WorldWideScience

Sample records for himalayas selection potential

  1. Permafrost in the Himalayas: specific characteristics, evolution vs. climate change and impacts on potential natural hazards

    Science.gov (United States)

    Fort, Monique

    2015-04-01

    Mountain environments are very sensitive to climate change, yet assessing the potential impacts of these changes is not easy because of the complexity and diversity of mountain systems. The Himalayan permafrost belt presents three main specificities: (1) it develops in a geodynamically active mountain, which means that the controlling factors are not only temperature but also seismo-tectonic activity; (2) due to the steepness of the southern flank of the Greater Himalaya and potential large scale rock failures, permafrost evidence manifests itself best in the inner valleys and on the northern, arid side of the Himalayas (elevations >4000m); (3) the east-west strike of the mountain range creates large spatial discontinuity in the "cold" belt, mostly related to precipitation nature and availability. Only limited studies have been carried to date, and there is no permanent "field laboratory", nor continuous records but a few local studies. Based on preliminary observations in the Nepal Himalayas (mostly in Mustang and Dolpo districts), and Indian Ladakh, we present the main features indicating the existence of permafrost (either continuous or discontinuous). Rock-glaciers are quite well represented, though their presence may be interpreted as a combined result from both ground ice and large rock collapse. The precise altitudinal zonation of permafrost belt (specifying potential permafrost, probable permafrost, observed permafrost belts) still requires careful investigations in selected areas. Several questions arise when considering the evolution of permafrost in a context of climate change, with its impacts on the development of potential natural hazards that may affect the mountain population. Firstly, permafrost degradation (ground ice melting) is a cause of mountain slope destabilization. When the steep catchments are developed in frost/water sensitive bedrock (shales and marls) and extend to high elevations (as observed in Mustang or Dolpo), it would supply more

  2. Meiotic studies in some selected angiosperms from the Kashmir Himalayas

    Institute of Scientific and Technical Information of China (English)

    Syed Mudassir JEELANI; Santosh KUMARI; Raghbir Chand GUPTA

    2012-01-01

    As a part of our program to explore and evaluate genetic diversity of flowering plants of the Kashmir Himalayas,meiotic studies have been carried out on 150 wild species.Of these,Caltha alba (2n =32),Delphinium roylei (2n =16),D.uncinatum (2n =16),Ranunculus palmatifidus (2n =28),and Sedum heterodontum (2n =14) have been cytologically worked out for the first time.New intraspecific diploid or polyploid cytotypes have been recorded for Alchemilla vulgaris (2n =34,96),Arabis amplexicaulis (2n =16),Impatiens amphorata (2n =14),Ⅰ.racemosa (2n =12),Ⅰ.sutcata (2n =16,12),Meconopsis latifolia (2n =14),Potentilla supina (2n =14),Saxifraga cernua (2n =16),Sium latijugam (2n =24),and Vicatia coniifolia (2n =44).Four species,Arabidopsis thaliana (2n =10),Berberis vulgaris (2n =28),Potentilla nubicola (2n =14),and P.sericea (2n =28),have been cytologically reported for the first time from India.A large number of meiotic abnormalities have been observed in most of these species,leading to a reduction in pollen fertility and production of heterogeneous-sized pollen grains.

  3. Hot springs and the geothermal energy potential of Jammu & Kashmir State, N.W. Himalaya, India

    Science.gov (United States)

    Craig, J.; Absar, A.; Bhat, G.; Cadel, G.; Hafiz, M.; Hakhoo, N.; Kashkari, R.; Moore, J.; Ricchiuto, T. E.; Thurow, J.; Thusu, B.

    2013-11-01

    India has an estimated geothermal power potential of 10,600 MWe, but this potential is entirely undeveloped at present. The 'Geothermal Atlas of India' prepared by the Geological Survey of India (GSI) in 1991 describes some 340 hot spring sites and identifies more than 300 sites with geothermal potential in at least seven key geothermal provinces throughout India. There are more than 20 hot spring sites in Jammu & Kashmir State, mainly in the Chenab Valley in the Lesser/Central Himalaya, the Kashmir Valley and in the High Himalaya region of Ladakh. At least three localities in the Ladakh region - Chamuthang and Puga in the Indus valley and Panamik in the Nubra Valley - are considered to have geothermal power generation potential of between 3 and > 20 MWe.

  4. Hazard Assessment of Glacial Lake Outburst Flood and Potential of ICTs for Coping: A Case of Eastern Himalaya of Nepal

    Science.gov (United States)

    Bhattarai, D. R.

    2015-12-01

    Retreat of glaciers and formation of glacial lakes in Nepal Himalaya have been reported to be related with the temperature rise in the region. Glacier Lake Outburst Floods (GLOF) are the growing climate induced hazards in the Himalaya. GLOF has increased the vulnerability of community and fragile ecosystem in the mountain valleys. This study has analyzed the potential impacts from GLOF in the highland of eastern Nepal and the potential role of Information Communication Technologies (ICT) to cope with such impacts. I analyzed the trend of climatic pattern (temperature and precipitation) of the Eastern Himalaya Region of Nepal available from the Department of Hydrology and Meteorology, Government of Nepal, and prepared the latest location map of the glacial lakes using google earth and ArcGIS applications in the highland of the Kanchanjungha Conservation Area of the region. Tiptala glacial lake, located at an elevation of 4950 m, within the conservation area, was selected for the GLOF hazard assessment. I used semi-structured questionnaire survey and key informants' interviews in the community in order to assess the potential hazard of GLOF. With the varying sizes, 46 glacial lakes were located in the region, which covers over 2.57 sq. km in total. Though the larger portion of the downstream area of the Tiptala glacial lake fall in the remote location away from major residential area, few villages, major pasture lands for Yaks, foot trails, and several bridges across the Tamor River below the lake are in risk of GLOF. Poor access due to extreme geographical remoteness and capacity to afford the modern technologies in the community are the major limiting factor to the knowledge and information about the climate change and related impacts. Modern ICTs has high potential to reduce the risk of climate related hazards in the remote area by information dissemination and awareness.

  5. Describing earthquakes potential through mountain building processes: an example within Nepal Himalaya

    Science.gov (United States)

    Zhang, Zhen; Zhang, Huai; Shi, Yaolin; Mary, Baptiste; Wang, Liangshu

    2016-04-01

    portion rupturing in Sub-Himalaya is mainly great Himalaya earthquakes (M>8), with enough energy to rupture the whole MHT, while the thrusting family 2 and 3 will cause mainly large earthquakes. The averaged lifespan of single segment (inclined short lines) is growing from the deformation front to the hinterland, while the occurrence frequency is just in the opposite way. Thrusting slips in family 1-3 will enhance the coulomb wedge development resulting in mountain building. Note that, all the large earthquake behaviors described in this paper is a statistical characteristic, just the tendency distribution on the MHT in one interval. Although our research domain is a section of the Nepal Himalaya, the treatment proposed in this paper has universality in continental collisional orogenic belt which having the same interseismic pattern. We also summary the differences of seismogenic zones in oceanic subduction zone (Cascadia subduction zone) and arc-continental subduction zone (Taiwan area). The different types of interseismic pattern(mechanical patterns) are the controlling factors controlling seismic potential on megathrust and thus impacting the mountain building history.

  6. Carbon Stock Potential of Oak and Pine Forests in Garhwal Region in Indian Central Himalayas

    Directory of Open Access Journals (Sweden)

    Nanda Nautiyal

    2013-05-01

    Full Text Available Oak (Quercus leucotichophora and pine (Pinus roxburghii are the two most dominant forest types occurring in Indian Central Himalayas. CO2 mitigation potential of these two forest types was observed in the present study. Carbon stock densities for AGTB, BB, LHG, DWS, AGSB and SOC were estimated and higher values were recorded in oak forest stands. Total carbon density estimated was 2420.54 Mg/ha for oak forest of Gopeshwar and 986.93 Mg/ha for pine forest of Nandprayag. CO2 mitigation potential of oak forest of Gopeshwar was recorded to be 8,713.94 CO2e and of pine forests 3552.95 CO2e.

  7. Impact of climate change on potential distribution of Chinese caterpillar fungus (Ophiocordyceps sinensis in Nepal Himalaya.

    Directory of Open Access Journals (Sweden)

    Uttam Babu Shrestha

    Full Text Available Climate change has already impacted ecosystems and species and substantial impacts of climate change in the future are expected. Species distribution modeling is widely used to map the current potential distribution of species as well as to model the impact of future climate change on distribution of species. Mapping current distribution is useful for conservation planning and understanding the change in distribution impacted by climate change is important for mitigation of future biodiversity losses. However, the current distribution of Chinese caterpillar fungus, a flagship species of the Himalaya with very high economic value, is unknown. Nor do we know the potential changes in suitable habitat of Chinese caterpillar fungus caused by future climate change. We used MaxEnt modeling to predict current distribution and changes in the future distributions of Chinese caterpillar fungus in three future climate change trajectories based on representative concentration pathways (RCPs: RCP 2.6, RCP 4.5, and RCP 6.0 in three different time periods (2030, 2050, and 2070 using species occurrence points, bioclimatic variables, and altitude. About 6.02% (8,989 km2 area of the Nepal Himalaya is suitable for Chinese caterpillar fungus habitat. Our model showed that across all future climate change trajectories over three different time periods, the area of predicted suitable habitat of Chinese caterpillar fungus would expand, with 0.11-4.87% expansion over current suitable habitat. Depending upon the representative concentration pathways, we observed both increase and decrease in average elevation of the suitable habitat range of the species.

  8. Impact of climate change on potential distribution of Chinese caterpillar fungus (Ophiocordyceps sinensis) in Nepal Himalaya.

    Science.gov (United States)

    Shrestha, Uttam Babu; Bawa, Kamaljit S

    2014-01-01

    Climate change has already impacted ecosystems and species and substantial impacts of climate change in the future are expected. Species distribution modeling is widely used to map the current potential distribution of species as well as to model the impact of future climate change on distribution of species. Mapping current distribution is useful for conservation planning and understanding the change in distribution impacted by climate change is important for mitigation of future biodiversity losses. However, the current distribution of Chinese caterpillar fungus, a flagship species of the Himalaya with very high economic value, is unknown. Nor do we know the potential changes in suitable habitat of Chinese caterpillar fungus caused by future climate change. We used MaxEnt modeling to predict current distribution and changes in the future distributions of Chinese caterpillar fungus in three future climate change trajectories based on representative concentration pathways (RCPs: RCP 2.6, RCP 4.5, and RCP 6.0) in three different time periods (2030, 2050, and 2070) using species occurrence points, bioclimatic variables, and altitude. About 6.02% (8,989 km2) area of the Nepal Himalaya is suitable for Chinese caterpillar fungus habitat. Our model showed that across all future climate change trajectories over three different time periods, the area of predicted suitable habitat of Chinese caterpillar fungus would expand, with 0.11-4.87% expansion over current suitable habitat. Depending upon the representative concentration pathways, we observed both increase and decrease in average elevation of the suitable habitat range of the species.

  9. A review of therapeutic potential ofAjuga bracteosa:A critically endangered plant from Himalaya

    Institute of Scientific and Technical Information of China (English)

    Mubashir Hussain; Yamin Bibi; Naveed Iqbal Raja; Muhammad Iqbal; Sumaira Aslam; Nida Tahir; Muhammad Imran; Anam Iftikhar

    2016-01-01

    Medicinal plants are the nature’s gift for the humanity to treat various ailments and to spend a prosperous healthy life. There are almost 300 species ofAjuga. Among them,Ajuga bracteosa Wall. ex Benth (A. bracteosa) is an important medicinal plant of Himalaya regions. Its medicinal potential is due to the presence of various pharmacologically active compounds such as neo-clerodane diterpenoids, flavonol glycosides, iridoid glycosides, ergosterol-5,8-endoperoxide and phytoecdysones. The aim of this review article was to gather information aboutA. bracteosa which is currently scattered in form of various publications. This review article tried to attract the attention from people for therapeutic potential ofA. bracteosa. The present review comprises upto date information of botanical aspects, active ingredients, traditional uses, and pharmacological activities such as antitumor, antimicrobial, antimalarial, anti-inflammatory, cardiotonic activity, antiarthritic activity, antioxidant activity andin vitro production of secondary metabolites for pharmaceuticals. Due to remarkable medicinal potential and commercialization, this species is indexed into critically endangered category and it is facing extremely high risk of extinction. Conservation practices and management techniques should be carried out to protect this important species from extinction. Recent biotechnological approaches will be quite helpful for its conservation.

  10. Forest structure, diversity and regeneration potential along altitudinal gradient in Dhanaulti of Garhwal Himalaya

    Energy Technology Data Exchange (ETDEWEB)

    Saha, S.; Rajwar, G.S.; Kumar, M.

    2016-07-01

    Aim of the study: The aim of the present study was to understatnd the forest composition, structure, diversity and regeneration potential along altitudinal gradient. Area of study: The study was carried out in Dhanaulti forest which falls under temperate region of Garhwal Himalaya in Uttarakhand state, India. Material and Methods: Vegetation analysis was carried out using 10 quadrats at each altitude using a quadrate size of 10×10 m2. In each quadrate, categories of trees >30 cm cbh were considered as trees, 10-30cm cbh as saplings and <10 cm cbh as seedlings. The data were quantitatively analyzed. Main results: In upper and middle altitudes, Cedrus deodara was reported dominant tree whereas, in lower altitude Quercus leucotrichophora was reported dominant. Tree density was highest in lower altitude which reduced middle and upper altitudes whereas, total basal cover increased with increasing altitude. The increasing total basal cover with altitude could be because of the presence of Cedrus deodara trees having higher girth classes. In tree, sapling and seedling layers, diversity (H) and equitabiltiy (EC) decreased with increasing altitude. However, concentrations of dominace (CD) and beta diversity (BD have shown reverse trend with H and EC which increased with increasing altitudes, in each layer of tree, sapling and seedling. The distribution pattern of most species in all layers of trees, saplings and seedlings was contagious. The regeneration potential of the species has shown that some of the species in the absence of tree layer are still regenerating particularly, Rhododendron arboreum, Benthamidia capitata, Neolitsea pallens etc. It indicates that most of the species are shifting upward as they are getting suitable conditions. Research highlights: Altitude influence species composition, diversity and regeneration potential of species. (Author)

  11. Climate change in the Himalayas : current state of knowledge

    OpenAIRE

    Gautam, Mahesh R.; Timilsina, Govinda R.; Acharya, Kumud

    2013-01-01

    This paper reviews the literature on the potential biophysical and economic impacts of climate change in the Himalayas. Existing observations indicate that the temperature is rising at a higher rate in Nepal and Chinese regions of the Himalayas compared with rest of the Himalayas. A declining trend of monsoon in the western Indian Himalayas and an increasing trend in the eastern Indian Himalayas have been observed, whereas increasing precipitation and stream flow in many parts of Tibetan Plat...

  12. Antioxidant Potential and DNA Damage Protection by the Slate Grey Saddle Mushroom, Helvella lacunosa (Ascomycetes), from Kashmir Himalaya (India).

    Science.gov (United States)

    Shameem, Nowsheen; Kamili, Azra N; Ahmad, Mushtaq; Masoodi, F A; Parray, Javid A

    2016-01-01

    This study pertains to the radical scavenging potential of and DNA protection by Helvella lacunosa, an edible mushroom from Kashmir Himalaya (India). Different solvents, on the basis of their polarities, were used to extract all solvent-soluble bioactive compounds. Seven different antioxidant methods were also used to determine extensive radical scavenging activity. The mushroom ethanol extract and butanol extract showed effective scavenging activity of radicals at 95% and 89%, respectively. At 800 µg/mg, the ethanol extract was potent enough to protect DNA from degradation by hydroxyl radicals. It is evident from these findings that the presence of antioxidant substances signifies the use of H. lacunosa as food in the mountainous valleys of the Himalayan region.

  13. Stand Structure, Productivity and Carbon Sequestration Potential of Oak Dominated Forests in Kumaun Himalaya

    Directory of Open Access Journals (Sweden)

    Bijendra Lal

    2016-08-01

    Full Text Available Present study deals with stand structure, biomass, productivity and carbon sequestration in oak dominated forests mixed with other broad leaved tree species. The sites of studied forests were located in Nainital region between 29058’ N lat. and 79028’ E long at 1500-2150 m elevation. Tree density of forests ranged from 980-1100 ind.ha-1. Of this, oak trees shared 69-97%. The basal area of trees was 31.81 to 63.93 m2 ha-1. R. arboreum and Q. floribunda shared maximum basal area 16.45 and 16.32 m2 ha-1, respectively in forest site-1 and 2 while Quercus leucotrichophora shared maximum (35.69 m2 ha-1 in site-3. The biomass and primary productivity of tree species ranged from 481-569 t ha-1 and 16.9-20.9 t ha-1yr-1, respectively. Of this, biomass and primary productivity of oak tree species accounted for 81 to 95 and 78 to 98%, respectively. Carbon stock and carbon sequestration ranged from 228 to 270 t ha-1 and 8.0 to 9.9 t ha-1yr-1, respectively. The share of oak tree species ranged from 81 to 94.7 and 79 to 97%, respectively. The diversity of tree species ranged from 0.03 to 0.16 in forest sites-1, 2 and 3. The diversity of oak species was 0.08-0.16 in all the forest sites. Thus it is concluded that among the oak tree species, Quercus floribunda and Quercus leucotrichophora were highly dominated in the studied forests. The climax form of oak dominated trees in the studied forest sites depicted slightly lower richness and diversity of tree species compared to the forests in the region and elsewhere. As far as dry matter and carbon of forests is concerned, these estimates are close to the earlier reports of forests in the region. Therefore, studied forests have the potential to increase the diversity, productivity and carbon sequestration of forest tree species by providing the adequate scientific conservation and management inputs.

  14. Declining Large-Cardamom Production Systems in the Sikkim Himalayas: Climate Change Impacts, Agroeconomic Potential, and Revival Strategies

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    Ghanashyam Sharma

    2016-08-01

    Full Text Available Large cardamom (Amomum subulatum is an economically valuable, ecologically adaptive, and agro-climatically suitable perennial cash crop grown under tree shade in the eastern Himalayas. In Sikkim, India, the focus of this study, large-cardamom production peaked early in the 21st century, making India the largest producer in the world, but dropped sharply after 2004; Nepal is now the largest producer. This crop is an important part of the local economy, contributing on average 29.2% of the income of households participating in this study. Farmers and extension agencies have worked to reverse its decline since 2007, and thus, there is a steady increase in production and production area. After reviewing the literature, we carried out extensive field research in 6 locations in Sikkim in 2011–2013 to investigate the causes of this decline and measures being undertaken to reverse it, using a combination of rapid rural appraisal, participatory rural appraisal, structured questionnaire, and field sampling techniques. Study participants attributed the decline in large-cardamom farming to 4 broad types of drivers: biological, socioeconomic, institutional/governance-related, and environmental/climate-change-related. Altered seasons, erratic or scanty rainfall, prolonged dry spells, temperature increase, soil moisture loss, and increasing instances of diseases and pests were prominent factors of climate change in the study region. Multistakeholder analysis revealed that development and implementation of people-centered policy that duly recognizes local knowledge, development of disease-free planting materials, training, subsidies, and improved irrigation facilities are central to improving cardamom farming and building socioeconomic and ecological resilience.

  15. Evolution and variability of the Asian monsoon and its potential linkage with uplift of the Himalaya and Tibetan Plateau

    Science.gov (United States)

    Tada, Ryuji; Zheng, Hongbo; Clift, Peter D.

    2016-12-01

    Uplift of the Himalaya and Tibetan Plateau (HTP) and its linkage with the evolution of the Asian monsoon has been regarded as a typical example of a tectonic-climate linkage. Although this linkage remains unproven because of insufficient data, our understanding has greatly advanced in the past decade. It is thus timely to summarize our knowledge of the uplift history of the HTP, the results of relevant climate simulations, and spatiotemporal changes in the Indian and East Asian monsoons since the late Eocene. Three major pulses of the HTP uplift have become evident: (1) uplift of the southern and central Tibetan Plateau (TP) at ca. 40-35 Ma, (2) uplift of the northern TP at ca. 25-20 Ma, and (3) uplift of the northeastern to eastern TP at ca. 15-10 Ma. Modeling predictions suggest that (i) uplift of the southern and central TP should have intensified the Indian summer monsoon (ISM) and the Somali Jet at 40-35 Ma; (ii) uplift of the northern TP should have intensified the East Asian summer monsoon (EASM) and East Asian winter monsoon (EAWM), as well as the desertification of inland Asia at 25-20 Ma; and (iii) uplift of the northeastern and eastern TP should have further intensified the EASM and EAWM at 15-10 Ma. We tested these predictions by comparing them with paleoclimate data for the time intervals of interest. There are insufficient paleoclimate data to test whether the ISM and Somali Jet intensified with the uplift of the southern and central TP at 40-35 Ma, but it is possible that such uplift enhanced erosion and weathering that drew down atmospheric CO2 and resulted in global cooling. There is good evidence that the EASM and EAWM intensified, and desertification started in inland Asia at 25-20 Ma in association with the uplift of the northern TP. The impact of the uplift of the northeastern and eastern TP on the Asian monsoon at 15-10 Ma is difficult to evaluate because that interval was also a time of global cooling and Antarctic glaciation that might also

  16. Potential theory—selected topics

    CERN Document Server

    Aikawwa, Hiroaki

    1996-01-01

    The first part of these lecture notes is an introduction to potential theory to prepare the reader for later parts, which can be used as the basis for a series of advanced lectures/seminars on potential theory/harmonic analysis. Topics covered in the book include minimal thinness, quasiadditivity of capacity, applications of singular integrals to potential theory, L(p)-capacity theory, fine limits of the Nagel-Stein boundary limit theorem and integrability of superharmonic functions. The notes are written for an audience familiar with the theory of integration, distributions and basic functional analysis.

  17. Detection of snow melt and freezing in Himalaya using OSCAT data

    Indian Academy of Sciences (India)

    Rajashree V Bothale; P V N Rao; C B S Dutt; V K Dadhwal

    2015-02-01

    A study of the snow cover melt and freeze using Ku band Oceansat scatterometer (OSCAT) HH polarised backscatter coefficient (0HH) for 2011 and 2012 is reported for the Himalayas, which contain the world’s largest reserve of ice and snow outside polar regions. The analysis shows spatial and temporal inter-annual variations in the onset of melt/freeze across four regions (Upper Himalaya, Western Himalaya, Central Himalaya, and Eastern Himalaya), nine elevation bands and four aspect zones. A threshold based on temperature–0HH relation and average 0HH for the months January–March was used for melt/freeze detection. When the three consecutive images (6 days) satisfied the threshold, the day of first image was selected as melt onset/freeze day. The average melt onset dates were found to be March 11 ± 11 days for Eastern Himalaya, April 3 ± 18 days for Central Himalaya, April 16 ± 27 days for Western Himalaya, and May 12 ± 18 days for Upper Himalaya. Similarly average freeze onset dates were found to be August 23 ± 27 days for Eastern Himalaya, September 08 ± 24 days for Central Himalaya, August 27 ± 11 days for Western Himalaya, and September 13 ± 11 days for Upper Himalaya. All the zones experienced the melt onset earlier by around 20 days in 2011 at elevation above 5000 m. All the zones experienced freeze earlier in 2012, with onset being 18, 19, 11, and 21 days earlier in Eastern, Central, Western, and Upper Himalaya, respectively.

  18. Himalaya evolution at Paleogene-Neogene boundary unraveled by zircon age spectrum from Arabian Sea Sediments

    Science.gov (United States)

    Feng, Han; Lu, Huayu; Zhang, Hanzhi

    2016-04-01

    Although virtually all the intensive orogenic activities of Himalaya occurred in Neogene, the tectonic evolution of this high mountain range in Paleogene is poorly understood. Investigations of tectonic change pattern at Paleogene-Neogene boundary are important to better understand the interaction between mountain building and climate evolution. Here we present new U-Pb ages of zircon grains from Indus Fan sediments to constrain the orogenic history of Himalaya at Paleogene-Neogene boundary. 11 samples between late Oligocene and early Miocene from ODP 117 cores are dated by the zircon U-Pb technique. We calculate relative contributions of potential sources by counting zircon grains for each sample, and the quantized results indicate Himalaya contributed sediments to the coring site, and an extremely high input from Great and Tethyan Himalaya during late Oligocene-early Miocene. Four samples in Pleistocene are also dated for comparison, which indicates that high proportion of Lesser Himalaya has contributed to the sediment in Pleistocene. Our results suggest that the high contribution of Great and Tethyan Himalaya at Paleogene-Neogene boundary might correlate with the beginning of activity of MCT and extension of STD with leucogranite intrusion along Himalaya, which give rise to the extensive Great Himalaya exhumation. Our study demonstrates that zircon U-Pb dating technique is a good tool to reconstruct erosional history of mountain building on a tectonic timescale. Key words: ODP, Himalaya, Indus Fan, zircon U-Pb dating, Paleogene-Neogene boundary

  19. Antioxidant, Hepatoprotective Potential and Chemical Profiling of Propolis Ethanolic Extract from Kashmir Himalaya Region Using UHPLC-DAD-QToF-MS

    Science.gov (United States)

    Wali, Adil F.; Avula, Bharathi; Ali, Zulfiqar; Khan, Ikhlas A.; Mushtaq, Ahlam; Rehman, Muneeb U.; Akbar, Seema; Masoodi, Mubashir Hussain

    2015-01-01

    The aim of this study was to examine hepatoprotective effect of ethanolic extract of propolis (KPEt) from Kashmir Himalaya against isoniazid and rifampicin (INH-RIF) induced liver damage in rats. Hepatic cellular injury was initiated by administration of INH-RIF combination (100 mg/kg) intraperitoneal (i.p.) injection for 14 days. We report the protective effects of KPEt against INH-RIF induced liver oxidative stress, inflammation, and enzymatic and nonenzymatic antioxidants. Oral administration of KPEt at both doses (200 and 400 mg/kg body weight) distinctly restricted all modulating oxidative liver injury markers and resulted in the attenuation of INH-RIF arbitrated damage. The free radical scavenging activity of KPEt was evaluated by DPPH, nitric oxide, and superoxide radical scavenging assay. The components present in KPEt identified by ultra high performance liquid chromatography diode array detector time of flight-mass spectroscopy (UHPLC-DAD-QToF-MS) were found to be flavonoids and phenolic acids. The protective efficacy of KPEt is possibly because of free radical scavenging and antioxidant property resulting from the presence of flavonoids and phenolic acids. PMID:26539487

  20. Antioxidant potential of selected Spirulina platensis preparations.

    Science.gov (United States)

    Dartsch, Peter C

    2008-05-01

    Recent studies suggest that Spirulina, a unicellular blue-green alga, may have a variety of health benefits and therapeutic properties and is also capable of acting as an antioxidant and antiinflammatory agent. In this study, a cell-free and a cell-based test assay were used to examine the antioxidant and antiinflammatory properties of four selected Spirulina platensis preparations: (1) Biospirulina, (2) SpiruComplex, a preparation with naturally bound selenium, chromium and zinc, (3) SpiruZink, a preparation with naturally bound zinc, (4) Zinkspirulina + Acerola, a preparation with naturally bound zinc and acerola powder. The cell-free test assay used potassium superoxide as a donor for superoxide radicals, whereas the cell-based test assay used the formation of intracellular superoxide radicals of functional neutrophils upon stimulation by phorbol-12-myristate-13-acetate as a model to investigate the potential of Spirulina preparations to inactivate superoxide radicals. In accordance with the recommended daily dosage, test concentrations ranging from 50 to 1000 microg/mL were chosen. The results showed a dose-dependent inactivation of free superoxide radicals (antioxidant effect) as well as an antiinflammatory effect characterized by a dose-dependent reduction of the metabolic activity of functional neutrophils and a dose-dependent inactivation of superoxide radicals generated during an oxidative burst. The results demonstrate that the tested Spirulina preparations have a high antioxidant and antiinflammatory potential. Especially SpiruZink and Zinkspirulina + Acerola might be useful as a supportive therapeutic approach for reducing oxidative stress and/or the generation of oxygen radicals in the course of inflammatory processes.

  1. Glacial lakes in the Indian Himalayas--from an area-wide glacial lake inventory to on-site and modeling based risk assessment of critical glacial lakes.

    Science.gov (United States)

    Worni, Raphael; Huggel, Christian; Stoffel, Markus

    2013-12-01

    Glacial lake hazards and glacial lake distributions are investigated in many glaciated regions of the world, but comparably little attention has been given to these topics in the Indian Himalayas. In this study we present a first area-wide glacial lake inventory, including a qualitative classification at 251 glacial lakes >0.01 km(2). Lakes were detected in the five states spanning the Indian Himalayas, and lake distribution pattern and lake characteristics were found to differ significantly between regions. Three glacial lakes, from different geographic and climatic regions within the Indian Himalayas were then selected for a detailed risk assessment. Lake outburst probability, potential outburst magnitudes and associated damage were evaluated on the basis of high-resolution satellite imagery, field assessments and through the use of a dynamic model. The glacial lakes analyzed in the states of Jammu and Kashmir and Himachal Pradesh were found to present moderate risks to downstream villages, whereas the lake in Sikkim severely threatens downstream locations. At the study site in Sikkim, a dam breach could trigger drainage of ca. 16×10(6)m(3) water and generate maximum lake discharge of nearly 7000 m(3) s(-). The identification of critical glacial lakes in the Indian Himalayas and the detailed risk assessments at three specific sites allow prioritizing further investigations and help in the definition of risk reduction actions.

  2. Ectomycorrhizal diversity associated with Cedrus deodara and Pinus wallichiana in the Kashmir Himalaya, India.

    Science.gov (United States)

    Itoo, Zahoor Ahmad; Reshi, Zafar A

    2014-01-01

    The present study was undertaken to document the ectomycorrhizal diversity associated with the Cedrus deodara and Pinus wallichiana in the Kashmir Himalaya, India. The extensive field surveys carried out in the Kashmir Himalaya at five study sites resulted in the collection and identification of 76 potential ectomycorrhizal fungal species associated with the Cedrus deodara and Pinus wallichiana. Maximum 32 number of species were found associated with Pinus wallichiana, 19 with Cedrus deodara and 25 species were found growing in association with both the conifers. The present study reveals that Cedrus deodara and Pinus wallichiana in the Kashmir Himalaya, India harbour diverse ectomycorrhizal fungal species.

  3. Transboundary Air Pollution over the Central Himalayas: Monitoring network and Preliminary Results

    Science.gov (United States)

    Zhang, Qianggong; Kang, Shichang

    2016-04-01

    The Himalayas, stretching over 3000 kms along west-east, separates South Asia continent and the Tibetan Plateau with its extreme high altitudes. The South Asia is being increasingly recognized to be among the hotspots of air pollution, posing multi-effects on regional climate and environment. Recent monitoring and projection have indicated an accelerated decrease of glacier and increasing glacier runoff in the Himalayas, and a remarkable phenomenon has been recognized in the Himalayas that long-range transport atmospheric pollutants (e.g., black carbon and dust) deposited on glacier surface can promote glacier melt, and in turns, may liberate historical contaminant legacy in glaciers into downward ecosystems. To understand the air pollution variation and how they can infiltrate the Himalayas and beyond, we started to operate a coordinated atmospheric pollution monitoring network composing 11 sites with 5 in Nepal and 6 in Tibet since April 2013. Atmospheric total suspended particles ( TSP air mass trajectories suggested that the transboundary air pollution over the Himalayas is episodic and is likely concentrated in pre-monsoon seasons. Our results emphasis the potential transport and impact of air pollution from South Asia to Himalayas and further inland Tibetan Plateau. The monitoring network will be continuously operated to provide basis for defining the transboundary air pollution and their impact on the environments and ecosystems over the Himalayas and the Tibetan Plateau.

  4. Copycats of the Central Himalayas

    NARCIS (Netherlands)

    P.A. Arora (Payal)

    2009-01-01

    textabstractThis case study highlights practices of a rarely documented group of neo-users of the Internet or newbies from Central Himalayas, serving as a catalyst for delving deeply into the act of ‘plagiarism’ in online learning By looking at such ‘learning’ practices away from schools, namely at

  5. Ethnobotany in the Nepal Himalaya

    Directory of Open Access Journals (Sweden)

    Bussmann Rainer W

    2008-12-01

    Full Text Available Abstract Background Indigenous knowledge has become recognized worldwide not only because of its intrinsic value but also because it has a potential instrumental value to science and conservation. In Nepal, the indigenous knowledge of useful and medicinal plants has roots in the remote past. Methods The present study reviews the indigenous knowledge and use of plant resources of the Nepal Himalayas along the altitudinal and longitudinal gradient. A total of 264 studies focusing on ethnobotany, ethnomedicine and diversity of medicinal and aromatic plants, carried out between 1979 and 2006 were consulted for the present analysis. In order to cross check and verify the data, seven districts of west Nepal were visited in four field campaigns. Results In contrast to an average of 21–28% ethnobotanically/ethnomedicinally important plants reported for Nepal, the present study found that up to about 55% of the flora of the study region had medicinal value. This indicates a vast amount of undocumented knowledge about important plant species that needs to be explored and documented. The richness of medicinal plants decreased with increasing altitude but the percentage of plants used as medicine steadily increased with increasing altitude. This was due to preferences given to herbal remedies in high altitude areas and a combination of having no alternative choices, poverty and trust in the effectiveness of folklore herbal remedies. Conclusion Indigenous knowledge systems are culturally valued and scientifically important. Strengthening the wise use and conservation of indigenous knowledge of useful plants may benefit and improve the living standard of poor people.

  6. Estimating the potential for in-line hydropower in the Himalayas: from global remote sensing data to local flow duration curves

    Science.gov (United States)

    Muller, M. F.; Thompson, S. E.; Hermanowicz, S. W.; Jordan, F.

    2012-12-01

    Adopting multi-use systems in rural water infrastructure is a promising strategy to improve the sustainability of water utilities. For example, in-line hydropower - an infrastructure concept that combines water supply and micro-hydropower - has been successfully implemented in Switzerland for a century. Net profit from electricity is used to cross-subsidize water supply, improving the financial sustainability of water utilities. The concept is transferable to mountainous regions of developing countries, where it promises to alleviate the financial constraints that currently inhibit water supply development. Yet field attempts are missing to evaluate the success of trial in-line hydropower implementations, and a dearth of distributed hydrological and meteorological data complicates evaluations of the potential for future development. In this context, remote sensing offers a powerful technique to overcome data-scarcity issues in developing nations to facilitate the development of appropriate water supply technology. To utilize remotely sensed data for infrastructure planning, however, downscaling and regionalization challenges have to be addressed, especially in the mountainous regions where in-line hydropower would be applicable. Nepal offers an excellent test-bed to explore the potential for incorporating remote-sensing data into water resources planning. Here we present initial downscaling of TRMM daily precipitation data to a 5 x 5 km grid, including bias correction and explicit consideration of elevation effects. Several complementary approaches, including fractal downscaling, statistical downscaling and CDF-matching bias correction are evaluated through a cross-validation process. The results are used to drive different regionalization approaches for flow duration curves of Nepalese rivers. Finally, the relevance of in-line hydropower in rural mountainous communities is briefly discussed, based on feasibility assessments recently conducted in Central Nepal.

  7. Potential probiotic attributes and antagonistic activity of an indigenous isolate Lactobacillus plantarum DM5 from an ethnic fermented beverage "Marcha" of north eastern Himalayas.

    Science.gov (United States)

    Das, Deeplina; Goyal, Arun

    2014-05-01

    A novel isolate DM5 identified as Lactobacillus plantarum displayed in vitro probiotic properties as well as antimicrobial activity. It showed adequate level of survival to the harsh conditions of the gastrointestinal tract and survived low acidic pH 2.5 for 5 h. Artificial gastric juice and intestinal fluidic environment decreased the initial viable cell population of isolate DM5 only by 7% and 13%, respectively, while lysozyme (200 µg/ml) and bile salt (0.5%) enhanced its growth. It was found to deconjugate taurodeoxycholic acid, indicating its potential to reduce hypercholesterolemia. Isolate DM5 demonstrated cell surface hydrophobicity of 53% and autoaggregation of 54% which are the prerequisite for adhesion to epithelial cells and colonization to host. Bacteriocin activity of isolate was found to be 6400 AU/ml as it inhibited the growth of food borne pathogens Escherichia coli, Staphylococcus aureus, and Alcaligenes faecalis. The bactericidal action of bacteriocin from isolate was analyzed by flow cytometry, rendering its use as prospective probiotic and starter culture in food industry.

  8. A Cryosphere Monitoring Project in the Himalayas

    Science.gov (United States)

    Stumm, D.; Mool, P. K.; Shresta, A. B.; Joshi, S. P.; Bajracharya, S. R.; Kayastha, R. B.; Devkota, L. P.; Bajracharya, O. R.

    2011-12-01

    The Cryosphere Monitoring Project (CMP) has been initiated by ICIMOD (International Centre for Integrated Mountain Development) with the aim to gain more knowledge about the cryosphere in the Himalayas and to build capacities in Nepalese organisations. The CMP is carried out in collaboration with the Kathmandu University, Tribhuvan University, the Department of Hydrology and Meteorology and the Water and Energy Commission Secretariat, and is sponsored by the Royal Norwegian Embassy. The CMP has a multilevel and integrative approach and consists of the following five components: (1) glacier monitoring, (2) assessment of current and future water resources at catchment and sub-basin scale, (3) multi-level remote sensing based observations for glacier and snow monitoring, (4) strengthening ICIMOD as regional knowledge hub for cryospheric information, (5) capacity building of Nepalese organisations. The glacier monitoring component includes field-based mass balance, geometry and glacier flow measurements on two clean and one debris-covered glacier and their analysis, as well as snow cover measurements. The in-situ glacier measurements promote process understanding, provide a refined temporal resolution of mass balance data and data for calibration of glacio-hydrological models. To assess current water resources, meteorological and hydrological measurements are initiated and the run-off is calculated with glacio-hydrological and snow-melt models for the catchments of the selected glaciers. Future water availability will be assessed by down-scaling regional climate model (RCM) data that is applied to the glacio-hydrological model. Remote sensing data is used to improve spatial information about the glacier distribution by refining glacier inventories, and to calculate the geodetic mass balance for the selected glaciers to complement the directly measured glacier mass balance. Additionally, the operation of a MODIS satellite receiving station is planned to obtain near real

  9. Changes in Rongbuk lake and Imja lake in the Everest region of Himalaya

    Science.gov (United States)

    Chen, W.; Doko, T.; Liu, C.; Ichinose, T.; Fukui, H.; Feng, Q.; Gou, P.

    2014-12-01

    The Himalaya holds the world record in terms of range and elevation. It is one of the most extensively glacierized regions in the world except the Polar Regions. The Himalaya is a region sensitive to climate change. Changes in the glacial regime are indicators of global climate changes. Since the second half of the last century, most Himalayan glaciers have melted due to climate change. These changes directly affected the changes of glacial lakes in the Himalayan region due to the glacier retreat. New glacial lakes are formed, and a number of them have expanded in the Everest region of the Himalayas. This paper focuses on the two glacial lakes which are Imja Lake, located at the southern slope, and Rongbuk Lake, located at the northern slope in the Mt. Everest region, Himalaya to present the spatio-temporal changes from 1976 to 2008. Topographical conditions between two lakes were different (Kruskal-Wallis test, p Lake was located at 623 m higher than Imja Lake, and radiation of Rongbuk Lake was higher than the Imja Lake. Although size of Imja Lake was larger than the Rongbuk Lake in 2008, the growth speed of Rongbuk Lake was accelerating since 2000 and exceeds Imja Lake in 2000-2008. This trend of expansion of Rongbuk Lake is anticipated to be continued in the 21st century. Rongbuk Lake would be the biggest potential risk of glacial lake outburst flood (GLOF) at the Everest region of Himalaya in the future.

  10. The duct selective volumetric receiver: potential for different selectivity strategies and stability issues

    Energy Technology Data Exchange (ETDEWEB)

    Garcia-Casals, X. [Universidad Pontificia Comillas-ICAI, Madrid (Spain). Dept. de Fluidos y Calor; Ajona, J.I. [Departamento de Energia Solar, Viessemann, Poligono Industrial San Marcos, Getafe (Spain)

    1999-07-01

    Recently much theoretical and experimental work has been conducted on volumetric receivers. However, not much attention has been paid to the possibilities of using different selectivity mechanisms to minimize radiation thermal losses, which are the main ones at high operating temperature. In this paper we present a duct volumetric receiver model and its results, which allow the evaluation of different selectivity strategies such as: conventional {epsilon}/{alpha}, geometry, frontal absorption and diffuse/specular reflection. We propose a new concept of selective volumetric receivers based on a solar-specular/infrared-diffuse radiative behaviour and evaluate its potential for efficiency improvement. In recent work on volumetric receivers based on simplified models, it has been concluded that the duct volumetric receiver is inherently unstable when working with high solar flux. We didn't find any unstable receiver behaviour even at very high solar fluxes, and conclude that a substantial potential for efficiency improvement exists if selectivity mechanisms are properly combined. (author)

  11. Resource efficiency potential of selected technologies, products and strategies.

    Science.gov (United States)

    Rohn, Holger; Pastewski, Nico; Lettenmeier, Michael; Wiesen, Klaus; Bienge, Katrin

    2014-03-01

    Despite rising prices for natural resources during the past 30 years, global consumption of natural resources is still growing. This leads to ecological, economical and social problems. So far, however, limited effort has been made to decrease the natural resource use of goods and services. While resource efficiency is already on the political agenda (EU and national resource strategies), there are still substantial knowledge gaps on the effectiveness of resource efficiency improvement strategies in different fields. In this context and within the project "Material Efficiency and Resource Conservation", the natural resource use of 22 technologies, products and strategies was calculated and their resource efficiency potential analysed. In a preliminary literature- and expert-based identification process, over 250 technologies, strategies, and products, which are regarded as resource efficient, were identified. Out of these, 22 subjects with high resource efficiency potential were selected. They cover a wide range of relevant technologies, products and strategies, such as energy supply and storage, Green IT, transportation, foodstuffs, agricultural engineering, design strategies, lightweight construction, as well as the concept "Using Instead of Owning". To assess the life-cycle-wide resource use of the selected subjects, the material footprint has been applied as a reliable indicator. In addition, sustainability criteria on a qualitative basis were considered. The results presented in this paper show significant resource efficiency potential for many technologies, products and strategies.

  12. Brief Communication: Contending estimates of 2003-2008 glacier mass balance over the Pamir-Karakoram-Himalaya

    Science.gov (United States)

    Kääb, A.; Treichler, D.; Nuth, C.; Berthier, E.

    2015-03-01

    We present glacier thickness changes over the entire Pamir-Karakoram-Himalaya arc based on ICESat satellite altimetry data for 2003-2008. We highlight the importance of C-band penetration for studies based on the SRTM elevation model. This penetration seems to be of potentially larger magnitude and variability than previously assumed. The most negative rate of region-wide glacier elevation change (mass-gain anomaly rather than its centre. For the Ganges, Indus and Brahmaputra basins, the glacier mass change reaches -24 ± 2 Gt yr-1, about 10% of the current glacier contribution to sea-level rise. For selected catchments, we estimate glacier imbalance contributions to river run-off from a few percent to greater than 10%.

  13. Selective oestrogen receptor modulators differentially potentiate brain mitochondrial function.

    Science.gov (United States)

    Irwin, R W; Yao, J; To, J; Hamilton, R T; Cadenas, E; Brinton, R D

    2012-01-01

    The mitochondrial energy-transducing capacity of the brain is important for long-term neurological health and is influenced by endocrine hormone responsiveness. The present study aimed to determine the role of oestrogen receptor (ER) subtypes in regulating mitochondrial function using selective agonists for ERα (propylpyrazoletriol; PPT) and ERβ (diarylpropionitrile; DPN). Ovariectomised female rats were treated with 17β-oestradiol (E(2) ), PPT, DPN or vehicle control. Both ER selective agonists significantly increased the mitochondrial respiratory control ratio and cytochrome oxidase (COX) activity relative to vehicle. Western blots of purified whole brain mitochondria detected ERα and, to a greater extent, ERβ localisation. Pre-treatment with DPN, an ERβ agonist, significantly increased ERβ association with mitochondria. In the hippocampus, DPN activated mitochondrial DNA-encoded COX I expression, whereas PPT was ineffective, indicating that mechanistically ERβ, and not ERα, activated mitochondrial transcriptional machinery. Both selective ER agonists increased protein expression of nuclear DNA-encoded COX IV, suggesting that activation of ERβ or ERα is sufficient. Selective ER agonists up-regulated a panel of bioenergetic enzymes and antioxidant defence proteins. Up-regulated proteins included pyruvate dehydrogenase, ATP synthase, manganese superoxide dismutase and peroxiredoxin V. In vitro, whole cell metabolism was assessed in live primary cultured hippocampal neurones and mixed glia. The results of analyses conducted in vitro were consistent with data obtained in vivo. Furthermore, lipid peroxides, accumulated as a result of hormone deprivation, were significantly reduced by E(2) , PPT and DPN. These findings suggest that the activation of both ERα and ERβ is differentially required to potentiate mitochondrial function in brain. As active components in hormone therapy, synthetically designed oestrogens as well as natural phyto-oestrogen cocktails

  14. Glacier Changes in the Bhutanese Himalaya - Present and Future

    Science.gov (United States)

    Rupper, S.; Schaefer, J. M.; Burgener, L. K.; Maurer, J.; Smith, R.; Cook, E.; Putnam, A. E.; Krusic, P.; Tsering, K.; Koenig, L.

    2012-12-01

    Glacierized change in the Himalayas affects river-discharge, hydro-energy and agricultural production, and Glacial Lake Outburst Flood potential, but its quantification and extent of impacts remains highly uncertain. Here we present conservative, comprehensive and quantitative predictions for glacier area and meltwater flux changes in Bhutan, monsoonal Himalayas. In particular, we quantify the uncertainties associated with the glacier area and meltwater flux changes due to uncertainty in climate data, a critical problem for much of High Asia. Based on a suite of gridded climate data and a robust glacier melt model, our results show that glacier area and meltwater change projections can vary by an order of magnitude for different climate datasets. The most conservative results indicate that, even if climate were to remain at the present-day mean values (1980-2000), almost 10% of Bhutan's glacierized area would vanish and the meltwater flux would drop by as much as 30%. New mapping of glacierized area from 2000-2010 shows a significant change in glacierized area of 4-6%. Thus the conservative steady-state area changes predicted by the model are already being realized. Under the conservative scenario of an additional 1°C regional warming, glacier retreat is predicted to continue until about 25% of Bhutan's glacierized area will have disappeared and the annual meltwater flux, after an initial spike, would drop by as much as 65%.

  15. Bitropic D3 Dopamine Receptor Selective Compounds as Potential Antipsychotics.

    Science.gov (United States)

    Luedtke, Robert R; Rangel-Barajas, Claudia; Malik, Mahinder; Reichert, David E; Mach, R H

    2015-01-01

    modified to develop bivalent ligands capable of interacting with receptor dimers or oligomers are also provided. Preclinical studies using bitropic D3 dopamine receptor selective ligands are also discussed as strategy to pharmacologically dissect the role of the D2 and D3 dopamine receptor subtypes in animal models of neuropsychiatric, neurological and substance abuse disorders. This research has the potential to a) advance the understanding of the role of the D2 and D3 dopamine receptor subtypes in neuropsychiatric disorders and b) lead to new treatment strategies for neuropsychiatric disorders.

  16. Visual evoked potentials and selective attention to points in space

    Science.gov (United States)

    Van Voorhis, S.; Hillyard, S. A.

    1977-01-01

    Visual evoked potentials (VEPs) were recorded to sequences of flashes delivered to the right and left visual fields while subjects responded promptly to designated stimuli in one field at a time (focused attention), in both fields at once (divided attention), or to neither field (passive). Three stimulus schedules were used: the first was a replication of a previous study (Eason, Harter, and White, 1969) where left- and right-field flashes were delivered quasi-independently, while in the other two the flashes were delivered to the two fields in random order (Bernoulli sequence). VEPs to attended-field stimuli were enhanced at both occipital (O2) and central (Cz) recording sites under all stimulus sequences, but different components were affected at the two scalp sites. It was suggested that the VEP at O2 may reflect modality-specific processing events, while the response at Cz, like its auditory homologue, may index more general aspects of selective attention.

  17. The role of glaciers in stream flow from the Nepal Himalaya

    Science.gov (United States)

    Alford, D.; Armstrong, R.

    2010-04-01

    Recent concerns related to the potential impacts of the retreat of Himalayan glaciers on the hydrology of rivers originating in the catchment basins of the Himalaya have been accompanied by few analyses describing the role of glaciers in the hydrologic regime of these mountains. This is, at least in part, a result of the relative inaccessibility of the glaciers of the Himalaya, at altitudes generally between 4000-7000 m, and the extreme logistical difficulties of: 1) reaching the glaciers, and 2) conducting meaningful research once they have been reached. It is apparent that an alternative to traditional "Alpine" glaciology is required in the mountains of the Hindu Kush-Himalaya region. The objectives of the study discussed here have been to develop methodologies that will begin to quantify the role of complete glacier systems in the hydrologic regime of the Nepal Himalaya, and to develop estimates of the potential impact of a continued retreat of these glacier, based on the use of disaggregated low-altitude data bases, topography derived from satellite imagery, and simple process models of water and energy exchange in mountain regions. While the extent of mesoscale variability has not been established by studies to date, it is clear that the dominant control on the hydrologic regime of the tributaries to the Ganges Basin from the eastern Himalaya is the interaction between the summer monsoon and the 8000 m of topographic relief represented by the Himalayan wall. All the available evidence indicates that the gradient of specific runoff with altitude resulting from this interaction is moderately to strongly curvilinear, with maximum runoff occurring at mid-altitudes, and minima at the altitudinal extremes. At the upper minimum of this gradient, Himalayan glaciers exist in what has been characterized as an "arctic desert". The methodologies developed for this study involve the relationship between area-altitude distributions of catchment basins and glaciers, based on

  18. Rock magnetic survey of Himalaya-Karakoram ranges, northern Pakistan; Pakistan hokubu, Himalaya-Karakoram tai no ganseki jikigakuteki chosa

    Energy Technology Data Exchange (ETDEWEB)

    Yoshida, M. [Geoscience Co. Ltd., Tokyo (Japan); Khadim, I.; Ahmad, M. [Geological Survey of Pakistan, Islamabad (Pakistan)

    1997-10-22

    This paper describes results of the rock magnetic survey mainly including measurement of magnetic susceptibility conducted in the northern Pakistan from 1992 to 1997. Magnetic characteristics in Himalaya-Karakoram ranges and prospective ore deposits are also described. Magnetic susceptibility data measured in this district were summarized as a frequency map in each geological block. Granitoids in the northern part of Kohistan batholith and granitoids of Ladakh batholith showed remarkably high magnetic susceptibility values, which suggested they are magnetite-series magmatism. It has been known that magnetite-series magmatism often accompanies sulfide-forming mineral resources, which suggests high potentiality of abundant mineral resources containing Mo, Cu, Pb, Zn, Ag and Au. From the results of the magnetic susceptibility measurements and the above-mentioned models, accordingly, it can be pointed out that the northern part of Kohistan batholith, the distribution area of Ladakh batholith, and surrounding areas are promising targets for mineral resources exploration in the Himalaya-Karakoram ranges, northern Pakistan. 5 refs., 3 figs.

  19. Selection of potential microorganism for sago starch fermentation

    Directory of Open Access Journals (Sweden)

    RUTH MELLIAWATI

    2006-02-01

    Full Text Available Fermentation process of sago starch for the production of bioproduct requires potential microorganism that have ability to hydrolyze sago starch. The purpose of this research was to get the potential of amylolytic microorganisms for their capability of amyloglucosidase activity and to know the sugar strains of the fermentation result. Eleven amylolytic microorganisms (9 strains of mold and 2 strains of yeast were obtained from the collection Research Centre for Biotechnology – Indonesian Institute of Sciences (LIPI, Cibinong-Bogor were used. The selection step was carried out based on their capability of starch hydrolysis to reducing sugar. The best result indicates that the production of reducing sugar reached the highest 18.485 ppm and amyloglucosidase activities was 3.583 units by KTU-1 strain. The highest total acid obtained was 5.85 mg/mL by Rhizopus IFO.R5442. The cell biomass was obtained between 0.5 to 1.74 g dry weight/100 mL and pH of the final fermentation (72 h were 3.57 to 8.38.

  20. Brain potentials during selective attention, memory search, and mental rotation.

    Science.gov (United States)

    Wijers, A A; Otten, L J; Feenstra, S; Mulder, G; Mulder, L J

    1989-07-01

    Event-related potentials were measured in a task that combined the classic selective attention paradigm with memory search and mental rotation paradigms. Subjects were required to attend to stimulus letters in one color and to ignore stimuli in a different color. Within the attended category subjects searched for target letters from a prememorized set (the memory set) and indicated whether they were presented normally or in mirror-image. Letters in all stimulus categories were presented randomly in either their upright position or rotated over 60 degrees, 120 degrees, or 180 degrees. The event-related potentials showed that the earliest effect of attending to color was a positivity at the anterior electrodes and a negativity at Oz (onset about 150 ms), followed by the enhancement of a central N2 component (N2b, onset about 220 ms). The early effect is thought to reflect selective processing of elementary stimulus features, the later N2b the covert orienting of attention. A later, prolonged central negativity elicited by attended stimuli covaried with the duration of the memory search process. Target detection resulted in a parietal P3b component, and also in an earlier negativity (in the range approximately 200-300 ms) to both attended and unattended targets, suggesting an early preattentive target classification. There were two effects of the rotation of stimuli. First there was an early occipital effect (about 200-300 ms), irrespective of attention and stimulus categories. It was argued that this effect reflected the preattentive identification of the orientation of the stimulus letters. A later (onset about 350-400 ms) parietal effect consisted of an increase in negativity as a function of the angle over which letters were rotated. This prolonged negativity had a later onset latency than the search-related negativity, and was restricted to the event-related potentials to target letters in the attended input channel. It was suggested that this component is the

  1. Flora of the Pan-Himalayas: General guidelines

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Editorial Committee,Flora of the Pan-Himalayas [May 2011]1.The Pan-Himalayas (the Himalayas and adjacent regions) forms a natural geographic unit,from the Wakhan Corridor and northeastern Hindu Kush eastwards to the Hengduan Mountains by way of Karakorum and the Himalayas.This region covers the northeastern corner of Afghanistan,northern Pakistan,northern India,Nepal,Bhutan,northern Myanmar,and southwest China (S Tibet,SE Qinghai,SE Gansu,W Sichuan,and NW Yunnan).

  2. CODA Q estimates for Kumaun Himalaya

    Indian Academy of Sciences (India)

    A Paul; S C Gupta; Charu C Pant

    2003-12-01

    Coda (c) estimates for the Kumaun Himalaya region have been obtained in high frequency range. Local earthquakes, recorded by a digital seismic network in the region, which fall in the epicentral distances range of 10 to 80km and with a local magnitude range of 1.4 to 2.8, have been used. The coda waves of 30 sec window length, filtered at seven frequency bands centered at 1.5, 3, 6, 9, 12, 18 and 24 Hz, have been analysed using the single backscattering model. The values of c estimates vary from 65 to 283 at 1.5 Hz to 2119 to 3279 at 24.0 Hz which showed that c is frequency dependent and its value increases as frequency increases. A frequency-dependent c relationship, c = (92 ± 4.73) (1.07 ± .023), is obtained for the region representing the average attenuation characteristics of seismic waves for Kumaun Himalaya region.

  3. 19th Himalaya-Karakoram-Tibet Workshop

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    The 19th Himalaya-Karakoram-Tibet Workshop (HKT19), as an annual international workshop devoted to presentations of new research findings in the Earth sciences and related disciplines from the Himalaya-Karakoram-Tibet (HKT) region and discussion on the burning issues, was held in Niseko, a famous ski resort in Hokkaido,Japan. The HKT19 Organizing Committee hosted the workshop together with two 21st Century Center of Excellence Programs,namely, COE for the “Neo-Science of Natural History” (Hokkaido University, Project Leader: H. Okada), COE for “Dynamics of the Sun-Earth-Life Interactive System”,(Nagoya University, Project Leader: T.Yasunari), and the Division of Earth and Planetary Sciences, Hokkaido University,

  4. Evolution of earthquake-triggered landslides in the Kashmir Himalaya, northern Pakistan

    Science.gov (United States)

    Khattak, G.A.; Owen, L.A.; Kamp, U.; Harp, E.L.

    2010-01-01

    The influence of the 08 October 2005 Kashmir earthquake and subsequent snow melt and monsoon rainfall on slope stability was evaluated using repeat photography in the Kashmir Himalaya of northern Pakistan. Sixty-eight landslide-affected locations were selected and photographed in November 2005, May/June 2006, June 2007, and August 2007 to evaluate all potential geomorphic changes. Eighty percent of the locations showed no or very little change, 11% of the locations showed a partial vegetation recovery on the slopes, while 9% showed an increase in the landslide area. All those locations that showed an increase in landsliding were located along rivers and/or roads. The small change in landslide extent is remarkable given that the region experienced one of the heaviest monsoon seasons in the last decade and is counter to earlier predictions of accelerated slope erosion by landsliding in the immediate years following the earthquake. Extensive fissures and ground cracks at many localities, however, still present a potential of future landsliding under wetter conditions. ?? 2009 Elsevier B.V. All rights reserved.

  5. Therapeutic potential of cannabinoids in neurodegenerative disorders: a selective review.

    Science.gov (United States)

    Velayudhan, Latha; Van Diepen, Erik; Marudkar, Mangesh; Hands, Oliver; Suribhatla, Srinivas; Prettyman, Richard; Murray, Jonathan; Baillon, Sarah; Bhattacharyya, Sagnik

    2014-01-01

    The endocannabinoid system (ECS) is now recognised as an important modulator of various central nervous system processes. More recently, an increasing body of evidence has accumulated to suggest antioxidant, anti-inflammatory and neuroprotective roles of ECS. In this review we discuss the role and therapeutic potential of ECS in neurodegenerative disorders such as Alzheimer's disease (AD), Parkinson's disease, multiple sclerosis, Huntington's disease, Tourette's syndrome, brain ischemia and amyotrophic lateral sclerosis (ALS). Elements of the ECS, such as fatty acid amide hydrolase or the cannabinoid receptors are now considered as promising pharmacological targets for some diseases. Although still preliminary, recent reports suggest that modulation of the ECS may constitute a novel approach for the treatment of AD. There are windows of opportunity in conditions caused by acute events such as trauma and ischemia as well in conditions that may involve altered functionality of the target receptors of the ECS, such as in AD. The ECS changes in Parkinson's disease could be compensatory as well as pathogenic of the illness process and needs further understanding and clinical studies are still in the preliminary stage. There is not enough evidence to support use of cannabinoids in treating Huntington's disease, tics and obsessive compulsive behaviour in Tourette's syndrome. Evidence on therapeutic use of cannabinoids in multiple sclerosis and ALS is currently limited. A major challenge for future research is the development of novel compounds with more selectivity for various components of the ECS which could target different neurotoxic pathways and be used in combination therapy.

  6. Spatial coincidence of rapid inferred erosion with young metamorphic massifs in the Himalayas

    Science.gov (United States)

    Finlayson, David P.; Montgomery, David R.; Hallet, Bernard

    2002-03-01

    A spatially distributed rate-of-erosion index (EI) based on models of bedrock river incision documents a strong spatial correspondence between areas of high erosion potential and young metamorphic massifs as well as structural highs throughout the Himalayas. The EI is derived from slopes and drainage areas calculated from a hydrologically corrected digital elevation model (GTOPO30) combined with precipitation data (IIASA) to generate synthetic annual stream discharges. These variables drive three generalized process models to produce EI maps that, while differing in detail, provide an internally consistent, spatially continuous index of large-scale erosion rates. The large spatial variation in potential erosion rates in the Himalayas suggested by the EI patterns contrasts with the uniform convergence of the Indian subcontinent. If these EI gradients persist through time, they support the emerging view of a positive feedback between localized, rapid erosion and upward advection of lower crust.

  7. Arc parallel extension in Higher and Lesser Himalayas, evidence from western Arunachal Himalaya, India

    Indian Academy of Sciences (India)

    Sharmistha De Sarkar; George Mathew; Kanchan Pande

    2013-06-01

    The existence of E–W extensional features from northeast (NE) Himalaya is poorly documented. Our investigation in the western part of Arunachal Himalaya provides evidences of active Quaternary E–W arc-parallel extensional features in the Higher and Lesser Himalayas. They are represented by arcperpendicular normal faults and arc-parallel sinistral strike-slip faults. We discuss the occurrences of these arc-parallel extensional features in terms of oblique convergence and radial expansion models. The partitioning of stress due to oblique convergence is argued based on evidences of left-lateral slip in NEHimalaya, right-lateral slip in NW-Himalaya and absence of translation in the central part. The amount of arc-parallel extension in the hinterland regions is correlated to the amount of radial shortening in the foreland. The computation of arc-parallel extension in the NE Himalayan arc is carried out by defining a small-circle centered at 88° 39′ ± 0.7′E longitude and 33° 40′ ± 0.6′N latitude having a radius of 770.7 ± 15.1 km, for the segment between 92° 01′ and 95° 16′E longitudes. The amount of arc-parallel extension estimated is ∼110 km for the NE Himalayan segment. Our result agrees closely with the 104 km extension determined based on geodetically computed extension rate and age of initiation of rifting in southern Tibet.

  8. Potential of Air-Propelled Abrasives for Selective Weed Control

    Science.gov (United States)

    Novel forms of selective weed control are needed by many types of growers, but especially organic growers who are restricted from using synthetic herbicides. Abrasive grit made from corn cobs was expelled from a sand blaster at 517 kPa pressure and aimed at seedlings of common lambsquarters and corn...

  9. Potential consequences of selection on gestation length on Holstein performance

    Science.gov (United States)

    Genetic evaluations for gestation length (GL) for Holstein service sires were studied to determine their effectiveness in predicting GL in an independent data set. Consequences of selection on GL were assessed also by examining correlated changes in milk and fitness traits. Holstein bulls, each with...

  10. Identification of seismically susceptible areas in western Himalaya using pattern recognition

    Indian Academy of Sciences (India)

    Mridula; Amita Sinvhal; Hans Raj Wason

    2016-06-01

    Seismicity in the western Himalayas is highly variable. Several historical and instrumentally recordeddevastating earthquakes originated in the western Himalayas which are part of the Alpine–Himalayanbelt. Earthquakes cause tremendous loss of life and to the built environment. The amount of loss interms of life and infrastructure has been rising continuously due to significant increase in population andinfrastructure. This study is an attempt to identify seismically susceptible areas in western Himalaya,using pattern recognition technique. An area between latitude 29◦–36◦N and longitude 73◦–80◦E wasconsidered for this study. Pattern recognition starts with identification, selection and extraction of featuresfrom seismotectonic data. These features are then subjected to discriminant analysis and the studyarea was classified into three categories, viz., Area A: most susceptible area, Area B: moderately susceptiblearea, and Area C: least susceptible area. Results show that almost the entire states of HimachalPradesh and Uttarakhand and a portion of Jammu & Kashmir are classified as Area A, while most ofJammu & Kashmir is classified as Area B and the Indo-Gangetic plains are classified as Area C.

  11. A study of algal biomass potential in selected Canadian regions.

    Energy Technology Data Exchange (ETDEWEB)

    Passell, Howard David; Roach, Jesse Dillon; Klise, Geoffrey T.

    2011-11-01

    A dynamic assessment model has been developed for evaluating the potential algal biomass and extracted biocrude productivity and costs, using nutrient and water resources available from waste streams in four regions of Canada (western British Columbia, Alberta oil fields, southern Ontario, and Nova Scotia). The purpose of this model is to help identify optimal locations in Canada for algae cultivation and biofuel production. The model uses spatially referenced data across the four regions for nitrogen and phosphorous loads in municipal wastewaters, and CO{sub 2} in exhaust streams from a variety of large industrial sources. Other data inputs include land cover, and solar insolation. Model users can develop estimates of resource potential by manipulating model assumptions in a graphic user interface, and updated results are viewed in real time. Resource potential by location can be viewed in terms of biomass production potential, potential CO{sub 2} fixed, biocrude production potential, and area required. The cost of producing algal biomass can be estimated using an approximation of the distance to move CO{sub 2} and water to the desired land parcel and an estimation of capital and operating costs for a theoretical open pond facility. Preliminary results suggest that in most cases, the CO{sub 2} resource is plentiful compared to other necessary nutrients (especially nitrogen), and that siting and prospects for successful large-scale algae cultivation efforts in Canada will be driven by availability of those other nutrients and the efficiency with which they can be used and re-used. Cost curves based on optimal possible siting of an open pond system are shown. The cost of energy for maintaining optimal growth temperatures is not considered in this effort, and additional research in this area, which has not been well studied at these latitudes, will be important in refining the costs of algal biomass production. The model will be used by NRC-IMB Canada to identify

  12. Tree ring imprints of long-term changes in climate in western Himalaya, Indi

    Indian Academy of Sciences (India)

    R R Yadav

    2009-11-01

    Tree-ring analyses from semi-arid to arid regions in western Himalaya show immense potential for developing millennia long climate records. Millennium and longer ring-width chronologies of Himalayan pencil juniper (Juniperus polycarpos), Himalayan pencil cedar (Cedrus deodara) and Chilgoza pine (Pinus gerardiana) have been developed from different sites in western Himalaya. Studies conducted so far on various conifer species indicate strong precipitation signatures in ring-width measurement series. The paucity of weather records from stations close to tree-ring sampling sites poses difficulty in calibrating tree-ring data against climate data especially precipitation for its strong spatial variability in mountain regions. However, for the existence of strong coherence in temperature, even in data from distant stations, more robust temperature reconstructions representing regional and hemispheric signatures have been developed. Tree-ring records from the region indicate multi-century warm and cool anomalies consistent with the Medieval Warm Period and Little Ice Age anomalies. Significant relationships noted between mean premonsoon temperature over the western Himalaya and ENSO features endorse utility of climate records from western Himalayan region in understanding long-term climate variability and attribution of anthropogenic impact.

  13. 喜马拉雅山地区冰川湖溃决灾害隐患遥感调查及影响因素分析%Remote sensing investigation and influence factor analysis of glacier lake outburst potential in the Himalayas

    Institute of Scientific and Technical Information of China (English)

    刘春玲; 童立强; 祁生文; 张世殊; 郑博文

    2016-01-01

    喜马拉雅山地区的冰川湖(简称“冰湖”)受形成条件和自然环境的影响,往往会发生溃决,造成洪水和泥石流灾害,严重威胁人类生产和生活、生存与发展,成为该地区一重大地质灾害隐患。采用QuickBird和ETM等卫星遥感数据,结合野外考察,研究喜马拉雅山地区冰湖溃决灾害隐患后认为:①喜马拉雅山地区的冰湖在区域分布上具有由东南向西北逐步递减的趋势,冰湖分布最多的是山南、日喀则、林芝和阿里地区,分布密度最大的是山南地区的洛扎一带;②喜马拉雅山地区存在19个溃决灾害隐患的冰湖,均为冰川终碛湖,其中13个湖存在重大溃决灾害隐患,6个存在较大溃决灾害隐患;③引起冰川终碛湖溃决的激发因素较多,其中冰湖周围的冰崩、雪崩、基岩崩塌和滑坡入湖涌浪溃坝是最重要的原因。研究结果对西藏地区冰湖溃决灾害的预警与防治具有重要意义。%Under the impact of formation conditions and natural environment , moraine -dammed lake outbursts take place frequently and then give rise to floods and mudslides , which menaces people's production , life, survival and development and becomes one of the great geohazard hidden dangers in the Himalayas .Using QuickBird and ETM data of remote sensing satellite and combining the investigations in field work , the authors studied the glacier lake outburst potential .The research results show that the areal distribution of glacier lakes presents a trend of decrease gradually from SE to NW in the Himalayas .Most of the glacier lakes are distributed in Shannan , Shigatse , Nyingchi and Ngari .The region of maximal distribution density is Lho -brag area of Shannan .It can be found that there are nineteen glacier lakes , all of which are moraine -dammed lakes that have outburst hazard potential . Among the nineteen glacier lakes , there are 13 glacier lakes having great

  14. The Diversity Potential of Relay Selection with Practical Channel Estimation

    CERN Document Server

    Michalopoulos, Diomidis S; Schober, Robert; Karagiannidis, George K

    2011-01-01

    We investigate the diversity order of decode-and-forward relay selection in Nakagami-m fading, in cases where practical channel estimation techniques are applied. In this respect, we introduce a unified model for the imperfect channel estimates, where the effects of noise, time-varying channels, and feedback delays are jointly considered. Based on this model, the correlation between the actual and the estimated channel values, \\rho, is expressed as a function of the signal-to-noise ratio (SNR), yielding closed-form expressions for the overall outage probability as a function of \\rho. The resulting diversity order and power gain reveal a high dependence of the performance of relay selection on the high SNR behavior of \\rho, thus shedding light onto the effect of channel estimation on the overall performance. It is shown that when the channel estimates are not frequently updated in applications involving time-varying channels, or when the amount of power allocated for channel estimation is not sufficiently high...

  15. Comparison of potentials between genotype-based selection and genotypic value-based selection of quantitative traits

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    According to the difference of selection criteria, methods of marker-assisted selection (MAS) of quantitative traits can be divided into genotype-based selection (GS) and genotypic value-based selection (GVS). By means of computer simulation, potentials of the two methods were compared. Results showed that the two methods had similar basic laws and their efficiencies were not significantly different except that GS behaved better in the case where the number of QTLs was large and QTL effects were equal. From the application point of view, combination of GS and GVS should be the development direction of MAS research in the future.

  16. Sample Selected Averaging Method for Analyzing the Event Related Potential

    Science.gov (United States)

    Taguchi, Akira; Ono, Youhei; Kimura, Tomoaki

    The event related potential (ERP) is often measured through the oddball task. On the oddball task, subjects are given “rare stimulus” and “frequent stimulus”. Measured ERPs were analyzed by the averaging technique. In the results, amplitude of the ERP P300 becomes large when the “rare stimulus” is given. However, measured ERPs are included samples without an original feature of ERP. Thus, it is necessary to reject unsuitable measured ERPs when using the averaging technique. In this paper, we propose the rejection method for unsuitable measured ERPs for the averaging technique. Moreover, we combine the proposed method and Woody's adaptive filter method.

  17. Selection of materials with potential in sensible thermal energy storage

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez, A.I.; Martinez, M.; Segarra, M. [Department of Materials Science and Metallurgical Engineering, Universitat de Barcelona, Marti i Franques 1, 08028 Barcelona (Spain); Martorell, I.; Cabeza, L.F. [GREA Innovacio Concurrent, Edifici CREA, Universitat de Lleida, Pere de Cabrera s/n, 25001 Lleida (Spain)

    2010-10-15

    Thermal energy storage is a technology under investigation since the early 1970s. Since then, numerous new applications have been found and much work has been done to bring this technology to the market. Nevertheless, the materials used either for latent or for sensible storage were mostly investigated 30 years ago, and the research has lead to improvement in their performance under different conditions of applications. In those years a significant number of new materials were developed in many fields other than storage and energy, but a great effort to characterize and classify these materials was done. Taking into account the fact that thousands of materials are known and a large number of new materials are developed every year, the authors use the methodology for materials selection developed by Prof. Ashby to give an overview of other materials suitable to be used in thermal energy storage. Sensible heat storage at temperatures between 150 and 200 C is defined as a case study and two different scenarios were considered: long term sensible heat storage and short term sensible heat storage. (author)

  18. Metabolic Potential of the Deep Subseafloor at Selected Convergent Margins

    Science.gov (United States)

    Cardace, D.; Amend, J. P.; Morris, J. D.

    2005-12-01

    The cold subseafloor is an extreme environment in which microbial metabolism appears to operate slowly but persistently over space and time. At convergent margins, subseafloor microbial communities experience diffuse flow of aqueous fluids through sediment interstices and variable flow of deeply sourced, advecting fluids. When these fluids mix, geochemical disequilibria are established, and may serve as energy sources in microbial metabolism. This study contrasts the metabolic potential of four near trench sedimentary environments associated with the Costa Rica, Cascadia, Nankai, and Izu-Bonin-Marianas subduction zones, which span much of the global range of water depths (~ 2500 to ~ 5800 m) and thermal structure (heat flow at seafloor ~ 15 to ~ 140 mW/m2) outboard of subduction zones. Geochemical data (pH, NH4+, Na+, K+, Fe2+, Ca2+, Mg2+, HCO3-, Cl-, SO42-, SiO2 (aq), CH4 (aq), H2 (aq), PO43-, HS-, and CH3COO-) collected during Ocean Drilling Program Legs 146, 170, 185, 190, and 201 are used in Gibbs free energy minimization calculations to model the bioenergetic potential of key metabolic reactions. At the four sites, pH values are 7.3-8.2, alkalinity values are 1 to 24 mM, and sulfate values are 0 to 30 mM. Notable site-specific differences exist in NH4+ (ranging two orders of magnitude in concentration) and salinity (with reported values up to 40 psu at Izu). The specific reactions considered are: (1) CO2 driven methanogenesis, (2) acetate driven methanogenesis, (3) methanotrophy coupled to sulfate reduction, (4) acetate oxidation coupled to sulfate reduction, (5) acetate oxidation coupled with nitrate reduction, (6) acetate oxidation coupled with ferric iron reduction. The standard Gibbs free energies are combined with the in situ geochemical parameters to calculate overall Gibbs free energies in deep subseafloor environments. In all cases, ferric iron reduction coupled with acetate oxidation yields the greatest energy (~-1600 kJ/mol), followed by nitrate

  19. Controls on channel width in an intermontane valley of the frontal zone of the northwestern Himalaya

    Science.gov (United States)

    Parida, Sukumar; Tandon, S. K.; Singh, Vimal

    2017-02-01

    Channel width is an important parameter of the hydraulic geometry of a river and can be linked to the tectonic, topographic, lithologic, and climatic controls in a particular reach. As such, variations in channel width can be the result of one or many factors acting at a specific location. For the rivers flowing in the intermontane valleys along the frontal Himalaya, active tectonics plays a major role in controlling their geometry by providing the space, energy, and sediment. Dehra Dun is an intermontane valley in the northwestern Himalaya where the rivers have their source in the Lesser Himalaya and Sub-Himalaya; they show remarkable variability in the channel width along their course. In this work, we have attempted to identify and evaluate the relative importance of various controlling factors on the channel width of these drainage systems. We selected 20 streams (six North Flank rivers - NFRs; two Main Axial rivers - MARs; twelve South Flank rivers - SFRs) flowing in the valley. In the hilly stretches, the NFRs flow over the Lesser Himalaya and the SFRs flow over the poorly consolidated upper Siwalik gravelly sediments. Channel width in the mountainous region varies generally from 5 to 30 m. The SFRs that have smaller catchments are relatively wider than the NFRs in the mountainous areas. In the Dun, the width variation is mostly between 50 and 400 m. The NFRs show widening in their middle stretches except for the Tons River, which is wide in its lower stretch. Channels widen as they cross the structural zones (i.e., the Main Boundary Thrust (MBT), the Santaurgarh Thrust (ST), and the Bhauwala Thrust (BT)) as a result of the change in the gradient across the structures. Large sediment supply generated by mass wasting processes from the weak zones (i.e., fault-related zones) and uplifted surfaces make the river transport limited, resulting in the deposition of the sediments. Consequently, channel bed armoring in these gravel-bed rivers protects the channel

  20. Highly Selective Artificial K(+) Channels: An Example of Selectivity-Induced Transmembrane Potential.

    Science.gov (United States)

    Gilles, Arnaud; Barboiu, Mihail

    2016-01-13

    Natural KcsA K(+) channels conduct at high rates with an extraordinary selectivity for K(+) cations, excluding the Na(+) or other cations. Biomimetic artificial channels have been designed in order to mimick the ionic activity of KcSA channels, but simple artificial systems presenting high K(+)/Na(+) selectivity are rare. Here we report an artificial ion channel of H-bonded hexyl-benzoureido-15-crown-5-ether, where K(+) cations are highly preferred to Na(+) cations. The K(+)-channel conductance is interpreted as arising in the formation of oligomeric highly cooperative channels, resulting in the cation-induced membrane polarization and enhanced transport rates without or under pH-active gradient. These channels are selectively responsive to the presence of K(+) cations, even in the presence of a large excess of Na(+). From the conceptual point of view, these channels express a synergistic adaptive behavior: the addition of the K(+) cation drives the selection and the construction of constitutional polarized ion channels toward the selective conduction of the K(+) cation that promotes their generation in the first place.

  1. Pyrometallurgical slags as a potential source of selected metals recovery

    Directory of Open Access Journals (Sweden)

    K. Nowińska

    2014-10-01

    Full Text Available Complex analysis of concentration and form of occurrence such metals as Zn, Pb, Fe and Cu in slags formed during a current zinc production in the Imperial Smelting Process (ISP is a possible basis for development of optimal recovery technology. For this purpose studies of slags from the current production of the Shaft Furnace Unit and of the Lead Refining of the “Miasteczko Śląskie” Zinc Smelting Plant were carried out. The studies results show that slags includes high concentrations of: Zn from 0,064 % to 1,680 %, Pb from 10,56 % to 50,71 %, Fe from 0,015 % to 2,576 %, Cu from 7,48 % to 64,95 %, and change in a broad range. This slags show significant heterogeneity, caused by intermetallic phases (Zn - Pb, Cu - Zn, Cu - Pb formed on the surface thereof. It is so possible that slag can be a potential source of this metals recovery.

  2. Potential assessment of genome-wide association study and genomic selection in Japanese pear Pyrus pyrifolia

    OpenAIRE

    Iwata, Hiroyoshi; Hayashi, Takeshi; Terakami, Shingo; Takada, Norio; Sawamura, Yutaka; Yamamoto, Toshiya

    2013-01-01

    Although the potential of marker-assisted selection (MAS) in fruit tree breeding has been reported, bi-parental QTL mapping before MAS has hindered the introduction of MAS to fruit tree breeding programs. Genome-wide association studies (GWAS) are an alternative to bi-parental QTL mapping in long-lived perennials. Selection based on genomic predictions of breeding values (genomic selection: GS) is another alternative for MAS. This study examined the potential of GWAS and GS in pear breeding w...

