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Sample records for hits vilnius streets

  1. Elements of vilnius' infrastructure (lighting and water supply system): aspects of cultural heritage conservation

    OpenAIRE

    Kecoriūtė, Eglė

    2008-01-01

    In 2009 Vilnius is publicized as European Cultural capital. It means that our country lives an active cultural life. It’s like a present to us symbolizing that Lithuanians understand their history, culture and heritage; that they know how to save and use it for esthetical, financial, cultural or other purposes. Object of this work – technical heritage, specifically street lighting and water supply equipment in Vilnius. This is a range of small technical heritage directly related with domestic...

  2. COMPLEX EVALUATION OF ELECTRIC RAIL TRANSPORT IMPLEMENTATION IN VILNIUS CITY

    Directory of Open Access Journals (Sweden)

    Gintautas BUREIKA

    2016-03-01

    Full Text Available The article analyses the current problems of Vilnius city public transportation. The possible solutions (options and the technical means to improve the attractiveness of public transportation and accessibility are considered. Two main alternatives of means of electric transport (underground and tram have been singled out for Vilnius city. The suitability of these rail transport means have been substantiated. The nature and density of the work and residence places (areas of Vilnius city residents have been analysed. The scheme of tram and underground lines projected in Vilnius city are evaluated, which have been composed according to the current and forecasted flows of passengers, the nature of their changes and critical points. The technical economic indicators of the tram routes and underground lines in Vilnius city are analysed: average driving speed, average distance between the stations, the duration of the trip, the capacity of a single means of transport, the costs of line support and the size of investment. The accident rate of urban rail transportation is estimated. Comparative criteria of tram and underground lines are selected. The effectiveness of both rail means of transport in Vilnius city are compared according to three multi-criteria evaluation methods: the sum of ratings, simple additive weighting and geometrical means. The final conclusions and recommendations are provided.

  3. Pirouettes around the Vilnius mayor's post / Rokas M. Tracevskis

    Index Scriptorium Estoniae

    Tracevskis, Rokas M.

    2010-01-01

    Isamaaliidu ja Leedu Kristlike Demokraatide Partei viis läbi esimese salajase hääletuse selgitamaks välja partei esikandidaati 2011. aastal toimuvatel kohalikel valimistel. Vilniuse praegune linnapea Vilius Navickas, kes oli lubanud Vilniuse nõukogudeaegseid monumente likvideerida, teise vooru ei pääsenud

  4. The Vilnius issue in international relations: the historiography of the problem

    Directory of Open Access Journals (Sweden)

    Mankevich Maria

    2012-03-01

    Full Text Available This article considers certain historiographical aspects of the Vilnius issue as an international problem. The author analyses the origins of the Polish-Lithuanian conflict, the role of the struggle for Vilnius in the general context of the Polish-Lithuanian confrontation, and the origin and nature of Lithuanian nationalism. The article also examines historiographical perspectives on the seizure of Vilnius by the troops of the Polish general, L. Żeligowsky, and the international consequences of the violation of the Suwałki Agreement. The author pays special attention to the positions of western powers, the decision of the Conference of Ambassadors on March 15, 1923, and the mediation of the League of Nations in the territorial dispute between Lithuania and Poland. The article considers the existing historiographical concepts and evaluations of the role of the Soviet diplomacy in the Vilnius issue. The author identifies new trends in the contemporary historiography of the Vilnius problem.

  5. Radiofrequency elektromagnetic radiation dynamics in vilnius city

    OpenAIRE

    Staniulytė, Justė

    2017-01-01

    Aim of the study – evaluate radio frequency electromagnetic radiation energy flux density emitted by Vilnius city base stations in the years 2009 – 2012 and compare results with the Republic of Lithuania hygiene standards HN 80:2011 and HN 80:2015 provisions. Study materials and method. In this paper the UAB (Ltd.)”Akustinių tyrimų centras” prepared measurement protocols of radio engineering objects in Vilnius city were used. Data analysis was performed using the statistical package ”R” 3.4.0...

  6. Senasis Vilnius tautų istorinės sąmonės perspektyvose

    OpenAIRE

    Bumblauskas, Alfredas

    2000-01-01

    It can be firmly stated that Lithuania is a part of Central Europe/Central and Eastern Europe and that Vilnius is akin to Krakow and Lvov, Bratislava and Prague, Budapest and Cluj, Zagreb and Ljubljana. Vilnius can be considered a typical Central European city and capital. This serves as a firm basis for considering the phenomenology of Vilnius. It is the northernmost Catholic and Baroque city both in Central Europe and in Europe, in general. Therefore, the history of Vilnius is relevant for ...

  7. Municipal elections: Zuokas-led non-party coalition conquers Vilnius / Rokas M. Tracevskis

    Index Scriptorium Estoniae

    Tracevskis, Rokas M.

    2011-01-01

    27. veebruaril Leedus peetud kohalikel valimistel kogus enim hääli Leedu Sotsiaaldemokraatlik Partei. Praeguse Vilniuse linnapea Arturas Zuokase koalitsioon on saanud 12 kohta Vilniuse linnavolikogus

  8. Socio-spatial transformatioSocio-Spatial Transformations, Suburbanisation, and Voting Behaviour in the Vilnius Urban Regionns, suburbanisation, and voting behaviour in the Vilnius urban region (discussion paper)

    NARCIS (Netherlands)

    Ubareviciene, R.; Burneika, D.; Van Ham, M.

    2012-01-01

    This paper analyses the interrelationship between the process of suburbanization and a changing political and ethnic landscape in the Vilnius urban region. The region surrounding Vilnius city is dominated by Polish identity residents while those who suburbanise into the region are mainly ethnic

  9. The Potential of New Urbanism in Vilnius

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    Catherine Brown

    2011-04-01

    Full Text Available In the wake of post-Soviet privatization, Vilnius has embraced westernized models for growth and development. The city is changing rapidly in a backlash against Soviet planning practice and with an influx of funding from the European Union and private investment. City plans aim for sustainable growth and development while tackling the revitalization of Soviet-era residential districts and control of suburban sprawl. This paper examines how planning efforts in Vilnius can benefit from the principles of New Urbanism as the reach of these popular American planning fundamentals provide convenient remedies to challenges in the redeveloping city.Article in English

  10. Nongratalased Turus, Vilniuses, Riias

    Index Scriptorium Estoniae

    2000-01-01

    Academia Non Grata osales Turu Hyräryllista galeriis David Crawforthi kureeritud rahvusvahelisel festivalil "Realm of the senses - a city wide experiment", Leedus Vilniuse Draamateatris performancei-festivalil "Laboratoorium". 8. XI Riias Matti Milius ja Raul Meel pidasid loenguid akadeemias, ANG esitles installatsiooni "Kreee", R. Meel ja Leonhard Lapin avasid personaalnäituse Reuters House'is. Valgas esitas ANG performance'i "SoftPower".

  11. Socio-spatial transformations, suburbanisation, and voting behaviour in the Vilnius urban region

    NARCIS (Netherlands)

    Ubarevi?ien?, R.; Burneika, D.; Van Ham, M.

    2012-01-01

    This paper analyses the interrelationship between the process of suburbanisation and a changing political and ethnic landscape in the Vilnius urban region. The region sur-rounding Vilnius city is dominated by Polish identity residents while those who suburbanise into the region are mainly ethnic

  12. Vilnius mayor dragged into corruption scandal / Steven Paulikas

    Index Scriptorium Estoniae

    Paulikas, Steven

    2004-01-01

    Vilniuse linnapea Arturas Zuokase suhtes on algatatud kriminaalmenetlus, süüdistuseks koos korporatsiooni Rubicon juhi Andrius Janukonisega altkäemaksu pakkumine linnavolikogu liikmele Vilmantas Dremale linnapea valimiste eel

  13. Understanding enhanced tourist experiences through technology: a brief approach to the Vilnius case

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    Ilona Beliatskaya

    2017-11-01

    Full Text Available The present research investigates the notion of enhanced tourist experiences through technology shedding light on co-creation practices and empowerment of customers. Neuhofer and Buhalis (2013 introduced a novel concept of technology-enhanced tourist experiences by generating a joint comprehension of new era of experiences which conjoin the elements of experiences, co-creation and technology. Being one of rather promoting cities in online environment Vilnius represents an interesting case of successive adoption of smart technologies in order to enhance tourist experiences and facilitate customer empowerment in Vilnius tourism domain. This study aims to determine technology-enhanced tourist experiences in order to measure factors of customer empowerment on the example of international incoming tourists to Vilnius (Lithuania. The mix-methods approach (qualitative online content and functionality analysis and quantitative survey was justified as being the most appropriate for the purpose of this research with intention to find a basis for applying of technology-enhanced tourist experiences in Vilnius tourism marketplace. The paper concludes with the definition of current level of ICTs application to enhance tourist experience co-creation and a discussion of practical implications of technology-enhanced tourist experiences development.

  14. Reval Hotel Lietuva Vilniuses : Konstitucijos pr. 20 / Piret Lindpere

    Index Scriptorium Estoniae

    Lindpere, Piret, 1963-

    2004-01-01

    Vilniuse hotelli "Lietuva" renoveerimine. Arhitektuurse projekti koostaja Rootsi arhitektuuribüroo AB SWECO (arhitektid Aare Saks, Nils Palm. Sisekujundus: Vaikla Disain AS (Katrin ja Argo Vaikla, Liis Lindvere, Peeter Loo). Kommenteerivad Argo ja Katrin Vaikla. 3 ill

  15. Vil'njusskij vopros v mezhdunarodnyh otnoshenijah: istoriografija problemy [The Vilnius issue in international relations: the historiography of the problem

    Directory of Open Access Journals (Sweden)

    Mankevich Maria

    2012-01-01

    Full Text Available This article considers certain historiographical aspects of the Vilnius issue as an international problem. The author analyses the origins of the Polish-Lithuanian conflict, the role of the struggle for Vilnius in the general context of the Polish-Lithuanian confrontation, and the origin and nature of Lithuanian nationalism. The article also examines historiographical perspectives on the seizure of Vilnius by the troops of the Polish general, L. Żeligowsky, and the international consequences of the violation of the Suwałki Agreement. The author pays special attention to the positions of western powers, the decision of the Conference of Ambassadors on March 15, 1923, and the mediation of the League of Nations in the territorial dispute between Lithuania and Poland. The article considers the existing historiographical concepts and evaluations of the role of the Soviet diplomacy in the Vilnius issue. The author identifies new trends in the contemporary historiography of the Vilnius problem.

  16. Urban land use in Natura 2000 surrounding areas in Vilnius Region, Lithuania.

    Science.gov (United States)

    Pereira, Paulo; Misiūnė, Ieva; Depellegrin, Daniel

    2015-04-01

    Urban development is one of the major causes of land degradation and pressure on protected areas. (Hansen and DeFries, 2007; Salvati and Sabbi, 2011). The urban areas in the fringe of the protected areas are a source of pollutants considered a negative disturbance to the ecosystems services and biodiversity within the protected areas. The distance between urban and protected areas is decreasing and in the future it is estimated that 88% of the world protected areas will be affected by urban growth (McDonald et al., 2008). The surrounding or buffer areas, are lands adjacent to the Natura 2000 territories, which aim to reduce the human influence within the protected areas. Presently there is no common definition of buffer area it is not clear among stakeholders (Van Dasselaar, 2013). The objective of this work is to identify the urban land use in the Natura 2000 areas in Vilnius region, Lithuania. Data from Natura 2000 areas and urban land use (Corine Land Cover 2006) in Vilnius region were collected in the European Environmental Agency website (http://www.eea.europa.eu/). In the surroundings of each Natura 2000 site, we identified the urban land use at the distances of 500, 1000 and 1500 m. The Natura 2000 sites and the urban areas occupied a total of 13.2% and 3.4% of Vilnius region, respectively. However, the urban areas are very dispersed in the territory, especially in the surroundings of Vilnius, which since the end of the XX century is growing (Pereira et al., 2014). This can represent a major threat to Natura 2000 areas ecosystem services quality and biodiversity. Overall, urban areas occupied approximately 50 km2, in the buffer area of 500 m, 95 km2 in buffer area of 1000 m and 131 km2 in the buffer area of 1500 km2. This shows that Natura 2000 surrounding areas in Vilnius region are subjected to a high urban pressure. This is especially evident in the Vilnius city and is a consequence of the uncontrolled urban development. The lack of a clear legislation

  17. Characteristics of cardiovascular deaths in forensic medical cases in Budapest, Vilnius and Tallinn.

    Science.gov (United States)

    Törő, Klara; Väli, Marika; Lepik, Delia; Tuusov, Jana; Dunay, György; Marcsa, Boglarka; Pauliukevicius, Alvydas; Raudys, Romas; Caplinskiene, Marija

    2013-11-01

    Evaluation of the pathomorphological characteristics of cases involving natural and sudden cardiovascular death is essential for the determination of the cause of death. The main purpose of this study is to investigate sudden unexpected cardiovascular death and to study how different geographical climatic influences may affect cardiac mortality in three capitals: Budapest, Vilnius and Tallinn. There were 8482 (5753 male, 2729 female) cardiovascular deaths between 2005 and 2009. The highest rate was observed in the age group between 71 and 80 years (35.17%) and 51-60 years (24.45%). The highest number of cardiovascular deaths occur in January (805/9.49%) and December (770/9.07%). Seasonal distribution was observed, with winter prevalence in Tallinn (279/3.20%) and spring prevalence in Vilnius (760/8.90%). Though in Vilnius and Budapest a great number of deaths occurred in winter and spring, any correlation with other factors (e.g. age, gender, BAC) was not statistically significant. Based on our results we can conclude that environmental-geographical parameters may affect natural cardiovascular death. Examination of pathological patterns and predisposing environmental parameters may help to improve prevention strategies. Copyright © 2013. Published by Elsevier Ltd.

  18. Lichens and allied fungi of two Regional Parks in Vilnius area (Lithuania

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    Jurga Motiejūnaitė

    2013-12-01

    Full Text Available Two Regional Parks – Verkiai and Pavilniai are situated in Vilnius city area comprising territories both of the city itself and Vilnius district and are under strong anthropogenic influence. During the present study 172 species of lichens, lichenicolous and saprobic fungi were revealed in Verkiai RP and 92 species – in Pavilniai RP. Three lichen species – Absconditella pauxilla, Thelenella pertusariella (in Verkiai RP, Bacidia caligans (in Pavilniai RP and one saprobic fungus – Chaenothecopsis debilis (in Verkiai RP are reporded for the first time in Lithuania. Seven lichen species of Lithuanian Red Data Book were recorded, all of them only in Verkiai RP; this indicates less strong anthropogenic impact and better conditions for biodiversity in this Park.

  19. Vilnius court approves extradition of Yukos-related banker / Milda Seputyte

    Index Scriptorium Estoniae

    Seputyte, Milda

    2005-01-01

    Vilniuse ringkonnakohus otsutas Venemaale välja anda Igor Babenko, kes oli Jukose tütarettevõtte Menatep St. Peterburg Bank'i juht. Venemaa süüdistab Babenkot panga juhtimise ajal 333 miljoni rubla omastamises. Babenko arvates on Leedu võimud temast huvitatud seotuse tõttu Jukosega

  20. «Eastern Partnership» after the Vilnius Summit

    Directory of Open Access Journals (Sweden)

    Anna Chernova

    2014-01-01

    Full Text Available The third summit of EU's Eastern Partnership held in Vilnius in November 2013 became a real turning point in the development of this organization. And it didn't happen due to signing of the first EU Association Agreement of its kind with the partner states but due to a sudden turn of the largest and most important of them - Ukraine - to the Russia's rival integration project. By doing so Ukraine at least temporarily joined two of the other participating countries: Armenia and Belarus, the latter of which is already in the Custom Union. At the other pole of the Eastern Partnership there are Georgia and Moldavia which initialed the Association and Free Trade agreements with the EU in Vilnius. This widening gap within the Eastern Partnership attracted everybody's attention to the EU - Russia rivalry in the post-Soviet countries which is increasingly interpreted in terms of the clash of civilizations. In this article we'd rather touch upon some of the peculiarities of the Eastern Partnership itself and its participating countries which to a large extent predetermined such an outcome. Among them is the ambiguous legacy of the European Neighbourhood Policy, lack of membership perspective in the EU as well as the nature of societies and elites in these post-Soviet states.

  1. Classification of Metal-Deficient Dwarfs in the Vilnius Photometric System

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    Lazauskaitė R.

    2003-12-01

    Full Text Available Methods used for the quantitative classification of metal-deficient stars in the Vilnius photometric system are reviewed. We present a new calibration of absolute magnitudes for dwarfs and subdwarfs, based on Hipparcos parallaxes. The new classification scheme is applied to a sample of Population II visual binaries.

  2. Kuidas suulise tõlke tudengid Vilniuses õppereisil käisid / Eero Loonurm

    Index Scriptorium Estoniae

    Loonurm, Eero

    2009-01-01

    Tallinna Ülikooli tõlkekoolituskeskus pakkus teise kursuse suulise tõlke eriala tudengitele ühe toreda praktikavõimaluse - kahepäevase õppereisi Vilniuse Ülikooli, kus toimus tõlkekonverents „Interpreting in the 21st Century“

  3. Incidence and direct hospitalisation costs of hip fractures in Vilnius, capital of Lithuania, in 2010

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    Tamulaitiene Marija

    2012-07-01

    Full Text Available Abstract Background Few epidemiological data on hip fractures were previously available in Lithuania. The aim of this study was to estimate the incidence and hospital costs of hip fractures in Vilnius in 2010. Methods Data were collected from the medical charts of all patients admitted to hospitals in Vilnius (population, 548,835 due to new low-energy trauma hip fracture, during 2010. The estimated costs included ambulance transportation and continuous hospitalisation immediately after a fracture, which are covered by the Lithuanian healthcare system. Results The incidence of new low-energy trauma hip fractures was 252 (308 women and 160 men per 100,000 inhabitants of Vilnius aged 50-years or more. There was an exponential increase in the incidence with increasing age. The overall estimated cost of hip fractures in Vilnius was 1,114,292 EUR for the year 2010. The greatest part of the expenditure was accounted for by fractures in individuals aged 65-years and over. The mean cost per case was 2,526.74 EUR, and cost varied depending on the treatment type. Hip replacement did not affect the overall mean costs of hip fracture. The majority of costs were incurred for acute (53% and long-term care (35% hospital stays, while medical rehabilitation accounted for only 12% of the overall cost. The costs of hip fracture were somewhat lower than those found in other European countries. Conclusion The data on incidence and costs of hip fractures will help to assess the importance of interventions to reduce the number of fractures and associated costs.

  4. Integrated photometry of globular star clusters in the Vilnius system

    International Nuclear Information System (INIS)

    Zdanavichyus, K.V.

    1983-01-01

    Integrated colour indices in the Vilnius photometric system and newly determined colour excesses Esub(B-V) for 39 globular clusters are presented. It is shown that the coincidence of integrated spectral types are not a sufficient criterion for the identity of intrinsic colour indices of globular clusters. Relation of integrated colour indices with the slope of the giant branch S and with the horizontal branch morphological type D is investigated. Integrated colour indices of clusters with a blue horizontal branch show no correlation with either D or S. The increase of colour indices of the clusters of types D >= 4 correlates with the distribution of stars along the horizontal branch. Integrated photometry of globular star clusters in the Vilnius multicoloured photometric system permits to determine their colour excesses from some Q diagrams and normal colour index. Integral normal colour indexes and Q parameters for I globular star clusters of the Mironov group display small changes as compared to clusters of group 2. Colour indexes among star clusters having only red horizontal branches (D=7) change most considerably

  5. Madoff Debacle Hits Colleges and Raises Questions about Trustee Conflicts

    Science.gov (United States)

    Fain, Paul

    2009-01-01

    Several colleges and universities lost millions in the alleged $50-billion Ponzi scheme run by the Wall Street trader Bernard L. Madoff. The losses include institutions' endowment holdings in hedge funds that were invested with Madoff as well as hits taken by supporting foundations and donors. Several foundations that have been active in higher…

  6. Education of radiation safety specialists at Faculty of Medicine of Vilnius University

    International Nuclear Information System (INIS)

    Urbelis, A.; Surkiene, G.

    2004-01-01

    Vilnius University is the first institution of higher education in Lithuania that began to teach students on radiation safety. The special course of radiation hygiene was delivered to students in 1962-1992. In 1992 it was introduced residency of radiation hygiene and graduated students qualified for title of radiation hygiene specialist. The residency lasted one year and included six cycles: fundamentals of nuclear physics, statistics and noninfectious epidemiology, radiobiology, radiological research methods, controls of radiation safety and hygienic analysis of radiation safety. From 1994 Vilnius University has been educating and training professionals of public health. The specialists of radiation safety aren't been training as isolated branch. All courses is divided into two parts. The first one is included into bachelor, the second part - into master study. The bachelor study consists of 2 credits (16 hours for lectures and 32 hours for practical studies). The future bachelors study introduction of radiation safety, elements of nuclear physics, dose limit values, fundamentals of radiological protection, natural radiation. The master study consists of 2 credits (8 hours for lectures and 48 hours for practical studies). The future masters study specific problems of radiation safety in medicine and industry, the safety problems of nuclear power - stations, the problems of radioactive wastes, radiation biology, radiation risk. Radiation safety study model in Faculty of medicine of Vilnius University differs from study model in most European countries as it makes great play of radiation safety while usual model includes radiation safety as insignificant part of environmental health. (author)

  7. Kanada helilooja Ted Dawsoniga Pärnu orelifestivalilt Kristoferi festivalile Vilniuses / Sirje Normet

    Index Scriptorium Estoniae

    Normet, Sirje

    2006-01-01

    Kanada heliloojast Ted Dawsonist, sidemetsest Eestiga, tema vokaaltsükli "Andres Ehin Cycle" esiettekandest Pärnu orelifestivalil ja klaverikontserdi "Wisteria" Euroopa esiettekandest Vilniuses toimunud ning 28. augustil lõppenud kirikumuusika festivali "St Christophoruse Festival" lõppkontserdil. Klaverikontserdi esitasid Aleksandra Juozapenaite-Eesmaa ja festivali kammerorkester Donatas Katkuse juhatusel

  8. Lithuania's first visa from 1990 on exhibit in the Vilnius airport / Rokas M. Tracevskis

    Index Scriptorium Estoniae

    Tracevskis, Rokas M.

    2010-01-01

    The Economisti ajakirjanik Edward Lucas, kellele väljastati esimene Leedu Vabariigi viisa numbriga 0001, andis selle viisaga passi Leedu välisministeeriumi muuseumile üle. 2011. aasta jooksul eksponeeritakse seda Vilniuse lennujaamas. Edward Lucase arvamusi Leedu poliitikast

  9. The Map of Vilnius Graffiti as an Indicator of Social Urban Change: the Case Study of Naujininkai Neighborhood

    Directory of Open Access Journals (Sweden)

    Veronika Urbonaitė-Barkauskienė

    2014-05-01

    Full Text Available This article, theoretically based on socio-spatial concepts of Lefebvre, de Certeau and their further interpreta - tions at the New Urban Sociology school (by Gottdiener, Zukin and others, examines the spread of graffiti in the urban space of Vilnius, the change of the local graffiti map during the years 2010–2013 and the possible social implications of the spotted modification of urban landscape. The qualitative research of Vilnius graffiti – which is understood both as an urban practice and an illicit urban inscription – and the case of Naujininkai neighborhood in particular, is based on data obtained from 1 in-depth interviews with experienced graffiti artists, 2 observation of graffiti in public space and 3 visual urban ethnography. Naujininkai neighborhood was attributed by local graffiti writers to the urban periphery in Vilnius graffiti map in 2010. However in 2010–2013 the visual development of urban landscape in Naujininkai indicates the trend, bringing the neigh- borhood a little closer to the urban core.

  10. Spatial Development Modeling Methodology Application Possibilities in Vilnius

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    Lina Panavaitė

    2017-05-01

    Full Text Available In order to control the continued development of high-rise buildings and their irreversible visual impact on the overall silhouette of the city, the great cities of the world introduced new methodological principles to city’s spatial development models. These methodologies and spatial planning guidelines are focused not only on the controlled development of high-rise buildings, but on the spatial modelling of the whole city by defining main development criteria and estimating possible consequences. Vilnius city is no exception, however the re-establishment of independence of Lithuania caused uncontrolled urbanization process, so most of the city development regulations emerged as a consequence of unmanaged processes of investors’ expectations legalization. The importance of consistent urban fabric as well as conservation and representation of city’s most important objects gained attention only when an actual threat of overshadowing them with new architecture along with unmanaged urbanization in the city center or urban sprawl at suburbia, caused by land-use projects, had emerged. Current Vilnius’ spatial planning documents clearly define urban structure and key development principles, however the definitions are relatively abstract, causing uniform building coverage requirements for territories with distinct qualities and simplifying planar designs which do not meet quality standards. The overall quality of urban architecture is not regulated. The article deals with current spatial modeling methods, their individual parts, principles, the criteria for quality assessment and their applicability in Vilnius. The text contains an outline of possible building coverage regulations and impact assessment criteria for new development. The article contains a compendium of requirements for high-quality spatial planning and building design.

  11. 'Hot' particles in the atmosphere (Vilnius, 1986)

    International Nuclear Information System (INIS)

    Lujanas, V.; Shpirkauskaite, N.

    1992-01-01

    After the Chernobyl accident in the atmosphere above Vilnius the alpha-and beta- 'hot' particles were discovered. The amount of particles and their size were measured by the alpha-radiography. After the exposition of nuclear plates the 'auroras' of the beta hot particles were of the size 0.37-22.2 μm. The change in time of the beta- 'hot' particles amount in the ground level air from the 25th of April to the 9th of May, 1986 was given. The amount of this particles deposited in the adult man respiratory tract was calculated. The energy of the discovered 8 'hot' alpha-particles ranged from 4.2 to 6.6 MeV. All the samples in which alpha- 'hot' particles found were taken in anticyclone conditions. (author). 1 tab., 1 ref

  12. Muusikamaailm : 15. ooperifestival Wexfordis. Tshellopidu algas Frankfurdis. Vilniuse "Gaida" lõppes eile. Konkursilt Besanqonis. Ernest Bour lahkunud / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2001-01-01

    15. ooperifestivalist Wexfordis. Frankfurdis toimunud Kronbergi tshellofestivali pidulikust avakontserdist. Vilniuse uue muusika festivalist "Gaida". Konkursilt Besanqonis. Suri nimekas prantsuse dirigent Ernest Bour

  13. Vilnius district heating pilot project. Final report. Annex 1-14

    International Nuclear Information System (INIS)

    1995-03-01

    The present energy scenario model is based on the SYSTEM ROERNET energy planning module and includes the energy flows from the energy source to the consumer for space heating and domestic hot water. The energy sources are: District heating of City based on CHP or/and heat-only production. District heating of Naujoji Vilnia based on heat-only production. Local boilers using natural gas or heavy fuel oil. Stoves using kerosene, coke or wood. (Electricity panel might be included, but this has not been the case in the actual analyses). The calculations of the energy model results in estimation of: Annual heat production, especially simulation of the plant production for district heating system with the possibility of integrated pooled operation by giving an order of priority to each plant based on the efficiency of the plant. Annual fuel consumption and the fuel costs for the society. Annual electricity production and its value to the society. Annual operation and maintenance costs including costs connected with consumption of electricity for district heating purposes. The total annual investments due to the set of options applied in the scenario in question. Savings in plant investments if less production capacity is necessary in scenarios where the heat demand is decreasing. The flue gas emissions from the heat and CHP production in the Vilnius area are estimated by CO 2 , SO 3 , NO x and particulates. These emissions are not reduced by the possible savings of electricity production of a reference power-only plant outside Vilnius. (EG)

  14. Ethno-Political effects of suburbanization in the Vilnius urban region : An analysis of voting behavior

    NARCIS (Netherlands)

    Ubareviciene, R.; Burneika, D.; Van Ham, M.

    2015-01-01

    We use electoral data to analyze the ethno-political consequences that may arise from the fact that the region surrounding the city of Vilnius is dominated by residents with a Polish identity, while those who move to the suburbs are mainly ethnic Lithuanians. In the suburban ring we found increasing

  15. A New Empirical Metallicity Calibration for Vilnius Photometry

    Directory of Open Access Journals (Sweden)

    Bartašiūtė S.

    2013-12-01

    Full Text Available We present a new calibration of the seven-color Vilnius system in terms of [Fe/H], applicable to F–M stars in the metallicity range −2.8 ≤[Fe/H]≤ +0.5. We employ a purely empirical approach, based on ~1000 calibrating stars with high-resolution spectroscopic abundance determinations. It is shown that the color index P–Y is the best choice for a most accurate and sensitive abundance indicator for both dwarf and giant stars. Using it, [Fe/H] values can be determined with an accuracy of ±0.12 dex for stars of solar and mildly subsolar metallicity and ±0.17 dex for stars with [Fe/H] < −1. The new calibration is a significant improvement over the previous one used to date.

  16. Virtual street-crossing performance in persons with multiple sclerosis: Feasibility and task performance characteristics.

    Science.gov (United States)

    Stratton, M E; Pilutti, L A; Crowell, J A; Kaczmarski, H; Motl, R W

    2017-01-02

    Multiple sclerosis (MS) is a neurological disease that commonly results in physical and cognitive dysfunction. Accordingly, MS might impact the ability to safely cross the street. The purpose of this study was to examine the feasibility of a simulated street-crossing task in persons with MS and to determine differences in street-crossing performance between persons with MS and non-MS controls. 26 participants with MS (median Expanded Disability Status Scale [EDSS] score = 3.5) and 19 controls completed 40 trials of a virtual street-crossing task. There were 2 crossing conditions (i.e., no distraction and phone conversation), and participants performed 20 trials per condition. Participants were instructed that the goal of the task was to cross the street successfully (i.e., without being hit be a vehicle). The primary outcome was task feasibility, assessed as completion and adverse events. Secondary outcomes were measures of street-crossing performance. Overall, the simulated street-crossing task was feasible (i.e., 90% completion, no adverse events) in participants with MS. Participants with MS waited longer and were less attentive to traffic before entering the street compared with controls (all P .05). A virtual street-crossing task is feasible for studying street-crossing behavior in persons with mild MS and most individuals with moderate MS. Virtual street-crossing performance is impaired in persons with MS compared to controls; however, persons with MS do not appear to be more vulnerable to a distracting condition. The virtual reality environment presents a safe and useful setting for understanding pedestrian behavior in persons with MS.

  17. RESEARCH INTO THE READING PROCESS OF OF THE ACADEMIC COMMUNITY OF THE OLD VILNIUS UNIVERSITY: ASPECTS OF HISTORIOGRAPHY

    Directory of Open Access Journals (Sweden)

    Krakyte, Asta

    2006-12-01

    Full Text Available The article provides a general overview of the research into the reading process of the academic community of Vilnius University in 1579–1832 derived from significant research in librarianship andbook science. It presents sources and strategies to reveal the multifaceted relations existing between literature, the reader, priorities, the environment, results, etc. This article also analyzes works in humanities and social sciences with significantly reliable data related to particular aspects of the issue.After investigating works of Lithuanian and Polish scientists M. Brensztejn, L. Piechnik, M. Birziska, L. Vladimirovas, P. Rabikauskas, D. Kuolys, etc., and comparing their deductions, it was observed that reading at Vilnius University in 1579–1832 was influenced by programs of sciences and official regulations of the Jesuit order no less than by local conditions. It is important to emphasize the remarkable influence of the characteristic classical model of education, applied at the University since 1579 and based on the learning of Latin, Greek and Hebrew language. Some changes were made to the local system of education since the middle of the 18th century due to the influence of the Piar order, but Jesuit authority directed the institution until 1832. Referred articles show that the process of education in Vilnius University was intended to promote a high level of maturity of the reader. During the process of learning new languages, students went through different stages of reading, improving their skills by interpretation and analysis. This was further cultivated in disputations, theatre performances and promoted by creating new texts, especially occasional publications. This process is reflected in numerous publications and manuscripts written by professors and students. Data accumulated in referred articles show that the usage of literature by academic community was influenced by books collated by University Library and traditional

  18. The effect of road and environmental characteristics on pedestrian hit-and-run accidents in Ghana.

    Science.gov (United States)

    Aidoo, Eric Nimako; Amoh-Gyimah, Richard; Ackaah, Williams

    2013-04-01

    The number of pedestrians who have died as a result of being hit by vehicles has increased in recent years, in addition to vehicle passenger deaths. Many pedestrians who were involved in road traffic accident died as a result of the driver leaving the pedestrian who was struck unattended at the scene of the accident. This paper seeks to determine the effect of road and environmental characteristics on pedestrian hit-and-run accidents in Ghana. Using pedestrian accident data extracted from the National Road Traffic Accident Database at the Building and Road Research Institute (BRRI) of the Council for Scientific and Industrial Research (CSIR), Ghana, a binary logit model was employed in the analysis. The results from the estimated model indicate that fatal accidents, unclear weather, nighttime conditions, and straight and flat road sections without medians and junctions significantly increase the likelihood that the vehicle driver will leave the scene after hitting a pedestrian. Thus, integrating median separation and speed humps into road design and construction and installing street lights will help to curb the problem of pedestrian hit-and-run accidents in Ghana. Copyright © 2012 Elsevier Ltd. All rights reserved.

  19. A post-mortem of the Vilnius Summit: not yet a 'Thessaloniki moment' for the Eastern Partnership

    OpenAIRE

    Kostanyan, Hrant; Blockmans, Steven

    2013-01-01

    In assessing the third Eastern Partnership (EaP) Summit at Vilnius on November 28-29th, this CEPS Commentary concludes that the event fell far short of its initial ambition to define the geopolitical finalité of EU-EaP relations by projecting a path towards future accession to the EU for Armenia, Azerbaijan, Belarus, Georgia, Moldova and Ukraine.

  20. 42 CFR 495.344 - Approval of the State Medicaid HIT plan, the HIT PAPD and update, the HIT IAPD and update, and...

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Approval of the State Medicaid HIT plan, the HIT PAPD and update, the HIT IAPD and update, and the annual HIT IAPD. 495.344 Section 495.344 Public... Requirements Specific to the Medicaid Program § 495.344 Approval of the State Medicaid HIT plan, the HIT PAPD...

  1. Street outreach with no streets.

    Science.gov (United States)

    Self, Bruce; Peters, Heather

    2005-01-01

    A street nurse position in the rural and small-town interior of British Columbia has been addressing the needs of street-involved or otherwise marginalized client populations by bringing healthcare services to wherever those clients are, rather than waiting for the clients to seek care. The primary reason for a street outreach approach is that marginalized populations face a variety of barriers to accessing traditional healthcare services--barriers such as homelessness, mental health problems, criminal involvement, lack of transportation, lack of ability to pay for prescriptions, lack of specialized or knowledgeable providers and provider discrimination. In the rural street nurse program, the target population includes the usual street nurse populations of illegal drug users and sex trade workers, which are more hidden in small communities than in larger urban centres, creating the community denial that is a barrier to healthcare access. Yet another barrier is the co-locaton of services common in small communities, where public health clinics might share a building with police services, making marginalized clients reluctant to attend clinics. The rural street nurse collaborates with public health nurses and other care providers (mental health workers, social workers, etc) with collegial advice and support, making and receiving referrals, and generally assisting one another--the street nurse through his rapport with the marginalized individuals and the others with their specialized knowledge. Rural street services are delivered whereverthe clientsfeel comfortable: a school, a drop-in centre, a mall, a youth centre or simplythe street. Services provided include sexually transmitted infection testing, chlamydia treatments, pregnancy testing emergency contraception pills and assistance with filling out forms for financial support. Accordingly, the street nurse's truck is equipped as a mobile treatment centre and office, with a cellphone and a stock of testing and

  2. Mental hygiene movement as a (r)evolutionary trend in public health in interwar Kaunas and Vilnius from 1918 to 1939.

    Science.gov (United States)

    Žalnora, Aistis; Miežutavičiūtė, Vitalija

    2016-01-01

    The health care system of the interwar period is distinguished by its revolutionary attempts to overcome social diseases and social hardships in general. In the researches published after the Second World War, different and in some cases even contradicting ideas on mental hygiene and eugenics were mixed together and were associated - almost exclusively - with the Nazi's racist ideology, totalitarian, or authoritarian regimes. The assessments of social-medical policy of the interwar period in the Baltic region also became rather one-sided. Felder's recent study (1) gives the impression that changes in psychiatry in Lithuania were caused by the Nazi's eugenics as a single agent. However, there were other factors. One of the most significant ones was the mental hygiene movement that will be discussed in this paper. In this research we used descriptive and comparative methods. After the First World War, the problem of treatment of the mentally ill was a medical and a social issue that required a completely new approach both in Lithuania and in Vilnius. The most notable manifestation of such a new attitude in psychiatry was a mental hygiene movement. University scientists in Vilnius and Kaunas were discussing issues of mental hygiene. The mental hygiene movement of the early 20th century played an important role in the later development in psychiatry and medical sciences. The ideas published by the medical doctors in Kaunas and Vilnius were partly characteristic of the interwar period, although some of them went far ahead of their times.

  3. Mapping optimal areas of ecosystem services potential in Vilnius (Lithuania)

    Science.gov (United States)

    Pereira, Paulo; Depellegrin, Daniel; Misiune, Ieva; Cerda, Artemi

    2016-04-01

    Maps are fundamental to understand the spatial pattern of natural and human impacts on the landscape (Brevik et al., 2016; Lavado Contador et al., 2009; Pereira et al., 2010a,b). Urban areas are subjected to an intense human pressure (Beniston et al., 2015), contributing to the degradation of the ecosystems, reducing their capacity to provide services in quality and quantity (Requier-Desjardins et al., 2011; Zhang et al., 2011). Environments that can provide a high number and quality of ecosystem services (ES) must be identified and managed correctly, since are spaces that can mitigate the impacts of human settlements and improve their quality. thus is of major importance have identify the areas that can provide better ES (Deppelegrin and Pereira, 2015). The aim of this work is to identify areas with high ES potential in Vilnius city. Here, we identified a total of 4 different land uses, agricultural areas (32.48%), water bodies (1.46%), forest and semi-natural (31.91%) areas and artificial surfaces (34.16%). CORINE land cover 2006 was used as base information to classify ES potential. The assessment of each land cover potential was carried out using expert assessment. Each land use type was ranked from 0 (no potential) to 5 (High potential). In this work the sum of total regulating, providing and cultural ES were assessed. The areas with optimal ES were the ones with the sum of all ranks equal or higher than the 3rd Quartil of each distribution. After identifying these areas, data was mapped using ArcGIS software. The results showed that on average Vilnius city has a higher potential for regulating services (20.35±15.92), followed by cultural (14.43±8.81) and providing (14.26±8.87). There was a significant correlation among the different type of services. Regulating vs cultural (0.92, p<0.001), regulating vs providing (0.72, p<0.001) and providing vs cultural (0.65, p<0.001). The results of Morans I autocorrelation index showed that regulating (Z-score: 10

  4. MANAGING CHANGE IN ACADEMIC LIBRARY: THE CASE OF VILNIUS UNIVERSITY LIBRARY

    Directory of Open Access Journals (Sweden)

    Marija Prokopčik

    2014-04-01

    Full Text Available ABSTRACTPurpose: The main objective of this article is to ascertain some most significant fields of the academic library activities, which have (or could have an impact on strengthening the library’s role as a partner in academic community, as well as to perform assessment of Vilnius University Library (thereinafter VUL capacities in order to see what kind of current or future activities performed by the library may contribute to the building-up of such role in Vilnius University (thereinafter VU community.Methodology/approach: Analysis of LIS professional literature of the latter five years reveals the key trends in development of academic libraries, their innovative change and challenges – partnerships of open access, managing of research data; research support; research assessment, Library scientific research, as well as allows to perform situation analysis of one particular library in order to see if and at what scale these identified trends can be traced in VUL.Results: It was established that VUL contributes to the idea and practical implementation of open access, collaborates with VU and Lithuania’s academic community in the projects of research data management, takes an active part in carrying out bibliometric research, helps to form a range of research support services, promotes the Library’s scholarly research and contributes to formation of the institution’s research potential.Research limitation: This article focuses on analysis of one academic library (VUL and its activities. Such issues like studies support, library as a space for communication, professional assistance in research events organization, improvement of information and media literacy were deliberately not covered.Originality/practical implications: Identification of common trends and measures of their practical implementation in one particular institution may be useful for other libraries planning the strategy of change and (or implementing selected solutions.

  5. 77 FR 32639 - HIT Standards Committee and HIT Policy Committee; Call for Nominations

    Science.gov (United States)

    2012-06-01

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee and HIT Policy Committee; Call for... Health Information Technology Policy Committee (HITPC). Name of Committees: HIT Standards Committee and HIT Policy Committee. General Function of the Committees: The HITSC is charged to provide...

  6. CCD photometry in the Vilnius photometric systems. II. Analysis of a region in Lyra

    International Nuclear Information System (INIS)

    Smriglio, F.; Dasgupta, A.K.; Boyle, R.P.; Straizys, V.; Janulis, R.

    1991-01-01

    Two-dimensional classification of 216 stars down to 17 mag based on their seven color photoelectric and CCD photometry in the Vilnius system is presented. Except for normal stars, several subdwarfs, metal-deficient giants, and stars of other peculiarities are suspected. Interstellar extinction is determined for normal stars in two areas north and south of globular cluster M56, as well as for a 1 square degree area around M56. The mean value of A v outside the galactic dust layer is ∼ 0.75 mag

  7. Hit Parade

    DEFF Research Database (Denmark)

    Backe, Hans-Joachim

    2017-01-01

    Daniel Cermak-Sassenrath, Max Alexander Wrighton, Hans-Joachim Backe. Hit Parade. Installation. Kulturnatten 2017, ITU, Copenhagen, DK, Oct 13, 2017.......Daniel Cermak-Sassenrath, Max Alexander Wrighton, Hans-Joachim Backe. Hit Parade. Installation. Kulturnatten 2017, ITU, Copenhagen, DK, Oct 13, 2017....

  8. Hit Parade

    DEFF Research Database (Denmark)

    Cermak, Daniel; Wrighton, Max Alexander; Backe, Hans-Joachim

    2016-01-01

    Daniel Cermak-Sassenrath, Max Alexander Wrighton, Hans-Joachim Backe. Hit Parade. Installation. Demo Night, ITU, Copenhagen, DK, Oct 5, 2016.......Daniel Cermak-Sassenrath, Max Alexander Wrighton, Hans-Joachim Backe. Hit Parade. Installation. Demo Night, ITU, Copenhagen, DK, Oct 5, 2016....

  9. NIMROD Simulations of the HIT-SI and HIT-SI3 Devices

    Science.gov (United States)

    Morgan, Kyle; Jarboe, Tom; Hossack, Aaron; Chandra, Rian; Everson, Chris

    2017-10-01

    The Helicity Injected Torus with Steady Inductive helicity injection (HIT-SI) experiment uses a set of inductively driven helicity injectors to apply non-axisymmetric current drive on the edge of the plasma, driving an axisymmetric spheromak equilibrium in a central confinement volume. Significant improvements have been made to extended MHD modeling of HIT-SI, with both the resolution of disagreement at high injector frequencies in HIT-SI in addition to successes with the new upgraded HIT-SI3 device. Previous numerical studies of HIT-SI, using a zero-beta eMHD model, focused on operations with a drive frequency of 14.5 kHz, and found reduced agreement with both the magnetic profile and current amplification at higher frequencies (30-70 kHz). HIT-SI3 has three helicity injectors which are able to operate with different mode structures of perturbations through the different relative temporal phasing of the injectors. Simulations that allow for pressure gradients have been performed in the parameter regimes of both devices using the NIMROD code and show improved agreement with experimental results, most notably capturing the observed Shafranov-shift due to increased beta observed at higher finj in HIT-SI and the variety of toroidal perturbation spectra available in HIT-SI3. This material is based upon work supported by the U.S. Department of Energy, Office of Science, Office of Fusion Energy Sciences under Award Number DE-FG02- 96ER54361.

  10. Hit Parade

    DEFF Research Database (Denmark)

    Cermak, Daniel; Wrighton, Max Alexander; Backe, Hans-Joachim

    2016-01-01

    Daniel Cermak-Sassenrath, Max Alexander Wrighton, Hans-Joachim Backe. Hit Parade. Installation. Kulturnatten 2016, Danish Science Ministry, Copenhagen, DK, Oct 14, 2016.......Daniel Cermak-Sassenrath, Max Alexander Wrighton, Hans-Joachim Backe. Hit Parade. Installation. Kulturnatten 2016, Danish Science Ministry, Copenhagen, DK, Oct 14, 2016....

  11. CCD photometry in the Vilnius photometric systems. II. Analysis of a region in Lyra

    Energy Technology Data Exchange (ETDEWEB)

    Smriglio, F.; Dasgupta, A.K. (Rome Univ. (IT). Ist. Astronomico); Nandy, K. (Royal Observatory, Edinburgh (UK)); Boyle, R.P. (Vatican Observatory, Rome (IT)); Straizys, V.; Janulis, R. (AN Litovskoj SSR, Vilnius (SU). Inst. Fiziki)

    1991-04-01

    Two-dimensional classification of 216 stars down to 17 mag based on their seven color photoelectric and CCD photometry in the Vilnius system is presented. Except for normal stars, several subdwarfs, metal-deficient giants, and stars of other peculiarities are suspected. Interstellar extinction is determined for normal stars in two areas north and south of globular cluster M56, as well as for a 1 square degree area around M56. The mean value of A{sub v} outside the galactic dust layer is {similar to} 0.75 mag.

  12. Post-hit dynamics of price limit hits in the Chinese stock markets

    Science.gov (United States)

    Wu, Ting; Wang, Yue; Li, Ming-Xia

    2017-01-01

    Price limit trading rules are useful to cool off traders short-term trading mania on individual stocks. The price dynamics approaching the limit boards are known as the magnet effect. However, the price dynamics after opening price limit hits are not well investigated. Here, we provide a detailed analysis on the price dynamics after the hits of up-limit or down-limit is open based on all A-share stocks traded in the Chinese stock markets. A "W" shape is found in the expected return, which reveals high probability of a continuous price limit hit on the following day. We also find that price dynamics after opening limit hits are dependent on the market trends. The time span of continuously hitting the price limit is found to an influence factor of the expected profit after the limit hit is open. Our analysis provides a better understanding of the price dynamics around the limit boards and contributes potential practical values for investors.

  13. Powered two-wheeler drivers' risk of hitting a pedestrian in towns.

    Science.gov (United States)

    Clabaux, Nicolas; Fournier, Jean-Yves; Michel, Jean-Emmanuel

    2014-12-01

    The risk of collision between pedestrians and powered two-wheelers is poorly understood today. The objective of this research is to determine the risk for powered two-wheeler drivers of hitting and injuring a pedestrian per kilometer driven in towns and to compare this risk with that run by four-wheeled vehicle drivers. Using the bodily injury accidents recorded by the police on nine roads in the city of Marseille in 2011 and a campaign of observations of powered two-wheeler traffic, we estimated the risk per kilometer driven by powered two-wheeler drivers of hitting a pedestrian and compared it with the risk run by four-wheeled vehicle drivers. The results show that the risk for powered two-wheeler drivers of hitting and injuring a pedestrian is significantly higher than the risk run by four-wheeled vehicle drivers. On the nine roads studied, it is on average 3.33 times higher (95% CI: 1.63; 6.78). Taking four more years into account made it possible to consolidate these results and to tighten the confidence interval. There does indeed seem to be problems in the interactions between pedestrians and powered two-wheeler users in urban traffic. These interaction problems lead to a higher risk of hitting and injuring a pedestrian for powered two-wheeler drivers than for four-wheeled vehicle drivers. The analysis of the police reports suggests that part of this increased risk comes from filtering maneuvers by powered two-wheelers. Possible countermeasures deal with the urban street layout. Measures consisting in reducing the width and the number of traffic lanes to a strict minimum and installing medians or pedestrian islands could be an effective way for the prevention of urban accidents between pedestrians and powered two-wheelers. Copyright © 2014 National Safety Council and Elsevier Ltd. All rights reserved.

  14. Eyewitness Identification Reforms: Are Suggestiveness-Induced Hits and Guesses True Hits?

    Science.gov (United States)

    Wells, Gary L; Steblay, Nancy K; Dysart, Jennifer E

    2012-05-01

    Research-based reforms for collecting eyewitness identification evidence (e.g., unbiased pre-lineup instructions, double-blind administration) have been proposed by psychologists and adopted in increasing numbers of jurisdictions across the United States. It is well known that reducing rates of mistaken identifications can also reduce accurate identification rates (hits). But the reforms are largely designed to reduce the suggestiveness of the procedures they are meant to replace. Accordingly, we argue that it is misleading to label any hits obtained because of suggestive procedures as "hits" and then saddle reforms with the charge that they reduce the rate of these illegitimate hits. Eyewitness identification evidence should be based solely on the independent memory of the witness, not aided by biased instructions, cues from lineup administrators, or the use of lineup fillers who make the suspect stand out. Failure to call out these hits as being illegitimate can give solace to those who are motivated to preserve the status quo. © The Author(s) 2012.

  15. CCD photometry in the Vilnius photometric system. I. region in Lyra

    International Nuclear Information System (INIS)

    Boyle, R.P.; Smriglio, F.; Straizys, V.

    1990-01-01

    Three-dimensional photometric classification can be made for stars measured in the Vilnius seven-color intermediate-band system, even if they are reddened by dust. Such classification is important for questions relating to the structure and evolution of our Galaxy. Presented here for general use is CCD photometry of 231 field stars in Lyra observed with the 0.9 meter telescope of Kitt Peak National Observatory. The measurements are of higher accuracy than those of a photographic study in the same direction in Lyra for which they can also be used for a deeper calibration of the photographic photometry. The data sets cover two small fields each about 31 arcmin 2 and are complete to 90% for all stars up to the faint limit of V = 17.5

  16. A fast online hit verification method for the single ion hit system at GSI

    International Nuclear Information System (INIS)

    Du, G.; Fischer, B.; Barberet, P.; Heiss, M.

    2006-01-01

    For a single ion hit facility built to irradiate specific targets inside biological cells, it is necessary to prove that the ions hit the selected targets reliably because the ion hits usually cannot be seen. That ability is traditionally tested either indirectly by aiming at pre-etched tracks in a nuclear track detector or directly by making the ion tracks inside cells visible using a stain coupled to special proteins produced in response to ion hits. However, both methods are time consuming and hits can be verified only after the experiment. This means that targeting errors in the experiment cannot be corrected during the experiment. Therefore, we have developed a fast online hit verification method that measures the targeting accuracy electronically with a spatial resolution of ±1 μm before cell irradiation takes place. (authors)

  17. RESEARCH INTO THE READING PROCESS OF OF THE ACADEMIC COMMUNITY OF THE OLD VILNIUS UNIVERSITY: ASPECTS OF HISTORIOGRAPHY

    OpenAIRE

    Krakyte, Asta

    2006-01-01

    The article provides a general overview of the research into the reading process of the academic community of Vilnius University in 1579–1832 derived from significant research in librarianship andbook science. It presents sources and strategies to reveal the multifaceted relations existing between literature, the reader, priorities, the environment, results, etc. This article also analyzes works in humanities and social sciences with significantly reliable data related to particular aspects o...

  18. Street children

    Directory of Open Access Journals (Sweden)

    Rončević Nevenka

    2013-01-01

    Full Text Available According to UNICEF, street child is any child under the age of 18 for whom the street has become home and/or source of income and which is not adequately protected or supervised by adult, responsible person. It has been estimated that there are between 100 and 150 million street children worldwide. Life and work on the street have long term and far-reaching consequences for development and health of these children. By living and working in the street, these children face the highest level of risk. Street children more often suffer from the acute illness, injuries, infection, especially gastrointestinal, acute respiratory infections and sexually transmitted diseases, inadequate nutrition, mental disorders, and drug abuse. They are more often victims of abuse, sexual exploitation, trafficking; they have higher rate of adolescent pregnancy than their peers from poor families. Street children and youth have higher rates of hospitalization and longer hospital stay due to seriousness of illness and delayed health care. Street children/youth are reluctant to seek health care, and when they try, they face many barriers. Street children are invisible to the state and their number in Serbia is unknown. Recently, some non­governmental organizations from Belgrade, Novi Sad and Nis have recognized this problem and tried to offer some help to street children, by opening drop­in centers, but this is not enough. To solve this problem, an engagement of the state and the whole community is necessary, and primary responsibility lies in health, social and educational sector. The best interests of the child must serve as a basic guideline in all activities aimed at improving health, quality of life and rights of children involved in the life and work in the street.

  19. Literatūrinio modernizmo preliudai XIX–XX amžių sandūros Vilniuje. Interjero kultūra ir privačiojo estetizmo tekstai | Preludes of Literary Modernism in Fin-de-siècle Vilnius: Interior Culture and Private Aestheticism Texts

    Directory of Open Access Journals (Sweden)

    Mindaugas Kvietkauskas

    2006-01-01

    Full Text Available The genesis prerequisites of the early literary Modernism appear in Vilnius during the last decade of the 19th century when the city encountered the first manifestations of the cultural consciousness of the modern liberal bourgeoisie. The first publicist texts of the independent Russian media (in 1898 the daily Северо-Западное Слово started circulating, and the architectural discourse of the city (the stylistics of Vilnius Land Bank colonies witness the classical liberal ideology of modernisation according to which the rational progress of civilisation harmoniously coincides with the individualistic values. The then still very scarce texts of Vilnius Russian and Polish literature and aesthetics were gradually moving away from the positivism of the 19th century towards the expression of modern individualism, bourgeois privacy, value liberalism, and aesthetic refinement. Vilnius literary texts generously depicted aesthetical interiors as private individual space, cultural shades from the dehumanising effect of technical progress (W. Benjamin. Aesthetical, closed interior turns into a semantically crucial space in the Vilnius novels Dwór w Haliniszkach (1903 and Z miłości (1903 by the Polish writer E. Jeleńska-Dmochowska. The private interior fantasies and the feeling of social isolation are clear features of mentality in novellas by the Vilnius Russian writer Yevgeny Shveder (Наброски и силуэты, 1904. The larger part of the early creative period of Kazys Puida should also be attributed to the melancholic discourse of the private aestheticism (Iš sermėgiaus krūtinės, 1906, Ruduo, 1906. The texts by the above authors sporadically demonstrated stylistic features of Parnassian and Decadent aestheticisms. The first collection of Polish poems published in the 20th century in Vilnius, the book Fale by Stanisława Szadurska (1906 also represented some melancholic features of the salon aesthetics and the classical

  20. Health Information Technology (HIT) Adaptation: Refocusing on the Journey to Successful HIT Implementation.

    Science.gov (United States)

    Yen, Po-Yin; McAlearney, Ann Scheck; Sieck, Cynthia J; Hefner, Jennifer L; Huerta, Timothy R

    2017-09-07

    In past years, policies and regulations required hospitals to implement advanced capabilities of certified electronic health records (EHRs) in order to receive financial incentives. This has led to accelerated implementation of health information technologies (HIT) in health care settings. However, measures commonly used to evaluate the success of HIT implementation, such as HIT adoption, technology acceptance, and clinical quality, fail to account for complex sociotechnical variability across contexts and the different trajectories within organizations because of different implementation plans and timelines. We propose a new focus, HIT adaptation, to illuminate factors that facilitate or hinder the connection between use of the EHR and improved quality of care as well as to explore the trajectory of changes in the HIT implementation journey as it is impacted by frequent system upgrades and optimizations. Future research should develop instruments to evaluate the progress of HIT adaptation in both its longitudinal design and its focus on adaptation progress rather than on one cross-sectional outcome, allowing for more generalizability and knowledge transfer. ©Po-Yin Yen, Ann Scheck McAlearney, Cynthia J Sieck, Jennifer L Hefner, Timothy R Huerta. Originally published in JMIR Medical Informatics (http://medinform.jmir.org), 07.09.2017.

