WorldWideScience

Sample records for hiperplasia gingival por

  1. Analise da termoterapia transuretral por microondas no tratamento da hiperplasia benigna da prostata

    OpenAIRE

    Pedro Luiz Macedo Cortado

    1997-01-01

    Resumo: A hiperplasia benigna da próstata (HBP) é uma condição anátomo-patológica que se traduz por alterações clínicas, morfológicas e funcionais do trato urinário, sendo estimado que um terço de todos os homens necessitará de um procedimento cirúgico para aliviar a sintomatologia secundária à HBP. Até hoje, o melhor método para tratamento é o cirúrgico, através da ressecção endoscópica da próstata porém, as taxas de morbidade e mortalidade não são desprezíveis, bem como o alto custo das cir...

  2. Gingivitis

    Science.gov (United States)

    ... hygiene is the best way to prevent gingivitis. Brush your teeth at least twice a day. Floss at least ... dental hygienist to show you how to properly brush and floss your teeth. Your dentist may suggest devices to help remove ...

  3. Agrandamiento gingival inducido por nifedipina.Reporte de un caso

    Directory of Open Access Journals (Sweden)

    Antonio José Díaz Caballero

    2013-10-01

    Full Text Available ResumenEs bien conocido que el tratamiento con diversos tipos de medicamentos puede producir en las encías un crecimiento de este tejido. Se reporta que medicamentos tales como los bloqueadores de los canales de calcio, inmunosupresores, anticonvulsivantes pueden expresar esos efectos laterales. La nifedipina es la que principalmente se reporta que produce agrandamientos gingivales, al ser utilizada durante tratamientos largos para trastornos cardiovasculares, angina de pecho e hipertensión. Se presenta un caso de paciente varón de 60 años de edad, hipertenso, tratado con nifedipina, con agrandamientos gingivales. Se realiza fase higiénica y terapia quirúrgica con electro cirugía. La evolución y predecibilidad fueron favorables. (Duazary 2009 I; 51-55AbstractIt is well known that chronic medication with various drugs may cause gingival overgrowth. It has been reported that gingival overgrowth is induced by drugs such as calcium channel blockers and immunosuppressants. Nifedipine is most frequently reported to induce gingival overgrowth during long-term treatment of cardiovascular disorders such as hypertension and angina pectoris. A case of a 60 year old male patient with hypertension treated with nifedipine is presented. Electrosurgery treatment was performed; the evolution and prediction are favorable.Key Words: Nifedipine; Gingival Overgrowth; Calcium Cannel Blocker.

  4. Agrandamiento gingival por bloqueantes de canales de calcio

    OpenAIRE

    Ocaña Diestra, Tania; Facultad de Odontología, Universidad Nacional Mayor de San Marcos, Perú; García Linares, Sixto; Departamento Académico Médico Quirúrgico, Facultad de Odontología, Universidad Nacional Mayor de San Marcos, Perú

    2014-01-01

    Objetivo: Determinar la frecuencia del agrandamiento gingival en pacientes hipertensos que consumen fármacos bloqueantes de canales de calcio y compararlo con otro grupo de pacientes hipertensos que no consumen dichos fármacos. Métodos: En el estudio descriptivo transversal se evaluaron a 50 pacientes hipertensos que consumían bloqueantes de canales de calcio (grupo de estudio) y a 50 pacientes hipertensos que recibían tratamiento con otro tipo de antihipertensivos (grupo control). Se les rea...

  5. Estudo exploratório da utilização de saw palmetto no tratamento da hiperplasia benigna da próstata por urologistas de Porto Alegre

    Directory of Open Access Journals (Sweden)

    Gabriela Ferreira

    Full Text Available O objetivo deste trabalho foi avaliar a utilização de fitoterápicos a base de saw palmetto na terapia sintomática da hiperplasia benigna da próstata (HBP por médicos urologistas da cidade de Porto Alegre. Consistiu em um estudo transversal, exploratório, por meio de entrevista semi-estruturada aplicada a urologistas de Porto Alegre. A amostra foi obtida utilizando catálogo do plano de saúde UNIMED- Porto Alegre. A randomização foi realizada através de sistemática aleatória, sendo sorteados trinta e cinco médicos, dos quais 21 foram selecionados para realização da pesquisa através de questionário. Todos os urologistas entrevistados avaliam e tratam pacientes com hiperplasia benigna da próstata. O saw palmetto não foi citado como terapia medicamentosa de 1ª ou 2ª escolhas no tratamento da HBP. O grupo farmacológico mais freqüentemente utilizado para o tratamento da HBP foi ∝-bloqueadores. Mais da metade dos médicos entrevistados relata ter conhecimento sobre a utilização do saw palmetto, principalmente através de artigos científicos. Os resultados indicam que o saw palmetto não é prescrito pelos urologistas em Porto Alegre, todavia a maior parte destes profissionais tem conhecimento sobre sua utilização.

  6. Tratamiento del agrandamiento gingival por reacción medicamentosa

    OpenAIRE

    Chale Yaringaño, Andrés Rolando

    2017-01-01

    Reporte clínico de un paciente de 61 años de edad de género masculino que acude a la clínica de Postgrado de la UNMSM en el año 2015 por presentar sangrado de encías y problemas estéticos. El caso clínico se resuelve rápidamente con un apropiado manejo de la terapia periodontal, un estricto programa de higiene oral y la colaboración del paciente, no siendo necesario el uso del tratamiento quirúrgico para reducir las lobulaciones de la gíngiva. Trabajo académico

  7. Isolamento e caracterização de fibroblastos gengivais positivos para fosfatase alcalina de pacientes portadores de periodontite crônica e hiperplasia gengival medicamentosa = Isolation and characterization of gingival fibroblasts positive for alkaline phosphatase in patients with chronic periodontitis and drug-induced gingival hyperplasia

    Directory of Open Access Journals (Sweden)

    Santos, Vagner Rodrigues

    2010-01-01

    Full Text Available Objetivo: Investigar a expressão da atividade de fosfatase alcalina (ALP em fibroblastos gengivais de sujeitos com periodontite crônica (PC e hiperplasia gengival medicamentosa (HGM induzida por difenilhidantoína. Metodologia: Os fragmentos gengivais foram obtidos de 13 pacientes (8 mulheres e 5 homens, 22 a 74 anos, sendo 4 fragmentos procedentes de gengiva clinicamente normal (GN, 5 de biópsias de bolsas periodontais com PC e 4 de HGM induzida pela difenilhidantoína. Através de digestão enzimática, suspensões de células gengivais foram preparadas contendo fibroblastos ALP-positivos sem afetar a atividade da enzima ALP. Análises citoquímica e histoquímica foram realizadas. Resultados: Fibroblastos de GN apresentaram fraca positividade para ALP quando comparados com PC e HGM. PC e HGM exibiram níveis elevados e intermediários, respectivamente, de ALP. Observou-se menor proliferação celular na cultura de células em PC e HGM que em GN. Entretanto, a quantidade de células recuperadas das sub-culturas foi similar à quantidade recuperada na cultura inicial para as três linhagens. Conclusões: A expressão de ALP na PC e na HGM encontra-se aumentada e ocorre baixa proliferação de fibroblastos na PC e na HGM. Isto sugere que a inflamação periodontal e a difenilhidantoína podem influenciar a expressão de ALP e a multiplicação de fibroblastos gengivais humanos. Outros estudos são necessários para melhor avaliar a importância de ALP no desenvolvimento e na progressão de PC e HGM

  8. Tratamiento de agrandamiento gingival inducido por fenitoina asociado a placa bacteriana

    Directory of Open Access Journals (Sweden)

    Carmen Julia Rovira

    2013-10-01

    Full Text Available ResumenLa ingesta de algunos medicamentos puede producir un sobre crecimiento de las encías. Se reportan medicamentos tales como los bloqueadores de los canales de calcio, inmunosupresores, anticonvulsivantes que producen estos efectos adversos. Múltiples casos de agrandamientos gingivales están asociados a la ingesta de Fenitoína. El tratamiento de los agrandamientos gingivales inducidos por drogas por lo general es quirúrgico, pero mantener un buen control de placa bacteriana puede evitar en muchos casos que se presente un exagerado aumento de volumen gingival. Se presenta un caso de agrandamiento gingival en paciente masculino de 22 años de edad, bajo tratamiento antiepiléptico con fenitoína. Al examen clínico se observó aumento del volumen gingival de forma generalizada, en maxilar superior e inferior, predominante en sector anterior, produciendo ardor y sangrado durante el cepillado y la ingestión de alimentos. Al sondaje presenta múltiples pseudobolsas en los diferentes cuadrantes. La radiografía panorámica reveló pérdida ósea moderada horizontal, predominante en el sector posterosuperior, posteroinferior y anteroinferior. El plan de tratamiento consistió en fase higiénica, instrucción y motivación en higiene oral a la madre, gingivectomía y gingivoplastía en ambos maxilares. (DUAZARY 2011 No. 2, 226 - 231Abstract The importance of endodontic treatment is to achieve a complete filling and sealing of the root canal to prevent the transport of contaminants to and from root canal, with materials compatible with the surrounding tissues. Occasionally a situation may arise in which the purpose of the maintenance of working length is compromised such as overenlargement. This situation allows the extrusion of filling materials, mainly sealer cements, causing post treatment complications such as inflammatory reactions, injury to adjacent structures (orbital pain, inferior alveolar nerve injury, headache, etc., and infections

  9. Función medular adrenal en pacientes con hiperplasia suprarrenal congénita por déficit de 21-hidroxilasa

    OpenAIRE

    Echeverría Fernández, Maite

    2011-01-01

    La glándula suprarrenal esta formada por dos tejidos endocrinos de diferente origen embriológico: las células de la corteza productoras de esteroides procedentes del mesodermo, y las células cromafines productoras de catecolaminas procedentes de las células de la cresta neural. Clásicamente se ha considerado que la corteza y la medula forman dos unidades endocrinas claramente diferenciadas y separadas. Sin embargo, estos dos sistemas están íntimamente relacionados, tanto ontogénica y anató...

  10. Níquel en cavidad oral de individuos con agrandamiento gingival inducido por tratamiento ortodóncico

    OpenAIRE

    Gómez Arcila, Verónica; Mercado Camargo, Jairo; Herrera Herrera, Alejandra; Fang Mercado,Luis; Díaz Caballero,Antonio

    2014-01-01

    El agrandamiento gingival es una de las alteraciones orales generadas por el uso de aparatología ortodóncica fija. Inicialmente fue descrito como producto de la respuesta alérgica del huésped al níquel, y estudios recientes demostraron que este metal induce proliferación fibroblástica. Sin embargo, se desconoce el grado de bioacumulación de este metal en la cavidad oral. El objetivo del presente estudio consistió en cuantificar la concentración de níquel en muestras de saliva, placa dental y ...

  11. Hiperplasia fibroepitelial mamária em felinos: cinco casos

    Directory of Open Access Journals (Sweden)

    Souza Tatiana Mello de

    2002-01-01

    Full Text Available São descritos cinco casos de hiperplasia fibroepitelial mamária em gatas com idades variando entre 10 meses e 11 anos. A principal queixa por ocasião do atendimento era relacionada à tumefação das mamas com evolução clínica entre 3 e 24 semanas. Em duas das gatas, a condição desenvolveu-se após o tratamento com contraceptivos. Macroscopicamente, as tumorações na glândula mamária eram cobertas por pele, ocasionalmente ulceradas, e tinham superfície de corte brancacenta com nódulos multifocais mais pálidos de 2mm de diâmetro. Histologicamente, esses nódulos multifocais consistiam de proliferação ductal cercadas por crescimento abundante de tecido conjuntivo fibroso.

  12. Hiperplasia Fibrosa Inflamatoria: reporte de un caso Inflammatory Fibrous Hyperplasia: case report

    Directory of Open Access Journals (Sweden)

    A Casian Romero

    2011-08-01

    Full Text Available Introducción: La Hiperplasia Fibrosa Inflamatoria es una alteración caracterizada por un agrandamiento del tejido conectivo; se considera una lesión reactiva ya que se presenta como respuesta a una irritante crónico local; es una lesión común en pacientes adolescentes y de edad adulta debido a que su etiología principal se asocia a maloclusión, al uso de aparatología protésica u ortodóntica mal ajustada, así como a la presencia de biofilm. Sin embargo, la población infantil, principalmente en dentición mixta, no está exenta de presentar esta alteración, aunque en menor proporción. Objetivo: Presentar el caso clínico de un paciente en dentición mixta que presenta una Hiperplasia Fibrosa Inflamatoria con el fin de presentar las características clínicas e histopatológicas de la lesión, enfatizando la importancia de un temprano y correcto diagnóstico. Presentación del Caso: Paciente masculino de 8 años de edad que se presenta a la clínica por presentar lesiones cariosas y malposición dental. A la exploración se observa un agrandamiento gingival localizado, en el órgano dentario 41. Se decide tomar una biopsia de la lesión para establecer el diagnóstico. Conclusión: Debido a que existen varias lesiones con características clínicas muy similares a las que presentaba el paciente, es necesario conocer los diagnósticos diferenciales, así como realizar el diagnóstico temprano de la lesión para poder llevar a cabo un tratamiento eficaz y adecuado.Introduction: The Inflammatory Fibrous Hyperplasia (IFH is a disorder consisting in a connective tissue overgrowth; it is considered a reactive lesion because it appears in response to a chronic and local irritant; this is a very common oral lesion in adolescents and adults, its etiology is associated with dental malocclusion, use of over-extended prosthetic and orthodontic appliances, and with the presence of biofilm (plaque. Nevertheless, child population, mainly patients

  13. HIPERPLASIA GENGIVAL EM CRIANÇAS: USO DE ANTICONVULSIVANTES E HIGIENE ORAL

    Directory of Open Access Journals (Sweden)

    GUARÉ Renata de Oliveira

    1998-01-01

    Full Text Available A hiperplasia gengival tem sido relatada em pacientes tratados com vários anticonvulsivantes, sendo geralmente associada a presença de placa, inflamação gengival e predisposição genética. As autoras avaliaram, em 117 crianças de 4 a 19 anos do setor escolar da Associação de Assistência à Criança Defeituosa (AACD, o uso de drogas anticonvulsivantes por grupo etário, associando-as com o grau de hiperplasia gengival e de higiene bucal. Das crianças avaliadas, apenas 29,05% (34 crianças utilizavam medicação, sendo que, destas, 8,82% (3 crianças apresentavam hiperplasia gengival. Dentre os três grupos etários analisados, podemos inferir que uma eficiente higienização auxilia no controle e pode influir na presença de hiperplasia gengival

  14. Diferencias histológicas en la encía de niños y adultos jóvenes con gingivitis inducida por biopelícula

    OpenAIRE

    Romero Sánchez, Mario Rafael; Pontificia Universidad Javeriana, Bogotá, Colombia; Colmenares Millán, María Marcela; Pontificia Universidad Javeriana, Bogotá, Colombia; Benítez Melo, Alexandra Paola; Pontificia Universidad Javeriana, Bogotá, Colombia; Baltodano Abarca, Flor Emilia; Pontificia Universidad Javeriana, Bogotá, Colombia; Pacheco Rodríguez, Bernal José; Pontificia Universidad Javeriana, Bogotá, Colombia

    2011-01-01

    Antecedentes: la severidad de la gingivitis en niños es menor que en niños mayores o adultos jóvenes; pero no se ha estudiado histológicamente. Objetivo: comparar las características histomorfológicas en gingivitis inducida por biopelícula en niños y adultos jóvenes, para verificar su asociación con la respuesta gingival inflamatoria. Método: se estudiaron veinte dientes con gingivitis inducida por biopelícula, provenientes de diez pacientes médicamente sanos entre los siete y los diez años d...

  15. Estudio del D-004 sobre la defensa antioxidante endógena en ratas con hiperplasia prostática inducida por inyección de testosterona Study of D-004 on the endogenous antioxidant defence in rats presenting with prostate hyperplasia induced by testosterone injection

    Directory of Open Access Journals (Sweden)

    Yohani Pérez Guerra

    2010-06-01

    Full Text Available La hiperplasia prostática benigna, enfermedad común en hombres mayores de 50 años de edad, se caracteriza por el crecimiento incontrolado de la glándula prostática y la presencia de síntomas del tracto bajo urinario. El estrés oxidativo ha sido recientemente asociado con la causa de esta enfermedad. El D-004, extracto lipídico del fruto de la Roystonea regia, ha mostrado reducir la hiperplasia prostática inducida por testosterona en roedores y producir efectos antioxidantes in vitro e in vivo, pero sus efectos sobre las enzimas del sistema antioxidante endógeno no han sido estudiados. Este trabajo investigó los efectos del tratamiento oral con D-004, durante 14 días, sobre las enzimas superóxido dismutasa y catalasa en ratas con hiperplasia prostática inducida por testosterona. Los animales se distribuyeron en 4 grupos: un control negativo y tres inyectados con testosterona: uno tratado con el vehículo (control positivo y dos con D-004 (400 y 800 mg/kg, respectivamente. Se determinó la capacidad antioxidante total del plasma y las actividades de las enzimas superóxido dismutasa y catalasa en eritocitos lisados y plasma, respectivamente. El tratamiento oral con D-004 (400 y 800 mg/kg previno de modo marcado y significativo el agrandamiento de la próstata inducido con testosterona en ratas, y aumentó significativamente la capacidad antioxidante del plasma y la actividad de la catalasa, sin modificar la actividad de la superóxido dismutasa. Estos resultados sugieren que la actividad antioxidante del D-004 está relacionada, al menos parcialmente, con la estimulación de algunas enzimas del sistema antioxidante endógeno.Benign prostatic hyperplasia, a common disease in men aged over 50 is characterized by uncontrolled growth of prostatic gland and the presence of low urinary tract symptoms. The oxidative stress has been recently associated with the disease cause. The D-004, a lipid extract from Roystonea regia, reduces the

  16. Tratamiento de agrandamiento gingival inducido por fenitoina asociado a placa bacteriana

    OpenAIRE

    Carmen Julia Rovira; Jennifer Orozco Páez; Antonio Díaz Caballero

    2013-01-01

    ResumenLa ingesta de algunos medicamentos puede producir un sobre crecimiento de las encías. Se reportan medicamentos tales como los bloqueadores de los canales de calcio, inmunosupresores, anticonvulsivantes que producen estos efectos adversos. Múltiples casos de agrandamientos gingivales están asociados a la ingesta de Fenitoína. El tratamiento de los agrandamientos gingivales inducidos por drogas por lo general es quirúrgico, pero mantener un buen control de placa bacteriana puede evitar e...

  17. Hiperplasia epitelial focal de la boca en Colombia (Enfermedad de Heck

    Directory of Open Access Journals (Sweden)

    Gerzaín Rodríguez Toro

    1989-12-01

    Full Text Available El estudio de biopsias orales remitidas al INS por médicos y odontólogos en Servicio Social Obligatorio en la Amazonía y la Orinoquía y de especímenes de consulta enviados desde el Chocó, Boyacá y el Quindío, demuestra la amplia difusión de la hiperplasia epitelial focal en Colombia. La entidad tiene predominio notorio en las comunidades indígenas. Las lesiones son pápulas numerosas en las mucosas del labio inferior, los carrillos y los bordes de la lengua, que afectan a menores de 16 años y a algunos adultos.Tienden a evolucionar durante años y son asintomáticas. La histopatología revela hiperplasia epitelial global, anastomosis de las crestas, células mitosoides, vacuolización alta y frecuente binucleación de queratinocitos en la mitad superior del epitelio. Con la técnica de PAP y con M.E. se demuestra antígeno de Papilomavirus en las células malpighianas altas y en las células córneas paraqueratósicas. La HEP debe ser bien reconocida por médicos y odontólogos, principalmente por aquellos que prestan su servicio a comunidades indígenas.

  18. Tratamiento farmacológico en la hiperplasia prostática benigna

    Directory of Open Access Journals (Sweden)

    Yohani Pérez Guerra

    2011-03-01

    Full Text Available La hiperplasia prostática benigna, enfermedad común en hombres a partir de los 50 años de edad, consiste en el crecimiento benigno e incontrolado de la glándula prostática y produce diversos síntomas del tracto bajo urinario. Su agente causal multifactorial involucra fundamentalmente el incremento de la conversión de testosterona en dihidrotestosterona por acción de la 5 a-reductasa prostática, lo cual desencadena eventos que propician el incremento en el tamaño de la próstata (componente estático y el aumento del tono del músculo liso de vejiga y próstata (componente dinámico regulado por los adrenoreceptores (ADR-a1. El tratamiento farmacológico de la hiperplasia prostática benigna incluye los inhibidores de la 5a-reductasa, antagonistas de ADR-a1, su terapia combinada y la fitoterapia. El objetivo del presente trabajo fue presentar los aspectos más relevantes de la farmacología de los fármacos utilizados en el tratamiento de la hiperplasia prostática benigna y brindar elementos de su eficacia, seguridad y tolerabilidad. Para ello, se realizó una reseña de los diferentes fármacos utilizados en el tratamiento de esta afección, los que fueron clasificados de acuerdo con su mecanismo de acción. Se incluyeron productos de origen natural como los extractos lipídicos del Serenoa repens y Pygeum africanum, así como el D-004, extracto lipídico de los frutos de la Roystonea regia, que ejerce efectos beneficiosos sobre los principales factores causales de la hiperplasia prostática benigna, ya que es un inhibidor de la 5 a-reductasa prostática, un antagonista de los ADR-a1, un inhibidor de la 5-lipooxigenasa y tiene acción antioxidante, lo que evidencia un mecanismo multifactorial. Los resultados hasta el presente indican que el D-004 es seguro y bien tolerado.

  19. Hiperplasia linfoide cervical por difenilhidantoína.

    Directory of Open Access Journals (Sweden)

    Daniel Guillen

    1995-04-01

    Full Text Available We present the case of a three year old girl who showed two adverse reactions to DPH, one of them a large cervical lymphatic hyperplasia, which responded to discontinuation of the drug. Laboratory test were normal and histological examination showed non specific adenitis. We discuss this unusual case and the importance of the cervical adenopathy differential diagnosis.

  20. Hiperplasia estromal pseudoangiomatosa de la mama (PASH): presentación de dos casos Pseudoangiomatous stromal hyperplasia

    OpenAIRE

    Marta Machado; Alejandrina Garzón; Verónica Muñoz; Ma. Guadalupe Flores Turk

    2009-01-01

    La hiperplasia estromal pseudoangiomatosa (PASH) es una lesión mamaria benigna infrecuente, que afecta comúnmente a mujeres premenopáusicas y que se presenta como un nódulo único, móvil, de consistencia firme y por lo general unilateral. Hay un sobrecrecimiento benigno de tejido conectivo fibroso de la mama que produce numerosos espacios que semejan estructuras vasculares. En la actualidad, la alternativa diagnóstica la provee la punción biopsia percutánea eco-dirigida o por estereotaxia, la ...

  1. Hiperplasia hipofisaria secundaria a hipotiroidismo primario

    Directory of Open Access Journals (Sweden)

    Oscar Castillo

    2013-01-01

    Full Text Available Paciente mujer de 15 años referida por diagnóstico de hipotiroidismo e hiperprolactinemia, con tratamiento irregular para ambas patologías, quien presentó pérdida de conocimiento en dos oportunidades, motivo por el cual se le indicó resonancia magnética (RM de cerebro, en la cual se evidenció imagen tumoral hipofisaria que desplazaba el quiasma óptico. Se le indicó tratamiento con levotiroxina 50 ug por 1 semana, luego 100 ug diario. Los controles hormonales posteriores mostraron normalización, la RM de control evidenció disminución de tamaño de la imagen tumoral en aproximadamente 3 mm, sin repercusión en las estructuras supraselares o paraselares, con mejoría de cuadro clínico luego del tratamiento de sustitución con hormona tiroidea.

  2. Gingivitis ulceronecrosante aguda

    Directory of Open Access Journals (Sweden)

    Eduardo de la Teja-Ángeles

    2015-11-01

    Full Text Available La gingivitis ulcerativa necrosante, conocida por sus siglas en inglés como GUN (anteriormente se le conocía como enfermedad de Vincent o “boca de trinchera” por afectar a soldados en guerra, es una enfermedad poco frecuente.1-6 Se caracteriza por ser una infección aguda y dolorosa en la que las encías sangran, hay necrosis de las papilas interdentales y ataque al estado general.

  3. Influencia de los parámetros mitocondriales en el agradamiento gingival inducido por ciclosporina y nifedipina: ensayo sobre modelo animal

    OpenAIRE

    Román Malo, Lourdes Victoria

    2016-01-01

    El agrandamiento gingival es una entidad patológica englobada dentro de la clasificación de la enfermedad periodontal. Las causas más comunes son en primer lugar como manifestación secundaria al consumo de fármacos - hidantoínas, ciclosporina y bloqueantes de los canales del calcio – y en segundo lugar, la forma idiopática asociada a un síndrome denominado fibromatosis gingival hereditaria. La clínica de este agrandamiento gingival está bien definida, pero las vías moleculares no quedan de...

  4. Hiperplasia fibrosa inflamatoria y posibles factores asociados en adultos mayores

    OpenAIRE

    Rodríguez Zegarra, Anita F.; Facultad de Estomatología, Universidad Peruana Cayetano Heredia. Lima,; Sacsaquispe-Contreras, Sonia; Facultad de Estomatología, Universidad Peruana Cayetano Heredia. Lima,

    2014-01-01

    El propósito del estudio fue determinar la prevalencia de hiperplasia fibrosa inflamatoria (HFI)asociada al uso de prótesis dental removible y sus factores asociados como: sexo, grado deinstrucción, edad, compromiso sistémico, estado nutricional e higiene oral del sujeto; tipo ytiempo de uso de la prótesis, tamaño y ubicación de la lesión en adultos mayores residentes delAlbergue Central “Ignacia Rodulfo Vda. de Canevaro”. Se evaluaron 91 sujetos mayores de 60años (80,67+7,65), que portaban p...

  5. Desquamative gingivitis mimicking mild gingivitis

    Directory of Open Access Journals (Sweden)

    Shravanthi Raghav Yajamanya

    2016-01-01

    Full Text Available The aim of this report is to diagnose the cause for episodic, shifting type of mild inflammation in the isolated areas of gingiva noted by the patient for 1 year. A 33-year-old female patient presented with a chief complaint of mild pain and occasional burning sensation confined to the gingiva to the Department of Periodontology and Oral Implantology. Clinical presentation of the gingiva was seen to mimic mild form of gingivitis for 1 year, with no noted systemic involvement gingival biopsy was performed. The presence of Tzanck cell was noted along with intraepithelial split pointing toward pemphigus. Thus, the study concludes that thorough and meticulous gingival examination can reveal the picture of underlying systemic alterations and is the key for early diagnosis and prompt treatment.

  6. Desquamative gingivitis mimicking mild gingivitis

    Science.gov (United States)

    Yajamanya, Shravanthi Raghav; Jayaram, Praveen; Chatterjee, Anirban

    2016-01-01

    The aim of this report is to diagnose the cause for episodic, shifting type of mild inflammation in the isolated areas of gingiva noted by the patient for 1 year. A 33-year-old female patient presented with a chief complaint of mild pain and occasional burning sensation confined to the gingiva to the Department of Periodontology and Oral Implantology. Clinical presentation of the gingiva was seen to mimic mild form of gingivitis for 1 year, with no noted systemic involvement gingival biopsy was performed. The presence of Tzanck cell was noted along with intraepithelial split pointing toward pemphigus. Thus, the study concludes that thorough and meticulous gingival examination can reveal the picture of underlying systemic alterations and is the key for early diagnosis and prompt treatment. PMID:29242695

  7. Identificación de mutaciones puntuales del gen de la 21-hidroxilasa en pacientes afectados con hiperplasia suprarrenal congénita.

    OpenAIRE

    Dora Fonseca; Andrés Gutiérrez; Claudia Silva; Mauricio Coll; Gustavo Malo; Camilo Orjuela; Alejandro Giraldo

    2005-01-01

    lntroducción. La hiperplasia suprarrenal congénita es un trastorno autosómico recesivo debido a la inadecuada secreción de cortisol. Mas del 95% de los casos de hiperplasia suprarrenal congénita son causados por defectos del gen de la 21 hidroxilasa, CYP21A2 . Las manifestaciones clínicas incluyen la forma clásica y la forma no clásica. Objetivos. Determinar la frecuencia de las mutaciones puntuales P30L, IVS2-12AIC-G, Del 8pb, I172N, cluster Ex 6, V281L, Q318X, R356W y P453S en pacientes con...

  8. Utilização do laser de CO2 em lesões de hiperplasia gengival de pacientes ortodônticos

    OpenAIRE

    Gama,Sabrina Kívia Correia; Araújo,Telma Martins de; Sousa, Ana Paula Cavalcanti de; Pinheiro,Antonio Luiz Barbosa

    2007-01-01

    p. 54-58 A presença de acessórios nos aparelhos ortodônticos fixos favorece o acúmulo de biofilme bacteriano. Além disso, a negligência com a higiene bucal, por parte dos pacientes, faz com que a hiperplasia gengival ocorra com freqüência. O tratamento desta, além da gengivectomia convencional, pode ser realizado com laser de dióxido de carbono. Por um lado, as vantagens do uso deste laser são: proporcionar uma excelente hemostasia, resultante do vedamento de pequenos vasos ...

  9. [Gingival recessions and orthodontics].

    Science.gov (United States)

    Renkema, A M; Padmos, J A D; de Quincey, G de

    2015-11-01

    Gingival recessions represent the most visible periodontal disease. The prevalence of gingival recessions is high. The root surface is literally exposed to negative influences such as erosion, abrasion, discoloration and decay. Moreover, gingival recessions can affect the quality of life by increased thermal sensitivity and reduced dento-gingival aesthetics. The aetiology of gingival recessions is complex and considered to be multifactorial. In order to prevent the development of gingival recessions during and after orthodontic treatment, several factors should be taken into account, among which maintenance of optimal oral hygiene and respect for the 'biological envelope' are decisive. Once gingival recessions have developed, orthodontic therapy can play a positive role in their treatment.

  10. Hiperplasia paratiroidea ectópica de doble localización, intratiroidea e intratorácica

    Directory of Open Access Journals (Sweden)

    Francisco Avello Canisto

    2013-10-01

    Full Text Available Se presenta el caso de una paciente sometida satisfactoriamente a hemitiroidectomía izquierda por diagnóstico de bocio nodular. El estudio anátomo-patológico de la pieza operatoria informó que el aumento de tamaño del lóbulo tiroideo izquierdo se debía a glándula paratiroides hiperplásica intratiroidea. Con este resultado se solicitó gammagrafía paratiroidea, en la que se encontró un área de captación en la región torácica derecha. Se concluyó que se trató de hiperplasia paratiroidea ectópica de doble localización, intratiroidea e intratorácica.

  11. EFECTO DE Tropaeolum tuberosum FRENTE A LA HIPERPLASIA PROSTÁTICA BENIGNA INDUCIDA EN RATAS HOLTZMAN

    Directory of Open Access Journals (Sweden)

    Gioliana Aire-Artezano

    2013-01-01

    Full Text Available Objetivo: Evaluar el efecto de Tropaeolum tuberosum(mashua frente a la Hiperplasia Prostática Benigna (HPB y compararlo con finasterida. Métodos: Estudio experimental completo. Se emplearon 30 ratas Holtzman macho de 12 semanas de edad, aleatorizadas y divididas en seis gru- pos: grupo blanco; grupo testosterona; grupo finasterida (0.33mg/kg/rata; y tres grupos dosis, dosis 1 (300mg/kg/rata, dosis 2 (500mg/kg/rata y dosis 3 (800mg/kg/rata tratados con Tropaeolum tuberosum. Se realizó una medición basal del volumen prostático mediante una ecografía transabdominal. La inducción de HPB se realizó con enantato de testosterona (0,083mg/Kg/rata en los grupos dosis, finasterida y testosterona, el día uno y siete. Paralelamente, se administró liofilizado de Tropaeolum tuberosum y finasterida durante 21 días. Para el diagnóstico, se realiza- ron estudios por imágenes, anatomopatológicos e histopatológicos. Resultados: El estudio por imágenes, en relación al incremento del volumen prostático,no arrojó diferencia significativa entre dosis 2 y finasterida; mientras que en relación con la ecogenicidad, dosis 3 presentó similitud cualitativa al finasterida. En el estudio anatomopatológico, no hubo diferencia significativa entre el grupo dosis 3 y el grupo finasterida. Histo- patológicamente, dosis 3 se asemejó cuantitativamente al finasterida. Conclusiones: Se evidenció disminución de la HPB histológicamente y en el estudio por imágenes; sin embargo, ninguna de las dosis mostró efecto superior al finasterida.

  12. Evaluación e intervención logopédica en un caso de Hiperplasia Suprarrenal Congénita

    OpenAIRE

    Herrero Galiacho, Ana

    2016-01-01

    El presente trabajo se basa en el estudio de un caso de Hiperplasia Suprarrenal Congénita, realizado durante la asignatura de Practicum III del Grado en Logopedia, en la Unidad Clínica de Logopedia y Foniatría de la Facultad de Medicina, de la Universidad de Valladolid. Se realizará una evaluación inicial completa de todos los niveles lingüísticos y comunicativos que pudieran verse afectados por la alteración, para posteriormente realizar una intervención logopédica adecuada y adaptada a las ...

  13. Hiperplasia angiolinfoide com eosinofilia: um caso raro em cavidade oral

    Directory of Open Access Journals (Sweden)

    Jefferson da Rocha Tenório

    Full Text Available Resumo A hiperplasia angiolinfoide com eosinofilia (HALE é considerada uma lesão vascular benigna rara que acomete, principalmente, o tecido cutâneo e subcutâneo da região de cabeça e pescoço, mas incomum na cavidade oral. Sua etiopatogenia permanece indefinida, sendo descrita como proliferação vascular reacional, malformação vascular ou neoplasia. Tem como principal diagnóstico diferencial a doença de Kimura. Este trabalho relata um caso de um paciente do sexo masculino, de 50 anos, que exibia aumento de volume nodular na mucosa do lábio superior, com 3 cm de dimensão e 7 anos de evolução. Após a biópsia excisional, o exame histopatológico mostrou lesão bem encapsulada multilobulada com proliferação de capilares sanguíneos com células endoteliais de aspecto epitelioide, infiltrado inflamatório difuso com linfócitos, plasmócitos, inúmeros eosinófilos e presença de folículos linfoides. A análise imuno-histoquímica revelou positividade para CD34 e Ki-67, o que, juntamente com o exame morfológico, direcionou o diagnóstico para HALE.

  14. Tratamiento farmacológico en la hiperplasia prostática benigna Pharmacological treatment of the benign prostatic hyperplasia

    Directory of Open Access Journals (Sweden)

    Yohani Pérez Guerra

    2011-03-01

    Full Text Available La hiperplasia prostática benigna, enfermedad común en hombres a partir de los 50 años de edad, consiste en el crecimiento benigno e incontrolado de la glándula prostática y produce diversos síntomas del tracto bajo urinario. Su agente causal multifactorial involucra fundamentalmente el incremento de la conversión de testosterona en dihidrotestosterona por acción de la 5 a-reductasa prostática, lo cual desencadena eventos que propician el incremento en el tamaño de la próstata (componente estático y el aumento del tono del músculo liso de vejiga y próstata (componente dinámico regulado por los adrenoreceptores (ADR-a1. El tratamiento farmacológico de la hiperplasia prostática benigna incluye los inhibidores de la 5a-reductasa, antagonistas de ADR-a1, su terapia combinada y la fitoterapia. El objetivo del presente trabajo fue presentar los aspectos más relevantes de la farmacología de los fármacos utilizados en el tratamiento de la hiperplasia prostática benigna y brindar elementos de su eficacia, seguridad y tolerabilidad. Para ello, se realizó una reseña de los diferentes fármacos utilizados en el tratamiento de esta afección, los que fueron clasificados de acuerdo con su mecanismo de acción. Se incluyeron productos de origen natural como los extractos lipídicos del Serenoa repens y Pygeum africanum, así como el D-004, extracto lipídico de los frutos de la Roystonea regia, que ejerce efectos beneficiosos sobre los principales factores causales de la hiperplasia prostática benigna, ya que es un inhibidor de la 5 a-reductasa prostática, un antagonista de los ADR-a1, un inhibidor de la 5-lipooxigenasa y tiene acción antioxidante, lo que evidencia un mecanismo multifactorial. Los resultados hasta el presente indican que el D-004 es seguro y bien tolerado.Benign prostatic hyperplasia is a common disease in over 50 years-old men consisting in uncontrolled and benign growth of prostatic gland that leads to lower urinary

  15. Treatment of gingival recession.

    Science.gov (United States)

    Kassab, Moawia M; Badawi, Hala; Dentino, Andrew R

    2010-01-01

    Gingival recession is an intriguing and complex phenomenon. Recession frequently disturbs patients because of sensitivity and esthetics. Many surgical techniques have been introduced to treat gingival recession, including those involving autogenous tissue grafting, various flap designs, orthodontics, and guided tissue regeneration. This article describes different clinical approaches to treat gingival recession with emphasis on techniques that show promising results and root coverage.

  16. [Gingival recessions and orthodontics

    NARCIS (Netherlands)

    Renkema, A.M.; Padmos, J.A.; Quincey, G. de

    2015-01-01

    Gingival recessions represent the most visible periodontal disease. The prevalence of gingival recessions is high. The root surface is literally exposed to negative influences such as erosion, abrasion, discoloration and decay. Moreover, gingival recessions can affect the quality of life by

  17. The phylum Synergistetes in gingivitis and necrotizing ulcerative gingivitis

    National Research Council Canada - National Science Library

    Baumgartner, Angelica; Thurnheer, Thomas; Lüthi-Schaller, Helga; Gmür, Rudolf; Belibasakis, Georgios N

    2012-01-01

    The clinical manifestation of necrotizing ulcerative gingivitis (NUG) is distinct from that of common gingivitis in that it is characterized by local necrosis of the gingival tissues, rapid onset, pain and extensive bleeding...

  18. Gingival tissue transcriptomes in experimental gingivitis

    Science.gov (United States)

    Jönsson, Daniel; Ramberg, Per; Demmer, Ryan T.; Kebschull, Moritz; Dahlén, Gunnar; Papapanou, Panos N.

    2012-01-01

    Aims We investigated the sequential gene expression in the gingiva during the induction and resolution of experimental gingivitis. Methods Twenty periodontally and systemically healthy non-smoking volunteers participated in a 3-week experimental gingivitis protocol, followed by debridement and 2-week regular plaque control. We recorded clinical indices and harvested gingival tissue samples from 4 interproximal palatal sites in half of the participants at baseline, Day 7, 14 and 21 (‘induction phase’), and at day 21, 25, 30 and 35 in the other half (‘resolution phase’). RNA was extracted, amplified, reversed transcribed, amplified, labeled and hybridized with Affymetrix Human Genome U133Plus2.0 microarrays. Paired t-tests compared gene expression changes between consecutive time points. Gene ontology analyses summarized the expression patterns into biologically relevant categories. Results The median gingival index was 0 at baseline, 2 at Day 21 and 1 at Day 35. Differential gene regulation peaked during the third week of induction and the first four days of resolution. Leukocyte transmigration, cell adhesion and antigen processing/presentation were the top differentially regulated pathways. Conclusions Transcriptomic studies enhance our understanding of the pathobiology of the reversible inflammatory gingival lesion and provide a detailed account of the dynamic tissue responses during induction and resolution of experimental gingivitis. PMID:21501207

  19. Necrotizing ulcerative gingivitis

    OpenAIRE

    Rayhana Malek; Amina Gharibi; Nadia Khlil; Jamila Kissa

    2017-01-01

    Necrotizing ulcerative gingivitis (NUG) is a typical form of periodontal diseases. It has an acute clinical presentation with the distinctive characteristics of rapid onset of interdental gingival necrosis, gingival pain, bleeding, and halitosis. Systemic symptoms such as lymphadenopathy and malaise could be also found. There are various predisposing factors such as stress, nutritional deficiencies, and immune system dysfunctions, especially, HIV infection that seems to play a major role in t...

  20. Tratamento Clínico e Seguimento das Hiperplasias de Endométrio Clinical Treatment and Follow-up of Endometrial Hyperplasia

    Directory of Open Access Journals (Sweden)

    Anaglória Pontes

    2000-01-01

    Full Text Available Objetivos: avaliar a eficácia do acetato de medroxiprogesterona e do acetato de megestrol nas hiperplasias de endométrio. Métodos: foram incluídas, retrospectivamente 47 pacientes com sangramento uterino anormal, submetidas a curetagem uterina diagnóstica e/ou biópsia de endométrio, cujo achado histopatológico foi de hiperplasia de endométrio. Nas pacientes com hiperplasia sem atipia foi iniciado a terapêutica com acetato de medroxiprogesterona por via oral, na dose de 10 mg/dia durante 10-12 dias por mês. Nas com atipia, era utilizado o acetato de megestrol por via oral, dose de 160 mg/dia, uso contínuo. O período de tratamento variou de 3 a 18 meses. Biópsia de endométrio e/ou curetagem uterina de controle foram realizadas entre três e seis meses do início do tratamento e periodicamente para avaliar a resposta terapêutica. Resultados: foram analisadas 42 pacientes com hiperplasia endometrial sem atipia e cinco com atipia. A média de idade das pacientes foi de 49,5 ± 10,6 anos, sendo 70,2% com idade superior a 45 anos. O acetato de medroxiprogesterona foi eficaz em fazer regredir as hiperplasias sem atipias em 83,2% (35/42 e o acetato de megestrol em 80% (4/5 das hiperplasias com atipia. Em 16,8% (7 casos das hiperplasias sem atipia e em 20% (1 caso das com atipia, ocorreu persistência das lesões, apesar do tratamento. Em nenhum caso ocorreu progressão para câncer de endométrio, durante o período de seguimento que foi de 3 meses a 9 anos. No acompanhamento dessas pacientes, verificamos que 18 (38,3% apresentaram amenorréia, em 12 (25,5% ocorreu regularização do ciclo menstrual e 17 (36,2% permaneceram com sangramento uterino anormal, sendo submetidas a histerectomia total abdominal. O exame anatomopatológico mostrou a persistência da lesão hiperplásica em oito casos, leiomioma em quatro, adenomiose em três, mio-hipertrofia uterina difusa em um caso e útero normal em outro, tendo havido regressão das les

  1. Tatuagem extensa por amálgama em mucosa gêngivo-alveolar Extensive amalgam tattoo on the alveolar-gingival mucosa

    Directory of Open Access Journals (Sweden)

    Vivian C Galletta

    2011-10-01

    Full Text Available Tatuagens por amálgama são lesões pigmentadas, exógenas, de frequente ocorrência na mucosa bucal, que resultam da introdução acidental de partículas de amálgama nos tecidos moles. O diagnóstico da tatuagem por amálgama é simples, geralmente, baseado em achados clínicos, complementado pela história recente ou pregressa de remoção de restauração por amálgama. Radiografias intraorais podem ser úteis na detecção de radiopacidade, associadas à partícula de amálgama. Nos casos em que as tatuagens por amálgama não permitem diferenciação de outras lesões melanocíticas, o exame histopatológico deve ser realizado. Os autores relatam à ocorrência de lesão extensa por tatuagem de amálgama com confirmação histopatológica.Amalgam tattoos are common exogenous pigmented lesions of the oral mucosa occurring mainly by inadvertent placement of amalgam particles into soft tissues. The diagnosis of amalgam tattoo is simple, usually based on clinical findings associated with presence or history of amalgam fillings removal. Intraoral X-rays may be helpful in detecting amalgam-related radiopacity. In cases where amalgam tattoo cannot be differentiated from other causes of oral pigmentation, a biopsy should be performed. This article deals with an extensive amalgam tattoo lesion which required a biopsy for a definitive diagnosis.

  2. Processos proliferativos gengivais não neoplásicos em paciente sob tratamento ortodôntico Non-neoplastic proliferative gingival processes in patients undergoing orthodontic treatment

    Directory of Open Access Journals (Sweden)

    Irineu Gregnanin Pedron

    2010-12-01

    Full Text Available INTRODUÇÃO: a aparatologia ortodôntica dificulta a higiene bucal e pode contribuir para a formação de lesões gengivais, como os processos proliferativos gengivais não neoplásicos. Essas lesões, dependendo de alguns fatores - como o tempo de evolução, constituintes histopatológicos e condições bucais -, podem ser reversíveis, em alguns casos, por meio da orientação sobre higiene bucal e da terapia periodontal básica. Entretanto, na maioria das vezes há necessidade de tratamento cirúrgico. OBJETIVO: o propósito deste trabalho é relatar o caso de uma paciente portadora de aparatologia ortodôntica fixa que apresentou duas lesões gengivais distintas, diagnosticadas como granuloma piogênico e hiperplasia gengival inflamatória. Foram discutidas as características clínicas e histopatológicas, incidência e frequência, modalidades terapêuticas e prevenção de ambas as lesões, demonstrando a importância do encaminhamento do material colhido ao exame histopatológico, dada a possibilidade de diversas hipóteses diagnósticas. Em ambas as lesões foi realizada a exérese cirúrgica. RESULTADOS: a lesão na arcada superior, diagnosticada como granuloma piogênico, apresentou recorrência, sendo necessária terapia periodontal básicae repetiçãodoprocedimento cirúrgico. Alesão na arcada inferior foi diagnosticada como hiperplasia gengival, sendo removida cirurgicamente e acompanhada clinicamente, com prescrição de orientação da higiene bucal ao pacienteINTRODUCTION: Orthodontic appliances render oral hygiene difficult and may contribute to the development of gingival lesions such as non-neoplastic proliferative gingival processes. These lesions, depending on such factors as development time, histopathological components and oral conditions may be reversible in some cases - through oral hygiene advice and basic periodontal therapy. In most cases, however, surgical treatment is required. OBJECTIVES: The purpose of this

  3. Corticoterapia profiláctica transquirúrgica de la hiperplasia cicatricial: estudio clínico-estadístico prospectivo

    Directory of Open Access Journals (Sweden)

    César-Kelly Villafuerte-Vélez

    Full Text Available Antecedentes y Objetivo: La hiperplasia cicatricial, denominación que reúne la cicatriz hipertrofica y el queloide, representa un gran desafio en la práctica quirúrgica. Estas patologías que solo acometen a los seres humanos, y en especial el queloide, se han asociado a las razas negra y amarilla, hecho corroborado en el estado de Bahía - Brasil, donde la afro-descendencia es muy significativa y donde gran número de mamoplastias de reducción se acompañan de hiperplasia cicatricial. Son anomalías que generan mucha insatisfacción en los pacientes y en los cirujanos. El objetivo del presente estudio es demostrar que se pueden prevenir este tipo de cicatrices antes de la incisión cutánea y antes del disparo de la cascada de reparación, moldeando las fases iniciales de la cicatrización con el uso de un corticoide especifico. Material y método. Planteamos un estudio prospectivo de prevalencia longitudinal y autocontrolado, en 60 mamas de 30 mujeres con diagnóstico de gigantomastia, a las que se les practicó mamoplastia de reducción en T invertida e injerto de placa areola-papilar (Thorek-Pitanguy, comparando 2 grupos: el primero con 30 mamas derechas infiltradas con solución de corticoide antiquimiotáxico en dermis y subcutáneo, por debajo de la tinta del diseño de la marcación prequirúrgica y antes de las incisiones; y el segundo con 30 mamas izquierdas sin infiltración (grupo control, para determinar estadísticamente, después de un periodo de seguimiento, la eficacia profiláctica del acetato de dexametasona en la prevención de la hiperplasia cicatricial. Tras un seguimiento postoperatorio de 6 a 15 meses, clasificamos el tipo de cicatrización obtenido según la escala de Vancouver, con documentación fotográfica. Realizamos los estudios estadísticos con test de Chi-cuadrado y prueba de Kruskal-Wallis para análisis experimental. Resultados. Comprobamos una disminución estadísticamente significativa al comparar la

  4. HIPERPLASIA ADRENAL KONGENITAL (HAK KLASIK SIMPLE VIRILIZING PADA ANAK UMUR 3 TAHUN

    Directory of Open Access Journals (Sweden)

    Alice Indradjaja

    2015-01-01

    Full Text Available Hiperplasia adrenal kongenital merupakan salah satu dari kelompok kelainan genetik akibat defisiensi enzim yang diperlukan untuk biosintesis steroid di korteks kelenjar adrenal. Bentuk kelainan hiperplasia adrenal kongenital yang tersering adalah defisiensi enzim 21-hidroksilase (21OHD hingga mencapai 90% kasus. Kelainan utama pada pasien dengan defisiensi enzim 21-hidroksilase adalah kegagalan sintesis kortisol secara adekuat. Defisiensi 21-hidroksilase klasik tipe virilisasi sederhana menyebabkan genitalia ambigu pada bayi perempuan. Dilaporkan sebuah kasus hiperplasia adrenal kongenital klasik tipe virilisasi sederhana pada anak perempuan usia tiga tahun. Pasien dirujuk ke Poliklinik anak RSUP Sanglah Denpasar dengan keluhan utama pembesaran dan pemanjangan klitoris yang progresif disertai tumbuhnya bulu pubis.  Pasien lahir dengan genitalia ambigu. Pasien didiagnosis defisiensi 21-hidroksilase berdasarkan hasil pemeriksaan kadar progesteron 17-OH >1.200ng/dl dan pemeriksaan fisik didapatkan prader derajat III. Pada pemeriksaan usia tulang menunjukkan usia tulang yang melebihi umurnya, USG abdomen dalam batas normal dengan hasil analisis kromosom 46,XX. Pasien tidak pernah mengalami krisis adrenal selama 3 tahun dan menjalani tindakan pembedahan pada usia 3 tahun. Keluarga pasien diberikan konseling, dilakukan monitor  berkala pada pasien dan terapi hidrokortison. Prognosis pada pasien ini baik. [MEDICINA 2014;45:58-64].

  5. Hiperplasia estromal pseudoangiomatosa de la mama (PASH: presentación de dos casos Pseudoangiomatous stromal hyperplasia

    Directory of Open Access Journals (Sweden)

    Marta Machado

    2009-12-01

    Full Text Available La hiperplasia estromal pseudoangiomatosa (PASH es una lesión mamaria benigna infrecuente, que afecta comúnmente a mujeres premenopáusicas y que se presenta como un nódulo único, móvil, de consistencia firme y por lo general unilateral. Hay un sobrecrecimiento benigno de tejido conectivo fibroso de la mama que produce numerosos espacios que semejan estructuras vasculares. En la actualidad, la alternativa diagnóstica la provee la punción biopsia percutánea eco-dirigida o por estereotaxia, la que permite determinar la naturaleza de la lesión y descartar patología maligna, como el angiosarcoma, a fin de evitar la realización de biopsias quirúrgicas innecesarias. Presentamos dos casos que fueron categorizados en el control inicial por mamografía como BI-RADS 4c, lo que determinó la realización de una punción biopsia.Pseudoangiomatous stromal hyperplasia (PASH is a rare benign breast lesion, which commonly affects premenopausal women. It occurs as a single node, which is mobile, firm and usually unilateral. PASH is characterized by a benign overgrowth of fibrous connective tissue of the breast, which produces numerous spaces resembling vascular structures. The diagnostic alternative is currently provided by the ultrasound guided percutaneous biopsy or stereotactic biopsy, which determines the nature of the lesion and rules out malignancy, such as angiosarcoma, in order to avoid unnecessary surgical biopsies. We present two lesions that were classified as BI-RADS 4c in the initial control by mammography, which led to a needle biopsy.

  6. Gingival Recessions and Biomechanics

    DEFF Research Database (Denmark)

    Laursen, Morten Godtfredsen

    Gingival recessions and biomechanics “Tissue is the issue, but bone sets the tone.“ A tooth outside the cortical plate can result in loss of bone and development of a gingival recession. The presentation aims to show biomechanical considerations in relation to movement of teeth with gingival...... by moving the root back in the alveolus. The tooth movement is accompanied by bone gain and thus increase the success rate for soft tissue augmentation. The choice of biomechanical system influences the treatment outcome. If a standard straight wire appliance is used, a biomechanical dilemma can arise...

  7. Modelos experimentais de hiperplasia intimal: efeitos da radiação ionizante

    Directory of Open Access Journals (Sweden)

    Regina de Faria Bittencourt da Costa

    2002-05-01

    Full Text Available A hiperplasia intimal ocorre em resposta à lesão vascular, pode complicar significantemente os procedimentos vasculares abertos e endovasculares, levando a diferentes graus de estenose do lume vascular e isquemia. De certo modo, a hiperplasia intimal está presente em todos os tipos de reconstruções vasculares, incluindo enxertos autólogos, homólogos e sintéticos, após angioplastias com ou sem colocação de stent e em órgãos transplantados. Um dos maiores desenvolvimentos experimentais nos últimos anos, para prevenção da hiperplasia intimal, é a utilização da radiação ionizante. A radiação ionizante inibe a proliferação de muitos tipos celulares, incluindo fibroblastos e células musculares lisas in vitro e a síntese de colágeno em culturas de fibroblastos. Modelos animais de experimentação têm sido utilizados para o desenvolvimento de novas estratégias de tratamento e entendimento dos mecanismos fisiopatológicos básicos da hiperplasia intimal. Assim, o objetivo desta revisão e atualização da literatura é o de expor os diferentes modelos de animais de experimentação para o desenvolvimento de hiperplasia intimal, o tipo de lesão empregada, as artérias mais utilizadas e os efeitos encontrados com o uso de diferentes tipos de fontes de radiação ionizante.Most complications that may occur in response to vascular injury of endovascular and open vascular procedures are due to intimal hyperplasia. To a certain extent, intimal hyperplasia is present in all types of vascular reconstruction, including autologous grafts, allografts, and prosthetic grafts found in solid organs transplanted, having a substantial role in chronic rejection and following angioplasty with or without stenting. One of the greatest developments in recent years towards prevention of intimal hyperplasia is the use of ionizing radiation. Ionizing radiation inhibits proliferation of many cell types including fibroblasts and smooth muscle cells

  8. Alteraciones neuropsicológicas en la hiperplasia adrenal congénita Neuropsychological disorders related to congenital adrenal hyperplasia

    Directory of Open Access Journals (Sweden)

    Yaser Ramírez Benítez

    2008-12-01

    Full Text Available INTRODUCCIÓN: la hiperplasia adrenal congénita engloba un conjunto de enfermedades genéticas de transmisión autosómica recesiva caracterizadas por un trastorno de la esteroidogénesis suprarrenal. Constituye un caso típico de daño cerebral por el efecto patológico de las hormonas sexuales en el sistema nervioso en desarrollo, y a esto se le suman las secuelas secundarias al cuadro grave de crisis adrenal que aparece en la forma clásica a los pocos días de vida. MÉTODOS: estudio de caso en un niño de 6 años de edad con antecedentes de hiperplasia adrenal congénita perdedora de sal. Se determinaron los puntos débiles y fuertes en el desarrollo a través de la batería neuropsicológica Luria Inicial. Como complementario a la evaluación se aplicó la Escala de Inteligencia de Weschler y el Cuestionario de Comportamiento Infantil para padres y profesores. RESULTADOS: el niño presenta un perfil neuropsicológico caracterizado por bajas puntuaciones en: motricidad manual, habilidades viso-espaciales, impulsividad, pobre vocabulario, dificultades en operaciones de cálculos sencillos, en el reconocimiento de objetos por el tacto sin la ayuda visual y en la rapidez de procesamiento. La capacidad de inteligencia está en límites normales con un rendimiento más bajo en la escala no verbal. En la escala de comportamiento se identificaron las dificultades en la atención y en el aprendizaje. CONCLUSIONES: el perfil neuropsicológico se caracteriza por tener bajas ejecuciones en tareas verbales, no verbales y en la velocidad de procesamiento. El tratamiento hormonal en los primeros días de nacido permite que el desarrollo siga un curso "normal", pero todo proceso tiene un costo que se refleja en la adquisición de habilidades psicológicas superioresCongenital adrenal hyperplasia includes a series of genetic diseases of autosomal recessive transmission characterized by a disorder of suprarenal esteroidogenesis. This is a typical case of

  9. Evidencia molecular y serológica de la asociación del PVH-13 con la hiperplasia epitelial focal en la comunidad indígena embera-chami de Jardín, Antioquia-Colombia

    OpenAIRE

    Juan Alberto Pérez; César Julián López; Correa, Luis A.; Viviana Cuberos; Angela Gaviria; Leonor Victoria González; Gloria Sanclemente; Gloria Inés Sánchez

    2004-01-01

    Introducción: La hiperplasia epitelial focal (HEF) o enfermedad de Heck es una entidad benigna de la mucosa oral que se presenta principalmente en jóvenes de grupos étnicos muy específicos. Aunque el epónimo de “Enfermedad de Heck” proviene del primer caso reportado en 1961 por el Dr. Heck en Nuevo Méjico, ya previamente en Colombia el Dr. Estrada en 1956 había reportado esta entidad en los indios Caramanta (1)...

  10. Hallazgo de una hiperplasia lipomatosa del septum interauricular en un caso de muerte súbita Finding of a lipomatous hyperplasia in the interatrial septum in a case of sudden death

    OpenAIRE

    Sánchez-Quintana, D; Murillo, M.; F. Sánchez-Ugena; S. Alama; Merino, M. J.; M.T. Sánchez

    2011-01-01

    La hiperplasia lipomatosa del septum interauricular (HLSI) es una entidad benigna de naturaleza desconocida que se caracteriza por la acumulación de grasa no encapsulada en el interior del surco interauricular sin participación de la fosa oval. A pesar de su carácter benigno, clínicamente se ha asociado con arritmias cardiacas, generalmente de origen supraventricular, insuficiencia cardiaca y muerte súbita. Presentamos el caso de una mujer de edad media (47 años), con obesidad mórbida e insuf...

  11. Efecto diferencial de Lepidium meyenii (Maca roja) y finasteride sobre los procesos inflamatorios en la hiperplasia prostática benigna inducida con enantato de testosterona en ratas de la cepa Holtzman

    OpenAIRE

    Gasco Tantachuco, Manuel Enrique

    2014-01-01

    El objetivo central de esta tesis fue evaluar si existen mecanismos de acción diferenciales en próstata (P) y vesículas seminales (VS) del extracto hidroalcohólico atomizado de maca roja (MR) y el finasteride (F) en ratas inducidas a Hiperplasia Prostática Benigna (HPB) ocasionado por el enantato de testosterona (ET). Se formaron 5 grupos de animales, un grupo control, con ET, con ET más F y dos grupos con ET más MR. Luego de los tratamientos se evaluaron las citoquinas: TNF-α, IL-4 e INF-γe...

  12. Papilomavirus Humanos con Hiperplasia Epitelial Focal en la Población escolar indígena Embera-Chamí de Cristianía, municipio de Jardín, Antioquia

    Directory of Open Access Journals (Sweden)

    Gloria Inés Sánchez

    2001-04-01

    Full Text Available

    La Hiperplasia Epitelial Focal (HEF o enfermedad de Heck es una enfermedad de la mucosa oral, con alta prevalencia entre comunidades indígenas. Esta enfermedad ha sido relacionada con
    Papilomavirus humanos (PVH genotipos 13 y 32. Anteriormente se
    encontró una alta prevalencia de esta enfermedad entre la comunidad indígena Embera-Chamí del municipio de Antioquia (1. El objetivo de este estudio fue establecer la asociación entre la infección por PVH y el desarrollo de HEF en esta comunidad.

     

     

  13. Avaliação comparativa da morfologia condilar entre pacientes com hiperplasia condilar unilateral e com deformidade dentofacial Classe III = Comparative evaluation of condylar morphology between patients with unilateral condylar hyperplasia and Class III dentofacial deformity : Comparative evaluation of condylar morphology between patients with unilateral condylar hyperplasia and class III dentofacial deformity

    OpenAIRE

    Douglas Rangel Goulart

    2015-01-01

    Resumo: O objetivo deste estudo foi comparar a morfologia condilar de pacientes com hiperplasia condilar unilateral e pacientes com deformidade dentofacial Classe III por meio de tomografia computadorizada de feixe cônico (TCFC). Foram realizados dois estudos independentes, o primeiro com pacientes que procuraram o Departamento de Cirurgia Oral e Maxilofacial da Universidad de La Frontera - Chile, para tratamento de deformidade e assimetria facial. Foram selecionados 30 pacientes, 15 com HC e...

  14. Gingival Cyst of Newborn.

    Science.gov (United States)

    Moda, Aman

    2011-01-01

    Gingival cyst of newborn is an oral mucosal lesion of transient nature. Although it is very common lesion within 3 to 6 weeks of birth, it is very rare to visualize the lesion thereafter. Presented here is a case report of gingival cyst, which was visible just after 15 days of birth. Clinical diagnoses of these conditions are important in order to avoid unnecessary therapeutic procedure and provide suitable information to parents about the nature of the lesion.

  15. Identificación de mutaciones puntuales del gen de la 21-hidroxilasa en pacientes afectados con hiperplasia suprarrenal congénita.

    Directory of Open Access Journals (Sweden)

    Dora Fonseca

    2005-06-01

    Full Text Available lntroducción. La hiperplasia suprarrenal congénita es un trastorno autosómico recesivo debido a la inadecuada secreción de cortisol. Mas del 95% de los casos de hiperplasia suprarrenal congénita son causados por defectos del gen de la 21 hidroxilasa, CYP21A2 . Las manifestaciones clínicas incluyen la forma clásica y la forma no clásica. Objetivos. Determinar la frecuencia de las mutaciones puntuales P30L, IVS2-12AIC-G, Del 8pb, I172N, cluster Ex 6, V281L, Q318X, R356W y P453S en pacientes con hiperplasia suprarrenal congénita. Materiales y métodos. Se estudiaron 58 pacientes, de los cuales, 48 fueron clásicos y 10 no clásicos. Mediante PCR alelo-especifica y ACRS (Amplified Creation Restriction Sites, se analizaron 9 mutaciones puntuales del gen CYP21A2 y se determinó la frecuencia en la población analizada. Resultados. Los alelos afectados se identificaron en el 82,8% de los cromosomas. Las mutaciones mas frecuentes fueron: IVS2-12AIC-G (26,7%, Q318X (21,5%, V281L (12,1% e I172N (12,1%. Conclusiones. Las mutaciones mas frecuentes en Colombia son similares a las de otros países del mundo, excepto para Q318X que presentó una mayor frecuencia, pero similar a la de otros países latinoamericanos. Este hallazgo y la existencia de 17,2% de alelos no identificados puede indicar diferencia entre el acervo genético de las poblaciones. En la forma clásica perdedora de sal predominaron las mutaciones Q318X e IVS2-12AIC-G; en la virilizante simple, IVS2-12AIC-G e I172N y en la no clásica , V281L, lo cual esta relacionado con el grado de actividad enzimática. En la forma no clásica, se encontraron alelos severos en el 66,7% de los casos, lo que determina el riesgo de tener hijos afectados con la forma grave virilizante simple o perdedora de sal. Los resultados reportados permiten ofrecer asesoramiento genético y diagnóstico prenatal.

  16. Plasma cell gingivitis

    Directory of Open Access Journals (Sweden)

    Chandershekhar Joshi

    2015-01-01

    Full Text Available The aim of the article is to present a report on the clinical presentation of plasma cell gingivitis with the use of herbal toothpowder. Plasma cell gingivitis [PCG] is a rare benign condition of the gingiva characterized by sharply demarcated erythematous and edematous gingivitis often extending to the mucogingival junction. As the name suggests it is diffuse and massive infiltration of plasma cells into the sub-epithelial gingival tissue. It is a hypersensitivity reaction to some antigen, often flavouring agents or spices found in chewing gums, toothpastes and lorenzes. A 27-yr old male with a chief complaint of painful, bleeding swollen mass in his lower front teeth region with prolong use of herbal toothpowder.The gingiva bled readily on probing. Patient was advised to refrain from the use of herbal toothpowder and along with periodontal treatment, no further reoccurrence was found. as more and more herbal products are gaining popularity, clinicians should be aware of effects of these products. Early diagnosis is essential as plasma cell gingivitis has similar pathologic changes seen clinically as in leukemia, HIV infection, discoid lupus erythematosis, atrophic lichen planus, desquamative gingivitis, or cicatrical pemphigoid which must be differentiated through hematologic and serologic testing.

  17. Hiperplasia linfóide angiofolicular - Doença de Castleman - do mediastino: Apresentação de um caso clínico Mediastinal angiofolicular lymphoid hyperplasia - Castleman’s disease: Case report

    Directory of Open Access Journals (Sweden)

    Vitor Sousa

    2006-05-01

    Full Text Available A hiperplasia linfóide angiofolicular foi inicialmente descrita por Castleman como uma hiperplasia do gânglio linfático, caracterizada por folículos anormais, com centros germinativos pequenos e marcada proliferação capilar. Os autores apresentam o caso de um homem de 37 anos com toracalgia e massa mediastínica com 4 cm de diâmetro, constituída por tecido vermelho-escuro e carnudo, com pequena área central branca. Foi diagnosticada a variante plasmocitária da hiperplasia infóide angiofolicular em gânglio linfático mediastínico. Apresentava mais dois gânglios "diafragmáticos" envolvidos pela mesma doença. A hiperplasia linfóide angiofolicular, ou doença de Castleman, é uma doença linfoproliferativa rara que atinge frequentemente o mediastino ou os gânglios linfáticos do hilo pulmonar. Pode ter, no entanto, outras localizações, na forma multisistémica. Estão descritas duas variantes morfológicas: a vascular hialina e a plasmocitária. A IL-6 parece ter um papel importante na sua patogenia, quando se trata da variante plasmocitária. A doença de Castleman deve ser considerada no diagnóstico diferencial de massas mediastínicas, nomeadamente com linfomas.Angiofolicular lymphoid hyperplasia was first described by Castleman as a lymph node hyperplasia characterized by abnormal follicles with small germinal centres and high capillary proliferation. The authors present a case of a 37 year old man with thoracalgy and a mediastinal mass of 4 cm diameter, fleshy and red with a white central area. The diagnosis of plasma cell type of angiofolicular lymphoid hyperplasia in an mediastinal lymph node was made. He also had involvement of two "diaphragmatic" lymph nodes. Angiofolicular lymphoid hyperplasia - Castleman’s disease - is a rare lymphoproliferative disease that involves the mediastine or the pulmonary hilus when of solitary form but it can also have other localizations (multicentric or systemic form. Two histological

  18. Reconstrucción genital integral en la Hiperplasia Suprarrenal Congénita: sensibilidad, estética y función (embarazo

    Directory of Open Access Journals (Sweden)

    A.A. Núñez Serrano

    Full Text Available La Hiperplasia Suprarrenal Congénita o Síndrome Adrenogenital es un cuadro clínico poco frecuente. Las anomalías que presenta van asociadas a síndromes que a veces son muy complejos, destacando, entre otros, el seudohermafroditismo femenino y el hermafroditismo verdadero. Las mujeres que la padecen presentan como alteración más evidente un clítoris aumentado de tamaño (megaloclítoris y otras alteraciones en los genitales externos. Ante estas pacientes es necesario realizar un diagnostico correcto mediante exploración física y otras pruebas complementarias: estudios genéticos, analíticos, hematológicos y urinarios. La corrección quirúrgica del megaloclítoris es necesaria no sólo para mejorar el aspecto de los genitales externos, sino también para que tanto la paciente como su familia se encuentren menos afectados psicológicamente. Existen varias técnicas quirúrgicas que intentan corregir esta malformación, como la amputación o clitorectomía total, la retroposición o enterramiento y la clitorectomía parcial selectiva. Todas ellas, junto con otras correcciones de los genitales externos afectados, han sido utilizadas hasta el día de hoy. Presentamos el caso de una paciente con Hiperplasia Suprarrenal Congénita por déficit del enzima 21-hidroxilasa. Describimos su clínica, la técnica quirúrgica aplicada en su caso y, sobre todo, dado la rareza de esta patología, comunicamos que, tras dos embarazos, los dos hijos nacidos, no presentaron la alteración congénita materna.

  19. Hiperplasia Suprarrenal Congénita: Reporte de un caso clínico.

    OpenAIRE

    Jaime Avaria E.; María José Vargas F.; Loreto Triviño F.; Andrea Gleisner E.

    2013-01-01

    INTRODUCCIÓN: La Hiperplasia suprarrenal congénita (HSC) es una enfermedad autosómica recesiva cuya principal causa es la deficiencia de 21-hidroxilasa, quien participa en la síntesis del cortisol y aldosterona. Se describen dos formas de HSC, una clásica y otra no clásica, siendo la primera el objetivo de análisis a lo largo del caso clínico. Sus manifestaciones clínicas varían en gravedad, dependiendo del nivel de deficiencia hormonal. Dentro de la clásica se describe la forma perdedora de ...

  20. Indicadores de calidad en hiperplasia benigna de próstata. Un estudio cualitativo

    OpenAIRE

    Navarro-Pérez, Jorge; Peiró, Salvador; Brotons-Muntó, Francisco; López-Alcina, Emilio; Real-Romaguera, Arcadio

    2014-01-01

    Objetivo: Valorar posibles indicadores de calidad de la atención a la hiperplasia benigna de próstata (HBP) y sus fortalezas y debilidades para su incorporación a los sistemas de información sanitaria. Diseño: Reunión de expertos, estructurada siguiendo procedimientos adaptados de las técnicas de grupo nominal y método de consenso Rand. Emplazamiento: Escuela Valenciana de Estudios de la Salud. Participantes y/o contextos: Participaron 40 panelistas (74% médicos, 70% del ámbito de la...

  1. Primary isolated gingival tuberculosis

    Directory of Open Access Journals (Sweden)

    Gabriel Rodrigues

    Full Text Available Tuberculosis of the oral cavity is a rare event and when present is usually secondary to pulmonary tuberculosis. We present a case of a 33-year-old male patient who presented with symptoms of gingivitis. Local examination revealed multiple ulcers and a few nodules over the gingiva. A nodule biopsy was consistent with the diagnosis of gingival tuberculosis. The patient had no evidence of tuberculosis any where else in the body. Medical treatment was curative. As this condition is very rare, it is often over looked as it is never thought as a common clinical diagnosis. A biopsy is mandatory to establish diagnosis. The relevant literature is reviewed.

  2. Gingivitis and periodontitis as antagonistic modulators of gingival perfusion.

    Science.gov (United States)

    Rodríguez-Martínez, Manuel; Patiño-Marín, Nuria; Loyola-Rodríguez, Juan Pablo; Brito-Orta, Ma Dolores

    2006-10-01

    We explore the possible association between the extent of gingivitis or periodontitis and an index of gingival microvascular perfusion response to compression of alveolar mucosa, called the gingival perfusion index (GIPI). A cross-sectional analytical study was done in a sample of 60 adults, including healthy and non-insulin-dependent diabetic subjects of either gender, with teeth in the anteromandibular sextant with or without gingivitis and with or without periodontitis at the lower-left lateral incisor (LLLI). A sample was selected by convenience non-probability sampling. Gingival perfusion was evaluated at labial LLLI attached gingiva. Two perfusion recordings were done 5 minutes apart, each one consisting of a 40-second control phase, a 22-second compression phase, and a 40-second postcompression phase. LLLI alveolar mucosa was compressed with a wood-mounted cotton swab until reaching about one-fifth of the control perfusion value. GIPI was used as response dependent variable. The gingival index and probing depth were used as measures of the extent of gingivitis and periodontitis, respectively. By analysis of covariance and multiple regression analysis, it was found that only the probing depth (negatively) and gingival index (positively) predicted GIPI (R(2) adjusted = 0.5194, P gingivitis and periodontitis operate as antagonistic modulators of gingival perfusion. The major practical implication of our findings is that an increase or decrease in this index (GIPI) at a given attached gingiva site could indicate, respectively, the clinical predominance of gingivitis or periodontitis in such a site.

  3. Necrotizing ulcerative gingivitis

    Directory of Open Access Journals (Sweden)

    Rayhana Malek

    2017-01-01

    Full Text Available Necrotizing ulcerative gingivitis (NUG is a typical form of periodontal diseases. It has an acute clinical presentation with the distinctive characteristics of rapid onset of interdental gingival necrosis, gingival pain, bleeding, and halitosis. Systemic symptoms such as lymphadenopathy and malaise could be also found. There are various predisposing factors such as stress, nutritional deficiencies, and immune system dysfunctions, especially, HIV infection that seems to play a major role in the pathogenesis of NUG. The treatment of NUG is organized in successive stages: first, the treatment of the acute phase that should be provided immediately to stop disease progression and to control patient's feeling of discomfort and pain; second, the treatment of the preexisting condition such as chronic gingivitis; then, the surgical correction of the disease sequelae like craters. Moreover, finally, maintenance phase that allows stable outcomes. This case report describes the diagnosis approach and the conservative management with a good outcome of NUG in a 21-year-old male patient with no systemic disease and probable mechanism of pathogenesis of two predisposing factors involved.