  3. Trypanosomosis: Potential driver of selection in African cattle

    Directory of Open Access Journals (Sweden)

    Anamarija eSmetko

    2015-04-01

    Full Text Available Trypanosomosis is a serious cause of reduction in productivity of cattle in tsetse-fly infested areas. Baoule and other local Taurine cattle breeds in Burkina Faso are trypanotolerant. Zebuine cattle, which are also kept there are susceptible to trypanosomosis but bigger in body size. Farmers have continuously been intercrossing Baoule and Zebu animals to increase production and disease tolerance. The aim of this study was to compare levels of zebuine and taurine admixture in genomic regions potentially involved in trypanotolerance with background admixture of composites to identify differences in allelic frequencies of tolerant and non tolerant animals. The study was conducted on 214 animals (90 Baoule, 90 Zebu and 34 composites, genotyped with 25 microsatellites across the genome and with 155 SNPs in 23 candidate regions. Degrees of admixture of composites were analyzed for microsatellite and SNP data separately. Average Baoule admixture based on microsatellites across the genomes of the Baoule-Zebu composites was 0.31, which was smaller than the average Baoule admixture in the trypanosomosis candidate regions of 0.37 (P=0.15. Fixation index FST measured in the overall genome based on microsatellites or with SNPs from candidate regions indicates strong differentiation between breeds. Nine out of 23 regions had FST ≥ 0.20 calculated from haplotypes or individual SNPs. The levels of admixture were significantly different from background admixture, as revealed by microsatellite data, for six out of the nine regions. Five out of the six regions showed an excess of Baoule ancestry. Information about best levels of breed composition would be useful for future breeding activities, aiming at trypanotolerant animals with higher productive capacity.

  4. Selective attention to orientation and closure: An event-related potential study

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Event-related potentials (ERPs) were recorded when the subjects attended selectively to stimuli in one visual field and responded to the targets including designated feature (orientation or closure) value. Attention to spatial location elicited enlarged P1 and N1 at posterior electrodes contralateral to the stimulus location, whereas selection to orientation or closure elicited selection negativity (SN) and a late negative component (LNC). The selection of spatial location was prior to the selection of orientation or closure. SN was elicited only by the stimuli in the attended visual field, suggesting that the selection of orientation and closure are contingent on the prior selection of location. Moreover, the onset latency of SN was earlier for closure selection than for orientation selection, indicating that the processing of closure occurred earlier than the processing of orientation. The results are consistent with the early-selection theories of attention and provide psycho-physiological evidence for the topology theory of visual perception.

  5. Selective attention to orientation and closure: An event- related potential study

    Institute of Scientific and Technical Information of China (English)

    傅世敏; 范思陆; 陈霖

    2000-01-01

    Event-related potentials (ERPs) were recorded when the subjects attended selectively to stimuli in one visual field and responded to the targets including designated feature (orientation or closure) value. Attention to spatial location elicited enlarged PI and Nl at posterior electrodes contralater-al to the stimulus location, whereas selection to orientation or closure elicited selection negativity (SN) and a late negative component (LNC). The selection of spatial location was prior to the selection of orientation or closure. SN was elicited only by the stimuli in the attended visual field, suggesting that the selection of orientation and closure are contingent on the prior selection of location. Moreover, the onset latency of SN was earlier for closure selection than for orientation selection, indicating that the processing of closure occurred earlier than the processing of orientation. The results are consistent with the early-selection theories of attention and provide psycho-physiological evidence

  6. EVALUATION OF GARHWAL HIMALAYA WILD EDIBLE TUBER DIOSCOREA DELTOIDEA

    Directory of Open Access Journals (Sweden)

    Chandra Subhash

    2012-03-01

    Full Text Available The Uttarakhand is highly enriched with edible wild tubers. Such tubers are highly potential with medicinal value and nutritional value due to the presence of bio-actives. These tubers are consumed by local inhabitants to play a significant role as supplementary food. The present study is aimed at evaluating the nutritional value, successive extraction, thin layer chromatography of medicinal plant, Dioscorea deltoidea. It is a popular wild edible tubers bearing plant of Indian Himalaya having good nutritional and medicinal potential. These will be the best source of the nutraceuticals. Since tubers are richer in micronutrients and bioactive secondary metabolites, The medicinal plant tuber contain ash value, (total ash 3.34 ± 0.15%, moisture 58.92±0.10%, crude fat 0.60±0.20% and crude fiber 7.50±0.14%, the successive extractive values were studied fresh part weight. The preliminary phytochemical analysis test showed the presence of carbohydrates and glycosides, alkaloid, flavonoids, saponins, tannins, unsaturated triterpenoids and sterol, resin.

  7. Snow cover changes in the Hindu-Kush Karakoram Himalaya

    Science.gov (United States)

    Terzago, Silvia; Von Hardenberg, Jost; Palazzi, Elisa; Provenzale, Antonello

    2013-04-01

    Snow cover plays a key role in high-altitude environments, and changes in the snow spatial/temporal distribution and thickness affect energy, radiation and water budgets at the Earth's surface. In particular, a reduction in the snow amount has a direct effect on the availability and seasonal distribution of water resources. This is especially true in areas such as the Hindu-Kush Karakoram Himalaya (HKKH) region, which provides water to about 1.5 Billion peoples in India, Nepal, Pakistan and China. Despite its importance, knowledge on snow dynamics in the HKKH region is still incomplete, owing also to sparse and sporadic surface observations. In this work, we used simulations from Global Climate Models (GCMs) to gain information on snowpack characteristics and climatology in the HKKH region. We selected a set of GCM snow depth datasets from the CMIP5 ensemble, esploring snow abundance and distribution at monthly scale. In order to investigate how well Global Climate Models represent the snow climatology, we compared the results with the ERA-Interim reanalysis, used as an approximation to the real conditions. After exploring the average snow conditions in the last decades, we analyzed the effects of climate change in the HKKH region by using an ensemble of future snow projections obtained from different GCMs and in different climate change scenarios.

  8. Response of monsoon variability in Himalayas to global warming

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Reconstructed annual net accumulation from the Dasuopu ice core recovered in Himalayas, with a good correlation to Indian monsoon, reflects a major precipitation trend in central Himalayas. The Dasuopu accumulation (DSP An) also shows a strong correlation to the Northern Hemispheric temperature. Generally, as the Northern Hemispheric temperature increases by 0.1 K, the accumulation decreases by about 90 mm and vise versa. Under the condition of global warming, especially since 1920, the Northern Hemispheric mean temperature has increased by about 0.5 K, whereas accumulation in Dasuopu ice core has decreased by about 450 mm. According to the relationship between accumulation and temperature, a scenario prediction of monsoon rainfall in central Himalayas is made.

  9. Himalayas as seen from STS-66 shuttle Atlantis

    Science.gov (United States)

    1994-01-01

    View is southeastward across China (Tibet), half of Nepal and India. The partly frozen lake near the center of the frame is Pei-Ku T'so ('Bos-tie Lake'). The central Himalaya stretches from Mount Everest on the left past Annapurna on the right. Large tributaries converge to form the Ganges River, flowing through the lowland basin south of the Himalaya. This photograph illustrates the rain shadow effect of the Himalaya Chain; wet, warm air from the Indian Ocean is driven against the mountains, lifted, and drained of water that forms ice caps, the abundant rivers, and forests of the foothills. In contrast the high plateau of Tibet is arid, composed largely of topographically-closed basins because stream flow is inadequate to form integrated drainage networks.

  10. Probiotic attributes of indigenous Lactobacillus spp. isolated from traditional fermented foods and beverages of north-western Himalayas using in vitro screening and principal component analysis.

    Science.gov (United States)

    Kumari, Anila; Angmo, Kunzes; Monika; Bhalla, Tek Chand

    2016-05-01

    The present research was designed to explore indigenous probiotic Lactic acid bacteria from traditional fermented foods and beverages of North-western Himalayas for their probiotic potential. It was achieved through a step-by step approach focused on the technological characterization, evaluation of the probiotic traits and adherence ability. Fifty one LAB isolates from traditional fermented foods and beverages were initially screened for their technological properties and among them twenty isolates were selected. These isolates were further characterized and identified using 16S rRNA gene sequencing as Lactobacillus brevis (7 isolates), Lactobacillus casei (5), Lactobacillus paracasei (2), Lactobacillus buchneri (1), Lactobacillus plantarum (1) and Lactobacillus sp. (3). Identified isolates were evaluated by in vitro methods including survival in gastrointestinal tract, antibiotic susceptibility, antimicrobial activity, cell surface characteristics, exopolysacharride production and haemolytic activity. The results of these experiments were used as input data for Principal Component Analysis; thus, to select the most promising probiotic isolates. Three isolates (L. brevis PLA2, L. paracasei PLA8 and L. brevis PLA16) were found to be most technological relevant and promising probiotic candidates in comparison to commercial probiotic strains. L. brevis PLA2 was selected as best isolate with probiotic potential by in vitro adherence to the human intestinal HT-29 cell line.

  11. Decrease, Increase or Stability? Glacier Response to Climate Change in the Trans-Himalayas of Ladakh, Northern India

    Science.gov (United States)

    Schmidt, Susanne; Nüsser, Marcus

    2010-05-01

    The eastern and central parts of the Greater Himalayas display a general picture of rapidly melting glaciers, whereas the glaciers in the western Himalayas, Hindu Kush and Karakorum show a more differentiated response to climate change. It includes individual advancing glaciers and relatively stable snout positions. The Trans-Himalayan region of Ladakh is possibly located at the interface between shrinking and advancing or stable glaciers. The region is characterized by cold and arid conditions (mean annual air temperature amounts 5.6 °C and precipitation 93 mm in Leh, 3545 m a.s.l.), while the influence of the monsoon is rather limited. Due to low summer precipitation and the variability of winter snow fall, glaciers largely determine the potentials and limitations of irrigated crop cultivation, forming the primary basis of subsistence agriculture and regional food security. The glaciers of Ladakh are located above 5200 m a.s.l. and according to their small size (generally less than 2 km²), their response to climate change is expected to be direct and predictable. To detect and to quantify glacier changes in different aspects of the NNW-SSE oriented Kang Yatze Massif (6401 m a.s.l.), which is sandwiched between the Zanskar and Stok Ranges, multi-temporal and multi-scale remote sensing data were used. In order to map the changes of glacier covered areas two panchromatic Corona images from 1969 were compared to a high resolution panchromatic Worldview image from 2009. The data gap of the 40 years period was filled with Spot images (1991, 2006), and several Landsat and Aster data. To identify and quantify the glacierized areas a semi-automatic thresholding approach was applied for the co-registered multi-spectral datasets. Additionally, the delineation of glaciers was manually digitized on the panchromatic images. First results for the time period between 1969 and 2009 reveal a minor decrease of almost all investigated glaciers in the Kang Yatze Massif. In order to

  12. Changing glacial lakes and associated outburst floods risks in Nanda Devi Biosphere Reserve, Indian Himalaya

    Science.gov (United States)

    Mal, S.; Singh, R. B.

    2014-09-01

    Glacial lakes and associated outburst floods (GLOFs) have increased in the Himalayan region due to climate change during the last century that has led to huge losses to society. Therefore, the present study was undertaken to map glacial lakes, their increasing extent, and associated damage potential in Nanda Devi Biosphere Reserve (NDBR), Indian Himalaya. The glacial lakes were mapped on Landsat TM (3 November, 2009 and 6 November 2010) and Landsat MSS satellite images (15 November 1976 and 26 October 1979) to assess their changing area. Potential GLOFs sites have been identified and studied for their damage potentials using site characteristics and past occurrence of GLOFs. A total of 35 lakes were mapped, of which 14 lakes are located at more than 4500 m. The size and damage potentials of lakes have increased. Some lakes grew so much that they merged to form a big lake. All of these are potential GLOFs and can cause severe damage to society.

  13. Atmospheric brown clouds reach the Tibetan Plateau by crossing the Himalayas

    Directory of Open Access Journals (Sweden)

    Z. L. Lüthi

    2015-06-01

    Full Text Available The Himalayas and the Tibetan Plateau region (HTP, despite being a remote and sparsely populated area, is regularly exposed to polluted air masses with significant amounts of aerosols including black carbon. These dark, light-absorbing particles are known to exert a great melting potential on mountain cryospheric reservoirs through albedo reduction and radiative forcing. This study combines ground-based and satellite remote sensing data to identify a severe aerosol pollution episode observed simultaneously in central Tibet and on the southern side of the Himalayas during 13–19 March 2009 (pre-monsoon. Trajectory calculations based on the high-resolution numerical weather prediction model COSMO are used to locate the source regions and study the mechanisms of pollution transport in the complex topography of the HTP. We detail how polluted air masses from an atmospheric brown cloud (ABC over South Asia reach the Tibetan Plateau within a few days. Lifting and advection of polluted air masses over the great mountain range is enabled by a combination of synoptic-scale and local meteorological processes. During the days prior to the event, winds over the Indo-Gangetic Plain (IGP are generally weak at lower levels, allowing for accumulation of pollutants and thus the formation of ABCs. The subsequent passing of synoptic-scale troughs leads to southwesterly flow in the middle troposphere over northern and central India, carrying the polluted air masses across the Himalayas. As the IGP is known to be a hotspot of ABCs, the cross-Himalayan transport of polluted air masses may have serious implications for the cryosphere in the HTP and impact climate on regional to global scales. Since the current study focuses on one particularly strong pollution episode, quantifying the frequency and magnitude of similar events in a climatological study is required to assess the total impact.

  14. Temporal and spatial variations in erosion rate in the Sikkim Himalaya as a function of climate and tectonics

    Science.gov (United States)

    Abrahami, Rachel; Huyghe, Pascale; van der Beek, Peter; Carcaillet, Julien

    2014-05-01

    The Tista River is a major tributary of the Brahmaputra drainage system (Eastern Himalaya). Its headwaters are located in the glaciated northernmost parts of the Sikkim and its catchment area amounts to more than 12,000 km2 including a depositional megafan (extending mostly in Bangladesh and West Bengal-India). The Tista has recently incised its megafan at the topographic front of the mountain range by about 30 meters. Neither the timing of deposition/incision of the megafan sediments, nor the erosion rates of the source areas as well as their potential relationships, have been investigated in detail. Comparing these data is essential to distinguish between a climatic and/or tectonic control of the evolution of the Sikkim Himalaya and piedmont. To constrain erosion rates in the hinterland at different temporal scales (respectively millenial and geological timescales), we report cosmogenic nuclide (10Be) and thermochronological (apatite fission-tracks) data on modern river sands. Results were mapped to evidence spatial variations of erosion/exhumation rates in the Tista catchment. Cosmogenic nuclides were also used to date the onset of incision of the megafan and relate it to potential changes in hinterland erosion. In addition, isotope geochemistry (ɛNd and 87Sr/86Sr) performed on modern river sands and Late-Quaternary megafan sediments allows characterizing the isotopic signature of the different source areas and constraining variations in provenance of the Tista megafan deposits through time in response to changing climatic conditions. Results show that the Tista fan deposits are mainly sourced from the High Himalayan Crystalline domain with excursions more influenced by the Lesser Himalaya domain. These data provide a new comprehensive view on modern erosion and long-term exhumation of the Sikkim Himalaya. This study of a "closed system" will help our knowledge and understanding of erosional processes and sediment fluxes in mountainous environments as a

  15. Active Faults of the Northwest Himalaya: Pattern, Rate, and Timing of Surface Rupturing Earthquakes

    Science.gov (United States)

    Yule, J.; Madden, C.; Gavillot, Y.; Hebeler, A.; Meigs, A.; Hussein, A.; Malik, M.; Bhat, M.; Kausar, A.; Ramzan, S.; Sayab, M.; Yeats, R. S.

    2012-12-01

    2 surface rupturing events in the latest Quaternary and a shortening rate of 0.3 to 1.3 mm/yr. The active structures described above can account for 15 to 50% of India-Asia convergence, with up to ~20% of the shortening occurring on structures within the orogenic belt. Seismicity in the NW Himalaya is also broadly distributed but tends to concentrate in several places (e.g., the Indus-Kohistan and Hazara Lower seismic zones). Like in the central Himalaya, the zones of seismicity in the NW Himalaya may locate regions where interseismic strain accumulates, possibly in the middle crust along thrust ramps, and is released during large (>Mw 7.5) events. These relatively infrequent earthquakes likely activate portions (all?) of the plate boundary detachment fault and/or the within-plate fault systems. It may be possible for the region to generate earthquakes as large as >Mw 8.5, taking into account a reasonable average slip value and maximum possible rupture area. Recognition of internal surface-rupturing reverse faults indicates probabilistic models for seismic hazards in the NW Himalaya ought to account for great earthquakes on the Main Himalayan thrust (the basal detachment), moderate earthquakes on upper plate faults, and potentially events in the down-going Indian plate.

  16. Selective in situ potential-assisted SAM formation on multi electrode arrays

    Science.gov (United States)

    Haag, Ann-Lauriene; Toader, Violeta; Lennox, R. Bruce; Grutter, Peter

    2016-11-01

    The selective modification of individual components in a biosensor array is challenging. To address this challenge, we present a generalizable approach to selectively modify and characterize individual gold surfaces in an array, in an in situ manner. This is achieved by taking advantage of the potential dependent adsorption/desorption of surface-modified organic molecules. Control of the applied potential of the individual sensors in an array where each acts as a working electrode provides differential derivatization of the sensor surfaces. To demonstrate this concept, two different self-assembled monolayer (SAM)-forming electrochemically addressable ω-ferrocenyl alkanethiols (C11) are chemisorbed onto independent but spatially adjacent gold electrodes. The ferrocene alkanethiol does not chemisorb onto the surface when the applied potential is cathodic relative to the adsorption potential and the electrode remains underivatized. However, applying potentials that are modestly positive relative to the adsorption potential leads to extensive coverage within 10 min. The resulting SAM remains in a stable state while held at potentials <200 mV above the adsorption potential. In this state, the chemisorbed SAM does not significantly desorb nor do new ferrocenylalkythiols adsorb. Using three set applied potentials provides for controlled submonolayer alkylthiol marker coverage of each independent gold electrode. These three applied potentials are dependent upon the specifics of the respective adsorbate. Characterization of the ferrocene-modified electrodes via cyclic voltammetry demonstrates that each specific ferrocene marker is exclusively adsorbed to the desired target electrode.

  17. The Himalaya-Tibet System: A Natural laboratory for continental collision and seismogenesis

    Science.gov (United States)

    Meltzer, A.; Brown, L. D.; Song, X.

    2015-12-01

    The Himalaya-Tibet system remains one of the best places to study continental dynamics, mountain building, and nucleation of great earthquakes. Over the past several decades, numerous research projects have used the Himalaya and Tibet as a natural laboratory to investigate the process of continental collision. Much has been learned about the orogen, including the remarkable along-strike continuity of many features: the orogen's basic geology and structure, the morphology and drainages of the Himalayan arc, and the apparent symmetry of the syntaxes at either end. At the same time, numerous focused studies have also identified considerable spatial variability in the GPS field, seismicity, crust and mantle structure, magnitude and timing of exhumation, erosion, and strain. While much has been learned and many details revealed, significant questions about the Himalaya and Tibet remain and we lack integrated 4D models that explain observed complexity. The time is right for a community initiative to systematically integrate the breadth of data available to test and refine geodynamic models to illuminate the structure and 4-D evolution of the India-Asia collision at scales that account for both first order observations and lateral heterogeneity, link deep earth and surface processes, and address the geohazards associated with the collisional zone and surrounding areas. Any such effort requires community consensus on science goals, setting priorities regarding what's needed to make significant progress, and open access data. An effort of this scale needs to address the societal impacts of hazards associated with the India-Asia collisional system and engage international collaborations across the region. The April 2015 Mw 7.8 Gorkha, Nepal earthquake serves as the most recent reminder that the Himalaya-Tibet system is capable of producing large magnitude events, impacting lives, livelihoods, and the built environment. The 1950 Mw 8.6 Assam and 2008 Mw 7.9 Wenchuan

  18. Selected constants oxidation-reduction potentials of inorganic substances in aqueous solution

    CERN Document Server

    Charlot, G; Marchon, M J C

    2013-01-01

    Selected Constants: Oxidation-reduction Potentials of Inorganic Substances in Aqueous Solution presents tables that will aid chemists in finding the best or most probable value of the normal or formal oxidation-reduction potential of oxidation-reduction systems. The book first presents numerical calculations that show the degree of oxidation and real oxidation-reduction systems, including the value of the potential, temperature, nature and composition of the medium, and the method of determination used. The text then takes a look at the choice of data, as well as intensity/potential curves an

  19. Selective androgen receptor modulators in drug discovery: medicinal chemistry and therapeutic potential.

    Science.gov (United States)

    Cadilla, Rodolfo; Turnbull, Philip

    2006-01-01

    Modulation of the androgen receptor has the potential to be an effective treatment for hypogonadism, andropause, and associated conditions such as sarcopenia, osteoporosis, benign prostatic hyperplasia, and sexual dysfunction. Side effects associated with classical anabolic steroid treatments have driven the quest for drugs that demonstrate improved therapeutic profiles. Novel, non-steroidal compounds that show tissue selective activity and improved pharmacokinetic properties have been developed. This review provides an overview of current advances in the development of selective androgen receptor modulators (SARMs).

  20. Accuracy assessment of gridded precipitation datasets in the Himalayas

    Science.gov (United States)

    Khan, A.

    2015-12-01

    Accurate precipitation data are vital for hydro-climatic modelling and water resources assessments. Based on mass balance calculations and Turc-Budyko analysis, this study investigates the accuracy of twelve widely used precipitation gridded datasets for sub-basins in the Upper Indus Basin (UIB) in the Himalayas-Karakoram-Hindukush (HKH) region. These datasets are: 1) Global Precipitation Climatology Project (GPCP), 2) Climate Prediction Centre (CPC) Merged Analysis of Precipitation (CMAP), 3) NCEP / NCAR, 4) Global Precipitation Climatology Centre (GPCC), 5) Climatic Research Unit (CRU), 6) Asian Precipitation Highly Resolved Observational Data Integration Towards Evaluation of Water Resources (APHRODITE), 7) Tropical Rainfall Measuring Mission (TRMM), 8) European Reanalysis (ERA) interim data, 9) PRINCETON, 10) European Reanalysis-40 (ERA-40), 11) Willmott and Matsuura, and 12) WATCH Forcing Data based on ERA interim (WFDEI). Precipitation accuracy and consistency was assessed by physical mass balance involving sum of annual measured flow, estimated actual evapotranspiration (average of 4 datasets), estimated glacier mass balance melt contribution (average of 4 datasets), and ground water recharge (average of 3 datasets), during 1999-2010. Mass balance assessment was complemented by Turc-Budyko non-dimensional analysis, where annual precipitation, measured flow and potential evapotranspiration (average of 5 datasets) data were used for the same period. Both analyses suggest that all tested precipitation datasets significantly underestimate precipitation in the Karakoram sub-basins. For the Hindukush and Himalayan sub-basins most datasets underestimate precipitation, except ERA-interim and ERA-40. The analysis indicates that for this large region with complicated terrain features and stark spatial precipitation gradients the reanalysis datasets have better consistency with flow measurements than datasets derived from records of only sparsely distributed climatic

  1. Nature and Timing of Quaternary glaciation in the Himalaya: Review and Speculation

    Science.gov (United States)

    Owen, L. A.

    2012-12-01

    Reconstructions of the extent and defining the timing of Quaternary glaciation across the Himalaya is an important step towards understanding the nature of long-term (centennial-millennial scale) climate-glacier dynamics in the high mountains of Central Asia. Recent efforts, aided by extensive programs of mapping and numerical dating, are beginning to more accurately define the extent and timing of Quaternary glaciation throughout the Himalayan-Tibetan orogen. The picture that is emerging is one of complex variation in the timing and extent of glaciation within and between regions. This variation is likely controlled by regional differences in the role of the major climatic systems that influence the region over time and topographic factors. A transect across the western end of the Himalayan-Tibetan orogen, including detailed studies in the Lahul Himalaya, Zanskar, Ladakh, Hunza and the Pamir, illustrates this complexity. This transect has the potential, when examined in more detail using newly developing numerical dating, and geomorphic and sedimentologic methods, to derive high-resolution records of glaciation that will help in understanding the complex relationship between climate-glacier dynamics and topography.

  2. Selective attention and the auditory vertex potential. 1: Effects of stimulus delivery rate

    Science.gov (United States)

    Schwent, V. L.; Hillyard, S. A.; Galambos, R.

    1975-01-01

    Enhancement of the auditory vertex potentials with selective attention to dichotically presented tone pips was found to be critically sensitive to the range of inter-stimulus intervals in use. Only at the shortest intervals was a clear-cut enhancement of the latency component to stimuli observed for the attended ear.

  3. betaFIT: A computer program to fit pointwise potentials to selected analytic functions

    Science.gov (United States)

    Le Roy, Robert J.; Pashov, Asen

    2017-01-01

    This paper describes program betaFIT, which performs least-squares fits of sets of one-dimensional (or radial) potential function values to four different types of sophisticated analytic potential energy functional forms. These families of potential energy functions are: the Expanded Morse Oscillator (EMO) potential [J Mol Spectrosc 1999;194:197], the Morse/Long-Range (MLR) potential [Mol Phys 2007;105:663], the Double Exponential/Long-Range (DELR) potential [J Chem Phys 2003;119:7398], and the "Generalized Potential Energy Function (GPEF)" form introduced by Šurkus et al. [Chem Phys Lett 1984;105:291], which includes a wide variety of polynomial potentials, such as the Dunham [Phys Rev 1932;41:713], Simons-Parr-Finlan [J Chem Phys 1973;59:3229], and Ogilvie-Tipping [Proc R Soc A 1991;378:287] polynomials, as special cases. This code will be useful for providing the realistic sets of potential function shape parameters that are required to initiate direct fits of selected analytic potential functions to experimental data, and for providing better analytical representations of sets of ab initio results.

  4. Morphometric analysis of Suketi river basin, Himachal Himalaya, India

    Indian Academy of Sciences (India)

    Anil M Pophare; Umesh S Balpande

    2014-10-01

    Suketi river basin is located in the Mandi district of Himachal Pradesh, India. It encompasses a central inter-montane valley and surrounding mountainous terrain in the Lower Himachal Himalaya. Morphometric analysis of the Suketi river basin was carried out to study its drainage characteristics and overall groundwater resource potential. The entire Suketi river basin has been divided into five sub-basins based on the catchment areas of Suketi trunk stream and its major tributaries. Quantitative assessment of each sub-basin was carried out for its linear, areal, and relief aspects. The analysis reveals that the drainage network of the entire Suketi river basin constitutes a 7th order basin. Out of five sub-basins, Kansa khad sub-basin (KKSB), Gangli khad sub-basin (GKSB) and Ratti khad sub-basin (RKSB) are 5th order subbasins. The Dadour khad sub-basin (DKSB) is 6th order sub-basin, while Suketi trunk stream sub-basin (STSSB) is a 7th order sub-basin. The entire drainage basin area reflects late youth to early mature stage of development of the fluvial geomorphic cycle, which is dominated by rain and snow fed lower order streams. It has low stream frequency (Fs) and moderate drainage density (Dd) of 2.69 km/km2. Bifurcation ratios (Rb) of various stream orders indicate that streams up to 3rd order are surging through highly dissected mountainous terrain, which facilitates high overland flow and less recharge into the subsurface resulting in low groundwater potential in the zones of 1st, 2nd, and 3rd order streams of the Suketi river basin. The circulatory ratio (Rc) of 0.65 and elongation ratio (Re) of 0.80 show elongated nature of the Suketi river basin, while infiltration number (If) of 10.66 indicates dominance of relief features and low groundwater potential in the high altitude mountainous terrain. The asymmetry factor (Af) of Suketi river basin indicates that the palaeo-tectonic tilting, at drainage basin scale, was towards the downstream right side of the

  5. Considering Future Potential Regarding Structural Diversity in Selection of Forest Reserves.

    Science.gov (United States)

    Lundström, Johanna; Öhman, Karin; Rönnqvist, Mikael; Gustafsson, Lena

    2016-01-01

    A rich structural diversity in forests promotes biodiversity. Forests are dynamic and therefore it is crucial to consider future structural potential when selecting reserves, to make robust conservation decisions. We analyzed forests in boreal Sweden based on 17,599 National Forest Inventory (NFI) plots with the main aim to understand how effectiveness of reserves depends on the time dimension in the selection process, specifically by considering future structural diversity. In the study both the economic value and future values of 15 structural variables were simulated during a 100 year period. To get a net present structural value (NPSV), a single value covering both current and future values, we used four discounting alternatives: (1) only considering present values, (2) giving equal importance to values in each of the 100 years within the planning horizon, (3) applying an annual discount rate considering the risk that values could be lost, and (4) only considering the values in year 100. The four alternatives were evaluated in a reserve selection model under budget-constrained and area-constrained selections. When selecting young forests higher structural richness could be reached at a quarter of the cost over almost twice the area in a budget-constrained selection compared to an area-constrained selection. Our results point to the importance of considering future structural diversity in the selection of forest reserves and not as is done currently to base the selection on existing values. Targeting future values increases structural diversity and implies a relatively lower cost. Further, our results show that a re-orientation from old to young forests would imply savings while offering a more extensive reserve network with high structural qualities in the future. However, caution must be raised against a drastic reorientation of the current old-forest strategy since remnants of ancient forests will need to be prioritized due to their role for disturbance

  6. Selection of measures for a potential with two maxima at the zero temperature limit

    CERN Document Server

    Baraviera, Alexandre T; Lopes, Artur O

    2010-01-01

    For the subshift of finite type $\\S=\\{0,1,2\\}^{\\N}$ we study the convergence at temperature zero of the Gibbs measure associated to a non-locally constant H\\"older potential which admits only two maximizing measures. These measures are Dirac measures at two different fixed points. The potential is flattest at one of these two fixed points. The question we are interested is: which of these probabilities the invariant Gibbs state will select when temperature goes to zero? We prove that on the one hand the Gibbs measure converges, and at the other hand it does not necessarily converge to the measures where the potential is the flattest. We consider a family of potentials of the above form; for some of them there is the selection of a convex combination of the two Dirac measures, and for others there is a selection of the Dirac measure associated to the flattest point. In the first case this is contrary to what was expected if we consider the analogous problem in Aubry-Mather theory by N. Anantharaman, R. Iturria...

  7. Dopamine D(3) receptor antagonists: The quest for a potentially selective PET ligand. Part two: Lead optimization.

    Science.gov (United States)

    Micheli, Fabrizio; Holmes, Ian; Arista, Luca; Bonanomi, Giorgio; Braggio, Simone; Cardullo, Francesca; Di Fabio, Romano; Donati, Daniele; Gentile, Gabriella; Hamprecht, Dieter; Terreni, Silvia; Heidbreder, Christian; Savoia, Chiara; Griffante, Cristiana; Worby, Angela

    2009-08-01

    The lead optimization process to identify new selective dopamine D(3) receptor antagonists is reported. DMPK parameters and binding data suggest that selective D(3) receptor antagonists as potential PET ligands might have been identified.

  8. Environmental change and challenge in the Himalaya. A historical perspective

    Directory of Open Access Journals (Sweden)

    Ives, Jack D.

    2012-05-01

    Full Text Available This overview, or retrospective, has two objectives. The first is to demonstrate how the principles of ‘mountain geoecology’ were applied in an attempt to counteract the political and socio-economic impacts of a major and misguided environmental orthodoxy-the Theory of Himalayan Environmental Degradation (henceforth to be referred to as the ‘Theory’. The second is to explore the difficulties of transferring the results of on-going scholarly mountain research into the public and political decision-making process. In this sense the paper should be regarded as a case study of the potentially serious effects of exaggerated and emotionally based responses to orthodoxies founded on assumptions and latter-day myths. A third objective, reserved for the companion paper in this issue, outlines the origins of mountain geoecology and explores how academic research influenced the inclusion of high level concern for mountain problems within AGENDA 21, one of the principal results of the 1992 UN Conference on Environment and Development (popularly known as the Rio Earth Summit and declaration of 2002 as the International Year of Mountains. The original environmental orthodoxy (the Theory has been eclipsed since the turn of the Millennium by a new populist alarm proposing that the current climate warming will cause all the Himalayan glaciers to disappear in the near future. From this it would follow that, as the glacier melt progresses, numerous large glacial lakes, forming as a consequence, would burst and the ensuing floods would annihilate many millions of people. Eventually, as the glaciers disappeared vital rivers, such as the Ganges and Brahmaputra, would wither to seasonal streams heralding further massive loss of life due to desertification and starvation. This current environmental alarm could be regarded as a present day parallel to the original Theory and will be examined in the final section of the paper. Between 1970 and about 1985 it was

  9. The coalbed methane production potential method for optimization of wells location selection

    Institute of Scientific and Technical Information of China (English)

    Feng-Ke DOU; Yong-Shang KANG; Shao-Feng QIN; De-Lei MAO; Jun HAN

    2013-01-01

    A gas production potential method for optimization of gas wellsite locations selection is proposed in terms of the coalbed gas resources volume and the recoverability.The method uses the actual data about reservoirs in a coalbed gas field in central China to optimize wellsite locations in the studied area in combination with the dynamic data about actual production in the coalbed gas field,selects a favorable subarea for gas wells deployment.The method is established based on the basic properties of coal reservoirs,in combination with the coalbed thickness and the gas content to make an analysis of the gas storage potential of a coal reservoir,as well as resources volume and the permeability of a coal reservoir.This method can be popularized for optimization of wellsite locations in other methane gas development areas or blocks.

  10. A Potential Waste to be Selected as Media for Metal and Nutrient Removal

    Science.gov (United States)

    Zayadi, N.; Othman, N.; Hamdan, R.

    2016-07-01

    This study describes the potential of application of cassava peel, banana peel, coconut shell, and coconut coir to be selected as metal removal while limestone and steel slag for nutrient removal. The media were characterized by X-Ray Fluorescence (XRF), Fourier Transform Infrared (FTIR), Field Emission Scanning Electron Microscopy-Energy Dispersive X-Ray (FESEM-EDX), and X-Ray Powder Diffraction (XRD). The results of XRF analysis medias show the present of calcium oxide, CaO which confirm the high efficiency in adsorbing metal ions and nutrient which is in agreement with the result of XRD. The characteristics of medias by FTIR analysis also confirmed the involvement of alcohol, carboxylic, alkanes, amines and ethers which play important role to reduce ions while FESEM-EDX indicates the porous structures of study medias. The characterization analysis highlight that cassava peel and steel slag were selected as a potential media in this study.

  11. Northward genetic penetration across the Himalayas viewed from Sherpa people.

    Science.gov (United States)

    Kang, Longli; Wang, Chuan-Chao; Chen, Feng; Yao, Dali; Jin, Li; Li, Hui

    2016-01-01

    The Himalayas have been suggested as a natural barrier for human migrations, especially the northward dispersals from the Indian Subcontinent to Tibetan Plateau. However, although the majority of Sherpa have a Tibeto-Burman origin, considerable genetic components from Indian Subcontinent have been observed in Sherpa people living in Tibet. The western Y chromosomal haplogroups R1a1a-M17, J-M304, and F*-M89 comprise almost 17% of Sherpa paternal gene pool. In the maternal side, M5c2, M21d, and U from the west also count up to 8% of Sherpa people. Those lineages with South Asian origin indicate that the Himalayas have been permeable to bidirectional gene flow.

  12. Brief Communication: Contending estimates of early 21st century glacier mass balance over the Pamir-Karakoram-Himalaya

    Science.gov (United States)

    Kääb, A.; Nuth, C.; Treichler, D.; Berthier, E.

    2014-11-01

    We present glacier thickness changes over the entire Pamir-Karakoram-Himalaya arc based on ICESat satellite altimetry data for 2003-2008. The strongest thinning (mass change reaches -22 ± 3 Gt yr-1, about 10% of the current glacier contribution to sea-level rise. For selected catchments over the study area we estimate glacier imbalance contributions to river runoff from a few percent to far over 10%. We highlight the importance of C-band penetration for studies based on the SRTM elevation model. To the very east and west of our study area, this penetration seems to be of larger magnitude and variability than previously assumed.

  13. [Potential-dependent Cation Selective Ion Channels Formed by Peroxiredoxin 6 in the Lipid Bilayer].

    Science.gov (United States)

    Grigoriev, P A; Sharapov, M G; Novoselov, V I

    2015-01-01

    The antioxidant enzyme peroxiredoxin 6 forms cation selective ion cluster-type channels in the lipid bilayer. Channel clustering as oligomeric structure consists of three or more subunits--channels with conductance of about 350 pS in the 200 mM KCl. Mean dwell time of the channel's open states decreases with increasing membrane voltage. A possible molecular mechanism of the observed potential-dependent inactivation of the channel cluster is discussed.

  14. Evoked potential correlates of selective attention with multi-channel auditory inputs

    Science.gov (United States)

    Schwent, V. L.; Hillyard, S. A.

    1975-01-01

    Ten subjects were presented with random, rapid sequences of four auditory tones which were separated in pitch and apparent spatial position. The N1 component of the auditory vertex evoked potential (EP) measured relative to a baseline was observed to increase with attention. It was concluded that the N1 enhancement reflects a finely tuned selective attention to one stimulus channel among several concurrent, competing channels. This EP enhancement probably increases with increased information load on the subject.

  15. ORIGINAL ARTICLE: In-vitro Antioxidant Potential of a Herbal Preparation Containing Four Selected Medicinal Plants

    OpenAIRE

    2012-01-01

    Background: The therapeutic effects of several plants used in traditional medicine, are usually attributed to their antioxidant properties. Aim and objective: To evaluate the in-vitro antioxidant potential of herbal preparation a combination of four selected medicinal plants (HP-4) using different experimental models.Material and Methods: Polyphenols, flavonoids and flavonols concentrations and antioxidant activity of herbal preparation (HP-4)as compared to butylated hydroxyl toluene (BHT) an...

  16. Selecting for creativity and innovation potential: implications for practice in healthcare education.

    Science.gov (United States)

    Patterson, Fiona; Zibarras, Lara Dawn

    2017-05-01

    The ability to innovate is an important requirement in many organisations. Despite this pressing need, few selection systems in healthcare focus on identifying the potential for creativity and innovation and so this area has been vastly under-researched. As a first step towards understanding how we might select for creativity and innovation, this paper explores the use of a trait-based measure of creativity and innovation potential, and evaluates its efficacy for use in selection for healthcare education. This study uses a sample of 188 postgraduate physicians applying for education and training in UK General Practice. Participants completed two questionnaires (a trait-based measure of creativity and innovation, and a measure of the Big Five personality dimensions) and were also rated by assessors on creative problem solving measured during a selection centre. In exploring the construct validity of the trait-based measure of creativity and innovation, our research clarifies the associations between personality, and creativity and innovation. In particular, our study highlights the importance of motivation in the creativity and innovation process. Results also suggest that Openness to Experience is positively related to creativity and innovation whereas some aspects of Conscientiousness are negatively associated with creativity and innovation. Results broadly support the utility of using a trait-based measure of creativity and innovation in healthcare selection processes, although practically this may be best delivered as part of an interview process, rather than as a screening tool. Findings are discussed in relation to broader implications for placing more priority on creativity and innovation as selection criteria within healthcare education and training in future.

  17. Assessing the potential for post-copulatory sexual selection in elasmobranchs.

    Science.gov (United States)

    Fitzpatrick, J L; Kempster, R M; Daly-Engel, T S; Collin, S P; Evans, J P

    2012-04-01

    This review highlights the potential role that post-copulatory sexual selection plays in elasmobranch reproductive systems and the utility of this group to further understanding of evolutionary responses to the post-copulatory processes of sperm competition and cryptic female choice. The growing genetic evidence for female multiple mating (polyandry) in elasmobranchs is summarized. While polyandry appears to be common in this group, rates of multiple paternity are highly variable between species suggesting that there is large variance in the strength of post-copulatory sexual selection among elasmobranchs. Possible adaptations of traits important for post-copulatory sexual selection are then considered. Particular emphasis is devoted to explore the potential for sperm competition and cryptic female choice to influence the evolution of testes size, sperm morphology, genital morphology and sperm storage organs. Finally, it is argued that future work should take advantage of the wealth of information on these reproductive traits already available in elasmobranchs to gain a better understanding of how post-copulatory sexual selection operates in this group.

  18. Lateral variation of seismic attenuation in Sikkim Himalaya

    Science.gov (United States)

    Thirunavukarasu, Ajaay; Kumar, Ajay; Mitra, Supriyo

    2017-01-01

    We use data from local earthquakes (mb ≥ 3.0) recorded by the Sikkim broad-band seismograph network to study the frequency-dependent attenuation of the crust and uppermost mantle. These events have been relocated using body wave phase data from local and regional seismograms. The decay of coda amplitudes at a range of central frequencies (1 to 12 Hz) has been measured for 74 earthquake-receiver pairs. These measurements are combined to estimate the frequency-dependent coda Q of the form Q( f) = Q0 f η. The estimated Q0 values range from 80 to 200, with an average of 123 ± 29; and η ranges from 0.92 to 1.04, with an average of 0.98 ± 0.04. To study the lateral variation of Q0 and η, we regionalized the measured Q values by combining all the earthquake-receiver path measurements through a back projection algorithm. We consider a single back-scatter model for the coda waves with elliptical sampling and parametrize the sampled area using 0.2° square grids. A nine-point spatial smoothening (similar to spatial Gaussian filter) is applied to stabilize the inversion. This is done at every frequency to observe the spatial variation of Q( f) and subsequently combined to obtain η variations. Results of our study reveal that the Sikkim Himalaya is characterized by low Q0 (80-100) compared to the foreland basin to its south (150-200) and the Nepal Himalaya to its west (140-160). The low Q and high η in Sikkim Himalaya is attributed to extrinsic scattering attenuation from structural heterogeneity and active faults within the crust, and intrinsic attenuation due to anelasticity in the hotter lithosphere beneath the actively deforming mountain belt. Similar low Q and high η values had also been observed in northwest and Garhwal-Kumaun Himalaya.

  19. Treeline dynamics with climate change at the central Nepal Himalaya

    OpenAIRE

    2014-01-01

    Treeline shifting in tandem with climate change has widely been reported from various parts of the world. In Nepal, several impacts of climate change on the physical environment have been observed, but study on the biological impacts is lacking. This dendrochronological study was carried out at the treeline in the high mountain slope of Kalchuman Lake (3750–4003 m a.s.l.) area of Manaslu Conservation Area in the central Nepal Himalaya to explore the impact of climate change ...

  20. New chromosome reports in Lamiaceae of Kashmir (Northwest Himalaya), India.

    Science.gov (United States)

    Malik, Reyaz Ahmad; Gupta, Raghbir Chand; Singh, Vijay; Bala, Santosh; Kumari, Santosh

    2017-03-01

    Meiotic studies and chromosome data are imperative in order to have an overall germplasm evaluation of a taxon. In the present effort, the meiotic study is carried out in 48 populations belonging to 26 species of Lamiaceae collected from their natural habitats in Kashmir Himalaya, which forms an important part of Northwest Himalaya. Chromosome counts in the five species viz. Dracocephalum nutans (2n = 10), Lycopus europaeus (2n = 22), Marrubium vulgare (2n = 54), Nepeta nervosa (2n = 18) and Salvia sclarea (2n = 22) are first time reported from India. Besides, 17 species are cytologically evaluated for the first time from the study area-Kashmir Himalaya. In Marrubium vulgare, hexaploid cytotype (2n = 6 × =54) is reported for the first time. Also, diploid and tetraploid cytomorphovariants are observed in Calamintha vulgaris (2n = 20, 40), Elsholtzia ciliata (2n = 16, 32) and Mentha longifolia (2n = 20, 40). Various meiotic abnormalities like chromatin stickiness, cytomixis, nonsynchronous disjunction, laggards, chromatin bridges, etc. leading to pollen abnormalities have been documented for the first time in some species. The worldwide status of chromosome number data in each genus is presented.

  1. Tunnelling through weak and fragile rocks of Himalayas

    Institute of Scientific and Technical Information of China (English)

    Goel R.K.

    2014-01-01

    A considerable amount of tunnelling has been going on in India for various projects such as hydroelectric power, irrigation, roads and railways. Most of these projects are located in Himalayas, far away from the urban areas. Tunnelling through weak and jointed rock masses such as the one in the Himalayas is a challenging task for the planners, designers, engineers and geologists because of high overburden, thickly vegetated surface, weak, poor and fragile rocks and highly varying geology with the presence of numerous small and big shear zones, faults, etc. Due to these reasons, various tunnelling problems have been faced in the past and are still being encountered. Failures and the problems may be regarded as challenges and opportunities for generating new knowledge base and thereby increasing self-reliance in tunnelling. The experiences of Himalayan tunnelling through weak and fragile rocks covering varying and mixed geology, understanding on tunnelling in squeezing ground conditions and applicability of TBM in Himalayas are presented. It has also been highlighted that the probe holes planning, drilling and mon-itoring shall be followed seriously to reduce the geological surprises.

  2. Body Wave Crustal Attenuation Characteristics in the Garhwal Himalaya, India

    Science.gov (United States)

    Negi, Sanjay S.; Paul, Ajay; Joshi, Anand; Kamal

    2015-06-01

    We estimate frequency-dependent attenuation of P and S waves in Garhwal Himalaya using the extended coda normalization method for the central frequencies 1.5, 2, 3, 4, 6, 8, 10, 12, and 16 Hz, with earthquake hypocentral distance ranging from 27 to 200 km. Forty well-located local earthquake waveforms were used to study the seismic attenuation characteristics of the Garhwal Himalaya, India, as recorded by eight stations operated by Wadia Institute of Himalayan Geology, Dehradun, India, from 2007 to 2012. We find frequency-dependent P and S wave quality factors as defined by the relations Q P = 56 ± 8 f 0.91±0.002 and Q S = 151 ± 8 f 0.84±0.002 by fitting a power-law frequency dependence model for the estimated values over the whole region. Both the Q P and Q S values indicate strong attenuation in the crust of Garhwal Himalaya. The ratio of Q S/ Q P > 1 obtained for the entire analyzed frequency range suggests that the scattering loss is due to a random and high degree of heterogeneities in the earth medium, playing an important role in seismic wave attenuation in the Himalayan crust.

  3. Projected hydrologic changes in monsoon-dominated Himalaya Mountain basins with changing climate and deforestation

    Science.gov (United States)

    Neupane, Ram P.; White, Joseph D.; Alexander, Sara E.

    2015-06-01

    In mountain headwaters, climate and land use changes affect short and long term site water budgets with resultant impacts on landslide risk, hydropower generation, and sustainable agriculture. To project hydrologic change associated with climate and land use changes in the Himalaya Mountains, we used the Soil and Water Assessment Tool (SWAT) calibrated for the Tamor and Seti River basins located at eastern and western margins of Nepal. Future climate change was modeled using averaged temperature and precipitation for 2080 derived from Special Report on Emission Scenarios (SRES) (B1, A1B and A2) of 16 global circulation models (GCMs). Land use change was modeled spatially and included expansion of (1) agricultural land, (2) grassland, and (3) human settlement area that were produced by considering existing land use with projected changes associated with viability of elevation and slope characteristics of the basins capable of supporting different land use type. From these simulations, higher annual stream discharge was found for all GCM-derived scenarios compared to a baseline simulation with maximum increases of 13 and 8% in SRES-A2 and SRES-A1B for the Tamor and Seti basins, respectively. On seasonal basis, we assessed higher precipitation during monsoon season in all scenarios that corresponded with higher stream discharge of 72 and 68% for Tamor and Seti basins, respectively. This effect appears to be geographically important with higher influence in the eastern Tamor basin potentially due to longer and stronger monsoonal period of that region. However, we projected minimal changes in stream discharge for the land use scenarios potentially due to higher water transmission to groundwater reservoirs associated with fractures of the Himalaya Mountains rather than changes in surface runoff. However, when combined the effects of climate and land use changes, discharge was moderately increased indicating counteracting mechanisms of hydrologic yield in these mountains

  4. Analysis of soil moisture variation by forest cover structure in lower western Himalayas, India

    Institute of Scientific and Technical Information of China (English)

    J.v.Tyagi; Nuzhat Qazi; S.P.Rai; M.P.Singh

    2013-01-01

    Soil moisture affects various hydrological processes,including evapotranspiration,infiltration,and runoff.Forested areas in the lower western Himalaya in India constitute the headwater catchments for many hill streams and have experienced degradation in forest cover due to grazing,deforestation and other human activities.This change in forest cover is likely to alter the soil moisture regime and,consequently,flow regimes in streams.The effect of change in forest cover on soil moisture regimes of this dry region has not been studied through long term field observations.We monitored soil matric potentials in two small watersheds in the lower western Himalaya of India.The watersheds consisted of homogeneous land covers of moderately dense oak forest and moderately degraded mixed oak forest.Observations were recorded at three sites at three depths in each watershed at fortnightly intervals for a period of three years.The soil moisture contents derived from soil potential measurements were analyzed to understand the spatial,temporal and profile variations under the two structures of forest cover.The analysis revealed large variations in soil moisture storage at different sites and depths and also during different seasons in each watershed.Mean soil moisture storage during monsoon,winter and summer seasons was higher under dense forest than under degraded forest.Highest soil moisture content occurred at shallow soil profiles,decreasing with depth in both watersheds.A high positive correlation was found between tree density and soil moisture content.Mean soil moisture content over the entire study period was higher under dense forest than under degraded forest.This indicated a potential for soil water storage under well managed oak forest.Because soil water storage is vital for sustenance of low flows,attention is needed on the management of oak forests in the Himalayan region.

  5. Towards an improved inventory of Glacial Lake Outburst Floods in the Himalayas

    Science.gov (United States)

    Veh, Georg; Walz, Ariane; Korup, Oliver; Roessner, Sigrid

    2016-04-01

    The retreat of glaciers in the Himalayas and the associated release of meltwater have prompted the formation and growth of thousands of glacial lakes in the last decades. More than 2,200 of these lakes have developed in unconsolidated moraine material. These lakes can drain in a single event, producing potentially destructive glacial lake outburst floods (GLOFs). Only 44 GLOFs in the Himalayas have been documented in more detail since the 1930s, and evidence for a change, let alone an increase, in the frequency of these flood events remains elusive. The rare occurrence of GLOFs is counterintuitive to our hypothesis that an increasing amount of glacial lakes has to be consistent with a rising amount of outburst floods. Censoring bias affects the GLOF record, such that mostly larger floods with commensurate impact have been registered. Existing glacial lake inventories are also of limited help for the identification of GLOFs, as they were created in irregular time steps using different methodological approach and covering different regional extents. We discuss the key requirements for generating a more continuous, close to yearly time series of glacial lake evolution for the Himalayan mountain range using remote sensing data. To this end, we use sudden changes in glacial lake areas as the key diagnostic of dam breaks and outburst floods, employing the full archive of cloud-free Landsat data (L5, L7 and L8) from 1988 to 2015. SRTM and ALOS World 3D topographic data further improve the automatic detection of glacial lakes in an alpine landscape that is often difficult to access otherwise. Our workflow comprises expert-based classification of water bodies using thresholds and masks from different spectral indices and band ratios. A first evaluation of our mapping approach suggests that GLOFs reported during the study period could be tracked independently by a significant reduction of lake size between two subsequent Landsat scenes. This finding supports the feasibility

  6. FOREST ECOSYSTEM DYNAMICS ASSESSMENT AND PREDICTIVE MODELLING IN EASTERN HIMALAYA

    Directory of Open Access Journals (Sweden)

    S. P. S. Kushwaha

    2012-09-01

    Full Text Available This study focused on the forest ecosystem dynamics assessment and predictive modelling deforestation and forest cover prediction in a part of north-eastern India i.e. forest areas along West Bengal, Bhutan, Arunachal Pradesh and Assam border in Eastern Himalaya using temporal satellite imagery of 1975, 1990 and 2009 and predicted forest cover for the period 2028 using Cellular Automata Markov Modedel (CAMM. The exercise highlighted large-scale deforestation in the study area during 1975–1990 as well as 1990–2009 forest cover vectors. A net loss of 2,334.28 km2 forest cover was noticed between 1975 and 2009, and with current rate of deforestation, a forest area of 4,563.34 km2 will be lost by 2028. The annual rate of deforestation worked out to be 0.35 and 0.78% during 1975–1990 and 1990–2009 respectively. Bamboo forest increased by 24.98% between 1975 and 2009 due to opening up of the forests. Forests in Kokrajhar, Barpeta, Darrang, Sonitpur, and Dhemaji districts in Assam were noticed to be worst-affected while Lower Subansiri, West and East Siang, Dibang Valley, Lohit and Changlang in Arunachal Pradesh were severely affected. Among different forest types, the maximum loss was seen in case of sal forest (37.97% between 1975 and 2009 and is expected to deplete further to 60.39% by 2028. The tropical moist deciduous forest was the next category, which decreased from 5,208.11 km2 to 3,447.28 (33.81% during same period with further chances of depletion to 2,288.81 km2 (56.05% by 2028. It noted progressive loss of forests in the study area between 1975 and 2009 through 1990 and predicted that, unless checked, the area is in for further depletion of the invaluable climax forests in the region, especially sal and moist deciduous forests. The exercise demonstrated high potential of remote sensing and geographic information system for forest ecosystem dynamics assessment and the efficacy of CAMM to predict the forest cover change.

  7. Geomorphological evidences of post-LGM glacial advancements in the Himalaya: A study from Chorabari Glacier, Garhwal Himalaya, India

    Indian Academy of Sciences (India)

    Manish Mehta; Zahid Majeed; D P Dobhal; Pradeep Srivastava

    2012-02-01

    Field geomorphology and remote sensing data, supported by Optical Stimulated Luminescence (OSL) dating from the Mandakini river valley of the Garhwal Himalaya enabled identification of four major glacial events; Rambara Glacial Stage (RGS) (13 ± 2 ka), Ghindurpani Glacial Stage (GhGS) (9 ± 1 ka), Garuriya Glacial Stage (GGS) (7 ± 1 ka) and Kedarnath Glacial Stage (KGS) (5 ± 1 ka). RGS was the most extensive glaciation extending for ∼6 km down the valley from the present day snout and lowered to an altitude of 2800 m asl at Rambara covering around ∼31 km2 area of the Mandakini river valley. Compared to this, the other three glaciations (viz., GhGS, GGS and KGS) were of lower magnitudes terminating around ∼3000, ∼3300 and ∼3500 m asl, respectively. It was also observed that the mean equilibrium line altitude (ELA) during RGS was lowered to 4747 m asl compared to the present level of 5120 m asl. This implies an ELA depression of ∼373 m during the RGS which would correspond to a lowering of ∼2°C summer temperature during the RGS. The results are comparable to that of the adjacent western and central Himalaya implying a common forcing factor that we attribute to the insolation-driven monsoon precipitation in the western and central Himalaya.

  8. Potential assessment of genome-wide association study and genomic selection in Japanese pear Pyrus pyrifolia.

    Science.gov (United States)

    Iwata, Hiroyoshi; Hayashi, Takeshi; Terakami, Shingo; Takada, Norio; Sawamura, Yutaka; Yamamoto, Toshiya

    2013-03-01

    Although the potential of marker-assisted selection (MAS) in fruit tree breeding has been reported, bi-parental QTL mapping before MAS has hindered the introduction of MAS to fruit tree breeding programs. Genome-wide association studies (GWAS) are an alternative to bi-parental QTL mapping in long-lived perennials. Selection based on genomic predictions of breeding values (genomic selection: GS) is another alternative for MAS. This study examined the potential of GWAS and GS in pear breeding with 76 Japanese pear cultivars to detect significant associations of 162 markers with nine agronomic traits. We applied multilocus Bayesian models accounting for ordinal categorical phenotypes for GWAS and GS model training. Significant associations were detected at harvest time, black spot resistance and the number of spurs and two of the associations were closely linked to known loci. Genome-wide predictions for GS were accurate at the highest level (0.75) in harvest time, at medium levels (0.38-0.61) in resistance to black spot, firmness of flesh, fruit shape in longitudinal section, fruit size, acid content and number of spurs and at low levels (pear.

  9. Direction-selective circuitry in rat retina develops independently of GABAergic, cholinergic and action potential activity.

    Directory of Open Access Journals (Sweden)

    Le Sun

    Full Text Available The ON-OFF direction selective ganglion cells (DSGCs in the mammalian retina code image motion by responding much more strongly to movement in one direction. They do so by receiving inhibitory inputs selectively from a particular sector of processes of the overlapping starburst amacrine cells, a type of retinal interneuron. The mechanisms of establishment and regulation of this selective connection are unknown. Here, we report that in the rat retina, the morphology, physiology of the ON-OFF DSGCs and the circuitry for coding motion directions develop normally with pharmacological blockade of GABAergic, cholinergic activity and/or action potentials for over two weeks from birth. With recent results demonstrating light independent formation of the retinal DS circuitry, our results strongly suggest the formation of the circuitry, i.e., the connections between the second and third order neurons in the visual system, can be genetically programmed, although emergence of direction selectivity in the visual cortex appears to require visual experience.

  10. Acoustic Noise Alters Selective Attention Processes as Indicated by Direct Current (DC Brain Potential Changes

    Directory of Open Access Journals (Sweden)

    Karin Trimmel

    2014-09-01

    Full Text Available Acoustic environmental noise, even of low to moderate intensity, is known to adversely affect information processing in animals and humans via attention mechanisms. In particular, facilitation and inhibition of information processing are basic functions of selective attention. Such mechanisms can be investigated by analyzing brain potentials under conditions of externally directed attention (intake of environmental information versus internally directed attention (rejection of environmental stimuli and focusing on memory/planning processes. This study investigated brain direct current (DC potential shifts—which are discussed to represent different states of cortical activation—of tasks that require intake and rejection of environmental information under noise. It was hypothesized that without background noise rejection tasks would show more positive DC potential changes compared to intake tasks and that under noise both kinds of tasks would show positive DC shifts as an expression of cortical inhibition caused by noise. DC potential shifts during intake and rejection tasks were analyzed at 16 standard locations in 45 persons during irrelevant speech or white noise vs. control condition. Without noise, rejection tasks were associated with more positive DC potential changes compared to intake tasks. During background noise, however, this difference disappeared and both kinds of tasks led to positive DC shifts. Results suggest—besides some limitations—that noise modulates selective attention mechanisms by switching to an environmental information processing and noise rejection mode, which could represent a suggested “attention shift”. Implications for fMRI studies as well as for public health in learning and performance environments including susceptible persons are discussed.

  11. Acoustic noise alters selective attention processes as indicated by direct current (DC) brain potential changes.

    Science.gov (United States)

    Trimmel, Karin; Schätzer, Julia; Trimmel, Michael

    2014-09-26

    Acoustic environmental noise, even of low to moderate intensity, is known to adversely affect information processing in animals and humans via attention mechanisms. In particular, facilitation and inhibition of information processing are basic functions of selective attention. Such mechanisms can be investigated by analyzing brain potentials under conditions of externally directed attention (intake of environmental information) versus internally directed attention (rejection of environmental stimuli and focusing on memory/planning processes). This study investigated brain direct current (DC) potential shifts-which are discussed to represent different states of cortical activation-of tasks that require intake and rejection of environmental information under noise. It was hypothesized that without background noise rejection tasks would show more positive DC potential changes compared to intake tasks and that under noise both kinds of tasks would show positive DC shifts as an expression of cortical inhibition caused by noise. DC potential shifts during intake and rejection tasks were analyzed at 16 standard locations in 45 persons during irrelevant speech or white noise vs. control condition. Without noise, rejection tasks were associated with more positive DC potential changes compared to intake tasks. During background noise, however, this difference disappeared and both kinds of tasks led to positive DC shifts. Results suggest-besides some limitations-that noise modulates selective attention mechanisms by switching to an environmental information processing and noise rejection mode, which could represent a suggested "attention shift". Implications for fMRI studies as well as for public health in learning and performance environments including susceptible persons are discussed.

  12. Second generation bioethanol potential from selected Malaysia's biodiversity biomasses: A review.

    Science.gov (United States)

    Aditiya, H B; Chong, W T; Mahlia, T M I; Sebayang, A H; Berawi, M A; Nur, Hadi

    2016-01-01

    Rising global temperature, worsening air quality and drastic declining of fossil fuel reserve are the inevitable phenomena from the disorganized energy management. Bioethanol is believed to clear out the effects as being an energy-derivable product sourced from renewable organic sources. Second generation bioethanol interests many researches from its unique source of inedible biomass, and this paper presents the potential of several selected biomasses from Malaysia case. As one of countries with rich biodiversity, Malaysia holds enormous potential in second generation bioethanol production from its various agricultural and forestry biomasses, which are the source of lignocellulosic and starch compounds. This paper reviews potentials of biomasses and potential ethanol yield from oil palm, paddy (rice), pineapple, banana and durian, as the common agricultural waste in the country but uncommon to be served as bioethanol feedstock, by calculating the theoretical conversion of cellulose, hemicellulose and starch components of the biomasses into bioethanol. Moreover, the potential of the biomasses as feedstock are discussed based on several reported works.

  13. Potential benefits of genomic selection on genetic gain of small ruminant breeding programs.

    Science.gov (United States)

    Shumbusho, F; Raoul, J; Astruc, J M; Palhiere, I; Elsen, J M

    2013-08-01

    In conventional small ruminant breeding programs, only pedigree and phenotype records are used to make selection decisions but prospects of including genomic information are now under consideration. The objective of this study was to assess the potential benefits of genomic selection on the genetic gain in French sheep and goat breeding designs of today. Traditional and genomic scenarios were modeled with deterministic methods for 3 breeding programs. The models included decisional variables related to male selection candidates, progeny testing capacity, and economic weights that were optimized to maximize annual genetic gain (AGG) of i) a meat sheep breeding program that improved a meat trait of heritability (h(2)) = 0.30 and a maternal trait of h(2) = 0.09 and ii) dairy sheep and goat breeding programs that improved a milk trait of h(2) = 0.30. Values of ±0.20 of genetic correlation between meat and maternal traits were considered to study their effects on AGG. The Bulmer effect was accounted for and the results presented here are the averages of AGG after 10 generations of selection. Results showed that current traditional breeding programs provide an AGG of 0.095 genetic standard deviation (σa) for meat and 0.061 σa for maternal trait in meat breed and 0.147 σa and 0.120 σa in sheep and goat dairy breeds, respectively. By optimizing decisional variables, the AGG with traditional selection methods increased to 0.139 σa for meat and 0.096 σa for maternal traits in meat breeding programs and to 0.174 σa and 0.183 σa in dairy sheep and goat breeding programs, respectively. With a medium-sized reference population (nref) of 2,000 individuals, the best genomic scenarios gave an AGG that was 17.9% greater than with traditional selection methods with optimized values of decisional variables for combined meat and maternal traits in meat sheep, 51.7% in dairy sheep, and 26.2% in dairy goats. The superiority of genomic schemes increased with the size of the

  14. The Local Atmosphere and the Turbulent Heat Transfer in the Eastern Himalayas

    Institute of Scientific and Technical Information of China (English)

    ZOU Han; LI Peng; MA Shupo; ZHOU Libo; ZHU Jinhuan

    2012-01-01

    To understand the local atmosphere and heat transfer and to facilitate the boundary-layer parameterization of numerical simulation and prediction,an observational campaign was conducted in the Eastern Himalayas in June 2010.The local atmospheric properties and near-surface turbulent heat transfers were analyzed.The local atmosphere in this region is warmer,more humid and less windy,with weaker solar radiation and surface radiate heating than in the Middle Himalayas.The near-surface turbulent heat transfer in the Eastern Himalayas is weaker than that in the Middle Himalayas.The total heat transfer is mainly contributed by the latent heat transfer with a Bowen ratio of 0.36,which is essentially different from that in the Middle Himalayas and the other Tibetan regions.

  15. Antimalarial activity of potential inhibitors of Plasmodium falciparum lactate dehydrogenase enzyme selected by docking studies.

    Directory of Open Access Journals (Sweden)

    Julia Penna-Coutinho

    Full Text Available The Plasmodium falciparum lactate dehydrogenase enzyme (PfLDH has been considered as a potential molecular target for antimalarials due to this parasite's dependence on glycolysis for energy production. Because the LDH enzymes found in P. vivax, P. malariae and P. ovale (pLDH all exhibit ∼90% identity to PfLDH, it would be desirable to have new anti-pLDH drugs, particularly ones that are effective against P. falciparum, the most virulent species of human malaria. Our present work used docking studies to select potential inhibitors of pLDH, which were then tested for antimalarial activity against P. falciparum in vitro and P. berghei malaria in mice. A virtual screening in DrugBank for analogs of NADH (an essential cofactor to pLDH and computational studies were undertaken, and the potential binding of the selected compounds to the PfLDH active site was analyzed using Molegro Virtual Docker software. Fifty compounds were selected based on their similarity to NADH. The compounds with the best binding energies (itraconazole, atorvastatin and posaconazole were tested against P. falciparum chloroquine-resistant blood parasites. All three compounds proved to be active in two immunoenzymatic assays performed in parallel using monoclonals specific to PfLDH or a histidine rich protein (HRP2. The IC(50 values for each drug in both tests were similar, were lowest for posaconazole (<5 µM and were 40- and 100-fold less active than chloroquine. The compounds reduced P. berghei parasitemia in treated mice, in comparison to untreated controls; itraconazole was the least active compound. The results of these activity trials confirmed that molecular docking studies are an important strategy for discovering new antimalarial drugs. This approach is more practical and less expensive than discovering novel compounds that require studies on human toxicology, since these compounds are already commercially available and thus approved for human use.

  16. Genome-wide association analysis of bacterial cold water disease resistance in rainbow trout reveals the potential of a hybrid approach between genomic selection and marker assisted selection

    Science.gov (United States)

    Genomic selection (GS) simultaneously incorporates dense SNP marker genotypes with phenotypic data from related animals to predict animal-specific genomic breeding value (GEBV), which circumvents the need to measure the disease phenotype in potential breeders. Marker assisted selection (MAS) involv...

  17. Genetic progress and potential of common bean families obtained by recurrent selection

    Directory of Open Access Journals (Sweden)

    Anatércia Ferreira Alves

    2015-12-01

    Full Text Available The objective of this study was to estimate the genetic gain of two recurrent selection cycles in common bean breeding and identify families with the potential to generate superior lines. The base population, cycle zero (C0, was obtained by combining 20 carioca bean parents, populations with favorable phenotypes for several agronomically important traits. The parents were recombined in a circulant diallel scheme, in which each parent participated in two crosses, generating 20 populations. From these populations, families were derived and evaluated for three seasons in the generations F2:3, F2:4 and F2:5. The same procedures of recombination and evaluation in C0 were performed in cycle one (CI. The genetic gain for yield, estimated from the simultaneous evaluation of the 40 best families of each cycle, was 8.6%. Families with potential to generate superior lines to cultivar Pérola were identified, especially among the CI families.

  18. Selective potentiation of NMDA-induced neuronal injury following induction of astrocytic iNOS.

    Science.gov (United States)

    Hewett, S J; Csernansky, C A; Choi, D W

    1994-08-01

    Nitric oxide (NO) produced by the constitutive NO synthase (cNOS) in neurons has been implicated in mediating excitotoxic neuronal death. In our murine cortical cell culture system, NMDA neurotoxicity was not blocked by addition of the NOS inhibitors, NG-nitro-L-arginine or aminoguanidine. However, following activation of inducible NOS in astrocytes by interleukin-1 beta plus interferon-gamma, NMDA but not kainate neurotoxicity was markedly potentiated. This selective potentiation of NMDA neurotoxicity was blocked by NOS inhibition or antioxidants (superoxide dismutase/catalase or Tempol) and could be mimicked by NO generators (SIN-1 or SNAP) or the oxygen radical generator, pyragallol. These results raise the possibility that NO production by astrocytes may contribute to NMDA receptor-mediated neuronal death, perhaps through interaction with oxygen radicals.

  19. Antioxidant properties and UPLC-MS/MS profiling of phenolics in jacquemont's hazelnut kernels (Corylus jacquemontii) and its byproducts from western Himalaya.

    Science.gov (United States)

    Kumar, Ashish; Kumar, Pawan; Koundal, Rajkesh; Agnihotri, Vijai K

    2016-09-01

    A rapid and selective analytical method was developed to simultaneously quantify seven polyphenolic compounds (gallic acid, catechin, epicatechin, quercetin, kaempferol, syringic acid and p-coumaric acid). 15 phenolics of diverse groups in 80 % ethanolic extracts of jacquemont's hazelnut (Corylus jacquemontii) kernels and its byproducts from western Himalaya using ultra-performance liquid chromatography coupled with tandem mass spectrometry (UPLC-MS/MS) were identified. The developed analytical method showed excellent linearity, repeatability and accuracy. Total phenols concentrations were found to be 4446, 1199 and 105 mg gallic acid equivalent (GAE)/Kg of dried extract for jacquemont's hazelnut skin, hard shell and kernels respectively. Antioxidant potential of defatted, raw jacquemont's hazelnut skin, hard shell and kernel extracts assessed by 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS), 2,2'-diphenyl-1-picrylhydrazyl (DPPH) methods were increased in a dose-dependent manner. The IC50 values were observed as 23.12, 51.32, 136.46 and 45.73, 63.65, 169.30 μg/ml for jacquemont's hazelnut skin, hard shell, kernels by DPPH and ABTS assays, respectively. The high phenolic contents in jacquemont's hazelnut skin contributed towards their free radical scavenging capacities.

  20. Selection of commercial hydrolytic enzymes with potential antifouling activity in marine environments.

    Science.gov (United States)

    Zanaroli, Giulio; Negroni, Andrea; Calisti, Cecilia; Ruzzi, Maurizio; Fava, Fabio

    2011-12-10

    In this work, the marine antifouling potential of some commercially available hydrolytic enzymes acting on the main constituents of extracellular polymeric substances (EPS) involved in bacterial biofilm formation was determined. The selected protease (i.e., alpha-chymotrypsin from bovine pancreas), carbohydrase (i.e., alpha-amylase from porcine pancreas) and lipase (from porcine pancreas) exhibited remarkable hydrolytic activities towards target macromolecules typically composing EPS under a wide range of pHs (6.5-9.0 for alpha-chymotrysin and alpha-amylase; 7.0-8.5 for the lipase) and temperatures (from 10 °C to 30 °C), as well as relevant half-lives (from about 2 weeks to about 2 months), in a marine synthetic water. The activity displayed by each enzyme was poorly affected by the co-presence of the other enzymes, thus indicating their suitability to be employed in combination. None of the enzymes was able to inhibit the formation of biofilm by an actual site marine microbial community when applied singly. However, a mixture of the same enzymes reduced biofilm formation by about 90% without affecting planktonic growth of the same microbial community. This indicates that multiple hydrolytic activities are required to efficiently prevent biofilm formation by complex microbial communities, and that the mixture of enzymes selected in this study has the potential to be employed as an environmental friendly antifouling agent in marine antifouling coatings.

  1. Granulometric selectivity in Liza ramado and potential contamination resulting from heavy metal load in feeding areas

    Science.gov (United States)

    Pedro, Sílvia; Canastreiro, Vera; Caçador, Isabel; Pereira, Eduarda; Duarte, Armando C.; Raposo de Almeida, Pedro

    2008-11-01

    The stomach contents of thin-lipped grey mullets Liza ramado were analysed in terms of granulometric composition and compared to the sediment of potential feeding areas in the Tagus estuary. Total organic matter (TOM) content and heavy metal content were determined in the surface sediment of three areas and eight trace elements were quantified: Cd, Co, Cr, Cu, Hg, Ni, Pb and Zn. The three sampled areas did not differ in TOM; and the heavy metal content was below Effects Range-Low level for most elements. The mean observed concentrations were present in the following sequence: Zn > Pb > Cr > Cu ≈ Ni > Co > Cd > Hg. Stomach contents granulometric composition provided information about the feeding selectivity of the mullets. Sediment fractions with particle size between 20 and 50 μm are preferred, independently of the fishes' length. Smaller standard length (SL) fishes have a higher positive selection of fine grained sediments than those with a larger SL. Finer fractions usually have higher concentration of heavy metals, which makes younger specimens of the thin-lipped grey mullet potentially more exposed to heavy metal load in the estuary. Metal concentration was not independent from the sampling point, presenting higher values near the margins and the estuary tidal drainage system. This means that during the first period of each tidal cycle, the mullets will feed first on the most contaminated areas, as a consequence of their movement following the rising tide to feed on previously exposed areas.

  2. Lepidopteran HMG-CoA reductase is a potential selective target for pest control

    Directory of Open Access Journals (Sweden)

    Yuan-mei Li

    2017-01-01

    Full Text Available As a consequence of the negative impacts on the environment of some insecticides, discovery of eco-friendly insecticides and target has received global attention in recent years. Sequence alignment and structural comparison of the rate-limiting enzyme HMG-CoA reductase (HMGR revealed differences between lepidopteran pests and other organisms, which suggested insect HMGR could be a selective insecticide target candidate. Inhibition of JH biosynthesis in vitro confirmed that HMGR inhibitors showed a potent lethal effect on the lepidopteran pest Manduca sexta, whereas there was little effect on JH biosynthesis in Apis mellifera and Diploptera punctata. The pest control application of these inhibitors demonstrated that they can be insecticide candidates with potent ovicidal activity, larvicidal activity and insect growth regulatory effects. The present study has validated that Lepidopteran HMGR can be a potent selective insecticide target, and the HMGR inhibitors (especially type II statins could be selective insecticide candidates and lead compounds. Furthermore, we demonstrated that sequence alignment, homology modeling and structural comparison may be useful for determining potential enzymes or receptors which can be eco-friendly pesticide  targets.

  3. Lepidopteran HMG-CoA reductase is a potential selective target for pest control

    Science.gov (United States)

    Li, Yuan-mei; Huang, Juan; Tobe, Stephen S.

    2017-01-01

    As a consequence of the negative impacts on the environment of some insecticides, discovery of eco-friendly insecticides and target has received global attention in recent years. Sequence alignment and structural comparison of the rate-limiting enzyme HMG-CoA reductase (HMGR) revealed differences between lepidopteran pests and other organisms, which suggested insect HMGR could be a selective insecticide target candidate. Inhibition of JH biosynthesis in vitro confirmed that HMGR inhibitors showed a potent lethal effect on the lepidopteran pest Manduca sexta, whereas there was little effect on JH biosynthesis in Apis mellifera and Diploptera punctata. The pest control application of these inhibitors demonstrated that they can be insecticide candidates with potent ovicidal activity, larvicidal activity and insect growth regulatory effects. The present study has validated that Lepidopteran HMGR can be a potent selective insecticide target, and the HMGR inhibitors (especially type II statins) could be selective insecticide candidates and lead compounds. Furthermore, we demonstrated that sequence alignment, homology modeling and structural comparison may be useful for determining potential enzymes or receptors which can be eco-friendly pesticide  targets. PMID:28133568

  4. Altitudinal variation of soil organic carbon stocks in temperate forests of Kashmir Himalayas, India.

    Science.gov (United States)

    Ahmad Dar, Javid; Somaiah, Sundarapandian

    2015-02-01

    Soil organic carbon stocks were measured at three depths (0-10, 10-20, and 20-30 cm) in seven altitudes dominated by different forest types viz. Populus deltoides, 1550-1800 m; Juglans regia, 1800-2000 m; Cedrus deodara, 2050-2300 m; Pinus wallichiana, 2000-2300 m; mixed type, 2200-2400 m; Abies pindrow, 2300-2800 m; and Betula utilis, 2800-3200 m in temperate mountains of Kashmir Himalayas. The mean range of soil organic carbon (SOC) stocks varied from 39.07 to 91.39 Mg C ha(-1) in J. regia and B. utilis forests at 0-30 cm depth, respectively. Among the forest types, the lowest mean range of SOC at three depths (0-10, 10-20, and 20-30 cm) was observed in J. regia (18.55, 11.31, and 8.91 Mg C ha(-1), respectively) forest type, and the highest was observed in B. utilis (54.10, 21.68, and 15.60 Mg C ha(-1), respectively) forest type. SOC stocks showed significantly (R (2) = 0.67, P = 0.001) an increasing trend with increase in altitude. On average, the percentages of SOC at 0-10-, 10-20-, and 20-30-cm depths were 53.2, 26.5, and 20.3 %, respectively. Bulk density increased significantly with increase in soil depth and decreased with increase in altitude. Our results suggest that SOC stocks in temperate forests of Kashmir Himalaya vary greatly with forest type and altitude. The present study reveals that SOC stocks increased with increase in altitude at high mountainous regions. Climate change in these high mountainous regions will alter the carbon sequestration potential, which would affect the global carbon cycle.

  5. Framing hydropower as green energy: assessing drivers, risks and tensions in the Eastern Himalayas

    Science.gov (United States)

    Ahlers, R.; Budds, J.; Joshi, D.; Merme, V.; Zwarteveen, M.

    2015-04-01

    The culturally and ecologically diverse region of the Eastern Himalayas is the target of ambitious hydropower development plans. Policy discourses at national and international levels position this development as synergistically positive: it combines the production of clean energy to fuel economic growth at regional and national levels with initiatives to lift poor mountain communities out of poverty. Different from hydropower development in the 20th century in which development agencies and banks were important players, contemporary initiatives importantly rely on the involvement of private actors, with a prominent role of the private finance sector. This implies that hydropower development is not only financially viable but also understood as highly profitable. This paper examines the new development of hydropower in the Eastern Himalayas of Nepal and India. It questions its framing as green energy, interrogates its links with climate change, and examines its potential for investment and capital accumulation. To do this, we also review the evidence on the extent to which its construction and operation may modify existing hydrogeological processes and ecosystems, as well as its impacts on the livelihoods of diverse groups of people that depend on these. The paper concludes that hydropower development in the region is characterized by inherent contentions and uncertainties, refuting the idea that dams constitute development projects whose impacts can be simply predicted, controlled and mitigated. Indeed, in a highly complex geological, ecological, cultural and political context that is widely regarded to be especially vulnerable to the effects of climate change, hydropower as a development strategy makes for a toxic cocktail.

