Spectroscopic classification of AT 2017cfd as a young Type Ia supernova

Science.gov (United States)

Vinko, J.; Wheeler, J. C.

2017-03-01

We report the spectroscopic observation of AT 2017cfd, a transient discovered by the Lick Observatory Supernova Search (LOSS) on 2017-03-16. A spectrum (range 3700-9300 Angstroms), taken with the new "Low Resolution Spectrograph-2" (LRS2) on the 10m Hobby-Eberly Telescope at McDonald Observatory by Steve Odewahn on 2017-03-18.16 UT, is similar to that of a Type Ia supernova before maximum light.

Spectroscopic Classification of SN 2018nt as a Reddened Type Ia Supernova

Science.gov (United States)

Vinko, J.; Szeged, U.; Wheeler, J. C.

2018-02-01

An optical spectrum (range 360-700 nm) of SN 2018nt (K2 C16-0043), was obtained with the "Low Resolution Spectrograph-2" (LRS2) on the 10m Hobby-Eberly Telescope at McDonald Observatory by S. Odewahn on 2018 Feb 05.20 UT. The spectrum is consistent with that of a heavily reddened Type Ia supernova (with Av > 2 mag) about 3 weeks after maximum light.

Two New Long-period Hot Subdwarf Binaries with Dwarf Companions

Science.gov (United States)

Barlow, Brad N.; Liss, Sandra E.; Wade, Richard A.; Green, Elizabeth M.

2013-07-01

Hot subdwarf stars with F-K main sequence binary companions have been known for decades, but the first orbital periods for such systems were published just recently. Current observations suggest that most have long periods, on the order of years, and that some are or once were hierarchical triple systems. As part of a survey with the Hobby-Eberly Telescope, we have been monitoring the radial velocities of several composite-spectra binaries since 2005 in order to determine their periods, velocities, and eccentricities. Here we present observations and orbital solutions for two of these systems, PG 1449+653 and PG 1701+359. Similar to the other sdB+F/G/K binaries with solved orbits, their periods are long, 909 and 734 days, respectively, and pose a challenge to current binary population synthesis models of hot subdwarf stars. Intrigued by their relatively large systemic velocities, we also present a kinematical analysis of both targets and find that neither is likely a member of the Galactic thin disk. Based on observations obtained with the Hobby-Eberly Telescope, which is a joint project of the University of Texas at Austin, the Pennsylvania State University, Stanford University, Ludwig-Maximilians-Universität München, and Georg-August-Universität Göttingen.

Astrometry, Radial Velocity, and Photometry: The HD 128311 System Remixed with Data from HST, HET, and APT

Science.gov (United States)

McArthur, Barbara. E.; Benedict, G. Fritz; Henry, Gregory W.; Hatzes, Artie; Cochran, William D.; Harrison, Tom E.; Johns-Krull, Chris; Nelan, Ed

2014-11-01

We have used high-cadence radial velocity measurements from the Hobby-Eberly Telescope with published velocities from the Lick 3 m Shane Telescope, combined with astrometric data from the Hubble Space Telescope (HST) Fine Guidance Sensors to refine the orbital parameters of the HD 128311 system, and determine an inclination of 55.°95 ± 14.°55 and true mass of 3.789 +0.924 -0.432 M JUP for HD 128311 c. The combined radial velocity data also reveal a short period signal which could indicate a third planet in the system with an Msin i of 0.133 ± 0.005 M JUP or stellar phenomena. Photometry from the T12 0.8 m automatic photometric telescope at the Fairborn Observatory and HST are used to determine a photometric period close to, but not within the errors of the radial velocity signal. We performed a cross-correlation bisector analysis of the radial velocity data to look for correlations with the photometric period and found none. Dynamical integrations of the proposed system show long-term stability with the new orbital parameters of over 10 million years. Our new orbital elements do not support the claims of HD 128311 b and c being in mean motion resonance. Based on observations made with the NASA/ESA Hubble Space Telescope, obtained at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS5-26555. Based on observations obtained with the Hobby-Eberly Telescope, which is a joint project of the University of Texas at Austin, the Pennsylvania State University, Stanford University, Ludwig-Maximilians-Universität München, and Georg-August-Universität Göttingen, and observations with T12 0.8 m automatic photoelectric telescope (APT) at Fairborn Observatory.

Spectroscopic classification of AT 2017byx as a Type Ia Supernova

Science.gov (United States)

Vinko, J.; Wheeler, J. C.; Sarneczky, K.; Szakats, R.; Szalai, T.; Szekely, P.; HETDEX Collaboration

2017-05-01

During the commissioning phase of the Hobby-Eberly Telescope Dark Energy Experiment (HETDEX) survey we observed AT 2017byx (ATLAS17bla, PS17bve) at R.A.=14:17:48.36 Dec.=+52:41:54.6 with the Visible Integral-field Replicable Unit Spectrograph (VIRUS) at McDonald Observatory on 2017-04-28.2 UT. The spectrum (range between 3500 and 5500 Angstroms) indicates that AT 2017byx is a Type Ia supernova.

Spectroscopic Classification of SN 2017ghm as a Type Ia Supernova

Science.gov (United States)

Vinko, J.; Wheeler, J. C.; Wang, X.; Li, W.; Li, Z.; Xiang, D.; Rui, L.; Lin, H.; Xu, Z.; Li, B.; Zhao, H.; Wang, L.; Tan, H.; Zhang, J.

2017-09-01

An optical spectrum (range 360-680 nm) of SN 2017ghm (=PTSS-17uyml), discovered by the PMO-Tsinghua Supernova Survey (PTSS, http://www.cneost.org/ptss/), was obtained with the new "Low Resolution Spectrograph-2" (LRS2) on the 10m Hobby-Eberly Telescope at McDonald Observatory by S. Rostopchin on 2017 Aug 31.17 UT. The spectrum is consistent with that of a heavily reddened Type Ia supernova (with Av > 2.3 mag) around maximum light.

[Pathological hobbies and interests in schizophrenia].

Science.gov (United States)

Sergeev, I I; Malinochka, S A

2008-01-01

Pathological hobbies have been studied in 82 inpatients with schizophrenia, 48 men and 34 women, aged 18-65 years. Inclusion criteria of pathology were (1) overvalued character of a hobby, (2) insufficient criticism towards this hobby, (3) fringe, singularity interests and methods of their realization; (4) inconsistency between the hobby and previous life experience, (5) low efficiency, (6) strong linkage with other psychopathological presentations, (7) chronological coincidence between the onset of pathological hobbies and schizophrenia manifestation or exacerbation, (8) susceptibility to progressive dynamics, (9) distinct social-maladaptive influence. Regarding the content, pathological hobbies are presented by creative art, scientific work, collecting, gambling, sport and health activities, "spiritual" development. Three clinical variants - obsessive-compulsive, overvalued and paranoic can be singled out by clinical presentations. The overvalued variant appears to be more favorable due to the predominantly adaptive social influence and weak relation to the dynamics of schizophrenia. Other variants are less productive exerting mostly decompensation effect with less favorable dynamics.

Radial Velocity Detection of Extra-Solar Planetary Systems

Science.gov (United States)

Cochran, William D.

2004-01-01

This NASA Origins Program grant supported four closely related research programs at The University of Texas at Austin: 1) The McDonald Observatory Planetary Search (MOPS) Program, using the McDonald Observatory 2.7m Harlan Smith telescope and its 2dcoude spectrometer, 2) A high-precision radial-velocity survey of Hyades dwarfs, using the Keck telescope and its HIRES spectrograph, 3) A program at McDonald Observatory to obtain spectra of the parent stars of planetary systems at R = 210,000, and 4) the start of high precision radial velocity surveys using the Hobby-Eberly Telescope. The most important results from NASA support of these research programs are described. A list of all papers published under support of this grant is included at the end.

Kepler-424 b: A "Lonely" Hot Jupiter that Found a Companion

Science.gov (United States)

Endl, Michael; Caldwell, Douglas A.; Barclay, Thomas; Huber, Daniel; Isaacson, Howard; Buchhave, Lars A.; Brugamyer, Erik; Robertson, Paul; Cochran, William D.; MacQueen, Phillip J.; Havel, Mathieu; Lucas, Phillip; Howell, Steve B.; Fischer, Debra; Quintana, Elisa; Ciardi, David R.

2014-11-01

Hot Jupiter systems provide unique observational constraints for migration models in multiple systems and binaries. We report on the discovery of the Kepler-424 (KOI-214) two-planet system, which consists of a transiting hot Jupiter (Kepler-424b) in a 3.31 day orbit accompanied by a more massive outer companion in an eccentric (e = 0.3) 223 day orbit. The outer giant planet, Kepler-424c, is not detected transiting the host star. The masses of both planets and the orbital parameters for the second planet were determined using precise radial velocity (RV) measurements from the Hobby-Eberly Telescope (HET) and its High Resolution Spectrograph (HRS). In stark contrast to smaller planets, hot Jupiters are predominantly found to be lacking any nearby additional planets; they appear to be "lonely". This might be a consequence of these systems having a highly dynamical past. The Kepler-424 planetary system has a hot Jupiter in a multiple system, similar to \\upsilon Andromedae. We also present our results for Kepler-422 (KOI-22), Kepler-77 (KOI-127), Kepler-43 (KOI-135), and Kepler-423 (KOI-183). These results are based on spectroscopic data collected with the Nordic Optical Telescope (NOT), the Keck 1 telescope, and HET. For all systems, we rule out false positives based on various follow-up observations, confirming the planetary nature of these companions. We performed a comparison with planetary evolutionary models which indicate that these five hot Jupiters have heavy element contents between 20 and 120 M ⊕. Based on observations obtained with the Hobby-Eberly Telescope, which is a joint project of the University of Texas at Austin, the Pennsylvania State University, Stanford University, Ludwig-Maximilians-Universität München, and Georg-August-Universität Göttingen.

Enjoying hobbies is related to desirable cardiovascular effects.

Science.gov (United States)

Saihara, Keishi; Hamasaki, Shuichi; Ishida, Sanemasa; Kataoka, Tetsuro; Yoshikawa, Akiko; Orihara, Koji; Ogawa, Masakazu; Oketani, Naoya; Fukudome, Tsuyoshi; Atsuchi, Nobuhiko; Shinsato, Takuro; Okui, Hideki; Kubozono, Takuro; Ichiki, Hitoshi; Kuwahata, So; Mizoguchi, Etsuko; Fujita, Shoji; Takumi, Takuro; Ninomiya, Yuichi; Tomita, Kaai; Tei, Chuwa

2010-03-01

An unhealthy lifestyle can increase the risk of cardiovascular disease. However, the mechanism by which lifestyle influences the development of cardiovascular disease remains unclear. Since coronary endothelial function is a predictor of cardiovascular prognosis, the goal of this study was to characterize the effect of enjoying hobbies on coronary endothelial function and cardiovascular outcomes. A total of 121 consecutive patients (76 men, 45 women) with almost normal coronary arteries underwent Doppler flow study of the left anterior descending coronary artery following sequential administration of papaverine, acetylcholine, and nitroglycerin. On the basis of responses to questionnaires, patients were divided into two groups; the Hobby group (n = 71) who enjoyed hobbies, and the Non-hobby group (n = 50) who had no hobbies. Cardiovascular outcomes were assessed at long-term follow-up using medical records or questionnaire surveys for major adverse cardiovascular events (MACE).The average follow-up period was 916 +/- 515 days. There were no significant differences in demographics when comparing the two groups. The percent change in coronary blood flow and coronary artery diameter induced by acetylcholine was significantly greater in the Hobby group than in the Non-hobby group (49% +/- 77% vs 25% +/- 37%, P hobbies was the only independent predictor of MACE (odds ratio 8.1 [95% confidence interval 1.60, 41.90], P = 0.01) among the variables tested. In the early stages of arteriosclerosis, enjoying hobbies may improve cardiovascular outcomes via its favorable effects on coronary endothelial function.

Regularities in frequency spacings of δ Scuti stars: the Kepler star KIC 9700322

DEFF Research Database (Denmark)

Breger, M.; Balona, L.; Lenz, P.

2011-01-01

In the faint star KIC 9700322 observed by the Kepler satellite, 76 frequencies with amplitudes from 14 to 29 000 ppm were detected. The two dominant frequencies at 9.79 and 12.57 d-1 (113.3 and 145.5 μHz), interpreted to be radial modes, are accompanied by a large number of combination frequencie...... with the Hobby-Eberly Telescope, which is a joint project of the University of Texas at Austin, the Pennsylvania State University, Stanford University, Ludwig-Maximilians-Universität München and Georg-August-Universität Göttingen....

EBER2 RNA-induced transcriptome changes identify cellular processes likely targeted during Epstein Barr Virus infection

Directory of Open Access Journals (Sweden)

Benecke Bernd-Joachim

2008-10-01

Full Text Available Abstract Background Little is known about the physiological role of the EBER1 and 2 nuclear RNAs during Epstein Barr viral infection. The EBERs are transcribed by cellular RNA Polymerase III and their strong expression results in 106 to 107 copies per EBV infected cell, making them reliable diagnostic markers for the presence of EBV. Although the functions of most of the proteins targeted by EBER RNAs have been studied, the role of EBERs themselves still remains elusive. Findings The cellular transcription response to EBER2 expression using the wild-type and an internal deletion mutant was determined. Significant changes in gene expression patterns were observed. A functional meta-analysis of the regulated genes points to inhibition of stress and immune responses, as well as activation of cellular growth and cytoskeletal reorganization as potential targets for EBER2 RNA. Different functions can be assigned to different parts of the RNA. Conclusion These results provide new avenues to the understanding of EBER2 and EBV biology, and set the grounds for a more in depth functional analysis of EBER2 using transcriptome activity measurements.

Velocity Dispersions Across Bulge Types

International Nuclear Information System (INIS)

Fabricius, Maximilian; Bender, Ralf; Hopp, Ulrich; Saglia, Roberto; Drory, Niv; Fisher, David

2010-01-01

We present first results from a long-slit spectroscopic survey of bulge kinematics in local spiral galaxies. Our optical spectra were obtained at the Hobby-Eberly Telescope with the LRS spectrograph and have a velocity resolution of 45 km/s (σ*), which allows us to resolve the velocity dispersions in the bulge regions of most objects in our sample. We find that the velocity dispersion profiles in morphological classical bulge galaxies are always centrally peaked while the velocity dispersion of morphologically disk-like bulges stays relatively flat towards the center--once strongly barred galaxies are discarded.

Revisiting ρ1 Cancri e: A New Mass Determination of the Transiting Super-Earth

Science.gov (United States)

Endl, Michael; Robertson, Paul; Cochran, William D.; MacQueen, Phillip J.; Brugamyer, Erik J.; Caldwell, Caroline; Wittenmyer, Robert A.; Barnes, Stuart I.; Gullikson, Kevin

2012-11-01

We present a mass determination for the transiting super-Earth ρ1 Cancri e based on nearly 700 precise radial velocity (RV) measurements. This extensive RV data set consists of data collected by the McDonald Observatory planet search and published data from Lick and Keck observatories. We obtained 212 RV measurements with the Tull Coudé Spectrograph at the Harlan J. Smith 2.7 m Telescope and combined them with a new Doppler reduction of the 131 spectra that we have taken in 2003-2004 with the High-Resolution Spectrograph (HRS) at the Hobby-Eberly Telescope for the original discovery of ρ1 Cancri e. Using this large data set we obtain a five-planet Keplerian orbital solution for the system and measure an RV semi-amplitude of K = 6.29 ± 0.21 m s-1 for ρ1 Cnc e and determine a mass of 8.37 ± 0.38 M ⊕. The uncertainty in mass is thus less than 5%. This planet was previously found to transit its parent star, which allowed them to estimate its radius. Combined with the latest radius estimate from Gillon et al., we obtain a mean density of ρ = 4.50 ± 0.20 g cm-3. The location of ρ1 Cnc e in the mass-radius diagram suggests that the planet contains a significant amount of volatiles, possibly a water-rich envelope surrounding a rocky core. Based partly on observations obtained with the Hobby-Eberly Telescope, which is a joint project of the University of Texas at Austin, the Pennsylvania State University, Stanford University, Ludwig-Maximilians-Universität München, and Georg-August-Universität Göttingen.

The cellular RNA-binding protein EAP recognizes a conserved stem-loop in the Epstein-Barr virus small RNA EBER 1.

Science.gov (United States)

Toczyski, D P; Steitz, J A

1993-01-01

EAP (EBER-associated protein) is an abundant, 15-kDa cellular RNA-binding protein which associates with certain herpesvirus small RNAs. We have raised polyclonal anti-EAP antibodies against a glutathione S-transferase-EAP fusion protein. Analysis of the RNA precipitated by these antibodies from Epstein-Barr virus (EBV)- or herpesvirus papio (HVP)-infected cells shows that > 95% of EBER 1 (EBV-encoded RNA 1) and the majority of HVP 1 (an HVP small RNA homologous to EBER 1) are associated with EAP. RNase protection experiments performed on native EBER 1 particles with affinity-purified anti-EAP antibodies demonstrate that EAP binds a stem-loop structure (stem-loop 3) of EBER 1. Since bacterially expressed glutathione S-transferase-EAP fusion protein binds EBER 1, we conclude that EAP binding is independent of any other cellular or viral protein. Detailed mutational analyses of stem-loop 3 suggest that EAP recognizes the majority of the nucleotides in this hairpin, interacting with both single-stranded and double-stranded regions in a sequence-specific manner. Binding studies utilizing EBER 1 deletion mutants suggest that there may also be a second, weaker EAP-binding site on stem-loop 4 of EBER 1. These data and the fact that stem-loop 3 represents the most highly conserved region between EBER 1 and HVP 1 suggest that EAP binding is a critical aspect of EBER 1 and HVP 1 function. Images PMID:8380232

LRS2: A New Integral Field Spectrograph for the HET

Science.gov (United States)

Tuttle, Sarah E.; Hill, Gary J.; Chonis, Taylor S.; Tonnesen, Stephanie

2016-01-01

Here we present LRS2 (Low Resolution Spectrograph) and highlight early science opportunities with the newly upgraded Hobby Eberly telescope (HET). LRS2 is a four-channel optical wavelength (370nm - 1micron) spectrograph based on two VIRUS unit spectrographs. This fiber-fed integral field spectrograph covers a 12" x 6" field of view, switched between the two units (one blue, and one red) at R~2000. We highlight design elements, including the fundamental modification to grisms (from VPH gratings in VIRUS) to access the higher resolution. We discuss early science opportunities, including investigating nearby "blue-bulge" spiral galaxies and their anomalous star formation distribution.

Hobby-related information-seeking behaviour of highly dedicated online museum visitors

DEFF Research Database (Denmark)

Skov, Mette

2013-01-01

collectors and liberal arts enthusiasts. Analysis showed that the two hobby classes have distinct profiles including differences in the nature of their knowledge acquisition. Results. Across the two hobby classes, participants can be characterised as special interest museum visitors pursuing a long......-standing interest or hobby. The identified information needs were surprisingly well-defined known item needs and only few exploratory information needs were identified. Participants stressed the importance of personal channels and the social context of the hobby. Conclusions. The present study contributes...

SECRETLY ECCENTRIC: THE GIANT PLANET AND ACTIVITY CYCLE OF GJ 328

International Nuclear Information System (INIS)

Robertson, Paul; Endl, Michael; Cochran, William D.; MacQueen, Phillip J.; Boss, Alan P.

2013-01-01

We announce the discovery of a ∼2 Jupiter-mass planet in an eccentric 11 yr orbit around the K7/M0 dwarf GJ 328. Our result is based on 10 years of radial velocity (RV) data from the Hobby-Eberly and Harlan J. Smith telescopes at McDonald Observatory, and from the Keck Telescope at Mauna Kea. Our analysis of GJ 328's magnetic activity via the Na I D features reveals a long-period stellar activity cycle, which creates an additional signal in the star's RV curve with amplitude 6-10 m s –1 . After correcting for this stellar RV contribution, we see that the orbit of the planet is more eccentric than suggested by the raw RV data. GJ 328b is currently the most massive, longest-period planet discovered around a low-mass dwarf

A meta-analysis of potential relationship between Epstein-Barr-Encoded-RNA (EBER and onset time of post-transplant lymphoproliferative disorders

Directory of Open Access Journals (Sweden)

Hossein Khedmat

2015-01-01

Full Text Available Epstein-Barr virus (EBV encodes two non-polyadenylated RNAs termed EBV-encoded RNAs (EBERs. In this study, we tried to find series in which data of EBER and onset time of post-transplant lymphoproliferative disorder (PTLD for patients have been documented to conduct a meta-analysis. A comprehensive search of the literature was performed by Pubmed and Google scholar to find reports indicating test results for EBER and PTLD onset in transplant patients. PTLD was considered "early onset" when it develops within the first post-transplant year. Finally, 265 patients from 15 studies have been included in the meta-analysis. The overall meta-analysis also showed a significant relation between EBER test positivity and early-onset PTLD development [relative risk (RR: 1.36; 95% CI: 1.16-1.59; P <0.001]. The i2 index was 49.8%. Our study suggests that PTLD lesions with positive EBER test are more likely to develop within the early post-transplant period. Since early-onset PTLD is supposed to have better prognosis, having a positive EBER test might not be a bad news. However, for having a precise conclusion, prospective studies are needed to be conducted.

VizieR Online Data Catalog: DIB 661.3nm in Cepheid spectra (Kashuba+, 2016)

Science.gov (United States)

Kashuba, S. V.; Andrievsky, S. M.; Chekhonadskikh, F. A.; Luck, R. E.; Kovtyukh, V. V.; Korotin, S. A.; Krelowski, J.; Galazutdinov, G. A.

2017-11-01

We used spectra of Northern hemisphere Cepheids obtained by REL - one of the co-authors of this paper, with the High Resolution Spectrograph of the Hobby-Eberly Telescope at the McDonald Observatory of the University of Texas at Austin (Texas, USA) with the resolving power of 30000, a typical signal-to-noise ratio of about 100, and wavelength range of 435-780nm. A total of 253 Cepheid spectra were used in the research. We performed an investigation of the 661.356 nm DIB profile in 253 spectra of 176 Cepheids. After removal of the blending YII line the EW of each DIB was calculated for each spectrum. (1 data file).

[A comparison of characteristics of pathologic hobbies in schizophrenic patients of different age].

Science.gov (United States)

Sergeev, I I; Deych, R V; Malinochka, S A

2016-01-01

To analyze age-related pathologic hobbies in patients with schizophrenia spectrum disorders. Forty-three inpatients, aged from 4 to 16 years, and 31 patients, aged from 18 to 65 years, were studied. Clinical/psychopathological analysis, psychological experiment and clinical statistics were used. Pathological hobbies substantially differed depending on the age (3-6, 7-15 and 18-65 years). In preschool age, hobbies were immature and infantile, arose autochthonously, their course was relatively stable and they had limited maladaptive effects. In junior school/teenager age, hobbies were more distinct and were associated with more diverse and mature realization patterns. Their origin was more depended on environmental factors, the course was persistent or attack-like with more pronounced and steady maladaptive effects. In some cases, there was a trend to pathological hobby progression. Abnormal hobbies in patients of mature age were the most diverse in their subjects and forms of realization as well as in their clinical variants and dynamic types. In the group of mature patients with schizophrenic spectrum disorders, there was a significantly higher percentage of psychotic forms of pathological hobbies.

Occupation, hobbies, and acute leukemia in adults.

Science.gov (United States)

Terry, Paul D; Shore, David L; Rauscher, Garth H; Sandler, Dale P

2005-10-01

Occupational and industrial exposures have been implicated in the etiology of leukemia, yet uncertainty remains regarding potential high risk occupations. We examined the associations between self-reported occupations and hobbies and acute leukemia risk using data from 811 cases and 637 controls participating in a case-control study in the U.S. and Canada. We found that several occupations may increase the risk of acute leukemia, particularly occupations related to petroleum products, rubber, nuclear energy, munitions, plastics, and electronics manufacturing. Differences were noted according to histological type. Other occupations and hobbies were not clearly associated with risk.

Hobbies of Retired People in the People's Republic of China: A Preliminary Study.

Science.gov (United States)

Hu, Jun-Chen

1990-01-01

Described and analyzed hobbies of over 500 individuals in the People's Republic of China. Results indicated there were significant differences between the hobbies of retired and younger people; reading was the hobby most preferred; and gender, age, education, and previous occupation were factors that most influenced the retired person's choice of…

Hobbies with solvent exposure and risk of non-Hodgkin lymphoma.

Science.gov (United States)

Colt, Joanne S; Hartge, Patricia; Davis, Scott; Cerhan, James R; Cozen, Wendy; Severson, Richard K

2007-05-01

Occupational exposure to solvents has been reported to increase non-Hodgkin lymphoma (NHL) risk in some, but not all, studies. In a population-based case-control study, we examined whether participation in selected hobbies involving solvent exposure increases NHL risk. We identified NHL cases diagnosed at ages 20-74 years between 1998 and 2000 in Iowa or metropolitan Los Angeles, Detroit, and Seattle. Controls were selected using random digit dialing or Medicare files. Computer-assisted personal interviews (551 cases, 462 controls) elicited data on model building, painting/silkscreening/artwork, furniture refinishing, and woodworking/home carpentry. Hobby participation (68% of cases, 69% of controls) was not associated with NHL risk (OR = 0.9, 95% CI = 0.7-1.2). Compared to people with none of the hobbies evaluated, those who built models had significantly lower risk (OR = 0.7, CI = 0.5-1.0), but risk did not vary with the number of years or lifetime hours. Risk estimates for the other hobbies were generally less than one, but the associations were not significant and there were no notable patterns with duration of exposure. Use of oil-based, acrylic, or water-based paints; paint strippers; polyurethane; or varnishes was not associated with NHL risk. We conclude that participation in hobbies involving exposure to organic solvents is unlikely to increase NHL risk.

Gifted Youth and Their Hobbies: An Exploration of Information Behavior

Science.gov (United States)

Carruth, Debi

2013-01-01

This study was conducted as a way to begin to fill a gap in the literature regarding young people and hobby pursuit. Through intensive exploratory research, the study sought to explicate the information behaviors of gifted young people related to their hobby pursuit. Focus groups and home visits were conducted and participants were given the…

DISCOVERY OF A WOLF-RAYET STAR THROUGH DETECTION OF ITS PHOTOMETRIC VARIABILITY

Energy Technology Data Exchange (ETDEWEB)

Littlefield, Colin [Law School, University of Notre Dame, Notre Dame, IN 46556 (United States); Garnavich, Peter; McClelland, Colin; Rettig, Terrence [Physics Department, University of Notre Dame, Notre Dame, IN 46556 (United States); Marion, G. H. [Harvard-Smithsonian Center for Astrophysics, Cambridge, MA 02138 (United States); Vinko, Jozsef [Department of Optics, University of Szeged (Hungary); Wheeler, J. Craig [Astronomy Department, University of Texas, Austin, TX 78712 (United States)

2012-06-15

We report the serendipitous discovery of a heavily reddened Wolf-Rayet star that we name WR 142b. While photometrically monitoring a cataclysmic variable, we detected weak variability in a nearby field star. Low-resolution spectroscopy revealed a strong emission line at 7100 A, suggesting an unusual object and prompting further study. A spectrum taken with the Hobby-Eberly Telescope confirms strong He II emission and an N IV 7112 A line consistent with a nitrogen-rich Wolf-Rayet star of spectral class WN6. Analysis of the He II line strengths reveals no detectable hydrogen in WR 142b. A blue-sensitive spectrum obtained with the Large Binocular Telescope shows no evidence for a hot companion star. The continuum shape and emission line ratios imply a reddening of E(B - V) = 2.2-2.6 mag. We estimate that the distance to WR 142b is 1.4 {+-} 0.3 kpc.

VizieR Online Data Catalog: H-band spectroscopic analysis of 25 bright M31 GCs (Sakari+, 2016)

Science.gov (United States)

Sakari, C. M.; Shetrone, M. D.; Schiavon, R. P.; Bizyaev, D.; Prieto, C. A.; Beers, T. C.; Caldwell, N.; Garcia-Hernandez, D. A.; Lucatello, S.; Majewski, S.; O'Connell, R. W.; Pan, K.; Strader, J.

2016-11-01

H-band spectra (1.51-1.69um) of the target clusters were obtained with the moderately high resolution (R=22500) APOGEE spectrograph on the 2.5m Telescope at Apache Point Observatory in 2011 and 2013. The details of the observations can be found in Majewski+ (2015arXiv150905420M) and Zasowski+ (2013AJ....146...81Z), including descriptions of the plates and fibers that were utilized for the observations. The high-resolution optical abundances from Colucci et al. (2009, J/ApJ/704/385 and 2014ApJ...797..116C) are supplemented with new results for five globular clusters (GCs). The new optical spectra were obtained in 2009 and 2010 with the High Resolution Spectrograph on the Hobby-Eberly Telescope at McDonald Observatory in Fort Davis, TX (R=30000; spectral coverage over ~5320-6290 and ~6360-7340Å in the blue and the red, respectively). (5 data files).

FIRST 'WINGED' AND X-SHAPED RADIO SOURCE CANDIDATES. II. NEW REDSHIFTS

International Nuclear Information System (INIS)

Cheung, C. C.; Healey, Stephen E.; Landt, Hermine; Jordan, Andres; Verdoes Kleijn, Gijs

2009-01-01

We report optical spectroscopic observations of X-shaped radio sources with the Hobby-Eberly Telescope and Multiple-Mirror Telescope, focused on the sample of candidates from the FIRST survey presented in a previous paper. A total of 27 redshifts were successfully obtained, 21 of which are new, including a newly identified candidate source of this type which is presented here. With these observations, the sample of candidates from the previous paper is over 50% spectroscopically identified. Two new broad emission-lined X-shaped radio sources are revealed, while no emission lines were detected in about one-third of the observed sources; a detailed study of the line properties is deferred to a future paper. Finally, to explore their relation to the Fanaroff-Riley division, the radio luminosities and host galaxy absolute magnitudes of a spectroscopically identified sample of 50 X-shaped radio galaxies are calculated to determine their placement in the Owen-Ledlow plane.

DISCOVERY OF A WOLF-RAYET STAR THROUGH DETECTION OF ITS PHOTOMETRIC VARIABILITY

International Nuclear Information System (INIS)

Littlefield, Colin; Garnavich, Peter; McClelland, Colin; Rettig, Terrence; Marion, G. H.; Vinkó, József; Wheeler, J. Craig

2012-01-01

We report the serendipitous discovery of a heavily reddened Wolf-Rayet star that we name WR 142b. While photometrically monitoring a cataclysmic variable, we detected weak variability in a nearby field star. Low-resolution spectroscopy revealed a strong emission line at 7100 Å, suggesting an unusual object and prompting further study. A spectrum taken with the Hobby-Eberly Telescope confirms strong He II emission and an N IV 7112 Å line consistent with a nitrogen-rich Wolf-Rayet star of spectral class WN6. Analysis of the He II line strengths reveals no detectable hydrogen in WR 142b. A blue-sensitive spectrum obtained with the Large Binocular Telescope shows no evidence for a hot companion star. The continuum shape and emission line ratios imply a reddening of E(B – V) = 2.2-2.6 mag. We estimate that the distance to WR 142b is 1.4 ± 0.3 kpc.

THE McDONALD OBSERVATORY PLANET SEARCH: NEW LONG-PERIOD GIANT PLANETS AND TWO INTERACTING JUPITERS IN THE HD 155358 SYSTEM

International Nuclear Information System (INIS)

Robertson, Paul; Endl, Michael; Cochran, William D.; MacQueen, Phillip J.; Brugamyer, Erik J.; Barnes, Stuart I.; Caldwell, Caroline; Wittenmyer, Robert A.; Horner, J.; Simon, Attila E.

2012-01-01

We present high-precision radial velocity (RV) observations of four solar-type (F7-G5) stars—HD 79498, HD 155358, HD 197037, and HD 220773—taken as part of the McDonald Observatory Planet Search Program. For each of these stars, we see evidence of Keplerian motion caused by the presence of one or more gas giant planets in long-period orbits. We derive orbital parameters for each system and note the properties (composition, activity, etc.) of the host stars. While we have previously announced the two-gas-giant HD 155358 system, we now report a shorter period for planet c. This new period is consistent with the planets being trapped in mutual 2:1 mean-motion resonance. We therefore perform an in-depth stability analysis, placing additional constraints on the orbital parameters of the planets. These results demonstrate the excellent long-term RV stability of the spectrometers on both the Harlan J. Smith 2.7 m telescope and the Hobby-Eberly telescope.

Engagement in reading and hobbies and risk of incident dementia: the MoVIES project.

Science.gov (United States)

Hughes, Tiffany F; Chang, Chung-Chou H; Vander Bilt, Joni; Ganguli, Mary

2010-08-01

To examine whether there is an association between engagement in reading and hobbies and dementia risk in late life. A total of 942 members of a population-based, prospective cohort study were followed biennially to identify incident dementia cases. Cox proportional hazards models were used to estimate the risk of dementia in relation to baseline total number of activities and time commitment to reading and hobbies. A lower risk for dementia was found for a greater number of activities and for a high (about 1 hour each day) compared with low (less than 30 minutes each day) weekly time commitment to hobbies, independent of covariates. Only the protective effect of hobbies remained after methods were used to minimize bias due to potential preclinical dementia. Engaging in hobbies for 1 or more hours every day might be protective against dementia in late life.

Isolation and characterization of the genes for two small RNAs of herpesvirus papio and their comparison with Epstein-Barr virus-encoded EBER RNAs.

Science.gov (United States)

Howe, J G; Shu, M D

1988-08-01

Genes for the Epstein-Barr virus-encoded RNAs (EBERs), two low-molecular-weight RNAs encoded by the human gammaherpesvirus Epstein-Barr virus (EBV), hybridize to two small RNAs in a baboon cell line that contains a similar virus, herpesvirus papio (HVP). The genes for the HVP RNAs (HVP-1 and HVP-2) are located together in the small unique region at the left end of the viral genome and are transcribed by RNA polymerase III in a rightward direction, similar to the EBERs. There is significant similarity between EBER1 and HVP-1 RNA, except for an insert of 22 nucleotides which increases the length of HVP-1 RNA to 190 nucleotides. There is less similarity between the sequences of EBER2 and HVP-2 RNA, but both have a length of about 170 nucleotides. The predicted secondary structure of each HVP RNA is remarkably similar to that of the respective EBER, implying that the secondary structures are important for function. Upstream from the initiation sites of all four RNA genes are several highly conserved sequences which may function in the regulation of transcription. The HVP RNAs, together with the EBERs, are highly abundant in transformed cells and are efficiently bound by the cellular La protein.

Commissioning a hobby cutting device for radiochromic film preparation.

Science.gov (United States)

Zolfaghari, Somayeh; Francis, Kirby E; Kairn, Tanya; Crowe, Scott B

2017-06-01

In addition to a high spatial resolution and well characterised dose response, one of the major advantages of radiochromic film as a dosimeter is that sheets of film can be cut into pieces suitable for use as calibration films, and for in vivo and phantom measurements. The cutting of film is typically done using scissors or a guillotine, and this process can be time-consuming, limited in precision, requires extensive handling and does not allow holes to be cut from the film without cutting from an existing edge. This study investigated the use of a Brother ScanNCut hobby cutting system for EBT3 film preparation. The optimal operating parameters (blade size, pressure, speed) that resulted in precise cuts with minimal delamination at cut edges were identified using test cutting patterns. These parameters were then used to cut a large film insert for a stereotactic head phantom for comparison against an insert cut with scissors. While the hobby cutting system caused a wider region of delamination at the film edge (1.8 mm) compared to scissors (1 mm), the hobby cutting system was found to be able to produce reproducible cuts more efficiently and more accurately than scissors. The use of the hobby cutting system is recommended for complex phantom inserts (containing sharp corners or holes for alignment rods) or in situations where large numbers of film pieces need to be prepared.

Detection and quantification of Epstein-Barr virus EBER1 in EBV-infected cells by fluorescent in situ hybridization and flow cytometry

Science.gov (United States)

Stowe, R. P.; Cubbage, M. L.; Sams, C. F.; Pierson, D. L.; Barrett, A. D.

1998-01-01

A rapid and highly sensitive fluorescent in situ hybridization (FISH) assay was developed to detect Epstein Barr virus (EBV)-infected cells in peripheral blood. Multiple fluorescein-labeled antisense oligonucleotide probes were designed to hybridize to the EBER1 transcript, which is highly expressed in latently infected cells. After a rapid (30 min) hybridization, the cells were analyzed by flow cytometry. EBER1 was detected in several positive control cell lines that have variable numbers of EBV genome copies. No EBER1 was detected in two known EBV-negative cell lines. Northern blot analyses confirmed the presence and quantity of EBER1 transcripts in each cell line. This method was used to quantify the number of EBV-infected cells in peripheral blood from a patient with chronic mononucleosis. These results indicate that EBV-infected cells can be detected at the single cell level, and that this assay can be used to quantify the number of EBV-infected cells in clinical samples.

THE MASS OF HD 38529c FROM HUBBLE SPACE TELESCOPE ASTROMETRY AND HIGH-PRECISION RADIAL VELOCITIES

International Nuclear Information System (INIS)

Benedict, G. Fritz; McArthur, Barbara E.; Bean, Jacob L.; Barnes, Rory; Harrison, Thomas E.; Hatzes, Artie; Martioli, Eder; Nelan, Edmund P.

2010-01-01

Hubble Space Telescope Fine Guidance Sensor astrometric observations of the G4 IV star HD 38529 are combined with the results of the analysis of extensive ground-based radial velocity (RV) data to determine the mass of the outermost of two previously known companions. Our new RVs obtained with the Hobby-Eberly Telescope and velocities from the Carnegie-California group now span over 11 yr. With these data we obtain improved RV orbital elements for both the inner companion, HD 38529b, and the outer companion, HD 38529c. We identify a rotational period of HD 38529 (P rot = 31.65 ± 0fd17) with Fine Guidance Sensor photometry. The inferred star spot fraction is consistent with the remaining scatter in velocities being caused by spot-related stellar activity. We then model the combined astrometric and RV measurements to obtain the parallax, proper motion, perturbation period, perturbation inclination, and perturbation size due to HD 38529c. For HD 38529c we find P = 2136.1 ± 0.3 d, perturbation semimajor axis α = 1.05 ± 0.06 mas, and inclination i = 48. 0 3 ± 3. 0 7. Assuming a primary mass M * = 1.48 M sun , we obtain a companion mass M c = 17.6 +1.5 -1.2 M Jup , 3σ above a 13 M Jup deuterium burning, brown dwarf lower limit. Dynamical simulations incorporating this accurate mass for HD 38529c indicate that a near-Saturn mass planet could exist between the two known companions. We find weak evidence of an additional low amplitude signal that can be modeled as a planetary-mass (∼0.17 M Jup ) companion at P ∼194 days. Including this component in our modeling lowers the error of the mass determined for HD 38529c. Additional observations (RVs and/or Gaia astrometry) are required to validate an interpretation of HD 38529d as a planetary-mass companion. If confirmed, the resulting HD 38529 planetary system may be an example of a 'Packed Planetary System'.

PLANETS AROUND THE K-GIANTS BD+20 274 AND HD 219415

International Nuclear Information System (INIS)

Gettel, S.; Wolszczan, A.; Niedzielski, A.; Nowak, G.; Adamów, M.; Zieliński, P.; Maciejewski, G.

2012-01-01

We present the discovery of planet-mass companions to two giant stars by the ongoing Penn State-Toruń Planet Search conducted with the 9.2 m Hobby-Eberly Telescope. The less massive of these stars, K5-giant BD+20 274, has a 4.2 M J minimum mass planet orbiting the star at a 578 day period and a more distant, likely stellar-mass companion. The best currently available model of the planet orbiting the K0-giant HD 219415 points to a ∼> Jupiter-mass companion in a 5.7 year, eccentric orbit around the star, making it the longest period planet yet detected by our survey. This planet has an amplitude of ∼18 m s –1 , comparable to the median radial velocity 'jitter', typical of giant stars.

Serious play: A comparative study of engagement and learning in hobby practices

Science.gov (United States)

Azevedo, Flavio Saraiva

This dissertation is concerned with human behavior usually attributed to individual interests. As conceptualized in experimental and educational psychology, an individual interest refers to a particular relationship (called an interest relationship) between a person and a set of topically related activities. Interest relationships are self-motivated, long-term, and relatively stable, though they might change over time. As an example, a teenager's enduring and self-motivated involvement with model rocketry reflects her individual interest in the topic or domain of rocketry. As an alternative to this formulation, I develop a practice-centered theory of persistent engagement---or, simply, a theory of persistence---in free-choice, self-motivated practices. Taken together, self-motivated, long-term persistence in a free-choice practice refers exactly to the same set of phenomena that is the purview of psychological theories of individual interests. Hobbies are prototypic of free-choice, self-motivated, extended pursuit practices and therefore are the focal object of study of this dissertation. The centerpiece of the theory I put forward is the grounded theoretical concept of lines of practice. A line of practice is a distinctive, recurrent pattern of engagement in a person's continued pursuit of a hobby. To return to the example above, our rocketry buff might have three lines of practice in her hobby---one related to designing and flying unusual rockets, the other related to designing and flying high-powered rockets, and yet a third line concerned with designing and flying low-powered models. Any particular line of practice entails a set of closely interrelated activities. For instance, designing and flying high-powered rockets might entail visiting particular hobby stores, becoming a member of particular rocketry clubs, and engaging in construction work. Designing and flying unusual rockets, on the other hand, might entail some very different activities (e

Die Literarisierung des entzifferten Ägypten. Wissenschaft und Fiktion im Roman Uarda (1877 von Georg Ebers (1837-1898

Directory of Open Access Journals (Sweden)

Lucia Mor

2014-06-01

Full Text Available Nel contesto dell’orientalismo ottocentesco riveste un ruolo significativo la produzione narrativa dell’egittologo berlinese Georg Ebers (1837-1898, i cui romanzi rientrano nella categoria del Professorenroman. Al confine fra letteratura e storiografia, le opere di ambientazione egizia di Ebers diedero origine ad una vera e propria egittomania e fecero conoscere ad un vasto pubblico di lettori figure, eventi, usi e costumi dell’antica terra del Nilo, a quel tempo oggetto di studio della prima generazione di egittologi tedeschi (Lepsius, Brugsch; ma la trasposizione letteraria dell’antico mondo egizio fu anche occasione per mettere a tema questioni scottanti di natura religiosa, politica e sociale del presente. L’analisi del romanzo Uarda, un successo stampato in migliaia di copie, intende non solo mettere a fuoco la Weltanschauung di Ebers, ma g anche contribuire a riscoprire uno scrittore che, seppur di valore mediocre dal punto di vista letterario, rappresenta un tassello significativo dello Zeitgeist guglielmino.

Astrometry, radial velocity, and photometry: the HD 128311 system remixed with data from HST, HET, and APT

International Nuclear Information System (INIS)

McArthur, Barbara E.; Benedict, G. Fritz.; Cochran, William D.; Henry, Gregory W.; Hatzes, Artie; Harrison, Tom E.; Johns-Krull, Chris; Nelan, Ed

2014-01-01

We have used high-cadence radial velocity measurements from the Hobby-Eberly Telescope with published velocities from the Lick 3 m Shane Telescope, combined with astrometric data from the Hubble Space Telescope (HST) Fine Guidance Sensors to refine the orbital parameters of the HD 128311 system, and determine an inclination of 55.°95 ± 14.°55 and true mass of 3.789 −0.432 +0.924 M JUP for HD 128311 c. The combined radial velocity data also reveal a short period signal which could indicate a third planet in the system with an Msin i of 0.133 ± 0.005 M JUP or stellar phenomena. Photometry from the T12 0.8 m automatic photometric telescope at the Fairborn Observatory and HST are used to determine a photometric period close to, but not within the errors of the radial velocity signal. We performed a cross-correlation bisector analysis of the radial velocity data to look for correlations with the photometric period and found none. Dynamical integrations of the proposed system show long-term stability with the new orbital parameters of over 10 million years. Our new orbital elements do not support the claims of HD 128311 b and c being in mean motion resonance.

WTS1 b: The first planet detected in the WFCAM Transit Survey

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Cruz P.

2013-04-01

Full Text Available We report the discovery of WTS1 b, the first extrasolar planet found by the WFCAM Transit Survey. For one of the most promising transiting candidates, high-resolution spectra taken at the Hobby-Eberly Telescope (HET allowed us to estimate the spectroscopic parameters of the host star, a late-F main sequence dwarf (V = 16.13, and to measure its radial velocity variations. The combined analysis of the light curves and spectroscopic data resulted in an orbital period of the companion of 3.35 days, a planetary mass of 4.01 ± 0.35 MJ, and a planetary radius of 1.49 +0.16-0.18 RJ. WTS1 b has one of the largest radius anomalies among the known hot Jupiters in the mass range 3–5 MJ.

White Dwarfs in the HET Dark Energy Experiment

Science.gov (United States)

Castanheira, B. G.; Winget, D. E.; Williams, K.; Montgomery, M. H.; Falcon, R. E.; Hermes, J. J.

2010-11-01

In the past decades, large scale surveys have discovered a large number of white dwarfs. For example, the Sloan Digital Sky Survey (SDSS) Data Release 7 [5] lists about 20 000 spectroscopically confirmed new white dwarfs. More than just a number, the new discoveries revealed different flavors of white dwarfs, including a new class of pulsators [7] and a larger percentage of stars with a magnetic field [4]. The HET Dark Energy Experiment (HETDEX) will use the 9.2 m Hobby-Eberly Telescope at McDonald Observatory and a set of 150 spectrographs to map the three-dimensional positions of one million galaxies. The main goal of the survey is to probe dark energy by observing the recent universe (2products. We expect to obtain spectra for about 10 000 white dwarfs in the next 3 to 4 years.

VIRUS instrument enclosures

Science.gov (United States)

Prochaska, T.; Allen, R.; Mondrik, N.; Rheault, J. P.; Sauseda, M.; Boster, E.; James, M.; Rodriguez-Patino, M.; Torres, G.; Ham, J.; Cook, E.; Baker, D.; DePoy, Darren L.; Marshall, Jennifer L.; Hill, G. J.; Perry, D.; Savage, R. D.; Good, J. M.; Vattiat, Brian L.

2014-08-01

The Visible Integral-Field Replicable Unit Spectrograph (VIRUS) instrument will be installed at the Hobby-Eberly Telescope† in the near future. The instrument will be housed in two enclosures that are mounted adjacent to the telescope, via the VIRUS Support Structure (VSS). We have designed the enclosures to support and protect the instrument, to enable servicing of the instrument, and to cool the instrument appropriately while not adversely affecting the dome environment. The system uses simple HVAC air handling techniques in conjunction with thermoelectric and standard glycol heat exchangers to provide efficient heat removal. The enclosures also provide power and data transfer to and from each VIRUS unit, liquid nitrogen cooling to the detectors, and environmental monitoring of the instrument and dome environments. In this paper, we describe the design and fabrication of the VIRUS enclosures and their subsystems.

Undergraduate Research and Education at MIT Haystack Observatory

Science.gov (United States)

Pratap, P.; Salah, J.

2000-05-01

The MIT Haystack Observatory Undergraduate Research Initiative is an NSF- funded program aimed at involving undergraduate students in active radio astronomical research. The project has two major thrusts - students get hands-on experience using a small radio telescope that has been developed at Haystack and which will be provided as a low cost kit early next year. Beta versions of this telescope are being built for a select group of institutions. The second component is a research experience with the Haystack 37-m telescope. Use of the 37-m telescope has ranged from classroom demonstrations to original research projects. The Small Radio Telescope (SRT) project consists of a 2m dish with a 1420 MHz receiver. The antenna has a two axis mount that provides full sky coverage. The telescope is intended to provide students and faculty with an introduction to radio astronomy and instrument calibration. Observations of the sun and the galactic HI line are possible with the current version of this telescope. The 37-m telescope program is aimed at providing students with a research experience that can result in publishable results. The telescope has also been used in providing students with an introduction to the scope of radio astronomical data including continuum and spectral line observations. Classroom demonstrations have also been tested with non-science majors. Extensive supporting materials for the project have been developed on the world wide web. These include a radio astronomy tutorial, hardware and software information about both telescopes and project descriptions. We also provide curriculum suggestions to aid faculty incorporate radio astronomy into their courses.

Inexpensive Demonstration of Diffraction-Limited Telescope from NASA Stratospheric Balloons

Science.gov (United States)

Young, Elliot

NASA s Balloon Program often flies payloads to altitudes of 120,000 ft or higher, above 99.5% of the atmosphere. At those altitudes, the imaging degradation due to atmospheric- induced wavefront errors is virtually zero. In 2009, the SUNRISE balloon mission quantified the wavefront errors with a Shack-Hartmann array and found no evidence of wavefront errors. This means that a large telescope on a balloon should be able to achieve diffraction-limited performance, provided it can be stabilized at a level that is finer than the diffraction limit. At visible wavelengths, the diffraction limit of a 1 or 2 m telescope is 0.1 arcsec or 0.05 arcsec, respectively. NASA recently demonstrated WASP (the Wallops Arc-Second Pointing system) on a balloon flight in October 2011, a coarse pointing system that kept a dummy telescope (24 ft long, 1500 lbs) stabilized at the 0.25 arcsec level. We propose to use an orthogonal transfer CCD (OTCCD) from MIT Lincoln Laboratory to improve the pointing to 0.05 arcsec, an order of magnitude better than the coarse pointing alone and sufficient to provide long integrations at the diffraction limit of a 2-m telescope. Imaging in visible wavelengths is an important new capability. Ground-based adaptive optics (AO) systems on 8-m and 10-m class telescope cannot effectively correct for atmospheric turbulence at wavelengths shorter than 1 μm; the atmospheric wavefront errors are larger at these wavelengths than in the infrared J-H-K bands. At present, only the Hubble Space Telescope can achieve 0.05 arcsec resolution images in visible wavelengths, a capability that is dramatically oversubscribed. With a camera based on an MIT/LL OTCCD, a 2-m balloon-borne telescope could match the spatial resolution of HST. Under this project (and in conjunction with a SWRI Internal Research proposal), we will perform ground tests of a motion-compensation camera based on an MIT/LL Orthogonal Transfer CCD (OTCCD). This device can shift charge in four directions

Hobby with Biochemistry: Use of active learning methodology in Biochemistry at the Medical School

Directory of Open Access Journals (Sweden)

S. R.T. Prado

2015-08-01

Full Text Available Introduction and objectives: The learning of Biochemistry is generally considered difficult by the graduates, because studies the molecular level the metabolism of living and it demands a great capacity for abstraction by students. Thus, researchers have tried alternative methods to provid an alternative study method. Materials and methods: 178 students of the School of Medicine, PUC-PR, that course the disciplines of Medical Biochemistry I and II, were divided into 50 groups, each with 3-4 students, and were have to draw up a hobby activity with a specific theme of the Biochemistry. The selected topics were, amino acids and proteins, enzymes, cellular respiration, glycogen metabolism, gluconeogenesis, lipid metabolism, metabolic integration, dyslipidemia and atherogenesis, pathophysiology of diabetes mellitus and metabolic syndrome, mechanisms of diabetes mellitus complications. The hobby activities chosen were direct, duplex, self-defined, cryptogram, bugs game. Both issues such as the type of hobby was drawn between groups. The groups had to: elaborate hobby; presents it to class orally, applying the questions prepared; printing and expose the hobby at the wall in the University; answer an evaluation regarding the preparation of work; and all groups should get together and organize one titled magazine "Hobby with Biochemistry" and deliver it printed. Results and conclusions: According the groups, the greatest difficulty was the adequacy of the questions posed in the required format, once they had only one issue and restricted space for the responses. Furthermore, the formatting was also identified as a point very difficult in activity elaboration. On the topic of learning through the development of work, and/or a new skill groups assigned grades ranging between 7.0 and 10.0 and about 90% of the groups attributed note 10 on satisfaction of seeing the work done and its ability to produce it. According to the results, the activity proved to be

Solvent oriented hobbies and the risk of systemic sclerosis.

Science.gov (United States)

Nietert, P J; Sutherland, S E; Silver, R M; Pandey, J P; Dosemeci, M

1999-11-01

To examine whether those participating in solvent oriented hobbies (SOH) are at greater risk of developing systemic sclerosis (SSc), and if the association is modified by the presence of the anti-Scl70 antibody. Patients with SSc and controls were recruited from a university hospital rheumatology clinic. Recreational hobby and occupational histories were obtained along with blood samples. Cumulative scores were created for participation in SOH. Logistic regression was used to calculate odds ratios associated with SOH exposure after adjustment for sex, age at diagnosis, and occupational solvent exposure, and to examine the association between SOH exposure and the presence of anti-Scl70. Solvent exposure based on hobbies and occupations was determined for 178 cases (141 women, 37 men) and 200 controls (138 women, 62 men). Overall participation in SOH was not associated with SSc. However, odds of high cumulative SOH exposure was 3 times greater in those patients with SSc testing positive for the anti-Scl70 antibody compared to patients testing negative (OR 2.9, 95% CI 1.1, 7.9), and twice as great as controls (OR 2.5, 95% CI 1.1, 5.9). While patients with SSc did not participate more often in SOH than controls over all, odds of high cumulative SOH exposure was greater among patients with SSc testing positive for anti-Scl70 compared to those testing negative and compared to controls. These results provide further evidence that environmental agents may play a role in the development of Ssc.

VizieR Online Data Catalog: Abundances in the local region. II. F, G, and K dwarfs (Luck+, 2017)

Science.gov (United States)

Luck, R. E.

2017-06-01

The McDonald Observatory 2.1m Telescope and Sandiford Cassegrain Echelle Spectrograph provided much of the observational data for this study. High-resolution spectra were obtained during numerous observing runs, from 1996 to 2010. The spectra cover a continuous wavelength range from about 484 to 700nm, with a resolving power of about 60000. The wavelength range used demands two separate observations--one centered at about 520nm, and the other at about 630nm. Typical S/N values per pixel for the spectra are more than 150. Spectra of 57 dwarfs were obtained using the Hobby-Eberly telescope and High-Resolution Spectrograph. The spectra have a resolution of 30000, spanning the wavelength range of 400 to 785nm. They also have very high signal-to-noise ratios, >300 per resolution element in numerous cases. The last set of spectra were obtained from the ELODIE Archive (Moultaka et al. 2004PASP..116..693M). These spectra are fully processed, including order co-addition, and have a continuous wavelength span of 400 to 680nm and a resolution of 42000. The ELODIE spectra utilized here all have S/N>75 per pixel. (6 data files).

Search for giant planets in M 67. IV. Survey results

Science.gov (United States)

Brucalassi, A.; Koppenhoefer, J.; Saglia, R.; Pasquini, L.; Ruiz, M. T.; Bonifacio, P.; Bedin, L. R.; Libralato, M.; Biazzo, K.; Melo, C.; Lovis, C.; Randich, S.

2017-07-01

Context. We present the results of a seven-year-long radial velocity survey of a sample of 88 main-sequence and evolved stars to reveal signatures of Jupiter-mass planets in the solar-age and solar-metallicity open cluster M 67. Aims: We aim at studying the frequency of giant planets in this cluster with respect to the field stars. In addition, our sample is also ideal to perform a long-term study to compare the chemical composition of stars with and without giant planets in detail. Methods: We analyzed precise radial velocity (RV) measurements obtained with the HARPS spectrograph at the European Southern Observatory (La Silla), the SOPHIE spectrograph at the Observatoire de Haute-Provence (France), the HRS spectrograph at the Hobby Eberly Telescope (Texas), and the HARPS-N spectrograph at the Telescopio Nazionale Galileo (La Palma). Additional RV data come from the CORALIE spectrograph at the Euler Swiss Telescope (La Silla). We conducted Monte Carlo simulations to estimate the occurrence rate of giant planets in our radial velocity survey. We considered orbital periods between 1.0 day and 1000 days and planet masses between 0.2 MJ and 10.0 MJ. We used a measure of the observational detection efficiency to determine the frequency of planets for each star. Results: All the planets previously announced in this RV campaign with their properties are summarized here: 3 hot Jupiters around the main-sequence stars YBP1194, YBP1514, and YBP401, and 1 giant planet around the evolved star S364. Two additional planet candidates around the stars YBP778 and S978 are also analyzed in the present work. We discuss stars that exhibit large RV variability or trends individually. For 2 additional stars, long-term trends are compatible with new binary candidates or substellar objects, which increases the total number of binary candidates detected in our campaign to 14. Based on the Doppler-detected planets discovered in this survey, we find an occurrence of giant planets of 18

TWO NEW LONG-PERIOD HOT SUBDWARF BINARIES WITH DWARF COMPANIONS

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Barlow, Brad N.; Wade, Richard A. [Department of Astronomy and Astrophysics, Pennsylvania State University, 525 Davey Lab, University Park, PA 16802 (United States); Liss, Sandra E. [Department of Astronomy, University of Virginia, P.O. Box 400325, Charlottesville, VA 22904-4325 (United States); Green, Elizabeth M., E-mail: bbarlow@psu.edu [Steward Observatory, University of Arizona, 933 N. Cherry Avenue, Tucson, AZ 85721 (United States)

2013-07-01

Hot subdwarf stars with F-K main sequence binary companions have been known for decades, but the first orbital periods for such systems were published just recently. Current observations suggest that most have long periods, on the order of years, and that some are or once were hierarchical triple systems. As part of a survey with the Hobby-Eberly Telescope, we have been monitoring the radial velocities of several composite-spectra binaries since 2005 in order to determine their periods, velocities, and eccentricities. Here we present observations and orbital solutions for two of these systems, PG 1449+653 and PG 1701+359. Similar to the other sdB+F/G/K binaries with solved orbits, their periods are long, 909 and 734 days, respectively, and pose a challenge to current binary population synthesis models of hot subdwarf stars. Intrigued by their relatively large systemic velocities, we also present a kinematical analysis of both targets and find that neither is likely a member of the Galactic thin disk.

TWO NEW LONG-PERIOD HOT SUBDWARF BINARIES WITH DWARF COMPANIONS

International Nuclear Information System (INIS)

Barlow, Brad N.; Wade, Richard A.; Liss, Sandra E.; Green, Elizabeth M.

2013-01-01

Hot subdwarf stars with F-K main sequence binary companions have been known for decades, but the first orbital periods for such systems were published just recently. Current observations suggest that most have long periods, on the order of years, and that some are or once were hierarchical triple systems. As part of a survey with the Hobby-Eberly Telescope, we have been monitoring the radial velocities of several composite-spectra binaries since 2005 in order to determine their periods, velocities, and eccentricities. Here we present observations and orbital solutions for two of these systems, PG 1449+653 and PG 1701+359. Similar to the other sdB+F/G/K binaries with solved orbits, their periods are long, 909 and 734 days, respectively, and pose a challenge to current binary population synthesis models of hot subdwarf stars. Intrigued by their relatively large systemic velocities, we also present a kinematical analysis of both targets and find that neither is likely a member of the Galactic thin disk.

Line profile variations in selected Seyfert galaxies

International Nuclear Information System (INIS)

Kollatschny, W; Zetzl, M; Ulbrich, K

2010-01-01

Continua as well as the broad emission lines in Seyfert 1 galaxies vary in different galaxies with different amplitudes on typical timescales of days to years. We present the results of two independent variability campaigns taken with the Hobby-Eberly Telescope. We studied in detail the integrated line and continuum variations in the optical spectra of the narrow-line Seyfert galaxy Mrk 110 and the very broad-line Seyfert galaxy Mrk 926. The broad-line emitting region in Mrk 110 has radii of four to 33 light-days as a function of the ionization degree of the emission lines. The line-profile variations are matched by Keplerian disk models with some accretion disk wind. The broad-line region in Mrk 926 is very small showing an extension of two to three light-days only. We could detect a structure in the rms line-profiles as well as in the response of the line profile segments of Mrk 926 indicating the BLR is structured.

"Talk, Talk and More Talk": Parental Perceptions of Young Children's Information Practices Related to Their Hobbies and Interests

Science.gov (United States)

Barriage, Sarah

2016-01-01

Introduction: This article explores parental perceptions of young children's everyday life information practices related to their hobbies and interests. Method: Thirty-one parents of children between the ages of four and eight years old completed a survey about their children's hobbies and interests. Questions were related to the nature of the…

Novel optical designs for consumer astronomical telescopes and their application to professional imaging

Science.gov (United States)

Wise, Peter; Hodgson, Alan

2006-06-01

Since the launch of the Hubble Space Telescope there has been widespread popular interest in astronomy. A further series of events, most notably the recent Deep Impact mission and Mars oppositions have served to fuel further interest. As a result more and more amateurs are coming into astronomy as a practical hobby. At the same time more sophisticated optical equipment is becoming available as the price to performance ratio become more favourable. As a result larger and better optical telescopes are now in use by amateurs. We also have the explosive growth in digital imaging technologies. In addition to displacing photographic film as the preferred image capture modality it has made the capture of high quality astronomical imagery more accessible to a wider segment of the astronomy community. However, this customer requirement has also had an impact on telescope design. There has become a greater imperative for wide flat image fields in these telescopes to take advantage of the ongoing advances in CCD imaging technology. As a result of these market drivers designers of consumer astronomical telescopes are now producing state of the art designs that result in wide, flat fields with optimal spatial and chromatic aberrations. Whilst some of these designs are not scalable to the larger apertures required for professional ground and airborne telescope use there are some that are eminently suited to make this transition.

Twin-Telescope Wettzell (TTW)

Science.gov (United States)

Hase, H.; Dassing, R.; Kronschnabl, G.; Schlüter, W.; Schwarz, W.; Lauber, P.; Kilger, R.

2007-07-01

delay measurements, Mark 5 Memo #043, MIT Haystack Observatory. Rogers, A.E.E. (2006). Some thoughts on the calibration of broadband geodetic VLBI, Mark 5 Memo #044, MIT Haystack Observatory. Rothacher M. (2006). GGOS: the IAG contribution to Earth observation, IGS Workshop 2006 "Perspectives and Visions for 2010 and beyond", May 8-12, Darmstadt, Germany Weinreb, S., Mandi, H. (2006). Pattern and Noise Tests of ETS-Lindgren 3164-05 Quadridge/Vivaldi Antenna, California Institute of Technology. Weinreb, S. (2007). Broadband feeds, E-mail, January. Welch, Wm. J. (2005). The Allen Telescope Array, URSI, UC Berkeley, January.

Woodworking injuries: a comparative study of work-related and hobby-related accidents.

Science.gov (United States)

Loisel, F; Bonin, S; Jeunet, L; Pauchot, J; Tropet, Y; Obert, L

2014-10-01

The primary objective of this study was to describe the injury characteristics and demographics of patients injured during woodworking activities, upon their arrival to the emergency department in a regional of France where this industry is prevalent. The secondary objective was to compare patient and injury characteristics for work-related and hobby-related accidents. A cohort of 87 patients who had suffered a woodworking accident over a two-year period was evaluated; 79 were available for follow-up. The context and circumstances of the accident, nature and location of the injuries and patient demographics were recorded. Hobby-related accidents accounted for two-thirds of the accidents (51/79). Most of the injured workers were either loggers (35%) or carpenters (46%). The hand was injured in 53 cases (67%). Work-related accidents resulted in significantly more serious consequences in terms of hospital stay, work stoppage, resumption of work or retraining than hobby-related accidents. For the workplace accidents, 86% occurred on new machines; more than 25% of the machines involved in accidents at home were over 15 years. Sixty-eight per cent of workers were wearing their safety gear, while only 31% of those injured during recreational woodworking wore the appropriate gear. Several elements of prevention should be improved: information about the need to maintain the equipment, protect the worker with suitable clothing, and learn which maneuvers are considered hazardous. Safety gear should be regularly inspected in the workplace. Copyright © 2014. Published by Elsevier SAS.

The Chemical Abundances of Stars in the Halo (CASH) Project. II. New Extremely Metal-poor Stars

Science.gov (United States)

Krugler, Julie A.; Frebel, A.; Roederer, I. U.; Sneden, C.; Shetrone, M.; Beers, T.; Christlieb, N.

2011-01-01

We present new abundance results from the Chemical Abundances of Stars in the Halo (CASH) project. The 500 CASH spectra were observed using the Hobby-Eberly Telescope in "snapshot" mode and are analyzed using an automated stellar parameter and abundance pipeline called CASHCODE. For the 20 most metal-poor stars of the CASH sample we have obtained high resolution spectra using the Magellan Telescope in order to test the uncertainties and systematic errors associated with the snapshot quality (i.e., R 15,000 and S/N 65) HET spectra and to calibrate the newly developed CASHCODE by making a detailed comparison between the stellar parameters and abundances determined from the high resolution and snapshot spectra. We find that the CASHCODE stellar parameters (effective temperature, surface gravity, metallicity, and microturbulence) agree well with the results of the manual analysis of the high resolution spectra. We present the abundances of three newly discovered stars with [Fe/H] ratios with alpha-enhancement and Fe-peak depletion and a range of n-capture elements. The full CASH sample will be used to derive statistically robust abundance trends and frequencies (e.g. carbon and n-capture), as well as placing constraints on nucleosynthetic processes that occurred in the early universe.

Converging migration routes of Eurasian hobbies Falco subbuteo crossing the African equatorial rain forest.

Science.gov (United States)

Strandberg, Roine; Klaassen, Raymond H G; Hake, Mikael; Olofsson, Patrik; Alerstam, Thomas

2009-02-22

Autumn migration of adult Eurasian hobbies Falco subbuteo from Europe to southern Africa was recorded by satellite telemetry and observed routes were compared with randomly simulated routes. Two non-random features of observed routes were revealed: (i) shifts to more westerly longitudes than straight paths to destinations and (ii) strong route convergence towards a restricted area close to the equator (1 degree S, 15 degrees E). The birds migrated south or southwest to approximately 10 degrees N, where they changed to south-easterly courses. The maximal spread between routes at 10 degrees N (2134 km) rapidly decreased to a minimum (67 km) close to the equator. We found a striking relationship between the route convergence and the distribution of continuous rainforest, suggesting that hobbies minimize flight distance across the forest, concentrating in a corridor where habitat may be more suitable for travelling and foraging. With rainforest forming a possible ecological barrier, many migrants may cross the equator either at 15 degrees E, similar to the hobbies, or at 30-40 degrees E, east of the rainforest where large-scale migration is well documented. Much remains to be understood about the role of the rainforest for the evolution and future of the trans-equatorial Palaearctic-African bird migration systems.

A PLANET IN A 0.6 AU ORBIT AROUND THE K0 GIANT HD 102272

International Nuclear Information System (INIS)

Niedzielski, A.; Gozdziewski, K.; Nowak, G.; Zielinski, P.; Wolszczan, A.; Konacki, M.

2009-01-01

We report the discovery of one or more planet-mass companions to the K0-giant HD 102272 with the Hobby-Eberly Telescope. In the absence of any correlation of the observed periodicities with the standard indicators of stellar activity, the observed radial velocity variations are most plausibly explained in terms of a Keplerian motion of at least one planet-mass body around the star. With an estimated stellar mass of 1.9 M sun , the minimum mass of the confirmed planet is 5.9 M J . The planet's orbit is characterized by a small but nonzero eccentricity e = 0.05 and a semimajor axis of 0.61 AU, which makes it the most compact planet discovered so far around GK spectral type giants. This detection adds to the existing evidence that, as predicted by theory, the minimum size of planetary orbits around intermediate-mass giants is affected by both planet-formation processes and stellar evolution. The currently available evidence of another planet around HD 102272 is insufficient to obtain an unambiguous two-orbit solution.

RADIAL VELOCITY OBSERVATIONS AND LIGHT CURVE NOISE MODELING CONFIRM THAT KEPLER-91b IS A GIANT PLANET ORBITING A GIANT STAR

International Nuclear Information System (INIS)

Barclay, Thomas; Huber, Daniel; Rowe, Jason F.; Quintana, Elisa V.; Endl, Michael; Cochran, William D.; MacQueen, Phillip J.; Foreman-Mackey, Daniel

2015-01-01

Kepler-91b is a rare example of a transiting hot Jupiter around a red giant star, providing the possibility to study the formation and composition of hot Jupiters under different conditions compared to main-sequence stars. However, the planetary nature of Kepler-91b, which was confirmed using phase-curve variations by Lillo-Box et al., was recently called into question based on a re-analysis of Kepler data. We have obtained ground-based radial velocity observations from the Hobby-Eberly Telescope and unambiguously confirm the planetary nature of Kepler-91b by simultaneously modeling the Kepler and radial velocity data. The star exhibits temporally correlated noise due to stellar granulation which we model as a Gaussian Process. We hypothesize that it is this noise component that led previous studies to suspect Kepler-91b to be a false positive. Our work confirms the conclusions presented by Lillo-Box et al. that Kepler-91b is a 0.73 ± 0.13 M Jup planet orbiting a red giant star

VizieR Online Data Catalog: Line list for seven target PAndAS clusters (Sakari+, 2015)

Science.gov (United States)

Sakari, C. M.; Venn, K. A.; Mackey, D.; Shetrone, M. D.; Dotter, A.; Ferguson, A. M. N.; Huxor, A.

2017-11-01

The targets were observed with the Hobby-Eberly Telescope (HET; Ramsey et al. 1998, Proc. SPIE, 3352, 34; Shetrone et al. 2007PASP..119..556S) at McDonald Observatory in Fort Davis, TX in 2011 and early 2012. The High Resolution Spectrograph (HRS; Tull 1998, Proc. SPIE, 3355, 387) was utilized with the 3-arcsec fibre and a slit width of 1 arcsec, yielding an instrumental spectral resolution of R=30000. With the 600 g/mm cross-disperser set to a central wavelength of 6302.9Å, wavelength coverages of ~5320-6290 and ~6360-7340Å were achieved in the blue and the red, respectively. The 3-arcsec fibre provided coverage of the clusters past their half-light radii; the additional sky fibres (located 10 arcsec from the central object fibre) provided simultaneous observations for sky subtraction. Exposure times were calculated to obtain a total signal-to-noise ratio (S/N)=80 (per resolution element), although not all targets received sufficient time to meet this goal. (2 data files).

Kommunikation mit Mitarbeitern

Science.gov (United States)

Spychala, Anne; Fleischmann, Jürgen

Kommunikation ist der Austausch von Nachrichten und Informationen zwischen Mitarbeitern eines Unternehmens (O'Hair et al. 1997). Dieser Austausch kann persönlich, aber z.B. auch per Telefon, E-Mail oder durch Computersysteme erfolgen. In diesem Kapitel betrachten wir die persönliche Kommunikation zwischen Vorgesetzten und Mitarbeitern. Zur persönlichen Kommunikation mit Mitarbeitern zählen sowohl formelle Gespräche mit Mitarbeitern als auch eher informelle Gespräche zwischen Tür und Angel. Die Gespräche können dabei mit einzelnen Mitarbeitern (z.B. jährliches Mitarbeitergespräch) oder mit Gruppen von Mitarbeitern (z.B. regelmäßige Projekt- oder Teambesprechungen) stattfinden.

Behandlung von Herzrhythmusstörungen mit Magnesium bei Patienten mit Herzinsuffizienz

Directory of Open Access Journals (Sweden)

Wink K

2002-01-01

Full Text Available Die medikamentöse Behandlung von Herzrhythmusstörungen ist unbefriedigend, da bei guter Wirksamkeit durch die Proarrhythmie eine Verbesserung der Prognose gefährdet und nicht gesichert ist. Man kann davon ausgehen, daß Magnesiumsalze keine arrhythmogene Effekte aufweisen. Bei Patienten mit einer Herzinsuffizienz besteht häufig ein Mg-Mangel, der durch gastrointestinale Störungen, neurohormonale Regulationen, aber auch durch die Therapie (Diuretika,Digitalisbedingt ist. An Patienten mit einer Herzinsuffizienz müßte sich demnach zeigen lassen, ob die Mg-Substitution einen antiarrhythmischen Effekt aufweist. In fünf placebokontrollierten Studien konnte gezeigt werden, daß sich teil weise signifikant und mit ausreichen der Aussagekraft (PowerArrhythmien bei Patienten mit Herzinsuffizienz durch orale und parenterale Gabe von Mg-Salzen reduzieren lassen. Trotz Einschränkungen wie z.B. inadäquates Design, fehlende Vermeidung von Bias, ungenügende Vergleichbarkeit der Behandlungsgruppen, inadäquate Auswertung und ungenügende Berücksichtigung der Spontanvariation läßt sich aufgrund der Ergebnisse der Studien die Hypothese aufstellen, daß Magnesiumsalze bei Patienten mit Herzinsuffizienz Herzrhythmusstörungen günstig beeinflussen können. Prospektive, randomisierte,verblindete und kontrollierte konfirmatorische Studien mit ausreichenden Fallzahlen sind jedoch notwendig, um diese Hypothese zu bestätigen.