  4. Necrotizing Ulcerative Gingivitis.

    Science.gov (United States)

    Malek, Rayhana; Gharibi, Amina; Khlil, Nadia; Kissa, Jamila

    2017-01-01

    Necrotizing ulcerative gingivitis (NUG) is a typical form of periodontal diseases. It has an acute clinical presentation with the distinctive characteristics of rapid onset of interdental gingival necrosis, gingival pain, bleeding, and halitosis. Systemic symptoms such as lymphadenopathy and malaise could be also found. There are various predisposing factors such as stress, nutritional deficiencies, and immune system dysfunctions, especially, HIV infection that seems to play a major role in the pathogenesis of NUG. The treatment of NUG is organized in successive stages: first, the treatment of the acute phase that should be provided immediately to stop disease progression and to control patient's feeling of discomfort and pain; second, the treatment of the preexisting condition such as chronic gingivitis; then, the surgical correction of the disease sequelae like craters. Moreover, finally, maintenance phase that allows stable outcomes. This case report describes the diagnosis approach and the conservative management with a good outcome of NUG in a 21-year-old male patient with no systemic disease and probable mechanism of pathogenesis of two predisposing factors involved.

  5. Hiperplasia linfóide angiofolicular – Doença de Castleman – do mediastino: Apresentação de um caso clínico

    Directory of Open Access Journals (Sweden)

    Vítor Sousa

    2006-05-01

    Full Text Available Resumo: A hiperplasia linfóide angiofolicular foi inicialmente descrita por Castleman como uma hiperplasia do gânglio linfático, caracterizada por folículos anormais, com centros germinativos pequenos e marcada proliferação capilar.Os autores apresentam o caso de um homem de 37 anos com toracalgia e massa mediastínica com 4 cm de diâmetro, constituída por tecido vermelho-escuro e carnudo, com pequena área central branca. Foi diagnosticada a variante plasmocitária da hiperplasia linfóide angiofolicular em gânglio linfático mediastínico. Apresentava mais dois gânglios “diafragmáticos” envolvidos pela mesma doença.A hiperplasia linfóide angiofolicular, ou doença de Castleman, é uma doença linfoproliferativa rara que atinge frequentemente o mediastino ou os gânglios linfáticos do hilo pulmonar. Pode ter, no entanto, outras localizações, na forma multisistémica. Estão descritas duas variantes morfológicas: a vascular hialina e a plasmocitária. A IL-6 parece ter um papel importante na sua patogenia, quando se trata da variante plasmocitária. A doença de Castleman deve ser considerada no diagnóstico diferencial de massas mediastínicas, nomeadamente com linfomas. Abstract: Angiofolicular lymphoid hyperplasia was first described by Castleman as a lymph node hyperplasia characterized by abnormal follicles with small germinal centres and high capillary proliferation.The authors present a case of a 37 year old man with thoracalgy and a mediastinal mass of 4 cm diameter, fleshy and red with a white central area. The diagnosis of plasma cell type of angiofolicular lymphoid hyperplasia in an mediastinal lymph node was made. He also had involvement of two “diaphragmatic” lymph nodes.Angiofolicular lymphoid hyperplasia – Castleman's disease - is a rare lymphoproliferative disease that involves the mediastine or the pulmonary hilus

  6. Ácido tricloroacético, una opción terapéutica en la hiperplasia epitelial focal: Presentación de un caso Trichloroacetic acid, a therapeutic option in the focal epithelial hyperplasia: Presentation of a case

    OpenAIRE

    J. Harris Ricardo; M. Rebolledo Cobos; F. Camacho Chaljub; M. Carmona Lorduy; A. Díaz Caballero

    2010-01-01

    La Hiperplasia Epitelial Focal es una patología que se caracteriza por la presencia de múltiples pápulas en la mucosa de la cavidad oral, es de etiología viral, producida por subtipos del papiloma virus humano 13 y 32, normalmente se presenta en niños y adolescentes, rara vez afecta a adultos, las lesiones se encuentran con mayor frecuencia en las mucosas labial, yugal y Iingual. Entre las diferentes alternativas de tratamiento se encuentra la quirúrgica, criocirugía, vitamina A, nitrógeno lí...

  7. Gingival plasma cell granuloma

    Directory of Open Access Journals (Sweden)

    Amitkumar B Pandav

    2012-01-01

    Full Text Available Plasma cell granuloma, also known as inflammatory pseudotumor is a tumor-like lesion that manifests primarily in the lungs. But it may occur in various other anatomic locations like orbit, head and neck, liver and rarely in the oral cavity. We here report an exceedingly rare case of gingival plasma cell granuloma in a 58 year old woman who presented with upper gingival polypoidal growth. The histopathological examination revealed a mass composed of proliferation of benign spindle mesenchymal cells in a loose myxoid and fibrocollagenous stroma along with dense infiltrate of chronic inflammatory cells predominantly containing plasma cells. Immunohistochemistry for kappa and lambda light chains showed a polyclonal staining pattern confirming a diagnosis of plasma cell granuloma.

  8. Hiperplasia de Músculo Liso no Epidídimo: Revisão de Literatura/Smooth Muscle Hyperplasia of the Epididymis: A Literature Review

    Directory of Open Access Journals (Sweden)

    Ana Cecília Vieira Lisboa

    2014-12-01

    Full Text Available O epidídimo pode ser acometido por hiperplasia ou neoplasia, benigna ou maligna, sempre diferenciadas pelo estudo histopatológico. Ele tem como função coletar, amadurecer e armazenar espermatozóides constantemente produzidos pelos túbulos seminíferos. Patologias do epidídimo acometem homens na puberdade, o que pode resultar em alterações na maturação dos espermatozóides e até mesmo levar a infertilidade. A conduta dessa afecção é cirúrgica e pode ser desde ressecção da tumoração preservando-se estruturas hígidas como, por exemplo, os testículos, em casos benignos, até exploração peritoneal para esvaziamento linfonodal mais orquiectomia, em casos malignos. O objetivo foi realizar uma revisão de literatura sobre hiperplasia do epidídimo que auxilie no diagnóstico e tratamento precoces que diminuam a mortalidade, morbidade e sequelas dos pacientes. Como a patologia em questão tem baixa incidência, com predomínio de casos benignos e evolução sem complicações, conclui-se que há a necessidade de mais análises sobre o tema para melhor elucidar seu tratamento e, principalmente, as consequências. The epididymis may be affected by hyperplasia or neoplastic cells, always differentiated by histopathological study. It has the function of collecting, maturing and storing sperm that are constantly produced by the seminiferous tubules. Pathologies of epididymis affect male puberty, which may result in changes in the maturation of sperm and even lead to infertility. The conduct in this condition can be from a tumor resection preserving healthy structures such as, for example, the testicles, in benign cases, while in malignant cases chooses whether the peritoneal exploration for a lymph node dissection plus orchiectomy. The purpose was to conduct a literature review of hyperplasia of the epididymis that helps in the diagnosis and early treatment, which can lead to lower risk of mortality and morbidity allowing a decrease in

  9. Cultura Primária de Explant de Hiperplasia Prostática Benigna

    Directory of Open Access Journals (Sweden)

    Patrícia Borba Martiny

    2014-01-01

    Full Text Available A Hiperplasia Prostática Benigna (HPB é um crescimento patológico e não maligno da próstata causada principalmente pela proliferação exacerbada das células epiteliais e, principalmente, estromais. Essa neoplasia benigna acomete a maioria dos homens de idade avançada, sendo a condição crônica mais prevalente entre a população masculina. Como mostrado em estudos, o desenvolvimento prostático é intimamente dependente da interação entre as variantes celulares estromais e epiteliais presentes nesta glândula. Entretanto, a cocultura de ambos os tipos celulares é de difícil estabelecimento, uma vez que os dois tipos celulares têm diferentes características de adesão à placa de cultivo celular.

  10. Factores predisponentes para la inflamacion gingival asociada con coronas de acero en dientes temporales en la poblacion pediatrica. Revision sistematica de la literatura

    National Research Council Canada - National Science Library

    Madrigal Lopez, Daniela; Viteri Buendia, Esther Maria; Romero Sanchez, Mario Rafael; Colmenares Millan, Maria Marcela; Suarez, Angela

    2014-01-01

    Introduccion: el objetivo de esta revision sistematica fue determinar los factores predisponentes para la inflamacion gingival producidos por las coronas de acero, en comparacion con dientes temporales...

  11. Injerto de tejido conectivo en recesión gingival de incisivo

    OpenAIRE

    Luis Fang Mercado; Carmen Sierra Barrios; Alejandra Herrera Herrera; Carlos Leal Acosta; Antonio Diaz Caballero

    2013-01-01

    ResumenLa recesión gingival es definida como la ubicación del margen gingival apical a la unión amelocementaria de uno o más dientes. Esta deformidad apical ocasiona generalmente sensibilidad radicular, pobre apariencia estética y lesiones cervicales cariosas por lo que los pacientes pueden preguntar de manera frecuente a los clínicos por procedimientos de recubrimiento radicular. Existen dos grandes grupos de causas de recesión gingival, las que se originan de enfermedad periodontal y de ori...

  12. Exodoncia atraumática e implante post exodoncia sin colgajo combinado con injerto gingival libre

    OpenAIRE

    García Linares, Sixto; Yon Guerrero, Helen

    2010-01-01

    Presentamos un caso donde se describe la técnica de exodoncia atraumática, colocación de un implante post exodoncia y cierre por primera intención mediante un injerto gingival libre. El uso de implantes post exodoncia necesita varias condiciones para poder realizarse, entre ellas: paredes óseas conservadas, hueso alveolar más allá del ápice mayor a 4 mm. , margen gingival conservado, ausencia de fístula, etc. El injerto gingival libre permite una cicatrización por primera intención n...

  13. Gingival squamous cell carcinoma

    Directory of Open Access Journals (Sweden)

    Amit Walvekar

    2017-01-01

    Full Text Available Oral squamous cell carcinoma (OSCC is the most common epithelial malignancy affecting the oral cavity. The most common sites for the development are lateral surface of tongue and floor of mouth; the least common sites are soft palate, gingiva, and buccal mucosa. Gingival squamous cell carcinoma can mimic a multitude of oral lesions and enlargements, especially those of inflammatory origin. In addition, predisposing and presenting factors are different from those of other OSCCs. Careful examination as well as routine biopsy are crucial for accurate diagnosis.

  14. Clinical applicability of natural product(s-containing mouthwashes as adjunctive treatment of biofilm-induced gingivitis: a systematic review Aplicabilidade clínica de colutórios à base de produtos naturais como tratamento adjuvante da gengivite induzida por biofilme: uma revisão sistemática

    Directory of Open Access Journals (Sweden)

    I.A. Freires

    2012-01-01

    Full Text Available Natural products have emerged as an effective and low-cost alternative for treating various diseases of the oral cavity. This study aimed to evaluate, through a systematic literature review, if there is scientific evidence ensuring the safe and effective use of natural product(s-containing mouthwashes as adjunctive treatment of biofilm-induced gingivitis. Searches were conducted in the databases Medline, SciELO, LILACS and Cochrane Library, by using combinations of the key words gingivitis/natural products/phytotherapy/mouthwash, in English, Portuguese and Spanish. Studies published until September 2010 were considered. Four examiners analyzed independently: study design and phase, methodological quality (Jadad scale - JE, experimental product and its concentration, dosing interval and time of usage, as well as employed statistical analysis and clinical outcome of interest. From the 503 articles found, 08 were included in the final review as phase II, controlled, randomized and blind clinical trials, scoring 4 (25% and 5 (75% in JE. The main natural products assessed were: Azadirachta indica, Garcinia mangostana, Lippia sidoides, Salvadora persica and Sesamum indicum whose concentration, dosing interval, time of usage and adverse effects varied according to each study. The Plaque and Gingival Index were most employed, as well as α = 5% and paired t, Student's t, Wilcoxon and Mann-Whitney tests. A total of 62.5% and 50% of the products significantly reduced supragingival biofilm and gingivitis, respectively. Mouthwashes containing the essential oil from the leaves of L. sidoides (1% and the extract from the leaves of A. indica (25% can be indicated as adjunctive treatment of biofilm-induced gingivitis.Os produtos naturais têm surgido como alternativa eficaz e de baixo custo para o tratamento de várias doenças da cavidade oral. Objetivou-se avaliar, a partir de revisão sistemática da literatura, se há evidências científicas garantindo a

  15. Criterios actuales para evaluar la conducta a seguir con los pacientes que padecen de hiperplasia prostática benigna

    Directory of Open Access Journals (Sweden)

    Lourdes Santana Sarrhy

    2004-03-01

    Full Text Available El progreso de la biología y de la medicina en los últimos 20 años ha permitido avanzar en el conocimiento de la fisiopatología, morfología, sintomatología e incluso de nuevas alternativas terapéuticas en los pacientes con hiperplasia prostática benigna (HPB. Se llevó a cabo la presente investigación con el objetivo de evaluar los pacientes que asisten a nuestra consulta y que presentaban HPB a la luz de los nuevos criterios clínico-terapéuticos, e identificar la correlación existente entre estos criterios en dichos pacientes. Se realizó un estudio descriptivo de 56 pacientes con edades comprendidas entre los 50 y los 80 años de edad. A todos los casos se les llenó una encuesta donde se recogieron los síntomas urinarios, el examen físico, el resultado de la uroflujometría y la medición del residuo vesical. Los datos recogidos fueron analizados por métodos paramétricos y los resultados fueron llevados a tablas para una mejor comprensión de éstos. El 66,6 % de los pacientes que tenían un tacto rectal normal presentaban un flujo máximo obstructivo importante y el 50 % de los casos con próstata al tacto grado III tenían flujo no obstructivo. Del total de pacientes con flujo máximo por debajo de 10 mL/s, el 89,2 % tenía un residuo importante. El examen físico es útil para verificar la benignidad del proceso, pero el crecimiento de la glándula a través de la palpación digital no es proporcional al grado de obstrucción; que los síntomas obstructivos e irritativos aparecen con mayor frecuencia en los pacientes con un flujo urinario máximo menor de 10mL/seg. y que la medición del residuo vesical por ultrasonido abdominal nos es muy necesario para completar el estudio de estos pacientesThe progress of biology and medicine in the last years has allowed to advance in the knowldege of physiopathology, morphology, symptomatology and even of new therapeutic alternatives in patients with bening prostatic hyperplasia (BPH

  16. Effect of Gingivitis on Azithromycin Concentrations in Gingival Crevicular Fluid

    Science.gov (United States)

    Jain, Nidhi; Lai, Pin-Chuang; Walters, John D.

    2012-01-01

    Aim Macrolide antibiotics yield high concentrations in inflamed tissue, suggesting that their levels in gingival crevicular fluid (GCF) could be increased at gingivitis sites. However, the increased volume of GCF associated with gingivitis could potentially dilute macrolides. To determine whether these assumptions are correct, the bioavailability of systemically-administered azithromycin was compared in GCF from healthy and gingivitis sites. Materials and methods Experimental gingivitis was induced in one maxillary posterior sextant in nine healthy subjects. Contralateral healthy sextants served as controls. Subjects ingested 500 mg of azithromycin followed by a 250 mg dose 24 hours later. Four hours after the second dose, plaque was removed from experimental sites. GCF was collected from 8 surfaces in both the experimental and control sextants and pooled separately. GCF samples were subsequently collected on the 2nd, 3rd, 8th and 15th days and azithromycin content was determined by agar diffusion bioassay. Results On days 2 and 3, the pooled GCF volume at experimental sites was significantly higher than at control sites (P gingivitis sites and healthy sites, suggesting that the processes that regulate GCF azithromycin concentration can compensate for local inflammatory changes. PMID:22220766

  17. Synchronic rhynopharyngeal and gingival carcinoma

    OpenAIRE

    Boia, S; Onisei, D; Onisei, D; Boia, ER; Baderca, F; Balica, NC

    2016-01-01

    We present a case of a 38-year-old male who presented recurrent otitis media, maxillary gingival ulceration and no lateral cervical lymph nodes. Admission signs and symptoms: right: mild conductive hearing loss, trigeminal V2 nerve anaesthesia, ear tinnitus, hypoglossal nerve paralysis, minor maxillary gingival ulceration, Claude Bernard Horner's syndrome. A non-homogenous mass of 4.5/5.3/5.6 cm from the level of the right rhinopharyngeal wall, extending in the right parapharyngeal space, inv...

  18. Gingival prosthesis: A treatment modality for recession

    Directory of Open Access Journals (Sweden)

    Pallavi Samatha Yalamanchili

    2013-01-01

    Full Text Available Gingival recession caused due to periodontal disease disturbs patients because of sensitivity and esthetics. Gingival prosthesis may be fixed or removable and can be made from silicones, acrylics, composite resins or ceramics according to what is best suited for the case. The gingival veneer is esthetically appealing and easy to maintain. This case report describes the use of gingival veneer as a treatment modality for recession.

  19. A rare clinical presentation of sarcoidosis; gingivitis.

    Science.gov (United States)

    Güzel, Aygül; Köksal, Nurhan; Aydın, Davut; Aslan, Kerim; Gören, Fikret; Karagöz, Filiz

    2013-10-01

    Gingivitis due to sarcoidosis is a relatively rare condition. Gingivitis or isolated gingival involvement may be the first sign of systemic sarcoidosis. We report the case of a 37 year-old woman with isolated gingivitis due to sarcoidosis confirmed by biopsy. Following treatment with a systemic corticosteroid (prednisolone 40 mg/day), all clinical and radiologic findings were completely improved. In cases of chronic and intractable gingivitis, systemic sarcoidosis should be suspected. It should be confirmed with a biopsy, and the patient should be referred to a chest disease clinic to exclude other organ involvement. Copyright © 2013 Elsevier Inc. All rights reserved.

  20. Fibromatosis gingival hereditaria una inusual enfermedad genética: reporte de caso Hereditary gingival fibromatosis a rare genetic disease: case report

    Directory of Open Access Journals (Sweden)

    J Harris Ricardo

    2012-08-01

    Full Text Available Asociada a factores genéticos, que se caracterizada por aumento en el tamaño del tejido gingival, el cual genera dificultades emocionales, estéticas y funcionales. En el presente artículo se reporta un caso de una paciente femenina de 13 años con aumento generalizado en el volumen de la encía, que cubre casi todos los dientes, la historia familiar fue muy importante para el diagnóstico de fibromatosis gingival hereditaria, ya que la madre y un hermano presentaron la misma manifestación.Hereditary gingival fibromatosis is a rare disorder, associated with genetic factors, characterized by various degrees of attached gingival overgrowth, which generates emotional, aesthetic and functional disorders. This article reports the case of a 13-year-old female who presented a generalized severe gingival overgrowth, involving the maxillary and mandibular arches and covering almost the whole dentition. The family history was very important for the diagnosis of hereditary gingival fibromatosis, as the mother and a brother had the same disorder.

  1. The vaginal microflora in relation to gingivitis

    Science.gov (United States)

    2009-01-01

    Background Gingivitis has been linked to adverse pregnancy outcome (APO). Bacterial vaginosis (BV) has been associated with APO. We assessed if bacterial counts in BV is associated with gingivitis suggesting a systemic infectious susceptibilty. Methods Vaginal samples were collected from 180 women (mean age 29.4 years, SD ± 6.8, range: 18 to 46), and at least six months after delivery, and assessed by semi-quantitative DNA-DNA checkerboard hybridization assay (74 bacterial species). BV was defined by Gram stain (Nugent criteria). Gingivitis was defined as bleeding on probing at ≥ 20% of tooth sites. Results A Nugent score of 0–3 (normal vaginal microflora) was found in 83 women (46.1%), and a score of > 7 (BV) in 49 women (27.2%). Gingivitis was diagnosed in 114 women (63.3%). Women with a diagnosis of BV were more likely to have gingivitis (p = 0.01). Independent of gingival conditions, vaginal bacterial counts were higher (p gingivitis had higher counts of Prevotella bivia (p 1.0 × 104 cells) and a diagnosis of gingivitis was 3.9 for P. bivia (95% CI 1.5–5.7, p gingivitis in comparison to women with BV but not gingivitis. P. bivia and P. disiens may be of specific significance in a relationship between vaginal and gingival infections. PMID:19161595

  2. Relationship between diet and benign prostatic hyperplasia Relación entre la dieta y el desarrollo de Hiperplasia Prostática Benigna: ¿Qué nos dice la evidencia científica actual?

    Directory of Open Access Journals (Sweden)

    Jon Kepa Balparda Arias

    2010-02-01

    Full Text Available

    Benign prostatic hyperplasia is very common in the general population, both from the histological and the clinical points of view. The role of different factors in its development has been defined by means of epidemiological studies. One such factor is the composition of the diet, as the regular consumption of certain foods may either protect against benign prostatic hyperplasia or increase the risk of its development. Among foods which may play a protective role are lycopene, phytoestrogens and vegetables. On the other hand, the risk of developing the disease may be increased by a diet rich in fat and calories. In this article the main clinical trials concerning this relationship are reviewed, as a way of informing physicians on the dietetic patterns that may influence the frequency or the symptoms of this disease.

    La hiperplasia prostática benigna es muy común en la población general, tanto desde el punto de vista histológico como del clínico. El papel en ella de diversos factores se ha definido por medio de estudios epidemiológicos. Entre ellos está el consumo regular de algunos alimentos que podría actuar como un factor protector o de riesgo para el posterior desarrollo de la enfermedad. Entre los compuestos demostrados como benéficos para la salud prostática están los licopenos, los fitoestrógenos y las verduras. Por otro lado, entre los que podrían aumentar el riesgo de sufrir la hiperplasia prostática benigna se incluyen las dietas hipercal

  3. Multiple gingival pregnancy tumors with rapid growth

    Directory of Open Access Journals (Sweden)

    Wei-Lian Sun

    2014-09-01

    Full Text Available Pregnancy gingivitis is an acute form of gingivitis that affects pregnant women, with a prevalence of 30%, possibly ranging up to 100%. Sometimes, pregnancy gingivitis shows a tendency toward a localized hyperplasia called gingival pyogenic granuloma. Pregnancy tumor is a benign gingival hyperplasia with the gingiva as the most commonly involved site, but rarely it involves almost the entire gingiva. A 22-year-old woman was referred to our clinic with a chief complaint of gingival swelling that had lasted for 2 days. The lesions progressed rapidly and extensively, and almost all the gingiva was involved a week later. Generalized erythema, edema, hyperplasia, a hemorrhagic tendency, and several typical hemangiomatous masses were noted. Pregnancy was denied by the patient at the first and second visits, but was confirmed 2 weeks after the primary visit. The patient was given oral hygiene instructions. She recovered well, and the mass gradually regressed and had disappeared completely at the end of 12 weeks of pregnancy, without recurrence. The gingival lesions were finally diagnosed as multiple gingival pregnancy tumors. The patient delivered a healthy infant. An extensive and rapid growth of gingival pregnancy tumors during the early first month of pregnancy is a rare occurrence that is not familiar to dentists, gynecologists, and obstetricians. Those practitioners engaged in oral medicine and periodontology, primary care obstetrics, and gynecology should be aware of such gingival lesions to avoid misdiagnosis and overtreatment.

  4. Evaluation of efficacy of different gingival displacement materials on gingival sulcus width.

    Science.gov (United States)

    Prasanna, G S Renuka; Reddy, Kesava; Kumar, R K Naveen; Shivaprakash, S

    2013-03-01

    The purpose of the present in vivo study was to measure the efficacy of different gingival displacement materials in achieving gingival tissue displacement and to compare the efficacy of Expasyl displacement paste (Pierre Rolland, France) and gingival displacement cord for gingival displacement. Sixteen subjects were included in the study. Premolars were prepared to receive full veneer crown, gingival displacement was carried using gingival retraction cord and gingival displacement paste. Impression of the gingival sulcus was made. Sulcus width after displacement was measured under magnification. The mean displacement value of sulcus width was 0.21 ± 0.01 mm for the gingival retraction cord and 0.26 ± 0.02 mm for the gingival displacement paste. 'F' test was used for statistical analysis. Difference among the two test agents was statistically significant (p paste showed better response in achieving horizontal displacement of the gingival sulcus than gingival retraction cord. Gingival displacement helps in recording the unprepared tooth surface adjacent to the finish line in the impression being made, thereby helping a better marginal adaptation and emergence profile in the extracoronal restoration.

  5. Simplificando el tratamiento quirúrgico de la sonrisa gingival

    Directory of Open Access Journals (Sweden)

    H. Chacón Martínez

    Full Text Available La sonrisa es una de las expresiones más comunes del ser humano como muestra de satisfacción, alegría o felicidad. Algunas personas al sonreír muestran la encía por encima de la base de los dientes, lo que ocasiona un aspecto antiestético. Esta situación repercute negativamente en el individuo, ya que altera la espontaneidad de la expresión facial. En el origen de la sonrisa gingival intervienen factores dentales, esqueléticos y de tejidos blandos. Proponemos una variante quirúrgica innovadora para corregir la sonrisa gingival en pacientes con alteraciones de los tejidos blandos. Se intervinieron quirúrgicamente 15 mujeres de entre 17 y 38 años de edad. En 7 de ellas se practicó rinoplastia además de corrección de la sonrisa gingival. Las 8 restantes se sometieron exclusivamente a corrección de la sonrisa gingival. Las 15 pacientes intervenidas mejoraron su apariencia y autoestima. No hubo complicaciones o problemas relacionados con la herida quirúrgica. Los resultados han sido permanentes a medio y largo plazo. La sonrisa de las pacientes es normal, mejoró su expresión y se conservaron la sensibilidad y la función muscular. La técnica propuesta es sencilla y de fácil reproducción; el tiempo quirúrgico estimado es de una hora y la operación es de tipo ambulatoria. Suele ser bien tolerada por los pacientes y no altera sus actividades cotidianas.

  6. Unusual Gingival Enlargement: A Rare Case Report

    Directory of Open Access Journals (Sweden)

    Ashutosh Dixit

    2014-01-01

    Full Text Available This is an atypical case report of a 20-year-old male patient who suffered from unusual unilateral, gingival enlargement together with rapidly progressive alveolar bone loss. The enlarged gingiva completely covered his left posterior teeth in both arches. The patient was diagnosed with gingival fibromatosis and aggressive periodontitis based on the clinical, histological, and radiographic findings. The gingival enlargement was treated by conventional gingivectomy under local anaesthesia. The postoperative result was uneventful.

  7. Gingival cyst of adult: A rare case

    OpenAIRE

    Malali, Vijayalaxmi V.; Satisha, T. S.; Jha, A. K.; Rath, S. K.

    2012-01-01

    Gingival cyst of adult is an uncommon cyst of gingival soft tissue occurring in either the free or attached gingiva. This odontogenic epithelial cyst is most frequently seen near mandibular canine and premolar region, believed to represent the soft tissue counter part of the lateral periodontal cyst. This article presents a case of gingival cyst treated with exicisional biopsy followed by histopathological confirmation and an emphasis on the clinical aspects of this lesion.

  8. Treatment of gingival pigmentation : A case series

    OpenAIRE

    Prasad Deepak; Sunil S; Mishra R; Sheshadri

    2005-01-01

    A smile expresses a feeling of joy, success, sensuality, affection and courtesy, and reveals self confidence and kindness. The harmony of the smile is determined not only by the shape, the position and the color of the teeth but also by the gingival tissues. Gingival health and appearance are essential components of an attractive smile. Gingival pigmentation results from melanin granules, which are produced by melanoblasts. The degree of pigmentation depends on melanoblastic activity. Althoug...

  9. Tapered toothbrush filaments in relation to gingival abrasion, removal of plaque and treatment of gingivitis

    NARCIS (Netherlands)

    Versteeg, P.A.; Piscaer, M.; Rosema, N.A.M.; Timmerman, M.F.; van der Velden, U.; van der Weijden, G.A.

    2008-01-01

    Objectives: To compare a tapered filament toothbrush (TFTB) to a control toothbrush (ADA) in their potential to cause gingival abrasion and improve the gingival condition following a period of experimental gingivitis. Methods: Thirty-two subjects refrained from brushing mandibular teeth for 21 days.

  10. Non-drug induced gingival enlargement.

    Science.gov (United States)

    Moffitt, Michelle L; Cohen, Robert E

    2013-08-01

    Gingival enlargement refers to an increase in the size of the gingival tissue. The etiology varies, and often is multifactorial; however, local and systemic conditions, disease, and idiopathic factors may contribute to gingival enlargement. Tissue consistency can vary from soft and spongy to dense, typically appearing darker in shade compared to the drug-induced gingival enlargement. Treatment modalities usually involve surgical removal of excess tissue, non-surgical debridement, use of chemotherapeutic agents, and/or elimination or mitigation of contributing factors and conditions.

  11. Gingival Retraction Methods: A Systematic Review.

    Science.gov (United States)

    Tabassum, Sadia; Adnan, Samira; Khan, Farhan Raza

    2017-12-01

    The aim of this systematic review was to assess the gingival retraction methods in terms of the amount of gingival retraction achieved and changes observed in various clinical parameters: gingival index (GI), plaque index (PI), probing depth (PD), and attachment loss (AL). Data sources included three major databases, PubMed, CINAHL plus (Ebsco), and Cochrane, along with hand search. Search was made using the key terms in different permutations of gingival retraction* AND displacement method* OR technique* OR agents OR material* OR medicament*. The initial search results yielded 145 articles which were narrowed down to 10 articles using a strict eligibility criteria of including clinical trials or experimental studies on gingival retraction methods with the amount of tooth structure gained and assessment of clinical parameters as the outcomes conducted on human permanent teeth only. Gingival retraction was measured in 6/10 studies whereas the clinical parameters were assessed in 5/10 studies. The total number of teeth assessed in the 10 included studies was 400. The most common method used for gingival retraction was chemomechanical. The results were heterogeneous with regards to the outcome variables. No method seemed to be significantly superior to the other in terms of gingival retraction achieved. Clinical parameters were not significantly affected by the gingival retraction method. © 2016 by the American College of Prosthodontists.

  12. Reconstrucción genital integral en la Hiperplasia Suprarrenal Congénita: sensibilidad, estética y función (embarazo Integral genital reconstruction: sensitivity, aesthetic and function (pregnancy, in the Congenital Adrenal Hyperplasia

    Directory of Open Access Journals (Sweden)

    A.A. Núñez Serrano

    2010-03-01

    Full Text Available La Hiperplasia Suprarrenal Congénita o Síndrome Adrenogenital es un cuadro clínico poco frecuente. Las anomalías que presenta van asociadas a síndromes que a veces son muy complejos, destacando, entre otros, el seudohermafroditismo femenino y el hermafroditismo verdadero. Las mujeres que la padecen presentan como alteración más evidente un clítoris aumentado de tamaño (megaloclítoris y otras alteraciones en los genitales externos. Ante estas pacientes es necesario realizar un diagnostico correcto mediante exploración física y otras pruebas complementarias: estudios genéticos, analíticos, hematológicos y urinarios. La corrección quirúrgica del megaloclítoris es necesaria no sólo para mejorar el aspecto de los genitales externos, sino también para que tanto la paciente como su familia se encuentren menos afectados psicológicamente. Existen varias técnicas quirúrgicas que intentan corregir esta malformación, como la amputación o clitorectomía total, la retroposición o enterramiento y la clitorectomía parcial selectiva. Todas ellas, junto con otras correcciones de los genitales externos afectados, han sido utilizadas hasta el día de hoy. Presentamos el caso de una paciente con Hiperplasia Suprarrenal Congénita por déficit del enzima 21-hidroxilasa. Describimos su clínica, la técnica quirúrgica aplicada en su caso y, sobre todo, dado la rareza de esta patología, comunicamos que, tras dos embarazos, los dos hijos nacidos, no presentaron la alteración congénita materna.Congenital Adrenal Hyperplasia is a rare patology, whith clinical expressions like female pseudohermaphroditism or true hermaphroditism. Females affected mainly suffer clitoral hypertrophy and external genitalia abnormalityes. The complete diagnosis includes: careful examination of the genitals, complementary imaging proofs, hormonal and genetic testing. The surgical correction of the external genitals and megaloclitoris improves the physical and

  13. Correlação entre a nasofibrofaringoscopia e a cefalometria no diagnóstico de hiperplasia de tonsilas faríngeas

    OpenAIRE

    Ritzel,Rodrigo Agne; Berwig, Luana Cristina; Silva,Ana Maria Toniolo da; Corrêa, Eliane Castilhos Rodrigues; Serpa,Eliane Oliveira

    2012-01-01

    INTRODUÇÃO: A hiperplasia de tonsila faríngea é uma das principais causas da respiração oral. O diagnóstico preciso desta alteração é importante para o correto planejamento terapêutico. Em vista disso, estudos têm sido desenvolvidos a fim de fornecer subsídios quanto aos procedimentos que podem ser utilizados para o diagnóstico de obstrução faríngea. OBJETIVO: Verificar a correlação entre os exames de nasofibrofaringoscopia e cefalometria no diagnóstico de hiperplasia de tonsila faríngea. MÉT...

  14. Evidencia molecular y serológica de la asociación del PVH-13 con la hiperplasia epitelial focal en la comunidad indígena embera-chami de Jardín, Antioquia-Colombia

    Directory of Open Access Journals (Sweden)

    Juan Alberto Pérez

    2004-03-01

    Full Text Available

    Introducción: La hiperplasia epitelial focal (HEF o enfermedad de Heck es una entidad benigna de la mucosa oral que se presenta principalmente en jóvenes de grupos étnicos muy específicos. Aunque el epónimo de “Enfermedad de Heck” proviene del primer caso reportado en 1961 por el Dr. Heck en Nuevo Méjico, ya previamente en Colombia el Dr. Estrada en 1956 había reportado esta entidad en los indios Caramanta (1. Es así como en Colombia ha habido reportes de esta enfermedad en diferentes comunidades indígenas (2,3. La hiperplasia epitelial focal se caracteriza clínicamente por pápulas, nódulos o placas localizadas principalmente en la mucosa labial, los carrillos y la lengua.

    Desde 1989 se había sugerido su causa viral debido a la frecuente detección del PVH-13 y PVH-32 en las lesiones (4. En un estudio descriptivo previo realizado en el 2001 se encontró una prevalencia de la enfermedad del 13% en escolares de la comunidad indígena Embera-Chamí en Jardín, Antioquia (5. En ese mismo estudio logramos detectar la infección por PVH en un 80% de escolares con HEF.

    A pesar de que se ha sugerido una etiología viral de la HEF, hasta el momento no existía evidencia epidemiológica que demostrara la asociación del PVH con la hiperplasia epitelial focal. Por tal motivo, el objetivo de este trabajo fue el de confirmar molecular y serológicamente esta asociación. Diseño del estudio: Estudio de casos y controles. Materiales y métodos: La población estudiada de casos correspondió a los escolares que presentaban los criterios clínicos e histopatológicos de HEF. A estos casos se les tomó biopsia de una de las lesiones clínicamente evidentes.

    Prevalencia y grado de gingivitis asociada a placa dentobacteriana en niños

    OpenAIRE

    Miriam Lucía Rocha Navarro; Sanjuana Serrano Reyes; Martha Eugenia Fajardo Araujo; Víctor Hugo Giovani Servín Zavala

    2014-01-01

    Introducción: Las enfermedades periodontales (EPs) son comunes en niños y adolescentes, y algunas son rápidamente destructivas. El consenso internacional de Periodontología de 1999, vigente hasta hoy día, incluyó a la gingivitis como parte de las EPs. Este estudio se enfocó en la gingivitis inducida por placa dentobacteriana (PDB). Estudios previos reportan porcentajes similares de prevalencia en niños Nigerianos, Polacos y Tanzaneses de alrededor del 54.4%. Sin embargo Oh TJ y col. encontró ...

  15. Agrandamiento gingival inducido por nifedipinaReporte de un caso

    National Research Council Canada - National Science Library

    Antonio José Díaz Caballero; Luisa Arevalo Tovar; María Angélica Fonseca Ricaurte

    2009-01-01

    .... La nifedipina es la que principalmente se reporta que produce agrandamientos gingivales, al ser utilizada durante tratamientos largos para trastornos cardiovasculares, angina de pecho e hipertensión...

  16. Agrandamiento gingival inducido por nifedipina.Reporte de un caso

    National Research Council Canada - National Science Library

    Antonio José Díaz Caballero; Luisa Arevalo Tovar; María Angélica Fonseca Ricaurte

    2013-01-01

    .... La nifedipina es la que principalmente se reporta que produce agrandamientos gingivales, al ser utilizada durante tratamientos largos para trastornos cardiovasculares, angina de pecho e hipertensión...

  17. Agrandamiento gingival inducido por nifedipina.Reporte de un caso

    National Research Council Canada - National Science Library

    Antonio José Díaz Caballero; Luisa Arevalo Tovar; María Angélica Fonseca Ricaurte

    2013-01-01

    ... en las encías un crecimiento de este tejido. Se reporta que medicamentos tales como los bloqueadores de los canales de calcio, inmunosupresores, anticonvulsivantes pueden expresar esos efectos laterales...

  18. Agrandamiento gingival inducido por nifedipina.Reporte de un caso

    OpenAIRE

    Antonio José Díaz Caballero; Luisa Arevalo Tovar; María Angélica Fonseca Ricaurte

    2013-01-01

    ResumenEs bien conocido que el tratamiento con diversos tipos de medicamentos puede producir en las encías un crecimiento de este tejido. Se reporta que medicamentos tales como los bloqueadores de los canales de calcio, inmunosupresores, anticonvulsivantes pueden expresar esos efectos laterales. La nifedipina es la que principalmente se reporta que produce agrandamientos gingivales, al ser utilizada durante tratamientos largos para trastornos cardiovasculares, angina de pecho e hipertensión. ...

  19. Injerto de tejido conectivo en recesión gingival de incisivo

    Directory of Open Access Journals (Sweden)

    Luis Fang Mercado

    2013-10-01

    Full Text Available ResumenLa recesión gingival es definida como la ubicación del margen gingival apical a la unión amelocementaria de uno o más dientes. Esta deformidad apical ocasiona generalmente sensibilidad radicular, pobre apariencia estética y lesiones cervicales cariosas por lo que los pacientes pueden preguntar de manera frecuente a los clínicos por procedimientos de recubrimiento radicular. Existen dos grandes grupos de causas de recesión gingival, las que se originan de enfermedad periodontal y de origen traumático, además, se consideran ciertos factores y se les clasifica como factores predisponentes y precipitantes desencadenantes. Patológicamente las recesiones gingivales están ocasionadas por la destrucción de tejido conectivo de la encía, lo cual ocasiona una disminución del flujo sanguíneo a nivel gingival. Se desarrollan varias técnicas con el mismo fin, dentro de estas están el colgajo pediculado, injerto gingival libre, injerto de tejido conectivo y la regeneración tisular guiada. Las condiciones de éxito en el tratamiento de las recesiones gingivales, descansan en el conocimiento de su etiología y de las posibilidades de cicatrización de acuerdo a las diferentes técnicas quirúrgicas consideradas para corregirlas. Los objetivos a considerar en el tratamiento de las recesiones son: mejorar la estética, recubrir las zonas radiculares expuestas y lograr estabilidad clínica. Se presenta un caso clínico donde se utilizó el enfoque del injerto de conectivo subpediculado en un diente único para crear encía adherida y a la vez intentar cubrir una recesión en diente inferior anterior. (DUAZARY 2011 No. 2, 206 - 212.AbstractGingival recession is defined as the location of gingival margin apical to the CEJ one or more teeth. This deformity causes apical usually root sensitivity, poor appearance aesthetics and carious cervical lesions so that Patients may wonder procedures root coverage. There are two main groups causes of

  1. Gingivitis

    Science.gov (United States)

    ... Plaque forms on your teeth. Plaque is an invisible, sticky film composed mainly of bacteria that forms ... a not-for-profit organization and proceeds from Web advertising help support our mission. Mayo Clinic does ...

  2. Bacterial community development in experimental gingivitis.

    Directory of Open Access Journals (Sweden)

    James O Kistler

    Full Text Available Current knowledge of the microbial composition of dental plaque in early gingivitis is based largely on microscopy and cultural methods, which do not provide a comprehensive description of oral microbial communities. This study used 454-pyrosequencing of the V1-V3 region of 16S rRNA genes (approximately 500 bp, and bacterial culture, to characterize the composition of plaque during the transition from periodontal health to gingivitis. A total of 20 healthy volunteers abstained from oral hygiene for two weeks, allowing plaque to accumulate and gingivitis to develop. Plaque samples were analyzed at baseline, and after one and two weeks. In addition, plaque samples from 20 chronic periodontitis patients were analyzed for cross-sectional comparison to the experimental gingivitis cohort. All of the healthy volunteers developed gingivitis after two weeks. Pyrosequencing yielded a final total of 344,267 sequences after filtering, with a mean length of 354 bases, that were clustered into an average of 299 species-level Operational Taxonomic Units (OTUs per sample. Principal coordinates analysis (PCoA plots revealed significant shifts in the bacterial community structure of plaque as gingivitis was induced, and community diversity increased significantly after two weeks. Changes in the relative abundance of OTUs during the transition from health to gingivitis were correlated to bleeding on probing (BoP scores and resulted in the identification of new health- and gingivitis-associated taxa. Comparison of the healthy volunteers to the periodontitis patients also confirmed the association of a number of putative periodontal pathogens with chronic periodontitis. Taxa associated with gingivitis included Fusobacterium nucleatum subsp. polymorphum, Lachnospiraceae [G-2] sp. HOT100, Lautropia sp. HOTA94, and Prevotella oulorum, whilst Rothia dentocariosa was associated with periodontal health. Further study of these taxa is warranted and may lead to new

  3. Bacterial community development in experimental gingivitis.

    Science.gov (United States)

    Kistler, James O; Booth, Veronica; Bradshaw, David J; Wade, William G

    2013-01-01

    Current knowledge of the microbial composition of dental plaque in early gingivitis is based largely on microscopy and cultural methods, which do not provide a comprehensive description of oral microbial communities. This study used 454-pyrosequencing of the V1-V3 region of 16S rRNA genes (approximately 500 bp), and bacterial culture, to characterize the composition of plaque during the transition from periodontal health to gingivitis. A total of 20 healthy volunteers abstained from oral hygiene for two weeks, allowing plaque to accumulate and gingivitis to develop. Plaque samples were analyzed at baseline, and after one and two weeks. In addition, plaque samples from 20 chronic periodontitis patients were analyzed for cross-sectional comparison to the experimental gingivitis cohort. All of the healthy volunteers developed gingivitis after two weeks. Pyrosequencing yielded a final total of 344,267 sequences after filtering, with a mean length of 354 bases, that were clustered into an average of 299 species-level Operational Taxonomic Units (OTUs) per sample. Principal coordinates analysis (PCoA) plots revealed significant shifts in the bacterial community structure of plaque as gingivitis was induced, and community diversity increased significantly after two weeks. Changes in the relative abundance of OTUs during the transition from health to gingivitis were correlated to bleeding on probing (BoP) scores and resulted in the identification of new health- and gingivitis-associated taxa. Comparison of the healthy volunteers to the periodontitis patients also confirmed the association of a number of putative periodontal pathogens with chronic periodontitis. Taxa associated with gingivitis included Fusobacterium nucleatum subsp. polymorphum, Lachnospiraceae [G-2] sp. HOT100, Lautropia sp. HOTA94, and Prevotella oulorum, whilst Rothia dentocariosa was associated with periodontal health. Further study of these taxa is warranted and may lead to new therapeutic approaches

  4. Salivary and crevicular fluid interleukins in gingivitis

    Science.gov (United States)

    Boronat-Catalá, Montserrat; Bagán Sebastián, José V.

    2014-01-01

    Introduction: Gingivitis is a frequent inflammatory process of the gum tissue that is mainly caused by the accumulation of plaque. The immune response against inflammatory processes is regulated in part by cytokines. Aims: Given that a continuous inflammation exists in gingivitis, it would be logical to assume that the interleukins will be altered locally in those patients. Therefore, the aim of this review was to check whether there is evidence that the interleukins can be used as diagnostic markers of inflammation levels in patients with gingivitis. Materials and Methods: A bibliographical search was undertaken using the key words interleukin and gingivitis in Pubmed, Cochrane, Scopus and Embase. Only those articles published over the last 10 years that were systematic reviews, case-controls or cohort studies in which interleukins in saliva and/or crevicular fluid was investigated in patients with gingivitis were selected. Results: Finally 15 articles were selected, all of them being case-control studies. The interleukins analyzed in the reviewed articles were: IL-1β, IL-8, IL-18, IL-11, IL-12, TNFα, IL-4, IL-17, IL-1α and IL-6. The most commonly studied interleukin is IL-1β and most authors agree that it is higher in the saliva and/or crevicular fluid of patients with gingivitis. Therefore, it could be used as a diagnostic marker of the degree of inflammation in gingivitis. Moreover, as far as the other interleukins studied are concerned, there is no clear consensus among the authors. Conclusion: There is sufficient evidence to suggest that IL-1β in saliva and/or crevicular fluid can be used as a marker of the degree of inflammation in gingivitis. Key words:Interleukins, gingivitis, saliva, crevicular fluid. PMID:24790719

  5. Melanin: A scavenger in gingival inflammation

    Directory of Open Access Journals (Sweden)

    S Nilima

    2011-01-01

    Full Text Available Background: One of the major direct or indirect targets of ultraviolet exposure of skin is the melanocyte or the melanin -forming cell. Epidermal melanocytes act as a trap for free radicals. Based on the protective role of melanocytes in medical literature, the role of melanin pigmentation in gingiva needs to be elucidated. Periodontal pathogens and their products demonstrate the ability to induce the generation of reactive oxygen species. Hence purpose of this study was to unravel the protective role of melanin (if any against the gingival inflammation. Materials and Methods: A total of 80 subjects; 20 in each group were selected. The selection of subjects regarding gingival pigmentation was based on Dummett′s scoring criteria 0, 3. A complete medical, dental history and an informed consent were obtained from the patients. After evaluation of clinical parameters the GCF was collected using microcapillary pipettes at the selected sites. IL-1β levels were quantitated using ELISA. Results: In non-pigmented healthy and gingivitis groups, there was a positive correlation between plaque index, gingival index and bleeding index versus IL-1β level: indicating an increase in the biochemical mediator of inflammation corresponding to an increase in the clinical parameters of inflammation. Also a positive correlation was found between the gingival index and bleeding index versus the IL-1β levels in the pigmented healthy group. The pigmented gingivitis groups showed a negative correlation between the plaque index, gingival index and bleeding index. Conclusions: The clinical markers of inflammation such as gingival index, bleeding index was of low numerical value in pigmented group than in the non-pigmented group, supposedly due to the protective action of melanin. The negative correlation of clinical markers of inflammation to the IL-1β levels in the pigmented gingivitis group could possibly be attributed to the protective role of melanins.

  6. Acute Necrotizing Ulcerative Gingivitis (ANUG

    Directory of Open Access Journals (Sweden)

    Nicholas E. Kman

    2017-04-01

    Full Text Available History of Present Illness: A 34-year-old HIV positive female presented to the emergency department with a three-week history of swollen, painful gums. She had difficulty eating and chewing, along with aches and general malaise. The patient was an everyday smoker and was not taking any antiretroviral medication. Significant findings: Physical examination revealed inflamed gingiva, ulceration, and soft tissue necrosis (Image 1 along with mandibular lymphadenopathy (not shown. Given her symptoms, poor oral care, and her immunocompromised state, she was given a diagnosis of Acute Necrotizing Ulcerative Gingivitis (ANUG or Vincent’s Angina. Discussion: Acute Necrotizing Ulcerative Gingivitis (ANUG, Vincent’s Angina, or Trench Mouth is the only periodontal disease in which bacteria invade non-necrotic tissue. The etiology is usually secondary to fusobacteria and spirochete overgrowth of bacteria which is normally present in the oral cavity. HIV infection, previous necrotizing gingivitis, poor oral hygiene, malnutrition, smoking, and stress are predisposing factors. Antibiotics and improved nutrition have significantly decreased the incidence of ANUG. The prevalence of ANUG among HIV infected patients varies from 4.3% to 16.0%. ANUG is 20.8 times more likely to be seen in AIDS patients with CD4 counts less than 200 cells/mm3. In developing countries, like those in Sub-Saharan Africa, incidence of ANUG is increasing among children with a prevalence as high as 23% in children under 10 years of age.1 Treatment for ANUG is multifactorial. Patients need good debridement under anesthesia so dental referral is imperative. Pain control with Ibuprofen or low dose opioids is indicated. Oral hygiene instructions include Chlorhexidine 0.12% twice daily, proper nutrition, appropriate fluid intake, and smoking cessation. For signs of systemic involvement, the recommended antibiotics are Amoxicillin and Metronidazole.2 If left untreated, ANUG may lead to rapid

  7. Pregnancy gingivitis and causal inference.

    Science.gov (United States)

    Niederman, Richard

    2013-12-01

    The PubMed and Embase databases were searched together with hand searching of the Journal of Periodontology, Journal of Periodontal Research and Journal of Clinical Periodontology. The reference lists of identified articles were also searched. Prospective cohort or cross-sectional studies assessing the effect of pregnancy on gingival inflammation evaluated by the gingival index and/or bleeding on probing were included. Study quality was assessed using the Newcastle-Ottawa scale (NOS). Study assessment and data extraction were carried out independently by two reviewers, with disputes resolved by a third reviewer. Mean values of primary and secondary outcomes were directly pooled and analysed with weighted mean differences (WMDs) and 95% confidence intervals (CIs), considering independently each study design (cohort and cross-sectional). Study specific estimates were pooled with both the fixed- and random-effect models. Forty-four articles representing 33 studies (14 cohort and 19 cross-sectional) were included. Meta-analyses revealed a significantly lower GI in pregnant women in the first term compared with those in their second or third term of pregnancy; a lower mean GI score in post-partum women compared with women in their second [WMD = 0.143; 95% CI (0.031; 0.255); p = 0.012] or third term [WMD = 0.256; 95% CI (0.151; 0.360); p < 0.001] of pregnancy, when considering cohort studies; non-pregnant women had lower mean GI values than women in their second or third term of pregnancy. Small changes in plaque levels were reported. The results of this systematic review confirm that gingival inflammation is significantly increased throughout pregnancy and when comparing pregnant versus post-partum or non-pregnant women, without a concomitant increase in plaque levels. However, this information should be considered with caution, due to the small number of studies included in the meta-analyses, the low quality of the included studies, differences in study design, absence

  8. Oral gingival metastasis: A diagnostic dilemma

    Directory of Open Access Journals (Sweden)

    Nalini Aswath

    2017-01-01

    Full Text Available Oral cavity is a rare target for metastasis with an incidence of 1% among all oral cancers. In 24% of such cases, oral metastasis is the first indication of an undiagnosed primary. Metastatic oral malignancies have been reported in the mandible, tongue, and gingiva. Although gingival metastasis has been reported from lung, prostate, rectal carcinoma in men and carcinoma of breast, adrenal glands, and genitalia in females, gingival metastasis from carcinoma of the penis has not been reported. Herein, a case of metastatic gingival carcinoma that developed after extraction of teeth from primary carcinoma of the penis is presented. An extensive literature search revealed no such similar case reports.

  9. Monografía Histórica de la Hiperplasia Prostática Benigna

    Directory of Open Access Journals (Sweden)

    Jorge Cavelier

    1996-12-01

    Full Text Available

    Capitulo I
    La Próstata Desconocida

    Los médicos de la antigüedad reconocieron el fenómeno de la retención urinaria, pero en general atribuyeron esta condición a la presencia de cálculos vesicales. Su apreciación de la anatomía humana fue muy limitada y el significado potencial de la próstata en la retención urinaria no se realizó por muchos siglos. Ciertamente, la próstata fue identificada solamente durante la edad media y el renacimiento. En ese entonces no obstante las teorías fueron dominadas por el concepto de carnosidades y carúnculas y muy poco avance ocurrió en el conocimiento de las causas de la retención urinaria en el hombre.

    Medicina Greco-Romana
    En el transcurso de: mundo antiguo, la medicina y la religión estaban estrechamente relacionadas. Algunas prescripciones que permanecen válidas hoy en día tales como la importancia de una dieta balanceada y un ejercicio regular, fueron mezcladas con mistisismo.(2

    En la Grecia pre-hipocrática, la medicina estaba asociada con el culto de Asklepios, el dios griego de la salud. (1 (2 Los pacientes recibían tratamiento en los templos llamados Asklepieia donde ellos eran sanados por Asklepios o por sacerdotes médicos que actuaban bajo la guía de la deidad. Cuando la Asklepieia gradualmente cayó en desuso, el papel del sacerdote médico fue asumido por prácticamente de la ley cuyo trabajo preparó el camino al sistema hipocrático de la medicina clínica...

  10. Report a possible correlation between necrotizing ulcerative gingivitis and mononucleosis Reporte de una posible correlación entre la gingivitis ulceronecrotizante y la mononucleosis

    Directory of Open Access Journals (Sweden)

    Rosa Francinne Miranda

    2011-12-01

    Full Text Available Necrotizing ulcerative gingivitis is a relatively uncommon periodontal disease, characterized by ulceration, necrosis, pain and gingival bleeding. Factors often related to its occurrence include stress and systemic viral infections, such as those caused by cytomegalovirus and Epstein-Barr virus type 1, the latter being also considered the causative agent of infectious mononucleosis. This article aims to describe a clinical case of a female patient who presented with necrotizing ulcerative gingivitis associated with a clinical picture of infectious mononucleosis, as well as to review the literature concerning a possible correlation between these pathologies. This patient presented to our health care facility with necrotizing ulcerative gingivitis accompanied by lymphadenopathy, fever and prostration, after laboratory tests, Epstein-Barr virus type 1 infection was confirmed, as well as the co-occurrence of pathologies: necrotizing ulcerative gingivitis and infectious mononucleosis. Symptom remission in both disorders also occurred concomitantly, after instruction in plaque control measures and palliative medication for control of systemic symptoms. Therefore, although there is no scientific validation of an association between these two pathologies, it is imperative that all diagnostic alternatives be considered and investigated, in order to establish the therapeutic approach most appropriate to the patient.La gingivitis ulcerativa necrótica es una enfermedad periodontal no común caracterizada por ulceración, necrosis, dolor y sangrado gingival. Los factores a menudo relacionados con su ocurrencia incluyen el estrés y las infecciones virales sistémicas como aquellas causadas por Cytomegalovirus y el virus Epstein-Barr tipo 1, donde este último es el agente causal de la mononuclerosis infecciosa. El objetivo de este trabajo fue describir el caso clínico de una mujer con gingivitis ulcerativa necrótica asociada a un cuadro clínico de

  11. Treatment of gingival recession in two surgical stages: Free gingival graft and connective tissue grafting.

    Science.gov (United States)

    Henriques, Paulo Sergio Gomes; Nunes, Marcelo Pereira; Pelegrine, Andre Antonio

    2011-01-01

    This report describes a clinical case of severe Miller Class II gingival recession treated by two stages of surgery that combined a free gingival graft and connective tissue grafting. First, a free gingival graft (FGG) was performed to obtain an adequate keratinized tissue level. Three months later, a connective tissue graft (CTG) was performed to obtain root coverage. The results indicated that the FGG allows for a gain in the keratinized tissue level and the CTG allows for root coverage with decreased recession level after 16 months. Therefore, for this type of specific gingival recession, the combination of FGG and CTG can be used.

  12. [Metabolism of ornithine in human gingival tissue].

    Science.gov (United States)

    Pinna, G G; Chessa, G; Luglié, P F; Trova, R; Sisini, A

    1989-11-01

    The behavior of two enzymes of the ornithine pathway, leading to the formation of proline and, eventually, of collagen, arginase and ornithine oxo-acid aminotransferase has been investigated in normal and inflamed gingival tissue. Both enzymatic activities show a statistically significant decrease in pathological samples as compared to normal ones. The data on arginase activity may be in agreement with the already documented low level of urea in pathological gingival fluid, while a decrease of the ornithine aminotransferase activity could be linked to the phenomenon of gingival retraction, i.e. the lack of complete regeneration of gingival tissue usually observed in chronically inflamed subjects, that would be reasonably parallel to a decreased proline/collagen synthesis.

  13. Phenytoin- and amlodipine-induced gingival overgrowth

    Directory of Open Access Journals (Sweden)

    Ching-Wen Chang

    2012-03-01

    Full Text Available Drug-induced gingival overgrowth is an adverse event associated with three types of drugs, i.e., anticonvulsants, immunosuppressants, and calcium-channel blockers. It was shown that the combined use of an immunosuppressant (cyclosporine and a calcium-channel blocker increases the prevalence and severity of gingival overgrowth. However, few reports discussed the effects of the combination of an anticonvulsant (phenytoin and a calcium-channel blocker (amlodipine. In this case report, we present an epilepsy patient who was using both phenytoin and amlodipine, which caused extensive gingival overgrowth. After periodontal treatment and a gingivectomy, the gingival overgrowth was significantly reduced. A postoperative drug-substitution regimen and intensive professional care ensured a stable result 1 year after surgery.

  14. Multipotent progenitor cells in gingival connective tissue.

    Science.gov (United States)

    Fournier, Benjamin P J; Ferre, François C; Couty, Ludovic; Lataillade, Jean-Jacques; Gourven, Murielle; Naveau, Adrien; Coulomb, Bernard; Lafont, Antoine; Gogly, Bruno

    2010-09-01

    The gum has an exceptional capacity for healing. To examine the basis for this property and explore the potential of conferring it to organs with inferior healing capacity, we sought the presence of progenitor cells in gingival connective tissue. Colony-forming units of fibroblast-enriched cells from gingival fibroblast cultures were assessed for expression of membrane markers of mesenchymal stem cells; capacity to differentiate into osteoblasts, chondroblasts, and adipocytes; and engraftment efficiency after in vivo transfer. On the basis of their ability to differentiate into several lineages, proliferate from single cells, induce calcium deposits, and secrete collagen in vivo after transfer on hydroxyapatite carriers, we suggest that this population represents gingival multipotent progenitor cells. The discovery of progenitor cells in gingival connective tissue may help improve our understanding of how the wounded gum is capable of almost perfect healing and opens the prospect of cellular therapy for wound healing using readily available cells at limited risk to the patient.

  15. Bacterial community development in experimental gingivitis

    National Research Council Canada - National Science Library

    Kistler, James O; Booth, Veronica; Bradshaw, David J; Wade, William G

    2013-01-01

    Current knowledge of the microbial composition of dental plaque in early gingivitis is based largely on microscopy and cultural methods, which do not provide a comprehensive description of oral microbial communities...

  16. Chronic desquamative gingivitis as part of mucocutaneous ...

    African Journals Online (AJOL)

    In this paper, the clinical features of dermatoses or mucocutaneous disorders where desquamative gingivitis is presenting manifestations have been reviewed (lichen planus, mucous membranes pemphigoid and pemphigus vulgaris). Other less common mucocutaneous disorders affecting the oral mucosa (lupus ...

  17. Laser Gingival Retraction: A Quantitative Assessment

    Science.gov (United States)

    Krishna Ch, Vamsi; Gupta, Nidhi; Reddy, K. Mahendranadh; Sekhar, N. Chandra; Aditya, Venkata; Reddy, G.V.K. Mohan

    2013-01-01

    Background: Proper gingival retraction improves the prognosis of crowns and bridges with sub gingival finishlines.Use of lasers assists the operator to achieve proper retraction with good clinical results. Aims: The present study was intended to assess the amount of lateral gingival retraction achieved quantitatively by using diode lasers. Settings and Design: Study was carried on 20 patients attended to a dental institution that underwent root canal treatment and indicated for fabrication of crowns. Material and Methods: Gingival retraction was carried out on 20 teeth and elastomeric impressions were obtained. Models retrieved from the impressions were sectioned and the lateral distance between finish line and the marginal gingival was measured using tool makers microscope. Retraction was measured in mid buccal, mesio buccal and disto buccal regions. Statistical Analysis: The values obtained were used to calculate the mean lateral retraction in microns. Results: Mean retraction values of 399.5 μm, 445.5 μm and 422.5μm were obtained in mid buccal, mesio buccal and disto buccal regions respectively. Conclusions: Gingival Retraction achieved was closer to the thickness of sulcular epithelium and greater than the minimum required retraction of 200um. PMID:24086914

  18. Salivary cytokine levels in early gingival inflammation

    DEFF Research Database (Denmark)

    Belstrøm, Daniel; Damgaard, Christian; Könönen, Eija

    2017-01-01

    Salivary protein levels have been studied in periodontitis. However, there is lack of information on salivary cytokine levels in early gingival inflammation. The aim of this study was to determine salivary levels of vascular endothelial growth factor (VEGF), interleukin (IL)-8, monocyte chemoattr......Salivary protein levels have been studied in periodontitis. However, there is lack of information on salivary cytokine levels in early gingival inflammation. The aim of this study was to determine salivary levels of vascular endothelial growth factor (VEGF), interleukin (IL)-8, monocyte...... chemoattractant protein (MCP)-1, IL-1β, and IL-1 receptor antagonist (IL-1Ra) in gingival inflammation. Twenty-eight systemically and orally healthy nonsmokers abstained from oral hygiene protocols for 10 days. After that, self-performed cleaning was resumed for 14 days. Plaque and gingival indexes were measured...... levels decreased and remained low during development and resolution of experimental gingivitis. Initial inflammation in gingival tissues is associated with a decrease in inflammatory cytokines in saliva. Further studies are needed to evaluate if inflammatory cytokines bind to their functional receptors...

  19. Hiperplasia Suprarrenal Congénita: Revisão de 20 Casos da Consulta de Endocrinologia Pediátrica

    OpenAIRE

    Sousa, S. Gama de; A. Aguiar; Fontoura, M

    2014-01-01

    OBJECTIVO - Avaliar a apresentação clínica, crescimento e controlo metabólico de um grupo de doentes com Hiperplasia suprarrenal congénita (HSRC) diagnosticada antes dos 3 anos de idade.MÉTODOS - Foi efectuado um estudo longitudinal retrospectivo. Obtivemos uma amostra de 20 doentes (12 com a forma perdedora de sal, 8 com a forma virilizante simples) seguidos na consulta durante 9,1 anos (+/- 6,25 anos).RESULTADOS - Foi encontrada história familiar de HSRC em 40% dos casos. A idade média de d...

  20. Fotovaporización con láser verde para el tratamiento de la hiperplasia benigna de próstata

    OpenAIRE

    González-Chamorro Ladrón de Guevara, Fernando

    2011-01-01

    La hiperplasia benigna de próstata (HBP) es un proceso patológico benigno de proliferación celular que lleva al crecimiento del tamaño prostático y así al aumento de resistencia de salida al flujo miccional; lo que contribuye a los síntomas del tracto urinario (STUI) de los hombres de edad avanzada. Esto produce una afectación de la calidad de vida de los pacientes que la padecen hasta, en sus casos más avanzados, precisar una sonda vesical. El tratamiento es escalonado, disponiendo en el mom...

  1. Recesión gingival, maloclusión y tratamiento ortodoncico. Análisis de los hallazgos descritos en la literatura

    OpenAIRE

    Machuca, M. C.; Machuca-Portillo, Guillermo; Martínez, Francisco; Gallardo-Castillo, I; Bullon, Pedro

    1997-01-01

    Dado que se ha completado la malposición dentaria como sustrato anatómico predisponente, y el tratamiento de ortodoncia "per se" como factor precipitante de la recesión gingival, presentamos una revisión de la literatura comparando las diversas teorías propuestas por los distintos autores sobre la recesión gingival, maloclusión y tratamiento de ortodoncia. It has been reported that gingival recession may account like a consecuence of dental malposition and orthodontic treatment. In this wa...

  2. Influencia de factores perinatales en la pesquisa neonatal de hiperplasia adrenal congénita en Ciudad de La Habana y La Habana Influence of perinatal factors on the neonatal screening of congenital adrenal hyperplasia in Ciudad de La Habana

    Directory of Open Access Journals (Sweden)

    Tania Mayvel Espinosa Reyes

    2012-04-01

    Full Text Available Introducción: los costos económicos y psicosociales asociados con los resultados falsos positivos de la pesquisa neonatal de hiperplasia adrenal congénita son altos. Objetivos: identificar los factores perinatales que intervienen en la elevación y en el tiempo de normalización de los valores de 17 hidroxiprogesterona (17OHP, en pacientes no afectados por hiperplasia adrenal congénita. Métodos: se realizó un estudio descriptivo longitudinal retrospectivo en 1 114 pacientes procedentes de Ciudad de La Habana y La Habana, con resultados falsos positivos en la pesquisa, desde enero/2007 hasta junio/2010. Se identificaron las diferencias en la frecuencia de los factores perinatales reconocidos en este grupo con una muestra de población general, y otra integrada por enfermos de hiperplasia adrenal congénita. Resultados: de los pacientes falsos positivos, el 50,7 % pertenecía al sexo masculino y 49,3 % al femenino. El 54,7 % nació por cesárea, y el 82 % no presentó sufrimiento fetal agudo, aquellos con menor edad gestacional y peso al nacer más bajo presentaron niveles medios de 17OHP más elevados. El 68,1 % normalizó la 17OHP al cumplir un mes de vida, independientemente del tipo de parto y de la presencia de sufrimiento fetal agudo; pero la edad gestacional y el peso al nacer tuvieron correlación inversa con la persistencia de su elevación. Predominó el parto eutócico en los neonatos enfermos y normales, y la cesárea en los falsos positivos. La media de la edad gestacional y del peso al nacer fue significativamente menor en los casos en el primer grupo, comparada con la de los grupos restantes. Conclusiones: la prematuridad y el bajo peso al nacer tuvieron una influencia significativa sobre la elevación y la persistencia de los valores de 17OHP, no así el tipo de parto y el sufrimiento fetal agudo.Introduction: the psychosocial and economic costs associated with the false-positive results of the neonatal screening of

  3. Salivary cytokine levels in early gingival inflammation

    DEFF Research Database (Denmark)

    Belstrøm, Daniel; Damgaard, Christian; Könönen, Eija

    2017-01-01

    Salivary protein levels have been studied in periodontitis. However, there is lack of information on salivary cytokine levels in early gingival inflammation. The aim of this study was to determine salivary levels of vascular endothelial growth factor (VEGF), interleukin (IL)-8, monocyte chemoattr......Salivary protein levels have been studied in periodontitis. However, there is lack of information on salivary cytokine levels in early gingival inflammation. The aim of this study was to determine salivary levels of vascular endothelial growth factor (VEGF), interleukin (IL)-8, monocyte...... chemoattractant protein (MCP)-1, IL-1β, and IL-1 receptor antagonist (IL-1Ra) in gingival inflammation. Twenty-eight systemically and orally healthy nonsmokers abstained from oral hygiene protocols for 10 days. After that, self-performed cleaning was resumed for 14 days. Plaque and gingival indexes were measured......, and saliva samples were collected at days 1, 4, 7, 10, and 24. Salivary cytokines were detected with Luminex®-xMAP™. Salivary IL-1β, IL-1Ra, and VEGF levels decreased after 10 days' development of experimental gingivitis and reached baseline levels at the end of the 2-week resolution period. Salivary IL-8...

  4. An unusual case of generalized severe gingival enlargement during pregnancy.

    Science.gov (United States)

    McIntosh, Crystal L; Kolhatkar, Shilpa; Winkler, James R; Ojha, Junu; Bhola, Monish

    2010-01-01

    Increased hormone levels that are present during puberty and pregnancy are associated with localized or generalized gingival enlargement. This article reviews the gingival alterations that can occur during pregnancy and describes a case of generalized severe gingival enlargement associated with pregnancy and its management. A 36-year-old woman had severe bilateral gingival enlargement of short duration. The patient denied taking any medications. The laboratory report revealed no systemic abnormalities; however, the report disclosed that she was pregnant. Surgical therapy for the gingival enlargement included gingivectomy and gingivoplasty of all quadrants, which reduced the size of the enlarged gingiva. Postoperative visits demonstrated uneventful healing, with no recurrence seen at the one-year follow-up appointment. It appears that the English literature includes only one other case report that discusses generalized gingival enlargement during pregnancy. Pregnancy-related gingival enlargement should be included as a differential diagnosis in women who have non-drug-induced generalized gingival enlargement.

  5. Diagnostic considerations concerning a case of an unusual gingivitis

    NARCIS (Netherlands)

    van der Haring, I.S.; Witjes, M.J.H.

    2006-01-01

    A young woman presented a severe gingivitis that wouldn't respond to antibiotics prescribed by her general practitioner. Thorough clinical examination showed atypical gingival inflammation. In such unusual cases a careful anamnesis is essential in determining appropriate continued diagnostic

  6. FELINE MAMMARY HYPERPLASIA: THERAPEUTIC SUCCESS WITH THE USE OF THE AGLEPRISTONE HIPERPLASIA MAMÁRIA FELINA: SUCESSO TERAPÊUTICO COM O USO DO AGLEPRISTONE

    Directory of Open Access Journals (Sweden)

    Paulo Fernando Cisneiros da Costa Reis

    2008-12-01

    Full Text Available The feline mammary hyperplasia corresponds to a dependent injury of natural or synthetic progesterone. Although it is a benign condition, the clinical presentation, many times, it is an emergency. Thus the use of immediate protocols becomes necessary, as the use of aglepristone, which corresponds to a progesterone-antagonist drug. The aim of the present study corresponded to the description a case of feline mammary hyperplasia, with therapy the base of aglepristone. A feline, female, nine months of age, it presented description of increase of mammary volume, after the administration of a dose of contraceptive (medroxyprogesterone acetate. In virtue of anamnesis and the physical examination the diagnosis of mammary hyperplasia was established and was opted to the use of aglepristone, in the posology of 10mg/kg, to each 24h, during five days, it route subcutaneous. All the mammary glands presented symmetrical hyperplasia, with firm-elastic consistency. From the third day of the administration, it was observed that the glands were with more elastic consistency and lesser volume. After 23 days of the first dose, it had complete regression of the tissue mammary and the animal was neutered. Aglepristone if disclosed as an efficient therapy and insurance.

    KEY WORDS: Aglepristone, feline, hyperplasia, mammary gland. A hiperplasia mamária felina corresponde a uma lesão dependente de substâncias progestacionais naturais ou sintéticas. Embora seja uma condição benigna, a apresentação clínica, muitas vezes, é emergencial. Assim, torna-se necessário o uso de protocolos imediatos, como o uso do aglepristone, um fármaco antiprogestágeno. O presente trabalho descreveu um caso de hiperplasia mamária felina, com terapia à base de aglepristone. Um felino, fêmea, siamês, nove meses de idade, apresentou histórico de aumento de volume mamário após administração de uma dose do contraceptivo acetato de medroxiprogesterona. De acordo

  7. Etiology and occurrence of gingival recession - An epidemiological study

    Directory of Open Access Journals (Sweden)

    Sarpangala Mythri

    2015-01-01

    Full Text Available Objectives: Gingival recession is the term used to characterize the apical shift of the marginal gingiva from its normal position on the crown of the tooth. It is frequently observed in adult subjects. The occurrence and severity of the gingival recession present considerable differences between populations. To prevent gingival recession from occurring, it is essential to detect the underlying etiology. The aim of the present study was to determine the occurrence of gingival recession and to identify the most common factor associated with the cause of gingival recession. Methods: A total of 710 subjects aged between 15 years to 60 years were selected. Data were collected by an interview with the help of a proforma and then the dental examination was carried out. The presence of gingival recession was recorded using Miller's classification of gingival recession. The Silness and Loe Plaque Index, Loe and Silness gingival index, community periodontal index were recorded. The data thus obtained were subjected to statistical analysis using Chi-square test and Student's unpaired t-test. Results: Of 710 subjects examined, 291 (40.98% subjects exhibited gingival recession. The frequency of gingival recession was found to increase with age. High frequency of gingival recession was seen in males (60.5% compared to females (39.5%. Gingival recession was commonly seen in mandibular incisors (43.0%. Miller's class I gingival recession was more commonly seen. The most common cause for gingival recession was dental plaque accumulation (44.1% followed by faulty toothbrushing (42.7%. Conclusion: Approximately half of the subjects examined exhibited gingival recession. The etiology of gingival recession is multifactorial, and its appearance is always the result of more than one factor acting together.

  8. Response of chronic gingivitis to hygiene therapy and experimental gingivitis. Clinical, microbiological and metabonomic changes.

