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Sample records for host-microbe interaction systems

  1. Host-microbe interactions in the gut of Drosophila melanogaster

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    Takayuki eKuraishi

    2013-12-01

    Full Text Available Many insect species subsist on decaying and contaminated matter and are thus exposed to large quantities of microorganisms. To control beneficial commensals and combat infectious pathogens, insects must be armed with efficient systems for microbial recognition, signaling pathways, and effector molecules. The molecular mechanisms regulating these host-microbe interactions in insects have been largely clarified in Drosophila melanogaster with its powerful genetic and genomic tools. Here we review recent advances in this field, focusing mainly on the relationships between microbes and epithelial cells in the intestinal tract where the host exposure to the external environment is most frequent.

  2. Host-Microbe Interactions in Microgravity: Assessment and Implications

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    Jamie S. Foster

    2014-05-01

    Full Text Available Spaceflight imposes several unique stresses on biological life that together can have a profound impact on the homeostasis between eukaryotes and their associated microbes. One such stressor, microgravity, has been shown to alter host-microbe interactions at the genetic and physiological levels. Recent sequencing of the microbiomes associated with plants and animals have shown that these interactions are essential for maintaining host health through the regulation of several metabolic and immune responses. Disruptions to various environmental parameters or community characteristics may impact the resiliency of the microbiome, thus potentially driving host-microbe associations towards disease. In this review, we discuss our current understanding of host-microbe interactions in microgravity and assess the impact of this unique environmental stress on the normal physiological and genetic responses of both pathogenic and mutualistic associations. As humans move beyond our biosphere and undergo longer duration space flights, it will be essential to more fully understand microbial fitness in microgravity conditions in order to maintain a healthy homeostasis between humans, plants and their respective microbiomes.

  3. Host-microbe interactions in microgravity: assessment and implications.

    Science.gov (United States)

    Foster, Jamie S; Wheeler, Raymond M; Pamphile, Regine

    2014-05-26

    Spaceflight imposes several unique stresses on biological life that together can have a profound impact on the homeostasis between eukaryotes and their associated microbes. One such stressor, microgravity, has been shown to alter host-microbe interactions at the genetic and physiological levels. Recent sequencing of the microbiomes associated with plants and animals have shown that these interactions are essential for maintaining host health through the regulation of several metabolic and immune responses. Disruptions to various environmental parameters or community characteristics may impact the resiliency of the microbiome, thus potentially driving host-microbe associations towards disease. In this review, we discuss our current understanding of host-microbe interactions in microgravity and assess the impact of this unique environmental stress on the normal physiological and genetic responses of both pathogenic and mutualistic associations. As humans move beyond our biosphere and undergo longer duration space flights, it will be essential to more fully understand microbial fitness in microgravity conditions in order to maintain a healthy homeostasis between humans, plants and their respective microbiomes.

  4. The role of lipids in host microbe interactions.

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    Lang, Roland; Mattner, Jochen

    2017-06-01

    Lipids are one of the major subcellular constituents and serve as signal molecules, energy sources, metabolic precursors and structural membrane components in various organisms. The function of lipids can be modified by multiple biochemical processes such as (de-)phosphorylation or (de-)glycosylation, and the organization of fatty acids into distinct cellular pools and subcellular compartments plays a pivotal role for the morphology and function of various cell populations. Thus, lipids regulate, for example, phagosome formation and maturation within host cells and thus, are critical for the elimination of microbial pathogens. Vice versa, microbial pathogens can manipulate the lipid composition of phagosomal membranes in host cells, and thus avoid their delivery to phagolysosomes. Lipids of microbial origin belong also to the strongest and most versatile inducers of mammalian immune responses upon engagement of distinct receptors on myeloid and lymphoid cells. Furthermore, microbial lipid toxins can induce membrane injuries and cell death. Thus, we will review here selected examples for mutual host-microbe interactions within the broad and divergent universe of lipids in microbial defense, tissue injury and immune evasion.

  5. Bactericidal Permeability-Increasing Proteins Shape Host-Microbe Interactions

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    Fangmin Chen

    2017-04-01

    Full Text Available We characterized bactericidal permeability-increasing proteins (BPIs of the squid Euprymna scolopes, EsBPI2 and EsBPI4. They have molecular characteristics typical of other animal BPIs, are closely related to one another, and nest phylogenetically among invertebrate BPIs. Purified EsBPIs had antimicrobial activity against the squid’s symbiont, Vibrio fischeri, which colonizes light organ crypt epithelia. Activity of both proteins was abrogated by heat treatment and coincubation with specific antibodies. Pretreatment under acidic conditions similar to those during symbiosis initiation rendered V. fischeri more resistant to the antimicrobial activity of the proteins. Immunocytochemistry localized EsBPIs to the symbiotic organ and other epithelial surfaces interacting with ambient seawater. The proteins differed in intracellular distribution. Further, whereas EsBPI4 was restricted to epithelia, EsBPI2 also occurred in blood and in a transient juvenile organ that mediates hatching. The data provide evidence that these BPIs play different defensive roles early in the life of E. scolopes, modulating interactions with the symbiont.

  6. Protein interaction networks at the host-microbe interface in Diaphorina citri, the insect vector of the citrus greening pathogen.

    Science.gov (United States)

    Ramsey, J S; Chavez, J D; Johnson, R; Hosseinzadeh, S; Mahoney, J E; Mohr, J P; Robison, F; Zhong, X; Hall, D G; MacCoss, M; Bruce, J; Cilia, M

    2017-02-01

    The Asian citrus psyllid ( Diaphorina citri) is the insect vector responsible for the worldwide spread of ' Candidatus Liberibacter asiaticus' (CLas), the bacterial pathogen associated with citrus greening disease. Developmental changes in the insect vector impact pathogen transmission, such that D. citri transmission of CLas is more efficient when bacteria are acquired by nymphs when compared with adults. We hypothesize that expression changes in the D. citri immune system and commensal microbiota occur during development and regulate vector competency. In support of this hypothesis, more proteins, with greater fold changes, were differentially expressed in response to CLas in adults when compared with nymphs, including insect proteins involved in bacterial adhesion and immunity. Compared with nymphs, adult insects had a higher titre of CLas and the bacterial endosymbionts Wolbachia, Profftella and Carsonella. All Wolbachia and Profftella proteins differentially expressed between nymphs and adults are upregulated in adults, while most differentially expressed Carsonella proteins are upregulated in nymphs. Discovery of protein interaction networks has broad applicability to the study of host-microbe relationships. Using protein interaction reporter technology, a D. citri haemocyanin protein highly upregulated in response to CLas was found to physically interact with the CLas coenzyme A (CoA) biosynthesis enzyme phosphopantothenoylcysteine synthetase/decarboxylase. CLas pantothenate kinase, which catalyses the rate-limiting step of CoA biosynthesis, was found to interact with a D. citri myosin protein. Two Carsonella enzymes involved in histidine and tryptophan biosynthesis were found to physically interact with D. citri proteins. These co-evolved protein interaction networks at the host-microbe interface are highly specific targets for controlling the insect vector responsible for the spread of citrus greening.

  7. Friends with Social Benefits: Host-Microbe Interactions as a Driver of Brain Evolution and Development?

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    Roman M Stilling

    2014-10-01

    Full Text Available The tight association of the human body with trillions of colonizing microbes that we observe today is the result of a long evolutionary history. Only very recently have we started to understand how this symbiosis also affects brain function and behaviour. Here in this hypothesis and theory article, we propose how host-microbe associations potentially influenced mammalian brain evolution and development. In particular, we explore the integration of human brain development with evolution, symbiosis, and RNA biology, which together represent a ‘social triangle’ that drives human social behaviour and cognition. We argue that, in order to understand how inter-kingdom communication can affect brain adaptation and plasticity, it is inevitable to consider epigenetic mechanisms as important mediators of genome-microbiome interactions on an individual as well as a transgenerational time scale. Finally, we unite these interpretations with the hologenome theory of evolution. Taken together, we propose a tighter integration of neuroscience fields with host-associated microbiology by taking an evolutionary perspective.

  8. The Road to Infection: Host-Microbe Interactions Defining the Pathogenicity of Streptococcus bovis/Streptococcus equinus Complex Members

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    Christoph Jans

    2018-04-01

    Full Text Available The Streptococcus bovis/Streptococcus equinus complex (SBSEC comprises several species inhabiting the animal and human gastrointestinal tract (GIT. They match the pathobiont description, are potential zoonotic agents and technological organisms in fermented foods. SBSEC members are associated with multiple diseases in humans and animals including ruminal acidosis, infective endocarditis (IE and colorectal cancer (CRC. Therefore, this review aims to re-evaluate adhesion and colonization abilities of SBSEC members of animal, human and food origin paired with genomic and functional host-microbe interaction data on their road from colonization to infection. SBSEC seem to be a marginal population during GIT symbiosis that can proliferate as opportunistic pathogens. Risk factors for human colonization are considered living in rural areas and animal-feces contact. Niche adaptation plays a pivotal role where Streptococcus gallolyticus subsp. gallolyticus (SGG retained the ability to proliferate in various environments. Other SBSEC members have undergone genome reduction and niche-specific gene gain to yield important commensal, pathobiont and technological species. Selective colonization of CRC tissue is suggested for SGG, possibly related to increased adhesion to cancerous cell types featuring enhanced collagen IV accessibility. SGG can colonize, proliferate and may shape the tumor microenvironment to their benefit by tumor promotion upon initial neoplasia development. Bacteria cell surface structures including lipotheichoic acids, capsular polysaccharides and pilus loci (pil1, pil2, and pil3 govern adhesion. Only human blood-derived SGG contain complete pilus loci and other disease-associated surface proteins. Rumen or feces-derived SGG and other SBSEC members lack or harbor mutated pili. Pili also contribute to binding to fibrinogen upon invasion and translocation of cells from the GIT into the blood system, subsequent immune evasion, human contact

  9. The Road to Infection: Host-Microbe Interactions Defining the Pathogenicity of Streptococcus bovis/Streptococcus equinus Complex Members

    Science.gov (United States)

    Jans, Christoph; Boleij, Annemarie

    2018-01-01

    The Streptococcus bovis/Streptococcus equinus complex (SBSEC) comprises several species inhabiting the animal and human gastrointestinal tract (GIT). They match the pathobiont description, are potential zoonotic agents and technological organisms in fermented foods. SBSEC members are associated with multiple diseases in humans and animals including ruminal acidosis, infective endocarditis (IE) and colorectal cancer (CRC). Therefore, this review aims to re-evaluate adhesion and colonization abilities of SBSEC members of animal, human and food origin paired with genomic and functional host-microbe interaction data on their road from colonization to infection. SBSEC seem to be a marginal population during GIT symbiosis that can proliferate as opportunistic pathogens. Risk factors for human colonization are considered living in rural areas and animal-feces contact. Niche adaptation plays a pivotal role where Streptococcus gallolyticus subsp. gallolyticus (SGG) retained the ability to proliferate in various environments. Other SBSEC members have undergone genome reduction and niche-specific gene gain to yield important commensal, pathobiont and technological species. Selective colonization of CRC tissue is suggested for SGG, possibly related to increased adhesion to cancerous cell types featuring enhanced collagen IV accessibility. SGG can colonize, proliferate and may shape the tumor microenvironment to their benefit by tumor promotion upon initial neoplasia development. Bacteria cell surface structures including lipotheichoic acids, capsular polysaccharides and pilus loci (pil1, pil2, and pil3) govern adhesion. Only human blood-derived SGG contain complete pilus loci and other disease-associated surface proteins. Rumen or feces-derived SGG and other SBSEC members lack or harbor mutated pili. Pili also contribute to binding to fibrinogen upon invasion and translocation of cells from the GIT into the blood system, subsequent immune evasion, human contact system

  10. The bee microbiome: Impact on bee health and model for evolution and ecology of host-microbe interactions

    Science.gov (United States)

    Engel, Philipp; Kwong, Waldan K.; McFrederick, Quinn; Anderson, Kirk E.; Barribeau, Seth Michael; Chandler, James Angus; Cornman, Robert S.; Dainat, Jacques; de Miranda, Joachim R.; Doublet, Vincent; Emery, Olivier; Evans, Jay D.; Farinelli, Laurent; Flenniken, Michelle L.; Granberg, Fredrik; Grasis, Juris A.; Gauthier, Laurent; Hayer, Juliette; Koch, Hauke; Kocher, Sarah; Martinson, Vincent G.; Moran, Nancy; Munoz-Torres, Monica; Newton, Irene; Paxton, Robert J.; Powell, Eli; Sadd, Ben M.; Schmid-Hempel, Paul; Schmid-Hempel, Regula; Song, Se Jin; Schwarz, Ryan S.; vanEngelsdorp, Dennis; Dainat, Benjamin

    2016-01-01

    As pollinators, bees are cornerstones for terrestrial ecosystem stability and key components in agricultural productivity. All animals, including bees, are associated with a diverse community of microbes, commonly referred to as the microbiome. The bee microbiome is likely to be a crucial factor affecting host health. However, with the exception of a few pathogens, the impacts of most members of the bee microbiome on host health are poorly understood. Further, the evolutionary and ecological forces that shape and change the microbiome are unclear. Here, we discuss recent progress in our understanding of the bee microbiome, and we present challenges associated with its investigation. We conclude that global coordination of research efforts is needed to fully understand the complex and highly dynamic nature of the interplay between the bee microbiome, its host, and the environment. High-throughput sequencing technologies are ideal for exploring complex biological systems, including host-microbe interactions. To maximize their value and to improve assessment of the factors affecting bee health, sequence data should be archived, curated, and analyzed in ways that promote the synthesis of different studies. To this end, the BeeBiome consortium aims to develop an online database which would provide reference sequences, archive metadata, and host analytical resources. The goal would be to support applied and fundamental research on bees and their associated microbes and to provide a collaborative framework for sharing primary data from different research programs, thus furthering our understanding of the bee microbiome and its impact on pollinator health.

  11. The Bee Microbiome: Impact on Bee Health and Model for Evolution and Ecology of Host-Microbe Interactions

    Directory of Open Access Journals (Sweden)

    Philipp Engel

    2016-05-01

    Full Text Available As pollinators, bees are cornerstones for terrestrial ecosystem stability and key components in agricultural productivity. All animals, including bees, are associated with a diverse community of microbes, commonly referred to as the microbiome. The bee microbiome is likely to be a crucial factor affecting host health. However, with the exception of a few pathogens, the impacts of most members of the bee microbiome on host health are poorly understood. Further, the evolutionary and ecological forces that shape and change the microbiome are unclear. Here, we discuss recent progress in our understanding of the bee microbiome, and we present challenges associated with its investigation. We conclude that global coordination of research efforts is needed to fully understand the complex and highly dynamic nature of the interplay between the bee microbiome, its host, and the environment. High-throughput sequencing technologies are ideal for exploring complex biological systems, including host-microbe interactions. To maximize their value and to improve assessment of the factors affecting bee health, sequence data should be archived, curated, and analyzed in ways that promote the synthesis of different studies. To this end, the BeeBiome consortium aims to develop an online database which would provide reference sequences, archive metadata, and host analytical resources. The goal would be to support applied and fundamental research on bees and their associated microbes and to provide a collaborative framework for sharing primary data from different research programs, thus furthering our understanding of the bee microbiome and its impact on pollinator health.

  12. The Bee Microbiome: Impact on Bee Health and Model for Evolution and Ecology of Host-Microbe Interactions.

    Science.gov (United States)

    Engel, Philipp; Kwong, Waldan K; McFrederick, Quinn; Anderson, Kirk E; Barribeau, Seth Michael; Chandler, James Angus; Cornman, R Scott; Dainat, Jacques; de Miranda, Joachim R; Doublet, Vincent; Emery, Olivier; Evans, Jay D; Farinelli, Laurent; Flenniken, Michelle L; Granberg, Fredrik; Grasis, Juris A; Gauthier, Laurent; Hayer, Juliette; Koch, Hauke; Kocher, Sarah; Martinson, Vincent G; Moran, Nancy; Munoz-Torres, Monica; Newton, Irene; Paxton, Robert J; Powell, Eli; Sadd, Ben M; Schmid-Hempel, Paul; Schmid-Hempel, Regula; Song, Se Jin; Schwarz, Ryan S; vanEngelsdorp, Dennis; Dainat, Benjamin

    2016-04-26

    As pollinators, bees are cornerstones for terrestrial ecosystem stability and key components in agricultural productivity. All animals, including bees, are associated with a diverse community of microbes, commonly referred to as the microbiome. The bee microbiome is likely to be a crucial factor affecting host health. However, with the exception of a few pathogens, the impacts of most members of the bee microbiome on host health are poorly understood. Further, the evolutionary and ecological forces that shape and change the microbiome are unclear. Here, we discuss recent progress in our understanding of the bee microbiome, and we present challenges associated with its investigation. We conclude that global coordination of research efforts is needed to fully understand the complex and highly dynamic nature of the interplay between the bee microbiome, its host, and the environment. High-throughput sequencing technologies are ideal for exploring complex biological systems, including host-microbe interactions. To maximize their value and to improve assessment of the factors affecting bee health, sequence data should be archived, curated, and analyzed in ways that promote the synthesis of different studies. To this end, the BeeBiome consortium aims to develop an online database which would provide reference sequences, archive metadata, and host analytical resources. The goal would be to support applied and fundamental research on bees and their associated microbes and to provide a collaborative framework for sharing primary data from different research programs, thus furthering our understanding of the bee microbiome and its impact on pollinator health. Copyright © 2016 Engel et al.

  13. Host-microbe interactions that shape the pathogenesis of Acinetobacter baumannii infection

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    Mortensen, Brittany L.; Skaar, Eric P.

    2013-01-01

    Summary Acinetobacter baumannii is an opportunistic pathogen that has emerged as a prevalent source of nosocomial infections, most frequently causing ventilator-associated pneumonia. The emergence of pan-drug resistant strains magnifies the problem by reducing viable treatment options and effectively increasing the mortality rate associated with Acinetobacter infections. In light of this rising threat, research on A. baumannii epidemiology, antibiotic resistance, and pathogenesis is accelerating. The recent development of both in vitro and in vivo models has enabled studies probing the host-Acinetobacter interface. Bacterial genetic screens and comparative genomic studies have led to the identification of several A. baumannii virulence factors. Additionally, investigations into host defense mechanisms using animal models or cell culture have provided insight into the innate immune response to infection. This review highlights some of the key attributes of A. baumannii virulence with an emphasis on bacterial interactions with the innate immune system. PMID:22640368

  14. Host-microbe and microbe-microbe interactions in the evolution of obligate plant parasitism.

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    Kemen, Ariane C; Agler, Matthew T; Kemen, Eric

    2015-06-01

    Research on obligate biotrophic plant parasites, which reproduce only on living hosts, has revealed a broad diversity of filamentous microbes that have independently acquired complex morphological structures, such as haustoria. Genome studies have also demonstrated a concerted loss of genes for metabolism and lytic enzymes, and gain of diversity of genes coding for effectors involved in host defense suppression. So far, these traits converge in all known obligate biotrophic parasites, but unexpected genome plasticity remains. This plasticity is manifested as transposable element (TE)-driven increases in genome size, observed to be associated with the diversification of virulence genes under selection pressure. Genome expansion could result from the governing of the pathogen response to ecological selection pressures, such as host or nutrient availability, or to microbial interactions, such as competition, hyperparasitism and beneficial cooperations. Expansion is balanced by alternating sexual and asexual cycles, as well as selfing and outcrossing, which operate to control transposon activity in populations. In turn, the prevalence of these balancing mechanisms seems to be correlated with external biotic factors, suggesting a complex, interconnected evolutionary network in host-pathogen-microbe interactions. Therefore, the next phase of obligate biotrophic pathogen research will need to uncover how this network, including multitrophic interactions, shapes the evolution and diversity of pathogens. © 2015 The Authors. New Phytologist © 2015 New Phytologist Trust.

  15. The role of gut microbiota in health and disease: In vitro modeling of host-microbe interactions at the aerobe-anaerobe interphase of the human gut.

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    von Martels, Julius Z H; Sadaghian Sadabad, Mehdi; Bourgonje, Arno R; Blokzijl, Tjasso; Dijkstra, Gerard; Faber, Klaas Nico; Harmsen, Hermie J M

    2017-04-01

    The microbiota of the gut has many crucial functions in human health. Dysbiosis of the microbiota has been correlated to a large and still increasing number of diseases. Recent studies have mostly focused on analyzing the associations between disease and an aberrant microbiota composition. Functional studies using (in vitro) gut models are required to investigate the precise interactions that occur between specific bacteria (or bacterial mixtures) and gut epithelial cells. As most gut bacteria are obligate or facultative anaerobes, studying their effect on oxygen-requiring human gut epithelial cells is technically challenging. Still, several (anaerobic) bacterial-epithelial co-culture systems have recently been developed that mimic host-microbe interactions occurring in the human gut, including 1) the Transwell "apical anaerobic model of the intestinal epithelial barrier", 2) the Host-Microbiota Interaction (HMI) module, 3) the "Human oxygen-Bacteria anaerobic" (HoxBan) system, 4) the human gut-on-a-chip and 5) the HuMiX model. This review discusses the role of gut microbiota in health and disease and gives an overview of the characteristics and applications of these novel host-microbe co-culture systems. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Nanovesicles from Malassezia sympodialis and host exosomes induce cytokine responses--novel mechanisms for host-microbe interactions in atopic eczema.

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    Ulf Gehrmann

    Full Text Available BACKGROUND: Intercellular communication can occur via the release of membrane vesicles. Exosomes are nanovesicles released from the endosomal compartment of cells. Depending on their cell of origin and their cargo they can exert different immunoregulatory functions. Recently, fungi were found to produce extracellular vesicles that can influence host-microbe interactions. The yeast Malassezia sympodialis which belongs to our normal cutaneous microbial flora elicits specific IgE- and T-cell reactivity in approximately 50% of adult patients with atopic eczema (AE. Whether exosomes or other vesicles contribute to the inflammation has not yet been investigated. OBJECTIVE: To investigate if M. sympodialis can release nanovesicles and whether they or endogenous exosomes can activate PBMC from AE patients sensitized to M. sympodialis. METHODS: Extracellular nanovesicles isolated from M. sympodialis, co-cultures of M. sympodialis and dendritic cells, and from plasma of patients with AE and healthy controls (HC were characterised using flow cytometry, sucrose gradient centrifugation, Western blot and electron microscopy. Their ability to stimulate IL-4 and TNF-alpha responses in autologous CD14, CD34 depleted PBMC was determined using ELISPOT and ELISA, respectively. RESULTS: We show for the first time that M. sympodialis releases extracellular vesicles carrying allergen. These vesicles can induce IL-4 and TNF-α responses with a significantly higher IL-4 production in patients compared to HC. Exosomes from dendritic cell and M. sympodialis co-cultures induced IL-4 and TNF-α responses in autologous CD14, CD34 depleted PBMC of AE patients and HC while plasma exosomes induced TNF-α but not IL-4 in undepleted PBMC. CONCLUSIONS: Extracellular vesicles from M. sympodialis, dendritic cells and plasma can contribute to cytokine responses in CD14, CD34 depleted and undepleted PBMC of AE patients and HC. These novel observations have implications for

  17. Disease susceptibiliy in the zig-zag model of host-microbe Interactions: only a consequence of immune suppression?

    OpenAIRE

    Keller, Harald; Boyer, Laurent; Abad, Pierre

    2016-01-01

    For almost ten years, the Zig-Zag model has provided a convenient framework for explaining the molecular bases of compatibility and incompatibility in plant-microbe interactions (Jones and Dangl, 2006). According to the Zig-Zag model, disease susceptibility is a consequence of the suppression of host immunity during the evolutionary arms race between plants and pathogens. The Zig-Zag model thus fits well with biotrophic interactions, but is less applicable to interactions involving pathogens ...

  18. A metasystem of framework model organisms to study emergence of new host-microbe adaptations.

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    Gopalan, Suresh; Ausubel, Frederick M

    2008-01-01

    An unintended consequence of global industrialization and associated societal rearrangements is new interactions of microbes and potential hosts (especially mammals and plants), providing an opportunity for the rapid emergence of host-microbe adaptation and eventual establishment of new microbe-related diseases. We describe a new model system comprising the model plant Arabidopsis thaliana and several microbes, each representing different modes of interaction, to study such "maladaptations". The model microbes include human and agricultural pathogens and microbes that are commonly considered innocuous. The system has a large knowledge base corresponding to each component organism and is amenable to high-throughput automation assisted perturbation screens for identifying components that modulate host-pathogen interactions. This would aid in the study of emergence and progression of host-microbe maladaptations in a controlled environment.

  19. Using structural knowledge in the protein data bank to inform the search for potential host-microbe protein interactions in sequence space: application to Mycobacterium tuberculosis.

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    Mahajan, Gaurang; Mande, Shekhar C

    2017-04-04

    A comprehensive map of the human-M. tuberculosis (MTB) protein interactome would help fill the gaps in our understanding of the disease, and computational prediction can aid and complement experimental studies towards this end. Several sequence-based in silico approaches tap the existing data on experimentally validated protein-protein interactions (PPIs); these PPIs serve as templates from which novel interactions between pathogen and host are inferred. Such comparative approaches typically make use of local sequence alignment, which, in the absence of structural details about the interfaces mediating the template interactions, could lead to incorrect inferences, particularly when multi-domain proteins are involved. We propose leveraging the domain-domain interaction (DDI) information in PDB complexes to score and prioritize candidate PPIs between host and pathogen proteomes based on targeted sequence-level comparisons. Our method picks out a small set of human-MTB protein pairs as candidates for physical interactions, and the use of functional meta-data suggests that some of them could contribute to the in vivo molecular cross-talk between pathogen and host that regulates the course of the infection. Further, we present numerical data for Pfam domain families that highlights interaction specificity on the domain level. Not every instance of a pair of domains, for which interaction evidence has been found in a few instances (i.e. structures), is likely to functionally interact. Our sorting approach scores candidates according to how "distant" they are in sequence space from known examples of DDIs (templates). Thus, it provides a natural way to deal with the heterogeneity in domain-level interactions. Our method represents a more informed application of local alignment to the sequence-based search for potential human-microbial interactions that uses available PPI data as a prior. Our approach is somewhat limited in its sensitivity by the restricted size and

  20. Genetic transformation of an obligate anaerobe, P. gingivalis for FMN-green fluorescent protein expression in studying host-microbe interaction.

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    Chul Hee Choi

    Full Text Available The recent introduction of "oxygen-independent" flavin mononucleotide (FMN-based fluorescent proteins (FbFPs is of major interest to both eukaryotic and prokaryotic microbial biologists. Accordingly, we demonstrate for the first time that an obligate anaerobe, the successful opportunistic pathogen of the oral cavity, Porphyromonas gingivalis, can be genetically engineered for expression of the non-toxic green FbFP. The resulting transformants are functional for studying dynamic bacterial processes in living host cells. The visualization of the transformed P. gingivalis (PgFbFP revealed strong fluorescence that reached a maximum emission at 495 nm as determined by fluorescence microscopy and spectrofluorometry. Human primary gingival epithelial cells (GECs were infected with PgFbFP and the bacterial invasion of host cells was analyzed by a quantitative fluorescence microscopy and antibiotic protection assays. The results showed similar levels of intracellular bacteria for both wild type and PgFbFP strains. In conjunction with organelle specific fluorescent dyes, utilization of the transformed strain provided direct and accurate determination of the live/metabolically active P. gingivalis' trafficking in the GECs over time. Furthermore, the GECs were co-infected with PgFbFP and the ATP-dependent Clp serine protease-deficient mutant (ClpP- to study the differential fates of the two strains within the same host cells. Quantitative co-localization analyses displayed the intracellular PgFbFP significantly associated with the endoplasmic reticulum network, whereas the majority of ClpP- organisms trafficked into the lysosomes. Hence, we have developed a novel and reliable method to characterize live host cell-microbe interactions and demonstrated the adaptability of FMN-green fluorescent protein for studying persistent host infections induced by obligate anaerobic organisms.

  1. Genetic transformation of an obligate anaerobe, P. gingivalis for FMN-green fluorescent protein expression in studying host-microbe interaction.

    Science.gov (United States)

    Choi, Chul Hee; DeGuzman, Jefferson V; Lamont, Richard J; Yilmaz, Özlem

    2011-04-15

    The recent introduction of "oxygen-independent" flavin mononucleotide (FMN)-based fluorescent proteins (FbFPs) is of major interest to both eukaryotic and prokaryotic microbial biologists. Accordingly, we demonstrate for the first time that an obligate anaerobe, the successful opportunistic pathogen of the oral cavity, Porphyromonas gingivalis, can be genetically engineered for expression of the non-toxic green FbFP. The resulting transformants are functional for studying dynamic bacterial processes in living host cells. The visualization of the transformed P. gingivalis (PgFbFP) revealed strong fluorescence that reached a maximum emission at 495 nm as determined by fluorescence microscopy and spectrofluorometry. Human primary gingival epithelial cells (GECs) were infected with PgFbFP and the bacterial invasion of host cells was analyzed by a quantitative fluorescence microscopy and antibiotic protection assays. The results showed similar levels of intracellular bacteria for both wild type and PgFbFP strains. In conjunction with organelle specific fluorescent dyes, utilization of the transformed strain provided direct and accurate determination of the live/metabolically active P. gingivalis' trafficking in the GECs over time. Furthermore, the GECs were co-infected with PgFbFP and the ATP-dependent Clp serine protease-deficient mutant (ClpP-) to study the differential fates of the two strains within the same host cells. Quantitative co-localization analyses displayed the intracellular PgFbFP significantly associated with the endoplasmic reticulum network, whereas the majority of ClpP- organisms trafficked into the lysosomes. Hence, we have developed a novel and reliable method to characterize live host cell-microbe interactions and demonstrated the adaptability of FMN-green fluorescent protein for studying persistent host infections induced by obligate anaerobic organisms.

  2. NetCooperate: a network-based tool for inferring host-microbe and microbe-microbe cooperation

    OpenAIRE

    Levy, Roie; Carr, Rogan; Kreimer, Anat; Freilich, Shiri; Borenstein, Elhanan

    2015-01-01

    Background Host-microbe and microbe-microbe interactions are often governed by the complex exchange of metabolites. Such interactions play a key role in determining the way pathogenic and commensal species impact their host and in the assembly of complex microbial communities. Recently, several studies have demonstrated how such interactions are reflected in the organization of the metabolic networks of the interacting species, and introduced various graph theory-based methods to predict host...

  3. NetCooperate: a network-based tool for inferring host-microbe and microbe-microbe cooperation.

    Science.gov (United States)

    Levy, Roie; Carr, Rogan; Kreimer, Anat; Freilich, Shiri; Borenstein, Elhanan

    2015-05-17

    Host-microbe and microbe-microbe interactions are often governed by the complex exchange of metabolites. Such interactions play a key role in determining the way pathogenic and commensal species impact their host and in the assembly of complex microbial communities. Recently, several studies have demonstrated how such interactions are reflected in the organization of the metabolic networks of the interacting species, and introduced various graph theory-based methods to predict host-microbe and microbe-microbe interactions directly from network topology. Using these methods, such studies have revealed evolutionary and ecological processes that shape species interactions and community assembly, highlighting the potential of this reverse-ecology research paradigm. NetCooperate is a web-based tool and a software package for determining host-microbe and microbe-microbe cooperative potential. It specifically calculates two previously developed and validated metrics for species interaction: the Biosynthetic Support Score which quantifies the ability of a host species to supply the nutritional requirements of a parasitic or a commensal species, and the Metabolic Complementarity Index which quantifies the complementarity of a pair of microbial organisms' niches. NetCooperate takes as input a pair of metabolic networks, and returns the pairwise metrics as well as a list of potential syntrophic metabolic compounds. The Biosynthetic Support Score and Metabolic Complementarity Index provide insight into host-microbe and microbe-microbe metabolic interactions. NetCooperate determines these interaction indices from metabolic network topology, and can be used for small- or large-scale analyses. NetCooperate is provided as both a web-based tool and an open-source Python module; both are freely available online at http://elbo.gs.washington.edu/software_netcooperate.html.

  4. Organoid culture systems to study host-pathogen interactions

    NARCIS (Netherlands)

    Dutta, Devanjali; Clevers, Hans

    2017-01-01

    Recent advances in host-microbe interaction studies in organoid cultures have shown great promise and have laid the foundation for much more refined future studies using these systems. Modeling of Zika virus (ZIKV) infection in cerebral organoids have helped us understand its association with

  5. A place for host-microbe symbiosis in the comparative physiologist's toolbox.

    Science.gov (United States)

    Kohl, Kevin D; Carey, Hannah V

    2016-11-15

    Although scientists have long appreciated that metazoans evolved in a microbial world, we are just beginning to appreciate the profound impact that host-associated microbes have on diverse aspects of animal biology. The enormous growth in our understanding of host-microbe symbioses is rapidly expanding the study of animal physiology, both technically and conceptually. Microbes associate functionally with various body surfaces of their hosts, although most reside in the gastrointestinal tract. Gut microbes convert dietary and host-derived substrates to metabolites such as short-chain fatty acids, thereby providing energy and nutrients to the host. Bacterial metabolites incorporated into the host metabolome can activate receptors on a variety of cell types and, in doing so, alter host physiology (including metabolism, organ function, biological rhythms, neural activity and behavior). Given that host-microbe interactions affect diverse aspects of host physiology, it is likely that they influence animal ecology and, if they confer fitness benefits, the evolutionary trajectory of a species. Multiple variables - including sampling regime, environmental parameters, host metadata and analytical methods - can influence experimental outcomes in host-microbiome studies, making careful experimental design and execution crucial to ensure reproducible and informative studies in the laboratory and field. Integration of microbiomes into comparative physiology and ecophysiological investigations can reveal the potential impacts of the microbiota on physiological responses to changing environments, and is likely to bring valuable insights to the study of host-microbiome interactions among a broad range of metazoans, including humans. © 2016. Published by The Company of Biologists Ltd.

  6. Extracellular vesicles modulate host-microbe responses by altering TLR2 activity and phagocytosis.

    Directory of Open Access Journals (Sweden)

    Jeroen van Bergenhenegouwen

    Full Text Available Oral delivery of Gram positive bacteria, often derived from the genera Lactobacillus or Bifidobacterium, can modulate immune function. Although the exact mechanisms remain unclear, immunomodulatory effects may be elicited through the direct interaction of these bacteria with the intestinal epithelium or resident dendritic cell (DC populations. We analyzed the immune activation properties of Lactobacilli and Bifidobacterium species and made the surprising observation that cellular responses in vitro were differentially influenced by the presence of serum, specifically the extracellular vesicle (EV fraction. In contrast to the tested Lactobacilli species, tested Bifidobacterium species induce TLR2/6 activity which is inhibited by the presence of EVs. Using specific TLR ligands, EVs were found to enhance cellular TLR2/1 and TLR4 responses while TLR2/6 responses were suppressed. No effect could be observed on cellular TLR5 responses. We determined that EVs play a role in bacterial aggregation, suggesting that EVs interact with bacterial surfaces. EVs were found to slightly enhance DC phagocytosis of Bifidobacterium breve whereas phagocytosis of Lactobacillus rhamnosus was virtually absent upon serum EV depletion. DC uptake of a non-microbial substance (dextran was not affected by the different serum fractions suggesting that EVs do not interfere with DC phagocytic capacity but rather modify the DC-microbe interaction. Depending on the microbe, combined effects of EVs on TLR activity and phagocytosis result in a differential proinflammatory DC cytokine release. Overall, these data suggest that EVs play a yet unrecognized role in host-microbe responses, not by interfering in recipient cellular responses but via attachment to, or scavenging of, microbe-associated molecular patterns. EVs can be found in any tissue or bodily fluid, therefore insights into EV-microbe interactions are important in understanding the mechanism of action of potential

  7. Dual oxidase in mucosal immunity and host-microbe homeostasis.

    Science.gov (United States)

    Bae, Yun Soo; Choi, Myoung Kwon; Lee, Won-Jae

    2010-07-01

    Mucosal epithelia are in direct contact with microbes, which range from beneficial symbionts to pathogens. Accordingly, hosts must have a conflicting strategy to combat pathogens efficiently while tolerating symbionts. Recent progress has revealed that dual oxidase (DUOX) plays a key role in mucosal immunity in organisms that range from flies to humans. Information from the genetic model of Drosophila has advanced our understanding of the regulatory mechanism of DUOX and its role in mucosal immunity. Further investigations of DUOX regulation in response to symbiotic or non-symbiotic bacteria and the in vivo consequences in host physiology will give a novel insight into the microbe-controlling system of the mucosa. Copyright 2010 Elsevier Ltd. All rights reserved.

  8. Formation of a symbiotic host-microbe interface: the role of SNARE-mediated regulation of exocytosis

    NARCIS (Netherlands)

    Huisman, Rik

    2018-01-01

    At the heart of endosymbiosis microbes are hosted inside living cells in specialized membrane compartments that from a host-microbe interface, where nutrients and signal are efficiently exchanged. Such symbiotic interfaces include arbuscules produced by arbuscular mycorrhiza (AM) and

  9. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

    Science.gov (United States)

    Jostins, Luke; Ripke, Stephan; Weersma, Rinse K; Duerr, Richard H; McGovern, Dermot P; Hui, Ken Y; Lee, James C; Schumm, L Philip; Sharma, Yashoda; Anderson, Carl A; Essers, Jonah; Mitrovic, Mitja; Ning, Kaida; Cleynen, Isabelle; Theatre, Emilie; Spain, Sarah L; Raychaudhuri, Soumya; Goyette, Philippe; Wei, Zhi; Abraham, Clara; Achkar, Jean-Paul; Ahmad, Tariq; Amininejad, Leila; Ananthakrishnan, Ashwin N; Andersen, Vibeke; Andrews, Jane M; Baidoo, Leonard; Balschun, Tobias; Bampton, Peter A; Bitton, Alain; Boucher, Gabrielle; Brand, Stephan; Büning, Carsten; Cohain, Ariella; Cichon, Sven; D’Amato, Mauro; De Jong, Dirk; Devaney, Kathy L; Dubinsky, Marla; Edwards, Cathryn; Ellinghaus, David; Ferguson, Lynnette R; Franchimont, Denis; Fransen, Karin; Gearry, Richard; Georges, Michel; Gieger, Christian; Glas, Jürgen; Haritunians, Talin; Hart, Ailsa; Hawkey, Chris; Hedl, Matija; Hu, Xinli; Karlsen, Tom H; Kupcinskas, Limas; Kugathasan, Subra; Latiano, Anna; Laukens, Debby; Lawrance, Ian C; Lees, Charlie W; Louis, Edouard; Mahy, Gillian; Mansfield, John; Morgan, Angharad R; Mowat, Craig; Newman, William; Palmieri, Orazio; Ponsioen, Cyriel Y; Potocnik, Uros; Prescott, Natalie J; Regueiro, Miguel; Rotter, Jerome I; Russell, Richard K; Sanderson, Jeremy D; Sans, Miquel; Satsangi, Jack; Schreiber, Stefan; Simms, Lisa A; Sventoraityte, Jurgita; Targan, Stephan R; Taylor, Kent D; Tremelling, Mark; Verspaget, Hein W; De Vos, Martine; Wijmenga, Cisca; Wilson, David C; Winkelmann, Juliane; Xavier, Ramnik J; Zeissig, Sebastian; Zhang, Bin; Zhang, Clarence K; Zhao, Hongyu; Silverberg, Mark S; Annese, Vito; Hakonarson, Hakon; Brant, Steven R; Radford-Smith, Graham; Mathew, Christopher G; Rioux, John D; Schadt, Eric E; Daly, Mark J; Franke, Andre; Parkes, Miles; Vermeire, Severine; Barrett, Jeffrey C; Cho, Judy H

    2012-01-01

    Crohn’s disease (CD) and ulcerative colitis (UC), the two common forms of inflammatory bowel disease (IBD), affect over 2.5 million people of European ancestry with rising prevalence in other populations1. Genome-wide association studies (GWAS) and subsequent meta-analyses of CD and UC2,3 as separate phenotypes implicated previously unsuspected mechanisms, such as autophagy4, in pathogenesis and showed that some IBD loci are shared with other inflammatory diseases5. Here we expand knowledge of relevant pathways by undertaking a meta-analysis of CD and UC genome-wide association scans, with validation of significant findings in more than 75,000 cases and controls. We identify 71 new associations, for a total of 163 IBD loci that meet genome-wide significance thresholds. Most loci contribute to both phenotypes, and both directional and balancing selection effects are evident. Many IBD loci are also implicated in other immune-mediated disorders, most notably with ankylosing spondylitis and psoriasis. We also observe striking overlap between susceptibility loci for IBD and mycobacterial infection. Gene co-expression network analysis emphasizes this relationship, with pathways shared between host responses to mycobacteria and those predisposing to IBD. PMID:23128233

  10. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

    DEFF Research Database (Denmark)

    Jostins, Luke; Ripke, Stephan; Weersma, Rinse K

    2012-01-01

    Crohn's disease and ulcerative colitis, the two common forms of inflammatory bowel disease (IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other populations. Genome-wide association studies and subsequent meta-analyses of these two diseases as separate...... phenotypes have implicated previously unsuspected mechanisms, such as autophagy, in their pathogenesis and showed that some IBD loci are shared with other inflammatory diseases. Here we expand on the knowledge of relevant pathways by undertaking a meta-analysis of Crohn's disease and ulcerative colitis...

  11. Bifidobacterium breve - HT-29 cell line interaction: modulation of TNF-a induced gene expression

    NARCIS (Netherlands)

    Boesten, R.J.; Vos, de W.M.; Schuren, F.H.J.; Willemsen, L.E.M.; Knol, J.

    2011-01-01

    To provide insight in the molecular basis for intestinal host-microbe interactions, we determined the genome-wide transcriptional response of human intestinal epithelial cells following exposure to cells of Bifidobacterium breve. To select an appropriate test system reflecting inflammatory

  12. Bifidobacterium breve-HT-29 cell line interaction: Modulation of TNF-a induced gene expression

    NARCIS (Netherlands)

    Boesten, R.J.; Schuren, F.H.J.; Willemsen, L.E.M.; Vriesema, A.; Knol, J.; Vos, W.M. de

    2011-01-01

    To provide insight in the molecular basis for intestinal host-microbe interactions, we determined the genome-wide transcriptional response of human intestinal epithelial cells following exposure to cells of Bifidobacterium breve. To select an appropriate test system reflecting inflammatory

  13. A symbiosis-dedicated SYNTAXIN OF PLANTS 13II isoform controls the formation of a stable host-microbe interface in symbiosis.

    Science.gov (United States)

    Huisman, Rik; Hontelez, Jan; Mysore, Kirankumar S; Wen, Jiangqi; Bisseling, Ton; Limpens, Erik

    2016-09-01

    Arbuscular mycorrhizal (AM) fungi and rhizobium bacteria are accommodated in specialized membrane compartments that form a host-microbe interface. To better understand how these interfaces are made, we studied the regulation of exocytosis during interface formation. We used a phylogenetic approach to identify target soluble N-ethylmaleimide-sensitive factor-attachment protein receptors (t-SNAREs) that are dedicated to symbiosis and used cell-specific expression analysis together with protein localization to identify t-SNAREs that are present on the host-microbe interface in Medicago truncatula. We investigated the role of these t-SNAREs during the formation of a host-microbe interface. We showed that multiple syntaxins are present on the peri-arbuscular membrane. From these, we identified SYNTAXIN OF PLANTS 13II (SYP13II) as a t-SNARE that is essential for the formation of a stable symbiotic interface in both AM and rhizobium symbiosis. In most dicot plants, the SYP13II transcript is alternatively spliced, resulting in two isoforms, SYP13IIα and SYP13IIβ. These splice-forms differentially mark functional and degrading arbuscule branches. Our results show that vesicle traffic to the symbiotic interface is specialized and required for its maintenance. Alternative splicing of SYP13II allows plants to replace a t-SNARE involved in traffic to the plasma membrane with a t-SNARE that is more stringent in its localization to functional arbuscules. © 2016 The Authors. New Phytologist © 2016 New Phytologist Trust.

  14. The Role of Cell Surface Architecture of Lactobacilli in Host-Microbe Interactions in the Gastrointestinal Tract

    Directory of Open Access Journals (Sweden)

    Ranjita Sengupta

    2013-01-01

    Full Text Available Lactobacillus species can exert health promoting effects in the gastrointestinal tract (GIT through many mechanisms, which include pathogen inhibition, maintenance of microbial balance, immunomodulation, and enhancement of the epithelial barrier function. Different species of the genus Lactobacillus can evoke different responses in the host, and not all strains of the same species can be considered beneficial. Strain variations may be related to diversity of the cell surface architecture of lactobacilli and the bacteria's ability to express certain surface components or secrete specific compounds in response to the host environment. Lactobacilli are known to modify their surface structures in response to stress factors such as bile and low pH, and these adaptations may help their survival in the face of harsh environmental conditions encountered in the GIT. In recent years, multiple cell surface-associated molecules have been implicated in the adherence of lactobacilli to the GIT lining, immunomodulation, and protective effects on intestinal epithelial barrier function. Identification of the relevant bacterial ligands and their host receptors is imperative for a better understanding of the mechanisms through which lactobacilli exert their beneficial effects on human health.

  15. The role of gut microbiota in health and disease : In vitro modeling of host-microbe interactions at the aerobe-anaerobe interphase of the human gut

    NARCIS (Netherlands)

    von Martels, Julius Z. H.; Sadabad, Mehdi Sadaghian; Bourgonje, Arno R.; Blokzijl, Tjasso; Dijkstra, Gerard; Faber, Klaas Nico; Harmsen, Hermie J. M.

    The microbiota of the gut has many crucial functions in human health. Dysbiosis of the microbiota has been correlated to a large and still increasing number of diseases. Recent studies have mostly focused on analyzing the associations between disease and an aberrant microbiota composition.

  16. Genetic Transformation of an Obligate Anaerobe, P. gingivalis for FMN-Green Fluorescent Protein Expression in Studying Host-Microbe Interaction

    OpenAIRE

    Choi, Chul Hee; DeGuzman, Jefferson V.; Lamont, Richard J.; Yilmaz, Özlem

    2011-01-01

    The recent introduction of "oxygen-independent" flavin mononucleotide (FMN)-based fluorescent proteins (FbFPs) is of major interest to both eukaryotic and prokaryotic microbial biologists. Accordingly, we demonstrate for the first time that an obligate anaerobe, the successful opportunistic pathogen of the oral cavity, Porphyromonas gingivalis, can be genetically engineered for expression of the non-toxic green FbFP. The resulting transformants are functional for studying dynamic bacterial pr...

  17. Interactions between Drosophila and its natural yeast symbionts-Is Saccharomyces cerevisiae a good model for studying the fly-yeast relationship?

    Science.gov (United States)

    Hoang, Don; Kopp, Artyom; Chandler, James Angus

    2015-01-01

    Yeasts play an important role in the biology of the fruit fly, Drosophila melanogaster. In addition to being a valuable source of nutrition, yeasts affect D. melanogaster behavior and interact with the host immune system. Most experiments investigating the role of yeasts in D. melanogaster biology use the baker's yeast, Saccharomyces cerevisiae. However, S. cerevisiae is rarely found with natural populations of D. melanogaster or other Drosophila species. Moreover, the strain of S. cerevisiae used most often in D. melanogaster experiments is a commercially and industrially important strain that, to the best of our knowledge, was not isolated from flies. Since disrupting natural host-microbe interactions can have profound effects on host biology, the results from D. melanogaster-S. cerevisiae laboratory experiments may not be fully representative of host-microbe interactions in nature. In this study, we explore the D. melanogaster-yeast relationship using five different strains of yeast that were isolated from wild Drosophila populations. Ingested live yeasts have variable persistence in the D. melanogaster gastrointestinal tract. For example, Hanseniaspora occidentalis persists relative to S. cerevisiae, while Brettanomyces naardenensis is removed. Despite these differences in persistence relative to S. cerevisiae, we find that all yeasts decrease in total abundance over time. Reactive oxygen species (ROS) are an important component of the D. melanogaster anti-microbial response and can inhibit S. cerevisiae growth in the intestine. To determine if sensitivity to ROS explains the differences in yeast persistence, we measured yeast growth in the presence and absence of hydrogen peroxide. We find that B. naardenesis is completely inhibited by hydrogen peroxide, while H. occidentalis is not, which is consistent with yeast sensitivity to ROS affecting persistence within the D. melanogaster gastrointestinal tract. We also compared the feeding preference of D

  18. Interactive Dynamic-System Simulation

    CERN Document Server

    Korn, Granino A

    2010-01-01

    Showing you how to use personal computers for modeling and simulation, Interactive Dynamic-System Simulation, Second Edition provides a practical tutorial on interactive dynamic-system modeling and simulation. It discusses how to effectively simulate dynamical systems, such as aerospace vehicles, power plants, chemical processes, control systems, and physiological systems. Written by a pioneer in simulation, the book introduces dynamic-system models and explains how software for solving differential equations works. After demonstrating real simulation programs with simple examples, the author

  19. Wired to the roots: impact of root-beneficial microbe interactions on aboveground plant physiology and protection.

    Science.gov (United States)

    Kumar, Amutha Sampath; Bais, Harsh P

    2012-12-01

    Often, plant-pathogenic microbe interactions are discussed in a host-microbe two-component system, however very little is known about how the diversity of rhizospheric microbes that associate with plants affect host performance against pathogens. There are various studies, which specially direct the importance of induced systemic defense (ISR) response in plants interacting with beneficial rhizobacteria, yet we don't know how rhizobacterial associations modulate plant physiology. In here, we highlight the many dimensions within which plant roots associate with beneficial microbes by regulating aboveground physiology. We review approaches to study the causes and consequences of plant root association with beneficial microbes on aboveground plant-pathogen interactions. The review provides the foundations for future investigations into the impact of the root beneficial microbial associations on plant performance and innate defense responses.

  20. System dynamics with interaction discontinuity

    CERN Document Server

    Luo, Albert C J

    2015-01-01

    This book describes system dynamics with discontinuity caused by system interactions and presents the theory of flow singularity and switchability at the boundary in discontinuous dynamical systems. Based on such a theory, the authors address dynamics and motion mechanism of engineering discontinuous systems due to interaction. Stability and bifurcations of fixed points in nonlinear discrete dynamical systems are presented, and mapping dynamics are developed for analytical predictions of periodic motions in engineering discontinuous dynamical systems. Ultimately, the book provides an alternative way to discuss the periodic and chaotic behaviors in discontinuous dynamical systems.

  1. Natural interaction for unmanned systems

    Science.gov (United States)

    Taylor, Glenn; Purman, Ben; Schermerhorn, Paul; Garcia-Sampedro, Guillermo; Lanting, Matt; Quist, Michael; Kawatsu, Chris

    2015-05-01

    Military unmanned systems today are typically controlled by two methods: tele-operation or menu-based, search-andclick interfaces. Both approaches require the operator's constant vigilance: tele-operation requires constant input to drive the vehicle inch by inch; a menu-based interface requires eyes on the screen in order to search through alternatives and select the right menu item. In both cases, operators spend most of their time and attention driving and minding the unmanned systems rather than on being a warfighter. With these approaches, the platform and interface become more of a burden than a benefit. The availability of inexpensive sensor systems in products such as Microsoft Kinect™ or Nintendo Wii™ has resulted in new ways of interacting with computing systems, but new sensors alone are not enough. Developing useful and usable human-system interfaces requires understanding users and interaction in context: not just what new sensors afford in terms of interaction, but how users want to interact with these systems, for what purpose, and how sensors might enable those interactions. Additionally, the system needs to reliably make sense of the user's inputs in context, translate that interpretation into commands for the unmanned system, and give feedback to the user. In this paper, we describe an example natural interface for unmanned systems, called the Smart Interaction Device (SID), which enables natural two-way interaction with unmanned systems including the use of speech, sketch, and gestures. We present a few example applications SID to different types of unmanned systems and different kinds of interactions.

  2. A simple coculture system shows mutualism between anaerobic faecalibacteria and epithelial Caco-2 cells.

    Science.gov (United States)

    Sadaghian Sadabad, Mehdi; von Martels, Julius Z H; Khan, Muhammed Tanweer; Blokzijl, Tjasso; Paglia, Giuseppe; Dijkstra, Gerard; Harmsen, Hermie J M; Faber, Klaas Nico

    2015-12-15

    Most gut bacteria are obligate anaerobes and are important for human health. However, little mechanistic insight is available on the health benefits of specific anaerobic gut bacteria. A main obstacle in generating such knowledge is the lack of simple and robust coculturing methods for anaerobic bacteria and oxygen-requiring human cells. Here, we describe the development of a coculture system for intestinal Caco-2 cells and an anaerobic symbiont, Faecalibacterium prausnitzii, making use of 50 mL culture tubes. F. prausnitzii was grown in 40 mL YCFAG-agar with glass-adhered Caco-2 cells placed on top in 10 mL DMEM medium. Grown for 18-36 h in a humidified incubator at 37 °C and 5% CO2, coverslip-attached Caco-2 cells promoted growth and metabolism of F. prausnitzii, while F. prausnitzii suppressed inflammation and oxidative stress in Caco-2 cells. F. prausnitzii did not compromise Caco-2 cell viability. Exogenously added porcine mucin also promoted growth of F. prausnitzii, suggesting that it may be part of the mechanism of Caco-2-stimulated growth of F. prausnitzii. This 'Human oxygen-Bacteria anaerobic' (HoxBan) coculturing system uniquely establishes host-microbe mutualism of a beneficial anaerobic gut microbe in vitro and principally allows the analysis of host-microbe interactions of pure and mixed cultures of bacteria and human cells.

  3. Interactive Simulations of Biohybrid Systems

    Directory of Open Access Journals (Sweden)

    Sebastian Albrecht von Mammen

    2017-10-01

    Full Text Available In this article, we present approaches to interactive simulations of biohybrid systems. These simulations are comprised of two major computational components: (1 agent-based developmental models that retrace organismal growth and unfolding of technical scaffoldings and (2 interfaces to explore these models interactively. Simulations of biohybrid systems allow us to fast forward and experience their evolution over time based on our design decisions involving the choice, configuration and initial states of the deployed biological and robotic actors as well as their interplay with the environment. We briefly introduce the concept of swarm grammars, an agent-based extension of L-systems for retracing growth processes and structural artifacts. Next, we review an early augmented reality prototype for designing and projecting biohybrid system simulations into real space. In addition to models that retrace plant behaviors, we specify swarm grammar agents to braid structures in a self-organizing manner. Based on this model, both robotic and plant-driven braiding processes can be experienced and explored in virtual worlds. We present an according user interface for use in virtual reality. As we present interactive models concerning rather diverse description levels, we only ensured their principal capacity for interaction but did not consider efficiency analyzes beyond prototypic operation. We conclude this article with an outlook on future works on melding reality and virtuality to drive the design and deployment of biohybrid systems.

  4. The interactive surrogate travel system.

    Science.gov (United States)

    Nakajima, I; Ichimura, A; Juzoji, H; Mugita, K

    1999-01-01

    The Interactive Surrogate Travel (IST) system is based on the super-miniaturized system of virtual technology, Cave Automatic Virtual Environment (CAVE). Using bilateral virtual reality (VR-to-VR) communications, IST enables the testing of subjects via interactive communications. It appears that IST will find practical applications in the near future. We examined the utility of IST in medical treatment and psychiatric tests. Psychiatric symptoms reflect human pathos, which in turn are greatly influenced by culture. If these culture-bound symptoms can be adequately communicated between providers and clients of different cultures, we can develop effective telepsychiatric services across different societies and cultures. IST requires high-speed transmission and gigabyte circuits. A pilot project tested the utility of IST (through the use of optical fiber communications on earth) as a basis for experiments via the Gigabit satellite, to be launched in the year 2002.