A case-control study of childhood brain tumors and fathers' hobbies: a Children's Oncology Group study.

Science.gov (United States)

Rosso, Andrea L; Hovinga, Mary E; Rorke-Adams, Lucy B; Spector, Logan G; Bunin, Greta R

2008-12-01

A comprehensive case-control study was conducted to evaluate parental risk factors for medulloblastoma (MB) and primitive neuroectodermal tumor (PNET). This analysis was conducted to evaluate associations between fathers' hobbies and risk of their children developing MB/PNET. The hobbies chosen for study were those with similar exposures as occupations associated with childhood cancers. Cases were 318 subjects under six years of age at diagnosis between 1991 and 1997 and registered with the Children's Cancer Group. An equal number of controls were selected through random digit dialing and individually matched to cases. In multivariate analyses, a significant association was seen for lawn care with pesticides [during pregnancy: odds ratio (OR) = 1.6, 95% confidence interval (CI): 1.0, 2.5; after birth: OR = 1.8, 95% CI: 1.2, 2.8] and a weak association was seen for stripping paint [during pregnancy: OR = 1.4, 95% CI: 0.8, 2.6; after birth: OR = 1.4, 95% CI: 0.7, 2.6]. This study suggests that household exposures from hobbies, particularly pesticides, may increase risk of MB/PNET in children; previous research has been mostly limited to occupational exposures.

Marketing mit Youtube

OpenAIRE

Nufer, Gerd; Kaps, Anne

2017-01-01

Die Video-Plattform Youtube ist eine der meistbesuchten Webseiten weltweit. Youtube-Stars erreichen mit ihren Videos große Zuschauergruppen und können als Multiplikatoren für Werbebotschaften dienen. Sie sind oftmals Meinungsführer, denen hohes Vertrauen entgegengebracht wird, weshalb sie sich sehr gut für Influencer-Marketing eignen. Marketing mit Youtube ermöglicht eine offene, mehrwegige, schnelle und kostengünstige Kommunikation mit Kunden, insbesondere jüngeren. Unternehmen können sich d...

Family environment, hobbies and habits as psychosocial predictors of survival for surgically treated patients with breast cancer.

Science.gov (United States)

Tominaga, K; Andow, J; Koyama, Y; Numao, S; Kurokawa, E; Ojima, M; Nagai, M

1998-01-01

Many psychosocial factors have been reported to influence the duration of survival of breast cancer patients. We have studied how family members, hobbies and habits of the patients may alter their psychosocial status. Female patients with surgically treated breast cancer diagnosed between 1986 and 1995 at the Tochigi Cancer Center Hospital, who provided information on the above-mentioned factors, were used. Their subsequent physical status was followed up in the outpatients clinic. The Cox regression model was used to evaluate the relationship between the results of the factors examined and the duration of the patients' survival, adjusting for the patients' age, stage of disease at diagnosis and curability, as judged by the physician in charge after the treatment. The following factors were revealed to be significant with regard to the survival of surgically treated breast cancer patients: being a widow (hazard ratio 3.29; 95% confidence interval 1.32-8.20), having a hobby (hazard ratio 0.43; 95% confidence interval 0.23-0.82), number of hobbies (hazard ratio 0.64; 95% confidence interval 0.41-1.00), number of female children (hazard ratio 0.64; 95% confidence interval 0.42-0.98), smoker (hazard ratio 2.08; 95% confidence interval 1.02-4.26) and alcohol consumption (hazard ratio 0.10; 95% confidence interval 0.01-0.72). These results suggest that psychosocial factors, including the family environment, where patients receive emotional support from their spouse and children, hobbies and the patients' habits, may influence the duration of survival in surgically treated breast cancer patients.

Keeping venomous snakes in the Netherlands: a harmless hobby or a public health threat?

Science.gov (United States)

van Genderen, P J J; Slobbe, L; Koene, H; Mastenbroek, R D L; Overbosch, D

2013-10-01

To describe the incidence of venomous snakebites and the hospital treatment thereof (if any) amongst private individuals who keep venomous snakes as a hobby. Descriptive study. Private keepers of venomous snakes were invited via the social media Facebook, Hyves, Twitter, Google Plus, Linked In and two large discussion forums to fill in an online questionnaire on a purely voluntary and anonymous basis. In the period from 1 September 2012 to 31 December 2012, 86 questionnaires were completed by individuals who keep venomous snakes as a hobby. One-third of the venomous snake keepers stated that they had at some point been bitten by a venomous snake. Out of those, two-thirds needed hospital treatment and one-third of those bitten required at least one, sometimes more, doses of antiserum. The chances of being bitten increased the more venomous snakes a person kept. An inventory of the collections of venomous snakes being kept further revealed that no antiserum exists for 16 of the species, including for the most commonly held venomous snake, the coral cobra. Keeping venomous snakes as a hobby is not without danger. Although in the majority of snakebite cases no antiserum had to be administered, there is nevertheless a significant risk of morbidity and sequelae. Preventing snakebites in the first place remains the most important safety measure since there are no antiserums available for a substantial number of venomous snakes.

Preliminary analysis of surface displacement results in the creepdown irradiation experiment HOBBIE-1

International Nuclear Information System (INIS)

Hobson, D.O.

1979-01-01

This report presents the results of the eddy-current surface displacement measurements of Zircaloy cladding obtained during the HOBBIE-1 irradiation experiment in the HFR at ECN-Petten, the Netherlands. Raw creepdown data from the test were corrected through the use of reference coils incorporated in the eddy-current coil block in the experiment capsule. The corrected displacement results are compared with out-of-reactor results obtained under nominally identical conditions of pressure and temperature. Experiment HOBBIE-1 was run at 371 0 C and 13.1 MPa specimen external pressure for a total time of approximately 950 h. No gross cladding ovalization was obtained. This result differed from the relatively simple ovality found in the out-of-reactor test. Contact with the internal mandrel occurred between 400 and 500 h, compared with 375 h for a comparable out-of-reactor test. Average diameter decreases for both tests were similar. These results are discussed in detail

EARLY ULTRAVIOLET OBSERVATIONS OF A TYPE IIn SUPERNOVA (2007pk)

International Nuclear Information System (INIS)

Pritchard, T. A.; Roming, P. W. A.; Brown, P. J.; Kuin, N. P. M.; Oates, S. R.; Bayless, Amanda J.; Holland, S. T.; Immler, S.; Milne, P.

2012-01-01

We present some of the earliest UV observations of a Type IIn supernova (SN)—SN 2007pk, where UV and optical observations using Swift's Ultra-Violet/Optical Telescope began 3 days after discovery or ∼5 days after shock breakout. The SN observations commence at approximately maximum light in the UV and u-band filters, suggesting that the UV light curve peaks begin very rapidly after the initial explosion, and subsequently exhibit a linear decay of 0.20, 0.21, 0.16 mag day –1 in the UVOT uvw2, uvm2, uvw1 (λ c = 1928, 2246, 2600 Å) filters. Meanwhile the b- and v-band light curves begin approximately seven days before v-band peak and exhibit a shallow rise followed by a subsequent decay. A series of optical/near-IR spectra taken with the Hobby-Eberly Telescope at days 3-26 after discovery show spectra similar to that of the peculiar Type IIn 1998S. The emission from 2007pk falls below detection ∼20 days after discovery in the UV and 50 days in the optical, showing no sign of the long duration emission seen in other Type IIn SNe. We examine the physical and spectral characteristics of 2007pk and compare its UV light curve and decay rate with other Type II SNe.

THE HETDEX PILOT SURVEY. IV. THE EVOLUTION OF [O II] EMITTING GALAXIES FROM z ∼ 0.5 TO z ∼ 0

International Nuclear Information System (INIS)

Ciardullo, Robin; Gronwall, Caryl; Schneider, Donald P.; Zeimann, Gregory R.

2013-01-01

We present an analysis of the luminosities and equivalent widths of the 284 z 2 pilot survey for the Hobby-Eberly Telescope Dark Energy Experiment (HETDEX). By combining emission-line fluxes obtained from the Mitchell spectrograph on the McDonald 2.7 m telescope with deep broadband photometry from archival data, we derive each galaxy's dereddened [O II] λ3727 luminosity and calculate its total star formation rate. We show that over the last ∼5 Gyr of cosmic time, there has been substantial evolution in the [O II] emission-line luminosity function, with L* decreasing by ∼0.6 ± 0.2 dex in the observed function, and by ∼0.9 ± 0.2 dex in the dereddened relation. Accompanying this decline is a significant shift in the distribution of [O II] equivalent widths, with the fraction of high equivalent-width emitters declining dramatically with time. Overall, the data imply that the relative intensity of star formation within galaxies has decreased over the past ∼5 Gyr, and that the star formation rate density of the universe has declined by a factor of ∼2.5 between z ∼ 0.5 and z ∼ 0. These observations represent the first [O II]-based star formation rate density measurements in this redshift range, and foreshadow the advancements which will be generated by the main HETDEX survey.

Exploring the η Aquila System: Another Cepheid Parallax and Further Evidence for a Tertiary

Science.gov (United States)

Benedict, George Frederick; Barnes, Thomas G.; Evans, Nancy; Cochran, William; McArthur, Barbara E.; Harrison, Thomas E.

2018-01-01

We report progress towards a re-analysis of Hubble Space Telescope Fine Guidance Sensor astrometric data, originally acquired to determine a parallax for and absolute magnitudes of the classical Cepheid, η Aquila. This object was not included in past Cepheid Period-Luminosity Relation (PLR) work (Benedict et al. 2007, AJ, 133, 1810), because we had an insufficient number of epochs with which to establish a suspected and complicating companion orbit. Our new investigation is considerably aided by including a significant number of radial velocity measures (RV) from six sources, including new, high-quality Hobby-Eberly Telescope spectra. We first derive a 12 Fourier coefficient description of the Cepheid pulsation, solving for velocity offsets required to bring the six RV data sets into coincidence. We next model the RV residuals to that fit with an orbit. The resulting orbit has very high eccentricity. The astrometric residuals show only a very small perturbation, consistent with a prediction from the spectroscopic orbit. We finally include that orbit in a combined astrometry and radial velocity model. This modeling, similar to that presented in Benedict and Harrison (2017, AJ, 153, 258) yields a parallax, allowing inclusion of η Aquila in a PLR. It also establishes a Cepheid/companion mass ratio for the early-type star companion identified in IUE spectra (Evans 1991, ApJ, 372, 597).

Parents’ expectations and views of their child’s football hobby

OpenAIRE

Mikkonen, Matti

2014-01-01

The aim of this thesis is to describe the expectations and beliefs of parents regarding their child’s football hobby. Additionally I wanted to find out about the interaction between coaches and parents. The target group of this study was the parents of E-juniors, aged 11-12 years. The research was car-ried out with quantitative research method, and the sample group was 181 participants. The answers were collected with an internet survey in the winter of 2013. The results of this study in...

Age Determination in Some Ophisops elegans Mènètriès 1832 (Sauria: Lacertidae Populations Living in the Vicinity of Çanakkale and Akşehir-Eber

Directory of Open Access Journals (Sweden)

C. Varol Tok

2013-12-01

Full Text Available In this study, age determination was performed with the method of skeletochronology in 23 (13 ♂♂, 10 ♀♀ Ophisops elegans specimens collected from Çanakkale in the west of Turkey and 20 (10 ♂♂, 10 ♀♀ Ophisops elegans specimens collected from the vicinity of AkĢehir-Eber in the Central Anatolia Region. The mean ages of the specimens whose femur cross sections had been examined were determined to be 2.9±0.99 (1-4 in females and 2.85±0.68 (2-4 in males of the Çanakkale population and 3.9±1.19 (3-6 in females and 4.6±1.17 (3-6 in males of the AkĢehir-Eber population. The oldest age among the specimens was found to be six in two female and three male individuals of the AkĢehir-Eber population. When all specimens were evaluated altogether, the correlation between snoutvent length and age was computed as (r=0.572, p=0.008 in females and as (r=0.642, p=0.001 in males.

A CASE-CONTROL STUDY OF CHILDHOOD BRAIN TUMORS AND FATHERS’ HOBBIES — A CHILDREN’S ONCOLOGY GROUP STUDY

Science.gov (United States)

Rosso, Andrea L.; Hovinga, Mary E.; Rorke-Adams, Lucy B.; Spector, Logan G.; Bunin, Greta R.

2009-01-01

Objective A comprehensive case-control study was conducted to evaluate parental risk factors for medulloblastoma (MB) and primitive neuroectodermal tumor (PNET). This analysis was conducted to evaluate associations between fathers’ hobbies and risk of their children developing MB/PNET. The hobbies chosen for study were those with similar exposures as occupations associated with childhood cancers. Methods Cases were 318 subjects under 6 years of age at diagnosis between 1991-1997 and registered with the Children’s Cancer Group. An equal number of controls were selected through random digit dialing and individually matched to cases. Results In multivariate analyses, a significant association was seen for lawn care with pesticides [during pregnancy: odds ratio (OR) = 1.6, 95% confidence interval (CI): 1.0, 2.5; after birth: OR = 1.8, 95% CI: 1.2, 2.8] and a weak association was seen for stripping paint [during pregnancy: OR = 1.4, 95% CI: 0.8, 2.6; after birth: OR = 1.4, 95% CI: 0.7, 2.6]. Conclusions This study suggests that household exposures from hobbies, particularly pesticides, may increase risk of MB/PNET in children; previous research has been mostly limited to occupational exposures. PMID:18560982

Kepler-424 b: A 'lonely' hot Jupiter that found A companion

International Nuclear Information System (INIS)

Endl, Michael; Caldwell, Douglas A.; Barclay, Thomas; Huber, Daniel; Havel, Mathieu; Howell, Steve B.; Quintana, Elisa; Isaacson, Howard; Buchhave, Lars A.; Brugamyer, Erik; Robertson, Paul; Cochran, William D.; MacQueen, Phillip J.; Lucas, Phillip; Fischer, Debra; Ciardi, David R.

2014-01-01

Hot Jupiter systems provide unique observational constraints for migration models in multiple systems and binaries. We report on the discovery of the Kepler-424 (KOI-214) two-planet system, which consists of a transiting hot Jupiter (Kepler-424b) in a 3.31 day orbit accompanied by a more massive outer companion in an eccentric (e = 0.3) 223 day orbit. The outer giant planet, Kepler-424c, is not detected transiting the host star. The masses of both planets and the orbital parameters for the second planet were determined using precise radial velocity (RV) measurements from the Hobby-Eberly Telescope (HET) and its High Resolution Spectrograph (HRS). In stark contrast to smaller planets, hot Jupiters are predominantly found to be lacking any nearby additional planets; they appear to be l onely . This might be a consequence of these systems having a highly dynamical past. The Kepler-424 planetary system has a hot Jupiter in a multiple system, similar to υ Andromedae. We also present our results for Kepler-422 (KOI-22), Kepler-77 (KOI-127), Kepler-43 (KOI-135), and Kepler-423 (KOI-183). These results are based on spectroscopic data collected with the Nordic Optical Telescope (NOT), the Keck 1 telescope, and HET. For all systems, we rule out false positives based on various follow-up observations, confirming the planetary nature of these companions. We performed a comparison with planetary evolutionary models which indicate that these five hot Jupiters have heavy element contents between 20 and 120 M ⊕ .

Kepler-424 b: A 'lonely' hot Jupiter that found A companion

Energy Technology Data Exchange (ETDEWEB)

Endl, Michael [McDonald Observatory, The University of Texas at Austin, Austin, TX 78712 (United States); Caldwell, Douglas A.; Barclay, Thomas; Huber, Daniel; Havel, Mathieu; Howell, Steve B.; Quintana, Elisa [NASA Ames Research Center, Moffett Field, CA 94035 (United States); Isaacson, Howard [Department of Astronomy, University of California, Berkeley, CA 94720 (United States); Buchhave, Lars A. [Harvard-Smithsonian Center for Astrophysics, Cambridge, MA 02138 (United States); Brugamyer, Erik [Department of Astronomy, The University of Texas at Austin, Austin, TX 78712 (United States); Robertson, Paul [Department of Astronomy and Astrophysics, Center for Exoplanets and Habitable Worlds, Pennsylvania State University (United States); Cochran, William D.; MacQueen, Phillip J. [McDonald Observatory and Department of Astronomy, The University of Texas at Austin, Austin, TX 78712 (United States); Lucas, Phillip [Centre for Astrophysics Research, University of Hertfordshire, College Lane, Hatfield AL10 9AB (United Kingdom); Fischer, Debra [Department of Astronomy, Yale University (United States); Ciardi, David R. [NASA Exoplanet Science Institute, California Institute of Technology, Pasadena, CA 91125 (United States)

2014-11-10

Hot Jupiter systems provide unique observational constraints for migration models in multiple systems and binaries. We report on the discovery of the Kepler-424 (KOI-214) two-planet system, which consists of a transiting hot Jupiter (Kepler-424b) in a 3.31 day orbit accompanied by a more massive outer companion in an eccentric (e = 0.3) 223 day orbit. The outer giant planet, Kepler-424c, is not detected transiting the host star. The masses of both planets and the orbital parameters for the second planet were determined using precise radial velocity (RV) measurements from the Hobby-Eberly Telescope (HET) and its High Resolution Spectrograph (HRS). In stark contrast to smaller planets, hot Jupiters are predominantly found to be lacking any nearby additional planets; they appear to be {sup l}onely{sup .} This might be a consequence of these systems having a highly dynamical past. The Kepler-424 planetary system has a hot Jupiter in a multiple system, similar to υ Andromedae. We also present our results for Kepler-422 (KOI-22), Kepler-77 (KOI-127), Kepler-43 (KOI-135), and Kepler-423 (KOI-183). These results are based on spectroscopic data collected with the Nordic Optical Telescope (NOT), the Keck 1 telescope, and HET. For all systems, we rule out false positives based on various follow-up observations, confirming the planetary nature of these companions. We performed a comparison with planetary evolutionary models which indicate that these five hot Jupiters have heavy element contents between 20 and 120 M {sub ⊕}.

SUBSTELLAR-MASS COMPANIONS TO THE K-GIANTS HD 240237, BD +48 738, AND HD 96127

International Nuclear Information System (INIS)

Gettel, S.; Wolszczan, A.; Niedzielski, A.; Nowak, G.; Adamów, M.; Zieliński, P.; Maciejewski, G.

2012-01-01

We present the discovery of substellar-mass companions to three giant stars by the ongoing Penn State-Toruń Planet Search conducted with the 9.2 m Hobby-Eberly Telescope. The most massive of the three stars, K2-giant HD 240237, has a 5.3 M J minimum mass companion orbiting the star at a 746 day period. The K0-giant BD +48 738 is orbited by a ≥0.91 M J planet which has a period of 393 days and shows a nonlinear, long-term radial velocity (RV) trend that indicates a presence of another, more distant companion, which may have a substellar mass or be a low-mass star. The K2-giant HD 96127 has a ≥4.0 M J mass companion in a 647 day orbit around the star. The two K2-giants exhibit a significant RV noise that complicates the detection of low-amplitude, periodic variations in the data. If the noise component of the observed RV variations is due to solar-type oscillations, we show, using all the published data for the substellar companions to giants, that its amplitude is anti-correlated with stellar metallicity.

Stellar kinematics and populations out to 1.5 effective radii in the elliptical galaxy NGC 4636

International Nuclear Information System (INIS)

Pu Shibi; Han Zhanwen

2011-01-01

We present high quality long slit spectra along the major and minor axes out to 1.5 effective radii of the massive galaxy NGC 4636 taken by the Hobby-Eberly Telescope. Using the Fourier Correlation Quotient method, we measured the stellar line-of-sight velocity distribution along the axes. Furthermore, six Lick/IDS indices (Hβ, Mgb, Fe 5015 , Fe 5270 , Fe 5335 , Fe 5406 ) are derived from the clean spectrum. By comparing the measured absorption line strengths with the predictions of Simple Stellar Population (SSP) models, we derived ages, total metallicity and α abundance profiles of the galaxy. This galaxy presents old and [α/Fe] overabundant stellar populations. Indeed, using the SSP model, we obtained the broadband color profiles. The theoretical colors match well with the measured colors and present red sharp peaks at the galaxy center. The sharp peaks of the colors are mainly shaped by the high metallicity in the galaxy's center. Interestingly, the galaxy has steep negative metallicity gradients, but the trend flattens outwards. This result likely suggests that the center and outer regions of the galaxy formed through different formation processes.

Using ISS to develop telescope technology

Science.gov (United States)

Saenz-Otero, Alvar; Miller, David W.

2005-08-01

Future space telescope missions concepts have introduced new technologies such as precision formation flight, optical metrology, and segmented mirrors. These new technologies require demonstration and validation prior to deployment in final missions such as the James Webb Space Telescope, Terrestrial Planet Finder, and Darwin. Ground based demonstrations do not provide the precision necessary to obtain a high level of confidence in the technology; precursor free flyer space missions suffer from the same problems as the final missions. Therefore, this paper proposes the use of the International Space Station as an intermediate research environment where these technologies can be developed, demonstrated, and validated. The ISS provides special resources, such as human presence, communications, power, and a benign atmosphere which directly reduce the major challenges of space technology maturation: risk, complexity, cost, remote operations, and visibility. Successful design of experiments for use aboard the space station, by enabling iterative research and supporting multiple scientists, can further reduce the effects of these challenges of space technology maturation. This paper presents results of five previous MIT Space Systems Laboratory experiments aboard the Space Shuttle, MIR, and the ISS to illustrate successful technology maturation aboard these facilities.

REVISITING ρ1 CANCRI e: A NEW MASS DETERMINATION OF THE TRANSITING SUPER-EARTH

International Nuclear Information System (INIS)

Endl, Michael; Cochran, William D.; MacQueen, Phillip J.; Barnes, Stuart I.; Robertson, Paul; Brugamyer, Erik J.; Caldwell, Caroline; Gullikson, Kevin; Wittenmyer, Robert A.

2012-01-01

We present a mass determination for the transiting super-Earth ρ 1 Cancri e based on nearly 700 precise radial velocity (RV) measurements. This extensive RV data set consists of data collected by the McDonald Observatory planet search and published data from Lick and Keck observatories. We obtained 212 RV measurements with the Tull Coudé Spectrograph at the Harlan J. Smith 2.7 m Telescope and combined them with a new Doppler reduction of the 131 spectra that we have taken in 2003-2004 with the High-Resolution Spectrograph (HRS) at the Hobby-Eberly Telescope for the original discovery of ρ 1 Cancri e. Using this large data set we obtain a five-planet Keplerian orbital solution for the system and measure an RV semi-amplitude of K = 6.29 ± 0.21 m s –1 for ρ 1 Cnc e and determine a mass of 8.37 ± 0.38 M ⊕ . The uncertainty in mass is thus less than 5%. This planet was previously found to transit its parent star, which allowed them to estimate its radius. Combined with the latest radius estimate from Gillon et al., we obtain a mean density of ρ = 4.50 ± 0.20 g cm –3 . The location of ρ 1 Cnc e in the mass-radius diagram suggests that the planet contains a significant amount of volatiles, possibly a water-rich envelope surrounding a rocky core.

The Mitchell Spectrograph: Studying Nearby Galaxies with the VIRUS Prototype

Directory of Open Access Journals (Sweden)

Guillermo A. Blanc

2013-01-01

Full Text Available The Mitchell Spectrograph (a.k.a. VIRUS-P on the 2.7 m Harlan J. Smith telescope at McDonald Observatory is currently the largest field of view (FOV integral field unit (IFU spectrograph in the world (1.7′×1.7′. It was designed as a prototype for the highly replicable VIRUS spectrograph which consists of a mosaic of IFUs spread over a 16′ diameter FOV feeding 150 spectrographs similar to the Mitchell. VIRUS will be deployed on the 9.2 meter Hobby-Eberly Telescope (HET and will be used to conduct the HET Dark Energy Experiment (HETDEX. Since seeing first light in 2007 the Mitchell Spectrograph has been widely used, among other things, to study nearby galaxies in the local universe where their internal structure and the spatial distribution of different physical parameters can be studied in great detail. These observations have provided important insight into many aspects of the physics behind the formation and evolution of galaxies and have boosted the scientific impact of the 2.7 meter telescope enormously. Here I review the contributions of the Mitchell Spectrograph to the study of nearby galaxies, from the investigation the spatial distribution of dark matter and the properties of supermassive black holes, to the studies of the process of star formation and the chemical composition of stars and gas in the ISM, which provide important information regarding the formation and evolution of these systems. I highlight the fact that wide field integral field spectrographs on small and medium size telescopes can be powerful cost effective tools to study the astrophysics of galaxies. Finally I briefly discuss the potential of HETDEX for conducting studies on nearby galaxies. The survey parameters make it complimentary and competitive to ongoing and future surveys like SAMI and MANGA.

Tracking Advanced Planetary Systems (TAPAS) with HARPS-N. VI. HD 238914 and TYC 3318-01333-1: two more Li-rich giants with planets

Science.gov (United States)

Adamów, M.; Niedzielski, A.; Kowalik, K.; Villaver, E.; Wolszczan, A.; Maciejewski, G.; Gromadzki, M.

2018-05-01

Context. We present the latest results of our search for planets with HARPS-N at the 3.6 m Telescopio Nazionale Galileo under the Tracking Advanced Planetary Systems project: an in-depth study of the 15 most Li abundant giants from the PennState - Toruń Planet Search sample. Aims: Our goals are first, to obtain radial velocities of the most Li-rich giants we identified in our sample to search for possible low-mass substellar companions, and second, to perform an extended spectral analysis to define the evolutionary status of these stars. Methods: This work is based on high-resolution spectra obtained with the Hobby-Eberly Telescope and its High Resolution Spectrograph, and with the HARPS-N spectrograph at the Telescopio Nazionale Galileo. Two stars, HD 181368 and HD 188214, were also observed with UVES at the VLT to determine beryllium abundances. Results: We report i) the discovery of two new planetary systems around the Li-rich giant stars: HD 238914 and TYC 3318-01333-1 (a binary system); ii) reveal a binary Li-rich giant, HD 181368; iii) although our current phase coverage is not complete, we suggest the presence of planetary mass companions around TYC 3663-01966-1 and TYC 3105-00152-1; iv) we confirm the previous result for BD+48 740 and present updated orbital parameters, and v) we find a lack of a relation between the Li enhancement and the Be abundance for the stars HD 181368 and HD 188214, for which we acquired blue spectra. Conclusions: We found seven stars with stellar or potential planetary companions among the 15 Li-rich giant stars. The binary star frequency of the Li-rich giants in our sample appears to be normal, but the planet frequency is twice that of the general sample, which suggests a possible connection between hosting a companion and enhanced Li abundance in giant stars. We also found most of the companions orbits to be highly eccentric. Based on observations obtained with the Hobby-Eberly Telescope, which is a joint project of the

Sport, free time and hobbies in people with spinal cord injury.

Science.gov (United States)

Sale, P; Mazzarella, F; Pagliacci, M C; Aito, S; Agosti, M; Franceschini, M

2012-06-01

Prospective, multicenter follow-up (F-U) observational study. To investigate the changes in participation and sports practice of people after spinal cord injury (SCI) and their impact on perceived quality of life (QoL). The questionnaire investigated the health status and management of clinical conditions and attendance of social integration, occupation, autonomy, car driving, sentimental relationships and perceived QoL in a SCI population 4 years after the first rehabilitation hospitalization. Respondents were 403, 83.4% male; 39% was tetraplegic. At F-U, 42.1% worked and studied, 42.2% still held their jobs or studies, and 69% drove the car. In all, 77.2% had bowel continence and 40.4% urinary continence. The results showed that for the 68.2% of respondents, the attendance of friends, relatives and colleagues during their free time was the same or increased compared with the time before the injury, whereas 31.8% showed a decrease. The amount of time the 52.1% of respondents left home was the same or increased compared with before the trauma, whereas 50.6% of the respondents said that the time they were engaged in hobbies was either the same or increased. SCI people who perceived their QoL as being higher, and whose attendance, autonomy and time was increased in respect to hobbies, were mainly men with an age range between 36 and 40 years, unmarried, paraplegic and with A-B Asia Score. Regarding the amount of time dedicated to practicing sports, the only difference was the most of that respondents, who indicated a decrease, were women.

Rigiscan®-Monitoring der Erektion unter audiovisueller sexueller Stimulation ohne/mit Viagra™ bei Patienten mit erektiler Dysfunktion

Directory of Open Access Journals (Sweden)

Perabo FGE

2000-01-01

Full Text Available Die orale Medikation mit Sildenafil (Viagra™ hat sich zur Therapie der erektilen Dysfunktion etabliert und relativiert die Differentialdiagnose zwischen psychogener und organischer Dysfunktion mit den entsprechenden therapeutischen Konsequenzen. Diesem Problem widmet sich diese Studie zur Prüfung der erektilen Antwort unter RigiScan®-Monitoring ohne/mit 50 mg Viagra™. 64 Patienten (mittleres Alter 48 Jahre mit einer erektilen Dysfunktion arteriogener (n = 10, venöser (n = 7, gemischt neurogen/vaskulärer (n = 15 und psychogener (n = 32 Genese von mehr als 6 Monaten Dauer wurden in die Studie aufgenommen. Alle Patienten wurden eingehend diagnostisch abgeklärt, inklusive Hormonlabor, dynamischer Pharmako-Duplexsonographie und, falls indiziert, mit einer Cavernosometrie/ -graphie. Zur Testung der penilen Rigidität und zur Objektivierung der Erektion wurde das "real-time" RigiScan® verwendet. In zwei konsekutiven Messungen wurden sowohl die direkte erektile Antwort auf visuelle Stimulation als auch die nächtlichen Erektionen abgeleitet und die Meßergebnisse mit den Begleiterkrankungen, "lifestyle"-Faktoren und dem Ergebnis der Pharmako-Duplexsonographie korreliert. Es fand sich keine Korrelation zwischen der Ätiologie der erektilen Dysfunktion in bezug auf organische oder psychogene Genese und dem Alter der Patienten, der Dauer der Erektionsstörung, dem Nikotinabusus, den Blutfetten, den Testosteronwerten, dem klinischen Ergebnis der Pharmakotestung (Erektionsgrad und dem duplexsonographisch gemessenen Fluß der penilen Arterien. Hingegen zeigte sich eine positive Korrelation zwischen Genese der erektilen Dysfunktion (organisch bzw. psychogen und dem RigiScan®-Meßergebnis (r = 0,29. Patienten mit psychogen bedingter Erektionsstörung profitierten am meisten von Viagra™, während Patienten mit vaskulärer Genese oder gemischt neurogener/vaskulärer Genese deutlich schlechter auf Viagra™ ansprachen. Es bestand keine Korrelation

A search for stars of very low metal abundance. VI. Detailed abundances of 313 metal-poor stars

International Nuclear Information System (INIS)

Roederer, Ian U.; Preston, George W.; Thompson, Ian B.; Shectman, Stephen A.; Burley, Gregory S.; Kelson, Daniel D.; Sneden, Christopher

2014-01-01

We present radial velocities, equivalent widths, model atmosphere parameters, and abundances or upper limits for 53 species of 48 elements derived from high resolution optical spectroscopy of 313 metal-poor stars. A majority of these stars were selected from the metal-poor candidates of the HK Survey of Beers, Preston, and Shectman. We derive detailed abundances for 61% of these stars for the first time. Spectra were obtained during a 10 yr observing campaign using the Magellan Inamori Kyocera Echelle spectrograph on the Magellan Telescopes at Las Campanas Observatory, the Robert G. Tull Coudé Spectrograph on the Harlan J. Smith Telescope at McDonald Observatory, and the High Resolution Spectrograph on the Hobby-Eberly Telescope at McDonald Observatory. We perform a standard LTE abundance analysis using MARCS model atmospheres, and we apply line-by-line statistical corrections to minimize systematic abundance differences arising when different sets of lines are available for analysis. We identify several abundance correlations with effective temperature. A comparison with previous abundance analyses reveals significant differences in stellar parameters, which we investigate in detail. Our metallicities are, on average, lower by ≈0.25 dex for red giants and ≈0.04 dex for subgiants. Our sample contains 19 stars with [Fe/H] ≤–3.5, 84 stars with [Fe/H] ≤–3.0, and 210 stars with [Fe/H] ≤–2.5. Detailed abundances are presented here or elsewhere for 91% of the 209 stars with [Fe/H] ≤–2.5 as estimated from medium resolution spectroscopy by Beers, Preston, and Shectman. We will discuss the interpretation of these abundances in subsequent papers.

Substitution of peat, fertiliser and manure by compost in hobby gardening: user surveys and case studies.

Science.gov (United States)

Andersen, Jacob K; Christensen, Thomas H; Scheutz, Charlotte

2010-12-01

Four user surveys were performed at recycle centres (RCs) in the Municipalities of Aarhus and Copenhagen, Denmark, to get general information on compost use and to examine the substitution of peat, fertiliser and manure by compost in hobby gardening. The average driving distance between the users' households and the RCs was found to be 4.3 km and the average amount of compost picked up was estimated at 800 kg per compost user per year. The application layer of the compost varied (between 1 and 50 cm) depending on the type of use. The estimated substitution (given as a fraction of the compost users that substitute peat, fertiliser and manure with compost) was 22% for peat, 12% for fertiliser and 7% for manure (41% in total) from the survey in Aarhus (n=74). The estimate from the survey in Copenhagen (n=1832) was 19% for peat, 24% for fertiliser and 15% for manure (58% in total). This is the first time, to the authors' knowledge, that the substitution of peat, fertiliser and manure with compost has been assessed for application in hobby gardening. Six case studies were performed as home visits in addition to the Aarhus surveys. From the user surveys and the case studies it was obvious that the total substitution of peat, fertiliser and manure was not 100%, as is often assumed when assigning environmental credits to compost. It was more likely around 50% and thus there is great potential for improvement. It was indicated that compost was used for a lot of purposes in hobby gardening. Apart from substitution of peat, fertiliser and manure, compost was used to improve soil quality and as a filling material (as a substitute for soil). Benefits from these types of application are, however, difficult to assess and thereby quantify. Copyright © 2010 Elsevier Ltd. All rights reserved.

Mass production of volume phase holographic gratings for the VIRUS spectrograph array

Science.gov (United States)

Chonis, Taylor S.; Frantz, Amy; Hill, Gary J.; Clemens, J. Christopher; Lee, Hanshin; Tuttle, Sarah E.; Adams, Joshua J.; Marshall, J. L.; DePoy, D. L.; Prochaska, Travis

2014-07-01

The Visible Integral-field Replicable Unit Spectrograph (VIRUS) is a baseline array of 150 copies of a simple, fiber-fed integral field spectrograph that will be deployed on the Hobby-Eberly Telescope (HET). VIRUS is the first optical astronomical instrument to be replicated on an industrial scale, and represents a relatively inexpensive solution for carrying out large-area spectroscopic surveys, such as the HET Dark Energy Experiment (HETDEX). Each spectrograph contains a volume phase holographic (VPH) grating with a 138 mm diameter clear aperture as its dispersing element. The instrument utilizes the grating in first-order for 350 VPH gratings has been mass produced for VIRUS. Here, we present the design of the VIRUS VPH gratings and a discussion of their mass production. We additionally present the design and functionality of a custom apparatus that has been used to rapidly test the first-order diffraction efficiency of the gratings for various discrete wavelengths within the VIRUS spectral range. This device has been used to perform both in-situ tests to monitor the effects of adjustments to the production prescription as well as to carry out the final acceptance tests of the gratings' diffraction efficiency. Finally, we present the as-built performance results for the entire suite of VPH gratings.

BD+15 2940 AND HD 233604: TWO GIANTS WITH PLANETS CLOSE TO THE ENGULFMENT ZONE

International Nuclear Information System (INIS)

Nowak, G.; Niedzielski, A.; Adamów, M.; Maciejewski, G.; Wolszczan, A.

2013-01-01

We report the discovery of planetary-mass companions to two red giants by the ongoing Penn State-Toruń Planet Search (PTPS) conducted with the 9.2 m Hobby-Eberly Telescope. The 1.1 M ☉ K0-giant, BD+15 2940, has a 1.1 M J minimum mass companion orbiting the star at a 137.5 day period in a 0.54 AU orbit what makes it the closest—in planet around a giant and possible subject of engulfment as the consequence of stellar evolution. HD 233604, a 1.5 M ☉ K5-giant, is orbited by a 6.6 M J minimum mass planet which has a period of 192 days and a semi-major axis of only 0.75 AU making it one of the least distant planets to a giant star. The chemical composition analysis of HD 233604 reveals a relatively high 7 Li abundance which may be a sign of its early evolutionary stage or recent engulfment of another planet in the system. We also present independent detections of planetary-mass companions to HD 209458 and HD 88133, and stellar activity-induced radial velocity variations in HD 166435, as part of the discussion of the observing and data analysis methods used in the PTPS project.

Wirksamkeit und Sicherheit von Fumarsäureestern in Kombination mit Phototherapie bei Patienten mit moderater bis schwerer Plaque-Psoriasis (FAST).

Science.gov (United States)

Weisenseel, Peter; Reich, Kristian; Griemberg, Wiebke; Merten, Katharina; Gröschel, Christine; Gomez, Natalie Nunez; Taipale, Kirsi; Bräu, Beate; Zschocke, Ina

2017-02-01

Die Behandlung von Psoriasis-Patienten mit einer Kombination aus Fumarsäureestern (FSE, Fumaderm ® ) und Phototherapie (UV) ist verbreitet, wurde aber im Rahmen von Studien wenig untersucht. Bisher liegen lediglich Daten aus einer kleinen Pilotstudie vor. Intention dieser Studie war, eine FSE/UV-Kombinationsbehandlung an einem größeren Patientenkollektiv mit mittelschwerer bis schwerer Psoriasis zu untersuchen. In dieser prospektiven, multizentrischen, nichtinterventionellen Studie wurden Daten von Patienten mit FSE/UV-Kombinationstherapie hinsichtlich der Wirksamkeit (PGA' PASI, DLQI, EQ-5D), Sicherheit und Dosierung über einen Zeitraum von zwölf Monaten erfasst und mit Daten einer retrospektiven Studie mit FSE-Monotherapie verglichen. Es wurden Daten von 363 Patienten ausgewertet. Unter der Kombinationstherapie verbesserten sich alle Wirksamkeitsparameter deutlich. Im Vergleich zur Monotherapie mit FSE konnte durch die Kombination mit UV ein schnellerer Wirkeintritt erzielt werden, wobei nach zwölf Monaten kein Unterschied in der Wirksamkeit bestand. Die Dauer und Art der Phototherapie zeigte keinen Einfluss auf die Wirksamkeitsparameter. Allgemein wurde die Kombinationstherapie gut vertragen. Unerwünschte Ereignisse wurden bei 7 % der Patienten berichtet. Die FSE/UV Kombinationstherapie zeigt eine gute Wirksamkeit und Verträglichkeit und kann zu einem schnelleren Wirkeintritt führen. Eine Kombinationstherapie erscheint vor allem in den ersten drei Monaten der FSE Behandlung sinnvoll. © 2017 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

MACH MIT: Deutsches Wochenende am Karlsfluss (MACH MIT: a German Week-End on the Charles River).

Science.gov (United States)

Reizes, Sonia; Kramsch, Claire J.

1980-01-01

Describes a joint high school/college pilot program planned by Massachusetts foreign language teachers and hosted by M.I.T. The success of the program dubbed "MACH MIT Total Immersion German Weekend" is attributed to the concept of active involvement, which was implemented through games, seminars, shows, cooking and other activities.…

Texas-style Fundraising and Public Relations for the International Year of Astronomy

Science.gov (United States)

Preston, Sandra; Barna, J. W.; Geiger, S.; Johnson, R.; Rimm, N.; Griffin, J.; Watson, K.

2008-05-01

McDonald Observatory can be a leader in Texas for the International Year of Astronomy (IYA09) celebration. Our strategy builds on the IYA09 program, tailoring it for the Texas audience, while also nationally promoting McDonald Observatory, UT Astronomy, the Hobby-Eberly Telescope Dark Energy Experiment (HETDEX) and our partnership in the Giant Magellan Telescope (GMT). We will also use this opportunity to make a concentrated outreach effort toward the Hispanic and Spanish-speaking communities in Texas and the nation, aligning with the IYA09 objective for improving relations with underrepresented and minority populations. Fundraising is a key ingredient to our success in 2009 and the future. With NASA Office of Space Science funding for education and public outreach being rethought, we will be focusing on new sources for fundraising, including private donations and corporate sponsorship, augmented by planned giving. We will take advantage of the timing to raise funds for special IYA09 programs, as well as for our large telescope projects HETDEX and GMT, along with our endowment and planned giving programs for education, outreach, and research. We will work with the UT McCombs School of Business on corporate sponsorship. During this time we will also go through a branding experience that will visually unify McDonald Observatory, UT Astronomy, and the education and public outreach programs. A consistent brand that can be used on the website and other media is our goal to build a stronger public presence that will aid us in our fundraising efforts. A Public Relations Internship Project produced a report to help launch this process. We are working with the UT College of Communications Advertising Department and with Hill Strategic Brand Solutions in Houston, Texas. We hope that our efforts will produce Texas-sized results!

MITS machine operations

International Nuclear Information System (INIS)

Flinchem, J.

1980-01-01

This document contains procedures which apply to operations performed on individual P-1c machines in the Machine Interface Test System (MITS) at AiResearch Manufacturing Company's Torrance, California Facility

Tracking Advanced Planetary Systems (TAPAS) with HARPS-N. V. A Massive Jupiter orbiting the very-low-metallicity giant star BD+03 2562 and a possible planet around HD 103485

Science.gov (United States)

Villaver, E.; Niedzielski, A.; Wolszczan, A.; Nowak, G.; Kowalik, K.; Adamów, M.; Maciejewski, G.; Deka-Szymankiewicz, B.; Maldonado, J.

2017-10-01

Context. Evolved stars with planets are crucial to understanding the dependency of the planet formation mechanism on the mass and metallicity of the parent star and to studying star-planet interactions. Aims: We present two evolved stars (HD 103485 and BD+03 2562) from the Tracking Advanced PlAnetary Systems (TAPAS) with HARPS-N project devoted to RV precision measurements of identified candidates within the PennState - Toruń Centre for Astronomy Planet Search. Methods: The paper is based on precise radial velocity (RV) measurements. For HD 103485 we collected 57 epochs over 3317 days with the Hobby-Eberly Telescope (HET) and its high-resolution spectrograph and 18 ultra-precise HARPS-N data over 919 days. For BD+03 2562 we collected 46 epochs of HET data over 3380 days and 19 epochs of HARPS-N data over 919 days. Results: We present the analysis of the data and the search for correlations between the RV signal and stellar activity, stellar rotation, and photometric variability. Based on the available data, we interpret the RV variations measured in both stars as Keplerian motion. Both stars have masses close to Solar (1.11 M⊙ HD 103485 and 1.14 M⊙ BD+03 2562), very low metallicities ([Fe/H] = - 0.50 and - 0.71 for HD 103485 and BD+03 2562), and both have Jupiter planetary mass companions (m2sini = 7 and 6.4 MJ for HD 103485 and BD+03 2562 resp.) in close to terrestrial orbits (1.4 au HD 103485 and 1.3 au BD+03 2562) with moderate eccentricities (e = 0.34 and 0.2 for HD 103485 and BD+03 2562). However, we cannot totally rule-out the possibility that the signal in the case of HD 103485 is due to rotational modulation of active regions. Conclusions: Based on the current data, we conclude that BD+03 2562 has a bona fide planetary companion while for HD 103485 we cannot totally exclude the possibility that the best explanation for the RV signal modulations is not the existence of a planet but stellar activity. If the interpretation remains that both stars have

Editorial 3/2015: Handeln mit Symbolen

Directory of Open Access Journals (Sweden)

Alessandro Barberi

2015-09-01

Full Text Available Die paradigmatische Unterscheidung zwischen Sozial- und Kulturwissenschaften, die spätestens seit den 1980er Jahren eingehend diskutiert wurde, lässt sich anhand des Bereichs des Symbolischen auf den Punkt bringen: Ist das Symbolische nur ein Effekt von sozialen, ökonomischen oder medialen Strukturen einer gegebenen Gesellschaft oder reproduzieren sich Strukturen nur durch die symbolischen Handlungen der AkteurInnen innerhalb einer gegebenen Kultur? So hatte etwa der klassische "harte" Strukturalismus bei Claude Lévi-Strauss, Jacques Lacan und dem frühen Michel Foucault symbolische Ordnungen (und d. i. hier die Sprache als eine unbewusst determinierende Voraussetzung von menschlicher Interaktion begriffen, woraufhin mit dem Post- bzw. Neostrukturalismus die Rückkehr der individuellen Äußerung, der parole, des speech acts (und d. i. hier das Sprechen, also der symbolischen Handlung in den Mittelpunkt rückte. Medienpädagogisch ist diese Unterscheidung gerade dann von Interesse, wenn es darum geht, wie Lehrende und Lernende sich zueinander verhalten, interagieren und dabei eben mit Symbolen handeln. Insofern ist es bemerkenswert, dass – fast parallel zu Foucaults Unterscheidung von diskursiven und nicht-diskursiven Praktiken – auch Dieter Baacke 1973 von diskursiven und nicht-diskursiven Symbolen gesprochen hat. Denn – wie auch im Rahmen des "Symbolischen Interaktionismus" von George Herbert Mead argumentiert wurde – können Symbole nur im Rahmen einer gegebenen Diskursökonomie von AkteurInnen diskursiv ausgetauscht werden und konstituieren dabei Erfahrungen bzw. Wahrnehmungen und somit auch die soziale bzw. kulturelle Wirklichkeit. Insofern ist die Frage nach dem Symbolischen immer auch eine Frage nach den Möglichkeiten der Handlungstheorie (im Sinne Jürgen Habermas’ bzw. der Praxeologie (im Sinne Pierre Bourdieus. Die Redaktion der MEDIENIMPULSE geht in diesem Zusammenhang theoretisch und praktisch von Entscheidungsimpulse

Mit kokkeri

DEFF Research Database (Denmark)

Ejlersen, Søren; Lorang, Louisa

MIT kokkeri er resultatet af et samarbejde mellem Komiteen for Sundhedsoplysning, Institut for Uddannelse og Pædagogik/Aarhus Universitet og Haver til Maver. Projektet støttes af Nordea-fonden. Bag kogebogens mange opskrifter står en række erfarne madeksperter bestående af Søren Ejlersen, Louisa...

Advanced X-Ray Telescope Mirrors Provide Sharpest Focus Ever

Science.gov (United States)

1997-03-01

for the Office of Space Science, NASA Headquarters, Washington, DC. Using glass purchased from Schott Glaswerke, Mainz, Germany, the telescope's mirrors were built by Hughes Danbury Optical Systems, Danbury, CT. The mirrors were coated by Optical Coating Laboratory, Inc., Santa Rosa, CA; and assembled by Eastman-Kodak Company, Rochester, NY. The AXAF CCD Imaging Spectrometer instrument was developed by Pennsylvania State University, University Park, and the Massachusetts Institute of Technology (MIT), Cambridge, MA. One of the two gratings was developed by MIT. The other was developed by the Space Research Organization Netherlands, Utrecht, Netherlands, in collaboration with the Max Planck Institute, Garching, Germany. The High Resolution Camera instrument was built by the Smithsonian Astrophysical Observatory. Note to editors: Digital images to accompany this release are available via the World Wide Web at the following URL: http://chandra.harvard.edu/press/images.html A photograph is available from the NASA Headquarters Audio Imaging Branch to news media to illustrate this story. The Photograph number is 97-HC-138. Photographs also are available from the Marshall Public Affairs office at 205/544-0034.

Kompressionstherapie bei Patienten mit Ulcus cruris venosum.

Science.gov (United States)

Dissemond, Joachim; Assenheimer, Bernd; Bültemann, Anke; Gerber, Veronika; Gretener, Silvia; Kohler-von Siebenthal, Elisabeth; Koller, Sonja; Kröger, Knut; Kurz, Peter; Läuchli, Severin; Münter, Christian; Panfil, Eva-Maria; Probst, Sebastian; Protz, Kerstin; Riepe, Gunnar; Strohal, Robert; Traber, Jürg; Partsch, Hugo

2016-11-01

Wund-D.A.CH. ist der Dachverband deutschsprachiger Fachgesellschaften, die sich mit den Thematiken der Wundbehandlung beschäftigen. Experten verschiedener Fachgesellschaften aus Deutschland, Österreich und der Schweiz haben nun einen aktuellen Konsens der Kompressionstherapie für Patienten mit Ulcus cruris venosum erstellt. In Europa ist das Ulcus cruris venosum eine der häufigsten Ursachen für chronische Wunden. Neben der konservativen und interventionellen Wund- und Venentherapie, ist die Kompressionstherapie die Basis der Behandlungsstrategien. Die Kompressionstherapie kann heute mit sehr unterschiedlichen Materialien und Systemen durchgeführt werden. Während in der Entstauungsphase insbesondere Verbände mit Kurzzugbinden oder Mehrkomponentensysteme zur Anwendung kommen, sind es anschließend überwiegend Ulkus-Strumpfsysteme. Eine weitere, bislang wenig verbreitete Alternative sind adaptive Kompressionsbandagen. Insbesondere für die Rezidivprophylaxe werden medizinische Kompressionsstrümpfe empfohlen. Durch die Vielzahl der heute zur Verfügung stehenden Behandlungsoptionen, kann für nahezu alle Patienten ein Konzept entwickelt werden, dass sich an den individuellen Bedürfnissen und Fähigkeiten orientiert und daher auch akzeptiert und durchgeführt wird. Die Kompressionstherapie ist für die Behandlung von Patienten mit Ulcus cruris venosum essentiell. In den letzten Jahren sind viele verschiedene Therapieoptionen verfügbar, die in den deutschsprachigen Ländern unterschiedlich angewendet oder durchgeführt werden. Daher soll dieser Expertenkonsens dazu beitragen, konkrete Empfehlungen für die praktische Durchführung der Kompressionstherapie von Patienten mit Ulcus cruris venosum darzustellen. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

Minimally invasive thyroidectomy (MIT): indications and results.

Science.gov (United States)

Docimo, Giovanni; Salvatore Tolone, Salvatore; Gili, Simona; d'Alessandro, A; Casalino, G; Brusciano, L; Ruggiero, Roberto; Docimo, Ludovico

2013-01-01

To establish if the indication for different approaches for thyroidectomy and the incision length provided by means of pre-operative assessment of gland volume and size of nodules resulted in safe and effective outcomes and in any notable aesthetic or quality-of-life impact on patients. Ninehundred eightytwo consecutive patients, undergoing total thyroidectomy, were enrolled. The thyroid volume and maximal nodule diameter were measured by means of ultrasounds. Based on ultrasounds findings, patients were divided into three groups: minimally invasive video assisted thyroidectomy (MIVAT), minimally invasive thyroidectomy (MIT) and conventional thyroidectomy (CT) groups. The data concerning the following parameters were collected: operative time, postoperative complications, postoperative pain and cosmetic results. The MIVAT group included 179 patients, MIT group included 592 patients and CT group included 211 patients. Incidence of complications did not differ significantly in each group. In MIVAT and MIT group, the perception of postoperative pain was less intense than CT group. The patients in the MIVAT (7±1.5) and MIT (8±2) groups were more satisfied with the cosmetic results than those in CT group (5±1.3) (p= MIT is a technique totally reproducible, and easily convertible to perform surgical procedures in respect of the patient, without additional complications, increased costs, and with better aesthetic results.

Wrestling with Pedagogical Change: The TEAL Initiative at MIT

Science.gov (United States)

Breslow, Lori

2010-01-01

In the late 1990s, the physics department at the Massachusetts Institute of Technology (MIT) had a problem. The department was responsible for teaching the two required physics courses that are part of the General Institute Requirements (GIRs), MIT's core curriculum--Physics I (mechanics, or in MIT parlance, 8.01) and Physics II (electricity and…

Untersuchungen an Eisen- und Lanthanoidhaltigen Koordinationsclustern mit Triazolat- sowie Semiquinonato-Liganden

OpenAIRE

Kriese, Thomas

2016-01-01

Magnetische Untersuchungen an Lanthanoiddimeren mit Semiquinonato-Liganden. Gemischtvalente Eisen-Koordinationsclustern. Lanthanoid-Koordinationscluster mit zwölf Lanthanoiden aber mit verschiedenen Clusterladungen.

Chronisch-dekompensierter Tinnitus: ein heterogenes Krankheitsbild mit Auswirkungen auf den Behandlungserfolg

OpenAIRE

Ivansic, D; Müller, B; Dobel, C; Guntinas-Lichius, O

2017-01-01

Einleitung: Bei etwa 5% der Patienten mit chronischem Tinnitus gehen die Ohrgeräusche mit erheblichem Leidensdruck, häufig auch mit psychiatrischen Störung einher. Da es aktuell keine wirksame Behandlung gibt, welche zu Beseitigung des chronischen Tinnitus führt, ist das Therapieziel die Reduktion der Tinnitus-Belastung. Methodik: Es wurden von 7/13 bis 12/14 308 Patienten mit chronischen Tinnitus tagesklinisch interdisziplinär behandelt. Die Tinnitus-Belastung wurde mit Tinnitus-Fragebogen...

Theoretical results on the tandem junction solar cell based on its Ebers-Moll transistor model

Science.gov (United States)

Goradia, C.; Vaughn, J.; Baraona, C. R.

1980-01-01

A one-dimensional theoretical model of the tandem junction solar cell (TJC) with base resistivity greater than about 1 ohm-cm and under low level injection has been derived. This model extends a previously published conceptual model which treats the TJC as an npn transistor. The model gives theoretical expressions for each of the Ebers-Moll type currents of the illuminated TJC and allows for the calculation of the spectral response, I(sc), V(oc), FF and eta under variation of one or more of the geometrical and material parameters and 1MeV electron fluence. Results of computer calculations based on this model are presented and discussed. These results indicate that for space applications, both a high beginning of life efficiency, greater than 15% AM0, and a high radiation tolerance can be achieved only with thin (less than 50 microns) TJC's with high base resistivity (greater than 10 ohm-cm).

Structure and Formation of cD Galaxies: NGC 6166 in ABELL 2199

Science.gov (United States)

Bender, Ralf; Kormendy, John; Cornell, Mark E.; Fisher, David B.

2015-07-01

 Hobby-Eberly Telescope (HET) spectroscopy is used to measure the velocity dispersion profile of the nearest prototypical cD galaxy, NGC 6166 in the cluster Abell 2199. We also present composite surface photometry from many telescopes. We confirm the defining feature of a cD galaxy; i.e., (we suggest), a halo of stars that fills the cluster center and that is controlled dynamically by cluster gravity, not by the central galaxy. Our HET spectroscopy shows that the velocity dispersion of NGC 6166 rises from σ ≃ 300 km s-1 in the inner r˜ 10\\prime\\prime to σ =865+/- 58 km s-1 at r ˜ 100″ in the cD halo. This extends published observations of an outward σ increase and shows for the first time that σ rises all the way to the cluster velocity dispersion of 819 ± 32 km s-1. We also observe that the main body of NGC 6166 moves at +206 ± 39 km s-1 with respect to the cluster mean velocity, but the velocity of the inner cD halo is ˜70 km s-1 closer to the cluster velocity. These results support our picture that cD halos consist of stars that were stripped from individual cluster galaxies by fast tidal encounters.  However, our photometry does not confirm the widespread view that cD halos are identifiable as an extra, low-surface-brightness component that is photometrically distinct from the inner, steep-Sérsic-function main body of an otherwise-normal giant elliptical galaxy. Instead, all of the brightness profile of NGC 6166 outside its core is described to ±0.037 V mag arcsec-2 by a single Sérsic function with index n≃ 8.3. The cD halo is not recognizable from photometry alone. This blurs the distinction between cluster-dominated cD halos and the similarly-large-Sérsic-index halos of giant, core-boxy-nonrotating ellipticals. These halos are believed to be accreted onto compact, high-redshift progenitors (“red nuggets”) by large numbers of minor mergers. They belong dynamically to their central galaxies. Still, cDs and core-boxy-nonrotating Es

Hamlet er manden i mit liv

DEFF Research Database (Denmark)

Rösing, Lilian Munk

2009-01-01

Hamlet er manden i mit liv. Min elskede. Jeg har en drøm om at frelse ham. At redde ham ud af sin mors soveværelse og ind i mit. Væk fra det ødipale Helvede han befinder sig i, fastlåst mellem et svin af en faderskikkelse (Claudius) og en alt for idealiseret far (gamle Hamlet), vågende over sin m...

EBER - development of evaluation methods for shipping and storage containers with an increased content of metallic residual materials

International Nuclear Information System (INIS)

Droste, B.; Voelzke, H.

1995-01-01

Containers which are manufactured using recycled metallic residual materials from decommissioned nuclear facilities must be designed in accordance with the requirements of transport, interim and ultimate storage of radioactive waste. When metallic residual materials are added to the melt in the manufacture of containers made of cast iron with nodular graphite (GGG 40), how the effect on and characteristics of materials are to be observed as well as the permissible limits. The influence on charcteristics of relevance to safety, such as fracture toughness and the types and magnitudes of defects in construction components are the most important factors. In BAM's 'EBER' project presented here, the studies concentrate on design-based safety against the mechanical effects of accidents. (orig./DG) [de

Redoxspeziation von endlagerrelevanten Elementen mit Hilfe von Trennmethoden gekoppelt an ein Massenspektrometer mit induktiv gekoppeltem Plasma

OpenAIRE

Graser, Carl-Heinrich

2015-01-01

Im Rahmen dieser Arbeit wurden Redoxspeziationsanalysen von Eisen, Neptunium und Plutonium per CE-SF-ICP-MS durchgeführt. Durch Optimierung der Trennparameter konnten Trennungen der Pu Oxidationsstufen III bis VI und Trennungen der Np Oxidationsstufen IV bis VI binnen 15 Minuten mit einer Nachweisgrenze von 10-12 M durchgeführt werden. Die Trennung der Fe Oxidationsstufen II und III gelang in weniger als 5 Minuten mit einer Nachweisgrenze von 5-10-8 M.

Biotechnology Process Engineering Center at MIT Home

Science.gov (United States)

has provided a focal point for biotechnology research and education at MIT. Prominent examples include the NIH Training Program in Biotechnology and the NIH Training Program in Genomics; both of these are -genomic biology. Another example is the new DuPont-MIT Alliance (DMA), focused on materials biotechnology

Relationship of Having Hobbies and a Purpose in Life With Mortality, Activities of Daily Living, and Instrumental Activities of Daily Living Among Community-Dwelling Elderly Adults.

Science.gov (United States)

Tomioka, Kimiko; Kurumatani, Norio; Hosoi, Hiroshi

2016-07-05

This study's aim was to clarify the relationship of having hobbies and a purpose in life (PIL; in Japanese, ikigai) with mortality and a decline in the activities of daily living (ADL) and instrumental ADL (IADL) among the community-dwelling elderly. Prospective observational data from residents aged ≥65 years who were at increased risk for death (n = 1853) and developing a decline in ADL (n = 1254) and IADL (n = 1162) were analyzed. Cox proportional hazard models were used for mortality analysis of data from February 2011 to November 2014. ADL and IADL were evaluated using the Barthel Index and the Tokyo Metropolitan Institute of Gerontology Index of Competence, respectively. ADL and IADL were assessed at baseline and follow-up and were evaluated using logistic regression models. Fully adjusted models included terms for age, gender, BMI, income, alcohol intake, smoking history, number of chronic diseases, cognitive function, and depression. During the follow-up of eligible participants, 248 had died, 119 saw a decline in ADL, and 178 saw a decline in IADL. In fully adjusted models, having neither hobbies nor PIL was significantly associated with an increased risk of mortality (hazard ratio 2.08; 95% confidence interval [CI], 1.47-2.94), decline in ADL (odds ratio 2.74; 95% CI, 1.44-5.21), and decline in IADL (odds ratio 1.89; 95% CI, 1.01-3.55) compared to having both hobbies and PIL. Although effect modifications by cognitive functioning and depression cannot be ruled out, our findings suggest that having hobbies and PIL may extend not only longevity, but also healthy life expectancy among community-dwelling older adults.

Perancangan Sistem Pendukung Keputusan Seleksi Penerimaan Karyawan Dengan Metode Simple Additive Weighting (SAW (Studi Kasus Toko Markas Hobby

Directory of Open Access Journals (Sweden)

Dadi Rosadi

2017-06-01

Full Text Available Selection process for new employees at the Markas Hobby is still done manually, the application file new candidates will be evaluated by comparing the file contents with the specified criteria. Selection of the files that meet the criteria then continued with the interview process. The series of processes followed by a series written the tests, including psychological tests, tests of academic potential and so on. Statements this thesis aims to build a Decision Support System Selection Recruitment of new uses Simple Additive weighting method (SAW. This method was chosen because it can determine the weight values for each attribute, and then proceed with the ranking process that will select the best alternative from several alternatives, In this case, the alternative is entitled to be accepted as a new employee in accordance with criteria specified. In developing this application writer use the method of RUP (Rational Unified Process, with Descriptive Research Methodology and Action Research Methodology. While the system implementation using PHP programming language and MySQL as the database. The decision support system may help section Recruitment in making decisions for the recruitment process at Markas Hobby more easily and quickly.

Grosse Axiallager mit Hybridschmierung - Theoretische und experimentelle Betrachtungen

DEFF Research Database (Denmark)

Santos, Ilmar; Fuerst, Axel

2003-01-01

Der vorliegende Artikel praesentiert die Simulation eines grossen axialen Kippsegmentlagers unter Beruecksichtigung der hybriden Schmierung, d.h. gleichzeitige hydrodynamische und hydrostatische Schmierung. Ein Vergleich mit Messungen zeigt, dass fuer das betrachtete Lager mit 2,2 m Durchmesser die...

Interstellar Lithium and Rubidium in the Diffuse Gas Near IC 443

Science.gov (United States)

Ritchey, Adam M.; Taylor, C. J.; Federman, S. R.; Lambert, D. L.

2011-01-01

We present an analysis of interstellar lithium and rubidium from observations made with the Hobby-Eberly Telescope at McDonald Observatory of the Li I λ6707 and Rb I λ7800 absorption lines along four lines of sight through the supernova remnant IC 443. The observations probe interstellar material polluted by the ejecta of a core-collapse (Type II) supernova and can thus be used to constrain the contribution from massive stars to the synthesis of lithium and rubidium. Production of 7Li is expected to occur through neutrino spallation in the helium and carbon shells of the progenitor star during the terminal supernova explosion, while both 6Li and 7Li are synthesized via spallation and fusion reactions involving cosmic rays accelerated by the remnant. Gamma-ray emission from IC 443 provides strong evidence for the interaction of accelerated cosmic rays with the ambient atomic and molecular gas. Rubidium is also produced by massive stars through the weak s-process in the He- and C-burning shells and the r-process during core collapse. We examine interstellar 7Li/6Li isotope ratios as well as Li/K and Rb/K ratios along each line of sight, and discuss the implications of our results in the context of nucleosynthesis associated with Type II supernovae.

PLANETARY NEBULAE IN FACE-ON SPIRAL GALAXIES. II. PLANETARY NEBULA SPECTROSCOPY

International Nuclear Information System (INIS)

Herrmann, Kimberly A.; Ciardullo, Robin

2009-01-01

As the second step in our investigation of the mass-to-light ratio of spiral disks, we present the results of a spectroscopic survey of planetary nebulae (PNe) in five nearby, low-inclination galaxies: IC 342, M74 (NGC 628), M83 (NGC 5236), M94 (NGC 4736), and M101 (NGC 5457). Using 50 setups of the WIYN/Hydra and Blanco/Hydra spectrographs, and 25 observations with the Hobby-Eberly Telescope's Medium Resolution Spectrograph, we determine the radial velocities of 99, 102, 162, 127, and 48 PNe, respectively, to a precision better than 15 km s -1 . Although the main purpose of this data set is to facilitate dynamical mass measurements throughout the inner and outer disks of large spiral galaxies, our spectroscopy has other uses as well. Here, we co-add these spectra to show that, to first order, the [O III] and Balmer line ratios of PNe vary little over the top ∼1.5 mag of the PN luminosity function. The only obvious spectral change occurs with [N II], which increases in strength as one proceeds down the luminosity function. We also show that typical [O III]-bright planetaries have E(B - V) ∼ 0.2 of circumstellar extinction, and that this value is virtually independent of [O III] luminosity. We discuss the implications this has for understanding the population of PN progenitors.

THE HETDEX PILOT SURVEY. I. SURVEY DESIGN, PERFORMANCE, AND CATALOG OF EMISSION-LINE GALAXIES

International Nuclear Information System (INIS)

Adams, Joshua J.; Blanc, Guillermo A.; Gebhardt, Karl; Hao, Lei; Byun, Joyce; Fry, Alex; Jeong, Donghui; Komatsu, Eiichiro; Hill, Gary J.; Cornell, Mark E.; MacQueen, Phillip J.; Drory, Niv; Bender, Ralf; Hopp, Ulrich; Kelzenberg, Ralf; Ciardullo, Robin; Gronwall, Caryl; Finkelstein, Steven L.; Gawiser, Eric; Kelz, Andreas

2011-01-01

We present a catalog of emission-line galaxies selected solely by their emission-line fluxes using a wide-field integral field spectrograph. This work is partially motivated as a pilot survey for the upcoming Hobby-Eberly Telescope Dark Energy Experiment. We describe the observations, reductions, detections, redshift classifications, line fluxes, and counterpart information for 397 emission-line galaxies detected over 169 □' with a 3500-5800 A bandpass under 5 A full-width-half-maximum (FWHM) spectral resolution. The survey's best sensitivity for unresolved objects under photometric conditions is between 4 and 20x 10 -17 erg s -1 cm -2 depending on the wavelength, and Lyα luminosities between 3 x 10 42 and 6 x 10 42 erg s -1 are detectable. This survey method complements narrowband and color-selection techniques in the search of high-redshift galaxies with its different selection properties and large volume probed. The four survey fields within the COSMOS, GOODS-N, MUNICS, and XMM-LSS areas are rich with existing, complementary data. We find 105 galaxies via their high-redshift Lyα emission at 1.9 44 □' which appear to be extended Lyα nebulae. We also find three high-z objects with rest-frame Lyα EW above the level believed to be achievable with normal star formation, EW 0 >240 A. Future papers will investigate the physical properties of this sample.

KINEMATIC SIGNATURES OF BULGES CORRELATE WITH BULGE MORPHOLOGIES AND SÉRSIC INDEX

International Nuclear Information System (INIS)

Fabricius, Maximilian H.; Saglia, Roberto P.; Bender, Ralf; Hopp, Ulrich; Fisher, David B.; Drory, Niv

2012-01-01

We use the Marcario Low Resolution Spectrograph at the Hobby-Eberly Telescope to study the kinematics of pseudobulges and classical bulges in the nearby universe. We present major axis rotational velocities, velocity dispersions, and h 3 and h 4 moments derived from high-resolution (σ inst ≈ 39 km s –1 ) spectra for 45 S0 to Sc galaxies; for 27 of the galaxies we also present minor axis data. We combine our kinematics with bulge-to-disk decompositions. We demonstrate for the first time that purely kinematic diagnostics of the bulge dichotomy agree systematically with those based on Sérsic index. Low Sérsic index bulges have both increased rotational support (higher v/σ values) and on average lower central velocity dispersions. Furthermore, we confirm that the same correlation also holds when visual morphologies are used to diagnose bulge type. The previously noted trend of photometrically flattened bulges to have shallower velocity dispersion profiles turns out to be significant and systematic if the Sérsic index is used to distinguish between pseudobulges and classical bulges. The anti-correlation between h 3 and v/σ observed in elliptical galaxies is also observed in intermediate-type galaxies, irrespective of bulge type. Finally, we present evidence for formerly undetected counter-rotation in the two systems NGC 3945 and NGC 4736.

Parsec-scale Variations in the 7Li I/6Li I Isotope Ratio Toward IC 348 and the Perseus OB 2 Association

Science.gov (United States)

Knauth, D. C.; Taylor, C. J.; Ritchey, A. M.; Federman, S. R.; Lambert, D. L.

2017-01-01

Measurements of the lithium isotopic ratio in the diffuse interstellar medium from high-resolution spectra of the Li I λ6708 resonance doublet have now been reported for a number of lines of sight. The majority of the results for the 7Li/6Li ratio are similar to the solar system ratio of 12.2, but the line of sight toward o Per, a star near the star-forming region IC 348, gave a ratio of about two, the expected value for gas exposed to spallation and fusion reactions driven by cosmic rays. To examine the association of IC 348 with cosmic rays more closely, we measured the lithium isotopic ratio for lines of sight to three stars within a few parsecs of o Per. One star, HD 281159, has 7Li/6Li ≃ 2 confirming production by cosmic rays. The lithium isotopic ratio toward o Per and HD 281159 together with published analyses of the chemistry of interstellar diatomic molecules suggest that the superbubble surrounding IC 348 is the source of the cosmic rays. Based on observations obtained with the Hobby-Eberly Telescope, which is a joint project of the University of Texas at Austin, the Pennsylvania State University, Ludwig-Maximilians-Universität München, and Georg-August-Universität Göttingen.

Mit anderen Augen

DEFF Research Database (Denmark)

Ydesen, Christian; Høberg, Per

2010-01-01

The article 'Mit anderen Augen' focuses on the debate about the state-church relationship in the German Democratic Republic (GDR). Starting from the immediate assumption that a protestant church and a socialist, Marxist-Leninist state were irreconcilable in the construction of a new society...

MIT-Skywalker: On the use of a markerless system.

Science.gov (United States)

Goncalves, Rogerio S; Hamilton, Taya; Krebs, Hermano I

2017-07-01

This paper describes our efforts to employ the Microsoft Kinect as a low cost vision control system for the MIT-Skywalker, a robotic gait rehabilitation device. The Kinect enables an alternative markerless solution to control the MIT-Skywalker and allows a more user-friendly set-up. A study involving eight healthy subjects and two stroke survivors using the MIT-Skywalker device demonstrates the advantages and challenges of this new proposed approach.