    Science.gov (United States)

    Klukowska, Malgorzata; Goyal, C Ram; Khambe, Deepa; Cannon, Michael; Miner, Melanie; Gurich, Nataliya; Circello, Ben; Huggins, Tom; Barker, Matthew L; Furnish, Carrie; Conde, Erinn; Hoke, Phyllis; Haught, Chris; Xie, Sancai; White, Donald J

    2015-10-01

    To compare the clinical, microbiological and metabonomic profiles of subjects with high and low levels of chronic gingival bleeding during a controlled oral hygiene regimen intervention including sequential phases of rigorous therapeutic oral hygiene followed by experimental gingivitis (EG). Two cohorts of qualified study subjects with differences in gingival bleeding on probing levels at their baseline clinical examination were entered into the study. These two cohorts were followed through three separate study phases including a 1-week baseline phase, a 2-week phase of rigorous oral hygiene including dental prophylaxis, and a 3-week EG phase of no oral hygiene to encourage relapse of gingivitis. The 58 subjects were assessed during each phase of the study for clinical presentation of gingivitis and concurrently had plaque sampled for real-time polymerase chain reaction (RTPCR) microbiological characterization and salivary lavage samples for 'systems biology' metabonomics assessment by 1H-NMR. Subjects presenting with different levels of gingival bleeding on probing when they entered the study responded differently to rigorous oral hygiene and EG. Specifically, the high bleeding cohort responded sluggishly to rigorous oral hygiene and exhibited markedly greater relapse to gingivitis during EG. RTPCR analysis showed changes in bacterial populations that were associated with study phases, particularly the increases in putative periodontal pathogens during EG. However, the microbiological profiles of high- and low-susceptibility gingival bleeding patients were largely similar. Metabonomic analysis likewise revealed significant changes in metabolite composition during study phases associated with differences in plaque toxicity, especially the short chain carboxylic acids propionate and n-butyrate, which tracked clinical changes in gingivitis severity. Systems analysis of metabonomic changes suggested differences between cohorts, although analysis to date has not

  9. [Orthodontic treatment of gingival recession: indications].

    Science.gov (United States)

    Delsol, Laurent; Bousquet, Philippe

    2011-09-01

    Gingival recession is a complex phenomenon. Root coverage results can be predictable regarding to the anatomy of the area. This includes the width of keratinized and attached gingiva, the buccolingual dimension of both soft tissue and alveolar bone, and the position and angulation of the teeth. If the tooth is out of the envelope of the alveolar process, with alveolar bone dehiscence and low thickness of the marginal soft tissue, the recession risk is important. Many techniques have been introduced to treat gingival recession. But lots of failures are linked to tooth position. An adequate orthodontic therapy, with controlled tooth movement, can improve periodontal tissues and thus improves the esthetical outcome. In some cases, orthodontic treatment is suggested to lead to an improved periodontal condition without pre-orthodontic gingival augmentation. © EDP Sciences, SFODF, 2011.

  10. Gingival Harmony in Anterior Aesthetic Restorations

    Directory of Open Access Journals (Sweden)

    Dalenda Hadyaoui

    2014-12-01

    Full Text Available This article describes a case of gingival asymmetry with compromising aesthetics. A 25-year-old dental student presented to the department of prosthetic dentistry. She was concerned about the greyish transparency of the crown metal margin through the marginal gingiva. The crown was placed to restore her lateral incisor. A comprehensive examination revealed that this unaesthetic aspect was caused by a non-harmonious gingival architecture in the lateral incisor marked by an unaesthetic gingival Zenith. The treatment plan included a surgical crown lengthening followed by prosthetic therapy consisting in a Zirconia based crown replacing the old prosthesis. Thanks to a well-planned multi-disciplinary approach, the result was esthetically acceptable and the patient was satisfied.

  11. Primary gingival tuberculosis: A rare clinical entity

    Directory of Open Access Journals (Sweden)

    Geeti Gupta

    2011-01-01

    Full Text Available Tuberculosis is a specific granulomatous infectious disease and a major cause of death in developing countries. Primary gingival tuberculosis is extremely rare and forgotten entity. Oral lesions usually appear as secondary to primary tuberculosis infection elsewhere. The lesion may take the form of nodules, ulcers, or elevated fissures. We report a case of primary tuberculosis of gingiva, manifesting as gingival enlargement with ulceration and discharge. Diagnosis was based on histopathologic examination, complete blood count, chest X-ray, and immunologic investigations with detection of antibodies against Mycobacterium tuberculosis. With the recent increase in the incidence of tuberculosis, this case report also emphasizes the need for clinicians to be aware of this possibility, consider tuberculosis in the differential diagnosis of gingival enlargement, and thus, play a role in the early detection of this disease.

  12. Tuberculous gingival enlargement: A rare clinical manifestation

    Directory of Open Access Journals (Sweden)

    Maria Subash Aaron Muthuraj

    2017-01-01

    Full Text Available Tuberculosis (TB is an inflammatory granulomatous disease that rarely presents as primary lesion in gingiva. Gingival involvement has been reported in only a very limited number of cases. A 13-year-old boy presented with gingival enlargement in the maxillary and mandibular anterior region associated with enlargement of lower lip with no systemic manifestations. He had a history of tuberculous lymphadenitis before 5 years which was inadequately treated. The patient's erythrocyte sedimentation rate was 70 mm/h. Histopathological report of the gingival lesion revealed noncaseating granulomas with nests of epithelioid cells and multinucleated Langhans giant cells. The patient was then referred to a physician for management, who initiated active antitubercular treatment following which the condition resolved. The aim of this article is to emphasize the importance of early diagnosis of primary TB of the gingiva which may be misdiagnosed when oral lesions are not associated with any apparent systemic infection.

  13. Tuberculous gingival enlargement: A rare clinical manifestation.

    Science.gov (United States)

    Aaron Muthuraj, Maria Subash; Maradi, Arun Parappa; Janakiram, Srihari; Chithresan, Koshy

    2017-01-01

    Tuberculosis (TB) is an inflammatory granulomatous disease that rarely presents as primary lesion in gingiva. Gingival involvement has been reported in only a very limited number of cases. A 13-year-old boy presented with gingival enlargement in the maxillary and mandibular anterior region associated with enlargement of lower lip with no systemic manifestations. He had a history of tuberculous lymphadenitis before 5 years which was inadequately treated. The patient's erythrocyte sedimentation rate was 70 mm/h. Histopathological report of the gingival lesion revealed noncaseating granulomas with nests of epithelioid cells and multinucleated Langhans giant cells. The patient was then referred to a physician for management, who initiated active antitubercular treatment following which the condition resolved. The aim of this article is to emphasize the importance of early diagnosis of primary TB of the gingiva which may be misdiagnosed when oral lesions are not associated with any apparent systemic infection.

  14. Gingival Prosthesis; An Alternative to Surgery in Multiple Site ...

    African Journals Online (AJOL)

    Y is a 26 year old male; Nigerian medical student who presented with a case IV localized gingival recession of the right mandibular central and lateral incisors. Miller's class II gingival recession on the lower left central and Miller's class III gingival recession on the lower left lateral incisor. The Miller's class IV localized ...

  15. Diverse modalities of gingival replacement: A report of three cases

    Directory of Open Access Journals (Sweden)

    Dileep N Vinnakota

    2012-01-01

    Full Text Available Gingival replacement is often a component of comprehensive prosthodontics. Gingival prostheses may be fixed or removable. It can be made from acrylics, composite resins, silicones or porcelain-based materials.This paper describes different clinical situations in which three types of gingival prostheses, removable acrylic veneer with melanin pigmentation, fixed ceramic veneer and flexible nylon based veneer, were used effectively.

  16. Gingival Recession in a Child‑Patient; Easily Missed Etiologies ...

    African Journals Online (AJOL)

    Gingival recession is commonly associated with plaque‑induced inflammation and calculus. A high frenal attachment is more important in gingival recession in the child‑patient. A healthy child‑patient with impeccable oral hygiene presented with localized gingival recession without plaque‑induced inflammation which led to ...

  17. Does any relationship exist between self reported gingival bleeding ...

    African Journals Online (AJOL)

    Individuals with gingival bleeding were significantly more likely to rate their dental and gingival health as fair/poor, use strong brushing stroke during tooth brushing and report worsening condition of teeth despite daily tooth brushing, express worry about the gingival color and less likely to be satisfied about the appearance ...

  18. Sangramiento gingival y flora bacteriana en la gingivitis y la periodontitis

    OpenAIRE

    Iriam Baldemira Rodríguez; Zaida T Iliasastigui Ortueta²; María E Acosta Navarro³

    1996-01-01

    Se estudiaron 30 sitios o áreas periodontales que presentaban gingivitis y 30 con periodontitis, con el objetivo de determinar la relación existente entre el sangramiento gingival y la flora microbiana presente en la gingivitis y la periodontitis. Los pacientes seleccionados no presentaban antecedentes de enfermedad general y no habían recibido medicación antimicrobiana ni tratamiento periodontal en los útimos 6 meses; en el caso de las mujeres, no podían estar embarazadas. En los dientes sel...

  19. Influencia del tratamiento quirúrgico de la próstata sobre la función renal en pacientes con insuficiencia renal crónica secundaria a hiperplasia prostática benigna

    Directory of Open Access Journals (Sweden)

    Roxana Aguirre Castañeda

    2002-07-01

    Full Text Available Objetivo: Evaluar la influencia del tratamiento quirúrgico sobre la función renal en pacientes con Insuficiencia Renal Crónica (IRC causada por Hiperplasia Prostática Benigna (HPB. Material y métodos: Es un estudio descriptivo, retrospectivo y analítico de series de casos; cuya variable resultado principal fue el delta de creatinina (creatinina post cirugía - creatinina pre-cirugía, los deltas de creatinina negativos se categorizaron como mejoría de la función renal y los deltas de creatinina positivos como deterioro de la función renal. Resultados: De 40 casos, 24 cumplían con los criterios de inclusión. La edad promedio fue de 67.2 ± 6.8 años. El síntoma más frecuente fue el chorro urinario delgado presentándose en 20 (83.3% pacientes. Trece(54.17% pacientes tuvieron una próstata mediana, quienes con los pacientes de próstata grande refirieron con mayor frecuencia el síntoma de polaquiuria (p=0.03. El tratamiento quirúrgico de pacientes con IRC por HPB produjo una mejoría de la función renal en el 83% de los casos. Solo 4(16.67% pacientes tuvieron delta de creatinina positivo con disminución de la función renal post-cirugía. Se encontró una correlación directa entre la edad y el delta de creatinina (r=0.55 (p=0.004 traduciendo una asociación del deterioro de la función renal post-cirugía con la edad. Conclusiones: El tratamiento quirúrgico de pacientes con IRC por HPB produjo una mejoría de la función renal en la mayoría de los pacientes evaluados en este estudio. No se identificó factores de riesgo relacionados con un deterioro o mejoría de la función renal post-cirugía. (Rev Med Hered 2002; 13: 99-104.

  20. Recesión gingival: una revisión de su etiología, patogénesis y tratamiento Gingival recession: a review of its aetiology, pathogenesis and treatment

    OpenAIRE

    C.M. Ardila Medina

    2009-01-01

    La recesión gingival describe la localización del margen gingival libre apical a la unión cemento esmalte; está asociada a estética indeseable, abrasión superficial radicular, sensibilidad y caries radicular. Reportes recientes indican que hay una prevalencia substancial en el aumento de las recesiones en diferentes poblaciones, incrementándose significativamente después de la quinta década. Uno de los objetivos de la terapia periodontal es corregir quirúrgicamente las recesiones, por esta ra...

  1. Descripción de lesiones pulmonares por Pseudalius inflexus en la marsopa Phocaena spinipinnis

    Directory of Open Access Journals (Sweden)

    Alfonso Chavera

    2011-05-01

    Full Text Available Se describen las lesiones pulmonares ocasionadas por el nematodo, Pseudalius inflexus (Rudolphi, 1808 Schneider, 1866 en dos especímenes, macho y hembra, de Phocoena spinipinnis Burmeisteir, 1865 "marsopa espinosa", capturados en aguas de la Reserva Nacional de Paracas, Perú. Macroscópicamente, los pulmones mostraron nódulos indurados superficiales de 0,5 - 2 cm de diámetro, donde al corte se encontraron nematodos rodeados por una severa reacción inflamatoria crónica y en los bronquios se observa que el extremo anterior de los parásitos obstruye la luz mientras que el extremo posterior se encuentra libre. Microscópicamente, los parásitos están en diferentes grados de degeneración, rodeados de un extenso exudado inflamatorio compuesto por eosinófilos, macrófagos, mononucleares, células gigantes multinucleadas con extenso tejido de granulación que infiltra el parénquima pulmonar, alvéolos distendidos y en algunos sectores destruidos. Además, se observa hiperplasia de mucosa bronquial, pared arterial con hiperplasia de capa muscular lisa, disminución del lumen. P. inflexus ocasiona una bronconeumonía crónica severa. Esta es la primera descripción de las lesiones pulmonares que produce P. inflexus en P. spinipinnis.

  2. Estudio celular y molecular en cultivos de fibroblastos tratados con fármacos inductores de agrandamiento gingival

    OpenAIRE

    Ramírez Rámiz, Albert

    2007-01-01

    El Agrandamiento gingival farmacológico -AGIF- es un dismorfismo gingival provocado por la inducción de fármacos antiepilépticos -Fenitoína-, antagonistas del calcio -Nifedipina- e inmunosupresores -Ciclosporina-. En los primeros casos de AGIF, se creía que la alteración histopatológica residía en un aumento de la población celular de los fibroblastos -Hipótesis nula-. Este estudio quiere demostrar que esta alteración se produce en la matriz extracelular -fibras colágenas y glicosaminoglicano...

  3. Aggressive Periodontitis with Streptococcal Gingivitis a Case Report

    Directory of Open Access Journals (Sweden)

    Gaurav Solanki

    2012-10-01

    Full Text Available Acute streptococcal gingivitis is an acute inflammation of the oral mucosa and also seen with the other oral diseases as aggressive periodontitis. Streptococcal infections of gingiva are seen rarely; also the origin of this gingival inflammation is occasionally different from that of routine plaque associated gingivitis. This case report describes a patient who presented with severe gingival inflammation and attachment loss that was diagnosed as an acute streptococcal infection associated with aggressive periodontitis. A case of aggressive periodontitis with streptococcal gingivitis was reported which was diagnosed treated with no postoperative complications.

  4. Sangramiento gingival y flora bacteriana en la gingivitis y la periodontitis

    Directory of Open Access Journals (Sweden)

    Iriam Baldemira Rodríguez

    1996-08-01

    Full Text Available Se estudiaron 30 sitios o áreas periodontales que presentaban gingivitis y 30 con periodontitis, con el objetivo de determinar la relación existente entre el sangramiento gingival y la flora microbiana presente en la gingivitis y la periodontitis. Los pacientes seleccionados no presentaban antecedentes de enfermedad general y no habían recibido medicación antimicrobiana ni tratamiento periodontal en los útimos 6 meses; en el caso de las mujeres, no podían estar embarazadas. En los dientes seleccionados se procedió a tomar la muestra cumpliendo con los requisitos establecidos; luego se examinó inmediatamente en el microscopio de campo oscuro. Los resultados obtenidos indican que no hubo relación entre los morfotipos microbianos y los diferentes valores del índice de sangramiento gingival.Thirty periodontal sites presenting with gingivitis and 30 with periodontitis were studied with the aim of determining the relation between gingival bleeding and microflora present in gingivitis and periodontitis. Patients selected for the study did not present with a history of systemic diseases and received neither antimicrobial medication nor periodontal treatment during the last 6 months, in the case of women it was required that they were not pregnant. The sample was taken in the teeth chosen in compliance with the requirements established; then the sample was immediately examined in the dark field microscope. Results obtained suggest that there was no relationship between microbial morphological types and the different values of the gingival bleeding index.

  5. [Gingival retraction paste versus gingival retraction cord for fixed prosthodontics: a systematic review].

    Science.gov (United States)

    Hong, Le-guan; Guo, Li-ping; Xue, Li-li

    2013-08-01

    To assess the efficacy of gingival retraction paste versus gingival retraction cord in fixed prosthodontics on gingiva protection, tooth preparation, clarity of the impression and plaster model, and aptness of the prosthesis. Chinese BioMedical Literature Database, VIP, China National Knowledge Infrastructure (CNKI) and Wangfang database were searched on November 15th 2012 for eligible studies. Hand-searching included references of the included studies and Chinese dental journals. Risk of bias of the included studies was assessed by 2 reviewers independently using Cochrane Collaboration's tool, and data extraction was done by the 2 reviewers. Meta analysis was performed with Revman 5.1 software. Nine randomized controlled trials, involving 1153 participants, were included. All of them had moderate risk of bias. Meta analysis revealed that gingival retraction paste had better effect on gingival health [RR=1.05, 95%CI (1.00, 1.11), P=0.04], tooth preparation [RR=1.17, 95%CI (1.07, 1.28), P=0.0008] and clarity of the impression and plaster model [RR=1.08, 95%CI (1.03, 1.13), P=0.0009] than gingival retraction cord, and the aptness of the prosthesis was as good as the cord [RR=1.07, 95%CI (0.96, 1.19), P=0.21]. The gingival retraction paste has better effect on gingival health, tooth preparation and clarity of the impression and plaster model, while the aptness of the prosthesis is as good as the cord and can be considered as a good candidate of the gingival retraction cord, but more randomized controlled trials are needed.

  6. Gingival evaluation of the pediatric cardiac patient.

    Science.gov (United States)

    Nosrati, Erez; Eckert, George J; Kowolik, Michael J; Ho, Jason G; Schamberger, Marcus S; Kowolik, Joan E

    2013-01-01

    Children with congenital cardiovascular diseases (CCDs) who suffer from dental diseases have an increased risk of infective endocarditis. In the light of recent evidence, oral inflammatory diseases may also increase the severity of their cardiovascular condition. The purpose of this study was to evaluate the gingival status of children with congenital cardiovascular diseases in comparison to healthy children. Fifty 7- to 13-year-old children were included. The test group comprised 25 CCD children subdivided into three groups: (1) unrepaired ventricular septal defect; (2) aortic valve stenosis; and (3) coarctation of the aorta. The control group consisted of 25 healthy age- and gender-matched children. Gingivitis, plaque, calculus, and recession were measured on six sites per tooth on 12 teeth. CCD children had significantly more gingivitis (P.02), and calculus (Pdiseases had a higher prevalence of periodontal disease, evidenced by gingivitis, plaque, calculus, and recession. These children should be evaluated periodontally and their oral health monitored on a 3-month basis to prevent disease development, benefit cardiovascular condition, prevent endocarditis, and improve quality and longevity of life.

  7. Gingival pigmentation (cause, treatment and histological preview

    Directory of Open Access Journals (Sweden)

    Rehab A. Abdel Moneim

    2017-06-01

    Full Text Available Facial appearance depends on several oral and extraoral factors. The gingiva is an important intraoral tissue which when affected particularly by pigmentation is mainly responsible for the unpleasant appearance. Several causes of gingival pigmentation were previously mentioned in text together with the possible techniques of treatment. In this review, we will focus on this topic with a histological point of view.

  8. Gingival Overgrowth and Associated Factors among Epileptic ...

    African Journals Online (AJOL)

    Bio-data and medical history were collected using a structured self-administered questionnaire and confirmed from patients' case file. Oral hygiene was assessed using the Simplified Oral Hygiene Index (S-OHI) of Green and Vermillion and GO, the New Clinical Index for Drug-Induced Gingival Overgrowth (DIGO). Result: ...

  9. Leukemic Gingival Enlargement - A Case Report

    Directory of Open Access Journals (Sweden)

    M Anupama

    2003-01-01

    Full Text Available Acute myeloid leukemia being a malignant neoplasm of the WBC series, has oral manifestations throughout the course of the disease. Since oral signs and symptoms arc so common, the dental surgeon may be the first to diagnose it" Here is a case report of leukemic gingival enlargement in a patient with typical clinical and oral manifestations of AML

  10. Prevention of gingivitis: Oral hygiene and dentifrices

    NARCIS (Netherlands)

    Sälzer, S.A.

    2016-01-01

    At the basis of Oral Health lies daily oral hygiene self-care with the result, if correctly performed, of plaque and gingivitis reduction. Epidemiological studies indicate that the level of oral hygiene in the general population has increased over the last decades. However, there still appears to be

  11. Association between gingivitis and anterior gingival enlargement in subjects undergoing fixed orthodontic treatment

    Directory of Open Access Journals (Sweden)

    Fabricio Batistin Zanatta

    2014-06-01

    Full Text Available OBJECTIVE: The aim of this study was to investigate the association among gingival enlargement (GE, periodontal conditions and socio-demographic characteristics in subjects undergoing fixed orthodontic treatment. METHODS: A sample of 330 patients undergoing fixed orthodontic treatment for at least 6 months were examined by a single calibrated examiner for plaque and gingival indexes, probing pocket depth, clinical attachment loss and gingival enlargement. Socio-economic background, orthodontic treatment duration and use of dental floss were assessed by oral interviews. Associations were assessed by means of unadjusted and adjusted Poisson's regression models. RESULTS: The presence of gingival bleeding (RR 1.01; 95% CI 1.00-1.01 and excess resin around brackets (RR 1.02; 95% CI 1.02-1.03 were associated with an increase in GE. No associations were found between socio-demographic characteristics and GE. CONCLUSION: Proximal anterior gingival bleeding and excess resin around brackets are associated with higher levels of anterior gingival enlargement in subjects under orthodontic treatment.

  12. Comparative Evaluation of Gingival Depigmentation using Tetrafluoroethane Cryosurgery and Gingival Abrasion Technique: Two Years Follow Up.

    Science.gov (United States)

    Kumar, Santhosh; Bhat, G Subraya; Bhat, K Mahalinga

    2013-02-01

    A comparative evaluation of the gingival depigmentation by using Tetrafluoroethane cryosurgery and the gingival abrasion technique - 2 years of follow up. Ten systemically healthy patients who were aged 18 to 36 years were selected for the study. Tetrafluoroethane was used for the cryosurgical depigmentation and the gingival abrasion technique used a coarse flame shaped bur. The presence or absence of pigmentation was tabulated, based on the GPI (Gingival Pigmentation Index). For the statistical analysis, Freidman's test was used. The keratinization was completed within a week after the application of the cryogen and about 10 days after the gingival abrasion technique was done. The statistical analysis which was done after 90th, 180th days and 2 years. The p-value which was obtained (pgingival abrasion. During the follow up period, no side effects were seen for both the techniques and the improved aesthetics was maintained upto 2 years. The use of cryogen Tetrafluoroethane is easy, practical and inexpensive as compared to gingival abrasion, due to its high rate of recurrence. Hence, it is more acceptable to the patients and the operator. Further studies are needed to assess the long term effectiveness of the cryosurgical method of depigmentation.

  13. Treatment of localized gingival recessions using gingival unit grafts: a randomized controlled clinical trial.

    Science.gov (United States)

    Kuru, Bahar; Yıldırım, Selin

    2013-01-01

    One of the success factors in periodontal plastic surgery is the synergistic relationship between involved tissues and vascular supply. Gingiva as a functional unit is unique with a specific vascular configuration and contains the supracrestal portion naturally created to survive over avascular root surfaces. The aim of this randomized controlled trial is to clinically evaluate the treatment of localized gingival recessions by using gingival unit grafts (palatal tissue involving marginal gingiva and papillae) compared with conventional palatal grafts. Seventeen patients with Class I to II recession defects on mandibular anterior teeth were included and randomly divided into two groups. Recessions were treated with gingival unit grafts in group 1 (n = 8) and with palatal grafts in group 2 (n = 9). Clinical parameters including vertical recession (VR), probing depth, keratinized tissue (KT), and attachment level were recorded at baseline and 8 months after surgery. Both treatments produced significant clinical improvements within the groups. Intergroup comparison revealed significantly higher VR reduction, attachment, and KT gain in group 1 than in group 2; mean percentages of the defect coverage were 91.62% ± 9.74% and 68.97% ± 13.67%, respectively (P <0.05). Healing of the gingival unit donor site was uneventful. Within its limits, this study demonstrates the possibility of treating buccal recessions with gingival unit grafts as an alternative technique using gingival donor graft of site-specific vascular configuration, with better defect coverage, clinical, and esthetic improvements compared with palatal grafts.

  14. Analysis of proliferative activity in oral gingival epithelium in immunosuppressive medication induced gingival overgrowth

    Directory of Open Access Journals (Sweden)

    Özdemir B Handan

    2006-05-01

    Full Text Available Abstract Background Drug-induced gingival overgrowth is a frequent adverse effect associated principally with administration of the immunosuppressive drug cyclosporin A and also certain antiepileptic and antihypertensive drugs. It is characterized by a marked increase in the thickness of the epithelial layer and accumulation of excessive amounts of connective tissue. The mechanism by which the drugs cause gingival overgrowth is not yet understood. The purpose of this study was to compare proliferative activity of normal human gingiva and in cyclosporine A-induced gingival overgrowth. Methods Gingival samples were collected from 12 generally healthy individuals and 22 Cyclosporin A-medicated renal transplant recipients. Expression of proliferating cell nuclear antigen was evaluated in formalin-fixed, paraffin-embedded gingival samples using an immunoperoxidase technique and a monoclonal antibody for this antigen. Results There were differences between the Cyclosporin A group and control group in regard to proliferating cell nuclear antigen and epithelial thickness. In addition, the degree of stromal inflammation was higher in the Cyclosporin A group when compared with the control group. Conclusion The results suggest that the increased epithelial thickness observed in Cyclosporin A-induced gingival overgrowth is associated with increased proliferative activity in keratinocytes.

  15. Spontaneous improvement of gingival recession after correction of tooth positioning.

    Science.gov (United States)

    Machado, Andre Wilson; MacGinnis, Matthew; Damis, Lucio; Moon, Won

    2014-06-01

    A 30-year-old woman sought treatment for malpositioned mandibular incisors; the roots were positioned outside the alveolar bone, related to severe localized gingival recession. She had been previously treated orthodontically and subsequently underwent 2 gingival grafts. The new treatment included torquing the roots back within the alveolar bone and referral to a periodontist for a gingival graft. In this clinical report, the possible spontaneous improvement of gingival recession is discussed. A hypothesis described in the literature is called the "creeping attachment" phenomenon. The literature includes conflicting reports about the cause-and-effect relationship between orthodontics and gingival recession. This clinical example reports spontaneous improvement of gingival recession after correction of tooth positioning in the alveolar bone. A gingival graft can be performed after adequate root positioning in the alveolar bone housing, thus increasing the chance of achieving more favorable results. Copyright © 2014 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  16. Chlorhexidine mouthwash plaque levels and gingival health.

    Science.gov (United States)

    Richards, Derek

    2017-06-23

    Data sourcesCochrane Oral Health's Trials Register; Cochrane Central Register of Controlled Trials (CENTRAL) Medline; clinicaltrials.gov and the World Health Organization International Clinical Trials Registry Platform. There were no language or date restrictions on searches.Study selectionRandomised controlled trials (RCTs) assessing the effects of chlorhexidine mouthrinse used as an adjunct to mechanical oral hygiene procedures for at least four weeks on gingivitis in children and adults.Data extraction and synthesisTwo reviewers independently abstracted data and assessed risk of bias. Mean and standardised mean differences were used for continuous outcomes and risk ratios for dichotomous outcomes. Meta-analysis was carried out where studies of similar comparisons reported the same outcomes at the same time interval.ResultsFifty-one RCTs involving a total of 5,345 patients were included. Only one study was at low risk of bias, the other 50 were at high risk. For patients with mild gingivitis (gingival index [GI] 0 to 3 scale) four to six weeks' use of chlorhexidine mouthrinse reduced gingivitis by 0.21 (95% CI; 0.11 to 0.31) with a similar effect at six months. There were insufficient data to assess the effect on patients with moderate or severe gingival inflammation. For plaque there was a larger effect in favour of chlorhexidine mouthrinse at four to six weeks, SMD (standardised mean difference) = -1.45 (95% CI; -1.90 to -1.00), with a similarly large reduction at six months. A large increase in extrinsic tooth staining was seen with chlorhexidine use at four to six weeks, SMD = 1.07 (95%CI; 0.80 to 1.34) and seven to twelve weeks and six months. A range of other adverse effects were reported including taste disturbance/alteration, oral mucosa symptoms including soreness, irritation, mild desquamation and mucosal ulceration/erosions, and a general burning sensation or a burning tongue or both.ConclusionsThere is high quality evidence from studies that reported

  17. Relación del residuo post-miccional, grado de "trabeculación" vesical y el flujo urinario en pacientes con hiperplasia prostática benigna sintomática.

    Directory of Open Access Journals (Sweden)

    Humberto Condori

    2012-07-01

    Full Text Available Objetivo: Determinar la relación entre el grado de "trabeculación" vesical, el residuo pos miccional y el grado de obstrucción al flujo de salida urinario en pacientes con hiperplasia benigna de próstata (HBP sintomática. Material y métodos: Serie de casos analítico y retrospectivo que incluyó 37 pacientes con HBP sintomática atendidos ambulatoriamente en el servicio de Urología del Hospital Nacional Cayetano Heredia en el 2009. El grado de "trabeculación" vesical se determinó por cistoscopia, el residuo vesical post-miccional por ecografía y el grado de obstrucción mediante uroflujometría. Resultados: La edad de los pacientes fue: 68,2 ± 7,9 (50-83 años. Los valores del volumen prostático, porcentaje de residuo post-miccional y el flujo máximo fueron: 46,4 ± 20,6 cc (20-113; 33,4% ± 20,7 (5- 80 y 6,7 ± 2,12 7 ml/seg (3-10, respectivamente. No se encontró correlación entre: el porcentaje de residuo post-miccional y el flujo urinario máximo (rs = -0,07; p=0,67 y entre el volumen prostático y el flujo máximo con (rs= 0,05; p= 0,7. Tampoco se encontró concordancia entre el grado de "trabeculación" vesical y el flujo máximo (Kappa= 0,0034; p=0,5 y entre el porcentaje de residuo post-miccional y el grado de "trabeculación" (Kappa= 0,18; p=0,06. Conclusión: No se encontró relación entre el flujo máximo urinario, el porcentaje de residuo post-miccional y el grado de "trabeculación", en pacientes con HBP sintomática.

  18. Nueva mutación heterocigota en el gen de la proteína regulatoria aguda de la esteroideogénesis (StAR en un paciente 46,XY con hiperplasia adrenal congénita lipoidea

    Directory of Open Access Journals (Sweden)

    María Sonia Baquedano

    2013-08-01

    Full Text Available StAR forma parte del complejo multiproteico transduceosoma, encargado del transporte de colesterol y que facilita su entrada a la mitocondria. Mutaciones recesivas en el gen STAR causan formas clásicas y no clásicas de hiperplasia adrenal congénita lipoidea. Analizamos las consecuencias moleculares de una nueva mutación heterocigota en STAR en un paciente 46,XY con genitales ambiguos e insuficiencia adrenal. Hallamos un cambio heterocigota de novo, IVS1-2A>G, en el gen STAR y el polimorfismo heterocigota, pG146A, en SF1. No se detectaron mutaciones en los genes CYP11A1, FDX1 y FDXR, VDAC1 y TSPO. Por RT-PCR y secuenciación se observó un transcripto-exón2 y el transcripto normal (WT de StAR, a partir del ARN de tejido gonadal del paciente. Se detectó el precursor (37 kD y la proteína StAR madura (30 kD en células COS-7 transfectadas con el plásmido mutante y WT. Por inmunofluorescencia la observación de co-localización de la proteína mutante (p.G22_L59delStAR en mitocondrias fue casi nula. La actividad de p.G22_L59delStAR fue del 65% ± 13 respecto del WT. La co-transfección de los plásmidos p.G22_L59delStAR y WT redujo la actividad de WT en 62.0 ± 13.9%. La mutación IVS1-2A>G provocó la pérdida de los aminoácidos 22 a 59 en la secuencia mitocondrial N-terminal. Postulamos que ello conduciría a un plegamiento anormal de la proteína que alteraría su procesamiento y translocación. La proteína mutante p.G22_L59delStAR podría interferir con la acción de la proteína StAR WT bloqueando el complejo transduceosoma y causando una forma dominante de deficiencia de StAR, que explicaría el fenotipo clínico en heterocigosis.

  19. Aloe vera: It's effect on gingivitis.

    Science.gov (United States)

    Ajmera, Neha; Chatterjee, Anirban; Goyal, Vikas

    2013-07-01

    Aloe vera is the oldest medicinal plant that has maintained its popularity over the course of time. It is widely known for its medicinal uses in wound healing, as an analgesic, and for its anti-inflammatory properties. The aim of this study is to evaluate the anti-inflammatory property of aloe vera mouthwash on plaque-induced gingivitis. Forty-five patients who were diagnosed with plaque-induced gingivitis were included in the study. They were divided into three groups with fifteen patients in each group. Group 1 was asked to rinse with 10 ml of aloe vera mouthwash twice daily for three months. Group 2 were treated with scaling only. Group 3 patients were asked to rinse with aloe vera mouthwash and scaling was done. The clinical changes were evaluated with Loe and Silness gingival index (1963) and Muhlemann and Son's Sulcus bleeding index (1971) at baseline, after one month and three months, respectively. The data obtained was compared statistically. The paired 't' test was done for intragroup comparison and one-way analysis of variance with a post hoc Tukey test was used for intergroup comparison. The data was obtained at the baseline, end of first month, and end of the third month. The result suggested reduction in gingival inflammation in all the three groups, but it was more in the aloe vera mouthwash and scaling group. Hence, it was concluded that aloe vera had a significant anti-inflammatory property. Thus, it can be used as an adjunct to mechanical therapy for treating plaque-induced gingivitis.

  20. Hiperplasia angiolinfoide con eosinofilia: a propósito de una localización atípica en músculo trapecio

    OpenAIRE

    Sangüesa, M. J.; Cabanes, F.; Fernández Gabarda, Rafael; Villanueva García, E.; Terradez, J. J.; Valverde, C.

    2009-01-01

    La hiperplasia angiolinfoide con eosinofilia es una patología poco frecuente de presentación clínica inespecífica que lleva a que rara vez se diagnostique antes del estudio histológico. Habitualmente afecta a piel y tejido celular subcutáneo siendo rara la localización extracutánea. Presentamos un caso clínico de una tumoración en una mujer de 46 años localizada a nivel del músculo trapecio; y revisamos las características histopatológicas y de tratamiento de esta patología. An...

  1. Hiperplasia supra-renal congênita por deficiência de 11-ß-hidroxilase Congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency

    Directory of Open Access Journals (Sweden)

    Ramires Tosatti Júnior

    2005-12-01

    Full Text Available Este artigo tem o objetivo de relatar o diagnóstico e a evolução clínica de um paciente de 15 anos portador de uma disfunção congênita da esteroideogênese adrenal, que pode apresentar-se como hipertensão arterial de diagnóstico muitas vezes tardio (adolescência, virilização ou formas perdedoras de sal (nascimento e infância.The objective of this article is to relate the diagnostic and clinical evolution of a 15 year old patient with a congenital adrenal steroidogenesis dysfunction that can present as hypertension diagnosed later in life (adolescence, virilization or salt wasting (birth and childhood.

  2. El níquel y su vínculo con el agrandamiento gingival: revisión de la literatura

    OpenAIRE

    V. Gómez Arcila; L. Fang Mercado; A. Herrera Herrera; Díaz Caballero

    2014-01-01

    El agrandamiento gingival es común entre los pacientes y puede ser causado por una variedad de factores etiológicos. La razón más común es la inflamación gingival provocada por mala higiene oral y alta carga bacteriana. Otros factores implicados son los medicamentos sistémicos, en donde se encuentran bloqueadores de los canales de calcio, inmunosupresores y anticonvulsivantes. Algunos crecimientos gingivales podrían estar asociados a condiciones hormonales como la pubertad, el embarazo o la d...

  3. Primary prevention of periodontitis: managing gingivitis.

    Science.gov (United States)

    Chapple, Iain L C; Van der Weijden, Fridus; Doerfer, Christof; Herrera, David; Shapira, Lior; Polak, David; Madianos, Phoebus; Louropoulou, Anna; Machtei, Eli; Donos, Nikos; Greenwell, Henry; Van Winkelhoff, Ari J; Eren Kuru, Bahar; Arweiler, Nicole; Teughels, Wim; Aimetti, Mario; Molina, Ana; Montero, Eduardo; Graziani, Filippo

    2015-04-01

    Periodontitis is a ubiquitous and irreversible inflammatory condition and represents a significant public health burden. Severe periodontitis affects over 11% of adults, is a major cause of tooth loss impacting negatively upon speech, nutrition, quality of life and self-esteem, and has systemic inflammatory consequences. Periodontitis is preventable and treatment leads to reduced rates of tooth loss and improved quality of life. However, successful treatment necessitates behaviour change in patients to address lifestyle risk factors (e.g. smoking) and, most importantly, to attain and sustain high standards of daily plaque removal, lifelong. While mechanical plaque removal remains the bedrock of successful periodontal disease management, in high-risk patients it appears that the critical threshold for plaque accumulation to trigger periodontitis is low, and such patients may benefit from adjunctive agents for primary prevention of periodontitis. The aims of this working group were to systematically review the evidence for primary prevention of periodontitis by preventing gingivitis via four approaches: 1) the efficacy of mechanical self-administered plaque control regimes; 2) the efficacy of self-administered inter-dental mechanical plaque control; 3) the efficacy of adjunctive chemical plaque control; and 4) anti-inflammatory (sole or adjunctive) approaches. Two meta-reviews (mechanical plaque removal) and two traditional systematic reviews (chemical plaque control/anti-inflammatory agents) formed the basis of this consensus. Data support the belief that professionally administered plaque control significantly improves gingival inflammation and lowers plaque scores, with some evidence that reinforcement of oral hygiene provides further benefit. Re-chargeable power toothbrushes provide small but statistically significant additional reductions in gingival inflammation and plaque levels. Flossing cannot be recommended other than for sites of gingival and periodontal

  4. Distribution of smile line, gingival angle and tooth shape among the Saudi Arabian subpopulation and their association with gingival biotype.

    Science.gov (United States)

    AlQahtani, Nabeeh A; Haralur, Satheesh B; AlMaqbol, Mohammad; AlMufarrij, Ali Jubran; Al Dera, Ahmed Ali; Al-Qarni, Mohammed

    2016-04-01

    To determine the occurrence of smile line and maxillary tooth shape in the Saudi Arabian subpopulation, and to estimate the association between these parameters with gingival biotype. On the fulfillment of selection criteria, total 315 patients belong to Saudi Arabian ethnic group were randomly selected. Two frontal photographs of the patients were acquired. The tooth morphology, gingival angle, and smile line classification were determined with ImageJ image analyzing software. The gingival biotype was assessed by probe transparency method. The obtained data were analyzed with SPSS 19 (IBM Corporation, New York, USA) software to determine the frequency and association between other parameters and gingival biotype. Among the clinical parameters evaluated, the tapering tooth morphology (56.8%), thick gingival biotype (53%), and average smile line (57.5%) was more prevalent. The statistically significant association was found between thick gingival biotype and the square tooth, high smile line. The high gingival angle was associated with thin gingival biotype. The study results indicate the existence of an association between tooth shape, smile line, and gingival angle with gingival biotype.

  5. Increase in gingival inflammation under academic stress.

    Science.gov (United States)

    Deinzer, R; Rüttermann, S; Möbes, O; Herforth, A

    1998-05-01

    Several correlational questionnaire studies have observed a positive relationship between psychological stress and periodontal diseases. This paper analyses the effects of academic stress on periodontal health in a prospective quasi-experimental design. 26 medical students participating in a major exam and the same number of medical students not participating in any exam throughout the study period volunteered for the study. Bleeding on probing was assessed 4 weeks prior to the exam period (baseline) and at the last day of the exam. Severe deterioration in gingival health from baseline to the last exam day were observed more frequently in exam students than in controls (p=0.014). 6 exam students but only 1 control person developed a severe gingivitis at at least one formerly healthy tooth throughout the study period. These results further support the hypothesis that psychological stress is a significant risk factor for periodontal inflammation. Future studies should examine factors mediating this relationship.

  6. Necrotising Ulcerative Gingivitis: A Literature Review.

    Science.gov (United States)

    Dufty, James; Gkranias, Nikolaos; Donos, Nikos

    2017-01-01

    The literature surrounding necrotising ulcerative gingivitis (NUG) is extensive, yet the rare nature of this disease means that there is a lack of good quality research available. This paper aims to scrutinise the literature and provide an up-to-date summary of the available information. A literature search was performed electronically using the Cochrane Library, Ovid Medline, Embase, PubMed Clinical Queries and Google Scholar. Keyword searches were carried out, utilising MeSH terms and free text. English language articles primarily were included, with key foreign language (French and German) articles included where possible from the 1900s to the present day. Necrotising ulcerative gingivitis is a rare disease (prevalence importance should not be underestimated as one of the most severe responses to the oral biofilm. Risk factors must be investigated and addressed. Treatment should consist of gentle superficial debridement, oral hygiene instruction and prescription of mouthwash and antibiotics in severe cases.

  7. Chronic Inflammatory Gingival Overgrowths: Laser Gingivectomy & Gingivoplasty

    Science.gov (United States)

    Shankar, B Shiva; T, Ramadevi; S, Neetha M; Reddy, P Sunil Kumar; Saritha, G; Reddy, J Muralinath

    2013-01-01

    It is quite common to note chronic inflammatory Gingival overgrowths during and/or post orthodontic treatment. Sometimes the overgrowths may even potentially complicate and/or interrupt orthodontic treatment. With the introduction of soft tissue lasers these problems can now be addressed more easily. Amongst many LASERS now available in Dentistry DIODE LASERS seem to be most ideal for orthodontic soft tissue applications. As newer treatments herald into minimally invasive techniques, DIODE LASERS are becoming more promising both in patient satisfaction and dentist satisfaction. How to cite this article: Shankar BS, Ramadevi T, Neetha M S, Reddy P S K, Saritha G, Reddy J M. Chronic Inflammatory Gingival Overgrowths: Laser Gingivectomy & Gingivoplasty. J Int Oral Health 2013; 5(1):83-87. PMID:24155582

  8. Familial gingival fibromatosis: A rare case report

    Directory of Open Access Journals (Sweden)

    Shweta Sharma

    2012-01-01

    Full Text Available Hereditary gingival fibromatosis is a rare condition that can occur as an isolated disease or as part of a syndrome or chromosomal abnormality. In severe cases, the gingival enlargement may cover the crowns of teeth and cause severe functional and aesthetic concerns. Here, we present a case of an 8-year-old girl with severe enlargement of gums in maxilla and mandible. Both deciduous and permanent teeth were not erupted in the oral cavity at all. Mutation in the Son-of-Sevenless (SOS-1 gene has been associated with the disease. The diagnosis was made based on clinical examination and family history. Surgical removal of the hyperplastic tissue was performed under general anesthesia.

  9. Prevalence of gingival fibrous nodule in South Indians

    Directory of Open Access Journals (Sweden)

    Srikanth H Srivathsa

    2015-01-01

    Full Text Available Aims and Objectives: Gingival fibrous nodule is considered a normal variant of oral mucosa. So far no studies have been done to determine the prevalence and other characteristics of this entity. Hence, this study was taken up to study the prevalence of gingival fibrous nodule is south Indians. Materials and Methods: This clinical study consisted of 4642 adult subjects who were examined for the presence of gingival fibrous nodules. The age range of the subjects was 10-89 years. The study consisted of 2818 males and 1824 females. Results: One hundred and forty-five gingival fibrous nodules were identified in 128 individuals with a prevalence of 2.75%. They were predominant in males, in the mandibular anterior region. Multiple gingival fibrous nodules were more common than solitary form. Conclusion: This study demonstrates the prevalence of gingival fibrous nodules in south Indians.

  10. Treatment of gingival pigmentation : A case series

    Directory of Open Access Journals (Sweden)

    Prasad Deepak

    2005-01-01

    Full Text Available A smile expresses a feeling of joy, success, sensuality, affection and courtesy, and reveals self confidence and kindness. The harmony of the smile is determined not only by the shape, the position and the color of the teeth but also by the gingival tissues. Gingival health and appearance are essential components of an attractive smile. Gingival pigmentation results from melanin granules, which are produced by melanoblasts. The degree of pigmentation depends on melanoblastic activity. Although melanin pigmentation of the gingiva is completely benign and does not present a medical problem, complaints of ′black gums′ are common particularly in patients having a very high smile line (gummy smile. For depigmentation of gingiva different treatment modalities have been reported like- Bur abrasion, scraping, partial thickness flap, cryotherapy, electrosurgery and laser. In the present case series bur abrasion, scraping, partial thickness flap (epithelial excision cryotherapy and electrosurgery have been tried for depigmentation, which are simple, effective and yield good results, along with good patient satisfaction. The problems encountered with some of these techniques have also been discussed.

  11. Treatment of gingival pigmentation: a case series.

    Science.gov (United States)

    Deepak, Prasad; Sunil, S; Mishra, R; Sheshadri

    2005-01-01

    A smile expresses a feeling of joy, success, sensuality, affection and courtesy, and reveals self confidence and kindness. The harmony of the smile is determined not only by the shape, the position and the color of the teeth but also by the gingival tissues. Gingival health and appearance are essential components of an attractive smile. Gingival pigmentation results from melanin granules, which are produced by melanoblasts. The degree of pigmentation depends on melanoblastic activity. Although melanin pigmentation of the gingiva is completely benign and does not present a medical problem, complaints of 'black gums' are common particularly in patients having a very high smile line (gummy smile). For depigmentation of gingiva different treatment modalities have been reported like- Bur abrasion, scraping, partial thickness flap, cryotherapy, electrosurgery and laser. In the present case series bur abrasion, scraping, partial thickness flap (epithelial excision) cryotherapy and electrosurgery have been tried for depigmentation, which are simple, effective and yield good results, along with good patient satisfaction. The problems encountered with some of these techniques have also been discussed.

  12. Rare Gingival Metastasis by Hepatocellular Carcinoma

    Directory of Open Access Journals (Sweden)

    Li-Jun Xue

    2017-01-01

    Full Text Available Hepatocellular carcinoma (HCC uncommonly metastasizes to the gingiva, which always means a poor outcome. We reported a rare HCC case with multiple metastases to gingiva, lungs, and brain. A 60-year-old man was initially diagnosed as HCC with metastases to double lungs. He was subjected to a transarterial chemoembolization (TACE (5-fluorouracil, 750 mg and two cycles of intravenous chemotherapy (gemcitabine 1.8 g at days 1 and 8, oxaliplatin 200 mg at day 2, every 4 weeks. However, the volume of liver tumor still increased. A bean-size gingival nodule growing with occasional bleeding was also found. TACE (5-fluorouracil 750 mg, perarubicin 40 mg, cisplatin 20 mg was performed again and an oral sorafenib therapy (400 mg, twice per day was adopted. The disease maintained relatively stable for about 6 months until a second obvious progress. The gingival nodule was then palliatively excised and identified as a poorly differentiated metastatic HCC by histopathological examination. Best supportive treatments were made since the performance score was too bad. Finally, cerebral metastases occurred and the patient died of systemic failure. Upon review of previous reports, we discussed risk factors, clinical and pathological characteristics, treatments, and prognosis of gingival metastasis by HCC.

  13. Efectividad del uso tópico de Salvia officinalis en la disminución del índice gingival en sujetos con gingivitis Effectiveness of topical use of Salvia officinalis in the gingival index decrease in subjects with gingivitis

    Directory of Open Access Journals (Sweden)

    R Valenzuela Melgarejo

    2011-12-01

    Full Text Available Introducción: La gingivitis es el problema periodontal de mayor prevalencia en la población, por lo que deben buscarse más alternativas de tratamiento y prevención. Objetivo: Evaluar efecto del uso de Salvia officinalis en disminución del índice gingival modificado (IG en alumnos de Odontología de la Universidad del Desarrollo diagnosticados con gingivitis, año 2010. Sujetos y Método: Fue realizado un estudio cuantitativo, ciego, experimental del tipo ensayo clínico controlado con placebo, sobre la acción de extracto de S. officinalis en dentífrico y colutorios para gingivitis inducida por placa bacteriana, en 33 alumnos de odontología de la Universidad del Desarrollo, Concepción; 13 mujeres y 20 hombres entre 21 y 29 años. Fueron divididos en tres grupos; placebo, colutorio y dentífrico. Luego del inicio del tratamiento fueron citados a los 7, 14 y 28 días, finalizando el tratamiento el día 14. Resultados: En el control no se encontró diferencias significativas (p=0.061 la primera semana, mientras que en los grupos con colutorio o dentífrico si hubo diferencias significativas (p=0.000 y p=0.002. La última semana al retirar el placebo, el IG se mantuvo, por otro lado en los grupos con S. officinalis no continuó el descenso. La disminución del IG fue mayor para los grupos colutorio y dentífrico que para el control. Discusión: El uso de S. officinalis es efectivo en la disminución del IG. El colutorio y dentífrico logran disminuir con mayor rapidez el IG. El colutorio logró la mayor disminución del IG.Background: Gingivitis is the most prevalent periodontal problem in people, so we need to find new alternatives for treatment and prevention. Aim: To evaluate the effects of Salvia officinalis in the declining modified gingival index (GI in dentistry students of the Universidad del Desarrollo diagnosed with gingivitis, year 2010. Subjects and Methods: This was a quantitative study, blinded, experimental type of placebo

  14. Salivary biomarkers associated with gingivitis and response to therapy.

    Science.gov (United States)

    Syndergaard, Ben; Al-Sabbagh, Mohanad; Kryscio, Richard J; Xi, Jing; Ding, Xiuhua; Ebersole, Jeffrey L; Miller, Craig S

    2014-08-01

    Salivary biomarkers are potentially important for determining the presence, risk, and progression of periodontal disease. However, clinical translation of biomarker technology from lab to chairside requires studies that identify biomarkers associated with the transitional phase between health and periodontal disease (i.e., gingivitis). Eighty participants (40 with gingivitis, 40 healthy) provided saliva at baseline and 7 to 30 days later. An additional sample was collected from gingivitis participants 10 to 30 days after dental prophylaxis. Clinical parameters of gingival disease were recorded at baseline and the final visit. Salivary concentrations of interleukin (IL)-1β, IL-6, matrix metalloproteinase (MMP)-8, macrophage inflammatory protein (MIP)-1α, and prostaglandin E2 (PGE2) were measured. Clinical features of health and gingivitis were stable at both baseline visits. Participants with gingivitis demonstrated significantly higher bleeding on probing (BOP), plaque index (PI), and gingival index (GI) (P ≤0.002) and a significant drop in BOP, PI, and GI post-treatment (P ≤0.001). Concentrations of MIP-1α and PGE2 were significantly higher (2.8 times) in the gingivitis group than the healthy group (P ≤0.02). After dental prophylaxis, mean biomarker concentrations did not decrease significantly from baseline in the gingivitis group, although concentrations of IL-1β, IL-6, and MMP-8 approached healthy levels, whereas MIP-1α and PGE2 concentrations remained significantly higher than in the healthy group (P ≤0.04). Odds ratio analyses showed that PGE2 concentrations, alone and in combination with MIP-1α, readily discriminated gingivitis from health. Salivary PGE2 and MIP-1α discriminate gingivitis from health, and patients with gingivitis who return to clinical health continue to produce inflammatory mediators for weeks after dental prophylaxis.

  15. Primary cell culture from human oral tissue: gingival keratinocytes,gingival fibroblasts and periodontal ligament fibroblasts

    Directory of Open Access Journals (Sweden)

    Supreya Wanichpakorn

    2010-08-01

    Full Text Available Primary cell culture of human oral tissue has many applications for oral biology research. There are two techniques in primary culture, which includes the enzymatic and direct explant technique. The objectives of this study were (1 to isolate and investigate the difference in percentage the success in culturing three cell types from human oral tissue: gingival keratinocytes, gingival fibroblasts and periodontal ligament fibroblasts by using the direct explant technique; (2 to compare the effect of sex and age on the success of tissue culturing. Twenty seven tissue samples were obtained from healthy human gingival tissue, 19 female and 8 male patients aged 14-67 years (37.7±17.5. The tissue was cut into 1x1 mm pieces and placed on plastic culture plates containing Dulbecco’s Modified Eagle’s Medium supplemented with 10% fetal calf serum, 100 U/ml penicillin, 100 µg/ml streptomycin and 1% amphotericin B. For the keratinocytes culture, after the epithelial cells started to multiply around the gingival origin and the diameter was 2-5 mm., the fibroblasts were liminated by mechanical removal under inverted microscope to prevent fibroblast overgrowth and the medium was changed to keratinocyte-SFM (Gibco, BRL supplemented with 5 µg/ml gentamycin. The results revealed that gingival fibroblast gave the highest success rate in culture (96.3%, followed by gingival keratinocytes (88.9% and periodontal ligament fibroblasts (81.5%. There was no significant difference in the success rate of cultivation between younger and older individuals, as between sex of the subjects (p>0.05. The risk of failure in culture techniques is mainly caused by microbiological contamination from the tissue samples.

  16. Quantificação volumétrica da hiperplasia neointimal em artérias ilíacas após implante de suporte intravascular metálico Volumetric assessment of neointimal hyperplasia in iliac arteries after metal stent implantation

    Directory of Open Access Journals (Sweden)

    Samuel Martins Moreira

    2009-08-01

    Full Text Available OBJETIVO: Quantificar a hiperplasia neointimal em artérias ilíacas após stent, correlacionando fatores clínicos, arteriais e materiais dos stents. MATERIAIS E MÉTODOS: De junho de 2003 a agosto de 2005, 60 pacientes realizaram angioplastia transluminal percutânea e stent. Desses, 30 foram reestudados com ultrassonografia intravascular. Os dados foram analisados no laboratório de análise quantitativa. RESULTA-DOS: Dezesseis pacientes eram do sexo masculino (53,3% e 14 (46,7%, do sexo feminino. A média de idade foi de 60,3 anos. Apresentaram hipertensão arterial 22 pacientes (73,3%, tabagismo, 18 (62,1%, hiperlipidemia, 20 (66,7%, e diabetes, 9 (30%. Foram implantados 20 stents de nitinol (66,7% e 10 de aço inoxidável (33,3%. Quatro pacientes eram TASC A (13,3%, 15 eram TASC B (50% e 11, TASC C (36,7%. O volume da hiperplasia variou de 49,02 mm³ a 112,87 mm³ (média de 80,33 mm³. O percentual de obstrução intra-stent variou de 18% a 47% (média de 27,4%. Os resultados clínicos obtidos com stent se mantiveram até o reestudo. CONCLUSÃO: A hiperplasia neointimal sempre ocorre após a angioplastia transluminal percutânea e stent, porém os percentuais de obstrução não foram superiores a 50% em nenhum caso. Não houve diferença estatisticamente significante dos percentuais de obstrução intra-stent quanto aos materiais dos stents, aos fatores clínicos e aos fatores arteriais.OBJECTIVE: To quantify neointimal hyperplasia in iliac arteries after stent implantation, correlating clinical, arterial factors and stent material. MATERIALS AND METHODS: In the period from June/2003 to August/ 2005, 60 patients were submitted to percutaneous transluminal angioplasty and stenting. Among these patients, 30 were followed-up with intravascular ultrasonography. Data were analyzed in a laboratory of quantitative analysis by means of a specific software. RESULTS: Sixteen (53.3% patients were men, and 14 (46.7%, women, and the mean age was 60

  17. Prevalence of gingival biotype and its relationship to dental malocclusion.

    Science.gov (United States)

    Zawawi, Khalid H; Al-Harthi, Shaimaa M; Al-Zahrani, Mohammad S

    2012-06-01

    To study the prevalence of different gingival biotypes in a sample of patients and the association between gingival biotype and different dental malocclusions. Two hundred adult patients (100 males and 100 females) who presented for treatment at the Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia were recruited from February 2011 to February 2012. Gingival thickness was assessed for the maxillary central incisors using the transparency of periodontal probe technique. Angle's classification of malocclusion and smoking habit were also recorded. The mean age was 32.1 (+/-11.0) years. Thin gingival biotype was observed in 44.5% of the sample, of which 64% were females and 25% were males (p=0.001). Only 31.4% of current smokers had thin gingival biotype compared to 51.9% of subjects who never smoked (p=0.011). No significant association between dental malocclusions and the presence of thin gingival biotype was found (Class I = 42.9%, Class II = 44.1%, and Class III 53.9%, p=0.6). A high prevalence of thin gingival biotype especially among females was observed. Smokers had thicker gingival biotype. No relationship was found between gingival biotypes and Angle's classification of malocclusion.

  18. Gingivitis and salivary osmolality in children with cerebral palsy.

    Science.gov (United States)

    Santos, Maria Teresa Botti Rodrigues; Ferreira, Maria Cristina Duarte; Guaré, Renata Oliveira; Diniz, Michele Baffi; Rösing, Cassiano Kuchenbecker; Rodrigues, Jonas Almeida; Duarte, Danilo Antonio

    2016-11-01

    To investigate the influence of salivary osmolality on the occurrence of gingivitis in children with cerebral palsy (CP). A total of 82 children with spastic CP were included in this cross-sectional study. Oral motor performance and gingival conditions were evaluated. Unstimulated saliva was collected using cotton swabs, and salivary osmolality was measured using a freezing point depression osmometer. Spearman's coefficient, receiver operating characteristic (ROC), and multiple logistic regression analyses were performed. Strong correlation (r > 0.7) was determined among salivary osmolality, salivary flow rate, visible plaque, dental calculus, and the occurrence of gingivitis. The area under the ROC to predict the influence of salivary osmolality on the occurrence of gingivitis was 0.88 (95% CI 0.81-0.96; P gingivitis was 22.5%, whereas for the group presenting osmolality >84.5 mOsm/kgH2 O, the proportion of children with gingivitis was 77.5%. Salivary osmolality above 84.5 increased the likelihood of gingivitis fivefold, whereas each additional 0.1 mL of salivary flow reduced the likelihood of gingivitis by 97%. Gingivitis occurs more frequently in children with CP showing increased values of salivary osmolality. © 2016 BSPD, IAPD and John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  19. The effects of anabolic androgenic steroid abuse on gingival tissues.

    Science.gov (United States)

    Ozcelik, Onur; Haytac, M Cenk; Seydaoglu, Gulsah

    2006-07-01

    Anabolic androgenic steroid (AAS) is the familiar name for synthetic derivatives of the male sex hormone, testosterone. A large number of young adults abuse AAS to enhance performance and physical appearance. The aim of this study was to evaluate the effects of AAS abuse on the gingival tissues in a group of bodybuilders and weight lifters. The test group was composed of 24 athletes aged between 17 and 29 years who had been using AAS for >1 year. All subjects were clinically examined for plaque levels (plaque index), gingival inflammation (gingival index), and gingival enlargement. The results were compared to a control group of 20 bodybuilders who had never used AAS drugs and who matched for age, educational level, and oral habits according to the data obtained from the test group. Although there were no statistical differences between the plaque index (P>0.05) and gingival index (P>0.05) scores of the study group and the control group, the AAS abusers had statistically higher scores of gingival thickness, extent of gingival encroachment, and total gingival enlargement scores (Psports seem to increase despite legislation, dentists and periodontists should be familiar with the adverse effects of these synthetic derivatives of testosterone on the gingival tissues.

  20. [Clinical study on the effect of anti-gingivitis IgY toothpaste in control of gingivitis and dental plaque].

    Science.gov (United States)

    Zhang, Wei; Feng, Xi-Ping; Tao, Dan-Ying; Chen, Jian-Fen

    2016-08-01

    To observe the effect of anti-gingivitis IgY toothpaste in control of gingivitis and plaque. The study was a double-blind, randomized, parallel-controlled clinical trail with a total of 100 subjects who were divided into two groups, experimental group and control group. The subjects in experimental group used anti-gingivitis IgY toothpaste to brush twice daily for 3 minutes, and the subjects in control group used none anti-gingivitis IgY toothpaste. The examiner recorded GI, PI and BOP index of all subjects at the baseline, 6-weeks and 12-weeks. SPSS21.0 software package was used for statistical analysis. Twelve weeks later, there were significant differences in GI and BOP between the two groups. Yet no significant difference was found in PI. Anti-gingivitis IgY toothpaste is effective in control of gingivitis.

  1. Cellular composition of long-standing gingivitis and periodontitis lesions.

    Science.gov (United States)

    Thorbert-Mros, S; Larsson, L; Berglundh, T

    2015-08-01

    Insufficient information on the cellular composition of long-standing gingivitis lesions without signs of attachment loss makes an understanding of differences in cellular composition between "destructive" and "nondestructive" periodontal lesions difficult. The aim of the current study was to analyze differences in cell characteristics between lesions representing long-standing gingivitis and severe periodontitis. Two groups of patients were recruited. One group consisted of 36 patients, 33-67 years of age, with severe generalized periodontitis (periodontitis group). The second group consisted of 28 patients, 41-70 years of age, with overt signs of gingival inflammation but no attachment loss (gingivitis group). From each patient a gingival biopsy was obtained from one selected diseased site and prepared for immunohistochemical analysis. Periodontitis lesions were twice as large and contained significantly larger proportions, numbers and densities of cells positive for CD138 (plasma cells) and CD68 (macrophages) than did gingivitis lesions. The proportion of B cells that expressed the additional CD5 marker (B-1a cells) was significantly larger in periodontitis lesions than in gingivitis lesions. The densities of T cells and B cells did not differ between periodontitis lesions and gingivitis lesions. T cells were not the dominating cell type in gingivitis lesions, as B cells together with their subset plasma cells comprised a larger number and proportion than T cells. Periodontitis lesions at teeth with advanced attachment and bone loss exhibit quantitative and qualitative differences in relation to gingivitis lesions at teeth with no attachment and bone loss. It is suggested that the large number and high density of plasma cells are the hallmarks of advanced periodontitis lesions and the most conspicuous difference in relation to long-standing gingivitis lesions. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  2. Vertical Strip Gingival Graft: A New Technique for Gingival Augmentation A pilot study

    Directory of Open Access Journals (Sweden)

    AA. Khoshkhoonejad

    2004-06-01

    Full Text Available Statement of Problem: Although no minimum width of attached gingiva has been established as a standard for gingival health; gingival augmentation has been carried out because of many reasons. There are numerous methods for widening keratinized attached gingiva.Purpose: This study is to present "Vertical Strip Gingival Graft Technique" as an attempt to improve methods of gingival augmentation.Materials and Methods: In a before-after clinical trial 12 systematically healthy patients with no attached gingiva more than 0.5mm in at least 3 adjacent teeth were entered the study. After recipient bed preparation and harvesting free gingival graft (FGG, the graft was divided in two pieces and each part was fixed in one end of the bed. In this method an area with mean width of 6mm of recipient area, between two grafts, was remained uncovered. In order to determine the efficiency of this technique to augment attachedgingiva the distance between stent to mucogingival line (MGL and widths of attached gingival were used as indicator parameters. Clinical Parameters were measured using Wilcoxon sign rank test before surgery, 6 and 12 weeks after operation.Results: The mean value of stent to MGL in the middle part (between FGGs at the baseline, 6 and 12 weeks after operation were: 7.82±2.61mm, 11.53±1.4mm, 11.23±1.1mm respectively. The mean width of attached gingiva in those sites at the same intervals was asfollows: 0.3±0.2mm, 3.72±1.31mm, and 3.41±1.06mm. Results showed significant increase in the width of attached gingiva (P<0.01. The mean distance of stent to MGL between baseline and 6 week's data; and baseline and 12 week's also showed significant changes(P=0.001.Conclusion: With respect to the limitation of this study, by application of "vertical strip gingival graft technique" wider recipient site with less donor tissue can gain keratinizedcoverage. And as a result of producing smaller wound in the donor site (palate, patients would have less post

  3. Image analysis of normal exfoliated gingival cells

    Directory of Open Access Journals (Sweden)

    Anuradha A

    2007-01-01

    Full Text Available Objective: The present study was undertaken to evaluate the nuclear diameter (ND, cell diameter (CD and nuclear-cytoplasmic ratio (N:C and their variation with age and sex in normal gingival smears. Study Design: Gingival smears were collected from 320 apparently healthy individuals. After fixation in 95% alcohol, the smears were stained using standard papanicolaou laboratory procedure. The cell and nuclear diameters were measured using image analysis software (KS lite 2.0. Statistical analysis of the data was done using one-way ANOVA, Students ′t′ test and Tukey-HSD procedure. Results: The results showed an increase in ND from the 1-20 group to 21-40 age group in males. Above 40 years, there was a decrease in ND. In females, the ND was high in 21-40 age group; and then from 41 years, ND gradually decreased but the difference was not significant. The CD in males and females was low in the 1-20 age group and then it gradually increased. However, the difference was not significant between the ages 20 and 60 years. After 60, there was a decrease in CD. Similar changes are also seen in the ratio N:C in both males and females. The ND, CD and N:C irrespective of the age were high in females. The difference in CD was insignificant, except in the 0-20 age group, where females had significantly more cell diameters. Irrespective of the gender, the ND, CD and N:C increased from 0-20 age group to 20-40 age group. After 40, there is a steady decrease in ND, CD and N:C. Conclusion: Age-related and sex-related alterations are observed in gingival smears.

  4. Periosteoplasty for covering gingival recessions: Clinical results

    Directory of Open Access Journals (Sweden)

    Sascha Virnik

    2009-04-01

    Full Text Available Sascha Virnik1, Friedrich Michael Chiari1, Alexander Gaggl21Department of Oral and Maxillofacial Surgery, Central Hospital/LKH, Klagenfurt, Austria; 2Centre of Maxillofacial Surgery, “Pyramide am See” Clinic, Zurich, SwitzerlandAbstract: This is a case series in which a new technique for the surgical treatment of periodontal recessions is presented along with the results of the first clinical trial. A new technique of periodontal flap surgery was performed on 30 patients with severe periodontal recessions of the upper or lower front teeth. Root and soft tissue scaling was carried out with an open approach, then the periosteum was incised and mobilized at the apical part of the mucoperiosteum flap to cover the defect before the mucoperiosteum was reattached and fixed by sutures. Sulcus bleeding, periodontal probing depths, attachment loss and the length of the attached gingiva of the affected teeth were recorded preoperatively and at 3, 6, and 12 months postoperatively. Every clinical parameter was improved by surgery. No sulcus bleeding was observed at any time during the postoperative follow-up. A mean reattachment of 5.5 mm was noticed 12 months postoperatively at a mean probing depth of 0.3 mm. The mean height of the attached gingiva was 0 mm before surgery, 2.3 mm at three and six months postoperatively, and 2.2 mm at 12 months. The periosteum eversion technique is suitable for the treatment of gingival recessions resulting in good gingival function and a clear improvement in aesthetics.Keywords: periosteoplasty, periodontal surgery, gingival recession

  5. Development of labial gingival recessions in orthodontically treated patients

    NARCIS (Netherlands)

    Renkema, A.M.; Fudalej, P.S.; Kiekens, R.M.A.; Katsaros, C.

    2013-01-01

    INTRODUCTION: Our aim was to assess the prevalence of gingival recessions in patients before, immediately after, and 2 and 5 years after orthodontic treatment. METHODS: Labial gingival recessions in all teeth were scored (yes or no) by 2 raters on initial, end-of-treatment, and posttreatment (2 and

  6. Development of labial gingival recessions in orthodontically treated patients

    NARCIS (Netherlands)

    Renkema, Anne Marie; Fudalej, Piotr S.; Renkema, Alianne; Kiekens, Rosemie; Katsaros, Christos

    Introduction: Our aim was to assess the prevalence of gingival recessions in patients before, immediately after, and 2 and 5 years after orthodontic treatment. Methods: Labial gingival recessions in all teeth were scored (yes or no) by 2 raters on initial, end-of-treatment, and posttreatment (2 and

  7. Gingival biotype revisited-novel classification and assessment tool.

    Science.gov (United States)

    Fischer, Kai R; Künzlberger, Andreas; Donos, Nikolaos; Fickl, Stefan; Friedmann, Anton

    2017-05-27

    To evaluate the relationship between gingival biotypes and gingival thickness based on probe transparency through the gingival margin and to assess the sensitivity of a novel classification method. Sixty adult Caucasian subjects were stratified by their gingival biotype (GB) as defined by the transparency of a prototype double-ended periodontal probe through the buccal gingival margin into "thin" (30 subjects), "moderate" (15 subjects), and "thick" (15 subjects) GB. Three additional parameters were also assessed: gingival thickness (GT), probing depth (PD), and gingival width (GW). Median GT was 0.43 mm (P 25% 0.32; P 75% 0.58) for thin, 0.74 mm (P 25% 0.58; P 75% 0.81) for moderate, and 0.83 mm (P 25% 0.74; P 75% 0.95) for thick GB, respectively. GT was statistically significant different for thin versus moderate and thin versus thick, respectively (Kruskal-Wallis test, p biotypes based on a modified periodontal probe might be advantageous. In addition, the presence of a thick gingiva is associated with a wide band of keratinized tissue. This clinical setting might to be useful to identify high-risk patients with a very thin biotype and, consequently, higher risk for gingival recession after dental treatments.

  8. Study of oral and gingival microbial flora in institutionalized mentally ...

    African Journals Online (AJOL)

    The prevalence and severity of dental caries‚gingivitis and periodontitis is high in patients with mental retardation. This shift to a diseased state may lead to the experience of a high mortality from septicemia‚ sepsis‚ pneumonia and endocarditis.Our purpose was to study oral and gingival microbial flora in institutionalized ...

  9. Prevalence of gingivitis among school attendees in Qazvin, Iran ...

    African Journals Online (AJOL)

    Objective: The purpose of this study was to determine the gingival status in six to nine years old (6-9 years). Methods: A Total (n= 792) patients comprised 396 girls and 396 boys between 6-9 years were selected from school in Qazvin. Names, ages, sex, addresses and gingival status of each patient were recorded in ...

  10. study of oral and gingival microbial flora in institutionalized mentally

    African Journals Online (AJOL)

    boaz

    orodental hygienic condition and prevalence of dental caries, gingivitis and periodontal infection in mentally retarded people (7&8). Different studies have been conducted to investigate their microbial flora of gingival and dental plaques and its difference from that of healthy people along with its relationship with respiratory.

  11. Gingival Recession in a Child‑Patient; Easily Missed Etiologies ...

    African Journals Online (AJOL)

    periodontal diseases. European J Gen Dent 2012;1:2‑5. 15. Pini‑Prato GP, Cozzani G, Magnani C, Baccetti T. Healing of gingival recession following orthodontic treatment: A 30‑year case report. Int J Periodontics Restorative Dent 2012;32:23‑7. 16. Pradeep AR, Sharma DC. Gingival recession and pathologic migration due ...

  12. Hereditary gingival fibromatosis: report of family case series ...

    African Journals Online (AJOL)

    Hereditary gingival hyperplasia (HGF) is a rare condition characterised by hyperplastic, dense fibrous connective tissue with acanthotic gingival epithelium. A family presented at the School of Dental Sciences, University of Nairobi with a complaint that some of the children developed swollen gums very early in life and that ...

  13. Periodontal and gingival changes amongst pregnant women in ...

    African Journals Online (AJOL)

    Result: There were a higher number of sextants with gingival bleeding and shallow pockets among the pregnant women in the 2nd and 3rd trimesters of pregnancy compared to that of the non-pregnant women. The number of sextants with gingival bleeding and shallow pocket however reduced post partum. Thus, in the ...

  14. Gingival Recession in a Child‑Patient; Easily Missed Etiologies ...

    African Journals Online (AJOL)

    frenal attachment is more important in gingival recession in the child‑patient. A healthy child‑patient with impeccable oral hygiene presented with localized gingival recession without plaque‑induced inflammation which led to the exploration of other possible etiologies. Multiple factors appeared to be acting in consonance ...

  15. Gingivitis, Psychological Factors and Quality of Life in Children.

    Science.gov (United States)

    da Silva, Priscila de Lima; Barbosa, Taís de Souza; Amato, Juliana Neide; Montes, Ana Bheatriz Marangoni; Gavião, Maria Beatriz Duarte

    2015-01-01

    To evaluate the associations between gingivitis, emotional status and quality of life in children. Sixty-four Brazilian students (11 to 12 years old) were examined for clinical and self-reported gingivitis. The participants were divided into two groups: those with gingivitis (n = 21) and controls (n = 43). Quality of life, anxiety and depression were measured using self-administered questionnaires. Saliva was collected 30 min after waking and at bedtime to measure the diurnal decline in salivary cortisol. The results were analysed using bivariate and multivariate analyses. There were significantly more female participants in the control group. Approximately 90% of the children with gingivitis had good oral hygiene and 10.5% had satisfactory oral hygiene. There was a significant positive correlation between anxiety and depression in both clinical groups. Anxiety was negatively correlated with quality of life in the control group. Depression was negatively correlated with quality of life and cortisol concentrations in the group with gingivitis, and with quality of life in the control group. Children with gingivitis were more likely to be older and males. Older children are more likely to experience gingival bleeding. The presence of gingivitis in children may be associated with worse psychological well-being, possibly compromising the quality of life.

  16. Gingival Tissue Color Related With Facial Skin and Acrylic Resin ...

    African Journals Online (AJOL)

    Research into the degree of epithelial vascularisation, keratinisation and melanin pigmentation of the various zones in the mouth in this environment is required which may explain the reason for the dark colour observed in the attached gingival. Key Word: Gingival tissue colour, denture, skin, acrylic resin, Nigerians ...

