomon P.; Kiani, Mohammad F.

    2013-01-01

    The Department of Mechanical Engineering at our institution created two engineering courses for the General Education Program that count towards second level general science credit (traditional science courses are first level). The courses were designed for the general student population based upon the requirements of our General Education Program…

  16. Final report for the 1996 Engineer Starters Program (Pre-Freshmen Enrichment Program)

    Energy Technology Data Exchange (ETDEWEB)

    Sharpe, L. Jr.

    1996-08-15

    This report has been developed for the North Carolina Agricultural and Technical State University College of Engineering, Department of Energy and other foundations/corporations sponsoring the 1996 Engineer Starters Program and for general information. The College of Engineering conducted its Annual outreach program for Middle and High School students from July 8 to August 2, 1996. The continuing primary goal of this program is to expose youth to the various challenging opportunities in the Mathematics and Science based careers, Engineering and Technology. The curriculum for the summer of 1996 included: Mathematics; Science; Computers; Graphics; Problem Solving; Career Explorations; Communications; Field Trips to Manufacturing Plants/Industries; and Engineering Projects/Designs. The 1996 program included rising seventh through tenth graders. Parental involvement was instituted as a vital component of the summer experiences. The primary objective is to increase the number of minorities entering engineering and science professions.

  17. Development of Education Program for Okinawa Model Creative and Capable Engineers in Advanced Welding Technology

    Science.gov (United States)

    Manabe, Yukio; Matsue, Junji; Makishi, Takashi; Higa, Yoshikazu; Matsuda, Shoich

    Okinawa National College of Technology proposed “Educational Program for Practically Skilled Engineers in Advanced Welding Technology in Okinawa Style” to the Ministry of Economy, Trade and Industry and was adopted as a 2-year project starting from 2005. This project designed to fit for the regional characteristics of Okinawa, aims to develop the core human resources program that will help reinforce and innovate the welding engineering in the manufacturing industries. In 2005, the education program and the original textbook were developed, and in 2006, a proof class was held to confirm the suitability and the effectiveness of the program and the textbook in order to improve the attendees' basics and the application ability of welding. The results were quite positive. Also, by collaborating with the Japan Welding Society, points scored in this course were authorized as the education points of IIW international welding engineer qualification.

  18. RECOMMENDATIONS ON THE UNDERGRADUATE MATHEMATICS PROGRAM FOR ENGINEERS AND PHYSICISTS.

    Science.gov (United States)

    DURST, LINCOLN K.

    THIS REPORT PRESENTS A PROGRAM FOR THE UNDERGRADUATE MATHEMATICAL PREPARATION OF ENGINEERS AND PHYSICISTS. THE FOLLOWING STATEMENTS SERVE AS UNDERLYING ASSUMPTIONS FOR ANYONE EXPECTING TO MAKE USE OF THE RECOMMENDATIONS--(1) THE PROGRAM IS ONE FOR THE PRESENT AND THE PROPOSALS ARE SUCH THAT THEY CAN BE CONTINUALLY MODIFIED TO KEEP UP WITH FUTURE…

  19. CPEP Connecticut Pre-Engineering Program. Formative Report.

    Science.gov (United States)

    Bruckerhoff, Charles; Bruckerhoff, Theresa

    This report evaluates the 1996 Connecticut Pre-Engineering Program (CPEP) Summer Science Camp, a 5-week educational program for upper middle school students that emphasizes processes of thinking and development of personal and social attitudes that are appropriate for academic success, especially in the areas of mathematics and science.…

  20. Ceramic regenerator systems development program. [for automobile gas turbine engines

    Science.gov (United States)

    Cook, J. A.; Fucinari, C. A.; Lingscheit, J. N.; Rahnke, C. J.

    1977-01-01

    Ceramic regenerator cores are considered that can be used in passenger car gas turbine engines, Stirling engines, and industrial/truck gas turbine engines. Improved materials and design concepts aimed at reducing or eliminating chemical attack were placed on durability test in Ford 707 industrial gas turbine engines. The results of 19,600 hours of turbine engine durability testing are described. Two materials, aluminum silicate and magnesium aluminum silicate, continue to show promise toward achieving the durability objectives of this program. A regenerator core made from aluminum silicate showed minimal evidence of chemical attack damage after 6935 hours of engine test at 800 C and another showed little distress after 3510 hours at 982 C. Results obtained in ceramic material screening tests, aerothermodynamic performance tests, stress analysis, cost studies, and material specifications are also included.

  1. Engineering embedded systems physics, programs, circuits

    CERN Document Server

    Hintenaus, Peter

    2015-01-01

    This is a textbook for graduate and final-year-undergraduate computer-science and electrical-engineering students interested in the hardware and software aspects of embedded and cyberphysical systems design. It is comprehensive and self-contained, covering everything from the basics to case-study implementation. Emphasis is placed on the physical nature of the problem domain and of the devices used. The reader is assumed to be familiar on a theoretical level with mathematical tools like ordinary differential equation and Fourier transforms. In this book these tools will be put to practical use. Engineering Embedded Systems begins by addressing basic material on signals and systems, before introducing to electronics. Treatment of digital electronics accentuating synchronous circuits and including high-speed effects proceeds to micro-controllers, digital signal processors and programmable logic. Peripheral units and decentralized networks are given due weight. The properties of analog circuits and devices like ...

  2. Air Force Engineering Research Initiation Grant Program

    Science.gov (United States)

    1994-06-21

    Wisconsin "Investigation of the Role of Structure in the Dynamic Response of Electrorheological Suspensions" RI-B-92-08 Prof. Yozo Mikata Old Dominion...on a direct output feedback control law. In this study, piezoelectric ceramic elements were used as both actuator and sensor. The rod vibration was... ELECTRORHEOLOGICAL SUSPENSIONS FINAL REPORT Air Force Engineering Research Initiation Grant RI-B-92-07 D. J. Klingenberg Department of Chemical

  3. Engineered human dicentric chromosomes show centromere plasticity.

    Science.gov (United States)

    Higgins, Anne W; Gustashaw, Karen M; Willard, Huntington F

    2005-01-01

    The centromere is essential for the faithful distribution of a cell's genetic material to subsequent generations. Despite intense scrutiny, the precise genetic and epigenetic basis for centromere function is still unknown. Here, we have used engineered dicentric human chromosomes to investigate mammalian centromere structure and function. We describe three classes of dicentric chromosomes isolated in different cell lines: functionally monocentric chromosomes, in which one of the two genetically identical centromeres is consistently inactivated; functionally dicentric chromosomes, in which both centromeres are consistently active; and dicentric chromosomes heterogeneous with respect to centromere activity. A study of serial single cell clones from heterogeneous cell lines revealed that while centromere activity is usually clonal, the centromere state (i.e. functionally monocentric or dicentric) in some lines can switch within a growing population of cells. Because pulsed field gel analysis indicated that the DNA at the centromeres of these chromosomes did not change detectably, this switching of the centromere state is most likely due to epigenetic changes. Inactivation of one of the two active centromeres in a functionally dicentric chromosome was observed in a percentage of cells after treatment with Trichostatin A, an inhibitor of histone deacetylation. This study provides evidence that the activity of human centromeres, while largely stable, can be subject to dynamic change, most likely due to epigenetic modification.

  4. Human Genetic Engineering: A Survey of Student Value Stances

    Science.gov (United States)

    Wilson, Sara McCormack; And Others

    1975-01-01

    Assesses the values of high school and college students relative to human genetic engineering and recommends that biology educators explore instructional strategies merging human genetic information with value clarification techniques. (LS)

  5. RNA-guided human genome engineering via Cas9

    National Research Council Canada - National Science Library

    Mali, Prashant; Yang, Luhan; Esvelt, Kevin M; Aach, John; Guell, Marc; DiCarlo, James E; Norville, Julie E; Church, George M

    2013-01-01

    .... We also compute a genome-wide resource of ~190 K unique gRNAs targeting ~40.5% of human exons. Our results establish an RNA-guided editing tool for facile, robust, and multiplexable human genome engineering.

  6. Genetic program based data mining to reverse engineer digital logic

    Science.gov (United States)

    Smith, James F., III; Nguyen, Thanh Vu H.

    2006-04-01

    A data mining based procedure for automated reverse engineering and defect discovery has been developed. The data mining algorithm for reverse engineering uses a genetic program (GP) as a data mining function. A genetic program is an algorithm based on the theory of evolution that automatically evolves populations of computer programs or mathematical expressions, eventually selecting one that is optimal in the sense it maximizes a measure of effectiveness, referred to as a fitness function. The system to be reverse engineered is typically a sensor. Design documents for the sensor are not available and conditions prevent the sensor from being taken apart. The sensor is used to create a database of input signals and output measurements. Rules about the likely design properties of the sensor are collected from experts. The rules are used to create a fitness function for the genetic program. Genetic program based data mining is then conducted. This procedure incorporates not only the experts' rules into the fitness function, but also the information in the database. The information extracted through this process is the internal design specifications of the sensor. Uncertainty related to the input-output database and the expert based rule set can significantly alter the reverse engineering results. Significant experimental and theoretical results related to GP based data mining for reverse engineering will be provided. Methods of quantifying uncertainty and its effects will be presented. Finally methods for reducing the uncertainty will be examined.

  7. Software Engineering Program: Software Process Improvement Guidebook

    Science.gov (United States)

    1996-01-01

    The purpose of this document is to provide experience-based guidance in implementing a software process improvement program in any NASA software development or maintenance community. This guidebook details how to define, operate, and implement a working software process improvement program. It describes the concept of the software process improvement program and its basic organizational components. It then describes the structure, organization, and operation of the software process improvement program, illustrating all these concepts with specific NASA examples. The information presented in the document is derived from the experiences of several NASA software organizations, including the SEL, the SEAL, and the SORCE. Their experiences reflect many of the elements of software process improvement within NASA. This guidebook presents lessons learned in a form usable by anyone considering establishing a software process improvement program within his or her own environment. This guidebook attempts to balance general and detailed information. It provides material general enough to be usable by NASA organizations whose characteristics do not directly match those of the sources of the information and models presented herein. It also keeps the ideas sufficiently close to the sources of the practical experiences that have generated the models and information.

  8. A systems engineering view of the human in space

    Science.gov (United States)

    Anderson, John L.

    1987-01-01

    A model of the human as an 'engineered' system provides a starting point for determining human requirements and performance on an equivalent basis with technological systems. The human as an engineered system with performance requirements is defined to consist of four subsystems: cognitive, psychological, biomechanical, and biomedical. It is suggested that the treatment of the psychological subsystem as one that modulates the efficiency and quality of human performance offers a particular approach for examining and characterizing psychological effects.

  9. Electric Utility Transmission and Distribution Line Engineering Program

    Energy Technology Data Exchange (ETDEWEB)

    Peter McKenny

    2010-08-31

    Economic development in the United States depends on a reliable and affordable power supply. The nation will need well educated engineers to design a modern, safe, secure, and reliable power grid for our future needs. An anticipated shortage of qualified engineers has caused considerable concern in many professional circles, and various steps are being taken nationwide to alleviate the potential shortage and ensure the North American power system's reliability, and our world-wide economic competitiveness. To help provide a well-educated and trained workforce which can sustain and modernize the nation's power grid, Gonzaga University's School of Engineering and Applied Science has established a five-course (15-credit hour) Certificate Program in Transmission and Distribution (T&D) Engineering. The program has been specifically designed to provide working utility engineering professionals with on-line access to advanced engineering courses which cover modern design practice with an industry-focused theoretical foundation. A total of twelve courses have been developed to-date and students may select any five in their area of interest for the T&D Certificate. As each course is developed and taught by a team of experienced engineers (from public and private utilities, consultants, and industry suppliers), students are provided a unique opportunity to interact directly with different industry experts over the eight weeks of each course. Course material incorporates advanced aspects of civil, electrical, and mechanical engineering disciplines that apply to power system design and are appropriate for graduate engineers. As such, target students for the certificate program include: (1) recent graduates with a Bachelor of Science Degree in an engineering field (civil, mechanical, electrical, etc.); (2) senior engineers moving from other fields to the utility industry (i.e. paper industry to utility engineering or project management positions); and (3) regular

  10. Electric Utility Transmission and Distribution Line Engineering Program

    Energy Technology Data Exchange (ETDEWEB)

    Peter McKenny

    2010-08-31

    Economic development in the United States depends on a reliable and affordable power supply. The nation will need well educated engineers to design a modern, safe, secure, and reliable power grid for our future needs. An anticipated shortage of qualified engineers has caused considerable concern in many professional circles, and various steps are being taken nationwide to alleviate the potential shortage and ensure the North American power system's reliability, and our world-wide economic competitiveness. To help provide a well-educated and trained workforce which can sustain and modernize the nation's power grid, Gonzaga University's School of Engineering and Applied Science has established a five-course (15-credit hour) Certificate Program in Transmission and Distribution (T&D) Engineering. The program has been specifically designed to provide working utility engineering professionals with on-line access to advanced engineering courses which cover modern design practice with an industry-focused theoretical foundation. A total of twelve courses have been developed to-date and students may select any five in their area of interest for the T&D Certificate. As each course is developed and taught by a team of experienced engineers (from public and private utilities, consultants, and industry suppliers), students are provided a unique opportunity to interact directly with different industry experts over the eight weeks of each course. Course material incorporates advanced aspects of civil, electrical, and mechanical engineering disciplines that apply to power system design and are appropriate for graduate engineers. As such, target students for the certificate program include: (1) recent graduates with a Bachelor of Science Degree in an engineering field (civil, mechanical, electrical, etc.); (2) senior engineers moving from other fields to the utility industry (i.e. paper industry to utility engineering or project management positions); and (3) regular

  11. Short educational programs in optical design and engineering

    Science.gov (United States)

    Voznesenskaya, Anna; Romanova, Galina; Bakholdin, Alexey; Tolstoba, Nadezhda; Ezhova, Kseniia

    2016-09-01

    Globalization and diversification of education in optical engineering causes a number of new phenomena in students' learning paths. Many students have an interest to get some courses in other universities, to study in international environment, to broaden not only professional skills but social links and see the sights as well etc. Participation in short educational programs (e.g. summer / winter schools, camps etc.) allows students from different universities to learn specific issues in their or in some neighbor field and also earn some ECTS for the transcript of records. ITMO University provides a variety of short educational programs in optical design and engineering oriented for different background level, such are: Introduction into optical engineering, Introduction into applied and computer optics, Optical system design, Image modeling and processing, Design of optical devices and components. Depending on students' educational background these programs are revised and adopted each time. Usually the short educational programs last 4 weeks and provide 4 ECTS. The short programs utilize a set of out-of date educational technologies like problem-based learning, case-study and distance-learning and evaluation. Practically, these technologies provide flexibility of the educational process and intensive growth of the learning outcomes. Students are satisfied with these programs very much. In their feedbacks they point a high level of practical significance, experienced teaching staff, scholarship program, excellent educational environment, as well as interesting social program and organizational support.

  12. Design Considerations for Human Rating of Liquid Rocket Engines

    Science.gov (United States)

    Parkinson, Douglas

    2010-01-01

    I.Human-rating is specific to each engine; a. Context of program/project must be understood. b. Engine cannot be discussed independently from vehicle and mission. II. Utilize a logical combination of design, manufacturing, and test approaches a. Design 1) It is crucial to know the potential ways a system can fail, and how a failure can propagate; 2) Fault avoidance, fault tolerance, DFMR, caution and warning all have roles to play. b. Manufacturing and Assembly; 1) As-built vs. as-designed; 2) Review procedures for assembly and maintenance periodically; and 3) Keep personnel trained and certified. c. There is no substitute for test: 1) Analytical tools are constantly advancing, but still need test data for anchoring assumptions; 2) Demonstrate robustness and explore sensitivities; 3) Ideally, flight will be encompassed by ground test experience. III. Consistency and repeatability is key in production a. Maintain robust processes and procedures for inspection and quality control based upon development and qualification experience; b. Establish methods to "spot check" quality and consistency in parts: 1) Dedicated ground test engines; 2) Random components pulled from the line/lot to go through "enhanced" testing.

  13. Computer Program Re-layers Engineering Drawings

    Science.gov (United States)

    Crosby, Dewey C., III

    1990-01-01

    RULCHK computer program aids in structuring layers of information pertaining to part or assembly designed with software described in article "Software for Drawing Design Details Concurrently" (MFS-28444). Checks and optionally updates structure of layers for part. Enables designer to construct model and annotate its documentation without burden of manually layering part to conform to standards at design time.

  14. Introducing Software Engineering by means of Extreme Programming

    DEFF Research Database (Denmark)

    Hedin, G.; Bendix, Lars Gotfred; Magnusson, B.

    2003-01-01

    This paper reports on experience from teaching basic software engineering concepts by using Extreme Programming in a second year undergraduate course taken by 107 students. We describe how this course fits into a wider programme on software engineering and technology and report our experience from...... running and improving the course. Particularly important aspects of our set-up includes team coaching (by older students) and "team-in-one-room". Our experience so far is very positive and we see that students get a good basic understanding of the important concepts in software engineering, rooted...

  15. Introducing Software Engineering by means of Extreme Programming

    DEFF Research Database (Denmark)

    Hedin, G.; Bendix, Lars Gotfred; Magnusson, B.

    2003-01-01

    This paper reports on experience from teaching basic software engineering concepts by using Extreme Programming in a second year undergraduate course taken by 107 students. We describe how this course fits into a wider programme on software engineering and technology and report our experience from...... running and improving the course. Particularly important aspects of our set-up includes team coaching (by older students) and "team-in-one-room". Our experience so far is very positive and we see that students get a good basic understanding of the important concepts in software engineering, rooted...

  16. Innovating engineering study programs for a sustainable society

    DEFF Research Database (Denmark)

    Schjær-Jacobsen, Hans; Andersen, Birte Møller; Molin, Jesper

    2011-01-01

    of Engineering (IHK) supports this process by innovation of the engineering study programs offered by the institution to deliver on the necessary sustainable competences acquired by our engineering students. The paper describes the sustainability strategy developed to transform IHK into a sustainable institution......The Danish government as well as regional and municipal authority has issued ambitious goals and plans for building a sustainable future by developing and implementing alternative practices and technological solutions to societal needs. As an educational institution Copenhagen University College...... mass and earth energy, monitoring and reducing energy consumption in buildings and transport, and application of cradle-to-cradle concepts in product development and manufacturing including circular logistics....

  17. Programming in C++ for engineering and science

    CERN Document Server

    Nyhoff, Larry

    2012-01-01

    ""The book is lavishly illustrated with examples and exercises, which would make it both an ideal course companion and a book for private study. The author's abilities to explain briefly the history of computing and to write an engaging text are to be commended. If you buy only one text on programming in C++, then this should be the one for you.""-Carl M. O'Brien, International Statistical Review (2013), 81

  18. Four-Cylinder Stirling-Engine Computer Program

    Science.gov (United States)

    Daniele, C. J.; Lorenzo, C. F.

    1986-01-01

    Computer program developed for simulating steady-state and transient performance of four-cylinder Stirling engine. In model, four cylinders interconnected by four working spaces. Each working space contains seven volumes: one for expansion space, heater, cooler, and compression space and three for regenerator. Thermal time constant for regenerator mass associated with each regenator gas volume. Former code generates results very quickly, since it has only 14 state variables with no energy equation. Current code then used to study various aspects of Stirling engine in much more detail. Program written in FORTRAN IV for use on IBM 370 computer.

  19. Recent progress in engineering human-associated microbiomes.

    Science.gov (United States)

    Yaung, Stephanie J; Church, George M; Wang, Harris H

    2014-01-01

    Recent progress in molecular biology and genetics opens up the possibility of engineering a variety of biological systems, from single-cellular to multicellular organisms. The consortia of microbes that reside on the human body, the human-associated microbiota, are particularly interesting as targets for forward engineering and manipulation due to their relevance in health and disease. New technologies in analysis and perturbation of the human microbiota will lead to better diagnostic and therapeutic strategies against diseases of microbial origin or pathogenesis. Here, we discuss recent advances that are bringing us closer to realizing the true potential of an engineered human-associated microbial community.

  20. Nuclear Explosion Monitoring Research and Engineering Program - Strategic Plan

    Energy Technology Data Exchange (ETDEWEB)

    Casey, Leslie A. [DOE/NNSA

    2004-09-01

    The Department of Energy (DOE)/National Nuclear Security Administration (NNSA) Nuclear Explosion Monitoring Research and Engineering (NEM R&E) Program is dedicated to providing knowledge, technical expertise, and products to US agencies responsible for monitoring nuclear explosions in all environments and is successful in turning scientific breakthroughs into tools for use by operational monitoring agencies. To effectively address the rapidly evolving state of affairs, the NNSA NEM R&E program is structured around three program elements described within this strategic plan: Integration of New Monitoring Assets, Advanced Event Characterization, and Next-Generation Monitoring Systems. How the Program fits into the National effort and historical accomplishments are also addressed.

  1. A research agenda for academic petroleum engineering programs

    Energy Technology Data Exchange (ETDEWEB)

    Calhoun, J.C. Jr.

    1990-03-31

    The development of a research agenda should be a direct way of portraying the scope of petroleum engineering, of identifying the critical technological issues faced by the profession,of elucidating the gaps between the existing research resources and the needs. and of outlining a program of research through which the petroleum engineering departments can be collectively of maximum service. Such an agenda would be of value to the profession of petroleum engineering, to industry and to government agencies, as well as to the faculty and students of the petroleum engineering departments. The purposes of the activity that led to this report, therefore, were to develop a statement to serve as a beginning research agenda for the petroleum engineering academic community; to bring together representatives of the petroleum engineering academic community to recognize the importance of developing a consensus posture with respect to research; and to provide a document that will assist in portraying to industry, government agencies and others the problems and needs of the petroleum engineering departments for conducting research. Contents of this report include; introduction; the background; the scope of petroleum engineering research; priority research topics and technological issues; non-technological research issues; and conclusions and recommendations.

  2. A research agenda for academic petroleum engineering programs. [Final report

    Energy Technology Data Exchange (ETDEWEB)

    Calhoun, J.C. Jr.

    1990-03-31

    The development of a research agenda should be a direct way of portraying the scope of petroleum engineering, of identifying the critical technological issues faced by the profession,of elucidating the gaps between the existing research resources and the needs. and of outlining a program of research through which the petroleum engineering departments can be collectively of maximum service. Such an agenda would be of value to the profession of petroleum engineering, to industry and to government agencies, as well as to the faculty and students of the petroleum engineering departments. The purposes of the activity that led to this report, therefore, were to develop a statement to serve as a beginning research agenda for the petroleum engineering academic community; to bring together representatives of the petroleum engineering academic community to recognize the importance of developing a consensus posture with respect to research; and to provide a document that will assist in portraying to industry, government agencies and others the problems and needs of the petroleum engineering departments for conducting research. Contents of this report include; introduction; the background; the scope of petroleum engineering research; priority research topics and technological issues; non-technological research issues; and conclusions and recommendations.

  3. Experiences in the application of human factors engineering to human-system interface modernization

    Energy Technology Data Exchange (ETDEWEB)

    Trueba Alonso, Pedro; Fernandez Illobre, Luis; Ortega Pascual, Fernando [Tecnatom S.A., San Sebastian de los Reyes (Spain). Simulation and Control Rooms Div.

    2015-07-15

    Almost all the existing Nuclear Power Plants (NPPs) include plans to modernize their existing Instrumentation and Control (I and C) systems and associated Human System Interfaces (HSIs), due to obsolescence problems. Tecnatom, S.A. has been participating in modernization programs in NPPs to help them to plan, specify, design and implement the modernization of control rooms and associated I and C and HSIs. The application of Human Factors Engineering (HFE) in modernization programs is nowadays unavoidable. This is because is becoming a regulatory requirement, and also because it is needed to ensure that any plant modification, involving the modernization of I and C and HSI, is well designed to improve overall plant operations, reliability, and safety. This paper shows some experiences obtained during the application of HFE to the modernization of these HSIs. The experience applying HFE in modernizations and design modifications show a positive effect, improving the associated HSIs, with the acceptability of the final user.

  4. Allison engine ATS program technical review

    Energy Technology Data Exchange (ETDEWEB)

    Mukavetz, D. [Allison Engine Co., Indianpolis, IN (United States)

    1995-10-01

    Gas turbines in industrial and utility applications can help meet future national and worldwide power generation requirements. Turbine systems burning natural gas offer environmentally sound and economical power generation and cogeneration. Since U.S. demand alone will require up to 15 gigawatts per year of new and replacement capacity after the year 2000, the availability of Advanced Turbine Systems (ATS) to fill a share of this need will save significant amounts of fuel and benefit the environment. Implementation of the ATS Program will also keep U.S. manufacturers on the cutting ledge of turbine technology for power generation applications and enhance the nation`s economic competitiveness.

  5. The Programming Language as Human Interface

    NARCIS (Netherlands)

    Pemberton, S.

    2014-01-01

    Programming languages are mostly not designed for humans, but for computers. As a result, programming time is increased by the necessity for programmers to translate problem description into a step-wise method of solving the problem. This demonstration shows a step towards producing more human-orien

  6. The collaborative program of research in engineering science

    Energy Technology Data Exchange (ETDEWEB)

    1990-12-01

    MIT and Idaho National Engineering Laboratory are continuing the program of collaborative research on energy-related engineering. The program involves research in the following areas: (1) mathematical modeling of thermal plasma systems, (2) high-temperature gas-particle reactions, (3) metal transfer in gas-metal arc welding, (4) multivariate control of gas-metal arc welding, (5) fundamentals of elastic-plastic fracture, (6) comminution of energy materials, and (7) synthesis and optimization of integrated chemical processes. A key objective of this collaborative program is to serve as a prototype for other university/laboratory collaborative programs. Another important goal is to enhance the transfer of new technology to the industrial sector.

  7. Human Engineering Modeling and Performance Lab Study Project

    Science.gov (United States)

    Oliva-Buisson, Yvette J.

    2014-01-01

    The HEMAP (Human Engineering Modeling and Performance) Lab is a joint effort between the Industrial and Human Engineering group and the KAVE (Kennedy Advanced Visualiations Environment) group. The lab consists of sixteen camera system that is used to capture human motions and operational tasks, through te use of a Velcro suit equipped with sensors, and then simulate these tasks in an ergonomic software package know as Jac, The Jack software is able to identify the potential risk hazards.

  8. Seeking perfection: a Kantian look at human genetic engineering.

    Science.gov (United States)

    Gunderson, Martin

    2007-01-01

    It is tempting to argue that Kantian moral philosophy justifies prohibiting both human germ-line genetic engineering and non-therapeutic genetic engineering because they fail to respect human dignity. There are, however, good reasons for resisting this temptation. In fact, Kant's moral philosophy provides reasons that support genetic engineering-even germ-line and non-therapeutic. This is true of Kant's imperfect duties to seek one's own perfection and the happiness of others. It is also true of the categorical imperative. Kant's moral philosophy does, however, provide limits to justifiable genetic engineering.

  9. Unmasking the social engineer the human element of security

    CERN Document Server

    Hadnagy, Christopher

    2014-01-01

    Learn to identify the social engineer by non-verbal behavior Unmasking the Social Engineer: The Human Element of Security focuses on combining the science of understanding non-verbal communications with the knowledge of how social engineers, scam artists and con men use these skills to build feelings of trust and rapport in their targets. The author helps readers understand how to identify and detect social engineers and scammers by analyzing their non-verbal behavior. Unmasking the Social Engineer shows how attacks work, explains nonverbal communications, and demonstrates with visuals the c

  10. 34 CFR 637.1 - What is the Minority Science and Engineering Improvement Program (MSEIP)?

    Science.gov (United States)

    2010-07-01

    ... ENGINEERING IMPROVEMENT PROGRAM General § 637.1 What is the Minority Science and Engineering Improvement Program (MSEIP)? The Minority Science and Engineering Improvement Program (MSEIP) is designed to effect... 34 Education 3 2010-07-01 2010-07-01 false What is the Minority Science and Engineering...

  11. Innovating engineering study programs for a sustainable society

    DEFF Research Database (Denmark)

    Schjær-Jacobsen, Hans; Andersen, Birte Møller; Molin, Jesper

    2011-01-01

    The Danish government as well as regional and municipal authority has issued ambitious goals and plans for building a sustainable future by developing and implementing alternative practices and technological solutions to societal needs. As an educational institution Copenhagen University College...... of Engineering (IHK) supports this process by innovation of the engineering study programs offered by the institution to deliver on the necessary sustainable competences acquired by our engineering students. The paper describes the sustainability strategy developed to transform IHK into a sustainable institution...... in order to comply with society’s ambitions. Further, the new learning elements introduced in the curriculum of study programs are described and examples of theoretical and practical implementations of specific technical solutions developed by the students are presented. Focus is on such areas as wind, bio...

  12. A survey of program slicing for software engineering

    Science.gov (United States)

    Beck, Jon

    1993-01-01

    This research concerns program slicing which is used as a tool for program maintainence of software systems. Program slicing decreases the level of effort required to understand and maintain complex software systems. It was first designed as a debugging aid, but it has since been generalized into various tools and extended to include program comprehension, module cohesion estimation, requirements verification, dead code elimination, and maintainence of several software systems, including reverse engineering, parallelization, portability, and reuse component generation. This paper seeks to address and define terminology, theoretical concepts, program representation, different program graphs, developments in static slicing, dynamic slicing, and semantics and mathematical models. Applications for conventional slicing are presented, along with a prognosis of future work in this field.

  13. Human factor engineering applied to nuclear power plant design

    Energy Technology Data Exchange (ETDEWEB)

    Manrique, A. [TECNATOM SA, BWR General Electric Business Manager, Madrid (Spain); Valdivia, J.C. [TECNATOM SA, Operation Engineering Project Manager, Madrid (Spain); Jimenez, A. [TECNATOM SA, Operation Engineering Div. Manager, Madrid (Spain)

    2001-07-01

    For the design and construction of new nuclear power plants as well as for maintenance and operation of the existing ones new man-machine interface designs and modifications are been produced. For these new designs Human Factor Engineering must be applied the same as for any other traditional engineering discipline. Advantages of implementing adequate Human Factor Engineering techniques in the design of nuclear reactors have become not only a fact recognized by the majority of engineers and operators but also an explicit requirement regulated and mandatory for the new designs of the so called advanced reactors. Additionally, the big saving achieved by a nuclear power plant having an operating methodology which significantly decreases the risk of operating errors makes it necessary and almost vital its implementation. The first step for this is preparing a plan to incorporate all the Human Factor Engineering principles and developing an integral design of the Instrumentation and Control and Man-machine interface systems. (author)

  14. Design of a Human Reliability Assessment model for structural engineering

    NARCIS (Netherlands)

    De Haan, J.; Terwel, K.C.; Al-Jibouri, S.H.S.

    2013-01-01

    It is generally accepted that humans are the “weakest link” in structural design and construction processes. Despite this, few models are available to quantify human error within engineering processes. This paper demonstrates the use of a quantitative Human Reliability Assessment model within struct

  15. Accreditation of Spanish Engineering Programs, first experiences. The case of the Terrassa School of Engineering

    OpenAIRE

    2016-01-01

    The implementation of the European Space for Higher Education has entailed new requirements for Spanish Higher Education Programs. Regulations (RD 1393, 2007) stablish that university programs, in order to have official validity, must be submitted to an external evaluation process before their official implementation, denominated Validation, and to an ex-post process or Accreditation. Terrassa School of Engineering (EET) was one of the first schools in Spain to adapt to the European Space for...

  16. Inspiring engineering minds to advance human health: the Henry Samueli School of Engineering's Department of BME.

    Science.gov (United States)

    Lee, Abraham; Wirtanen, Erik

    2012-07-01

    The growth of biomedical engineering at The Henry Samueli School of Engineering at the University of California, Irvine (UCI) has been rapid since the Center for Biomedical Engineering was first formed in 1998 [and was later renamed as the Department of Biomedical Engineering (BME) in 2002]. Our current mission statement, “Inspiring Engineering Minds to Advance Human Health,” serves as a reminder of why we exist, what we do, and the core principles that we value and by which we abide. BME exists to advance the state of human health via engineering innovation and practices. To attain our goal, we are empowering our faculty to inspire and mobilize our students to address health problems. We treasure the human being, particularly the human mind and health. We believe that BME is where minds are nurtured, challenged, and disciplined, and it is also where the health of the human is held as a core mission value that deserves our utmost priority (Figure 1). Advancing human health is not a theoretical practice; it requires bridging between disciplines (engineering and medicine) and between communities (academic and industry).

  17. Advanced Materials Development Program: Ceramic Technology for Advanced Heat Engines program plan, 1983--1993

    Energy Technology Data Exchange (ETDEWEB)

    1990-07-01

    The purpose of the Ceramic Technology for Advanced Heat Engines (CTAHE) Project is the development of an industrial technology base capable of providing reliable and cost-effective high temperature ceramic components for application in advanced heat engines. There is a deliberate emphasis on industrial'' in the purpose statement. The project is intended to support the US ceramic and engine industries by providing the needed ceramic materials technology. The heat engine programs have goals of component development and proof-of-concept. The CTAHE Project is aimed at developing generic basic ceramic technology and does not involve specific engine designs and components. The materials research and development efforts in the CTAHE Project are focused on the needs and general requirements of the advanced gas turbine and low heat rejection diesel engines. The CTAHE Project supports the DOE Office of Transportation Systems' heat engine programs, Advanced Turbine Technology Applications (ATTAP) and Heavy Duty Transport (HDT) by providing the basic technology required for development of reliable and cost-effective ceramic components. The heat engine programs provide the iterative component design, fabrication, and test development logic. 103 refs., 18 figs., 11 tabs.

  18. Army/NASA small turboshaft engine digital controls research program

    Science.gov (United States)

    Sellers, J. F.; Baez, A. N.

    1981-01-01

    The emphasis of a program to conduct digital controls research for small turboshaft engines is on engine test evaluation of advanced control logic using a flexible microprocessor based digital control system designed specifically for research on advanced control logic. Control software is stored in programmable memory. New control algorithms may be stored in a floppy disk and loaded directly into memory. This feature facilitates comparative evaluation of different advanced control modes. The central processor in the digital control is an Intel 8086 16 bit microprocessor. Control software is programmed in assembly language. Software checkout is accomplished prior to engine test by connecting the digital control to a real time hybrid computer simulation of the engine. The engine currently installed in the facility has a hydromechanical control modified to allow electrohydraulic fuel metering and VG actuation by the digital control. Simulation results are presented which show that the modern control reduces the transient rotor speed droop caused by unanticipated load changes such as cyclic pitch or wind gust transients.

  19. Requirements engineering for human activity systems

    CSIR Research Space (South Africa)

    Erasmus, J

    2014-10-01

    Full Text Available . Office of the Chief Engineer, NASA, 2007. —. Systems Engineering Handbook. Washington, D.C.: National Aeronautics and Space Administration, 2007. Office of the Deputy Under Secretary of Defense for Acquisition and Technology, Systems and Software... and special tools necessary to perform the verification (NASA 2007). This information will also allow for proper planning and scheduling of the verification activities to be performed throughout the development and realisation of the product. Measures...

  20. Spacecraft Testing Programs: Adding Value to the Systems Engineering Process

    Science.gov (United States)

    Britton, Keith J.; Schaible, Dawn M.

    2011-01-01

    Testing has long been recognized as a critical component of spacecraft development activities - yet many major systems failures may have been prevented with more rigorous testing programs. The question is why is more testing not being conducted? Given unlimited resources, more testing would likely be included in a spacecraft development program. Striking the right balance between too much testing and not enough has been a long-term challenge for many industries. The objective of this paper is to discuss some of the barriers, enablers, and best practices for developing and sustaining a strong test program and testing team. This paper will also explore the testing decision factors used by managers; the varying attitudes toward testing; methods to develop strong test engineers; and the influence of behavior, culture and processes on testing programs. KEY WORDS: Risk, Integration and Test, Validation, Verification, Test Program Development

  1. Engineering Certification Program Self-Study Course, Basic Mathematics. Engineering Management [Series].

    Science.gov (United States)

    Owsley, Fran, Ed.

    This course is part of an engineering certification program for men inspecting construction projects. It presumes some high school training in mathematics and science. The course begins with examples showing the importance of mathematics on the job. Following that is a section on algebra, one on geometry, and one on trigonometry. (KM)

  2. La Vida Robot - High School Engineering Program Combats Engineering Brain Drain

    Energy Technology Data Exchange (ETDEWEB)

    Cameron, Allan; Lajvardi, Fredi (Carl Hayden High School, Phoenix, AZ)

    2006-03-15

    Carl Hayden High School has built an impressive reputation with its robotics club. At a time when interest in science, math and engineering is declining, the Falcon Robotics club has young people fired up about engineering. Their program in underwater robots (MATE) and FIRST robotics is becoming a national model, not for building robots, but for building engineers. Teachers Fredi Lajvardi and Allan Cameron will present their story (How kids 'from the mean streets of Phoenix took on the best from M.I.T. in the national underwater bot championship' - Wired Magazine, April 2005) and how every student needs the opportunity to 'do real engineering.'

  3. Human Research Program: 2010 Annual Report

    Science.gov (United States)

    2010-01-01

    2010 was a year of solid performance for the Human Research Program in spite of major changes in NASA's strategic direction for Human Spaceflight. Last year, the Program completed the final steps in solidifying the management foundation, and in 2010 we achieved exceptional performance from all elements of the research and technology portfolio. We transitioned from creating building blocks to full execution of the management tools for an applied research and technology program. As a team, we continue to deliver the answers and technologies that enable human exploration of space. While the Agency awaits strategic direction for human spaceflight, the Program is well positioned and critically important to helping the Agency achieve its goals.

  4. MatLab Programming for Engineers Having No Formal Programming Knowledge

    Science.gov (United States)

    Shaykhian, Linda H.; Shaykhian, Gholam Ali

    2007-01-01

    MatLab is one of the most widely used very high level programming languages for Scientific and engineering computations. It is very user-friendly and needs practically no formal programming knowledge. Presented here are MatLab programming aspects and not just the MatLab commands for scientists and engineers who do not have formal programming training and also have no significant time to spare for learning programming to solve their real world problems. Specifically provided are programs for visualization. Also, stated are the current limitations of the MatLab, which possibly can be taken care of by Mathworks Inc. in a future version to make MatLab more versatile.

  5. 48th Canadian Chemical Engineering conference: technical program

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-10-01

    This is the official CD-ROM for the Canadian Society for Chemical Engineering annual conference. The documents on the disk can be navigated in the same way as a Web site on the Internet. Web pages are located on the disk. A Web browser is required to view most of the files. The conference program contains abstracts of the more than 300 papers presented at 78 sessions covering all aspects of chemical engineering: fluidized bed, reaction catalysis, environment, new developments, biotechnology, process control, polymers, fluid mechanics, pulp and paper, thermodynamics, multiphase reactors, reaction catalysis, rheology, chemical engineering fundamentals, chemical technology, oil and gas, education, and industrial issues. Five of the abstracts have been abstracted separately.

  6. Cooperative and human aspects of software engineering: CHASE 2010

    DEFF Research Database (Denmark)

    Dittrich, Yvonne; Sharp, Helen C.; Winschiers Theophilus, Heike

    2010-01-01

    Software is created by people -- software engineers in cooperation with domain experts, users and other stakeholders--in varied environments, under various conditions. Thus understanding cooperative and human aspects of software development is crucial to comprehend how and which methods and tools...... are required, to improve the creation and maintenance of software. The 3rd workshop on Cooperative and Human Aspects of Software Engineering held at the International Conference on Software Engineering continued the tradition from earlier workshops and provided a lively forum to discuss current developments...... and high quality research in the field. Further dissemination of research results will lead to an improvement of software development and deployment across the globe....

  7. Stirling Space Engine Program. Volume 1; Final Report

    Science.gov (United States)

    Dhar, Manmohan

    1999-01-01

    The objective of this program was to develop the technology necessary for operating Stirling power converters in a space environment and to demonstrate this technology in full-scale engine tests. Hardware development focused on the Component Test Power Converter (CTPC), a single cylinder, 12.5-kWe engine. Design parameters for the CTPC were 150 bar operating pressure, 70 Hz frequency, and hot-and cold-end temperatures of 1050 K and 525 K, respectively. The CTPC was also designed for integration with an annular sodium heat pipe at the hot end, which incorporated a unique "Starfish" heater head that eliminated highly stressed brazed or weld joints exposed to liquid metal and used a shaped-tubed electrochemical milling process to achieve precise positional tolerances. Selection of materials that could withstand high operating temperatures with long life were another focus. Significant progress was made in the heater head (Udimet 700 and Inconel 718 and a sodium-filled heat pipe); the alternator (polyimide-coated wire with polyimide adhesive between turns and a polyimide-impregnated fiberglass overwrap and samarium cobalt magnets); and the hydrostatic gas bearings (carbon graphite and aluminum oxide for wear couple surfaces). Tests on the CTPC were performed in three phases: cold end testing (525 K), engine testing with slot radiant heaters, and integrated heat pipe engine system testing. Each test phase was successful, with the integrated engine system demonstrating a power level of 12.5 kWe and an overall efficiency of 22 percent in its maiden test. A 1500-hour endurance test was then successfully completed. These results indicate the significant achievements made by this program that demonstrate the viability of Stirling engine technology for space applications.

  8. Survey Result of the Engineering Undergraduate Student's “Human Performance”

    Science.gov (United States)

    Nakayama, Minoru; Takahashi, Hideaki; Kusakabe, Osamu; Ohtaguchi, Kazuhisa; Mizutani, Nobuyasu

    Development of engineer's “Human Performance” is being required to respond to various changes. “Human Performace” is defined as an ability of putting own knowledge and skill to a practical issue. Current engineering undergraduate education promotes to learn this ability. To examine effectiveness of the educational program, a questionnaire consisting of 66 items was developed and the survey was conducted across eight universities. As results, most students recognize importance of the ability, but their achievement is lower for English communication skill and adaptation of cultural difference. They learned the ability on laboratory experience for their thesis, experiment class, club activities, part-time jobs and other activities.