  1. Polilingvali Vilniaus jaunimo raiška: socialinės tapatybės paieškos. Polylingual behaviour of Vilnius youth: Searching for social identity

    Directory of Open Access Journals (Sweden)

    Inga Vyšniauskienė

    2012-01-01

    Full Text Available The paper raises the problem of polilingual behaviour of Vilnius teenagers. The aim of this study is to reveal the frequency of linguistic features in the language of Vilnius teenagers of two age groups (13—14 and 15—17 as well as identify reasons for the informants’ polylingual behaviour. Extracts of spontaneous interactions from the corpus of the language of Vilnius youth have been chosen for the analysis. The results of the quantitative analysis have revealed that the elderly informants’ and younger boys’ polylingual behaviour is characterised by frequent, repetitive Russian features and nonrecurrent occurences of English features. The predominant use of English features in younger girls’ speech may imply that they have not yet mastered the Russian slang as well as point to their positive attitudes towards the English language. Within the framework of interactional sociolinguistics, the analysis of younger informants’ speech has revealed a link between English, German, Polish features and language play. Differently from the elderly teenagers, younger teenagers tend to change identities, e.g. an experienced player, an expert at love affairs, an adult who can evaluate youth language, via the play with English items. Russian items, which make a major part of slang in elderly teenagers’ speech, are used for sociopsychological purposes, as a means to display peer group identity. The study has revealed a varied polylingual production of Vilnius teenagers, which serves as a means of negotiating the social identity of a peer group member, creative and innovative teenager. ------ Straipsnyje keliama iki šiol Lietuvoje nenagrinėta jaunimo polilingvalaus elgesio problema. Tyrimo duomenis sudaro Vilniaus paauglių kalbos tekstynas, sukauptas renkant savanorių informantų įrašus ir atliekant etnografinius stebėjimus. Darbo tikslas – palyginti kitų kalbų elementų vartojimo dažnumą ir funkcijas jaunesniųjų (13–14 m. ir

  2. Urban streets

    NARCIS (Netherlands)

    Schönfeld, von Kim Carlotta; Bertolini, Luca

    2017-01-01

    Today's urban streets are usually planned for purposes of mobility: pedestrians, as well as a variety of vehicles such as cars, trucks, and sometimes bicycles, are usually factored into an urban street plan. However, urban streets are also increasingly recognized as public spaces, accommodating

  3. Dirty Hits

    OpenAIRE

    Clarke, Louise

    2010-01-01

    Issue 9 of the Saatchi Gallery Magazine: Art&Music is dedicated to Sex. The article Dirty Hits invited a cross-section of contemporary artists and musicians to answer: What makes a dirty hit? As one of the artists invited, I wrote an autobiographical piece to reveal how these fumbling, feral sexual experiences of my childhood landscape, along with irrational superstition and folk law inform my life and underpin my work. The article also included an artwork: Louise Clarke, Sip (2009)

  4. Quantum walks with infinite hitting times

    International Nuclear Information System (INIS)

    Krovi, Hari; Brun, Todd A.

    2006-01-01

    Hitting times are the average time it takes a walk to reach a given final vertex from a given starting vertex. The hitting time for a classical random walk on a connected graph will always be finite. We show that, by contrast, quantum walks can have infinite hitting times for some initial states. We seek criteria to determine if a given walk on a graph will have infinite hitting times, and find a sufficient condition, which for discrete time quantum walks is that the degeneracy of the evolution operator be greater than the degree of the graph. The set of initial states which give an infinite hitting time form a subspace. The phenomenon of infinite hitting times is in general a consequence of the symmetry of the graph and its automorphism group. Using the irreducible representations of the automorphism group, we derive conditions such that quantum walks defined on this graph must have infinite hitting times for some initial states. In the case of the discrete walk, if this condition is satisfied the walk will have infinite hitting times for any choice of a coin operator, and we give a class of graphs with infinite hitting times for any choice of coin. Hitting times are not very well defined for continuous time quantum walks, but we show that the idea of infinite hitting-time walks naturally extends to the continuous time case as well

  5. 77 FR 23250 - HIT Standards Committee; Schedule for the Assessment of HIT Policy Committee Recommendations

    Science.gov (United States)

    2012-04-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee; Schedule for the Assessment of HIT Policy Committee Recommendations AGENCY: Office of the National Coordinator for Health Information... 2009 mandates that the HIT Standards Committee develop a schedule for the assessment of policy...

  6. 76 FR 25355 - HIT Standards Committee; Schedule for the Assessment of HIT Policy Committee Recommendations

    Science.gov (United States)

    2011-05-04

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee; Schedule for the Assessment of HIT Policy Committee Recommendations AGENCY: Office of the National Coordinator for Health Information... 2009 mandates that the HIT Standards Committee develop a schedule for the assessment of policy...

  7. 78 FR 29134 - HIT Standards Committee; Schedule for the Assessment of HIT Policy Committee Recommendations

    Science.gov (United States)

    2013-05-17

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee; Schedule for the Assessment of HIT Policy Committee Recommendations AGENCY: Office of the National Coordinator for Health Information... 2009 mandates that the HIT Standards Committee develop a schedule for the assessment of policy...

  8. Statistical properties and pre-hit dynamics of price limit hits in the Chinese stock markets.

    Science.gov (United States)

    Wan, Yu-Lei; Xie, Wen-Jie; Gu, Gao-Feng; Jiang, Zhi-Qiang; Chen, Wei; Xiong, Xiong; Zhang, Wei; Zhou, Wei-Xing

    2015-01-01

    Price limit trading rules are adopted in some stock markets (especially emerging markets) trying to cool off traders' short-term trading mania on individual stocks and increase market efficiency. Under such a microstructure, stocks may hit their up-limits and down-limits from time to time. However, the behaviors of price limit hits are not well studied partially due to the fact that main stock markets such as the US markets and most European markets do not set price limits. Here, we perform detailed analyses of the high-frequency data of all A-share common stocks traded on the Shanghai Stock Exchange and the Shenzhen Stock Exchange from 2000 to 2011 to investigate the statistical properties of price limit hits and the dynamical evolution of several important financial variables before stock price hits its limits. We compare the properties of up-limit hits and down-limit hits. We also divide the whole period into three bullish periods and three bearish periods to unveil possible differences during bullish and bearish market states. To uncover the impacts of stock capitalization on price limit hits, we partition all stocks into six portfolios according to their capitalizations on different trading days. We find that the price limit trading rule has a cooling-off effect (object to the magnet effect), indicating that the rule takes effect in the Chinese stock markets. We find that price continuation is much more likely to occur than price reversal on the next trading day after a limit-hitting day, especially for down-limit hits, which has potential practical values for market practitioners.

  9. 46th Street pilot street lighting project.

    Science.gov (United States)

    2013-01-01

    Street lighting improvements provide an opportunity for governments to save money and to reduce their : environmental footprint. New energy-efficient technologies are being perfected that are more efficient than : standard high-pressure sodium street...

  10. Statistical Properties and Pre-Hit Dynamics of Price Limit Hits in the Chinese Stock Markets

    Science.gov (United States)

    Wan, Yu-Lei; Xie, Wen-Jie; Gu, Gao-Feng; Jiang, Zhi-Qiang; Chen, Wei; Xiong, Xiong; Zhang, Wei; Zhou, Wei-Xing

    2015-01-01

    Price limit trading rules are adopted in some stock markets (especially emerging markets) trying to cool off traders’ short-term trading mania on individual stocks and increase market efficiency. Under such a microstructure, stocks may hit their up-limits and down-limits from time to time. However, the behaviors of price limit hits are not well studied partially due to the fact that main stock markets such as the US markets and most European markets do not set price limits. Here, we perform detailed analyses of the high-frequency data of all A-share common stocks traded on the Shanghai Stock Exchange and the Shenzhen Stock Exchange from 2000 to 2011 to investigate the statistical properties of price limit hits and the dynamical evolution of several important financial variables before stock price hits its limits. We compare the properties of up-limit hits and down-limit hits. We also divide the whole period into three bullish periods and three bearish periods to unveil possible differences during bullish and bearish market states. To uncover the impacts of stock capitalization on price limit hits, we partition all stocks into six portfolios according to their capitalizations on different trading days. We find that the price limit trading rule has a cooling-off effect (object to the magnet effect), indicating that the rule takes effect in the Chinese stock markets. We find that price continuation is much more likely to occur than price reversal on the next trading day after a limit-hitting day, especially for down-limit hits, which has potential practical values for market practitioners. PMID:25874716

  11. Developing Health Information Technology (HIT) Programs and HIT Curriculum: The Southern Polytechnic State University Experience

    Science.gov (United States)

    Zhang, Chi; Reichgelt, Han; Rutherfoord, Rebecca H.; Wang, Andy Ju An

    2014-01-01

    Health Information Technology (HIT) professionals are in increasing demand as healthcare providers need help in the adoption and meaningful use of Electronic Health Record (EHR) systems while the HIT industry needs workforce skilled in HIT and EHR development. To respond to this increasing demand, the School of Computing and Software Engineering…

  12. [Sharing and distrusting: street merchants' view of children in street situations].

    Science.gov (United States)

    Sánchez-Suárez, Diana M; Giraldo-Puerta, Alexandra; Giraldo-Pineda, Álvaro; Forero-Pulido, Constanza

    2016-06-01

    Objective To understand the meanings, through the description of experiences that street merchants have of their interactions with children in a street situation in downtown of Medellin in 2013. Methodology Qualitative investigation with ethnographic approach. Observations were made in the zone at different times of the day. Twelve interviews with street merchants were held in their work places. Records were kept in a field journal. Results The street merchants and children in street situations share the same space. Both groups try to survive and their relationship is mediated by the trust-distrust that is established between them. The coexistence generates ambivalent feelings. For the street merchants, children in street situations are the result of abandonment by the family, the state and society. They live in a hard world in which they are exposed to a series of risks that they must face. Conclusion The interaction between street merchants and children in street situations is good to the extent that conflicts are avoided, establishing norms of coexistence. The element that determines this relationship is trust-distrust. In trust, strong affective ties are generated, considering each other family. Distrust generates a preventative attitude.

  13. True-3D accentuating of grids and streets in urban topographic maps enhances human object location memory.

    Directory of Open Access Journals (Sweden)

    Dennis Edler

    Full Text Available Cognitive representations of learned map information are subject to systematic distortion errors. Map elements that divide a map surface into regions, such as content-related linear symbols (e.g. streets, rivers, railway systems or additional artificial layers (coordinate grids, provide an orientation pattern that can help users to reduce distortions in their mental representations. In recent years, the television industry has started to establish True-3D (autostereoscopic displays as mass media. These modern displays make it possible to watch dynamic and static images including depth illusions without additional devices, such as 3D glasses. In these images, visual details can be distributed over different positions along the depth axis. Some empirical studies of vision research provided first evidence that 3D stereoscopic content attracts higher attention and is processed faster. So far, the impact of True-3D accentuating has not yet been explored concerning spatial memory tasks and cartography. This paper reports the results of two empirical studies that focus on investigations whether True-3D accentuating of artificial, regular overlaying line features (i.e. grids and content-related, irregular line features (i.e. highways and main streets in official urban topographic maps (scale 1/10,000 further improves human object location memory performance. The memory performance is measured as both the percentage of correctly recalled object locations (hit rate and the mean distances of correctly recalled objects (spatial accuracy. It is shown that the True-3D accentuating of grids (depth offset: 5 cm significantly enhances the spatial accuracy of recalled map object locations, whereas the True-3D emphasis of streets significantly improves the hit rate of recalled map object locations. These results show the potential of True-3D displays for an improvement of the cognitive representation of learned cartographic information.

  14. Street as Public Space - Measuring Street Life of Kuala Lumpur

    Science.gov (United States)

    Sulaiman, Normah; Ayu Abdullah, Yusfida; Hamdan, Hazlina

    2017-10-01

    Kuala Lumpur has envisioning in becoming World Class City by the year 2020. Essential elements of form and function of the urban environment are streets. Streets showcase the community and connect people. It’s one of the most comfortable social environment that provides aesthetical and interaction pleasure for everyone. Classified as main shopping streets in the local Kuala Lumpur urban design guidelines, Jalan Masjid India (JMI) has its uniqueness of shopping experience and social interaction. This conceptual paper will study the physical and cultural characteristics of the street that will generate the street character by mapping its original characters. The findings will focus on strengthening the methodology applied to promote improvements in evaluating it as a great public space. Results will also contribute to understanding the overall site context, the street connectivity, and urban dynamics. This paper is part of a larger study that addresses on transforming the sociability of public space.

  15. Multiple-hit parameter estimation in monolithic detectors.

    Science.gov (United States)

    Hunter, William C J; Barrett, Harrison H; Lewellen, Tom K; Miyaoka, Robert S

    2013-02-01

    We examine a maximum-a-posteriori method for estimating the primary interaction position of gamma rays with multiple interaction sites (hits) in a monolithic detector. In assessing the performance of a multiple-hit estimator over that of a conventional one-hit estimator, we consider a few different detector and readout configurations of a 50-mm-wide square cerium-doped lutetium oxyorthosilicate block. For this study, we use simulated data from SCOUT, a Monte-Carlo tool for photon tracking and modeling scintillation- camera output. With this tool, we determine estimate bias and variance for a multiple-hit estimator and compare these with similar metrics for a one-hit maximum-likelihood estimator, which assumes full energy deposition in one hit. We also examine the effect of event filtering on these metrics; for this purpose, we use a likelihood threshold to reject signals that are not likely to have been produced under the assumed likelihood model. Depending on detector design, we observe a 1%-12% improvement of intrinsic resolution for a 1-or-2-hit estimator as compared with a 1-hit estimator. We also observe improved differentiation of photopeak events using a 1-or-2-hit estimator as compared with the 1-hit estimator; more than 6% of photopeak events that were rejected by likelihood filtering for the 1-hit estimator were accurately identified as photopeak events and positioned without loss of resolution by a 1-or-2-hit estimator; for PET, this equates to at least a 12% improvement in coincidence-detection efficiency with likelihood filtering applied.

  16. Simple street tree sampling

    Science.gov (United States)

    David J. Nowak; Jeffrey T. Walton; James Baldwin; Jerry. Bond

    2015-01-01

    Information on street trees is critical for management of this important resource. Sampling of street tree populations provides an efficient means to obtain street tree population information. Long-term repeat measures of street tree samples supply additional information on street tree changes and can be used to report damages from catastrophic events. Analyses of...

  17. Violence in the Street, Violence of the Street

    DEFF Research Database (Denmark)

    Heinskou, Marie Bruvik; Liebst, Lasse Suonperä

    While in his early and general theory of interaction rituals Randall Collins emphasised that social situations are both ’symbolic’ and ’material’, the latter dimension is largely absent from Collins’ theory of violence(Collins 2004; 1993: 214). Compared with criminology’s more recent situational...... studies of violence, it is noticeable that the analytical success of these studies is closely linked with understanding street violence as a spatial-situational phenomenon (Clarke 1997; Eck & Weisburd 1995; Bragand & Weisburd; 2010; Wikström et al. 2012; Sampson et al. 1997). In light of evidence...... for the spatial concentration of street violence, this paper takes its point of departure in a large study of Street Violence among youth in Copenhagen, Denmark (combining quantitative data from filed police reports (N = 501), data from CCTV (N=100) and qualitative analysis of selected cases of street violence...

  18. [GEOLOGICAL OVERVIEW OF THE VILNIUS REGION BY J. E. GILIBERT (1741-1814), THE FIRST PROFESSOR OF NATURAL HISTORY AT THE UNIVERSITY OF VILNIUS].

    Science.gov (United States)

    Tarkowski, Radosław

    2015-01-01

    In 1775-1783, Jean-Emmanuel Gilibert (1741-1814) stayed in Respublica Poloniae to oranize a veterinary school, the Royal Botanic Garden and the Royal School of Physicians in Grodno, and since 1781 he worked in Vilnius as Professor of Natural History at the Principal School of the Grand Duchy of Lithuania. Little is known about his work conducted in Lithuania in the field of geology and earth sciences. The author has decided, on the basis of Gilibert's publications and analysis of the literature (works of J. Garbowska and P. Daszkiewicz and others), to present his teaching and research activities in this field. In Grodno, Gilibert looked after and multiplied the collections of the natural history cabinet at the Royal School of Physicians, renowned for its rich mineralogical and fossil collections watched and admired by, among others, King Stanisław August, J. Bernoulli (1744-1807) and M. Patrin (1742-1815) who mentions the amber rosary with a different species of insects preserved in each bead. Gilibert's tours around Lithuania were the opportunity to enlarge the geological collections and to adapt them to the needs of the school. He also appreciated the importance of ordinary specimens representing the geology of the area. These specimens not only enriched the natural history cabinet, but also defined the way of working and collecting. Ha was the first to found and gather fossil animals from near Grodno. The signs of mineralogical and geological interests of Gilibert can be found in the works of other authors of that epoch (L. Viteta (1736-1809) and J. Bernoulli). In Vilnius, Gilibert conducted a one year-long full lecture on natural history (zoology, botany and mineralogy). In his lectures on mineralogy, he presented not only the systematics, but also emphasized the usefulness of minerals in medicine, for the production of ornamental items and in different sectors of the economy. He adapted the process of teaching to the needs of practical life, based on

  19. The SVT Hit Buffer

    International Nuclear Information System (INIS)

    Belforte, S.; Dell'Orso, M.; Donati, S.

    1996-01-01

    The Hit Buffer is part of the Silicon Vertex Tracker, a trigger processor dedicated to the reconstruction of particle trajectories in the Silicon Vertex Detector and the Central Tracking Chamber of the Collider Detector at Fermilab. The Hit Buffer is a high speed data-traffic node, where thousands of words are received in arbitrary order and simultaneously organized in an internal structured data base, to be later promptly retrieved and delivered in response to specific requests. The Hit Buffer is capable of processing data at a rate of 25 MHz, thanks to the use of special fast devices like Cache-Tag RAMs and high performance Erasable Programmable Logic Devices from the XILINX XC7300 family

  20. Heparin-independent, PF4-dependent binding of HIT antibodies to platelets: implications for HIT pathogenesis.

    Science.gov (United States)

    Padmanabhan, Anand; Jones, Curtis G; Bougie, Daniel W; Curtis, Brian R; McFarland, Janice G; Wang, Demin; Aster, Richard H

    2015-01-01

    Antibodies specific for platelet factor 4 (PF4)/heparin complexes are the hallmark of heparin-induced thrombocytopenia and thrombosis (HIT), but many antibody-positive patients have normal platelet counts. The basis for this is not fully understood, but it is believed that antibodies testing positive in the serotonin release assay (SRA) are the most likely to cause disease. We addressed this issue by characterizing PF4-dependent binding of HIT antibodies to intact platelets and found that most antibodies testing positive in the SRA, but none of those testing negative, bind to and activate platelets when PF4 is present without any requirement for heparin (P HIT antibodies recognize PF4 in a complex with heparin, only a subset of these antibodies recognize more subtle epitopes induced in PF4 when it binds to CS, the major platelet glycosaminoglycan. Antibodies having this property could explain "delayed HIT" seen in some individuals after discontinuation of heparin and the high risk for thrombosis that persists for weeks in patients recovered from HIT. © 2015 by The American Society of Hematology.

  1. Safety of street: The role of street design

    Science.gov (United States)

    Rashid, Suhaila Abdul; Wahab, Mohammad Hussaini; Rani, Wan Nurul Mardiah Wan Mohd.; Ismail, Syuhaida

    2017-10-01

    Living in the cities poses many challenges for the vulnerable group of user especially women where they are exposed to many issues related to safety. With the changing of lifestyle and demands, women are expected to play multiple roles in the society and working is one of the tasks. When women are expected to be working as men do, they are no longer occupied at one place. Women nowadays travel on a daily basis and being in the streets is one of the important activities. With the influx of diverse group of people into the country, our streets are dominated by different types of people from different background. Due to these factors, there are possibilities of challenges and threats for users especially women. Therefore, city spaces especially the street become an important public realm for women. The design of the street should be able to make women feel safe as these are the public space where they spend time getting to and from work. The way women perceived their environment might be different from men especially when they fear of crime. Perception of safety will affect the quality of life where fear is an important psychological factor in human life. Living in fear will restrict human's freedom. Therefore, this study aimed to explore women's perception of safety in the streets of Kuala Lumpur. The study adopted a mixed-method approach of qualitative and quantitative in order to understand the safety perception among women that will later establish the relationship between built environment and human psychology. 120 respondents were selected randomly around Jalan Benteng, Jalan Tun Perak, Jalan Melaka and Jalan Melayu. Questionnaire survey forms were distributed and structured observation was conducted at interval period at these streets to examined and assess women's behavior. Finding shows that fear does affect women's perception and physical design of the streets are important in affecting their behavior.

  2. POLICY EVALUATION OF RESTRUCTURING STREET VENDORS IN SURAKARTA CITY (Study of Street Vendors in Monument Park Banjarsari and Street Vendors in Manahan Stadium

    Directory of Open Access Journals (Sweden)

    Frahlevi Prajasari

    2015-08-01

    Full Text Available This study examined the policy evaluation of restructuring street vendors in Surakarta city. Street vendors represent the economic actors in the informal sector of urban economic activity. The government of City/District usually removes these street vendors by disguising this activity behind the reason of structuring, . The study used descriptive research with a qualitative approach. The relocation of street vendors in Surakarta City is orderly and smooth without violence which may impact badly on physic and material because the government of Surakarta City, especially Surakarta Mayor, uses persuasive approach. Notoharjo Market is a relocation place for street vendors at Banjarsari Monument Park. In the beginning, Notoharjo Market is crowded with buyers but current days, street vendors who occupy Notoharjo Market complain about lack of buyers. The lack of buyers at Notoharjo Market is because the facilities previously provided by the government of Surakarta City are not well maintained. The government of Surakarta City must listening all complains of street vendors for the smoothness and orderliness of trading activity of street vendors. Not only listening, but the government of Surakarta City also gives appropriate and best solution to street vendors such that street vendors feel comfort in selling and their income is better than before.

  3. Street Children and Employment Opportunities

    International Nuclear Information System (INIS)

    Enos, H.N.; Njoka, M.

    1999-01-01

    Although there is a general realization that there are 'people' in the streets, we often take the phenomenon for granted probably because we wake up and go home only to come to the streets the following morning and still find the people. This situation is however changing with the emergence of 'birth' and increase of street children as we begin to take into consideration the category of people to be routinely found on the streets. The phrase 'street children' refer to the children below the statutory adult age living on or found on the streets. These children derive their livelihood from the streets. While the children on the streets may have a 'home' to go to, the latter are an integral part of the street having nowhere to retire to at the end of the day. The street children live in abject poverty and are exposed to many risks. They suffer from malnutrition and deficiency diseases due to low and poor nutrition intake. The street girls get trapped in teenage prostitution quite early in life. Of concern are the issues related to the working street children. Many street children engage in collecting and selling waste paper, bottles and plastics. They are referred to as 'chokora' because of their work of turning garbage upside down as they look for something useful. Unfortunately they have to sell these wastes to powerful forces including people who underpay and harrass them

  4. How I treat double-hit lymphoma.

    Science.gov (United States)

    Friedberg, Jonathan W

    2017-08-03

    The 2016 revision of the World Health Organization (WHO) classification for lymphoma has included a new category of lymphoma, separate from diffuse large B-cell lymphoma, termed high-grade B-cell lymphoma with translocations involving myc and bcl-2 or bcl-6 . These lymphomas, which occur in hit lymphomas (or triple-hit lymphomas if all 3 rearrangements are present). It is important to differentiate these lymphomas from the larger group of double-expressor lymphomas, which have increased expression of MYC and BCL-2 and/or BCL-6 by immunohistochemistry, by using variable cutoff percentages to define positivity. Patients with double-hit lymphomas have a poor prognosis when treated with standard chemoimmunotherapy and have increased risk of central nervous system involvement and progression. Double-hit lymphomas may arise as a consequence of the transformation of the underlying indolent lymphoma. There are no published prospective trials in double-hit lymphoma, however retrospective studies strongly suggest that aggressive induction regimens may confer a superior outcome. In this article, I review my approach to the evaluation and treatment of double-hit lymphoma, with an eye toward future clinical trials incorporating rational targeted agents into the therapeutic armamentarium. © 2017 by The American Society of Hematology.

  5. Street children and political violence: a socio-demographic analysis of street children in Rwanda.

    Science.gov (United States)

    Veale, Angela; Donà, Giorgia

    2003-03-01

    The aims were: (1) to examine the profile of African street children and to assess the link between street children in Africa and political violence; (2) to undertake a systematic examination of causal factors of street children in postgenocide Rwanda; and (3) to situate this analysis in the context of the socio-cultural and political impact of the genocide on Rwandan communities. Observational mapping examined the profile and activities of Rwandan street children. Structured interviews were carried out with 290 children in four regional towns to obtain information on socio-demographic, familial, educational background, causal factors surrounding street life involvement, psychological well-being, and relationship to the street. Focus group discussions and key informant interviews examined the relationship between street children and the broader Rwandan society. Street children in Rwanda were predominantly adolescent boys, almost half of whom were homeless (42%), with a high proportion of orphaned children or children who had lost at least one parent. Two variables predicted homelessness: child's guardian and reason for being in street. Qualitative accounts of children conveyed the impact of death of family members, repatriation, imprisonment of parents, and poverty on their lives. The analysis highlighted the need for community based support for children in alternative guardianship care and for policies to support the reintegration of male youths in postconflict welfare strategies as prevention strategies for street migration.

  6. Statistics of hits to bone cell nuclei

    International Nuclear Information System (INIS)

    Kruglikov, I.L.; Polig, E.; Jee, W.S.S.

    1993-01-01

    The statistics of hits to the nuclei of bone cells irradiated from alpha sources labeling bone tissue is described. It is shown that the law of remodeling of a bone structural unit (BSU), which describes the distribution of quiescence periodes of this unit, affects the statistics of hits. It the irradiation of bone cells occurs during the whole cell cycle, the mean number of hits is independent of the law of remodeling. In this case the variance of hits has the minimum value for constant quiescence periods of BSUs (deterministic remodeling) and the maximum value for exponentially distributed quiescence periods (random remodeling). For the first generation of bone cells, i.e. for the cells which existed at the moment of the uptake of the nuclide, the mean number of hits depends on the law of remodeling. For random remodeling the mean number is equal to the mean value for the complete remodeling cycle. For deterministic remodeling the mean is only half this value. For the first generation of bone cells, changing the law of remodeling from random to deterministic increases the probability of no hits to the nuclei of bone cells. For the same mean value of hits, the difference does not exceed 13.3% of the total number of cells. For the subsequent generations of bone cells, such a change of the law of remodeling decreases the probability of no hits up to 20.4% of the total number of cells. (orig.)

  7. Adolescent Hopefulness in Tanzania: Street Youth, Former Street Youth, and School Youth

    Science.gov (United States)

    Nalkur, Priya G.

    2009-01-01

    This study compares hope in street youth, former street youth, and school youth (aged 12-18) in Tanzania. Responding to Snyder's hope theory, the author argues that not only personal agency but also the stability of living context (street, shelter, home) shapes hopefulness. Employing qualitative and quantitative analyses, the author presents a…

  8. Recent Improvements in the SHIELD-HIT Code

    DEFF Research Database (Denmark)

    Hansen, David Christoffer; Lühr, Armin Christian; Herrmann, Rochus

    2012-01-01

    Purpose: The SHIELD-HIT Monte Carlo particle transport code has previously been used to study a wide range of problems for heavy-ion treatment and has been benchmarked extensively against other Monte Carlo codes and experimental data. Here, an improved version of SHIELD-HIT is developed concentra......Purpose: The SHIELD-HIT Monte Carlo particle transport code has previously been used to study a wide range of problems for heavy-ion treatment and has been benchmarked extensively against other Monte Carlo codes and experimental data. Here, an improved version of SHIELD-HIT is developed...

  9. Nedley Depression Hit Hypothesis

    OpenAIRE

    Nedley, Neil; Ramirez, Francisco E.

    2014-01-01

    Depression is often diagnosed using the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5) criteria. We propose how certain lifestyle choices and non-modifiable factors can predict the development of depression. We identified 10 cause categories (hits or ?blows? to the brain) and theorize that four or more active hits could trigger a depression episode. Methods. A sample of 4271 participants from our community-based program (70% female; ages 17-94 years) was assessed ...

  10. Current insights into the laboratory diagnosis of HIT.

    Science.gov (United States)

    Bakchoul, T; Zöllner, H; Greinacher, A

    2014-06-01

    Heparin-induced thrombocytopenia (HIT) is an adverse drug reaction and prothrombotic disorder caused by immunization against platelet factor 4 (PF4) after complex formation with heparin or other polyanions. After antibody binding to PF4/heparin complexes, HIT antibodies are capable of intravascular platelet activation by cross-linking Fc gamma receptor IIa (FcγRIIa) on the platelet surface leading to a platelet count decrease and/or thrombosis. In contrast to most other immune-mediated disorders, the currently available laboratory tests for anti-PF4/heparin antibodies show a high sensitivity also for clinically irrelevant antibodies. This makes the diagnosis of HIT challenging and bears the risk to substantially overdiagnose HIT. The strength of the antigen assays for HIT is in ruling out HIT when the test is negative. Functional assays have a higher specificity for clinically relevant antibodies, but they are restricted to specialized laboratories. Currently, a Bayesian approach combining the clinical likelihood estimation for HIT with laboratory tests is the most appropriate approach to diagnose HIT. In this review, we give an overview on currently available diagnostic procedures and discuss their limitations. © 2014 John Wiley & Sons Ltd.

  11. Constructive Technology Assessment for HIT development

    DEFF Research Database (Denmark)

    Høstgaard, Anna Marie Balling; Bertelsen, Pernille; Petersen, Lone Stub

    2013-01-01

    Experience and time has shown a need for new evaluation methods for evaluating Health Information Technology (HIT), as summative evaluation methods fail to accommodate the rapid and constant changes in HIT over time and to involve end-users, which has been recognized as an important success facto...... during all the phases in the process. Thereby anumber of problems were prevented to occur later on.Thus, the CTA method and its framework are useful for evaluators and project-management in order to facilitate and support successful HIT development....

  12. Streets? Where We're Going, We Don't Need Streets

    Science.gov (United States)

    Bailey, J.

    2017-12-01

    In 2007 Google Street View started as a project to provide 360-degree imagery along streets, but in the decade since has evolved into a platform through which to explore everywhere from the slope of everest, to the middle of the Amazon rainforest to under the ocean. As camera technology has evolved it has also become a tool for ground truthing maps, and provided scientific observations, storytelling and education. The Google Street View "special collects" team has undertaken increasingly more challenging projects across 80+ countries and every continent. All of which culminated in possibly the most ambitious collection yet, the capture of Street View on board the International Space Station. Learn about the preparation and obstacles behind this and other special collects. Explore these datasets through both Google Earth and Google Expeditions VR, an educational tool to take students on virtual field trips using 360 degree imagery.

  13. Thermal Comfort Assessment in The Open Space in Bandung Case Study Dago Street and Riau Street

    Science.gov (United States)

    Sugangga, M.; Janesonia, K. I.; Illiyin, D. F.; Donny Koerniawan, M.

    2018-05-01

    Bandung’s temperature has been higher since last years. This phenomenon affects the level of thermal comfort in open space. One indicator that determines the thermal comfort level is the type of activity performed by the open space user. Riau Street and Dago Street are corridors that are often used by the people for strolling, jogging, shopping. Dago Street has special event every Sunday namely car free day. Both corridors have different orientation; Dago Street is North to South corridor while Riau Street’s is West to East. The goal of the study is to compare people’s perception of thermal comfort in both corridors. This research uses two methods, namely qualitative method and quantitative method. Based on the results of qualitative analysis found that the thermal conditions in Dago Street more comfortable than the Riau Street. The result of quantitative analysis found that the average PET (thermal comfort indices) value of Dago Street was at 27.5 °C PET and Riau Street 28.6 °C PET. Dago Street is considered more convenient because it has a lower PET value than Riau Street. The people perception of thermal comfort is very important to start the steps for designing the orientation of street in urban design.

  14. Potential reductions of street solids and phosphorus in urban watersheds from street cleaning, Cambridge, Massachusetts, 2009-11

    Science.gov (United States)

    Sorenson, Jason R.

    2013-01-01

    Material accumulating and washing off urban street surfaces and ultimately into stormwater drainage systems represents a substantial nonpoint source of solids, phosphorus, and other constituent loading to waterways in urban areas. Cost and lack of usable space limit the type and number of structural stormwater source controls available to municipalities and other public managers. Non-structural source controls such as street cleaning are commonly used by cities and towns for construction, maintenance and aesthetics, and may reduce contaminant loading to waterways. Effectiveness of street cleaning is highly variable and potential improvements to water quality are not fully understood. In 2009, the U.S. Geological Survey, in cooperation with the Massachusetts Department of Environmental Protection, the U.S. Environmental Protection Agency, and the city of Cambridge, Massachusetts, and initiated a study to better understand the physical and chemical nature of the organic and inorganic solid material on street surfaces, evaluate the performance of a street cleaner at removing street solids, and make use of the Source Loading and Management Model (SLAMM) to estimate potential reductions in solid and phosphorus loading to the lower Charles River from various street-cleaning technologies and frequencies. Average yield of material on streets collected between May and December 2010, was determined to be about 740 pounds per curb-mile on streets in multifamily land use and about 522 pounds per curb-mile on commercial land-use streets. At the end-of-winter in March 2011, about 2,609 and 4,788 pounds per curb-mile on average were collected from streets in multifamily and commercial land-use types, respectively. About 86 percent of the total street-solid yield from multifamily and commercial land-use streets was greater than or equal to 0.125 millimeters in diameter (or very fine sand). Observations of street-solid distribution across the entire street width indicated that as

  15. Simplified validation of borderline hits of database searches

    OpenAIRE

    Thomas, Henrik; Shevchenko, Andrej

    2008-01-01

    Along with unequivocal hits produced by matching multiple MS/MS spectra to database sequences, LC-MS/MS analysis often yields a large number of hits of borderline statistical confidence. To simplify their validation, we propose to use rapid de novo interpretation of all acquired MS/MS spectra and, with the help of a simple software tool, display the candidate sequences together with each database search hit. We demonstrate that comparing hit database sequences and independent de novo interpre...

  16. 78 FR 29135 - HIT Standards Committee Advisory Meeting

    Science.gov (United States)

    2013-05-17

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting AGENCY: Office of...: HIT Standards Committee. General Function of the Committee: To provide recommendations to the National... Federal Health IT Strategic Plan, and in accordance with policies developed by the HIT Policy Committee...

  17. Reduction of multiple hits in atom probe tomography

    International Nuclear Information System (INIS)

    Thuvander, Mattias; Kvist, Anders; Johnson, Lars J.S.; Weidow, Jonathan; Andrén, Hans-Olof

    2013-01-01

    The accuracy of compositional measurements using atom probe tomography is often reduced because some ions are not recorded when several ions hit the detector in close proximity to each other and within a very short time span. In some cases, for example in analysis of carbides, the multiple hits result in a preferential loss of certain elements, namely those elements that frequently field evaporate in bursts or as dissociating molecules. In this paper a method of reducing the effect of multiple hits is explored. A fine metal grid was mounted a few millimeters behind the local electrode, effectively functioning as a filter. This resulted in a decrease in the overall detection efficiency, from 37% to about 5%, but also in a decrease in the fraction of multiple hits. In an analysis of tungsten carbide the fraction of ions originating from multiple hits decreased from 46% to 10%. As a result, the measured carbon concentration increased from 48.2 at%to 49.8 at%, very close to the expected 50.0 at%. The characteristics of the multiple hits were compared for analyses with and without the grid filter. - Highlights: ► APT experiments have been performed with a reduced amount of multiple hits. ► The multiple hits were reduced by placing a grid behind the electrode. ► This resulted in improved carbon measurement of WC

  18. 42 CFR 495.340 - As-needed HIT PAPD update and as-needed HIT IAPD update requirements.

    Science.gov (United States)

    2010-10-01

    ... limited to any of the following: (a) A projected cost increase of $100,000 or more. (b) A schedule... implementation approach, or scope of activities beyond that approved in the HIT planning advance planning document or the HIT implementation advance planning document. (d) A change in implementation concept or a...

  19. On the Hitting Probability of Max-Stable Processes

    OpenAIRE

    Hofmann, Martin

    2012-01-01

    The probability that a max-stable process {\\eta} in C[0, 1] with identical marginal distribution function F hits x \\in R with 0 < F (x) < 1 is the hitting probability of x. We show that the hitting probability is always positive, unless the components of {\\eta} are completely dependent. Moreover, we consider the event that the paths of standard MSP hit some x \\in R twice and we give a sufficient condition for a positive probability of this event.

  20. Wall Street som kreationistisk forkynder

    DEFF Research Database (Denmark)

    Ekman, Susanne

    2016-01-01

    Artiklen gennemgår Karen Hos etnografi om Wall Street: "Liquidated: An ethnography of Wall Street" set i lyset af den offentlige debat vedrørende Goldman Sachs opkøb af Dong......Artiklen gennemgår Karen Hos etnografi om Wall Street: "Liquidated: An ethnography of Wall Street" set i lyset af den offentlige debat vedrørende Goldman Sachs opkøb af Dong...

  1. Implementation of a rapid HIT immunoassay at a university hospital - Retrospective analysis of HIT laboratory orders in patients with thrombocytopenia.

    Science.gov (United States)

    Black, Anne; Heimerl, Susanne; Oertli, Linnéa; Wilczek, Wolf; Greinacher, Andreas; Spannagl, Michael; Herr, Wolfgang; Hart, Christina

    2017-10-01

    Heparin-induced thrombocytopenia (HIT) is a rare cause of thrombocytopenia and a potentially life-threatening adverse drug reaction. Clinical overdiagnosis of HIT results in costly laboratory tests and anticoagulation. Criteria and algorithms for diagnosis are established, but their translation into clinical practice is still challenging. In a retrospective approach we studied all HIT related laboratory test requests within four years and evaluated data before (1st period, 24month) and after (2nd period, 24month) replacing particle gel immunoassay (PaGIA) and enzyme-linked immunosorbent assay (ELISA) by a chemiluminescent immunoassay (CLIA). HIT was confirmed by heparin-induced platelet activation (HIPA) test. Clinical pretest probability for HIT using an implemented simplified 4Ts score and platelet count were evaluated. Costs for laboratory tests and alternative anticoagulation were calculated. In 1850 patients with suspected HIT, 2327 laboratory orders were performed. In 87.2% of these orders an intermediate/high simplified 4Ts score was found. Thrombocytopenia was present in 87.1%. After replacing PaGIA and ELISA by CLIA the number of immunological and functional laboratory tests was reduced by 38.2%. The number of positive HIT immunoassays declined from 22.6% to 6.0%, while the number of positive HIPA tests among positive immunological tests increased by 19%. Altogether, acute HIT was confirmed in 59 patients. A decline in the use of alternative anticoagulants was observed in the 2nd period. Our study shows that in a university hospital setting HIT is well-known, but diagnosis requires a precise laboratory confirmation. Replacing PaGIA and ELISA by CLIA did not influence laboratory order behavior but results in reduced overall costs for laboratory diagnostics and alternative anticoagulation. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. RACE, CODE OF THE STREET, AND VIOLENT DELINQUENCY: A MULTILEVEL INVESTIGATION OF NEIGHBORHOOD STREET CULTURE AND INDIVIDUAL NORMS OF VIOLENCE*

    Science.gov (United States)

    Stewart, Eric A.; Simons, Ronald L.

    2011-01-01

    The study outlined in this article drew on Elijah Anderson’s (1999) code of the street perspective to examine the impact of neighborhood street culture on violent delinquency. Using data from more than 700 African American adolescents, we examined 1) whether neighborhood street culture predicts adolescent violence above and beyond an adolescent’s own street code values and 2) whether neighborhood street culture moderates individual-level street code values on adolescent violence. Consistent with Anderson’s hypotheses, neighborhood street culture significantly predicts violent delinquency independent of individual-level street code effects. Additionally, neighborhood street culture moderates individual-level street code values on violence in neighborhoods where the street culture is widespread. In particular, the effect of street code values on violence is enhanced in neighborhoods where the street culture is endorsed widely. PMID:21666759

  3. Novel HIT antibody detection method using Sonoclot® coagulation analyzer.

    Science.gov (United States)

    Wanaka, Keiko; Asada, Reiko; Miyashita, Kumiko; Kaneko, Makoto; Endo, Hirokazu; Yatomi, Yutaka

    2015-01-01

    Since heparin-induced thrombocytopenia (HIT), caused by the generation of antibodies against platelet factor 4 (PF4)/heparin complexes (HIT antibodies), may induce serious complications due to thrombosis, a prompt diagnosis is desirable. Functional tests with platelet activation to detect HIT antibodies are useful for diagnosis of HIT, in particular (14)C-selotonin release assay (SRA). However, they are complicated and so can be performed only in limited laboratories. We tested if a blood coagulation test using Sonoclot® analyzer can serve for the detection of HIT antibodies. A murine monoclonal antibody (HIT-MoAb) against PF4/heparin complexes was used as an alternative to human HIT antibodies. To the mixture of HIT-MoAb and heparin (0.5 U/mL, final), whole blood obtained from a healthy volunteer was added, and then the activated clotting time (ACT), clot rate (CR), and area under the curve (AUC) were measured with Sonoclot® analyzer for 30minutes. The HIT-MoAb (30 to 100μg/mL, final) concentration dependently suppressed the anticoagulation activity (prolongation of ACT and decrease of CR and AUC) of heparin. The suppression of anticoagulation effect of heparin by HIT-MoAb was demonstrated by measurements using Sonoclot® analyzer. This method may provide a new tool for screening of HIT antibodies. Copyright © 2014 Elsevier Ltd. All rights reserved.

  4. Simulating the impacts of on-street vehicle parking on traffic operations on urban streets using cellular automation

    Science.gov (United States)

    Chen, Jingxu; Li, Zhibin; Jiang, Hang; Zhu, Senlai; Wang, Wei

    2017-02-01

    In recent years, many bicycle lanes on urban streets are replaced with vehicle parking places. Spaces for bicycle riding are reduced, resulting in changes in bicycle and vehicle operational features. The objective of this study is to estimate the impacts of on-street parking on heterogeneous traffic operation on urban streets. A cellular automaton (CA) model is developed and calibrated to simulate bicycle lane-changing on streets with on-street parking. Two types of street segments with different bicycle lane width are considered. From the simulation, two types of conflicts between bicycles and vehicles are identified which are frictional conflicts and blocking conflicts. Factors affecting the frequency of conflicts are also identified. Based on the results, vehicle delay is estimated for various traffic situations considering the range of occupancy levels for on-street parking. Later, a numerical network example is analyzed to estimate the network impact of on-street parking on traffic assignment and operation. Findings of the study are helpful to policies and design regarding on-street vehicle parking to improve the efficiency of traffic operations.

  5. The validation of Huffaz Intelligence Test (HIT)

    Science.gov (United States)

    Rahim, Mohd Azrin Mohammad; Ahmad, Tahir; Awang, Siti Rahmah; Safar, Ajmain

    2017-08-01

    In general, a hafiz who can memorize the Quran has many specialties especially in respect to their academic performances. In this study, the theory of multiple intelligences introduced by Howard Gardner is embedded in a developed psychometric instrument, namely Huffaz Intelligence Test (HIT). This paper presents the validation and the reliability of HIT of some tahfiz students in Malaysia Islamic schools. A pilot study was conducted involving 87 huffaz who were randomly selected to answer the items in HIT. The analysis method used includes Partial Least Square (PLS) on reliability, convergence and discriminant validation. The study has validated nine intelligences. The findings also indicated that the composite reliabilities for the nine types of intelligences are greater than 0.8. Thus, the HIT is a valid and reliable instrument to measure the multiple intelligences among huffaz.

  6. MYC/BCL2/BCL6 triple hit lymphoma: a study of 40 patients with a comparison to MYC/BCL2 and MYC/BCL6 double hit lymphomas.

    Science.gov (United States)

    Huang, Wenting; Medeiros, L Jeffrey; Lin, Pei; Wang, Wei; Tang, Guilin; Khoury, Joseph; Konoplev, Sergej; Yin, C Cameron; Xu, Jie; Oki, Yasuhiro; Li, Shaoying

    2018-05-21

    High-grade B-cell lymphomas with MYC, BCL2, and BCL6 rearrangements (triple hit lymphoma) are uncommon. We studied the clinicopathologic features of 40 patients with triple hit lymphoma and compared them to 157 patients with MYC/BCL2 double hit lymphoma and 13 patients with MYC/BCL6 double hit lymphoma. The triple hit lymphoma group included 25 men and 15 women with a median age of 61 years (range, 34-85). Nine patients had a history of B-cell lymphoma. Histologically, 23 (58%) cases were diffuse large B-cell lymphoma and 17 cases had features of B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma. Most cases of triple hit lymphoma were positive for CD10 (100%), BCL2 (95%), BCL6 (82%), MYC (74%), and 71% with MYC and BCL2 coexpression. P53 was overexpressed in 29% of triple hit lymphoma cases. The clinicopathological features of triple hit lymphoma patients were similar to patients with MYC/BCL2 and MYC/BCL6 double hit lymphoma, except that triple hit lymphoma cases were more often CD10 positive compared with MYC/BCL6 double hit lymphoma (p hit lymphoma and double hit lymphoma and overall survival in triple hit lymphoma patients was 17.6 months, similar to the overall survival of patients with double hit lymphoma (p = 0.67). Patients with triple hit lymphoma showing P53 overexpression had significantly worse overall survival compared with those without P53 overexpression (p = 0.04). On the other hand, double expressor status and prior history of B-cell lymphoma did not correlate with overall survival. In conclusion, most patients with triple hit lymphoma have an aggressive clinical course and poor prognosis and these tumors have a germinal center B-cell immunophenotype, similar to patients with double hit lymphomas. P53 expression is a poor prognostic factor in patients with triple hit lymphoma.

  7. Street-art

    OpenAIRE

    Rybnikářová, Klára

    2009-01-01

    This thesis is concerned with the street-art and graffiti phenomenon. The theoretical research is focused on presenting the essence and character of this art style, while also watching it from socio-cultural point of view and observing it in context of art history. The theoretical study is followed by the didactical part of thesis, where I present possibilities of using the street-art theme in art education programs in the school setting. My thesis is concluded with a discussion of a practica...

  8. Citygml and the Streets of New York - a Proposal for Detailed Street Space Modelling

    Science.gov (United States)

    Beil, C.; Kolbe, T. H.

    2017-10-01

    Three-dimensional semantic city models are increasingly used for the analysis of large urban areas. Until now the focus has mostly been on buildings. Nonetheless many applications could also benefit from detailed models of public street space for further analysis. However, there are only few guidelines for representing roads within city models. Therefore, related standards dealing with street modelling are examined and discussed. Nearly all street representations are based on linear abstractions. However, there are many use cases that require or would benefit from the detailed geometrical and semantic representation of street space. A variety of potential applications for detailed street space models are presented. Subsequently, based on related standards as well as on user requirements, a concept for a CityGML-compliant representation of street space in multiple levels of detail is developed. In the course of this process, the CityGML Transportation model of the currently valid OGC standard CityGML2.0 is examined to discover possibilities for further developments. Moreover, a number of improvements are presented. Finally, based on open data sources, the proposed concept is implemented within a semantic 3D city model of New York City generating a detailed 3D street space model for the entire city. As a result, 11 thematic classes, such as roadbeds, sidewalks or traffic islands are generated and enriched with a large number of thematic attributes.

  9. Street Children as M arginal People: The Relationship between Life History and Social Networks on the Street

    OpenAIRE

    SUCHARITKUL, Juthathip

    2007-01-01

    This paper assumes that street children are victims of socioeconomic development policy. As a consequence of the street life experience, children are labeled as street children by society and their way of their life is different from ordinary children, thus pushing them to become marginalized people. The purpose of this paper is to examine the Street Children phenomenon, and especially to study the relationship between their life history and personal networks on the street. The focus is to...

  10. MAPCERN links to Google Street View

    CERN Multimedia

    Matilda Heron

    2015-01-01

    CERN’s online maps, MAPCERN, now have the added bonus of Google Street View, thanks to the new release of images of many CERN sites captured by Google.   New Street View images of CERN sites have been added to MAPCERN, see bottom-right-hand image in the screenshot above.   Google Street View, an integrated service of Google Maps introduced in 2007, links 360-degree panoramic photos into a virtual tour. CERN and Google began collaborating on this Street View project in 2010 and now these Street View images have been embedded into MAPCERN, accessible by clicking the “Street View” tab in MAPCERN’s bottom-right-hand window. If you need to locate a building at CERN, or plan an operation on some equipment, you can save time by using the Street View images to check out the area in advance. The CERN Meyrin site has been fully mapped, as well as the surfaces of the eight LHC points, BA2 and BA3. New Street View images of CERN, including the Pr...

  11. Allegheny County Street Centerlines

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — This dataset contains the locations of the street centerlines for vehicular and foot traffic in Allegheny County. Street Centerlines are classified as Primary Road,...

  12. Street Politics

    Directory of Open Access Journals (Sweden)

    Michael J. Shapiro

    2012-03-01

    Full Text Available I write from Prague, where, unlike in most urban formations, the main city street plays an iconic role; it references a history of political protest. However, before elaborating on the protest iconography of the Prague street, Vaclavske nam, I want to locate the ways in which the design of urban space is actualized in everyday life in the cities of the world. Three functions stand out; the first involves dwelling, the second seeing, and the third moving. With respect to the first function – dwelling – the design partitions and coordinates residential, commercial and leisure functions. At times these are organized to segregate different classes (Robert Moses’ redesign of much of New York stands out with respect to the segregation function. With respect to the second function – seeing – the design of urban space is allegiance-inspiring; it involves sight lines that afford urban dwellers and visitors views of iconic buildings and statues, which reference key founding moments in the past and/or authoritative political functions in the present (Here, L’Enfants design for Washington DC stands out as exemplary. Its manifest intention was to make the buildings housing executive, legislative and judicial functions visible from many vantage points. Rarely are the streets themselves iconic. Their dominant role is involved with the effectuation of movement. As for this third function: As Lewis Mumford famously points out, streets were once part of an asterisk design, radiating out from an exemplary, often spiritual center...

  13. Road and Street Centerlines, Street-The data set is a line feature consisting of 13948 line segments representing streets. It was created to maintain the location of city and county based streets., Published in 1989, Davis County Government.

    Data.gov (United States)

    NSGIC Local Govt | GIS Inventory — Road and Street Centerlines dataset current as of 1989. Street-The data set is a line feature consisting of 13948 line segments representing streets. It was created...

  14. Mean Streets: An analysis on street level pollution in NYC

    Science.gov (United States)

    Parker, G.

    2017-12-01

    The overarching objective of this study is to quantify the spatial and temporal variability in particulatematter concentration (PM 2.5) along crowded streets in New York City. Due to their fine size and lowdensity PM 2.5 stays longer in the atmosphere and could bypass human nose and throat and penetratedeep in to the lungs and even enter the circulatory system. PM 2.5 is a by-product of automobilecombustion and is a primary cause of respiratory malfunction in NYC. The study would monitor streetlevel concentration of PM2.5 across three different routes that witness significant pedestrian traffic;observations will be conducted along these three routes at different time periods. The study will use theAirBeam community air quality monitor. The monitor tracks PM 2.5 concentration along with GPS, airtemperature and relative humidity. The surface level concentration monitored by AirBeam will becompared with atmospheric concentration of PM 2.5 that are monitored at the NOAA CREST facility onCCNY campus. The lower atmospheric values will be correlated with street level values to assess thevalidity of using of lower atmospheric values to predict street level concentrations. The street levelconcentration will be compared to the air quality forecasted by the New York Department ofEnvironment Conservation to estimate its accuracy and applicability.

  15. Street art - vandalismus nebo umění?

    OpenAIRE

    Grabmüllerová, Eva

    2012-01-01

    The diploma thesis ‚Street Art - Vandalism or Art?' deals with a world-wide phenomenon of contemporary art. The thesis focuses on the characterization of street art and history of street art (its origin and development) and analyzes the difference between street art and graffiti. The thesis presents street art techniques as well as notable street artists. The thesis also observes street art scene in the Czech Republic and depicts features that street art has in common with other art movements...

  16. Personal and Familial Properties of Street Children--"Street Children: The Forgotten or Not Remembered Ones"

    Science.gov (United States)

    Özbas, Mehmet

    2015-01-01

    With this research it is aimed to determine the personal traits of Street Children depending on them and also the socio-economic variables of Street Children resulting from their families. For this main aim in the research process, it is provided to have communication directly with the parents of Street Children using one-to-one and face-to-face…

  17. Heavy metal contamination in surface runoff sediments of the urban area of Vilnius, Lithuania

    Directory of Open Access Journals (Sweden)

    Gytautas Ignatavičius

    2017-02-01

    Full Text Available Surface runoff from urbanized territories carries a wide range of pollutants. Sediments in untreated runoff from direct discharge stormwater systems significantly contribute to urban waterway pollution. In this study, heavy metal (Pb, Zn, Cu, Cr, Ba, As and Fe contamination in surface runoff sediments of the urban area of the city of Vilnius was investigated. The surface runoff sediment samples were collected from seven dischargers with the highest volume rate of water flow and concentrations of suspended solids. The geospatial analysis of the distribution of heavy metals shows that there are several active pollution sources supplying the dischargers with contaminated sediments. Most of these areas are located in the central part of the city and in old town with intense traffic. Principal components analysis and t-test results clearly depicted the significantly different chemical compositions of winter and autumn surface sediment samples. The sampling approach and assessment of results provide a useful tool to examine the contamination that is generated in urban areas, distinguish pollution sources and give a better understanding of the importance of permeable surfaces and green areas.

  18. Health information technology knowledge and skills needed by HIT employers.

    Science.gov (United States)

    Fenton, S H; Gongora-Ferraez, M J; Joost, E

    2012-01-01

    To evaluate the health information technology (HIT) workforce knowledge and skills needed by HIT employers. Statewide face-to-face and online focus groups of identified HIT employer groups in Austin, Brownsville, College Station, Dallas, El Paso, Houston, Lubbock, San Antonio, and webinars for rural health and nursing informatics. HIT employers reported needing an HIT workforce with diverse knowledge and skills ranging from basic to advanced, while covering information technology, privacy and security, clinical practice, needs assessment, contract negotiation, and many other areas. Consistent themes were that employees needed to be able to learn on the job and must possess the ability to think critically and problem solve. Many employers wanted persons with technical skills, yet also the knowledge and understanding of healthcare operations. The HIT employer focus groups provided valuable insight into employee skills needed in this fast-growing field. Additionally, this information will be utilized to develop a statewide HIT workforce needs assessment survey.

  19. The social world of street children : street children's peer friendship, group life and subculture in Addis Ababa, Ethiopia

    OpenAIRE

    Fikre, Kaleab

    2016-01-01

    This study attempts to explore the street children’s social world, focusing on their peer friendship, group life, and street subculture in Addis Ababa, Ethiopia. The study shows how street children’s peer friendship, street group, and subculture are part and parcel of children’s quest for survival in the street in the absence of guardians conventionally considered as responsible for the provision and protection of children. The main perspective of the study is grounded in the p...