  17. Amlodipine-induced gingival hyperplasia in chronic renal failure: a ...

    African Journals Online (AJOL)

    Amlodipine is a dihydropyridine calcium channel blocker that is used in the management of both hypertension and angina. Amlodipine induced side effects are headache, dizziness, edema, flushing, palpitations, and rarely gingival hyperplasia. The exact reason of amlodipine-induced gingival hyperplasia is not known.

  18. In vitro assessment of cytotoxicity of giomer on human gingival ...

    African Journals Online (AJOL)

    STORAGESEVER

    2009-10-19

    Oct 19, 2009 ... 4Department of Adult Dental Care, School of Clinical Dentistry, University of Sheffield, Sheffield, UK. Accepted 15 May, 2009 ... gingival margin apical to the cemento-enamel junction. (Deliperi et al., 2006). In a study, gingival ... of cervical structure, dental hypersensitivity and root caries (Seichter, 1987).

  19. Plasma Cell Gingivitis Associated With Inflammatory Chelitis: A ...

    African Journals Online (AJOL)

    Background: Plasma cell gingivitis (PGC) is a rare disease of gingival tissues which is difficult to treat. It has a higher rate of reoccurrence and needs a detailed and careful analysis of etiology. Further, its association with chelitis is rare, only few cases have been reported and the condition with this presentation poses a ...

  20. A Case of Gingival Myiasis Caused by Wohlfahrtia magnifica

    Directory of Open Access Journals (Sweden)

    T Mohammadzadeh

    2008-08-01

    Full Text Available A gingival myiasis in a four years old mental retarded boy with anorexia and weight loss is presented from southern part of Iran. Entomological studies on larvae showed the larvae as Wohlfartia magnifica which is a rare causative agent of gingival myiasis.

  1. Spontaneous gingivitis related to hair penetration in rats.

    Science.gov (United States)

    Goto, Aya; Sonoda, Jiro; Seki, Yuki; Taketa, Yoshikazu; Ohta, Etsuko; Nakano, Kyoko; Inomata, Akira; Hayakawa, Kazuhiro; Aoki, Toyohiko; Tsukidate, Kazuo; Hosokawa, Satoru

    2012-09-01

    Maxillary gingivae from male and female Crl:CD(SD) rats at 12, 16, 21, and 34 weeks of age were examined histologically. The incidence of gingivitis was approximately 40%, with no age or sex predilection, and was most frequent between the first and second molar. Lesions were characterized by acute focal neutrophilic infiltration into the gingival mucosa, occasionally with inflammatory exudate. In severe cases, inflammation extended to the periodontal ligament with abscess formation, and adjacent alveolar bone destruction/resorption. The most characteristic finding was the presence of hair shafts associated with the lesion, which was observed in approximately 80% of the rats with gingivitis. These findings suggest that molar gingivitis occurs in rats from an early age and persists thereafter, and that the main cause of gingivitis in rats is hair penetration into the gingiva. It would be prudent to keep these background lesions in mind as potential modifiers in toxicity studies.

  2. Clinical efficacy of turmeric use in gingivitis: A comprehensive review.

    Science.gov (United States)

    Stoyell, Karissa A; Mappus, Jennifer L; Gandhi, Mona A

    2016-11-01

    Gingivitis affects an estimated 80% of the population, and is characterized as the world's most predominant inflammatory periodontal disease. Without intervention, gingivitis can advance to alveolar bone loss. Therefore, the primary goal in patients suffering with gingivitis is to control plaque buildup and soft tissue inflammation. Current guidelines consider chlorhexidine as the gold standard in the prevention and treatment of gingivitis. However, negative side effects of chlorhexidine, including oral mucosal erosion, discoloration of teeth, and bitter taste, provide an opportunity for alternative medications. Turmeric, a commonly used herb, possesses anti-inflammatory, antioxidant, antibacterial, antiviral, and antifungal properties. By virtue of these properties, multiple controlled trials have been performed to investigate the efficacy of turmeric in gingivitis. The aim of this comprehensive review is to summarize and evaluate the evidence on the efficacy of turmeric as compared to chlorhexidine in the prevention and treatment of gingivitis. PubMed, MedLine (Web of Science), and EBSCO (academic search complete) were utilized as primary literature search tools. The following search strategy was used: ((turmeric OR curcumin OR curcuma) AND (gingivitis OR "gum inflammation")). Five reviewed studies show that both turmeric and chlorhexidine significantly decrease plaque index (PI) and gingival index (GI), and can therefore be used in the prevention and treatment of gingivitis. Both chlorhexidine and turmeric can be used as an adjunct to mechanical means in preventing and treating gingivitis. However, trials longer than 21 days with a greater number of patients are necessary to further evaluate the comparison between turmeric and chlorhexidine. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Gingival Pigmentation Affected by Smoking among Different Age Groups: A Quantitative Analysis of Gingival Pigmentation Using Clinical Oral Photographs.

    Science.gov (United States)

    Kato, Tomotaka; Mizutani, Shinsuke; Takiuchi, Hiroya; Sugiyama, Seiichi; Hanioka, Takashi; Naito, Toru

    2017-08-04

    The presence of any age-related differences in gingival pigmentation associated with smoking, particularly in a young population, remains to be fully investigated. The purpose of this study was to determine the age-related differences in smoking gingival pigmentation. Gingival pigmentation was analyzed using the gingival melanosis record (GMR) and Hedin's classification with frontal oral photographs taken at 16 dental offices in Japan. Participants were categorized into 10-year age groups, and their baseline photographs were compared. In addition, to evaluate the effect of smoking cessation on gingival pigmentation, subjects were divided into a former smoker group (stopped smoking) and current smoker group. A total of 259 patients 19 to 79 years of age were analyzed. People in their 30s showed the most widespread gingival pigmentation. In addition, subjects in their 20s showed a weak effect of smoking cessation on gingival pigmentation. These findings suggested that the gingival pigmentation induced by smoking was more remarkable in young people than in middle-aged people. This information may be useful for anti-smoking education, especially among young populations with a high affinity for smoking.

  4. Effect of Periodontal Surgery on Osteoprotegerin Levels in Gingival Crevicular Fluid, Saliva, and Gingival Tissues of Chronic Periodontitis Patients

    Directory of Open Access Journals (Sweden)

    Sandy H. S. Hassan

    2015-01-01

    Full Text Available Objectives. This study was undertaken to investigate the OPG profiles in gingival crevicular fluid (GCF, saliva, and gingival tissues of chronic periodontitis (CP patients in response to open flap debridement (OFD. Subjects and Methods. The study included 30 subjects divided into 2 groups: 20 CP patients and 10 periodontally healthy subjects. Plaque index, gingival index, pocket depth, and clinical attachment level measurements were recorded for all subjects. GCF, salivary, and gingival samples were collected from all 30 subjects at baseline and 3 and 6 month after OFD from the 20 CP patients. GCF and salivary OPG levels were assessed by ELISA assay, while OPG expression in gingival tissues was examined by immunohistochemistry. Results. GCF, salivary and gingival OPG profiles were significantly higher in control subjects compared to CP patients at baseline (P<0.001. Within CP group, OPG levels in GCF, saliva, and gingival samples showed a significant increase at 3 and 6 months after OFD (P<0.001 compared to baseline. Although OPG values increased significantly in gingival samples and insignificantly in saliva after 3 months compared to 6 months, yet GCF levels were significantly decreased. Conclusions. OPG might be considered as a diagnostic and prognostic biomarker of periodontal bone destruction. This trial is registered with NCT02160613.

  5. The effectiveness of dentifrices without and with sodium lauryl sulfate on plaque, gingivitis and gingival abrasion : a randomized clinical trial

    NARCIS (Netherlands)

    Sälzer, S.; Rosema, N.A.M.; Martin, E.C.J.; Slot, D.E.; Timmer, C.J.; Dörfer, C.E.; van der Weijden, G.A.

    2016-01-01

    Objectives The aim of this study was to compare the efficacy of a dentifrice without sodium lauryl sulfate (SLS) to a dentifrice with SLS in young adults aged 18–34 years on gingivitis. Material and methods One hundred twenty participants (non-dental students) with a moderate gingival inflammation

  6. A study on gingival component of smile

    Directory of Open Access Journals (Sweden)

    Goutam Chakroborty

    2015-01-01

    Full Text Available Background: Esthetic enhancement of smile requires prior quantification of gingival component of smile. Hence, a study has been designed on randomly selected volunteers′ and posed frontal smiling photographs were taken and analyzed through computer-aided ImageJ software. Aim: To determine the role of gingival component in designing a smile. Settings and Design: Present observational study includes one frontal photograph from each of 212 subjects who were attending the Department of Periodontics (examined during the study period and then divided into three age groups (18-30, 31-40, and 41-50 years. Materials and Methods: Standardized frontal photographs with posed smile from 212 volunteers irrespective of age and sex were taken and the images were analyzed in computer by using ImageJ software. Statistical analysis used: Mean and standard deviation of intercommissural width (ICW, interlabial gap (ILG, and smile index (SI during posed smiling were calculated for different sex. Comparison between male and female group were done by Mann-Whitney U test, and P-values were calculated for ICW, ILG, and SI. Spearman′s rank correlation coefficients (rho were calculated for SI and different components of central zone of smile. Results: Male group as compared to female group exhibited greater ICW and ILG, and there was existence of fair to good correlation between lip dynamics and different factors of smile. Conclusion: Present study indicates that different factors of central zone of smile havefair to good correlation with lip dynamics assessed by SI.

  7. Foreign body gingivitis: An iatrogenic disease

    Energy Technology Data Exchange (ETDEWEB)

    Daley, T.D.; Wysocki, G.P. (Univ. of Western Ontario, London (Canada))

    1990-06-01

    Gingival biopsy specimens from eight patients exhibiting a localized, erythematous, or mixed erythematous/leukoplakic gingivitis that was refractory to conventional periodontal therapy were examined histologically and by energy-dispersive X-ray microanalysis. Histologic examination revealed variable numbers of small, usually subtle, sometimes equivocal, and occasionally obvious foci of granulomatous inflammation. Special stains for fungi and acid-fast bacilli were consistently negative. In all cases, the granulomatous foci contained particles of foreign material that were often inconspicuous and easily overlooked during routine histologic examination. Energy-dispersive X-ray microanalysis of these foreign particles disclosed Ca, Al, Si, Ti, and P in most lesions. However, other elements such as Zr, V, Ag, and Ni were found only in specific biopsy specimens. By comparing the elemental analyses, clinical features, and history of the lesions, strong evidence for an iatrogenic source of the foreign material was found in one case, and good evidence in five cases. In the remaining two patients, the source of the foreign particles remains unresolved.

  8. [Precision and accuracy of a dental spectrophotometer in gingival color measurement of maxillary anterior gingival].

    Science.gov (United States)

    Du, Yang; Tan, Jian-guo; Chen, Li; Wang, Fang-ping; Tan, Yao; Zhou, Jian-feng

    2012-08-18

    To explore a gingival shade matching method and to evaluate the precision and accuracy of a dental spectrophotometer modified to be used in gingival color measurement. Crystaleye, a dental spectrophotometer (Olympus, Tokyo, Japan) with a custom shading cover was tested. For precision assessment, two experienced experimenters measured anterior maxillary incisors five times for each tooth. A total of 20 healthy gingival sites (attached gingiva, free gingiva and medial gingival papilla in anterior maxillary region) were measured,the Commission Internationale de I' Eclairage (CIE) color parameters (CIE L*a*b*) of which were analyzed using the supporting software. For accuracy assessment, a rectangular area of approximately 3 mm×3 mm was chosen in the attached gingival portion for spectral analysis. PR715 (SpectraScan;Photo Research Inc.,California, USA), a spectroradiometer, was utilized as standard control. Average color differences (ΔE) between the values from PR715 and Crystaleye were calculated. In precision assessment,ΔL* between the values in all the test sites and average values were from(0.28±0.16)to(0.78±0.57), with Δa*and Δb* from(0.28±0.15)to (0.87±0.65),from(0.19±0.09)to( 0.58±0.78), respectively. Average ΔE between values in all test sites and average values were from (0.62 ± 0.17) to (1.25 ± 0.98) CIELAB units, with a total average ΔE(0.90 ± 0.18). In accuracy assessment, ΔL* with control device were from(0.58±0.50)to(2.22±1.89),with Δa*and Δb* from(1.03±0.67)to(2.99±1.32),from(0.68±0.78)to(1.26±0.83), respectively. Average ΔE with the control device were from (2.44±0.82) to (3.51±1.03) CIELAB units, with a total average ΔE (2.96 ± 1.08). With appropriate modification, Crystaleye, the spectrophotometer, has demonstrated relative minor color variations that can be useful in gingival color measurement.

  9. Relationship between orthodontic treatment and gingival health: A retrospective study.

    Science.gov (United States)

    Boke, Fatma; Gazioglu, Cagri; Akkaya, Sevil; Akkaya, Murat

    2014-07-01

    The aim of this retrospective study was to evaluate the relationship between orthodontic treatment and gingival health. A total of 251 patients among whom 177 were girls and 74 were boys, recruited from the records pool of the Department of Orthodontics, Faculty of Dentistry, University of Gazi, were included in the study. Patients' treatments have been completed by postgraduate students during the period between 2006 and 2012. Patients' folders were analyzed according to their age, treatment time, and the type of orthodontic treatment. Intra-oral photographs were analyzed, and the presence or absence of visible plaque, visible inflammation, and gingival recession were recorded, and incisor inclinations analyzed on lateral cephalometric films, before and after orthodontic treatment. No statistically significant difference was found in patients treated with functional appliances before and after treatment. In patients treated with fixed orthodontic appliances, visible plaque, visible inflammation, and gingival recession showed significant increases after treatment, gingival biotype did not show any significant difference. Positive correlation was found between lower incisor position and gingival recession in patients treated with fixed appliance and extraction. And also cuspids were the teeth with the highest prevalence of gingival recession. Considering the relationship between orthodontic treatment and gingival health, cooperation among patients, orthodontists, and periodontists is important.

  10. Gingival Biotype Assessment in a Healthy Periodontium: Transgingival Probing Method.

    Science.gov (United States)

    Manjunath, R G Shiva; Rana, Anju; Sarkar, Arijit

    2015-05-01

    Gingival biotype is the thickness of the gingiva in the faciopalatal dimension. It has a significant impact on the outcome of the restorative, regenerative and implant therapy. It has been suggested that a direct co-relation exists with the susceptibility of gingival recession followed by any surgical procedure. So, the study was aimed to assess gingival biotype in different age groups of males and females using transgingival probing method. Gingival thickness (GT) was evaluated in 336 patients including males and females of different age groups. The latter was based on the transparency of the periodontal probe through the gingival margin while probing the buccal sulcus. Final data collected was then used for statistical analysis. A significant difference was found between males and females with males showing thick biotype. Out of the total samples 76.9% of males showed thick biotype compared to 13.3 % of females which was statistically significant. This was probably one of the few attempts to correlate gingival biotype with different age groups in males and females. A clear thick gingiva was found in more than two-third of the male subjects whereas majority of female subjects showed thin biotype. Also, it was seen that in females, the gingival biotype varies with age unlike in male.

  11. Gingival biotype in relation to incisors' inclination and position.

    Science.gov (United States)

    Zawawi, Khalid H; Al-Zahrani, Mohammad S

    2014-11-01

    To study the association between gingival biotypes and inclination and position of the maxillary and mandibular incisors. This cross-sectional study included 142 consecutive orthodontic patients (64 males and 78 females) who were seeking orthodontic treatment at the Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia from February 2013 to January 2014. Gingival biotype was assessed independently for the maxillary and mandibular central incisors using the transparency of periodontal probe method. Maxillary and mandibular incisors' inclination and position were measured using cephalometric analysis. The mean age was 23.56 (±2.55) years. The prevalence of thin gingival biotype was 43% for the maxillary and 52.1% for the mandibular incisors. Females were 4 times more likely to have thin gingiva for the maxillary incisors and 5 times more likely for the mandibular incisors. A significant association was found between mandibular incisor inclination and position and thin gingival biotype, while there was no association between the maxillary incisor inclination and position and gingival biotypes. Mandibular incisor proclination and protrusion is associated with thin gingival biotype while no association is found in the maxilla. The evaluation of the gingival biotype is essential during diagnosis and treatment planning for potential orthodontic patients. 

  12. [Preliminary study on gingival biotype by periodontal probing].

    Science.gov (United States)

    Le, Di; Zhang, Hao; Hu, Wen-jie; Liu, Deng-gao

    2012-02-01

    To establish a convenient, objective and applicable method to assess gingival biotype using periodontal probing. A total of 66 maxillary anterior teeth from 14 volunteers (6 males, 8 females) with healthy gingiva, aged from 20 to 30 years, were recruited in this study. The gingival biotypes were evaluated by whether or not the outline of the periodontal probe was clear inside the gingiva. Gingival thickness of the cemento-enamel junction (CEJ) in upper anterior teeth was measured by cone-beam CT (CBCT). The method of periodontal probing-assessed gingival biotype had good consistency and repeatability. The result of probing-assessed gingival biotype was consistent with that obtained by CBCT. The mean thickness of gingiva in thin, compromised and thick gingival biotype was (1.02 ± 0.20), (1.28 ± 0.25) and (1.46 ± 0.25) mm. These differences were significant for all three comparisons (P = 0.001, respectively). Periodontal probing-assessed gingival biotype is a simple, relatively objective and suitable method for clinical examination.

  13. Gingival biotype in relation to incisors’ inclination and position

    Science.gov (United States)

    Zawawi, Khalid H.; Al-Zahrani, Mohammad S.

    2014-01-01

    Objectives: To study the association between gingival biotypes and inclination and position of the maxillary and mandibular incisors. Methods: This cross-sectional study included 142 consecutive orthodontic patients (64 males and 78 females) who were seeking orthodontic treatment at the Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia from February 2013 to January 2014. Gingival biotype was assessed independently for the maxillary and mandibular central incisors using the transparency of periodontal probe method. Maxillary and mandibular incisors’ inclination and position were measured using cephalometric analysis. Results: The mean age was 23.56 (±2.55) years. The prevalence of thin gingival biotype was 43% for the maxillary and 52.1% for the mandibular incisors. Females were 4 times more likely to have thin gingiva for the maxillary incisors and 5 times more likely for the mandibular incisors. A significant association was found between mandibular incisor inclination and position and thin gingival biotype, while there was no association between the maxillary incisor inclination and position and gingival biotypes. Conclusion: Mandibular incisor proclination and protrusion is associated with thin gingival biotype while no association is found in the maxilla. The evaluation of the gingival biotype is essential during diagnosis and treatment planning for potential orthodontic patients. PMID:25399216

  14. Effect of retraction materials on gingival health: A histopathological study

    Directory of Open Access Journals (Sweden)

    Phatale Sushma

    2010-01-01

    Full Text Available Background: Gingival retraction methods are used in dentistry for impressions of subgingival crown margins, such as, mechanical, chemical, chemicomechanical, and surgical. These methods may injure the gingival sulcular epithelium. Hence, the present study is carried out to evaluate the effect of different retraction materials, such as, Expasyl, Magic Foam Cord, and impregnated retraction cord on the gingival sulcular epithelium. Materials and Methods: This study included 30 cases of bilateral premolar extraction patients with Loe and Silness gingival index zero. Retraction materials were kept in the dry, isolated labial gingival sulcus for the required time. The retraction materials were removed by rinsing with water. Retracted gingiva of 2 - 3 mm from the gingival margin along with the tooth was extracted and the decalcified sections were microscopically studied. Data analysis: Data were analyzed by applying the chi-square test. Results: This study showed better results with retraction paste as compared to the retraction cord, and there was a significant association between retraction materials and the relative degree of injury to the sulcular epithelium. Conclusion: There is a significant association between retraction materials and gingival sulcular epithelium. It can be stated that impregnated retraction cord, may be used commonly but it needs proper tissue manipulation and is technique sensitive. Newly advanced material in the form of retraction paste like Expasyl or Magic Foam Cord was found to be better than cord as assessed histologically, it respects periodontium.

  15. THERAPEUTIC DIFFICULTIES IN ACHIEVEMENT OF OPTIMAL ROOT COVERAGE AND AESTHETIC IN CLASS III GINGIVAL RECESSION.

    Directory of Open Access Journals (Sweden)

    Christina Popova

    2013-07-01

    Full Text Available The width of the attached gingiva is defined as a distance between the depth of the gingival sulcus or gingival/periodontal pocket to the mucogingival junction. Authors suggest that a minimal amount of attached gingiva is necessary to ensure the gingival health. When the buccal bone plate and gingival tissues are thin and the position of the tooth is too vestibular gingival margin often displaces apically, and gingival recession develops. In the presence of gingival recession and reduced vestibular depth oral hygiene procedures are embarrassed.The definition of class III gingival recession is marginal lack of tissue extended to/or beyond the mucogingival junction with bone and soft tissue loss interdentally or malpositioning of the tooth.Prognosis for class III and IV gingival recession is that only partial coverage can be expected after root coverage procedures - FGG (free gingival graft or connective tissue graft (CTG. Adjunctive surgical techniques would be helpful to achieve better aesthetic outcomes.

  16. Clinical Characteristics of Abutment Teeth with Gingival Discoloration.

    Science.gov (United States)

    Ristic, Ljubisa; Dakovic, Dragana; Postic, Srdjan; Lazic, Zoran; Bacevic, Miljana; Vucevic, Dragana

    2017-04-06

    The grey-bluish discoloration of gingiva (known as "amalgam tattoo") does not appear only in the presence of amalgam restorations. It may also be seen in cases of teeth restored with cast dowels and porcelain-fused-to-metal (PFM) restorations. The aim of this article was to determine the clinical characteristics of abutment teeth with gingival discoloration. This research was conducted on 25 patients referred for cast dowel and PFM restorations. These restorations were manufactured from Ni-Cr alloys. Ninety days after cementing the fixed prosthodontic restorations, the abutment teeth (n = 61) were divided into a group with gingival discoloration (GD) (n = 25) and without gingival discoloration (NGD) (n = 36). The control group (CG) comprised the contralateral teeth (n = 61). Plaque index, gingival index, clinical attachment level, and probing depth were assessed before fabrication and also 90 days after cementation of the PFM restorations. The gingival index, clinical attachment level, and probing depths of the abutment teeth that had GD were statistically higher before restoration, in comparison with the abutment teeth in the NGD and control groups. Ninety days after cementation, the abutment teeth with GD had significantly lower gingival indexes and probing depths, compared to the abutment teeth in the NGD group. Both abutment teeth groups (GD and NGD) had significantly higher values of clinical attachment levels when compared to the control group. There were no statistically significant differences in plaque index values between the study groups. The results of this study indicated that impairment of periodontal status of abutment teeth seemed to be related to the presence of gingival discolorations. Therefore, fabrication of fixed prosthodontic restorations requires careful planning and abutment teeth preparation to minimize the occurrence of gingival discolorations. With careful preparation of abutment teeth for cast dowels and crown restorations it may be

  17. Microcirculation alterations in experimentally induced gingivitis in dogs.

    Science.gov (United States)

    Matsuo, Masato; Okudera, Toshimitsu; Takahashi, Shun-Suke; Wada-Takahashi, Satoko; Maeda, Shingo; Iimura, Akira

    2017-01-01

    The present study aimed to morphologically examine the gingival microvascular network using a microvascular resin cast (MRC) technique, and to investigate how inflammatory disease functionally affects gingival microcirculation using laser Doppler flowmetry (LDF). We used four beagle dogs with healthy periodontal tissue as experimental animals. To cause periodontal inflammation, dental floss was placed around the cervical neck portions of the right premolars. The unmanipulated left premolars served as controls, and received plaque control every 7 days. After 90 days, gingivitis was induced in the experimental side, while the control side maintained healthy gingiva. To perform morphological examinations, we used an MRC method involving the injection of low-viscosity synthetic resin into the blood vessels, leading to peripheral soft-tissue dissolution and permitting observation of the bone, teeth, and vascular cast. Gingival blood flow was estimated using an LDF meter. The control gingival vasculature showed hairpin-loop-like networks along the tooth surface. The blood vessels had diameters of 20-40 μm and were regularly arranged around the cervical portion. On the other hand, the vasculature in the experimental group was twisted and gathered into spiral forms, with blood vessels that had uneven surfaces and smaller diameters of 8-10 μm. LDF revealed reduced gingival blood flow in the group with experimentally induced gingivitis compared to controls. The actual measurements of gingival blood flow by LDF were in agreement with the alterations that would be expected based on the gingivitis-induced morphological alterations observed with the MRC technique.

  18. Diarrea crónica refractaria y malabsorción secundaria a hipogammaglobulinemia común variable, infestación crónica por giardia lamblia y gastrectomía total por adenocarcinoma gástrico: un manejo nutricional complejo Chonic diarrhea and malabsorption due to common variable immunodeficiency, gastrectomy and giardiasis infection: a difficult nutritional management

    OpenAIRE

    M. E. Domínguez-López; I. González-Molero; C. P. Ramírez-Plaza; F. Soriguer; G. Olveira

    2011-01-01

    El adenocarcinoma gástrico es una de las causas más frecuentes de mortalidad en el mundo, siendo la cirugía el único tratamiento potencialmente curativo, aunque los efectos adversos digestivos y nutricionales son frecuentes y abundantes. La hipogammaglobulinemia variable común es causa de frecuentes manifestaciones digestivas, derivándose las más importantes en diarrea crónica causada por giardiasis, hiperplasia nodular linfoide o atrofia vellosa, siendo frecuente la malabsorción y la desnutr...

  19. A stab-and-roll biopsy technique to maintain gingival epithelium for desquamative gingivitis.

    Science.gov (United States)

    Endo, Hiroyasu; Rees, Terry D; Allen, Edward P; Kuyama, Kayo; Aoki, Shinichiro; Yamamoto, Hirotsugu; Ito, Takanori

    2014-06-01

    Desquamative gingivitis (DG) is a clinical manifestation common to several diseases. It is known that most cases of DG are caused by mucous membrane pemphigoid (MMP), oral lichen planus (OLP), or pemphigus vulgaris (PV). Early recognition and treatment of these diseases can improve the prognosis, but diagnostic delays are common in patients with DG because obtaining a diagnostic biopsy is technically challenging. A biopsy technique designed to maintain the gingival epithelium for patients with DG was developed. The usefulness of this technique is discussed. This study is based on a retrospective review of 27 DG cases. A stab-and-roll technique was used to obtain gingival tissue. This technique is designed to reduce lateral forces on the epithelium during the procedure and to thereby prevent the inadvertent removal of the epithelium from the biopsy specimen. A total of 52 biopsies comprising 27 for hematoxylin and eosin (H&E)-stained samples and 25 for direct immunofluorescence (DIF) testing were reviewed. Fifty-one of the 52 biopsies (98.1%) maintained the epithelium. Only one biopsy (1.9%) showed that the epithelium was totally absent. Therefore, H&E and DIF features of 51 biopsies were analyzed. Definitive diagnoses of the diseases causing DG included MMP (13 cases), PV (eight cases), and OLP (six cases). A diagnostic biopsy was obtained from the gingiva of patients with DG using the stab-and-roll technique. The gingival epithelium was well maintained, and the relationship with the underlying connective tissue was diagnostic. In the future, this stab-and-roll biopsy technique may facilitate early diagnosis and treatment of diseases causing DG.

  20. Panacea to lost gingival tissue architecture and spacing: Silicone gingival prosthesis.

    Science.gov (United States)

    Tomar, Brajendra S; Chandu, G S; Singh, Shubhra; Goutam, Manish

    2016-01-01

    The positive psychological effects of improving patients' smile often contribute to an improved self-image and enhanced self-esteem. Periodontal disease may lead to tooth and tissue loss that can result in esthetic problems. Combined periodontal/prosthodontic treatment for patients with advanced disease is well documented. This case report illustrates a method of treatment for an advanced tissue loss in an esthetic area using a removable silicone gingival prosthesis/mask.

  1. Panacea to lost gingival tissue architecture and spacing: Silicone gingival prosthesis

    Directory of Open Access Journals (Sweden)

    Brajendra S Tomar

    2016-01-01

    Full Text Available The positive psychological effects of improving patients' smile often contribute to an improved self-image and enhanced self-esteem. Periodontal disease may lead to tooth and tissue loss that can result in esthetic problems. Combined periodontal/prosthodontic treatment for patients with advanced disease is well documented. This case report illustrates a method of treatment for an advanced tissue loss in an esthetic area using a removable silicone gingival prosthesis/mask.

  2. Gingival enlargement unveiling sarcoidosis: Report of a rare case

    Directory of Open Access Journals (Sweden)

    Sabeeha Abbas Kadiwala

    2013-01-01

    Full Text Available Sarcoidosis is classified as an acquired systemic granulomatous disease. Because of the fact that sarcoidosis affects multiple tissues and organs, it is characterized by many potential signs and symptoms, as well as by the presence of non-caseating granulomas in the organs involved. Although oral sarcoidosis is relatively rare, it may however, present in the oral cavity. This report presents a rare case of sarcoidosis with the initial presenting symptom as severe generalized gingival enlargement. The gingival enlargement was treated by gingivectomy. After histopathological examination of gingival biopsy and certain special investigations, a diagnosis of sarcoidosis was made.

  3. Management of excessive gingival display: Lip repositioning technique

    Directory of Open Access Journals (Sweden)

    Upasana Sthapak

    2015-01-01

    Full Text Available The lips form the frame of a smile and define the esthetic zone. Excessive gingival display during smile is often referred to as "gummy smile". A successful management of excessive gingival display with lip repositioning procedure has shown excellent results. The procedure involves removing a strip of partial thickness mucosa from maxillary vestibule, then suturing it back to the lip mucosa at the level of mucogingival junction. This technique results in restricted muscle pull and a narrow vestibule, thereby reducing the gingival display. In this case gummy smile was treated by modification of Rubinstein and Kostianovsky′s surgical lip repositioning technique which resulted in a harmonious smile.

  4. Coverage of gingival recession using tunnel connective tissue graft technique

    Science.gov (United States)

    Khuller, Nitin

    2009-01-01

    The recession of gingiva is increasingly becoming a more prominent condition in the oral health of many patients and should be treated at its earliest detection. The multi-factorial etiology, decision modality, and current trends followed in treatment of gingival recession are discussed in this presentation. The correction of class I and II gingival recessions are presented as a means of minimizing surgical trauma and achieving predictable aesthetic results. In this case report, I present an alternative technique in treating gingival recession- the tunnel connective tissue graft. PMID:20407659

  5. Coverage of gingival recession using tunnel connective tissue graft technique

    Directory of Open Access Journals (Sweden)

    Khuller Nitin

    2009-01-01

    Full Text Available The recession of gingiva is increasingly becoming a more prominent condition in the oral health of many patients and should be treated at its earliest detection. The multi-factorial etiology, decision modality, and current trends followed in treatment of gingival recession are discussed in this presentation. The correction of class I and II gingival recessions are presented as a means of minimizing surgical trauma and achieving predictable aesthetic results. In this case report, I present an alternative technique in treating gingival recession- the tunnel connective tissue graft.

  6. Management of gingival hyperpigmentation by semiconductor diode laser.

    Science.gov (United States)

    Gupta, Geeti

    2011-09-01

    Gingival hyperpigmentation is caused by excessive deposition of melanin in the basal and suprabasal cell layers of the epithelium. Although melanin pigmentation of the gingiva is completely benign, cosmetic concerns are common, particularly in patients having a very high smile line (gummy smile). Various depigmentation techniques have been employed, such as scalpel surgery, gingivectomy, gingivectomy with free gingival autografting, cryosurgery, electrosurgery, chemical agents such as 90% phenol and 95% alcohol, abrasion with diamond burs, Nd:YAG laser, semiconductor diode laser, and CO(2) laser. The present case report describes simple and effective depigmentation technique using semiconductor diode laser surgery - for gingival depigmentation, which have produced good results with patient satisfaction.

  7. Free gingival graft in the treatment of class III gingival recession

    Directory of Open Access Journals (Sweden)

    Remya V

    2008-01-01

    Full Text Available Aim: The purpose of this study was to assess the success and predictability of root coverage and esthetics obtained with free gingival grafts (FGGs in the treatment of early class III gingival recessions for a period of 12 months. Materials and Methods: Ten patients contributed to 12 sites, each with early class III recession with interdental bone loss £4 mm from cemento enamel junction(CEJ. Clinical parameters recorded at baseline and at 1, 6, and 12 months were probing depth (PD, recession depth (RD, recession width (RW, and clinical attachment level (CAL. Results: Reduction of recession resulted in a significant gain in CAL and PD at the end of 12 months. A statistically significant mean root coverage of 41.25 ± 21.07% was obtained at the end of 12 months. A statistically significant improvement in Visual Analog Scale score was seen after a 12-month follow-up period. Conclusion: In a south Indian population, early class III gingival recessions treated with FGG procedures resulted in 40-50% root coverage with fairly acceptable esthetics.

  8. Hiperplasia adrenal congênita: dosagem da 17-hidroxiprogesterona basal para seleção e casos para realização do teste de estímulo com ACTH sintético Congenital adrenal hyperplasia: measurement of basal 17-hydroxyprogesterone as a screening test to select patients for the synthetic ACTH provocative test

    Directory of Open Access Journals (Sweden)

    Lúcia Helena Coelho Nóbrega

    2004-05-01

    Full Text Available OBJETIVOS: avaliar se os níveis de 17-hidroxiprogesterona podem predizer o resultado do teste de estímulo como diagnóstico de hiperplasia adrenal congênita, forma tardia. MÉTODOS: foram incluídas no estudo e avaliadas retrospectivamente 122 pacientes com suspeita clínica de hiperplasia adrenal congênita forma tardia. Essa suspeita clínica incluía sinais e/ou sintomas de hiperandrogenismo (hirsutismo, acne, pele oleosa, irregularidade menstrual, etc.. Todas as pacientes foram submetidas ao teste de estímulo da adrenal com ACTH sintético 0,25 mg (Synacthen®. Após repouso de 60 minutos as amostras foram colhidas nos tempos basal e 60 minutos após a administração de 0,25 mg de ACTH sintético para dosagem de 17-hidroxiprogesterona, sendo mantido o acesso venoso com catéter heparinizado. Foi utilizado o método de radioimunoensaio para realizar as dosagens séricas da 17-hidroxiprogesterona. A sensibilidade e a especificidade da 17-hidroxiprogesterona basal como teste de rastreamento para hiperplasia adrenal congênita foram medidas, avaliando vários pontos de corte. Curvas ROC foram feitas para analisar a performance do teste, utilizando o software Medcalc®. RESULTADOS: a análise por curva ROC mostrou um ponto de corte de 181 ng/dl acima do qual dever-se-ia realizar o teste de estímulo, bem próximo a 200 ng/dl, mais comumente aceito pela literatura. Níveis séricos da 17-hidroxiprogesterona mais altos que 200 ng/dl têm valores preditivo positivo e negativo de 75% e 100% e acurácia de 98,4% como diagnóstico de hiperplasia adrenal não-clássica. CONCLUSÕES: considerando os dados, sugerimos que pacientes com hiperandrogenismo clínico devam iniciar a investigação com 17-hidroxiprogesterona basal e, caso esta se mostre acima de 181 ng/dl, sigam a investigação com o teste de estímulo com ACTH sintético.INTRODUCTION: adrenal hyperplasia is a common genetic disorder and 95% of the cases are due to a 21-hydroxylase

  9. Congenital adrenal hyperplasia: Clinical characteristics and genotype in newborn, childhood and adolescence Hiperplasia suprarrenal congénita: Características clínicas, seguimiento y genotipo en la etapa perinatal, la niñez y la adolescencia

    Directory of Open Access Journals (Sweden)

    Titania Pasqualini

    2007-06-01

    Full Text Available Congenital adrenal hyperplasia (CAH due to 21-hydroxylase deficiency is a disorder which can adopt three clinical expressions: two classical forms -salt-wasting (SW, with residual enzymatic activity (EA La hiperplasia suprarrenal congénita por déficit de 21-hidroxilasa presenta tres formas clínicas: dos clásicas, perdedora de sal, con actividad enzimática (AE < 1% y virilizante simple, con AE 1-2% y una no clásica, con AE 10-60%. Nuestro objetivo es describir las características clínicas y el genotipo de un grupo de pacientes con hiperplasia suprarrenal congénita; este último también se determinó en todos los miembros de la familia. Se estudiaron 9 pacientes diagnosticados en la etapa perinatal y 8 durante la etapa pre y postpuberal. Se analizaron diez mutaciones en el gen CYP21A2 y se evaluó crecimiento y densidad mineral ósea. Once pacientes presentaron la forma clásica: 9 con diagnóstico perinatal y 2 diagnosticados más tardíamente, uno de ellos con agrandamiento testicular por restos adrenales. Todos los pacientes, salvo 1 con una mutación de novo R356W en un alelo, presentaron ambos alelos mutados con un genotipo que predice AE < 2%. Seis pacientes presentaron la forma no clásica, todos con signos clínicos de hiperandrogenismo salvo un familiar asintomático que se diagnosticó por el estudio molecular. Todos, a excepción de uno con un alelo aún no determinado, presentaron la mutación V281L acompañada de otra que predice AE < 2%. Durante la evolución de los pacientes de diagnóstico perinatal se observó talla baja al año con recuperación de la misma en la etapa prepuberal. La densidad mineral ósea fue normal. Podemos concluir que el diagnóstico en la etapa perinatal en pacientes con la forma clásica posibilita un mejor seguimiento y crecimiento. La genotipificación de todos los miembros de una familia permite el diagnóstico de formas asintomáticas. La presencia de mutaciones de novo y de un alelo con una

  10. Effect of periodontal surgery on osteoprotegerin levels in gingival crevicular fluid, saliva, and gingival tissues of chronic periodontitis patients.

    Science.gov (United States)

    Hassan, Sandy H S; El-Refai, Mahmoud I; Ghallab, Noha A; Kasem, Rehab Fawzy; Shaker, Olfat G

    2015-01-01

    This study was undertaken to investigate the OPG profiles in gingival crevicular fluid (GCF), saliva, and gingival tissues of chronic periodontitis (CP) patients in response to open flap debridement (OFD). The study included 30 subjects divided into 2 groups: 20 CP patients and 10 periodontally healthy subjects. Plaque index, gingival index, pocket depth, and clinical attachment level measurements were recorded for all subjects. GCF, salivary, and gingival samples were collected from all 30 subjects at baseline and 3 and 6 month after OFD from the 20 CP patients. GCF and salivary OPG levels were assessed by ELISA assay, while OPG expression in gingival tissues was examined by immunohistochemistry. GCF, salivary and gingival OPG profiles were significantly higher in control subjects compared to CP patients at baseline (P saliva, and gingival samples showed a significant increase at 3 and 6 months after OFD (P saliva after 3 months compared to 6 months, yet GCF levels were significantly decreased. OPG might be considered as a diagnostic and prognostic biomarker of periodontal bone destruction. This trial is registered with NCT02160613.

  11. Measurement of Reduced Gingival Melanosis after Smoking Cessation: A Novel Analysis of Gingival Pigmentation Using Clinical Oral Photographs

    Directory of Open Access Journals (Sweden)

    Tomotaka Kato

    2016-06-01

    Full Text Available Background: Due to moisture and the anatomical complexity of the oral mucosa, it is difficult to measure the extent of gingival melanosis in an optical manner. Therefore, we developed a new quantitative method using clinical oral photographs and compared the extent of gingival melanosis before and after smoking cessation. Methods: A new analysis method, which we named the gingival melanosis record (GMR, is a quantitative analysis method using clinical oral photographs. We obtained 659 clinical photographs from 263 patients from 16 general dental offices in Japan. Standardized measuring sites were automatically spotted on the screen, and the presence of gingival melanosis was determined at the measuring sites. We assessed the validity of the GMR with the previously reported Hedin’s classification using Spearman’s rank correlation and intraclass correlation coefficients. Results: The GMR showed a significant association with Hedin’s classification (p < 0.01, correlation coefficient = 0.94. The GMR also showed excellent reproducibility of the substantial repeated agreement intraclass correlation coefficients (ICC (1,1 and ICC (2,1, p > 0.61. The longitudinal loss of gingival melanosis was confirmed by a change in the GMR among patients who successfully achieved smoking cessation for a mean of 4.5 years. Conclusion: The GMR is an effective method to assess gingival melanosis. The loss of gingival melanosis after smoking cessation can be objectively confirmed with the use of the GMR.

  12. Severe gingival enlargement associated with aggressive periodontitis

    Directory of Open Access Journals (Sweden)

    Shyam Padmanabhan

    2013-01-01

    Full Text Available Enlargement of the gingiva can be due to various causes. Most prevalent are the inflammatory type and drug-induced type of gingival hyperplasia. However, sever enlargement associated with an aggressive type of periodontitis is an infrequent finding. Reported here is a case of a female patient aged 18 years who presented with severe enlargement of the maxillary and mandibular gingiva. Examination revealed enlargement extending up to the incisal edge of all the teeth and also an associated generalized loss of attachment with radiographic evidence of reduced bone height resembling an aggressive type of periodontitis. There were no associated systemic signs and symptoms or any family history except that there was generalized vitiligo of the skin and oral mucous membrane. The case was treated by gross electrosection of the gingiva.

  13. Prevalencia y grado de gingivitis asociada a placa dentobacteriana en niños

    Directory of Open Access Journals (Sweden)

    Miriam Lucía Rocha Navarro

    2014-01-01

    Full Text Available Introducción: Las enfermedades periodontales (EPs son comunes en niños y adolescentes, y algunas son rápidamente destructivas. El consenso internacional de Periodontología de 1999, vigente hasta hoy día, incluyó a la gingivitis como parte de las EPs. Este estudio se enfocó en la gingivitis inducida por placa dentobacteriana (PDB. Estudios previos reportan porcentajes similares de prevalencia en niños Nigerianos, Polacos y Tanzaneses de alrededor del 54.4%. Sin embargo Oh TJ y col. encontró una presencia del 70% en niños Estadounidenses. En México, hay una amplia discrepacia en su prevalencia que oscila entre el 20.6% - 91.3%. Método: Estudio observacional, transversal y descriptivo de niños que acudieron al Departamento de Odontopediatría de la Universidad de La Salle Bajío, A. C. Se revisó un total de 545 niños, y de ellos se reclutaron 350 niños con gingivitis de entre 3-14 años de edad, ambos sexos, clasificados sistémicamente como tipo I y II y sin capacidades diferentes. El protocolo de investigación fue revisado y aprobado por el Comité Ético Institucional. Los padres de los niños incluidos firmaron una Carta de Consentimiento Informado. A los niños se les aplicó un cuestionario de salud sistémica y uno de higiene dental, así como evaluación clínica, periodontal y de control de PDB. A los padres se les aplicó un cuestionario de hábitos higiénicos y preventivos. Se utilizó estadística descriptiva, X2 y correlación múltiple. Resultados: Los niños presentaron una prevalencia de 64.2%, con una mediana grado I de gingivitis, sin embargo, se observó una tendencia a incrementarse el grado de ésta, conforme el niño tenía más edad, así como un incremento en la presencia de PDB de acuerdo con el índice de O’Leary. No se observaron diferencias en el grado de gingivitis entre sexos. Conclusión: El índice gingival en los niños estudiados es grado I, que es considerado leve y éste es independiente del

  14. Generalised Leukaemic Gingival Enlargement: a Case Report

    Directory of Open Access Journals (Sweden)

    Mechery Reenesh

    2012-09-01

    Full Text Available Background: Acute myeloblastic leukaemia is a malignant bone marrow neoplasm of myeloid precursors of white blood cells. Due to its high morbidity rate, early diagnosis and appropriate medical therapy is essential. Methods: The article highlights normal blood alterations like anaemia, thrombocytopenia, leukocytosis and advanced diagnostic aids like flow cytometry, special staining as a diagnostic modality as well as for prognostic information in acute leukaemia, particularly as a tool for assigning lineage and facilitating further pathologic classification which may be helpful in influencing treatment strategies.Results: On clinical examination the case presented with features of inflammatory gingival enlargement with presence of local deposits and calculus. Routine blood examination anaemia, thrombocytopenia, leukocytosis with haemoglobin 5.6 gm% and total leukocyte count of 1,12,000 / cu mm suggestive of leukaemia. Myeloperoxidase and leukocyte nonspecific esterase (NSE special stain were used which showed presence of myeloblasts in the peripheral smear suggestive of acute myelocytic leukaemia. Flow cytometry were done which further helped in interpretation of these cells which showed to be strongly positive for CD45, CD13, CD14, and anti HLADR and moderately positive for CD4, CD34 and Anti MPO confirming to be case of AML-M4 with 57.73% gating.Conclusions: Fact that gingival alterations are sometimes the first manifestations of the disease implies that dental professionals must be sufficiently familiarized with the clinical manifestations of systemic diseases. The timely referral by the general dentist for a suspicious lesion provided an early diagnosis and early intervention reducing the patient morbidity.

  15. Expressão das citoceratinas em dermatoses infecto- parasitárias associadas à hiperplasia epidérmica Expression of the cytokeratins in infectious and parasitic skin diseases associated with epidermal hyperplasia

    Directory of Open Access Journals (Sweden)

    Maria Christina Marques Nogueira-Castañon

    2004-12-01

    Full Text Available FUNDAMENTOS: As citoceratinas(C são as proteínas estruturais mais importantes das células epiteliais e exibem a maior heterogeneidade dentre todas as proteínas dos filamentos intermediários. Seu estudo através de imunomarcação possibilita a análise estrutural do citoesqueleto em vários afecções neoplásicas e inflamatórias. OBJETIVOS: Verificar o padrão imuno-histoquímico da expressão das citoceratinas na epiderme de doenças infecto-parasitárias associadas à hiperplasia escamosa. MÉTODOS: Cortes histológicos obtidos de tecidos pré-fixados e incluidos em parafina à partir de lesões de cromomicose, paracoccidioidomicose, leishmaniose e condiloma acuminado foram marcados com os anticorpos DEK10, LL025, LL002 e AE1 pela técnica de imunoperoxidase (avidina-biotina. RESULTADOS: A análise de áreas com intensidade variável de hiperplasia epidérmica presentes nos fragmentos mostrou exclusivamente e/ou predominantemente nas quatro doenças: ausência de expressão da C10 nas áreas de hiperplasia intensa e retardo da expressão nas áreas de hiperplasia moderada e/ou ausente; padrão suprabasal de marcação para a C16 independentemente do grau de hiperplasia como também, liberação de epítopos suprabasais para os marcadores LL002 (C14 e AE1 (C10,14,16,19. CONCLUSÕES: As modificações indicam que, independentemente da natureza do agente etiológico e do grau de hiperplasia presente, ocorrem alterações na diferenciação e proliferação do ceratinócito.BACKGROUND: Cytokeratins (K are the major structural proteins of epithelial cells and they display the greatest heterogeneity of all intermediate filament proteins. The study of many isolated cytokeratins by immunomarcation enables the structural verification of the cytoskeleton in many neoplastic and inflammatory diseases. OBJECTIVE: To verify the immunohistochemical pattern of cytokeratin expression in infectious and parasitic diseases associated with squamous

  16. Láser helio-neón combinado con clorhexidina al 0,2 %.: Efectos clínicos y microbiológicos en el tratamiento de la gingivitis crónica Helium-neon laser combined with 0.2% chlorhexidine: Clinical and microbiological effects in the treatment of chronic gingivitis.

    OpenAIRE

    Tatiana Peña Ruiz; Ariel Delgado Ramos; Ariadna González Lorenzo

    2007-01-01

    La gingivitis crónica constituye una de las formas más frecuentes de enfermedad periodontal, caracterizada por la inflamación crónica de la encías, tumefacción, enrojecimiento y sangramiento. Su principal factor de riesgo lo constituye la microbiota del surco gingival, que resulta necesario, pero no suficiente para desencadenarla. Se realizó un ensayo clínico-terapéutico fase II, controlado, aleatorizado y a simple ciegas, para evaluar los efectos clínicos y microbiológicos del tratamiento co...

  17. Gingival recession--can orthodontics be a cure?

    National Research Council Canada - National Science Library

    Northway, William M

    2013-01-01

    .... With an extensive review of the literature, this case review attempts to make sense of the enigma of gingival recession and demonstrates an excellent treatment solution to concomitant orthodontic...

  18. Proteolytic Mediators in Gestational Diabetes Mellitus and Gingivitis.

    Science.gov (United States)

    Akcalı, Aliye; Gümüş, Pınar; Özçaka, Özgün; Öztürk-Ceyhan, Banu; Tervahartiala, Taina; Husu, Heidi; Heikkinen, Anna Maria; Sorsa, Timo; Buduneli, Nurcan

    2017-03-01

    This study evaluates levels of matrix metalloproteinase (MMP)-8, MMP-9, and tissue inhibitor of MP-1 (TIMP-1) in biofluids of women with gestational diabetes mellitus (GDM) and systemically healthy counterparts with different statuses of periodontal health. Seventy-one women with GDM and gingivitis (Gg), 30 women with GDM and healthy periodontium (Gh), 28 systemically and periodontally healthy women (Hh), and 37 systemically healthy women with gingivitis (Hg) were evaluated. MMP-8, MMP-9, and TIMP-1 levels were determined in gingival crevicular fluid (GCF), saliva, and serum by immunofluorometric and enzyme-linked immunosorbent assays. Full-mouth clinical periodontal parameters were recorded. GCF and serum MMP-8 concentrations, serum MMP-9 concentrations, and serum MMP-8/MMP-1 and MMP-9/MMP-1 molar ratios were significantly higher in Gg compared with Hg group (P gingivitis.

  19. Quantitative cytomorphometric analysis of exfoliated normal gingival cells

    Directory of Open Access Journals (Sweden)

    Punit Vaibhav Patel

    2011-01-01

    Conclusion: Age-and sex-related alterations were observed in gingival smears, which could be a baseline for these variables to compare identical measurements, made on pathologic smears of oral premalignant and malignant lesions.

  20. A Spectrophotometric Color Evaluation of Natural Teeth and Gingival

    DEFF Research Database (Denmark)

    Peng, Min; Hosseini, Mandana; Gotfredsen, Klaus

    2012-01-01

    positions of each tooth (incisal 1/3, body1/3, cervical 1/3 and gingival) were assessed using a spectrophotometer (SpectroShadeTM, Micro Dental, Seria No. HDL3214, MHT, S.p.A, Italy) in CIELab coordinates. Descriptive statistics of Spss17.0 was used to analyze the distribution of color coordinates. Pearson...... correlation was used to test the relationship between the coordinates and age. Independent t test was used to test the difference between gender groups. Results: All the color coordinates for teeth and gingival were in right-left symmetric distribution by the central incisors and the distribution was in same...... mode at each tooth. The body part of the central incisor had the highest L value and the cervical part of the canine had the highest a, b value. No statistical difference was found among positions regarding the gingival color. Statistical correlation was found between the gingival color...

  1. Amnion membrane for coverage of gingival recession: A novel application

    Directory of Open Access Journals (Sweden)

    Rucha Shah

    2014-01-01

    Full Text Available Introduction: Amnion allograft has been used in the field of medicine for its exceptional wound-modulating properties. However, in the field of dentistry, only a limited number of reports have explored its potential in healing of oral wounds. Materials and Methods: Amnion allograft in conjunction with coronally advanced flap has been used in the management of gingival recession. Results: A complete coverage along with excellent esthetics and an improvement in gingival biotype was observed at 6 months postoperatively. Discussion: Because of its inherent wound-modulating properties, amnion allograft may be used to enhance periodontal wound healing and enable tissue regeneration such as that in the coverage of gingival recession. Conclusion: Amnion allograft may provide an alternative to other conventional methods of treating gingival recession.

  2. Drug-induced gingival overgrowth: The nemesis of gingiva unravelled

    Directory of Open Access Journals (Sweden)

    Vipin Bharti

    2013-01-01

    Full Text Available Drug-induced gingival overgrowth or enlargement manifests as abnormal growth of the gingiva due to an adverse drug reaction (ADR in patients treated with anticonvulsants, immunosuppressants, and calcium channel blockers. As gingival enlargement develops, it affects the normal oral hygiene practice and may interfere with masticatory functions. It gradually becomes a source of pain and the condition often leads to disfiguration. Within the group of patients that develop this unwanted effect, there appears to be variability in the extent and severity of the gingival changes. It would seem pertinent to identify and explore possible risk factors and relating them with the treatment plan. This article throws light on respective drugs and their association with gingival overgrowth and approaches to treatment based on current knowledge and investigative observations.

  3. Drug-induced gingival overgrowth: The nemesis of gingiva unravelled.

    Science.gov (United States)

    Bharti, Vipin; Bansal, Chhaya

    2013-03-01

    Drug-induced gingival overgrowth or enlargement manifests as abnormal growth of the gingiva due to an adverse drug reaction (ADR) in patients treated with anticonvulsants, immunosuppressants, and calcium channel blockers. As gingival enlargement develops, it affects the normal oral hygiene practice and may interfere with masticatory functions. It gradually becomes a source of pain and the condition often leads to disfiguration. Within the group of patients that develop this unwanted effect, there appears to be variability in the extent and severity of the gingival changes. It would seem pertinent to identify and explore possible risk factors and relating them with the treatment plan. This article throws light on respective drugs and their association with gingival overgrowth and approaches to treatment based on current knowledge and investigative observations.

  4. Case report of gingivitis artefacta (Self-injurious behavior

    Directory of Open Access Journals (Sweden)

    Altaf H Chalkoo

    2016-01-01

    Full Text Available This case report discusses gingivitis artefacta, an oral presentation of self-injurious behavior (SIB, in a 26-year-old male who also presented with excoriations on the chest, abdomen and back (dermatillomania along with well-circumscribed areas of hair loss on the scalp (trichotillomania. Gingivitis artefacta is a type of periodontal disease caused by self-inflicted injuries to the gingival tissues. The injuries, most commonly, occur due to picking or scratching of the gingiva with fingernails or any foreign object. SIB is a complex disorder. The cause of his behavior appeared to be of psychological origin, and therefore, referral to the Department of Psychiatry was made. Gingivitis artefacta is rarely seen and practitioners need to be aware of such presentations in patients.

  5. Gingival and Periodontal Diseases in Children and Adolescents

    Directory of Open Access Journals (Sweden)

    Vivek Singh Chauhan

    2012-01-01

    Full Text Available Periodontal diseases are among the most frequent diseases affecting children and adolescents. These include gingivitis, localized or generalized aggressive periodontitis (a.k.a., early onset periodontitis and periodontal diseases associated with systemic disorders. The effects of periodontal diseases observed in adults have earlier inception in life period. Gingival diseases in a child may progress to jeopardize the periodontium in adulthood. Therefore, periodontal diseases must be prevented and diagnosed early in the life. This paper reviews the most common periodontal diseases affecting children: chronic gingivitis (or dental plaque-induced gingival diseases and aggressive periodontitis. In addition, systemic diseases that affect the periodontium in young children and necrotizing periodontal diseases are addressed. The prevalence, diagnostic characteristics, microbiology, host- related factors, and therapeutic management of each of these disease entities are discussed.

  6. Administração de toxina botulínica A e a orquiectomia no tratamento da hiperplasia prostática benigna do cão

    OpenAIRE

    Mostachio, Giuliano Queiroz [UNESP; Apparício, Maricy [UNESP; Motheo, Tathiana Ferguson; Alves,Aracélle Elisane; Vicente, Wilter Ricardo Russiano [UNESP

    2015-01-01

    A fisiopatologia da hiperplasia prostática benigna (HPB) não está totalmente compreendida, no entanto, a diidrotestosterona é o principal hormônio envolvido. Recentemente, o efeito da toxina botulínica A (TB-A) foi investigado, mostrando que esta induz atrofia do parênquima e redução do volume prostático. Com base nisso, este estudo teve como objetivos comparar os efeitos da administração da TB-A com a orquiectomia no tratamento da HPB, além de avaliar os efeitos da TB-A sobre a libido e qual...

  7. Reconstrucción genital integral en la Hiperplasia Suprarrenal Congénita: sensibilidad, estética y función (embarazo) Integral genital reconstruction: sensitivity, aesthetic and function (pregnancy), in the Congenital Adrenal Hyperplasia

    OpenAIRE

    A.A. Núñez Serrano; M. Núñez Laiseca; E. Elena Sorando; J.L. Arranz López; García Martínez, L.

    2010-01-01

    La Hiperplasia Suprarrenal Congénita o Síndrome Adrenogenital es un cuadro clínico poco frecuente. Las anomalías que presenta van asociadas a síndromes que a veces son muy complejos, destacando, entre otros, el seudohermafroditismo femenino y el hermafroditismo verdadero. Las mujeres que la padecen presentan como alteración más evidente un clítoris aumentado de tamaño (megaloclítoris) y otras alteraciones en los genitales externos. Ante estas pacientes es necesario realizar un diagnostico cor...

  8. Hiperplasia epitelial focal (doença de Heck) em descendente de índios brasileiros: relato de caso Focal epithelial hyperplasia (Heck's disease) in Brazilian indian descent: report of a case

    OpenAIRE

    Pedro Paulo de Andrade Santos; Marcelo Gadelha Vasconcelos; Karuza Maria Alves Pereira; Lélia Batista de Souza; Roseana de Almeida Freitas; Antônio de Lisboa Lopes Costa; Ana Myriam Costa de Medeiros

    2007-01-01

    A hiperplasia epitelial focal, ou doença de Heck, é uma enfermidade rara, benigna, que afeta a mucosa oral de crianças e adultos jovens de diversas regiões do mundo e em diferentes grupos étnicos, como indígenas e esquimós. Apresenta correlação com o papilomavírus humano (HPV) no qual os tipos 13 e 32 têm sido consistentemente detectados nessas lesões. Este artigo relata um caso de uma paciente de 18 anos de idade, descendente de índios potiguares, que compareceu ao serviço de estomatologia d...

  9. Punção aspirativa com agulha fina guiada por ultrassom e biópsia por videolaparoscopia em próstata de cães

    Directory of Open Access Journals (Sweden)

    T.M. Paula

    2011-08-01

    Full Text Available Onze cães, sem raça definida, machos, adultos, não castrados e hígidos foram submetidos à punção aspirativa com agulha fina da próstata guiada por ultrassom para avaliação citológica e, após um período mínimo de sete dias, à videolaparoscopia para obtenção de fragmento prostático para avaliação histológica. Nos exames citológicos, dois animais apresentaram alterações celulares compatíveis com hiperplasia prostática benigna. Durante a videolaparoscopia, a colheita do fragmento prostático foi realizada de maneira rápida, não sendo observada hemorragia significativa após o procedimento. Os animais não apresentaram nenhuma complicação no período pós-operatório. Verificaram-se, ao exame histológico, morfologia e estrutura celulares e teciduais nos padrões normais do parênquima prostático em 10 animais; um único cão apresentou alterações celulares e teciduais sugestivas de hiperplasia prostática benigna.

  10. Human Gingival Crevicular Fluids (GCF) Proteomics: An Overview

    OpenAIRE

    Zohaib Khurshid; Maria Mali; Mustafa Naseem; Shariq Najeeb; Muhammad Sohail Zafar

    2017-01-01

    Like other fluids of the human body, a gingival crevicular fluid (GCF) contains proteins, a diverse population of cells, desquamated epithelial cells, and bacteria from adjacent plaque. Proteomic tools have revolutionized the characterization of proteins and peptides and the detection of early disease changes in the human body. Gingival crevicular fluids (GCFs) are a very specific oral cavity fluid that represents periodontal health. Due to their non-invasive sampling, they have attracted pro...

  11. A rare case of unusual gingival enlargement post radiotherapy

    OpenAIRE

    Vishal Singh; G Subraya Bhat; K Mahalinga Bhat

    2011-01-01

    Oral changes following radiotherapy are not uncommon. Oral mucositis, alteration in salivary gland function, radiation caries, and gingival changes have all been reported following radiotherapy and chemotherapy. The gingival changes seen after radiotherapy may be unusual and often cause diagnostic dilemma. Metastasis to the gingiva has also to be ruled out in these cases. A 30-year-old female patient presented with enlargement of the gingiva of 6 months? duration and lower lip swelling of 7 m...

  12. Prevention of gingival trauma: Oral hygiene devices and oral piercings

    OpenAIRE

    Hoenderdos, N.L.

    2017-01-01

    Maintaining healthy teeth and soft oral tissues for life is important. Oral hygiene devices and oral piercings can damage the soft oral tissues. This thesis investigates the safety of manual toothbrushes, interdental brushes and rubber bristles interdental cleaners by analysing the gingival abrasion score. The efficacy of the various oral hygiene devices is measured by the use of dental plaque scores and gingivitis scores. In addition, the prevalence, the short- and long-term effects and the ...

  13. Experimental gingivitis, bacteremia and systemic biomarkers: a randomized clinical trial.

    Science.gov (United States)

    Kinane, D F; Zhang, P; Benakanakere, M; Singleton, J; Biesbrock, A; Nonnenmacher, C; He, T

    2015-12-01

    Bacteremia and systemic inflammatory markers are associated with periodontal and systemic diseases and may be linking mechanisms between these conditions. We hypothesized that in the development of gingival inflammation, systemic markers of inflammation and bacteremia would increase. To study the effect of bacteremia on systemic inflammatory markers, we recruited 80 subjects to participate in an experimental gingivitis study. Subjects were stratified based on gender, smoking and the number of bleeding sites and then randomized to one of two groups: control group (n = 40) or experimental gingivitis group (n = 40). Subjects in the control group conducted an oral hygiene regimen: brushing twice daily with a regular sodium fluoride cavity protection dentifrice and a standard manual toothbrush, flossing twice daily, and mouth rinsing with an anti-cavity fluoride rinse once daily. The experimental group stopped brushing and flossing, and used only the fluoride anti-cavity mouth rinse for 21 d. Seventy-nine of 80 subjects were evaluable. One subject in the control group was excluded from the results due to antibiotic use during the study. Our data showed the experimental gingivitis group exhibited a significant (p gingival inflammatory indices relative to baseline and the control group but a decrease in bacteremia and soluble intercellular adhesion molecule-1 levels vs. baseline. Bacteremia was negatively correlated with gingival inflammatory indices and soluble intercellular adhesion molecule-1 levels in the experimental gingivitis group, thus negating our hypothesis. We conclude that there are marked differences in systemic cytokine levels over the course of short-term experimentally induced gingivitis and further conclude that a long-term periodontitis study must be considered to address mechanisms whereby oral diseases may affect systemic diseases. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  14. Risk factors for gingivitis in a group of Brazilian schoolchildren.

    Science.gov (United States)

    Chiapinotto, Fabiana Amaral; Vargas-Ferreira, Fabiana; Demarco, Flávio Fernando; Corrêa, Fernanda Oliveira Bello; Masotti, Alexandre Severo

    2013-01-01

    Studies on gingivitis in children and adolescents are scarce and the results are inconclusive. The aim of this study was to assess the prevalence and extension of gingivitis and associated factors in Brazilian schoolchildren. Cross-sectional data from 1,211 schoolchildren 8 to 12 years old from Southern Brazil in 20 public and private schools were analyzed. Socioeconomic, demographic, and oral hygiene habits were assessed by questionnaires answered by parents and children. Buccal examination assessed presence of plaque, crowding, and gingivitis. Data were analyzed using Poisson regression [prevalence ratio (PR); 95% confidence interval (CI)]. Prevalence of visible plaque was 89.7% (95% CI 88.0-91.3) and gingival bleeding on probing was 78.4% (95% CI 76.1-81.0). The mean and median numbers of sites with gingival bleeding were 3.10 and 2 (SD ± 3.22), respectively. In multivariate adjusted analysis, the presence of a greater number of sites with plaque was significantly associated with gingivitis (PR 1.26; 95% CI 1.07-1.47) and its extension (PR 1.96; 95% CI 1.53-2.51). Lighter-skinned black children had a lower probability of having severe gingivitis (PR 0.69; 95% CI 0.48-0.98) compared with white children. This association was observed after adjusting for other variables. Gingivitis was associated with higher number of sites with plaque and with skin color, reflecting the influence of biological and demographic factors on this oral condition. © 2012 American Association of Public Health Dentistry.

  15. Forma no clásica de hiperplasia adrenal congénita en la niñez y adolescencia Non-classic way of congenital adrenal hyperplasia in childhood and adolescence

    Directory of Open Access Journals (Sweden)

    Francisco Carvajal Martínez

    2010-04-01

    Full Text Available INTRODUCCIÓN: la hiperplasia adrenal congénita es un trastorno hereditario de la esteroidogénesis suprarrenal, trasmitido por mutaciones genéticas con carácter autosómico recesivo, las cuales afectan las enzimas que intervienen en la biosíntesis del cortisol. La causa la constituye en 90 a 95 % de los casos la deficiencia de la enzima 21 hidroxilasa. OBJETIVO: exponer la experiencia de los autores de este trabajo en la forma no clásica de esta enfermedad. MÉTODOS: se realizó la caracterización de 7 pacientes diagnosticados en la sala de endocrinología pediátrica del Instituto Nacional de Endocrinología, ubicada en el Hospital Pediátrico del Cerro, durante el período 1998-2008. Todos los pacientes pertenecían al sexo femenino. RESULTADOS: los síntomas se iniciaron a una edad promedio de 8,8 años y más de la mitad de los casos presentaron pubarquia precoz. La menarquia se produjo a una edad media de 10,7 años. Se logró el diagnóstico bioquímico al obtenerse valores elevados de 17 hidroxiprogesterona (en condiciones basales. Se emplearon distintas modalidades de tratamiento según la edad de cada paciente y los síntomas predominantes en cada caso. CONCLUSIONES: se corroboró la mayor frecuencia de diagnóstico de esta enfermedad en el sexo femenino, así como la importancia del estudio y el seguimiento ante un paciente con pubarquia precoz.INTRODUCTION: the congenital adrenal hyperplasia is an inherited disorder of suprarenal esteroidogenesis, transmitted by genetic mutations with a autosomal recessive character affecting the enzymes intervening in cortisol biosynthesis. In the 90 to 95% of cases, the cause is a deficiency of Hydroxylase enzyme 21. OBJECTIVE: to show the current paper authors' experience in the non-classic way of this entity. METHODS: we made a characterization of 7 female patients diagnosed in the Children Endocrinology Ward of the National Institute of Endocrinology located in the Children Hospital, Cerro

  16. Orthodontic adhesives induce human gingival fibroblast toxicity and inflammation.

    Science.gov (United States)

    Huang, Tsui-Hsien; Liao, Pao-Hsin; Li, Han Yu; Ding, Shinn Jyh; Yen, Min; Kao, Chia-Tze

    2008-05-01

    To test the null hypothesis that the resin base and the resin hybrid glass ionomer base adhesives do not cause inflammation after contacting primary human gingival fibroblasts in vitro. The resin base and resin hybrid glass ionomer base adhesives were used to treat human gingival fibroblasts to evaluate the survival rate using MTT colorimetric assay to detect the level of cyclooxygenase-2 (COX-2) mRNA by reverse transcription polymerase chain reaction (RT-PCR) technique and COX-2 protein expression using Western blot analysis. The results were analyzed using one-way analysis of variance (ANOVA). Tests of differences of the treatments were analyzed using the Tukey test and a value of P adhesive and the liquid of glass ionomer adhesive showed decreasing survival rates after 24 hours of treatment (P adhesives induced COX-2 protein expression in human gingival fibroblasts. The exposure of quiescent human gingival fibroblasts to adhesives resulted in the induction of COX-2 mRNA expression. The investigations of the time-dependent COX-2 mRNA expression in adhesive-treated human gingival fibroblasts revealed different patterns. The hypothesis is rejected. For orthodontic patients with gingival inflammation, except for those with oral hygiene problems, the activation of COX-2 expression by orthodontic adhesive may be one of the potential mechanisms.

  17. Orthodontic therapy and gingival recession: a systematic review.

    Science.gov (United States)

    Joss-Vassalli, I; Grebenstein, C; Topouzelis, N; Sculean, A; Katsaros, C

    2010-08-01

    To perform a systematic review on the effect of changes in incisor inclination owing to orthodontic treatment and the occurrence of gingival recession. PubMed, EMBASE Excerpta Medica and CENTRAL of the Cochrane Library were searched and a hand search was performed. From 1925 articles identified, 17 articles were finally included: six experimental animal studies and 11 retrospective clinical studies in humans. More proclined teeth compared with less proclined teeth or untreated teeth had in most studies a higher occurrence or severity of gingival recession. Contradictory results were found regarding a possible statistically significant correlation between the extent of gingival recession and the amount of incisor proclination during treatment, width of attached gingiva, hygiene, periodontal condition or thickness of the symphysis. There are no high quality animal or clinical studies on this topic. Movement of the incisors out of the osseous envelope of the alveolar process may be associated with a higher tendency for developing gingival recessions. The amount of recession found in studies with statistically significant differences between proclined and non-proclined incisors is small and the clinical consequence questionable. Because of the low level of evidence of the included studies, the results should be considered with caution. Further randomized clinical studies including clinical examination of hygiene and gingival condition before, during and after treatment are needed to clarify the effect of orthodontic changes in incisor inclination and the occurrence of gingival recession.

  18. Original Research. The Influence of Desquamative Gingivitis on Periodontal Health

    Directory of Open Access Journals (Sweden)

    Monea Monica

    2017-03-01

    Full Text Available Background: Desquamative gingivitis (DG is a non-plaque-induced, blistering and painful condition occurring most frequently on the labial aspect of the attached gingiva of anterior teeth. The incidence of DG is highest around 50 years of age, and usually indicates the presence of oral or systemic diseases. The purpose of our study was to determine the impact of DG on periodontal health by recording the plaque index, gingival index and gingival bleeding index in a group of patients with DG, compared to healthy controls. Materials and methods: Recordings of specific indices were performed in a group of 26 patients with DG and compared with 24 healthy individuals. These were followed by radiographic examinations in order to assess the loss of marginal alveolar bone. Results: The results showed that patients with DG had a statistically significant increase in periodontal indices, with more gingival inflammation and plaque retention compared to the control group (p <0.05. The highest scores for gingival inflammation were recorded in patients with DG, but on radiographic evaluation the difference was related only to gender, men being more affected by alveolar bone loss in both groups (p <0.05. Conclusions: The incidence and severity of gingival inflammation proved to be higher in patients with DG, which calls for better preventive and maintenance treatment protocols in this group of patients. Early diagnosis and initial-phase periodontal treatment are very important in preventing further tissue breakdown.

  19. Smoking influences on the thickness of marginal gingival epithelium

    Directory of Open Access Journals (Sweden)

    Villar Cristina Cunha

    2003-01-01

    Full Text Available Smoking patients show reduction of inflammatory clinical signs that might be associated with local vasoconstriction and an increased gingival epithelial thickness. The purpose of this work was to evaluate the thickness of the marginal gingival oral epithelium in smokers and non-smokers, with clinically healthy gingivae or with gingivitis. Twenty biopsies were obtained from four different groups. Group I: non-smokers with clinically healthy gingivae (n = 5. Group II: non-smokers with gingivitis (n = 5. Group III: smokers with clinically healthy gingivae (n = 5. Group IV: smokers with gingivitis (n = 5. These biopsies were histologically processed, serially sectioned at 5 mm, stained with H. E., and examined by image analysis software (KS400, which was used to perform the morphometric evaluation and the quantification of the major epithelial thickness, the epithelial base thickness and the external and internal epithelial perimeters. Differences between the four groups were analyzed using ANOVA test and Tukey's test. The criteria for statistical significance were accepted at the probability level p < 0.05. A greater epithelial thickness was observed in smokers independent of the gingival health situation.

  20. DIFFERENTIAL HISTOMORPHOMETRIC CHANGES IN NORMAL AND INFLAMED GINGIVAL EPITHELIUM

    Directory of Open Access Journals (Sweden)

    Tanaskovic Stankovic Sanja

    2016-12-01

    Full Text Available Introduction and aim: In recent decades, many factors such as smoking, unhealthy diet as well as high alcohol intake were marked as risk factors that can lead to increased incidence of malignant alterations, gingivitis, periodontal disease and other oral epithelium pathological changes. Having in mind that in the group of non-malignant and non-dental oral pathology gingivitis and periodontal disease are the most common oral mucosa alterations aim of our research was to investigate histomorphometric characteristics of healthy and altered oral and gingival epithelium. Material and methods: Tissue samples of 24 oral and gingival mucosa specimens were collected. Samples were fixed in 10% buffered paraformaldehyde, routinely processed and embedded in paraffin blocks. From each block sections 5 micrometer thin were made and standard H/E staining as well as immunocytochemical detection of Ki-67 proliferation marker and CD79a lymphocyte marker were performed. Measurements and image analysis was performed with Image Pro Plus software (Media Cybernetics, USA and Axiovision (Ziess, USA. Results: We showed that inflamed gingival epithelium is increasing its thickness in proportion to the severity of adjacent inflammation. Furthermore, mitotic index is rising (up to 132% in the same manner as well as basal lamina length (up to 70% when normal and inflamed gingiva is compared. Architecture of epithelial ridges is changed from straightforward to mesh-like. Conclusion: Assessment of the free gingival epithelium thickness is directly related to the severity of the inflammation process i

  1. Treatment of gingival hyperpigmentation by open spray cryotherapy

    Directory of Open Access Journals (Sweden)

    Belkız Uyar

    2013-03-01

    Full Text Available Background and Design: Although gingival hyperpigmentation is not a medical problem, people who have moderate or severe gingival pigmentation, particularly patients having a gummy smile, frequently request cosmetic treatment. For gingival depigmentation, different treatment modalities have been reported such as surgical treatment, cryotherapy, electrosurgery, and laser therapy. Materials and Methods: Twenty-one patients with gingival melanin pigmentation were included in the study. We applied liquid nitrogen to the hyperpigmented area for 5-10 seconds using open spray technique with a cryogun. Clinical observations for intensity of pigmentation were recorded at baseline and 3 months after the treatment. Clinical parameters, such as bleeding, swelling, redness, and healing, were evaluated immediately after the cryotherapy and 24 hours, and 1 week after the treatment. We used a numeric pain scale to evaluate the pain level. Results: Three months after the treatment, the mean gingival melanin pigmentation score decreased from 41.62±16.58 to 19.28±11.85. The difference between pretreatment and posttreatment mean scores was found to be statistically significant.Discussion: Removal of gingival melanin pigmentation can be performed safely by open spray cryotherapy in dermatology clinics.

