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Sample records for hr mas technique

  1. {sup 1}H HR-MAS NMR and S180 cells: metabolite assignment and evaluation of pulse sequence

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Aline L. de; Martinelli, Bruno César B.; Lião, Luciano M. [Universidade Federal de Goiás (UFG), Goiânia, GO (Brazil). Instituto de Química. Lab. de RMN; Pereira, Flávia C.; Silveira-Lacerda, Elisangela P. [Universidade Federal de Goiás (UFG), Goiânia, GO (Brazil). Instituto de Ciências Biológicas. Laboratório Genética Molecular e Citogenética; Alcantara, Glaucia B., E-mail: glaucia.alcantara@ufms.br [Universidade Federal de Mato Grosso do Sul (UFMS), Campo Grande, MS (Brazil). Inst. de Química

    2014-07-01

    High resolution magic angle spinning {sup 1}H nuclear magnetic resonance spectroscopy (HR-MAS NMR) is a useful technique for evaluation of intact cells and tissues. However, optimal NMR parameters are crucial in obtaining reliable results. To identify the key steps for the optimization of HR-MAS NMR parameters, we assessed different pulse sequences and NMR parameters using sarcoma 180 (S180) cells. A complete assignment of the metabolites of S180 is given to assist future studies. (author)

  2. 1H HR-MAS NMR and S180 cells: metabolite assignment and evaluation of pulse sequence

    International Nuclear Information System (INIS)

    Oliveira, Aline L. de; Martinelli, Bruno César B.; Lião, Luciano M.; Pereira, Flávia C.; Silveira-Lacerda, Elisangela P.; Alcantara, Glaucia B.

    2014-01-01

    High resolution magic angle spinning 1 H nuclear magnetic resonance spectroscopy (HR-MAS NMR) is a useful technique for evaluation of intact cells and tissues. However, optimal NMR parameters are crucial in obtaining reliable results. To identify the key steps for the optimization of HR-MAS NMR parameters, we assessed different pulse sequences and NMR parameters using sarcoma 180 (S180) cells. A complete assignment of the metabolites of S180 is given to assist future studies. (author)

  3. HR-MAS NMR allied to chemometric on Hancornia speciosa varieties differentiation

    Energy Technology Data Exchange (ETDEWEB)

    Flores, Igor S. [Instituto Federal de Goiás (IFG), Luziânia, GO (Brazil); Silva, Andressa K.; Chaves, Lazaro J.; Collevatti, Rosane G.; Lião, Luciano M., E-mail: lucianoliao@ufg.br [Universidade Federal de Goiás (UFG), Goiânia, GO (Brazil); Furquim, Leonnardo C. [Faculdade Objetivo, GO (Brazil); Castro, Carlos F.S. [Instituto Federal de Educação, Ciência e Tecnologia Goiano (IFGoiano), GO (Brazil)

    2018-05-01

    This work describes the potential of chemometric analyses applied to {sup 1}H high-resolution magic angle spinning nuclear magnetic resonance ({sup 1}H HR-MAS NMR) data for the chemotaxonomic investigation of Hancornia speciosa (Apocynaceae) varieties. This plant, popularly known as mangaba, has a complex morphological differentiation and thus chemical analyses can be used for their taxonomic classification. In comparison to traditional techniques, {sup 1}H HR-MAS NMR allied with chemometrics provided a simple and low cost method for chemotaxonomy. Leaves of four varieties of H. speciosa from a common garden experiment was studied and demonstrated that H. speciosa var. speciosa differs from others due to its specific metabolic profile, and var. pubescens was discriminated based on its high phenolic compound content. The distinction between the latter variety and gardineri is important once it allows for the selection of samples with greater commercial value, once they produce the largest and heaviest fruits. (author)

  4. Chemical profile of beans cultivars (Phaseolus vulgaris) by 1H NMR - high resolution magic angle spinning (HR-MAS);Perfil quimico de cultivares de feijao (Phaseolus vulgaris) pela tecnica de high resolution magic angle spinning (HR-MAS)

    Energy Technology Data Exchange (ETDEWEB)

    Liao, Luciano Morais; Choze, Rafael; Cavalcante, Pedro Paulo Araujo; Santos, Suzana da Costa; Ferri, Pedro Henrique, E-mail: luciano@quimica.ufg.b [Universidade Federal de Goias (UFG), Goiania, GO (Brazil). Inst. de Quimica; Ferreira, Antonio Gilberto [Universidade Federal de Sao Carlos (UFScar), SP (Brazil). Dept. de Quimica

    2010-07-01

    The application of one-dimensional proton high-resolution magic angle spinning ({sup 1}H HR-MAS) NMR combined with a typical advantages of solid and liquid-state NMR techniques was used as input variables for the multivariate statistical analysis. In this paper, different cultivars of beans (Phaseolus vulgaris) developed and in development by EMBRAPA - Arroz e Feijao were analyzed by {sup 1}H HR-MAS, which have been demonstrated to be a valuable tool in its differentiation according chemical composition and avoid the manipulation of the samples as used in other techniques. (author)

  5. HR-MAS NMR for rapid identification of illicit substances in tablets and Blotter papers seized by Police Department

    Energy Technology Data Exchange (ETDEWEB)

    Souza, Luciano F.; Vieira, Tarcísio S.; Lião, Luciano M., E-mail: lucianoliao@ufg.br [Universidade Federal de Goiás (UFG), Goiânia, GO (Brazil). Instituto de Química; Alcantara, Glaucia B. [Universidade Federal de Mato Grosso do Sul (UFMS), Campo Grande, MS (Brazil). Instituto de Química

    2016-07-01

    Illicit substances found in blotter papers and tablets seized by police are traditionally identified and characterized from extracts of these materials. However, the procedures involved in extraction stages can result in artifacts and even contamination of the samples to be analyzed. On the other hand, high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) is a technique that requires no pretreatment steps, enabling direct analysis of the material, including the analysis of new illegal synthetic psychoactive substances. This study presents and discusses applications of the HR-MAS NMR in the analysis of tablets and blotter papers seized. Additional analysis in solution of the extracts of these materials was performed to compare the obtained spectral resolution signals. The results demonstrated that the HR-MAS NMR allowed the rapid identification of 3,4-methylenedioxy-N-methylcathinone (methylone), 4-methylmethcathinone (mephedrone), 2,5-dimethoxy-4-bromoamphetamine (DOB) and 2-(4-bromo-2,5-dimethoxyphenyl)-N-[(2- methoxyphenyl)methyl]ethanamine (25B-NBOMe) in samples of tablets and blotter papers seized in Goiás State, Brazil. (author)

  6. HR-MAS NMR for rapid identification of illicit substances in tablets and Blotter papers seized by Police Department

    International Nuclear Information System (INIS)

    Souza, Luciano F.; Vieira, Tarcísio S.; Lião, Luciano M.; Alcantara, Glaucia B.

    2016-01-01

    Illicit substances found in blotter papers and tablets seized by police are traditionally identified and characterized from extracts of these materials. However, the procedures involved in extraction stages can result in artifacts and even contamination of the samples to be analyzed. On the other hand, high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) is a technique that requires no pretreatment steps, enabling direct analysis of the material, including the analysis of new illegal synthetic psychoactive substances. This study presents and discusses applications of the HR-MAS NMR in the analysis of tablets and blotter papers seized. Additional analysis in solution of the extracts of these materials was performed to compare the obtained spectral resolution signals. The results demonstrated that the HR-MAS NMR allowed the rapid identification of 3,4-methylenedioxy-N-methylcathinone (methylone), 4-methylmethcathinone (mephedrone), 2,5-dimethoxy-4-bromoamphetamine (DOB) and 2-(4-bromo-2,5-dimethoxyphenyl)-N-[(2- methoxyphenyl)methyl]ethanamine (25B-NBOMe) in samples of tablets and blotter papers seized in Goiás State, Brazil. (author)

  7. 1H HR-MAS NMR Spectroscopy and the Metabolite Determination of Typical Foods in Mediterranean Diet

    Directory of Open Access Journals (Sweden)

    Carmelo Corsaro

    2015-01-01

    Full Text Available NMR spectroscopy has become an experimental technique widely used in food science. The experimental procedures that allow precise and quantitative analysis on different foods are relatively simple. For a better sensitivity and resolution, NMR spectroscopy is usually applied to liquid sample by means of extraction procedures that can be addressed to the observation of particular compounds. For the study of semisolid systems such as intact tissues, High-Resolution Magic Angle Spinning (HR-MAS has received great attention within the biomedical area and beyond. Metabolic profiling and metabolism changes can be investigated both in animal organs and in foods. In this work we present a proton HR-MAS NMR study on the typical vegetable foods of Mediterranean diet such as the Protected Geographical Indication (PGI cherry tomato of Pachino, the PGI Interdonato lemon of Messina, several Protected Designation of Origin (PDO extra virgin olive oils from Sicily, and the Traditional Italian Food Product (PAT red garlic of Nubia. We were able to identify and quantify the main metabolites within the studied systems that can be used for their characterization and authentication.

  8. Assessing Heterogeneity of Osteolytic Lesions in Multiple Myeloma by 1H HR-MAS NMR Metabolomics

    Directory of Open Access Journals (Sweden)

    Laurette Tavel

    2016-10-01

    Full Text Available Multiple myeloma (MM is a malignancy of plasma cells characterized by multifocal osteolytic bone lesions. Macroscopic and genetic heterogeneity has been documented within MM lesions. Understanding the bases of such heterogeneity may unveil relevant features of MM pathobiology. To this aim, we deployed unbiased 1H high-resolution magic-angle spinning (HR-MAS nuclear magnetic resonance (NMR metabolomics to analyze multiple biopsy specimens of osteolytic lesions from one case of pathological fracture caused by MM. Multivariate analyses on normalized metabolite peak integrals allowed clusterization of samples in accordance with a posteriori histological findings. We investigated the relationship between morphological and NMR features by merging morphological data and metabolite profiling into a single correlation matrix. Data-merging addressed tissue heterogeneity, and greatly facilitated the mapping of lesions and nearby healthy tissues. Our proof-of-principle study reveals integrated metabolomics and histomorphology as a promising approach for the targeted study of osteolytic lesions.

  9. Exploring high-resolution magic angle spinning (HR-MAS) NMR spectroscopy for metabonomic analysis of apples.

    Science.gov (United States)

    Vermathen, Martina; Marzorati, Mattia; Vermathen, Peter

    2012-01-01

    Classical liquid-state high-resolution (HR) NMR spectroscopy has proved a powerful tool in the metabonomic analysis of liquid food samples like fruit juices. In this paper the application of (1)H high-resolution magic angle spinning (HR-MAS) NMR spectroscopy to apple tissue is presented probing its potential for metabonomic studies. The (1)H HR-MAS NMR spectra are discussed in terms of the chemical composition of apple tissue and compared to liquid-state NMR spectra of apple juice. Differences indicate that specific metabolic changes are induced by juice preparation. The feasibility of HR-MAS NMR-based multivariate analysis is demonstrated by a study distinguishing three different apple cultivars by principal component analysis (PCA). Preliminary results are shown from subsequent studies comparing three different cultivation methods by means of PCA and partial least squares discriminant analysis (PLS-DA) of the HR-MAS NMR data. The compounds responsible for discriminating organically grown apples are discussed. Finally, an outlook of our ongoing work is given including a longitudinal study on apples.

  10. PLEIADES-HR INNOVATIVE TECHNIQUES FOR RADIOMETRIC IMAGE QUALITY COMMISSIONING

    Directory of Open Access Journals (Sweden)

    G. Blanchet

    2012-07-01

    Full Text Available The first Pleiades-HR satellite, part of a constellation of two, has been launched on December 17, 2011. This satellite produces high resolution optical images. In order to achieve good image quality, Pleiades-HR should first undergo an important 6 month commissioning phase period. This phase consists in calibrating and assessing the radiometric and geometric image quality to offer the best images to end users. This new satellite has benefited from technology improvements in various fields which make it stand out from other Earth observation satellites. In particular, its best-in-class agility performance enables new calibration and assessment techniques. This paper is dedicated to presenting these innovative techniques that have been tested for the first time for the Pleiades- HR radiometric commissioning. Radiometric activities concern compression, absolute calibration, detector normalization, and refocusing operations, MTF (Modulation Transfer Function assessment, signal-to-noise ratio (SNR estimation, and tuning of the ground processing parameters. The radiometric performances of each activity are summarized in this paper.

  11. RESTORATION TECHNIQUE FOR PLEIADES-HR PANCHROMATIC IMAGES

    Directory of Open Access Journals (Sweden)

    C. Latry

    2012-07-01

    Full Text Available 17th of December 2011 from Kourou Space Centre, French Guyana. Like others high resolution optical satellites, it acquires both panchromatic images, with 70cm spatial resolution, and lower resolution multispectral images with 2.8m spatial resolution. Pleiades-HR is an optimized system, which means that the Modulation Transfer Function has a low value at Nyquist frequency, in order to reduce both the telescope diameter and aliasing effects. Shannon sampling condition is thus met at first order, which also makes classical ground processing, such as image matching or resampling, more justified for a mathematical point of view. Raw images are thus blurry which implies a deconvolution stage that restores sharpness but also increases the noise level in the high frequency domain. A denoising step, based upon wavelet packet coefficients thresholding/shrinkage technique, allows controlling the final noise level. Each of these methods includes numerous parameters that have to be assessed during the inflight commissioning period: deconvolution filter that depends on MTF assessment, instrumental noise model, noise level target for denoised images, wavelet packet decomposition level. This paper aims to precisely describe the deconvolution/denoising algorithms and how their main parameters have been set up during the inflight commissioning stage. Special attention will be given to structured noise induced by Pleiades-HR on board wavelet-based compression algorithm

  12. Two-Stage MAS Technique for Analysis of DRA Elements and Arrays on Finite Ground Planes

    DEFF Research Database (Denmark)

    Larsen, Niels Vesterdal; Breinbjerg, Olav

    2007-01-01

    A two-stage Method of Auxiliary Sources (MAS) technique is proposed for analysis of dielectric resonator antenna (DRA) elements and arrays on finite ground planes (FGPs). The problem is solved by first analysing the DRA on an infinite ground plane (IGP) and then using this solution to model the FGP...

  13. PLEIADES-HR INNOVATIVE TECHNIQUES FOR GEOMETRIC IMAGE QUALITY COMMISSIONING

    Directory of Open Access Journals (Sweden)

    D. Greslou

    2012-07-01

    Full Text Available Since the beginning of 2012, the first Pleiades-HR satellite of the program conducted by the French National Space Agency, CNES, delivers 20 km wide color scenes with a 70 cm ground sampling distance. A second satellite should be launched in 2013 which will achieve an almost world-wide coverage with a revisit interval of 24h. The assessment of the image quality and the calibration operation have been performed by CNES Image Quality team during the 6 month commissioning phase that followed the satellite launch. The geometric commissioning activities consist in improve the geometric quality of the images in order to meet very demanding specifications as localization accuracy, local coherence, dynamic stability, length alteration … This goal has been achieved through the implementation of new methods of calibration and performance assessment. Some of these methods are based on the exploitation of very specific satellite acquisitions that have been achieved thanks to the amazing agility of the Pleiades satellite. Thus, many stars acquisitions and very slow earth pictures have been processed to characterize dynamic phenomena. Similarly, “along-cross track” pairs have been exploited to improve the accuracy of the focal plane description. This paper deals with these new methods. It describes their accuracy and their operational interests.

  14. Caretakers or HR Managers

    Directory of Open Access Journals (Sweden)

    James Baba Abugre

    2014-08-01

    Full Text Available Do human resources (HR managers in developing countries have the clout to make strategic decisions during mergers and acquisitions (M&As? This study aims at establishing the major roles played by HR managers in M&As of public sector companies in Ghana. The research examined the M&As of 10 Ghanaian companies where 10 HR managers gave detailed narratives of their roles and the part they played in the M&A processes. The qualitative method used to solicit the narratives of the HR managers resulted in the following findings: that HR managers in Ghana have a limited role in the planning process of the M&A; that indigenous HR managers perform several tasks in the course of the M&A to get employees stable before and after the M&A processes; nevertheless, they are not part of the policy formulators. The article makes a modest input of the significance of indigenous HR role in international M&As as a panacea to solving the global crises by advocating the empowerment of HR managers in developing context to be partners in the initial commencement of M&As.

  15. HR Connect

    Data.gov (United States)

    US Agency for International Development — HR Connect is the USAID HR personnel system which allows HR professionals to process HR actions related to employee's personal and position information. This system...

  16. 1H MAS NMR (magic-angle spinning nuclear magnetic resonance) techniques for the quantitative determination of hydrogen types in solid catalysts and supports.

    Science.gov (United States)

    Kennedy, Gordon J; Afeworki, Mobae; Calabro, David C; Chase, Clarence E; Smiley, Randolph J

    2004-06-01

    Distinct hydrogen species are present in important inorganic solids such as zeolites, silicoaluminophosphates (SAPOs), mesoporous materials, amorphous silicas, and aluminas. These H species include hydrogens associated with acidic sites such as Al(OH)Si, non-framework aluminum sites, silanols, and surface functionalities. Direct and quantitative methodology to identify, measure, and monitor these hydrogen species are key to monitoring catalyst activity, optimizing synthesis conditions, tracking post-synthesis structural modifications, and in the preparation of novel catalytic materials. Many workers have developed several techniques to address these issues, including 1H MAS NMR (magic-angle spinning nuclear magnetic resonance). 1H MAS NMR offers many potential advantages over other techniques, but care is needed in recognizing experimental limitations and developing sample handling and NMR methodology to obtain quantitatively reliable data. A simplified approach is described that permits vacuum dehydration of multiple samples simultaneously and directly in the MAS rotor without the need for epoxy, flame sealing, or extensive glovebox use. We have found that careful optimization of important NMR conditions, such as magnetic field homogeneity and magic angle setting are necessary to acquire quantitative, high-resolution spectra that accurately measure the concentrations of the different hydrogen species present. Details of this 1H MAS NMR methodology with representative applications to zeolites, SAPOs, M41S, and silicas as a function of synthesis conditions and post-synthesis treatments (i.e., steaming, thermal dehydroxylation, and functionalization) are presented.

  17. Development of methodologies used in the areas of safeguards and nuclear forensics based on LA-HR-ICP-MS technique

    International Nuclear Information System (INIS)

    Marin, Rafael Coelho

    2013-01-01

    Environmental sampling performed by means of swipe samples is a methodology frequently employed by International Atomic Energy Agency (IAEA) to verify if the signatory States of the Safeguards Agreements are conducing unauthorized activities. Swipe samples analysis is complementary to the Safeguards ordinary procedures used to verify the information given by the States. In this work it was described a methodology intending to strengthen the nuclear safeguards and nuclear forensics procedures. The proposal is to study and evaluate the laser ablation high resolution inductively coupled plasma mass spectrometry (LA-HR-ICP-MS) technique as an alternative to analyze the real-life swipe samples. The precision achieved through the standard (CRM - 125A) measurements, represented by the relative standard deviation (RSD), was respectively 1.3 %, 0.2 % e 7.6 % for the 234 U/ 238 U, 235 U/ 238 U e 236 U/ 238 U isotopes ratios. The percent uncertainties (u %), which covers the RSD, ranged from 3.5 % to 29.8 % to the 235 U/ 238 U measurements and from 16.6 % to 42.9 % to the 234 U/ 238 U isotope ratio. These results were compatible with former studies performed by the LA-HR-ICP-MS that analyzed real-life swipe samples collected at a nuclear facility. Swipe samples collected from several points of the nuclear facility presented enrichment level ranging from (2.3 ± 0.7) % (sample 3) to (17.3 ± 2.8) % (sample 18). They also allowed detecting different enrichment levels within the facility. (author)

  18. HR Explorer

    CERN Document Server

    Möller, M

    1997-01-01

    At the European Laboratory for Particle Physics Research (CERN), Geneva Switzerland we are using OracleHR for managing our human resources since 1995. After the first year of production it became clear that there was a strong need for an easy-to-use Decision Support Tool exploring the data in OracleHR. This paper illustrates an approach which we have adopted to provide on-line management reporting, multi-dimensional analysis, drill-down and slicing & dicing of data, warehoused from OracleHR. The tool offers strong resource management and planning capabilities including career follow-up. The user management and security monitoring are implemented using the Oracle WebServer.

  19. HR boiler

    Energy Technology Data Exchange (ETDEWEB)

    1982-08-01

    A number of manufacturers of central heating boilers in the Netherlands have produced high-efficiency boilers, all carrying the GIVEG-HR seal of approval (GIVEG is the manufacturers' association in the Netherlands, and HR stands for 'hoog rendement': high efficiency). Efficiences were considerably improved by reducing flue, idling and radiation losses. Control and safety, discharges of flue gases and condensate need special attention. Whether installation of a GIVEG-HR boiler is profitable in view of the cost/profit ratio, will have to be determined from case to case. N.V. Nederlandse Gasunie felt it was time to present the facts so far in a way specially aimed at the construction industry. This special edition of 'Gas and Architecture' answers a number of questions which the architect or consultant engineer might have in particular before advising on the installation of the new boiler in houses and other buildings in the interests of energy saving. A technical description of the HR boiler covers the backgrounds of its development and considers the role of the Netherlands government as regards to the introduction of the boiler.

  20. M-BAND IMAGING OF THE HR 8799 PLANETARY SYSTEM USING AN INNOVATIVE LOCI-BASED BACKGROUND SUBTRACTION TECHNIQUE

    International Nuclear Information System (INIS)

    Galicher, Raphael; Marois, Christian; Macintosh, Bruce; Konopacky, Quinn; Barman, Travis

    2011-01-01

    Multi-wavelength observations/spectroscopy of exoplanetary atmospheres are the basis of the emerging exciting field of comparative exoplanetology. The HR 8799 planetary system is an ideal laboratory to study our current knowledge gap between massive field brown dwarfs and the cold 5 Gyr old solar system planets. The HR 8799 planets have so far been imaged at J- to L-band, with only upper limits available at M-band. We present here deep high-contrast Keck II adaptive optics M-band observations that show the imaging detection of three of the four currently known HR 8799 planets. Such detections were made possible due to the development of an innovative LOCI-based background subtraction scheme that is three times more efficient than a classical median background subtraction for Keck II AO data, representing a gain in telescope time of up to a factor of nine. These M-band detections extend the broadband photometric coverage out to ∼5 μm and provide access to the strong CO fundamental absorption band at 4.5 μm. The new M-band photometry shows that the HR 8799 planets are located near the L/T-type dwarf transition, similar to what was found by other studies. We also confirm that the best atmospheric fits are consistent with low surface gravity, dusty, and non-equilibrium CO/CH 4 chemistry models.

  1. Development of methodologies used in the areas of safeguards and nuclear forensics based on LA-HR-ICP-MS technique; Desenvolvimento de metodologias utilizadas nas areas de salvaguardas e forense nuclear baseadas na tecnica LA-HR-ICP-MS

    Energy Technology Data Exchange (ETDEWEB)

    Marin, Rafael Coelho

    2013-07-01

    Environmental sampling performed by means of swipe samples is a methodology frequently employed by International Atomic Energy Agency (IAEA) to verify if the signatory States of the Safeguards Agreements are conducing unauthorized activities. Swipe samples analysis is complementary to the Safeguards ordinary procedures used to verify the information given by the States. In this work it was described a methodology intending to strengthen the nuclear safeguards and nuclear forensics procedures. The proposal is to study and evaluate the laser ablation high resolution inductively coupled plasma mass spectrometry (LA-HR-ICP-MS) technique as an alternative to analyze the real-life swipe samples. The precision achieved through the standard (CRM - 125A) measurements, represented by the relative standard deviation (RSD), was respectively 1.3 %, 0.2 % e 7.6 % for the {sup 234}U/{sup 238}U, {sup 235}U/{sup 238}U e {sup 236}U/{sup 238}U isotopes ratios. The percent uncertainties (u %), which covers the RSD, ranged from 3.5 % to 29.8 % to the {sup 235}U/{sup 238}U measurements and from 16.6 % to 42.9 % to the {sup 234}U/{sup 238}U isotope ratio. These results were compatible with former studies performed by the LA-HR-ICP-MS that analyzed real-life swipe samples collected at a nuclear facility. Swipe samples collected from several points of the nuclear facility presented enrichment level ranging from (2.3 ± 0.7) % (sample 3) to (17.3 ± 2.8) % (sample 18). They also allowed detecting different enrichment levels within the facility. (author)

  2. Les schémas de sélection ovins laitiers en France : utilisation et importance des techniques modernes de reproduction

    OpenAIRE

    Astruc, J.M.; Lagriffoul, G.; Belloc, J.P.; Briois, M.; Cachenaut, J.B.; Horent, M.H.; Teinturier, M.H.

    1995-01-01

    La mise en oeuvre de programmes de sélection laitière, à l’échelle de toute une population ovine, suppose de développer un travail de sélection entre éleveurs, fondé sur l’organisation et la valorisation de liens génétiques entre troupeaux, essentiellement grâce à l’utilisation de l’IA. La situation en France est à cet égard révélatrice des différents niveaux d’organisation des schémas de sélection.

  3. Increased vascular sympathetic modulation in mice with Mas receptor deficiency

    Science.gov (United States)

    Rabello Casali, Karina; Ravizzoni Dartora, Daniela; Moura, Marina; Bertagnolli, Mariane; Bader, Michael; Haibara, Andrea; Alenina, Natalia; Irigoyen, Maria Claudia; Santos, Robson A

    2016-01-01

    Introduction: The angiotensin-converting enzyme 2 (ACE2)/angiotensin (Ang)-(1–7)/Mas axis could modulate the heart rate (HR) and blood pressure variabilities (BPV) which are important predictors of cardiovascular risk and provide information about the autonomic modulation of the cardiovascular system. Therefore we investigated the effect of Mas deficiency on autonomic modulation in wild type and Mas-knockout (KO) mice. Methods: Blood pressure was recorded at high sample rate (4000 Hz). Stationary sequences of 200–250 beats were randomly chosen. Frequency domain analysis of HR and BPV was performed with an autoregressive algorithm on the pulse interval sequences and on respective systolic sequences. Results: The KO group presented an increase of systolic arterial pressure (SAP; 127.26±11.20 vs 135.07±6.98 mmHg), BPV (3.54±1.54 vs 5.87±2.12 mmHg2), and low-frequency component of systolic BPV (0.12±0.11 vs 0.47±0.34 mmHg2). Conclusions: The deletion of Mas receptor is associated with an increase of SAP and with an increased BPV, indicating alterations in autonomic control. Increase of sympathetic vascular modulation in absence of Mas evidences the important role of Ang-(1–7)/Mas on cardiovascular regulation. Moreover, the absence of significant changes in HR and HRV can indicate an adaptation of autonomic cardiac balance. Our results suggest that the Ang-(1–7)/Mas axis seems more important in autonomic modulation of arterial pressure than HR. PMID:27080540

  4. Digitalisering og HR

    DEFF Research Database (Denmark)

    Kühn Pedersen, Mogens

    2017-01-01

    Digitalisering står ligesom HR for et omfattende fag- og praksisfelt. Såvel praksis som teknologiudvikling styrer feltets stadige forandringer.......Digitalisering står ligesom HR for et omfattende fag- og praksisfelt. Såvel praksis som teknologiudvikling styrer feltets stadige forandringer....

  5. E/Z MAS demonstration

    International Nuclear Information System (INIS)

    Boor, M.G.; Hurford, J.M.; Landry, R.P.; Martinez, B.J.; Solem, A.M.; Whiteson, R.; Zardecki, A.

    1998-01-01

    Los Alamos National Laboratory has developed E/Z MAS, a new generation nuclear material accountability application based on the latest technology and designed for facilities required to track nuclear materials with a simple-to-use interface. E/Z MAS is based on years of experience spent developing nuclear material accounting systems. E/Z MAS uses a modern relational database with a web server and enables users on a classified local area network to interact with the database with web browsers. The E/Z MAS Demonstration poster session demonstrates the E/Z MAS functions required by an operational nuclear facility to track material as it enters and leaves a facility and to account for the material as it moves through a process. The generation of internal facility reports and external reports for the Russian Federal system will be demonstrated. Bar-code readers will be used to demonstrate the ability of EZ MAS to automate certain functions, such as physical inventories at facilities

  6. Quartz Crystal Temperature Sensor for MAS NMR

    Science.gov (United States)

    Simon, Gerald

    1997-10-01

    Quartz crystal temperature sensors (QCTS) were tested for the first time as wireless thermometers in NMR MAS rotors utilizing the NMR RF technique itself for exiting and receiving electro-mechanical quartz resonances. This new tool in MAS NMR has a high sensitivity, linearity, and precision. When compared to the frequently used calibration of the variable temperature in the NMR system by a solid state NMR chemical shift thermometer (CST), such as lead nitrate, QCTS shows a number of advantages. It is an inert thermometer in close contact with solid samples operating parallel to the NMR experiment. QCTS can be manufactured for any frequency to be near a NMR frequency of interest (typically 1 to 2 MHz below or above). Due to the strong response of the crystal, signal detection is possible without changing the tuning of the MAS probe. The NMR signal is not influenced due to the relative sharp crystal resonance, restricted excitation by finite pulses, high probeQvalues, and commonly used audio filters. The quadratic dependence of the temperature increase on spinning speed is the same for the QCTS and for the CST lead nitrate and is discussed in terms of frictional heat in accordance with the literature about lead nitrate and with the results of a simple rotor speed jump experiment with differently radial located lead nitrate in the rotor.

  7. Er HR ude i tovene?

    DEFF Research Database (Denmark)

    Poulfelt, Flemming

    2015-01-01

    HR: Er der behov for nytænkning i HR-land? Artikler i Harvard Business Review - bakket op af en dansk undersøgelse - konkluderer, at HR stadig mangler gennemslagskraft i virksomhederne. Er HR ude i tovene? ... For i undersøgelsen "Ny Dansk Ledelse" (maj 2015), som er baseret på danske lederes...

  8. Occasioning change through HR sourcing

    NARCIS (Netherlands)

    van Balen, Mitchell; Bondarouk, Tatiana; Strohmeier, Stefan; Diederichsen, Anke

    2010-01-01

    This article describes how structuration theory can be used to analyze changes as invoked by two HR Sourcing arrangements: HR Shared Service Centers and HR Outsourcing. This approach allows us to under-stand changing responsibilities, altered HR processes, and the adaptation of web-based tools for

  9. Study on in vivo examination of tumors of epithelial origin for the monoclonales antibodies ior c5, ior egf/r3 and humanized hr3, by using inmunogammagraphy technique

    International Nuclear Information System (INIS)

    Ramos Suzarte, Mayra; Iznaga Escobar, Normando; Torres Gemil, Olga; Rodriguez Obaya, Teresita; Perez Rodriguez, Rolando; Rodriguez Mesa, Nelson; Oliva Gonzalez, Juan P.; Perera Pintado, Alejandro; Torres Aroche, Leonel; Batista Cuellar, Juan; Gonzalez Lazo, Nery; Cruz, Teresa; Leonard, Ibrahim; Neninger, Elia

    2003-01-01

    The present work is aimed at demonstrating that humanized hR3 and ior egf/r3, ior c5, ior cea-1 murine monoclonal antibodies (mAbs) can identify primary neoplasia lesions, Their post-surgical received and metastasis by using immunography, Results showed that above mentioned mAbs are useful for the diagnosis of epithelial tumors, their metastasis and post-surgical received. this technique becomes a concept prove for further use of mAbs in cancer therapy

  10. High Tech M&As

    DEFF Research Database (Denmark)

    Toppenberg, Gustav

    2013-01-01

    Technology driven industries have seen fast moving technology changes, higher complexity and reduced product life cycles. These emerging trends present challenges for companies in industries where technology is at the forefront. The extant research deals with ‘low-tech’ industries and majority...... of findings are not applicable to the high-tech industry; in fact this industry has many additional challenges. In this study, we aim to explore the process of M&A in the high-tech industry by drawing on extant literature and empirical field work. The paper outlines a research project in progress which...... intends to provide theoretical, empirical and practical contributions in answering the research question: what role does Operations and IT play in creating value in high-tech M&As? The research adds a needed perspective on M&A literature by unveiling unique challenges and opportunities faced by the M...

  11. HR-MAS NMR metabolomics of 'Swingle' citrumelo rootstock genetically modified to overproduce proline.

    Science.gov (United States)

    de Oliveira, Caroline S; Carlos, Eduardo F; Vieira, Luiz G E; Lião, Luciano M; Alcantara, Glaucia B

    2014-08-01

    The accumulation of proline is a typical physiological response to abiotic stresses in higher plants. 'Swingle' citrumelo, an important rootstock for citrus production, has been modified with a mutated Δ(1)-pyrroline-5-carboxylate synthetase gene (VaP5CSF129A) linked to the cauliflower mosaic virus 35S promoter to induce the overproduction of free proline. This paper presents a comparative metabolomic study of nontransgenic versus transgenic 'Swingle' citrumelo plants with high endogenous proline. (1)H high-resolution magic angle spinning nuclear magnetic resonance spectroscopy and multivariate analysis showed significant differences in some metabolites between the nontransgenic and transgenic leaves and roots. The overproduction of proline has reduced the sucrose content in transgenic leaves, revealing a metabolic cost for these plants. In roots, the high level of free proline acts for the adjustment of cation-anion balance, causing the reduction of acetic acid content. The same sucrose level in roots indicates that they can be considered as sucrose sink. Similar behavior may be waited for fruits produced on transgenic rootstock. Copyright © 2014 John Wiley & Sons, Ltd.

  12. Fluid flow dynamics in MAS systems

    Science.gov (United States)

    Wilhelm, Dirk; Purea, Armin; Engelke, Frank

    2015-08-01

    The turbine system and the radial bearing of a high performance magic angle spinning (MAS) probe with 1.3 mm-rotor diameter has been analyzed for spinning rates up to 67 kHz. We focused mainly on the fluid flow properties of the MAS system. Therefore, computational fluid dynamics (CFD) simulations and fluid measurements of the turbine and the radial bearings have been performed. CFD simulation and measurement results of the 1.3 mm-MAS rotor system show relatively low efficiency (about 25%) compared to standard turbo machines outside the realm of MAS. However, in particular, MAS turbines are mainly optimized for speed and stability instead of efficiency. We have compared MAS systems for rotor diameter of 1.3-7 mm converted to dimensionless values with classical turbomachinery systems showing that the operation parameters (rotor diameter, inlet mass flow, spinning rate) are in the favorable range. This dimensionless analysis also supports radial turbines for low speed MAS probes and diagonal turbines for high speed MAS probes. Consequently, a change from Pelton type MAS turbines to diagonal turbines might be worth considering for high speed applications. CFD simulations of the radial bearings have been compared with basic theoretical values proposing considerably smaller frictional loss values. The discrepancies might be due to the simple linear flow profile employed for the theoretical model. Frictional losses generated inside the radial bearings result in undesired heat-up of the rotor. The rotor surface temperature distribution computed by CFD simulations show a large temperature gradient over the rotor.

  13. Hierarchical MAS based control strategy for microgrid

    Energy Technology Data Exchange (ETDEWEB)

    Xiao, Z.; Li, T.; Huang, M.; Shi, J.; Yang, J.; Yu, J. [School of Information Science and Engineering, Yunnan University, Kunming 650091 (China); Xiao, Z. [School of Electrical and Electronic Engineering, Nanyang Technological University, Western Catchment Area, 639798 (Singapore); Wu, W. [Communication Branch of Yunnan Power Grid Corporation, Kunming, Yunnan 650217 (China)

    2010-09-15

    Microgrids have become a hot topic driven by the dual pressures of environmental protection concerns and the energy crisis. In this paper, a challenge for the distributed control of a modern electric grid incorporating clusters of residential microgrids is elaborated and a hierarchical multi-agent system (MAS) is proposed as a solution. The issues of how to realize the hierarchical MAS and how to improve coordination and control strategies are discussed. Based on MATLAB and ZEUS platforms, bilateral switching between grid-connected mode and island mode is performed under control of the proposed MAS to enhance and support its effectiveness. (authors)

  14. MAS NMR of HIV-1 protein assemblies

    Science.gov (United States)

    Suiter, Christopher L.; Quinn, Caitlin M.; Lu, Manman; Hou, Guangjin; Zhang, Huilan; Polenova, Tatyana

    2015-04-01

    The negative global impact of the AIDS pandemic is well known. In this perspective article, the utility of magic angle spinning (MAS) NMR spectroscopy to answer pressing questions related to the structure and dynamics of HIV-1 protein assemblies is examined. In recent years, MAS NMR has undergone major technological developments enabling studies of large viral assemblies. We discuss some of these evolving methods and technologies and provide a perspective on the current state of MAS NMR as applied to the investigations into structure and dynamics of HIV-1 assemblies of CA capsid protein and of Gag maturation intermediates.

  15. PROPAGANDA POLITIK PARTAI GERINDRA DALAM GAME MAS GARUDA PADA PEMILU 2014 (Analisis Deskriptif Game Online Mas Garuda

    Directory of Open Access Journals (Sweden)

    Angga Satrya Putra

    2016-03-01

    Full Text Available The purpose of this study was to determine how the meaning of the look and content of the online game “Garuda Mas”. This game contains aspects of politically charged designations so that it can become a propaganda technique. The subject of this study is the game “Garuda Mas” which has been input on social media Facebook.Methods of data collection using documentary and literature. Data analysis using descriptive techniques. Data validity checking techniques using triangulation source.The results showed that the game “MAS GARUDA” can form the perspective of the players against Mas Garuda as a superhero figure hopes the Indonesian people who are able to overcome all the problems that exist in Indonesia. This game is a form of creative campaigns using propaganda techniques inserted in the game that has the power to change the mindset of every player. Change of mindset occurs because the player did not have an opportunity to think critically on aspects marking contained in the game. By indirectly the players will feel the emotional of this game and assume characterizations “Garuda Mas” in this game is a truth that can be believed.Keywords: Descriptive, Online Games, Mas Garuda, Partai Gerindra

  16. Determination of trace elements in high pure rare earth oxide by double focusing inductively coupled plasma mass spectrometry (HR ICP-MS) and high performance liquid chromatography (HPLC) techniques

    International Nuclear Information System (INIS)

    Pedreira Filho, Walter dos Reis

    2000-01-01

    Rare earth oxides are used in several technological fields whose applications can be observed in several areas of modern technology, among which are included: lasers, semiconductors semi, high purity materials and metallic alloys. The field of applications of the rare earth elements is quite wide. Several important industrial applications are ceramics, catalysts and metallurgical as well as research areas and high technology sectors. Such applications have been presenting an accentuated growth in the last years. Chemical characterization of rare earth oxides of high purity has been constituting one of the major challenges of analytical chemistry. Several analytical techniques were used for chemical characterization of high purity rare earth the oxides. Even so, those techniques present limitations when one needs to characterize materials of a high level of purity, as in the case of rare earth oxides. Some of those limitations are associated, for example, to spectral interference. Inductively Coupled Plasma Mass Spectrometry (ICP-MS) is a powerful analytical tool for quantitative analysis of metal impurities in high purity materials. The Instituto de Pesquisas Energeticas e Nucleares (IPEN) has an unit of production and purification of rare earth oxides, with above 99,9% level of purity. In this work, the rare earth impurities were characterized in samples (La 2 O 3 ; CeO 2 ; Pr 6 O 11 ; Nd 2 O 3 ; Sm 2 O 3 ; Gd 2 O 3 ; Y 2 O 3 ) produced at the IPEN and certified standard materials produced by Johnson Matthey Chemical (JMC). The technique of high performance liquid chromatography (HPLC) was used in the separation of the impurities. Quantification of metallic impurities was carried out as inductively coupled plasma mass spectrometer (HR-ICP MS). In this work it is presented a new analytical methodology in the chemical characterization of metallic impurities in rare earth oxides of high purity (> 99,9%) with and without separation of the matrix. Analyses of standard

  17. Hr Pitt mängib hr Smithi / Timo Diener

    Index Scriptorium Estoniae

    Diener, Timo

    2005-01-01

    Brad Pitt actionkomöödias "Hr ja pr Smith" ("Mr and Mrs Smith") : režissöör Doug Liman : Ameerika Ühendriigid 2005. Filmi ümber puhkenud skandaalist ning näitleja plaanitavatest filmirollidest aastal 2006

  18. UAV Robust Strategy Control Based on MAS

    Directory of Open Access Journals (Sweden)

    Jian Han

    2014-01-01

    Full Text Available A novel multiagent system (MAS has been proposed to integrate individual UAV (unmanned aerial vehicle to form a UAV team which can accomplish complex missions with better efficiency and effect. The MAS based UAV team control is more able to conquer dynamic situations and enhance the performance of any single UAV. In this paper, the MAS proposed and established combines the reacting and thinking abilities to be an initiative and autonomous hybrid system which can solve missions involving coordinated flight and cooperative operation. The MAS uses BDI model to support its logical perception and to classify the different missions; then the missions will be allocated by utilizing auction mechanism after analyzing dynamic parameters. Prim potential algorithm, particle swarm algorithm, and reallocation mechanism are proposed to realize the rational decomposing and optimal allocation in order to reach the maximum profit. After simulation, the MAS has been proved to be able to promote the success ratio and raise the robustness, while realizing feasibility of coordinated flight and optimality of cooperative mission.

  19. Putting HR outsourcing into practice.

    Science.gov (United States)

    Berger, Michael

    2007-01-01

    Faced with the time-consuming responsibility of human resources (HR) management, a growing number of medical practices are outsourcing their HR to professional employer organizations (PEOs) so they can concentrate on their core business. A PEO functions as an HR department-minus the high overhead-managing daily administrative tasks such as payroll processing and related tax filings, employee benefits, and workers' compensation coverage and claims resolution. PEOs help physicians' offices keep up with the piles of paperwork that never seem to shrink, freeing doctors to focus on patient care and building their practice. Because of their volume buying power, PEOs are able to offer employees of small medical practices big-company benefits-everything from health, dental, and vision coverage to long-term disability insurance and tuition assistance. A fledgling industry only a decade ago, HR outsourcing has morphed into a blossoming industry. Enlisting the services of a PEO is now considered de rigueur in many small business circles.

  20. MIGRATION OF ORACLE HR DATABASE

    CERN Multimedia

    ais.support@cern.ch

    2001-01-01

    Restricted services from 3 to 7 November 2001 Due to the migration of the Oracle HR application to the Web, some services which rely on the application's availability may be disturbed from Friday 2 November at 17:30 until Thursday 8 November at 08:30. Amongst those services: HR Division: records office, recruitment, claims and benefits. FI Division: personnel accounting, advances and claims. ST Division: registration office (access cards). SPL Division: external firm staff records. EP Division: users' office. Experiments' secretariats: PIE, Greybook. Divisional secretariats: externals, internal addresses. All information concerning this migration is available at: http://ais.cern.ch We apologize for any inconvenience and thank you in advance for your understanding.

  1. Perspective of MAS in Power System via a Fuzzy Framework

    Directory of Open Access Journals (Sweden)

    S. Razini

    2017-03-01

    Full Text Available Multi agent systems (MAS are popularly used in practice, however; a few studies have looked at MAS capabilities from the power engineering perspective. This paper presents the results of an investigation concerning the compatibility of MAS capabilities in different power engineering categories. Five MAS capabilities and seven power system categories are established. A framework for applying MAS in power engineering is developed. A fuzzy inference system is adopted to evaluate the paper proposed framework. Two approaches, namely simulation and real, are considered for different power categories. The paper shows that MAS capabilities are generally compatible with both approaches, although compatibility of MAS with real approach is more significant. The paper concludes that in the near future MAS is anticipated to be a key important tool in the development of intelligent systems and smart grids in power system. This paper contributes to thinking on perspective of MAS in power System.

  2. Next HR Department Public meeting

    CERN Multimedia

    2012-01-01

      Dear Colleagues, I am pleased to invite you to the next public meeting organized by HR Department, which will take place on Monday 25 June at 14:30, for the first time in the Globe (in front of the Reception). The agenda will comprise of: ·         the recent staff member survey results ·         the Diversity at CERN ·         the Learning and Development Policy The first topic concerns, more specifically, staff members. All presentations will be made in English, however, we are pleased to inform you that a simultaneous interpretation in French is foreseen. Should you not be able to attend the meeting, it can also be followed via Webcast and the recording will be made available on Indico. Finally, subject to a favourable weather, refreshments...

  3. Next HR Department public meeting

    CERN Multimedia

    2016-01-01

    Dear Colleagues, I am pleased to invite you to the next public meeting organized by the HR Department, which will take place on Tuesday 28 June at 3 p.m. in the Council Chamber. A drink will be served after the meeting as of 16:30 This meeting will be the opportunity to revisit the specificities of the Career Structure measures and Benchmark Jobs, what they entail and how they will be implemented, and to answer your questions. This meeting is also important for me on a personal note, as I will bid you farewell, at least for a few years, taking special leave as of 1 August 2016 to take up the position of Director-General for Human Resources at the European Central Bank in Frankfurt.  Should you not be able to attend the meeting, it can also be followed via Webcast and the recording will be made available on Indico. I look forward to meeting you. Best regards, Anne-Sylvie Catherin Head of the Human Resources Department

  4. Réunion publique HR

    CERN Multimedia

    CERN. Geneva

    2010-01-01

    Chers Collègues,Je me permets de vous rappeler qu'une réunion publique organisée par le Département HR se tiendra aujourd'hui:Vendredi 30 avril 2010 à 9h30 dans l'Amphithéâtre principal (café offert dès 9h00).Durant cette réunion, des informations générales seront données sur:le CERN Admin e-guide, qui est un nouveau guide des procédures administratives du CERN ayant pour but de faciliter la recherche d'informations pratiques et d'offrir un format de lecture convivial;le régime d'Assurance Maladie de l'Organisation (présentation effectuée par Philippe Charpentier, Président du CHIS Board) et;la Caisse de Pensions (présentation effectuée par Théodore Economou, Administrateur de la Caisse de Pensions du CERN).Une transmission simultanée de cette réunion sera assur...

  5. Esprit HR mattress cover in pressure ulcer prevention.

    Science.gov (United States)

    Khoulowa, J

    Modern mattresses provide soft dense foam, which permits the redistribution of pressure on the patient over a wider area - away from bony prominences where pressure ulcers usually occur. The material used in producing multistretch covers for the new mattresses had a tendency to delaminate as a result of a combination of heat, moisture and inappropriate cleansing techniques causing the water barriers to fall. In partnership with York Health NHS Trust and the material manufacturer, STM Healthcare produced a mattress cover (Esprit HR) which was able to withstand higher pressure from heat and moisture and greatly extended the life expectancy of the Esprit HR mattress.

  6. The perspective of Malaysian Manufacturing Organizations on Strategy, HR Outsourcing and HR Costs

    Directory of Open Access Journals (Sweden)

    Hasliza Abdul HALIM

    2011-06-01

    Full Text Available The paper discusses the relationship between different types of human resource management (HRM strategy and the human resource outsourcing, and impact on the size of human resource (HR department. Three HRM strategies are considered: Facilitation, accumulation and utilization. The data for the study were obtained from survey responses from 232 organizations, of which 113 were engaged in HR outsourcing. The findings suggest that organizations tend to rely on outsourcing of HR functions when they espouse facilitation and utilization HRM strategy. Concurrently, by relying on HR outsourcing, the organizations manage to experience a reduction in the size of HR department. The results show that it is important for the organizations to better understand the implications of an increased reliance on outsourcing within HR. This allows them to focus on how HR functions are delivered within organizations with the interaction of HRM strategy and the size of HR department will tend to be smaller resulting from outsourcing activities.

  7. Adding intrapreneurial role in HR business partner model: (an extension in the HR business partner model)

    OpenAIRE

    Bashir, Jibran; Afzal, Sara

    2009-01-01

    Purpose: The Purpose of this paper is to introduce a concept, whereby extending the Dave Ulrich’s HR business partner model by adding fifth Role – The HR Intrapreneur Role – in the existing model. This will be done by combining two separate concepts “Four Roles HR Business Partner Model” and “Intrapreneurial HR”, resulting in a five roles HR Business Partner Model. Design/methodology/approach: This paper is introducing a new concept through theoretical research. Findings: H...

  8. Authenticity study of Phyllanthus species by NMR and FT-IR techniques coupled with chemometric methods

    International Nuclear Information System (INIS)

    Santos, Maiara S.; Pereira-Filho, Edenir R.; Ferreira, Antonio G.; Boffo, Elisangela F.; Figueira, Glyn M.

    2012-01-01

    The importance of medicinal plants and their use in industrial applications is increasing worldwide, especially in Brazil. Phyllanthus species, popularly known as 'quebra-pedras' in Brazil, are used in folk medicine for treating urinary infections and renal calculus. This paper reports an authenticity study, based on herbal drugs from Phyllanthus species, involving commercial and authentic samples using spectroscopic techniques: FT-IR, 1 H HR-MAS NMR and 1 H NMR in solution, combined with chemometric analysis. The spectroscopic techniques evaluated, coupled with chemometric methods, have great potential in the investigation of complex matrices. Furthermore, several metabolites were identified by the NMR techniques. (author)

  9. Authenticity study of Phyllanthus species by NMR and FT-IR Techniques coupled with chemometric methods

    Directory of Open Access Journals (Sweden)

    Maiara S. Santos

    2012-01-01

    Full Text Available The importance of medicinal plants and their use in industrial applications is increasing worldwide, especially in Brazil. Phyllanthus species, popularly known as "quebra-pedras" in Brazil, are used in folk medicine for treating urinary infections and renal calculus. This paper reports an authenticity study, based on herbal drugs from Phyllanthus species, involving commercial and authentic samples using spectroscopic techniques: FT-IR, ¹H HR-MAS NMR and ¹H NMR in solution, combined with chemometric analysis. The spectroscopic techniques evaluated, coupled with chemometric methods, have great potential in the investigation of complex matrices. Furthermore, several metabolites were identified by the NMR techniques.

  10. Authenticity study of Phyllanthus species by NMR and FT-IR techniques coupled with chemometric methods

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Maiara S.; Pereira-Filho, Edenir R.; Ferreira, Antonio G. [Universidade Federal de Sao Carlos (UFSCAR), SP (Brazil). Dept. de Quimica; Boffo, Elisangela F. [Universidade Federal da Bahia (UFBA), Salvador, BA (Brazil). Inst. de Quimica; Figueira, Glyn M., E-mail: maiarassantos@yahoo.com.br [Universidade Estadual de Campinas (UNICAMP), Campinas, SP (Brazil). Centro Pluridisciplinar de Pesquisas Quimicas, Biologicas e Agricolas

    2012-07-01

    The importance of medicinal plants and their use in industrial applications is increasing worldwide, especially in Brazil. Phyllanthus species, popularly known as 'quebra-pedras' in Brazil, are used in folk medicine for treating urinary infections and renal calculus. This paper reports an authenticity study, based on herbal drugs from Phyllanthus species, involving commercial and authentic samples using spectroscopic techniques: FT-IR, {sup 1}H HR-MAS NMR and {sup 1}H NMR in solution, combined with chemometric analysis. The spectroscopic techniques evaluated, coupled with chemometric methods, have great potential in the investigation of complex matrices. Furthermore, several metabolites were identified by the NMR techniques. (author)

  11. Authenticity study of Phyllanthus species by NMR and FT-IR techniques coupled with chemometric methods

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Maiara S.; Pereira-Filho, Edenir R.; Ferreira, Antonio G. [Universidade Federal de Sao Carlos (UFSCAR), SP (Brazil). Dept. de Quimica; Boffo, Elisangela F. [Universidade Federal da Bahia (UFBA), Salvador, BA (Brazil). Inst. de Quimica; Figueira, Glyn M., E-mail: maiarassantos@yahoo.com.br [Universidade Estadual de Campinas (UNICAMP), Campinas, SP (Brazil). Centro Pluridisciplinar de Pesquisas Quimicas, Biologicas e Agricolas

    2012-07-01

    The importance of medicinal plants and their use in industrial applications is increasing worldwide, especially in Brazil. Phyllanthus species, popularly known as 'quebra-pedras' in Brazil, are used in folk medicine for treating urinary infections and renal calculus. This paper reports an authenticity study, based on herbal drugs from Phyllanthus species, involving commercial and authentic samples using spectroscopic techniques: FT-IR, {sup 1}H HR-MAS NMR and {sup 1}H NMR in solution, combined with chemometric analysis. The spectroscopic techniques evaluated, coupled with chemometric methods, have great potential in the investigation of complex matrices. Furthermore, several metabolites were identified by the NMR techniques. (author)

  12. Welding Metallurgy of Alloy HR-160

    International Nuclear Information System (INIS)

    DuPont, J.N.; Michael, J.R.; Newbury, B.D.

    1999-01-01

    The solidification behavior and resultant solidification cracking susceptibility of autogenous gas tungsten arc fusion welds in alloy HR-160 was investigated by Varestraint testing, differential thermal analysis, and various microstructural characterization techniques. The alloy exhibited a liquidus temperature of 1387 degC and initiated solidification by a primary L - γ reaction in which Ni, Si, and Ti segregated to the interdendritic liquid and Co segregated to the γ dendrite cores. Chromium exhibited no preference for segregation to the solid or liquid phase during solidification. Solidification terminated at ∼ 1162 degC by a eutectic-type L - [γ+ (Ni,Co) 16 (Ti,Cr) 6 Si 7 ] reaction. The (Ni,Co) 16 (Ti,Cr) 6 Si 7 phase is found to be analogous to the G phase which forms in the Ni-Ti-Si and Co-Ti-Si ternary systems, and similarities are found to exist between the solidification behavior of this commercial multicomponent alloy and the simple Ni-Si and Ni-Ti binary systems. Reasonable agreement is obtained between the calculated and measured volume percent of the [γ +(Ni,Co) l6 (Ti,Cr) 6 Si 7 ] eutectic-typr constituent with the Scheil equation using experimentally determined k values for Si and Ti from electron microprobe data. The alloy exhibited a very high susceptibility to solidification cracking in the Varestraint test. This is attributed to a large solidification temperature range of 225 degC and the presence of 2 to 5 vol% solute rich interdendritic liquid which preferentially wets the grain boundaries and interdendritic regions

  13. DAMPAK KEBIJAKAN PEMERINTAH TERHADAP KOMODITAS PISANG MAS KIRANA

    Directory of Open Access Journals (Sweden)

    Ariq Dewi Maharani

    2016-10-01

    Full Text Available ABSTRAKPenelitian ini bertujuan untuk menganalisis aspek profitabilitas pisang mas Kirana di Kabupaten Lumajang, dan menganalisis dampak kebijakan pemerintah terhadap pisang mas Kirana di Kabupaten Lumajang. Penentuan lokasi dilakukan secara sengaja (purposive method di Kabupaten Lumajang. Data yang digunakan meliputi data primer dan data sekunder. Analisa data menggunakan Policy Analysis Matrix (PAM untuk menganalisis aspek profitabilitas dan dampak kebijakan pemerintah terhadap pisang mas Kirana. Hasil penelitian menunjukkan bahwa Komoditas pisang mas Kirana menguntungkan secara finansial dan ekonomi yang ditunjukkan dengan keuntungan privat (PP Rp 10.444.911,8 per hektar dan keuntungan sosial (SP sebesar Rp 23.108.983,7 per hektar. Keuntungan privat pisang mas Kirana lebih kecil daripada keuntungan sosialnya (PPmas Kirana, terdapat dampak kebijakan subsidi terhadap harga-harga input pada usahatani pisang mas Kirana; masih belum ada lembaga yang dapat memberikan pelayanan yang kompetitif serta informasi yang lengkap dan rendahnya harga beli pisang mas Kirana di dalam negeri. ABSTRACTThe purpose of this research for: to analyse the aspect of profitability Kirana Mas banana and to analyse impact of government policy on Kirana Mas banana in Lumajang District. Determination of location was done intentionally or purposive method in Lumajang regency. The data that was used covering primary data and secondary data. Data analysis used Policy Analysis Matrix (PAM for knowing of profitability aspect and impact of government policy on Kirana Mas banana. The results showed that Commodity of Kirana Mas banana has financially and economically beneficial, shown by private profit (PP Rp 10,444,911.8 per hectare and social benefits (SP Rp 23,108,983.7 per hectare. Private profits of “Kirana mas” banana are smaller than social benefit (PP

  14. CAMEX-4 ER-2 MODIS AIRBORNE SIMULATOR (MAS) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The MODIS Airborne Simulator (MAS) is an airborne scanning spectrometer that acquires high spatial resolution imagery of cloud and surface features from its vantage...

  15. The perspective of Malaysian Manufacturing Organizations on Strategy, HR Outsourcing and HR Costs

    OpenAIRE

    Hasliza Abdul HALIM; Norbani CHE-HA

    2011-01-01

    The paper discusses the relationship between different types of human resource management (HRM) strategy and the human resource outsourcing, and impact on the size of human resource (HR) department. Three HRM strategies are considered: Facilitation, accumulation and utilization. The data for the study were obtained from survey responses from 232 organizations, of which 113 were engaged in HR outsourcing. The findings suggest that organizations tend to rely on outsourcing of HR functions when ...

  16. Composite Spectra Paper 1: HR 6902

    Indian Academy of Sciences (India)

    tribpo

    spectra; in many cases we have used the maximum width permitted by the optics of ... 10 mЕ, corresponding to 1 µm the plate, are the norm. ..... an inequality ..... on the spectra of HR 6902, we have thought it appropriate to weight the four ...

  17. Journeys on the H-R diagram

    International Nuclear Information System (INIS)

    Kaler, J.B.

    1988-01-01

    The evolution of various types of stars along the H-R diagram is discussed. Star birth and youth is addressed, and the events that occur due to core contraction, shell burning, and double-shell burning are described. The evolutionary courses of planetary nebulae, white dwarfs, and supernovas are examined

  18. MAS: Malware Analysis System Based on Hardware-Assisted Virtualization Technology

    Science.gov (United States)

    Kim, Taehyoung; Kim, Inhyuk; Min, Changwoo; Eom, Young Ik

    There are many analysis techniques in order to analyze malicious codes. However, recently malicious codes often evade detection using stealthy obfuscation techniques, and attack computing systems. We propose an enhanced dynamic binary instrumentation using hardware-assisted virtualization technology. As a machine-level analyzer, our system can be isolated from almost the whole threats of malware, and provides single step analysis environment. Proposed system also supports rapid system call analysis environment. We implement our malware analysis system (referred as MAS) on the KVM hypervisor with Intel VT-x virtualization support. Our experiments with benchmarks show that the proposed system provides efficient analysis environment with low overhead.

  19. 1H High Resolution Magic-Angle Coil Spinning (HR-MACS µNMR Metabolic Profiling of whole Saccharomyces cervisiae cells: A Demonstrative Study

    Directory of Open Access Journals (Sweden)

    Alan eWong

    2014-06-01

    Full Text Available The low sensitivity of Nuclear Magnetic Resonance (NMR is its prime shortcoming compared to other analytical methods for metabolomic studies. It relies on large sample volume (30–50 µl for HR-MAS for rich metabolic profiling, hindering high-throughput screening especially when the sample requires a labor-intensive preparation or is a sacred specimen. This is indeed the case for some living organisms. This study evaluates a 1H HR-MAS approach for metabolic profiling of small volume (250 nl whole bacterial cells, Saccharomyces cervisiae, using an emerging micro-NMR technology: high-resolution magic-angle coil spinning (HR-MACS. As a demonstrative study for whole cells, we perform two independent metabolomics studies identifying the significant metabolites associated with osmotic stress and aging.

  20. Enabling quaternion derivatives: the generalized HR calculus

    Science.gov (United States)

    Xu, Dongpo; Jahanchahi, Cyrus; Took, Clive C.; Mandic, Danilo P.

    2015-01-01

    Quaternion derivatives exist only for a very restricted class of analytic (regular) functions; however, in many applications, functions of interest are real-valued and hence not analytic, a typical case being the standard real mean square error objective function. The recent HR calculus is a step forward and provides a way to calculate derivatives and gradients of both analytic and non-analytic functions of quaternion variables; however, the HR calculus can become cumbersome in complex optimization problems due to the lack of rigorous product and chain rules, a consequence of the non-commutativity of quaternion algebra. To address this issue, we introduce the generalized HR (GHR) derivatives which employ quaternion rotations in a general orthogonal system and provide the left- and right-hand versions of the quaternion derivative of general functions. The GHR calculus also solves the long-standing problems of product and chain rules, mean-value theorem and Taylor's theorem in the quaternion field. At the core of the proposed GHR calculus is quaternion rotation, which makes it possible to extend the principle to other functional calculi in non-commutative settings. Examples in statistical learning theory and adaptive signal processing support the analysis. PMID:26361555

  1. KINERJA USAHA TANAMAN HIAS POTONG PT PESONA DAUN MAS ASRI

    Directory of Open Access Journals (Sweden)

    Muhamad Arief Bangun Sanjaya

    2017-01-01

    Full Text Available Pesona Daun Mas Asri is a company in cut flowers  and leaves cultivation. The  achievement is shown by the performance of the company. The overall company’s performance contributes in developing the company’s vision. Balanced score card is a management tool used to observe and maintain the stability between financial indicators (financial perspective and non financial indicators (customer, business internal process, growth and learning.  The objective of the journal is to plan the performance of the company using balanced scorecard approach, analyze and calculate the vision, mission and strategy implemented by Pesona Daun Mas in it business activity..  The result for every strategic target shows that the performance of Pesona Daun Mas is excellent with the achieved score of 78,04%.  However the target for the selling growth level and marketing activities are classified as average which means that it still needs to be developed.   Keywords:  balanced scorecard, performance evaluation, KPI performance index, ornamental plants cutAbstrakPesona Daun Mas Asri merupakan perusahaan yang bergerak dalam bidang budi daya bunga potong dan daun potong. Pencapaian dalam menjalankan sebuah perusahaan dapat dilihat dari kinerja perusahaan tersebut.Kinerja perusahaan Pesona Daun Mas Asri secara keseluruhan dapat berkontribusi untuk mengembangkan perusahaan dalam mencapai visi. Balanced scorecard adalah salah satu alat manajemen yang dapat melihat dan menjaga keseimbangan antara indikator keuangan (perspektif keuangan dan indikator non-keuangan (pelanggan, proses bisnisinternal, pertumbuhan dan pembelajaran. Tujuan dari jurnal ini adalah untuk merancang pengukuran kinerja perusahaan dengan pendekatan Balanced scorecard. Penelitian ini juga bertujuan menganalisis dan mengukur pelaksanaan visi, misi dan strategi yang dijalankan oleh Pesona Daun Mas Asri dalam kegiatan bisnisnya. Selain itu, memberikan saran dan rekomendasi, serta merumuskan implikasi

  2. 31P Solid-state MAS NMR spectra

    International Nuclear Information System (INIS)

    Grobet, P.J.; Geerts, H.; Martens, J.A.; Jacobs, P.A.

    1989-01-01

    The structures of the silicoaluminiophosphates MCM-1 and MCM9 were characterized by 27 Al and 31 P MAS NMR. The structural identity of MCM-1 and its silicon-free homologue AlPO 4 -H 3 is demonstrated. The presence of a structural mixture in MCM-9 is confirmed. 31 P MAS NMR spectra of MCM-9 could be interpreted as a superposition of spectra of VPI-5, AlPO 4 -H 3 and SAPO-11 phases. (author). 12 refs.; 3 figs.; 1 tab

  3. MAS2-8 radar and digital control unit

    Science.gov (United States)

    Oberg, J. M.; Ulaby, F. T.

    1974-01-01

    The design of the MAS 2-8 (2 to 8 GHz microwave-active spectrometer), a ground-based sensor system, is presented. A major modification in 1974 to the MAS 2-8, that of a control subsystem to automate the data-taking operation, is the prime focus. The digital control unit automatically changes all system parameters except FM rate and records the return signal on paper tape. The overall system operation and a detailed discussion of the design and operation of the digital control unit are presented.

  4. The evolution of the MasAgro hubs

    NARCIS (Netherlands)

    Camacho-Villa, Tania Carolina; Almekinders, Conny; Hellin, Jon; Martinez-Cruz, Tania Eulalia; Rendon-Medel, Roberto; Guevara-Hernández, Francisco; Beuchelt, Tina D.; Govaerts, Bram

    2016-01-01

    Purpose: Little is known about effective ways to operationalize agricultural innovation processes. We use the MasAgro program in Mexico (which aims to increase maize and wheat productivity, profitability and sustainability), and the experiences of middle level ‘hub managers’, to understand how

  5. Angiotensin type 2 receptor (AT2R) and receptor Mas

    DEFF Research Database (Denmark)

    Villela, Daniel; Leonhardt, Julia; Patel, Neal

    2015-01-01

    The angiotensin type 2 receptor (AT2R) and the receptor Mas are components of the protective arms of the renin-angiotensin system (RAS), i.e. they both mediate tissue protective and regenerative actions. The spectrum of actions of these two receptors and their signalling mechanisms display striki...

  6. Gamma-radiation induced cross-links in ethylene-propylene rubber studied by CP-MAS NMR

    International Nuclear Information System (INIS)

    Sohma, J.; Shiotani, M.; Murakami, S.

    1983-01-01

    A new technique of 13 C-NMR, the CP-MAS method, was applied to study a chemistry of cross-links induced by #betta#-irradiation of ethylene-propylene rubber. The chemical species of cross-linking points were specified with their relative concentrations by the analysis of the CP-MAS spectra obtained before and after the irradiation. It was found that the short branches were also formed by the irradiation. A comparison was made between the cross-links detected by the CP-MAS method and those obtained by the Charlesby-Pinner analysis of the gelation caused by the #betta#-irradiation. The conventional 13 C-NMR of the cross-linked and swollen EPR provided us an information on the sol parts of the sample but little information on the cross-links in the gel parts. (author)

  7. Deuterium and lithium-6 MAS NMR studies of manganese oxide electrode materials

    Science.gov (United States)

    Paik, Younkee

    Electrolytic manganese dioxide (EMD) is used world wide as the cathode materials in both lithium and alkaline primary (non-rechargeable) batteries. We have developed deuterium and lithium MAS NMR techniques to study EMD and related manganese oxides and hydroxides, where diffraction techniques are of limited value due to a highly defective nature of the structures. Deuterons in EMD, manganite, groutite, and deuterium-intercalated pyrolusite and ramsdellite were detected by NMR, for the first time, and their locations and motions in the structures were analyzed by applying variable temperature NMR techniques. Discharge mechanisms of EMD in alkaline (aqueous) electrolytes were studied, in conjunction with step potential electrochemical spectroscopic (SPECS) method, and five distinctive discharge processes were proposed. EMD is usually heat-treated at about 300--400°C to remove water to be used in lithium batteries. Details of the effects of heat-treatment, such as structural and compositional changes as a function of heat-treatment temperature, were studied by a combination of MAS NMR, XRD, and thermogravimetric analysis. Lithium local environments in heat-treated EMD (HEMD) that were discharged in lithium cells, were described in terms of related environments found in model compounds pyrolusite and ramsdellite where specific Li + sites were detected by MAS NMR and the hyperfine shift scale method of Grey et al. Acid-leaching of Li2MnO3 represents an approach for synthesizing new or modified manganese oxide electrode materials for lithium rechargeable batteries. Progressive removal of lithium from specific crystallographic sites, followed by a gradual change of the crystal structure, was monitored by a combination of NMR and XRD techniques.

  8. To share or not to share: thats the question! When does sharing of HR services maximize perceived HR service value?

    NARCIS (Netherlands)

    Meijerink, Jeroen Gerard; Hofman, Erwin; Hemels, Hinse

    2011-01-01

    Nowadays, organizations can rely on a variety of delivery channels for offering HR services to employees, such as HR shared service centres, embedded HR professionals or electronic HRM. However, when should organizations opt for one of the many HR delivery channels that are at their disposal to

  9. Comments on H.R. 2480

    International Nuclear Information System (INIS)

    Rezendes, V.S.