  5. A Visual Formalism for Interacting Systems

    Directory of Open Access Journals (Sweden)

    Paul C. Jorgensen

    2015-04-01

    Full Text Available Interacting systems are increasingly common. Many examples pervade our everyday lives: automobiles, aircraft, defense systems, telephone switching systems, financial systems, national governments, and so on. Closer to computer science, embedded systems and Systems of Systems are further examples of interacting systems. Common to all of these is that some "whole" is made up of constituent parts, and these parts interact with each other. By design, these interactions are intentional, but it is the unintended interactions that are problematic. The Systems of Systems literature uses the terms "constituent systems" and "constituents" to refer to systems that interact with each other. That practice is followed here. This paper presents a visual formalism, Swim Lane Event-Driven Petri Nets, that is proposed as a basis for Model-Based Testing (MBT of interacting systems. In the absence of available tools, this model can only support the offline form of Model-Based Testing.

  6. Interacting particle systems on graphs

    Science.gov (United States)

    Sood, Vishal

    In this dissertation, the dynamics of socially or biologically interacting populations are investigated. The individual members of the population are treated as particles that interact via links on a social or biological network represented as a graph. The effect of the structure of the graph on the properties of the interacting particle system is studied using statistical physics techniques. In the first chapter, the central concepts of graph theory and social and biological networks are presented. Next, interacting particle systems that are drawn from physics, mathematics and biology are discussed in the second chapter. In the third chapter, the random walk on a graph is studied. The mean time for a random walk to traverse between two arbitrary sites of a random graph is evaluated. Using an effective medium approximation it is found that the mean first-passage time between pairs of sites, as well as all moments of this first-passage time, are insensitive to the density of links in the graph. The inverse of the mean-first passage time varies non-monotonically with the density of links near the percolation transition of the random graph. Much of the behavior can be understood by simple heuristic arguments. Evolutionary dynamics, by which mutants overspread an otherwise uniform population on heterogeneous graphs, are studied in the fourth chapter. Such a process underlies' epidemic propagation, emergence of fads, social cooperation or invasion of an ecological niche by a new species. The first part of this chapter is devoted to neutral dynamics, in which the mutant genotype does not have a selective advantage over the resident genotype. The time to extinction of one of the two genotypes is derived. In the second part of this chapter, selective advantage or fitness is introduced such that the mutant genotype has a higher birth rate or a lower death rate. This selective advantage leads to a dynamical competition in which selection dominates for large populations

  7. Quantifying Quality Aspects of Multimodal Interactive Systems

    CERN Document Server

    Kühnel, Christine

    2012-01-01

    This book systematically addresses the quantification of quality aspects of multimodal interactive systems. The conceptual structure is based on a schematic view on human-computer interaction where the user interacts with the system and perceives it via input and output interfaces. Thus, aspects of multimodal interaction are analyzed first, followed by a discussion of the evaluation of output and input and concluding with a view on the evaluation of a complete system.

  8. Systems interaction and single failure criterion

    International Nuclear Information System (INIS)

    1983-10-01

    This study is a continued assessment of US research. All three of the systems interaction review methodologies which NRC's Systems Interaction Section (SIS) is studying are recommended. They are the Digraph-Matrix Analysis and Interactive Fault Tree/Failure Modes and Effects Analysis methodologies. A third methodology was developed for the Indian Point 3 system interaction review. It is recommended to developing the capability to perform and evaluate systems interaction reviews at Swedish nuclear plants. The Swedish demonstration studies should be performed on BWR's. (G.B.)

  9. Narrative Cognition in Interactive Systems

    DEFF Research Database (Denmark)

    Bruni, Luis Emilio; Baceviciute, Sarune; Arief, Mohammed

    2014-01-01

    In this article we explore some of the methodological problems related to characterizing cognitive aspects of involvement with interactive narratives using well known EEG/ERP techniques. To exemplify this, we construct an experimental EEG-ERP set-up with an interactive narrative that considers th...

  10. Vehicle systems: coupled and interactive dynamics analysis

    Science.gov (United States)

    Vantsevich, Vladimir V.

    2014-11-01

    This article formulates a new direction in vehicle dynamics, described as coupled and interactive vehicle system dynamics. Formalised procedures and analysis of case studies are presented. An analytical consideration, which explains the physics of coupled system dynamics and its consequences for dynamics of a vehicle, is given for several sets of systems including: (i) driveline and suspension of a 6×6 truck, (ii) a brake mechanism and a limited slip differential of a drive axle and (iii) a 4×4 vehicle steering system and driveline system. The article introduces a formal procedure to turn coupled system dynamics into interactive dynamics of systems. A new research direction in interactive dynamics of an active steering and a hybrid-electric power transmitting unit is presented and analysed to control power distribution between the drive axles of a 4×4 vehicle. A control strategy integrates energy efficiency and lateral dynamics by decoupling dynamics of the two systems thus forming their interactive dynamics.

  11. Interacting Winds in Eclipsing Symbiotic Systems

    Indian Academy of Sciences (India)

    2016-01-27

    Jan 27, 2016 ... Interacting Winds in Eclipsing Symbiotic Systems – The Case Study of EG Andromedae ... to obtain the physical parameters of a quiescent eclipsing symbiotic system. ... Articles are also visible in Web of Science immediately.

  12. A Runtime System for Interactive Web Services

    DEFF Research Database (Denmark)

    Brabrand, Claus; Møller, Anders; Sandholm, Anders

    1999-01-01

    Interactive web services are increasingly replacing traditional static web pages. Producing web services seems to require a tremendous amount of laborious low-level coding due to the primitive nature of CGI programming. We present ideas for an improved runtime system for interactive web services...... built on top of CGI running on virtually every combination of browser and HTTP/CGI server. The runtime system has been implemented and used extensively in , a tool for producing interactive web services....

  13. Electron-electron interactions in disordered systems

    CERN Document Server

    Efros, AL

    1985-01-01

    ``Electron-Electron Interactions in Disordered Systems'' deals with the interplay of disorder and the Coulomb interaction. Prominent experts give state-of-the-art reviews of the theoretical and experimental work in this field and make it clear that the interplay of the two effects is essential, especially in low-dimensional systems.

  14. Vehicle/Guideway Interaction in Maglev Systems

    Science.gov (United States)

    1992-03-01

    Technology Division Materials and Components in Maglev Systems Technology Division Materials and Components Technology Division byY. Cai, S. S. Chen, and D. M...Transportation Systems Reports (UC-330, Vehicle/Guideway Interaction in Maglev Systems by Y. Cai and S. S. Chen Materials and Components Technology Division D. M...Surface Irregularities ...................................... 32 4 Vehicle/Guideway Interaction in Transrapid Maglev System .................. 34 4.1

  15. Using Interaction Scenarios to Model Information Systems

    DEFF Research Database (Denmark)

    Bækgaard, Lars; Bøgh Andersen, Peter

    The purpose of this paper is to define and discuss a set of interaction primitives that can be used to model the dynamics of socio-technical activity systems, including information systems, in a way that emphasizes structural aspects of the interaction that occurs in such systems. The primitives...... a number of case studies that indicate that interaction primitives can be useful modeling tools for supplementing conventional flow-oriented modeling of business processes....... are based on a unifying, conceptual definition of the disparate interaction types - a robust model of the types. The primitives can be combined and may thus represent mediated interaction. We present a set of visualizations that can be used to define multiple related interactions and we present and discuss...

  16. Automated Interactive Storeroom Inventory System.

    Science.gov (United States)

    Sapp, Albert L.; Hess, Larry G.

    1989-01-01

    The inventory system designed for six storerooms in three buildings at the University of Illinois at Urbana-Champaign's School of Chemical Sciences replaced an issue-slip and transactions record system with barcode technology. Data collection error reductions have been significant, making it easier to determine stock levels and plan purchases.…

  17. Predictive Systems for Customer Interactions

    Science.gov (United States)

    Vijayaraghavan, Ravi; Albert, Sam; Singh, Vinod Kumar; Kannan, Pallipuram V.

    With the coming of age of web as a mainstream customer service channel, B2C companies have invested substantial resources in enhancing their web presence. Today customers can interact with a company, not only through the traditional phone channel but also through chat, email, SMS or web self-service. Each of these channels is best suited for some services and ill-matched for others. Customer service organizations today struggle with the challenge of delivering seamlessly integrated services through these different channels. This paper will evaluate some of the key challenges in multi-channel customer service. It will address the challenge of creating the right channel mix i.e. providing the right choice of channels for a given customer/behavior/issue profile. It will also provide strategies for optimizing the performance of a given channel in creating the right customer experience.

  18. Semantic models for adaptive interactive systems

    CERN Document Server

    Hussein, Tim; Lukosch, Stephan; Ziegler, Jürgen; Calvary, Gaëlle

    2013-01-01

    Providing insights into methodologies for designing adaptive systems based on semantic data, and introducing semantic models that can be used for building interactive systems, this book showcases many of the applications made possible by the use of semantic models.Ontologies may enhance the functional coverage of an interactive system as well as its visualization and interaction capabilities in various ways. Semantic models can also contribute to bridging gaps; for example, between user models, context-aware interfaces, and model-driven UI generation. There is considerable potential for using

  19. A Runtime System for Interactive Web Services

    DEFF Research Database (Denmark)

    Brabrand, Claus; Møller, Anders; Sandholm, Anders

    1999-01-01

    Interactive web services are increasingly replacing traditional static web pages. Producing web services seems to require a tremendous amount of laborious low-level coding due to the primitive nature of CGI programming. We present ideas for an improved runtime system for interactive web services ...... built on top of CGI running on virtually every combination of browser and HTTP/CGI server. The runtime system has been implemented and used extensively in , a tool for producing interactive web services.......Interactive web services are increasingly replacing traditional static web pages. Producing web services seems to require a tremendous amount of laborious low-level coding due to the primitive nature of CGI programming. We present ideas for an improved runtime system for interactive web services...

  20. New Interactions with Workflow Systems

    NARCIS (Netherlands)

    Wassink, I.; van der Vet, P.E.; van der Veer, Gerrit C.; Roos, M.; van Dijk, Elisabeth M.A.G.; Norros, L.; Koskinen, H.; Salo, L.; Savioja, P.

    2009-01-01

    This paper describes the evaluation of our early design ideas of an ad-hoc of workflow system. Using the teach-back technique, we have performed a hermeneutic analysis of the mockup implementation named NIWS to get corrective and creative feedback at the functional, dialogue and representation level

  1. Network Physiology: How Organ Systems Dynamically Interact.

    Science.gov (United States)

    Bartsch, Ronny P; Liu, Kang K L; Bashan, Amir; Ivanov, Plamen Ch

    2015-01-01

    We systematically study how diverse physiologic systems in the human organism dynamically interact and collectively behave to produce distinct physiologic states and functions. This is a fundamental question in the new interdisciplinary field of Network Physiology, and has not been previously explored. Introducing the novel concept of Time Delay Stability (TDS), we develop a computational approach to identify and quantify networks of physiologic interactions from long-term continuous, multi-channel physiological recordings. We also develop a physiologically-motivated visualization framework to map networks of dynamical organ interactions to graphical objects encoded with information about the coupling strength of network links quantified using the TDS measure. Applying a system-wide integrative approach, we identify distinct patterns in the network structure of organ interactions, as well as the frequency bands through which these interactions are mediated. We establish first maps representing physiologic organ network interactions and discover basic rules underlying the complex hierarchical reorganization in physiologic networks with transitions across physiologic states. Our findings demonstrate a direct association between network topology and physiologic function, and provide new insights into understanding how health and distinct physiologic states emerge from networked interactions among nonlinear multi-component complex systems. The presented here investigations are initial steps in building a first atlas of dynamic interactions among organ systems.

  2. Network Physiology: How Organ Systems Dynamically Interact

    Science.gov (United States)

    Bartsch, Ronny P.; Liu, Kang K. L.; Bashan, Amir; Ivanov, Plamen Ch.

    2015-01-01

    We systematically study how diverse physiologic systems in the human organism dynamically interact and collectively behave to produce distinct physiologic states and functions. This is a fundamental question in the new interdisciplinary field of Network Physiology, and has not been previously explored. Introducing the novel concept of Time Delay Stability (TDS), we develop a computational approach to identify and quantify networks of physiologic interactions from long-term continuous, multi-channel physiological recordings. We also develop a physiologically-motivated visualization framework to map networks of dynamical organ interactions to graphical objects encoded with information about the coupling strength of network links quantified using the TDS measure. Applying a system-wide integrative approach, we identify distinct patterns in the network structure of organ interactions, as well as the frequency bands through which these interactions are mediated. We establish first maps representing physiologic organ network interactions and discover basic rules underlying the complex hierarchical reorganization in physiologic networks with transitions across physiologic states. Our findings demonstrate a direct association between network topology and physiologic function, and provide new insights into understanding how health and distinct physiologic states emerge from networked interactions among nonlinear multi-component complex systems. The presented here investigations are initial steps in building a first atlas of dynamic interactions among organ systems. PMID:26555073

  3. The interaction between the political system and the media system

    DEFF Research Database (Denmark)

    Almlund, Pernille

    The paper addresses how the media system and the political system in Denmark interact or couple. The overall question of the paper is whether this interaction should be seen as a strong and continuing structural coupling or as a new emerging system with a new binary code. The paper will be limited...

  4. Hydrodynamic limit of interacting particle systems

    International Nuclear Information System (INIS)

    Landim, C.

    2004-01-01

    We present in these notes two methods to derive the hydrodynamic equation of conservative interacting particle systems. The intention is to present the main ideas in the simplest possible context and refer for details and references. (author)

  5. Interaction effects in magnetic oxide nanoparticle systems

    Indian Academy of Sciences (India)

    The interaction effects in magnetic nanoparticle system were studied through a Monte Carlo simulation. The results of simulations were compared with two different magnetic systems, namely, iron oxide polymer nanocomposites prepared by polymerization over core and nanocrystalline cobalt ferrite thin films prepared by ...

  6. Some thoughts on interacting binary systems

    International Nuclear Information System (INIS)

    Ulrich, R.K.

    1980-01-01

    The author presents some thoughts on the theory and observation of interacting binary systems. The complex physical processes possible in these systems make our present understanding inconclusive. New types of observation (X-ray, EUV, radio) present new challenges to the theoretician. The author discusses those problems which seem to hold the most promise for future progress. (Auth.)

  7. Designing Networked Adaptive Interactive Hybrid Systems

    NARCIS (Netherlands)

    Kester, L.J.H.M.

    2008-01-01

    Advances in network technologies enable distributed systems, operating in complex physical environments, to coordinate their activities over larger areas within shorter time intervals. In these systems humans and intelligent machines will, in close interaction, be able to reach their goals under

  8. Identification of invariant measures of interacting systems

    International Nuclear Information System (INIS)

    Chen Jinwen

    2004-01-01

    In this paper we provide an approach for identifying certain mixture representations of some invariant measures of interacting stochastic systems. This is related to the problem of ergodicity of certain extremal invariant measures that are translation invariant. Corresponding to these, results concerning the existence of invariant measures and certain weak convergence of the systems are also provided

  9. Narrative Intelligibility and Closure in Interactive Systems

    DEFF Research Database (Denmark)

    Bruni, Luis Emilio; Baceviciute, Sarune

    2013-01-01

    In this article we define various aspects, or parameters, of interactive narrative systems and present them as a framework that can help authors, creators and designers to conceive, analyze, or prioritize the narrative goals of a given system. We start by defining the Author-Audience distance (AA...

  10. Interaction between classical and quantum systems

    International Nuclear Information System (INIS)

    Sherry, T.N.; Sudarshan, E.C.G.

    1977-10-01

    An unconventional approach to the measurement problem in quantum mechanics is considered--the apparatus is treated as a classical system, belonging to the macro-world. In order to have a measurement the apparatus must interact with the quantum system. As a first step, the classical apparatus is embedded into a large quantum mechanical structure, making use of a superselection principle. The apparatus and system are coupled such that the apparatus remains classical (principle of integrity), and unambiguous information of the values of a quantum observable are transferred to the variables of the apparatus. Further measurement of the classical apparatus can be done, causing no problems of principle. Thus interactions causing pointers to move (which are not treated) can be added. The restrictions placed by the principle of integrity on the form of the interaction between classical and quantum systems are examined and illustration is given by means of a simple example in which one sees the principle of integrity at work

  11. Realistic effective interactions for nuclear systems

    International Nuclear Information System (INIS)

    Hjort-Jensen, M.; Osnes, E.; Kuo, T.T.S.

    1994-09-01

    A review of perturbative many-body descriptions of several nuclear systems is presented. Symmetric and asymmetric nuclear matter and finite nuclei with few valence particles are examples of systems considered. The many-body description starts with the most recent meson-exchange potential models for the nucleon-nucleon interaction, an interaction which in turn is used in perturbative schemes to evaluate the effective interaction for finite nuclei and infinite nuclear matter. A unified perturbative approach based on time-dependent perturbation theory is elaborated. For finite nuclei new results are presented for the effective interaction and the energy spectra in the mass areas of oxygen, calcium and tin. 166 refs., 83 refs., 21 tabs

  12. The Human-Robot Interaction Operating System

    Science.gov (United States)

    Fong, Terrence; Kunz, Clayton; Hiatt, Laura M.; Bugajska, Magda

    2006-01-01

    In order for humans and robots to work effectively together, they need to be able to converse about abilities, goals and achievements. Thus, we are developing an interaction infrastructure called the "Human-Robot Interaction Operating System" (HRI/OS). The HRI/OS provides a structured software framework for building human-robot teams, supports a variety of user interfaces, enables humans and robots to engage in task-oriented dialogue, and facilitates integration of robots through an extensible API.

  13. The interactive evolution of human communication systems.

    Science.gov (United States)

    Fay, Nicolas; Garrod, Simon; Roberts, Leo; Swoboda, Nik

    2010-04-01

    This paper compares two explanations of the process by which human communication systems evolve: iterated learning and social collaboration. It then reports an experiment testing the social collaboration account. Participants engaged in a graphical communication task either as a member of a community, where they interacted with seven different partners drawn from the same pool, or as a member of an isolated pair, where they interacted with the same partner across the same number of games. Participants' horizontal, pair-wise interactions led "bottom up" to the creation of an effective and efficient shared sign system in the community condition. Furthermore, the community-evolved sign systems were as effective and efficient as the local sign systems developed by isolated pairs. Finally, and as predicted by a social collaboration account, and not by an iterated learning account, interaction was critical to the creation of shared sign systems, with different isolated pairs establishing different local sign systems and different communities establishing different global sign systems. Copyright © 2010 Cognitive Science Society, Inc.

  14. Repeated interactions in open quantum systems

    Energy Technology Data Exchange (ETDEWEB)

    Bruneau, Laurent, E-mail: laurent.bruneau@u-cergy.fr [Laboratoire AGM, Université de Cergy-Pontoise, Site Saint-Martin, BP 222, 95302 Cergy-Pontoise (France); Joye, Alain, E-mail: Alain.Joye@ujf-grenoble.fr [Institut Fourier, UMR 5582, CNRS-Université Grenoble I, BP 74, 38402 Saint-Martin d’Hères (France); Merkli, Marco, E-mail: merkli@mun.ca [Department of Mathematics and Statistics Memorial University of Newfoundland, St. John' s, NL Canada A1C 5S7 (Canada)

    2014-07-15

    Analyzing the dynamics of open quantum systems has a long history in mathematics and physics. Depending on the system at hand, basic physical phenomena that one would like to explain are, for example, convergence to equilibrium, the dynamics of quantum coherences (decoherence) and quantum correlations (entanglement), or the emergence of heat and particle fluxes in non-equilibrium situations. From the mathematical physics perspective, one of the main challenges is to derive the irreversible dynamics of the open system, starting from a unitary dynamics of the system and its environment. The repeated interactions systems considered in these notes are models of non-equilibrium quantum statistical mechanics. They are relevant in quantum optics, and more generally, serve as a relatively well treatable approximation of a more difficult quantum dynamics. In particular, the repeated interaction models allow to determine the large time (stationary) asymptotics of quantum systems out of equilibrium.

  15. Modeling of interaction effects in granular systems

    International Nuclear Information System (INIS)

    El-Hilo, M.; Shatnawy, M.; Al-Rsheed, A.

    2000-01-01

    Interaction effects on the magnetic behavior of granular solid systems are examined using a numerical model which is capable of predicting the field, temperature and time dependence of magnetization. In this work, interaction effects on the temperature dependence of time viscosity coefficient S(T) and formation of minor hysteresis loops have been studied. The results for the time- and temperature dependence of remanence ratio have showed that the distribution of energy barriers f(ΔE) obtained depend critically on the strength and nature of interactions. These interactions-based changes in f(ΔE) can easily give a temperature-independent behavior of S(T) when these changes give a 1/ΔE behavior to the distribution of energy barriers. Thus, conclusions about macroscopic quantum tunneling must be carefully drawn when the temperature dependence of S(T) is used to probe for MQT effects. For minor hysteresis effects, the result shows that for the non-interacting case, no minor hysteresis loops occur and the loops are only predicted when the interaction field is positive. From these predictions, minor loops will form when the interaction field is strong enough to magnetize some moments during the recoil process back to zero field. Thus, these minor loops are originated from interaction driving irreversible changes along the recoil curve and the irreversible component of magnetization has no direct influence on the formation of these minor loops

  16. Medical Information Management System (MIMS): A generalized interactive information system

    Science.gov (United States)

    Alterescu, S.; Friedman, C. A.; Hipkins, K. R.

    1975-01-01

    An interactive information system is described. It is a general purpose, free format system which offers immediate assistance where manipulation of large data bases is required. The medical area is a prime area of application. Examples of the system's operation, commentary on the examples, and a complete listing of the system program are included.

  17. Improved Interactive Medical-Imaging System

    Science.gov (United States)

    Ross, Muriel D.; Twombly, Ian A.; Senger, Steven

    2003-01-01

    An improved computational-simulation system for interactive medical imaging has been invented. The system displays high-resolution, three-dimensional-appearing images of anatomical objects based on data acquired by such techniques as computed tomography (CT) and magnetic-resonance imaging (MRI). The system enables users to manipulate the data to obtain a variety of views for example, to display cross sections in specified planes or to rotate images about specified axes. Relative to prior such systems, this system offers enhanced capabilities for synthesizing images of surgical cuts and for collaboration by users at multiple, remote computing sites.

  18. Systems interaction and single failure criterion

    International Nuclear Information System (INIS)

    1981-01-01

    This report documents the results of a six-month study to evaluate the ongoing research programs of the U.S. Nuclear Regulatory Commission (NRC) and U.S. commercial nuclear station owners which address the safety significance of systems interaction and the regulatory adequacy of the single failure criterion. The evaluation of system interactions provided is the initial phase of a more detailed study leading to the development and application of methodology for quantifying the relative safety of operating nuclear plants. (Auth.)

  19. Mood Swings: An Affective Interactive Art System

    Science.gov (United States)

    Bialoskorski, Leticia S. S.; Westerink, Joyce H. D. M.; van den Broek, Egon L.

    The progress in the field of affective computing enables the realization of affective consumer products, affective games, and affective art. This paper describes the affective interactive art system Mood Swings, which interprets and visualizes affect expressed by a person. Mood Swings is founded on the integration of a framework for affective movements and a color model. This enables Mood Swings to recognize affective movement characteristics as expressed by a person and display a color that matches the expressed emotion. With that, a unique interactive system is introduced, which can be considered as art, a game, or a combination of both.

  20. Magnetoelastic interaction in rare earth systems

    International Nuclear Information System (INIS)

    Dohm, V.

    1975-01-01

    A theory of rotationally invariant spin-lattice interactions in rare earth systems is presented. It is shown that rotational invariance to leading order is ensured only if rotational interactions of first and second order in the displacements are included simultaneously in the spin-lattice Hamiltonian. The rotational second-order interactions yield effects which are as large as those of the linear rotational interaction. It is pointed out that a corresponding statement should hold also for pure strain interactions. The phonon Green's function is calculated for the paramagnetic phase of rare earth systems. It is found that in an applied magnetic field the rotational interactions cause measureable changes of the phonon dispersion and the sound velocity even for cubic symmetry. These effects turn out to be of the same order of magnitude as the conventional field-dependent strain effects and are qualitatively different from the latter. The results of our theory are illustrated by the example of SmSb, and quantitative predictions for the transverse sound velocities are given. (orig.) [de

  1. Digraph matrix analysis applications to systems interactions

    International Nuclear Information System (INIS)

    Alesso, H.P.; Altenbach, T.; Lappa, D.; Kimura, C.; Sacks, I.J.; Ashmore, B.C.; Fromme, D.; Smith, C.F.; Williams, W.

    1984-01-01

    Complex events such as Three Mile Island-2, Brown's Ferry-3 and Crystal River-3 have demonstrated that previously unidentified system interdependencies can be important to safety. A major aspect of these events was dependent faults (common cause/mode failures). The term systems interactions has been introduced by the Nuclear Regulatory Commission (NRC) to identify the concepts of spatial and functional coupling of systems which can lead to system interdependencies. Spatial coupling refers to dependencies resulting from a shared environmental condition; functional coupling refers to both dependencies resulting from components shared between safety and/or support systems, and to dependencies involving human actions. The NRC is currently developing guidelines to search for and evaluate adverse systems interactions at light water reactors. One approach utilizes graph theoretical methods and is called digraph matrix analysis (DMA). This methodology has been specifically tuned to the systems interaction problem. The objective of this paper is to present results from two DMA applications and to contrast them with the results from more traditional fault tree approaches

  2. DECOUPLER DESIGN FOR AN INTERACTING TANKS SYSTEM

    Directory of Open Access Journals (Sweden)

    Duraid F. Ahmed

    2013-05-01

    Full Text Available The mathematical model forthe two interacting tanks system was derived and the dynamic behavior of thissystem was studied by introducing a step change in inlet flow rate. In thispaper, the analysis of the interaction loops between the controlled variable(liquid level and manipulated variable (inlet flow rate was carried out usingthe relative gain array. Also decoupling technique is applied to eliminate theeffect this interaction by design suitable decouplers for the system. Theresults show that the gain of each loop is cut in half when the opposite loopis closed and the gain of other loop changes sign when the opposite loop isclosed. The decoupling method show that the liquid level of tank one isconstant when the second inlet flow changes and to keep the liquid level oftank two constant the first inlet flow must be changed.

  3. A tabletop interactive storytelling system: designing for social interaction

    NARCIS (Netherlands)

    Alofs, Thijs; Theune, Mariet; Swartjes, I.M.T.

    This paper presents the Interactive Storyteller, a multi-user interface for AI-based interactive storytelling, where stories emerge from the interaction of human players with intelligent characters in a simulated story world. To support face-to-face contact and social interaction, we position users

  4. Extended sequence diagram for human system interaction

    International Nuclear Information System (INIS)

    Hwang, Jong Rok; Choi, Sun Woo; Ko, Hee Ran; Kim, Jong Hyun

    2012-01-01

    Unified Modeling Language (UML) is a modeling language in the field of object oriented software engineering. The sequence diagram is a kind of interaction diagram that shows how processes operate with one another and in what order. It is a construct of a message sequence chart. It depicts the objects and classes involved in the scenario and the sequence of messages exchanged between the objects needed to carry out the functionality of the scenario. This paper proposes the Extended Sequence Diagram (ESD), which is capable of depicting human system interaction for nuclear power plants, as well as cognitive process of operators analysis. In the conventional sequence diagram, there is a limit to only identify the activities of human and systems interactions. The ESD is extended to describe operators' cognitive process in more detail. The ESD is expected to be used as a task analysis method for describing human system interaction. The ESD can also present key steps causing abnormal operations or failures and diverse human errors based on cognitive condition

  5. The Metronome of Symbiosis: Interactions Between Microbes and the Host Circadian Clock.

    Science.gov (United States)

    Heath-Heckman, Elizabeth A C

    2016-11-01

    The entrainment of circadian rhythms, physiological cycles with a period of about 24 h, is regulated by a variety of mechanisms, including nonvisual photoreception. While circadian rhythms have been shown to be integral to many processes in multicellular organisms, including immune regulation, the effect of circadian rhythms on symbiosis, or host-microbe interactions, has only recently begun to be studied. This review summarizes recent work in the interactions of both pathogenic and mutualistic associations with host and symbiont circadian rhythms, focusing specifically on three mutualistic systems in which this phenomenon has been best studied. One important theme taken from these studies is the fact that mutualisms are profoundly affected by the circadian rhythms of the host, but that the microbial symbionts in these associations can, in turn, manipulate host rhythms. The interplay between circadian rhythms and symbiosis is a promising new field with effects that should be kept in mind when designing future studies across biology. © The Author 2016. Published by Oxford University Press on behalf of the Society for Integrative and Comparative Biology. All rights reserved. For permissions please email: journals.permissions@oup.com.

  6. Modeling of interaction effects in granular systems

    CERN Document Server

    El-Hilo, M; Al-Rsheed, A

    2000-01-01

    Interaction effects on the magnetic behavior of granular solid systems are examined using a numerical model which is capable of predicting the field, temperature and time dependence of magnetization. In this work, interaction effects on the temperature dependence of time viscosity coefficient S(T) and formation of minor hysteresis loops have been studied. The results for the time- and temperature dependence of remanence ratio have showed that the distribution of energy barriers f(DELTA E) obtained depend critically on the strength and nature of interactions. These interactions-based changes in f(DELTA E) can easily give a temperature-independent behavior of S(T) when these changes give a 1/DELTA E behavior to the distribution of energy barriers. Thus, conclusions about macroscopic quantum tunneling must be carefully drawn when the temperature dependence of S(T) is used to probe for MQT effects. For minor hysteresis effects, the result shows that for the non-interacting case, no minor hysteresis loops occur an...

  7. An interactive beam position monitor system simulator

    International Nuclear Information System (INIS)

    Ryan, W.A.; Shea, T.J.

    1993-03-01

    A system simulator has been implemented to aid the development of the RHIC position monitor system. Based on the LabVIEW software package by National Instruments, this simulator allows engineers and technicians to interactively explore the parameter space of a system during the design phase. Adjustable parameters are divided into three categories: beam, pickup, and electronics. The simulator uses these parameters in simple formulas to produce results in both time-domain and frequencydomain. During the prototyping phase, these simulated results can be compared to test data acquired with the same software package. The RHIC position monitor system is presented as an example, but the software is applicable to several other systems as well

  8. Stress Effects on Multiple Memory System Interactions

    Science.gov (United States)

    Ness, Deborah; Calabrese, Pasquale

    2016-01-01

    Extensive behavioural, pharmacological, and neurological research reports stress effects on mammalian memory processes. While stress effects on memory quantity have been known for decades, the influence of stress on multiple memory systems and their distinct contributions to the learning process have only recently been described. In this paper, after summarizing the fundamental biological aspects of stress/emotional arousal and recapitulating functionally and anatomically distinct memory systems, we review recent animal and human studies exploring the effects of stress on multiple memory systems. Apart from discussing the interaction between distinct memory systems in stressful situations, we will also outline the fundamental role of the amygdala in mediating such stress effects. Additionally, based on the methods applied in the herein discussed studies, we will discuss how memory translates into behaviour. PMID:27034845

  9. Stress Effects on Multiple Memory System Interactions

    Directory of Open Access Journals (Sweden)

    Deborah Ness

    2016-01-01

    Full Text Available Extensive behavioural, pharmacological, and neurological research reports stress effects on mammalian memory processes. While stress effects on memory quantity have been known for decades, the influence of stress on multiple memory systems and their distinct contributions to the learning process have only recently been described. In this paper, after summarizing the fundamental biological aspects of stress/emotional arousal and recapitulating functionally and anatomically distinct memory systems, we review recent animal and human studies exploring the effects of stress on multiple memory systems. Apart from discussing the interaction between distinct memory systems in stressful situations, we will also outline the fundamental role of the amygdala in mediating such stress effects. Additionally, based on the methods applied in the herein discussed studies, we will discuss how memory translates into behaviour.

  10. Stress Effects on Multiple Memory System Interactions.

    Science.gov (United States)

    Ness, Deborah; Calabrese, Pasquale

    2016-01-01

    Extensive behavioural, pharmacological, and neurological research reports stress effects on mammalian memory processes. While stress effects on memory quantity have been known for decades, the influence of stress on multiple memory systems and their distinct contributions to the learning process have only recently been described. In this paper, after summarizing the fundamental biological aspects of stress/emotional arousal and recapitulating functionally and anatomically distinct memory systems, we review recent animal and human studies exploring the effects of stress on multiple memory systems. Apart from discussing the interaction between distinct memory systems in stressful situations, we will also outline the fundamental role of the amygdala in mediating such stress effects. Additionally, based on the methods applied in the herein discussed studies, we will discuss how memory translates into behaviour.

  11. Interactions in the early solar system

    International Nuclear Information System (INIS)

    Dormand, J.R.; Woolfson, M.M.

    1977-01-01

    The capture theory of the origin of the solar system predicts protoplanets formed in near coplanar elliptical orbits with fairly high eccentricities. A resisting medium, which would be a byproduct of the capture event, would serve to round-off the orbits in a time which is short compared to the age of the solar system. It is shown that such a medium would also give rise to differential rotations of the lines of apses of the early planetary orbits, leading to a high probability of close interactions or collisions between planets. The consequences of a collision between two planets are considered. It is found that the larger planet could, in some cases, be expelled from the solar system and that the fragments of the small planet could give rise to some of the terrestrial planets. Moreover, it is suggested that the Earth-Moon system could be formed as as result of the capture of a major satellite of one of the colliding planets by a large fragment of the other planet. Mars is also identified in the satellite system of the ejected planet. Various types of debris from the collision could have produced the asteroids, meteorites and comets. An alternative explanation, in terms of the original event, is also given for the comets. The hypothesis is examined that Pluto is a byproduct of the collision, reaching its present orbit by interactions with Neptune. It is shown that as a consequence of such an interaction, Triton could have been perturbed sufficiently to reverse an initially prograde orbital motion. The transfer of Pluto from the collision region to the vicinity of Neptune could have occurred through multiple planetary perturbation. The outer satellites of Jupiter and Saturn are discussed in relation to the proposition that they originated from the debris of asteroid collisions within the spheres of influence of those planets. (author)

  12. Finite temperature system of strongly interacting baryons

    International Nuclear Information System (INIS)

    Bowers, R.L.; Gleeson, A.M.; Pedigo, R.D.; Wheeler, J.W.

    1976-07-01

    A fully relativistic finite temperature many body theory is constructed and used to examine the bulk properties of a system of strongly interacting baryons. The strong interactions are described by a two parameter phenomenological model fit to a simple description of nuclear matter at T = 0. The zero temperature equation of state for such a system which has already been discussed in the literature was developed to give a realistic description of nuclear matter. The model presented here is the exact finite temperature extension of that model. The effect of the inclusion of baryon pairs for T greater than or equal to 2mc 2 /k is discussed in detail. The phase transition identified with nuclear matter vanishes for system temperatures in excess of T/sub C/ = 1.034 x 10 11 0 K. All values of epsilon (P,T) correspond to systems that are causal in the sense that the locally determined speed of sound never exceeds the speed of light

  13. Finite temperature system of strongly interacting baryons

    Energy Technology Data Exchange (ETDEWEB)

    Bowers, R.L.; Gleeson, A.M.; Pedigo, R.D.; Wheeler, J.W.

    1976-07-01

    A fully relativistic finite temperature many body theory is constructed and used to examine the bulk properties of a system of strongly interacting baryons. The strong interactions are described by a two parameter phenomenological model fit to a simple description of nuclear matter at T = 0. The zero temperature equation of state for such a system which has already been discussed in the literature was developed to give a realistic description of nuclear matter. The model presented here is the exact finite temperature extension of that model. The effect of the inclusion of baryon pairs for T greater than or equal to 2mc/sup 2//k is discussed in detail. The phase transition identified with nuclear matter vanishes for system temperatures in excess of T/sub C/ = 1.034 x 10/sup 11/ /sup 0/K. All values of epsilon (P,T) correspond to systems that are causal in the sense that the locally determined speed of sound never exceeds the speed of light.

  14. Interactive orbital proximity operations planning system

    Science.gov (United States)

    Grunwald, Arthur J.; Ellis, Stephen R.

    1990-01-01

    An interactive graphical planning system for on-site planning of proximity operations in the congested multispacecraft environment about the space station is presented. The system shows the astronaut a bird's eye perspective of the space station, the orbital plane, and the co-orbiting spacecraft. The system operates in two operational modes: (1) a viewpoint mode, in which the astronaut is able to move the viewpoint around in the orbital plane to range in on areas of interest; and (2) a trajectory design mode, in which the trajectory is planned. Trajectory design involves the composition of a set of waypoints which result in a fuel-optimal trajectory which satisfies all operational constraints, such as departure and arrival constraints, plume impingement constraints, and structural constraints. The main purpose of the system is to present the trajectory and the constraints in an easily interpretable graphical format. Through a graphical interactive process, the trajectory waypoints are edited until all operational constraints are satisfied. A series of experiments was conducted to evaluate the system. Eight airline pilots with no prior background in orbital mechanics participated in the experiments. Subject training included a stand-alone training session of about 6 hours duration, in which the subjects became familiar with orbital mechanics concepts and performed a series of exercises to familiarize themselves with the control and display features of the system. They then carried out a series of production runs in which 90 different trajectory design situations were randomly addressed. The purpose of these experiments was to investigate how the planning time, planning efforts, and fuel expenditures were affected by the planning difficulty. Some results of these experiments are presented.

  15. Many Body Structure of Strongly Interacting Systems

    CERN Document Server

    Arenhövel, Hartmuth; Drechsel, Dieter; Friedrich, Jörg; Kaiser, Karl-Heinz; Walcher, Thomas; Symposium on 20 Years of Physics at the Mainz Microtron MAMI

    2006-01-01

    This carefully edited proceedings volume provides an extensive review and analysis of the work carried out over the past 20 years at the Mainz Microtron (MAMI). This research centered around the application of Quantum Chromodynamics in the strictly nonperturbative regime at hadronic scales of about 1 fm. Due to the many degrees of freedom in hadrons at this scale the leitmotiv of this research is "Many body structure of strongly interacting systems". Further, an outlook on the research with the forthcoming upgrade of MAMI is given. This volume is an authoritative source of reference for everyone interested in the field of the electro-weak probing of the structure of hadrons.

  16. Diffusion in Deterministic Interacting Lattice Systems

    Science.gov (United States)

    Medenjak, Marko; Klobas, Katja; Prosen, Tomaž

    2017-09-01

    We study reversible deterministic dynamics of classical charged particles on a lattice with hard-core interaction. It is rigorously shown that the system exhibits three types of transport phenomena, ranging from ballistic, through diffusive to insulating. By obtaining an exact expressions for the current time-autocorrelation function we are able to calculate the linear response transport coefficients, such as the diffusion constant and the Drude weight. Additionally, we calculate the long-time charge profile after an inhomogeneous quench and obtain diffusive profilewith the Green-Kubo diffusion constant. Exact analytical results are corroborated by Monte Carlo simulations.

  17. Genesis of dwarf galaxies in interacting system

    International Nuclear Information System (INIS)

    Duc, Pierre-Alain

    1995-01-01

    This research thesis addresses the study of interacting and merging galaxies, and more particularly the associated stellar formation episodes. The author first reports an analysis of the central regions of these objects by studying a specific class among them, i.e. galaxies discovered by the IRAS satellite which are ultra-luminous in the far infrared. The author presents results obtained by optical and infrared imagery and spectroscopy of a complete sample of objects located in the southern hemisphere. In the second part, the author focusses on outside regions of interacting galaxies, discusses the observation of filaments formed under the influence of tidal forces acting during galactic collisions, and of condensations which are as luminous as dwarf galaxies. Then a multi-wavelength study of several neighbouring systems revealed the existence of a specific class of objects, the tidal dwarf galaxies, which are formed from stellar and gaseous material snatched from the disk of interacting galaxies. Gas-rich tidal dwarf galaxies contain, like dwarf irregular galaxies or blue compact galaxies, newly formed stars. But, in opposition with these ones, they are richer in heavy elements: this is one of the consequences of a specific mode of galactic formation based on a cosmic recycling [fr

  18. Homeostasis between gut-associated microorganisms and the immune system in Drosophila.

    Science.gov (United States)

    You, Hyejin; Lee, Won Jun; Lee, Won-Jae

    2014-10-01

    The metabolic activities of a given gut bacterium or gut commensal community fluctuate in a manner largely depending on the physicochemical parameters within the gut niche. Recognition of the bacterial metabolic status in situ, by a sensing of the gut metabolites as a signature of a specific bacterial metabolic activity, has been suggested to be a highly beneficial means for the host to maintain gut-microbe homeostasis. Recently, analysis of Drosophila gut immunity revealed that bacterial-derived uracil and uracil-modulated intestinal reactive oxygen species (ROS) generation play a pivotal role in diverse aspects of host-microbe interactions, such as pathogen clearance, commensal protection, intestinal cell regeneration, colitogenesis, and possibly also interorgan immunological communication. A deeper understanding of the role of uracil in Drosophila immunity will provide additional insight into the molecular mechanisms underlying host-microbe symbiosis and dysbiosis. Copyright © 2014 Elsevier Ltd. All rights reserved.

  19. Interactive computer-enhanced remote viewing system

    International Nuclear Information System (INIS)

    Tourtellott, J.A.; Wagner, J.F.

    1995-01-01

    Remediation activities such as decontamination and decommissioning (D ampersand D) typically involve materials and activities hazardous to humans. Robots are an attractive way to conduct such remediation, but for efficiency they need a good three-dimensional (3-D) computer model of the task space where they are to function. This model can be created from engineering plans and architectural drawings and from empirical data gathered by various sensors at the site. The model is used to plan robotic tasks and verify that selected paths are clear of obstacles. This report describes the development of an Interactive Computer-Enhanced Remote Viewing System (ICERVS), a software system to provide a reliable geometric description of a robotic task space, and enable robotic remediation to be conducted more effectively and more economically

  20. Interactive computer-enhanced remote viewing system

    Energy Technology Data Exchange (ETDEWEB)

    Tourtellott, J.A.; Wagner, J.F. [Mechanical Technology Incorporated, Latham, NY (United States)

    1995-10-01

    Remediation activities such as decontamination and decommissioning (D&D) typically involve materials and activities hazardous to humans. Robots are an attractive way to conduct such remediation, but for efficiency they need a good three-dimensional (3-D) computer model of the task space where they are to function. This model can be created from engineering plans and architectural drawings and from empirical data gathered by various sensors at the site. The model is used to plan robotic tasks and verify that selected paths are clear of obstacles. This report describes the development of an Interactive Computer-Enhanced Remote Viewing System (ICERVS), a software system to provide a reliable geometric description of a robotic task space, and enable robotic remediation to be conducted more effectively and more economically.

  1. Interactive computer-enhanced remote viewing system

    International Nuclear Information System (INIS)

    Tourtellott, J.A.; Wagner, J.F.

    1995-01-01

    Remediation activities such as decontamination and decommissioning (D ampersand D) typically involve materials and activities hazardous to humans. Robots are an attractive way to conduct such remediation, but for efficiency they need a good three-dimensional (3-D) computer model of the task space where they are to function. This model can be created from engineering plans and architectural drawings and from empirical data gathered by various sensors at the site. The model is used to plan robotic tasks and verify that selected paths am clear of obstacles. This need for a task space model is most pronounced in the remediation of obsolete production facilities and underground storage tanks. Production facilities at many sites contain compact process machinery and systems that were used to produce weapons grade material. For many such systems, a complex maze of pipes (with potentially dangerous contents) must be removed, and this represents a significant D ampersand D challenge. In an analogous way, the underground storage tanks at sites such as Hanford represent a challenge because of their limited entry and the tumbled profusion of in-tank hardware. In response to this need, the Interactive Computer-Enhanced Remote Viewing System (ICERVS) is being designed as a software system to: (1) Provide a reliable geometric description of a robotic task space, and (2) Enable robotic remediation to be conducted more effectively and more economically than with available techniques. A system such as ICERVS is needed because of the problems discussed below

  2. Electron-phonon interactions in correlated systems

    International Nuclear Information System (INIS)

    Wysokinski, K.I.

    1996-01-01

    There exist attempts to describe the superconducting mechanism operating in HTS as based on antiferromagnetic fluctuations. It is not our intention to dwell on the superconducting mechanism, even though this is very a important issue. The main aim is to discuss the problem of interplay between electron-phonon and electron-electron interactions in correlated systems. We believe such analysis can be of importance for various materials and not only HTS'S. We shall however mainly refer to experiments on this last class of superconductors. Severe complications are to be expected by studying the problem. As is well known electron correlations are very important in narrow band systems, where the relevant electronic scale E F is quite small. In those circumstances, the phonon energy scale ω D is of comparable magnitude, with the ratio ω D /E F of order 1 signalling a possible break down of the Migdal - Eliashberg description of the electron-phonon interaction in metals. Here we shall assume the validity of the Migdal-Eliashberg approximation and concentrate on the mutual influence of electron and phonon subsystems. In the next section we shall discuss experimental motivation for and theoretical work related to the present problem. Section 3 contains a brief discussion of our theory. It is a self-consistent theory a la Migdal with strong correlations treated with an auxiliary boson technique. We conclude with results and their discussion. (orig.)

  3. Agent-based dynamic knowledge representation of Pseudomonas aeruginosa virulence activation in the stressed gut: Towards characterizing host-pathogen interactions in gut-derived sepsis.

    Science.gov (United States)

    Seal, John B; Alverdy, John C; Zaborina, Olga; An, Gary

    2011-09-19

    There is a growing realization that alterations in host-pathogen interactions (HPI) can generate disease phenotypes without pathogen invasion. The gut represents a prime region where such HPI can arise and manifest. Under normal conditions intestinal microbial communities maintain a stable, mutually beneficial ecosystem. However, host stress can lead to changes in environmental conditions that shift the nature of the host-microbe dialogue, resulting in escalation of virulence expression, immune activation and ultimately systemic disease. Effective modulation of these dynamics requires the ability to characterize the complexity of the HPI, and dynamic computational modeling can aid in this task. Agent-based modeling is a computational method that is suited to representing spatially diverse, dynamical systems. We propose that dynamic knowledge representation of gut HPI with agent-based modeling will aid in the investigation of the pathogenesis of gut-derived sepsis. An agent-based model (ABM) of virulence regulation in Pseudomonas aeruginosa was developed by translating bacterial and host cell sense-and-response mechanisms into behavioral rules for computational agents and integrated into a virtual environment representing the host-microbe interface in the gut. The resulting gut milieu ABM (GMABM) was used to: 1) investigate a potential clinically relevant laboratory experimental condition not yet developed--i.e. non-lethal transient segmental intestinal ischemia, 2) examine the sufficiency of existing hypotheses to explain experimental data--i.e. lethality in a model of major surgical insult and stress, and 3) produce behavior to potentially guide future experimental design--i.e. suggested sample points for a potential laboratory model of non-lethal transient intestinal ischemia. Furthermore, hypotheses were generated to explain certain discrepancies between the behaviors of the GMABM and biological experiments, and new investigatory avenues proposed to test those

  4. Agent-based dynamic knowledge representation of Pseudomonas aeruginosa virulence activation in the stressed gut: Towards characterizing host-pathogen interactions in gut-derived sepsis

    Directory of Open Access Journals (Sweden)

    Zaborina Olga

    2011-09-01

    Full Text Available Abstract Background There is a growing realization that alterations in host-pathogen interactions (HPI can generate disease phenotypes without pathogen invasion. The gut represents a prime region where such HPI can arise and manifest. Under normal conditions intestinal microbial communities maintain a stable, mutually beneficial ecosystem. However, host stress can lead to changes in environmental conditions that shift the nature of the host-microbe dialogue, resulting in escalation of virulence expression, immune activation and ultimately systemic disease. Effective modulation of these dynamics requires the ability to characterize the complexity of the HPI, and dynamic computational modeling can aid in this task. Agent-based modeling is a computational method that is suited to representing spatially diverse, dynamical systems. We propose that dynamic knowledge representation of gut HPI with agent-based modeling will aid in the investigation of the pathogenesis of gut-derived sepsis. Methodology/Principal Findings An agent-based model (ABM of virulence regulation in Pseudomonas aeruginosa was developed by translating bacterial and host cell sense-and-response mechanisms into behavioral rules for computational agents and integrated into a virtual environment representing the host-microbe interface in the gut. The resulting gut milieu ABM (GMABM was used to: 1 investigate a potential clinically relevant laboratory experimental condition not yet developed - i.e. non-lethal transient segmental intestinal ischemia, 2 examine the sufficiency of existing hypotheses to explain experimental data - i.e. lethality in a model of major surgical insult and stress, and 3 produce behavior to potentially guide future experimental design - i.e. suggested sample points for a potential laboratory model of non-lethal transient intestinal ischemia. Furthermore, hypotheses were generated to explain certain discrepancies between the behaviors of the GMABM and biological

  5. Transient Behaviour of Interacting Extractive System

    International Nuclear Information System (INIS)

    El-Bialy, S.H.; Elsherbiny, A.E.

    2000-01-01

    The aim of this study is to investigate the dynamic behaviour of mixer-settler extractive system, which represents an interacting one. When a stimulus single is introduced to aqueous feed; the response of the aqueous phase of the first stage is considered as stimulus signals to both organic phase in the same stage and the aqueous phase of the second one. The response of the last phase represents-in turn- stimulus signals to both organic phase in the same stage and the aqueous phase in the next one. Mathematical model was derived for a system consisting of two stages in the cascade. The model assumed a continuous stirred tank reactor (CSTR) for mixer zone and variable holdups and flow rates of both aqueous and organic phases during operation. Non-linear equilibrium was considered. The obtained model-being non-linear- was linearized and Laplace transformation method was used to solve the model. The system constants are those corresponding to extraction of uranyl nitrate from 3 N nitric acid solution using Tbp dissolved in kerosene at 30% of the former. Stimulus-response test was carried out on the model by considering a step increase in solute concentration in aqueous feed stream. The system behaviour was tested at different values of operating parameters. First order behaviour for the first stage was observed and higher order for the rest of the system. A general relation for the difference in the power of the denominator and numerator of the transfer function of the i th stage was concluded for aqueous phase. The study showed that the system overdamp over the practical range of chosen parameters as explained from the values of transfer function roots

  6. Interactive computer enhanced remote viewing system

    International Nuclear Information System (INIS)

    Smith, D.A.; Tourtellott, J.A.

    1994-01-01

    The Interactive, Computer Enhanced, Remote Viewing System (ICERVSA) is a volumetric data system designed to help the Department of Energy (DOE) improve remote operations in hazardous sites by providing reliable and accurate maps of task spaces where robots will clean up nuclear wastes. The ICERVS mission is to acquire, store, integrate and manage all the sensor data for a site and to provide the necessary tools to facilitate its visualization and interpretation. Empirical sensor data enters through the Common Interface for Sensors and after initial processing, is stored in the Volumetric Database. The data can be analyzed and displayed via a Graphic User Interface with a variety of visualization tools. Other tools permit the construction of geometric objects, such as wire frame models, to represent objects which the operator may recognize in the live TV image. A computer image can be generated that matches the viewpoint of the live TV camera at the remote site, facilitating access to site data. Lastly, the data can be gathered, processed, and transmitted in acceptable form to a robotic controller. Descriptions are given of all these components. The final phase of the ICERVS project, which has just begun, will produce a full scale system and demonstrate it at a DOE site to be selected. A task added to this Phase will adapt the ICERVS to meet the needs of the Dismantlement and Decommissioning (D and D) work at the Oak Ridge National Laboratory (ORNL)

  7. Mass loss from interacting close binary systems

    Science.gov (United States)

    Plavec, M. J.

    1981-01-01

    The three well-defined classes of evolved binary systems that show evidence of present and/or past mass loss are the cataclysmic variables, the Algols, and Wolf-Rayet stars. It is thought that the transformation of supergiant binary systems into the very short-period cataclysmic variables must have been a complex process. The new evidence that has recently been obtained from the far ultraviolet spectra that a certain subclass of the Algols (the Serpentids) are undergoing fairly rapid evolution is discussed. It is thought probable that the remarkable mass outflow observed in them is connected with a strong wind powered by accretion. The origin of the circumbinary clouds or flat disks that probably surround many strongly interacting binaries is not clear. Attention is also given to binary systems with hot white dwarf or subdwarf components, such as the symbiotic objects and the BQ stars; it is noted that in them both components may be prone to an enhanced stellar wind.

  8. Augmenting Environmental Interaction in Audio Feedback Systems

    Directory of Open Access Journals (Sweden)

    Seunghun Kim

    2016-04-01

    Full Text Available Audio feedback is defined as a positive feedback of acoustic signals where an audio input and output form a loop, and may be utilized artistically. This article presents new context-based controls over audio feedback, leading to the generation of desired sonic behaviors by enriching the influence of existing acoustic information such as room response and ambient noise. This ecological approach to audio feedback emphasizes mutual sonic interaction between signal processing and the acoustic environment. Mappings from analyses of the received signal to signal-processing parameters are designed to emphasize this specificity as an aesthetic goal. Our feedback system presents four types of mappings: approximate analyses of room reverberation to tempo-scale characteristics, ambient noise to amplitude and two different approximations of resonances to timbre. These mappings are validated computationally and evaluated experimentally in different acoustic conditions.

  9. IPLOT, interactive MELCOR data plotting system

    International Nuclear Information System (INIS)

    2008-01-01

    1 - Description of program or function: IPLOT is an interactive MELCOR data plotting system. It provides several kinds of GUI interfaces for a flexible data plotting. IPLOT capabilities include creation, saving and loading of user specified MELCOR variables trend graphs. IPLOT can use one or several plot files for a graph generation while the graphs can be either in one window or in several windows. Besides IPLOT provides several graph convenient functions such as zooming, re-sizing, printing for a detail analysis of severe accidents. 2 - Methods: Trend values seeking in a plot file is performed by a binary search method for fast performance. 3 - Restrictions on the complexity of the problem: MELCOR plot files are required for plotting

  10. Effective Coulomb interaction in multiorbital system

    International Nuclear Information System (INIS)

    Hase, Izumi; Yanagisawa, Takashi

    2013-01-01

    Transition metal atom generally takes various valences, and sometimes there are some 'missing valences', for example Fe usually takes 2+, 3+ and 5+, but does not take other valences so often. We have calculated the atomic multiplet energies for the high-spin and lowspin configurations within the ligand-field theory and the Hartree-Fock approximation, and found that the Coulomb interaction energy (U eff ) becomes small when the valence is 'missing'. In case U eff B /Fe only when U eff increased in most cases, but in some special cases U eff decreases and falls below the value U − 3J, which is the least value of the undistorted system.

  11. Fluid structure interaction in piping systems

    Energy Technology Data Exchange (ETDEWEB)

    Svingen, Bjoernar

    1996-12-31

    The Dr. ing. thesis relates to an analysis of fluid structure interaction in piping systems in the frequency domain. The governing equations are the water hammer equations for the liquid, and the beam-equations for the structure. The fluid and structural equations are coupled through axial stresses and fluid continuity relations controlled by the contraction factor (Poisson coupling), and continuity and force relations at the boundaries (junction coupling). A computer program has been developed using the finite element method as a discretization technique both for the fluid and for the structure. This is made for permitting analyses of large systems including branches and loops, as well as including hydraulic piping components, and experiments are executed. Excitations are made in a frequency range from zero Hz and up to at least one thousand Hz. Frequency dependent friction is modelled as stiffness proportional Rayleigh damping both for the fluid and for the structure. With respect to the water hammer equations, stiffness proportional damping is seen as an artificial (bulk) viscosity term. A physical interpretation of this term in relation to transient/oscillating hydraulic pipe-friction is given. 77 refs., 72 figs., 4 tabs.

  12. Design of a decentralized detection of interacting LTI systems

    Directory of Open Access Journals (Sweden)

    Shamanth Shankar

    2002-01-01

    Full Text Available In this paper, the problem of designing a decentralized detection filter for a large homogeneous collection of LTI systems is considered. The collection of systems considered here draws inspiration from platoons of vehicles, and the considered interactions amongst systems in the collection are banded and lower triangular, mimicking the typical “look-ahead” nature of interactions in a platoon of vehicles. A fault in a system propagates to other systems in the collection via such interactions.

