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Sample records for high-altitude ice caps

  1. Possible Mechanisms for Turbofan Engine Ice Crystal Icing at High Altitude

    Science.gov (United States)

    Tsao, Jen-Ching; Struk, Peter M.; Oliver, Michael J.

    2016-01-01

    A thermodynamic model is presented to describe possible mechanisms of ice formation on unheated surfaces inside a turbofan engine compression system from fully glaciated ice crystal clouds often formed at high altitude near deep convective weather systems. It is shown from the analysis that generally there could be two distinct types of ice formation: (1) when the "surface freezing fraction" is in the range of 0 to 1, dominated by the freezing of water melt from fully or partially melted ice crystals, the ice structure is formed from accretion with strong adhesion to the surface, and (2) when the "surface melting fraction" is the range of 0 to 1, dominated by the further melting of ice crystals, the ice structure is formed from accumulation of un-melted ice crystals with relatively weak bonding to the surface. The model captures important qualitative trends of the fundamental ice-crystal icing phenomenon reported earlier (Refs. 1 and 2) from the research collaboration work by NASA and the National Research Council (NRC) of Canada. Further, preliminary analysis of test data from the 2013 full scale turbofan engine ice crystal icing test (Ref. 3) conducted in the NASA Glenn Propulsion Systems Laboratory (PSL) has also suggested that (1) both types of ice formation occurred during the test, and (2) the model has captured some important qualitative trend of turning on (or off) the ice crystal ice formation process in the tested engine low pressure compressor (LPC) targeted area under different icing conditions that ultimately would lead to (or suppress) an engine core roll back (RB) event.

  2. Correlating Ice Cores from Quelccaya Ice Cap with Chronology from Little Ice Age Glacial Extents

    Science.gov (United States)

    Stroup, J. S.; Kelly, M. A.; Lowell, T. V.

    2010-12-01

    Proxy records indicate Southern Hemisphere climatic changes during the Little Ice Age (LIA; ~1300-1850 AD). In particular, records of change in and around the tropical latitudes require attention because these areas are sensitive to climatic change and record the dynamic interplay between hemispheres (Oerlemans, 2005). Despite this significance, relatively few records exist for the southern tropics. Here we present a reconstruction of glacial fluctuations of Quelccaya Ice Cap (QIC), Peruvian Andes, from pre-LIA up to the present day. In the Qori Kalis valley, extensive sets of moraines exist beginning with the 1963 AD ice margin (Thompson et al., 2006) and getting progressively older down valley. Several of these older moraines can be traced and are continuous with moraines in the Challpa Cocha valley. These moraines have been dated at chronology of past ice cap extents are correlated with ice core records from QIC which show an accumulation increase during ~1500-1700 AD and an accumulation decrease during ~1720-1860 AD (Thompson et al., 1985; 1986; 2006). In addition, other proxy records from Peru and the tropics are correlated with the records at QIC as a means to understand climate conditions during the LIA. This work forms the basis for future modeling of the glacial system during the LIA at QIC and for modeling of past temperature and precipitation regimes at high altitude in the tropics.

  3. Polar Ice Caps: a Canary for the Greenland Ice Sheet

    Science.gov (United States)

    Honsaker, W.; Lowell, T. V.; Sagredo, E.; Kelly, M. A.; Hall, B. L.

    2010-12-01

    Ice caps are glacier masses that are highly sensitive to climate change. Because of their hypsometry they can have a binary state. When relatively slight changes in the equilibrium line altitude (ELA) either intersect or rise above the land the ice can become established or disappear. Thus these upland ice masses have a fast response time. Here we consider a way to extract the ELA signal from independent ice caps adjacent to the Greenland Ice Sheet margin. It may be that these ice caps are sensitive trackers of climate change that also impact the ice sheet margin. One example is the Istorvet Ice Cap located in Liverpool Land, East Greenland (70.881°N, 22.156°W). The ice cap topography and the underlying bedrock surface dips to the north, with peak elevation of the current ice ranging in elevation from 1050 to 745 m.a.s.l. On the eastern side of the ice mass the outlet glaciers extending down to sea level. The western margin has several small lobes in topographic depressions, with the margin reaching down to 300 m.a.s.l. Topographic highs separate the ice cap into at least 5 main catchments, each having a pair of outlet lobes toward either side of the ice cap. Because of the regional bedrock slope each catchment has its own elevation range. Therefore, as the ELA changes it is possible for some catchments of the ice cap to experience positive mass balance while others have a negative balance. Based on weather observations we estimate the present day ELA to be ~1000 m.a.s.l, meaning mass balance is negative for the majority of the ice cap. By tracking glacier presence/absence in these different catchments, we can reconstruct small changes in the ELA. Another example is the High Ice Cap (informal name) in Milne Land (70.903°N, 25.626°W, 1080 m), East Greenland. Here at least 4 unconformities in ice layers found near the southern margin of the ice cap record changing intervals of accumulation and ablation. Therefore, this location may also be sensitive to slight

  4. Ice nuclei measurements at a high altitude remote station in the Northern Apennines

    Science.gov (United States)

    Schrod, Jann; Bingemer, Heinz; Haunold, Werner; Curtius, Joachim; Decesari, Stefano; Marinoni, Angela; Rinaldi, Matteo; Bonasoni, Paolo; Cristofanelli, Paolo

    2013-04-01

    During a field campaign of the PEGASOS (Pan-European Gas-AeroSOls-climate interactions Study, http://pegasos.iceht.forth.gr/) project in June 2012 we have made daily ice nucleus measurements on top of the Monte Cimone (44.18° N, 10.70° E, 2165 m asl) in the Northern Apennines at the "O. Vittori" Climate Observatory. Samples were taken at this GAW-WMO Global Station in a six hour rhythm (4 a.m., 10 a.m., 4 p.m. and 10 p.m.) and at increased frequency during specific events (e.g. dust transport episodes). Ice nuclei were measured by an offline technique. Aerosol particles of 40 liters of air were collected by electrostatic precipitation on a silicon substrate. Subsequently the ice nuclei were analyzed in the vacuum diffusion chamber FRIDGE [Klein et al. 2010] (FRankfurt Ice Nuclei Deposition FreezinG Experiment) by exposing the particles to supersaturation with respect to ice (106 % to 119 %) at -8 ° C, -13 ° C and -18 ° C. In our setup ice nuclei are activated in deposition and condensation freezing modes. A camera detects and counts ice crystals grown on ice nuclei. Every ice crystal counted is assumed to represent at least one ice nucleus. The mean IN concentration at Mt. Cimone was 60 IN per liter (at -18 ° C and 119% relative humility over ice), significantly higher than a longstanding mean at Mt. Kleiner Feldberg (30 IN/l), Germany for June. A mean active site density (IN per surface area of large aerosol particles) of 2.3 * 109 m-2 was calculated. The origin of the air masses sampled was established based on backward trajectories. With more than 100 IN/l on average (at -18° C and 119% relative humility over ice) the samples originating from North Africa were highest, and activated fractions were 4 to 20 times higher than for other transport sectors. An intensive event of dust transport was recorded by several instruments in the middle of June. At its peak in the morning of the 21st of June large aerosol surface and mass concentrations were observed by

  5. Seismic explosion sources on an ice cap

    DEFF Research Database (Denmark)

    Shulgin, Alexey; Thybo, Hans

    2015-01-01

    crustal model can be modelled. A crucial challenge for applying the technique is to control the sources. Here, we present data that describe the efficiency of explosive sources in the ice cover. Analysis of the data shows, that the ice cap traps a significant amount of energy, which is observed......Controlled source seismic investigation of crustal structure below ice covers is an emerging technique. We have recently conducted an explosive refraction/wide-angle reflection seismic experiment on the ice cap in east-central Greenland. The data-quality is high for all shot points and a full...

  6. Predicting abundance and variability of ice nucleating particles in precipitation at the high-altitude observatory Jungfraujoch

    Directory of Open Access Journals (Sweden)

    E. Stopelli

    2016-07-01

    Full Text Available Nucleation of ice affects the properties of clouds and the formation of precipitation. Quantitative data on how ice nucleating particles (INPs determine the distribution, occurrence and intensity of precipitation are still scarce. INPs active at −8 °C (INPs−8 were observed for 2 years in precipitation samples at the High-Altitude Research Station Jungfraujoch (Switzerland at 3580 m a.s.l. Several environmental parameters were scanned for their capability to predict the observed abundance and variability of INPs−8. Those singularly presenting the best correlations with observed number of INPs−8 (residual fraction of water vapour, wind speed, air temperature, number of particles with diameter larger than 0.5 µm, season, and source region of particles were implemented as potential predictor variables in statistical multiple linear regression models. These models were calibrated with 84 precipitation samples collected during the first year of observations; their predictive power was successively validated on the set of 15 precipitation samples collected during the second year. The model performing best in calibration and validation explains more than 75 % of the whole variability of INPs−8 in precipitation and indicates that a high abundance of INPs−8 is to be expected whenever high wind speed coincides with air masses having experienced little or no precipitation prior to sampling. Such conditions occur during frontal passages, often accompanied by precipitation. Therefore, the circumstances when INPs−8 could be sufficiently abundant to initiate the ice phase in clouds may frequently coincide with meteorological conditions favourable to the onset of precipitation events.

  7. Identifications of the polar cap boundary and the auroral belt in the high-altitude magnetosphere: a model for field-aligned currents

    International Nuclear Information System (INIS)

    Sugiura, M.

    1975-01-01

    By means of the Ogo 5 Goddard Space Flight Center fluxgate magnetometer data the polar cap boundary is identified in the high-altitude magnetosphere by a sudden transition from a dipolar field to a more taillike configuration. It is inferred that there exists a field-aligned-current layer at the polar cap boundary. In the night side magnetosphere the polar cap boundary is identified as the high-latitude boundary of the plasma sheet. The field-aligned current flows downward to the ionosphere on the morning side of the magnetosphere and upward from the ionosphere on the afternoon side. The basic pattern of the magnetic field variations observed during the satellite's traversal of the auroral belt is presented. Currents flow in opposite directions in the two field-aligned-current layers. The current directions in these layers as observed by Ogo 5 in the high-altitude magnetosphere are the same as those observed at low altitudes by the polar-orbiting Triad satellite (Armstrong and Zmuda, 1973). The magnetic field in the region where the lower-latitude field-aligned-current layer is situated is essentially meridional. A model is presented in which two field-aligned-current systems, one at the polar cap boundary and the other on the low-latitude part of the auroral belt, are main []y connected by ionospheric currents flowing across the auroral belt. The existence of field-aligned currents deduced from the Ogo 5 observations is a permanent feature of the magnetosphere. Intensifications of the field-aligned currents and occurrences of multiple pairs of field-aligned-current layers characterize the disturbed conditions of these regions

  8. Little Ice Age Fluctuations of Quelccaya Ice Cap, Peru

    Science.gov (United States)

    Stroup, J. S.; Kelly, M. A.; Lowell, T.

    2009-12-01

    A record of the past extents of Quelccaya Ice Cap (QIC) provides valuable information about tropical climate change from late glacial to recent time. Here, we examine the timing and regional significance of fluctuations of QIC during the Little Ice Age (LIA; ~1300-1850 AD). One prominent set of moraines, known as the Huancane I moraines, is located ~1 km from the present-day western ice cap margin and provides a near-continuous outline of the most recent advance of QIC. This moraine set was radiocarbon dated (~298 ± 134 and 831 ± 87 yr BP) by Mercer and Palacios (1977) and presented as some of the first evidence for cooling in the tropics during the Little Ice Age. Recent field investigations in the QIC region focused on refining the chronology of the Huancane I moraines. In 2008, new stratigraphic sections exposed by local lake-flooding events revealed multiple layers of peat within the Huancane I moraines. In both 2008 and 2009, samples were obtained for 10Be dating of boulders on Huancane I moraines. A combination of radiocarbon and 10Be ages indicate that the Huancane I moraines were deposited by ice cap expansion after ~3800 yr BP and likely by multiple advances at approximately 1000, 600, 400, and 200 yr BP. Radiocarbon and 10Be chronologies of the Huancane I moraines are compared with the Quelccaya ice core records (Thompson et al., 1985; 1986; 2006). Accumulation data from the ice core records are interpreted to indicate a significant wet period at ~1500-1700 AD followed by a significant drought at ~1720-1860 AD. We examine ice marginal fluctuations during these times to determine influence of such events on the ice cap extent.

  9. Isotopic signatures for natural versus anthropogenic Pb in high-altitude Mt. Everest ice cores during the past 800 years

    International Nuclear Information System (INIS)

    Lee, Khanghyun; Hur, Soon Do; Hou, Shugui; Burn-Nunes, Laurie J.; Hong, Sungmin; Barbante, Carlo; Boutron, Claude F.; Rosman, Kevin J.R.