Assembly of NASA's Most Powerful X-Ray Telescope Completed

Science.gov (United States)

1998-03-01

holes, many of which are invisible to us now. We may even see the processes that create the elements found here on Earth." Assembly of the observatory began in 1997 with the arrival of the high resolution mirror assembly at TRW Space and Electronics Group. In August 1997, the telescope's optical bench was mated with the mirrors, followed by integration of the telescope with the spacecraft in October. In February 1998, the observatory's science instrument module was mated to the top of the telescope. The complete observatory is 45 feet long, has a solar array wing span 64 feet wide, and weighs more than 5 tons. Using glass purchased from Schott Glaswerke, Mainz, Germany, the telescope's mirrors were built by Raytheon Optical Systems Inc., Danbury, Conn. The mirrors were coated by Optical Coating Laboratory Inc., Santa Rosa, Calif.; and assembled by Eastman-Kodak Co., Rochester, N.Y. The observatory's charged coupled device imaging spectrometer was developed by Pennsylvania State University at University Park, and the Massachusetts Institute of Technology (MIT), at Cambridge. One diffraction grating was developed by MIT, the other by the Space Research Organization Netherlands, Utrecht, in collaboration with the Max Planck Institute, Garching, Germany. The high resolution camera instrument was built by the Smithsonian Astrophysical Observatory. Ball Aerospace & Technologies Corporation of Boulder, Colo., developed the science instrument module. The Advanced X-ray Astrophysics Facility program is managed by the Marshall Center for the Office of Space Science, NASA Headquarters, Washington, D.C. The Smithsonian Astrophysical Observatory in Cambridge, Mass., will operate the observatory for NASA. NOTE TO EDITORS: A photo of the integrated telescope is available via the World Wide Web at URL: http://chandra.harvard.edu/press/images.html Prepared by John Bryk

Relationship of Having Hobbies and a Purpose in Life With Mortality, Activities of Daily Living, and Instrumental Activities of Daily Living Among Community-Dwelling Elderly Adults

Directory of Open Access Journals (Sweden)

Kimiko Tomioka

2016-07-01

Full Text Available Background: This study’s aim was to clarify the relationship of having hobbies and a purpose in life (PIL; in Japanese, ikigai with mortality and a decline in the activities of daily living (ADL and instrumental ADL (IADL among the community-dwelling elderly. Methods: Prospective observational data from residents aged ≥65 years who were at increased risk for death (n = 1853 and developing a decline in ADL (n = 1254 and IADL (n = 1162 were analyzed. Cox proportional hazard models were used for mortality analysis of data from February 2011 to November 2014. ADL and IADL were evaluated using the Barthel Index and the Tokyo Metropolitan Institute of Gerontology Index of Competence, respectively. ADL and IADL were assessed at baseline and follow-up and were evaluated using logistic regression models. Fully adjusted models included terms for age, gender, BMI, income, alcohol intake, smoking history, number of chronic diseases, cognitive function, and depression. Results: During the follow-up of eligible participants, 248 had died, 119 saw a decline in ADL, and 178 saw a decline in IADL. In fully adjusted models, having neither hobbies nor PIL was significantly associated with an increased risk of mortality (hazard ratio 2.08; 95% confidence interval [CI], 1.47–2.94, decline in ADL (odds ratio 2.74; 95% CI, 1.44–5.21, and decline in IADL (odds ratio 1.89; 95% CI, 1.01–3.55 compared to having both hobbies and PIL. Conclusions: Although effect modifications by cognitive functioning and depression cannot be ruled out, our findings suggest that having hobbies and PIL may extend not only longevity, but also healthy life expectancy among community-dwelling older adults.

The development of form two mathematics i-Think module (Mi-T2)

Science.gov (United States)

Yao, Foo Jing; Abdullah, Mohd Faizal Nizam Lee; Tien, Lee Tien

2017-05-01

This study aims to develop a training module i-THINK Mathematics Form Two (Mi-T2) to increase the higher-order thinking skills of students. The Mi-T2 training module was built based on the Sidek Module Development Model (2001). Constructivist learning theory, cognitive learning theory, i-THINK map and higher order thinking skills were the building blocks of the module development. In this study, researcher determined the validity and reliability of Mi-T2 module. The design being used in this study was descriptive study. To determine the needs of Mi-T2 module, questionnaires and literature review were used to collect data. When the need of the module was determined, the module was built and a pilot study was conducted to test the reliability of the Mi-T2 module. The pilot study was conducted at a secondary school in North Kinta, Perak. A Form Two class was selected to be the sample study through clustered random sampling. The pilot study was conducted for two months and one topic had been studied. The Mi-T2 module was evaluated by five expert panels to determine the content validity of the module. The instruments being used in the study were questionnaires about the necessity of the Mi-T2 module for guidance, questionnaires about the validity of the module and questionnaires concerning the reliability of the module. Statistical analysis was conducted to determine the validity and reliability coefficients of the Mi-T2 module. The content validity of Mi-T2 module was determined by Cohen's Kappa's (1968) agreement coefficient and the reliability of Mi-T2 module was determined by Cronbach Alpha's value scale. The content validity of Mi-T2 module was 0.89 and the Cronbach Alpha's value of Mi-T2 module was 0.911.

Parallelization Experience with Four Canonical Econometric Models Using ParMitISEM

NARCIS (Netherlands)

N. Basturk (Nalan); S. Grassi (Stefano); L.F. Hoogerheide (Lennart); H.K. van Dijk (Herman)

2016-01-01

textabstractThis paper presents the parallel computing implementation of the MitISEM algorithm, labeled Parallel MitISEM. The basic MitISEM algorithm, introduced by Hoogerheide, Opschoor and Van Dijk (2012), provides an automatic and flexible method to approximate a non-elliptical target density

Parallelization experience with four canonical econometric models using ParMitISEM

NARCIS (Netherlands)

Baştürk, N.; Grassi, S.; Hoogerheide, L.; van Dijk, H.K.

2016-01-01

This paper presents the parallel computing implementation of the MitISEM algorithm, labeled Parallel MitISEM. The basic MitISEM algorithm, introduced by Hoogerheide et al. (2012), provides an automatic and flexible method to approximate a non-elliptical target density using adaptive mixtures of

Physik gestern und heute: Visualisierung mit der Schlierenmethode

Science.gov (United States)

Heering, Peter

2006-07-01

Der Name des österreichischen Forschers Ernst Mach ist heute noch mit der Schallgeschwindigkeit verbunden. Diese Auszeichnung resultiert aus Machs Untersuchungen, wie sich Projektile mit Überschallgeschwindigkeit durch die Luft bewegen. Gerade in jüngster Zeit hat die Anwendung derartiger Methoden durch technische Modifikationen wieder einen Aufschwung erfahren.

MIT-CSR XIS Project

Science.gov (United States)

1998-01-01

This report outlines the proposers' progress toward MIT's contribution to the X-Ray Imaging Spectrometer (XIS) experiment on the Japanese ASTRO-E mission. The report discusses electrical system design, mechanical system design, and ground support equipment.

PCDDs/PCDFs, PCBs, and organochlorine pesticides in eggs of Eurasian sparrowhawks (Accipiter nisus), hobbies (Falco subbuteo), and northern goshawks (Accipiter gentilis) collected in the area of Berlin-Brandenburg, Germany.

Science.gov (United States)

Wiesmüller, T; Sömmer, P; Volland, M; Schlatterer, B

2002-05-01

Concentrations of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), polychlorinated biphenyls (PCBs), and organochlorine (OC) pesticides were measured in unsuccessfully hatched eggs of three different kinds of predatory birds: 3 eggs of sparrowhawks, 7 eggs of hobbies, and 16 eggs of goshawks collected in the German region of Berlin-Brandenburg. Using toxic equivalency factors for birds, eggs of hobbies contained mean concentrations of 478 pg TEQ/g fat and 551 pg TEQ/g fat contributed by PCDD/Fs and coplanar PCBs, respectively. For sparrowhawks the respective TCDD equivalents were 424 and 1278 pg/g fat; those for goshawks were 211 and 935 pg/g fat. The mean value of the summed concentrations of the PCB congeners 28, 52, 101, 138, 153, and 180 amounted to 11 microg/g fat in eggs of hobbies, 9.5 microg/g fat for sparrowhawks, and 16.1 microg/g fat for goshawks. Of the analyzed organochlorine pesticides the concentration of p,p'-DDE was highest (up to 273 microg/g); the concentration of the other OCs, with the exception of methoxychlor in eggs of goshawks (highest level of 10.6 microg/g fat), were negligible. In all cases the calculated toxicity of the coplanar PCBs surpassed the toxicity of the PCDD/Fs, at least by a factor of two. Due to the higher concentration of the coplanar PCB 77 compared to PCB 126 in eggs of hobbies, it is concluded that its metabolic excretion in this species is much lower than in sparrowhawks and goshawks.

Magnetosphere - Ionosphere - Thermosphere (MIT) Coupling at Jupiter

Science.gov (United States)

Yates, J. N.; Ray, L. C.; Achilleos, N.

2017-12-01

Jupiter's upper atmospheric temperature is considerably higher than that predicted by Solar Extreme Ultraviolet (EUV) heating alone. Simulations incorporating magnetosphere-ionosphere coupling effects into general circulation models have, to date, struggled to reproduce the observed atmospheric temperatures under simplifying assumptions such as azimuthal symmetry and a spin-aligned dipole magnetic field. Here we present the development of a full three-dimensional thermosphere model coupled in both hemispheres to an axisymmetric magnetosphere model. This new coupled model is based on the two-dimensional MIT model presented in Yates et al., 2014. This coupled model is a critical step towards to the development of a fully coupled 3D MIT model. We discuss and compare the resulting thermospheric flows, energy balance and MI coupling currents to those presented in previous 2D MIT models.

Parallelization experience with four canonical econometric models using ParMitISEM

NARCIS (Netherlands)

Bastürk, Nalan; Grassi, S.; Hoogerheide, L.; van Dijk, Herman K.

2016-01-01

This paper presents the parallel computing implementation of the MitISEM algorithm, labeled Parallel MitISEM. The basic MitISEM algorithm provides an automatic and flexible method to approximate a non-elliptical target density using adaptive mixtures of Student-t densities, where only a kernel of

Molekulargenetische Charakterisierung einer Familie mit Usher-Syndrom

OpenAIRE

Zimmer, AJ; Arndt, S; Aschendorff, A; Birkenhäger, R

2009-01-01

Einleitung: Das Usher-Syndrom definiert eine genetisch und klinisch heterogene autosomal rezessiv vererbte Erkrankung mit dem gleichzeitigen Auftreten von Innenohrschwerhörigkeit bis hin zur Taubheit, teilweise Vestibularisausfall und Netzhautdegeneration (Retinitis Pigmentosa). Bisher wird das Usher-Syndrom in drei verschiedene Hauptgruppen (USH1-3) mit unterschiedlicher phänotypischer Ausprägung eingeteilt. Für das Usher-Syndrom sind 12 Genorte bekannt, für die bereits acht Gene identifizi...

MIT domain of Vps4 is a Ca2+-dependent phosphoinositide-binding domain.

Science.gov (United States)

Iwaya, Naoko; Takasu, Hirotoshi; Goda, Natsuko; Shirakawa, Masahiro; Tanaka, Toshiki; Hamada, Daizo; Hiroaki, Hidekazu

2013-05-01

The microtubule interacting and trafficking (MIT) domain is a small protein module that is conserved in proteins of diverged function, such as Vps4, spastin and sorting nexin 15 (SNX15). The molecular function of the MIT domain is protein-protein interaction, in which the domain recognizes peptides containing MIT-interacting motifs. Recently, we identified an evolutionarily related domain, 'variant' MIT domain at the N-terminal region of the microtubule severing enzyme katanin p60. We found that the domain was responsible for binding to microtubules and Ca(2+). Here, we have examined whether the authentic MIT domains also bind Ca(2+). We found that the loop between the first and second α-helices of the MIT domain binds a Ca(2+) ion. Furthermore, the MIT domains derived from Vps4b and SNX15a showed phosphoinositide-binding activities in a Ca(2+)-dependent manner. We propose that the MIT domain is a novel membrane-associating domain involved in endosomal trafficking.

Optimierung der Hupkraftverteilung eines airbagintegrierten Automobillenkrades mit Hilfe einer Parameterstudie

OpenAIRE

Pietsch, Karsten

2011-01-01

Die Hupkraftverteilung eines airbagintegrierten Automobillenkrades wird mit Hilfe einer Parameterstudie in MathCAD so optimiert, das an jeder Krafteinleitungsposition die Hupe mit einer geforderten Mindestkraft betätigt werden kann. Nach der Modellierung in MathCAD der zugehörigen Geometrie und der Dimensionierung der Federlagerung ist das zugehörige mechanische Ersatzmodell mit Hilfe einer Parameterstudie verändert worden, so dass die Hupkraftforderung erfüllt wird.

Untersuchungen zum Riechvermögen bei Patienten mit schizophrenen Störungen

OpenAIRE

Minovi, A; Dombrowski, T; Brüne, M; Dazert, S; Juckel, G

2014-01-01

Einleitung: Riechstörungen werden bei Patienten mit einer Schizophrenie in vielen Studien beschrieben. Im Rahmen einer prospektiv angelegten Studie untersuchten wir das Riechvermögen von 18 Patienten mit einer Schizophrenie im Vergleich zu einer Kontrollgruppe (n=13). Weiterhin erfolgte eine immunhistochemische Untersuchung der Riechschleimhaut bei 8 Patienten mit einer Schizophrenie.Methoden: Die Riechprüfung erfolgte mit Hilfe der erweiterten Sniffin' Sticks-Testbatterie. Nach Biopsie der...

Liverpool Telescope and Liverpool Telescope 2

Science.gov (United States)

Copperwheat, C. M.; Steele, I. A.; Barnsley, R. M.; Bates, S. D.; Clay, N. R.; Jermak, H.; Marchant, J. M.; Mottram, C. J.; Piascik, A.; Smith, R. J.

2016-12-01

The Liverpool Telescope is a fully robotic optical/near-infrared telescope with a 2-metre clear aperture, located at the Observatorio del Roque de los Muchachos on the Canary Island of La Palma. The telescope is owned and operated by Liverpool John Moores University, with financial support from the UK's Science and Technology Facilities Council. The telescope began routine science operations in 2004 and is a common-user facility with time available through a variety of committees via an open, peer reviewed process. Seven simultaneously mounted instruments support a broad science programme, with a focus on transient follow-up and other time domain topics well suited to the characteristics of robotic observing. Development has also begun on a successor facility, with the working title `Liverpool Telescope 2', to capitalise on the new era of time domain astronomy which will be brought about by the next generation of survey facilities such as LSST. The fully robotic Liverpool Telescope 2 will have a 4-metre aperture and an improved response time. In this paper we provide an overview of the current status of both facilities.

MIT research reactor. Power uprate and utilization

Energy Technology Data Exchange (ETDEWEB)

Hu, Lin-Wen [Nuclear Reactor Laboratory, Massachusetts Inst. of Technology, Cambridge, MA (United States)

2012-03-15

The MIT Research Reactor (MITR) is a university research reactor located on MIT campus. and has a long history in supporting research and education. Recent accomplishments include a 20% power rate to 6 MW and expanding advanced materials fuel testing program. Another important ongoing initiative is the conversion to high density low enrichment uranium (LEU) monolithic U-Mo fuel, which will consist of a new fuel element design and power increase to 7 MW. (author)

Quantitative Datenanalyse: Arbeiten mit SPSS Statistics : Eine Einführung

OpenAIRE

Hoidn, Sabine

2012-01-01

Bei diesem Buch handelt es sich um eine verständliche Einführung in das Arbeiten mit dem quantitativen Datenanalyseprogramm SPSS Statistics. Die Studierenden setzen sich mit den Grundlagen zum Arbeiten mit SPSS Statistics auseinander, können selbständig eine SPSS Statistics-Datei erstellen, Daten einlesen, zusammenfügen und modifizieren, erfasste Daten managen und die gebräuchlichsten tabellarischen und grafischen Grundauswertungen sowie Analyseverfahren durchführen und interpretieren. Au...

Klinische Ergebnisse in der Behandlung der rezidivierenden respiratorischen Papillomatose mit Microdebrider, intraläsionaler Cidofovir-Injektion und Impfung mit Gardasil

OpenAIRE

Schäfer, Fabian Axel

2013-01-01

Die Rekurrierende Respiratorische Papillomatose (RRP) ist eine seltene Erkrankung, die Kinder, aber auch Erwachsene betrifft. Sie ist charakterisiert durch eine Proliferation benigner Plattenepithel-Papillome innerhalb des Aerodigestiv-Traktes mit dem Larynx als Prädilektionsstelle. Hervorgerufen wird die RRP durch eine orale Infektion mit Humanen Papillomviren (HPV) der Typen 6 oder 11. Bei aggressiven Verlaufsformen, die eine Vielzahl von Papillomabtragungen im Abstand von wenigen Monaten o...

Ghost telescope and ghost Fourier telescope with thermal light

International Nuclear Information System (INIS)

Gong Wenlin; Han Shensheng

2011-01-01

As important observation tools, telescopes are very useful in remote observations. We report a proof-of-principle experimental demonstration of ghost telescope scheme and show that, by measuring the intensity correlation of two light fields and only changing the position of the detector in the reference path, ghost telescope and ghost Fourier telescope can be obtained even if a single-pixel detector is fixed in Fresnel region of the object. Differences between conventional telescope and ghost telescope are also discussed.

Kleben von Kunststoff mit Metall

CERN Document Server

Brockmann, W; Käufer, H

1989-01-01

Das Buch behandelt das Kleben von Kunststoffen mit Metallen in einer fur den Praktiker verstandlichen und umsetzbaren Form. Es leitet zu Klebeverfahren an, die optimale Ergebnisse hinsichtlich Qualitat, Dauerhaftigkeit und Wirtschaftlichkeit liefern.

Laser mit instabilem Resonator fuer ringfoermige aktive Medien

OpenAIRE

Jarosch, U.K.; Habich, U.; Plum, H.D.

1996-01-01

Beschrieben werden Laser mit instabilen Resonatoren, die ringfoermige Medien effektiv ausnutzen, unabhaengig davon, ob es sich um feste, fluessige oder gasfoermige Medien handelt. Die Erfindung zeichnet sich dadurch aus, dass die Auskopplung des Strahles (5.1) eines Ringresonators entlang eines Spaltes oder eines Kreisringes ueber dem gesamten Umfang vorgesehen ist, wobei der Laserresonator durch Ringspiegel (1,2) mit torusfoermiger Spiegelflaeche gebildet und von den Waenden des Ringspaltes ...

Professionell entwickeln mit Java EE 7 das umfassende Handbuch

CERN Document Server

Salvanos, Alexander

2014-01-01

Ein praxisorientiertes Lehrbuch zur JEE 7 und zugleich ein Standardwerk, das Sie auf Ihrem Weg zum Enterprise-Entwickler begleitet. Inklusive Best Practices für leichtgewichtige Enterprise Applications, Standards zu servicebasierten Anwendungen, Persistence API, Dependency Injection, HTML5 und Performance-Tuning. Aus dem Inhalt: Grundlagen und Installation Software-Architektur mit Java EE Webanwendungen mit HTML5 und CSS3 Java Standard Tag Library Asynchrone Servlets und Non-blocking I/O Datenbanken anbinden mit der JDBC API Java Server Faces Datenbank-Organisation Java Persistence API Objektrelationales Mapping Transaktionssicherheit Performance-Tuning Internationalisierung Enterprise Java Beans WebSockets PrimeFaces Deployment Galileo Press heißt von jetzt an Rheinwerk Verlag.

The HETDEX pilot survey. V. The physical origin of Lyα emitters probed by near-infrared spectroscopy

Energy Technology Data Exchange (ETDEWEB)

Song, Mimi; Finkelstein, Steven L.; Gebhardt, Karl; Hill, Gary J.; Drory, Niv; Chonis, Taylor; Jogee, Shardha; Livermore, Rachael [Department of Astronomy, The University of Texas at Austin, 2515 Speedway, Stop C1400, Austin, TX 78712 (United States); Ashby, Matthew L. N.; Fazio, Giovanni G.; Huang, Jia-Sheng [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Blanc, Guillermo A. [Observatories of the Carnegie Institution of Washington, 813 Santa Barbara Street, Pasadena, CA 91101 (United States); Bridge, Joanna; Ciardullo, Robin; Gronwall, Caryl; Hagen, Alex; Schneider, Donald P. [Department of Astronomy and Astrophysics, The Pennsylvania State University, University Park, PA 16802 (United States); Fabricius, Maximilian; Gawiser, Eric [Department of Physics and Astronomy, Rutgers University, Piscataway, NJ 08854 (United States); Salmon, Brett, E-mail: mmsong@astro.as.utexas.edu [Department of Physics and Astronomy, Texas A and M University, College Station, TX 77843 (United States); and others

2014-08-10

We present the results from a Very Large Telescope/SINFONI and Keck/NIRSPEC near-infrared spectroscopic survey of 16 Lyα emitters (LAEs) at z = 2.1-2.5 in the COSMOS and GOODS-N fields discovered from the Hobby Eberly Telescope Dark Energy Experiment Pilot Survey. We detect rest-frame optical nebular lines (Hα and/or [O III] λ5007) for 10 of the LAEs and measure physical properties, including the star formation rate (SFR), gas-phase metallicity, gas mass fraction, and Lyα velocity offset. We find that LAEs may lie below the mass-metallicity relation for continuum-selected star-forming galaxies at the same redshift. The LAEs all show velocity shifts of Lyα relative to the systemic redshift ranging between +85 and +296 km s{sup –1} with a mean of +180 km s{sup –1}. This value is smaller than measured for continuum-selected star-forming galaxies at similar redshifts. The Lyα velocity offsets show a moderate correlation with the measured SFR (2.5σ), but no significant correlations are seen with the SFR surface density, specific SFR, stellar mass, or dynamical mass (≲1.5σ). Exploring the role of dust, kinematics of the interstellar medium (ISM), and geometry on the escape of Lyα photons, we find no signature of selective quenching of resonantly scattered Lyα photons. However, we also find no evidence that a clumpy ISM is enhancing the Lyα equivalent width. Our results suggest that the low metallicity in LAEs may be responsible for yielding an environment with a low neutral hydrogen column density and less dust, easing the escape of Lyα photons over that in continuum-selected star-forming galaxies.

The HETDEX pilot survey. V. The physical origin of Lyα emitters probed by near-infrared spectroscopy

International Nuclear Information System (INIS)

Song, Mimi; Finkelstein, Steven L.; Gebhardt, Karl; Hill, Gary J.; Drory, Niv; Chonis, Taylor; Jogee, Shardha; Livermore, Rachael; Ashby, Matthew L. N.; Fazio, Giovanni G.; Huang, Jia-Sheng; Blanc, Guillermo A.; Bridge, Joanna; Ciardullo, Robin; Gronwall, Caryl; Hagen, Alex; Schneider, Donald P.; Fabricius, Maximilian; Gawiser, Eric; Salmon, Brett

2014-01-01

We present the results from a Very Large Telescope/SINFONI and Keck/NIRSPEC near-infrared spectroscopic survey of 16 Lyα emitters (LAEs) at z = 2.1-2.5 in the COSMOS and GOODS-N fields discovered from the Hobby Eberly Telescope Dark Energy Experiment Pilot Survey. We detect rest-frame optical nebular lines (Hα and/or [O III] λ5007) for 10 of the LAEs and measure physical properties, including the star formation rate (SFR), gas-phase metallicity, gas mass fraction, and Lyα velocity offset. We find that LAEs may lie below the mass-metallicity relation for continuum-selected star-forming galaxies at the same redshift. The LAEs all show velocity shifts of Lyα relative to the systemic redshift ranging between +85 and +296 km s –1 with a mean of +180 km s –1 . This value is smaller than measured for continuum-selected star-forming galaxies at similar redshifts. The Lyα velocity offsets show a moderate correlation with the measured SFR (2.5σ), but no significant correlations are seen with the SFR surface density, specific SFR, stellar mass, or dynamical mass (≲1.5σ). Exploring the role of dust, kinematics of the interstellar medium (ISM), and geometry on the escape of Lyα photons, we find no signature of selective quenching of resonantly scattered Lyα photons. However, we also find no evidence that a clumpy ISM is enhancing the Lyα equivalent width. Our results suggest that the low metallicity in LAEs may be responsible for yielding an environment with a low neutral hydrogen column density and less dust, easing the escape of Lyα photons over that in continuum-selected star-forming galaxies.

THE HOT-JUPITER KEPLER-17b: DISCOVERY, OBLIQUITY FROM STROBOSCOPIC STARSPOTS, AND ATMOSPHERIC CHARACTERIZATION

International Nuclear Information System (INIS)

Désert, Jean-Michel; Charbonneau, David; Ballard, Sarah; Carter, Joshua A.; Quinn, Samuel N.; Fressin, François; Latham, David W.; Torres, Guillermo; Demory, Brice-Olivier; Fortney, Jonathan J.; Cochran, William D.; Endl, Michael; Isaacson, Howard T.; Knutson, Heather A.; Buchhave, Lars A.; Bryson, Stephen T.; Rowe, Jason F.; Borucki, William J.; Batalha, Natalie M.; Brown, Timothy M.

2011-01-01

This paper reports the discovery and characterization of the transiting hot giant exoplanet Kepler-17b. The planet has an orbital period of 1.486 days, and radial velocity measurements from the Hobby-Eberly Telescope show a Doppler signal of 419.5 +13.3 –15.6 m s –1 . From a transit-based estimate of the host star's mean density, combined with an estimate of the stellar effective temperature T eff = 5630 ± 100 from high-resolution spectra, we infer a stellar host mass of 1.06 ± 0.07 M ☉ and a stellar radius of 1.02 ± 0.03 R ☉ . We estimate the planet mass and radius to be M P = 2.45 ± 0.11 M J and R P = 1.31 ± 0.02 R J . The host star is active, with dark spots that are frequently occulted by the planet. The continuous monitoring of the star reveals a stellar rotation period of 11.89 days, eight times the planet's orbital period; this period ratio produces stroboscopic effects on the occulted starspots. The temporal pattern of these spot-crossing events shows that the planet's orbit is prograde and the star's obliquity is smaller than 15°. We detected planetary occultations of Kepler-17b with both the Kepler and Spitzer Space Telescopes. We use these observations to constrain the eccentricity, e, and find that it is consistent with a circular orbit (e 3.6μm = 1880 ± 100 K and T 4.5μm = 1770 ± 150 K. We measure the optical geometric albedo A g in the Kepler bandpass and find A g = 0.10 ± 0.02. The observations are best described by atmospheric models for which most of the incident energy is re-radiated away from the day side.

Parallelization Experience with Four Canonical Econometric Models Using ParMitISEM

Directory of Open Access Journals (Sweden)

Nalan Baştürk

2016-03-01

Full Text Available This paper presents the parallel computing implementation of the MitISEM algorithm, labeled Parallel MitISEM. The basic MitISEM algorithm provides an automatic and flexible method to approximate a non-elliptical target density using adaptive mixtures of Student-t densities, where only a kernel of the target density is required. The approximation can be used as a candidate density in Importance Sampling or Metropolis Hastings methods for Bayesian inference on model parameters and probabilities. We present and discuss four canonical econometric models using a Graphics Processing Unit and a multi-core Central Processing Unit version of the MitISEM algorithm. The results show that the parallelization of the MitISEM algorithm on Graphics Processing Units and multi-core Central Processing Units is straightforward and fast to program using MATLAB. Moreover the speed performance of the Graphics Processing Unit version is much higher than the Central Processing Unit one.

ATST telescope mount: telescope of machine tool

Science.gov (United States)

Jeffers, Paul; Stolz, Günter; Bonomi, Giovanni; Dreyer, Oliver; Kärcher, Hans

2012-09-01

The Advanced Technology Solar Telescope (ATST) will be the largest solar telescope in the world, and will be able to provide the sharpest views ever taken of the solar surface. The telescope has a 4m aperture primary mirror, however due to the off axis nature of the optical layout, the telescope mount has proportions similar to an 8 meter class telescope. The technology normally used in this class of telescope is well understood in the telescope community and has been successfully implemented in numerous projects. The world of large machine tools has developed in a separate realm with similar levels of performance requirement but different boundary conditions. In addition the competitive nature of private industry has encouraged development and usage of more cost effective solutions both in initial capital cost and thru-life operating cost. Telescope mounts move relatively slowly with requirements for high stability under external environmental influences such as wind buffeting. Large machine tools operate under high speed requirements coupled with high application of force through the machine but with little or no external environmental influences. The benefits of these parallel development paths and the ATST system requirements are being combined in the ATST Telescope Mount Assembly (TMA). The process of balancing the system requirements with new technologies is based on the experience of the ATST project team, Ingersoll Machine Tools who are the main contractor for the TMA and MT Mechatronics who are their design subcontractors. This paper highlights a number of these proven technologies from the commercially driven machine tool world that are being introduced to the TMA design. Also the challenges of integrating and ensuring that the differences in application requirements are accounted for in the design are discussed.

Helicobacter sp. MIT 01-6451 infection during fetal and neonatal life in laboratory mice.

Science.gov (United States)

Yamanaka, Hitoki; Nakanishi, Tai; Takagi, Toshikazu; Ohsawa, Makiko; Kubo, Noriaki; Yamamoto, Naoto; Takemoto, Takahira; Ohsawa, Kazutaka

2015-01-01

Helicobacter sp. MIT 01-6451 has been detected in SPF mice kept in Japan. To characterize strain MIT 01-6451, its infection route during fetal and neonatal life and effects on pregnancy were investigated using immunocompetent and immunodeficient mouse strains (BALB/c, C57BL/6, and SCID). MIT 01-6451 was detected in the uterus, vagina, and mammary glands of 50% of infected SCID mice, whereas these tissues were all negative in immunocompetent mice. No fetal infections with MIT 01-6451 were detected at 16-18 days after pregnancy in any mouse strain. In newborn mice, MIT 01-6451 was detected in intestinal tissue of C57BL/6 and SCID mice at 9-11 days after birth, but not in BALB/c mice. The IgA and IgG titers to MIT 01-6451 in sera of C57BL/6 female mice were significantly lower than those of BALB/c mice. Although no significant differences in the number of newborns per litter were observed between MIT 01-6451-infected and MIT 01-6451-free dams, the birth rate was lower in infected SCID mice than in control SCID mice. The present results indicated that MIT 01-6451 infects newborn mice after birth rather than by vertical transmission to the fetus via the placenta and that MIT 01-6451 infection shows opportunistically negative effects on the birth rate. In addition, the maternal immune response may affect infection of newborn mice with MIT 01-6451 through breast milk.

Evaluation of the MIT RMID 1000 system for the identification of Listeria species.

Science.gov (United States)

Ricardi, John; Haavig, David; Cruz, Lasaunta; Paoli, George; Gehring, Andrew

2010-01-01

The Micro Imaging Technology (MIT) 1000 Rapid Microbial Identification (RMID) System is a device that uses the principles of light scattering coupled with proprietary algorithms to identify bacteria after being cultured and placed in a vial of filtered water. This specific method is for pure culture identification of Listeria spp. A total of 81 microorganisms (55 isolates) were tested by the MIT 1000 System, of which 25 were Listeria spp. and 30 a variety of other bacterial species. In addition, a total of 406 tests over seven different ruggedness parameters were tested by the MIT 1000 System to determine its flexibility to the specifications stated in the MIT 1000 System User Guide in areas where they might be deviated by a user to shorten the test cycle. Overall, MIT concluded that the MIT 1000 System had an accuracy performance that should certify this Performance Test Method for the identification of Listeria spp. This report discusses the tests performed, results achieved, and conclusions, along with several reference documents to enable a higher understanding of the technology used by the MIT 1000 System.

Simulating the Sky as Seen by the Square Kilometer Array using the MIT Array Performance Simulator (MAPS)

Science.gov (United States)

Matthews, Lynn D.; Cappallo, R. J.; Doeleman, S. S.; Fish, V. L.; Lonsdale, C. J.; Oberoi, D.; Wayth, R. B.

2009-05-01

The Square Kilometer Array (SKA) is a proposed next-generation radio telescope that will operate at frequencies of 0.1-30 GHz and be 50-100 times more sensitive than existing radio arrays. Meeting the performance goals of this instrument will require innovative new hardware and software developments, a variety of which are now under consideration. Key to evaluating the performance characteristics of proposed SKA designs and testing the feasibility of new data calibration and processing algorithms is the ability to carry out realistic simulations of radio wavelength arrays under a variety of observing conditions. The MIT Array Performance Simulator (MAPS) (http://www.haystack.mit.edu/ast/arrays/maps/index.html) is an observations simulation package designed to achieve this goal. MAPS accepts an input source list or sky model and generates a model visibility set for a user-defined "virtual observatory'', incorporating such factors as array geometry, primary beam shape, field-of-view, and time and frequency resolution. Optionally, effects such as thermal noise, out-of-beam sources, variable station beams, and time/location-dependent ionospheric effects can be included. We will showcase current capabilities of MAPS for SKA applications by presenting results from an analysis of the effects of realistic sky backgrounds on the achievable image fidelity and dynamic range of SKA-like arrays comprising large numbers of small-diameter antennas.

MIT CSAIL and Lincoln Laboratory Task Force Report

Science.gov (United States)

2016-08-01

funded through MIT LL, most notably through by the MIT LL Technology Office (TO). TO funding has come through a diverse set of venues: ASD (R&E) Line...many and varied opportunities to participate could better cohere research interests at each institution and between them as well. 3.4.2 Autonomy-at...applications. Near-data processing is about migrating selected processing operations from the central processing unit (CPU) of traditional computer

Die Last mit der Lust

Directory of Open Access Journals (Sweden)

Lutz Sauerteig

2004-03-01

Full Text Available Robert Jütte legt mit Lust ohne Last eine umfassende, allgemeinverständliche und spannend zu lesende Geschichte der Empfängnisverhütung von der Antike bis in die unmittelbare Gegenwart vor.

Art, auto-mechanics, and supramolecular chemistry. A merging of hobbies and career.

Science.gov (United States)

Anslyn, Eric V

2016-01-01

While the strict definition of supramolecular chemistry is "chemistry beyond the molecule", meaning having a focus on non-covalent interactions, the field is primarily associated with the creation of synthetic receptors and self-assembly. For synthetic ease, the receptors and assemblies routinely possess a high degree of symmetry, which lends them an aspect of aesthetic beauty. Pictures of electron orbitals similarly can be seen as akin to works of art. This similarity was an early draw for me to the fields of supramolecular chemistry and molecular orbital theory, because I grew up in a household filled with art. In addition to art, my childhood was filled with repairing and constructing mechanical entities, such as internal combustion motors, where many components work together to achieve a function. Analogously, the field of supramolecular chemistry creates systems of high complexity that achieve functions or perform tasks. Therefore, in retrospect a career in supramolecular chemistry appears to be simply an extension of childhood hobbies involving art and auto-mechanics.

SUBSTELLAR-MASS COMPANIONS TO THE K-DWARF BD+14 4559 AND THE K-GIANTS HD 240210 AND BD+20 2457

International Nuclear Information System (INIS)

Niedzielski, A.; Nowak, G.; Adamow, M.; Wolszczan, A.

2009-01-01

We present the discovery of substellar-mass companions to three stars by the ongoing Penn State-Torun Planet Search conducted with the 9.2 m Hobby-Eberly Telescope. The K2-dwarf, BD+14 4559, has a 1.5 M J minimum mass companion with the orbital period of 269 days and shows a non-linear, long-term radial velocity (RV) trend, which indicates a possible presence of another planet-mass body in the system. The K3-giant, HD 240210, exhibits RV variations that require modeling with multiple orbits, but the available data are not yet sufficient to do it unambiguously. A tentative, one-planet model calls for a 5.2 M J minimum mass planet in a 502 day orbit around the star. The most massive of the three stars, the K2-giant, BD+20 2457, whose estimated mass is 2.8 ± 1.5 M sun , has two companions with the respective minimum masses of 21.4 M J and 12.5 M J and orbital periods of 380 and 622 days. Depending on the unknown inclinations of the orbits, the currently very uncertain mass of the star, and the dynamical properties of the system, it may represent the first detection of two brown dwarf-mass companions orbiting a giant. The existence of such objects will have consequences for the interpretation of the so-called brown dwarf desert known to exist in the case of solar-mass stars.

THE CHEMICAL ABUNDANCES OF STARS IN THE HALO (CASH) PROJECT. II. A SAMPLE OF 14 EXTREMELY METAL-POOR STARS ,

International Nuclear Information System (INIS)

Hollek, Julie K.; Sneden, Christopher; Shetrone, Matthew; Frebel, Anna; Roederer, Ian U.; Beers, Timothy C.; Kang, Sung-ju; Thom, Christopher

2011-01-01

We present a comprehensive abundance analysis of 20 elements for 16 new low-metallicity stars from the Chemical Abundances of Stars in the Halo (CASH) project. The abundances have been derived from both Hobby-Eberly Telescope High Resolution Spectrograph snapshot spectra (R ∼15, 000) and corresponding high-resolution (R ∼35, 000) Magellan Inamori Kyocera Echelle spectra. The stars span a metallicity range from [Fe/H] from –2.9 to –3.9, including four new stars with [Fe/H] < –3.7. We find four stars to be carbon-enhanced metal-poor (CEMP) stars, confirming the trend of increasing [C/Fe] abundance ratios with decreasing metallicity. Two of these objects can be classified as CEMP-no stars, adding to the growing number of these objects at [Fe/H]< – 3. We also find four neutron-capture-enhanced stars in the sample, one of which has [Eu/Fe] of 0.8 with clear r-process signatures. These pilot sample stars are the most metal-poor ([Fe/H] ∼< –3.0) of the brightest stars included in CASH and are used to calibrate a newly developed, automated stellar parameter and abundance determination pipeline. This code will be used for the entire ∼500 star CASH snapshot sample. We find that the pipeline results are statistically identical for snapshot spectra when compared to a traditional, manual analysis from a high-resolution spectrum.

A geometrodynamical approach to the MIT confinement scheme

International Nuclear Information System (INIS)

Martellini, M.; Sodano, P.

1978-01-01

Starting from the strong gravity theory of Salam-Isham-Strathdee the M.I.T. bag is identified as a certain region of the global extension of a De Sitter-Schwarzschild solution. As a result the M.I.T. bag radius, a geometrical interpretation of the binding Lagrangian term and a rate of decaying of the ''bag manifold'' into the flat space (which, however, does not lead to observable quark wave functions) are obtained. (author)

Final Technical Report for the MIT Annular Fuel Research Project

International Nuclear Information System (INIS)

Mujid S. Kazimi; Pavel Hejzlar

2008-01-01

MIT-NFC-PR-082 (January 2006) Abstract This summary provides an overview of the results of the U.S. DOE funded NERI (Nuclear Research Energy Initiative) program on development of the internally and externally cooled annular fuel for high power density PWRs. This new fuel was proposed by MIT to allow a substantial increase in power density (on the order of 30% or higher) while maintaining or improving safety margins. A comprehensive study was performed by a team consisting of MIT (lead organization), Westinghouse Electric Corporation, Gamma Engineering Corporation, Framatome ANP(formerly Duke Engineering) and Atomic Energy of Canada Limited

Phylogenetic relationships of the Gomphales based on nuc-25S-rDNA, mit-12S-rDNA, and mit-atp6-DNA combined sequences

Science.gov (United States)

Admir J. Giachini; Kentaro Hosaka; Eduardo Nouhra; Joseph Spatafora; James M. Trappe

2010-01-01

Phylogenetic relationships among Geastrales, Gomphales, Hysterangiales, and Phallales were estimated via combined sequences: nuclear large subunit ribosomal DNA (nuc-25S-rDNA), mitochondrial small subunit ribosomal DNA (mit-12S-rDNA), and mitochondrial atp6 DNA (mit-atp6-DNA). Eighty-one taxa comprising 19 genera and 58 species...

Spillerum og mit eget rum

DEFF Research Database (Denmark)

2014-01-01

Undervisningsmaterialet Spillerum udviklet som APP til Ipad med interaktive muligheder. Spillerum som APP - et interaktivt undervisningsmateriale, hvor man ud over at bruge det originale materiale Spillerum elektronisk kan skabe sit eget billedbaserede rum "Mit eget rum" som udgangspunkt for dialog....

Grundlegende Steuerungsverfahren im heterogenen Logistiknetz mit Kanban

Science.gov (United States)

Dickmann, Eva; Dickmann, Philipp; Lödding, Hermann; Möller, Niklas; Rücker, Thomas; Schneider, Herfried M.; Zäh, Michael F.

In vielen Unternehmen werden heterogene (verschiedene) Steuerungen in einem abgestimmten Konzept kombiniert. Je nach Anwendungsfall und Rahmenbedingungen werden Kombinationen allgemein bekannter Steuerungen oder Steuerungsvarianten gemischt eingesetzt, um eine optimale Steuerung für unterschiedliche Fälle zu erreichen. Hierbei stehen neben den bekannten und weit verbreiteten Methoden, wie Material Requirements Planning (MRP) oder Kanban, auch weniger bekannte oder neue Methoden zur Auswahl, wie die Produktionssteuerung mit dezentraler, bestandsorientierter Fertigungsregelung (DBF). Kanban ist ein simples und effizientes Steuerungskonzept, das in der klassischen Form für spezifische einfache Anwendungsfälle umsetzbar ist. Hochentwickelte Steuerungsalgorithmen können helfen, komplexe Abläufe optimal abzubilden. Mit einer grundlegenden Vereinfachung der Abläufe kann allerdings in vielen Fällen ein wesentlich stärkerer und umfassender Verbesserungseffekt erzielt werden. Die wesentliche Fragestellung sollte folglich lauten: Warum ist der Ablauf nicht mit einer einfachen Steuerung wie Kanban abzubilden? Um die Vorteile des Konzepts auch in untypischen Bereichen anwenden zu können, sind jedoch verschiedene Varianten oder Kanban-ähnliche Steuerungsmethoden entstanden. Darüber hinaus sind in der Praxis hybride Steuerungen im Einsatz, welche so kombiniert werden, dass die Zusammensetzung anspruchsvolle Eigenschaftsbilder noch exakt abbildet. In der Praxis basieren die Steuerungsentscheidungen nur zu einem kleinen Teil auf den eigentlichen Steuerungsalgorithmen, wie sie uns das MRP-System zur Verfügung stellt. Moderne Steuerungswelten" schließen alle relevanten Informationsquellen in eine heterogene Entscheidungsmatrix mit ein. Letztlich zählt nicht, ob die Entscheidung auf den Informationen aus dem MRP-System oder auf Softfacts basierend getroffen wurde, sondern nur, ob die Entscheidung erfolgreich war.

Physikalische Grundlagen von chemischen Raman-Sensoren mit Schwerpunkt auf faseroptischen SERS-Sonden

OpenAIRE

Viets, Carmen

2001-01-01

Faseroptische SERS-Sensoren wurden durch die Beschichtung der Endflächen von optischen Fasern mit rauhen Metallfilmen erzeugt. Zu den verschiedenen Präparationstechniken, die angewendet und verglichen wurden, gehörten das langsame Aufdampfen von Metall-Inselfilmen und das Bedampfen von Nanopartikeln, aufgerauhten oder elektronenlithographisch strukturierten Oberflächen mit Metallfilmen. Der Einfluß der Laserleistung auf die Messungen mit SERS-Sensoren wurde untersucht, und es wurden maximale ...

Suche nach solaren Axionen mit dem CCD-Detektor in CAST (CERN Axion Solar Telescope)

CERN Document Server

Kang, Donghwa

2007-01-01

The CERN Axion Solar Telescope (CAST) experiment at CERN searches for solar axions with energies in the keV range. Axions could be produced in the Sun's core by the interaction of thermal photons with virtual photons of the strong electromagnetic field. In this experiment, the solar axions can be converted to photons in the field of a 9 Tesla superconducting magnet. At both ends of the 10 m long dipole magnet, three different X-ray detectors were installed, which are sensitive in the interesting photon energy range. This thesis is devoted to the determination of an upper limit on the axion-photon coupling constant g$_{a\\gamma}$. The analysis is based on the data taken by the CCD detector in the CAST experiment during the years 2003 and 2004. First results of the 2003 data taking were published showing no significant signal above background. However, these results constrain the upper limit of the axion-photon coupling constant by a factor 5 compared to previous axion search experiments. Moreover, the result of...

The stargazer's guide to the night sky

CERN Document Server

Lisle, Jason, Dr

2012-01-01

Explore the night sky, identify stars, constellations, and even planets. Stargaze with a telescope, binoculars, or even your naked eye. Allow Dr. Jason Lisle, a research scientist with a masters and PhD in astrophysics, to guide you in examining the beauty of God's Creation with 150 full color star-charts. Learn the best ways and optimal times to observe planets and stars with easy to use illustrations. Create or expand the hobby of stargazing; an outdoor, educational hobby to enjoy with friends or family.

Der Ritter mit dem Hemd : drei Fassungen einer mittelalterlichen Erzählung

OpenAIRE

Dunphy, Graeme

2011-01-01

Unter den zahlreichen Motiven, die in der mittelalterlichen Literatur mit Frauendienst verbunden sind, gehört das vom Ritter mit dem Hemd zu den besonders interessanten. Es erscheint zunächst in dem ersten von fünf Fabliaux aus einer verlorenen Turiner Handschrift, die dem sonst unbekannten altfranzösischen Dichter Jacques de Baisieux zugeschrieben werden, einer heiteren Kurzgeschichte mit dem Titel "Des trois chevaliers et del chainse". In der vorliegenden Untersuchung gilt es, der Frage der...

Art, auto-mechanics, and supramolecular chemistry. A merging of hobbies and career

Directory of Open Access Journals (Sweden)

Eric V. Anslyn

2016-02-01

Full Text Available While the strict definition of supramolecular chemistry is “chemistry beyond the molecule”, meaning having a focus on non-covalent interactions, the field is primarily associated with the creation of synthetic receptors and self-assembly. For synthetic ease, the receptors and assemblies routinely possess a high degree of symmetry, which lends them an aspect of aesthetic beauty. Pictures of electron orbitals similarly can be seen as akin to works of art. This similarity was an early draw for me to the fields of supramolecular chemistry and molecular orbital theory, because I grew up in a household filled with art. In addition to art, my childhood was filled with repairing and constructing mechanical entities, such as internal combustion motors, where many components work together to achieve a function. Analogously, the field of supramolecular chemistry creates systems of high complexity that achieve functions or perform tasks. Therefore, in retrospect a career in supramolecular chemistry appears to be simply an extension of childhood hobbies involving art and auto-mechanics.

Rekonstruktion mit Netz beim komplexen Prolaps der Frau: Was hilft es der Patientin wirklich?

Directory of Open Access Journals (Sweden)

Hierl J

2010-01-01

Full Text Available Einleitung: Der komplexe Genitaldeszensus der Frau geht oftmals mit einer deutlichen Einschränkung der Lebensqualität (LQ einher. Dennoch ist der Endpunkt der meisten klinischen Analysen rein anatomischer und funktioneller Natur. In der vorliegenden Untersuchung wurden die Einflüsse der operativen Rekonstruktion mit einem Netz prospektiv auf die LQ evaluiert. Patienten und Methoden: Bei insgesamt 111 Patientinnen mit Deszensus erfolgte zwischen 08/2005 und 12/2007 eine operative Versorgung mittels vaginaler Netzeinlage (anteriorer bzw. kompletter Mesh-Repair. Die LQ wurde prospektiv prä- und postoperativ anhand standardisierter LQ-Fragebögen erfasst. Ergebnisse: Präoperativ zeigte sich bei den Patientinnen eine signifikant reduzierte LQ gegenüber einem Normalkollektiv (p 0,01. Bei 7 % der Patientinnen mit anteriorem, und bei 11 % mit komplettem Mesh-Repair lag postoperativ kein adäquates klinisches Ergebnis vor. In diesem Kollektiv zeigte sich kein signifikanter Unterschied in den LQ-Tests prä- und postoperativ. Bei gutem postoperativem Ergebnis zeigte sich in der Gruppe mit anteriorer Netzeinlage lediglich bei 45 % (p = 0,021, bei kompletter Netzeinlage nur bei 31 % (p = 0,041 eine signifikant verbesserte LQ. Bei kleiner Fallzahl und kurzem Nachbeobachtungszeitraum kann eine gültige Aussage bezüglich der LQ nach Deszensuschirurgie mit Netzeinlage jedoch noch nicht getroffen werden.

Fallstudie SIG - Supply Chain Prototyp mit Coca Cola Beverages

OpenAIRE

Senger, Enrico

2003-01-01

SIG, ein führender Lieferant von Verpackungsmaterialien für Getränke, hat mit Coca Cola CPFR, collaborative planning, forecasting and replenishment realisiert. Das Unternehmen kann elektronisch und ohne Zeitverzug (vorher mit bis zu 15 Tagen Verspätung) auf die Lagerbestände und Verkaufsvorhersagen bei Coca Cola zugreifen. Coca Cola erhält die exakten Liefermengen und zeiten. Coca Cola konnte dadurch den Lagerbestand von Verpackungsmaterial um 50% senken. Dies reduziert die Bearbeitungszeit d...

Thin Mirror Shaping Technology for High-Throughput X-ray Telescopes

Science.gov (United States)

Schattenburg, Mark

This proposal is submitted to the NASA Research Opportunities in Space and Earth Sciences program (ROSES-2012) in response to NASA Research Announcement NNH12ZDA001N- APRA. It is targeted to the Astronomy and Astrophysics Research and Analysis (APRA) program element under the Supporting Technology category. Powerful x-ray telescope mirrors are critical components of a raft of small-to-large mission concepts under consideration by NASA. The science questions addressed by these missions have certainly never been more compelling and the need to fulfill NASA s core missions of exploring the universe and strengthening our nation s technology base has never been greater. Unfortunately, budgetary constraints are driving NASA to consider the cost/benefit and risk factors of new missions more carefully than ever. New technology for producing x-ray telescopes with increased resolution and collecting area, while holding down cost, are key to meeting these goals and sustaining a thriving high-energy astrophysics enterprise in the US. We propose to develop advanced technology which will lead to thin-shell x-ray telescope mirrors rivaling the Chandra x-ray telescope in spatial resolution but with 10-100X larger area all at significantly reduced weight, risk and cost. The proposed effort builds on previous research at MIT and complements NASA-supported research at other institutions. We are currently pursuing two thin-mirror technology development tracks which we propose to extend and accelerate with NASA support. The first research track utilizes rapidly-maturing thermal glass slumping technology which uses porous ceramic air-bearing mandrels to shape glass mirrors without touching, thus avoiding surface-induced mid-range spatial frequency ripples. A second research track seeks to remove any remaining mid- to long-range errors in mirrors by using scanning ion-beam implant to impart small, highly deterministic and very stable amounts of stress into thin glass, utilizing local

Overview of MIT, ADIP irradiation experiments

International Nuclear Information System (INIS)

Kohse, G.; Harling, O.K.; Grant, N.J.

1985-06-01

Various rapidly solidified austenitic, ferritic and copper alloys have been produced at MIT for inclusion in ADIP neutron irradiation experiments. A brief summary of the alloys and their preparation and the achieved or projected irradiation parameters is provided

Intraläsionale Therapie niedrig maligner primär kutaner B-Zell-Lymphome mit Anti-CD20-Antikörper: Nebenwirkungen korrelieren mit gutem klinischen Ansprechen.

Science.gov (United States)

Eberle, Franziska C; Holstein, Julia; Scheu, Alexander; Fend, Falko; Yazdi, Amir S

2017-03-01

Die intraläsionale Gabe von Anti-CD20-Antikörpern (Rituximab) wurde als effektive Therapieoption für Patienten mit niedrig malignen primär kutanen B-Zell-Lymphomen beschrieben. Bis heute wurden allerdings keine Parameter identifiziert, welche reproduzierbar ein gutes klinisches Ansprechen dieser Therapie vorhersagen. Ziel dieser Studie ist, sowohl das klinische Ansprechen und die unerwünschten Nebenwirkungen als auch die Patientenwahrnehmung hinsichtlich intraläsionaler Injektionen von anti-CD20-Antikörpern zur Behandlung indolenter primär kutaner B-Zell-Lymphome im Vergleich mit anderen Therapien zu evaluieren. Elf Patienten mit einem primär kutanen B-Zell-Lymphom, namentlich primär kutanes Keimzentrumslymphom (n = 9) und primär kutanes Marginalzonenlymphom (n = 2), welche mittels intraläsionalem Anti-CD20-Antikörper behandelt wurden, wurden retrospektiv evaluiert hinsichtlich der Ansprechrate und unerwünschter Nebenwirkungen sowie in Bezug auf deren Selbsteinschätzung dieser und anderer Therapien des primär kutanen B-Zell-Lymphoms. Patienten, deren primär kutanes B-Zell-Lymphom mittels intraläsionaler Gabe von Anti-CD20-Antikörper behandelt wurde, zeigten ein komplettes oder partielles Ansprechen in 45 % beziehungsweise 27 % aller Patienten. Speziell Patienten mit grippeähnlichen Symptomen nach erfolgter Injektion zeigten ein gutes Ansprechen. Die Mehrheit der Patienten empfand die Therapie mit Rituximab als die beste Therapie im Vergleich zu anderen Therapien wie beispielsweise chirurgische Exzision oder Radiotherapie. Intraläsionales Rituximab ist eine effektive Therapie mit hoher Patientenzufriedenheit. Starke therapiebedingte Nebenwirkungen wie Fieber, Schüttelfrost und Kopfschmerzen nach Gabe von Rituximab könnten als Indikator für gute Wirksamkeit dienen. © 2017 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

Life-threatening hobbies in the youth? Two autoptic cases suggesting arrhythmogenic right ventricular cardiomyopathy.

Science.gov (United States)

Wingenfeld, Lisa; Freislederer, Andreas; Schulze-Bahr, Eric; Paul, Matthias; Bajanowski, Thomas

2007-08-24

Determining the cause for the sudden death in young adults tends to be complex and difficult. Two cases of death of young people were autoptically investigated who died suddenly while carrying out their hobbies (a 22-year-old male musician and a 20-year-old female dancer). In both cases neither the police investigation, the autopsy, nor the toxicological investigations gave any relevant results. However, when investigating the histology fatty and fibrotic tissue in the right ventricle of the myocardium were found, whereas the myocytes proved to be degenerated--typical for arrhythmogenic right ventricular cardiomyopathy (ARVC). It is important to consider the possibility of heart rhythm failure if a clear reason for sudden death in young adults cannot be detected. Heart rhythm failure often involves the genetic background of the case, which suggests that genetic analysis should be carried out as a supportive means of diagnostics.

Mobile-IT Education (MIT.EDU): M-Learning Applications for Classroom Settings

Science.gov (United States)

Sung, M.; Gips, J.; Eagle, N.; Madan, A.; Caneel, R.; DeVaul, R.; Bonsen, J.; Pentland, A.

2005-01-01

In this paper, we describe the Mobile-IT Education (MIT.EDU) system, which demonstrates the potential of using a distributed mobile device architecture for rapid prototyping of wireless mobile multi-user applications for use in classroom settings. MIT.EDU is a stable, accessible system that combines inexpensive, commodity hardware, a flexible…

Biotechnology Process Engineering Center at MIT - Overview

Science.gov (United States)

| Facsimile (617) 253-2400 | e-mail: bpec-www@mit.edu THERAPEUTIC GENE BIOTECHNOLOGY INDUSTRIAL CONSORTIUM Board (ICAB) in Therapeutic Gene Biotechnology. ICAB Member Representatives review our research progress

MIT pebble bed reactor project

Energy Technology Data Exchange (ETDEWEB)

Kadak, Andrew C. [Massachusetts Institute of Technology, Cambridge (United States)

2007-03-15

The conceptual design of the MIT modular pebble bed reactor is described. This reactor plant is a 250 Mwth, 120 Mwe indirect cycle plant that is designed to be deployed in the near term using demonstrated helium system components. The primary system is a conventional pebble bed reactor with a dynamic central column with an outlet temperature of 900 C providing helium to an intermediate helium to helium heat exchanger (IHX). The outlet of the IHX is input to a three shaft horizontal Brayton Cycle power conversion system. The design constraint used in sizing the plant is based on a factory modularity principle which allows the plant to be assembled 'Lego' style instead of constructed piece by piece. This principle employs space frames which contain the power conversion system that permits the Lego-like modules to be shipped by truck or train to sites. This paper also describes the research that has been conducted at MIT since 1998 on fuel modeling, silver leakage from coated fuel particles, dynamic simulation, MCNP reactor physics modeling and air ingress analysis.

MIT pebble bed reactor project

International Nuclear Information System (INIS)

Kadak, Andrew C.

2007-01-01

The conceptual design of the MIT modular pebble bed reactor is described. This reactor plant is a 250 Mwth, 120 Mwe indirect cycle plant that is designed to be deployed in the near term using demonstrated helium system components. The primary system is a conventional pebble bed reactor with a dynamic central column with an outlet temperature of 900 C providing helium to an intermediate helium to helium heat exchanger (IHX). The outlet of the IHX is input to a three shaft horizontal Brayton Cycle power conversion system. The design constraint used in sizing the plant is based on a factory modularity principle which allows the plant to be assembled 'Lego' style instead of constructed piece by piece. This principle employs space frames which contain the power conversion system that permits the Lego-like modules to be shipped by truck or train to sites. This paper also describes the research that has been conducted at MIT since 1998 on fuel modeling, silver leakage from coated fuel particles, dynamic simulation, MCNP reactor physics modeling and air ingress analysis

Hinderniserkennung und -verfolgung mit einer PMD-kamera im automobil

Science.gov (United States)

Schamm, Thomas; Vacek, Stefan; Natroshvilli, Koba; Marius Zöllner, J.; Dillmann, Rüdiger

Die Detektion von Hindernissen vor dem Automobil ist eine Hauptanforderung an moderne Fahrerassistenzsysteme (FAS). In dieser Arbeit wird ein System vorgestellt, das mit Hilfe einer PMDKamera (Photomischdetektor) Hindernisse auf der Fahrspur erkennt und deren relevante Parameter bestimmt. Durch die PMD-Kamera werden zunächst 3D-Tiefenbilder der Fahrzeugumwelt generiert. Nach einem initialen Filterprozess werden im Tiefenbild mit Hilfe eines Bereichswachstumsverfahrens Hindernisse gesucht. Zur Stabilisierung des Verfahrens und zur Parameterberechnung wird ein Kaiman Filter eingesetzt. Das Ergebnis ist eine Liste aller Hindernisse im Fahrbereich des Automobils.

Long-lived mitochondrial (Mit) mutants of Caenorhabditis elegans utilize a novel metabolism.

Science.gov (United States)

Butler, Jeffrey A; Ventura, Natascia; Johnson, Thomas E; Rea, Shane L

2010-12-01

The Caenorhabditis elegans mitochondrial (Mit) mutants have disrupted mitochondrial electron transport chain (ETC) functionality, yet, surprisingly, they are long lived. We have previously proposed that Mit mutants supplement their energy needs by exploiting alternate energy production pathways normally used by wild-type animals only when exposed to hypoxic conditions. We have also proposed that longevity in the Mit mutants arises as a property of their new metabolic state. If longevity does arise as a function of metabolic state, we would expect to find a common metabolic signature among these animals. To test these predictions, we established a novel approach monitoring the C. elegans exometabolism as a surrogate marker for internal metabolic events. Using HPLC-ultraviolet-based metabolomics and multivariate analyses, we show that long-lived clk-1(qm30) and isp-1(qm150) Mit mutants have a common metabolic profile that is distinct from that of aerobically cultured wild-type animals and, unexpectedly, wild-type animals cultured under severe oxygen deprivation. Moreover, we show that 2 short-lived mitochondrial ETC mutants, mev-1(kn1) and ucr-2.3(pk732), also share a common metabolic signature that is unique. We show that removal of soluble fumarate reductase unexpectedly increases health span in several genetically defined Mit mutants, identifying at least 1 alternate energy production pathway, malate dismutation, that is operative in these animals. Our study suggests long-lived, genetically specified Mit mutants employ a novel metabolism and that life span may well arise as a function of metabolic state.

MIT - Mighty Steps toward Energy Sustainability

Energy Technology Data Exchange (ETDEWEB)

Robinson, Alastair [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Regnier, Cindy [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Settlemyre, Kevin [Sustainable IQ, Inc., Arlington, MA (United States); Bosnic, Zorana [HOK, San Francisco, CA (United States)

2012-07-01

Massachusetts Institute of Technology (MIT) partnered with the U.S. Department of Energy (DOE) to develop and implement solutions to retrofit existing buildings to reduce energy consumption by at least 30% as part of DOE’s Commercial Building Partnerships (CBP) Program.1 Lawrence Berkeley National Laboratory (LBNL) provided technical expertise in support of this DOE program. MIT is one of the U.S.’s foremost higher education institutions, occupying a campus that is nearly 100 years old, with a building floor area totaling more than 12 million square feet. The CBP project focused on improving the energy performance of two campus buildings, the Ray and Maria Stata Center (RMSC) and the Building W91 (BW91) data center. A key goal of the project was to identify energy saving measures that could be applied to other buildings both within MIT’s portfolio and at other higher education institutions. The CBP retrofits at MIT are projected to reduce energy consumption by approximately 48%, including a reduction of around 72% in RMSC lighting energy and a reduction of approximately 55% in RMSC server room HVAC energy. The energy efficiency measure (EEM) package proposed for the BW91 data center is expected to reduce heating, ventilation, and air-conditioning (HVAC) energy use by 30% to 50%, depending on the final air intake temperature that is established for the server racks. The RMSC, an iconic building designed by Frank Gehry, houses the Computer Science and Artificial Intelligence Laboratory, the Laboratory for Information and Decision Systems, and the Department of Linguistics and Philosophy.

Observing the Sun with Coronado telescopes telescopes

CERN Document Server

Pugh, Philip

2007-01-01

The Sun provides amateur astronomers with one of the few opportunities for daytime astronomy. In order to see the major features of our nearest star, special telescopes that have a very narrow visible bandwidth are essential. The bandwidth has to be as narrow as 1 A- 10-10 m (1 Angstrom) and centred on the absorption line of neutral hydrogen. This makes many major features of the Suna (TM)s chromosphere visible to the observer. Such narrow-band "Fabry-Perot etalon filters" are high technology, and until the introduction of the Coronado range of solar telescopes, were too expensive for amateur use. The entry-level Coronado telescope, the PST (Personal Solar Telescope) costs under 500. Solar prominences (vast columns of plasma, best seen at the edge of the solar disk), filaments, flares, sunspots, plage and active regions are all visible and can be imaged to produce spectacular solar photographs. Philip Pugh has assembled a team of contributors who show just how much solar work can be done with Coronado telesco...

HETDEX tracker control system design and implementation

Science.gov (United States)

Beno, Joseph H.; Hayes, Richard; Leck, Ron; Penney, Charles; Soukup, Ian

2012-09-01

To enable the Hobby-Eberly Telescope Dark Energy Experiment, The University of Texas at Austin Center for Electromechanics and McDonald Observatory developed a precision tracker and control system - an 18,000 kg robot to position a 3,100 kg payload within 10 microns of a desired dynamic track. Performance requirements to meet science needs and safety requirements that emerged from detailed Failure Modes and Effects Analysis resulted in a system of 13 precision controlled actuators and 100 additional analog and digital devices (primarily sensors and safety limit switches). Due to this complexity, demanding accuracy requirements, and stringent safety requirements, two independent control systems were developed. First, a versatile and easily configurable centralized control system that links with modeling and simulation tools during the hardware and software design process was deemed essential for normal operation including motion control. A second, parallel, control system, the Hardware Fault Controller (HFC) provides independent monitoring and fault control through a dedicated microcontroller to force a safe, controlled shutdown of the entire system in the event a fault is detected. Motion controls were developed in a Matlab-Simulink simulation environment, and coupled with dSPACE controller hardware. The dSPACE real-time operating system collects sensor information; motor commands are transmitted over a PROFIBUS network to servo amplifiers and drive motor status is received over the same network. To interface the dSPACE controller directly to absolute Heidenhain sensors with EnDat 2.2 protocol, a custom communication board was developed. This paper covers details of operational control software, the HFC, algorithms, tuning, debugging, testing, and lessons learned.

REVERBERATION MAPPING OF THE INTERMEDIATE-MASS NUCLEAR BLACK HOLE IN SDSS J114008.71+030711.4

International Nuclear Information System (INIS)

Rafter, Stephen E.; Kaspi, Shai; Behar, Ehud; Kollatschny, Wolfram; Zetzl, Matthias

2011-01-01

We present the results of a reverberation mapping (RM) campaign on the black hole (BH) associated with the active galactic nucleus (AGN) in SDSS J114008.71+030711.4 (hereafter GH08). This object is selected from a sample of 19 candidate intermediate-mass BHs (M BH 6 M sun ) found by Greene and Ho in the Sloan Digital Sky Survey. We used the Hobby-Eberly Telescope to obtain 30 spectra over a period of 178 days in an attempt to resolve the reverberation time lag (τ) between the continuum source and the broad-line region (BLR) in order to determine the radius of the BLR (R BLR ) in GH08. We measure τ to be two days with an upper limit of six days. We estimate the AGN luminosity at 5100 Å to be λL 5100 ≈ 1.1 × 10 43 erg s –1 after deconvolution from the host galaxy. The most well-calibrated R BLR –L relation predicts a time lag that is four times larger than what we measure. Using the measured Hβ full width at half-maximum of 703 ± 110 km s –1 and an upper limit for R BLR =6 light days, we find M BH ∼ 5 M sun as an upper limit to the BH virial mass in GH08, which implies super-Eddington accretion. Based on our measured M BH we propose that GH08 may be another candidate to add to the very short list of AGNs with M BH 6 M sun determined using RM.

A LUMINOUS, FAST RISING UV-TRANSIENT DISCOVERED BY ROTSE: A TIDAL DISRUPTION EVENT?

International Nuclear Information System (INIS)

Vinkó, J.; Wheeler, J. C.; Chatzopoulos, E.; Marion, G. H.; Yuan, F.; Akerlof, C.; Quimby, R. M.; Ramirez-Ruiz, E.; Guillochon, J.

2015-01-01

We present follow-up observations of an optical transient (OT) discovered by ROTSE on 2009 January 21. Photometric monitoring was carried out with ROTSE-IIIb in the optical and Swift in the UV up to +70 days after discovery. The light curve showed a fast rise time of ∼10 days followed by a steep decline over the next 60 days, which was much faster than that implied by 56 Ni— 56 Co radioactive decay. The Sloan Digital Sky Survey Data Release 10 database contains a faint, red object at the position of the OT, which appears slightly extended. This and other lines of evidence suggest that the OT is of extragalactic origin, and this faint object is likely the host galaxy. A sequence of optical spectra obtained with the 9.2 m Hobby-Eberly Telescope between +8 and +45 days after discovery revealed a hot, blue continuum with no visible spectral features. A few weak features that appeared after +30 days probably originated from the underlying host. Fitting synthetic templates to the observed spectrum of the host galaxy revealed a redshift of z = 0.19. At this redshift, the peak magnitude of the OT is close to –22.5, similar to the brightest super-luminous supernovae; however, the lack of identifiable spectral features makes the massive stellar death hypothesis less likely. A more plausible explanation appears to be the tidal disruption of a Sun-like star by the central supermassive black hole. We argue that this transient likely belongs to a class of super-Eddington tidal disruption events

STELLAR ACTIVITY AND ITS IMPLICATIONS FOR EXOPLANET DETECTION ON GJ 176

International Nuclear Information System (INIS)

Robertson, Paul; Endl, Michael; Cochran, William D.; MacQueen, Phillip J.; Henry, Gregory W.; Williamson, Michael H.

2015-01-01

We present an in-depth analysis of stellar activity and its effects on radial velocity (RV) for the M2 dwarf GJ 176 based on spectra taken over 10 yr from the High Resolution Spectrograph on the Hobby-Eberly Telescope. These data are supplemented with spectra from previous observations with the HIRES and HARPS spectrographs, and V- and R-band photometry taken over six years at the Dyer and Fairborn observatories. Previous studies of GJ 176 revealed a super-Earth exoplanet in an 8.8-day orbit. However, the velocities of this star are also known to be contaminated by activity, particularly at the 39-day stellar rotation period. We have examined the magnetic activity of GJ 176 using the sodium I D lines, which have been shown to be a sensitive activity tracer in cool stars. In addition to rotational modulation, we see evidence of a long-term trend in our Na I D index, which may be part of a long-period activity cycle. The sodium index is well correlated with our RVs, and we show that this activity trend drives a corresponding slope in RV. Interestingly, the rotation signal remains in phase in photometry, but not in the spectral activity indicators. We interpret this phenomenon as the result of one or more large spot complexes or active regions which dominate the photometric variability, while the spectral indices are driven by the overall magnetic activity across the stellar surface. In light of these results, we discuss the potential for correcting activity signals in the RVs of M dwarfs

Netball team members, but not hobby group members, distinguish team characteristics from group characteristics.

Science.gov (United States)

Stillman, Jennifer A; Fletcher, Richard B; Carr, Stuart C

2007-04-01

Research on groups is often applied to sport teams, and research on teams is often applied to groups. This study investigates the extent to which individuals have distinct schemas for groups and teams. A list of team and group characteristics was generated from 250 individuals, for use in this and related research. Questions about teams versus groups carry an a priori implication that differences exist; therefore, list items were presented to new participants and were analyzed using signal detection theory, which can accommodate a finding of no detectable difference between a nominated category and similar items. Participants were 30 members from each of the following: netball teams, the general public, and hobby groups. Analysis revealed few features that set groups apart from teams; however, teams were perceived as more structured and demanding, requiring commitment and effort toward shared goals. Team and group characteristics were more clearly defined to team members than they were to other participant groups. The research has implications for coaches and practitioners.

MITS Data Acquisition Subsystem Acceptance Test procedure

International Nuclear Information System (INIS)

Allison, R.

1980-01-01

This is an acceptance procedure for the Data Acquisition Subsystem of the Machine Interface Test System (MITS). Prerequisites, requirements, and detailed step-by-step instruction are presented for inspecting and performance testing the subsystem

Analyse von Kunststoffadditiven mittels Laserablation gekoppelt mit induktiv gekoppelter Plasma Massenspektrometrie

OpenAIRE

Börno, Fabian

2016-01-01

Die Laserablation gekoppelt mit der Massenspektrometrie mit induktiv gekoppeltem Plasma ist eine vielversprechende direkte Feststofftechnik, die sich jedoch bei der Analyse von Kunststoffen wegen des Mangels an matrixangepassten zertifizierten Referenzmaterialien nicht durchsetzen konnte. Vorherige Arbeiten belegen polymerabhängige Abtragsraten. Das oft als interner Standard verwendete Intensitätssignal des Kohlenstoffisotopes 13C zur Korrektur dieser Unterschiede wird in der Literatur kritis...

Untersuchungen zur Farbreaktion von Amilorid, Chlorhexidin und Proguanil mit Hypobromit

OpenAIRE

Huth, Silke

2004-01-01

Bei der Reaktion von Amiloridhydrochlorid (1· HCl) mit Brom in alkalischer Lösung wird ein gelbbraunes Dehydrierungsprodukt erhalten, daß als 3-(3-Amino-1,2,4-oxadiazol-5-yl)-5-chlor-2,6-pyrazindiamin (6) identifiziert werden konnte. Durch Vergleich von Massen- und NMR-Spektren der Verbindung 6 mit Spektren von 1· HCl und Referenzsubstanzen I-III konnte auf die verbindung 6 geschlossen werden. Die Struktur wurde durch eine Röntgenstrukturanalyse abgesichert. Erhitzen von Amiloridhydrochlorid ...

Islam, Migration und Integration: Konflikte jugendlicher Migranten mit islamischem Hintergrund

Directory of Open Access Journals (Sweden)

Ilhan Kizilhan

2008-04-01

Full Text Available Der Islam mit seinen verschiedenen Verhaltensweisen und Verboten spielt direkt oder indirekt immer noch eine wichtige Rolle im alltäglichen Leben vieler Migranten. Religiöse Vorschriften zeichnen sich dadurch aus, dass ihrer Achtung nicht juristisch, sondern durch sozialen Druck Nachdruck verliehen wird (Verwandtschaft, religiöse Lehrer, islamische Gemeinde, religiöse Vereine etc. und dass ihre Missachtung mit Folgen in Form von Ausgrenzung, Missachtung und Diskriminierung einhergeht. Die kulturellen Vorstellungen der ersten Generation unterscheiden sich auf Grund der unterschiedlichen Biografien von denen der zweiten und dritten durch den Grad der Verwurzelung in der kulturellen Identität und der Verbundenheit mit traditionellen Wertvorstellungen. Fehlende Integrationskonzepte, Ausgrenzung im Migrationsland auf der einen und weltweite staatliche und halbstaatliche Konflikte im Namen des Islams bis hin zum Terrorismus auf der anderen Seite haben einen erheblichen Einfluss auf den Integrationsgrad von jugendlichen Migranten im Aufnahmeland.