    1990-10-01

    GAO testified on H.R. 2480, the Uranium Enrichment Reorganization Act, which would restructure DOE's uranium enrichment program as a government corporation. Specifically, this legislation would allow the corporation to set prices to maximize long-term returns; establish a fund to meet future decontamination, decommissioning, and remedial action costs associated with past uranium enrichment activities. and require the government to pay its share of the costs to clean up mining waste generated under past government contracts. GAO believes that H.R. 2480 takes needed steps toward establishing clear objectives for the enrichment program and would allow the new corporation to better operate as a business entity. The bill would also resolve several long-term issues that seriously challenge the program's future, including the need to pay billions of dollars in environmental and decommissioning costs at a time when competition is expected to increase. However, GAO believes that the bill could be strengthened by including a specific cost recovery provision. Because DOE projects that the corporation's future earnings could be substantial, GAO suggests that Congress require the repayment of $3 billion, rather than rely solely on unspecified dividends and/or uncertain future stock sales that may not materialize unless problems related to licensing uncertainties, increased competition, and billions of dollars in liabilities are adequately resolved

  10. International HR Strategy of Brazilian Technology Multinationals

    Directory of Open Access Journals (Sweden)

    Patricia Morilha Muritiba

    2010-10-01

    Full Text Available Four cases of Brazilian Multinationals from the information technology [IT] sector were compared in their international Human Resources strategy. The analysis is focused on the development and application of two research models. One analyzes the level of subsidiary autonomy in terms of strategic HR decisions, including difficult decisions regarding coordination in multinationals, following the theoretical approach of the autonomy of subsidiaries (Kidger, 2002; Nohria & Ghoshal, 1997. The other is related to the level of internationalization of HR strategies, defined as the capacity to take advantage of globalization, providing the best resources for the company regardless of where they are located (Sparrow, 2007. Both models were applied in a multiple case study method (Eisenhardt, 1989. Data were collected through semi-structured interviews and company reports, and analyzed through content analysis. The results show: (a a more centralizing characteristic of the multinational companies examined, despite the limitations of this choice as shown by the literature; and (b that Brazilian IT multinationals tend to rely more on their national competencies when managing human resources instead of going global to aggregate differentiated competencies.

  11. PLEIADES-HR IMAGE QUALITY COMMISSIONING

    Directory of Open Access Journals (Sweden)

    L. Lebègue

    2012-07-01

    Full Text Available PLEIADES is the highest resolution civilian earth observing system ever developed in Europe. This imagery program is conducted by the French National Space Agency, CNES. It operates since 2012 a first satellite PLEIADES-HR launched on 2011 December 17th, a second one should be launched by the end of the year. Each satellite is designed to provide optical 70 cm resolution coloured images to civilian and defence users. The Image Quality requirements were defined from users studies from the different spatial imaging applications, taking into account the trade-off between on-board technological complexity and ground processing capacity. The assessment of the image quality and the calibration operation have been performed by CNES Image Quality team during the 6 month commissioning phase that followed the satellite launch. These activities cover many topics gathered in two families : radiometric and geometric image quality. The new capabilities offered by PLEIADES-HR agility allowed to imagine new methods of image calibration and performance assessment. Starting from an overview of the satellite characteristics, this paper presents all the calibration operations that were conducted during the commissioning phase and also gives the main results for every image quality performance.

  12. THE CHARA ARRAY ANGULAR DIAMETER OF HR 8799 FAVORS PLANETARY MASSES FOR ITS IMAGED COMPANIONS

    International Nuclear Information System (INIS)

    Baines, Ellyn K.; White, Russel J.; Jones, Jeremy; Boyajian, Tabetha; McAlister, Harold A.; Ten Brummelaar, Theo A.; Turner, Nils H.; Sturmann, Judit; Sturmann, Laszlo; Goldfinger, P. J.; Farrington, Christopher D.; Riedel, Adric R.; Huber, Daniel; Ireland, Michael; Von Braun, Kaspar; Ridgway, Stephen T.

    2012-01-01

    HR 8799 is an hF0 mA5 γ Doradus-, λ Bootis-, Vega-type star best known for hosting four directly imaged candidate planetary companions. Using the CHARA Array interferometer, we measure HR 8799's limb-darkened angular diameter to be 0.342 ± 0.008 mas (an error of only 2%). By combining our measurement with the star's parallax and photometry from the literature, we greatly improve upon previous estimates of its fundamental parameters, including stellar radius (1.44 ± 0.06 R ☉ ), effective temperature (7193 ± 87 K, consistent with F0), luminosity (5.05 ± 0.29 L ☉ ), and the extent of the habitable zone (HZ; 1.62-3.32 AU). These improved stellar properties permit much more precise comparisons with stellar evolutionary models, from which a mass and age can be determined, once the metallicity of the star is known. Considering the observational properties of other λ Bootis stars and the indirect evidence for youth of HR 8799, we argue that the internal abundance, and what we refer to as the effective abundance, is most likely near solar. Finally, using the Yonsei-Yale evolutionary models with uniformly scaled solar-like abundances, we estimate HR 8799's mass and age considering two possibilities: 1.516 +0.038 –0.024 M ☉ and 33 +7 –13.2 Myr if the star is contracting toward the zero-age main sequence or 1.513 +0.023 –0.024 M ☉ and 90 +381 –50 Myr if it is expanding from it. This improved estimate of HR 8799's age with realistic uncertainties provides the best constraints to date on the masses of its orbiting companions, and strongly suggests they are indeed planets. They nevertheless all appear to orbit well outside the HZ of this young star.

  13. ERP sistēmas ieviešana

    OpenAIRE

    Proskurins, Aleksandrs

    2008-01-01

    Šajā darbā tika apskatīta informācijas sistēmu klasifikācija, uzņēmuma resursu plānošanas sistēmas (ERP) definīcija un tās vieta IS klasifikācijā. Tika apskatīti ERP sistēmu ieviešanas teorētiskie aspekti, izstrādes un pielāgošanas specifika, kā arī tika izanalizēti vairāki ERP sistēmas ieviešanas projekti Latvijas uzņēmumos.

  14. Global trends and challenges to the HR profession.

    OpenAIRE

    Prouska, Rea; Cooke, Fang Lee.

    2006-01-01

    The outsourcing of HR activities is a management strategy that may be adopted in response to a number of pressures that an organization is faced with. It is one aspect of business process outsourcing that is increasingly deployed by firms in order to enhance their organizational competitiveness. HR outsourcing can be defined as ‘placing responsibility for various elements of the HR function with a third-party provider’ (Turnbull, 2002, p.11). In spite of the perceived benefits of HR outsourci...

  15. Learning and Development Policy available on HR web

    CERN Multimedia

    2012-01-01

    The full text of CERN’s “Learning and Development Policy” is now available in English and French on the HR training website: cern.ch/hr-training/. This new policy was presented to all personnel in the HR Public meeting held on Monday 25 June, and the slides and the video recording remain available on Indico. Pascale Goy, Head of the Learning and Development Group in HR, is available for more information: pascale.goy@cern.ch , tel. 62232.

  16. FACILITATING RADICAL FRONT-END INNOVATION THROUGH TARGETED HR PRACTICES

    DEFF Research Database (Denmark)

    Aagaard, Annabeth

    2017-01-01

    This study examines how radical front end innovation can be actively facilitated through selected and targeted HR practices and bundles of HR practices. The empirical field is an explorative case study of front end innovation and HR practices in the pharmaceutical industry, with an in-depth case ...

  17. ATTITUDE ASSESSMENT USING PLEIADES-HR CAPABILITIES

    Directory of Open Access Journals (Sweden)

    J. M. Delevit

    2012-07-01

    Full Text Available Since SPOT1, the French national space centre (CNES has worked on improving the geometry of Earth observation spacecrafts. The accuracy of sensor calibration is one of the main key points for any Earth observation application such as orthorectification, DEM generation or surface change detection. For the last twenty years CNES has developed two families of methods: absolute methods and relative methods. These methods are used to characterize a pushbroom acquisition along the detector line and the time line. By this way, the viewing directions are measured and the residual of the spacecraft’s attitude angles (not restituted by the Attitude and Orbit Control System is estimated. This information can complete the geometric model of all the scenes acquired by the instrument and is used in all geometric applications. This paper presents new attitude assessment methods taking advantage of the capabilities of Pléiades-HR in terms of agility and focal plane arrangement – panchromatic band and multispectral (MS bands.

  18. Measuring proton shift tensors with ultrafast MAS NMR.

    Science.gov (United States)

    Miah, Habeeba K; Bennett, David A; Iuga, Dinu; Titman, Jeremy J

    2013-10-01

    A new proton anisotropic-isotropic shift correlation experiment is described which operates with ultrafast MAS, resulting in good resolution of isotropic proton shifts in the detection dimension. The new experiment makes use of a recoupling sequence designed using symmetry principles which reintroduces the proton chemical shift anisotropy in the indirect dimension. The experiment has been used to measure the proton shift tensor parameters for the OH hydrogen-bonded protons in tyrosine·HCl and citric acid at Larmor frequencies of up to 850 MHz. Copyright © 2013 Elsevier Inc. All rights reserved.

  19. A General Protocol for Temperature Calibration of MAS NMR Probes at Arbitrary Spinning Speeds

    Science.gov (United States)

    Guan, Xudong; Stark, Ruth E.

    2010-01-01

    A protocol using 207Pb NMR of solid lead nitrate was developed to determine the temperature of magic-angle spinning (MAS) NMR probes over a range of nominal set temperatures and spinning speeds. Using BioMAS and fastMAS probes with typical sample spinning rates of 8 and 35 kHz, respectively, empirical equations were devised to predict the respective sample temperatures. These procedures provide a straightforward recipe for temperature calibration of any MAS probe. PMID:21036557

  20. What drives cross-border M&As in commercial banking?

    NARCIS (Netherlands)

    Galamhussen, Mohamed; Hennart, Jean-Francois; Pinheiro, Carlos Manuel

    2016-01-01

    Using a gravity model, we analyze the determinants of the probability that commercial banks in 89 acquiring countries and 118 target countries will undertake M&As over a 30-year period (1981–2010) and of the value of these M&As. We find that the value of cross-border M&As increases with the size of

  1. Radiofrequency fields in MAS solid state NMR probes

    Science.gov (United States)

    Tošner, Zdeněk; Purea, Armin; Struppe, Jochem O.; Wegner, Sebastian; Engelke, Frank; Glaser, Steffen J.; Reif, Bernd

    2017-11-01

    We present a detailed analysis of the radiofrequency (RF) field over full volume of a rotor that is generated in a solenoid coil. On top of the usually considered static distribution of amplitudes along the coil axis we describe dynamic radial RF inhomogeneities induced by sample rotation. During magic angle spinning (MAS), the mechanical rotation of the sample about the magic angle, a spin packet travels through areas of different RF fields and experiences periodical modulations of both the RF amplitude and the phase. These modulations become particularly severe at the end regions of the coil where the relative RF amplitude varies up to ±25% and the RF phase changes within ±30°. Using extensive numerical simulations we demonstrate effects of RF inhomogeneity on pulse calibration and for the ramped CP experiment performed at a wide range of MAS rates. In addition, we review various methods to map RF fields using a B0 gradient along the sample (rotor axis) for imaging purposes. Under such a gradient, a nutation experiment provides directly the RF amplitude distribution, a cross polarization experiment images the correlation of the RF fields on the two channels according to the Hartmann-Hahn matching condition, while a spin-lock experiment allows to calibrate the RF amplitude employing the rotary resonance recoupling condition. Knowledge of the RF field distribution in a coil provides key to understand its effects on performance of a pulse sequence at the spectrometer and enables to set robustness requirements in the experimental design.

  2. Influence of using high kV and low m As techniques in the dose of patients submitted to X ray thorax examinations; Influencia do uso de tecnicas de alto kV e baixo mAs na dose em pacientes submetidos a exames de raios X de torax

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Paulo Marcio Campos de, E-mail: pmco@cdtn.b [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Dept. de Engenharia Nuclear. Programa de Pos-Graduacao em Ciencias e Tecnicas Nucleares; Squair, Peterson Lima; Lacerda, Marco Aurelio de Sousa; Silva, Teogenes Augusto da, E-mail: pls@cdtn.b, E-mail: masl@cdtn.b, E-mail: silvata@cdtn.b [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2011-07-01

    Dosimetric studies of patients subject to radiodiagnostic have got a special attention in Brazil although they are not required by the Brazilian legislation. However, in several Brazilian clinics there have been observed the use of techniques with lower peak voltage and higher electric charges values in spite the European Commission recommends the high voltages with low electric charge values in order to reduce the patient dose. This work compares three methodologies for evaluating the organ absorbed doses in patients undergoing chest x-rays at two techniques (80 k Vp and 10 m As; 120 k Vp and 2 m As): the PCXMC and CALDose{sub X} Monte Carlo based software and experimental measurements with T L dosimeters in a anthropomorphic phantom. The experimental measurements showed the technique with high voltage was dose reduced by approximately 60% in the entrance skin in relation to low voltage technique and the software showed similar dose reduction, shows the importance of adopting techniques which have high voltage values and low electrical charges, unlike usually found on chest x-rays in some hospitals and clinics in Brazil. (author)

  3. Genotyping by sequencing (GBS, an ultimate marker-assisted selection (MAS tool to accelerate plant breeding

    Directory of Open Access Journals (Sweden)

    Jiangfeng eHe

    2014-09-01

    Full Text Available Marker-assisted selection (MAS refers to the use of molecular markers to assist phenotypic selections in crop improvement. Several types of molecular markers, such as single nucleotide polymorphism (SNP, have been identified and effectively used in plant breeding. The application of next-generation sequencing (NGS technologies has led to remarkable advances in whole genome sequencing, which provides ultra-throughput sequences to revolutionize plant genotyping and breeding. To further broaden NGS usages to large crop genomes such as maize and wheat, genotyping by sequencing (GBS has been developed and applied in sequencing multiplexed samples that combine molecular marker discovery and genotyping. GBS is a novel application of NGS protocols for discovering and genotyping SNPs in crop genomes and populations. The GBS approach includes the digestion of genomic DNA with restriction enzymes followed by the ligation of barcode adapter, PCR amplification and sequencing of the amplified DNA pool on a single lane of flow cells. Bioinformatic pipelines are needed to analyze and interpret GBS datasets. As an ultimate MAS tool and a cost-effective technique, GBS has been successfully used in implementing genome-wide association study (GWAS, genomic diversity study, genetic linkage analysis, molecular marker discovery and genomic selection (GS under a large scale of plant breeding programs.

  4. Calcium isotope measurement by combined HR-MC-ICPMS and TIMS

    DEFF Research Database (Denmark)

    Schiller, Martin; Paton, Chad; Bizzarro, Martin

    2012-01-01

    studies demonstrate that it is possible to measure the mass-dependent Ca isotope composition of terrestrial materials using HR-MC-ICPMS with an external reproducibility comparable to that typically obtained with double spike TIMS techniques. The resolution of the mass-independent 43Ca, 46Ca and 48Ca data...

  5. The MAS Six Years in Power in Bolivia

    Directory of Open Access Journals (Sweden)

    Ton Salman

    2012-04-01

    Full Text Available Review Essay of:– The Rise of Evo Morales and the MAS, by Sven Harten. London/New York: Zed Books, 2011.– Evo Morales and the Movimiento al Socialismo in Bolivia; The First Term in Context, edited by Adrian J. Pearce. London, Institute for the Study of the Americas, 2011.– El estado de derecho como tiranía, by Luis Tapia. La Paz: CIDES/UMSA, 2011.– From Rebellion to Reform in Bolivia: Class Struggle, Indigenous Liberation and the Politics of Evo Morales, by Jeffery R. Webber. Chicago: Haymarket Books, 2011.– La democracia desde los márgenes: Transformaciones en el campo político boliviano, by María Teresa Zegada, with Claudia Arce, Gabriela Canedo and Alber Quispe. La Paz: Muela del Diablo Editores/CLACSO, 2011.

  6. TOKSISITAS LETAL MOLUSKISIDA NIKLOSAMIDA PADA BENIH IKAN MAS (Cyprinus carpio

    Directory of Open Access Journals (Sweden)

    Yosmaniar Yosmaniar

    2009-04-01

    Full Text Available Penggunaan moluskisida untuk menanggulangi hama dalam budidaya tanaman padi yang semakin meningkat berpotensi mencemari lingkungan perairan, karena mengandung residu dari bahan aktifnya. Moluskisida niklosamida (C13H8Cl2N2O4 merupakan bahan aktif pestisida yang digunakan untuk memberantas hama keong mas atau siput murbei (Pomacea sp. di sawah. Dengan demikian, bahan tersebut memiliki potensi untuk mencemari lahan tempat usaha budidaya ikan. Penelitian ini bertujuan untuk mengetahui potensi toksisitas akut niklosamida terhadap benih ikan mas (Cyprinus carpio yang ditunjukkan oleh nilai Median Lethal Concentration (LC50 24, 48, dan 96 jam. Penelitian dilakukan di Instalasi Riset Lingkungan Perikanan Budidaya dan Toksikologi, Cibalagung-Bogor. Menggunakan ikan mas dengan bobot individu 2,47 ± 0,13 g. Moluskisida yang digunakan mengandung bahan aktif niklosamida 250g/L. Wadah pengujian berupa 21 unit akuarium kaca berukuran 40 cm x 20 cm x 20 cm yang dilengkapi aerasi serta saluran pemasukan dan pengeluaran. Jumlah ikan uji setiap wadah 10 ekor dengan peubah yang diukur adalah mortalitas ikan. Selama penelitian ikan tidak diberi makan. Tahapan penelitian terdiri atas penentuan nilai ambang atas-bawah, nilai lethal time dan LC50 -24, 48, 72, dan 96 jam. Data diolah dengan analisis probit program LC50. Hasil penelitian menunjukkan bahwa nilai LC50-24, 48, 72, dan 96 jam terhadap benih ikan mas adalah 0,8012 (0,7140—0,8990; 0,5999 (0,5356—0,6719; 0,4511 (0,4067—0,5004; dan 0,3849 mg/L (0,3684—0,4061. Hal ini menunjukkan niklosamida termasuk pestisida yang memiliki toksisitas sangat tinggi (golongan A. The use of molluscicide in aquatic as well as in terresterial agro ecosystem without properly controlled may produce detrimental effects on freshwater fisheries. Molluscicide utilization for golden apple snail (Pomacea sp. control in rice field has increased. The ingredient potencially has a possibility to pollute aquaculture water. The

  7. Food Waste Composting Study from Makanan Ringan Mas

    Science.gov (United States)

    Kadir, A. A.; Ismail, S. N. M.; Jamaludin, S. N.

    2016-07-01

    The poor management of municipal solid waste in Malaysia has worsened over the years especially on food waste. Food waste represents almost 60% of the total municipal solid waste disposed in the landfill. Composting is one of low cost alternative method to dispose the food waste. This study is conducted to compost the food waste generation in Makanan Ringan Mas, which is a medium scale industry in Parit Kuari Darat due to the lack knowledge and exposure of food waste recycling practice. The aim of this study is to identify the physical and chemical parameters of composting food waste from Makanan Ringan Mas. The physical parameters were tested for temperature and pH value and the chemical parameter are Nitrogen, Phosphorus and Potassium. In this study, backyard composting was conducted with 6 reactors. Tapioca peel was used as fermentation liquid and soil and coconut grated were used as the fermentation bed. Backyard composting was conducted with six reactors. The overall results from the study showed that the temperature of the reactors were within the range which are from 30° to 50°C. The result of this study revealed that all the reactors which contain processed food waste tend to produce pH value within the range of 5 to 6 which can be categorized as slightly acidic. Meanwhile, the reactors which contained raw food waste tend to produce pH value within the range of 7 to 8 which can be categorized as neutral. The highest NPK obtained is from Reactor B that process only raw food waste. The average value of Nitrogen is 48540 mg/L, Phosphorus is 410 mg/L and Potassium is 1550 mg/L. From the comparison with common chemical fertilizer, it shows that NPK value from the composting are much lower than NPK of the common chemical fertilizer. However, comparison with NPK of organic fertilizer shown only slightly difference value in NPK.

  8. Antioxidant capacity of cornelian cherry (Cornus mas L.) - comparison between permanganate reducing antioxidant capacity and other antioxidant methods.

    Science.gov (United States)

    Popović, Boris M; Stajner, Dubravka; Slavko, Kevrešan; Sandra, Bijelić

    2012-09-15

    Ethanol extracts (80% in water) of 10 cornelian cherry (Cornus mas L.) genotypes were studied for antioxidant properties, using methods including DPPH(), ()NO, O(2)(-) and ()OH antiradical powers, FRAP, total phenolic and anthocyanin content (TPC and ACC) and also one relatively new, permanganate method (permanganate reducing antioxidant capacity-PRAC). Lipid peroxidation (LP) was also determined as an indicator of oxidative stress. The data from different procedures were compared and analysed by multivariate techniques (correlation matrix calculation and principal component analysis (PCA)). Significant positive correlations were obtained between TPC, ACC and DPPH(), ()NO, O(2)(-), and ()OH antiradical powers, and also between PRAC and TPC, ACC and FRAP. PCA found two major clusters of cornelian cherry, based on antiradical power, FRAP and PRAC and also on chemical composition. Chemometric evaluation showed close interdependence between PRAC method and FRAP and ACC. There was a huge variation between C. mas genotypes in terms of antioxidant activity. Copyright © 2012 Elsevier Ltd. All rights reserved.

  9. Peptide-Based Membrane Fusion Inhibitors Targeting HCoV-229E Spike Protein HR1 and HR2 Domains

    Directory of Open Access Journals (Sweden)

    Shuai Xia

    2018-02-01

    Full Text Available Human coronavirus 229E (HCoV-229E infection in infants, elderly people, and immunocompromised patients can cause severe disease, thus calling for the development of effective and safe therapeutics to treat it. Here we reported the design, synthesis and characterization of two peptide-based membrane fusion inhibitors targeting HCoV-229E spike protein heptad repeat 1 (HR1 and heptad repeat 2 (HR2 domains, 229E-HR1P and 229E-HR2P, respectively. We found that 229E-HR1P and 229E-HR2P could interact to form a stable six-helix bundle and inhibit HCoV-229E spike protein-mediated cell-cell fusion with IC50 of 5.7 and 0.3 µM, respectively. 229E-HR2P effectively inhibited pseudotyped and live HCoV-229E infection with IC50 of 0.5 and 1.7 µM, respectively. In a mouse model, 229E-HR2P administered intranasally could widely distribute in the upper and lower respiratory tracts and maintain its fusion-inhibitory activity. Therefore, 229E-HR2P is a promising candidate for further development as an antiviral agent for the treatment and prevention of HCoV-229E infection.

  10. Designing HR Organizational Structures in terms of the HR Business Partner Model Principles from the Perspective of Czech Organizations

    Directory of Open Access Journals (Sweden)

    Marek Stříteský

    2014-03-01

    Full Text Available This paper describes new trends related to the concepts contained in HR organizational structures within Czech organizations. In addition, it describes the specifics of the roles played by HR in those organizations which have transformed their HR departments in terms of the principles of the HR Business Partner Model, both in theory based on available resources, and at the practical level based on the results of primary examination. The goal of this paper is to present the key perceptions of the changes made in the HR structure within the organizations, as well as the impact of these changes on the effectiveness of the HR departments concerned. Another goal of the paper is to summarize the responsibilities of the newly created position known as the HR Business Partner in these organizations as well as the demands placed upon the personnel employed in the HR Business Partner role. The paper offers conclusions based on the results of both quantitative and qualitative surveys. It also contains a case study of one organization which has one of the best transformed HR departments, and whose services are classified, by internal clients, as being of high quality.

  11. Angiotensin-(1-7)/Mas axis integrity is required for the expression of object recognition memory.

    Science.gov (United States)

    Lazaroni, Thiago L N; Raslan, Ana Cláudia S; Fontes, Walkiria R P; de Oliveira, Marilene L; Bader, Michael; Alenina, Natalia; Moraes, Márcio F D; Dos Santos, Robson A; Pereira, Grace S

    2012-01-01

    It has been shown that the brain has its own intrinsic renin-angiotensin system (RAS) and angiotensin-(1-7) (Ang-(1-7)) is particularly interesting, because it appears to counterbalance most of the Ang II effects. Ang-(1-7) exerts its biological function through activation of the G-protein-coupled receptor Mas. Interestingly, hippocampus is one of the regions with higher expression of Mas. However, the role of Ang-(1-7)/Mas axis in hippocampus-dependent memories is still poorly understood. Here we demonstrated that Mas ablation, as well as the blockade of Mas in the CA1-hippocampus, impaired object recognition memory (ORM). We also demonstrated that the blockade of Ang II receptors AT1, but not AT2, recovers ORM impairment of Mas-deficient mice. Considering that high concentrations of Ang-(1-7) may activate AT1 receptors, nonspecifically, we evaluate the levels of Ang-(1-7) and its main precursors Ang I and Ang II in the hippocampus of Mas-deficient mice. The Ang I and Ang II levels are unaltered in the whole hipocampus of MasKo. However, Ang-(1-7) concentration is increased in the whole hippocampus of MasKo mice, as well as in the CA1 area. Taken together, our findings suggest that the functionality of the Ang-(1-7)/Mas axis is essential for normal ORM processing. Copyright © 2011 Elsevier Inc. All rights reserved.

  12. HR competencies at a merged Higher Education Institution

    Directory of Open Access Journals (Sweden)

    Cecile M. Schultz

    2010-06-01

    Research purposes: The aim of this study was to determine the HR competencies at a merged higher education institution. Other objectives were to establish the satisfaction of academics, administrative staff and management regarding the HR competencies and the importance thereof. Motivation for the study: Human resource professionals require assistance by providing HR competencies necessary to add value at a merged higher education institution. Research designs, approaches and methods: A quantitative research design was employed as the research strategy. The questionnaire was based on the literature, the business plan and the HR balanced scorecard report. The target population was 1363 permanent staff on one campus and the response rate was 28%. A principal factor analysis, spider charts and box plots were utilised for data analysis. The results indicated business knowledge, HR practices, personal skills and management skills as the vital HR competencies. Practical implications: Staff were not satisfied with the current HR competencies and consequently this necessitated attention to improve the deficient areas. Contribution: This study shows that limited research was done with regard to HR competencies in the South African higher education backdrop.

  13. Managing (Sales)People towards Performance: HR Strategy, Leadership & Teamwork

    NARCIS (Netherlands)

    H.M.S. Dietz (Bart)

    2009-01-01

    textabstractManaging people towards performance is one of the most critical priorities for managers in practice. This dissertation focuses on this important issue and explores how HR Strategy, Leaders, and Teams, impact performance. It addresses respectively how HR as a system of coherent

  14. Value creation through HR shared services: towards a conceptual framework

    NARCIS (Netherlands)

    Meijerink, Jeroen Gerard; Bondarouk, Tatiana; Looise, Jan C.

    2013-01-01

    Purpose – The purpose of this paper is to derive a measure for the performance of human resource shared service providers (HR SSPs) and then to develop a theoretical framework that conceptualises their performance. Design/methodology/approach – This conceptual paper starts from the HR shared

  15. Outsourcing HR Services: The Role of Human Resource Intermediaries

    Science.gov (United States)

    Kock, Henrik; Wallo, Andreas; Nilsson, Barbro; Hoglund, Cecilia

    2012-01-01

    Purpose: In this article, the area of interest is an emerging type of organisation called human resource intermediaries (HRIs), which focus on delivering human resource (HR) services to public sector organisations and private companies. The purpose of this article is, thus, to explore HRIs as deliverers of HR services. More specifically, the…

  16. Professional Development of HR Practitioners--A Phenomenographic Study

    Science.gov (United States)

    Bailey, Moira

    2015-01-01

    Purpose: The purpose of this paper is an investigation into the experiences of professional development of human resource (HR) practitioners in the North of Scotland, and the use of non-formal learning in that development. Design/methodology/approach: In-depth semi-structured interviews from a purposively selected sample of HR practitioners were…

  17. African American Accounting Majors and the 150-hr Requirement

    Science.gov (United States)

    Booker, Quinton; Hill, Cecil L.; Wright, Carl

    2010-01-01

    The study provides information on African American accounting majors' views regarding 150-hr issues. The authors collected data from 152 students at two schools. Students at one school supported the requirement while those at the other school did not. However, students believed that the 150-hr requirement enhances the quality of certified public…

  18. Evidence for Heterodimerization and Functional Interaction of the Angiotensin Type 2 Receptor and the Receptor MAS.

    Science.gov (United States)

    Leonhardt, Julia; Villela, Daniel C; Teichmann, Anke; Münter, Lisa-Marie; Mayer, Magnus C; Mardahl, Maibritt; Kirsch, Sebastian; Namsolleck, Pawel; Lucht, Kristin; Benz, Verena; Alenina, Natalia; Daniell, Nicholas; Horiuchi, Masatsugu; Iwai, Masaru; Multhaup, Gerhard; Schülein, Ralf; Bader, Michael; Santos, Robson A; Unger, Thomas; Steckelings, Ulrike Muscha

    2017-06-01

    The angiotensin type 2 receptor (AT2R) and the receptor MAS are receptors of the protective arm of the renin-angiotensin system. They mediate strikingly similar actions. Moreover, in various studies, AT2R antagonists blocked the effects of MAS agonists and vice versa. Such cross-inhibition may indicate heterodimerization of these receptors. Therefore, this study investigated the molecular and functional interplay between MAS and the AT2R. Molecular interactions were assessed by fluorescence resonance energy transfer and by cross correlation spectroscopy in human embryonic kidney-293 cells transfected with vectors encoding fluorophore-tagged MAS or AT2R. Functional interaction of AT2R and MAS was studied in astrocytes with CX3C chemokine receptor-1 messenger RNA expression as readout. Coexpression of fluorophore-tagged AT2R and MAS resulted in a fluorescence resonance energy transfer efficiency of 10.8 ± 0.8%, indicating that AT2R and MAS are capable to form heterodimers. Heterodimerization was verified by competition experiments using untagged AT2R and MAS. Specificity of dimerization of AT2R and MAS was supported by lack of dimerization with the transient receptor potential cation channel, subfamily C-member 6. Dimerization of the AT2R was abolished when it was mutated at cysteine residue 35. AT2R and MAS stimulation with the respective agonists, Compound 21 or angiotensin-(1-7), significantly induced CX3C chemokine receptor-1 messenger RNA expression. Effects of each agonist were blocked by an AT2R antagonist (PD123319) and also by a MAS antagonist (A-779). Knockout of a single of these receptors made astrocytes unresponsive for both agonists. Our results suggest that MAS and the AT2R form heterodimers and that-at least in astrocytes-both receptors functionally depend on each other. © 2017 American Heart Association, Inc.

  19. Distributed Cooperation Solution Method of Complex System Based on MAS

    Science.gov (United States)

    Weijin, Jiang; Yuhui, Xu

    To adapt the model in reconfiguring fault diagnosing to dynamic environment and the needs of solving the tasks of complex system fully, the paper introduced multi-Agent and related technology to the complicated fault diagnosis, an integrated intelligent control system is studied in this paper. Based on the thought of the structure of diagnostic decision and hierarchy in modeling, based on multi-layer decomposition strategy of diagnosis task, a multi-agent synchronous diagnosis federation integrated different knowledge expression modes and inference mechanisms are presented, the functions of management agent, diagnosis agent and decision agent are analyzed, the organization and evolution of agents in the system are proposed, and the corresponding conflict resolution algorithm in given, Layered structure of abstract agent with public attributes is build. System architecture is realized based on MAS distributed layered blackboard. The real world application shows that the proposed control structure successfully solves the fault diagnose problem of the complex plant, and the special advantage in the distributed domain.

  20. Multi-Robot Remote Interaction with FS-MAS

    Directory of Open Access Journals (Sweden)

    Yunliang Jiang

    2013-02-01

    Full Text Available The need to reduce bandwidth, improve productivity, autonomy and the scalability in multi-robot teleoperation has been recognized for a long time. In this article we propose a novel finite state machine mobile agent based on the network interaction service model, namely FS-MAS. This model consists of three finite state machines, namely the Finite State Mobile Agent (FS-Agent, which is the basic service module. The Service Content Finite State Machine (Content-FS, using the XML language to define workflow, to describe service content and service computation process. The Mobile Agent computation model Finite State Machine (MACM-FS, used to describe the service implementation. Finally, we apply this service model to the multi-robot system, the initial realization completing complex tasks in the form of multi-robot scheduling. This demonstrates that the robot has greatly improved intelligence, and provides a wide solution space for critical issues such as task division, rational and efficient use of resource and multi-robot collaboration.

  1. PEMANFAATAN TANAMAN ATRAKTAN MENGENDALIKAN HAMA KEONG MAS PADI

    Directory of Open Access Journals (Sweden)

    Ameilia Zuliyanti Siregar

    2018-01-01

    In Indonesia, many plantation as use as beneficial plants. This study aims to obtain an effective formula that can be used as a biopesticide to control snail pests during the vegetative phase from May to July 2017 using random non-factorial methods at two rice planting locations in the Village Lae parira, Dairi, North Sumatra. Design with 6 treatments and 3 replicates (ie control, neem leaves (Azadirachta indica, tobacco leaf (Nicotiana tabacum, sweet potato leaf (Manihot glaziovii, noni fruit, Morinda citrifolia, and betel nut (Areca catechu and papaya (Carica papaya as an eco-friendly herbaceous and biopesticide. Based on the study recorded in sampling for 7 days with 6 treatments had significant effect on the percentage affected by the clump of rice attacked and the percentage of death. Pearson correlation value recorded percentage of death and percentage of impacted  showed a very significant relationship. Neem is the best biopesticide in controlling mollusicides, followed by betel nuts, tobacco, poisonous yams and noni. Death of 100% snail mas will prevent damage to the clump of rice plants Dairi, North Sumatra. All biopesticide treatments were tested to control snail pests in rice plants that will increase agicultural productivity in maintaining food security in Dairi, North Sumatra.

  2. Local environments and lithium adsorption on the iron oxyhydroxides lepidocrocite (gamma-FeOOH) and goethite (alpha-FeOOH): A 2H-2 and 7Li solid-state MAS NMR study

    DEFF Research Database (Denmark)

    Nielsen, Ulla Gro; Grey, Clare P.; Paik, Jonkim

    2008-01-01

    2H and 7LiMAS NMR spectroscopy techniques were applied to study the local surface and bulk environments of iron oxyhydroxide lepiclocrocite (gamma-FeOOH). 2H variable-temperature (VT) MAS NMR experiments were performed, showing the presence of short-range, strong antiferromagnetic correlations......, even at temperatures above the Neel temperature, TN, 77 K. The formation of a Li+ inner-sphere complex on the surface of lepiclocrocite was confirmed by the observation of a signal with a large 7Li hyperfine shift in the 7Li  MAS NMR spectrum. The effect of pH and relative humidity (RH...

  3. Employee Work-Life Balance as an HR Imperative | Igbinomwanhia ...

    African Journals Online (AJOL)

    Employee Work-Life Balance as an HR Imperative. ... With the growing diversity of family structures represented in today‟s workforce, ... of managing an employee's work-life balance have increased markedly over the past 20 years.

  4. HR practices for enhancing sustainable employability : implementation, use, and outcomes

    OpenAIRE

    Ybema, Jan Fekke; van Vuuren, Tinka; van Dam, Karen

    2017-01-01

    With the aging of the workforce, organizations need to maintain or improve the sustainable employability of their workforce throughout their working life. This raises the question which HR practices increase workers’ sustainable employability at work. The aim of this study is to investigate the extent to which organizations implement HR practices for enhancing sustainable employability in terms of workers’ health, motivation, and skills and knowledge from the employer’s perspective. In total,...

  5. E/Z MAS: An easy-to-use computerized materials control and accountability system

    International Nuclear Information System (INIS)

    Anderson, L.K.; Boor, M.G.; Hurford, J.M.; Landry, R.P.; Martinez, B.J.; Solem, A.M.; Whiteson, R.; Zardecki, A.

    1998-01-01

    Nuclear facilities that handle and process nuclear materials are required to track their nuclear holdings and to keep adequate records that manage and control the inventory of those holdings. The complexity of a system that does this job is directly proportional to the complexity of the facility's operations. This paper describes an approach to computerized materials protection, control, and accountability (MPC and A) that was introduced by Los Alamos National Laboratory (LANL) in the fall of 1997. This new system, E/Z MAS, is the latest addition to the LANL suite of computerized MPC and A tools, which also includes the CoreMAS system. E/Z MAS was initially designed to address the needs of those facilities that have small to modest MPC and A needs but has been expanded to provide full functionality for any facility. The system name, E/Z MAS, reflects the system's easy-to-use characteristics, which include ease of installation and ease of software maintenance. Both CoreMAS and E/Z MAS have been provided to facilities in the Former Soviet Union to assist them in implementing a computerized MPC and A system that meets their needs. In this paper the authors will address the functionality of CoreMAS and E/Z MAS, and an argument in favor of intranet-based material control and accountability will be advanced

  6. Evidence for Heterodimerization and Functional Interaction of the Angiotensin Type 2 Receptor and the Receptor MAS

    DEFF Research Database (Denmark)

    Leonhardt, Julia; Villela, Daniel C.; Teichmann, Anke

    2017-01-01

    The angiotensin type 2 receptor (AT2R) and the receptor MAS are receptors of the protective arm of the renin-angiotensin system. They mediate strikingly similar actions. Moreover, in various studies, AT2R antagonists blocked the effects of MAS agonists and vice versa. Such cross-inhibition may in...

  7. Angiotensin-(1-7)/Mas axis modulates fear memory and extinction in mice.

    Science.gov (United States)

    Lazaroni, Thiago Luiz do Nascimento; Bastos, Cristiane Perácio; Moraes, Márcio Flávio Dutra; Santos, Robson Souza; Pereira, Grace Schenatto

    2016-01-01

    Inappropriate defense-alerting reaction to fear is a common feature of neuropsychiatric diseases. Therefore, impairments in brain circuits, as well as in molecular pathways underlying the neurovegetative adjustments to fear may play an essential role on developing neuropsychiatric disorders. Here we tested the hypothesis that interfering with angiotensin-(1-7) [Ang-(1-7)]/Mas receptor axis homeostasis, which appears to be essential to arterial pressure control, would affect fear memory and extinction. Mas knockout (MasKO) mice, in FVB/N background, showed normal cued fear memory and extinction, but increased freezing in response to context. Next, as FVB/N has poor performance in contextual fear memory, we tested MasKO in mixed 129xC57BL/6 background. MasKO mice behaved similarly to wild-type (WT), but memory extinction was slower in contextual fear conditioning to a weak protocol (1CS/US). In addition, delayed extinction in MasKO mice was even more pronounced after a stronger protocol (3CS/US). We showed previously that Angiotensin II receptor AT1 antagonist, losantan, rescued object recognition memory deficit in MasKO mice. Here, losartan was also effective. Memory extinction was accelerated in MasKO mice after treatment with losartan. In conclusion, we showed for the first time that Ang-(1-7)/Mas axis may modulate fear memory extinction. Furthermore, we suggest MasKO mice as an animal model to study post-traumatic stress disorder (PTSD). Copyright © 2015 Elsevier Inc. All rights reserved.

  8. A nonlinear filtering algorithm for denoising HR(S)TEM micrographs

    International Nuclear Information System (INIS)

    Du, Hongchu

    2015-01-01

    Noise reduction of micrographs is often an essential task in high resolution (scanning) transmission electron microscopy (HR(S)TEM) either for a higher visual quality or for a more accurate quantification. Since HR(S)TEM studies are often aimed at resolving periodic atomistic columns and their non-periodic deviation at defects, it is important to develop a noise reduction algorithm that can simultaneously handle both periodic and non-periodic features properly. In this work, a nonlinear filtering algorithm is developed based on widely used techniques of low-pass filter and Wiener filter, which can efficiently reduce noise without noticeable artifacts even in HR(S)TEM micrographs with contrast of variation of background and defects. The developed nonlinear filtering algorithm is particularly suitable for quantitative electron microscopy, and is also of great interest for beam sensitive samples, in situ analyses, and atomic resolution EFTEM. - Highlights: • A nonlinear filtering algorithm for denoising HR(S)TEM images is developed. • It can simultaneously handle both periodic and non-periodic features properly. • It is particularly suitable for quantitative electron microscopy. • It is of great interest for beam sensitive samples, in situ analyses, and atomic resolution EFTEM

  9. News from HR: a word from Anne-Sylvie Catherin

    CERN Multimedia

    2016-01-01

    Anne-Sylvie Catherin, head of HR Department, looks back over her years at CERN before taking up her new position at the European Central Bank.   At the end of July, I will be leaving CERN on a special leave of absence to take up a new position at the European Central Bank. This is a new chapter in my career, in a new context with its own challenges, and as I prepare for it, I would like to take a little time to look back over my years at CERN and share with you the enriching journey it has been, both for myself and for HR. It has always been my strong belief that any organisation’s greatest asset is its people. When an HR professional believes that, it’s only a short step to the conclusion that the best way to nurture those people is by adopting a professional approach to HR. In this respect, I arrived at a very fortuitous time. Enrico Chiaveri was head of HR and, although his background is in physics, we shared that same conviction. Enrico was the icebreaker in driving change, a...

  10. The Link between HR Attributions and Employees’ Turnover Intentions

    Directory of Open Access Journals (Sweden)

    Juliana Caesaria Tandung

    2016-02-01

    Full Text Available Human Resources Management (HRM is part of the organizational functions that contribute to the effectiveness of a firm’s performance, and brings an organization a competitive advantage through the implementation of its Human Resources (HR practices. HR practices adopted by management are perceived or attributed subjectively by individual employees, and can in turn affect the employees’ attitudes and behavior (e.g. Job satisfaction and turnover intention. The purpose of this study is to contribute to the process-based approach by investigating the effect of HR attributions on turnover intentions, with job satisfaction playing a mediating role. The analysis is on the individual level, with 454 respondents from various organizations within the Netherlands. The results show that HR attributions can affect the turnover intention, through the presence of job satisfaction. Thus, it can be said that it is important to always consider the employees’ attitudes and behavior when examining their perception of HR practices, and in predicting their intention to leave.

  11. Residue specific hydration of primary cell wall potato pectin identified by solid-state 13C single-pulse MAS and CP/MAS NMR spectroscopy

    DEFF Research Database (Denmark)

    Larsen, Flemming Hofmann; Chrestensen, Inge Byg; Damager, Iben

    2011-01-01

    Hydration of rhamnogalacturonan-I (RG-I) derived from potato cell wall was analyzed by 13C single-pulse (SP) magic-angle-spinning (MAS) and 13C cross-polarization (CP) MAS nuclear magnetic resonance (NMR) and supported by 2H SP/MAS NMR experiments. The study shows that the arabinan side chains...... hydrate more readily than the galactan side chains and suggests that the overall hydration properties can be controlled by modifying the ratio of these side chains. Enzymatic modification of native (NA) RG-I provided samples with reduced content of arabinan (sample DA), galactan (sample DG), or both side...... chains (sample DB). Results of these samples suggested that hydration properties were determined by the length and character of the side chains. NA and DA exhibited similar hydration characteristics, whereas DG and DB were difficult to hydrate because of the less hydrophilic properties of the rhamnose...

  12. Hydronephrosis alters cardiac ACE2 and Mas receptor expression in mice.

    Science.gov (United States)

    Zhang, Yanling; Ma, Lulu; Wu, Junyan; Chen, Tingting

    2015-06-01

    Hydronephrosis is characterized by substantial loss of tubules and affects renin secretion in the kidney. However, whether alterations of angiotensin-converting enzyme (ACE), ACE2 and Mas receptor in the heart are observed in hydronephrosis is unknown. Thus, we assessed these components in hydronephrotic mice treated with AT1 receptor blockade and ACE inhibitor. Hydronephrosis was induced by left ureteral ligation in Balb/C mice except sham-operated animals. The levels of cardiac ACE, ACE2 and Mas receptor were measured after treatment of losartan or enalapril. Hydronephrosis led to an increase of ACE level and a decrease of ACE2 and Mas receptor in the heart. Losartan decreased cardiac ACE level, but ACE2 and Mas receptor levels significantly increased in hydronephrotic mice (p Hydronephrosis increased cardiac ACE and suppressed ACE2 and Mas receptor levels. AT1 blockade caused sustained activation of cardiac ACE2 and Mas receptor, but ACE inhibitor had the limitation of such activation of Mas receptor in hydronephrotic animals. © The Author(s) 2015.

  13. The Factors of Forming the National HR-Management Model

    Directory of Open Access Journals (Sweden)

    Elena P. Kostenko

    2017-12-01

    Full Text Available There are some factors considered in this article, which influence the forming of national HR-management model. The group-forming criterion is the nature of factors, that determine the system of HR-management as a system of corporate culture values, norms and rules of organizational behavior, ways of realization some important managing functions and dominating approaches to make decisions. This article shows that the plurality of combinations in different factors leads to forming the unique HR-management model. The geoclimatic factor influences the principles of the labor organization (orientation primarily on individual or collective forms of labor, attitude to the management experience of other countries, attitude to resources, etc., the distribution of labor resources, the level of labor mobility, and the psychosocial type of employee. Models of man's labor behavior are constituted In the process of historical development. Attention is focused on the formation of a national HR-model, such as the conducted socio-economic policy, the characteristics of the institutional environment, economic goals and priorities of the country's development, the level of development and the nature of the national productive forces and economic structures. Much attention was paid to the analysis of the historically formed value system and labor traditions, which influence the approaches to HR-management. As far as religion influences the model of person’s inclusion in labor, motives of labor behavior, management culture of a certain employee, preferred payment etc., we examined how the main traditional religions (Christianity, Islam, Judaism, Buddhism, Confucianism, Hinduism influence the HR-management system in different countries.

  14. Classification of Ap-stars HR 830 and ZI CVn

    International Nuclear Information System (INIS)

    Zverko, J.

    1984-01-01

    Two ambiguously classified Ap-stars, HR 830 and 21 CVn, are studied. The observational data are compared with the data for normal stars αDel and αLyr. Star HR 830 is classified as Ap of type Si based on the enhanced absorption in the Si lines and photometric variability in UBV. 21 CVn is classified as Ap Si based on weaker absorption of helium, the variability of helium lines, photometric periodic variability and the properties of the UV spectrum. It is concluded that the photometric periodic variability is a good indicator of Ap-properties of rapidly rotating A and late B stars. (author)

  15. Limited field investigation report for the 100-HR-3 operable unit

    International Nuclear Information System (INIS)

    1994-09-01

    This limited field investigation (LFI) was conducted to assess the applicability of interim remedial measures (IRM) for reducing human health and environmental risks within the 100-HR-3 Groundwater Operable Unit. The 100-HR-3 Operable Unit is comprised of three subareas; the 100 D Area, the 100 H Area and those portions of the 600 Area between the two reactor areas. The operable unit is one of seven operable units associated with the 100 D and H Areas. Operable units 100-DR-1, 100-DR-2, 100-DR-3, 100-HR-1, 100-HR-2 and 100-IU-4 address contaminant sources while 100-HR-3 addresses contamination present in the underlying groundwater. The primary method of field investigation used during this LFI was the installation and sampling of monitoring wells. Samples were collected from the groundwater and soils, and submitted for laboratory analysis. Boreholes were surveyed for radiological contamination using downhole geophysical techniques to further delineate the locations and levels of contaminants. All samples were screened to ascertain the presence of volatile organic compounds and radionuclides. Analytical data were subjected to validation; all round one, two and three and a minimum of 10% of round four data associated with the LFI were validated. A screening method was used to identify contaminants of potential concern (COPC). This screening method eliminated from further consideration, constituents that were below background. Constituents which are considered non-toxic to humans were eliminated from the human health evaluation. Data consistency and blank contamination were also evaluated in the screening process. These COPC were then evaluated further in the qualitative risk assessment (QRA). A human health QRA was performed using conservative (maximum equilibrated contaminant levels from the LFI) analyses

  16. Radioactive waste legislation. Hearings before the Subcommittee on Energy and the Environment of the Committee on Interior and Insular Affairs, House of Representatives, Ninety-Seventh Congress, First Session on H.R. 1993; H.R. 2800; H.R. 2840; H.R. 2881; H.R. 3809, June 23 and 25; July 9, 1981

    International Nuclear Information System (INIS)

    Anon.

    1981-01-01

    This three-day hearing was held to consider five bills on radioactive waste, set priorities for a repository construction program, consider an administration proposal to develop a small-scale test facility for deep permanent storage of high-level wastes, and determine what role the public and private sectors should assume. The hearing record includes the text of H.R. 1993, H.R. 2800, H.R. 2840, H.R. 2881, and H.R. 3809; the statements of 10 witnesses and two panels; and three appendices with additional material submitted for the record

  17. PENGEMBANGAN EKOWISATA BERBASIS KERAKYATAN DI BANJAR NYUH KUNING, DESA MAS, UBUD

    Directory of Open Access Journals (Sweden)

    AGUNG SRI SULISTYAWATI

    2015-06-01

    Full Text Available The objective of this study is (1 to identify the potential of Banjar Nyuh Kuning Mas Village, Ubud has to offer as means of attraction in ecotourism which may be accomplished by identifying physical and non physical potential. (2 to develope a community based strategy in ecotourism. The sampling technique used is purposive sampling and accidental sampling. Data collection is accomplished through observatioan, questionaire, focus group discussion and documentation. Data analysis is by qualitative descriptive and SWOT. The result of this study is that Banjar Nyuh Kuning has the potential to be developed as an ecotourism on the basis of physical and non physical grounds. The perception of the community and tourists are in agreement to the developement of ecotourism activity which incorporate local community, nature oriented activity and has the potential to increase their income, thus resulting in a destination for leisure and recreation. There are a few results of alternative strategies such as; development strategies of ecotourism products, development strategies of human resources, development strategies of management and strategies in upgrading security. To make Banjar Nyuh Kuning as an attraction for ecotourism activity which is based on nature then the strategy for development has to be efficient and limited. Further study has to be taken for the marketing aspect and managing ecotourism object to further the developent in a comprehensive manner.

  18. Molybdenum modified phosphate glasses studied by 31P MAS NMR and Raman spectroscopy.

    Science.gov (United States)

    Szumera, Magdalena

    2015-02-25

    Glasses have been synthesized in the system P2O5-SiO2-K2O-MgO-CaO modified by addition of MoO3. Glasses were prepared by conventional fusion method from 40 g batches. The influence of Mo-cations on the analysed glass structure was investigated by means of Raman and (31)P MAS-NMR techniques. It has been found that molybdate units can form Mo[MoO4/MoO6]-O-P and/or Mo[MoO4/MoO6]-O-Si bonds with non-bridging oxygens atoms of Q2 methaphosphate units, resulting in the transformation of chain methaphosphate structure into pyrophosphate and finally into orthophosphate structure. It has been also found that increasing amount of MoO3 in the structure of investigated glasses causes their gradual depolymerization and molybdenum ions in the analysed glass matrix act as modifying cations. Copyright © 2014 Elsevier B.V. All rights reserved.

  19. Global well-posedness for Schrödinger equation with derivative in H(R)

    Science.gov (United States)

    Miao, Changxing; Wu, Yifei; Xu, Guixiang

    In this paper, we consider the Cauchy problem of the cubic nonlinear Schrödinger equation with derivative in H(R). This equation was known to be the local well-posedness for s⩾1/2 > (Takaoka, 1999 [27]), ill-posedness for s (Biagioni and Linares, 2001 [1], etc.) and global well-posedness for s>1/2 > (I-team, 2002 [10]). In this paper, we show that it is global well-posedness in the endpoint space H(R), which remained open previously. The main approach is the third generation I-method combined with a new resonant decomposition technique. The resonant decomposition is applied to control the singularity coming from the resonant interaction.

  20. Smoke, Clouds and Radiation Brazil NASA ER-2 Moderate Resolution Imaging Spectrometer (MODIS) Airborne Simulator (MAS) Data

    Data.gov (United States)

    National Aeronautics and Space Administration — SCARB_ER2_MAS data are Smoke, Clouds and Radiation Brazil (SCARB) NASA ER2 Moderate Resolution Imaging Spectrometer (MODIS) Airborne Simulator (MAS)...

  1. Can HR practices retain flexworkers with their agency?

    NARCIS (Netherlands)

    Kroon, B.; Freese, C.

    2013-01-01

    Purpose Workers have different motives to be employed at specialist contract work agencies, such as career development aspirations, or a desire for freedom and independence. The purpose of this paper is to study how these different motives relate to the appreciation of HR practices applied by

  2. Research on electron beam welding technology of steel HR-4

    International Nuclear Information System (INIS)

    Guo Peng; Guan Kai

    2001-01-01

    The electron beam weldability of HR- 4 steels (J75 and J90) is studied and the welding parameters needed for design and usage are presented. The assessment on the effect of mechanical properties by different processing order of welding and heat-treatment is made

  3. In-sourcing HR: shared service centres in the Netherlands

    NARCIS (Netherlands)

    Farndale, Elaine; Paauwe, Jaap; Hoeksema, Ludwig

    2009-01-01

    Due to the impact of now widely-available technologies, new logics behind the organisation of the HR function through the in- and outsourcing of HRM activities have been emerging, particularly addressing issues of integration, cost-efficiency and competitive advantage. In particular, increasing

  4. The Perceived Importance of HR duties to Danish line managers

    DEFF Research Database (Denmark)

    Brandl, Julia; Madsen, Mona Toft; Madsen, Henning

    2009-01-01

    Today, HR scholars widely acknowledge that realising HRM requires the involvement of all managers and that the personal motivation of line managers plays an important role in their successful involvement. Yet, previous research has neglected to study how line managers rate the importance of parti...

  5. HR practices for enhancing sustainable employability : implementation, use, and outcomes

    NARCIS (Netherlands)

    Ybema, Jan Fekke; van Vuuren, Tinka; van Dam, Karen

    2017-01-01

    With the aging of the workforce, organizations need to maintain or improve the sustainable employability of their workforce throughout their working life. This raises the question which HR practices increase workers’ sustainable employability at work. The aim of this study is to investigate the

  6. Enrico Chiaveri: The dialogue in the HR Strategy

    CERN Multimedia

    2009-01-01

    Enrico Chiaveri has been Head of the Human Resources Department since 2005. A core part of his department’s mission with the new Management is to develop and implement a strategic HR approach for our forward-looking Organization. He explained key aspects of the HR strategy to the Bulletin. For the first time in CERN’s history, a head of the HR Department and his deputy - Anne-Sylvie Catherin - invited the staff to a general information meeting on 23 February 2009. The scope of the meeting was to present the status of a number of current initiatives that will improve and tailor CERN’s HR strategy to the needs of the Organization and its staff, and also open up dialogue. Presented for the first time in an integrated way, the initiatives include contract policy, MARS, a staff survey, CERN’s values, a performance model, recruitment & outreach, learning & development, internal mobility and the development of a code of condu...

  7. THE CHANGING ROLE OF HR: VALUES AND CONTRIBUTION

    DEFF Research Database (Denmark)

    Andersen, Torben; Krogager, Per

    2011-01-01

    This paper illustrates, through a case-study of one of the old life sciences and diagnostics companies in Denmark, Radiometer Medical Plc. (now part of the Danaher Corporation), how the HR-department starts to work in a much more systematic way with effectiveness and efficiency, in the attempt...... with a stronger emphasis on core values and rationalizing the function itself....

  8. Learning Culture, Line Manager and HR Professional Practice

    Science.gov (United States)

    Harrison, Patricia

    2011-01-01

    Purpose: This paper aims to focus on the role of line management and learning culture in the development of professional practice for the human resource (HR) practitioner. Design/methodology/approach: Three-year longitudinal, matched-pair study involving five participants and their line managers. Findings: Two of the five participants experienced…

  9. Atypical Employment Relationships and Commitment: Wishful Thinking or HR Challenge?

    NARCIS (Netherlands)

    Torka, Nicole

    2004-01-01

    Nowadays, simultaneously maintaining flexible working practices and commitment is an important topic for HR managers since they both can contribute to organisational success. However, many HRM researchers and practitioners are unsure whether these can go together as job security is often seen as a

  10. HR Manager Leadership in Quality Improvement in a College Environment

    Science.gov (United States)

    Sharabi, Moshe

    2010-01-01

    Purpose: The purpose of this paper is to present the influence of the human resource (HR) manager on the quality of service in an academic college, and the human resource management (HRM) outcomes of the process. Design/methodology/approach: The paper relates to a customer satisfaction survey. More than 120 questionnaires were completed by the…

  11. Stimulating teachers’ team performance through team-oriented HR practices

    NARCIS (Netherlands)

    Bouwmans, Machiel; Runhaar, Piety; Wesselink, Renate; Mulder, Martin

    2017-01-01

    Teams of teachers are increasingly held accountable for the quality of education and educational reforms in vocational education and training institutions. However, historically teachers have not been required to engage in deep-level collaboration, thus team-oriented HR practices are being used

  12. Multinuclear MAS NMR studies on coked zeolites H-ZSM-5

    International Nuclear Information System (INIS)

    Ernst, H.; Freude, D.; Hunger, M.; Pfeifer, H.

    1991-01-01

    During the cracking process carbonaceous materials are deposited on the outer or inner surface of the catalyst. These deposits are in many cases the main cause of catalyst deactivation. Magic angle spinning (MAS) NMR investigations and catalytic n-hexane cracking were carried out on H-ZSM-5 zeolites after a mild hydrothermal de-alumination. By 13 C CP MAS NMR it could be shown that the enhanced catalytic activity does not enhance the coke formation and that the chemical nature of these deposits is essentially aromatic. From 1 H MAS NMR studies performed on shallow-bed activated sealed samples and 27 Al and 29 Si MAS NMR on rehydrated samples it follows that for high coke concentrations the catalyst deactivation is caused mainly by blocking of Broensted acid sites. (author). 27 refs.; 3 figs.; 2 tabs

  13. 48 CFR 538.270 - Evaluation of multiple award schedule (MAS) offers.

    Science.gov (United States)

    2010-10-01

    ... SERVICES ADMINISTRATION SPECIAL CATEGORIES OF CONTRACTING FEDERAL SUPPLY SCHEDULE CONTRACTING Establishing and Administering Federal Supply Schedules 538.270 Evaluation of multiple award schedule (MAS) offers... determining the Government's price negotiation objectives, consider the following factors: (1) Aggregate...

  14. MAS Integration and Controllership Effectiveness: Evidence of a Preparer-User Perception Gap

    OpenAIRE

    Weißenberger, Barbara E.; Angelkort, Hendrik; Holthoff, Gero

    2012-01-01

    Recent evidence suggests that managers establish a positive link between management accounting system (MAS) integration and controllership effectiveness, which is fully mediated by the perceived consistency of financial language. Our paper extends this research by analyzing whether controllers have similar perceptions on MAS design. Testing a series of multi-group structural equation models, we find evidence for a preparer-user perception gap with respect to the mediating impact of a consiste...

  15. Genotyping-by-sequencing (GBS), an ultimate marker-assisted selection (MAS) tool to accelerate plant breeding.

    Science.gov (United States)

    He, Jiangfeng; Zhao, Xiaoqing; Laroche, André; Lu, Zhen-Xiang; Liu, HongKui; Li, Ziqin

    2014-01-01

    Marker-assisted selection (MAS) refers to the use of molecular markers to assist phenotypic selections in crop improvement. Several types of molecular markers, such as single nucleotide polymorphism (SNP), have been identified and effectively used in plant breeding. The application of next-generation sequencing (NGS) technologies has led to remarkable advances in whole genome sequencing, which provides ultra-throughput sequences to revolutionize plant genotyping and breeding. To further broaden NGS usages to large crop genomes such as maize and wheat, genotyping-by-sequencing (GBS) has been developed and applied in sequencing multiplexed samples that combine molecular marker discovery and genotyping. GBS is a novel application of NGS protocols for discovering and genotyping SNPs in crop genomes and populations. The GBS approach includes the digestion of genomic DNA with restriction enzymes followed by the ligation of barcode adapter, PCR amplification and sequencing of the amplified DNA pool on a single lane of flow cells. Bioinformatic pipelines are needed to analyze and interpret GBS datasets. As an ultimate MAS tool and a cost-effective technique, GBS has been successfully used in implementing genome-wide association study (GWAS), genomic diversity study, genetic linkage analysis, molecular marker discovery and genomic selection under a large scale of plant breeding programs.

  16. Human Resource Predictive Analytics HRPA For HR Management In Organizations

    Directory of Open Access Journals (Sweden)

    Sujeet N. Mishra

    2015-08-01

    Full Text Available Human resource predictive analytics is an evolving application field of analytics for HRM purposes. The purpose of HRM is measuring employee performance and engagement studying workforce collaboration patterns analyzing employee churn and turnover and modelling employee lifetime value. The motive of applying HRPA is to optimize performances and produce better return on investment for organizations through decision making based on data collection HR metrics and predictive models. The paper is divided into three sections to understand the emergence of HR predictive analytics for HRM. Firstly the paper introduces the concept of HRPA. Secondly the paper discusses three aspects of HRPA a Need b Approach amp Application c Impact. Lastly the paper leads to the conclusion on HRPA.

  17. LBT observations of the HR8799 planetary system

    Science.gov (United States)

    Mesa, D.; Arcidiacono, C.; Claudi, R. U.; Desidera, S.; Esposito, S.; Gratton, R.; Masciadri, E.

    2013-09-01

    We present here observations of the HR8799 planetary system performed in H and Ks band exploiting the AO system at the Large Binocular Telescope and the PISCES camera. Thanks to the excellent performence of the instrument we were able to detect for the first time the inner known planet of the system (HR8799) in the H band. Precise photometric and astrometric measures have been taken for all the four planets. Further, exploiting ours and previous astrometric results, we were able to put some limits on the planetary orbits of the four planets. The analysis of the dinamical stability of the system seems to show lower planetary masses than the ones adopted until now.

  18. The latest on the recent HR staff survey

    CERN Multimedia

    2009-01-01

    The data collected in the framework of the staff survey sent out by the Human Resources (HR) Department in March this year are currently being analysed. The first results concern the response rate and the breakdown of participants. 1328 staff members replied to the questionnaire, representing a response rate of close to 60%. Marie-Luce Falipou, who is in charge of the project within the HR Department, is evidently satisfied with the result: "The high response rate shows that the staff appreciated HR’s efforts to sound out their opinions and felt concerned by the subjects covered in the questionnaire". All the data are now being processed by the team led by Philippe Sarnin, Director of the Social Psychology Department at the University of Lyon2. "The number of responses submitted during the 15 days the form was available on line was very satisfactory. This is a vital factor in ensuring that we are able to build up an accurate pictu...

  19. HR strategy – necessity or fad for business sustainability?

    Directory of Open Access Journals (Sweden)

    Ghinea Valentina Mihaela

    2016-07-01

    Full Text Available The present paper pleads for the awareness of HR strategy importance, in terms of proper design and implementation, as they definitely could impede or sustain the development of an organization. By making use of G.VALI, the model of organizational culture dynamics, we look for revealing the impact that (non-existence of HR strategy, its alignment and coherence could have on the organization success. As proven by human experience, all types of strategies could work and be effective in certain conditions. Even more, no one can say that one strategy is better than other. However, in the same way, there is no guarantee of some strategies success. In this light, the difference lays in the handy and clever interlock of the country specific advantages and firm (-tobe specific advantages. For achieving this specific aim, vertical (alignment and horizontal (coherence integration of each functional strategy must be ensured.

  20. Teaching HR Professionals: The Classroom as a Community of Practice

    Directory of Open Access Journals (Sweden)

    Alex Avramenko

    2013-05-01

    Full Text Available This paper introduces an innovative course design incorporating both communities of practice and reflective practice as a learning strategy for part-time learners in higher education. The new design has been applied to teaching HR practitioners in a UK-based business school. Findings indicate that the suggested way of organizing teaching and learning for part-time professionals is very informative and facilitates a richer engagement with theory whilst addressing issues of practice.

  1. Acute hyperhydration reduces athlete biological passport OFF-hr score

    DEFF Research Database (Denmark)

    Bejder Rasmussen, Jacob; Hoffmann, M F; Ashenden, M

    2016-01-01

    Anecdotal evidence suggests that athletes hyperhydrate to mask prohibited substances in urine and potentially counteract suspicious fluctuations in blood parameters in the athlete biological passport (ABP). It is examined if acute hyperhydration changes parameters included in the ABP. Twenty...... ingestion, and 54% (n = 19), 45%, and 47% (n = 19) were identified 40, 60, and 80 min, respectively, after ingestion. In conclusion, acute hyperhydration reduces ABP OFF-hr and reduces ABP sensitivity....

  2. Photoelectric photometry of the Am star HR = V423 Per

    International Nuclear Information System (INIS)

    Jerzykiewicz, M.

    1989-01-01

    This spectroscopic binary is the largest amplitude variable among Am stars. UBV observations of the star are presented. They show that in 1964 and 1965 it was constant in B and was only marginally variable in U. The hypothesis of the ellipsoidal variability of HR 976 is then discussed and found untenable. It is pointed out that this result may reopen the issue of light variability of Am stars. 10 refs., 2 figs., 2 tabs. (author)

  3. CROATIAN ADULT SPOKEN LANGUAGE CORPUS (HrAL

    Directory of Open Access Journals (Sweden)

    Jelena Kuvač Kraljević

    2016-01-01

    Full Text Available Interest in spoken-language corpora has increased over the past two decades leading to the development of new corpora and the discovery of new facets of spoken language. These types of corpora represent the most comprehensive data source about the language of ordinary speakers. Such corpora are based on spontaneous, unscripted speech defined by a variety of styles, registers and dialects. The aim of this paper is to present the Croatian Adult Spoken Language Corpus (HrAL, its structure and its possible applications in different linguistic subfields. HrAL was built by sampling spontaneous conversations among 617 speakers from all Croatian counties, and it comprises more than 250,000 tokens and more than 100,000 types. Data were collected during three time slots: from 2010 to 2012, from 2014 to 2015 and during 2016. HrAL is today available within TalkBank, a large database of spoken-language corpora covering different languages (https://talkbank.org, in the Conversational Analyses corpora within the subsection titled Conversational Banks. Data were transcribed, coded and segmented using the transcription format Codes for Human Analysis of Transcripts (CHAT and the Computerised Language Analysis (CLAN suite of programmes within the TalkBank toolkit. Speech streams were segmented into communication units (C-units based on syntactic criteria. Most transcripts were linked to their source audios. The TalkBank is public free, i.e. all data stored in it can be shared by the wider community in accordance with the basic rules of the TalkBank. HrAL provides information about spoken grammar and lexicon, discourse skills, error production and productivity in general. It may be useful for sociolinguistic research and studies of synchronic language changes in Croatian.

  4. High-performance HR practices, positive affect and employee outcomes

    OpenAIRE

    Mostafa, Ahmed

    2017-01-01

    Purpose – The purpose of this paper is to provide insight into the affective or emotional mechanisms that underlie the relationship between high-performance HR practices (HPHRP) and employee attitudes and behaviours. Drawing on affective events theory (AET), this paper examines a mediation model in which HPHRP influence positive affect which in turn affects job satisfaction and organizational citizenship behaviours (OCBs). Design/methodology/approach – Two-wave data was collected from a sampl...

  5. THE IMPACT OF HR MANAGERS’ ROLES ON IMPLEMENTING BEST HR PRACTICES AND ATTRACTING AND RETAINING BEST EMPLOYEES

    OpenAIRE

    Nicoleta Valentina FLOREA

    2014-01-01

    Today’s organizations are facing new challenges, which require them to make effective decisions in order to solve complex issues. These decisions are generally made at higher levels in the organization’s hierarchical structure, where managers maintain power and control to influence organizational goals, including the behaviors and the attitudes of their subordinates. In this article we will show the importance of having effective managers, especially in HR, who can positively influence attrac...