  9. An Assessment of Extreme Programming Based Requirement Engineering Process

    Directory of Open Access Journals (Sweden)

    Muhammad Khalid

    2013-02-01

    Full Text Available Comprehensive requirement engineering (RE process acts as a backbone of any successful project. RE processes are very complex because most of the requirement engineering documentation is written in natural languages, which are less formal and often distract the designers and developers of the system. To streamline different phases of the software lifecycle, first we need to model the requirement document so that we can analyze and integrate the software artifacts. Designers can ensure completeness and consistency of the system by generating models using the requirement documents. In this paper, we have made an attempt to analyze extreme programming based RE approach to understand its utility in the requirement elicitation phase. In this study, different RE process models are evaluated and a comparison of the extreme programming technique is drawn to highlight the merits of the latter technique over the conventional RE techniques.

  10. Introducing PBL to Foreign Studentsin International Engineering Programs

    DEFF Research Database (Denmark)

    Du, Xiangyun; Dahms, Mona-Lisa; Jensen, Lars Peter

    2007-01-01

    programs to develop process competencies from an intercultural perspective. The POL course has had positive effects in terms of helping foreign students understand PBL and develop learning strategies in a PBL setting. However, our experiences show that issues arising from cultural diversity in educational...... settings are more complex than only integrating foreign students into existing programs. More efforts and better strategies are needed to improve intercultural competencies for teaching staff and students, foreigners as well as locals, in engineering education....... to develop process competencies (i.e. skills in project management, collaboration, communication, etc.) in addition to technical skills. This paper presents the development of a course, the Project Organized Learning (POL) course, which has been designed to assist students in international engineering...

  11. Repository-based software engineering program: Concept document

    Science.gov (United States)

    1992-01-01

    This document provides the context for Repository-Based Software Engineering's (RBSE's) evolving functional and operational product requirements, and it is the parent document for development of detailed technical and management plans. When furnished, requirements documents will serve as the governing RBSE product specification. The RBSE Program Management Plan will define resources, schedules, and technical and organizational approaches to fulfilling the goals and objectives of this concept. The purpose of this document is to provide a concise overview of RBSE, describe the rationale for the RBSE Program, and define a clear, common vision for RBSE team members and customers. The document also provides the foundation for developing RBSE user and system requirements and a corresponding Program Management Plan. The concept is used to express the program mission to RBSE users and managers and to provide an exhibit for community review.

  12. An Engineering Research Program for High School Science Teachers: Year Two Changes and Results

    Science.gov (United States)

    DeJong, Brian P.; Yelamarthi, Kumar; Kaya, Tolga

    2016-01-01

    The research experiences for teachers program at Central Michigan University was initiated to team in-service and pre-service teachers with undergraduate engineering students and engineering faculty, in an engineering research setting. During the six-week program, teachers learn engineering concepts and develop high-school instructional material…

  13. New adventures in biomedical engineering: Radiation safety program management

    Energy Technology Data Exchange (ETDEWEB)

    Dickey, D.M. (Washington Hospital Center, DC (United States))

    1991-09-01

    As biomedical/clinical engineers expand their managerial expertise into nontraditional areas, it makes sense that they pursue areas where their formal training in physics and mathematics can be applied. Radiation safety requires having the educational background to understand atomic structure, the nature of radioactivity, mathematics, biology, chemistry, and instrumentation. Program management requires having the administrative experience to manage people, data, files, documentation, and budgets. Radiation safety program management also requires an understanding of how best to prepare for a surprise inspection, similar to but technically more specific than other inspections and surveys previously experienced by the BME/CE professional.

  14. A general-purpose optimization program for engineering design

    Science.gov (United States)

    Vanderplaats, G. N.; Sugimoto, H.

    1986-01-01

    A new general-purpose optimization program for engineering design is described. ADS (Automated Design Synthesis) is a FORTRAN program for nonlinear constrained (or unconstrained) function minimization. The optimization process is segmented into three levels: Strategy, Optimizer, and One-dimensional search. At each level, several options are available so that a total of nearly 100 possible combinations can be created. An example of available combinations is the Augmented Lagrange Multiplier method, using the BFGS variable metric unconstrained minimization together with polynomial interpolation for the one-dimensional search.

  15. Mentoring program for students newly enrolled in an Engineering Degree

    Directory of Open Access Journals (Sweden)

    Juan Pedro Peña-Martín

    2016-10-01

    Full Text Available This work presents a mentoring program for first year engineering students in the Telecommunications Engineering College (ETSIT at the University of Malaga (UMA. Actors involved in the program are professors from staff, veterans mentoring students and, of course, freshmen. All of them has been organized trough the Moodle based Virtual Learning Environment Platform of the UMA. The program has gone through several phases over three years. This paper shows the main objectives of this mentoring program, the initial design to get them where professors played mentor role, and successive changes made to try to improve the results, including the assumption of the mentor role by senior students (peer mentoring. The tools used for program evaluation are shown too. Despite the low participation, it has been a framework for the development of various educational and socializing activities (for mentors and mentees focused on developing generic competences. Furthermore, it has been a research tool to get a better understanding of problems affecting students newly enrolled.

  16. "Human Nature": Chemical Engineering Students' Ideas about Human Relationships with the Natural World

    Science.gov (United States)

    Goldman, Daphne; Assaraf, Orit Ben-Zvi; Shemesh, Julia

    2014-01-01

    While importance of environmental ethics, as a component of sustainable development, in preparing engineers is widely acknowledged, little research has addressed chemical engineers' environmental concerns. This study aimed to address this void by exploring chemical engineering students' values regarding human-nature relationships. The…

  17. "Human Nature": Chemical Engineering Students' Ideas about Human Relationships with the Natural World

    Science.gov (United States)

    Goldman, Daphne; Assaraf, Orit Ben-Zvi; Shemesh, Julia

    2014-01-01

    While importance of environmental ethics, as a component of sustainable development, in preparing engineers is widely acknowledged, little research has addressed chemical engineers' environmental concerns. This study aimed to address this void by exploring chemical engineering students' values regarding human-nature relationships. The study was…

  18. The 2015-2016 SEPMAP Program at NASA JSC: Science, Engineering, and Program Management Training

    Science.gov (United States)

    Graham, L.; Archer, D.; Bakalyar, J.; Berger, E.; Blome, E.; Brown, R.; Cox, S.; Curiel, P.; Eid, R.; Eppler, D.; Fries, M.; Gruener, J.; Haddock, M.; Harder, K.; Hong, T.; McCann, C.; Neiss, K.; Newswander, J.; Odina, J.; Peslier, A.; Quadri, Z.; Ross, S.; Rutovic, M.; Schulte, R.; Thomas, R.; Vos, J.; Waid, M.; William, B.

    2017-01-01

    The Systems Engineering Project Management Advancement Program (SEPMAP) at NASA Johnson Space Center (JSC) is an employee development program designed to provide graduate level training in project management and systems engineering. The program includes an applied learning project with engineering and integrated science goals requirements. The teams were presented with a task: Collect a representative sample set from a field site using a hexacopter platform, as if performing a scientific reconnaissance to assess whether the site is of sufficient scientific interest to justify exploration by astronauts. Four teams worked through the eighteen-month course to design customized sampling payloads integrated with the hexacopter, and then operate the aircraft to meet sampling requirements of number (= 5) and mass (= 5g each). The "Mars Yard" at JSC was utilized for this purpose. This project activity closely parallels NASA plans for the future exploration of Mars, where remote sites will be reconnoitered ahead of crewed exploration.

  19. Genetic engineering of human pluripotent cells using TALE nucleases.

    Science.gov (United States)

    Hockemeyer, Dirk; Wang, Haoyi; Kiani, Samira; Lai, Christine S; Gao, Qing; Cassady, John P; Cost, Gregory J; Zhang, Lei; Santiago, Yolanda; Miller, Jeffrey C; Zeitler, Bryan; Cherone, Jennifer M; Meng, Xiangdong; Hinkley, Sarah J; Rebar, Edward J; Gregory, Philip D; Urnov, Fyodor D; Jaenisch, Rudolf

    2011-07-07

    Targeted genetic engineering of human pluripotent cells is a prerequisite for exploiting their full potential. Such genetic manipulations can be achieved using site-specific nucleases. Here we engineered transcription activator-like effector nucleases (TALENs) for five distinct genomic loci. At all loci tested we obtained human embryonic stem cell (ESC) and induced pluripotent stem cell (iPSC) clones carrying transgenic cassettes solely at the TALEN-specified location. Our data suggest that TALENs employing the specific architectures described here mediate site-specific genome modification in human pluripotent cells with similar efficiency and precision as do zinc-finger nucleases (ZFNs).

  20. Buried waste integrated demonstration human engineered control station. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1994-09-01

    This document describes the Human Engineered Control Station (HECS) project activities including the conceptual designs. The purpose of the HECS is to enhance the effectiveness and efficiency of remote retrieval by providing an integrated remote control station. The HECS integrates human capabilities, limitations, and expectations into the design to reduce the potential for human error, provides an easy system to learn and operate, provides an increased productivity, and reduces the ultimate investment in training. The overall HECS consists of the technology interface stations, supporting engineering aids, platform (trailer), communications network (broadband system), and collision avoidance system.

  1. The McBride Honors Program in Public Affairs for Scientists and Engineers

    Science.gov (United States)

    Harrison, W. J.; Miller, R. L.; Olds, B. M.; Sacks, A. B.

    2006-12-01

    The McBride Honors Program in Public Affairs at The Colorado School of Mines (CSM), instituted in 1978, is an award-winning exemplar in the liberal arts which provides a select number of CSM engineering students an opportunity to cross the boundaries of their technical expertise in engineering and applied science, and to gain the understanding and appreciation of the contexts in which engineering and applied science and all human systems reside, and specifically to explore and integrate the social, cultural, ethical and environmental implications of their future professional judgments and their roles as citizens in varied and complex settings. The 27 semester-hour program of seminars, courses, and off-campus activities features small seminars; a cross-disciplinary approach; and opportunities for one-on-one faculty tutorials, instruction and practice in oral and written communication, a Washington, D.C. public policy seminar, a practicum experience (internship or foreign study). Circumstances external to the McBride Program itself, which include the development and growth of the field of Public Affairs nationally and the persistence of legacy courses, have created the need to revitalize and refocus the historically cross-departmental Program. A recent curriculum reform effort has achieved a more thoroughly interdisciplinary learning experience to educate engineers and scientists who, as called for in the National Academy of Engineering's The Engineer of 2020 "will assume leadership positions from which they can serve as positive influences in the making of public policy and in the administration of government and industry". In this presentation we showcase best practices in curriculum reform, exemplified by a seminar in National policy analysis where students and faculty have recently investigated federal science funding decisions in support of natural hazards including earthquakes, tsunamis, wildland fires, and pandemic disease.

  2. Creation of security engineering programs by the Southwest Surety Institute

    Science.gov (United States)

    Romero, Van D.; Rogers, Bradley; Winfree, Tim; Walsh, Dan; Garcia, Mary Lynn

    1998-12-01

    The Southwest Surety Institute includes Arizona State University (ASU), Louisiana State University (LSU), New Mexico Institute of Mining and Technology (NM Tech), New Mexico State University (NMSU), and Sandia National Laboratories (SNL). The universities currently offer a full spectrum of post-secondary programs in security system design and evaluation, including an undergraduate minor, a graduate program, and continuing education programs. The programs are based on the methodology developed at Sandia National Laboratories over the past 25 years to protect critical nuclear assets. The programs combine basic concepts and principles from business, criminal justice, and technology to create an integrated performance-based approach to security system design and analysis. Existing university capabilities in criminal justice (NMSU), explosives testing and technology (NM Tech and LSU), and engineering technology (ASU) are leveraged to provide unique science-based programs that will emphasize the use of performance measures and computer analysis tools to prove the effectiveness of proposed systems in the design phase. Facility managers may then balance increased protection against the cost of implementation and risk mitigation, thereby enabling effective business decisions. Applications expected to benefit from these programs include corrections, law enforcement, counter-terrorism, critical infrastructure protection, financial and medical care fraud, industrial security, and border security.

  3. Review of EPRI Nuclear Human Factors Program

    Energy Technology Data Exchange (ETDEWEB)

    Hanes, L.F.; O`Brien, J.F. [Electric Power Research Institute, Palo Alto, CA (United States)

    1996-03-01

    The Electric Power Research Institute (EPRI) Human Factors Program, which is part of the EPRI Nuclear Power Group, was established in 1975. Over the years, the Program has changed emphasis based on the shifting priorities and needs of the commercial nuclear power industry. The Program has produced many important products that provide significant safety and economic benefits for EPRI member utilities. This presentation will provide a brief history of the Program and products. Current projects and products that have been released recently will be mentioned.

  4. Collaboration for cooperative work experience programs in biomedical engineering education.

    Science.gov (United States)

    Krishnan, Shankar

    2010-01-01

    Incorporating cooperative education modules as a segment of the undergraduate educational program is aimed to assist students in gaining real-life experience in the field of their choice. The cooperative work modules facilitate the students in exploring different realistic aspects of work processes in the field. The track records for cooperative learning modules are very positive. However, it is indeed a challenge for the faculty developing Biomedical Engineering (BME) curriculum to include cooperative work experience or internship requirements coupled with a heavy course load through the entire program. The objective of the present work is to develop a scheme for collaborative co-op work experience for the undergraduate training in the fast-growing BME programs. A few co-op/internship models are developed for the students pursuing undergraduate BME degree. The salient features of one co-op model are described. The results obtained support the proposed scheme. In conclusion, the cooperative work experience will be an invaluable segment in biomedical engineering education and an appropriate model has to be selected to blend with the overall training program.

  5. Advanced Human Factors Engineering Tool Technologies.

    Science.gov (United States)

    1987-03-20

    the mail and telephone surveys. The authors would also like to extend a special thanks to Mr. David Rose of the Naval Air Development Center for his...ADVANCED NUNAN FACTORS ENGINEERING TOOL TECHNOLOGIES 3/3 (U) CARLON ASSOCIATES INC FAIRFAX Yff S A FLEGER ET AL. UNCLRS 20 NAR B? DARI5-BS-C-NO64 WIL...34" ".--: :’-...2,,. ,..:,.- ,’-"-’:"- "’-::"-,2 ., ..,," ,.- ..’.-.-.’.-,-. : .....v. _ *’--..., ...-- ,,. - -.; , :¢ 4., 5 5 lPeter laines Mr. David M. Ilarrah

  6. Cooperative and human aspects of software engineering: CHASE 2010

    DEFF Research Database (Denmark)

    Dittrich, Yvonne; Sharp, Helen C.; Winschiers Theophilus, Heike;

    2010-01-01

    are required, to improve the creation and maintenance of software. The 3rd workshop on Cooperative and Human Aspects of Software Engineering held at the International Conference on Software Engineering continued the tradition from earlier workshops and provided a lively forum to discuss current developments...... and high quality research in the field. Further dissemination of research results will lead to an improvement of software development and deployment across the globe....

  7. Engineering

    National Research Council Canada - National Science Library

    Includes papers in the following fields: Aerospace Engineering, Agricultural Engineering, Chemical Engineering, Civil Engineering, Electrical Engineering, Environmental Engineering, Industrial Engineering, Materials Engineering, Mechanical...

  8. Cooperative and Human Aspects of Software Engineering (CHASE 2008)

    DEFF Research Database (Denmark)

    2008-01-01

    The CHASE 2008 workshop is concerned with exploring the cooperative and human aspects of software engineering, and providing a forum for discussing high-quality research. Accepted papers reflect diversity of the field of software engineering – ranging from requirements to testing, and from...... ethnographic research to experiments. Moreover, the background of attendees reflects the diversity of researchers in this domain, ranging from sociology to psychology, from informatics to software engineering. CHASE 1008 met its goals in presenting high-quality research and building community through a mixture...

  9. Cooperative and Human Aspects of Software Engineering (CHASE 2008)

    DEFF Research Database (Denmark)

    2008-01-01

    The CHASE 2008 workshop is concerned with exploring the cooperative and human aspects of software engineering, and providing a forum for discussing high-quality research. Accepted papers reflect diversity of the field of software engineering – ranging from requirements to testing, and from...... ethnographic research to experiments. Moreover, the background of attendees reflects the diversity of researchers in this domain, ranging from sociology to psychology, from informatics to software engineering. CHASE 1008 met its goals in presenting high-quality research and building community through a mixture...

  10. Interdisciplinary skills in architectural and engineering education programs

    DEFF Research Database (Denmark)

    Andersson, Niclas; Andersson, Pernille Hammar

    2006-01-01

    project. Besides, new and more integrated forms of co-operation between the various actors make the prevalent professional disciplines more ambiguous and it compels into a need for trans-professional skills among the actors. In contrast to the requirements for interdisciplinary skills, the educational...... training programmes of architects and engineers are traditionally characterised by strict disciplinary boundaries. Thus, the prevailing educational system is challenged to meet the demands for trans-professional skills within industry. The purpose of this paper is to outline some pedagogical prerequisites...... and requirements for reinforcement of the interdisciplinary skills within the architectural and engineering education programs as to face the challenges from industry. The study claims that the development of interdisciplinary skills should be regarded a pedagogical issue that can be accomplished by integrative...

  11. Plant-Derived Human Collagen Scaffolds for Skin Tissue Engineering

    Science.gov (United States)

    Willard, James J.; Drexler, Jason W.; Das, Amitava; Roy, Sashwati; Shilo, Shani; Shoseyov, Oded

    2013-01-01

    Tissue engineering scaffolds are commonly formed using proteins extracted from animal tissues, such as bovine hide. Risks associated with the use of these materials include hypersensitivity and pathogenic contamination. Human-derived proteins lower the risk of hypersensitivity, but possess the risk of disease transmission. Methods engineering recombinant human proteins using plant material provide an alternate source of these materials without the risk of disease transmission or concerns regarding variability. To investigate the utility of plant-derived human collagen (PDHC) in the development of engineered skin (ES), PDHC and bovine hide collagen were formed into tissue engineering scaffolds using electrospinning or freeze-drying. Both raw materials were easily formed into two common scaffold types, electrospun nonwoven scaffolds and lyophilized sponges, with similar architectures. The processing time, however, was significantly lower with PDHC. PDHC scaffolds supported primary human cell attachment and proliferation at an equivalent or higher level than the bovine material. Interleukin-1 beta production was significantly lower when activated THP-1 macrophages where exposed to PDHC electrospun scaffolds compared to bovine collagen. Both materials promoted proper maturation and differentiation of ES. These data suggest that PDHC may provide a novel source of raw material for tissue engineering with low risk of allergic response or disease transmission. PMID:23298216

  12. Advanced diesel engine component development program, tasks 4-14

    Science.gov (United States)

    Kaushal, Tony S.; Weber, Karen E.

    1994-11-01

    This report summarizes the Advanced Diesel Engine Component Development (ADECD) Program to develop and demonstrate critical technology needed to advance the heavy-duty low heat rejection engine concept. Major development activities reported are the design, analysis, and fabrication of monolithic ceramic components; vapor phase and solid film lubrication; electrohydraulic valve actuation; and high pressure common rail injection. An advanced single cylinder test bed was fabricated as a laboratory tool in studying these advanced technologies. This test bed simulates the reciprocator for a system having no cooling system, turbo compounding, Rankine bottoming cycle, common rail injection, and variable valve actuation to achieve fuel consumption of 160 g/kW-hr (.26 lb/hp-hr). The advanced concepts were successfully integrated into the test engine. All ceramic components met their functional and reliability requirements. The firedeck, cast-in-place ports, valves, valve guides, piston cap, and piston ring were made from silicon nitride. Breakthroughs required to implement a 'ceramic' engine included the fabrication of air-gap cylinder heads, elimination of compression gaskets, machining of ceramic valve seats within the ceramic firedeck, fabrication of cast-in-place ceramic port liners, implementation of vapor phase lubrication, and elimination of the engine coolant system. Silicon nitride valves were successfully developed to meet several production abuse test requirements and incorporated into the test bed with a ceramic valve guide and solid film lubrication. The ADECD cylinder head features ceramic port shields to increase insulation and exhaust energy recovery. The combustion chamber includes a ceramic firedeck and piston cap. The tribological challenge posed by top ring reversal temperatures of 550 C was met through the development of vapor phase lubrication using tricresyl phosphate at the ring-liner interface. A solenoid-controlled, variable valve actuation system

  13. Patient safety - the role of human factors and systems engineering.

    Science.gov (United States)

    Carayon, Pascale; Wood, Kenneth E

    2010-01-01

    Patient safety is a global challenge that requires knowledge and skills in multiple areas, including human factors and systems engineering. In this chapter, numerous conceptual approaches and methods for analyzing, preventing and mitigating medical errors are described. Given the complexity of healthcare work systems and processes, we emphasize the need for increasing partnerships between the health sciences and human factors and systems engineering to improve patient safety. Those partnerships will be able to develop and implement the system redesigns that are necessary to improve healthcare work systems and processes for patient safety.

  14. Use of Computers in Human Factors Engineering

    Science.gov (United States)

    1974-11-01

    SENSES (PHYSIOLOGY), THERMOPLASTIC RESINS, VISUAL ACUITY (U)R RESEARCH CONCERNS DETERMINATION OF THE INFORMATION PRESENTATION REQUIREMENTS OF HUMAN DATA...THE GEOMETRY OF THE wORK STATION, IS CURRENTLY BEING DEVELOPED. IT IS CALLED COMBIMAN, AN ACRONYM FOR COMPUTERIZED BIOMECHANICAL MAN- MODELo COMBIMAN

  15. Requirements engineering and program synthesis: Mutually exclusive or synergistic?

    Science.gov (United States)

    Lowry, M. R.

    2001-01-01

    There has often been a clash within the formal methods community between early life-cycle proponents such as the requirements engineering community and late life-cycle proponents such as the program synthesis community. This talk will first characterize these positions and their underlying assumptions, and then expose a common set of problems and approaches. The talk will then propose an integrated life-cycle framework, and expound on its potential benefits. Technical challenges to achieving this integrated life-cycle framework will be described, as well as some preliminary work towards that goal.

  16. Requirements engineering and program synthesis: Mutually exclusive or synergistic?

    Science.gov (United States)

    Lowry, M. R.

    2001-01-01

    There has often been a clash within the formal methods community between early life-cycle proponents such as the requirements engineering community and late life-cycle proponents such as the program synthesis community. This talk will first characterize these positions and their underlying assumptions, and then expose a common set of problems and approaches. The talk will then propose an integrated life-cycle framework, and expound on its potential benefits. Technical challenges to achieving this integrated life-cycle framework will be described, as well as some preliminary work towards that goal.

  17. Nuclear Human Resources Development Program using Educational Core Simulator

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Yu Sun; Hong, Soon Kwan [KHNP-CRI, Daejeon (Korea, Republic of)

    2015-10-15

    KHNP-CRI(Korea Hydro and Nuclear Power Co.-Central Research Institute) has redesigned the existing Core Simulator(CoSi) used as a sort of training tools for reactor engineers in operating nuclear power plant to support Nuclear Human Resources Development (NHRD) Program focusing on the nuclear department of Dalat university in Vietnam. This program has been supported by MOTIE in Korea and cooperated with KNA(Korea Nuclear Association for International Cooperation) and HYU(Hanyang University) for enhancing the nuclear human resources of potential country in consideration with Korean Nuclear Power Plant as a next candidate energy sources. KHNP-CRI has provided Edu-CoSi to Dalat University in Vietnam in order to support Nuclear Human Resources Development Program in Vietnam. Job Qualification Certificates Program in KHNP is utilized to design a training course for Vietnamese faculty and student of Dalat University. Successfully, knowhow on lecturing the ZPPT performance, training and maintaining Edu-CoSi hardware are transferred by several training courses which KHNP-CRI provides.

  18. Prediction of jet engine parameters for control design using genetic programming

    OpenAIRE

    Martínez-Arellano, G; Cant, R; Nolle, L

    2014-01-01

    The simulation of a jet engine behavior is widely used in many different aspects of the engine development and maintenance. Achieving high quality jet engine control systems requires the iterative use of these simulations to virtually test the performance of the engine avoiding any possible damage on the real engine. Jet engine simulations involve the use of mathematical models which are complex and may not always be available. This paper introduces an approach based on Genetic Programming (G...

  19. Accreditation of Spanish engineering programs, first experiences. The case of the Terrassa School of Engineering

    Directory of Open Access Journals (Sweden)

    Mª Dolores Álvarez

    2016-03-01

    Full Text Available The implementation of the European Space for Higher Education has entailed new requirements for Spanish Higher Education Programs. Regulations (RD 1393, 2007 stablish that university programs, in order to have official validity, must be submitted to an external evaluation process before their official implementation, denominated Validation, and to an ex-post process or Accreditation. Terrassa School of Engineering (EET was one of the first schools in Spain to adapt to the European Space for Higher Education, in the academic period 2009-10 and then, one of the first university institutions submitted to an accreditation process. In this communication, the important role of the Internal Quality Assurance System in the assessment of the school’s programs is exposed as well as the approach followed in the key steps of the process: Accreditation

  20. Engineering large animal models of human disease.

    Science.gov (United States)

    Whitelaw, C Bruce A; Sheets, Timothy P; Lillico, Simon G; Telugu, Bhanu P

    2016-01-01

    The recent development of gene editing tools and methodology for use in livestock enables the production of new animal disease models. These tools facilitate site-specific mutation of the genome, allowing animals carrying known human disease mutations to be produced. In this review, we describe the various gene editing tools and how they can be used for a range of large animal models of diseases. This genomic technology is in its infancy but the expectation is that through the use of gene editing tools we will see a dramatic increase in animal model resources available for both the study of human disease and the translation of this knowledge into the clinic. Comparative pathology will be central to the productive use of these animal models and the successful translation of new therapeutic strategies.

  1. Evolutionary programming as a platform for in silico metabolic engineering

    DEFF Research Database (Denmark)

    Patil, Kiran Raosaheb; Rocha, Isabel; Förster, Jochen

    2005-01-01

    are discussed. Conclusion We show that evolutionary programming enables solving large gene knockout problems in relatively short computational time. The proposed algorithm also allows the optimization of non-linear objective functions or incorporation of non-linear constraints and additionally provides a family......, and it is therefore interesting to develop new faster algorithms. Results In this study we report an evolutionary programming based method to rapidly identify gene deletion strategies for optimization of a desired phenotypic objective function. We illustrate the proposed method for two important design parameters...... in industrial fermentations, one linear and other non-linear, by using a genome-scale model of the yeast Saccharomyces cerevisiae. Potential metabolic engineering targets for improved production of succinic acid, glycerol and vanillin are identified and underlying flux changes for the predicted mutants...

  2. Finite Element Program Generator and Its Application in Engineering

    Institute of Scientific and Technical Information of China (English)

    WANShui; HUHong; CHENJian-pin

    2004-01-01

    A completely new finite element software, Finite ElementProgram Generator (FEPG), is introduced and its designing thought and organizing structure is presented.FEPG uses the method of components and the technique of artificial intelligence to generate finite element program automatically by a computer according to the general principles of mathematic and internal rules of finite element method,as is similar to the deduction of mathematics.FEPG breaks through the limitation of present finite element software,which only applies to special discipline,while FEPG is suitable for all kinds of differential equations solved by finite element method.Now FEPG has been applied to superconductor research,electromagnetic field study,petroleum exploration,transportation,structure engineering,water conservancy,ship mechanics, solid-liquid coupling problems and liquid dynamics,etc.in China.

  3. Genetically engineered mouse models and human osteosarcoma

    Directory of Open Access Journals (Sweden)

    Ng Alvin JM

    2012-10-01

    Full Text Available Abstract Osteosarcoma is the most common form of bone cancer. Pivotal insight into the genes involved in human osteosarcoma has been provided by the study of rare familial cancer predisposition syndromes. Three kindreds stand out as predisposing to the development of osteosarcoma: Li-Fraumeni syndrome, familial retinoblastoma and RecQ helicase disorders, which include Rothmund-Thomson Syndrome in particular. These disorders have highlighted the important roles of P53 and RB respectively, in the development of osteosarcoma. The association of OS with RECQL4 mutations is apparent but the relevance of this to OS is uncertain as mutations in RECQL4 are not found in sporadic OS. Application of the knowledge or mutations of P53 and RB in familial and sporadic OS has enabled the development of tractable, highly penetrant murine models of OS. These models share many of the cardinal features associated with human osteosarcoma including, importantly, a high incidence of spontaneous metastasis. The recent development of these models has been a significant advance for efforts to improve our understanding of the genetics of human OS and, more critically, to provide a high-throughput genetically modifiable platform for preclinical evaluation of new therapeutics.

  4. Developing Systems Engineering Graduate Programs Aligned to the Body of Knowledge and Curriculum to Advance Systems Engineering (BKCASE(TM)) Guidelines

    Science.gov (United States)

    2011-06-01

    AND SUBTITLE Developing Systems Engineering Graduate Programs Aligned to the Body of Knowledge and Curriculum to Advance Systems Engineering (BKCASETM...Engineering Graduate Programs Aligned to the Body of Knowledge and Curriculum to Advance Systems Engineering (BKCASETM) Guidelines Abstract The Body...develop new systems engineering graduate programs . One method is to develop the program within an existing department by combining new curriculum into a

  5. Teaching Radioactive Waste Management in an Undergraduate Engineering Program - 13269

    Energy Technology Data Exchange (ETDEWEB)

    Ikeda, Brian M. [Faculty of Energy Systems and Nuclear Science, University of Ontario Institute of Technology, 2000 Simcoe Street North, Oshawa, Ontario L1H 7K4 (Canada)

    2013-07-01

    The University of Ontario Institute of Technology is Ontario's newest university and the only one in Canada that offers an accredited Bachelor of Nuclear Engineering (Honours) degree. The nuclear engineering program consists of 48 full-semester courses, including one on radioactive waste management. This is a design course that challenges young engineers to develop a fundamental understanding of how to manage the storage and disposal of various types and forms of radioactive waste, and to recognize the social consequences of their practices and decisions. Students are tasked with developing a major project based on an environmental assessment of a simple conceptual design for a waste disposal facility. They use collaborative learning and self-directed exploration to gain the requisite knowledge of the waste management system. The project constitutes 70% of their mark, but is broken down into several small components that include, an environmental assessment comprehensive study report, a technical review, a facility design, and a public defense of their proposal. Many aspects of the project mirror industry team project situations, including the various levels of participation. The success of the students is correlated with their engagement in the project, the highest final examination scores achieved by students with the strongest effort in the project. (authors)

  6. Development of Key Performance Indicators for the Engineering Technology Education Programs in Taiwan

    Science.gov (United States)

    Lee, Lung-Sheng; Lai, Chun-Chin

    2004-01-01

    In comparison with engineering, engineering technology is more practical and purposeful. The engineering technology education programs in Taiwan have been mainly offered in 56 universities/colleges of technology (UTs/CTs) and are anticipated to continuously improve their performance to prepare quality engineering technologists. However, it is…

  7. Math and science education programs from the Idaho National Engineering Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    1991-01-01

    This booklet reviews math and science education programs at the Idaho National Engineering Laboratory (INEL). The programs can be categorized into six groups: teacher programs; science laboratories for students; student programs; education outreach programs; INEL Public Affairs Office; and programs for college faculty and students.

  8. Sodium Heat Engine Development Program. Phase 1, Final report

    Energy Technology Data Exchange (ETDEWEB)

    Singh, J.P.; Kupperman, D.S.; Majumdar, S.; Dorris, S.; Gopalsami, N.; Dieckman, S.L.; Jaross, R.A.; Johnson, D.L.; Gregar, J.S.; Poeppel, R.B.; Raptis, A.C.; Valentin, R.A.

    1992-01-01

    The Sodium Heat Engine (SHE) is an efficient thermoelectric conversion device which directly generates electricity from a thermally regenerative electrochemical cell that relies on the unique conduction properties of {beta}{double_prime}-alumina solid electrolyte (BASE). Laboratory models of a variety of SHE devices have demonstrated the feasibility and efficiency of the system, engineering development of large prototype devices has been slowed by a series of materials and fabrication problems. Failure of the electrolyte tubes has been a recurring problem and a number of possible causes have been postulated. To address these issues, a two-phase engineering development program was undertaken. This report summarizes the final results of the first phase of the program, which included extensive materials characterization activities, a study of applicable nondestructive evaluation methods, an investigation of possible stress states that would contribute to fracture, and certain operational issues associated with the electromagnetic pumps used in the SHE prototype. Mechanical and microstructural evaluation of commercially obtained BASE tubes revealed that they should be adequate for SHE applications and that sodium exposure produced no appreciable deleterious strength effects. Processing activities to produce a more uniform and smaller grain size for the BASE tubes were completed using isostatic pressing, extrusion, and slip casting. Green tubes were sintered by conventional and microwave plasma methods. Of particular interest is the residual stress state in the BASE tubes, and both analysis and nondestructive evaluation methods were employed to evaluate these stresses. X-ray and neutron diffraction experiments were performed to determine the bulk residual stresses in commercially fabricated BASE tubes; however, tube-to-tube variations and variations among the various methods employed did not allow formulation of a definitive definition of the as-fabricated stress state.

  9. Human Factors Engineering and School Furniture: A Circular Odyssey.

    Science.gov (United States)

    Lane, Kenneth E.; Richardson, Michael D.

    1993-01-01

    A search reveals only six articles that concern human-factors engineering as it relates to student furniture. Contacts with five school-furniture manufacturers disclose that designs were basically unaltered for years and are claimed to reflect what schools want in furniture. Proposes recommendations to design and secure furniture to meet students'…

  10. Human Systems Engineering: A Leadership Model for Collaboration and Change.

    Science.gov (United States)

    Clark, Karen L.

    Human systems engineering (HSE) was created to introduce a new way of viewing collaboration. HSE emphasizes the role of leaders who welcome risk, commit to achieving positive change, and help others achieve change. The principles of HSE and its successful application to the collaborative process were illustrated through a case study representing a…

  11. Training human mesenchymal stromal cells for bone tissue engineering applications

    NARCIS (Netherlands)

    Doorn, J.

    2012-01-01

    Human mesenchymal stromal cells (hMSCs) are an interesting source for cell therapies and tissue engineering applications, because these cells are able to differentiate into various target tissues, such as bone, cartilage, fat and endothelial cells. In addition, they secrete a wide array of growth fa

  12. Human Research Program: 2012 Fiscal Year Annual Report

    Science.gov (United States)

    Effenhauser, Laura

    2012-01-01

    Crew health and performance are critical to successful human exploration beyond low Earth orbit. Risks to health and performance include physiologic effects from radiation, hypogravity, and planetary environments, as well as unique challenges in medical treatment, human factors, and support of behavioral health. The scientists and engineers of the Human Research Program (HRP) investigate and reduce the greatest risks to human health and performance, and provide essential countermeasures and technologies for human space exploration. In its seventh year of operation, the HRP continued to refine its management architecture of evidence, risks, gaps, tasks, and deliverables. Experiments continued on the International Space Station (ISS), on the ground in analog environments that have features similar to those of spaceflight, and in laboratory environments. Data from these experiments furthered the understanding of how the space environment affects the human system. These research results contributed to scientific knowledge and technology developments that address the human health and performance risks. As shown in this report, HRP has made significant progress toward developing medical care and countermeasure systems for space exploration missions which will ultimately reduce risks to crew health and performance.

  13. Romanian MRE Rocket Engines Program - An Early Endeavor

    Science.gov (United States)

    Rugescu, R. E.

    2002-01-01

    (MRE) was initiated in the years '60 of the past century at the Chair of Aerospace Sciences "Elie Carafoli" from the "Politehnica" University in Bucharest (PUB). Consisting of theoretical and experimental investigations in the form of computational methods and technological solutions for small size MRE-s and the concept of the test stand for these engines, the program ended in the construction of the first Romanian liquid rocket motors. Hermann Oberth and Dorin Pavel, were known from 1923, no experimental practice was yet tempted, at the time level of 1960. It was the intention of the developers at PUB to cover this gap and initiate a feasible, low-cost, demonstrative program of designing and testing experimental models of MRE. The research program was oriented towards future development of small size space carrier vehicles for scientific applications only, as an independent program with no connection to other defense programs imagined by the authorities in Bucharest, at that time. Consequently the entire financial support was assured by "Politehnica" university. computerized methods in the thermochemistry of heterogeneous combustion, for both steady and unsteady flows with chemical reactions and two phase flows. The research was gradually extended to the production of a professional CAD program for steady-state heat transfer simulations and the loading capacity analyses of the double wall, cooled thrust chamber. The resulting computer codes were run on a 360-30 IMB machine, beginning in 1968. Some of the computational methods were first exposed at the 9th International Conference on Applied Mechanics, held in Bucharest between June 23-27, 1969. hot testing of a series of storable propellant, variable thrust, variable geometry, liquid rocket motors, with a maximal thrust of 200N. A remotely controlled, portable test bad, actuated either automatically or manually and consisting of a 6-modules construction was built for this motor series, with a simple 8 analog

  14. Integrating electron microscopy into nanoscience and materials engineering programs

    Science.gov (United States)

    Cormia, Robert D.; Oye, Michael M.; Nguyen, Anh; Skiver, David; Shi, Meng; Torres, Yessica

    2014-10-01

    Preparing an effective workforce in high technology is the goal of both academic and industry training, and has been the engine that drives innovation and product development in the United States for over a century. During the last 50 years, technician training has comprised a combination of two-year academic programs, internships and apprentice training, and extensive On-the-Job Training (OJT). Recently, and especially in Silicon Valley, technicians have four-year college degrees, as well as relevant hands-on training. Characterization in general, and microscopy in particular, is an essential tool in process development, manufacturing and QA/QC, and failure analysis. Training for a broad range of skills and practice is challenging, especially for community colleges. Workforce studies (SRI/Boeing) suggest that even four year colleges often do not provide the relevant training and experience in laboratory skills, especially design of experiments and analysis of data. Companies in high-tech further report difficulty in finding skilled labor, especially with industry specific experience. Foothill College, in partnership with UCSC, SJSU, and NASA-Ames, has developed a microscopy training program embedded in a research laboratory, itself a partnership between university and government, providing hands-on experience in advanced instrumentation, experimental design and problem solving, with real-world context from small business innovators, in an environment called `the collaboratory'. The program builds on AFM-SEM training at Foothill, and provides affordable training in FE-SEM and TEM through a cost recovery model. In addition to instrument and engineering training, the collaboratory also supports academic and personal growth through a multiplayer social network of students, faculty, researchers, and innovators.

  15. 1996 LMITCO environmental monitoring program report for the Idaho National Engineering and Environmental Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-09-01

    This report describes the calendar year 1996 environmental surveillance and compliance monitoring activities of the Lockheed Martin Idaho Technologies Company Environmental Monitoring Program performed at the Idaho National Engineering and Environmental Laboratory (INEEL). Results of sampling performed by the Radiological Environmental Surveillance, Site Environmental Surveillance, Drinking Water, Effluent Monitoring, Storm Water Monitoring, Groundwater Monitoring, and Special Request Monitoring Programs are included in this report. The primary purposes of the surveillance and monitoring activities are to evaluate environmental conditions, to provide and interpret data, to verify compliance with applicable regulations or standards, and to ensure protection of human health and the environment. This report compares 1996 data with program-specific regulatory guidelines and past data to evaluate trends.

  16. Computer program for a four-cylinder-Stirling-engine controls simulation

    Science.gov (United States)

    Daniels, C. J.; Lorenzo, C. F.

    1982-06-01

    A four cylinder Stirling engine, transient engine simulation computer program is presented. The program is intended for controls analysis. The associated engine model was simplified to shorten computer calculation time. The model includes engine mechanical drive dynamics and vehicle load effects. The computer program also includes subroutines that allow: (1) acceleration of the engine by addition of hydrogen to the system, and (2) braking of the engine by short circuiting of the working spaces. Subroutines to calculate degraded engine performance (e.g., due to piston ring and piston rod leakage) are provided. Input data required to run the program are described and flow charts are provided. The program is modular to allow easy modification of individual routines. Examples of steady state and transient results are presented.

  17. Curriculum Development Based on the Big Picture Assessment of the Mechanical Engineering Program

    Science.gov (United States)

    Sabri, Mohd Anas Mohd; Khamis, Nor Kamaliana; Tahir, Mohd Faizal Mat; Wahid, Zaliha; Kamal, Ahmad; Ihsan, Ariffin Mohd; Sulong, Abu Bakar; Abdullah, Shahrum

    2013-01-01

    One of the major concerns of the Engineering Accreditation Council (EAC) is the need for an effective monitoring and evaluation of program outcome domains that can be associated with courses taught under the Mechanical Engineering program. However, an effective monitoring method that can determine the results of each program outcome using Bloom's…

  18. HOW DO RADIOLOGISTS USE THE HUMAN SEARCH ENGINE?

    Science.gov (United States)

    Wolfe, Jeremy M; Evans, Karla K; Drew, Trafton; Aizenman, Avigael; Josephs, Emilie

    2016-06-01

    Radiologists perform many 'visual search tasks' in which they look for one or more instances of one or more types of target item in a medical image (e.g. cancer screening). To understand and improve how radiologists do such tasks, it must be understood how the human 'search engine' works. This article briefly reviews some of the relevant work into this aspect of medical image perception. Questions include how attention and the eyes are guided in radiologic search? How is global (image-wide) information used in search? How might properties of human vision and human cognition lead to errors in radiologic search?