    2011-01-01

    A long-term record, extending back 800 years (1205 to 2002 AD), of the Pb isotopic composition ( 206 Pb/ 207 Pb and 208 Pb/ 207 Pb) as well as Pb concentrations from high altitude Mt. Everest ice cores has the potential to identify sources and source regions affecting natural and anthropogenic Pb deposition in central Asia. The results show that the regional natural background Pb isotope signature (∼ 1.20 for 206 Pb/ 207 Pb and ∼ 2.50 for 208 Pb/ 207 Pb) in the central Himalayas was dominated by mineral dust over the last ∼ 750 years from 1205 to 1960s, mostly originating from local sources with occasional contributions of long-range transported dust probably from Sahara desert and northwestern India. Since the 1970s, the Pb isotope ratios are characterized by a continuous decline toward less radiogenic ratios with the least mean ratios of 1.178 for 206 Pb/ 207 Pb and 2.471 for 208 Pb/ 207 Pb in the period 1990–1996. The depression of the 206 Pb/ 207 Pb and 208 Pb/ 207 Pb values during the corresponding periods is most likely due to an increasing influence of less radiogenic Pb of anthropogenic origin mainly from leaded gasoline used in South Asia (India as well as possibly Bangladesh and Nepal). From 1997 to 2002, isotopic composition tends to show a shift to slightly more radiogenic signature. This is likely attributed to reducing Pb emissions from leaded gasoline in source regions, coinciding with the nationwide reduction of Pb in gasoline and subsequent phase-out of leaded gasoline in South Asia since 1997. An interesting feature is the relatively high levels of Pb concentrations and enrichment factors (EF) between 1997 and 2002. Although the reason for this feature remains uncertain, it would be probably linked with an increasing influence of anthropogenic Pb emitted from other sources such as fossil fuel combustion and non-ferrous metal production.

  10. Acoustic Monitoring of the Arctic Ice Cap

    Science.gov (United States)

    Porter, D. L.; Goemmer, S. A.; Chayes, D. N.

    2012-12-01

    Introduction The monitoring of the Arctic Ice Cap is important economically, tactically, and strategically. In the scenario of ice cap retreat, new paths of commerce open, e.g. waterways from Northern Europe to the Far East. Where ship-going commerce is conducted, the U.S. Navy and U.S. Coast Guard have always stood guard and been prepared to assist from acts of nature and of man. It is imperative that in addition to measuring the ice from satellites, e.g. Icesat, that we have an ability to measure the ice extent, its thickness, and roughness. These parameters play an important part in the modeling of the ice and the processes that control its growth or shrinking and its thickness. The proposed system consists of three subsystems. The first subsystem is an acoustic source, the second is an array of geophones and the third is a system to supply energy and transmit the results back to the analysis laboratory. The subsystems are described below. We conclude with a plan on how to tackle this project and the payoff to the ice cap modeler and hence the users, i.e. commerce and defense. System Two historically tested methods to generate a large amplitude multi-frequency sound source include explosives and air guns. A new method developed and tested by the University of Texas, ARL is a combustive Sound Source [Wilson, et al., 1995]. The combustive sound source is a submerged combustion chamber that is filled with the byproducts of the electrolysis of sea water, i.e. Hydrogen and Oxygen, an explosive mixture which is ignited via a spark. Thus, no additional compressors, gases, or explosives need to be transported to the Arctic to generate an acoustic pulse capable of the sediment and the ice. The second subsystem would be geophones capable of listening in the O(10 Hz) range and transmitting that data back to the laboratory. Thus two single arrays of geophones arranged orthogonal to each other with a range of 1000's of kilometers and a combustive sound source where the two

  11. Isotopic signatures for natural versus anthropogenic Pb in high-altitude Mt. Everest ice cores during the past 800 years

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Khanghyun; Hur, Soon Do [Korea Polar Research Institute, Songdo Techno Park, 7-50, Songdo-dong, Yeonsu-gu, Incheon 406-840 (Korea, Republic of); Hou, Shugui [State Key Laboratory of Cryospheric Science, Cold and Arid Regions Environmental and Engineering Research Institute, Chinese Academy of Science, Lanzhou 730000 (China); School of Geographic and Oceanographic Sciences, Nanjing University, Nanjing 210093 (China); Burn-Nunes, Laurie J. [Department of Imaging and Applied Physics, Curtin University of Technology, GPO Box U1987, Perth, WA 6845 (Australia); Hong, Sungmin, E-mail: smhong@inha.ac.kr [Department of Ocean Sciences, Inha University, 253 Yonghyun-dong, Nam-gu, Incheon, 402-751 (Korea, Republic of); Barbante, Carlo [Department of Environmental Sciences, University Ca' Foscari of Venice, Dorsoduro 2137, 30 123 Venice (Italy); Institute for the Dynamics of Environmental Processes-CNR, University Ca' Foscari of Venice, Dorsoduro 2137, 30 123 Venice (Italy); Boutron, Claude F. [Laboratoire de Glaciologie et Geophysique de l' Environnement (UMR Universite Joseph Fourier/CNRS 5183 ), 54 rue Moliere, BP 96, 38402 Saint Martin d' Heres Cedex (France); Unite de Formation et de Recherche ' Physique, Ingenierie, Terre, Environnement, Mecanique' , Universite Joseph Fourier de Grenoble ( Institut Universitaire de France ), 715 rue de la Houille Blanche, BP 53, 38041 Grenoble Cedex 9 (France); Rosman, Kevin J.R. [Department of Imaging and Applied Physics, Curtin University of Technology, GPO Box U1987, Perth, WA 6845 (Australia)

    2011-12-15

    A long-term record, extending back 800 years (1205 to 2002 AD), of the Pb isotopic composition ({sup 206}Pb/{sup 207}Pb and {sup 208}Pb/{sup 207}Pb) as well as Pb concentrations from high altitude Mt. Everest ice cores has the potential to identify sources and source regions affecting natural and anthropogenic Pb deposition in central Asia. The results show that the regional natural background Pb isotope signature ({approx} 1.20 for {sup 206}Pb/{sup 207}Pb and {approx} 2.50 for {sup 208}Pb/{sup 207}Pb) in the central Himalayas was dominated by mineral dust over the last {approx} 750 years from 1205 to 1960s, mostly originating from local sources with occasional contributions of long-range transported dust probably from Sahara desert and northwestern India. Since the 1970s, the Pb isotope ratios are characterized by a continuous decline toward less radiogenic ratios with the least mean ratios of 1.178 for {sup 206}Pb/{sup 207}Pb and 2.471 for {sup 208}Pb/{sup 207}Pb in the period 1990-1996. The depression of the {sup 206}Pb/{sup 207}Pb and {sup 208}Pb/{sup 207}Pb values during the corresponding periods is most likely due to an increasing influence of less radiogenic Pb of anthropogenic origin mainly from leaded gasoline used in South Asia (India as well as possibly Bangladesh and Nepal). From 1997 to 2002, isotopic composition tends to show a shift to slightly more radiogenic signature. This is likely attributed to reducing Pb emissions from leaded gasoline in source regions, coinciding with the nationwide reduction of Pb in gasoline and subsequent phase-out of leaded gasoline in South Asia since 1997. An interesting feature is the relatively high levels of Pb concentrations and enrichment factors (EF) between 1997 and 2002. Although the reason for this feature remains uncertain, it would be probably linked with an increasing influence of anthropogenic Pb emitted from other sources such as fossil fuel combustion and non-ferrous metal production.

  12. Devon island ice cap: core stratigraphy and paleoclimate.

    Science.gov (United States)

    Koerner, R M

    1977-04-01

    Valuable paleoclimatic information can be gained by studying the distribution of melt layers in deep ice cores. A profile representing the percentage of ice in melt layers in a core drilled from the Devon Island ice cap plotted against both time and depth shows that the ice cap has experienced a period of very warm summers since 1925, following a period of colder summers between about 1600 and 1925. The earlier period was coldest between 1680 and 1730. There is a high correlation between the melt-layer ice percentage and the mass balance of the ice cap. The relation between them suggests that the ice cap mass balance was zero (accumulation equaled ablation) during the colder period but is negative in the present warmer one. There is no firm evidence of a present cooling trend in the summer conditions on the ice cap. A comparison with the melt-layer ice percentage in cores from the other major Canadian Arctic ice caps shows that the variation of summer conditions found for the Devon Island ice cap is representative for all the large ice caps for about 90 percent of the time. There is also a good correlation between melt-layer percentage and summer sea-ice conditions in the archipelago. This suggests that the search for the northwest passage was influenced by changing climate, with the 19th-century peak of the often tragic exploration coinciding with a period of very cold summers.

  13. Variability of IN measured with the Fast Ice Nucleus Chamber (FINCH) at the high altitude research station Jungfraujoch during wintertime 2013

    Science.gov (United States)

    Frank, Fabian; Nillius, Björn; Bundke, Ulrich; Curtius, Joachim

    2014-05-01

    Ice nuclei (IN) are an important component of the atmospheric aerosol. Despite their low concentrations in the atmosphere, they have an influence on the formation of ice crystals in mixed-phase clouds and therefore on precipitation. The Fast Ice Nucleus CHamber (FINCH)1, a counter for ice nucleating particles developed at the Goethe University Frankfurt am Main allows long-term measurements of the IN number concentration. In FINCH the ice activation of the aerosol particles is achieved by mixing air flows with different temperature and humidity. The IN number concentration measurements at different meteorological conditions during the INUIT-JFJ campaign at the high altitude research station Jungfraujoch in Switzerland are presented and its variability are discussed. The good operational performance of the instrument allowed up to 10 hours of continuous measurements. Acknowledgment: This work was supported by the German Research Foundation, DFG Grant: BU 1432/3-2 BU 1432/4-1 in the framework of INUIT (FOR 1525) and SPP 1294 HALO. 1- Bundke, U., Nillius, B., Jaenicke, R., Wetter, T., Klein, H., and Bingemer, H. (2008). The fast ice nucleus chamber finch. Atmospheric Research, 90:180-186.

  14. Glaciers and ice caps outside Greenland

    Science.gov (United States)

    Sharp, Marin; Wolken, G.; Burgess, D.; Cogley, J.G.; Copland, L.; Thomson, L.; Arendt, A.; Wouters, B.; Kohler, J.; Andreassen, L.M.; O'Neel, Shad; Pelto, M.

    2015-01-01

    Mountain glaciers and ice caps cover an area of over 400 000 km2 in the Arctic, and are a major influence on global sea level (Gardner et al. 2011, 2013; Jacob et al. 2012). They gain mass by snow accumulation and lose mass by meltwater runoff. Where they terminate in water (ocean or lake), they also lose mass by iceberg calving. The climatic mass balance (Bclim, the difference between annual snow accumulation and annual meltwater runoff) is a widely used index of how glaciers respond to climate variability and change. The total mass balance (ΔM) is defined as the difference between annual snow accumulation and annual mass losses (by iceberg calving plus runoff).

  15. The Horizontal Ice Nucleation Chamber (HINC): INP measurements at conditions relevant for mixed-phase clouds at the High Altitude Research Station Jungfraujoch

    Science.gov (United States)

    Lacher, Larissa; Lohmann, Ulrike; Boose, Yvonne; Zipori, Assaf; Herrmann, Erik; Bukowiecki, Nicolas; Steinbacher, Martin; Kanji, Zamin A.

    2017-12-01

    In this work we describe the Horizontal Ice Nucleation Chamber (HINC) as a new instrument to measure ambient ice-nucleating particle (INP) concentrations for conditions relevant to mixed-phase clouds. Laboratory verification and validation experiments confirm the accuracy of the thermodynamic conditions of temperature (T) and relative humidity (RH) in HINC with uncertainties in T of ±0.4 K and in RH with respect to water (RHw) of ±1.5 %, which translates into an uncertainty in RH with respect to ice (RHi) of ±3.0 % at T > 235 K. For further validation of HINC as a field instrument, two measurement campaigns were conducted in winters 2015 and 2016 at the High Altitude Research Station Jungfraujoch (JFJ; Switzerland, 3580 m a. s. l. ) to sample ambient INPs. During winters 2015 and 2016 the site encountered free-tropospheric conditions 92 and 79 % of the time, respectively. We measured INP concentrations at 242 K at water-subsaturated conditions (RHw = 94 %), relevant for the formation of ice clouds, and in the water-supersaturated regime (RHw = 104 %) to represent ice formation occurring under mixed-phase cloud conditions. In winters 2015 and 2016 the median INP concentrations at RHw = 94 % was below the minimum detectable concentration. At RHw = 104 %, INP concentrations were an order of magnitude higher, with median concentrations in winter 2015 of 2.8 per standard liter (std L-1; normalized to standard T of 273 K and pressure, p, of 1013 hPa) and 4.7 std L-1 in winter 2016. The measurements are in agreement with previous winter measurements obtained with the Portable Ice Nucleation Chamber (PINC) of 2.2 std L-1 at the same location. During winter 2015, two events caused the INP concentrations at RHw = 104 % to significantly increase above the campaign average. First, an increase to 72.1 std L-1 was measured during an event influenced by marine air, arriving at the JFJ from the North Sea and the Norwegian Sea. The contribution from anthropogenic or other

  16. Elevation Changes of Ice Caps in the Canadian Arctic Archipelago

    Science.gov (United States)

    Abdalati, W.; Krabill, W.; Frederick, E.; Manizade, S.; Martin, C.; Sonntag, J.; Swift, R.; Thomas, R.; Yungel, J.; Koerner, R.