Scratch that: MIT's Mitchel Resnick Says Kids Should Do It for Themselves

Science.gov (United States)

Traylor, Scott

2008-01-01

Mitchel Resnick is a researcher, inventor, and professor at MIT's Media Laboratory in Cambridge, MA, and the founder of the Lifelong Kindergarten Group at MIT. He is the lead innovator behind many cutting-edge learning technologies and projects for children, including the Computer Clubhouse, PicoCrickets, and the wildly successful consumer…

Der Entwurf einer Musterwohnung für ältere Menschen mit Demenz

NARCIS (Netherlands)

Joost van Hoof

2014-01-01

Einführung Ältere Menschen mit Demenz brauchen Wohnungen, die sowohl altersgemäß ausgestattet sind als auch die erforderliche Pflege im Haus anbieten. Traditionelle Änderungen und entsprechende Technologien bieten in erster Linie Lösungen für Personen mit eingeschränkter Mobilität. Dies bedeutet,

MIT-Skywalker: Evaluating comfort of bicycle/saddle seat.

Science.gov (United States)

Goncalves, Rogerio S; Hamilton, Taya; Daher, Ali R; Hirai, Hiroaki; Krebs, Hermano I

2017-07-01

The MIT-Skywalker is a robotic device developed for the rehabilitation of gait and balance after a neurological injury. This device has been designed based on the concept of a passive walker and provides three distinct training modes: discrete movement, rhythmic movement, and balance training. In this paper, we present our efforts to evaluate the comfort of a bicycle/saddle seat design for the system's novel actuated body weight support device. We employed different bicycle and saddle seats and evaluated comfort using objective and subjective measures. Here we will summarize the results obtained from a study of fifteen healthy subjects and one stroke patient that led to the selection of a saddle seat design for the MIT-Skywalker.

Assessing International Product Design and Development Graduate Courses: The MIT-Portugal Program

Science.gov (United States)

Dori, Yehudit Judy; Silva, Arlindo

2010-01-01

The Product Design and Development (PDD) course is part of the graduate curriculum in the Engineering Design and Advanced Manufacturing (EDAM) study in the MIT-Portugal Program. The research participants included about 110 students from MIT, EDAM, and two universities in Portugal, Instituto Superior Técnico-Universidade Técnica de Lisboa (IST) and…

MITS instrumentation error analysis report

International Nuclear Information System (INIS)

Nelson, D.W.; Hillon, D.D.

1980-01-01

The MITS (Machine Interface Test System) installation consists of three types of process monitoring and control instrumentation: flow, pressure, and temperature. An effort has been made to assess the various instruments used and assign a value to the accuracy that can be expected. Efforts were also made to analyze the calibration and installation procedures to be used and determine how these might effect the system accuracy

MIT miniaturized disk bend test

International Nuclear Information System (INIS)

Harling, O.K.; Lee, M.; Sohn, D.S.; Kohse, G.; Lau, C.W.

1983-01-01

A miniaturized disk bend test (MDBT) using transmission electron microscopy specimens for the determination of various mechanical properties is being developed at MIT. Recent progress in obtaining strengths and ductilities of highly irradiated metal alloys is reviewed. Other mechanical properties can also be obtained using the MDBT approach. Progress in fatigue testing and in determination of the ductile-to-brittle transition temperature is reviewed briefly. 11 figures

Vitex-agnus-castus-Extrakt (Ze 440 zur Symptombehandlung bei Frauen mit menstruellen Zyklusstörungen

Directory of Open Access Journals (Sweden)

Eltbogen R

2015-01-01

Full Text Available Ziel: Diese nichtinterventionelle Beobachtungsstudie (NIS wurde von Schweizer Gynäkologen und Allgemeinmedizinern im Rahmen der üblichen ärztlichen Grundversorgung durchgeführt. Das Ziel der NIS war es, die Wirksamkeit und Sicherheit von Vitex-agnus-castus-(VAC Extrakt (Ze 440: premens, Zeller Medical AG, Romanshorn, Schweiz bei Frauen, die unter menstruellen Zyklusstörungen wie Polymenorrhö, Oligomenorrhö oder Amenorrhö litten, zu untersuchen. Methode: Insgesamt 211 Patientinnen nahmen an dieser NIS teil. Symptome, die mit menstruellen Zyklusstörungen („menstrual cycle irregularities“ [MCIs] und der Menstruationsblutung in Verbindung stehen, wurden bei einer Erstuntersuchung („baseline visit“ [BV] und einer Kontrolluntersuchung („follow-up visit“ [FV] nach Behandlung mit VAC-Extrakt über einen Zeitraum von 3 aufeinanderfolgenden Menstruationszyklen beurteilt. Ergebnisse: Der Anteil der Patientinnen, bei denen eine Beschwerdefreiheit oder eine Besserung der MCIs (insgesamt und spezifischer Beschwerdebilder wie Polymenorrhö, Oligomenorrhö und Amenorrhö erzielt werden konnte, lag bei der FV bei 79–85 %. Bei Symptomen im Zusammenhang mit der Menstruationsblutung wie Dysmenorrhö, Zwischenblutungen, Hypermenorrhö, Menometrorrhagie, Ovulationsblutung, präoder postmenstrueller Blutung betrug der Anteil der Patientinnen, bei denen ein Rückgang oder eine Besserung festgestellt wurde, bei der FV zwischen 60 und 88 %. Von 53 Patientinnen, die bei der BV von einem unerfüllten Kinderwunsch berichteten, wurden 12 Frauen (23 % während der Behandlung mit VAC-Extrakt schwanger. Bei der FV waren 91 % der Ärzte und 92 % der Patientinnen mit den erzielten Behandlungsergebnissen „zufrieden“ oder „sehr zufrieden“ und 80 % der Patientinnen bestätigten, dass sie gerne mit der Behandlung mit VAC-Extrakt fortfahren wollen. Fazit: Diese Beobachtungsstudie im Bereich der ärztlichen Grundversorgung ergab, dass die Behandlung mit VAC

Interaktion mit RFID Ausleih- und Rückgabeautomaten

DEFF Research Database (Denmark)

Greifeneder, Elke; Heyroth, Melanie; Klingbeil, Karin

2011-01-01

Der Artikel untersucht mittels Beobachtung die Interaktion zwischen RFID-Ausleih- und Rückgabeautomaten sowie Bibliotheksbenutzern in vier deutschen Bibliotheken. Die Ergebnisse belegen, dass die Interaktion grundsätzlich funktioniert. Die Benutzer zeigten Gelassenheit und Routine im Umgang mit den...

From x-ray telescopes to neutron scattering: Using axisymmetric mirrors to focus a neutron beam

International Nuclear Information System (INIS)

Khaykovich, B.; Gubarev, M.V.; Bagdasarova, Y.; Ramsey, B.D.; Moncton, D.E.

2011-01-01

We demonstrate neutron beam focusing by axisymmetric mirror systems based on a pair of mirrors consisting of a confocal ellipsoid and hyperboloid. Such a system, known as a Wolter mirror configuration, is commonly used in X-ray telescopes. The axisymmetric Wolter geometry allows nesting of several mirror pairs to increase collection efficiency. We implemented a system containing four nested Ni mirror pairs, which was tested by the focusing of a polychromatic neutron beam at the MIT Reactor. In addition, we have carried out extensive ray-tracing simulations of the mirrors and their performance in different situations. The major advantages of the Wolter mirrors are nesting for large angular collection and aberration-free performance. We discuss how these advantages can be utilized to benefit various neutron scattering methods, such as imaging, SANS, and time-of-flight spectroscopy.

Knocking down mitochondrial iron transporter (MIT) reprograms primary and secondary metabolism in rice plants.

Science.gov (United States)

Vigani, Gianpiero; Bashir, Khurram; Ishimaru, Yasuhiro; Lehmann, Martin; Casiraghi, Fabio Marco; Nakanishi, Hiromi; Seki, Motoaki; Geigenberger, Peter; Zocchi, Graziano; Nishizawa, Naoko K

2016-03-01

Iron (Fe) is an essential micronutrient for plant growth and development, and its reduced bioavailability strongly impairs mitochondrial functionality. In this work, the metabolic adjustment in the rice (Oryza sativa) mitochondrial Fe transporter knockdown mutant (mit-2) was analysed. Biochemical characterization of purified mitochondria from rice roots showed alteration in the respiratory chain of mit-2 compared with wild-type (WT) plants. In particular, proteins belonging to the type II alternative NAD(P)H dehydrogenases accumulated strongly in mit-2 plants, indicating that alternative pathways were activated to keep the respiratory chain working. Additionally, large-scale changes in the transcriptome and metabolome were observed in mit-2 rice plants. In particular, a strong alteration (up-/down-regulation) in the expression of genes encoding enzymes of both primary and secondary metabolism was found in mutant plants. This was reflected by changes in the metabolic profiles in both roots and shoots of mit-2 plants. Significant alterations in the levels of amino acids belonging to the aspartic acid-related pathways (aspartic acid, lysine, and threonine in roots, and aspartic acid and ornithine in shoots) were found that are strictly connected to the Krebs cycle. Furthermore, some metabolites (e.g. pyruvic acid, fumaric acid, ornithine, and oligosaccharides of the raffinose family) accumulated only in the shoot of mit-2 plants, indicating possible hypoxic responses. These findings suggest that the induction of local Fe deficiency in the mitochondrial compartment of mit-2 plants differentially affects the transcript as well as the metabolic profiles in root and shoot tissues. © The Author 2015. Published by Oxford University Press on behalf of the Society for Experimental Biology.

Ernährungszustand bei Patienten mit chronisch entzündlichen Darmerkrankungen

OpenAIRE

Blunk, Christine

2009-01-01

Zahlreiche internationale Studien konnten den negativen Einfluss einer bestehenden Malnutrition auf den Verlauf einer Erkrankung belegen. Dies gilt insbesondere für Patienten mit chronisch entzündlichen Darmerkrankungen wie Morbus Crohn und Colitis ulcerosa, die wie klinische Studien gezeigt haben besonders häufig unter einer Malnutrition leiden. In der vorliegenden Studie wurde der Ernährungszustand von 127 Patienten mit chronisch entzündlichen Darmerkrankungen anhand verschiedener etabli...

The DAG project, a 4m class telescope: the telescope main structure performances

Science.gov (United States)

Marchiori, G.; Busatta, A.; Ghedin, L.; Marcuzzi, E.; Manfrin, C.; Battistel, C.; Pirnay, O.; Flebus, Carlo; Yeşilyaprak, C.; Keskin, O.; Yerli, S.

2016-07-01

Dogu Anatolu Gözlemevi (DAG-Eastern Anatolia Observatory) Project is a 4m class optical, near-infrared Telescope and suitable enclosure which will be located at an altitude of 3.170m in Erzurum, Turkey. The DAG telescope is a project fully funded by Turkish Ministry of Development and the Atatürk University of Astrophysics Research Telescope - ATASAM. The Project is being developed by the Belgian company AMOS (project leader), which is also the optics supplier and EIE GROUP, the Telescope Main Structure supplier and responsible for the final site integration. The design of the Telescope Main Structure fits in the EIE TBO Program which aims at developing a Dome/Telescope systemic optimization process for both performances and competitive costs based on previous project commitments like NTT, VLT, VST and ASTRI. The optical Configuration of the DAG Telescope is a Ritchey-Chretien with two Nasmyth foci and a 4m primary thin mirror controlled in shape and position by an Active Optic System. The main characteristics of the Telescope Main Structure are an Altitude-Azimuth light and rigid structure system with Direct Drive Systems for both axis, AZ Hydrostatic Bearing System and Altitude standard bearing system; both axes are equipped with Tape Encoder System. An innovative Control System characterizes the telescope performance.

[Postoperative adjuvante Therapie mit einem Mistelextrakt (Viscum album ssp. album) bei Hündinnen mit Mammatumoren].

Science.gov (United States)

Biegel, Ulrike; Stratmann, Nina; Knauf, Yvonne; Ruess, Katja; Reif, Marcus; Wehrend, Axel

2017-01-01

Hintergrund: Canine Mammatumoren (CMT) sind wegen ihrer Häufigkeit und hohen Malignitätsrate eine Herausforderung für die Veterinärmedizin. Bisher ist noch keine postoperative adjuvante Therapie als wirksamer Standard etabliert und in den nächsten Jahren wohl auch nicht zu erwarten. Zusätzlich ist die Frage nach der Verträglichkeit einer adjuvanten Therapie mit Erhaltung oder Verbesserung der Lebensqualität (LQ) wichtig. Die Therapie mit Mistelextrakten (Viscum album L.; VAE) ist in der Humanonkologie nach adjuvanter Tumorbasistherapie (Chemotherapie und Bestrahlung) eine sehr häufig verwendete, zusätzliche adjuvante Behandlungsmethode. Auch bei verschiedenen Tierarten werden inzwischen Mistelpräparate in der Onkologie erfolgreich angewendet. Methoden: Überprüfung von Wirkung und Nutzen einer postoperativen, adjuvanten Misteltherapie beim CMT sowie Erfassung der LQ unter der VAE-Behandlung. Ausgewertet wurden 56 Hündinnen mit Mammaadenokarzinom, 33 ausschließlich operierte Kontrolltiere und 23 operierte Tiere, die adjuvant VAE erhielten. Ergebnisse: Die mediane Überlebenszeit (MST) aller Tiere (n = 56) betrug 32 Monate (Interquartilbereich 13-51 Monate). Im deskriptiven Vergleich der Überlebenszeiten (ST) nach Kaplan-Meier waren nach 12, 24, 36 bzw. 48 Monaten noch 24, 20, 15 bzw. 5 Hündinnen (entsprechend 72,7%, 60,6%, 45,1%, 12,4%) der Kontrollgruppe sowie 19, 14, 11 und 1 Hündin (82,6%, 60,9%, 47,8%, 4,3%) der VAE-Gruppe am Leben. Die VAE-Therapie führte zu einem geringeren Gesamtversterberisiko, das statistisch nicht signifikant war (Hazard Ratio (HR) 0,530, 95%-Konfidenzintervall (KI) 0,222-1,262; p = 0,15). Tendenziell (p = 0,07) zeigte sich eine Verringerung des tumorbedingten Sterberisikos auf 25% (HR 0,251, 95%-KI 0,056-1,122). Schlussfolgerungen: Es kann eine Tendenz zur Senkung des tumorbedingten Sterberisikos der VAE-Gruppe bei guter Verträglichkeit der Therapie angenommen werden. Die LQ der Tiere blieb über die gesamte

MITS Feed and Withdrawal Subsystem: operating procedures

International Nuclear Information System (INIS)

Brown, W.S.

1980-01-01

This procedure details the steps involved in filling two of the four MITS (Machine Interface Test System) Feed and Withdrawal subsystem main traps and the Sample/Inventory Make-up Pipette with uranium hexafluoride from the ''AS RECEIVED'' UF 6 supply

MIT gets good marks for fighting gender discrimination

Science.gov (United States)

Gwynne, Peter

2011-05-01

The Massachusetts Institute of Technology (MIT) has made "significant progress" in increasing the number of female faculty members, with their numbers in science and engineering almost doubling over the last decade.

Binding of Substrates to the Central Pore of the Vps4 ATPase Is Autoinhibited by the Microtubule Interacting and Trafficking (MIT) Domain and Activated by MIT Interacting Motifs (MIMs).

Science.gov (United States)

Han, Han; Monroe, Nicole; Votteler, Jörg; Shakya, Binita; Sundquist, Wesley I; Hill, Christopher P

2015-05-22

The endosomal sorting complexes required for transport (ESCRT) pathway drives reverse topology membrane fission events within multiple cellular pathways, including cytokinesis, multivesicular body biogenesis, repair of the plasma membrane, nuclear membrane vesicle formation, and HIV budding. The AAA ATPase Vps4 is recruited to membrane necks shortly before fission, where it catalyzes disassembly of the ESCRT-III lattice. The N-terminal Vps4 microtubule-interacting and trafficking (MIT) domains initially bind the C-terminal MIT-interacting motifs (MIMs) of ESCRT-III subunits, but it is unclear how the enzyme then remodels these substrates in response to ATP hydrolysis. Here, we report quantitative binding studies that demonstrate that residues from helix 5 of the Vps2p subunit of ESCRT-III bind to the central pore of an asymmetric Vps4p hexamer in a manner that is dependent upon the presence of flexible nucleotide analogs that can mimic multiple states in the ATP hydrolysis cycle. We also find that substrate engagement is autoinhibited by the Vps4p MIT domain and that this inhibition is relieved by binding of either Type 1 or Type 2 MIM elements, which bind the Vps4p MIT domain through different interfaces. These observations support the model that Vps4 substrates are initially recruited by an MIM-MIT interaction that activates the Vps4 central pore to engage substrates and generate force, thereby triggering ESCRT-III disassembly. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

Binding of Substrates to the Central Pore of the Vps4 ATPase Is Autoinhibited by the Microtubule Interacting and Trafficking (MIT) Domain and Activated by MIT Interacting Motifs (MIMs)*

Science.gov (United States)

Han, Han; Monroe, Nicole; Votteler, Jörg; Shakya, Binita; Sundquist, Wesley I.; Hill, Christopher P.

2015-01-01

The endosomal sorting complexes required for transport (ESCRT) pathway drives reverse topology membrane fission events within multiple cellular pathways, including cytokinesis, multivesicular body biogenesis, repair of the plasma membrane, nuclear membrane vesicle formation, and HIV budding. The AAA ATPase Vps4 is recruited to membrane necks shortly before fission, where it catalyzes disassembly of the ESCRT-III lattice. The N-terminal Vps4 microtubule-interacting and trafficking (MIT) domains initially bind the C-terminal MIT-interacting motifs (MIMs) of ESCRT-III subunits, but it is unclear how the enzyme then remodels these substrates in response to ATP hydrolysis. Here, we report quantitative binding studies that demonstrate that residues from helix 5 of the Vps2p subunit of ESCRT-III bind to the central pore of an asymmetric Vps4p hexamer in a manner that is dependent upon the presence of flexible nucleotide analogs that can mimic multiple states in the ATP hydrolysis cycle. We also find that substrate engagement is autoinhibited by the Vps4p MIT domain and that this inhibition is relieved by binding of either Type 1 or Type 2 MIM elements, which bind the Vps4p MIT domain through different interfaces. These observations support the model that Vps4 substrates are initially recruited by an MIM-MIT interaction that activates the Vps4 central pore to engage substrates and generate force, thereby triggering ESCRT-III disassembly. PMID:25833946

Possibilities of transport with monorails; Moeglichkeiten des Transports mit Einschienenhaengebahnen

Energy Technology Data Exchange (ETDEWEB)

Bolz, P. [Deutsche Montan Technologie GmbH, Bochum (Germany)

2001-08-02

The safety limits of transport by monorails were determined within the framework of a test project. The safety-related components of the system, in particular the rail system with its suspensions and the drive and braking system, were investigated for normal and heavy load transport. In addition to operational measurements for actual stressing of the components tests were conducted on test benches to determine the dynamic strength. The concept of a new forward-looking monorail system with greater safety was subsequently developed with the aid of the results obtained. The compatibility with the previous components was ensured. Compared to the determined load capacity limits a development requirement for monorail suspension anchor bolts, diesel- and battery-operated trolleys as well as braking trolleys for ropeways were derived. The other components are already adequately dimensioned. (orig.) [German] Im Rahmen eines Untersuchungsvorhabens wurden die sicherheitlichen Grenzen des Transports mit EHB ermittelt. Die sicherheitsrelevanten Bauteile des Systems, insbesondere das Schienensystem mit seinen Aufhaengungen sowie das Antriebs- und Bremssystem, wurden fuer den Normal- und den Schwerlasttransport untersucht. Neben Betriebsmessungen zur tatsaechlichen Beanspruchung der Bauteile erfolgten Pruefstandsuntersuchungen zur dynamischen Festigkeit. Mit Hilfe der gewonnenen Ergebnisse wurde anschliessend das Konzept fuer ein neues, zukunftsorientiertes EHB-System mit erhoehter Sicherheit erarbeitet. Die Kompatibilitaet zu den bisherigen Bauteilen wurde dabei gewaehrleistet. Im Vergleich zu den ermittelten Belastbarkeitsgrenzen wurde daraus ein Entwicklungsbedarf bei EHB-Aufhaengeankern, Diesel- und Batteriekatzen sowie Bremskatzen fuer Seilbahnen abgeleitet. Die uebrigen Bauteile sind bereits jetzt ausreichend bemessen. (orig.)

MIT professor wins major international math prize

CERN Multimedia

Allen, S

2004-01-01

Mathematicians Isadore Singer of MIT and Sir Michael Francis Atiyah of the University of Edinburgh will share an $875,000 award as winners of the second Abel Prize, which some hope will come to be seen as a Nobel Prize for math.

THE HOT-JUPITER KEPLER-17b: DISCOVERY, OBLIQUITY FROM STROBOSCOPIC STARSPOTS, AND ATMOSPHERIC CHARACTERIZATION

Energy Technology Data Exchange (ETDEWEB)

Desert, Jean-Michel; Charbonneau, David; Ballard, Sarah; Carter, Joshua A.; Quinn, Samuel N.; Fressin, Francois; Latham, David W.; Torres, Guillermo [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Demory, Brice-Olivier [Massachusetts Institute of Technology, Cambridge, MA 02159 (United States); Fortney, Jonathan J. [Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA 95064 (United States); Cochran, William D.; Endl, Michael [Department of Astronomy, University of Texas, Austin (United States); Isaacson, Howard T.; Knutson, Heather A. [Department of Astronomy, University of California, Berkeley, CA 94720-3411 (United States); Buchhave, Lars A. [Neils Bohr Institute, University of Copenhagen, DK-2100 Denmark (Denmark); Bryson, Stephen T.; Rowe, Jason F.; Borucki, William J. [NASA Ames Research Center, Moffett Field, CA 94035 (United States); Batalha, Natalie M. [San Jose State University, San Jose, CA 95192 (United States); Brown, Timothy M., E-mail: jdesert@cfa.harvard.edu [Las Cumbres Observatory Global Telescope, Goleta, CA 93117 (United States); and others

2011-11-01

This paper reports the discovery and characterization of the transiting hot giant exoplanet Kepler-17b. The planet has an orbital period of 1.486 days, and radial velocity measurements from the Hobby-Eberly Telescope show a Doppler signal of 419.5{sup +13.3}{sub -15.6} m s{sup -1}. From a transit-based estimate of the host star's mean density, combined with an estimate of the stellar effective temperature T{sub eff} = 5630 {+-} 100 from high-resolution spectra, we infer a stellar host mass of 1.06 {+-} 0.07 M{sub Sun} and a stellar radius of 1.02 {+-} 0.03 R{sub Sun }. We estimate the planet mass and radius to be M{sub P} = 2.45 {+-} 0.11 M{sub J} and R{sub P} = 1.31 {+-} 0.02 R{sub J}. The host star is active, with dark spots that are frequently occulted by the planet. The continuous monitoring of the star reveals a stellar rotation period of 11.89 days, eight times the planet's orbital period; this period ratio produces stroboscopic effects on the occulted starspots. The temporal pattern of these spot-crossing events shows that the planet's orbit is prograde and the star's obliquity is smaller than 15 Degree-Sign . We detected planetary occultations of Kepler-17b with both the Kepler and Spitzer Space Telescopes. We use these observations to constrain the eccentricity, e, and find that it is consistent with a circular orbit (e < 0.011). The brightness temperatures of the planet's infrared bandpasses are T{sub 3.6{mu}m} = 1880 {+-} 100 K and T{sub 4.5{mu}m} = 1770 {+-} 150 K. We measure the optical geometric albedo A{sub g} in the Kepler bandpass and find A{sub g} = 0.10 {+-} 0.02. The observations are best described by atmospheric models for which most of the incident energy is re-radiated away from the day side.

A Versatile Technique to Enable Sub-milli-Kelvin Instrument Stability for Precise Radial Velocity Measurements: Tests with the Habitable-zone Planet Finder

Science.gov (United States)

Stefansson, Gudmundur; Hearty, Frederick; Robertson, Paul; Mahadevan, Suvrath; Anderson, Tyler; Levi, Eric; Bender, Chad; Nelson, Matthew; Monson, Andrew; Blank, Basil; Halverson, Samuel; Henderson, Chuck; Ramsey, Lawrence; Roy, Arpita; Schwab, Christian; Terrien, Ryan

2016-12-01

Insufficient instrument thermomechanical stability is one of the many roadblocks for achieving 10 cm s-1 Doppler radial velocity precision, the precision needed to detect Earth-twins orbiting solar-type stars. Highly temperature and pressure stabilized spectrographs allow us to better calibrate out instrumental drifts, thereby helping in distinguishing instrumental noise from astrophysical stellar signals. We present the design and performance of the Environmental Control System (ECS) for the Habitable-zone Planet Finder (HPF), a high-resolution (R = 50,000) fiber-fed near-infrared (NIR) spectrograph for the 10 {{m}} Hobby-Eberly Telescope at McDonald Observatory. HPF will operate at 180 {{K}}, driven by the choice of an H2RG NIR detector array with a 1.7 μ {{m}} cutoff. This ECS has demonstrated 0.6 {mK} rms stability over 15 days at both 180 and 300 {{K}}, and maintained high-quality vacuum (\\lt {10}-7 {Torr}) over months, during long-term stability tests conducted without a planned passive thermal enclosure surrounding the vacuum chamber. This control scheme is versatile and can be applied as a blueprint to stabilize future NIR and optical high-precision Doppler instruments over a wide temperature range from ˜77 {{K}} to elevated room temperatures. A similar ECS is being implemented to stabilize NEID, the NASA/NSF NN-EXPLORE spectrograph for the 3.5 {{m}} WIYN telescope at Kitt Peak, operating at 300 {{K}}. A [full SolidWorks 3D-CAD model] and a comprehensive parts list of the HPF ECS are included with this manuscript to facilitate the adaptation of this versatile environmental control scheme in the broader astronomical community. Certain commercial equipment, instruments, or materials are identified in this paper in order to specify the experimental procedure adequately. Such identification is not intended to imply recommendation or endorsement by the National Institute of Standards and Technology, nor is it intended to imply that the materials or equipment

THE DISCOVERY OF HD 37605c AND A DISPOSITIVE NULL DETECTION OF TRANSITS OF HD 37605b

International Nuclear Information System (INIS)

Wang, Sharon Xuesong; Wright, Jason T.; Mahadevan, Suvrath; Cochran, William; Endl, Michael; MacQueen, Phillip J.; Kane, Stephen R.; Von Braun, Kaspar; Henry, Gregory W.; Payne, Matthew J.; Ford, Eric B.; Valenti, Jeff A.; Antoci, Victoria; Dragomir, Diana; Matthews, Jaymie M.; Howard, Andrew W.; Marcy, Geoffrey W.; Isaacson, Howard

2012-01-01

We report the radial velocity discovery of a second planetary mass companion to the K0 V star HD 37605, which was already known to host an eccentric, P ∼ 55 days Jovian planet, HD 37605b. This second planet, HD 37605c, has a period of ∼7.5 years with a low eccentricity and an Msin i of ∼3.4 M Jup . Our discovery was made with the nearly 8 years of radial velocity follow-up at the Hobby-Eberly Telescope and Keck Observatory, including observations made as part of the Transit Ephemeris Refinement and Monitoring Survey effort to provide precise ephemerides to long-period planets for transit follow-up. With a total of 137 radial velocity observations covering almost 8 years, we provide a good orbital solution of the HD 37605 system, and a precise transit ephemeris for HD 37605b. Our dynamic analysis reveals very minimal planet-planet interaction and an insignificant transit time variation. Using the predicted ephemeris, we performed a transit search for HD 37605b with the photometric data taken by the T12 0.8 m Automatic Photoelectric Telescope (APT) and the MOST satellite. Though the APT photometry did not capture the transit window, it characterized the stellar activity of HD 37605, which is consistent of it being an old, inactive star, with a tentative rotation period of 57.67 days. The MOST photometry enabled us to report a dispositive null detection of a non-grazing transit for this planet. Within the predicted transit window, we exclude an edge-on predicted depth of 1.9% at the >>10σ level, and exclude any transit with an impact parameter b > 0.951 at greater than 5σ. We present the BOOTTRAN package for calculating Keplerian orbital parameter uncertainties via bootstrapping. We made a comparison and found consistency between our orbital fit parameters calculated by the RVLIN package and error bars by BOOTTRAN with those produced by a Bayesian analysis using MCMC.

The large binocular telescope.

Science.gov (United States)

Hill, John M

2010-06-01

The Large Binocular Telescope (LBT) Observatory is a collaboration among institutions in Arizona, Germany, Italy, Indiana, Minnesota, Ohio, and Virginia. The telescope on Mount Graham in Southeastern Arizona uses two 8.4 m diameter primary mirrors mounted side by side. A unique feature of the LBT is that the light from the two Gregorian telescope sides can be combined to produce phased-array imaging of an extended field. This cophased imaging along with adaptive optics gives the telescope the diffraction-limited resolution of a 22.65 m aperture and a collecting area equivalent to an 11.8 m circular aperture. This paper describes the design, construction, and commissioning of this unique telescope. We report some sample astronomical results with the prime focus cameras. We comment on some of the technical challenges and solutions. The telescope uses two F/15 adaptive secondaries to correct atmospheric turbulence. The first of these adaptive mirrors has completed final system testing in Firenze, Italy, and is planned to be at the telescope by Spring 2010.

Prospect of mechanical engineering. Report from MIT; Kikai kogaku no atarashii tenkai. MIT kara no hokoku

Energy Technology Data Exchange (ETDEWEB)

Asada, H [Massachusetts Inst. of Technology, Cambridge, MA (United States)

1996-01-05

The author of this article is a professor of Department of Mechanical Engineering of Massachusetts Institute of Technology (MIT) and the director general of Laboratory for Information Systems and Technology of the institute. At Department of Mechanical Engineering of Engineering Faculty of world-famous MIT, Laboratory for Information Systems and Technology was established in 1994 and in the same year, the curricula of the department were greatly revised after 30 years for its enforcement from the new semester starting from September, 1995. These two occasions are suggestive for guessing the future of mechanical engineering, hence its aim and meaning are introduced. Department of Mechanical Engineering aims to bring up system integrators who can consolidate systems based on wide-ranged knowledge, and its basic subjects are divided into 4 subjects namely dynamics and control, heat and fluid, system engineering and control, and design and production, and it has been decided that each of them is taught in equal weight and in parallel. Also as a new study field in the above Department of Mechanical Engineering, nanotechnology and artificial intelligence, and high-technological aircraft and networks are shown as examples.

Nanomedical strategy to prolong survival period, heighten cure rate, and lower systemic toxicity of S180 mice treated with MTX/MIT.

Science.gov (United States)

Song, Ning; Zhao, Ming; Wang, Yuji; Hu, Xi; Wu, Jianhui; Jiang, Xueyun; Li, Shan; Cui, Chunying; Peng, Shiqi

2016-01-01

In spite of the usual combination form of methotrexate (MTX)/mitoxantrone (MIT) and various complex combination regimens of MTX/MIT with other anticancer drugs, the survival period, cure rate, and systemic toxicity still need to be improved. For this purpose, a nanostructured amino group-modified mesoporous silica nanoparticles (MSNN)-MTX/MIT was designed. In the preparation, the surface of mesoporous silica nanoparticles (MSNs) was modified with amino groups to form MSNN. The covalent modification of the amino groups on the surface of MSNN with MTX resulted in MSNN-MTX. The loading of MIT into the surface pores of MSNN-MTX produced nanostructured MSNN-MTX/MIT. Compared with the usual combination form (MTX/MIT), nanostructured MSNN-MTX/MIT increased the survival period greatly, heightened the cure rate to a great extent, and lowered the systemic toxicity of the treated S180 mice, significantly. These superior in vivo properties of nanostructured MSNN-MTX/MIT over the usual combination form (MTX/MIT) were correlated with the former selectively releasing MTX and MIT in tumor tissue and inside cancer cells in vitro. The chemical structure and the nanostructure of MSNN-MTX/MIT were characterized using infrared and differential scanning calorimeter spectra as well as transmission electron microscope images, respectively.

Behandlung des chronischen Tinnitus mit repetitiver transkranieller Magnetstimulation

OpenAIRE

Kleinjung, T

2012-01-01

Tinnitus ist eine Funktionsstörung des Hörsystems, die von verschiedenen Strukturen und Ebenen ausgehen kann. Tinnitus geht mit neuroplastischen Veränderungen im zentralen auditorischen System einher. Existenz eines „Tinnitus-Netzwerkes“.

Are the N and Δ deformed MIT bags

International Nuclear Information System (INIS)

Clement, G.; Maamache, M.

1985-01-01

The influence of the one-gluon exchange interaction, zero-point energy, and centre-of-mass correction, on the deformation of the nucleon and Δ bags, is studied in the MIT bag model. If the sharp MIT boundary conditions are taken seriously, the strong dependence of the zero-point energy on the deformation leads to the collapse of the N and Δ bags for realistic values of the strong fine structure constant α/sub S/. If on the other hand the zero-point energy is ignored altogether, then the nucleon, spherical for α/sub S/ 3.25, while the Δ is always prolate. The various predictions of the model are, for α/sub S/> or approx. =3.25, consistent with experiment, except for the proton magnetic moment which is only about 40% of the experimental value

MIT LMFBR blanket research project. Final summary report

International Nuclear Information System (INIS)

Driscoll, M.J.

1983-08-01

This is a final summary report on an experimental and analytical program for the investigation of LMFBR blanket characteristics carried out at MIT in the period 1969 to 1983. During this span of time, work was carried out on a wide range of subtasks, ranging from neutronic and photonic measurements in mockups of blankets using the Blanket Test Facility at the MIT Research Reactor, to analytic/numerical investigations of blanket design and economics. The main function of this report is to serve as a resource document which will permit ready reference to the more detailed topical reports and theses issued over the years on the various aspects of project activities. In addition, one aspect of work completed during the final year of the project, on doubly-heterogeneous blanket configurations, is documented for the record

Die Dramatikerin Theresia Walser spricht mit Maria Aparecida Barbosa über das Theaterstück "King Kongs Töchter":Mit einer Einführung von Karina Schuller

OpenAIRE

Barbosa, M.A. (Maria)

2012-01-01

In ihrem Interview spricht die Literaturwissenschaftlerin Maria Aparecida Barbosa mit der Dramatikerin Theresia Walser. Am Beispiel des Theaterstücks King Kongs Töchter (1998), das sich auf groteske Art und Weise mit dem Alltag in einem Altenheim befasst, werden dabei verschiedene Themen angesprochen: Es geht um die Selbstreflexivität des Theaters, um Walsers Verständnis von poetischer Sprache und Realismus sowie um den kreativen Schreibprozess im Allgemeinen. Ergänzt wird das Interview durch...

Kunden- und wettbewerbsorientierte Produktentwicklung mit QFD: Kundenorientierte Produktentwicklung mit Hilfe von Quality Function Deployment (QFD)

OpenAIRE

Schloske, Alexander

2013-01-01

Die Produktentwicklung von heute muss in immer kürzeren Zeiträumen kunden- und kostenorientierte Produkte entwickeln. Zur systematischen Unterstützung dieser Aufgabe im Rahmen der Produktentwicklung wird die Methode Quality Function Deployment (QFD) eingesetzt. Die konsequente Umsetzung der Stimme des Kunden in die Sprache des Unternehmens gelingt mit Quality Function Deployment (QFD). Die Methode wertet systematisch Kundenanforderungen an Produkte aus und führt zu innovativen Lösungen, die s...

Mit1 Transcription Factor Mediates Methanol Signaling and Regulates the Alcohol Oxidase 1 (AOX1) Promoter in Pichia pastoris.

Science.gov (United States)

Wang, Xiaolong; Wang, Qi; Wang, Jinjia; Bai, Peng; Shi, Lei; Shen, Wei; Zhou, Mian; Zhou, Xiangshan; Zhang, Yuanxing; Cai, Menghao

2016-03-18

The alcohol oxidase 1 (AOX1) promoter (P AOX1) of Pichia pastoris is the most powerful and commonly used promoter for driving protein expression. However, mechanisms regulating its transcriptional activity are unclear. Here, we identified a Zn(II)2Cys6-type methanol-induced transcription factor 1 (Mit1) and elucidated its roles in regulating PAOX1 activity in response to glycerol and methanol. Mit1 regulated the expression of many genes involved in methanol utilization pathway, including AOX1, but did not participate in peroxisome proliferation and transportation of peroxisomal proteins during methanol metabolism. Structural analysis of Mit1 by performing domain deletions confirmed its specific and critical role in the strict repression of P AOX1 in glycerol medium. Importantly, Mit1, Mxr1, and Prm1, which positively regulated P AOX1 in response to methanol, were bound to P AOX1 at different sites and did not interact with each other. However, these factors cooperatively activated P AOX1 through a cascade. Mxr1 mainly functioned during carbon derepression, whereas Mit1 and Prm1 functioned during methanol induction, with Prm1 transmitting methanol signal to Mit1 by binding to the MIT1 promoter (P MIT1), thus increasingly expressing Mit1 and subsequently activating P AOX1. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

[R]MIT Research Centre at Delft University of Technology: A Bridge between Research, Education, Society and Profession

Science.gov (United States)

Zijlstra, Hielkje

2009-01-01

In 2006, we launched the [R]MIT Research Centre (Modification, Intervention Transformation) at the Faculty of Architecture at Delft University of Technology. [R]MIT was founded to respond to the need for an integrated, multi-disciplinary approach to the transformation of the built environment. [R]MIT aims to bring momentum to the renewal of…

Thyroid hemiagenesis with immunthyropathy; Schilddruesenhemiagenesie mit Immunthyreopathie

Energy Technology Data Exchange (ETDEWEB)

Mikosch, P.; Gallowitsch, H.J.; Kresnik, E.; Lind, P. [Landeskrankenhaus Klagenfurt (Austria). Abt. fuer Nuklearmedizin und Spezielle Endokrinologie

1999-06-01

A case of Graves` disease occurring in a patient with hemiagenesis is presented. The detection of the rare occurrence of a congential hemiagenesis is often made by either clinical symptoms of thyroid dysfunction or anatomical abnormalities such as nodular goiter. The symptoms of hyperthyroidism in the current case led to the diagnostic confirmation by scintiscanning and ultrasonography of an absent lobe. Anti-thyroid antibody studies documented the presence of Graves` disease within the remaining lobe. (orig.) [Deutsch] Die Hemiagenesie der Schilddruese stellt eine seltene angeborene Veraenderung dar. Diese angeborene Variante der Schilddruesenanlage wird in den meisten Faellen durh Auffaelligkeiten der Funktion oder der Groesse des vorhandenen Schilddruesenlappens zufaellig gefunden. Der Fall einer 57jaehrigen Frau mit einer Schilddruesenhemiagenesie in Kombination mit einer Immunthyreopatie Basedow wird vorgestellt. Die Zuweisung der Patientin zur Untersuchung erfolgte wegen einer Schilddruesenueberfunktion. Die erforderlichen diagnostischen Schritte zur Erstellung dieser beiden Schilddruesenveraenderungen waren ein 99m-Tc-Schilddruesenszintigramm, Ultraschall und Laborparameter der Schilddruese (fT4, TT3, bTSH, TAK, TPO, TRAK). (orig.)

A 16-m Telescope for the Advanced Technology Large Aperture Telescope (ATLAST) Mission

Science.gov (United States)

Lillie, Charles F.; Dailey, D. R.; Polidan, R. S.

2010-01-01

Future space observatories will require increasingly large telescopes to study the earliest stars and galaxies, as well as faint nearby objects. Technologies now under development will enable telescopes much larger than the 6.5-meter diameter James Webb Space Telescope (JWST) to be developed at comparable costs. Current segmented mirror and deployable optics technology enables the 6.5 meter JWST telescope to be folded for launch in the 5-meter diameter Ariane 5 payload fairing, and deployed autonomously after reaching orbit. Late in the next decade, when the Ares V Cargo Launch Vehicle payload fairing becomes operational, even larger telescope can be placed in orbit. In this paper we present our concept for a 16-meter JWST derivative, chord-fold telescope which could be stowed in the 10-m diameter Ares V fairing, plus a description of the new technologies that enable ATLAST to be developed at an affordable price.

Skiing and snowboarding center at Bottrop; Mit Ski oder Snowboard runter von der Halde

Energy Technology Data Exchange (ETDEWEB)

Matthesius, M. [Lenze GmbH und Co KG, Hameln (Germany)

2001-09-01

The 'Alpincenter' at Bottrop is the biggest indoor winter sports center of the world. Its ventilation systems were equipped with specially selected frequency inverters. [German] Skifahren im Hochsommer? Mit dem Snowboard im Ruhrgebiet den Hang hinunter? Beste Wintersportverhaeltnisse an 365 Tagen im Jahr? Und das in Deutschland? Kein Problem. Seit Anfang des Jahres kommen in Bottrop Wintersportfreunde voll auf ihre Kosten. Nach einem halben Jahr Bauzeit hat das Alpincenter seine Pforten geoeffnet. Die Wintersporthalle ist die laengste Anlage auf der Welt. Die gesamte Belueftung wurde mit speziell auf die Klimatechnik (mit Drehzahl geregelten Ventilatoren) abgestimmten Frequenzumrichtern ausgeruestet. (orig./AKF)

Operating performance of the gamma-ray Cherenkov telescope: An end-to-end Schwarzschild–Couder telescope prototype for the Cherenkov Telescope Array

Energy Technology Data Exchange (ETDEWEB)

Dournaux, J.L., E-mail: jean-laurent.dournaux@obspm.fr [GEPI, Observatoire de Paris, PSL Research University, CNRS, Sorbonne Paris Cité, Université Paris Diderot, Place J. Janssen, 92190 Meudon (France); De Franco, A. [Department of Physics, University of Oxford, Keble Road, Oxford OX1 3RH (United Kingdom); Laporte, P. [GEPI, Observatoire de Paris, PSL Research University, CNRS, Sorbonne Paris Cité, Université Paris Diderot, Place J. Janssen, 92190 Meudon (France); White, R. [Max-Planck-Institut für Kernphysik, Saupfercheckweg 1, 69117 Heidelberg (Germany); Greenshaw, T. [University of Liverpool, Oliver Lodge Laboratory, P.O. Box 147, Oxford Street, Liverpool L69 3BX (United Kingdom); Sol, H. [LUTH, Observatoire de Paris, PSL Research University, CNRS, Université Paris Diderot, Place J. Janssen, 92190 Meudon (France); Abchiche, A. [CNRS, Division technique DT-INSU, 1 Place Aristide Briand, 92190 Meudon (France); Allan, D. [Department of Physics and Centre for Advanced Instrumentation, Durham University, South Road, Durham DH1 3LE (United Kingdom); Amans, J.P. [GEPI, Observatoire de Paris, PSL Research University, CNRS, Sorbonne Paris Cité, Université Paris Diderot, Place J. Janssen, 92190 Meudon (France); Armstrong, T.P. [Department of Physics and Centre for Advanced Instrumentation, Durham University, South Road, Durham DH1 3LE (United Kingdom); Balzer, A.; Berge, D. [GRAPPA, University of Amsterdam, Science Park 904, 1098 XH Amsterdam (Netherlands); Boisson, C. [LUTH, Observatoire de Paris, PSL Research University, CNRS, Université Paris Diderot, Place J. Janssen, 92190 Meudon (France); and others

2017-02-11

The Cherenkov Telescope Array (CTA) consortium aims to build the next-generation ground-based very-high-energy gamma-ray observatory. The array will feature different sizes of telescopes allowing it to cover a wide gamma-ray energy band from about 20 GeV to above 100 TeV. The highest energies, above 5 TeV, will be covered by a large number of Small-Sized Telescopes (SSTs) with a field-of-view of around 9°. The Gamma-ray Cherenkov Telescope (GCT), based on Schwarzschild–Couder dual-mirror optics, is one of the three proposed SST designs. The GCT is described in this contribution and the first images of Cherenkov showers obtained using the telescope and its camera are presented. These were obtained in November 2015 in Meudon, France.

Mit1 Transcription Factor Mediates Methanol Signaling and Regulates the Alcohol Oxidase 1 (AOX1) Promoter in Pichia pastoris*

Science.gov (United States)

Wang, Xiaolong; Wang, Qi; Wang, Jinjia; Bai, Peng; Shi, Lei; Shen, Wei; Zhou, Mian; Zhou, Xiangshan; Zhang, Yuanxing; Cai, Menghao

2016-01-01

The alcohol oxidase 1 (AOX1) promoter (PAOX1) of Pichia pastoris is the most powerful and commonly used promoter for driving protein expression. However, mechanisms regulating its transcriptional activity are unclear. Here, we identified a Zn(II)2Cys6-type methanol-induced transcription factor 1 (Mit1) and elucidated its roles in regulating PAOX1 activity in response to glycerol and methanol. Mit1 regulated the expression of many genes involved in methanol utilization pathway, including AOX1, but did not participate in peroxisome proliferation and transportation of peroxisomal proteins during methanol metabolism. Structural analysis of Mit1 by performing domain deletions confirmed its specific and critical role in the strict repression of PAOX1 in glycerol medium. Importantly, Mit1, Mxr1, and Prm1, which positively regulated PAOX1 in response to methanol, were bound to PAOX1 at different sites and did not interact with each other. However, these factors cooperatively activated PAOX1 through a cascade. Mxr1 mainly functioned during carbon derepression, whereas Mit1 and Prm1 functioned during methanol induction, with Prm1 transmitting methanol signal to Mit1 by binding to the MIT1 promoter (PMIT1), thus increasingly expressing Mit1 and subsequently activating PAOX1. PMID:26828066

Rehkitzrettung mit dem Fliegenden Wildretter: Erfahrungen der ersten Feldeinsätze

OpenAIRE

Wimmer, Tilman; Israel, Martin; Haschberger, Peter; Weimann, Anita

2013-01-01

Der Fliegende Wildretter des Deutschen Zentrums für Luft- und Raumfahrt ist als prototypische Kleinserie seit dem Jahr 2010 erfolgreich in Deutsch-land und Österreich im Einsatz, um aus der Luft Wildtiere während der Wiesenmahd aufzuspüren, und diese so vor dem Tod durch das Mähwerk zu retten. Der Prototyp basiert auf einem ferngesteuerten Multikopter, der mit mehreren Kameras ausgestattet ist und damit im Flug zuverlässiger und wesentlich schneller Wildtiere er-kennen kann, als dies mit b...

An innovative telescope control system architecture for SST-GATE telescopes at the CTA Observatory

Science.gov (United States)

Fasola, Gilles; Mignot, Shan; Laporte, Philippe; Abchiche, Abdel; Buchholtz, Gilles; Jégouzo, Isabelle

2014-07-01

SST-GATE (Small Size Telescope - GAmma-ray Telescope Elements) is a 4-metre telescope designed as a prototype for the Small Size Telescopes (SST) of the Cherenkov Telescope Array (CTA), a major facility for the very high energy gamma-ray astronomy of the next three decades. In this 100-telescope array there will be 70 SSTs, involving a design with an industrial view aiming at long-term service, low maintenance effort and reduced costs. More than a prototype, SST-GATE is also a fully functional telescope that shall be usable by scientists and students at the Observatoire de Meudon for 30 years. The Telescope Control System (TCS) is designed to work either as an element of a large array driven by an array controller or in a stand-alone mode with a remote workstation. Hence it is built to be autonomous with versatile interfacing; as an example, pointing and tracking —the main functions of the telescope— are managed onboard, including astronomical transformations, geometrical transformations (e.g. telescope bending model) and drive control. The core hardware is a CompactRIO (cRIO) featuring a real-time operating system and an FPGA. In this paper, we present an overview of the current status of the TCS. We especially focus on three items: the pointing computation implemented in the FPGA of the cRIO —using CORDIC algorithms— since it enables an optimisation of the hardware resources; data flow management based on OPCUA with its specific implementation on the cRIO; and the use of an EtherCAT field-bus for its ability to provide real-time data exchanges with the sensors and actuators distributed throughout the telescope.

Classic Telescopes A Guide to Collecting, Restoring, and Using Telescopes of Yesteryear

CERN Document Server

English, Neil

2013-01-01

Classic Telescopes explores the exciting world of telescopes past, as well as the possibilities involved in acquiring these instruments. What are classic telescopes? First, the book takes a look at the more traditional telescopes built by the great instrument makers of the eighteenth and nineteenth centuries and the dynastic houses founded by the likes of John Dollond, Alvan Clark, Thomas Cooke & Sons and Carl Zeiss, plus some lesser-known luminaries, including John Brashear, John Calver, and Henry Fitz. Instruments constructed from the 1950s until as recently as the early 1990s are now also considered 'classic.' There is thus a very active market for buying and selling these 'modern' classics. The author examines some of the most talked about instruments on the amateur Internet forums, including the Unitron refractors, the Questar 90, a classic 6-inch reflector, the RV-6; a 3-inch F/15 achromat by Fullerscopes; the time-honored AstroScan Richfield reflector; and many, many more. Classic telescopes are of...

H{alpha} ACTIVITY OF OLD M DWARFS: STELLAR CYCLES AND MEAN ACTIVITY LEVELS FOR 93 LOW-MASS STARS IN THE SOLAR NEIGHBORHOOD

Energy Technology Data Exchange (ETDEWEB)

Robertson, Paul; Endl, Michael; Cochran, William D.; Dodson-Robinson, Sarah E., E-mail: paul@astro.as.utexas.edu [Department of Astronomy and McDonald Observatory, University of Texas at Austin, Austin, TX 78712 (United States)

2013-02-10

Through the McDonald Observatory M Dwarf Planet Search, we have acquired nearly 3000 high-resolution spectra of 93 late-type (K5-M5) stars over more than a decade using the High Resolution Spectrograph on the Hobby-Eberly Telescope. This sample provides a unique opportunity to investigate the occurrence of long-term stellar activity cycles for low-mass stars. In this paper, we examine the stellar activity of our targets as reflected in the H{alpha} feature. We have identified periodic signals for six stars, with periods ranging from days to more than 10 years, and find long-term trends for seven others. Stellar cycles with P {>=} 1 year are present for at least 5% of our targets. Additionally, we present an analysis of the time-averaged activity levels of our sample, and search for correlations with other stellar properties. In particular, we find that more massive, earlier type (M0-M2) stars tend to be more active than later type dwarfs. Furthermore, high-metallicity stars tend to be more active at a given stellar mass. We also evaluate H{alpha} variability as a tracer of activity-induced radial velocity (RV) variation. For the M dwarf GJ 1170, H{alpha} variation reveals stellar activity patterns matching those seen in the RVs, mimicking the signal of a giant planet, and we find evidence that the previously identified stellar activity cycle of GJ 581 may be responsible for the recently retracted planet f in that system. In general, though, we find that H{alpha} is not frequently correlated with RV at the precision (typically 6-7 m s{sup -1}) of our measurements.

CROSS-CORRELATIONS AS A COSMOLOGICAL CARBON MONOXIDE DETECTOR

International Nuclear Information System (INIS)

Pullen, Anthony R.; Doré, Olivier; Chang, Tzu-Ching; Lidz, Adam

2013-01-01

We present a new procedure to measure the large-scale carbon monoxide (CO) emissions across cosmic history. As a tracer of large-scale structure (LSS), the CO gas content as a function of redshift can be quantified by its three-dimensional fluctuation power spectra. Furthermore, cross-correlating CO emission with other LSS tracers offers a way to measure the emission as a function of scale and redshift. Here we introduce the model relevant for such a cross-correlation measurement between CO and other LSS tracers, and between different CO rotational lines. We propose a novel use of cosmic microwave background (CMB) data and attempt to extract redshifted CO emissions embedded in the Wilkinson Microwave Anisotropy Probe (WMAP) data set. We cross-correlate the all-sky WMAP7 data with LSS data sets, namely, the photometric quasar sample and the luminous red galaxy sample from the Sloan Digital Sky Survey Data Releases 6 and 7, respectively. We are unable to detect a cross-correlation signal with either CO(1-0) or CO(2-1) lines, mainly due to the instrumental noise in the WMAP data. However, we are able to rule out models more than three times greater than our more optimistic model. We discuss the cross-correlation signal from the thermal Sunyaev-Zeldovich effect and dust as potential contaminants, and quantify their impact for our CO measurements. We discuss forecasts for current CMB experiments and a hypothetical future CO-focused experiment, and propose to cross-correlate CO temperature data with the Hobby-Eberly Telescope Dark Energy Experiment Lyα-emitter sample, for which a signal-to-noise ratio of 58 is possible.

Galaxy redshift surveys with sparse sampling

International Nuclear Information System (INIS)

Chiang, Chi-Ting; Wullstein, Philipp; Komatsu, Eiichiro; Jee, Inh; Jeong, Donghui; Blanc, Guillermo A.; Ciardullo, Robin; Gronwall, Caryl; Hagen, Alex; Schneider, Donald P.; Drory, Niv; Fabricius, Maximilian; Landriau, Martin; Finkelstein, Steven; Jogee, Shardha; Cooper, Erin Mentuch; Tuttle, Sarah; Gebhardt, Karl; Hill, Gary J.

2013-01-01

Survey observations of the three-dimensional locations of galaxies are a powerful approach to measure the distribution of matter in the universe, which can be used to learn about the nature of dark energy, physics of inflation, neutrino masses, etc. A competitive survey, however, requires a large volume (e.g., V survey ∼ 10Gpc 3 ) to be covered, and thus tends to be expensive. A ''sparse sampling'' method offers a more affordable solution to this problem: within a survey footprint covering a given survey volume, V survey , we observe only a fraction of the volume. The distribution of observed regions should be chosen such that their separation is smaller than the length scale corresponding to the wavenumber of interest. Then one can recover the power spectrum of galaxies with precision expected for a survey covering a volume of V survey (rather than the volume of the sum of observed regions) with the number density of galaxies given by the total number of observed galaxies divided by V survey (rather than the number density of galaxies within an observed region). We find that regularly-spaced sampling yields an unbiased power spectrum with no window function effect, and deviations from regularly-spaced sampling, which are unavoidable in realistic surveys, introduce calculable window function effects and increase the uncertainties of the recovered power spectrum. On the other hand, we show that the two-point correlation function (pair counting) is not affected by sparse sampling. While we discuss the sparse sampling method within the context of the forthcoming Hobby-Eberly Telescope Dark Energy Experiment, the method is general and can be applied to other galaxy surveys

The Lithium-, r- and s-Enhanced Metal-Poor Giant HK-II 17435-00532

International Nuclear Information System (INIS)

Roederer, Ian U.; Prieto, Carlos Allende; Sneden, Christopher; Frebel, Anna; Shetrone, Matthew; Rhee, Jaehyon; Gallino, Roberto; Bisterzo, Sara; Beers, Timothy C.; Cowan, John J.

2008-01-01

We present the first detailed abundance analysis of the metal-poor giant HK-II 17435-00532. This star was observed as part of the University of Texas Long-Term Chemical Abundances of Stars in the Halo (CASH) Project. A spectrum was obtained with the High Resolution Spectrograph (HRS) on the Hobby-Eberly Telescope with a resolving power of R∼15000. Our analysis reveals that this star may be located on the red giant branch, red horizontal branch, or early asymptotic giant branch. We find that this metal-poor ([Fe/H] = -2.2) star has an unusually high lithium abundance (logε(Li) = +2.1), mild carbon ([C/Fe] = +0.7) and sodium ([Na/Fe] = +0.6) enhancement, as well as enhancement of both s-process ([Ba/Fe] = +0.8) and r-process ([Eu/Fe] = +0.5) material. The high Li abundance can be explained by self-enrichment through extra mixing mechanisms that connect the convective envelope with the outer regions of the H-burning shell. If so, HK-II 17435-00532 is the most metal-poor starin which this short-lived phase of Li enrichment has been observed. The r- and s-process material was not produced in this star but was either present in the gas from which HK-II 17435-00532 formed or was transferred to it from a more massive binary companion. Despite the current non-detection of radial velocity variations (over a time span of ∼180 days), it is possible that HK-II 17435-00532 is in a long-period binary system, similar to other stars with both r and s enrichment

COMMENT ON THE BLACK HOLE RECOIL CANDIDATE QUASAR SDSS J092712.65+294344.0

International Nuclear Information System (INIS)

Shields, G. A.; Bonning, E. W.; Salviander, S.

2009-01-01

The Sloan Digital Sky Survey (SDSS) quasar J092712.65+294344.0 has been proposed as a candidate for a supermassive black hole (∼10 8.8 M sun ) ejected at high speed from the host galactic nucleus by gravitational radiation recoil, or alternatively for a supermassive black hole binary. This is based on a blueshift of 2650 km s -1 of the broad emission lines ('b-system') relative to the narrow emission lines ('r-system') presumed to reflect the galaxy velocity. New observations with the Hobby-Eberly Telescope (HET) confirm the essential features of the spectrum. We note a third redshift system, characterized by weak, narrow emission lines of [O III] and [O II] at an intermediate velocity 900 km s -1 redward of the broad-line velocity ('i-system'). A composite spectrum of SDSS QSOs similar to J0927+2943 illustrates the feasibility of detecting the calcium K absorption line in spectra of sufficient quality. The i-system may represent the QSO host galaxy or a companion. Photoionization requires the black hole to be ∼3 kpc from the r-system emitting gas, implying that we are observing the system only 10 6 yr after the recoil event and contributing to the low probability of observing such a system. The HET observations give an upper limit of 10 km s -1 per year on the rate of change of the velocity difference between the r- and b-systems, constraining the orbital phase in the binary model. These considerations and the presence of a cluster of galaxies apparently containing J0927+2943 favor the idea that this system represents a superposition of two active galactic nuclei.

Hα ACTIVITY OF OLD M DWARFS: STELLAR CYCLES AND MEAN ACTIVITY LEVELS FOR 93 LOW-MASS STARS IN THE SOLAR NEIGHBORHOOD

International Nuclear Information System (INIS)

Robertson, Paul; Endl, Michael; Cochran, William D.; Dodson-Robinson, Sarah E.

2013-01-01

Through the McDonald Observatory M Dwarf Planet Search, we have acquired nearly 3000 high-resolution spectra of 93 late-type (K5-M5) stars over more than a decade using the High Resolution Spectrograph on the Hobby-Eberly Telescope. This sample provides a unique opportunity to investigate the occurrence of long-term stellar activity cycles for low-mass stars. In this paper, we examine the stellar activity of our targets as reflected in the Hα feature. We have identified periodic signals for six stars, with periods ranging from days to more than 10 years, and find long-term trends for seven others. Stellar cycles with P ≥ 1 year are present for at least 5% of our targets. Additionally, we present an analysis of the time-averaged activity levels of our sample, and search for correlations with other stellar properties. In particular, we find that more massive, earlier type (M0-M2) stars tend to be more active than later type dwarfs. Furthermore, high-metallicity stars tend to be more active at a given stellar mass. We also evaluate Hα variability as a tracer of activity-induced radial velocity (RV) variation. For the M dwarf GJ 1170, Hα variation reveals stellar activity patterns matching those seen in the RVs, mimicking the signal of a giant planet, and we find evidence that the previously identified stellar activity cycle of GJ 581 may be responsible for the recently retracted planet f in that system. In general, though, we find that Hα is not frequently correlated with RV at the precision (typically 6-7 m s –1 ) of our measurements.

THE PTF ORION PROJECT: A POSSIBLE PLANET TRANSITING A T-TAURI STAR

International Nuclear Information System (INIS)

Van Eyken, Julian C.; Ciardi, David R.; Von Braun, Kaspar; Kane, Stephen R.; Plavchan, Peter; Akeson, Rachel L.; Beichman, Charles A.; Gelino, Dawn M.; Bender, Chad F.; Mahadevan, Suvrath; Brown, Timothy M.; Fulton, Benjamin J.; Shporer, Avi; Crepp, Justin R.; Howard, Andrew W.; Marcy, Geoffrey W.; Howell, Steve B.; Szkody, Paula; Boden, Andrew F.; Hoard, D. W.

2012-01-01

We report observations of a possible young transiting planet orbiting a previously known weak-lined T-Tauri star in the 7-10 Myr old Orion-OB1a/25-Ori region. The candidate was found as part of the Palomar Transient Factory (PTF) Orion project. It has a photometric transit period of 0.448413 ± 0.000040 days, and appears in both 2009 and 2010 PTF data. Follow-up low-precision radial velocity (RV) observations and adaptive optics imaging suggest that the star is not an eclipsing binary, and that it is unlikely that a background source is blended with the target and mimicking the observed transit. RV observations with the Hobby-Eberly and Keck telescopes yield an RV that has the same period as the photometric event, but is offset in phase from the transit center by ≈ – 0.22 periods. The amplitude (half range) of the RV variations is 2.4 km s –1 and is comparable with the expected RV amplitude that stellar spots could induce. The RV curve is likely dominated by stellar spot modulation and provides an upper limit to the projected companion mass of M p sin i orb ∼ Jup ; when combined with the orbital inclination, i orb , of the candidate planet from modeling of the transit light curve, we find an upper limit on the mass of the planetary candidate of M p ∼ Jup . This limit implies that the planet is orbiting close to, if not inside, its Roche limiting orbital radius, so that it may be undergoing active mass loss and evaporation.

Spin-Orbit Misalignments of Three Jovian Planets via Doppler Tomography

Science.gov (United States)

Johnson, Marshall C.; Cochran, William D.; Addison, Brett C.; Tinney, Chris G.; Wright, Duncan J.

2017-10-01

We present measurements of the spin-orbit misalignments of the hot Jupiters HAT-P-41 b and WASP-79 b, and the aligned warm Jupiter Kepler-448 b. We obtain these measurements with Doppler tomography, where we spectroscopically resolve the line profile perturbation during the transit due to the Rossiter-McLaughlin effect. We analyze time series spectra obtained during portions of five transits of HAT-P-41 b, and find a value of the spin-orbit misalignment of λ =-{22.1}-6.0{+0.8^\\circ }. We reanalyze the radial velocity Rossiter-McLaughlin data on WASP-79 b obtained by Addison et al. using Doppler tomographic methodology. We measure λ =-{99.1}-3.9{+4.1^\\circ }, consistent with but more precise than the value found by Addison et al. For Kepler-448 b we perform a joint fit to the Kepler light curve, Doppler tomographic data, and a radial velocity data set from Lillo-Box et al. We find an approximately aligned orbit (λ =-{7.1}-2.8{+4.2^\\circ }), in agreement with the value found by Bourrier et al. Through analysis of the Kepler light curve we measure a stellar rotation period of {P}{rot}=1.27+/- 0.11 days, and use this to argue that the full three-dimensional spin-orbit misalignment is small, \\psi ˜ 0^\\circ . Based in part on observations obtained with the Hobby-Eberly Telescope, which is a joint project of the University of Texas at Austin, the Pennsylvania State University, Stanford University, Ludwig-Maximilians-Universität München, and Georg-August-Universität Göttingen.

Nuclear matter as an MIT bag crystal

International Nuclear Information System (INIS)

Zhang, Q.; Derreth, C.; Schaefer, A.; Greiner, W.

1986-01-01

An MIT bag crystal model of nuclear matter is formulated. The energy bands of the quarks are calculated as a function of the overlap between adjacent bags. A clear indication of substantial overlap is found. Accordingly, infinite nuclear matter is more similar to a quark gas than to a nucleonic structure. (author)

Alignment and phasing of deployable telescopes

Science.gov (United States)

Woolf, N. J.; Ulich, B. L.

1983-01-01

The experiences in coaligning and phasing the Multi-Mirror Telescope (MMT), together with studies in setting up radio telescopes, are presented. These experiences are discussed, and on the basis they furnish, schemes are suggested for coaligning and phasing four large future telescopes with complex primary mirror systems. These telescopes are MT2, a 15-m-equivalent MMT, the University of California Ten Meter Telescope, the 10 m sub-mm wave telescope of the University of Arizona and the Max Planck Institute for Radioastronomy, and the Large Deployable Reflector, a future space telescope for far-IR and sub-mm waves.

OVERVIEW OF THE ATACAMA COSMOLOGY TELESCOPE: RECEIVER, INSTRUMENTATION, AND TELESCOPE SYSTEMS

International Nuclear Information System (INIS)

Swetz, D. S.; Devlin, M. J.; Dicker, S. R.; Ade, P. A. R.; Amiri, M.; Battistelli, E. S.; Burger, B.; Halpern, M.; Hasselfield, M.; Appel, J. W.; Essinger-Hileman, T.; Fisher, R. P.; Fowler, J. W.; Hincks, A. D.; Jarosik, N.; Chervenak, J.; Doriese, W. B.; Hilton, G. C.; Irwin, K. D.; Duenner, R.

2011-01-01

The Atacama Cosmology Telescope was designed to measure small-scale anisotropies in the cosmic microwave background and detect galaxy clusters through the Sunyaev-Zel'dovich effect. The instrument is located on Cerro Toco in the Atacama Desert, at an altitude of 5190 m. A 6 m off-axis Gregorian telescope feeds a new type of cryogenic receiver, the Millimeter Bolometer Array Camera. The receiver features three 1000-element arrays of transition-edge sensor bolometers for observations at 148 GHz, 218 GHz, and 277 GHz. Each detector array is fed by free space millimeter-wave optics. Each frequency band has a field of view of approximately 22' x 26'. The telescope was commissioned in 2007 and has completed its third year of operations. We discuss the major components of the telescope, camera, and related systems, and summarize the instrument performance.

Overview of the Atacama Cosmology Telescope: Receiver, Instrumentation, and Telescope Systems

Science.gov (United States)

Swetz, D. S.; Ade, P. A. R.; Amiri, M.; Appel, J. W.; Battistelli, E. S.; Burger, B.; Chervenak, J.; Devlin, M. J.; Dicker, S. R.; Doriese, W. B.; Dünner, R.; Essinger-Hileman, T.; Fisher, R. P.; Fowler, J. W.; Halpern, M.; Hasselfield, M.; Hilton, G. C.; Hincks, A. D.; Irwin, K. D.; Jarosik, N.; Kaul, M.; Klein, J.; Lau, J. M.; Limon, M.; Marriage, T. A.; Marsden, D.; Martocci, K.; Mauskopf, P.; Moseley, H.; Netterfield, C. B.; Niemack, M. D.; Nolta, M. R.; Page, L. A.; Parker, L.; Staggs, S. T.; Stryzak, O.; Switzer, E. R.; Thornton, R.; Tucker, C.; Wollack, E.; Zhao, Y.

2011-06-01

The Atacama Cosmology Telescope was designed to measure small-scale anisotropies in the cosmic microwave background and detect galaxy clusters through the Sunyaev-Zel'dovich effect. The instrument is located on Cerro Toco in the Atacama Desert, at an altitude of 5190 m. A 6 m off-axis Gregorian telescope feeds a new type of cryogenic receiver, the Millimeter Bolometer Array Camera. The receiver features three 1000-element arrays of transition-edge sensor bolometers for observations at 148 GHz, 218 GHz, and 277 GHz. Each detector array is fed by free space millimeter-wave optics. Each frequency band has a field of view of approximately 22' × 26'. The telescope was commissioned in 2007 and has completed its third year of operations. We discuss the major components of the telescope, camera, and related systems, and summarize the instrument performance.

Underground storage with floating cover. An overview; Erdbeckenspeicher mit schwimmender Abdeckung. Eine Uebersicht

Energy Technology Data Exchange (ETDEWEB)

Heller, A.; Maureschat, G.; Duer, K. [Technical Univ. of Denmark, Lyngby (Denmark). Dept. of Buildings and Energy

1998-12-31

A number of underground stores have been developed in recent years in Denmark. The development has been subsidised with funds of `Development program renewable energy` launched by the Danish Ministry for Environment and Energy. First experience reports on underground storage show that more emphasis must be put on the development of storage sealing and cover construction. Hence research works currently focuses on the investigation of liner material and further development of floating cover constructions. The target is the development of underground storage using solar energy for heating that can compete with conventional heating systems technically and economically. (orig.) [Deutsch] In Daenemark hat man in den letzten Jahren eine Reihe von Erdbeckenspeichern entwickelt. Die Entwicklung wird mit Mitteln aus dem `Entwicklungsprogramm Erneuerbare Energie` vom daenischen Umwelt- und Energieministerium finanziell gefoerdert. Die ersten Erfahrungen mit Erdbeckenspeichern haben gezeigt, dass ein verstaerkter Einsatz bei der Entwicklung von Abdichtungen des Speichers und von Deckelkonstruktionen gefordert ist. Deshalb wird in Daenemark aktuell mit der Untersuchung von Linermaterialien und der Weiterentwicklung von schwimmenden Deckelkonstruktionen gearbeitet. Das Ziel dieser Arbeit ist es, Erdbeckenspeicher zu entwickeln, die die Ausnutzung von Sonnenenergie zur Waermeversorgung im Vergleich mit herkoemmlicher Waermeversorgung sowohl technisch als auch oekonomisch konkurrenzfaehig macht. (orig.)

MRI for therapy planning in patients with atrial septum defects; MRT zur Therapieplanung bei Patienten mit Vorhofseptumdefekt

Energy Technology Data Exchange (ETDEWEB)

Huber, A.; Rummeny, E. [Klinikum rechts der Isar, Technische Universitaet Muenchen, Institut fuer Radiologie, Muenchen (Germany); Prompona, M.; Reiser, M.; Theisen, D. [Klinikum der Ludwig-Maximilians-Universitaet Muenchen, Campus Grosshadern, Institut fuer Klinische Radiologie, Muenchen (Germany); Kozlik-Feldmann, R. [Klinikum der Ludwig-Maximilians-Universitaet Muenchen, Campus Grosshadern, Klinik und Poliklinik fuer Kinderkardiologie, Muenchen (Germany); Muehling, O. [Klinikum der Ludwig-Maximilians-Universitaet Muenchen, Campus Grosshadern, Medizinische Klinik I, Muenchen (Germany)

2011-01-15

The aim of this study was to determine the value of a combined magnetic resonance imaging (MRI) protocol including steady-state free precession (SSFP) imaging, phase-contrast measurements and contrast-enhanced MR angiography (CE-MRA) for presurgical or preinterventional diagnostic imaging in patients with suspected atrial septum defects. Out of 65 MRI studies of patients with suspected atrial septum defects, 56 patients were included in the study. The atrial septum defects were identified on cine images. Velocity encoded flow measurements were used to determine shunt volumes, which were compared with invasive oxymetry in 24 patients. Contrast-enhanced MRI was used to assess the thoracic vessels in order to detect vascular anomalies. The findings were compared with the intraoperative results. A total of 24 patients with high shunt volumes were treated either surgically (16 patients) or interventionally (8 patients) and 32 patients with low shunt volumes did not require surgical or interventional treatment. The vascular anomaly, which in all cases was anomalous pulmonary venous return, was confirmed by the intraoperative findings. The type and location of atrial septal defects which required treatment, were confirmed intraoperatively or during the intervention. The results of shunt quantification by MRI showed a good correlation with the results of invasive oximetry (r=0.91, p <0.0001). A combined MRI protocol including cine SSFP images, velocity-encoded flow measurements and CE-MRA is an accurate method for preoperative and preinterventional evaluation of atrial septum defects. (orig.) [German] Ziel war es, die Wertigkeit eines kombinierten MRT-Protokolls aus Funktionsuntersuchung, Flussmessung und MR-Angiographie zur praeoperativen oder -interventionellen Abklaerung bei Patienten mit Vorhofseptumdefekt zu evaluieren. Ingesamt wurden 56 Patienten mit Vorhofseptumdefekt aus einem Kollektiv von 65 Patienten mit Verdacht auf Vorhofseptumdefekt, die im MRT untersucht

Therapie einer postoperativ entstandenen zystischen Raumforderung mit Picibanil (OK-432): Ein Fallbericht

OpenAIRE

Schlüter, A; Weller, P; Mattheis, S; Lang, S

2014-01-01

Einleitung: Picibanil (=OK432) ist ein Lysat bestehend aus Penicillin G und mit H2O2 attenuiertem Streptococcus pyogenes. In den letzten Jahrzehnten wurde Picibanil zur Therapie von Pleuraergüssen, Lymphangiomen, Chylusfisteln, medianen Halszysten und Ranulae eingesetzt. Es verursacht eine Immunreaktion mit aseptischer Entzündung. Dies führt zu einer Zerstörung des Endothels und konsekutiv zu einer Verklebung und Schrumpfung des Zystensacks.Falldarstellung: Wir berichten über einen 40-jähri...