  19. Incremental Scheduling Engines for Human Exploration of the Cosmos

    Science.gov (United States)

    Jaap, John; Phillips, Shaun

    2005-01-01

    As humankind embarks on longer space missions farther from home, the requirements and environments for scheduling the activities performed on these missions are changing. As we begin to prepare for these missions it is appropriate to evaluate the merits and applicability of the different types of scheduling engines. Scheduling engines temporally arrange tasks onto a timeline so that all constraints and objectives are met and resources are not overbooked. Scheduling engines used to schedule space missions fall into three general categories: batch, mixed-initiative, and incremental. This paper presents an assessment of the engine types, a discussion of the impact of human exploration of the moon and Mars on planning and scheduling, and the applicability of the different types of scheduling engines. This paper will pursue the hypothesis that incremental scheduling engines may have a place in the new environment; they have the potential to reduce cost, to improve the satisfaction of those who execute or benefit from a particular timeline (the customers), and to allow astronauts to plan their own tasks and those of their companion robots.

  20. Systems Engineering and Program Management. Trends and Costs for Aircraft and Guided Weapons Programs

    Science.gov (United States)

    2006-01-01

    Project AIR FORCE PCA Physical Configuration Audit P&D Production and Deployment PDR Preliminary Design Review P3I Preplanned Product Improvement PIN ...Program Management SEPM LOT Lot Cost of SE/PM (in production) SEPM UC Unit Cost of SE/PM (in production) SFR System Functional Review ii SE/PM...perform as intended, without a mission critical failure , for a specified period of time. Maintainability engineers are concerned with the resource re

  1. Online-BSEE (Online Bachelor of Science in Electrical Engineering): An Asynchronous Online Electrical Engineering Degree Program with Laboratory

    Science.gov (United States)

    Tang, Wendy; Westgate, Charles; Liu, Pao-Lo; Gouzman, Michael

    2014-01-01

    The Online Bachelor of Science in Electrical Engineering is a collaborative effort among three University Centers at SUNY (State University of New York), namely Stony Brook, Binghamton, and Buffalo. The program delivers the complete electrical engineering curriculum at the bachelor level to students online and asynchronously. Students, however,…

  2. VHTR engineering design study: intermediate heat exchanger program. Final report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1976-11-01

    The work reported is the result of a follow-on program to earlier Very High Temperature Reactor (VHTR) studies. The primary use of the VHTR is to provide heat for various industrial processes, such as hydrocarbon reforming and coal gasification. For many processes the use of an intermediate heat transfer barrier between the reactor coolant and the process is desirable; for some processes it is mandatory. Various intermediate heat exchanger (IHX) concepts for the VHTR were investigated with respect to safety, cost, and engineering design considerations. The reference processes chosen were steam-hydrocarbon reforming, with emphasis on the chemical heat pipe, and steam gasification of coal. The study investigates the critically important area of heat transfer between the reactor coolant, helium, and the various chemical processes.

  3. The Event Coordination Notation: Execution Engine and Programming Framework

    DEFF Research Database (Denmark)

    Kindler, Ekkart

    2012-01-01

    that was written manually. In this paper, we rephrase the main concepts of ECNO. The focus of this paper, however, is on the architecture of the ECNO execution engine and its programming framework. We will show how this framework allows us to integrate ECNO with object-oriented models, how it works without any......ECNO (Event Coordination Notation) is a notation for modelling the behaviour of a software system on top of some object-oriented data model. ECNO has two main objectives: On the one hand, ECNO should allow modelling the behaviour of a system on the domain level; on the other hand, it should...... be possible to completely generate code from ECNO and the underlying object-oriented domain models. Today, there are several approaches that would allow to do this. But, most of them would require that the data models and the behaviour models are using the same technology and the code is generated together...

  4. A phenomenographic study of students' experiences with transition from pre-college engineering programs to first-year engineering

    Science.gov (United States)

    Salzman, Noah

    Recent national dialogues on the importance of preparing more students for careers in Science, Technology, Engineering, and Mathematics has driven the development of formal and informal learning opportunities for children and adolescents to explore engineering. Despite the growth of these programs, relatively little research exists on how participation in these programs affects students who choose to pursue further study in engineering. The present study addressed this gap through an exploration of the different ways that First-Year Engineering students experience the transition from pre-college engineering to undergraduate engineering studies. Given the focus of this research on students' experiences, phenomenography was chosen to explore the phenomenon of transition from pre-college to first-year engineering at a large, public Midwestern university. This facilitated understanding the range of variation in the ways that students experienced this transition. Twenty-two students with different amounts of participation in a variety of different engineering programs were selected to be interviewed using a purposeful maximum variation sampling strategy. The interviews were guided by a semi-structured interview protocol that encouraged the participants to reflect on their pre-college engineering experiences, their experiences in First-Year Engineering, and the transition between the two domains. The interviews were analyzed using phenomenographic methods to develop an outcome space consisting of five qualitatively different but related ways of experiencing the transition from pre-college to First-Year Engineering. These categories of description included Foreclosure, Frustration, Tedium, Connection, and Engaging Others. With the exception of the first category which was characterized by a lack of passion and commitment to engineering, the remaining four categories formed a hierarchical relationship representing increasing integration in First-Year Engineering. The

  5. Managing PBL difficulties in an industrial engineering and management program

    Energy Technology Data Exchange (ETDEWEB)

    Alves, A.; Sousa, R.; Moreira, F.; Carvalho, M.A.; Cardoso, E.; Pimenta, P.; Malheiro, T.; Brito, I.; Fernandes, S.; Mesquita, D.

    2016-07-01

    Project-Based Learning (PBL) is considered to be an active learning methodology which can be used to develop both technical and transversal competences in engineering programs. This methodology demands a great deal of work effort from the students and also from the teachers and it requires a meticulous plan and a well-managed project as well. These activities go far beyond the normal activities in traditional lectures, enabling to outpace the difficulties that spur along the way that may be both complex and demotivating. This methodology has been implemented in the Integrated Master Degree on Industrial Engineering and Management (IEM), at one public university in Portugal, since the 2004/2005 academic year. The aim of this paper is to identify and discuss the main difficulties of the implementation of PBL, mainly from the teachers’ perspectives. Additionally, some effective strategies will be recommended to overcome such difficulties. Design/methodology/approach: The perceptions of the teachers were collected through a survey based on six main themes. The participants in the study include eight teachers from the five courses of the first semester of the first year of the IEM program involved in the 2012/2013 and 2013/2014 editions. Findings: Integration of courses in the project; student assessment; growing number of students in each team and the need of physical spaces for them; and compartmentalized knowledge has emerged as the main difficulties. To overcome these difficulties some key strategies were recommended. Originality/value: A new perspective based on course teachers' views and experiences will deepen the understanding of the problems and provide inputs for the development of strategies that may improve the effectiveness of PBL and introduce changes for its successful implementation. These strategies are intended to be transferable to other contexts, as most of the problems and constraints are common to other active learning approaches. (Author)

  6. Managing PBL difficulties in an industrial engineering and management program

    Directory of Open Access Journals (Sweden)

    Anabela Alves

    2016-08-01

    Full Text Available Purpose: Project-Based Learning (PBL is considered to be an active learning methodology which can be used to develop both technical and transversal competences in engineering programs. This methodology demands a great deal of work effort from the students and also from the teachers and it requires a meticulous plan and a well-managed project as well. These activities go far beyond the normal activities in traditional lectures, enabling to outpace the difficulties that spur along the way that may be both complex and demotivating. This methodology has been implemented in the Integrated Master Degree on Industrial Engineering and Management (IEM, at one public university in Portugal, since the 2004/2005 academic year. The aim of this paper is to identify and discuss the main difficulties of the implementation of PBL, mainly from the teachers’ perspectives. Additionally, some effective strategies will be recommended to overcome such difficulties. Design/methodology/approach: The perceptions of the teachers were collected through a survey based on six main themes. The participants in the study include eight teachers from the five courses of the first semester of the first year of the IEM program involved in the 2012/2013 and 2013/2014 editions. Findings: Integration of courses in the project; student assessment; growing number of students in each team and the need of physical spaces for them; and compartmentalized knowledge has emerged as the main difficulties. To overcome these difficulties some key strategies were recommended. Originality/value: A new perspective based on course teachers' views and experiences will deepen the understanding of the problems and provide inputs for the development of strategies that may improve the effectiveness of PBL and introduce changes for its successful implementation. These strategies are intended to be transferable to other contexts, as most of the problems and constraints are common to other active learning

  7. Site-Specific Genome Engineering in Human Pluripotent Stem Cells

    Directory of Open Access Journals (Sweden)

    Sylvia Merkert

    2016-06-01

    Full Text Available The possibility to generate patient-specific induced pluripotent stem cells (iPSCs offers an unprecedented potential of applications in clinical therapy and medical research. Human iPSCs and their differentiated derivatives are tools for diseases modelling, drug discovery, safety pharmacology, and toxicology. Moreover, they allow for the engineering of bioartificial tissue and are promising candidates for cellular therapies. For many of these applications, the ability to genetically modify pluripotent stem cells (PSCs is indispensable, but efficient site-specific and safe technologies for genetic engineering of PSCs were developed only recently. By now, customized engineered nucleases provide excellent tools for targeted genome editing, opening new perspectives for biomedical research and cellular therapies.

  8. Site-Specific Genome Engineering in Human Pluripotent Stem Cells.

    Science.gov (United States)

    Merkert, Sylvia; Martin, Ulrich

    2016-06-24

    The possibility to generate patient-specific induced pluripotent stem cells (iPSCs) offers an unprecedented potential of applications in clinical therapy and medical research. Human iPSCs and their differentiated derivatives are tools for diseases modelling, drug discovery, safety pharmacology, and toxicology. Moreover, they allow for the engineering of bioartificial tissue and are promising candidates for cellular therapies. For many of these applications, the ability to genetically modify pluripotent stem cells (PSCs) is indispensable, but efficient site-specific and safe technologies for genetic engineering of PSCs were developed only recently. By now, customized engineered nucleases provide excellent tools for targeted genome editing, opening new perspectives for biomedical research and cellular therapies.

  9. Development of Nuclear Engineering Educational Program at Ibaraki University with Regional Collaboration

    Science.gov (United States)

    Matsumura, Kunihito; Kaminaga, Fumito; Kanto, Yasuhiro; Tanaka, Nobuatsu; Saigusa, Mikio; Kikuchi, Kenji; Kurumada, Akira

    The College of Engineering, Ibaraki University is located at the Hitachi city, in the north part of Ibaraki prefecture. Hitachi and Tokai areas are well known as concentration of advanced technology center of nuclear power research organizations. By considering these regional advantages, we developed a new nuclear engineering educational program for students in the Collage of Engineering and The Graduate School of Science and Engineering of Ibaraki University. The program is consisted of the fundamental lectures of nuclear engineering and nuclear engineering experiments. In addition, several observation learning programs by visiting cooperative organizations are also included in the curriculum. In this paper, we report about the progress of the new educational program for nuclear engineering in Ibaraki University.

  10. Human factors engineering report for the cold vacuum drying facility

    Energy Technology Data Exchange (ETDEWEB)

    IMKER, F.W.

    1999-06-30

    The purpose of this report is to present the results and findings of the final Human Factors Engineering (HFE) technical analysis and evaluation of the Cold Vacuum Drying Facility (CVDF). Ergonomics issues are also addressed in this report, as appropriate. This report follows up and completes the preliminary work accomplished and reported by the Preliminary HFE Analysis report (SNF-2825, Spent Nuclear Fuel Project Cold Vacuum Drying Facility Human Factors Engineering Analysis: Results and Findings). This analysis avoids redundancy of effort except for ensuring that previously recommended HFE design changes have not affected other parts of the system. Changes in one part of the system may affect other parts of the system where those changes were not applied. The final HFE analysis and evaluation of the CVDF human-machine interactions (HMI) was expanded to include: the physical work environment, human-computer interface (HCI) including workstation and software, operator tasks, tools, maintainability, communications, staffing, training, and the overall ability of humans to accomplish their responsibilities, as appropriate. Key focal areas for this report are the process bay operations, process water conditioning (PWC) skid, tank room, and Central Control Room operations. These key areas contain the system safety-class components and are the foundation for the human factors design basis of the CVDF.

  11. A HUMAN FACTORS ENGINEERING PROCESS TO SUPPORT HUMAN-SYSTEM INTERFACE DESIGN IN CONTROL ROOM MODERNIZATION

    Energy Technology Data Exchange (ETDEWEB)

    Kovesdi, C.; Joe, J.; Boring, R.

    2017-05-01

    The primary objective of the United States (U.S.) Department of Energy (DOE) Light Water Reactor Sustainability (LWRS) program is to sustain operation of the existing commercial nuclear power plants (NPPs) through a multi-pathway approach in conducting research and development (R&D). The Advanced Instrumentation, Information, and Control (II&C) System Technologies pathway conducts targeted R&D to address aging and reliability concerns with legacy instrumentation and control (I&C) and other information systems in existing U.S. NPPs. Control room modernization is an important part following this pathway, and human factors experts at Idaho National Laboratory (INL) have been involved in conducting R&D to support migration of new digital main control room (MCR) technologies from legacy analog and legacy digital I&C. This paper describes a human factors engineering (HFE) process that supports human-system interface (HSI) design in MCR modernization activities, particularly with migration of old digital to new digital I&C. The process described in this work is an expansion from the LWRS Report INL/EXT-16-38576, and is a requirements-driven approach that aligns with NUREG-0711 requirements. The work described builds upon the existing literature by adding more detail around key tasks and decisions to make when transitioning from HSI Design into Verification and Validation (V&V). The overall objective of this process is to inform HSI design and elicit specific, measurable, and achievable human factors criteria for new digital technologies. Upon following this process, utilities should have greater confidence with transitioning from HSI design into V&V.

  12. Human Factors Engineering Requirements for the International Space Station - Successes and Challenges

    Science.gov (United States)

    Whitmore, M.; Blume, J.

    2003-01-01

    Advanced technology coupled with the desire to explore space has resulted in increasingly longer human space missions. Indeed, any exploration mission outside of Earth's neighborhood, in other words, beyond the moon, will necessarily be several months or even years. The International Space Station (ISS) serves as an important advancement toward executing a successful human space mission that is longer than a standard trip around the world or to the moon. The ISS, which is a permanently occupied microgravity research facility orbiting the earth, will support missions four to six months in duration. In planning for the ISS, the NASA developed an agency-wide set of human factors standards for the first time in a space exploration program. The Man-Systems Integration Standard (MSIS), NASA-STD-3000, a multi-volume set of guidelines for human-centered design in microgravity, was developed with the cooperation of human factors experts from various NASA centers, industry, academia, and other government agencies. The ISS program formed a human factors team analogous to any major engineering subsystem. This team develops and maintains the human factors requirements regarding end-to-end architecture design and performance, hardware and software design requirements, and test and verification requirements. It is also responsible for providing program integration across all of the larger scale elements, smaller scale hardware, and international partners.

  13. DRUMS: a human disease related unique gene mutation search engine.

    Science.gov (United States)

    Li, Zuofeng; Liu, Xingnan; Wen, Jingran; Xu, Ye; Zhao, Xin; Li, Xuan; Liu, Lei; Zhang, Xiaoyan

    2011-10-01

    With the completion of the human genome project and the development of new methods for gene variant detection, the integration of mutation data and its phenotypic consequences has become more important than ever. Among all available resources, locus-specific databases (LSDBs) curate one or more specific genes' mutation data along with high-quality phenotypes. Although some genotype-phenotype data from LSDB have been integrated into central databases little effort has been made to integrate all these data by a search engine approach. In this work, we have developed disease related unique gene mutation search engine (DRUMS), a search engine for human disease related unique gene mutation as a convenient tool for biologists or physicians to retrieve gene variant and related phenotype information. Gene variant and phenotype information were stored in a gene-centred relational database. Moreover, the relationships between mutations and diseases were indexed by the uniform resource identifier from LSDB, or another central database. By querying DRUMS, users can access the most popular mutation databases under one interface. DRUMS could be treated as a domain specific search engine. By using web crawling, indexing, and searching technologies, it provides a competitively efficient interface for searching and retrieving mutation data and their relationships to diseases. The present system is freely accessible at http://www.scbit.org/glif/new/drums/index.html.

  14. Cooperative and Human Aspects of Software Engineering (CHASE 2010)

    DEFF Research Database (Denmark)

    Dittrich, Yvonne; De Souza, Cleidson; Korpela, Mikko

    2010-01-01

    Software is created by people---software engineers---working in varied environments, under various conditions. Thus understanding cooperative and human aspect of software development is crucial to comprehend how methods and tools are used, and thereby improving the creation and maintenance...... research on human and cooperative aspects of software engineering. We aim at providing both a meeting place for the growing community and the possibility for researchers interested in joining the field to present their work in progress and get an overview over the field....... of software. Inspired by the hosting country's concept of co-responsibility -- ubuntu -- we especially invited contributions that address community-based development like open source development and sustainability of ICT eco-systems. The goal of this workshop is to provide a forum for discussing high quality...

  15. Cooperative and Human Aspects of Software Engineering (CHASE 2010)

    DEFF Research Database (Denmark)

    Dittrich, Yvonne; De Souza, Cleidson; Korpela, Mikko

    2010-01-01

    of software. Inspired by the hosting country's concept of co-responsibility -- ubuntu -- we especially invited contributions that address community-based development like open source development and sustainability of ICT eco-systems. The goal of this workshop is to provide a forum for discussing high quality......Software is created by people---software engineers---working in varied environments, under various conditions. Thus understanding cooperative and human aspect of software development is crucial to comprehend how methods and tools are used, and thereby improving the creation and maintenance...... research on human and cooperative aspects of software engineering. We aim at providing both a meeting place for the growing community and the possibility for researchers interested in joining the field to present their work in progress and get an overview over the field....

  16. Computer aided systems human engineering: A hypermedia tool

    Science.gov (United States)

    Boff, Kenneth R.; Monk, Donald L.; Cody, William J.

    1992-01-01

    The Computer Aided Systems Human Engineering (CASHE) system, Version 1.0, is a multimedia ergonomics database on CD-ROM for the Apple Macintosh II computer, being developed for use by human system designers, educators, and researchers. It will initially be available on CD-ROM and will allow users to access ergonomics data and models stored electronically as text, graphics, and audio. The CASHE CD-ROM, Version 1.0 will contain the Boff and Lincoln (1988) Engineering Data Compendium, MIL-STD-1472D and a unique, interactive simulation capability, the Perception and Performance Prototyper. Its features also include a specialized data retrieval, scaling, and analysis capability and the state of the art in information retrieval, browsing, and navigation.

  17. Concise review: Human cell engineering: cellular reprogramming and genome editing.

    Science.gov (United States)

    Mali, Prashant; Cheng, Linzhao

    2012-01-01

    Cell engineering is defined here as the collective ability to both reset and edit the genome of a mammalian cell. Until recently, this had been extremely challenging to achieve as nontransformed human cells are significantly refractory to both these processes. The recent success in reprogramming somatic cells into induced pluripotent stem cells that are self-renewable in culture, coupled with our increasing ability to effect precise and predesigned genomic editing, now readily permits cellular changes at both the genetic and epigenetic levels. These dual capabilities also make possible the generation of genetically matched, disease-free stem cells from patients for regenerative medicine. The objective of this review is to summarize the key enabling developments on these two rapidly evolving research fronts in human cell engineering, highlight unresolved issues, and outline potential future research directions.

  18. A general sequence processing and analysis program for protein engineering.

    Science.gov (United States)

    Stafford, Ryan L; Zimmerman, Erik S; Hallam, Trevor J; Sato, Aaron K

    2014-10-27

    Protein engineering projects often amass numerous raw DNA sequences, but no readily available software combines sequence processing and activity correlation required for efficient lead identification. XLibraryDisplay is an open source program integrated into Microsoft Excel for Windows that automates batch sequence processing via a simple step-by-step, menu-driven graphical user interface. XLibraryDisplay accepts any DNA template which is used as a basis for trimming, filtering, translating, and aligning hundreds to thousands of sequences (raw, FASTA, or Phred PHD file formats). Key steps for library characterization through lead discovery are available including library composition analysis, filtering by experimental data, graphing and correlating to experimental data, alignment to structural data extracted from PDB files, and generation of PyMOL visualization scripts. Though larger data sets can be handled, the program is best suited for analyzing approximately 10 000 or fewer leads or naïve clones which have been characterized using Sanger sequencing and other experimental approaches. XLibraryDisplay can be downloaded for free from sourceforge.net/projects/xlibrarydisplay/ .

  19. Tissue engineered humanized bone supports human hematopoiesis in vivo.

    Science.gov (United States)

    Holzapfel, Boris M; Hutmacher, Dietmar W; Nowlan, Bianca; Barbier, Valerie; Thibaudeau, Laure; Theodoropoulos, Christina; Hooper, John D; Loessner, Daniela; Clements, Judith A; Russell, Pamela J; Pettit, Allison R; Winkler, Ingrid G; Levesque, Jean-Pierre

    2015-08-01

    Advances in tissue-engineering have resulted in a versatile tool-box to specifically design a tailored microenvironment for hematopoietic stem cells (HSCs) in order to study diseases that develop within this setting. However, most current in vivo models fail to recapitulate the biological processes seen in humans. Here we describe a highly reproducible method to engineer humanized bone constructs that are able to recapitulate the morphological features and biological functions of the HSC niches. Ectopic implantation of biodegradable composite scaffolds cultured for 4 weeks with human mesenchymal progenitor cells and loaded with rhBMP-7 resulted in the development of a chimeric bone organ including a large number of human mesenchymal cells which were shown to be metabolically active and capable of establishing a humanized microenvironment supportive of the homing and maintenance of human HSCs. A syngeneic mouse-to-mouse transplantation assay was used to prove the functionality of the tissue-engineered ossicles. We predict that the ability to tissue engineer a morphologically intact and functional large-volume bone organ with a humanized bone marrow compartment will help to further elucidate physiological or pathological interactions between human HSCs and their native niches. Crown Copyright © 2015. Published by Elsevier Ltd. All rights reserved.

  20. TEPCO's Approach to Power-Engineer Human Resource Development

    Science.gov (United States)

    Sato, Masaki

    We think 'human resources and technology' is developed only by self-training continuously, keeping higher motivation and practicing repeatedly. Moreover it is indispensable for sustainable development of company. Management vision, top-down message with vertical communication, and bottom-up systematic approaches are necessary for sustainable human resource development, sharing the value with coordination, and in addition, OJT and Off-JT method should be used effectively. This paper shows TEPCO's attempts to develop engineers' technical skills as a reference of a in-company continuing professional development.

  1. Tissue-engineered models of human tumors for cancer research

    Science.gov (United States)

    Villasante, Aranzazu; Vunjak-Novakovic, Gordana

    2015-01-01

    Introduction Drug toxicity often goes undetected until clinical trials, which are the most costly and dangerous phase of drug development. Both the cultures of human cells and animal studies have limitations that cannot be overcome by incremental improvements in drug-testing protocols. A new generation of bioengineered tumors is now emerging in response to these limitations, with potential to transform drug screening by providing predictive models of tumors within their tissue context, for studies of drug safety and efficacy. An area that could greatly benefit from these models is cancer research. Areas covered In this review, the authors first describe the engineered tumor systems, using Ewing's sarcoma as an example of human tumor that cannot be predictably studied in cell culture and animal models. Then, they discuss the importance of the tissue context for cancer progression and outline the biomimetic principles for engineering human tumors. Finally, they discuss the utility of bioengineered tumor models for cancer research and address the challenges in modeling human tumors for use in drug discovery and testing. Expert opinion While tissue models are just emerging as a new tool for cancer drug discovery, they are already demonstrating potential for recapitulating, in vitro, the native behavior of human tumors. Still, numerous challenges need to be addressed before we can have platforms with a predictive power appropriate for the pharmaceutical industry. Some of the key needs include the incorporation of the vascular compartment, immune system components, and mechanical signals that regulate tumor development and function. PMID:25662589

  2. Accreditation of Engineering Programs: An Evaluation of Current Practices in Malaysia

    Science.gov (United States)

    Said, Suhana Mohd; Chow, Chee-Onn; Mokhtar, N.; Ramli, Rahizar; Ya, Tuan Mohd Yusoff Shah Tuan; Sabri, Mohd Faizul Mohd

    2013-01-01

    The curriculum for undergraduate engineering courses in Malaysia is becoming increasingly structured, following the global trend for quality assurance in engineering education, through accreditation schemes. Generally, the accreditation criteria call for the graduates from engineering programs to demonstrate a range of skills, from technical…

  3. Environmental Field Surveys, EMF Rapid Program, Engineering Project No.3

    Energy Technology Data Exchange (ETDEWEB)

    Enertech Consultants

    1996-04-01

    The EMF Research and Public Information Dissemination Program (RAPID) includes several engineering research in the area of exposure assessment and source characterization. RAPID engineering project No. 3: ''Environmental Field Surveys'' was performed to obtain information on the levels and characteristics of different environments, for which only limited data were available, especially in comparison to magnetic field data for the residential environment and for electric utility facilities, such as power lines and substations. This project was also to provide information on the contribution of various field sources in the surveyed environments. Magnetic field surveys were performed at four sites for each of five environments: schools, hospitals, office buildings, machine shops, and grocery stores. Of the twenty sites surveyed, 11 were located in the San Francisco Bay Area and 9 in Massachusetts. The surveys used a protocol based on magnetic field measurements and observation of activity patterns, designed to provide estimates of magnetic field exposure by type of people and by type of sources. The magnetic field surveys conducted by this project produced a large amount of data which will form a part of the EMF measurement database Field and exposure data were obtained separately for ''area exposure'' and ''at exposure points''. An exposure point is a location where persons engage in fixed, site specific activities near a local source that creates a significant increase in the area field. The area field is produced by ''area sources'', whose location and field distribution is in general not related to the location of the people in the area.

  4. Young engineers and scientists - a mentorship program emphasizing space education

    Science.gov (United States)

    Boice, Daniel; Asbell, Elaine; Reiff, Patricia

    Young Engineers and Scientists (YES) is a community partnership between Southwest Research Institute (SwRI), and local high schools in San Antonio, Texas (USA) during the past 16 years. The YES program provides talented high school juniors and seniors a bridge between classroom instruction and real world, research experiences in physical sciences (including space science) and engineering. The first component of YES is an intensive three-week summer workshop held at SwRI where students experience the research environment first-hand; develop skills and acquire tools for solving scientific problems, attend mini-courses and seminars on electronics, computers and the Internet, careers, science ethics, and other topics; and select individual research projects to be completed during the academic year. Afterwards, students complete individual research projects under the guidance of their mentors during the academic year and earn honors credit. At the end of the school year, students publicly present and display their work, acknowledging their accomplishments and spreading career awareness to other students and teachers. During these years, YES has developed a website for topics in space science from the perspective of high school students, including NASA's Magnetospheric Multiscale Mission (MMS) (http://yesserver.space.swri.edu). High school science teachers participate in the workshop and develop space-related lessons for classroom presentation in the academic year. Student evaluations indicate the effectiveness of YES on their academic preparation and choice of college majors. Over the past 16 years, all YES graduates have entered college, several have worked for SwRI, one business has started, and three scientific publications have resulted. Acknowledgements. We acknowledge funding and support from the NASA MMS Mission, Texas Space Grant Consortium, Northside Independent School District, SwRI, and several local charitable foundations.

  5. Prenatal programming of human neurological function.

    Science.gov (United States)

    Sandman, Curt A; Davis, Elysia P; Buss, Claudia; Glynn, Laura M

    2011-01-01

    The human placenta expresses the genes for proopiomelanocortin and the major stress hormone, corticotropin-releasing hormone (CRH), profoundly altering the "fight or flight" stress system in mother and fetus. As pregnancy progresses, the levels of these stress hormones, including maternal cortisol, increase dramatically. These endocrine changes are important for fetal maturation, but if the levels are altered (e.g., in response to stress), they influence (program) the fetal nervous system with long-term consequences. The evidence indicates that fetal exposure to elevated levels of stress hormones (i) delays fetal nervous system maturation, (ii) restricts the neuromuscular development and alters the stress response of the neonate, (iii) impairs mental development and increases fearful behavior in the infant, and (iv) may result in diminished gray matter volume in children. The studies reviewed indicate that fetal exposure to stress peptides and hormones exerts profound programming influences on the nervous system and may increase the risk for emotional and cognitive impairment.

  6. Survey of Forest Engineering and Forest Operations Programs in North America

    OpenAIRE

    Dodson, Elisabeth M; Bolding, Chad; Spong, Ben

    2010-01-01

    In 1999 the International Journal of Forest Engineering published a special edition titled “Forest Engineering – Looking Ahead Ten Years.” The lead article was “Graduate programs in forest engineering and forest operations: working towards extinction.” McNeel, Stokes, and Brinker surveyed graduate programs in North America that have named graduate programs in forest engineering and forest operations (FE/FO) with a primary focus on PhD‐level graduates. Concerns were raised over the low numbers...

  7. The 1993 NASA-ODU American Society for Engineering Education (ASEE) Summer Faculty Fellowship Program

    Science.gov (United States)

    Tiwari, Surendra N. (Compiler); Young, Deborah B. (Compiler)

    1993-01-01

    Since 1964, the National Aeronautics and Space Administration has supported a program of summer faculty fellowships for engineering and science educators. In a series of collaborations between NASA research and development centers and nearby universities, engineering faculty members spend 10 weeks working with professional peers on research. The Summer Faculty Program Committee of the American Society for Engineering Education supervises the programs. Objectives are: to further the professional knowledge of qualified engineering and science faculty members; to stimulate and exchange ideas between participants and NASA; to enrich and refresh the research and teaching activities of participants' institutions; and to contribute to the research objectives of the NASA center.

  8. 1994 NASA-HU American Society for Engineering Education (ASEE) Summer Faculty Fellowship Program

    Science.gov (United States)

    Spencer, John H. (Compiler); Young, Deborah B. (Compiler)

    1994-01-01

    Since 1964, the National Aeronautics and Space Administration (NASA) has supported a program of summer faculty fellowships for engineering and science educators. In a series of collaborations between NASA research and development centers and nearby universities, engineering faculty members spend 10 weeks working with professional peers on research. The Summer Faculty Program Committee of the American Society for Engineering Education supervises the programs. Objectives: (1) To further the professional knowledge of qualified engineering and science faculty members; (2) To stimulate and exchange ideas between participants and NASA; (3) To enrich and refresh the research and teaching activities of participants' institutions; (4) To contribute to the research objectives of the NASA center.

  9. Bachelor of Science-Engineering Technology Program and Fuel Cell Education Program Concentration

    Energy Technology Data Exchange (ETDEWEB)

    Block, David L. [Florida Solar Energy Center, Cocoa, FL (United States); Sleiti, Ahmad [Univ. of North Carolina, Charlotte, NC (United States)

    2011-09-19

    The Hydrogen and Fuel Cell Technology education project has addressed DOE goals by supplying readily available, objective, technical, and accurate information that is available to students, industry and the public. In addition, the program has supplied educated trainers and training opportunities for the next generation workforce needed for research, development, and demonstration activities in government, industry, and academia. The project has successfully developed courses and associated laboratories, taught the new courses and labs and integrated the HFCT option into the accredited engineering technology and mechanical engineering programs at the University of North Carolina at Charlotte (UNCC). The project has also established ongoing collaborations with the UNCC energy related centers of the Energy Production & Infrastructure Center (EPIC), the NC Motorsports and Automotive Research Center (NCMARC) and the Infrastructure, Design, Environment and Sustainability Center (IDEAS). The results of the project activities are presented as two major areas – (1) course and laboratory development, offerings and delivery, and (2) program recruitment, promotions and collaborations. Over the project period, the primary activity has been the development and offering of 11 HFCT courses and accompanying laboratories. This process has taken three years with the courses first being developed and then offered each year over the timeframe.

  10. Evaluation of the 1997 Joint National Conference, Women in Engineering Program Advocates Network (WEPAN) and National Association of Minority Engineering Program Administrators (NAMEPA)

    Energy Technology Data Exchange (ETDEWEB)

    Brainard, Suzanne G.

    1997-07-01

    The primary goal of the 1997 Joint National Conference was to unite NAMEPA and WEPAN in a unique collaborative effort to further the cause of increasing the participation of women and minorities in science and engineering. The specific objectives were to: (1) conduct technical and programmatic seminars for institutions desiring to initiate, replicate, or expand women and minorities in engineering program; (2) provide assistance in fundraising and grant writing; (3) profile women in engineering programs of excellence; (4) sponsor inspiring knowledgeable and motivational keynote speakers; and (5) offer a series of workshops focused on a multitude of topics.

  11. The Value of Graduate Certificate Programs in Engineering Education: A Strategic Assessment

    Science.gov (United States)

    Murray, Susan L.; Long, Suzanna K.; Elrod, Cassandra C.; Akula, Susmitha

    2011-01-01

    There has been a significant increase in the popularity of non-degree graduate certificates throughout the past decade. This increase has raised questions about the value of engineering graduate certificate programs from students, alumni, and employers. Do engineering certificate programs provide real world skills and knowledge? Do they serve as…

  12. The Implementation and Evaluation of a University-Based Outreach Laboratory Program in Electrical Engineering

    Science.gov (United States)

    Smaill, Chris R.

    2010-01-01

    In the current climate of shortages of high-quality engineering graduates, exacerbated by reduced high school enrollments in physics and mathematics, engineering faculties are becoming increasingly aware of the importance of K-12 outreach programs. Such programs can result in students being better prepared for and better informed about engineering…

  13. Human factors engineering checklists for application in the SAR process

    Energy Technology Data Exchange (ETDEWEB)

    Overlin, T.K.; Romero, H.A.; Ryan, T.G.

    1995-03-01

    This technical report was produced to assist the preparers and reviewers of the human factors portions of the SAR in completing their assigned tasks regarding analysis and/or review of completed analyses. The checklists, which are the main body of the report, and the subsequent tables, were developed to assist analysts in generating the needed analysis data to complete the human engineering analysis for the SAR. The technical report provides a series of 19 human factors engineering (HFE) checklists which support the safety analyses of the US Department of Energy`s (DOE) reactor and nonreactor facilities and activities. The results generated using these checklists and in the preparation of the concluding analyses provide the technical basis for preparing the human factors chapter, and subsequent inputs to other chapters, required by DOE as a part of the safety analysis reports (SARs). This document is divided into four main sections. The first part explains the origin of the checklists, the sources utilized, and other information pertaining to the purpose and scope of the report. The second part, subdivided into 19 sections, is the checklists themselves. The third section is the glossary which defines terms that could either be unfamiliar or have specific meanings within the context of these checklists. The final section is the subject index in which the glossary terms are referenced back to the specific checklist and page the term is encountered.

  14. Engineering antigen-specific T cells from genetically modified human hematopoietic stem cells in immunodeficient mice.

    Directory of Open Access Journals (Sweden)

    Scott G Kitchen

    Full Text Available There is a desperate need for effective therapies to fight chronic viral infections. The immune response is normally fastidious at controlling the majority of viral infections and a therapeutic strategy aimed at reestablishing immune control represents a potentially powerful approach towards treating persistent viral infections. We examined the potential of genetically programming human hematopoietic stem cells to generate mature CD8+ cytotoxic T lymphocytes that express a molecularly cloned, "transgenic" human anti-HIV T cell receptor (TCR. Anti-HIV TCR transduction of human hematopoietic stem cells directed the maturation of a large population of polyfunctional, HIV-specific CD8+ cells capable of recognizing and killing viral antigen-presenting cells. Thus, through this proof-of-concept we propose that genetic engineering of human hematopoietic stem cells will allow the tailoring of effector T cell responses to fight HIV infection or other diseases that are characterized by the loss of immune control.

  15. Final report for the Gateway to Engineering, Science and Technology (GEST) program

    Energy Technology Data Exchange (ETDEWEB)

    Miller, M.

    1998-04-01

    This report describes the performance of a two year grant to provide partial funding for an engineering/science/mathematics program at the University of Wisconsin, Milwaukee. This program serves middle and high school students in a summer program coupled with academic year activities, and is designed to attract underrepresented students into these disciplines. The UWM program has been running since 1974.

  16. Mechanical stimulation improves tissue-engineered human skeletal muscle

    Science.gov (United States)

    Powell, Courtney A.; Smiley, Beth L.; Mills, John; Vandenburgh, Herman H.

    2002-01-01

    Human bioartificial muscles (HBAMs) are tissue engineered by suspending muscle cells in collagen/MATRIGEL, casting in a silicone mold containing end attachment sites, and allowing the cells to differentiate for 8 to 16 days. The resulting HBAMs are representative of skeletal muscle in that they contain parallel arrays of postmitotic myofibers; however, they differ in many other morphological characteristics. To engineer improved HBAMs, i.e., more in vivo-like, we developed Mechanical Cell Stimulator (MCS) hardware to apply in vivo-like forces directly to the engineered tissue. A sensitive force transducer attached to the HBAM measured real-time, internally generated, as well as externally applied, forces. The muscle cells generated increasing internal forces during formation which were inhibitable with a cytoskeleton depolymerizer. Repetitive stretch/relaxation for 8 days increased the HBAM elasticity two- to threefold, mean myofiber diameter 12%, and myofiber area percent 40%. This system allows engineering of improved skeletal muscle analogs as well as a nondestructive method to determine passive force and viscoelastic properties of the resulting tissue.

  17. Mechanical stimulation improves tissue-engineered human skeletal muscle

    Science.gov (United States)

    Powell, Courtney A.; Smiley, Beth L.; Mills, John; Vandenburgh, Herman H.

    2002-01-01

    Human bioartificial muscles (HBAMs) are tissue engineered by suspending muscle cells in collagen/MATRIGEL, casting in a silicone mold containing end attachment sites, and allowing the cells to differentiate for 8 to 16 days. The resulting HBAMs are representative of skeletal muscle in that they contain parallel arrays of postmitotic myofibers; however, they differ in many other morphological characteristics. To engineer improved HBAMs, i.e., more in vivo-like, we developed Mechanical Cell Stimulator (MCS) hardware to apply in vivo-like forces directly to the engineered tissue. A sensitive force transducer attached to the HBAM measured real-time, internally generated, as well as externally applied, forces. The muscle cells generated increasing internal forces during formation which were inhibitable with a cytoskeleton depolymerizer. Repetitive stretch/relaxation for 8 days increased the HBAM elasticity two- to threefold, mean myofiber diameter 12%, and myofiber area percent 40%. This system allows engineering of improved skeletal muscle analogs as well as a nondestructive method to determine passive force and viscoelastic properties of the resulting tissue.

  18. Engineering melanoma progression in a humanized environment in vivo.

    Science.gov (United States)

    Kiowski, Gregor; Biedermann, Thomas; Widmer, Daniel S; Civenni, Gianluca; Burger, Charlotte; Dummer, Reinhard; Sommer, Lukas; Reichmann, Ernst

    2012-01-01

    To overcome the lack of effective therapeutics for aggressive melanoma, new research models closely resembling the human disease are required. Here we report the development of a fully orthotopic, humanized in vivo model for melanoma, faithfully recapitulating human disease initiation and progression. To this end, human melanoma cells were seeded into engineered human dermo-epidermal skin substitutes. Transplantation onto the back of immunocompromised rats consistently resulted in the development of melanoma, displaying the hallmarks of their parental tumors. Importantly, all initial steps of disease progression were recapitulated, including the incorporation of the tumor cells into their physiological microenvironment, transition of radial to vertical growth, and establishment of highly vascularized, aggressive tumors with dermal involvement. Because all cellular components can be individually accessed using this approach, it allows manipulation of the tumor cells, as well as of the keratinocyte and stromal cell populations. Therefore, in one defined model system, tumor cell-autonomous and non-autonomous pathways regulating human disease progression can be investigated in a humanized, clinically relevant context.

  19. Automotive Stirling Engine Development Program. RESD summary report

    Science.gov (United States)

    1984-01-01

    The design of reference Stirling engine system as well as the engine auxiliaries and controls is described. Manufacturing costs in production quantity are also presented. Engine system performance predictions are discussed and vehicle integration is developed, along with projected fuel economy levels.

  20. The ACCEND program: a combined BS and MS program in environmental engineering that includes co-operative work experience.

    Science.gov (United States)

    Bishop, P L; Keener, T C; Kukreti, A R; Kowel, S T

    2004-01-01

    Environmental engineering education has rapidly expanded in recent years and new teaching methods are needed. Many professionals and educators believe that a MS degree in environmental engineering should be the minimum in order to practice the profession, along with practical training. This paper describes an innovative program being offered at the University of Cincinnati that combines an integrated BS in civil engineering and an MS in environmental engineering with extensive practical co-operative education (co-op) experience, all within a five-year period. The program includes distance learning opportunities during the co-op periods. The result is a well-trained graduate who will receive higher pay and more challenging career opportunities, and who will have developed professionalism and maturity beyond that from traditional engineering programs.

  1. Maturing human pluripotent stem cell-derived cardiomyocytes in human engineered cardiac tissues.

    Science.gov (United States)

    Feric, Nicole T; Radisic, Milica

    2016-01-15

    Engineering functional human cardiac tissue that mimics the native adult morphological and functional phenotype has been a long held objective. In the last 5 years, the field of cardiac tissue engineering has transitioned from cardiac tissues derived from various animal species to the production of the first generation of human engineered cardiac tissues (hECTs), due to recent advances in human stem cell biology. Despite this progress, the hECTs generated to date remain immature relative to the native adult myocardium. In this review, we focus on the maturation challenge in the context of hECTs, the present state of the art, and future perspectives in terms of regenerative medicine, drug discovery, preclinical safety testing and pathophysiological studies. Copyright © 2015 Elsevier B.V. All rights reserved.