  6. Phenotypic variation and water selection potential in the stem structure of invasive alligator weed

    Science.gov (United States)

    Du, Leshan; Yang, Beifen; Guan, Wenbin; Li, Junmin

    2016-02-01

    The morphological and anatomical characteristics of stems have been found to be related to drought resistance in plants. Testing the phenotypic selection of water availability on stem anatomical traits would be useful for exploring the evolutionary potential of the stem in response to water availability. To test the phenotypic variation of the stem anatomical traits of an invasive plant in response to water availability, we collected a total of 320 individuals of Alternanthera philoxeroides from 16 populations from terrestrial and aquatic habitats in 8 plots in China and then analyzed the variation, differentiation, plasticity and selection potential of water availability on the stem anatomical traits. We found that except for the thickness of the cortex, all of the examined phenotypic parameters of the A. philoxeroides stem were significantly and positively correlated with soil water availability. The phenotypic differentiation coefficient for all of the anatomical structural parameters indicated that most of the variation existed between habitats within the same plot, whereas there was little variation among plots or among individuals within the same habitat except for variation in the thickness of the cortex. A significant phenotypic plasticity response to water availability was found for all of the anatomical traits of A. philoxeroides stem except for the thickness of the cortex. The associations between fitness and some of the anatomical traits, such as the stem diameter, the cortex area-to-stem area ratio, the pith cavity area-to-stem area ratio and the density of vascular bundles, differed with heterogeneous water availability. In both the aquatic and terrestrial habitats, no significant directional selection gradient was found for the stem diameter, the cortex area-to-stem area ratio or the density of vascular bundles. These results indicated that the anatomical structure of the A. philoxeroides stem may play an important role in the adaptation to changes

  7. Modelling the Crust beneath the Kashmir valley in Northwestern Himalaya

    Science.gov (United States)

    Mir, R. R.; Parvez, I. A.; Gaur, V. K.; A.; Chandra, R.; Romshoo, S. A.

    2015-12-01

    We investigate the crustal structure beneath five broadband seismic stations in the NW-SE trendingoval shaped Kashmir valley sandwiched between the Zanskar and the Pir Panjal ranges of thenorthwestern Himalaya. Three of these sites were located along the southwestern edge of the valley andthe other two adjoined the southeastern. Receiver Functions (RFs) at these sites were calculated usingthe iterative time domain deconvolution method and jointly inverted with surface wave dispersiondata to estimate the shear wave velocity structure beneath each station. To further test the results ofinversion, we applied forward modelling by dividing the crust beneath each station into 4-6homogeneous, isotropic layers. Moho depths were separately calculated at different piercing pointsfrom the inversion of only a few stacked receiver functions of high quality around each piercing point.These uncertainties were further reduced to ±2 km by trial forward modelling as Moho depths werevaried over a range of ±6 km in steps of 2 km and the synthetic receiver functions matched with theinverted ones. The final values were also found to be close to those independently estimated using theH-K stacks. The Moho depths on the eastern edge of the valley and at piercing points in itssouthwestern half are close to 55 km, but increase to about 58 km on the eastern edge, suggesting thathere, as in the central and Nepal Himalaya, the Indian plate dips northeastwards beneath the Himalaya.We also calculated the Vp/Vs ratio beneath these 5 stations which were found to lie between 1.7 and1.76, yielding a Poisson's ratio of ~0.25 which is characteristic of a felsic composition.

  8. Genetic parameters for predicted methane production and potential for reducing enteric emissions through genomic selection.

    Science.gov (United States)

    Haas, Y de; Windig, J J; Calus, M P L; Dijkstra, J; Haan, M de; Bannink, A; Veerkamp, R F

    2011-12-01

    Mitigation of enteric methane (CH₄) emission in ruminants has become an important area of research because accumulation of CH₄ is linked to global warming. Nutritional and microbial opportunities to reduce CH₄ emissions have been extensively researched, but little is known about using natural variation to breed animals with lower CH₄ yield. Measuring CH₄ emission rates directly from animals is difficult and hinders direct selection on reduced CH₄ emission. However, improvements can be made through selection on associated traits (e.g., residual feed intake, RFI) or through selection on CH₄ predicted from feed intake and diet composition. The objective was to establish phenotypic and genetic variation in predicted CH₄ output, and to determine the potential of genetics to reduce methane emissions in dairy cattle. Experimental data were used and records on daily feed intake, weekly body weights, and weekly milk production were available from 548 heifers. Residual feed intake (MJ/d) is the difference between net energy intake and calculated net energy requirements for maintenance as a function of body weight and for fat- and protein-corrected milk production. Predicted methane emission (PME; g/d) is 6% of gross energy intake (Intergovernmental Panel on Climate Change methodology) corrected for energy content of methane (55.65 kJ/g). The estimated heritabilities for PME and RFI were 0.35 and 0.40, respectively. The positive genetic correlation between RFI and PME indicated that cows with lower RFI have lower PME (estimates ranging from 0.18 to 0.84). Hence, it is possible to decrease the methane production of a cow by selecting more-efficient cows, and the genetic variation suggests that reductions in the order of 11 to 26% in 10 yr are theoretically possible, and could be even higher in a genomic selection program. However, several uncertainties are discussed; for example, the lack of true methane measurements (and the key assumption that methane

  9. The Large-Bodied hominoids of the Himalayas

    Directory of Open Access Journals (Sweden)

    Michael Trachtengerts

    2012-11-01

    Full Text Available The review of available data concerning to large-bodied hominoids detected in the Himalayas is presented. They are mainly footprints (photographs by E.Shipton and M.Ward, P.Bordet, F.Smythe, and A.Woodridge and also narration of one remote observation. It is shown that on the whole these data reveal basic features of the undefined creature, most probably humanlike primate, and allow describing it as a separate species. One of its features is unusual four-toed foot with two strong toes and two small toes. A taxonomic name for this hominoid is proposed ¾ Homo pardigitatus sp. nov. ("That has paired toes".

  10. Clockwise rotation of the Brahmaputra Valley relative to India: Tectonic convergence in the eastern Himalaya, Naga Hills, and Shillong Plateau

    Science.gov (United States)

    Vernant, P.; Bilham, R.; Szeliga, W.; Drupka, D.; Kalita, S.; Bhattacharyya, A. K.; Gaur, V. K.; Pelgay, P.; Cattin, R.; Berthet, T.

    2014-08-01

    GPS data reveal that the Brahmaputra Valley has broken from the Indian Plate and rotates clockwise relative to India about a point a few hundred kilometers west of the Shillong Plateau. The GPS velocity vectors define two distinct blocks separated by the Kopili fault upon which 2-3 mm/yr of dextral slip is observed: the Shillong block between longitudes 89 and 93°E rotating clockwise at 1.15°/Myr and the Assam block from 93.5°E to 97°E rotating at ≈1.13°/Myr. These two blocks are more than 120 km wide in a north-south sense, but they extend locally a similar distance beneath the Himalaya and Tibet. A result of these rotations is that convergence across the Himalaya east of Sikkim decreases in velocity eastward from 18 to ≈12 mm/yr and convergence between the Shillong Plateau and Bangladesh across the Dauki fault increases from 3 mm/yr in the west to >8 mm/yr in the east. This fast convergence rate is inconsistent with inferred geological uplift rates on the plateau (if a 45°N dip is assumed for the Dauki fault) unless clockwise rotation of the Shillong block has increased substantially in the past 4-8 Myr. Such acceleration is consistent with the reported recent slowing in the convergence rate across the Bhutan Himalaya. The current slip potential near Bhutan, based on present-day convergence rates and assuming no great earthquake since 1713 A.D., is now ~5.4 m, similar to the slip reported from alluvial terraces that offsets across the Main Himalayan Thrust and sufficient to sustain a Mw ≥ 8.0 earthquake in this area.

  11. New Constraints on the Geometry and Kinematics of Active Faults in the Hinterland of the Northwest Himalaya

    Science.gov (United States)

    Morell, K. D.; Sandiford, M.; Rajendran, C. C. P.; Fink, D.; Kohn, B. P.

    2014-12-01

    The geometry and kinematics of the active, and potentially seismogenic, fault structures within the hinterland of the Himalaya have proven challenging to constrain in the past, primarily because active faults in this region tend to be buried beneath the subsurface and active seismicity often does not align with surficially mapped fault traces. Here we present a series of complementary datasets, including results from low temperature thermochronology, basin-wide erosion rates from 10Be concentrations, and topographic and longitudinal profile analyses, that place constraints on the spatial distribution of fault-related rock uplift and erosion across a ~400-km long region of the lower and high Himalaya of northwest India. Results from our analyses reveal that hillslope morphology and channel steepness are relatively invariant parallel to strike but vary significantly across strike, with the most prominent and abrupt variations occurring at the physiographic transition between the lower and high Himalaya (PT2), near the axial trace of the ramp-flat transition in the Main Himalayan Thrust (MHT). The cross-strike changes in geomorphology observed across the PT2 correlate with an order of magnitude northward increase in basin-wide erosion rates (~0.06-0.8 mm/a) and a corresponding decrease in apatite (~5-2 Ma) and zircon (U-Th)/He (~10-2 Ma) cooling ages. Combined with published geophysical and seismicity data, we interpret these results to reflect spatial variations in rock uplift and exhumation induced by a segment of the MHT ramp-flat system that is at least ~400 km long and ~125 km wide. The relatively young (U-Th)/He ages (flat transition preliminarily suggest that the kinematics of this system are best explained by a model which incorporates an accreting duplex on the MHT ramp but additional forthcoming analyses, including thermal modeling, will confirm if this hypothesis is robust.

  12. Mass, charge, and energy separation by selective acceleration with a traveling potential hill

    Science.gov (United States)

    Tung, L. Schwager; Barr, W. L.; Lowder, R. S.; Post, R. F.

    1996-10-01

    A traveling electric potential hill has been used to generate an ion beam with an energy distribution that is mass dependent from a monoenergetic ion beam of mixed masses. This effect can be utilized as a novel method for mass separation applied to identification or enrichment of ions (e.g., of elements, isotopes, or molecules). This theory for mass-selective acceleration is presented here and is shown to be confirmed by experiment and by a time-dependent particle-in-cell computer simulation. Results show that monoenergetic ions with the particular mass of choice are accelerated by controlling the hill potential and the hill velocity. The hill velocity is typically 20%-30% faster than the ions to be accelerated. The ability of the hill to pickup a particular mass uses the fact that small kinetic energy differences in the lab frame appear much larger in the moving hill frame. Ions will gain energy from the approaching hill if their relative energy in the moving hill frame is less than the peak potential of the hill. The final energy of these accelerated ions can be several times the source energy, which facilitates energy filtering for mass purification or identification. If the hill potential is chosen to accelerate multiple masses, the heaviest mass will have the greatest final energy. Hence, choosing the appropriate hill potential and collector retarding voltage will isolate ions with the lightest, heaviest, or intermediate mass. In the experimental device, called a Solitron, purified 20Ne and 22Ne are extracted from a ribbon beam of neon that is originally composed of 20Ne:22Ne in the natural ratio of 91:9. The isotopic content of the processed beam is determined by measuring the energy distribution of the detected current. These results agree with the theory. In addition to mass selectivity, our theory can also be applied to the filtration of an ion beam according to charge state or energy. Because of this variety of properties, the Solitron is envisioned to

  13. Function-selective domain architecture plasticity potentials in eukaryotic genome evolution.

    Science.gov (United States)

    Linkeviciute, Viktorija; Rackham, Owen J L; Gough, Julian; Oates, Matt E; Fang, Hai

    2015-12-01

    To help evaluate how protein function impacts on genome evolution, we introduce a new concept of 'architecture plasticity potential' - the capacity to form distinct domain architectures - both for an individual domain, or more generally for a set of domains grouped by shared function. We devise a scoring metric to measure the plasticity potential for these domain sets, and evaluate how function has changed over time for different species. Applying this metric to a phylogenetic tree of eukaryotic genomes, we find that the involvement of each function is not random but highly selective. For certain lineages there is strong bias for evolution to involve domains related to certain functions. In general eukaryotic genomes, particularly animals, expand complex functional activities such as signalling and regulation, but at the cost of reducing metabolic processes. We also observe differential evolution of transcriptional regulation and a unique evolutionary role of channel regulators; crucially this is only observable in terms of the architecture plasticity potential. Our findings provide a new layer of information to understand the significance of function in eukaryotic genome evolution. A web search tool, available at http://supfam.org/Pevo, offers a wide spectrum of options for exploring functional importance in eukaryotic genome evolution.

  14. Selective serotonin reuptake inhibitor antidepressants potentiate methylphenidate (Ritalin)-induced gene regulation in the adolescent striatum.

    Science.gov (United States)

    Van Waes, Vincent; Beverley, Joel; Marinelli, Michela; Steiner, Heinz

    2010-08-01

    The psychostimulant methylphenidate (Ritalin) is used in conjunction with selective serotonin reuptake inhibitors (SSRIs) in the treatment of medical conditions such as attention-deficit hyperactivity disorder with anxiety/depression comorbidity and major depression. Co-exposure also occurs in patients on SSRIs who use psychostimulant 'cognitive enhancers'. Methylphenidate is a dopamine/norepinephrine reuptake inhibitor that produces altered gene expression in the forebrain; these effects partly mimic gene regulation by cocaine (dopamine/norepinephrine/serotonin reuptake inhibitor). We investigated whether the addition of SSRIs (fluoxetine or citalopram; 5 mg/kg) modified gene regulation by methylphenidate (2-5 mg/kg) in the striatum and cortex of adolescent rats. Our results show that SSRIs potentiate methylphenidate-induced expression of the transcription factor genes zif268 and c-fos in the striatum, rendering these molecular changes more cocaine-like. Present throughout most of the striatum, this potentiation was most robust in its sensorimotor parts. The methylphenidate + SSRI combination also enhanced behavioral stereotypies, consistent with dysfunction in sensorimotor striatal circuits. In so far as such gene regulation is implicated in psychostimulant addiction, our findings suggest that SSRIs may enhance the addiction potential of methylphenidate.

  15. Selective attention and the auditory vertex potential. 2: Effects of signal intensity and masking noise

    Science.gov (United States)

    Schwent, V. L.; Hillyard, S. A.; Galambos, R.

    1975-01-01

    A randomized sequence of tone bursts was delivered to subjects at short inter-stimulus intervals with the tones originating from one of three spatially and frequency specific channels. The subject's task was to count the tones in one of the three channels at a time, ignoring the other two, and press a button after each tenth tone. In different conditions, tones were given at high and low intensities and with or without a background white noise to mask the tones. The N sub 1 component of the auditory vertex potential was found to be larger in response to attended channel tones in relation to unattended tones. This selective enhancement of N sub 1 was minimal for loud tones presented without noise and increased markedly for the lower tone intensity and in noise added conditions.

  16. Potential of Radiotelescopes for Atmospheric Line Observations: I. Observation Principles and Transmission Curves for Selected Sites

    CERN Document Server

    Schneider, Nicola; Baron, Philippe

    2009-01-01

    Existing and planned radiotelescopes working in the millimetre (mm) and sub-millimetre wavelengths range provide the possibility to be used for atmospheric line observations. To scrutinize this potential, we outline the differences and similarities in technical equipment and observing techniques between ground-based aeronomy mm-wave radiometers and radiotelescopes. Comprehensive tables summarizing the technical characteristics of existing and future (sub)-mm radiotelescopes are given. The advantages and disadvantages using radiotelescopes for atmospheric line observations are discussed. In view of the importance of exploring the sub-mm and far-infrared wavelengths range for astronomical observations and atmospheric sciences, we present model calculations of the atmospheric transmission for selected telescope sites (DOME-C/Antarctica, ALMA/Chajnantor, JCMT and CSO on Mauna Kea/Hawaii, KOSMA/Swiss Alpes) for frequencies between 0 and 2000 GHz (0 to 150 micron) and typical atmospheric conditions using the forwar...

  17. Acute stress alters auditory selective attention in humans independent of HPA: a study of evoked potentials.

    Directory of Open Access Journals (Sweden)

    Ludger Elling

    Full Text Available BACKGROUND: Acute stress is a stereotypical, but multimodal response to a present or imminent challenge overcharging an organism. Among the different branches of this multimodal response, the consequences of glucocorticoid secretion have been extensively investigated, mostly in connection with long-term memory (LTM. However, stress responses comprise other endocrine signaling and altered neuronal activity wholly independent of pituitary regulation. To date, knowledge of the impact of such "paracorticoidal" stress responses on higher cognitive functions is scarce. We investigated the impact of an ecological stressor on the ability to direct selective attention using event-related potentials in humans. Based on research in rodents, we assumed that a stress-induced imbalance of catecholaminergic transmission would impair this ability. METHODOLOGY/PRINCIPAL FINDINGS: The stressor consisted of a single cold pressor test. Auditory negative difference (Nd and mismatch negativity (MMN were recorded in a tonal dichotic listening task. A time series of such tasks confirmed an increased distractibility occurring 4-7 minutes after onset of the stressor as reflected by an attenuated Nd. Salivary cortisol began to rise 8-11 minutes after onset when no further modulations in the event-related potentials (ERP occurred, thus precluding a causal relationship. This effect may be attributed to a stress-induced activation of mesofrontal dopaminergic projections. It may also be attributed to an activation of noradrenergic projections. Known characteristics of the modulation of ERP by different stress-related ligands were used for further disambiguation of causality. The conjuncture of an attenuated Nd and an increased MMN might be interpreted as indicating a dopaminergic influence. The selective effect on the late portion of the Nd provides another tentative clue for this. CONCLUSIONS/SIGNIFICANCE: Prior studies have deliberately tracked the adrenocortical influence

  18. Assessing the potential for egg chemoattractants to mediate sexual selection in a broadcast spawning marine invertebrate.

    Science.gov (United States)

    Evans, Jonathan P; Garcia-Gonzalez, Francisco; Almbro, Maria; Robinson, Oscar; Fitzpatrick, John L

    2012-07-22

    In numerous species, egg chemoattractants play a critical role in guiding sperm towards unfertilized eggs (sperm chemotaxis). Until now, the known functions of sperm chemotaxis include increasing the effective target size of eggs, thereby promoting sperm-egg encounters, and facilitating species recognition. Here, we report that in the broadcast spawning mussel, Mytilus galloprovincialis, egg chemoattractants may play an unforeseen role in sexual selection by enabling sperm to effectively 'choose' between the eggs of different conspecific females. In an initial experiment, we confirmed that sperm chemotaxis occurs in M. galloprovincialis by showing that sperm are attracted towards unfertilized eggs when given the choice of eggs or no eggs in a dichotomous chamber. We then conducted two cross-classified mating experiments, each comprising the same individual males and females crossed in identical male × female combinations, but under experimental conditions that offered sperm 'no-choice' (each fertilization trial took place in a Petri dish and involved a single male and female) or a 'choice' of a female's eggs (sperm were placed in the centre of a dichotomous choice chamber and allowed to choose eggs from different females). We show that male-by-female interactions characterized fertilization rates in both experiments, and that there was remarkable consistency between patterns of sperm migration in the egg-choice experiment and fertilization rates in the no-choice experiment. Thus, sperm appear to exploit chemical cues to preferentially swim towards eggs with which they are most compatible during direct sperm-to-egg encounters. These results reveal that sperm differentially select eggs on the basis of chemical cues, thus exposing the potential for egg chemoattractants to mediate mate choice for genetically compatible partners. Given the prevalence of sperm chemotaxis across diverse taxa, our findings may have broad implications for sexual selection in other mating

  19. Influence of anode potentials on selection of Geobacter strains in microbial electrolysis cells.

    Science.gov (United States)

    Commault, Audrey S; Lear, Gavin; Packer, Michael A; Weld, Richard J

    2013-07-01

    Through their ability to directly transfer electrons to electrodes, Geobacter sp. are key organisms for microbial fuel cell technology. This study presents a simple method to reproducibly select Geobacter-dominated anode biofilms from a mixed inoculum of bacteria using graphite electrodes initially poised at -0.25, -0.36 and -0.42 V vs. Ag/AgCl. The biofilms all produced maximum power density of approximately 270 m Wm(-2) (projected anode surface area). Analysis of 16S rRNA genes and intergenic spacer (ITS) sequences found that the biofilm communities were all dominated by bacteria closely related to Geobacter psychrophilus. Anodes initially poised at -0.25 V reproducibly selected biofilms that were dominated by a strain of G. psychrophilus that was genetically distinct from the strain that dominated the -0.36 and -0.42 V biofilms. This work demonstrates for the first time that closely related strains of Geobacter can have very different competitive advantages at different anode potentials.

  20. Evaluation of functional potentiality of selected commonly consumed foods of Bangladesh

    Directory of Open Access Journals (Sweden)

    Nazma Shaheen

    2016-11-01

    Full Text Available Background: Rising tide of chronic nutrition related non-communicable diseases yoked with extant under nutrition problems makes it imperative to carry out scientific research towards the discovery of functional foods. Although the emergence of these diseases are believed to be related to a constellation of dietary, socio-economic and lifestyle related risk factors, central to the pathogenesis of these diseases (or disease states are free radicals, oxidative stress, and inflammatory processes typically accompanied by pain. Therefore, functional whole foods with physiologically active antioxidants, anti-inflammatory, and analgesic compounds seem to be the most promising option to deal with the pathogenesis of existing and emerging chronic diseases burden of Bangladesh. Methods: Edible portions of 70 commonly consumed Bangladeshi foods – including one cereal, five legumes, fourteen vegetables, four tea varieties, five oil seeds, twenty spices, and twenty one fruits – were evaluated for total phenol content (TPC by Folin-Ciocalteau assay. To evaluate functional potentiality, in vitro antioxidant capacity (AC of selected food items were evaluated by DPPH (2,2-diphenyl- 1-picrylhydrazyl radical scavenging assays, in vitro anti-inflammatory potential by observing the production of pro-inflammatory cytokine TNF-α using J774A.1 cells stimulated with lipopolysaccharide (LPS, in vivo anti-inflammatory potential by measuring carrageenan induced rat paw edema reduction, and in vivo analgesic potential by acetic acid induced writhing test in mice. Results: Spices, oilseeds, and teas showed high concentration of TPC among the analyzed foods, while spices and teas exhibited notable AC. Green tea showed highest concentrations of TPC (2349 mg Gallic Acid Equivalent / g and AC (2432 µmole Trolox Equivalent/g. Fourteen food items showed potential in vitro anti-inflammatory activity with confirmatory dose response effect shown by 8 items. In vivo, black sesame

  1. Soil-gas radon as seismotectonic indicator in Garhwal Himalaya.

    Science.gov (United States)

    Ramola, R C; Prasad, Yogesh; Prasad, Ganesh; Kumar, Sushil; Choubey, V M

    2008-10-01

    Research on earthquake-related radon monitoring has received enormous attention recently. Anomalous behaviour of radon in soil and groundwater can be used as a reliable precursor for an impending earthquake. While earthquake prediction may not yet be possible, earthquake prediction research has greatly increased our understanding of earthquake source mechanisms, the structural complexities of fault zones, and the earthquake recurrence interval, expected at a given location. This paper presents some results of continuous monitoring of radon in soil-gas in Garhwal Himalaya, India. Daily soil-gas radon monitoring with seismic activity and meteorological parameters were performed in the same laboratory system, located at H.N.B. Garhwal University Campus, Tehri Garhwal, India. Radon anomalies along with meteorological parameters were found to be statistically significant for the seismic events within the magnitudes M2.0-M6.0 and epicentral distances of 16-250 km from the monitoring station. The frequent positive and negative anomalies with constant environmental perturbation indicate the opening and closing of micro cracks within the volume of dilatancy by strain energy. The spike-like and sharp peak anomalies were recorded before, during and after earthquakes occurred in the area. The variations in radon concentrations in soil-gas are found to be correlated with seismic activities in the Garhwal Himalaya. The correlation between radon level and meteorological parameters is also discussed.

  2. Soil-gas radon as seismotectonic indicator in Garhwal Himalaya

    Energy Technology Data Exchange (ETDEWEB)

    Ramola, R.C. [Department of Physics, H. N. B. Garhwal University, Badshahi Thaul Campus, Tehri Garhwal-249199 (India)], E-mail: rcramola@gmail.com; Prasad, Yogesh; Prasad, Ganesh [Department of Physics, H. N. B. Garhwal University, Badshahi Thaul Campus, Tehri Garhwal-249199 (India); Kumar, Sushil; Choubey, V.M. [Wadia Institute of Himalayan Geology, Dehradun-248001 (India)

    2008-10-15

    Research on earthquake-related radon monitoring has received enormous attention recently. Anomalous behaviour of radon in soil and groundwater can be used as a reliable precursor for an impending earthquake. While earthquake prediction may not yet be possible, earthquake prediction research has greatly increased our understanding of earthquake source mechanisms, the structural complexities of fault zones, and the earthquake recurrence interval, expected at a given location. This paper presents some results of continuous monitoring of radon in soil-gas in Garhwal Himalaya, India. Daily soil-gas radon monitoring with seismic activity and meteorological parameters were performed in the same laboratory system, located at H.N.B. Garhwal University Campus, Tehri Garhwal, India. Radon anomalies along with meteorological parameters were found to be statistically significant for the seismic events within the magnitudes M2.0-M6.0 and epicentral distances of 16-250 km from the monitoring station. The frequent positive and negative anomalies with constant environmental perturbation indicate the opening and closing of micro cracks within the volume of dilatancy by strain energy. The spike-like and sharp peak anomalies were recorded before, during and after earthquakes occurred in the area. The variations in radon concentrations in soil-gas are found to be correlated with seismic activities in the Garhwal Himalaya. The correlation between radon level and meteorological parameters is also discussed.

  3. Denudational slope processes and slope response to global climate changes and other disturbances: insights from the Nepal Himalayas.

    Science.gov (United States)

    Fort, Monique

    2016-04-01

    Hillslope geomorphology results from a large range of denudational processes mainly controlled by relief, structure, lithology, climate, land-cover and land use. In most areas of the world, the "critical zone" concept is a good integrator of denudation that operates on a long-term scale. However, in large and high mountain areas, short-time scale factors often play a significant role in the denudational pattern, accelerating and/or delaying the transfer of denudation products and fluxes, and creating specific, spatially limited disturbances. We focus on the Nepal Himalayas, where the wide altitudinal range of bio-climatic zones and the intense geodynamic activity create a complex mosaic of landforms, as expressed by the present geomorphology of mountain slopes. On the basis of examples selected in the different Himalayan mountain belts (Siwaliks hills, middle mountains, High Himalaya), we illustrate different types of slopes and disturbances induced by active tectonics, climate extremes, and climate warming trends. Special attention is paid to recent events, such as landslide damming, triggered by either intense rainfalls (Kali Gandaki and Sun Kosi valleys) or the last April-May 2015 Gorkha seismic sequence (southern Khumbu). Lastly, references to older, larger events show that despite the highly dynamic environment, landforms caused by large magnitude disturbances may persist in the landscape in the long term.

  4. Predicting and mapping potential Whooping Crane stopover habitat to guide site selection for wind energy projects.

    Science.gov (United States)

    Belaire, J Amy; Kreakie, Betty J; Keitt, Timothy; Minor, Emily

    2014-04-01

    Migratory stopover habitats are often not part of planning for conservation or new development projects. We identified potential stopover habitats within an avian migratory flyway and demonstrated how this information can guide the site-selection process for new development. We used the random forests modeling approach to map the distribution of predicted stopover habitat for the Whooping Crane (Grus americana), an endangered species whose migratory flyway overlaps with an area where wind energy development is expected to become increasingly important. We then used this information to identify areas for potential wind power development in a U.S. state within the flyway (Nebraska) that minimize conflicts between Whooping Crane stopover habitat and the development of clean, renewable energy sources. Up to 54% of our study area was predicted to be unsuitable as Whooping Crane stopover habitat and could be considered relatively low risk for conflicts between Whooping Cranes and wind energy development. We suggest that this type of analysis be incorporated into the habitat conservation planning process in areas where incidental take permits are being considered for Whooping Cranes or other species of concern. Field surveys should always be conducted prior to construction to verify model predictions and understand baseline conditions.

  5. Effects of 20 Selected Fruits on Ethanol Metabolism: Potential Health Benefits and Harmful Impacts.

    Science.gov (United States)

    Zhang, Yu-Jie; Wang, Fang; Zhou, Yue; Li, Ya; Zhou, Tong; Zheng, Jie; Zhang, Jiao-Jiao; Li, Sha; Xu, Dong-Ping; Li, Hua-Bin

    2016-04-01

    The consumption of alcohol is often accompanied by other foods, such as fruits and vegetables. This study is aimed to investigate the effects of 20 selected fruits on ethanol metabolism to find out their potential health benefits and harmful impacts. The effects of the fruits on ethanol metabolism were characterized by the concentrations of ethanol and acetaldehyde in blood, as well as activities of alcohol dehydrogenase and acetaldehyde dehydrogenase in liver of mice. Furthermore, potential health benefits and harmful impacts of the fruits were evaluated by biochemical parameters including aspartate transaminase (AST), alanine transferase (ALT), malondialdehyde, and superoxide dismutase. Generally, effects of these fruits on ethanol metabolism were very different. Some fruits (such as Citrus limon (yellow), Averrhoa carambola, Pyrus spp., and Syzygium samarangense) could decrease the concentration of ethanol in blood. In addition, several fruits (such as Cucumis melo) showed hepatoprotective effects by significantly decreasing AST or ALT level in blood, while some fruits (such as Averrhoa carambola) showed adverse effects. The results suggested that the consumption of alcohol should not be accompanied by some fruits, and several fruits could be developed as functional foods for the prevention and treatment of hangover and alcohol use disorder.

  6. In vitro selection of bacteria with potential for use as probiotics in marine shrimp culture

    Directory of Open Access Journals (Sweden)

    Felipe do Nascimento Vieira

    2013-08-01

    Full Text Available The objective of this work was to isolate strains of lactic acid bacteria with probiotic potential from the digestive tract of marine shrimp (Litopenaeus vannamei, and to carry out in vitro selection based on multiple characters. The ideotype (ideal proposed strain was defined by the highest averages for the traits maximum growth velocity, final count of viable cells, and inhibition halo against nine freshwater and marine pathogens, and by the lowest averages for the traits duplication time and resistance of strains to NaCl (1.5 and 3%, pH (6, 8, and 9, and biliary salts (5%. Mahalanobis distance (D² was estimated among the evaluated strains, and the best ones were those with the shortest distances to the ideotype. Ten bacterial strains were isolated and biochemically identified as Lactobacillus plantarum (3, L. brevis (3, Weissella confusa (2, Lactococcus lactis (1, and L. delbrueckii (1. Lactobacillus plantarum strains showed a wide spectrum of action and the largest inhibition halos against pathogens, both Gram-positive and negative, high growth rate, and tolerance to all evaluated parameters. In relation to ideotype, L. plantarum showed the lowest Mahalanobis (D² distance, followed by the strains of W. confusa, L. brevis, L. lactis, and L. delbrueckii. Among the analyzed bacterial strains, those of Lactobacillus plantarum have the greatest potential for use as a probiotic for marine shrimp.

  7. Explore the Most Potential Supplier’s Selection Determinants in Modern Supply Chain Management

    Directory of Open Access Journals (Sweden)

    Ming-Yuan Hsieh

    2014-01-01

    Full Text Available To increment the research reliability, validity, and representativeness, this study creatively cross-employed the factor analysis (FA and the grey relational analysis (GRA methods. The results of the 144 fully completed questionnaires are analyzed by FA and then these results were utilized in second questionnaires design of 15 experts. Furthermore, the results of these second questionnaires were further analyzed by GRA in order to explore the most potential supplier’s selection determinants in the modern supply chain management (MSCM. Beyond a series of measurements, the measured results have induced three contributive findings: (1 the empirical interviewed industrialists reported concern that suppliers have to provide a higher material yield rate and material delivery on time rate for the qualitative increment as well as a higher supplier’s gross margin ROI for the financial stabilization in MSCM; (2 the 15 experts concluded that material insurance rate is an important attribute to estimate risky assessments and the supplier’s gross margin ROI and warehouse operations cost as a percentage of sales are critical elements in the financial evaluations of potential suppliers; and (3 Supplier’s gross margin ROI, outbound freight cost as a percentage of sales, and material insurance rate are the three most decisive determinants in MSCM.

  8. Effects of 20 Selected Fruits on Ethanol Metabolism: Potential Health Benefits and Harmful Impacts

    Science.gov (United States)

    Zhang, Yu-Jie; Wang, Fang; Zhou, Yue; Li, Ya; Zhou, Tong; Zheng, Jie; Zhang, Jiao-Jiao; Li, Sha; Xu, Dong-Ping; Li, Hua-Bin

    2016-01-01

    The consumption of alcohol is often accompanied by other foods, such as fruits and vegetables. This study is aimed to investigate the effects of 20 selected fruits on ethanol metabolism to find out their potential health benefits and harmful impacts. The effects of the fruits on ethanol metabolism were characterized by the concentrations of ethanol and acetaldehyde in blood, as well as activities of alcohol dehydrogenase and acetaldehyde dehydrogenase in liver of mice. Furthermore, potential health benefits and harmful impacts of the fruits were evaluated by biochemical parameters including aspartate transaminase (AST), alanine transferase (ALT), malondialdehyde, and superoxide dismutase. Generally, effects of these fruits on ethanol metabolism were very different. Some fruits (such as Citrus limon (yellow), Averrhoa carambola, Pyrus spp., and Syzygium samarangense) could decrease the concentration of ethanol in blood. In addition, several fruits (such as Cucumis melo) showed hepatoprotective effects by significantly decreasing AST or ALT level in blood, while some fruits (such as Averrhoa carambola) showed adverse effects. The results suggested that the consumption of alcohol should not be accompanied by some fruits, and several fruits could be developed as functional foods for the prevention and treatment of hangover and alcohol use disorder. PMID:27043608

  9. Screening of CHP Potential at Federal Sites in Select Regions of the U.S.

    Energy Technology Data Exchange (ETDEWEB)

    Energy Nexus Group, . .

    2002-02-25

    Combined Cooling Heat and Power (CHP) is a master term for onsite power generation technologies that sequentially produce electrical or mechanical energy and useful thermal energy. Some form of CHP has existed for more than 100 years and it is now achieving a greater level of acceptance due to an increasing need for reliable power service and energy cost management. Capturing and using the heat produced as a byproduct of generating electricity from fuel sources increases the usable energy that can be obtained from the original fuel source. CHP technologies have the potential to reduce energy consumption through increased efficiency--decreasing energy bills as well as pollution. The EPA recognizes CHP as a potent climate change mitigation measure. The U.S. Department of Energy (D.O.E.) Federal Energy Management Program (FEMP) is assisting Federal agencies to realize their energy efficiency goals. CHP is an efficiency measure that is receiving growing attention because of its sizable potential to provide efficiency, environmental, and reliability benefits. CHP therefore benefits the host facility, the electric infrastructure, and the U.S. society as a whole. This report and study seeks to make a preliminary inquiry into near term CHP opportunities for federal facilities in selected U.S. regions. It offers to help focus the attention of policy makers and energy facility managers on good candidate facilities for CHP. First, a ranked list of high potential individual sites is identified. Then, several classes of federal facilities are identified for the multiple opportunities they offer as a class. Recommendations are then offered for appropriate next steps for the evaluation and cost effective implementation of CHP. This study was designed to ultimately rank federal facilities in terms of their potential to take advantage of CHP economic and external savings in the near term. In order to best serve the purposes of this study, projections have been expressed in terms of

  10. Phenolic Profile and Antioxidant Potential of Leaves from Selected Cotoneaster Medik. Species

    Directory of Open Access Journals (Sweden)

    Agnieszka Kicel

    2016-05-01

    Full Text Available The antioxidant efficiency of 70% aqueous methanolic extracts from the leaves of twelve selected Cotoneaster Medik. species was evaluated using four complementary in vitro tests based on SET- (single electron transfer and HAT-type (hydrogen atom transfer mechanisms (DPPH, FRAP, O2•− and H2O2 scavenging assays. The samples exhibited the dose-dependent responses in all assays with activity parameters of EC50 = 18.5–34.5 µg/mL for DPPH; 0.9–3.8 mmol Fe2+/g for FRAP; SC50 = 27.7–74.8 µg/mL for O2•−; and SC50 = 29.0–91.3 µg/mL for H2O2. Significant linear correlations (|r| = 0.76–0.97, p < 0.01 between activity parameters and total contents of phenolics (5.2%–15.4% GAE and proanthocyanidins (2.1%–15.0% CYE, with weak or no effects for chlorogenic acid isomers (0.69%–2.93% and total flavonoids (0.28%–1.40% suggested that among the listed polyphenols, proanthocyanidins are the most important determinants of the tested activity. UHPLC-PDA-ESI-QTOF-MS analyses led to detection of 34 polyphenols, of which 10 B-type procyanidins, 5 caffeoylquinic acids and 14 flavonoids were identified. After cluster analysis of the data matrix, the leaves of Cotoneaster zabelii, C. splendens, C. bullatus, C. divaricatus, C. hjelmqvistii and C. lucidus were selected as the most promising sources of natural antioxidants, exhibiting the highest phenolic levels and antioxidant capacities, and therefore the greatest potential for pharmaceutical applications.

  11. A Study on the nature of genetic divergence in rice from assam and North East Himalayas.

    Science.gov (United States)

    Vairavan, S; Siddiq, E A; Arunachalam, V; Swaminathan, M S

    1973-01-01

    A representative group of 190 rice types collected from North-East India along with four standard varieties, three of which were indicas and one japonica, was studied to understand the nature of genetic divergence. Preliminary grouping was done by canonical analysis and the resultant 42 groups were further classified using the D(2) statistic.The final grouping resulted in nine divergent clusters. The three indica standards were found in three different clusters indicating the wide available variability among them. The japonica standard formed a separate group by itself. A majority of the North-East Indian types formed clusters with indicas, whereas some were intermediate and still others were closer to japonica or indica, thus indicating a series of intergrades bridging indica and japonica.Height followed by leaf area was found to be important for primary and 100-grain weight, followed by amylose content for secondary differentiation. It appears that natural selection as well as human selection might have operated for characters differentiating rice types in Assam and North Eastern Himalayas. Geographical distance was not found to be related to genetic divergence. The study suggests that O. sativa contains innumerable but divergent forms, and its classification into definite varietal groups on an arbitrary basis such as isolation barrier, sexual affinity or geographic distribution would be far from reality.

  12. High altitude survival: conflicts between pastoralism and wildlife in the Trans-Himalaya

    NARCIS (Netherlands)

    Mishra, C.

    2001-01-01

    Keywords : Pastoralism, agriculture, wildlife, Himalaya, competition, bharal, yak, livestock, snow leopard, wolf, herbivore, ungulate, resource, rangeland, steppe, mountainHow harmonious is the coexistence between pastoralism and wildlife? This thesis is a response to repeated calls for a better und

  13. Automated tube potential selection for standard chest and abdominal CT in follow-up patients with testicular cancer: comparison with fixed tube potential

    Energy Technology Data Exchange (ETDEWEB)

    Gnannt, Ralph; Winklehner, Anna; Frauenfelder, Thomas; Alkadhi, Hatem [University Hospital Zurich, Institute of Diagnostic and Interventional Radiology, Zurich (Switzerland); Eberli, Daniel [University Hospital Zurich, Clinic for Urology, Zurich (Switzerland); Knuth, Alexander [University Hospital Zurich, Clinic for Oncology, Zurich (Switzerland)

    2012-09-15

    To evaluate prospectively, in patients with testicular cancer, the radiation dose-saving potential and image quality of contrast-enhanced chest and abdominal CT with automated tube potential selection. Forty consecutive patients with testicular cancer underwent contrast-enhanced arterio-venous chest and portal-venous abdominal CT with automated tube potential selection (protocol B; tube potential 80-140 kVp), which is based on the attenuation of the CT topogram. All had a first CT at 120 kVp (protocol A) using the same 64-section CT machine and similar settings. Image quality was assessed; dose information (CTDI{sub vol}) was noted. Image noise and attenuation in the liver and spleen were significantly higher for protocol B (P < 0.05 each), whereas attenuation in the deltoid and erector spinae muscles was similar. In protocol B, tube potential was reduced to 100 kVp in 18 chest and 33 abdominal examinations, and to 80 kVp in 5 abdominal CT examinations; it increased to 140 kVp in one patient. Image quality of examinations using both CT protocols was rated as diagnostic. CTDI{sub vol} was significantly lower for protocol B compared to protocol A (reduction by 12%, P < 0.01). In patients with testicular cancer, radiation dose of chest and abdominal CT can be reduced with automated tube potential selection, while image quality is preserved. (orig.)

  14. Geophysical Characterization of the Salna Sinking Zone, Garhwal Himalaya, India

    Science.gov (United States)

    Sastry, Rambhatla G.; Mondal, Suman K.

    2013-01-01

    Infrastructure and communication facilities are repeatedly affected by ground deformation in Gharwal Himalaya, India; for effective remediation measures, a thorough understanding of the real reasons for these movements is needed. In this regard, we undertook an integrated geophysical and geotechnical study of the Salna sinking zone close to the Main Central Thrust in Garhwal Himalaya. Our geophysical data include eight combined electrical resistivity tomography (ERT) and induced polarization imaging (IPI) profiles spanning 144-600 m, with 3-10 m electrode separation in the Wenner-Schlumberger configuration, and five micro-gravity profiles with 10-30 m station spacing covering the study region. The ERT sections clearly outline the heterogeneity in the subsurface lithology. Further, the ERT, IPI, and shaliness (shaleyness) sections infer the absence of clayey horizons and slip surfaces at depth. However, the Bouguer gravity analysis has revealed the existence of several faults in the subsurface, much beyond the reach of the majority of ERT sections. These inferred vertical to subvertical faults run parallel to the existing major lineaments and tectonic elements of the study region. The crisscross network of inferred faults has divided the entire study region into several blocks in the subsurface. Our studies stress that the sinking of the Salna village area is presently taking place along these inferred vertical to subvertical faults. The Chamoli earthquake in March 1999 probably triggered seismically induced ground movements in this region. The absence of few gravity-inferred faults in shallow ERT sections may hint at blind faults, which could serve as future source(s) for geohazards in the study region. Soil samples at two sites of study region were studied in a geotechnical laboratory. These, along with stability studies along four slope sections, have indicated the critical state of the study region. Thus, our integrated studies emphasize the crucial role of

  15. The genus Chaerilus Simon, 1877 (Scorpiones, Chaerilidae in the Himalayas and description of a new species

    Directory of Open Access Journals (Sweden)

    Wilson Lourenco

    2010-02-01

    Full Text Available A new species is described belonging to the genus Chaerilus Simon, 1877. Chaerilus annapurna sp. n. was discovered in the high plateaux of the Himalayas in Central-Western Nepal. For comparative purposes a precise re-diagnosis is proposed for Chaerilus truncatus Karsch, 1879, originally described from an imprecise locality in Himalaya. This species has recently been discussed by several authors: nevertheless, it has sometimes been the subject of misidentification.

  16. Glacial Lake Expansion in the Central Himalayas by Landsat Images, 1990–2010

    OpenAIRE

    Yong Nie; Qiao Liu; Shiyin Liu

    2013-01-01

    Glacial lake outburst flood (GLOF) is a serious hazard in high, mountainous regions. In the Himalayas, catastrophic risks of GLOFs have increased in recent years because most Himalayan glaciers have experienced remarkable downwasting under a warming climate. However, current knowledge about the distribution and recent changes in glacial lakes within the central Himalaya mountain range is still limited. Here, we conducted a systematic investigation of the glacial lakes within the entire centra...

  17. Changes in Rongbuk lake and Imja lake in the Everest region of Himalaya

    OpenAIRE

    Chen, W.; T. Doko; Liu, C.; Ichinose, T.; Fukui, H.; Feng, Q.; Gou, P.

    2014-01-01

    The Himalaya holds the world record in terms of range and elevation. It is one of the most extensively glacierized regions in the world except the Polar Regions. The Himalaya is a region sensitive to climate change. Changes in the glacial regime are indicators of global climate changes. Since the second half of the last century, most Himalayan glaciers have melted due to climate change. These changes directly affected the changes of glacial lakes in the Himalayan region due to the gl...

  18. Emergency water supply: a review of potential technologies and selection criteria.

    Science.gov (United States)

    Loo, Siew-Leng; Fane, Anthony G; Krantz, William B; Lim, Teik-Thye

    2012-06-15

    Access to safe drinking water is one of the first priorities following a disaster. However, providing drinking water to the affected population (AP) is challenging due to severe contamination and lack of access to infrastructure. An onsite treatment system for the AP is a more sustainable solution than transporting bottled water. Emergency water technologies (WTs) that are modular, mobile or portable are suitable for emergency relief. This paper reviews WTs including membrane technologies that are suitable for use in emergencies. Physical, chemical, thermal- and light-based treatment methods, and membrane technologies driven by different driving forces such as pressure, temperature and osmotic gradients are reviewed. Each WT is evaluated by ten mutually independent criteria: costs, ease of deployment, ease of use, maintenance, performance, potential acceptance, energy requirements, supply chain requirements, throughput and environmental impact. A scoring system based on these criteria is presented. A methodology for emergency WT selection based on compensatory multi-criteria analysis is developed and discussed. Finally, critical research needs are identified.

  19. Dispersal syndrome differentiation of Pinus armandii in Southwest China: Key elements of a potential selection mosaic

    Science.gov (United States)

    Chen, Fan; Chen, Jin

    2011-11-01

    Pinus armandii is a species of pine native to China with a wide geographical distribution and large-wingless seeds (about 300 mg). The study is to determine the variation in seed dispersal traits among populations within a relative small geographic scale and furthermore to explore if the trait differentiation results in the differences in dispersers, in particular nutcrackers ( Nucifraga caryocatactes) and scatter-hoarding rodents. We conducted studies at five sites at different elevations in northwest Yunnan Province. The study sites are separated by 10-200 km and divided into populations partly isolated by mountains and rivers. The cone and seed traits diverged significantly among the five study sites while the traits among individual trees at each site did not differ significantly. Nutcrackers and scatter-hoarding rodents presented conflicting preference in cone and seed traits: nutcrackers preferred smaller cones with smaller seeds, which increased the foraging efficiency of nutcrackers; while scatter-hoarding rodents tended to cache larger seeds. Consistent with variation in preferences by nutcrackers and scatter-hoarding rodents, in nutcracker-dominated sites, pines were characterized by smaller cones, smaller seeds, and thinner seed coats; while in sites where nutcrackers were not abundant, pines had relatively larger cones with larger seeds, which could enhance caching activities by scatter-hoarding rodents. The study provided some key elements for potential selection mosaic on cone and seed traits of a long-lived perennial tree among populations with limited geographical range.

  20. PRODUCTION POTENTIALS AND THE PHYSICOCHEMICAL COMPOSITION OF SELECTED DUCK STRAINS: A MINI REVIEW

    Directory of Open Access Journals (Sweden)

    FREDERICK ADZITEY

    2012-01-01

    Full Text Available Physicochemical composition of meat is an important factor in human nutrition and contributes to the choice of food by mankind. In recent times humans are much conscious of the health benefits of what they consume. Emphasize on the consumption of balance diets have been given much attention. The consumption of organic foods, vegetables, fruits, foods high in fibre, foods of animal origin with less fat and cholesterol are among the food stuffs being upheld. Poultry meat, eggs and products are widely consumed worldwide without much religious restrictions. The high consumption of poultry meat is partly due to it ease for preparing different dishes and the development of a wide range of processed ready-to-eat meals incorporated with chicken as a major protein source. Poultry meat (white meat is known to be healthier than red meat probably due to its low calorie and lipid contents. Duck meat is comparable to that of chicken despite being red meat and it is a close alternative source of protein and other nutrients for humans. Duck meat is high in protein, iron, selenium and niacin; and lower in calories compared to many cuts of beef. This mini-review reports on the production potentials of ducks and the physicochemical composition of selected duck strains. It also reports on world duck population.

  1. Selection of a mineral binder with potentialities for the stabilization/solidification of aluminum metal

    Energy Technology Data Exchange (ETDEWEB)

    Cau Dit Coumes, C., E-mail: celine.cau-dit-coumes@cea.fr [Commissariat à l’Energie Atomique et aux Energies Alternatives, CEA/DEN/MAR/DTCD/SPDE, BP17171, 30207 Bagnols-sur-Cèze cedex (France); Lambertin, D.; Lahalle, H.; Antonucci, P. [Commissariat à l’Energie Atomique et aux Energies Alternatives, CEA/DEN/MAR/DTCD/SPDE, BP17171, 30207 Bagnols-sur-Cèze cedex (France); Cannes, C.; Delpech, S. [Institut de Physique Nucléaire, CNRS, Univ. Paris-Sud 11, 91406 Orsay Cedex (France)

    2014-10-15

    Highlights: • Binders capable of reducing the pore solution pH compared with Portland cements are reviewed. • The binders are then tested against aluminum corrosion. • Corrosion of aluminum metal is minimal with magnesium phosphate cement. • The H{sub 2} release can be reduced still further by adding LiNO{sub 3} to the mixing solution. • Electrochemical characterizations show that aluminum tends to a passive state. - Abstract: In a strongly alkaline medium, such as that encountered in conventional cementitious materials based on Portland cement, aluminum metal is corroded, with continued production of hydrogen. In order to develop a mineral matrix having enhanced compatibility with aluminum, a literature review was first undertaken to identify binders capable of reducing the pore solution pH compared with Portland cement. An experimental study was then carried out to measure the hydrogen production resulting from corrosion of aluminum metal rods encapsulated in the different selected cement pastes. The best results were achieved with magnesium phosphate cement, which released very little hydrogen over the duration of the study. This production could be reduced still further by adding a corrosion inhibitor (lithium nitrate) to the mixing solution. Open circuit potential measurement and Electrochemical Impedance Spectroscopy of aluminum electrode encapsulated in two pastes based on Portland cement and magnesium phosphate cement showed different redox behaviors. In the Portland cement paste, the electrochemical data confirmed the corrosion of aluminum whereas this latter tended to a passive state in the magnesium phosphate binder.

  2. Selection of a mineral binder with potentialities for the stabilization/solidification of aluminum metal

    Science.gov (United States)

    Cau Dit Coumes, C.; Lambertin, D.; Lahalle, H.; Antonucci, P.; Cannes, C.; Delpech, S.

    2014-10-01

    In a strongly alkaline medium, such as that encountered in conventional cementitious materials based on Portland cement, aluminum metal is corroded, with continued production of hydrogen. In order to develop a mineral matrix having enhanced compatibility with aluminum, a literature review was first undertaken to identify binders capable of reducing the pore solution pH compared with Portland cement. An experimental study was then carried out to measure the hydrogen production resulting from corrosion of aluminum metal rods encapsulated in the different selected cement pastes. The best results were achieved with magnesium phosphate cement, which released very little hydrogen over the duration of the study. This production could be reduced still further by adding a corrosion inhibitor (lithium nitrate) to the mixing solution. Open circuit potential measurement and Electrochemical Impedance Spectroscopy of aluminum electrode encapsulated in two pastes based on Portland cement and magnesium phosphate cement showed different redox behaviors. In the Portland cement paste, the electrochemical data confirmed the corrosion of aluminum whereas this latter tended to a passive state in the magnesium phosphate binder.

  3. Wind potential assessment to estimate performance of selected wind turbines in Pandansimo Beach-Yogyakarta

    Science.gov (United States)

    Tjahjana, D. D. D. P.; Al-Masuun, I. K.; Gustiantono, A.

    2016-03-01

    This paper presents the characteristics of wind speed and wind energy potential in the Pandansimo Beach-Yogyakarta based on Weibull distribution analysis. Ten-min average time series wind-speed data for a period of 2 year, measured at a height 50 m, are used in this study. The continuously recorded wind speed data were averaged over 10 minutes and stored in data logger. The results showed that the annual mean wind speed at location is 6.249 m/s, while the annual mean power densities is 264 W/m². It was further shown that the mean annual value of the most probable wind speed is 5.5 m/s and the mean annual value of the wind speed carrying maximum energy is 9.608 m/s. The performance of selected commercial wind turbine models designed for electricity generation in the site was examined. The wind turbine with the highest value of capacity factor is VESTAS V-110 with 33.97% and can produce 5951.04 M Wh/year.

  4. Therapeutic potential of functional selectivity in the treatment of heart failure

    DEFF Research Database (Denmark)

    Christensen, Gitte Lund; Aplin, Mark; Hansen, Jakob Lerche

    2010-01-01

    to design ligands with "functional selectivity," acting as agonists on certain signaling pathways while antagonizing others. This represents a major pharmaceutical opportunity to separate desired from adverse effects governed by the same receptor. Accordingly, functionally selective ligands are currently...

  5. Oligocene crustal anatexis in the Tethyan Himalaya, southern Tibet

    Science.gov (United States)

    Gao, Li-E.; Zeng, Lingsen; Gao, Jiahao; Shang, Zhen; Hou, Kejun; Wang, Qian

    2016-11-01

    Recent studies in the Xiaru and Malashan gneiss dome of the Tethyan Himalaya, southern Tibet identify that Xiaru and Paiku tourmaline-bearing leucogranite dike formed at 28-29 Ma. Together with 28 Ma Kuday garnet-bearing leucogranites, it is demonstrated that the Himalayan orogenic belt experienced a major episode of crustal melting in the Mid-Oligocene. Geochemical data indicate that three suites of leucogranite are characterized by large variations in the major and trace element compositions as well as Sr-Nd isotope systematics, which could be explained by combined fractional crystallization and relative contributions of micas and accessory phases dissolved into a crustal melt during decompressional melting of metapelitic rocks. Documentation of Oligocene partial melting of crustal rocks could indicate that the exhumation of deep crustal rocks in the Himalayan orogenic belt could have started as early as Oligocene.

  6. Atmospheric Modelling for Air Quality Study over the complex Himalayas

    Science.gov (United States)

    Surapipith, Vanisa; Panday, Arnico; Mukherji, Aditi; Banmali Pradhan, Bidya; Blumer, Sandro

    2014-05-01

    An Atmospheric Modelling System has been set up at International Centre for Integrated Mountain Development (ICIMOD) for the assessment of Air Quality across the Himalaya mountain ranges. The Weather Research and Forecasting (WRF) model version 3.5 has been implemented over the regional domain, stretching across 4995 x 4455 km2 centred at Ichhyakamana , the ICIMOD newly setting-up mountain-peak station (1860 m) in central Nepal, and covering terrains from sea-level to the Everest (8848 m). Simulation is carried out for the winter time period, i.e. December 2012 to February 2013, when there was an intensive field campaign SusKat, where at least 7 super stations were collecting meteorology and chemical parameters on various sites. The very complex terrain requires a high horizontal resolution (1 × 1 km2), which is achieved by nesting the domain of interest, e.g. Kathmandu Valley, into 3 coarser ones (27, 9, 3 km resolution). Model validation is performed against the field data as well as satellite data, and the challenge of capturing the necessary atmospheric processes is discussed, before moving forward with the fully coupled chemistry module (WRF-Chem), having local and regional emission databases as input. The effort aims at finding a better understanding of the atmospheric processes and air quality impact on the mountain population, as well as the impact of the long-range transport, particularly of Black Carbon aerosol deposition, to the radiative budget over the Himalayan glaciers. The higher rate of snowcap melting, and shrinkage of permafrost as noticed by glaciologists is a concern. Better prediction will supply crucial information to form the proper mitigation and adaptation strategies for saving people lives across the Himalayas in the changing climate.

  7. The Himalayas: barrier and conduit for gene flow.

    Science.gov (United States)

    Gayden, Tenzin; Perez, Annabel; Persad, Patrice J; Bukhari, Areej; Chennakrishnaiah, Shilpa; Simms, Tanya; Maloney, Trisha; Rodriguez, Kristina; Herrera, Rene J

    2013-06-01

    The Himalayan mountain range is strategically located at the crossroads of the major cultural centers in Asia, the Middle East and Europe. Although previous Y-chromosome studies indicate that the Himalayas served as a natural barrier for gene flow from the south to the Tibetan plateau, this region is believed to have played an important role as a corridor for human migrations between East and West Eurasia along the ancient Silk Road. To evaluate the effects of the Himalayan mountain range in shaping the maternal lineages of populations residing on either side of the cordillera, we analyzed mitochondrial DNA variation in 344 samples from three Nepalese collections (Newar, Kathmandu and Tamang) and a general population of Tibet. Our results revealed a predominantly East Asian-specific component in Tibet and Tamang, whereas Newar and Kathmandu are both characterized by a combination of East and South Central Asian lineages. Interestingly, Newar and Kathmandu harbor several deep-rooted Indian lineages, including M2, R5, and U2, whose coalescent times from this study (U2, >40 kya) and previous reports (M2 and R5, >50 kya) suggest that Nepal was inhabited during the initial peopling of South Central Asia. Comparisons with our previous Y-chromosome data indicate sex-biased migrations in Tamang and a founder effect and/or genetic drift in Tamang and Newar. Altogether, our results confirm that while the Himalayas acted as a geographic barrier for human movement from the Indian subcontinent to the Tibetan highland, it also served as a conduit for gene flow between Central and East Asia.

  8. Quantifying sources, transport, deposition, and radiative forcing of black carbon over the Himalayas and Tibetan Plateau

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Rudong; Wang, Hailong; Qian, Yun; Rasch, Philip J.; Easter, Richard C.; Ma, Po-Lun; Singh, Balwinder; Huang, Jianping; Fu, Qiang

    2015-01-01

    Black carbon (BC)particles over the Himalayas and Tibetan Plateau (HTP), both airborne and those deposited on snow, have been shown to affect snowmelt and glacier retreat. Since BC over the HTP may originate from a variety of geographical regions and emission sectors, it is essential to quantify the source-receptor relationships of BC in order to understand the contributions of natural and anthropogenic emissions and provide guidance for potential mitigation actions. In this study, we use the Community Atmosphere Model version 5 (CAM5) with a newly developed source tagging technique, nudged towards the MERRA meteorological reanalysis, to characterize the fate of BC particles emitted from various geographical regions and sectors. Evaluated against observations over the HTP and surrounding regions, the model simulation shows a good agreement in the seasonal variation of the near-surface airborne BC concentrations, providing confidence to use this modeling framework for characterizing BC source- receptor relationships. Our analysis shows that the relative contributions from different geographical regions and source sectors depend on seasons and the locations in the HTP. The largest contribution to annual mean BC burden and surface deposition in the entire HTP region is from biofuel and biomass (BB) emissions in South Asia, followed by fossil fuel (FF) emissions from South Asia, then FF from East Asia. The same roles hold for all the seasonal means except for the summer when East Asia FF becomes more important. For finer receptor regions of interest, South Asia BB and FF have the largest impact on BC in Himalayas and Central Tibetan Plateau, while East Asia FF and BB contribute the most to Northeast Plateau in all seasons and Southeast Plateau in the summer. Central Asia and Middle East FF emissions have relatively more important contributions to BC reaching Northwest Plateau, especially in the summer. Although the HTP local emissions only contribute about 10% of BC in

  9. Cluster analysis for identifying sub-groups and selecting potential discriminatory variables in human encephalitis

    Directory of Open Access Journals (Sweden)

    Crowcroft Natasha S

    2010-12-01

    Full Text Available Abstract Background Encephalitis is an acute clinical syndrome of the central nervous system (CNS, often associated with fatal outcome or permanent damage, including cognitive and behavioural impairment, affective disorders and epileptic seizures. Infection of the central nervous system is considered to be a major cause of encephalitis and more than 100 different pathogens have been recognized as causative agents. However, a large proportion of cases have unknown disease etiology. Methods We perform hierarchical cluster analysis on a multicenter England encephalitis data set with the aim of identifying sub-groups in human encephalitis. We use the simple matching similarity measure which is appropriate for binary data sets and performed variable selection using cluster heatmaps. We also use heatmaps to visually assess underlying patterns in the data, identify the main clinical and laboratory features and identify potential risk factors associated with encephalitis. Results Our results identified fever, personality and behavioural change, headache and lethargy as the main characteristics of encephalitis. Diagnostic variables such as brain scan and measurements from cerebrospinal fluids are also identified as main indicators of encephalitis. Our analysis revealed six major clusters in the England encephalitis data set. However, marked within-cluster heterogeneity is observed in some of the big clusters indicating possible sub-groups. Overall, the results show that patients are clustered according to symptom and diagnostic variables rather than causal agents. Exposure variables such as recent infection, sick person contact and animal contact have been identified as potential risk factors. Conclusions It is in general assumed and is a common practice to group encephalitis cases according to disease etiology. However, our results indicate that patients are clustered with respect to mainly symptom and diagnostic variables rather than causal agents

  10. Potential sources of analytical bias and error in selected trace element data-quality analyses

    Science.gov (United States)

    Paul, Angela P.; Garbarino, John R.; Olsen, Lisa D.; Rosen, Michael R.; Mebane, Christopher A.; Struzeski, Tedmund M.

    2016-09-28

    Potential sources of analytical bias and error associated with laboratory analyses for selected trace elements where concentrations were greater in filtered samples than in paired unfiltered samples were evaluated by U.S. Geological Survey (USGS) Water Quality Specialists in collaboration with the USGS National Water Quality Laboratory (NWQL) and the Branch of Quality Systems (BQS).Causes for trace-element concentrations in filtered samples to exceed those in associated unfiltered samples have been attributed to variability in analytical measurements, analytical bias, sample contamination either in the field or laboratory, and (or) sample-matrix chemistry. These issues have not only been attributed to data generated by the USGS NWQL but have been observed in data generated by other laboratories. This study continues the evaluation of potential analytical bias and error resulting from matrix chemistry and instrument variability by evaluating the performance of seven selected trace elements in paired filtered and unfiltered surface-water and groundwater samples collected from 23 sampling sites of varying chemistries from six States, matrix spike recoveries, and standard reference materials.Filtered and unfiltered samples have been routinely analyzed on separate inductively coupled plasma-mass spectrometry instruments. Unfiltered samples are treated with hydrochloric acid (HCl) during an in-bottle digestion procedure; filtered samples are not routinely treated with HCl as part of the laboratory analytical procedure. To evaluate the influence of HCl on different sample matrices, an aliquot of the filtered samples was treated with HCl. The addition of HCl did little to differentiate the analytical results between filtered samples treated with HCl from those samples left untreated; however, there was a small, but noticeable, decrease in the number of instances where a particular trace-element concentration was greater in a filtered sample than in the associated

  11. Herbal medicinals: selected clinical considerations focusing on known or potential drug-herb interactions.

    Science.gov (United States)

    Miller, L G

    1998-11-09

    Herbal medicinals are being used by an increasing number of patients who typically do not advise their clinicians of concomitant use. Known or potential drug-herb interactions exist and should be screened for. If used beyond 8 weeks, Echinacea could cause hepatotoxicity and therefore should not be used with other known hepatoxic drugs, such as anabolic steroids, amiodarone, methotrexate, and ketoconazole. However, Echinacea lacks the 1,2 saturated necrine ring associated with hepatoxicity of pyrrolizidine alkaloids. Nonsteroidal anti-inflammatory drugs may negate the usefulness of feverfew in the treatment of migraine headaches. Feverfew, garlic, Ginkgo, ginger, and ginseng may alter bleeding time and should not be used concomitantly with warfarin sodium. Additionally, ginseng may cause headache, tremulousness, and manic episodes in patients treated with phenelzine sulfate. Ginseng should also not be used with estrogens or corticosteroids because of possible additive effects. Since the mechanism of action of St John wort is uncertain, concomitant use with monoamine oxidase inhibitors and selective serotonin reuptake inhibitors is ill advised. Valerian should not be used concomitantly with barbiturates because excessive sedation may occur. Kyushin, licorice, plantain, uzara root, hawthorn, and ginseng may interfere with either digoxin pharmacodynamically or with digoxin monitoring. Evening primrose oil and borage should not be used with anticonvulsants because they may lower the seizure threshold. Shankapulshpi, an Ayurvedic preparation, may decrease phenytoin levels as well as diminish drug efficacy. Kava when used with alprazolam has resulted in coma. Immunostimulants (eg, Echinacea and zinc) should not be given with immunosuppressants (eg, corticosteroids and cyclosporine). Tannic acids present in some herbs (eg, St John wort and saw palmetto) may inhibit the absorption of iron. Kelp as a source of iodine may interfere with thyroid replacement therapies. Licorice

  12. Selective inhibition of RNA polymerase I transcription as a potential approach to treat African trypanosomiasis

    Science.gov (United States)

    Kerry, Louise E.; Pegg, Elaine E.; Cameron, Donald P.; Budzak, James; Poortinga, Gretchen; Hannan, Katherine M.; Hannan, Ross D.

    2017-01-01

    Trypanosoma brucei relies on an essential Variant Surface Glycoprotein (VSG) coat for survival in the mammalian bloodstream. High VSG expression within an expression site body (ESB) is mediated by RNA polymerase I (Pol I), which in other eukaryotes exclusively transcribes ribosomal RNA genes (rDNA). As T. brucei is reliant on Pol I for VSG transcription, we investigated Pol I transcription inhibitors for selective anti-trypanosomal activity. The Pol I inhibitors quarfloxin (CX-3543), CX-5461, and BMH-21 are currently under investigation for treating cancer, as rapidly dividing cancer cells are particularly dependent on high levels of Pol I transcription compared with nontransformed cells. In T. brucei all three Pol I inhibitors have IC50 concentrations for cell proliferation in the nanomolar range: quarfloxin (155 nM), CX-5461 (279 nM) or BMH-21 (134 nM) compared with IC50 concentrations in the MCF10A human breast epithelial cell line (4.44 μM, 6.89 μM or 460 nM, respectively). T. brucei was therefore 29-fold more sensitive to quarfloxin, 25-fold more sensitive to CX-5461 and 3.4-fold more sensitive to BMH-21. Cell death in T. brucei was due to rapid inhibition of Pol I transcription, as within 15 minutes treatment with the inhibitors rRNA precursor transcript was reduced 97-98% and VSG precursor transcript 91-94%. Incubation with Pol I transcription inhibitors also resulted in disintegration of the ESB as well as the nucleolus subnuclear structures, within one hour. Rapid ESB loss following the block in Pol I transcription argues that the ESB is a Pol I transcription nucleated structure, similar to the nucleolus. In addition to providing insight into Pol I transcription and ES control, Pol I transcription inhibitors potentially also provide new approaches to treat trypanosomiasis. PMID:28263991

  13. Back-thrusting in Lesser Himalaya: Evidences from magnetic fabric studies in parts of Almora crystalline zone, Kumaun Lesser Himalaya

    Indian Academy of Sciences (India)

    Amar Agarwal; K K K K Agarwal; R Bali; Chandra Prakash; Gaurav Joshi

    2016-06-01

    The present study aims to understand evolution of the Lesser Himalaya, which consists of (meta) sedimentaryand crystalline rocks. Field studies, microscopic and rock magnetic investigations have beencarried out on the rocks near the South Almora Thrust (SAT) and the North Almora Thrust (NAT),which separates the Almora Crystalline Zone (ACZ) from the Lesser Himalayan sequences (LHS). Theresults show that along the South Almora Thrust, the deformation is persistent; however, near theNAT deformation pattern is complex and implies overprinting of original shear sense by a youngerdeformational event. We attribute this overprinting to late stage back-thrusting along NAT, active afterthe emplacement of ACZ. During this late stage back-thrusting, rocks of the ACZ and LHS were coupled.Back-thrusts originated below the Lesser Himalayan rocks, probably from the Main Boundary Thrust,and propagated across the sedimentary and crystalline rocks. This study provides new results frommultiple investigations, and enhances our understanding of the evolution of the ACZ.

  14. Soil quality index as affected by different cropping systems in northwestern Himalayas.

    Science.gov (United States)

    Sofi, J A; Bhat, A G; Kirmai, N A; Wani, J A; Lone, Aabid H; Ganie, Mumtaz A; Dar, G I H

    2016-03-01

    Soil quality assessment provides a tool for evaluating the sustainability of soils under different crop cafeterias. Our objective was to develop the soil quality index for evaluating the soil quality indicators under different cropping systems in northwest Himalaya-India. Composite soil samples were taken from the study area from different cropping systems which include T1 (forest soil control), T2 (rice-oilseed, lower belts), T3 (rice-oilseed, higher belts), T4 (rice-oats), T5 (rice-fallow), T6 (maize-oats), T7 (maize-peas), T8 (apple), T9 (apple-beans), and T10 (apple-maize). Physical, chemical, and biological soil indicators were determined, and it was found that soil enzyme activities involved in nutrient cycling were significantly higher in forest soils, which were reflected in higher levels of available pool of nutrients. Carbon stocks were found significantly higher in forest soil which was translated in improved soil physical condition. Principal component analysis (PCA) was performed to reduce multidimensionality of data followed by scoring by homothetic transformation of the selected indicators. Pearson's interclass correlation was performed to avoid redundancy, and highly correlated variables were not retained. Inclusion of legumes in the apple orchard floor recorded highest soil quality rating across the treatments. Cereal-based cropping systems were found in lower soil quality rating; however, the incorporation of peas in the system improved soil health.

  15. Brief Communication: Contending estimates of early 21st century glacier mass balance over the Pamir-Karakoram-Himalaya

    Directory of Open Access Journals (Sweden)

    A. Kääb

    2014-11-01

    Full Text Available We present glacier thickness changes over the entire Pamir-Karakoram-Himalaya arc based on ICESat satellite altimetry data for 2003–2008. The strongest thinning (−1 is observed for the East Nyainqêntanglha Shan. Conversely, glaciers of the West Kunlun Shan are slightly gaining volume, and Pamir and Karakoram seem to be on the western edge of an anomaly rather than its centre. For the Ganges, Indus and Brahmaputra basins, the glacier mass change reaches −22 ± 3 Gt yr−1, about 10% of the current glacier contribution to sea-level rise. For selected catchments over the study area we estimate glacier imbalance contributions to river runoff from a few percent to far over 10%. We highlight the importance of C-band penetration for studies based on the SRTM elevation model. To the very east and west of our study area, this penetration seems to be of larger magnitude and variability than previously assumed.

  16. Large landslides lie low: Vertical domains of denudation processes in the arid Himalaya-Karakoram orogen

    Science.gov (United States)

    Blöthe, Jan Henrik

    2014-05-01

    Large bedrock landslides (defined here as affecting >0.1 km2 in planform area) are thought to substantially contribute to denuding active mountain belts, and limiting the growth of topographic relief produced by concurrent tectonic uplift and fluvial or glacial incision. While most research on large landslides has focused on tectonically active, humid mountain belts with varying degrees of rainstorm and earthquake activity, lesser attention has been devoted to arid mountain belts. Especially in the Himalaya, where high denudation rates are commonly associated with high landslide activity, previous work has largely ignored landslide processes in the arid compartments of the orogen. This was motivation for us to compile a landslide inventory covering the arid Himalaya-Karakoram of NW India and N Pakistan within the Indus catchment. Our data set contains 493 rock-slope failures that we compiled from published studies and mapping from remote sensing imagery. Using an empirical volume-area scaling approach we estimate the total landslide volume at >250 km3. This is more than thousand times the contemporary annual sediment load in the Indus River. We analyse the distribution of these volumetrically significant landslides with respect to the regional hypsometry, contemporary glacier cover, and the distribution of rock glaciers. We find that large bedrock landslides in the arid Himalaya-Karakoram region preferentially detach near or from below the study area's median elevation, while glaciers and rock glaciers occupy higher elevations almost exclusively. This trend holds true for both the study area and parts thereof. The largest and highest-lying landslides occur in the Karakoram mountains, where local relief exceeds 6 km, and >90% of the landslide areas lie below the region's median elevation. Our analysis reveals a hitherto unrecognized vertical layering of denudation processes, with landslides chiefly operating below the median elevation, whereas mass transport by

  17. Magnetostratigraphy of the Neogene Siwalik Group of far eastern Himalaya, Kameng section, Arunashal Pradesh, India

    Science.gov (United States)

    Chirouze, Francois; Huyghe, Pascale; Dupont-Nivet, Guillaume

    2010-05-01

    Foreland basins act as receptacles for synorogenic sediments and store materials eroded off a convergent mountain belt (DeCelles and Giles, 1996, DeCelles and Giles, 1996). Their infill records tectonic, climatic and erosional processes that govern the development of the mountain belt and the foreland basin. Consequently, studying the infill of foreland basins can give clues as to the reconstruction of the orogen tectonic growth and the interaction with global or regional climate (e.g. Molnar & England, 1990). The Himalaya, the highest range in the world, is used as a natural laboratory to test the interactions between these processes, in particular because of the effect of the Tibetan Plateau uplift on the intensity and variability of the Asian monsoon (Kutzbach et al., 1993; Fluteau et al., 1999). Exhumation, erosion and climate events affecting the Himalaya are recorded in the Neogene Siwalik foreland basin deposits (e.g. DeCelles et al., 1998, 2000; Galy et al., 1999; Huyghe et al., 2001, 2005; Najman, 2005). Dating these deposits is a key element to reconstruct the Himalaya's evolution. Despite a wealth of studies in the central and western Himalayan foreland, very few studies have been carried out in the eastern part (Yin et al., 2006, Cina et al 2009). Understanding the evolution of this eastern part is essential for reconstructing the regional migration of the Himalayan deformation. In addition, the eastern Himalayan foreland potentially records the evolution of processes associated to the eastern syntaxis drainage networks (Singh and France-Lanord, 2002) and the Shillong plateau uplift (Grujic et al., 2006). Therefore, accurate dating of the sediments of the Eastern part of the Siwalik foreland basin using magnetostratigraphy is a crucial initial step for further investigations such as sedimentological and structural field studies, fission tracks, provenance and isotopic stable laboratory analysis. These investigations aim at constraining the exhumation

  18. Preliminary assessment of active rock slope instabilities in the high Himalaya of Bhutan

    Science.gov (United States)

    Dini, Benedetta; Manconi, Andrea; Leith, Kerry; Loew, Simon

    2016-04-01

    The small kingdom of Bhutan, nested between India and Tibet (between 88° and 92° east and 26° and 28° north), is characterised by markedly different landscapes and climatic zones. V-shaped, forest-covered valleys in the south, affected by the monsoonal rains, give gradually way to steep, barren slopes of U-shaped valleys in the drier north, host of the highest peaks, a large number of glaciers and glacial lakes. A transition zone of vegetated, elevated plateaus collects the towns in which most of the population lives. Landslides in the high Himalaya of Bhutan have not been extensively studied despite the primary and secondary hazards related to them. The regulations and restrictions to travel to and within Bhutan imposed by the government, as well as the extremely rugged terrain hinder the accessibility to remote slopes and valleys, both of which have resulted in lack of data and investigations. In this work, we aim at producing an inventory of large rock slope instabilities (> 1 million m3) across the high Himalaya of Bhutan, identifying types of failure, assessing the activity and analysing the distribution of landslides in combination with predisposing and preparatory factors, such as lithology, tectonic structures, hypsometry, deglaciation, fluvial erosive power and climate. At this stage, we rely on the information retrieved through satellite remote sensing data, i.e. medium and high resolution DEMs, optical images and space borne Synthetic Aperture Radar (SAR) data. An initial inventory was compiled based on the identification of geomorphological features associated with slope instabilities using the available Google Earth images. Moreover, we assessed the SAR data coverage and the expected geometrical distortions by assuming different sensors (ERS, Envisat, and ALOS Palsar-1). As we are mainly interested in detecting the surface deformation related to large unstable slopes by applying Differential SAR, we also computed the percentage of potentially

  19. Erodibility controls on the vertical and horizontal scalings of topography : a case study in the Himalayas

    Science.gov (United States)

    Godard, V.; Steer, P.

    2011-12-01

    Understanding the scaling properties of topography in actively uplifting areas is a major issue in quantitative geomorphology. Analytical formulations of non-glaciated landscape evolution clearly demonstrate that metrics such as local relief or drainage density are explicitly related to the spatial distribution of tectonic uplift, precipitation, erodibility and local slope across the landscape. However, in most regions, these parameters are seldom documented with enough resolution and precision to allow a systematic and statistically significant investigation of their relationships with both horizontal and vertical scaling properties of topography. A notable exception is the Himalaya of central Nepal, where the last 20 years of tectonic and geomorphological research have produced one of the densest regional data-set and documented major gradients in uplift and precipitation across the range [e.g. Lavé and Avouac, 2001; Bookhagen and Burbank, 2006]. The purpose of our study is to use this data in order to develop a detailed investigation of the influence of the erodibility parameter in controlling the structure and texture of the landscape. We first build on the derivation of total catchment relief of Tucker and Whipple [2002] to include the contribution of precipitation in addition to uplift, erodibility. Then, by minimizing the misfit between observed and predicted catchment relief, we assess the erodibility parameter for each second or third order catchment in our area of investigation. The resultant erodibility map (1) matches the distribution of geological units and (2) reveals a number of interesting second order patterns, such as along-strike fluctuations in the Lesser Himalayas and a significant decrease in erodibility coincident with the location of the MCT zone. This latter result possibly highlights the effect of intense schistosity and fracturation on large scale erosion efficiency [Molnar et al., 2007]. Then to assess the influence of erodibility on

  20. Deriving supraglacial debris thickness using satellite data on the Lirung Glacier in the Nepalese Himalayas

    Science.gov (United States)

    Petersen, Lene; Schauwecker, Simone; Brock, Ben; Immerzeel, Walter; Pellicciotti, Francesca

    2013-04-01

    Glaciers with debris-covered ablation zones are widely present in mountain ranges such as the Alps, the Himalayas and the Andes. An expansion of rock debris-covered areas has been documented in recent decades. It is therefore increasingly important to take the effect of debris cover into account in glacio-hydrological modelling. Debris thickness is a key control on a glacier's energy balance and it governs the melt rate beneath debris, hence the estimation of debris extent and thickness is crucial to predict melt. Data on debris thickness are scarce on most glaciers and thus simplified assumptions are commonly used. In this study we test a new, recently developed physically based method to produce debris thickness maps from satellite imagery. The model is based on a solution of the energy balance equation at the debris surface to reconstruct debris thickness as a residual in each satellite pixel. This approach requires ASTER thermal images and reanalysis meteorological data and has the potential to map distribution of debris thickness without the need for detailed field data. In a previous study we tested the model for glaciers with different characteristics and in different climatic regions of the world. The validation of debris thickness, however, is problematic due to data scarcity, the inhomogeneous debris distribution and the resolution of the ASTER product (90 m). The standard application of the model seems to work for glaciers for which debris characteristics such as the effective conductivity are known and reanalysis data are representative. In this study we additionally test the approach with a recently collected data set over the Lirung glacier in the Nepalese Himalayas, where initial application of the remote sensing method using reanalysis data led to a significant underestimation of debris thickness. Extensive field data were collected from May to October 2012 consisting of data from an AWS, spatially distributed air and surface temperature, effective

  1. Selected flavonoids potentiate the toxicity of cisplatin in human lung adenocarcinoma cells: A role for glutathione depletion

    OpenAIRE

    Kachadourian, Remy; LEITNER, VHEATHER M.; Day, Brian J.