Alt-Az Spacewatch Telescope

Science.gov (United States)

Gehrels, Tom

1997-01-01

This grant funded about one third of the cost of the construction of a telescope with an aperture 1.8 meters in diameter to discover asteroids and comets and investigate the statistics of their populations and orbital distributions. This telescope has been built to the PI's specifications and installed in a dome on Kitt Peak mountain in Arizona. Funds for the dome and building were provided entirely by private sources. The dome building and telescope were dedicated in a ceremony at the site on June 7, 1997. The attached abstract describes the parameters of the telescope. The telescope is a new item of capital property. It is permanently located in University of Arizona building number 910 in the Steward Observatory compound on Kitt Peak mountain in the Tohono O'odham Nation, Arizona. fts property tag number is A252107. This grant did not include funds for the coma corrector lens, instrument derotator, CCD detector, detector electronics, or computers to acquire or process the data. It also did not include funds to operate the telescope or conduct research with it. Funds for these items and efforts are pending from NASA and other sources.

Endokrinologische Behandlung der Geschlechtsdysphorie bei Menschen mit Geschlechtsinkongruenz

Directory of Open Access Journals (Sweden)

Flütsch N

2015-01-01

Full Text Available Es gibt Menschen, die die innere Gewissheit besitzen, dass ihre Geschlechtsidentität nicht zu ihrem biologischen Ursprungsgeschlecht passt. Durch die Entwicklungen in der Medizin in den letzten hundert Jahren ist es möglich geworden, die körperlichen Geschlechtsmerkmale an das innerlich erlebte Geschlecht anzupassen. Die Zahl der Hilfesuchenden in den ärztlichen Ambulanzen und Privatpraxen hat in den vergangenen Jahren deutlich zugenommen. Das Vorgehen bei der Diagnostik und Therapieeinleitung erlebt zurzeit eine deutliche Veränderung hin zu mehr Patientenzentriertheit und Individualisierung des Transitionsprozesses. Dabei bildet die geschlechtsangleichende Hormontherapie ein wesentliches Standbein in der körperlichen Angleichung an das Gegengeschlecht. Unter Beachtung von bestimmten Sicherheitsaspekten ist eine Hormontherapie mit Sexualhormonen sicher und einfach durchzuführen. Regelmäßige Verlaufskontrollen sowie der offene und affirmative Umgang mit den Betroffenen tragen zudem wesentlich zur Sicherheit in der Behandlung bei.

The R Package MitISEM: Efficient and Robust Simulation Procedures for Bayesian Inference

Directory of Open Access Journals (Sweden)

Nalan Baştürk

2017-07-01

Full Text Available This paper presents the R package MitISEM (mixture of t by importance sampling weighted expectation maximization which provides an automatic and flexible two-stage method to approximate a non-elliptical target density kernel - typically a posterior density kernel - using an adaptive mixture of Student t densities as approximating density. In the first stage a mixture of Student t densities is fitted to the target using an expectation maximization algorithm where each step of the optimization procedure is weighted using importance sampling. In the second stage this mixture density is a candidate density for efficient and robust application of importance sampling or the Metropolis-Hastings (MH method to estimate properties of the target distribution. The package enables Bayesian inference and prediction on model parameters and probabilities, in particular, for models where densities have multi-modal or other non-elliptical shapes like curved ridges. These shapes occur in research topics in several scientific fields. For instance, analysis of DNA data in bio-informatics, obtaining loans in the banking sector by heterogeneous groups in financial economics and analysis of education's effect on earned income in labor economics. The package MitISEM provides also an extended algorithm, 'sequential MitISEM', which substantially decreases computation time when the target density has to be approximated for increasing data samples. This occurs when the posterior or predictive density is updated with new observations and/or when one computes model probabilities using predictive likelihoods. We illustrate the MitISEM algorithm using three canonical statistical and econometric models that are characterized by several types of non-elliptical posterior shapes and that describe well-known data patterns in econometrics and finance. We show that MH using the candidate density obtained by MitISEM outperforms, in terms of numerical efficiency, MH using a simpler

The MIT miniaturized disk bend test

International Nuclear Information System (INIS)

Harling, O.K.; Lee, M.; Sohn, D.S.; Kohse, G.; Lau, C.W.

1983-01-01

A miniaturized disk bend test (MDBT) using transmission electron microscopy specimens for the determination of various mechanical properties is being developed at MIT. Recent progress in obtaining strengths and ductilities of highly irradiated metal alloys is reviewed. Possibilities exist for applying the MDBT approach to the determination of other mechanical properties. Progress in fatigue testing and in determination of the ductile-to-brittle transition temperature is reviewed briefly

The great Melbourne telescope

CERN Document Server

Gillespie, Richard

2011-01-01

Erected at Melbourne Observatory in 1869, the telescope was the second largest in the world, designed to explore the nature of the nebulae in the southern skies. Richard Gillespie, head of the History and Technology department at the Melbourne museum has written an entertaining account of the telescope's extraordinary history and tells the story through an amazing cast of characters whose lives intersected with the telescope.

Automatizace MitM útoku pro dešifrování SSL/TLS

OpenAIRE

Marušic, Marek

2016-01-01

Protokoly SSL/TLS sú používané pre šifráciu sieťovéhej prevádzky. Poskytujú bezpečnú komunikáciu medzi klientmi a servermi. Komunikácia môže byť odpočúvaná pomocou MitM útoku. Táto práca je zameraná na atuomatizovanie MitM útoku a demonštráciu jej výsledkov. Automatizáciou sa zjednoduší spustenie útoku bez nutnosti študovania rôznych manuálových stránok a aby sa používatelia vyhli pracnej konfigurácii MitM zariadenia a mohli jednoducho zachytiť a analyzovať SSL/TLS komunikáciu. Automatizácia ...

Biogas - a new energy source saves fossil resources; Biogas - mit neuer Energie Ressourcen schonen

Energy Technology Data Exchange (ETDEWEB)

Thoss, C. (comp.)

2001-07-01

The new German Renewable Energy Sources Act (EEG) of 2000 made conditions for biogas more favourable - small wonder, as the German Biogas Association (Fachverband Biogas e.V.) co-operated with written expert opinions and many discussions with decision-makers. The subjects discussed at the 10th Biogas Conference reflect the current situation and will provide a basis for committee work in 2001. [German] Im Jahr 2000 haben sich die gesetzlichen Rahmenbedingungen fuer den Biogasbereich mit dem Inkrafttreten des erneuerbaren Energiegesetz (EEG) sehr positiv entwickelt. Der Fachverband Biogas e.V. hat mit schriftlichen Stellungnahmen und in vielen Gespraechen mit Entscheidungstraegern diese Bedingungen mitgestaltet. In Zukunft gibt es noch viele Aufgaben fuer eine effektive Interessenvertretung der Biogasbranche auf Laender- und Bundesebene. Die Themen, die auf der 10. Biogastagung diskutiert werden, spiegeln die Fragen wieder, die unter Experten derzeit intensiv diskutiert werden. Die Ergebnisse des Erfahrungsaustausches auf dieser Tagung werden die Grundlage fuer die Arbeit der Gremien im Fachverband Biogas im Jahr 2001 sein. Mit dem vorliegenden Tagungsband ist es gelungen, die Basis fuer die fachlichen Gespraeche waehrend und nach der Tagung schaffen. (orig.)

Scientific Performance Analysis of the SYZ Telescope Design versus the RC Telescope Design

Science.gov (United States)

Ma, Donglin; Cai, Zheng

2018-02-01

Recently, Su et al. propose an innovative design, referred as the “SYZ” design, for China’s new project of a 12 m optical-infrared telescope. The SYZ telescope design consists of three aspheric mirrors with non-zero power, including a relay mirror below the primary mirror. SYZ design yields a good imaging quality and has a relatively flat field curvature at Nasmyth focus. To evaluate the science-compatibility of this three-mirror telescope, in this paper, we thoroughly compare the performance of SYZ design with that of Ritchey–Chrétien (RC) design, a conventional two-mirror telescope design. Further, we propose the Observing Information Throughput (OIT) as a metric for quantitatively evaluating the telescopes’ science performance. We find that although a SYZ telescope yields a superb imaging quality over a large field of view, a two-mirror (RC) telescope design holds a higher overall throughput, a better diffraction-limited imaging quality in the central field of view (FOV < 5‧) which is better for the performance of extreme Adaptive Optics (AO), and a generally better scientific performance with a higher OIT value. D. Ma & Z. Cai contributed equally to this paper.

[Bernt Ahrenholz : Verweise mit Demonstrativa im Gesprochenen Deutsch...] / Klaus Geyer

Index Scriptorium Estoniae

Geyer, Klaus

2008-01-01

Arvustus: Ahrenholz, Bernt. Verweise mit Demonstrativa im gesprochenen Deutsch : Grammatik, Zweitspracherwerb und Deutsch als Fremdsprache. Berlin ; New York : de Gruyter, 2007. (Linguistik - Impulse & Tendenzen ; 17)

A New Instrument for the IRTF: the MIT Optical Rapid Imaging System (MORIS)

Science.gov (United States)

Gulbis, Amanda A. S.; Elliot, J. L.; Rojas, F. E.; Bus, S. J.; Rayner, J. T.; Stahlberger, W. E.; Tokunaga, A. T.; Adams, E. R.; Person, M. J.

2010-10-01

NASA's 3-m Infrared Telescope Facility (IRTF) on Mauna Kea, HI plays a leading role in obtaining planetary science observations. However, there has been no capability for high-speed, visible imaging from this telescope. Here we present a new IRTF instrument, MORIS, the MIT Optical Rapid Imaging System. MORIS is based on POETS (Portable Occultation Eclipse and Transit Systems; Souza et al., 2006, PASP, 118, 1550). Its primary component is an Andor iXon camera, a 512x512 array of 16-micron pixels with high quantum efficiency, low read noise, low dark current, and full-frame readout rates of between 3.5 Hz (6 e /pixel read noise) and 35 Hz (49 e /pixel read noise at electron-multiplying gain=1). User-selectable binning and subframing can increase the cadence to a few hundred Hz. An electron-multiplying mode can be employed for photon counting, effectively reducing the read noise to sub-electron levels at the expense of dynamic range. Data cubes, or individual frames, can be triggered to nanosecond accuracy using a GPS. MORIS is mounted on the side-facing widow of SpeX (Rayner et al. 2003, PASP, 115, 362), allowing simultaneous near-infrared and visible observations. The mounting box contains 3:1 reducing optics to produce a 60 arcsec x 60 arcsec field of view at f/12.7. It hosts a ten-slot filter wheel, with Sloan g×, r×, i×, and z×, VR, Johnson V, and long-pass red filters. We describe the instrument design, components, and measured characteristics. We report results from the first science observations, a 24 June 2008 stellar occultation by Pluto. We also discuss a recent overhaul of the optical path, performed in order to eliminate scattered light. This work is supported in part by NASA Planetary Major Equipment grant NNX07AK95G. We are indebted to the University of Hawai'i Institute for Astronomy machine shop, in particular Randy Chung, for fabricating instrument components.

The knockdown of OsVIT2 and MIT affects iron localization in rice seed.

Science.gov (United States)

Bashir, Khurram; Takahashi, Ryuichi; Akhtar, Shamim; Ishimaru, Yasuhiro; Nakanishi, Hiromi; Nishizawa, Naoko K

2013-11-20

The mechanism of iron (Fe) uptake in plants has been extensively characterized, but little is known about how Fe transport to different subcellular compartments affects Fe localization in rice seed. Here, we discuss the characterization of a rice vacuolar Fe transporter 2 (OsVIT2) T-DNA insertion line (osvit2) and report that the knockdown of OsVIT2 and mitochondrial Fe transporter (MIT) expression affects seed Fe localization. osvit2 plants accumulated less Fe in their shoots when grown under normal or excess Fe conditions, while the accumulation of Fe was comparable to that in wild-type (WT) plants under Fe-deficient conditions. The accumulation of zinc, copper, and manganese also changed significantly in the shoots of osvit2 plants. The growth of osvit2 plants was also slow compared to that of WT plants. The concentration of Fe increased in osvit2 polished seeds. Previously, we reported that the expression of OsVIT2 was higher in MIT knockdown (mit-2) plants, and in this study, the accumulation of Fe in mit-2 seeds decreased significantly. These results suggest that vacuolar Fe trafficking is important for plant Fe homeostasis and distribution, especially in plants grown in the presence of excess Fe. Moreover, changes in the expression of OsVIT2 and MIT affect the concentration and localization of metals in brown rice as well as in polished rice seeds.

MitProNet: A knowledgebase and analysis platform of proteome, interactome and diseases for mammalian mitochondria.

Directory of Open Access Journals (Sweden)

Jiabin Wang

Full Text Available Mitochondrion plays a central role in diverse biological processes in most eukaryotes, and its dysfunctions are critically involved in a large number of diseases and the aging process. A systematic identification of mitochondrial proteomes and characterization of functional linkages among mitochondrial proteins are fundamental in understanding the mechanisms underlying biological functions and human diseases associated with mitochondria. Here we present a database MitProNet which provides a comprehensive knowledgebase for mitochondrial proteome, interactome and human diseases. First an inventory of mammalian mitochondrial proteins was compiled by widely collecting proteomic datasets, and the proteins were classified by machine learning to achieve a high-confidence list of mitochondrial proteins. The current version of MitProNet covers 1124 high-confidence proteins, and the remainders were further classified as middle- or low-confidence. An organelle-specific network of functional linkages among mitochondrial proteins was then generated by integrating genomic features encoded by a wide range of datasets including genomic context, gene expression profiles, protein-protein interactions, functional similarity and metabolic pathways. The functional-linkage network should be a valuable resource for the study of biological functions of mitochondrial proteins and human mitochondrial diseases. Furthermore, we utilized the network to predict candidate genes for mitochondrial diseases using prioritization algorithms. All proteins, functional linkages and disease candidate genes in MitProNet were annotated according to the information collected from their original sources including GO, GEO, OMIM, KEGG, MIPS, HPRD and so on. MitProNet features a user-friendly graphic visualization interface to present functional analysis of linkage networks. As an up-to-date database and analysis platform, MitProNet should be particularly helpful in comprehensive studies of

A METABOLIC SIGNATURE FOR LONG-LIFE IN THE C. ELEGANS MIT MUTANTS

Science.gov (United States)

Butler, Jeffrey A.; Mishur, Robert J.; Bhaskaran, Shylesh; Rea, Shane L.

2012-01-01

SUMMARY Mit mutations that disrupt function of the mitochondrial electron transport chain can, inexplicably, prolong Caenorhabditis elegans lifespan. In this study we use a metabolomics approach to identify an ensemble of mitochondrial-derived α-ketoacids and α-hydroxyacids that are produced by long-lived Mit mutants but not by other long-lived mutants or by short-lived mitochondrial mutants. We show that accumulation of these compounds is dependent upon concerted inhibition of three α-ketoacid dehydrogenases that share dihydrolipoamide dehydrogenase (DLD) as a common subunit, a protein previously linked in humans with increased risk of Alzheimer’s disease. When the expression of DLD in wild type animals was reduced using RNA interference we observed an unprecedented effect on lifespan - as RNAi dosage was increased lifespan was significantly shortened but, at higher doses, it was significantly lengthened, suggesting DLD plays a unique role in modulating length of life. Our findings provide novel insight into the origin of the Mit phenotype. PMID:23173729

Dewatering of sludge using the hydrosoft high-pressure process; Entwaessern von Schlaemmen mit dem Hydrosoft-Hochdruckverfahren

Energy Technology Data Exchange (ETDEWEB)

Eder, C.; Eder, G. [Christian Eder Technology GbR, Neunkirchen (Germany)

1999-07-01

The hydrosoft process permits to dewater sludge, especially also sludge from municipal sewage treatment plant, until it contains a high proportion of dry substance. For existing dewatering systems equipped with the long-lived chamber filter presses, too, the dry matter content of the filter cake can be substantially increased using the hydrosoft process; only the pump system must be retrofitted. As a preliminary measure, tests with mobile pilot plants should be carried out. (orig.) [German] Mit dem Hydrosoft-Verfahren besteht die Moeglichkeit Schlaemme, insbesondere auch Schlaemme aus kommunalen Klaeranlagen, auf hohe Trockensubstanz-Gehalte zu entwaessern. Auch bei bestehenden Entwaesserungsanlagen, die mit den langlebigen Kammerfilterpressen ausgeruestet sind, koennen die Trockensubstanzgehalte der Filterkuchen mit dem Hydrosoft-Verfahren, fuer das dann nur noch das Pumpsystem nachgeruestet werden muss, wesentlich angehoben werden. Vorausgehen sollten jeweils Vorversuche mit mobilen Versuchsanlagen. (orig.)

Virtual Telescope Alignment System

Data.gov (United States)

National Aeronautics and Space Administration — Next-generation space telescopes require two spacecraft to fly in a coordinated fashion in space forming a virtual telescope. Achieving and maintaining this precise...

"Drugwatch": Forschung mit Schlüsselprofessionellen und illegalen Drogenusern zur Identifikation von Drogentrends

OpenAIRE

Mason, Mark; Baker, Oswin; Hardy, Rebecca

2007-01-01

Die revidierte "United Kingdom Anti-Drugs Strategy" hat Lücken im Wissen über Drogen verdeutlicht: Insbesondere die Dynamiken, die mit der Entstehung regionalen Drogentrends einhergehen, erwiesen sich trotz mehrjährigem Bemühen als schwer fassbar, und einige hierzu in Großbritannien durchgeführte Studien waren mit erheblichen Problemen behaftet. Deshalb wurde vom "Drugs Analysis and Research Programme" und von "Market and Opinion Research International" (MORI) ein nationales Entwicklungsproje...

MITS Feed and Withdrawal Subsystem: operating procedures

International Nuclear Information System (INIS)

Brown, W.S.

1980-01-01

This document details procedures for the operation of the MITS (Machine Interface Test System) Feed and Withdrawal Subsystem (F and W). Included are fill with UF 6 , establishment of recycle and thruput flows, shutdown, UF 6 makeup, dump to supply container, Cascade dump to F and W, and lights cold trap dump, all normal procedures, plus an alternate procedure for trapping light gases

James Webb Space Telescope Optical Telescope Element Mirror Development History and Results

Science.gov (United States)

Feinber, Lee D.; Clampin, Mark; Keski-Kuha, Ritva; Atkinson, Charlie; Texter, Scott; Bergeland, Mark; Gallagher, Benjamin B.

2012-01-01

In a little under a decade, the James Webb Space Telescope (JWST) program has designed, manufactured, assembled and tested 21 flight beryllium mirrors for the James Webb Space Telescope Optical Telescope Element. This paper will summarize the mirror development history starting with the selection of beryllium as the mirror material and ending with the final test results. It will provide an overview of the technological roadmap and schedules and the key challenges that were overcome. It will also provide a summary or the key tests that were performed and the results of these tests.

Die Dramatikerin Theresia Walser spricht mit Maria Aparecida Barbosa über das Theaterstück »King Kongs Töchter«. Mit einer Einführung von Karina Schuller

Directory of Open Access Journals (Sweden)

Theresia Walser

2012-11-01

Full Text Available In ihrem Interview spricht die Literaturwissenschaftlerin Maria Aparecida Barbosa mit der Dramatikerin Theresia Walser. Am Beispiel des Theaterstücks King Kongs Töchter (1998, das sich auf groteske Art und Weise mit dem Alltag in einem Altenheim befasst, werden dabei verschiedene Themen angesprochen: Es geht um die Selbstreflexivität des Theaters, um Walsers Verständnis von poetischer Sprache und Realismus sowie um den kreativen Schreibprozess im Allgemeinen. Ergänzt wird das Interview durch eine Einführung von Karina Schuller.

Verbesserte Visualisierung der Koronararterien in MSCT-Daten mit direkter Vergleichbarkeit zur Angiographie

Science.gov (United States)

Lacalli, Christina; Jähne, Marion; Wesarg, Stefan

In diesem Beitrag stellen wir neue, automatisierte Verfahren zur Visualisierung der Koronararterien einerseits und für eine direkte Vergleichbarkeit mit konventionellen Angiogrammen andererseits vor. Unser Ansatz umfasst Methoden für die automatische Extraktion des Herzens aus kontrastverstärkten CT-Daten, sowie für die Maskierung grosser kontrastmittelgefüllter Kavitäten des Herzens, um die Sichtbarkeit der Koronararterien bei der Darstellung mittels Volumenrendering zu verbessern. Zum direkten Vergleich mit konventionellen Angiographien wurde ein Verfahren zur automatischen Generierung von Projektionsansichten aus den CT-Daten entwickelt.

Innovative facades with photovoltaics; Innovative Fassaden mit Photovoltaik

Energy Technology Data Exchange (ETDEWEB)

Eicker, U. [Hochschule fuer Technik, Stuttgart (Germany)

1999-10-01

Having grown at a rate of 15% since the middle of the 1980s the photovoltaic market today commands an annual module production of more than 100 MW{sub p}. In Germany altogether 10,000 PV systems with a total power output of 10 MW{sub p} were newly installed in 1997 alone. In 1990 the market was boosted by the heavily subsidised 1000 roofs programme, under which in the end more than 2,000 systems were installed on the roofs of mostly one-family houses. With power ratings ranging from 1 to 5 kW these decentral plants require roof surface areas between 10 and 50 m-2. On average they generate 800 kWh of electricity per kW of installed power. According to a number of studies carried out in the early 1990s the total surface area on buildings available for photovoltaics amounts to an enormous potential of 1,000 km-2, which is equivalent to an electricity generating potential of 130 TWh (100 TWh on roofs and 30 TWh on facades), or 25% of Germany`s total electricity demand. The degree to which this potential will be realised in the long term will notably depend on whether convincing architectural solutions are found for integrating photovoltaic plants in roofs and facades. [Deutsch] Der Photovoltaikmarkt waechst weltweit seit Mitte der 80er Jahre um durchschnittlich 15% und liegt heute bei einer Jahresmodulproduktion ueber 100 MW{sub p}. In Deutschland wurden alleine 1997 etwa 10.000 PV-Systeme mit einer Gesamtleistung von 10 MW{sub p} installiert. Die Marktentwicklung wurde 1990 mit dem stark subventionierten 1000-Daecher Programm angestossen, in welchem schliesslich mehr als 2000 Systeme meist auf Daechern von Einfamilienhaeusern installiert wurden. Diese dezentralen Anlagen mit Leistungen zwischen 1 und 5 kW erfordern Dachflaechen zwischen 10 und 50 m{sup 2} und erzeugen im Schnitt 800 kWh Strom pro kW installierter Leistung. Das verfuegbare Flaechenpotential von Gebaeuden wurde Anfang der 90er Jahre in einer Reihe von Studien ermittelt und stellt mit etwa 1000 km{sup 2

MIT Orients Course Materials Online to K-12

Science.gov (United States)

Cavanagh, Sean

2008-01-01

Many science and mathematics educators across the country are taking advantage of a Web site created by the Massachusetts Institute of Technology (MIT), the famed research university located in Cambridge, Massachusetts, which offers free video, audio, and print lectures and course material taken straight from the school's classes. Those resources…

Mechanical design of SST-GATE, a dual-mirror telescope for the Cherenkov Telescope Array

Science.gov (United States)

Dournaux, Jean-Laurent; Huet, Jean-Michel; Amans, Jean-Philippe; Dumas, Delphine; Laporte, Philippe; Sol, Hélène; Blake, Simon

2014-07-01

The Cherenkov Telescope Array (CTA) project aims to create the next generation Very High Energy (VHE) gamma-ray telescope array. It will be devoted to the observation of gamma rays over a wide band of energy, from a few tens of GeV to more than 100 TeV. Two sites are foreseen to view the whole sky where about 100 telescopes, composed of three different classes, related to the specific energy region to be investigated, will be installed. Among these, the Small Size class of Telescopes, SSTs, are devoted to the highest energy region, to beyond 100 TeV. Due to the large number of SSTs, their unit cost is an important parameter. At the Observatoire de Paris, we have designed a prototype of a Small Size Telescope named SST-GATE, based on the dual-mirror Schwarzschild-Couder optical formula, which has never before been implemented in the design of a telescope. Over the last two years, we developed a mechanical design for SST-GATE from the optical and preliminary mechanical designs made by the University of Durham. The integration of this telescope is currently in progress. Since the early stages of mechanical design of SST-GATE, finite element method has been used employing shape and topology optimization techniques to help design several elements of the telescope. This allowed optimization of the mechanical stiffness/mass ratio, leading to a lightweight and less expensive mechanical structure. These techniques and the resulting mechanical design are detailed in this paper. We will also describe the finite element analyses carried out to calculate the mechanical deformations and the stresses in the structure under observing and survival conditions.

MIT Clean Energy Prize: Final Technical Report May 12, 2010 - May 11, 2011

Energy Technology Data Exchange (ETDEWEB)

Snyder, Chris [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Campbell, Georgina [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Salony, Jason [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Aulet, Bill [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)

2011-08-09

The MIT Clean Energy Prize (MIT CEP) is a venture creation and innovation competition to encourage innovation in the energy space, specifically with regard to clean energy. The Competition invited student teams from any US university to submit student-led ventures that demonstrate a high potential of successfully making clean energy more affordable, with a positive impact on the environment. By focusing on student ventures, the MIT CEP aims to educate the next generation of clean energy entrepreneurs. Teams receive valuable mentoring and hard deadlines that complement the cash prize to accelerate development of ventures. The competition is a year-long educational process that culminates in the selection of five category finalists and a Grand Prize winner and the distribution of cash prizes to each of those teams. Each entry was submitted in one of five clean energy categories: Renewables, Clean Non-Renewables, Energy Efficiency, Transportation, and Deployment.

Neodadjuvante und adjuvante Kurzzeit-Hormontherapie in Kombination mit konformaler HDR-Brachytherapie beim Prostatakarzinom

Directory of Open Access Journals (Sweden)

Martin T

2004-01-01

Full Text Available Zielsetzung: Auswertung der Behandlungsergebnisse der neoadjuvanten und adjuvanten Kurzzeit-Hormontherapie kombiniert mit konformaler HDR-Brachytherapie und externer Radiotherapie beim Prostatakarzinom. Patienten und Methoden: Von 01/97 bis 09/99 behandelten wir 102 Patienten mit Prostatakarzinomen im Stadium T1–3 N0 M0. Im Stadium T1–2 befanden sich 71, im Stadium T3 31 Patienten. Der mediane prätherapeutische PSA-Wert betrug 15,3 ng/ml. Nach ultraschallgesteuerter transrektaler Implantation von vier Afterloadingnadeln erfolgte die CT-gestützte 3D-Brachytherapie- Planung. Alle Patienten erhielten vier HDR-Implantate mit einer Referenzdosis von 5 Gy oder 7 Gy pro Implantat. Die Zeit zwischen jedem Implantat betrug jeweils 14 Tage. Nach der Brachytherapie folgte die externe Radiotherapie bis 39,6 Gy oder 45,0 Gy. Alle Patienten erhielten eine neoadjuvante und adjuvante Kurzzeit-Hormontherapie, die 2–19 Monate vor der Brachytherapie eingeleitet und 3 Monate nach Abschluß der externen Radiotherapie abgesetzt wurde (mediane Dauer: 9 Monate. Ergebnisse: Die mediane Nachbeobachtungszeit war 2,6 Jahre (range: 2,0–4,1 Jahre. Die biochemische Kontrollrate betrug 82 % nach 3 Jahren. Bei 14/102 Patienten registrierten wir ein biochemisches Rezidiv, bei 5/102 Patienten ein klinisches Rezidiv. Das Gesamtüberleben betrug 90 %, das krankheitsspezifische Überleben 98,0 % nach 3 Jahren. Ein Patient entwickelte eine prostato-urethro-rektale Fistel als späte Grad 4-Toxizität. Akute Grad-3 Toxizitäten traten bei 4 %, späte Grad-3 Toxizitäten bei 5 % der Patienten auf. Schlußfolgerung: Die neoadjuvante und adjuvante Kurzzeit-Hormontherapie kombiniert mit konformaler HDR-Brachytherapie und externer Radiotherapie erweist sich als sichere und wirksame Behandlungsmodalität beim Prostatakarzinom mit minimalen behandlungsbedingten Toxizitäten und einer vielversprechenden biochemischen Kontrollrate nach medianer Nachbeobachtungszeit von 2,6 Jahren.

Crash tests with Smartcrash barriers, a technology with a future; Zukunftssichere Crashtests mit Smartcrash-Barrieren

Energy Technology Data Exchange (ETDEWEB)

Barz, D.; Evers, W. [Kistler Instrumente AG (Switzerland). Geschaeftsbereich Fahrzeugmesstechnik

2005-02-01

The Smartcrash barrier by Kistler is a completely new technology. State-of-the-art data processing with Microdau modules is combined with a singular mechanical modularity which meets all requirements of present and future crash standards. Together with a piezo measuring system perfectly tuned to the highly dynamic processes during crash tests, this provides a basis for making crash laboratories economically efficient, with safe and accurate data, and compatible with other measuring systems. The system is a 'must' for every modern crash laboratory. (orig.) [German] Die Smartcrash-Barriere von Kistler setzt in jeder Hinsicht Massstaebe. Neueste Technologie der Datenverarbeitung beim Crash mit Microdau-Modulen, wie sie auch in Dummys eingesetzt werden, wird mit einer einzigartigen mechanischen Modularitaet kombiniert, die alle erforderlichen Voraussetzungen fuer bestehende und zukuenftige Crash-Standards bietet. In Verbindung mit der fuer die Messung von hochdynamischen Kraftverlaeufen beim Crash praedestinierte Piezo-Messtechnik ist hiermit die Basis geschaffen, Crash-Laboratorien wirtschaftlich und hinsichtlich des Datenakquisition sicher und kompatibel mit anderen Messgroessen im Labor auszuruesten. Ein 'Muss' fuer jedes moderne Crash-Labor. (orig.)

Die Wirkung von Desacetylcefotaxin, einem Metaboliten von Cefotaxim, in vitro und auf die experimentelle Infektion mit Escherichia coli

OpenAIRE

Wirbelauer, J.; Hof, H.; Hacker, Jörg

2009-01-01

Die MHK-Werte von Desacetylcefotaxim gegen verschiedene, z. T. ampicillinresistente Stämme von Escherichia coH, die mit Hilfe einer Agardilutionsmethode erhoben wurden, waren höher als die von Cefotaxim und Ceftriaxon, jedoch niedriger als die von Cefoxitin. In einem Modell der systemischen Infektion der Maus mit einem plasmidtragenden, betalactamaseproduzierenden Stamm von E. coli führte die Therapie mit Desacetylcefotaxim zu einer starken Reduktion der Keime pro Leber. Im Vergleich zur Ther...

Freie Lerninhalte im Internet mit Studierenden recherchieren, kommentieren und kompilieren. Zur Gestaltung der online-Selbstlernangebote im hr-Funkkolleg Philosophie

Directory of Open Access Journals (Sweden)

Jakob Krebs

2017-03-01

Full Text Available Wie lassen sich online frei verfügbare Bildungsinhalte mit Studierenden so zusammenstellen, dass sie als thematisch sortierte Selbstlernmaterialien unkompliziert gefunden werden können – sei es von anderen Studierenden, interessierten Laien oder auch von Lehrkräften in Bildungsinstitutionen? Der vorliegende Werkstattbericht rekonstruiert ein Lernszenario, in dem Studierende vorhandene Materialien im Internet recherchierten, kommentierten und kompilierten, um ein Online-Zusatzangebot zu den Radiosendungen im hr-Funkkolleg Philosophie 2014/15 zu erstellen. Die Rahmenbedingungen dieser ungewöhnlichen universitären Kooperation mit dem Rundfunk werden im ersten Abschnitt vorgestellt. Der zweite Abschnitt skizziert das didaktische Design zusammen mit dem Projektstrukturplan eines produktorientierten kollaborativen Lernsettings mit Wiki-Einsatz. Im dritten Abschnitt werden der Lernerfolg bei den Studierenden sowie einige Herausforderungen benannt, die u. a. in der Abschlussevaluierung zur Sprache kamen. Der vierte Abschnitt macht die Projekterfahrungen für reguläre Lehr- und Lern-Szenarien fruchtbar, in denen nicht nur Studierende mit didaktischen Interessen durch die gemeinsame Gestaltung von Internetangeboten fachlich und methodisch profitieren können. Mit dem Bericht wird somit u. a. veranschaulicht, wie sich Ansätze von Blended, Peer-Assisted und Service Learning produktiv kombinieren lassen.

MIT wavelength tables. Volume 2. Wavelengths by element

International Nuclear Information System (INIS)

Phelps, F.M. III.

1982-01-01

This volume is the first stage of a project to expand and update the MIT wavelength tables first compiled in the 1930's. For 109,325 atomic emission lines, arranged by element, it presents wavelength in air, wavelength in vacuum, wave number and intensity. All data are stored on computer-readable magnetic tape

A metabolic signature for long life in the Caenorhabditis elegans Mit mutants.

Science.gov (United States)

Butler, Jeffrey A; Mishur, Robert J; Bhaskaran, Shylesh; Rea, Shane L

2013-02-01

Mit mutations that disrupt function of the mitochondrial electron transport chain can, inexplicably, prolong Caenorhabditis elegans lifespan. In this study we use a metabolomics approach to identify an ensemble of mitochondrial-derived α-ketoacids and α-hydroxyacids that are produced by long-lived Mit mutants but not by other long-lived mutants or by short-lived mitochondrial mutants. We show that accumulation of these compounds is dependent on concerted inhibition of three α-ketoacid dehydrogenases that share dihydrolipoamide dehydrogenase (DLD) as a common subunit, a protein previously linked in humans with increased risk of Alzheimer's disease. When the expression of DLD in wild-type animals was reduced using RNA interference we observed an unprecedented effect on lifespan - as RNAi dosage was increased lifespan was significantly shortened, but, at higher doses, it was significantly lengthened, suggesting that DLD plays a unique role in modulating length of life. Our findings provide novel insight into the origin of the Mit phenotype. © 2012 The Authors Aging Cell © 2012 Blackwell Publishing Ltd/Anatomical Society of Great Britain and Ireland.

InterCity tilting e.m.u. for Deutsche Bahn; InterCity-Triebzuege mit Neigetechnik fuer die Deutsche Bahn

Energy Technology Data Exchange (ETDEWEB)

Behmann, U.

1999-07-01

When changing time schedule in the end of may 1999 the German Railway (DB) starts with a new generation of electric intercity trains for 1 AC 15 kV 16 2/3 Hz. Five trains with tilt mechanism will travel between Stuttgart - Singen - Schaffhausen - Zurich. For this purpose these trains are equipped in addition with swiss current collectors and safety engineering. [German] Zum Fahrplanwechsel Ende Mai 1999 wird die Deutsche Bahn (DB) mit einer neuen Generation elektrischer InterCity-Triebzuege fuer 1 AC 15 kV 16 2/3 Hz in den kommerziellen Dienst gehen. Mit fuenf Zuegen Baureihe (BR) 415 mit Neigetechnik (ICT) wird sie die Relation Stuttgart - Singen - Schaffhausen - Zuerich bedienen. Dafuer wurden diese fuenf Zuege zusaetzlich mit schweizerischer Stromabnehmerwippe und Zugsicherungseinrichtung ausgeruestet. (orig/GL)

Nagelbefall kann bei Patienten mit Psoriasis auf eine Enthesiopathie hinweisen.

Science.gov (United States)

Castellanos-González, Maria; Joven, Beatriz Esther; Sánchez, Julio; Andrés-Esteban, Eva María; Vanaclocha-Sebastián, Francisco; Romero, Pablo Ortiz; Díaz, Raquel Rivera

2016-11-01

Obwohl subklinische Enthesiopathie ein gut etabliertes diagnostisches Merkmal der Psoriasisarthritis (PsA) ist, wird sie häufig übersehen, da viele Patienten asymptomatisch sind. Gäbe es klinische Hinweise auf das Vorliegen einer Enthesiopathie, würde dies den Klinikern die Möglichkeit eröffnen, eine PsA frühzeitig zu diagnostizieren. Es wurde eine monozentrische prospektive Studie mit insgesamt 90 Psoriasis-Patienten durchgeführt, um mittels Ultraschall das Vorliegen von Enthesenanomalien zu untersuchen und eine Korrelation mit dem Befall der Nägel festzustellen. Enthesenanomalien wurden bei 23 Patienten (25,5 %) gefunden, von denen 19 (82,6 %) Nagelbefall aufwiesen. Bei 4 Patienten waren die Nägel nicht betroffen. Enthesiopathie lag bei 31,1 % (19/61) der Patienten mit Onychopathie vor, von den Patienten ohne Nagelbefall litten nur 13,8 % (4/29) an Enthesiopathie (p = 0,07). Zwischen dem Target-NAPSI-Score und dem Vorliegen einer Enthesiopathie bestand eine signifikante Korrelation. Eine signifikante Korrelation bestand darüber hinaus auch zwischen dem Vorliegen einer Enthesiopathie und der Anzahl der betroffenen Nägel (p = 0,035). Klinische Belege für eine Onychopathie können der Schlüssel für die frühe Diagnose einer Enthesiopathie bei Psoriasis-Patienten sein. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

A Detailed Model Atmosphere Analysis of Cool White Dwarfs in the Sloan Digital Sky Survey

Science.gov (United States)

2010-09-01

and halo. Kleinman et al. (2004) and Eisenstein et al. (2006) have ∗ Based on observations obtained at the Hobby–Eberly Telescope (HET), Gemini...SDSS photometry is in the AB system. We use the corrections given in Eisenstein et al. (2006) for the u-, i-, and z-band photometry, and Table 1...Beers, T. C. 2000, AJ, 119, 2843 Dufour, P., Bergeron, P., & Fontaine, G. 2005, ApJ, 627, 404 Dufour, P., et al. 2007, ApJ, 663, 1291 Eisenstein , D

The first telescope of the HEGRA air Cherenkov imaging telescope array

International Nuclear Information System (INIS)

Mirzoyan, R.; Kankanian, R.; Krennrich, F.; Mueller, N.; Sander, H.; Sawallisch, P.; Aharonian, F.; Akhperjanian, A.; Beglarian, A.; Fernandez, J.; Fonseca, V.; Grewe, W.; Heusler, A.; Konopelko, A.K.; Lorenz, E.; Merck, M.; Plyasheshnikov, A.V.; Renker, D.; Samorski, M.; Sauerland, K.; Smarsch, E.; Stamm, W.; Ulrich, M.; Wiedner, C.A.; Wirth, H.

1994-01-01

In search of VHE γ ray emission from cosmic point sources a system of imaging Cherenkov telescopes is constructed at present on the Canarian island of La Palma; the first telescope has been operational since 1992. The Cherenkov light from air shower particles is collected by a 5 m 2 reflector. The camera at the focus contains 37 photomultipliers which sample the images of the Cherenkov flashes. The subsequent image analysis allows the discrimination of γ ray induced events from the much more abundant charged cosmic ray induced showers. The telescope has an effective energy threshold for γ showers of about 1.5 TeV. During the first year of operation a signal from the Crab nebula was detected. ((orig.))

MIT nuclear reactor laboratory high school teaching program

International Nuclear Information System (INIS)

Olmez, I.

1991-01-01

For the last 6 years, the Massachusetts Institute of Technology (MIT) Nuclear Reactor Laboratory's academic and scientific staff a have been conducting evening seminars for precollege science teachers, parents, and high school students from the New England area. These seminars, as outlined in this paper, are intended to give general information on nuclear technologies with specific emphasis on radiation physics, nuclear medicine, nuclear chemistry, and ongoing research activities at the MIT research reactor. The ultimate goal is to create interest or build on the already existing interest in science and technology by, for example, special student projects. Several small projects have already been completed ranging from environmental research to biological reactions with direct student involvement. Another outcome of these seminars was the change in attitudes of science teachers toward nuclear technology. Numerous letters have been received from the teachers and parents stating their previous lack of knowledge on the beneficial aspects of nuclear technologies and the subsequent inclusion of programs in their curriculum for educating students so that they may also develop a more positive attitude toward nuclear power

Material Identification Technology (MIT) concept technical feasibility study

International Nuclear Information System (INIS)

Jones, J.L.; Harker, Y.D.; Yoon, W.Y.; Johnson, L.O.

1993-09-01

The Idaho National Engineering Laboratory (INEL) has initiated the design and development of a novel pulsed accelerator-based, active interrogation concept. The proposed concept, referred to as the Material Identification Technology (MIT), enables rapid (between accelerator pulses), non-destructive, elemental composition analysis of both nuclear and non-nuclear materials. Applications of this technique include material monitoring in support of counter-proliferation activities, such as export controls (at domestic and international inspection locations), SNM controls, nuclear weapon dismantlement, and chemical weapon verification. Material Identification Technology combines a pulsed, X-ray source (an electron accelerator) and a gamma detection system. The accelerator must maximize neutron production (pulse width, beam current, beam energy, and repetition rate) and minimize photon dose to the object. Current available accelerator technology can meet these requirements. The detection system must include detectors which provide adequate gamma energy resolution capability, rapid recovery after the initial X-ray interrogation pulse, and multiple single gamma event detection between accelerator pulses. Further research is required to develop the detection system. This report provides the initial feasibility assessment of the MIT concept

First results of the Test-Bed Telescopes (TBT) project: Cebreros telescope commissioning

Science.gov (United States)

Ocaña, Francisco; Ibarra, Aitor; Racero, Elena; Montero, Ángel; Doubek, Jirí; Ruiz, Vicente

2016-07-01

The TBT project is being developed under ESA's General Studies and Technology Programme (GSTP), and shall implement a test-bed for the validation of an autonomous optical observing system in a realistic scenario within the Space Situational Awareness (SSA) programme of the European Space Agency (ESA). The goal of the project is to provide two fully robotic telescopes, which will serve as prototypes for development of a future network. The system consists of two telescopes, one in Spain and the second one in the Southern Hemisphere. The telescope is a fast astrograph with a large Field of View (FoV) of 2.5 x 2.5 square-degrees and a plate scale of 2.2 arcsec/pixel. The tube is mounted on a fast direct-drive mount moving with speed up to 20 degrees per second. The focal plane hosts a 2-port 4K x 4K back-illuminated CCD with readout speeds up to 1MHz per port. All these characteristics ensure good survey performance for transients and fast moving objects. Detection software and hardware are optimised for the detection of NEOs and objects in high Earth orbits (objects moving from 0.1-40 arcsec/second). Nominal exposures are in the range from 2 to 30 seconds, depending on the observational strategy. Part of the validation scenario involves the scheduling concept integrated in the robotic operations for both sensors. Every night it takes all the input needed and prepares a schedule following predefined rules allocating tasks for the telescopes. Telescopes are managed by RTS2 control software, that performs the real-time scheduling of the observation and manages all the devices at the observatory.1 At the end of the night the observing systems report astrometric positions and photometry of the objects detected. The first telescope was installed in Cebreros Satellite Tracking Station in mid-2015. It is currently in the commissioning phase and we present here the first results of the telescope. We evaluate the site characteristics and the performance of the TBT Cebreros

MITR-III: Upgrade and relicensing studies for the MIT Research Reactor. Second annual report

International Nuclear Information System (INIS)

Trosman, H.G.; Lanning, D.D.; Harling, O.K.

1994-08-01

The current operating license of the MIT research reactor will expire on May 7, 1996 or possibly a few years later if the US Nuclear Regulatory Commission agrees that the license period can start with the date of initial reactor operation. Driven by the imminent expiration of the operating license, a team of nuclear engineering staff and students have begun a study of the future options for the MIT Research Reactor. These options have included the range from a major rebuilding of the reactor to its decommissioning. This document reports the results of a two year intensive activity which has been supported by a $148,000 grant from the USDOE contract Number DEFG0293ER75859, approximately $100,000 of internal MIT funds and Nuclear Engineering Department graduate student fellowships as well as assistance from international visiting scientists and engineers

An Approach for Prevention of MitM Attack Based on Rogue AP in Wireless Network

Directory of Open Access Journals (Sweden)

Zhendong Wu

2014-12-01

Full Text Available With the rapid development of WLAN, more and more schools and businesses have begun to provide the WLAN for users. However, WLAN is considerably more susceptible to MitM (man- in-the-middle attack. To overcome it, we propose a dynamic password technology named Two-way Dynamic Authentication Technology (TDAT. It uses two-factor during the initial authentication, and uses a two-way hash chain during the cross-domain authentication. TDAT effectively protects users' authentication credentials and improves users' experience. In an actual wireless network environment, we implement a MitM attack framework based on Rogue AP. Then we effectively prevent this MitM attack by using TDAT. Moreover we analyze the security of TDAT by using BAN logic.

Interaktion mit virtuellen Agenten? Zur Aneignung eines ungewohnten Artefakts

DEFF Research Database (Denmark)

Krummheuer, Antonia Lina

sprechen, schließt der soziologische Interaktionsbegriff nichtmenschliche Gesprächspartner aus. Es stellt sich daher die Frage, mit welchen Konzepten die Soziologie dieses neue Phänomen fassen kann. Vor dem Hintergrund der techniksoziologischen Debatte um die Handlungsträgerschaft von Artefakten werden die...

Infrared up-conversion telescope

DEFF Research Database (Denmark)

2014-01-01

There is presented to an up-conversion infrared telescope (110) arranged for imaging an associated scene (130), wherein the up-conversion infrared telescope (110) comprises a non-linear crystal (120) arranged for up-conversion of infrared electromagnetic radiation, and wherein a first optical...

Untersuchungen zum Potential eines Verbrennungsmotors mit Druckwellenlader

OpenAIRE

Binder, Emanuel

2015-01-01

Mithilfe der Abgasturboaufladung lässt sich der Kraftstoffverbrauch im Fahrzeugbetrieb durch das Anheben der spezifischen Motorleistung senken. Im Gegensatz zur mechanischen Aufladung verschlechtert sich jedoch mit der Abgasturbolaufladung das Ansprechverhalten. Eine Möglichkeit den Zielkonflikt von Kraftstoffverbrauch und Ansprechverhalten zu lösen ist es, den Abgasturbolader durch einen Druckwellenladers zu ersetzen. Dieser überträgt die Abgasenergie direkt auf die Frischluft in Form von Dr...

Psychologie - Fachdatenbank mit europäischem Fokus

OpenAIRE

Schön, Dana

2010-01-01

Die Sichtbarkeit von europäischer Wissenschaftsliteratur ist notwendige Voraussetzung für deren Rezeption im internationalen Kontext. Ein bibliographisches Nachweissystem psychologischer Fachliteratur auf der Basis moderner Suchtechnologie mit Fokus auf europäischen Werken kann einen wichtigen Beitrag dazu leisten. Mehrere europäische Institute stellen ihre bibliographischen Datenbestände zum Aufbau einer umfassenden europäischen Fachdatenbank für die Psychologie zur Verfügung. Die Bereitstel...

Parametric cost models for space telescopes

Science.gov (United States)

Stahl, H. Philip; Henrichs, Todd; Dollinger, Courtnay

2017-11-01

Multivariable parametric cost models for space telescopes provide several benefits to designers and space system project managers. They identify major architectural cost drivers and allow high-level design trades. They enable cost-benefit analysis for technology development investment. And, they provide a basis for estimating total project cost. A survey of historical models found that there is no definitive space telescope cost model. In fact, published models vary greatly [1]. Thus, there is a need for parametric space telescopes cost models. An effort is underway to develop single variable [2] and multi-variable [3] parametric space telescope cost models based on the latest available data and applying rigorous analytical techniques. Specific cost estimating relationships (CERs) have been developed which show that aperture diameter is the primary cost driver for large space telescopes; technology development as a function of time reduces cost at the rate of 50% per 17 years; it costs less per square meter of collecting aperture to build a large telescope than a small telescope; and increasing mass reduces cost.

Parametric Cost Models for Space Telescopes

Science.gov (United States)

Stahl, H. Philip; Henrichs, Todd; Dollinger, Courtney

2010-01-01

Multivariable parametric cost models for space telescopes provide several benefits to designers and space system project managers. They identify major architectural cost drivers and allow high-level design trades. They enable cost-benefit analysis for technology development investment. And, they provide a basis for estimating total project cost. A survey of historical models found that there is no definitive space telescope cost model. In fact, published models vary greatly [1]. Thus, there is a need for parametric space telescopes cost models. An effort is underway to develop single variable [2] and multi-variable [3] parametric space telescope cost models based on the latest available data and applying rigorous analytical techniques. Specific cost estimating relationships (CERs) have been developed which show that aperture diameter is the primary cost driver for large space telescopes; technology development as a function of time reduces cost at the rate of 50% per 17 years; it costs less per square meter of collecting aperture to build a large telescope than a small telescope; and increasing mass reduces cost.

Insight into the adsorption profiles of the Saprolegnia monoica chitin synthase MIT domain on POPA and POPC membranes by molecular dynamics simulation studies.

Science.gov (United States)

Kuang, Guanglin; Liang, Lijun; Brown, Christian; Wang, Qi; Bulone, Vincent; Tu, Yaoquan

2016-02-21

The critical role of chitin synthases in oomycete hyphal tip growth has been established. A microtubule interacting and trafficking (MIT) domain was discovered in the chitin synthases of the oomycete model organism, Saprolegnia monoica. MIT domains have been identified in diverse proteins and may play a role in intracellular trafficking. The structure of the Saprolegnia monoica chitin synthase 1 (SmChs1) MIT domain has been recently determined by our group. However, although our in vitro assay identified increased strength in interactions between the MIT domain and phosphatidic acid (PA) relative to other phospholipids including phosphatidylcholine (PC), the mechanism used by the MIT domain remains unknown. In this work, the adsorption behavior of the SmChs1 MIT domain on POPA and POPC membranes was systematically investigated by molecular dynamics simulations. Our results indicate that the MIT domain can adsorb onto the tested membranes in varying orientations. Interestingly, due to the specific interactions between MIT residues and lipid molecules, the binding affinity to the POPA membrane is much higher than that to the POPC membrane. A binding hotspot, which is critical for the adsorption of the MIT domain onto the POPA membrane, was also identified. The lower binding affinity to the POPC membrane can be attributed to the self-saturated membrane surface, which is unfavorable for hydrogen-bond and electrostatic interactions. The present study provides insight into the adsorption profile of SmChs1 and additionally has the potential to improve our understanding of other proteins containing MIT domains.

A phase-I clinical trial for cranial BNCT at Harvard-MIT

International Nuclear Information System (INIS)

Busse, P.M.; Palmer, M.R.; Harling, O.K.

2000-01-01

Phase I trial designed to determine the maximum tolerable dose to normal tissue for cranial BNCT (Boron Neutron Capture Therapy) irradiations was recently completed at Harvard Medical School and MIT. Twenty-two subjects diagnosed with either glioblastoma multiforme or intracranial melanoma were treated between 1996 and 1999. Subjects received either one or two administrations of boronophenylalanine intravenously at doses between 250 and 350 mg/kg body weight, then exposed in one, two or three fields to epithermal neutrons at the MIT Research Reactor in one or two fractions. Over the course of the study, the maximum normal tissue dose target was increased from 8.8 to 14.2 RBE (Relative Biological Effectiveness) Gy in 10% increments. Subjects have been followed clinically and radiographically. Of those patients surviving beyond six months, no MRI (Magnetic Resonance Image) white-matter changes were observed and no long-term complications attributable to BNCT were evident. Tumor responses were observed, particularly with the melanoma subjects. With increasing doses, difficulties arose from long irradiation times (approximately 3 hours) and the emergence of acute reactions in the skin and mucosa. The trial was stopped in May 1999. Future trials will be initiated with the new high intensity, low background fission converter beam at MIT. (author)

Natural gas engine concept with EZEV potential; Erdgasmotorkonzept mit EZEV-Potential

Energy Technology Data Exchange (ETDEWEB)

Maier, F.; Mueller, P.; Heck, E.; Langen, P. [BMW AG (Germany)

1997-09-01

The first natural gas vehicles form BMW are designed for arbitrary gasoline or natural gas operation. It is possible only to a limited extent to take advantage of the benefits of natural gas as a fuel as long as this is the case. An analysis was made to determine possible improvements in terms of fuel economy, emissions, full load and maximum exhaust gas temperatures through selective optimisation for exclusive natural gas operation. The results of this analysis have been used in the design of natural gas engines for mid-sized vehicles. Vehicle examinations in FTP75 confirm the existing potential for satisfying EZEV standards discussed in California even with vehicles of the upper midsize category by using optimised natural gas engines. (orig.) [Deutsch] Die ersten Automobile mit Erdgasantrieb von BMW sind fuer den wahlweisen Benzin- oder Erdgasbetrieb ausgelegt. Deshalb koennen die Vorteile des Kraftstoffs Erdgas nur zum Teil genutzt werden. Es wurde untersucht, welche Verbesserungen durch gezielte Optimierung fuer den ausschliesslichen Erdgasbetrieb bei Kraftstoffverbrauch, Emissionen, Vollast und maximalen Abgastemperaturen moeglich sind. Die Ergebnisse wurden bei der Auslegung von Erdgasmotoren fuer Mittelklassefahrzeuge verwendet. Untersuchungen im FTP-75 bestaetigen, dass mit optimierten Erdgasmotoren das Potential besteht, selbst mit Automobilen der oberen Mittelklasse die in Kalifornien diskutierten EZEV-Standards zu erfuellen. (orig.)

Development of a mid-sized Schwarzschild-Couder Telescope for the Cherenkov Telescope Array

Energy Technology Data Exchange (ETDEWEB)

Cameron, Robert A.

2012-06-28

The Cherenkov Telescope Array (CTA) is a ground-based observatory for very high-energy (10 GeV to 100 TeV) gamma rays, planned for operation starting in 2018. It will be an array of dozens of optical telescopes, known as Atmospheric Cherenkov Telescopes (ACTs), of 8 m to 24 m diameter, deployed over an area of more than 1 square km, to detect flashes of Cherenkov light from showers initiated in the Earth's atmosphere by gamma rays. CTA will have improved angular resolution, a wider energy range, larger fields of view and an order of magnitude improvement in sensitivity over current ACT arrays such as H.E.S.S., MAGIC and VERITAS. Several institutions have proposed a research and development program to eventually contribute 36 medium-sized telescopes (9 m to 12 m diameter) to CTA to enhance and optimize its science performance. The program aims to construct a prototype of an innovative, Schwarzschild-Couder telescope (SCT) design that will allow much smaller and less expensive cameras and much larger fields of view than conventional Davies-Cotton designs, and will also include design and testing of camera electronics for the necessary advances in performance, reliability and cost. We report on the progress of the mid-sized SCT development program.

A telescope with augmented reality functions

Science.gov (United States)

Hou, Qichao; Cheng, Dewen; Wang, Qiwei; Wang, Yongtian

2016-10-01

This study introduces a telescope with virtual reality (VR) and augmented reality (AR) functions. In this telescope, information on the micro-display screen is integrated to the reticule of telescope through a beam splitter and is then received by the observer. The design and analysis of telescope optical system with AR and VR ability is accomplished and the opto-mechanical structure is designed. Finally, a proof-of-concept prototype is fabricated and demonstrated. The telescope has an exit pupil diameter of 6 mm at an eye relief of 19 mm, 6° field of view, 5 to 8 times visual magnification , and a 30° field of view of the virtual image.

The Gemini 8-Meter Telescopes Project

Science.gov (United States)

Boroson, Todd A.

1995-05-01

The Gemini 8-Meter Telescopes Project is an international partnership to build and operate two 8-meter telescopes, one on Mauna Kea, Hawaii, and one on Cerro Pachon, Chile. The telescopes will be international facilities, open to the scientific communities of the six member countries, the United States (50%), the United Kingdom (25%), Canada (15%), Chile (5%), Argentina (2.5%), and Brazil (2.5%). The telescopes are designed to exploit the best atmospheric conditions at these excellent sites. Near diffraction limited performance will be delivered at 2.2 microns and longward, with minimal degradation of the best seeing conditions at shorter wavelengths. The telescopes and facilities are designed to achieve emissivity opportunity. First light for the Mauna Kea telescope is expected in late 1998, and for the Cerro Pachon telescope in mid-2000. This talk will report on construction progress, the instrumental capabilities, and operations strategies being considered. The Gemini 8-meter Telescopes Project is managed by the Association of Universities for Research in Astronomy (AURA), Inc. under a cooperative agreement with the National Science Foundation which serves as executive agency for the Gemini partner countries. U.S. participation in the project is through the U.S. Gemini Program, a division of the National Optical Astronomy Observatories. NOAO is operated by AURA, Inc. under cooperative agreement with the National Science Foundation.

Validation of the Omron MIT Elite blood pressure device in a pregnant population with large arm circumference.

Science.gov (United States)

James, Lauren; Nzelu, Diane; Hay, Anna; Shennan, Andrew; Kametas, Nikos A

2017-04-01

The aim of this study was to evaluate the accuracy of the Omron MIT Elite automated device in pregnant women with an arm circumference of or above 32 cm, using the British Hypertension Society validation protocol. Blood pressure was measured sequentially in 46 women of any gestation requiring the use of a large cuff (arm circumference ≥32 cm) alternating between the mercury sphygmomanometer and the Omron MIT Elite device. The Omron MIT Elite achieved an overall D/D grade with a mean of the device-observer difference being 7.17±6.67 and 9.31±6.59 for systolic and diastolic blood pressure respectively. Interobserver accuracy was 94.6% for systolic and 95% for diastolic readings within 5 mmHg. The Omron MIT Elite overestimates blood pressure and has failed the British Hypertension Society protocol requirements. Therefore, it cannot be recommended for use in pregnant women with an arm circumference of or above 32 cm.

Pre-selecting muon events in the camera server of the ASTRI telescopes for the Cherenkov Telescope Array

Science.gov (United States)

Maccarone, Maria C.; Mineo, Teresa; Capalbi, Milvia; Conforti, Vito; Coffaro, Martina

2016-08-01

The Cherenkov Telescope Array (CTA) represents the next generation of ground based observatories for very high energy gamma ray astronomy. The CTA will consist of two arrays at two different sites, one in the northern and one in the southern hemisphere. The current CTA design foresees, in the southern site, the installation of many tens of imaging atmospheric Cherenkov telescopes of three different classes, namely large, medium, and small, so defined in relation to their mirror area; the northern hemisphere array would consist of few tens of the two larger telescope types. The telescopes will be equipped with cameras composed either of photomultipliers or silicon photomultipliers, and with different trigger and read-out electronics. In such a scenario, several different methods will be used for the telescopes' calibration. Nevertheless, the optical throughput of any CTA telescope, independently of its type, can be calibrated analyzing the characteristic image produced by local atmospheric highly energetic muons that induce the emission of Cherenkov light which is imaged as a ring onto the focal plane if their impact point is relatively close to the telescope optical axis. Large sized telescopes would be able to detect useful muon events under stereo coincidence and such stereo muon events will be directly addressed to the central CTA array data acquisition pipeline to be analyzed. For the medium and small sized telescopes, due to their smaller mirror area and large inter-telescope distance, the stereo coincidence rate will tend to zero; nevertheless, muon events will be detected by single telescopes that must therefore be able to identify them as possible useful calibration candidates, even if no stereo coincidence is available. This is the case for the ASTRI telescopes, proposed as pre-production units of the small size array of the CTA, which are able to detect muon events during regular data taking without requiring any dedicated trigger. We present two fast

Strategien zur HLA-Typisierung mit PyrosequencingTM

OpenAIRE

Entz, Patricia

2006-01-01

Der Haupthistokompatibilitätskomplex ist durch seine biologische Funktion eine für die Diagnostik und Forschung äußerst wichtige Region im humanen Genom. Die Untersuchung von HLA-Genorten stellt ein wichtiges Instrument in der molekulargenetischen Praxis dar. Die Pyrosequencing-Technik ist gut geeignet, um kurze DNA-Abschnitte mit weitgehend bekannter Sequenz schnell und effizient zu untersuchen. Ziel dieser Arbeit war die Entwicklung von Pyrosequencing-basierten Methoden zur HLA-Typisierung....

Virtuelle Auskunft mit Mehrwert : Chatbots in Bibliotheken

OpenAIRE

Christensen, Anne

2008-01-01

Die virtuelle Auskunft mit Hilfe elektronischer Informationsassistenten, auch Chatbots oder Chatterbots genannt, ist ein seit dem Jahr 2004 zu beobachtender Trend im deutschen Bibliothekswesen. Die Arbeit stellt die vier Chatbots ASKademicus, Stella, INA und das Sachsen-I vor. Am Beispiel von Stella aus der SUB Hamburg werden dann die Funktionsweise von Chatbots sowie die Anforderungen an die Konzeption dieser virtuellen Berater erläutert. Den Schwerpunkt der Arbeit bilden der Vergleich von C...

Cost Modeling for Space Telescope

Science.gov (United States)

Stahl, H. Philip

2011-01-01

Parametric cost models are an important tool for planning missions, compare concepts and justify technology investments. This paper presents on-going efforts to develop single variable and multi-variable cost models for space telescope optical telescope assembly (OTA). These models are based on data collected from historical space telescope missions. Standard statistical methods are used to derive CERs for OTA cost versus aperture diameter and mass. The results are compared with previously published models.

THE PTF ORION PROJECT: A POSSIBLE PLANET TRANSITING A T-TAURI STAR

Energy Technology Data Exchange (ETDEWEB)

Van Eyken, Julian C.; Ciardi, David R.; Von Braun, Kaspar; Kane, Stephen R.; Plavchan, Peter; Akeson, Rachel L.; Beichman, Charles A.; Gelino, Dawn M. [NASA Exoplanet Science Institute, California Institute of Technology, 770 South Wilson Avenue, M/S 100-22, Pasadena, CA 91125 (United States); Bender, Chad F.; Mahadevan, Suvrath [Department of Astronomy and Astrophysics, The Pennsylvania State University, University Park, PA 16802 (United States); Brown, Timothy M.; Fulton, Benjamin J.; Shporer, Avi [Las Cumbres Observatory Global Telescope, Goleta, CA 93117 (United States); Crepp, Justin R. [Cahill Center for Astrophysics, California Institute of Technology, Pasadena, CA 91125 (United States); Howard, Andrew W.; Marcy, Geoffrey W. [Department of Astronomy, University of California, Berkeley, CA 94720-3411 (United States); Howell, Steve B. [NASA Ames Research Center, M/S 244-30, Moffett Field, CA 94035 (United States); Szkody, Paula [Department of Astronomy, University of Washington, Box 351580, Seattle, WA 98195 (United States); Boden, Andrew F. [Caltech Optical Observatories, California Institute of Technology, Pasadena, CA 91125 (United States); Hoard, D. W., E-mail: vaneyken@ipac.caltech.edu [Spitzer Science Center, M/S 220-6, California Institute of Technology, Jet Propulsion Laboratory, Pasadena, CA 91125 (United States); and others

2012-08-10

We report observations of a possible young transiting planet orbiting a previously known weak-lined T-Tauri star in the 7-10 Myr old Orion-OB1a/25-Ori region. The candidate was found as part of the Palomar Transient Factory (PTF) Orion project. It has a photometric transit period of 0.448413 {+-} 0.000040 days, and appears in both 2009 and 2010 PTF data. Follow-up low-precision radial velocity (RV) observations and adaptive optics imaging suggest that the star is not an eclipsing binary, and that it is unlikely that a background source is blended with the target and mimicking the observed transit. RV observations with the Hobby-Eberly and Keck telescopes yield an RV that has the same period as the photometric event, but is offset in phase from the transit center by Almost-Equal-To - 0.22 periods. The amplitude (half range) of the RV variations is 2.4 km s{sup -1} and is comparable with the expected RV amplitude that stellar spots could induce. The RV curve is likely dominated by stellar spot modulation and provides an upper limit to the projected companion mass of M{sub p}sin i{sub orb} {approx}< 4.8 {+-} 1.2 M{sub Jup}; when combined with the orbital inclination, i{sub orb}, of the candidate planet from modeling of the transit light curve, we find an upper limit on the mass of the planetary candidate of M{sub p} {approx}< 5.5 {+-} 1.4 M{sub Jup}. This limit implies that the planet is orbiting close to, if not inside, its Roche limiting orbital radius, so that it may be undergoing active mass loss and evaporation.

A SURVEY OF ALKALI LINE ABSORPTION IN EXOPLANETARY ATMOSPHERES

International Nuclear Information System (INIS)

Jensen, Adam G.; Redfield, Seth; Endl, Michael; Cochran, William D.; Koesterke, Lars; Barman, Travis S.

2011-01-01

We obtained over 90 hr of spectroscopic observations of four exoplanetary systems with the Hobby-Eberly Telescope. Observations were taken in transit and out of transit, and we analyzed the differenced spectra—i.e., the transmission spectra—to inspect it for absorption at the wavelengths of the neutral sodium (Na I) doublet at λλ5889, 5895 and neutral potassium (K I) at λ7698. We used the transmission spectrum at Ca I λ6122—which shows strong stellar absorption but is not an alkali metal resonance line that we expect to show significant absorption in these atmospheres—as a control line to examine our measurements for systematic errors. We use an empirical Monte Carlo method to quantify these systematic errors. In a reanalysis of the same data set using a reduction and analysis pipeline that was derived independently, we confirm the previously seen Na I absorption in HD 189733b at a level of (– 5.26 ± 1.69) × 10 –4 (the average value over a 12 Å integration band to be consistent with previous authors). Additionally, we tentatively confirm the Na I absorption seen in HD 209458b (independently by multiple authors) at a level of (– 2.63 ± 0.81) × 10 –4 , though the interpretation is less clear. Furthermore, we find Na I absorption of (– 3.16 ± 2.06) × 10 –4 at <3σ in HD 149026b; features apparent in the transmission spectrum are consistent with real absorption and indicate this may be a good target for future observations to confirm. No other results (Na I in HD 147506b and Ca I and K I in all four targets) are significant to ≥3σ, although we observe some features that we argue are primarily artifacts.

DISCOVERY OF A LARGE NUMBER OF CANDIDATE PROTOCLUSTERS TRACED BY ∼15 Mpc-SCALE GALAXY OVERDENSITIES IN COSMOS

International Nuclear Information System (INIS)

Chiang, Yi-Kuan; Gebhardt, Karl; Overzier, Roderik

2014-01-01

To demonstrate the feasibility of studying the epoch of massive galaxy cluster formation in a more systematic manner using current and future galaxy surveys, we report the discovery of a large sample of protocluster candidates in the 1.62 deg 2 COSMOS/UltraVISTA field traced by optical/infrared selected galaxies using photometric redshifts. By comparing properly smoothed three-dimensional galaxy density maps of the observations and a set of matched simulations incorporating the dominant observational effects (galaxy selection and photometric redshift uncertainties), we first confirm that the observed ∼15 comoving Mpc-scale galaxy clustering is consistent with ΛCDM models. Using further the relation between high-z overdensity and the present day cluster mass calibrated in these matched simulations, we found 36 candidate structures at 1.6 < z < 3.1, showing overdensities consistent with the progenitors of M z = 0 ∼ 10 15 M ☉ clusters. Taking into account the significant upward scattering of lower mass structures, the probabilities for the candidates to have at least M z= 0 ∼ 10 14 M ☉ are ∼70%. For each structure, about 15%-40% of photometric galaxy candidates are expected to be true protocluster members that will merge into a cluster-scale halo by z = 0. With solely photometric redshifts, we successfully rediscover two spectroscopically confirmed structures in this field, suggesting that our algorithm is robust. This work generates a large sample of uniformly selected protocluster candidates, providing rich targets for spectroscopic follow-up and subsequent studies of cluster formation. Meanwhile, it demonstrates the potential for probing early cluster formation with upcoming redshift surveys such as the Hobby-Eberly Telescope Dark Energy Experiment and the Subaru Prime Focus Spectrograph survey

Wide Field Infrared Survey Telescope [WFIRST]: telescope design and simulated performance

Science.gov (United States)

Goullioud, R.; Content, D. A.; Kuan, G. M.; Moore, J. D.; Chang, Z.; Sunada, E. T.; Villalvazo, J.; Hawk, J. P.; Armani, N. V.; Johnson, E. L.; Powell, C. A.

2012-09-01

The Wide Field Infrared Survey Telescope (WFIRST) mission concept was ranked first in new space astrophysics missions by the Astro2010 Decadal Survey, incorporating the Joint Dark Energy Mission payload concept and multiple science white papers. This mission is based on a space telescope at L2 studying exoplanets [via gravitational microlensing], probing dark energy, and surveying the near infrared sky. Since the release of the Astro2010 Decadal Survey, the team has been working with the WFIRST Science Definition Team to refine mission and payload concepts. We present the current interim reference mission point design of the payload, based on the use of a 1.3m unobscured aperture three mirror anastigmat form, with focal imaging and slit-less spectroscopy science channels. We also present the first results of Structural/Thermal/Optical performance modeling of the telescope point design.

Hartman Testing of X-Ray Telescopes

Science.gov (United States)

Saha, Timo T.; Biskasch, Michael; Zhang, William W.

2013-01-01

Hartmann testing of x-ray telescopes is a simple test method to retrieve and analyze alignment errors and low-order circumferential errors of x-ray telescopes and their components. A narrow slit is scanned along the circumference of the telescope in front of the mirror and the centroids of the images are calculated. From the centroid data, alignment errors, radius variation errors, and cone-angle variation errors can be calculated. Mean cone angle, mean radial height (average radius), and the focal length of the telescope can also be estimated if the centroid data is measured at multiple focal plane locations. In this paper we present the basic equations that are used in the analysis process. These equations can be applied to full circumference or segmented x-ray telescopes. We use the Optical Surface Analysis Code (OSAC) to model a segmented x-ray telescope and show that the derived equations and accompanying analysis retrieves the alignment errors and low order circumferential errors accurately.

SCIENTIFIC EFFICIENCY OF GROUND-BASED TELESCOPES

International Nuclear Information System (INIS)

Abt, Helmut A.

2012-01-01

I scanned the six major astronomical journals of 2008 for all 1589 papers that are based on new data obtained from ground-based optical/IR telescopes worldwide. Then I collected data on numbers of papers, citations to them in 3+ years, the most-cited papers, and annual operating costs. These data are assigned to four groups by telescope aperture. For instance, while the papers from telescopes with an aperture >7 m average 1.29 more citations than those with an aperture of 2 to 7 m) telescopes. I wonder why the large telescopes do so relatively poorly and suggest possible reasons. I also found that papers based on archival data, such as the Sloan Digital Sky Survey, produce 10.6% as many papers and 20.6% as many citations as those based on new data. Also, the 577.2 papers based on radio data produced 36.3% as many papers and 33.6% as many citations as the 1589 papers based on optical/IR telescopes.

Kompressionstherapie - Versorgungspraxis: Informationsstand von Patienten mit Ulcus cruris venosum.