  20. COMMON GROUNDS BETWEEN PRINTMAKING AND STREET ART

    Directory of Open Access Journals (Sweden)

    Burcak Balamber

    2016-09-01

    Full Text Available Graffiti movement, born as a result of an effort of the youth, who felt themselves socially excluded and alone, to show their existence and identities during the 1960s, expanded its scope owing to street based artists such as Keith Haring and Jean-Michel Basquiat entering to the galleries, and transformed into an artistic manner of expression having aesthetic concerns by adopting a more inclusive definition ‘street art’. During this transformation of street art,street artists experimented with various methods from many different disciplines and hence created works in a wide range of varieties in terms of plastic and artistic values. Among these disciplines, printmakinghastaken its own place in street artas a discipline thatdeeply influenced street artists.Printmaking has fascinated street artists and become a part of their production process, not only with its philosophy sharing common grounds with street art and advantages in terms of its tecnical practices but also its unique plastic and linear values.Thanks to the opportunities of printmaking, street art has succeeded creating a tremendous impression worldwide, and even positioned itself into today’s greatest museums/gallery halls. This article aims to show how and in what way printmaking has influenced street art being in a transformation since the 1960s, and to put an emphasis on theimportance of printmaking on today’s street art.

  1. A Two-Hit Model of Autism: Adolescence as the Second Hit

    Science.gov (United States)

    Picci, Giorgia; Scherf, K. Suzanne

    2015-01-01

    Adolescence brings dramatic changes in behavior and neural organization. Unfortunately, for some 30% of individuals with autism, there is marked decline in adaptive functioning during adolescence. We propose a two-hit model of autism. First, early perturbations in neural development function as a “first hit” that sets up a neural system that is “built to fail” in the face of a second hit. Second, the confluence of pubertal hormones, neural reorganization, and increasing social demands during adolescence provides the “second hit” that interferes with the ability to transition into adult social roles and levels of adaptive functioning. In support of this model, we review evidence about adolescent-specific neural and behavioral development in autism. We conclude with predictions and recommendations for empirical investigation about several domains in which developmental trajectories for individuals with autism may be uniquely deterred in adolescence. PMID:26609500

  2. Intelligent street lighting clustering

    NARCIS (Netherlands)

    Verhoeven, R.; Jovanovic, N.; Lukkien, J.J.

    2014-01-01

    The advances in dynamic street lighting introduce new functionality for control and maintenance of the street lighting infrastructure. Vital elements in this infrastructure are the powerful controlling devices that control separate groups of light poles and collect information from the system. For

  3. 75 FR 21629 - HIT Standards Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2010-04-26

    ... Technology; HIT Standards Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National... only. Name of Committees: HIT Standards Committee's Workgroups: Clinical Operations Vocabulary... developed by the HIT Policy Committee. Date and Time: The HIT Standards Committee Workgroups will hold the...

  4. 77 FR 66617 - HIT Policy and Standards Committees; Workgroup Application Database

    Science.gov (United States)

    2012-11-06

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy and Standards Committees; Workgroup Application... of New ONC HIT FACA Workgroup Application Database. The Office of the National Coordinator (ONC) has.... Name of Committees: HIT Standards Committee and HIT Policy Committee. General Function of the...

  5. 76 FR 46297 - HIT Standards Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2011-08-02

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee's Workgroup Meetings; Notice of... be open to the public via dial-in access only. Name of Committees: HIT Standards Committee's... developed by the HIT Policy Committee. Date and Time: The HIT Standards Committee Workgroups will hold the...

  6. StreetMekka - Ledelse af Københavns nye streetkulturhus

    OpenAIRE

    Gjelstrup, Mikkel

    2009-01-01

    Street culture is spreading out through the streets of Denmark and in the summer of 2009 the City of Copenhagen will open up an indoor street culture facility called StreetMekka. Moving street culture from its natural concrete habitat to a communal facility presents challenges. The City of Copenhagen has made official guideline for the StreetMekka facility to follow, but the free and self organized street culture is not an easy thing to keep within guidelines. This master thesis discusses fro...

  7. Road and Street Centerlines, StreetLabels-The data set is a text feature consisting of 6329 label points representing street names. It was created to show the names of city and county based streets., Published in 1989, Davis County Government.

    Data.gov (United States)

    NSGIC Local Govt | GIS Inventory — Road and Street Centerlines dataset current as of 1989. StreetLabels-The data set is a text feature consisting of 6329 label points representing street names. It was...

  8. Road and Street Centerlines - COUNTY_STREET_CENTERLINES_IDHS_IN: Street Centerlines Maintained by County Agencies in Indiana (Indiana Department of Homeland Security, Line Shapefile)

    Data.gov (United States)

    NSGIC State | GIS Inventory — COUNTY_STREET_CENTERLINES_IDHS_IN is a line feature class that contains street centerlines maintained by county agencies in Indiana, provided by personnel of Indiana...

  9. Hit-and-run, hit-and-stay, and commensal bacteria present different peptide content when viewed from the perspective of the T cell.

    Science.gov (United States)

    He, Lu; De Groot, Anne S; Bailey-Kellogg, Chris

    2015-11-27

    Different types of bacteria face different pressures from the immune system, with those that persist ("hit-and-stay") potentially having to adapt more in order to escape than those prone to short-lived infection ("hit-and-run"), and with commensal bacteria potentially different from both due to additional physical mechanisms for avoiding immune detection. The Janus Immunogenicity Score (JIS) was recently developed to assess the likelihood of T cell recognition of an antigen, using an analysis that considers both binding of a peptide within the antigen by major histocompatability complex (MHC) and recognition of the peptide:MHC complex by cognate T cell receptor (TCR). This score was shown to be predictive of T effector vs. T regulatory or null responses in experimental data, as well as to distinguish viruses representative of the hit-and-stay vs. hit-and-run phenotypes. Here, JIS-based analyses were conducted in order to characterize the extent to which the pressure to avoid T cell recognition is manifested in genomic differences among representative hit-and-run, hit-and-stay, and commensal bacteria. Overall, extracellular proteins were found to have different JIS profiles from cytoplasmic ones. Contrasting the bacterial groups, extracellular proteins were shown to be quite different across the groups, much more so than intracellular proteins. The differences were evident even at the level of corresponding peptides in homologous protein pairs from hit-and-run and hit-and-stay bacteria. The multi-level analysis of patterns of immunogenicity across different groups of bacteria provides a new way to approach questions of bacterial immune camouflage or escape, as well as to approach the selection and optimization of candidates for vaccine design. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Is There an Association Between Heparin-Induced Thrombocytopenia (HIT) and Autoimmune Disease?

    Science.gov (United States)

    Klinkhammer, Brent; Gruchalla, Michael

    2018-03-01

    Heparin-induced thrombocytopenia (HIT) is a drug-induced, immunoglobulin G medicated autoimmune disorder associated with several negative clinical outcomes including increased morbidity, mortality, and increased medical costs. Previous studies have shown associations between comorbid autoimmune diseases, but there is little known about associations between HIT and autoimmunity. To provide clinical data to suggest an association between HIT and autoimmunity. Retrospective chart review of 59 cases with a diagnosis of HIT and 251 matched controls without a HIT diagnosis, comparing the prevalence of autoimmunity in each group. A single, large upper Midwest health care system. Patients with a diagnosis of HIT were significantly more likely to have a comorbid autoimmune disease than those without a HIT diagnosis (55.9% vs 10.8%, P HIT were significantly more likely to have a diagnosis of antiphospholipid syndrome (15.3% vs 0.0%, P HIT were significantly older than controls ( P HIT and autoimmune disease and suggests a need for more research into the relationship between HIT and autoimmunity. These results could alter the anticoagulation management of venous thromboembolism and acute coronary syndrome in patients with a previously identified autoimmune disease. Copyright© Wisconsin Medical Society.

  11. Do suburban residents want to pay for wide streets? a survey on consumer preference and ability to afford towards wide street and on-street parking in American suburbia.

    Science.gov (United States)

    2016-08-01

    All local governments in the U.S. set the street minimum width and cross-section design for local : neighborhood streets. Because local streets typically require no more than two traffic lanes (approx. 20 feet : wide), a minimum width of 26 feet or w...

  12. Do pigeons prefer alternatives that include near-hit outcomes?

    Science.gov (United States)

    Stagner, Jessica P; Case, Jacob P; Sticklen, Mary F; Duncan, Amanda K; Zentall, Thomas R

    2015-07-01

    Pigeons show suboptimal choice on a gambling-like task similar to that shown by humans. Humans also show a preference for gambles in which there are near hits (losses that come close to winning). In the present research, we asked if pigeons would show a preference for alternatives with near-hit-like trials. In Experiment 1, we included an alternative that presented a near hit, in which a stimulus associated with reinforcement (a presumed conditioned reinforcer) changed to a stimulus associated with the absence of reinforcement (a presumed conditioned inhibitor). The pigeons tended to avoid this alternative. In Experiment 2, we varied the duration of the presumed conditioned reinforcer (2 vs. 8 s) that changed to a presumed conditioned inhibitor (8 vs. 2 s) and found that the longer the conditioned reinforcer was presented, the more the pigeons avoided it. In Experiment 3, the near-hit alternative involved an ambiguous stimulus for 8 s that changed to a presumed conditioned reinforcer (or a presumed conditioned inhibitor) for 2 s, but the pigeons still avoided it. In Experiment 4, we controlled for the duration of the conditioned reinforcer by presenting it first for 2 s followed by the ambiguous stimulus for 8 s. Once again, the pigeons avoided the alternative with the near-hit trials. In all 4 experiments, the pigeons tended to avoid alternatives that provided near-hit-like trials. We concluded that humans may be attracted to near-hit trials because near-hit trials give them the illusion of control, whereas this does not appear to be a factor for pigeons. (c) 2015 APA, all rights reserved).

  13. Combined hit theory-microdosimetric explanation of cellular radiobiological action

    International Nuclear Information System (INIS)

    Bond, V.P.; Varma, M.N.

    1983-01-01

    Hit theory is combined with microdosimetry in a stochastic approach that explains the observed responses of cell populations exposed in radiation fields of different qualities. The central thesis is that to expose a population of cells in a low-level radiation field is to subject the cells to the potential for interaction with charged particles in the vicinity of the cells, quantifiable in terms of the charged particle fluence theta. When such an interaction occurs there is a resulting stochastic transfer of energy to a critical volume (CV) of cross section sigma, within the cell(s). The severity of cell injury is dependent on the amount of energy thus imparted, or the hit size. If the severity is above some minimal level, there is a non-zero probability that the injury will result in a quantal effect (e.g., a mutational or carcinogenic initial event, cell transformation). A microdosimetric proportional counter, viewed here as a phantom cell CV that permits measurements not possible in the living cell, is used to determine the incidence of hit cells and the spectrum of hit sizes. Each hit is then weighted on the basis of an empirically-determined function that provides the fraction of cells responding quantally, as a function of hit size. The sum of the hits so weighted provides the incidence of quantally-responding cells, for any amount of exposure theta in a radiation field of any quality or mixture qualities. The hit size weighting function for pink mutations in Tradescantia is discussed, as are its implications in terms of a replacement for RBE and dose equivalent. 14 references, 9 figures

  14. Lead generation and examples opinion regarding how to follow up hits.

    Science.gov (United States)

    Orita, Masaya; Ohno, Kazuki; Warizaya, Masaichi; Amano, Yasushi; Niimi, Tatsuya

    2011-01-01

    In fragment-based drug discovery (FBDD), not only identifying the starting fragment hit to be developed but also generating a drug lead from that starting fragment hit is important. Converting fragment hits to leads is generally similar to a high-throughput screening (HTS) hits-to-leads approach in that properties associated with activity for a target protein, such as selectivity against other targets and absorption, distribution, metabolism, excretion, and toxicity (ADME/Tox), and physicochemical properties should be taken into account. However, enhancing the potency of the fragment hit is a key requirement in FBDD, unlike HTS, because initial fragment hits are generally weak. This enhancement is presently achieved by adding additional chemical groups which bind to additional parts of the target protein or by joining or combining two or more hit fragments; however, strategies for effecting greater improvements in effective activity are needed. X-ray analysis is a key technology attractive for converting fragments to drug leads. This method makes it clear whether a fragment hit can act as an anchor and provides insight regarding introduction of functional groups to improve fragment activity. Data on follow-up chemical synthesis of fragment hits has allowed for the differentiation of four different strategies: fragment optimization, fragment linking, fragment self-assembly, and fragment evolution. Here, we discuss our opinion regarding how to follow up on fragment hits, with a focus on the importance of fragment hits as an anchor moiety to so-called hot spots in the target protein using crystallographic data. Copyright © 2011 Elsevier Inc. All rights reserved.

  15. Rare transformation to double hit lymphoma in Waldenstrom's macroglobulinemia.

    Science.gov (United States)

    Okolo, Onyemaechi N; Johnson, Ariel C; Yun, Seongseok; Arnold, Stacy J; Anwer, Faiz

    2017-08-01

    Waldenström macroglobulinemia (WM) is a lymphoproliferative lymphoma that is characterized by monoclonal immunoglobulin M (IgM) protein and bone marrow infiltration. Its incidence is rare and rarer still is its ability to transform to a B-cell lymphoma, particularly the aggressive diffuse large B-cell lymphoma, which bodes a poor prognosis. When transformation includes mutations of MYC, BCL-2 and/or BCL-6, it is known as a 'double hit' or 'triple hit' lymphoma respectively. This paper presents a rare case of WM with mutations positive for MYC and BCL2, making it a case of double hit B-cell lymphoplasmacytic lymphoma with plasmatic differentiation without morphological transformation to aggressive histology like DLBCL. The paper also broadens to include discussions on current topics in the classification, diagnosis, possible causes of transformation, and treatment of WM, including transformation to double hit lymphoma. The significance of this case lies in that the presence of double hit lymphoma-like genetic mutations in WM have not been previously described in the literature and potentially such changes are harbinger of extra-nodal presentation, aggressive growth, and possibly poor prognosis, if data from other double-hit lymphoma are extrapolated.

  16. Overview of the HIT-SI3 spheromak experiment

    Science.gov (United States)

    Hossack, A. C.; Jarboe, T. R.; Chandra, R. N.; Morgan, K. D.; Sutherland, D. A.; Everson, C. J.; Penna, J. M.; Nelson, B. A.

    2017-10-01

    The HIT-SI and HIT-SI3 spheromak experiments (a = 23 cm) study efficient, steady-state current drive for magnetic confinement plasmas using a novel method which is ideal for low aspect ratio, toroidal geometries. Sustained spheromaks show coherent, imposed plasma motion and low plasma-generated mode activity, indicating stability. Analysis of surface magnetic fields in HIT-SI indicates large n = 0 and 1 mode amplitudes and little energy in higher modes. Within measurement uncertainties all the n = 1 energy is imposed by the injectors, rather than being plasma-generated. The fluctuating field imposed by the injectors is sufficient to sustain the toroidal current through dynamo action whereas the plasma-generated field is not (Hossack et al., Phys. Plasmas, 2017). Ion Doppler spectroscopy shows coherent, imposed plasma motion inside r 10 cm in HIT-SI and a smaller volume of coherent motion in HIT-SI3. Coherent motion indicates the spheromak is stable and a lack of plasma-generated n = 1 energy indicates the maximum q is maintained below 1 for stability during sustainment. In HIT-SI3, the imposed mode structure is varied to test the plasma response (Hossack et al., Nucl. Fusion, 2017). Imposing n = 2, n = 3, or large, rotating n = 1 perturbations is correlated with transient plasma-generated activity. Work supported by the U.S. Department of Energy, Office of Science, Office of Fusion Energy Sciences, under Award Number DE-FG02-96ER54361.

  17. Street Lines, US, 2015, NAVTEQ

    Data.gov (United States)

    U.S. Environmental Protection Agency — NAVTEQ Streets for the United States. The Streets layer contains all roads plus all Road Network attributes such as direction of travel, lanes, dividers, speed...

  18. When VR really hits the streets

    Science.gov (United States)

    Morie, Jacquelyn F.

    2014-02-01

    Immersive Virtual Reality (VR) technology, while popular in the late part of the 20th Century, seemed to disappear from public view as social media took its place and captured the attention of millions. Now that a new generation of entrepreneurs and crowd-sourced funding campaigns have arrived, perhaps virtual reality is poised for a resurgence.

  19. Street as Sustainable City Structural Element

    Science.gov (United States)

    Leyzerova, A. V.; Bagina, E. J.

    2017-11-01

    Sustainability in architecture is nowadays of particular significance in the course of globalization and information density. The technospehere spontaneous development poses a threat to the sustainability of traditional urban forms where a street is one of the essential forming elements in the urban structure. The article proposes to consider formally compositional street features in relation to one of the traditional streets in the historic center of Ekaterinburg. The study examines the street-planning structure, the development of its skeleton elements, silhouette and fabric elevation characteristics as well as the scale characteristics and visual complexity of objects. The study provided architectural and artistic aspects of street sustainability, and limits of the appropriate scale and composition consistency under which the compatibility of alternative compositional forms existing at different times is possible.

  20. Street Prostitution Zones and Crime

    OpenAIRE

    Bisschop, Paul; Kastoryano, Stephen; van der Klaauw, Bas

    2015-01-01

    This paper studies the effects of introducing legal street prostitution zones on both registered and perceived crime. We exploit a unique setting in the Netherlands where legal street prostitution zones were opened in nine cities under different regulation systems. We provide evidence that the opening of these zones was not in response to changes in crime. Our difference-in-difference analysis using data on the largest 25 Dutch cities between 1994 and 2011 shows that opening a legal street pr...

  1. Fatal traffic injuries among children and adolescents in three cities (capital Budapest, Vilnius, and Tallinn).

    Science.gov (United States)

    Töro, Klára; Szilvia, Fehér; György, Dunay; Pauliukevicius, Alvydas; Caplinskiene, Marija; Raudys, Romas; Lepik, Delia; Tuusov, Jana; Vali, Marika

    2011-05-01

    Motor vehicle accidental injuries are a frequent cause of death among young children and adolescents. The goal of this study was to compare patterns of injury between three capitals (Budapest, Vilnius, and Tallinn). Information on 190 fatal traffic accidents (69 pedestrians, 14 bicyclists, and 107 motor vehicle occupants) between 2002 and 2006 was collected from databases of medico-legal autopsies. The role of victims in accidents, the location of injuries, cause of death, survival period, and blood alcohol levels were evaluated. One-hundred and forty-one (74%) victims had a passive role in traffic as pedestrians, passengers in cars, or public transport. In victims who died at the scene, the rate of head injury was higher than in cases who received medical treatment (odds ratio = 2.58, CI = 1.2-5.55, p = 0.0127). These results underline the importance of postmortem studies to examine the pathomechanism of fatal traffic accidental injuries and to provide information for the prevention of road traffic accidents against children and adolescents. © 2011 American Academy of Forensic Sciences.

  2. Creating a safe place for pediatric care: A no hit zone.

    Science.gov (United States)

    Frazier, Erin R; Liu, Gilbert C; Dauk, Kelly L

    2014-07-01

    Our goal was to create and implement a program, Kosair Children's Hospital's No Hit Zone, which trains health care workers in de-escalation techniques to address parental disruptive behaviors and physical discipline of children commonly encountered in the hospital environment. The Child Abuse Task Force, a multidisciplinary group, along with key hospital administrators developed specific content for the policy, as well as marketing and educational materials. The No Hit Zone policy designates Kosair Children's Hospital as "an environment in which no adult shall hit a child, no adult shall hit another adult, no child shall hit an adult, and no child shall hit another child. When hitting is observed, it is everyone's responsibility to interrupt the behavior as well as communicate system policy to those present." Via a multidisciplinary, collaborative approach, the No Hit Zone was successfully implemented at Kosair Children's Hospital in 2012. Cost was nominal, and the support of key hospital administrators was critical to the program's success. Education of health professionals on de-escalation techniques and intervention with families at the early signs of parental stress occurred via live sessions and online training via case-based scenarios. The No Hit Zone is an important program used to provide a safe and caring environment for all families and staff of Kosair Children's Hospital. Demand for the program continues, demonstrated by the establishment of No Hit Zones at other local hospitals and multiple outpatient clinics. This article offers information for other organizations planning to conduct similar initiatives. Copyright © 2014 by the American Academy of Pediatrics.

  3. HIT and brain reward function: A case of mistaken identity (theory).

    Science.gov (United States)

    Wright, Cory; Colombo, Matteo; Beard, Alexander

    2017-08-01

    This paper employs a case study from the history of neuroscience-brain reward function-to scrutinize the inductive argument for the so-called 'Heuristic Identity Theory' (HIT). The case fails to support HIT, illustrating why other case studies previously thought to provide empirical support for HIT also fold under scrutiny. After distinguishing two different ways of understanding the types of identity claims presupposed by HIT and considering other conceptual problems, we conclude that HIT is not an alternative to the traditional identity theory so much as a relabeling of previously discussed strategies for mechanistic discovery. Copyright © 2017. Published by Elsevier Ltd.

  4. A combined hit theory-microdosimetric explanation of cellular radiobiological action

    International Nuclear Information System (INIS)

    Bond, V.P.; Varma, M.N.

    1983-01-01

    Hit theory is combined with microdosimetry in a stochastic approach that explains the observed responses of cell populations exposed in radiation fields of different qualities. The central thesis is that to expose a population of cells in a low-level radiation field is to subject the cells to the potential for interaction with charged particles, quantifiable in terms of the charged particle fluence PHI. When such an interaction occurs there is resulting stochastic transfer of energy to a critical volume (CV) of cross-section σ within the cell(s). The severity of cell injury is dependent on the amount of energy thus imparted, or the hit size. If the severity is above some minimal level, there is a non-zero probability that the injury will result in a quantal effect (e.g., a mutational or carcinogenic initial event, cell transformation). A microdosimetric proportional counter, viewed here as a phantom cell CV that permits measurements not possible in the living cell, is used to determine the incidence of hit cells and the spectrum of hit sizes. Each hit is then weighted on the basis of an empirically determined function that provides the fraction of cells responding quantally, as a function of hit size. The sum of the hits so weighted provides the incidence of quantally responding cells, for any amount of exposure PHI in a radiation field of any quality or mixture of qualities. The hit size weighting function for pink mutations in Tradescantia is discussed, as are its implications in terms of a replacement for relative biological effectiveness and dose equivalent. (author)

  5. Cleaning up the Streets of Denver

    International Nuclear Information System (INIS)

    Stegen, R.L.; Wood, T.R.; Hackett, J.R.; Sogue, A.

    2006-01-01

    Between 1913 and 1924, several Denver area facilities extracted radium from carnotite ore mined from the Paradox basin region of Colorado. Tailings or abandoned ores from these facilities were apparently incorporated into asphalt used to pave approximately 7.2 kilometers (4.5 miles) of streets in Denver. A majority of the streets are located in residential areas. The radionuclides are bound within the asphalt matrix and pose minimal risk unless they are disturbed. The City and County of Denver (CCoD) is responsible for controlling repairs and maintenance on these impacted streets. Since 2002, the CCoD has embarked on a significant capital improvement project to remove the impacted asphalt for secure disposal followed by street reconstruction. To date, Parsons has removed approximately 55 percent of the impacted asphalt. This paper discusses the history of the Denver Radium Streets and summarizes on-going project efforts. (authors)

  6. PageRank, HITS and a unified framework for link analysis

    Energy Technology Data Exchange (ETDEWEB)

    Ding, Chris; He, Xiaofeng; Husbands, Parry; Zha, Hongyuan; Simon, Horst

    2001-10-01

    Two popular webpage ranking algorithms are HITS and PageRank. HITS emphasizes mutual reinforcement between authority and hub webpages, while PageRank emphasizes hyperlink weight normalization and web surfing based on random walk models. We systematically generalize/combine these concepts into a unified framework. The ranking framework contains a large algorithm space; HITS and PageRank are two extreme ends in this space. We study several normalized ranking algorithms which are intermediate between HITS and PageRank, and obtain closed-form solutions. We show that, to first order approximation, all ranking algorithms in this framework, including PageRank and HITS, lead to same ranking which is highly correlated with ranking by indegree. These results support the notion that in web resource ranking indegree and outdegree are of fundamental importance. Rankings of webgraphs of different sizes and queries are presented to illustrate our analysis.

  7. Street level society

    DEFF Research Database (Denmark)

    Vinum, Christine; Nissen, Morten

    2006-01-01

    This paper aims to reflect on research findings from different empirical studies of social work with young drug users and socially excluded young people in Copenhagen. In the paper we account for historical changes in social policy and interventions into young people's drug taking in Copenhagen......, and partly from the decentralizing and specializing efforts characteristic of the Danish welfare state and its institutions. We discuss a general turn towards street level interventions to address the problems of social exclusion, as well as different attempts to create what we term street level heterotopias...

  8. 76 FR 55914 - HIT Policy Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2011-09-09

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee's Workgroup Meetings; Notice of... be open to the public via dial-in access only. Name of Committees: HIT Policy Committee's Workgroups... standards, implementation specifications, and certification criteria are needed. Date and Time: The HIT...

  9. 76 FR 46297 - HIT Policy Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2011-08-02

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee's Workgroup Meetings; Notice of... be open to the public via dial-in access only. Name of Committees: HIT Policy Committee's Workgroups... standards, implementation specifications, and certification criteria are needed. Date and Time: The HIT...

  10. 76 FR 22399 - HIT Policy Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2011-04-21

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee's Workgroup Meetings; Notice of... be open to the public via dial-in access only. Name of Committees: HIT Policy Committee's Workgroups... standards, implementation specifications, and certification criteria are needed. Date and Time: The HIT...

  11. 76 FR 28784 - HIT Policy Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2011-05-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee's Workgroup Meetings; Notice of... be open to the public via dial-in access only. Name of Committees: HIT Policy Committee's Workgroups... standards, implementation specifications, and certification criteria are needed. Date and Time: The HIT...

  12. 75 FR 29762 - HIT Policy Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2010-05-27

    ... Technology HIT Policy Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National... only. Name of Committees: HIT Policy Committee's Workgroups: Meaningful Use, Privacy & Security Policy... specifications, and certification criteria are needed. Date and Time: The HIT Policy Committee Workgroups will...

  13. 76 FR 14974 - HIT Policy Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2011-03-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee's Workgroup Meetings; Notice of... be open to the public via dial-in access only. Name of Committees: HIT Policy Committee's Workgroups... standards, implementation specifications, and certification criteria are needed. Date and Time: The HIT...

  14. 76 FR 50735 - HIT Policy Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2011-08-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee's Workgroup Meetings; Notice of... be open to the public via dial-in access only. Name of Committees: HIT Policy Committee's Workgroups... standards, implementation specifications, and certification criteria are needed. Date and Time: The HIT...

  15. Air quality considerations for stormwater green street design.

    Science.gov (United States)

    Shaneyfelt, Kathryn M; Anderson, Andrew R; Kumar, Prashant; Hunt, William F

    2017-12-01

    Green streets are increasingly being used as a stormwater management strategy to mitigate stormwater runoff at its source while providing other environmental and societal benefits, including connecting pedestrians to the street. Simultaneously, human exposure to particulate matter from urban transportation is of major concern worldwide due to the proximity of pedestrians, drivers, and cyclists to the emission sources. Vegetation used for stormwater treatment can help designers limit the exposure of people to air pollutants. This goal can be achieved through the deliberate placement of green streets, along with strategic planting schemes that maximize pollutant dispersion. This communication presents general design considerations for green streets that combine stormwater management and air quality goals. There is currently limited guidance on designing green streets for air quality considerations; this is the first communication to offer suggestions and advice for the design of green stormwater streets in regards to their effects on air quality. Street characteristics including (1) the width to height ratio of the street to the buildings, (2) the type of trees and their location, and (3) any prevailing winds can have an impact on pollutant concentrations within the street and along sidewalks. Vegetation within stormwater control measures has the ability to reduce particulate matter concentrations; however, it must be carefully selected and placed within the green street to promote the dispersion of air flow. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Verbs in the lexicon: Why is hitting easier than breaking?

    Science.gov (United States)

    McKoon, Gail; Love, Jessica

    2011-11-01

    Adult speakers use verbs in syntactically appropriate ways. For example, they know implicitly that the boy hit at the fence is acceptable but the boy broke at the fence is not. We suggest that this knowledge is lexically encoded in semantic decompositions. The decomposition for break verbs (e.g. crack, smash) is hypothesized to be more complex than that for hit verbs (e.g. kick, kiss). Specifically, the decomposition of a break verb denotes that "an entity changes state as the result of some external force" whereas the decomposition for a hit verb denotes only that "an entity potentially comes in contact with another entity." In this article, verbs of the two types were compared in a lexical decision experiment - Experiment 1 - and they were compared in sentence comprehension experiments with transitive sentences (e.g. the car hit the bicycle and the car broke the bicycle) - Experiments 2 and 3. In Experiment 1, processing times were shorter for the hit than the break verbs and in Experiments 2 and 3, processing times were shorter for the hit sentences than the break sentences, results that are in accord with the complexities of the postulated semantic decompositions.

  17. Mixed Hitting-Time Models

    NARCIS (Netherlands)

    Abbring, J.H.

    2009-01-01

    We study mixed hitting-time models, which specify durations as the first time a Levy process (a continuous-time process with stationary and independent increments) crosses a heterogeneous threshold. Such models of substantial interest because they can be reduced from optimal-stopping models with

  18. Air quality considerations for stormwater green street design

    International Nuclear Information System (INIS)

    Shaneyfelt, Kathryn M.; Anderson, Andrew R.; Kumar, Prashant; Hunt, William F.

    2017-01-01

    Green streets are increasingly being used as a stormwater management strategy to mitigate stormwater runoff at its source while providing other environmental and societal benefits, including connecting pedestrians to the street. Simultaneously, human exposure to particulate matter from urban transportation is of major concern worldwide due to the proximity of pedestrians, drivers, and cyclists to the emission sources. Vegetation used for stormwater treatment can help designers limit the exposure of people to air pollutants. This goal can be achieved through the deliberate placement of green streets, along with strategic planting schemes that maximize pollutant dispersion. This communication presents general design considerations for green streets that combine stormwater management and air quality goals. There is currently limited guidance on designing green streets for air quality considerations; this is the first communication to offer suggestions and advice for the design of green stormwater streets in regards to their effects on air quality. Street characteristics including (1) the width to height ratio of the street to the buildings, (2) the type of trees and their location, and (3) any prevailing winds can have an impact on pollutant concentrations within the street and along sidewalks. Vegetation within stormwater control measures has the ability to reduce particulate matter concentrations; however, it must be carefully selected and placed within the green street to promote the dispersion of air flow. - Highlights: • Green streets can be used for both stormwater and air quality management. • Design considerations must be made to minimize human exposure to air pollutants. • Urban vegetation can improve air quality with careful selection and placement.

  19. Universal design characteristic on themed streets

    Science.gov (United States)

    Harsritanto, Bangun IR; Indriastjario; Wijayanti

    2017-12-01

    People around the world can access the streets to fulfil their daily activities regardless of their gender, age, and abilities. The streetscape is an urban public space which is built to facilitate the basic needs of people as social being. The themed street is an urban streetscape designed and built in detail with a theme or special purpose in an of urban development process. Universal design facilitates the full range of human diversity as physical appearance, perception, cognitive abilities, sizes, and shapes. By designing for the diversity, the specialized streets become more functional and user-friendly. The purpose of this study is to examine several design characteristics of themed streets in several countries from three different continents using universal design principles for giving proper directions to develop more user-friendly streets. Literature review and case study were used as research methods. The literature review was extracted and compiled from manuscripts, streetscape design books, and from universal design principles. Furthermore, the constructed theory were used to examine the case studies of themed streets. The findings indicated that themed streets’ character design were strongly influenced by local cultural aspect even though the basic guidelines were universal design principles; the resumed design direction can be suggested universal along with the richness of local aspects.

  20. 76 FR 46298 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-08-02

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: to provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held virtually on August 17, 2011...

  1. 76 FR 50734 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-08-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: to provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on September 28, 2011, from 9...

  2. 77 FR 2727 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-01-19

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: To provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on February 29, 2012, from 9...

  3. 76 FR 70455 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-11-14

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: to provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on December 14, 2011, from 9...

  4. 75 FR 5595 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2010-02-03

    ... Technology HIT Standards Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National... Health Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT... Federal Health IT Strategic Plan, and in accordance with policies developed by the HIT Policy Committee...

  5. 77 FR 73661 - HIT Standards Committee Advisory Meetings; Notice of Meetings

    Science.gov (United States)

    2012-12-11

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meetings; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: To provide... developed by the HIT Policy Committee. Date and Time: These meetings will be held on the following dates and...

  6. 76 FR 70454 - HIT Policy Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2011-11-14

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee's Workgroup Meetings; Notice of... be open to the public via dial-in access only. Name of Committees: HIT Policy Committee's Workgroups... certification criteria are needed. Date and Time: The HIT Policy Committee Workgroups will hold the following...

  7. 76 FR 28784 - HIT Standards Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2011-05-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee's Workgroup Meetings; Notice of... be open to the public via dial-in access only. Name of Committees: HIT Standards Committee's... implementation of the Federal Health IT Strategic Plan, and in accordance with policies developed by the HIT...

  8. 76 FR 50736 - HIT Standards Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2011-08-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee's Workgroup Meetings; Notice of... be open to the public via dial-in access only. Name of Committees: HIT Standards Committee's... implementation of the Federal Health IT Strategic Plan, and in accordance with policies developed by the HIT...

  9. 76 FR 14975 - HIT Standards Committee's Workgroup Meetings; Notice of Meetings

    Science.gov (United States)

    2011-03-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee's Workgroup Meetings; Notice of... be open to the public via dial-in access only. Name of Committees: HIT Standards Committee's... implementation of the Federal Health IT Strategic Plan, and in accordance with policies developed by the HIT...

  10. 77 FR 65691 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-10-30

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: To provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on November 13, 2012, from 9...

  11. 77 FR 50690 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-08-22

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: To provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on September 19, 2012, from 9...

  12. 75 FR 21628 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2010-04-26

    ... Technology HIT Standards Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Standards... Strategic Plan, and in accordance with policies developed by the HIT Policy Committee. Date and Time: The...

  13. 76 FR 55913 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-09-09

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: to provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held virtually on October 21, 2011...

  14. 77 FR 65690 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-10-30

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: To provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on December 19, 2012, from 9...

  15. The Regulation of Street Foods

    DEFF Research Database (Denmark)

    Forkour, John Boulard; Samuelsen, Helle; Yeboah, Eric Henry

    2017-01-01

    the challenges and negotiating strategies of regulators of street-vended foods in Ghana and analyses the implication for their relationship with street food vendors. The paper reveals that regulators operate in a context of limited resources, leading to a general feeling of neglect. In coping, regulators adopt...

  16. Street Papers, Work, and Begging

    DEFF Research Database (Denmark)

    Cockburn, Patrick Joseph

    2014-01-01

    Street papers are publications produced specifically for sale by the homeless and other vulnerable people in many countries around the world. Their social status is, however, often conspicuously unstable: ‘Get a job!’ has been reported as a common insult addressed to vendors, and street paper...

  17. Single-hit mechanism of tumour cell killing by radiation.

    Science.gov (United States)

    Chapman, J D

    2003-02-01

    To review the relative importance of the single-hit mechanism of radiation killing for tumour response to 1.8-2.0 Gy day(-1) fractions and to low dose-rate brachytherapy. Tumour cell killing by ionizing radiation is well described by the linear-quadratic equation that contains two independent components distinguished by dose kinetics. Analyses of tumour cell survival curves that contain six or more dose points usually provide good estimates of the alpha- and beta-inactivation coefficients. Superior estimates of tumour cell intrinsic radiosensitivity are obtained when synchronized populations are employed. The characteristics of single-hit inactivation of tumour cells are reviewed and compared with the characteristics of beta-inactivation. Potential molecular targets associated with single-hit inactivation are discussed along with strategies for potentiating cell killing by this mechanism. The single-hit mechanism of tumour cell killing shows no dependence on dose-rate and, consequently, no evidence of sublethal damage repair. It is uniquely potentiated by high linear-energy-transfer radiation, exhibits a smaller oxygen enhancement ratio and exhibits a larger indirect effect by hydroxyl radicals than the beta-mechanism. alpha-inactivation coefficients vary slightly throughout interphase but mitotic cells exhibit extremely high alpha-coefficients in the range of those observed for lymphocytes and some repair-deficient cells. Evidence is accumulating to suggest that chromatin in compacted form could be a radiation-hypersensitive target associated with single-hit radiation killing. Analyses of tumour cell survival curves demonstrate that it is the single-hit mechanism (alpha) that determines the majority of cell killing after doses of 2Gy and that this mechanism is highly variable between tumour cell lines. The characteristics of single-hit inactivation are qualitatively and quantitatively distinct from those of beta-inactivation. Compacted chromatin in tumour cells

  18. Assessing the lipophilicity of fragments and early hits

    Science.gov (United States)

    Mortenson, Paul N.; Murray, Christopher W.

    2011-07-01

    A key challenge in many drug discovery programs is to accurately assess the potential value of screening hits. This is particularly true in fragment-based drug design (FBDD), where the hits often bind relatively weakly, but are correspondingly small. Ligand efficiency (LE) considers both the potency and the size of the molecule, and enables us to estimate whether or not an initial hit is likely to be optimisable to a potent, druglike lead. While size is a key property that needs to be controlled in a small molecule drug, there are a number of additional properties that should also be considered. Lipophilicity is amongst the most important of these additional properties, and here we present a new efficiency index (LLEAT) that combines lipophilicity, size and potency. The index is intuitively defined, and has been designed to have the same target value and dynamic range as LE, making it easily interpretable by medicinal chemists. Monitoring both LE and LLEAT should help both in the selection of more promising fragment hits, and controlling molecular weight and lipophilicity during optimisation.

  19. Street Pastors : on security, care and faith

    NARCIS (Netherlands)

    van Steden, R.

    2018-01-01

    This paper presents a study of Street Pastors in Cardiff, the capital city of Wales. Street Pastors are Christian volunteers who look after vulnerable people in the night-time economy. In this manner, they provide ‘securitas’ through empathy and care. The motives of Street Pastors for engaging with

  20. 77 FR 16035 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-03-19

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: to provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on March 27, 2012, from 9 a.m...

  1. 76 FR 79684 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-12-22

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: to provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on January 25, 2012, from 9 a...

  2. 77 FR 15760 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-03-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: to provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on April 18, 2012, from 9 a.m...

  3. 76 FR 14976 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-03-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: To provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on April 20, 2011, from 9 a.m...

  4. 76 FR 39109 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-07-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: to provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on July 20, 2011, from 9 a.m...

  5. 76 FR 28782 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-05-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: To provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on June 22, 2011, from 9 a.m...

  6. 77 FR 27459 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-05-10

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: To provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on June 20, 2012, from 9 a.m...

  7. 77 FR 37408 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-06-21

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... be open to the public. Name of Committee: HIT Standards Committee. General Function of the Committee... with policies developed by the HIT Policy Committee. Date and Time: The meeting will be held on July 19...

  8. 77 FR 22787 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-04-17

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: to provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on May 24, 2012, from 9 a.m...

  9. 76 FR 22396 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-04-21

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: to provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on May 18, 2011, from 9 a.m...

  10. 77 FR 60438 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-10-03

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: To provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on October 17, 2012, from 9 a...

  11. 76 FR 9783 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-02-22

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: To provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on March 29, 2011, from 9 a.m...

  12. 77 FR 45353 - HIT Standards Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-07-31

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Standards Committee Advisory Meeting; Notice of... public. Name of Committee: HIT Standards Committee. General Function of the Committee: To provide... developed by the HIT Policy Committee. Date and Time: The meeting will be held on August 15, 2012, from 9:00...

  13. City Streets

    Data.gov (United States)

    Minnesota Department of Natural Resources — This data set contains roadway centerlines for city streets found on the USGS 1:24,000 mapping series. In some areas, these roadways are current through the 2000...

  14. Spatial Character Analysis of Streets as Public Spaces: The Case of Izmit Hurriyet and Cumhuriyet Street, Turkey

    Science.gov (United States)

    Özbayraktar, Mehtap; Pekdemir, Merve; Mırzaliyeva, Gumru

    2017-10-01

    The word “public” was first used to refer to the theatre audience in France in the mid-17th century. In the 18th century, it turned into the meaning of “public space incorporating a large variety of people and composed of acquaintances and strangers”. The concepts of publicity, public space, and public realm have been studied and described by many researchers in the course of time. These descriptions show the development of public space as well. In the very general sense, public spaces are areas of personal and social happiness; collective living spaces of the society; areas of expression of natural and cultural variety; and key elements providing a ground for the establishment of an identity. In the United Nations’ report on public spaces, public space is addressed under six groups: 1. The spaces we intensely used in our daily life; 2. Green open public spaces; 3. Public activity spaces which users can go in without any difficulty, are open to public, and are under protection; 4. Public sector realm (social agreements in which the people are represented, contribute to collective goods, and trust in the administrators elected); 5. City as a public space; 6. Cyberspace. As cities grow, public spaces transform and diversify. Attempts are made to meet the changing needs through types of space developed. However, the character of the existing public spaces, the distribution of open spaces and parks and their inadequacy, the destruction of public space, and the things that are required to be done stand as important issues to be addressed. One of the public spaces going through transformation are streets which we intensely use in our daily life. In general, streets are defined as roads with buildings on both sides in settlements such as provinces and districts whose boundaries are determined by neighbouring buildings. Some researchers have defined streets based on their social functions. According to them, streets are meeting spaces; spaces to deal with

  15. A C++ object-oriented toolkit for track finding with k-dimensional hits

    International Nuclear Information System (INIS)

    Uiterwijk, J.W.E.; Panman, J.; Vyver, B. van de

    2006-01-01

    A library is described for the recognition of tracks in a set of hits. The hits are assumed to be k-dimensional points (k-d), with k>=1, of which a subset can be grouped into tracks by using short-range correlations. A connection graph between the hits is created by sorting the hits first in k-d space using one of the developed, fast, k-space containers. The track-finding algorithm considers any connection between two hits as a possible track seed and grows these seeds into longer track segments using a modified depth-first search of the connection graph. All hit-acceptance decisions are called via abstract methods of an acceptance criterion class which isolates the library from the application's hit and track model. An application is tuned for a particular tracking environment by creating a concrete implementation for the hit and track acceptance calculations. The implementer is free to trade tracking time for acceptance complexity (influencing efficiency) depending on the requirements of the particular application. Results for simulated data show that the track finding is both efficient and fast even for high noise environments

  16. PLC based Smart Street Lighting Control

    OpenAIRE

    D.V.Pushpa Latha; K.R.Sudha; Swati Devabhaktuni

    2013-01-01

    Conventional street lighting systems in most of the areas are Online at regular intervals of time irrespective of the seasonal variations. The street lights are simply switched on at afternoon and turned off in the morning. The consequence is that a large amount of Power is wasted meaninglessly. As energy consumption is an issue of increasing interest, possible energy savings in public street lighting systems are recently discussed from different viewpoints. The purpose of this work is to des...

  17. Throat hit in users of the electronic cigarette: An exploratory study.

    Science.gov (United States)

    Etter, Jean-François

    2016-02-01

    A cross-sectional survey on the Internet in 2012-2014 was used to study the "throat hit," the specific sensation in the throat felt by users of e-cigarettes. Participants were 1672 current users of e-cigarettes, visitors of Websites dedicated to e-cigarettes and to smoking cessation. It was assessed whether the strength of the throat hit was associated with the characteristics of e-cigarettes and e-liquids, modifications of the devices, patterns of use, reasons for use, satisfaction with e-cigarettes, dependence on e-cigarettes, smoking behavior, and perceived effects on smoking. The strongest throat hit was obtained by using better-quality models and liquids with high nicotine content. Those who reported a "very strong" throat hit used liquids with 17.3 mg/mL nicotine, versus 7.1 mg/mL for those reporting a "very weak" hit (p e-cigarette models that provide high levels of nicotine, a strong throat hit, high satisfaction, and more effects on smoking, but may also be addictive, and models than contain less nicotine and are less addictive, but produce a weaker throat hit, are less satisfactory, and are possibly less efficient at helping people quit smoking. This trade-off must be kept in mind when regulating e-cigarettes. (c) 2016 APA, all rights reserved).

  18. Identifying and Synchronizing Health Information Technology (HIT) Events from FDA Medical Device Reports.

    Science.gov (United States)

    Kang, Hong; Wang, Frank; Zhou, Sicheng; Miao, Qi; Gong, Yang

    2017-01-01

    Health information technology (HIT) events, a subtype of patient safety events, pose a major threat and barrier toward a safer healthcare system. It is crucial to gain a better understanding of the nature of the errors and adverse events caused by current HIT systems. The scarcity of HIT event-exclusive databases and event reporting systems indicates the challenge of identifying the HIT events from existing resources. FDA Manufacturer and User Facility Device Experience (MAUDE) database is a potential resource for HIT events. However, the low proportion and the rapid evolvement of HIT-related events present challenges for distinguishing them from other equipment failures and hazards. We proposed a strategy to identify and synchronize HIT events from MAUDE by using a filter based on structured features and classifiers based on unstructured features. The strategy will help us develop and grow an HIT event-exclusive database, keeping pace with updates to MAUDE toward shared learning.

  19. High energy ion hit technique to local area using microbeam

    Energy Technology Data Exchange (ETDEWEB)

    Tanaka, Ryuichi; Kamiya, Tomihiro; Suda, Tamotsu; Sakai, Takuro; Hirao, Toshio; Kobayashi, Yasuhiko; Watanabe, Hiroshi [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment

    1997-03-01

    Single energetic ion hit technique has been developed as an application of ion microbeam technique, in order to study the effect of local damage or injury to materials and living organisms. The overall performance is basically defined by those of separate techniques: microbeam formation, microbeam positioning, single ion detection, detection signal processing, hit timing control, and hit verification. Recent progress on the developments of these techniques at JAERI-TIARA facility are reviewed. (author)

  20. [Addictive behavior of street children: interculturation and resilience].

    Science.gov (United States)

    Kommegne, T; Denoux, P; Bernoussi, A; Njiengwe, E F

    2014-09-01

    This research belongs to a more comprehensive study on the care of street children in Cameroon. The idea is to develop an analysis of the street pathology where symptoms such as addictive behavior and drug addiction can be found. Beside HIV AIDS, addictive behaviors are the main risk factors that many professionals have to face with while dealing with the street problems today. Through an intercultural approach, we examined the practices of addictive typology, their initiatory role and their function in the integration of the street system. We also analysed their importance in the survival strategies. After an overview of theoretical controversies that feed the debate on addictions, we questioned the impact of these practices on the street career through the prism of general theory of addictions, particularly the hedonic management model. Addiction helps to resist adversity, it helps to desist and then to begin a harmonious neo development despite the horrors of the street experience. We undertook a quantitative and qualitative study on a sample of 148 street children. We proposed to 128 of them a questionnaire focused on addictive behaviors and survival strategies in the street context. We notably evaluated the street career of 24 of them, using interviews and standardized tests to assess self-esteem (Coopersmith's SEI) frustration tolerance (Rosenweig's P-F) and self-efficacy (Sherer's SE Scale) in order to measure the impact of addictive behaviors on the resilience process. We found that the street career is essentially traumatic, and that addictive behaviors involving various integration strategies are strongly linked to the interculturation process through the identity strategies and the intercultural competences. Addiction itself is not significantly related to self-esteem issues but strongly impacts on self-efficacy and the ability to tolerate frustration. They allow the street children to withstand the street adversity but are a real obstacle to their

  1. The street school Srikandi as an empowerment model of humane education for the street girls of non halfway house in Surabaya

    Science.gov (United States)

    Setyowati, RRN; Yani, MT; Imron, A.

    2018-01-01

    The street children have not had a solid emotional mental, however they must deal into the life of street that harsh, competitive and tend to affect negatively for their personality development. Their where abouts on the street is not motivated by family economic factor only, but it is also influenced by the disharmony of role and function of family rules and social environment influences. The street children empowerment that had been conducted by the halfway house does not run effectively. This research was aimed to identify problems faced by the street girls, to describe the efforts to overcome the problems faced by the street girls, and also developing the empowerment model for the street girls in Surabaya who do not stay in the halfway house. This research used qualitative method. The problems are often experienced by the street girls, for instance violence. Besides, imitative behavior arises as a respond towards behavior that happened to them. The parents also play role in the process of social control. The empowerment model that is designed is the educational empowerment through revitalization of family rules. Moreover, life skills education has to be strengthened to improve the welfare standard of living.

  2. Database for High Throughput Screening Hits (dHITS): a simple tool to retrieve gene specific phenotypes from systematic screens done in yeast.

    Science.gov (United States)

    Chuartzman, Silvia G; Schuldiner, Maya

    2018-03-25

    In the last decade several collections of Saccharomyces cerevisiae yeast strains have been created. In these collections every gene is modified in a similar manner such as by a deletion or the addition of a protein tag. Such libraries have enabled a diversity of systematic screens, giving rise to large amounts of information regarding gene functions. However, often papers describing such screens focus on a single gene or a small set of genes and all other loci affecting the phenotype of choice ('hits') are only mentioned in tables that are provided as supplementary material and are often hard to retrieve or search. To help unify and make such data accessible, we have created a Database of High Throughput Screening Hits (dHITS). The dHITS database enables information to be obtained about screens in which genes of interest were found as well as the other genes that came up in that screen - all in a readily accessible and downloadable format. The ability to query large lists of genes at the same time provides a platform to easily analyse hits obtained from transcriptional analyses or other screens. We hope that this platform will serve as a tool to facilitate investigation of protein functions to the yeast community. © 2018 The Authors Yeast Published by John Wiley & Sons Ltd.

  3. All hypertopologies are hit-and-miss

    Directory of Open Access Journals (Sweden)

    Somshekhar Naimpally

    2002-04-01

    Full Text Available We solve a long standing problem by showing that all known hypertopologies are hit-and-miss. Our solution is not merely of theoretical importance. This representation is useful in the study of comparison of the Hausdorff-Bourbaki or H-B uniform topologies and the Wijsman topologies among themselves and with others. Up to now some of these comparisons needed intricate manipulations. The H-B uniform topologies were the subject of intense activity in the 1960's in connection with the Isbell-Smith problem. We show that they are proximally locally finite topologies from which the solution to the above problem follows easily. It is known that the Wijsman topology on the hyperspace is the proximal ball (hit-and-miss topology in”nice” metric spaces including the normed linear spaces. With the introduction of a new far-miss topology we show that the Wijsman topology is hit-and-miss for all metric spaces. From this follows a natural generalization of the Wijsman topology to the hyperspace of any T1 space. Several existing results in the literature are easy consequences of our work.

  4. The Education Rights of Street-Involved Children

    Directory of Open Access Journals (Sweden)

    Sonja Grover

    2010-05-01

    Full Text Available This paper provides an overview of certain key aspects of the practical and legal situation of street-involved children globally. The inadequate protection of these children under both domestic and international law is addressed. The diversity of the population of street-involved children is considered as is the fact that this group is composed of both legally stateless and de facto stateless children. The relationship of street involvement to child labor, various health risks and victimization is discussed. The educational needs of older street-involved children are addressed including their right to participate in decision-making regarding aspects of educational service design and delivery. The overall objective of this paper is to encourage those who are involved in, or could impact upon educational policy to include street-involved children in their educational planning implementation and advocacy efforts.

  5. Cosmic Ray Hit Detection with Homogenous Structures

    Science.gov (United States)

    Smirnov, O. M.

    Cosmic ray (CR) hits can affect a significant number of pixels both on long-exposure ground-based CCD observations and on the Space Telescope frames. Thus, methods of identifying the damaged pixels are an important part of the data preprocessing for practically any application. The paper presents an implementation of a CR hit detection algorithm based on a homogenous structure (also called cellular automata ), a concept originating in artificial intelligence and dicrete mathematics. Each pixel of the image is represented by a small automaton, which interacts with its neighbors and assumes a distinct state if it ``decides'' that a CR hit is present. On test data, the algorithm has shown a high detection rate (~0.7 ) and a low false alarm rate (frame. A homogenous structure is extremely trainable, which can be very important for processing large batches of data obtained under similar conditions. Training and optimizing issues are discussed, as well as possible other applications of this concept to image processing.

  6. Modelling traffic pollution in streets

    Energy Technology Data Exchange (ETDEWEB)

    Berkowicz, R.; Hertel, O. [National Environmental Research Inst., Dept. of Atmospheric Environment, Roskilde (Denmark); Larsen, S.E.; Soerensen, N.N.; Nielsen, M. [Risoe National Lab., Dept. of Meteorology and Wind Energy, Roskilde (Denmark)

    1997-01-01

    This report concerns mainly the subject related to modelling air pollution from traffic in urban streets. A short overview is presented over the theoretical aspects and examples of most commonly used methods and models are given. Flow and dispersion conditions in street canyons are discussed and the presentation is substantiated with the analysis of the experimental data. The main emphasis is on the modelling methods that are suitable for routine applications and a more detailed presentation is given of the Operational Street Pollution Model (OSPM), which was developed by the National Environmental Research Institute. The model is used for surveillance of air pollution from traffic in Danish cities and also for special air pollution studies. (au) 76 refs.

  7. Smart street lighting : The advantages of LED street lighting and a smart control system in Uppsala municipality

    OpenAIRE

    Sjöberg, Inga; Gidén Hember, Amanda; Wallerström, Carolina

    2017-01-01

    The purpose of this bachelor thesis is to examine how LED street lights and a smart street light control system can reduce the energy consumption, costs and in extension the CO2 equivalents in a geographically delimited area. In 2015 the municipality of Sala installed LED armatures connected to a smart control system in the whole municipality. The smart control system enables for instance adjustment of the light intensity at specific times during the day and a supervision of the street light ...

  8. A fast DSP-based calorimeter hit scanning system

    International Nuclear Information System (INIS)

    Sekikawa, S.; Arai, I.; Suzuki, A.; Watanabe, A.; Marlow, D.R.; Mindas, C.R.; Wixted, R.L.

    1997-01-01

    A custom made digital signal processor (DSP) based system has been developed to scan calorimeter hits read by a 32-channel FASTBUS waveform recorder board. The scanner system identifies hit calorimeter elements by surveying their discriminated outputs. This information is used to generate a list of addresses, which guides the read-out process. The system is described and measurements of the scan times are given. (orig.)

  9. Generative Street Addresses from Satellite Imagery

    Directory of Open Access Journals (Sweden)

    İlke Demir

    2018-03-01

    Full Text Available We describe our automatic generative algorithm to create street addresses from satellite images by learning and labeling roads, regions, and address cells. Currently, 75% of the world’s roads lack adequate street addressing systems. Recent geocoding initiatives tend to convert pure latitude and longitude information into a memorable form for unknown areas. However, settlements are identified by streets, and such addressing schemes are not coherent with the road topology. Instead, we propose a generative address design that maps the globe in accordance with streets. Our algorithm starts with extracting roads from satellite imagery by utilizing deep learning. Then, it uniquely labels the regions, roads, and structures using some graph- and proximity-based algorithms. We also extend our addressing scheme to (i cover inaccessible areas following similar design principles; (ii be inclusive and flexible for changes on the ground; and (iii lead as a pioneer for a unified street-based global geodatabase. We present our results on an example of a developed city and multiple undeveloped cities. We also compare productivity on the basis of current ad hoc and new complete addresses. We conclude by contrasting our generative addresses to current industrial and open solutions.