    2007-01-01

    Adjuvant therapies that enhance the anti-tumor effects of cisplatin are actively being pursued. Growing evidence supports the involvement of mitochondrial dysfunction in the anti-cancer effect of cis-diammineplatinum(II) dichloride (cisplatin, CDDP). We examined the potential of using selective flavonoids that are effective in depleting tumor cells of glu-tathione (GSH) to potentiate cisplatin-mediated cytotoxicity in human lung adenocarcinoma (A549) cells. We found that cisplatin (40 μM, 48-...

  2. Canopy Temperature Depression as a Potential Selection Criterion for Drought Resistance in Wheat

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    (R2=0.46-0.58) conditions. These results clearly indicated grain yield and water stress can be predicted by taking CTD values in field, which can be used by breeding programs as a potential selection criterion for grain yield and drought resistance in wheat, but a second study year is needed to confirm further.

  3. Potential sources of analytical bias and error in selected trace element data-quality analyses

    Science.gov (United States)

    Paul, Angela P.; Garbarino, John R.; Olsen, Lisa D.; Rosen, Michael R.; Mebane, Christopher A.; Struzeski, Tedmund M.

    2016-09-28

    Potential sources of analytical bias and error associated with laboratory analyses for selected trace elements where concentrations were greater in filtered samples than in paired unfiltered samples were evaluated by U.S. Geological Survey (USGS) Water Quality Specialists in collaboration with the USGS National Water Quality Laboratory (NWQL) and the Branch of Quality Systems (BQS).Causes for trace-element concentrations in filtered samples to exceed those in associated unfiltered samples have been attributed to variability in analytical measurements, analytical bias, sample contamination either in the field or laboratory, and (or) sample-matrix chemistry. These issues have not only been attributed to data generated by the USGS NWQL but have been observed in data generated by other laboratories. This study continues the evaluation of potential analytical bias and error resulting from matrix chemistry and instrument variability by evaluating the performance of seven selected trace elements in paired filtered and unfiltered surface-water and groundwater samples collected from 23 sampling sites of varying chemistries from six States, matrix spike recoveries, and standard reference materials.Filtered and unfiltered samples have been routinely analyzed on separate inductively coupled plasma-mass spectrometry instruments. Unfiltered samples are treated with hydrochloric acid (HCl) during an in-bottle digestion procedure; filtered samples are not routinely treated with HCl as part of the laboratory analytical procedure. To evaluate the influence of HCl on different sample matrices, an aliquot of the filtered samples was treated with HCl. The addition of HCl did little to differentiate the analytical results between filtered samples treated with HCl from those samples left untreated; however, there was a small, but noticeable, decrease in the number of instances where a particular trace-element concentration was greater in a filtered sample than in the associated

  4. Refrigeration Playbook: Natural Refrigerants; Selecting and Designing Energy-Efficient Commercial Refrigeration Systems That Use Low Global Warming Potential Refrigerants

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, Caleb [CTA Architects Engineers, Boise, ID (United States); Reis, Chuck [CTA Architects Engineers, Boise, ID (United States); Nelson, Eric [CTA Architects Engineers, Boise, ID (United States); Armer, James [CTA Architects Engineers, Boise, ID (United States); Arthur, Rob [CTA Architects Engineers, Boise, ID (United States); Heath, Richard [CTA Architects Engineers, Boise, ID (United States); Rono, James [CTA Architects Engineers, Boise, ID (United States); Hirsch, Adam [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Doebber, Ian [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2015-03-01

    This report provides guidance for selecting and designing energy efficient commercial refrigeration systems using low global warming potential refrigerants. Refrigeration systems are generally the largest energy end use in a supermarket type building, often accounting for more than half of a building's energy consumption.

  5. Evolution and outburst risk analysis of moraine-dammed lakes in the central Chinese Himalaya

    Indian Academy of Sciences (India)

    Wang Shijin; Jiao Shitai

    2015-04-01

    The recent evolution and outburst risk of two typical moraine-dammed lakes, Galong and Gangxi, central Chinese Himalaya, are analyzed using topographic maps from 1974 and Landsat satellite imagery acquired in 1988, 2000 and 2014. The datasets show the areas of Galong and Gangxi lakes increasing at rates of 0.45 and 0.34 km2/year during the period 1974–2014, an expansion of 501% and 107%, respectively, in the past 41 years, while the areas of the parent glaciers, Reqiang and Jipucong decreased by 44.22% and 37.76%, respectively. The accelerating retreat of the glaciers not only reflects their generally negative mass balance but is consistent with the rapid expansion of the moraine-dammed lakes. When acted upon by external forces such as earthquakes, heavy rainfall, rapid melting of glaciers and dead ice, and snow/ice/rock avalanches, these lakes can become extremely dangerous, easily forming outburst mudslides, which can potentially spread to the Poiqu river basin and develop into cross-border (China and Nepal) GLOF disasters. Therefore, there is an urgent need to strengthen integrated risk management of glacial lake outburst disasters with multiple objectives and modes.

  6. Natural Resource Conditions and Economic Development in the Uttaranchal Himalaya, India

    Institute of Scientific and Technical Information of China (English)

    Vishwambhar Prasad Sati

    2005-01-01

    Uttaranchal is bestowed with numerous rivers, huge forest resources ranging from tropical to temperate, tourists' places, pilgrimages and feasible climatic conditions for growing fruits, vegetables,food grains, livestock rearing, tea garden practices, etc.The economic development, on the other hand, could not take place partly due to lack of modern technology with innovation in agricultural system and also unwillingness of the people towards using it.Furthermore, due to its harsh climatic conditions,rigorous terrain and distinct identity, as a part of Uttar Pradesh state, the development could not take place and today the state is believed to be one of the poorer states. Infrastructurally, this region is lagged behind due to its inaccessibility. The ideal geographical and agrarian conditions might be used evenly for the developmental processes. Ecologically,the whole region is fragile. The diverse socio-economic activities, harsh traditional beliefs and hard working potentials further change the entire scenario of the state. Only the need of the hours is to frame and implementation of the rational policies and planning for sustainable development of the state.What had appeared during the past, pertaining to the economic development, needs radical changes in policies, planning and beliefs. This paper aims to evaluate the present conditions of resources as a form of natural vegetation, agricultural crops, horticultural farming, herbs, tea garden practices, livestock rearing,hydropower projects and economic development of the Uttaranchal Himalaya.

  7. Mountain Commons: Changing Space and Status at Community Levels in the Himalayas

    Institute of Scientific and Technical Information of China (English)

    Narpat S. JODHA

    2007-01-01

    This paper deals with the imperatives of nature-society interaction in the Himalayas as seen through CPR (Common Property Resources). It specifically looks at the process and factors that characterize the dynamics of the above interactions,with particular reference to the changing status and governance of CPRs at community levels. The paper puts together the synthesis of observations and inferences of different studies by ICIMOD and others in mountain regions, particularly in different parts of Nepal, India, Bhutan, Bangladesh, China and Pakistan. Rural CPRs (providing sustenance supplies and services)as an important component of a community's natural resource base, manifest the institutional arrangements evolved by the communities to facilitate their adaptations to nature.The above process can be more clearly illustrated with reference to specific characteristics of mountain areas,called mountain specificities.However, over time, the situation of CPRs in terms of their extent and status, governance and management as well as contributions to community sustenance, has changed. The paper attempts to indicate potential lead lines for searching options for rehabilitation of CPRs, based on a closer understanding of the factors contributing to their decline.

  8. Recruitment of hornbill-dispersed trees in hunted and logged forests of the Indian Eastern Himalaya.

    Science.gov (United States)

    Sethi, Pia; Howe, Henry F

    2009-06-01

    Hunting of hornbills by tribal communities is widespread in logged foothill forests of the Indian Eastern Himalaya. We investigated whether the decline of hornbills has affected the dispersal and recruitment of 3 large-seeded tree species. We hypothesized that 2 low-fecundity tree species, Chisocheton paniculatus and Dysoxylum binectariferum (Meliaceae) bearing arillate fruits, are more dispersal limited than a prolifically fruiting drupaceous tree Polyalthia simiarum (Annonaceae), which has potential dispersers other than hornbills. We estimated the abundance of large avian frugivores during the fruiting season along transects in 2 protected and 2 disturbed forests. We compared recruitment of the tree species near (Aceros undulatus), and Oriental Pied Hornbills (Anthracoceros albirostris) were significantly lower in disturbed forests, but sites did not differ in abundances of the Mountain Imperial Pigeon (Ducula badia). Overall, tree species showed more severely depressed recruitment of seedlings (77% fewer) and juveniles (69% fewer) in disturbed than in protected forests. In disturbed forests, 93% fewer seedlings of C. paniculatus were beyond parental crowns, and a high number of all seedlings (42%) accumulated directly under reproductive adults. In contrast, D. binectariferum and P. simiarum were recruitment rather than dispersal limited, with fewer dispersed seedlings surviving in disturbed than in protected forests. Results are consistent with the idea that disturbance disrupts mutualisms between hornbills and some large-seeded food plants, with the caveat that role redundancy within even small and specialized disperser assemblages renders other tree species less vulnerable to loss of regular dispersal agents.

  9. Evolution and outburst risk analysis of moraine-dammed lakes in the central Chinese Himalaya

    Science.gov (United States)

    Shijin, Wang; Shitai, Jiao

    2015-04-01

    The recent evolution and outburst risk of two typical moraine-dammed lakes, Galong and Gangxi, central Chinese Himalaya, are analyzed using topographic maps from 1974 and Landsat satellite imagery acquired in 1988, 2000 and 2014. The datasets show the areas of Galong and Gangxi lakes increasing at rates of 0.45 and 0.34 km2/year during the period 1974-2014, an expansion of 501% and 107%, respectively, in the past 41 years, while the areas of the parent glaciers, Reqiang and Jipucong decreased by 44.22% and 37.76%, respectively. The accelerating retreat of the glaciers not only reflects their generally negative mass balance but is consistent with the rapid expansion of the moraine-dammed lakes. When acted upon by external forces such as earthquakes, heavy rainfall, rapid melting of glaciers and dead ice, and snow/ice/rock avalanches, these lakes can become extremely dangerous, easily forming outburst mudslides, which can potentially spread to the Poiqu river basin and develop into cross-border (China and Nepal) GLOF disasters. Therefore, there is an urgent need to strengthen integrated risk management of glacial lake outburst disasters with multiple objectives and modes.

  10. A new remote hazard and risk assessment framework for glacial lakes in the Nepal Himalaya

    Science.gov (United States)

    Rounce, David R.; McKinney, Daene C.; Lala, Jonathan M.; Byers, Alton C.; Watson, C. Scott

    2016-08-01

    Glacial lake outburst floods (GLOFs) pose a significant threat to downstream communities and infrastructure due to their potential to rapidly unleash stored lake water. The most common triggers of these GLOFs are mass movement entering the lake and/or the self-destruction of the terminal moraine due to hydrostatic pressures or a buried ice core. This study initially uses previous qualitative and quantitative assessments to understand the hazards associated with eight glacial lakes in the Nepal Himalaya that are widely considered to be highly dangerous. The previous assessments yield conflicting classifications with respect to each glacial lake, which spurred the development of a new holistic, reproducible, and objective approach based solely on remotely sensed data. This remote hazard assessment analyzes mass movement entering the lake, the stability of the moraine, and lake growth in conjunction with a geometric GLOF to determine the downstream impacts such that the present and future risk associated with each glacial lake may be quantified. The new approach is developed within a hazard, risk, and management action framework with the aim that this remote assessment may guide future field campaigns, modeling efforts, and ultimately risk-mitigation strategies. The remote assessment was found to provide valuable information regarding the hazards faced by each glacial lake and results were discussed within the context of the current state of knowledge to help guide future efforts.

  11. Historical telecommunication in the Hindukush-Karakoram-Himalayas: An ancient early warning system for glacier lake outbursts

    Science.gov (United States)

    Iturrizaga, Lasafam

    2016-04-01

    operated in the entire Hindukush-Karakoram Region including Ladakh. The locations of selected signal fire signal chains have been reconstructed for the Valleys of Shimshal, Karambar and Rupal. Natural hazard management is increasingly dominated by external technological and cost-intensive approaches in the Himalayas. Local traditional knowledge and practical expertise may be given up without an alternative plan for hazard management. Thus, the intervention from external side in traditional mountain societies and the implementation of distinct security expectations has to be well considered at the long-term.

  12. Spatial prediction of landslide susceptibility in parts of Garhwal Himalaya, India, using the weight of evidence modelling.

    Science.gov (United States)

    Guri, Pardeep Kumar; Ray, P K Champati; Patel, Ramesh Chandra

    2015-06-01

    can be carried out in vast stretches of Himalaya in short time in order to assess the impact of development as well as climate change/variability. The resultant map can play a critical role in selecting areas for remedial measures for slope stabilisation as well planning for future development of the region.

  13. Glacial Lake Outburst Flood Risk in the Poiqu/Bhote Koshi/Sun Koshi River Basin in the Central Himalayas

    Directory of Open Access Journals (Sweden)

    Narendra Raj Khanal

    2015-11-01

    Full Text Available The Himalayas have experienced several glacial lake outburst floods (GLOFs, and the risk of GLOFs is now increasing in the context of global warming. Poiqu watershed in the Tibet Autonomous Region, China, also known as the Bhote Koshi and Sun Koshi downstream in Nepal, has been identified as highly prone to GLOFs. This study explored the distribution of and changes in glacial lakes, past GLOFs and the resulting losses, risk from potential future GLOFs, and risk reduction initiatives within the watershed. A relationship was established between lake area and volume of lake water based on data from 33 lakes surveyed within the Hindu Kush Himalayan region, and the maximum possible discharge was estimated using this and other previously developed empirical equations. We recommend different strategies to reduce GLOF risk and highlight the need for a glacial lake monitoring and early-warning system. We also recommend strong regional cooperation, especially on issues related to transboundary rivers.

  14. Seismicity of the Earth 1900–2010 Himalaya and vicinity

    Science.gov (United States)

    Turner, Bethan; Jenkins, Jennifer; Turner, Rebecca; Parker, Amy; Sinclair, Alison; Davies, Sian; Hayes, Gavin P.; Villaseñor, Antonio; Dart, Rirchard L.; Tarr, Arthur C.; Furlong, Kevin P.; Benz, Harley M.

    2013-01-01

    Seismicity in the Himalaya region predominantly results from the collision of the India and Eurasia continental plates, which are converging at a relative rate of 40–50 mm/yr. Northward underthrusting of India beneath Eurasia generates numerous earthquakes and consequently makes this area one of the most seismically hazardous regions on Earth. The surface expression of the plate boundary is marked by the foothills of the north-south trending Sulaiman Range in the west, the Indo-Burmese Arc in the east, and the east-west trending Himalaya Front in the north of India. Along the western margin of the India plate, relative motions between India and Eurasia are accommodated by strike-slip, reverse, and oblique-slip faulting resulting in the complex Sulaiman Range fold and thrust belt, and the major translational Chaman Fault in Afghanistan. Beneath the Pamir‒Hindu Kush Mountains of northern Afghanistan, earthquakes occur to depths as great as 200 km as a result of remnant lithospheric subduction. Further north again, the Tian Shan is a seismically active intra-continental mountain belt defined by a series of east-west trending thrust faults thought to be related to the broad footprint of the India-Eurasia collision. Tectonics in northern India are dominated by motion along the Main Frontal Thrust and associated thrust faults of the India-Eurasia plate boundary, which have resulted in a series of large and devastating earthquakes in (and prior to) the 20th century. The Tibetan Plateau to the north of the main plate boundary is a broad region of uplift associated with the India-Eurasia collision, and is cut by a series of generally east-west trending strike-slip faults. These include the Kunlun, Haiyuan, and the Altyn Tagh faults, all of which are left-lateral structures, and the Kara-Koram right-lateral fault. Throughout the plateau, thrust faults accommodate the north-south compressional component of crustal shortening associated with the ongoing collision of India

  15. Glacial lakes amplify glacier recession in the central Himalaya

    Science.gov (United States)

    King, Owen; Quincey, Duncan; Carrivick, Jonathan; Rowan, Ann

    2016-04-01

    The high altitude and high latitude regions of the world are amongst those which react most intensely to climatic change. Across the Himalaya glacier mass balance is predominantly negative. The spatial and temporal complexity associated with this ice loss across different glacier clusters is poorly documented however, and our understanding of the processes driving change is limited. Here, we look at the spatial variability of glacier hypsometry and glacial mass loss from three catchments in the central Himalaya; the Dudh Koshi basin, Tama Koshi basin and an adjoining section of the Tibetan Plateau. ASTER and SETSM digital elevation models (2014/15), corrected for elevation dependant biases, co-registration errors and along or cross track tilts, are differenced from Shuttle Radar Topographic Mission (SRTM) data (2000) to yield surface lowering estimates. Landsat data and a hypsometric index (HI), a classification scheme used to group glaciers of similar hypsometry, are used to examine the distribution of glacier area with altitude in each catchment. Surface lowering rates of >3 m/yr can be detected on some glaciers, generally around the clean-ice/debris-cover boundary, where dark but thin surface deposits are likely to enhance ablation. More generally, surface lowering rates of around 1 m/yr are more pervasive, except around the terminus areas of most glaciers, emphasising the influence of a thick debris cover on ice melt. Surface lowering is only concentrated at glacier termini where glacial lakes have developed, where surface lowering rates are commonly greater than 2.5 m/yr. The three catchments show contrasting hypsometric distributions, which is likely to impact their future response to climatic changes. Glaciers of the Dudh Koshi basin store large volumes of ice at low elevation (HI > 1.5) in long, debris covered tongues, although their altitudinal range is greatest given the height of mountain peaks in the catchment. In contrast, glaciers of the Tama Koshi

  16. Carbon allocation, sequestration and carbon dioxide mitigation under plantation forests of north western Himalaya, India

    Directory of Open Access Journals (Sweden)

    Bandana Devi

    2013-07-01

    Full Text Available The organic carbon and soils of the world comprise bulk of the terrestrial carbon and serve as amajorsink and source of atmospheric carbon. Increasing atmospheric concentrations of green house gases may be mitigated by increasing carbon sequestration in vegetation and soil. The study attempted to estimate biomass production and carbon sequestration potential of different plantation ecosystems in north western Himalaya, India. Biomass, carbon density of biomass, soil, detritus, carbon sequestration and CO2 mitigation potential were studied underdifferent plantation forest ecosystems comprising of eight different tree species viz. Quercus leucotrichophora, Pinus roxburghii, Acacia catechu, Acacia mollissima, Albizia procera, Alnus nitida, Eucalyptus tereticornis and Ulmus villosa. Above (185.57 ą 48.99 tha-1 and below ground (42.47 ą 10.38 tha-1 biomass was maximum in Ulmus villosa. The vegetation carbon density was maxium in Albizia procera (118.37 ą 1.49 tha-1 and minimum (36.50 ą 9.87 tha-1 in Acacia catechu. Soil carbon density was maximum (219.86ą 10.34 tha-1 in Alnus nitida, and minimum (170.83ą 20.60 tha-1in Pinus roxburghii. Detritus was higher in Pinus roxburghii (6.79 ą 2.0 tha-1. Carbon sequestration (7.91ą 3.4 tha-1 and CO2 mitigation potential (29.09 ą 12.78 tha-1 was maximum in Ulmus villosa. Pearson correlation matrix revealed significant positive relationship of ecosystem carbon with plantation biomass, soil carbon and CO2 mitigation potential. With the emerging threat of climate change, such assessment of forest and soil carbon inventory would allow to devise best land management and policy decisions forsustainable management of fragile hilly ecosystem. 

  17. Depositional environment and provenance of Middle Siwalik sediments in Tista valley, Darjiling District, Eastern Himalaya, India

    Indian Academy of Sciences (India)

    Abhik Kundu; Abdul Matin; Malay Mukul

    2012-02-01

    The frontal part of the active, wedge-shaped Indo-Eurasian collision boundary is defined by the Himalayan fold-and-thrust belt whose foreland basin accumulated sediments that eventually became part of the thrust belt and is presently exposed as the sedimentary rocks of the Siwalik Group. The rocks of the Siwalik Group have been extensively studied in the western and Nepal Himalaya and have been divided into the Lower, Middle and Upper Subgroups. In the Darjiling–Sikkim Himalaya, the Upper Siwalik sequence is not exposed and the Middle Siwalik Subgroup exposed in the Tista river valley of Darjiling Himalaya preserves a ∼325 m thick sequence of sandstone, conglomerate and shale. The Middle Siwalik section has been repeated by a number of north dipping thrusts. The sedimentary facies and facies associations within the lithostratigraphic column of the Middle Siwalik rocks show temporal repetition of sedimentary facies associations suggesting oscillation between proximal-, mid- and distal fan setups within a palaeo-alluvial fan depositional environment similar to the depositional setup of the Siwalik sediments in other parts of the Himalaya. These oscillations are probably due to a combination of foreland-ward movement of Himalayan thrusts, climatic variations and mountain-ward shift of fanapex due to erosion. The Middle Siwalik sediments were derived from Higher- and Lesser Himalayan rocks. Mineral characteristics and modal analysis suggest that sedimentation occurred in humid climatic conditions similar to the moist humid climate of the present day Eastern Himalaya.

  18. Precipitation and snow cover in the Himalaya: from reanalysis to regional climate simulations

    Directory of Open Access Journals (Sweden)

    M. Ménégoz

    2013-10-01

    Full Text Available We applied a Regional Climate Model (RCM to simulate precipitation and snow cover over the Himalaya, between March 2000 and December 2002. Due to its higher resolution, our model simulates a more realistic spatial variability of wind and precipitation than those of the reanalysis of the European Centre of Medium range Weather Forecast (ECMWF used as lateral boundaries. In this region, we found very large discrepancies between the estimations of precipitation provided by reanalysis, rain gauges networks, satellite observations, and our RCM simulation. Our model clearly underestimates precipitation at the foothills of the Himalaya and in its eastern part. However, our simulation provides a first estimation of liquid and solid precipitation in high altitude areas, where satellite and rain gauge networks are not very reliable. During the two years of simulation, our model resembles the snow cover extent and duration quite accurately in these areas. Both snow accumulation and snow cover duration differ widely along the Himalaya: snowfall can occur during the whole year in western Himalaya, due to both summer monsoon and mid-latitude low pressure systems bringing moisture into this region. In Central Himalaya and on the Tibetan Plateau, a much more marked dry season occurs from October to March. Snow cover does not have a pronounced seasonal cycle in these regions, since it depends both on the quite variable duration of the monsoon and on the rare but possible occurrence of snowfall during the extra-monsoon period.

  19. [A potential of selective androgen receptor modulator(SARM)for the therapy of osteoporosis].

    Science.gov (United States)

    Yanase, Toshihiko

    2016-07-01

    In recent years, the drugs, which show anabolic, effect on bone and muscle without stimulating prostate has been developed. They show tissue-specific selective androgen actions and called selective androgen receptor modulators(SARMs). The development of drug targeting bone and muscle in male is very promising as a treatment tool for osteoporosis and sarcopenia in the near future. The clinical study is under going especially in the field of cachexia associated with cancer, but unfortunately there is no drug in the current market at present. The current situation of the development of SARMs will be reviewed.

  20. Radiosensitizing potential of the selective cyclooygenase-2 (COX-2) inhibitor meloxicam on human glioma cells

    NARCIS (Netherlands)

    Bijnsdorp, Irene; Berg, van den Jaap; Kuipers, Gitta; Wedekind, Laurine; Slotman, Ben; Rijn, van Johannes; Lafleur, M.; Sminia, Peter

    2007-01-01

    The COX-2 protein is frequently overexpressed in human malignant gliomas. This expression has been associated with their aggressive growth characteristics and poor prognosis for patients. Targeting the COX-2 pathway might improve glioma therapy. In this study, the effects of the selective COX-2 in

  1. The influence of caffeine on spatial-selective attention : an event-related potential study

    NARCIS (Netherlands)

    de Ruiter, MB; Snel, J; Lorist, MM; Ruijter, J

    2000-01-01

    Objectives: Following the indications of previous studies that caffeine might have a specific effect on the processing of spatial information compared with other types of information, the present study investigated the influence of caffeine on an often used spatial-selective attention task. Methods:

  2. Survey on basic knowledge about exposure and potential environmental and health risks for selected nanomaterials

    DEFF Research Database (Denmark)

    Mikkelsen, Sonja Hagen; Hansen, Erik; Christensen, Trine Boe

    Based on a literature review this report provides a general description as well as an environmental and health profile of 7 nanomaterials. The examined nanomaterials are selected because of expected high use or specific environmental and health properties. Fullerenes, iron, silver, nanoclay...... other nanomaterials were identified, there are areas where there may be reason for attention and thus need for more knowledge....

  3. Chalcone-based Selective Inhibitors of a C4 Plant Key Enzyme as Novel Potential Herbicides

    Science.gov (United States)

    Nguyen, G. T. T.; Erlenkamp, G.; Jäck, O.; Küberl, A.; Bott, M.; Fiorani, F.; Gohlke, H.; Groth, G.

    2016-06-01

    Weeds are a challenge for global food production due to their rapidly evolving resistance against herbicides. We have identified chalcones as selective inhibitors of phosphoenolpyruvate carboxylase (PEPC), a key enzyme for carbon fixation and biomass increase in the C4 photosynthetic pathway of many of the world’s most damaging weeds. In contrast, many of the most important crop plants use C3 photosynthesis. Here, we show that 2‧,3‧,4‧,3,4-Pentahydroxychalcone (IC50 = 600 nM) and 2‧,3‧,4‧-Trihydroxychalcone (IC50 = 4.2 μM) are potent inhibitors of C4 PEPC but do not affect C3 PEPC at a same concentration range (selectivity factor: 15–45). Binding and modeling studies indicate that the active compounds bind at the same site as malate/aspartate, the natural feedback inhibitors of the C4 pathway. At the whole plant level, both substances showed pronounced growth-inhibitory effects on the C4 weed Amaranthus retroflexus, while there were no measurable effects on oilseed rape, a C3 plant. Growth of selected soil bacteria was not affected by these substances. Our chalcone compounds are the most potent and selective C4 PEPC inhibitors known to date. They offer a novel approach to combat C4 weeds based on a hitherto unexplored mode of allosteric inhibition of a C4 plant key enzyme.

  4. Therapeutic applications of selective and non-selective inhibitors of monoamine oxidase A and B that do not cause significant tyramine potentiation.

    Science.gov (United States)

    Youdim, Moussa B H; Weinstock, Marta

    2004-01-01

    The major side effect with the use of first generation of non selective monoamine oxidase (MAO) inhibitors as neuropsychiatric drugs was what became known as the "cheese reaction". Namely, potentiation of sympathomimetic activity of ingested tyramine present in cheese and other food stuff, resulting from its ability to release noradrenaline, when prevented from metabolism by MAO. The identification of two forms of MAO, termed types A and B and their selective irreversible inhibitors resolved some of this problems. However irreversible MAO-A inhibitors continue to induce a cheese reaction, whereas MAO-B inhibitors at their selective dosage did not and led to introduction of L-deprenyl (selegiline) as an anti-Parkinson drug, since dopamine is equally well metabolized by both enzyme forms. The cheese reaction is a consequence of inhibition of MAO-A, the enzyme responsible for metabolism of noradrenaline and serotonin, located in peripheral adrenergic neurons. The consequence of these findings were the development of reversible MAO-A inhibitors (RIMA), moclobemide and brofaromin, as antidepressants and possible anti-Parkinson activity, with limited tyramine potentiation, since the amine can displace the inhibitor from its binding site on the enzyme. It has always been deemed a greater pharmacological advantage to inhibit both forms of the enzymes to get the full functional activities of the amine neurotransmitters, and without inducing a "cheese reaction". This was not possible until recently, with the development of the novel cholinesterase-brain selective MAO-AB inhibitor, TV3326 (N-propargyl-(3R)-aminoidnan-5-yl-ethyl methylcarbamate hemitartiate), a carbamate derivative of the irreversible MAO-B inhibitor anti-Parkinson drug, rasagiline. This drug is a brain selective MAO-A and B inhibitor, with little inhibition of liver and small intestine enzymes. Pharmacologically it has limited tyramine potentiation, very similar to moclobemide and being a MAO-AB inhibitor it

  5. Ethnobotanical uses of biofencing plants in Himachal Pradesh, Northwest Himalaya.

    Science.gov (United States)

    Sharma, Pankaj; Devi, Usha

    2013-12-15

    The aim of this study is to document the traditional knowledge on the utilization of Biofencing plants of Himachal Pradesh, Northwest Himalaya. The study was imperative because of dearth in the data pertaining to Biofencing plants in the study areas. The whole study area was stratified into three zones and a widespread field survey and random sampling method was adopted to assess the live fencing diversity of the region. The region occupies total 61 species. 10 (trees), 45 (shrubs), 4 (herbs) and 2 were climbers. These belong to the 25 families. Rosaceae, Fabaceae, Berberidaceae, Elaeagnaceae and Euphorbiaceae are dominant families. Among genera, Berberis and Rosa are dominant. Of the total, 55 species are medicinally important and among these 20% are used for stomach disorders; 17% (skin complaints), 14% (asthma), 11% (fever and joint pains), 3% (aphrodisiac and snake bite), 1% (anticancerous and nerve disorders). Ethnobotanical assessment showed that 33 of the recorded species are used as fuel, 20 (edible), 8 (fodder) and 4 (fiber and ornamental). This traditional knowledge of Biofencing plants contributes to the conservation of biodiversity and provides resource of economic and ecological interest and also decreasing the pressure on forests. So there is need to encourage the practice of using plant species for fencing in this region.

  6. Glaciological and hydrological sensitivities in the Hindu Kush - Himalaya

    Science.gov (United States)

    Shea, Joseph; Immerzeel, Walter

    2016-04-01

    Glacier responses to future climate change will affect hydrology at subbasin-scales. The main goal of this study is to assess glaciological and hydrological sensitivities of sub-basins throughout the Hindu Kush - Himalaya (HKH) region. We use a simple geometrical analysis based on a full glacier inventory and digital elevation model (DEM) to estimate sub-basin equilibrium line altitudes (ELA) from assumptions of steady-state accumulation area ratios (AARs). The ELA response to an increase in temperature is expressed as a function of mean annual precipitation, derived from a range of high-altitude studies. Changes in glacier contributions to streamflow in response to increased temperatures are examined for scenarios of both static and adjusted glacier geometries. On average, glacier contributions to streamflow increase by approximately 50% for a +1K warming based on a static geometry. Large decreases (-60% on average) occur in all basins when glacier geometries are instantaneously adjusted to reflect the new ELA. Finally, we provide estimates of sub-basin glacier response times that suggest a majority of basins will experience declining glacier contributions by the year 2100.

  7. Asynchronous glaciation at Nanga Parbat, northwestern Himalaya Mountains, Pakistan

    Science.gov (United States)

    Phillips, William M.; Sloan, Valerie F.; Shroder, John F., Jr.; Sharma, Pankaj; Clarke, Michèle L.; Rendell, Helen M.

    2000-05-01

    We present a new glacial chronology demonstrating asynchroneity between advances of Himalayan glaciers and Northern Hemisphere ice-sheet volumes. Glaciers at Nanga Parbat expanded during the early to middle Holocene ca. 9.0 5.5 ka. No major advances at Nanga Parbat during the last global glacial stage of marine oxygen isotope stage 2 (MIS-2) between 24 and 11 ka were identified. Preliminary evidence also indicates advances between ca. 60 and 30 ka. These periods of high ice volume coincide with warm, wet regional climates dominated by a strong southwest Asian summer monsoon. The general lack of deposits dating from MIS-2 suggests that Nanga Parbat was too arid to support expanded ice during this period of low monsoon intensity. Advances during warm, wet periods are possible for the high-altitude summer accumulation glaciers typical of the Himalayas, and explain asynchronous behavior. However, the Holocene advances at Nanga Parbat appear to have been forced by an abrupt drop in temperature ca. 8.4 8.0 ka and an increase in winter precipitation ca. 7 5.5 ka. These results highlight the overall sensitivity of Himalayan glaciation to orbital forcing of monsoon intensity, and on millennial or shorter time scales, to changes in North Atlantic circulation.

  8. The mammalian fauna from the Central Himalaya, Nepal

    Directory of Open Access Journals (Sweden)

    Hem Bahadur Katuwal

    2013-07-01

    Full Text Available Nepal harbors unique mammalian fauna, but it is poorly studied at higher elevation. Mammalian fauna were recorded in Manaslu Conservation Area, Dudhkunda and Dudhkoshi valley of Solukhumbu district and Kanchenjunga Conservation Area of Nepal during March 2011 to April 2013 along the trail and the study plots from 700m to 4400m a.s.l. Semi-structured interviews were made with local people to understand their behavior and habitats. Altogether, 29 mammalian fauna were recorded. Five species were recorded new for the areas. Overall, Carnivore species (nine were encountered more, followed by species of the order Cetartiodactyla (seven. The highest number of mammalian fauna (18 was identified from Manaslu Conservation Area whereas the least (11 from Dudhkunda and Dudhkoshi valley. Human wildlife conflict was frequent with Himalayan Goral (Naemorhedus goral, Barking Deer (Muntiacus vaginalis, Himalayan Tahr (Hemitragus jemlahicus, Rhesus Macaque (Macaca mulatta, Nepal Grey Langur (Semnopithecus schistaceus and Himalayan Black Bear (Ursus thibetanus for crop depredation in these areas. Although mammalian research started a long time ago, scenario of comprehensive research is not satisfactory in the Central Himalaya, Nepal.

  9. Mapping Deforestation and Forest Degradation Patterns in Western Himalaya, Pakistan

    Directory of Open Access Journals (Sweden)

    Faisal Mueen Qamer

    2016-05-01

    Full Text Available The Himalayan mountain forest ecosystem has been degrading since the British ruled the area in the 1850s. Local understanding of the patterns and processes of degradation is desperately required to devise management strategies to halt this degradation and provide long-term sustainability. This work comprises a satellite image based study in combination with national expert validation to generate sub-district level statistics for forest cover over the Western Himalaya, Pakistan, which accounts for approximately 67% of the total forest cover of the country. The time series of forest cover maps (1990, 2000, 2010 reveal extensive deforestation in the area. Indeed, approximately 170,684 ha of forest has been lost, which amounts to 0.38% per year clear cut or severely degraded during the last 20 years. A significant increase in the rate of deforestation is observed in the second half of the study period, where much of the loss occurs at the western borders along with Afghanistan. The current study is the first systematic and comprehensive effort to map changes to forest cover in Northern Pakistan. Deforestation hotspots identified at the sub-district level provide important insight into deforestation patterns, which may facilitate the development of appropriate forest conservation and management strategies in the country.

  10. Radon in groundwater of eastern Doon valley, Outer Himalaya

    Energy Technology Data Exchange (ETDEWEB)

    Choubey, V.M. E-mail: vchoubey1@rediffmail.com; Bartarya, S.K.; Ramola, R.C

    2003-06-01

    The radon content in water may serve as a useful tracer for several geohydrological processes. The hydrodynamic factor, presence of radium in host rocks, as well as the soil porosity and permeability control its concentration in groundwater. In order to understand the factors that control the occurrence of radon in groundwater of Doon valley in Outer Himalaya, a total of 34 groundwater samples were collected from handpumps and tubewells covering three hydrogeological units/areas in the eastern part of Doon valley. Radon variation in tubewells and handpumps varies from 25.4{+-}1.8 to 92.5{+-}3.4 Bq/l with an average of 53.5{+-}2.6 Bq/l. A significant positive correlation between radon concentration and depth of the wells was observed in the Doiwala-Dudhli and Jolleygrant areas suggesting that radon concentration increases with drilling depth in areas consisting of sediments of younger Doon gravels, whereas samples of the Ganga catchment show negative correlation. The high radon levels at shallower depths in the Ganga catchment (consisting of fluvial terraces of Ganga basin) indicate uranium-rich sediments at shallower depth.

  11. Dietzia kunjamensis sp. nov., isolated from the Indian Himalayas.

    Science.gov (United States)

    Mayilraj, S; Suresh, K; Kroppenstedt, R M; Saini, H S

    2006-07-01

    A coral-red-pigmented actinobacterium, strain K30-10(T), was isolated from a soil sample from a cold desert of the Indian Himalayas. Chemical and phenotypic properties of strain K30-10(T) were consistent with its classification in the genus Dietzia. It showed 97.9 % 16S rRNA gene sequence similarity to Dietzia maris MTCC 7011(T); similarities to the type strains of three other species of the genus, Dietzia natronolimnaea, Dietzia psychralcaliphila and Dietzia cinnamea, were 94.4-96.0 %. The DNA-DNA relatedness between K30-10(T) and the closely related strain D. maris MTCC 7011(T) was 59.2 %. The DNA G+C content of strain K30-10(T) was 67.0 mol%. Based on physiological and biochemical tests and genotypic differences between strain K30-10(T) and its closest phylogenetic relatives, it is proposed that this strain represents a novel species, Dietzia kunjamensis sp. nov.; the type strain is K30-10(T) (=MTCC 7007(T)=DSM 44907(T)=JCM 13325(T)).

  12. Ornithinimicrobium kibberense sp. nov., isolated from the Indian Himalayas.

    Science.gov (United States)

    Mayilraj, S; Saha, P; Suresh, K; Saini, H S

    2006-07-01

    A buff-yellow-pigmented bacterium, strain K22-20(T), which was isolated from a cold desert of the Indian Himalayas, was subjected to a polyphasic taxonomic study. Phenotypic and chemical properties of strain K22-20(T) were consistent with its classification in the genus Ornithinimicrobium. The major fatty acids of the strain were iso-C(17 : 1)omega9c (cis-15-methyl 7-hexadecenoic acid), iso-C(15 : 0) (13-methyl tetradecanoic acid), iso-C(16 : 0) (14-methyl pentadecanoic acid) and iso-C(17 : 0) (15-methyl hexadecanoic acid). The G+C content of the genomic DNA was 71 mol%. According to 16S rRNA gene sequence analysis, strain K22-20(T) was closely related to Ornithinimicrobium humiphilum HKI 0124(T) (97.7 %). However, genomic relatedness between strain K22-20(T) and O. humiphilum MTCC 6406(T), as revealed by DNA-DNA hybridization, was 64.5 %. Based on the polyphasic data, strain K22-20(T) (=MTCC 6545(T)=DSM 17687(T)=JCM 12763(T)) represents a novel species of the genus Ornithinimicrobium, for which the name Ornithinimicrobium kibberense sp. nov. is proposed.

  13. Survey of radon and thoron in homes of Indian Himalaya.

    Science.gov (United States)

    Ramola, Rakesh Chand

    2011-07-01

    Measurements of radon, thoron and their progeny were carried out in some houses from Garhwal and Kumaun Himalayas of India using a LR-115 plastic track detector. The measurements were made in various residential houses of the area at a height of 2.5 m above the ground level using a twin chamber radon dosemeter, which can record the values of radon, thoron and their progeny separately. The concentrations of radon and thoron in these homes were found to vary from 11 to 191 and 1 to 156 Bq m(-3), respectively. The equilibrium factor between radon and progeny varies from 0.02 to 0.90, with an average of 0.26 for the region. The resulting dose rate due to radon, thoron and their decay products was found to vary from 0.02 to 0.84 μSv h(-1) with an arithmetic mean of 0.27 μSv h(-1). A detailed analysis of the distribution of radon, thoron and their decay products inside a house is also reported. The observed dose rates due to radon, thoron and progeny were found somewhat higher but well below the international recommendations.

  14. Seismic slip deficit in the Kashmir Himalaya from GPS observations

    Science.gov (United States)

    Schiffman, Celia; Bali, Bikram Singh; Szeliga, Walter; Bilham, Roger

    2013-11-01

    measurements in Kashmir Himalaya reveal range-normal convergence of 11 ± 1 mm/yr with dextral shear of 5 ± 1 mm/yr. The transition from a fully locked 170 km wide décollement to the unrestrained descending Indian plate occurs at ~25 km depth over an ~23 km wide transition zone. The convergence rate is consistent with the lower bounds of geological estimates for the Main Frontal Thrust, Riasi, and Balapora fault systems, on which no surface slip has been reported in the past millennium. Of the 14 damaging Kashmir earthquakes since 1123, none may have exceeded Mw = 7.6. Therefore, either a seismic moment deficit equivalent to a Mw ≈ 8.7 earthquake exists or the historical earthquake magnitudes have been underestimated. Alternatively, these earthquakes have occurred on reverse faults in the Kashmir Valley, and the décollement has been recently inactive. Although this can reconcile the inferred and theoretical moment release, it is quantitatively inconsistent with observed fault slip in Kashmir.

  15. Vegetational Diversity Analysis across Different Habitats in Garhwal Himalaya

    Directory of Open Access Journals (Sweden)

    Vardan Singh Rawat

    2014-01-01

    Full Text Available Four forest sites varying in vegetation types were studied along an altitudinal range between 2200 and 2500 m. Maximum tree, shrub, and herb species were recorded on stream bank site (22, 25, and 54, resp.. Pteridophytes and bryophytes species richness was maximum on moist site (4 and 5, resp.. The number of climbers was greater in moist and dry habitats (7 species each. Parasitic species were restricted only on dry and stream bank habitats. Restricted tree and shrub species were greater on stream bank site and dry site, respectively. The herb and climber species were greater on moist site. The distribution and species richness pattern in this elevational range largely depend on the altitude and climatic variables. Along the entire range of Garhwal Himalaya, the overlapping among species regimes is broad; therefore, transitional communities having mixture of many species and zones are present. The present study indicates that the opening canopies increase the richness of tree, shrub, herb, and climbers.

  16. Potential influence of selection criteria on the demographic composition of students in an Australian medical school

    Directory of Open Access Journals (Sweden)

    Puddey Ian B

    2011-11-01

    Full Text Available Abstract Background Prior to 1999 students entering our MBBS course were selected on academic performance alone. We have now evaluated the impact on the demographics of subsequent cohorts of our standard entry students (those entering directly from high school of the addition to the selection process of an aptitude test (UMAT, a highly structured interview and a rural incentive program. Methods Students entering from 1985 to 1998, selected on academic performance alone (N = 1402, were compared to those from 1999 to 2011, selected on the basis of a combination of academic performance, interview score, and UMAT score together with the progressive introduction of a rural special entry pathway (N = 1437. Results Males decreased from 57% to 45% of the cohort, students of NE or SE Asian origin decreased from 30% to 13%, students born in Oceania increased from 52% to 69%, students of rural origin from 5% to 21% and those from independent high schools from 56% to 66%. The proportion of students from high schools with relative socio-educational disadvantage remained unchanged at approximately 10%. The changes reflect in part increasing numbers of female and independent high school applicants and the increasing rural quota. However, they were also associated with higher interview scores in females vs males and lower interview scores in those of NE and SE Asian origin compared to those born in Oceania or the UK. Total UMAT scores were unrelated to gender or region of origin. Conclusions The revised selection processes had no impact on student representation from schools with relative socio-educational disadvantage. However, the introduction of special entry quotas for students of rural origin and a structured interview, but not an aptitude test, were associated with a change in gender balance and ethnicity of students in an Australian undergraduate MBBS course.

  17. Assessment of biomethanation potential of selected industrial organic effluents in India

    Energy Technology Data Exchange (ETDEWEB)

    Lata, Kusum; Kansal, Arun; Balakrishnan, Malini; Rajeshwari, K.V.; Kishore, V.V.N. [Tata Energy Research Institute, Darbari Seth Block, Habitat Place, Lodhi Road, 110 003 New Delhi (India)

    2002-05-01

    Anaerobic digestion is gaining wider acceptance in the present scenario over aerobic treatment due to production of biogas, which can be further used for meeting a part of energy demand. On the basis of primary and secondary data, the energy potential by the anaerobic digestion of the effluent from some of the polluting industries has been estimated in this paper. The pulp and paper industry has been found to have the maximum potential among others of the order of 1131 GWh{sub e}/a followed by distillery with a contribution of 830 GWh{sub e}/a to a total potential of 2963 GWh{sub e}/a equivalent electric energy. A total potential of 565 MW plant installation with anaerobic digestion technology has been estimated. The paper also describes the nature of wastewater generated by each sector, status of technologies for that sector in India and policy measures, which should be adopted for their large-scale adoption.

  18. Geological investigations at a high altitude, remote coal mine on the Northwest Pakistan and Afghanistan frontier, Karakoram Himalaya

    Energy Technology Data Exchange (ETDEWEB)

    Donnelly, Laurance J. [Chartered Geologist, Halcrow Group Ltd., Deanway Technology Centre, Wilmslow Road, Handforth, Cheshire, SK9 3FB (United Kingdom)

    2004-12-03

    The Northwest Pakistan and Afghanistan frontier is located one of the most remote, inaccessible, and inhospitable part of the Himalayan orogenic belt. In this region, two of the world's largest and most distinct mountain belts intersect; the Karakoram Himalaya (mainly in Pakistan) and the Hindu Kush (mainly in Afghanistan). Located at high altitude, in a remote part of Northwest Pakistan, close to the border with Afghanistan, tribal villagers began excavating a series of audits into the steep mountain slopes, beneath glaciers, to extract valuable coal and carbonaceous shale resources. These were discovered in 1996, by the villagers, whilst hunting, and may represent some of the highest mine workings in the world. Small-scale mining operations subsequently developed using rudimentary mining methods and the mine became known as the Reshit or Pamir Coal Mine.The coal deposits are sedimentary, highly disturbed and tectonised, having been subjected to multiple phases of orogenic crustal deformation. The coal occurs as discrete lenses, several tens of metres in their lateral dimension, between steeply dipping, overturned and thrusted limestone beds of Jurassic age. The coal provided a vital, alternative source of fuel for the villagers since the local, traditional fuel supply was wood, which had become severely depleted, and imports of kerosene from neighbouring China and Afghanistan were too expensive. The mining operations experienced severe problems. These included several collapses of mine entrances, the failure of the adits to intersect the coal-bearing zones, the potential threat of geological hazards, mining-induced hazards and harsh high-altitude operating conditions, particularly during the winter months. International aid was provided to assist the villagers and a geological investigation was commissioned to investigate the problems at the mine. The geology of Karakoram Himalaya is relatively poorly understood. Until recently the region was restricted to

  19. H+CH4 → H2 + CH3 initial state-selected reaction probabilities on different potential energy surfaces

    Science.gov (United States)

    Ellerbrock, Roman; Manthe, Uwe

    2017-01-01

    Initial state-selected reaction probabilities for the H +CH4 →H2 +CH3 reaction on a recently developed potential energy surface which employs neutral network fitting based on permutational invariant polynomials are reported. The quantum dynamics calculations use the quantum transition state concept and the multi-layer multi-configurational time-dependent Hartree approach and study the reaction process in full-dimensionality for vanishing total angular momentum. A detailed comparison with previous results obtained on other high-level potential energy surfaces is given. The connection between the level of quantum state resolution and the sensitivity of the results on differences in the potential energy surfaces is highlighted. Employing a decomposition of the total reactivity into contributions of the different vibrational states of the activated complex, it is found that differences between the potential energy surfaces are mainly related to the umbrella motion of the methyl group.

  20. Discovery of Selective Small Molecule ROMK Inhibitors as Potential New Mechanism Diuretics

    Science.gov (United States)

    2012-01-01

    The renal outer medullary potassium channel (ROMK or Kir1.1) is a putative drug target for a novel class of diuretics that could be used for the treatment of hypertension and edematous states such as heart failure. An internal high-throughput screening campaign identified 1,4-bis(4-nitrophenethyl)piperazine (5) as a potent ROMK inhibitor. It is worth noting that this compound was identified as a minor impurity in a screening hit that was responsible for all of the initially observed ROMK activity. Structure–activity studies resulted in analogues with improved rat pharmacokinetic properties and selectivity over the hERG channel, providing tool compounds that can be used for in vivo pharmacological assessment. The featured ROMK inhibitors were also selective against other members of the inward rectifier family of potassium channels. PMID:24900480

  1. Widespread climate change in the Himalayas and associated changes in local ecosystems.

    Directory of Open Access Journals (Sweden)

    Uttam Babu Shrestha

    Full Text Available BACKGROUND: Climate change in the Himalayas, a biodiversity hotspot, home of many sacred landscapes, and the source of eight largest rivers of Asia, is likely to impact the well-being of ~20% of humanity. However, despite the extraordinary environmental, cultural, and socio-economic importance of the Himalayas, and despite their rapidly increasing ecological degradation, not much is known about actual changes in the two most critical climatic variables: temperature and rainfall. Nor do we know how changes in these parameters might impact the ecosystems including vegetation phenology. METHODOLOGY/PRINCIPAL FINDINGS: By analyzing temperature and rainfall data, and NDVI (Normalized Difference Vegetation Index values from remotely sensed imagery, we report significant changes in temperature, rainfall, and vegetation phenology across the Himalayas between 1982 and 2006. The average annual mean temperature during the 25 year period has increased by 1.5 °C with an average increase of 0.06 °C yr(-1. The average annual precipitation has increased by 163 mm or 6.52 mmyr(-1. Since changes in temperature and precipitation are immediately manifested as changes in phenology of local ecosystems, we examined phenological changes in all major ecoregions. The average start of the growing season (SOS seems to have advanced by 4.7 days or 0.19 days yr(-1 and the length of growing season (LOS appears to have advanced by 4.7 days or 0.19 days yr(-1, but there has been no change in the end of the growing season (EOS. There is considerable spatial and seasonal variation in changes in climate and phenological parameters. CONCLUSIONS/SIGNIFICANCE: This is the first time that large scale climatic and phenological changes at the landscape level have been documented for the Himalayas. The rate of warming in the Himalayas is greater than the global average, confirming that the Himalayas are among the regions most vulnerable to climate change.

  2. Literature Review: Validity and Potential Usefulness of Psychomotor Ability Tests for Personnel Selection and Classification

    Science.gov (United States)

    1988-04-01

    example, Eysenck has defined a factor as "a hypothetical [emphasis added] causal influence underlying and determining the observed relationships between a...set of variables" ( Eysenck , 1953, p. 108). Ac- cording to Eysenck , factors are useful for providing a unifying structure for viewing the world...employee selection procedures (1978). federal Register, 43, 38290-38315. Eysenck , H. J. (1953). The logical basis of factor analysis. American

  3. The assessment of genetic potential in performance tested gilts by means of selection indexes method

    Directory of Open Access Journals (Sweden)

    Popovac Mladen

    2014-01-01

    Full Text Available The objective of this research paper was to make an assessment of breeding value of performance tested gilts of Swedish Landrace and F1 crossbreds of Swedish Landrace and Great Yorkshire by the method of selection index. The traits on whose basis the breeding value was estimated were: daily liveweight gain, average backfat thickness measured at two sites and carcass meat percentage. These traits were corrected for body mass of 100kg by the method of base indexes and the following average values were determined: corrected daily liveweight gain (KZDP 408.93g/day, corrected average backfat thickness measured at two sites (KSL 9.77mm and corrected carcass meat percentage (KPM 61.08%. Studying the effect of genotype, year and birth season of gilts a statistically significant variation (P>0.05 of these traits provoked by the mentioned factors was not determined while the gilts` sire statistically highly significantly (P<0.001 influenced all studied traits. Heritability coefficients were: h2= 0.255 for KZDP, h2= 0.356 for KSL and h2 = 0.349 for KPM. The four selection index equations were constructed among which as the most optimal was chosen the one which includes all three traits (KZDP, KSL and KPM and whose coefficient of the correlation of selection index and aggregate genotype was rIAG = 0.594. [Projekat Ministarstva nauke Republike Srbije, br. TR31081

  4. Patagonian red wines: selection of Lactobacillus plantarum isolates as potential starter cultures for malolactic fermentation.

    Science.gov (United States)

    Bravo-Ferrada, Bárbara Mercedes; Hollmann, Axel; Delfederico, Lucrecia; Valdés La Hens, Danay; Caballero, Adriana; Semorile, Liliana

    2013-09-01

    The aim of this study was to evaluate fifty-three Lactobacillus plantarum isolates obtained from a Patagonian red wine, molecularly identified and typified using RAPD analysis, in order to select starter cultures for malolactic fermentation (MLF). The results obtained suggest a considerable genetic diversity, taking into account that all L. plantarum isolates were obtained from one cellar and one vintage. Based on the capacity to tolerate a concentration of 14 % ethanol in MRS broth for 2 days, eight isolates were selected for the subsequent analysis. The incidence of various wine stress factors (ethanol, acid pH, lysozyme and sulfur dioxide) on isolates growth was studied. Besides, glucosidase and tannase activities were evaluated, and the presence of genes involved in the synthesis of biogenic amines was examined by PCR. A previously characterized indigenous Oenococcus oeni strain was included with comparative purposes. Differences in technologically relevant characteristics were observed among the eight L. plantarum selected isolates, revealing an isolate-dependent behavior. Detectable glucosidase and tannase activities were found in all isolates. The presence of genes encoding histidine and tyrosine descarboxylases and putrescine carbamoyltransferase was not detected. The ability of L. plantarum isolates to grow and consume L-malic acid in simulated laboratory-scale vinifications revealed that two of them could be considered as possible MLF starter cultures for Patagonian red wines. These isolates will be subjected to further analysis, for a final winery technological characterization.

  5. Substrate selection for fundamental studies of electrocatalysts and photoelectrodes: inert potential windows in acidic, neutral, and basic electrolyte.

    Science.gov (United States)

    Benck, Jesse D; Pinaud, Blaise A; Gorlin, Yelena; Jaramillo, Thomas F

    2014-01-01

    The selection of an appropriate substrate is an important initial step for many studies of electrochemically active materials. In order to help researchers with the substrate selection process, we employ a consistent experimental methodology to evaluate the electrochemical reactivity and stability of seven potential substrate materials for electrocatalyst and photoelectrode evaluation. Using cyclic voltammetry with a progressively increased scan range, we characterize three transparent conducting oxides (indium tin oxide, fluorine-doped tin oxide, and aluminum-doped zinc oxide) and four opaque conductors (gold, stainless steel 304, glassy carbon, and highly oriented pyrolytic graphite) in three different electrolytes (sulfuric acid, sodium acetate, and sodium hydroxide). We determine the inert potential window for each substrate/electrolyte combination and make recommendations about which materials may be most suitable for application under different experimental conditions. Furthermore, the testing methodology provides a framework for other researchers to evaluate and report the baseline activity of other substrates of interest to the broader community.

  6. Substrate selection for fundamental studies of electrocatalysts and photoelectrodes: inert potential windows in acidic, neutral, and basic electrolyte.

    Directory of Open Access Journals (Sweden)

    Jesse D Benck

    Full Text Available The selection of an appropriate substrate is an important initial step for many studies of electrochemically active materials. In order to help researchers with the substrate selection process, we employ a consistent experimental methodology to evaluate the electrochemical reactivity and stability of seven potential substrate materials for electrocatalyst and photoelectrode evaluation. Using cyclic voltammetry with a progressively increased scan range, we characterize three transparent conducting oxides (indium tin oxide, fluorine-doped tin oxide, and aluminum-doped zinc oxide and four opaque conductors (gold, stainless steel 304, glassy carbon, and highly oriented pyrolytic graphite in three different electrolytes (sulfuric acid, sodium acetate, and sodium hydroxide. We determine the inert potential window for each substrate/electrolyte combination and make recommendations about which materials may be most suitable for application under different experimental conditions. Furthermore, the testing methodology provides a framework for other researchers to evaluate and report the baseline activity of other substrates of interest to the broader community.

  7. Identification and in Vivo Evaluation of Liver X Receptor β-Selective Agonists for the Potential Treatment of Alzheimer's Disease.

    Science.gov (United States)

    Stachel, Shawn J; Zerbinatti, Celina; Rudd, Michael T; Cosden, Mali; Suon, Sokreine; Nanda, Kausik K; Wessner, Keith; DiMuzio, Jillian; Maxwell, Jill; Wu, Zhenhua; Uslaner, Jason M; Michener, Maria S; Szczerba, Peter; Brnardic, Edward; Rada, Vanessa; Kim, Yuntae; Meissner, Robert; Wuelfing, Peter; Yuan, Yang; Ballard, Jeanine; Holahan, Marie; Klein, Daniel J; Lu, Jun; Fradera, Xavier; Parthasarathy, Gopal; Uebele, Victor N; Chen, Zhongguo; Li, Yingjie; Li, Jian; Cooke, Andrew J; Bennett, D Jonathan; Bilodeau, Mark T; Renger, John

    2016-04-14

    Herein, we describe the development of a functionally selective liver X receptor β (LXRβ) agonist series optimized for Emax selectivity, solubility, and physical properties to allow efficacy and safety studies in vivo. Compound 9 showed central pharmacodynamic effects in rodent models, evidenced by statistically significant increases in apolipoprotein E (apoE) and ATP-binding cassette transporter levels in the brain, along with a greatly improved peripheral lipid safety profile when compared to those of full dual agonists. These findings were replicated by subchronic dosing studies in non-human primates, where cerebrospinal fluid levels of apoE and amyloid-β peptides were increased concomitantly with an improved peripheral lipid profile relative to that of nonselective compounds. These results suggest that optimization of LXR agonists for Emax selectivity may have the potential to circumvent the adverse lipid-related effects of hepatic LXR activity.

  8. Hillslope-channel coupling in the Nepal Himalayas and threat to man-made structures: The middle Kali Gandaki valley

    Science.gov (United States)

    Fort, M.; Cossart, E.; Arnaud-Fassetta, G.

    2010-12-01

    In mountain areas, the confinement of valleys favours landslide interaction with rivers, causing channel changes or short-lived dams and lakes that may threaten trails, roads and human settlements. Their impacts may occur successively in space and time, and they affect randomly the functioning of the sediment fluxes. The present study focuses on the interaction patterns between unstable mountain slopes and the Kali Gandaki River, in the Nepal Himalayas. In this valley, the deepest on earth, a road linking the Myagdi and Mustang districts has been under construction for the past 5 years, either cutting into the bedrock or crossing areas affected episodically by debris slides, earth flows, debris flows and rock slides. On the basis of the geomorphic evolution observed over the last three decades, we assess the potential threats that now arise following completion of the road. We mapped three areas of recurrent mass wasting features characteristic of the most frequent situations encountered in this valley. We analyzed the combination of the hydro-geomorphic processes involved. With the use of a DEM, we assessed the volume and spatial impact of temporary river dams on infrastructure located along the valley floor. We estimated hydraulic parameters to document the geomorphic efficiency of river flooding after dam breaching. We reconstructed the spatial extent of (1) areas threatened by backwater flooding upstream of the dams and (2) areas threatened by the collapse of the dams. We describe the current geomorphic and sedimentary adjustments still at work along the valley sides. Our findings confirm that in the High Himalaya, medium scale landslides (10 5-6 m 3) play a major role in the overall process of denudation and sediment transfer. They highly influence the transient nature of bedload transport in the channel. In reducing the residence time of sediments in temporary, spatially limited traps of the valley bottom, they enhance the vulnerability of land and people

  9. Canola Cake as a Potential Substrate for Proteolytic Enzymes Production by a Selected Strain of Aspergillus oryzae: Selection of Process Conditions and Product Characterization

    Science.gov (United States)

    Freitas, Adriana C.; Castro, Ruann J. S.; Fontenele, Maria A.; Egito, Antonio S.; Farinas, Cristiane S.; Pinto, Gustavo A. S.

    2013-01-01

    Oil cakes have excellent nutritional value and offer considerable potential for use in biotechnological processes that employ solid-state fermentation (SSF) for the production of high value products. This work evaluates the feasibility of using canola cake as a substrate for protease production by a selected strain of Aspergillus oryzae cultivated under SSF. The influences of the following process parameters were considered: initial substrate moisture content, incubation temperature, inoculum size, and pH of the buffer used for protease extraction and activity analysis. Maximum protease activity was obtained after cultivating Aspergillus oryzae CCBP 001 at 20°C, using an inoculum size of 107 spores/g in canola cake medium moistened with 40 mL of water to 100 g of cake. Cultivation and extraction under selected conditions increased protease activity 5.8-fold, compared to the initial conditions. Zymogram analysis of the enzymatic extract showed that the protease molecular weights varied between 31 and 200 kDa. The concentrated protease extract induced clotting of casein in 5 min. The results demonstrate the potential application of canola cake for protease production under SSF and contribute to the technological advances needed to increase the efficiency of processes designed to add value to agroindustrial wastes. PMID:24455400

  10. Phalaris canariensis L. (Poaceae: A new alien plant record for Kashmir Himalaya, India

    Directory of Open Access Journals (Sweden)

    Shugufta Rasheed

    2016-03-01

    Full Text Available The correct taxonomic identification assumes first and foremost priority in the scientific documentation of biodiversity. The Kashmir Himalaya, located in the north-western side of the Himalayan biodiversity hotspot, is well-known for its diverse flora which merits immediate scientific documentation. In this context, the present study reports Phalaris canariensis L. (Poaceae as a new alien plant record to the flora of Kashmir Himalaya, India. In this paper, a detailed description, photographs, and comparison of diagnostic characters with allied species are provided to scientifically validate this alien plant record for this Himalayan region.

  11. Events of abrupt change ofIndian monsoon recorded in Dasuopu ice core fromHimalayas

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Three ice cores distributed across Dasuopu glacier in Himalayas were recovered. A 400-year net annual accumulation record reconstructed from one of the cores reflects the major precipitation trend in the central Himalayas. This record is related closely to the Indian monsoon precipitation. Wavelet and moving T-test were applied to the 400-year-long Dasuopu accumulation record, and significant staggered variability and abrupt change of the record on interannual to centennial time scales are identified. Finally the possible reason for abrupt change of the accumulation record is discussed.

  12. New Mycomya species from the Himalayas (Diptera, Mycetophilidae): 3. Subgenera Cesamya and Mycomyopsis.

    Science.gov (United States)

    Väisänen, Rauno

    2013-11-19

    Mycomya Rondani specimens from the Himalayas, mostly Nepal and Myanmar, are revised. Altogether four species of the subgenus Cesamya Koçak & Kemal and eleven species of the subgenus Mycomyopsis Väisänen are recorded from the Himalayas and the Indian subcontinent. The paper includes a key to the Himalayan species of Mycomya of the two subgenera. The following fourteen new species are described: M. aix, M. alticola, M. banteng, M. cissa, M. ducula, M. irena, M. goral, M. jeti, M. kaa, M. naja, M. niltava, M. pitta, M. sachak, and M. sanar. The holotype of M. unipectinata Edwards from Sri Lanka was also examined and its genitalia are described.

  13. Interactions of biotic and abiotic environmental factors in an ectomycorrhizal symbiosis, and the potential for selection mosaics

    Directory of Open Access Journals (Sweden)

    Hoeksema Jason D

    2008-05-01

    Full Text Available Abstract Background Geographic selection mosaics, in which species exert different evolutionary impacts on each other in different environments, may drive diversification in coevolving species. We studied the potential for geographic selection mosaics in plant-mycorrhizal interactions by testing whether the interaction between bishop pine (Pinus muricata D. Don and one of its common ectomycorrhizal fungi (Rhizopogon occidentalis Zeller and Dodge varies in outcome, when different combinations of plant and fungal genotypes are tested under a range of different abiotic and biotic conditions. Results We used a 2 × 2 × 2 × 2 factorial experiment to test the main and interactive effects of plant lineage (two maternal seed families, fungal lineage (two spore collections, soil type (lab mix or field soil, and non-mycorrhizal microbes (with or without on the performance of plants and fungi. Ecological outcomes, as assessed by plant and fungal performance, varied widely across experimental environments, including interactions between plant or fungal lineages and soil environmental factors. Conclusion These results show the potential for selection mosaics in plant-mycorrhizal interactions, and indicate that these interactions are likely to coevolve in different ways in different environments, even when initially the genotypes of the interacting species are the same across all environments. Hence, selection mosaics may be equally as effective as genetic differences among populations in driving divergent coevolution among populations of interacting species.

  14. Potential-scour assessments and estimates of maximum scour at selected bridges in Iowa

    Science.gov (United States)

    Fischer, E.E.

    1995-01-01

    The results of potential-scour assessments at 130 bridges and estimates of maximum scour at 10 bridges in Iowa are presented. All of the bridges evaluated in the study are constructed bridges (not culverts) that are sites of active or discontinued streamflow-gaging stations and peak-stage measurement sites. The period of the study was from October 1991 to September 1994.

  15. Development of live attenuated Streptococcus agalactiae as potential vaccines by selecting for resistance to sparfloxacin

    Science.gov (United States)

    To develop attenuated bacteria as potential live vaccines, sparfloxacin was used in this study to modify 40 isolates of Streptococcus agalactiae. Majority of S. agalactiae used in this study were able to develop at least 80-fold resistance to sparfloxacin. When the virulence of the sparfloxacin-resi...

  16. Response of Glacier and Lake Dynamics in Four Inland Basins to Climate Change at the Transition Zone between the Karakorum And Himalayas.

    Directory of Open Access Journals (Sweden)

    Zhiguo Li

    Full Text Available Inland glacier and lake dynamics on the Tibetan Plateau (TP and its surroundings over recent decades are good indicators of climate change and have a significant impact on the local water supply and ecosystem. The glacier and lake changes in Karakoram are quite different from those of the Himalayas. The mechanisms of the complex and regionally heterogeneous behavior of the glacier and lake changes between the Karakorum and Himalayas are poorly understood. Based on satellite images and meteorological data of Shiquanhe, Hetian, and Yutian stations, we demonstrate that the overall retreat of glaciers and increase of lake area at the transition zone between the Karakoram and Himalayas (TKH have occurred since 1968 in response to a significant global climate change. Glacial areas in the Songmuxi Co basin, Zepu Co basin, Mang Co basin and Unnamed Co decreased by -1.98 ± 0.02 km2, -5.39 ± 0.02 km2, -0.01 ± 0.02 km2, and -0.12 ± 0.02 km2 during the study period, corresponding to losses of -1.42%, -2.86%, -1.54%, and -1.57%, respectively. The lake area of the Songmuxi Co, Zepu Co, Mang Co and Unnamed Co increased by 7.57 ± 0.02 km2, 8.53 ± 0.02 km2, 1.35 ± 0.02 km2, and 0.53 ± 0.02 km2, corresponding to growths of 30.22%, 7.55%, 11.39%, and 8.05%, respectively. Increases in temperature was the main reason for glacier retreat, whereas decreases in potential evapotranspiration of lakes, increases in precipitation, and increases in melt water from glaciers and frozen soil all contributed to lake area expansion.

  17. Relation between methanogenic archaea and methane production potential in selected natural wetland ecosystems across China

    Science.gov (United States)

    Liu, D. Y.; Ding, W. X.; Jia, Z. J.; Cai, Z. C.

    2011-02-01

    Methane (CH4) emissions from natural wetland ecosystems exhibit large spatial variability at regional, national, and global levels related to temperature, water table, plant type and methanogenic archaea etc. To understand the underlying factors that induce spatial differences in CH4 emissions, and the relationship between the population of methanogenic archaea and CH4 production potential in natural wetlands around China, we measured the CH4 production potential and the abundance of methanogenic archaea in vertical soil profiles sampled from the Poyang wetland in the subtropical zone, the Hongze wetland in the warm temperate zone, the Sanjiang marsh in the cold temperate zone, and the Ruoergai peatland in the Qinghai-Tibetan Plateau in the alpine climate zone. The top soil layer had the highest population of methanogens (1.07-8.29 × 109 cells g-1 soil) in all wetlands except the Ruoergai peatland and exhibited the maximum CH4 production potential measured at the mean in situ summer temperature. There is a significant logarithmic correlation between the abundance of methanogenic archaea and the soil organic carbon (R2 = 0.72, P nitrogen concentrations (R2 = 0.76, P affect the population of methanogens in wetland ecosystems. While the CH4 production potential is not significantly related to methanogen population (R2 = 0.01, P > 0.05, n = 13), it is related to the dissolved organic carbon concentration (R2 = 0.31, P = 0.05, n = 13). This suggests that the methanogen population might be not an effective index for predicting the CH4 production in wetland ecosystems. The CH4 production rate of the top soil layer increases with increasing latitude, from 273.64 μg CH4 kg-1 soil d-1 in the Poyang wetland to 664.59 μg CH4 kg-1 soil d-1 in the Carex lasiocarpa marsh of the Sanjiang Plain. We conclude that CH4 production potential in the freshwater wetlands of Eastern China is mainly affected by the supply of methanogenic substrates rather than temperature; in contrast

  18. Recording strategies and selection potential of feed intake measured using the X-ray method in rainbow trout

    Directory of Open Access Journals (Sweden)

    Mäntysaari Esa A

    2006-06-01

    Full Text Available Abstract This study examines the way long-term feed intake should be recorded accurately for selective breeding purposes, and estimates selection potential in feed intake using the X-ray method to record individual daily feed intake in rainbow trout (Oncorhynchus mykiss. The analysis showed that the point estimates of daily feed intake displayed low repeatabilities (r = 0.09–0.32. This indicates that a minimum of three repeated records were needed to accurately record average feed intake at a fixed age. To effectively breed for feed intake over the whole growing period, it is necessary to determine average feed intake at different ages, since there were only moderate phenotypic and genetic correlations between average daily feed intake recorded at 140 g, 750 g and 2000 g wet mass. Heritability for average daily feed intake was low (average h2 = 0.10, indicating that modest genetic changes can be obtained in response to selection. It was concluded that selection to genetically change long-term feed intake can be successful, yet repeated observations at several life stages are needed to ensure the accuracy of feed intake estimates and the efficiency of selection.

  19. Strategies for the evaluation and selection of potential vaginal probiotics from human sources: an exemplary study.

    Science.gov (United States)

    Domig, K J; Kiss, H; Petricevic, L; Viernstein, H; Unger, F; Kneifel, W

    2014-09-01

    During the last years, the application of probiotics in gynaecological clinical practice has gained increasing relevance regarding therapy and prevention. This trend has also provoked the need for having tailored pharmaceutical preparations containing powerful microbial strains with defined properties. For the development of such preparations, several factors and criteria have to be considered, thereby not only focusing on identity and safety aspects as well as individual properties of the bacterial strains, but also on technological issues, such as stability and targeted release from the preparation. Against this background, this report exemplarily addresses the development procedure of a probiotic bacterial formulation for gynaecological application, covering the search for suitable strains, assessing their microbiological, molecular biological and physiological characterisation, and the selection for their use in clinical trials. In detail, starting with 127 presumptive lactobacilli isolates of vaginal origin, a step-by-step selection of candidate strains meeting special criteria was thoroughly examined, finally leading to a preparation consisting of four individual Lactobacillus strains that possess particular significance in women's urogenital health. Relevant issues and quality criteria of probiotic preparations used in gynecology are addressed and exemplarily introduced.

  20. Identification and Characterization of Genes Involved in Leishmania Pathogenesis: The Potential for Drug Target Selection

    Directory of Open Access Journals (Sweden)

    Robert Duncan

    2011-01-01

    Full Text Available Identifying and characterizing Leishmania donovani genes and the proteins they encode for their role in pathogenesis can reveal the value of this approach for finding new drug targets. Effective drug targets are likely to be proteins differentially expressed or required in the amastigote life cycle stage found in the patient. Several examples and their potential for chemotherapeutic disruption are presented. A pathway nearly ubiquitous in living cells targeted by anticancer drugs, the ubiquitin system, is examined. New findings in ubiquitin and ubiquitin-like modifiers in Leishmania show how disruption of those pathways could point to additional drug targets. The programmed cell death pathway, now recognized among protozoan parasites, is reviewed for some of its components and evidence that suggests they could be targeted for antiparasitic drug therapy. Finally, the endoplasmic reticulum quality control system is involved in secretion of many virulence factors. How disruptions in this pathway reduce virulence as evidence for potential drug targets is presented.

  1. Energy Efficiency Potential in Existing Commercial Buildings: Review of Selected Recent Studies

    Energy Technology Data Exchange (ETDEWEB)

    Belzer, David B.

    2009-04-03

    This report reviews six recent studies (from 2002 through 2006) by states and utilities to assess the energy saving potential in existing commercial buildings. The studies cover all or portions of California, Connecticut, Vermont, Colorado, Illinois, and the Pacific Northwest. The studies clearly reveal that lighting remains the single largest and most cost effective end use that can be reduced to save energy. Overall the study indicated that with existing technologies and costs, a reasonable range of economic savings potential in existing commercial buildings is between 10 and 20 percent of current energy use. While not a focus of the study, an additional conclusion is that implementation of commercial building monitoring and controls would also play an important role in the nation’s efforts to improve energy efficiency of existing buildings.

  2. Active prey selection in two pelagic copepods feeding on potentially toxic and non-toxic dinoflagellates

    DEFF Research Database (Denmark)

    Schultz, Mette; Kiørboe, Thomas

    2009-01-01

    Grazing on two red tide dinoflagellates, the potentially toxic Karenia mikimotoi and the non-toxic Gyrodinium instriatum, was examined in two species of marine copepods, Pseudocalanus elongatus and Temora longicornis. Both copepods cleared K. mikimotoi at rates that were a little lower but compar......Grazing on two red tide dinoflagellates, the potentially toxic Karenia mikimotoi and the non-toxic Gyrodinium instriatum, was examined in two species of marine copepods, Pseudocalanus elongatus and Temora longicornis. Both copepods cleared K. mikimotoi at rates that were a little lower...... but comparable to those at which they cleared the slightly larger G. instriatum when the two dinoflagellates were offered separately. However, when feeding on mixtures of the two prey species, the clearance rates on K. mikimotoi were substantially reduced in both copepods while their clearances of G. instiatum...

  3. Selection of potential probiotic Enterococcus faecium isolated from Portuguese fermented food.

    Science.gov (United States)

    Barbosa, Joana; Borges, Sandra; Teixeira, Paula

    2014-11-17

    Four Enterococcus faecium strains isolated from fermented products were evaluated for potential use as probiotic strains. In addition to efaAfm gene, commonly found in E. faecium food isolates, none of the isolates possessed virulence genes and none had positive reactions for the production of tyramine, histamine, putrescine and cadaverine in the screening medium used. All of these four isolates proved to be resistant to 65 °C. E. faecium 119 did not show antimicrobial activity against any of the target bacteria investigated. E. faecium 85 and 101 inhibited Listeria innocua and E. faecium DSMZ 13590. The strain E. faecium 120 inhibited seven target bacteria (Listeria monocytogenes 7946, L. monocytogenes 7947, L. innocua 2030c, L. innocua NCTC 11286, E. faecium DSMZ 13590, Enterococcus faecalis ATCC 29212 and Staphylococcus aureus ATCC 29213) and was chosen as the representative to assess the ability to survive gastrointestinal tract passage simulation, as well as the protective role of two food matrices (skim milk and Alheira) during its passage. For both matrices used, no significant differences (pdetection limit of the enumeration technique by the end of the two digestions, in contrast to the Alheira matrix, for which isolate 120 showed a reduction of only ca. 1 log CFU/ml. The E. faecium strain 120 was shown to be a potential candidate for further investigations as a potential probiotic culture.

  4. Comparative Assessment Of Coastal Tourism Potentials Of Selected Areas In Rivers State Nigeria

    Directory of Open Access Journals (Sweden)

    Obinwanne

    2015-08-01

    Full Text Available ABSTRACT The study examined coastal tourism potentials in Rivers State with emphasis on Opobo Bonny and Port Harcourt to determine the area that has comparative advantage for tourism development to optimally utilize resources. The study was conducted in Bonny Opobo and Port Harcourt of River State Nigeria. The area occupies the land close to the Atlantic Ocean within 60km radius from the coast. A survey design was adopted for the study. The instruments used were observation checklist and interview schedule. The instruments were tested for validity and reliability using five experts drawn from the field. The data collected were analyzed using ethnographic description method of analysis to answer research questions. The natural attractions found include mangrove forest sacred forests sacred rivers lakes beaches fishing rivers natural sources of drinking water and sanctuary. The cultural heritage resources were historical monument shrines museums different cultural festivals cultural materials and slave port. The man-made attractions were recreational park zoological garden and tourism village. It was found that there were more tourism potentials in Port Harcourt study site more than Bonny and Opobo sites and therefore Port Harcourt has comparative advantage over Bonny and Opobo for tourism development. Therefore efforts should be made and scarce resources utilized towards developing those coastal areas with best potentials and comparative advantage over others.

  5. The method of assessment of solar potential for selected area with use Geographical Information Systems

    Directory of Open Access Journals (Sweden)

    Netzel P.

    2012-10-01

    Full Text Available This paper describes a method for analyse the spatial distribution of solar energy potential based on calculated solar irradiation with use of GIS (Geographical Information System. Program GIS GRASS gives opportunity to create spatial distribution of solar radiation which is taking into account such important elements like: terrain, atmosphere, pollutants, water and aerosol in atmosphere, clouds. The use of GIS GRASS module – named r.sun gives opportunity to generate spatial distribution of solar radiation on Lower Silesia (south – west part of Poland. In this work the analyse of solar potential to obtain hot water in the individual household were done. This analyse was based on the amount of total solar radiation monthly sums generated by r.sun module. Spatial distribution of solar potential was used to classify the Lower Silesia region in terms of work efficiency solar installations. It is very usefully because it gives people information about the date of the return of the funds invested in the purchase of the solar collectors.