  6. Neuroprotective Mechanisms of the ACE2-Angiotensin-(1-7)-Mas Axis in Stroke

    DEFF Research Database (Denmark)

    Bennion, Douglas M; Haltigan, Emily; Regenhardt, Robert W

    2015-01-01

    The discovery of beneficial neuroprotective effects of the angiotensin converting enzyme 2-angiotensin-(1-7)-Mas axis [ACE2-Ang-(1-7)-Mas] in ischemic and hemorrhagic stroke has spurred interest in a more complete characterization of its mechanisms of action. Here, we summarize findings that desc......The discovery of beneficial neuroprotective effects of the angiotensin converting enzyme 2-angiotensin-(1-7)-Mas axis [ACE2-Ang-(1-7)-Mas] in ischemic and hemorrhagic stroke has spurred interest in a more complete characterization of its mechanisms of action. Here, we summarize findings...... that describe the protective role of the ACE2-Ang-(1-7)-Mas axis in stroke, along with a focused discussion on the potential mechanisms of neuroprotective effects of Ang-(1-7) in stroke. The latter incorporates evidence describing the actions of Ang-(1-7) to counter the deleterious effects of angiotensin II...... complete understanding of the mechanisms of action of Ang-(1-7) to elicit neuroprotection will serve as an essential step toward research into potential targeted therapeutics in the clinical setting....

  7. A software framework for analysing solid-state MAS NMR data

    International Nuclear Information System (INIS)

    Stevens, Tim J.; Fogh, Rasmus H.; Boucher, Wayne; Higman, Victoria A.; Eisenmenger, Frank; Bardiaux, Benjamin; Rossum, Barth-Jan van; Oschkinat, Hartmut; Laue, Ernest D.

    2011-01-01

    Solid-state magic-angle-spinning (MAS) NMR of proteins has undergone many rapid methodological developments in recent years, enabling detailed studies of protein structure, function and dynamics. Software development, however, has not kept pace with these advances and data analysis is mostly performed using tools developed for solution NMR which do not directly address solid-state specific issues. Here we present additions to the CcpNmr Analysis software package which enable easier identification of spinning side bands, straightforward analysis of double quantum spectra, automatic consideration of non-uniform labelling schemes, as well as extension of other existing features to the needs of solid-state MAS data. To underpin this, we have updated and extended the CCPN data model and experiment descriptions to include transfer types and nomenclature appropriate for solid-state NMR experiments, as well as a set of experiment prototypes covering the experiments commonly employed by solid-sate MAS protein NMR spectroscopists. This work not only improves solid-state MAS NMR data analysis but provides a platform for anyone who uses the CCPN data model for programming, data transfer, or data archival involving solid-state MAS NMR data.

  8. THE IMPACT OF HR MANAGERS’ ROLES ON IMPLEMENTING BEST HR PRACTICES AND ATTRACTING AND RETAINING BEST EMPLOYEES

    Directory of Open Access Journals (Sweden)

    Nicoleta Valentina FLOREA

    2014-10-01

    Full Text Available Today’s organizations are facing new challenges, which require them to make effective decisions in order to solve complex issues. These decisions are generally made at higher levels in the organization’s hierarchical structure, where managers maintain power and control to influence organizational goals, including the behaviors and the attitudes of their subordinates. In this article we will show the importance of having effective managers, especially in HR, who can positively influence attracting intellectual capital and acquire knowledge management, by increasing employees motivation, job satisfaction, performance, and organizational commitment, in order to achieve high levels of productivity and efficiency. Also, we will evaluate the HR managers’ roles in order to obtain performance by managing, controlling, evaluating, analyzing, auditing, forecasting, and integrating effectively knowledge management and intellectual capital in organizations. Our study is made in large organizations from Dambovita County, Romania, and it demonstrates that employees need excellent HR managers to obtain the best from them and to face a changing environment.

  9. NEW PRECISION ORBITS OF BRIGHT DOUBLE-LINED SPECTROSCOPIC BINARIES. IV. 66 ANDROMEDAE, HR 6979, AND HR 9059

    International Nuclear Information System (INIS)

    Fekel, Francis C.; Williamson, Michael H.; Tomkin, Jocelyn

    2010-01-01

    We have determined improved spectroscopic orbits for three double-lined binaries, 66 And (F4 V), HR 6979 (Am), and HR 9059 (F5 IV) using radial velocities from the 2.1 m telescope at McDonald Observatory, the coude feed telescope at Kitt Peak National Observatory, and 2 m telescope at Fairborn Observatory. The orbital periods range from 11.0 to 14.3 days, and all three systems have eccentric orbits. The new orbital dimensions (a 1 sin i and a 2 sin i) and minimum masses (m 1 sin 3 i and m 2 sin 3 i) have accuracies of 0.2% or better. All six components of the three binary systems are rotating more slowly than their predicted pseudosynchronous rotational velocities. Hipparcos photometry of HR 9059 shows that this system has partial eclipses. Its components are nearly identical in mass and are at the very end of their main-sequence lifetimes or perhaps have just begun to traverse the Hertsprung gap.

  10. Why a well-designed HR shared service provider fails to create end-user value?

    NARCIS (Netherlands)

    Meijerink, Jeroen Gerard; Bondarouk, Tatiana; Looise, Jan C.

    2011-01-01

    Human resource shared services centres (HR SSCs) are foreseen as improving HR service delivery for their end-users: employees, line managers and decentralized HR professionals. Although the concept expects the benefits of HR SSCs to come from centralizing knowledge and decentralizing the control

  11. Escala de atitudes frente ao dinheiro (MAS: Teste de modelos e poder preditivo

    Directory of Open Access Journals (Sweden)

    Carlos Eduardo Pimentel

    2012-01-01

    Full Text Available The social importance attached to money and its role as an important motivator of behavior justifies the study of its psychosocial aspects. But there is a lack of studies concerning attitudinal or psychological aspects of money in Brazil. In order to encourage research in this context, the validity of the Money Attitudes Scale (MAS was tested using confirmatory factor approaches. Results supported a brief 16-items version of the scale and replicated the factor analytic pattern with satisfactory internal consistency for the factors of power, retention, distrust, and anxiety. Age differences were observed regarding money attitudes of power, and the predictive role of the MAS to account for consumer behavior was also confirmed. This version of the MAS shows evidences of factorial validity and reliability, justifying its use in future research.

  12. 100-HR-2 Operable Unit Focused Feasibility study report

    International Nuclear Information System (INIS)

    1995-01-01

    The standard Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA) Feasibility Study (FS) includes development and screening of alternatives (Phases 1 and 2) and the detailed analysis of alternatives (Phase 3). This focused feasibility study (FFS) was conducted for the 100-HR-2 Operable Unit (OU) at the Hanford Site in southeastern Washington. This FFS constitutes the Phase 3 portion of the FS process for the remedial alternatives initially developed and screened in the 100 Area Feasibility Study Phases 1 and 2 (DOE-RL 1993a). The objective of this OU-specific FFS is to provide decision makers with sufficient information to allow appropriate and timely selection of interim remedial measures (IRM) for the seven IRM candidate sites associated with the 100-HR-2 OU. The IRM candidate waste sites identified in Table ES-1 are determined in the limited field investigation (DOE-RL 1994b). Site profiles are developed for each of these waste sites. The site profiles are used in the application of the plug-in approach. The waste site either plugs into the analysis of the alternatives for the group, or deviations from the developed group alternatives are described and documented. A summary for the 100-HR-2 IRM candidate waste site is as follows: none of the waste sites require additional alternative development. six of the seven waste sites directly plug into the waste site group alternatives. The site-specific detailed analysis is conducted, referencing the waste site group analysis as appropriate. A waste site detailed analysis summary is presented in Table ES-1.A comparative analysis of remedial alternatives is presented for each waste site. A summary of the comparative analysis is presented in Table ES-2

  13. HR diagrams derived from the Michigan Spectral Catalogue

    International Nuclear Information System (INIS)

    Houk, N.; Fesen, R.

    1978-01-01

    The authors present some HR diagrams constructed using data from the Michigan Spectral Catalogues. Houk (1975) has been systematically reclassifying the Henry Draper stars on the MK system, from the south pole northward. Objective-prism plates, with a reciprocal dispersion of 108 A/mm, have been taken with the Michigan Curtis Schmidt telescope at Cerro Tololo Inter-American Observatory in Chile. The spectra are classified visually from the plates, and the results are put onto IBM cards and magnetic tape from which the catalogues are produced. (Auth.)

  14. 10 MMBt/Hr AFBC Commercial Demonstration Cedar Lane Farms

    Energy Technology Data Exchange (ETDEWEB)

    Harold M. Keener; Mary H. Wicks; Tom Machamer; Dave Hoecke; Don Bonk; Bob Brown

    2005-10-31

    The objective of this project was to demonstrate and promote the commercialization of coal-fired atmospheric fluidized bed combustion (AFBC) systems, with limestone addition for SO2 emissions control and a baghouse for particulate emissions control. This AFBC system was targeted for small scale industrial-commercial-institutional space and process heat applications in the 4-40 MMBtu/hr size range. A cost effective and environmentally acceptable AFBC technology in this size range could displace a considerable amount of heating gas and oil with coal, while resulting in significant total cost savings to the owner/operators.

  15. Development of a generic, computerized nuclear material accountability system: NucMAS

    International Nuclear Information System (INIS)

    Cornell, M.D.; O'Leary, J.M.

    1987-01-01

    The application NucMAS provides basic computerized accountability functions for the Savannah River Plant (SRP) Separations Department Material Balance Areas (MBA's). These functions include data entry, data management, calculations, and report generation. NucMAS can be used both for routine reporting to the SRP central Material Control and Accounting (MC and A) system and for rapid ad hoc queries in emergency situations. The system is designed to work with any process handling one or more of the 17 accountable nuclear materials specified by the Department of Energy (DOE). It relies on user-supplied configuration data to drive data prompts, report headings, data validations, and calculations

  16. Who bears the burden of international taxation? Evidence from cross-border M&As

    NARCIS (Netherlands)

    Huizinga, H.P.; Voget, J.; Wagner, W.B.

    2012-01-01

    Cross-border M&As can trigger additional taxation of the target's income in the form of non-resident dividend withholding taxes and acquirer-country corporate income taxation. This paper finds that this additional international taxation is fully capitalized into lower takeover premiums. In contrast,

  17. Acceptance Test Report for the Modular Automation System (MAS) Manufactured by Honeywell Inc

    International Nuclear Information System (INIS)

    ANDERSON, D.L.

    2000-01-01

    This document details the performance of the acceptance test of the Honeywell MAS Control System for equipment to be installed in gloveboxes HA-20MB and HA-211 at a later date. Equipment that was anticipated included 6 stabilization furnaces, only three and their associated equipment were installed

  18. SecMAS: Security Enhanced Monitoring and Analysis Systems for Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Ding Chao

    2016-01-01

    Full Text Available The monitoring, control, and security guarantee for the communication in the wireless sensor networks (WSNs are currently treated as three independent issues and addressed separately through specialized tools. However, most cases of WSNs applications requires the network administrator change the network configuration in a very short time to response to the change of observed phenomenon with security guarantee. To meet this requirement, we propose a security enhanced monitoring and control platform named SecMAS for WSNs, which provides the real-time visualization about network states and online reconfiguration of the network properties and behaviours in a resource-efficient way. Besides, basic cryptographic primitives and part of the anomaly detection functionalities are implemented in SecMAS to enabling the secure communication in WSNs. Furthermore, we conduct experiments to evaluate the performance of SecMAS in terms of the latency, throughput, communication overhead, and the security capacity. The experimental results demonstrate that the SecMAS system achieves stable, efficient and secure data collection with lightweight quick-response network control.

  19. Improved background suppression in 1H MAS NMR using composite pulses

    Science.gov (United States)

    Odedra, Smita; Wimperis, Stephen

    2012-08-01

    A well known feature of 1H MAS NMR spectroscopy, particularly of solids where the concentration of 1H nuclei is low, is the presence in the spectrum of a significant broad "background" signal arising from 1H nuclei that are outside the MAS rotor and radiofrequency coil, probably located on the surfaces of the static components of the probehead. A popular method of suppressing this unwanted signal is the "depth pulse" method, consisting of a 90° pulse followed by one or two 180° pulses that are phase cycled according to the "Exorcycle" scheme, which removes signal associated with imperfect 180° pulses. Consequently, only spins in the centre of the radiofrequency coil contribute to the 1H MAS spectrum, while those experiencing a low B1 field outside the coil are suppressed. Although very effective at removing background signal from the spectrum, one drawback with this approach is that significant loss of the desired signal from the sample also occurs. Here we investigate the 1H background suppression problem and, in particular, the use of novel antisymmetric passband composite pulses to replace the simple pulses in a depth pulse experiment. We show that it is possible to improve the intensity of the 1H signals of interest while still maintaining effective background suppression. We expect that these results will be relevant to 1H MAS NMR studies of, for example, nominally perdeuterated biological samples or nominally anhydrous inorganic materials.

  20. Improved background suppression in ¹H MAS NMR using composite pulses.

    Science.gov (United States)

    Odedra, Smita; Wimperis, Stephen

    2012-08-01

    A well known feature of ¹H MAS NMR spectroscopy, particularly of solids where the concentration of ¹H nuclei is low, is the presence in the spectrum of a significant broad "background" signal arising from ¹H nuclei that are outside the MAS rotor and radiofrequency coil, probably located on the surfaces of the static components of the probehead. A popular method of suppressing this unwanted signal is the "depth pulse" method, consisting of a 90° pulse followed by one or two 180° pulses that are phase cycled according to the "Exorcycle" scheme, which removes signal associated with imperfect 180° pulses. Consequently, only spins in the centre of the radiofrequency coil contribute to the ¹H MAS spectrum, while those experiencing a low B₁ field outside the coil are suppressed. Although very effective at removing background signal from the spectrum, one drawback with this approach is that significant loss of the desired signal from the sample also occurs. Here we investigate the ¹H background suppression problem and, in particular, the use of novel antisymmetric passband composite pulses to replace the simple pulses in a depth pulse experiment. We show that it is possible to improve the intensity of the ¹H signals of interest while still maintaining effective background suppression. We expect that these results will be relevant to ¹H MAS NMR studies of, for example, nominally perdeuterated biological samples or nominally anhydrous inorganic materials. Copyright © 2012 Elsevier Inc. All rights reserved.

  1. Characterization and significance of ACE2 and Mas receptor in human colon adenocarcinoma.

    Science.gov (United States)

    Bernardi, Stella; Zennaro, Cristina; Palmisano, Silvia; Velkoska, Elena; Sabato, Nicoletta; Toffoli, Barbara; Giacomel, Greta; Buri, Luigi; Zanconati, Fabrizio; Bellini, Giuseppe; Burrell, Louise M; De Manzini, Nicolò; Fabris, Bruno

    2012-03-01

    A new arm of the renin-angiotensin system (RAS) has been recently characterized; this includes angiotensin converting enzyme (ACE)2 and angiotensin (Ang)1-7, a heptapeptide acting through the Mas receptor (MasR). Recent studies show that Ang1-7 has an antiproliferative action on lung adenocarcinoma cells. The aim of this study was to characterize RAS expression in human colon adenocarcinoma and to investigate whether Ang1-7 exerts an antiproliferative effect on human colon adenocarcinoma cells. Gene, protein expression and enzymatic activity of the main components of the RAS were determined on non-neoplastic colon mucosa as well as on the tumor mass and the mucosa taken 5 cm distant from it, both collected from patients with colon adenocarcinoma. Two different human colon cancer cell lines were treated with AngII and Ang1-7. The novel finding of this study was that MasR was significantly upregulated in colon adenocarcinoma compared with non-neoplastic colon mucosa, which showed little or no expression of it. ACE gene expression and enzymatic activity were also increased in the tumors. However, AngII and Ang1-7 did not have any pro-/antiproliferative effects in the cell lines studied. The data suggest that upregulation of the MasR could be used as a diagnostic marker of colon adenocarcinoma.

  2. 77 FR 43084 - Multiple Award Schedule (MAS) Program Continuous Open Season-Operational Change

    Science.gov (United States)

    2012-07-23

    ... (GSA), Federal Acquisition Service (FAS) intends to institute a Demand Based Model (DBM) designed to... will restore and maintain the MAS program's value to Federal agencies as a streamlined acquisition... adding innovative solutions, improving pricing and simplifying the buying experience. DATES: This change...

  3. 29Si MAS NMR for the zeolite Y - gallium oxide system

    International Nuclear Information System (INIS)

    Sulikowski, B.; Derewinski, M.; Olejniczak, Z.; Segnowski, S.

    1994-01-01

    Wide-pore zeolites modified by gallium oxide has been prepared for catalytic use. Its physico-chemical and catalytic properties have been studied. The structure changes of the catalyst have been investigated by means of MAS NMR spectroscopy. Spectra of 29 Si has been described and discussed

  4. An Analysis of the Rise and Fall of the AA-MAS Policy

    Science.gov (United States)

    Lazarus, Sheryl S.; Thurlow, Martha L.; Ysseldyke, James E.; Edwards, Lynn M.

    2015-01-01

    In 2005, to address concerns about students who might fall in the "gap" between the regular assessment and the alternate assessment based on alternate achievement standards (AA-AAS), the U.S. Department of Education announced that states could develop alternate assessments based on modified achievement standards (AA-MAS). This article…

  5. Considerations for Consortia as States Transition Away from AA-MAS. NCEO Brief. Number 7

    Science.gov (United States)

    National Center on Educational Outcomes, 2014

    2014-01-01

    States with an alternate assessment based on modified achievement standards (AA-MAS) that received a flexibility waiver from some of the requirements of No Child Left Behind are required to phase out their use of this assessment. And, on August 23, 2013, the U.S. Department of Education published a proposed rollback of regulation that allowed the…

  6. Successfully Transitioning from the AA-MAS to the General Assessment. NCEO Policy Directions. Number 22

    Science.gov (United States)

    Lazarus, Sheryl; Thurlow, Martha; Christensen, Laurene; Shyyan, Vitaliy

    2014-01-01

    Federal policy initiatives such as the flexibility waivers for accountability are requiring that states transition away from the use of an alternate assessment based on modified achievement standards (AA-MAS). It is expected that those students who had participated in that assessment will instead participate in the state's general assessment (or a…

  7. Marker-assisted-selection (MAS): A fast track to increase genetic ...

    African Journals Online (AJOL)

    Mapping and tagging of agriculturally important genes have been greatly facilitated by an array of molecular markers in crop plants. Marker-assisted selection (MAS) is gaining considerable importance as it would improve the efficiency of plant breeding through precise transfer of genomic regions of interest (foreground ...

  8. Uranium determination in sea water using the isotopic dilution technique and HR-ICPMS

    International Nuclear Information System (INIS)

    Pereira, Marcio Henrique da Costa; Sarkis, Jorge Eduardo de Souza; Hortellani, Marcos Antonio; Nascimento, Marcos R.L.

    2009-01-01

    In this work, the uranium total and the isotopic composition in seawater were calculated using the isotopic dilution applied to the mass spectrometry. The used tracer was a 233 U solution . Near 99 % of the present salts in the matrix were separated by evaporation up to the saturation point. The uranium present in aqueous phase was separated from the matrix through the ion exchange chromatography using the strong Dowex 1 x 8 200-400 mesh anionic resin in chloridric medium 12 M. The analyses were performed in a high resolution mass spectrometer with plasma inductively coupled source. The method validation was done using the seawater standard CASS-4 (Near shore Seawater Reference Material for Trace metals) produced by the NRC C. The procedure allowed to obtain the fractions exempt of salts, having as consequence a greater stability in the analytical signal, and a rise in the instrumental revenue for a great number of samples. The uranium found in the samples was present in levels considered naturals and were obtained with a precision near 2 %

  9. HUBUNGAN ANTARA PERTUMBUHAN DENGAN KEBERADAAN GEN TAHAN PENYAKIT MAJOR HISTOCOMPATIBILITY COMPLEX (MHC PADA IKAN MAS (Cyprinus carpio

    Directory of Open Access Journals (Sweden)

    Erma Primanita Hayuningtyas

    2016-04-01

    Full Text Available Wabah penyakit koi herpes virus (KHV di Indonesia yang terjadi sejak tahun 2002 merupakan salah satu faktor yang memicu kemerosotan produksi ikan mas budidaya. Pembentukan strain unggul ikan mas tahan KHV dapat menjadi solusi bagi permasalahan tersebut. Pemilihan genotip ikan mas tahan KHV dengan marka molekuler gen major histocompatibility complex class II (MHC-II, khususnya pada alel Cyca DAB 1*05 akan membantu dalam kegiatan seleksi. Penelitian ini bertujuan untuk mengetahui keberadaan gen MHC-II pada populasi dasar G0 ikan mas strain Rajadanu dan hubungannya dengan pertumbuhan (bobot. Metode deteksi keberadaan gen MHC-II pada dua kelompok ikan dengan ukuran berbeda dilakukan dengan teknik PCR. Hubungan antara pertumbuhan ikan mas dengan persentase kemunculan gen MHC-II dianalisis dengan menggunakan program SPSS (Statistical Package for the Social Sciences, sehingga diperoleh korelasi di antara keduanya. Hasil penelitian menunjukkan bahwa hubungan antara pertumbuhan dengan persentase keberadaan gen MHC-II berkorelasi negatif dengan nilai R = -0,742. Hal ini mengindikasikan bahwa semakin cepat pertumbuhan populasi ikan mas maka semakin sedikit persentase individu yang mempunyai gen MHC-II pada setiap populasi ikan mas. Sehingga populasi ikan mas yang pertumbuhannya lambat memiliki tingkat persentase positif MHC-II lebih tinggi (85,71%-100% dibandingkan populasi ikan mas yang pertumbuhannya cepat (42,86%-85,71%.

  10. Team and teamwork in modern european HR management

    Directory of Open Access Journals (Sweden)

    Usheva Mariana

    2016-06-01

    Full Text Available One of the major issues occurring in every contemporary organization is the issue of the efficiency of work and obtaining maximum results from work done. Most often when the issue of increasing the efficiency of work is laid the question of teams and teamwork in various projectя of the company comes to the foreground and frequently no proper differentiation is made between a “group of people” and a “team” and this brings to a large number of misunderstandings of managers and employees with regard to the designation and benefits of team organization of work. There are clear traceable differences between the perception of the concept of “team” and the implementation of teamwork by European and Bulgarian companies and it is good to make the differentiation between them with a view to the HR management.

  11. Multiple Stars Across the H-R Diagram

    CERN Document Server

    Hubrig, Swetlana; Tokovinin, Andrei; Proceedings of the ESO Workshop held in Garching, Germany, 12-15 July 2005

    2008-01-01

    Stars show a marked tendency to be in systems of different multiplicity, ranging from simple binaries and triples to globular clusters with several 10,000's of stars. The formation and evolution of multiple systems remains a challenging part of astrophysics, and the contributions in this book report on the significant progress that had been made in this research field in the last years. The reader will find a variety of research topics addressed, such as the dynamical evolution in multiple stars, the effects of the environment on multiple system parameters, stellar evolution within multiple stars, multiplicity of massive stars, pre-main sequence and intermediate mass stars, multiplicity of low-mass stars from embedded protostars to open clusters, and brown dwarfs and extrasolar planets in multiples. This book presents the proceedings of the ESO Workshop on Multiple Stars across the H-R Diagram held in the summer of 2005.

  12. RADIO ASTROMETRY OF THE CLOSE ACTIVE BINARY HR 5110

    Energy Technology Data Exchange (ETDEWEB)

    Abbuhl, E.; Mutel, R. L.; Lynch, C. [Department of Physics and Astronomy, University of Iowa, Van Allen Hall, Iowa City, Iowa 52242 (United States); Güedel, M. [Department of Astronomy, University of Vienna, Vienna (Austria)

    2015-09-20

    The close active binary HR 5110 was observed at six epochs over 26 days using a global very long baseline interferometry array at 15.4 GHz. We used phase referencing to determine the position of the radio centroid at each epoch with an uncertainty significantly smaller than the component separation. After correcting for proper motion and parallax, we find that the centroid locations of all six epochs have barycenter separations consistent with an emission source located on the KIV secondary, and not in an interaction region between the stars or on the F primary. We used a homogeneous power-law gyrosynchrotron emission model to reproduce the observed flux densities and fractional circular polarization. The resulting ranges of mean magnetic field strength and relativistic electron densities are of the order of 10 G and 10{sup 5} cm{sup −3}, respectively, in the source region.

  13. STAR-BASED METHODS FOR PLEIADES HR COMMISSIONING

    Directory of Open Access Journals (Sweden)

    S. Fourest

    2012-07-01

    Full Text Available PLEIADES is the highest resolution civilian earth observing system ever developed in Europe. This imagery program is conducted by the French National Space Agency, CNES. It has been operating since 2012 a first satellite PLEIADES-HR launched on 2011 December 17th, a second one should be launched by the end of the year. Each satellite is designed to provide optical 70 cm resolution colored images to civilian and defense users. Thanks to the extreme agility of the satellite, new calibration methods have been tested, based on the observation of celestial bodies, and stars in particular. It has then been made possible to perform MTF measurement, re-focusing, geometrical bias and focal plane assessment, absolute calibration, ghost images localization, micro-vibrations measurement, etc… Starting from an overview of the star acquisition process, this paper will discuss the methods and present the results obtained during the first four months of the commissioning phase.

  14. 1H and 23Na MAS NMR spectroscopy of cationic species in CO2 selective alkaline earth metal porous silicoaluminophosphates prepared via liquid and solid state ion exchange

    International Nuclear Information System (INIS)

    Arévalo-Hidalgo, Ana G.; Dugar, Sneha; Fu, Riqiang; Hernández-Maldonado, Arturo J.

    2012-01-01

    The location of extraframework cations in Sr 2+ and Ba 2+ ion-exchanged SAPO-34 was estimated by means of 1 H and 23 Na MAS NMR spectroscopy and spectral deconvolution. Incorporation of the alkaline earth metal cations onto the SAPO framework was achieved via liquid state ion exchange, coupled partial detemplation/solid-state ion exchange, and combination of both techniques. MAS NMR revealed that the level of ion exchange was limited by the presence of protons and sodium cations near hexagonal prisms (site SI), which are relatively difficult to exchange with the alkaline earth metal due to steric and charge repulsion criteria. In addition, the presence of ammonium cations in the supercages facilitated the exchange of otherwise tenacious hydrogen as corroborated by unit cell compositional data as well as enhanced CO 2 adsorption at low partial pressures. The extraframework ammonium species were produced from partial detemplation of the structure-directing agent employed for the SAPO-34 synthesis, tetraethylammonium. - Graphical abstract: MAS NMR was used to elucidate the position the cationic species in alkaline earth metal exchanged silicoaluminophosphates. These species played a significant role during the ion exchange process and, therefore, the materials ultimate CO 2 adsorption performance. Highlights: ► Location of extraframework Sr 2+ or Ba 2+ cations was estimated by means of 1 H and 23 Na MAS NMR. ► Level of Sr 2+ or Ba 2+ ion exchange was limited by the presence of protons and sodium cations. ► Presence of ammonium cations in the supercages facilitated the exchange. ► Sr 2+ and Ba 2+ ion exchanged SAPOs are outstanding CO 2 adsorbents.

  15. Bringing human resources to the table: utilization of an HR balanced scorecard at Mayo Clinic.

    Science.gov (United States)

    Fottler, Myron D; Erickson, Eric; Rivers, Patrick A

    2006-01-01

    Rather than viewing HR as a critical driver of organizational strategy and outcomes, most health care organizations see HR as a drain on the organization's bottom line. Only by aligning HR with the organizational strategy will HR leaders truly get a seat at the leadership table. HR professionals can overcome impediments and gain a seat at the table by learning the language of business and the ways in which organizational leaders use data to drive their decisions. This article shows how Mayo Clinic uses the popular Balanced Scorecard approach to align its measures of HR performance to the organization's strategic plan.

  16. PENGARUH IKLAN DAN ATRIBUT PRODUK TERHADAP KEPUTUSAN PEMBELIAN SMARTPHONE SAMSUNG SERI GALAXY (SURVEI PADA PELANGGAN ITC ROXY MAS

    Directory of Open Access Journals (Sweden)

    Basrah Saidani

    2013-04-01

    Full Text Available Generally, the purpose of this research are: 1 to get more knowledge about Advertising, product attributes and the decision to purchase smartphone Samsung Galaxy series,. 2 to get more knowledge about the influence of Advertising to purchasing decisions smartphone Samsung Galaxy series, 3 to get more knowledge about the influence of product attributes to purchasing decisions smartphone Samsung Galaxy series, 4 to get more knowledge about influence of Advertising and product attributes simultaneously the decision to purchase smartphone Samsung Galaxy series. The observation unit in this research is 100 respondents visitors ITC Roxy Mas – Jakarta to purchase smartphone Samsung Galaxy series. Technique of determining the sample using a convenience sampling technique. Data collection techniques using the questionnaire Liker scale from 1 to 5. Descriptive analysis results showed: 1 the Advertising from Samsung Galaxy series is good enough as a whole but still lacking in message Acceptance and message retention. 2 Attribute a good product overall dimesi dominated by product futures, 3 the decision to purchase is dominated by post-purchase where consumers get satisfaction after buying the Samsung Galaxy series. Hypothesis testing results showed: 1 Advertising have a significant effect on purchasing decisions, 2 product attributes have a significant effect on purchasing decisions, 3 Advertising and product attributes a significant effect on purchasing decisions.

  17. Quantitative in vivo HR-pQCT imaging of 3D wrist and metacarpophalangeal joint space width in rheumatoid arthritis.

    Science.gov (United States)

    Burghardt, Andrew J; Lee, Chan Hee; Kuo, Daniel; Majumdar, Sharmila; Imboden, John B; Link, Thomas M; Li, Xiaojuan

    2013-12-01

    In this technique development study, high-resolution peripheral quantitative computed tomography (HR-pQCT) was applied to non-invasively image and quantify 3D joint space morphology of the wrist and metacarpophalangeal (MCP) joints of patients with rheumatoid arthritis (RA). HR-pQCT imaging (82 μm voxel-size) of the dominant hand was performed in patients with diagnosed rheumatoid arthritis (RA, N = 16, age: 52.6 ± 12.8) and healthy controls (CTRL, N = 7, age: 50.1 ± 15.0). An automated computer algorithm was developed to segment wrist and MCP joint spaces. The 3D distance transformation method was applied to spatially map joint space width, and summarized by the mean joint space width (JSW), minimal and maximal JSW (JSW.MIN, JSW.MAX), asymmetry (JSW.AS), and distribution (JSW.SD)-a measure of joint space heterogeneity. In vivo precision was determined for each measure by calculating the smallest detectable difference (SDD) and root mean square coefficient of variation (RMSCV%) of repeat scans. Qualitatively, HR-pQCT images and pseudo-color JSW maps showed global joint space narrowing, as well as regional and focal abnormalities in RA patients. In patients with radiographic JSN at an MCP, JSW.SD was two-fold greater vs. CTRL (p 3D joint space morphology from HR-pQCT, could improve early detection of joint damage in rheumatological diseases.

  18. Participation and Performance Reporting for the Alternate Assessment Based on Modified Achievement Standards (AA-MAS). Technical Report 58

    Science.gov (United States)

    Albus, Deb; Thurlow, Martha L.; Lazarus, Sheryl S.

    2011-01-01

    This report examines publicly reported participation and performance data for the alternate assessment based on modified achievement standards (AA-MAS). The authors' analysis of these data included all states publicly reporting AA-MAS data, regardless of whether they had received approval to use the results for Title I accountability calculations.…

  19. Angiotensin II Type 2 Receptor and Receptor Mas Are Colocalized and Functionally Interdependent in Obese Zucker Rat Kidney

    DEFF Research Database (Denmark)

    Patel, Sanket N; Ali, Quaisar; Samuel, Preethi

    2017-01-01

    The actions of angiotensin II type 2 receptor (AT2R) and the receptor Mas (MasR) are complex but show similar pronatriuretic function; particularly, AT2R expression and natriuretic function are enhanced in obese/diabetic rat kidney. In light of some reports suggesting a potential positive...... interaction between these receptors, we tested hypothesis that renal AT2R and MasR physically interact and are interdependent to stimulate cell signaling and promote natriuresis in obese rats. We found that infusion of AT2R agonist C21 in obese Zucker rats (OZR) increased urine flow and urinary Na excretion...... coimmunoprecipitated with MasR in cortical homogenate of OZR. Immunoblotting of cortical homogenate cross-linked with zero-length oxidative (sulfhydryl groups) cross-linker cupric-phenanthroline revealed a shift of AT2R and MasR bands upward with overlapping migration for their complexes which were sensitive...

  20. Aquifer test plan for the 100-HR-3 Operable Unit

    International Nuclear Information System (INIS)

    Swanson, L.C.; Hartman, M.J.

    1994-01-01

    This test plan directs hydrologic testing activities planned at three existing Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA) wells in the 100-HR-3 Operable Unit of the Hanford Site. Three additional wells will be installed near these existing wells and used as additional testing arid observation points during the field activities. Figure 1 shows the locations of the three test sites. A primary objective of the testing program is to provide more detailed hydraulic characterization information for the unconfined aquifer and targeted test sites than provided by the initial reconnaissance-level slug testing of Vukelich. A second objective is to evaluate the applicability of slug interference and dipole flow tests for detailed hydraulic characterization in an unconfined aquifer. This aquifer testing program will also be useful for substantiating hydraulic conductivities reported from previous slug tests and evaluating the effects of filter pack volume/configuration on slug test data. Vukelich recommended additional testing to address the latter two issues

  1. Resolving the planetesimal belt of HR 8799 with ALMA

    Science.gov (United States)

    Booth, Mark; Jordán, Andrés; Casassus, Simon; Hales, Antonio S.; Dent, William R. F.; Faramaz, Virginie; Matrà, Luca; Barkats, Denis; Brahm, Rafael; Cuadra, Jorge

    2016-07-01

    The star HR 8799 hosts one of the largest known debris discs and at least four giant planets. Previous observations have found evidence for a warm belt within the orbits of the planets, a cold planetesimal belt beyond their orbits and a halo of small grains. With the infrared data, it is hard to distinguish the planetesimal belt emission from that of the grains in the halo. With this in mind, the system has been observed with ALMA in band 6 (1.34 mm) using a compact array format. These observations allow the inner edge of the planetesimal belt to be resolved for the first time. A radial distribution of dust grains is fitted to the data using an MCMC method. The disc is best fitted by a broad ring between 145^{+12}_{-12} au and 429^{+37}_{-32} au at an inclination of 40^{+5}_{-6}° and a position angle of 51^{+8}_{-8}°. A disc edge at ˜145 au is too far out to be explained simply by interactions with planet b, requiring either a more complicated dynamical history or an extra planet beyond the orbit of planet b.

  2. HR 1362 - A test case for stellar dynamo theories

    International Nuclear Information System (INIS)

    Strassmeier, K.G.; Hall, D.S.; Barksdale, W.S.; Jusick, A.T.; Henry, G.W.

    1990-01-01

    An analysis of 11 yr of photometry of HR 1362 = EK Eri has shown a well-established photometric period of 335 days. This confirms an earlier period determination of about 310 days from 3 yr of APT data and is consistent with a new v sin i determination of 2 + or - 2 km/s. Recent Ca II H and K observations show moderately strong H and K emission lines at a flux level of log F prime (K) of about 6.5 ergs sq m/s. If the photometric period is interpreted as the rotation period, this surface flux is more than one order of magnitude larger than what can be expected from empirical activity versus rotation relationships. The spectrum and the U-B and B-V colors are consistent with a single G8 III-IV spectral classification, while the V-R and V-I values indicate a small color excess, typical of chromospherically active stars. 27 refs

  3. The HR diagram for luminous stars in nearby galaxies

    International Nuclear Information System (INIS)

    Humphreys, R.M.

    1978-01-01

    Due to the extreme faintness of stars in other galaxies it is only possible to sample the brightest stars in the nearest galaxies. The observations must then be compared with comparable data for the brightest stars, the supergiants and O-type stars, in the Milky Way. The data for the luminous stars are most complete for the Milky Way and the Large Magellanic Cloud. The luminosities for the stars in our Galaxy are based on their membership in associations and clusters, and consequently are representative of Population I within approximately 3kpc of the Sun. The data for the stars in the LMC with spectral types O to G8 come from published observations, and the M supergiants are from the author's recent observations of red stars in the LMC. This is the first time that the M supergiants have been included in an HR diagram of the Large Cloud. The presence of the red stars is important for any discussion of the evolution of the massive stars. (Auth.)

  4. MAS-based Distributed Coordinated Control and Optimization in Microgrid and Microgrid Clusters: A Comprehensive Overview

    DEFF Research Database (Denmark)

    Han, Yang; Zhang, Ke; Hong, Li

    2018-01-01

    The increasing integration of the distributed renewable energy sources highlights the requirement to design various control strategies for microgrids (MGs) and microgrid clusters (MGCs). The multi-agent system (MAS)-based distributed coordinated control strategies shows the benefits to balance...... the power and energy, stabilize voltage and frequency, achieve economic and coordinated operation among the MGs and MGCs. However, the complex and diverse combinations of distributed generations in multi-agent system increase the complexity of system control and operation. In order to design the optimized...... configuration and control strategy using MAS, the topology models and mathematic models such as the graph topology model, non-cooperative game model, the genetic algorithm and particle swarm optimization algorithm are summarized. The merits and drawbacks of these control methods are compared. Moreover, since...

  5. Le Kāmasūtra et la « pulsion shastrique » en Inde

    OpenAIRE

    Naudou, Elizabeth

    2013-01-01

    Le mot « shastrique » fait référence au traité (śāstra) d’où sont issus les Kāmasūtra, (plus généralement appelé le Kāmasūtra), « aphorismes sur l’amour » : le Kāmaśāstra, « traité sur l’amour ». Qui dit śāstra, dit, en Inde, exposé religieux ou scientifique, d’où l’expression « pulsion shastrique » que l’on pourrait rendre par « pulsion encyclopédique énumérative et classificatoire ». Le but de cet exposé est de replacer le texte dans cette structure mentale typiquement indienne, qui reflète...

  6. El Proyecto Sismico "LARSE" - Trabajando Hacia un Futuro con Mas Seguridad para Los Angeles

    Science.gov (United States)

    Henyey, Thomas L.; Fuis, Gary S.; Benthien, Mark L.; Burdette, Thomas R.; Christofferson, Shari A.; Clayton, Robert W.; Criley, Edward E.; Davis, Paul M.; Hendley, James W.; Kohler, Monica D.; Lutter, William J.; McRaney, John K.; Murphy, Janice M.; Okaya, David A.; Ryberg, Trond; Simila, Gerald W.; Stauffer, Peter H.

    1999-01-01

    La region de Los Angeles contiene una red de fallas activas, incluyendo muchas fallas por empuje que son profundas y no rompen la superficie de la tierra. Estas fallas ocultas incluyen la falla anteriormente desconocida que fue responsable por la devastacion que ocurrio durante el terremoto de Northridge en enero de 1994, el terremoto mas costoso en la historia de los Estados Unidos. El Experimento Sismico en la Region de Los Angeles (Los Angeles Region Seismic Experiment, LARSE), esta localizando los peligros ocultos de los terremotos debajo de la region de Los Angeles para mejorar la construccion de las estructuras que pueden apoyar terremotos que son inevitables en el futuro, y que ayudaran a los cientificos determinar donde occurira el sacudimento mas fuerte y poderoso.

  7. Mas Gusó: a Roman military Settlement in the suburbium of Emporiae

    Directory of Open Access Journals (Sweden)

    Josep Casas Genover

    2016-11-01

    Full Text Available Although the site of Mas Gusó (province of Girona has been interpreted as a Roman uilla, this is actually a public building. Its existence have to be contextualized within the frame of the structures established by the Roman authority for territorial control closely linked to the creation of a new road network and a tax collection system. We also analyse its survival until the 3rd century AD, which are closely related to the nearby city of Emporiae.

  8. Rotational and translational distortions of the crystal structure of the Sr{sub 2}HrRuO{sub 6} (Hr = Ho, Dy, Gd, Eu) complex perovskites

    Energy Technology Data Exchange (ETDEWEB)

    Triana, C.A., E-mail: ctrianae@unal.edu.co [Grupo de Física de Nuevos Materiales, Departamento de Física, Universidad Nacional de Colombia, A.A. 5997, Bogotá D.C. (Colombia); Landínez Téllez, D.A. [Grupo de Física de Nuevos Materiales, Departamento de Física, Universidad Nacional de Colombia, A.A. 5997, Bogotá D.C. (Colombia); Roa-Rojas, J., E-mail: jroar@unal.edu.co [Grupo de Física de Nuevos Materiales, Departamento de Física, Universidad Nacional de Colombia, A.A. 5997, Bogotá D.C. (Colombia)

    2013-05-15

    Sr{sub 2}HrRuO{sub 6} (Hr = Ho, Dy, Gd, Eu) complex perovskites were synthesized through the high-temperature solid-state reaction method, and their crystal structures were analyzed in detail as a function of the Hr-cation ionic radius. Results of powder XRD pattern measurement and Rietveld analysis of the experimental profiles show that the Sr{sub 2}HrRuO{sub 6} compounds crystallize in a monoclinic distorted perovskite-like structure, P2{sub 1}/n (#14) space group, where the unit cell parameters are related to the primitive unit cell a{sub p} by a≈√(2)a{sub p}, b≈√(2)a{sub p} and c ≈ 2a{sub p}. The structures show an alternate distribution of the Ru{sup 5+} (2d: 0.5, 0, 0) and Hr{sup 3+} (2c: 0, 0.5, 0) making up RuO{sub 6} and HrO{sub 6} octahedra alternatively arranged in two interleaving fcc sublattices, where the O(1), O(2), and O(3) ions are localized at the corner of the octahedral, while the Sr{sup 2+} is located at the A-site, occupying the cavities built by the corner-sharing octahedra with Wyckoff position 4e. Due to the existence of mismatched ionic sizes between the ionic radii of the Sr{sub 2}HrRuO{sub 6} compounds, the HrO{sub 6} and RuO{sub 6} octahedra are constrained to tilting around the [111]{sub c}, [001]{sub c}, and [110]{sub c} cubic directions so as to optimize the Sr–O inter-atomic bond lengths, tending to rotate the structure in order to fix the Ru{sup 5+} and Hr{sup 3+} ions on the M′ and M″ sites of the complex perovskites. The cell parameters a, b, and c, the inter-atomic bond angles, the inter-atomic bond lengths, and the tilting angles increase as the Hr-cation ionic radius increases. The mismatch that exists in the Sr{sub 2}HrRuO{sub 6} ionic radius produces a large distortion from the ideal cubic symmetry. The pure perovskite-like phase of Sr{sub 2}HrRuO{sub 6} is thermodynamically and kinetically stable at high temperatures above 1420 K, where it is entirely governed by the average size of the Hr{sup 3+} and Ru

  9. Rotational and translational distortions of the crystal structure of the Sr2HrRuO6 (Hr = Ho, Dy, Gd, Eu) complex perovskites

    International Nuclear Information System (INIS)

    Triana, C.A.; Landínez Téllez, D.A.; Roa-Rojas, J.

    2013-01-01

    Sr 2 HrRuO 6 (Hr = Ho, Dy, Gd, Eu) complex perovskites were synthesized through the high-temperature solid-state reaction method, and their crystal structures were analyzed in detail as a function of the Hr-cation ionic radius. Results of powder XRD pattern measurement and Rietveld analysis of the experimental profiles show that the Sr 2 HrRuO 6 compounds crystallize in a monoclinic distorted perovskite-like structure, P2 1 /n (#14) space group, where the unit cell parameters are related to the primitive unit cell a p by a≈√(2)a p , b≈√(2)a p and c ≈ 2a p . The structures show an alternate distribution of the Ru 5+ (2d: 0.5, 0, 0) and Hr 3+ (2c: 0, 0.5, 0) making up RuO 6 and HrO 6 octahedra alternatively arranged in two interleaving fcc sublattices, where the O(1), O(2), and O(3) ions are localized at the corner of the octahedral, while the Sr 2+ is located at the A-site, occupying the cavities built by the corner-sharing octahedra with Wyckoff position 4e. Due to the existence of mismatched ionic sizes between the ionic radii of the Sr 2 HrRuO 6 compounds, the HrO 6 and RuO 6 octahedra are constrained to tilting around the [111] c , [001] c , and [110] c cubic directions so as to optimize the Sr–O inter-atomic bond lengths, tending to rotate the structure in order to fix the Ru 5+ and Hr 3+ ions on the M′ and M″ sites of the complex perovskites. The cell parameters a, b, and c, the inter-atomic bond angles, the inter-atomic bond lengths, and the tilting angles increase as the Hr-cation ionic radius increases. The mismatch that exists in the Sr 2 HrRuO 6 ionic radius produces a large distortion from the ideal cubic symmetry. The pure perovskite-like phase of Sr 2 HrRuO 6 is thermodynamically and kinetically stable at high temperatures above 1420 K, where it is entirely governed by the average size of the Hr 3+ and Ru 5+ cations. Highlights: ► Crystal structure of Sr 2 HrRuO 6 (Hr = Ho, Dy, Gd, Eu) as a function of Hr ionic radius. ► XRD

  10. Effectiveness of FitoMas-E in the cultivation of chickpea under two soil moisture levels

    Directory of Open Access Journals (Sweden)

    Yanitza Meriño Hernández

    2018-01-01

    Full Text Available To evaluate the effect of FitoMas-E on the performance of the chickpea, in conditions of drought stress, was the objective of this investigation. An experiment was conducted in the Intensive Garden "Río de Guisa" in the municipality of Guisa during the period from November to February 2014. Four treatments were applied, distributed in a randomized block design with three repetitions, on a "Pardo mullido grisaceo" soil, comparing the application of FitoMas-E under two soil moisture regimes, with and without water stress. The yield of grain and its components were evaluated at the time of harvest maturity, to analyze the responses of these variables to the treatments applied. An analysis of variance was performed using the statistical package STASTISTICA version 8.0 for Windows and the means of the treatments were compared using the Tukey Multiple Range test. The variables that showed a greater response to the treatments imposed were the number of legumes per plant, number of seeds per plant, the mass of 100 seeds and the yield of grain, which ranged between 0.9 and 0.93 t ha-1 for the treatments 2 and 4 respectively. The results obtained in this research showed that the chickpea crop achieved the best productive indicators when the plants were under water stress conditions and received the application of FitoMas-E.

  11. Stanowisko badawcze do oceny efektów utwardzania mas ze szkłem wodnym

    Directory of Open Access Journals (Sweden)

    M. Stachowicz

    2012-12-01

    Full Text Available W pracy przedstawiono wyniki badań nad możliwością zastosowania nowego stanowiska badawczego do oceny, na podstawie końcowejzawartości wody, finalnego efektu utwardzania wybranymi metodami mas ze szkłem wodnym. Badania wykonano na innowacyjnym,mobilnym stanowisku mikrofalowej linii szczelinowej wykorzystującej zjawisko występowania fali stojącej w falowodzie. Badaniompoddano pięć mas sporządzonych z dostępnymi w handlu gatunkami szkła wodnego, które utwardzano trzema, wybranymi metodami:mikrofalową, klasyczną oraz w procesie CO2. Wykazano, na przykładzie mas ze szkłem wodnym, że prezentowane, mobilne stanowiskopomiarowe może, na podstawie określenia końcowej zawartości wody, służyć z powodzeniem do oceny ostatecznego efektu utwardzaniamas formierskich i rdzeniowych.

  12. Do line managers’ have ‘linking pin’ in HR roles?

    Directory of Open Access Journals (Sweden)

    Mohamed Ayyub Hassan

    2015-01-01

    Full Text Available Purpose: The present article aims to identify the possible line managers’ involvement factors in human resource (HR initiatives and its ‘linking pin’ to the HR roles. In this regard, few factors have been considered pertinent to line managers’ involvement factors in HR initiatives which are desire, self-efficacy, and HR support. Whereas, the considered dimensions of HR roles reviewed are strategic partner, change agent, employee champion, and administrative expert. Design/methodology/approach: The paper intends to provide a conceptual review of the past literature in the areas of HR roles and line managers and further justify the proposed conceptual framework that will move this work further. Findings: The review also showed that HR devolution to line managers will boost line managers’ participation and responsibility to practice HR roles at the workplace. Research limitations/implications: The main limitation of this review is no empirical evidence provided by the authors to support the literature of the article. All the provided literature is written based on the findings gained from the previous studies. Practical implications: Line managers’ involvement in HR Initiatives can increase the competency diversity among line manager. This in turn can help the organization to operate at high efficiency. Originality/value: There is a notable lack of research conducted to identify line managers’ involvement in HR. Therefore, this article contributes to the literature on the relationship between line managers and HR roles.

  13. Transgenic mice display hair loss and regrowth overexpressing mutant Hr gene.

    Science.gov (United States)

    Zhu, Kuicheng; Xu, Cunshuan; Zhang, Jintao; Chen, Yingying; Liu, Mengduan

    2017-10-30

    Mutations in the hairless (Hr) gene in both mice and humans have been implicated in the development of congenital atrichia, but the role of Hr in skin and hair follicle (HF) biology remains unknown. Here, we established transgenic mice (TG) overexpressing mutant Hr to investigate its specific role in the development of HF. Three transgenic lines were successfully constructed, and two of them (TG3 and TG8) displayed a pattern of hair loss and regrowth with alternation in the expression of HR protein. The mutant Hr gene inhibited the expression of the endogenous gene in transgenic individuals, which led to the development of alopecia. Interestingly, the hair regrew with the increase in the endogenous expression levels resulting from decreased mutant Hr expression. The findings of our study indicate that the changes in the expression of Hr result in hair loss or regrowth.

  14. THE PRESENCE OF EQUAL OPPORTUNITIES IN HR MANAGEMENT

    Directory of Open Access Journals (Sweden)

    Eva Farkas

    2014-07-01

    Full Text Available Ensuring equal opportunities is a priority for CEO-s and decision makers, however, it is often not put into practice. Changes in recent years along with the priorities of the EU and the efforts made to banish discrimination becoming more prominent brought with themselves a pressure on firms to provide equal opportunities for the different under-privileged social groups. In Hungary the Act CXXV of 2003 on discrimination and equal opportunities lists the groups in need of protection. The law requires employers with more than fifty employees to have an equal opportunities program. In spite of this, these programs are often general and do not implement the changes and goals identified after the assessment. Still, strategies and plans are only worth how much of them are realized. Our article is about the conscious principles of the Hungarian business sector about equality and whether there are regional differences. We compare answers given by both employers and employees on the subject of the extent to which the above mentioned principles are realized by the management and whether the employees experience these changes. Our theory is that the prioritisation of equal opportunities in firms is more the result of access to project funds than that of inner initiative from the firm's management. We analyse our research questions using a quantitative method on a regionally representative national sample. We examined 992 firms with special attention on those and their employees who had some sort of written guidelines on equal opportunities and plans on implementing these. In our paper we give a short review on the importance of equal opportunities, it's manifestation in HR management and it's written declaration, the so called Equal Opportunities Plan (EOP. The efforts of the EU and access to financial resources for the EU projects as a condition our hypotheses are that (1 at least 30% of the firms studied have written guidelines or declaration on equal

  15. In situ high temperature MAS NMR study of the mechanisms of catalysis. Ethane aromatization on Zn-modified zeolite BEA.

    Science.gov (United States)

    Arzumanov, Sergei S; Gabrienko, Anton A; Freude, Dieter; Stepanov, Alexander G

    2009-04-01

    Ethane conversion into aromatic hydrocarbons over Zn-modified zeolite BEA has been analyzed by high-temperature MAS NMR spectroscopy. Information about intermediates (Zn-ethyl species) and reaction products (mainly toluene and methane), which were formed under the conditions of a batch reactor, was obtained by (13)C MAS NMR. Kinetics of the reaction, which was monitored by (1)H MAS NMR in situ at the temperature of 573K, provided information about the reaction mechanism. Simulation of the experimental kinetics within the frames of the possible kinetic schemes of the reaction demonstrates that a large amount of methane evolved under ethane aromatization arises from the stage of direct ethane hydrogenolysis.

  16. Suture-free technique for canine ureteral resection-anastomosis using a microvascular anastomotic system: a cadaveric study.

    Science.gov (United States)

    Wavreille, Vincent; Adin, Christopher A; Arango, Johnattan; Ham, Kathleen L; Byron, Julie K; McLoughlin, Mary A

    2015-01-01

    To describe a suture-free technique for canine ureteral resection-anastomosis using a microvascular anastomotic system (MAS) and to compare surgical time and burst pressure of hand-sewn (HS) ureteral end-to-end anastomosis with the MAS technique. Experimental ex vivo study. Canine cadavers (n = 8). For each cadaver, 1 ureter was randomly assigned to undergo HS anastomosis and the contralateral ureter had MAS anastomosis. The first 3 cadavers (6 ureters) were used to refine the MAS technique. In the other 5 dogs, surgical time and ureteral burst pressure were compared between groups (n = 5 ureters/group). Preliminary procedures showed that selective impaling of the mucosa and submucosa (without muscularis and adventitia) is necessary to allow complete mechanical interlock of the anastomotic rings for the MAS technique. Median anastomotic time was significantly shorter for MAS (7.6 min) than HS (16.6 min; p = .029) and burst pressure higher for MAS (393 cm H2 O) than HS (180 cm H2 O; p = .012). This study demonstrated the feasibility of a suture-free technique of canine ureteral resection-anastomosis using a commercially available MAS. The MAS anastomosis was faster and had higher burst strength compared with the HS anastomosis. © Copyright 2014 by The American College of Veterinary Surgeons.

  17. Daphnia HR96 is a promiscuous xenobiotic and endobiotic nuclear receptor

    Energy Technology Data Exchange (ETDEWEB)

    Karimullina, Elina [Environmental Toxicology Program, Clemson University, Clemson, SC 29634 (United States); Institute of Plant and Animal Ecology, Russian Academy of Sciences, Ural Branch, Yekaterinburg 620144 (Russian Federation); Li Yangchun; Ginjupalli, Gautam K. [Environmental Toxicology Program, Clemson University, Clemson, SC 29634 (United States); Baldwin, William S., E-mail: baldwin@clemson.edu [Environmental Toxicology Program, Clemson University, Clemson, SC 29634 (United States); Biological Sciences, Clemson University, Clemson, SC (United States)

    2012-07-15

    Daphnia pulex is the first crustacean to have its genome sequenced. The genome project provides new insight and data into how an aquatic crustacean may respond to environmental stressors, including toxicants. We cloned Daphnia pulex HR96 (DappuHR96), a nuclear receptor orthologous to the CAR/PXR/VDR group of nuclear receptors. In Drosophila melanogaster, (hormone receptor 96) HR96 responds to phenobarbital exposure and has been hypothesized as a toxicant receptor. Therefore, we set up a transactivation assay to test whether DappuHR96 is a promiscuous receptor activated by xenobiotics and endobiotics similar to the constitutive androstane receptor (CAR) and the pregnane X-receptor (PXR). Transactivation assays performed with a GAL4-HR96 chimera demonstrate that HR96 is a promiscuous toxicant receptor activated by a diverse set of chemicals such as pesticides, hormones, and fatty acids. Several environmental toxicants activate HR96 including estradiol, pyriproxyfen, chlorpyrifos, atrazine, and methane arsonate. We also observed repression of HR96 activity by chemicals such as triclosan, androstanol, and fluoxetine. Nearly 50% of the chemicals tested activated or inhibited HR96. Interestingly, unsaturated fatty acids were common activators or inhibitors of HR96 activity, indicating a link between diet and toxicant response. The omega-6 and omega-9 unsaturated fatty acids linoleic and oleic acid activated HR96, but the omega-3 unsaturated fatty acids alpha-linolenic acid and docosahexaenoic acid inhibited HR96, suggesting that these two distinct sets of lipids perform opposing roles in Daphnia physiology. This also provides a putative mechanism by which the ratio of dietary unsaturated fats may affect the ability of an organism to respond to a toxic insult. In summary, HR96 is a promiscuous nuclear receptor activated by numerous endo- and xenobiotics.

  18. Daphnia HR96 is a promiscuous xenobiotic and endobiotic nuclear receptor

    International Nuclear Information System (INIS)

    Karimullina, Elina; Li Yangchun; Ginjupalli, Gautam K.; Baldwin, William S.

    2012-01-01

    Daphnia pulex is the first crustacean to have its genome sequenced. The genome project provides new insight and data into how an aquatic crustacean may respond to environmental stressors, including toxicants. We cloned Daphnia pulex HR96 (DappuHR96), a nuclear receptor orthologous to the CAR/PXR/VDR group of nuclear receptors. In Drosophila melanogaster, (hormone receptor 96) HR96 responds to phenobarbital exposure and has been hypothesized as a toxicant receptor. Therefore, we set up a transactivation assay to test whether DappuHR96 is a promiscuous receptor activated by xenobiotics and endobiotics similar to the constitutive androstane receptor (CAR) and the pregnane X-receptor (PXR). Transactivation assays performed with a GAL4-HR96 chimera demonstrate that HR96 is a promiscuous toxicant receptor activated by a diverse set of chemicals such as pesticides, hormones, and fatty acids. Several environmental toxicants activate HR96 including estradiol, pyriproxyfen, chlorpyrifos, atrazine, and methane arsonate. We also observed repression of HR96 activity by chemicals such as triclosan, androstanol, and fluoxetine. Nearly 50% of the chemicals tested activated or inhibited HR96. Interestingly, unsaturated fatty acids were common activators or inhibitors of HR96 activity, indicating a link between diet and toxicant response. The omega-6 and omega-9 unsaturated fatty acids linoleic and oleic acid activated HR96, but the omega-3 unsaturated fatty acids alpha-linolenic acid and docosahexaenoic acid inhibited HR96, suggesting that these two distinct sets of lipids perform opposing roles in Daphnia physiology. This also provides a putative mechanism by which the ratio of dietary unsaturated fats may affect the ability of an organism to respond to a toxic insult. In summary, HR96 is a promiscuous nuclear receptor activated by numerous endo- and xenobiotics.

  19. THE HR CHALLENGES IN TOURISM INDUSTRY IN PAKISTAN

    OpenAIRE

    Faiz M. Shaikh; Anwar Ali Shah G. Syed

    2013-01-01

    This research investigates the Human Resource Development in Tourism Industry in Pakistan. The purpose of Human Resource Development is to improve the capacity of the human resource through learning and performance at the individual, process and organizational levels. Data were collected from 300 respondents from Wahi Pandi and their vicinity by using simple random technique and data were analyzed by using SPSS-19 version. It was revealed that problems and constraints, which concern the human...

  20. Variable temperature 127I MAS NMR of β-AgI

    International Nuclear Information System (INIS)

    Wagner, G.W.

    1991-01-01

    Variable temperature 127 I MAS NMR of β-AgI powder, measured from 123 to 413 K is sensitive to Ag + diffusion through the iodine lattice. In low temperature spectra, the iodine ions appear to be in nearly static environments in agreement with the low temperature crystal structure. However, at higher temperatures, substantial broadening of the central transition linewidth is consistent with the presence of two types of Ag + diffusion with activation energies of 0.17 and 0.0080 eV. (author). 15 refs.; 5 figs.; 1 tab

  1. Characterization of new materials in chromatography and fuel cell development by modern NMR techniques; Charakterisierung neuer Materialien in der Chromatographie und Brennstoffzellen-Forschung mit Hilfe moderner NMR-Techniken

    Energy Technology Data Exchange (ETDEWEB)

    Schauff, S.

    2007-12-28

    directly observed using 1H HR-MAS NMR spectroscopy. Changing the mobile phase concentration and composition caused a shift of the broadened peak towards the narrow CH2 signal, resulting in the fusion of both. These effects were explained by two different theories, one of which substantiates with polarity differences, the other with the winding up of the C18 alkyl chains. Separating interactions were also investigated using the suspended-state STD HR-MAS NMR technique that unveiled the part of analyte molecule interacting with the chromatographic sorbent. Furthermore, the molecular recognition of a particulate and a monolithic MIP towards their respective template molecules was investigated using 1H STD HR-MAS NMR spectroscopy. The obtained data proved superiority of the respective MIP over the NIP, and definite knowledge of the interaction site at the analyte molecules could be gained. Differences between specific and non-specific binding could be observed. (orig.)

  2. MODIS Airborne Simulator (MAS) Measurements Taken Onboard the NASAER-2 During the TOGA COARE Intensive Observing Period

    Data.gov (United States)

    National Aeronautics and Space Administration — The TOGA COARE Data Information System has responsibility for distributing information about TOGA COAREdatasets and access paths.The MAS data are available upon...

  3. Isotope ratio measurements of uranium by LA-HR-ICP-MS

    Energy Technology Data Exchange (ETDEWEB)

    Marin, Rafael C.; Sarkis, Jorge E.S., E-mail: rafael.marin@usp.b, E-mail: jesarkis@ipen.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2011-07-01

    This work describes the utilization of Laser Ablation High Resolution Inductively Mass Spectrometry (LA-HR-ICP-MS) technique for the determination of uranium isotope composition in a UO{sub 2} pellet (CRM -125A) supplied and certified by the New Brunswick Laboratory (NBL). To carry out the adjustments of the parameters was used a glass standard NIST 610, supplied and certified by National Institute of Standards and Technology (NIST). The precision of the measurements were improved by adjusting the following parameters: RF power, laser beam diameter, defocusing of laser beam, laser energy, laser energy-density, auxiliary gas and sample gas. The measurements were performed on a continuous ablation with low energy density and defocusing, which demonstrated to be the optimum to reach the best signal stability. Isotope ratios, {sup 234}U/{sup 238}U, {sup 235}U/{sup 238}U and {sup 236}U/{sup 238}U were measured, reaching relative standard deviations (RSD) from 1.55% to 7.60%. The parameters which caused the greatest impact in order to improve the signal stability were RF power, defocusing and laser beam diameter. The results presented by the measurements revealed that the Laser ablation ICP-MS technique offers a rapid and accurate way to perform uranium isotope ratios without any sample preparation, since it allows carrying out the measurements straight on the sample, besides to preserve the testimony that is very important for safeguards and nuclear forensics purposes. (author)

  4. Exposure (mAs) optimisation of a multi-detector CT protocol for hepatic lesion detection: are thinner slices better?

    International Nuclear Information System (INIS)

    Dobeli, Karen L.; Lewis, Sarah J.; Meikle, Steven R.; Brennan, Patrick C.; Thiele, David L.

    2014-01-01

    The purpose of this work was to determine the exposure-optimised slice thickness for hepatic lesion detection with CT. A phantom containing spheres (diameter 9.5, 4.8 and 2.4mm) with CT density 10 HU below the background (50 HU) was scanned at 125, 100, 75 and 50 mAs. Data were reconstructed at 5-, 3- and 1-mm slice thicknesses. Noise, contrast-to-noise ratio (CNR), area under the curve (AUC) as calculated using receiver operating characteristic analysis and sensitivity representing lesion detection were calculated and compared. Compared with the 125 mAs/5mm slice thickness setting, significant reductions in AUC were found for 75 mAs (P<0.01) and 50 mAs (P<0.05) at 1- and 3-mm thicknesses, respectively; sensitivity for the 9.5-mm sphere was significantly reduced for 75 (P<0.05) and 50 mAs (P<0.01) at 1-mm thickness; sensitivity for the 4.8-mm sphere was significantly lower for 100, 75 and 50 mAs at all three slice thicknesses (P<0.05). The 2.4-mm sphere was rarely detected. At each slice thickness, noise at 100, 75 and 50 mAs exposures was approximately 10, 30 and 50% higher, respectively, than that at 125 mAs exposure. CNRs decreased in an irregular manner with reductions in exposure and slice thickness. This study demonstrated no advantage to using slices below 5mm thickness, and consequently thinner slices are not necessarily better.

  5. Studies on the intracellular localization of hHR23B

    International Nuclear Information System (INIS)

    Katiyar, Samiksha; Lennarz, William J.

    2005-01-01

    Yeast Rad23, originally identified as a DNA repair protein, has been proposed to participate in other cellular functions, i.e., the proteasome-degradation pathway, the process of spindle pole body duplication and as a component of the anaphase checkpoint. Two human homologs of yeast Rad23, hHR23A and hHR23B, exhibit high sequence homology with yRad23 and also have been shown to be involved in DNA repair and proteasome-dependent degradation. Previous studies on the intracellular localization of hHR23A and hHR23B revealed their predominant localization in the nucleus during interphase and in the cytoplasm during mitosis. We have analyzed the localization of hHR23B during all the phases of the cell cycle using immunofluorescence. Unlike previous studies, our results suggest localization of hHR23B in the nucleus as well as in the cytoplasm during G1 phase. The nuclear levels of hHR23B decrease during S-phase of the cell cycle. When the cell enters mitosis, hHR23B relocalizes in the cytoplasm without association with chromatin. These results indicate that the intracellular distribution hHR23B is cell cycle dependent

  6. DID FOMALHAUT, HR 8799, AND HL TAURI FORM PLANETS VIA THE GRAVITATIONAL INSTABILITY? PLACING LIMITS ON THE REQUIRED DISK MASSES

    International Nuclear Information System (INIS)

    Nero, D.; Bjorkman, J. E.

    2009-01-01

    Disk fragmentation resulting from the gravitational instability has been proposed as an efficient mechanism for forming giant planets. We use the planet Fomalhaut b, the triple-planetary system HR 8799, and the potential protoplanet associated with HL Tau to test the viability of this mechanism. We choose the above systems since they harbor planets with masses and orbital characteristics favored by the fragmentation mechanism. We do not claim that these planets must have formed as the result of fragmentation, rather the reverse: if planets can form from disk fragmentation, then these systems are consistent with what we should expect to see. We use the orbital characteristics of these recently discovered planets, along with a new technique to more accurately determine the disk cooling times, to place both lower and upper limits on the disk surface density-and thus mass-required to form these objects by disk fragmentation. Our cooling times are over an order of magnitude shorter than those of Rafikov, which makes disk fragmentation more feasible for these objects. We find that the required mass interior to the planet's orbital radius is ∼0.1 M sun for Fomalhaut b, the protoplanet orbiting HL Tau, and the outermost planet of HR 8799. The two inner planets of HR 8799 probably could not have formed in situ by disk fragmentation.

  7. El medievalismo fértil de Paloma Díaz-Mas

    Directory of Open Access Journals (Sweden)

    Rafael M. Mérida Jiménez

    2001-01-01

    Full Text Available The author of this article is concerned with trying to understand why Paloma Díaz-Mas, the writer of such an excellent novel as La tierra fértil (1999, has not received much critical attention. He underlines three main reasons. First, she does not live in Madrid or Barcelona and so she is far away from the main centres of cultural power. Second, she teaches Spanish literature in the Basque Country, a political and linguistic community which significantly differs from that of many other writers. Third, she writes historical novels, which does not appear to be very fashionable in Spain these days. Moreover, Díaz-Mas is a woman writer who does not make use of the most commonly available feminine patterns, and she does not seem to offer a model easy to include in a given feminist methodology either. However, Mérida-Jiménez argues that Paloma provides an intelligent deconstruction of “male authority” through subtle rhetorical means, as well as a representation of the weakness of his “domination” in very innovative ways, such as those derived from the dialectics between history and fiction, centrality and marginality, heterosexuality and homosexuality, individual and society, dream and reason or tradition and modernity.

  8. Active and passive fire protection system in academic building KH. Mas Mansur, Islamic University of Indonesia

    Directory of Open Access Journals (Sweden)

    Suryoputro M. Ragil

    2018-01-01

    Full Text Available According to the theory of fire triangle, the existence of combustible materials, heat, and oxygen can cause fire disaster. KH. Mas Mansur building, Islamic University of Indonesia has a fire protection, but rarely to be checked regularly and the number of equipment is less standard as well as the lack of an evacuation route map to facilitate the evacuation process. Inside the building also does not provide safety signs such as the evacuation directions, exit, and warning in case of fire. Therefore, researchers analysed the infrastructure of prevention and control in the building KH. Mas Mansur. Researchers used the method of observation, interviews, and checklist to know the condition directly, and compare with the standard regulations. Results concordance rate of existing infrastructure is 67% fire extinguisher, hydrant box 56%, 71% alarms, sprinkler 0%, 40% detectors, emergency doors 71%, 50% emergency stairs, assembly point 0% and directions 0%. The current results were below the standard of at least 80%. As for recommendations, researchers create a new evacuation map then put the existing infrastructure according to standard regulations, and it had consulted with the specialist of Occupational Safety and Health in the field of fire.