  2. Effect of Sleep and Salivary Glucose on Gingivitis in Children.

    Science.gov (United States)

    Alqaderi, H; Tavares, M; Hartman, M; Goodson, J M

    2016-11-01

    It has been shown that inadequate sleep has deleterious effects on health by suppressing immunity and promoting inflammation. The aim of this study was to investigate the effect of sleep and salivary glucose levels on the development of gingivitis in a prospective longitudinal study of Kuwaiti children. Data were collected from 10-y-old children ( N = 6,316) in 2012 and again in 2014. Children were approximately equally distributed from 138 elementary schools representing the 6 governorates of Kuwait. Calibrated examiners conducted oral examination, self-reported sleep evaluation interviews, anthropomorphic measurements, and unstimulated whole saliva sample collection. Salivary glucose levels were measured by a florescent glucose oxidase method; values of salivary glucose ≥1.13 mg/dL were defined as high glucose levels. A multilevel random intercept and slope analysis was conducted to determine the relationship between sleep duration and gingivitis on 3 levels: within schools, among children, and over time. The outcome was the progression of the extent of gingival inflammation in children over time. The main independent variables were the number of daily sleep hours and salivary glucose levels. Other explanatory variables and confounders assessed were governorate, dental caries and restorations, and obesity by waist circumference (adjusted for snacking and sex). Gingivitis increased over time in children who had shorter sleep duration ( P glucose levels >1.13 mg/dL predicted gingivitis ( P glucose levels were both associated with increased gingival inflammation.

  3. Microbiota-based Signature of Gingivitis Treatments: A Randomized Study.

    Science.gov (United States)

    Huang, Shi; Li, Zhen; He, Tao; Bo, Cunpei; Chang, Jinlan; Li, Lin; He, Yanyan; Liu, Jiquan; Charbonneau, Duane; Li, Rui; Xu, Jian

    2016-04-20

    Plaque-induced gingivitis can be alleviated by various treatment regimens. To probe the impacts of various anti-gingivitis treatments on plaque microflora, here a double blinded, randomized controlled trial of 91 adults with moderate gingivitis was designed with two anti-gingivitis regimens: the brush-alone treatment and the brush-plus-rinse treatment. In the later group, more reduction in both Plaque Index (TMQHI) and Gingival Index (mean MGI) at Day 3, Day 11 and Day 27 was evident, and more dramatic changes were found between baseline and other time points for both supragingival plaque microbiota structure and salivary metabonomic profiles. A comparison of plaque microbiota changes was also performed between these two treatments and a third dataset where 50 subjects received regimen of dental scaling. Only Actinobaculum, TM7 and Leptotrichia were consistently reduced by all the three treatments, whereas the different microbial signatures of the three treatments during gingivitis relieve indicate distinct mechanisms of action. Our study suggests that microbiota based signatures can serve as a valuable approach for understanding and potentially comparing the modes of action for clinical treatments and oral-care products in the future.

  4. Predictive modeling of gingivitis severity and susceptibility via oral microbiota.

    Science.gov (United States)

    Huang, Shi; Li, Rui; Zeng, Xiaowei; He, Tao; Zhao, Helen; Chang, Alice; Bo, Cunpei; Chen, Jie; Yang, Fang; Knight, Rob; Liu, Jiquan; Davis, Catherine; Xu, Jian

    2014-09-01

    Predictive modeling of human disease based on the microbiota holds great potential yet remains challenging. Here, 50 adults underwent controlled transitions from naturally occurring gingivitis, to healthy gingivae (baseline), and to experimental gingivitis (EG). In diseased plaque microbiota, 27 bacterial genera changed in relative abundance and functional genes including 33 flagellar biosynthesis-related groups were enriched. Plaque microbiota structure exhibited a continuous gradient along the first principal component, reflecting transition from healthy to diseased states, which correlated with Mazza Gingival Index. We identified two host types with distinct gingivitis sensitivity. Our proposed microbial indices of gingivitis classified host types with 74% reliability, and, when tested on another 41-member cohort, distinguished healthy from diseased individuals with 95% accuracy. Furthermore, the state of the microbiota in naturally occurring gingivitis predicted the microbiota state and severity of subsequent EG (but not the state of the microbiota during the healthy baseline period). Because the effect of disease is greater than interpersonal variation in plaque, in contrast to the gut, plaque microbiota may provide advantages in predictive modeling of oral diseases.

  5. Oral health education and therapy reduces gingivitis during pregnancy.

    Science.gov (United States)

    Geisinger, Maria L; Geurs, Nicolaas C; Bain, Jennifer L; Kaur, Maninder; Vassilopoulos, Philip J; Cliver, Suzanne P; Hauth, John C; Reddy, Michael S

    2014-02-01

    Pregnant women demonstrate increases in gingivitis despite similar plaque levels to non-pregnant counterparts. To evaluate an intensive protocol aimed at reducing gingivitis in pregnant women and provide pilot data for large-scale randomized controlled trials investigating oral hygiene measures to reduce pregnancy gingivitis and alter maternity outcomes. One hundred and twenty participants between 16 and 24 weeks gestation with Gingival Index (GI) scores ≥2 at ≥50% of tooth sites were enrolled. Plaque index (PI), gingival inflammation (GI), probing depth (PD), and clinical attachment levels (CAL) were recorded at baseline and 8 weeks. Dental prophylaxis was performed at baseline and oral hygiene instructions at baseline, 4 and 8 weeks. Pregnancy outcomes were recorded at parturition. Mixed-model analysis of variance was used to compare clinical measurements at baseline and 8 weeks. Statistically significant reductions in PI, GI, PD, and CAL occurred over the study period. Mean whole mouth PI and GI scores decreased approximately 50% and the percentage of sites with PI and GI ≥2 decreased from 40% to 17% and 53% to 21.8%, respectively. Mean decreases in whole mouth PD and CAL of 0.45 and 0.24 mm, respectively, were seen. Intensive oral hygiene regimen decreased gingivitis in pregnant patients. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  6. Chronic gingivitis: the prevalence of periodontopathogens and therapy efficiency.

    Science.gov (United States)

    Igic, M; Kesic, L; Lekovic, V; Apostolovic, M; Mihailovic, D; Kostadinovic, L; Milasin, J

    2012-08-01

    The purpose of this study was to determine the level of gingival inflammation and the prevalence of periodontopathogenic microorganisms in adolescents with chronic gingivitis, as well as to compare the effectiveness of two approaches in gingivitis treatment-basic therapy alone and basic therapy + adjunctive low-level laser therapy (LLLT). After periodontal evaluation, the content of gingival pockets of 140 adolescents with gingivitis was analyzed by multiplex PCR for the presence of P. gingivalis, A. actinomycetemcomitans, T. forsythensis and P. intermedia. Subsequent to bacteria detection, the examinees were divided into two groups with homogenous clinical and microbiological characteristics. Group A was subjected to basic gingivitis therapy, and group B underwent basic therapy along with adjunctive LLLT. A statistically significant difference between the values of plaque-index (PI) and sulcus bleeding index (SBI) before and after therapy was confirmed in both groups (pgingivitis should be regarded as a sign for dentists to foster more effective oral health programs. LLLT appears to be beneficial as adjuvant to basic therapy.

  7. Gingival augmentation procedure prior to fixed orthodontic treatment

    Directory of Open Access Journals (Sweden)

    Surekha Bhedasgoankar

    2011-01-01

    Full Text Available Patients seek orthodontic treatment for correction of malocclusion and aesthetic improvement. A strong correlation between labially placed teeth and gingival recession has been found. If such cases are left untreated with or without orthodontic therapy, it may lead to an increase in the severity of the disease. A similar case of a 21-year-old male patient with gingival recession in the mandibular anterior region is reported. The patient was successfully treated using a free gingival graft technique. This technique not only improves the aesthetic aspect but also avoids future attachment loss and thus makes the patient more stable for further orthodontic treatment. The aim behind the treatment of gingival recession is not only to cover the exposed root surface, but also to improve aesthetics and reduce dentinal hypersensitivity. Different soft tissue-grafting procedures have been proposed for the treatment of gingival recession, of which free gingival graft is the most reliable one. The purpose of this case report is to illustrate the importance of root coverage prior to orthodontic treatment and to describe the planning for successful treatment which will improve the overall periodontal status of the patient.

  8. Oral prophylactic procedures and gingival health among Nigerian school children.

    Science.gov (United States)

    Sote, E O

    1991-01-01

    Various researchers have advocated the use of chewing sticks in community oral health programmes because they are readily available, cheaper than the toothbrush and paste, and are found to possess antiplaque properties. Oral health education is essential for enlightenment on good oral health maintenance. The study was thus aimed at educating children on how to maintain a good oral health (including the efficient use of various oral hygiene implements) and noting the impact on their gingival health. 120 school children with no gingival disease, aged 12 to 14 years, participated in the study. They were all examined intra-orally and their plaque scores were recorded. After two weeks of oral health education programmes, they were randomly assigned into three equal groups, each group using either the toothbrush/paste, the Massularia acuminata chewing stick or the Sorindeia warneckei chewing stick for three months. Their plaque scores and gingivitis incidence were recorded. 36.0% had gingivitis, 2.0% had periodontitis with pocketing greater than or equal to 5 mm, and about 3.0% had gingival recession. More toothbrush users than the chewing stick users in the study had gingivitis (P less than .05). The inherent danger in introducing unfamiliar oral hygiene procedures to children without close monitoring is highlighted. Whatever mode of oral hygiene is adopted for use in children, adequate supervision by knowledgeable parents and teachers, and close monitoring by oral health personnel is mandatory in order to ensure effective use.

  9. Evaluación de los efectos del tratamiento con tadalafilo sobre las funciones cerebrales, neurológicas y bioquímicas en pacientes con hiperplasia benigna de próstata y disfunción eréctil

    OpenAIRE

    Ordoño Domínguez, Felipe

    2015-01-01

    EVALUACION DE LOS EFECTOS DEL TRATAMIENTO CON TADALAFILO SOBRE LAS FUNCIONES CEREBRALES, NEUROLOGICAS Y BIOQUIMICAS EN PACIENTES CON HBP Y DISFUNCION ERECTIL. La hiperplasia prostática benigna (HBP) es una de las enfermedades benignas más comunes en el hombre y puede derivar en una hipertrofia benigna de la próstata, en una obstrucción benigna de la próstata y/o en síntomas del tracto urinario inferior (STUI). La hiperplasia benigna de próstata suele estar asociada habitualmente con disfu...

  10. Smoking and gingivitis: focus on inducible nitric oxide synthase, nitric oxide and basic fibroblast growth factor.

    Science.gov (United States)

    Özdemir, B; Özmeric, N; Elgün, S; Barış, E

    2016-10-01

    Periodontal disease pathogenesis has been associated with smoking. Gingivitis is a mild and reversible form of periodontal disease and it tends to progress to periodontitis only in susceptible individuals. In the present study, we aimed to examine the impact of smoking on host responses in gingivitis and to evaluate and compare the inducible nitric oxide synthase (iNOS) activity in gingival tissue and NO and basic fibroblast growth factor (bFGF) levels in the gingival crevicular fluid of patients with gingivitis and healthy individuals. Forty-one participants were assigned to the gingivitis-smoker (n = 13), gingivitis (n = 13), healthy-smoker (n = 7) and healthy groups (n = 8). Clinical indices were recorded; gingival biopsy and gingival crevicular fluid samples were obtained from papillary regions. iNOS expression was evaluated by immunohistochemical staining. The immunoreactive cells were semiquantitatively assessed. For the quantitative determination of nitrite and nitrate in gingival crevicular fluid, the NO assay kit was used. The amount of bFGF in gingival crevicular fluid was determined by enzyme-linked immunosorbent assay. The gingivitis-smoker group demonstrated a stronger iNOS expression than the non-smoker gingivitis group. iNOS expression intensity was lower in the non-smoker healthy group compared to that in healthy-smokers. No significant gingival crevicular fluid NO and bFGF level changes were observed between groups. Among patients with gingivitis, a positive correlation was detected between gingival crevicular fluid NO and bFGF levels (r = 0.806, p = 0.001). Our data suggest that smoking has significant effects on iNOS expression but not on gingival crevicular fluid NO or bFGF levels in healthy and patients with gingivitis. However, our results suggest that bFGF might be involved in the regulation of NO production via iNOS. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  11. Microbiological profile and calprotectin expression in naturally occurring and experimentally induced gingivitis.

    Science.gov (United States)

    Farina, Roberto; Guarnelli, Maria Elena; Figuero, Elena; Herrera, David; Sanz, Mariano; Trombelli, Leonardo

    2012-10-01

    This study was performed to evaluate the microbiological profile and the calprotectin expression in gingival crevicular fluid (GCF) in spontaneous and experimentally induced gingival inflammation. Thirty-seven periodontally healthy subjects were evaluated in real life conditions (N-O gingivitis) as well as after 21 days of experimental gingivitis trial (E-I gingivitis). During the experimental gingivitis trial, in one maxillary quadrant (test quadrant), gingival inflammation was induced by oral hygiene abstention, while in the contralateral (control) quadrant, oral hygiene was routinely continued. The results of the study showed that (1) the microbiological profile of quadrants where gingival inflammation was experimentally induced (i.e., E-I test quadrants) differed significantly from that of either quadrants where gingival inflammation was controlled by proper plaque control (i.e., E-I control quadrants) or quadrants with N-O gingivitis, and (2) GCF calprotectin was significantly higher at E-I test quadrants compared to either E-I control quadrants or quadrants with N-O gingivitis. A positive intrasubject correlation was found between GCF concentration of calprotectin at sites presenting N-O and E-I gingivitis. N-O and E-I gingivitis showed a different microbiological profile of the subgingival environment. GCF calprotectin is a reliable marker of gingival inflammation, and its concentration in N-O gingivitis is correlated with its expression in E-I gingivitis. The modality of plaque accumulation seems to affect the subgingival microbiological profile associated with a gingivitis condition. Calprotectin levels in GCF may be regarded as a promising marker of the individual susceptibility to develop gingival inflammation in response to experimentally induced plaque accumulation.

  12. Gingival changes during pregnancy: III. Impact of clinical, microbiological, immunological and socio-demographic factors on gingival inflammation.

    Science.gov (United States)

    Carrillo-de-Albornoz, Ana; Figuero, Elena; Herrera, David; Cuesta, Pedro; Bascones-Martínez, Antonio

    2012-03-01

    To identify predictor variables involved in exacerbated gingival inflammation associated with pregnancy. In this cohort study, 48 pregnant and 28 non-pregnant women without periodontitis were included. The pregnant women were evaluated in the first, second and third trimester and at 3 months postpartum, whilst the non-pregnant women were evaluated twice, with a 6-month interval. At each visit, clinical [plaque index (PlI) and gingival index (GI)], hormonal (salivary progesterone and estradiol), immunological [gingival crevicular fluid interleukin-1β, interleukin-6, tumour necrosis factor-α (TNF-α) and prostaglandin-E(2) ] and microbiological (periodontal pathogens culture) evaluations were performed. Statistical analysis was undertaken using exhaustive chi-square automatic interaction detection (exhaustive CHAID) to analyse the predictive value of the independent outcomes to develop pregnancy GI. PlI was the strongest predictor implicated in the GI throughout pregnancy and after delivery. During the second and third trimesters the presence of Porphyromonas gingivalis significantly contributed to the worsening of gingival inflammation. When compared with the non-pregnant group, significant differences were found in TNF-α amounts and concentrations and in the third trimester site-specific GI. Bacterial challenge to the gingival tissues, both quantitatively (PlI) and qualitatively (harbouring P. gingivalis) appears to affect the level of gingival inflammation observed during pregnancy. © 2011 John Wiley & Sons A/S.

  13. Changes in Gingival Crevicular Fluid Inflammatory Mediator Levels during the Induction and Resolution of Experimental Gingivitis in Humans

    Science.gov (United States)

    Offenbacher, Steven; Barros, Silvana; Mendoza, L; Mauriello, S; Preisser, J; Moss, K; de Jager, Marko; Aspiras, Marcelo

    2010-01-01

    Aim The goal of this study is to characterize the changes in 33 biomarkers within the gingival crevicular fluid during the 3-week induction and 4-week resolution of stent-induced, biofilm overgrowth mediated, experimental gingivitis in humans. Methods Experimental gingivitis was induced in 25 subjects for 21 days followed by treatment with a sonic powered toothbrush for 28 days. Clinical indices and gingival crevicular fluids were collected weekly during induction and biweekly during resolution. Samples were analyzed using a bead-based multiplexing analysis for the simultaneous measurements of 33 biomarkers within each sample including cytokines, matrix-metalloproteinases and adipokines. Prostaglandin-E2 was measured by enzyme-linked immunoadsorbant assay. Statistical testing using general linear models with structured covariance matrices were performed to compare stent to contralateral (non-stent) changes in clinical signs and in biomarker levels over time. Results Gingivitis induction was associated with a significant 2.6-fold increase in interleukin 1-beta, a 3.1 fold increase in interleukin 1-alpha, and a significant decrease in multiple chemokines as well as matrixmetalloproteinases −1, −3 and 13. All changes in clinical signs and mediators rebounded to baseline in response to treatmentin the resolution phase. Conclusions Stent-induced gingivitis is associated with marked, but reversible increases in interleukins 1-alpha and 1-beta with suppression of multiple chemokines as well as selected matrixmetalloproteinases. PMID:20447255

  14. Doença de Kimura não é hiperplasia angiolinfóide com eosinofilia: correlação clinicopatológica com revisão da literatura e definição de critérios diagnósticos Kimura disease is not angiolymphoid hyperplasia with eosinophilia: clinical and pathological correlation with literature review and definition of diagnostic criteria

    Directory of Open Access Journals (Sweden)

    Pedro Leonardo Briggs

    2006-03-01

    Full Text Available A doença de Kimura é doença inflamatória crônica que se manifesta como crescimento tumoral indolor na região da cabeça e do pescoço, freqüentemente associada à linfoadenopatia cervical. Por ser doença rara, ter sido descrita inicialmente na literatura oriental e ter características em comum com a hiperplasia angiolinfóide com eosinofilia, a doença de Kimura tem sido confundida com essa enfermidade, da qual deve ser distinguida. Neste artigo, revisam-se as características clínicas e histopatológicas e apresentam-se critérios para a diferenciação dessas duas entidades.Kimura disease is a rare chronic inflammatory disease that presents as a tumor-like swelling in the head and neck region and is often associated with regional cervical lymphadenopathy. Cases have been described predominantly in the oriental literature. Kimura disease has been confused with angiolymphoid hyperplasia with eosinophilia, for having common characteristics, but both conditions should be differentiated. In this article, the clinical and histopathological characteristics are revised and the criteria to differentiate the two conditions are presented.

  15. PERCEPCIÓN Y EXPERIENCIAS FRENTE A LA HIPERPLASIA EPITELIAL FOCAL EN UNA COMUNIDAD INDÍGENA HUITOTO/TICUNA DEL AMAZONAS COLOMBIANO Knowledge, attitude, and practices about focal epithelial hyperplasia in the Huitoto/Ticuna native community of Colombian Amazon

    Directory of Open Access Journals (Sweden)

    Mauricio Rodríguez G

    2008-06-01

    Full Text Available Antecedentes . La hiperplasia epitelial focal, es una enfermedad frecuente en ciertas comunidades indígenas, es producida por un tipo de virus, en la que además parecen participar algunos otros factores socio-demográficos en su desarrollo y presentación. Objetivo. Explorar los conocimientos, actitudes y prácticas de una comunidad indígena Huitoto Ticuna del Amazonas sobre la hiperplasia epitelial focal. Material y métodos. De acuerdo a la presentación de los casos por familia, se diseñó una guía de entrevista considerando: percepción del problema, experiencias previas, impacto y manejo de las lesiones. Se escogieron 10 viviendas con casos positivos realizando entrevistas semiestruc-turadas y un análisis por subtópicos y por dominios, se aplicó metodología cualitativa para la obtención de la información, dentro de un estudio descriptivo. Resultados. Participaron tres hombres y nueve mujeres; 11 pertenecían a la etnia Ticuna y una a la etnia Yagua. Los entrevistados se encontraron entre 17 y 46 años. Sólo dos casos se reportaron en niñas, el resto fueron reportados en niños, cuyas edades oscilaban entre los dos y ocho años. La lesión es conocida por la comunidad, pero para ellos no constituye un problema importante, ya que aparte de la implicación estética, no ocasiona sintomatología que interfiera de forma importante con su vida cotidiana. Consideran que la enfermedad se produce por contacto con elementos contaminados, niegan la posibilidad de contagio persona a persona. Para el tratamiento utilizan sustancias, como sal y ceniza, raspan las lesiones considerando que al salir la sangre, sale la enfermedad y además aplican tópicamente sustancias referidas por ellos como resinas vegetales. Conclusiones. Como mecanismo etiológico principal refieren el contagio por medio de vectores, buscan eliminar la enfermedad por el aspecto estético; conocen métodos naturales para el tratamiento de estas lesiones, estos se

  16. Gingival pyogenic granuloma developing during isotretinoin treatment

    Directory of Open Access Journals (Sweden)

    Engin Şenel

    2014-12-01

    Full Text Available Pyogenic granuloma (PG is a rare side effect of isotretinoin therapy. Oral pyogenic granuloma developing during isotretinoin treatment has not been reported so far. A 22-old-male patient, who had been given oral isotretinoin treatment for severe nodular acne, was admitted with the complaint of a painless and red nodule in his lower gum at the end of the second month of the treatment. The patient did not report any history of trauma or dental treatment. Dermatologic examination revealed a hemorrhagic nodule measuring 1.5x1 cm in size in the lower gums of the cutting and canine teeth. The lesion was excised completely. Histopathological examination disclosed acanthosis and hyperkeratosis in epidermis, subepidermal vascular proliferation, edema, and sparsely scattered inflammatory cell groups. The mechanism by which isotretinoin causes pyogenic granulomas is not exactly known. It should be considered that this rare side effect can be gingival in patients taking isotretinoin and the regular oral examination should not be neglected.

  17. Gingival recession is likely associated with tongue piercings.

    Science.gov (United States)

    Reynolds, Mark A

    2012-09-01

    A convenience sample of 60 subjects (27 male; 33 female) with tongue piercings (case group) and 120 subjects (43 male; 77 female) without tongue piercings (control group), ranging in age from 13 to 28 years, were identified from a mix of races living in a geographic area of low socioeconomic status in Brazil. Subjects were recruited from school groups and university centers between January 2008 and March 2009. For each case, 2 controls were selected on a consecutive basis from the same school according to criteria that included age, gender, smoking, and previous orthodontic treatment. Exclusion criteria included individuals with systemic diseases that might compromise the immune system, as well as antibiotics within 3 months or other medications that could affect the gingival tissues. The key study factor was the use or nonuse of tongue piercings (jewelry). The analysis compared periodontal parameters, such as the occurrence, location, and severity of gingival recession, in subjects with and without tongue jewelry. Gingival recession in the anterior lingual mandibular region was assessed as the primary outcome measure. The study sample was divided according to the presence or absence of gingival recession as well as the severity (1-2, 3, and ≥ 4 mm) of gingival recession. The average age of subjects was similar in the case and control groups (18.9 versus 17.7 years, respectively). Fractures of the anterior teeth were present significantly more frequently in cases than controls (26.7% versus 11.7%, respectively; P gender, and the presence of bleeding on probing in the anterior region. Subjects with tongue jewelry exhibited an 18 times greater chance for the occurrence of gingival recession in the model (adjusted OR = 18.06, 95% CI 6.66-48.95, P < .001). The use of tongue jewelry was found to be strongly associated with the occurrence and severity of gingival recession in the mandibular anterior lingual region. Copyright © 2012. Published by Mosby, Inc. All rights

  18. Effect of essential oil mouthwashes on plaque and gingivitis.

    Science.gov (United States)

    Richards, Derek

    2017-06-23

    Data sourcesMedline, Embase, LILACS and Scopus database.Study selectionStudies were screened independently by three reviewers. Randomised controlled trials with a minimum of six months follow-up of daily use of essential oils-containing (EO) mouthwashes compared with placebo, flossing or cetylpyridinium chloride (CPC) as adjuncts to mechanical plaque control were considered.Data extraction and synthesisData were abstracted by two reviewers and study quality assessed using the Cochrane risk of bias tool. Dental plaque was summarised using the Turesky modification of the Quigley-Hein Index (QHI), gingivitis using three indices; the Gingival Index (GI) by Loe and Silness, the Modified Gingival Index (MGI) and bleeding upon probing. Mean and standard deviations were reported and meta-analysis conducted. Sources of effect modification were investigated using meta-regression.ResultsSixteen trials were included involving 4016 patients in total. Study quality was considered to be moderate to low. Compared with placebo meta-analysis of 14 studies showed statistically significant differences in favour of EO mouthwashes for plaque and gingival indices. Meta-analysis of four studies also demonstrated statistically lower levels of plaque and gingivitis for EO mouthwashes compared with cetylpyridium chloride (CPC). Meta-regression indicated that heterogeneity observed in plaque scores was mainly explained by the percentage of males in a trial and supervision of the mouthwash use.ConclusionsIn patients with gingivitis, EO-containing mouthwashes are more efficacious for the reduction of plaque and gingival inflammation than mechanical plaque control either alone (placebo) or in combination with mouthwashes with CPC. The expected benefits may be clinically relevant and may be also observed in the interproximal area.

  19. Evaluation of pain on use of electrosurgery and diode lasers in the management of gingival hyperpigmentation: A comparative study

    National Research Council Canada - National Science Library

    Chandna, Shalu; Kedige, Suresh Dyamappa

    Gingival depigmentation is a periodontal plastic surgical procedure whereby the gingival hyperpigmentation is removed by various techniques such as electrosurgery, cryosurgery, abrasion with diamond bur and lasers...

  20. Retracción gingival e hiperestesia dentinal: Causas y prevención Gingival recession and dentine hypersensitivity

    Directory of Open Access Journals (Sweden)

    Jorge Sotres Vázquez

    2004-08-01

    Full Text Available Se realizó una investigación en 230 pacientes que acudieron a los Servicios de Prótesis y Periodoncia de la Clínica Estomatológica "Hermanos Gómez" durante el año 2002. Se les evaluó la presencia de retracción gingival, sus causas y la relación existente con la hiperestesia dentinal. Se determinó que el 17,3 % de los dientes examinados presentaron algún grado de retracción gingival. Las causas más frecuentes fueron ausencia de dientes antagonistas e inserciones frénicas anormales. Existió una estrecha relación entre la hiperestesia dentinal y la retracción gingival. No existieron diferencias significativas de retracción gingival según el sexo, pero sí con la edad, pues aumentó significativamente según aumentó la edad.A research study was performed on 230 patients who went to the Denture and Periodontics Service at "Hermanos Gómez" dental clinic in the year 2002. They were evaluated as to presence of gingival recession, its causes and its relation with dentine hypersensitity. It was determined that 17,3% of examined teeth presented with some level of gingival recession frequently caused by lack of opposite teeth and abnormal frenal insertions. Gingival recession did not show significant differences by sex but it did by age since it markedly increased with the age.

  1. Aberrant expression of glucagon receptors in adrenal glands of a patient with Cushing's syndrome and ACTH-independent macronodular adrenal hyperplasia Expresion aberrante de receptores de glucagón en tejido adrenal de un paciente con síndrome de Cushing e hiperplasia adrenal macronodular indedependiente de ACTH

    Directory of Open Access Journals (Sweden)

    Valeria de Miguel

    2010-06-01

    Full Text Available Adrenocorticotropin (ACTH independent bilateral macronodular adrenal hyperplasia (AIMAH is a rare cause of Cushing´s syndrome, characterized by bilateral adrenal lesions and excess cortisol production despite ACTH suppression. Cortisol synthesis is produced in response to abnormal activation of G-protein- coupled receptors, such as gastric inhibitory peptide, vasopressin, beta adrenergic agonists, LH/hCG and serotonin receptors. The aim of this study was to analyze the expression of glucagon receptors in adrenal glands from an AIMAH patient. A patient with ACTH-independent Cushing´s syndrome and bilateral macronodular adrenal hyperplasia was screened for altered activation of adrenal receptors by physiological (mixed meal and pharmacological (gonadotrophin releasing hormone, ACTH and glucagon tests. The results showed abnormally high levels of serum cortisol after stimulation with glucagon. Hypercortisolism was successfully managed with ketoconazole treatment. Interestingly, a 4-month treatment with a somatostatin analogue (octreotide was also able to reduce cortisol secretion. Finally, Cushing's syndrome was cured after bilateral adrenalectomy. Abnormal mRNA expression for glucagon receptor in the patient´s adrenal glands was observed by Real-Time PCR procedure. These results strongly suggest that the mechanism of AIMAH causing Cushing´s syndrome in this case involves the illicit activation of adrenal glucagon receptors. This is the first case reported of AIMAH associated with ectopic glucagon receptors.La hiperplasia adrenal macronodular bilateral independiente de ACTH (HAMIA es una causa infrecuente de Síndrome de Cushing, caracterizada por lesiones adrenales bilaterales, hipercortisolismo y ACTH plasmática suprimida. La síntesis de cortisol estaría regulada a través de ligandos de receptores asociados a proteína G que se expresan en forma aberrante en la corteza de las glándulas adrenales. El objetivo de este trabajo es analizar

  2. High salivary estrogen and risk of developing pregnancy gingivitis.

    Science.gov (United States)

    Gürsoy, Mervi; Gürsoy, Ulvi Kahraman; Sorsa, Timo; Pajukanta, Riitta; Könönen, Eija

    2013-09-01

    Estrogen regulates the cellular functions of several tissues that may disturb the host response against bacteria. The present aim is to evaluate the contribution of estrogen to the severity of gingival inflammation during pregnancy. Salivary estrogen levels from 30 pregnant and 24 non-pregnant females were related to their periodontal health parameters, including visible plaque index (VPI) and bleeding on probing (BOP) from six sites per tooth. The pregnant group was examined three times during pregnancy and twice during postpartum, and the non-pregnant group was examined three times, once per subsequent month. Salivary estrogen levels increased significantly during the second (P high estrogen and high VPI levels had the highest frequency of pregnancy gingivitis. During the second and third trimesters, simultaneously enhanced estrogen levels and VPI scores brought an additional risk of developing gingivitis compared with a high VPI score alone. The present findings suggest that, during pregnancy, the estrogen level determines the magnitude of gingival inflammation developed against microbial plaque at the gingival margin.

  3. Gingival fibroma versus verrucous leukoplakia – A clinical dilemma!!!

    Directory of Open Access Journals (Sweden)

    Renu Garg

    2016-01-01

    Full Text Available Gingival overgrowths found in the oral cavity are mostly due to reactive hyperplasia and rarely depict neoplastic nature. It is a challenge for the clinician to give final diagnoses of gingival overgrowth. Gingiva is a common site for various benign and malignant lesions. Oral cavity is an ideal niche for the manifestation of various precancerous and cancerous lesions. Fibrous growths present in the oral cavity include a varying group of reactive, precancerous, and cancerous conditions. This report describes a case of a 55-year-old male who clinically presented with a localized fibromatous gingival overgrowth in relation to lower left mandibular canine-premolar region that was diagnosed as a gingival fibroma associated with leukoplakia. On histopathological examination, it was diagnosed as a case of proliferative verrucous leukoplakia. Many a times, clinicians face dilemma while diagnosing an overgrowth as it is difficult to differentiate clinically. Hence, a thorough clinical knowledge and a pathologist's opinion become mandatory to give final diagnosis to such gingival overgrowths.

  4. Level of Salivary Uric Acid in Gingivitis and Periodontitis Patients

    Directory of Open Access Journals (Sweden)

    Muhammad Ihsan Rizal

    2017-09-01

    Full Text Available Background: Periodontal disease is common chronic adult condition. Antioxidants are present in the body fluid as protection against free radical. Uric acid is one of antioxidants that can be found in saliva. Moreover, the relationship among the antioxidant enzymes activities and clinical periodontal status were investigated. Objectives: The aim of the study was to observe uric acid level activities in the saliva of gingivitis and periodontitis patients. Methods: Six patients with gingivitis and six patients with periodontitis in Dental Hospital Trisakti University were included in the study. Clinical condition of each subject, the plaque index, and probing depth were determined. The salivary uric acid level was measured using the Folin-Wu method. Result: Salivary uric acid levels in the periodontitis patients with a mean ± SD  7.40 ± 0.31  (p = 0.004 were found to be higher compared to the gingivitis patients (mean ± SD = 6.84 ± 0.19. In addition, there were no significant differences in salivary uric acid levels between gender (p = 0.641. Conclusion: Uric acid levels in periodontitis patients were found to be higher than in gingivitis patients. Moreover, uric acid has more role on periodontitis than in gingivitis as an antioxidant agent.

  5. The effectiveness of propolis on gingivitis: a randomized controlled trial.

    Science.gov (United States)

    Bretz, Walter A; Paulino, Niraldo; Nör, Jacques E; Moreira, Alexandre

    2014-12-01

    A randomized, double-blind, controlled clinical trial was conducted to evaluate the effectiveness of a propolis rinse on induced gingivitis by using the co-twin study design. Twenty-one twin pairs (n=42) were enrolled in a gingivitis study with oral hygiene promotion (14 days) and gingivitis induction (21 days). During the gingivitis induction phase, one member of the twin pair was randomly assigned to a 2% typified propolis rinse, and the other was assigned a color-matched 0.05% sodium fluoride plus 0.05% cetylpyridinium chloride rinse (positive control). Patients rinsed twice daily with 20 mL for 30 seconds for 21 days. Gingivitis was measured on days -14 (baseline), 0 (after hygiene phase), and 21 (after no-hygiene phase) by using the Papillary Bleeding Score (PBS) and by standard digital imaging of the gum tissues (G-parameter). The 38 persons who completed the study (age 13-22 years) were well balanced according to PBS at baseline and G-parameter after the initial hygiene phase. After 21 days without oral hygiene, the propolis rinse and positive control rinse groups did not differ significantly for average PBS measurements or G-parameter. Use of a 2% typified propolis rinse was equivalent to a positive control rinse during a 21-day no-hygiene period.

  6. Endotoxemia and the host systemic response during experimental gingivitis

    Science.gov (United States)

    Wahaidi, Vivian Y.; Kowolik, Michael J.; Eckert, George J.; Galli, Dominique M.

    2011-01-01

    Aim To assess endotoxemia episodes and subsequent changes in serum inflammatory biomarkers using the experimental gingivitis model Materials and Methods Data from 50 healthy black and white adult males and females were compared for serum concentrations of endotoxin, and serum biomarkers [neutrophil oxidative activity, interleukin (IL)-1β, IL-6, IL-8, C-reactive protein, and fibrinogen] at baseline, at 3 weeks of experimental gingivitis, and after 2 weeks of recovery. Means were compared using repeated measures ANOVA. Results Endotoxemia was reported in 56% of the serum samples at three weeks of induced gingivitis. At two weeks of recovery, endotoxin levels decreased to levels similar to those reported at baseline. Neutrophil oxidative activity increased significantly following three weeks of gingivitis versus baseline (pgingivitis was associated with endotoxemia and hyperactivity of circulating neutrophils, but not with changes in systemic levels of cytokines and acute phase proteins. This may be attributed to the mild nature and the short duration of the induced gingivitis. PMID:21320151

  7. White-spot Lesions and Gingivitis Microbiotas in Orthodontic Patients

    Science.gov (United States)

    Tanner, A.C.R.; Sonis, A.L.; Lif Holgerson, P.; Starr, J.R.; Nunez, Y.; Kressirer, C.A.; Paster, B.J.; Johansson, I.

    2012-01-01

    White-spot lesions (WSL) associated with orthodontic appliances are a cosmetic problem and increase risk for cavities. We characterized the microbiota of WSL, accounting for confounding due to gingivitis. Participants were 60 children with fixed appliances, aged between 10 and 19 yrs, half with WSL. Plaque samples were assayed by a 16S rRNA-based microarray (HOMIM) and by PCR. Mean gingival index was positively associated with WSL (p = 0.018). Taxa associated with WSL by microarray included Granulicatella elegans (p = 0.01), Veillonellaceae sp. HOT 155 (p gingivitis by microarray included: Gemella sanguinis (p = 0.002), Actinomyces sp. HOT 448 (p = 0.003), Prevotella cluster IV (p = 0.021), and Streptococcus sp. HOT 071/070 (p = 0.023); and levels of S. mutans (p = 0.02) and Bifidobacteriaceae (p = 0.012) by qPCR. Species’ associations with WSL were minimally changed with adjustment for gingivitis level. Partial least-squares discriminant analysis yielded good discrimination between children with and those without WSL. Granulicatella, Veillonellaceae and Bifidobacteriaceae, in addition to S. mutans and S. wiggsiae, were associated with the presence of WSL in adolescents undergoing orthodontic treatment. Many taxa showed a stronger association with gingivitis than with WSL. PMID:22837552

  8. Report a possible correlation between necrotizing ulcerative gingivitis and mononucleosis

    Directory of Open Access Journals (Sweden)

    Rosa Francinne Miranda

    2011-12-01

    Full Text Available Necrotizing ulcerative gingivitis is a relatively uncommon periodontal disease, characterized by ulceration, necrosis, pain and gingival bleeding. Factors often related to its occurrence include stress and systemic viral infections, such as those caused by cytomegalovirus and Epstein-Barr virus type 1, the latter being also considered the causative agent of infectious mononucleosis. This article aims to describe a clinical case of a female patient who presented with necrotizing ulcerative gingivitis associated with a clinical picture of infectious mononucleosis, as well as to review the literature concerning a possible correlation between these pathologies. This patient presented to our health care facility with necrotizing ulcerative gingivitis accompanied by lymphadenopathy, fever and prostration, after laboratory tests, Epstein-Barr virus type 1 infection was confirmed, as well as the co-occurrence of pathologies: necrotizing ulcerative gingivitis and infectious mononucleosis. Symptom remission in both disorders also occurred concomitantly, after instruction in plaque control measures and palliative medication for control of systemic symptoms. Therefore, although there is no scientific validation of an association between these two pathologies, it is imperative that all diagnostic alternatives be considered and investigated, in order to establish the therapeutic approach most appropriate to the patient.

  9. Simplificando el tratamiento quirúrgico de la sonrisa gingival Simplifying the surgical treatment of the gummy smile

    Directory of Open Access Journals (Sweden)

    H. Chacón Martínez

    2011-03-01

    Full Text Available La sonrisa es una de las expresiones más comunes del ser humano como muestra de satisfacción, alegría o felicidad. Algunas personas al sonreír muestran la encía por encima de la base de los dientes, lo que ocasiona un aspecto antiestético. Esta situación repercute negativamente en el individuo, ya que altera la espontaneidad de la expresión facial. En el origen de la sonrisa gingival intervienen factores dentales, esqueléticos y de tejidos blandos. Proponemos una variante quirúrgica innovadora para corregir la sonrisa gingival en pacientes con alteraciones de los tejidos blandos. Se intervinieron quirúrgicamente 15 mujeres de entre 17 y 38 años de edad. En 7 de ellas se practicó rinoplastia además de corrección de la sonrisa gingival. Las 8 restantes se sometieron exclusivamente a corrección de la sonrisa gingival. Las 15 pacientes intervenidas mejoraron su apariencia y autoestima. No hubo complicaciones o problemas relacionados con la herida quirúrgica. Los resultados han sido permanentes a medio y largo plazo. La sonrisa de las pacientes es normal, mejoró su expresión y se conservaron la sensibilidad y la función muscular. La técnica propuesta es sencilla y de fácil reproducción; el tiempo quirúrgico estimado es de una hora y la operación es de tipo ambulatoria. Suele ser bien tolerada por los pacientes y no altera sus actividades cotidianas.Human beings possess a highly expressive face, there are people who when smile, show the gums above the base of the teeth causing an antiesthetic aspect. This situation has negative repercussions altering the spontaneity of the facial expression. In the etiology of the gingival smile, dental, skeletal and soft tissue factors take part. We present a new surgical variant that offers an excellent alternative for the treatment of the gingival smile with soft tissue alterations. Fifteen female patients were treated; 7 had rhinoplasty together with correction of gingival smile; the

  10. Upregulation of lysyl oxidase expression in cyclosporin A-induced gingival overgrowth

    Directory of Open Access Journals (Sweden)

    Chung-Hung Tsai

    2009-03-01

    Conclusion: LOX expression was significantly upregulated in CsA-induced gingival overgrowth specimens. In addition, the expression of LOX increased with the grade of inflammation in CsA-induced gingival overgrowth.

  11. Hereditary gingival fibromatosis and growth retardation.

    Science.gov (United States)

    Bhowmick, S K; Gidvani, V K; Rettig, K R

    2001-01-01

    To describe two patients with hereditary gingival fibromatosis (HGF) and growth hormone deficiency and to review the literature on HGF and related endocrine abnormalities. We present case reports of two patients (first cousins)-an 8-year-old girl and a 13-year-old boy-with an existing diagnosis of HGF, who were assessed because of presumed growth failure. Both patients underwent growth hormone stimulation testing and more in-depth endocrine evaluation, including measurement of morning cortisol, adrenocorticotropic hormone (ACTH), and prolactin levels as well as thyroid function tests. An ACTH stimulation test was also performed. Radiologic evaluation included assessment of bone age and magnetic resonance imaging of the brain. In addition to HGF, both patients had short stature, subnormal growth velocity, and delayed bone age but no abnormalities on magnetic resonance imaging of the brain. Serum prolactin levels and results of thyroid function tests were normal. Subnormal growth hormone response was noted during hypoglycemia and pharmacologic stimuli with clonidine and levodopa. The female patient, who also had recurrent hypoglycemic episodes, had a suboptimal cortisol and ACTH response during hypoglycemia. On the ACTH stimulation test, she showed an inadequate cortisol response at 30 minutes but a normal response at 60 minutes. The male patient had normal morning cortisol and ACTH levels plus a normal response to ACTH stimulation. Both patients are responding well to treatment with growth hormone. The girl is also receiving cortisol replacement and has had no further episodes of hypoglycemia. Although HGF has been described as an isolated finding, it can occur as part of a syndrome, including infrequent endocrine abnormalities such as growth hormone insufficiency. The cause of the growth hormone deficiency remains unclear in these two patients. We believe that patients with HGF should be monitored carefully for a prolonged period for growth as well as other

  12. Prevalencia de helicobacter pylori en pacientes con gingivitis y enfermedad peridontal

    OpenAIRE

    Moroni Nakata, Hilda; Profesor Asociado D.E. Instituto de Investigación Estomatológica F.O - UNMSM.; Calle Espinoza, Sonia; Profesor Asociado D.E. Laboratorio de Microbiología - Fac. de Medicina Veterinaria - UNMSM.; Zambrano de la Pena, Sonia; Profesor Asociado TP Departamento Académico de Estomatología. Médico Quirúrgico-Periodoncia - Facultad de Odontología UNMSM.

    2014-01-01

    With the objetive of detennine the helicobacter pylori (Hp) prevsalencv in patiens with gingivitis and periodontal disease, it was collected and processed sullgingival plate samples from 177 patients whose have been classffied according to: 1) Ulcer and gingivitis, 2) gastritis and gingivitis, 3) gingivitis and 4) periodontitis aleatoriamente selected at the Odontological Clinic! of San Marcos University It was recovered Hp in 9,4%ftom the studied poblation, tnoreftecuenilly in women (6,8%) t...

  13. Protein carbonyl: An oxidative stress marker in gingival crevicular fluid in healthy, gingivitis, and chronic periodontitis subjects

    Directory of Open Access Journals (Sweden)

    Avani R Pradeep

    2013-01-01

    Full Text Available Background: A defined role for reactive oxygen species (ROS in the tissue destruction that characterizes periodontitis has been described. Protein carbonyl (PC is the most widely used biomarker for oxidative damage to proteins, and reflects cellular damage induced by multiple forms of ROS. The purpose of this study is to determine the presence of PC in gingival crevicular fluid (GCF in healthy, gingivitis, and chronic periodontitis (CP subjects and to find an association, if any. Materials and Methods: A total number of 75 subjects (38 males and 37 females were selected based on their clinical parameters into three groups: Group 1 (25 healthy subjects, Group 2 (25 gingivitis subjects, and Group 3 (25 CP subjects. GCF samples were collected to estimate the levels of PC. Results: The PC concentration in GCF was highest in subjects with CP as compared to gingivitis and healthy subjects and a significant association was observed between GCF PC levels and all periodontal parameters. Conclusion: There was an increase in PC levels in GCF as the disease process progressed from healthy to gingivitis and CP, suggesting a role for increased oxidative stress in CP.

  14. [Pigmentation and pigmented lesions of the gingival mucosa].

    Science.gov (United States)

    Mobio, S; Noujeim, Z; Boutigny, H; Jensen, M; Cassia, A; Soueidan, A

    2008-01-01

    The pigmentation is the physiological or pathological accumulation of a pigment in a tissue. Physiological pigmentation in gingiva which is a part of masticatory mucous membranes depends on the activity of the melanocytes. These non keratinocytic cells include the melanosoma where an endogenous pigment, the melanin, is synthesized. Quantitative or qualitative disruption of mucous pigmentation leads to the apparition of pigmented lesions. When melanocytes are directly concerned, the lesions can be of intrinsic origin, such as oral mucosa melanoma, the nevus, pigmented oral lichen planus etc. Pigmented lesions can be also of extrinsic origin caused by medicaments, dental materials, tobacco etc. In this article, gingival pigmentations are described to allow practitioner to elaborate a differential and positive diagnosis of gingival pigmented lesions and to facilitate an early detection of these lesions particularly the gingival melanoma.

  15. Management of Gingival Hyperpigmentation by Semiconductor Diode Laser

    Science.gov (United States)

    Gupta, Geeti

    2011-01-01

    Gingival hyperpigmentation is caused by excessive deposition of melanin in the basal and suprabasal cell layers of the epithelium. Although melanin pigmentation of the gingiva is completely benign, cosmetic concerns are common, particularly in patients having a very high smile line (gummy smile). Various depigmentation techniques have been employed, such as scalpel surgery, gingivectomy, gingivectomy with free gingival autografting, cryosurgery, electrosurgery, chemical agents such as 90% phenol and 95% alcohol, abrasion with diamond burs, Nd:YAG laser, semiconductor diode laser, and CO2 laser. The present case report describes simple and effective depigmentation technique using semiconductor diode laser surgery – for gingival depigmentation, which have produced good results with patient satisfaction. PMID:22279390

  16. Werewolf syndrome associated with gingival fibromatosis: A rare case report

    Directory of Open Access Journals (Sweden)

    Mysore K Sunil

    2016-01-01

    Full Text Available Hypertrichosis is a rare disorder that causes abnormal excessive body hair growth. Hypertrichosis has informally been called werewolf syndrome because the appearance is similar to that of a werewolf. It is often associated with additional anomalies including gingival hyperplasia, deafness, cardiomegaly and bone abnormalities. The association of gingival fibromatosis and a coarse facies could further worsen the esthetics. Thus, a multidisciplinary approach involving a psychologist, a dentist as well as a dermatologist would be mandatory. We present this rare syndrome describing a case of a 9-year-old boy with congenital hypertrichosis and gingival fibromatosis. The growth being normal, the features of this boy were similar to hypertrichosis. Hypertrichosis has informally been called werewolf syndrome because the appearance is similar to the werewolf.

  17. Plasma cell gingivitis associated with cheilitis: A diagnostic dilemma!

    Directory of Open Access Journals (Sweden)

    Presanthila Janam

    2012-01-01

    Full Text Available Plasma cell gingivitis is a rare condition characterized by diffuse and massive infiltration of plasma cells into the sub-epithelial connective tissue. Clinically, it appears as a diffuse reddening and edematous swelling of the gingiva with a sharp demarcation along the mucogingival border. Though considered as a hypersensitive reaction to an allergen, the etiology of this bizarre condition is still not properly understood. Here, we present an interesting case of plasma cell gingivitis associated with an enlarged and fissured upper lip, which is quite a rarity. The condition was diagnosed based on clinical and histopathologic findings and treated by gingivectomy. The associated cheilitis has dramatically reduced after treatment of the gingival lesion.

  18. Management of gingival hyperpigmentation by semiconductor diode laser

    Directory of Open Access Journals (Sweden)

    Geeti Gupta

    2011-01-01

    Full Text Available Gingival hyperpigmentation is caused by excessive deposition of melanin in the basal and suprabasal cell layers of the epithelium. Although melanin pigmentation of the gingiva is completely benign, cosmetic concerns are common, particularly in patients having a very high smile line (gummy smile. Various depigmentation techniques have been employed, such as scalpel surgery, gingivectomy, gingivectomy with free gingival autografting, cryosurgery, electrosurgery, chemical agents such as 90% phenol and 95% alcohol, abrasion with diamond burs, Nd:YAG laser, semiconductor diode laser, and CO 2 laser. The present case report describes simple and effective depigmentation technique using semiconductor diode laser surgery - for gingival depigmentation, which have produced good results with patient satisfaction.

  19. Human Gingival Crevicular Fluids (GCF Proteomics: An Overview

    Directory of Open Access Journals (Sweden)

    Zohaib Khurshid

    2017-02-01

    Full Text Available Like other fluids of the human body, a gingival crevicular fluid (GCF contains proteins, a diverse population of cells, desquamated epithelial cells, and bacteria from adjacent plaque. Proteomic tools have revolutionized the characterization of proteins and peptides and the detection of early disease changes in the human body. Gingival crevicular fluids (GCFs are a very specific oral cavity fluid that represents periodontal health. Due to their non-invasive sampling, they have attracted proteome research and are used as diagnostic fluids for periodontal diseases and drug analysis. The aim of this review is to explore the proteomic science of gingival crevicular fluids (GCFs, their physiology, and their role in disease detection.

  20. Histological and immunohistochemical features of gingival enlargement in a patient with AML

    NARCIS (Netherlands)

    Sonoi, Norihiro; Soga, Yoshihiko; Maeda, Hiroshi; Ichimura, Koichi; Yoshino, Tadashi; Aoyama, Kazutoshi; Fujii, Nobuharu; Maeda, Yoshinobu; Tanimoto, Mitsune; Logan, Richard; Raber-Durlacher, Judith; Takashiba, Shogo

    2012-01-01

    Here, we discuss the pathophysiology of leukemia-associated gingival enlargement based on a case of acute myelomonocytic leukemia (AML-M4) with typical gingival enlargement. Uniquely, this patient was well enough to allow full periodontal examination and incisional gingival biopsy to be performed

  1. The impacts of gingivitis and calculus on Thai children's quality of life.

    Science.gov (United States)

    Krisdapong, Sudaduang; Prasertsom, Piyada; Rattanarangsima, Khanit; Sheiham, Aubrey; Tsakos, Georgios

    2012-09-01

    To assess associations of socio-demographic, behavioural and the extent of gingivitis and calculus with oral health-related quality of life (OHRQoL) in nationally representative samples of 12- and 15-year-old Thai children. In the Thailand National Oral Health Survey, 1,063 twelve-year olds and 811 fifteen-year olds were clinically examined and interviewed for OHRQoL using the Child-OIDP and OIDP indices, respectively, and completed a behavioural questionnaire. We assessed associations of condition-specific impacts (CS-impacts) with gingivitis and calculus, adjusted for socio-demographic and behavioural factors. Gingivitis and calculus were highly prevalent: 79.3% in 12-year and 81.5% in 15-year olds. CS-impacts relating to calculus and/or gingivitis were reported by 26.0% of 12-year and 29.6% of 15-year olds. Except for calculus without gingivitis, calculus and/or gingivitis in any form was significantly related to any level of CS-impacts. At a moderate or higher level of CS-impacts, there were significant relationships with extensive calculus and/or gingivitis in 12-year olds and for extensive gingivitis and gingivitis without calculus in 15-year olds. Gingivitis was generally associated with any level of CS-impacts attributed to calculus and/or gingivitis. CS-impacts were related more to gingivitis than to calculus. © 2012 John Wiley & Sons A/S.

  2. Presence of gingivitis and periodontitis significantly increases hospital charges in patients undergoing heart valve surgery.

    Science.gov (United States)

    Allareddy, Veerasathpurush; Elangovan, Satheesh; Rampa, Sankeerth; Shin, Kyungsup; Nalliah, Romesh P; Allareddy, Veerajalandhar

    2015-01-01

    To examine the prevalence and impact of gingivitis and periodontitis in patients having heart valve surgical procedures. Nationwide Inpatient Sample for the years 2004-2010 was used. All patients who had heart valve surgical procedures were selected. Prevalence of gingivitis/periodontitis was examined in these patients. Impact of gingivitis/periodontitis on hospital charges, length of stay, and infectious complications was examined. 596,190 patients had heart valve surgical procedures. Gingivitis/periodontitis was present in 0.2 percent. Outcomes included: median hospital charges ($175,418 with gingivitis/ periodontitis versus $149,353 without gingivitis/periodontitis) and median length of stay (14 days with gingivitis/periodontitis versus 8 days without gingivitis/periodontitis). After adjusting for the effects of patient- and hospital-level confounding factors, hospital charges and length of stay were significantly higher (p gingivitis/periodontitis compared to their counterparts. Further, patients with gingivitis/periodontitis had significantly higher odds for having bacterial infections (OR = 3.41, 95% CI = 2.33-4.98, p gingivitis/periodontitis. Presence of gingivitis and periodontitis is associated with higher risk for bacterial infections and significant hospital resource utilization.

  3. Binding, uptake, and release of nicotine by human gingival fibroblasts

    Energy Technology Data Exchange (ETDEWEB)

    Hanes, P.J.; Schuster, G.S.; Lubas, S. (Medical College of Georgia, Augusta (USA))

    1991-02-01

    Previous studies of the effects of nicotine on fibroblasts have reported an altered morphology and attachment of fibroblasts to substrates and disturbances in protein synthesis and secretion. This altered functional and attachment response may be associated with changes in the cell membrane resulting from binding of the nicotine, or to disturbances in cell metabolism as a result of high intracellular levels of nicotine. The purpose of the present study, therefore, was to (1) determine whether gingival fibroblasts bound nicotine and if any binding observed was specific or non-specific in nature; (2) determine whether gingival fibroblasts internalized nicotine, and if so, at what rate; (3) determine whether gingival fibroblasts also released nicotine back into the extracellular environment; and (4) if gingival fibroblasts release nicotine intact or as a metabolite. Cultures of gingival fibroblasts were prepared from gingival connective tissue biopsies. Binding was evaluated at 4{degree}C using a mixture of {sup 3}H-nicotine and unlabeled nicotine. Specific binding was calculated as the difference between {sup 3}H-nicotine bound in the presence and absence of unlabeled nicotine. The cells bound 1.44 (+/- 0.42) pmols/10(6) cells in the presence of unlabeled nicotine and 1.66 (+/- 0.55) pmols/10(6) cells in the absence of unlabeled nicotine. The difference was not significant. Uptake of nicotine was measured at 37{degree}C after treating cells with {sup 3}H-nicotine for time periods up to 4 hours. Uptake in pmols/10(6) cells was 4.90 (+/- 0.34) at 15 minutes, 8.30 (+/- 0.75) at 30 minutes, 12.28 (+/- 2.62) at 1 hour and 26.31 (+/- 1.15) at 4 hours.

  4. The gingival biotype assessed by experienced and inexperienced clinicians.

    Science.gov (United States)

    Eghbali, Aryan; De Rouck, Tim; De Bruyn, Hugo; Cosyn, Jan

    2009-11-01

    A recent cluster analysis has identified three gingival biotypes among 100 periodontally healthy subjects based on different combinations of morphometric data related to maxillary front teeth and surrounding soft tissues. Patients with a thin-scalloped biotype are considered at risk because they have been associated with a compromised soft tissue response following surgical and/or restorative therapy. Hence, an accurate identification of these high-risk patients is warranted. The purpose of the present study was to evaluate the precision of simple visual inspection as a method to identify the gingival biotype by experienced and inexperienced clinicians. Fifteen clinicians (five Restorative Dentists, five Periodontists and five Students) were invited to assess the gingival biotype (thin-scalloped, thick-flat, thick-scalloped) of 100 periodontally healthy subjects based on clinical slides. Cluster analysis on these subjects was used as the gold standard and the accuracy in identifying the gingival biotype was determined using percentile agreement and kappa statistics. Intra- and inter-examiner reliability were also calculated. The gingival biotype was accurately identified only in about half of the cases irrespective of the clinician's experience. The thick-flat biotype was mostly recognized especially by experienced clinicians (> or =70% of the cases). Nearly half of the thin-scalloped cases were misclassified. The intra-examiner repeatability was fair to substantial (kappa: 0.328-0.670) and the inter-examiner reproducibility was slight to moderate (kappa: 0.127-0.547). Simple visual inspection may not be considered a valuable method to identify the gingival biotype as nearly half of the high-risk patients are overlooked.

  5. Chronic gingivitis and aphthous stomatitis relationship hypothesis: A neuroimmunobiological approach

    Directory of Open Access Journals (Sweden)

    Chiquita Prahasanti

    2009-03-01

    Full Text Available Background: Traumatic injuries to the oral mucosa in fixed orthodontic patients are common, especially in the first week of bracket placement, and occasionally lead to the development of aphthous stomatitis or ulcers. Nevertheless, these lesions are selflimiting. Purpose: The objective of this study is to reveal the connection between chronic gingivitis and aphthous stomatitis which is still unclear. Case: A patient with a persistent lesion for more than six months. Case Management: RAS was treated with scaling procedure, the gingival inflammation was healed. However, in this case report, despite the appropriate management procedures had been done, the lesion still worsen and became more painful. Moreover, the symptoms did not heal for more than two weeks. Actually, they had been undergone orthodontic treatment more than six months and rarely suffered from aphthous stomatitis. Coincidentally, at that time they also suffered from chronic gingivitis. It was interesting that after scaling procedures, the ulcer subsides in two days. Conclusion: Recently, the neuroimmunobiological researches which involved neurotransmitters and cytokines on cell-nerve signaling, and heat shock proteins in gingivitis and stomatitis are in progress. Nevertheless, they were done separately, thus do not explain the interrelationship. This proposed new concept which based on an integrated neuroimmunobiological approach could explain the benefit of periodontal treatment, especially scaling procedures, for avoiding prolonged painful episodes and unnecessary medications in aphthous stomatitis. However, for widely acceptance of the chronic gingivitis and aphthous stomatitis relationship, further clinical and laboratory study should be done. Regarding to the relatively fast healing after scaling procedures in this case report; it was concluded that the connection between chronic gingivitis and aphthous stomatitis is possible.

  6. Experimental gingivitis around deciduous teeth in children with Down's syndrome.

    Science.gov (United States)

    Reuland-Bosma, W; van Dijk, J; van der Weele, L

    1986-04-01

    Epidemiological studies have shown that there is a high prevalence and rapid progression of periodontal disease in children with Down's Syndrome (DS). In this respect, DS children exhibit a markedly different response compared with healthy children. In order to understand the reasons for this difference, a controlled study was set up to determine the extent and the quality of the differences in the early periodontal tissue response towards dental plaque in the deciduous dentition of DS children and matched control children. In a preliminary investigation, the gingival health was estimated by determining the bleeding tendency. 9 healthy children were selected from a group of 14 and matched with 9 DS children with respect to plaque development, sulcus depth and age. The DS children had a higher bleeding tendency than the matched controls. In the DS children, moreover, a correlation was found between bleeding tendency and age. No such correlation was found in the controls. After a period of intensive oral hygiene, all cleaning of teeth was discontinued for 21 days. The amount of plaque according to the plaque index, the gingival health according to the gingival index, and the amount of crevicular leucocytes and gingival exudate were assessed at days 0, 7, 14 and 21. During the experimental phase of the study, the amount of plaque increased at a similar rate in both groups. In the DS children, the development of gingival inflammation started earlier and was more extensive. It increased after day 14, whereas in the control children, the gingival inflammation seemed to stabilize at this time. The results of the present experimental study thus confirm earlier results from epidemiological studies.(ABSTRACT TRUNCATED AT 250 WORDS)

  7. Gingival recession--can orthodontics be a cure?

    Science.gov (United States)

    Northway, William M

    2013-11-01

    Does orthodontic treatment help or hinder a patient's periodontal status? What factors affect the periodontium? Can those factors be managed in a way that remedies existing periodontal issues? A 35-year-old woman presented with severe gingival recession and a unilateral Class II malocclusion. The treatment plan was to correct the malocclusion in a way that torques the roots more onto bone and to change her dental hygiene methods. With an extensive review of the literature, this case review attempts to make sense of the enigma of gingival recession and demonstrates an excellent treatment solution to concomitant orthodontic and periodontal problems.

  8. Kaitan Antara Status Gizi dengan Gingivitis di Kecamatan Karangantu Banten

    Directory of Open Access Journals (Sweden)

    Nurlaila Abdullah Mashabi

    2015-09-01

    Full Text Available Studies in Indonesia which attempt to correlate nutritional status with dental health are still needed. The aim of this study was to find out the effect of nutritional status on dental health particularly gingivitis of the school children aged 9 – 14 years in Karangantu and Pamarican II Elementary schools. Nutrition status was assessed using limited antropometry, height and weight measurements. Cross sectional methods she used, and the result young data ANOVA, T-Test and Chi-Square. The results of the study showed were analyzed no correlation between nutritional status and gingivitis.

  9. Desquamative gingivitis: what's behind it? A case report.

    Science.gov (United States)

    Parwani, Simran R; Parwani, Rajkumar N

    2014-01-01

    Desquamative gingivitis (DG) is a clinical term used to describe red, painful, glazed, friable gingiva. It may be a manifestation of a mucocutaneous condition, such as lichen planus or other vesiculobulous disorders. Dentists must be aware of this rare clinical entity in order to distinguish DG from the far more common plaque-induced gingivitis. This case is unique in that it involves oral lichen planus and chronic DG, which may be secondary to plaque or a manifestation of the oral lichen planus. Intraoral examination and biopsy reports revealed features of chronic DG and oral reticular lichen planus.

  10. Gingivitis en escolares de ambos sexos, pertenecientes a la escuela fiscal mixta Inés Gangotena Jijón, cantón Rumiñahui – Sangolquí, Octubre – Diciembre del 2013

    OpenAIRE

    Carrera Oscullo, Wilson Alberto

    2014-01-01

    La gingivitis en escolares es una enfermedad de origen multifactorial, siendo las primeras causas: la mala técnica de cepillado, falta de cepillado, mala oclusión, o respiración bucal. El presente trabajo de investigación tiene como objetivos el determinar la prevalencia y el grado de gingivitis que presentan los niños de la Escuela Inés Gangotena Jijón de Sangolquí, cantón Rumiñahui. La población en estudio que participó en el proyecto estuvo formada por 208 estudiantes del plantel, a quien...

  11. Despigmentación gingival y cirugía de alargamiento coronal en erupción pasiva alterada tipo IA e IB en el mismo tiempo quirúrgico / Gingival Depigmentation and Crown Lengthening in IA- and IB-Type Altered Passive Eruption in the same Surgical Procedure

    OpenAIRE

    Molano Valencia, Pablo Emilio; Universidad del Valle; Quisoboni Eguizábal, Jorge Fernando; Universidad del Valle; Yepes Ramírez, Bibiana Inés; Universidad del Valle

    2015-01-01

    Antecedentes: La pigmentación gingival es una característica racial en la cual el melanocito produce el pigmento desde su localización en la capa basal del epitelio oral. La erupción pasiva alterada es una anomalía de la erupción dental en la cual la encía o el hueso no migran apicalmente, por lo que los dientes quedan cortos y cuadrados. Asimismo, histológicamente puede haber una cresta ósea alta. Por lo regular, los pacientes que tienen erupción pasiva alterada y pigmentación gingival melán...

  12. Association between maternal gingivitis, low birth weight and ...

    African Journals Online (AJOL)

    Objective: To determine the association between maternal gingivitis and pregnancy outcome, including low birth weight (LBW) and preterm delivery. This prospective study was conducted among 300 randomly selected pregnant women aged 20-34 years attending the antenatal clinic, University of Benin Teaching Hospital, ...

  13. Potential Immune Modularly Role of Glycine in Oral Gingival Inflammation

    Directory of Open Access Journals (Sweden)

    Teresa Schaumann

    2013-01-01

    Full Text Available Gingival epithelial cells (GECs represent a physical barrier against bacteria and are involved in the processes of innate immunity. Recently, an anti-inflammatory and immune-modulatory effect of the amino acid glycine has been demonstrated. However, there is only little information about the immune-modulatory effects of glycine in oral tissues. This study aimed to investigate the existence and role of the glycine receptor in gingival tissue analyzing tissues/cells from extracted human molars via immunohistochemical analysis. In vitro, GECs were challenged by inflammatory conditions with IL-1β alone or in combination with glycine and analyzed for cytokine expression of IL6/IL8 via real-time PCR. On protein level, the effect of nuclear translocalization of NFκB protein p65 was analyzed using immunofluorescence analysis. A distinct proof of the GlyR in oral gingival tissue and keratinocytes could be demonstrated. Isolated challenge of the keratinocytes with IL-1β as well as with glycine resulted in an upregulation of IL6 and IL8 mRNA expression and activation of NFκB pathway. The presence of glycine in combination with the inflammatory stimulus led to a significant decrease in inflammatory parameters. These results indicate a possible anti-inflammatory role of glycine in gingival inflammation and encourage further research on the utility of glycine in the prevention or therapy of inflammatory periodontitis.

  14. Orthodontic therapy and gingival recession: a systematic review.

    NARCIS (Netherlands)

    Joss-Vassalli, I.; Grebenstein, C.; Topouzelis, N.; Sculean, A.; Katsaros, C.

    2010-01-01

    To perform a systematic review on the effect of changes in incisor inclination owing to orthodontic treatment and the occurrence of gingival recession. PubMed, EMBASE Excerpta Medica and CENTRAL of the Cochrane Library were searched and a hand search was performed. From 1925 articles identified, 17

  15. Effect of phenytoin and age on gingival fibroblast enzymes.

    Directory of Open Access Journals (Sweden)

    Surena Vahabi

    2014-06-01

    Full Text Available The alteration of cytokine balance is stated to exert greater influence on gingival overgrowth compared to the direct effect of the drug on the regulation of extracellular matrix metabolism. The current study evaluated the effect of phenytoin on the regulation of collagen, lysyl oxidase and elastin in gingival fibroblasts.Normal human gingival fibroblasts (HGFs were obtained from 4 healthy children and 4 adults. Samples were cultured with phenytoin. MTT test was used to evaluate the proliferation and ELISA was performed to determine the level of IL1β and PGE2 production by HGFs. Total RNA of gingival fibroblasts was extracted and RT-PCR was performed on samples. Mann-Whitney U test was used to analyze the data with an alpha error level less than 0.05.There was a significant difference in the expression of elastin between the controls and treated samples in both adult and pediatric groups and also in the lysyl oxidase expression of adult controls and treated adults. No significant difference was found between collagen expression in adults.The significant difference in elastin and lysyl oxidase expression between adult and pediatric samples indicates the significant effect of age on their production.

  16. Acute Leukemia Presenting with Gingival Bleeding. A Case Report ...

    African Journals Online (AJOL)

    This is a case report of a five year-old girl with acute lymphoblastic leukaemia who presented in our clinic with gingival bleeding. Sepcific highlights were focused on the management of the patient and current trends in the treatment of the disease with emphasis on early diagnosis of the disease in other to improve the ...

  17. No association between gingival labial recession and facial type

    NARCIS (Netherlands)

    Mazurova, K.; Renkema, A.M.; Navratilova, Z.; Katsaros, C.; Fudalej, P.S.

    2016-01-01

    OBJECTIVE: To evaluate if facial type is a predictor of the development of gingival recession. METHODS: A cohort of 179 orthodontic patients (76 males, 101 females; age before treatment T S = 12.4 years, SD = 0.8) were followed until 5 years post-treatment (T 5 = 20.7 years, SD = 1.2). The presence

  18. Report of hereditary gingival fibromatosis in two Nigerian siblings ...

    African Journals Online (AJOL)

    Background: Hereditary Gingival Fibromatosis (HGF) is a rare condition with a prevalence of 1:750,000, and can present as an isolated disorder or more rarely as a syndrome component. It is characterised by a slow and progressive enlargement of both maxillary and mandibular 28rganiza with varying severity between ...

  19. Esthetic Management of Gingival Lesions in Anterior Maxilla: The ...

    African Journals Online (AJOL)

    Figure 5: Decision tree for esthetic management of gingival lesion in anterior maxilla. Figure 3: (a) VIP‑CT flap from the palate. (b) Supraperiosteal sharp dissection in labial region (pouch technique). (c) The flap was stabilized with 5‑0 non resorbable sutures. (d) Healthy and esthetic gingiva four weeks after operation d c b a.

  20. Prevention of gingival trauma : Oral hygiene devices and oral piercings

    NARCIS (Netherlands)

    Hoenderdos, N.L.

    2017-01-01

    Maintaining healthy teeth and soft oral tissues for life is important. Oral hygiene devices and oral piercings can damage the soft oral tissues. This thesis investigates the safety of manual toothbrushes, interdental brushes and rubber bristles interdental cleaners by analysing the gingival abrasion

  1. Smad2 decelerates re-epithelialization during gingival wound healing.

    Science.gov (United States)

    Tomikawa, K; Yamamoto, T; Shiomi, N; Shimoe, M; Hongo, S; Yamashiro, K; Yamaguchi, T; Maeda, H; Takashiba, S

    2012-08-01

    During periodontal regeneration, inhibition of gingival downgrowth is necessary to promote migration of mesenchymal cells into the defects. Transforming growth factor (TGF)-β is a pleiotropic cytokine that has numerous cell functions, including regulation of epithelial growth. Recent studies have shown that Smad2, a downstream transcription factor of TGF-β, plays crucial roles in wound healing in the epithelia. Therefore, we investigated the effects of Smad2 overexpression on re-epithelialization of gingival wounds. Transgenic mice overexpressing smad2 driven by the keratin 14 promoter (k14-smad2) were confirmed to have significant Smad2 phosphorylation in gingival basal epithelia. Punch wounds were made in the palatal gingiva, and wound healing was assessed histologically for 7 days. Re-epithelialization was significantly retarded on day 2, while collagen deposition was enhanced on day 7 in k14-smad2 compared with wild-type mice. Moreover, expression of keratin 16 (K16), an indicator of keratinocyte migration, was significantly inhibited in wound-edge keratinocytes in k14-smad2. The inhibition of K16 coincided with the induction of Smad2 in the corresponding epithelia, while BrdU incorporation was unaffected. These results indicated that Smad2 has inhibitory effects in regulating keratinocyte migration during gingival wound healing. TGF-β/Smad2 signaling mediating alteration of K16 expression must be tightly regulated during periodontal regeneration.

  2. The effect of two toothpastes on plaque and gingival inflamation.

    Science.gov (United States)

    Saxer, U P; Menghini, G; Bohnert, K J; Ley, F

    1995-01-01

    In this study on 60 adult subjects, the effective of Parodontax, a dentifrice containing herbal ingredients and sodium bicarbonate abrasive, was compared to a non-marketed new toothpaste containing herbal ingredients and calcium hydrogen phosphate as the abrasive. Plaque, gingivitis and gingival bleeding parameters were scored. The periodontal probe bleeding index of Ainamo and Bay was modified to score slight and moderate bleeding. In this first four-week period all subjects used the new toothpaste. After this period the new toothpaste produced a significant decrease (p<0.01) in gingivitis and bleeding on probing, but no effect on plaque was observed. During the second period of eight weeks the subjects were randomly divided into two groups, one using Parodontax and the other group continuing with the new toothpaste. The study design was a double-blind procedure. At the end of the 12-week study period the plaque index showed no changes in both groups. The gingivitis and bleeding indices decreased significantly (p<0.001) by 40% in both groups compared to the baseline examination.