  6. Atmospheric aerosol brown carbon in the high Himalayas

    Science.gov (United States)

    Kirillova, Elena; Decesari, Stefano; Marinoni, Angela; Bonasoni, Paolo; Vuillermoz, Elisa; Facchini, M. Cristina; Fuzzi, Sandro

    2016-04-01

    Anthropogenic light-absorbing atmospheric aerosol can reach very high concentrations in the planetary boundary layer in South-East Asia ("brown clouds"), affecting atmospheric transparency and generating spatial gradients of temperature over land with a possible impact on atmospheric dynamics and monsoon circulation. Besides black carbon (BC), an important light-absorbing component of anthropogenic aerosols is the organic carbon component known as 'brown carbon' (BrC). In this research, we provided first measurements of atmospheric aerosol BrC in the high Himalayas during different seasons. Aerosol sampling was conducted at the GAW-WMO Global station "Nepal Climate Observatory-Pyramid" (NCO-P) located in the high Khumbu valley at 5079 m a.s.l. in the foothills of Mt. Everest. PM10 aerosol samples were collected from July 2013 to November 2014. The sampling strategy was set up in order to discriminate the daytime valley breeze bringing polluted air masses up to the observatory and free tropospheric air during nighttime. Water-soluble BrC (WS-BrC) and methanol-soluble BrC (MeS-BrC) were extracted and analyzed using a UV/VIS spectrophotometer equipped with a 50 cm liquid waveguide capillary cell. In the polluted air masses, the highest levels of the BrC light absorption coefficient at 365 nm (babs365) were observed during the pre-monsoon season (1.83±1.46 Mm-1 for WS-BrC and 2.86±2.49 Mm-1 for MeS-BrC) and the lowest during the monsoon season (0.21±0.22 Mm-1 for WS-BrC and 0.32±0.29 Mm-1 for MeS-BrC). The pre-monsoon season is the most frequently influenced by a strong atmospheric brown cloud (ABC) transport to NCO-P due to increased convection and mixing layer height over South Asia combined with the highest up-valley wind speed and the increase of the emissions from open fires due to the agricultural practice along the Himalayas foothills and the Indo-Gangetic Plain. In contrast, the monsoon season is characterized by a weakened valley wind regime and an

  7. Proceedings of the 25th Himalaya-Karakoram-Tibet Workshop

    Science.gov (United States)

    Leech, Mary L.; Klemperer, Simon L.; Mooney, Walter D.

    2010-01-01

    For a quarter of a century the Himalayan-Karakoram-Tibet (HKT) Workshop has provided scientists studying the India-Asia collision system a wonderful opportunity for workshop-style discussion with colleagues working in this region. In 2010, HKT returns to North America for the first time since 1996. The 25th international workshop is held from June 7 to10 at San Francisco State University, California. The international community was invited to contribute scientific papers to the workshop, on all aspects of geoscience research in the geographic area of the Tibetan Plateau and its bounding ranges and basins, from basic mapping to geochemical and isotopic analyses to large-scale geophysical imaging experiments. In recognition of the involvement of U.S. Geological Survey (USGS) scientists in a wide range of these activities, the USGS agreed to publish the extended abstracts of the numerous components of HKT-25 as an online Open-File Report, thereby ensuring the wide availability and distribution of these abstracts, particularly in the HKT countries from which many active workers are precluded by cost from attending international meetings. In addition to the workshop characterized by contributed presentations, participants were invited to attend a pre-meeting field trip from the Coast Ranges to the Sierra Nevada, to allow the international group to consider how the tectonic elements of the Pacific margin compare to those of the Himalayan belt. Following the workshop, the National Science Foundation (NSF) sponsored a workshop on the 'Future directions for NSF-sponsored geoscience research in the Himalaya/Tibet' intended to provide NSF Program Directors with a clear statement and vision of community goals for the future, including the scientific progress we can expect if NSF continues its support of projects in this geographic region, and to identify which key geoscience problems and processes are best addressed in the Himalaya and Tibet, what key datasets are needed, and

  8. Diversity of Medicinal Plants among Different Forest-use Types of the Pakistani Himalaya.

    Science.gov (United States)

    Adnan, Muhammad; Hölscher, Dirk

    2012-12-01

    Diversity of Medicinal Plants among Different Forest-use Types of the Pakistani Himalaya Medicinal plants collected in Himalayan forests play a vital role in the livelihoods of regional rural societies and are also increasingly recognized at the international level. However, these forests are being heavily transformed by logging. Here we ask how forest transformation influences the diversity and composition of medicinal plants in northwestern Pakistan, where we studied old-growth forests, forests degraded by logging, and regrowth forests. First, an approximate map indicating these forest types was established and then 15 study plots per forest type were randomly selected. We found a total of 59 medicinal plant species consisting of herbs and ferns, most of which occurred in the old-growth forest. Species number was lowest in forest degraded by logging and intermediate in regrowth forest. The most valuable economic species, including six Himalayan endemics, occurred almost exclusively in old-growth forest. Species composition and abundance of forest degraded by logging differed markedly from that of old-growth forest, while regrowth forest was more similar to old-growth forest. The density of medicinal plants positively correlated with tree canopy cover in old-growth forest and negatively in degraded forest, which indicates that species adapted to open conditions dominate in logged forest. Thus, old-growth forests are important as refuge for vulnerable endemics. Forest degraded by logging has the lowest diversity of relatively common medicinal plants. Forest regrowth may foster the reappearance of certain medicinal species valuable to local livelihoods and as such promote acceptance of forest expansion and medicinal plants conservation in the region. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s12231-012-9213-4) contains supplementary material, which is available to authorized users.

  9. Citizen Science in the Himalaya: The Sherpa-Scientist Initiative

    Science.gov (United States)

    Horodyskyj, U. N.; Breashears, D.; Rowe, P.

    2015-12-01

    Since the non-profit educational group, Black Ice Himalaya, launched in 2011 our goal has been to involve local communities in our research expeditions, in the form of a Sherpa-Scientist Initiative (SSI). This goes beyond simply helping with gear carries to research sites. It involves training the local Sherpa in equipment set-up, data collection, and analysis processes, with the goal of turning over this task to local communities and villages in the future. As the terrain continues to change - with the growth and expansion of glacial lakes, along with accumulation of pollutants on snow at higher altitudes - this training program presents an excellent opportunity for long-term data collection in sensitive alpine regions. In association with GlacierWorks and Midwest ROV LLC, skill training has included gigapan high-resolution photography, installing (and downloading) multiple time lapse cameras to track hour-by-hour glacial lake changes; lake bathymetry mapping using side-scan sonar from an unmanned towed platform; installing and managing weather stations; collecting and analyzing data from ASD field spectrometers; and collecting/filtering snow samples to look for contaminants (pollutants) affecting snow melt from 4000 - 6000 meters. A field manual documenting this work and intended to raise awareness of glacial trekking hazards has been disseminated to the International Centre for Integrated Mountain Development (ICIMOD) and Sagarmatha (Everest) National Park. In 2016-17, in collaboration with Vanguard Diving and Exploration, OpenROV, and Midwest ROV LLC, efforts will include SCUBA diving into glacial lakes to collect scientific data, with continued Sherpa training on how to assemble and use portable remotely piloted submersibles to aid in the assessment of glacial lake hazards.

  10. Petrogenesis and tectonic implications of the Yadong leucogranites, southern Himalaya

    Science.gov (United States)

    Gou, Zhengbin; Zhang, Zeming; Dong, Xin; Xiang, Hua; Ding, Huixia; Tian, Zuolin; Lei, Hengcong

    2016-07-01

    The leucogranites in the Higher Himalayan Sequence (HHS) provide a probe to elucidate the crustal melting of continental collisional orogen. An integrated geochemical and geochronological study of the Yadong leucogranites, southern Himalaya, shows that these rocks have relatively high SiO2 contents of 69.77 to 75.32 wt.% and alumina saturation index (A/CNK) of 1.09-1.40, typical of peraluminous granites. They show moderately fractionated REE patterns with negative Eu anomalies, and are characterized by enriched LILE (Rb and Cs) and depleted HFSE (Zr, Hf, Nb and Ta). LA-ICP-MS U-Pb zircon dating of ten samples yields crystallization ages ranging from 21.0 to 11.7 Ma. The zircons have variable εHf(t) values of - 26.3 to - 3.5 and corresponding Hf two-stage model ages of 2.77-1.33 Ga. The present study reveals that the muscovite-biotite leucogranites (2ML) have higher TiO2, MgO, CaO, Sr, Ba and Zr contents, lower Rb/Sr ratios than the tourmaline-muscovite leucogranites (TML). Zircon and monazite saturation thermometry results show that the melt temperatures (681-784 °C) of the 2ML are 20-80 °C higher than those (663-705 °C) of the TML. Combining with previous results, we propose that the TML were derived from the muscovite-dehydration melting, whereas the 2ML dominantly resulted from the biotite-dehydration melting during the prograde metamorphism of the pelitic and felsic granulites of the HHS. Therefore, the Himalayan leucogranites were probably formed during the subduction of the Indian crust following the India and Asia collision.

  11. Selective attention in the presence of music: an event-related potentials (ERP) study.

    Science.gov (United States)

    Dalbokova, D; Kolev, P; Kristeva, R

    1988-06-01

    The present study was aimed at investigating selective attention in the presence of music as expressed by ERPs. The experiments were performed with 7 subjects. A two-channel auditory frequency discrimination task (target - 1000 Hz, standard - 1550 Hz tones) in a dichotic listening environment was employed. The EEG was recorded from Fz, Cz, Pz, C3 and C4. The EOG and performance data were also collected. A smaller and delayed N1 amplitude as well as changes in the two components of the processing negativity in the presence of music were found. N2 and P3 components only delay with music was observed. The changes in the level of performance were not significant.

  12. Perils and potentials of self-selected entry to epidemiological studies and surveys

    DEFF Research Database (Denmark)

    Keiding, Niels; Louis, Thomas A.

    2016-01-01

    Low front-end cost and rapid accrual make Web-based surveys and enrolment in studies attractive, but participants are often self-selected with little reference to a well-defined study base. Of course, high quality studies must be internally valid (validity of inferences for the sample at hand......), but Web-based enrolment reactivates discussion of external validity (generalization of within-study inferences to a target population or context) in epidemiology and clinical trials. Survey research relies on a representative sample produced by a sampling frame, prespecified sampling process and weighting...... that maps results to an intended population. In contrast, recent analytical epidemiology has shifted the focus away from survey-type representativity to internal validity in the sample. Against this background, it is a good time for statisticians to take stock of our role and position regarding surveys...

  13. Cultivar variation and selection potential relevant to the production of cellulosic ethanol from wheat straw

    DEFF Research Database (Denmark)

    Lindedam, Jane; Andersen, Sven Bode; DeMartini, J.;

    2012-01-01

    -plate technique. This technique enabled us to estimate cultivar-related and environmental correlations between sugar yield, chemical composition, agronomic qualities, and distribution of botanical plant parts of wheat straw cultivars. Straws from 20 cultivars were collected in duplicates on two sites in Denmark......Optimizing cellulosic ethanol yield depends strongly on understanding the biological variation of feedstocks. Our objective was to study variation in capacity for producing fermentable sugars from straw of winter wheat cultivars with a high-throughput pretreatment and hydrolysis well...... suggest that selection of cultivars for improved biofuel feedstock of wheat straw is possible, because heritability of sugar release is 57% and there are few adverse correlations to other agronomic traits....

  14. Visual encoding and fixation target selection in free viewing: presaccadic brain potentials

    Science.gov (United States)

    Nikolaev, Andrey R.; Jurica, Peter; Nakatani, Chie; Plomp, Gijs; van Leeuwen, Cees

    2013-01-01

    In scrutinizing a scene, the eyes alternate between fixations and saccades. During a fixation, two component processes can be distinguished: visual encoding and selection of the next fixation target. We aimed to distinguish the neural correlates of these processes in the electrical brain activity prior to a saccade onset. Participants viewed color photographs of natural scenes, in preparation for a change detection task. Then, for each participant and each scene we computed an image heat map, with temperature representing the duration and density of fixations. The temperature difference between the start and end points of saccades was taken as a measure of the expected task-relevance of the information concentrated in specific regions of a scene. Visual encoding was evaluated according to whether subsequent change was correctly detected. Saccades with larger temperature difference were more likely to be followed by correct detection than ones with smaller temperature differences. The amplitude of presaccadic activity over anterior brain areas was larger for correct detection than for detection failure. This difference was observed for short “scrutinizing” but not for long “explorative” saccades, suggesting that presaccadic activity reflects top-down saccade guidance. Thus, successful encoding requires local scanning of scene regions which are expected to be task-relevant. Next, we evaluated fixation target selection. Saccades “moving up” in temperature were preceded by presaccadic activity of higher amplitude than those “moving down”. This finding suggests that presaccadic activity reflects attention deployed to the following fixation location. Our findings illustrate how presaccadic activity can elucidate concurrent brain processes related to the immediate goal of planning the next saccade and the larger-scale goal of constructing a robust representation of the visual scene. PMID:23818877

  15. Visual encoding and fixation target selection in free viewing: presaccadic brain potentials

    Directory of Open Access Journals (Sweden)

    Andrey R Nikolaev

    2013-06-01

    Full Text Available In scrutinizing a scene, the eyes alternate between fixations and saccades. During a fixation, two component processes can be distinguished: visual encoding and selection of the next fixation target. We aimed to distinguish the neural correlates of these processes in the electrical brain activity prior to a saccade onset. Participants viewed color photographs of natural scenes, in preparation for a change detection task. Then, for each participant and each scene we computed an image heat map, with temperature representing the duration and density of fixations. The temperature difference between the start and end points of saccades was taken as a measure of the expected task-relevance of the information concentrated in specific regions of a scene. Visual encoding was evaluated according to whether subsequent change was correctly detected. Saccades with larger temperature difference were more likely to be followed by correct detection than ones with smaller temperature differences. The amplitude of presaccadic activity over anterior brain areas was larger for correct detection than for detection failure. This difference was observed for short scrutinizing but not for long explorative saccades, suggesting that presaccadic activity reflects top-down saccade guidance. Thus, successful encoding requires local scanning of scene regions which are expected to be task-relevant. Next, we evaluated fixation target selection. Saccades moving up in temperature were preceded by presaccadic activity of higher amplitude than those moving down. This finding suggests that presaccadic activity reflects attention deployed to the following fixation location. Our findings illustrate how presaccadic activity can elucidate concurrent brain processes related to the immediate goal of planning the next saccade and the larger-scale goal of constructing a robust representation of the visual scene.

  16. Out-of-Sequence Thrust in the Higher Himalaya- a Review & Possible Genesis

    Science.gov (United States)

    Mukherjee, S.; Koyi, H. A.; Talbot, C. J.

    2009-04-01

    An out-of-sequence thrust (OOST) has been established inside the Higher Himalaya by previous workers more frequently from Nepal- and Bhutan Himalaya. The OOST lies between the South Tibetan Detachment System-Upper (STDSU) and the South Tibetan Detachment System-Lower (STDSL). The thrust has been recognized as the Kakhtang Thrust in Bhutan (Grujic et al., 2002 and references therein); Khumbu Thrust (Searle, 1999), Modi Khola Shear Zone (Hodges et al., 1996), Kalopani Shear Zone (Vannay and Hodges, 1999), Toijem Shear Zone in Nepal (Carosi et al., 2007), Chaura Thrust (Jain et al., 2000)- also designated as the Sarahan Thrust (Chambers et al., 2008) in the western Indian Himalaya in Sutlej section, Zimithang Thrust in the eastern Indian Himalaya (Yin et al., 2006), as ‘physiographic transition' in Marsyandi valley, Nepal (Burbank et al., 2003). We note that considering the upper strand of the Main Central Thrust (the MCTU) as the lower boundary of the Higher Himalaya, the physiographic transition has also been referred to lie in the Lesser Himalaya.The period of activity of the OOST was 22.5-18.5 Ma (Hodges et al., 1996), 14-10 Ma (Grujic et al., 2002), 4.9-1.5 Ma (Jain et al., 2000), and from Late Pliocene to even Holocene Period (Burbank, 2005). The out-of-sequence thrusting was followed after the initiation of channel flow at ~ 15 Ma in the Higher Himalaya with a maximum delay of ~ 13 Ma. However, in the Bhutan Himalaya, the thrusting continued along with the extensional ductile shearing in the STDSU at 11-10 Ma (Hollister and Grujic, 2006). The OOST in the Higher Himalaya lies inside the zone of the top-to-SW sense of ductile shearing. The OOST, at Kakhtang, Toijem, and Chaura are ductile shear zones with a top-to-SW sense of shearing. The OOST merges with the MCT and the Main Himalayan Thrust (MHT) at a depth of 30 km or more and either runs 200-300 km beneath the Tibetan plateau (Grujic et al., 2002; Hollister and Grujic, 2006). The hanging wall side of the

  17. Relation between methanogenic archaea and methane production potential in selected natural wetland ecosystems across China

    Directory of Open Access Journals (Sweden)

    D. Y. Liu

    2011-02-01

    Full Text Available Methane (CH4 emissions from natural wetland ecosystems exhibit large spatial variability at regional, national, and global levels related to temperature, water table, plant type and methanogenic archaea etc. To understand the underlying factors that induce spatial differences in CH4 emissions, and the relationship between the population of methanogenic archaea and CH4 production potential in natural wetlands around China, we measured the CH4 production potential and the abundance of methanogenic archaea in vertical soil profiles sampled from the Poyang wetland in the subtropical zone, the Hongze wetland in the warm temperate zone, the Sanjiang marsh in the cold temperate zone, and the Ruoergai peatland in the Qinghai-Tibetan Plateau in the alpine climate zone. The top soil layer had the highest population of methanogens (1.07–8.29 × 109 cells g−1 soil in all wetlands except the Ruoergai peatland and exhibited the maximum CH4 production potential measured at the mean in situ summer temperature. There is a significant logarithmic correlation between the abundance of methanogenic archaea and the soil organic carbon (R2 = 0.72, P < 0.001, n = 13 and between the abundance of methanogenic archaea and the total nitrogen concentrations (R2 = 0.76, P < 0.001, n = 13 in wetland soils. This indicates that the amount of soil organic carbon may affect the population of methanogens in wetland ecosystems. While the CH4 production potential is not significantly related to methanogen population (R2 = 0.01, P > 0.05, n = 13, it is related to the dissolved organic carbon concentration (R2 = 0.31, P = 0.05, n = 13. This suggests that the methanogen population might be not an effective index for predicting the CH4 production in wetland

  18. Natural selection among Kinnaura of the Himalayan highland: A comparative analysis with other Indian and Himalayan populations.

    Science.gov (United States)

    Gautam, Rajesh K; Kapoor, Anup K; Kshatriya, G K

    2009-09-01

    The present investigation on fertility and mortality differential among Kinnaura of the Himalayan highland is based on data collected from 160 post-menopausal women belonging to the middle and high altitude region of Kinnaur district of Himachal Pradesh (Indian Himalayas). Selection potential based on differential fertility and mortality was computed for middle-and high-altitude women. Irrespective of the methodology, the total index of selection was found to be highest among middle-altitude women (0.386) as compared with high-altitude (0.370) women, whereas for the total population it is estimated to be 0.384. It was found that the Kinnaura of the Himalayan highland showing moderate index of total selection and relative contribution of the mortality component (Im) to the index of total selection is higher than the corresponding fertility component (If). The analysis of embryonic and post-natal mortality components shows that the post-natal mortality components are higher in comparison with the embryonic mortality components among highlanders and needs special intervention and health care. The present findings are compared with other Indian tribes as well as non-tribes of the Himalayan region and other parts of the country. It reveals that this index among Kinnaura is moderate than the other population groups; among the Himalayan population, the highest was reported for Galong (It = 1.07) of Arunachal, whereas the lowest was reported from Ahom (It = 0.218) of Manipur. The correlation and regression analysis between total index of selection (It) and fertility (If) and mortality (Im) components for pooled data of populations of the Indian Himalayan states show that If and Im account for 21.6 and 29.1% variability, respectively. In Crow's total index of selection (It) along with strong association, which is significant at the 1% level, this indicates that mortality plays a greater role in natural selection in comparison with fertility among populations of the Indian

  19. Energy performance contracting - energy saving potential of selected energy conservation measures (ECM)

    Energy Technology Data Exchange (ETDEWEB)

    Johansson, M. (Dansk Energi Analyse A/S, Frederiksberg (Denmark)); Langkilde, G.; Olesen, Bjarne W. (Technical Univ. of Denmark, ICIEE, Kgs. Lyngby (Denmark)); Moerck, O. (Cenergia Energy Consultants, Herlev (Denmark)); Sundman, O. (DONG Energy, Copenhagen (Denmark)); Engelund Thomsen, K. (Aalborg Univ., SBi, Hoersholm (Denmark))

    2008-09-15

    This report has been developed under the research project 'Etablering af grundlag for energitjenester i Danmark' (project number: ENS-33031-0185) under the Danish research programme - EFP. The objective of this project has been to contribute to the utilisation of the large potential for energy conservations in the building sector within the public, industry and service sectors through the development of a better basis for decision making for both the Energy Service Companies (ESCOes) and the building owners. The EU directive on Energy Service Contracting points at the buildings as the area where the biggest potential market for energy services and energy efficiency improvements are. The EFP-project has two parts: (1) A Danish part and (2) participation in the international cooperation project 'Holistic Assesment Tool-Kit on Energy Efficient Retrofit Measures for Government Buildings (EnERGo)', Annex 46 under the IEA R and D program 'Energy Conservation In Buildings And Community Systems' (ECBCS). This report describes the Danish contributions to the IEA projects subtask B, which has a primary objective to develop a database of energy conservation measures (ECM) with descriptions and performance characteristics of these. (au)

  20. Potential and limitations of multidecadal satellite soil moisture observations for selected climate model evaluation studies

    Directory of Open Access Journals (Sweden)

    A. Loew

    2013-09-01

    Full Text Available Soil moisture is an essential climate variable (ECV of major importance for land–atmosphere interactions and global hydrology. An appropriate representation of soil moisture dynamics in global climate models is therefore important. Recently, a first multidecadal, observation-based soil moisture dataset has become available that provides information on soil moisture dynamics from satellite observations (ECVSM, essential climate variable soil moisture. The present study investigates the potential and limitations of this new dataset for several applications in climate model evaluation. We compare soil moisture data from satellite observations, reanalysis and simulations from a state-of-the-art land surface model and analyze relationships between soil moisture and precipitation anomalies in the different dataset. Other potential applications like model parameter optimization or model initialization are not investigated in the present study. In a detailed regional study, we show that ECVSM is capable to capture well the interannual and intraannual soil moisture and precipitation dynamics in the Sahelian region. Current deficits of the new dataset are critically discussed and summarized at the end of the paper to provide guidance for an appropriate usage of the ECVSM dataset for climate studies.

  1. Production of genetically and developmentally modified seaweeds: Exploiting the potential of artificial selection techniques

    Directory of Open Access Journals (Sweden)

    Bénédicte eCharrier

    2015-03-01

    Full Text Available Plant feedstock with specific, modified developmental features has been a quest for centuries. Since the development and spread of agriculture, there has been a desire for plants producing disproportionate — or more abundant and more nutritional — biomass that meet human needs better than their native counterparts. Seaweed aquaculture, targeted for human consumption and the production of various raw materials, is a rapidly expanding field and its stakeholders have increasing vested interest for cost-effective and lucrative seaweed cultivation processes. Thus, scientific research on seaweed development is particularly timely: the potential for expansion of seaweed cultivation depends on the sector’s capacity to produce seaweeds with modified morphological features (e.g. thicker blades, higher growth rates or delayed (or even no fertility. Here, we review the various technical approaches used to modify development in macroalgae, which have attracted little attention from developmental biologists to date. Because seaweed (or marine macroalgae anatomy is much less complex than that of land plants and because seaweeds belong to three different eukaryotic phyla, the mechanisms controlling their morphogenesis are key to understanding their development. Here, we present efficient sources of developmentally and genetically modified seaweeds — somatic variants, artificial hybrids and mutants — as well as the future potential of these techniques.

  2. Production of genetically and developmentally modified seaweeds: exploiting the potential of artificial selection techniques.

    Science.gov (United States)

    Charrier, Bénédicte; Rolland, Elodie; Gupta, Vishal; Reddy, C R K

    2015-01-01

    Plant feedstock with specific, modified developmental features has been a quest for centuries. Since the development and spread of agriculture, there has been a desire for plants producing disproportionate-or more abundant and more nutritional-biomass that meet human needs better than their native counterparts. Seaweed aquaculture, targeted for human consumption and the production of various raw materials, is a rapidly expanding field and its stakeholders have increasing vested interest for cost-effective and lucrative seaweed cultivation processes. Thus, scientific research on seaweed development is particularly timely: the potential for expansion of seaweed cultivation depends on the sector's capacity to produce seaweeds with modified morphological features (e.g., thicker blades), higher growth rates or delayed (or even no) fertility. Here, we review the various technical approaches used to modify development in macroalgae, which have attracted little attention from developmental biologists to date. Because seaweed (or marine macroalgae) anatomy is much less complex than that of land plants and because seaweeds belong to three different eukaryotic phyla, the mechanisms controlling their morphogenesis are key to understanding their development. Here, we present efficient sources of developmentally and genetically modified seaweeds-somatic variants, artificial hybrids and mutants-as well as the future potential of these techniques.

  3. Microbial antagonism as a potential solution for controlling selected root pathogens of crops

    Science.gov (United States)

    Cooper, Sarah; Agnew, Linda; Pereg, Lily

    2016-04-01

    Root pathogens of crops can cause large reduction in yield, however, there is a limited range of effective methods to control such pathogens. Soilborne pathogens that infect roots often need to survive in the rhizosphere, where there is high competition from other organisms. In such hot spots of microbial activity and growth, supported by root exudates, microbes have evolved antagonistic mechanisms that give them competitive advantages in winning the limited resources. Among these mechanisms is antibiosis, with production of some significant antifungal compounds including, antibiotics, volatile organic compounds, hydrogen cyanide and lytic enzymes. Some of these mechanisms may suppress disease through controlling the growth of root pathogens. In this project we isolated various fungi and bacteria that suppress the growth of cotton pathogens in vitro. The pathogen-suppressive microbes were isolated from cotton production soils that are under different management strategies, with and without the use of organic amendments. The potential of pathogen-suppressing microbes for controlling the black root rot disease, caused by the soilborne pathogen Thielaviopsis basicola, was confirmed using soil assays. We identified isolates with potential use as inoculant for cotton production in Australia. Having isolated a diverse group of antagonistic microbes enhances the probability that some would survive well in the soil and provide an alternative approach to address the problem of root disease affecting agricultural crops.

  4. SOIL CARBON DYNAMICS AND GLOBAL WARMING POTENTIAL OF SELECTED SOIL SERIES AND LANDUSE CATEGORIES

    Directory of Open Access Journals (Sweden)

    Feba Merin Chacko

    2014-03-01

    Full Text Available Land use conversion is usually accompanied by a decline in soil organic carbon. This work is aimed to determine the soil organic carbon affected by the multiple land use in a particular soil series. The study was conducted in Ustic Haplohumults soil series of Kottayam district of Kerala including land uses like Cropland, Wetland, Agricultural land, Homestead and Mixed vegetation land. Change in land use induced significant losses of soil and particulate organic carbon. The maximum SOC content (7.39% was observed in abandoned paddy field which is nearly 89% more than the lowest values of 0.76% recorded from the Homestead soil. Soil carbon sequestration potential of different land uses varies on spatial and temporal basis along with the interplay of environmental externalities. Potential for CO2 production and global warming of various soils was in accordance with C mineralization and this explains the role and capacity of various land use under consideration to store and release carbon. In the present study it was found that the soils of coconut plantation serve as a better system in terms of maximum SOC storage and minimum carbon emission. The present study reveals the significance and importance of specific land use category which is optimal for particular soil series towards soil carbon storage.

  5. Salicylate-selective Potential Response of an Electrode Based on a Copper(Ⅱ)-phthalocyanine Derivative as an Ionophore

    Institute of Scientific and Technical Information of China (English)

    XU Wenju; YUAN Ruo; CHAI Yaqin

    2009-01-01

    Selectivity properties were established for salicylate-selective electrodes prepared by incorporating 2,9,16,23-copper(Ⅱ)-tetranitrophthalocyanine (Cu(Ⅱ)TNPc) and 2,9,16,23-copper(Ⅱ)-tetraaminophthalocyanine (Cu(Ⅱ)TAPc) into plasticized poly(vinyl chloride) (PVC) membranes. The effect of nature of plasticizer, concentrations of iono-phore and anionic and cationic additives on the potential response of the electrode was investigated. The PVC membrane electrode based on Cu(Ⅱ)TNPc exhibited preferential selectivity for salicylate (Sal-) over other tested anions. The best potential response characteristics of a wide working concentration range 1.0×10-1-9.0×10-7 the membrane containing (w/w) 3.0% Cu(II)TNPc, 67.0% o-NPOE, 29.5% PVC, and 0.5% NaTPB. The proposed electrode with good stability and fast response could be used over a pH range of 3.0-7.0. And it was successfully applied to the determination of salicylate in actual samples with satisfactory results.

  6. Identifying Potential Conservation Corridors Along the Mongolia-Russia Border Using Resource Selection Functions: A Case Study on Argali Sheep

    Directory of Open Access Journals (Sweden)

    Buyanaa Chimeddorj

    2013-12-01

    Full Text Available The disruption of animal movements is known to affect wildlife populations, particularly large bodied, free-ranging mammals that require large geographic ranges to survive. Corridors commonly connect fragmented wildlife populations and their habitats, yet identifying corridors rarely uses data on habitat selection and movements of target species. New technologies and analytical tools make it possible to better integrate landscape patterns with spatial behavioral data. We show how resource selection functions can describe habitat suitability using continuous and multivariate metrics to determine potential wildlife movement corridors. During 2005–2010, we studied movements of argali sheep ( Ovis ammon near the Mongolia-Russia border using radio-telemetry and modeled their spatial distribution in relation to landscape features to create a spatially explicit habitat suitability surface to identify potential transboundary conservation corridors. Argali sheep habitat selection in western Mongolia positively correlated with elevation, ruggedness index, and distance to border. In other words, argali were tended use areas with higher elevation, rugged topography, and distances farther from the international border. We suggest that these spatial modeling approaches offer ways to design and identify wildlife corridors more objectively and holistically, and can be applied to many other target species.

  7. Antibacterial potential of selected red seaweeds from Manapad coastal areas, Thoothukudi, Tamil Nadu, India

    Institute of Scientific and Technical Information of China (English)

    Adaikalaraj G; Patric Raja D; Johnson M; Janakiraman N; Babu A

    2012-01-01

    Objective: To evaluate the antibacterial activity of Gracilaria verrucosa (G. verrucosa) (Hudson),Hypnea musciformis falk, Gracilaria ferugosoni (G. ferugosoni), Gelidium species and G. verrucosa var. against the selected bacterial pathogens. Methods: The antibacterial activities of methanol and aqueous hot extracts were tested against various organisms by using disc diffusion method. Results:The highest antibacterial activity (13 mm) was shown by the aqueous extract of G. verrucosa var. against Pseudomonas aeruginosa (P. aeruginosa) and the lowest activity (6 mm) was observed in the methanol extract of E. prolifera against Escherichia coli (E. coli). However in most of the seaweeds, methanol extract was found to be more effective. The microbial strains Salmonella typhi (S. typhi), Staphylococcus aureus (S. aureus), Bacillus subtilis (B. subtilis) and Candida albicans(C. albicans) were resistant to the aqueous extracts of all seaweeds. Conclusion: Further (H. musciformis) (Wulf) Lamour, Enatiocladia prolifera (E. prolifera) (Grev.) work is needed to identify the principle compound which is responsible for antibacterial activity against pathogenic bacteria especially those causing the human diseases.

  8. Mexican rice borer (Lepidoptera: Crambidae) oviposition site selection stimuli on sugarcane, and potential field applications.

    Science.gov (United States)

    Showler, Allan T; Castro, Boris A

    2010-08-01

    The Mexican rice borer, Eoreuma loftini (Dyar) (Lepidoptera: Crambidae), a key pest of sugarcane (Saccharum spp.) and rice, Oryza sativa L., in Texas, has not been controlled with chemical insecticides or biological agents, but some sugarcane varieties have shown degrees of resistance. Assessment of selected sugarcane leaf characteristics indicate that preference for oviposition sites is mostly determined by the presence of a leaf fold and secondarily by the availability of dry leaf tissue, both of which are antixenotic nonchemical stimuli. We suggest that breeding sugarcane lines bearing leaves that do not fold on drying could provide substantial antixenotic resistance against the Mexican rice borer. Previously identified antixenotic chemical stimuli, i.e., low quantities or absence of important nutrients in green leaf tissue, only become apparent when resistant and susceptible sugarcane varieties are compared. Varietal differences in oviposition preference, however, were not observed on excised dry leaf tissue, indicating that expression of resistance in terms of chemical stimuli requires detection of biochemicals in nearby living leaf tissue. Excised dry sugarcane leaves retain the two dominant nonchemical oviposition preference stimuli for Mexican rice borers, and the leaves effectively trapped eggs away from intact plants when dry leaves were used as "mulch" at the bottom of greenhouse cages. Under commercial sugarcane field conditions, bundled dry leaves also collected Mexican rice borer eggs. Possible applications of dry sugarcane leaf substrate for egg scouting and for trapping eggs are discussed.

  9. Virulence potential of Enterococcus gallinarum strains isolated from selected Nigerian traditional fermented foods

    Directory of Open Access Journals (Sweden)

    IYABO C. OLADIPO

    2014-08-01

    Full Text Available Five Enterococcus isolates from some Nigerian traditional fermented foods were identified as Enterococcus gallinarum by using phenotypic and genotypic tests. Safety properties such as antibiotic susceptibility, virulence gene detection, haemolysin, gelatinase and bacteriocin production were determined using standard methods. There was no resistance to clinically relevant antibiotics. Virulence gene for collagen binding antigen and aggregation substance were detected in 60% of the E. gallinarum strains; while surface adhesin was detected in 20%, but none of the strains had cytolysin activator and gelatinase. Phenotype characterizations of the E. gallinarum isolates indicated that none of the isolates produced haemolysin and gelatinase. Enterococcus gallinarum C103 and U82 had no antimicrobial activity against all the selected bacteria pathogens while E. gallinarum W184, T71 and W21 were active against some of the indicator bacteria pathogens. Only E. gallinarum T71 and W21 showed broad spectra of antimicrobial activity. Combination of virulence factors did not appear in these food isolates. Therefore, these strains particularly the two strains with high spectra of antimicrobial activity could be exploited as functional starters in foods.

  10. Keynote address: cellular reduction of nitroimidazole drugs: potential for selective chemotherapy and diagnosis of hypoxic cells

    Energy Technology Data Exchange (ETDEWEB)

    Chapman, J.D.; Lee, J.; Meeker, B.E.

    1989-04-01

    Nitroimidazole drugs were initially developed as selective radiosensitizers of hypoxic cells and, consequently, as adjuvants to improve the local control probabilities of current radiotherapies. Misonidazole (MISO), the prototype radiosensitizing drug, was found in Phase I clinical studies to cause dose-limiting neurotoxicities (mainly peripheral neuropathies). MISO was also found to be cytotoxic in the absence of radiation and to covalently bind to cellular molecules, both processes demonstrating rates much higher in hypoxic compared with oxygenated cells. It is likely that neurotoxicity, cellular cytotoxicity and adduct formation results from reactions between reduction intermediates of MISO and cellular target molecules. Spin-offs from radiosensitizer research include the synthesis and characterization of more potent hypoxic cytotoxins and the exploitation of sensitizer-adducts as probes for measuring cellular and tissue oxygen levels. Current developments in hypoxic cell cytotoxin and hypoxic cell marker research are reviewed with specific examples from studies which characterize the cellular reduction of TF-MISO, (1-(2-nitro-1-imidazolyl)-3(2,2,2-trifluoroethoxy)-2-propanol). 45 references.

  11. Phytoremediation potential of Alocasia microrrhiza grown on soil collected from selected dumpsites in Ekiti State, Nigeria

    Directory of Open Access Journals (Sweden)

    Asaolu S. S.

    2013-04-01

    Full Text Available This study investigates the effect of enhanced phytoextraction on the accumulation of heavy metals by Alocasia microrrhiza cultivated on soil collected from selected dumpsites in Ekiti State, Nigeria. The application of 1g/kg EDTA decreased the heights of plants relative to control, but significantly increased the concentration of heavy metals in various tissues of the plant. Notably, concentration of Pb and Cu were greater than the threshold value of 100mg/kg, indicative of the fact that Alocasia microrrhiza could be a good candidate for Pb and Cuphytoextraction. BF, TF and RR values (1.1–1.6, (4.3-4.8 and (1.4–2.3 revealed the effectiveness of the plant to translocate Pb and Cu to their harvestable portion. RRs values greater than one also indicated the efficiency of plant under chelate-induced phytoextraction. However, the concentration of heavy metals did not vary significantly at p < 0.05 (LSD test in all dumpsites investigated.

  12. A novel caspase 8 selective small molecule potentiates TRAIL-induced cell death.

    Science.gov (United States)

    Bucur, Octavian; Gaidos, Gabriel; Yatawara, Achani; Pennarun, Bodvael; Rupasinghe, Chamila; Roux, Jérémie; Andrei, Stefan; Guo, Bingqian; Panaitiu, Alexandra; Pellegrini, Maria; Mierke, Dale F; Khosravi-Far, Roya

    2015-05-11

    Recombinant soluble TRAIL and agonistic antibodies against TRAIL receptors (DR4 and DR5) are currently being created for clinical cancer therapy, due to their selective killing of cancer cells and high safety characteristics. However, resistance to TRAIL and other targeted therapies is an important issue facing current cancer research field. An attractive strategy to sensitize resistant malignancies to TRAIL-induced cell death is the design of small molecules that target and promote caspase 8 activation. For the first time, we describe the discovery and characterization of a small molecule that directly binds caspase 8 and enhances its activation when combined with TRAIL, but not alone. The molecule was identified through an in silico chemical screen for compounds with affinity for the caspase 8 homodimer's interface. The compound was experimentally validated to directly bind caspase 8, and to promote caspase 8 activation and cell death in single living cells or population of cells, upon TRAIL stimulation. Our approach is a proof-of-concept strategy leading to the discovery of a novel small molecule that not only stimulates TRAIL-induced apoptosis in cancer cells, but may also provide insights into the structure-function relationship of caspase 8 homodimers as putative targets in cancer.

  13. Serologic survey for selected arboviruses and other potential pathogens in wildlife from Mexico.

    Science.gov (United States)

    Aguirre, A A; McLean, R G; Cook, R S; Quan, T J

    1992-07-01

    During 1988 and 1989, a serologic survey of wildlife was conducted in northeastern Mexico to determine the presence, prevalence, and distribution of arboviruses and other selected disease agents. Eighty mammal specimens were tested. Antibodies to vesicular stomatitis-Indiana, Venezuelan equine encephalitis-Mena II, Rio Grande virus, and vesicular stomatitis-New Jersey were detected predominantly in small mammals. Deer and mouflon (Ovis musimon) had antibodies to bluetongue and epizootic hemorrhagic disease. Two species had serologic evidence of recent exposure to Francisella tularensis. A white-tailed deer (Odocoileus virginianus) had antibodies to Anaplasma marginale. All specimens tested for antibodies against Yersinia pestis and Brucella abortus were negative. Sera from 315 birds were tested for antibody against five equine encephalitis viruses and six avian pathogens. During 1988, antibodies to Venezuelan equine encephalitis-Mena II, Venezuelan equine encephalitis-TC83, St. Louis encephalitis, eastern equine encephalitis, and western equine encephalitis were detected in birds of several species. Antibodies to Pasteurella multocida and Newcastle disease virus were also detected. Birds from five species presented antibodies to Mycoplasma meleagridis. Specimens tested for M. gallisepticum, M. synoviae, and Chlamydia psittaci were negative. To the best of our knowledge, this survey represents the first serologic evidence of bluetongue, Cache Valley virus, epizootic hemorrhagic disease, Jamestown Canyon virus, vesicular stomatitis-Indiana, vesicular stomatitis-New Jersey, Rio Grande virus, and tularemia reported among wildlife in Mexico.

  14. Selectivity and potential interference from phenolic compounds in chemiluminescence methods for the determination of synephrine.

    Science.gov (United States)

    Francis, Paul S; Brown, Allyson J; Bellomarino, Sara A; Taylor, Amelia M; Slezak, Teo; Barnett, Neil W

    2009-01-01

    Three recently reported chemiluminescence methods (based on reactions with alkaline luminol and hexacyanoferrate(III); acidic cerium(IV) and rhodamine B; and acidic permanganate with polyphosphates) for the determination of synephrine were re-evaluated in terms of their selectivity towards this analyte in comparison to other phenolic compounds. A fourth reagent system, acidic soluble manganese(IV) and formaldehyde, was also examined. Each set of reagents was sensitive towards synephrine (limits of detection were 3 x 10(-9), 5 x 10(-8), 1 x 10(-8) and 1 x 10(-8) mol/L, respectively) but also responded with numerous other phenolic compounds, including some that are present in citrus fruit extracts, dietary supplements and/or biological fluids. It is therefore recommended that the determination of synephrine in these matrices should incorporate physical separation of sample components (e.g. chromatography or electrophoresis). In more general terms, this study illustrates that accurate percentage recoveries for an analyte in spiked samples (without validation against another analytical method) are insufficient to confirm the analytical utility of new flow-injection analysis (FIA) procedures.

  15. Investigation of therapeutic potentials of some selected medicinal plants using neutron activation analysis

    Energy Technology Data Exchange (ETDEWEB)

    Abubakar, Sani; Isa, Nasiru Fage [Bayero University, Kano Nigeria (Nigeria); Usman, Ahmed Rufa’i [University of Malaya, Kuala Lumpur (Malaysia); Umaru Musa Yar’adua University, Katsina Nigeria (Nigeria); Khandaker, Mayeen Uddin [University of Malaya, Kuala Lumpur (Malaysia); Abubakar, Nuraddeen [Center for Energy Research and Training, Ahmadu Bello University, Zaria Nigeria (Nigeria)

    2015-04-24

    Series of attempts were made to investigate concentrations of trace elements and their therapeutic properties in various medicinal plants. In this study, samples of some commonly used plants were collected from Bauchi State, Nigeria. They includes leaves of azadirachta indica (neem), Moringa Oleifera (moringa), jatropha curcas (purgin Nut), guiera senegalensis (custard apple) and anogeissus leiocarpus (African birch). These samples were analyzed for their trace elements contents with both short and long irradiation protocols of Instrumental Neutron Activation Analysis (INAA) at Nigerian Research Reactor-1 (NIRR-1) of Ahmadu Bello University, Zaria, Nigeria. The level of trace elements found varies from one sample to another, with some reported at hundreds of mg/Kg dry weight. The results have been compared with the available literature data. The presence of these trace elements indicates promising potentials of these plants for relief of certain ailments.

  16. Investigation of therapeutic potentials of some selected medicinal plants using neutron activation analysis

    Science.gov (United States)

    Abubakar, Sani; Usman, Ahmed Rufa'i.; Isa, Nasiru Fage; Khandaker, Mayeen Uddin; Abubakar, Nuraddeen

    2015-04-01

    Series of attempts were made to investigate concentrations of trace elements and their therapeutic properties in various medicinal plants. In this study, samples of some commonly used plants were collected from Bauchi State, Nigeria. They includes leaves of azadirachta indica (neem), Moringa Oleifera (moringa), jatropha curcas (purgin Nut), guiera senegalensis (custard apple) and anogeissus leiocarpus (African birch). These samples were analyzed for their trace elements contents with both short and long irradiation protocols of Instrumental Neutron Activation Analysis (INAA) at Nigerian Research Reactor-1 (NIRR-1) of Ahmadu Bello University, Zaria, Nigeria. The level of trace elements found varies from one sample to another, with some reported at hundreds of mg/Kg dry weight. The results have been compared with the available literature data. The presence of these trace elements indicates promising potentials of these plants for relief of certain ailments.

  17. Potential for bioremediation of agro-industrial effluents with high loads of pesticides by selected fungi.

    Science.gov (United States)

    Karas, Panagiotis A; Perruchon, Chiara; Exarhou, Katerina; Ehaliotis, Constantinos; Karpouzas, Dimitrios G

    2011-02-01

    Wastewaters from the fruit packaging industry contain a high pesticide load and require treatment before their environmental discharge. We provide first evidence for the potential bioremediation of these wastewaters. Three white rot fungi (WRF) (Phanerochaete chrysosporium, Trametes versicolor, Pleurotus ostreatus) and an Aspergillus niger strain were tested in straw extract medium (StEM) and soil extract medium (SEM) for degrading the pesticides thiabendazole (TBZ), imazalil (IMZ), thiophanate methyl (TM), ortho-phenylphenol (OPP), diphenylamine (DPA) and chlorpyrifos (CHL). Peroxidase (LiP, MnP) and laccase (Lac) activity was also determined to investigate their involvement in pesticide degradation. T. versicolor and P. ostreatus were the most efficient degraders and degraded all pesticides (10 mg l⁻¹) except TBZ, with maximum efficiency in StEM. The phenolic pesticides OPP and DPA were rapidly degraded by these two fungi with a concurrent increase in MnP and Lac activity. In contrast, these enzymes were not associated with the degradation of CHL, IMZ and TM implying the involvement of other enzymes. T. versicolor degraded spillage-level pesticide concentrations (50 mg l⁻¹) either fully (DPA, OPP) or partially (TBZ, IMZ). The fungus was also able to rapidly degrade a mixture of TM/DPA (50 mg l⁻¹), whereas it failed to degrade IMZ and TBZ when supplied in a mixture with OPP. Overall, T. versicolor and P. ostreatus showed great potential for the bioremediation of wastewaters from the fruit packaging industry. However, degradation of TBZ should be also achieved before further scaling up.

  18. New species of Amanita from the eastern Himalaya and adjacent regions.

    Science.gov (United States)

    Yang, Zhu L; Weiß, M; Oberwinkler, F

    2004-01-01

    Four new species of Amanita, Amanita-ceae (Agaricales) are described from the eastern Himalaya and adjacent regions of southwestern China. Amanita altipes and A. parvipantherina are members of section Amanita, while A. orientifulva and A. liquii are representatives of section Vaginatae. They are compared with similar species and illustrated with line drawings.

  19. Use of Indigenous Knowledge in Environmental Decision-Making by Communities in the Kumaon Himalayas

    Science.gov (United States)

    Honwad, Sameer

    2010-01-01

    This study is designed to find out how people in rural communities residing in the middle Himalayas use indigenous knowledge to support environmental decisions while addressing water and land use related concerns. The study not only serves to enrich our understanding of community decision-making, especially as connected to land use and ecological…

  20. Petrography, geochemistry and regional significance of crystalline klippen in the Garhwal Lesser Himalaya, India

    Indian Academy of Sciences (India)

    R Islam; S K Ghosh; S Vyshnavi; Y P Sundriya

    2011-06-01

    Uphalda gneisses (UG) is a crystalline klippe located near Srinagar in Garhwal Himalaya. These gneisses are compared with Debguru porphyroids (DP) (≈ Ramgarh group) of Garhwal–Kumaun Himalaya and Baragaon mylonitic gneisses (BMG) of Himachal Himalaya. Petrographic study reveals that the deformation of UG was initiated at higher temperature (above 350°C) and continued till lowering of temperature and deformation led to the mylonitization. Geochemically, these granitic gneisses (UG, DP and BMG) exhibit similar composition. Features such as high molecular A/CNK value (< 1), presence of normative corundum and absence of normative diopside, enhanced Rb/Sr, Rb/Zr ratios, enrichment of Th and containing rounded zircons support their crustally-derived S-type granitic nature. The linear plot in major oxides is interpreted in terms of fractional crystallization processes. Mantle normalized multi-element spider diagram of UG illustrates depletion of Ba, Nb, Sr, P and Ti and enrichment of Th and show similarities with DP and BMG. Similarities were observed in lithology, petrographic characters and chemical composition of UG, DP, BMG and Ulleri augen gneisses (Nepal). Comparison with the rocks of Higher Himalayan crystallines (≈ Vaikrita), suggests that these rocks (UG) are not transported from Higher Himalaya as understood earlier. This study however proposes that, these gneissic bodies represent an older basement occurring as a tectonic sliver which emplaced within the cover sequence as wedges at different structural levels. This is a regional phenomena observed throughout the Lesser Himalayan region.

  1. Contribution of pack animals in reducing CO{sub 2} emission in Central Himalaya, India

    Energy Technology Data Exchange (ETDEWEB)

    Farooquee, N.A.; Budal, T.K.; Maikhuri, R.K. [G.B. Pant Institute of Himalayan Environment and Development, Srinagar (India); Singh, S.P. [H.N.B. Garhwal Univ., Srinagar (India)

    2008-07-10

    The resilience and adaptation in mountain regions have acquired important priorities in the present time, especially when climatic change has become an overriding issue and its impacts are recognized to be felt globally. The present study describes an example of how the pack animals play a vital role in transportation in remote and far-flung areas of Uttarakhand Himalaya, and also contribute in reducing CO{sub 2} emission. This article attempts to estimate the changes in the rate of CO{sub 2} emission if the present transportation of goods by pack animals is carried out by automobiles, i.e. the contribution of equines to carbon saving in the Himalaya while rendering transportation services. It also suggests an option for reducing CO{sub 2} emission by utilizing pack animals in the transportation of non essential commodities in remote and rural areas. The present study was undertaken in the six major valleys of Garhwal Himalaya, Uttarakhand to understand and quantify the contribution of pack animals in reducing CO{sub 2} emission in Indian Central Himalaya. The study has demonstrated that horses and mules provide direct and indirect services to the society and country. The direct services include communication services in far-flung and remote areas not connected with the road network, where they transport essential commodities and also human beings to the religious shrines of Kedarnath, Hem Kund, Gangotri and Yamunotri. The indirect services include reduction in CO{sub 2} emission.

  2. Phenotypic variation in the Snowtrout Schizothorax richardsonii (Gray, 1832) (Actinopterygii: Cypriniformes: Cyprinidae) from the Indian Himalayas

    NARCIS (Netherlands)

    Mir, F.A.; Mir, J.I.; Chandra, S.

    2013-01-01

    We investigated intraspecific variation of the Snowtrout, Schizothorax richardsonii on the basis of morphometric characters. Altogether, 217 specimens were collected from four rivers in the Western and Central Indian Himalaya. A truss network was constructed by interconnecting 14 landmarks to yield

  3. High-resolution modeling of atmospheric dynamics in the Nepalese Himalaya

    NARCIS (Netherlands)

    Collier, Emily; Immerzeel, Walter W.

    2015-01-01

    High-altitude meteorological processes in the Himalaya are influenced by complex interactions between the topography and the monsoon and westerly circulation systems. In this study, we use the Weather Research and Forecasting model configured with high spatial resolution to understand seasonal patte

  4. Climate-driven sediment aggradation and incision since the late Pleistocene in the NW Himalaya, India

    Science.gov (United States)

    Dey, Saptarshi; Thiede, Rasmus C.; Schildgen, Taylor F.; Wittmann, Hella; Bookhagen, Bodo; Scherler, Dirk; Jain, Vikrant; Strecker, Manfred R.

    2016-09-01

    Deciphering the response of sediment routing systems to climatic forcing is fundamental for understanding the impacts of climate change on landscape evolution. In the Kangra Basin (northwest Sub-Himalaya, India), upper Pleistocene to Holocene alluvial fills and fluvial terraces record periodic fluctuations of sediment supply and transport capacity on timescales of 103 to 105 yr. To evaluate the potential influence of climate change on these fluctuations, we compare the timing of aggradation and incision phases recorded within remnant alluvial fans and terraces with climate archives. New surface-exposure dating of six terrace levels with in-situ cosmogenic 10Be indicates the onset of incision phases. Two terrace surfaces from the highest level (T1) sculpted into the oldest preserved alluvial fan (AF1) date back to 53.4 ± 3.2 ka and 43.0 ± 2.7 ka (1σ). T2 surfaces sculpted into the remnants of AF1 have exposure ages of 18.6 ± 1.2 ka and 15.3 ± 0.9 ka, while terraces sculpted into the upper Pleistocene-Holocene fan (AF2) provide ages of 9.3 ± 0.4 ka (T3), 7.1 ± 0.4 ka (T4), 5.2 ± 0.4 ka (T5) and 3.6 ± 0.2 ka (T6). Together with previously published OSL ages yielding the timing of aggradation, we find a correlation between variations in sediment transport with oxygen-isotope records from regions affected by the Indian Summer Monsoon. During periods of increased monsoon intensity and post-Last Glacial Maximum glacial retreat, aggradation occurred in the Kangra Basin, likely due to high sediment flux, whereas periods of weakened monsoon intensity or lower sediment supply coincide with incision.

  5. Volatile organic compounds over Eastern Himalaya, India: temporal variation and source characterization using Positive Matrix Factorization

    Directory of Open Access Journals (Sweden)

    C. Sarkar

    2014-12-01

    Full Text Available A first ever study on the characterization of volatile organic compounds (VOCs has been made over a Himalayan high altitude station in India. A total of 18 VOCs (mono aromatics-BTEX (benzene, toluene, ethylbenzene, xylene, non-BTEX substituted aromatics and halocarbon have been measured over Darjeeling (27.01° N, 88.15° E, 2200 m a.s.l. in the eastern Himalaya in India during the period of July 2011–June 2012. The annual average concentration of the sum of 18 target VOCs (TVOC was 376.3 ± 857.2 μg m−3. Monoaromatics had the highest contribution (72% followed by other substituted aromatics (22% and halocarbon (6% compounds. Toluene was the most abundant VOC in the atmosphere of Darjeeling with the contribution of ~37% to TVOC followed by benzene (~21%, ethylbenzene (~9% and xylenes (~6%. TVOC concentrations were highest during the postmonsoon season with minimum solar radiation and lowest during the premonsoon season with maximum solar radiation. Anthropogenic activities related mainly to tourists like diesel and gasoline emissions, biomass and coal burning, use of solvent and solid waste emissions were almost equal in both the seasons. Seasonal variation in TVOCs over Darjeeling was mainly governed by the incoming solar radiation rather than the emission sources. Source apportionment study using Positive Matrix Factorization (PMF model indicated that major fraction of (~60% TVOC were contributed by diesel and gasoline exhausts followed by solvent evaporation (18% and other sources. Diesel exhaust was also found to have the maximum potential in tropospheric ozone formation. The atmospheric loading of BTEX over Darjeeling was found to be comparable with several Indian metro cities and much higher than other cities around the world.

  6. Evaluation of antifungal potential of selected medicinal plants against human pathogenic fungi

    Directory of Open Access Journals (Sweden)

    Hayat Sakander

    2015-01-01

    Full Text Available Context: Evaluation of medicinal plants used in traditional medicine lead to novel bioactive compounds with antifungal activity that could be exploited as therapeutic agents. Aims: The aim was to screen selected medicinal plants for antifungal activity against three important human pathogenic fungi and to identify the broad group of phytochemicals responsible for the activity. Materials and Methods: A total of 8 medicinal plants were screened for antifungal activity against three human pathogenic fungi. Aqueous and the solvent extracts of the plant materials were prepared by polarity based solvent extraction. Antifungal activity was tested by well and disc diffusion methods. Minimum inhibitory concentration (MIC of the active extract was determined by micro-broth dilution technique. Phytochemical analysis of the active extract was done. Statistical Analysis Used: The results were statistically analysed by One-Way analysis of variance with Post-hoc Tukey′s B test at P < 0.05 using the  Software SPSS version 20 (IBM Corp. Armonk, NY Released 2011. Results: Significant antifungal activity was observed in the aqueous extracts of the fruits of Terminalia chebula (47.75 mm against Microsporum gypseum and the mesocarp of Persea americana (40.5 mm against Microsporum canis. Candida albicans was inhibited by the ethyl acetate (20 mm and aqueous extracts (16 mm of T. chebula fruits and aqueous extract of the seeds of Syzygium jambos (16 mm. The aqueous extract of mesocarp of P. americana showed lowest MIC value (312.5 μg/ml against M. canis and M. gypseum. Phytochemical analysis of the active extracts revealed the presence of phenols, tannins, alkaloids and flavonoids. Conclusions: The study validates the use of the plants in the treatment of fungal infections and has provided important leads for the discovery of new plant-based antifungal agents.

  7. Helpful or harmful? Potential effects of exercise on select inflammatory conditions.

    Science.gov (United States)

    Thomas, Jennifer L

    2013-11-01

    Inflammation has been characterized as a double-edged sword, requiring a balance between health as maintained by regular exercise and activities that would exacerbate inflammatory diseases. The influence of exercise on inflammation is complex and has been widely studied in both healthy patient populations as well as populations of patients with many inflammatory and/or autoimmune rheumatic diseases. Inflammatory markers can be affected by the type of exercise and muscle contraction, as well as the intensity, duration, and consistency of the exercise sessions. Because of these potentially important effects, many members of the general public, as well as some clinicians, believe that exercise could exacerbate symptoms and accelerate the progression of such conditions. The effects of different types of exercise have been studied among patients with inflammatory conditions such as ankylosing spondylitis, systemic lupus erythematosus, rheumatoid arthritis, osteoarthritis, fibromyalgia, and idiopathic inflammatory myopathies, as well as congestive heart failure, type 2 diabetes mellitus, and metabolic syndrome, which are considered low-grade systemic inflammatory diseases. This review will help exercise professionals and clinicians understand the effects of exercise on inflammatory markers, as well as offer effective treatment options and recommendations for patients exercising with rheumatic or inflammatory conditions.

  8. Selection of potential cold water marine species for testing of oil dispersants, and chemically dispersed oil

    Energy Technology Data Exchange (ETDEWEB)

    Perkins, R.A. [Alaska Univ., Fairbanks, AK (United States). Dept. of Civil and Environmental Engineering

    2000-07-01

    A study regarding marine species for toxicity testing for Alaska conditions was presented and the potential adverse impacts of a large marine oil spill in cold water were discussed with the objective to determine if the spill should be treated by the use of oil dispersants. Without dispersion, the oil can pollute marine epifauna and can deposit on beaches. The decision to apply dispersants to a marine oil spill requires knowledge of the toxicity of the undispersed oil to pelagic marine life occurring via natural dispersion as opposed to the toxicity of the oil-dispersant mixture. Most standard toxicity tests apply to warm water species. This paper discussed the need to have a standard test species relevant to Alaska waters for toxicity testing. In this study, toxicity testing was done according to the methods of the Chemical Response to Oil Spills : Ecological Effects Research Forum (CROSERF). The testing included capturing adult species in the winter and holding them until larval hatching. Toxicity testing was completed in a narrow time frame before hatching ceased. Many chemical samples were tested. Topsmelt, urchins, shellfish, mysids, copepods, pink salmon fry, and tidepool sculpin were considered by the author to be the most useful for certain types of toxicity testing. 29 refs.

  9. Quinolinic acid selectively induces apoptosis of human astrocytes: potential role in AIDS dementia complex

    Directory of Open Access Journals (Sweden)

    Wang Lily

    2005-07-01

    Full Text Available Abstract There is evidence that the kynurenine pathway (KP and particularly one of its end products, quinolinic acid (QUIN play a role in the pathogenesis of several major neuroinflammatory diseases, and more particularly AIDS dementia complex (ADC. We hypothesized that QUIN may be involved in astrocyte apoptosis because: 1 apoptotic astrocytes have been observed in the brains of ADC patients, 2 ADC patients have elevated cerebrospinal fluid QUIN concentrations, and 3 QUIN can induce astrocyte death. Primary cultures of human fetal astrocytes were treated with three pathophysiological concentrations of QUIN. Numeration of apoptotic cells was assessed using double immunocytochemistry for expression of active caspase 3 and for nucleus condensation. We found that treatment of human astrocytes with QUIN induced morphological (cell body shrinking and biochemical changes (nucleus condensation and over-expression of active caspase 3 of apoptosis. After 24 hours of treatment with QUIN 500 nM and 1200 nM respectively 10 and 14% of astrocytes were undergoing apoptosis. This would be expected to lead to a relative lack of trophic support factors with consequent neuronal dysfunction and possibly death. Astroglial apoptosis induced by QUIN provides another potential mechanism for the neurotoxicity of QUIN during ADC.

  10. Potential consequences of selection to change gestation length on performance of Holstein cows.

    Science.gov (United States)

    Norman, H D; Wright, J R; Miller, R H

    2011-02-01

    Genetic evaluations for gestation length (GL) for Holstein service sires were studied to determine their effectiveness in predicting GL in an independent data set. Consequences of selection on GL were also assessed by examining correlated changes in milk and fitness traits. Holstein bulls with ≥ 300 calvings between 1998 and 2005 were stratified into the following 7 groups using predicted transmitting ability (PTA) for service sire GL: <-3.00, -3.00 to -2.01, …, 1.00 to 1.99, and ≥ 2.00 d. An independent set of 261,598 first-parity cows mated later to the same bulls and calving between 2006 and 2009 were segregated by the service sire PTA GL groups (group had 8,317 to 73,324 gestations), and these mates' GL were examined to determine effectiveness of service sire PTA GL. The model included fixed effects for herd-year and service sire group, plus covariates for conception dates to account for time opportunity among mates. Mean GL for mates by service sire group (from lowest to highest PTA GL) were 275.3, 276.5, 277.8, 278.6, 279.5, 280.6, and 281.7 d. Thus, service sire PTA GL was effective in identifying bulls that modified GL. Subsequent yield and fitness traits were also examined for the (independent) mates with the same service sire groups. Intermediate service sire PTA GL was optimal for yield traits and days open; performance for productive life and culling generally became less favorable as service sire PTA GL increased. A second examination was made by replacing service sire PTA GL groups in the model with phenotypic cow GL groups. Relationships between GL and subsequent performance for milk yield and fitness traits were examined using 9 phenotypic cow GL groups: ≤ 271, 272-273, …, 284-285, and ≥ 286 d. Performance generally improved for subsequent lactation yield as cow GL increased; however, intermediate GL was optimal for productive life, calving ease, stillbirth, culling, and days open. Results indicated that neither shortening nor increasing

  11. Mountain range specific analog weather forecast model for northwest Himalaya in India

    Indian Academy of Sciences (India)

    D Singh; A Ganju

    2008-10-01

    Mountain range specific analog weather forecast model is developed utilizing surface weather observations of reference stations in each mountain range in northwest Himalaya (NW-Himalaya).The model searches past similar cases from historical dataset of reference observatory in each mountain range based on current situation.The searched past similar cases of each mountain range are used to draw weather forecast for that mountain range in operational weather forecasting mode, three days in advance.The developed analog weather forecast model is tested with the independent dataset of more than 717 days (542 days for Pir Panjal range in HP)of the past 4 winters (2003 –2004 to 2006 –2007).Independent test results are reasonably good and suggest that there is some possibility of forecasting weather in operational weather forecasting mode employing analog method over different mountain ranges in NW-Himalaya.Significant difference in overall accuracy of the model is found for prediction of snow day and no-snow day over different mountain ranges, when weather is predicted under snow day and no-snow day weather forecast categories respectively.In the same mountain range,signi ficant difference is also found in overall accuracy of the model for prediction of snow day and no-snow day for different areas.This can be attributed to their geographical position and topographical differences.The analog weather forecast model performs better than persistence and climatological forecast for day-1 predictions for all the mountain ranges except Karakoram range in NW-Himalaya.The developed analog weather forecast model may help as a guidance tool for forecasting weather in operational weather forecasting mode in different mountain ranges in NW-Himalaya.

  12. Review: Assessing potential dietary toxicity of heavy metals in selected vegetables and food crops

    Institute of Scientific and Technical Information of China (English)

    ISLAM Ejaz ul; YANG Xiao-e; HE Zhen-li; MAHMOOD Qaisar

    2007-01-01

    Heavy metals, such as cadmium, copper, lead, chromium and mercury, are important environmental pollutants,particularly in areas with high anthropogenic pressure. Their presence in the atmosphere, soil and water, even in traces can cause serious problems to all organisms, and heavy metal bioaccumulation in the food chain especially can be highly dangerous to human health. Heavy metals enter the human body mainly through two routes namely: inhalation and ingestion, ingestion being the main route of exposure to these elements in human population. Heavy metals intake by human populations through food chain has been reported in many countries. Soil threshold for heavy metal toxicity is an important factor affecting soil environmental capacity of heavy metal and determines heavy metal cumulative loading limits. For soil-plant system, heavy metal toxicity threshold is the highest permissible content in the soil (total or bioavailable concentration) that does not pose any phytotoxic effects or heavy metals in the edible parts of the crops does not exceed food hygiene standards. Factors affecting the thresholds of dietary toxicity of heavy metal in soil-crop system include: soil type which includes soil pH, organic matter content, clay mineral and other soil chemical and biochemical properties; and crop species or cultivars regulated by genetic basis for heavy metal transport and accumulation in plants. In addition, the interactions of soil-plant root-microbes play important roles in regulating heavy metal movement from soil to the edible parts of crops. Agronomic practices such as fertilizer and water managements as well as crop rotation system can affect bioavailability and crop accumulation of heavy metals, thus influencing the thresholds for assessing dietary toxicity of heavy metals in the food chain. This paper reviews the phytotoxic effects and bioaccumulation of heavy metals in vegetables and food crops and assesses soil heavy metal thresholds for potential dietary

  13. Development of live attenuated Streptococcus agalactiae as potential vaccines by selecting for resistance to sparfloxacin.

    Science.gov (United States)

    Pridgeon, Julia W; Klesius, Phillip H

    2013-05-31

    To develop attenuated bacteria as potential live vaccines, sparfloxacin was used in this study to modify 40 isolates of Streptococcus agalactiae. Majority of S. agalactiae used in this study were able to develop at least 80-fold resistance to sparfloxacin. When the virulence of the sparfloxacin-resistant S. agalactiae isolates were tested in 10-12g Nile tilapia by intraperitoneal injection at dose of 2×10(7)CFU/fish, 31 were found to be avirulent to fish. Of the 31 avirulent sparfloxacin-resistant S. agalactiae isolates, 30 provided 75-100% protection to 10-12g Nile tilapia against challenges with a virulent S. agalactiae isolate Sag 50. When the virulence of the 30 sparfloxacin-resistant S. agalactiae isolates was tested in 3-5g Nile tilapia by intraperitoneal injection at dose of 2×10(7)CFU/fish, six were found to be avirulent to 3-5g Nile tilapia. Of the six avirulent sparfloxacin-resistant S. agalactiae isolates, four provided 3-5g Nile tilapia 100% protection against challenges with homologous isolates, including Sag 97-spar isolate that was non-hemolytic. However, Sag 97-spar failed to provide broad cross-protection against challenges with heterologous isolates. When Nile tilapia was vaccinated with a polyvalent vaccine consisting of 30 sparfloxacin-resistant S. agalactiae isolates at dose of 2×10(6)CFU/fish, the polyvalent vaccine provided significant (P<0.001) protection to both 3-5g and 15-20g Nile tilapia against challenges with 30 parent isolates of S. agalactiae. Taken together, our results suggest that a polyvalent vaccine consisting of various strains of S. agalactiae might be essential to provide broader protection to Nile tilapia against infections caused by S. agalactiae.

  14. Wet air oxidation as a pretreatment option for selective biodegradability enhancement and biogas generation potential from complex effluent.

    Science.gov (United States)

    Padoley, K V; Tembhekar, P D; Saratchandra, T; Pandit, A B; Pandey, R A; Mudliar, S N

    2012-09-01

    This study looks at the possibility of wet air oxidation (WAO) based pretreatment of complex effluent to selectively enhance the biodegradability (without substantial COD destruction) and facilitate biogas generation potential. A lab-scale wet air oxidation reactor with biomethanated distillery wastewater (B-DWW) as a model complex effluent (COD 40,000 mg L(-1)) was used to demonstrate the proof-of-concept. The studies were conducted using a designed set of experiments and reaction temperature (150-200°C), air pressure (6-12 bar) and reaction time (15-120 min) were the main process variables of concern for WAO process optimization. WAO pretreatment of B-DWW enhanced the biodegradability of the complex wastewater by the virtue of enhancing its biodegradability index (BI) from 0.2 to 0.88, which indicate favorable Biochemical Methane Potential (BMP) for biogas generation. The kinetics of COD destruction and BI enhancement has also been reported.

  15. 137Cs in recent tsunami deposits - a potential tracer of selective tsunami sediment entrainment?

    Science.gov (United States)

    Spiske, M.; Bahlburg, H.; Suckow, A.

    2012-12-01

    to the upper part that may be composed of material from mainly marine sources. The sediments constituting the upper part of the tsunami deposit may have been stored in shallow marine environments for more than ca. 60 years. Hence, they do not exhibit 137Cs and were not affected by later Cs-fallout because the nuclides were diluted in the sea water. Two transport scenarios for the 2010 Chile tsunami at La Trinchera seem to be possible: 1) The head of an individual onshore flowing wave of the tsunami wave train picked up both beach sand and onshore sediments, whereas the tail entrained shallow marine sediments. As the front of the wave decelerated during its inland flow, these sediments with high Cs-contents were deposited first. Subsequently, marine sediments without a detectable Cs-content reached the shore with some time delay and were then deposited on top. 2) Assuming that a tsunami consists of several waves with different magnitudes, it is possible that an earlier, less energetic wave, entrained sediments onshore, mixed and deposited them. A later, more energetic wave was then able to entrain marine sediments and deposit them on top. Whichever scenario might be more realistic, the Cs-signal may help to document selective, time-dependent erosion and deposition during tsunami inundation.

  16. Toxicity, sublethal effects, and potential modes of action of select fungicides on freshwater fish and invertebrates

    Science.gov (United States)

    Elskus, Adria A.

    2012-01-01

    Despite decades of agricultural and urban use of fungicides and widespread detection of these pesticides in surface waters, relatively few data are available on the effects of fungicides on fish and invertebrates in the aquatic environment. Nine fungicides are reviewed in this report: azoxystrobin, boscalid, chlorothalonil, fludioxonil, myclobutanil, fenarimol, pyraclostrobin, pyrimethanil, and zoxamide. These fungicides were identified as emerging chemicals of concern because of their high or increasing global use rates, detection frequency in surface waters, or likely persistence in the environment. A review of the literature revealed significant sublethal effects of fungicides on fish, aquatic invertebrates, and ecosystems, including zooplankton and fish reproduction, fish immune function, zooplankton community composition, metabolic enzymes, and ecosystem processes, such as leaf decomposition in streams, among other biological effects. Some of these effects can occur at fungicide concentrations well below single-species acute lethality values (48- or 96-hour concentration that effects a response in 50 percent of the organisms, that is, effective concentration killing 50 percent of the organisms in 48 or 96 hours) and chronic sublethal values (for example, 21-day no observed adverse effects concentration), indicating that single-species toxicity values may dramatically underestimate the toxic potency of some fungicides. Fungicide modes of toxic action in fungi can sometimes reflect the biochemical and (or) physiological effects of fungicides observed in vertebrates and invertebrates; however, far more studies are needed to explore the potential to predict effects in nontarget organisms based on specific fungicide modes of toxic action. Fungicides can also have additive and (or) synergistic effects when used with other fungicides and insecticides, highlighting the need to study pesticide mixtures that occur in surface waters. For fungicides that partition to

  17. The Himalayas as a directional barrier to gene flow.

    Science.gov (United States)

    Gayden, Tenzin; Cadenas, Alicia M; Regueiro, Maria; Singh, Nanda B; Zhivotovsky, Lev A; Underhill, Peter A; Cavalli-Sforza, Luigi L; Herrera, Rene J

    2007-05-01

    indicates that the Himalayas have been permeable to dispersals from the east. These genetic patterns suggest that this cordillera has been a biased bidirectional barrier.

  18. Treeline dynamics with climate change at Central Nepal Himalaya

    Directory of Open Access Journals (Sweden)

    N. P. Gaire

    2013-10-01

    Full Text Available Global climate change has multidimensional impacts with several biological fingerprints, and treeline shifting in tandem with climate change is a widely observed phenomenon in various parts of the world. In Nepal several impacts of climate change on physical environments have been observed. However, studies on the biological impacts are lacking. This dendrochronological study was carried out at the treeline ecotone (3750–4003 m a.s.l. in the Kalchuman Lake (Kal Tal area of the Manaslu Conservation Area in central Nepal Himalaya with the aim to study the dynamic impact of climate change at the treeline. The study provides an insight into regeneration and treeline dynamics over the past 200 yr. Two belt transect plots (size: 20 m wide, >250 m long were laid covering forest line, treeline as well as tree species Abies spectabilis and Betula utilis was done and their tree-cores were collected. Stand character and age distribution revealed an occurrence of more matured B. utilis (max. age 198 yr old compared to A. spectabilis (max. age 160 yr. A. spectabilis contained an overwhelmingly high population (89% of younger plants (A. spectabilis at the rate of 2.61 m yr−1 since 1850 AD. The upper distribution limit of B. utilis was found stagnant in the past few decades. An increment in plant density as well as upward shifting in the studied treeline ecotones was observed. Thus, two species presented species-specific responses to climate change and much wider differences anticipated in their population status as climate continues to cha spectabilis correlated negatively with the mean monthly temperature of May–August of the current year and with September of the previous year. The regeneration of A. spectabilis, on the other hand, was positively related with May–August precipitation and January–April temperature of the current year. The reconstructed average summer temperature (May–August using tree ring data revealed alternate period of cool

  19. [Selection of winter plant species for wetlands constructed as sewage treatment systems and evaluation of their wastewater purification potentials].

    Science.gov (United States)

    Chen, Yong-hua; Wu, Xiao-fu; Chen, Ming-li; Jiang, Li-juan; Li, Ke-lin; Lei, Dian; Wang, Hai-bin

    2010-08-01

    In order to establish an evaluation system for selection of winter wetland plants possessing high wastewater purification potentials in subtropics areas, designed sewage treatment experiments were carried out by introducing into the constructed wetlands 25 species of winter wetland plants. Cluster analysis was performed by including harmful environment-resistant enzyme and substrate enzyme activities into the commonly applied plant screening and assessment indexes system. The obtained results indicated that there were significant differences among the tested winter plants in their root length and vigor, leaf malonaldehyde (MDA), biomass, average nitrogen and phosphorus concentration and uptake, and urease and phosphoric acid enzyme activities in the root areas. Based on the established evaluation system, the tested plants were clustered into 3 groups. The plants in the 1st group possessing high purification potentials are Oenanthe javanica, Brassicacapestris, Juncus effusu, Saxifragaceae, Iris pseudoacorus, Osmanthus fragrans and Iris ensata; those in the 2nd group possessing moderate purification potentials are Brassica oleracea var acephala, Calendula officinalis, Aucuba japonica, Ligustrum lucidu, Beta vulgaris, Rhododendron simsii and Ilex latifolia; and those in the 3rd group with low purification potentials are Brassica oleracea var acephala, Calistephus chinensis, Rosa chinensis, Antirrhinums, Liriope palatyphylla, Zephyranthes candida, Fatshedera lizei, Petunia hybrida, Ilex quihoui, Dianthus caryophyllus and Loropetalum chinensis.

  20. [Selection and purification potential evaluation of woody plant in vertical flow constructed wetlands in the subtropical area].

    Science.gov (United States)

    Chen, Yong-Hua; Wu, Xiao-Fu; Hao, Jun; Chen, Ming-Li; Zhu, Guang-Yu

    2014-02-01

    In order to solve the problem that wetland herbaceous plants tend to die during winter in subtropics areas, selection and purification potential evaluation experiments were carried out by introducing into the constructed wetlands 16 species of woody wetland plants. Cluster analysis was performed by including the morphological characteristics, physiological characteristics, as well as nitrogen and phosphorus accumulation of the woody wetland plants. The results indicated that there were significant differences among the tested woody plants in their survival rate, height increase, root length increase and vigor, Chlorophyll content, Superoxide dismutase, Malonaldehyde, Proline, Peroxidase, biomass, average concentration and accumulation of nitrogen and phosphorus. Based on the established evaluation system, the tested plants were clustered into 3 groups. The plants in the 1st group possessing high purification potentials are Nerium oleander and Hibiscus syriacus. Those in the 2nd group possessing moderate purification potentials are Trachycarpus fortune, Llex latifolia Thunb., Gardenia jasminoides, Serissa foetida and Ilex crenatacv Convexa. And those in the 3rd group with low purification potentials are Jasminum udiflorum, Hedera helix, Ligustrum vicaryi, Ligustrum lucidum, Buxus sempervives, Murraya paniculata, Osmanthus fragrans, Mahoniafortune and Photinia serrulata.