    2004-01-01

    Precise repeat airborne laser surveys were conducted over the major ice caps in the Canadian Arctic Archipelago in the spring of 1995 and 2000 in order to measure elevation changes in the region. Our measurements reveal thinning at lower elevations (below 1600 m) on most of the ice caps and glaciers, but either very little change or thickening at higher elevations in the ice cap accumulation zones. Recent increases in precipitation in the area can account for the slight thickening where it was observed, but not for the thinning at lower elevations. For the northern ice caps on the Queen Elizabeth Islands, thinning was generally less than 0.5 m/yr , which is consistent with what would be expected from the warm temperature anomalies in the region for the 5-year period between surveys and appears to be a continuation of a trend that began in the mid 1980s. Further south, however, on the Barnes and Penny ice caps on Baffin Island, this thinning was much more pronounced at over 1 m/yr in the lower elevations. Here temperature anomalies were very small, and the thinning at low elevations far exceeds any associated enhanced ablation. The observations on Barnes, and perhaps Penny are consistent with the idea that the observed thinning is part of a much longer term deglaciation, as has been previously suggested for Barnes Ice Cap. Based on the regional relationships between elevation and elevation-change in our data, the 1995-2000 mass balance for the region is estimated to be 25 cu km/yr of ice, which corresponds to a sea level increase of 0.064 mm/ yr . This places it among the more significant sources of eustatic sea level rise, though not as substantial as Greenland ice sheet, Alaskan glaciers, or the Patagonian ice fields.

  17. Athletes at High Altitude.

    Science.gov (United States)

    Khodaee, Morteza; Grothe, Heather L; Seyfert, Jonathan H; VanBaak, Karin

    2016-01-01

    Athletes at different skill levels perform strenuous physical activity at high altitude for a variety of reasons. Multiple team and endurance events are held at high altitude and may place athletes at increased risk for developing acute high altitude illness (AHAI). Training at high altitude has been a routine part of preparation for some of the high level athletes for a long time. There is a general belief that altitude training improves athletic performance for competitive and recreational athletes. A review of relevant publications between 1980 and 2015 was completed using PubMed and Google Scholar. Clinical review. Level 3. AHAI is a relatively uncommon and potentially serious condition among travelers to altitudes above 2500 m. The broad term AHAI includes several syndromes such as acute mountain sickness (AMS), high altitude pulmonary edema (HAPE), and high altitude cerebral edema (HACE). Athletes may be at higher risk for developing AHAI due to faster ascent and more vigorous exertion compared with nonathletes. Evidence regarding the effects of altitude training on athletic performance is weak. The natural live high, train low altitude training strategy may provide the best protocol for enhancing endurance performance in elite and subelite athletes. High altitude sports are generally safe for recreational athletes, but they should be aware of their individual risks. Individualized and appropriate acclimatization is an essential component of injury and illness prevention.

  18. High altitude illness

    Science.gov (United States)

    Hartman-Ksycińska, Anna; Kluz-Zawadzka, Jolanta; Lewandowski, Bogumił

    High-altitude illness is a result of prolonged high-altitude exposure of unacclimatized individuals. The illness is seen in the form of acute mountain sickness (AMS) which if not treated leads to potentially life-threatening high altitude pulmonary oedema and high-altitude cerebral oedema. Medical problems are caused by hypobaric hypoxia stimulating hypoxia-inducible factor (HIF) release. As a result, the central nervous system, circulation and respiratory system function impairment occurs. The most important factor in AMS treatment is acclimatization, withdrawing further ascent and rest or beginning to descent; oxygen supplementation, and pharmacological intervention, and, if available, a portable hyperbaric chamber. Because of the popularity of high-mountain sports and tourism better education of the population at risk is essential.

  19. HIGH-ALTITUDE ILLNESS

    Directory of Open Access Journals (Sweden)

    Dwitya Elvira

    2015-05-01

    Full Text Available AbstrakHigh-altitude illness (HAI merupakan sekumpulan gejala paru dan otak yang terjadi pada orang yang baru pertama kali mendaki ke ketinggian. HAI terdiri dari acute mountain sickness (AMS, high-altitude cerebral edema (HACE dan high-altitude pulmonary edema (HAPE. Tujuan tinjauan pustaka ini adalah agar dokter dan wisatawan memahami risiko, tanda, gejala, dan pengobatan high-altitude illness. Perhatian banyak diberikan terhadap penyakit ini seiring dengan meningkatnya popularitas olahraga ekstrim (mendaki gunung tinggi, ski dan snowboarding dan adanya kemudahan serta ketersediaan perjalanan sehingga jutaan orang dapat terpapar bahaya HAI. Di Pherice, Nepal (ketinggian 4343 m, 43% pendaki mengalami gejala AMS. Pada studi yang dilakukan pada tempat wisata di resort ski Colorado, Honigman menggambarkan kejadian AMS 22% pada ketinggian 1850 m sampai 2750 m, sementara Dean menunjukkan 42% memiliki gejala pada ketinggian 3000 m. Aklimatisasi merupakan salah satu tindakan pencegahan yang dapat dilakukan sebelum pendakian, selain beberapa pengobatan seperti asetazolamid, dexamethasone, phosopodiestrase inhibitor, dan ginko biloba.Kata kunci: high-altitude illness, acute mountain sickness, edema cerebral, pulmonary edema AbstractHigh-altitude illness (HAI is symptoms of lung and brain that occurs in people who first climb to altitude. HAI includes acute mountain sickness (AMS, high-altitude cerebral edema (HACE and high altitude pulmonary edema (HAPE. The objective of this review was to understand the risks, signs, symptoms, and treatment of high-altitude illness. The attention was given to this disease due to the rising popularity of extreme sports (high mountain climbing, skiing and snowboarding and the ease and availability of the current travelling, almost each year, millions of people could be exposed to the danger of HAI. In Pherice, Nepal (altitude 4343 m, 43% of climbers have symptoms of AMS. Furthermore, in a study conducted at sites in

  20. Ice Caps and Ice Belts: The Effects of Obliquity on Ice−Albedo Feedback

    Energy Technology Data Exchange (ETDEWEB)

    Rose, Brian E. J. [Department of Atmospheric and Environmental Sciences, University at Albany (State University of New York), 1400 Washington Avenue, Albany, NY 12222 (United States); Cronin, Timothy W. [Program in Atmospheres, Oceans, and Climate, Massachusetts Institute of Technology 77 Massachusetts Avenue, Cambridge, MA 02139 (United States); Bitz, Cecilia M., E-mail: brose@albany.edu [Department of Atmospheric Sciences, MS 351640, University of Washington, Seattle, WA 98195-1640 (United States)

    2017-09-01

    Planetary obliquity determines the meridional distribution of the annual mean insolation. For obliquity exceeding 55°, the weakest insolation occurs at the equator. Stable partial snow and ice cover on such a planet would be in the form of a belt about the equator rather than polar caps. An analytical model of planetary climate is used to investigate the stability of ice caps and ice belts over the widest possible range of parameters. The model is a non-dimensional diffusive Energy Balance Model, representing insolation, heat transport, and ice−albedo feedback on a spherical planet. A complete analytical solution for any obliquity is given and validated against numerical solutions of a seasonal model in the “deep-water” regime of weak seasonal ice line migration. Multiple equilibria and unstable transitions between climate states (ice-free, Snowball, or ice cap/belt) are found over wide swaths of parameter space, including a “Large Ice-Belt Instability” and “Small Ice-Belt Instability” at high obliquity. The Snowball catastrophe is avoided at weak radiative forcing in two different scenarios: weak albedo feedback and inefficient heat transport (favoring stable partial ice cover), or efficient transport at high obliquity (favoring ice-free conditions). From speculative assumptions about distributions of planetary parameters, three-fourths to four-fifths of all planets with stable partial ice cover should be in the form of Earth-like polar caps.

  1. The Horizontal Ice Nucleation Chamber (HINC: INP measurements at conditions relevant for mixed-phase clouds at the High Altitude Research Station Jungfraujoch

    Directory of Open Access Journals (Sweden)

    L. Lacher

    2017-12-01

    Full Text Available In this work we describe the Horizontal Ice Nucleation Chamber (HINC as a new instrument to measure ambient ice-nucleating particle (INP concentrations for conditions relevant to mixed-phase clouds. Laboratory verification and validation experiments confirm the accuracy of the thermodynamic conditions of temperature (T and relative humidity (RH in HINC with uncertainties in T of ±0.4 K and in RH with respect to water (RHw of ±1.5 %, which translates into an uncertainty in RH with respect to ice (RHi of ±3.0 % at T > 235 K. For further validation of HINC as a field instrument, two measurement campaigns were conducted in winters 2015 and 2016 at the High Altitude Research Station Jungfraujoch (JFJ; Switzerland, 3580 m a. s. l.  to sample ambient INPs. During winters 2015 and 2016 the site encountered free-tropospheric conditions 92 and 79 % of the time, respectively. We measured INP concentrations at 242 K at water-subsaturated conditions (RHw = 94 %, relevant for the formation of ice clouds, and in the water-supersaturated regime (RHw = 104 % to represent ice formation occurring under mixed-phase cloud conditions. In winters 2015 and 2016 the median INP concentrations at RHw = 94 % was below the minimum detectable concentration. At RHw = 104 %, INP concentrations were an order of magnitude higher, with median concentrations in winter 2015 of 2.8 per standard liter (std L−1; normalized to standard T of 273 K and pressure, p, of 1013 hPa and 4.7 std L−1 in winter 2016. The measurements are in agreement with previous winter measurements obtained with the Portable Ice Nucleation Chamber (PINC of 2.2 std L−1 at the same location. During winter 2015, two events caused the INP concentrations at RHw = 104 % to significantly increase above the campaign average. First, an increase to 72.1 std L−1 was measured during an event influenced by marine air, arriving at the JFJ

  2. High Altitude and Heart

    Directory of Open Access Journals (Sweden)

    Murat Yalcin

    2011-04-01

    Full Text Available Nowadays, situations associated with high altitude such as mountaineering, aviation increasingly draw the attention of people. Gas pressure decreases and hypoxia is encountered when climbing higher. Physiological and pathological responses of human body to different heights are different. Therefore, physiological and pathological changes that may occur together with height and to know the clinical outcomes of these are important . Acute mountain sickness caused by high altitude and high altitude cerebral edema are preventable diseases with appropriate precautions. Atmospheric oxygen decreasing with height, initiates many adaptive mechanisms. These adaptation mechanisms and acclimatization vary widely among individuals because of reasons such as environmental factors, exercise and cold. High altitude causes different changes in the cardiovascular system with various mechanisms. Although normal individuals easily adapt to these changes, this situation can lead to undesirable results in people with heart disease. For this reason, it should be known the effective evaluation of the people with known heart disease before traveling to high altitude and the complications due to the changes with height and the recommendations can be made to these patients. [TAF Prev Med Bull 2011; 10(2.000: 211-222

  3. High altitude organic gold

    DEFF Research Database (Denmark)

    Pouliot, Mariève; Pyakurel, Dipesh; Smith-Hall, Carsten

    2018-01-01

    Ethnopharmacological relevance Ophiocordyceps sinensis (Berk.) G.H.Sung, J.M.Sung, Hywel-Jones & Spatafora, a high altitude Himalayan fungus-caterpillar product found in alpine meadows in China, Bhutan, Nepal, and India, has been used in the Traditional Chinese Medicine system for over 2000 years...

  4. Atmospheric heavy metals in tropical South America during the past 22,000 years recorded in a high altitude ice core from Sajama, Bolivia.

    Science.gov (United States)

    Hong, Sungmin; Barbante, Carlo; Boutron, Claude; Gabrielli, Paolo; Gaspari, Vania; Cescon, Paolo; Thompson, Lonnie; Ferrari, Christophe; Francou, Bernard; Maurice-Bourgoin, Laurence

    2004-04-01

    V, Co, Cu, Zn, As, Rb, Sr, Ag, Cd, Ba, Pb, Bi and U have been analysed by inductively coupled plasma sector field mass spectrometry in various sections of a dated snow/ice core drilled at an altitude of 6542 m on the Sajama ice cap in Bolivia. The analysed sections were dated from the Last Glacial Stage ( approximately 22,000 years ago), the Mid-Holocene and the last centuries. The observed variations of crustal enrichment factors (EFc) for the various metals show contrasting situations. For V, Co, Rb, Sr and U, EFc values close to unity are observed for all sections, then showing that these elements are mainly derived from rock and soil dust. For the other metals, clear time trends are observed, with a pronounced increase of EFc values during the 19th and 20th centuries. This increase shows evidence of metal pollution associated with human activity in South America. For Pb an important contribution was from gasoline additives. For metals such as Cu, Zn, Ag and Cd an important contribution was from metal production activities, with a continuous increase of production during the 20th century in countries such as Peru, Chile and Bolivia.