  2. National education program for energy efficient illumination engineering

    Science.gov (United States)

    Walker, Constance E.; Pompea, Stephen M.

    2011-05-01

    About one-third of outdoor lighting escapes unused into the sky, wasting energy and causing sky glow. Because of excessive sky glow around astronomical facilities, the National Optical Astronomy Observatory has a strong motivation to lead light pollution education efforts. While our original motivation of preserving the dark skies near observatories is still important, energy conservation is a critical problem that needs to be addressed nationwide. To address this problem we have created an extensive educational program on understanding and measuring light pollution. A set of four learning experiences introduces school students at all grade levels to basic energy-responsive illumination engineering design principles that can minimize light pollution. We created and utilize the GLOBE at Night citizen science light pollution assessment campaign as a cornerstone activity. We also utilize educational activities on light shielding that are introduced through a teaching kit. These two components provide vocabulary, concepts, and visual illustrations of the causes of light pollution. The third, more advanced component is the school outdoor lighting audit, which has students perform an audit and produce a revised master plan for compliant lighting. These learning experiences provide an integrated learning unit that is highly adaptable for U.S. and international education efforts in this area.

  3. [Mapping and human genome sequence program].

    Science.gov (United States)

    Weissenbach, J

    1997-03-01

    Until recently, human genome programs focused primarily on establishing maps that would provide signposts to researchers seeking to identify genes responsible for inherited diseases, as well as a basis for genome sequencing studies. Preestablished gene mapping goals have been reached. The over 7,000 microsatellite markers identified to date provide a map of sufficient density to allow localization of the gene of a monogenic disease with a precision of 1 to 2 million base pairs. The physical map, based on systematically arranged overlapping sets of artificial yeast chromosomes (YACs), has also made considerable headway during the last few years. The most recently published map covers more than 90% of the genome. However, currently available physical maps cannot be used for sequencing studies because multiple rearrangements occur in YACs. The recently developed sets of radioinduced hybrids are extremely useful for incorporating genes into existing maps. A network of American and European laboratories has successfully used these radioinduced hybrids to map 15,000 gene tags from large-scale cDNA library sequencing programs. There are increasingly pressing reasons for initiating large scale human genome sequencing studies.

  4. Understanding the Front-end of Large-scale Engineering Programs

    DEFF Research Database (Denmark)

    Lucae, Sebastian; Rebentisch, Eric; Oehmen, Josef

    2014-01-01

    from large cost overruns. Significant problems in program execution can be traced back to practices performed, or more frequently not performed, in the so-called “fuzzy front end” of the program. The lack of sufficient and effective efforts in the early stages of a program can result in unstable......, to propose a model for the front-end of large-scale engineering programs based on a review of existing, suitable models in literature and to better understand the complexity drivers that are impeding reliable planning and common planning mistakes made in large-scale engineering programs......., unclear and incomplete requirements, unclear roles and responsibilities within the program organization, insufficient planning, and unproductive tensions between program management and systems engineering. This study intends to clarify the importance of up-front planning to improve program performance...

  5. Predictors Of Java Programming Self Efficacy Among Engineering Students In A Nigerian University

    CERN Document Server

    Jegede, Philip Olu

    2009-01-01

    The study examined the relationship between Java programming self-efficacy and programming background of engineering students in a Nigerian University. One hundred and ninety two final year engineering students randomly selected from six engineering departments of the university participated in the study. Two research instruments: Programming Background Questionnaire and Java Programming Self-Efficacy Scale were used in collecting relevant information from the subjects. The resulting data were analyzed using Pearson product correlation and Multiple regression analysis. Findings revealed that Java Programming self-efficacy has no significant relationship with each of the computing and programming background factors. It was additionally obtained that the number of programming courses offered and programming courses weighed scores were the only predictors of Java self-efficacy.

  6. An Educational Program for Newcomers to Enhance their Engineering Motivation and Creativity in Faculty of Engineering at Shizuoka University

    Science.gov (United States)

    Azuma, Naoto; Fujima, Nobuhisa; Nakamura, Tamotsu; Yamada, Shinkichi; Makizawa, Hisamitsu; Nakamura, Takato

    In Faculty of Engineering at Shizuoka University, a new one-year educational program of mechatronics for newcomers will start at April in 2006. This program involves three stages designed to enhance their motivation and creativity in engineering. At the first and second stages, there are three activities; practicing digital circuits, controlling robots with Boe-Bot from Parallax Inc., and making their own microcontroller boards. At the third stage, each student cooperates with his team-mates to make a robot loaded his own board and through the game-type of competition the performance of each team-robot is scored. Through this program, we hope that our students enhance their engineering motivation and creativity.

  7. Participant outcomes, perceptions, and experiences in the Internationally Educated Engineers Qualification Program, University of Manitoba: An exploratory study

    Science.gov (United States)

    Friesen, Marcia R.

    Immigration, economic, and regulatory trends in Canada have challenged all professions to examine the processes by which immigrant professionals (international graduates) achieve professional licensure and meaningful employment in Canada. The Internationally Educated Engineers Qualification Program (IEEQ) at the University of Manitoba was developed as an alternate pathway to integrate international engineering graduates into the engineering profession in Manitoba. However, universities have the neither mandate nor the historical practice to facilitate licensure for immigrant professionals and, thus, the knowledge base for program development and delivery is predominantly experiential. This study was developed to address the void in the knowledge base and support the program's ongoing development by conducting a critical, exploratory, participant-oriented evaluation of the IEEQ Program for both formative and summative purposes. The research questions focussed on how the IEEQ participants perceived and described their experiences in the IEEQ Program, and how the participants' outcomes in the IEEQ Program compared to international engineering graduates pursuing other licensing pathways. The study was built on an interpretivist theoretical approach that supported a primarily qualitative methodology with selected quantitative elements. Data collection was grounded in focus group interviews, written questionnaires, student reports, and program records for data collection, with inductive data analysis for qualitative data and descriptive statistics for quantitative data. The findings yielded rich understandings of participants' experiences in the IEEQ Program, their outcomes relative to international engineering graduates (IEGs) pursuing other licensing pathways, and their perceptions of their own adaptation to the Canadian engineering profession. Specifically, the study suggests that foreign credentials recognition processes have tended to focus on the recognition and

  8. Method for Incorporation of Controllability in Heat Exchanger Network Synthesis by Integrating Mathematical Programming and Knowledge Engineering

    Institute of Scientific and Technical Information of China (English)

    李志红

    2002-01-01

    A method for incorporation of controlling the heat exchanger networks with or without splits is proposed by integrating mathematical programming and knowledge engineering.The simultaneous optimal mathematical model is established.This method can be practically used in the integration of large-scale heat exchanger networks,not only to synthesize automatically but also to satisfy the requirement of structural controllability with more nobjective human intervention.

  9. `Human nature': Chemical engineering students' ideas about human relationships with the natural world

    Science.gov (United States)

    Goldman, Daphne; Ben-Zvi Assaraf, Orit; Shemesh, Julia

    2014-05-01

    While importance of environmental ethics, as a component of sustainable development, in preparing engineers is widely acknowledged, little research has addressed chemical engineers' environmental concerns. This study aimed to address this void by exploring chemical engineering students' values regarding human-nature relationships. The study was conducted with 247 3rd-4th year chemical engineering students in Israeli Universities. It employed the New Ecological Paradigm (NEP)-questionnaire to which students added written explanations. Quantitative analysis of NEP-scale results shows that the students demonstrated moderately ecocentric orientation. Explanations to the NEP-items reveal diverse, ambivalent ideas regarding the notions embodied in the NEP, strong scientific orientation and reliance on technology for addressing environmental challenges. Endorsing sustainability implies that today's engineers be equipped with an ecological perspective. The capacity of Higher Education to enable engineers to develop dispositions about human-nature interrelationships requires adaptation of curricula towards multidisciplinary, integrative learning addressing social-political-economic-ethical perspectives, and implementing critical-thinking within the socio-scientific issues pedagogical approach.

  10. Educational Challenges for Engineering. Keynote Address, Engineering in the Service of Society: New Educational Programs. IEEE Workshop Record (University of Kentucky, Lexington, August 26-27, 1974).

    Science.gov (United States)

    Truxal, John G.

    Cited are the educational challenges of undergraduate, graduate, and professional engineering programs; the main emphasis is on the challente to provide engineering education for non-engineering students at both the undergraduate and adult levels. The need for such a program stems from a conviction that no citizen can be considered educated in…

  11. 1997 LMITCO Environmental Monitoring Program Report for the Idaho National Engineering and Environmental Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Andersen, B.; Street, L.; Wilhelmsen, R.

    1998-09-01

    This report describes the calendar year 1997 environmental surveillance and compliance monitoring activities of the Lockheed Martin Idaho Technologies Company Environmental Monitoring Program performed at the Idaho National Engineering and Environmental Laboratory. This report includes results of sampling performed by the Radiological Environmental Surveillance, Site Environmental Surveillance, Drinking Water, Effluent Monitoring, Storm Water Monitoring, Groundwater Monitoring, and Special Request Monitoring Programs and compares 1997 data with program-specific regulatory guidelines and past data to evaluate trends. The primary purposes of the surveillance and monitoring activities are to evaluate environmental conditions, to provide and interpret data, to verify compliance with applicable regulations or standard, and to ensure protection of human health and the environment. Surveillance of environmental media did not identify any previously unknown environmental problems or trends indicating a loss of control or unplanned releases from facility operations. With the exception of one nitrogen sample in the disposal pond effluent stream and iron and total coliform bacteria in groundwater downgradient from one disposal pond, compliance with permits and applicable regulations was achieved. Data collected by the Environmental Monitoring Program demonstrate that public health and the environment were protected.

  12. The GEORED and Plate Boundary Observatory Engineer Exchange Program

    Science.gov (United States)

    Feaux, K.; Mora-Paez, H.

    2007-05-01

    In early 2007, the Colombian Institute of Geology and Mining - INGEOMINAS initiated GEORED (Geodesia: Red de Estudios de Deformación) in order to increase the knowledge of the geodynamics of northwestern South America. GEORED is an essential tool for determining crustal deformation and is primary in the analysis of inter- plate and intraplate deformation and the present seismic cycle. Some of the objectives of the project are to improve the technical, scientific, and operational capabilities of Colombian scientists regarding tectonic and volcanic deformation in Colombia, to implement a Colombian GPS permanent network for the study of geodynamics, with near real-time data retrieval and processing, and to establish a high precision geodetic reference frame for multipurpose activities within INGEOMINAS. Phase 1 of GEORED, which includes the installation of 30 permanent GPS stations in Colombia, will commence in early 2007. The Plate Boundary Observatory (PBO), part of the larger NSF-funded EarthScope project managed by UNAVCO, will study the three-dimensional strain field resulting from active plate boundary deformation across the Western United States. PBO is a large construction project involving the reconnaissance, permitting, installation, documentation, and maintenance of 875 permanent GPS stations scheduled for completion in September 2008. PBO is currently in the fourth year of the project, with over 550 GPS stations completed to date. INGEOMINAS recently became a member of the UNAVCO consortium. UNAVCO has been working with INGEOMINAS by providing technical support for the GEORED project relating to GPS receiver specifications. In the spirit of collaboration and outreach, INGEOMINAS and UNAVCO will begin an engineer exchange program starting in early summer 2007. The purpose of this outreach program is to provide a mechanism for the exchange of ideas relating to GPS station construction techniques, hardware designs, data communications, and data archiving

  13. Human Factors Engineering (HFE) insights for advanced reactors based upon operating experience

    Energy Technology Data Exchange (ETDEWEB)

    Higgins, J.; Nasta, K.

    1997-01-01

    The NRC Human Factors Engineering Program Review Model (HFE PRM, NUREG-0711) was developed to support a design process review for advanced reactor design certification under 10CFR52. The HFE PRM defines ten fundamental elements of a human factors engineering program. An Operating Experience Review (OER) is one of these elements. The main purpose of an OER is to identify potential safety issues from operating plant experience and ensure that they are addressed in a new design. Broad-based experience reviews have typically been performed in the past by reactor designers. For the HFE PRM the intent is to have a more focussed OER that concentrates on HFE issues or experience that would be relevant to the human-system interface (HSI) design process for new advanced reactors. This document provides a detailed list of HFE-relevant operating experience pertinent to the HSI design process for advanced nuclear power plants. This document is intended to be used by NRC reviewers as part of the HFE PRM review process in determining the completeness of an OER performed by an applicant for advanced reactor design certification. 49 refs.

  14. Human resources in science and engineering: Policy implications

    Energy Technology Data Exchange (ETDEWEB)

    Leggon, C.B.

    1995-12-31

    Recently, there has been much debate concerning the adequacy of the United States` (U.S.) human resources base to meet its future needs for science and engineering (S/E) talent. Science policy analysts - and scientists and engineers themselves - disagree about whether there will be any shortages of scientists and engineers, and if so, what they will mean for the U.S. Whether or not these shortages materialize, it is necessary for the U.S. to expand the pool from which it recruits its S/E talent. This paper addresses the question of how to increases the diversity of the S/E talent pool to include those who are projected by the year 2000 to be the majority of entry-level workers in the U.S. workforce: women and racial/ethnic minorities. Market forces alone cannot increase the size and diversity of the U.S. S/E workforce. Policy intervention will continue to be required to increase the diversity of the S/E workforce.

  15. 78 FR 56132 - Human Reliability Program: Technical Amendments

    Science.gov (United States)

    2013-09-12

    ... Part 712 RIN 1992-AA44 Human Reliability Program: Technical Amendments AGENCY: Department of Energy... Reliability Program (HRP) regulations to eliminate references to obsolete provisions and to update part 712 to... III, title 10, Code of Federal Regulations, as set forth below: PART 712--HUMAN RELIABILITY PROGRAM...

  16. Advancing biomaterials of human origin for tissue engineering.

    Science.gov (United States)

    Chen, Fa-Ming; Liu, Xiaohua

    2016-02-01

    Biomaterials have played an increasingly prominent role in the success of biomedical devices and in the development of tissue engineering, which seeks to unlock the regenerative potential innate to human tissues/organs in a state of deterioration and to restore or reestablish normal bodily function. Advances in our understanding of regenerative biomaterials and their roles in new tissue formation can potentially open a new frontier in the fast-growing field of regenerative medicine. Taking inspiration from the role and multi-component construction of native extracellular matrices (ECMs) for cell accommodation, the synthetic biomaterials produced today routinely incorporate biologically active components to define an artificial in vivo milieu with complex and dynamic interactions that foster and regulate stem cells, similar to the events occurring in a natural cellular microenvironment. The range and degree of biomaterial sophistication have also dramatically increased as more knowledge has accumulated through materials science, matrix biology and tissue engineering. However, achieving clinical translation and commercial success requires regenerative biomaterials to be not only efficacious and safe but also cost-effective and convenient for use and production. Utilizing biomaterials of human origin as building blocks for therapeutic purposes has provided a facilitated approach that closely mimics the critical aspects of natural tissue with regard to its physical and chemical properties for the orchestration of wound healing and tissue regeneration. In addition to directly using tissue transfers and transplants for repair, new applications of human-derived biomaterials are now focusing on the use of naturally occurring biomacromolecules, decellularized ECM scaffolds and autologous preparations rich in growth factors/non-expanded stem cells to either target acceleration/magnification of the body's own repair capacity or use nature's paradigms to create new tissues for

  17. Characterization of human myoblast cultures for tissue engineering.

    Science.gov (United States)

    Stern-Straeter, Jens; Bran, Gregor; Riedel, Frank; Sauter, Alexander; Hörmann, Karl; Goessler, Ulrich Reinhart

    2008-01-01

    Skeletal muscle tissue engineering, a promising specialty, aims at the reconstruction of skeletal muscle loss. In vitro tissue engineering attempts to achieve this goal by creating differentiated, functional muscle tissue through a process in which stem cells are extracted from the patient, e.g. by muscle biopsies, expanded and differentiated in a controlled environment, and subsequently re-implanted. A prerequisite for this undertaking is the ability to cultivate and differentiate human skeletal muscle cell cultures. Evidently, optimal culture conditions must be investigated for later clinical utilization. We therefore analysed the proliferation of human cells in different environments and evaluated the differentiation potential of different culture media. It was shown that human myoblasts have a higher rate of proliferation in the alamarBlue assay when cultured on gelatin-coated culture flasks rather than polystyrene-coated flasks. We also demonstrated that myoblasts treated with a culture medium with a high concentration of growth factors [growth medium (GM)] showed a higher proliferation compared to cultures treated with a culture medium with lower amounts of growth factors [differentiation medium (DM)]. Differentiation of human myoblast cell cultures treated with GM and DM was analysed until day 16 and myogenesis was verified by expression of MyoD, myogenin, alpha-sarcomeric actin and myosin heavy chain by semi-quantitative RT-PCR. Immunohistochemical staining for desmin, Myf-5 and alpha-sarcomeric actin was performed to verify the myogenic phenotype of extracted satellite cells and to prove the maturation of cells. Cultures treated with DM showed positive staining for alpha-sarcomeric actin. Notably, markers of differentiation were also detected in cultures treated with GM, but there was no formation of myotubes. In the enzymatic assay of creatine phosphokinase, cultures treated with DM showed a higher activity, evidencing a higher degree of differentiation

  18. Software Engineering Education at Carnegie Mellon University: One University; Programs Taught in Two Places

    Directory of Open Access Journals (Sweden)

    Mel Rosso-Llopart

    2009-10-01

    Full Text Available Teaching Software Engineering to professional master‟s students is a challenging endeavor, and arguably for the past 20 years, Carnegie Mellon University has been quite successful. Although CMU teaches Software Engineering at sites world-wide and uses different pedagogies, the goal of the curriculum -- to produce world-class software engineers -- remains constant. This paper will discuss two of the most mature versions of Carnegie Mellon‟s Software Engineering program -- the main campus program and its "daughter program" at the Silicon Valley Campus. We discuss the programs with respect to the dimensions of curriculum, how students work and learn, how faculty teach, curricular materials, and how students are assessed to provide insight into how Carnegie Mellon continues to keep its programs fresh, to adapt them to local needs, and to meet its goal of excellence after 20 years.

  19. 76 FR 12271 - Human Reliability Program: Identification of Reviewing Official

    Science.gov (United States)

    2011-03-07

    ... Part 712 RIN 1992-AZ00 Human Reliability Program: Identification of Reviewing Official AGENCY: Department of Energy (DOE). ACTION: Final rule. SUMMARY: DOE is amending the Human Reliability Program (HRP... damage national security. To guard against such compromise, DOE established the Human Reliability...

  20. The JT8D and JT9D engine component improvement: Performance improvement program

    Science.gov (United States)

    Gaffin, W. O.

    1982-01-01

    The NASA sponsored Engine Component Improvement - Performance Improvement Program at Pratt & Whitney Aircraft advanced the state of the art of thermal barrier coatings and ceramic seal systems, demonstrated the practicality of an advanced turbine clearance control system and an advanced fan design in the JT9D engine, and demonstrated the advantages of modern cooling, sealing, and aerodynamic designs in the high pressure turbine and compressor of the JT8D engine. Several of these improvements are already in airline service in JT8D and JT9D engines, and others will enter service soon in advanced models of these engines. In addition, the technology advances are being transferred to completely new engine configurations, the PW2037 engine and the NASA sponsored Energy Efficient Engine.

  1. Prenatal Programming of Human Neurological Function

    Directory of Open Access Journals (Sweden)

    Curt A. Sandman

    2011-01-01

    Full Text Available The human placenta expresses the genes for proopiomelanocortin and the major stress hormone, corticotropin-releasing hormone (CRH, profoundly altering the “fight or flight” stress system in mother and fetus. As pregnancy progresses, the levels of these stress hormones, including maternal cortisol, increase dramatically. These endocrine changes are important for fetal maturation, but if the levels are altered (e.g., in response to stress, they influence (program the fetal nervous system with long-term consequences. The evidence indicates that fetal exposure to elevated levels of stress hormones (i delays fetal nervous system maturation, (ii restricts the neuromuscular development and alters the stress response of the neonate, (iii impairs mental development and increases fearful behavior in the infant, and (iv may result in diminished gray matter volume in children. The studies reviewed indicate that fetal exposure to stress peptides and hormones exerts profound programming influences on the nervous system and may increase the risk for emotional and cognitive impairment.

  2. ENGINES: exploring single nucleotide variation in entire human genomes

    Directory of Open Access Journals (Sweden)

    Salas Antonio

    2011-04-01

    Full Text Available Abstract Background Next generation ultra-sequencing technologies are starting to produce extensive quantities of data from entire human genome or exome sequences, and therefore new software is needed to present and analyse this vast amount of information. The 1000 Genomes project has recently released raw data for 629 complete genomes representing several human populations through their Phase I interim analysis and, although there are certain public tools available that allow exploration of these genomes, to date there is no tool that permits comprehensive population analysis of the variation catalogued by such data. Description We have developed a genetic variant site explorer able to retrieve data for Single Nucleotide Variation (SNVs, population by population, from entire genomes without compromising future scalability and agility. ENGINES (ENtire Genome INterface for Exploring SNVs uses data from the 1000 Genomes Phase I to demonstrate its capacity to handle large amounts of genetic variation (>7.3 billion genotypes and 28 million SNVs, as well as deriving summary statistics of interest for medical and population genetics applications. The whole dataset is pre-processed and summarized into a data mart accessible through a web interface. The query system allows the combination and comparison of each available population sample, while searching by rs-number list, chromosome region, or genes of interest. Frequency and FST filters are available to further refine queries, while results can be visually compared with other large-scale Single Nucleotide Polymorphism (SNP repositories such as HapMap or Perlegen. Conclusions ENGINES is capable of accessing large-scale variation data repositories in a fast and comprehensive manner. It allows quick browsing of whole genome variation, while providing statistical information for each variant site such as allele frequency, heterozygosity or FST values for genetic differentiation. Access to the data mart

  3. An Investigation of Factors Related to Self-Efficacy for Java Programming among Engineering Students

    Science.gov (United States)

    Askar, Petek; Davenport, David

    2009-01-01

    The purpose of this study was to examine the factors related to self-efficacy for Java programming among first year engineering students. An instrument assessing Java programming self-efficacy was developed from the computer programming self-efficacy scale of Ramalingam & Wiedenbeck. The instrument was administered at the beginning of the…

  4. The Humanistic Side of Engineering: Considering Social Science and Humanities Dimensions of Engineering in Education and Research

    Science.gov (United States)

    Hynes, Morgan; Swenson, Jessica

    2013-01-01

    Mathematics and science knowledge/skills are most commonly associated with engineering's pre-requisite knowledge. Our goals in this paper are to argue for a more systematic inclusion of social science and humanities knowledge in the introduction of engineering to K-12 students. As part of this argument, we present a construct for framing the…

  5. The Rise of Student-to-Student Learning: Youth-led Programs Impacting Engineering Education Globally

    Directory of Open Access Journals (Sweden)

    Julian O'Shea

    2011-07-01

    Full Text Available Around the globe, students and young engineers are playing an increasing role in the coordination and delivery of engineering education programs. Many youth-led initiatives are now conducted with students involved in all aspects of their creation, organisation and delivery. This trend presents an exciting opportunity for the education of engineering students, both those involved in delivery of the courses and for participants. This paper profiles four leading youth-led engineering education programs and analyses their structure and growth in recent years. Profiled are initiatives coordinated by Engineers Without Borders – Australia (EWB-A; the Board of European Students of Technology (BEST; the Electrical Engineering Students’ European Association (EESTEC; and the Student Platform for Engineering Education Development (SPEED. Each case study includes a brief history of the organisation, program overview, growth analysis and future projections. The common features amongst these programs were analysed, as were the aspects which made them distinct from traditional university offerings. Key findings about the initiatives include: an international focus; the mixture of formal learning and social aspects; an integral role of volunteers within the organisation; the use of residential programs; and the role of internal professional development of committee members and volunteers. Additionally, this paper outlines the benefits for universities and provides a guide for how engineering faculties can support and nurture these initiatives and effectively create partnerships.

  6. 2015 Space Human Factors Engineering Standing Review Panel

    Science.gov (United States)

    Steinberg, Susan

    2015-01-01

    The 2015 Space Human Factors Engineering (SHFE) Standing Review Panel (from here on referred to as the SRP) met for a site visit in Houston, TX on December 2 - 3, 2015. The SRP reviewed the updated research plans for the Risk of Inadequate Design of Human and Automation/Robotic Integration (HARI Risk), the Risk of Inadequate Human-Computer Interaction (HCI Risk), and the Risk of Inadequate Mission, Process and Task Design (MPTask Risk). The SRP also received a status update on the Risk of Incompatible Vehicle/Habitat Design (Hab Risk) and the Risk of Performance Errors Due to Training Deficiencies (Train Risk). The SRP is pleased with the progress and responsiveness of the SHFE team. The presentations were much improved this year. The SRP is also pleased with the human-centered design approach. Below are some of the more extensive comments from the SRP. We have also made comments in each section concerning gaps/tasks in each. The comments below reflect more significant changes that impact more than just one particular section.

  7. Abstract: Rwanda Human Resources for Health Program: Genesis ...

    African Journals Online (AJOL)

    Abstract: Rwanda Human Resources for Health Program: Genesis and Evolution ... a program to dramatically improve nursing and midwifery education and practice. ... academic institutions requires flexibility, respect, and thoughtful planning.

  8. Linking Engineering and Medical Training: A USC program seeks to introduce medical and engineering students to medical device development.

    Science.gov (United States)

    Tolomiczenko, George; Sanger, Terry

    2015-01-01

    Medical students are attracted by the prospect of a meaningful addition to their clinical work. Engineering students are excited by a unique opportunity to learn directly alongside their medical student peers. For both, as well as the scientific community at large, the boutique program at the University of Southern California (USC) linking engineering and medical training at the graduate level is instructive of a new way of approaching engineering education that can potentially provide benefits to both students and society. Students who have grown up in an era of ?mass customization? in the retail and service industries can enjoy that same degree of flexibility also in the realm of education. At the same time, society gains engineers who have developed an increased empathy and awareness of the clinical contexts in which their innovations will be implemented.

  9. Martian Surface Boundary Layer Characterization: Enabling Environmental Data for Science, Engineering and Human Exploration

    Science.gov (United States)

    England, C.

    2000-01-01

    For human or large robotic exploration of Mars, engineering devices such as power sources will be utilized that interact closely with the Martian environment. Heat sources for power production, for example, will use the low ambient temperature for efficient heat rejection. The Martian ambient, however, is highly variable, and will have a first order influence on the efficiency and operation of all large-scale equipment. Diurnal changes in temperature, for example, can vary the theoretical efficiency of power production by 15% and affect the choice of equipment, working fluids, and operating parameters. As part of the Mars Exploration program, missions must acquire the environmental data needed for design, operation and maintenance of engineering equipment including the transportation devices. The information should focus on the variability of the environment, and on the differences among locations including latitudes, altitudes, and seasons. This paper outlines some of the WHY's, WHAT's and WHERE's of the needed data, as well as some examples of how this data will be used. Environmental data for engineering design should be considered a priority in Mars Exploration planning. The Mars Thermal Environment Radiator Characterization (MTERC), and Dust Accumulation and Removal Technology (DART) experiments planned for early Mars landers are examples of information needed for even small robotic missions. Large missions will require proportionately more accurate data that encompass larger samples of the Martian surface conditions. In achieving this goal, the Mars Exploration program will also acquire primary data needed for understanding Martian weather, surface evolution, and ground-atmosphere interrelationships.

  10. Martian Surface Boundary Layer Characterization: Enabling Environmental Data for Science, Engineering and Human Exploration

    Science.gov (United States)

    England, C.

    2000-01-01

    For human or large robotic exploration of Mars, engineering devices such as power sources will be utilized that interact closely with the Martian environment. Heat sources for power production, for example, will use the low ambient temperature for efficient heat rejection. The Martian ambient, however, is highly variable, and will have a first order influence on the efficiency and operation of all large-scale equipment. Diurnal changes in temperature, for example, can vary the theoretical efficiency of power production by 15% and affect the choice of equipment, working fluids, and operating parameters. As part of the Mars Exploration program, missions must acquire the environmental data needed for design, operation and maintenance of engineering equipment including the transportation devices. The information should focus on the variability of the environment, and on the differences among locations including latitudes, altitudes, and seasons. This paper outlines some of the WHY's, WHAT's and WHERE's of the needed data, as well as some examples of how this data will be used. Environmental data for engineering design should be considered a priority in Mars Exploration planning. The Mars Thermal Environment Radiator Characterization (MTERC), and Dust Accumulation and Removal Technology (DART) experiments planned for early Mars landers are examples of information needed for even small robotic missions. Large missions will require proportionately more accurate data that encompass larger samples of the Martian surface conditions. In achieving this goal, the Mars Exploration program will also acquire primary data needed for understanding Martian weather, surface evolution, and ground-atmosphere interrelationships.

  11. Clean Diesel Engine Component Improvement Program Diesel Truck Thermoelectric Generator

    Energy Technology Data Exchange (ETDEWEB)

    Elsner, N. B. [Hi-Z Technology, Inc., San Diego, CA (United States); Bass, J. C. [Hi-Z Technology, Inc., San Diego, CA (United States); Ghamaty, S. [Hi-Z Technology, Inc., San Diego, CA (United States); Krommenhoek, D. [Hi-Z Technology, Inc., San Diego, CA (United States); Kushch, A. [Hi-Z Technology, Inc., San Diego, CA (United States); Snowden, D. [Hi-Z Technology, Inc., San Diego, CA (United States); Marchetti, S. [Hi-Z Technology, Inc., San Diego, CA (United States)

    2005-03-16

    Hi-Z Technology, Inc. (Hi-Z) is currently developing four different auxiliary generator designs that are used to convert a portion (5 to 20%) of the waste heat from vehicle engines exhaust directly to electricity. The four designs range from 200 Watts to 10 kW. The furthest along is the 1 kW Diesel Truck Thermoelectric Generator (DTTEG) for heavy duty Class 8 Diesel trucks, which, under this program, has been subjected to 543,000 equivalent miles of bouncing and jarring on PACCAR's test track. Test experience on an earlier version of the DTTEG on the same track showed the need for design modifications incorporated in DTTEG Mod 2, such as a heavy duty shock mounting system and reinforcement of the electrical leads mounting system, the thermocouple mounting system and the thermoelectric module restraints. The conclusion of the 543,000 mile test also pointed the way for an upgrading to heavy duty hose or flex connections for the internal coolant connections for the TEG, and consideration of a separate lower temperature cooling loop with its own radiator. Fuel savings of up to $750 per year and a three to five year payback are believed to be possible with the 5 % efficiency modules. The economics are expected to improve considerably to approach a two year payback when the 5 kW to 10 kW generators make it to the market in a few years with a higher efficiency (20%) thermoelectric module system called Quantum Wells, which are currently under development by Hi-Z. Ultimately, as automation takes over to reduce material and labor costs in the high volume production of QW modules, a one year payback for the 5 kW to10 kW generator appears possible. This was one of the stated goals at the beginning of the project. At some future point in time, with the DTTEG becoming standard equipment on all trucks and automobiles, fuel savings from the 25% conversion of exhaust heat to useable electricity nationwide equates to a 10% reduction in the 12 to 15 million barrels per day of

  12. In Genes We Trust: Germline Engineering, Eugenics, and the Future of the Human Genome.

    Science.gov (United States)

    Powell, Russell

    2015-12-01

    Liberal proponents of genetic engineering maintain that developing human germline modification technologies is morally desirable because it will result in a net improvement in human health and well-being. Skeptics of germline modification, in contrast, fear evolutionary harms that could flow from intervening in the human germline, and worry that such programs, even if well intentioned, could lead to a recapitulation of the scientifically and morally discredited projects of the old eugenics. Some bioconservatives have appealed as well to the value of retaining our "given" human biological nature as a reason for restraining the development and use of human genetic modification technologies even where they would tend to increase well-being. In this article, I argue that germline intervention will be necessary merely to sustain the levels of genetic health that we presently enjoy for future generations-a goal that should appeal to bioliberals and bioconservatives alike. This is due to the population-genetic consequences of relaxed selection pressures in human populations caused by the increasing efficacy and availability of conventional medicine. This heterodox conclusion, which I present as a problem of intergenerational justice, has been overlooked in medicine and bioethics due to certain misconceptions about human evolution, which I attempt to rectify, as well as the sordid history of Darwinian approaches to medicine and social policy, which I distinguish from the present argument.

  13. NASA/American Society for Engineering Education (ASEE) Summer Faculty Fellowship Program 1992

    Science.gov (United States)

    Spencer, John H. (Compiler)

    1992-01-01

    Since 1964, the National Aeronautics and Space Administration (NASA) has supported a program of summer faculty fellowships for engineering and science educators. In a series of collaborations between NASA research and development centers and nearby universities, engineering faculty members spend 10 weeks working with professional peers on research. The Summer Faculty Program Committee of the American Society for Engineering Education supervises the programs. Objectives of the program are (1) to further the professional knowledge of qualified engineering and science faculty members; (2) to stimulate and exchange ideas between participants and NASA; (3) to enrich and refresh the research and teaching activities of participants' institutions; and (4) to contribute to the research objectives of the NASA center.

  14. The Role of Entrepreneurship Program Models and Experiential Activities on Engineering Student Outcomes

    Science.gov (United States)

    Duval-Couetil, Nathalie; Shartrand, Angela; Reed, Teri

    2016-01-01

    Entrepreneurship education is being delivered to greater numbers of engineering students through a variety of courses, programs, and experiential learning activities. Some of these opportunities are designed primarily to serve engineering students in their departments and colleges, while others are cross-campus, university-wide efforts to serve…

  15. Incorporating Molecular and Cellular Biology into a Chemical Engineering Degree Program

    Science.gov (United States)

    O'Connor, Kim C.

    2005-01-01

    There is a growing need for a workforce that can apply engineering principles to molecular based discovery and product development in the biological sciences. To this end, Tulane University established a degree program that incorporates molecular and cellular biology into the chemical engineering curriculum. In celebration of the tenth anniversary…

  16. A Pre-Engineering Program Using Robots to Attract Underrepresented High School and Community College Students

    Science.gov (United States)

    Mosley, Pauline Helen; Liu, Yun; Hargrove, S. Keith; Doswell, Jayfus T.

    2010-01-01

    This paper gives an overview of a new pre-engineering program--Robotics Technician Curriculum--that uses robots to solicit underrepresented students pursuing careers in science, technology, engineering, and mathematics (STEM). The curriculum uses a project-based learning environment, which consists of part lecture and part laboratory. This program…

  17. FWP executive summaries: basic energy sciences materials sciences and engineering program (SNL/NM).

    Energy Technology Data Exchange (ETDEWEB)

    Samara, George A.; Simmons, Jerry A.

    2006-07-01

    This report presents an Executive Summary of the various elements of the Materials Sciences and Engineering Program which is funded by the Division of Materials Sciences and Engineering, Office of Basic Energy Sciences, U.S. Department of Energy at Sandia National Laboratories, New Mexico. A general programmatic overview is also presented.

  18. A Successful Experience of ABET Accreditation of an Electrical Engineering Program

    Science.gov (United States)

    Al-Yahya, S. A.; Abdel-Halim, M. A.

    2013-01-01

    The procedures followed and the various factors that led to the ABET accreditation of the College of Engineering, Qassim University, Buraidah, Saudi Arabia, are illustrated and evaluated for the benefit of other similar colleges. Taking the Electrical Engineering (EE) program as an example, this paper describes the procedures followed to implement…

  19. Minimum time acceleration of aircraft turbofan engines by using an algorithm based on nonlinear programming

    Science.gov (United States)

    Teren, F.

    1977-01-01

    Minimum time accelerations of aircraft turbofan engines are presented. The calculation of these accelerations was made by using a piecewise linear engine model, and an algorithm based on nonlinear programming. Use of this model and algorithm allows such trajectories to be readily calculated on a digital computer with a minimal expenditure of computer time.

  20. An Interactive Simulator-Based Pedagogical (ISP) Approach for Teaching Microcontrollers in Engineering Programs

    Science.gov (United States)

    Tang, Shensheng

    2014-01-01

    Microcontrollers is a required course in most Electrical, Computer, and Mechanic Engineering (Technology) programs at U.S. universities. Most engineering courses (e.g., microcontrollers), by nature, introduce abstract concepts, definitions, and models, and use primarily lectures and readings (words, symbols) to transmit information. This…

  1. Blended Teaching and Learning of Computer Programming Skills in Engineering Curricula

    Science.gov (United States)

    El-Zein, Abbas; Langrish, Tim; Balaam, Nigel

    2009-01-01

    Many engineering schools include computer programming as part of a first-year course taught to large engineering classes. This approach is effective in rationalizing resources and improving the cost-effectiveness of course delivery. In addition, it can lead to wholesale improvements in teaching and learning. However, class sizes and the variety of…

  2. Classical Fortran programming for engineering and scientific applications

    CERN Document Server

    Kupferschmid, Michael

    2009-01-01

    IntroductionWhy Study Programming?The Evolution of FORTRANWhy Study FORTRAN?Classical FORTRANAbout This BookAdvice to InstructorsAbout the AuthorAcknowledgmentsDisclaimersHello, World!Case Study: A First FORTRAN ProgramCompiling the ProgramRunning a Program in UNIXOmissionsExpressions and Assignment StatementsConstantsVariables and Variable NamesArithmetic OperatorsFunction ReferencesExpressionsA

  3. DoD Educational Intervention Programs for Scientists and Engineers.

    Science.gov (United States)

    1995-10-01

    etc.) Tuition assistance for Summer faculty (research) 3 S&E :ance for Internships for S&E ohool Programs for Programs for 3 for HBCU/MIs...centrally-managed endeavor. The programs do not employ mentors, as do the best high school apprenticeship programs and some college internship and work...0430 Botany 0 12 12 GS-0434 Plant Pathology 0 0 0 GS-0435 Plant Physiology 0 0 0 GS-0436 Plant Protection & Quarantine 0 9 9 GS-0437 Horticulture 0 1

  4. NASA/American Society for Engineering Education (ASEE) Summer Faculty Fellowship Program, 1990

    Science.gov (United States)

    Spencer, John H. (Compiler)

    1990-01-01

    Since 1964, NASA has supported a program of summer faculty fellowships for engineering and science educators. The objectives are to further the professional knowledge of qualified engineering and science members; to stimulate and exchange ideas between participants and NASA; to enrich and refresh the research and teaching activities of participants' institutions; and to contribute to the research objectives of the NASA center. The study program consists of lectures and seminars on topics of interest or that are directly relevant to the research topics.

  5. Updating Human Factors Engineering Guidelines for Conducting Safety Reviews of Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    O, J.M.; Higgins, J.; Stephen Fleger - NRC

    2011-09-19

    The U.S. Nuclear Regulatory Commission (NRC) reviews the human factors engineering (HFE) programs of applicants for nuclear power plant construction permits, operating licenses, standard design certifications, and combined operating licenses. The purpose of these safety reviews is to help ensure that personnel performance and reliability are appropriately supported. Detailed design review procedures and guidance for the evaluations is provided in three key documents: the Standard Review Plan (NUREG-0800), the HFE Program Review Model (NUREG-0711), and the Human-System Interface Design Review Guidelines (NUREG-0700). These documents were last revised in 2007, 2004 and 2002, respectively. The NRC is committed to the periodic update and improvement of the guidance to ensure that it remains a state-of-the-art design evaluation tool. To this end, the NRC is updating its guidance to stay current with recent research on human performance, advances in HFE methods and tools, and new technology being employed in plant and control room design. This paper describes the role of HFE guidelines in the safety review process and the content of the key HFE guidelines used. Then we will present the methodology used to develop HFE guidance and update these documents, and describe the current status of the update program.

  6. Citizens, Scholars and the Humanities: An Introduction to State Humanities Programs. Federation Resources 1.

    Science.gov (United States)

    Weiland, Steven, Ed.

    This collection of essays seeks to offer a composite portrait of state humanities programs from a wide range of viewpoints. Topics explored include: the role of the National Endowment for the Humanities; the importance of the humanities; origins and new directions for state programs; humanities and the issues of public policy, the arts, science,…

  7. Engineer Ethics Education that Treated Safety Problem to Promote Development of General Human Competence and Independent Engineer

    Science.gov (United States)

    Hotta, Genji

    The human race came to expect the engineer‧s international activity by an international extension of the risk. The engineer should provide with “Overall ability” and “Independent ability” to answer the demand of the society. The engineer ethics education is effective to the acquisition of the ability that the society demands. Because the engineer ethics education teaches the engineer to develop “Ethics action as the individual” to “Ethics activity as the enterprise” . In the point of development of the comprehensive capacity, it can be said that the engineer ethics education is training that supports the action power that accomplishes the social responsibility. However, it is easy to make the engineer ethics education a polite fiction. Then, we propose to take the safety problem to the ethics education for the prevention of making to the polite fiction of the education.

  8. Assessment of the Human Morphophysiology Program for Training Biomedical Equipment Technologists

    Directory of Open Access Journals (Sweden)

    Concepción Gómez Rives

    2014-04-01

    Full Text Available Background: there are a series of questions related to the Human Morphophysiology program, which are posed in different teaching and methodological events, both through the analysis of the methodological work performed in the discipline and the agents involved in the teaching-learning process. Objective: to assess the Human Morphophysiology program for training Biomedical Equipment Technologists. Methods: a qualitative and quantitative exploratory study was conducted with all students enrolled in Clinical Engineering studies during the 2006-2007 and 2007-2008 academic years and 14 professors from the University of Medical Sciences in Matanzas. In addition to the document review, students and teachers were surveyed. Results: identified weaknesses of the program included: not justifying the discipline in the Clinical Engineering curriculum; not establishing a correspondence between the discipline and the graduate profile; not setting a horizontal or vertical structure in the curriculum; not including all components of the teaching-learning process in the curriculum design with sufficient accuracy; not reflecting ways to develop student leadership. Conclusion: the assessments of students and teachers show the weaknesses of the program, which compromise the quality of the teaching-learning process of the discipline of Human Morphophysiology as part of the Clinical Engineering curriculum.