  9. MODELAGEM DE UM SISTEMA MULTIAGENTE DE APOIO À PBL UTILIZANDO A METODOLOGIA MAS-COMMONKADS+

    Directory of Open Access Journals (Sweden)

    Laysa Mabel de Oliveira Fontes

    2014-10-01

    Full Text Available A aprendizagem baseada em problema (Problem-Based Learning - PBL é um método no qual os estudantes aprendem através da resolução de um problema que, em geral, não possui uma solução trivial e uma única solução correta. A PBL destaca o trabalho em equipe como um dos principais requisitos para o sucesso do processo de aprendizagem, ou seja, a colaboração é essencial. No entanto, a implantação de um método de ensino com base na PBL não é uma tarefa trivial. Em Ambientes Virtuais de Aprendizagem (AVAs, a complexidade de implantação deste método é ainda maior, pois o facilitador nem sempre pode detectar possíveis problemas na colaboração, nem possui todas as informações necessárias para aplicar as técnicas de aprendizagem deste método. Desta forma, este artigo apresenta o processo de modelagem de um Sistema Multiagente (SMA de apoio à PBL. O SMA proposto foi modelado utilizando a metodologia MAS-CommonKADS+, que consiste em uma extensão da metodologia MAS-CommonKADS.

  10. ANALISIS PERHITUNGAN DAN PELAPORAN PAJAK PERTAMBAHAN NILAI PADA PT FAJAR MAS KARYATAMA

    Directory of Open Access Journals (Sweden)

    MARINDO PUTRA

    2017-05-01

    Full Text Available Value Added Tax (VAT is Tax that imposed on any apreciation in value of the goods or services in its circulation from producers to consumers. Through the calculation dan reporting is good, then the company may be said it has complied with the applicable rules in order to enhance the national development budget of the Government. PT Fajar Mas Karyatama as a company engaged intrade of goods subject to VAT, as in general make a purchase with Input Tax which may be credited. The purpose of this study to know whether the application of VAT and VAT underpayment or overpayment in accordance with law of VAT No. 42 of 2009. This study used a comparative method. The company will account for and report the delivery of Added Value Tax in the Notice Period of Added Value Tax (VAT Period SPT. VAT calculations made by company are the basis for the report required to implement Tax Laws for the companies. Conclusion is that application of VAT in the calculating and reporting of PT Fajar Mas Karyatama was almost accordance with the VAT Act applied and through the application of VAT, namely the purchase and sale of Taxable Goods so that the sum of the difference by the number of Input Tax or Output Tax generate VAT Less/More Pay at the end each mont, it is accordance with the Law of VAT No. 42 of 2009.

  11. Quality of Milk Pasteurized Produced By UD. Gading Mas During Storage in Refrigerator

    Directory of Open Access Journals (Sweden)

    Manik Eirry Sawitri

    2012-02-01

    Full Text Available The aim of this research was to study pasteurized milk quality produced by UD. Gading Mas on pH, Acidity, alcohol test and TPC during 5 days storage in refrigerator. On first day showed that  weight mass 1,06 (w/w; fat content 2,00 (g/100g,  protein content 3,02  (g/100g, Zn 1,67 ppm, Cu<0,005 ppm, Pb 0,02 ppm,  As  0,0120 ppm, Hg< 0,0002 ppm, Sn 1,60 ppm dan Cd < 0,001 ppm and organoleptic test included color, flavor and taste were normal. Pasteurized milk characteristic during 5 days refrigeration for pH were 6,57;6,58;6,73;6,60 and 6,50 respectively. Acidity were 1,147 %, 0,145 %, 0,145%, 0,157 %, 0,156 % and 0,175  % respectively. TPC were 6,16 x 101, 1,2. 104; 3,15.104, 0,42.106 and 3,5.108 respectively. It concluded that pasteurized milk produced by UD Gading Mas fulfilled SNI quality standard based on weight mass, pH, acidity, fat, protein, heavy metal content, organoleptic test and TPC.   Keywords: pasteurized milk, quality, refrigerator

  12. Elektroniskās naudas sistēmas WebMoney

    OpenAIRE

    Zablocka, Jelena

    2011-01-01

    Šī darba mērķis ir pamatojoties uz speciālo literatūru un pieejamu statistisko informāciju izskatīt jautājumu par elektroniskās naudas būtību, raksturot un parādīt tās veidus, analizēt un izskatīt elektroniskās naudas izmantošanas problēmas, izpētīt un norādīt tās izmantošanas perspektīvas, novērtēt tās uzskaites un kontroles operāciju problēmas, kas ir sastopamas, izmantojot elektronisko naudu praksē. Darbs sastāv no 5 nodaļām. Pirmajā nodaļā aplūkoti elektroniskās naudas jēdziens un ...

  13. THE HR CHALLENGES IN TOURISM INDUSTRY IN PAKISTAN

    Directory of Open Access Journals (Sweden)

    Faiz M. Shaikh

    2013-03-01

    Full Text Available This research investigates the Human Resource Development in Tourism Industry in Pakistan. The purpose of Human Resource Development is to improve the capacity of the human resource through learning and performance at the individual, process and organizational levels. Data were collected from 300 respondents from Wahi Pandi and their vicinity by using simple random technique and data were analyzed by using SPSS-19 version. It was revealed that problems and constraints, which concern the human resource development in the Tourism Industry, viz., shortage of qualified manpower; shortage of tourism training infrastructure and qualified trainers; working conditions in the Tourism Industry; and lack of proper strategies and policies for human resource development. The present study is an attempt to analyze the HRD initiatives of Tourism Industry with special reference to Gorrakh Hill.

  14. Increasing brain angiotensin converting enzyme 2 activity decreases anxiety-like behavior in male mice by activating central Mas receptors.

    Science.gov (United States)

    Wang, Lei; de Kloet, Annette D; Pati, Dipanwita; Hiller, Helmut; Smith, Justin A; Pioquinto, David J; Ludin, Jacob A; Oh, S Paul; Katovich, Michael J; Frazier, Charles J; Raizada, Mohan K; Krause, Eric G

    2016-06-01

    Over-activation of the brain renin-angiotensin system (RAS) has been implicated in the etiology of anxiety disorders. Angiotensin converting enzyme 2 (ACE2) inhibits RAS activity by converting angiotensin-II, the effector peptide of RAS, to angiotensin-(1-7), which activates the Mas receptor (MasR). Whether increasing brain ACE2 activity reduces anxiety by stimulating central MasR is unknown. To test the hypothesis that increasing brain ACE2 activity reduces anxiety-like behavior via central MasR stimulation, we generated male mice overexpressing ACE2 (ACE2 KI mice) and wild type littermate controls (WT). ACE2 KI mice explored the open arms of the elevated plus maze (EPM) significantly more than WT, suggesting increasing ACE2 activity is anxiolytic. Central delivery of diminazene aceturate, an ACE2 activator, to C57BL/6 mice also reduced anxiety-like behavior in the EPM, but centrally administering ACE2 KI mice A-779, a MasR antagonist, abolished their anxiolytic phenotype, suggesting that ACE2 reduces anxiety-like behavior by activating central MasR. To identify the brain circuits mediating these effects, we measured Fos, a marker of neuronal activation, subsequent to EPM exposure and found that ACE2 KI mice had decreased Fos in the bed nucleus of stria terminalis but had increased Fos in the basolateral amygdala (BLA). Within the BLA, we determined that ∼62% of GABAergic neurons contained MasR mRNA and expression of MasR mRNA was upregulated by ACE2 overexpression, suggesting that ACE2 may influence GABA neurotransmission within the BLA via MasR activation. Indeed, ACE2 overexpression was associated with increased frequency of spontaneous inhibitory postsynaptic currents (indicative of presynaptic release of GABA) onto BLA pyramidal neurons and central infusion of A-779 eliminated this effect. Collectively, these results suggest that ACE2 may reduce anxiety-like behavior by activating central MasR that facilitate GABA release onto pyramidal neurons within the

  15. The Structure of the Fantômas Novel Series by Pierre Souvestre and Marcel Allain and the Problem of Seriality in Popular Literature

    Directory of Open Access Journals (Sweden)

    Kirill A. Chekalov

    2017-12-01

    Full Text Available The essay examines the structure of a 32-volume series of Fantômas novels created by Pierre Souvestre and Marcel Allain; it traces the origins and development of the serial genre and generic novelties related to seriality. The latter include a relative autonomy of each story in each volume and interconnection of the volumes via the figure of the criminal “slipping away” from the hands of justice. The study compares poetological techniques of the fabula development and points out specific features of the Belle époque reality as represented through the introduction of recognizable “cultural signs,” varia- tions of everyday incidents, and newspaper chronicle of criminal events. It also analyzes the image of Fantômas and other recurrent characters of the series (such as Juve, Fan- dor, Hélène, Lady Maud Beltham, etc. The authors examine para-literary features that can be traced in many other different forms such as TV series and graphic novels. They include (1 mythologization of the main character as embodiment of Evil, or a “criminal genius”; (2 confusion of the real and the fictional, verisimilar and extraordinary, horri- ble and comic based on the variations of literary and journalistic clichés; (3 repetition of plot patterns, (4 attempts to guess and to meet reader’s expectations.

  16. Research on the theory and methodology of integrating GIS and MAS and its application in simulating of pedestrians flows in a crowd's activity centre of Shanghai metropolitan

    Science.gov (United States)

    Liu, Miaolong; Chen, Peng

    2006-10-01

    Based on the development trend of research on urban morphology and its evolution from macro scale to micro scale, a new tight-coupling integrating method of GIS and MAS has been discussed briefly in this paper. After analyzing the characteristics and mechanism of pedestrian's flows in a crowds' activity center in a metropolitan, a prototype and mathematical expression of pedestrian's flows simulation have been put forward in the paper. A few key expressions and techniques for treating the specific behaviors of pedestrians flows, especially how the individuals of the flows make a decision to follow a original designed direction, how to make a decision whether stop or change his movement and select a new direction when the individuals meet a obstacle have been explored and discussed in detail. Using some tools provided by general GIS systems (such as ArcGIS 9) and a few specific programming languages, a new software system integrating GIS and MAS applicable for simulating pedestrians flows in a crowd activity centre has been developed successfully. Under the environment supported by the software system, as an applicable case, a dynamic evolution process of the pedestrian's flows (dispersed process for the spectators) in a crowds' activity center - The Shanghai Stadium has been simulated successfully. The successful simulating of a case of emergence when one or more exits emerge accidents will be very useful for managing and treating crowds' safety in a lot of assembling centers. At the end of the paper, some new research problems have been pointed out for the future.

  17. Determination of structural topology of a membrane protein in lipid bilayers using polarization optimized experiments (POE) for static and MAS solid state NMR spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Mote, Kaustubh R. [University of Minnesota, Department of Chemistry (United States); Gopinath, T. [University of Minnesota, Department of Biochemistry, Molecular Biology and Biophysics (United States); Veglia, Gianluigi, E-mail: vegli001@umn.edu [University of Minnesota, Department of Chemistry (United States)

    2013-10-15

    The low sensitivity inherent to both the static and magic angle spinning techniques of solid-state NMR (ssNMR) spectroscopy has thus far limited the routine application of multidimensional experiments to determine the structure of membrane proteins in lipid bilayers. Here, we demonstrate the advantage of using a recently developed class of experiments, polarization optimized experiments, for both static and MAS spectroscopy to achieve higher sensitivity and substantial time-savings for 2D and 3D experiments. We used sarcolipin, a single pass membrane protein, reconstituted in oriented bicelles (for oriented ssNMR) and multilamellar vesicles (for MAS ssNMR) as a benchmark. The restraints derived by these experiments are then combined into a hybrid energy function to allow simultaneous determination of structure and topology. The resulting structural ensemble converged to a helical conformation with a backbone RMSD {approx}0.44 A, a tilt angle of 24 Degree-Sign {+-} 1 Degree-Sign , and an azimuthal angle of 55 Degree-Sign {+-} 6 Degree-Sign . This work represents a crucial first step toward obtaining high-resolution structures of large membrane proteins using combined multidimensional oriented solid-state NMR and magic angle spinning solid-state NMR.

  18. From Admin to Strategy: The Changing Face of the HR Function. IES Report 332.

    Science.gov (United States)

    Tamkin, Penny; And Others

    Evidence from academic research and management experts in the United Kingdom and elsewhere confirms that the recent focus in work organizations on cost reductions through downsizing has changed the roles and structures of many human resources (HR) units. HR units have had to prove their contribution to the organization's bottom line, raise their…

  19. Comparison between Pentacam HR and Orbscan II after hyperopic photorefractive keratectomy

    Directory of Open Access Journals (Sweden)

    Mahmoud Jabbarvand

    2017-01-01

    Conclusion: Pentacam HR and Orbscan II after PRK for hyperopia show reasonable agreement for determining A-BFS, P-BFS, A-TG3, and CCT, but not for A-CE, P-CE, A-TG5, or ACD. CCT measurements with Pentacam HR have reasonable agreement with US pachymetry.

  20. Data-driven HR how to use analytics and metrics to drive performance

    CERN Document Server

    Marr, Bernard

    2018-01-01

    Traditionally seen as a purely people function unconcerned with numbers, HR is now uniquely placed to use company data to drive performance, both of the people in the organization and the organization as a whole. Data-driven HR is a practical guide which enables HR practitioners to leverage the value of the vast amount of data available at their fingertips. Covering how to identify the most useful sources of data, how to collect information in a transparent way that is in line with data protection requirements and how to turn this data into tangible insights, this book marks a turning point for the HR profession. Covering all the key elements of HR including recruitment, employee engagement, performance management, wellbeing and training, Data-driven HR examines the ways data can contribute to organizational success by, among other things, optimizing processes, driving performance and improving HR decision making. Packed with case studies and real-life examples, this is essential reading for all HR profession...

  1. How the impact of HR practices on employee well-being and performance changes with age

    NARCIS (Netherlands)

    Kooij, T.A.M.; Guest, D.; Clinton, M.; Knight, T.; Jansen, P.G.W.; Dikkers, J.S.E.

    2013-01-01

    With changing retirement ages and an aging workforce, interest is growing on the potential contribution of relevant bundles of HR practices in eliciting well-being and performance among aging workers. Drawing on theories on lifespan development and self-regulation, we distinguished two bundles of HR

  2. Distribution of ABO and Rh-Hr blood group antigens, alleles and ...

    African Journals Online (AJOL)

    ABO and Rh-Hr blood group antigens represent a genetically stably determined trait with many-sided biological and clinical significance. The indigenous Ajarian population (105 subjects) was investigated for ABO Rh-Hr red cell blood group antigens. Using immunoserologic methods, seven blood group antigens (A, B, C, c, ...

  3. How the impact of HR Practices on employee well-being and performance changes with age

    NARCIS (Netherlands)

    Kooij, T.A.M.; Guest, D.; Clinton, M.; Knight, T.; Jansen, P.G.W.; Dikkers, J.S.E.

    2013-01-01

    With changing retirement ages and an aging workforce, interest is growing on the potential contribution of relevant bundles of HR practices in eliciting well-being and performance among aging workers. Drawing on theories on lifespan development and self-regulation, we distinguished two bundles of HR

  4. New marine commons along the Chilean coast – the management areas (MAs of Peñuelas and Chigualoco

    Directory of Open Access Journals (Sweden)

    Gloria L. Gallardo Fernández

    2011-09-01

    Full Text Available To halt degradation of benthic resources in Chile, management areas (MAs were set up under the Territorial Use Rights in Fisheries (TURFs framework in the late 1990s. Integrated into the global market, MAs have since expanded along the Chilean coast, involving thousands of small-scale artisanal fishers. This paper analyses how economic criteria relates to social and ecological performance of Chilean MAs, by applying TURFs, commons and co-management theory to two cases: MAs Peñuelas and Chigualoco. To collect and analyse data Participatory Rural Appraisal tools, interviews and official statistics and reports were used. Our results show that MAs’ economic benefits are connected to fluctuations on the global market. Adapting to changing world market prices then becomes paramount. TURFs’ main goal is ecological conservation, but achieving this seems to depend on meeting fishers’ livelihoods; failure to do so likely results in failure to meet conservation objectives. A serious weakness of the Chilean TURFs system is that it does not pay enough attention to fishers’ livelihoods or to the global market context. Furthermore, there is a strong relationship between good economic benefits and social sustainability. But irrespective of economic performance, fisher organizations have been empowered and gained increased resource control with the TURFs system. At policy level, a differentiated and more flexible system could be more suitable for existing heterogeneous MAs and their particular economic, social and ecological challenges. For improved economic sustainability and resource conservation, a system with multiple-species managing MAs could be promoted as well. Finally, to enhance theory of commons, co-management and TURFs, we argue for greater acknowledgement of TURFs’ social benefits in addition to economic assessments. More attention should also be paid to global market conditions of which MAs are dependent and in which they are embedded

  5. Lipid bilayer-bound conformation of an integral membrane beta barrel protein by multidimensional MAS NMR

    International Nuclear Information System (INIS)

    Eddy, Matthew T.; Su, Yongchao; Silvers, Robert; Andreas, Loren; Clark, Lindsay; Wagner, Gerhard; Pintacuda, Guido; Emsley, Lyndon; Griffin, Robert G.

    2015-01-01

    The human voltage dependent anion channel 1 (VDAC) is a 32 kDa β-barrel integral membrane protein that controls the transport of ions across the outer mitochondrial membrane. Despite the determination of VDAC solution and diffraction structures, a structural basis for the mechanism of its function is not yet fully understood. Biophysical studies suggest VDAC requires a lipid bilayer to achieve full function, motivating the need for atomic resolution structural information of VDAC in a membrane environment. Here we report an essential step toward that goal: extensive assignments of backbone and side chain resonances for VDAC in DMPC lipid bilayers via magic angle spinning nuclear magnetic resonance (MAS NMR). VDAC reconstituted into DMPC lipid bilayers spontaneously forms two-dimensional lipid crystals, showing remarkable spectral resolution (0.5–0.3 ppm for 13 C line widths and <0.5 ppm 15 N line widths at 750 MHz). In addition to the benefits of working in a lipid bilayer, several distinct advantages are observed with the lipid crystalline preparation. First, the strong signals and sharp line widths facilitated extensive NMR resonance assignments for an integral membrane β-barrel protein in lipid bilayers by MAS NMR. Second, a large number of residues in loop regions were readily observed and assigned, which can be challenging in detergent-solubilized membrane proteins where loop regions are often not detected due to line broadening from conformational exchange. Third, complete backbone and side chain chemical shift assignments could be obtained for the first 25 residues, which comprise the functionally important N-terminus. The reported assignments allow us to compare predicted torsion angles for VDAC prepared in DMPC 2D lipid crystals, DMPC liposomes, and LDAO-solubilized samples to address the possible effects of the membrane mimetic environment on the conformation of the protein. Concluding, we discuss the strengths and weaknesses of the reported

  6. Change of offices for HR Department - disrupted service during the last week of February 2013

    CERN Multimedia

    2013-01-01

    HR Department would like to inform that, due to office renovation work, a number of HR Services currently located on the ground, first and second floors of Building 5 will move to temporary offices as from late February.   The removals will take place from Friday 22 until Tuesday 26 February 2013 inclusive and during this period, telephone and e-mail contact may be disrupted. The following services will be relocated to: Building 510  – ground floor (until mid-June) Head of Department and Deputy Office of the Head of HR Department Group Leaders and Partners Diversity Office HR Legal Section Building 652 – Prefab/Algeco (until September) Human Resources Advisors and assistants Staff Recruitment Service Fellows & Apprentices Service Students & Associates Service Temporary office numbers will be available in the CERN phonebook. Any emergencies during the removals may be addressed to Lynda.Leroux@cern.ch Thank you in advance for your understanding. HR Head O...

  7. Exploring the central characteristics of HR shared services: evidence from a critical case study in the Netherlands

    NARCIS (Netherlands)

    Meijerink, Jeroen Gerard; Bondarouk, Tatiana

    2012-01-01

    Human resource shared service centers (HR SSCs) are foreseen as improving HR service delivery for their end-users: employees, line managers and decentralized HR professionals. Although the concept expects the benefits of HR SSCs to come from centralizing knowledge and decentralizing the control

  8. Dislocation Interactions in Olivine Revealed by HR-EBSD

    Science.gov (United States)

    Wallis, David; Hansen, Lars N.; Britton, T. Ben; Wilkinson, Angus J.

    2017-10-01

    Interactions between dislocations potentially provide a control on strain rates produced by dislocation motion during creep of rocks at high temperatures. However, it has been difficult to establish the dominant types of interactions and their influence on the rheological properties of creeping rocks due to a lack of suitable observational techniques. We apply high-angular resolution electron backscatter diffraction to map geometrically necessary dislocation (GND) density, elastic strain, and residual stress in experimentally deformed single crystals of olivine. Short-range interactions are revealed by cross correlation of GND density maps. Spatial correlations between dislocation types indicate that noncollinear interactions may impede motion of proximal dislocations at temperatures of 1000°C and 1200°C. Long-range interactions are revealed by autocorrelation of GND density maps. These analyses reveal periodic variations in GND density and sign, with characteristic length scales on the order of 1-10 μm. These structures are spatially associated with variations in elastic strain and residual stress on the order of 10-3 and 100 MPa, respectively. Therefore, short-range interactions generate local accumulations of dislocations, leading to heterogeneous internal stress fields that influence dislocation motion over longer length scales. The impacts of these short- and/or long-range interactions on dislocation velocities may therefore influence the strain rate of the bulk material and are an important consideration for future models of dislocation-mediated deformation mechanisms in olivine. Establishing the types and impacts of dislocation interactions that occur across a range of laboratory and natural deformation conditions will help to establish the reliability of extrapolating laboratory-derived flow laws to real Earth conditions.

  9. Low dose multi-detector CT of the chest (iLEAD Study): Visual ranking of different simulated mAs levels

    International Nuclear Information System (INIS)

    Ley-Zaporozhan, Julia; Ley, Sebastian; Krummenauer, Frank; Ohno, Yoshiharu; Hatabu, Hiroto; Kauczor, Hans-Ulrich

    2010-01-01

    Purpose: Detailed evaluation of the lung parenchyma might be impaired by use of low dose CT as image noise increases and subsequently image quality decreases. The aim of our study was to determine the accuracy of visual perception of differences in image quality and noise at low dose chest CT. Materials and methods: Forty-four patients suffering from emphysema underwent CT (Aquilion-16, 120 kV, 150 mAs, 1 mm-collimation). Original raw data were used for simulation of 10 different mAs settings from 10 mAs to 100 mAs in 10 mAs increments. Three representative hard copy images (carina, 4 cm above, 5 cm below) were printed for evaluation of lung parenchyma (high-resolution kernel, lung window) and mediastinum (soft-kernel, soft tissue window). Ranking of expected low mAs level was performed for lung and soft tissue separately based on visual perception by three-blinded chest radiologist independently. Results were compared to the real simulated mAs. Results: The accuracy for correct ranking of the original 150 mAs scan was 89% for lung and 86% for soft tissue while it was 99% for the simulated 10 mAs for both windows. In comparison to the lowest mAs a significant error increase was found for the lung at 60-100 mAs (with error increase of 30-47%) for reader-I; 60-100 mAs for (33-64%) for reader-II and 70-100 mAs (38-57%) for reader-III. For the soft tissue: 60-150 mAs (with error increase of 28-63%) for reader-I; 50-100 mAs (35-56%) for reader-II and 50-90 mAs (35-40%) for reader-III. Conclusion: Simulated dose levels below 60 mAs (=42 mAs eff ) were clearly differentiated from higher dose levels by all readers. Therefore, imaging doses could be lowered down to 60 mAs without a diagnostically relevant increase in noise impairing image quality.

  10. Premises and Limitations in Defining and Measuring Synergy from M&As

    Directory of Open Access Journals (Sweden)

    Aevoae George Marian

    2017-01-01

    Full Text Available Mergers and acquisitions are performed worldwide mainly because of synergy. Although many invoke the term synergy as the key motivation of why they engage in M&As, research has led us to understand that it is not very clear in terms of what it actually is. In the scientific literature, synergy is mostly defined as being “2+2=5”. Thus, we first thought that it can only be a positive effect. But, latter on, we found out that synergy is not only positive, it can be negative as well, known as negative synergy or dyssynergy. The purpose of this paper is to shed some light on what is synergy, how can we quantify and classify it and why acquiring firms tend to pay more for the target firm. We believe that there is a link between the amount of premium paid for a target firm and the expectations for synergy.

  11. 1H CSA parameters by ultrafast MAS NMR: Measurement and applications to structure refinement.

    Science.gov (United States)

    Miah, Habeeba K; Cresswell, Rosalie; Iuga, Dinu; Titman, Jeremy J

    2017-10-01

    A 1 H anisotropic-isotropic chemical shift correlation experiment which employs symmetry-based recoupling sequences to reintroduce the chemical shift anisotropy in ν 1 and ultrafast MAS to resolve 1 H sites in ν 2 is described. This experiment is used to measure 1 H shift parameters for L-ascorbic acid, a compound with a relatively complex hydrogen-bonding network in the solid. The 1 H CSAs of hydrogen-bonded sites with resolved isotropic shifts can be extracted directly from the recoupled lineshapes. In combination with DFT calculations, hydrogen positions in crystal structures obtained from X-ray and neutron diffraction are refined by comparison with simulations of the full two-dimensional NMR spectrum. The improved resolution afforded by the second dimension allows even unresolved hydrogen-bonded sites 1 H to be assigned and their shift parameters to be obtained. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. Adding real data to detect emotions by means of smart resource artifacts in MAS

    Directory of Open Access Journals (Sweden)

    Jaime RINCÓN

    2016-12-01

    Full Text Available This article proposes an application of a social emotional model, which allows to extract, analyse, represent and manage the social emotion of a group of entities. Specifically, the application is based on how music can influence in a positive or negative way over emotional states. The proposed approach employs the JaCalIVE framework, which facilitates the development of this kind of environments. A physical device called smart resource offers to agents processed sensor data as a service. So that, agents obtain real data from a smart resource. MAS uses the smart resource as an artifact by means of a specific communications protocol. The framework includes a design method and a physical simulator. In this way, the social emotional model allows the creation of simulations over JaCalIVE, in which the emotional states are used in the decision-making of the agents.

  13. Marrero Regalado y Aguiar: El arte masónico oficial de la Postguerra en Canarias

    Directory of Open Access Journals (Sweden)

    David Martín López

    2008-12-01

    Full Text Available La masonería, como institución filantrópica y bien asentada durante la II República en España, fue totalmente rechazada por Franco desde su Alzamiento de 1936. Sin embargo, la protección oficial de la masonería en Canarias hizo que artistas masones como José Aguiar o como el arquitecto Marrero Regalado pudieran materializar su estética en numerosos proyectos para un nuevo Estado, en el que la concepción masónica del Ser Humano aparece como lenguaje encubierto y subversivo.

  14. Understanding deformation with high angular resolution electron backscatter diffraction (HR-EBSD)

    Science.gov (United States)

    Britton, T. B.; Hickey, J. L. R.

    2018-01-01

    High angular resolution electron backscatter diffraction (HR-EBSD) affords an increase in angular resolution, as compared to ‘conventional’ Hough transform based EBSD, of two orders of magnitude, enabling measurements of relative misorientations of 1 x 10-4 rads (~ 0.006°) and changes in (deviatoric) lattice strain with a precision of 1 x 10-4. This is achieved through direct comparison of two or more diffraction patterns using sophisticated cross-correlation based image analysis routines. Image shifts between zone axes in the two-correlated diffraction pattern are measured with sub-pixel precision and this realises the ability to measure changes in interplanar angles and lattice orientation with a high degree of sensitivity. These shifts are linked to strains and lattice rotations through simple geometry. In this manuscript, we outline the basis of the technique and two case studies that highlight its potential to tackle real materials science challenges, such as deformation patterning in polycrystalline alloys.

  15. Indigenous development of 20 Cu. M/hr flat linear induction pump (Paper No. 047)

    Energy Technology Data Exchange (ETDEWEB)

    Prabhakar, R; Prakash, V; Sundarasekaran, S

    1987-01-01

    A distinctive physical property of sodium metal which is used as a coolant in fast reactors, is its high electrical conductivity. This together with its ability to wet stainless steel permits fluid pumping techniques using electromagnetic devices. Electromagnetic pumps are analogous to the electric motor, in which a force is produced by the interaction of magnetic field and current flowing in a conductor. Flat linear induction pump (FLIP) whose operating principle is similar to that of an induction motor is one of the types of electromagnetic pumps in wide use in auxilary circuits of fast reactors. As part of efforts to develop fast reactor components indigenously, work on the design and construction of a prototype FLIP rated for 20Cu.M/hr and 5Kg/sq.cm at 550degC was initiated. Under Board of Research in Nuclear Sciences scheme, the design was carried out by the Electrical Engineering Department of IIT, Madras. Pump was constructed at Engineering Development Division, Indira Gandhi Centre for Atomic Research, Kalpakkam. This paper presents in detail the work carried out for the fabrication of flow channel and for the stator assembly. Results obtained from dry electrical tests are also reported. Appendix summarises the design data. (author).

  16. Badania jakości regeneratu ze zużytych mas ze spoiwem organicznym

    Directory of Open Access Journals (Sweden)

    R. Dańko

    2012-12-01

    Full Text Available W publikacji przedstawiono uzupełniające metody badań oraz aparaturę do oceny jakości regeneratu i tych właściwości masformierskich ze spoiwami utwardzanymi chemicznie, przygotowywanych z regeneratem, które są istotne dla kompleksowej oceny procesurecyklingu osnowy. Nowoczesne systemy oceny mas formierskich wymagają bardziej wnikliwego podejścia do czynników decydującychzarówno o ich przydatności technologicznej jak również o wpływie na otaczające środowisko naturalne. W tym kontekście pełna ocenajakości zregenerowanej osnowy wykracza poza zwyczajowo stosowane metody instrumentalne i wymaga ich uzupełnienia o bardziejzaawansowane aparaturowo metody badawcze. Pozwala to szerzej spojrzeć na ocenę zregenerowanej osnowy, zarówno w aspekcie jejużycia do sporządzania mas formierskich, jako substytutu świeżego piasku, ale także pod kątem ochrony środowiska. Do takichnowoczesnych metod można zaliczyć między innymi analizę ziarnową regeneratu za pomocą dyfrakcji laserowej, a także ocenęgazotwórczości masy formierskiej oraz identyfikację rodzaju emitowanych gazów i zawartości w nich gazów z grupy BTEX, które sąszczególnie niebezpieczne z punktu widzenia BHP.

  17. Role of Mas receptor in renal blood flow response to angiotensin-(1-7) in ovariectomized estradiol treated rats.

    Science.gov (United States)

    Saberi, Shadan; Dehghani, Aghdas; Nematbakhsh, Mehdi

    2016-01-01

    The angiotensin 1-7 (Ang 1-7), is abundantly produced in kidneys and antagonizes the function of angiotensin II through Mas receptor (MasR) or other unknown mechanisms. In the current study, the role of MasR and steroid hormone estrogen on renal blood flow response to Ang 1-7 administration was investigated in ovariectomized (OV) female rats. OV female Wistar-rats received estradiol (500 μg/kg/week) or vehicle for two weeks. In the day of the experiment, the animals were anesthetized, cannulated, and the responses including mean arterial pressure, renal blood flow (RBF), and renal vascular resistance at the constant level of renal perfusion pressure to graded infusion of Ang 1-7 at 0, 100 and 300 ng/kg/min were determined in OV and OV estradiol-treated (OVE) rats, treated with vehicle or MasR antagonist; A779. RBF response to Ang 1-7 infusion increased dose-dependently in vehicle (Pdose <0.001) and A779-treated (Pdose <0.01) animals. However, when MasR was blocked, the RBF response to Ang 1-7 significantly increased in OV animals compared with OVE rats (P<0.05). When estradiol was limited by ovariectomy, A779 increased RBF response to Ang 1-7 administration, while this response was attenuated in OVE animals.

  18. Modified Ashworth Scale (MAS) Model based on Clinical Data Measurement towards Quantitative Evaluation of Upper Limb Spasticity

    Science.gov (United States)

    Puzi, A. Ahmad; Sidek, S. N.; Mat Rosly, H.; Daud, N.; Yusof, H. Md

    2017-11-01

    Spasticity is common symptom presented amongst people with sensorimotor disabilities. Imbalanced signals from the central nervous systems (CNS) which are composed of the brain and spinal cord to the muscles ultimately leading to the injury and death of motor neurons. In clinical practice, the therapist assesses muscle spasticity using a standard assessment tool like Modified Ashworth Scale (MAS), Modified Tardiue Scale (MTS) or Fugl-Meyer Assessment (FMA). This is done subjectively based on the experience and perception of the therapist subjected to the patient fatigue level and body posture. However, the inconsistency in the assessment is prevalent and could affect the efficacy of the rehabilitation process. Thus, the aim of this paper is to describe the methodology of data collection and the quantitative model of MAS developed to satisfy its description. Two subjects with MAS of 2 and 3 spasticity levels were involved in the clinical data measurement. Their level of spasticity was verified by expert therapist using current practice. Data collection was established using mechanical system equipped with data acquisition system and LABVIEW software. The procedure engaged repeated series of flexion of the affected arm that was moved against the platform using a lever mechanism and performed by the therapist. The data was then analyzed to investigate the characteristics of spasticity signal in correspondence to the MAS description. Experimental results revealed that the methodology used to quantify spasticity satisfied the MAS tool requirement according to the description. Therefore, the result is crucial and useful towards the development of formal spasticity quantification model.

  19. X-ray fluorescent analysis on Indo-Pacific glass beads from Sungai Mas archaeological sites, Kedah, Malaysia

    International Nuclear Information System (INIS)

    Zuliskandar Ramli; Nik Hassan Shuhaimi; Nik Abdul Rahman; Abdul Latif Samian

    2011-01-01

    Sungai Mas was an ancient port-kingdom located on West Coast of Peninsula Malaysia in a district of Kota Kuala Muda, Kedah, Malaysia. The port-kingdom evolved as an entrepot since fifth century AD and continuously visited by international trader from India, China, Middle East and Europe until eighteenth century AD. Sungai Mas was also one of the Indo-Pacific beads making centers in Southeast Asia since sixth to thirteenth century AD and also produced pottery and brick. X-ray fluorescent analysis (XRF) on Sungai Mas Indo-Pacific beads is carried out to determine whether the glass beads originated from Arikamedu, India or locally made by community in Sungai Mas. Totally, twenty-two samples of beads and beads materials assayed by XRF were chosen. Contents of nine major elements and nine trace elements, which might be present of flux, stabilizer, colorants or opacifier were examined. The elements Si, Na, K, Ca, Fe, Al, Ti, Mn, Mg, Cu, Pb, Zr, Sr, Ba, La, U, Ni and Cr were detectable in all samples. The concentration of elements found are discussed in terms of flux, silica or lead base glass, color and/or opacity of the glass beads and glass samples. The result showed that Sungai Mas produced their own Indo-Pacific beads from sixth to thirteenth century AD. (author)

  20. The demands and benefits of ergonomics in Sri Lankan apparel industry: A case study at MAS holdings.

    Science.gov (United States)

    Abeysekera, John; Illankoon, Prasanna

    2016-10-17

    Apparel exports bring in sizeable foreign income to Sri Lanka. To protect and promote this industry is a paramount need. This can be carried out by applying Human Factors/Ergonomics (HFE) which has proved to control negative effects at work places. This paper reports a case study which describes the demands and benefits of HFE in MAS Holdings which owns a large share of the apparel industry in Sri Lanka. The study consisted of walk through observation survey, a questionnaire survey and ergonomic work place analysis followed by a training programme to selected employees in three companies. Positive responses to questionnaires revealed good ergonomic practices in the work places surveyed. Ergonomically unfit chairs and potential hazards e.g. exposure to noise and hot environment were detected. It is seen that MAS have introduced strategies originated by Toyota Production System viz. 5S, Kaizen, six sigma etc., which are in fact ergonomic methods. A progressive project MAS boast of viz. 'MAS Operating System' (MOS) empowers training and development to employees. MAS Holdings has adequately realized the benefits of applying HFE as evident by the number of awards received. Relevant companies were advised to take appropriate corrective measures to control the potential hazards.

  1. Comparison of radiographic technique by computer simulation

    International Nuclear Information System (INIS)

    Brochi, M.A.C.; Ghilardi Neto, T.

    1989-01-01

    A computational algorithm to compare radiographic techniques (KVp, mAs and filters) is developed based in the fixation of parameters that defines the images, such as optical density and constrast. Before the experience, the results were used in a radiography of thorax. (author) [pt

  2. Aqueous U(VI) interaction with magnetite nanoparticles in a mixed flow reactor system: HR-XANES study

    International Nuclear Information System (INIS)

    Pidchenko, I; Heberling, F; Finck, N; Schild, D; Bohnert, E; Schäfer, T; Rothe, J; Geckeis, H; Vitova, T; Kvashnina, KO

    2016-01-01

    The redox variations and changes in local atomic environment of uranium (U) interacted with the magnetite nanoparticles were studied in a proof of principle experiment by the U L 3 and M 4 edges high energy resolution X-ray absorption near edge structure (HR-XANES) technique. We designed and applied a mixed flow reactor (MFR) set-up to maintain dynamic flow conditions during U-magnetite interactions. Formation of hydrolyzed, bi- and poly-nuclear U species were excluded by slow continuous injection of U(VI) (10 -6 M) and pH control integrated in the MFR set-up. The applied U HR-XANES technique is more sensitive to minor changes in the U redox states and bonding compared to the conventional XANES method. Major U(VI) contribution in uranyl type of bonding is found in the magnetite nanoparticles after three days operation time of the MFR. Indications for shortening of the U-O axial bond length for the magnetite compared to the maghemite system are present too. (paper)

  3. The effect of FF-MAS on porcine cumulus-oocyte complex maturation, fertilization and pronucleus formation in vitro

    DEFF Research Database (Denmark)

    Færge, Inger; Strejcek, Frantisek; Laurincik, Jozef

    2006-01-01

    mechanically using a fine glass pipette under constant pH and in vitro fertilized with fresh semen (5 x 105 spermatozoa/ml). The presumptive zygotes were evaluated 18 h after fertilization. The addition of pFF increased the monospermic as well as the polyspermic penetration of oocytes. In the absence of p......FF, the addition of FF-MAS decreased the polyspermic penetration rate, wehreas FF-MAS in combination with pFF decreased monospermic and increased polyspermic penetration. The degeneration rate of ova decreased in the presence of FF-MAS irrespective of the presence or absence of pFF. In the absence of pFF, FF...

  4. 1H line width dependence on MAS speed in solid state NMR - Comparison of experiment and simulation

    Science.gov (United States)

    Sternberg, Ulrich; Witter, Raiker; Kuprov, Ilya; Lamley, Jonathan M.; Oss, Andres; Lewandowski, Józef R.; Samoson, Ago

    2018-06-01

    Recent developments in magic angle spinning (MAS) technology permit spinning frequencies of ≥100 kHz. We examine the effect of such fast MAS rates upon nuclear magnetic resonance proton line widths in the multi-spin system of β-Asp-Ala crystal. We perform powder pattern simulations employing Fokker-Plank approach with periodic boundary conditions and 1H-chemical shift tensors calculated using the bond polarization theory. The theoretical predictions mirror well the experimental results. Both approaches demonstrate that homogeneous broadening has a linear-quadratic dependency on the inverse of the MAS spinning frequency and that, at the faster end of the spinning frequencies, the residual spectral line broadening becomes dominated by chemical shift distributions and susceptibility effects even for crystalline systems.

  5. Elimination of C3 as the Bond-Neff depression opacity source in Hr 774

    International Nuclear Information System (INIS)

    Baird, S.R.

    1982-01-01

    The pseudocontinuum of C 3 has been proposed by Fix as the source of the Bond-Neff depression in HR 774. In such a case the strongest rotational lines of the 4050 A vibrational band of C 3 should be clearly evident at high dispersion. A 2.2 A mm -1 plate of HR 774 is examined in the 4050--4060 A region where the strongest lines should form. The absence of C 3 rotational lines indicates that C 3 cannot be the major contributor to the Bond-Neff depression in HR 774

  6. Relation Between Acid and Catalytic Properties of Chlorinated Gamma-Alumina. a 31p Mas Nmr and Ftir Investigation

    Directory of Open Access Journals (Sweden)

    Guillaume D.

    1999-07-01

    Full Text Available In this paper, we have studied the effect of chlorine on the surface properties of gamma-alumina, especially on their acid properties. The use of FTIR spectroscopy and 31P MAS NMR of adsorbed trimethylphosphine allows to propose a chlorination mechanism. To correlate the surface properties of these chlorinated gamma-alumina with their catalytic properties, we have used a model reaction, the cracking of n-heptane under reforming conditions. The analysis of the correlation between acid properties determined by 31P MAS NMR and the catalytic results (in terms of activities and selectivities allows to identify which sites are involved in the cracking reaction.

  7. Decision-making support system based on MAS for emergency response to nuclear accidents of marine pressurized-water reactor

    International Nuclear Information System (INIS)

    Chen Dengke; Zhang Dafa; Jiang Wei; Chen Yonghong

    2007-01-01

    Emergency decision-making to Marine Pressurized-Water Reactor (MPWR) was severely restricted by the complex environment. To enhance the emergency decision-making ability of MPWR, reducing the effect of emergencies, an emergency Decision-making Support System (DSS) which based on Multi-agent System (MAS) was presented. In the system, the HLA/RTI was used as the support environment, and the structure and the Control Agent (SCA), Analyse Agent (AA), Countermeasure Agent (CA), Evaluation Agent (EVA) and Environment Agent (ENA) were designed. The MAS were with the characteristics of autonomy, reactivity and initiative, which were fully used in the system to make effective decision for emergencies. (authors)

  8. National Hydrography Dataset Plus High Resolution (NHDPlus HR) - USGS National Map Downloadable Data Collection

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The High Resolution National Hydrography Dataset Plus (NHDPlus HR) is an integrated set of geospatial data layers, including the best available National Hydrography...

  9. Status of SiO2/TiO2 HR coating damage

    International Nuclear Information System (INIS)

    Lowermilk, W.H.

    1979-01-01

    The data, observations, and conclusions from a number of experiments on high-reflector (HR) coating damage which were done in FY 1979 are summarized. Damage threshold measurements for the experiments described are presented

  10. The efficiency of SAP in improving the HR performance case study ...

    African Journals Online (AJOL)

    The efficiency of SAP in improving the HR performance case study: Masdar ... administrative and strategic levels, as well as identifying the contribution of ... Keywords: SAP, human resources management, Masdar Building Materials Company ...

  11. Intelligence and Information-Sharing Elements of S.4 and H.R. 1

    National Research Council Canada - National Science Library

    Masse, Todd

    2007-01-01

    Title I of S.4 and Title VII of H.R. 1 include corresponding measures related to enhancing information and intelligence sharing, both horizontally within the Federal Government and vertically between the Federal Government and state...

  12. Autolīzinga kompānijas AS "mogo" reklāmas kampaņu izstrāde, izmantojot Facebook reklāmas rīkus

    OpenAIRE

    Ābeltiņš, Elvis

    2017-01-01

    Diplomdarba tēma ir “Autolīzinga kompānijas AS “mogo” reklāmas kampaņu izstrāde, izmantojot Facebook reklāmas rīkus”. Vadošais sociālais tīkls Facebook nodrošina plašas reklāmas izvietošanas iespējas un tā auditorijas apjoms ir sasniedzis tradicionālajiem medijiem līdzvērtīgu izmēru. Darba analītiskajā daļā tiek kategorizētas digitālā mārketinga metodes, kā arī apkopota sociālo tīklu lietotāju statistika Latvijā un pasaulē. Projekta daļā autors salīdzina un analizē Facebook reklāmas izvietoša...

  13. Proton chemical shift tensors determined by 3D ultrafast MAS double-quantum NMR spectroscopy

    International Nuclear Information System (INIS)

    Zhang, Rongchun; Mroue, Kamal H.; Ramamoorthy, Ayyalusamy

    2015-01-01

    Proton NMR spectroscopy in the solid state has recently attracted much attention owing to the significant enhancement in spectral resolution afforded by the remarkable advances in ultrafast magic angle spinning (MAS) capabilities. In particular, proton chemical shift anisotropy (CSA) has become an important tool for obtaining specific insights into inter/intra-molecular hydrogen bonding. However, even at the highest currently feasible spinning frequencies (110–120 kHz), 1 H MAS NMR spectra of rigid solids still suffer from poor resolution and severe peak overlap caused by the strong 1 H– 1 H homonuclear dipolar couplings and narrow 1 H chemical shift (CS) ranges, which render it difficult to determine the CSA of specific proton sites in the standard CSA/single-quantum (SQ) chemical shift correlation experiment. Herein, we propose a three-dimensional (3D) 1 H double-quantum (DQ) chemical shift/CSA/SQ chemical shift correlation experiment to extract the CS tensors of proton sites whose signals are not well resolved along the single-quantum chemical shift dimension. As extracted from the 3D spectrum, the F1/F3 (DQ/SQ) projection provides valuable information about 1 H– 1 H proximities, which might also reveal the hydrogen-bonding connectivities. In addition, the F2/F3 (CSA/SQ) correlation spectrum, which is similar to the regular 2D CSA/SQ correlation experiment, yields chemical shift anisotropic line shapes at different isotropic chemical shifts. More importantly, since the F2/F1 (CSA/DQ) spectrum correlates the CSA with the DQ signal induced by two neighboring proton sites, the CSA spectrum sliced at a specific DQ chemical shift position contains the CSA information of two neighboring spins indicated by the DQ chemical shift. If these two spins have different CS tensors, both tensors can be extracted by numerical fitting. We believe that this robust and elegant single-channel proton-based 3D experiment provides useful atomistic-level structural and dynamical

  14. Microturbulence as a third dimension in the G-K giant region of the HR diagram

    International Nuclear Information System (INIS)

    Foy, R.

    1978-01-01

    The structure of the HR diagram in the G-K giant region is complex, because of the funneling effect and of the intersection of evolutionary tracks for different stellar masses. Therefore it is impossible to derive the age of a cool giant from its location in the HR diagram alone. To remove this indeterminacy a third dimension is needed, and the author suggests microturbulence as the appropriate observational parameter. (Auth.)

  15. EXCEPTIONAL CLOSURE OF VARIOUS HR DEPARTEMENT SERVICES ON 20 AND 21 SEPTEMBER 2007

    CERN Document Server

    HR Department

    2007-01-01

    Due to a group training event, the following services will be exceptionally closed on Thursday 20 and Friday 21 September 2007 : installation service (removals, cars, diplomatic privileges), school fees, Personnel Records Office (including attestations), French visas; duty travel, leave, reinstallation indemnity, unemployment benefit, tax information and social affairs. The French and Swiss cards service will remain open as usual, from 8:30 to 12:30. Thank you for your understanding. HR Department HR-SPS Group

  16. EXCEPTIONAL CLOSURE OF VARIOUS HR DEPARTMENT SERVICES ON 20 AND 21 SEPTEMBER 2007

    CERN Document Server

    *Beyond was established as CIC Productions to produce the television series Beyond 2000 for the Seven Network in Australia,

    2007-01-01

    Due to a group training event, the following services will be exceptionally closed on Thursday 20 and Friday 21 September 2007: installation service (removals, cars, diplomatic privileges), school fees, Personnel Records Office (including attestations), French visas; duty travel, leave, reinstallation indemnity, unemployment benefit, tax information and social affairs. The French and Swiss cards service will remain open as usual, from 8:30 to 12:30. Thank you for your understanding. HR Department HR-SPS Group

  17. A Role For HR In Corporate Ethics? South African Practitioners’ Perspectives

    OpenAIRE

    L. J. van Vuuren; R. J. Eiselen

    2006-01-01

    Since few South African organisations have as yet appointed ethics officers, there is often a lack of clarity on who should take responsibility for coordinating organisations’ ethics management efforts. The purpose of this paper was to assess HR (the Human Resource function and its practitioners) as a possible contender to assume responsibility for ethics management in SA organisations. To this end a mail survey was conducted among registered HR practitioners (N=410). Two factors related to 1...

  18. Acute effects of Cu on oxygen consumption and 96 hr-LC 50 values ...

    African Journals Online (AJOL)

    The median lethal copper (Cu) concentration (96 hr-LC50) values for acute Cu toxicity for Tilapia sparrmanii (live mass: 30 ± 8g) in Mooi River hard water of dolomitic origin at 20° C, pH 7.9, was 68.1 µmol l–1. At this 96 hr-LC50 value the specific oxygen consumption rate (∉ O2) decreased by 44.2 (± 2.1) % from a ...

  19. Synthetic H-R diagrams as an observational test of stellar evolution theory

    International Nuclear Information System (INIS)

    Mathews, G.J.; Becker, S.A.; Brunish, W.M.

    1983-07-01

    Synthetic H-R diagrams are constructed from a grid of stellar models. These are compared directly with observations of young clusters in the LMC and SMC as a test of the models and as a means to determine the age, age dispersion, and composition of the clusters. Significant discrepancies between the observed and model H-R diagrams indicate the possible influences of convective overshoot, large AGB mass-loss rates, and the best value for the mixing length parameter

  20. Doctor-patient relationships (DPR) in China: managers and clinicians’ twofold pathways from commitment HR practices

    OpenAIRE

    Ma, S.; Xu, X.; Trigo, V.; Ramalho, N. J. C.

    2017-01-01

    Purpose: The first objective of this research is to develop and test theory on how commitment human resource (HR) practices affect hospital professionals’ job satisfaction that motivates them to generate desirable patient care and subsequently improve doctor-patient relationships (DPR). The second objective is to examine how commitment HR practices influence in different ways hospital managers and clinicians. Methodology: Using a cross-sectional survey, data were collect from 508 clinicians a...

  1. Discussion on the fusing methods for HR and CCD images of CBERS

    International Nuclear Information System (INIS)

    Gao Zhangsheng; Zhao Yingjun

    2010-01-01

    CBERS-02B multi-spectral CCD data are different from HR panchromatic data in resolution, which causes difficulty in image fusion. With the method of Pansharping, HPF, Brovey transform, IHS transform, principal component transform, Gram Schmidt (GS) transform and wavelet transform, the authors have tested the fusion methods for CCD data and HR data of CBERS, and the fusion results are discussed and evaluated qualitatively and quantitatively. (authors)

  2. Site specific health and safety plan, 100-HR-3 pump and treat. Revision 1

    International Nuclear Information System (INIS)

    Tuttle, B.G.

    1996-06-01

    The 100-HR-3 Operable Unit encompasses groundwater contamination underlying the 100-D and 100-H Areas. The primary contaminate is chromium VI. The sources of chromium contamination resulted from the use of sodium dichromate during past reactor operations. The purpose of the 100-HR-3 Pump-and-Treat system is to pump contaminated groundwater through aboveground ion exchange resin and then return the treated waster to the aquifer. This plan covers operation, maintenance, repairs, and pump removal/installation

  3. I-123 IBZM-SPECT: improved acquisition protocol with HR-collimator

    International Nuclear Information System (INIS)

    Sandrock, D.; Ivancevic, V.; Dopichaj-Menge, U.; Gruber, D.; Munz, D.

    2002-01-01

    Aim: Aim of this study was to evaluate the impact of different acquisition and reconstruction protocols on the quality of SPECT diagnostics with I-123 IBZM in patients with diseases of the dopaminergic system. Material and Methods: Overall, 30 patients (19 men, 11 women, aged 22 - 80 years) were studied with SPECT after i.v. injection of 5 mCi (185 MBq) I-123 IBZM. Acquisition was performed 60 min p.i. (protocol A) using a medium energy collimator, a 64 x 64 matrix, 64 projections, step and shoot technique, 5.6 0 and 20 seconds per step with a MultiSPECT2 double-head gamma camera (Siemens). Immediately afterwards, a second acquisition (protocol B, 90 min p.i.) using a high resolution collimator, a 128 x 128 matrix, 60 projections, step and shoot technique, 3 0 and 30 seconds per step was performed. The reconstruction was done in filtered backprojection technique and a Butterworth filter of order 7, in protocol A using a cutoff of 0.5 and in protocol B of 0.4. Finally, the net count ratios of the basal ganglia to the frontal lobe(s) were calculated and compared with the clinical diagnosis. Results: The visual analysis yielded - as expected -a better image quality for protocol B (concordant impression of 3 independent observers) with more accurate delineation of the basal ganglia. The count ratios with protocol B were (mean) 0.19 higher (equivalent to 13 %) than with protocol A. In the group of patients with count ratios > 1.55 there was the highest (and significant) difference between protocols A and B with (mean count ratio difference) 0.32 (equivalent to 20 %). Protocol B also allowed a better differentiation between patients clinically staged normal and abnormal. In patients with unilateral disease, this difference between normal and abnormal was more prominent (in comparison to the contralateral side as well as compared to the reference value [1.5]). The comparison of the count ratios with the clinical data revealed 7 patients with borderline results with

  4. Can Memory Assessment Services (MAS) in England be categorized? A national survey.

    Science.gov (United States)

    Chrysanthaki, T; Fernandes, B; Smith, S; Black, N

    2017-12-01

    The effectiveness and efficiency of memory assessment services (MASs) is unknown. Our aim was to determine if a typology can be constructed, based on shared structural and process characteristics, as a basis for a non-randomized evaluation of their effectiveness and cost-effectiveness. Survey of random sample of 73 MASs in 2015; comparison of characteristics and investigation of inter-correlation. It was not possible to group characteristics to form the basis of a typology of MASs. However, there was considerable variation in staff numbers (20-fold), new patients per whole-time equivalent (WTE) staff (20-fold), skill mix and the nurse:doctor ratio (1-10). The operational performance also varied: first appointments (50-120 minutes); time for first follow-up (2-12 weeks); frequency of follow-up in first year (1-5). These differences were not associated with the number of new patients per WTE staff or the accreditation status of the MAS. Post diagnosis, all MASs provided pharmacological treatment but the availability of non-pharmacological support varied, with half providing none or only one intervention while others providing four or more. In the absence of any clear typology, evaluation of MASs will need to focus on the impact of individual structural and process characteristics on outcomes. © The Author 2017. Published by Oxford University Press on behalf of Faculty of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

  5. MAS Based Distributed Automatic Generation Control for Cyber-Physical Microgrid System

    Institute of Scientific and Technical Information of China (English)

    Zhongwen Li; Chuanzhi Zang; Peng Zeng; Haibin Yu; Hepeng Li

    2016-01-01

    The microgrid is a typical cyber-physical microgrid system(CPMS). The physical unconventional distributed generators(DGs) are intermittent and inverter-interfaced which makes them very different to control. The cyber components,such as the embedded computer and communication network,are equipped with DGs, to process and transmit the necessary information for the controllers. In order to ensure system-wide observability, controllability and stabilization for the microgrid,the cyber and physical component need to be integrated. For the physical component of CPMS, the droop-control method is popular as it can be applied in both modes of operation to improve the grid transient performance. Traditional droop control methods have the drawback of the inherent trade-off between power sharing and voltage and frequency regulation. In this paper, the global information(such as the average voltage and the output active power of the microgrid and so on) are acquired distributedly based on multi-agent system(MAS). Based on the global information from cyber components of CPMS, automatic generation control(AGC) and automatic voltage control(AVC)are proposed to deal with the drawback of traditional droop control. Simulation studies in PSCAD demonstrate the effectiveness of the proposed control methods.

  6. MAS Based Distributed Automatic Generation Control for Cyber-Physical Microgrid System

    Institute of Scientific and Technical Information of China (English)

    Zhongwen Li; Chuanzhi Zang; Peng Zeng; Haibin Yu; Hepeng Li

    2016-01-01

    The microgrid is a typical cyber-physical micro grid system (CPMS).The physical unconventional distributed generators (DGs) are intermittent and inverter-interfaced which makes them very different to control.The cyber components,such as the embedded computer and communication network,are equipped with DGs,to process and transmit the necessary information for the controllers.In order to ensure system-wide observability,controllability and stabilization for the microgrid,the cyber and physical component need to be integrated.For the physical component of CPMS,the droop-control method is popular as it can be applied in both modes of operation to improve the grid transient performance.Traditional droop control methods have the drawback of the inherent trade-off between power sharing and voltage and frequency regulation.In this paper,the global information (such as the average voltage and the output active power of the microgrid and so on) are acquired distributedly based on multi-agent system (MAS).Based on the global information from cyber components of CPMS,automatic generation control (AGC) and automatic voltage control (AVC) are proposed to deal with the drawback of traditional droop control.Simulation studies in PSCAD demonstrate the effectiveness of the proposed control methods.

  7. Healthcare benefits linked with Below Poverty Line registration in India: Observations from Maharashtra Anaemia Study (MAS).

    Science.gov (United States)

    Ahankari, Anand; Fogarty, Andrew; Tata, Laila; Myles, Puja

    2017-01-01

    A 2015 Lancet paper by Patel et al. on healthcare access in India comprehensively discussed national health programmes where some benefits are linked with the country's Below Poverty Line (BPL) registration scheme. BPL registration aims to support poor families by providing free/subsidised healthcare. Technical issues in obtaining BPL registration by poor families have been previously reported in the Indian literature; however there are no data on family assets of BPL registrants. Here, we provide evidence of family-level assets among BPL registration holders (and non-BPL households) using original research data from the Maharashtra Anaemia Study (MAS). Social and health data from 287 pregnant women and 891 adolescent girls (representing 1178 family households) across 34 villages in Maharashtra state, India, were analysed. Several assets were shown to be similarly distributed between BPL and non-BPL households; a large proportion of families who would probably be eligible were not registered, whereas BPL-registered families often had significant assets that should not make them eligible. This is likely to be the first published evidence where asset distribution such as agricultural land, housing structures and livestock are compared between BPL and non-BPL households in a rural population. These findings may help planning BPL administration to allocate health benefits equitably, which is an integral part of national health programmes.

  8. Quality Analysis of Ceramic Tent Product With Six Sigma Method in PT. Mas Keramik KIA

    Science.gov (United States)

    Suryadi, A.; Ardiansyah P., F.; Ngatilah, Y.

    2018-01-01

    PT. KIA Keramik Mas is a company engaged in manufacturing, which produces ceramic tiles, one of the problems faced by this company is the number of defects found, in the July - December 2015 amounted to 6,259,945 units producing tiles and discovered defects by 960 683 units with an object research is ceramic tile products, among some of the defects found several characteristics of defects that occur include rugged body, coincide, grainy, scratched, and colors distorted. The purpose of this study was to determine the quality of the product and propose improvements that reduce the number of such defects, using quality control methods that Six Sigma. Six Sigma is used to generate a defect that does not exceed 3.4 DPMO (defects per million opportunities) or zero defect which is an approach to calculate the number of defects per million possibilities. Average quality ceramic tile products during the month of July - December 2015 was on a sigma of 3.37 with DPMO of 30 586, which means that one million opportunities that exist there will be 30 586 (3,05%) the possibility that the process of making the ceramic tile defect or defects occur, so to get to the required target of Six Sigma improvement.

  9. Nutritional value of Rosa spp. l. and Cornus mas l. fruits, as affected by storage conditions

    Directory of Open Access Journals (Sweden)

    Craita-Maria Rosu

    2011-12-01

    Full Text Available A comparison between two storage methods (freezing and drying of fruits, in terms of ascorbic acid, carotenes, total sugar and protein content in Rosa spp. L. species and Cornus mas L. was performed. In the dried rose hips, the major losses were registered at the level of ascorbic acid content (32.04–50.25 %, followed by carotenes (30.85–52.08 %, total sugar (21.57–34.6 % and protein content (21.33–46.89 %. The freezing method resulted in a better preservation of ascorbic acid (only 19.80–29.21 % decrease and total sugar content (3.41–12.94 % increase. In the preserved cornelian cherry fruits, no statistically significant differences were registered between fruits categories, except carotene content, which was dramatically decreased in dried fruits (88.23 %. For cornelian cherry fruits, both storage methods induced a decrease of ascorbic acid and protein contents (57.60 and 46.32 % and an increase of total sugar level (37.60 %.

  10. Tendencias clave para el tercer gobierno del MAS, Bolivia 2015-2019

    Directory of Open Access Journals (Sweden)

    Xavier Albó

    2016-03-01

    Esta presentación tiene como trasfondo el Plan Nacional de Desarrollo y pretende resaltar algunos de los logros del presidente Evo Morales y los desafíos que enfrenta en su tercer gobierno (2015-2019. Comienza revisando información demográfica básica, según el Censo de 2012, para luego centrarse en la economía: los hidrocarburos, la minería, la producción agropecuaria y la ecología. El boom de la quinua, la expansión de la frontera agrícola y la suspensión de la construcción de una carretera que atraviese el TIPNIS son algunos de los temas que se discuten. Internacionalmente, hay motivos de optimismo con relación a la demanda marítima de Bolivia, mientras que, a nivel nacional, el MAS aseguró una victoria parlamentaria en el año 2014. Las reformas menos exitosas son las del órgano judicial. La presentación termina revisando los movimientos sociales que permitieron la formación la de Asamblea Constituyente y el asunto de la autonomía municipal, departamental e indígena.

  11. Characterization of coal structure by CP/MAS carbon-13 NMR spectrometry

    International Nuclear Information System (INIS)

    Yoshida, T.; Maekawa, Y.

    1987-01-01

    Cross-polarization (CP)/magic angle spinning (MAS) carbon-13 nuclear magnetic resonance (n.m.r.) spectrometry has been applied to the analysis of the whole structures of different ranks of coal. Three basic structural parameters, namely carbon aromaticity fa, new carbon aromaticity fa', and atomic H/C ratio for the hypothetical unsubstituted aromatic nuclei Haru/Car, were derived from the combined data of ultimate analysis, the distributions of carbon and oxygen functional groups obtained from the spectrum and the distribution of four types of methylene carbon groups in coal. Both fa and fa' values generally increased with coal rank and ranged from 0.51 to 0.71 and from 0.62 to 0.76, respectively. Haru/Car value tended to decrease with coal rank although the value was greatly affected by the types of hydroaromatic methylene carbons to aromatic rings. The values indicated that lower-rank coals consisted mainly of 1-3 aromatic rings, and higher-rank coals, 3-5 aromatic rings. 24 refs.; 5 figs.; 4 tabs

  12. The Neuroprotective Effect of Cornus mas on Brain Tissue of Wistar Rats

    Directory of Open Access Journals (Sweden)

    Renata Francik

    2014-01-01

    Full Text Available Cornelian cherry (Cornus mas is a valuable source of phenolic antioxidants. Flavonoid derivatives as nonenzymatic antioxidants are important in the pathophysiology of many diseases including neurological disorders (e.g., Alzheimer’s disease or heart disease. In this study, we examined the effect of an addition of freeze-dried fruit of cornelian cherry on three types of diets: control diet, fructose diet, and diet enriched in fats (high-fat diet. This effect was studied by determining the following antioxidant parameters in both brain tissue and plasma in rats: catalase, ferric reducing ability of plasma, paraoxonase, protein carbonyl groups, and free thiol groups. Results indicate that both fructose diet and high-fat diet affect the antioxidant capacity of the organism. Furthermore, an addition of cornelian cherry resulted in increased activity of catalase in brain tissue, while in plasma it caused the opposite effect. In turn, with regard to paraoxonase activity in both brain tissue and plasma, it had a stimulating effect. Adding cornelian cherry to the tested diets increased the activity of PON in both tested tissues. Moreover, protective effect of fruits of this plant was observed in the process of oxidation of proteins by decreasing levels of protein carbonyl groups and thiol groups in brain tissue as well as in plasma.

  13. CINEMA E LITERATURA: mediações em “Bonitinha, mas ordinária”

    Directory of Open Access Journals (Sweden)

    Elen Duarte MIRANDA e SILVA

    2011-01-01

    Full Text Available A partir de um intenso movimento de metamorfoses técnicas e narrativas, o cinema passou de seu estado inicial de mero copiador da realidade à categoria de arte e vem estabelecendo uma forte e íntima relação de diálogo com a literatura. É a partir dessa relação que o destaque dessa pesquisa consiste em uma análise sobre a literatura dramatúrgica de Nelson Rodrigues e sua respectiva adaptação pelo cinema de Braz Chediak, com ênfase no trabalho em parceria entre escritor e cineasta:Bonitinha, mas ordinária: até que ponto o filme se subordina ao texto? Há inventividade na inscrição cinematográfica de Braz? Qual o teor criativo da narrativa do cineasta? Em que instância o filme foi produzido? Qual a tendência estética adotada pelo diretor? Essas questões são desvendadas através da colaboração teórica de Roland Barthes, Ismail Xavier, Sábato Malgadi e Robert Stam, bem como alguns outros estudiosos que pensam cinema e literatura e entram em cena para adensarem a análise feita sobre o objeto colocado em foco.

  14. Characterization of cornelian cherry (Cornus mas L. genotypes - genetic resources for food production in Czech Republic

    Directory of Open Access Journals (Sweden)

    Sochor Jiri

    2014-01-01

    Full Text Available The aim of the study was to determine and compare both technological properties and polyphenol content in fruits of eight cornellian cherry (Cornus mas L. cultivars from Czech Republic. The fruits of cultivar ´Vydubeckij´ had the highest dry matter (17.4% and soluble solid (15.8% content among searched cultivars. The highest crude protein and phosphorus values were determined in the fruits of the ´Titus´ cultivar as 10.9 g of crude protein and 435 mg of phosphorus for per kg fresh weight (FW base. The ´Elegantnyj´ and ´Vydubeckij´ cultivars are found to be more suitable for canning industry. The fruits of the ´Vydubeckij´ cultivar contained 10.8 g of pectin and 22.4 g of citric acid per kg fresh weight base, and could be important for technological use because of their excellent gelling ability. ´Devin´,´Vydubeckij´ and ´Titus´ cultivars had the most valuable source of chlorogenic acid (135.6, 110.9 and 115.1 mg per 100 g FW, respectively and quercetin (24.9, 25.2 and 24.2 mg per 100 g FW, respectively. This work should contribute to the popularization of this fruit specie as a valuable source of technological parameters for human nutrition and the canning industry.

  15. Conformational analysis of capsaicin using 13C, 15N MAS NMR, GIAO DFT and GA calculations

    Science.gov (United States)

    Siudem, Paweł; Paradowska, Katarzyna; Bukowicki, Jarosław

    2017-10-01

    Capsaicin produced by plants from genus Capsicum exerts multiple pharmacological effects and has found applications in food and pharmaceutical industry. The alkaloid was studied by a combined approach: solid-state NMR, GA conformational search and GIAO DFT methods. The 13C CPMAS NMR spectra were recorded using variable contact time and dipolar dephasing experiments. The results of cross-polarization (CP) kinetics, such as TCP values and long T1ρH (100-200 ms), indicated that the capsaicin molecule is fairly mobile, especially at the end of the aliphatic chain. The15N MAS NMR spectrum showed one narrow signal at -255 ppm. Genetic algorithm (GA) search with multi modal optimization was used to find low-energy conformations of capsaicin. Theoretical GIAO DFT calculations were performed using different basis sets to characterize five selected conformations. 13C CPMAS NMR was used as a validation method and the experimental chemical shifts were compared with those calculated for selected stable conformers. Conformational analysis suggests that the side chain can be bent or extended. A comparison of the experimental and the calculated chemical shifts indicates that solid capsaicin does not have the same structure as those established by PWXRD.