  5. Landscape Evolution and the Reincarnation of the Southern Residual Ice Cap

    Science.gov (United States)

    Byrne, S.; Zuber, M. T.

    2006-10-01

    Given the present rate of erosion on the southern residual ice cap, it is unlikely that any part of the cap is older than a few centuries. Unless we're lucky, why is there a residual cap present today for us to observe? We propose a solution involving constant destruction and renewal of the cap.

  6. Late-glacial and Holocene history of changes in Quelccaya Ice Cap, Peru

    Science.gov (United States)

    Kelly, M. A.; Lowell, T. V.; Schaefer, J. M.; Finkel, R. C.

    2008-12-01

    Quelccaya Ice Cap in the southeastern Peruvian Andes (~13-14° S latitude) is an icon for climate change. Its rapidly receding outlet, Qori Kalis Glacier, has been monitored since the 1970's. Cores from Quelccaya Ice Cap provide high-resolution information about temperature and precipitation during the past 1,500 years. We extend the understanding of past changes in Quelccaya Ice Cap based on mapping and dating of glacial moraines and associated deposits. Our results include fifty 10Be ages of moraines and bedrock as well as twenty-nine 14C ages of organic material associated with moraines. These results form the basis of a chronology of changes in Quelccaya Ice Cap from ~16,000 yr BP to late Holocene time. Results from 10Be and 14C dating indicate that Quelccaya Ice Cap experienced a significant advance at 12,700-11,400 yr BP. Subsequent to this advance, the ice margin deposited at least three recessional moraine sets. Quelccaya Ice Cap receded to near its present-day margin by ~10,000 yr BP. Neoglacial advances began by ~3,000 yr BP and culminated with a maximum advance during the Little Ice Age. This chronology fits well with prior work which indicates a restricted Quelccaya Ice Cap during middle Holocene time. Moreover, the overlap between moraine and ice core data for the last 1,500 years provides a unique opportunity to assess the influences of temperature and precipitation on past ice cap extents.

  7. High altitude dermatology

    Directory of Open Access Journals (Sweden)

    G K Singh

    2017-01-01

    Full Text Available Approximately, 140 million people worldwide live permanently at high altitudes (HAs and approximately another 40 million people travel to HA area (HAA every year for reasons of occupation, sports or recreation. In India, whole of Ladakh region, part of Northwest Kashmir, Northern part of Sikkim and Tenga valley of Arunachal are considered inhabited areas of HAA. The low quantity of oxygen, high exposure of ultraviolet (UV light, very low humidity, extreme subzero temperature in winter, high wind velocity, make this region difficult for lowlanders as well as for tourists. Acute mountain sickness, HA pulmonary edema, HA cerebral edema, and thromboembolic conditions are known to occur in HA. However, enough knowledge has not been shared on dermatoses peculiar to this region. Xerosis, UV-related skin disorders (tanning, photomelanosis, acute and chronic sunburn, polymorphic light eruption, chronic actinic dermatitis, actinic cheilitis, etc., cold injuries (frostbite, chilblains, acrocyanosis, erythrocyanosis, etc. nail changes (koilonychias, airborne contact dermatitis, insect bite reaction, and skin carcinoma (basal cell carcinomas, squamous cell carcinomas, and also rarely malignant melanoma are the dermatoses seen in HAAs. Early diagnosis and knowledge of HA dermatoses may prevent serious consequences of disease and improve the quality of life for the visitors as well as for native of the place.

  8. Barnes Ice Cap South Dome Trilateration Net Survey Data 1970-1984, Version 1

    Data.gov (United States)

    National Aeronautics and Space Administration — The Barnes Ice Cap data set contains survey measurements of a network of 43 stakes along a 10 km flow line on the northeast flank of the south dome of the Barnes Ice...

  9. Brain Food at High Altitude.

    Science.gov (United States)

    Jain, Vishal

    2016-01-01

    Scenic view at high altitude is a pleasure to the eyes, but it has some shortcoming effects as well. High altitude can be divided into different categories, i.e., high altitude (3000-5000 ft), very high altitude (5000-8000 ft), and extreme altitude (above 8000 ft). Much of the population resides at high altitude, and others go there for tourism. Military personnel are also posted there to defend boundaries. As we ascent to high altitude, partial pressure of oxygen reduces, whereas concentration remains the same; this reduces the availability of oxygen to different body parts. This pathophysiological condition is known as hypobaric hypoxia (HH) which leads to oxidative stress and further causes cognitive dysfunction in some cases. Hypoxia causes neurodegeneration in different brain regions; however, the hippocampus is found to be more prone in comparison to other brain regions. As the hippocampus is affected most, therefore, spatial memory is impaired most during such condition. This chapter will give a brief review of the damaging effect of high altitude on cognition and also throw light on possible herbal interventions at high altitude, which can improve cognitive performance as well as provide protection against the deteriorating effect of hypobaric hypoxia at high altitude.

  10. The Gregoriev Ice Cap length changes derived by 2-D ice flow line model for harmonic climate histories

    OpenAIRE

    Konovalov, Y. V.; Nagornov, O. V.

    2009-01-01

    Different ice thickness distributions along the flow line and the flow line length changes of the Gregoriev Ice Cap, Terskey Ala-Tau, Central Asia, were obtained for some surface mass balance histories which can be considered as possible surface mass balances in the future. The ice cap modeling was performed by solving of steady state hydrodynamic equations in the case of low Reynolds number in the form of the mechanical equilibrium equation in terms of stress deviator components coupled with...

  11. Interannual observations and quantification of summertime H2O ice deposition on the Martian CO2 ice south polar cap

    Science.gov (United States)

    Brown, Adrian J.; Piqueux, Sylvain; Titus, Timothy N.

    2014-01-01

    The spectral signature of water ice was observed on Martian south polar cap in 2004 by the Observatoire pour l'Mineralogie, l'Eau les Glaces et l'Activite (OMEGA) ( Bibring et al., 2004). Three years later, the OMEGA instrument was used to discover water ice deposited during southern summer on the polar cap ( Langevin et al., 2007). However, temporal and spatial variations of these water ice signatures have remained unexplored, and the origins of these water deposits remains an important scientific question. To investigate this question, we have used observations from the Compact Reconnaissance Imaging Spectrometer for Mars (CRISM) instrument on the Mars Reconnaissance Orbiter (MRO) spacecraft of the southern cap during austral summer over four Martian years to search for variations in the amount of water ice. We report below that for each year we have observed the cap, the magnitude of the H2O ice signature on the southern cap has risen steadily throughout summer, particularly on the west end of the cap. The spatial extent of deposition is in disagreement with the current best simulations of deposition of water ice on the south polar cap (Montmessin et al., 2007). This increase in water ice signatures is most likely caused by deposition of atmospheric H2O ice and a set of unusual conditions makes the quantification of this transport flux using CRISM close to ideal. We calculate a ‘minimum apparent‘ amount of deposition corresponding to a thin H2O ice layer of 0.2 mm (with 70% porosity). This amount of H2O ice deposition is 0.6–6% of the total Martian atmospheric water budget. We compare our ‘minimum apparent’ quantification with previous estimates. This deposition process may also have implications for the formation and stability of the southern CO2 ice cap, and therefore play a significant role in the climate budget of modern day Mars.

  12. High Arctic Holocene temperature record from the Agassiz ice cap and Greenland ice sheet evolution.

    Science.gov (United States)

    Lecavalier, Benoit S; Fisher, David A; Milne, Glenn A; Vinther, Bo M; Tarasov, Lev; Huybrechts, Philippe; Lacelle, Denis; Main, Brittany; Zheng, James; Bourgeois, Jocelyne; Dyke, Arthur S

    2017-06-06

    We present a revised and extended high Arctic air temperature reconstruction from a single proxy that spans the past ∼12,000 y (up to 2009 CE). Our reconstruction from the Agassiz ice cap (Ellesmere Island, Canada) indicates an earlier and warmer Holocene thermal maximum with early Holocene temperatures that are 4-5 °C warmer compared with a previous reconstruction, and regularly exceed contemporary values for a period of ∼3,000 y. Our results show that air temperatures in this region are now at their warmest in the past 6,800-7,800 y, and that the recent rate of temperature change is unprecedented over the entire Holocene. The warmer early Holocene inferred from the Agassiz ice core leads to an estimated ∼1 km of ice thinning in northwest Greenland during the early Holocene using the Camp Century ice core. Ice modeling results show that this large thinning is consistent with our air temperature reconstruction. The modeling results also demonstrate the broader significance of the enhanced warming, with a retreat of the northern ice margin behind its present position in the mid Holocene and a ∼25% increase in total Greenland ice sheet mass loss (∼1.4 m sea-level equivalent) during the last deglaciation, both of which have implications for interpreting geodetic measurements of land uplift and gravity changes in northern Greenland.

  13. Using Airborne SAR Interferometry to Measure the Elevation of a Greenland Ice Cap

    DEFF Research Database (Denmark)

    Dall, Jørgen; Keller, K.; Madsen, S.N.

    2000-01-01

    A digital elevation model (DEM) of an ice cap in Greenland has been generated from airborne SAR interferometry data, calibrated with a new algorithm, and compared with airborne laser altimetry profiles and carrier-phase differential GPS measurements of radar reflectors deployed on the ice cap...... with GPS data and calibrated laser data....

  14. Mass balance of Greenland and the Canadian Ice Caps from combined altimetry and GRACE inversion

    DEFF Research Database (Denmark)

    Forsberg, René; Simonsen, Sebastian Bjerregaard; Sørensen, Louise Sandberg

    The combination of GRACE and altimetry data may yield a high resolution mass balance time series of the Greenlandice sheet, highlighting the varying individual mass loss behaviour of major glaciers. By including the Canadian arctic ice caps in the estimation, a more reliable estimate of the mass...... loss of both Greenlandand the Canadian ice caps may be obtained, minimizing the leakage errors otherwise unavoidable by GRACE. Actually, the absolute value of the Greenlandice sheet mass loss is highly dependent on methods and how the effects of Arctic Canadian ice caps are separated in the GRACE...... loss of the ice caps and ice sheet basins for the period 2003-15. This period shows a marked increase of ice sheet melt, especially in NW and NE Greenland, but also show large variability, with the melt anomaly year of 2012 showing a record mass loss, followed by 2013 with essentially no Greenland mass...

  15. The projected demise of Barnes Ice Cap: Evidence of an unusually warm 21st century Arctic

    Science.gov (United States)

    Gilbert, A.; Flowers, G. E.; Miller, G. H.; Refsnider, K. A.; Young, N. E.; Radić, V.

    2017-03-01

    As a remnant of the Laurentide Ice Sheet, Barnes Ice Cap owes its existence and present form in part to the climate of the last glacial period. The ice cap has been sustained in the present interglacial climate by its own topography through the mass balance-elevation feedback. A coupled mass balance and ice-flow model, forced by Coupled Model Intercomparison Project Phase 5 climate model output, projects that the current ice cap will likely disappear in the next 300 years. For greenhouse gas Representative Concentration Pathways of +2.6 to +8.5 Wm-2, the projected ice-cap survival times range from 150 to 530 years. Measured concentrations of cosmogenic radionuclides 10Be, 26Al, and 14C at sites exposed near the ice-cap margin suggest the pending disappearance of Barnes Ice Cap is very unusual in the last million years. The data and models together point to an exceptionally warm 21st century Arctic climate.

  16. delta 18O variations in snow on the Devon Island ice cap, Northwest Territories, Canada

    International Nuclear Information System (INIS)

    Koerner, R.; Russel, R.D.