  9. Human Services Program Evaluation: "How to Improve Your Accountability and Program Effectiveness"

    Science.gov (United States)

    Barrett, Thomas; Sorensen, James

    2015-01-01

    The term "outcome evaluation" has become one of the most popular terms among human service providers and those whose job it is to evaluate the impact of human service programs. In the public sector alone, there are over a hundred instruments in use to evaluate the impact of state human service programs. Most states, many providers, and…

  10. Human Power Vehicle Program. Final report, June 15, 1993--June 14, 1995

    Energy Technology Data Exchange (ETDEWEB)

    Crowell, J.; Graves, P.

    1995-11-01

    The Human Power Vehicle Program was an intensive, five day a week, four week program designed to give middle school students the opportunity to ``be engineers``. During the month of July, Delta College, the Macro Michigan Multicultural Pre-Technical Education Partnership (M3PEP), and the United States Department of Energy sponsored a four-week learning experience in human-powered vehicles. This unique experience introduced students to the physiology of exercise, the mechanics of the bicycle, and the physics and mathematics of the bicycle. Students also participated in a three day bike tour. The Program used the Bike Lab facility at Delta College`s International Centre in Saginaw, Michigan. Students had the opportunity to explore the development and refinement of the bicycle design and to investigate it`s power machine-the human body. Interactive instruction was conducted in groups to assure that all students experienced the satisfaction of understanding the bicycle. The purpose of the Program was to increase minority students` awareness and appreciation of mathematics and science. The premise behind the Program was that engineers and scientists are made, not born. The Program was open to all minority youth, grades 8 and 9, and was limited to 25 students. Students were selected to participate based upon their interest, desire, maturity, and attitude.

  11. Reverse engineering human neurodegenerative disease using pluripotent stem cell technology.

    Science.gov (United States)

    Liu, Ying; Deng, Wenbin

    2016-05-01

    With the technology of reprogramming somatic cells by introducing defined transcription factors that enables the generation of "induced pluripotent stem cells (iPSCs)" with pluripotency comparable to that of embryonic stem cells (ESCs), it has become possible to use this technology to produce various cells and tissues that have been difficult to obtain from living bodies. This advancement is bringing forth rapid progress in iPSC-based disease modeling, drug screening, and regenerative medicine. More and more studies have demonstrated that phenotypes of adult-onset neurodegenerative disorders could be rather faithfully recapitulated in iPSC-derived neural cell cultures. Moreover, despite the adult-onset nature of the diseases, pathogenic phenotypes and cellular abnormalities often exist in early developmental stages, providing new "windows of opportunity" for understanding mechanisms underlying neurodegenerative disorders and for discovering new medicines. The cell reprogramming technology enables a reverse engineering approach for modeling the cellular degenerative phenotypes of a wide range of human disorders. An excellent example is the study of the human neurodegenerative disease amyotrophic lateral sclerosis (ALS) using iPSCs. ALS is a progressive neurodegenerative disease characterized by the loss of upper and lower motor neurons (MNs), culminating in muscle wasting and death from respiratory failure. The iPSC approach provides innovative cell culture platforms to serve as ALS patient-derived model systems. Researchers have converted iPSCs derived from ALS patients into MNs and various types of glial cells, all of which are involved in ALS, to study the disease. The iPSC technology could be used to determine the role of specific genetic factors to track down what's wrong in the neurodegenerative disease process in the "disease-in-a-dish" model. Meanwhile, parallel experiments of targeting the same specific genes in human ESCs could also be performed to control

  12. Enhancing the Programming Experience for First-Year Engineering Students through Hands-On Integrated Computer Experiences

    Science.gov (United States)

    Canfield, Stephen L.; Ghafoor, Sheikh; Abdelrahman, Mohamed

    2012-01-01

    This paper describes the redesign and implementation of the course, "Introduction to Programming for Engineers" using microcontroller (MCU) hardware as the programming target. The objective of this effort is to improve the programming competency for engineering students by more closely relating the initial programming experience to the student's…

  13. Enhancing the Programming Experience for First-Year Engineering Students through Hands-On Integrated Computer Experiences

    Science.gov (United States)

    Canfield, Stephen L.; Ghafoor, Sheikh; Abdelrahman, Mohamed

    2012-01-01

    This paper describes the redesign and implementation of the course, "Introduction to Programming for Engineers" using microcontroller (MCU) hardware as the programming target. The objective of this effort is to improve the programming competency for engineering students by more closely relating the initial programming experience to the student's…

  14. Teamwork and Robot Competitions in the Undergraduate Program at the Copenhagen University College of Engineering

    Science.gov (United States)

    Friesel, Anna

    In today’s industry and trade, there is an increasing demand for engineers who don’t just have excellent competence in their field of specialization but also a good understanding and practical experience in working with engineering projects, and working as members of a team. These subjects are usually not adequately addressed in engineering degree programs. This paper describes our experience in teaching mathematical modeling, control theory, microprocessors, programming, digital and analogue electronics as part of a robot design project. Robot competition at the end of semester motivates students to study theoretical disciplines. The pass rate compared to the classical courses increased from 60-70% to 85-95%.

  15. Status report - DARPA/NASA convertible turbofan/turboshaft engine program

    Science.gov (United States)

    Bellin, A. I.; Brooks, A.

    1983-01-01

    A development status report is presented for the NASA/Defense Advanced Research Projects Agency convertible turbofan-turboshaft engine, which can power a high speed rotorcraft in vertical flight, as well as in horizontal flight up to speeds of Mach 0.85. The basis for this development program is a modified TF34-GE-400 engine. Program objectives include both the demonstration of dual output mode (jet thrust and shaft horsepower) capability and the development of a control system which will operate the engine in either mode and convert operation between the modes.

  16. NASA/American Society for Engineering Education (ASEE) Summer Faculty Fellowship Program, 1991

    Science.gov (United States)

    Tiwari, Surendra N. (Compiler)

    1991-01-01

    In a series of collaborations between NASA research and development centers and nearby universities, engineering faculty members spent 10 weeks working with professional peers on research. The Summer Faculty Program Committee of the American Society of Engineering Education supervises the programs. The objects were the following: (1) to further the professional knowledge of qualified engineering and science faculty members; (2) to stimulate and exchange ideas between participants and NASA; (3) to enrich and refresh the research and teaching activities of the participants' institutions; and (4) to contribute to the research objectives of the NASA center.

  17. 1997 NASA-ODU American Society for Engineering Education (ASEE) Summer Faculty Fellowship Program

    Science.gov (United States)

    Tiwari, Surendra N. (Compiler); Young, Deborah B. (Compiler)

    1998-01-01

    Since 1964, the National Aeronautics and Space Administration (NASA) has supported a program of summer faculty fellowships for engineering and science educators. In a series of collaborations between NASA research and development centers and nearby universities, engineering faculty members spend 10 weeks working with professional peers on research. The Summer Faculty Program Committee of the American Society for Engineering Education supervises the programs. Objectives of the program are as follows: (1) To further the professional knowledge of qualified engineering and science faculty members, (2) To stimulate and exchange ideas between participants and NASA; (3) To enrich and refresh the research and teaching activities of participants' institutions; and (4) To contribute to the research objectives of the NASA center. Program description is as follows: College or university faculty members will be appointed as Research Fellows to spend 10 weeks in cooperative research and study at the NASA Langley Research Center. The Fellow will devote approximately 90 percent of the time to a research problem and the remaining time to a study program. The study program will consist of lectures and seminars on topics of interest or that are directly relevant to the Fellows' research topics. The lectures and seminar leaders will be distinguished scientists and engineers from NASA, education, and industry.

  18. A concept for a bachelor program in electrical engineering

    DEFF Research Database (Denmark)

    Niemann, Hans Henrik

    2011-01-01

    The main concept for the Bachelor of Science in Engineering (BScE) in electrical engineering at Technical University of Denmark (DTU) will be described in this paper. A new curriculum was introduced from the start of the autumn semester in 2010. The curriculum was the result of more than one year...... of work with first description of competences followed by a more detailed description of the single main areas. Finally, the new study plan was implemented through a number of courses satisfying some general rules for bachelor study plans....

  19. NRC Reviewer Aid for Evaluating the Human Factors Engineering Aspects of Small Modular Reactors

    Energy Technology Data Exchange (ETDEWEB)

    OHara J. M.; Higgins, J.C.

    2012-01-13

    Small modular reactors (SMRs) are a promising approach to meeting future energy needs. Although the electrical output of an individual SMR is relatively small compared to that of typical commercial nuclear plants, they can be grouped to produce as much energy as a utility demands. Furthermore, SMRs can be used for other purposes, such as producing hydrogen and generating process heat. The design characteristics of many SMRs differ from those of current conventional plants and may require a distinct concept of operations (ConOps). The U.S. Nuclear Regulatory Commission (NRC) conducted research to examine the human factors engineering (HFE) and the operational aspects of SMRs. The research identified thirty potential human-performance issues that should be considered in the NRC's reviews of SMR designs and in future research activities. The purpose of this report is to support NRC HFE reviewers of SMR applications by identifying some of the questions that can be asked of applicants whose designs have characteristics identified in the issues. The questions for each issue were identified and organized based on the review elements and guidance contained in Chapter 18 of the Standard Review Plan (NUREG-0800), and the Human Factors Engineering Program Review Model (NUREG-0711).

  20. Dragonfly: strengthening programming skills by building a game engine from scratch

    Science.gov (United States)

    Claypool, Mark

    2013-06-01

    Computer game development has been shown to be an effective hook for motivating students to learn both introductory and advanced computer science topics. While games can be made from scratch, to simplify the programming required game development often uses game engines that handle complicated or frequently used components of the game. These game engines present the opportunity to strengthen programming skills and expose students to a range of fundamental computer science topics. While educational efforts have been effective in using game engines to improve computer science education, there have been no published papers describing and evaluating students building a game engine from scratch as part of their course work. This paper presents the Dragonfly-approach in which students build a fully functional game engine from scratch and make a game using their engine as part of a junior-level course. Details on the programming projects are presented, as well as an evaluation of the results from two offerings that used Dragonfly. Student performance on the projects as well as student assessments demonstrates the efficacy of having students build a game engine from scratch in strengthening their programming skills.

  1. Explicating Practicum Program Theory: A Case Example in Human Ecology

    Science.gov (United States)

    Chandler, Kathryn M. M.; Williamson, Deanna L.

    2013-01-01

    This study explicated the theory underpinning the Human Ecology Practicum Program offered in the Department of Human Ecology at the University of Alberta. The program has operated for 40 years but never been formally evaluated. Using a document analysis, focus group and individual interviews, and a stakeholder working group, we explored…

  2. Explicating Practicum Program Theory: A Case Example in Human Ecology

    Science.gov (United States)

    Chandler, Kathryn M. M.; Williamson, Deanna L.

    2013-01-01

    This study explicated the theory underpinning the Human Ecology Practicum Program offered in the Department of Human Ecology at the University of Alberta. The program has operated for 40 years but never been formally evaluated. Using a document analysis, focus group and individual interviews, and a stakeholder working group, we explored…

  3. Systems engineering programs for geologic nuclear waste disposal

    Energy Technology Data Exchange (ETDEWEB)

    Klett, R. D.; Hertel, Jr., E. S.; Ellis, M. A.

    1980-06-01

    The design sequence and system programs presented begin with general approximate solutions that permit inexpensive analysis of a multitude of possible wastes, disposal media, and disposal process properties and configurations. It then continues through progressively more precise solutions as parts of the design become fixed, and ends with repository and waste form optimization studies. The programs cover both solid and gaseous waste forms. The analytical development, a program listing, a users guide, and examples are presented for each program. Sensitivity studies showing the effects of disposal media and waste form thermophysical properties and repository layouts are presented as examples.

  4. Human serum provided additional values in growth factors supplemented medium for human chondrocytes monolayer expansion and engineered cartilage construction.

    Science.gov (United States)

    Chua, K H; Aminuddin, B S; Fuzina, N H; Ruszymah, B H I

    2004-05-01

    We have previously formulated an optimized human chondrocytes growth medium based on 2% fetal bovine serum supplementation. For clinical usage, the animal serum must be replaced by patient own serum. We investigated the effects of human serum concentration for human nasal septum chondrocytes monolayer culture and cartilage reconstruction. Human serum demonstrated a dose dependent manner in promoting chondrocytes growth and cartilage engineering.

  5. Dynamic programming for Integrated Emission Management in diesel engines

    NARCIS (Netherlands)

    Schijndel, J. van; Donkers, M.C.F.; Willems, F.P.T.; Heemels, W.P.M.H.

    2014-01-01

    Integrated Emission Management (IEM) is a supervisory control strategy that aims at minimizing the operational costs of diesel engines with an aftertreatment system, while satisfying emission constraints imposed by legislation. In previous work on IEM, a suboptimal real-time implementable solution w

  6. Web-Based Engine for Program Curriculum Designers

    Science.gov (United States)

    Hamam, H.; Loucif, S.

    2009-01-01

    Educational institutions pay careful attention to the design of program curricula, which represent a framework to meet institutional goals and missions. Of course, the success of any institution depends highly on the quality of its program curriculum. The development of such a curriculum and, more importantly, the evaluation of its quality are…

  7. Recruitment Strategies Aiming to Attract Females into Undergraduate Engineering Programs: Examining Their Role and Use

    Science.gov (United States)

    Howenstine, Julie Anne

    2013-01-01

    By 2009, the percentage of women who graduated with general undergraduate degrees had increased to almost 58% of all students who completed 4-year degree programs (National Center for Education Statistics, 2009a). These percentages, however, have not been reflected in the enrollment rates of females into undergraduate engineering programs. In…

  8. The Civil Engineering Graduate Program at PUC-Rio: A Brazilian Experience.

    Science.gov (United States)

    Romanel, Celso; Filho, Jose Napoleao

    This document discusses the graduate programs in civil engineering at the Pontifical Catholic University of Rio de Janeiro, Brazil, the oldest Brazilian private university. The report features discussions of faculty member backgrounds, trends in student enrollment, women's participation in the program, degree completion, student origins,…

  9. Fifth Grade Students' Understanding of Ratio and Proportion in an Engineering Robotics Program

    Science.gov (United States)

    Ortiz, Araceli Martinez

    2010-01-01

    The research described in this dissertation explores the impact of utilizing a LEGO-robotics integrated engineering and mathematics program to support fifth grade students' learning of ratios and proportion in an extracurricular program. The research questions guiding this research study were (1) how do students' test results compare for students…

  10. A Self-Ethnographic Investigation of Continuing Education Program in Engineering Arising from Economic Structural Change

    Science.gov (United States)

    Kaihlavirta, Auri; Isomöttönen, Ville; Kärkkäinen, Tommi

    2015-01-01

    This paper provides a self-ethnographic investigation of a continuing education program in engineering in Central Finland. The program was initiated as a response to local economic structural change, in order to offer re-education possibilities for a higher educated workforce currently under unemployment threat. We encountered considerable…

  11. Aspects on Teaching/Learning with Object Oriented Programming for Entry Level Courses of Engineering.

    Science.gov (United States)

    de Oliveira, Clara Amelia; Conte, Marcos Fernando; Riso, Bernardo Goncalves

    This work presents a proposal for Teaching/Learning, on Object Oriented Programming for Entry Level Courses of Engineering and Computer Science, on University. The philosophy of Object Oriented Programming comes as a new pattern of solution for problems, where flexibility and reusability appears over the simple data structure and sequential…

  12. 34 CFR 637.3 - What regulations apply to the Minority Science and Engineering Improvement Program?

    Science.gov (United States)

    2010-07-01

    ... Engineering Improvement Program? 637.3 Section 637.3 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION MINORITY SCIENCE AND... Department Regulations). (4) 34 CFR part 79 (Intergovernmental Review of Department of Education Programs...

  13. Final Report on National Science Foundation "Women in Engineering Program," July 1, 1976-July 8, 1978.

    Science.gov (United States)

    Dorf, Richard C.

    Objectives and results are given of a program designed to prepare women for employment in engineering at a level comparable to current B.S. graduates. The program endeavored to create a learning situation in which rigorous academic standards would be maintained, while at the same time taking into account the realities of the lives of re-entry…

  14. An Analysis of Retention Programs for Female Students in Engineering at the University of Toledo

    Science.gov (United States)

    Franchetti, Matthew

    2012-01-01

    This paper summarizes the findings of a five-year study aimed at improving the retention rates of female students pursuing careers in engineering. The study analyzed a series of programs implemented at the University of Toledo. The programs involve hands-on design projects, research experiences, communication tools geared towards females,…

  15. The engineering design integration (EDIN) system. [digital computer program complex

    Science.gov (United States)

    Glatt, C. R.; Hirsch, G. N.; Alford, G. E.; Colquitt, W. N.; Reiners, S. J.

    1974-01-01

    A digital computer program complex for the evaluation of aerospace vehicle preliminary designs is described. The system consists of a Univac 1100 series computer and peripherals using the Exec 8 operating system, a set of demand access terminals of the alphanumeric and graphics types, and a library of independent computer programs. Modification of the partial run streams, data base maintenance and construction, and control of program sequencing are provided by a data manipulation program called the DLG processor. The executive control of library program execution is performed by the Univac Exec 8 operating system through a user established run stream. A combination of demand and batch operations is employed in the evaluation of preliminary designs. Applications accomplished with the EDIN system are described.

  16. 1998 NASA-HU American Society for Engineering Education (ASEE) Summer Faculty Fellowship Program

    Science.gov (United States)

    Marable, William P. (Compiler); Murray, Deborah B. (Compiler)

    1998-01-01

    Since 1964, the National Aeronautics and Space Administration (NASA) has supported a program of summer faculty fellowships for engineering and science educators. In a series of collaborations between NASA research and development centers and nearby universities, engineering faculty members spend 10 weeks working with professional peers on research. The Summer Faculty Program Committee of the American Society for Engineering Education supervises the programs. The program objectives include: (1) To further the professional knowledge of qualified engineering and science faculty members; (2) To stimulate and exchange ideas between participants and NASA; (3) To enrich and refresh the research and teaching activities of participants' institutions; (4) To contribute to the research objectives of the NASA center. College or university faculty members will be appointed as Research Fellows to spend 10 weeks in cooperative research and study at the NASA Langley Research Center. The Fellow will devote approximately 90 percent of the time to a research problem and the remaining time to a study program. The study program will consist of lectures and seminars on topics of interest or that are directly relevant to the Fellows' research topics. The lecture and seminar leaders will be distinguished scientists and engineers from NASA, education, and industry.

  17. 1999 NASA - ODU American Society for Engineering Education (ASEE) Summer Faculty Fellowship Program

    Science.gov (United States)

    Tiwari, Surendra N. (Compiler); Murray, Deborah B. (Compiler)

    2000-01-01

    Since 1964, the National Aeronautics and Space Administration (NASA) has supported a program or summer faculty fellowships for engineering and science educators. In a series of collaborations between NASA research and development centers and nearby universities, engineering faculty members spend 10 weeks working with professional peers on research. The Summer Faculty Program Committee of the American Society for Engineering Education supervises the programs. Objectives: (1) To further the professional knowledge of qualified engineering and science faculty members; (2) To stimulate and exchange ideas between participants and NASA; (3) To enrich and refresh the research and teaching activities of participants' institutions; (4) To contribute to the research objectives of the NASA center. Program Description: College or university faculty members will be appointed as Research Fellows to spend 10 weeks in cooperative research and study at the NASA Langley Research Center. The Fellow will devote approximately 90 percent of the time to a research problem and the remaining time to a study program. The study program will consist of lectures and seminars on topics of interest or that are directly relevant to the Fellows' research topics. The lecture and seminar leaders will be distinguished scientists and engineers from NASA, education, and industry.

  18. Hampton University/American Society for Engineering Education/NASA Summer Faculty Fellowship Program 1986

    Science.gov (United States)

    Spencer, J. H. (Compiler)

    1986-01-01

    Since 1964, the National Aeronautics and Space Administration (NASA) has supported a program of summer faculty fellowships for engineering and science educators. In a series of collaborations between NASA research and development centers and nearby universities, engineering faculty members spend 10 or 11 weeks working with professional peers on research. The Summer Faculty Program Committee of the American Society of Engineering Education supervises the programs. Objectives: (1) To further the professional knowledge of qualified engineering and science faculty members; (2) to stimulate and exchange ideas between participants and NASA; (3) To enrich and refresh the research and teaching activities of participants' institutions; (4) to contribute to the research objectives of the NASA center. Program Description: College or university will be faculty members appointed as Research Fellows to spend 10 weeks in cooperative research and study at the NASA-Langley Research Center. The Fellow will devote approximately 90 percent of the time to a research problem and the remaining time to a study program. The study program will consist of lectures and seminars on topics of general interest or that are directly relevant to the Fellows' research project. The lecturers and seminar leaders will be distinguished scientists and engineers from NASA, education or industry.

  19. 2001 NASA-ODU American Society for Engineering Education (ASEE) Summer Faculty Fellowship Program

    Science.gov (United States)

    Tiwari, Surendra N. (Compiler); Murray, Deborah B. (Compiler); Hathaway, Roger A. (Technical Monitor)

    2002-01-01

    Since 1964, the National Aeronautics and Space Administration (NASA) has supported a program of summer faculty fellowships for engineering and science educators. In a series of collaborations between NASA research and development centers and nearby universities, engineering faculty members spend 10 weeks working with professional peers on research. The Summer Faculty Program Committee of the American Society for Engineering Education supervises these programs. Objectives: (1) To further the professional knowledge of qualified engineering and science faculty members; (2) To stimulate and exchange ideas between participants and NASA; (3) To enrich and refresh the research and teaching activities of participants' institutions; (4 To contribute to the research objectives of the NASA center. Program Description: College or university faculty members will be appointed as Research Fellows to spend 10 weeks in cooperative research and study at the NASA Langley Research Center. The Fellow will devote approximately 90 percent of the time to a research problem and the remaining time to a study program. The study program will consist of lectures and seminars on topics of interest or that are directly relevant to the Fellow's research topics. The lecture and seminar leaders wil be distinguished scientists and engineers from NASA, education and industry.

  20. NASA/American Society for Engineering Education (ASEE) Summer Faculty Fellowship Program, 1985

    Science.gov (United States)

    Goglia, G. (Compiler)

    1985-01-01

    Since 1964, the National Aeronautics and Space Administration (NASA) has supported a program of summer faculty fellowships for engineering and science educators. In a series of collaborations between NASA research and development centers and nearby universities, engineering faculty members spend 10 weeks working with professional peers on research. The Summer Faculty Program Committee of the American Society for Engineering Education supervises the programs. The objectives of this program are: (1) to further the professional knowledge of qualified engineering and science faculty members; (2) to simulate and exchange ideas between participants and NASA; (3) to enrich and refresh the research and teaching activities of participants institutions; and (4) to contribute to the research objectives of the NASA center. College or university faculty members will be appointed as research fellows to spend 10 weeks in cooperative research and study at the NASA Langley Research Center. The fellows will devote approximately 90 percent of the time to a research problem and the remaining time to a study program. The study program will consist of lectures and seminars on topics of general interest or that are directly relevant to the fellows' research project. The lecturers and seminar leaders will be distinguished scientists and engineers from NASA, the educational community, or industry.

  1. 1996 NASA-Hampton University American Society for Engineering Education (ASEE) Summer Faculty Fellowship Program

    Science.gov (United States)

    Spencer, John H. (Compiler); Young, Deborah B. (Compiler)

    1996-01-01

    NASA has supported a program of summer faculty fellowships for engineering and science educators. In a series of collaborations between NASA research and development centers and nearby universities, engineering faculty members spend 10 weeks working with professional peers on research. The Summer Faculty Program Committee of the American Society for Engineering Education supervises the programs. The objectives were: (1) To further the professional knowledge of qualified engineering and science faculty members; (2) To stimulate and exchange ideas between participants and NASA; (3) To enrich and refresh the research and teaching activities of participants institutions; (4) To contribute to the research objectives of the NASA Center. Program Description: College or university faculty members will be appointed as Research Fellows to spend 10 weeks in cooperative research and study at the NASA Langley Research Center. The Fellow will devote approximately 90 percent of the time to a research problem and the remaining time to a study program. The study program will consist of lectures and seminars on topics of interest or that are directly relevant to the Fellows' research topics. The lectures and seminar leaders will be distinguished scientists and engineers from NASA, education, or industry.

  2. Efficient derivation and genetic modifications of human pluripotent stem cells on engineered human feeder cell lines.

    Science.gov (United States)

    Zou, Chunlin; Chou, Bin-Kuan; Dowey, Sarah N; Tsang, Kitman; Huang, Xiaosong; Liu, Cyndi F; Smith, Cory; Yen, Jonathan; Mali, Prashant; Zhang, Yu Alex; Cheng, Linzhao; Ye, Zhaohui

    2012-08-10

    Derivation of pluripotent stem cells (iPSCs) induced from somatic cell types and the subsequent genetic modifications of disease-specific or patient-specific iPSCs are crucial steps in their applications for disease modeling as well as future cell and gene therapies. Conventional procedures of these processes require co-culture with primary mouse embryonic fibroblasts (MEFs) to support self-renewal and clonal growth of human iPSCs as well as embryonic stem cells (ESCs). However, the variability of MEF quality affects the efficiencies of all these steps. Furthermore, animal sourced feeders may hinder the clinical applications of human stem cells. In order to overcome these hurdles, we established immortalized human feeder cell lines by stably expressing human telomerase reverse transcriptase, Wnt3a, and drug resistance genes in adult mesenchymal stem cells. Here, we show that these immortalized human feeders support efficient derivation of virus-free, integration-free human iPSCs and long-term expansion of human iPSCs and ESCs. Moreover, the drug-resistance feature of these feeders also supports nonviral gene transfer and expression at a high efficiency, mediated by piggyBac DNA transposition. Importantly, these human feeders exhibit superior ability over MEFs in supporting homologous recombination-mediated gene targeting in human iPSCs, allowing us to efficiently target a transgene into the AAVS1 safe harbor locus in recently derived integration-free iPSCs. Our results have great implications in disease modeling and translational applications of human iPSCs, as these engineered human cell lines provide a more efficient tool for genetic modifications and a safer alternative for supporting self-renewal of human iPSCs and ESCs.

  3. Tissue-engineered microenvironment systems for modeling human vasculature.

    Science.gov (United States)

    Tourovskaia, Anna; Fauver, Mark; Kramer, Gregory; Simonson, Sara; Neumann, Thomas

    2014-09-01

    The high attrition rate of drug candidates late in the development process has led to an increasing demand for test assays that predict clinical outcome better than conventional 2D cell culture systems and animal models. Government agencies, the military, and the pharmaceutical industry have started initiatives for the development of novel in-vitro systems that recapitulate functional units of human tissues and organs. There is growing evidence that 3D cell arrangement, co-culture of different cell types, and physico-chemical cues lead to improved predictive power. A key element of all tissue microenvironments is the vasculature. Beyond transporting blood the microvasculature assumes important organ-specific functions. It is also involved in pathologic conditions, such as inflammation, tumor growth, metastasis, and degenerative diseases. To provide a tool for modeling this important feature of human tissue microenvironments, we developed a microfluidic chip for creating tissue-engineered microenvironment systems (TEMS) composed of tubular cell structures. Our chip design encompasses a small chamber that is filled with an extracellular matrix (ECM) surrounding one or more tubular channels. Endothelial cells (ECs) seeded into the channels adhere to the ECM walls and grow into perfusable tubular tissue structures that are fluidically connected to upstream and downstream fluid channels in the chip. Using these chips we created models of angiogenesis, the blood-brain barrier (BBB), and tumor-cell extravasation. Our angiogenesis model recapitulates true angiogenesis, in which sprouting occurs from a "parent" vessel in response to a gradient of growth factors. Our BBB model is composed of a microvessel generated from brain-specific ECs within an ECM populated with astrocytes and pericytes. Our tumor-cell extravasation model can be utilized to visualize and measure tumor-cell migration through vessel walls into the surrounding matrix. The described technology can be used

  4. Performance deterioration based on in-service engine data: JT9D jet engine diagnostics program

    Science.gov (United States)

    Sallee, G. P.

    1979-01-01

    Results of analyses of engine performance deterioration trends and levels with respect to service usage are presented. Thirty-two JT9D-7A engines were selected for this purpose. The selection of this engine fleet provided the opportunity of obtaining engine performance data starting before the first flight through initial service such that the trend and levels of engine deterioration related to both short and long term deterioration could be more carefully defined. The performance data collected and analyzed included in-flight, on wing (ground), and test stand prerepair and postrepair performance calibrations with expanded instrumentation where feasible. The results of the analyses of these data were used to: (1) close gaps in previously obtained historical data as well as augment the historical data with more carefully obtained data; (2) refine preliminary models of performance deterioration with respect to usage; (3) establish an understanding of the relationships between ground and altitude performance deterioration trends; (4) refine preliminary recommendations concerning means to reduce and control deterioration; and (5) identify areas where additional effort is required to develop an understanding of complex deterioration issues.

  5. Success in Undergraduate Engineering Programs: A Comparative Analysis by Race and Gender

    Science.gov (United States)

    Lord, Susan

    2010-03-01

    Interest in increasing the number of engineering graduates in the United States and promoting gender equality and diversification of the profession has encouraged considerable research on women and minorities in engineering programs. Drawing on a framework of intersectionality theory, this work recognizes that women of different ethnic backgrounds warrant disaggregated analysis because they do not necessarily share a common experience in engineering education. Using a longitudinal, comprehensive data set of more than 79,000 students who matriculated in engineering at nine universities in the Southeastern United States, this research examines how the six-year graduation rates of engineering students vary by disaggregated combinations of gender and race/ethnicity. Contrary to the popular opinion that women drop out of engineering at higher rates, our results show that Asian, Black, Hispanic, Native American, and White women who matriculate in engineering are as likely as men to graduate in engineering in six years. In fact, Asian, Black, Hispanic, and Native American women engineering matriculants graduate at higher rates than men and there is a small difference for white students. 54 percent of White women engineering matriculants graduate in six-years compared with 53 percent of white men. For male and female engineering matriculants of all races, the most likely destination six years after entering college is graduation within engineering. This work underscores the importance of research disaggregated by race and gender and points to the critical need for more recruitment of women into engineering as the low representation of women in engineering education is primarily a reflection of their low representation at matriculation.

  6. Decomposition techniques in mathematical programming engineering and science applications

    CERN Document Server

    Conejo, Antonio J; Minguez, Roberto; Garcia-Bertrand, Raquel

    2006-01-01

    Optimization plainly dominates the design, planning, operation, and c- trol of engineering systems. This is a book on optimization that considers particular cases of optimization problems, those with a decomposable str- ture that can be advantageously exploited. Those decomposable optimization problems are ubiquitous in engineering and science applications. The book considers problems with both complicating constraints and complicating va- ables, and analyzes linear and nonlinear problems, with and without in- ger variables. The decomposition techniques analyzed include Dantzig-Wolfe, Benders, Lagrangian relaxation, Augmented Lagrangian decomposition, and others. Heuristic techniques are also considered. Additionally, a comprehensive sensitivity analysis for characterizing the solution of optimization problems is carried out. This material is particularly novel and of high practical interest. This book is built based on many clarifying, illustrative, and compu- tional examples, which facilitate the learning p...

  7. Abstracts of the 48. Canadian chemical engineering conference : technical program

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-10-01

    The conference was organized into six concurrent sessions devoted to fluidized bed technology, multi-phase reactors, catalysis, environmental technology, new developments, and biotechnology. A total of 491 papers were presented. Papers of particular interest to energy technology emphasized new technologies and chemical engineering techniques involved in processing petroleum products. Fluidized beds for hydro-treatment and biochemical processing, conversion of biomass to bio-oils and strategies for reducing emissions from Canadian energy facilities were some of the topics addressed.

  8. The collaborative program of research in engineering sciences

    Energy Technology Data Exchange (ETDEWEB)

    White, D.C.

    1989-08-01

    Research programs in the following areas are briefly described: High-Temperature Gas-Particle Reactions; Mathematical Modelling of Plasma Systems; Metal Transfer in Gas Metal-Arc Welding; Multivariable Control of Gas Metal-Arc Welding; Synthesis of Heat and Work Integration Systems for Chemical Process Plants; Parity Simulation of Dynamic Processes; Fundamentals of Elastic-Plastic Fracture: Three-Dimensional and Mechanistic Modelling; and Comminution of Energy Materials. Publications from each program are listed.

  9. Case study: a decade of changes in a small environmental engineering graduate program.

    Science.gov (United States)

    Leung, S W

    2004-01-01

    For a small graduate program in environmental engineering in a rural state in the US, it is important for the program curriculum to stay in the mainstream. While resident student enrollment is approaching a steady level, international student enrollment increases steadily, this is due in part to the out-of-state tuition waiver provided to the students. Part-time students are a significant part of the program, these students have special needs that are different from traditional full-time students that must be taken into consideration in program planning. A small program provides an attentive atmosphere for students' learning, but it also has problems that a larger program would not encounter, such as competitiveness, personal conflicts, program identity, etc. Despite success in the past, the program is likely to merge with other related programs in the university during times of budget restrictions.

  10. American Society for Engineering Education/NASA Summer Faculty Fellowship Program 1982

    Science.gov (United States)

    Spencer, J. H. (Compiler)

    1983-01-01

    A program of summer faculty fellowships for engineering and science educators is described. The program involves participation in cooperative research and study. Results of the program evaluation are summarized. The research fellows indicated satisfaction with the program. Benefits of the program cited include: (1) enhancement of professional abilities; (2) contact with professionals in a chosen area of research; (3) familiarity with research facilities; and (4) development of new research techniques and their adaptation to an academic setting. Abstracts of each of the research projects undertaken are presented.

  11. Human Research Program Integrated Research Plan. Revision A January 2009

    Science.gov (United States)

    2009-01-01

    The Integrated Research Plan (IRP) describes the portfolio of Human Research Program (HRP) research and technology tasks. The IRP is the HRP strategic and tactical plan for research necessary to meet HRP requirements. The need to produce an IRP is established in HRP-47052, Human Research Program - Program Plan, and is under configuration management control of the Human Research Program Control Board (HRPCB). Crew health and performance is critical to successful human exploration beyond low Earth orbit. The Human Research Program (HRP) is essential to enabling extended periods of space exploration because it provides knowledge and tools to mitigate risks to human health and performance. Risks include physiological and behavioral effects from radiation and hypogravity environments, as well as unique challenges in medical support, human factors, and behavioral or psychological factors. The Human Research Program (HRP) delivers human health and performance countermeasures, knowledge, technologies and tools to enable safe, reliable, and productive human space exploration. Without HRP results, NASA will face unknown and unacceptable risks for mission success and post-mission crew health. This Integrated Research Plan (IRP) describes HRP s approach and research activities that are intended to address the needs of human space exploration and serve HRP customers and how they are integrated to provide a risk mitigation tool. The scope of the IRP is limited to the activities that can be conducted with the resources available to the HRP; it does not contain activities that would be performed if additional resources were available. The timescale of human space exploration is envisioned to take many decades. The IRP illustrates the program s research plan through the timescale of early lunar missions of extended duration.

  12. 2000 NASA-HU American Society for Engineering Education (ASEE) Summer Faculty Fellowship Program

    Science.gov (United States)

    Marable, William P. (Compiler); Murray, Deborah B. (Compiler); Hathaway, Roger A. (Technical Monitor)

    2000-01-01

    Since 1964, the National Aeronautics and Space Administration (NASA) has supported a program of summer faculty fellowships for engineering and science educators. In a series of collaborations between NASA research and development centers and nearby universities, engineering faculty members spend ten weeks working with professional peers on research. The Summer Faculty Program Committee of the American Society for Engineering Education supervises the programs. The objectives are: (1) to further the professional knowledge of qualified engineering and science faculty members; (2) to stimulate and exchange ideas between participants and NASA; (3) to enrich and refresh the research and teaching activities of participants' institutions; and (4) to contribute to the research objectives of the NASA center. College or university faculty members will be appointed as Research Fellows to spend ten weeks in cooperative research and study at the NASA Langley Research Center. The Fellow will devote approximately 90 percent of the time to a research problem and the remaining time to a study program. The study program will consist of lectures and seminars on topics of interest or that are directly relevant to the Fellows' research topics. The lecture and seminar leaders will be distinguished scientists and engineers from NASA, education, and industry. A list of the abstracts of the presentations is provided.

  13. Human Engineering Design Criteria for Modern Control/Display Components and Standard Parts.

    Science.gov (United States)

    1980-05-01

    Journal of Ergonomics and the Human Factors Journal indexes were reviewed. DDC and NASA STIF data bases were also searched. Human engineers specializing...addition, the Journal of Ergonomics and the Human Factors Journal indexes were reviewed. DDC and NASA STIF data bases were also searched. Human

  14. NASA information sciences and human factors program

    Science.gov (United States)

    Holcomb, Lee; Hood, Ray; Montemerlo, Melvin; Jenkins, James; Smith, Paul; Dibattista, John; Depaula, Ramon; Hunter, Paul; Lavery, David

    1991-01-01

    The FY-90 descriptions of technical accomplishments are contained in seven sections: Automation and Robotics, Communications, Computer Sciences, Controls and Guidance, Data Systems, Human Factors, and Sensor Technology.

  15. Human fetal bone cells in delivery systems for bone engineering.

    Science.gov (United States)

    Tenorio, Diene M H; Scaletta, Corinne; Jaccoud, Sandra; Hirt-Burri, Nathalie; Pioletti, Dominique P; Jaques, Bertrand; Applegate, Lee Ann

    2011-11-01

    The aim of this study was to culture human fetal bone cells (dedicated cell banks of fetal bone derived from 14 week gestation femurs) within both hyaluronic acid gel and collagen foam, to compare the biocompatibility of both matrices as potential delivery systems for bone engineering and particularly for oral application. Fetal bone cell banks were prepared from one organ donation and cells were cultured for up to 4 weeks within hyaluronic acid (Mesolis®) and collagen foams (TissueFleece®). Cell survival and differentiation were assessed by cell proliferation assays and histology of frozen sections stained with Giemsa, von Kossa and ALP at 1, 2 and 4 weeks of culture. Within both materials, fetal bone cells could proliferate in three-dimensional structure at ∼70% capacity compared to monolayer culture. In addition, these cells were positive for ALP and von Kossa staining, indicating cellular differentiation and matrix production. Collagen foam provides a better structure for fetal bone cell delivery if cavity filling is necessary and hydrogels would permit an injectable technique for difficult to treat areas. In all, there was high biocompatibility, cellular differentiation and matrix deposition seen in both matrices by fetal bone cells, allowing for easy cell delivery for bone stimulation in vivo. Copyright © 2011 John Wiley & Sons, Ltd.

  16. Emeritus Scientists, Mathematicians and Engineers (ESME) program. Summary of activities for school year 1991--1992

    Energy Technology Data Exchange (ETDEWEB)

    Sharlin, H.I.

    1992-09-01

    The Emeritus Scientists, Mathematicians and Engineers (ESME) program matches retired scientists and engineers with wide experience with elementary school children in order to fuel the children`s natural curiosity about the world in which they live. The long-range goal is to encourage students to maintain the high level of mathematical and science capability that they exhibit at an early age by introducing them to the fun and excitement of the world of scientific investigation and engineering problem solving. Components of the ESME program are the emeriti, established teacher-emeriti teams that work to produce a unit of 6 class hours of demonstration or hands-on experiments, and the encounter by students with the world of science/engineering through the classroom sessions and a field trip to a nearby plant or laboratory.

  17. Advanced Diesel Engine Component Development Program, final report - tasks 4-14

    Energy Technology Data Exchange (ETDEWEB)

    Kaushal, T.S.; Weber, K.E.

    1994-11-01

    The Advanced Diesel Engine Component Development (ADECD) Program is a multi-year, multi-phase effort to develop and demonstrate the critical technology needed to advance the heavy-duty low heat rejection (LHR) engine concept for the long-haul, heavy-duty truck market. The ADECD Program has been partitioned into two phases. The first phase, Phase 1, was completed in 1986, resulting in definition of the Advanced Diesel Reference Engine (ADRE)III. The second phase, Phase 11/111, examines the feasibility of the ADRE concepts for application to the on-highway diesel engine. Phase 11/111 is currently underway. This project is sponsored by the U.S. Department of Energy, Office of Transportation Technologies. The work has been performed by the Detroit Diesel Corporation (DDC) under Contract DEN3-329 with the NASA Lewis Research Center, who provide project management and technical direction.

  18. Summer Research Program (1992). High School Apprenticeship Program (HSAP) Reports. Volume 16. Arnold Engineering Development Center Civil Engineering Laboratory

    Science.gov (United States)

    1992-12-28

    you again next year. 10-13 CIVIL ENGINEERING LABORATORY A STUDY OF LITTORINA IRRORATA AND ITS ENVIRONMENT Philip C. Dorsch Student Lab Assistant Bay...Research was done on Littorina irrorata to see how they would react to a change In their envmroment. :.ites were selected in ýhe upper inmertldal zone...results from both the natural and artificial environments were compared and !ittlie chanrie was found. 11-2 A STUDY OF LITTORINA IRRORATA AND ITS

  19. NASA/American Society for Engineering Education (ASEE) Summer Faculty Fellowship Program 1987

    Science.gov (United States)

    Tiwari, Surendra N. (Compiler)

    1987-01-01

    Since 1964, NASA has supported a program of summer faculty fellowships for engineering and science educators. In a series of collaborations between NASA research and development centers and nearby universities, engineering faculty members spend 10 or 11 weeks working with professional peers on research. The Summer Faculty Program Committee of the American Society for Engineering Education supervises the programs. Objectives: (1) to further the professional knowledge of qualified engineering and science faculty members; (2) to stimulate and exchange ideas between participants and NASA; (3) to enrich and refresh the research and teaching activities of participants' institutions; (4) to contribute to the research objectives of the NASA center. Program Description: College or university faculty members were appointed as Research Fellows to spend 10 weeks in cooperative research and study at the NASA Langley Research Center. The Fellow devoted approximately 90 percent of the time to a research problem and the remaining time to a study program. The study program consisted of lectures and seminars on topics of interest or that are directly relevant to the Fellows' research topic.