  3. Gingival fibromatosis with hypertrichosis syndrome: Case series of rare syndrome

    Directory of Open Access Journals (Sweden)

    Preetha Balaji

    2017-01-01

    Full Text Available Gingival fibromatosis with hypertrichosis syndrome is an extremely rare genetic condition characterized by profound overgrowth of hair and gums, as well as other variable features. Gingival fibromatosis is characterized by a large increase in the gingival dimension which extends above the dental crowns, covering them partially or completely. They were found to have a genetic origin, may also occur in isolation or be part of a syndrome, or acquired origin, due to specific drugs administered systemically. Congenital generalized hypertrichosis is a heterogeneous group of diseases with continuing excessive growth of terminal hair without androgenic stimulation. It has informally been called werewolf syndrome because the appearance is similar to that of a werewolf. Various syndromes have been associated with these features such as epilepsy, mental retardation, cardiomegaly, or osteochondrodysplasia. As so far very few cases have been reported in literature, we are reporting a series of three cases with management of the same. The excess gingival tissues, in these cases, were removed by conventional gingivectomy under general anesthesia. The postoperative result was uneventful and the patient's appearance improved significantly. Good esthetic result was achieved to allow patient to practice oral hygiene measures. Though this is not a serious condition clinically, psychosocial trauma cannot be neglected owing to the cosmetic disfigurement it produces.

  4. In vitro assessment of cytotoxicity of giomer on human gingival ...

    African Journals Online (AJOL)

    Discs (6×2 mm) of GC and RI restorative materials were prepared using sterile Teflon mold. Extracts from the materials were incubated to cell culture medium for 24, 48 and 72 h. Human gingival fibroblasts (HGF) were exposed to the extracts of the materials while the unincubated media served as the control group.

  5. The surgical treatment of the multiple gingival recessions

    OpenAIRE

    MAMPIERI, G.; ARULLANI, C.; CECCHETTI, F.

    2009-01-01

    The growing emphasis on aesthetics puts the dentist before new requests for intervention aimed at improving the smile not only in dental component but also in the gingival. Infact, even among patients is now widespread awareness that the beauty of the smile comes from balance existing, in the relations and proportions, between the dental and gum component.

  6. A longitudinal study of the prevalence of gingival bleeding among ...

    African Journals Online (AJOL)

    Objective: To assess the prevalence of gingival bleeding following gentle periodontal probing during pregnancy as compared to after child birth in the same set of women. Method: Three hundred and eighty-four consecutive pregnant women in third trimester were selected at the antenatal clinics of Adeoyo Maternity ...

  7. Gingival recession, oral hygiene and associated factors among ...

    African Journals Online (AJOL)

    Background: Females are generally more motivated with regard to oral hygiene practices and thus brush their teeth more frequently than males. Objective: To determine the prevalence of gingival recession, oral hygiene status, oral hygiene practices and associated factors in women attending a maternity ward in Tanzania.

  8. Local and Systemic Inflammatory Responses to Experimentally Induced Gingivitis

    Science.gov (United States)

    Leishman, Shaneen J.; Seymour, Gregory J.; Ford, Pauline J.

    2013-01-01

    This study profiled the local and systemic inflammatory responses to experimentally induced gingivitis. Eight females participated in a 21-day experimental gingivitis model followed by a 14-day resolution phase. Bleeding on probing and plaque index scores were assessed before, during, and after resolution of gingival inflammation, and samples of saliva, GCF, and plasma were collected. Samples were assessed for biomarkers of inflammation using the BioPlex platform and ELISA. There were no significant changes in GCF levels of cytokines during the experimental phase; however, individual variability in cytokine profiles was noted. During resolution, mean GCF levels of IL-2, IL-6, and TNF-α decreased and were significantly lower than baseline levels (P = 0.003, P = 0.025, and P = 0.007, resp.). Furthermore, changes in GCF levels of IL-2, IL-6, and TNF-α during resolution correlated with changes in plaque index scores (r = 0.88, P = 0.004; r = 0.72, P = 0.042; r = 0.79, P = 0.019, resp.). Plasma levels of sICAM-1 increased significantly during the experimental phase (P = 0.002) and remained elevated and significantly higher than baseline levels during resolution (P gingivitis adds to the systemic inflammatory burden of an individual. PMID:24227893

  9. Soft tissue engineering with micronized-gingival connective tissues.

    Science.gov (United States)

    Noda, Sawako; Sumita, Yoshinori; Ohba, Seigo; Yamamoto, Hideyuki; Asahina, Izumi

    2018-01-01

    The free gingival graft (FGG) and connective tissue graft (CTG) are currently considered to be the gold standards for keratinized gingival tissue reconstruction and augmentation. However, these procedures have some disadvantages in harvesting large grafts, such as donor-site morbidity as well as insufficient gingival width and thickness at the recipient site post-treatment. To solve these problems, we focused on an alternative strategy using micronized tissue transplantation (micro-graft). In this study, we first investigated whether transplantation of micronized gingival connective tissues (MGCTs) promotes skin wound healing. MGCTs (≤100 µm) were obtained by mincing a small piece (8 mm 3 ) of porcine keratinized gingiva using the RIGENERA system. The MGCTs were then transplanted to a full skin defect (5 mm in diameter) on the dorsal surface of immunodeficient mice after seeding to an atelocollagen matrix. Transplantations of atelocollagen matrixes with and without micronized dermis were employed as experimental controls. The results indicated that MGCTs markedly promote the vascularization and epithelialization of the defect area 14 days after transplantation compared to the experimental controls. After 21 days, complete wound closure with low contraction was obtained only in the MGCT grafts. Tracking analysis of transplanted MGCTs revealed that some mesenchymal cells derived from MGCTs can survive during healing and may function to assist in wound healing. We propose here that micro-grafting with MGCTs represents an alternative strategy for keratinized tissue reconstruction that is characterized by low morbidity and ready availability. © 2017 Wiley Periodicals, Inc.

  10. Gingival melanin de-pigmentation for aesthetic correction

    National Research Council Canada - National Science Library

    Chacko, Lisa Neelathil; Abraham, Sathish

    2014-01-01

    ... from light brown, dark brown to black. 1 Extensive gingival pigmentation can pose serious aesthetic concerns among the affected which may lead to low self-esteem and confidence. Patients and the general public have now become more aesthetically conscious. This may be attributed to continuing education about oral healthcare and its bene...

  11. Drug-induced gingival enlargement: Series of cases

    Directory of Open Access Journals (Sweden)

    Isabella Manzur-Villalobos

    2018-01-01

    Full Text Available Introduction: Gingival enlargement (GA is a benign condition of the oral cavity that is characterized by the excessive growth of the gingiva in mass and volume. This lesion is not only caused by hereditary factors or poor oral hygiene, but also by the intake of medications, including antihypertensive, anticonvulsant and immunosuppressive drugs. Objective: To sensitize the prevention or early care in patients with pathologies that merit the use of antihypertensive and anticonvulsants in conjunction with the dentist, to treat or avoid the drug-induced gingival enlargement (DIGE. Materials and methods: A series of clinical cases of patients with gingival enlargement by various drugs are reported, including Phenytoin, Amlodipine and Nifedipine. Periodontal and gingivectomy hygienic phase measures were applied to obtain better effects. Results: Satisfactory results were obtained with a considerable decrease in DIGE. Conclusions: The integral management is important in conjunction with the treating physician to follow up the drug that can be generating gingival enlargement. It is necessary to employ an initial approach with strategies of periodontal hygiene, and in severe cases and, as last resort, the periodontal surgery with gingivectomy and gingivoplasty.

  12. Efektifitas Propolis Toothpaste sebagai Initial Therapy pada Mild Gingivitis

    Directory of Open Access Journals (Sweden)

    Nila Kasuma

    2015-02-01

    Full Text Available Karakteristik gingivitis ringan adalah terjadinya perubahan warna gusi, edema ringan, tidak ada pendarahan dan tanpa ada rasa nyeri. Jika pasien tidak mendapatkan perawatan yang tepat, gingivitis dapat berubah menjadi periodontitis yang menyebabkan kerusakan jaringan tulang rahang alveolar, menyebabkan kerusakan jaringan lebih lanjut secara lokal dan sistemik melalui pembuluh darah. Pemilihan terapi yang tepat sangat penting untuk mengurangi prevalensi dari penyakit ini. Selain proses scaling dan kontrol plak, penggunaan pasta gigi propolis dapat digunakan sebagai terapi awal. Komposisi pasta gigi yang mengandung propolis memiliki efek anti-inflamasi yang bermanfaat sebagai salah satu terapi awal untuk mengobati gingivitis ringan. Penelitian ini menggunakan metode eksperimen. Indeks gingiva dari 15 pasien diukur sebelum dan sesudah penggunaan pasta gigi propolis. Analisis data dilakukan dengan cara univariat untuk menggambarkan masing-masing variabel dengan Kolmogorov-Smirnof Test. Perbedaan indeks gingiva antara sebelum dan sesudah menyikat gigi dengan pasta gigi yang mengandung propolis dianalisis dengan uji T berpasangan. Pasta gigi yang mengandung propolis ini terbukti efektif dalam terapi awal gingivitis ringan dengan rata-rata pengurangan skor indeks gingiva sebelum dan sesudah adalah 0,40 ± 0,04. Terdepat perbedaan yang signifikan (p <0,05 antara rata-rata penurunan nilai gingiva indeks sebelum dan setelah penggunaan pasta gigi yang mengandung propolis.

  13. The effect of different interdental cleaning devices on gingival bleeding

    NARCIS (Netherlands)

    Rosema, N.A.M.; Hennequin-Hoenderdos, N.L.; Berchier, C.E.; Slot, D.E.; Lyle, D.M.; van der Weijden, G.A.

    2011-01-01

    Objective: To compare the effectiveness of an oral irrigator (OI) with a prototype jet tip or a standard jet tip to floss as adjunct to daily toothbrushing on gingival bleeding. Methods: In this single masked, 3-group parallel, 4-week home use experiment, 108 subjects were randomly assigned to one

  14. Asociación del papilomavirus humano 13 con la hiperplasia epitelial focal de la población indígena Embera-Chamí de Jardín, Antioquia, Colombia

    Directory of Open Access Journals (Sweden)

    Sanclemente Gloria

    2005-12-01

    Full Text Available Se ha sugerido una etiología viral de la HEF (Hiperplasia epitelial focal, siendo el propósito de este trabajo de casos y controles confirmar la existencia de la asociación mediante la técnica de PCR. Se encontró que ésta existe y que la PCR es una técnica confiable para determinarla. Otras variables de tipo social, de conducta o infecciosas, evaluadas en el estudio, no mostraron
    asociación estadísticamente significativa. En el futuro será  necesaria la evaluación de características genéticas e inmunológicas de los casos y los controles para determinar otros factores de riesgo que interactúan de forma diferente en cada individuo e influyen en el desarrollo o no de la enfermedad.

  15. Sodium valproate induced gingival enlargement with pre-existing chronic periodontitis

    Directory of Open Access Journals (Sweden)

    Vaibhavi Joshipura

    2012-01-01

    Full Text Available Gingival enlargement is a common clinical feature of gingival and periodontal diseases. Currently, more than 20 prescription medications are associated with gingival enlargement. Although the mechanisms of action may be different, the clinical and microscopic appearance of drug-induced gingival enlargement is similar with any drug. Gingival enlargement produces esthetic changes, and clinical symptoms including pain, tenderness, bleeding, speech disturbances, abnormal tooth movement, dental occlusion problems, enhancement of caries development and periodontal disorders. Sodium valproate is considered to produce gingival enlargement, but very rarely. This case report features sodium valproate induced gingival enlargement in a patient with pre-existing chronic periodontitis, who came to the Dental Department, Chinmaya Mission Hospital, Bangalore. The case is special as the patient did not develop the enlargement in spite of taking phenytoin for 1 year and developed enlargement with sodium valproate within 6 months.

  16. A review of factors influencing the incidence and severity of plaque-induced gingivitis.

    Science.gov (United States)

    Trombelli, L; Farina, R

    2013-06-01

    An individual variation in the gingival inflammatory response to the dental biofilm has been demonstrated. This variability can be observed between individuals with neither quantitative nor qualitative differences in plaque accumulation. The reported significant differences in gingival inflammatory response under quantitatively and/or qualitatively almost identical bacterial challenge suggest that the gingival response to plaque accumulation may be an individual trait, possibly genetic in origin. The most recent classification of periodontal diseases acknowledges that the clinical expression of plaque-induced gingival inflammation can be substantially modified by systemic factors, either inherent to the host or related to environmental influences. The aim of the present literature review is to describe (i) the factors influencing the development of plaque-induced gingivitis as well as (ii) those metabolic, environmental and systemic factors which have a direct impact on the etiopathogenetic pathway of plaque-induced gingivitis, thus altering the nature or course of the gingival inflammatory response to dental biofilm.

  17. Lasers in esthetic treatment of gingival melanin hyperpigmentation: a review article.

    Science.gov (United States)

    Bakhshi, Mahin; Rahmani, Somayeh; Rahmani, Ali

    2015-11-01

    The health and suitability of mouth components play an important role towards defining facial attractiveness. An important component of the oral cavity is the color of the gingival tissue. Gingival melanin hyperpigmentation is caused by several reasons and affects people across ethnicity, race, age, and both gender. Lasers are presently being used for gingival melanin depigmentation. In this article, we reviewed studies on laser parameters, duration of gingival healing, pain perception during and after the operation, scores used for the evaluation of gingival melanin hyperpigmentation, follow-up period, treatment results, and recurrence reports. We conclude that laser ablation for gingival depigmentation is one of the most pleasant, reliable, acceptable, and impressive techniques available for treating gingival melanin hyperpigmentation.

  18. Management of amlodipine-induced gingival enlargement: Series of three cases

    Directory of Open Access Journals (Sweden)

    Srivastava Amit

    2010-01-01

    Full Text Available Gingival enlargement is one of the side effects associated with certain drugs. Amlodipine, a calcium channel blocker, used as antihypertensive drug has been found associated with gingival hyperplasia. This case series presents diagnosis and management of amlodipine-induced gingival hyperplasia. Amlodipine-induced gingival enlargement was diagnosed and managed by thorough scaling and root planning. Drug substitution and surgical intervention was performed in first two cases. The pathogenesis of gingival enlargement is uncertain and the treatment is still largely limited to the maintenance of an improved level of oral hygiene and surgical removal of the overgrown tissue. Several factors may influence the relationship between the drugs and gingival tissues as discussed by Seymour et al. Meticulous oral hygiene maintenance, switchover to alternative drug, professional scaling and root planning and surgical excision of enlarged gingival tissue may help overcome the effect of these drugs.

  19. Porcine collagen matrix for treating gingival recession. Randomized clinical trial.

    Directory of Open Access Journals (Sweden)

    Yuri Castro

    2014-03-01

    Full Text Available Achieving root coverage after exposure caused by gingival recession is one of the main goals of reconstructive periodontal surgery. Even though a large variety of techniques and mucogingival grafting procedures are available, their long-term results are not clear yet. Therefore, this study aimed to compare clinical effectiveness of the porcine collagen matrix with subepithelial connective graft for treating Miller class I and II gingival recessions. Materials and methods: The randomized clinical trial included twelve patients assigned to two groups. In the first group (experimental, six patients were treated using collagen matrix (mean age, 54.3±5.6 years; mean recession 2. 67±1.03mm. Another group (control of six patients was treated using connective grafts (mean age, 57.1± 2.7 years; mean recession 4.33±1.03mm. All patients underwent periodontal evaluation and pre-surgical preparation including oral hygiene instruction and supragingival scaling. Gingival recessions were exposed through partial thickness flaps where the grafts and matrices were placed. Patients were assessed periodically until complete healing of tissue. Results: Root coverage parameters, amount of keratinized gingiva, gingival biotype and clinical attachment level were evaluated. The root coverage percentage for the group using connective graft was 24.7±13.5% and 16.6±26.8% for the one treated with the matrix. The amount of increased keratinized tissue was 4.33±2.06mm and 4.5±0.83mm for the control and experimental group respectively. Both groups increased gingival biotypes from thin to thick at 100%. The final clinical attachment level was 4.17±3.17±04mm for the control group and 0.98mm for the experimental group. There were significant differences between the outcome of gingival recession and clinical attachment. Conclusion: Results indicate both techniques, besides being predictable, are useful for improving clinical parameters when treating gingival recessions

  20. Cambios histopatológicos de la mucosa gingival en masticadores de hoja de coca varones del distrito de Laraos, provincia de Yauyos

    OpenAIRE

    Ayón Haro, Esperanza Raquel; Chu Morales, María del Pilar

    2005-01-01

    Describe los cambios histopatológicos de la mucosa gingival. El estudio se realizó en el Puesto de Salud del Distrito de Laraos, provincia de Yauyos, en donde el hábito de la masticación de hojas de coca sigue vigente. El grupo de escogido estuvo conformado por 30 masticadores de hoja coca, varones de 40 a 61 años de edad y el grupo control por 30 no masticadores de hoja de coca, cuyas edades y características fueron similares al grupo de estudio. Para la selección de la muestra se u...

  1. Plaque and gingivitis in the deciduous and permanent dentition.

    Science.gov (United States)

    Ramberg, P W; Lindhe, J; Gaffar, A

    1994-08-01

    The aim of the present investigation was to monitor de novo plaque formation and associated alterations of the gingival conditions in the deciduous, mixed and permanent dentition in man. 31 volunteers, divided into 3 study groups participated in the trial. Group 1 was made up of 11 subjects, 4-6 years of age (deciduous dentition), group 2 comprised of 10 subjects, 8-9 years of age (mixed dentition) and group 3 included 10 subjects, 14-16 years of age (permanent dentition). After a screening examination, each participant received detailed instruction in a proper oral hygiene technique and was subjected to professional tooth cleaning. The professional debridement and the oral hygiene instruction were repeated after 1 week. After another week, a given day was termed Day 0 and a baseline examination was performed. This examination included assessments of plaque and gingivitis. Each subject received an additional, comprehensive professional tooth cleaning and was asked to abstain from all mechanical oral hygiene measures. Re-examinations were performed after 3 and 7 days. The findings demonstrated that: (i) during a 7-day period of no active oral hygiene, subjects with a mixed or a permanent dentition formed visible amounts of plaque and developed modest signs of gingivitis; (ii) during the 7 days of the trial, young subjects with a fully erupted deciduous dentition formed less plaque than the older subjects, and failed to respond to de novo plaque formation with enhanced signs of gingivitis; (iii) in subjects with a mixed dentition, the amount of plaque formed during the 7 days of experiment and the matching gingivitis development were similar in the deciduous and permanent tooth segments of the dentition.

  2. The effect of triclosan on mediators of gingival inflammation.

    Science.gov (United States)

    Gaffar, A; Scherl, D; Afflitto, J; Coleman, E J

    1995-06-01

    Triclosan (2,4,4',-trichloro-2'-hydroxydiphenylether) is a well-known and widely used nonionic antibacterial agent which has recently been introduced in toothpastes and mouthrinses. The efficacy of triclosan-containing toothpaste and mouthrinse to reduce both plaque and gingivitis in long-term clinical trials has been well documented. Until recently, it was generally assumed that triclosan's effect on gingival inflammation was due to its antimicrobial and anti-plaque effect. It has now become apparent that triclosan may have a direct anti-inflammatory effect on the gingival tissues. Several in vitro studies were conducted to evaluate the effect of triclosan on 4 primary enzymes of the pathways of arachidonic acid metabolism, cyclo-oxygenase 1, cyclo-oxygenase 2, 5-lipoxygenase and 15-lipoxygenase. These pathways lead to the production of known mediators of inflammation such as the prostaglandins, leukotrienes and lipoxins. Triclosan inhibited both cyclooxygenase 1 and cyclo-oxygenase 2 with IC-50 values of 43 microM and 227 microM, respectively. Triclosan also inhibited 5-lipoxygenase with an IC-50 of 43 microM. The 15-lipoxygenase was similarly inhibited by triclosan with an IC-50 of 61 microM. Hence, triclosan has the ability to inhibit both the cyclo-oxygenase and lipoxygenase pathways of arachidonic acid metabolism with similar efficacy. In cell culture experiments, it was found that triclosan inhibited IL-1 beta induced prostaglandin E2 production by human gingival fibroblasts in a concentration dependent manner, and at relatively low concentrations. These data, taken together, indicate that triclosan can inhibit formation of several important mediators of gingival inflammation.(ABSTRACT TRUNCATED AT 250 WORDS)

  3. Prevalence of gingival recession after orthodontic tooth movements.

    Science.gov (United States)

    Morris, Jason W; Campbell, Phillip M; Tadlock, Larry P; Boley, Jimmy; Buschang, Peter H

    2017-05-01

    This study was designed to evaluate the long-term prevalence of gingival recession after orthodontic tooth movements, focusing on the effects of mandibular incisor proclination and expansion of maxillary posterior teeth. Records of 205 patients (162 female, 43 male) were obtained from 2 private practice orthodontists. Using pretreatment (age, 14.0 ± 5.9 years) and posttreatment (age, 16.5 ± 6.0 years) lateral cephalograms and dental models, mandibular incisor proclination and maxillary arch widths were measured. Gingival recession was measured based on posttreatment and postretention (age, 32.3 ± 8.5 years) intraoral photographs and models. Associations between tooth movements and gingival recession were evaluated statistically. Only 5.8% of teeth exhibited recession at the end of orthodontic treatment (only 0.6% had recession >1 mm). After retention, 41.7% of the teeth showed recession, but the severity was limited (only 7.0% >1 mm). There was no relationship between mandibular incisor proclination during treatment and posttreatment gingival recession. Incisors that finished treatment angulated (IMPA) at 95° or greater did not show significantly more recession than did those that finished less than 95°. There were weak positive correlations (r = 0.17-0.41) between maxillary arch width increases during treatment and posttreatment recession. Orthodontic treatment is not a major risk factor for the development of gingival recession. Although greater amounts of maxillary expansion during treatment increase the risks of posttreatment recession, the effects are minimal. Copyright © 2017 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.

  4. Smad2 overexpression enhances adhesion of gingival epithelial cells.

    Science.gov (United States)

    Hongo, Shoichi; Yamamoto, Tadashi; Yamashiro, Keisuke; Shimoe, Masayuki; Tomikawa, Kazuya; Ugawa, Yuki; Kochi, Shinsuke; Ideguchi, Hidetaka; Maeda, Hiroshi; Takashiba, Shogo

    2016-11-01

    Gingival epithelial cells play an important role in preventing the initiation of periodontitis, by their hemidesmosomal adhesion to the tooth root surface. Adhesion requires integrin-extracellular matrix (ECM) interactions that are intricately regulated by transforming growth factor-β (TGF-β) signaling. However, the mechanisms underlying the interplay between adhesion molecules and TGF-β, especially the respective roles of Smad2 and Smad3, remain elusive. In this study, we examined the effects of Smad overexpression on gingival epithelial cell adhesion and expression profiles of integrin and ECM-related genes. Human gingival epithelial cells immortalized by the SV40 T-antigen were transfected with Smad2- and Smad3-overexpression vectors. A cell adhesion assay involving fluorescence detection of attached cells was performed using the ArrayScan imaging system. Real-time PCR was performed to examine the kinetics of integrin and ECM gene expression. In vitro and in vivo localization of adhesion molecules was examined by immunofluorescence analysis. By using SB431542, a specific inhibitor of the TGF-β type I receptor, Smad2/3 signaling was confirmed to be dominant in TGF-β1-induced cell adhesion. The Smad2-transfectant demonstrated higher potency for cell adhesion and integrin expression (α2, α5, β4, and β6) than the Smad3-transfectant, whereas little or no change in ECM expression was observed in either transfectant. Moreover, the gingival epithelium of transgenic mice that overexpressed Smad2 driven by the keratin 14 promoter showed increased integrin α2 expression. These findings indicate the crucial role of Smad2 in increased adhesion of gingival epithelial cells via upregulation of integrin α2. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Prevalence of gingival biotype and its relationship to clinical parameters.

    Science.gov (United States)

    Shah, Rucha; Sowmya, N K; Mehta, D S

    2015-09-01

    The dimensions of gingiva and different parts of the masticatory mucosa have a profound impact in periodontics as it governs the way; the gingival tissue reacts to various physical, chemical, or bacterial insults. The purpose of the following study was to assess the gingival thickness (GT) and correlate it to gender, presence of recession, and width of keratinized gingiva (WKG) in a subset of the Indian population. A total of 400 subjects in the age range of 20-35 years (200 males and 200 females) were included in the study. Clinical parameters such as probing depth, recession depth, WKG, and GT were recorded for all the patients. The prevalence of thin biotype was 43.25%, and that of thick gingival biotype was 56.75%. The mean GT of central incisor, lateral incisor, and canine in Group I was 1.11 ± 0.17, 1.01 ± 0.16, and 0.82 ± 0.17 mm, respectively. No significant association was observed between the gender and the presence of gingival recession to GT. The mean WKG of central incisor, lateral incisor, and canine in Group I was 4.38 ± 1.18, 5.18 ± 1.25, 4.16 ± 1.16 mm, respectively. A positive correlation exists between WKG and the GT (P biotype is 56.75% versus 43.25%, respectively, and there is no significant relationship between age, gender, and the presence of recession to gingival biotype. A positive correlation exists between WKG and the GT.

  6. The clinical application of hyaluronic acid in gingivitis therapy.

    Science.gov (United States)

    Pistorius, Alexander; Martin, Monika; Willershausen, Brita; Rockmann, Phillip

    2005-01-01

    The efficacy of a topical application of hyaluronic acid (HA) was tested for treating gingivitis. Sixty nonsmoking outpatients in good general condition, with clinical signs of gingivitis, were included in the study. Forty patients (HA group, 20 men, 20 women; age: 32.8 +/- 11.3 years) used a spray containing HA 5 times daily over a period of 1 week. The control group consisted of 20 patients (10 men, 10 women; age: 31.3 +/- 9.3 years). The clinical parameters DMF-T (decayed, missed, filled teeth) index, approximal plaque index, sulcus bleeding index, papilla bleeding index, and gingival crevicular fluid were measured at baseline (T1), after 3 days (T2), and after 7 days (T3). A reduction in the sulcus bleeding index of the HA group (T1: 72.9 +/- 19.5%) to 50.3 +/- 21.1% was noted at T2, and at T3 the sulcus bleeding index was 40.7 +/- 23.0%. The papilla bleeding index values of the HA group were 1.6 at T1, 1.0 at T2, and 0.7 at T3. The gingival crevicular fluid showed significant reductions in the HA group. At T1 the recorded mean value was 16.3, at T2 it was 11.8, and at T3 it was 7.9. Only insignificant changes were observed in the respective indices of the control group. There were no significant alterations in the plaque values of either group throughout the study period. The results obtained by this study demonstrate that the topical application of an HA-containing preparation represents a potentially useful adjunct in the therapy of gingivitis, although its use does not diminish the need for plaque reduction as a primary therapeutic measure.

  7. Human Memory B Cells in Healthy Gingiva, Gingivitis, and Periodontitis.

    Science.gov (United States)

    Mahanonda, Rangsini; Champaiboon, Chantrakorn; Subbalekha, Keskanya; Sa-Ard-Iam, Noppadol; Rattanathammatada, Warattaya; Thawanaphong, Saranya; Rerkyen, Pimprapa; Yoshimura, Fuminobu; Nagano, Keiji; Lang, Niklaus P; Pichyangkul, Sathit

    2016-08-01

    The presence of inflammatory infiltrates with B cells, specifically plasma cells, is the hallmark of periodontitis lesions. The composition of these infiltrates in various stages of homeostasis and disease development is not well documented. Human tissue biopsies from sites with gingival health (n = 29), gingivitis (n = 8), and periodontitis (n = 21) as well as gingival tissue after treated periodontitis (n = 6) were obtained and analyzed for their composition of B cell subsets. Ag specificity, Ig secretion, and expression of receptor activator of NF-κB ligand and granzyme B were performed. Although most of the B cell subsets in healthy gingiva and gingivitis tissues were CD19(+)CD27(+)CD38(-) memory B cells, the major B cell component in periodontitis was CD19(+)CD27(+)CD38(+)CD138(+)HLA-DR(low) plasma cells, not plasmablasts. Plasma cell aggregates were observed at the base of the periodontal pocket and scattered throughout the gingiva, especially apically toward the advancing front of the lesion. High expression of CXCL12, a proliferation-inducing ligand, B cell-activating factor, IL-10, IL-6, and IL-21 molecules involved in local B cell responses was detected in both gingivitis and periodontitis tissues. Periodontitis tissue plasma cells mainly secreted IgG specific to periodontal pathogens and also expressed receptor activator of NF-κB ligand, a bone resorption cytokine. Memory B cells resided in the connective tissue subjacent to the junctional epithelium in healthy gingiva. This suggested a role of memory B cells in maintaining periodontal homeostasis. Copyright © 2016 by The American Association of Immunologists, Inc.

  8. Subgingival bacterial colonization profiles correlate with gingival tissue gene expression

    Directory of Open Access Journals (Sweden)

    Handfield Martin

    2009-10-01

    Full Text Available Abstract Background Periodontitis is a chronic inflammatory disease caused by the microbiota of the periodontal pocket. We investigated the association between subgingival bacterial profiles and gene expression patterns in gingival tissues of patients with periodontitis. A total of 120 patients undergoing periodontal surgery contributed with a minimum of two interproximal gingival papillae (range 2-4 from a maxillary posterior region. Prior to tissue harvesting, subgingival plaque samples were collected from the mesial and distal aspects of each tissue sample. Gingival tissue RNA was extracted, reverse-transcribed, labeled, and hybridized with whole-genome microarrays (310 in total. Plaque samples were analyzed using checkerboard DNA-DNA hybridizations with respect to 11 bacterial species. Random effects linear regression models considered bacterial levels as exposure and expression profiles as outcome variables. Gene Ontology analyses summarized the expression patterns into biologically relevant categories. Results Wide inter-species variation was noted in the number of differentially expressed gingival tissue genes according to subgingival bacterial levels: Using a Bonferroni correction (p -7, 9,392 probe sets were differentially associated with levels of Tannerella forsythia, 8,537 with Porphyromonas gingivalis, 6,460 with Aggregatibacter actinomycetemcomitans, 506 with Eikenella corrodens and only 8 with Actinomyces naeslundii. Cluster analysis identified commonalities and differences among tissue gene expression patterns differentially regulated according to bacterial levels. Conclusion Our findings suggest that the microbial content of the periodontal pocket is a determinant of gene expression in the gingival tissues and provide new insights into the differential ability of periodontal species to elicit a local host response.

  9. C-Reactive Protein in Peripheral Blood of Patients with Chronic and Aggressive Periodontitis, Gingivitis, and Gingival Recessions.

    Science.gov (United States)

    Podzimek, Stepan; Mysak, Jaroslav; Janatova, Tatjana; Duskova, Jana

    2015-01-01

    CRP is a plasma protein that reflects a measure of the acute phase response to inflammation and is one of the markers of choice in monitoring this response. CRP can be used for the prediction and early detection of periodontal disease. The aim of this study was to compare and evaluate the systemic levels of CRP in the peripheral blood samples of patients with chronic and aggressive periodontitis, gingivitis, and gingival recessions and compare them with periodontal clinical parameters. All patients (N = 158) were examined prior to the initiation of periodontal treatment. Patients were divided into four groups. Group A consisted of 26 patients with aggressive periodontitis, Group B consisted of 111 patients with chronic periodontitis, Group C consisted of 13 patients with gingivitis, and Group D consisted of 8 patients with gingival recessions. Our study results indicate that CRP levels increase subsequently with the severity of the periodontal disease and that the bleeding on probing index showed much better positive correlation with the CRP levels compared to the pocket depth index in both periodontitis patients groups, especially in aggressive periodontitis patients.

  10. Chlorhexidine mouthrinse as an adjunctive treatment for gingival health.

    Science.gov (United States)

    James, Patrice; Worthington, Helen V; Parnell, Carmel; Harding, Mairead; Lamont, Thomas; Cheung, Andrea; Whelton, Helen; Riley, Philip

    2017-03-31

    Dental plaque associated gingivitis is a reversible inflammatory condition caused by accumulation and persistence of microbial biofilms (dental plaque) on the teeth. It is characterised by redness and swelling of the gingivae (gums) and a tendency for the gingivae to bleed easily. In susceptible individuals, gingivitis may lead to periodontitis and loss of the soft tissue and bony support for the tooth. It is thought that chlorhexidine mouthrinse may reduce the build-up of plaque thereby reducing gingivitis. To assess the effectiveness of chlorhexidine mouthrinse used as an adjunct to mechanical oral hygiene procedures for the control of gingivitis and plaque compared to mechanical oral hygiene procedures alone or mechanical oral hygiene procedures plus placebo/control mouthrinse. Mechanical oral hygiene procedures were toothbrushing with/without the use of dental floss or interdental cleaning aids and could include professional tooth cleaning/periodontal treatment.To determine whether the effect of chlorhexidine mouthrinse is influenced by chlorhexidine concentration, or frequency of rinsing (once/day versus twice/day).To report and describe any adverse effects associated with chlorhexidine mouthrinse use from included trials. Cochrane Oral Health's Information Specialist searched the following databases: Cochrane Oral Health's Trials Register (to 28 September 2016); the Cochrane Central Register of Controlled Trials (CENTRAL; 2016, Issue 8) in the Cochrane Library (searched 28 September 2016); MEDLINE Ovid (1946 to 28 September 2016); Embase Ovid (1980 to 28 September 2016); and CINAHL EBSCO (Cumulative Index to Nursing and Allied Health Literature; 1937 to 28 September 2016). We searched ClinicalTrials.gov and the World Health Organization International Clinical Trials Registry Platform for ongoing trials. No restrictions were placed on the language or date of publication when searching the electronic databases. We included randomised controlled trials assessing

  11. Criptococosis gingival en un paciente con SIDA

    OpenAIRE

    Delgado-Azañero, Wilson A.; Facultad de Estomatología, Universidad Peruana Cayetano Heredia. Lima; Meneses Rivadeneyra, Leopoldo; Facultad de Estomatología, Universidad Peruana Cayetano Heredia. Lima,; Gotuzzo Herencia, Eduardo; Instituto de Medicina Tropical “Alexander von Humboldt”. Universidad Peruana Cayetano Heredia. Lima,; Bustamante, Beatriz; Instituto de Medicina Tropical “Alexander von Humboldt”. Universidad Peruana Cayetano Heredia. Lima,

    2014-01-01

    La criptococosis es una infección micótica que afecta a personas con o sin inmunosupresión. Sepresenta principalmente como una infección pulmonar crónica. La mayoría de casos enmucosa oral han sido reportados en pacientes con SIDA que cursaban con la forma diseminadade la infección. Se presenta un paciente varón de 36 años con SIDA, cuyo diagnóstico decriptococosis se estableció por biopsias de las encías. El cuadro oral se caracterizó poragrandamientos gingivales del sector ántero superior e...

  12. Gingival recession in young adults: occurrence, severity, and relationship to past orthodontic treatment and oral piercing.

    Science.gov (United States)

    Slutzkey, Shimshon; Levin, Liran

    2008-11-01

    Gingival recession can be localized or generalized and associated with at least 1 tooth surface. As a result, gingival recession leads to root surface exposure, often causing esthetic impairment, fear of tooth loss, increased susceptibility for root caries, and dentin hypersensitivity. The prevalence, extent, and severity of gingival recession in a young adult Israeli population were evaluated, and the relationship between orthodontic therapy and other potential risk indicators and gingival recession was assessed. Our cohort included 303 consecutive healthy patients who had routine dental examinations at a military dental center. Information was collected regarding age, smoking habits, oral piercing, oral hygiene habits, and past orthodontic treatment. Clinical examination included visible gingival inflammation, visible dental plaque, and gingival recession on the facial aspects of all teeth. Gingival recession was found in 14.6% of the subjects and in 1.6% of all examined teeth. The prevalence, extent, and severity of recession correlated with past orthodontic treatment. A negative correlation was found between plaque on the buccal tooth aspect and gingival recession. There was no correlation between gingivitis or smoking habits and recession. Prevalence was related to oral piercing. Gingival recession is not uncommon in young adults and is related to past orthodontic treatment and oral piercing. Patients undergoing orthodontic treatment or about to pierce the tongue or lips should be advised regarding these findings.

  13. The gingival biotype in a cohort of Chinese subjects with and without history of periodontal disease.

    Science.gov (United States)

    Liu, F; Pelekos, G; Jin, L J

    2017-12-01

    The present study aimed to determine the gingival biotype in Chinese subjects with and without a history of periodontal disease. Thirty periodontally healthy subjects and 20 subjects with treated chronic periodontitis were recruited. The mid-buccal gingival thickness of upper central and lateral incisors was measured by a customized caliper in all subjects. The crown length and crown width of these teeth were recorded in the healthy group, while gingival recession was measured in the periodontitis group. These outcome measures were compared among the groups and sub-groups, and the correlation of gingival biotypes with clinical parameters was analyzed. The mean thickness of gingiva in the 30 periodontally healthy subjects was 1.05±0.31 mm (0.47-1.57 mm). The males exhibited a greater crown length than the females (Pbiotype as measured by gingival thickness was significantly correlated with gingival recession (r=-.240, P=.032), while a stronger correlation was found among the 42 sites with bleeding on probing prior to periodontal treatment (r=-.382, P=.013). This study shows that gingival biotype measured by gingival thickness in subjects with treated periodontitis is significantly correlated with gingival recession. Further study could clarify the clinical implications of gingival biotype in the management of periodontal patients. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  14. Monocyte chemotactic protein-1, RANTES and macrophage migration inhibitory factor levels in gingival crevicular fluid of metabolic syndrome patients with gingivitis.

    Science.gov (United States)

    Gürkan, Ali; Eren, Gülnihal; Çetinkalp, Şevki; Akçay, Yasemin Delen; Emingil, Gülnur; Atilla, Gül

    2016-09-01

    The aim of the present study was to determine gingival crevicular fluid (GCF) levels of monocyte chemotactic protein-1 (MCP-1), regulated on activation, normal T-cell expressed and secreted protein (RANTES) and macrophage migration inhibitory factor (MIF) in metabolic syndrome patients with gingivitis. Twenty metabolic syndrome patients with gingivitis (MSG), 20 MetS patients with clinically healthy periodontium (MSH), 20 systemically healthy subjects with gingivitis and 20 subjects who were both systemically and periodontally healthy were included. Periodontal and systemical parameters were recorded. GCF MCP-1, RANTES and MIF levels were assayed by enzyme-linked immunosorbent assay method. MSG and MSH groups had elevated blood pressure, triglyceride, waist circumference and fasting glucose values in comparison to gingivitis and healthy groups (Pgingivitis groups when compared to those of the MSH and healthy groups (Pgingivitis group had higher MCP-1, RANTES and MIF levels compared to the healthy group (P=0.011, P=0.0001, P=0.011 respectively). The RANTES level of MSG group was significantly higher than those of the gingivitis group (P=0.01), but MCP-1 and MIF levels were similar in the MSG and gingivitis groups (P>0.05). Elevated levels of GCF RANTES in MetS patients with gingivitis might associate with the presence of increased gingival inflammation by MetS. Low-grade systemic inflammation associated with MetS and adipose tissue-derived RANTES might lead to altered GCF RANTES levels in the presence of gingival inflammation. Copyright © 2016. Published by Elsevier Ltd.

  15. Gene polymorphism in amlodipine induced gingival hyperplasia: a case report.

    Science.gov (United States)

    Charles, Nsc; Ramesh, V; Babu, Kennedy Spk; Premalatha, B

    2012-10-01

    The management of cardiovascular disorders poses a dilemma for the medical fraternity. Calcium channel blockers are one of the most commonly used drugs for the management of this disorder, and it is also a well known fact that they are one of the most common group of drugs responsible for causing gingival over growth as one of their adverse effects. Amlodipine is a new generation hypertensive, which has found wide acceptance and usage due to its duration of action. Even with all its benefits as a potent hypertensive, its effect on gingival tissues is what causes concern to the patient and dental surgeon equally. The objective of this article is to create awareness regarding the adverse oral effects of amlodipine, its underlying mechanism of action in bringing about this adverse reaction, along with providing a brief review of the pharmacologic profile of this drug.

  16. Desquamative gingivitis as a manifestation of chronic mucocutaneous disease.

    Science.gov (United States)

    Gagari, Eleni; Damoulis, Petros D

    2011-03-01

    Desquamative gingivitis (DG) is a clinical descriptive term indicating "peeling gums". DG is usually the result of a disease process that causes separation of the epithelium from the underlying connective tissue in the oral masticatory mucosa. DG may be a manifestation of several mucocutaneous diseases, most commonly cicatricial pemphigoid, pemphigus vulgaris and lichen planus. Correct diagnosis of the underlying disease in DG patients requires careful clinical observation, detailed examination of medical history, biopsy and histopathological examination of the lesions as well as more specialized tests such as direct and indirect immunofluorescence. Treatment of DG consists of treating the underlying disease and often requires the use of immunosuppressive agents, such as corticosteroids. Elimination of local gingival irritants, such as dental plaque and calculus, can significantly improve the treatment outcome. © The Authors • Journal compilation © Blackwell Verlag GmbH, Berlin.

  17. Efficacy of three toothbrushes on established gingivitis and plaque.

    Science.gov (United States)

    Sowinski, Joseph; Petrone, Dolores M; Wachs, Gerald N; Chaknis, Patricia; Kemp, James; Sprosta, Al A; Devizio, William

    2008-12-01

    To evaluate the efficacy of three toothbrushes [Colgate 3600 Deep Clean (AFT version), the Colgate 3600 Deep Clean (stapled version) and the Oral B Indicator] on the removal of established gingivitis and plaque. This examiner-blind, three-treatment, parallel clinical research study assessed plaque removal via the comparison of pre-to- post-brushing and 4-week plaque removal measured by the Rustogi Modification of the Modified Navy Plaque Index. This study also assessed gingivitis using the Löe & Silness Gingival Index. Qualifying adult male and female subjects from the Northern New Jersey area reported to the study site after refraining from any oral hygiene procedures for 12 hours; and from eating, drinking, or smoking for 4 hours. Following an examination for gingivitis and plaque (pre-brushing), they were randomized into three balanced groups, each group using one of the three study toothbrushes in the order specified by a pre-determined randomization plan. Subjects were instructed to brush their teeth for 1 minute under supervision with their assigned toothbrush and a commercially-available toothpaste (Colgate Cavity Protection), after which they were once again evaluated for plaque (post-brushing). Subjects were then dismissed from the study site with the toothpaste and their assigned toothbrush to use at home twice daily for the next 4 weeks. They again reported to the study site at which time they were evaluated for plaque and gingivitis. 109 subjects complied with the protocol and completed the clinical study. For plaque removal, comparisons were made for whole mouth, at the gingival margin and at interproximal sites. The results of the study indicated that all three test toothbrushes provided statistically significantly reductions in pre- to post-brushing plaque index scores of up to 44.0%, 38.6% and 23.6% respectively, after a single toothbrushing. Relative to the Oral B Indicator toothbrush, the Colgate 360 degree Deep Clean toothbrush (AFT version) and

  18. Pink esthetics in periodontics – Gingival depigmentation: A case series

    Science.gov (United States)

    Thangavelu, Arthiie; Elavarasu, Sugumari; Jayapalan, Piranitha

    2012-01-01

    Smile expresses a feeling of joy, success, sensuality, affection, and courtesy, and reveals self-confidence and kindness. The harmony of the smile is determined not only by the shape, the position, and the color of the teeth, but also by the gingival tissues. Although melanin pigmentation of the gingiva is completely benign and does not present a medical problem, complaints of “black gums” are common, particularly in patients having a very high smile line. Thus, perio-esthetic treatment modalities strive to achieve a harmonious inter-relationship of the pink with white, which is imperative of all treatment procedures. For depigmentation of gingival, different treatment modalities have been reported, such as bur abrasion, scraping, partial thickness flap, cryotherapy, electrosurgery, and laser. In the present case series, scraping, electrosurgery, and diode laser have been tried for depigmentation, which are simple, effective, and yield good results, along with good patient satisfaction. PMID:23066249

  19. Muco-gingival surgery for the treatment of periodontal recession

    Directory of Open Access Journals (Sweden)

    Omelio Fontaine Machado

    2015-06-01

    Full Text Available Periodontal recession is the total or partial loss of the gum that covers the root, having as a result an apical gingival margin. A therapeutic option is the muco-gingival surgery, in order to try to cover the exposed root of the tooth. This study presents the case of a 40-year-old white male patient, with a past medical history of referral from primary care for having a degree II periodontal recession at the 31, caused by an occlusion trauma. There were no signs of dental mobility and there was a good oral hygiene. Before the indication of medicinal treatment and the order of hematological studies, a free gum graft was performed to reduce the level of periodontal retraction. The patient was followed at office during three months. The patient progressed satisfactorily from an esthetic viewpoint.

  20. Can Chemical Mouthwash Agents Achieve Plaque/Gingivitis Control?

    Science.gov (United States)

    Van der Weijden, Fridus A; Van der Sluijs, Eveline; Ciancio, Sebastian G; Slot, Dagmar E

    2015-10-01

    Also note that structured abstracts are not allowed per journal style: What is the effect of a mouthwash containing various active chemical ingredients on plaque control and managing gingivitis in adults based on evidence gathered from existing systematic reviews? The summarized evidence suggests that mouthwashes containing chlorhexidine(CHX) and essential oils (EO) had a large effect supported by a strong body of evidence. Also there was strong evidence for a moderate effect of cetylpyridinium chloride(CPC). Evidence suggests that a CHX mouthwash is the first choice, the most reliable alternative is EO. No difference between CHX and EO with respect to gingivitis was observed. Copyright © 2015 Elsevier Inc. All rights reserved.

  1. Oral gingival myiasis: A rare case report and literature review.

    Science.gov (United States)

    Sharma, Dheeraj; Kumar, Sandeep; Parashar, Pranav; Naphade, Vihang Vinod

    2015-01-01

    Myiasis is a universal term for extreme infection by the parasitic fly larvae that feed on their host living/dead tissue. Gingival myiasis is a rare disease in the humans associated with poor oral hygiene, suppurative oral lesions, alcoholism, and senility, among other conditions. We present a case of gingival myiasis in the maxillary anterior region on the palatal surface in a 21-year-old mentally challenged male with moderate periodontitis and neurologic deficit. The diagnosis was made on the presence of larvae in the lesion. Treatment done was a manual removal of the larvae, one by one, with the help of the clinical forceps, surgical debridement of the oral wound, and subsequent management of the periodontal disease.

  2. Oral gingival myiasis: A rare case report and literature review

    Directory of Open Access Journals (Sweden)

    Dheeraj Sharma

    2015-01-01

    Full Text Available Myiasis is a universal term for extreme infection by the parasitic fly larvae that feed on their host living/dead tissue. Gingival myiasis is a rare disease in the humans associated with poor oral hygiene, suppurative oral lesions, alcoholism, and senility, among other conditions. We present a case of gingival myiasis in the maxillary anterior region on the palatal surface in a 21-year-old mentally challenged male with moderate periodontitis and neurologic deficit. The diagnosis was made on the presence of larvae in the lesion. Treatment done was a manual removal of the larvae, one by one, with the help of the clinical forceps, surgical debridement of the oral wound, and subsequent management of the periodontal disease.

  3. Aesthetic Depigmentation of Gingival Smoker's Melanosis Using Carbon Dioxide Lasers.

    Science.gov (United States)

    Monteiro, Luis Silva; Costa, José Adriano; da Câmara, Marco Infante; Albuquerque, Rui; Martins, Marco; Pacheco, José Júlio; Salazar, Filomena; Figueira, Fernando

    2015-01-01

    Melanic pigmentation results from melanin produced by the melanocytes present in the basal layer of the oral epithelium. One of the most common causes of oral pigmentation is smoker melanosis, a condition associated with the melanocyte stimulation caused by cigarette smoke. This paper aims to illustrate the use of a carbon dioxide laser in the removal of the gingival melanic pigmentation for aesthetic reasons in a 27-year-old female patient with history of a smoking habit. The carbon dioxide laser vaporisation was performed on the gingival mucosa with effective and quick results and without any complications or significant symptoms after the treatment. We conclude that a carbon dioxide laser could be a useful, effective, and safe instrument to treat the aesthetic complications caused by oral smoker melanosis.

  4. Pink esthetics in periodontics - Gingival depigmentation: A case series.

    Science.gov (United States)

    Thangavelu, Arthiie; Elavarasu, Sugumari; Jayapalan, Piranitha

    2012-08-01

    Smile expresses a feeling of joy, success, sensuality, affection, and courtesy, and reveals self-confidence and kindness. The harmony of the smile is determined not only by the shape, the position, and the color of the teeth, but also by the gingival tissues. Although melanin pigmentation of the gingiva is completely benign and does not present a medical problem, complaints of "black gums" are common, particularly in patients having a very high smile line. Thus, perio-esthetic treatment modalities strive to achieve a harmonious inter-relationship of the pink with white, which is imperative of all treatment procedures. For depigmentation of gingival, different treatment modalities have been reported, such as bur abrasion, scraping, partial thickness flap, cryotherapy, electrosurgery, and laser. In the present case series, scraping, electrosurgery, and diode laser have been tried for depigmentation, which are simple, effective, and yield good results, along with good patient satisfaction.

  5. Pink esthetics in periodontics - Gingival depigmentation: A case series

    Directory of Open Access Journals (Sweden)

    Arthiie Thangavelu

    2012-01-01

    Full Text Available Smile expresses a feeling of joy, success, sensuality, affection, and courtesy, and reveals self-confidence and kindness. The harmony of the smile is determined not only by the shape, the position, and the color of the teeth, but also by the gingival tissues. Although melanin pigmentation of the gingiva is completely benign and does not present a medical problem, complaints of "black gums" are common, particularly in patients having a very high smile line. Thus, perio-esthetic treatment modalities strive to achieve a harmonious inter-relationship of the pink with white, which is imperative of all treatment procedures. For depigmentation of gingival, different treatment modalities have been reported, such as bur abrasion, scraping, partial thickness flap, cryotherapy, electrosurgery, and laser. In the present case series, scraping, electrosurgery, and diode laser have been tried for depigmentation, which are simple, effective, and yield good results, along with good patient satisfaction.

  6. Anestesia para cesariana em paciente com hiperplasia adrenal congênita: relato de caso Anestesia para cesárea en paciente con hiperplasia adrenal congénita: relato de caso Anesthesia for cesarean section in a patient with congenital adrenal hyperplasia: case report

    Directory of Open Access Journals (Sweden)

    Mrinalini Balki

    2004-12-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: O objetivo deste relato de caso é ilustrar a conduta anestésica para cesariana em paciente portadora da forma não clássica de hiperplasia adrenal congênita (HAC e revisar as manifestações clínicas e a conduta nas suas várias formas durante a gestação. RELATO DO CASO: Paciente primigrávida, 32 anos, portadora da forma não clássica de HAC foi admitida com quadro de retardo de crescimento intra-uterino, com 28 semanas de gestação. Suas características clínicas incluíam obesidade mórbida, hipertensão arterial leve e uso crônico de glicocorticóides. Com 29 semanas de gestação, a paciente foi submetida à cesariana de emergência sob raquianestesia, observando-se administração de esteróides no período peri-operatório. Mãe e recém-nascido apresentaram boa evolução. CONCLUSÕES: A conduta clínica em parturientes portadoras de HAC deve incluir no planejamento os efeitos da corticoterapia crônica, os sinais de insuficiência adrenal e a administração peri-operatória de esteróides. Em relação à anestesia é necessário considerar aspectos relacionados à obesidade e à hipertensão arterial. Uma abordagem multidisciplinar é necessária para garantir um bom resultado materno-fetal.JUSTIFICATIVA Y OBJETIVOS: El objetivo de este relato de caso es ilustrar la conducta anestésica para cesárea en paciente portadora de la forma no clásica de hiperplasia adrenal congénita (HAC y revisar las manifestaciones clínicas y la conducta en sus varias formas durante la gestación. RELATO DEL CASO: Paciente primípara, 32 años, portadora de la forma no clásica de HAC fue admitida con cuadro de retardo de crecimiento intrauterino, con 28 semanas de gestación. Sus características clínicas incluían obesidad mórbida, hipertensión arterial leve y uso crónico de glucocorticóides. Con 29 semanas de gestación, la paciente fue sometida a cesárea de emergencia bajo raquianestesia, observ

  7. Improving gingival smile by means of guided bone regeneration principles

    Directory of Open Access Journals (Sweden)

    Carlos Eduardo de Almeida Ferreira

    Full Text Available ABSTRACT Objective: This study evaluated the effectiveness of guided bone regeneration (GBR carried out with xenogenic bone substitute (Bio-OssTM and collagen resorbable membrane (Bio-GideTM to improve gingival smile (GS in patients with excessive vertical maxillary growth (EVMG. Methods: Twelve healthy women aged between 20 and 49 years old (mean age of 26 years, with 5 mm or more of gingival exposure during fully posed smile (FPS due to EVMG, were included. Baseline digital photographs were taken with standardized head position at rest and FPS. In eight out of 12 cases, crown lengthening procedure was indicated and the initial incision was made 2 to 4 mm from the gingival margin. In four cases, with no indication for crown lengthening procedure, a sulcular incision was performed. GBR was performed in all cases, using micro screws and/or titanium mesh associated with Bio-OssTM and Bio-GideTM. After 10 days, sutures were removed. Recall appointments were scheduled at 1, 6, and 12 months when standardized photographs were again taken. ImageToolTM software was used to measure the gingival exposure (GE during FPS from the standardized close-up smile photographs at baseline and 12 months. Results: GE mean at baseline was 275.44 mm2. After 12 months, patients who undergone exclusively GBR procedure, presented GE reduction of 40.7%, ∆ = 112.01 mm2 (statistically significant, p = 0.12, and patients who had crown lengthening associated with the graft had a reduction of 60%, ∆ = 167.01 mm2. Conclusion: Our results using GBR to improve GS in cases of EVMG showed an exceptionally high patient acceptance and satisfaction. One-year follow-up confirmed stable results.

  8. No association between gingival labial recession and facial type.

    Science.gov (United States)

    Mazurova, Katerina; Renkema, Anne-Marie; Navratilova, Zuzana; Katsaros, Christos; Fudalej, Piotr S

    2016-06-01

    To evaluate if facial type is a predictor of the development of gingival recession. A cohort of 179 orthodontic patients (76 males, 101 females; age before treatment T S = 12.4 years, SD = 0.8) were followed until 5 years post-treatment (T 5 = 20.7 years, SD = 1.2). The presence of recessions was scored ('Yes' or 'No') by two raters on initial (T S), end of treatment (T 0), and post-treatment (T 5) plaster models. A recession was noted (scored 'Yes') if the labial cemento-enamel junction was exposed. The clinical crown heights were measured at T S, T 0, and T 5 as the distances between the incisal edges and the deepest points of the curvature of the vestibulo-gingival margins. Determination of the facial type was based on the inclination of mandibular plane relative to cranial base (Sella-Nasion/Mandibular Plane) and the proportion of posterior to anterior face heights (PFHs; SGo/NMe × 100 per cent) on pre-treatment cephalograms. From T 0 to T 5, the number of subjects with recessions increased from 2 (1.1 per cent) to 24 (13.6 per cent), and the number of recession sites increased from 2 to 39. However, most patients had either one or two recession sites. The mean clinical crown height of mandibular incisors increased by 0.86mm (SD = 0.82, P gingival recession or on the increase of clinical crown heights of mandibular incisors. Facial type is not a predictor of the occurrence of gingival recession. © The Author 2015. Published by Oxford University Press on behalf of the European Orthodontic Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  9. Treatment of Gingival Hyperpigmentation by Diode Laser for Esthetical Purposes

    Science.gov (United States)

    El Shenawy, Hanaa M.; Nasry, Sherine A.; Zaky, Ahmed A.; Quriba, Mohamed A. A.

    2015-01-01

    BACKGROUND: Gingival hyperpigmentation is a common esthetical concern in patients with gummy smile or excessive gingival display. Laser ablation has been recognized recently as the most effective, pleasant and reliable technique. It has the advantage of easy handling, short treatment time, hemostasis, decontamination, and sterilization effect. AIM: In the present study we wanted to explore the efficacy of a 980 nm wavelength diode laser in gingival depigmentation clinically by using both VAS and digital imaging method as means of assessment. METHODS: Diode laser ablation was done for 15 patients who requested cosmetic therapy for melanin pigmented gums. The laser beam delivered by fiberoptic with a diameter of 320 µm, the diode laser system has 980 nm wave lengths and 3 W irradiation powers, in a continuous contact mode in all cases, the entire surface of each pigmented maxillary and mandibular gingiva that required treatment was irradiated in a single session. Clinical examination and digital image analysis were done and the patients were followed up for 3 successive months. RESULTS: There was a statistically significant change in prevalence of bleeding after treatment, as none of the cases showed any signs of bleeding 1 week, 1 month and 3 months after ablation. No statistically significant change was observed in the prevalence of swelling after treatment The VAS evaluation demonstrated that only 4 patients complained of mild pain immediately after the procedure. No pain was perceived from the patients in the rest of the follow up period. There was no statistically significant change in prevalence of pain immediately after treatment compared to pain during treatment. There was a decrease in cases with mild pain after 1 week, 1 month as well as 3 months compared to pain during treatment and immediately after treatment. CONCLUSION: Within the limitations of this study, the use of diode laser was shown to be a safe and effective treatment modality that provides

  10. Treatment of anterior crossbite and its influence on gingival recession

    OpenAIRE

    ANDRADE,Roberta Nascimento; TÔRRES,Flávia Ribeiro; Ferreira, Rogério Frederico Alves; Catharino, Fernanda

    2014-01-01

    Several etiological factors for gingival recession have been discussed in the literature, and the vestibular region of the mandibular incisors is a critical anatomical area for the emergence of this condition. Anterior crossbite is an important factor, because the trauma from occlusion between the incisors generates an imbalance in the distribution of forces, causing changes in the periodontium and making the area more susceptible to mechanical trauma during brushing and to plaque formation. ...

  11. [3 cases of gingival hyperplasia during nifedipine therapy].

    Science.gov (United States)

    Doria, G; Cangemi, F; Gulizia, M; Lo Giudice, P; Circo, A

    1990-03-01

    The authors report the cases of three male patients, aged 36, 54 and 52 years, who developed gingival hypertrophy during treatment with nifedipine at a dose of 40 mg/daily. Hypertrophy was the same as that observed in patients treated with anti-convulsive or cytostatic drugs, and may probably be due to interference with calcium ions and local factors. Full recovery was achieved by suspending nifedipine treatment in all patients.

  12. Playful strategies that increase the knowledge of students on gingivitis

    OpenAIRE

    Melissa Katherine Sánchez-Peña; Kelly Johana Sánchez-Delgado; Alexandra Agudelo-Ramírez

    2015-01-01

    The purpose of this research was to formulate and implement playful strategies to increase the level of knowledge in a group of students about gingivitis associated with bacterial plaque and its prevention, this project was developed in Pereira city at Alfonso Jaramillo Gutiérrez high school. The studio started from assuming that traditional teaching methodologies have proved to be highly ineffective and considering that playful strategies strengthen the active participation of the subject co...

  13. The Effect of Cigarette Smoking on Gingival Crevicular Fluid Flow.

    Science.gov (United States)

    1986-01-01

    ninhydrin and examined under magnification . Scatter diagrams indicated a poor correlation between the Gingival Exudate Index and all other indices...the sample, and the stained area was measured under high power magnification . 8 6 8 8 ,98 ,9 9 In recent years a device called the Periotron (Harco...Dental Officer McGuire Air Force Base, New Jersey February 1977 to July 1981 Base Dental Officer Chief, Restorative Dentistry Chief, Endodontics JEielson

  14. Treatment of Gingival Hyperpigmentation by Diode Laser for Esthetical Purposes

    Directory of Open Access Journals (Sweden)

    Hanaa M. El Shenawy

    2015-08-01

    Full Text Available BACKGROUND: Gingival hyperpigmentation is a common esthetical concern in patients with gummy smile or excessive gingival display. Laser ablation has been recognized recently as the most effective, pleasant and reliable technique. It has the advantage of easy handling, short treatment time, hemostasis, decontamination, and sterilization effect. AIM: In the present study we wanted to explore the efficacy of a 980 nm wavelength diode laser in gingival depigmentation clinically by using both VAS and digital imaging method as means of assessment. METHODS: Diode laser ablation was done for 15 patients who requested cosmetic therapy for melanin pigmented gums. The laser beam delivered by fiberoptic with a diameter of 320 µm, the diode laser system has 980 nm wave lengths and 3 W irradiation powers, in a continuous contact mode in all cases, the entire surface of each pigmented maxillary and mandibular gingiva that required treatment was irradiated in a single session. Clinical examination and digital image analysis were done and the patients were followed up for 3 successive months. RESULTS: There was a statistically significant change in prevalence of bleeding after treatment, as none of the cases showed any signs of bleeding 1 week, 1 month and 3 months after ablation. No statistically significant change was observed in the prevalence of swelling after treatment The VAS evaluation demonstrated that only 4 patients complained of mild pain immediately after the procedure. No pain was perceived from the patients in the rest of the follow up period. There was no statistically significant change in prevalence of pain immediately after treatment compared to pain during treatment. There was a decrease in cases with mild pain after 1 week, 1 month as well as 3 months compared to pain during treatment and immediately after treatment. CONCLUSION: Within the limitations of this study, the use of diode laser was shown to be a safe and effective treatment

  15. Treatment of Gingival Hyperpigmentation by Diode Laser for Esthetical Purposes.

    Science.gov (United States)

    El Shenawy, Hanaa M; Nasry, Sherine A; Zaky, Ahmed A; Quriba, Mohamed A A

    2015-09-15

    Gingival hyperpigmentation is a common esthetical concern in patients with gummy smile or excessive gingival display. Laser ablation has been recognized recently as the most effective, pleasant and reliable technique. It has the advantage of easy handling, short treatment time, hemostasis, decontamination, and sterilization effect. In the present study we wanted to explore the efficacy of a 980 nm wavelength diode laser in gingival depigmentation clinically by using both VAS and digital imaging method as means of assessment. Diode laser ablation was done for 15 patients who requested cosmetic therapy for melanin pigmented gums. The laser beam delivered by fiberoptic with a diameter of 320 µm, the diode laser system has 980 nm wave lengths and 3 W irradiation powers, in a continuous contact mode in all cases, the entire surface of each pigmented maxillary and mandibular gingiva that required treatment was irradiated in a single session. Clinical examination and digital image analysis were done and the patients were followed up for 3 successive months. There was a statistically significant change in prevalence of bleeding after treatment, as none of the cases showed any signs of bleeding 1 week, 1 month and 3 months after ablation. No statistically significant change was observed in the prevalence of swelling after treatment The VAS evaluation demonstrated that only 4 patients complained of mild pain immediately after the procedure. No pain was perceived from the patients in the rest of the follow up period. There was no statistically significant change in prevalence of pain immediately after treatment compared to pain during treatment. There was a decrease in cases with mild pain after 1 week, 1 month as well as 3 months compared to pain during treatment and immediately after treatment. Within the limitations of this study, the use of diode laser was shown to be a safe and effective treatment modality that provides optimal aesthetics with minimal discomfort in

  16. Pink esthetics in periodontics - Gingival depigmentation: A case series

    OpenAIRE

    Arthiie Thangavelu; Sugumari Elavarasu; Piranitha Jayapalan

    2012-01-01

    Smile expresses a feeling of joy, success, sensuality, affection, and courtesy, and reveals self-confidence and kindness. The harmony of the smile is determined not only by the shape, the position, and the color of the teeth, but also by the gingival tissues. Although melanin pigmentation of the gingiva is completely benign and does not present a medical problem, complaints of “black gums” are common, particularly in patients having a very high smile line. Thus, perio-esthetic treatment modal...

  17. Aesthetic Depigmentation of Gingival Smoker's Melanosis Using Carbon Dioxide Lasers

    OpenAIRE

    Luis Silva Monteiro; José Adriano Costa; Marco Infante da Câmara; Rui Albuquerque; Marco Martins; José Júlio Pacheco; Filomena Salazar; Fernando Figueira

    2015-01-01

    Melanic pigmentation results from melanin produced by the melanocytes present in the basal layer of the oral epithelium. One of the most common causes of oral pigmentation is smoker melanosis, a condition associated with the melanocyte stimulation caused by cigarette smoke. This paper aims to illustrate the use of a carbon dioxide laser in the removal of the gingival melanic pigmentation for aesthetic reasons in a 27-year-old female patient with history of a smoking habit. The carbon dioxide ...

  18. Gingival hypertrophy in a child: Expect the unexpected

    OpenAIRE

    Ravikumar, Rekha; Manohar, Rakesh; Latha, Sneha Magatha; Scott, Julius Xavier

    2016-01-01

    Acute leukemia is the most common malignant disorder of childhood. Acute leukemia is characterized by marrow failure due to the replacement of marrow elements by leukemic blasts. Gingival hypertrophy (GH) due to acute myeloid leukemia (AML) in a child is extremely rare. Here, we report a case of AML (subtype M5 of FAB classification) in a 3-year-old male child wherein the disease primarily presented as GH.

  19. Restauración del tejido gingival a partir de fibroblastos autólogos

    Directory of Open Access Journals (Sweden)

    Eduvigis Solórzano N

    2013-12-01

    Full Text Available El interés de la investigación básica biomédica ha tenido un crecimiento vertiginoso en los últimos años y la odontología no escapa a esta motivación, es así como estamos en la búsqueda de alternativas de tratamiento a defectos de tejidos blandos y óseos que permitan resultados satisfactorios a nuestros pacientes desde el punto de vista estético y funcional, ya que en ocasiones, las limitaciones en la cantidad de tejido disponible para autoinjerto no permiten el éxito esperado, es por ello que la interdisciplinariedad ha permitido la exploración de nuevas fuentes de tejido bucal. Las investigaciones actuales se enfocan en el desarrollo y caracterización de tejidos equivalentes a la mucosa bucal y se ha demostrado que los fibroblastos del conectivo gingival participan eficientemente en la reparación de los tejidos, razón por la cual se están utilizando con mucho éxito en medicina regenerativa; así como también el aislamiento de células progenitoras mesenquimáticas a partir de diversos tejidos bucales, entre ellos el más utilizado, la pulpa dental.

  20. Efficacy of triphala mouth rinse (aqueous extracts) on dental plaque and gingivitis in children.

    Science.gov (United States)

    Bhattacharjee, Ritesh; Nekkanti, Sridhar; Kumar, Nikesh G; Kapuria, Ketan; Acharya, Shashidhar; Pentapati, Kalyana C

    2015-08-01

    The aim of the present study was to evaluate the efficacy of triphala mouth rinse (aqueous) in the reduction of plaque and gingivitis among children. The study was a randomized, double-blinded, controlled trial, with a total of 60 school children (n = 30 in each group; triphala and chlorhexidine groups). Plaque and gingival indices were used to evaluate baseline and follow-up plaque and gingivitis. A total of 57 children completed the study. Both chlorhexidine and triphala groups showed significantly lower mean gingival and plaque index scores at follow up than baseline (P plaque index was significantly higher in the chlorhexidine group compared to the triphala group (P = 0.048). The effectiveness of triphala in the reduction of plaque and gingivitis was comparable to chlorhexidine, and can be used for short-term purposes without potential side-effects. It is a cost-effective alternative in reducing plaque and gingivitis. © 2014 Wiley Publishing Asia Pty Ltd.

  1. A Rare Case Report of Amlodipine-Induced Gingival Enlargement and Review of Its Pathogenesis

    Directory of Open Access Journals (Sweden)

    Sanjeev Joshi

    2013-01-01

    Full Text Available Gingival enlargement is a common clinical feature of gingival and periodontal diseases. It is an unwanted side effect of certain systemic drugs given for nondental treatment. It is being reported with three main groups of drugs like calcium channel blockers (CCBs, immunosuppressants, and anticonvulsants. Among calcium channel blockers, nifedipine causes gingival hyperplasia in about 10% of patients, whereas the incidence of amlodipine-, a third generation calcium channel blocker, induced gingival hyperplasia is very limited. There are very few reports of amlodipine-induced gingival enlargement at a dose of 5 mg. We report a case of amlodipine-induced gingival enlargement in a 45-year-old hypertensive patient taking amlodipine at a dose of 5 mg.

  2. Incidence of amlodipine-induced gingival overgrowth in the rural population of Loni

    Directory of Open Access Journals (Sweden)

    Avneesh Tejnani

    2014-01-01

    Full Text Available Aims: Since the incidence of gingival overgrowth induced by amlodipine remains poorly defined, this study was carried out with an aim to determine the incidence. Materials and Methods: Dental patients who received amlodipine (N = 115, for more than 3 months were studied to determine the drug-induced gingival overgrowth. Clinical diagnosis of drug-induced overgrowth was verified by disappearance or decreased severity of gingival overgrowth after withdrawal of the causative drug. Results: The prevalence rate of amlodipine-induced gingival hyperplasia among experimental patients was 3.4%, while it was not observed among the control subjects. Oral examination revealed gingival overgrowth as a lobular or nodular enlargement on interdental papilla located in the anterior interproximal regions. Conclusions: In this study, there was a significant relationship between gingival inflammation resulting from dental plaque and drug dosage, and hyperplasia.

  3. Clinical diagnosis and treatment of necrotizing ulcerative gingivitis in the orthodontic patient. A case report.

    Directory of Open Access Journals (Sweden)

    Jesús Rodríguez-Pulido

    2016-04-01

    Full Text Available Introduction: About 0.1% of the population suffers from necrotizing ulcerative gingivitis, a disease of rapid progression and acute manifestation, which may progress to necrotizing ulcerative periodontitis and eventually to bone sequestration and loss of gingival tissue. Case report: A 21-year-old female patient undergoing orthodontic treatment for six months, diagnosed with necrotizing ulcerative gingivitis due to acute pain in the gingival tissue, spontaneous bleeding, halitosis and abundant plaque. The treatment was conservative and effective, obtaining total remission of the lesion after seven days and three months of postoperative follow-up. Conclusion: Today there are no epidemiological or clinical reports that support the relationship of necrotizing ulcerative gingivitis and orthodontic treatment. Prevention is critical to the success of the treatment, which is why the dentist should recognize the clinical features of necrotizing ulcerative gingivitis to raise awareness of its risks in the orthodontic patient.

  4. Interrelationship of intelligence quotient with caries and gingivitis.

    Science.gov (United States)

    Navit, Saumya; Malhotra, Garima; Singh, Jashina; Naresh, V; Anshul; Navit, Pragati

    2014-07-01

    Intelligence is the property of mind that encompasses many related abilities, such as the capacities to reason, plan, solve the problem, think, comprehend ideas, use languages and to learn. Intellectual level of a person influence the abilities to learn from experience, adapt to new situations, understand and handle abstract concepts, and use knowledge to manipulate one's environment. This abstract thinking helps the child to maintain his/her oral hygiene in a better way. The present study was carried out on 252 children of 10-15 years old, reported to the out-patient Department of Pedodontics and Preventive Dentistry; of Teerthanker Mahaveer Dental College and Research Centre; Moradabad, in order to assess the relation between IQ of a child with dental caries and gingival disease. The statistical analysis was performed using Statistical Package for Social Sciences Version 15.0 statistical analysis software. Statistically, there was a significant difference among different intelligence groups and the prevalence of moderate gingivitis (P intelligence (90.9%), and no significant association between level of intelligence and caries prevalence was observed (P = 0.572). There was a statistical significant relation between IQ and prevalence of moderate gingivitis and no significant relationship was observed between IQ and dental caries.

  5. Dual lifestyle of Porphyromonas gingivalis in biofilm and gingival cells.

    Science.gov (United States)

    Sakanaka, Akito; Takeuchi, Hiroki; Kuboniwa, Masae; Amano, Atsuo

    2016-05-01

    Porphyromonas gingivalis is deeply involved in the pathogenesis of marginal periodontitis, and recent findings have consolidated its role as an important and unique pathogen. This bacterium has a unique dual lifestyle in periodontal sites including subgingival dental plaque (biofilm) and gingival cells, as it has been clearly shown that P. gingivalis is able to exert virulence using completely different tactics in each environment. Inter-bacterial cross-feeding enhances the virulence of periodontal microflora, and such metabolic and adhesive interplay creates a supportive environment for P. gingivalis and other species. Human oral epithelial cells harbor a large intracellular bacterial load, resembling the polymicrobial nature of periodontal biofilm. P. gingivalis can enter gingival epithelial cells and pass through the epithelial barrier into deeper tissues. Subsequently, from its intracellular position, the pathogen exploits cellular recycling pathways to exit invaded cells, by which it is able to control its population in infected tissues, allowing for persistent infection in gingival tissues. Here, we outline the dual lifestyle of P. gingivalis in subgingival areas and its effects on the pathogenesis of periodontitis. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. Case report: aesthetic management of a localised periodontal defect with a gingival veneer prosthesis.