  10. Public Reactions to New Street Tree Planting

    Directory of Open Access Journals (Sweden)

    Ruth A. Rae

    2010-01-01

    Full Text Available MillionTreesNYC, which has the goal of planting one million trees in New York City by 2017, is intended to make New York City a greener, more sustainable city and is part of the Mayor’s comprehensive long term strategic plan, PlaNYC. Through planting a tree at every suitable sidewalk location in the city, the City of New York is transforming blocks and communities, and providing a variety of environmental, social and aesthetic benefits. This article examines the large scale municipal planting of new street trees and the reaction by some of the pubic to this planting.Trees offer benefits to the city overall, but the public may not understand these benefits or the street tree planting process. Between 2007 and 2009, the Department of Parks & Recreation planted 53,235 new street trees, and received 4,108 items of correspondence from the public. The majority of this correspondence consisted of public comments about the City’s new street tree planting policies and processes including placement objections, maintenance concerns, reports of resultant damage from tree planting operations, requests for new street trees and reports of tree conditions.This study describes the operational policies that guide New York City's municipal street tree planting, and results of content and spatial analysis of the correspondence. Qualitative analysis of the correspondence revealed the public perceptions and concerns related to the MillionTreesNYC program. Spatial analysis explored the relationship between the planting locations of new street trees and the locations of the citizen correspondence.Public reactions to this large scale municipal planting are related to the dual public and private nature of the sidewalk, issues of territoriality, responsibility, aesthetics and place attachment. Correspondence volume was associated with the scale of the new street tree block planting program, and the effectiveness of NYC’s 311 Customer Service Center. The discussion

  11. Passive control potentials of trees and on-street parked cars in reduction of air pollution exposure in urban street canyons

    International Nuclear Information System (INIS)

    Abhijith, K.V.; Gokhale, Sharad

    2015-01-01

    This study investigates the passive-control-potentials of trees and on-street parked cars on pedestrian exposure to air pollutants in a street canyon using three-dimensional CFD. Since, according to some studies trees deteriorate air quality and cars parked roadside improve it, the combine as well as separate effects of trees and on-street parked cars have been examined. For this, different tree canopy layouts and parking configurations have been developed and pedestrian exposure for each has been analysed. The results showed, for example, tree crown with high porosity and low-stand density in combination with parallel or perpendicular car parking reduced the pedestrian exposure considerably. - Highlights: • Trees and on-street parked cars can manipulate pollutant levels in street canyons. • Low stand density trees with 0° or 90° car parking reduce pedestrian exposure. • Trees with medium crown, high porosity, low stand density reduce pollutant levels. - This study investigated the combination of trees and on-street parked cars to manipulate pollutant levels in urban street canyons to reduce pedestrian exposure

  12. [Street social education: historical, political and pedagogical bases].

    Science.gov (United States)

    de Oliveira, Walter Ferreira

    2007-01-01

    This work is about street social education as a pedagogical system that started in Latin America in the late 1970s, as the street population formed mostly by children and adolescents called for attention. The first street social educators were 'pastoral' agents working at the praça da Sé a place with large numbers of street children in São Paulo. Based on the Liberation Theology and on the pedagogies developed by Paulo Freire, Celestine Freinet, Anton Makarenko, and Emília Ferreiro, the street educators developed a conceptual field and participated in the promulgation of the 1988 Federal Constitution, particularly by writing and introducing the 'Estatuto da Criança e do Adolescente' (the 'Child and Adolescent Statute'). Street social education is currently latent and suffering the consequences of program discontinuity caused by successive changes of government. It is, therefore important to know the conceptual proposals.

  13. Alcohol in urban streetscapes: a comparison of the use of Google Street View and on-street observation.

    Science.gov (United States)

    Clews, Chris; Brajkovich-Payne, Roza; Dwight, Emily; Ahmad Fauzul, Ayob; Burton, Madeleine; Carleton, Olivia; Cook, Julie; Deroles, Charlotte; Faulkner, Ruby; Furniss, Mary; Herewini, Anahera; Huband, Daymen; Jones, Nerissa; Kim, Cho Wool; Li, Alice; Lu, Jacky; Stanley, James; Wilson, Nick; Thomson, George

    2016-05-26

    Alcohol-related harm is a major global health issue, and controls on alcohol marketing are one intervention utilized by governments. This study investigated the use of Google Street View (GSV) as a novel research method for collecting alcohol-related data in the urban environment. The efficacy of GSV and on-street observation by observer teams was compared by surveying 400 m stretches of 12 streets in Wellington, the capital city of New Zealand. Data on alcohol sale, alcohol-related advertising, health promotion materials, regulatory information and visible alcohol consumption were collected. A total of 403 retailers with evidence of alcohol sales and 1161 items of alcohol-related communication were identified in on-street observation. Of the latter, 1028 items (89 %) were for alcohol marketing and 133 (11 %) were for alcohol-related health promotion and alcohol regulation. GSV was found to be a less sensitive tool than on-street observation with only 50 % of the alcohol venues identified and 52 % of the venue-associated brand marketing identified. A high degree of inter-observer reliability was generally found between pairs of observers e.g., for the detection of alcohol retail venues the intra-class correlation coefficient (ICC) was 0.93 (95 % CI: 0.78 to 0.98) for on-street observation and 0.85 (95 % CI: 0.49 to 0.96) for using GSV. GSV does not seem suitable for the comprehensive study of the influences on alcohol consumption in the urban streetscape. However, it may still have value for large, static objects in the environment and be more time efficient than traditional on-street observation measures, especially when used to collect data across a wide geographical area. Furthermore, GSV might become a more useful research tool in settings with better image quality (such as more 'footpath views') and with more regularly updated GSV imagery.

  14. Overlapping Open Clusters NGC 1750 and NGC 1758 behind the Taurus Dark Clouds. II. CCD Photometry in the Vilnius System

    Directory of Open Access Journals (Sweden)

    Straižys V.

    2003-09-01

    Full Text Available Seven-color photometry in the Vilnius system has been obtained for 420 stars down to V = 16 mag in the area containing the overlapping open clusters NGC 1750 and NGC 1758 in Taurus. Spectral and luminosity classes, color excesses, interstellar extinctions and distances are given for 287 stars. The classification of stars is based on their reddening-free Q-parameters. 18 stars observed photoelectrically were used as standards. The extinction vs. distance diagram exhibits the presence of one dust cloud at a distance of 175 pc which almost coincides with a distance of other dust clouds in the Taurus complex. The clusters NGC 1750 and NGC 1758 are found to be at the same distance of ~760 pc and may penetrate each other. Their interstellar extinction AV is 1.06 mag which corresponds to EB-V = 0.34 mag.

  15. Detecting Themed Streets Using a Location Based Service Application

    Directory of Open Access Journals (Sweden)

    Byeongsuk Ji

    2016-07-01

    Full Text Available Various themed streets have recently been developed by local governments in order to stimulate local economies and to establish the identity of the corresponding places. However, the motivations behind the development of some of these themed street projects has been based on profit, without full considerations of people’s perceptions of their local areas, resulting in marginal effects on the local economies concerned. In response to this issue, this study proposed a themed street clustering method to detect the themed streets of a specific region, focusing on the commercial themed street, which is more prevalent than other types of themed streets using location based service data. This study especially uses “the street segment” as a basic unit for analysis. The Sillim and Gangnam areas of Seoul, South Korea were chosen for the evaluation of the adequacy of the proposed method. By comparing trade areas that were sourced from a market analysis report by a reliable agent with the themed streets detected in this study, the experiment results showed high proficiency of the proposed method.

  16. Modelling Pollutant Dispersion in a Street Network

    Science.gov (United States)

    Salem, N. Ben; Garbero, V.; Salizzoni, P.; Lamaison, G.; Soulhac, L.

    2015-04-01

    This study constitutes a further step in the analysis of the performances of a street network model to simulate atmospheric pollutant dispersion in urban areas. The model, named SIRANE, is based on the decomposition of the urban atmosphere into two sub-domains: the urban boundary layer, whose dynamics is assumed to be well established, and the urban canopy, represented as a series of interconnected boxes. Parametric laws govern the mass exchanges between the boxes under the assumption that the pollutant dispersion within the canopy can be fully simulated by modelling three main bulk transfer phenomena: channelling along street axes, transfers at street intersections, and vertical exchange between street canyons and the overlying atmosphere. Here, we aim to evaluate the reliability of the parametrizations adopted to simulate these phenomena, by focusing on their possible dependence on the external wind direction. To this end, we test the model against concentration measurements within an idealized urban district whose geometrical layout closely matches the street network represented in SIRANE. The analysis is performed for an urban array with a fixed geometry and a varying wind incidence angle. The results show that the model provides generally good results with the reference parametrizations adopted in SIRANE and that its performances are quite robust for a wide range of the model parameters. This proves the reliability of the street network approach in simulating pollutant dispersion in densely built city districts. The results also show that the model performances may be improved by considering a dependence of the wind fluctuations at street intersections and of the vertical exchange velocity on the direction of the incident wind. This opens the way for further investigations to clarify the dependence of these parameters on wind direction and street aspect ratios.

  17. Psychosocial profile of institutionalised street children in Alexandria ...

    African Journals Online (AJOL)

    Objective: The phenomenon of street children in Egypt constitutes a public health concern. This study aimed to investigate the characteristics of institutionalised street children in Alexandria, to compare the prevalence of substance abuse and conduct disorder between street children and school children, and to identify ...

  18. Street Food Consumption and its associated socio-demographic ...

    African Journals Online (AJOL)

    Street Food Consumption and its associated socio-demographic factors in Oyo town, Nigeria. ... Abstract. Background: Contemporary life-styles have made street foods to be an important meal option in Nigeria. They contribute ... Nutrition education is suggested for people to make a better choice of nourishing street foods.

  19. Social and economic analysis of the demand for public transport in Vilnius

    Directory of Open Access Journals (Sweden)

    D. Griškevičienė

    2003-08-01

    Full Text Available To determine the demand for public transport on the market, a survey was conducted in 2001 - 2002 concerning the situation in the suburban zones of newly - built up districts where public transport is either inaccessible or poorly developed. The analysis was based on major social and economic factors determining the demand for transport. They are: demographic structure and development, restructuring of productive forces and space planning; employment and unemployment; income and poverty; social insurance, pensions and welfare; the household structure; income and expenditures; mobility of the inhabitants and motorization. The accessibility of transport services to passengers and the choice of transport facilities is closely related to their purchasing power. The offer of public transport services is lower than the demand, especially in the suburbs. As a result, the competition of automobiles is very strong there: the preference given to a car is determined by inaccessibility of public transport on the route for 22 % of the inhabitants, while for 20 % the reason was long way to a bus stop or large intervals in the schedule of public transport facilities. Based on the results obtained, the public transport system in Vilnius should be developed along three main lines: 1 raising the quality of public transport provided on fixed routes; 2 revising and updating the system of fares; 3 integrating the suburban public transport system into the central city transport system. These are the priority tasks associated with general goals of improving the system of public transport so that it could satisfy the needs of the passengers in the city.

  20. On the escape of pollutants from urban street canyons

    Energy Technology Data Exchange (ETDEWEB)

    Baik, J.J.; Kim, J.J. [Kwangju Inst. of Science and Technology (Korea). Dept. of Environmental Science and Engineering

    2002-07-01

    Pollutant transport from urban street canyons is numerically investigated using a two-dimensional flow and dispersion model. The ambient wind blows perpendicular to the street and passive pollutants are released at the street level. Results from the control experiment with a street aspect ratio of 1 show that at the roof level of the street canyon, the vertical turbulent flux of pollutants is upward everywhere and the vertical flux of pollutants by mean flow is upward or downward. The horizontally integrated vertical flux of pollutants by mean flow at the roof level of the street canyon is downward and its magnitude is much smaller than that by turbulent process. These results indicate that pollutants escape from the street canyon mainly by turbulent process and that the net effect of mean flow is to make some escaped pollutants reenter the street canyon. Further experiments with different inflow turbulence intensities, inflow wind speeds, and street aspect ratio confirm the findings from the control experiment. In the case of two isolated buildings, the horizontally integrated vertical flux of pollutants by mean flow is upward due to flow separation but the other main results are the same as those from the control experiment. (author)

  1. Social and economic characteristics of street youth by gender and level of street involvement in Eldoret, Kenya.

    Directory of Open Access Journals (Sweden)

    Rebecca Sorber

    Full Text Available Street-connected youth are a neglected and vulnerable population, particularly in resource-constrained settings. The development of interventions and supports for this population requires insight into how they live. This study describes the social and economic characteristics of a convenience sample of street youth (SY in Eldoret, Kenya.Participants were eligible if they were aged 12-21, living in Eldoret, spending days only (part-time, or nights and days on the street (full-time and able and willing to consent or assent. Data were collected using a standardized interview conducted in English or Kiswahili. Binary dependent variables were having been arrested and/or jailed, and first priority for spending money (food vs. other. Nominal categorical dependent variables included major source of support, and major reason for being street-involved. Multivariable analysis used logistic regression models to examine the association of gender and level of street-involvement with social and economic factors of interest adjusting for age and length of time on the street. Data were analyzed using SAS 9.3.Of the 200 SY enrolled, 41% were female, mean age of 16.3 years; 71% were on the street full-time, and 29% part-time. Compared with part-time SY, full-time SY were more likely to have been arrested (Adjusted Odds Ratio [AOR]: 2.33, 95% Confidence Interval [95%CI]:1.01-5.35, name food as their first spending priority (AOR: 2.57, 95%CI:1.03-6.45, have left home due to violence (AOR: 5.54, 95%CI: 1.67-18.34, and more likely to report friends on the street as a major source of support (AOR: 3.59, 95% CI: 1.01-12.82. Compared with females, males were more likely to have ever been arrested (AOR: 2.66, 95%CI:1.14-6.18, and to have ever been jailed (AOR: 3.22, 95%CI:1.47-7.02.These results suggest a high degree of heterogeneity and vulnerability among SY in this setting. There is an urgent need for interventions taking into consideration these characteristics.

  2. OpenStreetMap over WMS

    Directory of Open Access Journals (Sweden)

    Přemysl Vohnout

    2010-02-01

    Full Text Available This paper discuss the issues which we faced, while preparing WMS server with OpenStreetMap data of whole Europe. This article is divided into three sections. First is about mandatory applications which are required for working WMS service with OpenStreetMap data. Second is focused on tuning up PostgreSQL. Third is focused on rendering time improvement of layers.

  3. POLE-LIKE STREET FURNITURE DECOMPOSTION IN MOBILE LASER SCANNING DATA

    Directory of Open Access Journals (Sweden)

    F. Li

    2016-06-01

    Full Text Available Automatic semantic interpretation of street furniture has become a popular topic in recent years. Current studies detect street furniture as connected components of points above the street level. Street furniture classification based on properties of such components suffers from large intra class variability of shapes and cannot deal with mixed classes like traffic signs attached to light poles. In this paper, we focus on the decomposition of point clouds of pole-like street furniture. A novel street furniture decomposition method is proposed, which consists of three steps: (i acquirement of prior-knowledge, (ii pole extraction, (iii components separation. For the pole extraction, a novel global pole extraction approach is proposed to handle 3 different cases of street furniture. In the evaluation of results, which involves the decomposition of 27 different instances of street furniture, we demonstrate that our method decomposes mixed classes street furniture into poles and different components with respect to different functionalities.

  4. Pole-Like Street Furniture Decompostion in Mobile Laser Scanning Data

    Science.gov (United States)

    Li, F.; Oude Elberink, S.; Vosselman, G.

    2016-06-01

    Automatic semantic interpretation of street furniture has become a popular topic in recent years. Current studies detect street furniture as connected components of points above the street level. Street furniture classification based on properties of such components suffers from large intra class variability of shapes and cannot deal with mixed classes like traffic signs attached to light poles. In this paper, we focus on the decomposition of point clouds of pole-like street furniture. A novel street furniture decomposition method is proposed, which consists of three steps: (i) acquirement of prior-knowledge, (ii) pole extraction, (iii) components separation. For the pole extraction, a novel global pole extraction approach is proposed to handle 3 different cases of street furniture. In the evaluation of results, which involves the decomposition of 27 different instances of street furniture, we demonstrate that our method decomposes mixed classes street furniture into poles and different components with respect to different functionalities.

  5. A review of variables of urban street connectivity for spatial connection

    International Nuclear Information System (INIS)

    Mohamad, W S N W; Said, I

    2014-01-01

    Several studies on street connectivity in cities and towns have been modeled on topology, morphology, technology and psychology of people living in the urban environment. Street connectivity means the connection of streets that offers people alternative routes. However, there emerge difficulties to determine the suitable variables and analysis to be chosen in defining the accurate result for studies street connectivity. The aim of this paper is to identify variables of street connectivity by applying GIS and Space Syntax. This paper reviews the variables of street connectivity from 15 past articles done in 1990s to early 2000s from journals of nine disciplines on Environment and Behavior, Planning and Design, Computers, Environment and Urban Systems, Applied Earth Observation and Geo-information, Environment and Planning, Physica A: Statistical Mechanics and its Applications, Environmental Psychology, Social Science and Medicine and Building and Environment. From the review, there are four variables found for street connectivity: link (streets-streets, street-nodes or node-streets, nodes-nodes), accessibility, least-angle, and centrality. Space syntax and GIS are suitable tools to analyze the four variables relating to systematic street systems for pedestrians. This review implies that planners of the street systems, in the aspect of street connectivity in cities and towns, should consider these four variables

  6. A review of variables of urban street connectivity for spatial connection

    Science.gov (United States)

    Mohamad, W. S. N. W.; Said, I.

    2014-02-01

    Several studies on street connectivity in cities and towns have been modeled on topology, morphology, technology and psychology of people living in the urban environment. Street connectivity means the connection of streets that offers people alternative routes. However, there emerge difficulties to determine the suitable variables and analysis to be chosen in defining the accurate result for studies street connectivity. The aim of this paper is to identify variables of street connectivity by applying GIS and Space Syntax. This paper reviews the variables of street connectivity from 15 past articles done in 1990s to early 2000s from journals of nine disciplines on Environment and Behavior, Planning and Design, Computers, Environment and Urban Systems, Applied Earth Observation and Geo-information, Environment and Planning, Physica A: Statistical Mechanics and its Applications, Environmental Psychology, Social Science and Medicine and Building and Environment. From the review, there are four variables found for street connectivity: link (streets-streets, street-nodes or node-streets, nodes-nodes), accessibility, least-angle, and centrality. Space syntax and GIS are suitable tools to analyze the four variables relating to systematic street systems for pedestrians. This review implies that planners of the street systems, in the aspect of street connectivity in cities and towns, should consider these four variables.

  7. Sensation Seeking in Street Violence

    DEFF Research Database (Denmark)

    Heinskou, Marie Bruvik; Liebst, Lasse Suonperä

    Sensation seeking leads to violence—runs an influential hypothesis in the social scientific study of violent behavior. Although studies confirm that violence is sometimes structured by sensation-seeking motives, the literature seldom comments on the limits to this explanation of violence....... The present study examines the scale of violence motivated by sensation seeking and the degree to which there are several distinct forms of sensation seeking motives operative in violence, rather than a sensation-seeking motive in the singular. The study draws on a sample of situations from Copenhagen...... involving street violence, which are coded quantitatively and qualitatively. Our analysis shows that sensation seeking only seldom seems to play a role in the structuring of street violence. Moreover, the data indicate that sensation seeking finds expression in street violence situations in two different...

  8. Characteristics of flow and reactive pollutant dispersion in urban street canyons

    Science.gov (United States)

    Park, Soo-Jin; Kim, Jae-Jin; Kim, Minjoong J.; Park, Rokjin J.; Cheong, Hyeong-Bin

    2015-05-01

    In this study, the effects of aspect ratio defined as the ratio of building height to street width on the dispersion of reactive pollutants in street canyons were investigated using a coupled CFD-chemistry model. Flow characteristics for different aspect ratios were analyzed first. For each aspect ratio, six emission scenarios with different VOC-NOX ratios were considered. One vortex was generated when the aspect ratio was less than 1.6 (shallow street canyon). When the aspect ratio was greater than 1.6 (deep street canyon), two vortices were formed in the street canyons. Comparing to previous studies on two-dimensional street canyons, the vortex center is slanted toward the upwind building and reverse and downward flows are dominant in street canyons. Near the street bottom, there is a marked difference in flow pattern between in shallow and deep street canyons. Near the street bottom, reverse and downward flows are dominant in shallow street canyon and flow convergence exists near the center of the deep street canyons, which induces a large difference in the NOX and O3 dispersion patterns in the street canyons. NOX concentrations are high near the street bottom and decreases with height. The O3 concentrations are low at high NO concentrations near the street bottom because of NO titration. At a low VOC-NOX ratio, the NO concentrations are sufficiently high to destroy large amount of O3 by titration, resulting in an O3 concentration in the street canyon much lower than the background concentration. At high VOC-NOX ratios, a small amount of O3 is destroyed by NO titration in the lower layer of the street canyons. However, in the upper layer, O3 is formed through the photolysis of NO2 by VOC degradation reactions. As the aspect ratio increases, NOX (O3) concentrations averaged over the street canyons decrease (increase) in the shallow street canyons. This is because outward flow becomes strong and NOX flux toward the outsides of the street canyons increases

  9. "Hit-and-Run" leaves its mark: catalyst transcription factors and chromatin modification.

    Science.gov (United States)

    Varala, Kranthi; Li, Ying; Marshall-Colón, Amy; Para, Alessia; Coruzzi, Gloria M

    2015-08-01

    Understanding how transcription factor (TF) binding is related to gene regulation is a moving target. We recently uncovered genome-wide evidence for a "Hit-and-Run" model of transcription. In this model, a master TF "hits" a target promoter to initiate a rapid response to a signal. As the "hit" is transient, the model invokes recruitment of partner TFs to sustain transcription over time. Following the "run", the master TF "hits" other targets to propagate the response genome-wide. As such, a TF may act as a "catalyst" to mount a broad and acute response in cells that first sense the signal, while the recruited TF partners promote long-term adaptive behavior in the whole organism. This "Hit-and-Run" model likely has broad relevance, as TF perturbation studies across eukaryotes show small overlaps between TF-regulated and TF-bound genes, implicating transient TF-target binding. Here, we explore this "Hit-and-Run" model to suggest molecular mechanisms and its biological relevance. © 2015 The Authors. Bioessays published by WILEY Periodicals, Inc.

  10. Diffusion of Complete Streets policies Across US communities.

    Science.gov (United States)

    Moreland-Russell, Sarah; Eyler, Amy; Barbero, Colleen; Hipp, J Aaron; Walsh, Heidi

    2013-01-01

    Complete Streets policies guide planning in communities by making the transportation system accommodating to all users including vehicle drivers, pedestrians, and bicyclists, as well as those using public transportation. While the number of Complete Streets policies has increased over the past decade, no research has explored the factors attributing to the widespread diffusion of these policies. The purpose of this study was to apply concepts of the Diffusion of Innovation Theory to data related to Complete Streets policies in order to identify potential patterns and correlates. The main outcome of this study was policy adoption. Using the Diffusion of Innovation Theory and results from previous literature, we identified several factors that had the potential to affect the rate of Complete Streets policy diffusion: rural/urban status, state obesity rate, state funding for transportation, state obesity prevention funding, percentage of people who walk or bike to work in the state, presence of a state Complete Streets policy, and the number of bordering communities with Complete Streets policy. We used event history analysis as the main analysis method. Data from 49 community-level policies were analyzed, with a "community" defined as a city, a county, or a regional/Metropolitan Planning Organization. Three variables were significant predictors of Complete Streets policy adoption: state obesity rate (odds ratio [OR] = 1.465; confidence interval [CI] = 1.10-1.96) percentage of people who bike or walk to work in the state (OR = 1.726; CI = 1.069-2.79), and presence of a border community with a Complete Streets policy (OR = 3.859; CI = 1.084-13.742). Communities with Complete Streets policies varied in geographic and sociodemographic factors. Information about communities that are more likely to adopt a policy can be a tool for advocates and policy makers interested in this topic. Because adoption does not imply implementation, further research is needed to study

  11. Individuals with severely impaired vision can learn useful orientation and mobility skills in virtual streets and can use them to improve real street safety.

    Science.gov (United States)

    Bowman, Ellen Lambert; Liu, Lei

    2017-01-01

    Virtual reality has great potential in training road safety skills to individuals with low vision but the feasibility of such training has not been demonstrated. We tested the hypotheses that low vision individuals could learn useful skills in virtual streets and could apply them to improve real street safety. Twelve participants, whose vision was too poor to use the pedestrian signals were taught by a certified orientation and mobility specialist to determine the safest time to cross the street using the visual and auditory signals made by the start of previously stopped cars at a traffic-light controlled street intersection. Four participants were trained in real streets and eight in virtual streets presented on 3 projection screens. The crossing timing of all participants was evaluated in real streets before and after training. The participants were instructed to say "GO" at the time when they felt the safest to cross the street. A safety score was derived to quantify the GO calls based on its occurrence in the pedestrian phase (when the pedestrian sign did not show DON'T WALK). Before training, > 50% of the GO calls from all participants fell in the DON'T WALK phase of the traffic cycle and thus were totally unsafe. 20% of the GO calls fell in the latter half of the pedestrian phase. These calls were unsafe because one initiated crossing this late might not have sufficient time to walk across the street. After training, 90% of the GO calls fell in the early half of the pedestrian phase. These calls were safer because one initiated crossing in the pedestrian phase and had at least half of the pedestrian phase for walking across. Similar safety changes occurred in both virtual street and real street trained participants. An ANOVA showed a significant increase of the safety scores after training and there was no difference in this safety improvement between the virtual street and real street trained participants. This study demonstrated that virtual reality

  12. Hit Identification and Optimization in Virtual Screening: Practical Recommendations Based Upon a Critical Literature Analysis

    Science.gov (United States)

    Zhu, Tian; Cao, Shuyi; Su, Pin-Chih; Patel, Ram; Shah, Darshan; Chokshi, Heta B.; Szukala, Richard; Johnson, Michael E.; Hevener, Kirk E.

    2013-01-01

    A critical analysis of virtual screening results published between 2007 and 2011 was performed. The activity of reported hit compounds from over 400 studies was compared to their hit identification criteria. Hit rates and ligand efficiencies were calculated to assist in these analyses and the results were compared with factors such as the size of the virtual library and the number of compounds tested. A series of promiscuity, drug-like, and ADMET filters were applied to the reported hits to assess the quality of compounds reported and a careful analysis of a subset of the studies which presented hit optimization was performed. This data allowed us to make several practical recommendations with respect to selection of compounds for experimental testing, defining hit identification criteria, and general virtual screening hit criteria to allow for realistic hit optimization. A key recommendation is the use of size-targeted ligand efficiency values as hit identification criteria. PMID:23688234

  13. Hit identification and optimization in virtual screening: practical recommendations based on a critical literature analysis.

    Science.gov (United States)

    Zhu, Tian; Cao, Shuyi; Su, Pin-Chih; Patel, Ram; Shah, Darshan; Chokshi, Heta B; Szukala, Richard; Johnson, Michael E; Hevener, Kirk E

    2013-09-12

    A critical analysis of virtual screening results published between 2007 and 2011 was performed. The activity of reported hit compounds from over 400 studies was compared to their hit identification criteria. Hit rates and ligand efficiencies were calculated to assist in these analyses, and the results were compared with factors such as the size of the virtual library and the number of compounds tested. A series of promiscuity, druglike, and ADMET filters were applied to the reported hits to assess the quality of compounds reported, and a careful analysis of a subset of the studies that presented hit optimization was performed. These data allowed us to make several practical recommendations with respect to selection of compounds for experimental testing, definition of hit identification criteria, and general virtual screening hit criteria to allow for realistic hit optimization. A key recommendation is the use of size-targeted ligand efficiency values as hit identification criteria.

  14. Street Choice Logit Model for Visitors in Shopping Districts

    Science.gov (United States)

    Kawada, Ko; Yamada, Takashi; Kishimoto, Tatsuya

    2014-01-01

    In this study, we propose two models for predicting people’s activity. The first model is the pedestrian distribution prediction (or postdiction) model by multiple regression analysis using space syntax indices of urban fabric and people distribution data obtained from a field survey. The second model is a street choice model for visitors using multinomial logit model. We performed a questionnaire survey on the field to investigate the strolling routes of 46 visitors and obtained a total of 1211 street choices in their routes. We proposed a utility function, sum of weighted space syntax indices, and other indices, and estimated the parameters for weights on the basis of maximum likelihood. These models consider both street networks, distance from destination, direction of the street choice and other spatial compositions (numbers of pedestrians, cars, shops, and elevation). The first model explains the characteristics of the street where many people tend to walk or stay. The second model explains the mechanism underlying the street choice of visitors and clarifies the differences in the weights of street choice parameters among the various attributes, such as gender, existence of destinations, number of people, etc. For all the attributes considered, the influences of DISTANCE and DIRECTION are strong. On the other hand, the influences of Int.V, SHOPS, CARS, ELEVATION, and WIDTH are different for each attribute. People with defined destinations tend to choose streets that “have more shops, and are wider and lower”. In contrast, people with undefined destinations tend to choose streets of high Int.V. The choice of males is affected by Int.V, SHOPS, WIDTH (positive) and CARS (negative). Females prefer streets that have many shops, and couples tend to choose downhill streets. The behavior of individual persons is affected by all variables. The behavior of people visiting in groups is affected by SHOP and WIDTH (positive). PMID:25379274

  15. Street Choice Logit Model for Visitors in Shopping Districts

    Directory of Open Access Journals (Sweden)

    Ko Kawada

    2014-07-01

    Full Text Available In this study, we propose two models for predicting people’s activity. The first model is the pedestrian distribution prediction (or postdiction model by multiple regression analysis using space syntax indices of urban fabric and people distribution data obtained from a field survey. The second model is a street choice model for visitors using multinomial logit model. We performed a questionnaire survey on the field to investigate the strolling routes of 46 visitors and obtained a total of 1211 street choices in their routes. We proposed a utility function, sum of weighted space syntax indices, and other indices, and estimated the parameters for weights on the basis of maximum likelihood. These models consider both street networks, distance from destination, direction of the street choice and other spatial compositions (numbers of pedestrians, cars, shops, and elevation. The first model explains the characteristics of the street where many people tend to walk or stay. The second model explains the mechanism underlying the street choice of visitors and clarifies the differences in the weights of street choice parameters among the various attributes, such as gender, existence of destinations, number of people, etc. For all the attributes considered, the influences of DISTANCE and DIRECTION are strong. On the other hand, the influences of Int.V, SHOPS, CARS, ELEVATION, and WIDTH are different for each attribute. People with defined destinations tend to choose streets that “have more shops, and are wider and lower”. In contrast, people with undefined destinations tend to choose streets of high Int.V. The choice of males is affected by Int.V, SHOPS, WIDTH (positive and CARS (negative. Females prefer streets that have many shops, and couples tend to choose downhill streets. The behavior of individual persons is affected by all variables. The behavior of people visiting in groups is affected by SHOP and WIDTH (positive.

  16. Health policy making for street children: challenges and strategies.

    Science.gov (United States)

    Abdi, Fatemeh; Saeieh, Sara Esmaelzadeh; Roozbeh, Nasibeh; Yazdkhasti, Mansoureh

    2017-08-17

    Background The phenomenon of street children is a bio-psychological and social issue that not only harms children, but also endangers the health of a society. In line with the national programs for the development and promotion of street children's health in Iran, health policy making and essential strategies for this group of children will be presented in this paper. This paper will discuss the main issues and challenges of street children's health and, also, health policy and guidelines for this population. Methods In this review study, the keywords; street children, health, challenges, policy, and health policy making were searched through PubMed, SID, Iranmedex, World Health Organization (WHO), Emro, the Cochran Library, Medline and Google scholar to collect data. The search resulted in 84 related resources from which 48 cases that were more relevant to this research and covered the issue more comprehensively, were used. All data published during 2002-2015 have been included in this paper. Results Key concepts including street children and their health, health policy, strategies to improve the health of street children, health policy approaches for street children, the WHO's strategies, and social support program for street children must be considered in the health policy making processes for street children, as precise identification of the relevant information makes planning more effective in health policy making for this group of children. Conclusion The phenomenon of street children is a growing problem in the world and it has turned into a serious concern in many countries including Iran. The findings of this study can be used for identifying necessary measures in order to use research outcomes more effectively in policy making processes and reforming street children's health policies in Iran.

  17. In Pennsylvania Primary, AFT Hits the Streets

    Science.gov (United States)

    Hoff, David J.

    2008-01-01

    Every day, 14 retired teachers and other school employees arrive at the Philadelphia Federation of Teachers' headquarters and go to work for Hillary Rodham Clinton. The retirees--working with volunteers and union staff members from as far away as Alaska--are working to inform teachers' union members why the American Federation of Teachers (AFT)…

  18. Direct oral anticoagulants for treatment of HIT: update of Hamilton experience and literature review.

    Science.gov (United States)

    Warkentin, Theodore E; Pai, Menaka; Linkins, Lori-Ann

    2017-08-31

    Direct oral anticoagulants (DOACs) are attractive options for treatment of heparin-induced thrombocytopenia (HIT). We report our continuing experience in Hamilton, ON, Canada, since January 1, 2015 (when we completed our prospective study of rivaroxaban for HIT), using rivaroxaban for serologically confirmed HIT (4Ts score ≥4 points; positive platelet factor 4 [PF4]/heparin immunoassay, positive serotonin-release assay). We also performed a literature review of HIT treatment using DOACs (rivaroxaban, apixaban, dabigatran, edoxaban). We focused on patients who received DOAC therapy for acute HIT as either primary therapy (group A) or secondary therapy (group B; initial treatment using a non-DOAC/non-heparin anticoagulant with transition to a DOAC during HIT-associated thrombocytopenia). Our primary end point was occurrence of objectively documented thrombosis during DOAC therapy for acute HIT. We found that recovery without new, progressive, or recurrent thrombosis occurred in all 10 Hamilton patients with acute HIT treated with rivaroxaban. Data from the literature review plus these new data identified a thrombosis rate of 1 of 46 patients (2.2%; 95% CI, 0.4%-11.3%) in patients treated with rivaroxaban during acute HIT (group A, n = 25; group B, n = 21); major hemorrhage was seen in 0 of 46 patients. Similar outcomes in smaller numbers of patients were observed with apixaban (n = 12) and dabigatran (n = 11). DOACs offer simplified management of selected patients, as illustrated by a case of persisting (autoimmune) HIT (>2-month platelet recovery with inversely parallel waning of serum-induced heparin-independent serotonin release) with successful outpatient rivaroxaban management of HIT-associated thrombosis. Evidence supporting efficacy and safety of DOACs for acute HIT is increasing, with the most experience reported for rivaroxaban. © 2017 by The American Society of Hematology.

  19. Whose Bay Street? Competing Narratives of Nassau's City Centre

    Directory of Open Access Journals (Sweden)

    Nona Patara Martin

    2009-05-01

    Full Text Available Bay Street has always been at the centre of commercial, cultural and political life in the Bahama Islands. It also acts as a gateway for millions of tourists who come to Nassau, the Bahamian capital, via cruise ships every year. Not surprisingly, Bahamians and non-Bahamians have widely divergent impressions of Bay Street. The need to accommodate the tourists who are critical to the Bahamian economy has meant that Bay Street, despite its deep social significance for Bahamians, has increasingly become a tourist space. With reference to the ‘sense of place’ and place attachment literature, this paper traces the transformation of Bay Street and attempts to tease out the most obvious tensions between the Bay Street that Bahamians experience and Bay Street as a port of call.

  20. Alcohol in urban streetscapes: a comparison of the use of Google Street View and on-street observation

    Directory of Open Access Journals (Sweden)

    Chris Clews

    2016-05-01

    Full Text Available Abstract Background Alcohol-related harm is a major global health issue, and controls on alcohol marketing are one intervention utilized by governments. This study investigated the use of Google Street View (GSV as a novel research method for collecting alcohol-related data in the urban environment. Methods The efficacy of GSV and on-street observation by observer teams was compared by surveying 400 m stretches of 12 streets in Wellington, the capital city of New Zealand. Data on alcohol sale, alcohol-related advertising, health promotion materials, regulatory information and visible alcohol consumption were collected. Results A total of 403 retailers with evidence of alcohol sales and 1161 items of alcohol-related communication were identified in on-street observation. Of the latter, 1028 items (89 % were for alcohol marketing and 133 (11 % were for alcohol-related health promotion and alcohol regulation. GSV was found to be a less sensitive tool than on-street observation with only 50 % of the alcohol venues identified and 52 % of the venue-associated brand marketing identified. A high degree of inter-observer reliability was generally found between pairs of observers e.g., for the detection of alcohol retail venues the intra-class correlation coefficient (ICC was 0.93 (95 % CI: 0.78 to 0.98 for on-street observation and 0.85 (95 % CI: 0.49 to 0.96 for using GSV. Conclusions GSV does not seem suitable for the comprehensive study of the influences on alcohol consumption in the urban streetscape. However, it may still have value for large, static objects in the environment and be more time efficient than traditional on-street observation measures, especially when used to collect data across a wide geographical area. Furthermore, GSV might become a more useful research tool in settings with better image quality (such as more ‘footpath views’ and with more regularly updated GSV imagery.

  1. Efficiency Improvement of HIT Solar Cells on p-Type Si Wafers.

    Science.gov (United States)

    Wei, Chun-You; Lin, Chu-Hsuan; Hsiao, Hao-Tse; Yang, Po-Chuan; Wang, Chih-Ming; Pan, Yen-Chih

    2013-11-22

    Single crystal silicon solar cells are still predominant in the market due to the abundance of silicon on earth and their acceptable efficiency. Different solar-cell structures of single crystalline Si have been investigated to boost efficiency; the heterojunction with intrinsic thin layer (HIT) structure is currently the leading technology. The record efficiency values of state-of-the art HIT solar cells have always been based on n-type single-crystalline Si wafers. Improving the efficiency of cells based on p-type single-crystalline Si wafers could provide broader options for the development of HIT solar cells. In this study, we varied the thickness of intrinsic hydrogenated amorphous Si layer to improve the efficiency of HIT solar cells on p-type Si wafers.

  2. Mapping Cultural Ecosystem Services in Vilnius using Hot-Spot Analysis.

    Science.gov (United States)

    Pereira, Paulo; Depellegrin, Daniel; Egarter-Vigl, Lukas; Oliva, Marc; Misiune, Ieva; Keesstra, Saskia; Estebaranz, Ferran; Cerda, Artemi

    2017-04-01

    Cultural services in urban areas are very important to promote tourism activities and develop the economy. These activities are fundamental for the sustainability of the urban areas since can represent an important monetary source. However, one of the major threats to the sustainability of cultural services is the high amount of visitants that can lead to a degradation of the services provided (Depellegrin et al., 2016). Mapping the potential of cultural ecosystems services is fundamental to assess the capacity that the territory have to provide it. Previous works used land use classification to identify the ecosystem services potential, and revealed to be a good methodology to attribute to each type of land use a specific capacity (Burkhard et al., 2008). The objective of this work is to map the cultural services in Vilnius area using a hot-spot analysis. Ecosystem services potential was assessed using the matrix developed by Burkhard et al. (2009), which ranks ES capacity from 0= no capacity to 5=very high relevant capacity to a different land use type. The results showed that with the exception of Cultural Heritage ecosystem services that had a random pattern (Z-score=0.62, pTourism (Z-score=4.02, pReligious and Spiritual (Z-score=3.80, pTourism ecosystem services had the maximum spatial correlation at the distance of 5125.12 m, Landscape Aesthetics at 3495.70 m, Knowledge Systems at 5218.66 m, Religious and Spiritual at 3495.70 m, Cultural Heritage at 6746.17 m and Natural Heritage at 6205.82 m. This showed that the cultural services studied have a different spatial correlation. References Burkhard B, Kroll F, Müller F, Windhorst W. 2009. Landscapes' capacities to provide ecosystem services- a concept for land-cover based assessments. Landscape Online. 15, 1-22. Depellegrin, D.A., Pereira, P., Misiune, I., Egarter-Vigl, L. Mapping Ecosystem Services potential in Lithuania. International Journal of Sustainable Development and World Ecology, 23, 441-455.

  3. Computational Physics' Greatest Hits

    Science.gov (United States)

    Bug, Amy

    2011-03-01

    The digital computer, has worked its way so effectively into our profession that now, roughly 65 years after its invention, it is virtually impossible to find a field of experimental or theoretical physics unaided by computational innovation. It is tough to think of another device about which one can make that claim. In the session ``What is computational physics?'' speakers will distinguish computation within the field of computational physics from this ubiquitous importance across all subfields of physics. This talk will recap the invited session ``Great Advances...Past, Present and Future'' in which five dramatic areas of discovery (five of our ``greatest hits'') are chronicled: The physics of many-boson systems via Path Integral Monte Carlo, the thermodynamic behavior of a huge number of diverse systems via Monte Carlo Methods, the discovery of new pharmaceutical agents via molecular dynamics, predictive simulations of global climate change via detailed, cross-disciplinary earth system models, and an understanding of the formation of the first structures in our universe via galaxy formation simulations. The talk will also identify ``greatest hits'' in our field from the teaching and research perspectives of other members of DCOMP, including its Executive Committee.

  4. COPD: A stepwise or a hit hard approach?

    Directory of Open Access Journals (Sweden)

    A.J. Ferreira

    2016-07-01

    Full Text Available Current guidelines differ slightly on the recommendations for treatment of Chronic Obstructive Pulmonary Disease (COPD patients, and although there are some undisputed recommendations, there is still debate regarding the management of COPD. One of the hindrances to deciding which therapeutic approach to choose is late diagnosis or misdiagnosis of COPD. After a proper diagnosis is achieved and severity assessed, the choice between a stepwise or “hit hard” approach has to be made. For GOLD A patients the stepwise approach is recommended, whilst for B, C and D patients this remains debatable. Moreover, in patients for whom inhaled corticosteroids (ICS are recommended, a step-up or “hit hard” approach with triple therapy will depend on the patient's characteristics and, for patients who are being over-treated with ICS, ICS withdrawal should be performed, in order to optimize therapy and reduce excessive medications.This paper discusses and proposes stepwise, “hit hard”, step-up and ICS withdrawal therapeutic approaches for COPD patients based on their GOLD group. We conclude that all approaches have benefits, and only a careful patient selection will determine which approach is better, and which patients will benefit the most from each approach. Keywords: COPD, Stepwise, Hit hard, Step-up, ICS withdrawal, Bronchodilators, ICS

  5. Double-hit B-cell lymphomas

    NARCIS (Netherlands)

    Aukema, Sietse M.; Siebert, Reiner; Schuuring, Ed; van Imhoff, Gustaaf W.; Kluin-Nelemans, Hanneke C.; Boerma, Evert-Jan; Kluin, Philip M.

    2011-01-01

    In many B-cell lymphomas, chromosomal translocations are biologic and diagnostic hallmarks of disease. An intriguing subset is formed by the so-called double-hit (DH) lymphomas that are defined by a chromosomal breakpoint affecting the MYC/8q24 locus in combination with another recurrent breakpoint,

  6. Into a Mapping of Copenhagen Street Lighting 2014

    DEFF Research Database (Denmark)

    Bülow, Katja; Asp, Claus; Kongshaug, Jesper

    LED lighting is a new lighting component in urban Spaces. How does LED lighting change the visual experience of a street, how did it use to be and how will it become? The book presents a mapping method in which an overview map of light sources in the Copenhagen streets is combined with a video...... recording and a series of photos from a route, whick goes through different city parts and types of streets. The mapping is done in the crucial changing fase, in which the street lighting in Copenhagen is a mix of previously used light sources and LED....

  7. Are stripes beneficial? Dazzle camouflage influences perceived speed and hit rates.

    Directory of Open Access Journals (Sweden)

    Bettina von Helversen

    Full Text Available In the animal kingdom, camouflage refers to patterns that help potential prey avoid detection. Mostly camouflage is thought of as helping prey blend in with their background. In contrast, disruptive or dazzle patterns protect moving targets and have been suggested as an evolutionary force in shaping the dorsal patterns of animals. Dazzle patterns, such as stripes and zigzags, are thought to reduce the probability with which moving prey will be captured by impairing predators' perception of speed. We investigated how different patterns of stripes (longitudinal-i.e., parallel to movement direction-and vertical-i.e., perpendicular to movement direction affect the probability with which humans can hit moving objects and if differences in hitting probability are caused by a misperception of speed. A first experiment showed that longitudinally striped objects were hit more often than unicolored objects. However, vertically striped objects did not differ from unicolored objects. A second study examining the link between perceived speed and hitting probability showed that longitudinally and vertically striped objects were both perceived as moving faster and were hit more often than unicolored objects. In sum, our results provide evidence that striped patterns disrupt the perception of speed, which in turn influences how often objects are hit. However, the magnitude and the direction of the effects depend on additional factors such as speed and the task setup.

  8. POLE-LIKE STREET FURNITURE DECOMPOSTION IN MOBILE LASER SCANNING DATA

    OpenAIRE

    Li, F.; Oude Elberink, S.; Vosselman, G.

    2016-01-01

    Automatic semantic interpretation of street furniture has become a popular topic in recent years. Current studies detect street furniture as connected components of points above the street level. Street furniture classification based on properties of such components suffers from large intra class variability of shapes and cannot deal with mixed classes like traffic signs attached to light poles. In this paper, we focus on the decomposition of point clouds of pole-like street furniture. A nove...

  9. Influence of Running on Pistol Shot Hit Patterns.

    Science.gov (United States)

    Kerkhoff, Wim; Bolck, Annabel; Mattijssen, Erwin J A T

    2016-01-01

    In shooting scene reconstructions, risk assessment of the situation can be important for the legal system. Shooting accuracy and precision, and thus risk assessment, might be correlated with the shooter's physical movement and experience. The hit patterns of inexperienced and experienced shooters, while shooting stationary (10 shots) and in running motion (10 shots) with a semi-automatic pistol, were compared visually (with confidence ellipses) and statistically. The results show a significant difference in precision (circumference of the hit patterns) between stationary shots and shots fired in motion for both inexperienced and experienced shooters. The decrease in precision for all shooters was significantly larger in the y-direction than in the x-direction. The precision of the experienced shooters is overall better than that of the inexperienced shooters. No significant change in accuracy (shift in the hit pattern center) between stationary shots and shots fired in motion can be seen for all shooters. © 2015 American Academy of Forensic Sciences.

  10. The impact of Health Information Technology (I-HIT) Scale: the Australian results.

    Science.gov (United States)

    Cook, Robyn; Foster, Joanne

    2009-01-01

    One of role of the nurse in the clinical setting is that of co-ordinating communication across the healthcare team. On a daily basis nurses interact with the person receiving care, their family members, and multiple care providers thus placing the nurse in the central position with access to a vast array of information on the person. Through this nurses have historically functioned as "information repositories". With the advent of Health Information Technology (HIT) tools there is a potential that HIT could impact interdisciplinary communication, practice efficiency and effectiveness, relationships and workflow in acute care settings [1][3]. In 2005, the HIMSS Nursing Informatics Community developed the I-HIT Scale to measure the impact of HIT on the nursing role and interdisciplinary communication in USA hospitals. In 2007, nursing informatics colleagues from Australia, Finland, Ireland, New Zealand, Scotland and the USA formed a research collaborative to validate the I-HIT in six additional countries. This paper will discuss the background, methodology, results and implications from the Australian I-HIT survey of over 1,100 nurses. The results are currently being analyzed and will be presented at the conference.

  11. Street canyon ventilation control by proper planning and development

    Directory of Open Access Journals (Sweden)

    Balakin Vladimir Vasil'evich

    2014-05-01

    Full Text Available The objective of street canyon ventilation control in major streets is a tool of air pollution prevention in them, protection of housing areas from excessive wind or preservation and intensification of existing wind speed in case of insufficient ventilation. The maximum permissible concentration of car exhaust pollutants with wind speed within comfortable and permissible values by physiological and hygienic criteria, are ensured as from 40 to 70 % of thoroughfares in major cities. The dependence of air pollution level on wind speed is comparable to its dependence on traffic intensity and ratio of buildings height (H to street width. But one has to take into account that, if the wind blows across the street, vortices form within the street canyon, which results in higher concentration of car exhaust pollutants near the downwind buildings. The objective of this work is to find the functional dependences of wind speed in a major street on its width and density of buildings, and also to find out which street configurations are favorable for formation of closed air circulation within it, resulting in insufficient aeration. The experimental research was done on a site for large-scale modeling of built-up urban territory, using cup anemometers. The coefficients of dependence of wind speed within a street on the types of buildings and on the street width were obtained. Characteristics of street layouts for control of aeration were determined. Building density rates for maximizing or optimizing the wind speed were determined. Street layouts are considered where stable vortices form between the buildings. For example, vortices within the street canyon’s cross-section appear when buildings squarish in ground plan situated far apart are replaced by oblong ones with the minimum allowed intervals of 15 meters between them (for 5-storeyed buildings; or intervals equal to the buildings’ height, or where the buildings are long and close together. With

  12. Street children of India -- a glimpse.

    Science.gov (United States)

    Nigam, S

    1994-01-01

    In India, 90% of street children are working children with regular family ties who live with their families, but are on the streets due to poverty and their parents' unemployment. The remaining 10% are either working children with few family ties who view the streets as their homes or abandoned and neglected children with no family ties. The National Policy for Children established in 1974 emphasizes the provision of equal opportunities for the development to all children during their growing years. Policy stresses programs to maintain, educate, and train destitute children and orphans. Policy is also to protect children against neglect, cruelty, and exploitation, but this is only on paper. An UNICEF study found that almost 40,000 children die every day in developing countries, 25% of whom are in India. Studies in some major cities indicate that the street children in India are of moderate health status, suffering from various chronic diseases and undernourishment. They are deprived of all health programs, but seem to prefer government hospitals in case of dire need. Street children often have to pay for water. Almost 97% in Calcutta, 99% in Bangalore, and 90% in Madras reported having no access to toilet and bathing facilities; 83% in Kanpur, however, had access to such facilities. Nothing has been heard in recent years of the National Children's Board established in 1975. Apparently the board has gradually waned. Various schemes were planned in 1992 by the Union Welfare Ministry in association with UNICEF. Extending extra health facilities, establishing nutrition programs, providing vocational training, protecting children from abuse, distributing dry-food polypacks, providing night shelters, providing ration cards, and creating bathing and toilet facilities would go far in improving the quality of life and the future of street children in India.

  13. 75 FR 71744 - Fifth Street Finance Corp., et al.; Notice of Application

    Science.gov (United States)

    2010-11-24

    ... Street Finance Corp., et al.; Notice of Application November 18, 2010. AGENCY: Securities and Exchange... Street Finance Corp. (``Fifth Street''), Fifth Street Management LLC, Fifth Street Mezzanine Partners IV... regulated as a business development company (``BDC'') under the Act. Fifth Street is a specialty finance...

  14. Tolosa-Hunt Syndrome in Double-Hit Lymphoma

    Directory of Open Access Journals (Sweden)

    Prakash Peddi

    2015-01-01

    Full Text Available Tolosa-Hunt syndrome (THS is a painful condition characterized by hemicranial pain, retroorbital pain, loss of vision, oculomotor nerve paralysis, and sensory loss in distribution of ophthalmic and maxillary division of trigeminal nerve. Lymphomas rarely involve cavernous sinus and simulate Tolosa-Hunt syndrome. Here we present a first case of double-hit B cell lymphoma (DHL relapsing and masquerading as Tolosa-Hunt syndrome. The neurological findings were explained by a lymphomatous infiltration of the right Gasserian ganglion which preceded systemic relapse. As part of this report, the diagnostic criteria for Tolosa-Hunt syndrome and double-hit lymphoma are reviewed and updated treatment recommendations are presented.

  15. A Study on Evaluation for Street Space using AHP Method

    OpenAIRE

    小塚, みすず; 許, 彦; 川本, 義海; 本多, 義明

    2004-01-01

    Street space is an important public area which forms the framework of city space. In addition, from the view of the traffic functions, street space also plays a role to support people's activities performed in city. This paper examines the evaluations of street space among the cities of Fukui (Japan), Toyota (Japan) and Suzhou (China). Therefore, a questionnaire has been carried out and actual conditions of street space are grasped. In addition street functions were evaluated with the AHP met...

  16. "Street Love": How Street Life Oriented U. S. Born African Men Frame Giving Back to One Another and the Local Community

    Science.gov (United States)

    Payne, Yasser Arafat; Hamdi, Hanaa A.

    2009-01-01

    This Participatory Action Research (PAR) project worked with four active street life oriented U. S. born African men, to document how a community sample of street life oriented U. S. born African men between the ages of 16-65, frame and use "street life" as a Site of Resiliency (Payne, Dissertation, 2005; "Journal of Black Psychology" 34(1):3-31,…

  17. The (Street) Art of Resistance

    DEFF Research Database (Denmark)

    Awad, Sarah H.; Wagoner, Brady; Glaveanu, Vlad Petre

    2017-01-01

    This chapter focuses on the interrelation between resistance, novelty and social change We will consider resistance as both a social and individual phenomenon, a constructive process that articulates continuity and change and as an act oriented towards an imagined future of different communities....... In this account, resistance is thus a creative act having its own dynamic and, most of all, aesthetic dimension. In fact, it is one such visibly artistic form of resistance that will be considered here, the case of street art as a tool of social protest and revolution in Egypt. Street art is commonly defined...... in sharp contrast with high or fine art because of its collective nature and anonymity, its different kind of aesthetics, and most of all its disruptive, ‘anti-social’ outcomes. With the use of illustrations, we will argue here that street art is prototypical of a creative form of resistance, situated...

  18. 75 FR 62399 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee...

    Science.gov (United States)

    2010-10-08

    ... Technology; HIT Standards Committee Schedule for the Assessment of HIT Policy Committee Recommendations.... SUMMARY: Section 3003(b)(3) of the American Recovery and Reinvestment Act of 2009 mandates that the HIT Standards Committee develop a schedule for the assessment of policy recommendations developed by the HIT...

  19. HIT-6 and MIDAS as measures of headache disability in a headache referral population.

    Science.gov (United States)

    Sauro, Khara M; Rose, Marianne S; Becker, Werner J; Christie, Suzanne N; Giammarco, Rose; Mackie, Gordon F; Eloff, Arnoldas G; Gawel, Marek J

    2010-03-01

    The objective of this study was to compare the headache impact test (HIT-6) and the migraine disability assessment scale (MIDAS) as clinical measures of headache-related disability. The degree of headache-related disability is an important factor in treatment planning. Many quality of life and headache disability measures exist but it is unclear which of the available disability measures is the most helpful in planning and measuring headache management. We compared HIT-6 and MIDAS scores from 798 patients from the Canadian Headache Outpatient Registry and Database (CHORD). Correlation and regression analyses were used to examine the relationships between the HIT-6 and MIDAS total scores, headache frequency and intensity, and Beck Depression Inventory (BDI-II) scores. A positive correlation was found between HIT-6 and MIDAS scores (r = 0.52). The BDI-II scores correlated equally with the HIT-6 and the MIDAS (r = 0.42). There was a non-monotonic relationship between headache frequency and the MIDAS, and a non-linear monotonic relationship between headache frequency and the HIT-6 (r = 0.24). The correlation was higher between the intensity and the HIT-6 scores (r = 0.46), than MIDAS (r = 0.26) scores. Seventy-nine percent of patients fell into the most severe HIT-6 disability category, compared with the 57% of patients that fell into the most severe MIDAS disability category. Significantly more patients were placed in a more severe category with the HIT-6 than with the MIDAS (McNemar chi-square = 191 on 6 d.f., P MIDAS appear to measure headache-related disability in a similar fashion. However, some important differences may exist. Headache intensity appears to influence HIT-6 score more than the MIDAS, whereas the MIDAS was influenced more by headache frequency. Using the HIT-6 and MIDAS together may give a more accurate assessment of a patient's headache-related disability.