Science.gov (United States)

Protz, Kerstin; Heyer, Kristina; Dissemond, Joachim; Temme, Barbara; Münter, Karl-Christian; Verheyen-Cronau, Ida; Klose, Katharina; Hampel-Kalthoff, Carsten; Augustin, Matthias

2016-12-01

Eine Säule der kausalen Therapie bei Patienten mit Ulcus cruris venosum ist die Kompressionstherapie. Sie unterstützt die Abheilung, reduziert Schmerzen und Rezidive und steigert die Lebensqualität. Bislang existieren kaum wissenschaftliche Daten zu dem Versorgungsstand und fachspezifischem Wissen von Patienten mit Ulcus cruris venosum. Standardisierte Fragebögen wurden bundesweit in 55 Pflegediensten, 32 Arztpraxen, vier Wundzentren und -sprechstunden sowie einem Pflegetherapiestützpunkt von Patienten mit Ulcus cruris venosum bei Erstvorstellung anonym ausgefüllt. Insgesamt nahmen 177 Patienten (Durchschnittsalter 69,4 Jahre; 75,1 % Frauen) teil. Ein florides Ulcus cruris venosum bestand im Mittel 17 Monate. 31,1 % hatten keine Kompressionstherapie, 40,1 % Binden und 28,8 % Strümpfe. Bei der Bestrumpfung hatten 13,7 % Kompressionsklasse III, 64,7 % Kompressionsklasse II und 19,6 % Kompressionsklasse I. 70,6 % legten die Strümpfe nach dem Aufstehen an, 21,1 % trugen sie Tag und Nacht. 39,2 % bereiteten die Strümpfe Beschwerden. Lediglich 11,7 % hatten eine An- und Ausziehhilfe. Die Binden wurden im Mittel 40,7 Wochen getragen und bei 69 % nicht unterpolstert. Bei 2,8 % wurde der Knöchel- und Waden-Umfang zur Erfolgskontrolle gemessen. Venensport machten 45,9 %. Ein Drittel hatte keine Kompressionsversorgung, obwohl diese eine Basismaßnahme der Therapie des Ulcus cruris venosum ist. Zudem ist deren korrekte Auswahl und Anwendung angesichts der langen Bestandsdauer der Ulzerationen zu hinterfragen. Weiterführende Fachkenntnisse bei Anwendern und Verordnern sowie Patientenschulungen sind erforderlich. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

Robotic and Survey Telescopes

Science.gov (United States)

Woźniak, Przemysław

Robotic telescopes are revolutionizing the way astronomers collect their dataand conduct sky surveys. This chapter begins with a discussion of principles thatguide the process of designing, constructing, and operating telescopes andobservatories that offer a varying degree of automation, from instruments remotelycontrolled by observers to fully autonomous systems requiring no humansupervision during their normal operations. Emphasis is placed on designtrade-offs involved in building end-to-end systems intended for a wide range ofscience applications. The second part of the chapter contains descriptions ofseveral projects and instruments, both existing and currently under development.It is an attempt to provide a representative selection of actual systems thatillustrates state of the art in technology, as well as important ideas and milestonesin the development of the field. The list of presented instruments spans the fullrange in size starting from small all-sky monitors, through midrange robotic andsurvey telescopes, and finishing with large robotic instruments and surveys.Explosive growth of telescope networking is enabling entirely new modesof interaction between the survey and follow-up observing. Increasingimportance of standardized communication protocols and software is stressed.These developments are driven by the fusion of robotic telescope hardware,massive storage and databases, real-time knowledge extraction, and datacross-correlation on a global scale. The chapter concludes with examplesof major science results enabled by these new technologies and futureprospects.

Amateur Telescope Making

Science.gov (United States)

Tonkin, Stephen

Many amateur astronomers make their own instruments, either because of financial considerations or because they are just interested. Amateur Telescope Making offers a variety of designs for telescopes, mounts and drives which are suitable for the home-constructor. The designs range from simple to advanced, but all are within the range of a moderately well-equipped home workshop. The book not only tells the reader what he can construct, but also what it is sensible to construct given what time is available commercially. Thus each chapter begins with reasons for undertaking the project, then looks at theoretical consideration before finishing with practical instructions and advice. An indication is given as to the skills required for the various projects. Appendices list reputable sources of (mail order) materials and components. The telescopes and mounts range from "shoestring" (very cheap) instruments to specialist devices that are unavailable commercially.

Review of lunar telescope studies at MSFC

Science.gov (United States)

Hilchey, John D.; Nein, Max E.

1993-09-01

In the near future astronomers can take advantage of the lunar surface as the new 'high ground' from which to study the universe. Optical telescopes placed and operated on the lunar surface would be successors to NASA's Great Observatories. Four telescopes, ranging in aperture from a 16-m, IR/Vis/UV observatory down to a 1-m, UV 'transit' instrument, have been studied by the Lunar Telescope Working Group and the LUTE (lunar telescope ultraviolet experiment) Task Team of the Marshall Space Flight Center (MSFC). This paper presents conceptual designs of the telescopes, provides descriptions of the telescope subsystem options selected for each concept, and outlines the potential evolution of their science capabilities.

Zeitlicher Verlauf der avaskulären Nekrose des Hüftkopfes bei Patienten mit Pemphigus vulgaris.

Science.gov (United States)

Balighi, Kamran; Daneshpazhooh, Maryam; Aghazadeh, Nessa; Saeidi, Vahide; Shahpouri, Farzam; Hejazi, Pardis; Chams-Davatchi, Cheyda

2016-10-01

Pemphigus vulgaris (PV) wird in der Regel mit systemischen Corticosteroiden und Immunsuppressiva behandelt. Avaskuläre Nekrose (AVN) des Hüftkopfes ist eine gut bekannte schwerere Komplikation einer Corticosteroid-Therapie. Die Charakteristika dieser schweren Komplikation bei PV sind nach wie vor unbekannt. Nicht kontrollierte, retrospektive Untersuchung aller PV-bedingten AVN-Fälle, die in einer iranischen Klinik für bullöse Autoimmunerkrankungen zwischen 1985 und 2013 diagnostiziert wurden. Anhand der Krankenakten von 2321 untersuchten PV-Patienten wurden 45 Fälle (1,93 %) von femoraler AVN identifiziert. Dreißig davon waren Männer. Das mittlere Alter bei der Diagnose der AVN betrug 47,4 ± 14,2 Jahre. Der mittlere Zeitraum zwischen der Diagnose des PV und dem Einsetzen der AVN lag bei 25,3 ± 18,3 Monaten. Mit Ausnahme von acht Fällen (17,8 %) setzte die AVN bei der Mehrheit der Patienten innerhalb von drei Jahren nach Diagnose des PV ein. Die mittlere kumulative Dosis von Prednisolon bei Patienten mit AVN betrug 13.115,8 ± 7041,1 mg. Zwischen der Prednisolon-Gesamtdosis und dem Zeitraum bis zum Einsetzen der AVN bestand eine starke Korrelation (p = 0,001). Bei Patienten mit Alendronateinnahme in der Vorgeschichte war dieser Zeitraum signifikant kürzer (p = 0,01). Die AVN ist eine schwere Komplikation einer Corticosteroid-Behandlung bei Patienten mit PV. Sie wird bei 2 % der Patienten beobachtet und tritt vor allem in den ersten drei Behandlungsjahren auf. Bei Patienten, die höhere Dosen von Prednisolon erhalten, setzt die AVN tendenziell früher ein. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

The Submillimeter Telescope (SMT) project

International Nuclear Information System (INIS)

Martin, R.N.; Baars, J.W.M.

1990-01-01

To exploit the potential of submillimeter astronomy, the Submillimeter Telescope (SMT) will be located at an altitude of 3178 meters on Emerald Peak 75 miles northeast of Tucson in Southern Arizona. The instrument is an altazimuth mounted f/13.8 Cassegrain homology telescope with two Nasmyth and bent Cassegrain foci. It will have diffraction limited performance at a wavelength of 300 microns and an operating overall figure accuracy of 15 microns rms. An important feature of the SMT is the construction of the primary and secondary reflectors out of aluminum-core CFRP face sheet sandwich panels, and the reflector backup structure and secondary support out of CFRP structural elements. This modern technology provides both a means for reaching the required precision of the SMT for both night and day operation (basically because of the low coefficient of thermal expansion and high strength-to-weight ratio of CFRP) and a potential route for the realization of lightweight telescopes of even greater accuracy in the future. The SMT will be the highest accuracy radio telescope ever built (at least a factor of 2 more accurate than existing telescopes). In addition, the SMT will be the first 10 m-class submillimeter telescope with a surface designed for efficient measurements at the important 350 microns wavelength atmospheric window. 9 refs

History of Robotic and Remotely Operated Telescopes

Science.gov (United States)

Genet, Russell M.

2011-03-01

While automated instrument sequencers were employed on solar eclipse expeditions in the late 1800s, it wasn't until the 1960s that Art Code and associates at Wisconsin used a PDP minicomputer to automate an 8-inch photometric telescope. Although this pioneering project experienced frequent equipment failures and was shut down after a couple of years, it paved the way for the first space telescopes. Reliable microcomputers initiated the modern era of robotic telescopes. Louis Boyd and I applied single board microcomputers with 64K of RAM and floppy disk drives to telescope automation at the Fairborn Observatory, achieving reliable, fully robotic operation in 1983 that has continued uninterrupted for 28 years. In 1985 the Smithsonian Institution provided us with a suburb operating location on Mt. Hopkins in southern Arizona, while the National Science Foundation funded additional telescopes. Remote access to our multiple robotic telescopes at the Fairborn Observatory began in the late 1980s. The Fairborn Observatory, with its 14 fully robotic telescopes and staff of two (one full and one part time) illustrates the potential for low operating and maintenance costs. As the information capacity of the Internet has expanded, observational modes beyond simple differential photometry opened up, bringing us to the current era of real-time remote access to remote observatories and global observatory networks. Although initially confined to smaller telescopes, robotic operation and remote access are spreading to larger telescopes as telescopes from afar becomes the normal mode of operation.

The Prince and the Hobby-Horse: Shakespeare and the Ambivalence of Early Modern Popular Culture

Directory of Open Access Journals (Sweden)

Natália Pikli

2013-03-01

Full Text Available The Shakespearean hobby-horse, mentioned emphatically in Hamlet, brings into focus a number of problems related to early modern popular culture. In the late sixteenth and early seventeenth centuries the word was characterised by semantic ambivalence, with simultaneously valid meanings of a breed of horse, a morris character, a foolish person, and a wanton woman. The overlapping of these meanings in different cultural discourses of the age (playtexts, emblem books, popular verse, pictures exemplifies the interaction of different productions of early modern popular culture, from social humiliating practices to festivals and public playhouses. This attests to a complex circulation of cultural memory regarding symbols of popular culture, paradoxically both ‘forgotten’ and ‘remembered’ as a basically oral-ritual culture was transformed into written forms. In this context, the Hamletian passage gains new overtones, while the different versions of the playtext (Q1 & 2: 1603, 1604, F: 1623 also offer insights into the changing attitudes regarding popular culture, as it became gradually commercialised and politicised in the following decades. Finally, Shakespeare’s The Winter’s Tale and Jonson’s Bartholomew Fair solidify a critical and sceptical attitude, which seems to have signalled the end of ‘Merry Old England’ on-stage and off-stage as well.

The Development of Replicated Optical Integral Field Spectrographs and their Application to the Study of Lyman-alpha Emission at Moderate Redshifts

Science.gov (United States)

Chonis, Taylor Steven

In the upcoming era of extremely large ground-based astronomical telescopes, the design of wide-field spectroscopic survey instrumentation has become increasingly complex due to the linear growth of instrument pupil size with telescope diameter for a constant spectral resolving power. The upcoming Visible Integral field Replicable Unit Spectrograph (VIRUS), a baseline array of 150 copies of a simple integral field spectrograph that will be fed by 3:36 x 104 optical fibers on the upgraded Hobby-Eberly Telescope (HET) at McDonald Observatory, represents one of the first uses of large-scale replication to break the relationship between instrument pupil size and telescope diameter. By dividing the telescope's field of view between a large number of smaller and more manageable instruments, the total information grasp of a traditional monolithic survey spectrograph can be achieved at a fraction of the cost and engineering complexity. To highlight the power of this method, VIRUS will execute the HET Dark Energy Experiment (HETDEX) and survey & 420 degrees2 of sky to an emission line flux limit of ˜ 10-17 erg s-1 cm -2 to detect ˜ 106 Lyman-alpha emitting galaxies (LAEs) as probes of large-scale structure at redshifts of 1:9 production of the suite of volume phase holographic (VPH) diffraction gratings for VIRUS is presented, which highlights the challenge and success associated with producing of a very large number of highly customized optical elements whose performance is crucial to meeting the efficiency requirements of the spectrograph system. To accommodate VIRUS, the HET is undergoing a substantial wide-field upgrade to increase its field of view to 22' in diameter. The previous HET facility Low Resolution Spectrograph (LRS), which was directly fed by the telescope's previous spherical aberration corrector, must be removed from the prime focus instrument package as a result of the telescope upgrades and instead be fiber-coupled to the telescope focal plane. For a

Magnetisches Tracking für die Navigation mit dem da Vinci® Surgical System

Science.gov (United States)

Nickel, Felix; Wegner, Ingmar; Kenngott, Hannes; Neuhaus, Jochen; Müller-Stich, Beat P.; Meinzer, Hans-Peter; Gutt, Carsten N.

In dieser Studie wurde untersucht ob in einem typischen OP-Aufbau mit dem da Vinci® Telemanipulator elektromagnetisches Tracking für die Realisation eines Navigationssystems eingesetzt werden kann. Hierfür wurde in einem realen OP-Aufbau untersucht, wie stark metallische und ferromagnetisch wirksame Objekte wie Operationstisch und Telemanipulator das elektromagnetische Feld des Trackingsystems beeinflussen. Die Ergebnisse zeigen, dass der Telemanipulator nur unwesentlich die Störung des Magnetfeldes durch den OP-Tisch verstärkt. Insbesondere die Bewegung der Instrumente im Trackingvolumen verursachte keine zusätzliche relevante Störung des Magnetfeldes. Bei Begrenzung des Trackingvolumens auf eine Länge von 190 mm, Höhe von 200mm und Breite von 400 mm war der maximale Fehler in diesem Bereich an allen Messpunkten kleiner 10 mm. Der Einsatz von elektromagnetischem Tracking für die Navigation mit dem da Vinci® Surgical System ist somit in einem begrenzten Arbeitsvolumen mit hinreichender Genauigkeit möglich.

Embryonic expression of zebrafish MiT family genes tfe3b, tfeb, and tfec.

Science.gov (United States)

Lister, James A; Lane, Brandon M; Nguyen, Anhthu; Lunney, Katherine

2011-11-01

The MiT family comprises four genes in mammals: Mitf, Tfe3, Tfeb, and Tfec, which encode transcription factors of the basic-helix-loop-helix/leucine zipper class. Mitf is well-known for its essential role in the development of melanocytes, however the functions of the other members of this family, and of interactions between them, are less well understood. We have now characterized the complete set of MiT genes from zebrafish, which totals six instead of four. The zebrafish genome contain two mitf (mitfa and mitfb), two tfe3 (tfe3a and tfe3b), and single tfeb and tfec genes; this distribution is shared with other teleosts. We present here the sequence and embryonic expression patterns for the zebrafish tfe3b, tfeb, and tfec genes, and identify a new isoform of tfe3a. These findings will assist in elucidating the roles of the MiT gene family over the course of vertebrate evolution. Copyright © 2011 Wiley-Liss, Inc.

Prospects for γ-ray imaging telescopes

International Nuclear Information System (INIS)

Carter, J.N.; Dean, A.J.; Ramsden, D.

1981-01-01

Apart from the requirement for a new, high angular-resolution gamma-ray telescope for the more precise location of known COS-B gamma-ray sources, there is also a need for another instrument that can be used in a search for the gamma-ray emission from specific X-ray-emitting objects. If there is to be any hope of relating gamma ray emission to specific candidate X-ray objects, then an angular resolution of typically a few minutes of arc is required to resolve adjacent sources in crowded regions of the sky such as the galactic centre. Efforts to improve the angular resolution of track-chamber telescopes are compared. For energies close to 1 MeV telescopes have either used collimators to restrict the field of view or have made use of the kinematics of the Compton scattering process to determine the direction of the incident photon. The use of coded aperture techniques in high angular resolution X-ray astronomy telescopes is reviewed. A practical telescope for astronomy at high energies described by Carter is mentioned. At low energies an imaging telescope could be constructed by making use of position-sensitive detectors initially developed for use in medical physics. Such a telescope is outlined in general terms and its benefits and uses given. (U.K.)

Gasification together with other residual materials; Vergasung gemeinsam mit anderen Reststoffen

Energy Technology Data Exchange (ETDEWEB)

Lungwitz, H. [Berliner Wasserbetriebe, Berlin (Germany)

1998-09-01

The commonest method of thermal sewage sludge treatment at present is still combustion in mono-fluidised-bed plants. The possibilities described in the introduction of this paper give an impression of the great variety of disposal methods with a thermal final stage among which one can choose today. The solution that has been found to the disposal problems of four sewage plants in Berlin shows by way of example how a Europe-wide tender can lead to an inexpensive, permanent, secure, and flexible disposal system which includes recycling and figures as part of an integrated disposal system for different wastes. This disposal system has found ready acceptance on account of its environmental friendliness and sparing consumption of resources. Unlike incineration plants, its construction did not meet with public resistance. [Deutsch] Die zur Zeit noch haeufigste thermische Klaerschlammbehandlung ist die Verbrennung in Mono-Wirbelschichtanlagen. Die einleitend geschilderten Moeglichkeiten lassen jedoch die Vielfalt erkennen, die jetzt bei der Wahl eines Entsorgungsweges mit thermischer Endstufe gegeben sind. Die Loesung der Entsorgungsprobleme fuer 4 Berliner Klaerwerke hat beispielhaft gezeigt wie z.B. mittels eines europaweiten Ausschreibungsverfahrens ein kostenguenstiger, zeitlich nicht begrenzter, sicherer und flexibler Entsorgungsweg mit stofflicher Verwertung im Rahmen eines Verbundkonzeptes mit anderen Abfallstoffen gefunden werden kann. Ein Verwertungsweg, der allgemein wegen seiner Umweltvertraeglichkeit und Ressourcenschonung grosse Akzeptanz erfahren hat. Widerstand, wie beim Bau von Verbrennungsanlagen, hat es nicht gegeben. (orig.)

Status of the MAGIC telescopes

Energy Technology Data Exchange (ETDEWEB)

Colin, Pierre; Carmona, Emiliano; Schweizer, Thomas; Sitarek, Julian [Max-Planck-Institut fuer Physik, Werner-Heisenberg Institut, Muenchen (Germany)

2010-07-01

MAGIC is a system of two 17-m Cherenkov telescopes located on La Palma (Canary islands),sensitive to gamma-rays above 30 GeV. It has been recently upgraded by a second telescope which strongly improves the sensitivity, particularly at low energy. Here we present the status of the MAGIC telescopes and an overview of the recent results obtained in single or stereoscopic mode. We also discuss the real performance of the new stereoscopic system based on Crab Nebula observations.

BULGELESS GIANT GALAXIES CHALLENGE OUR PICTURE OF GALAXY FORMATION BY HIERARCHICAL CLUSTERING ,

International Nuclear Information System (INIS)

Kormendy, John; Cornell, Mark E.; Drory, Niv; Bender, Ralf

2010-01-01

To better understand the prevalence of bulgeless galaxies in the nearby field, we dissect giant Sc-Scd galaxies with Hubble Space Telescope (HST) photometry and Hobby-Eberly Telescope (HET) spectroscopy. We use the HET High Resolution Spectrograph (resolution R ≡ λ/FWHM ≅ 15, 000) to measure stellar velocity dispersions in the nuclear star clusters and (pseudo)bulges of the pure-disk galaxies M 33, M 101, NGC 3338, NGC 3810, NGC 6503, and NGC 6946. The dispersions range from 20 ± 1 km s -1 in the nucleus of M 33 to 78 ± 2 km s -1 in the pseudobulge of NGC 3338. We use HST archive images to measure the brightness profiles of the nuclei and (pseudo)bulges in M 101, NGC 6503, and NGC 6946 and hence to estimate their masses. The results imply small mass-to-light ratios consistent with young stellar populations. These observations lead to two conclusions. (1) Upper limits on the masses of any supermassive black holes are M . ∼ 6 M sun in M 101 and M . ∼ 6 M sun in NGC 6503. (2) We show that the above galaxies contain only tiny pseudobulges that make up ∼ circ > 150 km s -1 , including M 101, NGC 6946, IC 342, and our Galaxy, show no evidence for a classical bulge. Four may contain small classical bulges that contribute 5%-12% of the light of the galaxy. Only four of the 19 giant galaxies are ellipticals or have classical bulges that contribute ∼1/3 of the galaxy light. We conclude that pure-disk galaxies are far from rare. It is hard to understand how bulgeless galaxies could form as the quiescent tail of a distribution of merger histories. Recognition of pseudobulges makes the biggest problem with cold dark matter galaxy formation more acute: How can hierarchical clustering make so many giant, pure-disk galaxies with no evidence for merger-built bulges? Finally, we emphasize that this problem is a strong function of environment: the Virgo cluster is not a puzzle, because more than 2/3 of its stellar mass is in merger remnants.

Performance of the Multi-Spectral Solar Telescope Array. III - Optical characteristics of the Ritchey-Chretien and Cassegrain telescopes

Science.gov (United States)

Hoover, Richard B.; Baker, Phillip C.; Hadaway, James B.; Johnson, R. B.; Peterson, Cynthia; Gabardi, David R.; Walker, Arthur B., Jr.; Lindblom, J. F.; Deforest, Craig; O'Neal, R. H.

1991-12-01

The Multi-Spectral Solar Telescope Array (MSSTA), which is a sounding-rocket-borne observatory for investigating the sun in the soft X-ray/EUV and FUV regimes of the electromagnetic spectrum, utilizes single reflection multilayer coated Herschelian telescopes for wavelengths below 100 A, and five doubly reflecting multilayer coated Ritchey-Chretien and two Cassegrain telescopes for selected wavelengths in the EUV region between 100 and 1000 A. The paper discusses the interferometric alignment, testing, focusing, visible light testing, and optical performance characteristics of the Ritchey-Chretien and Cassegrain telescopes of MSSTA. A schematic diagram of the MSSTA Ritchey-Chretien telescope is presented together with diagrams of the system autocollimation testing.

MIT Mints a Valuable New Form of Academic Currency

Science.gov (United States)

Carey, Kevin

2012-01-01

The Massachusetts Institute of Technology (MIT) has invented or improved many world-changing things--radar, information theory, and synthetic self-replicating molecules, to name a few. Last month the university announced, to mild fanfare, an invention that could be similarly transformative, this time for higher education itself. It is called MITx.…

Telescopes and Techniques

CERN Document Server

Kitchin, C R

2013-01-01

Telescopes and Techniques has proved itself in its first two editions, having become probably one of the most widely used astronomy texts, both for amateur astronomers and astronomy and astrophysics undergraduates. Both earlier editions of the book were widely used for introductory practical astronomy courses in many universities. In this Third Edition the author guides the reader through the mathematics, physics and practical techniques needed to use today's telescopes (from the smaller models to the larger instruments installed in many colleges) and how to find objects in the sky. Most of the physics and engineering involved is described fully and requires little prior knowledge or experience. Both visual and electronic imaging techniques are covered, together with an introduction to how data (measurements) should be processed and analyzed. A simple introduction to radio telescopes is also included. Brief coverage of the more advanced topics of photometry and spectroscopy are included, but mainly to enable ...

Educational Outreach at the M.I.T. Plasma Fusion Center

Science.gov (United States)

Censabella, V.

1996-11-01

Educational outreach at the MIT Plasma Fusion Center consists of volunteers working together to increase the public's knowledge of fusion and plasma-related experiments. Seeking to generate excitement about science, engineering and mathematics, the PFC holds a number of outreach activities throughout the year, such as Middle and High School Outreach Days. Outreach also includes the Mr. Magnet Program, which uses an interactive strategy to engage elementary school children. Included in this year's presentation will be a new and improved C-MOD Jr, a confinement video game which helps students to discover how computers manipulate magnetic pulses to keep a plasma confined for as long as possible. Also on display will be an educational toy created by the Cambridge Physics Outlet, a PFC spin-off company. The PFC maintains a Home Page on the World Wide Web, which can be reached at http://cmod2.pfc.mit.edu/.

Properties of hybrid stars in an extended MIT bag model

International Nuclear Information System (INIS)

Bao Tmurbagan; Liu Guangzhou; Zhu Mingfeng

2009-01-01

The properties of hybrid stars are investigated in the framework of the relativistic mean field theory (RMFT) and an MIT bag model with density-dependent bag constant to describe the hadron phase (HP) and quark phase (QP), respectively. We find that the density-dependent B(ρ) decreases with baryon density ρ; this decrement makes the strange quark matter become more energetically favorable than ever; which makes the threshold densities of the hadron-quark phase transition lower than those of the original bag constant case. In this case, the hyperon degrees of freedom can not be considered. As a result, the equations of state of a star in the mixed phase (MP) become softer whereas those in the QP become stiffer, and the radii of the star obviously decrease. This indicates that the extended MIT bag model is more suitable to describe hybrid stars with small radii. (authors)

VizieR Online Data Catalog: Solar neighborhood. XXXVII. RVs for M dwarfs (Benedict+, 2016)

Science.gov (United States)

Benedict, G. F.; Henry, T. J.; Franz, O. G.; McArthur, B. E.; Wasserman, L. H.; Jao, W.-C.; Cargile, P. A.; Dieterich, S. B.; Bradley, A. J.; Nelan, E. P.; Whipple, A. L.

2017-05-01

, National optical astronomy observatory (WIYN) 3.5m (Horch et al. 2012, Cat. J/AJ/143/10). Where available, we use astrometric observations from HST instruments other than the FGSs, including the Faint Object Camera (FOC; Barbieri et al. 1996A&A...315..418B), the Faint Object Spectrograph (FOS; Schultz et al. 1998PASP..110...31S), the Near-Infrared Camera and Multi-Object Spectrometer (NICMOS; Golimowski et al. 2004AJ....128.1733G), and the Wide-Field Planetary Camera 2 (WFPC2; Schroeder et al. 2000AJ....119..906S; Dieterich et al. 2012, Cat. J/AJ/144/64). Our radial velocity measurements, listed in table3, are from two sources. We obtained most radial velocity data with the McDonald 2.1m Struve telescope and the Sandiford Cassegrain Echelle spectrograph, hereafter CE. The CE delivers a dispersion equivalent to 2.5km/s/pix (R=λ/Δλ=60000) with a wavelength range of 5500{<=}λ{<=}6700Å spread across 26 orders (apertures). The McDonald data were collected during 33 observing runs from 1995 to 2009. Some GJ 623 AB velocities came from the Hobby-Eberly Telescope (HET) using the Tull Spectrograph. (3 data files).

The South Pole Telescope

Energy Technology Data Exchange (ETDEWEB)

Ruhl, J.E.; Ade, P.A.R.; Carlstrom, J.E.; Cho, H.M.; Crawford,T.; Dobbs, M.; Greer, C.H.; Halverson, N.W.; Holzapfel, W.L.; Lanting,T.M.; Lee, A.T.; Leitch, E.M.; Leong, J.; Lu, W.; Lueker, M.; Mehl, J.; Meyer, S.S.; Mohr, J.J.; Padin, S.; Plagge, T.; Pryke, C.; Runyan, M.C.; Schwan, D.; Sharp, M.K.; Spieler, H.; Staniszewski, Z.; Stark, A.A.

2004-11-04

A new 10 meter diameter telescope is being constructed for deployment at the NSF South Pole research station. The telescope is designed for conducting large-area millimeter and sub-millimeter wave surveys of faint, low contrast emission, as required to map primary and secondary anisotropies in the cosmic microwave background. To achieve the required sensitivity and resolution, the telescope design employs an off-axis primary with a 10 m diameter clear aperture. The full aperture and the associated optics will have a combined surface accuracy of better than 20 microns rms to allow precision operation in the submillimeter atmospheric windows. The telescope will be surrounded with a large reflecting ground screen to reduce sensitivity to thermal emission from the ground and local interference. The optics of the telescope will support a square degree field of view at 2mm wavelength and will feed a new 1000-element micro-lithographed planar bolometric array with superconducting transition-edge sensors and frequency-multiplexed readouts. The first key project will be to conduct a survey over 4000 degrees for galaxy clusters using the Sunyaev-Zeldovich Effect. This survey should find many thousands of clusters with a mass selection criteria that is remarkably uniform with redshift. Armed with redshifts obtained from optical and infrared follow-up observations, it is expected that the survey will enable significant constraints to be placed on the equation of state of the dark energy.

Umgang mit Antithrombotika bei Operationen an der Haut vor und nach Publikation der entsprechenden S3-Leitlinie.

Science.gov (United States)

Gaskins, Matthew; Dittmann, Martin; Eisert, Lisa; Werner, Ricardo Niklas; Dressler, Corinna; Löser, Christoph; Nast, Alexander

2018-03-01

Laut einer Befragung im Jahre 2012 war der Umgang mit Antithrombotika bei dermatochirurgischen Eingriffen in Deutschland sehr heterogen. 2014 wurde erstmals eine evidenzbasierte Leitlinie zu diesem Thema veröffentlicht. Es wurde eine anonyme Befragung derselben Stichprobe zum Umgang mit Antithrombotika sowie zu Kenntnissen der Leitlinie durchgeführt. Die Ergebnisse wurden als relative Häufigkeiten berichtet und denen aus 2012 gegenübergestellt. 208 Antwortbögen wurden ausgewertet (Rücklaufquote: 36,6 %). Die große Mehrheit der Dermatologen erklärte, kleinere Eingriffe unter Fortführung der Therapie mit Phenprocoumon, niedrig dosierter Acetylsalicylsäure (≤ 100 mg) und Clopidogrel sowie mit direkten oralen Antikoagulanzien durchzuführen. Bei größeren Eingriffen war der Umgang hingegen weiterhin heterogen, insbesondere unter niedergelassenen Dermatologen. Der Anteil der Dermatologen, die Phenprocoumon, Acetylsalicylsäure und Clopidogrel leitlinienkonform verwendeten, hat sich insgesamt vergrößert. Führten 2012 beispielsweise 53,8 % der Klinikärzte bzw. 36,3 % der niedergelassenen Dermatologen eine große Exzision unter Fortführung der Therapie mit niedrig dosierter Acetylsalicylsäure durch, taten dies 2017 90,2 % bzw. 57,8 % (Phenprocoumon: 33,8 % bzw. 11,9 % auf 63,9 % bzw. 29,9 %; Clopidogrel: 36,9 % bzw. 23,2 % auf 63,9 % bzw. 30,6 %). Unter den Klinikärzten war ein hoher Anteil mit der Leitlinie vertraut und fand diese hilfreich. Eine Zunahme des leitlinienkonformen Verhaltens war bei allen Eingriffen zu verzeichnen. Bei größeren Eingriffen zeigte sich trotz deutlicher Verbesserung die Notwendigkeit verstärkter Anstrengungen zur Leitlinienumsetzung bzw. zur Identifizierung von Implementierungsbarrieren. © 2018 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

Commissioning and first tests of the MAGIC telescope

Science.gov (United States)

Baixeras, C.; Bastieri, D.; Bigongiari, C.; Blanch, O.; Blanchot, G.; Bock, R.; Bretz, T.; Chilingarian, A.; Coarasa, J. A.; Colombo, E.; Contreras, J. C.; Corti, D.; Cortina, J.; Domingo, C.; Domingo, E.; Ferenc, D.; Fernández, E.; Flix, J.; Fonseca, V.; Font, L.; Galante, N.; Gaug, M.; Garczarczyk, M.; Gebauer, J.; Giller, M.; Goebel, F.; Hengstebeck, T.; Jacone, P.; de Jager, O. C.; Kalekin, O.; Kestel, M.; Kneiske, T.; Laille, A.; López, M.; López, J.; Lorenz, E.; Mannheim, K.; Mariotti, M.; Martínez, M.; Mase, K.; Merck, M.; Meucci, M.; Miralles, L.; Mirzoyan, R.; Moralejo, A.; Wilhelmi, E. Oña; Orduña, R.; Paneque, D.; Paoletti, R.; Pascoli, D.; Pavel, N.; Pegna, R.; Peruzzo, L.; Piccioli, A.; Roberts, A.; Reyes, R.; Saggion, A.; Sánchez, A.; Sartori, P.; Scalzotto, V.; Schweizer, T.; Sillanpaa, A.; Sobczynska, D.; Stamerra, A.; Stepanian, A.; Stiehler, R.; Takalo, L.; Teshima, M.; Tonello, N.; Torres, A.; Turini, N.; Vitale, V.; Volkov, S.; Wagner, R. M.; Wibig, T.; Wittek, W.

2004-02-01

Major Atmospheric Gamma Imaging Cherenkov telescope is starting its operations with a set of engineering runs to tune the telescope subsystem elements to be ready for the first physics campaign. Many technical improvements have been developed and implemented in several elements of the telescope to reach the lowest energy threshold ever obtained by an Imaging Atmospheric Cherenkov Telescope. A general description of the telescope is presented. The commissioning of the telescope's elements is described and the expected performances are reviewed with the final detector set-up.

Center for Multiscale Plasma Dynamics: Report on Activities (UCLA/MIT), 2009-2010

Energy Technology Data Exchange (ETDEWEB)

Carter, Troy Alan [Univ. of California, Los Angeles, CA (United States)

2014-10-03

The final “phaseout” year of the CMPD ended July 2010; a no cost extension was requested until May 2011 in order to enable the MIT subcontract funds to be fully utilized. Research progress over this time included verification and validation activities for the BOUT and BOUT++ code, studies of spontaneous reconnection in the VTF facility at MIT, and studies of the interaction between Alfv´en waves and drift waves in LAPD. The CMPD also hosted the 6th plasma physics winter school in 2010 (jointly with the NSF frontier center the Center for Magnetic Self-Organization, significant funding came from NSF for this most recent iteration of theWinter School).

European Extremely Large Telescope: progress report

Science.gov (United States)

Tamai, R.; Spyromilio, J.

2014-07-01

The European Extremely Large Telescope is a project of the European Southern Observatory to build and operate a 40-m class optical near-infrared telescope. The telescope design effort is largely concluded and construction contracts are being placed with industry and academic/research institutes for the various components. The siting of the telescope in Northern Chile close to the Paranal site allows for an integrated operation of the facility providing significant economies. The progress of the project in various areas is presented in this paper and references to other papers at this SPIE meeting are made.

Preliminary Cost Model for Space Telescopes

Science.gov (United States)

Stahl, H. Philip; Prince, F. Andrew; Smart, Christian; Stephens, Kyle; Henrichs, Todd

2009-01-01

Parametric cost models are routinely used to plan missions, compare concepts and justify technology investments. However, great care is required. Some space telescope cost models, such as those based only on mass, lack sufficient detail to support such analysis and may lead to inaccurate conclusions. Similarly, using ground based telescope models which include the dome cost will also lead to inaccurate conclusions. This paper reviews current and historical models. Then, based on data from 22 different NASA space telescopes, this paper tests those models and presents preliminary analysis of single and multi-variable space telescope cost models.

Merz telescopes a global heritage worth preserving

CERN Document Server

2017-01-01

This book comprises a fascinating collection of contributions on the Merz telescopes in Italy that collectively offer the first survey on historical large refracting telescopes in the country, drawing on original documents and photographs. It opens with a general introduction on the importance of Merz telescopes in the history of astronomy and analyses of the local and international contexts in which the telescopes were made. After examination of an example of the interaction between the maker and the astronomer in the construction and maintenance of these refractors, the history of the Merz telescopes at the main Italian observatories in the nineteenth century is described in detail. Expert testimony is also provided on how these telescopes were successfully used until the second half of the twentieth century for research purposes, thus proving their excellent optical qualities.

Status of the MIT-Bates South Hall Ring commissioning

International Nuclear Information System (INIS)

Flanz, J.B.; Jacobs, K.D.; McAllister, B.; Averill, R.; Bradley, S.; Carter, A.; Dow, K.; Farkondeh, M.; Ihloff, E.; Kowalski, S.

1993-01-01

The MIT-Bates South Hall Ring construction project is now nearly complete. At this time the Energy Compression System, the SHR Injection Line and the South Hall Ring itself are complete. The SHR Extraction Line is complete but has not been connected to the ring. Commissioning with beam of the completed beam lines has been started. The MIT-Bates South Hall Ring (SHR) is an electron storage ring used with the 1 GeV Bates electron accelerator to increase the effective duty factor and luminosity. A beam can be stored for use with an internal target, thus allowing for high duty factor, high luminosity experiments. External beams with high duty factor can be obtained using resonant extraction. The new systems associated with the SHR include the Energy Compression System (ECS), the Injection line, and the Extraction line. The authors have commissioned the ECS, the new injection line and the SHR without RF. This includes transporting beam, measuring beam phase space parameters using critical injection elements including a high voltage electrostatic septum, a fast beam kicker, and storing a beam in the SHR

Furosemide urogram in patients with neobladder; Das Diureseurogramm bei Patienten mit Harnblasenersatz

Energy Technology Data Exchange (ETDEWEB)

Merkle, E.M. [Univ. Ulm (Germany). Abt. Radiologie; Aschoff, A.J. [Univ. Ulm (Germany). Abt. Radiologie; Bachor, R. [Univ. Ulm (Germany). Abt. fuer Urologie; Vogel, J. [Univ. Ulm (Germany). Abt. Radiologie; Merk, J. [Univ. Ulm (Germany). Abt. Radiologie; Brambs, H.J. [Univ. Ulm (Germany). Abt. Radiologie

1996-11-01

Purpose: To differentiate between urodynamically relevant obstruction and functionally unimportant dilation of the upper urinary tract in patients with neobladder using a modified furosemide urogram. Method: An excretory urogram with furosemide loading was carried out in 19 patients with neobladder and sonographically and urographically confirmed dilation of the upper urinary tract. Once strong contrasting of the renal pelves and calyces has been achieved, 20 mg of furosemide were applied and late radiographs were obtained at 15 min and 30 min, respectively. An obstruction was defined as increasing dilation of the renal pelves and calices during forced diuresis and lack of washout effect of the contrast medium. Results: In 32 cases, the renoureteral unit (RUU) was dilated on ultrasound. Of these, 25 RUU`s showed good emptyness of contrast medium upon stimulation of diuresis, six RUU`s returned a borderline findings, while one RUU was found to exhibit a decompensated anastomotic stenosis, which was dilated. Two further patients with bordeline findings were later treated surgically due to their pain symptoms. No patient required further preoperative diagnostic procedures. Conclusions: The modified furosemide urogram represents a cost-effective diagnostic orientation strategy in patients with neobladder and dilated renal pelves and calyses and is both well-tolerated by patients and meets with broad acceptance from the urologic staff. (orig.) [Deutsch] Ziel: Differenzierung zwischen urodynamisch relevanter Obstruktion und funktionell bedeutungsloser Dilatation des oberen Harntraktes bei Patienten mit Harnblasenersatz durch ein modifiziertes Diureseurogramm. Methodik: Bei 19 Patienten mit Harnableitung und sonographisch sowie urographisch nachgewiesener Erweiterung des oberen Harntraktes wurde ein Ausscheidungsurogramm mit Furosemidbelastung durchgefuehrt. Bei kraeftiger Kontrastierung des erweiterten Nierenbeckenkelchsystems (NBKS) wurden 20 mg Furosemid appliziert und

ASTERIA: Arcsecond Space Telescope Enabling Research in Astrophysics

Science.gov (United States)

Knapp, M.; Seager, S.; Smith, M. W.; Pong, C. M.

2017-12-01

ASTERIA (Arcsecond Space Telescope Enabling Research in Astrophysics) is a technology demonstration and opportunistic science mission to advance the state of the art in CubeSat capabilities for astrophysical measurements. The goal of ASTERIA is to achieve arcsecond-level line of sight pointing error and highly stable focal plane temperature control. These technologies will enable precision photometry, i.e. the careful measurement of stellar brightness over time. This in turn provides a way to study stellar activity, transiting exoplanets, and other astrophysical phenomena, both during the ASTERIA mission and in future CubeSat constellations. ASTERIA is a 6U CubeSat (roughly 10 x 20 x 30 cm, 12 kg) that will operate in low-Earth orbit. The payload consists of a lens and baffle assembly, a CMOS imager, and a two-axis piezoelectric positioning stage on which the focal plane is mounted. A set of commercial reaction wheels provides coarse attitude control. Fine pointing control is achieved by tracking a set of guide stars on the CMOS sensor and moving the piezoelectric stage to compensate for residual pointing errors. Precision thermal control is achieved by isolating the payload from the spacecraft bus, passively cooling the detector, and using trim heaters to perform small temperature corrections over the course of an observation. The ASTERIA project is a collaboration with MIT and is funded at JPL through the Phaeton Program for training early career employees. Flight hardware was delivered in June 2017, with launch expected in August 2017 and deployment targeted for October 2017.

Clinical accuracy of inflationary oscillometry in pregnancy and pre-eclampsia: Omron-MIT Elite.

Science.gov (United States)

Chung, Y; Brochut, M C; de Greeff, A; Shennan, A H

2012-10-01

To evaluate the accuracy of the Omron MIT Elite in pregnancy and pre-eclampsia according to the British Hypertension Society protocol (BHS). Prospective observational study. Antenatal clinics and wards at St. Thomas' Hospital (London, UK). Forty-five pregnant women including 15 with pre-eclampsia. Nine sequential same arm blood pressure (BP) measurements were taken from each woman by trained observers, alternating between mercury sphygmomanometry and the test device. Grading criteria of the BHS protocol (A/B grade=pass; C/D=fail). The Omron MIT Elite achieved a grade A/A in both pregnancy and pre-eclampsia. The mean difference (SD) between the mercury standard and the device in pregnancy was -1.1 (5.2)mmHg and 1.5 (4.8)mmHg for systolic and diastolic BP respectively compared to 0.2 (5.3)mmHg and 2.2 (5.5)mmHg in pre-eclampsia. The Omron MIT Elite can be recommended for use in pregnancy and pre-eclampsia according to the BHS protocol. To date, this is the most accurate automated BP device validated in pre-eclampsia. Copyright © 2012. Published by Elsevier B.V.

UBER DIE SCHREIBUNG UND RECHTSCHREIBUNG MIT BESONDERER RÜCKSICHT AUF DIE RECHTSCHREIBUNGSLÖSUNGEN IN "FLUMINENSIA" VON FRAN KURELAC

Directory of Open Access Journals (Sweden)

Lada Badurina

1990-01-01

Full Text Available Im Artikel sind zunächst Grundsetzen der Schreibung und der Rechtschreibung dargestellt, demnach die Schreibung und die Rechtschreibung in "Fluminensia" von Fran Kurelac. Die von Kurelac vorgeschlagenen Lösungen sind mit den Lösungen seiner unmittelbaren Vorgänger und Zeitgenossen vergleicht, sowie mit der heutigen Rechtschreibungspraxis. Für die von Kurelac vorgeschlagne Schreibung ist festgestellt, daß es sich um ein beständiges System handelt, das von der Tradition ausgeht und das sich nur in eingen Lösungen von heutigen unterscheidet. In der Rechtschreibung überwiegt der morphologische Grundsatz, was leicht in Verbindung mit den Grundgedanken der Philologischen Schule in Rijeka zu steilen ist.

Distinct Mechanisms of Recognizing Endosomal Sorting Complex Required for Transport III (ESCRT-III) Protein IST1 by Different Microtubule Interacting and Trafficking (MIT) Domains*

Science.gov (United States)

Guo, Emily Z.; Xu, Zhaohui

2015-01-01

The endosomal sorting complex required for transport (ESCRT) machinery is responsible for membrane remodeling in a number of biological processes including multivesicular body biogenesis, cytokinesis, and enveloped virus budding. In mammalian cells, efficient abscission during cytokinesis requires proper function of the ESCRT-III protein IST1, which binds to the microtubule interacting and trafficking (MIT) domains of VPS4, LIP5, and Spartin via its C-terminal MIT-interacting motif (MIM). Here, we studied the molecular interactions between IST1 and the three MIT domain-containing proteins to understand the structural basis that governs pairwise MIT-MIM interaction. Crystal structures of the three molecular complexes revealed that IST1 binds to the MIT domains of VPS4, LIP5, and Spartin using two different mechanisms (MIM1 mode versus MIM3 mode). Structural comparison revealed that structural features in both MIT and MIM contribute to determine the specific binding mechanism. Within the IST1 MIM sequence, two phenylalanine residues were shown to be important in discriminating MIM1 versus MIM3 binding. These observations enabled us to deduce a preliminary binding code, which we applied to provide CHMP2A, a protein that normally only binds the MIT domain in the MIM1 mode, the additional ability to bind the MIT domain of Spartin in the MIM3 mode. PMID:25657007

Distinct mechanisms of recognizing endosomal sorting complex required for transport III (ESCRT-III) protein IST1 by different microtubule interacting and trafficking (MIT) domains.

Science.gov (United States)

Guo, Emily Z; Xu, Zhaohui

2015-03-27

The endosomal sorting complex required for transport (ESCRT) machinery is responsible for membrane remodeling in a number of biological processes including multivesicular body biogenesis, cytokinesis, and enveloped virus budding. In mammalian cells, efficient abscission during cytokinesis requires proper function of the ESCRT-III protein IST1, which binds to the microtubule interacting and trafficking (MIT) domains of VPS4, LIP5, and Spartin via its C-terminal MIT-interacting motif (MIM). Here, we studied the molecular interactions between IST1 and the three MIT domain-containing proteins to understand the structural basis that governs pairwise MIT-MIM interaction. Crystal structures of the three molecular complexes revealed that IST1 binds to the MIT domains of VPS4, LIP5, and Spartin using two different mechanisms (MIM1 mode versus MIM3 mode). Structural comparison revealed that structural features in both MIT and MIM contribute to determine the specific binding mechanism. Within the IST1 MIM sequence, two phenylalanine residues were shown to be important in discriminating MIM1 versus MIM3 binding. These observations enabled us to deduce a preliminary binding code, which we applied to provide CHMP2A, a protein that normally only binds the MIT domain in the MIM1 mode, the additional ability to bind the MIT domain of Spartin in the MIM3 mode. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

Open principle for large high-resolution solar telescopes

NARCIS (Netherlands)

Hammerschlag, R.H.; Bettonvil, F.C.M.; Jägers, A.P.L.; Sliepen, G.

2009-01-01

Vacuum solar telescopes solve the problem of image deterioration inside the telescope due to refractive index fluctuations of the air heated by the solar light. However, such telescopes have a practical diameter limit somewhat over 1 m. The Dutch Open Telescope (DOT) was the pioneering demonstrator

The My Meal Intake Tool (M-MIT): Validity of a Patient Self- Assessment for Food and Fluid Intake at a Single Meal.

Science.gov (United States)

McCullough, J; Keller, H

2018-01-01

Hospital malnutrition is an under-recognized issue that leads to a variety of adverse outcomes, especially for older adults. Food/fluid intake (FFI) monitoring in hospital can be used to identify those who are improving and those who need further treatment. Current monitoring practices such as calorie counts are impractical for all patients and a patient-completed tool, if valid, could support routine FFI monitoring. The aim of this research was to determine whether the patient-completed My Meal Intake Tool (M-MIT) can accurately represent FFI at a single meal. Cross-sectional, multi-site. Four acute care hospitals in Canada. 120 patients (65+ yrs, adequate cognition). Participants completed M-MIT for a single meal. Food and fluid waste was visually estimated by a research dietitian at each hospital. Sensitivity (Se), specificity (Sp) and overall agreement were calculated for both food and fluid intake by comparing M-MIT and dietitian estimations to determine criterion validity of M-MIT. Patient and research dietitian comments were used to make revisions to the M-MIT. Using a cut-point of ≤50% intake, Se was 76.2% and 61.9% and Sp was 74.0% and 80.5% for solid and fluids respectively (pMIT identified a greater proportion of participants (37.2%) as having low FFI (≤50%) than dietitians (25.0%), as well as a greater proportion identified with low fluid intake (28.3% vs. 24.6%). Modest revisions were made to improve the tool. This study has demonstrated initial validity of M-MIT for use in older patients with adequate cognition. Use of M-MIT could promote FFI monitoring as a routine practice to make clinical decisions about care.

Analysis of polarization introduced due to the telescope optics of the Thirty Meter Telescope

Science.gov (United States)

Anche, Ramya Manjunath; Sen, Asoke Kumar; Anupama, Gadiyara Chakrapani; Sankarasubramanian, Kasiviswanathan; Skidmore, Warren

2018-01-01

An analytical model has been developed to estimate the polarization effects, such as instrumental polarization (IP), crosstalk (CT), and depolarization, due to the optics of the Thirty Meter Telescope. These are estimated for the unvignetted field-of-view and the wavelengths of interest. The model estimates an IP of 1.26% and a CT of 44% at the Nasmyth focus of the telescope at the wavelength of 0.6 μm at field angle zero with the telescope pointing to zenith. Mueller matrices have been estimated for the primary, secondary, and Nasmyth mirrors. It is found that some of the Mueller matrix elements of the primary and secondary mirrors show a fourfold azimuthal antisymmetry, which indicates that the polarization at the Cassegrain focus is negligible. At the inclined Nasmyth mirror, there is no azimuthal antisymmetry in the matrix elements, and this results in nonzero values for IP and CT, which would negatively impact the polarization measurements at the telescope focus. The averaged Mueller matrix is estimated at the Nasmyth focus at different instrument ports and various zenith angles of the telescope. The variation in the Mueller matrix elements for different coatings is also estimated. The impact of this polarization effect on the science case requirements has been discussed. This analysis will help in achieving precise requirements for future instruments with polarimetric capability.

”Mitä tänään on tarjolla?” : opiskelijaruokailu laadusta mielikuviin

OpenAIRE

Partanen, Elina

2008-01-01

Työn tavoitteena oli selvittää, mitä opiskelijat yleensä syövät lounaalla opiskelijaravintolassa ja mitä mieltä he olivat tarjotusta lounasruuasta. Jyväskylän ammattikorkeakoululla on viisi eri ruokapalveluiden tarjoajaa, ja jokaisella on hieman toisistaan poikkeava liikekonsepti. Tutkimus toteutettiin sähköpostikyselynä Digium-ohjelman avulla ammattikorkeakoulun eri alojen opiskelijoille. Kyselyyn oli mahdollista vastata 8.4.2008 – 22.4.2008 välisenä aikana. Kyselyyn vastasi 341. Kyselyn tul...

Epstein-Barr Virus-Encoded RNAs: Key Molecules in Viral Pathogenesis

Energy Technology Data Exchange (ETDEWEB)

Iwakiri, Dai [Institute for Genetic Medicine, Hokkaido University, N15 W7 Kita-Ku, Sapporo 060-0815 (Japan)

2014-08-06

The Epstein-Barr virus (EBV) is known as an oncogenic herpesvirus that has been implicated in the pathogenesis of various malignancies. EBV-encoded RNAs (EBERs) are non-coding RNAs expressed abundantly in latently EBV-infected cells. Herein, I summarize the current understanding of the functions of EBERs, including the interactions with cellular factors through which EBERs contribute to EBV-mediated pathogenesis. Previous studies have demonstrated that EBERs are responsible for malignant phenotypes in lymphoid cells, and can induce several cytokines that can promote the growth of various EBV-infected cancer cells. EBERs were also found to bind retinoic acid-inducible gene I (RIG-I) and thus activate its downstream signaling. Furthermore, EBERs induce interleukin-10, an autocrine growth factor for Burkitt’s lymphoma cells, by activating RIG-I/interferon regulatory factor 3 pathway, suggesting that EBER-mediated innate immune signaling modulation contributes to EBV-mediated oncogenesis. Recently, EBV-infected cells were reported to secret EBERs, which were then recognized by toll-like receptor 3 (TLR3), leading to the induction of type I interferon and inflammatory cytokines, and subsequent immune activation. Furthermore, EBER1 was detected in the sera of patients with active EBV-infectious diseases, suggesting that EBER1-meidated TLR3 signaling activation could account for the pathogenesis of active EBV-infectious diseases.

Epstein-Barr Virus-Encoded RNAs: Key Molecules in Viral Pathogenesis

International Nuclear Information System (INIS)

Iwakiri, Dai

2014-01-01

The Epstein-Barr virus (EBV) is known as an oncogenic herpesvirus that has been implicated in the pathogenesis of various malignancies. EBV-encoded RNAs (EBERs) are non-coding RNAs expressed abundantly in latently EBV-infected cells. Herein, I summarize the current understanding of the functions of EBERs, including the interactions with cellular factors through which EBERs contribute to EBV-mediated pathogenesis. Previous studies have demonstrated that EBERs are responsible for malignant phenotypes in lymphoid cells, and can induce several cytokines that can promote the growth of various EBV-infected cancer cells. EBERs were also found to bind retinoic acid-inducible gene I (RIG-I) and thus activate its downstream signaling. Furthermore, EBERs induce interleukin-10, an autocrine growth factor for Burkitt’s lymphoma cells, by activating RIG-I/interferon regulatory factor 3 pathway, suggesting that EBER-mediated innate immune signaling modulation contributes to EBV-mediated oncogenesis. Recently, EBV-infected cells were reported to secret EBERs, which were then recognized by toll-like receptor 3 (TLR3), leading to the induction of type I interferon and inflammatory cytokines, and subsequent immune activation. Furthermore, EBER1 was detected in the sera of patients with active EBV-infectious diseases, suggesting that EBER1-meidated TLR3 signaling activation could account for the pathogenesis of active EBV-infectious diseases

Optical Design of the STAR-X Telescope

Science.gov (United States)

Saha, Timo T.; Zhang, William W.; McClelland, Ryan S.

2017-01-01

Top-level science goals of the Survey and Time-domain Astrophysical Research eXplorer (STAR-X) include: investigations of most violent explosions in the universe, study of growth of black holes across cosmic time and mass scale, and measure how structure formation heats majority of baryons in the universe. To meet these goals, the field-of-view of the telescope should be about 1 square-degree, the angular resolution should be 5 arc-seconds or below across large part of the field-of-view. The on-axis effective area at 1 KeV should be about 2,000 sq cm. Payload cost and launch considerations limit the outer diameter, focal length, and mass to 1.3 meters, 5 meters, and 250 kilograms, respectively. Telescope design is based on a segmented meta-shell approach we have developed at Goddard Space Flight Center for the STAR-X telescope. The telescope shells are divided into 30-degree segments. Individual telescopes and meta-shells are nested inside each other to meet the effective area requirements in 0.5 - 6.0 KeV range. We consider Wolter-Schwarzschild, and Modified-Wolter-Schwarzschild telescope designs as basic building blocks of the nested STAR-X telescope. These designs offer an excellent resolution over a large field of views. Nested telescopes are vulnerable to stray light problems. We have designed a multi-component baffle system to eliminate direct and single-reflection light paths inside the telescopes. Large number of internal and external baffle vane structures are required to prevent stray rays from reaching the focal plane. We have developed a simple ray-trace based tool to determine the dimensions and locations of the baffles. In this paper, we present the results of our trade studies, baffle design studies, and optical performance analyses of the STAR-X telescope.

Problembasiertes kollaboratives Lernen mit virtuellen Patienten in der Kinderheilkunde: ein Beispiel aus der Ausbildungspraxis

Directory of Open Access Journals (Sweden)

Sostmann, Kai

2009-02-01

Full Text Available Der studentische Unterricht in der Kinderheilkunde an der Charité hat seit 1999 mehrere Umstrukturierungen durchlaufen. Mit der Einführung der neuen ärztlichen Approbationsordnung 2004 im Regelstudiengang (RSG und dem Modellcurriculum Reformstudiengang Medizin (RSM 1999 müssen zwei Curricula parallel neu konzipiert und gepflegt werden. Durch den Schwerpunkt Unterricht am Krankenbett (UaK im RSG ergaben sich neue didaktische, pädagogische und infrastrukturelle Anforderungen. Die technische und inhaltliche Weiterentwicklung der Einsatzmöglichkeiten elektronischer Lernszenarien durch e-Learning im Rahmen des BMBF-geförderten Projektes ELWIS-MED, ermöglichte die Erprobung der curricularen Implementierung von e-Learning-Modulen im Pflichtunterricht. Der UaK wurde durch die Bearbeitung kinderheilkundlicher elektronischer Lernfälle online ergänzt. Die Studierenden sollten tutoriell betreute Diskussionen zu fachlichen Aufgabenstellungen online führen. In der ersten Erprobungsstufe wurde der Einsatz der Diskussionsforen in Verbindung mit den Lernfällen von den Studierenden und Lehrenden als sinnvolle Ergänzung betrachtet. In zukünftigen Einsatzszenarien sollte eine Messung des studentischen Lernerfolgs mit dieser Methode erfolgen.

Coupling of the Magnetosphere-Ionosphere/Thermosphere and Oxygen Outflow-- MIT Mission

Science.gov (United States)

Fu, S.

2017-12-01

The goal of the MIT mission is to understand the coupling of the magnetosphere and ionosphere from the prospective of particles. It will focus on the outflow of the ionosphere particles (mainly oxygen ions) from the Earth, including the acceleration mechanisms of oxygen ions and their relative importance in different regions, the importance of these ions while transferred into the magnetosphere and the roles they played in magnetosphere activities. A constellation of four satellites orbiting at three elliptical orbits will provide the unique opportunities to observed there ions at three different altitude with temporal changes of the flux of these particles and the magnetic field environments. The conceptual design of the spacecraft and a summary of the payload will be presented. The MIT mission was selected as one of the five candidates for the upcoming mission plan in China.

Detection of Tospoviruses in Ornamental Plants in Hobby Gardens and Landscaping Areas in Adalar District of Istanbul Province

Directory of Open Access Journals (Sweden)

Fatma Şafak

2017-09-01

Full Text Available This study was conducted in order to detect Tomato spotted wilt virus (TSWV, Irish yellow spot virus (IYSV and Impatients necrotic spot virus (INSV in ornamental plants growing in hobby gardens and landscaping areas in Adalar district (Büyükada, Heybeliada, Kınalıada and Burgazada of Istanbul province between 2015 and 2016. During the surveys carried out in that district, the samples were collected from both simptomatologically suspicious ornamental plants and the plants which did not show any symptoms. All of the collected samples (n=150 were firstly tested by Double Antibody Sandwich (DAS ELISA and none of the samples were found to be infected with TSWV and INSV. The samples detected to be positive with IYSV by ELISA tests were then used in RT-PCR studies. At the RT-PCR using the IYSV-465c; IYSV-239f primer pair, a band with a size of 240 bp was observed for Pittosporum tobira and Hydrangea macrophylla. Therefore, the presence of IYSV infection in Adalar was also confirmed molecularly.

Technological Aspects of Creating Large-size Optical Telescopes

Directory of Open Access Journals (Sweden)

V. V. Sychev

2015-01-01

Full Text Available A concept of the telescope creation, first of all, depends both on a choice of the optical scheme to form optical radiation and images with minimum losses of energy and information and on a choice of design to meet requirements for strength, stiffness, and stabilization characteristics in real telescope operation conditions. Thus, the concept of creating large-size telescopes, certainly, involves the use of adaptive optics methods and means.The level of technological capabilities to realize scientific and engineering ideas define a successful development of large-size optical telescopes in many respects. All developers pursue the same aim that is to raise an amount of information by increasing a main mirror diameter of the telescope.The article analyses the adaptive telescope designs developed in our country. Using a domestic ACT-25 telescope as an example, it considers creation of large-size optical telescopes in terms of technological aspects. It also describes the telescope creation concept features, which allow reaching marginally possible characteristics to ensure maximum amount of information.The article compares a wide range of large-size telescopes projects. It shows that a domestic project to create the adaptive ACT-25 super-telescope surpasses its foreign counterparts, and there is no sense to implement Euro50 (50m and OWL (100m projects.The considered material gives clear understanding on a role of technological aspects in development of such complicated optic-electronic complexes as a large-size optical telescope. The technological criteria of an assessment offered in the article, namely specific informational content of the telescope, its specific mass, and specific cost allow us to reveal weaknesses in the project development and define a reserve regarding further improvement of the telescope.The analysis of results and their judgment have shown that improvement of optical largesize telescopes in terms of their maximum

Neutrino telescopes in the World

International Nuclear Information System (INIS)

Ernenwein, J.-P.

2007-01-01

Neutrino astronomy has rapidly developed these last years, being the only way to get specific and reliable information about astrophysical objects still poorly understood.Currently two neutrino telescopes are operational in the World: BAIKAL, in the lake of the same name in Siberia, and AMANDA, in the ices of the South Pole. Two telescopes of the same type are under construction in the Mediterranean Sea: ANTARES and NESTOR. All these telescopes belong to a first generation, with an instrumented volume smaller or equal to 0.02 km3. Also in the Mediterranean Sea, the NEMO project is just in its starting phase, within the framework of a cubic kilometer size neutrino telescope study. Lastly, the ICECUBE detector, with a volume reaching about 1 km3, is under construction on the site of AMANDA experiment, while an extension of the BAIKAL detector toward km3 is under study. We will present here the characteristics of these experiments, as well as the results of their observations

The Liverpool Telescope: rapid follow-up observation of targets of opportunity with a 2 m robotic telescope

International Nuclear Information System (INIS)

Gomboc, Andreja; Bode, Michael F.; Carter, David; Mundell, Carol G.; Newsam, Andrew; Smith, Robert J.; Steele, Iain A.

2004-01-01

The Liverpool Telescope, situated at Roque de los Muchachos Observatory, La Palma, Canaries, is the first 2-m, fully instrumented robotic telescope. It recently began observations. Among Liverpool Telescope's primary scientific goals is to monitor variable objects on all timescales from seconds to years. An additional benefit of its robotic operation is rapid reaction to unpredictable phenomena and their systematic follow up, simultaneous or coordinated with other facilities. The Target of Opportunity Programme of the Liverpool Telescope includes the prompt search for and observation of GRB and XRF counterparts. A special over-ride mode implemented for GRB/XRF follow-up enables observations commencing less than a minute after the alert, including optical and near infrared imaging and spectroscopy. In particular, the moderate aperture and rapid automated response make the Liverpool Telescope excellently suited to help solving the mystery of optically dark GRBs and for the investigation of currently unstudied short bursts and XRFs

Qanti-QG hermaphrodite mesons in the MIT bag model

International Nuclear Information System (INIS)

Barnes, T.; Close, F.E.; Viron, F. de

1982-10-01

It is suggested that hermaphrodite (qanti-qg) mesons could exist with rather light masses. The spectrum of the ground state nonets, Jsup(PC) = (0, 1, 2) -+ ; 1 -- is calculated in the MIT bag model including 0(αsub(s)) energy shifts. Hadronic transitions among these states are discussed, considering their possible production at LEAR and SPEAR and indicating some interesting decay signatures. (author)

ANTARES: The first undersea neutrino telescope

Science.gov (United States)

Ageron, M.; Aguilar, J. A.; Al Samarai, I.; Albert, A.; Ameli, F.; André, M.; Anghinolfi, M.; Anton, G.; Anvar, S.; Ardid, M.; Arnaud, K.; Aslanides, E.; Assis Jesus, A. C.; Astraatmadja, T.; Aubert, J.-J.; Auer, R.; Barbarito, E.; Baret, B.; Basa, S.; Bazzotti, M.; Becherini, Y.; Beltramelli, J.; Bersani, A.; Bertin, V.; Beurthey, S.; Biagi, S.; Bigongiari, C.; Billault, M.; Blaes, R.; Bogazzi, C.; de Botton, N.; Bou-Cabo, M.; Boudahef, B.; Bouwhuis, M. C.; Brown, A. M.; Brunner, J.; Busto, J.; Caillat, L.; Calzas, A.; Camarena, F.; Capone, A.; Caponetto, L.; Cârloganu, C.; Carminati, G.; Carmona, E.; Carr, J.; Carton, P. H.; Cassano, B.; Castorina, E.; Cecchini, S.; Ceres, A.; Chaleil, Th.; Charvis, Ph.; Chauchot, P.; Chiarusi, T.; Circella, M.; Compère, C.; Coniglione, R.; Coppolani, X.; Cosquer, A.; Costantini, H.; Cottini, N.; Coyle, P.; Cuneo, S.; Curtil, C.; D'Amato, C.; Damy, G.; van Dantzig, R.; de Bonis, G.; Decock, G.; Decowski, M. P.; Dekeyser, I.; Delagnes, E.; Desages-Ardellier, F.; Deschamps, A.; Destelle, J.-J.; di Maria, F.; Dinkespiler, B.; Distefano, C.; Dominique, J.-L.; Donzaud, C.; Dornic, D.; Dorosti, Q.; Drogou, J.-F.; Drouhin, D.; Druillole, F.; Durand, D.; Durand, R.; Eberl, T.; Emanuele, U.; Engelen, J. J.; Ernenwein, J.-P.; Escoffier, S.; Falchini, E.; Favard, S.; Fehr, F.; Feinstein, F.; Ferri, M.; Ferry, S.; Fiorello, C.; Flaminio, V.; Folger, F.; Fritsch, U.; Fuda, J.-L.; Galatá, S.; Galeotti, S.; Gay, P.; Gensolen, F.; Giacomelli, G.; Gojak, C.; Gómez-González, J. P.; Goret, Ph.; Graf, K.; Guillard, G.; Halladjian, G.; Hallewell, G.; van Haren, H.; Hartmann, B.; Heijboer, A. J.; Heine, E.; Hello, Y.; Henry, S.; Hernández-Rey, J. J.; Herold, B.; Hößl, J.; Hogenbirk, J.; Hsu, C. C.; Hubbard, J. R.; Jaquet, M.; Jaspers, M.; de Jong, M.; Jourde, D.; Kadler, M.; Kalantar-Nayestanaki, N.; Kalekin, O.; Kappes, A.; Karg, T.; Karkar, S.; Karolak, M.; Katz, U.; Keller, P.; Kestener, P.; Kok, E.; Kok, H.; Kooijman, P.; Kopper, C.; Kouchner, A.; Kretschmer, W.; Kruijer, A.; Kuch, S.; Kulikovskiy, V.; Lachartre, D.; Lafoux, H.; Lagier, P.; Lahmann, R.; Lahonde-Hamdoun, C.; Lamare, P.; Lambard, G.; Languillat, J.-C.; Larosa, G.; Lavalle, J.; Le Guen, Y.; Le Provost, H.; Levansuu, A.; Lefèvre, D.; Legou, T.; Lelaizant, G.; Lévéque, C.; Lim, G.; Lo Presti, D.; Loehner, H.; Loucatos, S.; Louis, F.; Lucarelli, F.; Lyashuk, V.; Magnier, P.; Mangano, S.; Marcel, A.; Marcelin, M.; Margiotta, A.; Martinez-Mora, J. A.; Masullo, R.; Mazéas, F.; Mazure, A.; Meli, A.; Melissas, M.; Migneco, E.; Mongelli, M.; Montaruli, T.; Morganti, M.; Moscoso, L.; Motz, H.; Musumeci, M.; Naumann, C.; Naumann-Godo, M.; Neff, M.; Niess, V.; Nooren, G. J. L.; Oberski, J. E. J.; Olivetto, C.; Palanque-Delabrouille, N.; Palioselitis, D.; Papaleo, R.; Păvălaş, G. E.; Payet, K.; Payre, P.; Peek, H.; Petrovic, J.; Piattelli, P.; Picot-Clemente, N.; Picq, C.; Piret, Y.; Poinsignon, J.; Popa, V.; Pradier, T.; Presani, E.; Prono, G.; Racca, C.; Raia, G.; van Randwijk, J.; Real, D.; Reed, C.; Réthoré, F.; Rewiersma, P.; Riccobene, G.; Richardt, C.; Richter, R.; Ricol, J. S.; Rigaud, V.; Roca, V.; Roensch, K.; Rolin, J.-F.; Rostovtsev, A.; Rottura, A.; Roux, J.; Rujoiu, M.; Ruppi, M.; Russo, G. V.; Salesa, F.; Salomon, K.; Sapienza, P.; Schmitt, F.; Schöck, F.; Schuller, J.-P.; Schüssler, F.; Sciliberto, D.; Shanidze, R.; Shirokov, E.; Simeone, F.; Sottoriva, A.; Spies, A.; Spona, T.; Spurio, M.; Steijger, J. J. M.; Stolarczyk, Th.; Streeb, K.; Sulak, L.; Taiuti, M.; Tamburini, C.; Tao, C.; Tasca, L.; Terreni, G.; Tezier, D.; Toscano, S.; Urbano, F.; Valdy, P.; Vallage, B.; van Elewyck, V.; Vannoni, G.; Vecchi, M.; Venekamp, G.; Verlaat, B.; Vernin, P.; Virique, E.; de Vries, G.; van Wijk, R.; Wijnker, G.; Wobbe, G.; de Wolf, E.; Yakovenko, Y.; Yepes, H.; Zaborov, D.; Zaccone, H.; Zornoza, J. D.; Zúñiga, J.

2011-11-01

The ANTARES Neutrino Telescope was completed in May 2008 and is the first operational Neutrino Telescope in the Mediterranean Sea. The main purpose of the detector is to perform neutrino astronomy and the apparatus also offers facilities for marine and Earth sciences. This paper describes the design, the construction and the installation of the telescope in the deep sea, offshore from Toulon in France. An illustration of the detector performance is given.

ANTARES: The first undersea neutrino telescope

International Nuclear Information System (INIS)

Ageron, M.; Aguilar, J.A.; Al Samarai, I.; Albert, A.; Ameli, F.; Andre, M.; Anghinolfi, M.; Anton, G.; Anvar, S.; Ardid, M.; Arnaud, K.; Aslanides, E.; Assis Jesus, A.C.; Astraatmadja, T.; Aubert, J.-J.; Auer, R.; Barbarito, E.; Baret, B.

2011-01-01

The ANTARES Neutrino Telescope was completed in May 2008 and is the first operational Neutrino Telescope in the Mediterranean Sea. The main purpose of the detector is to perform neutrino astronomy and the apparatus also offers facilities for marine and Earth sciences. This paper describes the design, the construction and the installation of the telescope in the deep sea, offshore from Toulon in France. An illustration of the detector performance is given.

Initiation of a phase-I trial of neutron capture therapy at the MIT research reactor

International Nuclear Information System (INIS)

Harling, O.K.; Bernard, J.A.; Yam, Chun-Shan

1995-01-01

The Massachusetts Institute of Technology (MIT), the New England Medical Center (NEMC), and Boston University Medical Center (BUMC) initiated a phase-1 trial of boron neutron capture therapy (BNCT) on September 6, 1994, at the 5-MW(thermal) MIT research reactor (MITR). A novel form of experimental cancer therapy, BNCT is being developed for certain types of highly malignant brain tumors such as glioblastoma and melanoma. The results of the phase-1 trials on patients with tumors in the legs or feet are described

The Dutch Open Telescope: History, Status, Prospects

NARCIS (Netherlands)

Rutten, R.J.

1999-01-01

After many years of persistent telescope design and telescope construction, R.H. Hammerschlag has installed his Dutch Open Telescope (DOT) on La Palma. I brie y review its history and design. The future of optical solar physics at Utrecht hinges on a recently-funded three- year DOT science

A virtual reality environment for telescope operation

Science.gov (United States)

Martínez, Luis A.; Villarreal, José L.; Ángeles, Fernando; Bernal, Abel

2010-07-01

Astronomical observatories and telescopes are becoming increasingly large and complex systems, demanding to any potential user the acquirement of great amount of information previous to access them. At present, the most common way to overcome that information is through the implementation of larger graphical user interfaces and computer monitors to increase the display area. Tonantzintla Observatory has a 1-m telescope with a remote observing system. As a step forward in the improvement of the telescope software, we have designed a Virtual Reality (VR) environment that works as an extension of the remote system and allows us to operate the telescope. In this work we explore this alternative technology that is being suggested here as a software platform for the operation of the 1-m telescope.

Autolytic activity of human calpain 7 is enhanced by ESCRT-III-related protein IST1 through MIT-MIM interaction.

Science.gov (United States)

Osako, Yohei; Maemoto, Yuki; Tanaka, Ryohei; Suzuki, Hironori; Shibata, Hideki; Maki, Masatoshi

2010-11-01

Calpain 7, a mammalian ortholog of yeast Cpl1/Rim13 and fungal PalB, is an atypical calpain that lacks a penta-EF-hand domain. Previously, we reported that a region containing a tandem repeat of microtubule-interacting and transport (MIT) domains in calpain 7 interacts with a subset of endosomal sorting complex required for transport (ESCRT)-III-related proteins, suggesting involvement of calpain 7 in the ESCRT system. Although yeast and fungal calpains are thought to be involved in alkaline adaptation via limited proteolysis of specific transcription factors, proteolytic activity of calpain 7 has not been demonstrated yet. In this study, we investigated the interaction between calpain 7 and a newly reported ESCRT-III family member, increased sodium tolerance-1 (IST1), which possesses two different types of MIT-interacting motifs (MIM1 and MIM2). We found that glutathione-S-transferase (GST)-fused tandem MIT domains of calpain 7 (calpain 7MIT) pulled down FLAG-tagged IST1 expressed in HEK293T cells. Coimmunoprecipitation assays with various deletion or point mutants of epitope-tagged calpain 7 and IST1 revealed that both repetitive MIT domains and MIMs are required for efficient interaction. Direct MIT-MIM binding was confirmed by a pulldown experiment with GST-fused IST1 MIM and purified recombinant calpain 7MIT. Furthermore, we found that the GST-MIM protein enhances the autolysis of purified Strep-tagged monomeric green fluorescent protein (mGFP)-fused calpain 7 (mGFP-calpain 7-Strep). The autolysis was almost completely abolished by 10 mmN-ethylmaleimide but only partially inhibited by 1 mm leupeptin or E-64. The putative catalytic Cys290-substituted mutant (mGFP-calpain 7(C290S)-Strep) showed no autolytic activity. These results demonstrate for the first time that human calpain 7 is proteolytically active, and imply that calpain 7 is activated in the ESCRT system. © 2010 The Authors Journal compilation © 2010 FEBS.