  13. Continuous limit of discrete systems with long-range interaction

    International Nuclear Information System (INIS)

    Tarasov, Vasily E

    2006-01-01

    Discrete systems with long-range interactions are considered. Continuous medium models as continuous limit of discrete chain system are defined. Long-range interactions of chain elements that give the fractional equations for the medium model are discussed. The chain equations of motion with long-range interaction are mapped into the continuum equation with the Riesz fractional derivative. We formulate the consistent definition of continuous limit for the systems with long-range interactions. In this paper, we consider a wide class of long-range interactions that give fractional medium equations in the continuous limit. The power-law interaction is a special case of this class

  14. Transient bimodality in interacting particle systems

    International Nuclear Information System (INIS)

    Calderoni, P.; Pellegrinotti, A.; Presutti, E.; Vares, M.E.

    1989-01-01

    The authors consider a system of spins which have values ± 1 and evolve according to a jump Markov process whose generator is the sum of two generators, one describing a spin-flip Glauber process, the other a Kawasaki (stirring) evolution. It was proven elsewhere that if the Kawasaki dynamics is speeded up by a factor var-epsilon -2 , then, in the limit var-epsilon → 0 (continuum limit), propagation of chaos holds and the local magnetization solves a reaction-diffusion equation. They choose the parameters of the Glauber interaction so that the potential of the reaction term in the reaction-diffusion equation is a double-well potential with quartic maximum at the origin. They assume further that for each var-epsilon the system is in a finite interval of Z with var-epsilon -1 sites and periodic boundary conditions. They specify the initial measure as the product measure with 0 spin average, thus obtaining, in the continuum limit, a constant magnetic profile equal to 0, which is a stationary unstable solution to the reaction-diffusion equation. They prove that at times of the order var-epsilon -1/2 propagation of chaos does not hold any more and, in the limit as var-epsilon → 0, the state becomes a nontrivial superposition of Bernoulli measures with parameters corresponding to the minima of the reaction potential. The coefficients of such a superposition depend on time (on the scale var-epsilon -1/2 ) and at large times (on this scale) the coefficient of the term corresponding to the initial magnetization vanishes (transient bimodality). This differs from what was observed by De Masi, Presutti, and Vares, who considered a reaction potential with quadratic maximum and no bimodal effect was seen, as predicted by Broggi, Lugiato, and Colombo

  15. Selecting personnel to work on the interactive graphics system

    International Nuclear Information System (INIS)

    Norton, F.J.

    1979-01-01

    The paper established criteria for the selection of personnel to work on the interactive graphics system and mentions some of human behavioral patterns that are created by the implementation of graphic systems. Some of the social and educational problems associated with the interactive graphics system will be discussed. The project also provided for collecting objective data which would be useful in assessing the benefits of interactive graphics systems

  16. Selecting personnel to work on the interactive graphics system

    Energy Technology Data Exchange (ETDEWEB)

    Norton, F.J.

    1979-11-30

    The paper established criteria for the selection of personnel to work on the interactive graphics system and mentions some of human behavioral patterns that are created by the implementation of graphic systems. Some of the social and educational problems associated with the interactive graphics system will be discussed. The project also provided for collecting objective data which would be useful in assessing the benefits of interactive graphics systems.

  17. International Conference on Intelligent and Interactive Systems and Applications

    CERN Document Server

    Patnaik, Srikanta; Yu, Zhengtao

    2017-01-01

    This book provides the latest research findings and developments in the field of interactive intelligent systems, addressing diverse areas such as autonomous systems, Internet and cloud computing, pattern recognition and vision systems, mobile computing and intelligent networking, and e-enabled systems. It gathers selected papers from the International Conference on Intelligent and Interactive Systems and Applications (IISA2016) held on June 25–26, 2016 in Shanghai, China. Interactive intelligent systems are among the most important multi-disciplinary research and development domains of artificial intelligence, human–computer interaction, machine learning and new Internet-based technologies. Accordingly, these systems embrace a considerable number of application areas such as autonomous systems, expert systems, mobile systems, recommender systems, knowledge-based and semantic web-based systems, virtual communication environments, and decision support systems, to name a few. To date, research on interactiv...

  18. An Interactive Tool for Creating Multi-Agent Systems and Interactive Agent-based Games

    DEFF Research Database (Denmark)

    Lund, Henrik Hautop; Pagliarini, Luigi

    2011-01-01

    Utilizing principles from parallel and distributed processing combined with inspiration from modular robotics, we developed the modular interactive tiles. As an educational tool, the modular interactive tiles facilitate the learning of multi-agent systems and interactive agent-based games...

  19. Long-range interaction of anisotropic systems

    KAUST Repository

    Zhang, Junyi

    2015-02-01

    The first-order electrostatic interaction energy between two far-apart anisotropic atoms depends not only on the distance between them but also on their relative orientation, according to Rayleigh-Schrödinger perturbation theory. Using the first-order interaction energy and the continuum model, we study the long-range interaction between a pair of parallel pristine graphene sheets at zero temperature. The asymptotic form of the obtained potential density, &epsi:(D) &prop: ?D ?3 ?O(D?4), is consistent with the random phase approximation and Lifshitz theory. Accordingly, neglectance of the anisotropy, especially the nonzero first-order interaction energy, is the reason why the widely used Lennard-Jones potential approach and dispersion corrections in density functional theory give a wrong asymptotic form ε(D) &prop: ?D?4. © EPLA, 2015.

  20. Long-range interaction of anisotropic systems

    KAUST Repository

    Zhang, Junyi; Schwingenschlö gl, Udo

    2015-01-01

    The first-order electrostatic interaction energy between two far-apart anisotropic atoms depends not only on the distance between them but also on their relative orientation, according to Rayleigh-Schrödinger perturbation theory. Using the first-order interaction energy and the continuum model, we study the long-range interaction between a pair of parallel pristine graphene sheets at zero temperature. The asymptotic form of the obtained potential density, &epsi:(D) &prop: ?D ?3 ?O(D?4), is consistent with the random phase approximation and Lifshitz theory. Accordingly, neglectance of the anisotropy, especially the nonzero first-order interaction energy, is the reason why the widely used Lennard-Jones potential approach and dispersion corrections in density functional theory give a wrong asymptotic form ε(D) &prop: ?D?4. © EPLA, 2015.

  1. A Mobile Personal Informatics System with Interactive Visualizations of Mobility and Social Interactions

    DEFF Research Database (Denmark)

    Cuttone, Andrea; Jørgensen, Sune Lehmann; Larsen, Jakob Eg

    2013-01-01

    We describe a personal informatics system for Android smartphones that provides personal data on mobility and social interactions through interactive visualization interfaces. The mobile app has been made available to N=136 first year university students as part of a study of social network...... interactions in a university campus setting. The design of the interactive visualization interfaces enabling the participants to gain insights into own behaviors is described. We report initial findings based on device logging of participant interactions with the interactive visualization app on the smartphone...

  2. New players in the same old game: a system level in silico study to predict type III secretion system and effector proteins in bacterial genomes reveals common themes in T3SS mediated pathogenesis.

    Science.gov (United States)

    Sadarangani, Vineet; Datta, Sunando; Arunachalam, Manonmani

    2013-07-26

    Type III secretion system (T3SS) plays an important role in virulence or symbiosis of many pathogenic or symbiotic bacteria [CHM 2:291-294, 2007; Physiology (Bethesda) 20:326-339, 2005]. T3SS acts like a tunnel between a bacterium and its host through which the bacterium injects 'effector' proteins into the latter [Nature 444:567-573, 2006; COSB 18:258-266, 2008]. The effectors spatially and temporally modify the host signalling pathways [FEMS Microbiol Rev 35:1100-1125, 2011; Cell Host Microbe5:571-579, 2009]. In spite its crucial role in host-pathogen interaction, the study of T3SS and the associated effectors has been limited to a few bacteria [Cell Microbiol 13:1858-1869, 2011; Nat Rev Microbiol 6:11-16, 2008; Mol Microbiol 80:1420-1438, 2011]. Before one set out to perform systematic experimental studies on an unknown set of bacteria it would be beneficial to identify the potential candidates by developing an in silico screening algorithm. A system level study would also be advantageous over traditional laboratory methods to extract an overriding theme for host-pathogen interaction, if any, from the vast resources of data generated by sequencing multiple bacterial genomes. We have developed an in silico protocol in which the most conserved set of T3SS proteins was used as the query against the entire bacterial database with increasingly stringent search parameters. It enabled us to identify several uncharacterized T3SS positive bacteria. We adopted a similar strategy to predict the presence of the already known effectors in the newly identified T3SS positive bacteria. The huge resources of biochemical data [FEMS Microbiol Rev 35:1100-1125, 2011; Cell Host Microbe 5:571-579, 2009; BMC Bioinformatics 7(11):S4, 2010] on the T3SS effectors enabled us to search for the common theme in T3SS mediated pathogenesis. We identified few cellular signalling networks in the host, which are manipulated by most of the T3SS containing pathogens. We went on to look for

  3. A Hybrid Recommender System Based on User-Recommender Interaction

    OpenAIRE

    Zhang, Heng-Ru; Min, Fan; He, Xu; Xu, Yuan-Yuan

    2015-01-01

    Recommender systems are used to make recommendations about products, information, or services for users. Most existing recommender systems implicitly assume one particular type of user behavior. However, they seldom consider user-recommender interactive scenarios in real-world environments. In this paper, we propose a hybrid recommender system based on user-recommender interaction and evaluate its performance with recall and diversity metrics. First, we define the user-recommender interaction...

  4. An ontology for human-like interaction systems

    OpenAIRE

    Albacete García, Esperanza

    2016-01-01

    This report proposes and describes the development of a Ph.D. Thesis aimed at building an ontological knowledge model supporting Human-Like Interaction systems. The main function of such knowledge model in a human-like interaction system is to unify the representation of each concept, relating it to the appropriate terms, as well as to other concepts with which it shares semantic relations. When developing human-like interactive systems, the inclusion of an ontological module can be valuab...

  5. Cellular structures in a system of interacting particles

    International Nuclear Information System (INIS)

    Lev, B.I.

    2009-01-01

    The general description of the formation of a cellular structure in the system of interacting particles is proposed. The analytical results for possible cellular structures in the usual colloidal systems, systems of particles immersed in a liquid crystal, and gravitational systems have been presented. It is shown that the formation of a cellular structure in all systems of interacting particles at different temperatures and concentrations of particles has the same physical nature

  6. Digraph Matrix Analysis: A new approach to systems interaction analysis

    International Nuclear Information System (INIS)

    Sacks, I.J.; Alesso, H.P.; Ashmore, B.C.

    1985-01-01

    The term Systems Interaction was introduced by the Nuclear Regulatory Commission to identify interdependency of safety and support systems. Digraph Matrix Analysis was developed to allow the determination of these interdependencies. The main features of DMA are: the reliability model is traced directly from system schematics, all components of front line and support systems are included in a single integrated model, and the model is processed automatically with no heuristic culling applied. The recent application of DMA to the Indian Point-3 systems interaction analysis resulted in the discovery of several significant deeply hidden systems interactions

  7. Interactive Videos Enhance Learning about Socio-Ecological Systems

    Science.gov (United States)

    Smithwick, Erica; Baxter, Emily; Kim, Kyung; Edel-Malizia, Stephanie; Rocco, Stevie; Blackstock, Dean

    2018-01-01

    Two forms of interactive video were assessed in an online course focused on conservation. The hypothesis was that interactive video enhances student perceptions about learning and improves mental models of social-ecological systems. Results showed that students reported greater learning and attitudes toward the subject following interactive video.…

  8. Interactive Control System, Intended Strategy, Implemented Strategy dan Emergent Strategy

    Directory of Open Access Journals (Sweden)

    Tubagus Ismail

    2012-09-01

    Full Text Available The purpose of this study was to examine the relationship between management control system (MCS and strategy formation processes, namely: intended strategy, emergent strategy and impelemented strategy. The focus of MCS in this study was interactive control system. The study was based on Structural Equation Modeling (SEM as its multivariate analyses instrument. The samples were upper middle managers of manufacturing company in Banten Province, DKI Jakarta Province and West Java Province. AMOS Software 16 program is used as an additional instrument to resolve the problem in SEM modeling. The study found that interactive control system brought a positive and significant influence on Intended strategy; interactive control system brought a positive and significant influence on implemented strategy; interactive control system brought a positive and significant influence on emergent strategy. The limitation of this study is that our empirical model only used one way relationship between the process of strategy formation and interactive control system.

  9. Preferences in Interactive Systems: Technical Challenges and Case Studies

    OpenAIRE

    Peintner, Bart; Viappiani, Paolo; Yorke-Smith, Neil

    2008-01-01

    Interactive artificial intelligence systems employ preferences in both their reasoning and their interaction with the user. This survey considers preference handling in applications such as recommender systems, personal assistant agents, and personalized user interfaces. We survey the major questions and approaches, present illustrative examples, and give an outlook on potential benefits and challenges.

  10. Natural Interaction Based Online Military Boxing Learning System

    Science.gov (United States)

    Yang, Chenglei; Wang, Lu; Sun, Bing; Yin, Xu; Wang, Xiaoting; Liu, Li; Lu, Lin

    2013-01-01

    Military boxing, a kind of Chinese martial arts, is widespread and health beneficial. In this paper, the authors introduce a military boxing learning system realized by 3D motion capture, Web3D and 3D interactive technologies. The interactions with the system are natural and intuitive. Users can observe and learn the details of each action of the…

  11. User Interaction Modeling and Profile Extraction in Interactive Systems: A Groupware Application Case Study †

    Science.gov (United States)

    Tîrnăucă, Cristina; Duque, Rafael; Montaña, José L.

    2017-01-01

    A relevant goal in human–computer interaction is to produce applications that are easy to use and well-adjusted to their users’ needs. To address this problem it is important to know how users interact with the system. This work constitutes a methodological contribution capable of identifying the context of use in which users perform interactions with a groupware application (synchronous or asynchronous) and provides, using machine learning techniques, generative models of how users behave. Additionally, these models are transformed into a text that describes in natural language the main characteristics of the interaction of the users with the system. PMID:28726762

  12. An interactive videodisc system for training

    International Nuclear Information System (INIS)

    Cadwell, J.J.

    1987-01-01

    Under the sponsorship of the U.S. Department of Energy's Office of Classification (DOE/OC), Brookhaven National Laboratory/Technical Support Organization (BNL/TSO) has prepared a level-three interactive-laserdisc program for the training of authorized classifiers in the Department of Energy. This training programs consists of six modules presented in several formats. The material is presented in a highly interactive manner with various tests to reinforce and evaluate the trainee's progress in learning the material. A lengthy qualification test is presented at the end of the educational material. The various instructional techniques of scenario presentation, ''talking heads'', graphics, textual material and combinations of the above are used to assure that the training material attracts the trainee's interests and motivates him to understand and use the material. The state-of-the-art interactive laser videodisc with its storage capacity, speed flexibility, and superior training capacity was the logical choice for the training of Authorized Classifiers in the Department of Energy

  13. Modeling Users' Experiences with Interactive Systems

    CERN Document Server

    Karapanos, Evangelos

    2013-01-01

    Over the past decade the field of Human-Computer Interaction has evolved from the study of the usability of interactive products towards a more holistic understanding of how they may mediate desired human experiences.  This book identifies the notion of diversity in usersʼ experiences with interactive products and proposes methods and tools for modeling this along two levels: (a) interpersonal diversity in usersʽ responses to early conceptual designs, and (b) the dynamics of usersʼ experiences over time. The Repertory Grid Technique is proposed as an alternative to standardized psychometric scales for modeling interpersonal diversity in usersʼ responses to early concepts in the design process, and new Multi-Dimensional Scaling procedures are introduced for modeling such complex quantitative data. iScale, a tool for the retrospective assessment of usersʼ experiences over time is proposed as an alternative to longitudinal field studies, and a semi-automated technique for the analysis of the elicited exper...

  14. Preventing Illegitimate Teenage Pregnancy Through Systems Interaction

    Science.gov (United States)

    Jarvis, D. L.

    1971-01-01

    Social workers, Cooperating with doctors, nurses, hospital social workers and educators in other helping systems, conducted a demonstration project described here, aimed at preventing illegitimate teenage pregnancy. (Author)

  15. Towards Compensation Correctness in Interactive Systems

    Science.gov (United States)

    Vaz, Cátia; Ferreira, Carla

    One fundamental idea of service-oriented computing is that applications should be developed by composing already available services. Due to the long running nature of service interactions, a main challenge in service composition is ensuring correctness of failure recovery. In this paper, we use a process calculus suitable for modelling long running transactions with a recovery mechanism based on compensations. Within this setting, we discuss and formally state correctness criteria for compensable processes compositions, assuming that each process is correct with respect to failure recovery. Under our theory, we formally interpret self-healing compositions, that can detect and recover from failures, as correct compositions of compensable processes.

  16. Mobile gaze input system for pervasive interaction

    DEFF Research Database (Denmark)

    2017-01-01

    feedback to the user in response to the received command input. The unit provides feedback to the user on how to position the mobile unit in front of his eyes. The gaze tracking unit interacts with one or more controlled devices via wireless or wired communications. Example devices include a lock......, a thermostat, a light or a TV. The connection between the gaze tracking unit may be temporary or longer-lasting. The gaze tracking unit may detect features of the eye that provide information about the identity of the user....

  17. User interaction in modern web information systems

    NARCIS (Netherlands)

    Barna, P.; Houben, G.J.P.M.; De Bra, P.M.E.

    2003-01-01

    Modern Information Systems based on Web technologies (Web-based Information Systems - WIS) typically generate hypermedia presentations according to the user needs. Hera is our model-driven methodology specifying the design cycle and the architecture framework for WIS. To avoid additional expensive

  18. Energy exchange in systems of particles with nonreciprocal interaction

    Energy Technology Data Exchange (ETDEWEB)

    Vaulina, O. S.; Lisina, I. I., E-mail: Irina.Lisina@mail.ru; Lisin, E. A. [Russian Academy of Sciences, Joint Institute for High Temperatures (Russian Federation)

    2015-10-15

    A model is proposed to describe the sources of additional kinetic energy and its redistribution in systems of particles with a nonreciprocal interaction. The proposed model is shown to explain the qualitative specific features of the dust particle dynamics in the sheath region of an RF discharge. Prominence is given to the systems of particles with a quasi-dipole–dipole interaction, which is similar to the interaction induced by the ion focusing effects that occur in experiments on a laboratory dusty plasma, and with the shadow interaction caused by thermophoretic forces and Le Sage’s forces.

  19. Research and realization of key technology in HILS interactive system

    Science.gov (United States)

    Liu, Che; Lu, Huiming; Wang, Fankai

    2018-03-01

    This paper designed HILS (Hardware In the Loop Simulation) interactive system based on xPC platform . Through the interface between C++ and MATLAB engine, establish the seamless data connection between Simulink and interactive system, complete data interaction between system and Simulink, realize the function development of model configuration, parameter modification and off line simulation. We establish the data communication between host and target machine through TCP/IP protocol to realize the model download and real-time simulation. Use database to store simulation data, implement real-time simulation monitoring and simulation data management. Realize system function integration by Qt graphic interface library and dynamic link library. At last, take the typical control system as an example to verify the feasibility of HILS interactive system.

  20. An Online Interactive Competition Model for E-Learning System ...

    African Journals Online (AJOL)

    An Online Interactive Competition Model for E-Learning System. ... A working prototype of the system was developed using MySQL Database Management System (DBMS), PHP as the scripting language and Apache as the web server. The system was tested and the results were presented graphically in this paper.

  1. Interactive Russian Grammar: The Case System

    Directory of Open Access Journals (Sweden)

    Rimma Gam

    2009-01-01

    Full Text Available My paper addresses a problem many of us in North American college language programs confront regularly, the solution to which regularly and frustratingly remains just out of our reach. I refer to the teaching of the most basic and most crucial element of Russian grammar, namely, its case system, and teaching it to our students whose native language, English, does not have such a system. As I teach the Russian cases, I see vividly the disconnect between grammar presented for students (simplified, episodic, based on the "pick it up along the way" principle and the learned papers on Russian grammar by linguists, which are barely comprehensible to a non-linguist. Materials in the middle are lacking-materials to help a literature professor acting as a "de facto" language instructor understand and address the needs of students as they learn this crucial segment of basic Russian grammar. This core element of Russian grammar is presented to students in the first year of college language study, is revisited in the second year, and very often by the third year students either manage to completely block it out from their memory (as if it were some traumatic experience that happened "a long time ago"-that is, before .summer break-but most importantly due to the lack of practice or demonstrate a partial or even complete lack of understanding or misunderstanding of this system forcing us to deal with it again in the third year. Not only is it frustrating for both the students and the language instructor; but from the point of view of their overall proficiency, the lack of control of the case system holds our students back. There can be no talk of advanced language proficiency without a complete and automatic mastery of this basic system. Unfortunately, regardless of the specific textbooks used, the students very often manage not to have a general idea and mastery of this system even by the third year of study.

  2. Education in Accounting Using an Interactive System

    Directory of Open Access Journals (Sweden)

    Bogdan Patrut

    2010-04-01

    Full Text Available This paper represents a summary of a research report and the results of developing an educational software, including a multi-agent system for teaching accounting bases and financial accounting. The paper describes the structure of the multi-agent system, defined as a complex network of s-agents. Each s-agent contains 6 pedagogical agents and a coordinator agent. We havedefined a new architecture (BeSGOTE that extends the BDI architecture for intelligent agents and we have defined a mixing-up relation among the accounts, presenting the way in which it can be used for testing students.

  3. Phenylketonuria: central nervous system and microbiome interaction

    Directory of Open Access Journals (Sweden)

    Demian Arturo Herrera Morban

    2017-06-01

    Full Text Available Phenylketonuria (PKU is an autosomal recessive inborn error of metabolism characterized by increased phenylalanine (Phe levels causing an inadequate neurodevelopment; the treatment of PKU is a Phe-restricting diet, and as such it can modulate the intestinal microbiome of the individual, generating central nervous system secondary disturbances that, added to the baseline disturbance, can influence the outcome of the disease.

  4. Interactive data-processing system for metallurgy

    Science.gov (United States)

    Rathz, T. J.

    1978-01-01

    Equipment indicates that system can rapidly and accurately process metallurgical and materials-processing data for wide range of applications. Advantages include increase in contract between areas on image, ability to analyze images via operator-written programs, and space available for storing images.

  5. Interacting Brain Systems Modulate Memory Consolidation

    Science.gov (United States)

    McIntyre, Christa K.; McGaugh, James L.; Williams, Cedric L.

    2011-01-01

    Emotional arousal influences the consolidation of long-term memory. This review discusses experimental approaches and relevant findings that provide the foundation for current understanding of coordinated interactions between arousal activated peripheral hormones and the brain processes that modulate memory formation. Rewarding or aversive experiences release the stress hormones epinephrine (adrenalin) and glucocorticoids from the adrenal glands into the bloodstream. The effect of these hormones on memory consolidation depends upon binding of norepinephrine to beta-adrenergic receptors in the basolateral complex of the amygdala (BLA). Much evidence indicates that the stress hormones influence release of norepinephrine in the BLA through peripheral actions on the vagus nerve which stimulates, through polysynaptic connections, cells of the locus coeruleus to release norepinephrine. The BLA influences memory storage by actions on synapses, distributed throughout the brain, that are engaged in sensory and cognitive processing at the time of amygdala activation. The implications of the activation of these stress-activated memory processes are discussed in relation to stress-related memory disorders. PMID:22085800

  6. Internet-based Interactive Construction Management Learning System.

    Science.gov (United States)

    Sawhney, Anil; Mund, Andre; Koczenasz, Jeremy

    2001-01-01

    Describes a way to incorporate practical content into the construction engineering and management curricula: the Internet-based Interactive Construction Management Learning System, which uses interactive and adaptive learning environments to train students in the areas of construction methods, equipment and processes using multimedia, databases,…

  7. Fluctuations in interacting particle systems with memory

    International Nuclear Information System (INIS)

    Harris, Rosemary J

    2015-01-01

    We consider the effects of long-range temporal correlations in many-particle systems, focusing particularly on fluctuations about the typical behaviour. For a specific class of memory dependence we discuss the modification of the large deviation principle describing the probability of rare currents and show how superdiffusive behaviour can emerge. We illustrate the general framework with detailed calculations for a memory-dependent version of the totally asymmetric simple exclusion process as well as indicating connections to other recent work

  8. High Performance Interactive System Dynamics Visualization

    Energy Technology Data Exchange (ETDEWEB)

    Bush, Brian W [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Brunhart-Lupo, Nicholas J [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Gruchalla, Kenny M [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Duckworth, Jonathan C [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-09-14

    This brochure describes a system dynamics simulation (SD) framework that supports an end-to-end analysis workflow that is optimized for deployment on ESIF facilities(Peregrine and the Insight Center). It includes (I) parallel and distributed simulation of SD models, (ii) real-time 3D visualization of running simulations, and (iii) comprehensive database-oriented persistence of simulation metadata, inputs, and outputs.

  9. High Performance Interactive System Dynamics Visualization

    Energy Technology Data Exchange (ETDEWEB)

    Bush, Brian W [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Brunhart-Lupo, Nicholas J [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Gruchalla, Kenny M [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Duckworth, Jonathan C [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-09-14

    This presentation describes a system dynamics simulation (SD) framework that supports an end-to-end analysis workflow that is optimized for deployment on ESIF facilities(Peregrine and the Insight Center). It includes (I) parallel and distributed simulation of SD models, (ii) real-time 3D visualization of running simulations, and (iii) comprehensive database-oriented persistence of simulation metadata, inputs, and outputs.

  10. Stress Effects on Multiple Memory System Interactions

    OpenAIRE

    Ness, Deborah; Calabrese, Pasquale

    2016-01-01

    Extensive behavioural, pharmacological, and neurological research reports stress effects on mammalian memory processes. While stress effects on memory quantity have been known for decades, the influence of stress on multiple memory systems and their distinct contributions to the learning process have only recently been described. In this paper, after summarizing the fundamental biological aspects of stress/emotional arousal and recapitulating functionally and anatomically distinct memory syst...

  11. Conservative interacting particles system with anomalous rate of ergodicity

    OpenAIRE

    Brzeźniak, Zdzislaw; Flandoli, Franco; Neklyudov, Misha; Zegarliński, Boguslaw

    2010-01-01

    We analyze certain conservative interacting particle system and establish ergodicity of the system for a family of invariant measures. Furthermore, we show that convergence rate to equilibrium is exponential. This result is of interest because it presents counterexample to the standard assumption of physicists that conservative system implies polynomial rate of convergence.

  12. Interactive Model-Centric Systems Engineering (IMCSE) Phase 5

    Science.gov (United States)

    2018-02-28

    Interactive Model-Centric Systems Engineering (IMCSE) Phase 5 Technical Report SERC-2018-TR-104 Feb 28, 2018 Principal Investigator...Date February 28, 2018 Copyright © 2018 Stevens Institute of Technology, Systems Engineering ...Research Center The Systems Engineering Research Center (SERC) is a federally funded University Affiliated Research Center managed by Stevens

  13. Integrable Hamiltonian systems and interactions through quadratic constraints

    International Nuclear Information System (INIS)

    Pohlmeyer, K.

    1975-08-01

    Osub(n)-invariant classical relativistic field theories in one time and one space dimension with interactions that are entirely due to quadratic constraints are shown to be closely related to integrable Hamiltonian systems. (orig.) [de

  14. Orbit correction system for the SSC interaction regions

    International Nuclear Information System (INIS)

    Nosochkov, Y.; Pilat, F.; Ritson, D.M.

    1994-01-01

    In this paper we review our design of the orbit correction system for the SSC interaction regions, and discuss the principles of the local orbit correction at the IP. copyright 1994 American Institute of Physics

  15. Integrated multimedia information system on interactive CATV network

    Science.gov (United States)

    Lee, Meng-Huang; Chang, Shin-Hung

    1998-10-01

    In the current CATV system architectures, they provide one- way delivery of a common menu of entertainment to all the homes through the cable network. Through the technologies evolution, the interactive services (or two-way services) can be provided in the cable TV systems. They can supply customers with individualized programming and support real- time two-way communications. With a view to the service type changed from the one-way delivery systems to the two-way interactive systems, `on demand services' is a distinct feature of multimedia systems. In this paper, we present our work of building up an integrated multimedia system on interactive CATV network in Shih Chien University. Besides providing the traditional analog TV programming from the cable operator, we filter some channels to reserve them as our campus information channels. In addition to the analog broadcasting channel, the system also provides the interactive digital multimedia services, e.g. Video-On- Demand (VOD), Virtual Reality, BBS, World-Wide-Web, and Internet Radio Station. These two kinds of services are integrated in a CATV network by the separation of frequency allocation for the analog broadcasting service and the digital interactive services. Our ongoing work is to port our previous work of building up a VOD system conformed to DAVIC standard (for inter-operability concern) on Ethernet network into the current system.

  16. Final Report of Strongly Interacting Fermion Systems

    International Nuclear Information System (INIS)

    Wilkins, J. W.

    2001-01-01

    There has been significant progress in three broad areas: (A) Optical properties, (B) Large-scale computations, and (C) Many-body systems. In this summary the emphasis is primarily on those papers that point to the research plans. At the same time, some important analytic work is not neglected, some of it even appearing in the description of large-scale Computations. Indeed one of the aims of such computations is to give new insights which lead to development of models capable of simple analytic or nearly analytic analysis

  17. Properties of interacting low-dimensional systems

    CERN Document Server

    Gumbs, Godfrey

    2013-01-01

    Filling the gap for comprehensive coverage of the realistic fundamentals and approaches needed to perform cutting-edge research on mesoscopic systems, this textbook allows advanced students to acquire and use the skills at a highly technical, research-qualifying level. Starting with a brief refresher to get all readers on an equal footing, the text moves on to a broad selection of advanced topics, backed by problems with solutions for use in classrooms as well as for self-study. Written by authors with research and teaching backgrounds from eminent institutions and based on a tried-and

  18. Social interaction recruits mentalizing and reward systems in middle childhood.

    Science.gov (United States)

    Alkire, Diana; Levitas, Daniel; Warnell, Katherine Rice; Redcay, Elizabeth

    2018-06-08

    Social cognition develops in the context of reciprocal social interaction. However, most neuroimaging studies of mentalizing have used noninteractive tasks that may fail to capture important aspects of real-world mentalizing. In adults, social-interactive context modulates activity in regions linked to social cognition and reward, but few interactive studies have been done with children. The current fMRI study examines children aged 8-12 using a novel paradigm in which children believed they were interacting online with a peer. We compared mental and non-mental state reasoning about a live partner (Peer) versus a story character (Character), testing the effects of mentalizing and social interaction in a 2 × 2 design. Mental versus Non-Mental reasoning engaged regions identified in prior mentalizing studies, including the temporoparietal junction, superior temporal sulcus, and dorsomedial prefrontal cortex. Moreover, peer interaction, even in conditions without explicit mentalizing demands, activated many of the same mentalizing regions. Peer interaction also activated areas outside the traditional mentalizing network, including the reward system. Our results demonstrate that social interaction engages multiple neural systems during middle childhood and contribute further evidence that social-interactive paradigms are needed to fully capture how the brain supports social processing in the real world. © 2018 Wiley Periodicals, Inc.

  19. RKKY interaction in mixed valence system and heavy fermion superconductivity

    International Nuclear Information System (INIS)

    Fusui Liu; Gao Lin; Lin Zonghan

    1985-11-01

    The 1-D RKKY interaction of mixed valence system is given by using the thermodynamic perturbation theory. The numerical comparisons of 1-D and 3-D RKKY interaction between systems with localized magnetic moments of mixed valence and non-mixed valence show that the former is much stronger than the latter. From some analyses we propose that the heavy Fermion superconductivity comes from the RKKY interaction between two local f electrons which hop off the impurity site to become two continuum electrons. The source of the two impurity electrons hopping is the Coulomb interaction. It is also emphasized that the RKKY interaction does not disappear for the Kondo lattice, when the temperature is less than the Kondo temperature. (author)

  20. Dynamical system analysis of interacting models

    Science.gov (United States)

    Carneiro, S.; Borges, H. A.

    2018-01-01

    We perform a dynamical system analysis of a cosmological model with linear dependence between the vacuum density and the Hubble parameter, with constant-rate creation of dark matter. We show that the de Sitter spacetime is an asymptotically stable critical point, future limit of any expanding solution. Our analysis also shows that the Minkowski spacetime is an unstable critical point, which eventually collapses to a singularity. In this way, such a prescription for the vacuum decay not only predicts the correct future de Sitter limit, but also forbids the existence of a stable Minkowski universe. We also study the effect of matter creation on the growth of structures and their peculiar velocities, showing that it is inside the current errors of redshift space distortions observations.

  1. Phantom-based interactive simulation system for dental treatment training.

    Science.gov (United States)

    Sae-Kee, Bundit; Riener, Robert; Frey, Martin; Pröll, Thomas; Burgkart, Rainer

    2004-01-01

    In this paper, we propose a new interactive simulation system for dental treatment training. The system comprises a virtual reality environment and a force-torque measuring device to enhance the capabilities of a passive phantom of tooth anatomy in dental treatment training processes. The measuring device is connected to the phantom, and provides essential input data for generating the graphic animations of physical behaviors such as drilling and bleeding. The animation methods of those physical behaviors are also presented. This system is not only able to enhance interactivity and accessibility of the training system compared to conventional methods but it also provides possibilities of recording, evaluating, and verifying the training results.

  2. Interactive analysis of systems biology molecular expression data

    Directory of Open Access Journals (Sweden)

    Prabhakar Sunil

    2008-02-01

    Full Text Available Abstract Background Systems biology aims to understand biological systems on a comprehensive scale, such that the components that make up the whole are connected to one another and work through dependent interactions. Molecular correlations and comparative studies of molecular expression are crucial to establishing interdependent connections in systems biology. The existing software packages provide limited data mining capability. The user must first generate visualization data with a preferred data mining algorithm and then upload the resulting data into the visualization package for graphic visualization of molecular relations. Results Presented is a novel interactive visual data mining application, SysNet that provides an interactive environment for the analysis of high data volume molecular expression information of most any type from biological systems. It integrates interactive graphic visualization and statistical data mining into a single package. SysNet interactively presents intermolecular correlation information with circular and heatmap layouts. It is also applicable to comparative analysis of molecular expression data, such as time course data. Conclusion The SysNet program has been utilized to analyze elemental profile changes in response to an increasing concentration of iron (Fe in growth media (an ionomics dataset. This study case demonstrates that the SysNet software is an effective platform for interactive analysis of molecular expression information in systems biology.

  3. Assess program: Interactive data management systems for airborne research

    Science.gov (United States)

    Munoz, R. M.; Reller, J. O., Jr.

    1974-01-01

    Two data systems were developed for use in airborne research. Both have distributed intelligence and are programmed for interactive support among computers and with human operators. The C-141 system (ADAMS) performs flight planning and telescope control functions in addition to its primary role of data acquisition; the CV-990 system (ADDAS) performs data management functions in support of many research experiments operating concurrently. Each system is arranged for maximum reliability in the first priority function, precision data acquisition.

  4. Intersite interactions and susceptibility in mixed valence systems

    International Nuclear Information System (INIS)

    Xiaoqian Wang; Gao Lin; Bingjian Ni; Fusui Liu.

    1985-10-01

    This paper considers the effect of intersite processes on the susceptibility in mixed valence system. The method of thermodynamical perturbation used in this paper can also be generalized to study other properties of mixed valence system. The general formula of partition function of two-site interactions for the mixed valence system is given. The numerical calculations show that the intersite interaction is large enough to explain the minimum of susceptibility discovered in experiments. The different types of our theoretical curves predict that the susceptibility should exhibit a rich variety of behaviour at low temperature for various materials. (author)

  5. Towards a simulation of disordered systems with interactions

    International Nuclear Information System (INIS)

    MacKinnon, Angus

    2008-01-01

    We consider the problem of Anderson localization in disordered systems with interactions. We present a numerical approach in quasi-one-dimensional (quasi-1D) systems which combines aspects of the transfer matrix and Green's function recursion methods with the density matrix renormalization group. The method is applied to spinless fermions in 1D and a generalization to finite cross-sections is outlined

  6. A review of currently available high performance interactive graphics systems

    International Nuclear Information System (INIS)

    Clark, S.A.; Harvey, J.

    1981-12-01

    A survey of several interactive graphics systems is given, all but one of which being based on calligraphic technology, which are being considered for a new High Energy Physics graphics facility at RAL. A brief outline of the system architectures is given, the detailed features being summarised in an appendix, and their relative merits are discussed. (U.K.)

  7. A Complete Interactive Graphical Computer-Aided Instruction System.

    Science.gov (United States)

    Abrams, Steven Selby

    The use of interactive graphics in computer-aided instruction systems is discussed with emphasis placed on two requirements of such a system. The first is the need to provide the teacher with a useful tool with which to design and modify teaching sessions tailored to the individual needs and capabilities of the students. The second is the…

  8. Homogenization of a thermo-diffusion system with Smoluchowski interactions

    NARCIS (Netherlands)

    Krehel, O.; Aiki, T.; Muntean, A.

    2014-01-01

    We study the solvability and homogenization of a thermal-diffusion reaction problem posed in a periodically perforated domain. The system describes the motion of populations of hot colloidal particles interacting together via Smoluchowski production terms. The upscaled system, obtained via two-scale

  9. AUTOMATED COMPUTER SYSTEM FOR INTERACTIVE COMMUNICATION WITH А DRIVER

    Directory of Open Access Journals (Sweden)

    A. Kravchenko

    2012-01-01

    Full Text Available The electronic system which serves for the convenience of driving and improve neut of traffic safety has been regarded. Innovative development of an integrated system of voice control with the possibility of interactive communication and the function of preventing from falling asleep has been given.

  10. Analysis of pattern formation in systems with competing range interactions

    International Nuclear Information System (INIS)

    Zhao, H J; Misko, V R; Peeters, F M

    2012-01-01

    We analyzed pattern formation and identified various morphologies in a system of particles interacting through a non-monotonic potential with a competing range interaction characterized by a repulsive core (r c ) and an attractive tail (r > r c ), using molecular-dynamics simulations. Depending on parameters, the interaction potential models the inter-particle interaction in various physical systems ranging from atoms, molecules and colloids to vortices in low κ type-II superconductors and in recently discovered ‘type-1.5’ superconductors. We constructed a ‘morphology diagram’ in the plane ‘critical radius r c -density n’ and proposed a new approach to characterizing the different types of patterns. Namely, we elaborated a set of quantitative criteria in order to identify the different pattern types, using the radial distribution function (RDF), the local density function and the occupation factor. (paper)

  11. Some aspects of the interaction between systems- and structural reliability

    International Nuclear Information System (INIS)

    Schueller, G.K.; Schmitt, W.

    1979-01-01

    The purpose of this paper is to study the interaction between systems- and structural reliability analysis with reference to the design of structural components of LWR. Presently the evaluation of systems reliability is carried out apart from structural reliability analysis. Moreover, two basically different methodologies are used for analysis. While in systems analysis the simplified binary approach is still generally accepted, in structural reliability one has to resort to more sophisticated procedures to obtain realistic results. The interactive effect may be illustrated as follows: For example, the integrity of the primary circuit interacts with the integrity of the containment structure. This means that the probability of occurrence of the pipe rupture which may cause a LOCA and consequently leads to a build-up of temperature and pressure within the containment affects directly its structural reliability. The piping system, particularly the primary piping, in turn interacts with the protective system, which is part of the safety system. This piping structure is also subjected to various operational loading conditions. In a numerical example dealing with leakage probabilities of pipes it is shown how methods of structural reliability may be used to gain more insight in the estimation of failure rates of system components. (orig.)

  12. Design of a decentralized detection of interacting LTI systems

    Directory of Open Access Journals (Sweden)

    Shankar Shamanth

    2002-01-01

    Full Text Available In this paper, the problem of designing a decentralized detection filter for a large homogeneous collection of LTI systems is considered. The collection of systems considered here draws inspiration from platoons of vehicles, and the considered interactions amongst systems in the collection are banded and lower triangular, mimicking the typical “look-ahead” nature of interactions in a platoon of vehicles. A fault in a system propagates to other systems in the collection via such interactions. The decentralized detection filter for the collection is composed of interacting detection filters, one for each system. The feasibility of communicating the state estimates to other systems in the collection is assumed here. An important concern is the propagation of state estimation errors. In order that the state estimation errors not amplify as they propagate, a ℋ ∞ constraint on the state estimation error propagation dynamics is imposed. A sufficient condition for constructing a decentralized detection filter for the collection is presented. An example is provided to illustrate the design procedure.

  13. Human-computer interaction and management information systems

    CERN Document Server

    Galletta, Dennis F

    2014-01-01

    ""Human-Computer Interaction and Management Information Systems: Applications"" offers state-of-the-art research by a distinguished set of authors who span the MIS and HCI fields. The original chapters provide authoritative commentaries and in-depth descriptions of research programs that will guide 21st century scholars, graduate students, and industry professionals. Human-Computer Interaction (or Human Factors) in MIS is concerned with the ways humans interact with information, technologies, and tasks, especially in business, managerial, organizational, and cultural contexts. It is distinctiv

  14. Bifidobacterium breve - HT-29 cell line interaction: modulation of TNF-α induced gene expression.

    Science.gov (United States)

    Boesten, R J; Schuren, F H J; Willemsen, L E M; Vriesema, A; Knol, J; De Vos, W M

    2011-06-01

    To provide insight in the molecular basis for intestinal host-microbe interactions, we determined the genome-wide transcriptional response of human intestinal epithelial cells following exposure to cells of Bifidobacterium breve. To select an appropriate test system reflecting inflammatory conditions, the responsiveness to TNF-α was compared in T84, Caco-2 and HT-29 cells. The highest TNF-α response was observed in HT-29 cells and this cell line was selected for exposure to the B. breve strains M-16V, NR246 and UCC2003. After one hour of bacterial pre-incubation followed by two hours of additional TNF-α stimulation, B. breve M-16V (86%), but to a much lesser extent strains NR246 (50%) or UCC2003 (32%), showed a strain-specific reduction of the HT-29 transcriptional response to the inflammatory treatment. The most important functional groups of genes that were transcriptionally suppressed by the presence of B. breve M-16V, were found to be involved in immune regulation and apoptotic processes. About 54% of the TNF-α induced genes were solely suppressed by the presence of B. breve M-16V. These included apoptosis-related cysteine protease caspase 7 (CASP7), interferon regulatory factor 3 (IRF3), amyloid beta (A4) precursor proteinbinding family A member 1 (APBA1), NADPH oxidase (NOX5), and leukemia inhibitory factor receptor (LIFR). The extracellular IL-8 concentration was determined by an immunological assay but did not change significantly, indicating that B. breve M-16V only partially modulates the TNF-α pathway. In conclusion, this study shows that B. breve strains modulate gene expression in HT-29 cells under inflammatory conditions in a strain-specific way.

  15. Interactive color graphics system for BWR fuel management

    International Nuclear Information System (INIS)

    Reese, A.P.

    1986-01-01

    An interactive color graphics system has been developed by the General Electric Company for fuel management engineers. The system consists of a Hewlett-Packard color graphics workstation in communication with a host mainframe. The system aids in such tasks as fuel cycle optimization, refueling bundle shuffle and control blade sequence design. Since being installed in 1983 turn-around time for a typical cycle reload and control blade pattern design has been reduced by a factor of four

  16. Calogero-Sutherland system with two types interacting spins

    Science.gov (United States)

    Kharchev, S.; Levin, A.; Olshanetsky, M.; Zotov, A.

    2017-08-01

    We consider the classical Calogero-Sutherland system with two types of interacting spin variables. It can be reduced to the standard Calogero-Sutherland system, when one of the spin variables vanishes. We describe the model in the Hitchin approach and prove complete integrability of the system by constructing the Lax pair and the classical r-matrix with the spectral parameter on a singular curve.

  17. Development of 3D browsing and interactive web system

    Science.gov (United States)

    Shi, Xiaonan; Fu, Jian; Jin, Chaolin

    2017-09-01

    In the current market, users need to download specific software or plug-ins to browse the 3D model, and browsing the system may be unstable, and it cannot be 3D model interaction issues In order to solve this problem, this paper presents a solution to the interactive browsing of the model in the server-side parsing model, and when the system is applied, the user only needs to input the system URL and upload the 3D model file to operate the browsing The server real-time parsing 3D model, the interactive response speed, these completely follows the user to walk the minimalist idea, and solves the current market block 3D content development question.

  18. Periodic and quasiperiodic revivals in periodically driven interacting quantum systems

    Science.gov (United States)

    Luitz, David J.; Lazarides, Achilleas; Bar Lev, Yevgeny

    2018-01-01

    Recently it has been shown that interparticle interactions generically destroy dynamical localization in periodically driven systems, resulting in diffusive transport and heating. In this Rapid Communication we rigorously construct a family of interacting driven systems which are dynamically localized and effectively decoupled from the external driving potential. We show that these systems exhibit tunable periodic or quasiperiodic revivals of the many-body wave function and thus of all physical observables. By numerically examining spinless fermions on a one-dimensional lattice we show that the analytically obtained revivals of such systems remain stable for finite systems with open boundary conditions while having a finite lifetime in the presence of static spatial disorder. We find this lifetime to be inversely proportional to the disorder strength.

  19. Extended functions of the database machine FREND for interactive systems

    International Nuclear Information System (INIS)

    Hikita, S.; Kawakami, S.; Sano, K.

    1984-01-01

    Well-designed visual interfaces encourage non-expert users to use relational database systems. In those systems such as office automation systems or engineering database systems, non-expert users interactively access to database from visual terminals. Some users may want to occupy database or other users may share database according to various situations. Because, those jobs need a lot of time to be completed, concurrency control must be well designed to enhance the concurrency. The extended method of concurrency control of FREND is presented in this paper. The authors assume that systems are composed of workstations, a local area network and the database machine FREND. This paper also stresses that those workstations and FREND must cooperate to complete concurrency control for interactive applications

  20. Challenges in designing interactive systems for emergency response

    DEFF Research Database (Denmark)

    Kristensen, Margit; Kyng, Morten; Nielsen, Esben Toftdahl

    2007-01-01

    and visions as ways to bridge between fieldwork and literature studies on the one hand and the emerging computer based prototypes on the other. Our case concerns design of innovative interactive systems for support in emergency response, including patient identification and monitoring as well as construction......This paper presents research on participatory design of interactive systems for emergency response. We present the work by going through the design method with a focus on the new elements that we developed for the participatory design toolkit, in particular we emphasize the use of challenges...

  1. Towards future interactive intelligent systems for animals : Study and recognition of embodied interactions

    NARCIS (Netherlands)

    Pons, Patricia; Jaen, Javier; Catala, Alejandro

    2017-01-01

    User-centered design applied to non-human animals is showing to be a promising research line known as Animal Computer Interaction (ACI), aimed at improving animals' wellbeing using technology. Within this research line, intelligent systems for animal entertainment could have remarkable benefits for

  2. Nonequilibrium statistical mechanics of systems with long-range interactions

    Energy Technology Data Exchange (ETDEWEB)

    Levin, Yan, E-mail: levin@if.ufrgs.br; Pakter, Renato, E-mail: pakter@if.ufrgs.br; Rizzato, Felipe B., E-mail: rizzato@if.ufrgs.br; Teles, Tarcísio N., E-mail: tarcisio.teles@fi.infn.it; Benetti, Fernanda P.C., E-mail: fbenetti@if.ufrgs.br

    2014-02-01

    Systems with long-range (LR) forces, for which the interaction potential decays with the interparticle distance with an exponent smaller than the dimensionality of the embedding space, remain an outstanding challenge to statistical physics. The internal energy of such systems lacks extensivity and additivity. Although the extensivity can be restored by scaling the interaction potential with the number of particles, the non-additivity still remains. Lack of additivity leads to inequivalence of statistical ensembles. Before relaxing to thermodynamic equilibrium, isolated systems with LR forces become trapped in out-of-equilibrium quasi-stationary states (qSSs), the lifetime of which diverges with the number of particles. Therefore, in the thermodynamic limit LR systems will not relax to equilibrium. The qSSs are attained through the process of collisionless relaxation. Density oscillations lead to particle–wave interactions and excitation of parametric resonances. The resonant particles escape from the main cluster to form a tenuous halo. Simultaneously, this cools down the core of the distribution and dampens out the oscillations. When all the oscillations die out the ergodicity is broken and a qSS is born. In this report, we will review a theory which allows us to quantitatively predict the particle distribution in the qSS. The theory is applied to various LR interacting systems, ranging from plasmas to self-gravitating clusters and kinetic spin models.

  3. Identifying User Experience Goals for Interactive Climate Management Business Systems

    DEFF Research Database (Denmark)

    Clemmensen, Torkil; Barlow, Stephanie

    2013-01-01

    This paper presents findings from interpretative phenomenological interviews about the user experience of interactive climate management with six growers and crop consultants. The focus of user experience research has been on quantitative studies of consumers’ initial usage experiences, for example...... of mobile phones or e-commerce websites. In contrast, this empirical paper provides an example of how to capture user experience in work contexts and with a qualitative methodology. We present a model of the essence of the emotional user experience of interactive climate management. Then we suggest...... of interactive climate management in this and other domains. The overall aim with the paper is to take the concept of user experience into the IS community and to describe and understand what are individual workers’ positive emotional use experiences when interacting with workplace systems....

  4. Fluctuation-induced long-range interactions in polymer systems

    International Nuclear Information System (INIS)

    Semenov, A N; Obukhov, S P

    2005-01-01

    We discover a new universal long-range interaction between solid objects in polymer media. This polymer-induced interaction is directly opposite to the van der Waals attraction. The predicted effect is deeply related to the classical Casimir interactions, providing a unique example of universal fluctuation-induced repulsion rather than normal attraction. This universal repulsion comes from the subtracted soft fluctuation modes in the ideal counterpart of the real polymer system. The effect can also be interpreted in terms of subtracted (ghost) large-scale polymer loops. We establish the general expressions for the energy of polymer-induced interactions for arbitrary solid particles in a concentrated polymer system. We find that the correlation function of the polymer density in a concentrated solution of very long chains follows a scaling law rather than an exponential decay at large distances. These novel universal long-range interactions can be of importance in various polymer systems. We discuss the ways to observe/simulate these fluctuation-induced effects

  5. Interactive Mapping on Virtual Terrain Models Using RIMS (Real-time, Interactive Mapping System)

    Science.gov (United States)

    Bernardin, T.; Cowgill, E.; Gold, R. D.; Hamann, B.; Kreylos, O.; Schmitt, A.

    2006-12-01

    Recent and ongoing space missions are yielding new multispectral data for the surfaces of Earth and other planets at unprecedented rates and spatial resolution. With their high spatial resolution and widespread coverage, these data have opened new frontiers in observational Earth and planetary science. But they have also precipitated an acute need for new analytical techniques. To address this problem, we have developed RIMS, a Real-time, Interactive Mapping System that allows scientists to visualize, interact with, and map directly on, three-dimensional (3D) displays of georeferenced texture data, such as multispectral satellite imagery, that is draped over a surface representation derived from digital elevation data. The system uses a quadtree-based multiresolution method to render in real time high-resolution (3 to 10 m/pixel) data over large (800 km by 800 km) spatial areas. It allows users to map inside this interactive environment by generating georeferenced and attributed vector-based elements that are draped over the topography. We explain the technique using 15 m ASTER stereo-data from Iraq, P.R. China, and other remote locations because our particular motivation is to develop a technique that permits the detailed (10 m to 1000 m) neotectonic mapping over large (100 km to 1000 km long) active fault systems that is needed to better understand active continental deformation on Earth. RIMS also includes a virtual geologic compass that allows users to fit a plane to geologic surfaces and thereby measure their orientations. It also includes tools that allow 3D surface reconstruction of deformed and partially eroded surfaces such as folded bedding planes. These georeferenced map and measurement data can be exported to, or imported from, a standard GIS (geographic information systems) file format. Our interactive, 3D visualization and analysis system is designed for those who study planetary surfaces, including neotectonic geologists, geomorphologists, marine

  6. Interactive Rhythm Learning System by Combining Tablet Computers and Robots

    Directory of Open Access Journals (Sweden)

    Chien-Hsing Chou

    2017-03-01

    Full Text Available This study proposes a percussion learning device that combines tablet computers and robots. This device comprises two systems: a rhythm teaching system, in which users can compose and practice rhythms by using a tablet computer, and a robot performance system. First, teachers compose the rhythm training contents on the tablet computer. Then, the learners practice these percussion exercises by using the tablet computer and a small drum set. The teaching system provides a new and user-friendly score editing interface for composing a rhythm exercise. It also provides a rhythm rating function to facilitate percussion training for children and improve the stability of rhythmic beating. To encourage children to practice percussion exercises, a robotic performance system is used to interact with the children; this system can perform percussion exercises for students to listen to and then help them practice the exercise. This interaction enhances children’s interest and motivation to learn and practice rhythm exercises. The results of experimental course and field trials reveal that the proposed system not only increases students’ interest and efficiency in learning but also helps them in understanding musical rhythms through interaction and composing simple rhythms.

  7. Lunar and Martian environmental interactions with nuclear power system radiators

    International Nuclear Information System (INIS)

    Perez-Davis, M.E.; Gaier, J.R.; Katzan, C.M.

    1994-01-01

    In the foreseeable future, NASA space milestones include a permanent manned presence on the Moon and an expedition to the planet Mars. Such steps will require careful consideration of environmental interactions in the selection and design of required power systems. Several environmental constituents may be hazardous to performance integrity. Potential threats common to both the Moon and Mars are low ambient temperatures, wide daily temperature swings, solar flux, and large quantities of dust. The surface of Mars provides the additional challenges of dust storms, winds, and a carbon dioxide atmosphere. In this review, the anticipated environmental interactions with surface power system radiators are described, as well as the impacts of these interactions on radiator durability, which have been identified at NASA Lewis Research Center

  8. Towards a systems understanding of plant-microbe interactions

    Directory of Open Access Journals (Sweden)

    Akira eMine

    2014-08-01

    Full Text Available Plants are closely associated with microorganisms including pathogens and mutualists that influence plant fitness. Molecular genetic approaches have uncovered a number of signaling components from both plants and microbes and their mode of actions. However, signaling pathways are highly interconnected and influenced by diverse sets of environmental factors. Therefore, it is important to have systems views in order to understand the true nature of plant-microbe interactions. Indeed, systems biology approaches have revealed previously overlooked or misinterpreted properties of the plant immune signaling network. Experimental reconstruction of biological networks using exhaustive combinatorial mutants is particularly powerful to elucidate network structure and properties and relationships among network components. Recent advances in metagenomics of microbial communities associated with plants further point to the importance of systems approaches and open a research area of microbial community reconstruction. In this review, we highlight the importance of a systems understanding of plant-microbe interactions, with a special emphasis on reconstruction strategies.

  9. Request queues for interactive clients in a shared file system of a parallel computing system

    Science.gov (United States)

    Bent, John M.; Faibish, Sorin

    2015-08-18

    Interactive requests are processed from users of log-in nodes. A metadata server node is provided for use in a file system shared by one or more interactive nodes and one or more batch nodes. The interactive nodes comprise interactive clients to execute interactive tasks and the batch nodes execute batch jobs for one or more batch clients. The metadata server node comprises a virtual machine monitor; an interactive client proxy to store metadata requests from the interactive clients in an interactive client queue; a batch client proxy to store metadata requests from the batch clients in a batch client queue; and a metadata server to store the metadata requests from the interactive client queue and the batch client queue in a metadata queue based on an allocation of resources by the virtual machine monitor. The metadata requests can be prioritized, for example, based on one or more of a predefined policy and predefined rules.

  10. Weak solutions for Euler systems with non-local interactions

    Czech Academy of Sciences Publication Activity Database

    Carrillo, J. A.; Feireisl, Eduard; Gwiazda, P.; Swierczewska-Gwiazda, A.

    2017-01-01

    Roč. 95, č. 3 (2017), s. 705-724 ISSN 0024-6107 EU Projects: European Commission(XE) 320078 - MATHEF Institutional support: RVO:67985840 Keywords : Euler system * dissipative solutions * Newtonian interaction Subject RIV: BA - General Mathematics OBOR OECD: Pure mathematics Impact factor: 0.895, year: 2016 http://onlinelibrary.wiley.com/doi/10.1112/jlms.12027/abstract

  11. Long-range interactions in dilute granular systems

    NARCIS (Netherlands)

    Müller, M.K

    2008-01-01

    In this thesis, on purpose, we focussed on the most challenging, longest ranging potentials. We analyzed granular media of low densities obeying 1/r long-range interaction potentials between the granules. Such systems are termed granular gases and differ in their behavior from ordinary gases by

  12. Component Based System Framework for Dynamic B2B Interaction

    NARCIS (Netherlands)

    Hu jinmin, Jinmin; Grefen, P.W.P.J.