  16. RECONNAISSANCE OF THE HR 8799 EXOSOLAR SYSTEM. I. NEAR-INFRARED SPECTROSCOPY

    Energy Technology Data Exchange (ETDEWEB)

    Oppenheimer, B. R.; Beichman, C.; Brenner, D.; Nilsson, R.; Parry, I. R.; Rice, E. [Astrophysics Department, American Museum of Natural History, Central Park West at 79th Street, New York, NY 10024 (United States); Baranec, C.; Dekany, R.; Hale, D. [Caltech Optical Observatories, California Institute of Technology, Pasadena, CA 91125 (United States); Burruss, R.; Cady, E.; Ligon, E. R.; Lockhart, T. [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Dr., Pasadena CA 91109 (United States); Crepp, J. R.; Hillenbrand, L.; Hinkley, S. [Department of Astronomy, California Institute of Technology, 1200 E. California Blvd, MC 249-17, Pasadena, CA 91125 (United States); Fergus, R. [Department of Computer Science, Courant Institute of Mathematical Sciences, New York University, 715 Broadway, New York, NY 10003 (United States); Hogg, David W. [Center for Cosmology and Particle Physics, Department of Physics, New York University, 4 Washington Place, New York, NY 10003 (United States); King, D. [Institute of Astronomy, Cambridge University, Madingley Road, Cambridge CB3 0HA (United Kingdom); Pueyo, L., E-mail: bro@amnh.org [Department of Physics and Astronomy, The Johns Hopkins University, Baltimore, MD 21218 (United States); and others

    2013-05-01

    We obtained spectra in the wavelength range {lambda} = 995-1769 nm of all four known planets orbiting the star HR 8799. Using the suite of instrumentation known as Project 1640 on the Palomar 5 m Hale Telescope, we acquired data at two epochs. This allowed for multiple imaging detections of the companions and multiple extractions of low-resolution (R {approx} 35) spectra. Data reduction employed two different methods of speckle suppression and spectrum extraction, both yielding results that agree. The spectra do not directly correspond to those of any known objects, although similarities with L and T dwarfs are present, as well as some characteristics similar to planets such as Saturn. We tentatively identify the presence of CH{sub 4} along with NH{sub 3} and/or C{sub 2}H{sub 2}, and possibly CO{sub 2} or HCN in varying amounts in each component of the system. Other studies suggested red colors for these faint companions, and our data confirm those observations. Cloudy models, based on previous photometric observations, may provide the best explanation for the new data presented here. Notable in our data is that these presumably co-eval objects of similar luminosity have significantly different spectra; the diversity of planets may be greater than previously thought. The techniques and methods employed in this paper represent a new capability to observe and rapidly characterize exoplanetary systems in a routine manner over a broad range of planet masses and separations. These are the first simultaneous spectroscopic observations of multiple planets in a planetary system other than our own.

  17. KERAGAAN PERTUMBUHAN BENIH IKAN MAS (Cyprinus carpio STRAIN MAJALAYA, LOKAL BOGOR DAN RAJADANU DI KOLAM CIJERUK, BOGOR-JAWA BARAT

    Directory of Open Access Journals (Sweden)

    Otong Zenal Arifin

    2016-11-01

    Full Text Available Penelitian ini bertujuan untuk mendapatkan strain ikan mas yang memiliki keragaan pertumbuhan yang baik sebagai spesies kandidat untuk program seleksi. Tiga strain ikan mas (majalaya, lokal Bogor, dan rajadanu dipelihara dalam jaring yang diletakkan di kolam Instalasi Penelitian Cijeruk, Bogor selama 6 minggu. Hasil penelitian menunjukkan bahwa tidak ada perbedaan nyata untuk parameter pertambahan bobot dan sintasan dari 3 strain ikan mas yang diuji, sedangkan untuk pertambahan panjang individual (mm per bulan ada perbedaan yang sangat nyata (P<0,05. Strain ikan mas rajadanu memiliki pertambahan panjang terbaik (16,0 ± 1,41 dan berbeda dengan majalaya (10,3 ± 4,50 serta lokal (10,8 ± 2,06. Objective of this study is to produce good performance of common carp by comparing three promising strains majalaya, local, and rajadanu. The study was carry out using floating net cages placed in earthen pond at The Cijeruk Germ Plasm Research Station. During the study, growth and survival rate were observed were observed for six weeks. The results indicated there was no significant difference for growth of weight and survival rate. However, growth of standard length was significantly different (P<0.05. Rajadanu made the best growth of standard length (16.0 ± 1.41 and was different from majalaya (10.3 ± 4.50 and local strain (10.8 ± 2.06.

  18. A preliminary study of the relation between adsorption and CP-MAS-NMR characteristics of fused silica model substrates

    NARCIS (Netherlands)

    Scholten, A.B.; Janssen, J.G.M.; Haan, de J.W.; Cramers, C.A.M.G.; Sandra, P.J.F.; Devos, G.; Sandra, P.

    1993-01-01

    The fumed silica model substrate Aerosil was trimethylsilylated to different extents and studied by the combination of IGC and 29Si CP-MAS-NMR. Dihydroxydisiloxane groups were shown to be chemically more reactive than monohydroxytrisiloxane groups. Chromatographic experiments showed that these

  19. Study on MAs transmutation of accelerator-driven system sodium-cooled fast reactor loaded with metallic fuel

    International Nuclear Information System (INIS)

    Han Song; Yang Yongwei

    2007-01-01

    Through the analysis of the effect of heavy metal actinides on the effective multiplication constant (k eff ) of the core in accelerator-driven system (ADS) sodium-cooled fast reactor loaded with metallic fuel, we gave the method for determining fuel components. the characteristics of minor actinides (MAs) transmutation was analyzed in detail. 3D burn-up code COUPLE, which couples MCNP4c3 and ORIGEN2, was applied to the neutron simulation and burn up calculation. The results of optimized scheme shows that adjusting the proportion of 239 Pu and maintaining the value during the burn-up cycle is an efficient method of designing k eff and keeping stable during the burn-up cycle. Spallation neutrons lead to the neutron spectrum harder at inner core than that at outer core. It is in favor of improving MA's fission cross sections and the capture-to-fission ratio. The total MAs transmutation support ratio 8.3 achieves excellent transmutation effect. For higher flux at inner core leads to obvious differences on transmutation efficiency,only disposing MAs at inner core is in favor of decreasing the loading mass and improving MAs transmutation effect. (authors)

  20. States' Participation Guidelines for Alternate Assessments Based on Modified Academic Achievement Standards (AA-MAS) in 2008. Synthesis Report 71

    Science.gov (United States)

    Lazarus, Sheryl S.; Rogers, Christopher; Cormier, Damien; Thurlow, Martha L.

    2008-01-01

    Federal regulations (U.S. Department of Education, 2007a) provide states with the flexibility to offer an alternate assessment based on modified academic achievement standards (AA-MAS). This assessment option is for a small group of students with disabilities who can make significant progress, but may not reach grade-level achievement within the…

  1. Improved quantification of alite and belite in anhydrous Portland cements by 29Si MAS NMR: Effects of paramagnetic ions

    DEFF Research Database (Denmark)

    Poulsen, Søren Lundsted; Kocaba, Vanessa; Le Saoût, Gwenn

    2009-01-01

    The applicability, reliability, and repeatability of 29Si MAS NMR for determination of the quantities of alite (Ca3SiO5) and belite (Ca2SiO4) in anhydrous Portland cement was investigated in detail for 11 commercial Portland cements and the results compared with phase quantifications based...

  2. EVALUASI DAYA TAHAN IKAN MAS HASIL SELEKSI BERDASARKAN MARKA MOLEKULER MHC-II TERHADAP INFEKSI KOI HERPES VIRUS

    Directory of Open Access Journals (Sweden)

    Erma Primanita Hayuningtyas

    2015-03-01

    mengevaluasi daya tahan benih ikan mas F-1 terseleksi terhadap infeksi KHV melalui uji tantang. Sebagai pembanding, digunakan ikan mas populasi benih F-1 non-seleksi dan populasi benih ikan mas dari unit pembenihan rakyat (UPR. Ikan uji berupa benih ikan mas Rajadanu berumur dua bulan dengan bobot ratarata 5,5±0,5 g. Jumlah benih pada masing-masing wadah perlakuan sebanyak 30 ekor dengan tiga kali pengulangan. Wadah pengujian berupa akuarium berukuran 40 cm x 60 cm x 40 cm dengan kepadatan 1 ekor/L. Parameter yang diamati adalah sintasan, deteksi KHV, analisis ekspresi gen MHC-II, dan gambaran darah ikan. Hasil penelitian menunjukkan bahwa populasi benih F-1 terseleksi memiliki daya tahan lebih baik dengan sintasan 93,33% dibandingkan populasi benih F-1 non-seleksi sebesar 85,55% dan populasi benih dari UPR sebesar 81,11%. Daya tahan yang tinggi pada populasi benih F-1 terseleksi didukung oleh hasil deteksi KHV yang negatif dan ersentase jumlah limfosit yang lebih tinggi sebesar 91,67%; serta rendahnya persentase monosit dan heterofil, selain itu, tidak adanya eosinofil dan basofil. Ekspresi gen MHC-II terdeteksi pada berbagai organ, ekspresi tertinggi ditemukan pada organ limpa.

  3. Angiotensin-converting enzyme 2, Angiotensin-(1-7) and Mas: new players of the Renin Angiotensin System

    DEFF Research Database (Denmark)

    Santos, Robson AS; Ferreira, Anderson J; Verano-Braga, Thiago

    2013-01-01

    /proliferative arm of the RAS consisting of ACE, Ang II and AT1 receptor. In this brief review, we will discuss recent findings related to the biological role of the ACE2/Ang-(1-7)/Mas arm in the cardiovascular and renal systems, as well as in metabolism. In addition, we will highlight the potential interactions...

  4. New perspectives of 19F MAS NMR in the characterization of amorphous forms of atorvastatin in dosage formulations

    Czech Academy of Sciences Publication Activity Database

    Brus, Jiří; Urbanová, Martina; Šeděnková, Ivana; Brusová, H.

    2011-01-01

    Roč. 409, 1/2 (2011), s. 62-74 ISSN 0378-5173 R&D Projects: GA MŠk 2B08021 Institutional research plan: CEZ:AV0Z40500505 Keywords : 19F MAS NMR * factor analysis * polymorphism Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 3.350, year: 2011

  5. {sup 1}H and {sup 23}Na MAS NMR spectroscopy of cationic species in CO{sub 2} selective alkaline earth metal porous silicoaluminophosphates prepared via liquid and solid state ion exchange

    Energy Technology Data Exchange (ETDEWEB)

    Arevalo-Hidalgo, Ana G. [Department of Chemical Engineering, University of Puerto Rico-Mayagueez Campus, Mayagueez, PR 00681-9000 (Puerto Rico); Dugar, Sneha; Fu, Riqiang [National High Magnetic Field Laboratory, Florida State University, Tallahassee, FL 32310 (United States); Hernandez-Maldonado, Arturo J., E-mail: arturoj.hernandez@upr.edu [Department of Chemical Engineering, University of Puerto Rico-Mayagueez Campus, Mayagueez, PR 00681-9000 (Puerto Rico)

    2012-07-15

    The location of extraframework cations in Sr{sup 2+} and Ba{sup 2+} ion-exchanged SAPO-34 was estimated by means of {sup 1}H and {sup 23}Na MAS NMR spectroscopy and spectral deconvolution. Incorporation of the alkaline earth metal cations onto the SAPO framework was achieved via liquid state ion exchange, coupled partial detemplation/solid-state ion exchange, and combination of both techniques. MAS NMR revealed that the level of ion exchange was limited by the presence of protons and sodium cations near hexagonal prisms (site SI), which are relatively difficult to exchange with the alkaline earth metal due to steric and charge repulsion criteria. In addition, the presence of ammonium cations in the supercages facilitated the exchange of otherwise tenacious hydrogen as corroborated by unit cell compositional data as well as enhanced CO{sub 2} adsorption at low partial pressures. The extraframework ammonium species were produced from partial detemplation of the structure-directing agent employed for the SAPO-34 synthesis, tetraethylammonium. - Graphical abstract: MAS NMR was used to elucidate the position the cationic species in alkaline earth metal exchanged silicoaluminophosphates. These species played a significant role during the ion exchange process and, therefore, the materials ultimate CO{sub 2} adsorption performance. Highlights: Black-Right-Pointing-Pointer Location of extraframework Sr{sup 2+} or Ba{sup 2+} cations was estimated by means of {sup 1}H and {sup 23}Na MAS NMR. Black-Right-Pointing-Pointer Level of Sr{sup 2+} or Ba{sup 2+} ion exchange was limited by the presence of protons and sodium cations. Black-Right-Pointing-Pointer Presence of ammonium cations in the supercages facilitated the exchange. Black-Right-Pointing-Pointer Sr{sup 2+} and Ba{sup 2+} ion exchanged SAPOs are outstanding CO{sub 2} adsorbents.

  6. HR 8844: A New Transition Object between the Am Stars and the HgMn Stars?

    Science.gov (United States)

    Monier, R.; Gebran, M.; Royer, F.; Kilicoglu, T.; Frémat, Y.

    2018-02-01

    While monitoring a sample of apparently slowly rotating superficially normal early-A stars, we have discovered that HR 8844 (A0 V) is actually a new chemically peculiar star. We first compared the high-resolution spectrum of HR 8844 with that of four slow rotators near A0V (ν Cap, ν Cnc, Sirius A, and HD 72660) to highlight similarities and differences. The lines of Ti II, Cr II, Sr II, and Ba II are conspicuous features in the high-resolution high signal-to-noise SOPHIE spectra of HR 8844 and much stronger than in the spectra of the normal star ν Cap. The Hg II line at 3983.93 Å is also present in a 3.5% blend. Selected unblended lines of 31 chemical elements from He up to Hg have been synthesized using model atmospheres computed with ATLAS9 and the spectrum synthesis code SYNSPEC48 including hyperfine structure of various isotopes when relevant. These synthetic spectra have been adjusted to the mean SOPHIE spectrum of HR 8844, and high-resolution spectra of the comparison stars. Chi-squares were minimized to derive abundances or upper limits to the abundances of these elements for HR 8844 and the comparison stars. HR 8844 is found to have underabundances of He, C, O, Mg, Ca, and Sc, mild enhancements of Ti, V, Cr, Mn, and distinct enhancements of the heavy elements Sr, Y, Zr, Ba, La, Pr, Sm, Eu, and Hg, the overabundances increasing steadily with atomic number. This chemical pattern suggests that HR 8844 may actually be a new transition object between the coolest HgMn stars and the Am stars.

  7. KANDUNGAN KIMIA SERAT KENAF DARI KOMPOS KULIT UDANG DENGAN PESTISIDA ALAMI KEONG MAS

    Directory of Open Access Journals (Sweden)

    Rusmini Rusmini

    2017-10-01

    Full Text Available Kenaf cultivation generally uses chemical fertilizers and pesticides to increase production despite the adverse effects of those chemicals toward environmental ecosystem. Meanwhile, there are a lot of unutilized wastes produced from agriculture and fishery. Kenaf is an environmentally friendly producer of natural fibers and can produce diversified products, such as paper, wallcover, car interior, geotextile, soil safer, fiber drain, particle board, and plastic reinforcement as well as biofuel industry raw materials. The research aims to produce chemistry fiber kenaf best with the provision of organic fertilizer shrimp compost and natural pesticide snail mas. The study used a Randomized Block Design with two factors with the first factor compost of shrimp (k consisting of 3 levels and the second factor was vegetable pesticide consisting of three levels (p. In each of these studies repeated as many as 2 replications so that there are 18 overall treatment. The observed variables of chemical fiber content include holocellulose, cellulose and lignin. Data obtained, analyzed using analysis of variance  and continued with the smallest real difference test at 5% test level. The results showed that there was holocellulose content in the best kenaf fiber in the treatment of p2 k2 that was equal to 80,28005, for the best cellulose content was p0ko taht was equal to 40,5695 %while for lignin was not continued further test because it showed no real difference. Penanaman  tanaman  kenaf  umumnya menggunakan pupuk kimia untuk meningkatkan produksi, padahal pupuk kimia berbahaya bagi ekosistem lingkungan, sementara banyak sekali limbah pertanian dan perikanan yang tidak termanfaatkan bahkan  menjadi sampah.   Kenaf merupakan tanaman penghasil serat alam yang ramah lingkungan dan bisa menghasilkan berbagai produk diversifikasi, seperti : kertas, pelapis dinding, interior mobil, geotekstil, soil safer, fiber drain, particle board, dan reinforcement plastik

  8. Direct detection and orbital analysis of the exoplanets HR 8799 bcd from archival 2005 Keck/NIRC2 data

    NARCIS (Netherlands)

    Currie, T.; Fukagawa, M.; Thalmann, C.; Matsumura, S.; Plavchan, P.

    2012-01-01

    We present previously unpublished 2005 July H-band coronagraphic data of the young, planet-hosting star HR 8799 from the newly released Keck/NIRC2 archive. Despite poor observing conditions, we detect three of the planets (HR 8799 bcd), two of them (HR 8799 bc) without advanced image processing.

  9. In vivo biodistribution and biological impact of injected carbon nanotubes using magnetic resonance techniques

    Directory of Open Access Journals (Sweden)

    Achraf Al Faraj

    2011-02-01

    Full Text Available Achraf Al Faraj1,2, Florence Fauvelle3, Nathalie Luciani4, Ghislaine Lacroix5, Michael Levy4, Yannick Crémillieux1, Emmanuelle Canet-Soulas1Université Lyon1, Créatis-LRMN, Lyon, France; 2King Saud University, College of Applied Medical Sciences, Radiological Sciences Department, Riyadh, Kingdom of Saudi Arabia; 3CRSSA, Biophysique Cellulaire et Moléculaire, Laboratoire de RMN, La Tronche, France; 4Université Paris7-Paris Diderot, Matières et Systèmes Complexes, Paris, France; 5Institut National de l’Environnement et des Risques Industriels, Verneuil-en-Halatte, FranceBackground: Single-walled carbon nanotubes (SWCNT hold promise for applications as contrast agents and target delivery carriers in the field of nanomedicine. When administered in vivo, their biodistribution and pharmacological profile needs to be fully characterized. The tissue distribution of carbon nanotubes and their potential impact on metabolism depend on their shape, coating, and metallic impurities. Because standard radiolabeled or fluorescently-labeled pharmaceuticals are not well suited for long-term in vivo follow-up of carbon nanotubes, alternative methods are required.Methods: In this study, noninvasive in vivo magnetic resonance imaging (MRI investigations combined with high-resolution magic angle spinning (HR-MAS, Raman spectroscopy, iron assays, and histological analysis ex vivo were proposed and applied to assess the biodistribution and biological impact of intravenously injected pristine (raw and purified and functionalized SWCNT in a 2-week longitudinal study. Iron impurities allowed raw detection of SWCNT in vivo by susceptibility-weighted MRI.Results: A transitional accumulation in the spleen and liver was observed by MRI. Raman spectroscopy, iron assays, and histological findings confirmed the MRI readouts. Moreover, no acute toxicological effect on the liver metabolic profile was observed using the HR-MAS technique, as confirmed by quantitative real

  10. HPV test by Hybrid Capture II for the diagnosis of HR-HPV persistent infection.

    Science.gov (United States)

    Serour, Y; Bendahmane, M; Abbou Baker, F; Medles, M; Moueddene, B; Kraiba, R

    2017-11-01

    Persistent high-risk HPV (HR-HPV) infection is associated with a greater risk of cervical cancer. Statistical data on the prevalence of HR-HPV infections in the Algerian population is lacking. We conducted a prospective study of 300 women aged between 25 and 50 years, screened for cervical cancer from 2012 to 2015 in Sidi Bel Abbès, a western region of Algeria. We aimed to assess the reliability of the repeated use of the HC II test (three longitudinal HPV tests 9 months apart from each other) in diagnosing the persistence of HR-HPV infection. The prevalence of HR-HPV infection was 7.33% and infected women were aged 37.9±3years. For 90.9% of HR-HPV-positive patients, the infection persisted for a mean of 18.5months [95% CI: 16.9-22.1months]. Among these patients, 55.55% developed CIN1 and 11.11% developed CIN2. The sensitivity of the HC II test was 81.74% [95% CI: 71.3-89.6] and its positive predictive value associated with abnormal cervical biopsy was 27.49% [95% CI: 16.0-33.33]. Repeating the HC II test is a good predictor for identifying women at high risk of cervical cancer. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  11. Comparative evaluation of heart rate-based monitors: Apple Watch vs Fitbit Charge HR.

    Science.gov (United States)

    Bai, Yang; Hibbing, Paul; Mantis, Constantine; Welk, Gregory J

    2018-08-01

    The purpose of this investigation was to examine the validity of energy expenditure (EE), steps, and heart rate measured with the Apple Watch 1 and Fitbit Charge HR. Thirty-nine healthy adults wore the two monitors while completing a semi-structured activity protocol consisting of 20 minutes of sedentary activity, 25 minutes of aerobic exercise, and 25 minutes of light intensity physical activity. Criterion measures were obtained from an Oxycon Mobile for EE, a pedometer for steps, and a Polar heart rate strap worn on the chest for heart rate. For estimating whole-trial EE, the mean absolute percent error (MAPE) from Fitbit Charge HR (32.9%) was more than twice that of Apple Watch 1 (15.2%). This trend was consistent for the individual conditions. Both monitors accurately assessed steps during aerobic activity (MAPE Apple : 6.2%; MAPE Fitbit : 9.4%) but overestimated steps in light physical activity. For heart rate, Fitbit Charge HR produced its smallest MAPE in sedentary behaviors (7.2%), followed by aerobic exercise (8.4%), and light activity (10.1%). The Apple Watch 1 had stronger validity than the Fitbit Charge HR for assessing overall EE and steps during aerobic exercise. The Fitbit Charge HR provided heart rate estimates that were statistically equivalent to Polar monitor.

  12. PENGEMBANGAN PERSAMAAN VO2 MAX DAN EVALUASI HR MAX (STUDI AWAL PADA PEKERJA PRIA

    Directory of Open Access Journals (Sweden)

    Purnawan Adi Wicaksono

    2012-10-01

    Full Text Available Kapasitas fisik maksimum seseorang direpresentasikan dengan nilai konsumsi oksigen maksimum (VO2 Max dan denyut nadi maksimum (HR Max yang memberikan suatu informasi batasan kemampuan fisik maksimum seseorang dalam melakukan pekerjaan. Penelitian kali ini mempunyai tujuan untuk mencari nilai VO2 Max pekerja pria Indonesia untuk nantinya akan dikembangkan suatu persamaan prediksi VO2 Max yang didekati dengan hubungan linier antara denyut nadi (Heart Rate seperti yang dilakukan Astrand (2003, tinggi badan (Chatterjee et al, 2006, berat badan (Akalan et al, 2008, usia (Magrani et al, 2009 dan mengevaluasi persamaan HR Max manakah yang dapat diaplikasikan untuk mendekati nilai denyut nadi maksimum pekerja Indonesia. Responden dalam penelitian kali ini adalah 12  pekerja industri pria yang diambil dari beberapa industri di Depok dan sekitarnya. Kriteria responden yang berpartisipasi dalam penelitian kali ini adalah: berusia 20-40 tahun, bukan perokok baik aktif maupun pasif, sehat , tidak mengkonsumsi makanan, kafein, alkohol minimal 2 jam sebelum eksperimen (Balderrama et. al, 2007.Eksperimen yang dilakukan menggunakan metode maximal test dengan protokol treadmill. Adapun peralatan yang digunakan adalah seperangkat alat pengukur kondisi fisiologi Fitmate MED (COSMED srl-Italy terdiri dari Heart Rate Transmitter, Heart Rate Receiver, V mask (Hans Rudolph Inc,dan treadmill SportArt@60.  Eksperimen dilakukan menjadi dua bagian, yaitu istirahat dan tahap bekerja.Aktivitas istirahat terdiri dari tidur selama 20 menit, duduk selama 20 menit dan berdiri selama 10 menit. Eksperimen tahap kedua yaitu tahap kerja yang terdiri dari latihan selama 5 menit. Responden dipersilakan beristirahat selama 15 menit, setelah itu responden melaksanakan maximal test detik hingga responden merasa tidak sanggup lagi melanjutkan eksperimen. Hasil penelitian model prediksi VO2 max untuk pekerja industri pria mempunyai nilai 2,78 ± 0,5 liter/menit dan dengan regresi linier

  13. Experimental investigation of drying characteristics of cornelian cherry fruits ( Cornus mas L.)

    Science.gov (United States)

    Ozgen, Filiz

    2015-03-01

    Major target of present paper is to investigate the drying kinetics of cornelian cherry fruits ( Cornus mas L.) in a convective dryer, by varying the temperature and the velocity of drying air. Freshly harvested fruits are dried at drying air temperature of 35, 45 and 55 °C. The considered drying air velocities are V air = 1 and 1.5 m/s for each temperature. The required drying time is determined by taking into consideration the moisture ratio measurements. When the moisture ratio reaches up to 10 % at the selected drying air temperature, then the time is determined ( t = 40-67 h). The moisture ratio, fruit temperature and energy requirement are presented as the functions of drying time. The lowest drying time (40 h) is obtained when the air temperature is 55 °C and air velocity is 1.5 m/s. The highest drying time (67 h) is found under the conditions of 35 °C temperature and 1 m/s velocity. Both the drying air temperature and the air velocity significantly affect the required energy for drying system. The minimum amount of required energy is found as 51.12 kWh, at 55 °C and 1 m/s, whilst the maximum energy requirement is 106.7 kWh, at 35 °C and 1.5 m/s. It is also found that, air temperature significantly influences the total drying time. Moreover, the energy consumption is decreasing with increasing air temperature. The effects of three parameters (air temperature, air velocity and drying time) on drying characteristics have also been analysed by means of analysis of variance method to show the effecting levels. The experimental results have a good agreement with the predicted ones.

  14. A rheological model for glassforming silicate melts in the systems CAS, MAS, MCAS

    International Nuclear Information System (INIS)

    Giordano, Daniele; Russell, J K

    2007-01-01

    Viscosity is the single most important property governing the efficacy, rates, and nature of melt transport. Viscosity is intimately related to the structure and thermodynamics properties of the melts and is a reflection of the mechanisms of single atoms slipping over potential energy barriers. The ability to predict melt viscosity accurately is, therefore, of critical importance for gaining new insights into the structure of silicate melts. Simple composition melts, having a reduced number of components, offer an advantage for understanding the relationships between the chemical composition, structural organization and the rheological properties of a melt. Here we have compiled a large database of ∼970 experimental measurements of melt viscosity for the simple chemical systems MAS, CAS and MCAS. These data are used to create a single chemical model for predicting the non-Arrhenian viscosity as a function of temperature (T) and composition (X) across the entire MCAS system. The T-dependence of viscosity is accounted for by the three parameters in each of the model functions: (i) Vogel-Fulcher-Tamman (VFT); (ii) Adam-Gibbs (AG); and (iii) Avramov (AV). The literature shows that, in these systems, viscosity converges to a common value of the pre-exponential factors (A) that can be assumed to be independent of composition. The other two adjustable parameters in each equation are expanded to capture the effects of composition. The resulting models are continuous across T-X space. The values and implications of the optimal parameters returned for each model are compared and discussed. A similar approach is likely to be applicable to a variety of non-silicate multicomponent glassforming systems

  15. Reducing radiation dose in liver enhanced CT scan by setting mAs according to plain scan noise

    International Nuclear Information System (INIS)

    Yang Shangwen; He Jian; Yang Xianfeng; Zhou Kefeng; Xin Xiaoyan; Hu Anning; Zhu Bin

    2013-01-01

    Objective: To investigate the feasibility of setting mAs in liver enhanced CT scan according to plain scan noise with fixed mA CT scanner, in order to reduce the radiation dose. Methods: One hundred continuous patients underwent liver enhanced CT scan (group A) prospectively. Two hundred and fifty mAs was used in plain and enhanced CT scans. Noises of plain and venous phase CT images were measured, and the image quality was evaluated. The equation between mAs of enhanced scan and noise of plain scan image was derived. Another 100 continuous patients underwent liver enhanced CT scan (group B). Enhanced scan mAs was calculated from noise on plain scan by using the equation above. Noises on venous phase images were measured and the image quality was measured. Based on body mass index (BMI), patients in groups A and B were divided into three subgroups respectively: BMI < 18.5 kg/m 2 , 18.5 kg/m 2 ≤ BMI < 25.0 kg/m 2 and BMI ≥ 25.0 kg/m 2 . Image quality score was compared with nonparametric rank sum test, CT dose index (CTDI) and effective dose (ED) were measured and compared between each subgroup with 2 independent samples t or t' test. Results: The equation between enhanced scan mAs (mAsX) and plain scan noise (SDp) was as follows: mAsX = mAs1 × [(0.989 × SDp + 1.06) /SDx] 2 , mAs1 = 250 mAs, SDx = 13. In patients with BMI < 18.5 kg/m 2 , ED of group A [(6.86 ± 0.38) mSv, n = 12] was significantly higher than group B [(2.66 ± 0.46) mSv, n = 10)] (t = 18.52, P < 0.01). In patients with 18.5 kg/m 2 ≤ BMI < 25.0 kg/m 2 , ED of group A [(7.08 ± 0.91) mSv, n = 66] was significantly higher than group B [(4.50 ± 1.41) mSv, n = 73] (t' = 10.57, P < 0.01). In patients with BMI ≥ 25.0 kg/m 2 , there was no significant difference between EDs of group A (7.54 ± 0.62 mSv, n = 22) and group B [(8.19 ± 3.16) mSv, n = 17] (t' = 0.89, P = 0.39). Image quality of 5 patients in group A and none in group B did not meet the diagnostic requirement

  16. Site specific health and safety plan, 100-HR-3 pump and treat. Revision 2

    International Nuclear Information System (INIS)

    St John, C.H.

    1997-09-01

    The 100-HR-3 Pump and Treat system is a groundwater remedial action to remove Hexavalent Chromium (Cr+6) from the groundwater underlying the 100-HR-3 Operable Unit. This plan covers operation, maintenance, repairs, resin exchange and equipment removal/installation. The 100-HR-3 Operable Unit addresses groundwater underlying the 100-D Area. The primary groundwater contaminant is Chromium +6. The chromium contamination resulted from the use of sodium dichromate during past reactor operations. Sodium dichromate was used to treat reactor coolant water during reactor operations. The purpose of this Pump and Treat system is to pump contaminated groundwater through above ground ion exchange resin and then return treated water to aquifer. Chromium levels extracted from the wells are anticipated to range in the low parts per billion (∼50 ppb) which is the drinking water limit for Cr+6

  17. Qualitative risk assessment for the 100-HR-3 groundwater operable unit

    Energy Technology Data Exchange (ETDEWEB)

    Vukelich, S.E. [Golder Associates, Inc., Richland, WA (United States)

    1994-09-22

    This report provides the qualitative risk assessment for the 100-HR-3 operable unit on the Hanford Reservation. 100-HR-3 is a ground water unit. The purpose of the QRA at the 100-HR-3 operable unit is to focus on a predefined set of human and environmental exposure scenarios in order to provides sufficient information that will assist the Tri-Party signatories (Washington State Department of Ecology, EPA and US DOE) in making defensible decisions on the necessity of Interim Remedial Measures. Frequent- and occasional-use exposure scenarios are evaluated in the human health risk assessment to provide bounding estimates of risk. The ecological risk assessment consists of an evaluation of the risks to riparian and aquatic receptors which live in or near the Columbia River.

  18. A Role For HR In Corporate Ethics? South African Practitioners’ Perspectives

    Directory of Open Access Journals (Sweden)

    L. J. van Vuuren

    2006-11-01

    Full Text Available Since few South African organisations have as yet appointed ethics officers, there is often a lack of clarity on who should take responsibility for coordinating organisations’ ethics management efforts. The purpose of this paper was to assess HR (the Human Resource function and its practitioners as a possible contender to assume responsibility for ethics management in SA organisations. To this end a mail survey was conducted among registered HR practitioners (N=410. Two factors related to 1 the extent of HR’s ethics management competence and 2 HR’s responsibility for ethics management, were identified. The results showed that HR practitioners on average believe that they indeed have an ethics management competence and that they should be involved in ethics management. However, practitioners with a great deal of exposure to organisations that manage ethics believe to a lesser extent that they should be involved in ethics management. The implications of the findings are discussed.

  19. Qualitative risk assessment for the 100-HR-3 groundwater operable unit

    International Nuclear Information System (INIS)

    Vukelich, S.E.

    1994-01-01

    This report provides the qualitative risk assessment for the 100-HR-3 operable unit on the Hanford Reservation. 100-HR-3 is a ground water unit. The purpose of the QRA at the 100-HR-3 operable unit is to focus on a predefined set of human and environmental exposure scenarios in order to provides sufficient information that will assist the Tri-Party signatories (Washington State Department of Ecology, EPA and US DOE) in making defensible decisions on the necessity of Interim Remedial Measures. Frequent- and occasional-use exposure scenarios are evaluated in the human health risk assessment to provide bounding estimates of risk. The ecological risk assessment consists of an evaluation of the risks to riparian and aquatic receptors which live in or near the Columbia River

  20. Experimental article – Reducing effective dose to a paediatric phantom by using different combinations of kVp, mAs and additional filtration whilst maintaining image quality

    NARCIS (Netherlands)

    Huizinga, Elsbeth; Schaake, Wouter; Visser, Ruurd; Bloomfield, Charlotte; Boavida, Filipa; Chabloz, Diane; Crausaz, Emilie; Hustveit, Hanne; Knight, Heidi; Pereira, Anna; Harsaker, Vanja

    2015-01-01

    Purpose: To determine whether using different combinations of kVp and mAs with additional filtration can reduce the effective dose to a paediatric phantom whilst maintaining diagnostic image quality. Methods: 27 images of a paediatric AP pelvis phantom were acquired with different kVp, mAs and

  1. Experimental article – Reducing effective dose to a paediatric phantom by using different combinations of kVp, mAs and additional filtration whilst maintaining image quality

    NARCIS (Netherlands)

    Elsbeth Huizinga; Ana Pereira; Wouter Schaake; Charlotte Bloomfield; Heidi Knight; Emilie Crausaz; Hanne Hustveit; Ruurd Visser; Vanja Harsaker; Diane Chabloz; Filipa Boavida

    2015-01-01

    Purpose: To determine whether using different combinations of kVp and mAs with additional filtration can reduce the effective dose to a paediatric phantom whilst maintaining diagnostic image quality. Methods: 27 images of a paediatric AP pelvis phantom were acquired with different kVp, mAs

  2. Who Are the Students Who May Qualify for an Alternate Assessment Based on Modified Academic Achievement Standards (AA-MAS)?: Focus Group Results. Synthesis Report 79

    Science.gov (United States)

    Berndt, Sandra; Ebben, Barbara; Kubinski, Eva; Sim, Grant; Liu, Kristin; Lazarus, Sheryl; Thurlow, Martha; Christian, Elizabeth

    2011-01-01

    Beginning in 2007, federal regulations to two major education laws gave state departments of education the option to develop an alternate assessment based on modified achievement standards (AA-MAS) for some students with disabilities. The regulations stated that the AA-MAS was intended for students who were being instructed in the grade-level…

  3. Lifetime validation of high-reliability (>30,000hr) rotary cryocoolers for specific customer profiles

    Science.gov (United States)

    Cauquil, Jean-Marc; Seguineau, Cédric; Vasse, Christophe; Raynal, Gaetan; Benschop, Tonny

    2018-05-01

    The cooler reliability is a major performance requested by the customers, especially for 24h/24h applications, which are a growing market. Thales has built a reliability policy based on accelerate ageing and tests to establish a robust knowledge on acceleration factors. The current trend seems to prove that the RM2 mean time to failure is now higher than 30,000hr. Even with accelerate ageing; the reliability growth becomes hardly manageable for such large figures. The paper focuses on these figures and comments the robustness of such a method when projections over 30,000hr of MTTF are needed.

  4. Clinical evaluation of wide-latitude HR-C film for chest radiography

    International Nuclear Information System (INIS)

    Kim, Young Sung; Hwang, Nam Sun; Yeo, Young Bok; Lee, In Ja; Huh, Joon

    1990-01-01

    In application of wide latitude HR-C film to chest x-ray examination, former x-ray diagnosis area is larger and diagnostic information has great deal of promotion. HR-C film is compare to former x-ray film is larger latitude and density level is small, reading is very easily. Especially, high estimate that is in characteristic curve linearity of toe part is good, contrast of low density made good shape and not good describe to overlap is diagnostic information increase mediastinum portion etc

  5. Validation of calcaneus trabecular microstructure measurements by HR-pQCT.

    Science.gov (United States)

    Metcalf, Louis M; Dall'Ara, Enrico; Paggiosi, Margaret A; Rochester, John R; Vilayphiou, Nicolas; Kemp, Graham J; McCloskey, Eugene V

    2018-01-01

    Assessment of calcaneus microstructure using high-resolution peripheral quantitative computed tomography (HR-pQCT) might be used to improve fracture risk predictions or to assess responses to pharmacological and physical interventions. To develop a standard clinical protocol for the calcaneus, we validated calcaneus trabecular microstructure measured by HR-pQCT against 'gold-standard' micro-CT measurements. Ten human cadaveric feet were scanned in situ using HR-pQCT (isotropic 82μm voxel size) at 100, 150 and 200ms integration times, and at 100ms integration time following removal of the calcaneus from the foot (ex vivo). Dissected portions of these bones were scanned using micro-computed tomography (micro-CT) at an isotropic 17.4μm voxel size. HR-pQCT images were rigidly registered to those obtained with micro-CT and divided into multiple 5mm sided cubes to evaluate and compare morphometric parameters between the modalities. Standard HR-pQCT measurements (derived bone volume fraction (BV/TV d ); trabecular number, Tb.N; derived trabecular thickness, Tb.Th d ; derived trabecular spacing, Tb.Sp d ) and corresponding micro-CT voxel-based measurements (BV/TV, Tb.N, Tb.Th, Tb.Sp) were compared. A total of 108 regions of interest were analysed across the 10 specimens. At all integration times HR-pQCT BV/TV d was strongly correlated with micro-CT BV/TV (r 2 =0.95-0.98, RMSE=1%), but BV/TV d was systematically lower than that measured by micro-CT (mean bias=5%). In contrast, HR-pQCT systematically overestimated Tb.N at all integration times; of the in situ scans, 200ms yielded the lowest mean bias and the strongest correlation with micro-CT (r 2 =0.61, RMSE=0.15mm -1 ). Regional analysis revealed greater accuracy for Tb.N in the superior regions of the calcaneus at all integration times in situ (mean bias=0.44-0.85mm -1 ; r 2 =0.70-0.88, pmicrostructure, particularly in the superior region of the calcaneus, can be assessed by HR-pQCT. The highest integration time

  6. The Phenomenon of Climate Change in Organization and HR- Related Literature: A Conceptual Brief Analysis

    Directory of Open Access Journals (Sweden)

    Mousa Mohamed

    2018-05-01

    Full Text Available Climate change has become one of the main challenges facing humanity. Over the past decade, this phenomenon, which may have been caused by natural variability and/or human activity, has attracted many scholars from different scientific disciplines to warn of its potential consequences. The author of this paper has decided to address the existence of this important phenomenon in organizational literature. However, upon exploring different academic databases, the rarity of research focusing on climate change and its relationship and/or effect on HR or organizational aspects became obvious. Accordingly, the author recommends other HR and organizational scholars devote considerable space to this phenomenon in their field.

  7. How can HR practices support front-end innovation and increase the innovativeness of companies?

    DEFF Research Database (Denmark)

    Aagaard, Annabeth; Andersen, Torben

    2014-01-01

    to be reinterpreted in a context of heterogeneity and polyvalence. Finally performance management and talent management should play a greater role in emphasising exclusive values and rational goal-oriented behaviour among employees, compared to the more inclusive mainstream values that characterise much HRM......' innovativeness. If HR is to support these activities, focus should be on broader issues such as team-based organising, founded on a questioning attitude and a management style with a high level of empowerment. In addition, traditional HR themes such as recruitment, training and development have...

  8. MUNICIPAL ENVIRONMENTAL MANAGEMENT: A PROPOSAL OF INSTRUMENTS FOR DIAGNOSIS OF PUBLIC ENVIRONMENTAL POLICIES IN THE METROPOLITAN AREA OF SALVADOR (MAS

    Directory of Open Access Journals (Sweden)

    Tânia Cristina Azevedo

    2016-04-01

    Full Text Available The aim in this paper is to propose a model for mapping strategies of municipal environmental management for local environmental public policies. To do so, the study adopted a theoretical approach. More specifically, there is discussion on the concepts of public policies and the scenario of the Brazilian municipal environmental management, a brief history of the aspects that involve current national environmental policies. Methodologically, a bibliographical study was carried out through a literature review, which enabled the proposal of instruments for mapping actions and strategies of environmental management in the municipalities of the Metropolitan Area of Salvador (MAS. This theoretical study resulted in the creation of a model form that will be used by empirical researches for mapping the environmental public policies in the MAS City Halls.

  9. Characterizing crystal disorder of trospium chloride: a comprehensive,(13) C CP/MAS NMR, DSC, FTIR, and XRPD study.

    Science.gov (United States)

    Urbanova, Martina; Sturcova, Adriana; Brus, Jiri; Benes, Hynek; Skorepova, Eliska; Kratochvil, Bohumil; Cejka, Jan; Sedenkova, Ivana; Kobera, Libor; Policianova, Olivia; Sturc, Antonin

    2013-04-01

    Analysis of C cross-polarization magic angle spinning (CP/MAS) nuclear magnetic resonance (NMR), differential scanning calorimetry (DSC), Fourier transform infrared (FTIR), and X-ray powder diffraction data of trospium chloride (TCl) products crystallized from different mixtures of water-ethanol [φ(EtOH) = 0.5-1.0] at various temperatures (0°C, 20°C) and initial concentrations (saturated solution, 30%-50% excess of solvent) revealed extensive structural variability of TCl. Although (13) C CP/MAS NMR spectra indicated broad variety of structural phases arising from molecular disorder, temperature-modulated DSC identified presence of two distinct components in the products. FTIR spectra revealed alterations in the hydrogen bonding network (ionic hydrogen bond formation), whereas the X-ray diffraction reflected unchanged unit cell parameters. These results were explained by a two-component character of TCl products in which a dominant polymorphic form is accompanied by partly separated nanocrystalline domains of a secondary phase that does not provide clear Bragg reflections. These phases slightly differ in the degree of molecular disorder, in the quality of crystal lattice and hydrogen bonding network. It is also demonstrated that, for the quality control of such complex products, (13) C CP/MAS NMR spectroscopy combined with factor analysis (FA) can satisfactorily be used for categorizing the individual samples: FA of (13) C CP/MAS NMR spectra found clear relationships between the extent of molecular disorder and crystallization conditions. © 2013 Wiley Periodicals, Inc. and the American Pharmacists Association J Pharm Sci 102:1235-1248, 2013. Copyright © 2013 Wiley Periodicals, Inc.

  10. Analisis Laporan Keuangan Untuk Menilai Kinerja Keuangan PT. Sinar Mas Agro Resources and Technology. Tbk periode 2009, 2010 dan 2011

    OpenAIRE

    Monica, Marnala Stevi

    2015-01-01

    This study aims to look at how the development of the financial performance. Sinar Mas Agro Resources and Technology. Tbk for 3 years ie 2009, 2010 and 2011. In assessing the financial performance of the financial statements required to be analyzed. Financial statement analysis can be done using financial ratio analysis. Financial ratios are used in assessing the financial performance of this is the Current Ratio, Quick Ratio, Debt to Equity Ratio (DER), Debt to Asset Ratio (DAR), Total Asset...

  11. Genotyping-by-sequencing (GBS), an ultimate marker-assisted selection (MAS) tool to accelerate plant breeding

    OpenAIRE

    He, Jiangfeng; Zhao, Xiaoqing; Laroche, André; Lu, Zhen-Xiang; Liu, HongKui; Li, Ziqin

    2014-01-01

    Marker-assisted selection (MAS) refers to the use of molecular markers to assist phenotypic selections in crop improvement. Several types of molecular markers, such as single nucleotide polymorphism (SNP), have been identified and effectively used in plant breeding. The application of next-generation sequencing (NGS) technologies has led to remarkable advances in whole genome sequencing, which provides ultra-throughput sequences to revolutionize plant genotyping and breeding. To further broad...

  12. Characterization of solid polymer dispersions of active pharmaceutical ingredients by 19F MAS NMR and factor analysis

    Czech Academy of Sciences Publication Activity Database

    Urbanová, Martina; Brus, Jiří; Šeděnková, Ivana; Policianová, Olivia; Kobera, Libor

    2013-01-01

    Roč. 100, 1 January (2013), s. 59-66 ISSN 1386-1425 R&D Projects: GA ČR GPP106/11/P426; GA MŠk 2B08021 Institutional research plan: CEZ:AV0Z40500505 Institutional support: RVO:61389013 Keywords : solid-state NMR * factor analysis * 19F MAS NMR Subject RIV: FR - Pharmacology ; Medidal Chemistry Impact factor: 2.129, year: 2013

  13. 1 H MAS NMR study of structure of hybrid siloxane-based networks and the interaction with quartz filler

    Czech Academy of Sciences Publication Activity Database

    Brus, Jiří; Škrdlantová, M.

    2001-01-01

    Roč. 281, 1-3 (2001), s. 61-71 ISSN 0022-3093 R&D Projects: GA ČR GA203/98/P290; GA AV ČR KSK2050602 Institutional research plan: CEZ:AV0Z4050913 Keywords : hybrid siloxane networks * 1 H MAS NMR spectroscopy * hydrogen bonds Subject RIV: CD - Macromolecular Chemistry Impact factor: 1.363, year: 2001

  14. Role of Mas receptor in renal blood flow response to angiotensin (1-7) in male and female rats.

    Science.gov (United States)

    Nematbakhsh, Mehdi; Safari, Tahereh

    2014-01-01

    Epidemiologic and clinical studies have shown that progression of renal disease in male is faster than that in female. However, the exact mechanisms are not well recognized. Angiotensin (1-7) (Ang 1-7) receptor, called "Mas", is an element in the depressor arm of renin angiotensin system (RAS), and its expression is enhanced in females. We test the hypothesis that Mas receptor (MasR) blockade (A779) attenuates renal blood flow (RBF) in response to infusion of graded doses of Ang 1-7 in female rats. Male and female Wistar rats were anesthetized and catheterized. Then, the mean arterial pressure (MAP), RBF, and controlled renal perfusion pressure (RPP) responses to infusion of graded doses of Ang 1-7 (100-1000 ng/kg/min i.v.) with and without A779 were measured in the animals. Basal MAP, RPP, RBF, and renal vascular resistance (RVR) were not significantly different between the two groups. After Ang 1-7 administration, RPP was controlled at a constant level. However, RBF increased in a dose-related manner in response to Ang 1-7 infusion in both male and female rats (Pdoserenal diseases.

  15. Stilistiskie izteiksmes līdzekļi Coca-Cola reklāmas plakātos

    OpenAIRE

    Gudre, Anete

    2017-01-01

    Šajā darbā tika pētīti mākslinieciskie un fonētiskie stila izteiksmes līdzekļi un to lietojums Coca-Cola reklāmas plakātos. Kā arī tika analizēti Coca-Cola reklāmas plakātu vizuālie elementi. Tēma tika izvēlēta, lai redzētu atšķirību starp mākslinieciskās izteiksmes līdzekļiem un, lai redzētu, cik bieži tie tiek izmantoti izvēlētajos reklāmas plakātos. Darbā tika aplūkoti vispopulārākie mākslinieciskās izteiksmes līdzekļi – metafora, epitets, personifikācija un hiperbola. Multimediju analīze ...

  16. Quality of Kelantan drinking water and knowledge, attitude and practice among the population of Pasir Mas, Malaysia.

    Science.gov (United States)

    Ab Razak, N H; Praveena, S M; Aris, A Z; Hashim, Z

    2016-02-01

    Information about the quality of drinking water, together with analysis of knowledge, attitude and practice (KAP) analysis and health risk assessment (HRA) remain limited. The aims of this study were: (1) to ascertain the level of KAP regarding heavy metal contamination of drinking water in Pasir Mas; (2) to determine the concentration of heavy metals (Al, Cr, Cu, Fe, Ni, Pb, Zn and Cd) in drinking water in Pasir Mas; and (3) to estimate the health risks (non-carcinogenic and carcinogenic) caused by heavy metal exposure through drinking water using hazard quotient and lifetime cancer risk. Information on KAP was collected using a standardized questionnaire. Heavy metal analysis of drinking water samples was performed using graphite furnace atomic absorption spectrophotometry. The population of Pasir Mas has good knowledge (80%), a less positive attitude (93%) and good practice (81%) towards heavy metal contamination of drinking water. The concentrations of heavy metals analysed in this study were found to be below the permissible limits for drinking water set by the Malaysian Ministry of Health and the World Health Organization. The HRA showed no potential non-carcinogenic and carcinogenic risks from the intake of heavy metal through drinking water. By investigating the quality of drinking water, KAP and HRA, the results of this study will provide authorities with the knowledge and resources to improve the management of drinking water quality in the future. Copyright © 2015 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  17. A new aluminium-hydrate species in hydrated Portland cements characterized by 27Al and 29Si MAS NMR spectroscopy

    International Nuclear Information System (INIS)

    Andersen, Morten Daugaard; Jakobsen, Hans J.; Skibsted, Jorgen

    2006-01-01

    Recent 27 Al MAS NMR studies of hydrated Portland cements and calcium-silicate-hydrate (C-S-H) phases have shown a resonance from Al in octahedral coordination, which cannot be assigned to the well-known aluminate species in hydrated Portland cements. This resonance, which exhibits the isotropic chemical shift δ iso = 5.0 ppm and the quadrupole product parameter P Q = 1.2 MHz, has been characterized in detail by 27 Al MAS and 27 Al{ 1 H} CP/MAS NMR for different hydrated white Portland cements and C-S-H phases. These experiments demonstrate that the resonance originates from an amorphous or disordered aluminate hydrate which contains Al(OH) 6 3- or O x Al(OH) 6-x (3+x)- units. The formation of the new aluminate hydrate is related to the formation of C-S-H at ambient temperatures, however, it decomposes by thermal treatment at temperatures of 70-90 o C. From the experiments in this work it is proposed that the new aluminate hydrate is either an amorphous/disordered aluminate hydroxide or a calcium aluminate hydrate, produced as a separate phase or as a nanostructured surface precipitate on the C-S-H phase. Finally, the possibilities of Al 3+ for Ca 2+ substitution in the principal layers and interlayers of the C-S-H structure are discussed

  18. Managing aging workers: a mixed methods study on bundles of HR practices for aging workers

    NARCIS (Netherlands)

    Kooij, Dorien T. A. M.; Jansen, Paul G. W.; Dikkers, Josje S. E.; de Lange, Annet H.

    2014-01-01

    Since abilities and motives change with age and common human resource (HR) practices might be less suitable for aging employees, scholars and practitioners are currently challenged to find new ways of managing aging workers and motivating them to continue working. Therefore, this mixed methods study

  19. The composite nature of the peculiar star HR 6560 (HD 159870)

    Science.gov (United States)

    Wegner, Gary; Cowley, Charles R.

    1992-01-01

    Ground-based high-dispersion photographic spectra and ultraviolet spectra obtained with the IUE satellite are described and employed to determine the nature of the peculiar star HR 6560 (HD 159870). Previously this object had been described as both a composite system and as a strong Fm star. The UBVRI, Stromgren, and ultraviolet colors of HR 6560 are compared with objects classified composite from the Bright Star Catalogue and normal dwarfs and giants. The colors of HR 6560 are not unusual for a composite and are consistent with a late-A dwarf, combined with a late-G or early-K giant. The ultraviolet satellite clearly shows the presence of an A component, but its precise spectral type is difficult to assign. The IUE and TD-1 data suggest that the ultraviolet is dominated by light from an A5 V secondary and the visual from a GO III primary. This does not agree well with the most plausible model that fits the visual photometry. The peculiar nature of HR 6560's spectrum is most likely due to its composite nature.

  20. Getting People Involved: The Benefit of Intellectual Capital Management for Addressing HR Challenges

    Science.gov (United States)

    Pook, Katja

    2011-01-01

    Purpose: This paper aims to explore the benefits of intellectual capital assessment for facing current challenges of human resources work and organizational development. Design/methodology/approach: The paper takes findings of studies on challenges in HR work and maps them with features of intellectual capital assessment methods. It is thus a…

  1. Mitigation action plan for the 100-HR-3 and 100-KR-4 pump and treat project

    International Nuclear Information System (INIS)

    1996-11-01

    This project involves drilling 22 wells, improving access roads to existing and new wells, laying connecting pipes, and constructing groundwater treatment facilities in the 100-KR-4 Area and 100-HR-3 Operable Units. Drilling is expected to be completed by September 1996, but the treatment operations will continue for approximately 10 years

  2. HR Technology Tools: Less Time on Paper and More on People

    Science.gov (United States)

    Tillman, Tom

    2009-01-01

    Many human resource managers face a dilemma. They would like to spend more time improving the overall work environment for employees. They want to help their executives save on workforce-related expenses, find and hire better talent, and improve existing talent through training and development. Unfortunately, most days, HR managers are stuck doing…

  3. HR professionals exploring cooperative configurational human resource management using a serious game: what do they miss?

    NARCIS (Netherlands)

    Collou, Luuk Dirk; Bruinsma, Guido Wybe Jan; van Riemsdijk, Maarten

    2017-01-01

    Configurational thinking in HRM is expected to increase understanding of the HRM-firm performance link and potentially aid HR professionals in the complex task of designing effective HRM. Here, we specify configurational theory in HRM to a level of detail that has been lacking. We present two

  4. CERN HR receives award for on-line recruitment and communication

    CERN Multimedia

    Joannah Caborn Wengler

    2012-01-01

    In a survey of 21,000 European students, CERN ranked 15th, ahead of giants like Microsoft and Nestlé, for the quality of its on-line "talent communication", that is how it uses the Internet to attract job applicants. HR now boasts a new virtual award, certifying its on-line savvy.   The "virtual" award given to HR. How did you get your job at CERN? Via the CERN HR website, or Facebook, or Twitter? Or were you headhunted on LinkedIn? Particularly if you’re from the younger generation, chances are that you used some form of on-line recruitment. In this case you will have used one of the best recruitment tools in Europe, according to the 2012 OTaC (Online Talent Communication) study, carried out by a research institute named Potentialpark. It surveyed over 21,000 students, asking them to rate employers’ use of seven different channels of communication about jobs and careers, from HR websites and on-line application systems to the...

  5. The effect of individual HR domains on financial performance : Evidence from Belgian small businesses

    NARCIS (Netherlands)

    Faems, D; Sels, L; De Winne, S; Maes, J

    2005-01-01

    The contribution of this study, which assesses the influence of HRM on financial performance, is fourfold. (1) We assess the relative contribution of different HR domains to organizational performance. By controlling for the overall HRM intensity in all analyses we try to meet one of the most

  6. Creep properties of simulated heat-affected zone of HR3C austenitic steel

    Czech Academy of Sciences Publication Activity Database

    Sklenička, Václav; Kuchařová, Květa; Kvapilová, Marie; Svoboda, Milan; Král, Petr; Dvořák, Jiří

    2017-01-01

    Roč. 128, JUN (2017), s. 238-247 ISSN 1044-5803 R&D Projects: GA MŠk(CZ) LQ1601 Institutional support: RVO:68081723 Keywords : HR3C steel * Welding * Heat affected zone * Creep * Microstructure * Fractography Subject RIV: JG - Metallurgy OBOR OECD: Materials engineering Impact factor: 2.714, year: 2016

  7. Organizations' ways of employing early retirees: the role of age-based HR policies

    NARCIS (Netherlands)

    Oude Mulders, J.; Henkens, K.; Schippers, J.

    2015-01-01

    Purpose of the Study: We examine whether from an organizational perspective it is possible to distinguish different ways of employing early retirees and explore how the employment of early retirees is related to the application of 4 age-based human resource (HR) policies, namely demotion, offering

  8. Linking educational leadership styles to the HR architecture for new teachers in primary education.

    Science.gov (United States)

    Vekeman, Eva; Devos, Geert; Valcke, Martin

    2016-01-01

    This study aims to gain insight in the relationship between principals' leadership styles and the configuration of different HR practices for new teachers in primary education. Besides the longstanding interest in educational leadership as a key element in teacher and student performance, there is a growing interest in strategic human resource management (SHRM) in the educational sector. However, few educational studies link educational leadership to SHRM. In particular, this study examines the relationship between principals' instructional and transformational leadership style and principals' strategic and HR orientation in configuring HR practices for new teachers. Data were gathered using a mixed methods approach, including interviews with 75 principals as well as an online survey of 1058 teachers in Flemish primary education. Qualitative interview data were transformed and analysed together with the quantitative survey data using logistic regression and ANOVA analyses. The results indicate that both instructional and transformational leadership is associated with the strategic orientation of principals. The HR orientation, on the other hand, is not reflected in the principals' leadership style. Recommendations for further research in this area are discussed.

  9. 1+1=3 De kansen van samenwerking tussen wetenschap en praktijk bij HR analytics

    NARCIS (Netherlands)

    Charissa Freese; Sjoerd van den Heuvel

    2017-01-01

    Wanneer we over HRM en technologie spreken, kunnen we niet meer heen om HR analytics. Gefaciliteerd door de alsmaar groeiende hoeveelheid beschikbare data, oftewel Big Data, proberen organisaties momenteel volop waardevolle inzichten uit de bijna oneindige hoeveelheid data te genereren. Samenwerking

  10. Organizations' Ways of Employing Early Retirees : The Role of Age-Based HR Policies

    NARCIS (Netherlands)

    Oude Mulders, Jaap; Henkens, Kène; Schippers, Joop

    PURPOSE OF THE STUDY: We examine whether from an organizational perspective it is possible to distinguish different ways of employing early retirees and explore how the employment of early retirees is related to the application of 4 age-based human resource (HR) policies, namely demotion, offering

  11. Risk management is every managers’ responsibility: Are HR practitioners ready for the challenge

    Directory of Open Access Journals (Sweden)

    Pascal Siphelele Zulu

    2014-07-01

    Full Text Available Risk and Enterprise Risk Management has become a strategic imperative in most organisations and government departments over the years. Most company boards and government entities in South Africa have adopted various corporate governance frameworks as a mechanism to direct and control the operations of their organisations. As a result, risk management and enterprise risk management has become every manager’s responsibility. The key question that the study investigates is whether HR managers are aware of this strategic imperative and ready to be risk champions in their environment. Data was collected from forty eight (48 HR Managers and Practitioners from private companies and sixty eight (68 HR Managers and Practitioners from government departments and government companies in Durban, Kwazulu-Natal and Cape Town, Western Cape using both personal interviews and questionnaires which were distributed to one hundred and fifty (150 employees, of which one hundred and sixteen (116 questionnaires were completed (return rate 77.3%. The results of this paper indicate that, in general and across all sectors, HR practitioners’ levels of understanding of corporate governance and risk management is limited

  12. Role of RENAL nephrometry scoring system in planning surgical intervention in patients with localized renal mas

    OpenAIRE

    Mohamed Samir Shaaban; Tamer Mohammed Abou Youssif; Ahmed Mostafa; Hossam Eldin Hegazy; Mohammed Adel Atta

    2015-01-01

    Purpose: The study was designed to validate the value of preoperative planning using RENAL nephrometry scoring system in patients having organ confined renal tumors and undergoing surgical intervention and to assess its correlation with the surgical technique. Patient and methods: Forty patients with organ-confined renal masses underwent RENAL nephrometry scoring which was correlated with the surgical technique either radical or nephron-sparing surgery. Result: RENAL nephrometry scoring...

  13. Daily self-sampling for high-risk human papillomavirus (HR-HPV) testing.

    Science.gov (United States)

    Sanner, Karin; Wikström, Ingrid; Gustavsson, Inger; Wilander, Erik; Lindberg, Julia Hedlund; Gyllensten, Ulf; Olovsson, Matts

    2015-12-01

    Self-sampling for HPV as part of primary screening is a well-tolerated method for women not attending organized Pap smear screening and could increase coverage of cervical cancer screening. To investigate if the prevalence of HR-HPV varies from day to day in infected women and if one single sample is reliable for detecting an ongoing infection. This is a prospective cohort study on 12 premenopausal and 13 postmenopausal women performing daily self-sampling for HR-HPV testing. They were all HR-HPV-positive 1-3 months ago. Postmenopausal women were sampled for 28 days and premenopausal women sampled during bleeding-free days in one menstrual cycle. A possible difference in viral load between the estrogen-dominated proliferative phase and the progesterone-dominated secretory phase was analyzed. Consistent results throughout the sampling period were observed for 19 women, with either a daily presence of HPV (14 women) or no HPV at all during the sampling period (5 women). Of 607 samples from 25 women, 596 were consistently positive or negative for HPV during the sampling period and 11 were inconsistent (2%). There was no difference in HPV copy number between the estrogen dominated proliferative or progesterone dominated secretory menstrual cycle phases. The major finding was a high degree of consistency concerning HR-HPV positivity and negativity of HR-HPV in vaginal fluid during a sustained period of daily self-sampling. It does not appear to matter whether the sample is collected in the proliferative or secretory phase. Copyright © 2015 Elsevier B.V. All rights reserved.

  14. Design of the high resolution optical instrument for the Pleiades HR Earth observation satellites

    Science.gov (United States)

    Lamard, Jean-Luc; Gaudin-Delrieu, Catherine; Valentini, David; Renard, Christophe; Tournier, Thierry; Laherrere, Jean-Marc

    2017-11-01

    As part of its contribution to Earth observation from space, ALCATEL SPACE designed, built and tested the High Resolution cameras for the European intelligence satellites HELIOS I and II. Through these programmes, ALCATEL SPACE enjoys an international reputation. Its capability and experience in High Resolution instrumentation is recognised by the most customers. Coming after the SPOT program, it was decided to go ahead with the PLEIADES HR program. PLEIADES HR is the optical high resolution component of a larger optical and radar multi-sensors system : ORFEO, which is developed in cooperation between France and Italy for dual Civilian and Defense use. ALCATEL SPACE has been entrusted by CNES with the development of the high resolution camera of the Earth observation satellites PLEIADES HR. The first optical satellite of the PLEIADES HR constellation will be launched in mid-2008, the second will follow in 2009. To minimize the development costs, a mini satellite approach has been selected, leading to a compact concept for the camera design. The paper describes the design and performance budgets of this novel high resolution and large field of view optical instrument with emphasis on the technological features. This new generation of camera represents a breakthrough in comparison with the previous SPOT cameras owing to a significant step in on-ground resolution, which approaches the capabilities of aerial photography. Recent advances in detector technology, optical fabrication and electronics make it possible for the PLEIADES HR camera to achieve their image quality performance goals while staying within weight and size restrictions normally considered suitable only for much lower performance systems. This camera design delivers superior performance using an innovative low power, low mass, scalable architecture, which provides a versatile approach for a variety of imaging requirements and allows for a wide number of possibilities of accommodation with a mini

  15. KEBIJAKAN INVESTASI ASING BIDANG PERTAMBANGAN DI KABUPATEN POHUWATO PROVINSI GORONTALO KEBIJAKAN INVESTASI ASING BIDANG PERTAMBANGAN DI KABUPATEN POHUWATO PROVINSI GORONTALO KEBIJAKAN INVESTASI ASING BIDANG PERTAMBANGAN DI KABUPATEN POHUWATO PROVINSI GORONTALO KASUS PT. PANI DHARMA MAS KASUS PT. PANI DHARMA MAS KASUS PT. PANI DHARMA MAS

    OpenAIRE

    PUYO, AJENG MAWADDAH PUYO AJENG MAWADDAH PUYO AJENG MAWADDAH

    2016-01-01

    2016 AJENG MAWADDAH PUYO, E 131 12 003, "Kebijakan Investasi Asing Dalam Bidang Pertambangan di Kabupaten Pohuwato Provinsi Gorontalo Kasus PT. Pani Dharma MAS", dibawah bimbingan Dr. H. Adi Suryadi B., MA selaku pembimbing I dan Pusparida Syahdan. S.sos., MSI, Departemen Ilmu Hubungan internasional, Fakultas Ilmu Sosial dan Ilmu Politik, Universitas Hasanuddin. Penelitian ini bertujuan untuk mengetahui peran stakeholders dalam perumusan kebijakan investasi asing da...

  16. ACE-2/Ang1-7/Mas cascade mediates ACE inhibitor, captopril, protective effects in estrogen-deficient osteoporotic rats.

    Science.gov (United States)

    Abuohashish, Hatem M; Ahmed, Mohammed M; Sabry, Dina; Khattab, Mahmoud M; Al-Rejaie, Salim S

    2017-08-01

    The local role of the renin angiotensin system (RAS) was documented recently beside its conventional systemic functions. Studies showed that the effector angiotensin II (AngII) alters bone health, while inhibition of the angiotensin converting enzyme (ACE-1) preserved these effects. The newly identified Ang1-7 exerts numerous beneficial effects opposing the AngII. Thus, the current study examines the role of Ang1-7 in mediating the osteo-preservative effects of ACEI (captopril) through the G-protein coupled Mas receptor using an ovariectomized (OVX) rat model of osteoporosis. 8 weeks after the surgical procedures, captopril was administered orally (40mgkg -1 d -1 ), while the specific Mas receptor blocker (A-779) was delivered at infusion rate of 400ngkg -1 min -1 for 6 weeks. Bone metabolic markers were measured in serum and urine. Minerals concentrations were quantified in serum, urine and femoral bones by inductive coupled plasma mass spectroscopy (ICP-MS). Trabecular and cortical morphometry was analyzed in the right distal femurs using micro-CT. Finally, the expressions of RAS peptides, enzymes and receptors along with the receptor activator of NF-κB ligand (RANKL) and osteoprotegerin (OPG) were determined femurs heads. OVX animals markedly showed altered bone metabolism and mineralization along with disturbed bone micro-structure. Captopril significantly restored the metabolic bone bio-markers and corrected Ca 2+ and P values in urine and bones of estrogen deficient rats. Moreover, the trabecular and cortical morphometric features were repaired by captopril in OVX groups. Captopril also improved the expressions of ACE-2, Ang1-7, Mas and OPG, while abolished OVX-induced up-regulation of ACE-1, AngII, Ang type 1 receptor (AT1R) and RANKL. Inhibition of Ang1-7 cascade by A-779 significantly eradicated captopril protective effects on bone metabolism, mineralization and micro-structure. A-779 also restored OVX effects on RANKL expression and ACE-1/AngII/AT1R

  17. Effect of chronic smoking on lens nucleus as assessed by Pentacam HR lens densitometry in young adults.

    Science.gov (United States)

    Pekel, Gökhan; Cetin, Ebru Nevin; Acer, Semra; Yagci, Ramazan; Altintas, Seher; Ongun, Gülin Tugba

    2014-06-01

    To evaluate the effects of chronic tobacco smoking on lens nucleus by Pentacam HR lens densitometry (LD) in young adults. Prospective cross-sectional case series. Thirty subjects (23 M, 7 F) who were chronic cigarette smokers (≥10 cigarettes/day for at least 2 years) (group 1) and another 30 subjects (23 M, 7 F) who did not smoke (group 2), were included in this study. The patients were matched for age and sex between the groups. The exclusion criteria were any history of ocular surgery, any systemic disorders and any ocular diseases except for mild refractive disorders. Lens densitometry measurements were done with the Pentacam HR (Oculus, Wetzlar, Germany). The Schirmer test and pachymetry measurements were also performed. Mean age of the patients for both groups was 28.90 ± 8.20 years (range: 18-40 years). Mean lens densitometry (LD) measurements of Group 1 (chronic cigarette smoking group) were higher than those of Group 2 (control group) in all LD techniques; however only mean "peak" LD measurements showed a statistically significant difference between these two groups (Group 1: 8.67 ± 0.61, Group 2: 8.44 ± 0.70, p = 0.04). The mean Schirmer test value was 12.43 ± 5.60 mm in Group 1 and 13.00 ± 4.26 mm in Group 2 (p = 0.55). The mean central corneal thickness (CCT) value was 564.23 ± 34.61 µm in Group 1 and 550.47 ± 32.94 µm in Group 2 (p = 0.03). The Pentacam HR LD seems to be an important option for the evaluation of lens nucleus in young adults, because it gives objective and quantitative data. Although chronic smoking increases lens nucleus density in young adults, the effect is not statistically significant when compared with the control group.