  20. Street children: “Running from” or “running to”?

    Directory of Open Access Journals (Sweden)

    J. le Roux

    1997-03-01

    Full Text Available The street child phenomenon presents a complex issue resulting from a diversity of integrated factors. The problem should therefore preferably be explained and addressed holistically. A search of available literature on street children clearly indicates that street children per se are not the primary problem. The phenomenon o f street children is merely a symptom of a problem underlying the intolerable situation of these children's family and community lives. In this article it is explained that the street child phenomenon is thus symptomatic of contemporary twentieth century conditions. "Running from " and “running to " are in fact intereffective tendencies or reactions to a complicated polarised society: two sides of a common coin.

  1. Designing safe and inclusive streets in India | CRDI - Centre de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    17 nov. 2016 ... Safe streets play a crucial role in enabling livelihoods, mobility, and access to services. In fast-growing Indian cities such as Ahmedabad, streets are also the site of conflict. With incomes and vehicle ownership on the rise, traffic has replaced people as the central point of street design. Vehicle-focused street ...

  2. School Me, School Me Not, Street Me, Street Me Not…

    DEFF Research Database (Denmark)

    Gravesen, David Thore; Frostholm, Peter Hornbæk

    School Me, School Me Not, Street Me, Street Me Not… (1099) David Thore Gravesen, Peter Hornbæk Frostholm ECER 2016, 14. Communities, Families and Schooling in Educational Research, Session: 14 SES 10 A When picking leaves of a marguerite, whilst doing the “she loves me, she loves me not” game, you....... Obviously, the skaters attend the site to skate. But also other, more vulnerable groupings, use the site to socialize, meet peers and perhaps escape an unreliable and risky family arena. One particular group, the self-named Thugz, primarily formed around a number of young boys with non-Danish ethnic...... milieu. With a criminal gang-like behavior (Hoeben & Weerman 2013; Hviid 2007; Rasmussen 2012) involving petty crime and violence, one would think the group members would be indifferent towards their schooling and future careers. This was not the case. The informants proved to be very aware...

  3. Improving urban visibility through fractal analysis of street edges: The case of John Evans Atta Mills High Street in Accra, Ghana

    Directory of Open Access Journals (Sweden)

    R.A. Oppong

    2017-06-01

    Full Text Available Streets are a representation of cities, and the image of a city is a reflection of its home country. Although attempts to ensure harmonious spatial and environmental development in Ghanaian settlements date back to the colonial era, these efforts have minimal physical manifestation in the urban fabric of the city of Accra. The Independence Arch of Ghana, an important landmark in the urban fabric and history of Accra, lacks the striking vista and approach it deserves. This paper introduces the use of fractal analysis of street edges to understand the characteristics of the John Evans Atta Mills (JEAM High Street for developing recommendations to improve visibility along its stretch and the overall image of the city. The box-counting method with visual survey was used in research. The pertinent questions this paper seeks to address are as follows: What factors affect the visibility and imageability of JEAM High Street? What design aspects should be considered to improve urban visibility along JEAM High Street? What is the link of fractals to urban design and architecture? The paper recommends various design considerations and qualities to improve the urban visibility and imageability of JEAM High Street.

  4. Diversity of contexts in drug use among street adolescents.

    Science.gov (United States)

    Goncalves de Moura, Yone; van der Meer Sanchez, Zila; Noto, Ana Regina

    2010-09-01

    In this study we aimed to investigate through ethnographic methods the different contexts of drug use by street adolescents in Sao Paulo, Brazil. Participant observations and semistructured interviews were performed at 11 major points of adolescent concentration in the streets of the city and in 10 care institutions. The sample was composed of 17 adolescents between 12 and 17 years of age. Data showed diverse patterns of drug use distributed by geographic situation and street circumstances. Observations were grouped into three main contexts: (a) immersion: greater intensity of drug use associated with greater involvement in the street culture; (b) surface: less drug use associated with family closeness; and (c) alternative-migratory: greater involvement with drug trafficking and prostitution associated with less family closeness and street culture. The drug use patterns varied in accordance with the diversity of street situations. Therefore, the peculiarities of each context should be taken into consideration in the development of social/ health policies.

  5. THE DEVELOPMENT OF STREET PATTERNS IN ISRAELI CITIES

    Directory of Open Access Journals (Sweden)

    Itzhak OMER

    2015-12-01

    Full Text Available Street patterns of Israeli cities were investigated by comparing three time periods of urban development: (I the late 19th century until the establishment of the state of Israel in 1948; (II 1948 until the 1980s; and (III the late 1980s until the present. These time periods are related respectively to the pre-modern, modern and late-modern urban planning approach. Representative urban street networks were examined in selected cities by means of morphological analysis of typical street pattern properties: curvature, fragmentation, connectivity, continuity and differentiation. The study results reveal significant differences between the street patterns of the three examined periods in the development of cities in Israel. The results show clearly the gradual trends in the intensification of curvature, fragmentation, complexity and hierarchical organization of street networks as well as the weakening of the network's internal and external connectivity. The implications of these changes on connectivity and spatial integration are discussed with respect to planning approaches.

  6. THE DEVELOPMENT OF STREET PATTERNS IN ISRAELI CITIES

    Directory of Open Access Journals (Sweden)

    Itzhak OMER

    2016-07-01

    Full Text Available Street patterns of Israeli cities were investigated by comparing three time periods of urban development: (I the late 19th century until the establishment of the state of Israel in 1948; (II 1948 until the 1980s; and (III the late 1980s until the present. These time periods are related respectively to the pre-modern, modern and late-modern urban planning approach. Representative urban street networks were examined in selected cities by means of morphological analysis of typical street pattern properties: curvature, fragmentation, connectivity, continuity and differentiation. The study results reveal significant differences between the street patterns of the three examined periods in the development of cities in Israel. The results show clearly the gradual trends in the intensification of curvature, fragmentation, complexity and hierarchical organization of street networks as well as the weakening of the network's internal and external connectivity. The implications of these changes on connectivity and spatial integration are discussed with respect to planning approaches.

  7. Does ′heparin-induced thrombocytopenia′ hit our minds?

    Directory of Open Access Journals (Sweden)

    Arun R Thangavel

    2016-01-01

    Full Text Available Unfractionated heparin is a widely used drug to prevent deep vein thrombosis and pulmonary emboli in patients at risk. With the advent of newer anticoagulants having lesser side effects, its use has diminished but not out of service. Here, we report a case of deep venous thrombosis, in a patient on prophylactic dose of heparin, which was later found to be a manifestation of heparin-induced thrombocytopenia (HIT. Thrombosis in the presence of heparin prophylaxis should be considered as HIT rather than a failure of anticoagulation.

  8. Nedley Depression Hit Hypothesis: Identifying Depression and Its Causes.

    Science.gov (United States)

    Nedley, Neil; Ramirez, Francisco E

    2016-11-01

    Depression is often diagnosed using the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5) criteria. We propose how certain lifestyle choices and non-modifiable factors can predict the development of depression. We identified 10 cause categories (hits or "blows" to the brain) and theorize that four or more active hits could trigger a depression episode. Methods. A sample of 4271 participants from our community-based program (70% female; ages 17-94 years) was assessed at baseline and at the eighth week of the program using a custom test. Ten cause categories were examined as predictors of depression are (1) Genetic, (2)Developmental, (3)Lifestyle, (4)Circadian Rhythm, (5)Addiction, (6)Nutrition, (7)Toxic, (8)Social/Complicated Grief, (9)Medical Condition, and (10)Frontal Lobe. Results. The relationship between the DSM-5 score and a person having four hits categories in the first program week showed a sensitivity of 89.98 % (95% CI: 89.20 % - 90.73%), specificity 48.84% (CI 45.94-51.75) and Matthew Correlation Coefficient (MCC) .41 . For the eight-week test, the results showed a sensitivity 83.6% (CI 81.9-85.5), specificity 53.7% (CI 51.7-55.6) and MCC .38. Overall, the hits that improved the most from baseline after the eighth week were: Nutrition (47%), Frontal lobe (36%), Addiction (24%), Circadian rhythm (24%), Lifestyle (20%), Social (12%) and Medical (10%). Conclusions. The Nedley four-hit hypothesis seems to predict a depressive episode and correlates well with the DSM-5 criteria with good sensitivity and MCC but less specificity. Identifying these factors and applying lifestyle therapies could play an important role in the treatment of depressed individuals.

  9. Socio - demographic characteristics of child street vendors in Nnewi ...

    African Journals Online (AJOL)

    Background: Involvement of children in street trading is inimical, contrary to the Rights of the Child, and threatens holistic child development. Objective: To describe the sociodemographic characteristics of child street vendors in Nnewi. Method: A cross-sectional questionnaire survey of children selling wares on the streets of ...

  10. Socio-demographic characteristics of street children in rural ... - Ibadan

    African Journals Online (AJOL)

    15.0%), part-time driving (9.5%) and car washing (5.0%) were the commonest types of work. Of those still schooling, 41.6% had no form of part-time work on the streets. None of the street children lived on the street with 65% still living with parents.

  11. Space Livability of Street Vendors in Simpang Lima Public Space, Semarang

    Science.gov (United States)

    Widjajanti, R.; Wahyono, H.

    2018-02-01

    Street vendors in Semarang have been growing rapidly and uncontrolled. They always use public space such as public roads, sidewalks, parks and fields as trading locations. The street vendors’ activities in the public space are considered as the cause of declining on environmental quality and aesthetics of the city. All these years, the government often evicted the street vendors than organized and provides adequate space for them. As one of the actual urban activities, the street vendors’ activities should be accommodated by the government and the location for them is managed in the urban spatial plan. Street vendors need spaces which livable and suitable to their activities’ requirements, has a relationship with users (street vendors’ doers and consumers) and the activities of street vendors themselves. Research on the aspect of space for street vendors is still less in quantity, whereas space for them is an urgent matter for the government in managing their activities. This study aims to identify the livability of space based on the street vendors’ behavior in their location. This research used descriptive quantitative method with questionnaires and GIS as the mapping tool for street vendors’ location. The result of the research shows that the livability of street vendor space is based on the activity of street vendors (type of merchandise, trading places’ size, trade place assessment, space dimension, trading time, duration and period) and space conditions (access, natural elements, safety and parking space).

  12. [Street Outreach Offices: visibility, invisibility, and enhanced visibility].

    Science.gov (United States)

    Hallais, Janaína Alves da Silveira; Barros, Nelson Filice de

    2015-07-01

    This article discusses care for street people from a socio-anthropological perspective, using participant observation conducted with a team from a street outreach project. Based on observations, street people are historically viewed as marginal and rarely obtain access to health services, thus making them invisible to the Brazilian Unified National Health System. Brazil's National Policy for the Homeless provides for their access to health care, but such care is not always guaranteed in practice, because health services and professionals have little experience in dealing with homeless persons. The study concludes that enhanced visibility is needed to ensure care for people living on the street, establishing a therapeutic bond that deconstructs stigmatizing practice.

  13. A social work study on family patterns and street children

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Iravani

    2014-06-01

    Full Text Available This paper presents a social work study on relationship between various family characteristics and street children in rural area as well as city of Esfahan, Iran. The proposed study selects a sample of 150 street children, 75 from city and 75 from rural area, and using some statistical tests verifies the effects of three factors including family income, place of residency and family size on street children. The results indicate that the city residence had more street children than rural residence did. In addition, there was a meaningful difference between the number of street children in low-income families and high-income families. Finally, the survey results indicate that big size families more likely suffered from street children than low size families did.

  14. Risk behaviour of street children in Colombo.

    Science.gov (United States)

    Senaratna, B C V; Wijewardana, B V N

    2012-09-01

    Sri Lankan street children live in insecure and disadvantaged environments and have disrupted and poorly functioning families resulting in their poor socialisation. In this backdrop they are at high risk of adopting delinquent and antisocial behaviour and becoming victims of abuse. Despite recognition of this as a social problem, an in-depth exploration of their behaviour and its correlates has not been attempted. To describe risk behaviour among street children in Colombo city and the determinants of such behaviour. A cross sectional qualitative study in Colombo Fort, Pettah, Slave Island, and Maradana areas was conducted using focus group discussions (FGDs) with street children and semi-structured interviews (SSIs) with street children and key informants in their environment. Data generated were used to profile 283 children identified through referral sampling. An observation study was conducted to validate data generated through FGDs and SSIs. Semi-structured questionnaires, a moderator guide, an interviewer-administered questionnaire, and an observational checklist were used for SSIs, FGDs, profiling, and observational study, respectively. Majority of street children were boys and were aged 14 years or less. Nearly 18% lived alone without a guardian. Two thirds had never enrolled in a school. Many children were used for begging, neglecting their health vulnerabilities. Occupational risk behaviour included heavy manual labour, transportation and sale of illicit alcohol and narcotics, robbing/pick-pocketing, commercial sex work, and pimping. Recreational risk behaviour included abuse of alcohol/narcotics, smoking, sexual promiscuity, and patronising commercial sex workers. Increased awareness and strategies are required to minimise threats to street children and society.

  15. Analyzing Thermal Characteristics of Urban Streets Using a Thermal Imaging Camera: A Case Study on Commercial Streets in Seoul, Korea

    Directory of Open Access Journals (Sweden)

    Sugie Lee

    2018-02-01

    Full Text Available Due to continuing city growth and global warming over the past decades, urban heat island (UHI effects, referring to the phenomena wherein the ambient air temperatures in cities are higher than those in rural areas, have become a serious threat to urban populations. Impervious surfaces, buildings with low-albedo materials, and a lack of vegetated areas are the major causes of poor urban thermal environments, particularly during the summer. Previous research has focused primarily on the thermal characteristics of individual building units. Few studies consider the impact of the street-scale thermal environments on the surface temperature, which affects pedestrian thermal comfort. The purpose of this study is to analyze the thermal characteristics of various physical elements on urban streets using thermal imaging cameras, and present policy implications for improving pedestrian thermal comfort. This study examines street-scale thermal environments of three major commercial streets: Garosu road, Serosu road, and Narosu road, in Seoul, Korea. This study conducted field measurements both during the day and the night in June 2017 in order to investigate changes in the urban surface temperatures across time. The results show that street trees are the most effective mitigation element for reducing surface temperatures. With regard to building use types, the highest surface temperatures are typically measured near restaurant buildings. Building façades that are dark-colored or partially covered with a metal contribute to high surface temperatures. Similarly, the temperatures of artificial turf or wooden decks on urban streets are also significantly high during the daytime. The thermal characteristics of various urban street elements should be considered to reduce the surface temperature and mitigate the urban heat island effect.

  16. 77 FR 57567 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-09-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  17. 77 FR 50690 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-08-22

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  18. 77 FR 15760 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-03-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  19. 76 FR 39108 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-07-05

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS ACTION: Notice of... the public. Name of Committee: HIT Policy Committee. General Function of the Committee: to provide...

  20. 77 FR 37407 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-06-21

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  1. 76 FR 22397 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-04-21

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  2. 77 FR 22787 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-04-17

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  3. 77 FR 27459 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-05-10

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: to provide recommendations to...

  4. 76 FR 28783 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-05-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  5. 76 FR 79684 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-12-22

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  6. 77 FR 73660 - HIT Policy Committee Advisory Meetings; Notice of Meetings

    Science.gov (United States)

    2012-12-11

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meetings; Notice of Meetings AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  7. 77 FR 28881 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-05-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: to provide recommendations to...

  8. 76 FR 46298 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-08-02

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  9. 77 FR 65691 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-10-30

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  10. 76 FR 70455 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-11-14

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: to provide recommendations to...

  11. 77 FR 2727 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-01-19

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  12. 76 FR 14975 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-03-18

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: to provide recommendations to...

  13. 76 FR 50734 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-08-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  14. 76 FR 55912 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2011-09-09

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... the public. Name of Committee: HIT Policy Committee. General Function of the Committee: To provide...

  15. 77 FR 41788 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2012-07-16

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of... of Committee: HIT Policy Committee. General Function of the Committee: To provide recommendations to...

  16. Competition for the Elements of the City Environment for Irkutsk’s Public Spaces: Street Furniture, Street Design

    Directory of Open Access Journals (Sweden)

    Tatyana Danilova

    2016-10-01

    Full Text Available The article reviews the contest «Street furniture. Street design», which was held this summer by manufacturing company «PalpNord», International research laboratory of study and design of the urban environment «Urban Planning School» and the Union of Architects of Russia. The winners and their projects are also listed in the article.

  17. Mapping Urban Land Use at Street Block Level Using OpenStreetMap, Remote Sensing Data, and Spatial Metrics

    Directory of Open Access Journals (Sweden)

    Taïs Grippa

    2018-06-01

    Full Text Available Up-to-date and reliable land-use information is essential for a variety of applications such as planning or monitoring of the urban environment. This research presents a workflow for mapping urban land use at the street block level, with a focus on residential use, using very-high resolution satellite imagery and derived land-cover maps as input. We develop a processing chain for the automated creation of street block polygons from OpenStreetMap and ancillary data. Spatial metrics and other street block features are computed, followed by feature selection that reduces the initial datasets by more than 80%, providing a parsimonious, discriminative, and redundancy-free set of features. A random forest (RF classifier is used for the classification of street blocks, which results in accuracies of 84% and 79% for five and six land-use classes, respectively. We exploit the probabilistic output of RF to identify and relabel blocks that have a high degree of uncertainty. Finally, the thematic precision of the residential blocks is refined according to the proportion of the built-up area. The output data and processing chains are made freely available. The proposed framework is able to process large datasets, given that the cities in the case studies, Dakar and Ouagadougou, cover more than 1000 km2 in total, with a spatial resolution of 0.5 m.

  18. SHIELD-HIT12A - a Monte Carlo particle transport program for ion therapy research

    DEFF Research Database (Denmark)

    Bassler, Niels; Hansen, David Christoffer; Lühr, Armin

    2014-01-01

    . We experienced that new users quickly learn to use SHIELD-HIT12A and setup new geometries. Contrary to previous versions of SHIELD-HIT, the 12A distribution comes along with easy-to-use example files and an English manual. A new implementation of Vavilov straggling resulted in a massive reduction......Abstract. Purpose: The Monte Carlo (MC) code SHIELD-HIT simulates the transport of ions through matter. Since SHIELD-HIT08 we added numerous features that improves speed, usability and underlying physics and thereby the user experience. The “-A” fork of SHIELD-HIT also aims to attach SHIELD....... It supports native formats compatible with the heavy ion treatment planning system TRiP. Stopping power files follow ICRU standard and are generated using the libdEdx library, which allows the user to choose from a multitude of stopping power tables. Results: SHIELD-HIT12A runs on Linux and Windows platforms...

  19. Hair geochemical composition of children from Vilnius kindergartens as an indicator of environmental conditions.

    Science.gov (United States)

    Taraškevičius, Ričardas; Zinkutė, Rimantė; Gedminienė, Laura; Stankevičius, Žilvinas

    2017-05-23

    The research is based on analysis data of Cr, Cu, Mn, Ni, V, Zn (metals) and S in the hair of 47 girls and 63 boys from eight Vilnius kindergartens and the distribution pattern of high metal concentrations and bioavailability in snow-cover dust, also dust samples from vents of characteristic pollution sources. The kindergartens were selected according to topsoil total contamination index and dust-related indices. Significantly higher Cu, Mn, Ni and Zn concentrations in the hair of girls (means are 1.1, 1.9, 1.3, 1.2 times higher) and the differences between hair of genders according to inter-element correlation and clustering were found. Analysis of Spearman correlation coefficients between metal concentrations in hair of each gender and dust metal concentrations or metal loading rates at their residence sites revealed that for Mn, Cu and Zn, they are insignificant, while for Cr, Ni, Pb and V, they are mainly significant positive (except V in female hair). The correlation of the contents of Cr, Ni and V in dust with respective concentrations in hair was more significant for boys (p polluted kindergartens in comparison with control. It was concluded that relationship between metal concentrations in hair and dust-related indices is more expressed for children's residence sites than for their kindergarten sites. The gender-based grouping and site-by-site study design are recommended in the studies of reflection of environmental exposure in hair.

  20. 75 FR 21629 - HIT Policy Committee Advisory Meeting; Notice of Meeting

    Science.gov (United States)

    2010-04-26

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the National Coordinator for Health Information Technology HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Policy Committee...

  1. Hiding in Plain Sight: Street artists online

    Directory of Open Access Journals (Sweden)

    Kim Barbour

    2013-10-01

    Full Text Available Identity and privacy concerns related to social media are the subject of widespread academic enquiry and mass media reporting. Although in most circumstances academic research tends to present identity play and online self­presentation as positive, media reporting in Australia makes much of the risks of identity theft, privacy breaches and online predators. This research explores the phenomenological experience of creating an online persona, focusing particularly on street artists. For street artists, the threat of unwanted exposure has to be balanced with the positive implications of sharing their creative work outside its geographical and temporal constraints. I argue that street artists use complex persona­creation strategies in order to both protect and promote themselves. The two street artists discussed in this article experience their engagement with social media and digital networks in ways that offer new insight into the opportunities and problems associated with the presentation of a persona online.

  2. Evaluation of the Street Pollution Model OSPM for Measurements at 12 Streets Stations Using a Newly Developed and Freely Available Evaluation Tool

    DEFF Research Database (Denmark)

    Ketzel, Matthias; Jensen, Steen Solvang; Brandt, Jørgen

    2012-01-01

    In the present work, the Operational Street Pollution Model (OSPM) has been evaluated in comparison with continuous half-hourly measurements over a multi-year period for five permanent street monitor stations that constitute part of the Danish Air Quality Monitoring Programme as well as with pass......In the present work, the Operational Street Pollution Model (OSPM) has been evaluated in comparison with continuous half-hourly measurements over a multi-year period for five permanent street monitor stations that constitute part of the Danish Air Quality Monitoring Programme as well...... the observations well, especially for the most recent years, while for NO2 the model over-predicts in two cases. The explanation for this over-prediction is believed to be uncertainties in the traffic or emission input data, but also in model parameters, and the representativeness of the urban background data may....... OSPM calculations for nine streets with passive sampler measurements were conducted as ‘blind test’ i.e. without knowing the measured values. OSPM calculations were in good agreement with the measurements for seven out of nine street sections. Refinements of the input data lead to a significant...

  3. Exposure to maltreatment and urban violence in children working on the streets in São Paulo, Brazil: factors associated with street work

    Directory of Open Access Journals (Sweden)

    Andrea F. Mello

    2014-09-01

    Full Text Available Objective: To quantitatively study the exposure to childhood maltreatment and urban violence in children from families with at least one child working on the streets and to investigate the relationship between these factors and street work. Methods: Families who participated in a nongovernmental organization (NGO program to eliminate child labor were included. Data concerning sociodemographic characteristics, punishment methods used in the family environment against the children, five types of abuse and neglect perpetrated by the caregivers, urban violence exposure and family functioning were collected. Results: The sample included 126 children who were working on the streets and 65 siblings who were not working on the streets. Caregivers reported high levels of severe physical punishment. The children reported high levels of abuse and neglect, and high levels of urban violence exposure. The families showed a predominance of dysfunctional and unsatisfactory relationships. A multiple logistic regression model showed that age older than 12 years and severe physical punishment at home were associated with street work. Conclusion: Interventions to decrease the risk of child street work should be family-focused and should aim to reduce violence in the family environment.

  4. Occupy Wall Street

    DEFF Research Database (Denmark)

    Jensen, Michael J.; Bang, Henrik

    2013-01-01

    This article analyzes the political form of Occupy Wall Street on Twitter. Drawing on evidence contained within the profiles of over 50,000 Twitter users, political identities of participants are characterized using natural language processing. The results find evidence of a traditional...

  5. [Who told you to grow old and live on the streets?].

    Science.gov (United States)

    Brêtas, Ana Cristina Passarella; Marcolan, João Fernando; Rosa, Anderson da Silva; Fernandes, Flávia Saraiva Leão; Raizer, Milena Veiga

    2010-06-01

    This qualitative case study is part of another study: Aging, health and work. The objective of this excerpt was to identify the meaning of aging on the streets for the elderly living on the street. The subjects' statements were analyzed under the light of the following themes: history of aging and history of life on the streets. It was understood that the streets are usually a hostile environment for the elderly. It does not guarantee the basic life conditions, affecting the mental health of people who are forced to live on the streets, particularly the elderly. The street does not offer any way out and, together with to the life conditions of the elderly living on the streets leads to the gradual loss of self-esteem, significantly affecting self-care. In addition to these issues, we found that compromised functional capacity puts the life/survival of the elderly living on the streets at risk.

  6. Can activity support influence image of a street?

    Science.gov (United States)

    Tamiami Fachrudin, Hilma

    2018-03-01

    Activity support may affect the formation of the image of a corridor and street. Form, place, and character of activity support in an area will have the function attraction and usefulness of its activities. The aim of this research is to analyze how the influence of activity support on the image of a street, in this case, Dr.Mansyur street which located in front of Universitas Sumatera Utara. Along the street, there are various activities that conducted from morning until evening. The method used is a quantitative method with observation and questionnaire techniques. A population of this study is visitors and students of architecture department from Universitas Sumatera Utara (USU) with sample number is 100 respondents for visitors and 100 respondents for students. Independent variables are activity support factors that consist of the type of activity, form, color, dimension, material, position and lighting. The dependent variable is imageability by [1]. Data were analyzed using logistic regression analysis. The results show that activity support influences image Dr. Mansyur street that has an image as a campus and culinary area and easy to identify.

  7. Characteristics of street children in Cameroon: A cross-sectional study

    Science.gov (United States)

    Cumber, Samuel N.

    2016-01-01

    Introduction The issue of street children is one of the global social problems rising in low- and middle-income countries. These children are vulnerable, but because of a lack of sufficient information, it is very difficult for stakeholders to address their plight in Cameroon. Aim To examine the situation and characteristics of street children in three Cameroonian cities. Objectives To describe the demographic, socio-economic and behavioural profiles of street children. To identify challenges of street children and to compare the results from the three cities on account of their different settings, cultural history and challenges. Materials and methods The study was an analytical cross-sectional survey conducted through researcher-administered questionnaires to 399 street children (homeless for at least a month), in three Cameroonian cities from 1 January 2015 to 30 March 2015. Results The majority of the participants were boys, more than 70% were homeless for less than 12 months and poverty was found to be the most common reason for being on the street. Most of the participants earned less than 500CFA francs (USD 0.85), with many of them resorting to begging, drug abuse, sex work and other risky behaviours. Only two of the respondents (0.5%) regarded the public attitude towards them as supportive. Conclusion As children roam the streets in search of shelter, food and other basic needs, their future hangs in the balance. Understanding the plight of street children highlights the need for immediate design and implementation of intervention strategies to prevent children from living in the streets and assist those who have become street children. PMID:28155316

  8. Multi-hit time-to-amplitude CAMAC module (MTAC)

    International Nuclear Information System (INIS)

    Kang, H.

    1980-10-01

    A Multi-Hit Time-to-Amplitude Module (MTAC) for the SLAC Mark III drift chamber system has been designed to measure drift time by converting time-proportional chamber signals into analog levels, and converting the analog data by slow readout via a semi-autonomous controller in a CAMAC crate. The single width CAMAC module has 16 wire channels, each with a 4-hit capacity. An externally generated common start initiates an internal precision ramp voltage which is then sampled using a novel shift register gating scheme and CMOS sampling switches. The detailed design and performance specifications are described

  9. Improvements to the ion Doppler spectrometer diagnostic on the HIT-SI experiments

    Science.gov (United States)

    Hossack, Aaron; Chandra, Rian; Everson, Chris; Jarboe, Tom

    2018-03-01

    An ion Doppler spectrometer diagnostic system measuring impurity ion temperature and velocity on the HIT-SI and HIT-SI3 spheromak devices has been improved with higher spatiotemporal resolution and lower error than previously described devices. Hardware and software improvements to the established technique have resulted in a record of 6.9 μs temporal and ≤2.8 cm spatial resolution in the midplane of each device. These allow Ciii and Oii flow, displacement, and temperature profiles to be observed simultaneously. With 72 fused-silica fiber channels in two independent bundles, and an f/8.5 Czerny-Turner spectrometer coupled to a video camera, frame rates of up to ten times the imposed magnetic perturbation frequency of 14.5 kHz were achieved in HIT-SI, viewing the upper half of the midplane. In HIT-SI3, frame rates of up to eight times the perturbation frequency were achieved viewing both halves of the midplane. Biorthogonal decomposition is used as a novel filtering tool, reducing uncertainty in ion temperature from ≲13 to ≲5 eV (with an instrument temperature of 8-16 eV) and uncertainty in velocity from ≲2 to ≲1 km/s. Doppler shift and broadening are calculated via the Levenberg-Marquardt algorithm, after which the errors in velocity and temperature are uniquely specified. Axisymmetric temperature profiles on HIT-SI3 for Ciii peaked near the inboard current separatrix at ≈40 eV are observed. Axisymmetric plasma displacement profiles have been measured on HIT-SI3, peaking at ≈6 cm at the outboard separatrix. Both profiles agree with the upper half of the midplane observable by HIT-SI. With its complete midplane view, HIT-SI3 has unambiguously extracted axisymmetric, toroidal current dependent rotation of up to 3 km/s. Analysis of the temporal phase of the displacement uncovers a coherent structure, locked to the applied perturbation. Previously described diagnostic systems could not achieve such results.

  10. Playing With the City: Street Art and Videogames

    OpenAIRE

    Vazques Marquez, Israel; Pajares Tosca, Susana

    2017-01-01

    In this paper we introduce and describe the phenomenon of videogame street art as a specific kind of street art. We consider its materiality and significance, and conceptualize it in the light of a double manifestation of play: the playful appropriation of the city by the artist and the fact that street art encapsulates the act of playing videogames in a visual form. Digital play spills out of our computer screens and occupies the urban space with the explicit intention of involving spectator...

  11. Solar radiation and street temperature as function of street orientation. An analysis of the status quo and simulation of future scenarios towards sustainability in Bahrain

    Science.gov (United States)

    Silva, Joao Pinelo

    2017-11-01

    This paper discusses the contribution of street orientation towards the development of a comfortable microclimate for pedestrians in Bahrain. Increasing walkability is a global agenda to address issues such as a) transportation, b) energy consumption, c) health, and d) air pollution, all of which are topics of the sustainability agenda. Thermal comfort is one of the pre-requisites for walkability. In warm climates, this is a challenging goal. Street design is paramount for pedestrian comfort in warm climates. The roles of street orientation and aspect ratio are of particular importance as they determine the intake of solar radiation into the urban canyon. We investigate the state of affairs in Bahrain, by measuring the frequency with which the street orientations E-W, N-S, NE-SW, and NW-SE, currently occur. Research suggests that the street orientation E-W presents the lesser performance for mitigating the effects of heat gain. The ideal grid orientation would, therefore, be N-S, and NE-SW - NW-SE, avoiding street segments with E-W orientation. A countrywide analysis shows that E-W orientation accounts for the highest overall street length with 37%. The second most frequent orientation is N-S (29%), the best performer. NW-SE and NE-SW both have frequencies of only 17%. Preference for a street grid with N-S, NW-SE, and NE-SW orientation would improve the thermal performance of streets and provide a continuous network of a comfortable pedestrian environment. We simulate two future scenarios based on avoiding new E-W streets, or not. We measure their potential reduction in thermal gain and conclude that a simple policy could reduce solar exposition in 40%.

  12. Parametric laws to model urban pollutant dispersion with a street network approach

    Science.gov (United States)

    Soulhac, L.; Salizzoni, P.; Mejean, P.; Perkins, R. J.

    2013-03-01

    This study discusses the reliability of the street network approach for pollutant dispersion modelling in urban areas. This is essentially based on a box model, with parametric relations that explicitly model the main phenomena that contribute to the street canyon ventilation: the mass exchanges between the street and the atmosphere, the pollutant advection along the street axes and the pollutant transfer at street intersections. In the first part of the paper the focus is on the development of a model for the bulk transfer street/atmosphere, which represents the main ventilation mechanisms for wind direction that are almost perpendicular to the axis of the street. We then discuss the role of the advective transfer along the street axis on its ventilation, depending on the length of the street and the direction of the external wind. Finally we evaluate the performances of a box model integrating parametric exchange laws for these transfer phenomena. To that purpose we compare the prediction of the model to wind tunnel experiments of pollutant dispersion within a street canyon placed in an idealised urban district.

  13. NMR characterization of weak interactions between RhoGDI2 and fragment screening hits.

    Science.gov (United States)

    Liu, Jiuyang; Gao, Jia; Li, Fudong; Ma, Rongsheng; Wei, Qingtao; Wang, Aidong; Wu, Jihui; Ruan, Ke

    2017-01-01

    The delineation of intrinsically weak interactions between novel targets and fragment screening hits has long limited the pace of hit-to-lead evolution. Rho guanine-nucleotide dissociation inhibitor 2 (RhoGDI2) is a novel target that lacks any chemical probes for the treatment of tumor metastasis. Protein-observed and ligand-observed NMR spectroscopy was used to characterize the weak interactions between RhoGDI2 and fragment screening hits. We identified three hits of RhoGDI2 using streamlined NMR fragment-based screening. The binding site residues were assigned using non-uniformly sampled C α - and H α -based three dimensional NMR spectra. The molecular docking to the proposed geranylgeranyl binding pocket of RhoGDI2 was guided by NMR restraints of chemical shift perturbations and ligand-observed transferred paramagnetic relaxation enhancement. We further validated the weak RhoGDI2-hit interactions using mutagenesis and structure-affinity analysis. Weak interactions between RhoGDI2 and fragment screening hits were delineated using an integrated NMR approach. Binders to RhoGDI2 as a potential anti-cancer target have been first reported, and their weak interactions were depicted using NMR spectroscopy. Our work highlights the powerfulness and the versatility of the integrative NMR techniques to provide valuable structural insight into the intrinsically weak interactions between RhoGDI2 and the fragment screening hits, which could hardly be conceived using other biochemical techniques. Copyright © 2016 Elsevier B.V. All rights reserved.

  14. Development and psychometric evaluation of the Impact of Health Information Technology (I-HIT) scale.

    Science.gov (United States)

    Dykes, Patricia C; Hurley, Ann; Cashen, Margaret; Bakken, Suzanne; Duffy, Mary E

    2007-01-01

    The use of health information technology (HIT) for the support of communication processes and data and information access in acute care settings is a relatively new phenomenon. A means of evaluating the impact of HIT in hospital settings is needed. The purpose of this research was to design and psychometrically evaluate the Impact of Health Information Technology scale (I-HIT). I-HIT was designed to measure the perception of nurses regarding the ways in which HIT influences interdisciplinary communication and workflow patterns and nurses' satisfaction with HIT applications and tools. Content for a 43-item tool was derived from the literature, and supported theoretically by the Coiera model and by nurse informaticists. Internal consistency reliability analysis using Cronbach's alpha was conducted on the 43-item scale to initiate the item reduction process. Items with an item total correlation of less than 0.35 were removed, leaving a total of 29 items. Item analysis, exploratory principal component analysis and internal consistency reliability using Cronbach's alpha were used to confirm the 29-item scale. Principal components analysis with Varimax rotation produced a four-factor solution that explained 58.5% of total variance (general advantages, information tools to support information needs, information tools to support communication needs, and workflow implications). Internal consistency of the total scale was 0.95 and ranged from 0.80-0.89 for four subscales. I-HIT demonstrated psychometric adequacy and is recommended to measure the impact of HIT on nursing practice in acute care settings.

  15. Reproductive health behaviour of street youth and associated ...

    African Journals Online (AJOL)

    McRoy

    2014-03-30

    Mar 30, 2014 ... street, alcohol drinking, cigarette smoking and khat chewing. Among the .... Street youth: In this study, youth is defined as the people ... factors that influence sexual behaviours of ... means of preventing pregnancy. Condom ...

  16. [Effect of greenbelt on pollutant dispersion in street canyon].

    Science.gov (United States)

    Xu, Wei-Jia; Xing, Hong; Yu, Zhi

    2012-02-01

    The effect feature of greenbelt on flow field and pollutant dispersion in urban street canyon was researched. The greenbelt was assumed as uniform porous media and its aerodynamics property defined by the pressure loss coefficient. Subsequently, the pollutant dispersion in the street canyon of which there was greenbelt in the middle was simulated with the steady-state standard kappa-epsilon turbulence model and species transport equation. The simulated results agreed well with the wind-tunnel data. Compared with the treeless case, it finds that the street canyon contain a clockwise vortex, the pollutant concentration of the leeward was several times than the windward and the growth rate of pollutant concentration was 46.0%. The further simulation for the impact of tree crown position on the airflow and pollutant dispersion finds that the height of major vortex center in the street canyon increases with the height of tree crown and gradually closes the top of windward building This causes that the average wind speed in the street canyon decreases. Especially when the top of tree crown over the roof and hinder the air flow above the street canyon, the average pollutant concentration increases with the height of tree crown rapidly.

  17. Plasma exchange to remove HIT antibodies: dissociation between enzyme-immunoassay and platelet activation test reactivities.

    Science.gov (United States)

    Warkentin, Theodore E; Sheppard, Jo-Ann I; Chu, F Victor; Kapoor, Anil; Crowther, Mark A; Gangji, Azim

    2015-01-01

    Repeated therapeutic plasma exchange (TPE) has been advocated to remove heparin-induced thrombocytopenia (HIT) IgG antibodies before cardiac/vascular surgery in patients who have serologically-confirmed acute or subacute HIT; for this situation, a negative platelet activation assay (eg, platelet serotonin-release assay [SRA]) has been recommended as the target serological end point to permit safe surgery. We compared reactivities in the SRA and an anti-PF4/heparin IgG-specific enzyme immunoassay (EIA), testing serial serum samples in a patient with recent (subacute) HIT who underwent serial TPE precardiac surgery, as well as for 15 other serially-diluted HIT sera. We observed that post-TPE/diluted HIT sera-when first testing SRA-negative-continue to test strongly positive by EIA-IgG. This dissociation between the platelet activation assay and a PF4-dependent immunoassay for HIT antibodies indicates that patients with subacute HIT undergoing repeated TPE before heparin reexposure should be tested by serial platelet activation assays even when their EIAs remain strongly positive. © 2015 by The American Society of Hematology.

  18. Progress on FIR interferometry and Thomson Scattering measurements on HIT-SI3

    Science.gov (United States)

    Everson, Christopher; Jarboe, Thomas; Morgan, Kyle

    2017-10-01

    Spatially resolved measurements of the electron temperature (Te) and density (ne) will be fundamental in assessing the degree to which HIT-SI3 demonstrates closed magnetic flux and energy confinement. Further, electron temperature measurements have not yet been made on an inductively-driven spheromak. Far infrared (FIR) interferometer and Thomson Scattering (TS) systems have been installed on the HIT-SI3 spheromak. The TS system currently implemented on HIT-SI3 was originally designed for other magnetic confinement experiments, and progress continues toward modifying and optimizing for HIT-SI3 plasmas. Initial results suggest that the electron temperature is of order 10 eV. Plans to modify the TS system to provide more sensitivity and accuracy at low temperatures are presented. The line-integrated ne is measured on one chord by the FIR interferometer, with densities near 5x1019 m-3. Four cylindrical volumes have been added to the HIT-SI3 apparatus to enhance passive pumping. It is hoped that this will allow for more control of the density during the 2 ms discharges. Density measurements from before and after the installation of the passive pumping volumes are presented for comparison.

  19. 76 FR 4352 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee's...

    Science.gov (United States)

    2011-01-25

    ... Technology; HIT Policy Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National... only. Name of Committees: HIT Policy Committee's Workgroups: Meaningful Use, Privacy & Security Tiger..., implementation specifications, and certification criteria are needed. Date and Time: The HIT Policy Committee...

  20. Notes on LED Installations in Street Illumination

    Directory of Open Access Journals (Sweden)

    Elisabeta Spunei

    2014-09-01

    Full Text Available The paper presents a study made on choosing LED street lighting installations, such that the quality requirements for exterior artificial lighting are fulfilled. We analyze two types of LED street lighting installations from a technical point of view, together with lighting level and brightness values obtained during the measurements. Following on the field measurements, the lighting quality parameters are calculated, and, for the lighting installation with the best performance, optimal mounting suggestions are made. The optimal quality parameters are calculated by simulations using the Dialux software. The same software and the same light sources we also compute an optimal street lighting by determining the size of the installation that provides the best lighting parameter values.

  1. The T10 beam produces a few hits per event. In ALICE the SSD will have to cope with many hits per strip. In the three centimeters of aluminium the beam will produce many secondary particles. This increases the chance of multiple hits per strip, although not to the level in ALICE.

    CERN Multimedia

    Nooren, G.

    2004-01-01

    The T10 beam produces a few hits per event. In ALICE the SSD will have to cope with many hits per strip. In the three centimeters of aluminium the beam will produce many secondary particles. This increases the chance of multiple hits per strip, although not to the level in ALICE.

  2. Childcare needs of female street vendors in Mexico City.

    Science.gov (United States)

    Hernandez, P; Zetina, A; Tapia, M; Ortiz, C; Soto, I C

    1996-06-01

    This article reports on strategies developed by female street vendors (vendedoras ambulantes) in Mexico City to ensure the care of their young children in the absence of a specific and operational government policy to fulfil this need. The information concerning child care and health was gathered by a survey of 426 street traders selected by multi-stage random cluster sampling in four of the administrative districts (delegaciones politicas) of Mexico City during 1990. It was found that, as mothers of young children, street vendors most frequently looked after their children personally on the street or left them with other members of the family. Related factors were availability of alternative child care providers in the family, the age of the children and working conditions of the mother. Children who remained on the streets with their mothers suffered more frequently from gastro-intestinal diseases and accidents than the national average. The incidence of acute respiratory diseases, however, was similar in the cases of maternal care in the street and care by family members in another environment. Existing public health measures show a greater concern for the health of food consumers than that of workers in this area. Current public policy seeks to regulate street vending activities and to concentrate traders in ad hoc areas and facilities. Our research results document the need for actions that can contribute to an improvement in the care and health conditions of these young children.

  3. Platelet count recovery and seroreversion in immune HIT despite continuation of heparin: further observations and literature review.

    Science.gov (United States)

    Shih, Andrew W; Sheppard, Jo-Ann I; Warkentin, Theodore E

    2017-10-05

    One of the standard distinctions between type 1 (non-immune) and type 2 (immune-mediated) heparin-induced thrombocytopenia (HIT) is the transience of thrombocytopenia: type 1 HIT is viewed as early-onset and transient thrombocytopenia, with platelet count recovery despite continuing heparin administration. In contrast, type 2 HIT is viewed as later-onset (i. e., 5 days or later) thrombocytopenia in which it is generally believed that platelet count recovery will not occur unless heparin is discontinued. However, older reports of type 2 HIT sometimes did include the unexpected observation that platelet counts could recover despite continued heparin administration, although without information provided regarding changes in HIT antibody levels in association with platelet count recovery. In recent years, some reports of type 2 HIT have confirmed the observation that platelet count recovery can occur despite continuing heparin administration, with serological evidence of waning levels of HIT antibodies ("seroreversion"). We now report two additional patient cases of type 2 HIT with platelet count recovery despite ongoing therapeutic-dose (1 case) or prophylactic-dose (1 case) heparin administration, in which we demonstrate concomitant waning of HIT antibody levels. We further review the literature describing this phenomenon of HIT antibody seroreversion and platelet count recovery despite continuing heparin administration. Our observations add to the concept that HIT represents a remarkably transient immune response, including sometimes even when heparin is continued.

  4. Health Information Technologies-Academic and Commercial Evaluation (HIT-ACE) methodology: description and application to clinical feedback systems.

    Science.gov (United States)

    Lyon, Aaron R; Lewis, Cara C; Melvin, Abigail; Boyd, Meredith; Nicodimos, Semret; Liu, Freda F; Jungbluth, Nathaniel

    2016-09-22

    Health information technologies (HIT) have become nearly ubiquitous in the contemporary healthcare landscape, but information about HIT development, functionality, and implementation readiness is frequently siloed. Theory-driven methods of compiling, evaluating, and integrating information from the academic and commercial sectors are necessary to guide stakeholder decision-making surrounding HIT adoption and to develop pragmatic HIT research agendas. This article presents the Health Information Technologies-Academic and Commercial Evaluation (HIT-ACE) methodology, a structured, theory-driven method for compiling and evaluating information from multiple sectors. As an example demonstration of the methodology, we apply HIT-ACE to mental and behavioral health measurement feedback systems (MFS). MFS are a specific class of HIT that support the implementation of routine outcome monitoring, an evidence-based practice. HIT-ACE is guided by theories and frameworks related to user-centered design and implementation science. The methodology involves four phases: (1) coding academic and commercial materials, (2) developer/purveyor interviews, (3) linking putative implementation mechanisms to hit capabilities, and (4) experimental testing of capabilities and mechanisms. In the current demonstration, phase 1 included a systematic process to identify MFS in mental and behavioral health using academic literature and commercial websites. Using user-centered design, implementation science, and feedback frameworks, the HIT-ACE coding system was developed, piloted, and used to review each identified system for the presence of 38 capabilities and 18 additional characteristics via a consensus coding process. Bibliometic data were also collected to examine the representation of the systems in the scientific literature. As an example, results are presented for the application of HIT-ACE phase 1 to MFS wherein 49 separate MFS were identified, reflecting a diverse array of characteristics

  5. An Art of Resistance: From the Street to the Classroom

    Science.gov (United States)

    Chung, Sheng Kuan

    2009-01-01

    Rooted in graffiti culture and its attitude toward the world, street art is regarded as a postgraffiti movement. Street art encompasses a wide array of media and techniques, such as traditional spray-painted tags, stickers, stencils, posters, photocopies, murals, paper cutouts, mosaics, street installations, performances, and video projections…

  6. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Hematology, Oncology and Transfusion Medicine Center, Vilnius University Hospital Santariskiu Klinikos, Vilnius LT-08661, Lithuania; Department of Human and Medical Genetics, Vilnius University, Vilnius LT-08661, Lithuania; Department of Internal, Family Medicine and Oncology, Vilnius University, Vilnius LT-08661, ...

  7. 75 FR 3906 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee's...

    Science.gov (United States)

    2010-01-25

    ... Technology; HIT Policy Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National... only. Name of Committees: HIT Policy Committee's Workgroups: Meaningful Use, Privacy & Security Policy... specifications, and certification criteria are needed. Date and Time: The HIT Policy Committee Workgroups will...

  8. Numerical simulation on pollutant dispersion from vehicle exhaust in street configurations.

    Science.gov (United States)

    Yassin, Mohamed F; Kellnerová, R; Janour, Z

    2009-09-01

    The impact of the street configurations on pollutants dispersion from vehicles exhausts within urban canyons was numerically investigated using a computational fluid dynamics (CFD) model. Three-dimensional flow and dispersion of gaseous pollutants were modeled using standard kappa - epsilon turbulence model, which was numerically solved based on Reynolds-averaged Navier-Stokes equations by the commercial CFD code FLUENT. The concentration fields in the urban canyons were examined in three cases of street configurations: (1) a regular-shaped intersection, (2) a T-shaped intersection and (3) a Skew-shaped crossing intersection. Vehicle emissions were simulated as double line sources along the street. The numerical model was validated against wind tunnel results in order to optimize the turbulence model. Numerical predictions agreed reasonably well with wind tunnel results. The results obtained indicate that the mean horizontal velocity was very small in the center near the lower region of street canyon. The lowest turbulent kinetic energy was found at the separation and reattachment points associated with the corner of the down part of the upwind and downwind buildings in the street canyon. The pollutant concentration at the upwind side in the regular-shaped street intersection was higher than that in the T-shaped and Skew-shaped street intersections. Moreover, the results reveal that the street intersections are important factors to predict the flow patterns and pollutant dispersion in street canyon.

  9. Street Connectivity is Negatively Associated with Physical Activity in Canadian Youth

    Directory of Open Access Journals (Sweden)

    Ian Janssen

    2011-08-01

    Full Text Available Street connectivity, defined as how well streets connect to one and other and the density of intersections, is positively associated with active transportation in adults. Our objective was to study the relation between street connectivity and physical activity in youth. Study participants consisted of 8,535 students in grades 6–10 from 180 schools across Canada who completed the 2006 Health Behaviour in School-aged Children (HBSC survey. Street connectivity was measured in a 5 km circular buffer around these schools using established geographic information system measures. Physical activity performed outside of school hours was assessed by questionnaire, and multi-level regression analyses were used to estimate associations with street connectivity after controlling for several covariates. Compared to students living in the highest street connectivity quartile, those in the second (relative risk = 1.22, 95% confidence interval = 1.10–1.35, third (1.25, 1.13–1.37, and fourth (1.21, 1.09–1.34 quartiles were more likely to be physically active outside of school. In conclusion, youth in neighbourhoods with the most highly connected streets reported less physical activity outside of school than youth from neighbourhoods with less connected streets. Relationships between street connectivity and physical activity reported in this national study are in the opposite direction to those previously observed for active transportation in adult populations.

  10. Analyzing Street Art to Present the Heritage of George Town, Malaysia

    Directory of Open Access Journals (Sweden)

    Seyedehelham Sadatiseyedmahalleh

    2015-08-01

    Full Text Available Street art comprises all kinds of art developed in public locations. This form of art has spread to all heritage streets in George Town, the capital of Penang Island, which is also a known UNESCO World Heritage Site. However, instead of its heritage, food, and interesting past life and structure, the rapid multiplication of street art in George Town has created a new and unusual art that attracts tourists. Street art has spread to small roads and heritage streets in the city. This art increases the awareness of spectators by introducing them to the rich history of these streets and inducing a lively concept in the inner city of George Town. Accordingly, the impact of iron rod sculptures and murals, which comprises approximately 90% of street art in George Town, were determined to explore and identify the effects of this street art on this world heritage site. The findings were obtained from 263 out of 306 questionnaires accomplished by tourists in George Town. The results confirm that tourists prefer murals over iron rod sculptures. Iron rod sculptures are designed to tell the history of the street, whereas murals are designed to create aesthetic value. The findings indicated that similar to iron rod sculptures, more control should be exercised on the subjects of murals.

  11. The City Street

    NARCIS (Netherlands)

    H.C. van der Wouden

    1999-01-01

    Original title: De stad op straat. The city street; the public space in perspective (De stad op straat; de openbare ruimte in perspectief) by the Netherlands Institute for Social Research/SCP is intended to contribute to the formation of new ideas about the public space and the future of

  12. Drug use among street children and adolescents: what helps?

    Directory of Open Access Journals (Sweden)

    Yone Gonçalves de Moura

    Full Text Available The aim of this study was to investigate factors associated to frequent and heavy drug use among street children and adolescents aged 10 to 18 years. A sample of 2,807 street children and adolescents from the 27 Brazilian state capital cities was analyzed. A World Health Organization questionnaire for non-students was adapted for use in Brazil. Data analysis was performed using logistic regression and decision tree models. Factors inversely associated with frequent and heavy drug use were: being age nine to 11 years (OR = 0.1; school attendance (OR = 0.3; daily time (one to five hours spent on the streets (OR = 0.3 and 0.4; not sleeping on the streets (OR = 0.4; being on the streets for less than one year (OR = 0.4; maintenance of some family bonds (OR = 0.5; presence on the streets of a family member (OR = 0.6; not suffering domestic violence (OR = 0.6; being female (OR = 0.8. All of these variables were significant at the p < 0.05 level. The findings suggest that being younger, having family bonds and engagement in school are important protective factors that affect drug use among this population and should be considered in the formulation of public policies.

  13. Identification on the street: A field comparison of police street identifications and video line-ups in England

    OpenAIRE

    Davis, Josh P.; Valentine, Tim; Memon, Amina; Roberts, Andrew J.

    2015-01-01

    A street identification or live show-up provides an eyewitness with an opportunity to identify a suspect shortly after a crime. In England, the majority of suspects identified are subsequently included in a video line-up for the same witness to view. In Study 1, robbery squad data from three English police forces recorded 696 crimes, the identification procedures employed and prosecution decisions. A street identification was the most frequent identification procedure, being attempted in 22.7...

  14. The Code of the Street and Violent Versus Property Crime Victimization.

    Science.gov (United States)

    McNeeley, Susan; Wilcox, Pamela

    2015-01-01

    Previous research has shown that individuals who adopt values in line with the code of the street are more likely to experience violent victimization (e.g., Stewart, Schreck, & Simons, 2006). This study extends this literature by examining the relationship between the street code and multiple types of violent and property victimization. This research investigates the relationship between street code-related values and 4 types of victimization (assault, breaking and entering, theft, and vandalism) using Poisson-based multilevel regression models. Belief in the street code was associated with higher risk of experiencing assault, breaking and entering, and vandalism, whereas theft victimization was not related to the street code. The results suggest that the code of the street influences victimization broadly--beyond violence--by increasing behavior that provokes retaliation from others in various forms.

  15. Street children in Mafikeng, North-West Province: A qualitative study ...

    African Journals Online (AJOL)

    The general perception, on the part of South African society, is that street children are a major social menace. Yet the reality is that, street children are a vulnerable group that suffer both psychological and physical violence including sexual abuse. This qualitative study investigated the social experiences of street children in ...

  16. Socio-economic and hygiene features of street food vending in ...

    African Journals Online (AJOL)

    The objectives of the study were firstly to determine the health risks associated with street food vending, secondly to determine the opinions of street food ... such as South Africa be allowed to earn their livelihood by means of an 'easy-to-enter' business such as street food vending when hygiene standards are acceptable.

  17. 75 FR 65636 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee...

    Science.gov (United States)

    2010-10-26

    ... Technology; HIT Standards Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Standards... Strategic Plan, and in accordance with policies developed by the HIT Policy Committee. Date and Time: The...

  18. 75 FR 57027 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee...

    Science.gov (United States)

    2010-09-17

    ... Technology; HIT Standards Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Standards... Strategic Plan, and in accordance with policies developed by the HIT Policy Committee. Date and Time: The...

  19. 75 FR 42090 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee...

    Science.gov (United States)

    2010-07-20

    ... Technology; HIT Standards Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Standards... Strategic Plan, and in accordance with policies developed by the HIT Policy Committee. Date and Time: The...

  20. Laboratory tests for identification or exclusion of heparin induced thrombocytopenia: HIT or miss?

    Science.gov (United States)

    Favaloro, Emmanuel J

    2018-02-01

    Heparin induced thrombocytopenia (HIT) is a potentially fatal condition that arises subsequent to formation of antibodies against complexes containing heparin, usually platelet-factor 4-heparin ("anti-PF4-heparin"). Assessment for HIT involves both clinical evaluation and, if indicated, laboratory testing for confirmation or exclusion, typically using an initial immunological assay ("screening"), and only if positive, a secondary functional assay for confirmation. Many different immunological and functional assays have been developed. The most common contemporary immunological assays comprise enzyme-linked immunosorbent assay [ELISA], chemiluminescence, lateral flow, and particle gel techniques. The most common functional assays measure platelet aggregation or platelet activation events (e.g., serotonin release assay; heparin-induced platelet activation (HIPA); flow cytometry). All assays have some sensitivity and specificity to HIT antibodies, but differ in terms of relative sensitivity and specificity for pathological HIT, as well as false negative and false positive error rate. This brief article overviews the different available laboratory methods, as well as providing a suggested approach to diagnosis or exclusion of HIT. © 2017 Wiley Periodicals, Inc.