    Business-to-Business (B2B) collaboration is becoming a pivotal way to bring today's enterprises to success in the dynamically changing e-business environment. Though many business-to-business protocols are developed to support B2B interaction, none are generally accepted. A B2B system should support

  13. Robust collaborative process interactions under system crash and network failures

    NARCIS (Netherlands)

    Wang, Lei; Wombacher, Andreas; Ferreira Pires, Luis; van Sinderen, Marten J.; Chi, Chihung

    2013-01-01

    With the possibility of system crashes and network failures, the design of robust client/server interactions for collaborative process execution is a challenge. If a business process changes its state, it sends messages to the relevant processes to inform about this change. However, server crashes

  14. Neuronal chemokines : Versatile messengers in central nervous system cell interaction

    NARCIS (Netherlands)

    de Haas, A. H.; van Weering, H. R. J.; de Jong, E. K.; Boddeke, H. W. G. M.; Biber, K. P. H.

    2007-01-01

    Whereas chemokines are well known for their ability to induce cell migration, only recently it became evident that chemokines also control a variety of other cell functions and are versatile messengers in the interaction between a diversity of cell types. In the central nervous system (CNS),

  15. Quantum chaos and thermalization in isolated systems of interacting particles

    Energy Technology Data Exchange (ETDEWEB)

    Borgonovi, F., E-mail: fausto.borgonovi@unicatt.it [Dipartimento di Matematica e Fisica and Interdisciplinary Laboratories for Advanced Materials Physics, Universitá Cattolica, via Musei 41, 25121 Brescia, and INFN, Sezione di Pavia (Italy); Izrailev, F.M., E-mail: felix.izrailev@gmail.com [Instituto de Física, Universidad Autónoma de Puebla, Apt. Postal J-48, Puebla, Pue., 72570 (Mexico); NSCL and Department of Physics and Astronomy, Michigan State University, East Lansing, MI 48824-1321 (United States); Santos, L.F., E-mail: lsantos2@yu.edu [Department of Physics, Yeshiva University, 245 Lexington Ave, New York, NY 10016 (United States); Zelevinsky, V.G., E-mail: Zelevins@nscl.msu.edu [NSCL and Department of Physics and Astronomy, Michigan State University, East Lansing, MI 48824-1321 (United States)

    2016-04-15

    This review is devoted to the problem of thermalization in a small isolated conglomerate of interacting constituents. A variety of physically important systems of intensive current interest belong to this category: complex atoms, molecules (including biological molecules), nuclei, small devices of condensed matter and quantum optics on nano- and micro-scale, cold atoms in optical lattices, ion traps. Physical implementations of quantum computers, where there are many interacting qubits, also fall into this group. Statistical regularities come into play through inter-particle interactions, which have two fundamental components: mean field, that along with external conditions, forms the regular component of the dynamics, and residual interactions responsible for the complex structure of the actual stationary states. At sufficiently high level density, the stationary states become exceedingly complicated superpositions of simple quasiparticle excitations. At this stage, regularities typical of quantum chaos emerge and bring in signatures of thermalization. We describe all the stages and the results of the processes leading to thermalization, using analytical and massive numerical examples for realistic atomic, nuclear, and spin systems, as well as for models with random parameters. The structure of stationary states, strength functions of simple configurations, and concepts of entropy and temperature in application to isolated mesoscopic systems are discussed in detail. We conclude with a schematic discussion of the time evolution of such systems to equilibrium.

  16. Multi-class oscillating systems of interacting neurons

    DEFF Research Database (Denmark)

    Ditlevsen, Susanne; Löcherbach, Eva

    2017-01-01

    We consider multi-class systems of interacting nonlinear Hawkes processes modeling several large families of neurons and study their mean field limits. As the total number of neurons goes to infinity we prove that the evolution within each class can be described by a nonlinear limit differential...

  17. Supporting Social Interaction in Intelligent Competence Development Systems

    NARCIS (Netherlands)

    Sereno, Bertrand; Boursinou, Eleni; Maxwell, Katrina; Angehrn, Albert

    2007-01-01

    Sereno, B., Boursinou, E., Maxwell, K., & Angehrn, A. A. (2007). Supporting Social Interaction in Intelligent Competence Development Systems. In D. Griffiths, R. Koper & O. Liber (Eds.), Proceedings of the 2nd TENCompetence Open Workshop (pp. 29-35). January, 11-12, 2007, Manchester, United Kingdom.

  18. Interaction of Air Flow in Complex Ventilation Systems

    Directory of Open Access Journals (Sweden)

    Zhorzh G. Levitskiy

    2013-01-01

    Full Text Available The article presents the results of study of interaction of air flow in complex ventilation systems. The study used Taylor and Maclaurin’s series and Lagrange formula to create the functional connections on estimation of the impact of changing aerodynamic parameters of one or several simultaneously working regulators on the air flow distribution in mines

  19. Comparative modeling for power generating systems with interaction phenomena

    International Nuclear Information System (INIS)

    Kim, Seong Ho; Kim, Tae Woon

    2007-01-01

    From a conflicting viewpoint, comprehensive assessment of various national power systems can be treated as a multicriteria decision-making (MCDM) problem. In reality, there are interaction phenomena among the decision elements. The main objective of this work is to propose a comprehensive framework to determinate the priority of appropriate national power sources involving various degrees of interaction among the decision elements (e.g., decision goal, decision criteria, and decision alternatives) such as inner dependence, outer dependence, and feedback effect. In the context of a generic hierarchical network (or hiernet) structure instead of one-way directional tree structure, the impact of the interaction phenomena on the grade of priority is investigated using a supermatrix technique or an analytic network process (ANP) method. Moreover, the three types of attitudes towards nuclear power system of the multiple actors are incorporated into the network structure to figure out the effect of characteristics of power systems. An illustrative example of the generic hiernet structure is demonstrated in comparison to the specific hierarchy structure without any interaction among the decision elements. The proposed framework can be applied to select the appropriate power systems, to understand the effect of its underlying decision structures, and to include risk attitudes towards a certain alternative. (author)

  20. Monitoring User-System Performance in Interactive Retrieval Tasks

    NARCIS (Netherlands)

    Boldareva, L.; de Vries, A.P.; Hiemstra, Djoerd

    Monitoring user-system performance in interactive search is a challenging task. Traditional measures of retrieval evaluation, based on recall and precision, are not of any use in real time, for they require a priori knowledge of relevant documents. This paper shows how a Shannon entropy-based

  1. Gravitational radiation quadrupole formula is valid for gravitationally interacting systems

    International Nuclear Information System (INIS)

    Walker, M.; Will, C.M.

    1980-01-01

    An argument is presented for the validity of the quadrupole formula for gravitational radiation energy loss in the far field of nearly Newtonian (e.g., binary stellar) systems. This argument differs from earlier ones in that it determines beforehand the formal accuracy of approximation required to describe gravitationally self-interacting systems, uses the corresponding approximate equation of motion explicitly, and evaluate the appropriate asymptotic quantities by matching along the correct space-time light cones

  2. Interactive Control System, Intended Strategy, Implemented Strategy dan Emergent Strategy

    OpenAIRE

    Tubagus Ismail; Darjat Sudrajat

    2012-01-01

    The purpose of this study was to examine the relationship between management control system (MCS) and strategy formation processes, namely: intended strategy, emergent strategy and impelemented strategy. The focus of MCS in this study was interactive control system. The study was based on Structural Equation Modeling (SEM) as its multivariate analyses instrument. The samples were upper middle managers of manufacturing company in Banten Province, DKI Jakarta Province and West Java Province. AM...

  3. Heat transfer and mechanical interactions in fusion nuclear systems

    International Nuclear Information System (INIS)

    Nygren, R.E.

    1984-01-01

    This general review of design issues in heat transfer and mechanical interactions of the first wall, blanket and shield systems of tokamak and mirror fusion reactors begins with a brief introduction to fusion nuclear systems. The design issues are summarized in tables and the following examples are described to illustrate these concerns: the surface heating of limiters, heat transfer from solid breeders, MHD effects in liquid metal blankets, mechanical loads from electromagnetic transients and remote maintenance

  4. CADRIGS--computer aided design reliability interactive graphics system

    International Nuclear Information System (INIS)

    Kwik, R.J.; Polizzi, L.M.; Sticco, S.; Gerrard, P.B.; Yeater, M.L.; Hockenbury, R.W.; Phillips, M.A.

    1982-01-01

    An integrated reliability analysis program combining graphic representation of fault trees, automated data base loadings and reference, and automated construction of reliability code input files was developed. The functional specifications for CADRIGS, the computer aided design reliability interactive graphics system, are presented. Previously developed fault tree segments used in auxiliary feedwater system safety analysis were constructed on CADRIGS and, when combined, yielded results identical to those resulting from manual input to the same reliability codes

  5. Nonlinear degenerate cross-diffusion systems with nonlocal interaction

    OpenAIRE

    Di Francesco, M.; Esposito, A.; Fagioli, S.

    2017-01-01

    We investigate a class of systems of partial differential equations with nonlinear cross-diffusion and nonlocal interactions, which are of interest in several contexts in social sciences, finance, biology, and real world applications. Assuming a uniform "coerciveness" assumption on the diffusion part, which allows to consider a large class of systems with degenerate cross-diffusion (i.e. of porous medium type) and relaxes sets of assumptions previously considered in the literature, we prove g...

  6. CDP a graphic system for the interactive simulation and the dynamic analysis of continuous systems

    International Nuclear Information System (INIS)

    Ricci, A.; Teolis, A.

    1973-01-01

    An IBM 2250 graphic system for the interactive simulation of continuous sytems is illustrated. Time dependent quantities can be plotted or an animated, real or schematic, representation of the system being studied can be given

  7. Autonomic nervous system mediated effects of food intake. Interaction between gastrointestinal and cardiovascular systems.

    NARCIS (Netherlands)

    van Orshoven, N.P.

    2008-01-01

    The studies presented in this thesis focused on the autonomic nervous system mediated interactions between the gastrointestinal and cardiovascular systems in response to food intake and on potential consequences of failure of these interactions. The effects of food intake on cardiovascular

  8. Magnetic interactions in strongly correlated systems: Spin and orbital contributions

    Energy Technology Data Exchange (ETDEWEB)

    Secchi, A., E-mail: a.secchi@science.ru.nl [Radboud University, Institute for Molecules and Materials, 6525 AJ Nijmegen (Netherlands); Lichtenstein, A.I. [Universitat Hamburg, Institut für Theoretische Physik, Jungiusstraße 9, D-20355 Hamburg (Germany); Katsnelson, M.I. [Radboud University, Institute for Molecules and Materials, 6525 AJ Nijmegen (Netherlands)

    2015-09-15

    We present a technique to map an electronic model with local interactions (a generalized multi-orbital Hubbard model) onto an effective model of interacting classical spins, by requiring that the thermodynamic potentials associated to spin rotations in the two systems are equivalent up to second order in the rotation angles, when the electronic system is in a symmetry-broken phase. This allows to determine the parameters of relativistic and non-relativistic magnetic interactions in the effective spin model in terms of equilibrium Green’s functions of the electronic model. The Hamiltonian of the electronic system includes, in addition to the non-relativistic part, relativistic single-particle terms such as the Zeeman coupling to an external magnetic field, spin–orbit coupling, and arbitrary magnetic anisotropies; the orbital degrees of freedom of the electrons are explicitly taken into account. We determine the complete relativistic exchange tensors, accounting for anisotropic exchange, Dzyaloshinskii–Moriya interactions, as well as additional non-diagonal symmetric terms (which may include dipole–dipole interaction). The expressions of all these magnetic interactions are determined in a unified framework, including previously disregarded features such as the vertices of two-particle Green’s functions and non-local self-energies. We do not assume any smallness in spin–orbit coupling, so our treatment is in this sense exact. Finally, we show how to distinguish and address separately the spin, orbital and spin–orbital contributions to magnetism, providing expressions that can be computed within a tight-binding Dynamical Mean Field Theory.

  9. Synchronization in human musical rhythms and mutually interacting complex systems.

    Science.gov (United States)

    Hennig, Holger

    2014-09-09

    Though the music produced by an ensemble is influenced by multiple factors, including musical genre, musician skill, and individual interpretation, rhythmic synchronization is at the foundation of musical interaction. Here, we study the statistical nature of the mutual interaction between two humans synchronizing rhythms. We find that the interbeat intervals of both laypeople and professional musicians exhibit scale-free (power law) cross-correlations. Surprisingly, the next beat to be played by one person is dependent on the entire history of the other person's interbeat intervals on timescales up to several minutes. To understand this finding, we propose a general stochastic model for mutually interacting complex systems, which suggests a physiologically motivated explanation for the occurrence of scale-free cross-correlations. We show that the observed long-term memory phenomenon in rhythmic synchronization can be imitated by fractal coupling of separately recorded or synthesized audio tracks and thus applied in electronic music. Though this study provides an understanding of fundamental characteristics of timing and synchronization at the interbrain level, the mutually interacting complex systems model may also be applied to study the dynamics of other complex systems where scale-free cross-correlations have been observed, including econophysics, physiological time series, and collective behavior of animal flocks.

  10. Interactions of nanomaterials and biological systems: implications to personalized nanomedicine☆

    Science.gov (United States)

    Zhang, Xue-Qing; Xu, Xiaoyang; Bertrand, Nicolas; Pridgen, Eric; Swami, Archana; Farokhzad, Omid C.

    2012-01-01

    The application of nanotechnology to personalized medicine provides an unprecedented opportunity to improve the treatment of many diseases. Nanomaterials offer several advantages as therapeutic and diagnostic tools due to design flexibility, small sizes, large surface-to-volume ratio, and ease of surface modification with multivalent ligands to increase avidity for target molecules. Nanomaterials can be engineered to interact with specific biological components, allowing them to benefit from the insights provided by personalized medicine techniques. To tailor these interactions, a comprehensive knowledge of how nanomaterials interact with biological systems is critical. Herein, we discuss how the interactions of nanomaterials with biological systems can guide their design for diagnostic, imaging and drug delivery purposes. A general overview of nanomaterials under investigation is provided with an emphasis on systems that have reached clinical trials. Finally, considerations for the development of personalized nanomedicines are summarized such as the potential toxicity, scientific and technical challenges in fabricating them, and regulatory and ethical issues raised by the utilization of nanomaterials. PMID:22917779

  11. Non-equilibrium magnetic interactions in strongly correlated systems

    Energy Technology Data Exchange (ETDEWEB)

    Secchi, A., E-mail: a.secchi@science.ru.nl [Institute for Molecules and Materials, Radboud University Nijmegen, 6525 AJ Nijmegen (Netherlands); Brener, S.; Lichtenstein, A.I. [Institut für Theoretische Physik, Universitat Hamburg, Jungiusstraße 9, D-20355 Hamburg (Germany); Katsnelson, M.I. [Institute for Molecules and Materials, Radboud University Nijmegen, 6525 AJ Nijmegen (Netherlands)

    2013-06-15

    We formulate a low-energy theory for the magnetic interactions between electrons in the multi-band Hubbard model under non-equilibrium conditions determined by an external time-dependent electric field which simulates laser-induced spin dynamics. We derive expressions for dynamical exchange parameters in terms of non-equilibrium electronic Green functions and self-energies, which can be computed, e.g., with the methods of time-dependent dynamical mean-field theory. Moreover, we find that a correct description of the system requires, in addition to exchange, a new kind of magnetic interaction, that we name twist exchange, which formally resembles Dzyaloshinskii–Moriya coupling, but is not due to spin–orbit, and is actually due to an effective three-spin interaction. Our theory allows the evaluation of the related time-dependent parameters as well. -- Highlights: •We develop a theory for magnetism of strongly correlated systems out of equilibrium. •Our theory is suitable for laser-induced ultrafast magnetization dynamics. •We write time-dependent exchange parameters in terms of electronic Green functions. •We find a new magnetic interaction, a “twist exchange”. •We give general expressions for magnetic noise in itinerant-electron systems.

  12. Magnetic impurity in a system of interacting electrons

    International Nuclear Information System (INIS)

    Huynh Thanh Duc; Nguyen Toan Thang

    1999-04-01

    The Kondo effect of the Anderson impurity in a correlated conduction electron system is studied within the slave boson mean-field theory. The interacting conduction electrons are described by a Hubbard model with an interaction of strength U. It is shown that the Kondo temperature T K decreases with an increase of U. In the intermediate regime at half-filling the exponential scale of the Kondo temperature T K is lost already at the saddle-point level of slave boson formulation. (author)

  13. Pareto-Zipf law in growing systems with multiplicative interactions

    Science.gov (United States)

    Ohtsuki, Toshiya; Tanimoto, Satoshi; Sekiyama, Makoto; Fujihara, Akihiro; Yamamoto, Hiroshi

    2018-06-01

    Numerical simulations of multiplicatively interacting stochastic processes with weighted selections were conducted. A feedback mechanism to control the weight w of selections was proposed. It becomes evident that when w is moderately controlled around 0, such systems spontaneously exhibit the Pareto-Zipf distribution. The simulation results are universal in the sense that microscopic details, such as parameter values and the type of control and weight, are irrelevant. The central ingredient of the Pareto-Zipf law is argued to be the mild control of interactions.

  14. Interactive augmented reality system for product design review

    Science.gov (United States)

    Caruso, Giandomenico; Re, Guido Maria

    2010-01-01

    The product development process, of industrial products, includes a phase dedicated to the design review that is a crucial phase where various experts cooperate in selecting the optimal product shape. Although computer graphics allows us to create very realistic virtual representations of the products, it is not uncommon that designers decide to build physical mock-ups of their newly conceived products because they need to physically interact with the prototype and also to evaluate the product within a plurality of real contexts. This paper describes the hardware and software development of our Augmented Reality design review system that allows to overcome some issues related to the 3D visualization and to the interaction with the virtual objects. Our system is composed by a Video See Through Head Mounted Display, which allows to improve the 3D visualization by controlling the convergence of the video cameras automatically, and a wireless control system, which allows us to create some metaphors to interact with the virtual objects. During the development of the system, in order to define and tune the algorithms, we have performed some testing sessions. Then, we have performed further tests in order to verify the effectiveness of the system and to collect additional data and comments about usability and ergonomic aspects.

  15. Analysis of the interaction of participants freight forwarding system

    Directory of Open Access Journals (Sweden)

    Pavlo Popovych

    2016-12-01

    Full Text Available Main goal of this work is the analysis of the interaction of participants of freight forwarding activities. Research methods included analysis of scientific literature, theory of systems and systems analysis, methods of induction and deduction. As sources of information used and applied work of fundamental importance known foreign and local scientists and regulatory and legislative documents of Ukraine for the state transport policy. In the article the basic interactions of participants of freight forwarding activities. Classified components freight forwarding services. Assign the concept freight forwarding system and its aim. Established element and forms of cooperation in the freight forwarding system. The main task of forwarding companies are organizing, coordinating and ensuring the delivery from shipper to consignee. Freight forwarding company responsible for the timely delivery of the goods on the condition of preservation of the quantity and quality specified time conditions. Currently used methods are uneffective decision-making, leading to losses. These circumstances require improvement methodology management of freight forwarding companies. This is possible only using modern mathematical methods and information technologies that will improve the operation of freight forwarding companies. The article presents a theoretical exposition of the basic processes of interaction between participants in freight forwarding system. The article may be of interest to specialists of freight forwarding companies.

  16. Human-computer systems interaction backgrounds and applications 3

    CERN Document Server

    Kulikowski, Juliusz; Mroczek, Teresa; Wtorek, Jerzy

    2014-01-01

    This book contains an interesting and state-of the art collection of papers on the recent progress in Human-Computer System Interaction (H-CSI). It contributes the profound description of the actual status of the H-CSI field and also provides a solid base for further development and research in the discussed area. The contents of the book are divided into the following parts: I. General human-system interaction problems; II. Health monitoring and disabled people helping systems; and III. Various information processing systems. This book is intended for a wide audience of readers who are not necessarily experts in computer science, machine learning or knowledge engineering, but are interested in Human-Computer Systems Interaction. The level of particular papers and specific spreading-out into particular parts is a reason why this volume makes fascinating reading. This gives the reader a much deeper insight than he/she might glean from research papers or talks at conferences. It touches on all deep issues that ...

  17. An Interactive Energy System with Grid, Heating and Transportation Systems

    DEFF Research Database (Denmark)

    Diaz de Cerio Mendaza, Iker

    is required. The models developed in this thesis include different features (thermal, mechanical, chemical…) which are not normally considered in the traditional power system modelling. In this sense, they are intended to serve as a reference for the new researchers starting in the field. Moreover, the grid....... In this situation, not only the security and reliability of these networks are in danger, the flexibility offered by the active loads may also be limited. It is then decisive, to understand what is the hosting capability of this networks and their vulnerable points. In this stage of the thesis, a methodology...... commitments, taking advantage of the flexible demand, while ensuring the security and reliability of the LV network each moment of the day. A proper demand response strategy makes possible to obtain economic benefits from the balancing service provision while decongesting the LV network in critical moments....

  18. Modelling the Interaction Levels in HCI Using an Intelligent Hybrid System with Interactive Agents: A Case Study of an Interactive Museum Exhibition Module in Mexico

    Directory of Open Access Journals (Sweden)

    Ricardo Rosales

    2018-03-01

    Full Text Available Technology has become a necessity in our everyday lives and essential for completing activities we typically take for granted; technologies can assist us by completing set tasks or achieving desired goals with optimal affect and in the most efficient way, thereby improving our interactive experiences. This paper presents research that explores the representation of user interaction levels using an intelligent hybrid system approach with agents. We evaluate interaction levels of Human-Computer Interaction (HCI with the aim of enhancing user experiences. We consider the description of interaction levels using an intelligent hybrid system to provide a decision-making system to an agent that evaluates interaction levels when using interactive modules of a museum exhibition. The agents represent a high-level abstraction of the system, where communication takes place between the user, the exhibition and the environment. In this paper, we provide a means to measure the interaction levels and natural behaviour of users, based on museum user-exhibition interaction. We consider that, by analysing user interaction in a museum, we can help to design better ways to interact with exhibition modules according to the properties and behaviour of the users. An interaction-evaluator agent is proposed to achieve the most suitable representation of the interaction levels with the aim of improving user interactions to offer the most appropriate directions, services, content and information, thereby improving the quality of interaction experienced between the user-agent and exhibition-agent.

  19. Contractive relaxation systems and interacting particles for scalar conservation laws

    International Nuclear Information System (INIS)

    Katsoulakis, M.A.; Tzavaras, A.E.

    1996-01-01

    We consider a class of semi linear hyperbolic systems with relaxation that are contractive in the L 1 -norm and admit invariant regions. We show that, as the relaxation parameter ξ goes to zero, their solutions converge to a weak solution of the scalar multidimensional conversation law that satisfies the Kruzhkov conditions. In the case of one space dimension, we propose certain interacting particle systems, whose mesoscopic limit is the systems with relaxation and their macroscopic dynamics is described by entropy solutions of a scalar conservation law. (author)

  20. Interactive Voice/Web Response System in clinical research.

    Science.gov (United States)

    Ruikar, Vrishabhsagar

    2016-01-01

    Emerging technologies in computer and telecommunication industry has eased the access to computer through telephone. An Interactive Voice/Web Response System (IxRS) is one of the user friendly systems for end users, with complex and tailored programs at its backend. The backend programs are specially tailored for easy understanding of users. Clinical research industry has experienced revolution in methodologies of data capture with time. Different systems have evolved toward emerging modern technologies and tools in couple of decades from past, for example, Electronic Data Capture, IxRS, electronic patient reported outcomes, etc.

  1. Haldane's statistical interactions and universal properties of anyon systems

    International Nuclear Information System (INIS)

    Protogenov, A.

    1995-03-01

    The exclusion principle of fractional statistics proposed by Haldane is applied to systems with internal degrees of freedom. The symmetry of these systems is included in the statistical interaction matrix which contains the Cartan matrix of Lie algebras. The solutions of the equations for the statistical weights, which coincide with the thermodynamic Bethe ansatz equations are determined in the high temperature limit by the squares of q-deformed dimensions of irreducible representations. The entropy and other thermodynamic properties of anyon systems in this limit are completely characterized by the algebraic structure of symmetry in the universal form. (author). 39 refs

  2. Interactive display of molecular models using a microcomputer system

    Science.gov (United States)

    Egan, J. T.; Macelroy, R. D.

    1980-01-01

    A simple, microcomputer-based, interactive graphics display system has been developed for the presentation of perspective views of wire frame molecular models. The display system is based on a TERAK 8510a graphics computer system with a display unit consisting of microprocessor, television display and keyboard subsystems. The operating system includes a screen editor, file manager, PASCAL and BASIC compilers and command options for linking and executing programs. The graphics program, written in USCD PASCAL, involves the centering of the coordinate system, the transformation of centered model coordinates into homogeneous coordinates, the construction of a viewing transformation matrix to operate on the coordinates, clipping invisible points, perspective transformation and scaling to screen coordinates; commands available include ZOOM, ROTATE, RESET, and CHANGEVIEW. Data file structure was chosen to minimize the amount of disk storage space. Despite the inherent slowness of the system, its low cost and flexibility suggests general applicability.

  3. An integrated system for interactive continuous learning of categorical knowledge

    Science.gov (United States)

    Skočaj, Danijel; Vrečko, Alen; Mahnič, Marko; Janíček, Miroslav; Kruijff, Geert-Jan M.; Hanheide, Marc; Hawes, Nick; Wyatt, Jeremy L.; Keller, Thomas; Zhou, Kai; Zillich, Michael; Kristan, Matej

    2016-09-01

    This article presents an integrated robot system capable of interactive learning in dialogue with a human. Such a system needs to have several competencies and must be able to process different types of representations. In this article, we describe a collection of mechanisms that enable integration of heterogeneous competencies in a principled way. Central to our design is the creation of beliefs from visual and linguistic information, and the use of these beliefs for planning system behaviour to satisfy internal drives. The system is able to detect gaps in its knowledge and to plan and execute actions that provide information needed to fill these gaps. We propose a hierarchy of mechanisms which are capable of engaging in different kinds of learning interactions, e.g. those initiated by a tutor or by the system itself. We present the theory these mechanisms are build upon and an instantiation of this theory in the form of an integrated robot system. We demonstrate the operation of the system in the case of learning conceptual models of objects and their visual properties.

  4. Environmental interactions and the SP-100 power system

    International Nuclear Information System (INIS)

    Ferguson, D.C.

    1993-01-01

    The Civil Space Technology Initiative High-Capacity-Power Environmental Interactions Program has made great progress in defining and evaluating the interactions of the SP-100 power system with its expected ambient environments. The NASCAP/LEO and POLAR computer codes demonstrated that local electric fields at the user interface module are high. Therefore, particular attention must be paid to geometries and materials in this region to prevent arcing at conductor-insulator junctions in low Earth orbit. NASCAP/LEO and EPSAT computer models revealed that SP-100 payloads float about 100 V negative of the LEO plasma. In addition, ground tests and modeling done for the Space Station Freedom Electrical Grounding Tiger Team found that dielectric coatings often break down at such voltages in a plasma. Thus, surface coatings for SP-100 payloads should be carefully selected. Sputtering may also be a concern for long-duration missions in LEO at these voltages. Much work has been done on a sputtering model to evaluate surface material loss rates on SP-100 payloads. In ground plasma chamber tests of cables and cable insulators at SP-100 voltages, parasitic power losses due to the plasma current collected from possible pinholes or coating defects were quantified and shown to be small. Modeling revealed that the power loss from currents to other surfaces is also small. The atomic oxygen durability of SP-100 materials and coatings continues to be investigated in ground tests. In the upcoming Evaluation of Oxygen Interaction with Materials (EOIM-3) Shuttle flight experiment, a host of SP-100 materials will be evaluated for atomic oxygen durability in LEO. Finally, an evaluation of the interactions of the SP-100 power system with lunar and planetary environments has started. At a workshop on chemical and electrical interactions on Mars recently held at the NASA Lewis Research Center, many of primary interactions were identified

  5. Plasma surface interactions in Q-enhanced mirror systems

    International Nuclear Information System (INIS)

    Post, R.F.

    1978-01-01

    Two approaches to enhancement of the Q (energy gain) factor of mirror systems are under study at Livermore. These include the Tandem Mirror and the Field Reversed Mirror. Both of these new ideas preserve features of conventional mirror systems as far as plasma-wall interactions are concerned. Specifically in both approaches field lines exit from the ends of the system and impinge on walls located at a distance from the confinement chamber. It is possible to predict some aspects of the plasma/surface interactions of TM and FRM systems from experience obtained in the Livermore 2XIIB experiment. In particular, as observed in 2XIIB, effective isolation of the plasma from thermal contact with the ends owing to the development of sheath-like regions is to be expected. Studies presently underway directed toward still further enhancing the decoupling of the plasma from the effects of plasma surface interactions at the walls will be discussed, with particular reference to the problem of minimizing the effects of refluxing secondary electrons produced by plasma impact on the end walls

  6. PROCEEDINGS OF THE WORKSHOP ON LHC INTERACTION REGION CORRECTION SYSTEMS

    International Nuclear Information System (INIS)

    FISCHER, W.; WEI, J.

    1999-01-01

    The Workshop on LHC Interaction Region Correction Systems was held at Brookhaven National Laboratory, Upton, New York, on 6 and 7 May 1999. It was attended by 25 participants from 5 institutions. The performance of the Large Hadron Collider (LHC) at collision energy is limited by the field quality of the interaction region quadrupoles and dipoles. In three sessions the workshop addressed the field quality of the these magnets, reviewed the principles and efficiency of global and local correction schemes and finalized a corrector layout. The session on Field Quality Issues, chaired by J. Strait (FNAL), discussed the progress made by KEK and FNAL in achieving the best possible field quality in the interaction region quadrupoles. Results of simulation studies were presented that assess the effects of magnetic field errors with simulation studies. Attention was given to the uncertainties in predicting and measuring field errors. The session on Global Correction, chaired by J.-P. Koutchouk (CERN), considered methods of reducing the nonlinear detuning or resonance driving terms in the accelerator one-turn map by either sorting or correcting. The session also discussed the crossing angle dependence of the dynamic aperture and operational experience from LEP. The session on Local Correction, chaired by T. Taylor (CERN), discussed the location, strength and effectiveness of multipole correctors in the interaction regions for both proton and heavy ion operation. Discussions were based on technical feasibility considerations and dynamic aperture requirements. The work on linear corrections in the interaction regions was reviewed

  7. Interplay of Anderson localization and strong interaction in disordered systems

    International Nuclear Information System (INIS)

    Henseler, Peter

    2010-01-01

    We study the interplay of disorder localization and strong local interactions within the Anderson-Hubbard model. Taking into account local Mott-Hubbard physics and static screening of the disorder potential, the system is mapped onto an effective single-particle Anderson model, which is studied within the self-consistent theory of electron localization. For fermions, we find rich nonmonotonic behavior of the localization length ξ, particularly in two-dimensional systems, including an interaction-induced exponential enhancement of ξ for small and intermediate disorders and a strong reduction of ξ due to hopping suppression by strong interactions. In three dimensions, we identify for half filling a Mott-Hubbard-assisted Anderson localized phase existing between the metallic and the Mott-Hubbard-gapped phases. For small U there is re-entrant behavior from the Anderson localized phase to the metallic phase. For bosons, the unrestricted particle occupation number per lattice site yields a monotonic enhancement of ξ as a function of decreasing interaction, which we assume to persist until the superfluid Bose-Einstein condensate phase is entered. Besides, we study cold atomic gases expanding, by a diffusion process, in a weak random potential. We show that the density-density correlation function of the expanding gas is strongly affected by disorder and we estimate the typical size of a speckle spot, i.e., a region of enhanced or depleted density. Both a Fermi gas and a Bose-Einstein condensate (in a mean-field approach) are considered. (orig.)

  8. Interplay of Anderson localization and strong interaction in disordered systems

    Energy Technology Data Exchange (ETDEWEB)

    Henseler, Peter

    2010-01-15

    We study the interplay of disorder localization and strong local interactions within the Anderson-Hubbard model. Taking into account local Mott-Hubbard physics and static screening of the disorder potential, the system is mapped onto an effective single-particle Anderson model, which is studied within the self-consistent theory of electron localization. For fermions, we find rich nonmonotonic behavior of the localization length {xi}, particularly in two-dimensional systems, including an interaction-induced exponential enhancement of {xi} for small and intermediate disorders and a strong reduction of {xi} due to hopping suppression by strong interactions. In three dimensions, we identify for half filling a Mott-Hubbard-assisted Anderson localized phase existing between the metallic and the Mott-Hubbard-gapped phases. For small U there is re-entrant behavior from the Anderson localized phase to the metallic phase. For bosons, the unrestricted particle occupation number per lattice site yields a monotonic enhancement of {xi} as a function of decreasing interaction, which we assume to persist until the superfluid Bose-Einstein condensate phase is entered. Besides, we study cold atomic gases expanding, by a diffusion process, in a weak random potential. We show that the density-density correlation function of the expanding gas is strongly affected by disorder and we estimate the typical size of a speckle spot, i.e., a region of enhanced or depleted density. Both a Fermi gas and a Bose-Einstein condensate (in a mean-field approach) are considered. (orig.)

  9. Theoretical Studies of Strongly Interacting Fine Particle Systems

    Science.gov (United States)

    Fearon, Michael

    Available from UMI in association with The British Library. A theoretical analysis of the time dependent behaviour of a system of fine magnetic particles as a function of applied field and temperature was carried out. The model used was based on a theory assuming Neel relaxation with a distribution of particle sizes. This theory predicted a linear variation of S_{max} with temperature and a finite intercept, which is not reflected by experimental observations. The remanence curves of strongly interacting fine-particle systems were also investigated theoretically. It was shown that the Henkel plot of the dc demagnetisation remanence vs the isothermal remanence is a useful representation of interactions. The form of the plot was found to be a reflection of the magnetic and physical microstructure of the material, which is consistent with experimental data. The relationship between the Henkel plot and the noise of a particulate recording medium, another property dependent on the microstructure, is also considered. The Interaction Field Factor (IFF), a single parameter characterising the non-linearity of the Henkel plot, is investigated. These results are consistent with a previous experimental study. Finally the results of the noise power spectral density for erased and saturated recording media are presented, so that characterisation of interparticle interactions may be carried out with greater accuracy.

  10. A Microbial Perspective on the Grand Challenges in Comparative Animal Physiology

    Science.gov (United States)

    2018-01-01

    ABSTRACT Interactions with microbial communities can have profound influences on animal physiology, thereby impacting animal performance and fitness. Therefore, it is important to understand the diversity and nature of host-microbe interactions in various animal groups (invertebrates, fish, amphibians, reptiles, birds, and mammals). In this perspective, I discuss how the field of host-microbe interactions can be used to address topics that have been identified as grand challenges in comparative animal physiology: (i) horizontal integration of physiological processes across organisms, (ii) vertical integration of physiological processes across organizational levels within organisms, and (iii) temporal integration of physiological processes during evolutionary change. Addressing these challenges will require the use of a variety of animal models and the development of systems approaches that can integrate large, multiomic data sets from both microbial communities and animal hosts. Integrating host-microbe interactions into the established field of comparative physiology represents an exciting frontier for both fields. PMID:29556549

  11. Systems pharmacology - Towards the modeling of network interactions.

    Science.gov (United States)

    Danhof, Meindert

    2016-10-30

    Mechanism-based pharmacokinetic and pharmacodynamics (PKPD) and disease system (DS) models have been introduced in drug discovery and development research, to predict in a quantitative manner the effect of drug treatment in vivo in health and disease. This requires consideration of several fundamental properties of biological systems behavior including: hysteresis, non-linearity, variability, interdependency, convergence, resilience, and multi-stationarity. Classical physiology-based PKPD models consider linear transduction pathways, connecting processes on the causal path between drug administration and effect, as the basis of drug action. Depending on the drug and its biological target, such models may contain expressions to characterize i) the disposition and the target site distribution kinetics of the drug under investigation, ii) the kinetics of target binding and activation and iii) the kinetics of transduction. When connected to physiology-based DS models, PKPD models can characterize the effect on disease progression in a mechanistic manner. These models have been found useful to characterize hysteresis and non-linearity, yet they fail to explain the effects of the other fundamental properties of biological systems behavior. Recently systems pharmacology has been introduced as novel approach to predict in vivo drug effects, in which biological networks rather than single transduction pathways are considered as the basis of drug action and disease progression. These models contain expressions to characterize the functional interactions within a biological network. Such interactions are relevant when drugs act at multiple targets in the network or when homeostatic feedback mechanisms are operative. As a result systems pharmacology models are particularly useful to describe complex patterns of drug action (i.e. synergy, oscillatory behavior) and disease progression (i.e. episodic disorders). In this contribution it is shown how physiology-based PKPD and

  12. Interactive physically-based structural modeling of hydrocarbon systems

    International Nuclear Information System (INIS)

    Bosson, Mael; Grudinin, Sergei; Bouju, Xavier; Redon, Stephane

    2012-01-01

    Hydrocarbon systems have been intensively studied via numerical methods, including electronic structure computations, molecular dynamics and Monte Carlo simulations. Typically, these methods require an initial structural model (atomic positions and types, topology, etc.) that may be produced using scripts and/or modeling tools. For many systems, however, these building methods may be ineffective, as the user may have to specify the positions of numerous atoms while maintaining structural plausibility. In this paper, we present an interactive physically-based modeling tool to construct structural models of hydrocarbon systems. As the user edits the geometry of the system, atomic positions are also influenced by the Brenner potential, a well-known bond-order reactive potential. In order to be able to interactively edit systems containing numerous atoms, we introduce a new adaptive simulation algorithm, as well as a novel algorithm to incrementally update the forces and the total potential energy based on the list of updated relative atomic positions. The computational cost of the adaptive simulation algorithm depends on user-defined error thresholds, and our potential update algorithm depends linearly with the number of updated bonds. This allows us to enable efficient physically-based editing, since the computational cost is decoupled from the number of atoms in the system. We show that our approach may be used to effectively build realistic models of hydrocarbon structures that would be difficult or impossible to produce using other tools.

  13. An Interactive Astronaut-Robot System with Gesture Control

    Directory of Open Access Journals (Sweden)

    Jinguo Liu

    2016-01-01

    Full Text Available Human-robot interaction (HRI plays an important role in future planetary exploration mission, where astronauts with extravehicular activities (EVA have to communicate with robot assistants by speech-type or gesture-type user interfaces embedded in their space suits. This paper presents an interactive astronaut-robot system integrating a data-glove with a space suit for the astronaut to use hand gestures to control a snake-like robot. Support vector machine (SVM is employed to recognize hand gestures and particle swarm optimization (PSO algorithm is used to optimize the parameters of SVM to further improve its recognition accuracy. Various hand gestures from American Sign Language (ASL have been selected and used to test and validate the performance of the proposed system.

  14. The hard-sphere model of strongly interacting fermion systems

    OpenAIRE

    Mecca, Angela

    2016-01-01

    The formalism based on Correlated Basis Functions (CBF) and the cluster-expansion technique has been recently employed to derive an effective interaction from a realistic nuclear Hamiltonian. One of the main objectives of the work described in this Thesis is establishing the accuracy of this novel approach--that allows to combine the flexibility of perturbation theory in the basis of eigenstates of the noninteracting system with a realistic description of short-range correlations in coordinat...

  15. Music Conductor Gesture Recognized Interactive Music Generation System

    OpenAIRE

    CHEN, Shuai; MAEDA, Yoichiro; TAKAHASHI, Yasutake

    2012-01-01

    In the research of interactive music generation, we propose a music generation method, that the computer generates the music automatically, and then the music will be arranged under the human music conductor's gestures, before it outputs to us. In this research, the generated music is processed from chaotic sound, which is generated from the network of chaotic elements in realtime. The music conductor's hand motions are detected by Microsoft Kinect in this system. Music theories are embedded ...

  16. Ionic interactions in biological and physical systems: a variational treatment.

    Science.gov (United States)

    Eisenberg, Bob

    2013-01-01

    Chemistry is about chemical reactions. Chemistry is about electrons changing their configurations as atoms and molecules react. Chemistry has for more than a century studied reactions as if they occurred in ideal conditions of infinitely dilute solutions. But most reactions occur in salt solutions that are not ideal. In those solutions everything (charged) interacts with everything else (charged) through the electric field, which is short and long range extending to the boundaries of the system. Mathematics has recently been developed to deal with interacting systems of this sort. The variational theory of complex fluids has spawned the theory of liquid crystals (or vice versa). In my view, ionic solutions should be viewed as complex fluids, particularly in the biological and engineering context. In both biology and electrochemistry ionic solutions are mixtures highly concentrated (to approximately 10 M) where they are most important, near electrodes, nucleic ids, proteins, active sites of enzymes, and ionic channels. Ca2+ is always involved in biological solutions because the concentration (really free energy per mole) of Ca2+ in a particular location is the signal that controls many biological functions. Such interacting systems are not simple fluids, and it is no wonder that analysis of interactions, such as the Hofmeister series, rooted in that tradition has not succeeded as one would hope. Here, we present a variational treatment of ard spheres in a frictional dielectric with the hope that such a treatment of an lectrolyte as a complex fluid will be productive. The theory automatically extends to spatially nonuniform boundary conditions and the nonequilibrium systems and flows they produce. The theory is unavoidably self-consistent since differential equations are derived (not assumed) from models of (Helmholtz free) nergy and dissipation of the electrolyte. The origin of the Hofmeister series is (in my view) an inverse problem that becomes well posed when

  17. Unstable system with Coulomb interaction distorted near the origin

    International Nuclear Information System (INIS)

    Kerbikov, B.O.

    1981-01-01

    An unstable system with Coulomb interaction distorted at small distances is considered. The results are applicable to hadronic atoms analysis. A detailed investigation of the model which can be solved exactly is presented. This model contains the separable short-range potential with the Yamaguchi form factor. Closed expressions for the modified effective range function and the Coulomb-modified scattering length ase obtained [ru

  18. Formulations of the closed-shell interactions in endohedral systems

    Czech Academy of Sciences Publication Activity Database

    Wang, C.; Straka, Michal; Pyykkö, P.

    2010-01-01

    Roč. 12, č. 23 (2010), s. 6187-6203 ISSN 1463-9076 R&D Projects: GA ČR GA203/09/2037 Grant - others:7th Framework Program(XE) 230955 Institutional research plan: CEZ:AV0Z40550506 Keywords : endohedral systems * closed-shell interactions * one-center expansion Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 3.454, year: 2010

  19. Numerical Cerebrospinal System Modeling in Fluid-Structure Interaction.

    Science.gov (United States)

    Garnotel, Simon; Salmon, Stéphanie; Balédent, Olivier

    2018-01-01

    Cerebrospinal fluid (CSF) stroke volume in the aqueduct is widely used to evaluate CSF dynamics disorders. In a healthy population, aqueduct stroke volume represents around 10% of the spinal stroke volume while intracranial subarachnoid space stroke volume represents 90%. The amplitude of the CSF oscillations through the different compartments of the cerebrospinal system is a function of the geometry and the compliances of each compartment, but we suspect that it could also be impacted be the cardiac cycle frequency. To study this CSF distribution, we have developed a numerical model of the cerebrospinal system taking into account cerebral ventricles, intracranial subarachnoid spaces, spinal canal and brain tissue in fluid-structure interactions. A numerical fluid-structure interaction model is implemented using a finite-element method library to model the cerebrospinal system and its interaction with the brain based on fluid mechanics equations and linear elasticity equations coupled in a monolithic formulation. The model geometry, simplified in a first approach, is designed in accordance with realistic volume ratios of the different compartments: a thin tube is used to mimic the high flow resistance of the aqueduct. CSF velocity and pressure and brain displacements are obtained as simulation results, and CSF flow and stroke volume are calculated from these results. Simulation results show a significant variability of aqueduct stroke volume and intracranial subarachnoid space stroke volume in the physiological range of cardiac frequencies. Fluid-structure interactions are numerous in the cerebrospinal system and difficult to understand in the rigid skull. The presented model highlights significant variations of stroke volumes under cardiac frequency variations only.

  20. Giant spin torque in systems with anisotropic exchange interaction

    OpenAIRE

    Korenev, Vladimir L.

    2012-01-01

    Control of magnetic domain wall movement by the spin-polarized current looks promising for creation of a new generation of magnetic memory devices. A necessary condition for this is the domain wall shift by a low-density current. Here I show that a strongly anisotropic exchange interaction between mobile heavy holes and localized magnetic moments enormously increases the current-induced torque on the domain wall as compared to systems with isotropic exchange. This enables one to control the d...

  1. Logic of non-interacting programs and reactive systems

    OpenAIRE

    Shelekhov, Vladimir; Tumurov, Erdem

    2012-01-01

    The notion of a program logic is introduced to denote a set of predicates which are true in different program points. The program logic can be easily constructed for different kinds of statements of an imperative or a functional language with data types except pointers. For a non-interacting program, a total correctness formula based on the program logic is defined. The rules of program correctness proof have been developed for proving the statements of various kinds. For a reactive system, t...

  2. Bioaerosols in the Earth system: Climate, health, and ecosystem interactions

    Energy Technology Data Exchange (ETDEWEB)

    Fröhlich-Nowoisky, Janine; Kampf, Christopher J.; Weber, Bettina; Huffman, J. Alex; Pöhlker, Christopher; Andreae, Meinrat O.; Lang-Yona, Naama; Burrows, Susannah M.; Gunthe, Sachin S.; Elbert, Wolfgang; Su, Hang; Hoor, Peter; Thines, Eckhard; Hoffmann, Thorsten; Després, Viviane R.; Pöschl, Ulrich

    2016-12-01

    Aerosols of biological origin play a vital role in the Earth system, particularly in the in-teractions between atmosphere, biosphere, climate, and public health. Airborne bacteria, fungal spores, pollen, and other bioparticles are essential for the reproduction and spread of organisms across various ecosystems, and they can cause or enhance human, animal, and plant diseases. Moreover, they can serve as nuclei for cloud droplets, ice crystals, and precipitation, thus influencing the hydrological cycle and climate. The actual formation, abundance, composition, and effects of biological aerosols and the atmospheric microbi-ome are, however, not yet well characterized and constitute a large gap in the scientific understanding of the interaction and co-evolution of life and climate in the Earth system. This review presents an overview of the state of bioaerosol research and highlights recent advances in terms of bioaerosol identification, characterization, transport, and transfor-mation processes, as well as their interactions with climate, health, and ecosystems, focus-ing on the role bioaerosols play in the Earth system.

  3. Stable propagation of interacting crack systems and modeling of damage

    International Nuclear Information System (INIS)

    Bazant, Z.P.; Tabbara, M.R.

    1989-01-01

    This paper presents general thermodynamic criteria for the stable states and stable path of structures with an interacting system of cracks. In combination with numerical finite element results for various cracked structure geometries, these criteria indicate that the crack response path of structures may exhibit bifurcations, after which the symmetry of the crack system is broken and some cracks grow preferentially. The problem is of interest for the prediction of ultimate loads, ductility and energy absorption capability of nuclear concrete structures as well as structures made of composites and ceramics

  4. An Interactive System For Fourier Analysis Of Artichoke Flower Shape.

    Science.gov (United States)

    Impedovo, Sebastiano; Fanelli, Anna M.; Ligouras, Panagiotis

    1984-06-01

    In this paper we present an interactive system which allows the Fourier analysis of the artichoke flower-head profile. The system consistsof a DEC pdp 11/34 computer with both a a track-following device and a Tektronix 4010/1 graphic and alpha numeric display on-line. Some experiments have been carried out taking into account some different parental types of artichoke flower-head samples. It is shown here that a narrow band of only eight harmonics is sufficient to classify different artichoke flower shapes.

  5. Fault Diagnosis in Dynamic Systems Using Fuzzy Interacting Observers

    Directory of Open Access Journals (Sweden)

    N. V. Kolesov

    2013-01-01

    Full Text Available A method of fault diagnosis in dynamic systems based on a fuzzy approach is proposed. The new method possesses two basic specific features which distinguish it from the other known fuzzy methods based on the application of fuzzy logic and a bank of state observers. First, this method uses a bank of interacting observers instead of traditional independent observers. The second specific feature of the proposed method is the assumption that there is no strict boundary between the serviceable and disabled technical states of the system, which makes it possible to specify a decision making rule for fault diagnosis.

  6. Intelligent adaptive systems an interaction-centered design perspective

    CERN Document Server

    Hou, Ming; Burns, Catherine

    2014-01-01

    A synthesis of recent research and developments on intelligent adaptive systems from the HF (human factors) and HCI (human-computer interaction) domains, this book provides integrated design guidance and recommendations for researchers and system developers. It addresses a recognized lack of integration between the HF and HCI research communities, which has led to inconsistencies between the research approaches adopted, and a lack of exploitation of research from one field by the other. The book establishes design guidance through the review of conceptual frameworks, analytical methodologies,

  7. Utilizing media arts principles for developing effective interactive neurorehabilitation systems.

    Science.gov (United States)

    Rikakis, Thanassis

    2011-01-01

    This paper discusses how interactive neurorehabilitation systems can increase their effectiveness through systematic integration of media arts principles and practice. Media arts expertise can foster the development of complex yet intuitive extrinsic feedback displays that match the inherent complexity and intuitive nature of motor learning. Abstract, arts-based feedback displays can be powerful metaphors that provide re-contextualization, engagement and appropriate reward mechanisms for mature adults. Such virtual feedback displays must be seamlessly integrated with physical components to produce mixed reality training environments that promote active, generalizable learning. The proposed approaches are illustrated through examples from mixed reality rehabilitation systems developed by our team.

  8. Advanced and natural interaction system for motion-impaired users

    OpenAIRE

    Manresa Yee, Cristina Suemay

    2009-01-01

    Human-computer interaction is an important area that searches for better and more comfortable systems to promote communication between humans and machines. Vision-based interfaces can offer a more natural and appealing way of communication. Moreover, it can help in the e-accessibility component of the e-inclusion. The aim is to develop a usable system, that is, the end-user must consider the use of this device effective, efficient and satisfactory. The research's main contribution is SINA, a ...

  9. Implementation of an interactive liver surgery planning system

    Science.gov (United States)

    Wang, Luyao; Liu, Jingjing; Yuan, Rong; Gu, Shuguo; Yu, Long; Li, Zhitao; Li, Yanzhao; Li, Zhen; Xie, Qingguo; Hu, Daoyu

    2011-03-01

    Liver tumor, one of the most wide-spread diseases, has a very high mortality in China. To improve success rates of liver surgeries and life qualities of such patients, we implement an interactive liver surgery planning system based on contrastenhanced liver CT images. The system consists of five modules: pre-processing, segmentation, modeling, quantitative analysis and surgery simulation. The Graph Cuts method is utilized to automatically segment the liver based on an anatomical prior knowledge that liver is the biggest organ and has almost homogeneous gray value. The system supports users to build patient-specific liver segment and sub-segment models using interactive portal vein branch labeling, and to perform anatomical resection simulation. It also provides several tools to simulate atypical resection, including resection plane, sphere and curved surface. To match actual surgery resections well and simulate the process flexibly, we extend our work to develop a virtual scalpel model and simulate the scalpel movement in the hepatic tissue using multi-plane continuous resection. In addition, the quantitative analysis module makes it possible to assess the risk of a liver surgery. The preliminary results show that the system has the potential to offer an accurate 3D delineation of the liver anatomy, as well as the tumors' location in relation to vessels, and to facilitate liver resection surgeries. Furthermore, we are testing the system in a full-scale clinical trial.

  10. Flooring-systems and their interaction with furniture and humans

    DEFF Research Database (Denmark)

    Frier, Christian; Pedersen, Lars; Andersen, Lars Vabbersgaard

    2017-01-01

    Flooring-system designs may be sensitive in terms of their vibrational performance due the risk that serviceability-limit-state problems may be encountered. For evaluating the vibrational performance of a flooring system at the design stage, decisions must be made by the engineer in charge...... of computations. Passive humans and/or furniture are often present on a floor. Typically, these masses and their way of interacting with the floor mass are ignored in predictions of vibrational behaviour of the flooring system. Utilizing a shell finite-element model, the paper explores and quantifies how non......-structural mass can influence central parameters describing the dynamic behaviour of the flooring system with focus on elevated non-structural mass. © 2017 The Authors. Published by Elsevier Ltd....

  11. Statistics in a Trilinear Interacting Stokes-Antistokes Boson System

    Science.gov (United States)

    Tänzler, W.; Schütte, F.-J.

    The statistics of a system of four boson modes is treated with simultaneous Stokes-Antistokes interaction taking place. The time evolution is calculated in full quantum manner but in short time approximation. Mean photon numbers and correlations of second order are calculated. Antibunching can be found in the laser mode and in the system of Stokes and Antistokes mode.Translated AbstractStatistik in einem trilinear wechselwirkenden Stokes-Antistokes-BosonensystemDie Statistik eines Systems von vier Bosonenmoden mit gleichzeitiger Stokes-Antistokes-Wechselwirkung wird bei vollquantenphysikalischer Beschreibung in Kurzzeitnäherung untersucht. Mittlere Photonenzahlen und Korrelationen zweiter Ordnung werden berechnet. Dabei wird Antibunching sowohl in der Lasermode allein als auch im System aus Stokes- und Antistokesmode gefunden.

  12. Sikorsky interactive graphics surface design/manufacturing system

    Science.gov (United States)

    Robbins, R.

    1975-01-01

    An interactive graphics system conceived to be used in the design, analysis, and manufacturing of aircraft components with free form surfaces was described. In addition to the basic surface definition and viewing capabilities inherent in such a system, numerous other features are present: surface editing, automated smoothing of control curves, variable milling patch boundary definitions, surface intersection definition and viewing, automatic creation of true offset surfaces, digitizer and drafting machine interfaces, and cutter path optimization. Documented costs and time savings of better than six to one are being realized with this system. The system was written in FORTRAN and GSP for use on IBM 2250 CRT's in conjunction with an IBM 370/158 computer.

  13. MINDS: A microcomputer interactive data system for 8086-based controllers

    Science.gov (United States)

    Soeder, J. F.

    1985-01-01

    A microcomputer interactive data system (MINDS) software package for the 8086 family of microcomputers is described. To enhance program understandability and ease of code maintenance, the software is written in PL/M-86, Intel Corporation's high-level system implementation language. The MINDS software is intended to run in residence with real-time digital control software to provide displays of steady-state and transient data. In addition, the MINDS package provides classic monitor capabilities along with extended provisions for debugging an executing control system. The software uses the CP/M-86 operating system developed by Digital Research, Inc., to provide program load capabilities along with a uniform file structure for data and table storage. Finally, a library of input and output subroutines to be used with consoles equipped with PL/M-86 and assembly language is described.

  14. A Multimodal Emotion Detection System during Human-Robot Interaction

    Science.gov (United States)

    Alonso-Martín, Fernando; Malfaz, María; Sequeira, João; Gorostiza, Javier F.; Salichs, Miguel A.