    Science.gov (United States)

    Ellis, S G; Sharma, P; Harris, I R

    2000-03-01

    Traditionally acrylic resin gingival veneer prostheses have been used to disguise aesthetic deficiencies of maxillary anterior teeth following successful periodontal therapy and have been retained by engaging horizontal undercuts distal to the canine teeth. They are, however, versatile prostheses with uses in fixed and removable prosthodontics and therapeutic treatment of gingival conditions. In the case presented a small acrylic resin gingival veneer prosthesis retained by a resilient lining material was used to manage a localised periodontal defect of the mandibular central incisor teeth.

  7. Plasma cell gingivitis - A rare case related to Colocasia (arbi leaves

    Directory of Open Access Journals (Sweden)

    Deepika Bali

    2012-01-01

    Full Text Available Plasma cell gingivitis is an uncommon inflammatory condition of uncertain etiology often flavoured chewing gum, spices, foods, candies, or dentifrices. The diagnosis of plasma cell gingivitis is based on comprehensive history taking, clinical examination, and appropriate diagnostic tests. Here we are presenting a rare case of plasma cell gingivitis caused by consumption of colocasia (arbi leaves. Colocasia is a kind of vegetable, very commonly consumed in the regions of North India.

  8. Gingival depigmentation: A split mouth comparative study between scalpel and cryosurgery

    Directory of Open Access Journals (Sweden)

    Kaustubh P Patil

    2015-01-01

    Full Text Available Gingival hyperpigmentation is a major esthetic concern for many people. Although it is not a medical problem, many people complain of dark gums as unesthetic. Gingival depigmentation is a periodontal plastic surgical procedure, whereby the hyperpigmentation is removed or reduced by various techniques. For depigmentation of gingival, different treatment modalities have been reported, such as scalpel, cryosurgery, electrosurgery, lasers, etc., this article compares the management of three cases with scalpel and cryosurgery and also highlights the relevance of cryosurgery.

  9. Candida spp. and gingivitis in children with nephrotic syndrome or type 1 diabetes

    OpenAIRE

    Olczak-Kowalczyk, Dorota; Pyr?ak, Beata; D?bkowska, Maria; Pa?czyk-Tomaszewska, Ma?gorzata; Miszkurka, Gra?yna; Rogozi?ska, Izabela; Swoboda-Kope?, Ewa; GOZDOWSKI, Dariusz; Kali?ska, Angelika; Pir?g, Anna; Mizerska-Wasiak, Ma?gorzata; Roszkowska-Blaim, Maria

    2015-01-01

    Background Diabetes and Nephrotic syndrome (NS) promote plaque-related gingivitis and yeast-like fungal infections. The study assesses the impact of Candida spp. and general disease- or treatment-related factors on plaque-related gingivitis severity in children and adolescents with Nephrotic syndrome /diabetes. Methods Body mass index (BMI), BMI standard deviation score, and oral cavity (Plaque Index ? PLI,?Gingival Index ? GI, mucosa status, presence and Candida enzymatic activity) were asse...

  10. Scalpel Depigmentation and Surgical Crown Lengthening to Improve Anterior Gingival Esthetics

    OpenAIRE

    Chethana, KC; Pradeep, K.

    2016-01-01

    A smile is a mesmerizing expression of joy, success, courtesy and reveals self-confidence. The harmony of the smile is determined not only by the shape, position and the color of teeth, but also by the gingival architecture. Gingival tissues form an important part of what we can consider to be a pleasing smile. The elegance of this pleasant smile could be, affected by highly pigmented gingiva. This gingival pigmentation occurs as a result of melanin granules, which are produced by melanoblast...

  11. Gingival depigmentation: A split mouth comparative study between scalpel and cryosurgery

    OpenAIRE

    Patil, Kaustubh P.; Vaibhav Joshi; Vijay Waghmode; Vinayak Kanakdande

    2015-01-01

    Gingival hyperpigmentation is a major esthetic concern for many people. Although it is not a medical problem, many people complain of dark gums as unesthetic. Gingival depigmentation is a periodontal plastic surgical procedure, whereby the hyperpigmentation is removed or reduced by various techniques. For depigmentation of gingival, different treatment modalities have been reported, such as scalpel, cryosurgery, electrosurgery, lasers, etc., this article compares the management of three cases...

  12. Gingival depigmentation: A split mouth comparative study between scalpel and cryosurgery.

    Science.gov (United States)

    Patil, Kaustubh P; Joshi, Vaibhav; Waghmode, Vijay; Kanakdande, Vinayak

    2015-03-01

    Gingival hyperpigmentation is a major esthetic concern for many people. Although it is not a medical problem, many people complain of dark gums as unesthetic. Gingival depigmentation is a periodontal plastic surgical procedure, whereby the hyperpigmentation is removed or reduced by various techniques. For depigmentation of gingival, different treatment modalities have been reported, such as scalpel, cryosurgery, electrosurgery, lasers, etc., this article compares the management of three cases with scalpel and cryosurgery and also highlights the relevance of cryosurgery.

  13. Aetiology and severity of gingival recession in an adult population sample in Greece

    Directory of Open Access Journals (Sweden)

    Nikolaos Andreas Chrysanthakopoulos

    2011-01-01

    Full Text Available Background: Gingival recession is the most common and undesirable condition of the gingiva. The aim of study was to investigate the aetiology and severity of gingival recession in a Greek adult population sample. Methods : The study was performed on 165 males and 179 females, 18-68 years old who sought dental treatment in a private dental practice and showed gingival recession. All subjects were clinically examined and answered questions regarding their oral hygiene habits such as the type of toothbrush, frequency of brushing and method of brushing. The association between gingival recession and the following parameters was assessed: plaque score, gingival score and tooth position. Statistical analysis of the results was accomplished using chi-square test (α = 0.05. Results: The majority (79.4% of the patients showed grade I gingival recession and 15.3% showed grade II gingival recession. The maxillary 1 st and 2 nd molars (35.3% and the mandibular 1 st and 2 nd molars (28.7% were the teeth most frequently affected by root surface exposure. Patients with sub-gingival calculus, bacterial plaque and gingival inflammation (P < 0.05, malpositioned teeth (P < 0.001, horizontal brushing method, medium type of toothbrush (P < 0.001 and brushing once daily (P < 0.001 appeared to be the most common precipitating aetiological factor for gingival recession. Conclusion: According to the results of the present study, gingival recession was the result of more than one factor acting together. Horizontal brushing method, usage of medium type toothbrush and tooth brushing once daily were found to be more associated with gingival recession.

  14. Hyperthermia and massage are effect for the gingivitis improvement; Onnetsu to massaji ga shinikuen kaizen ni koka

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-10-01

    It was confirmed that Kao and research group of Nosaka professor of Iwate Medical Univ. faculty of dentistry that hyperthermia and massage at the 40 degrees C for the gingival activate the gingival lymph duct function and that it improves the gingivitis was effective. By causing the microcirculation disorder of the gingival, the research of the vascularisation is main until now for the gingivitis. Present research demonstrated that the recovery of the lymph duct function was effective for the gingivitis improvement for the first time in the world. (translated by NEDO)

  15. REDUCTION OF MOBILITY OF PERIODONTALY AFFECTED TEETH AFTER GINGIVAL AUGMENTATION WITH AN AUTOGENOUS GINGIVAL GRAFT (Case Report.

    Directory of Open Access Journals (Sweden)

    Kamen Kotsilkov

    2015-02-01

    Full Text Available INTRODUCTION: The most severe complication of advanced periodontal lesions is the loss of teeth due to terminal attachment loss and high grade mobility. The goals of the treatment are the improving the plaque control stabilizing of the mobile teeth and arresting of the progression of gingival recession achieving gingival augmentation with adequate vestibulum depth. The autogenous graft is considered to be the most efficient approach where a significant increase of the attached gingiva is needed. OBJECTIVE: This presentation demonstrates the capacity of the autogenous gingival graft approach to reduce the high grade tooth mobility and to augment keratinized gingiva. METHODS: V.T. (46 with moderate generalized periodontitis. The examination reveals thin periodontal biotype, Class IV recessions on 31,41 with III grade mobility and terminal attachment loss, narrow vestibulum and lack of attached gingiva. An autogenous graft technique was selected to achieve simultaneous gingival augmentation and correction of vestibulum depth. RESULTS: A significant and stable increase of the attached gingiva is observed which led to better access for oral hygiene thus creating better conditions for successful long-term outcome. The root coverage was more that 40% and the tooth mobility was decreased to grade I. CONCLUSION: In the limitations of the presented case the free autogenous graft technique seems an appropriate approach in cases with deep Class IV recessions and high grade toot mobility in mandibular frontal area creating proper conditions for effective oral hygiene and decreasing tooth mobility by creating a sufficient amount of attached gingiva needed for the long term maintenance.

  16. Immunoexpression of α2-integrin and Hsp47 in hereditary gingival fibromatosis and gingival fibromatosis-associated dental abnormalities

    Science.gov (United States)

    de Oliveira-Santos, Carolina; Della-Coletta, Ricardo; Cristianismo-Costa, Daiane; Paranaíba, Lívia M.-R.; Martelli-Júnior, Hercílio

    2013-01-01

    Objective: The purpose of the present study was to investigate the expression of the α2-integrin subunit and heat shock protein 47 (Hsp47) in two families with isolated gingival fibromatosis (GF) form and one family with GF associated with dental abnormalities and normal gingiva (NG). Study Design: Immunohistochemistry was performed with antibodies against α2-integrin and Hsp47 in specimens from two unrelated families with hereditary gingival fibromatosis (Families 1 and 2) and from one family with a gingival fibromatosis-associated dental abnormality (Family 3); NG samples were used for comparison. The results were analysed statistically. Results: Immunoreactivity for α2-integrin and Hsp47 was observed in the nucleus of epithelial cells of both the basal and suprabasal layer and a more discreet signal was noted in connective tissue in all study samples. Hsp47 showed higher immunoreactivity in Family 2 compared with the other families (p≤0.05). Despite the markup α2-integrin was higher in Family 3 there was no statistically significant difference between the families studied (p≥0.05). Conclusions: Our results confirmed the heterogeneity of GF, such that similar patterns of expression of the condition may show differences in the expression of proteins such as Hsp47. Although no difference in α2-integrin expression was observed between GF and NG groups, future studies are necessary to determine the exact role of this protein in the various forms of GF and whether it contributes to GF pathogenesis. Key words:Gingival fibromatosis, integrin alpha2, heat shock protein Hsp47. PMID:23229240

  17. Prevention and treatment of chronic catarrhal gingivitis and gingival recession in patients with non-removable dental prosthesis designs

    Directory of Open Access Journals (Sweden)

    Анатолій Михайлович Петрушанко

    2015-05-01

    Full Text Available Schemes of prevention and treatment of chronic catarrhal gingivitis and gingival recession in patients with non-removable dental prosthesis designs. It is proved their clinical effectiveness and evaluation criteria of developed gum recession land. After application of preventive and therapeutic complexes, which observed in patients, improve the hygienic condition of the mouth, confirming the feasibility of their application.Methods. It is included 153 patients with various defects of individual teeth and dentition, including 85 women (55.6% and 68 men (44.4% aged from 25 to 55 years. The control group consisted of 35 healthy individuals of the same age without metallic inclusions in the mouth.Results. In analyzing the evaluation index hygienic condition of the oral cavity in patients 25-34 years of gingivitis against the backdrop of orthopedic treatment non-removable denture constructions the indices Green-Vermillion and Silness-Loe following data were obtained: patients of the main group before treatment, the rate Green Vermillion index was an average of 1,70 ± 0,07 points to 1,75 ± 0,08 points, indicating a satisfactory level of oral hygiene. After application of preventive and therapeutic complexes improve the hygienic condition of the oral cavity, which marked the studied index indicators hygiene.Analyzing the data should be noted that positive changes of hygienic condition of the oral cavity were observed throughout the study period in all age groups of patients in both subgroups of observation and comparison.Conclusions. We offer health care systems for the prevention and treatment of gum recession and chronic catarrhal gingivitis in patients after dental prosthetics of non-replaceable constructs allowed to suspend pathological processes in the gums and improve oral hygiene

  18. Gingival recession following apical surgery in the esthetic zone: a clinical study with 70 cases

    DEFF Research Database (Denmark)

    von Arx, Thomas; Salvi, Giovanni E; Janner, Simone

    2009-01-01

    margin. Changes in GM and CAL were then correlated with patient-, tooth-, and surgery-related parameters. The following parameters were found to significantly influence changes in GM and CAL over time: gingival biotype (P biotype exhibiting more gingival recession than thick biotype...... incision, papilla-base incision or papilla-saving incision. The visual assessment using pre-treatment and 1-year follow-up photographs did not demonstrate significant changes in gingival level or papillary height after apical surgery. In conclusion, gingival biotype, pre-treatment PPD, and type of incision...

  19. Association of gingival biotype with the results of scaling and root planing.

    Science.gov (United States)

    Sin, Yeon-Woo; Chang, Hee-Yung; Yun, Woo-Hyuk; Jeong, Seong-Nyum; Pi, Sung-Hee; You, Hyung-Keun

    2013-12-01

    The concept of gingival biotype has been used as a predictor of periodontal therapy outcomes since the 1980s. In the present study, prospective and controlled experiments were performed to compare periodontal pocket depth (PPD) reduction and gingival shrinkage (GSH) after scaling and root planing (SRP) according to gingival biotype. Twenty-five patients diagnosed with chronic periodontitis participated in the present study. The PPD and GSH of the labial side of the maxillary anterior teeth (from the right canine to the left canine) were evaluated at baseline and 3 months after SRP. Changes in the PPD following SRP were classified into 4 groups according to the gingival thickness and initial PPD. Two more groups representing normal gingival crevices were added in evaluation of the GSH. The results were statistically analyzed using the independent t-test. In the end, 16 patients participated in the present study. With regard to PPD reduction, there were no significant differences according to gingival biotype (P>0.05). Likewise, sites with a PPD of over 3 mm failed to show any significant differences in the GSH (P>0.05). However, among the sites with a PPD of under 3 mm, those with the thin gingival biotype showed more GSH (Pbiotype with either shallow or deep periodontal pockets. GSH also showed equal outcomes in all the groups without normal gingival crevices. The results of SRP seem not to differ according to gingival biotype.

  20. Esthetic impact of gingival plastic surgery from the dentistry students' perspective.

    Science.gov (United States)

    Ayyildiz, Erdem; Tan, Enes; Keklik, Hakan; Demirtag, Zulfikar; Celebi, Ahmet Arif; Pithon, Matheus Melo

    2016-01-01

    The aim of the this study was to evaluate the perception of smile esthetics and alterations in cases of gingival plastic surgery for correction of a gummy smile, by means of alterations in smile photograph among dentistry degree students. A frontal smile photograph of a 40-year-old woman having normal occlusion was used with diverse compositions of gingival exposure level and crown length of maxillary teeth. The eight photographs were evaluated by 216 dentistry students in five class groups (1(st), 2(nd), 3(rd), 4(th) and 5(th) classes). The results revealed that almost all of the class' students perceived differences between images, additionally, the highest percentage of students that answered "no difference" was 12% at 1(st) class' students. 1(st) and 2(nd) class' students most liked photograph which is 2.5 mm gingival display and 3(rd) class students liked two different photographs which are 2.5 mm gingival display and 2 mm gingival display whereas 4(th) class students preferred two different photographs which are 1.5 mm gingival display and 1 mm gingival display, 5(th) class students preferred photograph which is 1.5 mm gingival display as the most. Esthetic perception of smile improve as a student passes to higher study classes in terms of gingival exposure. The harmonious display of gingiva exhibits an important effect in the smile esthetics rather than reduced or excessive display.

  1. Development of labial gingival recessions in orthodontically treated patients.

    Science.gov (United States)

    Renkema, Anne Marie; Fudalej, Piotr S; Renkema, Alianne; Kiekens, Rosemie; Katsaros, Christos

    2013-02-01

    Our aim was to assess the prevalence of gingival recessions in patients before, immediately after, and 2 and 5 years after orthodontic treatment. Labial gingival recessions in all teeth were scored (yes or no) by 2 raters on initial, end-of-treatment, and posttreatment (2 and 5 years) plaster models of 302 orthodontic patients (38.7% male; 61.3% female) selected from a posttreatment archive. Their mean ages were 13.6 years (SD, 3.6; range, 9.5-32.7 years) at the initial assessment, 16.2 years (SD, 3.5; range, 11.7-35.1 years) at the end of treatment, 18.6 years (SD, 3.6; range, 13.7-37.2 years) at 2 years posttreatment, and 21.6 (SD, 3.5; range, 16.6-40.2 years) at 5 years posttreatment. A recession was noted (scored "yes") if the labial cementoenamel junction was exposed. All patients had a fixed retainer bonded to either the mandibular canines only (type I) or all 6 mandibular front teeth (type II). There was a continuous increase in gingival recessions after treatment from 7% at end of treatment to 20% at 2 years posttreatment and to 38% at 5 years posttreatment. Patients less than 16 years of age at the end of treatment were less likely to develop recessions than patients more than 16 years at the end of treatment (P = 0.013). The prevalence of recessions was not associated with sex (P = 0.462) or extraction treatment (P = 0.32). The type of fixed retainer did not influence the development of recessions in the mandibular front region (P = 0.231). The prevalence of gingival recessions steadily increases after orthodontic treatment. The recessions are more prevalent in older than in younger patients. No variable, except for age at the end of treatment, seems to be associated with the development of gingival recessions. Copyright © 2013 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  2. Distribution of dental plaque and gingivitis within the dental arches.

    Science.gov (United States)

    Sreenivasan, Prem K; Prasad, Kakarla V V

    2017-10-01

    Objective The natural accumulation of supragingival plaque on surfaces of human teeth is associated with gingival inflammation and the initiation of common oral diseases. This study evaluated the distribution of dental plaque and gingivitis scores within the dental arches after prophylaxis. Methods Adult subjects from the Dharwad, India area representing the general population who provided written informed consent were scheduled for screening. Healthy subjects over the age of 18 years, not currently requiring any medical or dental care, and presenting with a complement of at least 20 natural teeth were recruited for this parallel design study. Enrolled subjects (n = 41) underwent oral examinations for dental plaque (PI) and gingivitis (GI) using the Turesky modification of the Quigley-Hein and the Löe-Silness Index, respectively, at the baseline visit, followed by a whole mouth dental prophylaxis. Subjects were given fluoride toothpaste for twice daily oral hygiene for the next 30 days. Subjects were recalled on days 15 and 30 for PI and GI examinations identical to baseline. Results Analyses indicated that mean scores for PI and GI on either arch and the whole mouth were higher than 2 and 1, respectively, during all examinations. Anterior surfaces consistently exhibited lower PI scores than posterior regions of either arch, or the entire dentition. Regional GI differences within the dentition were similar to PI scores, with lower scores on anterior than posterior teeth. Prophylaxis reduced both the frequency and mean scores of both PI and GI, irrespective of arch, with lower scores observed on anterior than posterior regions during all recall visits. Molar and lingual regions consistently exhibited higher PI and GI scores compared with anterior surfaces. At all examinations, mean scores for both plaque and gingivitis were higher on approximal vestibular than mid-vestibular surfaces. Conclusions Differences observed in PI and GI within the dentition have

  3. Efficacy of collagen membrane seeded with autologous gingival fibroblasts in gingival recession treatment: a randomized, controlled pilot study.

    Science.gov (United States)

    Köseoğlu, Serhat; Duran, İsmet; Sağlam, Mehmet; Bozkurt, S Buket; Kırtıloğlu, Osman S; Hakkı, Sema S

    2013-10-01

    Gingival recession (GR) is one of the most common esthetic concerns associated with periodontal tissues. Recently, tissue engineering technology has been developed and applied in periodontology for the treatment of GR. The aim of this study is to compare the clinical efficacy of collagen membrane with or without autologous gingival fibroblasts under a coronally advanced flap for root coverage. In this split-mouth, controlled clinical study, 22 sites are selected from 11 patients with Miller Class I recessions affecting canines or premolars in the maxillary arch. One tooth in each patient was randomized to receive either a collagen membrane (CM) (control group) or a collagen membrane seeded with autologous gingival fibroblasts (CM+GF) (test group) under a coronally advanced flap. Thickness of the gingiva, GR, and percentage of root coverage (PRC) were recorded by a calibrated examiner at baseline and 3, 6, and 12 months postoperatively. Furthermore, GR and PRC were evaluated using photogrammetric analysis at baseline and 3, 6, and 12 months. Both treatments resulted in a significant gain in root coverage compared with baseline. A statistically significant increase was detected in PRC in the test group compared with the control group. No significant difference was noted between the test and control sites regarding the thickness of the gingiva. The results indicated that CM+GF prepared by tissue engineering technology can be considered an alternative method for the treatment of Miller Class I recession defects.

  4. Respuesta citológica exfoliativa gingival en diferentes técnicas de tratamiento periodontal

    Directory of Open Access Journals (Sweden)

    Nereyda Riesgo Lobaina

    1996-08-01

    Full Text Available Se realizó una investigación con el propósito de identificar los patrones de exfoliación celular durante la evolución del tratamiento periodontal y comparar la respuesta citológica gingival en diversos métodos terapéuticos. Se estudiaron 90 pacientes de uno y otro sexos en edades comprendidas entre los 20 y 50 años. Se formaron 3 grupos de 30 pacientes, en cada uno se tuvo en cuenta que la enfermedad clínica fuera electiva de alguna de las modalidades de tratamiento previstas en el estudio (colgajo, gingiventomía, raspado y alisado radicular. Las muestras citológicas se tomaron en la zona vestibular de las encías marginal y papilar mediante raspado; se fijaron por rocío químico (cytospray y se colorearon con el método clásico de Shorr-Pundel. La evaluación celular se realizó considerando sólo 2 tipos citológicos: células superficiales sin núcleo (ST2 y células superficiales con núcleos (ST1. En cada preparación microscópica se contaron aleatoriamente 300 células. Para evaluar el grado de queratinización de la encía se utilizó el índice de queratinización. Se realizó un seguimiento citológico periódico en 4 etapas: antes del tratamiento, al finalizar la preparación inicial y después de 15 y 45 días de tratamiento. Se comprobó que la encía recupera su patrón citológico normal a los 45 días.This investigation was performed with the aim of identifiing the patterns of cell exfoliation during the course of periodontal treatment, and comparing the gingival cytologic response with different therapeutical methods. A number of 90 patients of both sexes with ages ranging from 20 to 50 years studied. Three groups with 30 patients each were formed taking into account that they presented with clinical disease elective for certain therapeutical modalities established in the study (flaps, gingivectomy, dental scaling, and root planing. Cytologic samples were taken in the vestibular zone of the marginal and papillar

  5. Effectiveness of Cryogen Tetrfluoroethane on Elimination of Gingival Epithelium and its Clinical Application in Gingival Depigmentation–Histological Findings and Case Series

    Science.gov (United States)

    Kumar, Santhosh; Bhat, G. Subraya; Bhat, K. Mahalinga

    2013-01-01

    Objective: To histologically assess and clinically co-relate the effectiveness of cryogen Tetrafluoroethane (TFE) for gingival depigmentation procedure. Material and Methods: Twelve patients having unaesthetic gingival melanin pigmentation were included in the study. Gingival tissues of eight patients having gingival melanin pigmentation undergoing gingivoplasty or gingivectomy for crownlengthening were exposed to the cryogen and this was used for the histological examination. Gingivectomies were done after 8, 24, 96 hours and after a week of application of tetrafluoroethane. Four fair skinned patients complaining of unaesthetic gingival hyperpigmentation underwent gingival depigmentation using Tetrafluoroethane cryogen. Results: Histologically after 96 hours of application of cryogen there was complete loss of retepegs and epithelial detachment from the corium was evident. Complete re – epithelialisation was noted after a week and was clinically correlated. Conclusion: We therefore, concluded that histologically tetrafluoroethane can effectively destroy gingival epithelium without causing damage to the connective tissue and clinically the color of the gingiva had more pleasing appearance 6 months postoperatively. Hence the cryogen can be used safely for depigmentation procedure. PMID:24551730

  6. Effectiveness of cryogen tetrfluoroethane on elimination of gingival epithelium and its clinical application in gingival depigmentation-histological findings and case series.

    Science.gov (United States)

    Kumar, Santhosh; Bhat, G Subraya; Bhat, K Mahalinga

    2013-12-01

    To histologically assess and clinically co-relate the effectiveness of cryogen Tetrafluoroethane (TFE) for gingival depigmentation procedure. Twelve patients having unaesthetic gingival melanin pigmentation were included in the study. Gingival tissues of eight patients having gingival melanin pigmentation undergoing gingivoplasty or gingivectomy for crownlengthening were exposed to the cryogen and this was used for the histological examination. Gingivectomies were done after 8, 24, 96 hours and after a week of application of tetrafluoroethane. Four fair skinned patients complaining of unaesthetic gingival hyperpigmentation underwent gingival depigmentation using Tetrafluoroethane cryogen. Histologically after 96 hours of application of cryogen there was complete loss of retepegs and epithelial detachment from the corium was evident. Complete re - epithelialisation was noted after a week and was clinically correlated. We therefore, concluded that histologically tetrafluoroethane can effectively destroy gingival epithelium without causing damage to the connective tissue and clinically the color of the gingiva had more pleasing appearance 6 months postoperatively. Hence the cryogen can be used safely for depigmentation procedure.

  7. Hiperplasia epitelial focal (doença de Heck em descendente de índios brasileiros: relato de caso Focal epithelial hyperplasia (Heck's disease in Brazilian indian descent: report of a case

    Directory of Open Access Journals (Sweden)

    Pedro Paulo de Andrade Santos

    2007-12-01

    Full Text Available A hiperplasia epitelial focal, ou doença de Heck, é uma enfermidade rara, benigna, que afeta a mucosa oral de crianças e adultos jovens de diversas regiões do mundo e em diferentes grupos étnicos, como indígenas e esquimós. Apresenta correlação com o papilomavírus humano (HPV no qual os tipos 13 e 32 têm sido consistentemente detectados nessas lesões. Este artigo relata um caso de uma paciente de 18 anos de idade, descendente de índios potiguares, que compareceu ao serviço de estomatologia da Universidade Federal do Rio Grande do Norte (UFRN, exibindo lesões bem definidas, arredondadas, planas, localizadas em cavidade oral, com tempo de evolução de aproximadamente dois anos. As lesões foram submetidas a biópsias incisionais, constatado-se no exame histopatológico alterações epiteliais, como acantose, cristas epiteliais em forma de "taco de golfe" além de células mitosóides. Esses achados histopatológicos foram compatíveis com a hipótese clínica de hiperplasia epitelial focal (doença de Heck.The focal epithelial hyperplasia or Heck's disease is a benign rare pathology, that affects children and young adults oral mucosal in many world regions, and different ethnic groups, for example Indians and Eskimos. Presents correlation with the subtypes 13 and 32 of human papillomavirus (HPV. This article report a case of an 18-year-old patient, descent of potiguar indian, attended in stomatology service of Federal University of Rio Grande do Norte (UFRN, presenting well defined lesions, round, plane, localized in oral cavity with an evolution of two years. The lesions were submitted to incisional biopsies, verifying in histopathologic exam, epithelial alterations, like acanthosis, epithelial projections in "parquet block of golf" beyond mitosoid cells. These histopathological findings were compatible with clinical hypothesis of focal epithelial hyperplasia (Heck's disease.

  8. [Peculiarities of microcirculation indices dynamics in gingival tissues in the process of gingival contour forming by the body of temporary bridge prosthetic].

    Science.gov (United States)

    KIrechina, E K; Riakhovski, A N; Klevno, R V; Parabek, I A; Lapina, S L

    2010-01-01

    Forming was achieved by the action of pressure of intermediate part of immediate denture of ovoid form under visual control up to light ischemia of formed mucous membrane transient in 1-2 minutes, procedure was repeated in 7-10 days during 20-30 days up to the moment of necessary form of gingival contour forming. During gingival contour forming blood flow in gingival tissues reacts by hyperemia development that remains during the whole period of its forming and stops in 1 month after its finish.

  9. Mass spectrometric analysis of gingival crevicular fluid biomarkers can predict periodontal disease progression.

    Science.gov (United States)

    Ngo, L H; Darby, I B; Veith, P D; Locke, A G; Reynolds, E C

    2013-06-01

    Gingival crevicular fluid has been suggested as a possible source of biomarkers for periodontal disease progression. This paper describes a technique for the analysis of gingival crevicular fluid from individual sites using mass spectrometry. It explores the novel use of mass spectrometry to examine the relationship between the relative amounts of proteins and peptides in gingival crevicular fluid and their relationship with clinical indices and periodontal attachment loss in periodontal maintenance patients. The aim of this paper was to assess whether the mass spectrometric analysis of gingival crevicular fluid may allow for the site-specific prediction of periodontal disease progression. Forty-one periodontal maintenance subjects were followed over 12 mo, with clinical measurements taken at baseline and every 3 mo thereafter. Gingival crevicular fluid was collected from subjects at each visit and was analysed using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry. Samples were classified based upon pocket depth, modified gingival index (MGI), plaque index and attachment loss, and were analysed within these groups. A genetic algorithm was used to create a model based on pattern analysis to predict sites undergoing attachment loss. Three hundred and eighty-five gingival crevicular fluid samples were analysed. Twenty-five sites under observation in 14 patients exhibited attachment loss of > 2 mm over the 12-mo period. The clinical indices pocket depth, MGI, plaque levels and bleeding on probing served as poor discriminators of gingival crevicular fluid mass spectra. Models generated from the gingival crevicular fluid mass spectra could predict attachment loss at a site with a high specificity (97% recognition capability and 67% cross-validation). Gingival crevicular fluid mass spectra could be used to predict sites with attachment loss. The use of algorithm-generated models based on gingival crevicular fluid mass spectra may

  10. Immunohistochemical analysis of Langerhans cells in chronic gingivitis using anti-CD1a antibody

    Directory of Open Access Journals (Sweden)

    Shweta Jaitley

    2014-01-01

    Full Text Available Background: The Langerhans cells (LCs are dendritic cells (DCs which belong to the group of antigen presenting cells (APCs. Their function is to recognize the antigen, capture it, and present it to the T lymphocytes; thus initiating an early immune response. The antigen presenting functional LCs may play an important part in initiation and development of gingivitis. The aim of this study was to analyze the density, intraepithelial distribution, and morphology of LCs in gingival epithelium among different age groups with chronic gingivitis and to compare it with that of normal gingiva. Materials and Methods: Immunohistochemistry (IHC was performed to study LCs in normal gingival epithelium (n = 10 and gingival epithelium in chronic gingivitis (n = 30 using anti-CD1a antibody. Mann Whitney U test was performed to compare the density of LCs in normal gingiva with chronic gingivitis. The distribution of LCs in various layers of the epithelium within the three age groups was analyzed using Kruskal-Wallis test. P value less than 0.05 was considered as significant. Results: The density of LCs in chronic gingivitis was significantly higher then that of normal gingiva. Comparing different age groups, the younger individuals had more number of LCs which were located in the superficial layers of gingival epithelium. In chronic gingivitis, higher number of LCs were located in deeper layers when compared with that of normal gingiva. Three morphological types of CD1a positive LCs were observed in normal gingiva, out of which the density of LCs with branched dendritic processes was highest in normal gingiva. Conclusion: The LCs showed variable number, location, and morphology which indicated their adaptation for function in chronic gingivitis.

  11. A novel gingival overgrowth mouse model induced by the combination of CsA and ligature-induced inflammation.

    Science.gov (United States)

    Okanobu, Ai; Matsuda, Shinji; Kajiya, Mikihito; Fujita, Tsuyoshi; Kittaka, Mizuho; Shiba, Hideki; Kurihara, Hidemi

    2017-06-01

    Drug-induced gingival overgrowth (DIGO) is a side effect of the enlargement of gingival tissue by phenytoin, nifedipine, and cyclosporine A (CsA). Gingival inflammation has been identified as a key factor that initiates DIGO. However, a sufficient animal model for clarifying the role of inflammation in DIGO has not yet been generated. We herein describe a novel CsA-induced gingival overgrowth mouse model to evaluate the role of inflammation. A ligature was placed around the second molar in maxillae for 7days to induce gingival inflammation, and CsA (50mg/kg/day) was administered to mice during each experimental period. The severity of gingival overgrowth and mRNA expression of inflammatory cytokines in gingiva were assessed by the gingival overgrowth degree, histological analyses, and RT-PCR. The administration of CsA for 28days in combination with ligation significantly increased the gingival overgrowth degree and expanded the connective tissue area. Increases in the gingival overgrowth degree continued in a time-dependent manner until 21days. Furthermore, the cessation of CsA reduced gingival overgrowth. Thin ligatures (7-0 size) induced weaker tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and IL-6 mRNA expression and less gingival overgrowth than thick ligatures (5-0 ligature). Moreover, the administration of an antibiotic cocktail, which suppressed the expression of these inflammatory cytokines in gingiva, attenuated gingival overgrowth induced by ligatures and CsA. These results suggest that inflammation in gingival tissue plays a role in initiating CsA-induced gingival overgrowth. This gingival overgrowth mouse model has potential for elucidating the etiology of DIGO from the view point of gingival inflammation. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. Keadaan Oral Hygiene Dan Gingivitis Serta Faktor-Faktor Yang Mempengaruhinya Pada Anak SD Muhammadiyah 28 Kecamatan Medan Timur

    OpenAIRE

    Muhammad Syafri

    2008-01-01

    Gingivitis merupakan penyakit periodontal stadium awal berupa peradangan pada gingiva, termasuk penyakit paling umum yang sering ditemukan pada jaringan mulut. Gingivitis yang ringan umumnya tidak segera mendapatkan perhatian karena tidak menimbulkan rasa sakit atau gangguan fungsi, akan tetapi jika keadaan ini dibiarkan, gingivitis dapat menjadi bentuk yang destruktif. Prevalensi gingivitis dapat berkurang dengan bertambah baiknya status oral hygiene, pasok flour yang memadai, diet yang baik...

  13. Effect of Light Conducting Cylindrical Inserts on Gingival Microleakage

    Directory of Open Access Journals (Sweden)

    SM. Moazzami

    2007-03-01

    Full Text Available Objective: Microleakage in the gingival floor of class II composite restorations can compromise the marginal adaptation of the filling material to the cavity edges. The aim of this study was to evaluate the effect of light conducting cylindrical inserts in decreasing the microleakage of the gingival floor in cavities 1mm below the CEJ.Materials and Methods: Eighty maxillary first molars were randomly divided into eight groups according to use of glass inserts, type of resin (Coltene unfilled resin versus Scotchbond multi purpose and filling technique (one-unit versus incremental. Proximal class II cavities were prepared in all samples with the gingival floor one millimeter below the CEJ. Etched and silan-treated glass inserts were made from 2mm cylindrical bioglass material and cavities were restored according to research protocol. The samples were subjected to 2500 thermal cycles (5-55oC, immersed in 0.5% basic fuchsin solution, embedded in epoxy resin and cut centrally and laterally (buccally or lingually in a mesiodistal direction. Microleakage was scored and collected data were statistically analyzed using Kruskal-Wallis and Mann-Whitney tests.Results: Minimal dye penetration was observed in the group that employed the incre-mental technique along with Scotchbond, with or without glass inserts. A significant difference was observed between the eight groups. In addition the use of the incremental technique and glass inserts had a significant effect on the microleakage of lateral and central sections, respectively. Application of dentin bonding agent signifi-cantly affected both sections.Conclusion: Glass inserts were effective in decreasing cervical microleakage of class II cavities restored with composite resin.

  14. Gingival microleakage of class V composite restorations with fiber inserts.

    Science.gov (United States)

    Ahmed, Walaa; El-Badrawy, Wafa; Kulkarni, Gajanan; Prakki, Anuradha; El-Mowafy, Omar

    2013-07-01

    This study investigated the effect of different fiber inserts (glass and polyethylene), bonding agents, and resin composites on the gingival margin microleakage of class V composite restorations. Sixty premolars were sterilized and mounted in acrylic resin bases. Class V cavities were prepared buccally and lingually, 1 mm below the cementoenamel junction, comprising 12 groups (n = 10). In the experimental groups fiber inserts were cut and placed at the gingival seat, while the control groups had no inserts. Combinations of two composite materials, Filtek-Z250 and Filtek-LS (3M-ESPE), and four bonding agents, Clearfil SE bond (Kuraray) (C), Scotch Bond Multipurpose (3M-ESPE) (SB), Prime and Bond NT (Dentsply) (PB), and Filtek-LS (3M-ESPE) (LS) were used. Restorations were incrementally inserted and polymerized for 40s. Specimens were then stored in distilled water for 7 days and thermocycled for 500 cycles. Teeth surfaces were sealed with nail polish except for 1 mm around restoration margins and immersed in 2% red procion dye. Teeth were then sectioned buccolingually and dye penetration was assessed with five-point scale. Data were statistically-analyzed by Kruskal-Wallis, ANOVA and Tukey's tests (α = 5%). Mean microleakage scores varied from 0.40 (Groups C, C with polyethylene, LS, LS with polyethylene) to 1.50 (SB). Different bonding agents led to differences in microleakage scores where C and LS showed significantly lower microleakage than PB. SB had highest mean microleakage score, however, incorporation of fibers resulted in significant reduction in microleakage. Class V resin composite restorations bonded with a total-etch adhesive had a significant reduction in mean microleakage scores when glass or polyethylene fibers were placed at the gingival cavo-surface margin. In contrast, for two self-etch adhesive systems, the incorporation of fibers had no significant effect on mean microleakage scores.

  15. Root resorption leading to linkage of dentinal collagen and gingival fibers? A case report.

    Science.gov (United States)

    Stahl, S S; Tarnow, D

    1985-05-01

    A maxillary central incisor in a 55-year-old Caucasian female was extracted in modified block as part of a histologic study of gingival responses to subgingival crown placement. The facial portion of this block showed preclinical pocket depth of 1.0 mm with moderate gingival inflammation. The block was extracted 2 weeks after crown placement and prepared for histologic evaluation. Histologic responses to subgingival crown placement were, among others: gingival recession (1.0 mm), reformation of crevicular depth (0.7 mm) and remodelling of the gingival and periodontal attachment apparatus. Histologic evaluations of the gingival unit using cellular and connective tissue stains revealed an area of root resorption immediately apical to the junctional epithelium at a portion of the facial surface. Root resorption had progressed into dentin. Gingival connective tissue abutted the dentinal surface. Collagen stains showed the presence of tufts of collagen fibrils which appeared to arise from the dentin. These fibrillar elements seemed to splice with collagen fibrils found in the gingival connective tissue. The specimen thus suggests the possibility of a fiber linkage attachment involving exposed dentinal fibers as part of gingival repair following injury.

  16. Effectiveness of feeding large kibbles with mechanical cleaning properties in cats with gingivitis

    NARCIS (Netherlands)

    Vrieling, HE; Theyse, LFH; van Winkelhoff, AJ; Dijkshoorn, NA; Logan, EI; Picovet, P

    2005-01-01

    Effectiveness of feeding large kibbles with mechanical cleaning properties in cats with gingivitis periodontal disease is the most common acquired oral disease in cats. it starts with plaque accumulation and gingivitis. The aim of this study was to evaluate the effectiveness of different types of

  17. Prevalence and severity of plaque-induced gingivitis in a Saudi adult population.

    Science.gov (United States)

    Idrees, Majdy M; Azzeghaiby, Saleh N; Hammad, Mohammad M; Kujan, Omar B

    2014-11-01

    To evaluate the prevalence and severity of plaque-induced gingivitis among a Saudi adult population in Riyadh region. Three hundred and eighty-five eligible participants in this cross-sectional study were recruited from routine dental patients attending the oral diagnosis clinic at Al-Farabi College in Riyadh, Saudi Arabia from June 2013 to December 2013. A clinical examination was performed by 2 dentists to measure the gingival and plaque indices of Löe and Silness for each participant. The prevalence of gingivitis was 100% among adult subjects aged between 18-40 years old. Moreover, the mean gingival index was 1.68±0.31, which indicates a moderate gingival inflammation. In fact, males showed more severe signs of gingival inflammation compared with females (p=0.001). In addition, the mean plaque index was 0.875±0.49, which indicates a good plaque status of the participants. Interestingly, the age was not related either to the gingival inflammation (p=0.13), or to the amount of plaque accumulation (p=0.17). However, males were more affected than females (p=0.005). The results of this study show that plaque accumulation is strongly associated with high prevalence of moderate to severe gingivitis among Saudi subjects. 

  18. Gingival labial recessions in orthodontically treated and untreated individuals : a case control study

    NARCIS (Netherlands)

    Renkema, Anne Marie; Fudalej, Piotr S.; Renkema, Alianne A. P.; Abbas, Frank; Bronkhorst, Ewald; Katsaros, Christos

    Objectives To evaluate the long-term development of labial gingival recessions during orthodontic treatment and retention phase. Material and Methods In this retrospective casecontrol study, the presence of gingival recession was scored (Yes or No) on plaster models of 100 orthodontic patients

  19. Effect of Oral Curcuma Gel in Gingivitis Management - A Pilot Study

    OpenAIRE

    Farjana, H Nilofer; Chandrasekaran, S. C.; Gita, Bagavad

    2014-01-01

    Background: Various modalities of treatments are available for gingival disease, but there are adverse effects of these conventional compounds. This led to the search of natural products which are highly beneficial and biocompatible. Turmeric is one such novel product obtained from plants, known for its varied medicinal value. In dentistry, it plays a role treating gingival and periodontal disease.

  20. Cytomorphometric analysis of the gingival epithelium in type 2 diabetic patients with and without smoking habit

    Directory of Open Access Journals (Sweden)

    Punit Vaibhav Patel

    2013-01-01

    Conclusions: There were significant alterations in the cellular pattern of gingival mucosa cells in a non-smoker diabetic, but the alteration was to a greater extent in smoker diabetics demonstrating a synergistic effect of smoking and diabetes on gingival mucosa.

  1. Gingival abrasion and recession in manual and oscillating-rotating power brush users

    NARCIS (Netherlands)

    Rosema, N.A.M.; Adam, R.; Grender, J.M.; van der Sluijs, E.; Supranoto, S.C.; van der Weijden, G.A.

    2014-01-01

    Objective To assess gingival recession (GR) in manual and power toothbrush users and evaluate the relationship between GR and gingival abrasion scores (GA). Methods This was an observational (cross-sectional), single-centre, examiner-blind study involving a single-brushing exercise, with 181 young

  2. Assessment of relationship between oral health behavior, oral hygiene and gingival status of dental students

    Directory of Open Access Journals (Sweden)

    Afsheen Lalani

    2015-01-01

    Conclusion: Thus, it is concluded that there is a significant relationship between the oral health behavior, oral hygiene, and gingival status of dental students. Dental students with better self-reported oral health behavior had lower plaque and gingival scores indicating a better attitude toward oral health.

  3. The assessment of the gingival capillary density with orthogonal spectral polarization (OPS) imaging

    NARCIS (Netherlands)

    Lindeboom, J. A.; Mathura, K. R.; Ramsoekh, D.; Harkisoen, S.; Aartman, I. H.; van den Akker, H. P.; Ince, C.

    2006-01-01

    OBJECTIVE: In this study we evaluated the inter-observer agreement in the assessment of gingival capillary density using Orthogonal Polarization Spectral Imaging. METHODS: In this study gingival capillary density of 100 healthy subjects was determined by 2 independent observers. Agreement was

  4. Effect of health education on oral hygiene and gingival status of ...

    African Journals Online (AJOL)

    The prevalence of plaque among the participants in the intervention decreased from 70.6% to 18.6%, with a significant decrease in their mean plaque score, from 0.89 to 0.15. The prevalence of gingival inflammation in the intervention group decreased from 58.2% to 12.7%, with a significant decrease in the mean gingival ...

  5. Cetylpyridinium chloride mouth rinses alleviate experimental gingivitis by inhibiting dental plaque maturation

    Science.gov (United States)

    Teng, Fei; He, Tao; Huang, Shi; Bo, Cun-Pei; Li, Zhen; Chang, Jin-Lan; Liu, Ji-Quan; Charbonneau, Duane; Xu, Jian; Li, Rui; Ling, Jun-Qi

    2016-01-01

    Oral rinses containing chemotherapeutic agents, such as cetylpyridinium chloride (CPC), can alleviate plaque-induced gingival infections, but how oral microbiota respond to these treatments in human population remains poorly understood. Via a double-blinded, randomised controlled trial of 91 subjects, the impact of CPC-containing oral rinses on supragingival plaque was investigated in experimental gingivitis, where the subjects, after a 21-day period of dental prophylaxis to achieve healthy gingivae, received either CPC rinses or water for 21 days. Within-subject temporal dynamics of plaque microbiota and symptoms of gingivitis were profiled via 16S ribosomal DNA gene pyrosequencing and assessment with the Mazza gingival index. Cetylpyridinium chloride conferred gingival benefits, as progression of gingival inflammation resulting from a lack of dental hygiene was significantly slower in the mouth rinse group than in the water group due to inhibition of 17 gingivitis-enriched bacterial genera. Tracking of plaque α and β diversity revealed that CPC treatment prevents acquisition of new taxa that would otherwise accumulate but maintains the original biodiversity of healthy plaques. Furthermore, CPC rinses reduced the size, local connectivity and microbiota-wide connectivity of the bacterial correlation network, particularly for nodes representing gingivitis-enriched taxa. The findings of this study provide mechanistic insights into the impact of oral rinses on the progression and maturation of dental plaque in the natural human population. PMID:27680288

  6. The gingival condition of oral contraceptives users at desa Hegarmanah, Kecamatan Jatinangor

    Directory of Open Access Journals (Sweden)

    Miduk Sibuea

    2010-03-01

    Full Text Available The change of hormonal condition is a systemic condition that affected the periodontium condition. Oral contraceptives is one of the systemic risk that can change hormonal condition. The purpose of the research was to evaluate gingival condition of oral contraceptives users and to find the difference of gingival condition between users and non users of oral contraceptives at Desa Hegarmanah, Kecamatan Jatinangor. The research method was descriptive analytic with purposive sampling, consist of 69 users and 30 non users of oral contraceptives. The gingival condition was scored by using Loe and Sillnes gingival index. The research showed that the average of gingival index in oral contraceptives users was 1.913 and non users was 1.707. The statistic analysis was U Mann Whitney non parametric test and the α was 5% showed that there was a significant difference of gingival condition between users and non users of oral contraceptives. The conclusion of the research was the gingival condition of oral contraceptives users was different with non users at Desa Hegarmanah Kecamatan Jatinangor but clinically was the same, that is in moderate gingivitis category.

  7. Salivary Cytoprotective Proteins in Inflammation and Resolution during Experimental Gingivitis--A Pilot Study.

    Science.gov (United States)

    Aboodi, Guy M; Sima, Corneliu; Moffa, Eduardo B; Crosara, Karla T B; Xiao, Yizhi; Siqueira, Walter L; Glogauer, Michael

    2015-01-01

    The protective mechanisms that maintain periodontal homeostasis in gingivitis and prevent periodontal tissue destruction are poorly understood. The aim of this study was to identify changes in the salivary proteome during experimental gingivitis. We used oral neutrophil quantification and whole saliva (WS) proteomics to assess changes that occur in the inflammatory and resolution phases of gingivitis in healthy individuals. Oral neutrophils and WS samples were collected and clinical parameters measured on days 0, 7, 14, 21, 28, and 35. Increased oral neutrophil recruitment and salivary cytoprotective proteins increased progressively during inflammation and decreased in resolution. Oral neutrophil numbers in gingival inflammation and resolution correlated moderately with salivary β-globin, thioredoxin, and albumin and strongly with collagen alpha-1 and G-protein coupled receptor 98. Our results indicate that changes in salivary cytoprotective proteins in gingivitis are associated with a similar trend in oral neutrophil recruitment and clinical parameters. We found moderate to strong correlations between oral neutrophil numbers and levels of several salivary cytoprotective proteins both in the development of the inflammation and in the resolution of gingivitis. Our proteomics approach identified and relatively quantified specific cytoprotective proteins in this pilot study of experimental gingivitis; however, future and more comprehensive studies are needed to clearly identify and validate those protein biomarkers when gingivitis is active.

  8. Hereditary hyperplastic gingivitis in North American farmed silver fox (Vulpes vulpes)

    Science.gov (United States)

    Clark, Jo-Anna B.J.; Hudson, Robert C.; Marshall, H. Dawn

    2015-01-01

    Hereditary hyperplastic gingivitis is a progressive growth of gingival tissues in foxes resulting in dental encapsulation. It is an autosomal recessive condition displaying a gender-biased penetrance, with an association with superior fur quality. This disease has been primarily described in European farmed foxes. Here we document its emergence in Canada. PMID:25829563

  9. Expression of antimicrobial peptides and interleukin-8 during early stages of inflammation: An experimental gingivitis study.

    Science.gov (United States)

    Dommisch, H; Staufenbiel, I; Schulze, K; Stiesch, M; Winkel, A; Fimmers, R; Dommisch, J; Jepsen, S; Miosge, N; Adam, K; Eberhard, J

    2015-12-01

    In the oral cavity, the epithelial surface is constantly exposed to a number of different microorganisms that are organized in a well-structured biofilm. The aim of this study was to monitor gingival expression of antimicrobial peptides (AMPs) and interleukin-8 (IL-8) in an early gingivitis model. Experimental gingivitis was allowed to develop in healthy volunteers (n = 17). Bleeding on probing (BOP%) and gingival crevicular fluid volume (GCF) were assessed at baseline and day 1, 3, 5, 7 and 14. Expression of AMPs (human beta-defensin-2, hBD-2; CC-chemokine ligand 20, CCL20; psoriasin, pso/S100A7) and IL-8 was analyzed by immunohistochemistry in gingival biopsies. In addition, hBD-2 and IL-8 protein expression was monitored in GCF using the ELISA technology. Experimental gingivitis gradually developed with an increase in BOP scores and GCF volume over time. In GCF, elevated concentrations of hBD-2 and IL-8 were monitored at day 1, 5 and 7 (p ≤ 0.0002). Immunohistochemical analysis of gingival sections demonstrated increased staining for hBD-2 at day 3, whereas the CCL20, pso/S100A7, and IL-8 expression was increased at later time points (p gingival inflammation. Differential temporal expression for AMPs may ensure a constant antimicrobial activity against changes in the bacterial composition of the growing dental biofilm. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  10. PENGARUH SKELING DENGAN DAN TANPA OBAT KUMUR DARI JUS LIDAH BUAYA (Aloe vera) TERHADAP PENDERITA GINGIVITIS

    OpenAIRE

    Fahruddin, Andi Muhammad

    2015-01-01

    2015 Latar belakang : Berdasarkan hasil Survei Kesehatan Rumah Tangga (SKRT) tahun 2010 Departemen Kesehatan RI menunjukkan bahwa 63% penduduk Indonesia menderita penyakit gigi dan mulut, meliputi karies gigi dan penyakit jaringan periodontal. Salah satu penyakit periodontal yang sering terjadi adalah gingivitis. Gingivitis merupakan bentuk respon protektif gingiva yang ditandai dengan warna kemerahan, pembesaran jaringan, tendensi terjadi perdarahan saat probing dan peni...

  11. Candida spp. and gingivitis in children with nephrotic syndrome or type 1 diabetes.

    Science.gov (United States)

    Olczak-Kowalczyk, Dorota; Pyrżak, Beata; Dąbkowska, Maria; Pańczyk-Tomaszewska, Małgorzata; Miszkurka, Grażyna; Rogozińska, Izabela; Swoboda-Kopeć, Ewa; Gozdowski, Dariusz; Kalińska, Angelika; Piróg, Anna; Mizerska-Wasiak, Małgorzata; Roszkowska-Blaim, Maria

    2015-05-08

    Diabetes and Nephrotic syndrome (NS) promote plaque-related gingivitis and yeast-like fungal infections. The study assesses the impact of Candida spp. and general disease- or treatment-related factors on plaque-related gingivitis severity in children and adolescents with Nephrotic syndrome /diabetes. Body mass index (BMI), BMI standard deviation score, and oral cavity (Plaque Index--PLI, Gingival Index--GI, mucosa status, presence and Candida enzymatic activity) were assessed in 96 patients (32 with NS: 30- immunosuppressive treatment, 35--type 1 diabetes, and 29 generally healthy), aged; 3-18 years. Laboratory included cholesterol and triglyceride measurements; in diabetic subjects- glycated haemoglobin, in NS: total protein, albumin, creatinine, haemoglobin, haematocrit, white cell count, urinary protein excretion. Medical records supplied information on disease duration and treatment. A statistical analysis was performed; Kendall Tau coefficient, chi-square test, t-test, and multiple regression analysis ( P Gingivitis occurred more frequently in patients with NS/diabetes. Gingivitis severity was correlated with PLI, age, and yeast enzyme activity in NS--to with immunosuppressive treatment with >1 drug, drug doses, treatment duration, lipid disorders, and BMI; in diabetes, with blood glucose and glycated haemoglobin >8%. Poor hygiene control is the main cause of gingivitis. Gingivitis severity is most likely related to age, lipid disorders and increase in body mass. Candida spp., in uncompensated diabetes and in those using immunosuppressive treatment, might intensify plaque-related gingivitis.

  12. Comparison between aluminum chloride and tetryzoline hydrochloride for control of vertical gingival displacement and crevicular fluid

    Directory of Open Access Journals (Sweden)

    Clóvis Lamartine de MORAES MELO NETO

    2017-08-01

    Full Text Available Abstract Introduction The use of a gingival displacement cord with a gingival displacement substance is a common procedure for taking a quality impression of the cervical terminal in teeth for prosthetic purposes. Objective To evaluate whether the mechanical-chemical method with 0.05% tetryzoline hydrochloride or 25% aluminum chloride is capable of reducing crevicular fluid, and displacing a statistically significant larger quantity of gingival tissue vertically, compared with the mechanical method (without chemical substances. Material and method Ten patients were selected, and then No. 000 and 1 Ultrapak cords were randomly positioned on teeth 13, 21 and 23. Group I – cord with no chemical substance; Group II – cords impregnated with tetryzoline hydrochloride and Group III – cords impregnated with aluminum chloride. Using dental stone models, thirty images were captured with a camera coupled to a loupe to analyze the degree of gingival displacement. Crevicular fluid was quantified using a high-precision scale and individualized strips of absorbent paper for each tooth on which gingival displacement was performed. Result There was no statistical difference between the three groups relative to the amount of vertical gingival displacement (Anova, p=0.26. As regards reduction in crevicular fluid, there was no difference between the test and control groups (Wilcoxon and Friedman, p < 0.05. Conclusion The use of tetryzoline hydrochloride or aluminum chloride to impregnate the gingival displacement cord did not improve the quantity of vertical gingival displacement and did not reduce the amount of crevicular fluid.

  13. Assessment of periostin levels in serum and gingival crevicular fluid of patients with periodontal disease.

    Science.gov (United States)

    Balli, U; Keles, Z P; Avci, B; Guler, S; Cetinkaya, B O; Keles, G C

    2015-12-01

    Periostin, a secreted adhesion molecule essential for periodontal tissue integrity, is highly expressed in the periodontal ligament and plays a critical role in tooth and bone development. The purpose of this study was to investigate periostin levels in the gingival crevicular fluid and serum of patients with periodontal disease and compare them with those of healthy individuals. Eighty individuals (41 males and 39 females; age range: 25-48 years) were enrolled in the study. Individuals were divided into three groups following clinical and radiographic examinations: the periodontal-healthy group (n = 20), gingivitis group (n = 30) and chronic periodontitis group (n = 30). Gingival crevicular fluid and serum samples were collected and periostin levels were determined using the enzyme-linked immunosorbent assay. The total amount and concentration of periostin decreased in gingival crevicular fluid with the progression and severity of the disease from healthy controls to gingivitis and to chronic periodontitis groups and differed significantly (p 0.05). Periostin in gingival crevicular fluid negatively correlated with the gingival index in the periodontal disease groups, whereas it is inversely correlated with the clinical attachment level only in the periodontitis group (p periodontal disease, and negatively correlated with the clinical parameters. Within the limits of the study, the periostin level in gingival crevicular fluid can be considered a reliable marker in the evaluation of periodontal disease susceptibility and activity. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  14. Surgical treatment of gingival recessions using Emdogain gel : Clinical procedure and case reports

    NARCIS (Netherlands)

    Abbas, F; Wennstrom, J; Van der Weijden, F; Schneiders, T; Van der Velden, U

    2003-01-01

    This article describes the clinical procedure and outcome of surgical treatment of gingival recessions with the adjunctive use of Emdogain gel, an enamel matrix derivative bioactive material for periodontal reconstructive surgery. Six cases with gingival recession on maxillary canines are presented

  15. Measurement of gingival thickness using digital vernier caliper and ultrasonographic method: a comparative study.

    Science.gov (United States)

    Sharma, Swati; Thakur, Srinath L; Joshi, Shyamsunder K; Kulkarni, Sudhindra S

    2014-05-01

    The measurement of the thickness of the gingival tissues has been done using different techniques. Trans-gingival probing with a graduated probe, use of vernier calipers, ultrasonography and cone-beam computed tomography (CBCT), have all been tried, but no one technique has been shown to be consistent and better than the others. The present study was done to evaluate and compare the gingival thickness as measured with a digital vernier caliper and ultrasonography. A total of 30 systemically healthy, non-smokers were included in the study. The gingival measurements were made and recorded from the maxillary and mandibular lateral incisor areas at 2 locations: (a) at a point apical to the free gingival groove; and (b) at a point immediately coronal to the muco-gingival junction. The mean gingival thickness ranged from 0.56 to 1.02 mm. Males had a significantly thicker gingiva as compared to females (P vernier caliper and those made with ultrasonography were compared. The thickness of the gingiva was in the range of 0.56-1.02 mm. A digital vernier caliper and ultrasonography both can be used to assess the gingival thickness with equal accuracy. © 2013 Wiley Publishing Asia Pty Ltd.

  16. Gene Polymorphism in Amlodipine Induced Gingival Hyperplasia: A Case Report

    OpenAIRE

    Charles, NSC; Ramesh, V; Babu, Kennedy SPK; Premalatha, B

    2012-01-01

    The management of cardiovascular disorders poses a dilemma for the medical fraternity. Calcium channel blockers are one of the most commonly used drugs for the management of this disorder, and it is also a well known fact that they are one of the most common group of drugs responsible for causing gingival over growth as one of their adverse effects. Amlodipine is a new generation hypertensive, which has found wide acceptance and usage due to its duration of action. Even with all its benefits ...

  17. Onychophagia and postorthodontic isolated gingival recession: diagnosis and treatment.

    Science.gov (United States)

    Alessandri Bonetti, Giulio; Incerti Parenti, Serena; Zucchelli, Giovanni

    2012-12-01

    This clinical report describes the diagnosis and the management of isolated-type recession defects of complex etiology in 2 healthy postorthodontic patients. The lesions were confined to 1 mandibular incisor and were associated with an abnormal buccolingual inclination of the affected tooth despite a lingual retainer made with a round stainless steel twisted wire. After careful questioning, it was determined that the recession defects were indirect effects of habitual onychophagia. The concomitant fingernail-biting habit and the lingual bonded retainer led to the indirect development of bone dehiscence and, consequently, gingival recession. Copyright © 2012 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  18. [Bilaminar technic in the treatment of gingival recessions].

    Science.gov (United States)

    Blasi, G; Viti, M

    1989-02-01

    Bilaminar procedures represent an evolution in the treatment of marginal tissue recessions. A connective tissue graft removed from the palate and over which a pedicle flap is sutured, is used in these procedures. The advantages of these new procedures are: 1) sure predictability of graft survival to which a double-blood supply is guaranteed; 2) primary intention healing at the donor site, with minimum post-operative discomfort; 3) excellent esthetic results consisting of better color blending between graft and adjacent tissues and absence of keloid- like scars, very common after free gingival grafts.

  19. Efecto antiinflamatorio de apitoxina de Apis mellifera sobre prostaglandina E2 del fluido crevicular gingival de pacientes con y sin enfermedad periodontal, sometidos a apiterapia: ensayo preliminar

    OpenAIRE

    Faúndez Poblete,W; Narváez Carrasco, C.G.; Burgos Arias, A.

    2011-01-01

    Introducción: La apitoxina que es producida por la Apis mellifera posee efecto antiinflamatorio sobre una serie de marcadores biológicos. La prostaglandina E2 forma parte de ellos, estando presente en el fluido gingival crevicular (FGC). La prostaglandina E2 es evidenciada en la enfermedad periodontal. Objetivo: En este estudio se evaluó el efecto antiinflamatorio de la apitoxina sobre la concentración de prostaglandina E2 del FGC de un paciente sin enfermedad periodontal (SEP) y otro con enf...

  20. Detección de herpesvirus y bacterias periodontopatógenas en muestras de fluido crevicular gingival y saliva en periodontitis crónica

    OpenAIRE

    Herrero Sánchez, Alicia

    2016-01-01

    En los últimos 15 años, se ha sugerido que ciertos herpesvirus, en particular, el citomegalovirus (CMV) y el virus de Epstein-Barr (VEB), podrían tener cierto papel en el inicio y progresión de las enfermedades periodontales. Sin embargo, en la mayoría de los trabajos, no se han podido obtener resultados concluyentes. Por otro lado, aunque el método de referencia actual para el estudio microbiológico de los patógenos periodontales es la toma de muestras en fluido crevicular gingival (FCG), se...

  1. Gingival recession: its causes and types, and the importance of orthodontic treatment

    Directory of Open Access Journals (Sweden)

    Ana Suzy Jati

    Full Text Available abstract Gingival recession has direct causes and predisposing factors. Orthodontic treatment is able to prevent recession and even contribute to its treatment, with or without periodontal approach, depending on the type and severity of gingival tissue damage. There is no evidence on the fact that orthodontic treatment alone might induce gingival recession, although it might lead the affected teeth (usually mandibular incisors or maxillary canines to be involved in situations that act as predisposing factors, allowing direct causes to act and, therefore, trigger recession, especially when the buccal bone plate is very thin or presents with dehiscence. Several aspects regarding the relationship between orthodontic treatment and gingival recession have been addressed, and so has the importance of the periosteum to the mechanism of gingival recession formation. Clinical as well as experimental trials on the subject would help to clarify this matter, of which understanding is not very deep in the related literature.

  2. Gingival recession: its causes and types, and the importance of orthodontic treatment.

    Science.gov (United States)

    Jati, Ana Suzy; Furquim, Laurindo Zanco; Consolaro, Alberto

    2016-06-01

    Gingival recession has direct causes and predisposing factors. Orthodontic treatment is able to prevent recession and even contribute to its treatment, with or without periodontal approach, depending on the type and severity of gingival tissue damage. There is no evidence on the fact that orthodontic treatment alone might induce gingival recession, although it might lead the affected teeth (usually mandibular incisors or maxillary canines) to be involved in situations that act as predisposing factors, allowing direct causes to act and, therefore, trigger recession, especially when the buccal bone plate is very thin or presents with dehiscence. Several aspects regarding the relationship between orthodontic treatment and gingival recession have been addressed, and so has the importance of the periosteum to the mechanism of gingival recession formation. Clinical as well as experimental trials on the subject would help to clarify this matter, of which understanding is not very deep in the related literature.

  3. Effect of oral curcuma gel in gingivitis management - a pilot study.

    Science.gov (United States)

    Farjana, H Nilofer; Chandrasekaran, S C; Gita, Bagavad

    2014-12-01

    Various modalities of treatments are available for gingival disease, but there are adverse effects of these conventional compounds. This led to the search of natural products which are highly beneficial and biocompatible. Turmeric is one such novel product obtained from plants, known for its varied medicinal value. In dentistry, it plays a role treating gingival and periodontal disease. To evaluate the clinical efficacy of oral curcuma gel in gingivitis and to assess any adverse effects of the gel. This pilot study comprises of 10 individuals with severe gingivitis. They were made to apply oral curcuma gel for a period of 21 days. The papillary bleeding index (PBI) were assessed before and after along with visual analogue scale. The obtained data was statistically analysed. The data was analysed with Pearson Spearman's correlation coefficient and paired 't' test. The results were statistically significant with p<0.001. The gel containing curcuma longa extract was efficient in treating gingivitis by reducing its inflammatory components.

  4. Journey From Black To Pink Gums: Management Of Melanin Induced Physiological Gingival Hyper Pigmentation.

    Science.gov (United States)

    Farid, Huma; Shinwari, Muhammad Saad; Khan, Farhan Raza; Tanwir, Farzin

    2017-01-01

    Smile is an expression of happiness, self-confidence, kindness and beauty. Along with teeth and lips, gingiva is also a vital component of smile. Melanin induced gingival hyper pigmentation may appear un-aesthetic especially when it is associated with high smile line, upper anterior labial segment and is uneven in appearance. It affects individuals from all races. Generally, it is believed that melanin induced gingival hyper pigmentation is confined to individuals from dark races. But studies have shown that Iranian, Indian, Italian, Arabian, Greek. German, French, Japanese, Chinese, Jewish, Thai, Malaysian and other ethnic groups also display clinical gingival pigmentation.1 Gingival hyper pigmentation may result in psychological distress especially when the appearance is of utmost importance for the individuals. This article aims to focus on the physiology, clinical appearance and treatment options available for the melanin induced gingival hyper pigmentation along with the reported recurrence in the light of current literature.

  5. Connective Tissue Graft for Gingival Recession in Mandibular Incisor Area: A Case Report.

    Science.gov (United States)

    Egawa, Masahiro; Inagaki, Satoru; Tomita, Sachiyo; Saito, Atsushi

    2016-01-01

    We report a case of gingival recession in the mandibular incisor region requiring a connective tissue graft. The patient was a 17-year-old girl who visited the Tokyo Dental College Chiba Hospital in 2014 with the chief complaint of gingival recession in the lower incisor region. She had received orthodontic treatment for 5 years and noticed the gingival recession on completion of active orthodontic treatment in 2013. Gingival recession in tooth #31 extended 3 mm beyond the muco-gingival junction (MGJ) and was clinically diagnosed as Miller Class II recession; probing depth was 6 mm. Following initial periodontal therapy, a connective tissue graft procedure was implemented. The connective tissue was harvested from the left palate. Healing was uneventful, and the grafted site showed a favorable outcome at 6 months postoperatively. We are continuing to carefully monitor the condition of periodontal tissue.

  6. Scalpel Depigmentation and Surgical Crown Lengthening to Improve Anterior Gingival Esthetics.

    Science.gov (United States)

    Chethana, K C; Pradeep, K

    2016-01-01

    A smile is a mesmerizing expression of joy, success, courtesy and reveals self-confidence. The harmony of the smile is determined not only by the shape, position and the color of teeth, but also by the gingival architecture. Gingival tissues form an important part of what we can consider to be a pleasing smile. The elegance of this pleasant smile could be, affected by highly pigmented gingiva. This gingival pigmentation occurs as a result of melanin granules, which are produced by melanoblast. Although melanin pigmentation does not present a medical problem, demand for cosmetic therapy is commonly sort by people with moderately pigmented gingiva. This case report highlights, a case of excessive gingival display and hyperpigmentation treated with anterior crown lengthening and gingival depigmentation using the scalpel technique.

  7. Anterior esthetic gingival depigmentation and crown lengthening: report of a case.

    Science.gov (United States)

    Roshna, T; Nandakumar, K

    2005-08-15

    Excessive gingival display space and gingival hyperpigmentation are major concerns for a large number of patients visiting the dentist. Melanin hyperpigmentation usually does not present a medical problem, but patients usually complain of dark gums as unaesthetic. This problem is aggravated in patients with a "gummy smile" or excessive gingival display while smiling. Esthetic periodontal plastic surgery is especially rewarding in such individuals with compromised esthetics. A case is reported here on the cosmetic correction of "black gums" and "gummy smile." Periodontal plastic surgery combining gingival depigmentation and esthetic crown lengthening was performed in a single appointment using scalpel surgical technique. The outline of steps involved in the surgical procedure is demonstrated and a brief review of the various gingival depigmentation techniques is depicted here.

  8. The efficacy of a herbal-based toothpaste on the control of plaque and gingivitis.

    Science.gov (United States)

    Mullally, B H; James, J A; Coulter, W A; Linden, G J

    1995-09-01

    A double-blind controlled clinical trial with parallel groups was designed to investigate the effectiveness of a herbal-based toothpaste in the control of plaque and gingivitis as compared with a conventional dentifrice. 70 subjects with gingivitis completed the 6-week study. All participants had at least 20 natural teeth with no probing depths greater than 3 mm and a plaque index of 2 or more at baseline. At baseline, both groups were balanced for the parameters measured: plaque index, plaque vitality, gingival index, bleeding on probing and gingival crevicular fluid flow. At the end of the trial, there were reductions within both groups, however, there were no significant differences between the groups. It was concluded that the herbal based toothpaste was as effective as the conventionally formulated dentifrice in the control of plaque and gingivitis.

  9. Hubungan Kebersihan Gigi dan Mulut dengan Gingivitis pada Siswa Sekolah Dasar Kelas V Di Kabupaten Jember

    Directory of Open Access Journals (Sweden)

    Hestieyonini Hadnyanawati

    2015-09-01

    Full Text Available Oral hygiene determines by food debris, plaque, calculus, material alba, and stain at surface of tooth. The main cause of gingivitis is plaque, with following anomaly periodontal. The purpose of this study is to know the correlation of oral hygiene and gingivitis of class V (five elementary school students in Kabupaten Jember. Method cross sectional was use in this study, and sample was taken by Stratified Random Sampling. Material and tools uses in this study are mouth glass, sonde, pincer, probe periodontal, sterile cotton, and alcohol 70%. The respondents examined and write OHI-S status and GI status. The result indicated that OHI-S status was relation with becomes gingivitis. Students with bad OHI-S status will become gingivitis (100%. This data was test by Chi square (X2, and indicated that there is correlation between oral hygiene and gingivitis (p = 0,000.

  10. The effectiveness of dentifrices without and with sodium lauryl sulfate on plaque, gingivitis and gingival abrasion--a randomized clinical trial.

    Science.gov (United States)

    Sälzer, S; Rosema, N A M; Martin, E C J; Slot, D E; Timmer, C J; Dörfer, C E; van der Weijden, G A

    2016-04-01

    The aim of this study was to compare the efficacy of a dentifrice without sodium lauryl sulfate (SLS) to a dentifrice with SLS in young adults aged 18-34 years on gingivitis. One hundred twenty participants (non-dental students) with a moderate gingival inflammation (bleeding on probing at 40-70 % of test sites) were included in this randomized controlled double blind clinical trial. According to randomization, participants had to brush their teeth either with dentifrice without SLS or with SLS for 8 weeks. The primary outcome was bleeding on marginal probing (BOMP). The secondary outcomes were plaque scores and gingival abrasion scores (GA) as well as a visual analogue scale (VAS) score at exit survey. Baseline and end differences were analysed by univariate analysis of covariance (ANCOVA) test, between group differences by independent t test and within groups by paired sample t test. BOMP improved within groups from on average 0.80 at baseline to 0.60 in the group without SLS and to 0.56 in the group with SLS. No statistical difference for BOMP, plaque and gingival abrasion was found between both groups. VAS scores for taste, freshness and foaming effect were significantly in favour of the SLS-containing dentifrice. The test dentifrice without SLS was as effective as a regular SLS dentifrice on gingival bleeding scores and plaque scores. There was no significant difference in the incidence of gingival abrasion. In patients diagnosed with gingivitis, a dentifrice without SLS seems to be equally effective compared to a dentifrice with SLS and did not demonstrate any significant difference in gingival abrasion. In patient with recurrent aphthous ulcers, the absence of SLS may even be beneficial. However, participants indicate that they appreciate the foaming effect of a dentifrice with SLS more.

  11. Report a possible correlation between necrotizing ulcerative gingivitis and mononucleosis Reporte de una posible correlación entre la gingivitis ulceronecrotizante y la mononucleosis

    OpenAIRE

    Rosa Francinne Miranda; Adriana Jou; Fábio Vieira de Miranda; Pantelis Varvaki Rados; Márcia Oliveira Gaiger; Anna Chaves Cecília Moraes

    2011-01-01

    Necrotizing ulcerative gingivitis is a relatively uncommon periodontal disease, characterized by ulceration, necrosis, pain and gingival bleeding. Factors often related to its occurrence include stress and systemic viral infections, such as those caused by cytomegalovirus and Epstein-Barr virus type 1, the latter being also considered the causative agent of infectious mononucleosis. This article aims to describe a clinical case of a female patient who presented with necrotizing ulcerative gin...