  1. Lead in Glasgow street dirt and soil

    Energy Technology Data Exchange (ETDEWEB)

    Farmer, J G [Univ. of Glasgow; Lyon, T D.B.

    1977-07-01

    The levels of lead in city street dirt and in soil from various locations in Glasgow were investigated during spring 1976. Lead concentrations in street dirt ranged from 150 to 2300 ppM, mean 960 ppM, and were significantly elevated with respect to the observed ''natural'' level of 78 ppM. Lead derived from anti-knock compounds in petrol and introduced to the environment via automobile exhausts was clearly implicated as the main source of lead pollution in a series of soil lead measurements at the centre and periphery of eight Glasgow parks. Various chemical leaching techniques were employed and compared. Less than 5 percent of street dirt and soil lead was found to be associated with the organic phase.

  2. Street-Level Bureaucrats as Individual Policymakers:

    DEFF Research Database (Denmark)

    Baviskar, Siddhartha; Winter, Søren

    2016-01-01

    Lipsky (1980) pointed out that street-level bureaucrats (SLBs) are important policymakers due to the discretion they exercise and argued from a structural perspective that these workers manifest relatively similar coping behaviors owing to their shared working conditions, characterized by chronic......Lipsky (1980) pointed out that street-level bureaucrats (SLBs) are important policymakers due to the discretion they exercise and argued from a structural perspective that these workers manifest relatively similar coping behaviors owing to their shared working conditions, characterized...

  3. MIDAS and HIT-6 French translation: reliability and correlation between tests.

    Science.gov (United States)

    Magnoux, E; Freeman, M A; Zlotnik, G

    2008-01-01

    The aim was to evaluate the test-retest reliability of the French translation of the Migraine Disability Assessment (MIDAS) and Headache Impact Test (HIT)-6 questionnaires as applied to episodic and chronic headaches and to assess the correlation between these two questionnaires. The MIDAS and HIT-6 questionnaires, which assess the degree of migraine-related functional disability, are widely used in headache treatment clinics. The French translation has not been checked for test-retest reliability. MIDAS involves recall, over the previous 3 months, of the number of days with functional disability with regard to work and to home and social life. HIT-6 involves a more subjective and general assessment of headache-related disability over the previous 4 weeks. We expect that there may be greater impact recall bias for chronic headaches than for episodic headaches and considered it important to be able to determine if the reliability of these questionnaires is equally good for these two patient populations. Given that both questionnaires have the same objective, that of assessing headache impact, it was thought useful to determine if their results might show a correlation and if they could thus be used interchangeably. The study was approved by an external ethics committee. The subjects were patients who regularly visit the Clinique de la Migraine de Montréal, which specializes in the treatment of headaches. The MIDAS and HIT-6 questionnaires were completed by the patients during their regular visit. Twelve days later, the same questionnaires were mailed with a prepaid return envelope. Sixty-five patients were required in both the episodic and chronic headache groups, assuming an 80% questionnaire return rate. One hundred and eighty-five patients were enrolled, and 143 completed the study, 75 with episodic headaches and 68 with chronic headaches. The questionnaire return rate was 78.9%. On average, questionnaires were completed a second time 21 days after the first

  4. CODASC : a database for the validation of street canyon dispersion models

    OpenAIRE

    Gromke, C.B.

    2013-01-01

    CODASC stands for Concentration Data of Street Canyons (CODASC 2008, www.codasc.de). It is a database which provides traffic pollutant concentrations in urban street canyons obtained from wind-tunnel dispersion experiments. CODASC comprises concentration data of street canyons with different aspect ratios subjected to various wind directions and also for street canyons with tree-avenues. The database includes concentration data of tree-avenue configurations of different tree arrangement, tree...

  5. HIT or miss? A comprehensive contemporary investigation of laboratory tests for heparin induced thrombocytopenia.

    Science.gov (United States)

    Favaloro, Emmanuel J; McCaughan, Georgia; Mohammed, Soma; Lau, Kun Kan Edwin; Gemmell, Rosalie; Cavanaugh, Lauren; Donikian, Dea; Kondo, Mayuko; Brighton, Timothy; Pasalic, Leonardo

    2018-04-17

    Heparin induced thrombocytopenia (HIT) is a rare but potentially fatal complication of heparin therapy, which in a proportion of patients causes platelet activation and thrombosis. Initial clinical assessment of the likelihood of HIT is facilitated by laboratory testing to confirm or exclude HIT. This prospective investigation was performed over an 18-month period, and has involved testing of over 300 test samples from over 100 consecutive patients. Clinical assessment by 4T score was supplemented by laboratory tests that comprised both immunological [lateral flow ('STiC'), chemiluminescence (AcuStar; HIT-IgG (PF4-H) ), ELISA (Asserachrom HPIA IgG)] and functional assays [SRA, platelet aggregation using whole blood ('Multiplate') and platelet rich plasma ('LTA')]. We observed both false positive and false negative test findings with most assays. Overall, the whole blood aggregation method provided a reasonable alternative to SRA for identifying functional HIT. STiC, AcuStar and ELISA procedures were fairly comparable in terms of screening for HIT, although STiC and AcuStar both yielded false negatives, albeit also resulting in fewer false positives than ELISA. The 4T score had less utility in our patient cohort than we were expecting, although there was an association with the likelihood of HIT. Nevertheless, we accept that our observations are based on limited test numbers. In conclusion, no single approach (clinical or laboratory) was associated with optimal sensitivity or specificity of HIT exclusion or identification, and thus, a combination of clinical evaluation and laboratory testing will best ensure the accuracy of diagnosis. Crown Copyright © 2018. Published by Elsevier B.V. All rights reserved.

  6. Playing With the City: Street Art and Videogames

    DEFF Research Database (Denmark)

    Vazques Marquez, Israel; Pajares Tosca, Susana

    2017-01-01

    In this paper we introduce and describe the phenomenon of videogame street art as a specific kind of street art. We consider its materiality and significance, and conceptualize it in the light of a double manifestation of play: the playful appropriation of the city by the artist and the fact...... that street art encapsulates the act of playing videogames in a visual form. Digital play spills out of our computer screens and occupies the urban space with the explicit intention of involving spectators, who are invited to play in symbolic ways that actualize nostalgic memories of gaming and can be related...

  7. A qualitative enquiry into OpenStreetMap making

    Science.gov (United States)

    Lin, Yu-Wei

    2011-04-01

    Based on a case study on the OpenStreetMap community, this paper provides a contextual and embodied understanding of the user-led, user-participatory and user-generated produsage phenomenon. It employs Grounded Theory, Social Worlds Theory, and qualitative methods to illuminate and explores the produsage processes of OpenStreetMap making, and how knowledge artefacts such as maps can be collectively and collaboratively produced by a community of people, who are situated in different places around the world but engaged with the same repertoire of mapping practices. The empirical data illustrate that OpenStreetMap itself acts as a boundary object that enables actors from different social worlds to co-produce the Map through interacting with each other and negotiating the meanings of mapping, the mapping data and the Map itself. The discourses also show that unlike traditional maps that black-box cartographic knowledge and offer a single dominant perspective of cities or places, OpenStreetMap is an embodied epistemic object that embraces different world views. The paper also explores how contributors build their identities as an OpenStreetMaper alongside some other identities they have. Understanding the identity-building process helps to understand mapping as an embodied activity with emotional, cognitive and social repertoires.

  8. Validation of the Impact of Health Information Technology (I-HIT) Scale: an international collaborative.

    Science.gov (United States)

    Dykes, Patricia C; Hurley, Ann C; Brown, Suzanne; Carr, Robyn; Cashen, Margaret; Collins, Rita; Cook, Robyn; Currie, Leanne; Docherty, Charles; Ensio, Anneli; Foster, Joanne; Hardiker, Nicholas R; Honey, Michelle L L; Killalea, Rosaleen; Murphy, Judy; Saranto, Kaija; Sensmeier, Joyce; Weaver, Charlotte

    2009-01-01

    In 2005, the Healthcare Information Management Systems Society (HIMSS) Nursing Informatics Community developed a survey to measure the impact of health information technology (HIT), the I-HIT Scale, on the role of nurses and interdisciplinary communication in hospital settings. In 2007, nursing informatics colleagues from Australia, England, Finland, Ireland, New Zealand, Scotland and the United States formed a research collaborative to validate the I-HIT across countries. All teams have completed construct and face validation in their countries. Five out of six teams have initiated reliability testing by practicing nurses. This paper reports the international collaborative's validation of the I-HIT Scale completed to date.

  9. Street art a jeho vliv na současnou českou malbu

    OpenAIRE

    Grabmüllerová, Eva

    2009-01-01

    Street Art and Its Influence on Contemporary Czech Painting Street art as a concept refers to an artistic expression, which is, however, not defined by one homogenous technique or subject. The only attribute that conjoins the diverse forms and subjects of street art is a very specific urban area utilization. Although street art encompasses many diverse forms and techniques, the most prevalent ones are sticker art, street posters art, stencil graffiti, murals, traditional graffiti artwork, art...

  10. Social Sustainability of Shopping Streets in Ankara

    Directory of Open Access Journals (Sweden)

    Özge YALÇINER ERCOŞKUN

    2013-02-01

    Full Text Available Shopping streets are integral parts of public spaces in traditional shopping areas of Central Business Districts (CBD. Furthermore, as modern shopping venues, shopping centers offer advantages for modern lifestyles with spacious shopping areas, variety of commercial and social activities, and economic value of their investments. These advantages act in favor of shopping centers and improve the level of shopping street social sustainability and its relevant concepts. The aim of this study is to analyze the main shopping streets of Ankara, using the concepts of social sustainability. In this study, these concepts, such as locality, identity, vitality, viability, sense of place, conviviality, meaning and local characteristics of the shopping streets are investigated. For the first time, the retail unit locations in Ankara, their brands and their business types, are illustrated on thematic land use maps using Geographical Information Systems (GIS software. Next, population activities and consumer spatial behavior are observed and marked on maps that are also referred to as social sustainability maps. The results of the study can be useful in formulating strategies within the framework of social sustainability, which is a relatively new concept.

  11. Effective progression of nuclear magnetic resonance-detected fragment hits.

    Science.gov (United States)

    Eaton, Hugh L; Wyss, Daniel F

    2011-01-01

    Fragment-based drug discovery (FBDD) has become increasingly popular over the last decade as an alternate lead generation tool to HTS approaches. Several compounds have now progressed into the clinic which originated from a fragment-based approach, demonstrating the utility of this emerging field. While fragment hit identification has become much more routine and may involve different screening approaches, the efficient progression of fragment hits into quality lead series may still present a major bottleneck for the broadly successful application of FBDD. In our laboratory, we have extensive experience in fragment-based NMR screening (SbN) and the subsequent iterative progression of fragment hits using structure-assisted chemistry. To maximize impact, we have applied this approach strategically to early- and high-priority targets, and those struggling for leads. Its application has yielded a clinical candidate for BACE1 and lead series in about one third of the SbN/FBDD projects. In this chapter, we will give an overview of our strategy and focus our discussion on NMR-based FBDD approaches. Copyright © 2011 Elsevier Inc. All rights reserved.

  12. A street rubbish detection algorithm based on Sift and RCNN

    Science.gov (United States)

    Yu, XiPeng; Chen, Zhong; Zhang, Shuo; Zhang, Ting

    2018-02-01

    This paper presents a street rubbish detection algorithm based on image registration with Sift feature and RCNN. Firstly, obtain the rubbish region proposal on the real-time street image and set up the CNN convolution neural network trained by the rubbish samples set consists of rubbish and non-rubbish images; Secondly, for every clean street image, obtain the Sift feature and do image registration with the real-time street image to obtain the differential image, the differential image filters a lot of background information, obtain the rubbish region proposal rect where the rubbish may appear on the differential image by the selective search algorithm. Then, the CNN model is used to detect the image pixel data in each of the region proposal on the real-time street image. According to the output vector of the CNN, it is judged whether the rubbish is in the region proposal or not. If it is rubbish, the region proposal on the real-time street image is marked. This algorithm avoids the large number of false detection caused by the detection on the whole image because the CNN is used to identify the image only in the region proposal on the real-time street image that may appear rubbish. Different from the traditional object detection algorithm based on the region proposal, the region proposal is obtained on the differential image not whole real-time street image, and the number of the invalid region proposal is greatly reduced. The algorithm has the high mean average precision (mAP).

  13. HIT Solar Cells with N-Type Low-Cost Metallurgical Si

    Directory of Open Access Journals (Sweden)

    Xing Yang

    2018-01-01

    Full Text Available A conversion efficiency of 20.23% of heterojunction with intrinsic thin layer (HIT solar cell on 156 mm × 156 mm metallurgical Si wafer has been obtained. Applying AFORS-HET software simulation, HIT solar cell with metallurgical Si was investigated with regard to impurity concentration, compensation level, and their impacts on cell performance. It is known that a small amount of impurity in metallurgical Si materials is not harmful to solar cell properties.

  14. Neighborhood sampling: how many streets must an auditor walk?

    Science.gov (United States)

    McMillan, Tracy E; Cubbin, Catherine; Parmenter, Barbara; Medina, Ashley V; Lee, Rebecca E

    2010-03-12

    This study tested the representativeness of four street segment sampling protocols using the Pedestrian Environment Data Scan (PEDS) in eleven neighborhoods surrounding public housing developments in Houston, TX. The following four street segment sampling protocols were used (1) all segments, both residential and arterial, contained within the 400 meter radius buffer from the center point of the housing development (the core) were compared with all segments contained between the 400 meter radius buffer and the 800 meter radius buffer (the ring); all residential segments in the core were compared with (2) 75% (3) 50% and (4) 25% samples of randomly selected residential street segments in the core. Analyses were conducted on five key variables: sidewalk presence; ratings of attractiveness and safety for walking; connectivity; and number of traffic lanes. Some differences were found when comparing all street segments, both residential and arterial, in the core to the ring. Findings suggested that sampling 25% of residential street segments within the 400 m radius of a residence sufficiently represents the pedestrian built environment. Conclusions support more cost effective environmental data collection for physical activity research.

  15. Saving Mango Street

    Science.gov (United States)

    Van Winkle, Katie

    2012-01-01

    The author first learned about cultural diversity and racial justice in Mr. Sanderson's middle school English class. They read a book called "The House on Mango Street" by Sandra Cisneros and learned about a different culture, but also about a community with striking similarities to their own. The main character in the novel, Esperanza,…

  16. Restoring Detroit's Street Lighting System

    Energy Technology Data Exchange (ETDEWEB)

    Kinzey, Bruce [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-09-30

    The City of Detroit is in the midst of a comprehensive restoration of its street lighting system that includes transitioning the existing HPS sources to LED. This report provides an objective review of the circumstances surrounding the system restoration, the processes undertaken and decisions made, and the results so far — and contains useful information about issues that arise during large-scale LED street lighting projects.

  17. CODASC : a database for the validation of street canyon dispersion models

    NARCIS (Netherlands)

    Gromke, C.B.

    2013-01-01

    CODASC stands for Concentration Data of Street Canyons (CODASC 2008, www.codasc.de). It is a database which provides traffic pollutant concentrations in urban street canyons obtained from wind-tunnel dispersion experiments. CODASC comprises concentration data of street canyons with different aspect

  18. Biophysics: for HTS hit validation, chemical lead optimization, and beyond.

    Science.gov (United States)

    Genick, Christine C; Wright, S Kirk

    2017-09-01

    There are many challenges to the drug discovery process, including the complexity of the target, its interactions, and how these factors play a role in causing the disease. Traditionally, biophysics has been used for hit validation and chemical lead optimization. With its increased throughput and sensitivity, biophysics is now being applied earlier in this process to empower target characterization and hit finding. Areas covered: In this article, the authors provide an overview of how biophysics can be utilized to assess the quality of the reagents used in screening assays, to validate potential tool compounds, to test the integrity of screening assays, and to create follow-up strategies for compound characterization. They also briefly discuss the utilization of different biophysical methods in hit validation to help avoid the resource consuming pitfalls caused by the lack of hit overlap between biophysical methods. Expert opinion: The use of biophysics early on in the drug discovery process has proven crucial to identifying and characterizing targets of complex nature. It also has enabled the identification and classification of small molecules which interact in an allosteric or covalent manner with the target. By applying biophysics in this manner and at the early stages of this process, the chances of finding chemical leads with novel mechanisms of action are increased. In the future, focused screens with biophysics as a primary readout will become increasingly common.

  19. The lived experiences of children living on the streets of Hillbrow

    Directory of Open Access Journals (Sweden)

    Chris Myburgh

    2015-05-01

    Full Text Available Background: The effects of daily abuse and hardship on the streets lead to poor mental health in children living on the streets, resulting in them choosing ineffective and self-destructive coping strategies that impact their physical health and overall sense of wellbeing. The facilitation of the mental health of children living on the streets who are subjected to daily threats to their survival is thus crucial. Objectives: The aim of this research was to explore and describe the lived experiences of children living on the streets of Hillbrow, Johannesburg. Method: The research design was qualitative, exploratory, descriptive and contextual. A purposive sample was selected through a temporary shelter in Johannesburg, Gauteng, South Africa and consisted of 14 male children living on the streets. Data were collected using drawings, in-depth phenomenological interviews and field notes. The central interview opening statement was: ‘Tell me about your life on the street’. Results: The results obtained indicated that children living on the streets are threatened, exploited and exposed to physical, sexual and emotional abuse on a daily basis by the community, the authorities and other street dwellers. This leads to feelings of sadness, fear, anxiety, misery, despair, hopelessness, helplessness and suicide ideation, which in turn lead to drug abuse and criminal activities. In contrast, positive feelings of sympathy for other children living on the streets emerged and these children also displayed perseverance, resilience and a striving for autonomy. Conclusion: Street life exposes children to a variety of experiences, both positive and negative. A striving after autonomy is clearly depicted by these children, who are able to tap into a range of responses, both on- and off-street.

  20. Density and diversity of OpenStreetMap road networks in China

    Directory of Open Access Journals (Sweden)

    Yingjia Zhang

    2015-12-01

    Full Text Available OpenStreetMap is a geographic information platform designed to provide real-time updates and user-generated content related to its freely available global map, and it is one of the most widely used examples of volunteered geographic information, a technique associated with so-called neogeography. This paper, based on the data from China’s OpenStreetMap road network in May 2014, taking 340 prefecture-level cities in China as its study area, presents the geometric-related (road density and attribute-related (type diversity spatial patterns of the OpenStreetMap road network, and explores their relationship. The results are as follows. (1 The distribution of OpenStreetMap road density in Shenzhen, Shanghai, Hong Kong, and Macao predominantly obeys a “positive skewness distribution”. OpenStreetMap data for eastern China shows a higher overall and circular structure. In central China, there are noticeable discrepancies in the road density, whereas in western China, the road density is low. (2 The OpenStreetMap road diversity shows a normal distribution. The spatial pattern for the so-called “Hu Huanyong line” was broken by the effect of diplomatic and strategic factors, showing a high diversity along the peripheral border, coastal cities, and core inland cites. (3 China’s OpenStreetMap is partitioned into four parts according to road density and diversity: high density and high diversity; low density and low diversity; high density and low diversity; and low density high diversity. (4 The OpenStreetMap geographical information-collection process and mechanism were analyzed, demonstrating that the road density reflects the preponderance of traffic in the real world. OpenStreetMap road diversity reflects the road-related geographic information demand and value, and it also reflects the interests of users toward to OpenStreetMap geographical information.

  1. High-Throughput Screening and Hit Validation of Extracellular-Related Kinase 5 (ERK5) Inhibitors.

    Science.gov (United States)

    Myers, Stephanie M; Bawn, Ruth H; Bisset, Louise C; Blackburn, Timothy J; Cottyn, Betty; Molyneux, Lauren; Wong, Ai-Ching; Cano, Celine; Clegg, William; Harrington, Ross W; Leung, Hing; Rigoreau, Laurent; Vidot, Sandrine; Golding, Bernard T; Griffin, Roger J; Hammonds, Tim; Newell, David R; Hardcastle, Ian R

    2016-08-08

    The extracellular-related kinase 5 (ERK5) is a promising target for cancer therapy. A high-throughput screen was developed for ERK5, based on the IMAP FP progressive binding system, and used to identify hits from a library of 57 617 compounds. Four distinct chemical series were evident within the screening hits. Resynthesis and reassay of the hits demonstrated that one series did not return active compounds, whereas three series returned active hits. Structure-activity studies demonstrated that the 4-benzoylpyrrole-2-carboxamide pharmacophore had excellent potential for further development. The minimum kinase binding pharmacophore was identified, and key examples demonstrated good selectivity for ERK5 over p38α kinase.

  2. Trees as environmental modifier to improve street canyon for pedestrian activities in Muscat

    Science.gov (United States)

    Khudhayer, Wael A.; Shaaban, Awni K.; Sukor, Nur Sabahiah Abdul

    2017-10-01

    Street shading efficiency is a function of orientation and profile proportion of its height to width. Under high sun altitude conditions, minimization of solar irradiance within the urban environment may often be a significant criterion in urban design. This reduction in solar irradiance achieved when the obstruction angle is large (high H/W ratio, H=height, W=width). High H/W values often lessen the solar access to streets. The horizontal sprawl of Muscat region is an example of low H/W ratio represented the remarkable challenge that causes the lack of shading rates in the urban street. This characteristic proliferates the negative impact on the pedestrian activities in the urban street. This research aims to improve the morphology of the street to promote the pedestrian behavior. The amendment based on suggesting different configurations of trees to increase effective shading of the urban street in Muscat. The street canyon abstracted into a virtual elongated channel formed of floor and walls of equal heights on both sides. Four street orientations (E/W, N/S, NE/SW, NW/SE) and three H/W ratio (0.5,1 and 2) are considered sufficient representative of street typologies. A mathematical model developed for calculation of shading efficiency of each street canyon. The trees assumed in this study as canyon's modifier to adjust the low H/W ratio of a street canyon to a higher one. Local trees and other plants in Muscat were studied concerning their morphology. The analysis selected two case study in Muscat to investigate the shading performance of their street canyons subsequently propose the modifications to improve it. The research concluded that the suggested changes of the street canyon by using a particular type of trees could increase the H/W ratio of street canyon significantly.

  3. CURB-BASED STREET FLOOR EXTRACTION FROM MOBILE TERRESTRIAL LIDAR POINT CLOUD

    Directory of Open Access Journals (Sweden)

    S. Ibrahim

    2012-07-01

    Full Text Available Mobile terrestrial laser scanners (MTLS produce huge 3D point clouds describing the terrestrial surface, from which objects like different street furniture can be generated. Extraction and modelling of the street curb and the street floor from MTLS point clouds is important for many applications such as right-of-way asset inventory, road maintenance and city planning. The proposed pipeline for the curb and street floor extraction consists of a sequence of five steps: organizing the 3D point cloud and nearest neighbour search; 3D density-based segmentation to segment the ground; morphological analysis to refine out the ground segment; derivative of Gaussian filtering to detect the curb; solving the travelling salesman problem to form a closed polygon of the curb and point-inpolygon test to extract the street floor. Two mobile laser scanning datasets of different scenes are tested with the proposed pipeline. The results of the extracted curb and street floor are evaluated based on a truth data. The obtained detection rates for the extracted street floor for the datasets are 95% and 96.53%. This study presents a novel approach to the detection and extraction of the road curb and the street floor from unorganized 3D point clouds captured by MTLS. It utilizes only the 3D coordinates of the point cloud.

  4. Street Cries and the urban refrain

    DEFF Research Database (Denmark)

    Kreutzfeldt, Jacob

    2012-01-01

    Rasmussen have investigated Danish street cries as respectably a musical and a spatial phenomenon. Such studies – from each their perspectives – can be said to explore the aesthetics of urban environments, since street calls are specifically developed and heard in the context of the city. Investigating...... the different methods employed in the two studies and presenting Deleuze and Guattaris theory about the refrain as a framework for further studies in the field, this article seeks to outline a fertile area of study for sound studies: the investigation of everyday refrains and the environmental relations...

  5. Upgrade tracking with the UT Hits

    CERN Document Server

    Gandini, P; Wang, J

    2014-01-01

    The performance of the LHCb tracking system for the upgrade on long tracks is evaluated in terms of efficiency and ghost rate reduction for several different sets of requirements. We find that the efficiency is quite high and that the ghost rate reduction is substantial. We also describe the current algorithm for adding UT hits to the tracks.

  6. Trees in the city: valuing street trees in Portland, Oregon

    Science.gov (United States)

    G.H. Donovan; D.T. Butry

    2010-01-01

    We use a hedonic price model to simultaneously estimate the effects of street trees on the sales price and the time-on-market (TOM) of houses in Portland. Oregon. On average, street trees add $8,870 to sales price and reduce TOM by 1.7 days. In addition, we found that the benefits of street trees spill over to neighboring houses. Because the provision and maintenance...

  7. Relationships as determinants of substance use amongst street ...

    African Journals Online (AJOL)

    Background: Unrestrained exposure to street life often makes the street child vulnerable to psychoactive substances. In other settings, the social relationships of the substance user with those around him or her and family norms of parenting have been docu-mented to modulate use. However, there is a dearth of literature on ...

  8. The Influence of Vegetation Function towards the Langsep Street Thermal Comfort

    Science.gov (United States)

    Alfian, R.; Setyabudi, I.; Uran, R. S.

    2017-10-01

    Streetscape is an important element for character building of the environment, spatial, and visual in order to provide an urban identity, especially in Malang City protocol streets. Langsep Street is one of the protocol streets in Malang City. Langsep Street famous with central education and offices area. This study aims (1) to identify vegetation of streetscape; (2) to analyze the thermal comfort of the streetscape, and (3) to evaluate the comfort level of Langsep Street. The method used was the THI approach. THI value that obtained was analyzed using the standard of Laurie (1990). Based on observations, the THI value of Langsep Street was 27.60. This was influenced by the trees canopy density and spacing of the trees on the streetscape. It can be concluded that streetscape required (1) shaded plants that have root systems that do not damage the construction of roads, (2) the branching plants are not easily broken and easy to maintain, and (3) the combination of trees, shrubs and ground cover.

  9. The Ballet of the Streets: Teaching about Cities at Street Level

    Science.gov (United States)

    McGuire, Patrick A.; Spates, James L.

    2011-01-01

    The urban scholar Jane Jacobs once described city life as "the ballet of the streets." In more than a quarter century of joint teaching, the authors have used Jacobs' metaphor to help their students understand that cities are living organisms created and maintained, for good or ill, by the people who live and work in them. At heart their…

  10. LncRNA-HIT Functions as an Epigenetic Regulator of Chondrogenesis through Its Recruitment of p100/CBP Complexes.

    Science.gov (United States)

    Carlson, Hanqian L; Quinn, Jeffrey J; Yang, Yul W; Thornburg, Chelsea K; Chang, Howard Y; Stadler, H Scott

    2015-12-01

    Gene expression profiling in E 11 mouse embryos identified high expression of the long noncoding RNA (lncRNA), LNCRNA-HIT in the undifferentiated limb mesenchyme, gut, and developing genital tubercle. In the limb mesenchyme, LncRNA-HIT was found to be retained in the nucleus, forming a complex with p100 and CBP. Analysis of the genome-wide distribution of LncRNA-HIT-p100/CBP complexes by ChIRP-seq revealed LncRNA-HIT associated peaks at multiple loci in the murine genome. Ontological analysis of the genes contacted by LncRNA-HIT-p100/CBP complexes indicate a primary role for these loci in chondrogenic differentiation. Functional analysis using siRNA-mediated reductions in LncRNA-HIT or p100 transcripts revealed a significant decrease in expression of many of the LncRNA-HIT-associated loci. LncRNA-HIT siRNA treatments also impacted the ability of the limb mesenchyme to form cartilage, reducing mesenchymal cell condensation and the formation of cartilage nodules. Mechanistically the LncRNA-HIT siRNA treatments impacted pro-chondrogenic gene expression by reducing H3K27ac or p100 activity, confirming that LncRNA-HIT is essential for chondrogenic differentiation in the limb mesenchyme. Taken together, these findings reveal a fundamental epigenetic mechanism functioning during early limb development, using LncRNA-HIT and its associated proteins to promote the expression of multiple genes whose products are necessary for the formation of cartilage.

  11. Retrospective assessment of occupational asbestos exposure among 220 patients with respiratory cancer hospitalized at Vilnius University Institute of Oncology

    International Nuclear Information System (INIS)

    Petrauskaite Everatt, R.; Jankauskas, R.; Tossavainen, A.; Cicenas, S.; Smolianskiene, G.

    2005-01-01

    No cases of lung cancer or mesothelioma have ever been diagnosed or compensated as asbestos-related in Lithuania. This paper attempts to estimate the proportion of those occupationally exposed to asbestos among respiratory cancer patients. Occupational exposure to asbestos was assessed retrospectively for 218 lung cancer and 2 mesothelioma patients admitted to Institute of Oncology, Vilnius University. The evaluation was based on personal interview data using an internationally established questionnaire. Cumulative exposure to asbestos at work was evaluated in fibre-years. A cumulative asbestos exposure of ≥25 fibre-years was found for 7 patients (3.2%), in further 135 (61.2%) a cumulative exposure from 0.01 to 24.99 fibre-years was assessed. The most common occupations among heavily (≥25 fibre-years) exposed patients were smith, welder or insulator in foundries, construction, shipyard as well as asbestos cement and glass industry. Preliminary findings indicate that a fraction (3.2%) of the respiratory cancer cases could be attributed to occupational exposure to asbestos. Since 1560 or more cases of lung cancer are registered every year in Lithuania, about 50 cases per year could be predicted to be asbestos-related. (author)

  12. Solar radiation and street temperature as function of street orientation. An analysis of the status quo and simulation of future scenarios towards sustainability in Bahrain

    Directory of Open Access Journals (Sweden)

    Silva Joao Pinelo

    2017-01-01

    A countrywide analysis shows that E-W orientation accounts for the highest overall street length with 37%. The second most frequent orientation is N-S (29%, the best performer. NW-SE and NE-SW both have frequencies of only 17%. Preference for a street grid with N-S, NW-SE, and NE-SW orientation would improve the thermal performance of streets and provide a continuous network of a comfortable pedestrian environment. We simulate two future scenarios based on avoiding new E-W streets, or not. We measure their potential reduction in thermal gain and conclude that a simple policy could reduce solar exposition in 40%.

  13. Renaming Zagreb Streets and Squares

    Directory of Open Access Journals (Sweden)

    Jelena Stanić

    2009-06-01

    Full Text Available The paper deals with changes in street names in the city of Zagreb. Taking the Lower Town (Donji grad city area as an example, the first part of the paper analyses diachronic street name changes commencing from the systematic naming of streets in 1878. Analysis of official changes in street names throughout Zagreb’s history resulted in categorisation of five periods of ideologically motivated naming/name-changing: 1. the Croatia modernisation period, when the first official naming was put into effect, with a marked tendency towards politicisation and nationalisation of the urban landscape; 2. the period of the Kingdom of the Serbs, Croatians and Slovenians/Yugoslavia, when symbols of the new monarchy, the idea of the fellowship of the Southern Slavs, Slavenophilism and the pro-Slavic geopolitical orientation were incorporated into the street names, and when the national idea was highly evident and remained so in that process; 3. the period of the NDH, the Independent State of Croatia, with decanonisation of the tokens of the Yugoslavian monarchy and the Southern Slavic orientation, and reference to the Ustashi and the German Nazi and Italian Fascist movement; 4. the period of Socialism, embedding the ideals and heroes of the workers’ movement and the War of National Liberation into the canonical system; and, 5. the period following the democratic changes in 1990, when almost all the signs of Socialism and the Communist/Antifascist struggle were erased, with the prominent presence of a process of installing new references to early national culture and historical tradition. The closing part of the paper deals with public discussions connected with the selection of a location for a square to bear the name of the first president of independent Croatia, Franjo Tuđman. Analysis of these public polemics shows two opposing discourses: the right-wing political option, which supports a central position for the square and considers the chosen area to

  14. Tobacco Taxation, Smuggling, and Street Tobacco Vendors in Eritrea

    International Development Research Centre (IDRC) Digital Library (Canada)

    The bulk of the smuggled cigarettes are sold by street vendors, many of them women and children, ... and its implications for government revenue;; identify the reasons why people sell on the streets; and, ... Agent(e) responsable du CRDI.

  15. Evaluation of flow cytometric HIT assays in relation to an IgG-Specific immunoassay and clinical outcome.

    Science.gov (United States)

    Kerényi, Adrienne; Beke Debreceni, Ildikó; Oláh, Zsolt; Ilonczai, Péter; Bereczky, Zsuzsanna; Nagy, Béla; Muszbek, László; Kappelmayer, János

    2017-09-01

    Heparin-induced thrombocytopenia (HIT) is a severe side effect of heparin treatment caused by platelet activating IgG antibodies generated against the platelet factor 4 (PF4)-heparin complex. Thrombocytopenia and thrombosis are the leading clinical symptoms of HIT. The clinical pretest probability of HIT was evaluated by the 4T score system. Laboratory testing of HIT was performed by immunological detection of antibodies against PF4-heparin complex (EIA) and two functional assays. Heparin-dependent activation of donor platelets by patient plasma was detected by flow cytometry. Increased binding of Annexin-V to platelets and elevated number of platelet-derived microparticles (PMP) were the indicators of platelet activation. EIA for IgG isotype HIT antibodies was performed in 405 suspected HIT patients. Based on negative EIA results, HIT was excluded in 365 (90%) of cases. In 40 patients with positive EIA test result functional tests were performed. Platelet activating antibodies were detected in 17 cases by Annexin V binding. PMP count analysis provided nearly identical results. The probability of a positive flow cytometric assay result was higher in patients with elevated antibody titer. 71% of patients with positive EIA and functional assay had thrombosis. EIA is an important first line laboratory test in the diagnosis of HIT; however, HIT must be confirmed by a functional test. Annexin V binding and PMP assays using flow cytometry are functional HIT tests convenient in a clinical diagnostic laboratory. The positive results of functional assays may predict the onset of thrombosis. © 2016 International Clinical Cytometry Society. © 2016 International Clinical Cytometry Society.

  16. Exploring the World using Street View 360 Images

    Science.gov (United States)

    Bailey, J.

    2016-12-01

    The phrase "A Picture is Worth a Thousand Words" is an idiom of unknown 20th century origin. There is some belief that the modern use of the phrase stems from an article in a 1921 issue of a popular trade journal, that used "One Look is Worth A Thousand Words" to promote the use of images in advertisements on the sides of streetcars. There is a certain irony to this as nearly a century later the camera technologies on "Street View cars" are collecting images that look everywhere at once. However, while it can be to fun drive along the World's streets, it was the development of Street View imaging systems that could be mounted on other modes of transport or capture platforms (Street View Special Collects) that opened the door for these 360 images to become a tool for exploration and storytelling. Using Special Collect imagery captured in "off-road" and extreme locations, scientists are now using Street View images to assess changes to species habitats, show the impact of natural disasters and even perform "armchair" geology. A powerful example is the imagery captured before and after the 2011 earthquake and tsunami that devastated Japan. However, it is use of the immersive nature of 360 images that truly allows them to create wonder and awe, especially when combined with Virtual Reality (VR) viewers. Combined with the Street View App or Google Expeditions, VR provides insight into what it is like to swim with sealions in the Galapagos or climb El Capitan in Yosemite National Park. While these image could never replace experiencing these locations in real-life, they can inspire the viewer to explore and learn more about the many wonders of our planet. https://www.google.com/streetview/https://www.google.com/expeditions/

  17. Possilibity of estimating payoff matrix from model for hit phenomena

    International Nuclear Information System (INIS)

    Ishii, Akira; Sakaidani, Shota; Iwanaga, Saori

    2016-01-01

    The conflicts of topics on social media is considered using an extended mathematical model based on the mathematical model for hit phenomena that has been used to analyze entertainment hits. The social media platform used in this study was blog. The calculation results shows examples of strong conflict, weak conflict, and no conflict cases. Since the conflict of two topics can be considered in the framework of game theory, the results can be used to determine each matrix element of the payoff matrix of game theory.

  18. Wind-induced single-sided natural ventilation in buildings near a long street canyon: CFD evaluation of street configuration and envelope design

    DEFF Research Database (Denmark)

    Ai, Z.T.; Mak, C.M.

    2018-01-01

    an urban context, this study investigates the wind-induced single-sided natural ventilation in buildings near a long street canyon under a perpendicular wind direction using CFD method. Four aspect ratios (AR) of the street canyon, from 1.0, 2.0, 4.0 to 6.0, are investigated to examine the influence...

  19. MAINTENANCE OF THE CARPARK AND STREET LIGHTING

    CERN Multimedia

    ST-FM Group

    2002-01-01

    The ST Division informs you that the control and maintenance of the carpark and street lighting will be carried out during the next few weeks. These lightings work normally by photocells but during these tests they will be turned on zone by zone during the day. So we ask the users not to be surprised to see the street lighting on during the day and thank them for their comprehension. ST-FM Group

  20. Designing safe and inclusive streets in India | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2016-11-17

    Nov 17, 2016 ... In fast-growing Indian cities such as Ahmedabad, streets are also the site of conflict. ... while instances of violence against women are partly linked to land ... by poor street design, and to develop people-centred alternatives.

  1. Influence of local parameters on the dispersion of traffic-related pollutants within street canyons

    Science.gov (United States)

    Karra, Styliani; Malki-Epshtein, Liora; Martin Hyde Collaboration

    2011-11-01

    Ventilation within urban cities and street canyons and the associated air quality is a problem of increasing interest in the last decades. It is important for to minimise exposure of the population to traffic-related pollutants at street level. The residence time of pollutants within the street canyons depends on the meteorological conditions such as wind speed and direction, geometry layout and local parameters (position of traffic lane within the street). An experimental study was carried out to investigate the influence of traffic lane position on the dispersion of traffic-related pollutants within different street canyons geometries: symmetrical (equal building heights on both sides of the street), non-symmetrical (uniform building heights but lower on one side of the street) and heterogeneous (non-uniform building heights on both sides of the street) under constant meteorological conditions. Laboratory experiments were carried out within a water channel and simultaneous measurements of velocity field and concentration scalar levels within and above the street canyons using PIV and PLIF techniques. Traffic -related emissions were simulated using a line emission source. Two positions were examined for all street geometries: line emission source was placed in the centre of the street canyon; line emission source was placed off the centre of the street. TSI Incorporated.

  2. Street trees reduce the negative effects of urbanization on birds.

    Science.gov (United States)

    Pena, João Carlos de Castro; Martello, Felipe; Ribeiro, Milton Cezar; Armitage, Richard A; Young, Robert J; Rodrigues, Marcos

    2017-01-01

    The effects of streets on biodiversity is an important aspect of urban ecology, but it has been neglected worldwide. Several vegetation attributes (e.g. street tree density and diversity) have important effects on biodiversity and ecological processes. In this study, we evaluated the influences of urban vegetation-represented by characteristics of street trees (canopy size, proportion of native tree species and tree species richness)-and characteristics of the landscape (distance to parks and vegetation quantity), and human impacts (human population size and exposure to noise) on taxonomic data and functional diversity indices of the bird community inhabiting streets. The study area was the southern region of Belo Horizonte (Minas Gerais, Brazil), a largely urbanized city in the understudied Neotropical region. Bird data were collected on 60 point count locations distributed across the streets of the landscape. We used a series of competing GLM models (using Akaike's information criterion for small sample sizes) to assess the relative contribution of the different sets of variables to explain the observed patterns. Seventy-three bird species were observed exploiting the streets: native species were the most abundant and frequent throughout this landscape. The bird community's functional richness and Rao's Quadratic Entropy presented values lower than 0.5. Therefore, this landscape was favoring few functional traits. Exposure to noise was the most limiting factor for this bird community. However, the average size of arboreal patches and, especially the characteristics of street trees, were able to reduce the negative effects of noise on the bird community. These results show the importance of adequately planning the urban afforestation process: increasing tree species richness, preserving large trees and planting more native trees species in the streets are management practices that will increase bird species richness, abundance and community functional aspects and

  3. A Solution for Street Lighting in Smart Cities

    Directory of Open Access Journals (Sweden)

    M. Popa

    2012-06-01

    Full Text Available Smart Cities is a domain of great interest in the modern society. The aim of a smart urban environment is to increase citizens’ comfort and quality of life with minimum resources and power consumption and without affecting the natural environment. Street lighting is one of the main interests in such a smart environment. This thesis focuses on implementing a lighting control system that makes street lighting to be an autonomous and efficient part of the urban environment. The performance of the proposed system is analyzed using an OMNET++ network simulation. The results lead to the conclusion that the smart control system improves some drawbacks of a classic street lighting system.

  4. Impacts of Street-Visible Greenery on Housing Prices: Evidence from a Hedonic Price Model and a Massive Street View Image Dataset in Beijing

    Directory of Open Access Journals (Sweden)

    Yonglin Zhang

    2018-03-01

    Full Text Available Street greenery is a component of urban green infrastructure. By forming foundational green corridors in urban ecological systems, street greenery provides vital ecological, social, and cultural functions, and benefits the wellbeing of citizens. However, because of the difficulty of quantifying people’s visual perceptions, the impact of street-visible greenery on housing prices has not been fully studied. Using Beijing, which has a mature real estate market, as an example, this study evaluated 22,331 transactions in 2014 in 2370 private housing estates. We selected 25 variables that were classified into three categories—location, housing, and neighbourhood characteristics—and introduced an index called the horizontal green view index (HGVI into a hedonic pricing model to measure the value of the visual perception of street greenery in neighbouring residential developments. The results show that (1 Beijing’s homebuyers would like to reside in residential units with a higher HGVI; (2 Beijing’s homebuyers favour larger lakes; and (3 Beijing’s housing prices were impacted by the spatial development patterns of the city centre and multiple business centres. We used computer vision to quantify the street-visible greenery and estimated the economic benefits that the neighbouring visible greenery would have on residential developments in Beijing. This study provides a scientific basis and reference for policy makers and city planners in road greening, and a tool for formulating street greening policy, studying housing price characteristics, and evaluating real estate values.

  5. Land Use Correlates of Street Children in Ogbomoso, Nigeria

    African Journals Online (AJOL)

    There exist many locations in which street children are found: public spheres such as markets, bus stops, car parks, garages, street corners, and under the bridges .... attributes of space such as form, pattern and aspect and are descriptive in ...

  6. Do urban canyons influence street level grass pollen concentrations?

    DEFF Research Database (Denmark)

    Peel, Robert George; Kennedy, Roy; Smith, Matt

    2014-01-01

    In epidemiological studies, outdoor exposure to pollen is typically estimated using rooftop monitoring station data, whilst exposure overwhelmingly occurs at street level. In this study the relationship between street level and roof level grass pollen concentrations was investigated for city cent...

  7. Visual Illusions and the Control of Ball Placement in Goal-Directed Hitting

    Science.gov (United States)

    Caljouw, Simone R.; Van der Kamp, John; Savelsbergh, Geert J. P.

    2010-01-01

    When hitting, kicking, or throwing balls at targets, online control in the target area is impossible. We assumed this lack of late corrections in the target area would induce an effect of a single-winged Muller-Lyer illusion on ball placement. After extensive practice in hitting balls to different landing locations, participants (N = 9) had to hit…

  8. NUTRIENTS INTAKE AND NUTRITIONAL STATUS OF STREET CHILDREN IN BANDUNG

    Directory of Open Access Journals (Sweden)

    Rita Patriasih

    2012-03-01

    Full Text Available 800x600 Normal 0 false false false IN X-NONE X-NONE MicrosoftInternetExplorer4 The objectives of this research were to analyze food habits and nutrients intake, and health and nutritional status of street children. The research was carried out in the City of Bandung, West Java; Indonesia. A sample of 324 street children was selected randomly. The sample consisted of 232 boys and 92 girls. The data obtained from questionnaires. Means, standard deviation, frequency and proportion were calculated with a combination of software applications:  Microsoft Excel and Statistical Analysis System. The result showed the level of consumption adequacy did not meet the recommended dietary allowances i.e. with the shortage of 10-15%, this is an indication that the street children should be aware of their daily food consumption. The most common diseases suffered by the respondents were acute respiratory infections (ARI (47%. In addition, 22.7 % and 18.4 % of them suffered from diarrhoea and skin diseases, respectively. Blood haemoglobin status of street children shows that the incidence of anemia was 29.3%. Based on the classification of nutritional status, 42.7% and 80.4 % of street children were underweight and stunted, respectively. Key words: nutrients intake, nutritional status, street children

  9. Aggressive B cell Lymphoma: Optimal Therapy for MYC-positive, Double-Hit, and Triple-Hit DLBCL.

    Science.gov (United States)

    Dunleavy, Kieron

    2015-12-01

    Approximately 10% of cases of diffuse large B cell lymphoma (DLBCL) harbor a MYC rearrangement and this has been associated with an inferior outcome following standard therapy across many different studies. Double-hit and triple-hit lymphomas harbor concurrent rearrangements of MYC and BCL2 and/or BCL6 and are also associated with a very aggressive course and poor clinical outcome. It is unclear and there is lack of consensus on how these diseases should be approached therapeutically. They are characterized typically by high tumor proliferation and likely require Burkitt lymphoma-type strategies and several retrospective studies suggest that more intensive approaches than rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) may be beneficial. One challenge in this respect is that most patients with these diseases are older than 60 years and generally have poor tolerability of regimens typically used in Burkitt lymphoma. Dose-adjusted EPOCH-R is an alternative effective immunochemotherapy platform for DLBCL and is effective in Burkitt lymphoma, and retrospective studies suggest that it is effective and feasible in patients with DLBCL that harbors a MYC rearrangement with or without a BCL-2 translocation (double-hit). A multicenter study of this approach in MYC-rearranged DLBCL is ongoing and preliminary results are very encouraging. There is a lack of consensus on the role of consolidation stem cell transplantation in patients who achieve a good response to initial therapy but at this point in time, no (retrospective) studies have demonstrated any benefit. These diseases are also associated with a high rate of CNS involvement and progression and checking for cerebrospinal fluid by cytology and flow cytometry at initial diagnosis should be considered. In summary, based on retrospective data and preliminary prospective data (as more mature data is awaited), while Burkitt-type regimens may be feasible in young patients, DA-EPOCH-R is a

  10. Green Street in District of Columbia Curbs Harmful Runoff

    Science.gov (United States)

    The name of the block hasn’t been changed to “Oh!” Street, but a revamped section of O Street NW in the District of Columbia is turning heads with green features that are keeping stormwater pollution out of the Anacostia River.

  11. The levels and patterns of resilience among male street children in Dhaka City.

    Science.gov (United States)

    Sayem, Amir M; Kidd, Sean A

    2013-01-01

    Abstract This study was carried out to identify the factors affecting resilience among street children. The study used a convenience sample of 366 male street children aged 14-17 years in Dhaka City, Bangladesh. The levels of resilience among the street children were mostly moderately low-low (54.1%), followed by low (29.0%), and moderately high-high resilience (16.9%). Multinomial logistic regression analyses indicated that the pre-street factors of education, economic constraint in the family, as well as experiencing and witnessing domestic violence were associated with resilience, with associated street characteristics being drug abuse, experiencing and witnessing violence on street, access to prevention services, and political involvement.

  12. Simulation optimizing of n-type HIT solar cells with AFORS-HET

    Science.gov (United States)

    Yao, Yao; Xiao, Shaoqing; Zhang, Xiumei; Gu, Xiaofeng

    2017-07-01

    This paper presents a study of heterojunction with intrinsic thin layer (HIT) solar cells based on n-type silicon substrates by a simulation software AFORS-HET. We have studied the influence of thickness, band gap of intrinsic layer and defect densities of every interface. Details in mechanisms are elaborated as well. The results show that the optimized efficiency reaches more than 23% which may give proper suggestions to practical preparation for HIT solar cells industry.

  13. A bicycle safety index for evaluating urban street facilities.

    Science.gov (United States)

    Asadi-Shekari, Zohreh; Moeinaddini, Mehdi; Zaly Shah, Muhammad

    2015-01-01

    The objectives of this research are to conceptualize the Bicycle Safety Index (BSI) that considers all parts of the street and to propose a universal guideline with microscale details. A point system method comparing existing safety facilities to a defined standard is proposed to estimate the BSI. Two streets in Singapore and Malaysia are chosen to examine this model. The majority of previous measurements to evaluate street conditions for cyclists usually cannot cover all parts of streets, including segments and intersections. Previous models also did not consider all safety indicators and cycling facilities at a microlevel in particular. This study introduces a new concept of a practical BSI to complete previous studies using its practical, easy-to-follow, point system-based outputs. This practical model can be used in different urban settings to estimate the level of safety for cycling and suggest some improvements based on the standards.

  14. Pühendusega isadele - Baker Street

    Index Scriptorium Estoniae

    2009-01-01

    Üritusest 7. novembril Kuressaares Arensburg lounge-restoranis Muusa toimuvast isadepäevahõngulisest üritusest, esinevad Virgo Veldi & Band kavaga "Baker Street", erikülalisena Villu Veski. Saksofonistist Virgo Veldist

  15. History of the Botanic Garden of the Stefan Batory University in Vilna (Vilnius (1919–1939 (in Polish

    Directory of Open Access Journals (Sweden)

    Alicja Zemanek

    2016-11-01

    Full Text Available The university in Vilna (Lithuanian: Vilnius, now Vilniaus universitetas, founded in 1579 by Stefan Batory (Stephen Báthory, King of Poland and Grand Duke of Lithuania, was a centre of Polish botany in 1780-1832 and 1919-1939. The Botanic Garden established by Jean-Emmanuel Gilibert (1741–1814 in 1781 (or, actually, from 1782 survived the loss of independence by Poland (1795, and a later closure of the University (1832, and it continued to function until 1842, when it was shut down by Russian authorities. After Poland had regained independence and the University was reopened as the Stefan Batory University (SBU, its Botanic Garden was established on a new location (1919, active since 1920. It survived as a Polish institution until 1939. After the Second World War, as a result of changed borders, it found itself in the Soviet Union, and from 1990 – in the Republic of Lithuania. A multidisciplinary research project has been recently launched with the aim to create a publication on the history of science at the Stefan Batory University. The botanical part of the project includes, among others, drafting the history of the Botanic Garden. Obtaining electronic copies of archival documents, e.g. annual reports written by the directors, enabled a more thorough analysis of the Garden’s history. Piotr Wiśniewski (1884–1971, a plant physiologist, nominated as Professor in the Department of General Botany on 1 June 1920, was the organiser and the first director of the Garden. He resigned from his post in October 1923, due to financial problems of the Garden. From October 1923 to April 1924, the management was run by the acting director, Edward Bekier (1883–1945, Professor in the Department of Physical Chemistry, Dean of the Faculty of Mathematics and Natural Sciences. For 13 subsequent years, i.e. from 1 May 1924 to 30 April 1937, the directorship of the Garden was held by Józef Trzebiński (1867–1941, a mycologist and one of the pioneers of

  16. Multi-scale modeling of urban air pollution: development of a Street-in-Grid model

    Science.gov (United States)

    Kim, Youngseob; Wu, You; Seigneur, Christian; Roustan, Yelva

    2016-04-01

    A new multi-scale model of urban air pollution is presented. This model combines a chemical-transport model (CTM) that includes a comprehensive treatment of atmospheric chemistry and transport at spatial scales greater than 1 km and a street-network model that describes the atmospheric concentrations of pollutants in an urban street network. The street-network model is based on the general formulation of the SIRANE model and consists of two main components: a street-canyon component and a street-intersection component. The street-canyon component calculates the mass transfer velocity at the top of the street canyon (roof top) and the mean wind velocity within the street canyon. The estimation of the mass transfer velocity depends on the intensity of the standard deviation of the vertical velocity at roof top. The effect of various formulations of this mass transfer velocity on the pollutant transport at roof-top level is examined. The street-intersection component calculates the mass transfer from a given street to other streets across the intersection. These mass transfer rates among the streets are calculated using the mean wind velocity calculated for each street and are balanced so that the total incoming flow rate is equal to the total outgoing flow rate from the intersection including the flow between the intersection and the overlying atmosphere at roof top. In the default option, the Leighton photostationary cycle among ozone (O3) and nitrogen oxides (NO and NO2) is used to represent the chemical reactions within the street network. However, the influence of volatile organic compounds (VOC) on the pollutant concentrations increases when the nitrogen oxides (NOx) concentrations are low. To account for the possible VOC influence on street-canyon chemistry, the CB05 chemical kinetic mechanism, which includes 35 VOC model species, is implemented in this street-network model. A sensitivity study is conducted to assess the uncertainties associated with the use of

  17. Assessment of the performances of AcuStar HIT and the combination with heparin-induced multiple electrode aggregometry: a retrospective study.

    Science.gov (United States)

    Minet, V; Bailly, N; Douxfils, J; Osselaer, J C; Laloy, J; Chatelain, C; Elalamy, I; Chatelain, B; Dogné, J M; Mullier, F

    2013-09-01

    Early diagnosis of immune heparin-induced thrombocytopenia (HIT) is challenging. HemosIL® AcuStar HIT and heparin-induced multiple electrode aggregometry (HIMEA) were recently proposed as rapid diagnostic methods. We conducted a study to assess performances of AcuStar HIT-IgG (PF4-H) and AcuStar HIT-Ab (PF4-H). The secondary objective was to compare the performances of the combination of Acustar HIT and HIMEA with standardised clinical diagnosis. Sera of 104 suspected HIT patients were retrospectively tested with AcuStar HIT. HIMEA was performed on available sera (n=81). The clinical diagnosis was established by analysing in a standardized manner the patient's medical records. These tests were also compared with PF4-Enhanced®, LTA, and SRA in subsets of patients. Thresholds were determined using ROC curve analysis with clinical outcome as reference. Using the recommended thresholds (1.00AU), the negative predictive value (NPV) of HIT-IgG and HIT-Ab were 100.0% (95% CI: 95.9%-100.0% and 95.7%-100.0%). The positive predictive value (PPV) were 64.3% (95% CI: 35.1%-87.2.2%) and 45.0% (95% CI: 23.2%-68.6%), respectively. Using our thresholds (HIT-IgG: 2.89AU, HIT-Ab: 9.41AU), NPV of HIT-IgG and HIT-Ab were 100.0% (95% CI: 96.0%-100.0% and 96.1%-100.0%). PPV were 75.0% (95% CI: 42.7%-94.5%) and 81.8% (95% CI: 48.3%-97.7%), respectively. Of the 79 patients with a medium-high pretest probability score, 67 were negative using HIT-IgG (PF4-H) test at our thresholds. HIMEA was performed on HIT-IgG positive patients. Using this combination, only one patient on 79 was incorrectly diagnosed. Acustar HIT showed good performances to exclude the diagnosis of HIT. Combination with HIMEA improves PPV. Copyright © 2013 Elsevier Ltd. All rights reserved.