  1. Glacier-induced Hazards in the Trans-Himalaya of Ladakh (NW-India)

    Science.gov (United States)

    Schmidt, Susanne; Dame, Juliane; Nüsser, Marcus

    2016-04-01

    Glaciers are important water resources for irrigated crop cultivation in the semi-arid Trans-Himalaya of Ladakh (NW-India). Due to global warming, many glaciers of South Asia have retreated over the last century and further ice loss will threaten local livelihoods in the long run. In the short term, an increase of flood events caused by melting glaciers and permafrost is expected for the Himalayan region. Beside large catastrophic events, small outburst floods are 'more' regularly reported for various parts of the region. This also holds true for the Trans-Himalayan region of Ladakh, where small glaciers exist at high altitudes. Caused by glacier retreat, a number of proglacial lakes have been formed, most of them dammed by ice filled moraines. The potential risk of these lakes is shown by recent reports on glacial lake outburst flood in the villages Nidder in October 2010 and Gya in August 2014. The 2014 flood destroyed several agricultural terraces, a new concrete bridge and two houses. Own remote sensing analyses shows the increase of a moraine dammed proglacial lake in the upper catchment area, which grew from about 0.03 to 0.08 km2 between 1969 and 2014. Because of the relatively stable altitude of the lake level, one can assume that the flood was caused by a piping process, initiated by melted ice bodies in the moraine. Already in the 1990s a small GLOF was observed in the village, which destroyed some fields. As in 2014, the lake was not completely spilled and a short-term decrease of the lake area is detectable in remote sensing data. Thus, further GLOF-events can be expected for the future. Beside physical risk factors, population growth and new infrastructure development along the streams and valleys increases potential damages of floods. Therefore, investigations are required to estimate the risks of these small glacial lakes and the potential flood effected area for the case study of Gya as well as for the whole region of Ladakh. Remote sensing data are

  2. Isolation gowns in health care settings: Laboratory studies, regulations and standards, and potential barriers of gown selection and use

    Science.gov (United States)

    Kilinc Balci, F. Selcen

    2016-01-01

    Although they play an important role in infection prevention and control, textile materials and personal protective equipment (PPE) used in health care settings are known to be one of the sources of cross-infection. Gowns are recommended to prevent transmission of infectious diseases in certain settings; however, laboratory and field studies have produced mixed results of their efficacy. PPE used in health care is regulated as either class I (low risk) or class II (intermediate risk) devices in the United States. Many organizations have published guidelines for the use of PPE, including isolation gowns, in health care settings. In addition, the Association for the Advancement of Medical Instrumentation published a guidance document on the selection of gowns and a classification standard on liquid barrier performance for both surgical and isolation gowns. However, there is currently no existing standard specific to isolation gowns that considers not only the barrier resistance but also a wide array of end user desired attributes. As a result, infection preventionists and purchasing agents face several difficulties in the selection process, and end users have limited or no information on the levels of protection provided by isolation gowns. Lack of knowledge about the performance of protective clothing used in health care became more apparent during the 2014 Ebola epidemic. This article reviews laboratory studies, regulations, guidelines and standards pertaining to isolation gowns, characterization problems, and other potential barriers of isolation gown selection and use. PMID:26391468

  3. Evaluation of phenolic content variability, antioxidant, antimicrobial and cytotoxic potential of selected traditional medicinal plants from India

    Directory of Open Access Journals (Sweden)

    Garima eSingh

    2016-03-01

    Full Text Available Plants have been used since ancient times as an important source of biologically active substances. The aim of the present study was to investigate the phytochemical constituents (flavonoids and phenolics, antioxidant potential, cytotoxicity against HepG2 (human hepato carcinoma cancer cell lines and the antimicrobial activity of the methanol extract of selected traditional medicinal plants collected from Mizoram, India. A number of phenolic compounds were detected using HPLC-DAD-ESI-TOF-MS, mainly Luteolin, Kaempferol, Myricetin, Gallic Acid, Quercetin and Rutin, some of which have been described for the first time in the selected plants. The total phenolic and flavonoid contents showed high variation ranging from 4.44 to 181.91 µg of Gallic Acid equivalent per milligram DW (GAE/mg DW and 3.17 to 102.2 µg of Quercetin/mg, respectively. The antioxidant capacity was determined by DPPH (IC50 values ranges from 34.22 to 131.4 µg/mL, ABTS (IC50 values ranges from 24.08 to 513.4 µg/mL and reducing power assays. Antimicrobial activity was assayed against gram positive (Staphylococcus aureus, gram negative (Escherichia coli, Pseudomonas aeruginosa and yeast (Candida albicans demonstrating that the methanol extracts of some plants were efficacious antimicrobial agents. Additionally, cytotoxicity was assessed on human hepato carcinoma (HepG2 cancer cell lines and found that the extracts of Albizia lebbeck, Dillenia indica and Bombax ceiba significantly decreased the cell viability at low concentrations with IC50 values of 24.03, 25.09 and 29.66 µg/mL, respectively. This is the first report of detection of phenolic compounds along with antimicrobial, antioxidant and cytotoxic potential of selected medicinal plants from India, which indicates that these plants might be valuable source for human and animal health.

  4. Predicting Monsoonal-Driven Stream Discharge and Sediment Yield in Himalaya Mountain Basins with Changing Climate and Deforestation

    Science.gov (United States)

    Neupane, R. P.; White, J. D.

    2014-12-01

    Short and long term effects of site water availability impacts the spectrum of management outcomes including landslide risk, hydropower generation, and sustainable agriculture in mountain systems heavily influenced by climate and land use changes. Climate change and land use may predominantly affect the hydrologic cycle of mountain basins as soil precipitation interception is affected by land cover. Using the Soil and Water Assessment Tool, we estimated stream discharge and sediment yield associated with climate and land use changes for two Himalaya basins located at eastern and western margins of Nepal that included drainages of the Tamor and Seti Rivers. Future climate change was modeled using average output of temperature and precipitation changes derived from Special Report on Emission Scenarios (B1, A1B & A2) of 16 global circulation models for 2080 as meteorological inputs into SWAT. Land use change was modeled spatially and included 1) deforestation, 2) expansion of agricultural land, and 3) increased human settlement that were produced by considering current land use with projected changes associated with viability of elevation and slope characteristics of the basins capable of supporting different land use types. We found higher annual stream discharge in all GCM-derived scenarios compared to the baseline with maximum increases of 13 and 8% in SRES-A2 and SRES-A1B for the Tamor and Seti basins, respectively. With 7% of original forest land removed, sediment yield for Tamor basin was estimated to be 65% higher, but increased to 124% for the SRES-B1 scenario. For the Seti basin, 4% deforestation yielded 33% more sediment for the SRES-A1B scenario. Our results indicated that combined effects of future, intensified monsoon rainfall with deforestation lead to dramatic potential for increased stream discharge and sediment yield as rainfall on steep slopes with thin exposed soils increases surface runoff and soil erosion in the Himalayas. This effect appears to

  5. Moraine-dammed glacial lake changes during the recent 40 years in the Poiqu River Basin, Himalayas

    Institute of Scientific and Technical Information of China (English)

    XiuJuan Zhang; ShiYin Liu; Li Liu

    2015-01-01

    Glacier retreat is not only a symbol of temperature and precipitation change, but a dominating factor of glacial lake changes in alpine regions, which are of wide concern for high risk of potential outburst floods. Of all types of glacial lakes, moraine-dammed lakes may be the most dangerous to local residents in mountain regions. Thus, we monitored the dy-namics of 12 moraine-dammed glacial lakes from 1974 to 2014 in the Poiqu River Basin of central west Himalayas, as well as their associated glaciers with a combination of remote sensing, topographic maps and digital elevation models (DEMs). Our results indicate that all monitored moraine-dammed glacial lakes have expanded by 7.46 km2 in total while the glaciers retreated by a total of 15.29 km2 correspondingly. Meteorological analysis indicates a warming and drying trend in the Nyalam region from 1974 to 2014, which accelerated glacier retreat and then augmented the supply of moraine-dammed glacial lakes from glacier melt. Lake volume and water depth changed from 1974 to 2014 which indicates that lakes Kangxico, Galongco, and Youmojanco have a high potential for outburst floods and in urgent need for continuous moni-toring or artificial excavation to release water due to the quick increase in water depths and storage capacities. Lakes Jialongco and Cirenmaco, with outburst floods in 1981 and 2002, have a high potential risk for outburst floods because of rapid lake growth and steep slope gradients surrounding them.

  6. Interpretation of Gravity Data using 3D Euler Deconvolution, Tilt Angle, Horizontal Tilt Angle and Source Edge Approximation of the North-West Himalaya

    Science.gov (United States)

    Ghosh, Gopal K.

    2016-08-01

    The collision of the Indian plate and the Eurasian plate created shortening and imbrications with thrusting and faulting which influences northward tectonic movement. This plate movement has divided the Himalaya into four parts, viz. Outer Himalaya, Lesser Himalaya, Greater Himalaya, and Tethys Himalaya. The crystalline basement rock plays an imperative role for structural and tectonic association. The study has been carried out near Rishikesh-Badrinath neighborhood in the northwestern part of the Himalayan girdle with multifarious tectonic set up with thrusted and faulted geological setting. In this study area, 3D Euler deconvolution, horizontal gradient analysis, tilt angle (TILT) and horizontal tilt angle (TDX) analysis have been carried out using gravity data to delineate the subsurface geology and heterogeneity in the northwestern part of Himalaya. The Euler depth solutions suggest the source depth of about 12 km and various derivative analyses suggest the trend of the delineation thrust-fault boundaries along with the dip and strike direction in the study area.

  7. Thermal supplementing soil nutrients through biocomposting of night-soil in the northwestern Indian Himalaya.

    Science.gov (United States)

    Oinam, Santaram S; Rawat, Yashwant S; Kuniyal, Jagdish C; Vishvakarma, S C R; Pandey, Dinesh C

    2008-01-01

    Agriculture is one of the prime activities of the hill people residing in the northwestern Indian Himalaya. However, poor soil fertility in these areas is a big hurdle to sustainable farming. The effects of washout of topsoil and its nutrients, year after year, due to the abundance of snowfall, avalanches, landslides and erosion further add to the woes of the farmers. In the cold and harsh climatic conditions of the region, with grass and vegetation cover being scanty, it is not possible to maintain large herds of cattle for the adequate production of farmyard manure. Faced with this situation, the locals have relied heavily on obtaining organic manure derived from composting of human excreta. In earlier times the dire necessity of the farmers helped them overcome the revulsion associated with the practice of handling human excreta, but now with the advent of modernisation and the easy availability of chemical fertilisers, the people are distancing themselves from this age-old practice. More and more people are opting for modern toilets and leaving behind the traditional toilets that made possible the harvesting of manure from night-soil. As a result, this primitive practice is on the verge of extinction. This eco-friendly practice, that has sustained the land for so many generations, needs to be continued and strengthened as the long-term consequences of excessive and indiscriminant use of chemical fertilisers are becoming too obvious to ignore. Traditional knowledge needs to be combined with modern scientific know-how to make this practice safer and more acceptable. If the composting operation is managed properly, the handling will be less loathsome and the concerns of health and hygiene too will stand addressed. The present study attempts a detailed profile of the practice of 'supplementing soil nutrients through biocomposting of night-soil' in the cold desert region of Lahaul Valley. Four villages running from the northwestern part to the southeastern part of

  8. Glacier length, area and volume changes in the Himalaya: an overview and specific examples

    Science.gov (United States)

    Bolch, T.; Bhambri, R.; Kamp, U.; Pieczonka, T.

    2011-12-01

    The Himalaya comprises one of the largest glacier-covered areas outside the polar regions. Glaciers are of special interest for several reasons. For instance, receding glaciers can cause the development of hazardous glacial lakes and glaciers contribute to the overall river runoff. The importance of the glacier melt to run off, however, varies significantly depending especially on the precipitation regime. Previous studies indicate that the vast majority of the Himalayan glaciers retreated during the recent decades with only few exemptions. Although the numbers of investigates glaciers increased in the last few years, there is still a lack of knowledge about the glacier behaviour in the different regions of the Himalaya. Existing length measurements in the Indian Himalaya show continuous retreat with an accelerating trend in recent years for most of the glaciers. The annual retreat rates vary between ~5m and more than 50m. However, several measurements are based on topographic maps or coarse satellite data and can have therefore higher uncertainties. Own reassessments for the debris-covered Gangotri Glacier situated in Garhwal Himalaya/western India based on high resolution imagery such as Corona, Hexagon, IRS PAN, LISS IV, and Cartosat-1 show an continuous retreat with an average rate of 19.9 ± 0.3 m a-1 from 1965 to 2006. This is significant but less than previously published. Similar results were revealed for the area changes in upper Alaknanda and Bhagirathi valleys in Garhwal Himalaya. We found a lower but still significant area loss of 4.6 ± 2.8 % between 1968 and 2006. Area changes in Khumbu Himalaya/Nepal are with ~5% between 1962 and 2005 comparable. Investigations in the Greater Himalayan Range in southern Ladakh/northwest India revealed a general receding trend but with some of the larger glaciers with high altitude catchments being stable or even advancing. Preliminary results for Shyok Valley (Jammu and Kashmir) show on average stable or slightly

  9. Sediment sources in a small agricultural catchment: A composite fingerprinting approach based on the selection of potential sources

    Science.gov (United States)

    Zhou, Huiping; Chang, Weina; Zhang, Longjiang

    2016-08-01

    Fingerprinting techniques have been widely used as a reasonable and reliable means for investigating sediment sources, especially in relatively large catchments in which there are significant differences in surface materials. However, the discrimination power of fingerprint properties for small catchments, in which the surface materials are relatively homogeneous and human interference is marked, may be affected by fragmentary or confused source information. Using fingerprinting techniques can be difficult, and there is still a need for further studies to verify the effectiveness of such techniques in these small catchments. A composite fingerprinting approach was used in this study to investigate the main sources of sediment output, as well as their relative contributions, from a small catchment (30 km2) with high levels of farming and mining activities. The impact of the selection of different potential sediment sources on the derivation of composite fingerprints and its discrimination power were also investigated by comparing the results from different combinations of potential source types. The initial source types and several samples that could cause confusion were adjusted. These adjustments improved the discrimination power of the composite fingerprints. The results showed that the composite fingerprinting approach used in this study had a discriminatory efficiency of 89.2% for different sediment sources and that the model had a mean goodness of fit of 0.90. Cultivated lands were the main sediment source. The sediment contribution of the studied cultivated lands ranged from 39.9% to 87.8%, with a mean of 76.6%, for multiple deposited sediment samples. The mean contribution of woodlands was 21.7%. Overall, the sediment contribution from mining and road areas was relatively low. The selection of potential sources is an important factor in the application of fingerprinting techniques and warrants more attention in future studies, as is the case with other

  10. Screening of Antioxidant Potential of Selected Barks of Indian Medicinal Plants by Multiple in vitro Assays LI

    Institute of Scientific and Technical Information of China (English)

    ARCHANA KUMARI; POONAM KAKKAR

    2008-01-01

    Objective To evaluate the antioxidant potential in herbal extract barks of five therapeutically important medicinal plants native to India,i.e.Crataeva nurvala Buch.-Ham.,Buchanania lanzan Spreng.,Aegle marmelos Corr.,Dalbergia sissoo Roxb.ex DC.,and Cedrela toona Roxb.Methods Standardized aqueous alcoholic extracts from the selected barks having different target radicals,such as superoxide radical,nitric oxide,ABTS radical,and peroxidative decomposition of phosphohpids.were prepared and screened bv multiple in vitro assays.These extracts were also tested for total phenolic and tannin content and correlated with antioxidant capacity. Results Tbtal phenolic and tannin contents were found to be the highest in C. nurvala (195 GAE mg/g and 218.3 mg/g CE).SOD mimetic activity was found to be the highest in Crataeva nurvula,although all barks showed activity more than 100 units/mg extract.Lipid peroxidation inhibitory potential was found to be the highest in Crataeva nurvala(83.4% inhibition of MDA formation/10 μg extract),and also showed a comparatively high NO quenching capacity (45.5% per 10 μg extract).The highest NO quenching potential was found in Aegle marmelos(47.3% per 10 μg extract).Cedrela toona showed the lowest LPO inhibitory potential and NO quenching capacity(50.5% and 30.5%,respectively).Buchanania lanzan,a medicinal plant extensively used for inflammatory disorders and Dalbergia sissoo also showed 72.5% and 69.1% LPO inhibitory potential/10 μg extract.Trolox equivalent antioxidant capacity ranged from 0.24 to 0.39 mmol/L TEAC/mg extract,indicating that all the barks tested had ABTS+ radical quenching capacity.Conclusion Bark of Crataeva nurvulahas the highest antioxidant capacity and a positive correlation between antioxidant activity and their plendic content was found.

  11. Selective serotonin re-uptake inhibitors potentiate gene blunting induced by repeated methylphenidate treatment: Zif268 versus Homer1a.

    Science.gov (United States)

    Van Waes, Vincent; Vandrevala, Malcolm; Beverley, Joel; Steiner, Heinz

    2014-11-01

    There is a growing use of psychostimulants, such as methylphenidate (Ritalin; dopamine re-uptake inhibitor), for medical treatments and as cognitive enhancers in the healthy. Methylphenidate is known to produce some addiction-related gene regulation. Recent findings in animal models show that selective serotonin re-uptake inhibitors (SSRIs), including fluoxetine, can potentiate acute induction of gene expression by methylphenidate, thus indicating an acute facilitatory role for serotonin in dopamine-induced gene regulation. We investigated whether repeated exposure to fluoxetine, in conjunction with methylphenidate, in adolescent rats facilitated a gene regulation effect well established for repeated exposure to illicit psychostimulants such as cocaine-blunting (repression) of gene inducibility. We measured, by in situ hybridization histochemistry, the effects of a 5-day repeated treatment with methylphenidate (5 mg/kg), fluoxetine (5 mg/kg) or a combination on the inducibility (by cocaine) of neuroplasticity-related genes (Zif268, Homer1a) in the striatum. Repeated methylphenidate treatment alone produced minimal gene blunting, while fluoxetine alone had no effect. In contrast, fluoxetine added to methylphenidate robustly potentiated methylphenidate-induced blunting for both genes. This potentiation was widespread throughout the striatum, but was most robust in the lateral, sensorimotor striatum, thus mimicking cocaine effects. For illicit psychostimulants, blunting of gene expression is considered part of the molecular basis of addiction. Our results thus suggest that SSRIs, such as fluoxetine, may increase the addiction liability of methylphenidate.

  12. High resolution WRF simulation of the spatiotemporal variability of precipitation over the Himalaya

    Science.gov (United States)

    Norris, J.; Carvalho, L. V.; Jones, C.; Cannon, F.; Bookhagen, B.

    2015-12-01

    The Himalaya enhances and redistributes large-scale precipitation systems associated with winter storms, the Indian monsoon, and other relevant weather systems through the year. The resulting runoff across the Himalaya is depended on by over a billion people in south Asia for energy, agriculture, industry, and human consumption. However, the observation and understanding of regional precipitation patterns are limited on account of sparse in-situ meteorological data and complex topography. Additionally, the region's extreme elevations pose significant challenges for remotely sensed observation and global reanalyses in accurately representing precipitation. Mesoscale simulations are therefore the best available option to determine precipitation patterns and evaluate water resources in the Himalaya. In this study, the Weather Research and Forecasting (WRF) model has been used to simulate the spatiotemporal distribution of precipitation over High Asia for a single, continuous hydrological year at high resolution (6.7 km). The output is compared to available high-elevation rain gauges along the Himalaya, as well as gridded precipitation estimates from the Tropical Rainfall Measuring Mission (TRMM) and satellite cloud-mask data from the Moderate Resolution Imaging Spectroradiometer (MODIS), to gauge the performance of the model in simulating the full annual range of precipitation systems over the Himalaya. WRF and TRMM show a similar inter-seasonal cycle of precipitation that appropriately represents climatic influences ranging from extratropical cyclones to the monsoon. Good agreement is also observed in the locations of precipitation maxima in transition months between the two regimes. WRF also compares well to daily in-situ precipitation throughout the year, with correlation coefficients generally at 0.5 and above, but decreasing for stations at increasingly high elevations. Diurnal cycles of precipitation during the monsoon are also similar between WRF and TRMM, with

  13. Land Use Changes in Himalaya and Their Impacts on Environment, Society and Economy: A Study of the Lake Region in Kumaon Himalaya, India

    Institute of Scientific and Technical Information of China (English)

    Prakash TIWARI

    2008-01-01

    The traditional resource use structure in Himalaya has transformed considerably during the recent past, mainly owing to the growth of population and the resultant increased demand of natural resources in the region. This transformation in resource use practices is particularly significant in the densely populated tracts of Himalaya. As a result, cultivated land, forests, pastures and rangelands have been deteriorated and depleted steadily and significantly leading to their conversion into degraded and non-productive lands. These rapid land use changes have not only disrupted the fragile ecological equilibrium in the mountains through indiscriminate deforestation, degradation of land resources and disruption of the hydrological cycle, but also have significant and irreversible adverse impacts on the rural economy, society, livelihood and life quality of mountain communities. It has been observed that the agricultural production has declined, water sources are drying up fast due to decreased ground water recharge and a large number of villages are facing enormous deficit of critical resources, such as food, fodder, firewood and water, mainly due to unabated deforestation. As a result, the rural people, particularly the women, have to travel considerably long distances to collect fodder and firewood and to fetching water. It is therefore highly imperative to evolve a comprehensive and integrated land use framework for the conservation of the biophysical environment and sustainable development of natural resources in Himalaya. The land use policy would help local communities in making use of their natural resources scientifically and judiciously, and thus help in the conservation of the biophysical environment and in the increasing of the productivity of natural resources. The study indicates that conservation of forests and other critical natural resources through community participation, generation of alternative means of livelihood, and employment in rural areas can

  14. Land use changes in Himalaya and their impacts on environment, society and economy: A study of the Lake Region in Kumaon Himalaya, India

    Science.gov (United States)

    Tiwari, Prakash

    2008-11-01

    The traditional resource use structure in Himalaya has transformed considerably during the recent past, mainly owing to the growth of population and the resultant increased demand of natural resources in the region. This transformation in resource use practices is particularly significant in the densely populated tracts of Himalaya. As a result, cultivated land, forests, pastures and rangelands have been deteriorated and depleted steadily and significantly leading to their conversion into degraded and non-productive lands. These rapid land use changes have not only disrupted the fragile ecological equilibrium in the mountains through indiscriminate deforestation, degradation of land resources and disruption of the hydrological cycle, but also have significant and irreversible adverse impacts on the rural economy, society, livelihood and life quality of mountain communities. It has been observed that the agricultural production has declined, water sources are drying up fast due to decreased ground water recharge and a large number of villages are facing enormous deficit of critical resources, such as food, fodder, firewood and water, mainly due to unabated deforestation. As a result, the rural people, particularly the women, have to travel considerably long distances to collect fodder and firewood and to fetching water. It is therefore highly imperative to evolve a comprehensive and integrated land use framework for the conservation of the biophysical environment and sustainable development of natural resources in Himalaya. The land use policy would help local communities in making use of their natural resources scientifically and judiciously, and thus help in the conservation of the biophysical environment and in the increasing of the productivity of natural resources. The study indicates that conservation of forests and other critical natural resources through community participation, generation of alternative means of livelihood, and employment in rural areas can

  15. Characterizing the impacts of water resources infrastructure, humans, and hydrologic nonstationarity on changes in flood risk across the Himalaya region

    Science.gov (United States)

    Tullos, D. D.

    2014-12-01

    As flood control infrastructure reaches its design life, and climate change, population growth, and urban migration increase flood risk, the historical paradigm of store-then-release floodwaters behind rigid infrastructure is of decreasing physical and socioeconomic value. Instead, a new paradigm of sustainable flood management is emerging, which can be framed in the context of three elements that can contribute to and/or mitigate flood risk: 1) water resources infrastructure, 2) policies and socioeconomics, and 3) changing climates and land use. In this presentation, I present the results of analysis on the role of these three elements in contributing to flood risk of the Sutlej River (India) and the Koshi River (Nepal) basins for six historical flood events. The Himalaya region was selected based on the a) increasing intensity of monsoonal rains, b) increasing prevalence of glacial lake outburst floods, c) water resources management that achieves short-term development goals but lacks long-term sustainability, and d) other socio-economic, environmental, and geopolitical factors. I develop and apply a flood risk management framework that is based on metrics for characterizing the losses associated with the three elements contributing to major floods in the Himalaya region. Derived from a variety of data sources, results highlight how, across different hydrogeologic settings and various flood magnitudes, the largest influences on high flood losses are associated with inflexible water resources infrastructure and inappropriate development and flood management policies. Particularly for the most destructive events, which are generally associated with landslides and other natural hazards in this region, the effectiveness of some types of traditional and inflexible flood management infrastructure, including large dams and levees, is limited. As opposed to the probability of a particular flood event, findings illustrate the importance of the damages side of the flood

  16. Genetic basis of interindividual susceptibility to cancer cachexia: selection of potential candidate gene polymorphisms for association studies

    Indian Academy of Sciences (India)

    N. Johns; B. H. Tan; M. Macmillan; T. S. Solheim; J. A. Ross; V. E. Baracos; S. Damaraju; K. C. H. Fearon

    2014-12-01

    Cancer cachexia is a complex and multifactorial disease. Evolving definitions highlight the fact that a diverse range of biological processes contribute to cancer cachexia. Part of the variation in who will and who will not develop cancer cachexia may be genetically determined. As new definitions, classifications and biological targets continue to evolve, there is a need for reappraisal of the literature for future candidate association studies. This review summarizes genes identified or implicated as well as putative candidate genes contributing to cachexia, identified through diverse technology platforms and model systems to further guide association studies. A systematic search covering 1986–2012 was performed for potential candidate genes / genetic polymorphisms relating to cancer cachexia. All candidate genes were reviewed for functional polymorphisms or clinically significant polymorphisms associated with cachexia using the OMIM and GeneRIF databases. Pathway analysis software was used to reveal possible network associations between genes. Functionality of SNPs/genes was explored based on published literature, algorithms for detecting putative deleterious SNPs and interrogating the database for expression of quantitative trait loci (eQTLs). A total of 154 genes associated with cancer cachexia were identified and explored for functional polymorphisms. Of these 154 genes, 119 had a combined total of 281 polymorphisms with functional and/or clinical significance in terms of cachexia associated with them. Of these, 80 polymorphisms (in 51 genes) were replicated in more than one study with 24 polymorphisms found to influence two or more hallmarks of cachexia (i.e., inflammation, loss of fat mass and/or lean mass and reduced survival). Selection of candidate genes and polymorphisms is a key element of multigene study design. The present study provides a contemporary basis to select genes and/or polymorphisms for further association studies in cancer cachexia, and

  17. Genetic basis of interindividual susceptibility to cancer cachexia: selection of potential candidate gene polymorphisms for association studies.

    Science.gov (United States)

    Johns, N; Tan, B H; MacMillan, M; Solheim, T S; Ross, J A; Baracos, V E; Damaraju, S; Fearon, K C H

    2014-12-01

    Cancer cachexia is a complex and multifactorial disease. Evolving definitions highlight the fact that a diverse range of biological processes contribute to cancer cachexia. Part of the variation in who will and who will not develop cancer cachexia may be genetically determined. As new definitions, classifications and biological targets continue to evolve, there is a need for reappraisal of the literature for future candidate association studies. This review summarizes genes identified or implicated as well as putative candidate genes contributing to cachexia, identified through diverse technology platforms and model systems to further guide association studies. A systematic search covering 1986-2012 was performed for potential candidate genes / genetic polymorphisms relating to cancer cachexia. All candidate genes were reviewed for functional polymorphisms or clinically significant polymorphisms associated with cachexia using the OMIM and GeneRIF databases. Pathway analysis software was used to reveal possible network associations between genes. Functionality of SNPs/genes was explored based on published literature, algorithms for detecting putative deleterious SNPs and interrogating the database for expression of quantitative trait loci (eQTLs). A total of 154 genes associated with cancer cachexia were identified and explored for functional polymorphisms. Of these 154 genes, 119 had a combined total of 281 polymorphisms with functional and/or clinical significance in terms of cachexia associated with them. Of these, 80 polymorphisms (in 51 genes) were replicated in more than one study with 24 polymorphisms found to influence two or more hallmarks of cachexia (i.e., inflammation, loss of fat mass and/or lean mass and reduced survival). Selection of candidate genes and polymorphisms is a key element of multigene study design. The present study provides a contemporary basis to select genes and/or polymorphisms for further association studies in cancer cachexia, and

  18. Cytotoxic Potential and Molecular Characterization of Fungal Endophytes from Selected High Value Medicinal Plants of the Kashmir Valley - India.

    Science.gov (United States)

    Dar, R A; Qazi, P H; Saba, I; Rather, S A; Wani, Z A; Qazi, A K; Shiekh, A A; Manzoor, A; Hamid, A; Modae, D M

    2016-03-01

    The present study explores the fungal endophytes from selected high value medicinal plants to check their activities at in-vitro and in-vivo level. The in-vitro cytotoxicity of selected endophytes revealed potent growth inhibition against human cancer cell lines of leukemia (THP-1), lung (A549), prostate (PC-3), colon (Caco-2), neuroblastoma (IMR-32) and breast (MCF-7) at a concentration of 100 µg/ml. Among them the endophytic strains I. e., IIIM2, IIIM3, IIIM7 and IIIM8 showed most significant growth inhibition against colon (Caco-2), prostate (PC-3), lung (A549) and leukemia (THP-1) cancer cell lines. At the in-vivo level maximum (58.95%) tumor growth inhibition was documented with the extract of IIIM2 against Ehrlich Ascites Carcinoma mouse modal. All the potent fungal endophytic strains were characterized using ITS 4 and ITS 5 region sequencing and phylogenetic analysis was ascertained among them. This paper confirms the 2 elite endophytic fungal strains, IIIM2 and IIIM8, have the potential to act as a source of new anticancer compounds.

  19. Size-frequency analysis of petroleum accumulations in selected United States plays: potential analogues for frontier areas

    Science.gov (United States)

    Attanasi, E.D.; Freeman, P.A.

    2004-01-01

    This report presents the petroleum accumulation size-frequency relationships of selected mature plays assessed in the U.S. Geological Survey?s 1995 National Assessment of Oil and Gas Resources. The plays provide assessors with potential analogue models from which to estimate the numbers of undiscovered accumulations in medium and smaller size categories. Each play selected was required to have at least 50 discovered accumulations. Discovered accumulations plus the mean number of undiscovered accumulations equals the total accumulations assessed at the play level. There were 36 plays that met the criteria for oil accumulations and 25 plays that met the criteria for gas accumulations. Other properties of the plays such as primary trap type, lithology, depth, and hydrocarbon characteristics are also provided to assist the geologist in choosing an appropriate analogue. The text explains how the analogue size-frequency relationships can be used to estimate the number of small and medium size accumulations for frontier-area plays or partially explored plays in high cost areas. Although this document has been written in support of the Alaska North Slope Assessment, the basic size?frequency relationships provided are applicable elsewhere.

  20. Selection against glycosylation sites in potential target proteins of the general HMWC N-glycosyltransferase in Haemophilus influenzae.

    Science.gov (United States)

    Gawthorne, Jayde A; Tan, Nikki Y; Bailey, Ulla-Maja; Davis, Margaret R; Wong, Linette W; Naidu, Ranjitha; Fox, Kate L; Jennings, Michael P; Schulz, Benjamin L

    2014-03-14

    The HMWABC system of non-typeable Haemophilus influenzae (NTHi) encodes the HMWA adhesin glycoprotein, which is glycosylated by the HMWC glycosyltransferase. HMWC is a cytoplasmic N-glycosyltransferase, homologues of which are widespread in the Pasteurellaceae. We developed an assay for nonbiased detection of glycoproteins in NTHi based on metabolic engineering of the Leloir pathway and growth in media containing radiolabelled monosaccharides. The only glycoprotein identified in NTHi by this assay was HMWA. However, glycoproteomic analyses ex vivo in Escherichia coli showed that HMWC of NTHi was a general glycosyltransferase capable of glycosylating selected asparagines in proteins other than its HMWA substrate, including Asn78 in E. coli 30S ribosomal protein S5. The equivalent residue in S5 homologues in H. influenzae or other sequenced Pasteurellaceae genomes is not asparagine, and these organisms also showed significantly fewer than expected potential sites of glycosylation in general. Expression of active HMWC in E. coli resulted in growth inhibition compared with expression of inactive enzyme, consistent with glycosylation by HMWC detrimentally affecting the function of some E. coli proteins. Together, this supports the presence of a selective pressure in the Pasteurellaceae against glycosylation sites that would be modified by the general N-glycosyltransferase activity of HMWC.

  1. Potential social, institutional, and environmental impacts of selected energy-conservation measures in two Washington communities. [Seattle and Yakima

    Energy Technology Data Exchange (ETDEWEB)

    Edelson, E.; Olsen, M.

    1980-03-01

    The likely environmental, social, and institutional impacts of selected energy-conservation measures in two communities in Washington state are reported. The five conservation measures investigated in this study were: (1) retrofitting existing buildings; (2) district heating and Integrated Community Energy Systems (ICES); (3) small automobiles and vehicle redesign; (4) land-use and housing modifications; and (5) electric-utility rate reform. Twenty potential impact areas were selected for analysis. These areas were divided into five categories of environmental impacts, economic impacts, community impacts, personal impacts, and overall quality of life in the community. The research was conducted in Seattle and Yakima, Washington. In each location, about two dozen public officials and business, labor, and community leaders were interviewed. Their diverse views are summarized. The Seattle respondents saw energy conservation as a highly desirable policy with a number of temporary, transitional problems arising as energy-conservation measures were implemented. Yakima respondents, in contrast, did not expect to encounter many serious energy problems in the foreseeable future and consequently viewed energy conservation as a relatively minor community concern. Moreover, they anticipated that many conservation measures, if implemented by the government, would encounter either apathy or resistance in their community. Two broad generalizations can bedrawn from these interviews: (1) energy conservation will basically be beneficial for the natural environment and our society; and (2) if energy conservation does become a dominant thrust in our society, it could stimulate and reinforce a much broader process of fundamental social change. (LCL)

  2. Geomorphic impacts, age and significance of two giant landslide dams in the Nepal Himalayas: Ringmo-Phoksundo (Dolpo District) and Dhampu-Chhoya (Mustang District).

    Science.gov (United States)

    Fort, Monique; Braucher, Regis; Bourlès, Didier; Guillou, Valery; Nath Rimal, Lila; Gribenski, Natacha; Cossart, Etienne

    2014-05-01

    Large catastrophic slope failures have recently retained much attention in the northern dry Himalayas (1). They play a prominent role in the denudation history of active orogens at a wide range of spatial and time scales (2), and they impact durably landforms and process evolution in upstream catchments. Their occurrence mostly results from three different potential triggers: earthquakes, post-glacial debuttressing, and permafrost melting. We focus on two examples of giant rock slope failures that occurred across and north of the Higher Himalaya of Nepal and assess their respective influence on the regional, geomorphic evolution. The Ringmo rockslide (4.5 km3) results from the collapse of a mountain wall (5148 m) cut into palaeozoic dolomites of the Tethysian Himalayas. It caused the damming of the Suli Gad River at the origin of the Phoksumdo Lake (3600 m asl). The presence of glacial till at the very base of the sequence suggests the rockslide event is post-glacial, a field assumption confirmed by cosmogenic dating. Two consistent 36Cl ages of 20,885 ±1675 argue for a single, massive event of paraglacial origin that fits well with the last chronologies available on the Last Glacial Maximum in the Nepal Himalaya. The persistence of the Phoksumdo Lake is due to its dam stability (i.e. high lime content of landslide components) and to low sediment flux from the arid, upper Suli Gad catchment. The Dhampu-Chhoya rock avalanche (about 1 km3, area extent 10 km2) was derived from the northward failure of the Kaiku ridge, uphold by north-dipping, upper crystallines of the Higher Himalaya. It dammed the Kali Gandaki River, with complex interactions with the Late Pleistocene ice tongues derived from the Dhaulagiri (8167 m) and Nilgiris (7061 m) peaks. Both the rock avalanche and glaciers controlled the existence and level of the "Marpha Lake" (lacustrine deposits up to Kagbeni). Again, consistent 10Be ages of 29,680 ± 1015 ka obtained from two large blocks (>1000 m3

  3. Study of seismicity in the NW Himalaya and adjoining regions using IMS network

    Science.gov (United States)

    Ali, Sherif M.; Shanker, D.

    2016-08-01

    The Reviewed Event Bulletin (REB) of the International Data Center (IDC) has been used in order to investigate the seismicity of the Northwest Himalaya and its neighboring region for the time period June 1999 to March 2015 within the geographical coordinates 25-40° N latitude and 65-85° E longitude. We have used a very precisely located earthquake dataset recorded by the International Monitoring System (IMS) Network containing 7,583 events with body wave magnitudes from 2.5 to 6.3. The study area has been subdivided into six regions based on the Flinn-Engdahl (F-E) seismic and geographical regionalization scheme, which was used as the region classifications of the International Data Center catalog. The examined region includes NW India, Pakistan, Nepal, Xizang, Kashmir, and Hindukush. For each region, Magnitudes of completeness (Mc) and Gutenberg-Richter (GR) recurrence parameters (a and b values) have been estimated. The Gutenberg-Richter analysis is preceded by an overview of the seismotectonics of the study area. The obtained Mc values vary from 3.5 to 3.9. The lower value of Mc was found mainly in Xizang region whereas the higher Mc threshold is evident in Pakistan region. However, the b values vary from 1.19 to 1.48. The lowest b value is recorded in Xizang region, which is mostly related to the Main Karakoram Thrust (MKT) fault, whereas the highest b values are recorded in NW India and Kashmir regions, which are mostly related to the Main Frontal Thrust (MFT) fault. The REB for the selected period has been compared to the most renowned bulletin of global seismicity, namely that issued by the National Earthquake Information Center (NEIC) of the United States Geological Survey (USGS). A study of 4,821 events recorded by USGS in the study region indicates that about 36 % of seismic events were missed and the catalog is considered as complete for events with magnitudes ≥4.0. However, both a and b values are obviously higher than those of IMS catalog. The a

  4. Glass and Glass-Ceramic Materials from Simulated Composition of Lunar and Martian Soils: Selected Properties and Potential Applications

    Science.gov (United States)

    Ray, C. S.; Sen, S.; Reis, S. T.; Kim, C. W.

    2005-01-01

    In-situ resource processing and utilization on planetary bodies is an important and integral part of NASA's space exploration program. Within this scope and context, our general effort is primarily aimed at developing glass and glass-ceramic type materials using lunar and martian soils, and exploring various applications of these materials for planetary surface operations. Our preliminary work to date have demonstrated that glasses can be successfully prepared from melts of the simulated composition of both lunar and martian soils, and the melts have a viscosity-temperature window appropriate for drawing continuous glass fibers. The glasses are shown to have the potential for immobilizing certain types of nuclear wastes without deteriorating their chemical durability and thermal stability. This has a direct impact on successfully and economically disposing nuclear waste generated from a nuclear power plant on a planetary surface. In addition, these materials display characteristics that can be manipulated using appropriate processing protocols to develop glassy or glass-ceramic magnets. Also discussed in this presentation are other potential applications along with a few selected thermal, chemical, and structural properties as evaluated up to this time for these materials.

  5. Captured by the pain: pain steady-state evoked potentials are not modulated by selective spatial attention.

    Science.gov (United States)

    Blöchl, Maria; Franz, Marcel; Miltner, Wolfgang H R; Weiss, Thomas

    2015-04-07

    Attention has been shown to affect the neural processing of pain. However, the exact mechanisms underlying this modulation remain unknown. Here, we used a new method called pain steady-state evoked potentials (PSSEPs) to investigate whether selective spatial attention affects EEG responses to tonic painful stimuli. In general, steady-state evoked potentials reflect changes in the EEG spectrum at a certain frequency that correspond to the frequency of a train of applied stimuli. In this study, high intensity transcutaneous electrical stimulation was delivered to both hands simultaneously with 31 Hz and 37 Hz, respectively. Subject׳s attention was directed to one of the two trains of stimulation in order to detect a small gap that was occasionally interspersed into the stimulus trains. Thereby, they had to ignore the stimulation applied to the other hand. Results show that PSSEPs were induced at 31 Hz and 37 Hz at frontal and central electrodes. PSSEPs occurred contralaterally to the respective hand stimulated with that frequency. Surprisingly, the magnitude of PSSEPs was not modulated by spatial attention towards one of the two stimuli. Our results indicate that attention can hardly be shifted between two simultaneously applied tonic painful stimulations.

  6. Risk assessment of children’s exposure to potentially harmful elements (PHE in selected urban parks of the Silesian agglomeration

    Directory of Open Access Journals (Sweden)

    Kicińska Alicja

    2016-01-01

    Full Text Available The author determined the total contents of selected elements potentially hazardous for health (PHE: As, Be, Cd, Co, Cu, Ni and Sn in soils, sand of sandboxes and airborne dust collected in three urban parks of the Silesian agglomeration. The upper limit of Cd content (a Polish regulation was exceeded in the soils of two largest and most frequented parks, the Silesian Park and the Kościuszko Park. The mean Cd contents in soils are 9 and 7 mg/kg, respectively. The metal contents of the sand from sandboxes are generally much lower than those of the soils: Cu 28 times on average, As 13 times, and Cd and Ni around 4 times, while the Co and Sn contents of sand are comparable with those of soils. Airborne dusts are a significant source of metals: they contain Cd (1–20 mg/kg, Co (2–17 mg/kg and Cu (6–143 mg/kg. The quotients of the health risk indicate a potential health risk caused by As, Cd and Ni for children, particularly those with a low (below 15 kg body weight. The risk level of 1–4% PTMDI (Provisional Maximum Tolerable Daily Intake origins from an accidental swallowing of soil.

  7. Seismic source zoning and maximum credible earthquake prognosis of the Greater Kashmir Territory, NW Himalaya

    Science.gov (United States)

    Sana, Hamid; Nath, Sankar Kumar

    2016-09-01

    We present the seismic source zoning of the tectonically active Greater Kashmir territory of the Northwestern Himalaya and seismicity analysis (Gutenberg-Richter parameters) and maximum credible earthquake (m max) estimation of each zone. The earthquake catalogue used in the analysis is an extensive one compiled from various sources which spans from 1907 to 2012. Five seismogenic zones were delineated, viz. Hazara-Kashmir Syntaxis, Karakorum Seismic Zone, Kohistan Seismic Zone, Nanga Parbat Syntaxis, and SE-Kashmir Seismic Zone. Then, the seismicity analysis and maximum credible earthquake estimation were carried out for each zone. The low b value (methodologies, the fault parameter approach, convergence rates using geodetic measurements, and the probabilistic approach using the earthquake catalogue and is estimated to be M w 7.7, M w 8.5, and M w 8.1, respectively. The maximum credible earthquake (m max) estimated for each zone shows that Hazara Kashmir Syntaxis Seismic Zone has the highest m max of M w 8.1 (±0.36), which is espoused by the historical 1555 Kashmir earthquake of M w 7.6 as well as the recent 8 October 2005 Kashmir earthquake of M w 7.6. The variation in the estimated m max by the above discussed methodologies is obvious, as the definition and interpretation of the m max change with the method. Interestingly, historical archives (˜900 years) do not speak of a great earthquake in this region, which is attributed to the complex and unique tectonic and geologic setup of the Kashmir Himalaya. The convergence is this part of the Himalaya is distributed not only along the main boundary faults but also along the various active out-of-sequence faults as compared to the Central Himalaya, where it is mainly adjusted along the main boundary fault.

  8. Black Carbon Flux Across the Himalaya through the Kali Gandaki Valley in Nepal

    Science.gov (United States)

    Dhungel, S.; Panday, A. K.; Mahata, K. S.

    2013-12-01

    Significant increases in black carbon concentration have been observed in the recent years over the Indo-Gangetic plain, the foothills of the Himalaya, as well as the high Himalaya and the Tibetan Plateau. The concentration of increased black carbon can be significantly correlated to the albedo effect and the warming of atmosphere at high altitudes due to the deposition of black carbon in the snow clad mountains. It is hypothesized that this deposition contributes to increased melting of Himalayan glaciers and snowfields. Satellite images show increasing amounts of aerosol haze over the Indo-Gangetic plains which penetrate into the Himalayan valleys. But how does it reach the high altitude of the Himalayan cryosphere? To date, mechanisms of transport upwind of the valley from the Indo-Gangetic plains up to the Himalaya have not been thoroughly investigated. We hypothesize that wind systems in the deep river valleys that cut across the Himalaya, such as the Arun valley and Kali Gandaki valley, serve as important pathways for pollutant transport. In 2010 the University of Virginia, in collaboration with ICIMOD and Nepal Wireless, established an atmospheric research station in Jomsom, Nepal (28.78N, 83.42E, 2900 m.a.s.l.). The station is equipped to measure black carbon (BC), carbon monoxide (CO), and ozone concentrations. It also has an automated weather station, a filter sampler, and a NASA Aeronet Sunphotometer. Here we use our observations in Jomsom to present an estimate of the annual flux of black carbon from the Indo-Gangetic plains to the Tibetan Plateau through the Kali Gandaki valley. In this way, we gain insight into the significance of deep valleys and their role as pathways for pollutant transport.

  9. Origin and radiative forcing of black carbon transported to the Himalayas and Tibetan Plateau

    Science.gov (United States)

    Kopacz, M.; Mauzerall, D. L.; Wang, J.; Leibensperger, E. M.; Henze, D. K.; Singh, K.

    2011-03-01

    The remote and high elevation regions of central Asia are influenced by black carbon (BC) emissions from a variety of locations. BC deposition contributes to melting of glaciers and questions exist, of both scientific and policy interest, as to the origin of the BC reaching the glaciers. We use the adjoint of the GEOS-Chem model to identify the location from which BC arriving at a variety of locations in the Himalayas and Tibetan Plateau originates. We then calculate its direct and snow-albedo radiative forcing. We analyze the seasonal variation in the origin of BC using an adjoint sensitivity analysis, which provides a detailed map of the location of emissions that directly contribute to black carbon concentrations at receptor locations. We find that emissions from northern India and central China contribute the majority of BC to the Himalayas, although the precise location varies with season. The Tibetan Plateau receives most BC from western and central China, as well as from India, Nepal, the Middle East, Pakistan and other countries. The magnitude of contribution from each region varies with season and receptor location. We find that sources as varied as African biomass burning and Middle Eastern fossil fuel combustion can significantly contribute to the BC reaching the Himalayas and Tibetan Plateau. We compute radiative forcing in the snow-covered regions and find the forcing due to the BC induced snow-albedo effect to vary from 5-15 W m-2 within the region, an order of magnitude larger than radiative forcing due to the direct effect, and with significant seasonal variation in the northern Tibetan Plateau. Radiative forcing from reduced snow albedo likely accelerates glacier melting. Our analysis may help inform mitigation efforts to slow the rate of glacial melt by identifying regions that make the largest contributions to BC deposition in the Himalayas and Tibetan Plateau.

  10. Oblique convergence and slip partitioning in the NW Himalaya: Implications from GPS measurements

    Science.gov (United States)

    Kundu, Bhaskar; Yadav, Rajeev Kumar; Bali, Bikram Singh; Chowdhury, Sonalika; Gahalaut, V. K.

    2014-10-01

    We report GPS measurements of crustal deformation across the Kashmir Himalaya. We combined these results with the published results of GPS measurements from the Karakoram fault system and suggest that in the Kashmir Himalaya, the motion between the southern Tibet and India plate is oblique with respect to the structural trend. We estimated this almost north-south oblique motion to be 17 ± 2 mm/yr, which is partitioned between dextral motion of 5 ± 2 mm/yr on the Karakoram fault system and oblique motion of 13.6 ± 1 mm/yr with an azimuth of N198°E in the northwest-southeast trending Kashmir Himalayan frontal arc. Thus, the partitioning of the India-Southern Tibet oblique motion is partial in the Kashmir Himalayan frontal arc. However, in the neighboring Nepal Himalaya, there is no partitioning; the entire India-Southern Tibet motion of 19-20 mm/yr is arc normal and is accommodated entirely in the Himalayan frontal arc. The convergence rate in the Kashmir frontal Himalaya is about 25% less than that in the Nepal Himalayan region. However, here the Karakoram fault system accommodates about 20% of the southern Tibet and Indian plate convergence and marks the northern extent of the NW Himalayan arc sliver. The Kaurik Chango rift, a north-south oriented seismically active cross-wedge transtensional fault appears to divide the sliver in two parts causing varying translatory motion on the Karakoram fault on either side of the Kaurik Chango rift.

  11. Drymaria villosa (Caryophyllaceae new record for the flora of the Western Himalaya

    Directory of Open Access Journals (Sweden)

    Satish Chandra

    2016-03-01

    Full Text Available The herb Drymaria villosa is reported first time from the Western Himalaya. This species is morphologically similar to Drymaria cordata ssp. diandra but can be distinguished by its delicate individuals, villous vestiture, orbicular to reniform leaves, auriculate oblong bifid petals, and numerous reniform seeds. The present collection of the species represents westernmost distributional limit in the Asian continent. Morphological characteristics of the species were examined, which are illustrated here. Key to differentiate it from closely allied species is also provided.

  12. Origin and radiative forcing of black carbon transported to the Himalayas and Tibetan Plateau

    Directory of Open Access Journals (Sweden)

    M. Kopacz

    2011-03-01

    Full Text Available The remote and high elevation regions of central Asia are influenced by black carbon (BC emissions from a variety of locations. BC deposition contributes to melting of glaciers and questions exist, of both scientific and policy interest, as to the origin of the BC reaching the glaciers. We use the adjoint of the GEOS-Chem model to identify the location from which BC arriving at a variety of locations in the Himalayas and Tibetan Plateau originates. We then calculate its direct and snow-albedo radiative forcing. We analyze the seasonal variation in the origin of BC using an adjoint sensitivity analysis, which provides a detailed map of the location of emissions that directly contribute to black carbon concentrations at receptor locations. We find that emissions from northern India and central China contribute the majority of BC to the Himalayas, although the precise location varies with season. The Tibetan Plateau receives most BC from western and central China, as well as from India, Nepal, the Middle East, Pakistan and other countries. The magnitude of contribution from each region varies with season and receptor location. We find that sources as varied as African biomass burning and Middle Eastern fossil fuel combustion can significantly contribute to the BC reaching the Himalayas and Tibetan Plateau. We compute radiative forcing in the snow-covered regions and find the forcing due to the BC induced snow-albedo effect to vary from 5–15 W m−2 within the region, an order of magnitude larger than radiative forcing due to the direct effect, and with significant seasonal variation in the northern Tibetan Plateau. Radiative forcing from reduced snow albedo likely accelerates glacier melting. Our analysis may help inform mitigation efforts to slow the rate of glacial melt by identifying regions that make the largest contributions to BC deposition in the Himalayas and Tibetan Plateau.

  13. Phenotypic differentiation of Barilius bendelisis (Cypriniformes: Cyprinidae) in four rivers from Central Indian Himalaya

    OpenAIRE

    Iqbal Mir, Javaid; Saxena, Neha; Singh Patiyal, Rabindar; Kumari Sahoo, Prabhati

    2015-01-01

    Barilius bendelisis, commonly known as Indian Hill Trout is an upland water fish of South East Asia. It belongs to the family Cyprinidae and dwells in shallow, clear and cold water. In this study, the intraspecific variation of Barilius bendelisis, on the basis of morphometric characters, was investigated. Altogether, 402 specimens were collected from four rivers in the Central Indian Himalaya. A truss network was constructed by interconnecting 12 landmarks to yield 30 distance variables that...

  14. Glacial lake expansion in the central Himalayas by Landsat images, 1990-2010.

    Science.gov (United States)

    Nie, Yong; Liu, Qiao; Liu, Shiyin

    2013-01-01

    Glacial lake outburst flood (GLOF) is a serious hazard in high, mountainous regions. In the Himalayas, catastrophic risks of GLOFs have increased in recent years because most Himalayan glaciers have experienced remarkable downwasting under a warming climate. However, current knowledge about the distribution and recent changes in glacial lakes within the central Himalaya mountain range is still limited. Here, we conducted a systematic investigation of the glacial lakes within the entire central Himalaya range by using an object-oriented image processing method based on the Landsat Thematic Mapper (TM) or Enhanced Thematic Mapper (ETM) images from 1990 to 2010. We extracted the lake boundaries for four time points (1990, 2000, 2005 and 2010) and used a time series inspection method combined with a consistent spatial resolution of Landsat images that consistently revealed lake expansion. Our results show that the glacial lakes expanded rapidly by 17.11% from 1990 to 2010. The pre-existing, larger glacial lakes, rather than the newly formed lakes, contributed most to the areal expansion. The greatest expansions occurred at the altitudinal zones between 4800 m and 5600 m at the north side of the main Himalayan range and between 4500 m and 5600 m at the south side, respectively. Based on the expansion rate, area and type of glacial lakes, we identified 67 rapidly expanding glacial lakes in the central Himalayan region that need to be closely monitored in the future. The warming and increasing amounts of light-absorbing constituents of snow and ice could have accelerated the melting that directly affected the glacial lake expansion. Across the main central Himalayas, glacial lakes at the north side show more remarkable expansion than those at the south side. An effective monitoring and warning system for critical glacial lakes is urgently needed.

  15. Glacial lake expansion in the central Himalayas by Landsat images, 1990-2010.

    Directory of Open Access Journals (Sweden)

    Yong Nie

    Full Text Available Glacial lake outburst flood (GLOF is a serious hazard in high, mountainous regions. In the Himalayas, catastrophic risks of GLOFs have increased in recent years because most Himalayan glaciers have experienced remarkable downwasting under a warming climate. However, current knowledge about the distribution and recent changes in glacial lakes within the central Himalaya mountain range is still limited. Here, we conducted a systematic investigation of the glacial lakes within the entire central Himalaya range by using an object-oriented image processing method based on the Landsat Thematic Mapper (TM or Enhanced Thematic Mapper (ETM images from 1990 to 2010. We extracted the lake boundaries for four time points (1990, 2000, 2005 and 2010 and used a time series inspection method combined with a consistent spatial resolution of Landsat images that consistently revealed lake expansion. Our results show that the glacial lakes expanded rapidly by 17.11% from 1990 to 2010. The pre-existing, larger glacial lakes, rather than the newly formed lakes, contributed most to the areal expansion. The greatest expansions occurred at the altitudinal zones between 4800 m and 5600 m at the north side of the main Himalayan range and between 4500 m and 5600 m at the south side, respectively. Based on the expansion rate, area and type of glacial lakes, we identified 67 rapidly expanding glacial lakes in the central Himalayan region that need to be closely monitored in the future. The warming and increasing amounts of light-absorbing constituents of snow and ice could have accelerated the melting that directly affected the glacial lake expansion. Across the main central Himalayas, glacial lakes at the north side show more remarkable expansion than those at the south side. An effective monitoring and warning system for critical glacial lakes is urgently needed.

  16. Glacial Lake Expansion in the Central Himalayas by Landsat Images, 1990–2010

    Science.gov (United States)

    Nie, Yong; Liu, Qiao; Liu, Shiyin

    2013-01-01

    Glacial lake outburst flood (GLOF) is a serious hazard in high, mountainous regions. In the Himalayas, catastrophic risks of GLOFs have increased in recent years because most Himalayan glaciers have experienced remarkable downwasting under a warming climate. However, current knowledge about the distribution and recent changes in glacial lakes within the central Himalaya mountain range is still limited. Here, we conducted a systematic investigation of the glacial lakes within the entire central Himalaya range by using an object-oriented image processing method based on the Landsat Thematic Mapper (TM) or Enhanced Thematic Mapper (ETM) images from 1990 to 2010. We extracted the lake boundaries for four time points (1990, 2000, 2005 and 2010) and used a time series inspection method combined with a consistent spatial resolution of Landsat images that consistently revealed lake expansion. Our results show that the glacial lakes expanded rapidly by 17.11% from 1990 to 2010. The pre-existing, larger glacial lakes, rather than the newly formed lakes, contributed most to the areal expansion. The greatest expansions occurred at the altitudinal zones between 4800 m and 5600 m at the north side of the main Himalayan range and between 4500 m and 5600 m at the south side, respectively. Based on the expansion rate, area and type of glacial lakes, we identified 67 rapidly expanding glacial lakes in the central Himalayan region that need to be closely monitored in the future. The warming and increasing amounts of light-absorbing constituents of snow and ice could have accelerated the melting that directly affected the glacial lake expansion. Across the main central Himalayas, glacial lakes at the north side show more remarkable expansion than those at the south side. An effective monitoring and warning system for critical glacial lakes is urgently needed. PMID:24376778

  17. Origin and radiative forcing of black carbon transported to the Himalayas and Tibetan Plateau

    Directory of Open Access Journals (Sweden)

    M. Kopacz

    2010-09-01

    Full Text Available The remote and high elevation regions of central Asia are influenced by black carbon (BC emissions from a variety of locations. BC deposition contributes to melting of glaciers and questions exist, of both scientific and policy interest, as to the origin of the BC reaching the glaciers. We use the adjoint of the GEOS-Chem model to identify the location from which BC arriving at a variety of locations in the Himalayas and Tibetan Plateau originates. We then calculate its direct and snow-albedo radiative forcing. We analyze the seasonal variation in the origin of BC using an adjoint sensitivity analysis, which provides a detailed map of the location of emissions that directly contribute to black carbon concentrations at receptor locations. We find that emissions from northern India and central China contribute the majority of BC to the Himalayas, although the precise location varies with season. The Tibetan Plateau receives most BC from western and central China, as well as from India, Nepal, the Middle East, Pakistan and other countries. The magnitude of contribution from each region varies with season and receptor location. We find that sources as varied as African biomass burning and Middle Eastern fossil fuel combustion can significantly contribute to the BC reaching the Himalayas and Tibetan Plateau. We compute radiative forcing in the snow-covered regions and estimate the forcing due to the BC induced snow-albedo effect at about 5–15 W m−2 within the region, an order of magnitude larger than radiative forcing due to the direct effect, and with significant seasonal variation in the northern Tibetan Plateau. Radiative forcing from reduced snow albedo accelerates glacier melting. Our analysis can help inform mitigation efforts to slow the rate of glacial melt by identifying regions that make the largest contributions to BC deposition in the Himalayas and Tibetan Plateau.

  18. Glacial Lake Expansion in the Central Himalayas By Landsat Images, 1990-2010

    Science.gov (United States)

    Nie, Y.; Liu, Q.; Liu, S.

    2014-12-01

    Glacial lake outburst flood (GLOF) is a serious hazard in high, mountainous regions. In the Himalayas, catastrophic risks of GLOFs have increased in recent years because most Himalayan glaciers have experienced remarkable downwasting under a warming climate. However, current knowledge about the distribution and recent changes in glacial lakes within the central Himalaya mountain range is still limited. Here, we conducted a systematic investigation of the glacial lakes within the entire central Himalaya range by using an object-oriented image processing method based on the Landsat Thematic Mapper (TM) or Enhanced Thematic Mapper (ETM) images from 1990 to 2010. We extracted the lake boundaries for four time points (1990, 2000, 2005 and 2010) and used a time series inspection method combined with a consistent spatial resolution of Landsat images that consistently revealed lake expansion. Our results show that the glacial lakes expanded rapidly by 17.11% from 1990 to 2010. The pre-existing, larger glacial lakes, rather than the newly formed lakes, contributed most to the areal expansion. The greatest expansions occurred at the altitudinal zones between 4800 m and 5600 m at the north side of the main Himalayan range and between 4500 m and 5600 m at the south side, respectively. Based on the expansion rate, area and type of glacial lakes, we identified 67 rapidly expanding glacial lakes in the central Himalayan region that need to be closely monitored in the future. The warming and increasing amounts of light-absorbing constituents of snow and ice could have accelerated the melting that directly affected the glacial lake expansion. Across the main central Himalayas, glacial lakes at the north side show more remarkable expansion than those at the south side. An effective monitoring and warning system for critical glacial lakes is urgently needed.

  19. Construction and selection of subtracted cDNA library of mouse hepatocarcinoma cell lines with different lymphatic metastasis potential

    Institute of Scientific and Technical Information of China (English)

    Li Hou; Jan-Wu Tang; Xiao-Nan Cui; Bo Wang; Bo Song; Lei Sun

    2004-01-01

    AIM: In order to elucidate the molecular mechanism of lymphatic metastasis of hepatocarcinoma, we detected the difference of gene expression between mouse hepatocarcinoma cell lines Hca-F and Hca-P with different lymphatic metastasis potential.METHODS: cDNA of Hca-F cells was used as a tester and cDNA of Hca-P cells was used as a driver. cDNAs highly expressed in Hca-F cells were isolated by the suppression subtractive hybridization (SSH) method. The isolated cDNA was cloned into T/A cloning vector. The ligation products were transformed into DH5 α competent cells. Individual clones were randomly selected and used for PCR amplification.Vector DNA from positive clones was isolated for sequencing.RESULTS: There were 800 positive clones in amplified subtracted cDNA library. Random analysis of 160 clones with PCR showed that 95% of the clones contained 100-700 bp inserts. Analysis of 20 sequenced cDNA clones randomly picked from the SSH library revealed 4 known genes (mouse heat shock protein 84 ku, DNA helicase, ribosomal protein S13 ,ethanol induced 6 gene) and 3 expressed sequence tags (ESTs). Four cDNAs showed no homology and presumably represent novel genes.CONCLUSION: A subtracted cDNA library of differentially expressed genes in mouse heptocarcinoma cell lines with different lymphatic metastasis potential was successfully constructed with SSH and T/A cloning techniques. The library is efficient and lays a solid foundation for searching new lymphatic metastasis related genes. The expression of mouse heat shock protein gene, DNA helicase and other 4 novel gene may be different between mouse heptocarcinoma cell lines with different lymphatic metastasis potential.

  20. Interpreting the geomorphometric indices for neotectonic implications: An example of Alaknanda valley, Garhwal Himalaya, India

    Indian Academy of Sciences (India)

    Naresh Rana; Sunil Singh; Y P Sundriyal; G S Rawat; Navin Juyal

    2016-06-01

    Tectonic process can influence the erosion and exert the first order impression on hydrographic networkof an area. Geomorphometry, a mathematical analysis of the configuration of the landforms, allows quantifyingthe degree of landform evolution and is widely used as a measure of tectonic deformation/uplift.Alaknanda valley lies in the tectonically active Garhwal Himalaya which has experienced two disastrouslarge earthquakes in the last two decades. Morphometric analyses of the valley were carried out in a fluvialerosion dominated regime and the morphometric indices were derived from the ASTER (30 m × 30 mpixel) Digital Elevation Model (DEM) using Arc GIS. The results of the analyses reveal two zones ofhigh deformation/uplift in the valley, viz., the zone of high deformation proximal to the Main CentralThrust (MCT) in the Inner Lesser Himalaya (ILH) and the second zone of moderate deformation/upliftin the Outer Lesser Himalaya (OLH), south of the Tons Thrust (TT). The high deformation in the ILHis ascribed to the focussed convergence and high precipitation; however, the causes for the moderatedeformation in the OLH are yet to be established.

  1. Interpreting the geomorphometric indices for neotectonic implications: An example of Alaknanda valley, Garhwal Himalaya, India

    Science.gov (United States)

    Rana, Naresh; Singh, Sunil; Sundriyal, Y. P.; Rawat, G. S.; Juyal, Navin

    2016-06-01

    Tectonic process can influence the erosion and exert the first order impression on hydrographic network of an area. Geomorphometry, a mathematical analysis of the configuration of the landforms, allows quantifying the degree of landform evolution and is widely used as a measure of tectonic deformation/uplift. Alaknanda valley lies in the tectonically active Garhwal Himalaya which has experienced two disastrous large earthquakes in the last two decades. Morphometric analyses of the valley were carried out in a fluvial erosion dominated regime and the morphometric indices were derived from the ASTER (30 m × 30 m pixel) Digital Elevation Model (DEM) using Arc GIS. The results of the analyses reveal two zones of high deformation/uplift in the valley, viz., the zone of high deformation proximal to the Main Central Thrust (MCT) in the Inner Lesser Himalaya (ILH) and the second zone of moderate deformation/uplift in the Outer Lesser Himalaya (OLH), south of the Tons Thrust (TT). The high deformation in the ILH is ascribed to the focussed convergence and high precipitation; however, the causes for the moderate deformation in the OLH are yet to be established.

  2. Landslide Hazard Zonation and Risk Assessment of Ramganga Basin in Garhwal Himalaya

    Science.gov (United States)

    Wasini Pandey, Bindhy; Roy, Nikhil

    2016-04-01

    The Himalaya being unique in its physiographic, tectonic and climatic characteristics coupled with many natural and man-made factors is inherently prone to landslides. These landslides lead to mass loss of property and lives every year in Himalayas. Hence, Landslide Hazard Zonation is important to take quick and safe mitigation measures and make strategic planning for future development. The present study tries to explore the causes of landslides in Ramganga Basin in Garhwal Himalaya, which has an established history and inherent susceptibility to massive landslides has been chosen for landslide hazard zonation and risk assessment. The satellite imageries of LANDSAT, IRS P6, ASTER along with Survey of India (SOI) topographical sheets formed the basis for deriving baseline information on various parameters like slope, aspect, relative relief, drainage density, geology/lithology and land use/land cover. The weighted parametric method will be used to determine the degree of susceptibility to landslides. Finally, a risk map will be prepared from the landslide probability values, which will be classified into no risk, very low to moderate, high, and very high to severe landslide hazard risk zones. Keywords: Landslides, Hazard Zonation, Risk Assessment

  3. Precipitation variability in central Himalayas and its relation to Northern Hemisphere temperature

    Institute of Scientific and Technical Information of China (English)

    DUAN Keqin; YAO Tandong

    2003-01-01

    A 149.8-m-long ice core was drilled at the accumulation area of Dasuopu glacier (28°23′N, 85°43′E, 7100 m a.s.l.) in the central Himalayas in 1997. The ice core was analyzed continuously for stable isotopes (δ18O), cations (Na+, K+, Mg2+, Ca2+) and anions (Cl-,SO2-4,NO3-) throughout the core. Cycles indicated by δ18O, cations and anions were identified and counted as seasonal fluctuations as annual increment from maximum to maximum values. Reconstructed 300-year annual net accumulation from the core reveals a major precipitation trend for the central Himalayas with an average precipitation 750 mm per year. The trend, separated from the time series, shows a strong correlation to global temperature. Generally, as northern global temperature increases 0.1℃, the accumulation decreases about 80mm and vise versa. This may suggests that monsoon precipitation in Himalayas have decreased continuously in past decade as a response to global warming.

  4. Influence of regional precipitation patterns on stable isotopes in ice cores from the central Himalayas

    Directory of Open Access Journals (Sweden)

    H. Pang

    2013-05-01

    Full Text Available Several ice cores have been recovered from the Dasuopu Glacier and the East Rongbuk (ER Glacier in the central Himalayas since the 1990s. Although the distance between the ER and the Dasuopu ice core drilling sites is only ∼125 km, the stable isotopic record (δ18O or δD of the ER core is interpreted as a precipitation proxy while the Dasuopu core as a temperature proxy. Thus, the climatological significance of the stable isotopic records of these Himalayan ice cores remains a subject of debate. Based on analysis of regional precipitation patterns over the region, we find that the different interpretations of the Dasuopu and Everest isotopic records may not be contradictive. The north–south and west–east seesaws of the Indian Summer Monsoon (ISM precipitation are primarily responsible for precipitation falling at the ER site, which results in a negative correlation between the ER δ18O or δD record and precipitation amount along the southern slope of the central Himalayas, corresponding to the "amount effect". In addition to the ISM precipitation, non-summer monsoonal precipitation associated with winter westerlies also significantly contributes to precipitation falling at the Dasuopu site, which may cause a positive correlation between the Dasuopu stable isotopic record and temperature, in response to the "temperature effect". Our results have important implications for interpreting the stable isotopic ice core records recovered from different climatological regimes of the Himalayas.

  5. Focal depths and fault plane solutions of earthquakes and active tectonics of the Himalaya

    Science.gov (United States)

    Baranowski, J.; Armbruster, J.; Seeber, L.; Molnar, P.

    1984-01-01

    Synthetic seismograms were compared with long-period body waves for nine earthquakes with epicenters in the Himalayan arc to determine depths of foci and to improve fault plane solutions. Focal depths are shallow (10-20 km). Inferred slip vectors are locally perpendicular to the mountain range; they plunge very gently (about 10 deg) in the eastern sections of the range and more steeply (about 25 deg) in western sections. Assuming India to be a rigid plate, the radially oriented slip vectors imply that southern Tibet extends at about half the rate of underthrusting in the Himalaya and therefore probably at about 5-10 mm/yr. The shallow depths and gentle dips of the fault planes, at least for the events in the eastern half of the range, are consistent with coherent underthrusting of the Indian plate beneath, at least, the Lesser Himalaya. The steeper dips of fault planes in the western part of the arc might reflect deformation of the overriding thrust plate or simply a steepening of the main underthrusting zone beneath the Greater Himalaya.

  6. Westerly moisture transport to the middle of Himalayas revealed from the high deuterium excess

    Institute of Scientific and Technical Information of China (English)

    TIAN Lide; YAO Tandong; J.W.C.White; YU Wusheng; WANG Ninglian

    2005-01-01

    Previous studies found extremely high d-excess in both ice core and glacial melt water in Dasuopu glacier, Xixiabangma, middle of Himalayas. These values are much higher than the global average and those measured in southwest monsoon precipitation. The d-excess variation in over one year at Nyalam station will clarify this phenomenon. Studies show that the high d-excess is related to the seasonal variation of moisture transport to this region. The d-excess values are low during the southwest monsoon active periods, when moisture originated from the humid ocean surface. The d-excess values are higher in non-monsoon months, when moisture is derived from westerly transport. Winter and spring precipitation accounts for a substantial portion of the annual precipitation, resulting in higher d-excess in the yearly precipitation in the middle of Himalayas than other parts of the southern Tibetan Plateau. This finding reveals that the precipitation in the middle of Himalayas is not purely from southwest monsoon, but a large portion from the westerly transport, which is very important for ice core study in this area.

  7. A New Quaternary Strand of the Karakoram Fault System, Ladakh Himalayas

    Science.gov (United States)

    Bohon, W.; Hodges, K.; Arrowsmith, R.; Tripathy, A.

    2009-12-01

    , rather than one strand, suggests that previous estimates of total Karakoram fault system slip rates in this sector of the Himalaya may be too low. Efforts to determine the slip rate on the newly recognized active strand and to better quantify total slip rates are underway. Determining these rates is essential for answering first-order questions about the evolution and behavior of the Karakoram fault system in this region, the late-stage exhumation kinematics of the Pangong Range, and regional seismic hazard potential.

  8. Identifying potential selective fluorescent probes for cancer-associated protein carbonic anhydrase IX using a computational approach.

    Science.gov (United States)

    Kamstra, Rhiannon L; Floriano, Wely B

    2014-11-01

    Carbonic anhydrase IX (CAIX) is a biomarker for tumor hypoxia. Fluorescent inhibitors of CAIX have been used to study hypoxic tumor cell lines. However, these inhibitor-based fluorescent probes may have a therapeutic effect that is not appropriate for monitoring treatment efficacy. In the search for novel fluorescent probes that are not based on known inhibitors, a database of 20,860 fluorescent compounds was virtually screened against CAIX using hierarchical virtual ligand screening (HierVLS). The screening database contained 14,862 compounds tagged with the ATTO680 fluorophore plus an additional 5998 intrinsically fluorescent compounds. Overall ranking of compounds to identify hit molecular probe candidates utilized a principal component analysis (PCA) approach. Four potential binding sites, including the catalytic site, were identified within the structure of the protein and targeted for virtual screening. Available sequence information for 23 carbonic anhydrase isoforms was used to prioritize the four sites based on the estimated "uniqueness" of each site in CAIX relative to the other isoforms. A database of 32 known inhibitors and 478 decoy compounds was used to validate the methodology. A receiver-operating characteristic (ROC) analysis using the first principal component (PC1) as predictive score for the validation database yielded an area under the curve (AUC) of 0.92. AUC is interpreted as the probability that a binder will have a better score than a non-binder. The use of first component analysis of binding energies for multiple sites is a novel approach for hit selection. The very high prediction power for this approach increases confidence in the outcome from the fluorescent library screening. Ten of the top scoring candidates for isoform-selective putative binding sites are suggested for future testing as fluorescent molecular probe candidates.

  9. Characterization of the apoptotic response induced by the cyanine dye D112: a potentially selective anti-cancer compound.

    Directory of Open Access Journals (Sweden)

    Ning Yang

    Full Text Available Chemotherapeutic drugs that are used in anti-cancer treatments often cause the death of both cancerous and noncancerous cells. This non-selective toxicity is the root cause of untoward side effects that limits the effectiveness of therapy. In order to improve chemotherapeutic options for cancer patients, there is a need to identify novel compounds with higher discrimination for cancer cells. In the past, methine dyes that increase the sensitivity of photographic emulsions have been investigated for anti-cancer properties. In the 1970's, Kodak Laboratories initiated a screen of approximately 7000 dye structural variants for selective toxicity. Among these, D112 was identified as a promising compound with elevated toxicity against a colon cancer cell line in comparison to a non-transformed cell line. Despite these results changing industry priorities led to a halt in further studies on D112. We decided to revive investigations on D112 and have further characterized D112-induced cellular toxicity. We identified that in response to D112 treatment, the T-cell leukemia cell line Jurkat showed caspase activation, mitochondrial depolarization, and phosphatidylserine externalization, all of which are hallmarks of apoptosis. Chemical inhibition of caspase enzymatic activity and blockade of the mitochondrial pathway through Bcl-2 expression inhibited D112-induced apoptosis. At lower concentrations, D112 induced growth arrest. To gain insight into the molecular mechanism of D112 induced mitochondrial dysfunction, we analyzed the intracellular localization of D112, and found that D112 associated with mitochondria. Interestingly, in the cell lines that we tested, D112 showed increased toxicity toward transformed versus non-transformed cells. Results from this work identify D112 as a potentially interesting molecule warranting further investigation.

  10. The potential of selected macroalgal species for treatment of AMD at different pH ranges in temperate regions.

    Science.gov (United States)

    Oberholster, Paul J; Cheng, Po-Hsun; Botha, Anna-Maria; Genthe, Bettina

    2014-09-01

    The metal bioaccumulation potential of selected macroalgae species at different pH ranges was study for usage as part of a possible secondary passive acid mine drainage (AMD) treatment technology in algae ponds. Two separate studies were conducted to determine the suitability of macroalgae for passive treatment when metabolic processes in macrophytes and microorganisms in constructed wetlands decrease during winter months. In the field study, the bioconcentration of metals (mg/kg dry weight) measured in the benthic macroalgae mats was in the following order: site 1. Oedogonium crassum Al > Fe > Mn > Zn; site 2. Klebsormidium klebsii, Al > Fe > Mn > Zn; site 3. Microspora tumidula, Fe > Al > Mn > Zn and site 4. M. tumidula, Fe > Mn > Al > Zn. In the laboratory study, cultured macroalgae K. klebsii, O. crassum and M. tumidula isolated from the field sampling sites were exposed to three different pH values (3, 5 and 7), while bioaccumulation of the metals, Al, Fe, Mn and Zn and glutathione S-transferase (GST) activity were measured in the different selected algae species at a constant water temperature of 14 °C. Bioaccumulation of Al was the highest for O. crassum followed by K. klebsii and M. tumidula (p < 0.0001). From the study it was evident that the highest metal bioaccumulation occurred in the macroalgae O. crassum at all three tested pH values under constant low water temperature.

  11. Geochemical characterization of supraglacial debris via in situ and optical remote sensing methods: a case study in Khumbu Himalaya, Nepal

    Directory of Open Access Journals (Sweden)

    K. A. Casey

    2012-01-01

    Full Text Available Surface glacier debris samples and field spectra were collected from the ablation zones of Nepal Himalaya Ngozumpa and Khumbu glaciers in November and December 2009. Geochemical and mineral compositions of supraglacial debris were determined by X-ray diffraction and X-ray fluorescence spectroscopy. This composition data was used as ground truth in evaluating field spectra and satellite supraglacial debris composition and mapping methods. Satellite remote sensing methods for characterizing glacial surface debris include visible to thermal infrared hyper- and multispectral reflectance and emission signature identification, semi-quantitative mineral abundance indicies and spectral image composites. Satellite derived supraglacial debris mineral maps displayed the predominance of layered silicates, hydroxyl-bearing and calcite minerals on Khumbu Himalayan glaciers. Supraglacial mineral maps compared with satellite thermal data revealed correlations between glacier surface composition and glacier surface temperature. Glacier velocity displacement fields and shortwave, thermal infrared false color composites indicated the magnitude of mass flux at glacier confluences. The supraglacial debris mapping methods presented in this study can be used on a broader scale to improve, supplement and potentially reduce errors associated with glacier debris radiative property, composition, areal extent and mass flux quantifications.

  12. Geochemical characterization of supraglacial debris via in situ and optical remote sensing methods: a case study in Khumbu Himalaya, Nepal

    Science.gov (United States)

    Casey, K. A.; Kääb, A.; Benn, D. I.

    2012-01-01

    Surface glacier debris samples and field spectra were collected from the ablation zones of Nepal Himalaya Ngozumpa and Khumbu glaciers in November and December 2009. Geochemical and mineral compositions of supraglacial debris were determined by X-ray diffraction and X-ray fluorescence spectroscopy. This composition data was used as ground truth in evaluating field spectra and satellite supraglacial debris composition and mapping methods. Satellite remote sensing methods for characterizing glacial surface debris include visible to thermal infrared hyper- and multispectral reflectance and emission signature identification, semi-quantitative mineral abundance indicies and spectral image composites. Satellite derived supraglacial debris mineral maps displayed the predominance of layered silicates, hydroxyl-bearing and calcite minerals on Khumbu Himalayan glaciers. Supraglacial mineral maps compared with satellite thermal data revealed correlations between glacier surface composition and glacier surface temperature. Glacier velocity displacement fields and shortwave, thermal infrared false color composites indicated the magnitude of mass flux at glacier confluences. The supraglacial debris mapping methods presented in this study can be used on a broader scale to improve, supplement and potentially reduce errors associated with glacier debris radiative property, composition, areal extent and mass flux quantifications.

  13. Wind characteristic and energy potentialities of some selected sites in the Yemen Arab Republic and the Republic of Egypt

    Energy Technology Data Exchange (ETDEWEB)

    Abu El-Eizz, H.M.; Abu El-Eizz, Z.A. (Zagazig Univ. (EG). Dept. of Physics); Al-Motawakel, M.K. (Sana' s Univ., Sana' a (Yemen Arab Republic). Dept. of Physics)

    1991-01-01

    The wind regimes as observed in four meteorological stations in the Yemen Arab Republic and eight meteorological stations in the Republic of Egypt are presented in the form of velocity and power duration curves as well as in the form of velocity and power frequency curves. Based on the analyzed data, the utilization of wind for power production purposes is promising particularly in the coastal stations of both countries. In the locations considered and allowing for aerodynamic imperfections and mechanical as well as electrical losses, the extracted annual amounts of wind energy (evaluated at a wind system conversion efficiency of 40%) range from 103 to 576 kW h per unit area swept by the rotor blades. The energy potentialities of the considered sites are measured by the wind energy utilization factor and presented in the form of design diagrams which can be used in determining the suitability of the sites for wind energy generation as well as in selecting the technical characteristics of the wind turbines. (author).