    1979-01-01

    A study of delta 18 O variations of snow samples taken on traverses across the Devon Island ice cap in June 1971, 1972, and 1973 has shown a difference between the accumulation conditions on the souteast and nortwest sides of the ice cap. On the souteast side there is an increasing depletion of 18 O in the snow with increasing elevation. This pattern is attibuted to the effect of orographic uplift of air masses moving over the ice cap from the southeast, which promotes condensation and precipitation due to adiabatic cooling. On the northwest side of the ice cap there is no evidence of any further depletion of 18 O in snow, neither with increasing distance from the possible moisture source in Baffin Bay to the southeast nor with increasing elevation if the air mass comes from the northwest. In this case condensation is due to isobaric cooling so that precipitation is generally from level cloud bases. The changes inferred for the isotopic composition of the water vapour as it rises up the southeast slope are found to be consistent with its depletion through precipitation under near-equilibrium conditions. It is calculated that approximately 30% of the moisture at sea level on the southeast side of the ice cap and 8% at the top of the ice cap are of local origin. Lower temporal and aerial variability of the delta values on the southeast side of the ice cap is attributed to dominance of the Baffin Bay low on that side Effecting consistency of storm conditions there. The delta values of ice in the ablation zone on the Sverdrup Glacier show the combined effect of ice movement from the accumulation to the ablation zone and climatic change during the period of movement from cold to warm and back to cold conditions again. (auth)

  17. High-altitude pulmonary hypertension

    Directory of Open Access Journals (Sweden)

    X-Q. Xu

    2009-03-01

    Full Text Available High-altitude pulmonary hypertension (HAPH is a specific disease affecting populations that live at high elevations. The prevalence of HAPH among those residing at high altitudes needs to be further defined. Whereas reduction in nitric oxide production may be one mechanism for the development of HAPH, the roles of endothelin-1 and prostaglandin I2 pathways in the pathogenesis of HAPH deserve further study. Although some studies have suggested that genetic factors contribute to the pathogenesis of HAPH, data published to date are insufficient for the identification of a significant number of gene polymorphims in HAPH. The clinical presentation of HAPH is nonspecific. Exertional dyspnoea is the most common symptom and signs related to right heart failure are common in late stages of HAPH. Echocardiography is the most useful screening tool and right heart catheterisation is the gold standard for the diagnosis of HAPH. The ideal management for HAPH is migration to lower altitudes. Phosphodiesterase 5 is an attractive drug target for the treatment of HAPH. In addition, acetazolamide is a promising therapeutic agent for high-altitude pulmonary hypertension. To date, no evidence has confirmed whether endothelin-receptor antagonists have efficacy in the treatment of high-altitude pulmonary hypertension.

  18. Glaciological and chemical studies on ice cores from Hans Tausen ice cap, Greenland

    DEFF Research Database (Denmark)

    Clausen, H.B.; Stampe, Mia; Hammer, C.U.

    2001-01-01

    The paper presents studies of various chemical and isotopical parameters from ice cores drilled in the northernmost located ice cap, Hans Tausen Iskappe, Pearyland, Greenland (HT). The 346 m main core (MC95) was drilled to bedrock in 1995 as well as a 35 m shallow core (SC95). A 60 m shallow core...... (SC75) and a 51 m shallow core (SC76) was drilled at two different positions in 1975 and 1976, respectively. A 6 m shallow core (SC94) was drilled in 1994. Continuous stable isotope records exist for all of these cores, total b-activity only from SC75 and SC76. Continuous ECM inferred acidity records...... exist along the 1995 cores (MC95 and SC95) and finally detailed records of dust and water soluble ion concentrations exist on selected parts of MC95. To determine a time scale for the ice core is an important prerequisite for the interpretation of other records. The age scale is based on acid layers...

  19. Barnes Ice Cap South Dome Trilateration Net Survey Data 1970-1984

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Barnes Ice Cap data set contains survey measurements of a network of 43 stakes along a 10 km flow line on the northeast flank of the south dome of the Barnes Ice...

  20. Acute high-altitude sickness

    Directory of Open Access Journals (Sweden)

    Andrew M. Luks

    2017-02-01

    Full Text Available At any point 1–5 days following ascent to altitudes ≥2500 m, individuals are at risk of developing one of three forms of acute altitude illness: acute mountain sickness, a syndrome of nonspecific symptoms including headache, lassitude, dizziness and nausea; high-altitude cerebral oedema, a potentially fatal illness characterised by ataxia, decreased consciousness and characteristic changes on magnetic resonance imaging; and high-altitude pulmonary oedema, a noncardiogenic form of pulmonary oedema resulting from excessive hypoxic pulmonary vasoconstriction which can be fatal if not recognised and treated promptly. This review provides detailed information about each of these important clinical entities. After reviewing the clinical features, epidemiology and current understanding of the pathophysiology of each disorder, we describe the current pharmacological and nonpharmacological approaches to the prevention and treatment of these diseases.

  1. Landscape Evolution and the Reincarnation of the Residual CO2 Ice Cap of Mars

    Science.gov (United States)

    Byrne, S.; Zuber, M.

    2006-12-01

    Observations of the southern residual CO2 cap of Mars reveal a wide range of landforms including flat-floored quasi-circular pits with steep walls (dubbed Swiss-cheese features). Interannual comparisons show that these depressions are expanding laterally at rates of ~2m/yr to ~4m/yr, prompting suggestions of climate change. The residual CO2 ice cap is up to 10m thick and underlain by an involatile basement, it also contains layers roughly 2m thick representing different accumulation episodes in the recent past. Changes in the appearance of the residual ice between the Mariner 9 and Viking missions indicate that the top-most layer was deposited in that time-frame, soon after the global dust storm of 1971. The spatial density of the Swiss-cheese features, and the rate at which they expand, mean that it is unlikely that any part of the residual ice cap is older than a few centuries. Given this, we may ask: how can there be a residual cap present today for us to observe? To answer this and other questions we have developed a model to examine the evolution of a CO2 ice landscape. This model reproduces the morphologies and expansion rates seen in the actual residual CO2 ice cap. Our model results indicate that the fate of CO2 ice surfaces is controlled by their surface roughness. Surface roughness always increases with time, which results in an unstable situation. When the surface roughness exceeds a critical point small pits can begin to develop. The walls of these pits rapidly steepen and begin retreating which enlarges and deepens the pit. This situation always occurs even if the surface of the CO2 slab has a high enough albedo to have a net mass gain each year. Once these pits begin expanding they quickly erode the entire ice slab. When the underlying non-CO2 material is exposed, it will not frost over again if Mars were to repeat like clockwork every year. We conclude that interannual climatic variability is actually a requirement for the continued existence of a

  2. Erosion patterns produced by the paleo Haizishan ice cap, SE Tibetan Plateau

    Science.gov (United States)

    Fu, P.; Stroeven, A. P.; Harbor, J.; Hättestrand, C.; Heyman, J.; Caffee, M. W.

    2017-12-01

    Erosion is a primary driver of landscape evolution, topographic relief production, geochemical cycles, and climate change. Combining in situ 10Be and 26Al exposure age dating, geomorphological mapping, and field investigations, we examine glacial erosion patterns of the almost 4,000 km2 paleo Haizishan ice cap on the southeastern Tibetan Plateau. Our results show that ice caps on the low relief Haizishan Plateau produced a zonal pattern of landscape modification. In locations where apparent exposure ages on bedrock are consistent with the last deglaciation, complete resetting of the cosmogenic exposure age clock indicates glacial erosion of at least a few meters. However, older apparent exposure ages on bedrock in areas known to have been covered by the paleo ice cap during the Last Glacial Maximum indicate inheritance and thus limited glacial erosion. Inferred surface exposure ages from cosmogenic depth profiles through two saprolites vary from resetting and thus saprolite profile truncation to nuclide inheritance indicating limited erosion. Finally, significant nuclide inheritance in river sand samples from basins on the scoured plateau surface also indicate limited glacial erosion during the last glaciation. Hence, for the first time, our study shows clear evidence of preservation under non-erosive ice on the Tibetan Plateau. As patterns of glacial erosion intensity are largely driven by the basal thermal regime, our results confirm earlier inferences from geomorphology for a concentric basal thermal pattern for the paleo Haizishan ice cap during the LGM.

  3. Test of Newton's inverse-square law in the Greenland ice cap

    International Nuclear Information System (INIS)

    Ander, M.E.; Zumberge, M.A.; Lautzenhiser, T.

    1989-01-01

    An Airy-type geophysical experiment was conducted in a 2-km-deep hole in the Greenland ice cap at depths between 213 and 1673 m to test for possible violations of Newton's inverse-square law. An anomalous gravity gradient was observed. We cannot unambiguously attribute it to a breakdown of Newtonian gravity because we have shown that it might be due to unexpected geological features in the rock below the ice

  4. JAWS: Just Add Water System - A device for detection of nucleic acids in Martian ice caps

    DEFF Research Database (Denmark)

    Hansen, Anders J.; Willerslev, Eske; Mørk, Søren

    2002-01-01

    with a regulation of pH and salt concentrations e.g. the MOD systems and could be installed on a planetary probe melting its way down the Martian ice caps e.g. the NASA Cryobot. JAWS can be used for detection of remains of ancient life preserved in the Martian ice as well as for detection of contamination brought...... to the planet from Earth....

  5. Abnormal Winter Melting of the Arctic Sea Ice Cap Observed by the Spaceborne Passive Microwave Sensors

    Directory of Open Access Journals (Sweden)

    Seongsuk Lee

    2016-12-01

    Full Text Available The spatial size and variation of Arctic sea ice play an important role in Earth’s climate system. These are affected by conditions in the polar atmosphere and Arctic sea temperatures. The Arctic sea ice concentration is calculated from brightness temperature data derived from the Defense Meteorological Satellite program (DMSP F13 Special Sensor Microwave/Imagers (SSMI and the DMSP F17 Special Sensor Microwave Imager/Sounder (SSMIS sensors. Many previous studies point to significant reductions in sea ice and their causes. We investigated the variability of Arctic sea ice using the daily and monthly sea ice concentration data from passive microwave observations to identify the sea ice melting regions near the Arctic polar ice cap. We discovered the abnormal melting of the Arctic sea ice near the North Pole even during the summer and the winter. This phenomenon is hard to explain only surface air temperature or solar heating as suggested by recent studies. We propose a hypothesis explaining this phenomenon. The heat from the deep sea in Arctic Ocean ridges and/or the hydrothermal vents might be contributing to the melting of Arctic sea ice. This hypothesis could be verified by the observation of warm water column structure below the melting or thinning arctic sea ice through the project such as Coriolis dataset for reanalysis (CORA.

  6. Mass balance of the Amitsulôq ice cap, West Greenland

    DEFF Research Database (Denmark)

    Ahlstrøm, Andreas P.; Bøggild, Carl Egede; Olesen, Ole B.

    2007-01-01

    We present detailed mass balance measurements from the Amitsulôq ice cap in West Greenland spanning from 1982 to 1990. The data includes summer and winter balances from 26 stake locations distributed over five transects covering the whole ice cap. The mass balance measurements are combined...... with a recent satellite-derived digital elevation model to calculate the specific balance, which is in turn compared to discharge data from the adjacent Tasersiaq basin. The correlation between specific summer balance and discharge is R2 = 0.93 indicating that the basin discharge is dominated by glacial...... meltwater, linking the hydropower potential of the basin closely to the fate of the adjoining Greenland ice-sheet margin....

  7. Ice core records of climate variability on the Third Pole with emphasis on the Guliya ice cap, western Kunlun Mountains

    Science.gov (United States)

    Thompson, Lonnie G.; Yao, Tandong; Davis, Mary E.; Mosley-Thompson, Ellen; Wu, Guangjian; Porter, Stacy E.; Xu, Baiqing; Lin, Ping-Nan; Wang, Ninglian; Beaudon, Emilie; Duan, Keqin; Sierra-Hernández, M. Roxana; Kenny, Donald V.

    2018-05-01

    Records of recent climate from ice cores drilled in 2015 on the Guliya ice cap in the western Kunlun Mountains of the Tibetan Plateau, which with the Himalaya comprises the Third Pole (TP), demonstrate that this region has become warmer and moister since at least the middle of the 19th century. Decadal-scale linkages are suggested between ice core temperature and snowfall proxies, North Atlantic oceanic and atmospheric processes, Arctic temperatures, and Indian summer monsoon intensity. Correlations between annual-scale oxygen isotopic ratios (δ18O) and tropical western Pacific and Indian Ocean sea surface temperatures are also demonstrated. Comparisons of climate records during the last millennium from ice cores acquired throughout the TP illustrate centennial-scale differences between monsoon and westerlies dominated regions. Among these records, Guliya shows the highest rate of warming since the end of the Little Ice Age, but δ18O data over the last millennium from TP ice cores support findings that elevation-dependent warming is most pronounced in the Himalaya. This, along with the decreasing precipitation rates in the Himalaya region, is having detrimental effects on the cryosphere. Although satellite monitoring of glaciers on the TP indicates changes in surface area, only a few have been directly monitored for mass balance and ablation from the surface. This type of ground-based study is essential to obtain a better understanding of the rate of ice shrinkage on the TP.

  8. Crustal movements due to Iceland's shrinking ice caps mimic magma inflow signal at Katla volcano.

    Science.gov (United States)

    Spaans, Karsten; Hreinsdóttir, Sigrún; Hooper, Andrew; Ófeigsson, Benedikt Gunnar

    2015-05-20

    Many volcanic systems around the world are located beneath, or in close proximity to, ice caps. Mass change of these ice caps causes surface movements, which are typically neglected when interpreting surface deformation measurements around these volcanoes. These movements can however be significant, and may closely resemble movements due to magma accumulation. Here we show such an example, from Katla volcano, Iceland. Horizontal movements observed by GPS on the flank of Katla have led to the inference of significant inflow of magma into a chamber beneath the caldera, starting in 2000, and continuing over several years. We use satellite radar interferometry and GPS data to show that between 2001 and 2010, the horizontal movements seen on the flank can be explained by the response to the long term shrinking of ice caps, and that erratic movements seen at stations within the caldera are also not likely to signify magma inflow. It is important that interpretations of geodetic measurements at volcanoes in glaciated areas consider the effect of ice mass change, and previous studies should be carefully reevaluated.