  12. Gingival margin alterations and the pre-orthodontic treatment amount of keratinized gingiva.

    Science.gov (United States)

    Closs, Luciane Quadrado; Branco, Paula; Rizzatto, Susana Deon; Raveli, Dirceu Barnabé; Rösing, Cassiano Kuchenbecker

    2007-01-01

    The purpose of this retrospective study was to associate the amount of keratinized gingiva present in adolescents prior to orthodontic treatment to the development of gingival recessions after the end of treatment. The sample consisted of the intra-oral photographs and orthodontic study models from 209 Caucasian patients with a mean age of 11.20 +/- 1.83 years on their initial records and 14.7 +/- 1.8 years on their final records. Patients were either Angle Class I or II and were submitted to non-extraction orthodontic treatment. Gingival recession was evaluated by visual inspection of the lower incisors and canines as seen in the initial and final study models and intra-oral photographs. The amount of recession was quantified using a digital caliper and the observed post-treatment gingival margin alterations were classified as unaltered, coronal migration of the gingival margin or apical migration of the gingival margin. The width of the keratinized gingiva was measured from the mucogingival line to the gingival margin on the pre-treatment photographs. The teeth that developed gingival recession and those that did not have their gingival margin position changed did not differ in relation to the initial amount of keratinized gingiva (3.00 +/- 0.61 and 3.5 +/- 0.86 mm, respectively). Paradoxically, teeth that presented a coronal migration of the gingival margin had a smaller initial amount of keratinized gingiva (2.26 +/- 0.31 mm). The mean amount of initial keratinized gingiva did not predispose lower incisors and canines to gingival recession.

  13. The association of orthodontic treatment and fixed retainers with gingival health.

    Science.gov (United States)

    Levin, Liran; Samorodnitzky-Naveh, Gili R; Machtei, Eli E

    2008-11-01

    The use of postorthodontic fixed retainers made of wire and composite resin bonded to the lingual/palatal tooth aspect is a common practice that can affect gingival health. The purpose of this study was to evaluate the association of orthodontic treatment and fixed retainers with gingival health. The study included 92 consecutive subjects who arrived for routine dental examination at a military dental clinic between May and August 2007. Plaque and gingival indices, gingival recession, probing depth, and bleeding on probing were measured at the anterior sextants. When a fixed retainer was present, the distance was measured between the retainer and incisal edge and to the cemento-enamel junction. Past orthodontic treatment and smoking habits were self-reported. Postorthodontic patients were sorted by the presence or absence of fixed retainers. The mean probing depth was 1.90 +/- 0.2 mm, and gingival recession was 0.06 +/- 0.02 mm; 20.8% of all sites exhibited bleeding on probing. Current smoking was reported by 20 (21.7%) patients. Labial gingival recession was significantly greater in treated (0.13 +/- 0.2 mm) patients compared to non-treated patients (0.05 +/- 0.2 mm; P = 0.03). Localized lingual gingival recession was significantly greater in teeth with fixed retainers (0.09 +/- 0.2 mm) compared to teeth with no fixed retainers (0.01 +/- 0.1 mm; P = 0.0002), as were plaque and gingival indices and bleeding on probing. Plaque on the lingual/palatal aspect showed a weak, positive correlation with lingual gingival recession (r = 0.16; P = 0.033). Orthodontic treatment and fixed retainers were associated with an increased incidence of gingival recession, increased plaque retention, and increased bleeding on probing; however, the magnitude of the difference in recession was of low clinical significance.

  14. Prevalence of herpesviruses in gingivitis and chronic periodontitis: relationship to clinical parameters and effect of treatment

    Directory of Open Access Journals (Sweden)

    Rucha Shah

    2016-01-01

    Full Text Available Background: Assess the prevalence of herpesviruses in healthy subjects, gingivitis, and chronic periodontitis patients, to assess the relationship between the prevalence of herpesviruses and periodontal clinical parameters, and to evaluate the effect of phase-I therapy on the level of viral detection. Materials and Methods: Hundred patients consisting of 20 healthy subjects, 40 gingivitis, and 40 chronic periodontitis were included in the study. Clinical parameters recorded included plaque index, gingival index, sulcus bleeding index, probing depth, and clinical attachment level. The gingivitis and chronic periodontitis patients received phase-I periodontal therapy including oral hygiene instructions, full mouth scaling for gingivitis patients and scaling and root planing for chronic periodontitis patients. Gingival crevicular fluid (GCF was collected, and the presence of herpes simplex virus-1 (HSV-1, HSV-2, cytomegalovirus, and Epstein–Barr virus (EBV was analyzed using polymerase chain reaction (PCR. Recording of periodontal parameters as well as GCF collection was performed at baseline and 6 weeks postphase-I therapy. Results: At baseline, the levels of HSV-1 and EBV detection were lower in healthy controls as compared to gingivitis (P < 0.05 and chronic periodontitis cases (P < 0.001. Phase-I therapy led to reduction in the amount of HSV-1 and EBV in gingivitis patients (P < 0.05 and for HSV-1, human cytomegalovirus and EBV in chronic periodontitis patients (P < 0.05 in comparison to baseline. The prevalence of EBV in chronic periodontitis patients was positively associated with increased gingival index, probing depth and loss of clinical attachment (P < 0.05. Conclusions: Higher prevalence of HSV-1 and EBV viruses in GCF of gingivitis and chronic periodontitis suggests a strong association between these viruses and periodontal diseases and periodontal therapy can lead to a reduction in herpesviruses at infected sites.

  15. Clinical and bacteriological study of the effect of Nd:YAG laser in gingivitis therapy

    Science.gov (United States)

    Colojoara, Carmen; Mavrantoni, Androniki; Miron, Mariana I.

    2000-06-01

    The relationship between dental plaque and gingivitis was verified. Nonspecific gingivitis is an inflammatory process, frequently caused by enzymes and toxins liberate by bacteria form dental plaque. Loose plaque has come under a great deal of investigation because of its role in attachment loss. The current methods used in the treatment of non specific gingivitis encompass the use of antibiotics and conventional surgical techniques. Treating gingivitis with laser energy may further reduce the gingival inflammation and decrease the wound healing time. The lack of correlation between the quantity of dental plaque and the intensity of gingivitis determined us to study the effect of Nd:YAG pulsed laser in reduction of gingival inflammation and wound healing. The aim of this work is to evaluate clinically the anti- inflammatory and wound healing effect of pulsed Nd:YAG laser and to compare the appearance and the levels of the bacteria in the supergingival and subgingival plaque in adolescents with tooth crowding after Nd:YAG laser. The experimental procedure consisted of a clinical and bacteriological study which was undertaken in 20 patients presenting moderate gingivitis. A group of 10 patients was the subject of a bacteriological study and the other group of 10 was used for clinical and histological examination. For each group the clinical criteria of evaluation were: the gingival index, papillary bleeding index, spontaneous aches. Each patient was tested before and after laser exposure or conventional therapy for bacteriological analyses. The results prove that early gingivitis exposure to laser registers a decrease of bacterial colony number and absence of loss of attachment as compared to the application of the conventional treatment. Clinical study has shown that the combination of scaling and root planning with laser therapy is enough to provide improvement in clinical indices and reduction in the number of bacterial colonies.

  16. Enhancing gingival biotype through chorion membrane with innovative step in periodontal pocket therapy.

    Science.gov (United States)

    Kothiwale, Shaila; Rathore, Amrita; Panjwani, Vishal

    2016-03-01

    A thick gingival biotype is a requisite for good periodontal health. It has important role in resisting trauma and subsequent gingival recession. The gingival thickness is a significant predictor of clinical outcome of periodontal surgeries. Various surgical procedures are used to increase the gingival thickness. The present study incorporated the innovative step of placement of chorion membrane to objectively evaluate the increase in thickness of gingival biotype during periodontal pocket therapy. The patients in age group between 25 and 45 years with chronic periodontitis, indicated for flap surgery were selected for the study. The sites with pocket depth of 6-8 mm in the mandibular anterior teeth were divided into test and control sites. Periodontal flap surgery was carried at both the sites and chorion membrane was placed at the test sites. The gingival thickness measurement was assessed using a markings marked on injection needle, these markings were read using digital vernier caliper, pre and post operatively. The baseline values of gingival thickness at test site (1.04 ± 0.19 at mid buccal region, 1.24 ± 0.20 at mid papillary) and control site (0.94 ± 0.11 at mid buccal region, 1.14 ± 0.11 at mid papillary region) showed no statistically significant difference. At test sites, 6 weeks post treatment (1.36 ± 0.16 at mid buccal region and 1.48 ± 0.17 at mid papillary region) as compared to control sites (1.06 ± 0.11 at mid buccal region, 1.24 ± 0.11 at mid papillary) showed statistically significant increase in gingival thickness (p ≤ 0.05*). The innovative step of placement of chorion membrane during periodontal pocket therapy facilitated increase in the gingival thickness in the areas with thin gingival biotype.

  17. Proliferación de células madres mesenquimales obtenidas de tejido gingival humano sobre una matriz de quitosano: estudio in vitro Proliferation of mesenchymal stem cells from human gingival tissue on chitosan scaffold: an in vitro study

    Directory of Open Access Journals (Sweden)

    B M Hernández

    2011-08-01

    Full Text Available Objetivo: Comprobar la proliferación de células madres mesenquimales (MSCs provenientes de tejido conjuntivo gingival humano sobre una matriz de quitosano. Método: Estudio experimental in vitro en el cual se aislaron MSCs a partir de cultivos por explante de tejido conjuntivo gingival. La presencia de MSCs, se caracterizó mediante citometría de flujo, utilizando para ello anticuerpos CD34, CD45, CD73, CD90, CD105, diferenciación hacia tres linajes celulares: adipocitos, osteoblastos y condroblastos. La diferenciación fue corroborada mediante microscopía óptica con tinciones Oil Red, Alizarin Red y Safranina O respectivamente. La matriz de quitosano fue analizada mediante microscopía óptica. Las MSCs en pasaje 5, fueron sembradas en presencia de la matriz de quitosano. La proliferación de las células madres fue analizada mediante microscopía óptica y tinción con cristal violeta. Resultados: A partir del explante de tejido gingival humano se obtuvieron MSCs, que cumplieron con los criterios de caracterización morfológica y fenotípica correspondiente a una MSC. Las MSC adoptaron una morfología fibroblastoide, adherencia al plástico, confluencia de un 80% y sobre un 90% expresaron los marcadores CD73, CD90 y CD105 y bajo un 10% fueron negativas para CD34, y CD45 por técnica de citometria de flujo. Las MSC cultivadas en presencia de quitosano proliferan, sin embargo observamos que a mayor concentración de quitosano en el cultivo disminuye la proliferación y densidad celular. La matriz de quitosano en presencia del medio de cultivo pierde sus propiedades físicas, disolviéndose y formando un gel no transportable. Conclusiones: A pesar de existir proliferación celular de MSCs de origen gingival humano en presencia de la matriz de quitosano, su utilidad como andamiaje y medio de transporte de MSC es deficiente debido a que se alteran sus propiedades físicas, disolviéndose y formando un gel no transportable en contacto con el

  18. Desquamative gingivitis as only presenting sign of mucous membrane pemphigoid

    Directory of Open Access Journals (Sweden)

    Veena Vijayan

    2016-01-01

    Full Text Available Desquamative gingivitis (DG is a clinical condition in which the gingiva appears reddish, glazed, and friable with loss of superficial epithelium. DG is considered a clinical manifestation of many gingival diseases and hence not identified as a diagnosis itself. Mucous membrane pemphigoid (MMP is an autoimmune vesiculobullous disorder of mucous membrane characterized by subepithelial bullae formation. MMP can affect the mucous membranes of oral cavity, conjunctiva, nasopharynx, larynx, esophagus, genitourinary tract, and anus and vary in its severity. The most commonly affected sites are oral cavity and conjunctiva. Since DG may be the early sign or only presenting sign of these conditions, most of the times, dental surgeon plays a key role in the diagnosis and prevention of the systemic complications of these diseases. We report a case of a 41-year-old male patient presented with DG. Histopathological examination revealed subepithelial clefting suggestive of MMP. The patient was treated with topical application of triamcinolone acetonide 0.1% 3–4 times a day for 1 month.

  19. Alkaline phosphatase activity in gingival crevicular fluid during canine retraction.

    Science.gov (United States)

    Batra, P; Kharbanda, Op; Duggal, R; Singh, N; Parkash, H

    2006-02-01

    The aim of the study was to investigate alkaline phosphatase activity in the gingival crevicular fluid (GCF) during orthodontic tooth movement in humans. Postgraduate orthodontic clinic. Ten female patients requiring all first premolar extractions were selected and treated with standard edgewise mechanotherapy. Canine retraction was done using 100 g sentalloy springs. Maxillary canine on one side acted as experimental site while the contralateral canine acted as control. Gingival crevicular fluid was collected from mesial and distal of canines before initiation of canine retraction (baseline), immediately after initiation of retraction, and on 1st, 7th, 14th and 21st day and the alkaline phosphatase activity was estimated. The results show significant (p alkaline phosphatase activity on the 7th, 14th and 21st day on both mesial and distal aspects of the compared experimental and control sides. The peak in enzyme activity occurred on the 14th day of initiation of retraction followed by a significant fall in activity especially on the mesial aspect. The study showed that alkaline phosphatase activity could be successfully estimated in the GCF using calorimetric estimation assay kits. The enzyme activity showed variation according to the amount of tooth movement.

  20. CEMP1 Induces Transformation in Human Gingival Fibroblasts.

    Directory of Open Access Journals (Sweden)

    Mercedes Bermúdez

    Full Text Available Cementum Protein 1 (CEMP1 is a key regulator of cementogenesis. CEMP1 promotes cell attachment, differentiation, deposition rate, composition, and morphology of hydroxyapatite crystals formed by human cementoblastic cells. Its expression is restricted to cementoblasts and progenitor cell subpopulations present in the periodontal ligament. CEMP1 transfection into non-osteogenic cells such as adult human gingival fibroblasts results in differentiation of these cells into a "mineralizing" cell phenotype. Other studies have shown evidence that CEMP1 could have a therapeutic potential for the treatment of bone defects and regeneration of other mineralized tissues. To better understand CEMP1's biological effects in vitro we investigated the consequences of its expression in human gingival fibroblasts (HGF growing in non-mineralizing media by comparing gene expression profiles. We identified several mRNAs whose expression is modified by CEMP1 induction in HGF cells. Enrichment analysis showed that several of these newly expressed genes are involved in oncogenesis. Our results suggest that CEMP1 causes the transformation of HGF and NIH3T3 cells. CEMP1 is overexpressed in cancer cell lines. We also determined that the region spanning the CEMP1 locus is commonly amplified in a variety of cancers, and finally we found significant overexpression of CEMP1 in leukemia, cervix, breast, prostate and lung cancer. Our findings suggest that CEMP1 exerts modulation of a number of cellular genes, cellular development, cellular growth, cell death, and cell cycle, and molecules associated with cancer.

  1. The influence of academic stress on gingival inflammation.

    Science.gov (United States)

    Johannsen, A; Bjurshammar, N; Gustafsson, A

    2010-02-01

    The aim of the present study was to investigate the effects of academic stress on periodontal health, in relation to inflammatory markers in gingival crevicular fluid (GCF) and cortisol in saliva. The study included 20 healthy dental hygienists (females: mean age 29.3 +/- 8.5 SD) and was conducted during a major exam period and 4 weeks later after the exams. A clinical examination was performed and GCF was collected from four sites in each subject on these two occasions. Interleukin (IL)-1beta, IL-4, IL-6, IL-10 levels were determined using Luminex 100 and cortisol amounts by radioimmunoassay (RIA (125)I). Students registered their perceived stress on a visual analogue scale (VAS). Significance of the findings was determined using paired t-test, Wilcoxon-matched pair and Spearman's rank correlations. Students had higher amounts of dental plaque (P exam period compared with after the exams. The amounts of IL-6 and IL-10 in GCF were significantly increased during the time of examinations. The median level of cortisol in saliva was also significantly raised during the exam period compared with after the exams, 20.52 nmol/l (range: 11.91-27.34) and 16.41 nmol/l (range: 10.91-24.17) respectively, P Academic stress appears to affect periodontal health, shown by more plaque accumulation, gingival inflammation and increased amounts of IL-6, IL-10 in GCF and cortisol in saliva.

  2. Retractions of the gingival margins evaluated by holographic methods

    Science.gov (United States)

    Sinescu, Cosmin; Negrutiu, Meda Lavinia; Manole, Marius; de Sabata, Aldo; Rusu, Laura-Cristina; Stratul, Stefan; Dudea, Diana; Dughir, Ciprian; Duma, Virgil-Florin

    2015-05-01

    The periodontal disease is one of the most common pathological states of the teeth and gums system. The issue is that its evaluation is a subjective one, i.e. it is based on the skills of the dental medical doctor. As for any clinical condition, a quantitative evaluation and monitoring in time of the retraction of the gingival margins is desired. This phenomenon was evaluated in this study with a holographic method by using a He-Ne laser with a power of 13 mW. The holographic system we have utilized - adapted for dentistry applications - is described. Several patients were considered in a comparative study of their state of health - regarding their oral cavity. The impressions of the maxillary dental arch were taken from a patient during his/her first visit and after a period of six months. The hologram of the first model was superposed on the model cast after the second visit. The retractions of the gingival margins could be thus evaluated three-dimensionally in every point of interest. An evaluation of the retraction has thus been made. Conclusions can thus be drawn for the clinical evaluation of the health of the teeth and gums system of each patient.

  3. Playful strategies that increase the knowledge of students on gingivitis

    Directory of Open Access Journals (Sweden)

    Melissa Katherine Sánchez-Peña

    2015-07-01

    Full Text Available The purpose of this research was to formulate and implement playful strategies to increase the level of knowledge in a group of students about gingivitis associated with bacterial plaque and its prevention, this project was developed in Pereira city at Alfonso Jaramillo Gutiérrez high school. The studio started from assuming that traditional teaching methodologies have proved to be highly ineffective and considering that playful strategies strengthen the active participation of the subject community of intervention. A qualitative approach was adopted, this methodology is characterized by its dialogic nature where beliefs, myths, prejudices and feelings are accepted as elements of analysis to produce knowledge. The research method chosen was the Action Research and teaching workshops and focus groups were used as investigation techniques. It was proved that the initial level of knowledge of these teenagers was low. Most of them were totally unfamiliar with the gingivitis associated with dental plaque and through the playful strategies they increased their knowledge, obtained meaningful learning and achieved an active participation.

  4. Herpesviruses, the missing link between gingivitis and periodontitis?

    Science.gov (United States)

    Slots, Jørgen

    2004-10-01

    Herpesviruses appear to assume a major etiopathogenic role in various types of destructive periodontal disease. Human cytomegalovirus (HCMV), Epstein-Barr virus (EBV) and HCMV-EBV co-infection are closely associated with disease-active periodontitis in juveniles and adults, with acute necrotizing ulcerative gingivitis in children, and with periodontal abscesses. In particular, HCMV reactivation in periodontitis lesions seems to be linked to advancing disease. HCMV infects periodontal monocytes/macrophages and T-lymphocytes, and EBV infects periodontal B-lymphocytes. Herpesvirus-infected inflammatory cells generate a great variety of pro-inflammatory cytokines and may possess diminished ability to defend against bacterial challenge. Herpesvirus-associated periodontal sites tend to harbor elevated levels of periodontopathic bacteria, including Dialister pneumosintes, Porphyromonas gingivalis, Tannerella forsythia, Prevotella intermedia, Prevotella nigrescens, Treponema denticola, Campylobacter rectus and Actinobacillus actinomycetemcomitans. In summary, the available data suggest that periodontitis occurs more frequently and progresses more rapidly in herpesvirus-infected than in non-infected periodontal sites. An infectious disease model based on herpesvirus-bacteria-host immune response interactions is presented to explain how a gingivitis lesion or a stable periodontal site with increased probing depth may convert into a tissue-destroying periodontitis lesion.

  5. Microarray analysis of microbiota of gingival lesions in noma patients.

    Science.gov (United States)

    Huyghe, Antoine; François, Patrice; Mombelli, Andrea; Tangomo, Manuela; Girard, Myriam; Baratti-Mayer, Denise; Bolivar, Ignacio; Pittet, Didier; Schrenzel, Jacques

    2013-01-01

    Noma (cancrum oris) is a gangrenous disease of unknown etiology affecting the maxillo-facial region of young children in extremely limited resource countries. In an attempt to better understand the microbiological events occurring during this disease, we used phylogenetic and low-density microarrays targeting the 16S rRNA gene to characterize the gingival flora of acute noma and acute necrotizing gingivitis (ANG) lesions, and compared them to healthy control subjects of the same geographical and social background. Our observations raise doubts about Fusobacterium necrophorum, a previously suspected causative agent of noma, as this species was not associated with noma lesions. Various oral pathogens were more abundant in noma lesions, notably Atopobium spp., Prevotella intermedia, Peptostreptococcus spp., Streptococcus pyogenes and Streptococcus anginosus. On the other hand, pathogens associated with periodontal diseases such as Aggregatibacter actinomycetemcomitans, Capnocytophaga spp., Porphyromonas spp. and Fusobacteriales were more abundant in healthy controls. Importantly, the overall loss of bacterial diversity observed in noma samples as well as its homology to that of ANG microbiota supports the hypothesis that ANG might be the immediate step preceding noma.

  6. Microarray analysis of microbiota of gingival lesions in noma patients.

    Directory of Open Access Journals (Sweden)

    Antoine Huyghe

    Full Text Available Noma (cancrum oris is a gangrenous disease of unknown etiology affecting the maxillo-facial region of young children in extremely limited resource countries. In an attempt to better understand the microbiological events occurring during this disease, we used phylogenetic and low-density microarrays targeting the 16S rRNA gene to characterize the gingival flora of acute noma and acute necrotizing gingivitis (ANG lesions, and compared them to healthy control subjects of the same geographical and social background. Our observations raise doubts about Fusobacterium necrophorum, a previously suspected causative agent of noma, as this species was not associated with noma lesions. Various oral pathogens were more abundant in noma lesions, notably Atopobium spp., Prevotella intermedia, Peptostreptococcus spp., Streptococcus pyogenes and Streptococcus anginosus. On the other hand, pathogens associated with periodontal diseases such as Aggregatibacter actinomycetemcomitans, Capnocytophaga spp., Porphyromonas spp. and Fusobacteriales were more abundant in healthy controls. Importantly, the overall loss of bacterial diversity observed in noma samples as well as its homology to that of ANG microbiota supports the hypothesis that ANG might be the immediate step preceding noma.

  7. Gingival enlargement in different age groups during fixed Orthodontic treatment.

    Science.gov (United States)

    Eid, Hossam A; Assiri, Hassan Ahmed M; Kandyala, Reena; Togoo, Rafi A; Turakhia, Viral S

    2014-02-01

    During fixed orthodontic therapy, adolescents tend to have higher chances of gingivitis and gingival enlargement (GE) compared to adults. A cross sectional study was undertaken to evaluate the above hypothesis, by assessing GE in patients of different age groups receiving fixed orthodontic therapy. Patients undergoing orthodontic treatment were selected by simple random sampling from the King Khalid University College of Dentistry out patient's clinic of preventive dental sciences division to form the study group. Participant's were divided into three age groups and GE was graded as 0, 1 and 2 as per the classification of the American Academy of Periodontology. Data were analyzed by using IBM SPSS version 16.0 (Statistical Package for Social Services, Chicago, IL, USA) and descriptive statistics were obtained. Differences in proportions were compared using the Chi-square test and the significance level was set at p ≤ 0.05. 62.3% (n=33) were males and 37.7% (n=20) were females. Group 1 had 21 patients (39.7%); Group 2 had 24 patients (45.3%) and Group 3 had 8 patients (15.1%).The highest frequency (48%) of GE was observed among the Group 1 age group (10-19 years). Differences in frequency of GE according to age groups were found to be statistically significant (p=0.046).Differences in GE according to the frequency of practicing oral hygiene measures were statistically significant (pdifferent age groups during fixed Orthodontic treatment. J Int Oral Health 2014;6(1):1-4.

  8. Levels of interleukin-37 in gingival crevicular fluid, saliva, or plasma in periodontal disease.

    Science.gov (United States)

    Sağlam, M; Köseoğlu, S; Savran, L; Pekbağriyanik, T; Sağlam, G; Sütçü, R

    2015-10-01

    The aim of this study was to compare the levels of levels of interleukin-37 (IL-37) in gingival crevicular fluid, saliva and plasma in patients with periodontal disease and patients with healthy periodontium and to correlate these levels with clinical parameters. Samples of gingival crevicular fluid, whole saliva and plasma were collected from systemically healthy, nonsmoker periodontally healthy controls (group 1, n = 20), gingivitis patients (group 2, n = 20) and chronic periodontitis patients (group 3, n = 20). Full-mouth clinical periodontal parameters, including probing depth, plaque index, gingival index and bleeding on probing, were also recorded. IL-37 levels in the biofluid samples were determined by ELISA. Data were tested statistically using the Kruskal-Wallis test followed by the Mann-Whitney U-test. The concentration of IL-37 in gingival crevicular fluid was significantly lower in group 3 than in groups 1 and 2 (p = 0.001), whereas the total amounts in gingival crevicular fluid samples were similar (p > 0.05). The salivary and plasma concentrations of IL-37 were similar in the study groups (p > 0.05). There were negative correlations between gingival crevicular fluid IL-37 concentrations and gingival crevicular fluid volume in all groups (p fluid IL-37 concentration and gingival index in group 3 (p fluid, or salivary or plasma concentrations of IL-37, may not be useful diagnostic markers to differentiate periodontal disease and the periodontally healthy condition. The difference in gingival crevicular fluid IL-37 concentration between the study groups may be a result of the variation in gingival crevicular fluid volume, as suggested by the negative correlation between gingival crevicular fluid volume and gingival crevicular fluid IL-37 concentration. In the light of our findings, it seems that IL-37 is not involved in periodontal disease. Further comprehensive studies may clarify this issue more clearly. © 2014 John Wiley & Sons A

  9. Nociones actuales sobre la flora microbiana del surco gingival Current notions on the microbial flora of the gingival sulcus

    Directory of Open Access Journals (Sweden)

    Tatiana Peña Ruiz

    2007-09-01

    Full Text Available La enfermedad periodontal es un problema de salud bucal a escala mundial. Con el transcurso del tiempo, el conocimiento de la gingivitis ha sufrido grandes cambios, y es hoy en día una de las enfermedades de mayor frecuencia entre los pacientes que asisten a los servicios estomatológicos. Se realiza este estudio con el objetivo de profundizar en la relación entre los microorganismos de la placa dental y la etiología de la periodontitis. La placa dental es una comunidad microbiana compleja; como consecuencia de las interacciones entre las especies, se produce un nicho ecológico que favorece el crecimiento y la supervivencia de especies proteolíticas anaerobias estrictas, así como condiciones apropiadas para el desarrollo de periodontitis.Periodontal disease is an oral health problem worldwide. In the course of time, knowledge about gingivitis has greatly changed, and today, this is one of the most frequent diseases affecting the patients going to the dentistry service. This study was aimed at delving into the relationship between the dental plaque microorganisms and the periodontitis etiology. The dental plaque constitutes a complex microbial community; the interactions among the host species give rise to an ecological niche that favors growth and survival of strictly anaerobic proteolytic species as well as to adequate conditions for the onset of periodontitis.

  10. [Connective tissue growth factors, CTGF and Cyr61 in drug-induced gingival overgrowth--an animal model].

    Science.gov (United States)

    Ciobanică, Mihaela; Cianga, Corina; Căruntu, Irina-Draga; Grigore, Georgiana; Cianga, P

    2008-01-01

    Human gingival overgrowth may occur as a side effect of chronic administration of some therapeutic agents. The mechanisms responsible for the gingival tissues lesions, fibrosis and inflamation, involve an impaired balance between the production and the degradation of type I collagen. It has been demonstrated that CCN2/CTGF, a connective tissue growth factor, is highly expressed in the gingival tissues and positively correlated with the degree of fibrosis in the drug-induced gingival overgrowth. The aim of this study was to identify the presence and localization of CCN2/CTGF and CCN1/Cyr61, members of the same molecular family, in gingival tissues of cyclosporin A- and nifedipine-treated rats, by immunohistochemistry. Staining was evaluated with light microscope and the results show cellular and extracellular CTGF in nifedipin gingival overgrowth tissues with intensity of labeling higher compared to the CsA gingival overgrowth tissues or the controls. The staining for Cyr61 shows its intracellular localization with no diference of labeling intensity between drug-induced gingival overgrowth and normal tissues. Also, we were interested in the gingival TGF-â expression in those animals. We didn't find any commercial anti-rat TGF antibody and our anti-human antibody shows no cross-reactivity with rat tissues. The data from our study sustain the involvement of CTGF and Cyr61 as growth factors in the gingival tissues and the CTGF association with drug-induced gingival overgrowth.

  11. Immunoglobulin A, G and M levels in saliva in children between 3 - 12 years of age, healthy and with gingivitis.

    Science.gov (United States)

    Romero, Mario R; Lozano, Marta L; Posada, Carolina; Rueda, Paola A; Roa, Nelly S; Rodríguez, Adriana

    2011-01-01

    The aim of this study was to measure the level of immunoglobulin A, G and M in saliva of 3- to 12-year-old children, both healthy and diagnosed with gingivitis. A sample of 177 children was selected, of whom 24 were healthy and 153 were diagnosed with gingivitis according to Loe 's index. Samples of saliva were taken and the ELISA test was applied to obtain the immunoglobulin concentrations expressed in microg/ml. A relationship was established between the immunoglobulin levels, the disease (gingival index) and Loe 's bacterial plaque index. IgG levels were higher in healthy children. In the group with gingivitis, 95.8% of the children had incipient gingivitis with a low average index of bacterial plaque (1.33). A direct correlation was found between age and gingival index, while an inverse correlation was found between age and bacterial plaque index. The analysis of the behavior of immunoglobulin according to age showed that age was only significantly correlated to IgA levels. The analysis comparing immunoglobulin levels and clinical parameters for gingivitis showed a direct correlation between gingival index and lgM The gingival index was found that to increase with the age of the subject, even though bacterial plaque decreases. It was also found that age is a better predictor of lgA level than gingival index and bacterial plaque index are; and that gingival index is a better predictor of lgM level than age and bacterial plaque index are.

  12. Severe Gingival Enlargement with Coexisting Erosive Lichen Planus in Severe Chronic Periodontitis Patient

    Directory of Open Access Journals (Sweden)

    Ambika Sharma

    2015-01-01

    Full Text Available Plaque induced gingival enlargement is most commonly seen and when encountered simultaneously with erosive lichen planus poses a challenge to the treating dentist. Prognosis of one condition may influence the prognosis of another condition. The presented case highlights the significance of proper diagnosis and the management of simultaneously occurring gingival lesions. A 49-year-old hypertensive female presented with painful enlarged bleeding and suppurating gums with burning sensation on eating food along with long-term usage of antihypertensive drug amlodipine known for its gingival enlargement effect. All these multiple factors led to diagnostic dilemma. Effective management of the gingival enlargement was done by using electrocautery to rehabilitate the functions and esthetics of the patient. Gingival condition was also complicated by the presence of coexisting lichen planus which was predominantly erosive for which topical corticosteroid, antifungal, and antimicrobial agents were prescribed. Eight-month follow-up did not show recurrence of gingival enlargement. Electrocautery is an effective tool for the gingivectomy in severe inflammatory type of gingival enlargement because of rapid postoperative hemostasis. For the management of erosive lichen planus, long-term use of topical corticosteroids is an effective approach. Maintenance of oral hygiene and regular follow-ups are essential for these conditions.

  13. Mucous membrane pemphigoid with exclusive gingival involvement: Report of a case and review of literature

    Directory of Open Access Journals (Sweden)

    Shamimul Hasan

    2012-01-01

    Full Text Available According to Sir William Osler, Mouth is the mirror of the body which reflects systemic -diseases. The oral mucosa may be affected by a variety of mucocutaneous diseases and oral lesions may occur first or very early in several mucocutaneous disorders. The erosive gingival lesions associated with vesiculobullous diseases such as lichen planus, cicatricial pemphigoid, and pemphigus vulgaris have been collectively referred to as "Desquamative gingivitis" (DG. Gingival desquamation is a clinical sign in which the gingiva appears reddish, painful, glazed and friable with destruction of the epithelium. This gingival desquamation is due to various disease processes in gingiva. The disease process may be a localized disease of gingiva or a systemic disease which manifests in the gingiva. It is important to be aware of this rare clinical entity so as to distinguish DG from plaque induced gingivitis which is an extremely common condition, easily recognized and treated daily by the dental surgeon. Accurate diagnosis and effective treatment of these lesions may greatly diminish or reverse disease progression. Here by, we present a case of mucous membrane pemphigoid presenting as gingival desquamation in a 45 year old female. Our patient presented with generalized erythematous gingiva and gingival desquamation involving the free, attached and marginal gingiva of left maxillary and mandibular dentition. However, other mucosal and skin involvement was not appreciated in the present case. Thorough history, clinical examination, histopathology and immunofluorescence studies helped us to arrive at the diagnosis of this rare sub-epithelial blistering disorder.

  14. Occurrence, extension, and severity of gingival margin alterations after orthodontic treatment.

    Science.gov (United States)

    Closs, Luciane Q; Grehs, Betina; Raveli, Dirceu Barnabe; Rösing, Cassiano Kuschenbecker

    2008-01-01

    To assess the occurrence, extension, and severity of gingival margin alterations in a sample of youth after orthodontic treatment. Records from 209 Caucasian adolescents (118 female and 91 male) before and after orthodontic treatment were selected. Patients presented a mean age at the beginning of orthodontic treatment of 11.20 ± 1.86 years and a final mean age of 14.72 ± 1.83 years. Class I and II patients with mandibular incisors and canines that were completely erupted and with spacing or crowding not exceeding 4 mm were evaluated. The presence of gingival recession on the labial surface of the mandibular anterior teeth was evaluated in intraoral photographs and casts made before and after treatment. The proportion of patients with gingival recession after treatment was statistically higher than at the beginning (Porthodontic treatment, gingival recession was not present in any of the teeth for 63.6% of the patients; in 29.2% of the patients, recession was present in at least 1 tooth. In terms of severity, the majority of affected teeth (47%) presented gingival recession less than 2 mm and in 2% more than 4 mm. It may be concluded that alterations in the gingival margin, especially gingival recession, occur in patients after orthodontic therapy, but the extent and severity of this finding are low. COPYRIGHT © 2007 BY QUINTESSENCE PUBLISHING CO, INC.

  15. Association between post-orthodontic treatment gingival margin alterations and symphysis dimensions.

    Science.gov (United States)

    Closs, Luciane Q; Bortolini, Leonardo F; dos Santos-Pinto, Ary; Rösing, Cassiano K

    2014-01-01

    Orthodontic therapy is known to be associated with the development of gingival recession. Several factors may be involved in the causal chain of this outcome, including anatomical and behavioral aspects. Among the anatomical aspects, the dimensions of the mandibular symphysis could play a predisposing role. This study evaluated the relationship between the mandibular symphysis dimensions prior to orthodontic therapy and the development of gingival recessions on the lower incisors and cuspids. Records from 189 orthodontically treated adolescents were evaluated, including radiographs, casts and intra-oral photographs. Symphysis dimensions were assessed by cephalograms. Gingival margin alterations were determined in photographs and cast models. Association between gingival margin alterations and symphysis dimensions was tested by chi-square (α=0.05). Occurrence of gingival recession increased after orthodontic therapy. No association was observed on average of symphysis dimensions and the occurrence of gingival recessions. It may be concluded that pretreatment symphysis dimensions may not be used as predictors of gingival recession after orthodontic therapy.

  16. Effect of ozonated oil and chlorhexidine gel on plaque induced gingivitis: A randomized control clinical trial

    Science.gov (United States)

    Indurkar, Maya Sanjeev; Verma, Renu

    2016-01-01

    Background: Several chemotherapeutic agents have been developed to prevent gingivitis and its progression into periodontitis. In this present study, the efficacy of ozonated oil and chlorhexidine gel was assessed and compared on plaque induced gingivitis. Aim: To evaluate the effect of ozonated oil on plaque induced gingivitis and to compare its efficacy with chlorhexidine gel. Materials and Methods: A total of 20 subjects, aged from 18 to 65 years, with plaque-induced gingivitis were selected from the outpatient Department of Periodontology, Government Dental College and Hospital, Aurangabad, for this study. They were divided randomly into the test or ozonated oil group (Group I) and the control or chlorhexidine gel group (Group II) with 10 subjects in each group. Subjects were randomly assigned to massage their gingiva thrice a day for 3 weeks with ozonated oil (test), and chlorhexidine gel (control). Plaque index and gingival index scores were recorded for the 20 subjects at baseline and after 3 weeks. Results: Ozonated oil (Group I) and chlorhexidine gel (Group II) groups showed statistically significant differences with respect to plaque index and gingival index, from the baseline to 3 weeks (P ozonated oil and chlorhexidine gel, both can be used as an effective agent in maintaining and improving gingival health. PMID:27041835

  17. Dental problems in patients with diabetes mellitus (II): gingival index and periodontal disease.

    Science.gov (United States)

    Arrieta-Blanco, Juan José; Bartolomé-Villar, Bagoña; Jiménez-Martinez, Ester; Saavedra-Vallejo, Pilar; Arrieta-Blanco, Francisco Jesús

    2003-01-01

    Among the late complications associated to the diabetes mellitus, periodontal disease has been highlighted, and it can be more severe and refractory to treatment than in healthy subjects. Determine the prevalence of gingivitis and periodontitis as well as the Community Periodontal Index of Need of Treatment (CPITN) in diabetic population compared with a control one. Analyze the histological characteristics in the gingiva of diabetic patients. The study sample was made up of 74 control subjects and 70 diabetics. We evaluated the following parameters: gingival status according to the Löe and Silness criterion, probe depth, loss of insertion, gingival recession and Community Periodontal Index of Need of Treatment. We also performed gingival biopsies in 42 diabetic patients and 29 controls for histological studies. We found a statistically higher gingivitis index, loss of insertion and gingival recession in diabetic patients compared to the control population, the same not occurring with the probe depth. We did not find significant differences in the CPITN according to the type of diabetes mellitus, metabolic control or disease duration. The biopsy study did not show significant changes in the gingiva of the diabetic patients compared to the control population. The gingivitis index was higher in the diabetic population. After examination of the treatment needs, we observed how the diabetic patients required more complex treatment.

  18. Gingival condition of women with gestational diabetes on a Greek island.

    Science.gov (United States)

    Mittas, Efthymios; Erevnidou, Katerina; Koumantakis, Evgenios; Papavasileiou, Stathis; Helidonis, Emmanuel

    2006-01-01

    The purpose of this study was to investigate the condition of gingival tissues in women who had gestational diabetes mellitus. The study group consisted of 64 women with gestational diabetes and the control group of 88 healthy pregnant women. The plaque index and gingival index and their relationship to a series of variables (socio-demographic, diet, oral hygiene, oral condition) were evaluated. Clinical evaluations were carried out between 34 and 36 weeks of pregnancy. The women with gestational diabetes had a higher mean plaque index and higher mean gingival index than the healthy pregnant women (p = 0.048 and p = 0.029, respectively). Linear regression analysis showed an association between gingival index and plaque index (p diabetes was not significantly related to gingivitis when other factors that differed between the two groups were taken into account. The results of the study suggest that gingival inflammation seems to be more prevalent in women with gestational diabetes compared to healthy pregnant women, while the plaque accumulation remains the main cause of gingival inflammation.

  19. Gingival immunologic defense index: a new indicator for evaluating dental plaque infection risk in allergic children

    Directory of Open Access Journals (Sweden)

    Seno Pradopo

    2008-03-01

    Full Text Available There is a possible relationship between dental plaque and children allergic diseases. According to literatures, gingivitis suffered mostly by allergic children than control. Case reports also revealed that dental plaque control therapy was able to reduce, even eliminate rhinosinusitis and asthmatic symptoms without additional medications. However, the exact method for confirming the gingivitis-related allergy is still uncertain. Allergic diseases have multifactorial etiologies and dental plaque had been proposed as a new trigger of allergic symptoms. Nevertheless, since not every child with gingivitis suffered from allergy or vice versa, this uncertain phenomenon may lead to patients or other clinician disbelief. The objective of the present study was to propose a new method, which involving the Gingival immunologic defense index (GIDI to evaluate the susceptibility to allergic diseases. GIDI is an index that had been developed earlier for evaluating gingival immunologic defense with respect to immunoglobulin A (IgA levels. This index based on the simple count of the inflamed gingival surfaces of a child plus the measurement of salivary IgA content. It provides clinicians with important information about the immunologic defense potential of each subject. Interestingly, most allergic children also had inherited IgA deficiency, thus this concept is likely. Based on literatures, GIDI could be a potential index for evaluating the risk of allergic diseases through gingival health assessment. However, prior investigation to the value of Indonesian GIDI index which related to allergy should be conducted.

  20. Diffuse pigmentation of maxillary attached gingiva: four cases of the cultural practice of gingival tattoo.

    Science.gov (United States)

    Rawal, Swati Y; Burrell, Renita; Hamidi, Cameron S; Kalmar, John R; Tatakis, Dimitris N

    2007-01-01

    Gingival pigmentation is a common finding, may be of endogenous or exogenous origin, and can have diagnostic significance. Diffuse gingival pigmentation may be physiologic in nature or can be due to environmental factors, drugs, endocrine disorders, or genetic conditions. We present four cases of diffuse gingival pigmentation due to traditional gingival tattooing and review the literature on this practice. Four black females (aged 19 to 56 years) of West African origin (Mauritania and Senegal), representing three different ethnic groups (Fulani, Mandinka, and Soninke) presented with various chief complaints. All exhibited diffuse pigmentation of the maxillary vestibular gingiva extending to the second premolar areas, without any associated radiographic abnormalities. The color ranged from intense blue gray to light gray or grayish pink. One case was biopsied for histopathologic evaluation. Questioning revealed that the women had had one or more sessions of traditional gingival tattooing. In one case, the procedure was performed in a dental office. The color range appeared to depend on the time that elapsed since the last procedure. The biopsy exhibited dense fibrous connective tissue containing aggregates of foreign material consistent with a foreign body tattoo. Gingival tattooing, a cultural practice prevalent in certain African ethnic groups, results in diffuse pigmentation. Outside of Africa, it may be misinterpreted as racial pigmentation or pose a diagnostic puzzle. The color and distribution pattern of diffuse gingival pigmentation often are quite suggestive, and the clinical diagnosis should be confirmed by patient history. In selected cases, biopsy may be necessary to exclude other diagnostic considerations.

  1. Dental flossing as a diagnostic method for proximal gingivitis: a validation study.

    Science.gov (United States)

    Grellmann, Alessandra Pascotini; Kantorski, Karla Zanini; Ardenghi, Thiago Machado; Moreira, Carlos Heitor Cunha; Danesi, Cristiane Cademartori; Zanatta, Fabricio Batistin

    2016-05-20

    This study evaluated the clinical diagnosis of proximal gingivitis by comparing two methods: dental flossing and the gingival bleeding index (GBI). One hundred subjects (aged at least 18 years, with 15% of positive proximal sites for GBI, without proximal attachment loss) were randomized into five evaluation protocols. Each protocol consisted of two assessments with a 10-minute interval between them: first GBI/second floss, first floss/second GBI, first GBI/second GBI, first tooth floss/second floss, and first gum floss-second floss. The dental floss was slid against the tooth surface (TF) and the gingival tissue (GF). The evaluated proximal sites should present teeth with established point of contact and probing depth ≤ 3mm. One trained and calibrated examiner performed all the assessments. The mean percentages of agreement and disagreement were calculated for the sites with gingival bleeding in both evaluation methods (GBI and flossing). The primary outcome was the percentage of disagreement between the assessments in the different protocols. The data were analyzed by one-way ANOVA, McNemar, chi-square and Tukey's post hoc tests, with a 5% significance level. When gingivitis was absent in the first assessment (negative GBI), bleeding was detected in the second assessment by TF and GF in 41.7% (p gingivitis in the second assessment (negative GBI), TF and GF detected bleeding in the first assessment in 38.9% (p = 0.004) and 58.3% (p gingivitis than GBI.

  2. Metabolic syndrome and gingival inflammation in Caucasian children with a family history of obesity.

    Science.gov (United States)

    Kâ, Khady; Rousseau, Marie-Claude; Lambert, Marie; Tremblay, Angelo; Tran, Simon D; Henderson, Mélanie; Nicolau, Belinda

    2013-11-01

    To investigate whether metabolic syndrome (MetS) and its components are associated with gingival inflammation in children. This is a cross-sectional analysis from the baseline visit of the QUebec Adipose and Lifestyle InvesTigation in Youth cohort, an ongoing longitudinal study investigating the natural history of obesity in children of Quebec, Canada. The analytic sample includes 448 children aged 8-10 years, 39% of whom were overweight or obese. MetS was defined according to the International Diabetes Federation recommendations. Gingival inflammation was defined by the level of gingival crevicular fluid (GCF) tumour necrosis factor alpha (TNF-α) and the extent of gingival bleeding. Sex-specific linear regression analyses estimated the associations between MetS and gingival inflammation, adjusting for potential confounders. Twenty-five children had MetS. Boys with MetS compared to those without, had a 49.5% (p-value = 0.001) higher GCF TNF-α level and 13.7% (p-value = 0.033) more sites with gingival bleeding. Moreover, for three of the five components of MetS - waist circumference, fasting plasma triglycerides, systolic blood pressure - an increase was associated with increased GCF TNF-α level in boys. No such findings were seen in girls. An association between MetS and gingival inflammation was observed as early as in childhood, and may differ by sex. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  3. Alport syndrome: significance of gingival biopsy in the initial diagnosis and periodontal evaluation after renal transplantation

    Directory of Open Access Journals (Sweden)

    Hilal Uslu Toygar

    2009-12-01

    Full Text Available Alport Syndrome (AS is an important hereditary disorder affecting the glomerular basement membrane. Diagnosis of AS is based on the presence of hematuric nephropathy, renal failure, hearing loss, ocular abnormalities and changes in the glomerular basement membrane of the lamina densa. The aims of this case report were to show the changes in the gingival tissues in a patient with AS under therapy with cyclosporin-A after renal transplantation and to discuss the possible role of type IV collagen in gingival basal lamina as an alternative approach for the diagnosis of AS. A 20-year-old male patient with AS underwent periodontal therapy including a series of gingivectomy surgeries. Gingival samples obtained during the second surgery were examined histopathologically and by transmission electron microscopy for further pathological examination. Gingivectomy procedures have been performed every 6 months over the last 4 years. The excessive and fibrous gingival enlargements resulted in migration of the anterior teeth, but no alveolar bone loss occurred. This is the first report to demonstrate the possible changes in the gingival tissues caused by AS. It is suggested that gingival biopsy can be an initial diagnostic tool instead of renal or skin biopsies. Proper dental and periodontal care and regular visits to the dentist could provide limited gingival hyperplasia to patients with AS.

  4. Gingival enlargement as a manifestation of tuberous sclerosis: case report and periodontal management.

    Science.gov (United States)

    Korol, Urszula B; Schoor, Robert; Nanda, Veena; Almas, Khalid; Phelan, Joan A

    2008-04-01

    Tuberous sclerosis is an autosomal-dominant inherited disease involving many organs of the body. Oral manifestations include gingival enlargement, fibromas, and dental enamel pitting. The report presents a case of tuberous sclerosis with gingival enlargement histologically consistent with angiofibroma, describes its successful periodontal management, and reviews the literature associated with oral manifestations of tuberous sclerosis. A 26-year-old white male presented to the Department of Periodontics and Implant Dentistry, New York University College of Dentistry, with a diagnosis of tuberous sclerosis and a chief complaint of gingival enlargement affecting mastication and esthetics. Following a complete medical history review, consultation with the patient's medical team at New York University Medical Center, and a thorough oral and periodontal examination, a treatment plan was developed that included oral hygiene instructions, mechanical debridement, and periodontal reevaluation. This was followed by gingivectomy, which provided improved function and esthetics. Excised tissue was submitted for histologic examination. The patient was followed every 2 months for assessment of the outcome of the surgical treatment. An extensive search of the dental and dermatologic literature was performed on MEDLINE. Histologic examination of the gingival tissue revealed features consistent with angiofibroma. Fifteen months following gingivectomy, the contours and gingival surface appearance remained normal. The gingival enlargement was histologically consistent with the characteristic angiofibromas of tuberous sclerosis. The gingival enlargement responded very well to gingivectomy and periodontal maintenance.

  5. Gingival Retraction Methods for Fabrication of Fixed Partial Denture: Literature Review

    Directory of Open Access Journals (Sweden)

    Safari S

    2016-06-01

    Full Text Available Fixed dental prosthesis success requires appropriate impression taking of the prepared finish line. This is critical in either tooth supported fixed prosthesis (crown and bridge or implant supported fixed prosthesis (solid abutment. If the prepared finish line is adjacent to the gingival sulcus, gingival retraction techniques should be used to decrease the marginal discrepancy among the restoration and the prepared abutment. Accurate marginal positioning of the restoration in the prepared finish line of the abutment is required for therapeutic, preventive and aesthetic purposes. In this article, conventional and modern methods of gingival retraction in the fixed tooth supported prosthesis and fixed implant supported prosthesis are expressed. PubMed and Google Scholar databases were searched manually for studies on gingival tissue managements prior to impression making in fixed dental prosthesis since 1975. Conclusions were extracted and summarized. Keywords were impression making, gingival retraction, cordless retraction, and implant. Gingival retraction techniques can be classified as mechanical, chemical or surgical. In this article, different gingival management techniques are discussed.

  6. Effects of herbal and non-herbal toothpastes on plaque and gingivitis: A clinical comparative study.

    Science.gov (United States)

    Tatikonda, Aravind; Debnath, Surangama; Chauhan, Vivek Singh; Chaurasia, Vishwajit Rampratap; Taranath, M; Sharma, Akanksha Manmohan

    2014-12-01

    Presence of plaque may be the culprit for dental caries, gingivitis, periodontal problems, and halitosis. Many mechanical aids are practiced worldwide to remove or control plaque, including tooth brushes, dental floss, mouth rinses, and dentifrices. The objective of this clinical study was to investigate the effectiveness of herbal toothpaste (Dabur Red) in controlling plaque and gingivitis, as compared to conventional (non-herbal) dentifrice (Pepsodent). In this study, 30 subjects aged 35-43 years with established gingivitis and at least 20 natural teeth, and having a probing depth <3 mm were investigated. After the washout period, plaque and gingival index (PI and GI, respectively) scores were assessed at days 0 and 30. Differences between groups were compared with Mann-Whitney U test and the mean scores of PI and GI by Wilcoxon test. Statistical difference between the weights of dentifrices tubes on days 0 and 30 was evaluated by Student's t-test. At the end of 30 days of the study, there was statistically significant difference between both the groups for plaque and gingival scores. After 30 days of trial, both test and control groups showed effective reduction of plaque and gingivitis, which was statistically significant. No adverse reactions to dentifrices products were observed during the trial. It was concluded that herbal dentifrice was as effective as non-herbal dentifrices in the control of plaque and gingivitis.

  7. Analysis of mutations in the SOS-1 gene in two Polish families with hereditary gingival fibromatosis.

    Science.gov (United States)

    Gawron, K; Bereta, G; Nowakowska, Z; Łazarz-Bartyzel, K; Potempa, J; Chomyszyn-Gajewska, M; Górska, R; Plakwicz, P

    2017-10-01

    To establish whether two families from Malopolska and Mazovia provinces in Poland are affected by hereditary gingival fibromatosis type 1, caused by a single-cytosine insertion in exon 21 of the Son-of-Sevenless-1 gene. Six subjects with hereditary gingival fibromatosis and five healthy subjects were enrolled in the study. Gingival biopsies were collected during gingivectomy or tooth extraction and used for histopathological evaluation. Total RNA and genomic DNA were purified from cultured gingival fibroblasts followed by cDNA and genomic DNA sequencing and analysis. Hereditary gingival fibromatosis was confirmed by periodontal examination, X-ray, and laboratory tests. Histopathological evaluation showed hyperplastic epithelium, numerous collagen bundles, and abundant-to-moderate fibroblasts in subepithelial and connective tissue. Sequencing of exons 19-22 of the Son-of-Sevenless-1 gene did not reveal a single-cytosine insertion nor other mutations. Patients from two Polish families under study had not been affected by hereditary gingival fibromatosis type 1, caused by a single-cytosine insertion in exon 21 of the Son-of-Sevenless-1 gene. Further studies of the remaining regions of this gene as well as of other genes are needed to identify disease-related mutations in these patients. This will help to unravel the pathogenic mechanism of gingival overgrowth. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. All rights reserved.

  8. The Differential Diagnosis of Desquamative Gingivitis: Review of the Literature and Clinical Guide for Dental Undergraduates.

    Science.gov (United States)

    Al-Abeedi, Faris; Aldahish, Yaser; Almotawa, Zaid; Kujan, Omar

    2015-01-01

    Desquamative gingivitis is an elucidating term used to demonstrate epithelial desquamation, erythema, erosions, and/or vesiculobullous lesions of the gingiva. Detection and differentiation between conditions that manifest desquamative gingivitis have been almost a continuing problem for dental undergraduates. Several studies have described the association between desquamative gingivitis and other relevant conditions. This study aimed to review the current literature on desquamative gingivitis and to formulate a clinical guide for the differential diagnosis of desquamative gingivitis designated as a teaching aid tool for dental undergraduates. A search strategy based on the key words "desquamative gingivitis, guidelines, diagnosis, undergraduate, teaching" was performed in Medline and Google Scholar. Papers published between 1932 and December 2014 were scrutinized. Only articles that describe the terminology and classification of DG-associated disorders or the diagnostic procedures of DG were selected, then obtained in full text and analyzed. 47 studies were included and reviewed narratively. The clinical signs and symptoms of desquamative gingivitis are insufficient to make a definitive diagnosis. We proposed a clinical flowchart aimed to help dental undergraduates achieving their goal in making an accurate and easy diagnosis. However, this guideline needs further evaluation.

  9. In vitro evaluation of the human gingival fibroblast/gingival mesenchymal stem cell dynamics through perforated guided tissue membranes: cell migration, proliferation and membrane stiffness assay.

    Science.gov (United States)

    Gamal, A Y; Al-Berry, N N; Hassan, A A; Rashed, L A; Iacono, V J

    2017-06-01

    Migration of gingival fibroblasts/gingival mesenchymal stem cells through macro-perforated barrier membranes may allow them to participate positively in periodontal regeneration. The optimal guided tissue membrane perforation diameter that could favor maximum cell migration into the defect area and at the same time act as an occlusive barrier for gingival epithelium and its associated gingival extracellular matrix component is not yet identified. Cultured human gingival fibroblasts/gingival mesenchymal stem cells were placed in the upper chambers of 12-well collagen-coated polytetrafluoroethylene transwells, which were manually perforated with 0.2, 0.4 and 0.7 mm sized pores. The lower chambers of the transwells received blood clot as an attraction medium. The number of cells that have migrated to the lower chambers was calculated. Proliferation of these cells was evaluated using MTT assay. Scanning electron microscopy images were obtained for the lower surfaces of the transwell membranes. Perforated bovine collagen membranes (Tutopatch(®) ) were subjected to mechanical testing to determine the tensile strength and modulus of elasticity. Group 3 (0.7 mm) showed significantly higher values for cell migration and proliferation. All groups showed a small degree of extracellular matrix migration through membrane perforations. Scanning electron microscopy evaluation revealed variable numbers of cells in fibrin matrices located mainly around the pore edges. There were non-significant differences between groups regarding mechanical properties. The present study demonstrated that macro-membrane perforations of 0.2, 0.4 and 0.7 mm are suitable pore diameters that could maintain membrane stiffness and allow for cellular migration. However, these membrane perforation diameters did not allow for total gingival connective tissue isolation. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  10. The Effect of Parenting Practices on the Severity of Gingival Bleeding in Children.

    Science.gov (United States)

    Kumar, Santhosh; Tadakamadla, Jyothi; Zimmer-Gembeck, Melanie; Kroon, Jeroen; Lalloo, Ratilal; Johnson, Newell W

    2017-08-01

    Studies have consistently reported that parenting practices have an impact on eating styles which determine obesity levels in children. However, to the best knowledge of the authors, there is no study that evaluates the association of parenting practices on gingivitis in children using path analysis to evaluate if oral health-related behavior mediates this association. This study aims to test a model of parenting and family demographic factors that could account for gingivitis in children, with a focus on the mediational roles of oral health-related behaviors and oral hygiene status. Clinical examination of oral hygiene status and gingivitis was conducted using simplified oral hygiene and modified Community Periodontal Indices, respectively, on sixth-grade school children (n = 1,539) of Medak District in Telangana State, India. Children also answered a questionnaire consisting of five closed-ended questions on oral health-related behavior. Parents responded to queries related to socioeconomic status (SES), family structure, number of children, oral health-related behavior, and parenting practices. Prevalence of gingival bleeding was 92.4%. Power assertion parenting (representing coercive or controlling parenting practices) had a negative effect on oral hygiene status (β = 0.044; P = 0.07), and also had an indirect effect on gingival bleeding (β = 0.011; P = 0.05). Oral hygiene status was positively associated with the extent of gingival bleeding (β = 0.24; P = 0.01). Children living in families with lower SES had worse oral hygiene (β = -0.101; P = 0.01) and gingival bleeding status (β = -0.024; P = 0.01). Power assertion parenting had a deleterious effect on the extent of gingival bleeding via a worse oral hygiene status of children, but SES was also important for predicting oral hygiene and gingival bleeding.

  11. Gingival biotype assessment in the esthetic zone: visual versus direct measurement.

    Science.gov (United States)

    Kan, Joseph Y K; Morimoto, Taichiro; Rungcharassaeng, Kitichai; Roe, Phillip; Smith, Dennis H

    2010-06-01

    This study evaluated the reliability of assessing visually the facial gingival biotype of maxillary anterior teeth with and without the use of a periodontal probe in comparison with direct measurements. Forty-eight patients (20 men, 28 women) with a single failing maxillary anterior tooth participated in this study. Three methods were used to evaluate the thickness of the gingival biotype of the failing tooth: visual, periodontal probing, and direct measurement. Prior to extraction, the gingival biotype was identified as either thick or thin via visual assessment and assessment with a periodontal probe. After tooth extraction, direct measurement of the gingival thickness was performed to the nearest 0.1 mm using a tension-free caliper. The gingival biotype was considered thin if the measurement was =or1.0 mm. The assessment methods were compared using the McNemar test at a significance level of a=.05. The mean gingival thickness obtained from direct measurements was 1.06+/-0.27 mm, with an equal distribution (50%) of sites with gingival thicknesses of =or1 mm. The McNemar test showed a statistically significant difference when comparing the visual assessment with assessment using a periodontal probe (P=.0117) and direct measurement (P=.0001). However, there was no statistically significant difference when comparing assessment with a periodontal probe and direct measurement (P=.146). Assessment with a periodontal probe is an adequately reliable and objective method in evaluating gingival biotype, whereas visual assessment of the gingival biotype by itself is not sufficiently reliable compared to direct measurement.

  12. TGF-β1 gene polymorphism in renal transplant patients with and without gingival overgrowth.

    Science.gov (United States)

    Kozak, M; Kurzawski, M; Wajda, A; Lapczuk, J; Lipski, M; Dziewanowski, K; Drozdzik, M

    2011-05-01

    The incidence of gingival overgrowth among renal transplant patients treated with cyclosporine A ranges from 13% to 84.6%, and the overgrowth is not only esthetic but also a medical problem. We studied the determination of association between TGF-β1 (TGFB1) gene polymorphism and gingival overgrowth in kidney transplant patients medicated with cyclosporin A. Eighty-four kidney transplant patients with gingival overgrowth and 140 control transplant patients without overgrowth were enrolled into the case control study. TGFB1 polymorphism was determined using the PCR-RFLP assay for +869T > C in codon 10 and +915G > C in codon 25 as well as TaqMan real-time PCR assays for promoter -800G>A and -509C > T SNPs. In kidney transplant patients suffering from gingival overgrowth, mean score of gingival overgrowth was 1.38 ± 0.60, whereas in control subjects it was 0.0. The patients with gingival overgrowth were characterized by similar distribution of TGFB1 genotypes and allele in comparison to subjects without gingival overgrowth. Among 16 potentially possible haplotypes of TGFB1 gene, only four were observed in the studied sample of kidney transplant patients: G_C_T_G, G_T_C_G, G_C_C_C, and A_C_T_G, with similar frequency in patients with and without gingival overgrowth. No association between the TGFB1 gene polymorphism and gingival overgrowth was revealed in kidney transplant patients administered cyclosporine A. © 2011 John Wiley & Sons A/S.

  13. Profundidad del surco gingival en dientes primarios restaurados con coronas de acero cromo

    Directory of Open Access Journals (Sweden)

    Rubén Muñoz Delgado

    2015-01-01

    Full Text Available Objetivo: Evaluar la relación entre el ajuste marginal y la profundidad del surco gingival en dientes primarios restaurados con coronas de acero cromo. Métodos: Se midió la profundidad del surco gingival de 114 dientes primarios restaurados con coronas de acero cromo en 67 niños, ambos sexos, de 3 a 6 años de edad de la clínica de Estomatología Pediátrica de la UATx, México. La población en estudio fue dividida en tres grupos: a experimental (n=30, b control (n=8, y c control negativo (n=29. Previo consentimiento informado se tomaron los índices de placa (LöeSilness 1967 e índice gingival en seis superficies; se midió el surco gingival con sonda periodontal y las coronas de acero cromo fueron evaluadas clínica y radiográficamente según su ajuste marginal y longitud cervical. Resultados: Los índices de placa y gingival no mostraron diferencias significativas para los grupos experimental y control negativo. El 34% de las coronas mostraron buen ajuste marginal, 33% un mal ajuste, 10.5% cortas, 7.9% largas y el 14% otro tipo de mal ajuste. La profundidad del surco gingival fue estadísticamente significativa para el primer y segundo molar inferior derechos y en los caninos inferiores (p >0.05; la superficie disto-vestibular presentó la mayor profundidad del surco gingival (2.34 mm, siendo estadísticamente significativa (p>0.05. Conclusiones: La profundidad del surco gingival fue mayor en los dientes rehabilitados con coronas de acero cromo mal ajustadas y sobre contorneadas (largas. La presencia de placa bacteriana y gingivitis estuvo relacionada con las coronas de acero cromo mal ajustadas.

  14. The method of diagnosis and classification of the gingival line defects of the teeth hard tissues

    Directory of Open Access Journals (Sweden)

    Olena Bulbuk

    2017-06-01

    Full Text Available For solving the problem of diagnosis and treatment of hard tissue defects the significant role belongs to the choice of tactics for dental treatment of hard tissue defects located in the gingival line of any tooth. This work aims to study the problems of diagnosis and classification of gingival line defects of the teeth hard tissues. That will contribute to the objectification of differentiated diagnostic and therapeutic approaches in the dental treatment of various clinical variants of these defects localization. The objective of the study – is to develop the anatomical-functional classification for differentiated estimation of hard tissue defects in the gingival part, as the basis for the application of differential diagnostic-therapeutic approaches to the dental treatment of hard tissue defects disposed in the gingival part of any tooth. Materials and methods of investigation: There was conducted the examination of 48 patients with hard tissue defects located in the gingival part of any tooth. To assess the magnitude of gingival line destruction the periodontal probe and X-ray examination were used. Results. The result of the performed research the classification of the gingival line defects of the hard tissues was offered using exponent power. The value of this indicator is equal to an integer number expressed in millimeters of distance from the epithelial attachment to the cavity’s bottom of defect. Conclusions. The proposed classification fills an obvious gap in academic representations about hard tissue defects located in the gingival part of any tooth. Also it offers the prospects of consensus on differentiated diagnostic-therapeutic approaches in different clinical variants of location.  This classification builds methodological “bridge of continuity” between therapeutic and prosthetic dentistry in the field of treatment of the gingival line defects of dental hard tissues.

  15. Gingival enlargement in different age groups during fixed Orthodontic treatment

    Science.gov (United States)

    Eid, Hossam A; Assiri, Hassan Ahmed M; Kandyala, Reena; Togoo, Rafi A; Turakhia, Viral S

    2014-01-01

    Background: During fixed orthodontic therapy, adolescents tend to have higher chances of gingivitis and gingival enlargement (GE) compared to adults. A cross sectional study was undertaken to evaluate the above hypothesis, by assessing GE in patients of different age groups receiving fixed orthodontic therapy. Materials & Methods: Patients undergoing orthodontic treatment were selected by simple random sampling from the King Khalid University College of Dentistry out patient’s clinic of preventive dental sciences division to form the study group. Participant’s were divided into three age groups and GE was graded as 0, 1 and 2 as per the classification of the American Academy of Periodontology. Data were analyzed by using IBM SPSS version 16.0 (Statistical Package for Social Services, Chicago, IL, USA) and descriptive statistics were obtained. Differences in proportions were compared using the Chi-square test and the significance level was set at p ≤ 0.05. Results: 62.3% (n=33) were males and 37.7% (n=20) were females. Group 1 had 21 patients (39.7%); Group 2 had 24 patients (45.3%) and Group 3 had 8 patients (15.1%).The highest frequency (48%) of GE was observed among the Group 1 age group (10-19 years). Differences in frequency of GE according to age groups were found to be statistically significant (p=0.046).Differences in GE according to the frequency of practicing oral hygiene measures were statistically significant (p<0.001). Conclusion: Highest frequency of GE was observed among the adolescents. The patients who practiced oral hygiene measures more than three times daily did not have any GE. On the other hand, those who brushed and flossed only once daily had the highest percentage of grade 2 GE. How to cite the article: Eid HA, Assiri HA, Kandyala R, Togoo RA, Turakhia VS. Gingival enlargement in different age groups during fixed Orthodontic treatment. J Int Oral Health 2014;6(1):1-4. PMID:24653595

  16. Clareamento gengival: ensino e etnocentrismo Gingival bleaching: teaching and ethnocentrism

    Directory of Open Access Journals (Sweden)

    Edson Daruich Bolla

    2010-06-01

    Full Text Available O estudo objetivou identificar os padrões de estética bucal/gengival subjacentes à formação e prática profissional do cirurgião-dentista, na perspectiva do etnocentrismo. A partir da análise documental e da realização de entrevistas (semiestruturadas com cirurgiões dentistas formados há dez ou mais anos, o estudo recorreu a uma abordagem qualitativa, ancorada na análise temática. No âmbito do ensino da periodontia, o estudo evidenciou que a presença da pigmentação fisiológica é omitida ou tratada como uma alteração de normalidade e/ou antiestética. Todos os entrevistados aprenderam a realizar o clareamento gengival em nível de pós-graduação, sendo estimulados a ofertar tal procedimento em nome de um sorriso saudável e bonito. Diante da supervalorização da eficiência da técnica, ressalta a ausência da discussão da questão estética na perspectiva étnica. Parece que a oferta do clareamento gengival se faz norteada pelo padrão branco de beleza, evidenciando o caráter etnocêntrico do procedimento.The aim of this study was to identify buccal/gingival cosmetic dentistry patterns subjacent to formation and professional practice of the dental surgeon from the ethnocentrism point of view. This is an exploratory study with a qualitative approach based on the thematic analysis. Initially a documental analysis was carried out. Thereafter, dental surgeons were interviewed and semi-structured questions were applied. In the Periodontal teaching field, this study showed that the presence of racial melanosis is omitted or treated as an alteration in the normality patterns and it is considered anti-aesthetic. All the interviewers learnt how to practice gingival bleaching in the post-graduation courses, they were all encouraged to offer this cosmetic dentistry procedure with the opportunity of obtaining a beautiful and healthy smile, thus assuring the belief of the Caucasian racial aesthetic superiority. This study make us

  17. Estudio clínico comparativo entre colutorio de p-clorofenol y peróxido de hidrógeno con colutorio de clorhexidina al 0.12% en el crecimiento de placa microbiana y gingivitis Mouthwash comparative study between p-chlorophenol and hydrogen peroxide with chlorhexidine mouthwash 0.12% in the growth of microbial plaque and gingivitis

    Directory of Open Access Journals (Sweden)

    PD Jaña

    2010-08-01

    Full Text Available Se formuló un colutorio a base de p-clorofenol alcanforado y peróxido de hidrógeno, y considerando que no se disponían de antecedentes de eficacia y seguridad del colutorio, se realizó un ensayo clínico para medirlas utilizando un modelo de formación de placa microbiana y gingivitis en un período de cuatro días, como control positivo se uso un colutorio de clorhexidina al 0.12%. Participaron 26 sujetos en un estudio doble ciego cruzado y con distribución aleatoria. El colutorio en base a p-clorofenol alcanforado y peróxido de hidrógeno y el de clorhexidina tuvieron un similar efecto en el control de la formación de placa y antigingivitis. No hubo diferencias entre los acontecimientos adversos observados para el colutorio y el control. Por consiguiente, el colutorio en estudio podría ser una alternativa para el control químico de la placa microbiana y gingivitis en el tratamiento de la enfermedad periodontal.A camphorated p-chlorophenol and hydrogen peroxide-based mouthwash was prepared, and a clinical trial to measure the efficiency and safety records of the mouthwash -considering the lack of them- was carried out using a formation model of microbial plaque and gingivitis over a 4-day period, with a 0.12% chlorhexidine mouthwash as positive control. Twenty-six individuals participated in the randomized double-blind crossover study. The camphorated p-chlorophenol and hydrogen peroxide-based and chlorhexidine mouthwash had a similar effect in controlling the formation of plaque and antigingivitis. There was no difference between the adverse events observed for the mouthwash and the control. Therefore, the mouthwash in study might be an alternative to the chemical control of microbial plaque and gingivitis in the periodontal desease treatment.

  18. Infecciones genitales por VPH tratadas por microinmunoterapia

    National Research Council Canada - National Science Library

    Jacques Grauwet, Diego

    2011-01-01

    ... genitales por VPH tratadas por microinmunoterapia Diego Jacques Grauwet Médico ginecólogo y homeópata, Madrid, España Recibido el 30 de mayo de 2010; aceptado el 10 de septiembre de 2011 Correo...

  19. Using saliva nitrite and nitrate levels as a biomarker for drug induced gingival overgrowth

    Directory of Open Access Journals (Sweden)

    Erkan eSukuroglu

    2015-12-01

    Full Text Available Aim: Drug-induced gingival overgrowth has a multifactorial nature and the pathogenesis is still uncertain. It has been suggested that Nitric Oxide (NO might play a role in the pathogenesis of drug-induced gingival overgrowth due to the contribution of NO to immune response and matrix degradation. NO levels in biological fluids have been used as a diagnostic biomarker in many diseases. The aim of this study is to determine whether NO levels in plasma, saliva and gingival crevicular fluid (GCF can serve as a potential biomarker for the evaluation of drug-induced gingival overgrowth risk. Material and Methods: A total of 104 patients, receiving cyclosporine A (n=35, phenytoin (n=25, nifedipine (n=26 or diltiazem (n=18 participated in the study. The amount of gingival overgrowth was evaluated with two indices and was given as percentage. Periodontal clinical parameters including plaque index (PI, gingival index (GI, gingival bleeding time index (GBTI and probing depth (PD were also assessed. Saliva, GCF and plasma samples were obtained from each participants. Nitrite and nitrate levels in saliva, GCF and plasma were analyzed by Griess reagent. Results: Salivary nitrite and nitrate levels in responders were significantly higher than those in non-responders in only phenytoin group (p˂0.05. Nitrite and nitrate levels of gingival crevicular fluid and plasma did not significantly differ between responders and non-responders in all study groups (p˃0.05. Salivary nitrite levels exhibited a significant correlation with PD, GBTI, severity of gingival overgrowth (%GO and GCF volume (p˂0.05. Additionally, a strong positive correlation was detected between saliva and plasma nitrate levels (p˂0.005. However, both nitrite and nitrate levels in GCF and plasma demonstrated no significant correlation with clinical parameters, GO severity and GCF volume (p˃0.05.Conclusion: Salivary nitrite and nitrate levels could be used as periodontal disease biomarkers in

  20. [B-cellular lymphoid follicles of gingival mucous membrane in cases of chronic apical periodontitis].

    Science.gov (United States)

    Maiborodin, I V; Voitovich, A B; Kozlova, E V; Kolmakova, I A; Pritchina, I A

    2009-01-01

    The structure of gingival mucous membrane leukocytal infiltration of 80 patients with chronic apical periodontitis of different age groups was studied by the light microscopy with the use of monoclonal antibodies to CD38. It was disclosed that in gingival tissues of practically all patients 2 types of leukocytal infiltration were present with low number of plasmatic cells and high number of neutrophils (true leukocytal infiltration) and structures with high number of plasmatic cells and low number of neutrophils - most likely lymphoid follicle resultant in mucous membranes of different organs in cases of chronic inflammation. In epithelial gingival paving in cases of chronic apical periodontitis CD38(+)-cells were absent.