  14. Herbal Therapies for Type 2 Diabetes Mellitus: Chemistry, Biology, and Potential Application of Selected Plants and Compounds

    Directory of Open Access Journals (Sweden)

    Cicero L. T. Chang

    2013-01-01

    Full Text Available Diabetes mellitus has been recognized since antiquity. It currently affects as many as 285 million people worldwide and results in heavy personal and national economic burdens. Considerable progress has been made in orthodox antidiabetic drugs. However, new remedies are still in great demand because of the limited efficacy and undesirable side effects of current orthodox drugs. Nature is an extraordinary source of antidiabetic medicines. To date, more than 1200 flowering plants have been claimed to have antidiabetic properties. Among them, one-third have been scientifically studied and documented in around 460 publications. In this review, we select and discuss blood glucose-lowering medicinal herbs that have the ability to modulate one or more of the pathways that regulate insulin resistance, β-cell function, GLP-1 homeostasis, and glucose (reabsorption. Emphasis is placed on phytochemistry, anti-diabetic bioactivities, and likely mechanism(s. Recent progress in the understanding of the biological actions, mechanisms, and therapeutic potential of compounds and extracts of plant origin in type 2 diabetes is summarized. This review provides a source of up-to-date information for further basic and clinical research into herbal therapy for type 2 diabetes. Emerging views on therapeutic strategies for type 2 diabetes are also discussed.

  15. Tectonics, exhumation, and drainage evolution of the eastern Himalaya since 13 Ma from detrital geochemistry and thermochronology, Kameng River Section, Arunachal Pradesh

    NARCIS (Netherlands)

    Chirouze, F.; Huyghe, P.; van der Beek, P.; Chauvel, C.; Chakraborty, T.; Dupont-Nivet, G.; Bernet, M.

    2013-01-01

    The exhumation history of the central Himalaya is well documented, but lateral variations in exhumation remain poorly constrained. In this study, we identify sediment source areas and examine the late Neogene exhumation history of the eastern Himalaya from the synorogenic sedimentary record of its f

  16. A probe into the medicinal potential of Viola canescens – A threatened medicinal plant from Himalaya

    Directory of Open Access Journals (Sweden)

    Sidra Sabir

    2016-07-01

    Full Text Available Viola canescens Wall. ex Roxb. is a perennial herb belonging to family Violaceae, and it is almost cosmopolitan in distribution. This plant is widely used in Ayurveda and Unani medicinal systems for curing various ailments, most commonly for cough and cold. Phytochemical studies releaved that this plant is rich in secondary metabolites. This plant revealed significant antimicrobial, anti-inflamatory, antioxidant, hepatoprotective, laxative, analgesic as well as antitumor activities. Due to all these important pharmacological activities, market demand of Viola canescens is increasing day by day and this plant is facing tremendous over exploitation and becomes a threatened plant according to International Union for Conservation of Nature and Natural Resources. The present review compiles that the ethnobotanical, phytochemical and pharmacological aspects of the plant need to be conserved.

  17. A probe into the medicinal potential ofViola canescens - A threatened medicinal plant from Himalaya

    Institute of Scientific and Technical Information of China (English)

    Sidra Sabir; Ejaz Ahmed; Abida Akram; Naveed Iqbal Raja; Zia-ur-Rehman Mashwani; Sohail; Huma Mehreen Sadaf; Mubashir Hussain; Iqra Riaz; Nabeela Ahmad

    2016-01-01

    Viola canescens Wall. ex Roxb. is a perennial herb belonging to family Violaceae, and it is almost cosmopolitan in distribution. This plant is widely used in Ayurveda and Unani medicinal systems for curing various ailments, most commonly for cough and cold. Phytochemical studies releaved that this plant is rich in secondary metabolites. This plant revealed significant antimicrobial, anti-inflamatory, antioxidant, hepatoprotective, laxative, analgesic as well as antitumor activities. Due to all these important pharmacological activities, market demand of Viola canescens is increasing day by day and this plant is facing tremendous over exploitation and becomes a threatened plant according to International Union for Conservation of Nature and Natural Resources. The present review compiles that the ethnobotanical, phytochemical and pharmacological aspects of the plant need to be conserved.

  18. Identification of sources of polycyclic aromatic hydrocarbons based on concentrations in soils from two sides of the Himalayas between China and Nepal.

    Science.gov (United States)

    Luo, Wei; Gao, Jiajia; Bi, Xiang; Xu, Lan; Guo, Junming; Zhang, Qianggong; Romesh, Kumar Y; Giesy, John P; Kang, Shichang

    2016-05-01

    To understand distribution and sources of polycyclic aromatic hydrocarbons (PAHs) in the Himalayas, 77 soil samples were collected from the northern side of the Himalayas, China (NSHC), and the southern side of the Himalayas, Nepal (SSHN), based on altitude, land use and possible trans-boundary transport of PAHs driven by wind from Nepal to the Tibetan Plateau, China. Soils from the SSHN had mean PAH concentration greater than those from the NSHC. Greater concentrations of PAHs in soils were mainly distributed near main roads and agricultural and urban areas. PAHs with 2-3 rings were the most abundant PAHs in the soils from the Himalayas. Concentrations of volatile PAHs were significantly and positively correlated with altitude. Simulations of trajectories of air masses indicated that distributions of soil PAH concentrations were associated with the cyclic patterns of the monsoon. PAH emissions from traffic and combustion of biomass or coal greatly contributed to concentrations of PAHs in soils from the Himalayas.

  19. Comparative assessment of spatiotemporal snow cover changes and hydrological behavior of the Gilgit, Astore and Hunza River basins (Hindukush-Karakoram-Himalaya region, Pakistan)

    Science.gov (United States)

    Tahir, Adnan Ahmad; Adamowski, Jan Franklin; Chevallier, Pierre; Haq, Ayaz Ul; Terzago, Silvia

    2016-03-01

    The Upper Indus Basin (UIB), situated in the Himalaya-Karakoram-Hindukush (HKH) mountain ranges, is the major contributor to the supply of water for irrigation in Pakistan. Improved management of downstream water resources requires studying and comparing spatiotemporal changes in the snow cover and hydrological behavior of the river basins located in the HKH region. This study explored in detail the recent changes that have occurred in the Gilgit River basin (12,656 km2; western sub-basin of UIB), which is characterized by a mean catchment elevation of 4250 m above sea level (m ASL). The basin's snow cover was monitored through the snow products provided by the MODIS satellite sensor, while analysis of its hydrological regime was supported by hydrological and climatic data recorded at different altitudes. The Gilgit basin findings were compared to those previously obtained for the lower-altitude Astore basin (mean catchment elevation = 4100 m ASL) and the higher-altitude Hunza basin (mean catchment elevation = 4650 m ASL). These three catchments were selected because of their different glacier coverage, contrasting area distribution at high altitudes and significant impact on the Upper Indus River flow. Almost 7, 5 and 33 % of the area of the Gilgit, Astore and Hunza basins, respectively, are situated above 5000 m ASL, and approximately 8, 6 and 25 %, respectively, are covered by glaciers. The UIB region was found to follow a stable or slightly increasing trend in snow coverage and had a discharge dominated by snow and glacier melt in its western (Hindukush-Karakoram), southern (Western-Himalaya) and northern (Central-Karakoram) sub-basins.

  20. Comparative assessment of spatiotemporal snow cover changes and hydrological behavior of the Gilgit, Astore and Hunza River basins (Hindukush-Karakoram-Himalaya region, Pakistan )

    Science.gov (United States)

    Tahir, Adnan Ahmad; Adamowski, Jan Franklin; Chevallier, Pierre; Haq, Ayaz Ul; Terzago, Silvia

    2016-12-01

    The Upper Indus Basin (UIB), situated in the Himalaya-Karakoram-Hindukush (HKH) mountain ranges, is the major contributor to the supply of water for irrigation in Pakistan. Improved management of downstream water resources requires studying and comparing spatiotemporal changes in the snow cover and hydrological behavior of the river basins located in the HKH region. This study explored in detail the recent changes that have occurred in the Gilgit River basin (12,656 km2; western sub-basin of UIB), which is characterized by a mean catchment elevation of 4250 m above sea level (m ASL). The basin's snow cover was monitored through the snow products provided by the MODIS satellite sensor, while analysis of its hydrological regime was supported by hydrological and climatic data recorded at different altitudes. The Gilgit basin findings were compared to those previously obtained for the lower-altitude Astore basin (mean catchment elevation = 4100 m ASL) and the higher-altitude Hunza basin (mean catchment elevation = 4650 m ASL). These three catchments were selected because of their different glacier coverage, contrasting area distribution at high altitudes and significant impact on the Upper Indus River flow. Almost 7, 5 and 33 % of the area of the Gilgit, Astore and Hunza basins, respectively, are situated above 5000 m ASL, and approximately 8, 6 and 25 %, respectively, are covered by glaciers. The UIB region was found to follow a stable or slightly increasing trend in snow coverage and had a discharge dominated by snow and glacier melt in its western (Hindukush-Karakoram), southern (Western-Himalaya) and northern (Central-Karakoram) sub-basins.

  1. Potential tumor-tropic effect of genetically engineered stem cells expressing suicide enzymes to selectively target invasive cancer in animal models.

    Science.gov (United States)

    Kim, Seung U; Jeung, Eui-Bae; Kim, Yun-Bae; Cho, Myung-Haing; Choi, Kyung-Chul

    2011-04-01

    Stem cells have recently received a great deal of attention for their clinical and therapeutic potential to treat human disease and disorders. For instance, neural stem cells expressing a suicide gene which can concert prodrugs to their active metabolites may have great tropic and therapeutic potential for brain tumors, i.e., medulloblastoma and glioma. We are currently interested in therapeutic potential of these genetically engineered stem cells (GESTECs) to selectively target invasive tumors, i.e. ovarian, endometrial, breast, and lung cancer which can have a great impact on human and animal health. Thus, in this review we summarize the therapeutic potential of GESTEC, developed by us, and the putative mechanism(s) underlying their therapeutic and tropic potential in expressing suicide genes which can convert prodrugs to their active metabolites and in selectively targeting invasive tumors.

  2. Selection of lactic acid bacteria from Brazilian kefir grains for potential use as starter or probiotic cultures.

    Science.gov (United States)

    Zanirati, Débora Ferreira; Abatemarco, Mário; Sandes, Sávio Henrique de Cicco; Nicoli, Jacques Robert; Nunes, Álvaro Cantini; Neumann, Elisabeth

    2015-04-01

    Brazilian kefir is a homemade fermented beverage that is obtained by incubating milk or a brown sugar solution with kefir grains that contribute their different microbiological compositions. It is highly important to isolate and characterize microorganisms from Brazilian kefir grains to obtain starter cultures for the industrial production of a standardized commercial kefir. Thus, the present study aimed to isolate lactic acid bacteria from eight kefir grains that were propagated in milk or sugar solutions from five different locations in Brazil and to select Lactobacillus isolates based on desirable in vitro probiotic properties. One hundred eight isolates from both substrates were identified by amplified ribosomal DNA restriction analysis and/or 16S rRNA gene sequencing and were determined to belong to the following 11 species from the genera: Lactococcus, Leuconostoc, Lactobacillus (L.), and Oenococcus. Leuconostoc mesenteroides, Lactobacillus kefiri, and Lactobacillus kefiranofaciens were isolated only from milk grains, whereas Lactobacillus perolens, Lactobacillus parafarraginis, Lactobacillus diolivorans, and Oenococcus oeni were isolated exclusively from sugar water grains. When the microbial compositions of four kefir grains were evaluated with culture-independent analyses, L. kefiranofaciens was observed to predominant in milk grains, whereas Lactobacillus hilgardii was most abundant in sugar water kefir. Unfortunately, L. hilgardii was not isolated from any grain, although this bacteria was detected with a culture-independent methodology. Fifty-two isolated Lactobacilli were tested for gastric juice and bile salt tolerance, antagonism against pathogens, antimicrobial resistance, and surface hydrophobicity. Three Lactobacillus strains (L. kefiranofaciens 8U, L. diolivorans 1Z, and Lactobacillus casei 17U) could be classified as potential probiotics. In conclusion, several lactic acid bacteria that could be used in combination with yeasts as starter

  3. Spatiotemporal variation in exhumation of the Crystallines in the NW-Himalaya, India: Constraints from fission track dating analysis

    Science.gov (United States)

    Patel, R. C.; Adlakha, Vikas; Lal, Nand; Singh, Paramjeet; Kumar, Y.

    2011-05-01

    During Himalayan orogeny, coeval thrusting along the Main Central/Munsiari Thrust (MCT/MT) and extension along the South Tibetan-Detachment System (STDS) are widely responsible for rapid exhumation of the Higher Himalayan Crystalline (HHC) zone. Apatite and zircon fission-track data along the Kaliganga and Darma valleys in the Kumaon Himalaya serve to document the shallow bedrock exhumation history of the HHC. Taking into account sample location within the HHC with respect to the MCT/MT, the apatite fission track (AFT) data-sets along the Darma (1.0 ± 0.1 to 2.8 ± 0.3 Ma) and Kaliganga (1.4 ± 0.2 to 2.4 ± 0.3 Ma) which are sharing same structural setting and rock types and being separated by 40 km, show very similar patterns of exhumation histories since Plio-Quaternary in the Kumaon Himalaya. Data sets along Darma and Kaliganga are very similar to data set of adjacent traverse (50 km away) along the Goriganga valley studied by Patel and Carter (2009). Whole data sets within the HHC in Kumaon Himalaya provide clear evidence for Plio-Quaternary tectonic activity along the Vaikrita Thrust (VT). Precipitation in this region exerts a strong influence on erosional surface processes. Fluvial erosional unloading along the Himalaya is focused on the high mountainous region of the HHC, where the orographic barrier forces out the maximum percentage of annual rainfall. FT cooling ages reveal coincidence between rapid erosion and exhumation that is focused in a ~ 25-30 km wide sector of the HHC, rather than covering the entire orogen. Similarity of AFT age pattern and exhumation rates along all three major traverses (Goriganga, Darma and Kaliganga) indicates that the region has been experiencing constant rate of crustal uplift and erosion since long time. Comparison of fission track ages from the Kumaon Himalaya with other segments of the NW-Himalaya shows spatiotemporal variation in exhumation. It is described due to the development of local structures such as dome

  4. New Mycomya species from the Himalayas (Diptera, Mycetophilidae): 2. Subgenera Calomycomya, Cymomya, Neomycomya and Pavomya subg. n.

    Science.gov (United States)

    Väisänen, Rauno

    2013-01-01

    Myconya Rondani specimens from the Himalayas, mostly Nepal and Myanmar, are revised. Pavoniya subg. n. is described. Altogether nine species from the subgenera Calomycoinya, Cymnoniya, Neoinycoinya and Pavomya subg. n. are recorded from the Himalayas and Indian subcontinent. The paper includes a key to the subgenera of Myconiya and the Himalayan species of Mycomya of the four subgenera. The following eight new species are described: M. aonyx, M. cuon, M. kainbaitiensis, M. marmota, M. paguina, M. panthera, M. ratufa and M. wah. Mycomyafiubriata (Meigen) is recorded from Myanmar.

  5. Recent temperature trends at mountain stations on the southern slope of the central Himalayas

    Indian Academy of Sciences (India)

    Dambaru Ballab Kattel; Tandong Yao

    2013-02-01

    Insufficient long-term in situ observations and complex topographic conditions pose major problems in quantifying the magnitude of climatic trends in mountainous regions such as Nepal. Presented here is three decades (1980–2009) of data on annual maximum, minimum and average temperature trends from 13 mountain stations on the southern slope of the central Himalayas. The stations are located at elevations between 1304 and 2566 m above sea level and with varied topography. Spatial analyses of the average temperature trend show warming in most of the stations. The magnitude of warming is higher for maximum temperatures, while minimum temperatures exhibit larger variability such as positive, negative or no change. These results are consistent with patterns reported in some parts of the Indian subcontinent and Upper Indus Basin, but different from conditions on the Tibetan Plateau (China), where the warming of minimum temperatures is more prominent than that of the maximum temperatures. From the temporal variations, a dramatic increase in temperature is observed in the latest decade, particularly in the average and maximum temperatures. The results from the cumulative sum chart analyses suggest that the thermal regime shifted in 1997. The dramatic enhancement of average temperature in the last decade is strongly consistent with the result of contemporary studies of the surrounding regions, where warming is attributed to an increase in anthropogenic greenhouse gases. However, as in the western Himalayas and the Upper Indus Basin, the mountain stations on the southern slope of the central Himalayas show variability in temperature trends, particularly for the minimum temperature. This inhomogeneous trend is likely ascribed to the differences in topography and microclimatic regime of the observed stations.

  6. Uncertainties in the Shuttle Radar Topography Mission (SRTM) Heights: Insights from the Indian Himalaya and Peninsula

    Science.gov (United States)

    Mukul, Manas; Srivastava, Vinee; Jade, Sridevi; Mukul, Malay

    2017-02-01

    The Shuttle Radar Topography Mission (SRTM) Digital Terrain Elevation Data (DTED) are used with the consensus view that it has a minimum vertical accuracy of 16 m absolute error at 90% confidence (Root Mean Square Error (RMSE) of 9.73 m) world-wide. However, vertical accuracy of the data decreases with increase in slope and elevation due to presence of large outliers and voids. Therefore, studies using SRTM data “as is”, especially in regions like the Himalaya, are not statistically meaningful. New data from ~200 high-precision static Global Position System (GPS) Independent Check Points (ICPs) in the Himalaya and Peninsular India indicate that only 1-arc X-Band data are usable “as is” in the Himalaya as it has height accuracy of 9.18 m (RMSE). In contrast, recently released (2014–2015) “as-is” 1-arc and widely used 3-arc C-Band data have a height accuracy of RMSE 23.53 m and 47.24 m and need to be corrected before use. Outlier and void filtering improves the height accuracy to RMSE 8 m, 10.14 m, 14.38 m for 1-arc X and C-Band and 3-arc C-Band data respectively. Our study indicates that the C-Band 90 m and 30 m DEMs are well-aligned and without any significant horizontal offset implying that area and length computations using both the datasets have identical values.

  7. Aerosol chemistry over a high altitude station at northeastern Himalayas, India.

    Directory of Open Access Journals (Sweden)

    Abhijit Chatterjee

    Full Text Available BACKGROUND: There is an urgent need for an improved understanding of the sources, distributions and properties of atmospheric aerosol in order to control the atmospheric pollution over northeastern Himalayas where rising anthropogenic interferences from rapid urbanization and development is becoming an increasing concern. METHODOLOGY/PRINCIPAL FINDINGS: An extensive aerosol sampling program was conducted in Darjeeling (altitude approximately 2200 meter above sea level (masl, latitude 27 degrees 01'N and longitude 88 degrees 15'E, a high altitude station in northeastern Himalayas, during January-December 2005. Samples were collected using a respirable dust sampler and a fine dust sampler simultaneously. Ion chromatograph was used to analyze the water soluble ionic species of aerosol. The average concentrations of fine and coarse mode aerosol were found to be 29.5+/-20.8 microg m(-3 and 19.6+/-11.1 microg m(-3 respectively. Fine mode aerosol dominated during dry seasons and coarse mode aerosol dominated during monsoon. Nitrate existed as NH(4NO(3 in fine mode aerosol during winter and as NaNO(3 in coarse mode aerosol during monsoon. Gas phase photochemical oxidation of SO(2 during premonsoon and aqueous phase oxidation during winter and postmonsoon were the major pathways for the formation of SO(4(2- in the atmosphere. Long range transport of dust aerosol from arid regions of western India was observed during premonsoon. The acidity of fine mode aerosol was higher in dry seasons compared to monsoon whereas the coarse mode acidity was higher in monsoon compared to dry seasons. Biomass burning, vehicular emissions and dust particles were the major types of aerosol from local and continental regions whereas sea salt particles were the major types of aerosol from marine source regions. CONCLUSIONS/SIGNIFICANCE: The year-long data presented in this paper provide substantial improvements to the heretofore poor knowledge regarding aerosol chemistry over

  8. Topography and Radiative Forcing Patterns on Glaciers in the Karakoram Himalaya

    Science.gov (United States)

    Dobreva, I. D.; Bishop, M. P.; Liu, J. C.; Liang, D.

    2015-12-01

    Glaciers in the western Himalaya exhibit significant spatial variations in morphology and dynamics. Climate, topography and debris cover variations are thought to significantly affect glacier fluctuations and glacier sensitivity to climate change, although the role of topography and radiative forcing have not been adequately characterized and related to glacier fluctuations and dynamics. Consequently, we examined the glaciers in the Karakoram Himalaya, as they exhibit high spatial variability in glacier fluctuation rates and ice dynamics including flow velocity and surging. Specifically, we wanted to examine the relationships between these glacier characteristics and temporal patterns of surface irradiance over the ablation season. To accomplish this, we developed and used a rigorous GIS-based solar radiative transfer model that accounts for the direct and diffuse-skylight irradiance components. The model accounts for multiple topographic effects on the magnitude of irradiance reaching glacier surfaces. We specifically used the ASTER GDEM digital elevation model for irradiance simulations. We then examined temporal patterns of irradiance at the grid-cell level to identify the dominant patterns that were used to train a 3-layer artificial neural network. Our results demonstrate that there are unique spatial and temporal patterns associated with downwasting and surging glaciers, and that these patterns partially account for the spatial distribution of advancing and retreating glaciers. Lower-altitude terminus regions of surging glaciers exhibited relatively low surface irradiance values that decreased in magnitude with time, demonstrating that high-velocity surging glaciers facilitate relief production and exhibit steeper surface irradiance gradients with altitude. Collectively, these results demonstrate the important role that local and regional topography play in governing climate-glacier dynamics in the Himalaya.

  9. Vulnerability assessment of Glacial Lake Outburst Floods using Remote Sensing and GIS in North Sikkim (India), Eastern Himalaya

    Science.gov (United States)

    Aggarwal, Suruchi; Probha Devi, Juna; Thakur, Praveen Kumar; Rai, Suresh Chand

    2016-04-01

    Glacial lake outburst floods (GLOFs) occur when glacier melt water dammed by a moraine is released in short time. Such floods may lead to disastrous events posing, therefore, a huge threat to human lives and infrastructure. A devastating GLOF in Uttarakhand, India, on 17 July 2013 has led to the loss of all villages in a stretch of 18 km downstream the lake and the loss of more than 5000 lives. The present study evaluates all 16 glacial lakes (with an area >0.1 km²) in the Thangu valley, northern Sikkim (India), eastern Himalaya, with respect to potential threats for the downstream areas. The hazard criteria for the study include slope, aspect and distance of the respective parent glacier, change in the lake area, dam characteristics and lake depth. For the most hazardous lakes, the socio-economic conditions in the downstream areas (settlements and infrastructure) are analysed regarding the impact of potential GLOFs. For the vulnerability analysis, we used various satellite products including LANDSAT, RESOUCESAT-1 and 2, RISAT-1 imageries and ASTER GDEM covering the period from 1977 to 2014. For lake mapping, we applied the Normalized Difference Vegetation Index (NDVI) and the Normalized Difference Snow Index (NDSI). A Land Use Land Cover (LULC) map of the study area showing in-situ observations is serving as driving factor for the vulnerability analysis. The results of the study show that almost all evaluated glacial lakes were expanding during the study period (1977-2014). Combining the hazard criteria for the lakes, 5 of the 16 studied glacial lakes are identified as highly hazardous. In the downstream area, there are two villages with 200 inhabitants and an army camp within the zone of highest vulnerability. The identified vulnerability zones may be used by the local authorities to take caution of the threatened villages and infrastructure and for risk analysis for planned future hydropower plants.

  10. Water soluble ions in aerosols (TSP) : Characteristics, sources and seasonal variation over the central Himalayas, Nepal

    Science.gov (United States)

    Tripathee, Lekhendra; Kang, Shichang; Zhang, Qianggong; Rupakheti, Dipesh

    2016-04-01

    Atmspheric pollutants transported from South Asia could have adverse impact on the Himalayan ecosystems. Investigation of aerosol chemistry in the Himalayan region in Nepal has been limited on a temporal and spatial scale to date. Therefore, the water-soluble ionic composition of aerosol using TSP sampler was investigated for a year period from April 2013 to March 2014 at four sites Bode, Dhunche, Lumbini and Jomsom characterized as an urban, rural, semi-urban and remote sites in Nepal. During the study period, the highest concentration of major cation was Ca2+ with an average concentration of 8.91, 2.17, 7.85 and 6.42 μg m-3 and the highest concentration of major anion was SO42- with an average of 10.96, 4.06, 6.85 and 3.30 μg m-3 at Bode, Dhunche, Lumbini and Jomsom respectively. The soluble ions showed the decrease in concentrations from urban to the rural site. Correlations and PCA analysis suggested that that SO42-, NO3- and NH4+ were derived from the anthropogenic sources where as the Ca2+ and Mg2+ were from crustal sources. Our results also suggest that the largest acid neutralizing agent at our sampling sites in the central Himalayas are Ca2+ followed by NH4+. Seasonal variations of soluble ions in aerosols showed higher concentrations during pre-monsoon and winter (dry-periods) due to limited precipitation amount and lower concentrations during the monsoon which can be explained by the dilution effect, higher the precipitation lower the concentration. K+ which is regarded as the tracer of biomss burning had a significant peaks during pre-monsoon season when the forest fires are active around the regions. In general, the results of this study suggests that the atmospheric chemistry is influenced by natural and anthropogenic sources. Thus, soluble ionic concentrations in aerosols from central Himalayas, Nepal can provide a useful database to assess atmospheric environment and its impacts on human health and ecosystem in the southern side of central

  11. The long-range transport of atmospheric aerosols from South Asia to Himalayas

    Science.gov (United States)

    Cong, Zhiyuan; Kang, Shichang; Kawamura, Kimitaka

    2016-04-01

    High levels of carbonaceous aerosol exist over South Asia, the area adjacent to the Himalayas and Tibetan Plateau. Little is known about if they can be transported across the Himalayas, and as far inland as the Tibetan Plateau. To resolve such scientific questions, aerosol samples were collected weekly from August 2009 to July 2010 at Qomolangma (Mt. Everest) Station for Atmospheric and Environmental Observation and Research(QOMS, 4276 m a.s.l.). In the laboratory, major ions, elemental carbon, organic carbon, levoglucosan, water-soluble organic carbon, and organic acids were analyzed. The concentration levels of OC and EC at QOMS are comparable to those at high-elevation sites on the southern slopes of the Himalayas (Langtang and NCO-P), but 3 to 6 times lower than those at Manora Peak, India, and Godavari, Nepal. Sulfate was the most abundant anion species followed by nitrate. The dust loading, represented by Ca2+ concentration, was relatively constant throughout the year. OC, EC and other ionic species (NH+4 , K+, NO- and SO2-) exhibited a pronounced peak in the pre-monsoon period and a minimum in the monsoon season, being similar to the seasonal trends of aerosol compo-sition reported previously from the southern slope of the Himalayas. The strong correlation of OC and EC in QOMS aerosols with K+ and levoglucosan indicates that they mainly originated from biomass burning. Molecular distributions of dicarboxylic acids and related compounds (malonic acid/ succinic acid, maleic acid/fumaric acid) further support this finding. The fire spots observed by MODIS and backward air-mass trajectories further demonstrate that in pre-monsoon season, agricultural and forest fires in northern India and Nepal were most likely sources of carbonaceous aerosol at QOMS. In addition to large-scale atmospheric circulation, the unique mountain/valley breeze system can also have an important effect on air-pollutant transport.With the consideration of the darkening force of

  12. Relation between soil-gas radon variation and different lithotectonic units, Garhwal Himalaya, India

    Energy Technology Data Exchange (ETDEWEB)

    Choubey, Vinay M.; Bist, K.S.; Saini, N.K. [Wadia Institute of Himalayan Geology, Dehra Dun (India); Ramola, R.C. [Physics Department, H.N.B. Garhwal University campus, Tehri Garhwal (India)

    1999-11-01

    Measurements of radon concentration and uranium content in soil and rocks were made in the regions of the Alaknanda and Bhagirathi valleys in the Garhwal Himalaya by using radon emanometry and X-ray fluorescence method, respectively. The data were collected from different lithotectonic units along and across the various regional thrust planes, faults, shears, etc. The observed values were then correlated with the geological formations and structure of the area. Radon concentrations were found to be controlled by lithology, structure and associated uranium mineralization. A positive linear correlation was also observed between soil-gas radon and in situ uranium in the area.

  13. Recent approach to Buchia biostratigraphy from the Tethyan Himalaya area,China

    Institute of Scientific and Technical Information of China (English)

    Bai Zhiqiang; Xia Zunyi

    2006-01-01

    Recent collections from six sections in Lanongla area,Tethyan Himalaya allow the establishment of four buchia assembles.In ascending they are Buchia-Buchia spitiensis,Buchia masquensis-Buchia rugasa,Buchia blanfordiana,Buchia piochii and Buchia subokensis assemblages.These Buchia assemblages first demonstrate that not only the Upper Jurassic strata but also the highest Buchia assemblage-Buchia subokensis,which appeared in Lower Cretaceous strata all over the world are present in Lanongla area.This first records the highest Buchia assemblage in Lanongla area.

  14. An Investigation of Climate Change Impact on Snow/Ice Melts Runoff in Himalayas

    Science.gov (United States)

    Selvan, M. T.; Ahmad, S. S.

    2005-12-01

    Glacial density varies across Himalayas, maximum in the Sutlej and Tista basin and moderate in Jhelum and Bhagirathi basin, while least density is in Arunachal Pradesh basin. Most of the glaciers are simple type, but some glaciers are bigger in size and composite in nature. The impact of global warming is perhaps already upon the Himalayas. They are located so near the tropic of cancer that they receive more heat than it commonly reaches Temperate and Arctic glaciers. In all these areas the orographic snowline is often a little higher than regional snowline. In the Himalayas the main source of moisture which feeds the glaciers comes from three sources as Southern monsoon, Northwestern disturbances and Local convection currents. The snowline is also lower on the northern slopes than on the southern slopes. According to the climatologists, alpine glaciers, such as those in the Himalaya are particularly sensitive indicators of climate change and the trend is expected to continue this century. Present study made by the availability of GIS, Image Processing and Digital Data Sets have made the task of runoff modeling easier on the regional and local scenario. For mapping the snow-cover on local level with high resolution remote sensing data (ASTER, LANDSAT and IRS) been used, for regional level, EOS and MODIS used, which provides good images with sufficient temporal scale. Investigation shows that spatial distributions of survival index based on relief area gradient and elongation index has least climate sensitivity of the glaciers situated in the Bhagirathi basin in Ganga headwater. In a high mountain environment the influence of certain topographic variables varying greatly. Elevation is one of the variables that have been identified as having a positive effect on snow depth and other factors those influence snow accumulation and the snowpack also computed for relational study. The variations in snow cover have a major influence on regional and continental weather

  15. New data on Apteroloma (Coleoptera: Agyrtidae) of central Asia and the Himalayas with a new synonymy.

    Science.gov (United States)

    Růžička, Jan; Latella, Leonardo; Schawaller, Wolfgang

    2014-06-19

    The distribution of Apteroloma anglorossicum (Semenov, 1890), A. harmandi (Portevin, 1903) and A. sillemi Jeannel, 1935 in central Asia and along the Himalayas is summarized, and the collecting circumstances and ecology of all three species from Gilgit District, Pakistan are described in detail. Revised diagnoses of all three species are provided, habitus and important morphological structures are illustrated, and available types have been examined. Apteroloma jankovskii Semenov and Znojko in Semenov, 1932 is confirmed as junior subjective synonym of A. anglorossicum. Apteroloma heinzi Schawaller, 1991 is newly treated as a junior subjective synonym of A. harmandi.

  16. Late Miocene-Pleistocene evolution of India-Eurasia convergence partitioning between the Bhutan Himalaya and the Shillong Plateau: New evidences from foreland basin deposits along the Dungsam Chu section, eastern Bhutan

    Science.gov (United States)

    Coutand, Isabelle; Barrier, Laurie; Govin, Gwladys; Grujic, Djordje; Hoorn, Carina; Dupont-Nivet, Guillaume; Najman, Yani

    2016-12-01

    The Shillong Plateau is a unique basement-cored uplift in the foreland of the eastern Himalaya that accommodates part of the India-Eurasia convergence since the late Miocene. It was uplifted in the late Pliocene to 1600 m, potentially inducing regional climatic perturbations by orographically condensing part of the Indian Summer Monsoon (ISM) precipitations along its southern flank. As such, the eastern Himalaya-Shillong Plateau-ISM is suited to investigate effects of tectonics, climate, and erosion in a mountain range-broken foreland system. This study focuses on a 2200 m thick sedimentary section of the Siwalik Group strategically located in the lee of the Shillong Plateau along the Dungsam Chu at the front of the eastern Bhutan Himalaya. We have performed magnetostratigraphy constrained by vitrinite reflectance and detrital apatite fission track dating, combined with sedimentological and palynological analyses. We show that (1) the section was deposited between 7 and 1 Ma in a marginal marine deltaic transitioning into continental environment after 5 Ma, (2) depositional environments and paleoclimate were humid with no major change during the depositional period indicating that the orographic effect of the Shillong Plateau had an unexpected limited impact on the paleoclimate of the Bhutanese foothills, and (3) the diminution of the flexural subsidence in the basin and/or of the detrital input from the range is attributable to a slowdown of the displacement rates along the Main Boundary Thrust in eastern Bhutan during the latest Miocene-Pleistocene, in response to increasing partitioning of the India-Eurasia convergence into the active faults bounding the Shillong Plateau.

  17. The Collision Timing and Subsequent Deformation Phases in the Western Himalaya during the India-Eurasia Collision

    Science.gov (United States)

    Jagoutz, O.; Upadhyay, R.; Bouilhol, P.; Van Buer, N. J.; Hanchar, J. M.

    2012-12-01

    The western Himalaya differ from the central and eastern Himalaya due to the presence of the Kohistan-Ladakh paleo Island arc (KLA) that separates India from the former Eurasian margin (e.g. Karakoram). The KLA is separated from India by the Indus suture zone in the south, and in the north by the Shyok suture zone from the Karakorum. In an effort to understand the complicated collisional history in the western Himalaya we mapped ~8000 km2 in the western Himalaya in India over the last 4 years, focusing in detail on the intersection of the Shyok suture zone and the Karakoram fault. These results in combination with our previous work and published results from the western Himalaya in Pakistan, and U-Pb Zircon geochronology allows us to constrain the collisional history related to the India-Eurasia collision of this poorly studied region of the Himalayas. Our mapping indicate that the western Himalaya in India is dominated by four major fault zones: (1) the north dipping Indus suture, previously dated at 50 Ma; (2) the Shyok suture an originally south dipping fault zone of essentially unknown age; (3) a north dipping thrusts and reverse fault system likely the equivalent of the Karakoram thrust system described from northern Pakistan; and finally (4) the dextral Karakorum strike-slip fault. The continental Saltoro Molasse composed of conglomerate and sandstones is generally spatially associated in our mapping area with the Shyok suture zone and likely the western equivalent of the Purit formation described in Pakistan. The deposition of the Saltoro molasses postdated the formation of the Shyok suture zones, as serpentinized ultramafic conglomerate clasts are common in the molasse and are likely derived from the near-by ultramafics of the Shyok suture zone. However, both the Shyok suture and the Saltoro molasse are affected by the thrusting along the Karakoram thrust system and the deformation associated with movement of the Karakoram fault. These relative age

  18. Productivity status of traditional agrisilviculture system on northern and southern aspects in mid-hill situation of Garhwal Himalaya, India

    Institute of Scientific and Technical Information of China (English)

    Arvind Bijalwan; Chandra Mohan Sharma; V. K. Sah

    2009-01-01

    The productivity of traditional agrisilviculture system (agricultural crops + trees) was investigated in the northern and southern aspects of mid-hill situation in Garhwal Himalaya, Uttarakhand, India during the 2004-2006. A total of 19 tree species were studied in both northern and southern aspects, out of which 17 tree species were selected in northern aspect and 12 tree species in southern aspect for phytosociological characteristic analysis of trees in agrisilvicultural system. The most dominant tree species are Grewia optiva, Celtis australis and Melia azedarach and successively grown under traditional agrisilviculture system. The results show that the annual productivity of all tree species was 3775 kg·ha-1·a-1 in northern aspect (site-N) and 3101 kg·ha-1·a-1 in southern aspect (site-S). G. Optiva had the highest productivity in both site-N and site-S among the tree species, followed by M. Azedarach, Quercus leucotrichophora and C. Australis. The dominant agricultural crops were Eleusine coracana in summer cereals, Phaseolus vulgaris in summer pulses-oilseeds and Triticum aestivum in the winter season in the area. The average biological productivity of agricultural crops in northern aspect was about 16% higher than that in southern aspect under traditional agrisilviculture system. The sole agricultural crop productivity (without trees) in northern aspect was also higher than that in southern aspect. An obvious difference in annual productivity of trees and agriculture crops was observed between northern aspect and southern aspect. The overall productivity in traditional agrisilviculture system (crop + tree) was 24% (in northern aspect) and 21% (in southern aspect) higher than that in sole cropping system.

  19. Impact of Different Land Use Management on Soil Enzyme Activities and Bacterial Genetic Fingerprints of North-Western Himalayas

    Directory of Open Access Journals (Sweden)

    Raj Deo Singh

    2014-12-01

    Full Text Available Land uses has significant impact on soil biological properties that incessantly intimates the soil quality change and are assessed by soil microbial and biochemical indicators, as they are highly sensitive to change in environment. The purpose of this study was to investigate the impact of land use on soil enzyme activities and gene diversity in selected location of Northwestern Himalayas, India. Nine different land use system of similar soil type at depth 0-15 cm were analyzed for soil enzymes (Dehydrogenase, Acid Phosphatase, Alkaline Phosphatase, Nitrate Reductase, Arylsulphatase, and Phytase and genetic fingerprints (Randomly Amplified Polymorphic DNA analysis. The land use systems investigated are Oak (Quercus incana, Deodar (Cedrus deodara, Pine (Pinus roxburghii trees, Apple orchids and crop based systems in uplands and valleys. All the soil enzymes were significantly higher in forest ecosystem followed by organic farm and conventional maize-wheat farm soil. The principal component analysis (PCA of nine different land use systems based on soil enzymes shows significant variation in data and all the long-term agricultural lands were segregated together. However maize-wheat and organic farm are group together in the PCA plot. Hierarchical clustering by wards method of soil enzymes clusters the deodar forest soil, oak forest soil and organic farming in one cluster and segregates remaining land use system in another. RAPD analysis showed high polymorphism between samples and similarity indexing using unweighted pair-group method with arithmetic averages resulted in four clusters. Land use showed significantly negative impact on soil enzymes and genetic fingerprints in long-term agricultural lands as compared to natural forest ecosystem and organic farming as reveal by RAPD assisted marker.

  20. Bone ingrowth potential of electron beam and selective laser melting produced trabecular-like implant surfaces with and without a biomimetic coating

    NARCIS (Netherlands)

    Biemond, J.E.; Hannink, G.J.; Verdonschot, N.J.; Buma, P.

    2013-01-01

    The bone ingrowth potential of trabecular-like implant surfaces produced by either selective laser melting (SLM) or electron beam melting (EBM), with or without a biomimetic calciumphosphate coating, was examined in goats. For histological analysis and histomorphometry of bone ingrowth depth and bon

  1. Catalytic Destruction of a Surrogate Organic Hazardous Air Pollutant as a Potential Co-benefit for Coal-fired Selective Catalyst Reduction Systems

    Science.gov (United States)

    Catalytic destruction of benzene (C6H6), a surrogate for organic hazardous air pollutants (HAPs) produced from coal combustion, was investigated using a commercial selective catalytic reduction (SCR) catalyst for evaluating the potential co-benefit of the SCR technology for reduc...

  2. Event-Related Potentials (ERPs) in Second Language Research: A Brief Introduction to the Technique, a Selected Review, and an Invitation to Reconsider Critical Periods in L2

    Science.gov (United States)

    Steinhauer, Karsten

    2014-01-01

    This article provides a selective overview of recent event-related brain potential (ERP) studies in L2 morpho-syntax, demonstrating that the ERP evidence supporting the critical period hypothesis (CPH) may be less compelling than previously thought. The article starts with a general introduction to ERP methodology and language-related ERP profiles…

  3. Efficient attentional selection predicts distractor devaluation: event-related potential evidence for a direct link between attention and emotion.

    Science.gov (United States)

    Kiss, Monika; Goolsby, Brian A; Raymond, Jane E; Shapiro, Kimron L; Silvert, Laetitia; Nobre, Anna C; Fragopanagos, Nickolaos; Taylor, John G; Eimer, Martin

    2007-08-01

    Links between attention and emotion were investigated by obtaining electrophysiological measures of attentional selectivity together with behavioral measures of affective evaluation. Participants were asked to rate faces that had just been presented as targets or distractors in a visual search task. Distractors were rated as less trustworthy than targets. To study the association between the efficiency of selective attention during visual search and subsequent emotional responses, the N2pc component was quantified as a function of evaluative judgments. Evaluation of distractor faces (but not target faces) covaried with selective attention. On trials where distractors were later judged negatively, the N2pc emerged earlier, demonstrating that attention was strongly biased toward target events, and distractors were effectively inhibited. When previous distractors were judged positively, the N2pc was delayed, indicating unfocused attention to the target and less distractor suppression. Variations in attentional selectivity across trials can predict subsequent emotional responses, strongly suggesting that attention is closely associated with subsequent affective evaluation.

  4. Selected constants oxydo-reduction potentials tables of constants and numerical data affiliated to the International Union of Pure and Applied Chemistry, v.8

    CERN Document Server

    Charlot, G

    1958-01-01

    Selected Constants: Oxydo-Reduction Potentials contains Tables of the most probable value of the normal oxidation-reduction potential, or of the formal or apparent potential, of a given oxidation-reduction system. This book is prepared under the sponsorship of the Commission on Electrochemical Data of the Section of Analytical Chemistry of the International Union of Pure and Applied Chemistry. It is included in a general program of the Section of Analytical Chemistry. Entry items are classified in alphabetical order. This book will be of value to specialized and non-specialized chemists, teach

  5. High altitude dives from 7000 to 14,200 feet in the Himalayas.

    Science.gov (United States)

    Sahni, T K; John, M J; Dhall, A; Chatterjee, A K

    1991-07-01

    Indian Navy divers carried out no-decompression dives at altitudes of 7000 to 14,200 ft (2134-4328 m) in the Nilgiris and Himalayas from May to July 1988. Seventy-eight dives on air and 22 dives on oxygen were carried out at various altitudes. The final dives were at Lake Pangong Tso (4328 m) in Ladakh, Himalayas, to a maximum of 140 feet of sea water (fsw) [42.6 meters of sea water (msw)] equivalent ocean depth in minimum water temperature of 2 degrees C. Oxygen diving at 14,200 ft (4328 m) was not successful. Aspects considered were altitude adaptation, diminished air pressure diving, hypothermia, and remote area survival. Depths at altitude were converted to depths at sea level and were applied to the Royal Navy air tables. Altitude-related manifestations, hypoxia, hypothermia, suspected oxygen toxicity, and equipment failure were observed. It is concluded that stress is due to effects of altitude and cold on man and equipment, as well as changes in diving procedures when diving at high altitudes. Equivalent air depths when applied to Royal Navy tables could be considered a safe method for diving at altitudes.

  6. Application of regional climate models to the Indian winter monsoon over the western Himalayas.

    Science.gov (United States)

    Dimri, A P; Yasunari, T; Wiltshire, A; Kumar, P; Mathison, C; Ridley, J; Jacob, D

    2013-12-01

    The Himalayan region is characterized by pronounced topographic heterogeneity and land use variability from west to east, with a large variation in regional climate patterns. Over the western part of the region, almost one-third of the annual precipitation is received in winter during cyclonic storms embedded in westerlies, known locally as the western disturbance. In the present paper, the regional winter climate over the western Himalayas is analyzed from simulations produced by two regional climate models (RCMs) forced with large-scale fields from ERA-Interim. The analysis was conducted by the composition of contrasting (wet and dry) winter precipitation years. The findings showed that RCMs could simulate the regional climate of the western Himalayas and represent the atmospheric circulation during extreme precipitation years in accordance with observations. The results suggest the important role of topography in moisture fluxes, transport and vertical flows. Dynamical downscaling with RCMs represented regional climates at the mountain or even event scale. However, uncertainties of precipitation scale and liquid-solid precipitation ratios within RCMs are still large for the purposes of hydrological and glaciological studies.

  7. Seismic properties of naturally deformed quartzites of the Alaknanda valley, Garhwal Himalaya, India

    Indian Academy of Sciences (India)

    Ruchika Sharma Tandon; Vikram Gupta; Koushik Sen

    2015-08-01

    The present contribution summarizes the results of a study focusing on the influence of quartz microstructures on the seismic wave velocities in the quartzites of the Garhwal Himalaya. Quartzites being monomineralic were chosen for the present study so as to nullify the effect of other mineral constituents on the seismic velocity. Samples were collected from different tectonic settings of the Higher and Lesser Himalayas which are separated from one another by the major tectonic zone ‘Main Central Thrust’ (MCT). These are mainly Pandukeshwar quartzite, Tapovan quartzite and Berinag quartzite. The samples of Berinag quartzite were collected from near the klippen and the thrust, termed as Alaknanda Thrust. The vast differences in microstructures and associated seismic wave velocities have been noted in different quartzites. It has also been observed that quartzites of the MCT zone and Alaknanda Thrust have higher seismic velocities. This is because of their coarse-grained nature of the rocks as evidenced by the strong positive relation between seismic velocities and grain area. The coarsening is either due to the operation of grain boundary migration and grain area reduction process or high aspect ratio/shape preferred orientation. The quartzites located around Nandprayag Klippen have undergone static recrystallization and exhibit the lowest seismic wave velocities.

  8. Bamboo stumps as mosquito larval habitats in Darjeeling Himalayas,India:A spatial scale analysis

    Institute of Scientific and Technical Information of China (English)

    Gautam Aditya; Rakesh Tamang; Dipendra Sharma; Francis Subba; Goutam K.Saha

    2008-01-01

    Bamboo stumps can be a congenial breeding habitat of the mosquitoes.In view of this,a preliminary assessment of the dipteran immatures inhabiting the stumps of bamboo groves in the Darjeeling Himalayas was carried out at a spatial scale.Of the 104 stumps of Dendrocalamus hamiltoni surveyed,70 were found to host immatures of three dipteran species,the mosquitoes Aedes aegypti and Culex quinquefasciatus and the midges Chironomus sp.in varying densities.Though the stumps varied in diameter,in each stump on average 12.1 immatures were found.The abundance of the immatures was positively correlated with the diameter of the stumps (r = +0.382;P < 0.001) but negatively with the pH of the water present in the stumps (r = -0.336;P < 0.01).The coefficient of association was found to be +8.4 for the Ae.aegypti and Chironomus immatures,while in the rest of the species pair the association seemed to be independent.Thus it can be concluded that the stumps in the bamboo groves of Darjeeling Himalayas provides a favourable habitat for the mosquito and chironomid immatures.

  9. Aerosol Characteristics at a High Altitude Location in Central Himalayas: Optical Properties and Radiative Forcing

    CERN Document Server

    Pant, P; Dumka, U C; Sagar, R; Satheesh, S K; Moorthy, K K; Sagar, Ram

    2006-01-01

    Collocated measurements of the mass concentrations of aerosol black carbon (BC) and composite aerosols near the surface were carried out along with spectral aerosol optical depths (AODs) from a high altitude station, Manora Peak in Central Himalayas, during a comprehensive aerosol field campaign in December 2004. Despite being a pristine location in the Shivalik Ranges of Central Himalayas, and having a monthly mean AOD (at 500 nm) of 0.059 $\\pm$ 0.033 (typical to this site), total suspended particulate (TSP) concentration was in the range 15 - 40 micro g m^(-3) (mean value 27.1 $\\pm$ 8.3 micro g m^(-3)). Interestingly, aerosol BC had a mean concentration of 1.36 $\\pm$ 0.99 micro g m^(-3), contributed to ~5.0 $\\pm$ 1.3 % to the composite aerosol mass. This large abundance of BC is found to have linkages to the human activities in the adjoining valley and to the boundary layer dynamics. Consequently, the inferred single scattering albedo lies in the range of 0.87 to 0.94 (mean value 0.90 $\\pm$ 0.03), indicatin...

  10. Monazite geochronology unravels the timing of crustal thickening in NW Himalaya

    Science.gov (United States)

    Stübner, Konstanze; Grujic, Djordje; Parrish, Randall R.; Roberts, Nick M. W.; Kronz, Andreas; Wooden, Joe; Ahmad, Talat

    2014-12-01

    Greenschist to amphibolite grade Haimanta metasediments of the NW Himalaya preserve much of the prograde metamorphic history of Eohimalayan crustal thickening, which has been erased by Oligo-/Miocene migmatization elsewhere in the Himalaya. Our zircon and monazite U/Th-Pb data unravel a multi-stage prograde metamorphic evolution. The earliest evidence of prograde Barrovian metamorphic monazite growth is ~ 41 Ma. Peak metamorphic conditions (~ 8-8.5 kbar, ~ 600-700 °C) were attained at 37-36 Ma and followed by a prolonged evolution at high temperatures with at least three distinct episodes of monazite growth, which may be related to the formation of the northern Himalayan nappes (e.g., Shikar Beh nappe, Nyimaling nappe). Rapid exhumation of the crystalline started at ~ 26 Ma and resulted in cooling through the muscovite 40Ar/39Ar closure temperature by 21.8 Ma. Although a local continuation of the South Tibetan detachment is not unambiguously identified in central Himachal Pradesh extrusion was likely facilitated by a system of several minor late Oligocene/early Miocene top-to-the-N to NE shear zones. In contrast to the crystalline of Zanskar and eastern Himachal Pradesh, extrusion was not accompanied by widespread decompression melting.

  11. Kashmir Basin Fault and its tectonic significance in NW Himalaya, Jammu and Kashmir, India

    Science.gov (United States)

    Shah, A. A.

    2015-10-01

    The Kashmir Basin Fault is located in the Jammu and Kashmir region of Kashmir Basin in NW Himalaya, India. It is a classic example of an out-of-sequence thrust faulting and is tectonically active as observed from multiple geological evidences. Its geomorphology, structure and lateral extent indicate significant accommodation of stress since long, which is further supported by the absence of a large earthquake in this region. It seems this fault is actively accommodating some portion of the total India-Eurasia convergence, apart from two well-recognised active structures the Medlicott-Wadia Thrust and the Main Frontal Thrust, which are referred in Vassallo et al. (Earth Planet Sci Lett 411:241-252, 2015). This requires its quantification and inclusion into slip distribution scheme of NW Himalaya. Therefore, it should be explored extensively because this internal out-of-sequence thrust could serve major seismic hazard in KB, repeating a situation similar to Muzaffarabad earthquake of Northern Pakistan in 2005.

  12. Thermo-kinematic evolution of the Annapurna-Dhaulagiri Himalaya, central Nepal: The Composite Orogenic System

    Science.gov (United States)

    Parsons, A. J.; Law, R. D.; Lloyd, G. E.; Phillips, R. J.; Searle, M. P.

    2016-04-01

    The Himalayan orogen represents a "Composite Orogenic System" in which channel flow, wedge extrusion, and thrust stacking operate in separate "Orogenic Domains" with distinct rheologies and crustal positions. We analyze 104 samples from the metamorphic core (Greater Himalayan Sequence, GHS) and bounding units of the Annapurna-Dhaulagiri Himalaya, central Nepal. Optical microscopy and electron backscatter diffraction (EBSD) analyses provide a record of deformation microstructures and an indication of active crystal slip systems, strain geometries, and deformation temperatures. These data, combined with existing thermobarometry and geochronology data are used to construct detailed deformation temperature profiles for the GHS. The profiles define a three-stage thermokinematic evolution from midcrustal channel flow (Stage 1, >700°C to 550-650°C), to rigid wedge extrusion (Stage 2, 400-600°C) and duplexing (Stage 3, modular components of a Composite Orogenic System. These Orogenic Domains may be active at the same time at different depths/positions within the orogen. The thermokinematic evolution of the Annapurna-Dhaulagiri Himalaya describes the migration of the GHS through these Orogenic Domains and reflects the spatial and temporal variability in rheological boundary conditions that govern orogenic systems.

  13. Widespread expansion of glacier moraine-dammed lakes in the Chinese Himalaya

    Science.gov (United States)

    Liu, Shiyin; Ng, Felix; Wang, Xin; Guo, Wanqin; Yao, Xiaojun; Yu, Pengchun; Xu, Junli; Ding, Yongjian

    2010-05-01

    More moraine-dammed lakes in the Himalaya may form and enlarge due to glacier retreat and increased meltwater availability under the climatic warming that has been recorded across this mountain range over the last few decades. Because of this, and because such lakes have caused major GLOF (glacial lake outburst flood) events before, international organisations have been developing lake inventories to evaluate flood risks in the Himalaya, mainly in the south. Here we present the first complete inventory of moraine-dammed lakes on the Chinese side, which shows expansion and formation dominate their behaviour from the 1970s to the 2000s. We found that while their number has remained at ≈1200, their combined area has drastically increased, and glacier retreat also helped focus this overall growth in a narrow elevation range where many large new lakes have appeared. Our discovery of a glacier-recession signal in the lakes' variation underlines the need to study the climatological and glaciological factors behind lake evolution.

  14. Vegetation dynamics at the upper elevational limit of vascular plants in Himalaya.

    Science.gov (United States)

    Dolezal, Jiri; Dvorsky, Miroslav; Kopecky, Martin; Liancourt, Pierre; Hiiesalu, Inga; Macek, Martin; Altman, Jan; Chlumska, Zuzana; Rehakova, Klara; Capkova, Katerina; Borovec, Jakub; Mudrak, Ondrej; Wild, Jan; Schweingruber, Fritz

    2016-05-04

    A rapid warming in Himalayas is predicted to increase plant upper distributional limits, vegetation cover and abundance of species adapted to warmer climate. We explored these predictions in NW Himalayas, by revisiting uppermost plant populations after ten years (2003-2013), detailed monitoring of vegetation changes in permanent plots (2009-2012), and age analysis of plants growing from 5500 to 6150 m. Plant traits and microclimate variables were recorded to explain observed vegetation changes. The elevation limits of several species shifted up to 6150 m, about 150 vertical meters above the limit of continuous plant distribution. The plant age analysis corroborated the hypothesis of warming-driven uphill migration. However, the impact of warming interacts with increasing precipitation and physical disturbance. The extreme summer snowfall event in 2010 is likely responsible for substantial decrease in plant cover in both alpine and subnival vegetation and compositional shift towards species preferring wetter habitats. Simultaneous increase in summer temperature and precipitation caused rapid snow melt and, coupled with frequent night frosts, generated multiple freeze-thaw cycles detrimental to subnival plants. Our results suggest that plant species responses to ongoing climate change will not be unidirectional upward range shifts but rather multi-dimensional, species-specific and spatially variable.

  15. Radon and thoron monitoring in the environment of Kumaun Himalayas: survey and outcomes

    Energy Technology Data Exchange (ETDEWEB)

    Ramola, R.C. E-mail: rcramola@sancharnet.in; Negi, M.S.; Choubey, V.M

    2005-07-01

    Monitoring of radon, thoron and their daughter products was carried out in houses of Kumaun Himalaya, India using LR-115 plastic track detectors. The measurements were made in residential houses from June 1999 to May 2000 at a height of 2.5 m from ground level using a twin chamber radon dosimeter. The twin chamber radon dosimeter can record the values of radon, thoron and their decay products separately. Maximum and minimum indoor radon and thoron concentrations were evaluated and activity concentrations of radon and thoron daughters were estimated. The resulting dose rates due to radon, thoron and their decay products varied from 0.04 to 1.89 {mu}Sv/h. A detailed analysis of the distribution of radon, thoron and their decay products inside the house is also reported. The observed dose rates inside the houses of Kumaun Himalaya were found to be lower than the ICRP recommended value of 200 Bq/m{sup 3} and thus are within safe limits.

  16. Phenotypic differentiation of Barilius bendelisis (Cypriniformes: Cyprinidae) in four rivers from Central Indian Himalaya.

    Science.gov (United States)

    Mir, Javaid Iqbal; Saxena, Neha; Patiyal, Rabindar Singh; Sahoo, Prabhati Kumari

    2015-03-01

    Barilius bendelisis, commonly known as Indian Hill Trout is an upland water fish of South East Asia. It belongs to the family Cyprinidae and dwells in shallow, clear and cold water. In this study, the intraspecific variation of Barilius bendelisis, on the basis of morphometric characters, was investigated. Altogether, 402 specimens were collected from four rivers in the Central Indian Himalaya. A truss network was constructed by interconnecting 12 landmarks to yield 30 distance variables that were extracted from digital images of specimens using tpsDig2 and PAST software. Allometric transformed truss measurements were subjected to univariate analysis of variance, factor analysis and discriminant analysis. All variables exhibited significant differences between the populations. Altogether 88% of the specimens were classified into their original populations (81.98% under a 'leave-one-out' procedure). With factor analysis measurements of the head region, the middle portion and the caudal region had high loadings on the first and second axis. The results indicated that B. bendelisis has significant phenotypic heterogeneity between the geographically isolated regions of Central Indian Himalaya. We hypothesize that the marked interspecific variation in B. bendelisis is the result of local ecological conditions.

  17. Longest time series of glacier mass changes in the Himalaya based on stereo imagery

    Science.gov (United States)

    Bolch, T.; Pieczonka, T.; Benn, D. I.

    2010-12-01

    Mass loss of Himalayan glaciers has wide-ranging consequences such as declining water resources, sea level rise and an increasing risk of glacial lake outburst floods (GLOFs). The assessment of the regional and global impact of glacier changes in the Himalaya is, however, hampered by a lack of mass balance data for most of the range. Multi-temporal digital terrain models (DTMs) allow glacier mass balance to be calculated since the availability of stereo imagery. Here we present the longest time series of mass changes in the Himalaya and show the high value of early stereo spy imagery such as Corona (years 1962 and 1970) aerial images and recent high resolution satellite data (Cartosat-1) to calculate a time series of glacier changes south of Mt. Everest, Nepal. We reveal that the glaciers are significantly losing mass with an increasing rate since at least ~1970, despite thick debris cover. The specific mass loss is 0.32 ± 0.08 m w.e. a-1, however, not higher than the global average. The spatial patterns of surface lowering can be explained by variations in debris-cover thickness, glacier velocity, and ice melt due to exposed ice cliffs and ponds.

  18. Wintertime land surface characteristics in climatic simulations over the western Himalayas

    Indian Academy of Sciences (India)

    A P Dimri

    2012-04-01

    Wintertime regional climate studies over the western Himalayas with ICTP-RegCM3 simulations through 22 years has shown systematic biases in precipitation and temperature fields. The model simulated precipitation shows systematically wet bias. In surface temperature simulations, positive and negative biases of 2°–4°C occurred. Experiment without (CONT) and with subBATS (SUB) shows that later scheme performs better, especially for precipitation. Apart from the role of topography and model internal variability, land surface characteristics also have profound impact on these climatic variables. Therefore, in the present study, impacts of land surface characteristics are investigated through cool/wet and warm/dry winter climate by CONT and SUB simulations to assess systematic biases. Since SUB experiment uses detailed land-use classification, systematic positive biases in temperature over higher elevation peaks are markedly reduced. The change has shown reduced excessive precipitation as well. Most of the surface characteristics show that major interplay between topography and western disturbances (WDs) takes place along the foothills rather than over the higher peaks of the western Himalayas.

  19. Observed linear trend in few surface weather elements over the Northwest Himalayas (NWH) during winter season

    Indian Academy of Sciences (India)

    Dan Singh; Vikas Sharma; Vikas Juyal

    2015-04-01

    Linear trends in few surface weather variables such as air temperatures (maximum temperature, minimum temperature), snow and rainy days, snowfall and rainfall amounts, rainfall contribution to seasonal total precipitation amount, seasonal snow cover depth and snow cover days (duration) are examined from winter-time observations at 11 stations located over the Northwest Himalayas (NWH). This study indicates that snowfall tends to show a decline in this region, while the rainfall tends to increase during the winter months. Seasonal snow cover depth and seasonal snow cover days also tend to show a decline over the NWH. Decrease in seasonal snow cover depth and duration have reduced the winter period in terms of availability of seasonal snow cover over the NWH during the last 2–3 decades. Other surface weather variables also exhibited significant temporal changes in recent decades. Observed trends in temperature and precipitation over the NWH in recent decades are also supported by long data series of temperature over the western Himalayas (WH), north mountain India (NMI) rainfall data and reanalysis products.

  20. Use of objective analysis to estimate winter temperature and precipitation at different stations over western Himalaya

    Indian Academy of Sciences (India)

    Jagdish Chandra Joshi; Ashwagosha Ganju

    2010-10-01

    Temperature and fresh snow are essential inputs in an avalanche forecasting model.Without these parameters,prediction of avalanche occurrence for a region would be very difficult.In the complex terrain of Himalaya,nonavailability of snow and meteorological data of the remote locations during snow storms in the winter is a common occurrence.In view of this persistent problem present study estimates maximum temperature,minimum temperature,ambient temperature and precipitation intensity on different regions of Indian western Himalaya by using similar parameters of the neighbouring regions.The location at which parameters are required and its neighbouring locations should all fall in the same snow climatic zone.Initial step to estimate the parameters at a location,is to shift the parameters of neighbouring regions at a reference height corresponding to the altitude of the location at which parameters are to be estimated.The parameters at this reference height are then spatially interpolated by using Barnes objective analysis.The parameters estimated on different locations are compared with the observed one and the Root Mean Square Errors (RMSE)of the observed and estimated values of the parameters are discussed for the winters of 2007 –2008.

  1. Longest time series of glacier mass changes in the Himalaya based on stereo imagery

    Directory of Open Access Journals (Sweden)

    T. Bolch

    2010-12-01

    Full Text Available Mass loss of Himalayan glaciers has wide-ranging consequences such as declining water resources, sea level rise and an increasing risk of glacial lake outburst floods (GLOFs. The assessment of the regional and global impact of glacier changes in the Himalaya is, however, hampered by a lack of mass balance data for most of the range. Multi-temporal digital terrain models (DTMs allow glacier mass balance to be calculated since the availability of stereo imagery. Here we present the longest time series of mass changes in the Himalaya and show the high value of early stereo spy imagery such as Corona (years 1962 and 1970 aerial images and recent high resolution satellite data (Cartosat-1 to calculate a time series of glacier changes south of Mt. Everest, Nepal. We reveal that the glaciers are significantly losing mass with an increasing rate since at least ~1970, despite thick debris cover. The specific mass loss is 0.32 ± 0.08 m w.e. a−1, however, not higher than the global average. The spatial patterns of surface lowering can be explained by variations in debris-cover thickness, glacier velocity, and ice melt due to exposed ice cliffs and ponds.

  2. A CERN flag is set to wave up in the Himalayas

    CERN Multimedia

    Roberto Cantoni

    2010-01-01

    On 18 October, Hubert Reymond, from the Industrial Controls and Engineering group of the EN Department, will be leaving to Nepal with a CERN flag in his backpack. He will place it at the highest point of his trek across the Annapurna mountains in the Himalayas, Thorong La pass, at 5,416 m above sea level.   A view of the Annapurna mountains (source: www.flickr.com/minutesalone) “Is there any official CERN flag I can carry with me during my trek through Nepal?” Some days ago, the Press Office was confronted with this unusual (but see box) question from Hubert Reymond. From 18 October to 10 November, Reymond, who works as an industrial computing engineer in the EN Department, will be trekking across the 55 km-long Annapurna massif in the Himalayas, whose highest point lies at 8,091 m (making it the 10th-highest summit in the world). The area is well-known to trekkers from around the world, as it includes several world-class circuits, including the Annapurna circuit which Reym...

  3. Paternal-specific S-allele transmission in sweet cherry (Prunus avium L.): the potential for sexual selection.

    Science.gov (United States)

    Hedhly, A; Wünsch, A; Kartal, Ö; Herrero, M; Hormaza, J I

    2016-03-01

    Homomorphic self-incompatibility is a well-studied example of a physiological process that is thought to increase population diversity and reduce the expression of inbreeding depression. Whereas theoretical models predict the presence of a large number of S-haplotypes with equal frequencies at equilibrium, unequal allele frequencies have been repeatedly reported and attributed to sampling effects, population structure, demographic perturbation, sheltered deleterious mutations or selection pressure on linked genes. However, it is unclear to what extent unequal segregations are the results of gametophytic or sexual selection. Although these two forces are difficult to disentangle, testing S-alleles in the offspring of controlled crosses provides an opportunity to separate these two phenomena. In this work, segregation and transmission of S-alleles have been characterized in progenies of mixed donors and fully compatible pollinations under field conditions in Prunus avium. Seed set patterns and pollen performance have also been characterized. The results reveal paternal-specific distorted transmission of S-alleles in most of the crosses. Interestingly, S-allele segregation within any given paternal or maternal S-locus was random. Observations on pollen germination, pollen tube growth rate, pollen tube cohort size, seed set dynamics and transmission patterns strongly suggest post-pollination, prezygotic sexual selection, with male-male competition as the most likely mechanism. According to these results, post-pollination sexual selection takes precedence over frequency-dependent selection in explaining unequal S-haplotype frequencies.

  4. Plants of the Cerrado naturally selected by grazing sheep may have potential for inhibiting development of Haemonchus contortus larva.

    Science.gov (United States)

    Morais-Costa, Franciellen; Soares, Ana Cláudia Maia; Bastos, Gabriela Almeida; Nunes, Yule Roberta Ferreira; Geraseev, Luciana Castro; Braga, Fernão Castro; Dos Santos Lima, Walter; Duarte, Eduardo Robson

    2015-10-01

    Plant species naturally selected by sheep grazing in the Cerrado region of Brazil were assessed in vitro for activity against Haemonchus contortus. One year of observations showed the plant families in the region exhibiting greatest richness to be Fabaceae, Rubiaceae, Malpighiaceae, Bignoniaceae, Myrtaceae, and Annonaceae. Nine species commonly selected by grazing sheep showed variation in the selectivity index with respect to the dry and rainy seasons. Coproculture was conducted in five replicates of 11 treatments: ivermectin, distilled water, or dehydrated leaves of nine selected plant species administered at 333.3 mg g(-1) fecal culture. The dried powder of Piptadenia viridiflora and Ximenia americana leaves significantly reduced the number of infective larvae compared to the distilled water control. These species showed efficacy of over 85 % despite low concentrations of proanthocyanidin. High-performance liquid chromatography analyses of extracts of these plants showed major peaks of UV spectra characteristic of flavonoids. Those naturally selected plant species with high antihelminthic efficacy show promise for use in diet as an alternative control of H. contortus in sheep.

  5. Erosion in southern Tibet shut down at ∼10 Ma due to enhanced rock uplift within the Himalaya

    Science.gov (United States)

    Tremblay, Marissa M.; Fox, Matthew; Schmidt, Jennifer L.; Tripathy-Lang, Alka; Wielicki, Matthew M.; Harrison, T. Mark; Zeitler, Peter K.; Shuster, David L.

    2015-01-01

    Exhumation of the southern Tibetan plateau margin reflects interplay between surface and lithospheric dynamics within the Himalaya–Tibet orogen. We report thermochronometric data from a 1.2-km elevation transect within granitoids of the eastern Lhasa terrane, southern Tibet, which indicate rapid exhumation exceeding 1 km/Ma from 17–16 to 12–11 Ma followed by very slow exhumation to the present. We hypothesize that these changes in exhumation occurred in response to changes in the loci and rate of rock uplift and the resulting southward shift of the main topographic and drainage divides from within the Lhasa terrane to their current positions within the Himalaya. At ∼17 Ma, steep erosive drainage networks would have flowed across the Himalaya and greater amounts of moisture would have advected into the Lhasa terrane to drive large-scale erosional exhumation. As convergence thickened and widened the Himalaya, the orographic barrier to precipitation in southern Tibet terrane would have strengthened. Previously documented midcrustal duplexing around 10 Ma generated a zone of high rock uplift within the Himalaya. We use numerical simulations as a conceptual tool to highlight how a zone of high rock uplift could have defeated transverse drainage networks, resulting in substantial drainage reorganization. When combined with a strengthening orographic barrier to precipitation, this drainage reorganization would have driven the sharp reduction in exhumation rate we observe in southern Tibet. PMID:26371325

  6. Mapping regional distribution of land surface heat fluxes on the southern side of the central Himalayas using TESEBS

    Science.gov (United States)

    Amatya, Pukar Man; Ma, Yaoming; Han, Cunbo; Wang, Binbin; Devkota, Lochan Prasad

    2016-05-01

    Recent scientific studies based on large-scale climate model have highlighted the importance of the heat release from the southern side of the Himalayas for the development of South Asian Summer Monsoon. However, studies related to land surface heat fluxes are nonexistent on the southern side. In this study, we test the feasibility of deriving land surface heat fluxes on the central Himalayan region using Topographically Enhanced Surface Energy Balance System (TESEBS), which is forced by MODIS land surface products and Global Land Data Assimilation System (GLDAS) meteorological data. The model results were validated using the first eddy covariance measurement system established in the southern side of the central Himalayas. The derived land surface heat fluxes were close to the field measurements with mean bias of 15.97, -19.89, 8.79, and -20.39 W m-2 for net radiation flux, ground heat flux, sensible heat flux, and latent heat flux respectively. Land surface heat fluxes show strong contrast in pre monsoon, summer monsoon, post monsoon, and winter seasons and different land surface states among the different physiographic regions. In the central Himalayas, the latent heat flux is the dominant consumer of available energy for all physiographic regions except for the High Himalaya where the sensible heat flux is high.

  7. Reorientation of lineation in the Central Crystalline Zone, Munsiari–Milam area of the Kumaun Greater Himalaya

    Indian Academy of Sciences (India)

    A K Verma; A R Bhattacharya

    2015-03-01

    During large scale ductile shear deformation, linear features of the rocks tend to be reoriented towards the direction of bulk shear. This is demonstrated in a crustal scale shear zone of the Himalaya, the Main Central Thrust (MCT), typically exposed in the Munsiari–Milam area of eastern Kumaun Greater Himalaya. Along the MCT, the crystalline rocks of the Greater Himalaya are thrust over the younger sedimentary belt of the Lesser Himalaya. In the study area, the scatter of lineation orientation in the vicinity of the MCT has been observed to drastically reduce within 27° in a zone of about 18 km (about 13 km in the crystalline rocks and about 5 km in the sedimentary rocks). Beyond this zone, the scatter is very high, up to 70° or more. The low scatter of lineation orientation around the MCT could be related to the strong ductile shear deformation associated with the movement along this thrust due to which the linear features got reoriented towards the direction of bulk shear. Away from this zone, ductile shearing had negligible or no effect on the rocks and, therefore, the scatter of lineation remains very high.

  8. Elevational gradients in bird diversity in the Eastern Himalaya: An evaluation of distribution patterns and their underlying mechanisms

    DEFF Research Database (Denmark)

    Acharya, Bhoj Kumar; Sanders, Nathan J.; Vijayan, Lalitha;

    2011-01-01

    richness, shrub density and basal area of trees) accounted for most of the variation in bird species richness. We also observed that ranges of most bird species were narrow along the elevation gradient. We find little evidence to support Rapoport's rule for the birds of Sikkim region of the Himalaya...

  9. Mammals of the high altitudes of western Arunachal Pradesh, eastern Himalaya: an assessment of threats and conservation needs

    NARCIS (Netherlands)

    Mishra, C.; Madhusudan, M.D.; Datta, A.

    2006-01-01

    he high altitudes of Arunachal Pradesh, India, located in the Eastern Himalaya biodiversity hotspot, remain zoologically unexplored and unprotected. We report results of recent mammal surveys in the high altitude habitats of western Arunachal Pradesh. A total of 35 mammal species (including 12 carni

  10. The Tethyan Himalayan detrital record shows that India-Asia terminal collision occurred by 54 Ma in the Western Himalaya

    Science.gov (United States)

    Najman, Y.; Jenks, D.; Godin, L.; Boudagher-Fadel, M.; Millar, I.; Garzanti, E.; Horstwood, M.; Bracciali, L.

    2017-02-01

    The Himalayan orogen is a type example of continent-continent collision. Knowledge of the timing of India-Asia collision is critical to the calculation of the amount of convergence that must have been accommodated and thus to models of crustal deformation. Sedimentary rocks on the Indian plate near the suture zone can be used to constrain the time of collision by determining first evidence of Asian-derived material deposited on the Indian plate. However, in the Himalaya, for this approach to be applied successfully, it is necessary to be able to distinguish between Asian detritus and detritus from oceanic island arcs that may have collided with India prior to India-Asia collision. Zircons from the Indian plate, Asian plate and Kohistan-Ladakh Island arc can be distinguished based on their U-Pb ages combined with Hf signatures. We undertook a provenance study of the youngest detrital sedimentary rocks of the Tethyan Himalaya of the Indian plate, in the Western Himalaya. We show that zircons of Asian affinity were deposited on the Indian plate at 54 Ma. We thus constrain terminal India-Asia collision, when both sutures north and south of the Kohistan-Ladakh Island arc were closed, to have occurred in the Western Himalaya by 54 Ma.

  11. Green Tourism in Mountain Regions - Reducing Vulnerability and Promoting People and Place Centric Development in the Himalayas

    Institute of Scientific and Technical Information of China (English)

    R. B. Singh; D. K. Mishra

    2004-01-01

    In recent years, mountain regions are attracting great attention to Indian tourists in general and foreign tourists in particular. The potential mountain resources for promoting green tourism are enormous in the form of natural and cultural heritage such as biosphere reserves, flora and fauna, lakes and rivers and traditional rural resources. In order to utilise tourism industry market, uncontrolled numbers of tourists and related haphazard infrastructural facilities in the vulnerable mountain regions pose serious environmental implications. The ecological pressures are threatening land, water and wild life resources through direct and indirect environmental impacts together with generation of solid and liquid wastes, so green tourism is emerging as an important task in order to develop new relationship between communities, government agencies and private sectors. The strategy focuses on ecological understanding, environmental protection and ecodevelopment. The major attributes of the green tourism include environmental conservation and education and distribution of income to local people based on strong partnership. Various knowledge systems go a long way for achieving the goals of the green tourism, which creates awareness about the value of environmental resources.Mountains have ecological, recreational, educational and scientific values, which need to be utilised in sustainable way. Various tourist activities and facilities need to be diversified in order to achieve multiple benefits including scientific field excursion,recreation in natural and cultural areas, community festivals and sport tourisms. Green tourism considers tourism development as an integral part of a national and regional development. The paper discusses the social, economic and environmental dimensions of the green tourism with particular reference to village tourism development programme taking empirical evidences from the Himalaya. Such programme also minimises biophysical and human

  12. Surface characteristics of debris-covered glacier tongues in the Khumbu Himalaya derived from remote sensing texture analysis

    Science.gov (United States)

    Racoviteanu, Adina; Arnaud, Yves; Nicholson, Lindsay

    2013-04-01

    The delineation of debris-covered glaciers remains a challenge in optical remote sensing, due to the similarity of the spectral signature of debris-covered ice to surrounding lateral moraines, making it difficult to apply standard semi-automated algorithms commonly used for clean ice delineation. Furthermore, supraglacial debris exhibits considerable spatial variability in its characteristics such as debris cover thickness, particle size, thermal resistance and thermal conductivity. These properties are needed in order to map the extent of debris cover and to estimate ice melt under the debris cover or at the surface. In this study we evaluate the potential of texture analysis for detecting surface characteristics of debris-cover glacier tongues in the Khumbu Himalaya, using Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) and high-resolution Ikonos data. We focus on mapping supra-glacier lakes and exposed ice walls using texture analysis algorithms such as grey-level co-occurrence measures (GLCM), filtering, image segmentation, and particle boundaries. We compare the performance of various existing commercial software suitable for texture analysis such as ERDAS Objective, Aphelion, as well as public domain image display and analysis software used originally for medical analysis, notably Image SXM and ImageJ. Preliminary results based on geostatistics and GLCM measures show differences in surface roughness of debris cover when compared to surrounding ice-free moraines. We expand on these results and aim at developing a quasi-automated algorithm for extracting surface features, which will be used as input in an energy balance model for estimating melting under debris cover as well as surface ice melt.

  13. Population structure and regeneration patterns of tree species in cli-mate-sensitive subalpine forests of Indian western Himalaya

    Institute of Scientific and Technical Information of China (English)

    Sanjay Gairola; R. S. Rawal; N. P. Todaria; Arvind Bhatt

    2014-01-01

    The population structure of tree species has been explored in order to elucidate regeneration potential of the subalpine forests of Indian western Himalaya. For this study, the subalpine forest area was divided into three strata, i.e., lower altitude (3200m). Considering the major compositional attributes, an increase in altitude came with a significant decline in tree density and the total basal area for all the sites. However, no such clear trends were observed for recruits (i.e., seedlings and saplings). Seedling density did not exhibit uniform patterns for sites and altitude strata. In general, overall seedling density was greater at the Pindari site compared to the Lata and Tungnath sites. By comparison, significant variation in seedling density along the altitude strata was recorded for the Tungnath and Pindari sites only. Likewise, sapling density patterns varied across the sites and altitude strata, and significant variation in sapling density along the altitude strata was recorded only for the Lata site. At the Pin-dari site, the continuous increase in sapling density along with increasing altitude was revealing. The Pindari forests of exhibited expanding popu-lation structure. In contrast, greater accumulation of individuals in the sapling class and sharp decline toward both higher tree classes and lower seedling classes was generally apparent for the Lata and Tungnath sites. This indicates that the replacement in tree size classes from sapling stage is not proportional and the population may decline in the long-term. Considerable variation in patterns of forest and dominant species popula-tion structure were evident across altitude strata. But in all cases irrespec-tive of sites, we found growth at the high-altitude stratum, in the form of entire forests or dominant species. This trend deserves further investiga-tion to explore its relevance under changing climate scenarios.