  9. King George Island ice cap geometry updated with airborne GPR measurements

    Directory of Open Access Journals (Sweden)

    M. Rückamp

    2012-07-01

    Full Text Available Ice geometry is a mandatory requirement for numerical modelling purposes. In this paper we present a consistent data set for the ice thickness, the bedrock topography and the ice surface topography of the King George Island ice cap (Arctowski icefield and the adjacent central part. The new data set is composed of ground based and airborne ground penetrating radar (GPR and differential GPS (DGPS measurements, obtained during several field campaigns. Blindow et al. (2010 already provided a comprehensive overview of the ground based measurements carried out in the safely accessible area of the ice cap. The updated data set incorporates airborne measurements in the heavily crevassed coastal areas. Therefore, in this paper special attention is paid to the airborne measurements by addressing the instrument used, survey procedure, and data processing in more detail. In particular, the inclusion of airborne GPR measurements with the 30 MHz BGR-P30-System developed at the Institute of Geophysics (University of Münster completes the picture of the ice geometry substantially. The compiled digital elevation model of the bedrock shows a rough, highly variable topography with pronounced valleys, ridges, and troughs. Mean ice thickness is 240 ± 6 m, with a maximum value of 422 ± 10 m in the surveyed area. Noticeable are bounded areas in the bedrock topography below sea level where marine based ice exists. The provided data set is required as a basis for future monitoring attempts or as input for numerical modelling experiments. The data set is available from the PANGAEA database at http://dx.doi.org/10.1594/PANGAEA.770567.

  10. 110 years of local glacier and ice cap changes in Central- and North East Greenland

    Science.gov (United States)

    Bjork, A. A.; Aagaard, S.; Kjaer, K. H.; Khan, S. A.; Box, J.

    2014-12-01

    The local glaciers and ice caps of Greenland are becoming more apparent players in global sea-level rise, and their contribution to future changes is significant. Very little information on their historical fluctuations exists as much of the focus has been on the Greenland Ice Sheet. Now, we can for the first time present historic data that spans 110 years for more than 200 of the local glaciers and ice caps covering this large and important region of the Arctic. The central- and north eastern part of Greenland is of particular interest as these areas are predicted to exhibit a more active behavior with higher mass loss in the future - simultaneously with an increase in precipitation. Our results show that the glaciers and ice caps in the region are responding very rapidly to changes in temperature and precipitation. The present retreat is the fastest observed within the last eight decades, only surpassed by the rapid post LIA retreat. The 1930s was the golden era for scientific exploration in Central- and North East Greenland as several large expeditions visited the area and photographed from land, sea and air. We use historic recordings from Danish and Norwegian aerial missions and terrestrial recordings from the renowned American Explorer Louise Boyd. These unique pictures from the early 1930s form the backbone of the study and are supplemented the more recent aerial photographs the 1940s and onwards and satellite imagery from the mid-1960s and up until present. From high resolution aerial photographs we are able to map the maximum extent of the glaciers during the LIA (Little Ice Age), from which retreat in this area is estimated to commence in 1900. Using a new SMB (Surface Mass Balance) model and its components covering the entire observational period along with high resolution DEMs and historic sea-ice records we are now able to extract valuable information on the past and present triggers of glacial change.

  11. High-altitude adaptations in vertebrate hemoglobins

    DEFF Research Database (Denmark)

    Weber, Roy E.

    2007-01-01

    Vertebrates at high altitude are subjected to hypoxic conditions that challenge aerobic metabolism. O2 transport from the respiratory surfaces to tissues requires matching between the O2 loading and unloading tensions and theO2-affinity of blood, which is an integrated function of hemoglobin......, birds and ectothermic vertebrates at high altitude....

  12. Black carbon aerosols and the third polar ice cap

    Energy Technology Data Exchange (ETDEWEB)

    Menon, Surabi; Koch, Dorothy; Beig, Gufran; Sahu, Saroj; Fasullo, John; Orlikowski, Daniel

    2010-04-15

    Recent thinning of glaciers over the Himalayas (sometimes referred to as the third polar region) have raised concern on future water supplies since these glaciers supply water to large river systems that support millions of people inhabiting the surrounding areas. Black carbon (BC) aerosols, released from incomplete combustion, have been increasingly implicated as causing large changes in the hydrology and radiative forcing over Asia and its deposition on snow is thought to increase snow melt. In India BC emissions from biofuel combustion is highly prevalent and compared to other regions, BC aerosol amounts are high. Here, we quantify the impact of BC aerosols on snow cover and precipitation from 1990 to 2010 over the Indian subcontinental region using two different BC emission inventories. New estimates indicate that Indian BC emissions from coal and biofuel are large and transport is expected to expand rapidly in coming years. We show that over the Himalayas, from 1990 to 2000, simulated snow/ice cover decreases by {approx}0.9% due to aerosols. The contribution of the enhanced Indian BC to this decline is {approx}36%, similar to that simulated for 2000 to 2010. Spatial patterns of modeled changes in snow cover and precipitation are similar to observations (from 1990 to 2000), and are mainly obtained with the newer BC estimates.

  13. The distribution of snow accumulation across the Austfonna ice cap, Svalbard: direct measurements and modelling

    OpenAIRE

    Taurisano, Andrea; Schuler, Thomas V.; Hagen, Jon Ove; Eiken, Trond; Loe, Even; Melvold, Kjetil; Kohler, Jack

    2007-01-01

    We present an analysis of the spatial variability in the snow accumulation on the Austfonna ice cap in Svalbard, Norway, based on the results of field investigations conducted in the spring of 1999, 2004 and 2005. During the campaigns ground penetrating radar measurements at 500 and 800 MHz were collected along profiles, along with additional manual snow sounding and pit stratigraphy work. The analysis of the data reveals a consistent pattern in the spatial distribution of the snow accumulati...

  14. Sharply increased mass loss from glaciers and ice caps in the Canadian Arctic Archipelago.

    Science.gov (United States)

    Gardner, Alex S; Moholdt, Geir; Wouters, Bert; Wolken, Gabriel J; Burgess, David O; Sharp, Martin J; Cogley, J Graham; Braun, Carsten; Labine, Claude

    2011-05-19

    Mountain glaciers and ice caps are contributing significantly to present rates of sea level rise and will continue to do so over the next century and beyond. The Canadian Arctic Archipelago, located off the northwestern shore of Greenland, contains one-third of the global volume of land ice outside the ice sheets, but its contribution to sea-level change remains largely unknown. Here we show that the Canadian Arctic Archipelago has recently lost 61 ± 7 gigatonnes per year (Gt yr(-1)) of ice, contributing 0.17 ± 0.02 mm yr(-1) to sea-level rise. Our estimates are of regional mass changes for the ice caps and glaciers of the Canadian Arctic Archipelago referring to the years 2004 to 2009 and are based on three independent approaches: surface mass-budget modelling plus an estimate of ice discharge (SMB+D), repeat satellite laser altimetry (ICESat) and repeat satellite gravimetry (GRACE). All three approaches show consistent and large mass-loss estimates. Between the periods 2004-2006 and 2007-2009, the rate of mass loss sharply increased from 31 ± 8 Gt yr(-1) to 92 ± 12 Gt yr(-1) in direct response to warmer summer temperatures, to which rates of ice loss are highly sensitive (64 ± 14 Gt yr(-1) per 1 K increase). The duration of the study is too short to establish a long-term trend, but for 2007-2009, the increase in the rate of mass loss makes the Canadian Arctic Archipelago the single largest contributor to eustatic sea-level rise outside Greenland and Antarctica.

  15. High Artic Glaciers and Ice Caps Ice Mass Change from GRACE, Regional Climate Model Output and Altimetry.

    Science.gov (United States)

    Ciraci, E.; Velicogna, I.; Fettweis, X.; van den Broeke, M. R.

    2016-12-01

    The Arctic hosts more than the 75% of the ice covered regions outside from Greenland and Antarctica. Available observations show that increased atmospheric temperatures during the last century have contributed to a substantial glaciers retreat in all these regions. We use satellite gravimetry by the NASA's Gravity Recovery and Climate Experiment (GRACE), and apply a least square fit mascon approach to calculate time series of ice mass change for the period 2002-2016. Our estimates show that arctic glaciers have constantly contributed to the sea level rise during the entire observation period with a mass change of -170+/-20 Gt/yr equivalent to the 80% of the total ice mass change from the world Glacier and Ice Caps (GIC) excluding the Ice sheet peripheral GIC, which we calculated to be -215+/-32 GT/yr, with an acceleration of 9+/-4 Gt/yr2. The Canadian Archipelago is the main contributor to the total mass depletion with an ice mass trend of -73+/-9 Gt/yr and a significant acceleration of -7+/-3 Gt/yr2. The increasing mass loss is mainly determined by melting glaciers located in the northern part of the archipelago.In order to investigate the physical processes driving the observed ice mass loss we employ satellite altimetry and surface mass balance (SMB) estimates from Regional climate model outputs available for the same time period covered by the gravimetry data. We use elevation data from the NASA ICESat (2003-2009) and ESA CryoSat-2 (2010-2016) missions to estimate ice elevation changes. We compare GRACE ice mass estimates with time series of surface mass balance from the Regional Climate Model (RACMO-2) and the Modèle Atmosphérique Régional (MAR) and determine the portion of the total mass change explained by the SMB signal. We find that in Iceland and in the and the Canadian Archipelago the SMB signal explains most of the observed mass changes, suggesting that ice discharge may play a secondary role here. In other region, e.g. in Svalbar, the SMB signal

  16. A new field experiment in the Greenland ice cap to test Newton's inverse square law

    International Nuclear Information System (INIS)

    Ander, M.E.; Nieto, M.M.; Zumberge, M.A.; Parker, R.L.; Lautzenhiser, T.; Aiken, C.L.V.; Ferguson, J.F.; McMechan, G.A.

    1989-01-01

    Recent experimental evidence suggests that Newton's law of gravity may not be precise. There are modern theories of quantum gravity that, in their attempts to unify gravity with other forces of nature, predict non-Newtonian gravitational forces that could have ranges on the order of 10 2 --10 5 m. If they exist, these forces would be apparent as violations of Newton's inverse square law. A geophysical experiment was carried out to search for possible finite-range, non-Newtonian gravity over depths of 213--1673 m in the glacial ice of the Greenland ice cap. The principal reason for this choice of experimental site is that a hole drilled through the ice cap already existed and the uniformity of the ice eliminates one of the major sources of uncertainty arising in the first of earlier studies, namely, the heterogeneity of the rocks through which a mine shaft or drill hole passes. This paper presents observations made in the summer of 1987 at Dye 3, Greenland, in the 2033-m-deep borehole, which reached the basement rock

  17. Experimental investigation of insolation-driven dust ejection from Mars' CO2 ice caps

    Science.gov (United States)

    Kaufmann, E.; Hagermann, A.

    2017-01-01

    Mars' polar caps are - depending on hemisphere and season - partially or totally covered with CO2 ice. Icy surfaces such as the polar caps of Mars behave differently from surfaces covered with rock and soil when they are irradiated by solar light. The latter absorb and reflect incoming solar radiation within a thin layer beneath the surface. In contrast, ices are partially transparent in the visible spectral range and opaque in the infrared. Due to this fact, the solar radiation can penetrate to a certain depth and raise the temperature of the ice or dust below the surface. This may play an important role in the energy balance of icy surfaces in the solar system, as already noted in previous investigations. We investigated the temperature profiles inside CO2 ice samples including a dust layer under Martian conditions. We have been able to trigger dust eruptions, but also demonstrated that these require a very narrow range of temperature and ambient pressure. We discuss possible implications for the understanding of phenomena such as arachneiform patterns or fan shaped deposits as observed in Mars' southern polar region.

  18. The evolution of the englacial temperature distribution in the superimposed ice zone of a polar ice cap during a summer season

    NARCIS (Netherlands)

    Greuell, W.; Oerlemans, J.

    1989-01-01

    The aim of the present investigation was to provide more insight into the processes affecting the evolution of the englacial temperature distribution at a non-temperate location on a glacier. Measurements were made in the top 10 m of the ice at the summit of Laika Ice Cap (Canadian Arctic)

  19. High Altitude Clear Air Turbulence Project

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Air Force Flight Dynamics Laboratory conducted the High Altitude Clear Air Turbulence Project in the mid 1960s with the intention of better understanding air...

  20. Holocene fluctuations of Quelccaya Ice Cap, Peru based on lacustrine and surficial geologic archives

    Science.gov (United States)

    Stroup, J. S.; Kelly, M. A.; Lowell, T. V.; Beal, S. A.; Smith, C. A.