    2013-01-01

    In this paper, a multimodal user-emotion detection system for social robots is presented. This system is intended to be used during human–robot interaction, and it is integrated as part of the overall interaction system of the robot: the Robotics Dialog System (RDS). Two modes are used to detect emotions: the voice and face expression analysis. In order to analyze the voice of the user, a new component has been developed: Gender and Emotion Voice Analysis (GEVA), which is written using the Chuck language. For emotion detection in facial expressions, the system, Gender and Emotion Facial Analysis (GEFA), has been also developed. This last system integrates two third-party solutions: Sophisticated High-speed Object Recognition Engine (SHORE) and Computer Expression Recognition Toolbox (CERT). Once these new components (GEVA and GEFA) give their results, a decision rule is applied in order to combine the information given by both of them. The result of this rule, the detected emotion, is integrated into the dialog system through communicative acts. Hence, each communicative act gives, among other things, the detected emotion of the user to the RDS so it can adapt its strategy in order to get a greater satisfaction degree during the human–robot dialog. Each of the new components, GEVA and GEFA, can also be used individually. Moreover, they are integrated with the robotic control platform ROS (Robot Operating System). Several experiments with real users were performed to determine the accuracy of each component and to set the final decision rule. The results obtained from applying this decision rule in these experiments show a high success rate in automatic user emotion recognition, improving the results given by the two information channels (audio and visual) separately. PMID:24240598

  15. Protein- protein interaction detection system using fluorescent protein microdomains

    Science.gov (United States)

    Waldo, Geoffrey S.; Cabantous, Stephanie

    2010-02-23

    The invention provides a protein labeling and interaction detection system based on engineered fragments of fluorescent and chromophoric proteins that require fused interacting polypeptides to drive the association of the fragments, and further are soluble and stable, and do not change the solubility of polypeptides to which they are fused. In one embodiment, a test protein X is fused to a sixteen amino acid fragment of GFP (.beta.-strand 10, amino acids 198-214), engineered to not perturb fusion protein solubility. A second test protein Y is fused to a sixteen amino acid fragment of GFP (.beta.-strand 11, amino acids 215-230), engineered to not perturb fusion protein solubility. When X and Y interact, they bring the GFP strands into proximity, and are detected by complementation with a third GFP fragment consisting of GFP amino acids 1-198 (strands 1-9). When GFP strands 10 and 11 are held together by interaction of protein X and Y, they spontaneous association with GFP strands 1-9, resulting in structural complementation, folding, and concomitant GFP fluorescence.

  16. The Electron-Phonon Interaction in Strongly Correlated Systems

    International Nuclear Information System (INIS)

    Castellani, C.; Grilli, M.

    1995-01-01

    We analyze the effect of strong electron-electron repulsion on the electron-phonon interaction from a Fermi-liquid point of view and show that the electron-electron interaction is responsible for vertex corrections, which generically lead to a strong suppression of the electron-phonon coupling in the v F q/ω >>1 region, while such effect is not present when v F q/ω F is the Fermi velocity and q and ω are the transferred momentum and frequency respectively. In particular the e-ph scattering is suppressed in transport properties which are dominated by low-energy-high-momentum processes. On the other hand, analyzing the stability criterion for the compressibility, which involves the effective interactions in the dynamical limit, we show that a sizable electron-phonon interaction can push the system towards a phase-separation instability. Finally a detailed analysis of these ideas is carried out using a slave-boson approach for the infinite-U three-band Hubbard model in the presence of a coupling between the local hole density and a dispersionless optical phonon. (author)

  17. Effects of an electric field on interaction of aromatic systems.

    Science.gov (United States)

    Youn, Il Seung; Cho, Woo Jong; Kim, Kwang S

    2016-04-30

    The effect of uniform external electric field on the interactions between small aromatic compounds and an argon atom is investigated using post-HF (MP2, SCS-MP2, and CCSD(T)) and density functional (PBE0-D3, PBE0-TS, and vdW-DF2) methods. The electric field effect is quantified by the difference of interaction energy calculated in the presence and absence of the electric field. All the post-HF methods describe electric field effects accurately although the interaction energy itself is overestimated by MP2. The electric field effect is explained by classical electrostatic models, where the permanent dipole moment from mutual polarization mainly determines its sign. The size of π-conjugated system does not have significant effect on the electric field dependence. We found out that PBE0-based methods give reasonable interaction energies and electric field response in every case, while vdW-DF2 sometimes shows spurious artifact owing to its sensitivity toward the real space electron density. © 2015 Wiley Periodicals, Inc.

  18. Response functions for infinite fermion systems with velocity dependent interactions

    International Nuclear Information System (INIS)

    Garcia-Recio, C.; Salcedo, L.L.; Navarro, J.; Nguyen Van Giai

    1991-01-01

    Response functions of infinite Fermi systems are studied in the framework of the self-consistent Random Phase Approximation. Starting from an effective interaction with velocity and density dependence, or equivalently from a local energy density functional, algebraic expressions for the RPA response function are derived. Simple formulae for the energy-weighted and polarizability sum rules are obtained. The method is illustrated by applications to nuclear matter and liquid 3 He. In nuclear matter, it is shown that existing Skyrme interactions give spin-isospin response functions close to those calculated with finite range interactions. The different renormalization of longitudinal and transverse Coulomb sum rules in nuclear matter is discussed. In 3 He, the low-lying collective spin oscillation can be well described in a wide range of momenta with a Skyrme-type interaction if the relevant Landau parameters are fitted. For the high-lying density oscillation, the introduction of a finite range term in the energy functional improves considerably the agreement with the data. (author) 54 refs., 19 figs., 4 tabs

  19. Tactile interactions activate mirror system regions in the human brain.

    Science.gov (United States)

    McKyton, Ayelet

    2011-12-07

    Communicating with others is essential for the development of a society. Although types of communications, such as language and visual gestures, were thoroughly investigated in the past, little research has been done to investigate interactions through touch. To study this we used functional magnetic resonance imaging. Twelve participants were scanned with their eyes covered while stroking four kinds of items, representing different somatosensory stimuli: a human hand, a realistic rubber hand, an object, and a simple texture. Although the human and the rubber hands had the same overall shape, in three regions there was significantly more blood oxygen level dependent activation when touching the real hand: the anterior medial prefrontal cortex, the ventral premotor cortex, and the posterior superior temporal cortex. The last two regions are part of the mirror network and are known to be activated through visual interactions such as gestures. Interestingly, in this study, these areas were activated through a somatosensory interaction. A control experiment was performed to eliminate confounds of temperature, texture, and imagery, suggesting that the activation in these areas was correlated with the touch of a human hand. These results reveal the neuronal network working behind human tactile interactions, and highlight the participation of the mirror system in such functions.

  20. SIDAS - a block-diagram programming system for the interactive digital simulation of dynamic systems

    International Nuclear Information System (INIS)

    Moll, H.; Burkhardt, H.

    1978-01-01

    The paper describes a block-oriented digital simulation system. Some applications clarify the basic structure and operation. The main features of the system are: Easy handling and manipulation through interactive graphical input/output, operational flexibility through successive simulation runs and online modification of parameters, direct access to all facilities of a medium-sized computing system. (orig.) [de

  1. An Interactive Personalized Recommendation System Using the Hybrid Algorithm Model

    Directory of Open Access Journals (Sweden)

    Yan Guo

    2017-10-01

    Full Text Available With the rapid development of e-commerce, the contradiction between the disorder of business information and customer demand is increasingly prominent. This study aims to make e-commerce shopping more convenient, and avoid information overload, by an interactive personalized recommendation system using the hybrid algorithm model. The proposed model first uses various recommendation algorithms to get a list of original recommendation results. Combined with the customer’s feedback in an interactive manner, it then establishes the weights of corresponding recommendation algorithms. Finally, the synthetic formula of evidence theory is used to fuse the original results to obtain the final recommendation products. The recommendation performance of the proposed method is compared with that of traditional methods. The results of the experimental study through a Taobao online dress shop clearly show that the proposed method increases the efficiency of data mining in the consumer coverage, the consumer discovery accuracy and the recommendation recall. The hybrid recommendation algorithm complements the advantages of the existing recommendation algorithms in data mining. The interactive assigned-weight method meets consumer demand better and solves the problem of information overload. Meanwhile, our study offers important implications for e-commerce platform providers regarding the design of product recommendation systems.

  2. Mechanical Interaction in Pressurized Pipe Systems: Experiments and Numerical Models

    Directory of Open Access Journals (Sweden)

    Mariana Simão

    2015-11-01

    Full Text Available The dynamic interaction between the unsteady flow occurrence and the resulting vibration of the pipe are analyzed based on experiments and numerical models. Waterhammer, structural dynamic and fluid–structure interaction (FSI are the main subjects dealt with in this study. Firstly, a 1D model is developed based on the method of characteristics (MOC using specific damping coefficients for initial components associated with rheological pipe material behavior, structural and fluid deformation, and type of anchored structural supports. Secondly a 3D coupled complex model based on Computational Fluid Dynamics (CFD, using a Finite Element Method (FEM, is also applied to predict and distinguish the FSI events. Herein, a specific hydrodynamic model of viscosity to replicate the operation of a valve was also developed to minimize the number of mesh elements and the complexity of the system. The importance of integrated analysis of fluid–structure interaction, especially in non-rigidity anchored pipe systems, is equally emphasized. The developed models are validated through experimental tests.

  3. Interacting particle systems in time-dependent geometries

    Science.gov (United States)

    Ali, A.; Ball, R. C.; Grosskinsky, S.; Somfai, E.

    2013-09-01

    Many complex structures and stochastic patterns emerge from simple kinetic rules and local interactions, and are governed by scale invariance properties in combination with effects of the global geometry. We consider systems that can be described effectively by space-time trajectories of interacting particles, such as domain boundaries in two-dimensional growth or river networks. We study trajectories embedded in time-dependent geometries, and the main focus is on uniformly expanding or decreasing domains for which we obtain an exact mapping to simple fixed domain systems while preserving the local scale invariance properties. This approach was recently introduced in Ali et al (2013 Phys. Rev. E 87 020102(R)) and here we provide a detailed discussion on its applicability for self-affine Markovian models, and how it can be adapted to self-affine models with memory or explicit time dependence. The mapping corresponds to a nonlinear time transformation which converges to a finite value for a large class of trajectories, enabling an exact analysis of asymptotic properties in expanding domains. We further provide a detailed discussion of different particle interactions and generalized geometries. All our findings are based on exact computations and are illustrated numerically for various examples, including Lévy processes and fractional Brownian motion.

  4. Modulating bacterial and gut mucosal interactions with engineered biofilm matrix proteins.

    Science.gov (United States)

    Duraj-Thatte, Anna M; Praveschotinunt, Pichet; Nash, Trevor R; Ward, Frederick R; Joshi, Neel S

    2018-02-22

    Extracellular appendages play a significant role in mediating communication between bacteria and their host. Curli fibers are a class of bacterial fimbria that is highly amenable to engineering. We demonstrate the use of engineered curli fibers to rationally program interactions between bacteria and components of the mucosal epithelium. Commensal E. coli strains were engineered to produce recombinant curli fibers fused to the trefoil family of human cytokines. Biofilms formed from these strains bound more mucins than those producing wild-type curli fibers, and modulated mucin rheology as well. When treated with bacteria producing the curli-trefoil fusions mammalian cells behaved identically in terms of their migration behavior as when they were treated with the corresponding soluble trefoil factors. Overall, this demonstrates the potential utility of curli fibers as a scaffold for the display of bioactive domains and an untapped approach to rationally modulating host-microbe interactions using bacterial matrix proteins.

  5. Quantum uncertainty in critical systems with three spins interaction

    International Nuclear Information System (INIS)

    Carrijo, Thiago M; Avelar, Ardiley T; Céleri, Lucas C

    2015-01-01

    In this article we consider two spin-1/2 chains described, respectively, by the thermodynamic limit of the XY model with the usual two site interaction, and an extension of this model (without taking the thermodynamics limit), called XYT, were a three site interaction term is presented. To investigate the critical behaviour of such systems we employ tools from quantum information theory. Specifically, we show that the local quantum uncertainty, a quantity introduced in order to quantify the minimum quantum share of the variance of a local measurement, can be used to indicate quantum phase transitions presented by these models at zero temperature. Due to the connection of this quantity with the quantum Fisher information, the results presented here may be relevant for quantum metrology and quantum thermodynamics. (paper)

  6. Long lifetimes of ultrahot particles in interacting Fermi systems

    Science.gov (United States)

    Bard, M.; Protopopov, I. V.; Mirlin, A. D.

    2018-05-01

    The energy dependence of the relaxation rate of hot electrons due to interaction with the Fermi sea is studied. We consider 2D and 3D systems, quasi-1D quantum wires with multiple transverse bands, as well as single-channel 1D wires. Our analysis includes both spinful and spin-polarized setups, with short-range and Coulomb interactions. We show that, quite generally, the relaxation rate is a nonmonotonic function of the electron energy and decays as a power law at high energies. In other words, ultrahot electrons regain their coherence with increasing energy. Such a behavior was observed in a recent experiment on multiband quantum wires, J. Reiner et al., Phys. Rev. X 7, 021016 (2017)., 10.1103/PhysRevX.7.021016

  7. Exchange interactions in two-state systems: rare earth pyrochlores

    Science.gov (United States)

    Curnoe, S. H.

    2018-06-01

    The general form of the nearest neighbour exchange interaction for rare earth pyrochlores is derived based on symmetry. Generally, the rare earth angular momentum degeneracy is lifted by the crystal electric field (CEF) into singlets and doublets. When the CEF ground state is a doublet that is well-separated from the first excited state the CEF ground state doublet can be treated as a pseudo-spin of some kind. The general form of the nearest neighbour exchange interaction for pseudo-spins on the pyrochlore lattice is derived for three different types of pseudo-spins. The methodology presented in this paper can be applied to other two-state spin systems with a high space group symmetry.

  8. Developing an interactive intervention planner: a systems engineering perspective

    CERN Document Server

    Fabry, Thomas; Feral, Bruno; Braesch, Christian

    2013-01-01

    Intervention planning is crucial for maintenance operations in particle accelerator environments with ionizing radiation, during which the radiation dose received by maintenance workers should be reduced to a minimum. In this context, we discuss the development of a new software tool and the entailed methodology, including the visualization aspects. The software tool integrates interactive exploration of a scene depicting an accelerator facility augmented with residual radiation level simulations, with the visualization of intervention data such as the followed trajectory and maintenance tasks. Its conception allows for future inclusion of measurements performed by mobile robotic devices. In this work, we explore the systems engineering life cycle of the development process of an interactive intervention planner, which includes the needs analysis, specification explicitation, conceptual mathematical modelling, iterative implementation, design and prototype testing and usability testing.

  9. Developing an Interactive Intervention Planner - A Systems Engineering Perspective

    Directory of Open Access Journals (Sweden)

    Thomas Fabry

    2013-09-01

    Full Text Available Intervention planning is crucial for maintenance operations in particle accelerator environments with ionizing radiation, during which the radiation dose received by maintenance workers should be reduced to a minimum. In this context, we discuss the development of a new software tool and the entailed methodology, including the visualization aspects. The software tool integrates interactive exploration of a scene depicting an accelerator facility augmented with residual radiation level simulations, with the visualization of intervention data such as the followed trajectory and maintenance tasks. Its conception allows for future inclusion of measurements performed by mobile robotic devices. In this work, we explore the systems engineering life cycle of the development process of an interactive intervention planner, which includes the needs analysis, specification explicitation, conceptual mathematical modelling, iterative implementation, design and prototype testing and usability testing.

  10. Quantum and classical behavior in interacting bosonic systems

    Energy Technology Data Exchange (ETDEWEB)

    Hertzberg, Mark P. [Institute of Cosmology & Department of Physics and Astronomy, Tufts University,Medford, MA 02155 (United States)

    2016-11-21

    It is understood that in free bosonic theories, the classical field theory accurately describes the full quantum theory when the occupancy numbers of systems are very large. However, the situation is less understood in interacting theories, especially on time scales longer than the dynamical relaxation time. Recently there have been claims that the quantum theory deviates spectacularly from the classical theory on this time scale, even if the occupancy numbers are extremely large. Furthermore, it is claimed that the quantum theory quickly thermalizes while the classical theory does not. The evidence for these claims comes from noticing a spectacular difference in the time evolution of expectation values of quantum operators compared to the classical micro-state evolution. If true, this would have dramatic consequences for many important phenomena, including laboratory studies of interacting BECs, dark matter axions, preheating after inflation, etc. In this work we critically examine these claims. We show that in fact the classical theory can describe the quantum behavior in the high occupancy regime, even when interactions are large. The connection is that the expectation values of quantum operators in a single quantum micro-state are approximated by a corresponding classical ensemble average over many classical micro-states. Furthermore, by the ergodic theorem, a classical ensemble average of local fields with statistical translation invariance is the spatial average of a single micro-state. So the correlation functions of the quantum and classical field theories of a single micro-state approximately agree at high occupancy, even in interacting systems. Furthermore, both quantum and classical field theories can thermalize, when appropriate coarse graining is introduced, with the classical case requiring a cutoff on low occupancy UV modes. We discuss applications of our results.

  11. Interacting multiagent systems kinetic equations and Monte Carlo methods

    CERN Document Server

    Pareschi, Lorenzo

    2014-01-01

    The description of emerging collective phenomena and self-organization in systems composed of large numbers of individuals has gained increasing interest from various research communities in biology, ecology, robotics and control theory, as well as sociology and economics. Applied mathematics is concerned with the construction, analysis and interpretation of mathematical models that can shed light on significant problems of the natural sciences as well as our daily lives. To this set of problems belongs the description of the collective behaviours of complex systems composed by a large enough number of individuals. Examples of such systems are interacting agents in a financial market, potential voters during political elections, or groups of animals with a tendency to flock or herd. Among other possible approaches, this book provides a step-by-step introduction to the mathematical modelling based on a mesoscopic description and the construction of efficient simulation algorithms by Monte Carlo methods. The ar...

  12. Interactive graphics analysis system for nuclear engineering applications

    International Nuclear Information System (INIS)

    Danchak, M.; Moyer, W.R.; Becker, M.

    1973-01-01

    From working with continuous slowing down theory, the need was recognized for a system which allowed rapid calculation of the theoretical flux, instant comparison with experiment and a simple means of iterating on the slowing down parameters to force flux agreement and reflect cross section modification. Similar requirements exist in other areas of nuclear work for streamlining and simplifying the data analysis process. As a solution, a unique interactive graphics analysis system (RIGAS) was devised to allow a user to calculate, display, compare, manipulate and modify his data without requiring any programming on his part. This was accomplished by establishing human primacy, through extensive human factor considerations, and designing a man-machine dialogue which responds to the mere push of a button. This system results in an instrument which maximizes man's decision making capability and the computer's speed to improve graphic communication and data analysis. (14 figs) (U.S.)

  13. Current understanding of interactions between nanoparticles and the immune system.

    Science.gov (United States)

    Dobrovolskaia, Marina A; Shurin, Michael; Shvedova, Anna A

    2016-05-15

    The delivery of drugs, antigens, and imaging agents benefits from using nanotechnology-based carriers. The successful translation of nanoformulations to the clinic involves thorough assessment of their safety profiles, which, among other end-points, includes evaluation of immunotoxicity. The past decade of research focusing on nanoparticle interaction with the immune system has been fruitful in terms of understanding the basics of nanoparticle immunocompatibility, developing a bioanalytical infrastructure to screen for nanoparticle-mediated immune reactions, beginning to uncover the mechanisms of nanoparticle immunotoxicity, and utilizing current knowledge about the structure-activity relationship between nanoparticles' physicochemical properties and their effects on the immune system to guide safe drug delivery. In the present review, we focus on the most prominent pieces of the nanoparticle-immune system puzzle and discuss the achievements, disappointments, and lessons learned over the past 15years of research on the immunotoxicity of engineered nanomaterials. Copyright © 2016 Elsevier Inc. All rights reserved.

  14. The partition function of an interacting many body system

    International Nuclear Information System (INIS)

    Rummel, C.; Ankerhold, J.

    2002-01-01

    Based on the path integral approach the partition function of a many body system with separable two body interaction is calculated in the sense of a semiclassical approximation. The commonly used Gaussian type of approximation, known as the perturbed static path approximation (PSPA), breaks down near a crossover temperature due to instabilities of the classical mean field solution. It is shown how the PSPA is systematically improved within the crossover region by taking into account large non-Gaussian fluctuation and an approximation applicable down to very low temperatures is carried out. These findings are tested against exact results for the archetypical cases of a particle moving in a one dimensional double well and the exactly solvable Lipkin-Meshkov-Glick model. The extensions should have applications in finite systems at low temperatures as in nuclear physics and mesoscopic systems, e. g. for gap fluctuations in nano-scale superconducting devices previously studied within a PSPA type of approximation. (author)

  15. Arm Motion Recognition and Exercise Coaching System for Remote Interaction

    Directory of Open Access Journals (Sweden)

    Hong Zeng

    2016-01-01

    Full Text Available Arm motion recognition and its related applications have become a promising human computer interaction modal due to the rapid integration of numerical sensors in modern mobile-phones. We implement a mobile-phone-based arm motion recognition and exercise coaching system that can help people carrying mobile-phones to do body exercising anywhere at any time, especially for the persons that have very limited spare time and are constantly traveling across cities. We first design improved k-means algorithm to cluster the collecting 3-axis acceleration and gyroscope data of person actions into basic motions. A learning method based on Hidden Markov Model is then designed to classify and recognize continuous arm motions of both learners and coaches, which also measures the action similarities between the persons. We implement the system on MIUI 2S mobile-phone and evaluate the system performance and its accuracy of recognition.

  16. Software Design for Interactive Graphic Radiation Treatment Simulation Systems*

    Science.gov (United States)

    Kalet, Ira J.; Sweeney, Christine; Jacky, Jonathan

    1990-01-01

    We examine issues in the design of interactive computer graphic simulation programs for radiation treatment planning (RTP), as well as expert system programs that automate parts of the RTP process, in light of ten years of experience at designing, building and using such programs. An experiment in object-oriented design using standard Pascal shows that while some advantage is gained from the design, it is still difficult to achieve modularity and to integrate expert system components. A new design based on the Common LISP Object System (CLOS) is described. This series of designs for RTP software shows that this application benefits in specific ways from object-oriented design methods and appropriate languages and tools.

  17. Interactions in the energy supply system. Mechanisms - interactions - examples. An analysis

    International Nuclear Information System (INIS)

    Ausfelder, Florian; Wagemann, Kurt; Drake, Frank-Detlef; Paschke, Marian; Schueth, Ferdi; Themann, Michael; Wagner, Hermann-Josef

    2015-01-01

    In embarking on the energy turnaround Germany has taken upon itself one of the greatest self-chosen challenges of the future, namely to transform the energy supply system from being predominantly dependent on fossil fuels to relying almost entirely on renewable energy resources. The driving goal behind this project, which has wide public acceptance, is to ensure that our energy supply remains sustainable, safe and affordable. This transformation process by a successful industrial nation is being followed abroad with great interest. The present document does not undertake a political assessment of the energy turnaround or its goals. It rather focuses on an analysis of effects brought about by individual measures on the system as a whole. This systemic view opens up a new perspective on the ''engine room'' of the energy turnaround. It allows one to inquire whether a given measure actually fulfils the expectations that have been placed in it for the system as a whole - expectations that are often born from too narrow a perspective - or whether it is having unexpected, undesirable effects. These can impact on the effectiveness of a specific measure in realising the goals of the energy turnaround. The authors believe that having as precise knowledge as possible of these systemic interactions is a fundamental prerequisite to managing the energy turnaround in such a way that its goals are achieved as effectively and efficiently as possible.

  18. PathSys: integrating molecular interaction graphs for systems biology

    Directory of Open Access Journals (Sweden)

    Raval Alpan

    2006-02-01

    Full Text Available Abstract Background The goal of information integration in systems biology is to combine information from a number of databases and data sets, which are obtained from both high and low throughput experiments, under one data management scheme such that the cumulative information provides greater biological insight than is possible with individual information sources considered separately. Results Here we present PathSys, a graph-based system for creating a combined database of networks of interaction for generating integrated view of biological mechanisms. We used PathSys to integrate over 14 curated and publicly contributed data sources for the budding yeast (S. cerevisiae and Gene Ontology. A number of exploratory questions were formulated as a combination of relational and graph-based queries to the integrated database. Thus, PathSys is a general-purpose, scalable, graph-data warehouse of biological information, complete with a graph manipulation and a query language, a storage mechanism and a generic data-importing mechanism through schema-mapping. Conclusion Results from several test studies demonstrate the effectiveness of the approach in retrieving biologically interesting relations between genes and proteins, the networks connecting them, and of the utility of PathSys as a scalable graph-based warehouse for interaction-network integration and a hypothesis generator system. The PathSys's client software, named BiologicalNetworks, developed for navigation and analyses of molecular networks, is available as a Java Web Start application at http://brak.sdsc.edu/pub/BiologicalNetworks.

  19. Phase transitions in random uniaxial systems with dipolar interactions

    International Nuclear Information System (INIS)

    Schuster, H.G.

    1977-01-01

    The critical behaviour of random uniaxial ferromagnetic (ferroelectric) systems with both short range and long range dipolar interactions is investigated, using the field theoretic renormalization method of Brezin et al. for the free energy above and below transition point Tsub(c). The randomness is due to externally introduced fluctuations in the short range interactions (quenched case) or (and) magneto-elastic coupling to the lattice (annealed case). Strong deviations in the critical behaviour with respect to the pure systems are found. In the quenched case, e.g., the specific heat C and the coefficient f 2 (of M 3 in the equation of state, where M is the magnetization) change from C proportional to abs ln abs t abs abssup(1/3), f 2 proportional to abs ln abs t abs abs sup(1/3), f 2 proportional to abs ln abs t abs abs -1 in the pure system to C = A+- + C+-exp[-4√ 3 106 abs ln abs t abs abs], f 2 proportional to abs ln abs t abs abs sup(-1/2) (where t = (T-Tsub(c)) / Tsub(c) is the reduced temperature and A+-, C+- are constants) in the random situation. (orig.) [de

  20. Effective interactions in strongly-coupled quantum systems

    International Nuclear Information System (INIS)

    Chen, J.M.C.

    1986-01-01

    In this thesis, they study the role of effective interactions in strongly-coupled Fermi systems where the short-range correlations introduce difficulties requiring special treatment. The correlated basis function method provides the means to incorporate the short-range correlations and generate the matrix elements of the Hamiltonian and identity operators in a nonorthogonal basis of states which are so important to their studies. In the first half of the thesis, the particle-hole channel is examined to elucidate the effects of collective excitations. Proceeding from a least-action principle, a generalization of the random-phase approximation is developed capable of describing such strongly-interacting Fermi systems as nuclei, nuclear matter, neutron-star matter, and liquid 3 He. A linear response of dynamically correlated system to a weak external perturbation is also derived based on the same framework. In the second half of the thesis, the particle-particle channel is examined to elucidate the effects of pairing in nuclear and neutron-star matter

  1. An interactive data management and analysis system for clinical investigators.

    Science.gov (United States)

    Groner, G F; Hopwood, M D; Palley, N A; Sibley, W L; Baker, W R; Christopher, T G; Thompson, H K

    1978-09-01

    An interactive minicomputer-based system has been developed that enables the clinical research investigator to personally explore and analyze his research data and, as a consequence of these explorations, to acquire more information. This system, which does not require extensive training or computer programming, enables the investigator to describe his data interactively in his own terms, enter data values while having them checked for validity, store time-oriented patient data in a carefully controlled on-line data base, retrieve data by patient, variable, and time, create subsets of patients with common characteristics, perform statistical analyses, and produce tables and graphs. It also permits data to be transferred to and from other computers. The system is well accepted and is being used by a variety of medical specialists at the three clinical research centers where it is operational. Reported benefits include less elapsed and nonproductive time, more thorough analysis of more data, greater and earlier insight into the meaning of research data, and increased publishable results.

  2. The functional renormalization group for interacting quantum systems with spin-orbit interaction

    International Nuclear Information System (INIS)

    Grap, Stephan Michael

    2013-01-01

    We studied the influence of spin-orbit interaction (SOI) in interacting low dimensional quantum systems at zero temperature within the framework of the functional renormalization group (fRG). Among the several types of spin-orbit interaction the so-called Rashba spin-orbit interaction is especially intriguing for future spintronic applications as it may be tuned via external electric fields. We investigated its effect on the low energy physics of an interacting quantum wire in an applied Zeeman field which is modeled as a generalization of the extended Hubbard model. To this end we performed a renormalization group study of the two particle interaction, including the SOI and the Zeeman field exactly on the single particle level. Considering the resulting two band model, we formulated the RG equations for the two particle vertex keeping the full band structure as well as the non trivial momentum dependence of the low energy two particle scattering processes. In order to solve these equations numerically we defined criteria that allowed us to classify whether a given set of initial conditions flows towards the strongly coupled regime. We found regions in the models parameter space where a weak coupling method as the fRG is applicable and it is possible to calculate additional quantities of interest. Furthermore we analyzed the effect of the Rashba SOI on the properties of an interacting multi level quantum dot coupled to two semi in nite leads. Of special interest was the interplay with a Zeeman field and its orientation with respect to the SOI term. We found a renormalization of the spin-orbit energy which is an experimental quantity used to asses SOI effects in transport measurements, as well as renormalized effective g factors used to describe the Zeeman field dependence. In particular in asymmetrically coupled systems the large parameter space allows for rich physics which we studied by means of the linear conductance obtained via the generalized Landauer

  3. The kaon factory - towards the physics of strongly interacting systems

    International Nuclear Information System (INIS)

    Vogt, Erich

    1988-01-01

    With the advent of the standard model for quarks and leptons and unified forces there are profound new questions for the physics of strongly interacting systems: the nature of the nucleon, the physics of quark confinement, fundamental symmetries governing hadron decay and the effect of quarks and gluons on nuclear behaviour. Of the new large facilities now planned to respond to these questions the kaon factory is central. It uses very intense (∼100 μA) primary proton beams (∼30 GeV) to generate intense secondary beams of various hadrons and leptons. (author)

  4. APIPIS: the Atomic Physics Ion-Photon Interaction System

    International Nuclear Information System (INIS)

    Johnson, B.M.; Jones, K.W.; Meron, M.; Kostroun, V.O.

    1985-01-01

    A proposed new facility for the study of highly charged heavy ions is described. The basic elements of APIPIS, the Atomic Physics Ion-Photon Interaction System, are: (1) a source of multiply-charged ions; (2) a linear accelerator; (3) a synchrotron storage ring; and (4) a source of high brightness x rays. The placement of a heavy ion storage ring at the x-ray ring of the National Synchrotron Light Source will provide unique opportunities for the study of photo-excitation of heavy ions

  5. Wave chaos in quantum systems with point interaction

    International Nuclear Information System (INIS)

    Albeverio, S.; Seba, P.

    1991-01-01

    The authors study perturbations H of the quantized version H 0 of integrable Hamiltonian systems by point interactions. They relate the eigenvalues of H to the zeros of a certain meromorphic function ξ. Assuming the eigenvalues of H 0 are Poisson distributed, they get detailed information on the joint distribution of the zeros of ξ and give bounds on the probability density for the spacings of eigenvalues of H. Their results confirm the wave chaos phenomenon, as different from the quantum chaos phenomenon predicted by random matrix theory

  6. On the ``Matrix Approach'' to Interacting Particle Systems

    Science.gov (United States)

    de Sanctis, L.; Isopi, M.

    2004-04-01

    Derrida et al. and Schütz and Stinchcombe gave algebraic formulas for the correlation functions of the partially asymmetric simple exclusion process. Here we give a fairly general recipe of how to get these formulas and extend them to the whole time evolution (starting from the generator of the process), for a certain class of interacting systems. We then analyze the algebraic relations obtained to show that the matrix approach does not work with some models such as the voter and the contact processes.

  7. Interactive video audio system: communication server for INDECT portal

    Science.gov (United States)

    Mikulec, Martin; Voznak, Miroslav; Safarik, Jakub; Partila, Pavol; Rozhon, Jan; Mehic, Miralem

    2014-05-01

    The paper deals with presentation of the IVAS system within the 7FP EU INDECT project. The INDECT project aims at developing the tools for enhancing the security of citizens and protecting the confidentiality of recorded and stored information. It is a part of the Seventh Framework Programme of European Union. We participate in INDECT portal and the Interactive Video Audio System (IVAS). This IVAS system provides a communication gateway between police officers working in dispatching centre and police officers in terrain. The officers in dispatching centre have capabilities to obtain information about all online police officers in terrain, they can command officers in terrain via text messages, voice or video calls and they are able to manage multimedia files from CCTV cameras or other sources, which can be interesting for officers in terrain. The police officers in terrain are equipped by smartphones or tablets. Besides common communication, they can reach pictures or videos sent by commander in office and they can respond to the command via text or multimedia messages taken by their devices. Our IVAS system is unique because we are developing it according to the special requirements from the Police of the Czech Republic. The IVAS communication system is designed to use modern Voice over Internet Protocol (VoIP) services. The whole solution is based on open source software including linux and android operating systems. The technical details of our solution are presented in the paper.

  8. Caught in the act: discovering secreted proteins from fungi and oomycetes in action

    DEFF Research Database (Denmark)

    Roth, Doris; Grell, Morten Nedergaard; Jensen, Annette Bruun

    Host-microbe relationships largely rely on secreted proteins like enzymes, virulence factors and antimicrobial peptides. To discover proteins secreted by microbe and host during the interaction with each other, we produced dual-organism cDNA libraries from three different fungus- or oomycete-infe......, by applying a similar strategy with a fungus-only library. As a result, we will show that our approach is widely applicable and allows us to deepen the understanding a variety of different host-microbe systems.......Host-microbe relationships largely rely on secreted proteins like enzymes, virulence factors and antimicrobial peptides. To discover proteins secreted by microbe and host during the interaction with each other, we produced dual-organism cDNA libraries from three different fungus- or oomycete...

  9. Interactive full channel teletext system for cable television nets

    Science.gov (United States)

    Vandenboom, H. P. A.

    1984-08-01

    A demonstration set-up of an interactive full channel teletext (FCT) system for cable TV networks with two-way data communication possibilities was designed and realized. In FCT all image lines are used for teletext data lines. The FCT decoder was placed in the mini-star, and the FCT encoder which provides the FCT signal was placed in the local center. From the FCT signal a number of data lines are selected using an extra FCT decoder. They are placed on the image lines reserved for teletext so that a normal TV receiver equipped with a teletext decoder, can process the selected data lines. For texts not on hand in the FCT signal, a command can be sent to the local center via the data communication path. A cheap and simple system is offered in which the number of commanded pages or books is in principle unlimited, while the used waiting time and channel capacity is limited.

  10. Wind Turbine Converter Control Interaction with Complex Wind Farm Systems

    DEFF Research Database (Denmark)

    Kocewiak, Lukasz Hubert; Hjerrild, Jesper; Bak, Claus Leth

    2013-01-01

    . The same wind turbine converter control strategy is evaluated in two different wind farms. It is emphasised that the grid-side converter controller should be characterised by sufficient harmonic/noise rejection and adjusted depending on wind farms to which it is connected. Various stability indices......This study presents wind turbine converter stability analysis of wind farms in frequency domain. The interaction between the wind turbine control system and the wind farm structure in wind farms is deeply investigated. Two wind farms (i.e. Horns Rev II and Karnice) are taken into consideration...... in this study. It is shown that wind farm components, such as long high-voltage alternating current cables and park transformers, can introduce significant low-frequency series resonances seen from the wind turbine terminals that can affect wind turbine control system operation and overall wind farm stability...

  11. Interacting systems far from equilibrium quantum kinetic theory

    CERN Document Server

    Morawetz, Klaus

    2018-01-01

    This book presents an up-to-date formalism of non-equilibrium Green's functions covering different applications ranging from solid state physics, plasma physics, cold atoms in optical lattices up to relativistic transport and heavy ion collisions. Within the Green's function formalism, the basic sets of equations for these diverse systems are similar, and approximations developed in one field can be adapted to another field. The central object is the self-energy which includes all non-trivial aspects of the system dynamics. The focus is therefore on microscopic processes starting from elementary principles for classical gases and the complementary picture of a single quantum particle in a random potential. This provides an intuitive picture of the interaction of a particle with the medium formed by other particles, on which the Green's function is built on.

  12. AN INTERACTIVE LOGISTICS CENTRE INFORMATION INTEGRATION SYSTEM USING VIRTUAL REALITY

    Directory of Open Access Journals (Sweden)

    S. Hong

    2018-04-01

    Full Text Available The logistics industry plays a very important role in the operation of modern cities. Meanwhile, the development of logistics industry has derived various problems that are urgent to be solved, such as the safety of logistics products. This paper combines the study of logistics industry traceability and logistics centre environment safety supervision with virtual reality technology, creates an interactive logistics centre information integration system. The proposed system utilizes the immerse characteristic of virtual reality, to simulate the real logistics centre scene distinctly, which can make operation staff conduct safety supervision training at any time without regional restrictions. On the one hand, a large number of sensor data can be used to simulate a variety of disaster emergency situations. On the other hand, collecting personnel operation data, to analyse the improper operation, which can improve the training efficiency greatly.

  13. An Interactive Logistics Centre Information Integration System Using Virtual Reality

    Science.gov (United States)

    Hong, S.; Mao, B.

    2018-04-01

    The logistics industry plays a very important role in the operation of modern cities. Meanwhile, the development of logistics industry has derived various problems that are urgent to be solved, such as the safety of logistics products. This paper combines the study of logistics industry traceability and logistics centre environment safety supervision with virtual reality technology, creates an interactive logistics centre information integration system. The proposed system utilizes the immerse characteristic of virtual reality, to simulate the real logistics centre scene distinctly, which can make operation staff conduct safety supervision training at any time without regional restrictions. On the one hand, a large number of sensor data can be used to simulate a variety of disaster emergency situations. On the other hand, collecting personnel operation data, to analyse the improper operation, which can improve the training efficiency greatly.

  14. A Dynamic and Interactive Monitoring System of Data Center Resources

    Directory of Open Access Journals (Sweden)

    Yu Ling-Fei

    2016-01-01

    Full Text Available To maximize the utilization and effectiveness of resources, it is very necessary to have a well suited management system for modern data centers. Traditional approaches to resource provisioning and service requests have proven to be ill suited for virtualization and cloud computing. The manual handoffs between technology teams were also highly inefficient and poorly documented. In this paper, a dynamic and interactive monitoring system for data center resources, ResourceView, is presented. By consolidating all data center management functionality into a single interface, ResourceView shares a common view of the timeline metric status, while providing comprehensive, centralized monitoring of data center physical and virtual IT assets including power, cooling, physical space and VMs, so that to improve availability and efficiency. In addition, servers and VMs can be monitored from several viewpoints such as clusters, racks and projects, which is very convenient for users.

  15. A semiautomated computer-interactive dynamic impact testing system

    International Nuclear Information System (INIS)

    Alexander, D.J.; Nanstad, R.K.; Corwin, W.R.; Hutton, J.T.

    1989-01-01

    A computer-assisted semiautomated system has been developed for testing a variety of specimen types under dynamic impact conditions. The primary use of this system is for the testing of Charpy specimens. Full-, half-, and third-size specimens have been tested, both in the lab and remotely in a hot cell for irradiated specimens. Specimens are loaded into a transfer device which moves the specimen into a chamber, where a hot air gun is used to heat the specimen, or cold nitrogen gas is used for cooling, as required. The specimen is then quickly transferred from the furnace to the anvils and then broken. This system incorporates an instrumented tup to determine the change in voltage during the fracture process. These data are analyzed by the computer system after the test is complete. The voltage-time trace is recorded with a digital oscilloscope, transferred to the computer, and analyzed. The analysis program incorporates several unique features. It interacts with the operator and identifies the maximum voltage during the test, the amount of rapid fracture during the test (if any), and the end of the fracture process. The program then calculates the area to maximum voltage and the total area under the voltage-time curve. The data acquisition and analysis part of the system can also be used to conduct other dynamic testing. Dynamic tear and precracked specimens can be tested with an instrumented tup and analyzed in a similar manner. 3 refs., 7 figs

  16. Network characteristics emerging from agent interactions in balanced distributed system.

    Science.gov (United States)

    Salman, Mahdi Abed; Bertelle, Cyrille; Sanlaville, Eric

    2015-01-01

    A distributed computing system behaves like a complex network, the interactions between nodes being essential information exchanges and migrations of jobs or services to execute. These actions are performed by software agents, which behave like the members of social networks, cooperating and competing to obtain knowledge and services. The load balancing consists in distributing the load evenly between system nodes. It aims at enhancing the resource usage. A load balancing strategy specifies scenarios for the cooperation. Its efficiency depends on quantity, accuracy, and distribution of available information. Nevertheless, the distribution of information on the nodes, together with the initial network structure, may create different logical network structures. In this paper, different load balancing strategies are tested on different network structures using a simulation. The four tested strategies are able to distribute evenly the load so that the system reaches a steady state (the mean response time of the jobs is constant), but it is shown that a given strategy indeed behaves differently according to structural parameters and information spreading. Such a study, devoted to distributed computing systems (DCSs), can be useful to understand and drive the behavior of other complex systems.

  17. Virtual respiratory system for interactive e-learning of spirometry

    Directory of Open Access Journals (Sweden)

    W. Tomalak

    2008-04-01

    Full Text Available Progress in computer simulation technology offers new possibilities for modern medicine. On one hand – virtual organs can help to create animal or human models for research, on the other hand – e-learning or distant learning through Internet is now possible. The aim of our work was to create a system for interactive learning of spirometry (SILS, enabling students or physicians to observe spirometric measurements (flow-volume modified by setting level and kind of abnormalities within the respiratory system. SILS is based on a virtual respiratory system presented previously in several papers. Its main features are: separation of the lungs and chest; anatomical division of the lungs; division of airway resistance into transmural pressure dependent (Rp and lung volume dependent (Rv parts. The one mathematical formula that represents Rp describes both flow limitation (forced expiration and dependence of Raw on lungs volume (small airflows. The output of system are spirometric parameters (as FEV1, FVC, FEV1%FVC and a flow–volume loop constructed according to results of simulation of forced expiration for the chosen abnormality kind and level. As a result – this system may be used in teaching process in medical schools and postgraduate education. We offer access to a basic version of SILS for students and physicians at: www.spirometry.ibib.waw.pl and www.zpigichp.edu.pl. As we expect feedback from users, it is possible to modify user interface or model features to comply with users' requests.

  18. Augmented Robotics Dialog System for Enhancing Human–Robot Interaction

    Science.gov (United States)

    Alonso-Martín, Fernando; Castro-González, Aívaro; de Gorostiza Luengo, Francisco Javier Fernandez; Salichs, Miguel Ángel

    2015-01-01

    Augmented reality, augmented television and second screen are cutting edge technologies that provide end users extra and enhanced information related to certain events in real time. This enriched information helps users better understand such events, at the same time providing a more satisfactory experience. In the present paper, we apply this main idea to human–robot interaction (HRI), to how users and robots interchange information. The ultimate goal of this paper is to improve the quality of HRI, developing a new dialog manager system that incorporates enriched information from the semantic web. This work presents the augmented robotic dialog system (ARDS), which uses natural language understanding mechanisms to provide two features: (i) a non-grammar multimodal input (verbal and/or written) text; and (ii) a contextualization of the information conveyed in the interaction. This contextualization is achieved by information enrichment techniques that link the extracted information from the dialog with extra information about the world available in semantic knowledge bases. This enriched or contextualized information (information enrichment, semantic enhancement or contextualized information are used interchangeably in the rest of this paper) offers many possibilities in terms of HRI. For instance, it can enhance the robot's pro-activeness during a human–robot dialog (the enriched information can be used to propose new topics during the dialog, while ensuring a coherent interaction). Another possibility is to display additional multimedia content related to the enriched information on a visual device. This paper describes the ARDS and shows a proof of concept of its applications. PMID:26151202

  19. An Advanced N -body Model for Interacting Multiple Stellar Systems

    Energy Technology Data Exchange (ETDEWEB)

    Brož, Miroslav [Astronomical Institute of the Charles University, Faculty of Mathematics and Physics, V Holešovičkách 2, CZ-18000 Praha 8 (Czech Republic)

    2017-06-01

    We construct an advanced model for interacting multiple stellar systems in which we compute all trajectories with a numerical N -body integrator, namely the Bulirsch–Stoer from the SWIFT package. We can then derive various observables: astrometric positions, radial velocities, minima timings (TTVs), eclipse durations, interferometric visibilities, closure phases, synthetic spectra, spectral energy distribution, and even complete light curves. We use a modified version of the Wilson–Devinney code for the latter, in which the instantaneous true phase and inclination of the eclipsing binary are governed by the N -body integration. If all of these types of observations are at one’s disposal, a joint χ {sup 2} metric and an optimization algorithm (a simplex or simulated annealing) allow one to search for a global minimum and construct very robust models of stellar systems. At the same time, our N -body model is free from artifacts that may arise if mutual gravitational interactions among all components are not self-consistently accounted for. Finally, we present a number of examples showing dynamical effects that can be studied with our code and we discuss how systematic errors may affect the results (and how to prevent this from happening).

  20. Anvil Forecast Tool in the Advanced Weather Interactive Processing System

    Science.gov (United States)

    Barrett, Joe H., III; Hood, Doris

    2009-01-01

    Meteorologists from the 45th Weather Squadron (45 WS) and National Weather Service Spaceflight Meteorology Group (SMG) have identified anvil forecasting as one of their most challenging tasks when predicting the probability of violations of the Lightning Launch Commit Criteria and Space Shuttle Flight Rules. As a result, the Applied Meteorology Unit (AMU) was tasked to create a graphical overlay tool for the Meteorological Interactive Data Display System (MIDDS) that indicates the threat of thunderstorm anvil clouds, using either observed or model forecast winds as input. The tool creates a graphic depicting the potential location of thunderstorm anvils one, two, and three hours into the future. The locations are based on the average of the upper level observed or forecasted winds. The graphic includes 10 and 20 n mi standoff circles centered at the location of interest, as well as one-, two-, and three-hour arcs in the upwind direction. The arcs extend outward across a 30 sector width based on a previous AMU study that determined thunderstorm anvils move in a direction plus or minus 15 of the upper-level wind direction. The AMU was then tasked to transition the tool to the Advanced Weather Interactive Processing System (AWIPS). SMG later requested the tool be updated to provide more flexibility and quicker access to model data. This presentation describes the work performed by the AMU to transition the tool into AWIPS, as well as the subsequent improvements made to the tool.

  1. A Crowdsensing-Based Real-Time System for Finger Interactions in Intelligent Transport System

    Directory of Open Access Journals (Sweden)

    Chengqun Song

    2017-01-01

    Full Text Available Crowdsensing leverages human intelligence/experience from the general public and social interactions to create participatory sensor networks, where context-aware and semantically complex information is gathered, processed, and shared to collaboratively solve specific problems. This paper proposes a real-time projector-camera finger system based on the crowdsensing, in which user can interact with a computer by bare hand touching on arbitrary surfaces. The interaction process of the system can be completely carried out automatically, and it can be used as an intelligent device in intelligent transport system where the driver can watch and interact with the display information while driving, without causing visual distractions. A single camera is used in the system to recover 3D information of fingertip for hand touch detection. A linear-scanning method is used in the system to determine the touch for increasing the users’ collaboration and operationality. Experiments are performed to show the feasibility of the proposed system. The system is robust to different lighting conditions. The average percentage of correct hand touch detection of the system is 92.0% and the average time of processing one video frame is 30 milliseconds.

  2. Interaction systems design and the protocol- and middleware-centred paradigms in distributed application development

    OpenAIRE

    Andrade Almeida, João; van Sinderen, Marten J.; Quartel, Dick; Ferreira Pires, Luis

    2003-01-01

    This paper aims at demonstrating the benefits and importance of interaction systems design in the development of distributed applications. We position interaction systems design with respect to two paradigms that have influenced the design of distributed applications: the middleware-centred and the protocol-centred paradigm. We argue that interaction systems that support application-level interactions should be explicitly designed, using the externally observable behaviour of the interaction ...

  3. Bispectral pairwise interacting source analysis for identifying systems of cross-frequency interacting brain sources from electroencephalographic or magnetoencephalographic signals

    Science.gov (United States)

    Chella, Federico; Pizzella, Vittorio; Zappasodi, Filippo; Nolte, Guido; Marzetti, Laura

    2016-05-01

    Brain cognitive functions arise through the coordinated activity of several brain regions, which actually form complex dynamical systems operating at multiple frequencies. These systems often consist of interacting subsystems, whose characterization is of importance for a complete understanding of the brain interaction processes. To address this issue, we present a technique, namely the bispectral pairwise interacting source analysis (biPISA), for analyzing systems of cross-frequency interacting brain sources when multichannel electroencephalographic (EEG) or magnetoencephalographic (MEG) data are available. Specifically, the biPISA makes it possible to identify one or many subsystems of cross-frequency interacting sources by decomposing the antisymmetric components of the cross-bispectra between EEG or MEG signals, based on the assumption that interactions are pairwise. Thanks to the properties of the antisymmetric components of the cross-bispectra, biPISA is also robust to spurious interactions arising from mixing artifacts, i.e., volume conduction or field spread, which always affect EEG or MEG functional connectivity estimates. This method is an extension of the pairwise interacting source analysis (PISA), which was originally introduced for investigating interactions at the same frequency, to the study of cross-frequency interactions. The effectiveness of this approach is demonstrated in simulations for up to three interacting source pairs and for real MEG recordings of spontaneous brain activity. Simulations show that the performances of biPISA in estimating the phase difference between the interacting sources are affected by the increasing level of noise rather than by the number of the interacting subsystems. The analysis of real MEG data reveals an interaction between two pairs of sources of central mu and beta rhythms, localizing in the proximity of the left and right central sulci.

  4. Artificial ferroic systems: novel functionality from structure, interactions and dynamics

    International Nuclear Information System (INIS)

    Heyderman, L J; Stamps, R L

    2013-01-01

    Lithographic processing and film growth technologies are continuing to advance, so that it is now possible to create patterned ferroic materials consisting of arrays of sub-1 μm elements with high definition. Some of the most fascinating behaviour of these arrays can be realised by exploiting interactions between the individual elements to create new functionality. The properties of these artificial ferroic systems differ strikingly from those of their constituent components, with novel emergent behaviour arising from the collective dynamics of the interacting elements, which are arranged in specific designs and can be activated by applying magnetic or electric fields. We first focus on artificial spin systems consisting of arrays of dipolar-coupled nanomagnets and, in particular, review the field of artificial spin ice, which demonstrates a wide range of fascinating phenomena arising from the frustration inherent in particular arrangements of nanomagnets, including emergent magnetic monopoles, domains of ordered macrospins, and novel avalanche behaviour. We outline how demagnetisation protocols have been employed as an effective thermal anneal in an attempt to reach the ground state, comment on phenomena that arise in thermally activated systems and discuss strategies for selectively generating specific configurations using applied magnetic fields. We then move on from slow field and temperature driven dynamics to high frequency phenomena, discussing spinwave excitations in the context of magnonic crystals constructed from arrays of patterned magnetic elements. At high frequencies, these arrays are studied in terms of potential applications including magnetic logic, linear and non-linear microwave optics, and fast, efficient switching, and we consider the possibility to create tunable magnonic crystals with artificial spin ice. Finally, we discuss how functional ferroic composites can be incorporated to realise magnetoelectric effects. Specifically, we discuss

  5. Artificial ferroic systems: novel functionality from structure, interactions and dynamics.

    Science.gov (United States)

    Heyderman, L J; Stamps, R L

    2013-09-11

    Lithographic processing and film growth technologies are continuing to advance, so that it is now possible to create patterned ferroic materials consisting of arrays of sub-1 μm elements with high definition. Some of the most fascinating behaviour of these arrays can be realised by exploiting interactions between the individual elements to create new functionality. The properties of these artificial ferroic systems differ strikingly from those of their constituent components, with novel emergent behaviour arising from the collective dynamics of the interacting elements, which are arranged in specific designs and can be activated by applying magnetic or electric fields. We first focus on artificial spin systems consisting of arrays of dipolar-coupled nanomagnets and, in particular, review the field of artificial spin ice, which demonstrates a wide range of fascinating phenomena arising from the frustration inherent in particular arrangements of nanomagnets, including emergent magnetic monopoles, domains of ordered macrospins, and novel avalanche behaviour. We outline how demagnetisation protocols have been employed as an effective thermal anneal in an attempt to reach the ground state, comment on phenomena that arise in thermally activated systems and discuss strategies for selectively generating specific configurations using applied magnetic fields. We then move on from slow field and temperature driven dynamics to high frequency phenomena, discussing spinwave excitations in the context of magnonic crystals constructed from arrays of patterned magnetic elements. At high frequencies, these arrays are studied in terms of potential applications including magnetic logic, linear and non-linear microwave optics, and fast, efficient switching, and we consider the possibility to create tunable magnonic crystals with artificial spin ice. Finally, we discuss how functional ferroic composites can be incorporated to realise magnetoelectric effects. Specifically, we discuss

  6. Mirror Neuron System and Mentalizing System connect during online social interaction.

    Science.gov (United States)

    Sperduti, Marco; Guionnet, Sophie; Fossati, Philippe; Nadel, Jacqueline

    2014-08-01

    Two sets of brain areas are repeatedly reported in neuroimaging studies on social cognition: the Mirror Neuron System and the Mentalizing System. The Mirror System is involved in goal understanding and has been associated with several emotional and cognitive functions central to social interaction, ranging from empathy to gestural communication and imitation. The Mentalizing System is recruited in tasks requiring cognitive processes such as self-reference and understanding of other's intentions. Although theoretical accounts for an interaction between the two systems have been proposed, little is known about their synergy during social exchanges. In order to explore this question, we have recorded brain activity by means of functional MRI during live social exchanges based on reciprocal imitation of hand gestures. Here, we investigate, using the method of psychophysiological interaction, the changes in functional connectivity of the Mirror System due to the conditions of interest (being imitated, imitating) compared with passive observation of hand gestures. We report a strong coupling between the Mirror System and the Mentalizing System during the imitative exchanges. Our findings suggest a complementary role of the two networks during social encounters. The Mirror System would engage in the preparation of own actions and the simulation of other's actions, while the Mentalizing System would engage in the anticipation of the other's intention and thus would participate to the co-regulation of reciprocal actions. Beyond a specific effect of imitation, the design used offers the opportunity to tackle the role of role-switching in an interpersonal account of social cognition.

  7. Sorbic acid interaction with sulfur dioxide in model food systems

    Energy Technology Data Exchange (ETDEWEB)

    Namor, O G

    1987-01-01

    The first chapter deals with the chemistry of sorbic acid and sulfur dioxide. The second chapter describes a study of the degradation products of sorbic acid, in aqueous systems, in the presence of sulfur dioxide and a possible mechanism for the occurrence of these products is proposed. Chapter three deals with the preparation and degradation of 6-(/sup 13/C)sorbic acid in order to find evidence for, or against, the mechanism proposed in chapter two. It also gives details of syntheses attempted in order to obtain 6- (/sup 13/C)sorbic acid. The interaction of sorbic acid and sulfur dioxide in real food systems is the subject of the fourth chapter. The food systems studied were mayonnaise, tomato puree, orange juice and cottage cheese. The effect of packaging on the rate of degradation of sorbic acid was also investigated. The final chapter deals with a microbiological study of two homologues of sorbic acid, 2,4-heptadienoic acid, 2,4-octadienoic acid. The fungicidal activity of these two compounds, towards selected fungi, was analyzed. 4-Oxobut-2-enoic acid, a degradation product of sorbic acid in aqueous systems, was also analyzed as a possible fungistat.

  8. Huggy Pajama: A Remote Interactive Touch and Hugging System

    Science.gov (United States)

    Cheok, Adrian David

    Huggy Pajama is a novel wearable system aimed at promoting physical interaction in remote communication between parent and child. This system enables parents and children to hug one another through a hugging interface device and a wearable, hug reproducing pajama connected through the Internet. The hug input device is a small, mobile doll with an embedded pressure sensing circuit that is able to accurately sense varying levels of pressure along the range of human touch produced from natural touch. This device sends hug signals to a haptic jacket that simulates the feeling of being hugged to the wearer. It features air pocket actuators that reproduce hug sensations, heating elements to produce warmth that accompanies hugs, and a color changing pattern and accessory to indicate distance of separation and communicate expressions. In this chapter, we present the system design of Huggy Pajama. We also show results from quantitative and qualitative user studies which show the effectiveness of the system simulating an actual human touch. Results also indicate an increased sense of presence between parents and children when used as an added component to instant messaging and video chat communication.