  18. Implementation HR information system – part of a unified information environment of MPEI

    Directory of Open Access Journals (Sweden)

    I. M. Krepkov

    2016-01-01

    Full Text Available The article is devoted to the unified information environment of National Research University “Moscow Power Engineering Institute” (MPEI, and its most important component – the HR information system. The article describes the architecture of the unified information space of MPEI. The main objective of the development of the HR information system – to provide access to users, including other information systems, to actual information about employees of MPEI.HR information system are based on many years of operating experience of the previous system and the like, are available on the market today, taking into account the decisions of personnel. The earlier HR information system was developed in 1995–1997 and used until mid-2015. In the process of its using it has accumulated a large number of «patches» and requests for revision that was stopped by limitations in the platform and solutions architecture. Comparative analysis of 1C and SAP products showed that the cost of implementation, configuration and maintenance of these products is higher than developing new solutions. Package of Microsoft technology software was chosen as a platform. These technologies have proven themselves in the development of similar projects, and vendor solutions for a long time support all key processes of information systems. Important is the presence of the selected software Microsoft FSTEC certificates (Federal Service for Technical and Export Control, which support the use of these products for storing and processing information in accordance with the laws of the Russian Federation. The MPEI has already implemented a number of systems on the Microsoft platform – postgraduate register, an Internet portal, etc. The use of technology of one supplier facilitates the integration processes and products into a unified information environment. The article details the technical and hardware specifications of the HR information system. The result of the work on

  19. Mas-allatotropin in the developing antennal lobe of the sphinx moth Manduca sexta: distribution, time course, developmental regulation, and colocalization with other neuropeptides.

    Science.gov (United States)

    Utz, Sandra; Huetteroth, Wolf; Vömel, Matthias; Schachtner, Joachim

    2008-01-01

    The paired antennal lobes (ALs) of the sphinx moth Manduca sexta serve as a well-established model for studying development of the primary integration centers for odor information in the brain. To further reveal the role of neuropeptides during AL development, we have analyzed cellular distribution, developmental time course, and regulation of the neuropeptide M. sexta allatotropin (Mas-AT). On the basis of morphology and appearance during AL formation, seven major types of Mas-AT-immunoreactive (ir) cells could be distinguished. Mas-AT-ir cells are identified as local, projection, and centrifugal neurons, which are either persisting larval or newly added adult-specific neurons. Complementary immunostaining with antisera against two other neuropeptide families (A-type allatostatins, RFamides) revealed colocalization within three of the Mas-AT-ir cell types. On the basis of this neurochemistry, the most prominent type of Mas-AT-ir neurons, the local AT neurons (LATn), could be divided in three subpopulations. The appearance of the Mas-AT-ir cell types occurring during metamorphosis parallels the rising titer of the developmental hormone 20-hydroxyecdysone (20E). Artificially shifting the 20E titer to an earlier developmental time point resulted in the precocious occurrence of Mas-AT immunostaining. This result supports the hypothesis that the pupal rise of 20E is causative for Mas-AT expression during AL development. Comparing localization and developmental time course of Mas-AT and other neuropeptides with the time course of AL formation suggests various functions for these neuropeptides during development, including an involvement in the formation of the olfactory glomeruli.

  20. Genomic tools and and prospects for new breeding techniques in flower bulb crops

    Science.gov (United States)

    For many of the new breeding techniques, sequence information is of the utmost importance. In addition to current breeding techniques, such as marker-assisted selection (MAS) and genetic modification (GM), new breeding techniques such as zinc finger nucleases, oligonucleotide-mediated mutagenesis, R...

  1. NOMEX - a universal diagnostic dosemeter, mA.s, and kV meter for acceotance test measurements and quality assurance

    International Nuclear Information System (INIS)

    Hein, G.; Pychlau, P.; Schuele, E.

    1992-01-01

    A universal diagnostic dosemeter is introduced which was designed for acceptance test measurements and quality assurance. It can also be used for periodic constancy checks. To facilitate the comprehensive tests, the NOMEX can measure all important quantities, such as dose and dose rate, mean peak voltage, exposure time, mA.s product, dose per mA.s, dose per pulse, attenuation factor, relative standard deviation and length dose product in CT. All these quantities, except the mA.s product, are measured non-invasively. The instrument's concept, its applications and technical data are described. (author)

  2. Microstructure and Porosity of Laser-welded Dissimilar Material Joints of HR-2 and J75

    Science.gov (United States)

    Shen, Xianfeng; Teng, Wenhua; Zhao, Shuming; He, Wenpei

    Dissimilar laser welding of HR-2 and J75 has a wide range of applications in high-and low-temperature hydrogen storage. The porosity distributions of the welded joints were investigated at different line energies, penetration status, and welding positions (1G, 2G, and 3G). The effect of the welding position on the welding appearance was evident only at high line energies because of the essential effect of gravity of the larger and longer dwelling molten pool. The porosity of the welded joints between the solutionised and aged J75 and HR-2 at the 3G position and partial penetration was located at the weld centre line, while the porosity at the 2G position with full penetration was distributed at the weld edges, which is consistent with the distribution of floating slag. Full keyhole penetration resulted in minimum porosity, partial penetration resulted in moderate porosity, and periodic molten pool penetration resulted in maximum porosity.

  3. hrHPV E5 oncoprotein: immune evasion and related immunotherapies.

    Science.gov (United States)

    de Freitas, Antonio Carlos; de Oliveira, Talita Helena Araújo; Barros, Marconi Rego; Venuti, Aldo

    2017-05-25

    The immune response is a key factor in the fight against HPV infection and related cancers, and thus, HPV is able to promote immune evasion through the expression of oncogenes. In particular, the E5 oncogene is responsible for modulation of several immune mechanisms, including antigen presentation and inflammatory pathways. Moreover, E5 was suggested as a promising therapeutic target, since there is still no effective medical therapy for the treatment of HPV-related pre-neoplasia and cancer. Indeed, several studies have shown good prospective for E5 immunotherapy, suggesting that it could be applied for the treatment of pre-cancerous lesions. Thus, insofar as the majority of cervical, oropharyngeal and anal cancers are caused by high-risk HPV (hrHPV), mainly by HPV16, the aim of this review is to discuss the immune pathways interfered by E5 oncoprotein of hrHPV highlighting the various aspects of the potential immunotherapeutic approaches.

  4. Repeatability of central corneal thickness measurement with the Pentacam HR system

    Directory of Open Access Journals (Sweden)

    Ruiz Simonato Alonso

    2012-02-01

    Full Text Available PURPOSE: To assess the repeatability of central corneal thickness measurement at the geometrical center (Central Corneal Thickness - CCT given by the Pentacam High Resolution (HR Comprehensive Eye Scanner (Oculus, Wetzlar, Germany over time. METHODS: Prospective, single center, observational study. Two separate CCT measurements were taken by the Pentacam corneal tomography exam (CTm 3 to 12 months apart, and compared. RESULTS: One hundred and sixteen eyes (n=116 of 62 health patients were included in this study. Average CCT in first and last visits was 541.6±37 µm and 543.6±36.9 µm respectively. Mean difference between both measurements was 9.2±6.4 µm, and there was no statistically significant difference in CCT measurement between visits, with good correlation between them (P = 0.057, r² = 0,9209. CONCLUSION: Pentacam (HR CTm gives repeatable CCT measurements over time.

  5. Interface characteristic during bonding of Be and HR-1 stainless steel by hot pressing

    International Nuclear Information System (INIS)

    Li Hui; Kang Renmu; Zhou Shangqi; Kong Jilan; Zhang Pengcheng

    2010-01-01

    Be and HR-I stainless steel was diffusion bonded by hot pressing. The microstructure,composition and phase distribution and mechanical properties of the joints were analyzed using the optical microscopy, scanning electron microscopy(SEM), scanning auger microspectroscopy(SAM) and x-ray diffraction(XRD), and the effect of different interlayer materials Cu and Al and Ag-Cu alloy was also discussed. The results show that it is not easy to joint Be and HR-1 stainless when Al was used as the interlayer material, but good joints can be obtained using Cu and Ag and Cu alloy as the interlayer materials, because the formation of Be-Fe brittle intermetallic compounds was prevented. Ag-Cu alloy is the best interlayer materials among them, as it can reduce the mutual diffusion between Be and Fe. (authors)

  6. Redesain Pasar Pagi Jalan HR. Soebrantas Pekanbaru dengan Pendekatan Arsitektur Tropis

    OpenAIRE

    ', Asmadi '; Hidayat, Wahyu '; Rijal, Muhammad '

    2014-01-01

    Pasar Pagi located in HR.Soebrantas street takes an imfortant role in fulfilling the needs of the society surroundings, completely to the economic social order. Considering the unsuppported services faced in these public facilities; frequently traffic congestion, insufficient parking space, poor drainage system, and incompletely arranged market spot, redesigning of the Pasar Pagi is a significance to overcome the cases exist. The design method undertaken prior to the project uses the principl...

  7. HR TRAINING PROGRAMS – CASE STUDY: WHAT ARE THE PARTICIPANTS’ EXPECTATIONS?

    OpenAIRE

    Abrudan Maria-Madela; Hatos Roxana; Matei Mirabela-Constanta

    2010-01-01

    When conducting a training program, training providers should ask themselves this question: What are the participants’ expectations? Training providers must correlate their programs with the needs and expectations of participants in order to be successful. Considering there is a need for the professionalization of human resources management activities, we focused our attention on three key occupations of HR: Human Resources Analyst, Human Resources Inspector and Human Resources Manager. To as...

  8. Limited field investigation report for the 100-HR-2 Operable Unit

    International Nuclear Information System (INIS)

    1994-09-01

    This report summarizes the data collection and analysis activities conducted during the 100-HR-2 Operable Unit investigative phase and the associated qualitative risk assessment (QRA). The 100-HR-2 Operable Unit contains solid waste burial grounds, an ash pit, bum pits, electrical facilities, septic systems, and support facilities. All known and suspected areas of contamination were classified as solid waste burial grounds or low-priority waste sites based on the collective knowledge of the operable unit managers (representatives from the US Department of Energy [DOE], the US Environmental Protection Agency [EPA], and Washington Department of Ecology [Ecology]) during the preparation of the 100-HR-2 Operable Unit work plan (DOE/RL 1993f). Solid waste burial grounds were judged to pose sufficient risk(s), through one or more pathways, to require evaluation for an interim remedial measure (IRM) as per the Hanford Past-Practice Strategy (HPPS) (DOE/RL 1991) and negotiations with DOE, EPA, and Ecology. An IRM is intended to achieve remedies that are likely to lead to a final record of decision. Low-priority sites are those judged not to pose significant risk to require the streamlined evaluation. There were six low-priority waste sites and seven solid waste burial grounds identified. The investigative phase was conducted in accordance with the RCRA Facility Investigation/Corrective Measures Study Work Plan for the 100-HR-2 Operable Unit (DOE/RL 1993f). The QRA was performed in accordance with the Hanford Site Baseline Risk Assessment Methodology (DOE/RL 1993b) and the recommendations incorporate the strategies of the HPPS. The purpose of this report is to: (1) provide a summary of site investigative activities; (2) refine the conceptual exposure model (as needed); (3) identify chemical- and location-specific corrective action requirements; and (4) provide a human health and ecological QRA associated with solid waste burial grounds

  9. Family responsibilities discrimination, HR work-family discourse and organizational mediation of US civil rights law

    OpenAIRE

    Robin, Stryker; Heidi, Reynolds-Stenson; Krista, Frederico

    2017-01-01

    Because the US addresses work-family concerns mostly through voluntary employer-provided benefits combined with anti-discrimination legislation, organizational mediation of law shapes the content and impact of employ-ers’ response to employees’ work- family issues. Centrality of organiza-tional mediation means centrality of HR professional discourse. Given skyrocketing lawsuits claiming family responsibilities discrimination (FRD), we examine FRD-related discourse, 1980-2012, in the two high...

  10. The high resolution optical instruments for the Pleiades HR Earth observation satellites

    Science.gov (United States)

    Gaudin-Delrieu, Catherine; Lamard, Jean-Luc; Cheroutre, Philippe; Bailly, Bruno; Dhuicq, Pierre; Puig, Olivier

    2017-11-01

    Coming after the SPOT satellites series, PLEIADESHR is a CNES optical high resolution satellite dedicated to Earth observation, part of a larger optical and radar multi-sensors system, ORFEO, which is developed in cooperation between France and Italy for dual Civilian and Defense use. The development of the two PLEIADES-HR cameras was entrusted by CNES to Thales Alenia Space. This new generation of instrument represents a breakthrough in comparison with the previous SPOT instruments owing to a significant step in on-ground resolution, which approaches the capabilities of aerial photography. The PLEIADES-HR instrument program benefits from Thales Alenia Space long and successful heritage in Earth observation from space. The proposed solution benefits from an extensive use of existing products, Cannes Space Optics Centre facilities, unique in Europe, dedicated to High Resolution instruments. The optical camera provides wide field panchromatic images supplemented by 4 multispectral channels with narrow spectral bands. The optical concept is based on a four mirrors Korsch telescope. Crucial improvements in detector technology, optical fabrication and electronics make it possible for the PLEIADES-HR instrument to achieve the image quality requirements while respecting the drastic limitations of mass and volume imposed by the satellite agility needs and small launchers compatibility. The two flight telescopes were integrated, aligned and tested. After the integration phase, the alignment, mainly based on interferometric measurements in vacuum chamber, was successfully achieved within high accuracy requirements. The wave front measurements show outstanding performances, confirmed, after the integration of the PFM Detection Unit, by MTF measurements on the Proto-Flight Model Instrument. Delivery of the proto flight model occurred mi-2008. The FM2 Instrument delivery is planned Q2-2009. The first optical satellite launch of the PLEIADES-HR constellation is foreseen

  11. Data validation report for the 100-HR-3 Operable Unit, fifth round groundwater samples

    International Nuclear Information System (INIS)

    Vukelich, S.E.

    1994-01-01

    The data from the chemical analysis of 68 samples from the 100-HR-3 Operable Unit Third Quarter 1993 Groundwater Sampling Investigation and their related quality assurance samples were reviewed and validated to verify that reported sample results were of sufficient quality to support decisions regarding remedial actions performed at the site. Sample analysis included inorganics and general chemical parameters. Fifty three samples were validated for radiochemical parameters

  12. Monitoring training status with HR measures: do all roads lead to Rome?

    Directory of Open Access Journals (Sweden)

    Martin eBuchheit

    2014-02-01

    Full Text Available Monitoring an athlete's physiological status in response to various types and volumes of (aerobic-oriented training can provide useful information for optimizing training programs. Measures of resting, exercise and recovery heart rate (HR are receiving increasing interest for monitoring fatigue, fitness and endurance performance responses, which has direct implications for adjusting training load 1 daily during specific training blocks and 2 throughout the competitive season. These measures are still not widely implemented to monitor athletes’ responses to training load, probably because of apparent contradictory findings in the literature. In this review I contend that most of the contradictory findings are related to methodological inconsistencies and/or misinterpretation of the data rather than to limitations of heart rate measures to accurately inform on training status. I also provide evidence that measures derived from 5-min (almost daily recordings of resting (indices capturing beat-to-beat changes in HR, reflecting parasympathetic activity and submaximal exercise (30- to 60-s average HR are likely the most useful monitoring tools. For appropriate interpretation at the individual level, changes in a given measure should be interpreted by taking into account the error of measurement and the smallest important change of the measure, as well as the training context (training phase, load and intensity distribution. The decision to use a given measure should be based upon the level of information that is required by the athlete, the marker’s sensitivity to changes in training status and the practical constrains required for the measurements. However, measures of HR cannot inform on all aspects of wellness, fatigue and performance, so their use in combination with daily training logs, psychometric questionnaires and non-invasive, cost-effective performance tests such as a countermovement jump may offer a complete solution to monitor

  13. Remote Sensing of Radiative and Microphysical Properties of Clouds During TC (sup 4): Results from MAS, MASTER, MODIS, and MISR

    Science.gov (United States)

    King, Michael D.; Platnick, Steven; Wind, Galina; Arnold, G. Thomas; Dominguez, Roseanne T.

    2010-01-01

    The Moderate Resolution Imaging Spectroradiometer (MODIS) Airborne Simulator (MAS) and MODIS/Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) Airborne Simulator (MASTER) were used to obtain measurements of the bidirectional reflectance and brightness temperature of clouds at 50 discrete wavelengths between 0.47 and 14.2 microns (12.9 microns for MASTER). These observations were obtained from the NASA ER-2 aircraft as part of the Tropical Composition, Cloud and Climate Coupling (TC4) experiment conducted over Central America and surrounding Pacific and Atlantic Oceans between 17 July and 8 August 2007. Multispectral images in eleven distinct bands were used to derive a confidence in clear sky (or alternatively the probability Of cloud) over land and ocean ecosystems. Based on the results of individual tests run as part of the cloud mask, an algorithm was developed to estimate the phase of the clouds (liquid water, ice, or undetermined phase). The cloud optical thickness and effective radius were derived for both liquid water and ice clouds that were detected during each flight, using a nearly identical algorithm to that implemented operationally to process MODIS Cloud data from the Aqua and Terra satellites (Collection 5). This analysis shows that the cloud mask developed for operational use on MODIS, and tested using MAS and MASTER data in TC(sup 4), is quite capable of distinguishing both liquid water and ice clouds during daytime conditions over both land and ocean. The cloud optical thickness and effective radius retrievals use five distinct bands of the MAS (or MASTER), and these results were compared with nearly simultaneous retrievals of marine liquid water clouds from MODIS on the Terra spacecraft. Finally, this MODIS-based algorithm was adapted to Multiangle Imaging SpectroRadiometer (MISR) data to infer the cloud optical thickness Of liquid water clouds from MISR. Results of this analysis are compared and contrasted.

  14. Examination of the fine interstitial changes of pneumoconiosis with high resolution computed tomography (HR-CT)

    International Nuclear Information System (INIS)

    Kido, Masamitsu; Miyazaki, Nobuyoshi; Harada, Susumu; Nakata, Hajime

    1986-01-01

    High resolution CT was performed in 14 patients with fine interstitial changes of pneumoconiosis and Review image was evaluated for the diagnostic accuracy as compared with conventional chest roentgenogram. Of the 14 Patients in the study, 7 were divided category 1 by the ILO U/C classification, 4 were category 2, 3 were category 3. Studies of lung function showed obstructive ventilatory disturbance characterized by moderate reduction in FEV 1.0% (58.6 ± 16.5 %) and V25/H (0.34 ± 0.24 l/sec/m). HR-CT defined more sensitive in the presence of fine lung nodules than conventional X-p, and showed high contrast interfaces provided by the aerated lung. HR-CT was also of value in detecting bulla, bleb, peripleural changes and hilar lymphadenopathy. Radiologic-pathologic correlation was examined on tne specimens of transbronchial lung biopsy in 4 patients, and revealed the diagnostic usefullness of HR-CT. (author)

  15. P/2006 HR30 (Siding Spring): A Low-activity Comet in Near-Earth Space

    Science.gov (United States)

    Hicks, Michael D.; Bauer, James M.

    2007-01-01

    The low cometary activity of P/2006 HR30 (Siding Spring) allowed a unique opportunity to study the nucleus of a periodic comet while near perihelion. P/2006 HR30 was originally targeted as a potential extinct comet, and we measured spectral reflectance and dust production using long-slit CCD spectroscopy and wide-field imaging obtained at the Palomar Mountain 200 inch telescope on 2006 August 3 and 4. The dust production Afp = 19.7 +/- 0.4 cm and mass-loss rate Q(dust) 4.1 +/- 0.1 kg/sec of the comet were approximately 2 orders of magnitude dust less than 1P/Halley at similar heliocentric distance. The VRI colors derived from the spectral reflectance were compared to Kuiper Belt objects, Centaurs, and other cometary nuclei. We found that the spectrum of P/2006 HR30 was consistent with other comets. However, the outer solar system bodies have a color distribution statistically distinct from cometary nuclei. It is our conjecture that cometary activity, most likely the reaccretion of ejected cometary dust, tends to moderate and mute the visible colors of the surface of cometary nuclei.

  16. A Qualitative Study of HR/OHS Stress Interventions in Australian Universities.

    Science.gov (United States)

    Pignata, Silvia; Winefield, Anthony H; Boyd, Carolyn M; Provis, Chris

    2018-01-09

    To enhance the understanding of psychosocial factors and extend research on work stress interventions, we investigated the key human resource (HR)/occupational health and safety (OHS) stress interventions implemented at five Australian universities over a three-year period. Five senior HR Directors completed an online survey to identify the intervention strategies taken at their university in order to reduce stress and enhance employee well-being and morale. We also explored the types of individual-, organization-, and individual/organization-directed interventions that were implemented, and the strategies that were prioritized at each university. Across universities, the dominant interventions were strategies that aimed to balance the social exchange in the work contract between employee-organization with an emphasis on initiatives to: enhance training, career development and promotional opportunities; improve remuneration and recognition practices; and to enhance the fairness of organizational policies and procedures. Strategies to improve work-life balance were also prominent. The interventions implemented were predominantly proactive (primary) strategies focused at the organizational level and aimed at eliminating or reducing or altering work stressors. The findings contribute to the improved management of people at work by identifying university-specific HR/OHS initiatives, specifically leadership development and management skills programs which were identified as priorities at three universities.

  17. A Qualitative Study of HR/OHS Stress Interventions in Australian Universities

    Directory of Open Access Journals (Sweden)

    Silvia Pignata

    2018-01-01

    Full Text Available To enhance the understanding of psychosocial factors and extend research on work stress interventions, we investigated the key human resource (HR/occupational health and safety (OHS stress interventions implemented at five Australian universities over a three-year period. Five senior HR Directors completed an online survey to identify the intervention strategies taken at their university in order to reduce stress and enhance employee well-being and morale. We also explored the types of individual-, organization-, and individual/organization-directed interventions that were implemented, and the strategies that were prioritized at each university. Across universities, the dominant interventions were strategies that aimed to balance the social exchange in the work contract between employee-organization with an emphasis on initiatives to: enhance training, career development and promotional opportunities; improve remuneration and recognition practices; and to enhance the fairness of organizational policies and procedures. Strategies to improve work-life balance were also prominent. The interventions implemented were predominantly proactive (primary strategies focused at the organizational level and aimed at eliminating or reducing or altering work stressors. The findings contribute to the improved management of people at work by identifying university-specific HR/OHS initiatives, specifically leadership development and management skills programs which were identified as priorities at three universities.

  18. A Qualitative Study of HR/OHS Stress Interventions in Australian Universities

    Science.gov (United States)

    Winefield, Anthony H.; Boyd, Carolyn M.

    2018-01-01

    To enhance the understanding of psychosocial factors and extend research on work stress interventions, we investigated the key human resource (HR)/occupational health and safety (OHS) stress interventions implemented at five Australian universities over a three-year period. Five senior HR Directors completed an online survey to identify the intervention strategies taken at their university in order to reduce stress and enhance employee well-being and morale. We also explored the types of individual-, organization-, and individual/organization-directed interventions that were implemented, and the strategies that were prioritized at each university. Across universities, the dominant interventions were strategies that aimed to balance the social exchange in the work contract between employee-organization with an emphasis on initiatives to: enhance training, career development and promotional opportunities; improve remuneration and recognition practices; and to enhance the fairness of organizational policies and procedures. Strategies to improve work-life balance were also prominent. The interventions implemented were predominantly proactive (primary) strategies focused at the organizational level and aimed at eliminating or reducing or altering work stressors. The findings contribute to the improved management of people at work by identifying university-specific HR/OHS initiatives, specifically leadership development and management skills programs which were identified as priorities at three universities. PMID:29315278

  19. Statistical HR diagrams for one hundred and fifteen thousand proper-motion stars

    International Nuclear Information System (INIS)

    Luyten, W.J.

    1978-01-01

    Since regular HR diagrams require apparent magnitudes, colors or spectra, and parallaxes, and such complete data are available for relatively few stars, there may be some advantage in making up diagrams which utilize proper motions instead of parallaxes, and are thus statistically similar to an HR diagram. The reduced proper motion, first used by Hertzsprung, is defined as H=m+5+5log μ, but may also be written as H=M+5log T, where T is the tangential velocity, and is expressed in astronomical units per year. A diagram plotting H against color will thus contain the considerable dispersion in tangential velocity which is a serious disadvantage. However, this is outweighed by two practical advantages. First, the one and the same person who does the proper motion survey can, and does also determine the other two quantities needed. Second, when using data obtained from such a proper motion survey one deals, statistically, with all the stars within a given distance and the results, therefore, are much more representative of the real situation in space than many HR diagrams which often contain an unrealistic preponderance of giants. (Auth.)

  20. 27Al Magic Angle Spinning–Nuclear Magnetic Resonance (MAS-NMR) Analyses Applied to Historical Mortars

    Czech Academy of Sciences Publication Activity Database

    Hanzlíček, Tomáš; Perná, Ivana; Brus, Jiří

    2013-01-01

    Roč. 7, č. 2 (2013), s. 153-164 ISSN 1558-3058 R&D Projects: GA AV ČR IAA300460702 Institutional research plan: CEZ:AV0Z30460519; CEZ:AV0Z40500505 Keywords : mortars * magic angle spinning –nuclear magnetic resonance (MAS-NMR) in solid state * alumina-silicates Subject RIV: DM - Solid Waste and Recycling Impact factor: 0.714, year: 2013 http://www.tandfonline.com/doi/abs/10.1080/15583058.2011.624253

  1. Pharmacological significance of the interplay between angiotensin receptors: MAS receptors as putative final mediators of the effects elicited by angiotensin AT1 receptors antagonists.

    Science.gov (United States)

    Pernomian, Larissa; Pernomian, Laena; Gomes, Mayara S; da Silva, Carlos H T P

    2015-12-15

    The interplay between angiotensin AT1 receptors and MAS receptors relies on several inward regulatory mechanisms from renin-angiotensin system (RAS) including the functional crosstalk between angiotensin II and angiotensin-(1-7), the competitive AT1 antagonism exhibited by angiotensin-(1-7), the antagonist feature assigned to AT1/MAS heterodimerization on AT1 signaling and the AT1-mediated downregulation of angiotensin-converting enzyme 2 (ACE2). Recently, such interplay has acquired an important significance to RAS Pharmacology since a few studies have supporting strong evidences that MAS receptors mediate the effects elicited by AT1 antagonists. The present Perspective provides an overview of the regulatory mechanisms involving AT1 and MAS receptors, their significance to RAS Pharmacology and the future directions on the interplay between angiotensin receptors. Copyright © 2015 Elsevier B.V. All rights reserved.

  2. Intelligent business processes composition based on mas, semantic and cloud integration (IPCASCI)

    OpenAIRE

    García Coria, José Alberto

    2014-01-01

    [EN]Component reuse is one of the techniques that most clearly contributes to the evolution of the software industry by providing efficient mechanisms to create quality software. Reuse increases both software reliability, due to the fact that it uses previously tested software components, and development productivity, and leads to a clear reduction in cost. Web services have become are an standard for application development on cloud computing environments and are essential ...

  3. Microscopic structural analysis of fractured silk fibers from Bombyx mori and Samia cynthia ricini using 13C CP/MAS NMR with a 1 mm microcoil MAS NMR probehead

    KAUST Repository

    Yamauchi, Kazuo

    2010-07-01

    Conformational changes have been studied in silk fibers from the domestic silkworm Bombyx mori and a wild silkworm Samia cynthia ricini as a result of fractured by stretching. About 300 samples consisting of only the fractured regions of [1-13C]Ala or [1-13C]Gly labeled silk fibers were collected and observed by 13C CP/MAS NMR spectra. The total amount of these fractured fibers is only about 1 mg and therefore we used a home-built 1 mm microcoil MAS NMR probehead. A very small increase in the fraction of random coil was noted for the alanine regions of both silk fibroins and for the glycine region of B. mori silk fibroin. However, there is no difference in the spectra before and after fractured for the glycine region of S. c. ricini silk fibroin. Thus, the influence of fracture occurs exclusively at the Ala region for S. c. ricini. The relationship between sequence, fracture and structure is discussed. © 2010 Elsevier Inc. All rights reserved.

  4. Determination of the structural changes by Raman and {sup 13}C CP/MAS NMR spectroscopy on native corn starch with plasticizers

    Energy Technology Data Exchange (ETDEWEB)

    Cozar, O. [Academy of Romanian Scientists, Splaiul Independentei 54, 050094, Bucharest, Romania and National Institute of Research-Development for Machines and Installations Designed to Agriculture and Food Industry - INMA Bucureşti - Cluj-Napoca Branch (Romania); Filip, C.; Tripon, C. [National Institute for Research and Development of Isotopic and Molecular Technologies, 65-103 Donath, 400293 Cluj-Napoca (Romania); Cioica, N.; Coţa, C.; Nagy, E. M. [National Institute of Research-Development for Machines and Installations Designed to Agriculture and Food Industry - INMA Bucureşti - Cluj-Napoca Branch, RO-400458 Cluj-Napoca (Romania)

    2013-11-13

    The plasticizing - antiplasticizing effect of water and glycerol contents on native corn starch samples is investigated by FT-Raman and {sup 13}C CP/MAS NMR spectroscopy. The presence of both amorphous and crystalline structural phases was evidenced in pure native corn starch and also in the samples containing plasticizers. Among the crystalline starch structures, the A- and V- types were suggested by CP/MAS NMR spectra.

  5. Effects of Cornus mas L. and Morus rubra L. extracts on penicillin-induced epileptiform activity: an electrophysiological and biochemical study.

    Science.gov (United States)

    Tubaş, Filiz; Per, Sedat; Taşdemir, Abdulkadir; Bayram, Ayşe Kaçar; Yıldırım, Mehmet; Uzun, Aydın; Saraymen, Recep; Gümüş, Hakan; Elmalı, Ferhan; Per, Hüseyin

    2017-01-01

    Traditionally, Morus rubra L. (Moraceae) (red mulberry) and Cornus mas L. (Cornacea) (cornelian cherry) fruits are eaten fresh and are also used in marmalades, juices, jam, natural dyes in Turkey and are believed to have beneficial effects in case of multiple health issues such as antipyretic, diarrhea and intestinal parasites. However, the effects of M. rubra and C. mas on epilepsy has not been known. This study evaluates the effects of M. rubra and C. mas extracts on penicillin-induced epileptiform activity. Sixty Wistar rats randomly divided into ten groups (n=6): control, sham, penicillin, penicillin+M. rubra extract (2.5, 5, 10, 20 mg/kg) and penicillin+C. mas extract (2.5, 5, 10 mg/kg). Epileptiform activity was induced by using penicillin (500 IU, i.c.) and electrocorticogram records (150 min) were obtained. Also, biochemical analysis in blood samples were evaluated. According to the electrocorticogram analysis, the effective dose was detected as 10 mg/kg for both C. mas and M. rubra. This dose decreased the spike frequencies of convulsions while amplitude wasn't changed by both substances. In erythrocyte studies, there were significant differences regarding nitric oxide in the control, sham and penicillin groups. There were significant differences regarding malondialdehyde in all groups. In the plasma, there were significant differences among groups regarding xanthine oxidase in the penicillin‑C. mas and penicillin‑M. rubra groups. There were differences regarding malondialdehyde in the penicillin-C. mas and M. rubra-C. mas groups. Both extracts reduced the frequency of epileptiform activity. After administration of the extracts malondialdehyde levels decreased also in both erythrocytes and plasma.

  6. Design criteria and design basis for the 100-HR-3 and 100-KR-4 pump-and-treat projects

    International Nuclear Information System (INIS)

    McKinley, W.S.; Winters, J.N.

    1996-06-01

    The 100-HR-3 and 100-KR-4 Operable Units are located in the 100 Area at the Hanford Site in Richland, Washington. The document describes the project objectives and design criteria to be used for the 100-HR-3 and 100-KR-4 groundwater pump-and-treat design activities

  7. The more the better…or is it? The contradictory effects of HR practices on knowledge sharing motivation and behavior

    NARCIS (Netherlands)

    Andreeva, T.; Sergeeva, A.

    2016-01-01

    This article examines how individual-level antecedents such as motivation and ability to share knowledge mediate the relationship between HR practices and knowledge-sharing behaviour. The results of a survey of 329 secondary school teachers reveal the contradictory effects of different HR practices

  8. Understanding the effectiveness of precursor reductions in lowering 8-hr ozone concentrations--Part II. The eastern United States.

    Science.gov (United States)

    Reynolds, Steven D; Blanchard, Charles L; Ziman, Stephen D

    2004-11-01

    Analyses of ozone (O3) measurements in conjunction with photochemical modeling were used to assess the feasibility of attaining the federal 8-hr O3 standard in the eastern United States. Various combinations of volatile organic compound (VOC) and oxides of nitrogen (NOx) emission reductions were effective in lowering modeled peak 1-hr O3 concentrations. VOC emissions reductions alone had only a modest impact on modeled peak 8-hr O3 concentrations. Anthropogenic NOx emissions reductions of 46-86% of 1996 base case values were needed to reach the level of the 8-hr standard in some areas. As NOx emissions are reduced, O3 production efficiency increases, which accounts for the less than proportional response of calculated 8-hr O3 levels. Such increases in O3 production efficiency also were noted in previous modeling work for central California. O3 production in some urban core areas, such as New York City and Chicago, IL, was found to be VOC-limited. In these areas, moderate NOx emissions reductions may be accompanied by increases in peak 8-hr O3 levels. The findings help to explain differences in historical trends in 1- and 8-hr O3 levels and have serious implications for the feasibility of attaining the 8-hr O3 standard in several areas of the eastern United States.

  9. The gap between research and practice: a replication study on the HR professionals' beliefs about effective human resource practices

    NARCIS (Netherlands)

    Sanders, Karin; van Riemsdijk, Maarten; Groen, B.A.C.

    2008-01-01

    In 2002 Rynes, Colbert and Brown asked human resource (HR) professionals to what extent they agreed with various HR research findings. Responses from 959 American participants showed that there are large discrepancies between research findings and practitioners' beliefs about effective human

  10. Classification of astrocyto-mas and meningiomas using statistical discriminant analysis on MRI data

    International Nuclear Information System (INIS)

    Siromoney, Anna; Prasad, G.N.S.; Raghuram, Lakshminarayan; Korah, Ipeson; Siromoney, Arul; Chandrasekaran, R.

    2001-01-01

    The objective of this study was to investigate the usefulness of Multivariate Discriminant Analysis for classifying two groups of primary brain tumours, astrocytomas and meningiomas, from Magnetic Resonance Images. Discriminant analysis is a multivariate technique concerned with separating distinct sets of objects and with allocating new objects to previously defined groups. Allocation or classification rules are usually developed from learning examples in a supervised learning environment. Data from signal intensity measurements in the multiple scan performed on each patient in routine clinical scanning was analysed using Fisher's Classification, which is one method of discriminant analysis

  11. Medical Imaging Teacher: A program to simulate X-ray images of the body by considering kVp, mAs and FFD values

    Directory of Open Access Journals (Sweden)

    Umit Kara

    2017-06-01

    Full Text Available Introduction: Teaching styles and methods have been constantly changing in the recent years. In the 1980s and 90s, the world was introduced to various developed devices, such as smart boards and early generation smart phones that had an immediate innovative effect on education. These advancements has resulted in a considerable improvement in the current educational techniques. The innovations in medical techniques and their quality is of paramount importance. The aim of this study was to provide an innovative and useful software on radiological applications and contribute to the related literature. Materials and Methods: The Medical Imaging Teacher (MIT program was created and the prototype application was implemented on the Android platform for free use. The programing and testing of the usability of the application were performed by the users of the Google Play Store. Results: In this program, we have developed new software to simulate the X-ray images of the body by considering the peak kilovoltage (kVp, milliamperage per second (mAs, and film focus distance (FFD values. The application has been downloaded more than 1,000 times without paid advertising. We enrolled 131 participants, who made comments and gave 4.8 points on average. Conclusion: It can be concluded that with innovative digital programs, such as the MIT, the medical machine-based learning and medical applications have risen to new levels. The software on medical testing and examination is gaining increasing popularity among the health-related applications for smart phones.

  12. Brain angiotensin-(1-7)/Mas axis: A new target to reduce the cardiovascular risk to emotional stress.

    Science.gov (United States)

    Fontes, Marco Antônio Peliky; Martins Lima, Augusto; Santos, Robson Augusto Souza dos

    2016-04-01

    Emotional stress is now considered a risk factor for several diseases including cardiac arrhythmias and hypertension. It is well known that the activation of neuroendocrine and autonomic mechanisms features the response to emotional stress. However, its link to cardiovascular diseases and the regulatory mechanisms involved remain to be further comprehended. The renin-angiotensin system (RAS) plays an important role in homeostasis on all body systems. Specifically in the brain, the RAS regulates a number of physiological aspects. Recent data indicate that the activation of angiotensin-converting enzyme/angiotensin II/AT1 receptor axis facilitates the emotional stress responses. On the other hand, growing evidence indicates that its counterregulatory axis, the angiotensin-converting enzyme 2 (ACE2)/(Ang)iotensin-(1-7)/Mas axis, reduces anxiety and attenuates the physiological responses to emotional stress. The present review focuses on angiotensin-(1-7)/Mas axis as a promising target to attenuate the physiological response to emotional stress reducing the risk of cardiovascular diseases. Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. Productivity differences and food security: a metafrontier analysis of rain-fed maize farmers in MasAgro in Mexico

    Directory of Open Access Journals (Sweden)

    M. Laura Donnet

    2017-04-01

    Full Text Available Rain-fed maize production in Mexico includes approximately 6 million hectares which variation in productivity represents huge challenges to meeting the sustainable intensification goals of the Sustainable Modernization of Traditional Agriculture (MasAgro program. We use the information available from farmers participating in this program to investigate the differences in productivity and the effects of the promoted practices and technologies in seven defined rain-fed maize regions. We do this by applying metafrontier analysis to measure the technical efficiency and the technology gap. The results show a range of technical efficiency from 70 to 100%, which indicates the gains that can be achieved through improved management of the current inputs and practices of farmers in the program, and a range of the environment–technology gap between 32 and 82%, which indicates the limitations of the production environment which would require innovations in technologies and policies particularly adapted for the dry, the tropical and the more traditional regions. Furthermore, the results show that the use of hybrid seed and selling into maize markets have the largest impact in increasing maize yields in all regions. The difference between the MasAgro farmers and the average farmers in each region suggest that scaling the project will contribute to increasing maize production and Mexico’s food self-sufficiency.

  14. Minho Affective Sentences (MAS): Probing the roles of sex, mood, and empathy in affective ratings of verbal stimuli.

    Science.gov (United States)

    Pinheiro, Ana P; Dias, Marcelo; Pedrosa, João; Soares, Ana P

    2017-04-01

    During social communication, words and sentences play a critical role in the expression of emotional meaning. The Minho Affective Sentences (MAS) were developed to respond to the lack of a standardized sentence battery with normative affective ratings: 192 neutral, positive, and negative declarative sentences were strictly controlled for psycholinguistic variables such as numbers of words and letters and per-million word frequency. The sentences were designed to represent examples of each of the five basic emotions (anger, sadness, disgust, fear, and happiness) and of neutral situations. These sentences were presented to 536 participants who rated the stimuli using both dimensional and categorical measures of emotions. Sex differences were also explored. Additionally, we probed how personality, empathy, and mood from a subset of 40 participants modulated the affective ratings. Our results confirmed that the MAS affective norms are valid measures to guide the selection of stimuli for experimental studies of emotion. The combination of dimensional and categorical ratings provided a more fine-grained characterization of the affective properties of the sentences. Moreover, the affective ratings of positive and negative sentences were not only modulated by participants' sex, but also by individual differences in empathy and mood state. Together, our results indicate that, in their quest to reveal the neurofunctional underpinnings of verbal emotional processing, researchers should consider not only the role of sex, but also of interindividual differences in empathy and mood states, in responses to the emotional meaning of sentences.

  15. Surface Characterization of Some Novel Bonded Phase Packing Materials for HPLC Columns Using MAS-NMR Spectroscopy

    Directory of Open Access Journals (Sweden)

    Jude Abia

    2015-03-01

    Full Text Available Information on the surface properties of three novel chemically bonded phase packing materials for High performance liquid chromatography (HPLC were obtained using spectra obtained by solid state cross-polarization (CP magic-angle spinning (MAS nuclear magnetic resonance (NMR spectroscopic experiments for the 29Si, and 13C nuclei. These packing materials were: Cogent bidentate C18 bonded to type-C silica, hybrid packing materials XTerra MS C18, and XBridge Prep. C18. The spectra obtained using cross-polarization magic angle spinning (CP-MAS on the Cogent bidentate C18 bonded to type-C silica show the surface to be densely populated with hydride groups (Si-H, with a relative surface coverage exceeding 80%. The hybrid packing materials XTerra and XBridge gave spectra that reveal the silicon atoms to be bonded to organic moieties embedded in the molecular structure of these materials with over 90% of the alkyl silicon atoms found within the completely condensed silicon environments. The hydrolytic stability of these materials were investigated in acidic aqueous solutions at pHs of 7.0 and 3.0, and it was found that while the samples of XTerra and XBridge were not affected by hydrolysis at this pH range, the sample of Cogent lost a significant proportion of its Si-H groups after five days of treatment in acidic aqueous solution.

  16. Klientu attiecību pārvaldības sistēmas izveide autoservisam

    OpenAIRE

    Jaunzems, Ģirts

    2012-01-01

    Diplomdarba tēma ir Klientu attiecību pārvaldības sistēmas izveide autoservisam. Tā mērķis ir izstrādāt un ieviest pielāgotu klientu attiecību pārvaldības sistēmu nelielam autoservisam, tādējādi atvieglojot klientu un viņu darbības vēstures uzskaiti. Lai sasniegtu diplomdarba mērķi, darba autors izpētīja teorētiskos informācijas avotus, salīdzināja divas klientu pārvaldības sistēmas, kā arī izstrādāja sistēmu konkrētam uzņēmumam, veicot arī tās izmaksu analīzi. Diplomdarbā ir secināts, ...

  17. Perilaku Alturisme Karyawan (Studi Kasus pada Mandor Perkebunan Sawit Perseroan Terbatas (PT.Tribuana Mas Kabupaten Tapin

    Directory of Open Access Journals (Sweden)

    Asty Wulandari

    2017-11-01

    Full Text Available One of the tasks of developing into adulthood is to work to meet the needs of his life. Technological advances, materialism, hedonism and the demands of the post-industrial society's needs make some people work brutally for what they want to be fulfilled. Even people are apathetic to the surrounding environment. Nevertheless, there are still a handful of employees who care about their environmental conditions by behaving altruism as happened in PT.Tribuana Mas (TBM. The purpose of this study is to describe employee altruism behavior and explore the factors that encourage employees to behave altruism. The results of the research on 3 employees of PT.Tribuana Mas plantation, Afdeling Juliet conducted qualitatively (nonparticipant observation and in-depth interview, altruism behavioral components are mostly the same, that is behaving helpfully, considering the rights and welfare of others, sharing and honesty. While the different components are seen from the behavior of donating & generosity and Cooperation. Components of altruism behavior reflected on the employees are also in accordance with the teachings of Islam, the namely charity with the foundation of god (ikhlas and there are still nuanced humanity. It is influenced by various factors, both situational (external and within (internal

  18. Mas d’Is (Penàguila, Alicante: farms and Early Neolithic causewayed camps in the Serpis valley

    Directory of Open Access Journals (Sweden)

    Bernabeu Auban, Joan

    2003-12-01

    Full Text Available In this paper, results from recent archaeological field work carried out in the Neolithic village of Mas d’Is (Penàguila, Alicante are presented. We focus on an important set of domestic and monumental architectural structures. Integration of data from the site in a regional context allows us to rethink the social relations of the first farmers in the area. At the same time, radiocarbon data from our excavations show a finer chronology of the neolithization in Western Mediterranean, and what is more important to approach its historical process.

    En este trabajo presentamos los resultados de los recientes trabajos llevados a cabo en la aldea neolítica de Mas d’Is (Penàguila, Alicante, centrándonos en las estructuras documentadas. La integración de los datos obtenidos en un contexto regional nos permiten plantear algunas reflexiones sobre la Arqueología social de los primeros agricultores, al tiempo que las dataciones radiocarbónicas permiten ir ajustando la cronología de la neolitización del Mediterráneo Occidental, así como el desarrollo de dicho proceso histórico.

  19. PERANAN GAYA KEPEMIMPINAN YANG EFEKTIF DALAM UPAYA MENINGKATKAN SEMANGAT DAN KEGAIRAHAN KERJA KARYAWAN DI TOSERBA SINAR MAS SIDOARJO

    Directory of Open Access Journals (Sweden)

    Eddy Madiono Sutanto

    2000-01-01

    Full Text Available Leadership represents something that should be possessed by each leader of an organization. The effectiveness of a leader is determined by his ability to influence and direct the members of the organization. In order test the style of leadership which is effective at Toserba Sinar Mas in Sidoarjo, this research seeks to determine the relationship of leadership style with enthusiasm and excitement for work. In this study, it is found that the most effective leadership style is leadership which is adapted to the situation of the people being led. There is an indication that enthusiasm and excitement (measured by the level of absenteeism and worker turnover for work may decline as a result of unfavorable leadership. Abstract in Bahasa Indonesia : Kepemimpinan merupakan suatu hal yang seharusnya dimiliki oleh setiap pemimpin organisasi. Efektivitas seorang pemimpin ditentukan oleh kepiawaiannya mempengaruhi dan mengarahkan para anggotanya. Di dalam rangka untuk menguji gaya kepemimpinan yang efektif di Toserba Sinar Mas, Sidoarjo, maka penelitian ini dilakukan untuk membuktikan hubungan antara gaya kepemimpinan dengan semangat dan kegairahan kerja. Di dalam penelitian ini diungkapkan bahwa gaya kepemimpinan yang efektif adalah kepemimpinan yang disesuaikan dengan situasi dan kondisi dari orang-orang yang dipimpin. Indikasi turunnya semangat dan kegairahan kerja ditunjukkan dengan tingginya tingkat absensi dan perpindahan karyawan. Hal itu timbul sebagai akibat dari kepemimpinan yang tidak disenangi. Kata kunci: gaya kepemimpinan, semangat kerja, kegairahan kerja, tingkat absensi, tingkat perpindahan

  20. Des schémas équivalents pour les circuits couplés multi-enroulements

    Science.gov (United States)

    Keradec, J. P.; Cogitore, B.; Laveuve, E.; Bensoam, M.

    1994-04-01

    The aim of this paper is to represent the electrical behaviour of any number of magnetically coupled windings with couplers and inductors. Two methods, mathematicaly justified, are proposed. The second one introduces only positive inductances. As an exemple, it is applied to the representation of a three column three phase transformer. The obtained circuits supply the requisite guide to design more complete circuits which allow the high frequency behaviour of wound components to be taken into account, especialy in electronics simulation softwares. Le but de cet article est de traduire le comportement électrique d'un nombre quelconque d'enroulements magnétiquement couplés, par des coupleurs et des inductances. Deux méthodes, établies mathématiquement, sont proposées. La seconde n'introduit que des inductances positives. A titre d'exemple, elle est appliquée à la représentation d'un transformateur triphasé à trois colonnes. Les schémas obtenus fournissent l'indispensable ossature de schémas plus complets, aptes à représenter le comportement haute fréquence des composants bobinés, notamment dans un logiciel de simulation électronique.

  1. Atmospheric retrieval analysis of the directly imaged exoplanet HR 8799b

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jae-Min [University of Zürich, Institute for Theoretical Physics, Winterthurerstrasse 190, CH-8057 Zürich (Switzerland); Heng, Kevin [University of Bern, Center for Space and Habitability, Sidlerstrasse 5, CH-3012 Bern (Switzerland); Irwin, Patrick G. J., E-mail: lee@physik.uzh.ch, E-mail: kevin.heng@csh.unibe.ch, E-mail: irwin@atm.ox.ac.uk [University of Oxford, Atmospheric, Oceanic and Planetary Physics, Clarendon Laboratory, Parks Road, Oxford OX1 3PU (United Kingdom)

    2013-12-01

    Directly imaged exoplanets are unexplored laboratories for the application of the spectral and temperature retrieval method, where the chemistry and composition of their atmospheres are inferred from inverse modeling of the available data. As a pilot study, we focus on the extrasolar gas giant HR 8799b, for which more than 50 data points are available. We upgrade our non-linear optimal estimation retrieval method to include a phenomenological model of clouds that requires the cloud optical depth and monodisperse particle size to be specified. Previous studies have focused on forward models with assumed values of the exoplanetary properties; there is no consensus on the best-fit values of the radius, mass, surface gravity, and effective temperature of HR 8799b. We show that cloud-free models produce reasonable fits to the data if the atmosphere is of super-solar metallicity and non-solar elemental abundances. Intermediate cloudy models with moderate values of the cloud optical depth and micron-sized particles provide an equally reasonable fit to the data and require a lower mean molecular weight. We report our best-fit values for the radius, mass, surface gravity, and effective temperature of HR 8799b. The mean molecular weight is about 3.8, while the carbon-to-oxygen ratio is about unity due to the prevalence of carbon monoxide. Our study emphasizes the need for robust claims about the nature of an exoplanetary atmosphere to be based on analyses involving both photometry and spectroscopy and inferred from beyond a few photometric data points, such as are typically reported for hot Jupiters.

  2. Limited field investigation report for the 100-HR-2 Operable Unit

    International Nuclear Information System (INIS)

    1995-07-01

    This report summarizes the data collection and analysis activities conducted during the 100-HR-2 Operable Unit investigative phase and the associated qualitative risk assessment. The 100-HR-2 Operable Unit contains solid waste burial grounds, an ash pit, burn pits, electrical facilities, septic systems, and support facilities. All known and suspected areas of contamination were classified as solid waste burial grounds or low-priority waste sites based on the collective knowledge of the operable unit managers (representatives from the US Department of Energy, the US Environmental Protection Agency, and Washington State Department of Ecology during the preparation of the 100-HR-2 Operable Unit Work Plan (DOE-RL 1993f). Solid waste burial grounds were judged to pose sufficient risk(s), through one or more pathways, to require evaluation for an interim remedial measure as per the Hanford Past-Practice Strategy (DOE-RL 1991) and negotiations with the Department of Energy, US Environmental Protection Agency, and Washington State Department of Ecology. An interim remedial measure is intended to achieve remedies that are likely to lead to a final record of decision. Low-priority sites are those judged not to pose significant risk to require the streamlined evaluation. There were six low-priority waste sites and seven solid waste burial grounds identified. The purpose of this report is to: (1) provide a summary of site investigative activities; (2) refine the conceptual exposure model (as needed); (3) identify chemical- and location-specific corrective action requirements; and 4) provide a human health and ecological QRA associated with solid waste burial grounds

  3. Organizations' Ways of Employing Early Retirees: The Role of Age-Based HR Policies.

    Science.gov (United States)

    Oude Mulders, Jaap; Henkens, Kène; Schippers, Joop

    2015-06-01

    We examine whether from an organizational perspective it is possible to distinguish different ways of employing early retirees and explore how the employment of early retirees is related to the application of 4 age-based human resource (HR) policies, namely demotion, offering training opportunities to older workers, offering early retirement, and allowing flexible working hours. We perform a latent class analysis on a sample of 998 Dutch organizations in order to categorize them based on 3 dimensions of their employment of early retirees. We then run a multinomial logistic regression to relate the employment of early retirees to the 4 age-based HR policies. We distinguish 4 types of organizations based on their way of employing early retirees: nonusers (52.6%), users for mainly standard work (20.8%), users for mainly nonstandard work (9.8%), and users for standard and nonstandard work (16.7%). We find that organizations that apply demotion, offer early retirement, and allow flexible working hours are more likely to be users for mainly standard work. Also, organizations that do not offer early retirement are less likely to employ early retirees. Age-based HR policies, especially demotion, offering early retirement, and allowing flexible working hours, are conducive to the employment of early retirees for mainly standard work. Broader implementation of these policies may provide opportunities for older workers to make a more gradual transition from work to retirement. © The Author 2013. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  4. Work – Life Balance Practices in Romanian Organisations – A Pilot Study Conducted on HR Professionals

    Directory of Open Access Journals (Sweden)

    Ramona IGREȚ

    2016-06-01

    Full Text Available Work – life balance is becoming a very debated subject in the Romanian business context, especially in multinationals and large Romanian companies. This paper’s main objective is to conduct a pilot study regarding work – life balance practices on human resource professionals from Romania. The study’s main purpose is to validate a research questionnaire in order to conduct a more significant research in the future. The questionnaire was applied on 52 HR specialists from different organisations and is structured on five sections: working hours, WLB practices, holiday and time off, flexible working and information about the employer and the job.

  5. Bone Structural Changes and Estimated Strength After Gastric Bypass Surgery Evaluated by HR-pQCT

    DEFF Research Database (Denmark)

    Frederiksen, Katrine Diemer; Hanson, Stine; Hansen, Stinus

    2016-01-01

    Roux-en-Y gastric bypass surgery (RYGB) is an effective treatment of morbid obesity, with positive effects on obesity-related complications. The treatment is associated with bone loss, which in turn might increase fracture risk. The aim of this study was to evaluate changes in bone mineral density...... (BMD) and bone architecture assessed using dual-energy X-ray absorptiometry (DXA) and high-resolution peripheral quantitative computed tomography (HR-pQCT), 6 and 12 months after RYGB, and correlate them to changes in selected biochemical markers. A prospective cohort study included 25 morbidly obese...

  6. Incorporation of phosphorus guest ions in the calcium silicate phases of Portland cement from 31P MAS NMR spectroscopy.

    Science.gov (United States)

    Poulsen, Søren L; Jakobsen, Hans J; Skibsted, Jørgen

    2010-06-21

    Portland cements may contain small quantities of phosphorus (typically below 0.5 wt % P(2)O(5)), originating from either the raw materials or alternative sources of fuel used to heat the cement kilns. This work reports the first (31)P MAS NMR study of anhydrous and hydrated Portland cements that focuses on the phase and site preferences of the (PO(4))(3-) guest ions in the main clinker phases and hydration products. The observed (31)P chemical shifts (10 to -2 ppm), the (31)P chemical shift anisotropy, and the resemblance of the lineshapes in the (31)P and (29)Si MAS NMR spectra strongly suggest that (PO(4))(3-) units are incorporated in the calcium silicate phases, alite (Ca(3)SiO(5)) and belite (Ca(2)SiO(4)), by substitution for (SiO(4))(4-) tetrahedra. This assignment is further supported by a determination of the spin-lattice relaxation times for (31)P in alite and belite, which exhibit the same ratio as observed for the corresponding (29)Si relaxation times. From simulations of the intensities, observed in inversion-recovery spectra for a white Portland cement, it is deduced that 1.3% and 2.1% of the Si sites in alite and belite, respectively, are replaced by phosphorus. Charge balance may potentially be achieved to some extent by a coupled substitution mechanism where Ca(2+) is replaced by Fe(3+) ions, which may account for the interaction of the (31)P spins with paramagnetic Fe(3+) ions as observed for the ordinary Portland cements. A minor fraction of phosphorus may also be present in the separate phase Ca(3)(PO(4))(2), as indicated by the observation of a narrow resonance at delta((31)P) = 3.0 ppm for two of the studied cements. (31)P{(1)H} CP/MAS NMR spectra following the hydration of a white Portland cement show that the resonances from the hydrous phosphate species fall in the same spectral range as observed for (PO(4))(3-) incorporated in alite. This similarity and the absence of a large (31)P chemical shift ansitropy indicate that the hydrous (PO(4

  7. DNA-repair protein hHR23a alters its protein structure upon binding proteasomal subunit S5a

    Science.gov (United States)

    Walters, Kylie J.; Lech, Patrycja J.; Goh, Amanda M.; Wang, Qinghua; Howley, Peter M.

    2003-01-01

    The Rad23 family of proteins, including the human homologs hHR23a and hHR23b, stimulates nucleotide excision repair and has been shown to provide a novel link between proteasome-mediated protein degradation and DNA repair. In this work, we illustrate how the proteasomal subunit S5a regulates hHR23a protein structure. By using NMR spectroscopy, we have elucidated the structure and dynamic properties of the 40-kDa hHR23a protein and show it to contain four structured domains connected by flexible linker regions. In addition, we reveal that these domains interact in an intramolecular fashion, and by using residual dipolar coupling data in combination with chemical shift perturbation analysis, we present the hHR23a structure. By itself, hHR23a adopts a closed conformation defined by the interaction of an N-terminal ubiquitin-like domain with two ubiquitin-associated domains. Interestingly, binding of the proteasomal subunit S5a disrupts the hHR23a interdomain interactions and thereby causes it to adopt an opened conformation. PMID:14557549

  8. Role of high resolution contrast-enhanced magnetic resonance angiography (HR CeMRA) in management of arterial complications of the renal transplant

    International Nuclear Information System (INIS)

    Ismaeel, M. Maged; Abdel-Hamid, Azza

    2011-01-01

    Introduction: Transplant renal artery (RA) stenosis (TRAS) is the most frequent posttransplantation vascular complication. Contrast enhanced magnetic resonance (CeMRA) angiography has been established as the preferred imaging technique for the evaluation of TRAS because it does not require the use of iodinated contrast material and does not expose the patient to ionizing radiation. Digital subtraction angiography (DSA) is the gold standard in the evaluation of arterial tree of the renal allograft. Aim of the work: This study was carried out to assess the accuracy of CeMRA in the detection of arterial complications after renal transplantation. Patients and methods: Thirty renal transplant patients with suspected arterial complications in which both CeMRA and DSA were performed were included in the study. The HR CeMRA shows 93.7% sensitivity, 80% specificity, 88.2% positive predictive value, 88.9% negative predictive value and 88.5% accuracy. Conclusion: HR CeMRA is an accurate reliable tool in the assessment of arterial complications after renal transplantation. It may replace DSA as a diagnostic modality with reservation of interventional techniques for endovascular treatment of suitable cases.

  9. Role of high resolution contrast-enhanced magnetic resonance angiography (HR CeMRA) in management of arterial complications of the renal transplant

    Energy Technology Data Exchange (ETDEWEB)

    Ismaeel, M. Maged [Suez Canal University (Egypt); Abdel-Hamid, Azza, E-mail: azza4951@hotmail.com [Suez Canal University (Egypt)

    2011-08-15

    Introduction: Transplant renal artery (RA) stenosis (TRAS) is the most frequent posttransplantation vascular complication. Contrast enhanced magnetic resonance (CeMRA) angiography has been established as the preferred imaging technique for the evaluation of TRAS because it does not require the use of iodinated contrast material and does not expose the patient to ionizing radiation. Digital subtraction angiography (DSA) is the gold standard in the evaluation of arterial tree of the renal allograft. Aim of the work: This study was carried out to assess the accuracy of CeMRA in the detection of arterial complications after renal transplantation. Patients and methods: Thirty renal transplant patients with suspected arterial complications in which both CeMRA and DSA were performed were included in the study. The HR CeMRA shows 93.7% sensitivity, 80% specificity, 88.2% positive predictive value, 88.9% negative predictive value and 88.5% accuracy. Conclusion: HR CeMRA is an accurate reliable tool in the assessment of arterial complications after renal transplantation. It may replace DSA as a diagnostic modality with reservation of interventional techniques for endovascular treatment of suitable cases.

  10. SPECTROSCOPIC AND PHOTOMETRIC VARIABILITY IN THE A0 SUPERGIANT HR 1040

    International Nuclear Information System (INIS)

    Corliss, David J.; Morrison, Nancy D.; Adelman, Saul J.

    2015-01-01

    A time-series analysis of spectroscopic and photometric observables of the A0 Ia supergiant HR 1040 has been performed, including equivalent widths, radial velocities, and Strömgren photometric indices. The data, obtained from 1993 through 2007, include 152 spectroscopic observations from the Ritter Observatory 1 m telescope and 269 Strömgren photometric observations from the Four College Automated Photoelectric Telescope. Typical of late B- and early A-type supergiants, HR 1040 has a highly variable Hα profile. The star was found to have an intermittent active phase marked by correlation between the Hα absorption equivalent width and blue-edge radial velocity and by photospheric connections observed in correlations to equivalent width, second moment and radial velocity in Si ii λλ6347, 6371. High-velocity absorption (HVA) events were observed only during this active phase. HVA events in the wind were preceded by photospheric activity, including Si ii radial velocity oscillations 19–42 days prior to onset of an HVA event and correlated increases in Si ii W λ and second moment from 13 to 23 days before the start of the HVA event. While increases in various line equivalent widths in the wind prior to HVA events have been reported in the past in other stars, our finding of precursors in enhanced radial velocity variations in the wind and at the photosphere is a new result

  11. New spectro-photometric characterization of the substellar object HR 2562 B using SPHERE

    Science.gov (United States)

    Mesa, D.; Baudino, J.-L.; Charnay, B.; D'Orazi, V.; Desidera, S.; Boccaletti, A.; Gratton, R.; Bonnefoy, M.; Delorme, P.; Langlois, M.; Vigan, A.; Zurlo, A.; Maire, A.-L.; Janson, M.; Antichi, J.; Baruffolo, A.; Bruno, P.; Cascone, E.; Chauvin, G.; Claudi, R. U.; De Caprio, V.; Fantinel, D.; Farisato, G.; Feldt, M.; Giro, E.; Hagelberg, J.; Incorvaia, S.; Lagadec, E.; Lagrange, A.-M.; Lazzoni, C.; Lessio, L.; Salasnich, B.; Scuderi, S.; Sissa, E.; Turatto, M.

    2018-05-01

    Aims: HR 2562 is an F5V star located at 33 pc from the Sun hosting a substellar companion that was discovered using the Gemini planet imager (GPI) instrument. The main objective of the present paper is to provide an extensive characterization of the substellar companion, by deriving its fundamental properties. Methods: We observed HR 2562 with the near-infrared branch composed by the integral field spectrograph (IFS) and the infrared dual band spectrograph (IRDIS) of the spectro-polarimetric high-contrast exoplanet research (SPHERE) instrument at the very large telescope (VLT). During our observations IFS was operating in the Y J band, while IRDIS was observing with the H broadband filter. The data were reduced with the dedicated SPHERE GTO pipeline, which is custom designed for this instrument. On the reduced images, we then applied the post-processing procedures that are specifically prepared to subtract the speckle noise. Results: The companion is clearly detected in both IRDIS and IFS datasets. We obtained photometry in three different spectral bands. The comparison with template spectra allowed us to derive a spectral type of T2-T3 for the companion. Using both evolutionary and atmospheric models we inferred the main physical parameters of the companion obtaining a mass of 32 ± 14 MJup, Teff = 1100 ± 200 K, and log g = 4.75 ± 0.41. Based on observations made with European Southern Observatory (ESO) telescopes at Paranal Observatory in Chile, under program ID 198.C-0209(D).

  12. Palbociclib: A Review in HR-Positive, HER2-Negative, Advanced or Metastatic Breast Cancer.

    Science.gov (United States)

    Kim, Esther S; Scott, Lesley J

    2017-06-01

    Oral palbociclib (Ibrance®) is a first-in-class, highly selective inhibitor of cyclin-dependent kinases 4 and 6 (i.e. a CDK4/6 inhibitor). It is indicated for the treatment of women with HR-positive, HER2-negative advanced or metastatic breast cancer, in combination with an aromatase inhibitor as initial endocrine-based therapy, and in combination with fulvestrant (with or without a luteinizing hormone-releasing hormone agonist) in those previously treated with endocrine therapy. In clinical trials, palbociclib in combination with letrozole as initial endocrine-based therapy in postmenopausal women (PALOMA-1 and PALOMA-2), or in combination with fulvestrant in pre-, peri-, or postmenopausal women with disease progression after endocrine therapy (PALOMA-3), significantly prolonged progression-free survival (PFS) and improved clinical benefit response (CBR) rates. Neutropenia was the most commonly reported any-grade and grade ≥ 3 adverse event. It was infrequently associated with febrile neutropenia (<2%) and generally manageable with a palbociclib dose delay, interruption or reduction, without the routine use of growth factors, and without affecting efficacy. In conclusion, oral palbociclib combination therapy is a valuable emerging option for use in patients with HR-positive, HER2-negative advanced or metastatic breast cancer.

  13. Evaluation of bone microstructure in CRPS-affected upper limbs by HR-pQCT.

    Science.gov (United States)

    Mussawy, Haider; Schmidt, Tobias; Rolvien, Tim; Rüther, Wolfgang; Amling, Michael

    2017-01-01

    Complex regional pain syndrome (CRPS) is a major complication after trauma, surgery, and/or immobilization of an extremity. The disease often starts with clinical signs of local inflammation and develops into a prolonged phase that is characterized by trophic changes and local osteoporosis and sometimes results in functional impairment of the affected limb. While the pathophysiology of CRPS remains poorly understood, increased local bone resorption plays an undisputed pivotal role. The aim of this retrospective clinical study was to assess the bone microstructure in patients with CRPS. Patients with CRPS type I of the upper limb whose affected and unaffected distal radii were analyzed by high-resolution peripheral quantitative computed tomography (HR-pQCT) were identified retrospectively. The osteology laboratory data and dual-energy X-ray absorptiometry (DXA) images of the left femoral neck and lumbar spine, which were obtained on the same day as HR-pQCT, were extracted from the medical records. Five patients were identified. The CRPS-affected upper limbs had significantly lower trabecular numbers and higher trabecular thicknesses than the unaffected upper limbs. However, the trabecular bone volume to total bone volume and cortical thickness values of the affected and unaffected sides were similar. Trabecular thickness tended to increase with time since disease diagnosis. CRPS associated with significant alterations in the bone microstructure of the affected upper limb that may amplify as the duration of disease increases.

  14. A count rate model for PET and its application to an LSO HR PLUS scanner

    International Nuclear Information System (INIS)

    Moisan, C.; Rogers, J.G.; Douglas, J.L.

    1996-10-01

    We present a count rate model for PET. Considering a standard 20 x 20 cm phantom in the field-of-view of a cylindrical septaless tomograph, the model computes the acceptance to prompt and random events from simple geometric considerations. Dead time factors at all stages of a typical event acquisition architecture are calculated from specified processing clock cycles. Validations of the model's predictions against the measured performances of the ECAT-953B and the EXACT HR PLUS are presented. The model is then used to investigate the benefit of using detectors made of LSO in the EXACT HR PLUS scanner geometry. The results indicate that in replacing BGO by the faster LSO, one can count on an increase of the peak noise-equivalent-count rate by a factor 2.2. This gain will be achieved by using a 5 nsec coincidence window, buckets operating on 128 nsec clock cycle, and front-end data acquisition that can sustain a total rate of 2.9 MHz. (authors)

  15. Sex- and Site-Specific Normative Data Curves for HR-pQCT.

    Science.gov (United States)

    Burt, Lauren A; Liang, Zhiying; Sajobi, Tolulope T; Hanley, David A; Boyd, Steven K

    2016-11-01

    The purpose of this study was to develop age-, site-, and sex-specific centile curves for common high-resolution peripheral quantitative computed tomography (HR-pQCT) and finite-element (FE) parameters for males and females older than 16 years. Participants (n = 866) from the Calgary cohort of the Canadian Multicentre Osteoporosis Study (CaMos) between the ages of 16 and 98 years were included in this study. Participants' nondominant radius and left tibia were scanned using HR-pQCT. Standard and automated segmentation methods were performed and FE analysis estimated apparent bone strength. Centile curves were generated for males and females at the tibia and radius using the generalized additive models for location, scale, and shape (GAMLSS) package in R. After GAMLSS analysis, age-, sex-, and site-specific centiles (10th, 25th, 50th, 75th, 90th) for total bone mineral density and trabecular number as well as failure load have been calculated. Clinicians and researchers can use these reference curves as a tool to assess bone health and changes in bone quality. © 2016 American Society for Bone and Mineral Research. © 2016 American Society for Bone and Mineral Research.