    2013-12-01

    Peru's Quelccaya Ice Cap (QIC; 13.9°S, 70.8°W, ~5200-5670 m asl) is an important site for understanding tropical paleoclimate, mainly because of annually layered ice cores that provide an ~1800 year long record of tropical paleoclimatic conditions (e.g., Thompson et al., 2013). Here, we present a detailed record of QIC fluctuations using surficial deposits and lake sediments that extend back to late glacial time. We compare the late Holocene records of QIC 10Be-dated moraines and ice core data with lake sediments from a nearby glacially fed lake to establish the framework we use to interpret a Holocene long sediment record from a glacially fed lake. We also examine sediments from a nearby non-glacial lake to constrain non-glacial clastic input. We collected two ~5 m-long sediment cores, one from Laguna Challpacocha, which is currently fed by QIC meltwater, and one from the Laguna Yanacocha, which has not received QIC meltwater since ~12.3 ka. Changes in magnetic susceptibility, loss on ignition, bulk density and X-ray fluorescence chemistry combined with 14C and 210Pb chronologies provide information about sediment transported to the lakes. Retreat from the late Holocene extent defined by the 10Be-dated moraine record (~0.52 ka) is contemporaneous with a sharp transition from organic to clastic sedimentation in the Challpacocha core at ~ 0.52 ka. This implies that glacially-sourced clastic sedimentation, as tracked by loss on ignition, Ti counts and bulk density, increased during ice cap recession. Based on these same proxy data, we suggest the following Holocene history of QIC: QIC receded from the Challpacocha basin by ~10.6 ka. Increased clastic sedimentation at 8.2 - 4.1, 3.6 - 2.7 ka and from 0.55 ka - present are interpreted as times of ice cap recession. The increased clastic sedimentation at ~8.2 - 4.1 ka is consistent with surficial deposits near the present-day ice margin that indicate that at ~7.0 - 4.6 ka QIC was smaller than at present (Buffen et al

  1. Azimuthal Structure of the Sand Erg that Encircles the North Polar Water-Ice Cap

    Science.gov (United States)

    Teodoro, L. A.; Elphic, R. C.; Eke, V. R.; Feldman, W. C.; Maurice, S.; Pathare, A.

    2011-12-01

    The sand erg that completely encircles the perennial water-ice cap that covers the Martian north geographic pole displays considerable azimuthal structure as seen in visible and near-IR images. Much of this structure is associated with the terminations of the many steep troughs that cut spiral the approximately 3 km thick polar ice cap. Other contributions come from the katabatic winds that spill over steep-sided edges of the cap, such as what bounds the largest set of dunes that comprise Olympia Undae. During the spring and summer months when these winds initiate from the higher altitudes that contain sublimating CO2 ice, which is very cold and dry, heat adiabatically when they compress as they lose altitude. These winds should then remove H2O moisture from the uppermost layer of the sand dunes that are directly in their path. Two likely locations where this desiccation may occur preferentially is at the termination of Chasma Boreale and the ice cap at Olympia Undae. We will search for this effect by sharpening the spatial structure of the epithermal neutron counting rates measured at northern high latitudes using the Mars Odyssey Neutron Spectrometer (MONS). The epithermal range of neutron energies is nearly uniquely sensitive to the hydrogen content of surface soils, which should likely be in the form of H2O/OH molecules/radicals. We therefore convert epithermal counting rates in terms of Water-Equivalent-Hydrogen, WEH. However, MONS counting-rate data have a FWHM of ~550 km., which is sufficiently broad to prevent a close association of WEH variability with images of geological features. In this study, we reduce spurious features in the instrument smeared neutron counting rates through deconvolution. We choose the PIXON numerical deconvolution technique for this purpose. This technique uses a statistical approach (Pina 2001, Eke 2001), which is capable of removing spurious features in the data in the presence of noise. We have previously carried out a detailed

  2. The 20th century retreat of ice caps in Iceland derived from airborne SAR

    DEFF Research Database (Denmark)

    Magnússon, Eyjólfur; Björnsson, Helgi; Dall, Jørgen

    2005-01-01

    with the Danish airborne EMISAR radar system. Polarimetric and interferometric SAR data reveal the margins of the present ice caps as well as a series of terminal moraines in the fore field. These moraines date back to the maximum Neoglacial extent at the end of the 19th century and the outermost allow...... of the surges in W-Vatnajokull in the 20th century are observed in the SAR data including the most recent surges in the 1990s. Interestingly no push moraines were observed in front of the surge advance, but the moraines appear when the glaciers start retreating. We estimate that the collective decrease...

  3. Calibrating a surface mass-balance model for Austfonna ice cap, Svalbard

    Science.gov (United States)

    Schuler, Thomas Vikhamar; Loe, Even; Taurisano, Andrea; Eiken, Trond; Hagen, Jon Ove; Kohler, Jack

    2007-10-01

    Austfonna (8120 km2) is by far the largest ice mass in the Svalbard archipelago. There is considerable uncertainty about its current state of balance and its possible response to climate change. Over the 2004/05 period, we collected continuous meteorological data series from the ice cap, performed mass-balance measurements using a network of stakes distributed across the ice cap and mapped the distribution of snow accumulation using ground-penetrating radar along several profile lines. These data are used to drive and test a model of the surface mass balance. The spatial accumulation pattern was derived from the snow depth profiles using regression techniques, and ablation was calculated using a temperature-index approach. Model parameters were calibrated using the available field data. Parameter calibration was complicated by the fact that different parameter combinations yield equally acceptable matches to the stake data while the resulting calculated net mass balance differs considerably. Testing model results against multiple criteria is an efficient method to cope with non-uniqueness. In doing so, a range of different data and observations was compared to several different aspects of the model results. We find a systematic underestimation of net balance for parameter combinations that predict observed ice ablation, which suggests that refreezing processes play an important role. To represent these effects in the model, a simple PMAX approach was included in its formulation. Used as a diagnostic tool, the model suggests that the surface mass balance for the period 29 April 2004 to 23 April 2005 was negative (-318 mm w.e.).

  4. Molecular Markers in the Quelccaya Ice Cap, Peru Describe 20th Century Biomass Burning Variability

    Science.gov (United States)

    Makou, M. C.; Thompson, L. G.; Eglinton, T. I.; Montluçon, D. B.

    2007-12-01

    Organic geochemical analytical methods were applied to Andean ice core samples, resulting in a multi- molecular biomass burning record spanning 1915 to 2001 AD. The Quelccaya Ice Cap in Peru is situated on the eastern flank of the Andes at 14°S and is well situated to receive aeolian inputs of organic matter derived from Amazonian forest fire events. Compounds of interest, which occur in trace quantities in ice, were recovered by stir bar sorptive extraction and analyzed by gas chromatography/time-of-flight mass spectrometry coupled with thermal desorption. These methods permitted identification and quantitation of numerous biomarkers in sample volumes of as little as 10 ml. At least one wet and dry season sample was analyzed for every year. Observed biomarkers that may be derived from vegetation fires include several polycyclic aromatic hydrocarbons (PAHs), atraric acid, 2-ethylhexyl p-methoxycinnamate, and a range of other aromatic compounds. Abrupt changes in compound abundances were superimposed on decadal variability. Systematic offsets between wet and dry season abundances were not observed, suggesting that the biomass burning signal is not biased by seasonal depositional effects, such as dust delivery. Inputs likely reflect a combination of sources from anthropogenic burning of the Amazon rainforest as well as natural fires related to aridity, and include both high and low elevation vegetation. These compounds and techniques can be applied to older ice in this and other core locations as an independent estimate of aridity.

  5. Early history of high-altitude physiology.

    Science.gov (United States)

    West, John B

    2016-02-01

    High-altitude physiology can be said to have begun in 1644 when Torricelli described the first mercury barometer and wrote the immortal words "We live submerged at the bottom of an ocean of the element air." Interestingly, the notion of atmospheric pressure had eluded his teacher, the great Galileo. Blaise Pascal was responsible for describing the fall in pressure with increasing altitude, and Otto von Guericke gave a dramatic demonstration of the enormous force that could be developed by atmospheric pressure. Robert Boyle learned of Guericke's experiment and, with Robert Hooke, constructed the first air pump that allowed small animals to be exposed to a low pressure. Hooke also constructed a small low-pressure chamber and exposed himself to a simulated altitude of about 2400 meters. With the advent of ballooning, humans were rapidly exposed to very low pressures, sometimes with tragic results. For example, the French balloon, Zénith, rose to over 8000 m, and two of the three aeronauts succumbed to the hypoxia. Paul Bert was the first person to clearly state that the deleterious effects of high altitude were caused by the low partial pressure of oxygen (PO2), and later research was accelerated by high-altitude stations and expeditions to high altitude. © 2015 New York Academy of Sciences.

  6. High Altitude Launch for a Practical SSTO

    Science.gov (United States)

    Landis, Geoffrey A.; Denis, Vincent

    2003-01-01

    Existing engineering materials allow the constuction of towers to heights of many kilometers. Orbital launch from a high altitude has significant advantages over sea-level launch due to the reduced atmospheric pressure, resulting in lower atmospheric drag on the vehicle and allowing higher rocket engine performance. High-altitude launch sites are particularly advantageous for single-stage to orbit (SSTO) vehicles, where the payload is typically 2% of the initial launch mass. An earlier paper enumerated some of the advantages of high altitude launch of SSTO vehicles. In this paper, we calculate launch trajectories for a candidate SSTO vehicle, and calculate the advantage of launch at launch altitudes 5 to 25 kilometer altitudes above sea level. The performance increase can be directly translated into increased payload capability to orbit, ranging from 5 to 20% increase in the mass to orbit. For a candidate vehicle with an initial payload fraction of 2% of gross lift-off weight, this corresponds to 31% increase in payload (for 5-km launch altitude) to 122% additional payload (for 25-km launch altitude).

  7. Ocular morbidity among porters at high altitudes.

    Science.gov (United States)

    Gnyawali, Subodh; Shrestha, Gauri Shankar; Khanal, Safal; Dennis, Talisa; Spencer, John C

    2017-01-01

    High altitude, often characterized by settings over 2400m, can be detrimental to the human body and pose a significant risk to ocular health. Reports concerning various ocular morbidities occurring as a consequence of high altitude are limited in the current literature. This study was aimed at evaluating the ocular health of porters working at high altitudesof Himalayas in Nepal. A mobile eye clinic was set up in Ghat and patient data were collected from its out- patient unit by a team of seven optometrists which was run for five days. Ghat is a small village in north-eastern Nepal, located at 2860 m altitude. Travellers walking through the trekking route were invited to get their eyes checked at the clinic. Comprehensive ocular examinations were performed, including visual acuities, objective and subjective refraction, anterior and posterior segment evaluations, and intraocular pressure measurements; blood pressure and blood glucose levels were also measured as required. Ocular therapeutics, prescription glasses, sunglasses and ocular health referrals were provided free of cost as necessary. A total of 1890 people visited the eye clinic, among which 57.4% (n=1084) were porters. Almost half of the porters had an ocular morbidity. Correctable refractive error was most prevalent, with other ocular health-related complications, including dry eye disease, infectious disorders, glaucoma and cataract. Proper provision of regular and effective eye care services should be made more available for those residing at these high altitudes in Nepal. © NEPjOPH.

  8. Can High Altitude Influence Cytokines and Sleep?

    Directory of Open Access Journals (Sweden)

    Valdir de Aquino Lemos

    2013-01-01

    Full Text Available The number of persons who relocate to regions of high altitude for work, pleasure, sport, or residence increases every year. It is known that the reduced supply of oxygen (O2 induced by acute or chronic increases in altitude stimulates the body to adapt to new metabolic challenges imposed by hypoxia. Sleep can suffer partial fragmentation because of the exposure to high altitudes, and these changes have been described as one of the responsible factors for the many consequences at high altitudes. We conducted a review of the literature during the period from 1987 to 2012. This work explored the relationships among inflammation, hypoxia and sleep in the period of adaptation and examined a novel mechanism that might explain the harmful effects of altitude on sleep, involving increased Interleukin-1 beta (IL-1β, Interleukin-6 (IL-6, and tumor necrosis factor-alpha (TNF-α production from several tissues and cells, such as leukocytes and cells from skeletal muscle and brain.

  9. Can High Altitude Influence Cytokines and Sleep?

    Science.gov (United States)

    de Aquino Lemos, Valdir; dos Santos, Ronaldo Vagner Thomatieli; Lira, Fabio Santos; Rodrigues, Bruno; Tufik, Sergio; de Mello, Marco Tulio

    2013-01-01

    The number of persons who relocate to regions of high altitude for work, pleasure, sport, or residence increases every year. It is known that the reduced supply of oxygen (O2) induced by acute or chronic increases in altitude stimulates the body to adapt to new metabolic challenges imposed by hypoxia. Sleep can suffer partial fragmentation because of the exposure to high altitudes, and these changes have been described as one of the responsible factors for the many consequences at high altitudes. We conducted a review of the literature during the period from 1987 to 2012. This work explored the relationships among inflammation, hypoxia and sleep in the period of adaptation and examined a novel mechanism that might explain the harmful effects of altitude on sleep, involving increased Interleukin-1 beta (IL-1β), Interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-α) production from several tissues and cells, such as leukocytes and cells from skeletal muscle and brain. PMID:23690660

  10. Variability of Seasonal CO2 Ice Caps on Mars for Mars Years 26 through 29

    Science.gov (United States)

    Feldman, W. C.; Maurice, S.; Prettyman, T. H.