Peniskarzinom mit exulzerierten Lymphknotenmetastasen links inguinal

Directory of Open Access Journals (Sweden)

Presich K

2003-01-01

Full Text Available Im Oktober 2001 wurde ein 53jähriger Patient mit ausgedehnten exulzerierten Lymphknotenmetastasen rechts inguinal an einer auswärtigen chirurgischen Abteilung vorgestellt. Im Rahmen der Durchuntersuchung fand sich eine verhärtete, von einem nicht retrahierbaren Präputium verdeckte Glans als mögliches Primum. Eine Circumcision sowie Biopsie aus der Glans ergaben das histologische Ergebnis eines invasiven, schwach verhornenden Plattenepithelkarzinoms mittleren Differenzierungsgrades (G2-G3. In einer Unterbauch-Computertomographie wurde rechts inguinal ein ausgedehnter, ca. 10 cm messender, teils solider, teils nekrotischer Prozeß, bis an die großen Gefäße heranreichend, beschrieben. Die linke Leiste war unauffällig.

LSST telescope and site status

Science.gov (United States)

Gressler, William J.

2016-07-01

The Large Synoptic Survey Telescope (LSST) Project1 received its construction authorization from the National Science Foundation in August 2014. The Telescope and Site (T and S) group has made considerable progress towards completion in subsystems required to support the scope of the LSST science mission. The LSST goal is to conduct a wide, fast, deep survey via a 3-mirror wide field of view optical design, a 3.2-Gpixel camera, and an automated data processing system. The summit facility is currently under construction on Cerro Pachón in Chile, with major vendor subsystem deliveries and integration planned over the next several years. This paper summarizes the status of the activities of the T and S group, tasked with design, analysis, and construction of the summit and base facilities and infrastructure necessary to control the survey, capture the light, and calibrate the data. All major telescope work package procurements have been awarded to vendors and are in varying stages of design and fabrication maturity and completion. The unique M1M3 primary/tertiary mirror polishing effort is completed and the mirror now resides in storage waiting future testing. Significant progress has been achieved on all the major telescope subsystems including the summit facility, telescope mount assembly, dome, hexapod and rotator systems, coating plant, base facility, and the calibration telescope. In parallel, in-house efforts including the software needed to control the observatory such as the scheduler and the active optics control, have also seen substantial advancement. The progress and status of these subsystems and future LSST plans during this construction phase are presented.

Automatic Photoelectric Telescope Service

International Nuclear Information System (INIS)

Genet, R.M.; Boyd, L.J.; Kissell, K.E.; Crawford, D.L.; Hall, D.S.; BDM Corp., McLean, VA; Kitt Peak National Observatory, Tucson, AZ; Dyer Observatory, Nashville, TN)

1987-01-01

Automatic observatories have the potential of gathering sizable amounts of high-quality astronomical data at low cost. The Automatic Photoelectric Telescope Service (APT Service) has realized this potential and is routinely making photometric observations of a large number of variable stars. However, without observers to provide on-site monitoring, it was necessary to incorporate special quality checks into the operation of the APT Service at its multiple automatic telescope installation on Mount Hopkins. 18 references

The ATHENA telescope and optics status

Science.gov (United States)

Bavdaz, Marcos; Wille, Eric; Ayre, Mark; Ferreira, Ivo; Shortt, Brian; Fransen, Sebastiaan; Collon, Maximilien; Vacanti, Giuseppe; Barriere, Nicolas; Landgraf, Boris; Haneveld, Jeroen; van Baren, Coen; Zuknik, Karl-Heintz; Della Monica Ferreira, Desiree; Massahi, Sonny; Christensen, Finn; Krumrey, Michael; Burwitz, Vadim; Pareschi, Giovanni; Spiga, Daniele; Valsecchi, Giuseppe; Vernani, Dervis; Oliver, Paul; Seidel, André

2017-08-01

The work on the definition and technological preparation of the ATHENA (Advanced Telescope for High ENergy Astrophysics) mission continues to progress. In parallel to the study of the accommodation of the telescope, many aspects of the X-ray optics are being evolved further. The optics technology chosen for ATHENA is the Silicon Pore Optics (SPO), which hinges on technology spin-in from the semiconductor industry, and uses a modular approach to produce large effective area lightweight telescope optics with a good angular resolution. Both system studies and the technology developments are guided by ESA and implemented in industry, with participation of institutional partners. In this paper an overview of the current status of the telescope optics accommodation and technology development activities is provided.

Hard x-ray telescope mission

DEFF Research Database (Denmark)

Gorenstein, P.; Worrall, D.; Joensen, K.D.

1996-01-01

The Hard X-Ray Telescope was selected for study as a possible new intermediate size mission for the early 21st century. Its principal attributes are: (1) multiwavelength observing with a system of focussing telescopes that collectively observe from the UV to over 1 MeV, (2) much higher sensitivity...

Gebrauch von Komplementärmedizin bei Patienten mit metastasierendem Melanom unter Therapie mit Ipilimumab innerhalb einer klinischen Studie.

Science.gov (United States)

Huebner, Jutta; Mohr, Peter; Simon, Jan-Christoph; Fluck, Michael; Berking, Carola; Zimmer, Lisa; Loquai, Carmen

2016-05-01

In Deutschland wenden 40-90 % aller Krebspatienten Methoden der komplementären and alternativen Medizin (KAM) an. Bis dato gibt es kein Datenmaterial zum Einsatz der KAM bei Melanompatienten. Das Ziel unserer Studie war es, Daten über den Gebrauch, die Informationsquellen und Ziele von Patienten mit metastasierendem Melanom zu erfassen. Einhundertsechsundfünfzig Patienten aus 25 Studienzentren nahmen an der DecOG-MM-PAL Multibasket Studie teil. Die beteiligten Personen wurden auch gebeten, an einer Nebenstudie teilzunehmen, die ihren Gebrauch von KAM erfassen sollte. Dazu wurde während der Behandlung ein standardisierter Fragebogen zu genau festgelegten Zeitpunkten ausgeteilt. Insgesamt gingen 55 Fragebögen von 32 (21 %) Melanompatienten ein. Von diesen gaben 17 (53 %) ein Interesse an KAM an, und sieben (22 %) machten von KAM Gebrauch. Die Hauptinformationsquellen (31 %) waren Familienmitglieder und Freunde, gefolgt von Ärzten (19 %). Die Hauptgründe für die Anwendung von KAM waren die Stärkung des Immunsystems (41 %) und des Körpers (34 %). Nahrungsergänzungsmittel (Vitamine und Spurenelemente) wurden am häufigsten angewendet (28 %). Eine relativ hohe Anzahl an Patienten mit metastasierendem Melanom machte trotz Teilnahme an einer klinischen Studie von KAM Gebrauch. Wechselwirkungen könnten durch biologisch basierte KAM auftreten, und hier besonders bei immunmodulierenden KAM- Strategien. Um Risiken zu vermeiden, sollte die Kommunikation zwischen den Ärzten und den Patienten verbessert werden. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

[Cardiodoron® bei Patienten mit Schlafstörungen - Ergebnisse einer prospektiven Beobachtungsstudie].

Science.gov (United States)

Rother, Claudia; Schnelle, Martin

Hintergrund: Schlafstörungen gehören zu den häufigsten gesundheitlichen Problemen der heutigen Zeit. Stress und die dadurch bedingte innere Anspannung sowie eine unrhythmische Lebensführung z.B. durch Schichtarbeit sind bekannte auslösende Faktoren. Weniger bekannt ist, dass auch funktionelle Herz-Kreislauf-Beschwerden zu Störungen des Schlafs führen können und dass deren Behandlung zu einer Verbesserung der Schlafqualität beiträgt. Ganzheitlich betrachtet geht es daher um die Wiederherstellung einer gesunden Rhythmik, insbesondere des Herz-/Atem- sowie des Schlaf-Wach-Rhythmus, die Cardiodoron®, eine Heilpflanzenkomposition aus Primula veris, Hyoscyamus niger und Onopordum acanthium, unterstützt. Patienten und Methoden: Mittels einer prospektiven, multizentrischen Beobachtungsstudie sollte ermittelt werden, wie sich funktionelle Herz-Kreislauf-Beschwerden und/oder Schlafstörungen unter der Behandlung mit Cardiodoron® (Dilution) über 3-6 Monate entwickeln. Im Zeitraum von September 2009 bis März 2012 dokumentierten 92 Ärzte 501 Patienten, von denen 380 über Schlafstörungen klagten und deren Daten in dieser Publikation näher betrachtet werden. Nach einer Aufnahmeuntersuchung erfolgte nach 90 Tagen eine Abschlussuntersuchung und bei Fortführung der Therapie nach nochmals 90 Tagen eine Follow-up-Untersuchung. Neben 30 ärztlicherseits bewerteten Symptomen beurteilten die Patienten ihr Befinden mittels Pittsburgh Sleep Quality Index (PSQI) nach Buysse und der Beschwerden-Liste nach von Zerssen (B-L und B-L'). Ergebnisse: Unter der Cardiodoron®-Therapie gingen bei guter Verträglichkeit sowohl die Ausprägung der Schlafstörungen (um 65% von 2,0 auf 0,7 Punkte) als auch die erfassten 30 Symptome (um 59% von 24,3 auf 9,9 Punkte) deutlich zurück (p mit Schlafstörungen (mit oder ohne funktionelle Herz-Kreislauf-Beschwerden) kann die Ausprägung der Beschwerden mit Cardiodoron® deutlich gesenkt werden. Cardiodoron® ist gut verträglich. © 2016 S

Energiemessungen bei Aspergillus niger mit Hilfe eines automatischen Mikro-Kompensations-Calorimeters

NARCIS (Netherlands)

Algera, Leendert

1932-01-01

Beschrieben wurde ein Calorimeter. Das Prinzip der Warmemessung besteht darin, dasz die entwickelte Wärme, sobald sie entsteht, durch eine entsprechende Kältemenge kompensiert wird. Sobald die Temperatur des Kulturgefaszes ein wenig ansteigt, wird trockne Luft gepumpt durch ein mit Wasser gefulltes

Metacognitive Interpersonal Therapy in group (MIT-G) for young adults with personality disorders: A pilot randomized controlled trial.

Science.gov (United States)

Popolo, Raffaele; MacBeth, Angus; Canfora, Flaviano; Rebecchi, Daniela; Toselli, Cecilia; Salvatore, Giampaolo; Dimaggio, Giancarlo

2018-04-06

Young adults with personality disorders (PD) other than borderline are in urgent need of validated treatments to help them in managing important life transitions. Therapeutic interventions focused upon social and interpersonal difficulties may facilitate these individuals in maximizing opportunities for employment, forming stable romantic relationships, and belong to social groups. It is also important that they are offered evidence-based, first-line time-limited treatments in order to maximize effectiveness and reduce costs. We developed a 16-session programme of group-based Metacognitive Interpersonal Therapy (MIT-G) including psychoeducation on the main interpersonal motives, an experiential component enabling practice of awareness of mental states; and use of mentalistic knowledge for purposeful problem-solving. We report a feasibility, acceptability, and clinical significance randomized clinical trial. Participants meeting inclusion criteria were randomized to receive MIT-G (n = 10) or waiting list+TAU (n = 10). Dropout rate was low and session attendance high (92.19%). Participants in the MIT-G arm had symptomatic and functional improvements consistent with large effect sizes. In the MIT-G arm similarly large effects were noted for increased capacity to understand mental states and regulate social interactions using mentalistic knowledge. Results were sustained at follow-up. Our findings suggest potential for applying MIT-G in larger samples to further test its effectiveness in reducing PD-related symptoms and problematic social functioning. © 2018 The British Psychological Society.

21 CFR 886.5870 - Low-vision telescope.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Low-vision telescope. 886.5870 Section 886.5870...) MEDICAL DEVICES OPHTHALMIC DEVICES Therapeutic Devices § 886.5870 Low-vision telescope. (a) Identification. A low-vision telescope is a device that consists of an arrangement of lenses or mirrors intended for...

Axial turbine with underwater generator for energy recovery; Axialturbine mit Unterwassergenerator zur Energierueckgewinnung

Energy Technology Data Exchange (ETDEWEB)

Welzel, B. [Stuttgart Univ. (Germany). Inst. fuer Stroemungsmechanik und Hydraulische Stroemungsmaschinen

1997-12-31

Within the framework of a project sponsored by the Stiftung Energieforschung Baden-Wuerttemberg, an axial turbine was developed as a flash evaporator, which permits energy recovery in all sectors where liquids in piping undergoes pressure relaxation. A specific feature of this turbine is that it forms part, complete with generator, of a single pipeline and that it does not cause any pressure variations worth mentioning in case of mains failure. The report describes the turbine, its advantages, and a pilot operation carried out with a prototype. The turbine`s performance is compared with a return pump. Further, the optimization of the hydraulic design by computer and the results of a market analysis are dealt with. (orig.) [Deutsch] Im Rahmen einer von der Stiftung Energieforschung Baden-Wuerttemberg gefoerderten Neuentwicklung wurde eine Axialturbine als Entspannungsturbine entwickelt, mit der eine Energierueckgewinnung in allen Bereichen erfolgen kann, in denen Fluessigkeiten in Rohrleitungssystemen entspannt werden. Die Turbine zeichnet sich unter anderem dadurch aus, dass sie komplett, inklusive Generator, innerhalb einer Rohrleitung angeordnet ist und bei Netzausfall keine nennenswerte Druckschwankung erzeugt. Es werden die Turbine, deren Vorteile sowie der mit einem Prototypen durchgefuehrte Betriebsversuch beschrieben. Weiterhin werden ein Vergleich des Betriebsverhaltens mit einer rueckwaertslaufenden Pumpe, die rechnerische Optimierung der hydraulischen Formgebung sowie die Ergebnisse einer Marktanalyse behandelt. (orig.)

Optische Bildgebung der Autoimmunarthritis mit DiD markierten Leukozyten

OpenAIRE

Kau, Julia

2008-01-01

Zielsetzung: Ziel der vorliegenden Studie war es, zu untersuchen, ob die Optische Bildgebung nach Injektion von ex vivo DiD markierten Leukozyten, in der Lage ist, eine Entzündung der Synovialmembran in Ratten mit einer Antigen-induzierten Monoarthritis des rechten Kniegelenkes aufzudecken. Die Optische Bildgebung wurde auf ihre Fähigkeit zur Unterscheidung zwischen arthritischen und gesunden Kniegelenken und zwischen nichttherapierten und Kortison-therapierten Kniegelenken unt...

Elektrochemisches Verhalten von Lithium-Schwefel-Zellen mit unterschiedlicher Kathodenstruktur

OpenAIRE

Scherr, Christopher

2014-01-01

Die elektrochemische Energiespeicherung ist in der Elektromobilität und dezentralen Energieversorgung einer der wichtigsten Bausteine. Der Lithium-Schwefel-Akkumulator mit seinen hohen theoretischen Kennwerte hat das Potential in Zukunft, hierbei eine gewichtige Rolle zu spielen. Je nach Zusammensetzung und Herstellung der Kathode variieren die Kennwerte jedoch sehr stark. In dieser Arbeit wurde der Einfluss der Kathodenstruktur und -zusammensetzung auf die Kapazität und Lebensdauer untersuch...

Comments on the MIT Assessment of the Mars One Plan

Science.gov (United States)

Jones, Harry W.

2015-01-01

The MIT assessment of the Mars One mission plan reveals design assumptions that would cause significant difficulties. Growing crops in the crew chamber produces excessive oxygen levels. The assumed in-situ resource utilization (ISRU) equipment has too low a Technology Readiness Level (TRL). The required spare parts cause a large and increasing launch mass logistics burden. The assumed International Space Station (ISS) Environmental Control and Life Support (ECLS) technologies were developed for microgravity and therefore are not suitable for Mars gravity. Growing food requires more mass than sending food from Earth. The large number of spares is due to the relatively low reliability of ECLS and the low TRL of ISRU. The Mars One habitat design is similar to past concepts but does not incorporate current knowledge. The MIT architecture analysis tool for long-term settlements on the Martian surface includes an ECLS system simulation, an ISRU sizing model, and an analysis of required spares. The MIT tool showed the need for separate crop and crew chambers, the large spare parts logistics, that crops require more mass than Earth food, and that more spares are needed if reliability is lower. That ISRU has low TRL and ISS ECLS was designed for microgravity are well known. Interestingly, the results produced by the architecture analysis tool - separate crop chamber, large spares mass, large crop chamber mass, and low reliability requiring more spares - were also well known. A common approach to ECLS architecture analysis is to build a complex model that is intended to be all-inclusive and is hoped will help solve all design problems. Such models can struggle to replicate obvious and well-known results and are often unable to answer unanticipated new questions. A better approach would be to survey the literature for background knowledge and then directly analyze the important problems.

Scientific management of Space Telescope

Science.gov (United States)

Odell, C. R.

1981-01-01

A historical summay is given on the science management of the Space Telescope, the inception of which began in 1962, when scientists and engineers first recommended the development of a nearly diffraction limited substantial-size optical telescope. Phase A, the feasibility requirements generation phase, began in 1971 and consisted largely of NASA scientists and a NASA design. Phase B, the preliminary design phase, established a tiered structure of scientists, led by the Large Space Telescope operations and Management Work Group. A Mission Operations Working Group headed six instrument definition teams to develop the essential instrument definitions. Many changes took place during Phase B, before design and development, which began in 1978 and still continues today.

[Homöopathisch-phytotherapeutische Behandlung des Reizdarmsyndroms mit Magen-Darm-Entoxin N®: Eine Anwendungsbeobachtung].

Science.gov (United States)

Märtens, Diane; Range, Natasha; Günnewich, Nils; Gruber, Nicola; Schmidt, Stefan

Hintergrund: In dieser Anwendungsbeobachtung wird zum ersten Mal die Behandlung des Reizdarmsyndroms (RDS) mit einem homöopathisch-phytotherapeutischen Komplexpräparat beschrieben. Methodik: Ziel der 6-wöchigen Therapie mit dem Magen-Darm-Entoxin N® war die Reduzierung der RDS-Symptomatik sowie die Verbesserung der Lebensqualität. Zielkriterien waren die Veränderungen in der Irritable Bowel Syndrome - Severity Scoring System (IBS-SSS) und der Irritable Bowel Syndrome - Quality-of-Life Scale (IBS-QoL). Die Patient/innen (N = 41; Alter 44,0 ± 15,74 Jahre) wurden zu gleichen Teilen in einer Hausarztpraxis (N = 20) und einer Heilpraktikerpraxis (N = 21) rekrutiert. Ergebnisse: Der IBS-QoL-Score verringerte sich signifikant (prä: 35,9 ± 16,3; post: 20,1 ± 13,4; t = 8,504; p mit einer Effektstärke von d = 1,24. Die Neben- und Wechselwirkungen waren minimal und signifikante Unterschiede zwischen beiden Praxen wurden nicht gefunden. Schlussfolgerungen: Magen-Darm-Entoxin N® ist eine sichere und sinnvolle Therapieoption bei der Behandlung des RDS. Allerdings sollten randomisierte kontrollierte Studien folgen, um die Spezifizität der Ergebnisse dieser Anwendungsbeobachtung zu stützen. © 2017 S. Karger GmbH, Freiburg.

Remote secure observing for the Faulkes Telescopes

Science.gov (United States)

Smith, Robert J.; Steele, Iain A.; Marchant, Jonathan M.; Fraser, Stephen N.; Mucke-Herzberg, Dorothea

2004-09-01

Since the Faulkes Telescopes are to be used by a wide variety of audiences, both powerful engineering level and simple graphical interfaces exist giving complete remote and robotic control of the telescope over the internet. Security is extremely important to protect the health of both humans and equipment. Data integrity must also be carefully guarded for images being delivered directly into the classroom. The adopted network architecture is described along with the variety of security and intrusion detection software. We use a combination of SSL, proxies, IPSec, and both Linux iptables and Cisco IOS firewalls to ensure only authenticated and safe commands are sent to the telescopes. With an eye to a possible future global network of robotic telescopes, the system implemented is capable of scaling linearly to any moderate (of order ten) number of telescopes.

Structural Fine-Tuning of MIT-Interacting Motif 2 (MIM2) and Allosteric Regulation of ESCRT-III by Vps4 in Yeast.

Science.gov (United States)

Kojima, Rieko; Obita, Takayuki; Onoue, Kousuke; Mizuguchi, Mineyuki

2016-06-05

The endosomal sorting complex required for transport (ESCRT) facilitates roles in membrane remodeling, such as multivesicular body biogenesis, enveloped virus budding and cell division. In yeast, Vps4 plays a crucial role in intraluminal vesicle formation by disassembling ESCRT proteins. Vps4 is recruited by ESCRT-III proteins to the endosomal membrane through the interaction between the microtubule interacting and trafficking (MIT) domain of Vps4 and the C-terminal MIT-interacting motif (MIM) of ESCRT-III proteins. Here, we have determined the crystal structure of Vps4-MIT in a complex with Vps20, a member of ESCRT-III, and revealed that Vps20 adopts a unique MIM2 conformation. Based on structural comparisons with other known MIM2s, we have refined the consensus sequence of MIM2. We have shown that another ESCRT-III protein, Ist1, binds to Vps4-MIT via its C-terminal MIM1 with higher affinity than Vps2, but lacks MIM2 by surface plasmon resonance. Surprisingly, the Ist1 MIM1 competed with the MIM2 of Vfa1, a regulator of Vps4, for binding to Vps4-MIT, even though these MIMs bind in non-overlapping sites on the MIT. These findings provide insight into the allosteric recognition of MIMs of ESCRT-III by Vps4 and also the regulation of ESCRT machinery at the last step of membrane remodeling. Copyright © 2016 Elsevier Ltd. All rights reserved.

Single particle detecting telescope system

International Nuclear Information System (INIS)

Yamamoto, I.; Tomiyama, T.; Iga, Y.; Komatsubara, T.; Kanada, M.; Yamashita, Y.; Wada, T.; Furukawa, S.

1981-01-01

We constructed the single particle detecting telescope system for detecting a fractionally charged particle. The telescope consists of position detecting counters, wall-less multi-cell chambers, single detecting circuits and microcomputer system as data I/0 processor. Especially, a frequency of double particle is compared the case of the single particle detecting with the case of an ordinary measurement

Building the Hubble Space Telescope

International Nuclear Information System (INIS)

O'dell, C.R.

1989-01-01

The development of the design for the Hubble Space Telescope (HST) is discussed. The HST optical system is described and illustrated. The financial and policy issues related to the development of the HST are considered. The actual construction of the HST optical telescope is examined. Also, consideration is given to the plans for the HST launch

Lee Sang Gak Telescope (LSGT): A Remotely Operated Robotic Telescope for Education and Research at Seoul National University

Science.gov (United States)

Im, Myungshin; Choi, Changsu; Kim, Kihyun

2015-08-01

We introduce the Lee Sang Gak Telescope (LSGT), a remotely operated, robotic 0.43-meter telescope. The telescope was installed at the Siding Spring Observatory, Australia, in 2014 October, to secure regular and exclusive access to the dark sky and excellent atmospheric conditions in the southern hemisphere from the Seoul National University (SNU) campus. Here, we describe the LSGT system and its performance, present example images from early observations, and discuss a future plan to upgrade the system. The use of the telescope includes (i) long-term monitoring observations of nearby galaxies, active galactic nuclei, and supernovae; (ii) rapid follow-up observations of transients such as gamma-ray bursts and gravitational wave sources; and (iii) observations for educational activities at SNU. Based on observations performed so far, we find that the telescope is capable of providing images to a depth of R=21.5 mag (point source detection) at 5-σ with 15 min total integration time under good obs-erving conditions.

Untersuchung perturbativer und nichtperturbativer Struktur der Momente hadronischer Ereignisformvariablen mit den Experimenten JADE und OPAL

CERN Document Server

Pahl, Christoph Johannes

2007-01-01

In Hadronproduktionsdaten der e+e− - Vernichtungsexperimente JADE und OPAL messen wir die ersten f¨unf Momente von zw¨olf hadronischen Ereignisformvariablen bei Schwerpunktsenergien von 14 bis 207GeV. Aus dem Vergleich der QCD NLO-Vorhersage mit den mittels MC-Modellen um Hadronisierung korrigierten Daten erhalten wir den Referenzwert der starken Kopplung αs(MZ0) = 0.1254 ± 0.0007(stat.) ± 0.0010(exp.)+0.0009 −0.0023(had.)+0.0069 −0.0053(theo.) . F¨ur einige, insbesondere h¨ohere, Momente sind systematische Unzul¨anglichkeiten in der QCD NLO-Vorhersage erkenntlich. Simultane Fits an zwei Momente unter Annahme identischer Renormierungsskalen ergeben Skalenwerte von xμ=0.057 bis xμ=0.196 . Wir pr¨ufen Vorhersagen verschiedener nichtperturbativer Modelle. Aus der Single Dressed Gluon - N¨aherung ergibt sich eine perturbative Vorhersage in O(α5 s ) mit zu vernachl¨assigender Energiepotenzkorrektur, die den Mittelwert von Thrust auf Hadronniveau gut beschreibt mit αs(MZ0) = 0.1186 ± 0.0007(st...

Carbon Fiber Mirror for a CubeSat Telescope

Science.gov (United States)

Kim, Young-Soo; Jang, Jeong Gyun; Kim, Jihun; Nam, Uk Won

2017-08-01

Telescope mirrors made by carbon fibers have been increasingly used especially for space applications, and they may replace the traditional glass mirrors. Glass mirrors are easy to fabricate, but needed to be carefully handled as they are brittle. Other materials have also been considered for telescope mirrors, such as metals, plastics, and liquids even. However glass and glass ceramics are still commonly and dominantly used.Carbon fiber has mainly been used for mechanical supports like truss structure and telescope tubes, as it is stiff and light-weight. It can also be a good material for telescope mirrors, as it has additional merits of non-brittle and very low thermal expansion. Therefore, carbon fiber mirror would be suitable for space telescopes which should endure the harsh vibration conditions during launch.A light-weight telescope made by carbon fiber has been designed for a small satellite which would have much less weight than conventional ones. In this poster, mirror materials are reviewed, and a design of carbon fiber telescope is presented and discussed.

Renaissance des Mittelalters (Teil 1) : oder Alte Fragen mit Neuen Antworten

NARCIS (Netherlands)

drs. Frans van den Reep

2014-01-01

Man kann das Heute mit keiner Zeit vorher vergleichen? Zu schnell sind die Veränderungen, zu gravierend die technologischen Möglichkeiten der Digitalisierung, des Internets? Frans van der Reep nähert sich in vielen überraschenden Parallelen in der gesellschaftlichen Entwicklung dem Gestern und

A free market in telescope time?

Science.gov (United States)

Etherton, Jason; Steele, Iain A.; Mottram, Christopher J.

2004-09-01

As distributed systems are becoming more and more diverse in application there is a growing need for more intelligent resource scheduling. eSTAR Is a geographically distributed network of Grid-enabled telescopes, using grid middleware to provide telescope users with an authentication and authorisation method, allowing secure, remote access to such resources. The eSTAR paradigm is based upon this secure, single sign-on, giving astronomers or their agent proxies direct access to these telescopes. This concept, however, involves the complex issue of how to schedule observations stored within physically distributed media, on geographically distributed resources. This matter is complicated further by the varying degrees of constraints placed upon observations such as timeliness, atmospheric and meteorological conditions, and sky brightness to name a few. This paper discusses a free market approach to this scheduling problem, where astronomers are given credit, instead of time, from their respective TAGs to spend on telescopes as they see fit. This approach will ultimately provide a community-driven schedule, genuine indicators of the worth of specific telescope time and promote a more efficient use of that time, as well as demonstrating a 'survival of the fittest' type selection.

Collimator optimization studies for the new MIT epithermal neutron beam

International Nuclear Information System (INIS)

Riley, K.J.; Ali, S.J.; Harling, O.K.

2000-01-01

A patient collimator has been designed for the epithermal neutron facility now being commissioned at MIT. Collimator performance both in and out of field was evaluated using the Monte Carlo code MCNP. A two piece design that can accommodate different circular field sizes will be manufactured using a composite lead, epoxy, boron and lithium mixture. (author)

Elastolysen und Hauterkrankungen mit Verlust der elastischen Fasern.

Science.gov (United States)

Tronnier, Michael

2018-02-01

Die elastischen Fasern sind neben den kollagenen Fasern der wichtigste Bestandteil des Bindegewebsgerüstes der Haut. Eine Verminderung oder ein Verlust der elastischen Fasern ist bei einer Vielzahl von klinisch sich unterschiedlich präsentierenden Erkrankungen, hereditär oder erworben, beschrieben. Bei den Erkrankungen, die mit einer Entzündung einhergehen ist die Elastophagozytose ein wichtiges histologisches Merkmal. Die Therapie der Erkrankungen dieser Gruppe ist grundsätzlich schwierig. © 2018 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

Ground-Based Telescope Parametric Cost Model

Science.gov (United States)

Stahl, H. Philip; Rowell, Ginger Holmes

2004-01-01

A parametric cost model for ground-based telescopes is developed using multi-variable statistical analysis, The model includes both engineering and performance parameters. While diameter continues to be the dominant cost driver, other significant factors include primary mirror radius of curvature and diffraction limited wavelength. The model includes an explicit factor for primary mirror segmentation and/or duplication (i.e.. multi-telescope phased-array systems). Additionally, single variable models based on aperture diameter are derived. This analysis indicates that recent mirror technology advances have indeed reduced the historical telescope cost curve.

A Systems Approach to Healthcare Innovation Using the MIT Hacking Medicine Model.

Science.gov (United States)

Gubin, Tatyana A; Iyer, Hari P; Liew, Shirlene N; Sarma, Aartik; Revelos, Alex; Ribas, João; Movassaghi, Babak; Chu, Zen M; Khalid, Ayesha N; Majmudar, Maulik D; Lee, Christopher Xiang

2017-07-26

MIT Hacking Medicine is a student, academic, and community-led organization that uses systems-oriented "healthcare hacking" to address challenges around innovation in healthcare. The group has organized more than 80 events around the world that attract participants with diverse backgrounds. These participants are trained to address clinical needs from the perspective of multiple stakeholders and emphasize utility and implementation viability of proposed solutions. We describe the MIT Hacking Medicine model as a potential method to integrate collaboration and training in rapid innovation techniques into academic medical centers. Built upon a systems approach to healthcare innovation, the time-compressed but expertly guided nature of the events could enable more widely accessible preliminary training in systems-level innovation methodology, as well as creating a structured opportunity for interdisciplinary congregation and collaboration. Copyright © 2017 Elsevier Inc. All rights reserved.

Care of astronomical telescopes and accessories a manual for the astronomical observer and amateur telescope maker

CERN Document Server

Pepin, M Barlow

2005-01-01

Commercially-made astronomical telescopes are better and less expensive than ever before, and their optical and mechanical performance can be superb. When a good-quality telescope fails to perform as well as it might, the reason is quite probably that it needs a little care and attention! Here is a complete guide for anyone who wants to understand more than just the basics of astronomical telescopes and accessories, and how to maintain them in the peak of condition. The latest on safely adjusting, cleaning, and maintaining your equipment is combined with thoroughly updated methods from the old masters. Here, too, are details of choosing new and used optics and accessories, along with enhancements you can make to extend their versatility and useful lifetime. This book is for you. Really. Looking after an astronomical telescope isn't only for the experts - although there are some things that only an expert should attempt - and every serious amateur astronomer will find invaluable information here, gleaned from ...

GRANITE- A steroscopic imaging Chernkov telescope system

International Nuclear Information System (INIS)

Shubnell, M.; Akerlof, C.W.; Cawley, M.F.; Chantell, M.; Fegan, D.J.; Fennell, S.; O'Flaherty, K.S.; Freeman, S.; Frishman, D.; Gaidos, J.A.; Hagan, J.; Harris, K.; Hillas, A.M.; Kerrick, A.D.; Lamb, R.C.; Lappin, T.; Lawrence, M.A.; Levy, H.; Lewis, D.A.; Meyer, D.I.; Mohanty, G.; Punch, M.; Reynolds, P.T.; Rovero, A.C.; Sembroski, G.; Weaverdyck, C.; Weekes, T.C.; Whitaker, T.; Wilson, C.

1993-01-01

A second 10 meter class imaging telescope was constructed on Mt. Hopkins, Arizona, the site of the original 10 meter Whipple Cherenkov telescope. The twin telescope system with a 140 meter base line will allow both a reduction in the energy threshold and an improvement in the rejection of the hardonic background. The new telescope started operation in December 1991. With the final completion of the first installation stage (GRANITE I) during spring 92, it is now operating simultaneously with the orginal reflector. We describe in this paper design and construction of the new instrument and demonstrate the capability of the experiment to record coincident events

Overdenture dengan Pegangan Telescopic Crown

Directory of Open Access Journals (Sweden)

Pambudi Santoso

2014-06-01

Full Text Available Kaitan presisi merupakan alat retensi mekanis yang menghubungkan antara satu atau lebih pegangan gigi tiruan, yang bertujuan untuk menambah retensi dan/atau stabilisasi. Kaitan presisi dapat digunakan secara luas pada gigi tiruan cekat, gigi tiruan sebagian lepasan, overdenture, implant untuk retensi overdenture, dan protesa maksilo fasial. Overdenture dengan kaitan presisi dapat membantu dalam pembagian beban kunyah, meminimalkan trauma pada gigi pegangan dan jaringan lunak, meminimalkan resorbsi tulang, dan meningkatkan estetik dan pengucapan suara. Salah satu jenis dari kaitan presisi adalah telescopic crown, terdiri dari 2 macam mahkota, yaitu mahkota primer yang melekat secara permanen pada gigi penyangga, dan mahkota sekunder yang melekat pada gigi tiruan. Tujuan pemaparan kasus ini adalah untuk memberikan informasi tentang rehabilitasi pasien edentulous sebagian rahang atas dengan telescopic crown..  Pasien wanita berusia 45 tahun datang ke klinik prostodonsia RSGM Prof.Soedomo dengan keluhan ingin dibuatkan gigi tiruan. Pasien kehilangan gigi 11 12 15 16 17 21 22 24 25 26 dan 27 yang diindikasikan untuk pembuatan overdenture gigi tiruan sebagian lepasan (GTS kerangka logam dengan pegangan telescopic crown pada gigi 13 dan 14 dengan sistem parallel-sided crown. Tahap-tahap pembuatan telescopic crown yaitu mencetak model study dengan catatan gigit pendahuluan. Perawatan saluran dilakukan pada akar gigi 13, dilanjutkan pemasangan pasak fiber serta rewalling dinding bukal. Gigi 13 dan 14 dilakukan preparasi mahkota penuh, dilanjutkan dengan pencetakan model kerja untuk coping primer dan kerangka logam dengan metode double impression. Coping primer disementasi pada gigi penyangga, dilanjutkan pasang coba coping sekunder beserta kerangka logam. Selanjutnya dilakukan pencatatan gigit, pencetakan model kerja, penyusunan gigi dan pasang coba penyusunan gigi pada pasien. Prosedur dilanjutkan dengan proses di laboratorium, serta insersi pada

MR imaging of the lateral collateral ligaments after ankle sprain; Aussenbandrupturen des Sprunggelenkes - Darstellung mit der MRT vor und nach funktioneller Therapie

Energy Technology Data Exchange (ETDEWEB)

Grebe, P. [Klinik fuer Radiologie der Universitaetsklinik, Mainz (Germany); Kreitner, K.F. [Klinik fuer Radiologie der Universitaetsklinik, Mainz (Germany); Roeder, W. [Abt. fuer Chirurgie, St-Hildegardis-Krankenhaus, Mainz (Germany); Kersjes, W. [Klinik fuer Radiologie der Universitaetsklinik, Mainz (Germany); Hennes, R. [Abt. fuer Allgemein- und Unfallchirurgie, St. Josefshospital, Wiesbaden (Germany); Runkel, M. [Unfallchirurgische Klinik der Unversitaetsklinik, Mainz (Germany)

1995-09-01

35 patients with ankle sprain were examined by MRI and stress radiographs. 13 were operated afterwards, 22 patients underwent a functional conservative therapy and were examined by MRI and stress radiographs and second time after three months. MRI reports were correct in 12 of 13 operated cases. After conservative therapy we did not find any disrupted ankle ligament. MRI showed intact ligaments thickened by scar. (orig./MG) [Deutsch] 35 Patienten mit klinischem Verdacht auf Aussenbandruptur wurden mit der MRT untersucht. 13 Patienten wurden operiert, 22 konzervativ therapiert. Letztere wurden nach drei Monaten erneut mit MRT und gehaltenen Aufnahmen untersucht. Die MRT-Befunde stimmten in 12 von 13 Faellen mit den operativ erhobenen Befunden ueberein. Nach dreimonatiger konzervativer Therapie waren alle 22 Sprunggelenke stabil. Die rupturierten Baender stellten sich verdickt und durchgaengig dar. (orig./MG)

Trick or Treat and Telescopes

Science.gov (United States)

Buratti, Bonnie J.; Meinke, Bonnie K.; Schmude, Richard W.

2017-10-01

Based on an activity that DPS member Richard Schmude Jr. has been doing for years, with over 5000 children reached, DPS initiated in 2016 a pilot program entitled “Trick-or-Treat and Telescopes.” DPS encouraged its members to put out their telescopes during trick-or-treat time on Halloween, in their own lawns or in a neighbor’s lawn with better viewing (or more traffic). The program will be continued in 2017. This year should offer good viewing with a waxing gibbous moon and Saturn visible. The program was also advertised though the Night Sky Network, a consortium of astronomy clubs. The following website gives advice and connections to resources.https://dps.aas.org/education/trick-or-treat-and-telescopes acknowledged.

The micro turbine: the MIT example; La micro turbine: l'exemple du MIT

Energy Technology Data Exchange (ETDEWEB)

Ribaud, Y. [Office National d' Etudes et de Recherches Aerospatiales (ONERA-DEFA), 92 - Chatillon (France)

2001-10-01

The micro turbine study began a few years ago at the MIT, with the participation of specialists from different fields. The purpose is the development of a MEMS (micro electro mechanical systems) based, 1 cm in diameter, micro gas turbine. Potential applications are devoted to micro drone propulsion, electric power generation for portable power sources in order to replace heavy Lithium batteries, satellite motorization, the surface distributed power for boundary suction on plane wings. The manufacturing constraints at such small scales lead to 2-D extruded shapes. The physical constraints stem from viscous effects and from limitations given by 2-D geometry. The time scales are generally shorter than for conventional machines. Otherwise the material properties are better at such length scales. Transposition from conventional turbomachinery laws is no more applicable and new design methods must be established. The present paper highlights the project progress and the technology breakthroughs. (author)

A decade of cost-reduction in very large telescopes - The SST as prototype of special-purpose telescopes

Science.gov (United States)

Smith, Harlan J.

1989-10-01

Many design and technical innovations over the past ten or fifteen years have reduced the costs of very large telescopes by nearly an order of magnitude over those of classical designs. Still a further order of magnitude reduction is possible if the telescope is specialized for on-axis spectroscopy, giving up especially the luxuries of wide field, multiple focal positions, and access to all the sky at will. The SST (Spectroscopic Survey Telescope) will use eighty-five 1-m circular mirrors mounted in a steel frame composed of hundreds of interlocking tetrahedrons, keeping a fixed elevation angle of 60 deg with rotation only in azimuth. Using an optical fiber it will feed as much light to spectrographs as can be done by a conventional 8-m telescope, yet has a target basic completion cost of only $6 million.

The readout and control system of the mid-size telescope prototype of the Cherenkov telescope array

International Nuclear Information System (INIS)

Oya, I; Anguner, O; Birsin, E; Schwanke, U; Behera, B; Melkumyan, D; Schmidt, T; Sternberger, R; Wegner, P; Wiesand, S; Fuessling, M

2014-01-01

The Cherenkov Telescope Array (CTA) is one of the major ground-based astronomy projects being pursued and will be the largest facility for ground-based y-ray observations ever built. CTA will consist of two arrays: one in the Northern hemisphere composed of about 20 telescopes, and the other one in the Southern hemisphere composed of about 100 telescopes, both arrays containing telescopes of different type and size. A prototype for the Mid-Size Telescope (MST) with a diameter of 12 m has been installed in Berlin and is currently being commissioned. This prototype is composed of a mechanical structure, a drive system and mirror facets mounted with powered actuators to enable active control. Five Charge-Coupled Device (CCD) cameras, and a wide set of sensors allow the evaluation of the performance of the instrument. The design of the control software is following concepts and tools under evaluation within the CTA consortium in order to provide a realistic test-bed for the middleware: 1) The readout and control system for the MST prototype is implemented with the Atacama Large Millimeter/submillimeter Array (ALMA) Common Software (ACS) distributed control middleware; 2) the OPen Connectivity-Unified Architecture (OPC UA) is used for hardware access; 3) the document oriented MongoDB database is used for an efficient storage of CCD images, logging and alarm information: and 4) MySQL and MongoDB databases are used for archiving the slow control monitoring data and for storing the operation configuration parameters. In this contribution, the details of the implementation of the control system for the MST prototype telescope are described.

The readout and control system of the mid-size telescope prototype of the Cherenkov Telescope Array

Science.gov (United States)

Oya, I.; Anguner, O.; Behera, B.; Birsin, E.; Fuessling, M.; Melkumyan, D.; Schmidt, T.; Schwanke, U.; Sternberger, R.; Wegner, P.; Wiesand, S.; Cta Consortium,the

2014-06-01

The Cherenkov Telescope Array (CTA) is one of the major ground-based astronomy projects being pursued and will be the largest facility for ground-based y-ray observations ever built. CTA will consist of two arrays: one in the Northern hemisphere composed of about 20 telescopes, and the other one in the Southern hemisphere composed of about 100 telescopes, both arrays containing telescopes of different type and size. A prototype for the Mid-Size Telescope (MST) with a diameter of 12 m has been installed in Berlin and is currently being commissioned. This prototype is composed of a mechanical structure, a drive system and mirror facets mounted with powered actuators to enable active control. Five Charge-Coupled Device (CCD) cameras, and a wide set of sensors allow the evaluation of the performance of the instrument. The design of the control software is following concepts and tools under evaluation within the CTA consortium in order to provide a realistic test-bed for the middleware: 1) The readout and control system for the MST prototype is implemented with the Atacama Large Millimeter/submillimeter Array (ALMA) Common Software (ACS) distributed control middleware; 2) the OPen Connectivity-Unified Architecture (OPC UA) is used for hardware access; 3) the document oriented MongoDB database is used for an efficient storage of CCD images, logging and alarm information: and 4) MySQL and MongoDB databases are used for archiving the slow control monitoring data and for storing the operation configuration parameters. In this contribution, the details of the implementation of the control system for the MST prototype telescope are described.

Design and development of telescope control system and software for the 50/80 cm Schmidt telescope

Science.gov (United States)

Kumar, T. S.; Banavar, R. N.

2012-09-01

In this paper, we describe the details of telescope controller design for the 50/80 cm Schmidt telescope at the Aryabhatta Research Institute of observational sciencES. The GUI based software for commanding the telescope is developed in Visual C++. The hardware architecture features a distributed network of microcontrollers over CAN. The basic functionality can also be implemented using the dedicated RS232 port per board. The controller is able to perform with negligible rms velocity errors. At fine speeds limit cycles are exhibited due to nonlinear friction. At speeds over 3.90 × 10-02 radians/sec, the PI controller performs with peak errors less than 1%.

Simulation and track reconstruction for beam telescopes

CERN Document Server

Maqbool, Salman

2017-01-01

Beam telescopes are used for testing new detectors under development. Sensors are placed and a particle beam is passed through them. To test these novel detectors and determine their properties, the particle tracks need to be reconstructed from the known detectors in the telescope. Based on the reconstructed track, it’s predicted hits on the Device under Test (DUT) are compared with the actual hits on the DUT. Several methods exist for track reconstruction, but most of them don’t account for the effects of multiple scattering. General Broken Lines is one such algorithm which incorporates these effects during reconstruction. The aim of this project was to simulate the beam telescope and extend the track reconstruction framework for the FE-I4 telescope, which takes these effects into account. Section 1 introduces the problem, while section 2 focuses on beam telescopes. This is followed by the Allpix2 simulation framework in Section 3. And finally, Section 4 introduces the Proteus track reconstruction framew...

Habitable Exoplanet Imager Optical Telescope Concept Design

Science.gov (United States)

Stahl, H Philip

2017-01-01

The Habitable Exoplanet Imaging Mission (HabEx) is one of four missions under study for the 2020 Astrophysics Decadal Survey. Its goal is to directly image and spectroscopically characterize planetary systems in the habitable zone of Sun-like stars. Additionally, HabEx will perform a broad range of general astrophysics science enabled by 100 to 2500 nm spectral range and 3 x 3 arc-minute FOV. Critical to achieving the HabEx science goals is a large, ultra-stable UV/Optical/Near-IR (UVOIR) telescope. The baseline HabEx telescope is a 4-meter off-axis unobscured three-mirror-anastigmatic, diffraction limited at 400 nm with wavefront stability on the order of a few 10s of picometers. This paper summarizes the opto-mechanical design of the HabEx baseline optical telescope assembly, including a discussion of how science requirements drive the telescope's specifications, and presents analysis that the baseline telescope structure meets its specified tolerances.

Simulation and Track Reconstruction for Beam Telescopes

CERN Document Server

Maqbool, Salman

2017-01-01

Beam telescopes are an important tool to test new detectors under development in a particle beam. To test these novel detectors and determine their properties, the particle tracks need to be reconstructed from the known detectors in the telescope. Based on the reconstructed track, its predicted position on the Device under Test (DUT) are compared with the actual hits on the DUT. Several methods exist for track reconstruction, but most of them do not account for the effects of multiple scattering. General Broken Lines is one such algorithm which incorporates these effects during reconstruction. The aim of this project was to simulate the beam telescope and extend the track reconstruction framework for the FE-I4 telescope, which takes these effects into account. Section 1 introduces the problem, while section 2 focuses on beam telescopes. This is followed by the Allpix2 simulation framework in Section 3. And finally, Section 4 introduces the Proteus track reconstruction framework along with the General Broken ...

Habitable exoplanet imager optical telescope concept design

Science.gov (United States)

Stahl, H. Philip

2017-09-01

The Habitable Exoplanet Imaging Mission (HabEx) is one of four missions under study for the 2020 Astrophysics Decadal Survey. Its goal is to directly image and spectroscopically characterize planetary systems in the habitable zone of Sunlike stars. Additionally, HabEx will perform a broad range of general astrophysics science enabled by 100 to 2500 nm spectral range and 3 x 3 arc-minute FOV. Critical to achieving the HabEx science goals is a large, ultra-stable UV/Optical/Near-IR (UVOIR) telescope. The baseline HabEx telescope is a 4-meter off-axis unobscured three-mirroranastigmatic, diffraction limited at 400 nm with wavefront stability on the order of a few 10s of picometers. This paper summarizes the opto-mechanical design of the HabEx baseline optical telescope assembly, including a discussion of how science requirements drive the telescope's specifications, and presents analysis that the baseline telescope structure meets its specified tolerances.

Information and Communications Technology (ICT) Infrastructure for the ASTRI SST-2M telescope prototype for the Cherenkov Telescope Array

Science.gov (United States)

Gianotti, F.; Tacchini, A.; Leto, G.; Martinetti, E.; Bruno, P.; Bellassai, G.; Conforti, V.; Gallozzi, S.; Mastropietro, M.; Tanci, C.; Malaguti, G.; Trifoglio, M.

2016-08-01

The Cherenkov Telescope Array (CTA) represents the next generation of ground-based observatories for very high energy gamma-ray astronomy. The CTA will consist of two arrays at two different sites, one in the northern and one in the southern hemisphere. The current CTA design foresees, in the southern site, the installation of many tens of imaging atmospheric Cherenkov telescopes of three different classes, namely large, medium and small, so defined in relation to their mirror area; the northern hemisphere array would consist of few tens of the two larger telescope types. The Italian National Institute for Astrophysics (INAF) is developing the Cherenkov Small Size Telescope ASTRI SST- 2M end-to-end prototype telescope within the framework of the International Cherenkov Telescope Array (CTA) project. The ASTRI prototype has been installed at the INAF observing station located in Serra La Nave on Mt. Etna, Italy. Furthermore a mini-array, composed of nine of ASTRI telescopes, has been proposed to be installed at the Southern CTA site. Among the several different infrastructures belonging the ASTRI project, the Information and Communication Technology (ICT) equipment is dedicated to operations of computing and data storage, as well as the control of the entire telescope, and it is designed to achieve the maximum efficiency for all performance requirements. Thus a complete and stand-alone computer centre has been designed and implemented. The goal is to obtain optimal ICT equipment, with an adequate level of redundancy, that might be scaled up for the ASTRI mini-array, taking into account the necessary control, monitor and alarm system requirements. In this contribution we present the ICT equipment currently installed at the Serra La Nave observing station where the ASTRI SST-2M prototype will be operated. The computer centre and the control room are described with particular emphasis on the Local Area Network scheme, the computing and data storage system, and the

Die Behandlung des Akustikusneurinoms mit dem Gamma-Knife

OpenAIRE

Hempel, Elizabeta

2005-01-01

Das Akustikusneurinom ist mit ca. 6% der häufigste intrakranielle Tumor und hat eine jährliche Inzidenz von 1:100000. Die durchschnittliche Wachstumsrate beträgt 2 mm pro Jahr, wobei es auch Akustikusneurinome gibt, die sehr viel schneller wachsen können. Bei der Behandlung des Schwannoms stehen uns zwei Modalitäten zur Verfügung. Die konventionelle Chirurgie und die stereotaktische Radiochirurgie, zu der die Gamma-Knife Therapie und der Linearbeschleuniger zählen. Sorgfältig ausgesuchte P...

M1-transitions in the MIT bag model

International Nuclear Information System (INIS)

Hackman, R.H.; Deshpande, N.G.; Dicus, D.A.; Teplitz, V.L.

1977-03-01

In the MIT bag model, the M1-transitions of low lying hadrons are investigated. The following calculations are performed: 32 hadron masses are recomputed with a choice of bag parameters designed to give the correct values for the proton magnetic moment, μ/sub p/, and several masses, M/sub rho/ M/sub ω/ M/sub Δ/ M/sub Ω/, and M/sub D/; (2) eta, eta', eta/sub c/ mixing is computed in an untrustworthy approximation; and the widths for 38 M1-transitions are computed

Schlafmedizinische Charakterisierung von Parkinson-Patienten mit Schlafattacken unter dopaminerger Therapie

OpenAIRE

Rethfeldt, Mira

2006-01-01

1999 wurden erstmals sogenannte Schlafattacken bei Parkinson-Patienten unter der Therapie mit Nonergolin-Dopaminagonisten berichtet. Später zeigten Studien, dass diese Schlafattacken unter jeglicher dopaminerger Therapie auftreten können. Bis heute ist jedoch die Pathophysiologie dieses Phänomens nicht hinreichend geklärt. Es wird diskutiert, ob diese Attacken als paroxysmales Symptom überhaupt bestehen oder nicht vielmehr ...

Space Telescope maintenance and refurbishment

Science.gov (United States)

Trucks, H. F.

1983-01-01

The Space Telescope (ST) represents a new concept regarding spaceborne astronomical observatories. Maintenance crews will be brought to the orbital worksite to make repairs and replace scientific instruments. For major overhauls the telescope can be temporarily returned to earth with the aid of the Shuttle. It will, thus, be possible to conduct astronomical studies with the ST for two decades or more. The five first-generation scientific instruments used with the ST include a wide field/planetary camera, a faint object camera, a faint object spectrograph, a high resolution spectrograph, and a high speed photometer. Attention is given to the optical telescope assembly, the support systems module, aspects of mission and science operations, unscheduled maintenance, contingency orbital maintenance, planned on-orbit maintenance, ground maintenance, ground refurbishment, and ground logistics.

Eyes on the sky a spectrum of telescopes

CERN Document Server

Graham-Smith, Francis

2016-01-01

Astronomy is experiencing a golden age, with a new generation of innovative telescopes yielding a flood of information on the Universe. This book traces the development of telescopes from Galileo to the present day, and explains the basic principles of telescopes that operate in different parts of electromagnetic spectrum.

Optical Design for a Survey X-Ray Telescope

Science.gov (United States)

Saha, Timo T.; Zhang, William W.; McClelland, Ryan S.

2014-01-01

Optical design trades are underway at the Goddard Space Flight Center to define a telescope for an x-ray survey mission. Top-level science objectives of the mission include the study of x-ray transients, surveying and long-term monitoring of compact objects in nearby galaxies, as well as both deep and wide-field x-ray surveys. In this paper we consider Wolter, Wolter-Schwarzschild, and modified Wolter-Schwarzschild telescope designs as basic building blocks for the tightly nested survey telescope. Design principles and dominating aberrations of individual telescopes and nested telescopes are discussed and we compare the off-axis optical performance at 1.0 KeV and 4.0 KeV across a 1.0-degree full field-of-view.

Kundenorientierte Produktentwicklung mit Hilfe von Quality Function Deployment (QFD)

OpenAIRE

Schloske, Alexander

2011-01-01

Die Produktentwicklung von heute muss in immer kürzeren Zeiträumen kunden- und kostenorientierte Produkte entwickeln. Zur systematischen Unterstützung dieser Aufgabe im Rahmen der Produktentwicklung wird die Methode Quality Function Deployment (QFD) eingesetzt. Die konsequente Umsetzung der Stimme des Kunden in die Sprache des Unternehmens gelingt mit Quality Function Deployment (QFD). Die Methode wertet systematisch Kundenanforderungen an Produkte aus und führt zu innovativen Lösungen, die s...

MitBASE : a comprehensive and integrated mitochondrial DNA database. The present status

NARCIS (Netherlands)

Attimonelli, M.; Altamura, N.; Benne, R.; Brennicke, A.; Cooper, J. M.; D'Elia, D.; Montalvo, A.; Pinto, B.; de Robertis, M.; Golik, P.; Knoop, V.; Lanave, C.; Lazowska, J.; Licciulli, F.; Malladi, B. S.; Memeo, F.; Monnerot, M.; Pasimeni, R.; Pilbout, S.; Schapira, A. H.; Sloof, P.; Saccone, C.

2000-01-01

MitBASE is an integrated and comprehensive database of mitochondrial DNA data which collects, under a single interface, databases for Plant, Vertebrate, Invertebrate, Human, Protist and Fungal mtDNA and a Pilot database on nuclear genes involved in mitochondrial biogenesis in Saccharomyces

ANTARES : The first undersea neutrino telescope

NARCIS (Netherlands)

Ageron, M.; Aguilar, J. A.; Al Samarai, I.; Albert, A.; Ameli, F.; Andre, M.; Anghinolfi, M.; Anton, G.; Anvar, S.; Ardid, M.; Arnaud, K.; Aslanides, E.; Jesus, A. C. Assis; Astraatmadja, T.; Aubert, J. -J.; Auer, R.; Barbarito, E.; Baret, B.; Basa, S.; Bazzotti, M.; Becherini, Y.; Beltramelli, J.; Bersani, A.; Bertin, V.; Beurthey, S.; Biagi, S.; Bigongiari, C.; Billault, M.; Blaes, R.; Bogazzi, C.; de Botton, N.; Bou-Cabo, M.; Boudahef, B.; Bouwhuis, M. C.; Brown, A. M.; Brunner, J.; Busto, J.; Caillat, L.; Calzas, A.; Camarena, F.; Capone, A.; Caponetto, L.; Carloganu, C.; Carminati, G.; Carmona, E.; Carr, J.; Carton, P. H.; Cassano, B.; Castorina, E.; Cecchini, S.; Ceres, A.; Chaleil, Th; Charvis, Ph; Chauchot, P.; Chiarusi, T.; Circella, M.; Compere, C.; Coniglione, R.; Coppolani, X.; Cosquer, A.; Costantini, H.; Cottini, N.; Coyle, P.; Cuneo, S.; Curtil, C.; D'Amato, C.; Damy, G.; van Dantzig, R.; De Bonis, G.; Decock, G.; Decowski, M. P.; Dekeyser, I.; Delagnes, E.; Desages-Ardellier, F.; Deschamps, A.; Destelle, J. -J.; Di Maria, F.; Dinkespiler, B.; Distefano, C.; Dominique, J. -L.; Donzaud, C.; Dornic, D.; Dorosti, Q.; Drogou, J. -F.; Drouhin, D.; Druillole, F.; Durand, D.; Durand, R.; Eberl, T.; Emanuele, U.; Engelen, J. J.; Ernenwein, J. -P.; Escoffier, S.; Falchini, E.; Favard, S.; Fehr, F.; Feinstein, F.; Ferri, M.; Ferry, S.; Fiorello, C.; Flaminio, V.; Folger, F.; Fritsch, U.; Fuda, J. -L.; Galata, S.; Galeotti, S.; Gay, P.; Gensolen, F.; Giacomelli, G.; Gojak, C.; Gomez-Gonzalez, J. P.; Goret, Ph.; Graf, K.; Guillard, G.; Halladjian, G.; Hallewell, G.; van Haren, H.; Hartmann, B.; Heijboer, A. J.; Heine, E.; Hello, Y.; Henry, S.; Hernandez-Rey, J. J.; Herold, B.; Hoessl, J.; Hogenbirk, J.; Hsu, C. C.; Hubbard, J. R.; Jaquet, M.; Jaspers, M.; de Jong, M.; Jourde, D.; Kadler, M.; Kalantar-Nayestanaki, N.; Kalekin, O.; Kappes, A.; Karg, T.; Karkar, S.; Karolak, M.; Katz, U.; Keller, P.; Kestener, P.; Kok, E.; Kok, H.; Kooijman, P.; Kopper, C.; Kouchner, A.; Kretschmer, W.; Kruijer, A.; Kuch, S.; Kulikovskiy, V.; Lachartre, D.; Lafoux, H.; Lagier, P.; Lahmann, R.; Lahonde-Hamdoun, C.; Lamare, P.; Lambard, G.; Languillat, J-C; Larosa, G.; Lavalle, J.; Le Guen, Y.; Le Provost, H.; LeVanSuu, A.; Lefevre, D.; Legou, T.; Lelaizant, G.; Leveque, C.; Lim, G.; Lo Presti, D.; Loehner, H.; Loucatos, S.; Louis, F.; Lucarelli, F.; Lyashuk, V.; Magnier, P.; Mangano, S.; Marcel, A.; Marcelin, M.; Margiotta, A.; Martinez-Mora, J. A.; Masullo, R.; Mazeas, F.; Mazure, A.; Meli, A.; Melissas, M.; Migneco, E.; Mongelli, M.; Montaruli, T.; Morganti, M.; Moscoso, L.; Motz, H.; Musumeci, M.; Naumann, C.; Naumann-Godo, M.; Neff, M.; Niess, V.; Nooren, G. J. L.; Oberski, J. E. J.; Olivetto, C.; Palanque-Delabrouille, N.; Patioselitis, D.; Papaleo, R.; Pavalas, G. E.; Payet, K.; Payre, P.; Peek, H.; Petrovic, J.; Piattelli, P.; Picot-Clemente, N.; Picq, C.; Piret, Y.; Poinsignon, J.; Popa, V.; Pradier, T.; Presani, E.; Prono, G.; Racca, C.; Raia, G.; van Randwijk, J.; Real, D.; Reed, C.; Rethore, F.; Rewiersma, P.; Riccobene, G.; Richardt, C.; Richter, R.; Ricol, J. S.; Rigaud, V.; Roca, V.; Roensch, K.; Rolin, J. -F.; Rostovtsev, A.; Rottura, A.; Roux, J.; Rujoiu, M.; Ruppi, M.; Russo, G. V.; Salesa, F.; Salomon, K.; Sapienza, P.; Schmitt, F.; Schoeck, F.; Schuller, J. -P.; Schuessler, F.; Sciliberto, D.; Shanidze, R.; Shirokov, E.; Simeone, F.; Sottoriva, A.; Spies, A.; Spona, T.; Spurio, M.; Steijger, J. J. M.; Stolarczyk, Th; Streeb, K.; Sulak, L.; Taiuti, M.; Tamburini, C.; Tao, C.; Tasca, L.; Terreni, G.; Tezier, D.; Toscano, S.; Urbano, F.; Valdy, P.; Vallage, B.; Van Elewyck, V.; Vannoni, G.; Vecchi, M.; Venekamp, G.; Verlaat, B.; Vernin, P.; Virique, E.; de Vries, G.; Wijnker, G.; Wobbe, G.; de Wolf, E.; Yakovenko, Y.; Yepes, H.; Zaborov, D.; Zaccone, H.; Zornoza, J. D.; Zuniga, J.; van Wijk, R.

2011-01-01

The ANTARES Neutrino Telescope was completed in May 2008 and is the first operational Neutrino Telescope in the Mediterranean Sea. The main purpose of the detector is to perform neutrino astronomy and the apparatus also offers facilities for marine and Earth sciences. This paper describes the

Optimal networks of future gravitational-wave telescopes

Science.gov (United States)

Raffai, Péter; Gondán, László; Heng, Ik Siong; Kelecsényi, Nándor; Logue, Josh; Márka, Zsuzsa; Márka, Szabolcs

2013-08-01

We aim to find the optimal site locations for a hypothetical network of 1-3 triangular gravitational-wave telescopes. We define the following N-telescope figures of merit (FoMs) and construct three corresponding metrics: (a) capability of reconstructing the signal polarization; (b) accuracy in source localization; and (c) accuracy in reconstructing the parameters of a standard binary source. We also define a combined metric that takes into account the three FoMs with practically equal weight. After constructing a geomap of possible telescope sites, we give the optimal 2-telescope networks for the four FoMs separately in example cases where the location of the first telescope has been predetermined. We found that based on the combined metric, placing the first telescope to Australia provides the most options for optimal site selection when extending the network with a second instrument. We suggest geographical regions where a potential second and third telescope could be placed to get optimal network performance in terms of our FoMs. Additionally, we use a similar approach to find the optimal location and orientation for the proposed LIGO-India detector within a five-detector network with Advanced LIGO (Hanford), Advanced LIGO (Livingston), Advanced Virgo, and KAGRA. We found that the FoMs do not change greatly in sites within India, though the network can suffer a significant loss in reconstructing signal polarizations if the orientation angle of an L-shaped LIGO-India is not set to the optimal value of ˜58.2°( + k × 90°) (measured counterclockwise from East to the bisector of the arms).

TAF-4 is required for the life extension of isp-1, clk-1 and tpk-1 Mit mutants.

Science.gov (United States)

Khan, Maruf H; Ligon, Melissa; Hussey, Lauren R; Hufnal, Bryce; Farber, Robert; Munkácsy, Erin; Rodriguez, Amanda; Dillow, Andy; Kahlig, Erynn; Rea, Shane L

2013-10-01

While numerous life-extending manipulations have been discovered in the nematode Caenorhabditis elegans, one that remains most enigmatic is disruption of oxidative phosphorylation. In order to unravel how such an ostensibly deleterious manipulation can extend lifespan, we sought to identify the ensemble of nuclear transcription factors that are activated in response to defective mitochondrial electron transport chain (ETC) function. Using a feeding RNAi approach, we targeted over 400 transcription factors and identified 15 that, when reduced in function, reproducibly and differentially altered the development, stress response, and/or fecundity of isp-1(qm150) Mit mutants relative to wild-type animals. Seven of these transcription factors--AHA-1, CEH-18, HIF-1, JUN-1, NHR-27, NHR-49 and the CREB homolog-1 (CRH-1)-interacting protein TAF-4--were also essential for isp-1 life extension. When we tested the involvement of these seven transcription factors in the life extension of two other Mit mutants, namely clk-1(qm30) and tpk-1(qm162), TAF-4 and HIF-1 were consistently required. Our findings suggest that the Mit phenotype is under the control of multiple transcriptional responses, and that TAF-4 and HIF-1 may be part of a general signaling axis that specifies Mit mutant life extension.

Active control of the Chinese Giant Solar Telescope

Science.gov (United States)

Dai, Yichun; Yang, Dehua; Jin, Zhenyu; Liu, Zhong; Qin, Wei

2014-07-01

The Chinese Giant Solar Telescope (CGST) is the next generation solar telescope of China with diameter of 8 meter. The unique feature of CGST is that its primary is a ring, which facilitates the polarization detection and thermal control. In its present design and development phase, two primary mirror patterns are considered. For one thing, the primary mirror is expected to construct with mosaic mirror with 24 trapezoidal (or petal) segments, for another thing, a monolithic mirror is also a candidate for its primary mirror. Both of them depend on active control technique to maintain the optical quality of the ring mirror. As a solar telescope, the working conditions of the CGST are quite different from those of the stellar telescopes. To avoid the image deterioration due to the mirror seeing and dome seeing, especially in the case of the concentration of flux in a solar telescope, large aperture solar projects prefer to adopt open telescopes and open domes. In this circumstance, higher wind loads act on the primary mirror directly, which will cause position errors and figure errors of the primary with matters worse than those of the current 10-meter stellar telescopes with dome protect. Therefore, it gives new challenges to the active control capability, telescope structure design, and wind shielding design. In this paper, the study progress of active control of CGST for its mosaic and monolithic mirror are presented, and the wind effects on such two primary mirrors are also investigated.

Hardware for quasi-single-shot multifrequency magnetic induction tomography (MIT): the Graz Mk2 system

International Nuclear Information System (INIS)

Scharfetter, H; Köstinger, A; Issa, S

2008-01-01

Magnetic induction tomography (MIT) has been suggested by several groups for the contact-less mapping of the passive electrical properties of tissues via AC magnetic fields in the frequency range between several tens of kHz and several tens of MHz. Multifrequency MIT as an analog to multifrequency EIT has been tried and first image reconstructions have been demonstrated with phantoms. MIT appears to yield comparable images to EIT but offers the advantage of being non-contacting. In the beta-dispersion range of most tissues the method is challenging because the signals are very small and buried in noise. In order to minimize drifts and systematic errors fast data acquisition is therefore pivotal. This paper presents a method for single-shot MIT which allows us to acquire the data for a multifrequency image with an analog bandwidth of 50 kHz–1.5 MHz which covers a good part of the β-dispersion of many tissues. The transmit (TX) coils are simultaneously driven by individual power amplifiers with a multisinus pattern with up to 3 A pp . The amplifiers are configured as current sources so as not to perturb the excitation fields by inappropriately terminated coils. The separation of the different TX channels after reception is achieved by splitting up the carrier frequencies into individual subcarriers with a narrow spacing of at most 300 Hz. In this way every TX coil is identifiable by its own subcarrier but the whole excitation band is contained within a few kHz. The real and imaginary parts of the received signals are extracted efficiently with FFT. The system noise and the sources for low-frequency perturbations are analyzed and characterized

Plattenepithelkarzinom in Verbindung mit einer roten Tätowierung.

Science.gov (United States)

Schmitz, Inge; Prymak, Oleg; Epple, Matthias; Ernert, Carsten; Tannapfel, Andrea

2016-06-01

Obwohl Tätowierungen in den letzten Jahren außerordentlich beliebt geworden sind, wurde in der Literatur bisher nur über wenige Fälle schwerer Reaktionen berichtet, die zu einer malignen Transformation führten. Dies steht im Kontrast zu der praktisch unüberschaubaren Zahl an Tätowierungen weltweit. Die Zusammensetzung der für Tätowierungen verwendeten Farbstoffe variiert stark, und selbst gleiche Farbtöne können unterschiedliche Komponenten enthalten. Das Ziel unserer Studie war es zu untersuchen, auf welche Weise Tätowierungen möglicherweise Hautkrebs auslösen können. Wir berichten über den seltenen Fall einer 24-jährigen Frau, bei der sich sieben Monate nachdem sie eine Tätowierung auf dem Fußrücken erhalten hatte in unmittelbarer Nähe des verwendeten roten Farbstoffs ein Plattenepithelkarzinom entwickelte. Die Komplikationen begannen mit einer unspezifischen Schwellung. Die Läsion wurde histologisch untersucht. Die Zusammensetzung des inkorporierten Farbstoffs wurde mittels Rasterelektronenmikroskopie in Kombination mit energiedispersiver Elementanalyse analysiert. Zur weiteren Charakterisierung wurden Thermogravimetrie und Pulverdiffraktometrie eingesetzt. Der Tätowierungsfarbstoff enthielt hauptsächlich Bariumsulfat; Spuren von Al, S, Ti, P, Mg und Cl ließen sich ebenfalls nachweisen. Bei der Analyse zeigten sich Pigmentgranula unterschiedlicher Größe. In seltenen Fällen kann Tätowierungstinte karzinogene Effekte haben, die multifaktoriell zu sein scheinen. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

EUSO-TA prototype telescope

Energy Technology Data Exchange (ETDEWEB)

Bisconti, Francesca, E-mail: francesca.bisconti@kit.edu

2016-07-11

EUSO-TA is one of the prototypes developed for the JEM-EUSO project, a space-based large field-of-view telescope to observe the fluorescence light emitted by cosmic ray air showers in the atmosphere. EUSO-TA is a ground-based prototype located at the Telescope Array (TA) site in Utah, USA, where an Electron Light Source and a Central Laser Facility are installed. The purpose of the EUSO-TA project is to calibrate the prototype with the TA fluorescence detector in presence of well-known light sources and cosmic ray air showers. In 2015, the detector started the first measurements and tests using the mentioned light sources have been performed successfully. A first cosmic ray candidate has been observed, as well as stars of different magnitude and color index. Since Silicon Photo-Multipliers (SiPMs) are very promising for fluorescence telescopes of next generation, they are under consideration for the realization of a new prototype of EUSO Photo Detector Module (PDM). The response of this sensor type is under investigation through simulations and laboratory experimentation.

EUSO-TA prototype telescope

Science.gov (United States)

Bisconti, Francesca; JEM-EUSO Collaboration

2016-07-01

EUSO-TA is one of the prototypes developed for the JEM-EUSO project, a space-based large field-of-view telescope to observe the fluorescence light emitted by cosmic ray air showers in the atmosphere. EUSO-TA is a ground-based prototype located at the Telescope Array (TA) site in Utah, USA, where an Electron Light Source and a Central Laser Facility are installed. The purpose of the EUSO-TA project is to calibrate the prototype with the TA fluorescence detector in presence of well-known light sources and cosmic ray air showers. In 2015, the detector started the first measurements and tests using the mentioned light sources have been performed successfully. A first cosmic ray candidate has been observed, as well as stars of different magnitude and color index. Since Silicon Photo-Multipliers (SiPMs) are very promising for fluorescence telescopes of next generation, they are under consideration for the realization of a new prototype of EUSO Photo Detector Module (PDM). The response of this sensor type is under investigation through simulations and laboratory experimentation.

Entwicklung und Anwendung neuer NMR-Methoden: Orientierungsmedien zur Strukturbestimmung mit anisotropen Parametern und Metabonomics

OpenAIRE

Büchler, Silke

2014-01-01

Das Ziel dieser Arbeit war die Entwicklung und Anwendung neuer Orientierungsmedien zur Strukturbestimmung mit anisotropen Parametern, sowie die Etablierung von Metabonomics-Studien an Flüssigzellkulturen und Reispflanzen.

Development of the quality control system of the readout electronics for the large size telescope of the Cherenkov Telescope Array observatory

Science.gov (United States)

Konno, Y.; Kubo, H.; Masuda, S.; Paoletti, R.; Poulios, S.; Rugliancich, A.; Saito, T.