  14. Transport of sediments in Himalaya-Karakorum and its influence on hydropower plants; Sedimenttransportprozesse im Himalaya-Karakorum und ihre Bedeutung fuer Wasserkraftanlagen

    Energy Technology Data Exchange (ETDEWEB)

    Palt, S.M.

    2001-07-01

    In the present study the sediment transport processes in alpine mountain areas and their impact on hydropower development projects are investigated. The aim of the present work is to contribute to the understanding of the transport process system, which is characterized by high magnitude-low frequency - events, to ensure an appropriate layout of high head hydropower projects in mountain regions. The sediment transport in large areas in the macro scale is triggered by natural hazards, such as earthquakes, rock slides, earth movements, debris flows, glacial lake outbursts and floods. The basic principle of complex transport processes in this scale is described and explained on the example of the Himalaya-Karakorum-region. The sediment transport process in the smaller scale, so called meso scale, is investigated by means of extensive field measurements at river reaches of 16 different mountain rivers of a 80000 km{sup 2} large project area. The measurements include topographic survey works and measurements of discharge, bed load and suspended load. Since the conditions of mountain rivers in terms of size of bed material as well as available flow velocities can be considered as extreme, an appropriate bed load sampler named B-69 was developed, constructed and used in the field. Moreover the hydraulic as well as the sedimentological efficiency of the sampler was tested in the laboratory tests. Due to the nice performance of the bed load sampler B-69 at high flow velocities it might be useful for flood conditions in gravel-bed rivers in other parts of the world as well. Based on the results of the study the parameter of the river slope can be considered as the most important one for the characteristics of the morphology, the flow conditions, the bed stability as well as the bed load transport in steep mountain rivers. With increasing slope morphological structures in the longitudinal direction will develop from flat bed conditions. The so called step-pool-systems consist

  15. Impact of initial and boundary conditions on regional winter climate over the Western Himalayas: A fixed domain size experiment

    Science.gov (United States)

    Maharana, P.; Dimri, A. P.

    2014-03-01

    The Western Himalayas during winter receives precipitation due to the eastward moving low pressure synoptic weather systems, called Western Disturbances (WDs) in Indian meteorological parlance. The complex Himalayan topography, sparse observational data, less understanding of physical processes, etc. form many interesting research questions over this region. One of the important research goals is to study the change in the winter (Dec., Jan. and Feb. - DJF) climate over the Himalayas. In the presented study with modelling efforts having varying initial and boundary conditions (ICBC) with same model physics option is attempted to provide a comment on important physical processes pertaining to precipitation and temperature fields. A 22 year (1980-2001) simulation with Regional Climate Model version 3 (RegCM3) forced with National Centre for Environmental Prediction/National Centre for Atmospheric Research (NCEP/NCAR) reanalysis 1 (NNRP1), NCEP/NCAR reanalysis 2 (NNRP2) and European Centre for Medium Range Weather Forecast 40 Year reanalysis (ERA40) as three different ICBC is carried out. The present study focuses on the winter climatology of the main meteorological parameters viz., temperature, precipitation and snow depth and interannual variability of winter seasonal precipitation. The model shows overestimation of seasonal average precipitation and underestimation of seasonal average temperature fields over the Western Himalayas in all the three model simulations. The interannual variability of precipitation and temperature over this region is nicely captured by the model. The model simulation with NNRP2 as the ICBC shows more realistic results. In addition the ensemble mean of the three simulations has shown improved results and is closer to the abovementioned simulation. Precipitation bias explained in terms of the higher vertical integrated moisture flux and transport shows strong convergence zone over and along the southern rim of the Indian Himalayas. The

  16. Selection of candidate container materials for the conceptual waste package design for a potential high level nuclear waste repository at Yucca Mountain

    Energy Technology Data Exchange (ETDEWEB)

    Van Konynenburg, R.A.; Halsey, W.G.; McCright, R.D.; Clarke, W.L. Jr. [Lawrence Livermore National Lab., CA (United States); Gdowski, G.E. [KMI, Inc., Albuquerque, NM (United States)

    1993-02-01

    Preliminary selection criteria have been developed, peer-reviewed, and applied to a field of 41 candidate materials to choose three alloys for further consideration during the advanced conceptual design phase of waste package development for a potential high level nuclear waste repository at Yucca Mountain, Nevada. These three alloys are titanium grade 12, Alloy C-4, and Alloy 825. These selections are specific to the particular conceptual design outlined in the Site Characterization Plan. Other design concepts that may be considered in the advanced conceptual design phase may favor other materials choices.

  17. Modelling glacier change in the Everest region, Nepal Himalaya

    Science.gov (United States)

    Shea, J. M.; Immerzeel, W. W.; Wagnon, P.; Vincent, C.; Bajracharya, S.

    2015-05-01

    In this study, we apply a glacier mass balance and ice redistribution model to examine the sensitivity of glaciers in the Everest region of Nepal to climate change. High-resolution temperature and precipitation fields derived from gridded station data, and bias-corrected with independent station observations, are used to drive the historical model from 1961 to 2007. The model is calibrated against geodetically derived estimates of net glacier mass change from 1992 to 2008, termini position of four large glaciers at the end of the calibration period, average velocities observed on selected debris-covered glaciers, and total glacierized area. We integrate field-based observations of glacier mass balance and ice thickness with remotely sensed observations of decadal glacier change to validate the model. Between 1961 and 2007, the mean modelled volume change over the Dudh Koshi basin is -6.4 ± 1.5 km3, a decrease of 15.6% from the original estimated ice volume in 1961. Modelled glacier area change between 1961 and 2007 is -101.0 ± 11.4 km2, a decrease of approximately 20% from the initial extent. The modelled glacier sensitivity to future climate change is high. Application of temperature and precipitation anomalies from warm/dry and wet/cold end-members of the CMIP5 RCP4.5 and RCP8.5 ensemble results in sustained mass loss from glaciers in the Everest region through the 21st century.

  18. Modelling glacier change in the Everest region, Nepal Himalaya

    Directory of Open Access Journals (Sweden)

    J. M. Shea

    2014-10-01

    Full Text Available In this study, we apply a glacier mass balance and ice redistribution model to simulate historical and future glacier change in the Everest region of Nepal. High-resolution temperature and precipitation fields derived from gridded APHRODITE data, and validated against independent station observations from the EVK2CNR network, are used to drive the historical model from 1961 to 2007. The model is calibrated against geodetically derived estimates of net glacier mass change from 1992 to 2008, termini position of four large glaciers at the end of the calibration period, average velocities observed on selected debris-covered glaciers, and total glacierized area. We integrate field-based observations of glacier mass balance and ice thickness with remotely-sensed observations of decadal glacier change to validate the model. Between 1961 and 2007, the mean modelled volume change over the Dudh Kosi basin is −6.4 ± 1.5 km3, a decrease of 15.6% from the original estimated ice volume in 1961. Modelled glacier area change between 1961 and 2007 is −101.0 ± 11.4 km2, a decrease of approximately 20% from the initial extent. Scenarios of future climate change, based on CMIP5 RCP4.5 and RCP8.5 end members, suggest that glaciers in the Everest region will continue to lose mass through the 21st century. Glaciers in the basin are concentrated between 5000 and 6000 m of elevation, and are thus expected to be sensitive to changes in temperature and equilibrium line altitude (ELA. Glacier volume reductions between −35 to −62% are possible by 2050, and sustained temperature increases to 2100 may result in total glacier volume losses of between −73 and −96%.

  19. Assessment of the in vitro antiprotozoal and cytotoxic potential of 20 selected medicinal plants from the island of Soqotra.

    Science.gov (United States)

    Mothana, Ramzi A; Al-Musayeib, Nawal M; Matheeussen, An; Cos, Paul; Maes, Louis

    2012-12-03

    Malaria, leishmaniasis and human African trypanosomiasis continue to be major public health problems in need of new and more effective drugs. The aim of this study was to evaluate in vitro antiprotozoal activity of twenty endemic medicinal plants collected from the island of Soqotra in the Indian Ocean. The plant materials were extracted with methanol and tested for antiplasmodial activity against erythrocytic schizonts of Plasmodium falciparum, for antileishmanial activity against intracellular amastigotes of Leishmania infantum and for antitrypanosomal activity against intracellular amastigotes of Trypanosoma cruzi and free trypomastigotes of T. brucei. To assess selectivity, cytotoxicity was determined against MRC-5 fibroblasts. Selective activity was obtained for Punica protopunica against Plasmodium (IC₅₀ 2.2 µg/mL) while Eureiandra balfourii and Hypoestes pubescens displayed activity against the three kinetoplastid parasites (IC₅₀ cinnabari and Euphorbia socotrana displayed non-specific inhibition of the parasites related to high cytotoxicity.

  20. Identification of potential nuclear reprogramming and differentiation factors by a novel selection method for cloning chromatin-binding proteins

    Institute of Scientific and Technical Information of China (English)

    LiuWang; AihuaZheng; LingYi; ChongrenXu; MingxiaoDing; HongkuiDeng

    2005-01-01

    Nuclear reprogramming is critical for animal cloning and stem cell creation through nuclear transfer, which requires extensive remodeling of chromosomal architecture involving dramatic changes in chromatin-binding proteins. To understand the mechanism of nuclear reprogramming, it is critical to identify chromatin-binding factors specify the reprogramming process. In this report, we have developed a high-throughput selection method, based on T7 phage display and chromatin immunoprecipitation, to isolate chromatin-binding factors expressed in mouse embryonic stem cells using primary mouse embryonic fibroblast chromatin. Seven chromatin-binding proteins have been isolated by this method. We have also isolated several chromatin-binding proteins involved in hepatocyte differentiation. Our method provides a powerful tool to rapidly and selectively identify chromatin-binding proteins. The method can be used to study epigenetic modification of chromatin during nuclear reprogramming, cell differentiation, and transdifferentiation.

  1. Synthesis and characterization of selected methyl 5-methoxy-2-methyl-1-benzofuran-3-carboxylate derivatives with potential antimicrobial activity.

    Science.gov (United States)

    Krawiecka, Mariola; Kuran, Bozena; Kossakowski, Jerzy; Wolska, Irena; Kierzkowska, Marta; Młynarczyk, Grazyna

    2012-01-01

    Halogen and aminoalkyl derivatives of methyl 5-methoxy-2-methyl-1-benzofuran-3-carboxylate were prepared using 5-hydroxy-2-methyl-3-benzofuranocarboxylic acid as starting material. (1)H-NMR spectra were obtained for all of the synthesized structures, and for compounds 1 and 2 X-ray crystal structures were obtained too. All derivatives were tested for antimicrobial activity against a selection of Gram-positive cocci, Gram-negative rods and yeasts.

  2. Vertebrate hosts as islands: dynamics of selection, immigration, loss, persistence and potential function of bacteria on salamander skin

    Directory of Open Access Journals (Sweden)

    Andrew Howard Loudon

    2016-03-01

    Full Text Available Skin bacterial communities can protect amphibians from a fungal pathogen; however, little is known about how these communities are maintained. We used a neutral model of community ecology to identify bacteria that are maintained on salamanders by selection or by dispersal from a bacterial reservoir (soil and ecological drift. We found that 75% (9/12 of bacteria that were consistent with positive selection, < 1% of bacteria that were consistent with random dispersal and none of the bacteria that were consistent under negative selection had a 97% or greater match to antifungal isolates. Additionally we performed an experiment where salamanders were either provided or denied a bacterial reservoir and estimated immigration and loss (emigration and local extinction rates of bacteria on salamanders in both treatments. Loss was strongly related to bacterial richness, suggesting competition is important for structuring the community. Bacteria closely related to antifungal isolates were more likely to persist on salamanders with or without a bacterial reservoir, suggesting they had a competitive advantage. Furthermore, over-represented and under-represented OTUs had similar persistence on salamanders when a bacterial reservoir was present. However, under-represented OTUs were less likely to persist in the absence of a bacterial reservoir, suggesting that the over-represented and under-represented bacteria are selected for or against on salamanders through time. Our findings from the neutral model, migration and persistence analyses show that bacteria that exhibit a high similarity to antifungal isolates persist on salamanders, which likely protect hosts against pathogens and improve fitness. This research is one of the first to apply ecological theory to investigate assembly of host associated-bacterial communities, which can provide insights for probiotic bioaugmentation as a conservation strategy against disease.

  3. Bio-active glass air-abrasion has the potential to remove resin composite restorative material selectively

    Energy Technology Data Exchange (ETDEWEB)

    Milly, Hussam [Biomaterials, Biomimetics and Biophotonics Research Group, Kings College London Dental Institute at Guy' s Hospital, King' s Health Partners, London (United Kingdom); Andiappan, Manoharan [Unit of Dental Public Health, Kings College London Dental Institute at Guy' s Hospital, King' s Health Partners, London (United Kingdom); Thompson, Ian [Biomaterials, Biomimetics and Biophotonics Research Group, Kings College London Dental Institute at Guy' s Hospital, King' s Health Partners, London (United Kingdom); Banerjee, Avijit, E-mail: avijit.banerjee@kcl.ac.uk [Biomaterials, Biomimetics and Biophotonics Research Group, Kings College London Dental Institute at Guy' s Hospital, King' s Health Partners, London (United Kingdom); Unit of Conservative Dentistry, King' s College London Dental Institute at Guy' s Hospital, King' s Health Partners, London (United Kingdom)

    2014-06-01

    The aims of this study were to assess: (a) the chemistry, morphology and bioactivity of bio-active glass (BAG) air-abrasive powder, (b) the effect of three air-abrasion operating parameters: air pressure, powder flow rate (PFR) and the abrasive powder itself, on the selective removal of resin composite and (c) the required “time taken”. BAG abrasive particles were characterised using scanning electron microscopy-energy dispersive X-ray spectrometry (SEM-EDX) and Fourier-transform infrared spectroscopy (FTIR). Standardised resin composite restorations created within an enamel analogue block (Macor™) in vitro, were removed using air-abrasion undersimulated clinical conditions. 90 standardised cavities were scanned before and after resin composite removal using laser profilometry and the volume of the resulting 3D images calculated. Multilevel linear model was used to identify the significant factors affecting Macor™ removal. BAG powder removed resin composite more selectively than conventional air-abrasion alumina powder using the same operating parameters (p < 0.001) and the effect of altering the unit's operating parameters was significant (p < 0.001). In conclusion, BAG powder is more efficient than alumina in the selective removal of resin composite particularly under specific operating parameters, and therefore may be recommended clinically as a method of preserving sound enamel structure when repairing and removing defective resin composite restorations.

  4. Atria selective prolongation by NIP-142, an antiarrhythmic agent, of refractory period and action potential duration in guinea pig myocardium.

    Science.gov (United States)

    Matsuda, Tomoyuki; Takeda, Kentaro; Ito, Mie; Yamagishi, Reiko; Tamura, Miku; Nakamura, Hideki; Tsuruoka, Noriko; Saito, Tomoaki; Masumiya, Haruko; Suzuki, Takeshi; Iida-Tanaka, Naoko; Itokawa-Matsuda, Maho; Yamashita, Toru; Tsuruzoe, Nobutomo; Tanaka, Hikaru; Shigenobu, Koki

    2005-05-01

    NIP-142 is a novel benzopyran compound that was shown to prolong the atrial effective refractory period and terminate experimental atrial fibrillation in the dog. In the present study, we examined the effects of NIP-142 on isolated guinea pig myocardium and on the G-protein-coupled inwardly rectifying potassium channel current (acetylcholine-activated potassium current; I(KACh)) expressed in Xenopus oocytes. NIP-142 (10 and 100 microM) concentration-dependently prolonged the refractory period and action potential duration in the atrium but not in the ventricle. E-4031 and 4-aminopyridine prolonged action potential duration in both left atrium and right ventricle. Prolongation by NIP-142 of the atrial action potential duration was observed at stimulation frequencies between 0.5 and 5 Hz. In contrast, the prolongation by E-4031 was not observed at higher frequencies. Tertiapin, a blocker of I(KACh), prolonged action potential duration in the atrium but not in the ventricle. NIP-142 completely reversed the carbachol-induced shortening of atrial action potential duration. NIP-142 (1 to 100 microM), as well as tertiapin (0.1 to 100 nM), concentration-dependently blocked I(KACh) expressed in Xenopus oocytes; the blockade by NIP-142 was not affected by membrane voltage. In conclusion, NIP-142 was shown to prolong atrial refractory period and action potential duration through blockade of I(KACh) which may possibly explain its previously described antiarrhythmic activity. NIP-142 has pharmacological properties that are different from classical class III antiarrhythmic agents such as atria specificity and lack of reverse frequency dependence, and thus appears promising for the treatment of supraventricular arrhythmia.

  5. Low- and intermediate level radioactive waste from Risoe, Denmark. Location studies for potential disposal areas. Report no. 1. Data, maps, models and methods used for selection of potential areas

    Energy Technology Data Exchange (ETDEWEB)

    Gravesen, P.; Nilsson, B.; Schack Pedersen, S.A.; Binderup, M.

    2011-07-01

    The low and intermediate level radioactive waste from Risoe (the nuclear reactor buildings plus different types of material from the research periods) and radioactive waste from hospitals and research institutes have to be stored in a final disposal in Denmark for at least 300 years. The Minister for Health and Prevention presented the background and decision plan for the Danish Parliament in January 2009. All political parties agreed on the plan. The investigation of geological deposits as potential waste disposals for high radioactive waste from nuclear power plants has earlier focused on deep seated salt deposits and basement rocks. Nevertheless, the Tertiary clays were mapped as well. In the present study, the salt diapirs and the salt deposits are not included. The present report briefly describes the existing data collections (including databases, maps and models), that are used during the work of selection of ca. 20 potentially suitable areas. Most of the information is stored in GEUS databases: Location of boreholes, borehole data, rock sediment and ground water compounds, maps, geophysical data and much more, but information is also collected from other institutions. The methods are described in more details (chapter 6) and this description is the direct background for the selection process, the characterisation of the 20 areas and for the final selection of the 2 or 3 most potential sites. (LN)

  6. Vertical Zonation of Horticultural Farming in the Alaknanda Basin of Garhwal Himalaya, India

    Institute of Scientific and Technical Information of China (English)

    Vishwambhar Prasad Sati

    2005-01-01

    Horticultural practice in the Himalayas has great importance not only for economic development but also for environmental restoration.In the entire Himalayan mountain system, from Jammu and Kashmir Himalaya to Assam Himalaya,the practice of horticulture is centuries old, which includes varieties of fruits along with availability of high quality and quantity. In terms of the Alaknanda Basin, which is centrally located in the Himalayan system, the practice of horticulture does not get commercial level; only it is cultivated domestically.The climatic conditions ranging from sub-tropical (low-lying river valleys) to alpine and frigid (highly elevated regions) are suited for varieties of fruit cultivation, yet the benefit of this could not be utilized by the residents who are working in the agricultural fields.Besides, less proportion of land is devoted for fruit cultivation along with domestic production of fruits. The varieties of fruit cultivated in the basin range from mango-guava-papaya, stone-net, citrus to apple at the different elevations. Along with the cultivated fruits, varieties of wild fruits are also found in the jungle. There are four climatic zones suitable for the production of various fruits as below:·Sub-tropical zone including the lower part of the Alaknanda, Pindar, Nandakini, and Mandakini rivers is suitable for mango, guava,and papaya;·Sub-temperate zone in the middle basin of the Alaknanda, Pindar, Nandakini and Mandakinirivers is a good place for citrus fruits,particularly orange and lemon;·Temperate zone occupying the Dauli, Vishnu Ganga, Upper Pinder, Nandakini and Mandakini rivers is highly productive for apple,nut and stone fruits;·Apline meadows in the highly elevated region are known as Bugyal famous for herb culture.Each of these zones has distinct physical features,environmental conditions and socio-economic identity for fruit cultivation. The present paper aims to discuss about the vertical zonation of the horticultural farming and

  7. Estimation of source parameters and scaling relations for moderate size earthquakes in North-West Himalaya

    Science.gov (United States)

    Kumar, Vikas; Kumar, Dinesh; Chopra, Sumer

    2016-10-01

    The scaling relation and self similarity of earthquake process have been investigated by estimating the source parameters of 34 moderate size earthquakes (mb 3.4-5.8) occurred in the NW Himalaya. The spectral analysis of body waves of 217 accelerograms recorded at 48 sites have been carried out using in the present analysis. The Brune's ω-2 model has been adopted for this purpose. The average ratio of the P-wave corner frequency, fc(P), to the S-wave corner frequency, fc(S), has been found to be 1.39 with fc(P) > fc(S) for 90% of the events analyzed here. This implies the shift in the corner frequency in agreement with many other similar studies done for different regions. The static stress drop values for all the events analyzed here lie in the range 10-100 bars average stress drop value of the order of 43 ± 19 bars for the region. This suggests the likely estimate of the dynamic stress drop, which is 2-3 times the static stress drop, is in the range of about 80-120 bars. This suggests the relatively high seismic hazard in the NW Himalaya as high frequency strong ground motions are governed by the stress drop. The estimated values of stress drop do not show significant variation with seismic moment for the range 5 × 1014-2 × 1017 N m. This observation along with the cube root scaling of corner frequencies suggests the self similarity of the moderate size earthquakes in the region. The scaling relation between seismic moment and corner frequency Mo fc3 = 3.47 ×1016Nm /s3 estimated in the present study can be utilized to estimate the source dimension given the seismic moment of the earthquake for the hazard assessment. The present study puts the constrains on the important parameters stress drop and source dimension required for the synthesis of strong ground motion from the future expected earthquakes in the region. Therefore, the present study is useful for the seismic hazard and risk related studies for NW Himalaya.

  8. The State of Food (InSecurity in the Trans-Himalaya, Upper-Mustang, Nepal

    Directory of Open Access Journals (Sweden)

    Rishikesh Pandey

    2016-10-01

    Full Text Available Food insecurity is a global issue, with higher prevalence of hunger in developing countries. Low crop yield and food production - due to difficult topography and traditional farming methods - combined with lower income; fluctuations in prices and supply, and low quality of food have been causing food insecurity in Nepal. This research examines food (insecurity situation in Upper-Mustang, Nepal. The results are derived from the data collected through face–to-face interviews with the heads of 66 households, in-depth interviews conducted with 22 key informants, and discussions with the group of local people in different (6 places. The household food system was studied from livelihood perspectives and food (insecurity was assessed in relation to self-sufficiency or production sufficiency, access, utilization, and stability of food. Households in the Trans-Himalaya acquire food from multiple sources such as farming and livestock ranching, buy food from the market, and also receive food aid for the sake of survival during the food crisis. Food security situation in terms of self-production in Upper-Mustang is at worst stage that many households are facing severe to chronic food insecurity. Studied households access marketed food, though the price they pay is very high. The worrisome issue is that there is no significant improvement in food security situation over time in the Trans-Himalaya. Study found that not the household size but dependency ratio in the household increases food insecurity. On the other hand, quality of farmland in terms of cropping intensity and availability of irrigation rather than the farm-plot size contribute for food security. The issue of food security is still a valid development policy goal for Nepal in general and for the Trans-Himalaya in particular. Accordingly, food security interventions are important. Yet, policy for interventions should look into all components of food systems, particularly providing irrigation

  9. Five years of ozonesoundings from the central Himalayas: role of dynamical processes and biomass burning

    Science.gov (United States)

    Naja, Manish; Bhardhwaj, Piyush; Lal, Shyam; Venkataramani, Sethuram; Kumar, Rajesh

    2016-04-01

    Higher water vapour, intense solar radiation and increasing levels of trace species over the tropical Asia are making this region more complex for understanding the physical, dynamical and chemical process over here. One of the most populated regions (The Indo-Gangetic Plain, IGP) of the world and a variety of anthropogenic and biogenic emission sources are also housing in the foothill of one of the pristine region, i.e. Himalaya. Uplifting and transport of polluted air-masses to the higher heights is a major concern in the South Asia. However, observations of vertical distribution of ozone, and other trace gases including water vapour, aerosols and meteorological parameters are very limited in South Asia. In view of this, an observational facility was setup at ARIES, Nainital (29.4N, 79.5E; 1950 m) in the central Himalayas. Regular, once in a week, balloon borne measurements of ozone, RH, temperature and GPS winds are being made since January 2011. Surface observations of different trace gases (Ozone, CO, NO, NOy, light NMHCs, SO2, CO2 and other GHGs) and aerosols are also being made at this site. Here, we present five years of ozonesoundings observations. A strong seasonal cycle in the lower tropospheric ozone with highest values during spring (~ 100 ppbv) and lowest during summer-monsoon (20-40 ppbv) is discerned. Elevated ozone levels (~120 ppbv) were observed in the middle-upper troposphere along with very high wind speed (~50 m/s) which indicates the role of dynamics in bringing ozone rich air from higher altitude. The signatures of ozone downward transport have also been noticed in TES water vapour and PV. In contrast, such influence is seen to be weaker in the eastern part of the Himalayas. A very clear enhancement (20-30 ppbv) in the lower tropospheric ozone is seen that is induced by the biomass burning. Further analysis of these observations with the help of air trajectories and satellite data will be presented.

  10. The Potential Impact of Banking Crises on Public Finances: An Assessment of Selected EU Countries Using SYMBOL

    OpenAIRE

    CAMPOLONGO Francesca; MARCHESI Massimo; DE LISA Riccardo

    2011-01-01

    This paper presents an application of the SYMBOL model, recently developed by the European Commission, in assessing the potential impact of banks’ crisis on public finance in four EU Member States. Results show that two Member States have a relatively high probability of being in the situation where government finances have to cover losses generated in the banking system

  11. Historical Perspective on How and Why Switchgrass was Selected as a "Model" High-Potential Energy Crop

    Energy Technology Data Exchange (ETDEWEB)

    Wright, Lynn L [ORNL

    2007-11-01

    A review of several publications of the Biofuels Feedstock Development Program, and final reports from the herbaceous crop screening trials suggests that there were several technical and non-technical factors that influenced the decision to focus on one herbaceous "model" crop species. The screening trials funded by the U.S. Department of Energy in the late 1980's to early 1990's assessed a wide range of about 34 species with trials being conducted on a wide range of soil types in 31 different sites spread over seven states in crop producing regions of the U.S. While several species, including sorghums, reed canarygrass and other crops, were identified as having merit for further development, the majority of institutions involved in the herbaceous species screening studies identified switchgrass as having high priority for further development. Six of the seven institutions included switchgrass among the species recommended for further development in their region and all institutions recommended that perennial grasses be given high research priority. Reasons for the selection of switchgrass included the demonstration of relatively high, reliable productivity across a wide geographical range, suitability for marginal quality land, low water and nutrient requirements, and positive environmental attributes. Economic and environmental assessments by Oak Ridge National Laboratory's Biofuels Feedstock Development Program staff together with the screening project results, and funding limitations lead to making the decision to further develop only switchgrass as a "model" or "prototype" species in about 1990. This paper describes the conditions under which the herbaceous species were screened, summarizes results from those trials, discusses the various factors which influenced the selection of switchgrass, and provides a brief evaluation of switchgrass with respect to criteria that should be considered when selecting and developing a crop for biofuels and

  12. Assessing the potential for an ongoing arms race within and between the sexes: selection and heritable variation.

    Science.gov (United States)

    Friberg, Urban; Lew, Timothy A; Byrne, Phillip G; Rice, William R

    2005-07-01

    In promiscuous species, sexual selection generates two opposing male traits: offense (acquiring new mates and supplanting stored sperm) and defense (enforcing fidelity on one's mates and preventing sperm displacement when this fails). Coevolution between these traits requires both additive genetic variation and associated natural selection. Previous work with Drosophila melanogaster found autosomal genetic variation for these traits among inbred lines from a mixture of populations, but only nonheritable genetic variation was found within a single outbred population. These results do not support ongoing antagonistic coevolution between offense and defense, nor between either of these male traits and female reproductive characters. Here we use a new method (hemiclonal analysis) to study genomewide genetic variation in a large outbred laboratory population of D. melanogaster. Hemiclonal analysis estimates the additive genetic variation among random, genomewide haplotypes taken from a large, outbred, locally adapted laboratory population and determines the direction of the selection gradient on this variation. In contrast to earlier studies, we found low but biologically significant heritable variation for defensive and offensive offspring production as well as all their components (P1, fidelity, P2, and remating). Genetic correlations between these traits were substantially different from those reported for inbred lines. A positive genetic correlation was found between defense and offense, demonstrating that some shared genes influence both traits. In addition to this common variation, evidence for unique genetic variation for each trait was also found, supporting an ongoing coevolutionary arms race between defense and offense. Reproductive conflict between males can strongly influence female fitness. Correspondingly, we found genetic variation in both defense and offense that affected female fitness. No evidence was found for intersexual conflict in the context of

  13. Identification of Lactic Acid Bacteria in Fruit Pulp Processing Byproducts and Potential Probiotic Properties of Selected Lactobacillus Strains

    Science.gov (United States)

    Garcia, Estefânia F.; Luciano, Winnie A.; Xavier, Danilo E.; da Costa, Whyara C. A.; de Sousa Oliveira, Kleber; Franco, Octávio L.; de Morais Júnior, Marcos A.; Lucena, Brígida T. L.; Picão, Renata C.; Magnani, Marciane; Saarela, Maria; de Souza, Evandro L.

    2016-01-01

    This study aimed to identify lactic acid bacteria (LAB) in byproducts of fruit (Malpighia glabra L., Mangifera indica L., Annona muricata L., and Fragaria vesca L.) pulp processing. Fifty strains of LAB were identified using matrix-assisted laser desorption/ionization–time of flight mass spectrometry (MALDI-TOF MS) and 16S rRNA gene sequence (16S rRNA) analysis. Species belonging to Lactobacillus genus were the predominant LAB in all fruit pulp processing byproducts. The average congruency between the MALDI-TOF MS and 16S rRNA in LAB species identification reached 86%. Isolates of L. plantarum, L. brevis, L. pentosus, L. lactis and L. mesenteroides were identified with 100% congruency. MALDI-TOF MS and 16S rRNA analysis presented 86 and 100% efficiency of LAB species identification, respectively. Further, five selected Lactobacillus strains (L. brevis 59, L. pentosus 129, L. paracasei 108, L. plantarum 49, and L. fermentum 111) were evaluated for desirable probiotic-related properties and growth behavior on two different cultivation media. The exposure to pH 2.0 sharply decreased the counts of the different Lactobacillus strains after a 1 or 2 h incubation, while varied decreases were noted after 3 h of exposure to pH 3.0. Overall, the exposure to pH 5.0 and to bile salts (0.15, 0.30, and 1.00%) did not decrease the counts of the Lactobacillus strains. All tested Lactobacillus strains presented inhibitory activity against Staphylococcus aureus, Salmonella Typhimurium, Salmonella Enteritidis, Listeria monocytogenes and Escherichia coli, and presented variable susceptibility to different antibiotics. The selected Lactobacillus strains presented satisfactory and reproducible growth behavior. In conclusion, MALDI-TOF MS and 16S rRNA analysis revealed high efficiency and congruency for LAB species identification, and the selected Lactobacillus strains may be candidates for further investigation of novel probiotic strains. PMID:27625647

  14. Identification of lactic acid bacteria in fruit pulp processing byproducts and potential probiotic properties of selected Lactobacillus strains

    Directory of Open Access Journals (Sweden)

    Estefânia Garcia

    2016-08-01

    Full Text Available This study aimed to identify lactic acid bacteria (LAB in byproducts of fruit (Malpighia glabra L., Mangifera indica L., Annona muricata L. and Fragaria vesca L. pulp processing. Fifty strains of LAB were identified using matrix-assisted laser desorption/ionization–time of flight mass spectrometry (MALDI-TOF MS and 16S rRNA gene sequence (16S rRNA analysis. Species belonging to Lactobacillus genus were the predominant LAB in all fruit pulp processing byproducts. The average congruency between the MALDI-TOF MS and 16S rRNA in LAB species identification reached 86%. Isolates of L. plantarum, L. brevis, L. pentosus, L. lactis and L. mesenteroides were identified with 100% congruency. MALDI-TOF MS and 16S rRNA analysis presented 86% and 100% efficiency of LAB species identification, respectively. Further, five selected Lactobacillus strains (L. brevis 59, L. pentosus 129, L. paracasei 108, L. plantarum 49 and L. fermentum 111 were evaluated for desirable probiotic-related properties and growth behavior on two different cultivation media. The exposure to pH 2.0 sharply decreased the counts of the different Lactobacillus strains after a 1 or 2 h incubation, while varied decreases were noted after 3 h of exposure to pH 3.0. Overall, the exposure to pH 5.0 and to bile salts (0.15, 0.30 and 1.00% did not decrease the counts of the Lactobacillus strains. All tested Lactobacillus strains presented inhibitory activity against Staphylococcus aureus, Salmonella Typhimurium, Salmonella Enteritidis, Listeria monocytogenes and Escherichia coli, and presented variable susceptibility to different antibiotics. The selected Lactobacillus strains presented satisfactory and reproducible growth behavior. In conclusion, MALDI-TOF MS and 16S rRNA analysis revealed high efficiency and congruency for LAB species identification, and the selected Lactobacillus strains may be candidates for further investigation of novel probiotic strains.

  15. Identification of Lactic Acid Bacteria in Fruit Pulp Processing Byproducts and Potential Probiotic Properties of Selected Lactobacillus Strains.

    Science.gov (United States)

    Garcia, Estefânia F; Luciano, Winnie A; Xavier, Danilo E; da Costa, Whyara C A; de Sousa Oliveira, Kleber; Franco, Octávio L; de Morais Júnior, Marcos A; Lucena, Brígida T L; Picão, Renata C; Magnani, Marciane; Saarela, Maria; de Souza, Evandro L

    2016-01-01

    This study aimed to identify lactic acid bacteria (LAB) in byproducts of fruit (Malpighia glabra L., Mangifera indica L., Annona muricata L., and Fragaria vesca L.) pulp processing. Fifty strains of LAB were identified using matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) and 16S rRNA gene sequence (16S rRNA) analysis. Species belonging to Lactobacillus genus were the predominant LAB in all fruit pulp processing byproducts. The average congruency between the MALDI-TOF MS and 16S rRNA in LAB species identification reached 86%. Isolates of L. plantarum, L. brevis, L. pentosus, L. lactis and L. mesenteroides were identified with 100% congruency. MALDI-TOF MS and 16S rRNA analysis presented 86 and 100% efficiency of LAB species identification, respectively. Further, five selected Lactobacillus strains (L. brevis 59, L. pentosus 129, L. paracasei 108, L. plantarum 49, and L. fermentum 111) were evaluated for desirable probiotic-related properties and growth behavior on two different cultivation media. The exposure to pH 2.0 sharply decreased the counts of the different Lactobacillus strains after a 1 or 2 h incubation, while varied decreases were noted after 3 h of exposure to pH 3.0. Overall, the exposure to pH 5.0 and to bile salts (0.15, 0.30, and 1.00%) did not decrease the counts of the Lactobacillus strains. All tested Lactobacillus strains presented inhibitory activity against Staphylococcus aureus, Salmonella Typhimurium, Salmonella Enteritidis, Listeria monocytogenes and Escherichia coli, and presented variable susceptibility to different antibiotics. The selected Lactobacillus strains presented satisfactory and reproducible growth behavior. In conclusion, MALDI-TOF MS and 16S rRNA analysis revealed high efficiency and congruency for LAB species identification, and the selected Lactobacillus strains may be candidates for further investigation of novel probiotic strains.

  16. A potential new selection criterion for breeding winter barley optimal protein and amino acid profiles for liquid pig feed

    DEFF Research Database (Denmark)

    Christensen, Jesper Bjerg; Blaabjerg, Karoline; Poulsen, Hanne Damgaard

    The hypothesis is that cereal proteases in liquid feed degrade and convert water insoluble storage protein into water soluble protein, which may improve the digestibility of protein in pigs compared with dry feeding. Protein utilization is increased by matching the amino acid (AAs) content...... concentration was analysed in the supernatant after centrifugation. After 15 min., app. 16% of the total protein was soluble and until 8 hours an increase of 5% units was observed. However, from 8 to 48 hours it increased with 10% units for some cultivars. Based on these analyses, cultivars were selected...

  17. Bio-active glass air-abrasion has the potential to remove resin composite restorative material selectively

    Science.gov (United States)

    Milly, Hussam; Andiappan, Manoharan; Thompson, Ian; Banerjee, Avijit

    2014-06-01

    The aims of this study were to assess: (a) the chemistry, morphology and bioactivity of bio-active glass (BAG) air-abrasive powder, (b) the effect of three air-abrasion operating parameters: air pressure, powder flow rate (PFR) and the abrasive powder itself, on the selective removal of resin composite and (c) the required “time taken”. BAG abrasive particles were characterised using scanning electron microscopy-energy dispersive X-ray spectrometry (SEM-EDX) and Fourier-transform infrared spectroscopy (FTIR). Standardised resin composite restorations created within an enamel analogue block (Macor™) in vitro, were removed using air-abrasion undersimulated clinical conditions. 90 standardised cavities were scanned before and after resin composite removal using laser profilometry and the volume of the resulting 3D images calculated. Multilevel linear model was used to identify the significant factors affecting Macor™ removal. BAG powder removed resin composite more selectively than conventional air-abrasion alumina powder using the same operating parameters (p resin composite particularly under specific operating parameters, and therefore may be recommended clinically as a method of preserving sound enamel structure when repairing and removing defective resin composite restorations.

  18. Assessment of the in Vitro Antiprotozoal and Cytotoxic Potential of 20 Selected Medicinal Plants from the Island of Soqotra

    Directory of Open Access Journals (Sweden)

    Louis Maes

    2012-12-01

    Full Text Available Malaria, leishmaniasis and human African trypanosomiasis continue to be major public health problems in need of new and more effective drugs. The aim of this study was to evaluate in vitro antiprotozoal activity of twenty endemic medicinal plants collected from the island of Soqotra in the Indian Ocean. The plant materials were extracted with methanol and tested for antiplasmodial activity against erythrocytic schizonts of Plasmodium falciparum, for antileishmanial activity against intracellular amastigotes of Leishmania infantum and for antitrypanosomal activity against intracellular amastigotes of Trypanosoma cruzi and free trypomastigotes of T. brucei. To assess selectivity, cytotoxicity was determined against MRC-5 fibroblasts. Selective activity was obtained for Punica protopunica against Plasmodium (IC50 2.2 µg/mL while Eureiandra balfourii and Hypoestes pubescens displayed activity against the three kinetoplastid parasites (IC50 < 10 µg/mL. Acridocarpus socotranus showed activity against T. brucei and T. cruzi (IC50 3.5 and 8.4 µg/mL. Ballochia atrovirgata, Dendrosicycos socotrana, Dracaena cinnabari and Euphorbia socotrana displayed non-specific inhibition of the parasites related to high cytotoxicity.

  19. Dicotyledon Weed Quantification Algorithm for Selective Herbicide Application in Maize Crops: Statistical Evaluation of the Potential Herbicide Savings

    DEFF Research Database (Denmark)

    Stigaard Laursen, Morten; Jørgensen, Rasmus Nyholm; Midtiby, Henrik Skov;

    on the initial weed coverage. However, additional field trials covering more seasons and locations are needed to verify the generalisation of these results. There is a potential for further herbicide savings as the time interval between the first and second spraying session was not long enough for the weeds......This work contributes a statistical model and simulation framework yielding the best estimate possible for the potential herbicide reduction when using the MoDiCoVi algorithm all the while requiring an efficacy comparable to conventional spraying. In June 2013 a maize field located in Denmark were...... seeded. The field was divided into parcels which were assigned to one of two main groups: 1) Control, consisting of subgroups of no spray and full dose spray; 2) MoDiCoVi algorithm subdivided into five different leaf cover thresholds for spray activation. Also approximately 25% of the parcels were seeded...

  20. Self-consistent many-electron theory of electron work functions and surface potential characteristics for selected metals

    Science.gov (United States)

    Smith, J. R.

    1969-01-01

    Electron work functions, surface potentials, and electron number density distributions and electric fields in the surface region of 26 metals were calculated from first principles within the free electron model. Calculation proceeded from an expression of the total energy as a functional of the electron number density, including exchange and correlation energies, as well as a first inhomogeneity term. The self-consistent solution was obtained via a variational procedure. Surface barriers were due principally to many-body effects; dipole barriers were small only for some alkali metals, becoming quite large for the transition metals. Surface energies were inadequately described by this model, which neglects atomistic effects. Reasonable results were obtained for electron work functions and surface potential characteristics, maximum electron densities varying by a factor of over 60.

  1. Determination of trace metals, moisture, pH and assessment of potential toxicity of selected smokeless tobacco products

    Directory of Open Access Journals (Sweden)

    V Prabhakar

    2013-01-01

    Full Text Available The characterization and classification of smokeless tobacco products has been a continuously evolving process. This is based on a number of different parameters like nicotine content, moisture content, amount of heavy metals, pH, and in vitro cytotoxicity assays. Their contexts often vary between countries, research institutions, and legal requirements. The categorisation of these products is quite challenging due to the diffused sample sizes, diverse array of branded products on offer, and the absence of a centralized manufacturing facility. This study aims at a systematic classification of 10 smokeless tobacco product samples from the retail market based on their potential toxicity upon long-term use. The estimation of potential toxicity follows a well-established method that employs the concentration of toxic metals in the different samples. The potential toxicity as well as heavy metal concentrations of the smokeless tobacco products analysed was found to be much higher than acceptable limits. For instance, the levels of lead, cadmium, copper and zinc of 2.5, 1, 4 and 23 ppm, respectively, are well above their recommended limits. The results from the study indicate that chronic use of smokeless tobacco products is a significant health risk, especially in the vulnerable population. Further studies of this nature will help establish a toxicological fingerprint on the diverse class of products that floods the market now.

  2. Auditory attention in childhood and adolescence: An event-related potential study of spatial selective attention to one of two simultaneous stories.

    Science.gov (United States)

    Karns, Christina M; Isbell, Elif; Giuliano, Ryan J; Neville, Helen J

    2015-06-01

    Auditory selective attention is a critical skill for goal-directed behavior, especially where noisy distractions may impede focusing attention. To better understand the developmental trajectory of auditory spatial selective attention in an acoustically complex environment, in the current study we measured auditory event-related potentials (ERPs) across five age groups: 3-5 years; 10 years; 13 years; 16 years; and young adults. Using a naturalistic dichotic listening paradigm, we characterized the ERP morphology for nonlinguistic and linguistic auditory probes embedded in attended and unattended stories. We documented robust maturational changes in auditory evoked potentials that were specific to the types of probes. Furthermore, we found a remarkable interplay between age and attention-modulation of auditory evoked potentials in terms of morphology and latency from the early years of childhood through young adulthood. The results are consistent with the view that attention can operate across age groups by modulating the amplitude of maturing auditory early-latency evoked potentials or by invoking later endogenous attention processes. Development of these processes is not uniform for probes with different acoustic properties within our acoustically dense speech-based dichotic listening task. In light of the developmental differences we demonstrate, researchers conducting future attention studies of children and adolescents should be wary of combining analyses across diverse ages.

  3. Effect of process parameters upon the dopamine and lipid peroxidation activity of selected MIG welding fumes as a marker of potential neurotoxicity.

    Science.gov (United States)

    Hudson, N J; Evans, A T; Yeung, C K; Hewitt, P J

    2001-04-01

    There is growing concern over the neurotoxic effects of chronic occupational exposure to metal fume produced by welding. Elevated iron and manganese levels in the brain have been linked to an increase in lipid peroxidation, dopamine depletion and predisposition to the development of a Parkinson's type condition in advanced cases. Chemical and toxicological analysis of selected welding fumes, generated by model processes, were used in order to evaluate their potential to release solutes that promote oxidation of dopamine and peroxidation of brain lipids in cell free assays. This study compared the effect of shield gas, electrode type and voltage/currect upon the dopamine and brain lipid peroxidation potential of selected welding fume, obtained from metal inert gas (MIG) welding systems. Overall, fume extracts were found to enhance dopamine oxidation and inhibit lipid peroxidation. Significant differences were also found in the oxidising potential of fume generated under differing process conditions; it may therefore be possible to determine the potential neurotoxicity of fumes using this system.

  4. Auditory attention in childhood and adolescence: An event-related potential study of spatial selective attention to one of two simultaneous stories

    Directory of Open Access Journals (Sweden)

    Christina M. Karns

    2015-06-01

    Full Text Available Auditory selective attention is a critical skill for goal-directed behavior, especially where noisy distractions may impede focusing attention. To better understand the developmental trajectory of auditory spatial selective attention in an acoustically complex environment, in the current study we measured auditory event-related potentials (ERPs across five age groups: 3–5 years; 10 years; 13 years; 16 years; and young adults. Using a naturalistic dichotic listening paradigm, we characterized the ERP morphology for nonlinguistic and linguistic auditory probes embedded in attended and unattended stories. We documented robust maturational changes in auditory evoked potentials that were specific to the types of probes. Furthermore, we found a remarkable interplay between age and attention-modulation of auditory evoked potentials in terms of morphology and latency from the early years of childhood through young adulthood. The results are consistent with the view that attention can operate across age groups by modulating the amplitude of maturing auditory early-latency evoked potentials or by invoking later endogenous attention processes. Development of these processes is not uniform for probes with different acoustic properties within our acoustically dense speech-based dichotic listening task. In light of the developmental differences we demonstrate, researchers conducting future attention studies of children and adolescents should be wary of combining analyses across diverse ages.

  5. Catastrophic mass movement of 1998 monsoons at Malpa in Kali Valley, Kumaun Himalaya (India)

    Science.gov (United States)

    Paul, S. K.; Bartarya, S. K.; Rautela, Piyoosh; Mahajan, A. K.

    2000-11-01

    A devastating landslide on 18 August 1998 near Malpa Village in Kali Valley of Higher Kumaun Himalaya killed 221 persons. The landslide was a complex rock fall-debris flow. The mass movement generated around one million cubic metres of debris and partially blocked the Kali River, Malpa Gad (a tributary of Kali) being blocked completely. The rock mass failed primarily due to the near vertical slopes hanging over the valley along joints, the formation of structural wedges along the free face, the sheared rock mass due to the close proximity of major tectonic planes, and the enhanced pore-water pressure due to prolonged heavy precipitation in the preceding days. The mesoscopic shear zone, exhibiting ramp and flat structure in quartzites, shows a southward thrust movement that might have generated shear stress in the rocks. The slide clearly demonstrates the distressed state of the rock mass in the Himalayan region due to the ongoing northward drift of the Indian plate.

  6. The Himalayas and a Survey of Determining the Height of Mt. Everest

    Directory of Open Access Journals (Sweden)

    Miljenko Solarić

    2010-12-01

    Full Text Available The introduction to this article describes the Himalayan mountain range, while the next chapter outlines its formation. The article then goes on to describe the early use of trigonometric networks in Europe and India, and the important achievements of Sir George Everest. When his successor, A. S. Waugh, extended the trigonometric network to the foot of the Himalayas, he determined the height of the highest peak of Mt. Everest trigonometrically, by measuring vertical angles only in the direction of Mt. Everest. Later, it became possible to determine the height of the highest peak in the world more precisely, using modern surveying means. The peak was named Mt. Everest in 1865, at the proposal of A. S. Waugh. It is known by other names by the indigenousl populations in China and Nepal. Finally, the earliest attempts to climb Mt. Everest are described.

  7. Underplating in the Himalaya-Tibet collision zone revealed by the Hi-CLIMB experiment.

    Science.gov (United States)

    Nábelek, John; Hetényi, György; Vergne, Jérôme; Sapkota, Soma; Kafle, Basant; Jiang, Mei; Su, Heping; Chen, John; Huang, Bor-Shouh

    2009-09-11

    We studied the formation of the Himalayan mountain range and the Tibetan Plateau by investigating their lithospheric structure. Using an 800-kilometer-long, densely spaced seismic array, we have constructed an image of the crust and upper mantle beneath the Himalayas and the southern Tibetan Plateau. The image reveals in a continuous fashion the Main Himalayan thrust fault as it extends from a shallow depth under Nepal to the mid-crust under southern Tibet. Indian crust can be traced to 31 degrees N. The crust/mantle interface beneath Tibet is anisotropic, indicating shearing during its formation. The dipping mantle fabric suggests that the Indian mantle is subducting in a diffuse fashion along several evolving subparallel structures.

  8. 10-year record of atmospheric composition in the high Himalayas: source, transport and impact

    Science.gov (United States)

    Bonasoni, Paolo; Laj, Paolo; Marinoni, Angela; Cristofanelli, Paolo; Maione, Michela; Putero, Davide; Calzolari, Francescopiero; Decesari, Stefano; Facchini, Maria Cristina; Fuzzi, Sandro; Gobbi, Gianpaolo; Sellegri, Karine; Verza, Gianpietro; Vuillermoz, Elisa; Arduini, Jgor

    2016-04-01

    South Asia represents a global "hot-spot" for air-quality and climate impacts. Since the end of the 20th Century, field experiments and satellite observations identified a thick layer of atmospheric pollutants extending from the Indian Ocean up to the atmosphere of the Himalayas. Since large amount of short-lived climate pollutants (SLCPs) - like atmospheric aerosol (in particular, the light-absorbing aerosol) and ozone - characterize this region, severe implications were recognized for population health, ecosystem integrity as well as regional climate impacts, especially for what concerns hydrological cycle, monsoon regimes and cryosphere. Since 2006, the Nepal Climate Observatory - Pyramid (NCO-P, 27.95N, 86.82 E, 5079 m a.s.l.), a global station of the WMO/GAW programme has been active in the eastern Nepal Himalaya, not far from the Mt. Everest. NCO-P is located away from large direct anthropogenic pollution sources. The closest major urban area is Kathmandu (200 km south-west from the measurement site). As being located along the Khumbu valley, the observations are representative of synoptic-scale and mountain thermal circulation, providing direct information about the vertical transport of pollutants/climate-altering compounds to the Himalayas and to the free troposphere. In the framework of international programmes (GAW/WMO, UNEP-ABC, AERONET) the following continuous measurement programmes have been carried out at NCO-P: surface ozone, aerosol size distribution (from 10 nm to 25 micron), total particle number, aerosol scattering and absorption coefficients, equivalent BC, PM1-PM10, AOD by sun-photometry, global solar radiation (SW and LW), meteorology. Long-term sampling programmes for the off-line determination of halogenated gases and aerosol chemistry have been also activated. The atmospheric observation records at NCO-P, now representing the longest time series available for the high Himalayas, provided the first direct evidences about the systematic

  9. Paleoseismic evidence of a giant medieval earthquake in the eastern Himalaya

    Science.gov (United States)

    Mishra, Rajeeb Lochan; Singh, I.; Pandey, A.; Rao, P. S.; Sahoo, H. K.; Jayangondaperumal, R.

    2016-06-01

    We present here the results of a paleoseismic investigation carried across a ~10 m high fault scarp at Panijhora village, West Bengal in northeastern India. Accelerator Mass Spectrometer analyzed 14C radiocarbon age constraints from six detrital charcoal samples ranging between 1688 B.C. and A.D. 1152 are consistent with the great medieval earthquake of A.D. 1255 that is interpreted to have produced a minimum observed fault slip of ~5 m in the trench exposure. Recalibration of radiocarbon ages from previous studies at Harmutty, Nameri, and Marha in the eastern Himalaya using Bayesian statistical analyses further substantiates the possibility that the A.D. 1255 earthquake might have ruptured the Himalayan front over a length of ~800 km from ~85.87° to 93.76°E longitudes.

  10. Repeated catastrophic valley infill following medieval earthquakes in the Nepal Himalaya.

    Science.gov (United States)

    Schwanghart, Wolfgang; Bernhardt, Anne; Stolle, Amelie; Hoelzmann, Philipp; Adhikari, Basanta R; Andermann, Christoff; Tofelde, Stefanie; Merchel, Silke; Rugel, Georg; Fort, Monique; Korup, Oliver

    2016-01-08

    Geomorphic footprints of past large Himalayan earthquakes are elusive, although they are urgently needed for gauging and predicting recovery times of seismically perturbed mountain landscapes. We present evidence of catastrophic valley infill following at least three medieval earthquakes in the Nepal Himalaya. Radiocarbon dates from peat beds, plant macrofossils, and humic silts in fine-grained tributary sediments near Pokhara, Nepal's second-largest city, match the timing of nearby M > 8 earthquakes in ~1100, 1255, and 1344 C.E. The upstream dip of tributary valley fills and x-ray fluorescence spectrometry of their provenance rule out local sources. Instead, geomorphic and sedimentary evidence is consistent with catastrophic fluvial aggradation and debris flows that had plugged several tributaries with tens of meters of calcareous sediment from a Higher Himalayan source >60 kilometers away.

  11. Middle Miocene pedological record of monsoonal climate from NW Himalaya (Jammu & Kashmir State), India

    Science.gov (United States)

    Ganjoo, R. K.; Shaker, Som

    2007-03-01

    The Lower Siwalik Subgroup represented by the Dodenal (Kamlial Formation) and Ramnagar Members (Chinji Formation) is well exposed at Ramnagar, District Udhampur, Jammu & Kashmir State. The Ramnagar Member consists of an alternating sequence of silt and mudstone formed under crevasse-splay and flood-plain environments of deposition. Argillisol and gleysol soils are developed on the Ramnagar Member deposits. Argillisols formed under well-drained conditions at high levels, whereas gleysols formed under poorly drained conditions at low levels of the palaeo-landscape. Geochemical and micromorphological studies of the Ramnagar Member palaeosols suggest formation under wet and humid climatic conditions. Early uplift of the Tibetan Plateau/Himalaya resulted in a contemporaneous change in precipitation and monsoonal climate conditions within the Indian region beginning in Middle Miocene.

  12. Glacier variations and climate warming and drying in the central Himalayas

    Institute of Scientific and Technical Information of China (English)

    REN Jiawen; QIN Dahe; KANG Shichang; HOU Shugui; PU Jianchen; JING Zhefan

    2004-01-01

    Repeat measurements of glacier terminus positions show that glaciers in the central Himalayas have been in a continuous retreat situation in the past decades. The average retreat rate is 5.5-8.7 m/a in Mt. Qomolangma (Everest) since the 1960s and 6.4 m/a in Mt. Xixiabangma since the 1980s. In recent years, the retreat rate is increasing. Ice core studies revealed that the accumulation rate of glaciers has a fluctuating decrease trend in the last century with a rapid decrease in the 1960s and a relatively steady low value afterwards. Meteorological station record indicates that the annual mean temperature has a slow increase trend but summer temperature had a larger increase in the past 30 a. All these suggest that the glacier retreat results from precipitation decrease in combination with temperature increase, and hence glacier shrinkage in this region will speed up if the climatic warming and drying continues.

  13. Modeling the Current and Future Distribution of Treeline Species in the Nepal Himalaya

    Science.gov (United States)

    Chhetri, P. K.; Cairns, D. M.

    2015-12-01

    Knowledge of the current distribution of treeline species is important for predicting their future distribution in the landscape. Many studies have indicated that treeline will advance with climate change. Treeline advance will result in a loss of alpine biodiversity because the advancing treeline will fragment alpine ecosystems. A species distribution modeling approach using predicted climate data can increase our understanding of how treeline species will expand their range in the future. We used the Maxent model to predict the current and future distributions of three dominant treeline species, Abies spectabilis, Betula utilis, and Pinus wallichiana, of the Nepal Himalaya. The Maxent model predicted that the distribution of treeline species will change significantly under future climate change scenarios. The range of these treeline species will expand northward or upslope in response to future climate change. The model also indicated that temperature-related climatic variables are the most important determinants of the distribution of treeline species.

  14. The effects of disturbance on forest structure and diversity at different altitudes in Garhwal Himalaya

    Institute of Scientific and Technical Information of China (English)

    Munesh KUMA; Chandra Mohan SHARMA; Govind Singh RAJWAR

    2009-01-01

    The effects of disturbance on forest structure and diversity along an altitudinal gradient in the temperate, sub-tropical, and tropical regions of Garhwal Himalaya were assessed. Each region was further categorized into undisturbed (UD), mildly disturbed (MD), and highly disturbed (HD) sites on the basis of magnitude of disturbance in these forests. On UD sites of temperate, sub-tropical and tropical regions, Quercus leucotrichophora, Anogeissus latifolia and Holoptelea integrifolia were the dominant tree species respectively. The highest values of tree density (1028 ind*hm-2) and total basal cover at breast height (31.70 m2 *hm-2) were recorded for UD site of temperate region, whereas maximum species diversity (3.128) and equitability (14.09) values were observed for HD site of tropical region. The structure and composition of the forests were greatly affected by the degree of disturbance.

  15. Radon measurements in soil and water and its relation with geology, Garhwal Himalaya, India

    Energy Technology Data Exchange (ETDEWEB)

    Choubey, V.M. [Wadia Institute of Himalayan Geology, Dehra Dun (India)

    1998-12-31

    Radon concentrations were measured in soil and spring water in the Garhwal Himalaya using radon emanometer. The measurements were made in the Berinag, Bhatwari and Munsiari Formations. The main rock types in the area are sheared granitic gneiss, porphyritic gneiss, chlorite schist, mica schist, mylonite, slate, phyllite, quartzite and metabasic. The radon concentrations were found to vary from 1.2 kBq/m{sup 3} to 56.5 kBq/m{sup 3} in soil and 0.4 Bq/l to 887 Bq/l in water. The results suggest that the radon emanation is controlled not only by uranium content of the rock and soil but also by structural zones (thrust, fault, etc.) which help in the easy migration of radon from the deeper parts of the earth crust. (author)

  16. Variations of the crustal thickness in Nepal Himalayas based on tomographic inversion of regional earthquake data

    Directory of Open Access Journals (Sweden)

    I. Koulakov

    2014-10-01

    Full Text Available We estimate variations of the crustal thickness beneath the Nepal Himalayas based on tomographic inversion of regional earthquake data. We have obtained a low-velocity anomaly in the upper part of the model down to depths of 40 to 80 km and proposed that the lower limit of this anomaly represents variations of the Moho depth. This statement was supported by results of synthetic modeling. The obtained variations of crustal thickness match fairly well with the free-air gravity anomalies: thinner crust patterns correspond to lower gravity values and vice versa. There is also some correlation with magnetic field: higher magnetic values correspond to the major areas of thicker crust. We propose that elevated magnetic values can be associated with more rigid segments of the incoming Indian crust which cause more compression in the thrust zone and leads to stronger crustal thickening.

  17. Crustal Decoupling in Collisional Orogenesis: Examples from the East Greenland Caledonides and Himalaya

    Science.gov (United States)

    Hodges, K. V.

    2016-06-01

    Mature orogenic systems built by continent-continent collision feature orogenic plateaus flanked by accretionary wedges. Thermal-mechanical models of these systems predict the development of a thermally weakened orogenic infrastructure that is capable of lateral flow toward the orogenic foreland. Such flow, if it occurs, strongly influences the evolutionary pathway of a wedge. Although the architecture of a wedge features numerous large-displacement faults, three are preeminent in mature orogens: one that marks the base of the wedge and two others that mark the base and top, respectively, of the weakened infrastructure. These structures represent major decoupling horizons separating domains with distinctive deformational and thermal histories. Reviews of the geology of orogenic wedges in two mature orogenic systems—the Cenozoic Himalaya and the Paleozoic East Greenland Caledonides—show how this simple conceptual model provides a valuable context for studies of how collisional orogenic systems develop and how they interact with the surrounding lithosphere.

  18. Prenanthes violaefolia Decne. (Asteraceae)-a new report from Kashmir Himalaya, India

    Institute of Scientific and Technical Information of China (English)

    Parvaiz Ahmad Lone; Ajay Kumar Bhardwaj; Kunwar Wajahat Shah

    2015-01-01

    Objective:To enumerate the diversity of important medicinal plants used traditionally by the local populace in biodiversity rich and temperate Himalayan ranges of Bandipora district, Jammu and Kashmir, India. Methods:Methods used to explore the plants with medicinal value and to record associated ethnomedicinal knowledge included semi-structured interviews, focus group discussions and walk-in-the-woods with local knowledgeable persons, traditional practitioners called“Bhoeris”and tribals (Gujjars and Bakkerwals). Results:During plant exploration in this floristically rich Himalayan region, a very interesting and less-known species of the genus Prenanthes L., (Asteraceae) was recorded. On examination, the species was identified as Prenanthes violaefolia Decne., which represents a first report from Kashmir Himalaya, India. Conclusions: Prenanthes violaefolia could serve as an important source of new potent compounds provided that it is subjected to thorough phytochemical and pharmacological investigations.

  19. Prenanthes violaefolia Decne.(Asteraceae)-a new report from Kashmir Himalaya, India

    Institute of Scientific and Technical Information of China (English)

    Parvaiz; Ahmad; Lone; Ajay; Kumar; Bhardwaj; Kunwar; Wajahat; Shah

    2015-01-01

    Objective: To enumerate the diversity of important medicinal plants used traditionally by the local populace in biodiversity rich and temperate Himalayan ranges of Bandipora district, Jammu and Kashmir, India. Methods: Methods used to explore the plants with medicinal value and to record associated ethnomedicinal knowledge included semi-structured interviews, focus group discussions and walk-in-the-woods with local knowledgeable persons, traditional practitioners called "Bhoeris" and tribals(Gujjars and Bakkerwals). Results: During plant exploration in this floristically rich Himalayan region, a very interesting and less-known species of the genus Prenanthes L.,(Asteraceae) was recorded. On examination, the species was identified as Prenanthes violaefolia Decne., which represents a first report from Kashmir Himalaya, India. Conclusions: Prenanthes violaefolia could serve as an important source of new potent compounds provided that it is subjected to thorough phytochemical and pharmacological investigations.

  20. Ethnomycological studies of some wild medicinal and edible mushrooms in the Kashmir Himalayas (India).

    Science.gov (United States)

    Pala, Shauket Ahmed; Wani, Abdul Hamid; Bhat, Mohmmad Yaqoub

    2013-01-01

    The medicinal use of mushrooms has a very long tradition in Asian countries because of their use as a valuable tonic, food, and in herbal medicines. A study was carried out to document the indigenous uses of various mushrooms growing in the Kashmir Himalayas. After consulting local herbal healers (Hakims) and people from tribal communities inhabiting inaccessible hinterlands of the region regarding the use of mushrooms growing in their locality, it was found that 35 species of mushrooms belonging to different ecological and taxonomical groups were used for their nutritional and medicinal values. These mushrooms were used for their activities against a broad spectrum of diseases, ranging from simple skin diseases to present-day complex diseases such as diabetes and tumors.

  1. Similarities and differences of aerosol optical properties between southern and northern slopes of the Himalayas

    Directory of Open Access Journals (Sweden)

    C. Xu

    2013-08-01

    Full Text Available The Himalayas is located at the southern edge of the Tibetan Plateau, and it acts as a natural barrier for the transport of atmospheric aerosols, e.g. from the polluted regions of South Asia to the main body of the Tibetan Plateau. In this study, we investigate the seasonal and diurnal variations of aerosol optical properties measured at the three Aerosol Robotic Network (AERONET sites over the southern (Pokhara station and EVK2-CNR station in Nepal and northern (Qomolangma (Mt. Everest station for Atmospheric and Environmental Observation and Research, Chinese Academy of Sciences (QOMS_CAS in Tibet, China slopes of the Himalayas. While observations at QOMS_CAS and EVK2-CNR can generally be representative of a remote background atmosphere, Pokhara is an urban site with much higher aerosol load due to the influence of local anthropogenic activities. The annual mean of aerosol optical depth (AOD during the investigated period was 0.06 at QOMS_CAS, 0.04 at EVK2-CNR and 0.51 at Pokhara, respectively. Seasonal variations of aerosols are profoundly affected by large scale atmospheric circulation. Vegetation fires, peaking during April in the Himalayan region and northern India, contribute to a growing fine mode AOD at 500 nm at the three stations. Dust transported to these sites results in an increase of coarse mode AOD during the monsoon season at the three sites. Meanwhile, coarse mode AOD at EVK2-CNR is higher than QOMS_CAS from July to September, indicating the Himalayas blocks the coarse particles carried by the southwest winds. The precipitation scavenging effect is obvious at Pokhara, which can significantly reduce the aerosol load during the monsoon season. Unlike the seasonal variations, diurnal variations are mainly influenced by meso-scale systems and local topography. In general, precipitation can lead to a decrease of the aerosol load and the average particle size at each station. AOD changes in a short time with the emission rate near

  2. Meiotic Studies in Some Species of Tribe Cichorieae (Asteraceae from Western Himalayas

    Directory of Open Access Journals (Sweden)

    Raghbir Chand Gupta

    2014-01-01

    Full Text Available The present paper deals with meiotic studies in 15 species belonging to 6 genera of the tribe Cichorieae from various localities of Western Himalayas. The chromosome number has been reported for the first time in Hieracium crocatum (2n=10 and Lactuca lessertiana (2n=2x=16. Further, intraspecific variability has been reported for the first time in H. umbellatum (2n=2x=10 and 2n=6x=54, Tragopogon dubius (2n=2x=14 and 2n=4x=28, and T. gracilis (2n=2x=14. The chromosome report of 2n=2x=10 in Youngia tenuifolia is made for the first time in India. Maximum numbers of the populations show laggards, chromosome stickiness, and cytomixis from early prophase to telophase-II, leading to the formation of aneuploid cells or meiocytes with double chromosome number. Such meiotic abnormalities produce unreduced pollen grains and the reduced pollen viability.

  3. Meiotic studies in some species of tribe Cichorieae (Asteraceae) from Western Himalayas.

    Science.gov (United States)

    Gupta, Raghbir Chand; Goyal, Henna; Singh, Vijay; Goel, Rajesh Kumar

    2014-01-01

    The present paper deals with meiotic studies in 15 species belonging to 6 genera of the tribe Cichorieae from various localities of Western Himalayas. The chromosome number has been reported for the first time in Hieracium crocatum (2n = 10) and Lactuca lessertiana (2n = 2x = 16). Further, intraspecific variability has been reported for the first time in H. umbellatum (2n = 2x = 10 and 2n = 6x = 54), Tragopogon dubius (2n = 2x = 14 and 2n = 4x = 28), and T. gracilis (2n = 2x = 14). The chromosome report of 2n = 2x = 10 in Youngia tenuifolia is made for the first time in India. Maximum numbers of the populations show laggards, chromosome stickiness, and cytomixis from early prophase to telophase-II, leading to the formation of aneuploid cells or meiocytes with double chromosome number. Such meiotic abnormalities produce unreduced pollen grains and the reduced pollen viability.

  4. Seismic Character of Moho Beneath the NW Himalaya and Ladakh Inferred from Regional Earthquakes Travel Time Data

    Science.gov (United States)

    Kanna, Nagaraju; Prakasam, K. S.; Gupta, Sandeep

    2017-03-01

    We study the uppermost mantle velocities and dip of Indian Moho beneath the NW Himalaya and Ladakh using 42 regional waveform data recorded on 15 seismographs along a 600 km-long profile. We use the two-way travel time and interstation velocity methods. The apparent Pn and Sn velocities beneath the NW Himalaya are 8.08 ± 0.04 and 4.64 ± 0.07 km/s for earthquakes occurring south of the profile (downdip, western Indian shield) and 8.70 ± 0.13 and 4.76 ± 0.12 km/s for earthquakes from north (updip, western Tibet). Similarly, these velocities beneath Ladakh are 7.18 ± 0.07 and 4.32 ± 0.05 km/s for earthquakes due south (downdip, north Indian shield) and 8.50 ± 0.10 and 4.39 ± 0.12 km/s for earthquakes due north (updip, western Tibet). These velocity variations constrain the Moho dip at 2.4 ± 0.14º beneath the NW Himalaya and 6.6 ± 0.54º beneath Ladakh. Considering the varying dips along the profile, we observe that the true Pn (8.37 ± 0.07 km/s) and Sn (4.70 ± 0.1 km/s) velocities are higher for the NW Himalaya than for Ladakh (7.73 ± 0.08 and 4.33 ± 0.09 km/s). The large variation in interstation Pn velocity is observed between the station pairs near the Indus Zangpo Suture zone due to steep dipping ( 7.1º to 6.26º) of the Indian Moho. In the Himalaya region, the interstation and average values of the velocities and Moho dip are comparable, whereas a variation is observed in different segments of the Ladakh region. The results show that the Indian Moho is underthrusting at a shallow angle ( 2.5º) beneath the Himalaya, steepens abruptly ( 6.6º) further north of the Southern Tibetan Detachment and continues at a shallow angle ( 3.8º) beneath Ladakh.

  5. Earthquake Risk Analysis and Science for Peace in Western/ Kashmir Himalayas - A Road Map for Transnational Subsurface Earth Imaging

    Science.gov (United States)

    Tandon, K.

    2006-12-01

    In light of immense human tragedy caused by the Kashmir earthquake of October 8, 2005, there is a need for transnational science for the assessment of future earthquake risks and understanding continental dynamics within the Western and Kashmir Himalayas. One can approach such a test to our society through understanding what causes these earthquakes in Kashmir in the first place in a rigorous manner and also try to determine how often do they happen in Western/ Kashmir Himalayas. Geophysical measurements (passive source, active source seismology, magnetotelluric measurements, Ground Penetrating Radar (GPR)) are imaging techniques for earth's deeper as well as shallow structure. When such imaging techniques are used on scales of earth's crust and beyond (~30 km to 100 km) and also on near the surface (~10 to100 meters) of the earth, it helps us understand both the processes for the origin and frequency of the earthquakes. Here, I will only concentrate on a road map for planning regional reflection seismology (active source seismology) surveys within the context of National Science Foundation (NSF) led Science for Peace Initiative primarily involving USA, India, and Pakistan. The proposal here is to initiate shallow and deep active source surveys in mega-population cities in Punjab and adjoining areas in Western Himalayas on either side of the political boundaries of India and Pakistan as separate ventures for first few years but a start for future collaboration. Once the core scientific teams are formed involving Indian, Pakistani, American, and scientists from other nations too, then the Indus Kohistan Seismic Zone in the Kashmir Himalayas should be the target for detailed geophysical and geological investigations. The idea presented here was first formed for the NSF sponsored International Karakoram-Kashmir Workshop that was supposed to be held in Islamabad (Pakistan), May 2006 with around 100 invitees from 10 nations for forming joint scientific initiatives

  6. Holocene extreme hydrological events and their climatic implications: evidence from the middle Satluj valley, western Himalaya, India

    Science.gov (United States)

    Sharma, Shubhra; Shukla, Anil; Marh, Bhupinder; Bartarya, Sukesh; Juyal, Navin

    2016-04-01

    Extreme hydrological events and associated climatic processes are investigated and inferred through palaeoflood deposits preserved in the middle Satluj valley, India. Satluj River is the largest tributary of the Indus River having third largest catchment area in the Himalaya. Both Indian summer monsoon (ISM) and the mid-latitude westerlies contribute to the hydrological budget of the river. The steep southern orographic front prevents the northward penetration of ISM, while the mid-latitude westerlies bring moisture in form of winter snow to the orogenic interiors. It has been observed that the floods in the Himalaya are intimately associated with the variability in the above climate systems. The optical chronology indicates that floods were clustered around three time domains. The oldest flood phase-1 is dated to ˜14-12 ka which climatically occurred during the initiation of the ISM after the Last Glacial Maximum. The second phase-2 is dated between 8-5 ka and is attributed to the moderate ISM. Whereas, the youngest phase-3 is assigned the Little Ice Age (LIA) and were associated with the variability in the mid-latitude westerlies. Geochemical analyses suggest that floods were generated in higher Himalayan crystalline (HHC) zone, as the extreme precipitation destabilised the precipitous slopes creating Landslide induced Lake Outbursts Floods (LLOFs). Further, the average interval between floods has decreased since 14 ka from 500 years, to 250 years and 100 years during respective flood phases. The southern slopes of Himalaya are influenced by both the monsoon and mid-latitude westerlies and any abrupt changes in the circulation pattern were found to associate with heavy rainfall events in this region. Although an interaction between the westerlies and the monsoon is implicated for extreme floods in the western Himalaya. However, exact mechanism of these interactions is still illusive except for the observational based studies which state that extreme floods

  7. Functional selectivity in CB(2) cannabinoid receptor signaling and regulation: implications for the therapeutic potential of CB(2) ligands.

    Science.gov (United States)

    Atwood, Brady K; Wager-Miller, James; Haskins, Christopher; Straiker, Alex; Mackie, Ken

    2012-02-01

    Receptor internalization increases the flexibility and scope of G protein-coupled receptor (GPCR) signaling. CB(1) and CB(2) cannabinoid receptors undergo internalization after sustained exposure to agonists. However, it is not known whether different agonists internalize CB(2) to different extents. Because CB(2) is a promising therapeutic target, understanding its trafficking in response to different agonists is necessary for a complete understanding of its biology. Here we profile a number of cannabinoid receptor ligands and provide evidence for marked functional selectivity of cannabinoid receptor internalization. Classic, aminoalkylindole, bicyclic, cannabilactone, iminothiazole cannabinoid, and endocannabinoid ligands varied greatly in their effects on CB(1) and CB(2) trafficking. Our most striking finding was that (R)-(+)-[2,3-dihydro-5-methyl-3-(4-morpholinylmethyl) pyrrolo-[1,2,3-d,e]-1,4-benzoxazin-6-yl]-1-naphthalenyl-methanone (WIN55,212-2) (and other aminoalkylindoles) failed to promote CB(2) receptor internalization, whereas 5-(1,1-dimethylheptyl)-2-(5-hydroxy-2-(3-hydroxypropyl)cyclohexyl)phenol (CP55,940) robustly internalized CB(2) receptors. Furthermore, WIN55,212-2 competitively antagonized CP55,940-induced CB(2) internalization. Despite these differences in internalization, both compounds activated CB(2) receptors as measured by extracellular signal-regulated kinase 1/2 phosphorylation and recruitment of β-arrestin(2) to the membrane. In contrast, whereas CP55,940 inhibited voltage-gated calcium channels via CB(2) receptor activation, WIN55,212-2 was ineffective on its own and antagonized the effects of CP55,940. On the basis of the differences we found between these two ligands, we also tested the effects of other cannabinoids on these signaling pathways and found additional evidence for functional selectivity of CB(2) ligands. These novel data highlight that WIN55,212-2 and other cannabinoids show strong functional selectivity at CB(2

  8. Climatic and geologic controls on suspended sediment flux in the Sutlej River Valley, western Himalaya

    Directory of Open Access Journals (Sweden)

    H. Wulf

    2012-07-01

    Full Text Available The sediment flux through Himalayan rivers directly impacts water quality and is important for sustaining agriculture as well as maintaining drinking-water and hydropower generation. Despite the recent increase in demand for these resources, little is known about the triggers and sources of extreme sediment flux events, which lower water quality and account for extensive hydropower reservoir filling and turbine abrasion. Here, we present a comprehensive analysis of the spatiotemporal trends in suspended sediment flux based on daily data during the past decade (2001–2009 from four sites along the Sutlej River and from four of its main tributaries. In conjunction with satellite data depicting rainfall and snow cover, air temperature and earthquake records, and field observations, we infer climatic and geologic controls of peak suspended sediment concentration (SSC events. Our study identifies three key findings: First, peak SSC events (≥ 99th SSC percentile coincide frequently (57–80% with heavy rainstorms and account for about 30% of the suspended sediment flux in the semi-arid to arid interior of the orogen. Second, we observe an increase of suspended sediment flux from the Tibetan Plateau to the Himalayan Front at mean annual timescales. This sediment-flux gradient suggests that averaged, modern erosion in the western Himalaya is most pronounced at frontal regions, which are characterized by high monsoonal rainfall and thick soil cover. Third, in seven of eight catchments, we find an anticlockwise hysteresis loop of annual sediment flux variations with respect to river discharge, which appears to be related to enhanced glacial sediment evacuation during late summer. Our analysis emphasizes the importance of unconsolidated sediments in the high-elevation sector that can easily be mobilized by hydrometeorological events and higher glacial-meltwater contributions. In future climate change scenarios, including continuous glacial retreat and

  9. Climatic control on extreme sediment transfer from Dokriani Glacier during monsoon, Garhwal Himalaya (India)

    Indian Academy of Sciences (India)

    Amit Kumar; Akshaya Verma; Dwarika Prasad Dobhal; Manish Mehta; Kapil Kesarwani

    2014-02-01

    In the Himalayas, most of the glaciers are covered by thick debris, especially in the ablation zone. Supraglacial debris cover might play an important role for sediment budget of the glaciated area or for the ablation of ice masses mantled in debris. During summer season, proglacial meltwater carries considerable amount of suspended sediment. The deglaciated area provides a ready source of sediment during Indian Summer Monsoon (ISM). The heavy sediment load from the glaciers affects the hydropower generation, irrigation and drinking water supply. Therefore, to understand the sediment delivery from glaciated basins, characteristics and variation of the suspended sediment concentrations in the proglacial meltwater stream, Dokriani Glacier, have been monitored during the ablation season (May– September). Suspended sediment samples were collected near the snout of Dokriani Glacier, Garhwal Himalaya, in 2010 and 2011. Results show that mean monthly suspended sediment concentrations (SSC) were 1499, 2303, 3845 and 1649 mg/l for the months June, July, August, and September, respectively, indicating highest concentration in August followed by July. Over the period of recording, daily mean suspended concentration in the melt stream varied from 13–9798.2 mg/l, which is very high, caused due to a flash flood event during the monitoring period. The mean daily suspended sediment concentration was computed to be 2196 mg/l. The suspended sediment concentration begins to increase with discharge from May and reduces in September. Present study provides TRMM (Tropical Rainfall Measuring Mission) derived and field based hydro-meteorological insight about severe rainstorms during the years 2010 and 2011 in the study area, which transported large amounts of sediment.

  10. A Survey of Obstetric Healthcare Utilization in the Rural Western Indian Himalayas.

    Science.gov (United States)

    Prochaska, Erica C; Uniyal, V P; Lanham, Michael; Heisler, Mic