  16. Focal plane AIT sequence: evolution from HRG-Spot 5 to Pleiades HR

    Science.gov (United States)

    Le Goff, Roland; Pranyies, Pascal; Toubhans, Isabelle

    2017-11-01

    Optical and geometrical image qualities of Focal Planes, for "push-broom" high resolution remote sensing satellites, require the implementation of specific means and methods for the AIT sequence. Indeed the geometric performances of the focal plane mainly axial focusing and transverse registration, are duly obtained on the basis of adjustment, setting and measurement of optical and CCD components with an accuracy of a few microns. Since the end of the 1970s, EADS-SODERN has developed a series of detection units for earth observation instruments like SPOT and Helios. And EADS-SODERN is now responsible for the development of the Pleiades High Resolution Focal Plane assembly. This paper presents the AIT sequences. We introduce all the efforts, innovative solutions and improvements made on the assembly facilities to match the technical evolutions and breakthrough of the Pleiades HR FP concept in comparison with the previous High Resolution Geometric SPOT 5 Focal Plane. The main evolution drivers are the implementation of strip filters and the realization of 400 mm continuous retinas. For Pleiades HR AIT sequence, three specific integration and measuring benches, corresponding with the different assembly stages, are used: a 3-D non-contact measurement machine for the assembly of detection module, a 3-D measurement machine for mirror integration on the main Focal Plane SiC structure, and a 3-D geometric coordinates control bench to focus detection module lines and to ensure they are well registered together.

  17. Factors of Nonlinear-ultrasonic Detection and Its Application to HR3C Fireside Corrosion

    Directory of Open Access Journals (Sweden)

    QIN Peng

    2016-11-01

    Full Text Available Based on the discussion of the factors influencing the nonlinear ultrasonic testing, the feasibility of nondestructive evaluation of HR3C fireside corrosion was investigated using nonlinear ultrasonic testing. The results show that the number of pulse string is no more than 2df/c and the installation of Hanning window is helpful to reduce the disturbance of the system, in addition, the rough surface of the sample has a significant impact on the nonlinear parameter β. The nonlinear coefficient demonstrates a phased growth trend as corrosion time prolongs. At the initial stage of corrosion(within 50h,there are small increments within 20% in the nonlinear coefficient, however,the nonlinear coefficient β is increased obviously with the duration time to 150h. Compared with un-corroded sample, the amplification in the sample corroded for 200h reaches to 260%. The monotonous varieties in nonlinear coefficient are consistent with the aggravation of corrosion damage,hence,it is feasible to nondestructively evaluate HR3C fireside corrosion by means of ultrasonic nonlinear testing.

  18. Operating characteristics of a 0.87 kW-hr flywheel energy storage module

    Science.gov (United States)

    Loewenthal, S. H.; Scibbe, H. W.; Parker, R. D.; Zaretsky, E. V.

    1985-01-01

    Discussion is given of the design and loss characteristics of 0.87 kW-hr (peak) flywheel energy storage module suitable for aerospace and automotive applications. The maraging steel flywheel rotor, a 46-cm- (18-in-) diameter, 58-kg (128-lb) tapered disk, delivers 0.65 kW-hr of usable energy between operating speeds of 10,000 and 20,000 rpm. The rotor is supported by 20- and 25-mm bore diameter, deep-groove ball bearings, lubricated by a self-replenishing wick type lubrication system. To reduce aerodynamic losses, the rotor housing was evacuated to vacuum levels from 40 to 200 millitorr. Dynamic rotor instabilities uncovered during testing necessitated the use of an elastometric-bearing damper to limit shaft excursions. Spindown losses from bearing, seal, and aerodynamic drag at 50 millitorr typically ranged from 64 to 193 W at 10,000 and 20,000 rpm, respectively. Discharge efficiency of the flywheel system exceeded 96 percent at torque levels greater than 21 percent of rated torque.

  19. A critical role of the nuclear receptor HR3 in regulation of gonadotrophic cycles of the mosquito Aedes aegypti.

    Directory of Open Access Journals (Sweden)

    Daniel Mane-Padros

    Full Text Available The orphan nuclear receptor HR3 is essential for developmental switches during insect development and metamorphosis regulated by 20-hydroxyecdysone (20E. Reproduction of female mosquitoes of the major vector of Dengue fever, Aedes aegypti, is cyclic because of its dependence on blood feeding. 20E is an important hormone regulating vitellogenic events in this mosquito; however, any role for HR3 in 20E-driven reproductive events has not been known. Using RNA interference (RNAi approach, we demonstrated that Aedes HR3 plays a critical role in a timely termination of expression of the vitellogenin (Vg gene encoding the major yolk protein precursor. It is also important for downregulation of the Target-of-Rapamycin pathway and activation of programmed autophagy in the Aedes fat body at the end of vitellogenesis. HR3 is critical in activating betaFTZ-F1, EcRB and USPA, the expressions of which are highly elevated at the end of vitellogenesis. RNAi depletion of HR3 (iHR3 prior to the first gonadotrophic cycle affects a normal progression of the second gonadotrophic cycle. Most of ovaries 24 h post second blood meal from iHR3 females in the second cycle were small with follicles that were only slightly different in length from of those of resting stage. In addition, these iHR3 females laid a significantly reduced number of eggs per mosquito as compared to those of iMal and the wild type. Our results indicate an important role of HR3 in regulation of 20E-regulated developmental switches during reproductive cycles of A. aegypti females.

  20. Deep thermal infrared imaging of HR 8799 bcde: new atmospheric constraints and limits on a fifth planet

    Energy Technology Data Exchange (ETDEWEB)

    Currie, Thayne; Cloutier, Ryan; Jayawardhana, Ray [Department of Astronomy and Astrophysics, University of Toronto, 50 St. George Street, Toronto, ON M5S 3H4 (Canada); Burrows, Adam [Department of Astrophysical Science, Princeton University, 4 Ivy Lane, Princeton, NJ 08544 (United States); Girard, Julien H. [European Southern Observatory, Alonso de Córdova 3107, Vitacura, Casilla 19001, Santiago (Chile); Fukagawa, Misato [Graduate School of Science, Osaka University, 1-1 Machikaneyama, Toyonaka, Osaka 560-0043 (Japan); Sorahana, Satoko [Department of Astronomy, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033 (Japan); Kuchner, Marc [Exoplanets and Stellar Astrophysics Laboratory, NASA Goddard Space Flight Center, Code 667, Greenbelt, MD 20771 (United States); Kenyon, Scott J. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Madhusudhan, Nikku [Institute of Astronomy, University of Cambridge, Madingley Road, Cambridge CB3 0HA (United Kingdom); Itoh, Yoichi [Nishi-Harima Astronomical Observatory, Center for Astronomy, University of Hyago, 407-2 Nishigaichi, Sayo, Hyogo 679-5313 (Japan); Matsumura, Soko [School of Engineering, Physics, and Mathematics, University of Dundee, Dundee DD1 4HN (United Kingdom); Pyo, Tae-Soo [National Astronomical Observatory of Japan, 650 N. Aohoku Place, Hilo, HI 96720 (United States)

    2014-11-10

    We present new L' (3.8 μm) and Brα (4.05 μm) data and reprocessed archival L' data for the young, planet-hosting star HR 8799 obtained with Keck/NIRC2, VLT/NaCo, and Subaru/IRCS. We detect all four HR 8799 planets in each data set at a moderate to high signal-to-noise ratio (S/N ≳ 6-15). We fail to identify a fifth planet, 'HR 8799 f', at r < 15 AU at a 5σ confidence level: one suggestive, marginally significant residual at 0.''2 is most likely a point-spread function artifact. Assuming companion ages of 30 Myr and the Baraffe planet cooling models, we rule out an HR 8799 f with a mass of 5 M{sub J} (7 M{sub J} ), 7 M{sub J} (10 M{sub J} ), or 12 M{sub J} (13 M{sub J} ) at r {sub proj} ∼ 12 AU, 9 AU, and 5 AU, respectively. All four HR 8799 planets have red early T dwarf-like L' – [4.05] colors, suggesting that their spectral energy distributions peak in between the L' and M' broadband filters. We find no statistically significant difference in HR 8799 cde's color. Atmosphere models assuming thick, patchy clouds appear to better match HR 8799 bcde's photometry than models assuming a uniform cloud layer. While non-equilibrium carbon chemistry is required to explain HR 8799 b and c's photometry/spectra, evidence for it from HR 8799 d and e's photometry is weaker. Future, deep-IR spectroscopy/spectrophotometry with the Gemini Planet Imager, SCExAO/CHARIS, and other facilities may clarify whether the planets are chemically similar or heterogeneous.

  1. Deep thermal infrared imaging of HR 8799 bcde: new atmospheric constraints and limits on a fifth planet

    International Nuclear Information System (INIS)

    Currie, Thayne; Cloutier, Ryan; Jayawardhana, Ray; Burrows, Adam; Girard, Julien H.; Fukagawa, Misato; Sorahana, Satoko; Kuchner, Marc; Kenyon, Scott J.; Madhusudhan, Nikku; Itoh, Yoichi; Matsumura, Soko; Pyo, Tae-Soo

    2014-01-01

    We present new L' (3.8 μm) and Brα (4.05 μm) data and reprocessed archival L' data for the young, planet-hosting star HR 8799 obtained with Keck/NIRC2, VLT/NaCo, and Subaru/IRCS. We detect all four HR 8799 planets in each data set at a moderate to high signal-to-noise ratio (S/N ≳ 6-15). We fail to identify a fifth planet, 'HR 8799 f', at r < 15 AU at a 5σ confidence level: one suggestive, marginally significant residual at 0.''2 is most likely a point-spread function artifact. Assuming companion ages of 30 Myr and the Baraffe planet cooling models, we rule out an HR 8799 f with a mass of 5 M J (7 M J ), 7 M J (10 M J ), or 12 M J (13 M J ) at r proj ∼ 12 AU, 9 AU, and 5 AU, respectively. All four HR 8799 planets have red early T dwarf-like L' – [4.05] colors, suggesting that their spectral energy distributions peak in between the L' and M' broadband filters. We find no statistically significant difference in HR 8799 cde's color. Atmosphere models assuming thick, patchy clouds appear to better match HR 8799 bcde's photometry than models assuming a uniform cloud layer. While non-equilibrium carbon chemistry is required to explain HR 8799 b and c's photometry/spectra, evidence for it from HR 8799 d and e's photometry is weaker. Future, deep-IR spectroscopy/spectrophotometry with the Gemini Planet Imager, SCExAO/CHARIS, and other facilities may clarify whether the planets are chemically similar or heterogeneous.

  2. Determination of structure of oriented samples using two-dimensional solid state NMR techniques

    International Nuclear Information System (INIS)

    Jin Hong; Harbison, G.S.

    1990-01-01

    One dimensional and two-dimensional MAS techniques can give detailed information about the structure and dynamics of oriented systems. We describe the application of such techniques to the liquid-crystalline polymer poly(p-phenyleneterphtalimide) (PPTA), and thence deduce the solid-state structure of the material. (author). 9 refs.; 6 figs

  3. Residual dipolar couplings in sup 3 sup 1 P MAS spectra of PPh sub 3 substituted cobalt complexes

    CERN Document Server

    Szalontai, G

    2002-01-01

    Residual dipolar couplings between sup 3 sup 1 P- sup 5 sup 9 Co spin pairs were studied in sup 3 sup 1 P MAS spectra of mono- and dinuclear cobalt-triphenylphosphine complexes. These spectra can provide important information such as the scalar coupling between the dipolar phosphorus and the quadrupolar cobalt nuclei normally not available from solution phase studies. In case of complementary (NQR or x-ray) data even the relative orientation of the interacting shielding, dipolar, scalar couplings, and electric field gradient tensors or internuclear distances can be determined. Examples are shown both for well resolved and practically unresolved cases, factors which possibly control the spectral resolution are discussed in detail. (author)

  4. Spin-echo based diagonal peak suppression in solid-state MAS NMR homonuclear chemical shift correlation spectra

    Science.gov (United States)

    Wang, Kaiyu; Zhang, Zhiyong; Ding, Xiaoyan; Tian, Fang; Huang, Yuqing; Chen, Zhong; Fu, Riqiang

    2018-02-01

    The feasibility of using the spin-echo based diagonal peak suppression method in solid-state MAS NMR homonuclear chemical shift correlation experiments is demonstrated. A complete phase cycling is designed in such a way that in the indirect dimension only the spin diffused signals are evolved, while all signals not involved in polarization transfer are refocused for cancellation. A data processing procedure is further introduced to reconstruct this acquired spectrum into a conventional two-dimensional homonuclear chemical shift correlation spectrum. A uniformly 13C, 15N labeled Fmoc-valine sample and the transmembrane domain of a human protein, LR11 (sorLA), in native Escherichia coli membranes have been used to illustrate the capability of the proposed method in comparison with standard 13C-13C chemical shift correlation experiments.

  5. Hydration properties and phosphorous speciation in native, gelatinized and enzymatically modified potato starch analyzed by solid-state MAS NMR

    DEFF Research Database (Denmark)

    Larsen, Flemming H.; Kasprzak, Miroslaw Marek; Lærke, Helle Nygaard

    2013-01-01

    Hydration of granular, gelatinized and molecularly modified states of potato starch in terms of molecular mobility were analyzed by 13C and 31P solid-state MAS NMR. Gelatinization (GEL) tremendously reduced the immobile fraction compared to native (NA) starch granules. This effect was enhanced...... by enzyme-assisted catalytic branching with branching enzyme (BE) or combined BE and β-amylase (BB) catalyzed exo-hydrolysis. Carbons of the glycosidic α-1,6 linkages required high hydration rates before adopting uniform chemical shifts indicating solid-state disorder and poor water accessibility...... regions was only observed in NA starch. Moreover phosphorous was observed in a minor pH-insensitive form and as major phosphate in hydrated GEL and BE starches....

  6. Studies using 27Al MAS NMR of AFm and AFt phases and the formation of Friedel's salt

    International Nuclear Information System (INIS)

    Jones, M.R.; Macphee, D.E.; Chudek, J.A.; Hunter, G.; Lannegrand, R.; Talero, R.; Scrimgeour, S.N.

    2003-01-01

    This paper describes the application of the magic angle spinning (MAS) NMR spectroscopy to study the chemical environment of 27 Al-bearing phases in Portland cement-based concrete. A specific methodology is described that allows reliable spectra to be determined for combinations of different types of cements and fillers (in this case, Portland cement, fly ash, slag, silica fume, metakaolin and limestone filler). As well as the study of 'molecular structure' of cement matrix, the paper reviews the mechanism of Friedel's salt formation in cement systems. Mechanisms based on ion exchange of chloride for hydroxide in hydroxy-AF m and on chloride absorption on formation are discussed. Finally, the nature of the chloride/hydrate binding phenomena are described to provide a reasonable robust and fundamental picture of the role different cements can play in the provision of overall concrete durability to chloride ingress from a chemical perspective

  7. Morphological and Biochemical Characteristics of Fruits of Different Cornelian Cherry (Cornus mas L. Genotypes from Spontaneous Flora

    Directory of Open Access Journals (Sweden)

    Felicia-Constantina CORNESCU

    2017-12-01

    Full Text Available The current study was carried out on six local cornelian cherry (Cornus mas L. genotypes, grown in Turceni town (Gorj county and Baita village (Hunedoara county, in Romania. Several morphological and biochemical characteristics of cultivars were determined. Fruit weight and fruit flesh ratio of the analyzed genotypes ranged from 1.33 to 2.31 g and 61.53 to 78.58% respectively. Soluble solid contents were determined, the lowest noted as 10% and the highest as 25.5%. Results have shown that there was a high diversity in cornelian cherry populations within different ecological areas. Differences were exhibited in terms of fruit size and biochemical characteristics. The results of the study are useful for attempting to select superior genotypes of cornelian cherry for culture.

  8. 27Al MAS NMR spectroscopic identification of reaction intermediates in the carbothermal reduction and nitridation of alumina

    International Nuclear Information System (INIS)

    Jung, Woo-Sik; Chae, Seen-Ae

    2010-01-01

    The reaction intermediates in the carbothermal reduction and nitridation (CRN) reaction of γ-Al 2 O 3 were identified by 27 Al magic-angle spinning (MAS) nuclear magnetic resonance (NMR) spectroscopy. This identification ruled out the possibility of a reaction mechanism involving the gaseous reaction intermediates. In the CRN reaction of γ-Al 2 O 3 , AlO 4 units were converted to AlN stepwise via AlN x O 4-x (x = 1, 2, 3) intermediates, while AlO 6 units were more slowly converted to AlN than AlO 4 units and the NMR peaks of partially nitridated AlO 6 units were not detected. The NMR peak intensities of partially nitridated AlO 4 units became weaker with increasing reaction temperature.

  9. The selection and adaptation of staff as the basis of the successful implementation of HR strategy

    Directory of Open Access Journals (Sweden)

    Vanicheva A.G.

    2016-11-01

    Full Text Available the article deals with questions of effective strategies of HR policy in the field of selection and adaptation of staff in the company. The text gives an information about effective methods of selection and adaptation, also it draws our attention to development of communication between employees. This paper can help to pay managers’ attention to effective selection and adaptation taking into consideration that introduction of a new employee to a position is responsible enough. Probably, first days in a new company are crucial for the system of motivation of HR policy in the development of HR strategy. Much attention is given to stages of adaptation for employee or chief executive.

  10. Deep Thermal Infrared Imaging of HR 8799 bcde: New Atmospheric Constraints and Limits on a Fifth Planet

    OpenAIRE

    Currie, Thayne; Burrows, Adam; Girard, Julien H.; Cloutier, Ryan; Fukagawa, Misato; Sorahana, Satoko; Kuchner, Marc; Kenyon, Scott J.; Madhusudhan, Nikku; Itoh, Yoichi; Jayawardhana, Ray; Matsumura, Soko; Pyo, Tae-Soo

    2014-01-01

    We present new $L^\\prime$ (3.8 $\\mu m$) and Br-$\\alpha$ (4.05 $\\mu m$) data and reprocessed archival $L^\\prime$ data for the young, planet-hosting star HR 8799 obtained with Keck/NIRC2, VLT/NaCo and Subaru/IRCS. We detect all four HR 8799 planets in each dataset at a moderate to high signal-to-noise (SNR $\\gtrsim$ 6-15). We fail to identify a fifth planet, "HR 8799 f", at $r$ $

  11. Antenatal betamethasone attenuates the angiotensin-(1-7)-Mas receptor-nitric oxide axis in isolated proximal tubule cells.

    Science.gov (United States)

    Su, Yixin; Bi, Jianli; Pulgar, Victor M; Chappell, Mark C; Rose, James C

    2017-06-01

    We previously reported a sex-specific effect of antenatal treatment with betamethasone (Beta) on sodium (Na + ) excretion in adult sheep whereby treated males but not females had an attenuated natriuretic response to angiotensin-(1-7) [Ang-(1-7)]. The present study determined the Na + uptake and nitric oxide (NO) response to low-dose Ang-(1-7) (1 pM) in renal proximal tubule cells (RPTC) from adult male and female sheep antenatally exposed to Beta or vehicle. Data were expressed as percentage of basal uptake or area under the curve for Na + or percentage of control for NO. Male Beta RPTC exhibited greater Na + uptake than male vehicle cells (433 ± 28 vs. 330 ± 26%; P 0.05). Ang-(1-7) significantly inhibited Na + uptake in RPTC from vehicle male (214 ± 11%) and from both vehicle (190 ± 14%) and Beta (209 ± 11%) females but failed to attenuate Na + uptake in Beta male cells. Beta exposure also abolished stimulation of NO by Ang-(1-7) in male but not female RPTC. Both the Na + and NO responses to Ang-(1-7) were blocked by Mas receptor antagonist d-Ala 7 -Ang-(1-7). We conclude that the tubular Ang-(1-7)-Mas-NO pathway is attenuated in males and not females by antenatal Beta exposure. Moreover, since primary cultures of RPTC retain both the sex and Beta-induced phenotype of the adult kidney in vivo they appear to be an appropriate cell model to examine the effects of fetal programming on Na + handling by the renal tubules. Copyright © 2017 the American Physiological Society.

  12. Fetal betamethasone exposure attenuates angiotensin-(1-7)-Mas receptor expression in the dorsal medulla of adult sheep.

    Science.gov (United States)

    Marshall, Allyson C; Shaltout, Hossam A; Nautiyal, Manisha; Rose, James C; Chappell, Mark C; Diz, Debra I

    2013-06-01

    Glucocorticoids including betamethasone (BM) are routinely administered to women entering into early preterm labor to facilitate fetal lung development and decrease infant mortality; however, fetal steroid exposure may lead to deleterious long term consequences. In a sheep model of fetal programming, BM-exposed (BMX) offspring exhibit elevated mean arterial pressure (MAP) and decreased baroreflex sensitivity (BRS) for control of heart rate by 0.5-years of age associated with changes in the circulating and renal renin-angiotensin systems (RAS). In the brain solitary tract nucleus, angiotensin (Ang) II actions through the AT1 receptor oppose the beneficial actions of Ang-(1-7) at the Mas receptor for BRS regulation. Therefore, we examined Ang peptides, angiotensinogen (Aogen), and receptor expression in this brain region of exposed and control offspring of 0.5- and 1.8-years of age. Mas protein expression was significantly lower (>40%) in the dorsal medulla of BMX animals at both ages; however, AT1 receptor expression was not changed. BMX offspring exhibited a higher ratio of Ang II to Ang-(1-7) (2.30±0.36 versus 0.99±0.28; p<0.01) and Ang II to Ang I at 0.5-years. Although total Aogen was unchanged, Ang I-intact Aogen was lower in 0.5-year BMX animals (0.78±0.06 vs. 1.94±0.41; p<0.05) suggesting a greater degree of enzymatic processing of the precursor protein in exposed animals. We conclude that in utero BM exposure promotes an imbalance in the central RAS pathways of Ang II and Ang-(1-7) that may contribute to the elevated MAP and lower BRS in this model. Copyright © 2013 Elsevier Inc. All rights reserved.

  13. Valsartan attenuates intimal hyperplasia in balloon-injured rat aortic arteries through modulating the angiotensin-converting enzyme 2-angiotensin-(1-7)-Mas receptor axis.

    Science.gov (United States)

    Li, Yonghong; Cai, Shanglang; Wang, Qixin; Zhou, Jingwei; Hou, Bo; Yu, Haichu; Ge, Zhiming; Guan, Renyan; Liu, Xu

    2016-05-15

    The role of the Mas receptor in the activity of valsartan against intimal hyperplasia is unclear. Herein, we investigated the role of the angiotensin-converting enzyme 2 (ACE2)-angiotensin-(1-7)-Mas receptor axis on the activity of valsartan against intimal hyperplasiain balloon-injured rat aortic arteries. Wistar rats were randomized equally into the sham control group, injured group, and injured plus valsartan (20 mg/kg/d)-treated group. Valsartan significantly attenuated the vascular smooth muscle cell proliferation and intimal and medial thickening on days 14 and 28 after injury. The angiotensin-(1-7) levels as well as ACE2 and Mas receptor mRNA/protein expression were significantly decreased in the injured rats, compared to the uninjured rats; meanwhile, the angiotensin II level as well as the ACE and AT1 receptor mRNA/protein expression were increased (all P valsartan significantly increased the angiotensin-(1-7) levels as well as ACE2 and Mas receptor mRNA/protein expression but decreased the angiotensin II level, ACE and AT1 receptor mRNA/protein expression, as well as the p-ERK protein expression, compared to the injured group (all P valsartan attenuates neointimal hyperplasiain balloon-injured rat aortic arteries through activation of the ACE2-angiotensin-(1-7)-Mas axis as well as inhibition of the ACE-angiotensin II-AT1 and p-ERK pathways. Copyright © 2016 Elsevier Inc. All rights reserved.

  14. Reorientation of the Methyl Group in MAs(III) is the Rate-Limiting Step in the ArsM As(III) S-Adenosylmethionine Methyltransferase Reaction.

    Science.gov (United States)

    Packianathan, Charles; Li, Jiaojiao; Kandavelu, Palani; Sankaran, Banumathi; Rosen, Barry P

    2018-03-01

    The most common biotransformation of trivalent inorganic arsenic (As(III)) is methylation to mono-, di-, and trimethylated species. Methylation is catalyzed by As(III) S -adenosylmethionine (SAM) methyltransferase (termed ArsM in microbes and AS3MT in animals). Methylarsenite (MAs(III)) is both the product of the first methylation step and the substrate of the second methylation step. When the rate of the overall methylation reaction was determined with As(III) as the substrate, the first methylation step was rapid, whereas the second methylation step was slow. In contrast, when MAs(III) was used as the substrate, the rate of methylation was as fast as the first methylation step when As(III) was used as the substrate. These results indicate that there is a slow conformational change between the first and second methylation steps. The structure of CmArsM from the thermophilic alga Cyanidioschyzon merolae sp. 5508 was determined with bound MAs(III) at 2.27 Å resolution. The methyl group is facing the solvent, as would be expected when MAs(III) is bound as the substrate rather than facing the SAM-binding site, as would be expected for MAs(III) as a product. We propose that the rate-limiting step in arsenic methylation is slow reorientation of the methyl group from the SAM-binding site to the solvent, which is linked to the conformation of the side chain of a conserved residue Tyr70.

  15. Sublethal concentrations of 17-AAG suppress homologous recombination DNA repair and enhance sensitivity to carboplatin and olaparib in HR proficient ovarian cancer cells.

    Science.gov (United States)

    Choi, Young Eun; Battelli, Chiara; Watson, Jacqueline; Liu, Joyce; Curtis, Jennifer; Morse, Alexander N; Matulonis, Ursula A; Chowdhury, Dipanjan; Konstantinopoulos, Panagiotis A

    2014-05-15

    The promise of PARP-inhibitors(PARPis) in the management of epithelial ovarian cancer(EOC) is tempered by the fact that approximately 50% of patients with homologous recombination (HR)-proficient tumors do not respond well to these agents. Combination of PARPis with agents that inhibit HR may represent an effective strategy to enhance their activity in HR-proficient tumors. Using a bioinformatics approach, we identified that heat shock protein 90 inhibitors(HSP90i) may suppress HR and thus revert HR-proficient to HR-deficient tumors. Analysis of publicly available gene expression data showed that exposure of HR-proficient breast cancer cell lines to HSP90i 17-AAG(17-allylamino-17-demethoxygeldanamycin) downregulated HR, ATM and Fanconi Anemia pathways. In HR-proficient EOC cells, 17-AAG suppressed HR as assessed using the RAD51 foci formation assay and this was further confirmed using the Direct Repeat-GFP reporter assay. Furthermore, 17-AAG downregulated BRCA1 and/or RAD51 protein levels, and induced significantly more γH2AX activation in combination with olaparib compared to olaparib alone. Finally, sublethal concentrations of 17-AAG sensitized HR-proficient EOC lines to olaparib and carboplatin but did not affect sensitivity of the HR-deficient OVCAR8 line arguing that the 17-AAG mediated sensitization is dependent on suppression of HR. These results provide a preclinical rationale for using a combination of olaparib/17-AAG in HR-proficient EOC.

  16. Ribociclib as First-Line Therapy for HR-Positive, Advanced Breast Cancer.

    Science.gov (United States)

    Hortobagyi, Gabriel N; Stemmer, Salomon M; Burris, Howard A; Yap, Yoon-Sim; Sonke, Gabe S; Paluch-Shimon, Shani; Campone, Mario; Blackwell, Kimberly L; André, Fabrice; Winer, Eric P; Janni, Wolfgang; Verma, Sunil; Conte, Pierfranco; Arteaga, Carlos L; Cameron, David A; Petrakova, Katarina; Hart, Lowell L; Villanueva, Cristian; Chan, Arlene; Jakobsen, Erik; Nusch, Arnd; Burdaeva, Olga; Grischke, Eva-Maria; Alba, Emilio; Wist, Erik; Marschner, Norbert; Favret, Anne M; Yardley, Denise; Bachelot, Thomas; Tseng, Ling-Ming; Blau, Sibel; Xuan, Fengjuan; Souami, Farida; Miller, Michelle; Germa, Caroline; Hirawat, Samit; O'Shaughnessy, Joyce

    2016-11-03

    The inhibition of cyclin-dependent kinases 4 and 6 (CDK4/6) could potentially overcome or delay resistance to endocrine therapy in advanced breast cancer that is positive for hormone receptor (HR) and negative for human epidermal growth factor receptor 2 (HER2). In this randomized, placebo-controlled, phase 3 trial, we evaluated the efficacy and safety of the selective CDK4/6 inhibitor ribociclib combined with letrozole for first-line treatment in 668 postmenopausal women with HR-positive, HER2-negative recurrent or metastatic breast cancer who had not received previous systemic therapy for advanced disease. We randomly assigned the patients to receive either ribociclib (600 mg per day on a 3-weeks-on, 1-week-off schedule) plus letrozole (2.5 mg per day) or placebo plus letrozole. The primary end point was investigator-assessed progression-free survival. Secondary end points included overall survival, overall response rate, and safety. A preplanned interim analysis was performed on January 29, 2016, after 243 patients had disease progression or died. Prespecified criteria for superiority required a hazard ratio of 0.56 or less with P<1.29×10 -5 . The duration of progression-free survival was significantly longer in the ribociclib group than in the placebo group (hazard ratio, 0.56; 95% CI, 0.43 to 0.72; P=3.29×10 -6 for superiority). The median duration of follow-up was 15.3 months. After 18 months, the progression-free survival rate was 63.0% (95% confidence interval [CI], 54.6 to 70.3) in the ribociclib group and 42.2% (95% CI, 34.8 to 49.5) in the placebo group. In patients with measurable disease at baseline, the overall response rate was 52.7% and 37.1%, respectively (P<0.001). Common grade 3 or 4 adverse events that were reported in more than 10% of the patients in either group were neutropenia (59.3% in the ribociclib group vs. 0.9% in the placebo group) and leukopenia (21.0% vs. 0.6%); the rates of discontinuation because of adverse events were 7.5% and 2

  17. Value-based HR practices, i-deals and clinical error control with CSR as a moderator.

    Science.gov (United States)

    Luu, Tuan; Rowley, Chris; Siengthai, Sununta; Thanh Thao, Vo

    2017-05-08

    Purpose Notwithstanding the rising magnitude of system factors in patient safety improvement, "human factors" such as idiosyncratic deals (i-deals) which also contribute to the adjustment of system deficiencies should not be neglected. The purpose of this paper is to investigate the role of value-based HR practices in catalyzing i-deals, which then influence clinical error control. The research further examines the moderating role of corporate social responsibility (CSR) on the effect of value-based HR practices on i-deals. Design/methodology/approach The data were collected from middle-level clinicians from hospitals in the Vietnam context. Findings The research results confirmed the effect chain from value-based HR practices through i-deals to clinical error control with CSR as a moderator. Originality/value The HRM literature is expanded through enlisting i-deals and clinical error control as the outcomes of HR practices.

  18. HR policies and practices in vocational education and training institutions. Understanding the implementation gap through the lens of discourses

    NARCIS (Netherlands)

    Runhaar, P.R.; Runhaar, H.A.C.

    2012-01-01

    Vocational education and training (VET) institutions face serious challenges, like educational innovations and upcoming teacher shortages, which require them to invest in their human capital. However, the implementation of human resources (HR) policies and practices often stagnates. Using the

  19. HR policies and practices in vocational education and training institutions: understanding the implementation gap through the lens of discourses

    NARCIS (Netherlands)

    Runhaar, P.R.; Runhaar, H.

    2012-01-01

    Vocational education and training (VET) institutions face serious challenges, like educational innovations and upcoming teacher shortages, which require them to invest in their human capital. However, the implementation of human resources (HR) policies and practices often stagnates. Using the Dutch

  20. Lielveikalu RIMI reklāmas kampaņas ─ auditorijas uzmanības piesaistes analīze

    OpenAIRE

    Fjodorova, Margarita

    2008-01-01

    Mana darba tēma ir „Lielveikalu „RIMI” reklāmas kampaņas – auditorijas uzmanības piesaistes analīze.” Es apskatu 2003. – 2008.gada „RIMI” video reklāmas, lai pierādītu sava darba hipotēzi, ka „RIMI” lielveikalu video reklāmās laika posmā no 2003. līdz 2008. gadam nav bijis vienotu auditorijas uzmanības piesaistes elementu, bet tie tika ieturēti tikai kādas konkrētas reklāmas kampaņas robežās kā galvenie auditorijas uzmanības piesaistes elementi. Sava darba teorētiskajā daļā es pieturēšos pie ...

  1. CONCEPTUALIZACIÓN Y ANÁLISIS DE UN SISTEMA MULTI-AGENTE PEDAGÓGICO UTILIZANDO LA METODOLOGÍA MAS-COMMONKADS

    Directory of Open Access Journals (Sweden)

    JOVANI ALBERTO JIMÉNEZ BUILES

    2009-01-01

    Full Text Available En este artículo se presentan la conceptualización y el análisis de un sistema multi-agente (MAS pedagógico utilizando la metodología MAS-CommonKADS; la cual es una de las más reconocidaspara el modelado de MAS. El propósito de la fase de conceptualización es comprender el problema, identificar los actores activos y pasivo, además de elaborar los requisitos que permitan formular unos objetivos para generar la solución. En la fase de análisis se definen los modelos de agente, tareas, coordinación, comunicación, organizacióny experiencia (conocimientos. Ambas fases fueron validadas mediante la construcción del ambiente multi agente pedagógico ALLEGRO.

  2. Draft genome sequence of a human-associated isolate of Haloferax alexandrinus strain Arc-hr, an extremely halophilic archaea.

    Science.gov (United States)

    Khelaifia, S; Caputo, A; Djossou, F; Raoult, D

    2017-01-01

    We report the draft genome sequence of Haloferax alexandrinus strain Arc-hr (CSUR P798), isolated from the human gut of a 10-year-old Amazonian individual. Its 3 893 626 bp genome exhibits a 66.00% GC content. The genome of the strain Arc-hr contains 37 genes identified as ORFans, seven genes associated to halocin and 11 genes associated with polyketide synthases or nonribosomal peptide synthetases.

  3. Are They Fit For Purpose? Exploring Managers' Experiences of UK HR Graduates & Employability Implications: A Pilot Study

    OpenAIRE

    Mullen, Emma

    2014-01-01

    The purpose of this research is to expand on existing understandings of graduate employability through exploring the lived experiences and perceptions of key informants, in this case, those with direct line management responsibilities for graduates. The context of this research is focused on Human Resources (HR) graduates, a discipline that has seen little qualitative inquiry across the Higher Education (HE), employability and HR literature, and which is currently dominated by skills-led appr...

  4. A combined multiwavelength VLA/ALMA/Chandra study unveils the complex magnetosphere of the B-type star HR5907

    Science.gov (United States)

    Leto, P.; Trigilio, C.; Oskinova, L. M.; Ignace, R.; Buemi, C. S.; Umana, G.; Ingallinera, A.; Leone, F.; Phillips, N. M.; Agliozzo, C.; Todt, H.; Cerrigone, L.

    2018-05-01

    We present new radio/millimeter measurements of the hot magnetic star HR 5907 obtained with the VLA and ALMA interferometers. We find that HR 5907 is the most radio luminous early type star in the cm-mm band among those presently known. Its multi-wavelength radio light curves are strongly variable with an amplitude that increases with radio frequency. The radio emission can be explained by the populations of the non-thermal electrons accelerated in the current sheets on the outer border of the magnetosphere of this fast-rotating magnetic star. We classify HR 5907 as another member of the growing class of strongly magnetic fast-rotating hot stars where the gyro-synchrotron emission mechanism efficiently operates in their magnetospheres. The new radio observations of HR 5907 are combined with archival X-ray data to study the physical condition of its magnetosphere. The X-ray spectra of HR 5907 show tentative evidence for the presence of non-thermal spectral component. We suggest that non-thermal X-rays originate a stellar X-ray aurora due to streams of non-thermal electrons impacting on the stellar surface. Taking advantage of the relation between the spectral indices of the X-ray power-law spectrum and the non-thermal electron energy distributions, we perform 3-D modelling of the radio emission for HR 5907. The wavelength-dependent radio light curves probe magnetospheric layers at different heights above the stellar surface. A detailed comparison between simulated and observed radio light curves leads us to conclude that the stellar magnetic field of HR 5907 is likely non-dipolar, providing further indirect evidence of the complex magnetic field topology of HR 5907.

  5. Experimental techniques; Techniques experimentales

    Energy Technology Data Exchange (ETDEWEB)

    Roussel-Chomaz, P. [GANIL CNRS/IN2P3, CEA/DSM, 14 - Caen (France)

    2007-07-01

    This lecture presents the experimental techniques, developed in the last 10 or 15 years, in order to perform a new class of experiments with exotic nuclei, where the reactions induced by these nuclei allow to get information on their structure. A brief review of the secondary beams production methods will be given, with some examples of facilities in operation or under project. The important developments performed recently on cryogenic targets will be presented. The different detection systems will be reviewed, both the beam detectors before the targets, and the many kind of detectors necessary to detect all outgoing particles after the reaction: magnetic spectrometer for the heavy fragment, detection systems for the target recoil nucleus, {gamma} detectors. Finally, several typical examples of experiments will be detailed, in order to illustrate the use of each detector either alone, or in coincidence with others. (author)

  6. Validation summary report for the 100-HR-3 Groundwater Round 9 Phase 1 and 2

    International Nuclear Information System (INIS)

    1996-02-01

    This report presents a summary of data validation results on groundwater samples collected for the 100-HR-3 Groundwater Round 9-Phase I and II Project. The analyses performed for this project were as follows: Metals--inductively coupled plasma (ICP) metals (filtered and unfiltered); General Chemistry--anions (fluoride, chloride, nitrate, nitrite, phosphate, and sulfate), turbidity, ammonia, nitrate+nitrite, and sulfide; and Radiochemistry--gross alpha, gross beta, technetium-99, tritium, and uranium-234/235/238. The objectives of this project were to validate sample detection limit as defined in the data validation procedures (WHC 1993). In addition, this report provides a summary of the data as defined by laboratory performance criteria and project-specific data quality objectives

  7. Complete genome sequence of Desulfohalobium retbaense type strain (HR100T)

    Energy Technology Data Exchange (ETDEWEB)

    Spring, Stefan [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany; Nolan, Matt [U.S. Department of Energy, Joint Genome Institute; Lapidus, Alla L. [U.S. Department of Energy, Joint Genome Institute; Glavina Del Rio, Tijana [U.S. Department of Energy, Joint Genome Institute; Copeland, A [U.S. Department of Energy, Joint Genome Institute; Tice, Hope [U.S. Department of Energy, Joint Genome Institute; Cheng, Jan-Fang [U.S. Department of Energy, Joint Genome Institute; Lucas, Susan [U.S. Department of Energy, Joint Genome Institute; Land, Miriam L [ORNL; Chen, Feng [U.S. Department of Energy, Joint Genome Institute; Bruce, David [Los Alamos National Laboratory (LANL); Goodwin, Lynne A. [Los Alamos National Laboratory (LANL); Pitluck, Sam [U.S. Department of Energy, Joint Genome Institute; Ivanova, N [U.S. Department of Energy, Joint Genome Institute; Mavromatis, K [U.S. Department of Energy, Joint Genome Institute; Mikhailova, Natalia [U.S. Department of Energy, Joint Genome Institute; Pati, Amrita [U.S. Department of Energy, Joint Genome Institute; Chen, Amy [U.S. Department of Energy, Joint Genome Institute; Palaniappan, Krishna [U.S. Department of Energy, Joint Genome Institute; Hauser, Loren John [ORNL; Chang, Yun-Juan [ORNL; Jeffries, Cynthia [Oak Ridge National Laboratory (ORNL); Munk, Christine [U.S. Department of Energy, Joint Genome Institute; Kiss, Hajnalka [Los Alamos National Laboratory (LANL); Chain, Patrick S. G. [Lawrence Livermore National Laboratory (LLNL); Han, Cliff [Los Alamos National Laboratory (LANL); Brettin, Thomas S [ORNL; Detter, J. Chris [U.S. Department of Energy, Joint Genome Institute; Schuler, Esther [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany; Goker, Markus [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany; Rohde, Manfred [HZI - Helmholtz Centre for Infection Research, Braunschweig, Germany; Bristow, James [U.S. Department of Energy, Joint Genome Institute; Eisen, Jonathan [U.S. Department of Energy, Joint Genome Institute; Markowitz, Victor [U.S. Department of Energy, Joint Genome Institute; Hugenholtz, Philip [U.S. Department of Energy, Joint Genome Institute; Kyrpides, Nikos C [U.S. Department of Energy, Joint Genome Institute; Klenk, Hans-Peter [DSMZ - German Collection of Microorganisms and Cell Cultures GmbH, Braunschweig, Germany

    2010-01-01

    Desulfohalobium retbaense (Ollivier et al. 1991) is the type species of the polyphyletic genus Desulfohalobium, which comprises, at the time of writing, two species and represents the family Desulfohalobiaceae within the Deltaproteobacteria. D. retbaense is a moderately halophilic sulfate-reducing bacterium, which can utilize H2 and a limited range of organic substrates, which are incompletely oxidized to acetate and CO2, for growth. The type strain HR100T was isolated from sediments of the hypersaline Retba Lake in Senegal. Here we describe the features of this organism, together with the complete genome sequence and annotation. This is the first completed genome sequence of a member of the family Desulfohalobiaceae. The 2,909,567 bp genome (one chromosome and a 45,263 bp plasmid) with its 2,552 protein-coding and 57 RNA genes is a part of the Genomic Encyclopedia of Bacteria and Archaea project.

  8. Geophysical investigation of the 116-H-1 liquid waste disposal trench, 100-HR-1 operable unit

    International Nuclear Information System (INIS)

    Bergstrom, K.A.; Mitchell, T.H.

    1996-04-01

    A geophysical investigation and data integration were conducted for the 116-H-1 Liquid Waste Disposal Trench, which is located in the 100-HR-1 Operable Unit. The 116-H-1 Liquid Waste Disposal Trench is also known as the 107-H Liquid Waste Disposal Trench, the 107-H Rupture Effluent Trench, and the 107-H Trench (Deford and Einan 1995). The trench was primarily used to hold effluent from the 107-H Retention Basin that had become radioactive from contact with ruptured fuel elements. The effluent may include debris from the ruptured fuel elements (Koop 1964). The 116-H-1 Liquid Waste Disposal Trench was also used to hold water and sludge from the 107-H Retention Basin during the basin's deactivation in 1965

  9. Dynamics of SARS-coronavirus HR2 domain in the prefusion and transition states

    Science.gov (United States)

    McReynolds, Susanna; Jiang, Shaokai; Rong, Lijun; Caffrey, Michael

    2009-12-01

    The envelope glycoproteins S1 and S2 of severe acute respiratory syndrome coronavirus (SARS-CoV) mediate viral entry by conformational change from a prefusion state to a postfusion state that enables fusion of the viral and target membranes. In this work we present the characterization of the dynamic properties of the SARS-CoV S2-HR2 domain (residues 1141-1193 of S) in the prefusion and newly discovered transition states by NMR 15N relaxation studies. The dynamic properties of the different states, which are stabilized under different experimental conditions, extend the current model of viral membrane fusion and give insight into the design of structure-based antagonists of SARS-CoV in particular, as well as other enveloped viruses such as HIV.

  10. Data validation report for the 100-HR-3 Operable Unit first quarter 1994 groundwater sampling data

    Energy Technology Data Exchange (ETDEWEB)

    Biggerstaff, R.L.

    1994-06-24

    Westinghouse-Hanford has requested that a minimum of 20% of the total number of Sample Delivery Groups be validated for the 100-HR-3 Operable Unit First Quarter 1994 Groundwater Sampling Investigation. Therefore, the data from the chemical analysis of twenty-four samples from this sampling event and their related quality assurance samples were reviewed and validated to verify that reported sample results were of sufficient quality to support decisions regarding remedial actions performed at this site. The samples were analyzed by Thermo-Analytic Laboratories (TMA) and Roy F. Weston Laboratories (WESTON) using US Environmental Protection Agency (EPA) CLP protocols. Sample analyses included: inorganics; and general chemical parameters. Forty-two samples were validated for radiochemical parameters by TMA and Teledyne.

  11. India's first 100,000 lbs/hr atmospheric bed boiler

    International Nuclear Information System (INIS)

    Mahajan, S.K.

    1991-01-01

    This paper covers the operating experience at the Petrochemical Complex of Hindustan Polymers, a Member Company of the UB Group, India, on the India's first 100,000 Lbs/hr atmospheric fluidized bed boiler supplied by Bharat Heavy Electricals Ltd., India. This atmospheric fluidized bed boiler is in operation for over 7 years with over 51,000 operating hours. The paper covers the details of onstream hours, actual thermal efficiency achieved, type of coal used and operational advantages of such boilers as per experience of Hindustan Polymers. Paper also highlights the maintenance and equipment problems as well as the developments which have taken place to overcome such problems. Details of experience in the operation of this boiler with baghouse system using abrasive and high ash coal are also covered

  12. GEMINI PLANET IMAGER SPECTROSCOPY OF THE HR 8799 PLANETS c AND d

    International Nuclear Information System (INIS)

    Ingraham, Patrick; Macintosh, Bruce; Marley, Mark S.; Saumon, Didier; Marois, Christian; Dunn, Jennifer; Erikson, Darren; Barman, Travis; Bauman, Brian; Burrows, Adam; Chilcote, Jeffrey K.; Fitzgerald, Michael P.; De Rosa, Robert J.; Dillon, Daren; Gavel, Donald; Doyon, René; Goodsell, Stephen J.; Hartung, Markus; Hibon, Pascale; Graham, James R.

    2014-01-01

    During the first-light run of the Gemini Planet Imager we obtained K-band spectra of exoplanets HR 8799 c and d. Analysis of the spectra indicates that planet d may be warmer than planet c. Comparisons to recent patchy cloud models and previously obtained observations over multiple wavelengths confirm that thick clouds combined with horizontal variation in the cloud cover generally reproduce the planets' spectral energy distributions. When combined with the 3 to 4 μm photometric data points, the observations provide strong constraints on the atmospheric methane content for both planets. The data also provide further evidence that future modeling efforts must include cloud opacity, possibly including cloud holes, disequilibrium chemistry, and super-solar metallicity

  13. Preparation of dielectrics HR mirrors from colloidal oxide suspensions containing organic polymer binders

    International Nuclear Information System (INIS)

    Thomas, I.M.

    1994-01-01

    Colloidal suspensions of oxides have been used to prepare dielectric HR (high reflective) mirrors, specifically for high power fusion case applications, on substrates up to 38 cm square using a meniscus coater. These coatings consist of porous quarterwave layers of alternating high and low refractive index oxides. Silica was used as the low index oxide and AlOOH, ZrO 2 , or HfO 2 as the high index material. Coatings were weak because of low particle-to-particle adhesion. Use of organic polymer binders in the high index component was found to increase strength, thereby improving the laser damage threshold and also reducing the number of layers required for 99% reflection due to increased refractive index

  14. Data validation report for the 100-HR-3 Operable Unit first quarter 1994 groundwater sampling data

    International Nuclear Information System (INIS)

    Biggerstaff, R.L.

    1994-01-01

    Westinghouse-Hanford has requested that a minimum of 20% of the total number of Sample Delivery Groups be validated for the 100-HR-3 Operable Unit First Quarter 1994 Groundwater Sampling Investigation. Therefore, the data from the chemical analysis of twenty-four samples from this sampling event and their related quality assurance samples were reviewed and validated to verify that reported sample results were of sufficient quality to support decisions regarding remedial actions performed at this site. The samples were analyzed by Thermo-Analytic Laboratories (TMA) and Roy F. Weston Laboratories (WESTON) using US Environmental Protection Agency (EPA) CLP protocols. Sample analyses included: inorganics; and general chemical parameters. Forty-two samples were validated for radiochemical parameters by TMA and Teledyne

  15. Performance evaluation of the whole-body PET scanner ECAT EXACT HR+

    International Nuclear Information System (INIS)

    Adam, L.E.; Zaers, J.; Ostertag, H.; Trojan, H.

    1996-01-01

    The performance parameters of the whole-body PET scanner ECAT EXACT HR + were determined following the standard proposed by the International Electrotechnical Commission (IEC). The tests were expanded by some measurements concerning the accuracy of the correction algorithms and the geometric fidelity of the reconstructed images. The scanner consists of 32 rings, each with 576 BGO detectors (4.05 x 4.39 x 30 mm 3 ) covering an axial field-of-view of 15.5 cm and a patient port of 56.2 cm. The transaxial resolution in the 2D (3D) mode is 4.5 (4.3) mm at the center. It increases to 8.9 (8.3) mm radially and to 5.8 (5.2) mm tangentially at a radial distance of r = 20 cm. The average axial resolution varies between 4.9 (4.1) mm FWHM at the center and 8.8 (8.1) mm at r = 20 cm. The system sensitivity for true events is 5.85 (26.4) cps/Bq/ml (measured with a 20 cm cylinder phantom). The 50% dead-time losses where reached for a true event count rate of 286 (500) kcps at an activity concentration of 74 (25) kBq/ml. The system scatter fraction is 0.24 (0.35). The correction algorithms work reliable, except for the 3D attenuation correction. The ECAT EXACT HR + has a good and nearly isotropic spatial resolution. Due to the small detector elements, however, it has a low slice sensitivity which is a limiting factor for image quality

  16. HR Excellence in Research as an attribute of scientific institutions’ competitiveness

    Directory of Open Access Journals (Sweden)

    Jarosławska-Sobór Sylwia

    2017-03-01

    Full Text Available What plays a major role in the process of building the competitiveness of an organization is not just the ability to adapt to the changing conditions in the environment, but also acquiring characteristics distinguishing it, which make it possible to keep, or improve its position on the market. What may be such a handicap for a scientific unit is the HR Excellence in Research (HRE logo, which is awarded by the European Commission under the strategy “Human Resources Strategy for Researchers” (HRS4R. It is awarded to scientific institutions, which implement the rules of the „European Charter for Researchers” and the „Code of Conduct for the Recruitment of Researchers”, and thanks to this create a friendly work environment and opportunities for development. In 2015 Central Mining Institute (GIG took steps aimed at getting the HR Excellence in Research logo, which is supposed to boost the attractiveness of the institute for scientists and contribute to further development of science and achieving a better position on the market. In the article the results of an internal analysis, which includes research on the opinions of scientific and research employees of GIG concerning the existing practices and rules governing research at the institute, are discussed. As a result of the research a Report together with an Action Plan were drawn up. They are supposed to support the creation of a friendly environment for scientific work and transparent rules for recruiting scientific employees. Also, the article highlights the most important challenges which the institute has to face in order to fully implement the guidelines of HRE, which stimulate economic and personal development.

  17. Pilot-scale treatability test plan for the 100-HR-3 operable unit

    International Nuclear Information System (INIS)

    1994-08-01

    This document presents the treatability test plan for pilot-scale pump-and-treat testing at the 100-HR-3 Operable Unit. The test will be conducted in fulfillment of interim Milestone M-15-06E to begin pilot-scale pump-and-treat operations by August 1994. The scope of the test was determined based on the results of lab/bench-scale tests (WHC 1993a) conducted in fulfillment of Milestone M-15-06B. These milestones were established per agreement between the U.S. Department of Energy (DOE), the Washington State Department of Ecology and the U.S. Environmental Protection Agency (EPA), and documented on Hanford Federal of Ecology Facility Agreement and Consent Order Change Control Form M-15-93-02. This test plan discusses a pilot-scale pump-and-treat test for the chromium plume associated with the D Reactor portion of the 100-HR-3 Operable Unit. Data will be collected during the pilot test to assess the effectiveness, operating parameters, and resource needs of the ion exchange (IX) pump-and-treat system. The test will provide information to assess the ability to remove contaminants by extracting groundwater from wells and treating extracted groundwater using IX. Bench-scale tests were conducted previously in which chromium VI was identified as the primary contaminant of concern in the 100-D reactor plume. The DOWEX 21K trademark resin was recommended for pilot-scale testing of an IX pump-and-treat system. The bench-scale test demonstrated that the system could remove chromium VI from groundwater to concentrations less than 50 ppb. The test also identified process parameters to monitor during pilot-scale testing. Water will be re-injected into the plume using wells outside the zone of influence and upgradient of the extraction well

  18. DEBRIS DISTRIBUTION IN HD 95086—A YOUNG ANALOG OF HR 8799

    International Nuclear Information System (INIS)

    Su, Kate Y. L.; Smith, Paul S.; Rieke, George H.; Morrison, Sarah; Malhotra, Renu; Balog, Zoltan

    2015-01-01

    HD 95086 is a young early-type star that hosts (1) a 5 M J planet at the projected distance of 56 AU revealed by direct imaging, and (2) a prominent debris disk. Here we report the detection of 69 μm crystalline olivine feature from the disk using the Spitzer/MIPS-SED data covering 55-95 μm. Due to the low resolution of the MIPS-SED mode, this feature is not spectrally resolved, but is consistent with the emission from crystalline forsterite contributing ∼5% of the total dust mass. We also present detailed analysis of the disk spectral energy distribution and re-analysis of resolved images obtained by Herschel. Our results suggest that the debris structure around HD 95086 consists of a warm (∼175 K) belt, a cold (∼55 K) disk, and an extended disk halo (up to ∼800 AU), and is very similar to that of HR 8799. We compare the properties of the three debris components, and suggest that HD 95086 is a young analog of HR 8799. We further investigate and constrain single-planet, two-planet, three-planet, and four-planet architectures that can account for the observed debris structure and are compatible with dynamical stability constraints. We find that equal-mass four-planet configurations of geometrically spaced orbits, with each planet of mass ∼ 5 M J , could maintain the gap between the warm and cold debris belts, and also be just marginally stable for timescales comparable to the age of the system

  19. DEBRIS DISTRIBUTION IN HD 95086—A YOUNG ANALOG OF HR 8799

    Energy Technology Data Exchange (ETDEWEB)

    Su, Kate Y. L.; Smith, Paul S.; Rieke, George H. [Steward Observatory, University of Arizona, 933 N Cherry Ave., Tucson, AZ 85721 (United States); Morrison, Sarah; Malhotra, Renu [Lunar and Planetary Laboratory, University of Arizona, Tucson, AZ 85721 (United States); Balog, Zoltan, E-mail: ksu@as.arizona.edu [Max-Planck-Institut für Astronomie, Königstuhl 17 D-69117, Heidelberg (Germany)

    2015-02-01

    HD 95086 is a young early-type star that hosts (1) a 5 M{sub J} planet at the projected distance of 56 AU revealed by direct imaging, and (2) a prominent debris disk. Here we report the detection of 69 μm crystalline olivine feature from the disk using the Spitzer/MIPS-SED data covering 55-95 μm. Due to the low resolution of the MIPS-SED mode, this feature is not spectrally resolved, but is consistent with the emission from crystalline forsterite contributing ∼5% of the total dust mass. We also present detailed analysis of the disk spectral energy distribution and re-analysis of resolved images obtained by Herschel. Our results suggest that the debris structure around HD 95086 consists of a warm (∼175 K) belt, a cold (∼55 K) disk, and an extended disk halo (up to ∼800 AU), and is very similar to that of HR 8799. We compare the properties of the three debris components, and suggest that HD 95086 is a young analog of HR 8799. We further investigate and constrain single-planet, two-planet, three-planet, and four-planet architectures that can account for the observed debris structure and are compatible with dynamical stability constraints. We find that equal-mass four-planet configurations of geometrically spaced orbits, with each planet of mass ∼ 5 M{sub J} , could maintain the gap between the warm and cold debris belts, and also be just marginally stable for timescales comparable to the age of the system.

  20. Limited field investigation report for the 100-HR-1 Operable Unit

    International Nuclear Information System (INIS)

    1994-08-01

    This limited field investigation (LFI) report summarizes the data collection and analysis activities conducted during the 100-HR-1 Source Operable Unit LFI and the associated qualitative risk assessment (QRA) (WHC 1993a), and makes recommendations on the continued candidacy of high-priority sites for interim remedial measures (IRM). The results and recommendations presented in this report are generally independent of future land use scenarios. A LFI Report is required, in accordance with the HPPS, when waste sites are to be considered for IRMs. The LFI is an integral part of the remedial investigation/feasibility study (RI/FS) or Resource Conservation and Recovery Act (RCRA) facility investigation/corrective measures study (RFI/CMS) and process and functions as a focused RI or RFI for selection of IRMs. The purpose of the report is to identify those sites that are recommended to remain as candidates for IRMs, provide a preliminary summary of site characterization studies, refine the conceptual model as needed, identify contaminant- and location-specific applicable or relevant and appropriate requirements (ARA), and provide a qualitative assessment of the risks associated with the sites. This assessment includes consideration of whether contaminant concentrations pose an unacceptable risk that warrants action through IRMs. The 100-HR-1 unit encompasses approximately 100 acres adjacent to the Columbia River shoreline. It contains waste units associated with the original plant facilities constructed to support the H Reactor. The area also contains evaporation basins which received liquid process wastes and nonroutine deposits of chemical wastes from the 300 Area, where fuel elements for the N Reactor were produced

  1. The hr locus and the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in newborn mice

    Energy Technology Data Exchange (ETDEWEB)

    Connor, M.J. (Div. of Dermatology, Dept. of Medicine, UCLA School of Medicine, Los Angeles, CA (United States) Research Service, Veterans Administration West Los Angeles Medical Center, Los Angeles, CA (United States)); Puhvel, S.M. (Div. of Dermatology, Dept. of Medicine, UCLA School of Medicine, Los Angeles, CA (United States) Research Service, Veterans Administration West Los Angeles Medical Center, Los Angeles, CA (United States)); Sakamoto, M. (Div. of Dermatology, Dept. of Medicine, UCLA School of Medicine, Los Angeles, CA (United States) Research Service, Veterans Administration West Los Angeles Medical Center, Los Angeles, CA (United States)); Nanthur, J. (Div. of Dermatology, Dept. of Medicine, UCLA School of Medicine, Los Angeles, CA (United States) Research Service, Veterans Administration West Los Angeles Medical Center, Los Angeles, CA (United States))

    1994-12-01

    In mice, the recessive mutation hairless (hr) controls the cutaneous response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) but its influence on TCDD's systemic toxicity is unclear. To clarify this, we compared the effects of lactational TCDD exposure on standardized litters of newborn HRS/J mice homozygous for either hr or + that were fostered by haired dams exposed to 0, 6, 8 or 12 [mu]g TCDD/kg body weight on postnatal day 0. At 12 [mu]g/kg, TCDD was lethal to both haired and hairless pups. At the lower doses (6 and 8 [mu]g/kg) the survival of hr/hr pups was significantly lower than +/+ pups. Affected pups succumbed following a 1 to 2-day period of cachexia and wasting. As has been reported for other mouse strains, TCDD exposure impacted on their neonatal development and lessened the time to eye opening for both haired and hairless pups. However, the hairless animals were affected at lower doses than were the haired. The results of this study document that the hr/hr genotype does influence the systemic toxicity of TCDD in mice. (orig.)

  2. The hr locus and the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in newborn mice

    Energy Technology Data Exchange (ETDEWEB)

    Connor, M J [Div. of Dermatology, Dept. of Medicine, UCLA School of Medicine, Los Angeles, CA (United States) Research Service, Veterans Administration West Los Angeles Medical Center, Los Angeles, CA (United States); Puhvel, S M [Div. of Dermatology, Dept. of Medicine, UCLA School of Medicine, Los Angeles, CA (United States) Research Service, Veterans Administration West Los Angeles Medical Center, Los Angeles, CA (United States); Sakamoto, M [Div. of Dermatology, Dept. of Medicine, UCLA School of Medicine, Los Angeles, CA (United States) Research Service, Veterans Administration West Los Angeles Medical Center, Los Angeles, CA (United States); Nanthur, J [Div. of Dermatology, Dept. of Medicine, UCLA School of Medicine, Los Angeles, CA (United States) Research Service, Veterans Administration West Los Angeles Medical Center, Los Angeles, CA (United States)

    1994-12-01

    In mice, the recessive mutation hairless (hr) controls the cutaneous response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) but its influence on TCDD's systemic toxicity is unclear. To clarify this, we compared the effects of lactational TCDD exposure on standardized litters of newborn HRS/J mice homozygous for either hr or + that were fostered by haired dams exposed to 0, 6, 8 or 12 [mu]g TCDD/kg body weight on postnatal day 0. At 12 [mu]g/kg, TCDD was lethal to both haired and hairless pups. At the lower doses (6 and 8 [mu]g/kg) the survival of hr/hr pups was significantly lower than +/+ pups. Affected pups succumbed following a 1 to 2-day period of cachexia and wasting. As has been reported for other mouse strains, TCDD exposure impacted on their neonatal development and lessened the time to eye opening for both haired and hairless pups. However, the hairless animals were affected at lower doses than were the haired. The results of this study document that the hr/hr genotype does influence the systemic toxicity of TCDD in mice. (orig.)

  3. Transgenic Cotton Plants Expressing the HaHR3 Gene Conferred Enhanced Resistance to Helicoverpa armigera and Improved Cotton Yield.

    Science.gov (United States)

    Han, Qiang; Wang, Zhenzhen; He, Yunxin; Xiong, Yehui; Lv, Shun; Li, Shupeng; Zhang, Zhigang; Qiu, Dewen; Zeng, Hongmei

    2017-08-30

    RNA interference (RNAi) has been developed as an efficient technology. RNAi insect-resistant transgenic plants expressing double-stranded RNA (dsRNA) that is ingested into insects to silence target genes can affect the viability of these pests or even lead to their death. HaHR3 , a molt-regulating transcription factor gene, was previously selected as a target expressed in bacteria and tobacco plants to control Helicoverpa armigera by RNAi technology. In this work, we selected the dsRNA- HaHR3 fragment to silence HaHR3 in cotton bollworm for plant mediated-RNAi research. A total of 19 transgenic cotton lines expressing HaHR3 were successfully cultivated, and seven generated lines were used to perform feeding bioassays. Transgenic cotton plants expressing ds HaHR3 were shown to induce high larval mortality and deformities of pupation and adult eclosion when used to feed the newly hatched larvae, and 3rd and 5th instar larvae of H. armigera . Moreover, HaHR3 transgenic cotton also demonstrated an improved cotton yield when compared with controls.

  4. Angiotensin (1-7) ameliorates the structural and biochemical alterations of ovariectomy-induced osteoporosis in rats via activation of ACE-2/Mas receptor axis.

    Science.gov (United States)

    Abuohashish, Hatem M; Ahmed, Mohammed M; Sabry, Dina; Khattab, Mahmoud M; Al-Rejaie, Salim S

    2017-05-23

    The local and systemic renin angiotensin system (RAS) influences the skeletal system micro-structure and metabolism. Studies suggested angiotensin 1-7 (Ang(1-7)) as the beneficial RAS molecule via Mas receptor activation. This study examines the function of Ang(1-7) in bone micro-architecture and metabolism in an ovariectomized (OVX) rodent model of osteoporosis. OVX rats showed structural and bone metabolic degeneration in parallel with suppressed expressions of the angiotensin converting enzyme-2 (ACE-2)/Ang(1-7)/Mas components. The infusion of Ang(1-7) markedly alleviated the altered bone metabolism and significantly enhanced both trabecular (metaphyseal) and cortical (metaphyseal-diaphyseal) morphometry. Urinary and bones minerals were also improved in OVX rats by Ang(1-7). The infusion of the heptapeptide enhanced ACE-2/Mas receptor expressions, while down-regulated AngII, ACE, and AngII type-1 receptor (AT1R) in OVX animals. Moreover, Ang(1-7) markedly improved osteoprotegerin (OPG) and lowered receptor activator NF-κB ligand (RANKL) expressions. The defensive properties of Ang(1-7) on bone metabolism, structure and minerals were considerably eradicated after blockage of Mas receptor with A-779. Ang(1-7)-induced up-regulated ACE-2/Ang(1-7)/Mas cascade and OPG expressions were abolished and the expressions of ACE/AngII/AT1R and RANKL were provoked by A-779. These findings shows for the first time the novel valuable therapeutic role of Ang(1-7) on bone health and metabolism through the ACE-2/Mas cascade.

  5. Radiation doses during chest examinations using dose modulation techniques in multislice CT scanner

    OpenAIRE

    Livingstone Roshan; Pradip Joe; Dinakran Paul; Srikanth B

    2010-01-01

    Objective: To evaluate the radiation dose and image quality using a manual protocol and dose modulation techniques in a 6-slice CT scanner. Materials and Methods: Two hundred and twenty-one patients who underwent contrast-enhanced CT of the chest were included in the study. For the manual protocol settings, constant tube potential (kV) and tube current-time product (mAs) of 140 kV and 120 mAs, respectively, were used. The angular and z-axis dose modulation techniques utilized a constant tu...

  6. Electromagnetic Scattering Analysis of Coated Conductors With Edges Using the Method of Auxiliary Sources (MAS) in Conjunction With the Standard Impedance Boundary Condition (SIBC)

    DEFF Research Database (Denmark)

    Anastassiu, H.T.; D.I.Kaklamani, H.T.; Economou, D.P.

    2002-01-01

    A novel combination of the method of auxiliary sources (MAS) and the standard impedance boundary condition (SIBC) is employed in the analysis of transverse magnetic (TM) plane wave scattering from infinite, coated, perfectly conducting cylinders with square cross sections. The scatterer is initia......A novel combination of the method of auxiliary sources (MAS) and the standard impedance boundary condition (SIBC) is employed in the analysis of transverse magnetic (TM) plane wave scattering from infinite, coated, perfectly conducting cylinders with square cross sections. The scatterer...

  7. 阴道滴虫与宫颈HR-HPV感染及宫颈癌发生的相关性%Association about Trichomonas, HR-HPV Infection and Cervical Carcinoma

    Institute of Scientific and Technical Information of China (English)

    李旻; 郭会芹; 陈凤; 曹箭; 李中林; 张询; 潘秦镜

    2007-01-01

    目的 探讨阴道滴虫是否能增加高危人乳头瘤病毒(HR-HPV)感染和宫颈癌发生的危险.方法 对受检者进行液基细胞学检查和HR-HPV DNA检测,并在细胞学诊断中记录是否存在滴虫.对所有细胞学诊断非典型鳞状细胞(ASC)及以上病变、HR-HPV DNA阳性病例和部分细胞学阴性及HR-HPV DNA阴性病例进行阴道镜检查及活检.分别比较滴虫在HR-HPV DNA阳性组和阴性组、细胞学及组织学各级诊断中的存在率.结果 在13 024例受检者中有1 687例(12.95%)涂片中有滴虫.滴虫存在率在HR-HPV DNA阳性组与阴性组中无显著统计学差异(P>0.05),在细胞学阴性病例组显著高于鳞状上皮内病变组(P<0.05),在组织学阴性病例组显著高于在≥CIN2病例组(P<0.05).结论 滴虫的存在不增加HR-HPV感染率,也不增加宫颈癌发生的危险.

  8. Oral nanotherapeutics: Redox nanoparticles attenuate ultraviolet B radiation-induced skin inflammatory disorders in Kud:Hr- hairless mice.