2016-07-01

The Cherenkov Telescope Array (CTA) is the next generation VHE γ-ray observatory which will improve the currently available sensitivity by a factor of 10 in the range 100 GeV to 10 TeV. The array consists of different types of telescopes, called large size telescope (LST), medium size telescope (MST) and small size telescope (SST). A LST prototype is currently being built and will be installed at the Observatorio Roque de los Muchachos, island of La Palma, Canary islands, Spain. The readout system for the LST prototype has been designed and around 300 readout boards will be produced in the coming months. In this note we describe an automated quality control system able to measure basic performance parameters and quickly identify faulty boards.

Mathematical modelling of the performance of hydrodynamic couplings using hybrid models; Mathematische Modellierung des Betriebsverhaltens hydrodynamischer Kupplungen mit hybriden Modellansaetzen

Energy Technology Data Exchange (ETDEWEB)

Jaschke, P.

2000-02-01

Mathematical models of the dynamic performance of hydrodynamic couplings are developed using hybrid modelling, i.e. a combination of analytical physical modelling and black box identification. The models developed were verified by measurements on a model powertrain. [German] In dieser Arbeit werden mit Hilfe der hybriden Modellierung mathematische Modelle zur Beschreibung des dynamischen Betriebsverhaltens hydrodynamischer Kupplungen ermittelt. Die Hybride Modellierung stellt eine Kombination der analytisch physikalischen Modellierung und der Black-Box-Identifikation dar. Diese Modellierungsart ist ausgewaehlt worden, um die Vorteile der analytisch physikalischen Modellierung und der Black-Box-Identifikation hydrodynamischer Kupplungen zu verbinden und deren Nachteile gering zu halten. Auf dieser Basis ist eine Vorgehensweise vorgestellt worden, die die Ermittlung der Modelle mit wenig Aufwand ermoeglicht. Mit Hilfe der Modelltheorie wird gezeigt, wie die ermittelten mathematischen Modelle zur Simulation des dynamischen Betriebsverhaltens geometrisch aehnlicher Kupplungen unterschiedlicher Baugroessen verwendet werden koennen. Darueber hinaus wird dargelegt, wie die ermittelten Modelle mit Modellen anderer Antriebsstrangelemente gekoppelt werden koennen, um Antriebsstrangsimulationen zu ermoeglichen. Verifikationsmessungen an einem Modellantriebsstrang verdeutlichen die Guete und Verwendbarkeit der mathematischen Modelle. (orig.)

Flippige Online-PDFs - Webpublikationen mit Umblätter-Effekt durch das MegaZine3-Tool

Directory of Open Access Journals (Sweden)

Klaudia Mattern

2013-03-01

Full Text Available Webdokumente werden in letzter Zeit immer häufiger mit einem Umblätter–Effekt präsentiert. Beliebt ist dies vor allem für Onlineversionen von Printmagazinen, Produktkatalogen und die Postwurfflyer von Super- und Baumärkten. Diese Funktion des Umblätterns wird mit diversen Begriffen Flip Book, Pageflip, … bezeichnet – einige davon sind markenrechtlich geschützt – was es echt schwierig macht, sich googelnder Weise einen raschen Überblick zu solchen Tools zu verschaffen. Wer es dennoch schafft, findet schnell heraus, dass diese Funktion eher im professionellen, hochpreisigen Desktop- und Online-Publishing Bereich angesiedelt ist. Für medienpädagogisch motivierte Projektergebnisse gibt’s wenig Optionen[FN1], die die Eigenverantwortung bei der Onlinepublikation und Onlineverbreitung unterstützen. Daher war ich sehr erfreut, als ich mit MegaZine3 (MZ3 ein Tool gefunden hab, dass einerseits als Basisversion für alle NutzerInnen kostenlos ist (nichteinmal registrierungspflichtig, für Schulen und Unis eine kostenlose EDU–Lizenz ermöglicht (unbegrenzte Seitenanzahl bei Registrierung der Schule und es MZ3 auch als deutschsprachige Version gibt, weil die Entwicklungsfirma in München zu hause ist.

Current activities at the MIT Research Reactor

International Nuclear Information System (INIS)

Hu Linwen; Bernard, John A.; Harling, Otto K.; Kohse, Gordon E.; Ames, Michael; Olmez, Ilhan

1998-01-01

The MIT Research Reactor (MITR) is a MW nuclear research reactor that is owned and operated by the Massachusetts Institute of Technology to further its educational and research goals at both the undergraduate and graduate level. The reactor first achieved criticality in 1958. It was largely rebuilt in 1973/1974 by MIT staff and students, and its current license expires in August 1999. The current facility, which is designated as the MITR-H, uses a compact core with finned, aluminum-clad, plate-type fuel that is cooled and moderated by light water and reflected by heavy water. The reactor core can hold twenty-seven fuel elements. However, the normal configuration is twenty-four elements. A maximum of four fuel elements can be replaced with in-core experimental facilities. A unique feature of the MITR-II's design is that fixed absorber plates can be inserted in the upper half of the core. These cause the flux to peak in the lower half which benefits experimenters and also facilitates a fuel strategy that involves inversion of fuel elements midway through their life cycle. The MITR-II currently operates continuously for four weeks followed by shutdown of a few days for maintenance. This paper provides an overview of current activities at the MITR including preparations for re-licensing. The status of an on-going Phase-I clinical trial of boron neutron capture therapy for both glioblastoma multiforme and metastatic melanoma is described as well as the design of a fission converter facility for BNCT. Environmental research using neutron activation analysis is summarized as well as in-pile research focussed on LWR water chemistry and structural materials. (author)

Teaching ``The Physics of Energy'' at MIT

Science.gov (United States)

Jaffe, Robert

2009-05-01

New physics courses on energy are popping up at colleges and universities across the country. Many require little or no previous physics background, aiming to introduce a broad audience to this complex and critical problem, often augmenting the scientific message with economic and policy discussions. Others are advanced courses, focussing on highly specialized subjects like solar voltaics, nuclear physics, or thermal fluids, for example. About two years ago Washington Taylor and I undertook to develop a course on the ``Physics of Energy'' open to all MIT students who had taken MIT's common core of university level calculus, physics, and chemistry. By avoiding higher level prerequisites, we aimed to attract and make the subject relevant to students in the life sciences, economics, etc. --- as well as physical scientists and engineers --- who want to approach energy issues in a sophisticated and analytical fashion, exploiting their background in calculus, mechanics, and E & M, but without having to take advanced courses in thermodynamics, quantum mechanics, or nuclear physics beforehand. Our object was to interweave teaching the fundamental physics principles at the foundations of energy science with the applications of those principles to energy systems. We envisioned a course that would present the basics of statistical, quantum, and fluid mechanics at a fairly sophisticated level and apply those concepts to the study of energy sources, conversion, transport, losses, storage, conservation, and end use. In the end we developed almost all of the material for the course from scratch. The course debuted this past fall. I will describe what we learned and what general lessons our experience might have for others who contemplate teaching energy physics broadly to a technically sophisticated audience.

EDUCATIONAL ASTRONOMICAL OBSERVATIONS ON REMOTE ACCESS TELESCOPES

Directory of Open Access Journals (Sweden)

Ivan P. Kriachko

2016-01-01

Full Text Available The purpose of this article is to show the way of overcoming one of the major problems of astronomy teaching methods in upper secondary school – organization of educational astronomical observations. Nowadays it became possible to perform such observations on remote access telescopes. By using up-to-date informational and communicational technologies, having an opportunity to work with robotic telescopes allows us to organize a unique cognitive and research oriented activities for students while conducting their specialized astronomical studies. Below here is given a brief description of the most significant robotic telescopes and the way of the usage of open remote access telescopic network which was created by professors and scientists of Harvard-Smithsonian Center for Astrophysics, USA.

Design of a propeller turbine with a variable revolution number; Entwicklung einer Propellerturbine mit variabler Drehzahl

Energy Technology Data Exchange (ETDEWEB)

Fella, G.; Wierer, C. [Fella GmbH Maschinen- und Apparatebau, Amorbach (Germany); Goede, E.; Batrekhy, S.; Ruprecht, A. [Stuttgart Univ. (Germany). Inst. fuer Stroemungsmechanik und Hydraulische Stroemungsmaschinen

1997-12-31

The small hydroelectric power station of Rupboden in the Oberfranken district was reactivated after having been decommissioned for 30 years. This new low pressure plant consists of an open-flume turbine with an adjustable diffusor and a firm rotor disk (propeller) with a vertical rod. A large range of operation at a constant height of fall is ensured by a variable revolution number. The profiles of the adjustable diffusor and rotor disk and the design of the draft tube were optimized using numerical flow calculation. First operating experience is very positive. The turbine runs extremely smoothly over the entire range. (orig.) [Deutsch] Das Kleinwasserkraftwerk Rupboden in Oberfanken wurde nach 30 Jahren Stillstand reaktiviert. Die neue Niederdruckanlage besteht aus einer Schachtturbine mit verstellbarem Leitapparat, feststehendem Laufrad (Propeller) mit senkrechter Welle. Zum Erzielen eines grossen Betriebsbereiches bei gleichbleibender Fallhoehe wurde eine variable Drehzahl vorgesehen. Die Profilierung von Leitapparat und Laufrad sowie die Formgebung fuer das Saugrohr wurden mit numerischer Stroemungsberechnung optimiert. Erste Betriebserfahrungen sind sehr positiv. Die Turbine laeuft im gesamten Leistungsbereich ausserordentlich ruhig. (orig.)

Development of a SiPM Camera for a Schwarzschild-Couder Cherenkov Telescope for the Cherenkov Telescope Array

CERN Document Server

Otte, A N; Dickinson, H.; Funk, S.; Jogler, T.; Johnson, C.A.; Karn, P.; Meagher, K.; Naoya, H.; Nguyen, T.; Okumura, A.; Santander, M.; Sapozhnikov, L.; Stier, A.; Tajima, H.; Tibaldo, L.; Vandenbroucke, J.; Wakely, S.; Weinstein, A.; Williams, D.A.

2015-01-01

We present the development of a novel 11328 pixel silicon photomultiplier (SiPM) camera for use with a ground-based Cherenkov telescope with Schwarzschild-Couder optics as a possible medium-sized telescope for the Cherenkov Telescope Array (CTA). The finely pixelated camera samples air-shower images with more than twice the optical resolution of cameras that are used in current Cherenkov telescopes. Advantages of the higher resolution will be a better event reconstruction yielding improved background suppression and angular resolution of the reconstructed gamma-ray events, which is crucial in morphology studies of, for example, Galactic particle accelerators and the search for gamma-ray halos around extragalactic sources. Packing such a large number of pixels into an area of only half a square meter and having a fast readout directly attached to the back of the sensors is a challenging task. For the prototype camera development, SiPMs from Hamamatsu with through silicon via (TSV) technology are used. We give ...

The Falcon Telescope Network

Science.gov (United States)

Chun, F.; Tippets, R.; Dearborn, M.; Gresham, K.; Freckleton, R.; Douglas, M.

2014-09-01

The Falcon Telescope Network (FTN) is a global network of small aperture telescopes developed by the Center for Space Situational Awareness Research in the Department of Physics at the United States Air Force Academy (USAFA). Consisting of commercially available equipment, the FTN is a collaborative effort between USAFA and other educational institutions ranging from two- and four-year colleges to major research universities. USAFA provides the equipment (e.g. telescope, mount, camera, filter wheel, dome, weather station, computers and storage devices) while the educational partners provide the building and infrastructure to support an observatory. The user base includes USAFA along with K-12 and higher education faculty and students. Since the FTN has a general use purpose, objects of interest include satellites, astronomical research, and STEM support images. The raw imagery, all in the public domain, will be accessible to FTN partners and will be archived at USAFA in the Cadet Space Operations Center. FTN users will be able to submit observational requests via a web interface. The requests will then be prioritized based on the type of user, the object of interest, and a user-defined priority. A network wide schedule will be developed every 24 hours and each FTN site will autonomously execute its portion of the schedule. After an observational request is completed, the FTN user will receive notification of collection and a link to the data. The Falcon Telescope Network is an ambitious endeavor, but demonstrates the cooperation that can be achieved by multiple educational institutions.

Review of 'Where the action is, by Paul Dorish, MIT Press 2001

DEFF Research Database (Denmark)

Wentzer, Helle

2008-01-01

Bogen til human-computer interaction, HCI er ikke helt ny (MIT 2001/2004), men dog filosofisk aktuel som baggrund for nye tanker, forventninger og krav til sundhedsinformatikken. Den foranker forskningprogrammerne til ’tangible computing’ og ’social computing’ paradigmatisk i fænomenologien og...

Content Management von Leittexten mit XML Topic Maps

Directory of Open Access Journals (Sweden)

Johannes Busse

2003-07-01

Full Text Available Die Autoren definieren den Umgang mit internet- basierten Informations- und Kommunikationstechnologien als Schlüsselqualifikation für Studierende aller Fachrichtungen. Im vorliegenden Aufsatz beschreiben sie ein Projekt, das der Fachbereich Erziehungswissenschaften der Universität Heidelberg seit 2001 durchführt. Hier werden Studierende der Geistes- und Sozialwissenschaften zu "Lernberatern" ausgebildet, die als Multiplikatoren die notwendigen Kenntnisse erwerben. Die Teilnehmenden erarbeiten nach der "Leittextmethode" selbstgesteuert xml-basierte Contents. Dies setzt den Erwerb von informationstechnischen Kenntnissen voraus, der neben dem Aufbau eines (sowohl technischen als auch sozialen Netzwerks einen Schwerpunkt bildet.

Processing of data from innovative parabolic strip telescope.

Science.gov (United States)

Kosejk, Vladislav; Novy, J.; Chadzitaskos, Goce

2015-12-01

This paper presents an innovative telescope design based on the usage of a parabolic strip fulfilling the function of an objective. Isaac Newton was the first to solve the problem of chromatic aberration, which is caused by a difference in the refractive index of lenses. This problem was solved by a new kind of telescope with a mirror used as an objective. There are many different kinds of telescopes. The most basic one is the lens telescope. This type of a telescope uses a set of lenses. Another type is the mirror telescope, which employs the concave mirror, spherical parabolic mirror or hyperbolically shaped mirror as its objective. The lens speed depends directly on the surface of a mirror. Both types can be combined to form a telescope composed of at least two mirrors and a set of lenses. The light is reflected from the primary mirror to the secondary one and then to the lens system. This type is smaller-sized, with a respectively reduced lens speed. The telescope design presented in this paper uses a parabolic strip fulfilling the function of an objective. Observed objects are projected as lines in a picture plane. Each of the lines of a size equal to the size of the strip corresponds to the sum of intensities of the light coming perpendicular to the objective from an observed object. A series of pictures taken with a different rotation and processed by a special reconstruction algorithm is needed to get 2D pictures. The telescope can also be used for fast detection of objects. In this mode, the rotation and multiple pictures are not needed, just one picture in the focus of a mirror is required to be taken.

Search for solar axions with the X-ray telescope of the CAST experiment (phase II); Suche nach solaren Axionen mit dem Roentgenteleskop des CAST-Experiments (Phase II)

Energy Technology Data Exchange (ETDEWEB)

Nordt, Annika

2009-10-14

The CAST (CERN Solar Axion Telescope) experiment is searching for solar axions by their conversion into photons inside a transverse magnetic field. So far, no solar axionsignal has been detected, but a new upper limit could be given (CAST Phase I). Since 2005, CAST entered in its second phase where it operates with a buffer gas ({sup 4}He) in the conversion region to extend the sensitivity of the experiment to higher axionmasses. For the first time it is possible to enter the theoretically favored axion massrange and to give an upper limit for this solar axion mass-range (>0.02 eV). This thesis is about the analysis of the X-ray telescope data Phase II with {sup 4}He inside the magnet. The result for the coupling constant of axions to photons is: g{sub {alpha}}{sub {gamma}}{sub {gamma}}<1.6-6.0 x 10{sup -10} GeV{sup -1} (95%C.L.) for m{sub a}=0.02-0.4 eV. (2) This result is better than any result that has been given before in this mass range for solar axions. (orig.)

Eddy current testing with high penetration; WS-Pruefungen mit grosser Eindringtiefe

Energy Technology Data Exchange (ETDEWEB)

Becker, R.; Kroening, M. [Fraunhofer Inst. fuer Zerstoerungsfreie Pruefverfahren, Saarbruecken (Germany)

1999-08-01

The low-frequency eddy current testing method is used when penetration into very deep layers is required. The achievable penetration depth is determined among other parameters by the lowest testing frequency that can be realised together with the eddy current sensor. When using inductive sensors, the measuring effect declines proportional to the lowering frequency (induction effect). Further reduction of testing frequency requires other types of sensors, as e.g. the GMR (Giant Magnetic Resistance), which achieves a constant measuring sensitivity down to the steady field. The multi-frequency eddy current testing method MFEC 3 of IZFP described here can be operated using three different scanning frequencies at a time. Two variants of eddy current probes are used in this case. Both have an inductive winding at their emitters, of the type of a measuring probe. The receiver end is either also an inductive winding, or a magnetic field-responsive resistance (GMR). (orig./CB) [Deutsch] Das Niederfrequenz(NF)-Wirbelstrom(WS)-Verfahren wird eingesetzt, um eine grosse Eindringtiefe zu erzielen. Die erreichbare Tiefenreichweite wird u.a. durch die niedrigste Prueffrequenz bestimmt, die zusammen mit dem Wirbelstrom-Sensor realisiert werden kann. Bei Einsatz von induktiven Sensoren geht mit abnehmender Prueffrequenz der Messeffekt proportional zurueck (Induktionswirkung). Eine weitere Absenkung der Prueffrequenzen macht den Einsatz von andersartigen Sensoren notwendig, z.B. den GMR (Giant Magnetic Resistance), der eine gleichmaessige Messempfindlichkeit bis zum Gleichfeld besitzt. Das eingesetzte Mehrfrequenz-Wirbelstrom-Pruefverfahren MFEC 3 des IZFP arbeitet mit drei gleichzeitig eingespeisten Prueffrequenzen. Dabei werden zwei Varianten von WS-Sensoren eingesetzt. Beide besitzen auf der Senderseite eine induktive Wicklung in der Art einer Tastsonde. Die Empfaengerseite ist entweder ebenfalls eine induktive Wicklung oder ein magnetfeldempfindlicher Widerstand (GMR). (orig./DGE)

Analyse der pharmazeutischen Versorgungssituation von Patienten mit Psoriasis-Arthritis auf Basis von Routinedaten der Gesetzlichen Krankenversicherung.

Science.gov (United States)

Sondermann, Wiebke; Ventzke, Julia; Matusiewicz, David; Körber, Andreas

2018-03-01

Die Psoriasis-Arthritis (PsA) gehört zu den chronisch entzündlichen Gelenkerkrankungen. Trotz zahlreicher versorgungswissenschaftlicher Studien in Deutschland liegen zur pharmazeutischen Versorgungssituation von PsA-Patienten bisher kaum aktuelle Ergebnisse vor. Mit Hilfe einer systematischen Literaturrecherche sowie anhand von Routinedaten der Allgemeinen Ortskrankenkasse (AOK) Rheinland/Hamburg wird ein aktueller Überblick über die pharmazeutische Versorgung von PsA-Patienten in Deutschland gegeben. Selektiert wurden Versicherte aus dem ambulanten und stationären Bereich, die im 1. und 2. Quartal des Jahres 2014 die gesicherte Abrechnungsdiagnose Psoriasis-Arthritis L40.5+ aufwiesen. Anschließend wurden auf Basis dieser "vorab definierten" Kohorte die Arzneimitteldaten für 5 Jahre (01.01.2010-31.12.2014) abgerufen. Es konnten insgesamt n  =  3205 Versicherte (45 % männlich, 55 % weiblich) der AOK Rheinland/Hamburg mit einer gesicherten PsA-Diagnose selektiert werden. Das Durchschnittsalter betrug 58,9 Jahre. 53,7 % der PsA-Patienten wurden mit systemischen PsA-relevanten Arzneimitteln versorgt. Nichtsteroidale Antirheumatika (NSAR) wurden am häufigsten verordnet, gefolgt von systemischen Glucocorticoiden. Von den selektierten PsA-Patienten, die eine Systemtherapie erhielten, wurden 72,1 % mittels einer Disease-modifying-antirheumatic-Drug (DMARD)-Monotherapie behandelt, gefolgt von der Kombinationstherapie aus DMARDs und Biologika (20,9 %). Die pharmakologische Therapie der PsA muss eine Gewährleistung zwischen adäquater Versorgung der PsA mit Verhinderung der Krankheitsprogression und ökonomischer Verantwortung darstellen. © 2018 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

Optimal networks of future gravitational-wave telescopes

International Nuclear Information System (INIS)

Raffai, Péter; Márka, Zsuzsa; Márka, Szabolcs; Gondán, László; Kelecsényi, Nándor; Heng, Ik Siong; Logue, Josh

2013-01-01

We aim to find the optimal site locations for a hypothetical network of 1–3 triangular gravitational-wave telescopes. We define the following N-telescope figures of merit (FoMs) and construct three corresponding metrics: (a) capability of reconstructing the signal polarization; (b) accuracy in source localization; and (c) accuracy in reconstructing the parameters of a standard binary source. We also define a combined metric that takes into account the three FoMs with practically equal weight. After constructing a geomap of possible telescope sites, we give the optimal 2-telescope networks for the four FoMs separately in example cases where the location of the first telescope has been predetermined. We found that based on the combined metric, placing the first telescope to Australia provides the most options for optimal site selection when extending the network with a second instrument. We suggest geographical regions where a potential second and third telescope could be placed to get optimal network performance in terms of our FoMs. Additionally, we use a similar approach to find the optimal location and orientation for the proposed LIGO-India detector within a five-detector network with Advanced LIGO (Hanford), Advanced LIGO (Livingston), Advanced Virgo, and KAGRA. We found that the FoMs do not change greatly in sites within India, though the network can suffer a significant loss in reconstructing signal polarizations if the orientation angle of an L-shaped LIGO-India is not set to the optimal value of ∼58.2°( + k × 90°) (measured counterclockwise from East to the bisector of the arms). (paper)

Quark matter revisited with non-extensive MIT bag model

Energy Technology Data Exchange (ETDEWEB)

Cardoso, Pedro H.G.; Nunes da Silva, Tiago; Menezes, Debora P. [Universidade Federal de Santa Catarina, Departamento de Fisica, CFM, Florianopolis (Brazil); Deppman, Airton [Instituto de Fisica da Universidade de Sao Paulo, Sao Paulo (Brazil)

2017-10-15

In this work we revisit the MIT bag model to describe quark matter within both the usual Fermi-Dirac and the Tsallis statistics. We verify the effects of the non-additivity of the latter by analysing two different pictures: the first order phase transition of the QCD phase diagram and stellar matter properties. While the QCD phase diagram is visually affected by the Tsallis statistics, the resulting effects on quark star macroscopic properties are barely noticed. (orig.)

Configuration management plan for Machine Interface Test System (MITS)

International Nuclear Information System (INIS)

O'Neill, C.K.

1980-01-01

The discipline required by this plan will apply from the establishment of a configuration baseline until completion of the final test in the MITS. The plan applies to configured items of hardware and software as well as to the specifications and drawings for these items. The plan encompasses establishment of the facility baseline, interface definition, classes of change, change control, change paper, organizational responsibilities and relationships, test configuration (as opposed to facility), and configuration data retention

Hubble Space Telescope: The Telescope, the Observations & the Servicing Mission

Science.gov (United States)

1999-11-01

Today the HST Archives contain more than 260 000 astronomical observations. More than 13 000 astronomical objects have been observed by hundreds of different groups of scientists. Direct proof of the scientific significance of this project is the record-breaking number of papers published : over 2400 to date. Some of HST's most memorable achievements are: * the discovery of myriads of very faint galaxies in the early Universe, * unprecedented, accurate measurements of distances to the farthest galaxies, * significant improvement in the determination of the Hubble constant and thus the age of the Universe, * confirmation of the existence of blacks holes, * a far better understanding of the birth, life and death of stars, * a very detailed look at the secrets of the process by which planets are created. Europe and HST ESA's contribution to HST represents a nominal investment of 15%. ESA provided one of the two imaging instruments - the Faint Object Camera (FOC) - and the solar panels. It also has 15 scientists and computer staff working at the Space Telescope Science Institute in Baltimore (Maryland). In Europe the astronomical community receives observational assistance from the Space Telescope European Coordinating Facility (ST-ECF) located in Garching, Munich. In return for ESA's investment, European astronomers have access to approximately 15% of the observing time. In reality the actual observing time competitively allocated to European astronomers is closer to 20%. Looking back at almost ten years of operation, the head of ST-ECF, European HST Project Scientist Piero Benvenuti states: "Hubble has been of paramount importance to European astronomy, much more than the mere 20% of observing time. It has given the opportunity for European scientists to use a top class instrument that Europe alone would not be able to build and operate. In specific areas of research they have now, mainly due to HST, achieved international leadership." One of the major reasons for

Development of the quality control system of the readout electronics for the large size telescope of the Cherenkov Telescope Array observatory

Energy Technology Data Exchange (ETDEWEB)

Konno, Y.; Kubo, H.; Masuda, S. [Department of Physics, Graduate School of Science, Kyoto University, Kyoto (Japan); Paoletti, R.; Poulios, S. [SFTA Department, Physics Section, University of Siena and INFN, Siena (Italy); Rugliancich, A., E-mail: andrea.rugliancich@pi.infn.it [SFTA Department, Physics Section, University of Siena and INFN, Siena (Italy); Saito, T. [Department of Physics, Graduate School of Science, Kyoto University, Kyoto (Japan)

2016-07-11

The Cherenkov Telescope Array (CTA) is the next generation VHE γ-ray observatory which will improve the currently available sensitivity by a factor of 10 in the range 100 GeV to 10 TeV. The array consists of different types of telescopes, called large size telescope (LST), medium size telescope (MST) and small size telescope (SST). A LST prototype is currently being built and will be installed at the Observatorio Roque de los Muchachos, island of La Palma, Canary islands, Spain. The readout system for the LST prototype has been designed and around 300 readout boards will be produced in the coming months. In this note we describe an automated quality control system able to measure basic performance parameters and quickly identify faulty boards. - Highlights: • The Dragon Board is part of the DAQ of the LST Cherenkov telescope prototype. • We developed an automated quality control system for the Dragon Board. • We check pedestal, linearity, pulse shape and crosstalk values. • The quality control test can be performed on the production line.

Frequency and clinical correlates of elevated plasma Epstein-Barr virus DNA at diagnosis in peripheral T-cell lymphomas

Science.gov (United States)

Haverkos, Bradley M.; Huang, Ying; Gru, Alejandro; Pancholi, Preeti; Freud, Aharon G.; Mishra, Anjali; Ruppert, Amy S.; Baiocchi, Robert A.; Porcu, Pierluigi

2016-01-01

Epstein Barr virus (EBV)-encoded RNAs (EBER) in tumor tissue and cell-free plasma EBV-DNA (pEBVd) are detected in EBV-associated lymphomas. Studies have suggested that EBER+ peripheral T-cell lymphomas (PTCL) have worse prognosis, but the role of EBV in these neoplasms remains unclear. pEBVd is quantitative and more easily amenable to standardization than EBER, but frequency of pEBVd detection, clinical impact, and agreement with EBER status in PTCL are unknown. We retrospectively assessed frequency of detectable pre-treatment pEBVd, presence of EBER in tumor tissue, and outcomes in 61 of 135 EBV-assessable PTCL patients. Fifteen of 61 patients (24.5%, 95% CI: 14–37%) were pre-treatment pEBVd+, with no significant differences in baseline characteristics or treatment between pEBVd+ and pEBVd− patients. EBER-ISH was performed on 10 pEBVd+ and 35 pEBVd− tumors. All 10 pEBVd+ patients were EBER+, but 9 pEBVd− patients were also EBER+. With median follow up of 24 months (range 1–96), overall survival (OS) was shorter in pEBVd+ compared to pEBVd− patients (13 vs. 72 months; p=0.04). In this retrospective study, pre-treatment pEBVd was elevated in 25% of PTCL patients, was highly specific for EBER+ tumors, and was associated with shorter survival. pEBVd should be further explored as a prognostic variable and tumor biomarker in PTCL. PMID:27943278

A MIT-Based Nonlinear Adaptive Set-Membership Filter for the Ellipsoidal Estimation of Mobile Robots' States

Directory of Open Access Journals (Sweden)

Dalei Song

2012-10-01

Full Text Available The adaptive extended set-membership filter (AESMF for nonlinear ellipsoidal estimation suffers a mismatch between real process noise and its set boundaries, which may result in unstable estimation. In this paper, a MIT method-based adaptive set-membership filter, for the optimization of the set boundaries of process noise, is developed and applied to the nonlinear joint estimation of both time-varying states and parameters. As a result of using the proposed MIT-AESMF, the estimation effectiveness and boundary accuracy of traditional AESMF are substantially improved. Simulation results have shown the efficiency and robustness of the proposed method.

Striking similarities are exhibited by two small Epstein-Barr virus-encoded ribonucleic acids and the adenovirus-associated ribonucleic acids VAI and VAII

Energy Technology Data Exchange (ETDEWEB)

Rosa, M.D.; Gottlieb, E.; Lerner, M.R.; Steitz, J.A.

1981-09-01

The nucleotide sequence of the region of the Epstein-Barr virus genome that specified two small ribonucleic acids (RNAs), EBER 1 and EBER 2, has been determined. Both of these RNAs are encoded by the right-hand 1,000 base pairs of the EcoRI J fragment of EBV deoxyribonucleic acid. EBER 1 is 166 (167) nucleotides long and EBER 2 is 172 +- 1 nucleotides long; the heterogeneity resides at the 3' termini. The EBER genes are separated by 161 base pairs and are transcribed from the same deoxyribonucleic acid strand. In vitro, both EBER genes can be transcribed by RNA polymerase III; sequences homologous to previously identified RNA polymerase III intragenic transcription control regions are present. Striking similarities are therefore apparent both between the EBERs and the two adenovirus-associated RNAs, VAI and VAII, and between the regions of the two viral genomes that specify these small RNAs. We have shown that VAII RNA as well as VAI RNA and the EBERs exist in ribonucleoprotein complexes which are precipitable by anti-La antibodies associated with systemic lupus erythematosus. Finally the authors have demonstrated that the binding of protein(s) from uninfected cells confers antigenicity on each of the four virus-encoded small RNAs.

VLTI auxiliary telescopes: a full object-oriented approach

Science.gov (United States)

Chiozzi, Gianluca; Duhoux, Philippe; Karban, Robert

2000-06-01

The Very Large Telescope (VLT) Telescope Control Software (TCS) is a portable system. It is now in use or will be used in a whole family of ESO telescopes VLT Unit Telescopes, VLTI Auxiliary Telescopes, NTT, La Silla 3.6, VLT Survey Telescope and Astronomical Site Monitors in Paranal and La Silla). Although it has been developed making extensive usage of Object Oriented (OO) methodologies, the overall development process chosen at the beginning of the project used traditional methods. In order to warranty a longer lifetime to the system (improving documentation and maintainability) and to prepare for future projects, we have introduced a full OO process. We have taken as a basis the United Software Development Process with the Unified Modeling Language (UML) and we have adapted the process to our specific needs. This paper describes how the process has been applied to the VLTI Auxiliary Telescopes Control Software (ATCS). The ATCS is based on the portable VLT TCS, but some subsystems are new or have specific characteristics. The complete process has been applied to the new subsystems, while reused code has been integrated in the UML models. We have used the ATCS on one side to tune the process and train the team members and on the other side to provide a UML and WWW based documentation for the portable VLT TCS.

Computerunterstützte Sacherschließung mit dem Digitalen Assistenten (DA-2

Directory of Open Access Journals (Sweden)

Imma Hinrichs

2016-12-01

Full Text Available Wir beschreiben den Digitalen Assistenten DA-2, den wir zur Unterstützung der Sacherschliessung im IBS-Verbund implementiert haben. Diese webbasierte Anwendung ist eine vollständige Neuimplementierung, welche die Erkenntnisse des Vorgängersystems bei der Zentralbibliothek Zürich berücksichtigt. Wir stellen Überlegungen zur Zukunft der Sacherschliessung an und geben eine Übersicht über Projekte mit ähnlichen Zielsetzungen, die Sacherschließung mit Computerunterstützung effizienter und besser zu gestalten.   We describe the digital assistant DA-2 which we have implemented to support the subject indexing process in the IBS-Verbund. This web-based service is a new implementation from scratch based on the lessons learned with its predecessor used by the Zentralbibliothek Zürich. We also discuss the future of intellectual subject indexing and we give an overview on related projects also aiming at digitizing and economizing this challenging process.

KoelnArena has 18,000 seats; Die KoelnArena mit 18 000 Sitzplaetzen

Energy Technology Data Exchange (ETDEWEB)

Zerres, E.

1999-06-01

The ``Koelnarena`` is a new hall with 18,000 seats for sports events and cultural events, and with a skating rink in the hall center. In view of the many events (up to 180 per year), the skating rink must be glazed throughout the year (except for the summer holidays) in order to avoid the high cost of frequent freezing and thawing. [Deutsch] Die Koelnarena ist eine neue Halle fuer 18 000 Besucher in Koeln-Deutz, mit vielfacher Verwendbarkeit fuer Eishockey und Eistanz, Tennis, Volleyball, Boxen, Schausport, Showkonzerte, Oper und Tanzveranstaltungen. Das Kernstueck dieser MEGA-Halle ist die Eispiste in der Hallenmitte. Wegen der hohen Auslastung der Halle mit bis zu 180 Veranstaltungen pro Jahr muss die Eispiste ganzjaehrig (ausser waehrend der Sommerferien) vereist bleiben, um den sehr grossen Energieaufwand fuer haeufig Eisbildung (und Abtauen.) sowie die Kosten hierfuer zu vermeiden. (orig.)

Kombinierte Hoch-/Niedrig-Dosis-Therapie mit systemischen Glukokor-tikoiden bei schweren Verlaufsformen der Alopecia areata im Kindesalter.

Science.gov (United States)

Jahn-Bassler, Karin; Bauer, Wolfgang Michael; Karlhofer, Franz; Vossen, Matthias G; Stingl, Georg

2017-01-01

Schwere Verlaufsformen der Alopecia areata (AA) im Kindesalter sind aufgrund limitierter Optionen therapeutisch herausfordernd. Systemische, hochdosierte Glukokortikoide weisen die schnellste Ansprechrate auf, nach dem Absetzen kommt es allerdings zu Rezidiven. Eine längerfristige Hochdosis-Anwendung ist aufgrund der zu erwartenden Nebenwirkungen nicht empfehlenswert. Eine dauerhafte Steroiderhaltungstherapie unterhalb der Cushing-Schwellen-Dosis nach Bolustherapie könnte die Krankheitsaktivität ohne Nebenwirkungen längerfristig unterdrücken. Im Rahmen einer offenen Anwendungsbeobachtung wurden 13 Kinder mit schweren Formen der AA in diese Studie eingeschlossen. Bei sieben Kindern lag eine AA totalis/universalis vor, bei sechs eine multifokale AA mit Befall von mehr als 50 % der Kopfhaut. Das Therapieregime sah eine initiale Prednisolon-Dosierung von 2 mg/kg Körpergeweicht (KG) vor und wurde innerhalb von neun Wochen auf eine Erhaltungsdosierung unter der individuellen Cushing-Schwelle reduziert. Der Nachbeobachtungszeitraum betrug ein bis drei Jahre. Wir beobachteten in 62 % aller Fälle ein komplettes Nachwachsen der Haare. Die mittlere Dauer bis zum Ansprechen lag bei 6,6 Wochen und konnte mit der Erhaltungstherapie über den gesamten Beobachtungszeitraum aufrechterhalten werden. An Nebenwirkungen wurden ausschließlich eine Gewichtszunahme (1-3 kg) bei allen Behandelten sowie eine milde Steroidakne in 23 % der Fälle beobachtet. Die kombinierte Hoch-/Niedrig-Dosis-Therapie mit systemischen Glukokortikoiden mittels Prednisolon zeigte eine hohe, dauerhafte Ansprechrate ohne signifikante Nebenwirkungen. © 2017 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

The TACTIC atmospheric Cherenkov imaging telescope

International Nuclear Information System (INIS)

Koul, R.; Tickoo, A.K.; Kaul, S.K.; Kaul, S.R.; Kumar, N.; Yadav, K.K.; Bhatt, N.; Venugopal, K.; Goyal, H.C.; Kothari, M.; Chandra, P.; Rannot, R.C.; Dhar, V.K.; Koul, M.K.; Kaul, R.K.; Kotwal, S.; Chanchalani, K.; Thoudam, S.; Chouhan, N.; Sharma, M.; Bhattacharyya, S.; Sahayanathan, S.

2007-01-01

The TACTIC (TeV Atomospheric Cherenkov Telescope with Imaging Camera) γ-ray telescope, equipped with a light collector of area ∼9.5m 2 and a medium resolution imaging camera of 349 pixels, has been in operation at Mt. Abu, India, since 2001. This paper describes the main features of its various subsystems and its overall performance with regard to (a) tracking accuracy of its two-axes drive system, (b) spot size of the light collector, (c) back-end signal processing electronics and topological trigger generation scheme, (d) data acquisition and control system and (e) relative and absolute gain calibration methodology. Using a trigger field-of-view of 11x11 pixels (∼3.4 a tx3.4 a t), the telescope records a cosmic ray event rate of ∼2.5Hz at a typical zenith angle of 15 a t. Monte Carlo simulation results are also presented in the paper for comparing the expected performance of the telescope with actual observational results. The consistent detection of a steady signal from the Crab Nebula above ∼1.2TeV energy, at a sensitivity level of ∼5.0σ in ∼25h, along with excellent matching of its energy spectrum with that obtained by other groups, reassures that the performance of the TACTIC telescope is quite stable and reliable. Furthermore, encouraged by the detection of strong γ-ray signals from Mrk 501 (during 1997 and 2006 observations) and Mrk 421 (during 2001 and 2005-2006 observations), we believe that there is considerable scope for the TACTIC telescope to monitor similar TeV γ-ray emission activity from other active galactic nuclei on a long-term basis

Simulation of the Simbol-X telescope: imaging performance of a deformable x-ray telescope

Science.gov (United States)

Chauvin, Maxime; Roques, Jean-Pierre

2009-08-01

We have developed a simulation tool for a Wolter I telescope subject to deformations. The aim is to understand and predict the behavior of Simbol-X and other future missions (NuSTAR, Astro-H, IXO, ...). Our code, based on Monte-Carlo ray-tracing, computes the full photon trajectories up to the detector plane, along with the deformations. The degradation of the imaging system is corrected using metrology. This tool allows to perform many analyzes in order to optimize the configuration of any of these telescopes.

FACT. Bokeh alignment for Cherenkov telescopes

Energy Technology Data Exchange (ETDEWEB)

Mueller, Sebastian Achim [ETH Zurich (Switzerland); Buss, Jens [TU Dortmund (Germany)

2016-07-01

Imaging Atmospheric Cherenkov Telescopes (IACTs) need fast and large imaging optics to map the faint Cherenkov light emitted in cosmic ray air showers onto their image sensors. Segmented reflectors are inexpensive, lightweight and offer good image quality. However, alignment of the mirror facets remains a challenge. A good alignment is crucial in IACT observations to separate gamma rays from hadronic cosmic rays. We present a simple, yet extendable method, to align segmented reflectors using their Bokeh. Bokeh alignment does not need a star or good weather nights but can be done anytime, even during the day. Bokeh alignment optimizes the facet orientations by comparing the segmented reflector's Bokeh to a predefined template. The Bokeh is observed using the out of focus image of a nearby point like light source in a distance of about ten times the focal lengths. We introduce Bokeh alignment on segmented reflectors and present its use on the First Geiger-mode Avalanche Cherenkov Telescope (FACT) on Canary Island La Palma, as well as on the Cherenkov Telescope Array (CTA) Medium Size Telescope (MST) prototype in Berlin Adlershof.

Choosing and Using a Refracting Telescope

CERN Document Server

English, Neil

2011-01-01

The refracting telescope has a long and illustrious past. Here’s what the author says about early telescopes and today’s refractors: “Four centuries ago, a hitherto obscure Italian scientist turned a home-made spyglass towards the heavens. The lenses he used were awful by modern standards, inaccurately figured and filled with the scars of their perilous journey from the furnace to the finishing workshop. Yet, despite these imperfections, they allowed him to see what no one had ever seen before – a universe far more complex and dynamic than anyone had dared imagine. But they also proved endlessly useful in the humdrum of human affairs. For the first time ever, you could spy on your neighbor from a distance, or monitor the approach of a war-mongering army, thus deciding the fate of nations. “The refractor is without doubt the prince of telescopes. Compared with all other telescopic designs, the unobstructed view of the refractor enables it to capture the sharpest, highest contrast images and the wides...

Go-To Telescopes Under Suburban Skies

CERN Document Server

Monks, Neale

2010-01-01

For the last four centuries stargazers have turned their telescopes to the night skies to look at its wonders, but only in this age of computers has it become possible to let the telescope find for you the object you are looking for! So-called “go-to” telescopes are programmed with the locations of thousands of objects, including dazzling distant Suns, stunning neighboring galaxies, globular and open star clusters, the remnants of past supernovae, and many other breathtaking sights. This book does not tell you how to use your Go-to telescope. Your manual will help you do that. It tells you what to look for in the deep sky and why, and what equipment to best see it with. Organized broadly by what is best for viewing in the northern hemisphere in different seasons, Monks further divides the sights of each season into groupings such as “Showpiece Objects,” “Interesting Deep Sky Objects,” and “Obscure and Challenging Deep Sky Objects.” He also tells what objects are visible even in light-polluted ...

Einfluss des Alltagskontextes auf den Prozess einer Ernährungsverhaltensmodifikation : eine qualitative Untersuchung von Personen mit erhöhten Cholesterinwerten

OpenAIRE

Hildebrandt, Karen

2012-01-01

Das erkenntnisleitende Forschungsinteresse gilt einer umfassenden Betrachtung ernährungsbezogenen Handelns in den drei Alltagsbereichen „Haushalt/Familie“, „Arbeitsplatz/Kollegen“ und „Freizeit/Freunde“ mit dem Ziel, individuell erlebte Bedingungen und Faktoren einer Ernährungsverhaltensmodifikation herauszuarbeiten. In die Untersuchung sind Personen mit einer Fettstoffwechselstörung eingeschlossen worden, die sich in verschiedenen Stadien einer Gesundheitsverhaltensmodifikation befinden. ...

Telescoping cylindrical piezoelectric fiber composite actuator assemblies

Science.gov (United States)

Allison, Sidney G. (Inventor); Shams, Qamar A. (Inventor); Fox, Robert L. (Inventor); Fox, legal representative, Christopher L. (Inventor); Fox Chattin, legal representative, Melanie L. (Inventor)

2010-01-01

A telescoping actuator assembly includes a plurality of cylindrical actuators in a concentric arrangement. Each cylindrical actuator is at least one piezoelectric fiber composite actuator having a plurality of piezoelectric fibers extending parallel to one another and to the concentric arrangement's longitudinal axis. Each cylindrical actuator is coupled to concentrically-adjacent ones of the cylindrical actuators such that the plurality of cylindrical actuators can experience telescopic movement. An electrical energy source coupled to the cylindrical actuators applies actuation energy thereto to generate the telescopic movement.

Neutrino telescopes sensitivity to dark matter

International Nuclear Information System (INIS)

Albuquerque, I.F.M.; Lamoureux, J.; Smoot, G.F.

2002-01-01

The nature of the dark matter of the Universe is yet unknown and most likely is connected with new physics. The search for its composition is underway through direct and indirect detection. Fundamental physical aspects such as energy threshold, geometry and location are taken into account to investigate proposed neutrino telescopes of km3 volume sensitivities to dark matter. These sensitivities are just sufficient to test a few weakly interacting massive particle scenarios. Telescopes of km3 volume, such as IceCube, can definitely discover or exclude superheavy (M>1010 GeV) strong interacting massive particles (simpzillas). Smaller neutrino telescopes such as ANTARES, AMANDA-II and NESTOR can probe a large region of simpzilla parameter space

[COPD und Klangtherapie: Pilotstudie zur Wirksamkeit einer Behandlung mit Körpertambura bei COPD-Patienten].

Science.gov (United States)

Hartwig, Bernhard; Schmidt, Stefan; Hartwig, Isabella

2016-01-01

Hintergrund: Erkrankungen der Atemorgane treten mit steigendem Alter öfter auf, nehmen weltweit zu und sind häufige Ursachen für Morbidität und Mortalität. In dieser Pilotstudie wurde der Frage nachgegangen, ob eine einmalige 10-minütige Behandlung mit einer Körpertambura eine signifikante und effektive Verbesserung der Lungenfunktion von Patienten mit chronisch-obstruktiver Lungenerkrankung (COPD; GOLD-Stadium A oder B) erbringen kann. Patienten und Methoden: 54 Probanden konnten je zur Hälfte in eine Behandlungsgruppe (Körpertambura) und eine aktive Kontrollgruppe (Atemtherapie) randomisiert werden. Eine Bestimmung der Lungenfunktionsmessparameter «Einsekundenkapazität» (FEV1) und «inspiratorische Vitalkapazität» (IVC) zu den Zeitpunkten T1 (Baseline), T2 (direkt nach Behandlung) und als Follow-up etwa 3 Wochen nach T1 (T3). Ergebnisse: Die Behandlungsgruppe zeigte sich der Kontrollgruppe in beiden Werten signifikant überlegen. Die Zeit-×-Gruppe-Interaktion (Varianzanalyse) ergab p = 0,001 (FEV1) bzw. p = 0,04 (IVC). Die Behandlungsgruppe zeigte bei beiden Werten eine Verbesserung von klinischer Relevanz. Schlussfolgerung: Diese Ergebnisse zeigen, dass die Klangbehandlung mittels einer Körpertambura - neben den schulmedizinischen, leitliniengerechten Therapien - eine zusätzliche, nebenwirkungsarme, aber durchaus klinisch wirksame Option für die Behandlung von COPD-Patienten darstellen kann, um deren Lebensqualität zu stabilisieren und zu verbessern. © 2016 S. Karger GmbH, Freiburg.

Fast Fourier transform telescope

International Nuclear Information System (INIS)

Tegmark, Max; Zaldarriaga, Matias

2009-01-01

We propose an all-digital telescope for 21 cm tomography, which combines key advantages of both single dishes and interferometers. The electric field is digitized by antennas on a rectangular grid, after which a series of fast Fourier transforms recovers simultaneous multifrequency images of up to half the sky. Thanks to Moore's law, the bandwidth up to which this is feasible has now reached about 1 GHz, and will likely continue doubling every couple of years. The main advantages over a single dish telescope are cost and orders of magnitude larger field-of-view, translating into dramatically better sensitivity for large-area surveys. The key advantages over traditional interferometers are cost (the correlator computational cost for an N-element array scales as Nlog 2 N rather than N 2 ) and a compact synthesized beam. We argue that 21 cm tomography could be an ideal first application of a very large fast Fourier transform telescope, which would provide both massive sensitivity improvements per dollar and mitigate the off-beam point source foreground problem with its clean beam. Another potentially interesting application is cosmic microwave background polarization.

Liverpool Telescope 2: beginning the design phase

Science.gov (United States)

Copperwheat, Christopher M.; Steele, Iain A.; Barnsley, Robert M.; Bates, Stuart D.; Bode, Mike F.; Clay, Neil R.; Collins, Chris A.; Jermak, Helen E.; Knapen, Johan H.; Marchant, Jon M.; Mottram, Chris J.; Piascik, Andrzej S.; Smith, Robert J.

2016-07-01

The Liverpool Telescope is a fully robotic 2-metre telescope located at the Observatorio del Roque de los Muchachos on the Canary Island of La Palma. The telescope began routine science operations in 2004, and currently seven simultaneously mounted instruments support a broad science programme, with a focus on transient followup and other time domain topics well suited to the characteristics of robotic observing. Work has begun on a successor facility with the working title `Liverpool Telescope 2'. We are entering a new era of time domain astronomy with new discovery facilities across the electromagnetic spectrum, and the next generation of optical survey facilities such as LSST are set to revolutionise the field of transient science in particular. The fully robotic Liverpool Telescope 2 will have a 4-metre aperture and an improved response time, and will be designed to meet the challenges of this new era. Following a conceptual design phase, we are about to begin the detailed design which will lead towards the start of construction in 2018, for first light ˜2022. In this paper we provide an overview of the facility and an update on progress.

The Telescope: Outline of a Poetic History

Science.gov (United States)

Stocchi, M. P.

2011-06-01

Amongst the first editions of Galileo's books, only the Saggiatore has on its frontispiece the image of the telescope. Indeed, the telescope is not pictured on the very emphatic frontispieces of the other books in which Galileo was presenting and defending the results achieved by his celestial observations, such as the Sidereus Nuncius. Many contemporary scientists denied the reliability of the telescope, and some even refused to look into the eyepiece. In the 16th and 17th century, the lenses, mirrors, and optical devices of extraordinary complexity did not have the main task of leading to the objective truth but obtaining the deformation of the reality by means of amazing effects of illusion. The Baroque art and literature had the aim of surprising, and the artists gave an enthusiastic support to the telescope. The poems in praise of Galileo's telescopic findings were quite numerous, including Adone composed by Giovanni Battista Marino, one of the most renowned poets of the time. The Galilean discoveries were actually accepted by the poets as ideologically neutral contributions to the "wonder" in spite they were rejected or even condemned by the scientists, philosophers, and theologians.

Development and Performances of the Magic Telescope

Science.gov (United States)

Bastieri, D.; Bigongiari, C.; Dazzi, F.; Mariotti, M.; Moralejo, A.; Peruzzo, L.; Saggion, A.; Tonello, N.

2002-11-01

The MAGIC Collaboration is building an imaging Čerenkov telescope at La Palma site (2200 m a.s.l.), in the Canary Islands, to observe gamma rays in the hundred-GeV region. The MAGIC telescope, with its reflecting parabolic dish, 17 m in diameter, and a two-level pattern trigger designed to cope with severe trigger rates, is the Čerenkov telescope with the lowest envisaged energy threshold. Due to its lightweight alto-azimuthal mounting, MAGIC can be repositioned in less than 30 seconds, becoming the only detector, with an adequate effective area, capable to observe GRB phenomena above 30 GeV. MAGIC telescope is characterised by a 30 GeV energy threshold and a sensitivity of 6×l0-11 cm-2s-1 for a 5σ-detection in 50-hours of observation. In this report, some future scientific goals for MAGIC will be highlighted and the technical development for the main elements of the telescope will be detailed. Special emphasis will be given to the construction of the individual metallic mirrors which form the reflecting surface and the development of the fast pattern-recognition trigger.

A new concept of imaging system: telescope windows

Science.gov (United States)

Bourgenot, Cyril; Cowie, Euan; Young, Laura; Love, Gordon; Girkin, John; Courtial, Johannes

2018-02-01

A Telescope window is a novel concept of transformation-optics consisting of an array of micro-telescopes, in our configuration, of a Galilean type. When the array is considered as one multifaceted device, it acts as a traditional Galilean telescope with distinctive and attractive properties such as compactness and modularity. Each lenslet, can in principle, be independently designed for a specific optical function. In this paper, we report on the design, manufacture and prototyping, by diamond precision machining, of 2 concepts of telescope windows, and discuss both their performances and limitations with a view to use them as potential low vision aid devices to support patients with macular degeneration.

GISOT: a giant solar telescope

Science.gov (United States)

Hammerschlag, Robert H.; von der Lühe, Oskar F.; Bettonvil, Felix C.; Jägers, Aswin P.; Snik, Frans

2004-10-01

A concept is presented for an extremely large high-resolution solar telescope with an aperture of 11 m and diffraction limited for visual wavelengths. The structure of GISOT will be transparent to wind and placed on a transparent stiff tower. For efficient wind flushing, all optics, including the primary mirror, will be located above the elevation axis. The aperture will be of the order of 11 m, not rotatively symmetrical, but of an elongated shape with dimensions 11 x 4 m. It consists of a central on-axis 4 m mirror with on both sides 3 pieces of 2 m mirrors. The optical layout will be kept simple to guarantee quality and minimize stray light. A Coudé room for instruments is planned below the telescope. The telescope will not be housed in a dome-like construction, which interferes with the open principle. Instead the telescope will be protected by a foldable tent construction with a diameter of the order of 30 m, which doesn"t form any obstruction during observations, but can withstand the severe weather circumstances on mountain sites. Because of the nature of the solar scene, extremely high resolution in only one dimension is sufficient to solve many exciting problems in solar physics and in this respect the concept of GISOT is very promising.

Undergraduate Education with the WIYN 0.9-m Telescope

Science.gov (United States)

Pilachowski, Catherine A.

2017-01-01

Several models have been explored at Indiana University Bloomington for undergraduate student engagement in astronomy using the WIYN 0.9-m telescope at Kitt Peak. These models include individual student research projects using the telescope, student observations as part of an observational techniques course for majors, and enrichment activities for non-science majors in general education courses. Where possible, we arrange for students to travel to the telescope. More often, we are able to use simple online tools such as Skype and VNC viewers to give students an authentic observing experience. Experiences with the telescope motivate students to learn basic content in astronomy, including the celestial sphere, the electromagnetic spectrum, telescopes and detectors, the variety of astronomical objects, date reduction processes, image analysis, and color image creation and appreciation. The WIYN 0.9-m telescope is an essential tool for our program at all levels of undergraduate education

Cost accounting in Kernforschungsanlage Juelich Gesellschaft mit beschraenkter Haftung (KFA)

International Nuclear Information System (INIS)

Seidel, G.; Schilling, H.

1979-01-01

The paper gives an overview about the organization and the research program of the Kernforschungsanalage Juelich Gesellschaft mit beschraenkter Haftung (KFA). The cost accounting system is discussed in detail, cost categories, cost centers, units of production and the data flow of the cost accounting are described. The distribution of the resulting management accounting reports and all sorts of EDP-result listings of the cost accounting system is described. (A.N.)

A review of the MIT experiments on the closed-loop digital control of reactor power

International Nuclear Information System (INIS)

Bernard, J.A.

1989-01-01

In this paper a review is provided of certain major experiments conducted from 1985 to 1988 as part of the MIT program on the development and demonstration of advanced technologies for the closed-loop digital control of nuclear reactors. Included are demonstrations of the supervisory control of neutronic power using an alternate formulation of the dynamic period equation, the use of the MIT-SNL Period-Generated Minimum Time Control Laws for the time-optimal control of neutronic power, and the evaluation of predictive displays as an operator aid. The significance of each of these advances is discussed in terms of the overall development of a multi-tiered controller that includes supervisory algorithms, predictive control laws, and automated reasoning

Aplanatic telescopes based on Schwarzschild optical configuration: from grazing incidence Wolter-like x-ray optics to Cherenkov two-mirror normal incidence telescopes

Science.gov (United States)

Sironi, Giorgia

2017-09-01

At the beginning of XX century Karl Schwarzschild defined a method to design large-field aplanatic telescopes based on the use of two aspheric mirrors. The approach was then refined by Couder (1926) who, in order to correct for the astigmatic aberration, introduced a curvature of the focal plane. By the way, the realization of normal-incidence telescopes implementing the Schwarzschild aplanatic configuration has been historically limited by the lack of technological solutions to manufacture and test aspheric mirrors. On the other hand, the Schwarzschild solution was recovered for the realization of coma-free X-ray grazing incidence optics. Wolter-like grazing incidence systems are indeed free of spherical aberration, but still suffer from coma and higher order aberrations degrading the imaging capability for off-axis sources. The application of the Schwarzschild's solution to X-ray optics allowed Wolter to define an optical system that exactly obeys the Abbe sine condition, eliminating coma completely. Therefore these systems are named Wolter-Schwarzschild telescopes and have been used to implement wide-field X-ray telescopes like the ROSAT WFC and the SOHO X-ray telescope. Starting from this approach, a new class of X-ray optical system was proposed by Burrows, Burg and Giacconi assuming polynomials numerically optimized to get a flat field of view response and applied by Conconi to the wide field x-ray telescope (WFXT) design. The Schwarzschild-Couder solution has been recently re-discovered for the application to normal-incidence Cherenkov telescopes, thanks to the suggestion by Vassiliev and collaborators. The Italian Institute for Astrophysics (INAF) realized the first Cherenkov telescope based on the polynomial variation of the Schwarzschild configuration (the so-called ASTRI telescope). Its optical qualification was successfully completed in 2016, demonstrating the suitability of the Schwarzschild-like configuration for the Cherenkov astronomy requirements

MiT family translocation renal cell carcinoma.

Science.gov (United States)

Argani, Pedram

2015-03-01

The MiT subfamily of transcription factors includes TFE3, TFEB, TFC, and MiTF. Gene fusions involving two of these transcription factors have been identified in renal cell carcinoma (RCC). The Xp11 translocation RCCs were first officially recognized in the 2004 WHO renal tumor classification, and harbor gene fusions involving TFE3. The t(6;11) RCCs harbor a specific Alpha-TFEB gene fusion and were first officially recognized in the 2013 International Society of Urologic Pathology (ISUP) Vancouver classification of renal neoplasia. These two subtypes of translocation RCC have many similarities. Both were initially described in and disproportionately involve young patients, though adult translocation RCC may overall outnumber pediatric cases. Both often have unusual and distinctive morphologies; the Xp11 translocation RCCs frequently have clear cells with papillary architecture and abundant psammomatous bodies, while the t(6;11) RCCs frequently have a biphasic appearance with both large and small epithelioid cells and nodules of basement membrane material. However, the morphology of these two neoplasms can overlap, with one mimicking the other. Both of these RCCs underexpress epithelial immunohistochemical markers like cytokeratin and epithelial membrane antigen (EMA) relative to most other RCCs. Unlike other RCCs, both frequently express the cysteine protease cathepsin k and often express melanocytic markers like HMB45 and Melan A. Finally, TFE3 and TFEB have overlapping functional activity as these two transcription factors frequently heterodimerize and bind to the same targets. Therefore, on the basis of clinical, morphologic, immunohistochemical, and genetic similarities, the 2013 ISUP Vancouver classification of renal neoplasia grouped these two neoplasms together under the heading of "MiT family translocation RCC." This review summarizes our current knowledge of these recently described RCCs. Copyright © 2015 Elsevier Inc. All rights reserved.

Radio telescope control

CERN Document Server

Schraml, J

1972-01-01

An on-line computer control process developed for the 100-m radio telescope of the Max-Planck-Institut fur Radioastronomie in Bonn is described. The instrument is the largest fully steerable antenna in the world. Its operation started on May 31st 1972. It is controlled by a Ferranti Argus 500 on-line computer. The first part of the paper deals with the process itself, the radio telescope and its operation, and the demands resulting for the control program. The second part briefly describes the computer and its hardware. The final part introduces the architecture of the executive program in general, which has been tailored to meet the demands of the process and the hardware. The communication between the observer and the system, the format of data on magnetic tape and an on-line reduction of position measurements are considered. (0 refs).

The JCMT Telescope Management System

Science.gov (United States)

Tilanus, Remo P. J.; Jenness, Tim; Economou, Frossie; Cockayne, Steve

Established telescopes often face a challenge when trying to incorporate new software standards and utilities into their existing real-time control system. At the JCMT we have successfully added important new features such as a Relational Database (the Telescope Management System---TMS), an online data Archive, and WWW based utilities to an, in part, 10-year old system. The new functionality was added with remarkably few alterations to the existing system. We are still actively expanding and exploring these new capabilities.

Development of Slewing Mirror Telescope Optical System for the UFFO-pathfinder

DEFF Research Database (Denmark)

Jeong, S.; Nam, J.W.; Ahn, K.-B.

2013-01-01

The Slewing Mirror Telescope (SMT) is the UV/optical telescope of UFFO-pathfinder. The SMT optical system is a Ritchey-Chrétien (RC) telescope of 100 mm diameter pointed by means of a gimbal-mounted flat mirror in front of the telescope. The RC telescope has a 17 × 17arcmin2 in Field of View and ...

Academic Training: Deep Space Telescopes

CERN Multimedia

Françoise Benz

2006-01-01

2005-2006 ACADEMIC TRAINING PROGRAMME LECTURE SERIES 20, 21, 22, 23, 24 February from 11:00 to 12:00 - Council Chamber on 20, 21, 23, 24 February, TH Auditorium, bldg 4 - 3-006, on 22 February Deep Space Telescopes G. BIGNAMI / CNRS, Toulouse, F & Univ. di Pavia, I The short series of seminars will address results and aims of current and future space astrophysics as the cultural framework for the development of deep space telescopes. It will then present such new tools, as they are currently available to, or imagined by, the scientific community, in the context of the science plans of ESA and of all major world space agencies. Ground-based astronomy, in the 400 years since Galileo's telescope, has given us a profound phenomenological comprehension of our Universe, but has traditionally been limited to the narrow band(s) to which our terrestrial atmosphere is transparent. Celestial objects, however, do not care about our limitations, and distribute most of the information about their physics thro...

[Osteopathie bei gastroösophagealem Reflux mit Hiatushernie: Ein Fallbericht gemäß der CARE-Leitlinie].

Science.gov (United States)

Rotter, Gabriele; Brinkhaus, Benno

2017-01-01

Hintergrund: Das Vorhandensein einer Hiatushernie kann das Auftreten einer gastroösophagealen Refluxerkrankung (GERD) als Komplikation bedingen. Konventionelle medizinische Therapiemaßnahmen können zu unerwünschten Ereignissen und Rezidiven führen. Bisher sind die Effekte von osteopathischen Behandlungen bei Hiatushernie und GERD nicht bekannt. Fallbericht: Eine 59-jährige Patientin mit endoskopisch diagnostizierter chronischer Gastritis, GERD und Hiatushernie beklagte einen persistierenden gastroösophagealen Reflux trotz konventionell-medizinischer konservativer Therapie. Die osteopathische Diagnostik ergab eine funktionelle Störung im Bereich des Magens und der Kardia mit einer Beteiligung zugehöriger Reflexzonen. Nach einer osteopathischen Behandlung als individuelle, befundorientierte Therapie ließen die Beschwerden erheblich nach. Die Hiatushernie war nach einer dieser Behandlung endoskopisch nicht mehr nachweisbar. Schlussfolgerungen: Dieser Fallbericht schildert die Symptomreduktion einer GERD nach osteopathischer Behandlung. In der endoskopischen Folgeuntersuchung fand sich die initial diagnostizierte Hiatushernie nicht mehr, diese Befund änderung könnte jedoch auf die unterschiedlichen Untersucher zurückgeführt werden. Prospektive kontrollierte klinische Studien sind notwendig, um den Stellenwert von osteopathischen Behandlungen bei GERD mit Hiatushernie zu untersuchen. © 2017 The Author(s). Published by S. Karger GmbH, Freiburg.

Observations of Anomalous Refraction with Co-housed Telescopes

Science.gov (United States)

Taylor, Malinda S.; McGraw, J. T.; Zimmer, P. C.

2013-01-01

Anomalous refraction is described as a low frequency, large angular scale motion of the entire image plane with respect to the celestial coordinate system as observed and defined by previous astrometric catalogs. These motions of typically several tenths of an arcsecond with timescales on the order of ten minutes are ubiquitous to drift-scan ground-based astrometric measurements regardless of location or telescopes used and have been attributed to meter scale slowly evolving coherent dynamical structures in the boundary-layer below 60 meters. The localized nature of the effect and general inconsistency of the motions seen by even closely spaced telescopes in individual domes has led to the hypothesis that the dome or other type of telescope housing may be responsible. This hypothesis is tested by observing anomalous refraction using two telescopes housed in a single roll-off roof observatory building with the expected outcome that the two telescopes will see correlated anomalous refraction induced motions.

Ideas for future large single dish radio telescopes

Science.gov (United States)

Kärcher, Hans J.; Baars, Jacob W. M.

2014-07-01

The existing large single dish radio telescopes of the 100m class (Effelsberg, Green Bank) were built in the 1970s and 1990s. With some active optics they work now down to 3 millimeter wavelength where the atmospheric quality of the site is also a limiting factor. Other smaller single dish telescopes (50m LMT Mexico, 30m IRAM Spain) are located higher and reach sub-millimeter quality, and the much smaller 12m antennas of the ALMA array reach at a very high site the Terahertz region. They use advanced technologies as carbon fiber structures and flexible body control. We review natural limits to telescope design and use the examples of a number of telescopes for an overview of the available state-of-the-art in design, engineering and technologies. Without considering the scientific justification we then offer suggestions to realize ultimate performance of huge single dish telescopes (up to 160m). We provide an outlook on design options, technological frontiers and cost estimates.

Revisiting the Effectiveness of Large Optical Telescopes

Directory of Open Access Journals (Sweden)

V. V. Sychev

2015-01-01

Full Text Available To create large-size optical telescopes, various design concepts have been used. Each concept inevitably faced the challenge to optimize technical characteristics and parameters of the telescope. There was always a question: what concept to choose, how to estimate efficiency of such telescopes and by what criteria and how to estimate expediency of this or that project of the large-size telescope. It is, obviously, insufficient to make a resolution-based estimation. An estimate by the angular field size is inappropriate too. Well, it may be also an estimate by the stellar magnitude. All these criteria are related to each other. Improvement of one of these parameters inevitably leads to deterioration of the others. Obviously, the certain generalized criterion considering all parameters and features of the design concept of the large-size telescope is necessary here. As such can serve the criterion of informational content of the telescope.The article offers a complex criterion allowing not only to estimate efficiency of large-size optical telescopes, but also to compare their conceptual and technological level among themselves in terms of obtaining information.The article suggests a new term, i.e. the informational content invariant to characterize informative capacities of the chosen concept and of the realizing technology. It will allow us to avoid unjustified complications of technical solutions, wrong accents in designing and excess material inputs when developing the project.The informational content criterion-based analysis of the existing projects of large-size telescopes has been convincingly shown that, conceptually, there are three best telescopes, namely: GSMT, CELT, and ACT-25. And, in terms of informational content, the АCТ-25 is 10 times more than GSMT and CELT, and the existing Keck-telescope exceeds by 30 times. Hence, it is hard to escape a conclusion that it is more favourable to implement one ACT-25, than to do 10 GSMT or CELT

Simulation of the Simbol-X Telescope

International Nuclear Information System (INIS)

Chauvin, M.; Roques, J. P.

2009-01-01

We have developed a simulation tool for a Wolter I telescope operating in formation flight. The aim is to understand and predict the behavior of the Simbol-X instrument. As the geometry is variable, formation flight introduces new challenges and complex implications. Our code, based on Monte Carlo ray tracing, computes the full photon trajectories up to the detector plane, along with the relative drifts of the two spacecrafts. It takes into account angle and energy dependent interactions of the photons with the mirrors and applies to any grazing incidence telescope. The resulting images of simulated sources from 0.1 keV to 100 keV allow us to optimize the configuration of the instrument and to assess the performance of the Simbol-X telescope.

Simulation of the Simbol-X Telescope

Science.gov (United States)

Chauvin, M.; Roques, J. P.

2009-05-01

We have developed a simulation tool for a Wolter I telescope operating in formation flight. The aim is to understand and predict the behavior of the Simbol-X instrument. As the geometry is variable, formation flight introduces new challenges and complex implications. Our code, based on Monte Carlo ray tracing, computes the full photon trajectories up to the detector plane, along with the relative drifts of the two spacecrafts. It takes into account angle and energy dependent interactions of the photons with the mirrors and applies to any grazing incidence telescope. The resulting images of simulated sources from 0.1 keV to 100 keV allow us to optimize the configuration of the instrument and to assess the performance of the Simbol-X telescope.

The VTIE telescope resource management system

Science.gov (United States)

Busschots, B.; Keating, J. G.

2005-06-01

The VTIE Telescope Resource Management System (TRMS) provides a frame work for managing a distributed group of internet telescopes as a single "Virtual Observatory". The TRMS provides hooks which allow for it to be connected to any Java Based web portal and for a Java based scheduler to be added to it. The TRMS represents each telescope and observatory in the system with a software agent and then allows the scheduler and web portal to communicate with these distributed resources in a simple transparent way, hence allowing the scheduler and portal designers to concentrate only on what they wish to do with these resources rather than how to communicate with them. This paper outlines the structure and implementation of this frame work.

Schwerpunktseminar : "Dazugehören? Umgang mit Minderheiten" / Liliāna Vancāne

Index Scriptorium Estoniae

Vancāne, Liliāna

2016-01-01

17. -20. märtsini 2016 Tartus toimunud seminarist "Dazugehören? Umgang mit Minderheiten. Estland und Lettland gestern-heutu-morgen". Seminarist sotsiaalse kuuluvuse ja vähemuste teemal. Suurepäraselt korraldatud ürituse parim osa oli töötuba

MIT/Draper Technology Development Partnership Project: Systems Analysis and On-Station Propulsion Subsystem Design

National Research Council Canada - National Science Library

Conklin, Theodore

1998-01-01

The objective of this thesis is to describe the process for, and the overall design that resulted from the MIT/Draper Project from August, 1996 to May, 1997, including the specific design of the on...

Direct illumination LED calibration for telescope photometry

International Nuclear Information System (INIS)

Barrelet, E.; Juramy, C.

2008-01-01

A calibration method for telescope photometry, based on the direct illumination of a telescope with a calibrated light source regrouping multiple LEDs, is proposed. Its purpose is to calibrate the instrument response. The main emphasis of the proposed method is the traceability of the calibration process and a continuous monitoring of the instrument in order to maintain a 0.2% accuracy over a period of years. Its specificity is to map finely the response of the telescope and its camera as a function of all light ray parameters. This feature is essential to implement a computer model of the instrument representing the variation of the overall light collection efficiency of each pixel for various filter configurations. We report on hardware developments done for SNDICE, the first application of this direct illumination calibration system which will be installed in Canada France Hawaii telescope (CFHT) for its leading supernova experiment (SNLS)

Construction of the Advanced Technology Solar Telescope

Science.gov (United States)

Rimmele, T. R.; Keil, S.; McMullin, J.; Knölker, M.; Kuhn, J. R.; Goode, P. R.; Rosner, R.; Casini, R.; Lin, H.; Tritschler, A.; Wöger, F.; ATST Team

2012-12-01

The 4m Advance Technology Solar Telescope (ATST) will be the most powerful solar telescope and the world's leading ground-based resource for studying solar magnetism that controls the solar wind, flares, coronal mass ejections and variability in the Sun's output. The project has entered its construction phase. Major subsystems have been contracted. As its highest priority science driver ATST shall provide high resolution and high sensitivity observations of the dynamic solar magnetic fields throughout the solar atmosphere, including the corona at infrared wavelengths. With its 4m aperture, ATST will resolve features at 0.″03 at visible wavelengths and obtain 0.″1 resolution at the magnetically highly sensitive near infrared wavelengths. A high order adaptive optics system delivers a corrected beam to the initial set of state-of-the-art, facility class instrumentation located in the Coudé laboratory facility. The initial set of first generation instruments consists of five facility class instruments, including imagers and spectro-polarimeters. The high polarimetric sensitivity and accuracy required for measurements of the illusive solar magnetic fields place strong constraints on the polarization analysis and calibration. Development and construction of a four-meter solar telescope presents many technical challenges, including thermal control of the enclosure, telescope structure and optics and wavefront control. A brief overview of the science goals and observational requirements of the ATST will be given, followed by a summary of the design status of the telescope and its instrumentation, including design status of major subsystems, such as the telescope mount assembly, enclosure, mirror assemblies, and wavefront correction

Familienbezogene Lebensqualität bei Müttern von Jungen mit Fragilem-X-Syndrom im frühen Kindesalter

OpenAIRE

Sarimski, Klaus

2010-01-01

Die Erfassung familienbezogener Lebensqualität bei Müttern behinderter Kinder richtet sich sowohl auf Einschränkungen, die mit der Erziehung und Versorgung des Kindes für das eigene Leben verbunden sind, wie auch mögliche positive Veränderungen der eigenen Perspektiven. Es ist davon auszugehen, dass die Lebensqualität u. a. vom Alter des Kindes und der Art seiner Behinderung abhängt. Es wird über eine Untersuchung mit dem Fragebogen zur familienbezogenen Lebensqualität (FLQ) berichtet, in der...