  18. Smart street lighting management

    Energy Technology Data Exchange (ETDEWEB)

    Pizzuti, S.; Annunziato, M. [Energy New Technologies and Sustainable Economic Development Agency ENEA, Rome (Italy); Moretti, F. [Automation and Computer Science Department, University & #x27; Roma Tre& #x27; , Rome (Italy)

    2013-08-15

    In this work, we propose a new street lighting energy management system in order to reduce energy consumption. The key idea we want to accomplish is that of 'energy on demand' meaning that energy, in this case light, is provided only when needed. In order to achieve this goal, it is critical to have a reliable demand model, which in the case of street lighting turns out to be a traffic flow rate forecasting model. In order to achieve this goal, several methods on the 1-h prediction have been compared and the one providing the best results is based on artificial neural networks. Moreover, several control strategies have been tested and the one which gave the best energy savings is the adaptive one we carried out. Experimentation has been carried out on real data and the study shows that with the proposed approach, it is possible to save up to 50 % of energy compared to no regulation systems.

  19. Playing Sport In The Stormy Sea Of Street Life | Human | African ...

    African Journals Online (AJOL)

    Currently, there are many street children in South Africa (SA). They have been robbed from the safe harbour of family life and on a daily basis experience the stormy sea of street life. Society has an obligation to intervene in the lives of these street children through, for example, quality education, basic health services and ...

  20. Travel Time Estimation on Urban Street Segment

    Directory of Open Access Journals (Sweden)

    Jelena Kajalić

    2018-02-01

    Full Text Available Level of service (LOS is used as the main indicator of transport quality on urban roads and it is estimated based on the travel speed. The main objective of this study is to determine which of the existing models for travel speed calculation is most suitable for local conditions. The study uses actual data gathered in travel time survey on urban streets, recorded by applying second by second GPS data. The survey is limited to traffic flow in saturated conditions. The RMSE method (Root Mean Square Error is used for research results comparison with relevant models: Akcelik, HCM (Highway Capacity Manual, Singapore model and modified BPR (the Bureau of Public Roads function (Dowling - Skabardonis. The lowest deviation in local conditions for urban streets with standardized intersection distance (400-500 m is demonstrated by Akcelik model. However, for streets with lower signal density (<1 signal/km the correlation between speed and degree of saturation is best presented by HCM and Singapore model. According to test results, Akcelik model was adopted for travel speed estimation which can be the basis for determining the level of service in urban streets with standardized intersection distance and coordinated signal timing under local conditions.

  1. Reconstruction of hit time and hit position of annihilation quanta in the J-PET detector using the Mahalanobis distance

    Directory of Open Access Journals (Sweden)

    Sharma Neha Gupta

    2015-12-01

    Full Text Available The J-PET detector being developed at the Jagiellonian University is a positron emission tomograph composed of the long strips of polymer scintillators. At the same time, it is a detector system that will be used for studies of the decays of positronium atoms. The shape of photomultiplier signals depends on the hit time and hit position of the gamma quantum. In order to take advantage of this fact, a dedicated sampling front-end electronics that enables to sample signals in voltage domain with the time precision of about 20 ps and novel reconstruction method based on the comparison of examined signal with the model signals stored in the library has been developed. As a measure of the similarity, we use the Mahalanobis distance. The achievable position and time resolution depend on the number and values of the threshold levels at which the signal is sampled. A reconstruction method as well as preliminary results are presented and discussed.

  2. Pecan Street Grid Demonstration Program. Final technology performance report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2015-02-10

    This document represents the final Regional Demonstration Project Technical Performance Report (TPR) for Pecan Street Inc.’s (Pecan Street) Smart Grid Demonstration Program, DE-OE-0000219. Pecan Street is a 501(c)(3) smart grid/clean energy research and development organization headquartered at The University of Texas at Austin (UT). Pecan Street worked in collaboration with Austin Energy, UT, Environmental Defense Fund (EDF), the City of Austin, the Austin Chamber of Commerce and selected consultants, contractors, and vendors to take a more detailed look at the energy load of residential and small commercial properties while the power industry is undergoing modernization. The Pecan Street Smart Grid Demonstration Program signed-up over 1,000 participants who are sharing their home or businesses’s electricity consumption data with the project via green button protocols, smart meters, and/or a home energy monitoring system (HEMS). Pecan Street completed the installation of HEMS in 750 homes and 25 commercial properties. The program provided incentives to increase the installed base of roof-top solar photovoltaic (PV) systems, plug-in electric vehicles with Level 2 charging, and smart appliances. Over 200 participants within a one square mile area took advantage of Austin Energy and Pecan Street’s joint PV incentive program and installed roof-top PV as part of this project. Of these homes, 69 purchased or leased an electric vehicle through Pecan Street’s PV rebate program and received a Level 2 charger from Pecan Street. Pecan Street studied the impacts of these technologies along with a variety of consumer behavior interventions, including pricing models, real-time feedback on energy use, incentive programs, and messaging, as well as the corresponding impacts on Austin Energy’s distribution assets.The primary demonstration site was the Mueller community in Austin, Texas. The Mueller development, located less than three miles from the Texas State Capitol

  3. USER FRUSTRATION IN HIT INTERFACES: EXPLORING PAST HCI RESEARCH FOR A BETTER UNDERSTANDING OF CLINICIANS' EXPERIENCES.

    Science.gov (United States)

    Opoku-Boateng, Gloria A

    2015-01-01

    User frustration research has been one way of looking into clinicians' experience with health information technology use and interaction. In order to understand how clinician frustration with Health Information Technology (HIT) use occurs, there is the need to explore Human-Computer Interaction (HCI) literature that addresses both frustration and HIT use. In the past three decades, HCI frustration research has increased and expanded. Researchers have done a lot of work to understand emotions, end-user frustration and affect. This paper uses a historical literature review approach to review the origins of emotion and frustration research and explore the research question; Does HCI research on frustration provide insights on clinicians' frustration with HIT interfaces? From the literature review HCI research on emotion and frustration provides additional insights that can indeed help explain user frustration in HIT. Different approaches and HCI perspectives also help frame HIT user frustration research as well as inform HIT system design. The paper concludes with a suggested directions on how future design and research may take.

  4. Evaluation of impacts of trees on PM2.5 dispersion in urban streets

    Science.gov (United States)

    Jin, Sijia; Guo, Jiankang; Wheeler, Stephen; Kan, Liyan; Che, Shengquan

    2014-12-01

    Reducing airborne particulate matter (PM), especially PM2.5 (PM with aerodynamic diameters of 2.5 μm or less), in urban street canyons is critical to the health of central city population. Tree-planting in urban street canyons is a double-edged sword, providing landscape benefits while inevitably resulting in PM2.5 concentrating at street level, thus showing negative environmental effects. Thereby, it is necessary to quantify the impact of trees on PM2.5 dispersion and obtain the optimum structure of street trees for minimizing the PM2.5 concentration in street canyons. However, most of the previous findings in this field were derived from wind tunnel or numerical simulation rather than on-site measuring data. In this study, a seasonal investigation was performed in six typical street canyons in the residential area of central Shanghai, which has been suffering from haze pollution while having large numbers of green streets. We monitored and measured PM2.5 concentrations at five heights, structural parameters of street trees and weather. For tree-free street canyons, declining PM2.5 concentrations were found with increasing height. However, in presence of trees the reduction rate of PM2.5 concentrations was less pronounced, and for some cases, the concentrations even increased at the top of street canyons, indicating tree canopies are trapping PM2.5. To quantify the decrease of PM2.5 reduction rate, we developed the attenuation coefficient of PM2.5 (PMAC). The wind speed was significantly lower in street canyons with trees than in tree-free ones. A mixed-effects model indicated that canopy density (CD), leaf area index (LAI), rate of change of wind speed were the most significant predictors influencing PMAC. Further regression analysis showed that in order to balance both environmental and landscape benefits of green streets, the optimum range of CD and LAI was 50%-60% and 1.5-2.0 respectively. We concluded by suggesting an optimized tree-planting pattern and

  5. Beyond discourse and competence : Science and subjugated knowledge in street children studies

    NARCIS (Netherlands)

    Gigengack, Roy

    2014-01-01

    This article argues that street children studies (SCS) has reduced its central concept to a discursive construct, and the young street people themselves to capable 'agents'. One consequence is that street children are not recognized as distinct intergenerational groupings in society. The traditional

  6. Solar charge controller in solar street light

    OpenAIRE

    Dong, Haibo

    2014-01-01

    Recently, with the rapid development of scientific technology, the conventional energy cannot meet the requirement of human beings. People are looking for the utilization of renew energy. Solar en-ergy as a new clean energy has attract the eyes of people. The applications of solar energy are popular to human society. Solar street light is a good example. This thesis will focus on a deeper research of the popular and ubiquitous solar street light in China. However, solar charge controll...

  7. Informing the Selection of Screening Hit Series with in Silico Absorption, Distribution, Metabolism, Excretion, and Toxicity Profiles.

    Science.gov (United States)

    Sanders, John M; Beshore, Douglas C; Culberson, J Christopher; Fells, James I; Imbriglio, Jason E; Gunaydin, Hakan; Haidle, Andrew M; Labroli, Marc; Mattioni, Brian E; Sciammetta, Nunzio; Shipe, William D; Sheridan, Robert P; Suen, Linda M; Verras, Andreas; Walji, Abbas; Joshi, Elizabeth M; Bueters, Tjerk

    2017-08-24

    High-throughput screening (HTS) has enabled millions of compounds to be assessed for biological activity, but challenges remain in the prioritization of hit series. While biological, absorption, distribution, metabolism, excretion, and toxicity (ADMET), purity, and structural data are routinely used to select chemical matter for further follow-up, the scarcity of historical ADMET data for screening hits limits our understanding of early hit compounds. Herein, we describe a process that utilizes a battery of in-house quantitative structure-activity relationship (QSAR) models to generate in silico ADMET profiles for hit series to enable more complete characterizations of HTS chemical matter. These profiles allow teams to quickly assess hit series for desirable ADMET properties or suspected liabilities that may require significant optimization. Accordingly, these in silico data can direct ADMET experimentation and profoundly impact the progression of hit series. Several prospective examples are presented to substantiate the value of this approach.

  8. HIV knowledge and sexual risk behavior among street adolescents ...

    African Journals Online (AJOL)

    HIV knowledge and sexual risk behavior among street adolescents in rehabilitation centres in Kinshasa; DRC: gender differences. ... Background: Street children, common in Africa, are increasingly vulnerable to alcohol and drugs of abuse and lack access to both healthcare and knowledge about HIV and AIDS. Hence, this ...

  9. 77 FR 67689 - Fidelity Aberdeen Street Trust, et al.;

    Science.gov (United States)

    2012-11-13

    ...] Fidelity Aberdeen Street Trust, et al.; Notice of Application November 6, 2012. AGENCY: Securities and... arrangements (``Prior Order'').\\1\\ \\1\\ Colchester Street Trust, et al., Investment Company Act Release Nos... Trust, et al., Investment Company Act Release Nos. 23787 (Apr. 15, 1999) (notice) and 23831 (May 11...

  10. HIT or miss: the application of health care information technology to managing uncertainty in clinical decision making.

    Science.gov (United States)

    Kazandjian, Vahé A; Lipitz-Snyderman, Allison

    2011-12-01

    To discuss the usefulness of health care information technology (HIT) in assisting care providers minimize uncertainty while simultaneously increasing efficiency of the care provided. An ongoing study of HIT, performance measurement (clinical and production efficiency) and their implications to the payment for care represents the design of this study. Since 2006, all Maryland hospitals have embarked on a multi-faceted study of performance measures and HIT adoption surveys, which will shape the health care payment model in Maryland, the last of the all-payor states, in 2011. This paper focuses on the HIT component of the Maryland care payment initiative. While the payment model is still under review and discussion, 'appropriateness' of care has been discussed as an important dimension of measurement. Within this dimension, the 'uncertainty' concept has been identified as associated with variation in care practices. Hence, the methods of this paper define how HIT can assist care providers in addressing the concept of uncertainty, and then provides findings from the first HIT survey in Maryland to infer the readiness of Maryland hospital in addressing uncertainty of care in part through the use of HIT. Maryland hospitals show noteworthy variation in their adoption and use of HIT. While computerized, electronic patient records are not commonly used among and across Maryland hospitals, many of the uses of HIT internally in each hospital could significantly assist in better communication about better practices to minimize uncertainty of care and enhance the efficiency of its production. © 2010 Blackwell Publishing Ltd.

  11. Hit Dexter: A Machine-Learning Model for the Prediction of Frequent Hitters.

    Science.gov (United States)

    Stork, Conrad; Wagner, Johannes; Friedrich, Nils-Ole; de Bruyn Kops, Christina; Šícho, Martin; Kirchmair, Johannes

    2018-03-20

    False-positive assay readouts caused by badly behaving compounds-frequent hitters, pan-assay interference compounds (PAINS), aggregators, and others-continue to pose a major challenge to experimental screening. There are only a few in silico methods that allow the prediction of such problematic compounds. We report the development of Hit Dexter, two extremely randomized trees classifiers for the prediction of compounds likely to trigger positive assay readouts either by true promiscuity or by assay interference. The models were trained on a well-prepared dataset extracted from the PubChem Bioassay database, consisting of approximately 311 000 compounds tested for activity on at least 50 proteins. Hit Dexter reached MCC and AUC values of up to 0.67 and 0.96 on an independent test set, respectively. The models are expected to be of high value, in particular to medicinal chemists and biochemists who can use Hit Dexter to identify compounds for which extra caution should be exercised with positive assay readouts. Hit Dexter is available as a free web service at http://hitdexter.zbh. uni-hamburg.de. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. A Numerical Simulation of Traffic-Related Air Pollution Exposures in Urban Street Canyons

    Science.gov (United States)

    Liu, J.; Fu, X.; Tao, S.

    2016-12-01

    Urban street canyons are usually associated with intensive vehicle emissions. However, the high buildings successively along both sides of a street block the dispersion of traffic-generated air pollutants, which enhances human exposure and adversely affects human health. In this study, an urban scale traffic pollution dispersion model is developed with the consideration of street distribution, canyon geometry, background meteorology, traffic assignment, traffic emissions and air pollutant dispersion. Vehicle exhausts generated from traffic flows will first disperse inside a street canyon along the micro-scale wind field (generated by computational fluid dynamics (CFD) model) and then leave the street canyon and further disperse over the urban area. On the basis of this model, the effects of canyon geometry on the distribution of NOx and CO from traffic emissions were studied over the center of Beijing, China. We found that an increase of building height along the streets leads to higher pollution levels inside streets and lower pollution levels outside, resulting in higher domain-averaged concentrations over the area. In addition, street canyons with equal (or highly uneven) building heights on two sides of a street tend to lower the urban-scale air pollution concentrations at pedestrian level. Our results indicate that canyon geometry strongly influences human exposure to traffic pollutants in the populated urban area. Carefully planning street layout and canyon geometry in consideration of traffic demand as well as local weather pattern may significantly reduce the chances of unhealthy air being inhaled by urban residents.

  13. Beyond discourse and competence: Science and subjugated knowledge in street children studies

    NARCIS (Netherlands)

    Gigengack, R.A.

    2014-01-01

    This article argues that street children studies (SCS) has reduced its central concept to a discursive construct, and the young street people themselves to capable ‘agents’. One consequence is that street children are not recognized as distinct intergenerational groupings in society. The traditional

  14. HitRECord: Cultura remix y copyright. Una experiencia en primera persona en el interior de la Compañía de Producción hitRECord.

    OpenAIRE

    Sabater Planelles, Pablo

    2016-01-01

    El Proyecto que hemos desarrollado, mezcla investigación y experiencia en primera persona entorno a dos temas principales con la finalidad de abordarlos, experimentarlos y comprenderlos de la mejor manera en el contexto actual. Mantienen una estrecha confrontación entre ellos y gran relación con la comunidad online hitRECord. Éstos son el copyright y la cultura remix. HitRECord es una plataforma online impulsada en el 2010 por el actor y artista Joseph Gordon-Levitt, convertida en una ...

  15. Development of pulsation technique for single ion hit system

    Energy Technology Data Exchange (ETDEWEB)

    Sakai, Takuro; Hamano, Tsuyoshi; Hirao, Toshio; Kamiya, Tomihiro [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment

    1996-12-01

    When a high energy heavy ion enters into a substance, high density of ionization and excitement occurrs along its flying trace. Especially, when such an ion enters into a semiconductor cell, a bit inversion called single event is occurred or a phenomenon destroyed element itself on case of the worst is formed. The present semiconductor cell is made in a size of some micron square, as different from its accumulated degree. In order to analyze the single event phenomenon formed by entering ion into such fine region in detail, a technique possible enter heavy ion beam with space resolution under 1 micron to each sample is necessary. In order to develop this technique, a static type high speed beam switch for control of entering a beam into a sample and a single ion detector for detecting entrance of ion into the sample were installed to heavy ion microbeam forming apparatus. The single ion hit system in Takasaki Radiation Chemistry Research Establishment, JAERI succeeded in detection and control technique of the single ion and control of noise due to pulsization and finished development of basic technique of the single ion hit, since now. After today, it is planned to hit actually the single ion onto the sample and evaluate its accuracy. (G.K.)

  16. Biomarkers for IgA nephropathy on the basis of multi-hit pathogenesis.

    Science.gov (United States)

    Suzuki, Hitoshi

    2018-05-08

    IgA nephropathy (IgAN) is the most prevalent glomerular disease worldwide and is associated with a poor prognosis. Development of curative treatment strategies and approaches for early diagnosis is necessary. Renal biopsy is the gold standard for the diagnosis and assessment of disease activity. However, reliable biomarkers are needed for the noninvasive diagnosis of this disease and to more fully delineate the risk of progression. With regard to the pathogenesis of IgAN, the multi-hit hypothesis, including production of galactose-deficient IgA1 (Gd-IgA1; Hit 1), IgG or IgA autoantibodies that recognize Gd-IgA1 (Hit 2), and their subsequent immune complexes formation (Hit 3) and glomerular deposition (Hit 4), has been widely supported by many studies. Although the prognostic values of several biomarkers have been discussed, we recently developed a highly sensitive and specific diagnostic method by measuring serum levels of Gd-IgA1 and Gd-IgA1-containing immune complexes. In addition, urinary Gd-IgA1 may represent a disease-specific biomarker for IgAN. We also confirmed that there is a significant correlation between serum levels of these effector molecules and disease activity, suggesting that each can be considered a practical surrogate marker of therapeutic response. Thus, these disease-oriented specific serum and urine biomarkers may be useful for screening of potential IgAN with isolated hematuria, earlier diagnosis, disease activity, and eventually, response to treatment. In this review, we discuss these concepts, with a focus on potential clinical applications of these biomarkers.

  17. [Who Hits the Mark? A Comparative Study of the Free Geocoding Services of Google and OpenStreetMap].

    Science.gov (United States)

    Lemke, D; Mattauch, V; Heidinger, O; Hense, H W

    2015-09-01

    Geocoding, the process of converting textual information (addresses) into geographic coordinates is increasingly used in public health/epidemiological research and practice. To date, little attention has been paid to geocoding quality and its impact on different types of spatially-related health studies. The primary aim of this study was to compare 2 freely available geocoding services (Google and OpenStreetMap) with regard to matching rate (percentage of address records capable of being geocoded) and positional accuracy (distance between geocodes and the ground truth locations). Residential addresses were geocoded by the NRW state office for information and technology and were considered as reference data (gold standard). The gold standard included the coordinates, the quality of the addresses (4 categories), and a binary urbanity indicator based on the CORINE land cover data. 2 500 addresses were randomly sampled after stratification for address quality and urbanity indicator (approximately 20 000 addresses). These address samples were geocoded using the geocoding services from Google and OSM. In general, both geocoding services showed a decrease in the matching rate with decreasing address quality and urbanity. Google showed consistently a higher completeness than OSM (>93 vs. >82%). Also, the cartographic confounding between urban and rural regions was less distinct with Google's geocoding API. Regarding the positional accuracy of the geo-coordinates, Google also showed the smallest deviations from the reference coordinates, with a median of Google that nearly 95% and for OSM 50% of the addresses were geocoded within Google is superior to OSM regarding completeness and positional accuracy of the geocoded addresses. On the other hand, Google has several restrictions, such as the limitation of the requests to 2 500 addresses per 24 h and the presentation of the results exclusively on Google Maps, which may complicate the use for scientific purposes.

  18. Dual hit lipopolysaccharide & oleic acid combination induced rat model of acute lung injury/acute respiratory distress syndrome

    Directory of Open Access Journals (Sweden)

    T N Hagawane

    2016-01-01

    Results: It was noted that the respiratory rate, and tumour necrosis factor-α (TNF-α levels were significantly higher at 4 h in the dual hit group as compared to LPS, OA and control groups. Interleukin-6 (IL-6 levels were significantly higher in the dual hit group as compared to LPS at 8 and 24 h, OA at 8 h and control (at all time intervals group. IL-1β levels were significantly higher in LPS and dual hit groups at all time intervals, but not in OA and control groups. The injury induced in dual hit group was earlier and more sustained as compared to LPS and OA alone. Interpretation & conclusions: The lung pathology and changes in respiration functions produced by the dual hit model were closer to the diagnostic criteria of ALI/ARDS in terms of clinical manifestations and pulmonary injury and the injury persisted longer as compared to LPS and OA single hit model. Therefore, the ARDS model produced by the dual hit method was closer to the diagnostic criteria of ARDS in terms of clinical manifestations and pulmonary injury.

  19. Hit-size effectiveness theory applied to high doses of low LET radiation for pink mutations in Tradescantia

    International Nuclear Information System (INIS)

    Varma, M.N.; Bond, V.P.; Matthews, G.

    1985-01-01

    A hit-size effectiveness function which represents the probability of inducing a pink mutation in Tradescantia as a function of lineal energy density has been obtained (1) using observed pink mutation data for seven different radiation qualities and their respective single event microdosimetric spectra. In obtaining this function only the linear portions of dose-response curves were used. A significant improvement of the concepts embodied in the proposed hit-size effectiveness theory would be the demonstration of its applicability at high doses (where multiple hits are produced) and high dose rates (at which no significant biological repair takes place). In this article details are given on preliminary calculations of the pink mutation frequency in Tradescantia at 1, 5, 10, 20, and 60 rads for 250 kVp x rays, using the multi-hit spectra and the hit-size effectiveness function obtained on the basis of single hit microdosimetric spectra as outline in (1). A comparison of the calculated and observed pink mutation frequencies indicate excellent agreement and suggests the possibility of obtaining the hit-size effectiveness function from high dose biological-effect data obtained using low-LET radiations. 6 refs., 3 figs., 3 tabs

  20. Gorlin syndrome with an ovarian leiomyoma associated with a PTCH1 second hit.

    Science.gov (United States)

    Akizawa, Yoshika; Miyashita, Toshiyuki; Sasaki, Ryo; Nagata, Reiko; Aoki, Ryoko; Ishitani, Ken; Nagashima, Yoji; Matsui, Hideo; Saito, Kayoko

    2016-04-01

    We describe a Gorlin syndrome (GS) case with two different second hit mutations of PTCH1, one in a keratocystic odontogenic tumor (KCOT) and the other in an ovarian leiomyoma. GS is a rare genetic condition manifesting as multiple basal cell nevi associated with other features such as medulloblastomas, skeletal abnormalities, and ovarian fibromas. A 21-year-old Japanese woman with a history of two KCOTs was diagnosed with GS according to clinical criteria. A PTCH1 mutation, c.1427del T, was detected in peripheral blood. A novel PTCH1 mutation, c.264_265insAATA, had been found in the maxillary KCOT as a second hit mutation. More recently, the ovarian tumor was detected during a gynecological examination. Laparoscopic adnexectomy was performed, and the pathological diagnosis of the ovarian tumor was leiomyoma. Interestingly, another novel mutation, loss of heterozygosity spanning from 9q22.32 to 9q31.2, including PTCH1 and 89 other genes, was detected in this ovarian tumor, providing evidence of a second hit mutation. This is the first report describing a GS-associated ovarian tumor carrying a second hit in the PTCH1 region. We anticipate that accumulation of more cases will clarify the importance of second hit mutations in ovarian tumor formation in GS. © 2016 Wiley Periodicals, Inc.

  1. An Analysis of the Street-Children Phenomenon in the City of Isfahan

    OpenAIRE

    Seyed Alireza Afshani; Abbas Askari-Nodoushan; Mohammad Heydari; Mohammad Noorian Najafabadi

    2013-01-01

    Introduction   In nearly all big cities around the world, the phenomenon of street children is one of the contemporary social issues. During past several decades, there is an increase in the volume of street children phenomenon around the world. The rising number of street children has many pathological and consequential negative impacts for children, youth, families, and the society at the whole . According to 2000 UN report, the number of street children is estimated between 100 to140 milli...

  2. An investigation on the effect of street morphology to ambient air quality using six real-world cases

    Science.gov (United States)

    Shen, Jialei; Gao, Zhi; Ding, Wowo; Yu, Ying

    2017-09-01

    Street canyons are vulnerable to air pollution mainly caused by vehicle emissions, which are therefore closely related to pedestrians' health. Previous studies have showed that air quality in street canyons is associated with street morphology, though the majority of them have focused on idealized street models. This paper attempts to investigate the relationship of street morphology to air quality for 6 irregular real-world cases selected from America, Europe, and China, i.e. Manhattan, Paris, Barcelona, Berlin, London and Nanjing. Each street is analyzed as a set of slices to propose a couple of morphology indices for quantitatively assessing the actual street morphology. Pollutant transport rate of mean flows and turbulent diffusion, net escape velocity and age of air are obtained from computational fluid dynamics (CFD) simulations to assess the ventilations and pollutant dispersion within street canyons with a parallel approaching wind. The results show that the street morphology characteristics, including the street width, lateral openings and intersections, are closely related to the air flows in street canyons. The air quality improves with a decreasing aspect ratio of central street owing to a larger vertical exchange through the street roof, which suggests an open central street is of better air quality. The lateral openings and intersections of streets have important effects on the air flows in street canyons, and the effects are particularly pronounced when the street widths are similar. The street continuity ratio indicates street continuity. It relates to the openings and the symmetry of a street and impacts on the air flows and pollutant dispersion through the lateral openings of the central street. The street spatial closure ratio is determined by the street continuity ratio and the aspect ratio of the central street. When the aspect ratio of central street is not excessively high, higher values of street continuity ratio and spatial closure ratio

  3. Neglected populations: safeguarding the health of street-involved children in Ghana.

    Science.gov (United States)

    Osei-Twum, Jo-Ann; Wasan, Kishor M

    2012-10-01

    Ensuring the health of street-involved children is a growing public health challenge. These children are vulnerable, neglected, and rarely a priority for basic service providers and governments. Sizable populations of street-involved children are present in major urban areas worldwide and current trends in urbanization suggest these populations will grow in the coming years. Although migration offers employment and training opportunities, the health and wellbeing of children is negatively impacted by their interactions with the streets. However, systemic barriers may also prevent these children from achieving an adequate health status. The situation of street-involved children in Ghana, West Africa will be discussed. Copyright © 2012 Wiley Periodicals, Inc.

  4. Importance-satisfaction analysis of street food sanitation and choice factor in Korea and Taiwan

    OpenAIRE

    Joo, Nami; Park, Sanghyun; Lee, Bohee; Yoon, Jiyoung

    2015-01-01

    BACKGROUND/OBJECTIVES The present study investigated Korean and Taiwan adults on the importance of and the satisfaction with street food sanitation and street food choice factor, in order to present management and improvement measures for street foods. SUBJECTS/METHODS The present study conducted a survey on 400 randomly chosen adults (200 Korean, 200 Taiwanese). General characteristics, eating habits, street food intake frequency, and preference by type of street food of respondents were che...

  5. Double-hit lymphomas constitute a highly aggressive subgroup in diffuse large B-cell lymphomas in the era of rituximab.

    Science.gov (United States)

    Kobayashi, Tsutomu; Tsutsumi, Yasuhiko; Sakamoto, Natsumi; Nagoshi, Hisao; Yamamoto-Sugitani, Mio; Shimura, Yuji; Mizutani, Shinsuke; Matsumoto, Yosuke; Nishida, Kazuhiro; Horiike, Shigeo; Asano, Naoko; Nakamura, Shigeo; Kuroda, Junya; Taniwaki, Masafumi

    2012-11-01

    The incorporation of rituximab in immunochemotherapy has improved treatment outcomes for diffuse large B-cell lymphoma, but the prognosis for some diffuse large B-cell lymphomas remains dismal. Identification of adverse prognostic subgroups is essential for the choice of appropriate therapeutic strategy. We retrospectively investigated the impact of so-called 'double-hit' cytogenetic abnormalities, i.e. cytogenetic abnormalities involving c-MYC co-existing with other poor prognostic cytogenetic abnormalities involving BCL2, BCL6 or BACH2, on treatment outcomes for 93 consecutive diffuse large B-cell lymphoma patients. According to the revised international prognostic index, no patients were cytogenetically diagnosed with double-hit lymphomas in the 'very good' risk group or in the 'good' risk group, while 5 of 33 patients had double-hit lymphomas in the 'poor' risk group. All the double-hit lymphoma patients possessed both nodal and extranodal involvement. The overall complete response rate was 89.3%, overall survival 87.1% and progression-free survival 75.8% over 2 years (median observation period: 644 days). The complete response rates were 93.2% for the non-double-hit lymphoma patients and 40.0% for the double-hit lymphoma patients. Significantly longer progression-free survival and overall survival were observed for the 'very good' and the 'good' risk patients than for the 'poor' risk patients. Moreover, the progression-free survival of double-hit lymphoma was significantly shorter than that of the non-double-hit lymphoma 'poor' risk patients (P = 0.016). In addition, the overall survival of the double-hit lymphoma patients also tended to be shorter than that of the non-double-hit lymphoma 'poor' risk group. The diagnosis of double-hit lymphoma can help discriminate a subgroup of highly aggressive diffuse large B-cell lymphomas and indicate the need for the development of novel therapeutic strategies for double-hit lymphoma.

  6. PF4-HIT antibody (KKO) complexes activate broad innate immune and inflammatory responses.

    Science.gov (United States)

    Haile, Lydia A; Rao, Roshni; Polumuri, Swamy K; Arepally, Gowthami M; Keire, David A; Verthelyi, Daniela; Sommers, Cynthia D

    2017-11-01

    Heparin-induced thrombocytopenia (HIT) is an immune-mediated complication of heparin anticoagulation therapy resulting in thrombocytopenia frequently accompanied by thrombosis. Current evidence suggests that HIT is associated with antibodies developed in response to multi-molecular complexes formed by platelet factor 4 (PF4) bound to heparin or cell surface glycosaminoglycans. These antibody complexes activate platelets and monocytes typically through FcγRIIA receptors increasing the production of PF4, inflammatory mediators, tissue factor and thrombin. The influence of underlying events in HIT including complex-induced pro-inflammatory cell activation and structural determinants leading to local inflammatory responses are not fully understood. The stoichiometry and complex component requirements were determined by incubating fresh peripheral blood mononuclear cells (PBMC) with different concentrations of unfractionated heparin (H), low molecular weight heparin (LMWH), PF4- and anti-PF4-H complex antibodies (KKO). Cytokine mRNA or protein were measured by qRT-PCR or Meso Scale Discovery technology, respectively. Gene expression profile analysis for 594 genes was performed using Nanostring technology and analyzed using Ingenuity Pathway Analysis software. The data show that antibodies magnify immune responses induced in PBMCs by PF4 alone or in complex with heparin or LMWH. We propose that following induction of HIT antibodies by heparin-PF4 complexes, binding of the antibodies to PF4 is sufficient to induce a local pro-inflammatory response which may play a role in the progression of HIT. In vitro assays using PBMCs may be useful in characterizing local inflammatory and innate immune responses induced by HIT antibodies in the presence of PF4 and different sources of heparins. The findings and conclusions in this article are solely the responsibility of the authors and are not being formally disseminated by the Food and Drug Administration. Thus, they should not be

  7. Effect of stable stratification on dispersion within urban street canyons: A large-eddy simulation

    Science.gov (United States)

    Li, Xian-Xiang; Britter, Rex; Norford, Leslie K.

    2016-11-01

    This study employs a validated large-eddy simulation (LES) code with high tempo-spatial resolution to investigate the effect of a stably stratified roughness sublayer (RSL) on scalar transport within an urban street canyon. The major effect of stable stratification on the flow and turbulence inside the street canyon is that the flow slows down in both streamwise and vertical directions, a stagnant area near the street level emerges, and the vertical transport of momentum is weakened. Consequently, the transfer of heat between the street canyon and overlying atmosphere also gets weaker. The pollutant emitted from the street level 'pools' within the lower street canyon, and more pollutant accumulates within the street canyon with increasing stability. Under stable stratification, the dominant mechanism for pollutant transport within the street canyon has changed from ejections (flow carries high-concentration pollutant upward) to unorganized motions (flow carries high-concentration pollutant downward), which is responsible for the much lower dispersion efficiency under stable stratifications.

  8. The Initiation of Homeless Youth into the Street Economy

    Science.gov (United States)

    Gwadz, Marya Viorst; Gostnell, Karla; Smolenski, Carol; Willis, Brian; Nish, David; Nolan, Theresa C.; Tharaken, Maya; Ritchie, Amanda S.

    2009-01-01

    Homeless youth (HY) who lack employment in the formal economy typically turn to the street economy (e.g., prostitution, drug selling) for survival. Guided by the theory of social control, the present paper explores factors influencing HY's initiation into the street economy. Eighty HY (ages 15-23) were recruited from four community-based…

  9. Hygiene practices among street food vendors in Tamale Metropolis ...

    African Journals Online (AJOL)

    The study noted that street food business in the Tamale Metropolis was women dominated (76%). Majority of vendors (78%) were aged 20-39 years. Public toilets (pit latrines) were accessible to all vending sites. Though high number of street food vendors had some form of formal education (66%) and knowledge of food ...

  10. Measurements and Simulations on the Mechanisms of Efficiency Losses in HIT Solar Cells

    Directory of Open Access Journals (Sweden)

    Silvio Pierro

    2015-01-01

    Full Text Available We study the electrical and the optical behavior of HIT solar cell by means of measurements and optoelectrical simulations by TCAD simulations. We compare the HIT solar cell with a conventional crystalline silicon solar cell to identify the strengths and weaknesses of the HIT technology. Results highlight different mechanisms of electrical and optical efficiency losses caused by the presence of the amorphous silicon layer. The higher resistivity of the a-Si layers implies a smaller distance between the metal lines that causes a higher shadowing. The worst optical coupling between the amorphous silicon and the antireflective coating implies a slight increase of reflectivity around the 600 nm wavelength.

  11. Self-Localization at Street Intersections.

    Science.gov (United States)

    Fusco, Giovanni; Shen, Huiying; Coughlan, James M

    2014-05-01

    There is growing interest among smartphone users in the ability to determine their precise location in their environment for a variety of applications related to wayfinding, travel and shopping. While GPS provides valuable self-localization estimates, its accuracy is limited to approximately 10 meters in most urban locations. This paper focuses on the self-localization needs of blind or visually impaired travelers, who are faced with the challenge of negotiating street intersections. These travelers need more precise self-localization to help them align themselves properly to crosswalks, signal lights and other features such as walk light pushbuttons. We demonstrate a novel computer vision-based localization approach that is tailored to the street intersection domain. Unlike most work on computer vision-based localization techniques, which typically assume the presence of detailed, high-quality 3D models of urban environments, our technique harnesses the availability of simple, ubiquitous satellite imagery (e.g., Google Maps) to create simple maps of each intersection. Not only does this technique scale naturally to the great majority of street intersections in urban areas, but it has the added advantage of incorporating the specific metric information that blind or visually impaired travelers need, namely, the locations of intersection features such as crosswalks. Key to our approach is the integration of IMU (inertial measurement unit) information with geometric information obtained from image panorama stitchings. Finally, we evaluate the localization performance of our algorithm on a dataset of intersection panoramas, demonstrating the feasibility of our approach.

  12. Lessons learnt from the Wenchuan earthquake: performance evaluation of treatment of critical injuries in hardest-hit areas.

    Science.gov (United States)

    Jiang, Jie; Li, Youping; Huang, Xiaolin; Li, Bing; Su, Lin; Zhong, Dake; Shi, Chenghu; Li, Mingxu; Shan, Juan; Chen, Yin

    2012-08-01

    Critical injury treatment in the hardest-hit areas after a great earthquake was retrospectively analyzed to determine how best to reduce mortality and disability and increase the rehabilitation rate through postquake medical relief. Retrospective analysis, primary sources, and secondary sources were comprehensively retrieved and analyzed. According to incomplete data, 30,620 injured were rescued by themselves among the hardest-hit areas in the 72 hours immediately following the earthquake. Critically injured patients accounted for 22% of total inpatients. Mortality rates declined with greater distance from the epicenter: rates were 12.21% for municipal healthcare centers in the hardest-hit areas, 4.50% for municipal medical units in peripheral quake-hit areas, 2.50% for provincial medical units in peripheral quake-hit areas, and 2.17% for Ministry of Health-affiliated hospitals in peripheral quake-hit areas. The number of injured with fractures on body, limbs or unknown-parts, severe conditions as well as other kinds of non-traumatic diseases received in second-line hospitals was much more than those treated in first-line hospitals with more severe injuries. Among 10,373 injured in stable condition transferred to third-line hospitals, 99.07% were discharged from hospitals within four months, while the mortality rate was 0.017%. The medical relief model of "supervising body helping subordinate unit, severely stricken areas assisting hardest-hit areas, least-hit areas supporting both hardest-hit and severely stricken areas, and self help and mutual assistance applied between hardest-hit areas" was roughly established for injured from severely stricken areas after the Wenchuan Earthquake. The "four-centralization" treatment principle, which referred to concentrating patients, experts, resources and treatment for those injured in critical condition effectively reduced the mortality from 15.06% to 2.9%. Timely, scientific, and standard on-site triage and postmedical

  13. The Holistic Integrity Test (HIT - quantified resilience analysis

    Directory of Open Access Journals (Sweden)

    Dobson Mike

    2016-01-01

    Full Text Available The Holistic Integrity Test (HIT - Quantified Resilience Analysis. Rising sea levels and wider climate change mean we face an increasing risk from flooding and other natural hazards. Tough economic times make it difficult to economically justify or afford the desired level of engineered risk reduction. Add to this significant uncertainty from a range of future predictions, constantly updated with new science. We therefore need to understand not just how to reduce the risk, but what could happen should above design standard events occur. In flood terms this includes not only the direct impacts (damage and loss of life, but the wider cascade impacts to infrastructure systems and the longer term impacts on the economy and society. However, understanding the “what if” is only the first part of the equation; a range of improvement measures to mitigate such effects need to be identified and implemented. These measures should consider reducing the risk, lessening the consequences, aiding the response, and speeding up the recovery. However, they need to be objectively assessed through quantitative analysis, which underpins them technically and economically. Without such analysis, it cannot be predicted how measures will perform if the extreme events occur. It is also vital to consider all possible hazards as measures for one hazard may hinder the response to another. The Holistic Integrity Test (HIT, uses quantitative system analysis and “HITs” the site, its infrastructure, contained dangers and wider regional system to determine how it copes with a range of severe shock events, Before, During and After the event, whilst also accounting for uncertainty (as illustrated in figure 1. First explained at the TINCE 2014 Nuclear Conference in Paris, it was explained in terms of a Nuclear Facility needing to analyse the site in response to post Fukushima needs; the hit is however universally applicable. The HIT has three key risk reduction goals: The

  14. Temporal, spatial and social patterens of self-organization within street sport

    DEFF Research Database (Denmark)

    Sand, Anne-Lene

    Due to an increased urbanization and digitalization self-organized practices are becoming a central way of doing sports among contemporary young people and adults in urban contexts. The aim of this presentation is to contribute with knowledge about what it means to be self-organized within street...... young people can re-define urban space themselves (Skelton and Valentine 2007). During a multi-sited fieldwork (Marcus 1995) I followed people in Denmark that value to be able to improvise in the way they organize their own street-sport practices through temporal, spatial and social practices. Street...... among young people and adults, in order to redefine and reconstruct future leisure organizations (Rojek 1995) and understand contemporary forms of street sport....

  15. The propagation of sound in narrow street canyons

    Science.gov (United States)

    Iu, K. K.; Li, K. M.

    2002-08-01

    This paper addresses an important problem of predicting sound propagation in narrow street canyons with width less than 10 m, which are commonly found in a built-up urban district. Major noise sources are, for example, air conditioners installed on building facades and powered mechanical equipment for repair and construction work. Interference effects due to multiple reflections from building facades and ground surfaces are important contributions in these complex environments. Although the studies of sound transmission in urban areas can be traced back to as early as the 1960s, the resulting mathematical and numerical models are still unable to predict sound fields accurately in city streets. This is understandable because sound propagation in city streets involves many intriguing phenomena such as reflections and scattering at the building facades, diffusion effects due to recessions and protrusions of building surfaces, geometric spreading, and atmospheric absorption. This paper describes the development of a numerical model for the prediction of sound fields in city streets. To simplify the problem, a typical city street is represented by two parallel reflecting walls and a flat impedance ground. The numerical model is based on a simple ray theory that takes account of multiple reflections from the building facades. The sound fields due to the point source and its images are summed coherently such that mutual interference effects between contributing rays can be included in the analysis. Indoor experiments are conducted in an anechoic chamber. Experimental data are compared with theoretical predictions to establish the validity and usefulness of this simple model. Outdoor experimental measurements have also been conducted to further validate the model. copyright 2002 Acoustical Society of America.

  16. Anticipating mismatches of HIT investments: Developing a viability-fit model for e-health services.

    Science.gov (United States)

    Mettler, Tobias

    2016-01-01

    Albeit massive investments in the recent years, the impact of health information technology (HIT) has been controversial and strongly disputed by both research and practice. While many studies are concerned with the development of new or the refinement of existing measurement models for assessing the impact of HIT adoption (ex post), this study presents an initial attempt to better understand the factors affecting viability and fit of HIT and thereby underscores the importance of also having instruments for managing expectations (ex ante). We extend prior research by undertaking a more granular investigation into the theoretical assumptions of viability and fit constructs. In doing so, we use a mixed-methods approach, conducting qualitative focus group discussions and a quantitative field study to improve and validate a viability-fit measurement instrument. Our findings suggest two issues for research and practice. First, the results indicate that different stakeholders perceive HIT viability and fit of the same e-health services very unequally. Second, the analysis also demonstrates that there can be a great discrepancy between the organizational viability and individual fit of a particular e-health service. The findings of this study have a number of important implications such as for health policy making, HIT portfolios, and stakeholder communication. Copyright © 2015. Published by Elsevier Ireland Ltd.

  17. [Street food among children: a study in north Tunisia].

    Science.gov (United States)

    Neffati, Larbi; Ridha, Hamza; Kolsteren, Patrick; Hilderbrand, Katherine

    2004-01-01

    As urbanization increases in Tunisia, eating meals outside the home is becoming more frequent. Children are prime consumers for the fast food sold in the streets. Neither their nor their parents' attitude towards street food is well documented as yet. This study was conducted in the city of Bizerte in February 1998. Its aim was to gather information about street food and parents' and children's attitudes towards it to help organize educational sessions with the children, parents, teachers, and vendors. The study interviewed 421 primary school children, ranging in age from 6 to 15 years (mean age: 10 years), from 24 schools. Half received pocket money, a percentage that did not differ by sex. Three quarters of the children used more than 75% of their pocket money to buy street food. The items bought most frequently were candy (27.2%), sandwiches (23.9%), pastries (23.9%), sunflower seeds and peanuts (21%), and either pizza, chocolate, or cheese (20.3%); the largest proportion of money was spent on sandwiches. In more than half the cases (55.7% of the children), the main motivation for buying street food was either to replace or fill out a meal at home, with sandwiches or pastries. The parents' monthly income did not influence the children's purchasing behavior, but the rhythm of receiving pocket money did. Most children were satisfied with the nutritional and hygienic quality of the food available, but their opinion of this quality as well as the reasons for buying the food and the prices spent on it differed considerably from that of their parents. This study highlights the important role of street foods in the daily diet of schoolchildren and the need for appropriate nutrition education in primary schools.

  18. What information do Karman streets offer to flow sensing?

    Energy Technology Data Exchange (ETDEWEB)

    Akanyeti, Otar; Venturelli, Roberto; Visentin, Francesco; Fiorini, Paolo [Department of Computer Science, University of Verona, 37134 Verona (Italy); Chambers, Lily; Megill, William M, E-mail: otarakanyeti@yahoo.com [Department of Mechanical Engineering, University of Bath, Bath BA2 7AY (United Kingdom)

    2011-09-15

    In this work, we focus on biomimetic lateral line sensing in Karman vortex streets. After generating a Karman street in a controlled environment, we examine the hydrodynamic images obtained with digital particle image velocimetry (DPIV). On the grounds that positioning in the flow and interaction with the vortices govern bio-inspired underwater locomotion, we inspect the fluid in the swimming robot frame of reference. We spatially subsample the flow field obtained using DPIV to emulate the local flow around the body. In particular, we look at various sensor configurations in order to reliably identify the vortex shedding frequency, wake wavelength and downstream flow speed. Moreover, we propose methods that differentiate between being in and out of the Karman street with >70% accuracy, distinguish right from left with respect to Karman vortex street centreline (>80%) and highlight when the sensor system enters the vortex formation zone (>75%). Finally, we present a method that estimates the relative position of a sensor array with respect to the vortex formation point within 15% error margin.

  19. Characteristic, Emotional, and Behavioral Problems of Street Adolescent in Bandung October–December 2012

    Directory of Open Access Journals (Sweden)

    Annisa Nurfitriani

    2015-06-01

    Full Text Available Background: Street adolescents were psychosocial problem that increased in number each year and was worsened by their low-moral subculture-value that could cause them more vulnerable in having emotional and behavioral problems. This study aims to describe the characteristics, emotional and behavioral problems of the street adolescent in Bandung. Methods: A descriptive study was carried out in October–December 2012. From 22 shelters in Bandung, two shelters (RPA GANK and Pesantren Kolong Nurul Hayat were selected and organized into 4 areas: Cihampelas, ‘Samsat’, Laswi Street and Kiaracondong. A hundred-seven street adolescents aged 11 to 16 years were participated in this study. They were divided into small groups and filled in the sociodemographic questionnaire and the Indonesian version of standardized Strength and Difficulty Questionnaires (SDQ. Only 100 questionnaires were filled in completely. Data were analyzed using frequency tabulation and bar chart Results: Sixty-five percent were boys, 53% were aged 11–13 years, and 53% were students, 76% related to more than one sibling, still lived with their families (81%, and had parents. Their parents had low educational background, had job, and implemented authoritative parenting pattern (41%. In becoming street adolescent, 63% were caused by their own motivation, 81% were children on street, and 55% had lived in the street more than 5 years. Approximately 27% of street adolescents were rated as abnormal on the total difficulty score. Conclusion: Street adolescent in Bandung still have emotional and behavioral problems, which mostly were boys, in the early adolescence stage, school student, had more than one sibling, permissive parenting pattern, and lived in the street for more than 5 years.

  20. Importance-satisfaction analysis of street food sanitation and choice factor in Korea and Taiwan.

    Science.gov (United States)

    Joo, Nami; Park, Sanghyun; Lee, Bohee; Yoon, Jiyoung

    2015-06-01

    The present study investigated Korean and Taiwan adults on the importance of and the satisfaction with street food sanitation and street food choice factor, in order to present management and improvement measures for street foods. The present study conducted a survey on 400 randomly chosen adults (200 Korean, 200 Taiwanese). General characteristics, eating habits, street food intake frequency, and preference by type of street food of respondents were checked. Respondents' importance and satisfaction of street food hygiene and selection attributes were also measured. In order to test for the difference between groups, χ(2)-test and t-test were performed. ISA was also performed to analyze importance and satisfaction. Results showed that the importance of sanitation was significantly higher than satisfaction on all items in both Korea and Taiwan, and the satisfaction with sanitation was higher in Taiwan than in Korea. According to ISA results with street food sanitation, satisfaction was low while importance was high in both Korea and Taiwan. In terms of street food choice factor, importance scores were significantly higher than satisfaction scores on all items. In addition, satisfaction scores on all items except 'taste' were significantly higher in Taiwan than in Korea. A manual on sanitation management of street foods should be developed to change the knowledge and attitude toward sanitation by putting into practice a regularly conducted education. Considering the popularity of street foods and its potential as a tourism resource to easily publicize our food culture, thorough management measures should be prepared on sanitation so that safe street food culture should be created.

  1. Effect of asymmetrical street canyons on pedestrian thermal comfort in warm-humid climate of Cuba

    Science.gov (United States)

    Rodríguez-Algeciras, José; Tablada, Abel; Matzarakis, Andreas

    2017-07-01

    Walkability and livability in cities can be enhanced by creating comfortable environments in the streets. The profile of an urban street canyon has a substantial impact on outdoor thermal conditions at pedestrian level. This paper deals with the effect of asymmetrical street canyon profiles, common in the historical centre of Camagüey, Cuba, on outdoor thermal comfort. Temporal-spatial analyses are conducted using the Heliodon2 and the RayMan model, which enable the generation of accurate predictions about solar radiation and thermal conditions of urban spaces, respectively. On these models, urban settings are represented by asymmetrical street canyons with five different height-to-width ratios and four street axis orientations (N-S, NE-SW, E-W, SE-NW). Results are evaluated for daytime hours across the street canyon, by means of the physiologically equivalent temperature (PET index) which allows the evaluation of the bioclimatic conditions of outdoor environments. Our findings revealed that high profiles (façades) located on the east-facing side of N-S streets, on the southeast-facing side of NE-SW streets, on the south-facing side of E-W street, and on the southwest-facing side of SE-NW streets, are recommended to reduce the total number of hours under thermal stress. E-W street canyons are the most thermally stressed ones, with extreme PET values around 36 °C. Deviating from this orientation ameliorates the heat stress with reductions of up to 4 h in summer. For all analysed E-W orientations, only about one fifth of the street can be comfortable, especially for high aspect ratios (H/W > 3). Optimal subzones in the street are next to the north side of the E-W street, northwest side of the NE-SW street, and southwest side of the SE-NW street. Besides, when the highest profile is located on the east side of N-S streets, then the subzone next to the east-facing façade is recommendable for pedestrians. The proposed urban guidelines enable urban planners to create

  2. Study of locations’characteristics for stabilization of street vendors in Surakarta City

    Science.gov (United States)

    Rahayu, M. J.; Buchori, I.; Widjajanti, R.

    2018-01-01

    Street vendors are usually centered around particular areas where they have made adaptations based on their activities, instead of scattered all over the city. These locations tend to be close to street vendors’ primary activities and consumers, occupy the public lands, and are productive and accessible. The Municipality of Surakarta has managed the street vendors in the form of stabilization and relocation. In Surakarta, there are 24 areas used for stabilization of street vendors varying in characteristics and quantities. This study uses a spatial analysis aiming to explain the characteristics of locations used for stabilization of street vendors and to identify their physical condition and arrangement. Furthermore, all of the research results will be used as the criteria in choosing the new locations that are suitable for the street vendors’ characteristics and consumers’ preference. The results show that the locations are on the roadsides of the neighborhood, local, and secondary collector roads. The traffic conditions in the stabilization areas are ranging from the very busy until relatively busy level since they are close to activities for trade, education, recreation, offices, and settlements.

  3. The prognosis of MYC translocation positive diffuse large B-cell lymphoma depends on the second hit.

    Science.gov (United States)

    Clipson, Alexandra; Barrans, Sharon; Zeng, Naiyan; Crouch, Simon; Grigoropoulos, Nicholas F; Liu, Hongxiang; Kocialkowski, Sylvia; Wang, Ming; Huang, Yuanxue; Worrillow, Lisa; Goodlad, John; Buxton, Jenny; Neat, Michael; Fields, Paul; Wilkins, Bridget; Grant, John W; Wright, Penny; Ei-Daly, Hesham; Follows, George A; Roman, Eve; Watkins, A James; Johnson, Peter W M; Jack, Andrew; Du, Ming-Qing

    2015-07-01

    A proportion of MYC translocation positive diffuse large B-cell lymphomas (DLBCL) harbour a BCL2 and/or BCL6 translocation, known as double-hit DLBCL, and are clinically aggressive. It is unknown whether there are other genetic abnormalities that cooperate with MYC translocation and form double-hit DLBCL, and whether there is a difference in clinical outcome between the double-hit DLBCL and those with an isolated MYC translocation. We investigated TP53 gene mutations along with BCL2 and BCL6 translocations in a total of 234 cases of DLBCL, including 81 with MYC translocation. TP53 mutations were investigated by PCR and sequencing, while BCL2 and BCL6 translocation was studied by interphase fluorescence in situ hybridization. The majority of MYC translocation positive DLBCLs (60/81 = 74%) had at least one additional genetic hit. In MYC translocation positive DLBCL treated by R-CHOP ( n  = 67), TP53 mutation and BCL2, but not BCL6 translocation had an adverse effect on patient overall survival. In comparison with DLBCL with an isolated MYC translocation, cases with MYC/TP53 double-hits had the worst overall survival, followed by those with MYC/BCL2 double-hits. In MYC translocation negative DLBCL treated by R-CHOP ( n  = 101), TP53 mutation, BCL2 and BCL6 translocation had no impact on patient survival. The prognosis of MYC translocation positive DLBCL critically depends on the second hit, with TP53 mutations and BCL2 translocation contributing to an adverse prognosis. It is pivotal to investigate both TP53 mutations and BCL2 translocations in MYC translocation positive DLBCL, and to distinguish double-hit DLBCLs from those with an isolated MYC translocation.

  4. Direct determination of the hit locations from experimental HPGe pulses

    Energy Technology Data Exchange (ETDEWEB)

    Désesquelles, P., E-mail: Pierre.Desesquelles@in2p3.fr [Univ. Paris-Sud, CSNSM CNRS/IN2P3, 15 rue G. Clémenceau, 91405 Orsay (France); Boston, A.J.; Boston, H.C.; Cresswell, J.R.; Dimmock, M.R. [Oliver Lodge Laboratory, The University of Liverpool, Oxford Street, Liverpool L69 7ZE (United Kingdom); Lazarus, I.H. [STFC Daresbury Laboratory, Daresbury, Warrington WA4 4AD (United Kingdom); Ljungvall, J. [Univ. Paris-Sud, CSNSM CNRS/IN2P3, 15 rue G. Clémenceau, 91405 Orsay (France); Nelson, L. [Oliver Lodge Laboratory, The University of Liverpool, Oxford Street, Liverpool L69 7ZE (United Kingdom); Nga, D.-T. [Univ. Paris-Sud, CSNSM CNRS/IN2P3, 15 rue G. Clémenceau, 91405 Orsay (France); Nolan, P.J.; Rigby, S.V. [Oliver Lodge Laboratory, The University of Liverpool, Oxford Street, Liverpool L69 7ZE (United Kingdom); Simpson, J. [STFC Daresbury Laboratory, Daresbury, Warrington WA4 4AD (United Kingdom); Van-Oanh, N.-T. [Univ. Paris-Sud, LCP UMR8000 CNRS, 15 rue G. Clémenceau, 91405 Orsay (France)

    2013-11-21

    The gamma-tracking technique optimises the determination of the energy and emission angle of gamma-rays detected by modern segmented HPGe detectors. This entails the determination, using the delivered pulse shapes, of the interaction points of the gamma-ray within the crystal. The direct method presented here allows the localisation of the hits using only a large sample of pulses detected in the actual operating conditions. No external crystal scanning system or pulse shape simulation code is needed. In order to validate this method, it is applied to sets of pulses obtained using the University of Liverpool scanning system. The hit locations are determined by the method with good precision.