  20. Manning and Maintainability of a Submarine Unmanned Undersea Vehicle (UUV) Program: A Systems Engineering Case Study

    Science.gov (United States)

    2010-09-01

    Program Executive Office Littoral and Mine Warfare PLM Product Lifecycle Management PSU ARL Pennsylvania State University Applied Research...such as this gives the Navy the ability to reach deep seas (up to 10,000 feet) in a reliable, covert fashion . In order to be successful for USN...of systems engineering. The future solution comes in the form of model-based systems engineering (MBSE) and product lifecycle management ( PLM

  1. Women in Engineering Program Advocates Network (WEPAN): Evaluation of the seventh annual conference

    Energy Technology Data Exchange (ETDEWEB)

    Brainard, S.G.

    1996-08-01

    The primary goals of the 1996 WEPAN Conference were to: (1) Conduct technical and programmatic seminars for institutions desiring to initiate, replicate, or expand women in engineering programs; (2) Provide assistance in fundraising and grant writing; (3) Profile women in engineering programs of excellence; (4) Sponsor inspiring, knowledgeable and motivational keynote speakers; and, (5) Offer a series of workshops focused on topics such as: establishing partnerships with industry, current research findings, retention strategies, issues affecting special populations, and early intervention techniques. In an effort to provide greater access for women to engineering careers, women in engineering program directors at Purdue University, Stevens Institute of Technology and the University of Washington joined together in 1990 to establish WEPAN, a national network of individuals interested in the recruitment, admission, retention, and graduation of women engineering students. This is the seventh year of operation. Success of this effort has been reflected in numerous ways: increased membership in the organization; increased number of women in engineering programs; increased number of women graduating in engineering; and grants from the U.S. Department of Energy, the National Science Foundation, the Alfred P. Sloan Foundation, the AT&T Foundation, and many other corporations to carry out the goals of WEPAN. The Seventh Annual Women in Engineering Conference entitled, Capitalizing on Today`s Challenges, was held in Denver, Colorado on June 1-4, 1996 at the Hyatt Regency. The conference brought together representatives from academia, government, and industry and examined current issues and initiatives for women in technology, science, and education. Building on the successes of the previous conferences, the seventh conference offered a new variety of speakers and topics.

  2. Assessing and mitigating risks of engineering programs with lean management techniques

    DEFF Research Database (Denmark)

    Fritz, A.; Oehmen, Josef; Rebentisch, E.

    2014-01-01

    This paper investigates the use of lean management techniques as a risk mitigation approach for large-scale engineering programs. The key research questions are how lean best practices with the highest risk mitigation potential are identified, how the most relevant lean best practices for a speci......This paper investigates the use of lean management techniques as a risk mitigation approach for large-scale engineering programs. The key research questions are how lean best practices with the highest risk mitigation potential are identified, how the most relevant lean best practices...... for a specific program are identified and how the effort for implementation of these lean best practices is estimated. Large-scale engineering programs have as results usually complex technical products or systems such as airplanes, satellites (GPS) or software programs, immense infrastructure efforts like...... [Shao and Müller 2011, Shao et al. 2012]. To incorporate these capabilities and to manage the obviously difficult entity of a program, a variety of standards and guidance books have been published. The two most prominent ones are Managing Successful Programs (MSP) and The Standard for Program Management...

  3. Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery.

    Science.gov (United States)

    Lin, Steven; Staahl, Brett T; Alla, Ravi K; Doudna, Jennifer A

    2014-12-15

    The CRISPR/Cas9 system is a robust genome editing technology that works in human cells, animals and plants based on the RNA-programmed DNA cleaving activity of the Cas9 enzyme. Building on previous work (Jinek et al., 2013), we show here that new genetic information can be introduced site-specifically and with high efficiency by homology-directed repair (HDR) of Cas9-induced site-specific double-strand DNA breaks using timed delivery of Cas9-guide RNA ribonucleoprotein (RNP) complexes. Cas9 RNP-mediated HDR in HEK293T, human primary neonatal fibroblast and human embryonic stem cells was increased dramatically relative to experiments in unsynchronized cells, with rates of HDR up to 38% observed in HEK293T cells. Sequencing of on- and potential off-target sites showed that editing occurred with high fidelity, while cell mortality was minimized. This approach provides a simple and highly effective strategy for enhancing site-specific genome engineering in both transformed and primary human cells.

  4. Enhancement of the Work in Scia Engineer's Environment by Employment of XML Programming Language

    Directory of Open Access Journals (Sweden)

    Kortiš Ján

    2015-12-01

    Full Text Available The productivity of the work of engineers in the design of building structures by applying the rules of technical standards [1] has been increasing by using different software products for recent years. The software products offer engineers new possibilities to design different structures. However, there are problems especially for design of structures with similar static schemes as it is needed to follow the same work-steps. This can be more effective if the steps are done automatically by using a programming language for leading the processes that are done by software. The design process of timber structure which is done in the environment of Scia Engineer software is presented in the article. XML Programming Language is used for automatization of the design and the XML code is modified in the Excel environment by using VBA Programming language [2], [3].

  5. The MetSkill Program — Rapidly Developing Effective Young Engineers in the Workplace

    Science.gov (United States)

    Drinkwater, Diana; Bianco, Nina

    MetSkill is a professional development program for metallurgical engineers that integrates with normal duties in their first one or two years of service. Graduates work together on a structured technical project, facilitated by specialists and supported by formal learning, and ultimately reported to their technical managers. The program enables graduates to "fill the gaps" in their undergraduate education, which is increasingly pertinent as engineering degrees become more general. Participants report that they enjoy the focus on more challenging (rewarding) aspects of their jobs and feel more confident about problem solving. Sponsor companies add that the relationships developed with external technical specialists enhances opportunities for innovation and development. MetSkill was delivered to two major resource companies in Australia in 2012. This paper provides an outline of the program and the reasons for its success, and demonstrates how the learning model could be applied to groups of graduates in other engineering disciplines.

  6. KONFIG and REKONFIG: Two interactive preprocessing to the Navy/NASA Engine Program (NNEP)

    Science.gov (United States)

    Fishbach, L. H.

    1981-01-01

    The NNEP is a computer program that is currently being used to simulate the thermodynamic cycle performance of almost all types of turbine engines by many government, industry, and university personnel. The NNEP uses arrays of input data to set up the engine simulation and component matching method as well as to describe the characteristics of the components. A preprocessing program (KONFIG) is described in which the user at a terminal on a time shared computer can interactively prepare the arrays of data required. It is intended to make it easier for the occasional or new user to operate NNEP. Another preprocessing program (REKONFIG) in which the user can modify the component specifications of a previously configured NNEP dataset is also described. It is intended to aid in preparing data for parametric studies and/or studies of similar engines such a mixed flow turbofans, turboshafts, etc.

  7. Enhancement of the Work in Scia Engineer's Environment by Employment of XML Programming Language

    Science.gov (United States)

    Kortiš, Ján

    2015-12-01

    The productivity of the work of engineers in the design of building structures by applying the rules of technical standards [1] has been increasing by using different software products for recent years. The software products offer engineers new possibilities to design different structures. However, there are problems especially for design of structures with similar static schemes as it is needed to follow the same work-steps. This can be more effective if the steps are done automatically by using a programming language for leading the processes that are done by software. The design process of timber structure which is done in the environment of Scia Engineer software is presented in the article. XML Programming Language is used for automatization of the design and the XML code is modified in the Excel environment by using VBA Programming language [2], [3].

  8. IMpact of international accreditation in the recognition of academic degrees in the domestic and foreign labor market. Case study: Civil engineering program

    Directory of Open Access Journals (Sweden)

    Jose Barragan Codina

    2015-07-01

    Full Text Available In a globalized era it is not enough to have a professional qualification to ensure economic and professional success. The academic background of professionals must be adequate to face challenges and solve problems of a globalized and dynamic world. Civil engineers face many complications when seeking an international career. There are many differences within the profession globally such as: resources, workforce, climate, language, culture, philosophies, regulations, etc. which raise the entry barriers to fully practice as a civil engineer. The International accreditations play a major role as the first evidence of the civil engineer technical proficiency. These assure the quality of the higher education curricula and add value to the human capital on an international context. Despite the fact that many Mexican Universities have academic programs which have international accreditations, civil engineer graduates cannot easily work across borders. This paper describes the impact that international accreditation has for civil engineers when seeking an international career.

  9. ESPACE - a geodetic Master's program for the education of Satellite Application Engineers

    Science.gov (United States)

    Hedman, K.; Kirschner, S.; Seitz, F.

    2012-04-01

    In the last decades there has been a rapid development of new geodetic and other Earth observation satellites. Applications of these satellites such as car navigation systems, weather predictions, and, digital maps (such as Google Earth or Google Maps) play a more and more important role in our daily life. For geosciences, satellite applications such as remote sensing and precise positioning/navigation have turned out to be extremely useful and are meanwhile indispensable. Today, researchers within geodesy, climatology, oceanography, meteorology as well as within Earth system science are all dependent on up-to-date satellite data. Design, development and handling of these missions require experts with knowledge not only in space engineering, but also in the specific applications. That gives rise to a new kind of engineers - satellite application engineers. The study program for these engineers combines parts of different classical disciplines such as geodesy, aerospace engineering or electronic engineering. The satellite application engineering program Earth Oriented Space Science and Technology (ESPACE) was founded in 2005 at the Technische Universität München, mainly from institutions involved in geodesy and aerospace engineering. It is an international, interdisciplinary Master's program, and is open to students with a BSc in both Science (e.g. Geodesy, Mathematics, Informatics, Geophysics) and Engineering (e.g. Aerospace, Electronical and Mechanical Engineering). The program is completely conducted in English. ESPACE benefits from and utilizes its location in Munich with its unique concentration of expertise related to space science and technology. Teaching staff from 3 universities (Technische Universität München, Ludwig-Maximilian University, University of the Federal Armed Forces), research institutions (such as the German Aerospace Center, DLR and the German Geodetic Research Institute, DGFI) and space industry (such as EADS or Kayser-Threde) are

  10. INCREASING ACHIEVEMENT AND HIGHER-EDUCATION REPRESENTATION OF UNDER-REPRESENTED GROUPS IN SCIENCE, TECHNOLOGY, ENGINEERING, AND MATHEMATICS FIELDS: A REVIEW OF CURRENT K-12 INTERVENTION PROGRAMS.

    Science.gov (United States)

    Valla, Jeffrey M; Williams, Wendy M

    2012-01-01

    The under-representation of women and ethnic minorities in Science, Technology, Engineering, and Mathematics (STEM) education and professions has resulted in a loss of human capital for the US scientific workforce and spurred the development of myriad STEM educational intervention programs. Increased allocation of resources to such programs begs for a critical, prescriptive, evidence-based review that will enable researchers to develop optimal interventions and administrators to maximize investments. We begin by providing a theoretical backdrop for K-12 STEM programs by reviewing current data on under-representation and developmental research describing individual-level social factors undergirding these data. Next, we review prototypical designs of these programs, highlighting specific programs in the literature as examples of program structures and components currently in use. We then evaluate these interventions in terms of overall effectiveness, as a function of how well they address age-, ethnicity-, or gender-specific factors, suggesting improvements in program design based on these critiques. Finally, program evaluation methods are briefly reviewed and discussed in terms of how their empirical soundness can either enable or limit our ability to delineate effective program components. "Now more than ever, the nation's changing demographics demand that we include all of our citizens in science and engineering education and careers. For the U.S. to benefit from the diverse talents of all its citizens, we must grow the pipeline of qualified, underrepresented minority engineers and scientists to fill positions in industry and academia."-Irving P. McPhail..

  11. Hydrocarbon emissions from gas engine CHP-units. 2011 measurement program

    Energy Technology Data Exchange (ETDEWEB)

    Van Dijk, G.H.J. [KEMA, Arnhem (Netherlands)

    2012-06-15

    In December 2009, the Ministry of Infrastructure and Environment (IandM) issued the Decree on Emission Limits for Middle Sized Combustion Installations (BEMS). This decree imposes a first-time emission limit value (ELV) of 1500 mg C/m{sup 3}{sub o} at 3% O{sub 2} for hydrocarbons emitted by gas engines. IandM used the findings of two hydrocarbon emission measurement programs, executed in 2007 and 2009, as a guideline for this initial ELV. The programs did reveal substantial variation in the hydrocarbon emissions of the gas engines tested. This variation, and especially the uncertainty as to the role of engine and/or other parameters causing such variation, was felt to hamper further policy development. IandM therefore commissioned KEMA to perform follow-up measurements on ten gas engine CHP-units in 2011. Aim of this 2011 program is to assess hydrocarbon emission variation in relation to engine parameters and process conditions including maintenance status, and to atmospheric conditions. The 2011 program comprised two identical measurement sessions, one in spring and one in winter.

  12. Implementation analysis of lean enablers for managing engineering programs

    DEFF Research Database (Denmark)

    von Arnim, Joachim; Oehmen, Josef; Rebentisch, Eric

    2014-01-01

    This paper presents research to improve the applicability of the Lean Enablers and consists of two parts. The first is a case study of a very successful project management maturity improvement initiative at Siemens Industry Sector’s Industry Automation division in the US. It views the initiative...... from the perspective of the Lean Enablers [Oehmen 2012] and is based on information from [Sopko 2012a], [Sopko 2012b], [Sopko 2010], [Sopko 2009], interviews, internal documentation, and the used MSP program management methodology [UK 2011]. The analysis of Lean Enablers incorporated in the MSP...... framework reveals the potential of Lean Enablers being applied in change programs. Incorporating the knowledge gained in the case study, the second part shows the development of a framework for the implementation of Lean Enablers....

  13. Sustaining liminality: Experiences and negotiations of international females in U.S. engineering graduate programs

    Science.gov (United States)

    Dutta, Debalina

    This project examines the intersectionalities of international females in engineering graduate programs of the United States, using frameworks of sustainability and liminality theory. According to Dutta and Kisselburgh (2011) international females in graduate engineering constitute the minorities of minorities, not only in terms of their status as international students but also by their underrepresentation as women in engineering (Faulkner, 2009). Research regarding international female graduate students tends to be categorized as the experiences of international students in the U.S. (Lee & Rice, 2007), or as the struggles of female engineers in engineering disciplines (Tonso, 2007). Therefore, this project aims to distinguish the unique population of female engineers of international origin from holistic studies of international students, and attempts to draw out and understand the experiences of international female students in U.S. engineering graduate programs. Dutta and Kisselburgh (2011) found that female engineers who are international in origin exist in liminal states indefinitely. This liminal nature has been described under the theory of liminality (Turner, 1967) which posits that when transitioning from one life-changing event to another (such as birth, death, marriage), individuals go through a transformatory phase where they are subjected to invisibility, vulnerability, and a feeling of loss. Although Turner posited this phase as transcendental and temporary, Dutta and Kisselburgh (2011) suggest the liminal period can be more permanent in contemporary global societies. In other words, liminal experiences of vulnerability and structural invisibility may be sustained experiences of international female engineering students. Furthermore, the project attends to the overlaps, tensions and challenging experiences faced by international females in surviving engineering graduate program. To achieve this goal, liminality theory is limited in accounting for how

  14. Geothermal reservoir engineering management program plan (GREMP Plan)

    Energy Technology Data Exchange (ETDEWEB)

    1977-10-01

    A plan was formulated for development of the geothermal resources of the United States. Six major elements were identified to make up the research program structure. These are: properties of materials; definition of reservoir characteristics; description of example reservoirs; modeling the behavior of geothermal systems; exploitation strategies; and economics. The six elements yield twelve research categories and fifty research projects. These are discussed in detail in Appendix A and summarized in a table. (JGB)

  15. Automated discovery of functional generality of human gene expression programs.

    Directory of Open Access Journals (Sweden)

    Georg K Gerber

    2007-08-01

    Full Text Available An important research problem in computational biology is the identification of expression programs, sets of co-expressed genes orchestrating normal or pathological processes, and the characterization of the functional breadth of these programs. The use of human expression data compendia for discovery of such programs presents several challenges including cellular inhomogeneity within samples, genetic and environmental variation across samples, uncertainty in the numbers of programs and sample populations, and temporal behavior. We developed GeneProgram, a new unsupervised computational framework based on Hierarchical Dirichlet Processes that addresses each of the above challenges. GeneProgram uses expression data to simultaneously organize tissues into groups and genes into overlapping programs with consistent temporal behavior, to produce maps of expression programs, which are sorted by generality scores that exploit the automatically learned groupings. Using synthetic and real gene expression data, we showed that GeneProgram outperformed several popular expression analysis methods. We applied GeneProgram to a compendium of 62 short time-series gene expression datasets exploring the responses of human cells to infectious agents and immune-modulating molecules. GeneProgram produced a map of 104 expression programs, a substantial number of which were significantly enriched for genes involved in key signaling pathways and/or bound by NF-kappaB transcription factors in genome-wide experiments. Further, GeneProgram discovered expression programs that appear to implicate surprising signaling pathways or receptor types in the response to infection, including Wnt signaling and neurotransmitter receptors. We believe the discovered map of expression programs involved in the response to infection will be useful for guiding future biological experiments; genes from programs with low generality scores might serve as new drug targets that exhibit minimal

  16. A 4-cylinder Stirling engine computer program with dynamic energy equations

    Science.gov (United States)

    Daniele, C. J.; Lorenzo, C. F.

    1983-05-01

    A computer program for simulating the steady state and transient performance of a four cylinder Stirling engine is presented. The thermodynamic model includes both continuity and energy equations and linear momentum terms (flow resistance). Each working space between the pistons is broken into seven control volumes. Drive dynamics and vehicle load effects are included. The model contains 70 state variables. Also included in the model are piston rod seal leakage effects. The computer program includes a model of a hydrogen supply system, from which hydrogen may be added to the system to accelerate the engine. Flow charts are provided.

  17. DB90: A Fortran Callable Relational Database Routine for Scientific and Engineering Computer Programs

    Science.gov (United States)

    Wrenn, Gregory A.

    2005-01-01

    This report describes a database routine called DB90 which is intended for use with scientific and engineering computer programs. The software is written in the Fortran 90/95 programming language standard with file input and output routines written in the C programming language. These routines should be completely portable to any computing platform and operating system that has Fortran 90/95 and C compilers. DB90 allows a program to supply relation names and up to 5 integer key values to uniquely identify each record of each relation. This permits the user to select records or retrieve data in any desired order.

  18. PERAN PROGRAM STUDI TEKNIK PANGAN (FOOD ENGINEERING UNTUK MENUNJANG PEMBANGUNAN INDUSTRI PANGAN DI INDONESIA [The Roles of Engineering fot the Development of Agro Industries in Indonesia

    Directory of Open Access Journals (Sweden)

    Suhargo

    2005-08-01

    Full Text Available At this time more than 60 % of Indonesian population still depend on the agricultural sector. Accordingly, in future agro and food industries are expected to be the main steppingstone for the economic development in Indonesia. In order to make the agricultural products competitive in the global market; it is necessary that the development of food or agro industries is supported by technology especially in the food product development and their processing. The food product development consist of food product design, process design, equipment and machinery design and packaging design. Consequently the food product development requires the knowledge of food science, and is necessary to be supported by the knowledge of engineering or know as food engineering. As a course, food engineering is already offered in the study program of food science and technology. However, food engineering is not developed yet as a study program as well as in the other countries, the study program in food engineering is necessarily different from the study program of food science and technology. Food engineering is scientific discipline to study and apply the engineering principles in food preservation, conservation, conversion and distribution. In several countries both study programs are paralely offered as two different study programs with deferent competence and knowledge. The competency of food engineering is mainly in the application of engineering knowledge for food design, design and construction of food process equipment, process design, process equipment operation and management. Accordingly, the content of the food engineering curriculum covers engineering and physics (50-60%, biology and food science (20-30% and other supporting knowledge’s (statics, communication, etc, 10-20%. The graduates in food engineering will have opportunities working as engineers as well as designing, constructing and operating process equipment in food industries

  19. Human resource management engineering companies Ukraine under crisis

    Directory of Open Access Journals (Sweden)

    Redkva, Oksana Zinoviyivna

    2011-11-01

    Full Text Available The features of personal management at engineering enterprises in the crisis are describes and discuses in the article. The problems and causes of inefficient personnel management are identified. Jome recommendations concerming solving of problem in the sphere of personal management and effective management of engineering enterprises are giver.

  20. Unifying Human Centered Design and Systems Engineering for Human Systems Integration

    Science.gov (United States)

    Boy, Guy A.; McGovernNarkevicius, Jennifer

    2013-01-01

    Despite the holistic approach of systems engineering (SE), systems still fail, and sometimes spectacularly. Requirements, solutions and the world constantly evolve and are very difficult to keep current. SE requires more flexibility and new approaches to SE have to be developed to include creativity as an integral part and where the functions of people and technology are appropriately allocated within our highly interconnected complex organizations. Instead of disregarding complexity because it is too difficult to handle, we should take advantage of it, discovering behavioral attractors and the emerging properties that it generates. Human-centered design (HCD) provides the creativity factor that SE lacks. It promotes modeling and simulation from the early stages of design and throughout the life cycle of a product. Unifying HCD and SE will shape appropriate human-systems integration (HSI) and produce successful systems.

  1. The impact of program experiences on the retention of women engineering students in Mexico

    Science.gov (United States)

    Villa, Maria Del Carmen Garcia

    This qualitative study sought to describe and understand the experiences of female students attending engineering colleges in Mexico and the sources of support and strategies that helped them persist in their programs. The participants were 20 women engineering students enrolled in at least their third year in selected colleges of engineering in Mexico, in both public and private universities, and pursuing a variety of engineering majors. Findings focus on the experiences of female students that helped them stay in their programs. Participants described their experiences in college as very challenging and perceived the environment as hostile and uncertain. In addition, patriarchal Mexican cultural values and stereotypes were identified by students as influencing and helping shape the engineering environment. However, in this context, participants were able to find sources of support and use strategies that helped them remain in their majors, such as a strong desire to succeed, a perceived academic self-ability; and support from their families, peers, institutions, and---most importantly---their professors. Furthermore, the fact that participants were able to persist in their programs gave them a sense of pride and satisfaction that was shared by their families, peers, and faculty. In addition, participants experienced contradictory forces and were constantly negotiating between rejecting traditional gender norms and upholding the norms that are so deeply engrained in Mexican society. Finally, as the students advanced in their programs and became "accepted to the club," they tended to reproduce the male-dominated value system present in engineering colleges accepting their professors' expectations of being "top students," accepting the elitist culture of engineering superiority, and embracing the protection given by their male peers. Retention of Mexican female engineering students is important for all engineering colleges, but cultural factors must be taken into

  2. Cartilage tissue engineering using pre-aggregated human articular chondrocytes

    Directory of Open Access Journals (Sweden)

    F Wolf

    2008-12-01

    Full Text Available In this study, we first aimed at determining whether human articular chondrocytes (HAC proliferate in aggregates in the presence of strong chondrocyte mitogens. We then investigated if the aggregated cells have an enhanced chondrogenic capacity as compared to cells cultured in monolayer. HAC from four donors were cultured in tissue culture dishes either untreated or coated with 1% agarose in the presence of TGFb-1, FGF-2 and PDGF-BB. Proliferation and stage of differentiation were assessed by measuring respectively DNA contents and type II collagen mRNA. Expanded cells were induced to differentiate in pellets or in Hyaff®-11 meshes and the formed tissues were analysed biochemically for glycosaminoglycans (GAG and DNA, and histologically by Safranin O staining. The amount of DNA in aggregate cultures increased significantly from day 2 to day 6 (by 3.2-fold, but did not further increase with additional culture time. Expression of type II collagen mRNA was about two orders of magnitude higher in aggregated HAC as compared to monolayer expanded cells. Pellets generated by aggregated HAC were generally more intensely stained for GAG than those generated by monolayer-expanded cells. Scaffolds seeded with aggregates accumulated more GAG (1.3-fold than scaffolds seeded with monolayer expanded HAC. In conclusion, this study showed that HAC culture in aggregates does not support a relevant degree of expansion. However, aggregation of expanded HAC prior to loading into a porous scaffold enhances the quality of the resulting tissues and could thus be introduced as an intermediate culture phase in the manufacture of engineered cartilage grafts.

  3. DOE Human Genome Program contractor-grantee workshop

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-01-01

    This volume contains the proceedings for the DOE Human Genome Program`s Contractor-Grantee Workshop V held in Sante Fe, New Mexico January 28, February 1, 1996. Presentations were divided into sessions entitled Sequencing; Mapping; Informatics; Ethical, Legal, and Social Issues; and Infrastructure. Reports of individual projects described herein are separately indexed and abstracted for the database.

  4. Human Genome Program Report. Part 1, Overview and Progress

    Science.gov (United States)

    1997-11-01

    This report contains Part 1 of a two-part report to reflect research and progress in the U.S. Department of Energy Human Genome Program from 1994 through 1996, with specified updates made just before publication. Part 1 consists of the program overview and report on progress.

  5. Human genome program report. Part 1, overview and progress

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-11-01

    This report contains Part 1 of a two-part report to reflect research and progress in the U.S. Department of Energy Human Genome Program from 1994 through 1996, with specified updates made just before publication. Part 1 consists of the program overview and report on progress.

  6. Implementation analysis of lean enablers for managing engineering programs

    DEFF Research Database (Denmark)

    von Arnim, Joachim; Oehmen, Josef; Rebentisch, Eric

    2014-01-01

    from the perspective of the Lean Enablers [Oehmen 2012] and is based on information from [Sopko 2012a], [Sopko 2012b], [Sopko 2010], [Sopko 2009], interviews, internal documentation, and the used MSP program management methodology [UK 2011]. The analysis of Lean Enablers incorporated in the MSP......This paper presents research to improve the applicability of the Lean Enablers and consists of two parts. The first is a case study of a very successful project management maturity improvement initiative at Siemens Industry Sector’s Industry Automation division in the US. It views the initiative...

  7. Near Earth Asteroid Solar Sail Engineering Development Unit Test Program

    Science.gov (United States)

    Lockett, Tiffany Russell; Few, Alexander; Wilson, Richard

    2017-01-01

    The Near Earth Asteroid (NEA) Scout project is a 30x20x10cm (6U) cubesat reconnaissance mission to investigate a near Earth asteroid utilizing an 86m2 solar sail as the primary propulsion system. This will be the largest solar sail NASA will launch to date. NEA Scout is a secondary payload currently manifested on the maiden voyage of the Space Launch System in 2018. In development of the solar sail subsystem, design challenges were identified and investigated for packaging within a 6U form factor and deployment in cis-lunar space. Analysis furthered understanding of thermal, stress, and dynamics of the stowed system and matured an integrated sail membrane model for deployed flight dynamics. This paper will address design, fabrication, and lessons learned from the NEA Scout solar sail subsystem engineering development unit. From optical properties of the sail material to folding and spooling the single 86m2 sail, the team has developed a robust deployment system for the solar sail. This paper will also address expected and received test results from ascent vent, random vibration, and deployment tests.

  8. Concept document of the repository-based software engineering program: A constructive appraisal

    Science.gov (United States)

    1992-01-01

    A constructive appraisal of the Concept Document of the Repository-Based Software Engineering Program is provided. The Concept Document is designed to provide an overview of the Repository-Based Software Engineering (RBSE) Program. The Document should be brief and provide the context for reading subsequent requirements and product specifications. That is, all requirements to be developed should be traceable to the Concept Document. Applied Expertise's analysis of the Document was directed toward assuring that: (1) the Executive Summary provides a clear, concise, and comprehensive overview of the Concept (rewrite as necessary); (2) the sections of the Document make best use of the NASA 'Data Item Description' for concept documents; (3) the information contained in the Document provides a foundation for subsequent requirements; and (4) the document adequately: identifies the problem being addressed; articulates RBSE's specific role; specifies the unique aspects of the program; and identifies the nature and extent of the program's users.

  9. Assessment of factors impacting success for incoming college engineering students in a summer bridge program

    Science.gov (United States)

    Reisel, John R.; Jablonski, Marissa; Hosseini, Hossein; Munson, Ethan

    2012-06-01

    A summer bridge program for incoming engineering and computer science freshmen has been used at the University of Wisconsin-Milwaukee from 2007 to 2010. The primary purpose of this program has been to improve the mathematics course placement for incoming students who initially place into a course below Calculus I on the math placement examination. The students retake the university's math placement examination after completing the bridge program to determine if they then place into a higher-level mathematics course. If the students improve their math placement, the program is considered successful for that student. The math portion of the bridge program is designed around using the ALEKS software package for targeted, self-guided learning. In the 2007 and 2008 versions of the program, both an on-line version and an on-campus version with additional instruction were offered. In 2009 and 2010, the program was exclusively in an on-campus format, and also featured a required residential component and additional engineering activities for the students. From the results of these four programs, we are able to evaluate the success of the program in its different formats. In addition, data has been collected and analysed regarding the impact of other factors on the program's success. The factors include student preparation before the beginning of the program (as measured by math ACT scores) and the amount of time the student spent working on the material during the program. Better math preparation and the amount of time spent on the program were found to be good indicators of success. Furthermore, the on-campus version of the program is more effective than the on-line version.

  10. Social Engineering: I-E based Model of Human Weakness for Attack and Defense Investigations

    Directory of Open Access Journals (Sweden)

    Wenjun Fan

    2017-01-01

    Full Text Available Social engineering is the attack aimed to manipulate dupe to divulge sensitive information or take actions to help the adversary bypass the secure perimeter in front of the information-related resources so that the attacking goals can be completed. Though there are a number of security tools, such as firewalls and intrusion detection systems which are used to protect machines from being attacked, widely accepted mechanism to prevent dupe from fraud is lacking. However, the human element is often the weakest link of an information security chain, especially, in a human-centered environment. In this paper, we reveal that the human psychological weaknesses result in the main vulnerabilities that can be exploited by social engineering attacks. Also, we capture two essential levels, internal characteristics of human nature and external circumstance influences, to explore the root cause of the human weaknesses. We unveil that the internal characteristics of human nature can be converted into weaknesses by external circumstance influences. So, we propose the I-E based model of human weakness for social engineering investigation. Based on this model, we analyzed the vulnerabilities exploited by different techniques of social engineering, and also, we conclude several defense approaches to fix the human weaknesses. This work can help the security researchers to gain insights into social engineering from a different perspective, and in particular, enhance the current and future research on social engineering defense mechanisms.

  11. Guest Editorial: Master of engineering program in biomedical engineering at Cornell University: Collaboration with external sponsors to prove concepts in assistive devices

    Directory of Open Access Journals (Sweden)

    David Lipson, PhD

    2010-12-01

    Full Text Available As a biomedical engineer, one seldom gets the opportunity to help patients return to health in areas in which the magnitude of the need, or the adoption of the approach, is unproven. Returning to my alma mater, Cornell University in Ithaca, New York, in late 2004, I was given the opportunity to coordinate the master of engineering program in biomedical engineering. Teaching students about the biomedical engineering arts and the Food and Drug Administration environment, and using projects proposed by external companies and physicians, we began to build a new Department of Biomedical Engineering.

  12. Conceptual framework for a Danish human biomonitoring program

    DEFF Research Database (Denmark)

    Thomsen, Marianne; Knudsen, Lisbeth; Vorkamp, Katrin

    2008-01-01

    The aim of this paper is to present the conceptual framework for a Danish human biomonitoring (HBM) program. The EU and national science-policy interface, that is fundamental for a realization of the national and European environment and human health strategies, is discussed, including the need...

  13. Values and Issues: The Humanities Program at Wofford College.

    Science.gov (United States)

    Thoroughman, Thomas V.

    1979-01-01

    The development of a new humanities program is described. This includes a freshman seminar as an introduction to humanistic study, the modification of traditional language requirements, and the establishment of a writing and reading lab, an issues and values interdisciplinary seminar, and humanities and intercultural majors. (Author/MLW)

  14. A CAL Program to Teach the Basic Principles of Genetic Engineering--A Change from the Traditional Approach.

    Science.gov (United States)

    Dewhurst, D. G.; And Others

    1989-01-01

    An interactive computer-assisted learning program written for the BBC microcomputer to teach the basic principles of genetic engineering is described. Discussed are the hardware requirements software, use of the program, and assessment. (Author/CW)

  15. A CAL Program to Teach the Basic Principles of Genetic Engineering--A Change from the Traditional Approach.

    Science.gov (United States)

    Dewhurst, D. G.; And Others

    1989-01-01

    An interactive computer-assisted learning program written for the BBC microcomputer to teach the basic principles of genetic engineering is described. Discussed are the hardware requirements software, use of the program, and assessment. (Author/CW)

  16. Minority Universities Systems Engineering (MUSE) Program at the University of Texas at El Paso

    Science.gov (United States)

    Robbins, Mary Clare; Usevitch, Bryan; Starks, Scott A.

    1997-01-01

    In 1995, The University of Texas at El Paso (UTEP) responded to the suggestion of NASA Jet Propulsion Laboratory (NASA JPL) to form a consortium comprised of California State University at Los Angeles (CSULA), North Carolina Agricultural and Technical University (NCAT), and UTEP from which developed the Minority Universities Systems Engineering (MUSE) Program. The mission of this consortium is to develop a unique position for minority universities in providing the nation's future system architects and engineers as well as enhance JPL's system design capability. The goals of this collaboration include the development of a system engineering curriculum which includes hands-on project engineering and design experiences. UTEP is in a unique position to take full advantage of this program since UTEP has been named a Model Institution for Excellence (MIE) by the National Science Foundation. The purpose of MIE is to produce leaders in Science, Math, and Engineering. Furthermore, UTEP has also been selected as the site for two new centers including the Pan American Center for Earth and Environmental Sciences (PACES) directed by Dr. Scott Starks and the FAST Center for Structural Integrity of Aerospace Systems directed by Dr. Roberto Osegueda. The UTEP MUSE Program operates under the auspices of the PACES Center.

  17. Integration of Wind Energy Systems into Power Engineering Education Program at UW-Madison

    Energy Technology Data Exchange (ETDEWEB)

    Venkataramanan, Giri [Univ. of Wisconsin, Madison, WI (United States); Lesieutre, Bernard [Univ. of Wisconsin, Madison, WI (United States); Jahns, Thomas [Univ. of Wisconsin, Madison, WI (United States); Desai, Ankur R [Univ. of Wisconsin, Madison, WI (United States)

    2012-09-01

    This project has developed an integrated curriculum focused on the power engineering aspects of wind energy systems that builds upon a well-established graduate educational program at UW- Madison. Five new courses have been developed and delivered to students. Some of the courses have been offered on multiple occasions. The courses include: Control of electric drives for Wind Power applications, Utility Applications of Power Electronics (Wind Power), Practicum in Small Wind Turbines, Utility Integration of Wind Power, and Wind and Weather for Scientists and Engineers. Utility Applications of Power Electronics (Wind Power) has been provided for distance education as well as on-campus education. Several industrial internships for students have been organized. Numerous campus seminars that provide discussion on emerging issues related to wind power development have been delivered in conjunction with other campus events. Annual student conferences have been initiated, that extend beyond wind power to include sustainable energy topics to draw a large group of stakeholders. Energy policy electives for engineering students have been identified for students to participate through a certificate program. Wind turbines build by students have been installed at a UW-Madison facility, as a test-bed. A Master of Engineering program in Sustainable Systems Engineering has been initiated that incorporates specializations that include in wind energy curricula. The project has enabled UW-Madison to establish leadership at graduate level higher education in the field of wind power integration with the electric grid.

  18. District cooling engineering & design program. Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    1994-03-01

    Phoenix, Arizona is located in the Sonoran desert. Daytime temperatures typically rise to over 100 F during the three summer months. Average and peak temperatures have tended to rise over recent decades. This is generally attributed to what is known as the heat island effect, due to an increase in heat absorbing concrete and a decrease in irrigated farmland in the area. Phoenix is the eighth largest city in the US with a population of just over one million (1,000,000). The metropolitan area is one of the fastest growing in the nation. Over the last ten years its population has increased by over 40%. It is not an exaggeration to say the general availability of refrigerated air conditioning, both for buildings and automobiles has been an important factor enabling growth. The cost of operating public buildings has risen significantly in the last decade. In fiscal year 92/93 the City of Phoenix had energy expenses of over thirty four million dollars ($34,000,000). Because the City was planning a major new construction project, a new high-rise City Hall, it was decided to study and then optimize the design and selection of building systems to minimize long term owning and operating costs. The City Hall was to be constructed in downtown Phoenix. Phoenix presently owns other buildings in the area. A number of large cooling systems serving groups of buildings are currently operating in the Phoenix area. The City requested that the design consultants analyze the available options and present recommendations to the City`s engineering staff.

  19. New dimensions in tissue engineering: possible models for human physiology.

    Science.gov (United States)

    Baar, Keith

    2005-11-01

    Tissue engineering is a discipline of great promise. In some areas, such as the cornea, tissues engineered in the laboratory are already in clinical use. In other areas, where the tissue architecture is more complex, there are a number of obstacles to manoeuvre before clinically relevant tissues can be produced. However, even in areas where clinically relevant tissues are decades away, the tissues being produced at the moment provide powerful new models to aid the understanding of complex physiological processes. This article provides a personal view of the role of tissue engineering in advancing our understanding of physiology, with specific attention being paid to musculoskeletal tissues.

  20. Environmental Barrier Coatings for the Energy Efficient Heat Engines Program

    Energy Technology Data Exchange (ETDEWEB)

    Katherine Faber

    2004-10-31

    This program aimed to develop a fundamental understanding of the microstructural, mechanical, and chemical properties of Ta{sub 2}O{sub 5}-based coatings for Si{sub 3}N{sub 4} (AS800) substrates and optimize such coatings for environmental barriers. The program consisted of three tasks: processing of Ta{sub 2}O{sub 5} coatings, phase and microstructural development, and life-limiting phenomena. Northwestern University formed a cross-functional team with Lehigh University, Honeywell Inc., and Oak Ridge National Laboratory. The major accomplishments are: (1) Conditions for the plasma spray of Ta{sub 2}O{sub 5} and its alloys were optimized to provide maximum density and thickness. (2) Adherent small particle plasma spray coatings of Ta{sub 2}O{sub 5} can be routinely prepared. (3) Ta{sub 2}O{sub 5} can be stabilized against its disruptive phase transformation to 1400 C by the addition of one or more oxides of Al, La, and/or Nb. (4) Residual stresses in the Ta{sub 2}O{sub 5} coatings were measured using X-rays and changed with thermal exposure. (5) Properly doped coatings are more resistant against thermal cycling than undoped coatings, and can be cycled many thousand times without spallation. (6) Water vapor testing in the ORNL Keiser Rig of adherent coatings showed that undoped Ta{sub 2}O{sub 5} is not an effective barrier at preventing chemical changes to the AS800. (7) Limited water vapor testing of doped and adherent coatings, which had successfully survived many thermal cycles, showed that in the water vapor environment, de-cohesion may occur.

  1. Stirling Space Engine Program. Volume 2; Appendixes A, B, C and D

    Science.gov (United States)

    Dhar, Manmohan

    1999-01-01

    The objective of this program was to develop the technology necessary for operating Stirling power converters in a space environment and to demonstrate this technology in full-scale engine tests. Volume 2 of the report includes the following appendices: Appendix A: Heater Head Development (Starfish Heater Head Program, 1/10th Segment and Full-Scale Heat Pipes, and Sodium Filling and Processing); Appendix B: Component Test Power Converter (CTPC) Component Development (High-temperature Organic Materials, Heat Exchanger Fabrication, Beryllium Issues, Sodium Issues, Wear Couple Tests, Pressure Boundary Penetrations, Heating System Heaters, and Cooler Flow Test); Appendix C: Udimet Testing (Selection of the Reference Material for the Space Stirling Engine Heater Head, Udimet 720LI Creep Test Result Update, Final Summary of Space Stirling Endurance Engine Udimet 720L1 Fatigue Testing Results, Udimet 720l1 Weld Development Summary, and Udimet 720L1 Creep Test Final Results Summary), and Appendix D: CTPC Component Development Photos.

  2. The Problematic Pipeline: Demographic Trends and Latino Participation in Graduate Science, Technology, Engineering, and Mathematics Programs

    Science.gov (United States)

    Chapa, Jorge; De La Rosa, Belinda

    2006-01-01

    This article addresses Latino population growth in the United States and their participation in higher education, particularly in science, technology, engineering, and mathematics programs. The demographic and educational trends outlined here suggest that although the Latino population will continue to grow very rapidly, the participation in…

  3. Successful Programs for Undergraduate Women in Science and Engineering: "Adapting" versus "Adopting" the Institutional Environment

    Science.gov (United States)

    Fox, Mary Frank; Sonnert, Gerhard; Nikiforova, Irina

    2009-01-01

    This article focuses upon programs for undergraduate women in science and engineering, which are a strategic research site in the study of gender, science, and higher education. The design involves both quantitative and qualitative approaches, linking theory, method, questions, and analyses in ways not undertaken previously. Using a comprehensive,…

  4. The Use of Engineering Design Concept for Computer Programming Course: A Model of Blended Learning Environment

    Science.gov (United States)

    Tritrakan, Kasame; Kidrakarn, Pachoen; Asanok, Manit

    2016-01-01

    The aim of this research is to develop a learning model which blends factors from learning environment and engineering design concept for learning in computer programming course. The usage of the model was also analyzed. This study presents the design, implementation, and evaluation of the model. The research methodology is divided into three…

  5. What Value Does Service Learning Have on Introductory Engineering Students' Motivation and ABET Program Outcomes?

    Science.gov (United States)

    Sevier, Carol; Chyung, Seung Youn; Callahan, Janet; Schrader, Cheryl B.