    Science.gov (United States)

    Feliciano, Chitho P; Nagasaki, Yukio

    2017-10-01

    The active participation of an anti-inflammatory drug in the biological pathways of inflammation is crucial for the achievement of beneficial and therapeutic effects. This study demonstrated the development of redox nanoparticles that can circulate in the blood at significantly high levels, thus increasing their efficacy as an oral treatment against the deleterious effects of reactive oxygen species (ROS) in an in vivo inflammatory skin model. To confirm the blood bioavailability of the nanoparticles, mice were injected with the nanoparticles solution (RNP N ) via oral gavage. Using electron spin resonance and radioactive labeling techniques, the blood circulation of the redox polymer that forms the nanoparticles was confirmed 24 h after oral administration. This contrasted with its low molecular weight counterpart (NH 2 -TEMPO), which peaked 15 min post injection and was found to be cleared rapidly within minutes after the peak. We then tested its efficacy in the inflammatory skin model. Kud:Hr-hairless mice were irradiated with UVB (302 nm) to induce skin damage and inflammation. Throughout the entire period of UVB irradiation, RNP N was administered to mice by free drinking. NH 2 -TEMPO was used as the control. The results showed that oral supplementation of RNP N significantly improved the therapeutic effects of the core nitroxide radical compared with its low molecular weight counterpart. Furthermore, RNP N significantly reduced UVB-induced skin aging, epidermal thickening, edema, erythema, skin lesions, and various pathological skin inflammatory disorders in vivo. From the obtained data, we concluded that the use of long-circulating redox nanoparticles (RNP N ) provided an effective treatment against the damaging effects of excessive ROS in the body. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. Efektifitas Nannochloropsis sp. terhadap sistem imun non-spesifik ikan mas Cyprinus carpio yang diinfeksi Virus Herpes

    Directory of Open Access Journals (Sweden)

    Arafik Lamadi

    2017-11-01

    Full Text Available The aim of this research was to determine the effect of Nannochlorpsisis sp. against the common carp (Cyprinus carpio leukocyte profile, infected with Koi Hepesvirus (KHV. The  descriptive observational method wa used in this study. This research was conducted for 4 weeks, using common carp length 12±0,3 cm as many as 7 fish. The tested experiment was P1: without infested by Nannochlorpsisis sp. and KH; P2: Infested by  Nannochlorpsisis sp. and without KHV infected; P3: Infected by Nannochloropsis sp. and KHV; P4;  Not infected by Nannochlorpsisis sp. and  infected by KHV. Evey tratment in three replications. The results showed that the highest total leukocyte was obtained in P3 (37.600 cells/ml, followed by  P4 (29.650 cells / ml, P2 (28,500 cells / ml and P1 (21,150 cells / ml. Leukocyte differentiation test on P1 (neutrophil 6.2%, lymphocyte 68.0%, monocyte 17.0%, P2 (neutrophil 6.6%, lymphocyte 72.3%, monocyte 18.3%, P3 (neutrophil 7.9%, lymphocyte 66.1%, monocytes 24.3%, P4 (neutrophils 11.2%, lymphocytes 57.6%, monocytes 37.6%. The higher survivla rate was recorded in P2 (100%. It is concluded that  Nannochloropsis sp. can enhance the common carp immune sytem. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian Nannochlorpsis sp. terhadap profil leukosit ikan mas (Cyprinus carpio yang terinfeksi Koi Herves Virus (KHV. Penelitian ini menggunakan metode deskriptif observasional dengan membandingkan hasil pada perlakuan 1 P1: (tanpa pemberian Nannochlorpsis sp. dan tidak diinfeksi KHV, 2 P2 (diberikan Nannochlorpsis sp dan tanpa diinfeksi KHV, 3 P3 (diberikan Nannochlorpsisis sp dan diinfeksi KHV, 4 P4 (tanpa pemberian Nannochlorpsis sp. dan diinfeksi KHV, masing-masing perlakukan 3 kali ulangan. Penelitian ini dilakukan selama 4 minggu dengan menggunakan Ikan mas berukuran 12±0,3  cm sebanyak 120 ekor. Hasil perhitungan total leukosit tertinggi diperoleh pada P3 (37.600 sel/ml, selanjutnya berturut-turut  P4 (29.650  sel

  10. PAPARAN SENG DI PERAIRAN KALIGARANG TERHADAP EKSPRESI Zn-THIONEIN DAN KONSENTRASI SENG PADA HATI IKAN MAS

    Directory of Open Access Journals (Sweden)

    NK Dewi

    2013-07-01

    Full Text Available Penelitian bertujuan mengetahui paparan seng (Zn di perairan Kaligarang terhadap ekspresi Zn-thionein dan konsentrasi seng pada hati ikan mas (Cyprinus carpio L. Sebanyak 200 ekor ikan dibagi menjadi dua kelompok, masing-masing kelompok 100 ekor. Kelompok kontrol dipelihara di kolam ikan di Balai Benih Ikan Kabupaten Semarang, sedangkan kelompok perlakuan dipelihara pada karamba jaring apung di bagian hilir sungai Kaligarang. Setiap minggu sampel ikan diambil masing-masing lima ekor dari kedua kelompok secara acak untuk diambil organ hatinya dan dianalisis konsentrasi seng dan Zn-thionein. Ikan pada kedua kelompok dipelihara hingga Zn-thionein muncul pada hati ikan. Metallothionein diisolasi dari hati ikan dan dianalisis menggunakan metode High-Performance Liquid Chromatography, dengan larutan standar seng. Setiap satu minggu sekali, konsentrasi seng terlarut pada sampel air dari kedua kelompok diukur dengan metode Atomic Absorption Spectroscopy hingga Zn-thionein muncul. Hasil penelitian menunjukkan bahwa konsentrasi seng yang terlarut dalam air sungai Kaligarang adalah 0,078 mg/l, lebih tinggi dari nilai baku mutu air kelas I (0,05 mg/l. Rata-rata konsentrasi seng yang terabsorbi oleh hati ikan mas pada minggu ke-6 adalah 0,025868 mg/l, lebih rendah dari batas maksimum cemaran seng (100 mg/kg. Rata-rata konsentrasi seng pada hati ikan sebesar 0,025868 µg/g dapat menginduksi munculnya Zn-thionein pada hati ikan mas yang hidup di perairan Kaligarang pada minggu ke-6 perlakuan. The research aims to find concentration of dissolved zinc in the water of Kaligarang River and absorbed zinc concentration inside the liver of carp, also to analyze zinc exposure in Kaligarang River toward Zn-thionein induction inside the liver of carp. The concentration of dissolved zinc was measured using Atomic Absorption Spectroscopy method until Zn-thionein emerges. Metallothionein was isolated from the liver of carp and analyzed using High-Performance Liquid

  11. Tagging of blast resistance gene(s) to DNA markers and marker-assisted selection (MAS) in rice improvement

    International Nuclear Information System (INIS)

    Zhuang, J.Y.; Lu, J.; Qian, H.R.; Lin, H.X.; Zheng, K.L.

    1998-01-01

    This paper reports progress made on the tagging of blast resistance gene(s) to DNA markers and on the initiation of marker-assisted selection (MAS) for blast resistance in rice improvement. A pair of near isogenic lines, K8OR and K79S, were developed using a Chinese landrace Hong-jiao-zhan as the resistance donor. Ten putatively positive markers were identified by screening 177 mapped DNA markers. Using the F 2 population of 143 plants and the derived F 3 lines, three Restriction Fragment Length Polymorphism (RFLP) markers (RG81, RG869 and RZ397) on chromosome 12 of rice were identified to be closely linked to the blast resistance gene Pi-12(t). The genetic distance between Pi-12(t) and the closest marker RG869 was 5.1 cM. By employing the bulk segregant analysis (BSA) procedure, six of 199 arbitrary primers were found to produce positive Randomly Amplified Polymorphic DNA (RAPD) bands. Tight linkage between Pi-12(t) and three RAPD bands, each from a different primer, was confirmed after amplification of DNA of all F 2 individuals. Two fragments were cloned and sequenced, and two sequence characterised amplified re-ion (SCAR) markers were established. In two other F 3 populations, Xian-feng I/Tetep and Xian-feng, 1/Hong-jiao-zhan, the blast resistance was found to be controlled by interactions of two or more genes. One resistance gene was located in the vicinity of RG81 in both populations. Work to identify other gene(s) is currently under way. Marker assisted selection for blast resistance was initiated. Crosses were made between elite varieties and blast resistance donors to develop populations for DNA marker-assisted selection of blast resistance. In addition, 48 varieties widely used in current rice breeding programs were provided by rice breeders. DNA marker-based polymorphism among, these varieties and resistance donors were analysed to produce a database for future MAS program. (author)

  12. Molecular absorption spectrometry in flames and furnaces: A review

    Energy Technology Data Exchange (ETDEWEB)

    Butcher, David J., E-mail: butcher@email.wcu.edu

    2013-12-04

    Graphical abstract: -- Highlights: •Theory and analytical considerations for molecular absorption spectrometry (MAS). •Critical review of low resolution MAS. •Critical review of the analytical performance of high-resolution continuum source (HR-CS) flame MAS. •Critical review of the analytical performance of HR-CS graphite furnace MAS. •Current status of HR-CS MAS and its future prospects for elemental analysis. -- Abstract: Molecular absorption spectrometry (MAS), originally developed in the 1970s, is a technique to determine non-metals in flames and graphite furnaces by monitoring the absorbance of diatomic molecules. Early studies employed low resolution instruments designed for line source atomic absorption, which provided a limited choice of analytical wavelengths, insufficient spectral resolution, and spectral interferences. However, the development of high-resolution continuum source atomic absorption spectrometry (HR-CS AAS) instrumentation has allowed the analysis of challenging samples for non-metals as well as some difficult elements to determine by AAS, such as aluminum and phosphorus. In this review, theory and analytical considerations for MAS are discussed. The principles and limitations of low resolution MAS are described, along with its applications. HR-CS AAS instrumentation is reviewed, emphasizing performance characteristics most relevant for MAS. Applications of flame and HR-CS GFMAS are reviewed, highlighting the most significant work to date. The paper concludes with an evaluation of the enhanced analytical capabilities provided by HR-CS MAS.

  13. Ceļu satiksmes drošības direkcijas (CSDD) sociālo reklāmas kampaņu klipu semiotiskā analīze (2003. - 2013.)

    OpenAIRE

    Lapinska, Ginta

    2014-01-01

    Bakalaura darba tēma ir „Ceļu satiksmes drošības direkcijas (CSDD) sociālo reklāmas kampaņu klipu semiotiskā analīze (2003. - 2013.)”. CSDD reklāmas gadu gaitā ir pārliecinājušas reklāmas industriju un auditoriju, tāpēc būtiski ir noskaidrot, kādi ir izmantotie semiotiskie elementi un kā to izmantojums gadu gaitā ir mainījies. Darba mērķis ir izpētīt vienojošos semiotiskos elementus CSDD reklāmas kampaņu klipos no 2003.-2013. gadam. Teorētiskajā daļā aplūkotas tēmas: reklāmas, kampaņas ...

  14. VLT/SPHERE robust astrometry of the HR8799 planets at milliarcsecond-level accuracy. Orbital architecture analysis with PyAstrOFit

    Science.gov (United States)

    Wertz, O.; Absil, O.; Gómez González, C. A.; Milli, J.; Girard, J. H.; Mawet, D.; Pueyo, L.

    2017-02-01

    Context. HR8799 is orbited by at least four giant planets, making it a prime target for the recently commissioned Spectro-Polarimetric High-contrast Exoplanet REsearch (VLT/SPHERE). As such, it was observed on five consecutive nights during the SPHERE science verification in December 2014. Aims: We aim to take full advantage of the SPHERE capabilities to derive accurate astrometric measurements based on H-band images acquired with the Infra-Red Dual-band Imaging and Spectroscopy (IRDIS) subsystem, and to explore the ultimate astrometric performance of SPHERE in this observing mode. We also aim to present a detailed analysis of the orbital parameters for the four planets. Methods: We performed thorough post-processing of the IRDIS images with the Vortex Imaging Processing (VIP) package to derive a robust astrometric measurement for the four planets. This includes the identification and careful evaluation of the different contributions to the error budget, including systematic errors. Combining our astrometric measurements with the ones previously published in the literature, we constrain the orbital parameters of the four planets using PyAstrOFit, our new open-source python package dedicated to orbital fitting using Bayesian inference with Monte-Carlo Markov Chain sampling. Results: We report the astrometric positions for epoch 2014.93 with an accuracy down to 2.0 mas, mainly limited by the astrometric calibration of IRDIS. For each planet, we derive the posterior probability density functions for the six Keplerian elements and identify sets of highly probable orbits. For planet d, there is clear evidence for nonzero eccentricity (e 0.35), without completely excluding solutions with smaller eccentricities. The three other planets are consistent with circular orbits, although their probability distributions spread beyond e = 0.2, and show a peak at e ≃ 0.1 for planet e. The four planets have consistent inclinations of approximately 30° with respect to the sky

  15. Cooperating systems: Layered MAS

    Science.gov (United States)

    Rochowiak, Daniel

    1990-01-01

    Distributed intelligent systems can be distinguished by the models that they use. The model developed focuses on layered multiagent system conceived of as a bureaucracy in which a distributed data base serves as a central means of communication. The various generic bureaus of such a system is described and a basic vocabulary for such systems is presented. In presenting the bureaus and vocabularies, special attention is given to the sorts of reasonings that are appropriate. A bureaucratic model has a hierarchy of master system and work group that organizes E agents and B agents. The master system provides the administrative services and support facilities for the work groups.

  16. Editorial. Un paso mas

    Directory of Open Access Journals (Sweden)

    Jaime Fandiño Franky

    2014-04-01

    Full Text Available La Fundación Premio Nacional de Epilepsia Margaret Merz de Fandiño, en sus tres convocatorias, ha motivado a los grupos empeñados en el estudio del sistema nervioso para pensar en profundizar en los misterios de la ciencia.

  17. El universo mas pequeno

    CERN Multimedia

    Rivera, Alicia

    2007-01-01

    The future of the exploration of the microcosmos will be in a ring formed by more than 8'000 magnets. With the new great particle acceleator LHC, nearly finished in Geneva, scientists will see how the universe was created just after the Big Bang. (3 pages with photos)

  18. Structural investigations of borosilicate glasses containing MoO{sub 3} by MAS NMR and Raman spectroscopies

    Energy Technology Data Exchange (ETDEWEB)

    Caurant, D., E-mail: daniel-caurant@enscp.f [Laboratoire de Chimie de la Matiere Condensee de Paris, UMR-CNRS 7574, Ecole Nationale Superieure de Chimie de Paris (ENSCP, ParisTech), 11 rue Pierre et Marie Curie, 75231 Paris (France); Majerus, O.; Fadel, E.; Quintas, A. [Laboratoire de Chimie de la Matiere Condensee de Paris, UMR-CNRS 7574, Ecole Nationale Superieure de Chimie de Paris (ENSCP, ParisTech), 11 rue Pierre et Marie Curie, 75231 Paris (France); Gervais, C. [Laboratoire de Chimie de la Matiere Condensee de Paris, UMR-CNRS 7574, Universite Pierre et Marie Curie, 75252 Paris (France); Charpentier, T. [CEA, IRAMIS, Service Interdisciplinaire sur les Systemes Moleculaires et Materiaux, CEA Saclay, 91191 Gif-sur-Yvette (France); Neuville, D. [Physique des Mineraux et des Magmas, UMR-CNRS 7047, Institut de Physique du Globe, place Jussieu, 75252 Paris (France)

    2010-01-01

    High molybdenum concentration in glass compositions may lead to alkali and alkaline-earth molybdates crystallization during melt cooling that must be controlled particularly during the preparation of highly radioactive nuclear glassy waste forms. To understand the effect of molybdenum addition on the structure of a simplified nuclear glass and to know how composition changes can affect molybdates crystallization tendency, the structure of two glass series belonging to the SiO{sub 2}-B{sub 2}O{sub 3}-Na{sub 2}O-CaO-MoO{sub 3} system was studied by {sup 29}Si, {sup 11}B, {sup 23}Na MAS NMR and Raman spectroscopies by increasing MoO{sub 3} or B{sub 2}O{sub 3} concentrations. Increasing MoO{sub 3} amount induced an increase of the silicate network reticulation but no significant effect was observed on the proportion of BO{sub 4}{sup -} units and on the distribution of Na{sup +} cations in glass structure. By increasing B{sub 2}O{sub 3} concentration, a strong evolution of the distribution of Na{sup +} cations was observed that could explain the evolution of the nature of molybdate crystals (CaMoO{sub 4} or Na{sub 2}MoO{sub 4}) formed during melt cooling.

  19. Um ano de muitas preocupações, mas também de esperanças

    Directory of Open Access Journals (Sweden)

    Gabriela Litre

    2015-12-01

    Full Text Available O ano de 2015 foi farto em notícias ruins, mas se encerra com perspectivas boas. As más notícias confirmam que o mundo parece estar de cabeça para baixo, ao menos em matéria ambiental e de segurança internacional. Pioraram as condições climáticas globais; fanáticos religiosos lançaram ataques terroristas de grandes proporções, como os do dia 13 de novembro em Paris, além da surpreendente constituição de uma base territorial onde reina o terror, no Oriente Médio; uma persistente situação da pobreza extrema e de fome em grande escala em alguns países contrasta com a prosperidade em algumas nações; desastres ambientais e instabilidades políticas regionais e nacionais acontecem em cada continente. No Brasil, o rompimento de uma represa de lama e resíduos tóxicos de uma mineradora, em Mariana, Minas Gerais, provocou o que possivelmente seja a pior catástrofe ambiental já registrada no País.

  20. Preču uzskaites sistēmas izstrāde Django ietvarā

    OpenAIRE

    Kokorevičs, Miķelis

    2014-01-01

    Django ietvars ir moderns un pilnvērtīgs tīmekļa ietvars, kas ir veidots Python programmēšanas valodā. Šajā darbā, tiek pētīta Django ietvara funkcionalitāte un piemērotība individuālu preču uzskaites sistēmu izstrādē. Galvenie darba uzdevumi ir izpētīt Django ietvara iespējas un apkopot preču uzskaites sistēmas izstrādei nozīmīgākās priekšrocības. Šī darba rezultātā, tika aprakstīta Django ietvara funkcionalitāte, iespējas un uzbūve. Tika veikts salīdzinājums starp populārākajiem Pyth...

  1. Climate change adaptation in Tanjung Mas – Semarang: a comparison between male- and female-headed households

    Science.gov (United States)

    Handayani, W.; Ananda, M. R.; Esariti, L.; Anggraeni, M.

    2018-03-01

    Mainly due to its complexity, the effort to mainstream gender in addressing climate change issues has been far from the satisfying result. However, there is an urgent call to accommodate gender lens issues and to become more gender sensitive in an attempt to have an effective intervention in responding climate change impact. To enrich the reports on gender and climate change adaptation in city-based case, this paper aims to elaborate climate change adaptation in Tanjung Mas – Semarang city focusing on the gender perspective analysis in male- and female-headed households. The quantitative descriptive method is applied to carry out the analyses, including adaptive strategy and gender role analyses. The research result indicates there are not any significant differences in the climate change adaptation strategies applied in male- and female-headed households. This shows that women in the female-headed households, with their double burden, performed well in managing their roles. Therefore, in particular perspective, it may not be relevant to state that woman and female-headed households are likely to be more vulnerable compared with their counterparts.

  2. Written Exercises: Ancestral Magic and Emergent Intellectuals in Mia Couto, Lhoussain Azergui and Dorota Masłowska

    Directory of Open Access Journals (Sweden)

    Ewa Łukaszyk

    2016-12-01

    Full Text Available Written Exercises: Ancestral Magic and Emergent Intellectuals in Mia Couto, Lhoussain Azergui and Dorota Masłowska The article consists in a comparative reading of three novels: Um rio chamado tempo by Mia Couto, Le pain des corbeaux by Lhoussain Azergui and Paw królowej by Dorota Masłowska. In spite of the difference of the historical circumstances of Mozambique, Morocco and Poland, these three books meet at an intersecting point: the emergence of an intelligentsia that uses literacy and writing as an instrument to deconstruct the post-colonial concept of nation and to operate a trans-colonial renegotiation of identity. By the notion of trans-colonial, I understand the opposition against new kinds of symbolic violence that emerged after the end of the colonial period; here this new form of oppression is related to the concept of national unity – an artificial construct that leaves no place for a dualism or pluralism of cultural reality (two shores of the Zambezi river, Arab and Berber dualism in Morocco, “small homelands” in Poland. The young heroes of the novels grasp the pen in order to break through the falseness or the taboos created by the fathers, establishing, at the same time, the relation of solidarity with the world of the grandfathers. The act of writing becomes an actualization of the ancestral universe of magic. The settlement of accounts with the parental generation concerns the vision of nation built upon the resistance against the colonizer (it also refers to the Polish cultural formation, based on the tradition of uprisings and resistance against the Russians.   Ćwiczenia pisemne: magia przodków i nowi intelektualiści w powieściach Mii Couto, Lhoussaina Azerguiego i Doroty Masłowskiej Na podstawie powieści Um rio chamado tempo, uma casa chamada terra Mii Couto (2002, Le pain des corbeaux Lhoussaina Azerguiego (2012 oraz Paw królowej Doroty Masłowskiej (2005 dokonano analizy zjawiska wyłonienia się nowej

  3. Structure of Selected Derivates of p-Hydroxy Cynamonic Acid According to 13C CP MAS NMR and DFT Calculation

    International Nuclear Information System (INIS)

    Pisklak, D.M.; Wawer, I.; Tkaczyk, M.

    2005-01-01

    Derivatives of p-hydroxy cynamonic acid are widely occurring in fruits, vegetables, tea and coffee. They exhibit strong antioxidant activity due to the presence of phenolic group. Epidemiological, biological and biochemical data support health beneficial role of this group of compounds and anticarcinogenic, antimutagenic and antiinflamatory effects have been reported. The most common caffeic acid contributes significantly to the total polyphenol intake and has been suggested to play a role in the apparent association between the regular consumption of polyphenol-rich food and beverages, and the prevetion of inflammatory and proliferative diseases. 13 C MAS NMR spectra were recorded on a BRUKER DSX 400 spectrometer at 400,13. Powder samples were spun in a 4 mm rotor at 10 kHz ( 13 C). Signals were assigned:- By comparison with solution spectra; - Using dipolar dephasing and variable contact time experiments; - Confirmed by DFT calculations of shielding constants. The differences in chemical shifts between solution and solid state spectra are due to the formation of intramolecular and intermolecular hydrogen bonds, including C-OH...OC within cyclic dimers. (author)

  4. Quality of spelt pasta enriched with eggs and identification of eggs using 13C MAS NMR spectroscopy

    Directory of Open Access Journals (Sweden)

    Filipović Jelena S.

    2015-01-01

    Full Text Available This paper deals with the characteristics of spelt pasta enriched with eggs. Eggs were added to spelt farina in the quantity of 0, 124 or 248 g/kg (equivalent to 0, 3 or 6 eggs, respectively. Post-hoc Tukey’s HSD test at 95% confidence limit showed significant differences between various samples. Relatively low coefficients of variation have been obtained for each applied assay (1.25-12.42%, which confirmed the high accuracy measurements and statistically significant results. Standard score analysis is applied for accessing the contribution of eggs content to spelt pasta quality. Maximum scores regarding quality (0.89 and chemical characteristics (0.70, have been obtained for 6 eggs spelt pasta formulation. It is also shown that the presence of eggs in pasta can be clearly confirmed by 13C MAS NMR spectroscopy. Simultaneous increase in area of peak positioned at 29.5 and 176 ppm is directly associated with the increase in the content of added eggs in the corresponding samples. Pertinent data point at positive contribution of eggs to the spelt pasta and also that NMR spectrum can be used in the egg quantity control. [Projekat Ministarstva nauke Republike Srbije, br. TRI 46005 i br. TR 31029

  5. Protective effects of vitamin E and Cornus mas fruit extract on methotrexate-induced cytotoxicity in sperms of adult mice

    Directory of Open Access Journals (Sweden)

    Leila Zarei

    2014-03-01

    Full Text Available This study was aimed to assess the protective effects of Cornus mas fruit extract (CMFE and vitamin E (Vit E on sperm quality parameters in the methotrexate (MTX-treated mice. Forty-eight young adult male mice (8-12 weeks were randomly divided into six groups including control and test groups. The control group received normal saline orally , and the test groups were treated MTX (20 mg kg-1, ip, once weekly, MTX + CMFE (250 mg kg-1, MTX + CMFE (500 mg kg-1, MTX + CMFE (1000 mg kg-1, and MTX + Vit E (100 IU kg-1, po for 35 consecutive days. On day 35, after euthanasia the epididymal sperms were isolated. Then the total mean sperm count, sperm viability and motility were determined. The total antioxidant capacity (TAOC of all experimental groups were also evaluated. The MTX-treated animals showed a significant changes in all parameters of sperm quality assessment compared to the control group. Both Vit E and CMFE were able to protect from MTX-induced effects on sperm maturity and DNA damage. Co-administration of MTX and CMFE and/or Vit E resulted in protection from MTX-reduced TAOC. In conclusion, these data suggested that MTX administration could adversely affect the sperm quality. Moreover, the protective effect of Vit E and CMFE on MTX-induced sperm toxicity was also documented.

  6. Lightweight hydrogen-storage material Mg0.65Sc0.35D2 studied with 2H and 2H–{45Sc} MAS NMR exchange spectroscopy

    NARCIS (Netherlands)

    Srinivasan, S.; Magusin, P.C.M.M.

    2011-01-01

    Using double-quantum 2H MAS NMR with 45Sc recoupling and Bloch–Siegert compensated 2H–{45Sc} TRAPDOR we have identified the overlapping NMR signals of deuterium with and without scandium neighbors in Mg0.65Sc0.35D2, a candidate lightweight material for hydrogen storage. At room temperature we also

  7. Protein resonance assignment at MAS frequencies approaching 100 kHz: a quantitative comparison of J-coupling and dipolar-coupling-based transfer methods

    Energy Technology Data Exchange (ETDEWEB)

    Penzel, Susanne; Smith, Albert A.; Agarwal, Vipin; Hunkeler, Andreas [ETH Zürich, Physical Chemistry (Switzerland); Org, Mai-Liis; Samoson, Ago, E-mail: ago.samoson@ttu.ee [Tallinn University of Technology, NMR Instituut, Tartu Teadus, Tehnomeedikum (Estonia); Böckmann, Anja, E-mail: a.bockmann@ibcp.fr [UMR 5086 CNRS/Université de Lyon 1, Institut de Biologie et Chimie des Protéines (France); Ernst, Matthias, E-mail: maer@ethz.ch; Meier, Beat H., E-mail: beme@ethz.ch [ETH Zürich, Physical Chemistry (Switzerland)

    2015-10-15

    We discuss the optimum experimental conditions to obtain assignment spectra for solid proteins at magic-angle spinning (MAS) frequencies around 100 kHz. We present a systematic examination of the MAS dependence of the amide proton T{sub 2}′ times and a site-specific comparison of T{sub 2}′ at 93 kHz versus 60 kHz MAS frequency. A quantitative analysis of transfer efficiencies of building blocks, as they are used for typical 3D experiments, was performed. To do this, we compared dipolar-coupling and J-coupling based transfer steps. The building blocks were then combined into 3D experiments for sequential resonance assignment, where we evaluated signal-to-noise ratio and information content of the different 3D spectra in order to identify the best assignment strategy. Based on this comparison, six experiments were selected to optimally assign the model protein ubiquitin, solely using spectra acquired at 93 kHz MAS. Within 3 days of instrument time, the required spectra were recorded from which the backbone resonances have been assigned to over 96 %.

  8. Personālā datora sistēmas bloka vides snieguma novērtējums un ekodizaina analīze

    OpenAIRE

    Šteina, Māra

    2009-01-01

    Maģistra darba „Personālā datora sistēmas bloka vides snieguma novērtējums un ekodizaina analīze” pamatā ir biroja datora sistēmas bloka ietekmes uz vidi novērtējums visā tā dzīves cikla laikā, izvērtējot arī lietotāju un iesaistīto pušu nozīmi. Darbs sastāv no divām daļām – teorētiskās un praktiskās. Pirmā daļa ir teorētiskajā daļa, kurā autore apskatīja pieejamos literatūras avotus un citu autoru darbus, izvērtējot tēmas aktualitāti, galvenās problēmas un to risinājumus. Otrā daļa ...

  9. KrasMAS: Implementation of a nuclear material computerized accounting system at the Mining and Chemical Combine through the Russian/US cooperative MPC and A program

    International Nuclear Information System (INIS)

    Dorofeev, K.V.; Zhidkov, V.V.; Martinez, B.J.; Perry, R.T.; Scott, S.C.

    1998-01-01

    The Russian/US Mining and Chemical Combine (Gorno-Kimichesky Kombinat, GKhK, also referred to as Krasnoyarsk-26) Material Protection, Control and Accounting (MPC and A) project was initiated in June 1996. A critical component of the ongoing cooperative MPC and A enhancements at the GKhK is the implementation of a computerized nuclear material control and accountability (MC and A) system. This system must meet the MC and A requirements of the GKhK by integrating the information generated by numerous existing and new MC and A components in place at the GKhK (e.g., scales, bar-code equipment, NDA measurement systems). During the first phase of this effort, the GKhK adapted CoreMAS (developed at Los Alamos National Laboratory) for use in the PuO 2 storage facility. This included formulation of Web-based user interfaces for plant personnel, Russification of the existing user interface, and at the functional level, modification of the CoreMAS stored procedures. The modified system is referred to as KrasMAS and builds upon completed work on CoreMAS. Ongoing efforts include adding GKhK specific report forms and expanding the functionality of the system for implementation at the radiochemical processing and reactor plants of the GKhK. Collaborations with other Russian facilities for appropriate parts of these efforts will be pursued

  10. A MAS NMR and DRIFT study of the Ga species in Ga/H-ZSM5 catalysts and their effect on propane ammoxidation

    NARCIS (Netherlands)

    Pal, P.; Quartararo, J.; Hamid, abd S.B.; Derouane, E.G.; Védrine, J.C.; Magusin, P.C.M.M.; Anderson, B.G.

    2005-01-01

    71Ga, 27Al and 29Si MAS-NMR and DRIFT spectroscopies were used to characterize the state of gallium in Ga/H-ZSM5 catalysts tested for their ability to catalyse the ammoxidation of propane. Ga-species were observed in two different possible environments: octahedrally-coordinated gallium in small

  11. Characteristics and Sampling Efficiencies of Two Impactor Bioaerosol Samplers: MAS-100(Registered) (Microbial Air Monitoring System) and Single-Stage Andersen Viable Microbial Samplers

    National Research Council Canada - National Science Library

    Hottell, K

    2004-01-01

    .... A petri dish with agar is used as the impaction surface for these samplers. The MAS-l00 is a single-stage impactor that aspirates air through a 400-hole perforated entry plate onto an agar plate at an airflow rate of 100 L/min...

  12. Hydration kinetics for the alite, belite, and calcium aluminate phase in Portland cements from 27Al and 29Si MAS NMR spectroscopy

    DEFF Research Database (Denmark)

    Skibsted, Jørgen; Jensen, Ole Mejlhede; Jakobsen, Hans Jørgen

    1997-01-01

    29Si magic-angle spinning (MAS) NMR spectroscopy is shown to be a valuable tool for obtaining the quantities of alite and belite in hydrated Portland cements. The hydration (1-180 days) of a white Portland cement with 10 wt.% silica fume added is investigated and the degrees of hydration for alite...

  13. Banku reklāmas stratēģiju un valsts ekonomiskā stāvokļa mijiedarbība

    OpenAIRE

    Vernere, Elīna

    2009-01-01

    Darba tēma ir banku reklāmas stratēģiju un valsts ekonomiskā stāvokļa mijiedarbība. Galvenais pētījuma mērķis bija izprast, kā pašreizējā valsts ekonomiskā situācija izmainījusi sabiedrības vajadzības, pieprasījumu pēc banku pakalpojumiem un līdz ar to arī banku komunikāciju ar saviem klientiem ar vides reklāmas ziņojumu palīdzību. Galvenais pētījuma uzsvars tika likts uz reklāmas ziņojumu emocionālajiem un racionālajiem aspektiem. Papildus veiktajam pētījumam tika apskatīta arī reklāmas teor...

  14. The cave paintings of the Covatina del Tossalet del Mas de la Rambla», Vilafranca, Castellón | Las pinturas rupestres de la "Covatina del Tossalet del Mas de la Rambla", Villafranca, Castellón | Las pinturas rupestres de la "Covatina del Tossalet del Mas de la Rambla", Villafranca, Castellón

    Directory of Open Access Journals (Sweden)

    Norberto Mesado Olivier

    1989-12-01

    Full Text Available Vilafranca, en el linde N del País, conserva en «La Covatina del Tossalet del Mas de la Rambla», un grupo de unas 24 figuras pertenecientes al tradicionalmennte denominado «Arte Levantino», y que recientemente hemos convenido en llamar «Arte Rupestre del Neolítico Inciso». Destaca por novedosa la caza de una gran ave rapaz (posiblemente un córvido, herida por un proyectil procedente de una honda, arma que lleva un bello cazador en «vuelo», el cual viste sofisticadamente. Otro grupo de figuras humanas singulares aparecen capturando víboras, práctica que llegó tanto en Vilafranca como en el vecino pueblo de Castellfort, a los inicios del siglo XX. Tan singular depredación habrá de relacionarse con la extracción del mortífero veneno de la «vípera Latasti». Su empleo tanto pudo servir para empozoñar las puntas de las saetas de los cazadores prehistóricos de este importantísimo foco del Maestrazgo, o como «fármacos» al estilo de la «Triaca Magna». | Vilafranca, dans la limite Nord du Pays, a dans «La Covatina del Tossalet del Mas de la Rambla», un groupe d'unes 24 figures appartenant au traditionnelment dénomme «Arte Levantino» et que récemment on a accordé dénomé «Art Rupestre du Néolithique Haché». Détache, par nouvelle, la chasse d'un gran oiseau de proie (possiblement un Corvidé, bléssé par un projectile originaire d'une fronde d'un chasseur, lequel est habillé sophistiquément. Un autre groupe de figures humaines se trouve chassant des vipéres, usage qui est arrivé á Vilafranca jusqu'au XXéme siécle. Cette singuliére chasse doit étre lié a l'extraction du poison meutrier de la «Vipera Latasti». Sa finalité aurait bien pu étre empoisonner les pointes dis fleches utilisées par les chasseurs préhistoriques de cette tres importante aire du «Maestrazgo»; ou bien comme «medicament» du méme type que la »Triarca Magna».

  15. Pre- And Post-Enron Learnings On Learning In M&A Environments - A Qualitative Study In Preparation Of A Dissertation On The Influence Of Management Andragogy On Executives Ability To Successfully Manage M&As

    OpenAIRE

    Jacqueline Fendt

    2011-01-01

    In a global economy characterized by convergence and consolidation, by shareholder pressure, by the war for talent, for knowledge and for customer bondage, Merger and Acquisition transactions (M&As) are seen as a fast, efficient and spectacular way to innovate. M&As are therefore a frequently used strategic tool for corporate development. However, as of now, more than 75% of all M&As fail to meet objectives and 50% even destroy shareholder value. M&As often fail due to poor leadership. Th...

  16. High-resolution magnetic resonance imaging (HR-MRI) of the pleura and chest wall: Normal findings and pathological changes

    International Nuclear Information System (INIS)

    Bittner, R.C.; Schnoy, N.; Schoenfeld, N.; Grassot, A.; Loddenkemper, R.; Lode, H.; Kaiser, D.; Krumhaar, D.; Felix, R.

    1995-01-01

    To determine the value of high-resolution MRI in pleural and chest wall diseases, the normal and pathologic costal pleura and adjacent chest wall between paravertebral and the axillar region were examined with contrast enhanced high-resolution T 1 -weighted MRI images using a surface coil. Normal anatomy was evaluated in 5 healthy volunteers and a normal specimen of the thoracic wall, and correlation was made with corresponding HR-CT and histologic sections. CT-proved focal and diffuse changes of the pleura and the chest wall in 36 patients underwent HR-MRI, and visual comparison of MRI and CT was done retrospectively. Especially sagittal T 1 -weighted HR-MRI images allowed accurate delineation of the peripleural fat layer (PFL) and the innermost intercostal muscle (IIM), which served as landmarks of the intact inner chest wall. PFL and IIM were well delineated in 3/4 patients with tuberculous pleuritis, and in all 7 patients with non-specific pleuritis, as opposed to impairment of the PFL and/or the IIM, which was detected in 15/18 malignancies as a pattern of malignant chest wall involvement. In one case of tuberculous pleural empyema with edema of the inner chest wall HR-MRI produced false positive diagnosis of malignant disease. HR-MRI images improved non-invasive evaluation of pleural and chest wall diseases, and allowed for differentiation of bengin and malignant changes. (orig./MG) [de

  17. Recombinant protein of heptad-repeat HR212, a stable fusion inhibitor with potent anti-HIV action in vitro

    International Nuclear Information System (INIS)

    Pang, Wei; Wang Ruirui; Yang Liumeng; Liu Changmei; Tien Po; Zheng Yongtang

    2008-01-01

    HR212, a recombinant protein expressed in Escherichia coli, has been previously reported to inhibit HIV-1 membrane fusion at low nanomolar level. Here we report that HR212 is effective in blocking laboratory strain HIV-1 IIIB entry and replication with EC 50 values of 3.92 ± 0.62 and 6.59 ± 1.74 nM, respectively, and inhibiting infection by clinic isolate HIV-1 KM018 with EC 50 values of 44.44 ± 10.20 nM, as well as suppressing HIV-1-induced cytopathic effect with an EC 50 value of 3.04 ± 1.20 nM. It also inhibited HIV-2 ROD and HIV-2 CBL-20 entry and replication in the μM range. Notably, HR212 was highly effective against T20-resistant strains with EC 50 values ranging from 5.09 to 7.75 nM. Unlike T20, HR212 showed stability sufficient to inhibit syncytia formation in a time-of-addition assay, and was insensitive to proteinase K digestion. These results suggest that HR212 has great potential to be further developed as novel HIV-1 fusion inhibitor for treatment of HIV/AIDS patients, particularly for those infected by T20-resistant variants

  18. Reducing employees’ turnover intention through Hr-induced organizational citizenship behaviour: Leader-member exchange as the mediator

    Directory of Open Access Journals (Sweden)

    YU GHEE WEE

    2013-07-01

    Full Text Available This study examines the possibility of inducing organizational citizenship behavior (OCB through human resource (HR philosophy and high involvement HR practices administered at the workplace. Leader-member exchange (LMX, a basis of relational infrastructure, is posited to be a potential mediator. Data was collected from hotel frontline employees, tested and analyzed through structural equation modeling. Findings show that HR philosophy drives the formulation of the bundles of high involvement human resource practices and such philosophy contribute to employees’ willingness in exhibiting organizational citizenship behavior (OCB directed at individuals (OCBI as well as organizations (OCBO as a whole. High involvement HR practices, however, do not elicit OCB but these practices are significantly related to LMX, a new theoretical insight which should invite future research. Although exchanges between supervisors and subordinates are shown to have influences on employees’ willingness in performing OCB, LMX does not, however, mediate the relationship between high involvement HR practices and OCB. Overall, hotel frontline employees participated in this study exhibit more OCBO, rather than OCBI; and such behavior reduce their intention to leave. Both theoretical and practical implications as well as avenues for future research are discussed.

  19. [THE FIRST EPIDEMIOLOGICAL DATA ABOUT THE HR-HUMAN PAPILLOMA VIRUS TYPES IN SOUTH AND NORTHERN BULGARIA].

    Science.gov (United States)

    Kovachev, S; Slavov, V; Slavova, K; Ganovska, A

    2015-01-01

    The aim of our study were to evaluate the prevalence of HR-HPV infection in women between 15 and 55 years of age in the South and Northern Bulgaria. We have analyzed the HPV status (using DNA-sorb-AM nucleic acid extraction kit) in cervical samples collected during a 3 year period (2010-2012) from 1020 women, aged 15-55 and divided in four age groups, who attended their gynecologists for HPV-DNA cervical test. The rate of the HR-HPV infection was established to be 39.9%. HR-HPV negative were 60.1% of the evaluated subjects. The most commonly isolated genotype in all 407 (100%) infected women was HPV 16 - 190 women (46.7%), followed by HPV 56 - 78 (19.1%), HPV 31- 48 (11.8%) and HPV 33 - 45 (11.1%). To our knowledge, this is the first survey evaluating the prevalence of HR-HPV infection in the South and Northern regions of Bulgarian towns and drawing attention to the unusually high proportion of different HR-HPV.

  20. E2F1 interactions with hHR23A inhibit its degradation and promote DNA repair.

    Science.gov (United States)

    Singh, Randeep K; Dagnino, Lina

    2016-05-03

    Nucleotide excision repair (NER) is a major mechanism for removal of DNA lesions induced by exposure to UV radiation in the epidermis. Recognition of damaged DNA sites is the initial step in their repair, and requires multiprotein complexes that contain XPC and hHR23 proteins, or their orthologues. A variety of transcription factors are also involved in NER, including E2F1. In epidermal keratinocytes, UV exposure induces E2F1 phosphorylation, which allows it to recruit various NER factors to sites of DNA damage. However, the relationship between E2F1 and hHR23 proteins vis-à-vis NER has remained unexplored. We now show that E2F1 and hHR23 proteins can interact, and this interaction stabilizes E2F1, inhibiting its proteasomal degradation. Reciprocally, E2F1 regulates hHR23A subcellular localization, recruiting it to sites of DNA photodamage. As a result, E2F1 and hHR23A enhance DNA repair following exposure to UV radiation, contributing to genomic stability in the epidermis.

  1. RESHAPING ORGANIZATIONS – MANAGING PEOPLE THROUGH HR STRATEGIES AND INTERNAL MARKETING

    Directory of Open Access Journals (Sweden)

    Roxana Cioclov

    2014-10-01

    Full Text Available The following paper aims at presenting key concepts in regard to the interconnectivity between two similar and frequently confused practices – Human Resource Management and Internal Marketing. Therefore, it is intend to present both fields distinctively, in order to emphasise in the end the added value of the two working together. Given the fact that, in the specialised literature, there are different approaches on this subject and many questions raised regarding the separation of the instruments and particular objectives of the two practices, the paper presents a simplified approach on the HRM Cycle in comparison with the IM Cycle. Therefore, the paper is structured as follows: (1 HRM’s impact on the general activity of an organization – whether it is a manufacturing company or a service provider; (2 IM’s impact on the internal and external environment of the organization; (3 Analysis on the connection and in-/inter-/dependency of the two concepts and their meaning. Although HRM seems to bring numerous advantages to the organization, the current paper states that HR cannot be done at the same efficiency level in the absence of good Internal Marketing practices that allow the word - of - mouth to spread between the present and possible future employees. It is about a good branding that has to exceed the company’s geographical boundaries and to create the need, not only in terms of product consumer’s behavior, but also in regard to employees that want to be part of the brand.

  2. Mitigation action plan for the 100-KR-4, 100-HR-3 pump and treat

    International Nuclear Information System (INIS)

    Weiss, S.G.

    1996-10-01

    This project involves drilling 22 wells, improving access roads to existing new wells, laying connecting pipes, and constructing groundwater treatment facilities in the 100-KR-4 and 100-HR-3 Operable Units. These facilities are located at the Hanford Site in Richland, Washington. The drilling is expected to be completed by October 1996, but the treatment operations will continue for approximately 10 years. Thirteen of the new wells are to be placed in the 100-K Area, five in the 100-H Area, and four in the 100-D Area. A 4 km (2.5 mi) pipeline will run from the wells at the 100-D Area to the treatment facility at the 100-H Area. The 116-K-2 Trench received reactor effluents from 1955 to 1971. It is 1,460 m long by 16.4 m wide by 5.5 m deep with spoil pits at the surface on both sides. Washouts occurred during operation, causing several surface contamination areas between the trench and river that were covered with a few feet of soil

  3. Anthocyanins and antioxidant capacities of six Chilean berries by HPLC-HR-ESI-ToF-MS.

    Science.gov (United States)

    Ramirez, Javier E; Zambrano, Ricardo; Sepúlveda, Beatriz; Kennelly, Edward J; Simirgiotis, Mario J

    2015-06-01

    The HPLC profiles of six fruits endemic of the VIII region of Chile were investigated using high resolution mass analysis (HR-ToF-ESI-MS). The anthocyanin fingerprints generated for the fruits were compared and the antioxidant capacities measured by the scavenging of the DPPH radical, the ferric reducing antioxidant power (FRAP), the superoxide anion scavenging activity assay (SA), and correlated with the inhibition of lipid peroxidation in human erythrocytes (LP) and total content of phenolics, flavonoids and anthocyanins measured by spectroscopic methods. Several anthocyanins were identified, including 3-O-glycosides derivatives of delphinidin, cyanidin, petunidin, peonidin and malvidin. Three phenolic acids (feruloyl-quinic acid, chlorogenic acid, and neochlorogenic acid) and five flavonols (hyperoside, isoquercitrin, quercetin, rutin, myricetin and isorhamnetin) were also identified. Calafate fruits showed the highest antioxidant activity. However, the highest LP activity was found for Chilean blueberries (>95%) followed by calafate fruits (91.27%) and luma (83.4%). Copyright © 2014 Elsevier Ltd. All rights reserved.

  4. A ∼ 3.8 hr PERIODICITY FROM AN ULTRASOFT ACTIVE GALACTIC NUCLEUS CANDIDATE

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Dacheng; Irwin, Jimmy A. [Department of Physics and Astronomy, University of Alabama, Box 870324, Tuscaloosa, AL 35487 (United States); Godet, Olivier; Webb, Natalie A.; Barret, Didier, E-mail: dlin@ua.edu [CNRS, IRAP, 9 avenue du Colonel Roche, BP 44346, F-31028 Toulouse Cedex 4 (France)

    2013-10-10

    Very few galactic nuclei are found to show significant X-ray quasi-periodic oscillations (QPOs). After carefully modeling the noise continuum, we find that the ∼3.8 hr QPO in the ultrasoft active galactic nucleus candidate 2XMM J123103.2+110648 was significantly detected (∼5σ) in two XMM-Newton observations in 2005, but not in the one in 2003. The QPO root mean square (rms) is very high and increases from ∼25% in 0.2-0.5 keV to ∼50% in 1-2 keV. The QPO probably corresponds to the low-frequency type in Galactic black hole X-ray binaries, considering its large rms and the probably low mass (∼10{sup 5} M {sub ☉}) of the black hole in the nucleus. We also fit the soft X-ray spectra from the three XMM-Newton observations and find that they can be described with either pure thermal disk emission or optically thick low-temperature Comptonization. We see no clear X-ray emission from the two Swift observations in 2013, indicating lower source fluxes than those in XMM-Newton observations.

  5. Investigation of HV/HR-CMOS technology for the ATLAS Phase-II Strip Tracker Upgrade

    International Nuclear Information System (INIS)

    Fadeyev, V.; Galloway, Z.; Grabas, H.; Grillo, A.A.; Liang, Z.; Martinez-Mckinney, F.; Seiden, A.; Volk, J.; Affolder, A.; Buckland, M.; Meng, L.; Arndt, K.; Bortoletto, D.; Huffman, T.; John, J.; McMahon, S.; Nickerson, R.; Phillips, P.; Plackett, R.; Shipsey, I.

    2016-01-01

    ATLAS has formed strip CMOS project to study the use of CMOS MAPS devices as silicon strip sensors for the Phase-II Strip Tracker Upgrade. This choice of sensors promises several advantages over the conventional baseline design, such as better resolution, less material in the tracking volume, and faster construction speed. At the same time, many design features of the sensors are driven by the requirement of minimizing the impact on the rest of the detector. Hence the target devices feature long pixels which are grouped to form a virtual strip with binary-encoded z position. The key performance aspects are radiation hardness compatibility with HL-LHC environment, as well as extraction of the full hit position with full-reticle readout architecture. To date, several test chips have been submitted using two different CMOS technologies. The AMS 350 nm is a high voltage CMOS process (HV-CMOS), that features the sensor bias of up to 120 V. The TowerJazz 180 nm high resistivity CMOS process (HR-CMOS) uses a high resistivity epitaxial layer to provide the depletion region on top of the substrate. We have evaluated passive pixel performance, and charge collection projections. The results strongly support the radiation tolerance of these devices to radiation dose of the HL-LHC in the strip tracker region. We also describe design features for the next chip submission that are motivated by our technology evaluation.

  6. Investigation of HV/HR-CMOS technology for the ATLAS Phase-II Strip Tracker Upgrade

    Science.gov (United States)

    Fadeyev, V.; Galloway, Z.; Grabas, H.; Grillo, A. A.; Liang, Z.; Martinez-Mckinney, F.; Seiden, A.; Volk, J.; Affolder, A.; Buckland, M.; Meng, L.; Arndt, K.; Bortoletto, D.; Huffman, T.; John, J.; McMahon, S.; Nickerson, R.; Phillips, P.; Plackett, R.; Shipsey, I.; Vigani, L.; Bates, R.; Blue, A.; Buttar, C.; Kanisauskas, K.; Maneuski, D.; Benoit, M.; Di Bello, F.; Caragiulo, P.; Dragone, A.; Grenier, P.; Kenney, C.; Rubbo, F.; Segal, J.; Su, D.; Tamma, C.; Das, D.; Dopke, J.; Turchetta, R.; Wilson, F.; Worm, S.; Ehrler, F.; Peric, I.; Gregor, I. M.; Stanitzki, M.; Hoeferkamp, M.; Seidel, S.; Hommels, L. B. A.; Kramberger, G.; Mandić, I.; Mikuž, M.; Muenstermann, D.; Wang, R.; Zhang, J.; Warren, M.; Song, W.; Xiu, Q.; Zhu, H.

    2016-09-01

    ATLAS has formed strip CMOS project to study the use of CMOS MAPS devices as silicon strip sensors for the Phase-II Strip Tracker Upgrade. This choice of sensors promises several advantages over the conventional baseline design, such as better resolution, less material in the tracking volume, and faster construction speed. At the same time, many design features of the sensors are driven by the requirement of minimizing the impact on the rest of the detector. Hence the target devices feature long pixels which are grouped to form a virtual strip with binary-encoded z position. The key performance aspects are radiation hardness compatibility with HL-LHC environment, as well as extraction of the full hit position with full-reticle readout architecture. To date, several test chips have been submitted using two different CMOS technologies. The AMS 350 nm is a high voltage CMOS process (HV-CMOS), that features the sensor bias of up to 120 V. The TowerJazz 180 nm high resistivity CMOS process (HR-CMOS) uses a high resistivity epitaxial layer to provide the depletion region on top of the substrate. We have evaluated passive pixel performance, and charge collection projections. The results strongly support the radiation tolerance of these devices to radiation dose of the HL-LHC in the strip tracker region. We also describe design features for the next chip submission that are motivated by our technology evaluation.

  7. Analysis of performance measurement at HR-GR Department using the balance scorecard method

    Science.gov (United States)

    Vienni; Bachtiar, M.

    2017-12-01

    PT. X is a company engaged in logistics service in Indonesia. Every company will certainly face a dynamic business environment. Competitors not only from domestic but also from overseas. To be successful in achieving its objectives, company should have a comprehensive measurement system as a strategy feedback that will drive the performance of company. HR-GA department is department that coordinate directly with company’s management. Company through departments expect development goals in individual and also support of infrastructure will run smoothly. In 2015, company has taken steps to conduct a balanced scorecard as performance measurement. Nevertheless, a number of factors so it cannot run optimally. This study aims to analyse the current system and provided suggestions in order to give an overview to department related to its current performance. The results of data processing show that there are 8 objective strategies that have been formulated with 9 key performance indicators. Based on the results of scorecard, obtained values of 4.44 for customer perspective, 4.32 for internal business process perspective & 5.00 for learning and growth perspective. It concludes that performance based on perspectives are categorized very well

  8. PDK1 and HR46 gene homologs tie social behavior to ovary signals.

    Directory of Open Access Journals (Sweden)

    Ying Wang

    Full Text Available The genetic basis of division of labor in social insects is a central question in evolutionary and behavioral biology. The honey bee is a model for studying evolutionary behavioral genetics because of its well characterized age-correlated division of labor. After an initial period of within-nest tasks, 2-3 week-old worker bees begin foraging outside the nest. Individuals often specialize by biasing their foraging efforts toward collecting pollen or nectar. Efforts to explain the origins of foraging specialization suggest that division of labor between nectar and pollen foraging specialists is influenced by genes with effects on reproductive physiology. Quantitative trait loci (QTL mapping of foraging behavior also reveals candidate genes for reproductive traits. Here, we address the linkage of reproductive anatomy to behavior, using backcross QTL analysis, behavioral and anatomical phenotyping, candidate gene expression studies, and backcross confirmation of gene-to-anatomical trait associations. Our data show for the first time that the activity of two positional candidate genes for behavior, PDK1 and HR46, have direct genetic relationships to ovary size, a central reproductive trait that correlates with the nectar and pollen foraging bias of workers. These findings implicate two genes that were not known previously to influence complex social behavior. Also, they outline how selection may have acted on gene networks that affect reproductive resource allocation and behavior to facilitate the evolution of social foraging in honey bees.

  9. Information from the HR Department for members of the personnel residing in FRANCE

    CERN Document Server

    HR Department

    2007-01-01

    Tax assessment notice sent by the French Tax Centre Members of the personnel residing in France have received (or are about to receive) a document issued by their local Centre des Impôts (CDI) entitled «Avis d’impôt – IMPÔT SUR LES REVENUS DE 2006». The document states in particular that: «La déclaration que vous avez déposée ne comporte aucun revenu pour l’année 2006. Je vous informe que le présent avis ne constitue pas un justificatif d’absence de tout revenu. Vous avez perçu des revenus en provenance d’organismes internationaux, de missions diplomatiques ou consulaires exonérés d’impôt en France. Indiquez-les au bas de cet avis» [1] This document must not be returned to your CDI. However, you must keep it as the French authorities may ask you to produce it as evidence of your tax position in France. Further information may be obtained directly from your CDI. HR DepartmentTel: 73903 [1] CERN translation, for information only: "The declaration...

  10. Investigation of HV/HR-CMOS technology for the ATLAS Phase-II Strip Tracker Upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Fadeyev, V., E-mail: fadeyev@ucsc.edu [Santa Cruz Institute for Particle Physics, University of California, Santa Cruz, CA 95064 (United States); Galloway, Z.; Grabas, H.; Grillo, A.A.; Liang, Z.; Martinez-Mckinney, F.; Seiden, A.; Volk, J. [Santa Cruz Institute for Particle Physics, University of California, Santa Cruz, CA 95064 (United States); Affolder, A.; Buckland, M.; Meng, L. [Department of Physics, University of Liverpool, O. Lodge Laboratory, Oxford Street, Liverpool L69 7ZE (United Kingdom); Arndt, K.; Bortoletto, D.; Huffman, T.; John, J.; McMahon, S.; Nickerson, R.; Phillips, P.; Plackett, R.; Shipsey, I. [Department of Physics, Oxford University, Oxford (United Kingdom); and others

    2016-09-21

    ATLAS has formed strip CMOS project to study the use of CMOS MAPS devices as silicon strip sensors for the Phase-II Strip Tracker Upgrade. This choice of sensors promises several advantages over the conventional baseline design, such as better resolution, less material in the tracking volume, and faster construction speed. At the same time, many design features of the sensors are driven by the requirement of minimizing the impact on the rest of the detector. Hence the target devices feature long pixels which are grouped to form a virtual strip with binary-encoded z position. The key performance aspects are radiation hardness compatibility with HL-LHC environment, as well as extraction of the full hit position with full-reticle readout architecture. To date, several test chips have been submitted using two different CMOS technologies. The AMS 350 nm is a high voltage CMOS process (HV-CMOS), that features the sensor bias of up to 120 V. The TowerJazz 180 nm high resistivity CMOS process (HR-CMOS) uses a high resistivity epitaxial layer to provide the depletion region on top of the substrate. We have evaluated passive pixel performance, and charge collection projections. The results strongly support the radiation tolerance of these devices to radiation dose of the HL-LHC in the strip tracker region. We also describe design features for the next chip submission that are motivated by our technology evaluation.

  11. PLEIADES-HR SYSTEM PRODUCTS PERFORMANCE AFTER IN-ORBIT COMMISSIONING PHASE

    Directory of Open Access Journals (Sweden)

    C. Panem

    2012-07-01

    Full Text Available Launched on 2011, December 16th by the second Soyuz operated in French Guiana, PLEIADES-HR acquired its first high resolution images 3 days after. The PLEIADES program is a space Earth Observation system led by the French Space Agency (CNES, it provides the first european high resolution satellite which will simultaneously acquire in Panchromatic and Multi- Spectral modes 20 km wide images with a 70 cm nadir resolution. Imaging capabilities have been highly optimized in order to acquire, in the same pass, along-track mosaics, stereo pairs and triplets, and multi-targets. Ground segment processes automatically data to ensure operational requirements and quick access to images for the users. Since ground processing capabilities have been taken into account very early in the mission development, it has been possible to relax some costly on-board components requirements, in order to achieve a cost effective on-board/ground compromise. Starting from the PLEIADES system and on board characteristics, this paper first presents an overview of ground segment functional breakdown. Then it focuses more precisely on the different levels of products and associated processing performances. Finally the paper shows how appropriate ground processing systems allowed CNES Image Quality team to assess radiometric and geometric performances during the 6 first months of PLEIADES 1A.

  12. Abundance analysis from the UV spectrum of the He-w star HR 6000

    International Nuclear Information System (INIS)

    Castelli, F.; Cornachin, M.; Morossi, C.; Hack, M.

    1984-01-01

    A high resolution spectrum of the He-w star HR 6000, covering the SW and LW regions, has been analysed. A fully line-blanketed model atmosphere with parameters Tsub(e) = 14000 K, log g = 4, microturbulence xi = 2 km.s -1 has been adopted. This model is in agreement with the photometric data and yields the same abundance for the Fe II and Fe III ions. By using the synthetic spectrum method we compared the observed lines with the computed ones. We find an underabundance of C, Al Si, Mg, S, Sc, Co, Ni, Zn and an overabundance of Be, P, Cl, Ti, Mn, Fe, Ga. B, O, Cr have nearly solar abundances. Circumstellar (or interstellar) shortward-shifted components affect the strong resonance lines of the following ions: C II(1) lambda 1334.535, O I(2) lambda 1302.074,Mg II(1) lambda 2795.523, lambda 2802.698, Si II(3) lambda 1304.369, Fe II(1) lambda 2599.395

  13. 100-HR-1 Operable Unit focused feasibility study report. Draft A

    International Nuclear Information System (INIS)

    1994-09-01

    The standard Comprehensive Environmental Response, Compensation, and Liability Act of 1980 Feasibility Study (FS) includes development and screening of alternatives (phases 1 and 2) and the detailed analysis of alternatives (phase 3). This focused feasibility study (FFS) constitutes the phase 3 portion of the FS process. The FFS process is conducted in two stages, a Process Document (DOE-RL 1994a) and an operable unit-specific FFS document, such as this one. The FFS process is performed by implementing a ''plug-in'' style approach as defined in great detail in the Process Document. The objective of this operable unit-specific FFS is to provide decision makers with sufficient information to allow appropriate and timely selection of interim remedial measures (IRM) for sites associated with the 100-HR-1 Operable Unit. The IRM candidate waste sites are determined in the limited field investigation. Site profiles are developed for each of these waste sites. The site profiles are used in the application of the plug-in approach. The waste site either plugs into the analysis of the alternatives for the group, or deviations from the developed group alternatives are described and documented

  14. From SPOT 5 to Pleiades HR: evolution of the instrumental specifications

    Science.gov (United States)

    Rosak, A.; Latry, C.; Pascal, V.; Laubier, D.

    2017-11-01

    Image quality specifications should aimed to fulfil high resolution mission requirements of remote sensing satellites with a minimum cost. The most important trade-off to be taken into account is between Modulation Transfer Function, radiometric noise and sampling scheme. This compromise is the main driver during design optimisation and requirement definition in order to achieve good performances and to minimise the mission cost. For the SPOT 5 satellite, a new compromise had been chosen. The supermode principle of imagery (sampling at 2.5 meter with a pixel size of 5 meter) imp roves the resolution by a factor of four compared with the SPOT 4 satellite (10 meter resolution). This paper presents the image quality specifications of the HRG-SPOT 5 instrument. We introduce all the efforts made on the instrument to achieve good image quality and low radiometric noise, then we compare the results with the SPOT 4 instrument's performances to highlight the improvements achieved. Then, the in-orbit performance will be described. Finally, we will present the new goals of image quality specifications for the new Pleiades-HR satellite for earth observation (0.7 meter resolution) and the instrument concept.

  15. Ascertaining serum levels of trace elements in melanoma patients using PIXE and HR-ICPMS

    Science.gov (United States)

    Bernardes, S.; Tabacniks, M. H.; Santos, I. D. A. O.; Oliveira, A. F.; Shie, J. N.; Sarkis, J. E. S.; Oliveira, T.

    2014-01-01

    Melanoma is a serious and deadly form of skin cancer. However, patients' chances of survival and recovery are considerably increased when it is diagnosed and treated in its early stages. In this study, trace element concentrations in serum samples from patients with melanoma were measured using PIXE (Proton Induced X-ray Emission) and HR-ICPMS (High-Resolution Inductively Coupled Plasma Mass Spectrometry), with the purpose of correlating these concentrations with the disease. Blood samples from 30 melanoma patients and 116 healthy donors were collected at São Paulo Hospital (protocol CEP 1036/08 UNIFESP). Relevant clinical information on the patients has also been included in the statistical analysis. Analysis of the control group showed different P and Mg concentrations in individuals above and below 40 years of age. P, S, Ca, Cu and Zn concentrations in healthy individuals differed according to gender, highlighting the necessity to include age and gender variables in the case-control analysis. There were also differences in K, S, Ca and Se concentrations between the control and melanoma groups.

  16. Ascertaining serum levels of trace elements in melanoma patients using PIXE and HR-ICPMS

    Energy Technology Data Exchange (ETDEWEB)

    Bernardes, S., E-mail: suene@if.usp.br [Physics Institute, University of São Paulo (Brazil); Tabacniks, M.H. [Physics Institute, University of São Paulo (Brazil); Santos, I.D.A.O.; Oliveira, A.F.; Shie, J.N. [São Paulo Federal University (UNIFESP), São Paulo (Brazil); Sarkis, J.E.S.; Oliveira, T. [Institute of Energy and Nuclear Research (IPEN), Laboratory of Chemical Characterization (LCQ), Center for Chemistry and the Environment - CQMA, Sao Paulo (Brazil)

    2014-01-01

    Melanoma is a serious and deadly form of skin cancer. However, patients’ chances of survival and recovery are considerably increased when it is diagnosed and treated in its early stages. In this study, trace element concentrations in serum samples from patients with melanoma were measured using PIXE (Proton Induced X-ray Emission) and HR-ICPMS (High-Resolution Inductively Coupled Plasma Mass Spectrometry), with the purpose of correlating these concentrations with the disease. Blood samples from 30 melanoma patients and 116 healthy donors were collected at São Paulo Hospital (protocol CEP 1036/08 UNIFESP). Relevant clinical information on the patients has also been included in the statistical analysis. Analysis of the control group showed different P and Mg concentrations in individuals above and below 40 years of age. P, S, Ca, Cu and Zn concentrations in healthy individuals differed according to gender, highlighting the necessity to include age and gender variables in the case-control analysis. There were also differences in K, S, Ca and Se concentrations between the control and melanoma groups.

  17. Luminous and Variable Stars in M31 and M33. V. The Upper HR Diagram

    Energy Technology Data Exchange (ETDEWEB)

    Humphreys, Roberta M.; Davidson, Kris; Hahn, David [Minnesota Institute for Astrophysics, 116 Church St SE, University of Minnesota, Minneapolis, MN 55455 (United States); Martin, John C. [Barber Observatory, University of Illinois, Springfield, IL 62703 (United States); Weis, Kerstin, E-mail: roberta@umn.edu [Astronomical Institute, Ruhr-Universitaet Bochum (Germany)

    2017-07-20

    We present HR diagrams for the massive star populations in M31 and M33, including several different types of emission-line stars: the confirmed luminous blue variables (LBVs), candidate LBVs, B[e] supergiants, and the warm hypergiants. We estimate their apparent temperatures and luminosities for comparison with their respective massive star populations and evaluate the possible relationships of these different classes of evolved, massive stars, and their evolutionary state. Several of the LBV candidates lie near the LBV/S Dor instability strip that supports their classification. Most of the B[e] supergiants, however, are less luminous than the LBVs. Many are very dusty with the infrared flux contributing one-third or more to their total flux. They are also relatively isolated from other luminous OB stars. Overall, their spatial distribution suggests a more evolved state. Some may be post-RSGs (red supergiants) like the warm hypergiants, and there may be more than one path to becoming a B[e] star. There are sufficient differences in the spectra, luminosities, spatial distribution, and the presence or lack of dust between the LBVs and B[e] supergiants to conclude that one group does not evolve into the other.

  18. HR-EELS study of hydrogen bonding configuration, chemical and thermal stability of detonation nanodiamond films

    Energy Technology Data Exchange (ETDEWEB)

    Michaelson, Sh.; Akhvlediani, R. [Schulich Faculty of Chemistry, Technion-Israel Institute of Technology, Haifa 32000 (Israel); Petit, T.; Girard, H.A.; Arnault, J.C. [CEA, LIST, Diamond Sensors Laboratory, F-91191 Gif sur Yvette (France); Hoffman, A., E-mail: choffman@tx.technion.ac.il [Schulich Faculty of Chemistry, Technion-Israel Institute of Technology, Haifa 32000 (Israel)

    2014-06-01

    Nano-diamond films composed of 3–10 nm grains prepared by the detonation method and deposited onto silicon substrates by drop-casting were examined by high resolution electron energy loss spectroscopy (HR-EELS), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM) and secondary ion mass spectroscopy (SIMS). The impact of (i) ex-situ ambient annealing at 400 °C and (ii) ex-situ hydrogenation on hydrogen bonding and its thermal stability were examined. In order to clarify the changes in hydrogen bonding configuration detected on the different surfaces as a function of thermal annealing, in-situ hydrogenation by thermally activated atomic hydrogen was performed and examined. This study provides direct evidence that the exposure to ambient conditions and medium temperature ambient annealing have a pronounced effect on the hydrogen-carbon bonding configuration onto the nano-diamond surfaces. In-situ 1000 °C annealing results in irreversible changes of the film surface and partial nano-diamond silicidation.

  19. Urban Area Extent Extraction in Spaceborne HR and VHR Data Using Multi-Resolution Features

    Directory of Open Access Journals (Sweden)

    Gianni Cristian Iannelli

    2014-09-01

    Full Text Available Detection of urban area extents by means of remotely sensed data is a difficult task, especially because of the multiple, diverse definitions of what an “urban area” is. The models of urban areas listed in technical literature are based on the combination of spectral information with spatial patterns, possibly at different spatial resolutions. Starting from the same data set, “urban area” extraction may thus lead to multiple outputs. If this is done in a well-structured framework, however, this may be considered as an advantage rather than an issue. This paper proposes a novel framework for urban area extent extraction from multispectral Earth Observation (EO data. The key is to compute and combine spectral and multi-scale spatial features. By selecting the most adequate features, and combining them with proper logical rules, the approach allows matching multiple urban area models. Experimental results for different locations in Brazil and Kenya using High-Resolution (HR data prove the usefulness and flexibility of the framework.

  20. Determination of lead in rice grains by solid sampling HR-CS GFAAS.

    Science.gov (United States)

    Gunduz, Sema; Akman, Suleyman

    2013-12-01

    A study was performed for the determination of lead in rice grains directly by solid sampling high resolution continuum source graphite furnace atomic absorption spectrometry (HR-CS GFAAS) without digesting sample. The effects of sample amount, pyrolysis/atomization temperatures on the determination of lead in rice were investigated and optimized using a certificated rice flour. The lead concentrations were determined applying 800 °C of pyrolysis and 1800 °C of atomization temperatures without modifier. LOD (N=10, 3σ) and characteristic mass were 2.3 μg kg(-1) and 8.1 pg, respectively. The certified lead value of a rice flour CRM was found in its uncertainity limits. The lead contents of various rice samples obtained from markets in Turkey were between 0.009 and 0.162 mg kg(-1) which are in acceptable range. The average lead concentrations in various rice grains taken from the same package were significantly different from each other. Copyright © 2013 Elsevier Ltd. All rights reserved.