  9. Modelling an Interactive Road Signs System, Using Petri Nets

    Directory of Open Access Journals (Sweden)

    Kombe Timothee

    2017-03-01

    Full Text Available This paper is a contribution to the problems of road insecurity in Africa. Due to non-respect of road sign and to the lack of signing, roads have become places of all dangers. It becomes imperative to establish an interaction between the authorities and the offending drivers. To reach this goal, we modelled an interactive road-vehicle-signage system, who locally informs the driver on the requirements of traffic signs. This model having interest only in the event of driving by bad weather or deterioration of panels, we are amending by inserting functions aimed to warn and punish the driver in the event of maintenance of an offense. Indeed, when the driver is about to commit a fault, firstly the system issues a warming (visual, audible or mechanical. Then, a message (SMS is sent to the authorities. We include the concept of floating process engaged by devices other than the signage. We show that, with a few considerations, from the functional point of view, they are identical to the process engaged by the signage. Furthermore, in terms of performance, the model renewed warnings that occurred just before the end panel of prohibitions. It stores messages of offenses occurred without the network, then notifies them when a network is detected. We propose algorithms for incremental design and analysis of the model, whose processes are activated and / or are extinguished, according to the type of sign or tag encountered. We show by simulation and by linear algebra that, the model retains its properties of absence of blocking and boundedness during the evolution of the system, hence its validation.

  10. Phase equilibria and molecular interaction studies on (naphthols + vanillin) systems

    International Nuclear Information System (INIS)

    Gupta, Preeti; Agrawal, Tanvi; Das, Shiva Saran; Singh, Nakshatra Bahadur

    2012-01-01

    Highlights: ► Phase equilibria of (naphthol + vanillin) systems have been studied for the first time. ► Eutectic type phase diagrams are obtained. ► Eutectic mixtures show nonideal behaviour. ► There is a weak molecular interaction between the components in the eutectic mixtures. ► α-Naphthol–vanillin eutectic is more stable as compared to β-naphthol–vanillin. - Abstract: Phase equilibria between (α-naphthol + vanillin) and (β-naphthol + vanillin) systems have been studied by thaw-melt method and the results show the formation of simple eutectic mixtures. Crystallization velocities of components and eutectic mixtures were determined at different stages under cooling. With the help of differential scanning calorimeter (DSC), the enthalpy of fusion of components and eutectic mixtures was determined and from the values excess thermodynamic functions viz., excess Gibbs free energy (G E ), excess entropy (S E ), excess enthalpy (H E ) of hypo-, hyper- and eutectic mixtures were calculated. Flexural strength measurements were made in order to understand the non-ideal nature of eutectics. FT-IR spectral studies indicate the formation of hydrogen bond in the eutectic mixture. Anisotropic and isotropic microstructural studies of components, hypo-, hyper- and eutectic mixtures were made. Jackson’s roughness parameter was calculated and found to be greater than 2 suggesting the faceted morphology with irregular structures. The overall results have shown that there is a weak molecular interaction between the components in the eutectic mixtures and the (α-naphthol + vanillin) eutectic is more stable as compared to the (β-naphthol + vanillin) eutectic system.

  11. The woodrat gut microbiota as an experimental system for understanding microbial metabolism of dietary toxins

    Directory of Open Access Journals (Sweden)

    Kevin D. Kohl

    2016-07-01

    Full Text Available The microbial communities inhabiting the alimentary tracts of mammals, particularly those of herbivores, are estimated to be one of the densest microbial reservoirs on Earth. The significance of these gut microbes in influencing the physiology, ecology and evolution of their hosts is only beginning to be realized. To understand the microbiome of herbivores with a focus on nutritional ecology, while evaluating the roles of host evolution and environment in sculpting microbial diversity, we have developed an experimental system consisting of the microbial communities of several species of herbivorous woodrats (genus Neotoma that naturally feed on a variety of dietary toxins. We designed this system to investigate the long-standing, but experimentally neglected hypothesis that ingestion of toxic diets by herbivores is facilitated by the gut microbiota. Like several other rodent species, the woodrat stomach has a sacculated, nongastric foregut portion. We have documented a dense and diverse community of microbes in the woodrat foregut, with several genera potentially capable of degrading dietary toxins and/or playing a role in stimulating hepatic detoxification enzymes of the host. The biodiversity of these gut microbes appears to be a function of host evolution, ecological experience and diet, such that dietary toxins increase microbial diversity in hosts with experience with these toxins while novel toxins depress microbial diversity. These microbial communities are critical to the ingestion of a toxic diet as reducing the microbial community with antibiotics impairs the host’s ability to feed on dietary toxins. Furthermore, the detoxification capacity of gut microbes can be transferred from Neotoma both intra and interspecifically to naïve animals that lack ecological and evolutionary history with these toxins. In addition to advancing our knowledge of complex host-microbes interactions, this system holds promise for identifying microbes that

  12. Mother, Father, and Infant as an Interactive System.

    Science.gov (United States)

    Pedersen, Frank A.

    This study investigates three types of reciprocal interactions among members of the family unit (father, mother and infant): father-infant interaction affecting child's development, father-infant interaction affecting mother's behavior, and husband-wife interaction affecting mother's behavior. Data from a sample of 39 healthy first-born infants…

  13. How well can DFT reproduce key interactions in Ziegler-Natta systems?

    KAUST Repository

    Correa, Andrea; Bahri-Laleh, Naeimeh; Cavallo, Luigi

    2013-01-01

    The performance of density functional theory in reproducing some of the main interactions occurring in MgCl2-supported Ziegler-Natta catalytic systems is assessed. Eight model systems, representatives of key interactions occurring in Ziegler

  14. Does synchronization reflect a true interaction in the cardiorespiratory system?

    Science.gov (United States)

    Toledo, E; Akselrod, S; Pinhas, I; Aravot, D

    2002-01-01

    Cardiorespiratory synchronization, studied within the framework of phase synchronization, has recently raised interest as one of the interactions in the cardiorespiratory system. In this work, we present a quantitative approach to the analysis of this nonlinear phenomenon. Our primary aim is to determine whether synchronization between HR and respiration rate is a real phenomenon or a random one. First, we developed an algorithm, which detects epochs of synchronization automatically and objectively. The algorithm was applied to recordings of respiration and HR obtained from 13 normal subjects and 13 heart transplant patients. Surrogate data sets were constructed from the original recordings, specifically lacking the coupling between HR and respiration. The statistical properties of synchronization in the two data sets and in their surrogates were compared. Synchronization was observed in all groups: in normal subjects, in the heart transplant patients and in the surrogates. Interestingly, synchronization was less abundant in normal subjects than in the transplant patients, indicating that the unique physiological condition of the latter promote cardiorespiratory synchronization. The duration of synchronization epochs was significantly shorter in the surrogate data of both data sets, suggesting that at least some of the synchronization epochs are real. In view of those results, cardiorespiratory synchronization, although not a major feature of cardiorespiratory interaction, seems to be a real phenomenon rather than an artifact.

  15. Grammar Is a System That Characterizes Talk in Interaction.

    Science.gov (United States)

    Ginzburg, Jonathan; Poesio, Massimo

    2016-01-01

    Much of contemporary mainstream formal grammar theory is unable to provide analyses for language as it occurs in actual spoken interaction. Its analyses are developed for a cleaned up version of language which omits the disfluencies, non-sentential utterances, gestures, and many other phenomena that are ubiquitous in spoken language. Using evidence from linguistics, conversation analysis, multimodal communication, psychology, language acquisition, and neuroscience, we show these aspects of language use are rule governed in much the same way as phenomena captured by conventional grammars. Furthermore, we argue that over the past few years some of the tools required to provide a precise characterizations of such phenomena have begun to emerge in theoretical and computational linguistics; hence, there is no reason for treating them as "second class citizens" other than pre-theoretical assumptions about what should fall under the purview of grammar. Finally, we suggest that grammar formalisms covering such phenomena would provide a better foundation not just for linguistic analysis of face-to-face interaction, but also for sister disciplines, such as research on spoken dialogue systems and/or psychological work on language acquisition.

  16. Intelligent interactive multimedia systems and services in practice

    CERN Document Server

    Virvou, Maria; Jain, Lakhmi; Howlett, Robert; Watanabe, Toyohide

    2015-01-01

    This research book presents some specific multimedia systems that have been developed and applied in practice. More specifically, it consists of an editorial, an introductory chapter and six chapters as below.   ·         Use of Multi-attribute Decision Making for Combining Audio-Lingual and Visual-Facial Modalities in Emotion Recognition. ·         Cooperative Learning assisted by Automatic Classification within Social Networking Services. ·         Improving Peer-to-Peer Communication in e-Learning by Development of an Advanced Messaging System. ·         Fuzzy-based Digital Video Stabilization in Static Scenes. ·         Development of Architecture, Information Archive and Multimedia Formats for Digital e-Libraries. ·         Layered Ontological Image for Intelligent Interaction to extend User Capabilities on Multimedia Systems in a Folksonomy Driven Environment.  

  17. Current understanding of interactions between nanoparticles and the immune system

    International Nuclear Information System (INIS)

    Dobrovolskaia, Marina A.; Shurin, Michael; Shvedova, Anna A.

    2016-01-01

    The delivery of drugs, antigens, and imaging agents benefits from using nanotechnology-based carriers. The successful translation of nanoformulations to the clinic involves thorough assessment of their safety profiles, which, among other end-points, includes evaluation of immunotoxicity. The past decade of research focusing on nanoparticle interaction with the immune system has been fruitful in terms of understanding the basics of nanoparticle immunocompatibility, developing a bioanalytical infrastructure to screen for nanoparticle-mediated immune reactions, beginning to uncover the mechanisms of nanoparticle immunotoxicity, and utilizing current knowledge about the structure–activity relationship between nanoparticles' physicochemical properties and their effects on the immune system to guide safe drug delivery. In the present review, we focus on the most prominent pieces of the nanoparticle–immune system puzzle and discuss the achievements, disappointments, and lessons learned over the past 15 years of research on the immunotoxicity of engineered nanomaterials. - Graphical abstract: API — active pharmaceutical ingredient; NP — nanoparticles; PCP — physicochemical properties, CARPA — complement activation-related pseudoallergy, ICH — International Conference on Harmonization. Display Omitted - Highlights: • Achievements, disappointments and lessons learned over past decade are reviewed. • Areas in focus include characterization, immunotoxicity and utility in drug delivery. • Future direction focusing on mechanistic immunotoxicity studies is proposed.

  18. Progress in EEG-Based Brain Robot Interaction Systems

    Directory of Open Access Journals (Sweden)

    Xiaoqian Mao

    2017-01-01

    Full Text Available The most popular noninvasive Brain Robot Interaction (BRI technology uses the electroencephalogram- (EEG- based Brain Computer Interface (BCI, to serve as an additional communication channel, for robot control via brainwaves. This technology is promising for elderly or disabled patient assistance with daily life. The key issue of a BRI system is to identify human mental activities, by decoding brainwaves, acquired with an EEG device. Compared with other BCI applications, such as word speller, the development of these applications may be more challenging since control of robot systems via brainwaves must consider surrounding environment feedback in real-time, robot mechanical kinematics, and dynamics, as well as robot control architecture and behavior. This article reviews the major techniques needed for developing BRI systems. In this review article, we first briefly introduce the background and development of mind-controlled robot technologies. Second, we discuss the EEG-based brain signal models with respect to generating principles, evoking mechanisms, and experimental paradigms. Subsequently, we review in detail commonly used methods for decoding brain signals, namely, preprocessing, feature extraction, and feature classification, and summarize several typical application examples. Next, we describe a few BRI applications, including wheelchairs, manipulators, drones, and humanoid robots with respect to synchronous and asynchronous BCI-based techniques. Finally, we address some existing problems and challenges with future BRI techniques.

  19. Star-planet interactions and dynamical evolution of exoplanetary systems

    Directory of Open Access Journals (Sweden)

    Damiani Cilia

    2015-01-01

    Full Text Available The dynamical evolution of planetary systems, after the evaporation of the accretion disk, is the result of the competition between tidal dissipation and the net angular momentum loss of the system. The description of the diversity of orbital configurations, and correlations between parameters of the observed system (e.g. in the case of hot jupiters, is still limited by our understanding of the transport of angular momentum within the stars, and its effective loss by magnetic braking. After discussing the challenges of modelling tidal evolution for exoplanets, I will review recent results showing the importance of tidal interactions to test models of planetary formation. This kind of studies rely on the determination of stellar radii, masses and ages. Major advances will thus be obtained with the results of the PLATO 2.0 mission, selected as the next M-class mission of ESA’s Cosmic Vision plan, that will allow the complete characterisation of host stars using asteroseismology.

  20. Interactive orbital proximity operations planning system instruction and training guide

    Science.gov (United States)

    Grunwald, Arthur J.; Ellis, Stephen R.

    1994-01-01

    This guide instructs users in the operation of a Proximity Operations Planning System. This system uses an interactive graphical method for planning fuel-efficient rendezvous trajectories in the multi-spacecraft environment of the space station and allows the operator to compose a multi-burn transfer trajectory between orbit initial chaser and target trajectories. The available task time (window) of the mission is predetermined and the maneuver is subject to various operational constraints, such as departure, arrival, spatial, plume impingement, and en route passage constraints. The maneuvers are described in terms of the relative motion experienced in a space station centered coordinate system. Both in-orbital plane as well as out-of-orbital plane maneuvering is considered. A number of visual optimization aids are used for assisting the operator in reaching fuel-efficient solutions. These optimization aids are based on the Primer Vector theory. The visual feedback of trajectory shapes, operational constraints, and optimization functions, provided by user-transparent and continuously active background computations, allows the operator to make fast, iterative design changes that rapidly converge to fuel-efficient solutions. The planning tool is an example of operator-assisted optimization of nonlinear cost functions.

  1. Interactive Computer-Enhanced Remote Viewing System (ICERVS)

    International Nuclear Information System (INIS)

    1993-08-01

    The Integrated Computer-Enhanced Remote Viewing System (ICERVS) supports the robotic remediation of hazardous environments such as underground storage tanks, buried waste sites, and contaminated production facilities. The success of these remediation missions will depend on reliable geometric descriptions of the work environment in order to achieve effective task planning, path planning, and collision avoidance. ICERVS provides a means for deriving a reliable geometric description more effectively and efficiently than current systems by combining a number of technologies: Sensing of the environment to acquire dimensional and material property data; integration of acquired data into a common data structure (based on octree technology); presentation of data to robotic task planners for analysis and visualization; interactive synthesis of geometric/surface models to denote features of interest in the environment and transfer of this information to robot control and collision avoidance systems. A key feature of ICERVS is that it will enable an operator to match xyz data from a sensor with surface models of the same region in space. This capability will help operators to better manage the complexities of task and path planning in three-dimensional (3D) space, thereby leading to safer and more effective remediation. The Phase 1 work performed by MTI has brought the ICERVS design to Maturity Level 3, Subscale Major Subsystem, and met the established success criteria

  2. Current understanding of interactions between nanoparticles and the immune system

    Energy Technology Data Exchange (ETDEWEB)

    Dobrovolskaia, Marina A., E-mail: marina@mail.nih.gov [Nanotechnology Characterization Laboratory, Cancer Research Technology Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, NCI at Frederick, Frederick, MD 21702 (United States); Shurin, Michael [Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213 (United States); Department of Immunology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213 (United States); Shvedova, Anna A., E-mail: ats1@cdc.gov [Health Effects Laboratory Division, National Institute of Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV 26505 (United States); Department of Physiology and Pharmacology, West Virginia University, Morgantown, WV 26506 (United States)

    2016-05-15

    The delivery of drugs, antigens, and imaging agents benefits from using nanotechnology-based carriers. The successful translation of nanoformulations to the clinic involves thorough assessment of their safety profiles, which, among other end-points, includes evaluation of immunotoxicity. The past decade of research focusing on nanoparticle interaction with the immune system has been fruitful in terms of understanding the basics of nanoparticle immunocompatibility, developing a bioanalytical infrastructure to screen for nanoparticle-mediated immune reactions, beginning to uncover the mechanisms of nanoparticle immunotoxicity, and utilizing current knowledge about the structure–activity relationship between nanoparticles' physicochemical properties and their effects on the immune system to guide safe drug delivery. In the present review, we focus on the most prominent pieces of the nanoparticle–immune system puzzle and discuss the achievements, disappointments, and lessons learned over the past 15 years of research on the immunotoxicity of engineered nanomaterials. - Graphical abstract: API — active pharmaceutical ingredient; NP — nanoparticles; PCP — physicochemical properties, CARPA — complement activation-related pseudoallergy, ICH — International Conference on Harmonization. Display Omitted - Highlights: • Achievements, disappointments and lessons learned over past decade are reviewed. • Areas in focus include characterization, immunotoxicity and utility in drug delivery. • Future direction focusing on mechanistic immunotoxicity studies is proposed.

  3. Thermal entanglement and teleportation in a dipolar interacting system

    Energy Technology Data Exchange (ETDEWEB)

    Castro, C.S., E-mail: ccastro@if.uff.br [Instituto de Física, Universidade Federal Fluminense, Av. Gal. Milton Tavares de Souza s/n, Gragoatá, 24210-346 Niterói, RJ (Brazil); Centro de Formação de Professores, Universidade Federal do Recôncavo da Bahia, Av. Nestor de Mello Pita, n. 535, 45.300-000 Amargosa, BA (Brazil); Duarte, O.S.; Pires, D.P.; Soares-Pinto, D.O. [Instituto de Física de São Carlos, Universidade de São Paulo, P.O. Box 369, São Carlos, 13560-970 SP (Brazil); Reis, M.S. [Instituto de Física, Universidade Federal Fluminense, Av. Gal. Milton Tavares de Souza s/n, Gragoatá, 24210-346 Niterói, RJ (Brazil)

    2016-04-22

    Quantum teleportation, which depends on entangled states, is a fascinating subject and an important branch of quantum information processing. The present work reports the use of a dipolar spin thermal system as a noisy quantum channel to perform quantum teleportation. Non-locality, tested by violation of Bell's inequality and thermal entanglement, measured by negativity, shows that for the present model all entangled states, even those that do not violate Bell's inequality, are useful for teleportation. - Highlights: • The effects of a dipolar interaction between two spins on their degree of entanglement and non-locality is reported. • The model presents some degree of non-locality and entanglement at a given coupling parameters. • It is shown how the magnetic anisotropies can influence the fidelity of teleportation.

  4. Lagrange formalism for a system of several fluids interacting electromagnetically

    International Nuclear Information System (INIS)

    Vuillemin, M.

    1964-01-01

    After giving the Lagrange expression for a conducting fluid in an external electromagnetic field, the author shows that a Lagrange expression exists for describing the evolution of a system of interacting fluids obtained by adding the Lagrange expression of each fluid.to that of the electromagnetic field. By variation are obtained the fluid movement equation coupled to the Maxwell equations. It is shown that the study of small movements around a stationary state can be deduced from the Lagrange equation expanded to the second power order of the perturbation. It is then possible to deduce the normal mode equations and the study the stability by examining the modes which are marginally stable. (author) [fr

  5. Challenge-driven attention: interacting frontal and brainstem systems

    Directory of Open Access Journals (Sweden)

    Rajeev D S Raizada

    2008-03-01

    Full Text Available The world is an unpredictable place, presenting challenges that fl uctuate from moment to moment. However, the neural systems for responding to such challenges are far from fully understood. Using fMRI, we studied an audiovisual task in which the trials' diffi culty and onset times varied unpredictably. Two regions were found to increase their activation for challenging trials, with their activities strongly correlated: right frontal cortex and the brainstem. The frontal area matched regions found in previous human studies of cognitive control, and activated in a graded manner with increasing task diffi culty. The brainstem responded only to the most diffi cult trials, showing a phasic activity pattern paralleling locus coeruleus recordings in monkeys. These results reveal a bridge between animal and human studies, and suggest interacting roles for the brainstem and right frontal cortex: the brainstem may signal that an attentional challenge is occurring, while right frontal cortex allocates cognitive resources in response.

  6. Nonresonant interaction of ultrashort electromagnetic pulses with multilevel quantum systems

    Science.gov (United States)

    Belenov, E.; Isakov, V.; Nazarkin, A.

    1994-01-01

    Some features of the excitation of multilevel quantum systems under the action of electromagnetic pulses which are shorter than the inverse frequency of interlevel transitions are considered. It is shown that the interaction is characterized by a specific type of selectivity which is not connected with the resonant absorption of radiation. The simplest three-level model displays the inverse population of upper levels. The effect of an ultrashort laser pulse on a multilevel molecule was regarded as an instant reception of the oscillation velocity by the oscillator and this approach showed an effective excitation and dissociation of the molecule. The estimations testify to the fact that these effects can be observed using modern femtosecond lasers.

  7. Common cause failure and systems interactions issues - an overview

    International Nuclear Information System (INIS)

    Worledge, D.H.; Chu, B.B.; Conradi, L.L.; Smith, A.M.

    1985-01-01

    Common cause failures (CCFs) and systems interactions (SIs) are two concerns which have received significant attention over the years. Although many large and varied efforts have been directed toward these concerns, their resolution is less than satisfactory. Problems continue to exist, both in terms of understanding the basic issues represented by these concerns, and the perceived need for protection against their potentially harmful effects. This paper presents the results of recent EPRI work to provide a basis of understanding of these issues. Based on that improved understanding, a more appropriate way of defining and approaching the underlying technical questions is suggested. The current means of addressing the CCF and SI concerns are discussed and areas of additional activity needed to allow a more effective resolution are identified

  8. Two interacting spins in external fields. Four-level systems

    Energy Technology Data Exchange (ETDEWEB)

    Bagrov, V.G.; Baldiotti, M.C.; Gitman, D.M. [Instituto de Fisica, Universidade de Sao Paulo, Caixa Postal 66318-CEP, 05315-970 Sao Paulo, S.P. (Brazil); Levin, A.D. [Dexter Research Center (United States)

    2007-04-15

    In the present article, we consider the so-called two-spin equation that describes four-level quantum systems. Recently, these systems attract attention due to their relation to the problem of quantum computation. We study general properties of the two-spin equation and show that the problem for certain external backgrounds can be identified with the problem of one spin in an appropriate background. This allows one to generate a number of exact solutions for two-spin equations on the basis of already known exact solutions of the one-spin equation. Besides, we present some exact solutions for the two-spin equation with an external background different for each spin but having the same direction. We study the eigenvalue problem for a time-independent spin interaction and a time-independent external background. A possible analogue of the Rabi problem for the two-spin equation is defined. We present its exact solution and demonstrate the existence of magnetic resonances in two specific frequencies, one of them coinciding with the Rabi frequency, and the other depending on the rotating field magnitude. The resonance that corresponds to the second frequency is suppressed with respect to the first one. (Abstract Copyright [2007], Wiley Periodicals, Inc.)

  9. A study of the phi phi system in hadronic interactions

    International Nuclear Information System (INIS)

    Thompson, I.R.M.

    1984-05-01

    The thesis presents a study of the phi phi system in hadronic interactions. Data were collected from the reaction π - Be → phi phiX, at 85 GeV/c, using the CERN OMEGA Spectrometer. The phi phi system was of interest because it has been suggested that the hadronic production of the Jsup(p)=O - hidden charm state etac(2980) may be observed through the decay to two phi mesons, and because it is expected that gluonium states exist in the mass range 2.0 to 2.5 GeV/c 2 , and these should decay to two phi mesons. Experimental details and data analysis of the experiment are given. The phi phi mass resolution was determined from the errors on the track parameters of the particles and from the examination of the observed phi and K 0 signals. The mass resolution was used in an examination of the phi phi mass spectrum for narrow resonances and in the estimation of the upper limits of the cross-section for a narrow resonance. (U.K.)

  10. Exact tensor network ansatz for strongly interacting systems

    Science.gov (United States)

    Zaletel, Michael P.

    It appears that the tensor network ansatz, while not quite complete, is an efficient coordinate system for the tiny subset of a many-body Hilbert space which can be realized as a low energy state of a local Hamiltonian. However, we don't fully understand precisely which phases are captured by the tensor network ansatz, how to compute their physical observables (even numerically), or how to compute a tensor network representation for a ground state given a microscopic Hamiltonian. These questions are algorithmic in nature, but their resolution is intimately related to understanding the nature of quantum entanglement in many-body systems. For this reason it is useful to compute the tensor network representation of various `model' wavefunctions representative of different phases of matter; this allows us to understand how the entanglement properties of each phase are expressed in the tensor network ansatz, and can serve as test cases for algorithm development. Condensed matter physics has many illuminating model wavefunctions, such as Laughlin's celebrated wave function for the fractional quantum Hall effect, the Bardeen-Cooper-Schrieffer wave function for superconductivity, and Anderson's resonating valence bond ansatz for spin liquids. This thesis presents some results on exact tensor network representations of these model wavefunctions. In addition, a tensor network representation is given for the time evolution operator of a long-range one-dimensional Hamiltonian, which allows one to numerically simulate the time evolution of power-law interacting spin chains as well as two-dimensional strips and cylinders.

  11. Interaction of the tick immune system with transmitted pathogens

    Directory of Open Access Journals (Sweden)

    Ondrej eHajdusek

    2013-07-01

    Full Text Available Ticks are hematophagous arachnids transmitting a wide variety of pathogens including viruses, bacteria, and protozoans to their vertebrate hosts. The tick vector competence has to be intimately linked to the ability of transmitted pathogens to evade tick defense mechanisms encountered on their route through the tick body comprising midgut, hemolymph, salivary glands or ovaries. Tick innate immunity is, like in other invertebrates, based on an orchestrated action of humoral and cellular immune responses. The direct antimicrobial defense in ticks is accomplished by a variety of small molecules such as defensins, lysozymes or by tick-specific antimicrobial compounds such as microplusin/hebraein or 5.3-kDa family proteins. Phagocytosis of the invading microbes by tick hemocytes seems to be mediated by the primordial complement-like system composed of thioester-containing proteins, fibrinogen-related lectins and convertase-like factors. Moreover, an important role in survival of the ingested microbes seems to be played by host proteins and redox balance maintenance in the tick midgut. Here, we summarize recent knowledge about the major components of tick immune system and focus on their interaction with the relevant tick-transmitted pathogens, represented by spirochetes (Borrelia, rickettsiae (Anaplasma, and protozoans (Babesia. Availability of the tick genomic database and feasibility of functional genomics based on RNA interference greatly contribute to the understanding of molecular and cellular interplay at the tick-pathogen interface and may provide new targets for blocking the transmission of tick pathogens.

  12. Stem cell autotomy and niche interaction in different systems.

    Science.gov (United States)

    Dorn, David C; Dorn, August

    2015-07-26

    The best known cases of cell autotomy are the formation of erythrocytes and thrombocytes (platelets) from progenitor cells that reside in special niches. Recently, autotomy of stem cells and its enigmatic interaction with the niche has been reported from male germline stem cells (GSCs) in several insect species. First described in lepidopterans, the silkmoth, followed by the gipsy moth and consecutively in hemipterans, foremost the milkweed bug. In both, moths and the milkweed bug, GSCs form finger-like projections toward the niche, the apical cells (homologs of the hub cells in Drosophila). Whereas in the milkweed bug the projection terminals remain at the surface of the niche cells, in the gipsy moth they protrude deeply into the singular niche cell. In both cases, the projections undergo serial retrograde fragmentation with progressing signs of autophagy. In the gipsy moth, the autotomized vesicles are phagocytized and digested by the niche cell. In the milkweed bug the autotomized vesicles accumulate at the niche surface and disintegrate. Autotomy and sprouting of new projections appears to occur continuously. The significance of the GSC-niche interactions, however, remains enigmatic. Our concept on the signaling relationship between stem cell-niche in general and GSC and niche (hub cells and cyst stem cells) in particular has been greatly shaped by Drosophila melanogaster. In comparing the interactions of GSCs with their niche in Drosophila with those in species exhibiting GSC autotomy it is obvious that additional or alternative modes of stem cell-niche communication exist. Thus, essential signaling pathways, including niche-stem cell adhesion (E-cadherin) and the direction of asymmetrical GSC division - as they were found in Drosophila - can hardly be translated into the systems where GSC autotomy was reported. It is shown here that the serial autotomy of GSC projections shows remarkable similarities with Wallerian axonal destruction, developmental axon

  13. Stem cell autotomy and niche interaction in different systems

    Science.gov (United States)

    Dorn, David C; Dorn, August

    2015-01-01

    The best known cases of cell autotomy are the formation of erythrocytes and thrombocytes (platelets) from progenitor cells that reside in special niches. Recently, autotomy of stem cells and its enigmatic interaction with the niche has been reported from male germline stem cells (GSCs) in several insect species. First described in lepidopterans, the silkmoth, followed by the gipsy moth and consecutively in hemipterans, foremost the milkweed bug. In both, moths and the milkweed bug, GSCs form finger-like projections toward the niche, the apical cells (homologs of the hub cells in Drosophila). Whereas in the milkweed bug the projection terminals remain at the surface of the niche cells, in the gipsy moth they protrude deeply into the singular niche cell. In both cases, the projections undergo serial retrograde fragmentation with progressing signs of autophagy. In the gipsy moth, the autotomized vesicles are phagocytized and digested by the niche cell. In the milkweed bug the autotomized vesicles accumulate at the niche surface and disintegrate. Autotomy and sprouting of new projections appears to occur continuously. The significance of the GSC-niche interactions, however, remains enigmatic. Our concept on the signaling relationship between stem cell-niche in general and GSC and niche (hub cells and cyst stem cells) in particular has been greatly shaped by Drosophila melanogaster. In comparing the interactions of GSCs with their niche in Drosophila with those in species exhibiting GSC autotomy it is obvious that additional or alternative modes of stem cell-niche communication exist. Thus, essential signaling pathways, including niche-stem cell adhesion (E-cadherin) and the direction of asymmetrical GSC division - as they were found in Drosophila - can hardly be translated into the systems where GSC autotomy was reported. It is shown here that the serial autotomy of GSC projections shows remarkable similarities with Wallerian axonal destruction, developmental axon

  14. The role of interactive control systems in obtaining internal consistency in the management control system package

    DEFF Research Database (Denmark)

    Toldbod, Thomas; Israelsen, Poul

    2014-01-01

    Companies rely on multiple Management Control Systems to obtain their short and long term objectives. When applying a multifaceted perspective on Management Control System the concept of internal consistency has been found to be important in obtaining goal congruency in the company. However, to d...... management is aware of this shortcoming they use the cybernetic controls more interactively to overcome this shortcoming, whereby the cybernetic controls are also used as a learning platform and not just for performance control....

  15. Interaction of Plant Extracts with Central Nervous System Receptors

    Directory of Open Access Journals (Sweden)

    Kenneth Lundstrom

    2017-02-01

    Full Text Available Background: Plant extracts have been used in traditional medicine for the treatment of various maladies including neurological diseases. Several central nervous system receptors have been demonstrated to interact with plant extracts and components affecting the pharmacology and thereby potentially playing a role in human disease and treatment. For instance, extracts from Hypericum perforatum (St. John’s wort targeted several CNS receptors. Similarly, extracts from Piper nigrum, Stephania cambodica, and Styphnolobium japonicum exerted inhibition of agonist-induced activity of the human neurokinin-1 receptor. Methods: Different methods have been established for receptor binding and functional assays based on radioactive and fluorescence-labeled ligands in cell lines and primary cell cultures. Behavioral studies of the effect of plant extracts have been conducted in rodents. Plant extracts have further been subjected to mood and cognition studies in humans. Results: Mechanisms of action at molecular and cellular levels have been elucidated for medicinal plants in support of standardization of herbal products and identification of active extract compounds. In several studies, plant extracts demonstrated affinity to a number of CNS receptors in parallel indicating the complexity of this interaction. In vivo studies showed modifications of CNS receptor affinity and behavioral responses in animal models after treatment with medicinal herbs. Certain plant extracts demonstrated neuroprotection and enhanced cognitive performance, respectively, when evaluated in humans. Noteworthy, the penetration of plant extracts and their protective effect on the blood-brain-barrier are discussed. Conclusion: The affinity of plant extracts and their isolated compounds for CNS receptors indicates an important role for medicinal plants in the treatment of neurological disorders. Moreover, studies in animal and human models have confirmed a scientific basis for the

  16. Introduction to a Protein Interaction System Used for Quantitative Evaluation of Biomolecular Interactions

    OpenAIRE

    Yamniuk, Aaron

    2013-01-01

    A central goal of molecular biology is the determination of biomolecular function. This comes largely from a knowledge of the non-covalent interactions that biological small and macro-molecules experience. The fundamental mission of the Molecular Interactions Research Group (MIRG) of the ABRF is to show how solution biophysical tools are used to quantitatively characterize molecular interactions, and to educate the ABRF members and scientific community on the utility and limitations of core t...

  17. Interactions in Natural Colloid Systems "Biosolids" - Soil and Plant

    Science.gov (United States)

    Kalinichenko, Kira V.; Nikovskaya, Galina N.; Ulberg, Zoya R.

    2016-04-01

    The "biosolids" are complex biocolloid system arising in huge amounts (mln tons per year) from biological municipal wastewater treatment. These contain clusters of nanoparticles of heavy metal compounds (in slightly soluble or unsoluble forms, such as phosphates, sulphates, carbonates, hydroxides, and etc.), cells, humic substances and so on, involved in exopolysaccharides (EPS) net matrix. One may consider that biosolids are the natural nanocomposite. Due to the presence of nitrogen, phosphorus, potassium and other macro- and microelements (heavy metals), vitamins, aminoacids, etc., the biosolids are a depot of bioelements for plant nutrition. Thus, it is generally recognized that most rationally to utilize them for land application. For this purpose the biocolloid process was developed in biosolids system by initiation of microbial vital ability followed by the synthesis of EPS, propagation of ecologically important microorganisms, loosening of the structure and weakening of the coagulation contacts between biosolids colloids, but the structure integrity maintaining [1,2]. It was demonstrated that the applying of biosolids with metabolizing microorganisms to soil provided the improving soil structure, namely the increasing of waterstable aggregates content (70% vs. 20%). It occurs due to flocculation ability of biosolids EPS. The experimental modelling of mutual interactions in systems of soils - biosolids (with metabolizing microorganisms) were realized and their colloid and chemical mechanisms were formulated [3]. As it is known, the most harmonious plant growth comes at a prolonged entering of nutrients under the action of plant roots exudates which include pool of organic acids and polysaccharides [4]. Special investigations showed that under the influence of exudates excreted by growing plants, the biosolids microelements can release gradually from immobilized state into environment and are able to absorb by plants. Thus, the biosolids can serve as an active

  18. COTHERM: Modelling fluid-rock interactions in Icelandic geothermal systems

    Science.gov (United States)

    Thien, Bruno; Kosakowski, Georg; Kulik, Dmitrii

    2014-05-01

    field by Gudmundsson & Arnorsson [3] and by Icelandic partners of the COTHERM project suggests that the concept of partial equilibrium with instantaneous precipitation of secondary minerals is not sufficient to satisfactorily describe the experimental data. Considering kinetic controls also for secondary minerals appears as indispensable to properly describe the geothermal system evolution using a reactive transport modelling approach [4]. [1] Kulik D.A., Wagner T., Dmytrieva S.V., Kosakowski G., Hingerl F.F., Chudnenko K.V., Berner U., 2013. GEM-Selektor geochemical modeling package: revised algorithm and GEMS3K numerical kernel for coupled simulation codes. Computational Geosciences 17, 1-24. http://gems.web.psi.ch. [2] Palandri, J.L., Kharaka, Y.K., 2004. A compilation of rate parameters of water-mineral interaction kinetics for application to geochemical modelling. U.S.Geological Survey, Menlo Park, CA, pp. 1-64. [3] Gudmundsson B.T., Arnorsson S., 2005. Secondary mineral-fluid equilibria in the Krafla and Namafjall geothermal systems, Iceland. Applied Geochememistry 20, 1607-1625. [4] Kosakowski, G., & Watanabe, N., 2013. OpenGeoSys-Gem: A numerical tool for calculating geochemical and porosity changes in saturated and partially saturated media. Physics and Chemistry of the Earth, Parts A/B/C. doi:10.1016/j.pce.2013.11.008

  19. Preliminary investigation of interconnected systems interactions for the safety injection system of Indian Point-3

    International Nuclear Information System (INIS)

    Alesso, H.P.; Lappa, D.A.; Smith, C.F.; Sacks, I.J.

    1983-01-01

    The rich diversity of ideas and techniques for analyzing interconnected systems interaction has presented the NRC with the problem of identifying methods appropriate for their own review and audit. This report presents the findings of a preliminary study using the Digraph Matrix Analysis method to evaluate interconnected systems interactions for the safety injection system of Indian Point-3. The analysis effort in this study was subjected to NRC constraints regarding the use of Boolean logic, the construction of simplified plant representations or maps, and the development of heuristic measures as specified by the NRC. The map and heuristic measures were found to be an unsuccessful approach. However, from the effort to model and analyze the Indian Point-3 safety injection system, including Boolean logic in the model, singleton and doubleton cut-sets were identified. It is recommended that efforts excluding Boolean logic and utilizing the NRC heuristic measures not be pursed further and that the Digraph Matrix approach (or other comparable risk assessment technique) with Boolean logic included to conduct the audit of the Indian Point-3 systems interaction study

  20. Entropy and Recurrence Measures of a Financial Dynamic System by an Interacting Voter System

    Directory of Open Access Journals (Sweden)

    Hong-Li Niu

    2015-04-01

    Full Text Available A financial time series agent-based model is reproduced and investigated by the statistical physics system, the finite-range interacting voter system. The voter system originally describes the collective behavior of voters who constantly update their positions on a particular topic, which is a continuous-time Markov process. In the proposed model, the fluctuations of stock price changes are attributed to the market information interaction amongst the traders and certain similarities of investors’ behaviors. Further, the complexity of return series of the financial model is studied in comparison with two real stock indexes, the Shanghai Stock Exchange Composite Index and the Hang Seng Index, by composite multiscale entropy analysis and recurrence analysis. The empirical research shows that the simulation data for the proposed model could grasp some natural features of actual markets to some extent.

  1. The influence of system interactivity and technical support on learning management system utilization

    Directory of Open Access Journals (Sweden)

    Sousan Baleghi-Zadeh

    2017-03-01

    Full Text Available In recent years, there has been a growing increase in using Learning Management System (LMS by universities. However, its utilization by students is limited in Malaysia. The main purpose of the present study is to develop and test a model that predicts LMS utilization by Malaysian higher education students. Based on the Technology Acceptance Model, the study investigated the relationships among six constructs (system interactivity, technical support, perceived ease of use, perceived usefulness, behavioral intention to use and LMS use through structural equation modelling. The participants were 216 undergraduate students from a local university in Malaysia. The result of the study revealed that system interactivity had a significant effect on perceived usefulness, but not on perceived ease of use; technical support had a significant effect on perceived ease of use, but not on perceived usefulness.

  2. A novel interactive educational system in the operating room--the IE system.

    Science.gov (United States)

    Nakayama, Takayuki; Numao, Noboru; Yoshida, Soichiro; Ishioka, Junichiro; Matsuoka, Yoh; Saito, Kazutaka; Fujii, Yasuhisa; Kihara, Kazunori

    2016-02-02

    The shortage of surgeon is one of the serious problems in Japan. To solve the problem, various efforts have been undertaken to improve surgical education and training. However, appropriate teaching methods in the operating room have not been well established. The aim of this study is to assess the utility of a novel interactive educational (IE) system for surgical education on urologic surgeries in the operating room. A total of 20 Japanese medical students were educated on urologic surgery using the IE system in the operating room. The IE system consists of two parts. The first is three-dimensional (3D) magnified vision of the operative field using a 3D head-mounted display and a 3D endoscope. The second is interactive educative communication between medical students and surgeons using a small-sized wireless communication device. The satisfaction level with the IE system and the physical burden on medical students was examined via questionnaire. All students utilized the IE system in urologic surgery and responded to the survey. Most students were satisfied with the IE system. They also felt more welcomed by the surgeon when using the IE system than when not using it. No major unpleasant symptoms were observed but five students (25 %) experienced mild eye fatigue as a result of viewing the medical images. The IE system has the potential to motivate students to become interested in surgery and could be an efficient method of surgical education in the operating room.

  3. Each to his own: how different users call for different interaction methods in recommender systems

    NARCIS (Netherlands)

    Knijnenburg, B.P.; Reijmer, N.J.M.; Willemsen, M.C.; Mobasher, B.; Burke, R.

    2011-01-01

    This paper compares five different ways of interacting with an attribute-based recommender system and shows that different types of users prefer different interaction methods. In an online experiment with an energy-saving recommender system the interaction methods are compared in terms of perceived

  4. Deep-Sea Hydrothermal Vent Viruses Compensate for Microbial Metabolism in Virus-Host Interactions.

    Science.gov (United States)

    He, Tianliang; Li, Hongyun; Zhang, Xiaobo

    2017-07-11

    Viruses are believed to be responsible for the mortality of host organisms. However, some recent investigations reveal that viruses may be essential for host survival. To date, it remains unclear whether viruses are beneficial or harmful to their hosts. To reveal the roles of viruses in the virus-host interactions, viromes and microbiomes of sediment samples from three deep-sea hydrothermal vents were explored in this study. To exclude the influence of exogenous DNAs on viromes, the virus particles were purified with nuclease (DNase I and RNase A) treatments and cesium chloride density gradient centrifugation. The metagenomic analysis of viromes without exogenous DNA contamination and microbiomes of vent samples indicated that viruses had compensation effects on the metabolisms of their host microorganisms. Viral genes not only participated in most of the microbial metabolic pathways but also formed branched pathways in microbial metabolisms, including pyrimidine metabolism; alanine, aspartate, and glutamate metabolism; nitrogen metabolism and assimilation pathways of the two-component system; selenocompound metabolism; aminoacyl-tRNA biosynthesis; and amino sugar and nucleotide sugar metabolism. As is well known, deep-sea hydrothermal vent ecosystems exist in relatively isolated environments which are barely influenced by other ecosystems. The metabolic compensation of hosts mediated by viruses might represent a very important aspect of virus-host interactions. IMPORTANCE Viruses are the most abundant biological entities in the oceans and have very important roles in regulating microbial community structure and biogeochemical cycles. The relationship between virus and host microbes is broadly thought to be that of predator and prey. Viruses can lyse host cells to control microbial population sizes and affect community structures of hosts by killing specific microbes. However, viruses also influence their hosts through manipulation of bacterial metabolism. We found

  5. Lateral dynamic interaction analysis of a train girder pier system

    Science.gov (United States)

    Xia, H.; Guo, W. W.; Wu, X.; Pi, Y. L.; Bradford, M. A.

    2008-12-01

    A dynamic model of a coupled train-girder-pier system is developed in this paper. Each vehicle in a train is modeled with 27 degrees-of-freedom for a 4-axle passenger coach or freight car, and 31 for a 6-axle locomotive. The bridge model is applicable to straight and curved bridges. The centrifugal forces of moving vehicles on curved bridges are considered in both the vehicle model and the bridge model. The dynamic interaction between the bridge and train is realized through an assumed wheel-hunting movement. A case study is performed for a test train traversing two straight and two curved multi-span bridges with high piers. The histories of the train traversing the bridges are simulated and the dynamic responses of the piers and the train vehicles are calculated. A field experiment is carried out to verify the results of the analysis, by which the lateral resonant train speed inducing the peak pier-top amplitudes and some other observations are validated.

  6. Drug/radiation interactions and central nervous system injury

    International Nuclear Information System (INIS)

    DeAngelis, L.M.; Shapiro, W.R.

    1991-01-01

    Central nervous system (CNS) injury caused by combined treatment with cranial radiation therapy (CRT) and chemotherapy is a complicated and difficult problem. Interactions between the two modalities at the cellular level, the effect of treatment sequencing, and chemotherapy and RT dosages are all poorly understood. While this is generally true and applicable to toxicities expressed in multiple organs and tissue types, it is particularly true for the brain. There are many clinical descriptions and situations that strongly implicate an enhanced neurotoxic potential for combined treatment compared to either therapy alone; there is a paucity of definitive experimental evidence, however, and few animal models that can be used to elucidate the nature and pathophysiology of this clinical association. This paper addresses the neurotoxic potential of a specific chemotherapeutic drug when combined with CRT; outlines whose drugs known to cause CNS injury when combined with CRT. Although many of the clinical situations are complicated because multiple cytotoxic agents have been used, usually only one is thought to contribute to the CNS injury. The authors discuss each drug separately

  7. Implementation of interactive virtual simulation of physical systems

    International Nuclear Information System (INIS)

    Sanchez, H; Escobar, J J; Gonzalez, J D; Beltran, J

    2014-01-01

    Considering the limited availability of laboratories for physics teaching and the difficulties this causes in the learning of school students in Santa Marta Colombia, we have developed software in order to generate greater student interaction with the phenomena physical and improve their understanding. Thereby, this system has been proposed in an architecture Model/View- View- Model (MVVM), sharing the benefits of MVC. Basically, this pattern consists of 3 parts: The Model, that is responsible for business logic related. The View, which is the part with which we are most familiar and the user sees. Its role is to display data to the user and allowing manipulation of the data of the application. The ViewModel, which is the middle part of the Model and the View (analogous to the Controller in the MVC pattern), as well as being responsible for implementing the behavior of the view to respond to user actions and expose data model in a way that is easy to use links to data in the view. .NET Framework 4.0 and editing package Silverlight 4 and 5 are the main requirements needed for the deployment of physical simulations that are hosted in the web application and a web browser (Internet Explorer, Mozilla Firefox or Chrome). The implementation of this innovative application in educational institutions has shown that students improved their contextualization of physical phenomena

  8. A generalized coherence framework for detecting and characterizing nonlinear interactions in the nervous system

    NARCIS (Netherlands)

    Yang, Y.; Solis Escalante, T.; van der Helm, F.C.T.; Schouten, A.C.

    2016-01-01

    Objective: This paper introduces a generalized coherence framework for detecting and characterizing nonlinear interactions in the nervous system, namely cross-spectral coherence (CSC). CSC can detect different types of nonlinear interactions including harmonic and intermodulation coupling as present

  9. INTERACTION ANALYSIS AS A FEEDBACK SYSTEM IN TEACHER PREPARATION.

    Science.gov (United States)

    AMIDON, EDMUND; POWELL, EVAN

    FOUR GROUPS OF 15 STUDENT TEACHERS EACH WERE USED TO TEST THE HYPOTHESIS THAT (A) THOSE TAUGHT INTERACTION ANALYSIS WOULD BE MORE INDIRECT (ACCEPTING OF PUPIL FEELINGS AND IDEAS, ENCOURAGING, QUESTIONING) AT THE END OF STUDENT TEACHING THAN THOSE TAUGHT LEARNING THEORY, AND (B) AMONG THOSE TAUGHT INTERACTION ANALYSIS, THOSE SUPERVISED BY…

  10. Detection of Protein Interactions in T3S Systems Using Yeast Two-Hybrid Analysis.

    Science.gov (United States)

    Nilles, Matthew L

    2017-01-01

    Two-hybrid systems, sometimes termed interaction traps, are genetic systems designed to find and analyze interactions between proteins. The most common systems are yeast based (commonly Saccharomyces cerevisae) and rely on the functional reconstitution of the GAL4 transcriptional activator. Reporter genes, such as the lacZ gene of Escherichia coli (encodes β-galactosidase), are placed under GAL4-dependent transcriptional control to provide quick and reliable detection of protein interactions. In this method the use of a yeast-based two-hybrid system is described to study protein interactions between components of type III secretion systems.

  11. Analysis of User Requirements in Interactive 3D Video Systems

    Directory of Open Access Journals (Sweden)

    Haiyue Yuan

    2012-01-01

    Full Text Available The recent development of three dimensional (3D display technologies has resulted in a proliferation of 3D video production and broadcasting, attracting a lot of research into capture, compression and delivery of stereoscopic content. However, the predominant design practice of interactions with 3D video content has failed to address its differences and possibilities in comparison to the existing 2D video interactions. This paper presents a study of user requirements related to interaction with the stereoscopic 3D video. The study suggests that the change of view, zoom in/out, dynamic video browsing, and textual information are the most relevant interactions with stereoscopic 3D video. In addition, we identified a strong demand for object selection that resulted in a follow-up study of user preferences in 3D selection using virtual-hand and ray-casting metaphors. These results indicate that interaction modality affects users’ decision of object selection in terms of chosen location in 3D, while user attitudes do not have significant impact. Furthermore, the ray-casting-based interaction modality using Wiimote can outperform the volume-based interaction modality using mouse and keyboard for object positioning accuracy.

  12. Sensory Systems and Environmental Change on Behavior during Social Interactions

    Directory of Open Access Journals (Sweden)

    S. M. Bierbower

    2013-01-01

    Full Text Available The impact of environmental conditions for transmitting sensory cues and the ability of crayfish to utilize olfaction and vision were examined in regards to social interactive behavior. The duration and intensity of interactions were examined for conspecific crayfish with different sensory abilities. Normally, vision and chemosensory have roles in agonistic communication of Procambarus clarkii; however, for the blind cave crayfish (Orconectes australis packardi, that lack visual capabilities, olfaction is assumed to be the primary sensory modality. To test this, we paired conspecifics in water and out of water in the presence and absence of white light to examine interactive behaviors when these various sensory modalities are altered. For sighted crayfish, in white light, interactions occurred and escalated; however, when the water was removed, interactions and aggressiveness decreased, but, there was an increase in visual displays out of the water. The loss of olfaction abilities for blind cave and sighted crayfish produced fewer social interactions. The importance of environmental conditions is illustrated for social interactions among sighted and blind crayfish. Importantly, this study shows the relevance in the ecological arena in nature for species survival and how environmental changes disrupt innate behaviors.

  13. TIGER: A graphically interactive grid system for turbomachinery applications

    Science.gov (United States)

    Shih, Ming-Hsin; Soni, Bharat K.

    1992-01-01

    Numerical grid generation algorithm associated with the flow field about turbomachinery geometries is presented. Graphical user interface is developed with FORMS Library to create an interactive, user-friendly working environment. This customized algorithm reduces the man-hours required to generate a grid associated with turbomachinery geometry, as compared to the use of general-purpose grid generation softwares. Bezier curves are utilized both interactively and automatically to accomplish grid line smoothness and orthogonality. Graphical User Interactions are provided in the algorithm, allowing the user to design and manipulate the grid lines with a mouse.

  14. Observation of Subdiffusion in a Disordered Interacting System

    International Nuclear Information System (INIS)

    Lucioni, E.; Deissler, B.; Tanzi, L.; Roati, G.; Zaccanti, M.; Inguscio, M.; Modugno, G.; Modugno, M.; Larcher, M.; Dalfovo, F.

    2011-01-01

    We study the transport dynamics of matter-waves in the presence of disorder and nonlinearity. An atomic Bose-Einstein condensate that is localized in a quasiperiodic lattice in the absence of atom-atom interaction shows instead a slow expansion with a subdiffusive behavior when a controlled repulsive interaction is added. The measured features of the subdiffusion are compared to numerical simulations and a heuristic model. The observations confirm the nature of subdiffusion as interaction-assisted hopping between localized states and highlight a role of the spatial correlation of the disorder.

  15. Aromatic-Aromatic Interactions in Biological System: Structure Activity Relationships

    International Nuclear Information System (INIS)

    Rajagopal, Appavu; Deepa, Mohan; Govindaraju, Munisamy

    2016-01-01

    While, intramolecular hydrogen bonds have attracted the greatest attention in studies of peptide conformations, the recognition that several other weakly polar interactions may be important determinants of folded structure has been growing. Burley and Petsko provided a comprehensive overview of the importance of weakly polar interactions, in shaping protein structures. The interactions between aromatic rings, which are spatially approximate, have attracted special attention. A survey of the proximal aromatic residue pairs in proteins, allowed Burley and Petsko to suggest that, “phenyl ring centroids are separated by a preferential distance of between 4.5 and 7 Å, and dihedral angles approximately 90° are most common”

  16. Aromatic-Aromatic Interactions in Biological System: Structure Activity Relationships

    Energy Technology Data Exchange (ETDEWEB)

    Rajagopal, Appavu; Deepa, Mohan [Molecular Biophysics Unit, Indian Institute of Sciences-Bangalore, Karnataka (India); Govindaraju, Munisamy [Bio-Spatial Technology Research Unit, Department of Environmental Biotechnology, School of Environmental Sciences, Bharathidasan University, Tiruchirappalli, Tamil Nadu (India)

    2016-02-26

    While, intramolecular hydrogen bonds have attracted the greatest attention in studies of peptide conformations, the recognition that several other weakly polar interactions may be important determinants of folded structure has been growing. Burley and Petsko provided a comprehensive overview of the importance of weakly polar interactions, in shaping protein structures. The interactions between aromatic rings, which are spatially approximate, have attracted special attention. A survey of the proximal aromatic residue pairs in proteins, allowed Burley and Petsko to suggest that, “phenyl ring centroids are separated by a preferential distance of between 4.5 and 7 Å, and dihedral angles approximately 90° are most common”.

  17. A data seamless interaction scheme between electric power secondary business systems

    Science.gov (United States)

    Ai, Wenkai; Qian, Feng

    2018-03-01

    At present, the data interaction of electric power secondary business systems is very high, and it is not universal to develop programs when data interaction is carried out by different manufacturers' electric power secondary business systems. There are different interaction schemes for electric power secondary business systems with different manufacturers, which lead to high development cost, low reusability and high maintenance difficulty. This paper introduces a new data seamless interaction scheme between electric power secondary business systems. The scheme adopts the international common Java message service protocol as the transmission protocol, adopts the common JavaScript object symbol format as the data interactive format, unified electric power secondary business systems data interactive way, improve reusability, reduce complexity, monitor the operation of the electric power secondary business systems construction has laid a solid foundation.

  18. Interaction between systems and software engineering in safety-critical systems

    International Nuclear Information System (INIS)

    Knight, J.

    1994-01-01

    There are three areas of concern: when is software to be considered safe; what, exactly, is the role of the software engineer; and how do systems, or sometimes applications, engineers and software engineers interact with each other. The author presents his perspective on these questions which he feels differ from those of many in the field. He argues for a clear definition of safety in the software arena, so the engineer knows what he is engineering toward. Software must be viewed as part of the entire system, since it does not function on its own, or isolation. He argues for the establishment of clear specifications in this area

  19. INTERACT

    DEFF Research Database (Denmark)

    Jochum, Elizabeth; Borggreen, Gunhild; Murphey, TD

    This paper considers the impact of visual art and performance on robotics and human-computer interaction and outlines a research project that combines puppetry and live performance with robotics. Kinesics—communication through movement—is the foundation of many theatre and performance traditions ...

  20. An interactive web-based extranet system model for managing ...

    African Journals Online (AJOL)

    ... objectives for students, lecturers and parents to access and compute results ... The database will serve as repository of students' academic records over a ... Keywords: Extranet-Model, Interactive, Web-Based, Students, Academic, Records ...

  1. Interaction between propulsion and levitation system in the HTSC-permanent magnet conveyance system

    International Nuclear Information System (INIS)

    Ohashi, S.; Nishio, R.; Hashikawa, T.

    2010-01-01

    The magnetically levitated conveyance system has been developed. Pinning force of high temperature bulk superconductors (HTSC) are used for the levitation and the guidance of the carrier. The magnetic rail is set on the ground, and flux from the magnetic rail is pinned by HTSCs on the carrier body. To increase the load weight, the repulsive force of the permanent magnet is introduced. The hybrid levitation system is composed. The repulsive force by the permanent magnet between the load stage on the carrier and the magnetic rail on the ground is used to support the load weight. As the load stage is connected to the carrier body by the linear sliders, the mass of the load weight does not act on the carrier body. The interaction between the electromagnet and the permanent magnet under the load stage generates the propulsion force. The electromagnet is constructed by the air core coils, and excited only when the load stage passes. The interaction between the propulsion and the levitation system is investigated. Disturbance of the propulsion system on the levitation and the guidance force is measured. The results show the influence of the propulsion electromagnet on the pinning force is little, and this propulsion system works effectively.