    2012-01-01

    A quasi-experimental study was conducted to investigate the effectiveness of using a service learning (SL) method on influencing introductory engineering students' motivation and ABET program outcomes, compared to the effectiveness of using a conventional, non-service-learning (NSL) method. The sample used in the study was 214 students enrolled in…

  6. Competencies Analysis in the Sustainable Development Field of Electrical Engineering Baccalaureate Program Alumni

    Directory of Open Access Journals (Sweden)

    Ivanova Veronica

    2015-01-01

    Full Text Available The term “sustainable development” is clarified. Criteria for the development of sustainable development in universities are selected. The analysis of the Electrical Engineering Baccalaureate Program for the development of competences for sustainable development is done. The conclusion about the need to develop smart university - sustainable development strategy of universities is made.

  7. Delivering an AS Engineering Degree Program to Home-Based Learners Using Affordable Multiple Media.

    Science.gov (United States)

    Sener, John

    1996-01-01

    Describes results of a project to develop a distance education associate in science (AS) engineering degree program through Northern Virginia Community College. Highlights include combining self-paced independent learning with interactive/collaborative learning asynchronously; transmitting graphics, equations, and formulas via computer-mediated…

  8. Vertical and Horizontal Integration of Laboratory Curricula and Course Projects across the Electronic Engineering Technology Program

    Science.gov (United States)

    Zhan, Wei; Goulart, Ana; Morgan, Joseph A.; Porter, Jay R.

    2011-01-01

    This paper discusses the details of the curricular development effort with a focus on the vertical and horizontal integration of laboratory curricula and course projects within the Electronic Engineering Technology (EET) program at Texas A&M University. Both software and hardware aspects are addressed. A common set of software tools are…

  9. Weapon System Requirements: Detailed Systems Engineering Prior to Product Development Positions Programs for Success

    Science.gov (United States)

    2016-11-01

    contractor subsequently discovered problems with the aircraft wiring and aerial refueling systems and encountered a fuel contamination incident, all...WEAPON SYSTEM REQUIREMENTS Detailed Systems Engineering Prior to Product Development Positions Programs for Success...Accountability Office Highlights of GAO-17-77, a report to congressional committees November 2016 WEAPON SYSTEM REQUIREMENTS Detailed Systems

  10. Evaluation of the Science, Technology, and Engineering Leadership Program, Year Three

    Science.gov (United States)

    Wolanin, Natalie; Wade, Julie

    2014-01-01

    The Office of Shared Accountability conducted an evaluation of the implementation of the third and final year (2012-2013) of the "Science, Technology, and Engineering Leadership Program" (STELP) in Montgomery County (Maryland) Public Schools (MCPS). Funding for STELP, including the evaluation study, is provided by a grant from the Howard…

  11. Evaluation of the Science, Technology, and Engineering Leadership Program, Year Two

    Science.gov (United States)

    Wolanin, Natalie L.; Wade, Julie H.

    2013-01-01

    The Office of Shared Accountability (OSA) conducted an evaluation of the implementation of the second year (2011-2012) of the Science, Technology, and Engineering Leadership Program (STELP) in Montgomery County (Maryland) Public Schools (MCPS). Funding for STELP, including the evaluation study, is provided by a grant from the Howard Hughes Medical…

  12. Mathematics Learning by Programming in a Game Engine: Development of Knowledge and Student Motivation

    DEFF Research Database (Denmark)

    Triantafyllou, Evangelia; Misfeldt, Morten; Timcenko, Olga

    2017-01-01

    traditional mathematics assignments with a programming project in a game engine (Unity) when teaching the reflection and refraction vector calculation. The main concept of this approach was that students get simple projects in Unity, where mathematics is used for game mechanics, and they have to modify...

  13. Human Research Program Integrated Research Plan. Revision C

    Science.gov (United States)

    Steinberg, Susan

    2011-01-01

    Crew health and performance are critical to successful human exploration beyond low Earth orbit. The Human Research Program (HRP) is essential to enabling extended periods of space exploration because it provides knowledge and tools to mitigate risks to human health and performance. Risks include physiological effects from radiation and hypogravity environments, as well as unique challenges in medical support, human factors, and behavioral or psychological factors. The Human Research Program (HRP) delivers human health and performance countermeasures, knowledge, technologies and tools to enable safe, reliable, and productive human space exploration. Without HRP results, NASA will face unknown and unacceptable risks for mission success and post-mission crew health. This Integrated Research Plan (IRP) describes (1) HRP's approach and research activities that are intended to address the needs of human space exploration and serve HRP customers and (2) the method of integration for risk mitigation. The scope of the IRP is limited to the activities that can be conducted with the resources available to the HRP; it does not contain activities that would be performed if additional resources were available. The timescale of human space exploration is envisioned to take many decades. The IRP illustrates the program s research plan through the timescale of early lunar missions of extended duration.

  14. Engineering bone tissue substitutes from human induced pluripotent stem cells

    National Research Council Canada - National Science Library

    Giuseppe Maria de Peppo; Iván Marcos-Campos; David John Kahler; Dana Alsalman; Linshan Shang; Gordana Vunjak-Novakovic; Darja Marolt

    2013-01-01

    ...) for bone tissue engineering. We first induced three hiPSC lines with different tissue and reprogramming backgrounds into the mesenchymal lineages and used a combination of differentiation assays, surface antigen profiling...

  15. Ideas in Practice: The Mississippi River: Humanities and Civil Engineering.

    Science.gov (United States)

    Vonalt, Larry; And Others

    1980-01-01

    Describes a course offered for the freshman civil engineering major at the University of Missouri-Rolla. The rationale of developing the course which focuses on the symbolic, social, and technological aspects of the Mississippi River is included. (HM)

  16. Development of Education Program Applying Internal Combustion Engine with Bioethanol as Fuel

    Science.gov (United States)

    Utsumi, Noah; Yoshida, Masashi; Inada, Yuji

    One of the ways to mitigate global warming is to reduce carbon dioxide emissions. In Japan, carbon dioxide emissions from vehicles, which run on fossil fuels, account for about 1/4 of the total carbon dioxide emissions. In this study, we applied a commercial engine, and remodeled the engine which could work using bioethanol as a fuel. We subsequently examined the influence of exhaust emission of the engine with the bioethanol and documented the entire study as teaching materials, including the remodeling method. Next, we began our mechanical engineering courses at the university by using the teaching materials in this study as introductory education, with the aim of stimulating the interest of the students. We then developed an education program for the students.

  17. A data base and analysis program for shuttle main engine dynamic pressure measurements

    Science.gov (United States)

    Coffin, T.

    1986-01-01

    A dynamic pressure data base management system is described for measurements obtained from space shuttle main engine (SSME) hot firing tests. The data were provided in terms of engine power level and rms pressure time histories, and power spectra of the dynamic pressure measurements at selected times during each test. Test measurements and engine locations are defined along with a discussion of data acquisition and reduction procedures. A description of the data base management analysis system is provided and subroutines developed for obtaining selected measurement means, variances, ranges and other statistics of interest are discussed. A summary of pressure spectra obtained at SSME rated power level is provided for reference. Application of the singular value decomposition technique to spectrum interpolation is discussed and isoplots of interpolated spectra are presented to indicate measurement trends with engine power level. Program listings of the data base management and spectrum interpolation software are given. Appendices are included to document all data base measurements.

  18. Comprehensive approach to photonics education for technicians, engineers, and scientists in 4+2+2 programs

    Science.gov (United States)

    Pedrotti, Leno S.; Massa, Nicholas J.; Soulsby, Eric P.; Enderle, John; Roychoudhuri, Chandrasekhar

    1995-10-01

    This paper outlines a curricular plan for the education of photonics technicians, engineers, and scientists in 4 + 2 + 2 programs. These programs begin at the 9th grade in high school and end either at the 14th grade (4 + 2 programs) with an associate of applied science degree, or at the 16th grade (4 + 2 + 2 programs) with a bachelor of science degrees. Beginning with comprehensive lists of appropriate tasks for photonics technicians - as identified by phonics-related industries - extrapolation is made to specific courses, sequences of courses, and suggested programs. The foundations are set in place first in four-year high school programs, with emphasis on basics in mathematics, science, communications and introductory technology courses. The postsecondary level programs, through the 13th and 14th year, present the breadth and depth of skills required for the development of entry-level photonics technicians. Finally articulated programs from two-year colleges on to four-year colleges are outlined for those who opt to continue on for a bachelor of science degree and who plan to enter the phonics workforce with concentration in electrical engineering and/or optics.

  19. Variable Cycle Engine Control System Definition Study. Turbine Engine Technology Demonstrator Component Development Program, Project 668A. Controls Development Program

    Science.gov (United States)

    1976-03-01

    with a contvol system was developed along with cOMUtet.-ed optimi.-ation ard conetraint proedure... to e-totlish optimal enine jam• ?a. ... O1 • j1.4St 1...self-test and diagnostic features of the controller software . It should be noted from a systems concept that failure detection applies to both the...deve’..., and validation of software for implementing the final control mode for the J.:-’on-, strator test stand running. The test program also

  20. Training in Human Relations for Engineers at the Ecole Superieure D'Informatique-Electronique-Automatique (ESIEA).

    Science.gov (United States)

    Lafargue, M.; And Others

    1986-01-01

    Points out the need to provide engineers with training in human relations. Describes the process of developing a document defining the problem and steps to be taken toward solution, submitted to students for their evaluation. (JM)

  1. Training in Human Relations for Engineers at the Ecole Superieure D'Informatique-Electronique-Automatique (ESIEA).

    Science.gov (United States)

    Lafargue, M.; And Others

    1986-01-01

    Points out the need to provide engineers with training in human relations. Describes the process of developing a document defining the problem and steps to be taken toward solution, submitted to students for their evaluation. (JM)

  2. Reverse engineering GTPase programming languages with reconstituted signaling networks.

    Science.gov (United States)

    Coyle, Scott M

    2016-07-02

    The Ras superfamily GTPases represent one of the most prolific signaling currencies used in Eukaryotes. With these remarkable molecules, evolution has built GTPase networks that control diverse cellular processes such as growth, morphology, motility and trafficking. (1-4) Our knowledge of the individual players that underlie the function of these networks is deep; decades of biochemical and structural data has provided a mechanistic understanding of the molecules that turn GTPases ON and OFF, as well as how those GTPase states signal by controlling the assembly of downstream effectors. However, we know less about how these different activities work together as a system to specify complex dynamic signaling outcomes. Decoding this molecular "programming language" would help us understand how different species and cell types have used the same GTPase machinery in different ways to accomplish different tasks, and would also provide new insights as to how mutations to these networks can cause disease. We recently developed a bead-based microscopy assay to watch reconstituted H-Ras signaling systems at work under arbitrary configurations of regulators and effectors. (5) Here we highlight key observations and insights from this study and propose extensions to our method to further study this and other GTPase signaling systems.

  3. Environmental Science and Engineering Merit Badges: An Exploratory Case Study of a Non-Formal Science Education Program and the U.S. Scientific and Engineering Practices

    Science.gov (United States)

    Vick, Matthew E.; Garvey, Michael P.

    2016-01-01

    The Boy Scouts of America's Environmental Science and Engineering merit badges are two of their over 120 merit badges offered as a part of a non-formal educational program to U.S. boys. The Scientific and Engineering Practices of the U.S. Next Generation Science Standards provide a vision of science education that includes integrating eight…

  4. Phase 2 Clinical Trial of Intraoral Grafting of Human Tissue-Engineered Oral Mucosa

    Science.gov (United States)

    2013-10-01

    Engineered Oral Mucosa   PRINCIPAL INVESTIGATOR: Stephen E. Feinberg DDS, MS, PhD CONTRACTING ORGANIZATION: University of Michigan Ann Arbor MI 4810...September 29, 4. TITLE AND SUBTITLE Phase II Clinical Trial of Intraoral Grafting of Human Tissue-Engineered Oral Mucosa   5a. CONTRACT NUMBER...human EVPOME for soft tissue intraoral grafting procedures compared to the “gold standard” palatal oral mucosa (POM) graft. The study will determine

  5. Genetic engineering of human ES and iPS cells using TALE nucleases

    OpenAIRE

    Hockemeyer, Dirk; Wang, Haoyi; Kiani, Samira; Lai, Christine S.; Gao, Qing; Cassady, John P.; Cost, Gregory J.; Zhang, Lei; Santiago, Yolanda; Miller, Jeffrey C; Zeitler, Bryan; Cherone, Jennifer M.; Meng, Xiangdong; Hinkley, Sarah J; Rebar, Edward J.

    2011-01-01

    Targeted genetic engineering of human pluripotent cells is a prerequisite for exploiting their full potential. Such genetic manipulations can be achieved using site-specific nucleases. Here we engineered transcription activator–like effector nucleases (TALENs) for five distinct genomic loci. At all loci tested we obtained human embryonic stem cell (ESC) and induced pluripotent stem cell (iPSC) clones carrying transgenic cassettes solely at the TALEN-specified location. Our data suggest that T...

  6. The program cyberdiesel for mathematical modeling of fuel supply and local intracylinder processes in a diesel engine with volumetric carburetion

    OpenAIRE

    Maschenko, V. Yu.

    2007-01-01

    The program CyberDiesel is developed on the basis of complex mathematical model of fuel supply and local intracylinder processes in a diesel engine with volumetric carburetion. The program is intended for solving practical problems of coordinating constructive and adjusting parameters of fuel equipment and combustion chamber of a diesel engine by mathematical modeling methods.

  7. Retention and Recruitment Programs for Female Undergraduate Students in Engineering at The University of Toledo, Ohio, USA

    Science.gov (United States)

    Franchetti, Matthew; Ravn, Tina; Kuntz, Vicki L.

    2010-01-01

    This paper summarizes the findings of a five year study aimed at improving both recruitment and retention of female students pursuing careers in engineering. The study analyzed a series of five programs implemented at the College of Engineering at The University of Toledo in Ohio, USA. The effectiveness of the programs over time is measured from…

  8. IN VITRO EFFECT OF SILVER ENGINEERED NANOPARTICLES ON HUMAN SPERMATOZOA

    Directory of Open Access Journals (Sweden)

    G. Terzuoli

    2012-08-01

    Full Text Available Silver (Ag NPs are among the most commercialized NPs due to their antimicrobial potential. They are highly at- tractive for possible applications in manufacture of medical device. However there is a serious lack of information concerning their impact on the human health and the environment. Moreover studies on the effects of NPs on ejaculated sperm are rather limited. For these reasons our study explored the in vitro effects of Ag NPs on human ejaculated spermatozoa. Ag NPs have been produced, characterized, and furnished by Colorobbia Industry, Sovigliana (Vinci, Florence, Italy. Aliquots of total semen were incubated at 37°C for 60 minutes (min and 120 min at the concentration of 125 μM, 250 μM, and 500 μM of engineered Ag NPs. The control was represented by specimens of semen samples treated with the same procedure without NPs. After the incubations, sperm motility was evaluated following WHO guidelines and sperm viability was eval- uated by Eosin Y test. At the end of incubation with Ag NPs the samples were processed by a Field Emission Gun-based Scanning Transmition Electron Microscope/ Energy Dispertion Spectrometry (STEM/EDS. We observed that sperm motility percentage was significantly reduced in semen samples treated with 125 μM, 250 μM and 500 μM of Ag NPs after 60 min and 120 min of incubation respect to controls (P<0.001; P<0.01, 125 μM at 60 min. Sperm viability percentage significantly decreased in a progressive manner after 125 μM (P<0.05, 250 μM (P<0.05 and 500 μM (P<0.001 Ag NPs incubation at 60 min and 120 min. We did not find any significant difference between the values assessed after 60 min of NPs incubation and those estimated after 120 min of incubation. In the control samples, the sperm motility and the sperm viability percentages significantly decreased after 120 min of incubation (P<0.001 respect to the basal values. Ag NPs were undetectable in all treated samples by STEM/EDS. These in vitro results show a

  9. Usability: Human Research Program - Space Human Factors and Habitability

    Science.gov (United States)

    Sandor, Aniko; Holden, Kritina L.

    2009-01-01

    The Usability project addresses the need for research in the area of metrics and methodologies used in hardware and software usability testing in order to define quantifiable and verifiable usability requirements. A usability test is a human-in-the-loop evaluation where a participant works through a realistic set of representative tasks using the hardware/software under investigation. The purpose of this research is to define metrics and methodologies for measuring and verifying usability in the aerospace domain in accordance with FY09 focus on errors, consistency, and mobility/maneuverability. Usability metrics must be predictive of success with the interfaces, must be easy to obtain and/or calculate, and must meet the intent of current Human Systems Integration Requirements (HSIR). Methodologies must work within the constraints of the aerospace domain, be cost and time efficient, and be able to be applied without extensive specialized training.

  10. Utilization Practice of the Concept Mapping Program for Nuclear Engineer Training

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Bae Joo; Ko, Byung Moo; Heo, Yuk [Korea Hydro and Nuclear Power, Daejeon (Korea, Republic of)

    2009-05-15

    Knowledge is the most important factor in the safe and reliable operation of the NPP. Many methods are used to enhance the knowledge level of the personnel in the NPP. Generally, classroom lecture method is used for nuclear engineers. But this method has some pitfalls as an adult training method because students have already a lot of knowledge, so they want to participate actively in the learning process. KNPEI undertook a research project from March 2006 to September 2007 to capture the experience knowledge from senior staff and transfer it to junior staff. As part of the research activity KNPEI introduced a Concept Mapping Program and set up a Concept Mapping server to capture the experience knowledge of the senior staff. This Concept Mapping Program has some characteristics that can be used in learning about conceptual knowledge. The purpose of this report is to introduce the utilization method and practice at KNPEI for the nuclear engineer training using the Concept Mapping Program.

  11. Program of “Okayama Biomedical Engineering Professional” for Local Renovation

    Science.gov (United States)

    Hayashi, Kozaburo

    Okayama University of Science, Department of Biomedical Engineering, is promoting a program of “Okayama Biomedical Engineering Professional” for the development and renovation of biomedical industries in Okayama area. This is one of the programs of the national project on “Formation of the Center for the Production of Capable Persons for Local Renovation” , sponsored by the Ministry of Education, Culture, Sports, Science and Technology, Japan, and performed by the Japan Science and Technology Agency. The purpose of the program is to develop and educate specialists for the research, development, production, and marketing of biomedical devices and equipment in local industries in Okayama area. A half a year training for approximately 5 students from industries consists of 12 days of lectures and experiments, which is repeatedly provided for 5 years (approximately 45 students in total) .

  12. Assessing and mitigating risks of engineering programs with lean management techniques

    DEFF Research Database (Denmark)

    Fritz, A.; Oehmen, Josef; Rebentisch, E.

    2014-01-01

    This paper investigates the use of lean management techniques as a risk mitigation approach for large-scale engineering programs. The key research questions are how lean best practices with the highest risk mitigation potential are identified, how the most relevant lean best practices for a speci......This paper investigates the use of lean management techniques as a risk mitigation approach for large-scale engineering programs. The key research questions are how lean best practices with the highest risk mitigation potential are identified, how the most relevant lean best practices...... in higher risks, which can lead to significant cost-overruns and large delays in schedule [Oehmen et al. 2012, Cantarelli et al. 2010, Flyvbjerg et al. 2003, GAO 2006]. Program success depends on four dimensions: delivery capability, organizational capability, marketing capability and innovative capability...

  13. NASA/American Society for Engineering Education (ASEE) Summer Faculty Fellowship Program 1989

    Science.gov (United States)

    Tiwari, Surendra N. (Compiler)

    1989-01-01

    Since 1964, NASA has supported a program of summer faculty fellowships for engineering and science educators. The objectives are: to further the professional knowledge of qualified engineering and science faculty; to stimulate and exchange ideas between participants and NASA; to enrich and refresh the research and teachning activities of participants' institutions; and to contribute to the research objectives of the NASA center. College or university faculty members will be appointed as Research Fellows to spend 10 weeks in cooperative research and study at the NASA Langley Research Center. The Fellow will devote approximately 90 percent of the time to a research problem and the remaining time to a study program. The study program will consist of lecture and seminars on topics of interest or that are directly relevant to the Fellows' research topic.

  14. Reframing Doctoral Programs: A Program of Human Inquiry for Doctoral Students and Faculty Advisors.

    Science.gov (United States)

    Shambaugh, R. Neal

    2000-01-01

    Proposes the Program of Human Inquiry as a framework for joint student-faculty portfolios by graduate students and faculty advisors. The program consists of four components: (1) acknowledgment of what one brings to graduate studies; (2) a plan of study, (3) a record of rigorous negotiated "avenues of inquiry," and (4) ongoing discussion of values…

  15. The Role of NSF's Department Level Reform Program in Engineering Education Practice and Research

    Science.gov (United States)

    Daniels, John L.; Wood, Sally L.; Kemnitzer, Susan C.

    2011-01-01

    Engineering education directly supports the nation's capacity for economic growth, infrastructure renewal, and security, as well as environmental and human health. Numerous reports have recommended federal support to advance our understanding of how students learn, how faculty teach, and how teaching and learning are assessed. The U.S. National…

  16. Human Sexuality Education in Marriage and Family Therapy Graduate Programs.

    Science.gov (United States)

    Zamboni, Brian D; Zaid, Samantha J

    2017-02-20

    Given the likelihood that marriage and family therapists will encounter clients with sexual concerns, it is important to know how graduate training programs are preparing future clinicians to work with this domain of life. Sixty-nine marriage and family therapy (MFT) program directors completed an online survey to examine how sexual health education is integrated into graduate training programs. Findings indicate that while the majority of program directors value sexuality curriculum, and most programs require at least one course in this area, there are barriers to privileging sex topics in MFT graduate programs. Barriers include few MFT faculties with expertise in human sexuality and marginalized sexual health topics. Implications for training MFT graduate students and their work with future clients are discussed.

  17. Numerical analysis of stiffened shells of revolution. Volume 4: Engineer's program manual for STARS-2S shell theory automated for rotational structures - 2 (statics) digital computer program

    Science.gov (United States)

    Svalbonas, V.; Ogilvie, P.

    1973-01-01

    The engineering programming information for the digital computer program for analyzing shell structures is presented. The program is designed to permit small changes such as altering the geometry or a table size to fit the specific requirements. Each major subroutine is discussed and the following subjects are included: (1) subroutine description, (2) pertinent engineering symbols and the FORTRAN coded counterparts, (3) subroutine flow chart, and (4) subroutine FORTRAN listing.

  18. An Engine Research Program Focused on Low Pressure Turbine Aerodynamic Performance

    Science.gov (United States)

    Castner, Raymond; Wyzykowski, John; Chiapetta, Santo; Adamczyk, John

    2002-01-01

    A comprehensive test program was performed in the Propulsion Systems Laboratory at the NASA Glenn Research Center, Cleveland Ohio using a highly instrumented Pratt and Whitney Canada PW 545 turbofan engine. A key objective of this program was the development of a high-altitude database on small, high-bypass ratio engine performance and operability. In particular, the program documents the impact of altitude (Reynolds Number) on the aero-performance of the low-pressure turbine (fan turbine). A second objective was to assess the ability of a state-of-the-art CFD code to predict the effect of Reynolds number on the efficiency of the low-pressure turbine. CFD simulation performed prior and after the engine tests will be presented and discussed. Key findings are the ability of a state-of-the art CFD code to accurately predict the impact of Reynolds Number on the efficiency and flow capacity of the low-pressure turbine. In addition the CFD simulations showed the turbulent intensity exiting the low-pressure turbine to be high (9%). The level is consistent with measurements taken within an engine.

  19. Approaches to Software Engineering: A Human-Centred Perspective

    OpenAIRE

    Bannon, Liam J.

    2010-01-01

    International audience; The field of software engineering has been evolving since its inception in 1968. Arguments as to the exact nature of the field, whether it should be conceived as a real engineering profession, the role of formal methods, whether it is as much an art as a science, etc., continue to divide both practitioners and academics. My purpose here is not to debate these particular topics, but rather to approach the field from the outside, coming as I do from a long period of invo...

  20. Overview of CMC Development Activities in NASA's Ultra-Efficient Engine Technology (UEET) Program

    Science.gov (United States)

    Brewer, Dave

    2001-01-01

    The primary objective of the UEET (Ultra-Efficient Engine Technology) Program is to address two of the most critical propulsion issues: performance/efficiency and reduced emissions. High performance, low emissions engine systems will lead to significant improvement in local air quality, minimum impact on ozone depletion and level to an overall reduction in aviation contribution to global warming. The Materials and Structures for High Performance project will develop and demonstrate advanced high temperature materials to enable high-performance, high efficiency, and environmentally compatible propulsion systems.

  1. PREP Program: High school urban engineering technical progress report, Summer 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    The Urban Engineering Program at the New Jersey Institute of Technology which as its primary objective is to introduce the students to the excitement of science and engineering as potential career opportunities, and to encourage the youngsters to adequately prepare in high school and in college for such an attainable endeavor. Through the course work, workshops, projects, guest speakers, and laboratory experiences, the students are not only introduced to the problems in urban areas, but also are introduced to the tools and analysis available to solve such problems.

  2. A descriptive study of the barriers to study abroad in engineering undergraduate education and recommendations for program design

    Science.gov (United States)

    Klahr, Sabine Christine

    This study analyzed and compared the program designs of international exchange and internship programs for engineering students in the United States and the European Union (E.U.) as well as the extent to which these programs have removed barriers to study abroad. The purpose of this study was to provide recommendations for the design of international programs in the U.S. that would increase the proportion of engineering students who choose to study or intern abroad. Coordinators of international programs in engineering were surveyed about their perceptions of program success and a number of variables related to program design. A Chi-Square Test of Independence of (A) program success and (B) European and U.S. programs (i.e. institution location) cross-tabulated with all other variables and each other indicated those variables that contribute to the success of programs and those variables that are associated with either U.S. or European programs. In addition, all programs were described and the answers to open-ended survey questions were analyzed quantitatively. The analyses indicated that European programs tend to be more successful in implementing study/intern abroad programs for engineering students than U.S. programs. The elements of program design contributing to the greater success of European programs and the success of specific U.S. programs were described. In addition, the characteristics of overall successful programs (U.S. and E.U. data combined) were explained. The results indicated that successful programs tend to: (1) be promoted by the college and/or departments of engineering, (2) offer study/intern abroad opportunities in English-speaking settings, (3) award full credit at the home institution for required engineering courses completed at the host institution, (4) offer scholarships and financial aid for participation in the program, (5) require participating students to have completed their second year of university course work prior to applying to

  3. Employability of Engineering Graduates from 2013 to 2015 as Basis for a Proposed Student Development Program

    Directory of Open Access Journals (Sweden)

    Nemy H. Chavez

    2017-02-01

    Full Text Available This study aims to determine the employability of Mechanical, Industrial and Electronics Engineering graduates which also explores the relevance of curriculum and work-related behavior to the job placement of the graduate-respondents. Descriptive type of research was utilized in the study. Findings showed that engineering graduates of the academic institution under study are highly employable and gainfully employed locally while enjoying the benefits of regular status and handling professional, technical or supervisory positions where they find their present jobs within 1 to 6 months. Relevance of the engineering program to graduates’ present work assignment is one of the common reasons in accepting and staying on the job while communication skill is the most common useful ability of the engineering graduates in their job placement and leadership, hard work and professional integrity are the work – related values identified with very much contribution in meeting the demands of their present employment. Curriculum is also considered relevant for Mechanical and Industrial Engineering graduates but only slightly relevant for Electronics Engineering Graduates.

  4. The Barrett Foundation: Undergraduate Research Program for Environmental Engineers and Scientists

    Science.gov (United States)

    Rizzo, D. M.; Paul, M.; Farmer, C.; Larson, P.; Matt, J.; Sentoff, K.; Vazquez-Spickers, I.; Pearce, A. R.

    2007-12-01

    A new program sponsored by The Barrett Foundation in the University of Vermont College of Engineering and Mathematical Sciences (UVM) supports undergraduate students in Environmental Engineering, Earth and Environmental Sciences to pursue independent summer research projects. The Barrett Foundation, a non-profit organization started by a UVM Engineering alum, provided a grant to support undergraduate research. Students must work with at least two different faculty advisors to develop project ideas, then independently prepare a research proposal and submit it to a faculty panel for review. The program was structured as a scholarship to foster a competitive application process. In the last three years, fourteen students have participated in the program. The 2007 Barrett Scholars projects include: - Using bacteria to change the chemistry of subsurface media to encourage calcite precipitation for soil stability and pollutant sequestration - Assessing structural weaknesses in a historic post and beam barn using accelerometers and wireless data collection equipment - Using image processing filters to 1) evaluate leaf wetness, a leading indicator of disease in crops and 2) assess the movement of contaminants through building materials. - Investigating the impact of increased water temperature on cold-water fish species in two Vermont streams. - Studying the impacts of light duty vehicle tailpipe emissions on air quality This program supports applied and interdisciplinary environmental research and introduces students to real- world engineering problems. In addition, faculty from different research focuses are presented the opportunity to establish new collaborations around campus through the interdisciplinary projects. To date, there is a successful publication record from the projects involving the Barrett scholars, including students as authors. One of the objectives of this program was to provide prestigious, competitive awards to outstanding undergraduate engineers

  5. Genome engineering of isogenic human ES cells to model autism disorders.

    Science.gov (United States)

    Martinez, Refugio A; Stein, Jason L; Krostag, Anne-Rachel F; Nelson, Angelique M; Marken, John S; Menon, Vilas; May, Ryan C; Yao, Zizhen; Kaykas, Ajamete; Geschwind, Daniel H; Grimley, Joshua S

    2015-05-26

    Isogenic pluripotent stem cells are critical tools for studying human neurological diseases by allowing one to study the effects of a mutation in a fixed genetic background. Of particular interest are the spectrum of autism disorders, some of which are monogenic such as Timothy syndrome (TS); others are multigenic such as the microdeletion and microduplication syndromes of the 16p11.2 chromosomal locus. Here, we report engineered human embryonic stem cell (hESC) lines for modeling these two disorders using locus-specific endonucleases to increase the efficiency of homology-directed repair (HDR). We developed a system to: (1) computationally identify unique transcription activator-like effector nuclease (TALEN) binding sites in the genome using a new software program, TALENSeek, (2) assemble the TALEN genes by combining golden gate cloning with modified constructs from the FLASH protocol, and (3) test the TALEN pairs in an amplification-based HDR assay that is more sensitive than the typical non-homologous end joining assay. We applied these methods to identify, construct, and test TALENs that were used with HDR donors in hESCs to generate an isogenic TS cell line in a scarless manner and to model the 16p11.2 copy number disorder without modifying genomic loci with high sequence similarity.

  6. Cultivating Engineers' Humanity: Fostering Cosmopolitanism in a Technical University

    Science.gov (United States)

    Boni, Alejandra; MacDonald, Penny; Peris, Jordi

    2012-01-01

    This paper aims to explore the potential of a curriculum designed to develop Nussbaum's cosmopolitan abilities through two elective subjects offered to future engineers in a Spanish Technical University. To this end, Nussbaum's proposition of cosmopolitan abilities is presented in relation to the broader academic literature on cosmopolitanism and…

  7. Musculoskeletal tissue engineering with human umbilical cord mesenchymal stromal cells

    Science.gov (United States)

    Wang, Limin; Ott, Lindsey; Seshareddy, Kiran; Weiss, Mark L; Detamore, Michael S

    2011-01-01

    Multipotent mesenchymal stromal cells (MSCs) hold tremendous promise for tissue engineering and regenerative medicine, yet with so many sources of MSCs, what are the primary criteria for selecting leading candidates? Ideally, the cells will be multipotent, inexpensive, lack donor site morbidity, donor materials should be readily available in large numbers, immunocompatible, politically benign and expandable in vitro for several passages. Bone marrow MSCs do not meet all of these criteria and neither do embryonic stem cells. However, a promising new cell source is emerging in tissue engineering that appears to meet these criteria: MSCs derived from Wharton’s jelly of umbilical cord MSCs. Exposed to appropriate conditions, umbilical cord MSCs can differentiate in vitro along several cell lineages such as the chondrocyte, osteoblast, adipocyte, myocyte, neuronal, pancreatic or hepatocyte lineages. In animal models, umbilical cord MSCs have demonstrated in vivo differentiation ability and promising immunocompatibility with host organs/tissues, even in xenotransplantation. In this article, we address their cellular characteristics, multipotent differentiation ability and potential for tissue engineering with an emphasis on musculoskeletal tissue engineering. PMID:21175290

  8. Human Resources Development in the Field of Electrical Engineering

    Science.gov (United States)

    Ishigame, Atsushi

    It is becoming increasingly clear that the decline in popularity in the field of electrical engineering is undergoing rapidly due to the fact that more young people are moving away from the science. The primary goal of this paper is to recognize the importance of educational new effort and, second, suggest social-provided education support needed to meet this challenge.

  9. Critical assessment and outlook for the 50 biomedical engineering undergraduate programs in Mexico.

    Science.gov (United States)

    Azpiroz-Leehan, Joaquín; Martínez Licona, Fabiola; Urbina Medal, E Gerardo; Cadena Méndez, Miguel; Sacristán Rock, Emilio

    2015-01-01

    Biomedical Engineering (BME) has been taught in Mexico at the undergraduate level for over forty years. The rationale for the introduction of this profession was to help manage and maintain the growing technological infrastructure in the health care system during the seventies. Owing to this, it is not surprising that early versions of the BME curricula were oriented towards clinical engineering and medical instrumentation. In the last decade the number of programs has grown from three in the seventies and eighties to fifty at present. This work is the result of the analysis of the BME programs in all the institutions that offer this degree in Mexico. Three main issues were studied: the curricula, the sub-disciplines that were emphasized in the programs and the job market. Results have shown a striking resemblance in most of the programs, which are mostly dedicated to teaching aspects of medical instrumentation and clinical engineering. These results reflect an agreement with the requirements of the job market, but since most job offerings are for low-paying positions in sales, service and hospital maintenance, we question the wisdom of stressing these sub-specialties at research universities, where faculties and research labs offer a wide variety of options. An analysis of work at these centers shows that most of the results are publications, so the need to emphasize translational research and partnerships with industry are suggested.

  10. Real-time Kernel Implementation Practice Program for Embedded Software Engineers' Education and its Evaluation

    Science.gov (United States)

    Yoshida, Toshio; Matsumoto, Masahide; Seo, Katsuhiko; Chino, Shinichiro; Sugino, Eiji; Sawamoto, Jun; Koizumi, Hisao

    A real-time kernel (henceforth RTK) is in the center place of embedded software technology, and the understanding of RTK is indispensable for the embedded system design. To implement RTK, it is necessary to understand languages that describe RTK software program code, system programming manners, software development tools, CPU on that RTK runs and the interface between software and hardware, etc. in addition to understanding of RTK itself. This means RTK implementation process largely covers embedded software implementation process. Therefore, it is thought that RTK implementation practice program is very effective as a means of the acquisition of common embedded software skill in addition to deeper acquisition of RTK itself. In this paper, we propose to apply RTK implementing practice program to embedded software engineers educational program. We newly developed very small and step-up type RTK named μK for educational use, and held a seminar that used μK as a teaching material for the students of information science and engineers of the software house. As a result, we confirmed that RTK implementation practice program is very effective for the acquisition of embedded software common skill.

  11. Decellularization of human and porcine lung tissues for pulmonary tissue engineering.

    Science.gov (United States)

    O'Neill, John D; Anfang, Rachel; Anandappa, Annabelle; Costa, Joseph; Javidfar, Jeffrey; Wobma, Holly M; Singh, Gopal; Freytes, Donald O; Bacchetta, Matthew D; Sonett, Joshua R; Vunjak-Novakovic, Gordana

    2013-09-01

    The only definitive treatment for end-stage organ failure is orthotopic transplantation. Lung extracellular matrix (LECM) holds great potential as a scaffold for lung tissue engineering because it retains the complex architecture, biomechanics, and topologic specificity of the lung. Decellularization of human lungs rejected from transplantation could provide "ideal" biologic scaffolds for lung tissue engineering, but the availability of such lungs remains limited. The present study was designed to determine whether porcine lung could serve as a suitable substitute for human lung to study tissue engineering therapies. Human and porcine lungs were procured, sliced into sheets, and decellularized by three different methods. Compositional, ultrastructural, and biomechanical changes to the LECM were characterized. The suitability of LECM for cellular repopulation was evaluated by assessing the viability, growth, and metabolic activity of human lung fibroblasts, human small airway epithelial cells, and human adipose-derived mesenchymal stem cells over a period of 7 days. Decellularization with 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate (CHAPS) showed the best maintenance of both human and porcine LECM, with similar retention of LECM proteins except for elastin. Human and porcine LECM supported the cultivation of pulmonary cells in a similar way, except that the human LECM was stiffer and resulted in higher metabolic activity of the cells than porcine LECM. Porcine lungs can be decellularized with CHAPS to produce LECM scaffolds with properties resembling those of human lungs, for pulmonary tissue engineering. We propose that porcine LECM can be an excellent screening platform for the envisioned human tissue engineering applications of decellularized lungs. Copyright © 2013 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  12. Goal Programming for Stable Mode Transition in Tandem Turbo-ramjet Engines

    Institute of Scientific and Technical Information of China (English)

    Chen Min; Tang Hailong; Zhu Zhili

    2009-01-01

    This article, in order to guarantee the stable mode transition in tandem turbo-ramjet engines, investigates the multi-objective and multi-variable goal programming algorithm. First, it introduces the structural features of the variable cycle turbo-ramjet engines, the principles of selecting the mode transition operation point and the design parameters, and the characteristics of the turbofan mode and the ramjet mode. Second, a component-based variable cycle turbo-ramjet engine model is developed to simulate the mode transition process. Third, the Newton-Raphson algorithm is used to solve the multi-variable and multi-objective optimization problem. The results show that with the maximum residua of only 0.06%, this algorithm has an acceptable convergence that meets the predetermined goals. Finally, the simulation shows that the stable turbo-ramjet mode transition could be realized with the mode transition control law developed by the algorithm.

  13. A quadratic programming framework for constrained and robust jet engine health monitoring

    Science.gov (United States)

    Borguet, S.; Léonard, O.

    2009-09-01

    Kalman filters are largely used in the jet engine community for condition monitoring purpose. This algorithm gives a good estimate of the engine condition provided that the residuals between the model prediction and the measurements are zero-mean, Gaussian random variables. In the case of sensor faults, this assumption does not hold anymore and consequently, the diagnosis is spoiled. This contribution presents a recursive estimation algorithm based on a Quadratic Programming (QP) formulation which provides robustness against sensor faults and allows constraints on the health parameters to be specified. The improvements in estimation accuracy brought by this new algorithm are illustrated on a series of typical test-cases that may be encountered on current turbofan engines.

  14. Human resource practices as predictors of engineering staff's organisational commitment

    National Research Council Canada - National Science Library

    Melinde Coetzee; Jeremy Mitonga-Monga; Benita Swart

    2014-01-01

      Human resource practices are an important means of retaining professionally qualified employees and improving and increasing their future level of organisational performance in today's turbulent...

  15. Using human factors engineering to improve the effectiveness of infection prevention and control.

    Science.gov (United States)

    Anderson, Judith; Gosbee, Laura Lin; Bessesen, Mary; Williams, Linda

    2010-08-01

    Human factors engineering is a discipline that studies the capabilities and limitations of humans and the design of devices and systems for improved performance. The principles of human factors engineering can be applied to infection prevention and control to study the interaction between the healthcare worker and the system that he or she is working with, including the use of devices, the built environment, and the demands and complexities of patient care. Some key challenges in infection prevention, such as delayed feedback to healthcare workers, high cognitive workload, and poor ergonomic design, are explained, as is how human factors engineering can be used for improvement and increased compliance with practices to prevent hospital-acquired infections.

  16. Customer satisfaction planning and industrial engineering move hospital towards in-house stockless program.

    Science.gov (United States)

    Burton, R; Mauk, D

    1993-03-01

    By integrating customer satisfaction planning and industrial engineering techniques when examining internal costs and efficiencies, materiel managers are able to better realize what concepts will best meet their customers' needs. Defining your customer(s), applying industrial engineering techniques, completing work sampling studies, itemizing recommendations and benefits to each alternative, performing feasibility and cost-analysis matrixes and utilizing resources through productivity monitoring will get you on the right path toward selecting concepts to use. This article reviews the above procedures as they applied to one hospital's decision-making process to determine whether to incorporate a stockless inventory program. Through an analysis of customer demand, the hospital realized that stockless was the way to go, but not by outsourcing the function--the hospital incorporated an in-house stockless inventory program.

  17. Applying an innovative educational program for the education of today's engineers

    Science.gov (United States)

    Kans, M.