  5. Bacterial contamination of street vending food in Kumasi, Ghana ...

    African Journals Online (AJOL)

    Street vending foods are readily available sources of meals for many people but the biological safe-ty of such food is always in doubt. The aim of this study is to ascertain bacterial isolate and deter-mine total counts of bacterial species responsible for the contamination of the street vending food in Kumasi so as to determine ...

  6. INTRODUCTION The term street children has many definitions in ...

    African Journals Online (AJOL)

    this, the still schooling street children in this study may likely have gravitated to the streets due to the lack of recreational facilities to keep youths occupied after school hours in the rural areas. As at the time of study, no amusement parks, cinemas and other recreational places exists in the Local Government Area. It is known.

  7. India : Energy-Efficient Street Lighting--Implementation and Financing Solutions

    OpenAIRE

    World Bank

    2015-01-01

    There has been a clear need for energy-efficient (EE) technologies that can be applicable in the municipal street lighting sector. The objective of this manual is to support the preparation and implementation of street lighting projects in India, using performance contracting and other public private partnership-based delivery approaches. This manual draws upon global best practices, inclu...

  8. Drug Use among Street Children in Tehran, Iran: A Qualitative Study

    Directory of Open Access Journals (Sweden)

    Masoumeh eDejman

    2015-12-01

    Full Text Available Introduction and objective: Globally, children who work and live on the streets are at higher risk of undesired behavioral health outcomes, including increased drug use and abuse. Considering the rapid growth of this population in Iran and the lack of program planning that is partly due to a scarcity of research-based information, this study was conducted in 2013 to investigate drug use among street children in Tehran. Method: With a qualitative design, we conducted a Rapid Assessment and Response (RAS Survey of street children in Tehran, 2012-2013. Data were also obtained from ten focus group discussions with street children using semi-structured questionnaires and 27 in-depth interviews with key informants in governmental, non-governmental, and international organizations. Results: The variation in age at first use, type of drugs, and pattern of drug use were found based on ethnicity. Gypsy boys and girls reported consuming more alcohol than other groups. Drug use problems were commonly described among families of street children. Children whose parents had drug-use problems described using drugs earlier than other children. Informants reported that families with drug-related problems used children for procurement of drugs. Children themselves described using drugs to cope with stress, reduce physical and psychological stressors and problems such as fatigue, sadness, and pressure resulting from frequent failures in life. Conclusion: These results suggest that intervention and prevention programs dealing with drug use of street children in Iran should include family and peers when addressing drug use by street children.

  9. Plasma response to sustainment with imposed-dynamo current drive in HIT-SI and HIT-SI3

    Science.gov (United States)

    Hossack, A. C.; Jarboe, T. R.; Chandra, R. N.; Morgan, K. D.; Sutherland, D. A.; Penna, J. M.; Everson, C. J.; Nelson, B. A.

    2017-07-01

    The helicity injected torus—steady inductive (HIT-SI) program studies efficient, steady-state current drive for magnetic confinement plasmas using a novel experimental method. Stable, high-beta spheromaks have been sustained using steady, inductive current drive. Externally induced loop voltage and magnetic flux are oscillated together so that helicity and power injection are always positive, sustaining the edge plasma current indefinitely. Imposed-dynamo current drive (IDCD) theory further shows that the entire plasma current is sustained. The method is ideal for low aspect ratio, toroidal geometries with closed flux surfaces. Experimental studies of spheromak plasmas sustained with IDCD have shown stable magnetic profiles with evidence of pressure confinement. New measurements show coherent motion of a stable spheromak in response to the imposed perturbations. On the original device two helicity injectors were mounted on either side of the spheromak and the injected mode spectrum was predominantly n  =  1. Coherent, rigid motion indicates that the spheromak is stable and a lack of plasma-generated n  =  1 energy indicates that the maximum q is maintained below 1 during sustainment. Results from the HIT-SI3 device are also presented. Three inductive helicity injectors are mounted on one side of the spheromak flux conserver. Varying the relative injector phasing changes the injected mode spectrum which includes n  =  2, 3, and higher modes.

  10. OpenStreetMap Collaborative Prototype, Phase 1

    Science.gov (United States)

    Wolf, Eric B.; Matthews, Greg D.; McNinch, Kevin; Poore, Barbara S.

    2011-01-01

    Phase One of the OpenStreetMap Collaborative Prototype (OSMCP) attempts to determine if the open source software developed for the OpenStreetMap (OSM, http://www.openstreetmap.org) can be used for data contributions and improvements that meet or exceed the requirements for integration into The National Map (http://www.nationalmap.gov). OpenStreetMap Collaborative Prototype Phase One focused on road data aggregated at the state level by the Kansas Data Access and Support Center (DASC). Road data from the DASC were loaded into a system hosted by the U.S. Geological Survey (USGS) National Geospatial Technical Operations Center (NGTOC) in Rolla, Missouri. U.S. Geological Survey editing specifications were developed by NGTOC personnel (J. Walters and G. Matthews, USGS, unpub. report, 2010). Interstate and U.S. Highways in the dataset were edited to the specifications by NGTOC personnel while State roads were edited by DASC personnel. Resulting data were successfully improved to meet standards for The National Map once the system and specifications were in place. The OSM software proved effective in providing a usable platform for collaborative data editing

  11. The on-street parking premium and car drivers' choice between street and garage parking

    NARCIS (Netherlands)

    Kobus, M.B.W.; Gutierrez Puigarnau, E.; Rietveld, P.; van Ommeren, J.N.

    2013-01-01

    We introduce a methodology to estimate the effect of parking prices on car drivers' choice between street and garage parking. Our key identifying assumption is that the marginal benefit of parking duration does not depend on this choice. The endogeneity of parking duration is acknowledged in the

  12. Faktor yang berhubungan dengan preferensi konsumen street food pada mahasiswa Universitas Gadjah Mada

    Directory of Open Access Journals (Sweden)

    Endah Budi Permana P.

    2016-08-01

    Full Text Available ABSTRACTBackground: Habits and preferences influence the street food consumption. Consuming of foods that are high in fat, protein, and carbohydrate could increase the risk to suffered from coronary heart  diseases, high blood pressure, diabetes mellitus, and stroke. More than 90% diseases that occurs in human were caused by food contamination of microorganisms, likes typhus and hepatitis A.Objectives:To analyze factors related to street food consumer preferences of Universitas Gadjah Mada’s students.Methods:This was an observational research with cross sectional design. Samples were 96 UGM’s undergraduate students of the year 2012 taken by cluster sampling. Datas were obtained by interview using questionnaire consumer preferences of street food and the individual and food characteristics. Data were then analysed by statistical analysis using correlation test (contingency coeffi cient and Spearman and multivariate analysis using logistic regression.Results: There was correlation between sex (RR:1.60, p=0.012, income (RR:1.36, p=0.017 and food prices (RR:0.52, p=0.001 with preference of street food meal.There was correlation between knowledge about nutrition (RR:27.75, p=0.000 and hygiene and sanitation (RR:1.25, p=0.000 with preference of street food on fruit group at Universitas Gadjah Mada’s students.Conclusions: Sex, income, and food prices related to preference of street food on meal. Knowledge about nutrition and hygiene sanitation related to preference of fruit group street food of Universitas Gadjah Mada’s students.KEYWORDS: food preference, consumer, street food, university students ABSTRAKLatar belakang: Kebiasaan dan preferensi seseorang akan sangat mempengaruhi konsumsi street food. Mengonsumsi makanan tinggi lemak, protein, dan karbohidrat dapat meningkatkan risiko terserang penyakit jantung koroner, tekanan darah tinggi, diabetes mellitus, dan stroke. Lebih dari 90% penyakit yang terjadi pada manusia disebabkan oleh

  13. [Agnosia for streets and defective root finding].

    Science.gov (United States)

    Takahashi, Nobuyoshi

    2011-08-01

    Topographical disorientation is identified as a condition in which patients are unable to find their way in familiar surroundings, such as their home neighborhood or the admitting hospital after the onset of illness. I proposed to classify topographical disorientation into two categories: agnosia for streets (landmark agnosia) and defective root finding (heading disorientation). Patients with agnosia for streets are unable to identify familiar buildings and landscapes. They can, however, morphologically perceive them and remember their way around familiar areas. The lesions are located in the right posterior part of the parahippocampus gyrus, anterior half of the lingual gyrus and adjacent fusiform gyrus. Clinical findings and functional imaging studies suggest that these regions play a crucial role in the interaction between the visual information of streets and memories of them, which are thought to be retained in the right anterior part of the temporal lobe. In particular, the posterior part of the parahippocampus gyrus is critical for the acquisition of novel information. On the other hand, patients with defective root finding can identify familiar streets, but cannot remember their own location or positional relation between two points within a comparatively wide range not surveyable at one time. The lesions are located in the right retrosplenial cortex (Areas 29, 30), posterior cingulate cortex (Areas 23, 31) and precuneus. Clinical findings and functional imaging studies suggest that these regions are involved in the orientation function for navigating in wide spaces. In particular, the retrosplenial cortex is critical for encoding novel information.

  14. Agnosia for streets and defective root finding

    International Nuclear Information System (INIS)

    Takahashi, Nobuyoshi

    2011-01-01

    Topographical disorientation is identified as a condition in which patients are unable to find their way in familiar surroundings, such as their home neighborhood or the admitting hospital after the onset of illness. I proposed to classify topographical disorientation into two categories: agnosia for streets (landmark agnosia) and defective root finding (heading disorientation). Patients with agnosia for streets are unable to identify familiar buildings and landscapes. They can, however, morphologically perceive them and remember their way around familiar areas. The lesions are located in the right posterior part of the parahippocampus gyrus, anterior half of the lingual gyrus and adjacent fusiform gyrus. Clinical findings and functional imaging studies suggest that these regions play a crucial role in the interaction between the visual information of streets and memories of them, which are thought to be retained in the right anterior part of the temporal lobe. In particular, the posterior part of the parahippocampus gyrus is critical for the acquisition of novel information. On the other hand, patients with defective root finding can identify familiar streets, but cannot remember their own location or positional relation between two points within a comparatively wide range not surveyable at one time. The lesions are located in the right retrosplenial cortex (Areas 29, 30), posterior cingulate cortex (Areas 23, 31) and precuneus. Clinical findings and functional imaging studies suggest that these regions are involved in the orientation function for navigating in wide spaces. In particular, the retrosplenial cortex is critical for encoding novel information. (author)

  15. Importance-satisfaction analysis of street food sanitation and choice factor in Korea and Taiwan

    Science.gov (United States)

    Joo, Nami; Park, Sanghyun; Lee, Bohee

    2015-01-01

    BACKGROUND/OBJECTIVES The present study investigated Korean and Taiwan adults on the importance of and the satisfaction with street food sanitation and street food choice factor, in order to present management and improvement measures for street foods. SUBJECTS/METHODS The present study conducted a survey on 400 randomly chosen adults (200 Korean, 200 Taiwanese). General characteristics, eating habits, street food intake frequency, and preference by type of street food of respondents were checked. Respondents' importance and satisfaction of street food hygiene and selection attributes were also measured. In order to test for the difference between groups, χ2-test and t-test were performed. ISA was also performed to analyze importance and satisfaction. RESULTS Results showed that the importance of sanitation was significantly higher than satisfaction on all items in both Korea and Taiwan, and the satisfaction with sanitation was higher in Taiwan than in Korea. According to ISA results with street food sanitation, satisfaction was low while importance was high in both Korea and Taiwan. In terms of street food choice factor, importance scores were significantly higher than satisfaction scores on all items. In addition, satisfaction scores on all items except 'taste' were significantly higher in Taiwan than in Korea. CONCLUSIONS A manual on sanitation management of street foods should be developed to change the knowledge and attitude toward sanitation by putting into practice a regularly conducted education. Considering the popularity of street foods and its potential as a tourism resource to easily publicize our food culture, thorough management measures should be prepared on sanitation so that safe street food culture should be created. PMID:26060542

  16. Moving targets: Promoting physical activity in public spaces via open streets in the US.

    Science.gov (United States)

    Hipp, J Aaron; Bird, Alyssa; van Bakergem, Margaret; Yarnall, Elizabeth

    2017-10-01

    Popularity of Open Streets, temporarily opening streets to communities and closing streets to vehicles, in the US has recently surged. As of January 2016, 122 cities have hosted an Open Streets program. Even with this great expansion, the sustainability of Open Streets remains a challenge in many cities and overall Open Streets in the US differ from their successful counterparts in Central and South America. Between summer 2015 and winter 2016, we reviewed the websites and social media of the 122 identified programs and interviewed 32 unique Open Streets programs. Websites and social media were reviewed for program initiation, number of Open Streets days, length of routes, duration of program, and reported participation. Interview questions focused on barriers and facilitators of expanding Open Streets and specific questioning regarding local evaluation activities. All interviews were transcribed verbatim and analyzed with constant comparative methodology. Over three-quarters of US Open Streets programs have been initiated since 2010, with median frequency of one time per year, 4h per date, and 5000-9999 participants. Seventy-seven percent of program routes are under 5km in length. Success of programs was measured by enthusiasm, attendance, social media, survey metrics, and sustainability. Thirteen of 32 program organizers expressed interest in expanding their programs to 12 dates per year, but noted consistent barriers to expansion including funding, permitting, and branding. Though many cities now host Open Streets programs, their ability to effect public health remains limited with few program dates per year. Coordinated efforts, especially around funding, permitting, and branding may assist in expanding program dates. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. Auroral vortex street formed by the magnetosphere–ionosphere coupling instability

    Directory of Open Access Journals (Sweden)

    Y. Hiraki

    2015-02-01

    Full Text Available By performing three-dimensional magnetohydrodynamic simulations including Alfvén eigenmode perturbations most unstable to the ionospheric feedback effects, we examined the auroral vortex street that often appears just before substorm onset. We found that an initially placed arc splits, intensifies, and rapidly deforms into a vortex street. We also found that there is a critical convection electric field for growth of the Alfvén eigenmodes. The vortex street is shown to be a consequence of coupling between the magnetospheric Alfvén waves carrying field-aligned currents and the ionospheric density waves driven by Pedersen/Hall currents.

  18. Auroral vortex street formed by the magnetosphere-ionosphere coupling instability

    Science.gov (United States)

    Hiraki, Y.

    2015-02-01

    By performing three-dimensional magnetohydrodynamic simulations including Alfvén eigenmode perturbations most unstable to the ionospheric feedback effects, we examined the auroral vortex street that often appears just before substorm onset. We found that an initially placed arc splits, intensifies, and rapidly deforms into a vortex street. We also found that there is a critical convection electric field for growth of the Alfvén eigenmodes. The vortex street is shown to be a consequence of coupling between the magnetospheric Alfvén waves carrying field-aligned currents and the ionospheric density waves driven by Pedersen/Hall currents.

  19. Street vending and informal economy: Survey data from Cali, Colombia.

    Science.gov (United States)

    Martinez, Lina M; Estrada, Daniela

    2017-10-01

    This data brief describes data collected in Cali, Colombia about the economic dynamic and socioeconomic conditions of street vendors in the city. The study was conducted between 2014 and 2016 in two populated sites in terms of formal and informal commerce in the city. We present the methodology followed in the study, location of street vending sites and type of data collected to approximate to the economic dimension of street vending. Data collected contains information about sociodemographic characteristics, life satisfaction, business operation and characteristics, income and expenses, official license for operation. This information is linked to the publication (Martinez et al., 2017) [1].

  20. Trees and Streets as Drivers of Urban Stormwater Nutrient Pollution.

    Science.gov (United States)

    Janke, Benjamin D; Finlay, Jacques C; Hobbie, Sarah E

    2017-09-05

    Expansion of tree cover is a major management goal in cities because of the substantial benefits provided to people, and potentially to water quality through reduction of stormwater volume by interception. However, few studies have addressed the full range of potential impacts of trees on urban runoff, which includes deposition of nutrient-rich leaf litter onto streets connected to storm drains. We analyzed the influence of trees on stormwater nitrogen and phosphorus export across 19 urban watersheds in Minneapolis-St. Paul, MN, U.S.A., and at the scale of individual streets within one residential watershed. Stormwater nutrient concentrations were highly variable across watersheds and strongly related to tree canopy over streets, especially for phosphorus. Stormwater nutrient loads were primarily related to road density, the dominant control over runoff volume. Street canopy exerted opposing effects on loading, where elevated nutrient concentrations from trees near roads outweighed the weak influence of trees on runoff reduction. These results demonstrate that vegetation near streets contributes substantially to stormwater nutrient pollution, and therefore to eutrophication of urban surface waters. Urban landscape design and management that account for trees as nutrient pollution sources could improve water quality outcomes, while allowing cities to enjoy the myriad benefits of urban forests.

  1. Isolated orbital mass as the primary presentation of a triple-hit lymphoma transformed from a systemic follicular lymphoma

    Directory of Open Access Journals (Sweden)

    Xiao Yi Zhou

    2018-06-01

    Full Text Available Purpose: Triple-hit lymphoma is a highly aggressive B-cell lymphoma. We report a case of triple-hit lymphoma transformed from systemic follicular lymphoma (FL after 9-year remission and presented primarily as an isolated orbital mass without systemic symptoms or lymphadenopathy. Observations: A 58-year-old female presented with intermittent vertical binocular diplopia, left upper eyelid swelling and pain and was found to have a 2.9 cm orbital mass. Histological section revealed a CD10-positive large B-cell lymphoma, consistent with transformation of FL. Fluorescent in situ hybridization (FISH analysis demonstrated rearrangements involving C-MYC, BCL-2 and BCL-6 genes, indicating a high grade, triple-hit lymphoma. Conclusions and importance: Triple-hit lymphoma transformed from a low-grade lymphoma may initially present as an isolated orbital mass without systemic evidence of transformation. Early recognition of double or triple-hit lymphomas is important since these patients require aggressive chemotherapy. Keywords: Lymphoma, Triple-hit lymphoma, Orbital mass

  2. Numerical Study of Traffic Pollutant Dispersion within Different Street Canyon Configurations

    Directory of Open Access Journals (Sweden)

    Yucong Miao

    2014-01-01

    Full Text Available The objective of this study is to numerically study flow and traffic exhaust dispersion in urban street canyons with different configurations to find out the urban-planning strategies to ease the air pollution. The Computational Fluid Dynamics (CFD model used in this study—Open Source Field Operation and Manipulation (OpenFOAM software package—was firstly validated against the wind-tunnel experiment data by using three different k-ε turbulence models. And then the patterns of flow and dispersion within three different kinds of street canyon configuration under the perpendicular approaching flow were numerically studied. The result showed that the width and height of building can dramatically affect the pollution level inside the street canyon. As the width or height of building increases, the pollution at the pedestrian level increases. And the asymmetric configuration (step-up or step-down street canyon could provide better ventilation. It is recommended to design a street canyon with nonuniform configurations. And the OpenFOAM software package can be used as a reliable tool to study flows and dispersions around buildings.

  3. Street children turn to sex-work to survive.

    Science.gov (United States)

    1995-08-01

    The Kenyan government currently deports tourists who are caught with child prostitutes and charges the children with prostitution. A harder treatment of foreigners caught with child prostitutes may soon emerge. The Undugu Society in Kenya, an organization working with street children, welcomes such changes. It teaches children practical skills, e.g., tailoring and carpentry. The Society has four schools and sponsors 1000 children to attend school or workshops. It sends social workers into the slums to counsel and gain the trust of street children as well as to encourage them to attend workshops. The Society has workshops on HIV transmission and emphasizes behavior change rather than condom use. Kenyan law prohibits adults from having sex with a child less than 18 years old. Juvenile courts deal with children caught engaging in solicitation of customers and/or prostitution. Children found guilty go to children's homes for rehabilitation into mainstream society. More and more countries of sex-tourists are punishing tourists who engage in sexual intercourse with minors in Kenya. Fear that high-profile cases will harm the multi-million-dollar tourist industry as well as lack of state resources makes Kenya reluctant to prosecute tourists. In 1994, most of Nairobi's 40,000 street children were engaged in prostitution. The leading centers of child prostitution are all tourist areas: Nairobi, Mombasa, Malindi, Lamu, and Diani. 80% of pornographic material in Kenya features children. Kenyan taxi drivers, tour guides, and hotel workers serve as middlemen in child prostitution. Urban poverty forces many children on to the streets. Rural children sent to urban areas to work as maids or servants in a rich house are often sexually abused. They then escape to the streets. Many child prostitutes come from poor families and have low literacy and no practical skills. AIDS orphans also become prostitutes to survive.

  4. Lower bounds on the periodic Hamming correlations of frequency hopping sequences with low hit zone

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    In this paper, several periodic Hamming correlation lower bounds for frequency hopping sequences with low hit zone, with respect to the size p of the frequency slot set, the sequence length L, the family size M, low hit zone LH ( or no hit zone NH ), the maximum periodic Hamming autocorrelation sidelobe Ha and the maximum periodic Hamming crosscorrelation Hc, are established. It is shown that the new bounds include the known Lempel-Greenberger bounds, T.S. Seay bounds and Peng-Fan bounds for the conventional frequency hopping sequences as special cases.

  5. 75 FR 6398 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee's...

    Science.gov (United States)

    2010-02-09

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the National Coordinator for Health Information Technology; HIT Policy Committee's Adoption/Certification Workgroup Meeting; Notice of Meeting AGENCY: Office... of Committee: HIT Policy Committee's Adoption/Certification Workgroup. General Function of the...

  6. Do repeated rumble strip hits improve driver alertness?

    NARCIS (Netherlands)

    Watling, C.N.; Akerstedt, T.; Kecklund, L.G.; Anund, A.

    2016-01-01

    Driving while sleepy is associated with increased crash risk. Rumble strips are designed to alert a sleepy or inattentive driver when they deviate outside their driving lane. The current study sought to examine the effects of repeated rumble strip hits on levels of physiological and subjective

  7. Pollutant Dilution and Diffusion in Urban Street Canyon Neighboring Streets

    Science.gov (United States)

    Sun, Z.; Fu, Zh. M.

    2011-09-01

    In the present study we investigated the airflow patterns and air quality of a series of typical street canyon combinations, developed a mass balance model to determine the local pollutant dilution rate, and discuss the impact of upstream canyon on the air quality of downstream canyon. The results indicated that the geometrical size of upstream and downstream buildings have significant impacts on the ambient airflow patterns. The pollution distribution within the canyons varies with different building combinations and flow patterns. Within the upstream canyon, pollution always accumulates to the low building side for non-symmetrical canyon, and for symmetrical canyon high level of pollution occurs at the leeward side. The height of the middle and downstream buildings can evidently change the pollutant dispersion direction during the transport process. Within the polluted canyon, the pollutant dilution rate (PDR) also varies with different street canyon combinations. The highest PDR is observed when the upstream buildings are both low buildings no matter the height of downstream building. However, the two cases are likely to contribution pollution to the downstream canyon. The H-L-H combination is mostly against local pollution remove, while the L-H-L case is considered the best optimistic building combination with both the ability of diluting local pollution and not remarkably decreasing air quality of downstream canyon. The current work is expected instructive for city designers to optimize traffic patterns under typical existing geometry or in the development of urban geometry modification for air quality control.

  8. Hot-spot analysis applied to the identification of potential high and low regulating, providing and cultural ecosystem services in Vilnius Region (Lithuania)

    Science.gov (United States)

    Pereira, Paulo; Daniel, Depellegrin; Egarter-Vigl, Lukas; Cerda, Artemi; Estebaranz, Ferran; Misiune, Ieva

    2017-04-01

    Ecosystem services (ES) potential assessment is crucial for a correct territorial planning at different scales of analysis (Depellegrin et al., 2016). In urban and peri-urban areas, sprawl, grazing and unsustainable agriculture practices contributed to land degradation and de decrease of the quality and quantity of the services provided by these areas (Eldridge and Delgado-Baquerizo, 2017; Favretto et al., 2017). In order to understand the spatial pattern of these impacts, mapping ES potential is key to understand the areas that need to be restored and protected for an unsustainable use (Brevik et al., 2016; Egarter-Vigl et al., 2017; Pereira et al., 2017). Hot-spot analysis is a good method to identify clusters of areas with high and low capacity for ES capacity. This analysis is very useful to detect homogeneous areas, where ES have high or low quality. The objective of this work is to apply a hot-spot analysis to detect areas with high/low capacity for Regulating, Provision, Cultural and Total ES in Vilnius region. ES potential was carried out based on the matrix developed by Burkhard et al. (2009), which ranks ES capacity from 0= no capacity to 5=very high relevant capacity to a different land use type. The results showed that regulating, providing and cultural and total ES have a significant dispersed (low-clustered) pattern: Regulating (Z-score=-19.28, pInternational Journal of Sustainable Development and World Ecology, 23, 441-455. Egarter-Vigl, L., Depellegrin, D., Pereira, P., De Groot, D., Tappeiner, U. (2017) Mapping the ecosystem service delivery chain: Capacity, flow, and demand pertaining to aesthetic experiences in mountain landscapes, Science of the Total Environment, 574, 442-436. Eldridge, D.J., Delgado-Baquerizo, M. (2017) Continental-scale impacts of livestock grazing on ecosystem supporting and regulating services. Land Degradation and Development. DOI: 10.1002/ldr.2668 Favretto, N., Lueding, E., Stringer, L., Dougill, A.J. (2017) Valuing

  9. Street prostitution zones and crime

    NARCIS (Netherlands)

    Bisschop, P.; Kastoryano, S.; van der Klaauw, B.

    2017-01-01

    This paper studies the effects of legal street prostitution zones on registered and perceived crime. We exploit a unique setting in the Netherlands where these tippelzones were opened in nine cities under different regulation systems. Our difference-in-difference analysis of 25 Dutch cities between

  10. Impact of aspect ratio and solar heating on street canyon air temperature

    International Nuclear Information System (INIS)

    Memon, R.A.; Lal, K.

    2011-01-01

    The results obtained from RNG (Re-Normalization Group) version of k-and turbulence model are reported in this study. The model is adopted to elucidate the impact of different building aspect ratios (i.e., ratio of building-height-to-street-canyon-width) and solar heating on temperatures in street canyon. The validation of Navier-Stokes and energy an sport equations showed that the model prediction for air-temperature and ambient wind provides reasonable accuracy. The model was applied on AR (Aspect Ratios) one to eight and surface temperature difference (delta and theta/sub s-a/)) of 2 -8. Notably, air-temperatures were higher in high AR street canyons in particular on the leeward side of the street canyon. Further investigation showed that the difference between the air-temperature 'high and low AR street canyons (AR) was positive and high with higher delta and theta/sub s-a/) conversely, the AR become negative and low gradually with lower values of delta and theta(/sub s-a/). These results could be very beneficial for the city and regional planners, civil engineers Id HVAC experts who design street canyons and strive for human thermal comfort with minimum possible energy requirements. (author)

  11. Impact of Aspect Ratio and Solar Heating on Street Conyn Air Temperature

    Directory of Open Access Journals (Sweden)

    Rizwan Ahmed Memon

    2011-01-01

    Full Text Available The results obtained from RNG (Re-Normalization Group version of k-? turbulence model are reported in this study. The model is adopted to elucidate the impact of different building aspect ratios (i.e., ratio of building-height-to-street-canyon-width and solar heating on temperatures in street canyon. The validation of Navier-Stokes and energy transport equations showed that the model prediction for air-temperature and ambient wind provides reasonable accuracy. The model was applied on AR (Aspect Ratios one to eight and surface temperature difference (??s-a of 2 -8. Notably, air-temperatures were higher in high AR street canyons in particular on the leeward side of the street canyon. Further investigation showed that the difference between the air-temperature of high and low AR street canyons ( AR was positive and high with higher ??s-a. Conversely, the AR become negative and low gradually with lower values of ??s-a. These results could be very beneficial for the city and regional planners, civil engineers and HVAC experts who design street canyons and strive for human thermal comfort with minimum possible energy requirements.

  12. Dispersion and photochemical evolution of reactive pollutants in street canyons

    Science.gov (United States)

    Kwak, Kyung-Hwan; Baik, Jong-Jin; Lee, Kwang-Yeon

    2013-05-01

    Dispersion and photochemical evolution of reactive pollutants in street canyons with canyon aspect ratios of 1 and 2 are investigated using a computational fluid dynamics (CFD) model coupled with the carbon bond mechanism IV (CBM-IV). Photochemical ages of NOx and VOC are expressed as a function of the NO2-to-NOx and toluene-to-xylene ratios, respectively. These are found to be useful for analyzing the O3 and OH oxidation processes in the street canyons. The OH oxidation process (O3 oxidation process) is more pronounced in the upper (lower) region of the street canyon with a canyon aspect ratio of 2, which is characterized by more (less) aged air. In the upper region of the street canyon, O3 is chemically produced as well as transported downward across the roof level, whereas O3 is chemically reduced in the lower region of the street canyon. The O3 chemical production is generally favorable when the normalized photochemical ages of NOx and VOC are larger than 0.55 and 0.28, respectively. The sensitivities of O3 chemical characteristics to NOx and VOC emission rates, photolysis rate, and ambient wind speed are examined for the lower and upper regions of the street canyon with a canyon aspect ratio of 2. The O3 concentration and the O3 chemical production rate divided by the O3 concentration increase as the NOx emission rate decreases and the VOC emission rate and photolysis rate increase. The O3 concentration is less sensitive to the ambient wind speed than to other factors considered. The relative importance of the OH oxidation process compared to the O3 oxidation process increases with increasing NOx emission rate and photolysis rate and decreasing VOC emission rate. In this study, both O3 and OH oxidation processes are found to be important in street-canyon scale chemistry. The methodology of estimating the photochemical ages can potentially be adopted to neighborhood scale chemistry.

  13. Screening and hit evaluation of a chemical library against blood-stage Plasmodium falciparum.

    Science.gov (United States)

    Avery, Vicky M; Bashyam, Sridevi; Burrows, Jeremy N; Duffy, Sandra; Papadatos, George; Puthukkuti, Shyni; Sambandan, Yuvaraj; Singh, Shivendra; Spangenberg, Thomas; Waterson, David; Willis, Paul

    2014-05-27

    In view of the need to continuously feed the pipeline with new anti-malarial agents adapted to differentiated and more stringent target product profiles (e.g., new modes of action, transmission-blocking activity or long-duration chemo-protection), a chemical library consisting of more than 250,000 compounds has been evaluated in a blood-stage Plasmodium falciparum growth inhibition assay and further assessed for chemical diversity and novelty. The selection cascade used for the triaging of hits from the chemical library started with a robust three-step in vitro assay followed by an in silico analysis of the resulting confirmed hits. Upon reaching the predefined requirements for selectivity and potency, the set of hits was subjected to computational analysis to assess chemical properties and diversity. Furthermore, known marketed anti-malarial drugs were co-clustered acting as 'signposts' in the chemical space defined by the hits. Then, in cerebro evaluation of the chemical structures was performed to identify scaffolds that currently are or have been the focus of anti-malarial medicinal chemistry programmes. Next, prioritization according to relaxed physicochemical parameters took place, along with the search for structural analogues. Ultimately, synthesis of novel chemotypes with desired properties was performed and the resulting compounds were subsequently retested in a P. falciparum growth inhibition assay. This screening campaign led to a 1.25% primary hit rate, which decreased to 0.77% upon confirmatory repeat screening. With the predefined potency (EC₅₀  10) criteria, 178 compounds progressed to the next steps where chemical diversity, physicochemical properties and novelty assessment were taken into account. This resulted in the selection of 15 distinct chemical series. A selection cascade was applied to prioritize hits resulting from the screening of a medium-sized chemical library against blood-stage P. falciparum. Emphasis was placed on chemical

  14. Developing an indicators plan and software for evaluating Street Cleanliness and Waste Collection Services

    Directory of Open Access Journals (Sweden)

    Iago López

    2017-12-01

    Full Text Available An app to evaluate the Street Cleanliness and Waste Collection Service was developed. This app is based on a Plan of Indicators that can be used to evaluate the Street Cleanliness and Waste Collection Service of Santander municipality. Specific methodologies for calculating and evaluating 59 indicators have been developed to obtain information regarding the status of the different elements of the service. The Plan of Indicators has been applied to Santander city. The app was designed to address, but is not limited to, the following goals: i to obtain, store and calculate information regarding the above indicators and ii to disseminate the results of the status of the elements of the Service to the public sector. The app that was developed can provide a quick view of the results obtained for each indicator in each district, which is useful for making an appropriate diagnosis of the city’s cleanliness and is the first step in the decision making and Service optimisation processes. Detailed results for the Street Cleanliness Index are shown for each district of Santander city. The Street Cleanliness Index values are also related to the Frequency Street Cleanliness Services parameters. Pearson correlation coefficient results suggest that an inverse relationship between the Street Cleanliness Index values and the Frequency Street Cleanliness Services/population density ratio exists (R2 = −0.63. The results show that Street Cleanliness Index worst values exist for those districts that have a lower Frequency Street Cleanliness Services /population density parameter. The results are useful for designing and optimising the Street Cleanliness Service. For the decision making process, resources should be allocated where necessary, which seems to be those districts with lower Frequency Street Cleanliness Services /population density ratios.

  15. Hit size effectiveness in relation to the microdosimetric site size

    International Nuclear Information System (INIS)

    Varma, M.N.; Wuu, C.S.; Zaider, M.

    1994-01-01

    This paper examines the effect of site size (that is, the diameter of the microdosimetric volume) on the hit size effectiveness function (HSEF), q(y), for several endpoints relevant in radiation protection. A Bayesian and maximum entropy approach is used to solve the integral equations that determine, given microdosimetric spectra and measured initial slopes, the function q(y). All microdosimetric spectra have been calculated de novo. The somewhat surprising conclusion of this analysis is that site size plays only a minor role in selecting the hit size effectiveness function q(y). It thus appears that practical means (e.g. conventional proportional counters) are already at hand to actually implement the HSEF as a radiation protection tool. (Author)

  16. A Solution for Street Lighting in Smart Cities

    OpenAIRE

    M. Popa; A. Marcu

    2012-01-01

    Smart Cities is a domain of great interest in the modern society. The aim of a smart urban environment is to increase citizens’ comfort and quality of life with minimum resources and power consumption and without affecting the natural environment. Street lighting is one of the main interests in such a smart environment. This thesis focuses on implementing a lighting control system that makes street lighting to be an autonomous and efficient part of the urban environment. The performance of th...

  17. Road dust emission sources and assessment of street washing effect

    NARCIS (Netherlands)

    Karanasiou, A.; Amato, F.; Moreno, T.; Lumbreras, J.; Borge, R.; Linares, C.; Boldo, E.; Alastuey, A.; Querol, X.

    2014-01-01

    Although previous studies report on the effect of street washing on ambient particulate matter levels, there is a lack of studies investigating the results of street washing on the emission strength of road dust. A sampling campaign was conducted in Madrid urban area during July 2009 where road dust

  18. Health problems of street children and women in Awassa, Southern ...

    African Journals Online (AJOL)

    Background: The number of street children and women in major towns of Ethiopia is rapidly increasing. Yet their problems have not been fully studied. Objective: To assess health and related problems in street children and women. Methods: A cross sectional survey was conducted in Awassa town, women southern ...

  19. Redesigning Main Streets in Small Communities: The Viagra of Transportation Investment

    Science.gov (United States)

    1998-09-16

    The national Main Street movement is building momentum. Over 1,200 small : communities across America have rediscovered their Main Streets with impressive : investment in time, energy and money. The tangible measures of return include: : economic gro...

  20. The Rock that Hit New York

    Energy Technology Data Exchange (ETDEWEB)

    Meade, Roger Allen [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Keksis, August Lawrence [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-10-03

    On January 12, 1975, a rock seemed to fall from the sky over New York State’s Schoharie County hitting the tractor of a local farmer, who was “preparing his fields for spring planting.” As the farmer later described the event to a reporter from the UFO INVESTIGATOR, the object glanced off the tractor, fell to the ground, and melted its way through a patch of ice that was two and one half inches thick. The farmer, Leonard Tillapaugh, called the county sheriff, Harvey Stoddard, who recovered the rock, noting that it “was still warm.” Why and how a sample of the rock came to Los Alamos is not known. However, it captivated a wide Laboratory audience, was subjected to rigorous testing and evaluation. Los Alamos used the scientific method in the manner promoted by Hynek. Did Los Alamos solve the mystery of the rock’s origin? Not definitively. Although the exact origin could not be determined, it was shown conclusively that the rock was not from outer space. With that said, the saga of Rock that hit New York came to an end. Nothing more was said or written about it. The principals involved have long since passed from the scene. The NICAP ceased operations in 1980. And, the rock, itself, has disappeared.

  1. A Semiotic Reading and Discourse Analysis of Postmodern Street Performance

    Science.gov (United States)

    Lee, Mimi Miyoung; Chung, Sheng Kuan

    2009-01-01

    Postmodern street art operates under a set of references that requires art educators and researchers to adopt alternative analytical frameworks in order to understand its meanings. In this article, we describe social semiotics, critical discourse analysis, and postmodern street performance as well as the relevance of the former two in interpreting…

  2. Reviewing Hit Discovery Literature for Difficult Targets: Glutathione Transferase Omega-1 as an Example.

    Science.gov (United States)

    Xie, Yiyue; Dahlin, Jayme L; Oakley, Aaron J; Casarotto, Marco G; Board, Philip G; Baell, Jonathan B

    2018-05-10

    Early stage drug discovery reporting on relatively new or difficult targets is often associated with insufficient hit triage. Literature reviews of such targets seldom delve into the detail required to critically analyze the associated screening hits reported. Here we take the enzyme glutathione transferase omega-1 (GSTO1-1) as an example of a relatively difficult target and review the associated literature involving small-molecule inhibitors. As part of this process we deliberately pay closer-than-usual attention to assay interference and hit quality aspects. We believe this Perspective will be a useful guide for future development of GSTO1-1 inhibitors, as well serving as a template for future review formats of new or difficult targets.

  3. Georges Charpak street sign unveiled

    CERN Multimedia

    Paola Catapano

    2011-01-01

    While it might not be the only French street named in honour of the late Georges Charpak, who passed away in September 2010 at the age of 87, the street chosen by the mayor of Saint-Genis-Pouilly is certainly the only one located directly opposite the CERN "campus". The road overlooks buildings on the CERN Meyrin site, where Georges Charpak spent most of his career as a physicist, conducting the research that won him the Nobel Prize in Physics in 1992.   From left to right: Sigurd Lettow, Dominique Charpak and the mayor of Saint-Genis-Pouilly. The unveiling took place on 17 October and was organised by the mayor of Saint-Genis-Pouilly. George Charpak’s wife, Dominique, and Sigurd Lettow, CERN Director of Administration and General Infrastructure, attended what was an intimate and touching ceremony. The mayor’s speech at the event praised Georges’ commitment to scientific education. The highlight of the event, however, was a witty and humorous ...

  4. Synthetic Medicinal Chemistry in Chagas' Disease: Compounds at The Final Stage of "Hit-To-Lead" Phase.

    Science.gov (United States)

    Cerecetto, Hugo; González, Mercedes

    2010-03-25

    Chagas' disease, or American trypanosomosiasis, has been the most relevant illness produced by protozoa in Latin America. Synthetic medicinal chemistry efforts have provided an extensive number of chemodiverse hits at the "active-to-hit" stage. However, only a more limited number of these have been studied in vivo in models of Chagas' disease. Herein, we survey some of the cantidates able to surpass the "hit-to-lead" stage discussing their limitations or merit to enter in clinical trials in the short term.

  5. 76 FR 1432 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee...

    Science.gov (United States)

    2011-01-10

    ... Technology; HIT Standards Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of Meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Standards...

  6. 75 FR 8954 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee...

    Science.gov (United States)

    2010-02-26

    ... Technology; HIT Standards Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Standards...

  7. 75 FR 70923 - Office of the National Coordinator for Health Information Technology; HIT Policy Committee...

    Science.gov (United States)

    2010-11-19

    ... Technology; HIT Policy Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Policy Committee...

  8. 75 FR 70923 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee...

    Science.gov (United States)

    2010-11-19

    ... Technology; HIT Standards Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Standards...

  9. 75 FR 29761 - Office of the National Coordinator for Health Information Technology: HIT Standards Committee...

    Science.gov (United States)

    2010-05-27

    ... Technology: HIT Standards Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Standards...

  10. 76 FR 4354 - Office of the National Coordinator for Health Information Technology; HIT Standards Committee...

    Science.gov (United States)

    2011-01-25

    ... Technology; HIT Standards Committee Advisory Meeting; Notice of Meeting AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meeting. This notice announces a... Information Technology (ONC). The meeting will be open to the public. Name of Committee: HIT Standards...

  11. Modelling the air flow in symmetric and asymmetric street canyons

    Energy Technology Data Exchange (ETDEWEB)

    Santiago, J.L.; Martin, F. [Research Center for Energy, Environment and Technology (CIEMAT), Madrid (Spain). Fossil Fuels Dept., Numerical Simulation and Modelling Program

    2004-07-01

    In recent years a large amount of research has been conducted on urban scale and street canyon. Control of air quality inside cities is important for human health. To achieve this objective, street canyon modelling plays a significant role. Pollutant dispersion inside canyons are determined by wind flow around this complex geometry. Experimental investigations have been made by means of field measurements such as Vachon, G. et al. or wind tunnel experiences as Meroney, R.N. et al. or Kastner-Klein, P. and E.J. Plate. In many of these researches, they have used CFD models in several configurations, for instance Assimakopoulos, V.D. et al. or Sini, J.-F. et al. These models are based on a numerical resolution of Navier-Stokes equations with a turbulence closure. In this study, the aim is contribute to the understanding of air circulation inside street canyons. In order to achieve this purpose, several configurations of canyons are investigated. Two-dimensional sequences of real-scale street canyons (order to obstacles height is meters) with different features (symmetric canyons and asymmetric canyons forming step-up and step-down notch configurations) are simulated. These general configurations are modified to investigate some parameters such as aspect ratio, W/H, where W is the width of street and H is the height of buildings. Flows with high Reynolds numbers are modelling. FLUENT CFD software is used. (orig.)

  12. Multi-city assessment of lifetime pregnancy involvement among street youth, Ukraine.

    Science.gov (United States)

    Zapata, Lauren B; Kissin, Dmitry M; Robbins, Cheryl L; Finnerty, Erin; Skipalska, Halyna; Yorick, Roman V; Jamieson, Denise J; Marchbanks, Polly A; Hillis, Susan D

    2011-08-01

    Although street youth are at increased risk of lifetime pregnancy involvement (LPI), or ever becoming or getting someone pregnant, no reports to date describe the epidemiology of LPI among systematically sampled street youth from multiple cities outside of North America. The purpose of our assessment was to describe the prevalence of and risk factors associated with LPI among street youth from three Ukrainian cities. We used modified time-location sampling to conduct a cross-sectional assessment in Odesa, Kyiv, and Donetsk that included citywide mapping of 91 public venue locations frequented by street youth, random selection of 74 sites, and interviewing all eligible and consenting street youth aged 15-24 years found at sampled sites (n = 929). Characteristics of youth and prevalence of LPI overall and by demographic, social, sexual, and substance use risk factors, were estimated separately for males and females. Adjusted odds ratios (AORs) were calculated with multivariable logistic regression and effect modification by gender was examined. Most (96.6%) eligible youth consented to participate. LPI was reported for 41.7% of females (93/223) and 23.5% of males (166/706). For females, LPI was significantly elevated and highest (>70%) among those initiating sexual activity at ≤12 years and for those reporting lifetime anal sex and exchanging sex for goods. For males, LPI was significantly elevated and highest (>40%) among those who reported lifetime anal sex and history of a sexually transmitted infection. Overall, risk factors associated with LPI were similar for females and males. Among the total sample (females and males combined), significant independent risk factors with AORs ≥2.5 included female gender, being aged 20-24 years, having five to six total adverse childhood experiences, initiating sex at age ≤12 or 13-14 years, lifetime anal sex, most recent sex act unprotected, and lifetime exchange of sex for goods. Among street youth with LPI (n = 259), the

  13. Effectiveness of green infrastructure for improvement of air quality in urban street canyons.

    Science.gov (United States)

    Pugh, Thomas A M; Mackenzie, A Robert; Whyatt, J Duncan; Hewitt, C Nicholas

    2012-07-17

    Street-level concentrations of nitrogen dioxide (NO(2)) and particulate matter (PM) exceed public health standards in many cities, causing increased mortality and morbidity. Concentrations can be reduced by controlling emissions, increasing dispersion, or increasing deposition rates, but little attention has been paid to the latter as a pollution control method. Both NO(2) and PM are deposited onto surfaces at rates that vary according to the nature of the surface; deposition rates to vegetation are much higher than those to hard, built surfaces. Previously, city-scale studies have suggested that deposition to vegetation can make a very modest improvement (street canyons. This study shows that increasing deposition by the planting of vegetation in street canyons can reduce street-level concentrations in those canyons by as much as 40% for NO(2) and 60% for PM. Substantial street-level air quality improvements can be gained through action at the scale of a single street canyon or across city-sized areas of canyons. Moreover, vegetation will continue to offer benefits in the reduction of pollution even if the traffic source is removed from city centers. Thus, judicious use of vegetation can create an efficient urban pollutant filter, yielding rapid and sustained improvements in street-level air quality in dense urban areas.

  14. Comparison of Video Head Impulse Test (vHIT) Gains Between Two Commercially Available Devices and by Different Gain Analytical Methods.

    Science.gov (United States)

    Lee, Sang Hun; Yoo, Myung Hoon; Park, Jun Woo; Kang, Byung Chul; Yang, Chan Joo; Kang, Woo Suk; Ahn, Joong Ho; Chung, Jong Woo; Park, Hong Ju

    2018-06-01

    To evaluate whether video head impulse test (vHIT) gains are dependent on the measuring device and method of analysis. Prospective study. vHIT was performed in 25 healthy subjects using two devices simultaneously. vHIT gains were compared between these instruments and using five different methods of comparing position and velocity gains during head movement intervals. The two devices produced different vHIT gain results with the same method of analysis. There were also significant differences in the vHIT gains measured using different analytical methods. The gain analytic method that compares the areas under the velocity curve (AUC) of the head and eye movements during head movements showed lower vHIT gains than a method that compared the peak velocities of the head and eye movements. The former method produced the vHIT gain with the smallest standard deviation among the five procedures tested in this study. vHIT gains differ in normal subjects depending on the device and method of analysis used, suggesting that it is advisable for each device to have its own normal values. Gain calculations that compare the AUC of the head and eye movements during the head movements show the smallest variance.

  15. Philippines: street children, children at risk.

    Science.gov (United States)

    Tantoco, F G

    1993-01-01

    Almost 2 million of Manila's 2.5 million children younger than 15 years old live on or below the poverty line. 75,000 of these children live on the streets after having run away from home or being abandoned. They beg, steal, scavenge for food, and sell newspapers, cigarettes, and leis. About 20,000 of the street children prostitute themselves. It is these latter children and adolescents who are at particular risk of HIV infection. Studies in the Philippines indicate that 91% of reported HIV infections are among individuals aged 15-44, the male/female infection ratio is one to one, the transmission rate is 45%, and the most common mode of transmission is through heterosexual intercourse. The high incidence of child sexual abuse and child prostitution in the Philippines would suggest that there are a significant number of children and adolescents under age 15 who are infected with HIV. Caritas Manila has developed an information, education, and communication program for HIV/AIDS prevention focusing upon individuals who have direct influence upon and are in direct contact with people: clergy, religious and civic associations, educators, and social and health workers. Caritas has also to a limited extent reached out directly to populations at risk, while collaborating with human rights advocacy groups and networking with other children-oriented agencies in the interest of providing resources to street children. Efforts must be made to protect the rights of children and provide them with an environment conducive to their growth and development. The author notes how off-duty policemen in Manila help real estate developers forcibly eject the poor from their shelters to clear the way for the construction of new infrastructure without concern for the legal processes and requirements in the humane and peaceful relocation of the homeless poor. Many women and children are hurt and killed in the process. It has also been reported that off-duty policemen in Rio de Janeiro

  16. Effects of building roof greening on air quality in street canyons

    Science.gov (United States)

    Baik, Jong-Jin; Kwak, Kyung-Hwan; Park, Seung-Bu; Ryu, Young-Hee

    2012-12-01

    Building roof greening is a successful strategy for improving urban thermal environment. It is of theoretical interest and practical importance to study the effects of building roof greening on urban air quality in a systematic and quantitative way. In this study, we examine the effects of building roof greening on air quality in street canyons using a computational fluid dynamics (CFD) model that includes the thermodynamic energy equation and the transport equation of passive, non-reactive pollutants. For simplicity, building roof greening is represented by specified cooling. Results for a simple building configuration with a street canyon aspect ratio of one show that the cool air produced due to building roof greening flows into the street canyon, giving rise to strengthened street canyon flow. The strengthened street canyon flow enhances pollutant dispersion near the road, which decreases pollutant concentration there. Thus, building roof greening improves air quality near the road. The degree of air quality improvement near the road increases as the cooling intensity increases. In the middle region of the street canyon, the air quality can worsen when the cooling intensity is not too strong. Results for a real urban morphology also show that building roof greening improves air quality near roads. The degree of air quality improvement near roads due to building roof greening depends on the ambient wind direction. These findings provide a theoretical foundation for constructing green roofs for the purpose of improving air quality near roads or at a pedestrian level as well as urban thermal environment. Further studies using a CFD model coupled with a photochemistry model and a surface energy balance model are required to evaluate the effects of building roof greening on air quality in street canyons in a more realistic framework.

  17. The health profile of street children in Africa: a literature review

    Directory of Open Access Journals (Sweden)

    Samuel Nambile Cumber

    2015-08-01

    Full Text Available The United Nations Children’s Fund has labeled street children as children in difficult circumstances, which represent a minority population that has been under-represented for too long in health research. This is a concern because street children are at risk of carrying a greater disease burden. Their homeless lifestyle makes them more vulnerable to health risks and problems than children who live at home; as they roam the streets begging for food and money to obtain basic needs and are found sleeping in half-destroyed houses, abandoned basements, under bridges and in the open air. This paper presents health results from a systematic review of literature from 17 databases and including 16 countries in Africa. The review revealed that there are more boys than girls living on the street in their adolescence and who mainly have left home due to poverty and abuse. These children in these countries are vulnerable to poor health due to factors such as homelessness, risky sexual behavior, substance abuse and violence. Among the health problems identified are growth and nutritional disorders, physical injuries, violence, sexual abuse, communicable diseases including diarrheal diseases, malaria, respiratory diseases, neglected tropical diseases, mental health issues, substance abuse, reproductive health disorders, mortality, sexually transmitted diseases and HIV/AIDS. Primary interventions that could prevent poor health and improve the health status of street children include provision of safe shelter, proper nutrition, access to health care, health education, and sexual reproductive health, protection from any form of abuse, violence and substance abuse. Enforcing state policies and laws in all African countries is required to protect street children from neglect, abuse and to increase their access to education. More research on the health risks and health status of street children is still required, particularly in Sub-Saharan Africa, which carries

  18. The health profile of street children in Africa: a literature review

    Directory of Open Access Journals (Sweden)

    Samuel Nambile Cumber

    2016-08-01

    Full Text Available The United Nations Children’s Fund has labeled street children as children in difficult circumstances, which represent a minority population that has been under-represented for too long in health research. This is a concern because street children are at risk of carrying a greater disease burden. Their homeless lifestyle makes them more vulnerable to health risks and problems than children who live at home; as they roam the streets begging for food and money to obtain basic needs and are found sleeping in half-destroyed houses, abandoned basements, under bridges and in the open air. This paper presents health results from a systematic review of literature from 17 databases and including 16 countries in Africa. The review revealed that there are more boys than girls living on the street in their adolescence and who mainly have left home due to poverty and abuse. These children in these countries are vulnerable to poor health due to factors such as homelessness, risky sexual behavior, substance abuse and violence. Among the health problems identified are growth and nutritional disorders, physical injuries, violence, sexual abuse, communicable diseases including diarrheal diseases, malaria, respiratory diseases, neglected tropical diseases, mental health issues, substance abuse, reproductive health disorders, mortality, sexually transmitted diseases and HIV/AIDS. Primary interventions that could prevent poor health and improve the health status of street children include provision of safe shelter, proper nutrition, access to health care, health education, and sexual reproductive health, protection from any form of abuse, violence and substance abuse. Enforcing state policies and laws in all African countries is required to protect street children from neglect, abuse and to increase their access to education. More research on the health risks and health status of street children is still required, particularly in Sub-Saharan Africa, which carries

  19. Built environmental factors and adults' travel behaviors: Role of street layout and local destinations.

    Science.gov (United States)

    Koohsari, Mohammad Javad; Owen, Neville; Cole, Rachel; Mavoa, Suzanne; Oka, Koichiro; Hanibuchi, Tomoya; Sugiyama, Takemi

    2017-03-01

    Street layout is consistently associated with adults' travel behaviors, however factors influencing this association are unclear. We examined associations of street layout with travel behaviors: walking for transport (WT) and car use; and, the extent to which these relationships may be accounted for by availability of local destinations. A 24-h travel diary was completed in 2009 by 16,345 adult participants of the South-East Queensland Household Travel Survey, Australia. Three travel-behavior outcomes were derived: any home-based WT; over 30min of home-based WT; and, over 60min of car use. For street layout, a space syntax measure of street integration was calculated for each Statistical Area 1 (SA1, the smallest geographic unit in Australia). An objective measure of availability of destinations - Walk Score - was also derived for each SA1. Logistic regression examined associations of street layout with travel behaviors. Mediation analyses examined to what extent availability of destinations explained the associations. Street integration was significantly associated with travel behaviors. Each one-decile increment in street integration was associated with an 18% (95%CI: 1.15, 1.21) higher odds of any home-based WT; a 10% (95%CI: 1.06, 1.15) higher odds of over 30min of home-based WT; and a 5% (95%CI: 0.94, 0.96) lower odds of using a car over 60min. Local destinations partially mediated the effects of street layout on travel behaviors. Well-connected street layout contributes to active travel partially through availability of more local destinations. Urban design strategies need to address street layout and destinations to promote active travel among residents. Copyright © 2016 Elsevier Inc. All rights reserved.

  20. Identification of specific microorganisms in fresh squeezed street vended fruit juices

    Directory of Open Access Journals (Sweden)

    K Sahithi Reddy

    2016-01-01

    Full Text Available Introduction: In developing country like India, street foods such as salads and fresh cut fruits are widely consumed. Among all street foods, fruit juices are common beverages, consumed more because of higher consumer preference both in terms of taste and health. Moreover, there is a dearth of Indian studies on contamination of street vended fruit juices. Aim: To determine the pH and specific microorganisms in freshly squeezed street vended fruit juices. Materials and Methods: Four fruit juices i.e., Grapes, Sweet Lime, Pineapple and Sapota were chosen for the study. Juices were collected in summer season in months between April and June 2013. Ten samples of 50 ml each fruit juice was collected in sterile bottles from various street vendors of Dilshuknagar area of Hyderabad city. Transportation of samples to Food Toxicology laboratory, National Institute of Nutrition was done in the ice box and processing was done within 2–4 h. Results: All juices showed bacterial contamination except one sample of grape juice. Pineapple juice samples showed the high bacterial contamination with all samples positive for fecal coliforms and Shigella spp. (100%. Salmonella spp. was detected only in one sample of Sapota juice (10%. Significant difference among fruit juices for prevalence of microorganisms was seen only for Escherichia coli (P = 0.03 with least count in Grape juice (20%. Conclusion: Freshly squeezed street vended fruit juices were contaminated with pathogenic bacteria, which significantly attributed to public health problem.