  2. Interaction between propulsion and levitation system in the HTSC-permanent magnet conveyance system

    Energy Technology Data Exchange (ETDEWEB)

    Ohashi, S., E-mail: ohashi@ipcku.kanasi-u.ac.j [Kansai University 3-3-35, Yamate-cho, Suita, Osaka 564-8680 (Japan); Nishio, R.; Hashikawa, T. [Kansai University 3-3-35, Yamate-cho, Suita, Osaka 564-8680 (Japan)

    2010-11-01

    The magnetically levitated conveyance system has been developed. Pinning force of high temperature bulk superconductors (HTSC) are used for the levitation and the guidance of the carrier. The magnetic rail is set on the ground, and flux from the magnetic rail is pinned by HTSCs on the carrier body. To increase the load weight, the repulsive force of the permanent magnet is introduced. The hybrid levitation system is composed. The repulsive force by the permanent magnet between the load stage on the carrier and the magnetic rail on the ground is used to support the load weight. As the load stage is connected to the carrier body by the linear sliders, the mass of the load weight does not act on the carrier body. The interaction between the electromagnet and the permanent magnet under the load stage generates the propulsion force. The electromagnet is constructed by the air core coils, and excited only when the load stage passes. The interaction between the propulsion and the levitation system is investigated. Disturbance of the propulsion system on the levitation and the guidance force is measured. The results show the influence of the propulsion electromagnet on the pinning force is little, and this propulsion system works effectively.

  3. Critical dynamics of an interacting magnetic nanoparticle system

    DEFF Research Database (Denmark)

    Hansen, Mikkel Fougt; Jonsson, P.E.; Nordblad, P.

    2002-01-01

    Effects of dipole-dipole interactions on the magnetic relaxation have been investigated for three Fe-C nanoparticle samples with volume concentrations of 0.06, 5 and 17 vol%. While both the 5 and 17 vol% samples exhibit collective behaviour due to dipolar interactions, only the 17 vol% sample dis...... displays critical behaviour close to its transition temperature. The behaviour of the 5 vol% sample can be attributed to a mixture of collective and single-particle dynamics....

  4. An Interactive Virtual Reality System for On-Orbit Servicing

    OpenAIRE

    Sagardia, Mikel; Hertkorn, Katharina; Hulin, Thomas; Wolff, Robin; Hummel, Johannes; Dodiya, Janki; Gerndt, Andreas

    2013-01-01

    The growth of space debris is becoming a serious problem. There is an urgent need for mitigation measures based on maintenance, repair and de-orbiting technologies. Our video presents a virtual reality framework in which robotic maintenance tasks of satellites can be simulated interactively. The two key components of this framework are a realistic virtual reality simulation and an immersive interaction device. The peculiarity of the virtual reality simulation is the combi...

  5. The Effects of Interactions between Management Control Systems and Strategy on Firm Performance: An Empirical Study

    OpenAIRE

    Melek Eker; Semih Eker

    2016-01-01

    In recent years, there has been growing interest in examining the relationships among management control systems, business strategy and firm performance. In this study, the interactions of management control systems and strategy with their impact on firm performance are examined with an empirical analysis, based on the data from 94 manufacturing firms from the top 500 in Turkey in 2014. The results support the postulate that high interaction between interactive control system (ICS) and differ...

  6. Mechanism of the Interaction of Cannabinoid System in Central Amygdale with Opioid System

    Directory of Open Access Journals (Sweden)

    S. Sarahroodi

    2008-01-01

    Full Text Available Background and objectivesCannabinoids which are active compounds of marijuana show some pharmacological effects similar to the opioids. There are also functional interactions between both cannabinoid and opioid systems. In this study we investigated the role of cannabinoid receptors in central amygdala and its interaction with opioid system.MethodsIn the present study, we investigated the effects of intraperitoneal injection of opioid drugs on response-induced by intra-amygdala (intra-Amyg microinjection of cannabinoid agents in rats, using elevated plus-maze test of anxiety. ResultsIntraperitoneal injection of morphine (3, 6 and 9 mg/kg increased %OAT and %OAE, but not locomotor activity, showing an anxiolytic response. However, some doses of the opioid receptor antagonist, naloxone reduced %OAT and locomotor activity as well. Intra-Amyg administration of CB1 cannabinoid receptor agonist, ACPA (at the dose of 1.25 and 5 ng/rat increased %OAT and %OAE but not locomotor activity, thus showing an anxiolytic response, which was increased by morphine (6 mg/kg, i.p. without any interaction. Naloxone also reduced ACPA effects. Intra-Amyg administration of CB1 cannabinoid receptor antagonist, AM251 (2.5, 25 and 100 ng/rat did not alter %OAT and %OAE but higher doses of drug (25 and 100 ng/rat reduced locomotor activity. However, the drug in combination of morphine anxiolytic response and with naloxone decreased anxiety.ConclusionThe results may indicate an anxiolytic for CB1 cannabinoid. Our results also showed that opioid system may have interaction with cannabinoid receptor in the amygdale. Keywords: Cannabinoids, Morphine; Naloxone, Anxiety, Elevated Plus-Maze

  7. Marital conflict and children's externalizing behavior: interactions between parasympathetic and sympathetic nervous system activity

    National Research Council Canada - National Science Library

    El-Sheikh, Mona; Beauchaine, Theodore P; Moore, Ginger A

    2009-01-01

    "Toward greater specificity in the prediction of externalizing problems in the context of interparental conflict, interactions between children's parasympathetic and sympathetic nervous system (PNS and SNS...

  8. Interaction, coalescence, and collapse of localized patterns in a quasi-one-dimensional system of interacting particles

    Science.gov (United States)

    Dessup, Tommy; Coste, Christophe; Saint Jean, Michel

    2017-01-01

    We study the path toward equilibrium of pairs of solitary wave envelopes (bubbles) that modulate a regular zigzag pattern in an annular channel. We evidence that bubble pairs are metastable states, which spontaneously evolve toward a stable single bubble. We exhibit the concept of topological frustration of a bubble pair. A configuration is frustrated when the particles between the two bubbles are not organized in a modulated staggered row. For a nonfrustrated (NF) bubble pair configuration, the bubbles interaction is attractive, whereas it is repulsive for a frustrated (F) configuration. We describe a model of interacting solitary wave that provides all qualitative characteristics of the interaction force: It is attractive for NF systems and repulsive for F systems and decreases exponentially with the bubbles distance. Moreover, for NF systems, the bubbles come closer and eventually merge as a single bubble, in a coalescence process. We also evidence a collapse process, in which one bubble shrinks in favor of the other one, overcoming an energetic barrier in phase space. This process is relevant for both NF systems and F systems. In NF systems, the coalescence prevails at low temperature, whereas thermally activated jumps make the collapse prevail at high temperature. In F systems, the path toward equilibrium involves a collapse process regardless of the temperature.

  9. The Interaction Systems Generated by the Teacher's Didactic Imprinting

    Science.gov (United States)

    Peralta, Nadia S.; Roselli, Néstor D.

    2015-01-01

    The current study aimed to identify and analyze the systems of interaction implemented by teachers in university classes, based on their teaching imprints. It focused on the interactions occurred in scholar natural contexts and the construction of knowledge based on said interaction. A form to observe the different behaviors was designed in order…

  10. Effect of pairwise dipole–dipole interaction among three-atom systems

    Indian Academy of Sciences (India)

    2014-07-18

    Jul 18, 2014 ... We present an analysis of a system of three two-level atoms interacting with one another through dipole–dipole interaction. The interaction manifests between the excited state of one of the atoms and the ground state of its nearest neighbour. Steady-state populations of the density matrix elements are ...

  11. Weak interaction contribution to the energy spectrum of two-lepton system

    International Nuclear Information System (INIS)

    Martynenko, A.P.; Saleev, V.A.

    1995-01-01

    The contribution of neutral currents to the weak interaction quasi-potential of two leptons is investigated. The exact expression for the weak interaction operator of the system for arbitrary biding energies in one-boson approximation is obtained. The weak interaction contribution to the S-levels displacement of hydrogen-like atom. 14 refs

  12. A tool for monitoring lecturers’ interactions with Learning Management Systems

    Directory of Open Access Journals (Sweden)

    Magdalena Cantabella

    2016-12-01

    Full Text Available Learning Management Systems’ (LMS interaction mechanisms are mainly focused on the improvement of students’ experiences and academic results. However, special attention should also be given to the interaction between these LMS and other actors involved in the educational process. This paper specifically targets the interaction of degree coordinators with LMS when monitoring lecturers’ performance, especially in an online mode. The methodology is guided by the following three objectives: (1 analysis of the limitations of monitoring lecturers in current LMS; (2 development of software program to overcome such limitations; and (3 empirical evaluation of the proposed program. The results show that this type of tool helps coordinators to intuitively and efficiently analyze the status of the subjects taught in their degree programs.

  13. Storytelling in Interactive 3D Geographic Visualization Systems

    Directory of Open Access Journals (Sweden)

    Matthias Thöny

    2018-03-01

    Full Text Available The objective of interactive geographic maps is to provide geographic information to a large audience in a captivating and intuitive way. Storytelling helps to create exciting experiences and to explain complex or otherwise hidden relationships of geospatial data. Furthermore, interactive 3D applications offer a wide range of attractive elements for advanced visual story creation and offer the possibility to convey the same story in many different ways. In this paper, we discuss and analyze storytelling techniques in 3D geographic visualizations so that authors and developers working with geospatial data can use these techniques to conceptualize their visualization and interaction design. Finally, we outline two examples which apply the given concepts.

  14. Memory systems interaction in the pigeon: working and reference memory.

    Science.gov (United States)

    Roberts, William A; Strang, Caroline; Macpherson, Krista

    2015-04-01

    Pigeons' performance on a working memory task, symbolic delayed matching-to-sample, was used to examine the interaction between working memory and reference memory. Reference memory was established by training pigeons to discriminate between the comparison cues used in delayed matching as S+ and S- stimuli. Delayed matching retention tests then measured accuracy when working and reference memory were congruent and incongruent. In 4 experiments, it was shown that the interaction between working and reference memory is reciprocal: Strengthening either type of memory leads to a decrease in the influence of the other type of memory. A process dissociation procedure analysis of the data from Experiment 4 showed independence of working and reference memory, and a model of working memory and reference memory interaction was shown to predict the findings reported in the 4 experiments. (PsycINFO Database Record (c) 2015 APA, all rights reserved).

  15. SNAPP: GRAPHING STUDENT INTERACTIONS IN A LEARNING MANAGEMENT SYSTEM

    Directory of Open Access Journals (Sweden)

    Kevin YEE,

    2011-01-01

    Full Text Available One of the more vexing problems in teaching fully-online classes concerns the development of community. As Rovai (2001 identified, online courses must combat feelings of isolation and impart a sense of personal and individual attention. To create a sense of belonging and togetherness, instructors typically need to surmount numerous technological hurdles inherent in online delivery, not least of which is the inescapable conclusion that the one factor most basic to the formation of community-face to face interaction-is by definition absent in an online class. Many new tech-based teaching tools have been developed in an attempt to ameliorate the digital alienation and promote interaction, such as discussion boards, synchronous chat rooms, and emerging media like wikis, blogs and podcasts, as well as virtual worlds, such as Second Life. As the frequency of interaction grows, so does the sense of belonging to a learning community (Dawson, 2008.

  16. Magnetostatic interactions in a natural magnetite-ulvospinel intergrowth system

    Science.gov (United States)

    Evans, M. E.; Krasa, D.; Williams, W.; Winklhofer, M.

    2005-12-01

    The difficult problem of magnetostatic interactions in naturally-occurring minerals has a long history but a renewed attack on it is currently being driven by recent advances in instrumentation and computing power. We report a new investigation of a finely exsolved magnetite/ulvöspinel intergrowth first studied magnetically by Evans & Wayman (1974) and more recently by Harrison et al. (2002). Transmission electron micrographs reveal a rectilinear pattern of tiny magnetite blocks separated by ulvöspinel sheets. The magnetite blocks have a gaussian size distribution with mean and standard deviation of 193 and 46 nm, respectively (n ~ 500), with the separation between nearest neighbours being typically 40 nm, but often much less. Thermomagnetic analysis yields a well-defined Curie point of 548°C indicating that the ``magnetite" actually has a compostion of Fe2.9Ti0.1O4. Routine hysteresis measurements immediately reflect the interaction between neighbouring ``magnetite" regions, with Mrs/Ms = 0.22, well below the expected value for non-interacting single-domain particles. The corresponding FORC diagram clearly reveals the interaction fields with Hi = 30 mT (full-width at half-maximum, FWHM) centred on a well-defined Hc peak at 20 mT. Furthermore, the maximum interaction field observed (~50 mT) agrees well with that expected from simple theory and micromagnetic calculations. Elimination of the intergrowth structure by heating in an evacuated quartz vial for 2 hours at 1000 °C leads to marked changes in the magnetic properties: Mrs/Ms drops to 0.11, Hcr/Hc increases from 1.98 to 2.73, the main peak on the FORC diagram shifts to 6 mT and the interaction field profile drastically narrows (FWHM Hi = 14 mT).

  17. Rice production systems and avian influenza: Interactions between mixed-farming systems, poultry and wild birds

    Science.gov (United States)

    Muzaffar, S.B.; Takekawa, John Y.; Prosser, D.J.; Newman, S.H.; Xiao, X.

    2010-01-01

    Wild waterfowl are the reservoir for avian influenza viruses (AIVs), a family of RNA viruses that may cause mild sickness in waterbirds. Emergence of H5N1, a highly pathogenic avian influenza (HPAI) strain, causing severe disease and mortality in wild birds, poultry and humans, had raised concerns about the role of wild birds in possible transmission of the disease. In this review, the link between rice production systems, poultry production systems, and wild bird ecology is examined to assess the extent to which these interactions could contribute towards the persistence and evolution of HPAI H5N1. The rice (Oryza sativa) and poultry production systems in Asia described, and then migration and movements of wild birds discussed. Mixed farming systems in Asia and wild bird movement and migration patterns create opportunities for the persistence of low pathogenic AIVs in these systems. Nonetheless, there is no evidence of long-term persistence of HPAI viruses (including the H5N1 subtype) in the wild. There are still significant gaps in the understanding of how AIVs circulate in rice systems. A better understanding of persistence of AIVs in rice farms, particularly of poultry origins, is essential in limiting exchange of AIVs between mixed-farming systems, poultry and wild birds.

  18. Development of the interactive model between Component Cooling Water System and Containment Cooling System using GOTHIC

    International Nuclear Information System (INIS)

    Byun, Choong Sup; Song, Dong Soo; Jun, Hwang Yong

    2006-01-01

    In a design point of view, component cooling water (CCW) system is not full-interactively designed with its heat loads. Heat loads are calculated from the CCW design flow and temperature condition which is determined with conservatism. Then the CCW heat exchanger is sized by using total maximized heat loads from above calculation. This approach does not give the optimized performance results and the exact trends of CCW system and the loads during transient. Therefore a combined model for performance analysis of containment and the component cooling water(CCW) system is developed by using GOTHIC software code. The model is verified by using the design parameters of component cooling water heat exchanger and the heat loads during the recirculation mode of loss of coolant accident scenario. This model may be used for calculating the realistic containment response and CCW performance, and increasing the ultimate heat sink temperature limits

  19. System dynamics model for environment - human systems interaction in the mining industry

    International Nuclear Information System (INIS)

    Pal, B.K.

    1994-01-01

    Use of advanced technology in the mining activities are polluting the natural environment, interfering with the normal life of the miners/residents. In this paper, health hazards due to underground workings and effect of environmental conditions on men are discussed. A composite system inter-relationship of the mining industries with the Government, society and environmental sectors is established. Allowing certain level of pollution, a system dynamics model is developed considering the parameters like more revenues from the mining industries, degradation of quality of life index - environmental index on long-term and short-term basis, new diseases due to pollution, social awareness, health care facilities, tax exemption etc. This model will help us to understand the optimisation of the parameters to establish the better interaction in the environment-human systems in the mining industries. 14 refs., 4 figs., 2 tabs

  20. LAIX-score : a design framework for live audience interaction management systems

    OpenAIRE

    Kuikkaniemi, Kai

    2017-01-01

    This study focuses on computer-supported live audience interaction. In conventional lectures audience interacts explicitly with the performer for example by waving hand and asking question directly or clapping hands. For decades, non digital audience response systems have enabled simple multiple option audience interaction patterns. Modern mobile personal computing devices, digital projectors, wireless networks and real time software platforms enable creation of new kinds of interaction patte...

  1. Nonequilibrium dynamics in an interacting Fe-C nanoparticle system

    DEFF Research Database (Denmark)

    Jönsson, P.; Hansen, Mikkel Fougt; Nordblad, P.

    2000-01-01

    Nonequilibrium dynamics in an interacting Fe-C nanoparticle sample, exhibiting a low-temperature spin-glass-like phase, has been studied by low-frequency ac susceptibility and magnetic relaxation experiments. The nonequilibrium behavior shows characteristic spin-glass features, but some qualitative...

  2. Host-pathogen interactions: A cholera surveillance system

    Energy Technology Data Exchange (ETDEWEB)

    Wright, Aaron T.

    2016-02-22

    Bacterial pathogen-secreted proteases may play a key role in inhibiting a potentially widespread host-pathogen interaction. Activity-based protein profiling enabled the identification of a major Vibrio cholerae serine protease that limits the ability of a host-derived intestinal lectin to bind to the bacterial pathogen in vivo.

  3. Interacting with molecular structures : user performance versus system complexity

    NARCIS (Netherlands)

    Liere, van R.; Martens, J.B.; Kok, A.J.F.; van Tienen, M.H.A.; Blach, R.; Kjems, E.

    2005-01-01

    Effective interaction in a virtual environment requires that the user can adequately judge the spatial relationships between the objects in a 3D scene. In order to accomplish adequate depth perception, existing virtual environments create useful perceptual cues through stereoscopy, motion parallax

  4. Electromagnetic interactions in relativistic systems of many bodies

    International Nuclear Information System (INIS)

    Cook, A.H.

    1987-09-01

    In a previous report (Cook, 1986, 1987) on a formulation of a quasi-relativistic quantum mechanical equation of motion for many particles, little was said of the electromagnetic interactions that keep a set of particles in a bound state. That omission is to some extent repaired in this report. (author). 3 refs

  5. Editorial: Expressive Interactive Systems That Tell a Story

    NARCIS (Netherlands)

    Reidsma, Dennis; Volpe, Gualtiero; Volpe, G; Camurri, A.; Camurri, Antonio; Nijholt, Antinus

    2015-01-01

    This special issue brings together selected, extended contributions from the Fourth Conference on Intelligent Technologies for Interactive Entertainment (INTETAIN 2011), with a special focus on research concerning the application of new technologies in the field of arts and culture. Since 2005, the

  6. Interactive Model-Centric Systems Engineering (IMCSE) Phase Two

    Science.gov (United States)

    2015-02-28

    109 Backend Implementation...as cell-phone GPS data offers unprecedented tracking of commuting, mobility , and navigation patterns within the urban environment. And yet many...Task 4 develops a service API to collect and query results across model executions. Task 5 implements the backend components to interact 160 Forio

  7. A description of the apparatus to be used in interaction experiments with the ABC laser system

    International Nuclear Information System (INIS)

    Caruso, A.; Strangio, M.; Andreoli, P.L.; Cerioni, I.; Di Paolo, A.; Di Virgilio, L.

    1988-01-01

    This report contains the part of the Frascati Laboratorio Fusione Laser activity related to the Apparatus (target chamber, position and alignement system, diagnostics) to be used in the interaction experiments with the ABC laser system

  8. INTERACTIVITY OF THE MODERN AUTOMATED SYSTEMS OF THE HELP TO THE DRIVER

    Directory of Open Access Journals (Sweden)

    Svetlana Alekseevna Vasyugova

    2017-09-01

    Full Text Available In this article the current technologies in the field of intelligent transportation systems are investigated. The latest systems on control of the safe movement on roads are considered. The analysis of the systems of the help to the driver implemented in cars is carried out. The system concept of the help to the driver of «System help» is offered. Algorithms of work of this system which is based on the principles of interactivity and interaction are investigated. By results of researches experiment on quality of work of system concept of «System help» is made.

  9. The potential of the system of interpersonal interaction in the formation of adolescent autonomy

    Directory of Open Access Journals (Sweden)

    Olga A. Dorontsova

    2015-12-01

    Full Text Available The paper discusses a significant and actual issue of developing autonomy of the individual. Special attention is paid to adolescent age having high potential for developing autonomy in view of certain changes in the psychological and social sphere of the adolescents. The value of interpersonal interaction in the course of developing adolescent autonomy is shown. The approaches to the concept of interaction are analyzed, four main directions of explaining the essence of interaction are allocated: symbolical interactionism (J. Mid, social exchange (J. Homans, G. Blumer, sociodramatic touch (E. Goffman transaction analysis (E. Berne. Types of interaction, efficiency of interaction development are considered. The analysis of interpersonal interaction issues shows its communication with the categories of «relation», «communication» and «joint activity» (B.G. Ananyev, G.M. Andreyeva, S.V. Dukhnovsky, Ya.L. Kolominsky V.N. Kunitsyna, V.N. Myasishchev, B.D. Parygin, etc.. The concept of interpersonal interaction system of the autonomy causing development of adolescence in the paradigm of psychologist-teacher interaction, and also child-parent interaction is described. The advantage of psychological assistance and pedagogical support within the system of interpersonal interaction for further development of adolescent autonomy is proved. The value of cooperation as one of the types of interpersonal interaction in the course of adolescent autonomy development is shown. Mechanisms of interpersonal interaction, nature of contact in interpersonal interaction, components of a social situation are described.

  10. Nuclear Energy and Renewables interaction: System Effects in Low-carbon Electricity Systems

    International Nuclear Information System (INIS)

    Keppler, Jan Horst; Cometto, Marco

    2013-01-01

    This report presents a synthesis of the OECD/NEA study 'Nuclear Energy and Renewables: System Effects in Low-carbon Electricity Systems'. It addresses the increasingly important interactions of variable renewables and dispatchable energy technologies, such as nuclear power, in terms of their effects on electricity systems. These effects add costs to the production of electricity, which are not usually transparent. The report recommends that decision-makers should take into account such system costs and internalise them according to a 'generator pays' principle, which is currently not the case. Analysing data from six OECD/NEA countries, the study finds that including the system costs of variable renewables at the level of the electricity grid increases the total costs of electricity supply by up to one-third, depending on technology, country and penetration levels. In addition, it concludes that, unless the current market subsidies for renewables are altered, dispatchable technologies will increasingly not be replaced as they reach their end of life and consequently security of supply will suffer. This implies that significant changes in management and cost allocation will be needed to generate the flexibility required for an economically viable coexistence of nuclear energy and renewables in increasingly de-carbonised electricity systems

  11. System engineering and automation an interactive educational approach

    CERN Document Server

    Fernandez de Canete, Javier; Garcia-Moral, Inmaculada

    2011-01-01

    This book provides insight and enhanced appreciation of analysis, modeling and control of dynamic systems. It presents realistic problems in order to analyze, design and develop automatic control systems.

  12. Method for designing networking adaptive interactive hybrid systems

    NARCIS (Netherlands)

    Kester, L. J.H.M.

    2010-01-01

    Advances in network technologies enable distributed systems, operating in complex physical environments, to co-ordinate their activities over larger areas within shorter time intervals. Some envisioned application domains for such systems are defence, crisis management, traffic management and public

  13. Creating networking adaptive interactive hybrid systems : A methodic approach

    NARCIS (Netherlands)

    Kester, L.J.

    2011-01-01

    Advances in network technologies enable distributed systems, operating in complex physical environments, to coordinate their activities over larger areas within shorter time intervals. Some envisioned application domains for such systems are defense, crisis management, traffic management, public

  14. Hyperspherical Treatment of Strongly-Interacting Few-Fermion Systems in One Dimension

    DEFF Research Database (Denmark)

    Volosniev, A. G.; Fedorov, D. V.; Jensen, A. S.

    2015-01-01

    We examine a one-dimensional two-component fermionic system in a trap, assuming that all particles have the same mass and interact through a strong repulsive zero-range force. First we show how a simple system of three strongly interacting particles in a harmonic trap can be treated using...

  15. Interaction systems design and the protocol- and middleware-centred paradigms in distributed application development

    NARCIS (Netherlands)

    Andrade Almeida, João; van Sinderen, Marten J.; Quartel, Dick; Ferreira Pires, Luis

    2003-01-01

    This paper aims at demonstrating the benefits and importance of interaction systems design in the development of distributed applications. We position interaction systems design with respect to two paradigms that have influenced the design of distributed applications: the middleware-centred and the

  16. Interactive and automated systems for nuclear track measurements with applications to fast neutron dosimetry

    International Nuclear Information System (INIS)

    Roberts, J.H.; Gold, R.; McNeece, J.P.; Preston, C.C.; Ruddy, F.H.

    1983-12-01

    Interactive and automatic track measuring systems have been developed primarily for fast neutron dosimetry in and around reactors. The interactive system is used for proton recoil measurements in nuclear research emulsions and the automatic systems for counting fission fragment tracks in Muscovite mica. The status of these systems, along with illustrative applications, are presented, particularly with regard to their relationship to neutron personnel dosimetry. 16 references, 12 figures

  17. A high-speed drug interaction search system for ease of use in the clinical environment.

    Science.gov (United States)

    Takada, Masahiro; Inada, Hiroshi; Nakazawa, Kazuo; Tani, Shoko; Iwata, Michiaki; Sugimoto, Yoshihisa; Nagata, Satoru

    2012-12-01

    With the advancement of pharmaceutical development, drug interactions have become increasingly complex. As a result, a computer-based drug interaction search system is required to organize the whole of drug interaction data. To overcome problems faced with the existing systems, we developed a drug interaction search system using a hash table, which offers higher processing speeds and easier maintenance operations compared with relational databases (RDB). In order to compare the performance of our system and MySQL RDB in terms of search speed, drug interaction searches were repeated for all 45 possible combinations of two out of a group of 10 drugs for two cases: 5,604 and 56,040 drug interaction data. As the principal result, our system was able to process the search approximately 19 times faster than the system using the MySQL RDB. Our system also has several other merits such as that drug interaction data can be created in comma-separated value (CSV) format, thereby facilitating data maintenance. Although our system uses the well-known method of a hash table, it is expected to resolve problems common to existing systems and to be an effective system that enables the safe management of drugs.

  18. DISTRIBUTED SYSTEM FOR HUMAN MACHINE INTERACTION IN VIRTUAL ENVIRONMENTS

    Directory of Open Access Journals (Sweden)

    Abraham Obed Chan-Canche

    2017-07-01

    Full Text Available The communication networks built by multiple devices and sensors are becoming more frequent. These device networks allow human-machine interaction development which aims to improve the human performance generating an adaptive environment in response to the information provided by it. The problem of this work is the quick integration of a device network that allows the development of a flexible immersive environment for different uses.

  19. Quantifying Trust, Distrust, and Suspicion in Human-System Interactions

    Science.gov (United States)

    2015-10-26

    communication, psychology , human factors, management, marketing, information technology, and brain/neurology. We first developed a generic model of state...task classification based upon topographic EEG data. Biological Psychology , 1995. 40: p. 239-250. 5. Gevins, A., et al., High-Resolution EEG...Interaction (submitted), 2013. 15. Pouliota, P., et al., Nonlinear hemodynamic responses in human epilepsy : A multimodal analysis with fNIRS-EEG and fMRI

  20. Surface nucleation and growth in the system of interacting particles

    Czech Academy of Sciences Publication Activity Database

    Chvoj, Zdeněk; Chromcová, Zdeňka

    2012-01-01

    Roč. 24, č. 13 (2012), 1-8 ISSN 0953-8984 R&D Projects: GA ČR GPP204/10/P331; GA MŠk ME09048; GA AV ČR IAA100100903 Institutional research plan: CEZ:AV0Z10100521 Keywords : epitaxy * nucleation * island density * graphene * long-range interaction Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 2.355, year: 2012

  1. Socio-Technical Perspective on Interdisciplinary Interactions During the Development of Complex Engineered Systems

    Science.gov (United States)

    McGowan, Anna-Maria R.; Daly, Shanna; Baker, Wayne; Papalambros, panos; Seifert, Colleen

    2013-01-01

    This study investigates interdisciplinary interactions that take place during the research, development, and early conceptual design phases in the design of large-scale complex engineered systems (LaCES) such as aerospace vehicles. These interactions, that take place throughout a large engineering development organization, become the initial conditions of the systems engineering process that ultimately leads to the development of a viable system. This paper summarizes some of the challenges and opportunities regarding social and organizational issues that emerged from a qualitative study using ethnographic and survey data. The analysis reveals several socio-technical couplings between the engineered system and the organization that creates it. Survey respondents noted the importance of interdisciplinary interactions and their benefits to the engineered system as well as substantial challenges in interdisciplinary interactions. Noted benefits included enhanced knowledge and problem mitigation and noted obstacles centered on organizational and human dynamics. Findings suggest that addressing the social challenges may be a critical need in enabling interdisciplinary interactions

  2. The interaction systems generated by the teacher’s didactic imprinting

    Directory of Open Access Journals (Sweden)

    Nadia S. Peralta

    2015-12-01

    Full Text Available The current study aimed to identify and analyze the systems of interaction implemented by teachers in university classes, based on their teaching imprints. It focused on the interactions occurred in scholar natural contexts and the construction of knowledge based on said interaction. A form to observe the different behaviors was designed in order to register the interaction during practical sessions. Six classes and their teachers, from two different epistemic areas (Psychology and Physics, were observed, and the results were analyzed in order to describe the characteristics of the classes and the type of interactions that take place in them. Based on a global qualitative analysis of the classes, three basic types of interaction were detected: collaborative, guided participative and expositive. Beyond the characteristics detected, it is stated that no matter the interaction system, teachers aim to increase the students’ knowledge in all cases.

  3. Mechanism of the Interaction of Cannabinoid System in Central Amygdale with Opioid System

    Directory of Open Access Journals (Sweden)

    S Sarahroodi

    2012-05-01

    Full Text Available

    Background and objectives

    Cannabinoids which are active compounds of marijuana show some pharmacological effects similar to the opioids. There are also functional interactions between both cannabinoid and opioid systems. In this study we investigated the role of cannabinoid receptors in central amygdala and its interaction with opioid system.

                                                                                                                             

    Methods

    In the present study, we investigated the effects of intraperitoneal injection of opioid drugs on response-induced by intra-amygdala (intra-Amyg microinjection of cannabinoid agents in rats, using elevated plus-maze test of anxiety.

     

    Results

    Intraperitoneal injection of morphine (3, 6 and 9 mg/kg increased %OAT and %OAE, but not locomotor activity, showing an anxiolytic response. However, some doses of the opioid receptor antagonist, naloxone reduced %OAT and locomotor activity as well. Intra-Amyg administration of CB1 cannabinoid receptor agonist, ACPA (at the dose of 1.25 and 5 ng/rat increased %OAT and %OAE but not locomotor activity, thus showing an anxiolytic response, which was increased by morphine (6 mg/kg, i.p. without any interaction. Naloxone also reduced ACPA effects.  

    Intra-Amyg administration of CB1 cannabinoid receptor antagonist, AM251 (2.5, 25 and 100 ng/rat did not alter %OAT and %OAE but higher doses of drug (25 and 100 ng/rat reduced locomotor activity. However, the drug in combination of morphine anxiolytic response and with naloxone decreased anxiety.

    Conclusion

    The results may indicate an anxiolytic for CB1 cannabinoid. Our results also showed that opioid

  4. X-ray computed tomography uncovers root-root interactions: quantifying spatial relationships between interacting root systems in three dimensions.

    Science.gov (United States)

    Paya, Alexander M; Silverberg, Jesse L; Padgett, Jennifer; Bauerle, Taryn L

    2015-01-01

    Research in the field of plant biology has recently demonstrated that inter- and intra-specific interactions belowground can dramatically alter root growth. Our aim was to answer questions related to the effect of inter- vs. intra-specific interactions on the growth and utilization of undisturbed space by fine roots within three dimensions (3D) using micro X-ray computed tomography. To achieve this, Populus tremuloides (quaking aspen) and Picea mariana (black spruce) seedlings were planted into containers as either solitary individuals, or inter-/intra-specific pairs, allowed to grow for 2 months, and 3D metrics developed in order to quantify their use of belowground space. In both aspen and spruce, inter-specific root interactions produced a shift in the vertical distribution of the root system volume, and deepened the average position of root tips when compared to intra-specifically growing seedlings. Inter-specific interactions also increased the minimum distance between root tips belonging to the same root system. There was no effect of belowground interactions on the radial distribution of roots, or the directionality of lateral root growth for either species. In conclusion, we found that significant differences were observed more often when comparing controls (solitary individuals) and paired seedlings (inter- or intra-specific), than when comparing inter- and intra-specifically growing seedlings. This would indicate that competition between neighboring seedlings was more responsible for shifting fine root growth in both species than was neighbor identity. However, significant inter- vs. intra-specific differences were observed, which further emphasizes the importance of biological interactions in competition studies.

  5. Transitions of interaction outcomes in a uni-directional consumer-resource system

    Science.gov (United States)

    Wang, Y.; DeAngelis, D.L.

    2011-01-01

    A uni-directional consumer-resource system of two species is analyzed. Our aim is to understand the mechanisms that determine how the interaction outcomes depend on the context of the interaction; that is, on the model parameters. The dynamic behavior of the model is described and, in particular, it is demonstrated that no periodic orbits exist. Then the parameter (factor) space is shown to be divided into four regions, which correspond to the four forms of interaction outcomes; i.e. mutualism, commensalism, parasitism and amensalism. It is shown that the interaction outcomes of the system transition smoothly among these four forms when the parameters of the system are varied continuously. Varying each parameter individually or varying pairs of parameters can also lead to smooth transitions between the interaction outcomes. The analysis leads to both conditions for which each species achieves its maximal density, and situations in which periodic oscillations of the interaction outcomes emerge. ?? 2011 Elsevier Ltd.

  6. Experimental evaluation of human-system interaction on alarm design

    International Nuclear Information System (INIS)

    Huang, F.-H.; Lee, Y.-L.; Hwang, S.-L.; Yenn, T.-C.; Yu, Y.-C.; Hsu, C.-C.; Huang, H.-W.

    2007-01-01

    This study evaluates the practicability of automatic reset alarm system in Fourth Nuclear Power Plant (FNPP) of Taiwan. The features of auto-reset alarm system include dynamic prioritization of all alarm signals and fast system reset. Two experiments were conducted to evaluate the effect of automatic/manual reset on operation time, situational awareness (SA), task load index (TLX), and subjective ratings. All participants, including Experts and Novices, took part in the experiment on the alarm system simulator with Load Rejection procedure. The experimental results imply that the auto-reset alarm system may be applied in an advanced control room under Load Rejection procedure, because all participants' operation time were reduced as well as Novice's SA were raised up. Nevertheless, to ensure operating safety in FNPP, the effects of the auto-reset alarm system in other procedures/special situations still need to be tested in the near future

  7. Multi-Planetary Systems: Observations and Models of Dynamical Interactions

    Science.gov (United States)

    Lissauer, Jack J.

    2018-01-01

    More than 600 multi-planet systems are known. The vast majority of these systems have been discovered by NASA's Kepler spacecraft, but dozens were found using the Doppler technique, the first multi-exoplanet system was identified through pulsar timing, and the most massive system has been found using imaging. More than one-third of the 4000+ planet candidates found by NASA's Kepler spacecraft are associated with target stars that have more than one planet candidate, and the large number of such Kepler "multis" tells us that flat multiplanet systems like our Solar System are common. Virtually all of Kepler candidate multis are stable, as tested by numerical integrations that assume a physically motivated mass-radius relationship. Statistical studies performed on these candidate systems reveal a great deal about the architecture of planetary systems, including the typical spacing of orbits and flatness. The characteristics of several of the most interesting confirmed multi-exoplanet systems will also be discussed.HR 8799's four massive planets orbit tens of AU from their host star and travel on nearly circular orbits. PSR B1257+12 has three much smaller planets orbiting close to a neutron star. Both represent extremes and show that planet formation is a robust process that produces a diversity of outcomes. Although both exomoons and Trojan (triangle Lagrange point) planets have been searched for, neither has yet been found.

  8. An Interactive Computer-Based Circulation System: Design and Development

    Directory of Open Access Journals (Sweden)

    James S. Aagaard

    1972-03-01

    Full Text Available An on-line computer-based circulation control system has been installed at the Northwestern University library. Features of the system include self-service book charge, remote terminal inquiry and update, and automatic production of notices for call-ins and books available. Fine notices are also prepared daily and overdue notices weekly. Important considerations in the design of the system were to minimize costs of operation and to include technical services functions eventually. The system operates on a relatively small computer in a multiprogrammed mode.

  9. Interactive computer graphics and its role in control system design of large space structures

    Science.gov (United States)

    Reddy, A. S. S. R.

    1985-01-01

    This paper attempts to show the relevance of interactive computer graphics in the design of control systems to maintain attitude and shape of large space structures to accomplish the required mission objectives. The typical phases of control system design, starting from the physical model such as modeling the dynamics, modal analysis, and control system design methodology are reviewed and the need of the interactive computer graphics is demonstrated. Typical constituent parts of large space structures such as free-free beams and free-free plates are used to demonstrate the complexity of the control system design and the effectiveness of the interactive computer graphics.

  10. Some preliminary views of plasma interaction: electromagnetic-launch systems

    International Nuclear Information System (INIS)

    Buckingham, A.C.; Hawke, R.S.

    1982-01-01

    This discussion outlines a few areas of fundamental research which appear vital for progress in developing advanced propulsion concepts using dc railgun thrusters. We have placed emphasis on the following: (1) dense plasma and high current density influences on changes in microstructure and properties of conventional rail conductors such as Cu, Al, and W alloys or composites; (2) the influences described in (1) on more advanced high temperature, microstrain resistant, materials such as amorphous tungsten; (3) location, description and temporal evolution of current, magnetic field, and losses during intense plasma-current field interactions with conductors; and (4) composite materials and sequentially sectioned structures for more efficient EM dc launcher configuration

  11. Real-time implementation of an interactive jazz accompaniment system

    Science.gov (United States)

    Deshpande, Nikhil

    Modern computational algorithms and digital signal processing (DSP) are able to combine with human performers without forced or predetermined structure in order to create dynamic and real-time accompaniment systems. With modern computing power and intelligent algorithm layout and design, it is possible to achieve more detailed auditory analysis of live music. Using this information, computer code can follow and predict how a human's musical performance evolves, and use this to react in a musical manner. This project builds a real-time accompaniment system to perform together with live musicians, with a focus on live jazz performance and improvisation. The system utilizes a new polyphonic pitch detector and embeds it in an Ableton Live system - combined with Max for Live - to perform elements of audio analysis, generation, and triggering. The system also relies on tension curves and information rate calculations from the Creative Artificially Intuitive and Reasoning Agent (CAIRA) system to help understand and predict human improvisation. These metrics are vital to the core system and allow for extrapolated audio analysis. The system is able to react dynamically to a human performer, and can successfully accompany the human as an entire rhythm section.

  12. Satellite Navigation Systems: Policy, Commercial and Technical Interaction.

    Science.gov (United States)

    Rycroft, M.

    2003-12-01

    This book adopts a broad perspective on positioning and navigation systems which rely on Earth orbiting satellites for their successful operation. The first of such global systems was the US Global Positioning System (GPS), and the next the Russian GLONASS system. Now studies relating to Europe's future Galileo system are gaining momentum and other nations are planning regional augmentation systems. All such systems are discussed here, particularly relating to political, commercial, legal and technical issues. The opportunities - and also the problems - of having three similar systems in operation simultaneously are examined, and several novel applications are proposed. These range from improved vehicular transport by land, sea and air, to more accurate surveying, more efficient agricultural practices and safer operations in mountainous regions. Everyone who is challenged by these topics will find this volume invaluable. ISU WWW Server; http://www.isunet.edu. Further information on ISU Symposia may also be obtained by e-mail from symposium@isu.isunet.edu Link: http://www.wkap.nl/prod/b/1-4020-1678-6

  13. ORION-the Omega Remote Interactive On-line System

    CERN Document Server

    Russell, R D; Levratt, B; Lipps, H; Sparrman, P

    1974-01-01

    ORION is a system which permits the manipulation of files, records and characters, remote job submittal and retrieval of output files including the direct loading of remote on-line computers. The system uses the computer hardware of the OMEGA project at CERN and is designed to assist researchers in development and debugging of their programs. (10 refs).

  14. ORION - the OMEGA Remote Interactive On-line System

    CERN Document Server

    Russell, R D; Krieger, M

    1973-01-01

    ORION is a system which permits the manipulation of files, records and characters, remote job submittal and retrieval of output files including the direct loading of remote on-line computers. The system uses the computer hardware of the OMEGA project at CERN, and is designed to assist researchers in development and debugging of their programs.

  15. Marketing conception interaction between power system and electric energy loads

    International Nuclear Information System (INIS)

    Bagiev, G.L.; Shneerova, G.V.; Taratin, V.A.; Barykin, E.E.; Zajtsev, O.V.

    1993-01-01

    New concept of functioning fuel-power complex, based on the marketing system is, is presented in brief form. This system includes demand management program, working policy program, active energy-saving policy program and advertisment-service organization program. Methods for realization of demand management and working policy programs are considered

  16. Addressing crop interactions within cropping systems in LCA

    DEFF Research Database (Denmark)

    Goglio, Pietro; Brankatschk, Gerhard; Knudsen, Marie Trydeman

    2018-01-01

    objectives of this discussion article are as follows: (i) to discuss the characteristics of cropping systems which might affect the LCA methodology, (ii) to discuss the advantages and the disadvantages of the current available methods for the life-cycle assessment of cropping systems, and (iii) to offer...... management and emissions, and (3) functional unit issues. The LCA approaches presented are as follows: cropping system, allocation approaches, crop-by-crop approach, and combined approaches. The various approaches are described together with their advantages and disadvantages, applicability...... considers cropping system issues if they are related to multiproduct and nutrient cycling, while the crop-by-crop approach is highly affected by assumptions and considers cropping system issues only if they are related to the analyzed crop. Conclusions Each LCA approach presents advantages and disadvantages...

  17. Extension of lattice cluster theory to strongly interacting, self-assembling polymeric systems.

    Science.gov (United States)

    Freed, Karl F

    2009-02-14

    A new extension of the lattice cluster theory is developed to describe the influence of monomer structure and local correlations on the free energy of strongly interacting and self-assembling polymer systems. This extension combines a systematic high dimension (1/d) and high temperature expansion (that is appropriate for weakly interacting systems) with a direct treatment of strong interactions. The general theory is illustrated for a binary polymer blend whose two components contain "sticky" donor and acceptor groups, respectively. The free energy is determined as an explicit function of the donor-acceptor contact probabilities that depend, in turn, on the local structure and both the strong and weak interactions.

  18. Quantum magnetism in strongly interacting one-dimensional spinor Bose systems

    DEFF Research Database (Denmark)

    Salami Dehkharghani, Amin; Volosniev, A. G.; Lindgren, E. J.

    2015-01-01

    -range inter-species interactions much larger than their intra-species interactions and show that they have novel energetic and magnetic properties. In the strongly interacting regime, these systems have energies that are fractions of the basic harmonic oscillator trap quantum and have spatially separated......Strongly interacting one-dimensional quantum systems often behave in a manner that is distinctly different from their higher-dimensional counterparts. When a particle attempts to move in a one-dimensional environment it will unavoidably have to interact and 'push' other particles in order...... ground states with manifestly ferromagnetic wave functions. Furthermore, we predict excited states that have perfect antiferromagnetic ordering. This holds for both balanced and imbalanced systems, and we show that it is a generic feature as one crosses from few- to many-body systems....

  19. Upper Secondary Students' Understanding of the Basic Physical Interactions in Analogous Atomic and Solar Systems

    Science.gov (United States)

    Taber, Keith S.

    2013-01-01

    Comparing the atom to a "tiny solar system" is a common teaching analogy, and the extent to which learners saw the systems as analogous was investigated. English upper secondary students were asked parallel questions about the physical interactions between the components of a simple atomic system and a simple solar system to investigate…

  20. Interactive water monitoring system accessible by cordless telephone

    Science.gov (United States)

    Volpicelli, Richard; Andeweg, Pierre; Hagar, William G.

    1985-12-01

    A battery-operated, microcomputer-controlled monitoring device linked with a cordless telephone has been developed for remote measurements. This environmental sensor is self-contained and collects and processes data according to the information sent to its on-board computer system. An RCA model 1805 microprocessor forms the basic controller with a program encoded in memory for data acquisition and analysis. Signals from analog sensing devices used to monitor the environment are converted into digital signals and stored in random access memory of the microcomputer. This remote sensing system is linked to the laboratory by means of a cordless telephone whose base unit is connected to regular telephone lines. This offshore sensing system is simply accessed by a phone call originating from a computer terminal in the laboratory. Data acquisition is initiated upon request: Information continues to be processed and stored until the computer is reprogrammed by another phone call request. Information obtained may be recalled by a phone call after the desired environmental measurements are finished or while they are in progress. Data sampling parameters may be reset at any time, including in the middle of a measurement cycle. The range of the system is limited only by existing telephone grid systems and by the transmission characteristics of the cordless phone used as a communications link. This use of a cordless telephone, coupled with the on-board computer system, may be applied to other field studies requiring data transfer between an on-site analytical system and the laboratory.

  1. Identification of Crew-Systems Interactions and Decision Related Trends

    Science.gov (United States)

    Jones, Sharon Monica; Evans, Joni K.; Reveley, Mary S.; Withrow, Colleen A.; Ancel, Ersin; Barr, Lawrence

    2013-01-01

    NASA Vehicle System Safety Technology (VSST) project management uses systems analysis to identify key issues and maintain a portfolio of research leading to potential solutions to its three identified technical challenges. Statistical data and published safety priority lists from academic, industry and other government agencies were reviewed and analyzed by NASA Aviation Safety Program (AvSP) systems analysis personnel to identify issues and future research needs related to one of VSST's technical challenges, Crew Decision Making (CDM). The data examined in the study were obtained from the National Transportation Safety Board (NTSB) Aviation Accident and Incident Data System, Federal Aviation Administration (FAA) Accident/Incident Data System and the NASA Aviation Safety Reporting System (ASRS). In addition, this report contains the results of a review of safety priority lists, information databases and other documented references pertaining to aviation crew systems issues and future research needs. The specific sources examined were: Commercial Aviation Safety Team (CAST) Safety Enhancements Reserved for Future Implementation (SERFIs), Flight Deck Automation Issues (FDAI) and NTSB Most Wanted List and Open Recommendations. Various automation issues taxonomies and priority lists pertaining to human factors, automation and flight design were combined to create a list of automation issues related to CDM.

  2. Feasibility of interactive biking exercise system for telemanagement in elderly.

    Science.gov (United States)

    Finkelstein, Joseph; Jeong, In Cheol

    2013-01-01

    Inexpensive cycling equipment is widely available for home exercise however its use is hampered by lack of tools supporting real-time monitoring of cycling exercise in elderly and coordination with a clinical care team. To address these barriers, we developed a low-cost mobile system aimed at facilitating safe and effective home-based cycling exercise. The system used a miniature wireless 3-axis accelerometer that transmitted the cycling acceleration data to a tablet PC that was integrated with a multi-component disease management system. An exercise dashboard was presented to a patient allowing real-time graphical visualization of exercise progress. The system was programmed to alert patients when exercise intensity exceeded the levels recommended by the patient care providers and to exchange information with a central server. The feasibility of the system was assessed by testing the accuracy of cycling speed monitoring and reliability of alerts generated by the system. Our results demonstrated high validity of the system both for upper and lower extremity exercise monitoring as well as reliable data transmission between home unit and central server.

  3. Sequence Modeling for Analysing Student Interaction with Educational Systems

    DEFF Research Database (Denmark)

    Hansen, Christian; Hansen, Casper; Hjuler, Niklas Oskar Daniel

    2017-01-01

    as exhibiting unproductive student behaviour. Based on our results this student representation is promising, especially for educational systems offering many different learning usages, and offers an alternative to common approaches like modelling student behaviour as a single Markov chain often done......The analysis of log data generated by online educational systems is an important task for improving the systems, and furthering our knowledge of how students learn. This paper uses previously unseen log data from Edulab, the largest provider of digital learning for mathematics in Denmark...

  4. Effects of crystallographic orientation vs. grain interaction on slip systems

    DEFF Research Database (Denmark)

    Winther, Grethe

    . Such investigations reveal both similarities and differences. The present contribution gives an overview of a series of investigations, including transmission electron microscopy as well as three-dimensional x-ray diffraction on polycrystalline aluminium deformed to strains of 5-50%. The data are analysed focusing...... on the set of activated slip systems, more precisely whether the observed differences can be attributed to fluctuations in the relative activities of the same set of systems or whether activation of truly different systems is the origin of the variations between and within grains....

  5. A real-time vision-based hand gesture interaction system for virtual EAST

    Energy Technology Data Exchange (ETDEWEB)

    Wang, K.R., E-mail: wangkr@mail.ustc.edu.cn [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei, Anhui (China); University of Science and Technology of China, Hefei, Anhui (China); Xiao, B.J.; Xia, J.Y. [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei, Anhui (China); University of Science and Technology of China, Hefei, Anhui (China); Li, Dan [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei, Anhui (China); Luo, W.L. [709th Research Institute, Shipbuilding Industry Corporation (China)

    2016-11-15

    Highlights: • Hand gesture interaction is first introduced to EAST model interaction. • We can interact with EAST model by a bared hand and a web camera. • We can interact with EAST model with a distance to screen. • Interaction is free, direct and effective. - Abstract: The virtual Experimental Advanced Superconducting Tokamak device (VEAST) is a very complicated 3D model, to interact with which, the traditional interaction devices are limited and inefficient. However, with the development of human-computer interaction (HCI), the hand gesture interaction has become a much popular choice in recent years. In this paper, we propose a real-time vision-based hand gesture interaction system for VEAST. By using one web camera, we can use our bare hand to interact with VEAST at a certain distance, which proves to be more efficient and direct than mouse. The system is composed of four modules: initialization, hand gesture recognition, interaction control and system settings. The hand gesture recognition method is based on codebook (CB) background modeling and open finger counting. Firstly, we build a background model with CB algorithm. Then, we segment the hand region by detecting skin color regions with “elliptical boundary model” in CbCr flat of YCbCr color space. Open finger which is used as a key feature of gesture can be tracked by an improved curvature-based method. Based on the method, we define nine gestures for interaction control of VEAST. Finally, we design a test to demonstrate effectiveness of our system.

  6. A real-time vision-based hand gesture interaction system for virtual EAST

    International Nuclear Information System (INIS)

    Wang, K.R.; Xiao, B.J.; Xia, J.Y.; Li, Dan; Luo, W.L.

    2016-01-01

    Highlights: • Hand gesture interaction is first introduced to EAST model interaction. • We can interact with EAST model by a bared hand and a web camera. • We can interact with EAST model with a distance to screen. • Interaction is free, direct and effective. - Abstract: The virtual Experimental Advanced Superconducting Tokamak device (VEAST) is a very complicated 3D model, to interact with which, the traditional interaction devices are limited and inefficient. However, with the development of human-computer interaction (HCI), the hand gesture interaction has become a much popular choice in recent years. In this paper, we propose a real-time vision-based hand gesture interaction system for VEAST. By using one web camera, we can use our bare hand to interact with VEAST at a certain distance, which proves to be more efficient and direct than mouse. The system is composed of four modules: initialization, hand gesture recognition, interaction control and system settings. The hand gesture recognition method is based on codebook (CB) background modeling and open finger counting. Firstly, we build a background model with CB algorithm. Then, we segment the hand region by detecting skin color regions with “elliptical boundary model” in CbCr flat of YCbCr color space. Open finger which is used as a key feature of gesture can be tracked by an improved curvature-based method. Based on the method, we define nine gestures for interaction control of VEAST. Finally, we design a test to demonstrate effectiveness of our system.

  7. Fractional exclusion statistics: the method for describing interacting particle systems as ideal gases

    International Nuclear Information System (INIS)

    Anghel, Dragoş-Victor

    2012-01-01

    I show that if the total energy of a system of interacting particles may be written as a sum of quasiparticle energies, then the system of quasiparticles can be viewed, in general, as an ideal gas with fractional exclusion statistics (FES). The general method for calculating the FES parameters is also provided. The interacting particle system cannot be described as an ideal gas of Bose and Fermi quasiparticles except in trivial situations.

  8. Model of interaction in Smart Grid on the basis of multi-agent system

    Science.gov (United States)

    Engel, E. A.; Kovalev, I. V.; Engel, N. E.

    2016-11-01

    This paper presents model of interaction in Smart Grid on the basis of multi-agent system. The use of travelling waves in the multi-agent system describes the behavior of the Smart Grid from the local point, which is being the complement of the conventional approach. The simulation results show that the absorption of the wave in the distributed multi-agent systems is effectively simulated the interaction in Smart Grid.

  9. INTERACTIVITY OF THE MODERN AUTOMATED SYSTEMS OF THE HELP TO THE DRIVER

    OpenAIRE

    Svetlana Alekseevna Vasyugova; Andrey Borisovich Nikolaev

    2017-01-01

    In this article the current technologies in the field of intelligent transportation systems are investigated. The latest systems on control of the safe movement on roads are considered. The analysis of the systems of the help to the driver implemented in cars is carried out. The system concept of the help to the driver of «System help» is offered. Algorithms of work of this system which is based on the principles of interactivity and interaction are investigated. By results of researches expe...

  10. Interactions in multiagent systems fairness, social optimality and individual rationality

    CERN Document Server

    Hao, Jianye

    2016-01-01

    This book mainly aims at solving the problems in both cooperative and competitive multi-agent systems (MASs), exploring aspects such as how agents can effectively learn to achieve the shared optimal solution based on their local information and how they can learn to increase their individual utility by exploiting the weakness of their opponents. The book describes fundamental and advanced techniques of how multi-agent systems can be engineered towards the goal of ensuring fairness, social optimality, and individual rationality; a wide range of further relevant topics are also covered both theoretically and experimentally. The book will be beneficial to researchers in the fields of multi-agent systems, game theory and artificial intelligence in general, as well as practitioners developing practical multi-agent systems.

  11. The ICAP (Interactive Course Assignment Pages Publishing System

    Directory of Open Access Journals (Sweden)

    Kim Griggs

    2008-03-01

    Full Text Available The ICAP publishing system is an open source custom content management system that enables librarians to easily and quickly create and manage library help pages for course assignments (ICAPs, without requiring knowledge of HTML or other web technologies. The system's unique features include an emphasis on collaboration and content reuse and an easy-to-use interface that includes in-line help, simple forms and drag and drop functionality. The system generates dynamic, attractive course assignment pages that blend Web 2.0 features with traditional library resources, and makes the pages easier to find by providing a central web page for the course assignment pages. As of December 2007, the code is available as free, open-source software under the GNU General Public License.

  12. Anthony Pro - Human Automation Interaction in Aerospace Systems, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — This proposed project aims to demonstrate the feasibility and utility of a data mining system designed to facilitate the interpretation of information obtained from...

  13. Augmented Mirror: Interactive Augmented Reality System Based on Kinect

    OpenAIRE

    Vera , Lucía; Gimeno , Jesús; Coma , Inmaculada; Fernández , Marcos

    2011-01-01

    Part 1: Long and Short Papers; International audience; In this paper we present a virtual character controlled by an actor in real time, who talks with an audience through an augmented mirror. The application, which integrates video images, the avatar and other virtual objects within an Augmented Reality system, has been implemented using a mixture of technologies: two kinect systems for motion capture, depth map and real images, a gyroscope to detect head movements, and control algorithms to...

  14. STATLIB, Interactive Statistics Program Library of Tutorial System

    International Nuclear Information System (INIS)

    Anderson, H.E.