    2012-05-01

    Engineers require a broad spectrum of knowledge and skills: basic skills in mathematics and physics, skills and competencies within the major subject area as well as more general knowledge about business and enterprise contexts, society regulations and understanding of the future professions' characteristics. In addition, social, intercultural, analytical and managing competencies are desired. The CDIO educational program was initiated as a means to come closer to practice and to assure the training of engineering skills that are required of today's engineers. CDIO is short for Conceive-Design-Implement-Operate and describes the full life cycle understanding of a system or asset that engineering students should reach during education. The CDIO initiative is formulated in a program consisting of two important documents: the CDIO standards and the CDIO syllabus. The standards describe a holistic approach on education, from knowledge and skills to be trained, how to train and assess them, to how to develop the teaching staff and the work places for enabling the goals. The specific knowledge and skills to be achieved are accounted for in the syllabus. In this paper we share our more than 15 years of experiences in problem and project based learning from the perspective of the CDIO standards. For each standard, examples of how to set up the education and overcome challenges connected to the standard are given. The paper concludes with recommendations to others wishing to work toward problem and real-life based education without compromising the requirements of a scientific approach.

  18. Colloquy and workshops: regional implications of the engineering manpower requirements of the National Energy Program

    Energy Technology Data Exchange (ETDEWEB)

    Segool, H. D. [ed.

    1979-05-01

    The crucial interrelationships of engineering manpower, technological innovation, productivity and capital re-formaton were keynoted. Near-term, a study has indicated a much larger New England energy demand-reduction/economic/market potential, with a probably larger engineering manpower requirement, for energy-conservation measures characterized by technological innovation and cost-effective capital services than for alternative energy-supply measures. Federal, regional, and state energy program responsibilities described a wide-ranging panorama of activities among many possible energy options which conveyed much endeavor without identifiable engineering manpower demand coefficients. Similarly, engineering manpower assessment data was described as uneven and unfocused to the energy program at the national level, disaggregated data as non-existent at the regional/state levels, although some qualitative inferences were drawn. A separate abstract was prepared for each of the 16 individual presentations for the DOE Energy Data Base (EDB); 14 of these were selected for Energy Abstracts for Policy Analysis (EAPA) and 2 for Energy Research Abstracts (ERA).

  19. Nuclear Engine System Simulation (NESS). Version 2.0: Program user's guide

    Science.gov (United States)

    Pelaccio, Dennis G.; Scheil, Christine M.; Petrosky, Lyman

    1993-01-01

    This Program User's Guide discusses the Nuclear Thermal Propulsion (NTP) engine system design features and capabilities modeled in the Nuclear Engine System Simulation (NESS): Version 2.0 program (referred to as NESS throughout the remainder of this document), as well as its operation. NESS was upgraded to include many new modeling capabilities not available in the original version delivered to NASA LeRC in Dec. 1991, NESS's new features include the following: (1) an improved input format; (2) an advanced solid-core NERVA-type reactor system model (ENABLER 2); (3) a bleed-cycle engine system option; (4) an axial-turbopump design option; (5) an automated pump-out turbopump assembly sizing option; (6) an off-design gas generator engine cycle design option; (7) updated hydrogen properties; (8) an improved output format; and (9) personal computer operation capability. Sample design cases are presented in the user's guide that demonstrate many of the new features associated with this upgraded version of NESS, as well as design modeling features associated with the original version of NESS.

  20. Is Law a Humanity: (Or Is It More like Engineering)?

    Science.gov (United States)

    Howarth, David

    2004-01-01

    Law often appears to be in a limbo between the Social Sciences and the Humanities. Movements within legal scholarship itself, the law and economics movement and the law and literature movement, represent efforts to portray law as a social science or as a humanity. But if one looks at what lawyers do, one finds that law is more like…

  1. Reverse Engineering Human Pathophysiology with Organs-on-Chips.

    Science.gov (United States)

    Ingber, Donald E

    2016-03-10

    While studies of cultured cells have led to new insights into biological control, greater understanding of human pathophysiology requires the development of experimental systems that permit analysis of intercellular communications and tissue-tissue interactions in a more relevant organ context. Human organs-on-chips offer a potentially powerful new approach to confront this long-standing problem.

  2. Engineering Substantially Prolonged Human Lifespans: Biotechnological Enhancement and Ethics

    NARCIS (Netherlands)

    Derkx, P.H.J.M.

    2006-01-01

    Substantial extension of the human lifespan has recently become a subject of lively debate. One reason for this is the completion in 2001 of the Human Genome Project and the experimental avenues for biogerontological research it has opened. Another is recent theoretical progress in biogerontology.

  3. ESES, a master's program in solar energy engineering at Dalarna University

    Energy Technology Data Exchange (ETDEWEB)

    Bales, C.; Broman, L.; Lindberg, E. [Solar Energy Research Center SERC, Dalarna Univ., Borlaenge (Sweden)

    2004-07-01

    The first group of students was admitted to the European Solar Engineering School, a master's level two-semester program at Dalarna University in Sweden, in August 1999. Now that the fifth group is all but through their year, some conclusions from our experiences are possible to draw. The paper gives the background of ESES, some information about how the program is arranged, and also some of the ESES staff experiences. Further information on ESES is found on www.eses.org. (orig.)

  4. Extensive Reading Program Which Changes Reluctant Engineering Students into Autonomous Learners of English

    Science.gov (United States)

    Nishizawa, Hitoshi; Yoshioka, Takayoshi; Itoh, Kazuaki

    This article introduces extensive reading (ER) as an approach to improve fundamental communication skills in English of reluctant EFL learners : average Japanese engineering students. It is distinct from concurrent translation approach from a perspective that the learners use English instead of Japanese to grasp the meaning of what they read and enjoy reading. In the ER program at Toyota National College of Technology, many students developed more positive attitude toward English, increased their reading speed, and achieved higher TOEIC scores, which was compared to those of the students before this ER program was introduced. Comparison between three groups of the students showed strong correlation between their TOEIC scores and the reading amount.

  5. An analysis of the aircraft engine Component Improvement Program (CIP) : a life cycle cost approach

    OpenAIRE

    Borer, Chris Joseph

    1990-01-01

    Approved for public release; distribution unlimited. Increasing budgetary constraints have prompted actions to reduce the maintenance cost of current naval aircraft. This thesis examines the Aircraft Engine Component Improvement Program (CIP), its impact on these cost at the organizational and intermediate levels of maintenance, and savings from these improvements. The objectives of the research were to identify current life cycle cost (LCC) models used by the Navy andor the other services...

  6. EDUCATIONAL COMPLEX ON ELECTRICAL ENGINEERING AND ELECTRONICS BASED ON MODELING IN PROGRAM TINA

    Directory of Open Access Journals (Sweden)

    Vladimir A. Alekhin

    2014-01-01

    Full Text Available The educational complex on the electrical engineering and electronics has been developed. It contains a course of lectures and lecture notes in the electronic form, a new computer laboratory practical work and practical training. All electronic manuals are based on modeling of electric and electronic circuits in the new effective program TINA. The educational complex is being successfully used in educational process on internal and distant learning. 

  7. Fostering Systems Engineering Education Through Interdisciplinary Programs and Graduate Capstone Projects

    Science.gov (United States)

    2011-06-01

    Technology, Engineering and Math (STEM) workforce. This problem goes beyond the needs of the core acquisition workforce that comprise only 40% of the...the higher levels of Bloom’s taxonomy. In the case of research based programs, students are evaluating and creating new methods and tools associated...AE students did not get involved in the concept definition or architecture development effort because they were unfamiliar with the methods and

  8. C-5 Reliability Enhancement and Re-engining Program (C-5 RERP)

    Science.gov (United States)

    2015-12-01

    Logistics ) C-5 RERP December 2015 SAR March 23, 2016 16:10:28 UNCLASSIFIED 4 Mr. Brian Townsend C-5 Division Mobility Directorate 2275 D Street...addition to new engines/pylons, C-5 RERP will provide upgrades to wing attachment fittings; new thrust reversers and auxiliary power units; upgrades...team successfully expedited delivery and fielding of updated C-5 software (Operational Flight Program version 3.5.2) and associated logistics support

  9. Human genome program report. Part 2, 1996 research abstracts

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-11-01

    This report contains Part 2 of a two-part report to reflect research and progress in the US Department of Energy Human Genome Program from 1994 through 1996, with specified updates made just before publication. Part 2 consists of 1996 research abstracts. Attention is focused on the following: sequencing; mapping; informatics; ethical, legal, and social issues; infrastructure; and small business innovation research.

  10. Human Genome Program Report. Part 2, 1996 Research Abstracts

    Science.gov (United States)

    1997-11-01

    This report contains Part 2 of a two-part report to reflect research and progress in the US Department of Energy Human Genome Program from 1994 through 1996, with specified updates made just before publication. Part 2 consists of 1996 research abstracts. Attention is focused on the following: sequencing; mapping; informatics; ethical, legal, and social issues; infrastructure; and small business innovation research.

  11. Residual shale-oil/diesel-engine operating compatibility program. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Burnett, M.; Derbidge, C.; Kuby, W.; Niven, H.; Richard, R.

    1983-10-01

    As part of a DOE study to determine the effective utilization of alternate fuels in medium-speed diesel engines, a residual shale oil (RSO) was fired in an APE-Allen, 1000-rpm, 9.5-in. bore diesel engine. Various fuel injection modes were considered. Based on a fuel characterization study and go/no-go tests, it was determined that the direct firing of 100 percent RSO gave performance comparable with that using No. 2 diesel fuel; consequently, performance/endurance tests were performed using 100 percent RSO. Conclusions of this test program are: Laboratory tests showed low levels of corrosion and deposit-causing elements. Therefore, corrosion and wear of engine components, when using RSO, should be no worse than for standard diesel fuel. The high wax content of RSO requires heating for supply, handling, and injection systems. Laboratory tests showed that the cetane number of RSO was equivalent to No. 2 diesel; hence, no engine modifications should be needed to burn RSO. The engine performance on RSO was essentially similar to standard diesel fuel. The thermal efficiency was slightly lower and Bosch smoke and particulates were slightly higher, especially at low load. Soft carbon deposits, formed on injectors when using RSO, did not affect performance. The 115-hour endurance test showed no significant performance deterioration. The deposit accumulation in combustion chambers and ports was not severe but was greater than standard diesel fuel would produce. Longer endurance tests are required to fully establish this conclusion. 41 figures, 21 tables.

  12. Establishment and characterization of human engineered cells stably expressing large extracellular matrix proteins.

    Science.gov (United States)

    Kwon, Daekee; Kang, Gwang-Sik; Han, Dong Keun; Park, Kwideok; Kim, Jae-Hwan; Lee, Soo-Hong

    2014-01-01

    Commercially available extracellular matrix (ECM) hydrogel-coated culture plates have been used to study the relationship between the ECM microenvironment and stem cell behavior. However, it is unclear whether ECM-coated dishes mimic the natural ECM microenvironment because the architecture of the ECM is constructed of randomly distributed fibers. The purpose of this study was the production and confirmation of human engineered cell lines stably expressing large ECM proteins such as collagen I/II and fibronectin. First, large (over 10 kb) ECM vectors encoding human collagen I/II and fibronectin were constructed and the circular vectors were linearized. Second, the linear ECM vectors were introduced into immortalized human embryonic kidney cells using various transfection methods. The polyethylenimine and liposome methods showed higher efficiencies than electroporation for transfection of these large vectors. Third, human ECM engineered cells were established by stable integration of the vector into the genomic DNA and resulted in stable overexpression of mRNA and proteins. In summary, human engineered cell lines stably expressing large ECM proteins such as human collagen I/II and fibronectin were successfully prepared, and secretion of the ECM components into the surrounding environment was confirmed by immunocytochemistry. Thus, human ECM engineered cells naturally secreting ECM components could be valuable for studying the relationship between the native ECM microenvironment and stem cell behavior.

  13. Intuitive engineering, human factors, and the design of future interfaces (Invited Paper)

    Science.gov (United States)

    Sampson, James B.

    2005-05-01

    Human factors engineering (HFE) professionals complain that they are often called in after-the-fact to help correct human interface problems. They believe many design flaws can be avoided if design teams involve them early on. However, in the case of innovative technology, such post hoc human factors may not be avoidable unless the inventor is also a human factors engineer or the prospective user. In rare cases an inventor of a new technology has an intuitive understanding of human engineering principles and knows well the capabilities and limitations of operators. This paper outlines the importance of focusing on the user-system interface and encouraging engineers to develop their own intuitive sense of users through mental imagery. If design engineers start with a clear mental picture of a specific user and task rather than generalities of use, fewer interface problems are likely to be encountered later in development. Successful technology innovators often use a visual thinking approach in the development of new concepts. Examples are presented to illustrate the successful application of intuitive design. An approach is offered on how designers can improve their non-verbal thinking skills. The author shares the view that the mission of HFE should not be to make system developers dependent on the small community of HF experts but rather to help them learn the value of applying user-centered design techniques.

  14. Human flexor tendon tissue engineering: decellularization of human flexor tendons reduces immunogenicity in vivo.

    Science.gov (United States)

    Raghavan, Shyam S; Woon, Colin Y L; Kraus, Armin; Megerle, Kai; Choi, Matthew S S; Pridgen, Brian C; Pham, Hung; Chang, James

    2012-04-01

    In mutilating hand injuries, tissue engineered tendon grafts may provide a reconstructive solution. We have previously described a method to decellularize cadaveric human flexor tendons while preserving mechanical properties and biocompatibility. The purpose of this study is to evaluate the immunogenicity and strength of these grafts when implanted into an immunocompetent rat model. Cadaveric human flexor tendons were divided into two groups. Group 1 was untreated, and Group 2 was decellularized by treatment with sodium dodecyl sulfate (SDS), ethylenediaminetetraacetic acid (EDTA), and peracetic acid (PAA). Both groups were then analyzed for the presence of major histocompatibility complexes by immunohistochemistry (IHC). Pair-matched tendons from each group were then placed into the dorsal subcutaneous tissue and anchored to the spinal ligaments of Wistar rats for 2 or 4 weeks, and harvested. The infiltration of B-cells and macrophages was determined using IHC. The explants where then subjected to mechanical testing to determine the ultimate tensile stress (UTS) and elastic modulus (EM). Statistical analysis was performed using a paired Student's t-test. The decellularization protocol successfully removed cells and MHC-1 complexes. At 2 weeks after implantation, there was increased infiltration of B-cells in Group 1 (untreated) compared with Group 2 (acellular), both in the capsule and tendon substance. There was improved ultimate tensile stress (UTS, 42.7 ± 8.3 vs. 22.8 ± 7.8 MPa, ptendons that were decellularized. At 4 weeks, there was continued B-cell infiltration in Group 1 (untreated) compared with Group 2 (acellular). There was no appreciable difference in macrophage infiltration at both time points. At 4 weeks Group 2 (acellular) demonstrated persistently greater UTS (40.5 ± 9.1 vs. 14.6 ± 4.2 MPa, ptendons that were decellularized with SDS, EDTA, and PAA resulted in removal of cellular antigens and a decreased immune response when placed into Wistar

  15. The Science Training Program for Young Italian Physicists and Engineers at Fermilab

    Energy Technology Data Exchange (ETDEWEB)

    Barzi, Emanuela [Fermilab; Bellettini, Giorgio [INFN, Pisa; Donati, Simone [INFN, Pisa

    2015-03-12

    Since 1984 Fermilab has been hosting a two-month summer training program for selected undergraduate and graduate Italian students in physics and engineering. Building on the traditional close collaboration between the Italian National Institute of Nuclear Physics (INFN) and Fermilab, the program is supported by INFN, by the DOE and by the Scuola Superiore di Sant`Anna of Pisa (SSSA), and is run by the Cultural Association of Italians at Fermilab (CAIF). This year the University of Pisa has qualified it as a “University of Pisa Summer School”, and will grant successful students with European Supplementary Credits. Physics students join the Fermilab HEP research groups, while engineers join the Particle Physics, Accelerator, Technical, and Computing Divisions. Some students have also been sent to other U.S. laboratories and universities for special trainings. The programs cover topics of great interest for science and for social applications in general, like advanced computing, distributed data analysis, nanoelectronics, particle detectors for earth and space experiments, high precision mechanics, applied superconductivity. In the years, over 350 students have been trained and are now employed in the most diverse fields in Italy, Europe, and the U.S. In addition, the existing Laurea Program in Fermilab Technical Division was extended to the whole laboratory, with presently two students in Master’s thesis programs on neutrino physics and detectors in the Neutrino Division. And finally, a joint venture with the Italian Scientists and Scholars North-America Foundation (ISSNAF) provided this year 4 professional engineers free of charge for Fermilab. More details on all of the above can be found below.

  16. National Aeronautics and Space Administration (NASA)/american Society for Engineering Education (ASEE) Summer Faculty Fellowship Program, 1991, Volume 2

    Science.gov (United States)

    Hyman, William A. (Editor); Goldstein, Stanley H. (Editor)

    1991-01-01

    The objectives of the program are: (1) to further the professional knowledge of qualified engineering and science faculty members; (2) to stimulate an exchange of ideas between participants and NASA; (3) to enrich and refresh the research and teaching activities of participant's institutions; and (4) to contribute to the research objectives of the NASA Centers. A compilation of the final reports on the research projects done by the faculty fellows during the summer of 1991 are presented. Some of the topics covered include: collision avoidance for rover vehicles, bioinstrumentation, neural nets, total quality management of flexible space structures, project scheduling, nondestructive tests, orthostatic intolerance to bedrest, hypersonic reentry simulation, measuring human energy expenditure, tribological models, trace element movement in Anarctic ice, gastrointestinal function, and computer assisted instruction.

  17. Human Factors Engineering in Designing the Passengers' Cockpit of the Malaysian Commercial Suborbital Spaceplane

    Science.gov (United States)

    Ridzuan Zakaria, Norul; Mettauer, Adrian; Abu, Jalaluddin; Hassan, Mohd Roshdi; Ismail, Anwar Taufeek; Othman, Jamaluddin; Shaari, Che Zhuhaida; Nasron, Nasri

    2010-09-01

    The design of the passengers’ cabin or cockpit of commercial suborbital spaceplane is a new and exciting frontier in human factors engineering, which emphasizes on comfort and safety. There is a program to develop small piloted 3 seats commercial suborbital spaceplane by a group of Malaysians with their foreign partners, and being relatively small and due to its design philosophy, the spaceplane does not require a cabin, but only a cockpit for its 2 passengers. In designing the cockpit, human factors engineering and safety principles are given priority. The cockpit is designed with the intention to provide comfort and satisfaction to the passengers without compromising the safety, in such a way that there are passenger-view wide angled video camera to observe the passengers at all time in flight, “rear-view”, “under-the-floor-view” and “fuselage-view” video cameras for the passengers, personalized gauges and LCDs on the dashboard to provide vital and useful information during the flight to the passengers, and biomedical engineered products which not only entertain the passengers, but also provide important information on the passengers to the ground crews who are responsible in the comfort and safety of the passengers. The passenger-view video-camera, which record the passengers with Earth visible through the glass canopy as the background, not only provides live visual of the passengers for safety reason, but also provide the most preferred memorable video collection for the passengers, while other video cameras provide the opportunity to view at various angles from unique positions to both the passengers and the ground observers. The gauges and LCDs on the dashboard provide access to the passengers to information such as the gravity, orientation, rate of climb and flight profile of the spaceplane, graphical presentation of the spaceplane in flight, and live video from the onboard video cameras. There is also a control stick for each passenger to

  18. Closed-Cycle Engine Program Used to Study Brayton Power Conversion

    Science.gov (United States)

    Johnson, Paul K.

    2005-01-01

    One form of power conversion under consideration in NASA Glenn Research Center's Thermal Energy Conversion Branch is the closed-Brayton-cycle engine. In the tens-of-kilowatts to multimegawatt class, the Brayton engine lends itself to potential space nuclear power applications such as electric propulsion or surface power. The Thermal Energy Conversion Branch has most recently concentrated its Brayton studies on electric propulsion for Prometheus. One piece of software used for evaluating such designs over a limited tradeoff space has been the Closed Cycle Engine Program (CCEP). The CCEP originated in the mid-1980s from a Fortran aircraft engine code known as the Navy/NASA Engine Program (NNEP). Components such as a solar collector, heat exchangers, ducting, a pumped-loop radiator, a nuclear heat source, and radial turbomachinery were added to NNEP, transforming it into a high-fidelity design and performance tool for closed-Brayton-cycle power conversion and heat rejection. CCEP was used in the 1990s in conjunction with the Solar Dynamic Ground Test Demonstration conducted at Glenn. Over the past year, updates were made to CCEP to adapt it for an electric propulsion application. The pumped-loop radiator coolant can now be n-heptane, water, or sodium-potassium (NaK); liquid-metal pump design tables were added to accommodate the NaK fluid. For the reactor and shield, a user can now elect to calculate a higher fidelity mass estimate. In addition, helium-xenon working-fluid properties were recalculated and updated.

  19. Department of Energy Programmatic Spent Nuclear Fuel Management and Idaho National Engineering Laboratory Environmental Restoration and Waste Management Programs draft environmental impact statement. Volume 1, Appendix B: Idaho National Engineering Laboratory Spent Nuclear Fuel Management Program

    Energy Technology Data Exchange (ETDEWEB)

    1994-06-01

    The US Department of Energy (DOE) has prepared this report to assist its management in making two decisions. The first decision, which is programmatic, is to determine the management program for DOE spent nuclear fuel. The second decision is on the future direction of environmental restoration, waste management, and spent nuclear fuel management activities at the Idaho National Engineering Laboratory. Volume 1 of the EIS, which supports the programmatic decision, considers the effects of spent nuclear fuel management on the quality of the human and natural environment for planning years 1995 through 2035. DOE has derived the information and analysis results in Volume 1 from several site-specific appendixes. Volume 2 of the EIS, which supports the INEL-specific decision, describes environmental impacts for various environmental restoration, waste management, and spent nuclear fuel management alternatives for planning years 1995 through 2005. This Appendix B to Volume 1 considers the impacts on the INEL environment of the implementation of various DOE-wide spent nuclear fuel management alternatives. The Naval Nuclear Propulsion Program, which is a joint Navy/DOE program, is responsible for spent naval nuclear fuel examination at the INEL. For this appendix, naval fuel that has been examined at the Naval Reactors Facility and turned over to DOE for storage is termed naval-type fuel. This appendix evaluates the management of DOE spent nuclear fuel including naval-type fuel.

  20. HFE (Human Factors Engineering) Technology for Navy Weapon System Acquisition.

    Science.gov (United States)

    1979-07-01

    uncovering of improved propulsion systems, sensors , weapons, etc., by industry or governr-ient agencies, may in.tiate the development of a new weapon system...needs. (No. A-109) _L a f. Tailor an acquisition stratagy for each program, as soon as the agency decides to solict alternative system design concepto

  1. Integrating the human element into the systems engineering process and MBSE methodology.

    Energy Technology Data Exchange (ETDEWEB)

    Tadros, Michael Samir.

    2013-12-01

    In response to the challenges related to the increasing size and complexity of systems, organizations have recognized the need to integrate human considerations in the beginning stages of systems development. Human Systems Integration (HSI) seeks to accomplish this objective by incorporating human factors within systems engineering (SE) processes and methodologies, which is the focus of this paper. A representative set of HSI methods from multiple sources are organized, analyzed, and mapped to the systems engineering Vee-model. These methods are then consolidated and evaluated against the SE process and Models-Based Systems Engineering (MBSE) methodology to determine where and how they could integrate within systems development activities in the form of specific enhancements. Overall conclusions based on these evaluations are presented and future research areas are proposed.

  2. Effects of mechanical loading on human mesenchymal stem cells for cartilage tissue engineering.

    Science.gov (United States)

    Choi, Jane Ru; Yong, Kar Wey; Choi, Jean Yu

    2017-05-19

    Today, articular cartilage damage is a major health problem, affecting people of all ages. The existing conventional articular cartilage repair techniques, such as autologous chondrocyte implantation (ACI), microfracture, and mosaicplasty, have many shortcomings which negatively affect their clinical outcomes. Therefore, it is essential to develop an alternative and efficient articular repair technique that can address those shortcomings. Cartilage tissue engineering, which aims to create a tissue-engineered cartilage derived from human mesenchymal stem cells (MSCs), shows great promise for improving articular cartilage defect therapy. However, the use of tissue-engineered cartilage for the clinical therapy of articular cartilage defect still remains challenging. Despite the importance of mechanical loading to create a functional cartilage has been well demonstrated, the specific type of mechanical loading and its optimal loading regime is still under investigation. This review summarizes the most recent advances in the effects of mechanical loading on human MSCs. First, the existing conventional articular repair techniques and their shortcomings are highlighted. The important parameters for the evaluation of the tissue-engineered cartilage, including chondrogenic and hypertrophic differentiation of human MSCs are briefly discussed. The influence of mechanical loading on human MSCs is subsequently reviewed and the possible mechanotransduction signaling is highlighted. The development of non-hypertrophic chondrogenesis in response to the changing mechanical microenvironment will aid in the establishment of a tissue-engineered cartilage for efficient articular cartilage repair. © 2017 Wiley Periodicals, Inc.

  3. Engineered Microenvironments for the Maturation and Observation of Human Embryonic Stem Cell Derived Cardiomyocytes

    Science.gov (United States)

    Salick, Max R.

    The human heart is a dynamic system that undergoes substantial changes as it develops and adapts to the body's growing needs. To better understand the physiology of the heart, researchers have begun to produce immature heart muscle cells, or cardiomyocytes, from pluripotent stem cell sources with remarkable efficiency. These stem cell-derived cardiomyocytes hold great potential in the understanding and treatment of heart disease; however, even after prolonged culture, these cells continue to exhibit an immature phenotype, as indicated by poor sarcomere organization and calcium handling, among other features. The lack of maturation that is observed in these cardiomyocytes greatly limits their applicability towards drug screening, disease modeling, and cell therapy applications. The mechanical environment surrounding a cell has been repeatedly shown to have a large impact on that cell's behavior. For this reason, we have implemented micropatterning methods to mimic the level of alignment that occurs in the heart in vivo in order to study how this alignment may help the cells to produce a more mature sarcomere phenotype. It was discovered that the level of sarcomere organization of a cardiomyocyte can be strongly influenced by the micropattern lane geometry on which it adheres. Steps were taken to optimize this micropattern platform, and studies of protein organization, gene expression, and myofibrillogenesis were conducted. Additionally, a set of programs was developed to provide quantitative analysis of the level of sarcomere organization, as well as to assist with several other tissue engineering applications.

  4. Designing Workshops for the Introduction of Lean Enablers to Engineering Programs

    DEFF Research Database (Denmark)

    Gersing, Kilian; Oehmen, Josef; Rebentisch, Eric Rebentisch

    2014-01-01

    There is a large and growing body of knowledge regarding so-called Lean best practices, including most recently in the area of program management and systems engineering. However, there is little elaboration of how these documented best practices are to be introduced to a professional workforce...... the systematic design of workshops focused specifically on the introduction of Lean principles and practices to program management and the professional workforce in a program environment. The framework is based on a thorough review of literature on training, workshop delivery, and Lean principles, as well...... the Lean principles. The framework was validated through interactions with training professionals in a large automobile manufacturer, and using subject matter experts from a variety of industrial sectors. © 2014 The Authors. Published by Elsevier B.V....

  5. Programming margin enlargement by material engineering for multilevel storage in phase-change memory

    Science.gov (United States)

    Yin, You; Noguchi, Tomoyuki; Ohno, Hiroki; Hosaka, Sumio

    2009-09-01

    In this work, we investigate the effect of the material engineering on programming margin in the double-layered phase-change memory, which is the most important parameter for the stability of multilevel storage. Compared with the TiN/SbTeN cell, the TiSiN/GeSbTe double-layered cell exhibits the resistance ratio of the highest to lowest resistance levels up to two to three orders of magnitude, indicating much larger programming margin and thus higher stability and/or more available levels. Our calculation results show that the resistivities of the top heating layer and the phase-change layer have a significant effect on the programming margin.

  6. Sodium sulfur electric vehicle battery engineering program final report, September 2, 1986--June 15, 1993

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1993-06-01

    In September 1986 a contract was signed between Chloride Silent Power Limited (CSPL) and Sandia National Laboratories (SNL) entitled ``Sodium Sulfur Electric Vehicle Battery Engineering Program``. The aim of the cost shared program was to advance the state of the art of sodium sulfur batteries for electric vehicle propulsion. Initially, the work statement was non-specific in regard to the vehicle to be used as the design and test platform. Under a separate contract with the DOE, Ford Motor Company was designing an advanced electric vehicle drive system. This program, called the ETX II, used a modified Aerostar van for its platform. In 1987, the ETX II vehicle was adopted for the purposes of this contract. This report details the development and testing of a series of battery designs and concepts which led to the testing, in the US, of three substantial battery deliverables.

  7. Human Cardiac Tissue Engineering: From Pluripotent Stem Cells to Heart Repair

    Science.gov (United States)

    Jackman, Christopher P.; Shadrin, Ilya Y.; Carlson, Aaron L.; Bursac, Nenad

    2014-01-01

    Engineered cardiac tissues hold great promise for use in drug and toxicology screening, in vitro studies of human physiology and disease, and as transplantable tissue grafts for myocardial repair. In this review, we discuss recent progress in cell-based therapy and functional tissue engineering using pluripotent stem cell-derived cardiomyocytes and we describe methods for delivery of cells into the injured heart. While significant hurdles remain, notable advances have been made in the methods to derive large numbers of pure human cardiomyocytes, mature their phenotype, and produce and implant functional cardiac tissues, bringing the field a step closer to widespread in vitro and in vivo applications. PMID:25599018

  8. A Virtual Campus Based on Human Factor Engineering

    Science.gov (United States)

    Yang, Yuting; Kang, Houliang

    2014-01-01

    Three Dimensional or 3D virtual reality has become increasingly popular in many areas, especially in building a digital campus. This paper introduces a virtual campus, which is based on a 3D model of The Tourism and Culture College of Yunnan University (TCYU). Production of the virtual campus was aided by Human Factor and Ergonomics (HF&E), an…

  9. A Virtual Campus Based on Human Factor Engineering

    Science.gov (United States)

    Yang, Yuting; Kang, Houliang

    2014-01-01

    Three Dimensional or 3D virtual reality has become increasingly popular in many areas, especially in building a digital campus. This paper introduces a virtual campus, which is based on a 3D model of The Tourism and Culture College of Yunnan University (TCYU). Production of the virtual campus was aided by Human Factor and Ergonomics (HF&E), an…

  10. Engineering Data Compendium. Human Perception and Performance. Volume 3

    Science.gov (United States)

    1988-01-01

    Breitmeyer, B. G. (1975). Sim- cies to sinusoidal gratings. Vision human observers: A probabilistic pie reaction time as a measure of Research. 16...oscilloscope; viewed at optical infinity through a plano - convex lens (153 mm diameter, 340 mm focal length) one focal length from display • Patch wom

  11. A Paperless Course on Structural Engineering Programming: Investing in Educational Technology in the Times of the Greek Financial Recession

    Science.gov (United States)

    Sextos, Anastasios G.

    2014-01-01

    This paper presents the structure of an undergraduate course entitled "programming techniques and the use of specialised software in structural engineering" which is offered to the fifth (final) year students of the Civil Engineering Department of Aristotle University Thessaloniki in Greece. The aim of this course is to demonstrate the…

  12. Engineering targeted chromosomal amplifications in human breast epithelial cells.

    Science.gov (United States)

    Springer, Simeon; Yi, Kyung H; Park, Jeenah; Rajpurohit, Anandita; Price, Amanda J; Lauring, Josh

    2015-07-01

    Chromosomal amplifications are among the most common genetic alterations found in human cancers. However, experimental systems to study the processes that lead to specific, recurrent amplification events in human cancers are lacking. Moreover, some common amplifications, such as that at 8p11-12 in breast cancer, harbor multiple driver oncogenes, which are poorly modeled by conventional overexpression approaches. We sought to develop an experimental system to model recurrent chromosomal amplification events in human cell lines. Our strategy is to use homologous-recombination-mediated gene targeting to deliver a dominantly selectable, amplifiable marker to a specified chromosomal location. We used adeno-associated virus vectors to target human MCF-7 breast cancer cells at the ZNF703 locus, in the recurrent 8p11-12 amplicon, using the E. coli inosine monophosphate dehydrogenase (IMPDH) enzyme as a marker. We applied selective pressure using IMPDH inhibitors. Surviving clones were found to have increased copy number of ZNF703 (average 2.5-fold increase) by droplet digital PCR and FISH. Genome-wide array comparative genomic hybridization confirmed that amplifications had occurred on the short arm of chromosome 8, without changes on 8q or other chromosomes. Patterns of amplification were variable and similar to those seen in primary human breast cancers, including "sawtooth" patterns, distal copy number loss, and large continuous regions of copy number gain. This system will allow study of the cis- and trans-acting factors that are permissive for chromosomal amplification and provide a model to analyze oncogene cooperativity in amplifications harboring multiple candidate driver genes.

  13. Rate-programming of nano-particulate delivery systems for smart bioactive scaffolds in tissue engineering

    Science.gov (United States)

    Izadifar, Mohammad; Haddadi, Azita; Chen, Xiongbiao; Kelly, Michael E.

    2015-01-01

    Development of smart bioactive scaffolds is of importance in tissue engineering, where cell proliferation, differentiation and migration within scaffolds can be regulated by the interactions between cells and scaffold through the use of growth factors (GFs) and extra cellular matrix peptides. One challenge in this area is to spatiotemporally control the dose, sequence and profile of release of GFs so as to regulate cellular fates during tissue regeneration. This challenge would be addressed by rate-programming of nano-particulate delivery systems, where the release of GFs via polymeric nanoparticles is controlled by means of the methods of, such as externally-controlled and physicochemically/architecturally-modulated so as to mimic the profile of physiological GFs. Identifying and understanding such factors as the desired release profiles, mechanisms of release, physicochemical characteristics of polymeric nanoparticles, and externally-triggering stimuli are essential for designing and optimizing such delivery systems. This review surveys the recent studies on the desired release profiles of GFs in various tissue engineering applications, elucidates the major release mechanisms and critical factors affecting release profiles, and overviews the role played by the mathematical models for optimizing nano-particulate delivery systems. Potentials of stimuli responsive nanoparticles for spatiotemporal control of GF release are also presented, along with the recent advances in strategies for spatiotemporal control of GF delivery within tissue engineered scaffolds. The recommendation for the future studies to overcome challenges for developing sophisticated particulate delivery systems in tissue engineering is discussed prior to the presentation of conclusions drawn from this paper.

  14. Rate-programming of nano-particulate delivery systems for smart bioactive scaffolds in tissue engineering.

    Science.gov (United States)

    Izadifar, Mohammad; Haddadi, Azita; Chen, Xiongbiao; Kelly, Michael E

    2015-01-09

    Development of smart bioactive scaffolds is of importance in tissue engineering, where cell proliferation, differentiation and migration within scaffolds can be regulated by the interactions between cells and scaffold through the use of growth factors (GFs) and extra cellular matrix peptides. One challenge in this area is to spatiotemporally control the dose, sequence and profile of release of GFs so as to regulate cellular fates during tissue regeneration. This challenge would be addressed by rate-programming of nano-particulate delivery systems, where the release of GFs via polymeric nanoparticles is controlled by means of the methods of, such as externally-controlled and physicochemically/architecturally-modulated so as to mimic the profile of physiological GFs. Identifying and understanding such factors as the desired release profiles, mechanisms of release, physicochemical characteristics of polymeric nanoparticles, and externally-triggering stimuli are essential for designing and optimizing such delivery systems. This review surveys the recent studies on the desired release profiles of GFs in various tissue engineering applications, elucidates the major release mechanisms and critical factors affecting release profiles, and overviews the role played by the mathematical models for optimizing nano-particulate delivery systems. Potentials of stimuli responsive nanoparticles for spatiotemporal control of GF release are also presented, along with the recent advances in strategies for spatiotemporal control of GF delivery within tissue engineered scaffolds. The recommendation for the future studies to overcome challenges for developing sophisticated particulate delivery systems in tissue engineering is discussed prior to the presentation of conclusions drawn from this paper.

  15. Mobile Robots in Teaching Programming for IT Engineers and its Effects

    Directory of Open Access Journals (Sweden)

    Attila Pásztor

    2013-12-01

    Full Text Available in this paper the new methods and devices introduced into the learning process of programming for IT engineers at our college is described. Based on our previous research results we supposed that project methods and some new devices can reduce programming problems during the first term. These problems are rooted in the difficulties of abstract thinking and they can cause the decrease of programming self-concept and other learning motives. We redesigned the traditional learning environment. As a constructive approach project method was used. Our students worked in groups of two or three; small problems were solved after every lesson. In the problem solving process students use programmable robots (e.g. Surveyor, LEGO NXT and RCX. They had to plan their program, solve some technical problems and test their solution. The usability of mobile robots in the learning process and the short-term efficiency of our teaching method were checked with a control group after a semester (n = 149. We examined the effects on our students’ programming skills and on their motives, mainly on their attitudes and programming self-concept. After a two-year-long period we could measure some positive long-term effects.

  16. Using Fuzzy Gaussian Inference and Genetic Programming to Classify 3D Human Motions

    Science.gov (United States)

    Khoury, Mehdi; Liu, Honghai

    This research introduces and builds on the concept of Fuzzy Gaussian Inference (FGI) (Khoury and Liu in Proceedings of UKCI, 2008 and IEEE Workshop on Robotic Intelligence in Informationally Structured Space (RiiSS 2009), 2009) as a novel way to build Fuzzy Membership Functions that map to hidden Probability Distributions underlying human motions. This method is now combined with a Genetic Programming Fuzzy rule-based system in order to classify boxing moves from natural human Motion Capture data. In this experiment, FGI alone is able to recognise seven different boxing stances simultaneously with an accuracy superior to a GMM-based classifier. Results seem to indicate that adding an evolutionary Fuzzy Inference Engine on top of FGI improves the accuracy of the classifier in a consistent way.

  17. A Review on the Regulatory Strategy of Human Factors Engineering Consideration in Pakistan Nuclear Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Sohail, Sabir [Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of); Choi, Seong Nam [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2013-10-15

    In this paper, the legal and regulatory infrastructure available in Pakistan for HFE requirements is assessed, and the methodology for strengthening of legal infrastructure is presented. The regulatory strategy on evaluation of HFE consideration should provide reviewers with guidance on review process. Therefore, the suggested methodology is based on preparation of guidance documents such as checklist, working procedures, S and Gs etc.; incorporation of PRM elements in regulatory system; and finally the development of PRM implementation criteria. Altogether, the scheme provide the enhancement in regulatory infrastructure and also the effective and efficient review process. The Three Mile Island (TMI) accident brought the general consensus among the nuclear community on the integration of human factors engineering (HFE) principles in all phases of nuclear power. This notion has further strengthened after the recent Fukushima nuclear accident. Much effort has been put over to incorporate the lesson learned and continuous technical evolution on HFE to device different standards. The total of 174 ergonomics standards are alone identified by Dul et al. (2004) published by International Organization for Standardization (ISO) and the European Committee for Standardization (CEN) and number of standards and HFE guidelines (S and Gs) are also published by organizations like Institute for Electrical and Electronics Engineering (IEEE), International Electrotechnical Commission (IEC), International Atomic Energy Agency (IAEA), United States Nuclear Regulatory Commission (USNRC), etc. The ambition of effective review on HFE integration in nuclear facility might be accomplished through the development of methodology for systematic implementation of S and Gs. Such kind of methodology would also be beneficial for strengthening the regulatory framework and practices for countries new in the nuclear arena and with small scale nuclear program. The objective of paper is to review the

  18. A comparative analysis of reading strategies across ESP students of humanities and engineering

    Directory of Open Access Journals (Sweden)

    Mehdi Vaez Dalili

    2013-04-01

    Full Text Available This study set out to explore whether significant differences existed between two groups of EFL students of different fields of study (i.e. humanities and engineering in terms of their metacognitive awareness and use of certain reading strategies while reading English for Specific Purposes (ESP texts. Seventy lower-intermediate college-level students (35 engineering students and 35 students of humanities completed the Metacognitive Awareness of Reading Strategies Inventory (Mokhtari & Reichard, 2002 to measure their metacognitive awareness of ESP reading strategies. The inventory includes 3 strategy subscales with 30 items: Global Reading Strategies (GLOB, Problem-Solving Strategies (PROB, and Support Reading Strategies (SUP. A series of t-tests were conducted to figure out the differences between the two groups of students in connection with each of the strategies in the MARSI inventory. The results showed that in spite of the fact that the two groups were studying different fields of study, they reported strikingly similar patterns of reading strategy awareness and confirmed having used almost all of the strategies while reading ESP materials. However, the engineering students reported using some types of reading strategies more frequently than did the humanities students. The findings of the study will not only explain the differences and similarities between engineering and humanities students, but also help to challenge the purely speculative assumption as to the deficiencies in strategy-based ESP reading comprehension of humanities students.

  19. Engineered human broncho-epithelial tissue-like assemblies

    Science.gov (United States)

    Goodwin, Thomas J. (Inventor)

    2012-01-01

    Three-dimensional human broncho-epithelial tissue-like assemblies (TLAs) are produced in a rotating wall vessel (RWV) with microcarriers by coculturing mesenchymal bronchial-tracheal cells (BTC) and bronchial epithelium cells (BEC). These TLAs display structural characteristics and express markers of in vivo respiratory epithelia. TLAs are useful for screening compounds active in lung tissues such as antiviral compounds, cystic fibrosis treatments, allergens, and cytotoxic compounds.

  20. Primer on Molecular Genetics; DOE Human Genome Program

    Science.gov (United States)

    1992-04-01

    This report is taken from the April 1992 draft of the DOE Human Genome 1991--1992 Program Report, which is expected to be published in May 1992. The primer is intended to be an introduction to basic principles of molecular genetics pertaining to the genome project. The material contained herein is not final and may be incomplete. Techniques of genetic mapping and DNA sequencing are described.