    1986-01-01

    1 - Description of program or function: STATLIB is a conversational statistical program library developed in conjunction with a Sandia National Laboratories applied statistics course intended for practicing engineers and scientists. STATLIB is a group of 15 interactive, argument-free, statistical routines. Included are analysis of sensitivity tests; sample statistics for the normal, exponential, hypergeometric, Weibull, and extreme value distributions; three models of multiple regression analysis; x-y data plots; exact probabilities for RxC tables; n sets of m permuted integers in the range 1 to m; simple linear regression and correlation; K different random integers in the range m to n; and Fisher's exact test of independence for a 2 by 2 contingency table. Forty-five other subroutines in the library support the basic 15

  15. Dynamic analysis methods for detecting anomalies in asynchronously interacting systems

    Energy Technology Data Exchange (ETDEWEB)

    Kumar, Akshat; Solis, John Hector; Matschke, Benjamin

    2014-01-01

    Detecting modifications to digital system designs, whether malicious or benign, is problematic due to the complexity of the systems being analyzed. Moreover, static analysis techniques and tools can only be used during the initial design and implementation phases to verify safety and liveness properties. It is computationally intractable to guarantee that any previously verified properties still hold after a system, or even a single component, has been produced by a third-party manufacturer. In this paper we explore new approaches for creating a robust system design by investigating highly-structured computational models that simplify verification and analysis. Our approach avoids the need to fully reconstruct the implemented system by incorporating a small verification component that dynamically detects for deviations from the design specification at run-time. The first approach encodes information extracted from the original system design algebraically into a verification component. During run-time this component randomly queries the implementation for trace information and verifies that no design-level properties have been violated. If any deviation is detected then a pre-specified fail-safe or notification behavior is triggered. Our second approach utilizes a partitioning methodology to view liveness and safety properties as a distributed decision task and the implementation as a proposed protocol that solves this task. Thus the problem of verifying safety and liveness properties is translated to that of verifying that the implementation solves the associated decision task. We develop upon results from distributed systems and algebraic topology to construct a learning mechanism for verifying safety and liveness properties from samples of run-time executions.

  16. Probing Interactions in Complex Molecular Systems through Ordered Assembly

    International Nuclear Information System (INIS)

    De Yoreo, J.J.; Bartelt, M.C.; Orme, C.A.; Villacampa, A.; Weeks, B.L.; Miller, A.E.

    2002-01-01

    Emerging from the machinery of epitaxial science and chemical synthesis, is a growing emphasis on development of self-organized systems of complex molecular species. The nature of self-organization in these systems spans the continuum from simple crystallization of large molecules such as dendrimers and proteins, to assembly into large organized networks of nanometer-scale structures such as quantum dots or nanoparticles. In truth, self-organization in complex molecular systems has always been a central feature of many scientific disciplines including fields as diverse as structural biology, polymer science and geochemistry. But over the past decade, changes in those fields have often been marked by the degree to which researchers are using molecular-scale approaches to understand the hierarchy of structures and processes driven by this ordered assembly. At the same time, physical scientists have begun to use their knowledge of simple atomic and molecular systems to fabricate synthetic self-organized systems. This increasing activity in the field of self-organization is testament to the success of the physical and chemical sciences in building a detailed understanding of crystallization and epitaxy in simple atomic and molecular systems, one that is soundly rooted in thermodynamics and chemical kinetics. One of the fundamental challenges of chemistry and materials science in the coming decades is to develop a similarly well-founded physical understanding of assembly processes in complex molecular systems. Over the past five years, we have successfully used in situ atomic force microscopy (AFM) to investigate the physical controls on single crystal epitaxy from solutions for a wide range of molecular species. More recently, we have combined this method with grazing incidence X-ray diffraction and kinetic Monte Carlo modeling in order to relate morphology to surface atomic structure and processes. The purpose of this proposal was to extend this approach to assemblies

  17. Interaction between lexical and grammatical language systems in the brain

    Science.gov (United States)

    Ardila, Alfredo

    2012-06-01

    This review concentrates on two different language dimensions: lexical/semantic and grammatical. This distinction between a lexical/semantic system and a grammatical system is well known in linguistics, but in cognitive neurosciences it has been obscured by the assumption that there are several forms of language disturbances associated with focal brain damage and hence language includes a diversity of functions (phoneme discrimination, lexical memory, grammar, repetition, language initiation ability, etc.), each one associated with the activity of a specific brain area. The clinical observation of patients with cerebral pathology shows that there are indeed only two different forms of language disturbances (disturbances in the lexical/semantic system and disturbances in the grammatical system); these two language dimensions are supported by different brain areas (temporal and frontal) in the left hemisphere. Furthermore, these two aspects of the language are developed at different ages during child's language acquisition, and they probably appeared at different historical moments during human evolution. Mechanisms of learning are different for both language systems: whereas the lexical/semantic knowledge is based in a declarative memory, grammatical knowledge corresponds to a procedural type of memory. Recognizing these two language dimensions can be crucial in understanding language evolution and human cognition.

  18. Combinations of Methods for Collaborative Evaluation of the Usability of Interactive Software Systems

    Directory of Open Access Journals (Sweden)

    Andrés Solano

    2016-01-01

    Full Text Available Usability is a fundamental quality characteristic for the success of an interactive system. It is a concept that includes a set of metrics and methods in order to obtain easy-to-learn and easy-to-use systems. Usability Evaluation Methods, UEM, are quite diverse; their application depends on variables such as costs, time availability, and human resources. A large number of UEM can be employed to assess interactive software systems, but questions arise when deciding which method and/or combination of methods gives more (relevant information. We propose Collaborative Usability Evaluation Methods, CUEM, following the principles defined by the Collaboration Engineering. This paper analyzes a set of CUEM conducted on different interactive software systems. It proposes combinations of CUEM that provide more complete and comprehensive information about the usability of interactive software systems than those evaluation methods conducted independently.

  19. On the conductivity of a one-dimensional system of interacting fermions in a random potential

    International Nuclear Information System (INIS)

    Apel, W.

    1981-01-01

    A one-dimensional system of interacting fermions in an external potential is studied. The problem was for this purpose transformed to two classical models of statistical mechanics in two dimensions in which occasionally results were found in complementary ranges of the interaction constants of the fermion system. The conductivity appeared as a simple correlation function in both classical models. It was shown that the interaction in a one-dimensional polluted fermion system can cause an isolator-metal transition. (orig./HSI) [de

  20. Dynamic Socio-technical System Design based on Stakeholder Interaction

    Directory of Open Access Journals (Sweden)

    Albert Fleischmann

    2015-07-01

    Full Text Available In order to directly involve stakeholders in socio-technical system design, we argue for streamlining executable process specifications with business process modeling. Due to current agility requirements of organizations, socio-technical system development is considered one of the key activities of members of the organizations. Dynamic process adaptation enable handling the volatility of business operation and IT infrastructure. Subject-oriented process representations are key enablers to dynamic adaptation due to their capability for stakeholders to create directly executable models. In this way stakeholder can be involved in change management pro-actively. Subject-oriented models (i represent all relevant features required for system control and decision making, and (ii are executable on demand. This effectiveness enables organizational change in a creative and efficient way, while establishing innovative design and change management tools. Subject-oriented Business Process Management capabilities are reflected in this realm revealing benefits and potential for further research.

  1. Face detection for interactive tabletop viewscreen system using olfactory display

    Science.gov (United States)

    Sakamoto, Kunio; Kanazawa, Fumihiro

    2009-10-01

    An olfactory display is a device that delivers smells to the nose. It provides us with special effects, for example to emit smell as if you were there or to give a trigger for reminding us of memories. The authors have developed a tabletop display system connected with the olfactory display. For delivering a flavor to user's nose, the system needs to recognition and measure positions of user's face and nose. In this paper, the authors describe an olfactory display which enables to detect the nose position for an effective delivery.

  2. Heuristic models of two-fermion relativistic systems with field-type interaction

    International Nuclear Information System (INIS)

    Duviryak, A

    2002-01-01

    We use the chain of simple heuristic expedients for obtaining perturbative and exactly solvable relativistic spectra for a family of two-fermionic bound systems with Coulomb-like interaction. In the case of electromagnetic interaction the spectrum coincides up to the second order in a coupling constant with that following from the quantum electrodynamics. Discrepancy occurs only for S-states which is the well-known difficulty in the bound-state problem. The confinement interaction is considered too

  3. Magnetic interactions in martensitic Ni-Mn based Heusler systems

    Energy Technology Data Exchange (ETDEWEB)

    Aksoy, Seda

    2010-04-22

    In this work, magnetic, magnetocaloric and structural properties are investigated in Ni-Mn-based martensitic Heusler alloys with the aim to tailor these properties as well as to understand in detail the magnetic interactions in the various crystallographic states of these alloys. We choose Ni{sub 50}Mn{sub 34}In{sub 16} as a prototype which undergoes a martensitic transformation and exhibits field-induced strain and the inverse magnetocaloric effect. Using the structural phase diagram of martensitic Ni-Mn-based Heusler alloys, we substitute gallium and tin for indium to carry these effects systematically closer to room temperature by shifting the martensitic transformation. A magneto-calorimeter is designed and built to measure adiabatically the magnetocaloric effect in these alloys. The temperature dependence of strain under an external magnetic field is studied in Ni{sub 50}Mn{sub 50-x}Z{sub x} (Z: Ga, Sn, In and Sb) and Ni{sub 50}Mn{sub 34}In{sub 16-x}Z{sub x} (Z: Ga and Sn). An argument based on the effect of the applied magnetic field on martensite nucleation is adopted to extract information on the direction of the magnetization easy axis in the martensitic unit cell in Heusler alloys. Parallel to these studies, the structure in the presence of an external field is also studied by powder neutron diffraction. It is demonstrated that martensite nucleation is influenced by cooling the sample under a magnetic field such that the austenite phase is arrested within the martensitic state. The magnetic interactions in Ni{sub 50}Mn{sub 37}Sn{sub 13} and Ni{sub 50}Mn{sub 40}Sb{sub 10} are characterized by using neutron polarization analysis. Below the martensitic transformation temperature, M{sub s}, an antiferromagnetically correlated state is found. Ferromagnetic resonance experiments are carried out on Ni{sub 50}Mn{sub 37}Sn{sub 13} and Ni{sub 50}Mn{sub 34}In{sub 16} to gain more detailed information on the nature of the magnetic interactions. The experimental

  4. Auditory display as feedback for a novel eye-tracking system for sterile operating room interaction.

    Science.gov (United States)

    Black, David; Unger, Michael; Fischer, Nele; Kikinis, Ron; Hahn, Horst; Neumuth, Thomas; Glaser, Bernhard

    2018-01-01

    The growing number of technical systems in the operating room has increased attention on developing touchless interaction methods for sterile conditions. However, touchless interaction paradigms lack the tactile feedback found in common input devices such as mice and keyboards. We propose a novel touchless eye-tracking interaction system with auditory display as a feedback method for completing typical operating room tasks. Auditory display provides feedback concerning the selected input into the eye-tracking system as well as a confirmation of the system response. An eye-tracking system with a novel auditory display using both earcons and parameter-mapping sonification was developed to allow touchless interaction for six typical scrub nurse tasks. An evaluation with novice participants compared auditory display with visual display with respect to reaction time and a series of subjective measures. When using auditory display to substitute for the lost tactile feedback during eye-tracking interaction, participants exhibit reduced reaction time compared to using visual-only display. In addition, the auditory feedback led to lower subjective workload and higher usefulness and system acceptance ratings. Due to the absence of tactile feedback for eye-tracking and other touchless interaction methods, auditory display is shown to be a useful and necessary addition to new interaction concepts for the sterile operating room, reducing reaction times while improving subjective measures, including usefulness, user satisfaction, and cognitive workload.

  5. Aluminum–Nitrogen Interactions in the Soil–Plant System

    Directory of Open Access Journals (Sweden)

    Xue Q. Zhao

    2018-06-01

    Full Text Available Aluminum (Al is the most abundant metal in the Earth’s crust and is not an essential element for plant growth. In contrast, nitrogen (N is the most important mineral element for plant growth, but this non-metal is often present at low levels in soils, and plants are often N deficient. Aluminum toxicity is dominant in acid soils, and so plants growing in acid soils have to overcome both Al toxicity and N limitation. Because of low N-use efficiency, large amounts of N fertilizers are applied to crop fields to achieve high yields, leading to soil acidification and potential Al toxicity. Aluminum lowers plant N uptake and N-use efficiency because Al inhibits root growth. Although numerous studies have investigated the interactions between Al and N, a complete review of these studies was lacking. This review describes: (1 the link between plant Al tolerance and ammonium/nitrate (NH4+/NO3- preference; (2 the effects of NH4+/NO3- and pH on Al toxicity; (3 the effects of Al on soil N transformations; and (4 the effects of Al on NH4+/NO3- uptake and assimilation by plants. Acid soils are characterized chemically by a relatively high ratio of NH4+ to NO3- and high concentrations of toxic Al. Aluminum-tolerant plants generally prefer NH4+ as an N source, while Al-sensitive plants prefer NO3-. Compared with NO3-, NH4+ increases the solubilization of toxic Al into soil solutions, but NH4+ generally alleviates Al phytotoxicity under solution culture because the protons from NH4+ compete with Al3+ for adsorption sites on the root surface. Plant NO3- uptake and nitrate reductase activity are both inhibited by Al, while plant NH4+ uptake is inhibited to a smaller degree than NO3-. Together, the results of numerous studies indicate that there is a synergistic interaction between plant Al tolerance and NH4+ nutrition. This has important implications for the adaptation of plants to acid soils that are dominated chemically by toxic Al as well as NH4+. Finally, we

  6. A quantum spin system with random interactions I

    Indian Academy of Sciences (India)

    . In order to study the dynamics of a quantum spin glass we model it as a .... Next we construct a family of strongly continuous one-parameter groups of c-auto- morphisms which determine the evolution of the spin system. To this end, we have ...

  7. Graph-Based Interactive Bibliographic Information Retrieval Systems

    Science.gov (United States)

    Zhu, Yongjun

    2017-01-01

    In the big data era, we have witnessed the explosion of scholarly literature. This explosion has imposed challenges to the retrieval of bibliographic information. Retrieval of intended bibliographic information has become challenging due to the overwhelming search results returned by bibliographic information retrieval systems for given input…

  8. Interacting with Multi-Robot Systems Using BML

    Science.gov (United States)

    2013-06-01

    presented to the operator. 1. Introduction There are many operations in which a multi-robot system (MRS) can be deployed to support the human forces...within the MRS easily. © Fraunhofer FKIE Communication Architecture ~ ~ Fraunhofer FKIE © Fraunhofer FKIE Battle Mangement Language BML...Fraunhofer FKIE Battle Mangement Language Orders Orders move patrol observe distribute guard recce imagery intelligence gathering

  9. Interactions of the histamine and hypocretin systems in CNS disorders.

    Science.gov (United States)

    Shan, Ling; Dauvilliers, Yves; Siegel, Jerome M

    2015-07-01

    Histamine and hypocretin neurons are localized to the hypothalamus, a brain area critical to autonomic function and sleep. Narcolepsy type 1, also known as narcolepsy with cataplexy, is a neurological disorder characterized by excessive daytime sleepiness, impaired night-time sleep, cataplexy, sleep paralysis and short latency to rapid eye movement (REM) sleep after sleep onset. In narcolepsy, 90% of hypocretin neurons are lost; in addition, two groups reported in 2014 that the number of histamine neurons is increased by 64% or more in human patients with narcolepsy, suggesting involvement of histamine in the aetiology of this disorder. Here, we review the role of the histamine and hypocretin systems in sleep-wake modulation. Furthermore, we summarize the neuropathological changes to these two systems in narcolepsy and discuss the possibility that narcolepsy-associated histamine abnormalities could mediate or result from the same processes that cause the hypocretin cell loss. We also review the changes in the hypocretin and histamine systems, and the associated sleep disruptions, in Parkinson disease, Alzheimer disease, Huntington disease and Tourette syndrome. Finally, we discuss novel therapeutic approaches for manipulation of the histamine system.

  10. State level operations and interaction with facility level systems

    International Nuclear Information System (INIS)

    Bellinger, J.

    1989-01-01

    The role of the State System of Accounting for and Control of Nuclear Materials at the State level, particularly the role of the National Authority, in ensuring that both national and international safeguards objectives are met is discussed. The legislative basis for the National Authority is examined. The activities of Australia's National Authority - the Australian Safeguards Office - are described

  11. Duality and hidden symmetries in interacting particle systems

    NARCIS (Netherlands)

    Giardinà, C.; Kurchan, J.; Redig, F.H.J.; Vafayi, K.

    2009-01-01

    In the context of Markov processes, both in discrete and continuous setting, we show a general relation between duality functions and symmetries of the generator. If the generator can be written in the form of a Hamiltonian of a quantum spin system, then the "hidden" symmetries are easily derived.

  12. Organization of functional interaction of corporate information systems

    Science.gov (United States)

    Safronov, V. V.; Barabanov, V. F.; Podvalniy, S. L.; Nuzhnyy, A. M.

    2018-03-01

    In this article the methods of specialized software systems integration are analyzed and the concept of seamless integration of production decisions is offered. In view of this concept developed structural and functional schemes of the specialized software are shown. The proposed schemes and models are improved for a machine-building enterprise.

  13. Simulation of interaction between wind farm and power system

    DEFF Research Database (Denmark)

    Sørensen, Poul Ejnar; Hansen, Anca Daniela; Janosi, L.

    2002-01-01

    A dynamic model of the wind farm Hagesholm has been implemented in the dedicated power system simulation program DIgSILENT. The wind farm con- sists of six 2MW NM2000/72 wind turbines from NEG-Micon. The model has been verified using simultaneous powerquality measurements on the 10 kV terminals...

  14. Interactions between co-expressed Arabidopsis sucrose transporters in the split-ubiquitin system

    Directory of Open Access Journals (Sweden)

    Lalonde Sylvie

    2003-03-01

    Full Text Available Abstract Background The Arabidopsis genome contains nine sucrose transporter paralogs falling into three clades: SUT1-like, SUT2 and SUT4. The carriers differ in their kinetic properties. Many transport proteins are known to exist as oligomers. The yeast-based split ubiquitin system can be used to analyze the ability of membrane proteins to interact. Results Promoter-GUS fusions were used to analyze the cellular expression of the three transporter genes in transgenic Arabidopsis plants. All three fusion genes are co-expressed in companion cells. Protein-protein interactions between Arabidopsis sucrose transporters were tested using the split ubiquitin system. Three paralogous sucrose transporters are capable of interacting as either homo- or heteromers. The interactions are specific, since a potassium channel and a glucose transporter did not show interaction with sucrose transporters. Also the biosynthetic and metabolizing enzymes, sucrose phosphate phosphatase and sucrose synthase, which were found to be at least in part bound to the plasma membrane, did not specifically interact with sucrose transporters. Conclusions The split-ubiquitin system provides a powerful tool to detect potential interactions between plant membrane proteins by heterologous expression in yeast, and can be used to screen for interactions with membrane proteins as baits. Like other membrane proteins, the Arabidopsis sucrose transporters are able to form oligomers. The biochemical approaches are required to confirm the in planta interaction.

  15. Reducing drug–herb interaction risk with a computerized reminder system

    Science.gov (United States)

    Lin, Sheng-Shing; Tsai, Chiu-Lin; Tu, Ching-Yeh; Hsieh, Ching-Liang

    2015-01-01

    Background Traditional Chinese medicine (TCM) and Western medicine are both popular in Taiwan. Approximately 14.1% of Taiwanese residents use Western drugs and Chinese herbs concurrently; therefore, drug–herb interaction is critical to patient safety. This paper presents a new procedure for reducing the risk of drug interactions. Methods Hospital computer systems are modified to ensure that drug–herb interactions are automatically detected when a TCM practitioner is writing a prescription. A pop-up reminder appears, warning of interactions, and the practitioner may adjust doses, delete herbs, or leave the prescription unchanged. A pharmacist will receive interaction information through the system and provide health education to the patient. Results During the 2011–2013 study period, 256 patients received 891 herbal prescriptions with potential drug–herb interactions. Three of the 50 patients who concurrently used ginseng and antidiabetic drugs manifested hypoglycemia (fasting blood sugar level ≤70 mg/dL). Conclusion Drug–herb interactions can cause adverse reactions. A computerized reminder system can enable TCM practitioners to reduce the risk of drug–herb interactions. In addition, health education for patients is crucial in avoiding adverse reaction by the interactions. PMID:25733840

  16. Neurobiological Interactions Between Stress and the Endocannabinoid System.

    Science.gov (United States)

    Morena, Maria; Patel, Sachin; Bains, Jaideep S; Hill, Matthew N

    2016-01-01

    Stress affects a constellation of physiological systems in the body and evokes a rapid shift in many neurobehavioral processes. A growing body of work indicates that the endocannabinoid (eCB) system is an integral regulator of the stress response. In the current review, we discuss the evidence to date that demonstrates stress-induced regulation of eCB signaling and the consequential role changes in eCB signaling have with respect to many of the effects of stress. Across a wide array of stress paradigms, studies have generally shown that stress evokes bidirectional changes in the two eCB molecules, anandamide (AEA) and 2-arachidonoyl glycerol (2-AG), with stress exposure reducing AEA levels and increasing 2-AG levels. Additionally, in almost every brain region examined, exposure to chronic stress reliably causes a downregulation or loss of cannabinoid type 1 (CB1) receptors. With respect to the functional role of changes in eCB signaling during stress, studies have demonstrated that the decline in AEA appears to contribute to the manifestation of the stress response, including activation of the hypothalamic-pituitary-adrenal (HPA) axis and increases in anxiety behavior, while the increased 2-AG signaling contributes to termination and adaptation of the HPA axis, as well as potentially contributing to changes in pain perception, memory and synaptic plasticity. More so, translational studies have shown that eCB signaling in humans regulates many of the same domains and appears to be a critical component of stress regulation, and impairments in this system may be involved in the vulnerability to stress-related psychiatric conditions, such as depression and posttraumatic stress disorder. Collectively, these data create a compelling argument that eCB signaling is an important regulatory system in the brain that largely functions to buffer against many of the effects of stress and that dynamic changes in this system contribute to different aspects of the stress response.

  17. Correcting binding parameters for interacting ligand-lattice systems

    Science.gov (United States)

    Hervy, Jordan; Bicout, Dominique J.

    2017-07-01

    Binding of ligands to macromolecules is central to many functional and regulatory biological processes. Key parameters characterizing ligand-macromolecule interactions are the stoichiometry, inducing the number of ligands per macromolecule binding site, and the dissociation constant, quantifying the ligand-binding site affinity. Both these parameters can be obtained from analyses of classical saturation experiments using the standard binding equation that offers the great advantage of mathematical simplicity but becomes an approximation for situations of interest when a ligand binds and covers more than one single binding site on the macromolecule. Using the framework of car-parking problem with latticelike macromolecules where each ligand can cover simultaneously several consecutive binding sites, we showed that employing the standard analysis leads to underestimation of binding parameters, i.e., ligands appear larger than they actually are and their affinity is also greater than it is. Therefore, we have derived expressions allowing to determine the ligand size and true binding parameters (stoichiometry and dissociation constant) as a function of apparent binding parameters retrieved from standard saturation experiments.

  18. A Tabletop Board Game Interface for Multi-User Interaction with a Storytelling System

    NARCIS (Netherlands)

    Alofs, T.; Theune, Mariet; Swartjes, I.M.T.; Camurri, A.; Costa, C.

    2011-01-01

    The Interactive Storyteller is an interactive storytelling system with a multi-user tabletop interface. Our goal was to design a generic framework combining emergent narrative, where stories emerge from the actions of autonomous intelligent agents, with the social aspects of traditional board games.

  19. Development of a Mixed Scanning Interactive System for Decision Support.

    Science.gov (United States)

    1984-07-01

    employment and unemployment effects on certain con- tractors, granting of subcontracts of a system for the sake of keeping a base of companies...standardization of jobs, and stratification of employment levels [16]. In this view, everything is functional and tuned such that all resource inputs are...assumed to be given for every alterna- We observe that if u, is described by linear inequaities tive nair (a’, a). We remark that if A’(a’. a) 9 A(a

  20. Usable, Real-Time, Interactive Spoken Language Systems

    Science.gov (United States)

    1994-09-01

    Similarly, we included derivations (mostly plurals and possessives) of many open-class words in the domnain. We also added about 400 concatenated word...UueraiCe’l~ usinig a system of’ ’realization 1111C, %%. hiCh map) thle gr-aimmlatcal relation anl argumlent bears to the head onto thle semantic relatio ...syntactic categories as well. Representations of this form contain significantly more internal structure than specialized sublanguage models. This can be

  1. Properties of the hadronic system produced in antineutrino proton interactions

    International Nuclear Information System (INIS)

    Musgrave, B.

    1979-01-01

    The separation of the hadronic system produced in anti νp charged-current reactions into the current and target fragmentation components is discussed. The current fragments show properties in good qualitative agreement with the expectations of the naive quark-parton model. In particular, there is no evidence for either a Q 2 - or X/sub BJ/-dependence of the fragmentation functions. 7 references

  2. Interactive Editing and Cataloging Interfaces for Modern Digital Library Systems

    CERN Document Server

    Raae, L C; Helstrup, H

    2009-01-01

    The next-generation High Energy Physics information system, INSPIRE, is being built by combining the content from the successful SPIRES database of bibliographic information with the CDS Invenio software being developed at CERN, an open-source platform for large digital library systems. The project is a collaboration between four major particle physics laboratories in Europe and the U.S. New tools are being developed to enable the global cooperation between catalogers at these labs. The BibEdit module will provide a central interface for the editing, enrichment, correction and verification of a record on its way into the system, by processing and presenting data from several supporting modules to the cataloger. The objective is to minimize the time and actions needed by the cataloger to process the record. To create a fast and powerful web application we make use of modern AJAX technology to create a dynamic and responsive user interface, where server communication happens in the background without delaying t...

  3. Development of Interactive Monitoring System for Neutron Scattering Instrument

    Energy Technology Data Exchange (ETDEWEB)

    So, Ji Yong [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    Neutron scattering instruments in HANARO research reactor have been contributed to various fields of basic science and material engineering. These instruments are open to publics and researchers can apply beam-time and do experiments with instrument scientists. In most cases, these instruments run for several weeks without stopping, and therefore instrument scientist wants to see the instrument status and receive information if the instruments have some problem. This is important for the safety. However, it is very hard to get instrument information outside of instruments. Access from external site is strongly forbidden in the institute due to the network safety, I developed another way to send instrument status information using commercial short messaging service(SMS). In this presentation, detailed features of this system will be shown. As a prototype, this system is being developed for the single instrument: Disk-chopper time-of-flight instruments (DC-TOF). I have successfully developed instruments and operate for several years. This information messaging system can be used for other neutron scattering instruments.

  4. The Design of an Interactive Data Retrieval System for Casual Users.

    Science.gov (United States)

    Radhakrishnan, T.; And Others

    1982-01-01

    Describes an interactive data retrieval system which was designed and implemented for casual users and which incorporates a user-friendly interface, aids to train beginners in use of the system, versatility in output, and error recovery protocols. A 14-item reference list and two figures illustrating system operation and output are included. (JL)

  5. Study of Personalized Network Tutoring System Based on Emotional-cognitive Interaction

    Science.gov (United States)

    Qi, Manfei; Ma, Ding; Wang, Wansen

    Aiming at emotion deficiency in present Network tutoring system, a lot of negative effects is analyzed and corresponding countermeasures are proposed. The model of Personalized Network tutoring system based on Emotional-cognitive interaction is constructed in the paper. The key techniques of realizing the system such as constructing emotional model and adjusting teaching strategies are also introduced.

  6. 76 FR 39763 - Special Conditions: Boeing Model 787-8 Airplane; Interaction of Systems and Structures...

    Science.gov (United States)

    2011-07-07

    ... Conditions No. 25-354A-SC] Special Conditions: Boeing Model 787-8 Airplane; Interaction of Systems and..., electronic flight control system control surface awareness, HIRF protection, limit engine torque loads for... standards. A special condition is needed to require consideration of the effects of systems on the...

  7. Interaction between national and international information systems: The case of AGRIS and CARIS

    International Nuclear Information System (INIS)

    Samaha, E.K.

    1990-05-01

    The international cooperative information system as exemplified by IAEA's INIS and FAO's AGRIS and CARIS is based on national partnership. A unique type of interaction exists between this system and national systems. This paper outlines this relationship with examples drawn from AGRIS and CARIS, and looks at future prospects in the 1990s

  8. K-Anonymity Based Privacy Risk Budgeting System for Interactive Record Linkage

    Directory of Open Access Journals (Sweden)

    Hye-Chung Kum

    2017-04-01

    The k-anonymity based privacy risk budgeting system provides a mechanism where we can concretely reason about the tradeoff between the privacy risks due to information disclosed, accuracy gained, and biases reduced during interactive record linkage.

  9. Energy distribution system operator in interaction with social actors : Three cases

    NARCIS (Netherlands)

    Steenhuisen, B.M.; Veeneman, W.W.; Van Doorn, L.; Van Breen, H.

    2012-01-01

    A publicly owned Dutch energy distribution system operator (DSO) interacts during local infrastructure projects with its direct stakeholders to maximize utility in the public interest. These projects are about replacing, relocating, removing or reconstructing parts of the gas and electricity

  10. A direct probe of dark energy interactions with a solar System laboratory

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose a mission concept for direct detection of dark energy interactions with normal matter in a Solar System laboratory. Dark energy is the leading proposal to...

  11. An integrated model for interaction of electromagnetic fields with biological systems

    International Nuclear Information System (INIS)

    Apollonio, F.; Liberti, M.; Cavagnaro, M.; D'Inzeo, G.; Tarricone, L.

    1999-01-01

    In this work is described a methodology for evaluation of interaction of high frequency electromagnetic field. Biological systems via connection of many macroscopic models. In particular the analysis of neuronal membrane exposed to electromagnetic fields [it

  12. Hospital's activity-based financing system and manager-physician [corrected] interaction.

    Science.gov (United States)

    Crainich, David; Leleu, Hervé; Mauleon, Ana

    2011-10-01

    This paper examines the consequences of the introduction of an activity-based reimbursement system on the behavior of physicians and hospital's managers. We consider a private for-profit sector where both hospitals and physicians are initially paid on a fee-for-service basis. We show that the benefit of the introduction of an activity-based system depends on the type of interaction between managers and physicians (simultaneous or sequential decision-making games). It is shown that, under the activity-based system, a sequential interaction with physician leader could be beneficial for both agents in the private sector. We further model an endogenous timing game à la Hamilton and Slutsky (Games Econ Behav 2: 29-46, 1990) in which the type of interaction is determined endogenously. We show that, under the activity-based system, the sequential interaction with physician leader is the unique subgame perfect equilibrium.

  13. Reduction of Flight Control System/Structural Mode Interaction, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — A novel approach is proposed for reducing the degree of interaction of a high gain flight control system with the airframe structural vibration modes, representing a...

  14. Interactive graphical system for small-angle scattering analysis of polydisperse systems

    International Nuclear Information System (INIS)

    Konarev, P V; Volkov, V V; Svergun, D I

    2016-01-01

    A program suite for one-dimensional small-angle scattering analysis of polydisperse systems and multiple data sets is presented. The main program, POLYSAS , has a menu-driven graphical user interface calling computational modules from ATSAS package to perform data treatment and analysis. The graphical menu interface allows one to process multiple (time, concentration or temperature-dependent) data sets and interactively change the parameters for the data modelling using sliders. The graphical representation of the data is done via the Winteracter-based program SASPLOT . The package is designed for the analysis of polydisperse systems and mixtures, and permits one to obtain size distributions and evaluate the volume fractions of the components using linear and non-linear fitting algorithms as well as model-independent singular value decomposition. The use of the POLYSAS package is illustrated by the recent examples of its application to study concentration-dependent oligomeric states of proteins and time kinetics of polymer micelles for anticancer drug delivery. (paper)

  15. Dewetting and Hydrophobic Interaction in Physical and Biological Systems

    Science.gov (United States)

    Berne, Bruce J.; Weeks, John D.; Zhou, Ruhong

    2013-01-01

    Hydrophobicity manifests itself differently on large and small length scales. This review focuses on large length scale hydrophobicity, particularly on dewetting at single hydrophobic surfaces and drying in regions bounded on two or more sides by hydrophobic surfaces. We review applicable theories, simulations and experiments pertaining to large scale hydrophobicity in physical and biomoleclar systems and clarify some of the critical issues pertaining to this subject. Given space constraints, we could not review all of the significant and interesting work in this very active field. PMID:18928403

  16. Pilot interaction with automated airborne decision making systems

    Science.gov (United States)

    Hammer, John M.; Wan, C. Yoon; Vasandani, Vijay

    1987-01-01

    The current research is focused on detection of human error and protection from its consequences. A program for monitoring pilot error by comparing pilot actions to a script was described. It dealt primarily with routine errors (slips) that occurred during checklist activity. The model to which operator actions were compared was a script. Current research is an extension along these two dimensions. The ORS fault detection aid uses a sophisticated device model rather than a script. The newer initiative, the model-based and constraint-based warning system, uses an even more sophisticated device model and is to prevent all types of error, not just slips or bad decision.

  17. Corrosion Degradation of Coated Aluminum Alloy Systems through Galvanic Interactions

    Science.gov (United States)

    2017-07-19

    REPORT DATE (DD-MM-YYYY) 2. REPORT TYPE 3. DATES COVERED (From - To) 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM...19b. TELEPHONE NUMBER (Include area code) Corrosion  Degradation  of  Coated  Aluminum  Alloy  Systems  through  Galvanic...their  low  density  and  relatively  high  strength.   While  exhibiting  significant  general   corrosion  resistance,  these

  18. Computer-aided system for interactive psychomotor testing

    Science.gov (United States)

    Selivanova, Karina G.; Ignashchuk, Olena V.; Koval, Leonid G.; Kilivnik, Volodymyr S.; Zlepko, Alexandra S.; Sawicki, Daniel; Kalizhanova, Aliya; Zhanpeisova, Aizhan; Smailova, Saule

    2017-08-01

    Nowadays research of psychomotor actions has taken a special place in education, sports, medicine, psychology etc. Development of computer system for psychomotor testing could help solve many operational problems in psychoneurology and psychophysiology and also determine the individual characteristics of fine motor skills. This is particularly relevant issue when it comes to children, students, athletes for definition of personal and professional features. The article presents the dynamics of a developing psychomotor skills and application in the training process of means. The results of testing indicated their significant impact on psychomotor skills development.

  19. PHIDIAS: a pathogen-host interaction data integration and analysis system

    OpenAIRE

    Xiang, Zuoshuang; Tian, Yuying; He, Yongqun

    2007-01-01

    The Pathogen-Host Interaction Data Integration and Analysis System (PHIDIAS) is a web-based database system that serves as a centralized source to search, compare, and analyze integrated genome sequences, conserved domains, and gene expression data related to pathogen-host interactions (PHIs) for pathogen species designated as high priority agents for public health and biological security. In addition, PHIDIAS allows submission, search and analysis of PHI genes and molecular networks curated ...

  20. Global Positioning Systems (GPS) Technology to Study Vector-Pathogen-Host Interactions

    Science.gov (United States)

    2016-12-01

    Award Number: W81XWH-11-2-0175 TITLE: Global Positioning Systems (GPS) Technology to Study Vector-Pathogen-Host Interactions PRINCIPAL...Positioning Systems (GPS) Technology to Study Vector-Pathogen-Host Interactions 5b. GRANT NUMBER W81XWH-11-2-0175 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S...genetic diversity in the population, in hospitalized children with severe dengue illness and cluster investigation of their neighborhoods, and by using

  1. Interactive tele-radiological segmentation systems for treatment and diagnosis.

    Science.gov (United States)

    Zimeras, S; Gortzis, L G

    2012-01-01

    Telehealth is the exchange of health information and the provision of health care services through electronic information and communications technology, where participants are separated by geographic, time, social and cultural barriers. The shift of telemedicine from desktop platforms to wireless and mobile technologies is likely to have a significant impact on healthcare in the future. It is therefore crucial to develop a general information exchange e-medical system to enables its users to perform online and offline medical consultations through diagnosis. During the medical diagnosis, image analysis techniques combined with doctor's opinions could be useful for final medical decisions. Quantitative analysis of digital images requires detection and segmentation of the borders of the object of interest. In medical images, segmentation has traditionally been done by human experts. Even with the aid of image processing software (computer-assisted segmentation tools), manual segmentation of 2D and 3D CT images is tedious, time-consuming, and thus impractical, especially in cases where a large number of objects must be specified. Substantial computational and storage requirements become especially acute when object orientation and scale have to be considered. Therefore automated or semi-automated segmentation techniques are essential if these software applications are ever to gain widespread clinical use. The main purpose of this work is to analyze segmentation techniques for the definition of anatomical structures under telemedical systems.

  2. Interactive Tele-Radiological Segmentation Systems for Treatment and Diagnosis

    Directory of Open Access Journals (Sweden)

    S. Zimeras

    2012-01-01

    Full Text Available Telehealth is the exchange of health information and the provision of health care services through electronic information and communications technology, where participants are separated by geographic, time, social and cultural barriers. The shift of telemedicine from desktop platforms to wireless and mobile technologies is likely to have a significant impact on healthcare in the future. It is therefore crucial to develop a general information exchange e-medical system to enables its users to perform online and offline medical consultations through diagnosis. During the medical diagnosis, image analysis techniques combined with doctor’s opinions could be useful for final medical decisions. Quantitative analysis of digital images requires detection and segmentation of the borders of the object of interest. In medical images, segmentation has traditionally been done by human experts. Even with the aid of image processing software (computer-assisted segmentation tools, manual segmentation of 2D and 3D CT images is tedious, time-consuming, and thus impractical, especially in cases where a large number of objects must be specified. Substantial computational and storage requirements become especially acute when object orientation and scale have to be considered. Therefore automated or semi-automated segmentation techniques are essential if these software applications are ever to gain widespread clinical use. The main purpose of this work is to analyze segmentation techniques for the definition of anatomical structures under telemedical systems.

  3. An interactive roof bolting selection and performance system

    Energy Technology Data Exchange (ETDEWEB)

    Agioutantis, Z.; Stiakakis, C.; Stiakakis, N. [Technical Univ. of Crete, Chania (Greece); Karmis, M. [Virginia Polytechnic Inst. and State Univ. (United States)

    2001-07-01

    In the last decades, bolting has become one of the most dominant support methods in underground construction, including both mining as well as civil engineering applications. A variety of bolt types has been developed in order to meet the support needs of different geological and geotechnical settings. The selection of the appropriate bolt type, as well as the troubleshooting procedures in case of failure or suspected failure, are often complex and require extensive experience. To facilitate bolt type selection as well as troubleshooting, various tools have been presented in the form of nomograms, computer programs or trouble shooting guides. The approach described in this paper incorporates information and data developed by laboratory and field investigations and has led to the development of a dynamic knowledge base system that can aid in the selection of appropriate bolting systems and, also, help troubleshoot existing installations. Additionally, the user can enhance the functionality of the existing database with site-specific information and geological behavior as experienced by field personnel. The package is developed as a Windows trademark based application, where data is stored in Microsoft Access trademark database. (orig.)

  4. Entropy balance in pure interactions of open quantum systems

    International Nuclear Information System (INIS)

    Urigu, R.

    1989-01-01

    Processes are considered in which a statistical ensemble w of quantum systems is split into ensembles, or channels (w i ), conditional to the occurrence, with respective probabilities (p i w ), of associated macroscopic effects. These processes are described here by a family of operations T i : w → p i w w iT , which remarkably generalize the usual state reductions of the nondestructive measurements. In a previous work it was proved that the microscopic entropy of the given open system decreases or at most remains constant if all the T i are pure operations, i.e., they transform pure states into pure states; it is proved here that the increase in entropy of the external world, computed as S Tm (w) = - Σ i p i w lg p i w , is sufficient to compensate for such an entropy decrease whenever the T i are all pure operations of the first kind, whereas whenever some T i is pure of the second kind (or nonpure, too), the total entropy, computed as above, may decrease

  5. Synchronization of multi-agent systems with metric-topological interactions.

    Science.gov (United States)

    Wang, Lin; Chen, Guanrong

    2016-09-01

    A hybrid multi-agent systems model integrating the advantages of both metric interaction and topological interaction rules, called the metric-topological model, is developed. This model describes planar motions of mobile agents, where each agent can interact with all the agents within a circle of a constant radius, and can furthermore interact with some distant agents to reach a pre-assigned number of neighbors, if needed. Some sufficient conditions imposed only on system parameters and agent initial states are presented, which ensure achieving synchronization of the whole group of agents. It reveals the intrinsic relationships among the interaction range, the speed, the initial heading, and the density of the group. Moreover, robustness against variations of interaction range, density, and speed are investigated by comparing the motion patterns and performances of the hybrid metric-topological interaction model with the conventional metric-only and topological-only interaction models. Practically in all cases, the hybrid metric-topological interaction model has the best performance in the sense of achieving highest frequency of synchronization, fastest convergent rate, and smallest heading difference.

  6. An interactive game-based shoulder wheel system for rehabilitation

    Directory of Open Access Journals (Sweden)

    Chou LW

    2012-11-01

    Full Text Available Chun-Ming Chang,1,* Yen-Ching Chang,2,3 Hsiao-Yun Chang,4 Li-Wei Chou5,6,* 1Department of Applied Informatics and Multimedia, Asia University, Taichung, Taiwan; 2Department of Medical Informatics, Chung Shan Medical University, Taichung, Taiwan; 3Department of Medical Imaging, Chung Shan Medical University Hospital, Taichung, Taiwan; 4Department of Biotechnology, Asia University, Taichung, Taiwan; 5Department of Physical Medicine and Rehabilitation, China Medical University Hospital, Taichung, Taiwan; 6School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan*These authors contributed equally to this workBackground: Increases in the aging population and in the number of accidents have resulted in more people suffering from physical impairments or disabilities. Rehabilitation therapy thus attracts greater attention as a means of helping patients recover and return to a normal life. With the extremely long and tedious nature of traditional rehabilitation, patients are reluctant to continue the entire process, thus the expected effects of the therapy cannot be obtained. Games are well known to help patients improve their concentration and shift their attention away from the discomfort of their injuries during rehabilitation. Thus, incorporating game technology into a rehabilitation program may be a promising approach.Methods: In this study, a gaming system used for shoulder rehabilitation was developed. The mechanical parts and electric circuits were integrated to mimic the functionalities of a shoulder wheel. Several games were also designed to suit the rehabilitation needs of the patients based on the age and gender differences among the individual users, enabling individuals to undergo the rehabilitation process by playing games. Two surveys were conducted to evaluate the satisfaction of the participants regarding the gaming system.Results: The results of the online survey among a larger population

  7. Simulations of collisions between N-body classical systems in interaction; Simulations de collisions entre systemes classiques a n-corps en interaction

    Energy Technology Data Exchange (ETDEWEB)

    Morisseau, Francois [Laboratoire de Physique Corpusculaire de CAEN, ENSICAEN, Universite de Caen Basse-Normandie, UFR des Sciences, 6 bd Marechal Juin, 14050 Caen Cedex (France)

    2006-05-15

    The Classical N-body Dynamics (CNBD) is dedicated to the simulation of collisions between classical systems. The 2-body interaction used here has the properties of the Van der Waals potential and depends on just a few parameters. This work has two main goals. First, some theoretical approaches assume that the dynamical stage of the collisions plays an important role. Moreover, colliding nuclei are supposed to present a 1. order liquid-gas phase transition. Several signals have been introduced to show this transition. We have searched for two of them: the bimodality of the mass asymmetry and negative heat capacity. We have found them and we give an explanation of their presence in our calculations. Second, we have improved the interaction by adding a Coulomb like potential and by taking into account the stronger proton-neutron interaction in nuclei. Then we have figured out the relations that exist between the parameters of the 2-body interaction and the properties of the systems. These studies allow us to fit the properties of the classical systems to those of the nuclei. In this manuscript the first results of this fit are shown. (author)

  8. Interactive robot control system and method of use

    Science.gov (United States)

    Sanders, Adam M. (Inventor); Reiland, Matthew J. (Inventor); Abdallah, Muhammad E. (Inventor); Linn, Douglas Martin (Inventor); Platt, Robert (Inventor)

    2012-01-01

    A robotic system includes a robot having joints, actuators, and sensors, and a distributed controller. The controller includes command-level controller, embedded joint-level controllers each controlling a respective joint, and a joint coordination-level controller coordinating motion of the joints. A central data library (CDL) centralizes all control and feedback data, and a user interface displays a status of each joint, actuator, and sensor using the CDL. A parameterized action sequence has a hierarchy of linked events, and allows the control data to be modified in real time. A method of controlling the robot includes transmitting control data through the various levels of the controller, routing all control and feedback data to the CDL, and displaying status and operation of the robot using the CDL. The parameterized action sequences are generated for execution by the robot, and a hierarchy of linked events is created within the sequence.

  9. Herd Behavior and Financial Crashes: An Interacting Particle System Approach

    Directory of Open Access Journals (Sweden)

    Vincenzo Crescimanna

    2016-01-01

    Full Text Available We provide an approach based on a modification of the Ising model to describe the dynamics of stock markets. Our model incorporates three different factors: imitation, the impact of external news, and private information; moreover, it is characterized by coupling coefficients, static in time, but not identical for each agent. By analogy with physical models, we consider the temperature parameter of the system, assuming that it evolves with memory of the past, hence considering how former news influences realized market returns. We show that a standard Ising potential assumption is not sufficient to reproduce the stylized facts characterizing financial markets; this is because it assigns low probabilities to rare events. Hence, we study a variation of the previous setting providing, also by concrete computations, new insights and improvements.

  10. Interaction in polysilazane/SiC powder systems

    Energy Technology Data Exchange (ETDEWEB)

    Boiteux, Y.P.

    1992-07-01

    Consolidation of ceramic precursor ceramic powder systems upon heating is investigated. A polysilazane (silicon nitride precursor) is chosen as ceramic precursor with a filler of a sub-micron SiC powder. A scheme to optimize the volume fraction of precursor is developed in order to maximize the density of the compacted samples in the green state. Different techniques are presented to improve the homogeneity of precursor distribution in the mixture. A microencapsulation technique is developed that leads to a uniform coating of precursor on individual SiC particles. Upon pyrolysis of systems with 20 wt% polysilazane, little shrinkage occurs. The SiC particles do not coarsen during the heat treatment. The precursor, upon pyrolysis, transforms into an amorphous ceramic phase that acts as a cement between SiC particles. This cement phase can remain amorphous up to 1500{degrees}C; and is best described as a siliconoxycarbide with or without traces of nitrogen. Elimination of nitrogen in the amorphous phase indicates that the filler material (SiC) has a strong influence on the pyrolysis behavior of the chosen polysilazane. The amorphous ceramic phase may crystallize between 1400 and 1500{degrees}C, and depending on the nature of the gas environment, the crystalline phases are SiC, Si or Si{sub 3}N{sub 4}. Mechanisms explaining the strength increase upon heat treatment are proposed. Redistribution of the precursor occurs by capillary forces or vapor phase diffusion and recondensation of volatile monomers. The confined pyrolysis of the precursor results in an increase of residual ceramic matter being decomposed inside the sample. Interfacial reaction between the native silica-rich surface layer on SiC particles and the precursor derived phase explains the high strength of the materials.

  11. Modeling and Detecting Feature Interactions among Integrated Services of Home Network Systems

    Science.gov (United States)

    Igaki, Hiroshi; Nakamura, Masahide

    This paper presents a framework for formalizing and detecting feature interactions (FIs) in the emerging smart home domain. We first establish a model of home network system (HNS), where every networked appliance (or the HNS environment) is characterized as an object consisting of properties and methods. Then, every HNS service is defined as a sequence of method invocations of the appliances. Within the model, we next formalize two kinds of FIs: (a) appliance interactions and (b) environment interactions. An appliance interaction occurs when two method invocations conflict on the same appliance, whereas an environment interaction arises when two method invocations conflict indirectly via the environment. Finally, we propose offline and online methods that detect FIs before service deployment and during execution, respectively. Through a case study with seven practical services, it is shown that the proposed framework is generic enough to capture feature interactions in HNS integrated services. We also discuss several FI resolution schemes within the proposed framework.

  12. Visual interaction: models, systems, prototypes. The Pictorial Computing Laboratory at the University of Rome La Sapienza.

    Science.gov (United States)

    Bottoni, Paolo; Cinque, Luigi; De Marsico, Maria; Levialdi, Stefano; Panizzi, Emanuele

    2006-06-01

    This paper reports on the research activities performed by the Pictorial Computing Laboratory at the University of Rome, La Sapienza, during the last 5 years. Such work, essentially is based on the study of humancomputer interaction, spans from metamodels of interaction down to prototypes of interactive systems for both synchronous multimedia communication and groupwork, annotation systems for web pages, also encompassing theoretical and practical issues of visual languages and environments also including pattern recognition algorithms. Some applications are also considered like e-learning and collaborative work.

  13. Multimedia And Internetworking Architecture Infrastructure On Interactive E-Learning System

    Science.gov (United States)

    Indah, K. A. T.; Sukarata, G.

    2018-01-01

    Interactive e-learning is a distance learning method that involves information technology, electronic system or computer as one means of learning system used for teaching and learning process that is implemented without having face to face directly between teacher and student. A strong dependence on emerging technologies greatly influences the way in which the architecture is designed to produce a powerful interactive e-learning network. In this paper analyzed an architecture model where learning can be done interactively, involving many participants (N-way synchronized distance learning) using video conferencing technology. Also used broadband internet network as well as multicast techniques as a troubleshooting method for bandwidth usage can be efficient.

  14. Wearable Vibration Based Computer Interaction and Communication System for Deaf

    Directory of Open Access Journals (Sweden)

    Mete Yağanoğlu

    2017-12-01

    Full Text Available In individuals with impaired hearing, determining the direction of sound is a significant problem. The direction of sound was determined in this study, which allowed hearing impaired individuals to perceive where sounds originated. This study also determined whether something was being spoken loudly near the hearing impaired individual. In this manner, it was intended that they should be able to recognize panic conditions more quickly. The developed wearable system has four microphone inlets, two vibration motor outlets, and four Light Emitting Diode (LED outlets. The vibration of motors placed on the right and left fingertips permits the indication of the direction of sound through specific vibration frequencies. This study applies the ReliefF feature selection method to evaluate every feature in comparison to other features and determine which features are more effective in the classification phase. This study primarily selects the best feature extraction and classification methods. Then, the prototype device has been tested using these selected methods on themselves. ReliefF feature selection methods are used in the studies; the success of K nearest neighborhood (Knn classification had a 93% success rate and classification with Support Vector Machine (SVM had a 94% success rate. At close range, SVM and two of the best feature methods were used and returned a 98% success rate. When testing our wearable devices on users in real time, we used a classification technique to detect the direction and our wearable devices responded in 0.68 s; this saves power in comparison to traditional direction detection methods. Meanwhile, if there was an echo in an indoor environment, the success rate increased; the echo canceller was disabled in environments without an echo to save power. We also compared our system with the localization algorithm based on the microphone array; the wearable device that we developed had a high success rate and it produced faster

  15. A TWO-PRODUCT INVENTORY SYSTEM WITH PRODUCT INTERACTION

    Directory of Open Access Journals (Sweden)

    J. Yadavalli

    2012-01-01

    Full Text Available

    ENGLISH ABSTRACT: In this paper, we study a two-component continuous review inventory system. We assume that demand occurs according to a Poisson process and that a demand can be satisfied only if both the components are available in the inventory. Back-orders are not permitted. We assume that the lead-time distribution of one product is arbitrary and the other is exponential. Identifying the underlying process as a semi-regeneration process we find the stationary distribution of the inventory level, the performance measures such as mean stationary rate of number of lost demands, the demands and the reorders made. A numerical example illustrates the results.

    AFRIKAANSE OPSOMMING: Die artikel ondersoek 'n tweekomponent- deurlopende oorsigvoorraadstelsel. Daar word aanvaar dat aanvraag 'n Poissonproses is en dat aanvraag slegs bevredig kan word indien beide die komponente in die voorraad beskikbaar is. Agterstallige bestellings word nie toegelaat nie. Daar word aanvaar dat die lewertydverdeling van die een produk arbitrêr en die ander eksponensieël is. Indien die onderliggende proses as 'n semigenerasieproses geïdentifiseer word, kan die stasionêre verspreiding van die voorraadvlak bepaal word. Maatstawwe van vertoning soos mediaan- stasionêre koers van die hoeveelheid verlore aanvraag, die aanvraag en herbestellings wat gedoen is word bepaal. 'n Numeriese voorbeeld illustreer die resultate.

  16. The interaction of pupil response with the vergence system.

    Science.gov (United States)

    Feil, Moritz; Moser, Barbara; Abegg, Mathias

    2017-11-01

    A gaze shift from a target at distance to a target at near leads to pupillary constriction. The regulation of this pupillary near response is ill known. We investigated the impact of accommodation, convergence, and proximity on the pupillary diameter. We recorded pupil size and vergence eye movements with the use of an infrared eye tracker. We determined the pupillary response in four conditions: (1) after a gaze shift from far to near without accommodation, (2) after a gaze shift from far to near with neither accommodation nor convergence, (3) after accommodation alone, and (4) after accommodation with convergence without a gaze shift to near. These responses were compared to the pupil response of a full near response and to a gaze shift from one far target to another. We found a reliable pupillary near response. The removal of both accommodation and convergence in gaze shift from far to near abolished the pupillary near response. Accommodation alone did not induce pupillary constriction, while convergence and accommodation together induced a pupil response similar to the full near response. The main trigger for the pupillary response seems to be convergence. Neither accommodation nor proximity alone induce a significant pupillary constriction. This suggests that the miosis of the near triad is closely coupled to the vergence system rather than being independently regulated.

  17. Semiclassical quantization of integrable systems of few interacting anyons in a strong magnetic field

    International Nuclear Information System (INIS)

    Sivan, N.; Levit, S.

    1992-01-01

    We present a semiclassical theory of charged interacting anyons in a strong magnetic field. We derive the appropriate generalization of the WKB quantization conditions and determine the corresponding wave functions for non separable integrable anyonic systems. This theory is applies to a system of two interacting anyons, two interacting anyons in the presence of an impurity and three interacting anyons. We calculate the dependence of the semiclassical energy levels on the statistical parameter and find regions in which dependence follows very different patterns. The semiclassical treatment allows to find the correlation between these patterns and the change in the character of the classical motion of the system. We also test the accuracy of the mean field approximation for low and high energy states of the three anyons. (author)

  18. Quantum statistics and squeezing for a microwave-driven interacting magnon system.

    Science.gov (United States)

    Haghshenasfard, Zahra; Cottam, Michael G

    2017-02-01

    Theoretical studies are reported for the statistical properties of a microwave-driven interacting magnon system. Both the magnetic dipole-dipole and the exchange interactions are included and the theory is developed for the case of parallel pumping allowing for the inclusion of the nonlinear processes due to the four-magnon interactions. The method of second quantization is used to transform the total Hamiltonian from spin operators to boson creation and annihilation operators. By using the coherent magnon state representation we have studied the magnon occupation number and the statistical behavior of the system. In particular, it is shown that the nonlinearities introduced by the parallel pumping field and the four-magnon interactions lead to non-classical quantum statistical properties of the system, such as magnon squeezing. Also control of the collapse-and-revival phenomena for the time evolution of the average magnon number is demonstrated by varying the parallel pumping amplitude and the four-magnon coupling.

  19. The Web System for Managing Interaction of E-Commerce Entities

    Directory of Open Access Journals (Sweden)

    Pursky Oleg I.

    2017-09-01

    Full Text Available The development and software implementation of the web system for managing interaction of e-commerce entities is described, and a technology for its use is proposed. The web system has a three-level software architecture and is designed to automate interaction between an online store and online consumers. Specific requirements for the web system for managing the interaction of entities in e-commerce determine the features of its architecture and the structure of interactive elements of the program interface in the context of the specific tasks and processes for automation of which it is created. The web application is designed to work with three groups of users and provides access to elements of control of the interaction depending on the level of access of a particular user. For each group of the web system users there implemented measures to ensure the security and reliability of procedures for conducting trading operations. Important aspects of the developed web system for managing interaction of entities in e-commerce are the automation of all payment mechanisms and procedures of forming routes for delivery of goods and cross-browser support for working in the Internet computer network, which provides all geographically distributed users with the access to its resources.

  20. Food-Energy Interactive Tradeoff Analysis of Sustainable Urban Plant Factory Production Systems

    OpenAIRE

    Li-Chun Huang; Yu-Hui Chen; Ya-Hui Chen; Chi-Fang Wang; Ming-Che Hu

    2018-01-01

    This research aims to analyze the food–energy interactive nexus of sustainable urban plant factory systems. Plant factory systems grow agricultural products within artificially controlled growing environment and multi-layer vertical growing systems. The system controls the supply of light, temperature, humidity, nutrition, water, and carbon dioxide for growing plants. Plant factories are able to produce consistent and high-quality agricultural products within less production space for urban a...