    2011-12-01

    We have developed an improved thermal, epithermal, and fast neutron counting-rate time series data of the Mars Odyssey Neutron Spectrometer (MONS), optimized to greatly reduce both statistical and systematic uncertainties. This new data set was applied to study temporal and spatial distributions of the growth, decay, and maximum amount of precipitated CO2 ice during Martian years (MY) 26, 27, 28, and 29. For this study, we concentrate on the epithermal counting rate detected using the down-looking prism (P1) of MONS, and a combination of the epithermal and thermal counting rate detected by the forward-looking sensor (P2) of MONS. Although the energy range of neutrons detected by P2 covers both the thermal and epithermal range, it is heavily weighted to the thermal range. We find that the variance of the maximum epithermal counting rate is remarkably small over both north and south seasonal caps, varying by less than 3% over the four-year period. In contrast, although the maximum P2 counting rate over both poles is sensibly the same within error bars (about 2%) during the first three years, it drops by 18% over the north pole and 8% over the south pole during MY 29. The most-likely explanation of this drop is that abundances of the non-condensable gases N2 and Ar, are unusually enhanced during MY 29. Movies were also made of maps of the growth and decay of P2 counting rates summed over the first three years of these data. Careful inspection shows that both the growth and decay in the north were cylindrically symmetric, centered near the geographic north pole. In contrast, both the growth and decay of CO2 buildup in the south were skewed off the geographic pole to the center of the CO2 residual cap, and contained a small, but definitely distinct ring-like annular enhancement centered at a latitude of about 83.5° S spread over a longitude range that extends between about -35° and +35° E. This arc runs parallel to, and overlays, the very steep drop in altitude from

  11. Pathology of high altitude pulmonary oedema

    International Nuclear Information System (INIS)

    Saleem, N.

    2014-01-01

    Objective: To describe autopsy findings in fatal cases of high altitude pulmonary oedema. Study Design: Descriptive study. Place and Duration of Study: The study was carried out between 1999 and 2002 at an army field medical unit in Baltistan, Armed Forces Institute of Pathology, Rawalpindi and Army Medical College, Rawalpindi, Pakistan. Patients and Methods:Autopsies were performed in 17 fatal cases of High Altitude Pulmonary Edema (HAPE) occurring among soldiers serving in Siachen. Results:All cases were males with a mean age of 26.8 years (19-35). The mean altitude at which HAPE occurred was 5192 meters (2895-6492), and the mean duration of stay at these altitudes was 15.3 days (1-30). Eleven individuals had undergone proper acclimatization. The commonest clinical findings were cough (70%), dyspnoea (53%), nausea (47%), headache (41%), vomiting (35%), chest pain (35%) and tightness in chest (24%). Cyanosis and frothy secretions in the nostrils and mouth were present in all but one case. Mean combined weight of lungs was 1470 grams (1070-1810). There was marked congestion of outer and cut surfaces. Interstitial oedema was present in all cases. RBCs and leukocyte infiltrates were seen in 13 and alveolar hyaline membranes in 9 cases. Thrombi were seen in 2 cases. Cerebral oedema was present in 9 cases. Conclusion:HAPE can occur after more than two weeks of stay at high altitudes despite proper acclimatization. Concomitant cerebral oedema is frequently present. Our autopsy findings are consistent with what has been reported previously. (author)

  12. Recent mass balance of the Purogangri Ice Cap, central Tibetan Plateau, by means of differential X-band SAR interferometry

    Directory of Open Access Journals (Sweden)

    N. Neckel

    2013-10-01

    Full Text Available Due to their remoteness, altitude and harsh climatic conditions, little is known about the glaciological parameters of ice caps on the Tibetan Plateau. This study presents a geodetic mass balance estimate of the Purogangri Ice Cap, Tibet's largest ice field between 2000 and 2012. We utilized data from the actual TerraSAR-X mission and its add-on for digital elevation measurements and compared it with elevation data from the Shuttle Radar Topography Mission. The employed data sets are ideal for this approach as both data sets were acquired at X-band at nearly the same time of the year and are available at a fine grid spacing. In order to derive surface elevation changes we employed two different methods. The first method is based on differential synthetic radar interferometry while the second method uses common DEM differencing. Both approaches revealed a slightly negative mass budget of −44 ± 15 and −38 ± 23 mm w.eq. a−1 (millimeter water equivalent respectively. A slightly negative trend of −0.15 ± 0.01 km2 a−1 in glacier extent was found for the same time period employing a time series of Landsat data. Overall, our results show an almost balanced mass budget for the studied time period. Additionally, we detected one continuously advancing glacier tongue in the eastern part of the ice cap.

  13. CAMEX-4 ER-2 HIGH ALTITUDE DROPSONDE V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The CAMEX-4 ER-2 High Altitude Dropsonde dataset was collected by the ER-2 High Altitude Dropsonde System (EHAD), which used dropwinsondes fitted with Global...

  14. HIGH ALTITUDES EFFECTS ON HEMATOLOGIC BLOOD PARAMETERS

    Directory of Open Access Journals (Sweden)

    Hasim Rushiti

    2015-05-01

    Full Text Available The approach and the objective of this experiment are consistent with the determination of changes of blood parameters after the stay of the students at an altitude of 1800-2300 meters, for a ten-day long ski course. In this paper are included a total of 64 students of the Faculty of Sport Sciences in Prishtina, of the age group of 19-25 (the average age is 21. All students previously have undergone a medical check for TA, arterial pulse and respiratory rate. In particular, the health situation is of subjects was examined, then, all students, at the same time, gave blood for analysis. In this experiment, three main hematologic parameters were taken in consideration: such as hemoglobin, hematocrit and red blood cells. The same analyses were carried out after the 10-day stay at a high altitude. The results of the experiment have shown significant changes after the ten-day stay at high altitude, despite the previous results that show changes only after the twenty-day stay in such elevations.

  15. Peruvian Tropical Glacier May Survive Longer Than Previously Thought: Landsat Image Analysis of Nevado Coropuna Ice Cap, Peru

    Science.gov (United States)

    Kochtitzky, W. H.; Edwards, B. R.; Marino, J.; Manrique, N.

    2015-12-01

    Nevado Coropuna is a large volcanic complex in southern Peru (15.56°S, 72.62°N; 6,425 m). The complex is approximately 12 km east-west and 8 km north-south with elevation from ~4,500 m at the base to over 6,000 m at the highest points. This ice cap is the largest hosted by a volcano in the tropics, and one of the ten biggest ice masses in the tropics. Previous workers have predicted that the Coropuna ice cap will completely melt by 2050. We present a new analysis of historic satellite imagery to test this hypothesis. In this study, ice and snow are classified based on unique spectral signatures including spectral band thresholds, Normalized Difference Snow Index, and Band 4/5 ratio. Landsat scenes (L2, 4, 5, 7, and 8) from 1975 to present in addition to one SPOT scene (2013) are used. Previous workers used images from June and July, which are peak snow periods in southern Peru, leading to overestimates of ice area. This study uses November and December images when snow is at an annual minimum. Annual equilibrium line altitudes are calculated for each end of year image (November/December). The glaciers of Nevado Coropuna were found to be shrinking at ~0.5 km2/yr, which is ~1/3 the rate previously published. In this study, SPOT (1.5 m resolution) and Landsat 7 ETM scenes from November 23 and 26, 2013 respectively were used to calibrate the spectral band threshold classification. While this study suggests that the ice cap of Coropuna will persist until 2100 given current rates, water quantity and security remains a concern for Peruvian agriculture. Coropuna is an active volcano, so it poses great risk to surrounding inhabitants from lahars, flooding, and debris avalanches. Our new data suggest that these will continue to be risks late into this century.

  16. The future sea-level rise contribution of Greenland’s glaciers and ice caps

    DEFF Research Database (Denmark)

    Machguth, H.; Rastner, P.; Bolch, T.

    2013-01-01

    We calculate the future sea-level rise contribution from the surface mass balance of all of Greenland's glaciers and ice caps (GICs, ~90 000 km2) using a simplified energy balance model which is driven by three future climate scenarios from the regional climate models HIRHAM5, RACMO2 and MAR...... experiments suggest that mass loss could be higher by 20–30% if a strong lowering of the surface albedo were to take place in the future. It is shown that the sea-level rise contribution from the north-easterly regions of Greenland is reduced by increasing precipitation while mass loss in the southern half...... feedback mechanisms are considered. The mass loss of all GICs by 2098 is calculated to be 2016 ± 129 Gt (HIRHAM5 forcing), 2584 ± 109 Gt (RACMO2) and 3907 ± 108 Gt (MAR). This corresponds to a total contribution to sea-level rise of 5.8 ± 0.4, 7.4 ± 0.3 and 11.2 ± 0.3 mm, respectively. Sensitivity...

  17. Differences in Bacterial Diversity and Communities Between Glacial Snow and Glacial Soil on the Chongce Ice Cap, West Kunlun Mountains.

    Science.gov (United States)

    Yang, Guang Li; Hou, Shu Gui; Le Baoge, Ri; Li, Zhi Guo; Xu, Hao; Liu, Ya Ping; Du, Wen Tao; Liu, Yong Qin

    2016-11-04

    A detailed understanding of microbial ecology in different supraglacial habitats is important due to the unprecedented speed of glacier retreat. Differences in bacterial diversity and community structure between glacial snow and glacial soil on the Chongce Ice Cap were assessed using 454 pyrosequencing. Based on rarefaction curves, Chao1, ACE, and Shannon indices, we found that bacterial diversity in glacial snow was lower than that in glacial soil. Principal coordinate analysis (PCoA) and heatmap analysis indicated that there were major differences in bacterial communities between glacial snow and glacial soil. Most bacteria were different between the two habitats; however, there were some common bacteria shared between glacial snow and glacial soil. Some rare or functional bacterial resources were also present in the Chongce Ice Cap. These findings provide a preliminary understanding of the shifts in bacterial diversity and communities from glacial snow to glacial soil after the melting and inflow of glacial snow into glacial soil.

  18. High-Altitude Cirrus Clouds and Climate

    Indian Academy of Sciences (India)

    2002-12-03

    , thunder or lightning, rainbows or halos. A cloud is a visible aggregate of tiny water droplets or ice crystals suspended in the air. Most clouds result from cooling due to lifting of moisture containing air. Those associated with ...

  19. The future sea-level rise contribution of Greenland’s glaciers and ice caps

    International Nuclear Information System (INIS)

    Machguth, H; Rastner, P; Bolch, T; Mölg, N; Sørensen, L Sandberg; Aðalgeirsdottir, G; Van Angelen, J H; Van den Broeke, M R; Fettweis, X

    2013-01-01

    We calculate the future sea-level rise contribution from the surface mass balance of all of Greenland’s glaciers and ice caps (GICs, ∼90 000 km 2 ) using a simplified energy balance model which is driven by three future climate scenarios from the regional climate models HIRHAM5, RACMO2 and MAR. Glacier extent and surface elevation are modified during the mass balance model runs according to a glacier retreat parameterization. Mass balance and glacier surface change are both calculated on a 250 m resolution digital elevation model yielding a high level of detail and ensuring that important feedback mechanisms are considered. The mass loss of all GICs by 2098 is calculated to be 2016 ± 129 Gt (HIRHAM5 forcing), 2584 ± 109 Gt (RACMO2) and 3907 ± 108 Gt (MAR). This corresponds to a total contribution to sea-level rise of 5.8 ± 0.4, 7.4 ± 0.3 and 11.2 ± 0.3 mm, respectively. Sensitivity experiments suggest that mass loss could be higher by 20–30% if a strong lowering of the surface albedo were to take place in the future. It is shown that the sea-level rise contribution from the north-easterly regions of Greenland is reduced by increasing precipitation while mass loss in the southern half of Greenland is dominated by steadily decreasing summer mass balances. In addition we observe glaciers in the north-eastern part of Greenland changing their characteristics towards greater activity and mass turnover. (letter)

  20. Climate Changes Documented in Ice Core Records from Third Pole Glaciers, with Emphasis on the Guliya Ice Cap in the Western Kunlun Mountains over the Last 100 Years

    Science.gov (United States)

    Thompson, L. G.; Yao, T.; Beaudon, E.; Mosley-Thompson, E.; Davis, M. E.; Kenny, D. V.; Lin, P. N.

    2016-12-01

    The Third Pole (TP) is a rapidly warming region containing 100,000 km2 of ice cover that collectively holds one of Earth's largest stores of freshwater that feeds Asia's largest rivers and helps sustain 1.5 billion people. Information on the accelerating warming in the region, its impact on the glaciers and subsequently on future water resources is urgently needed to guide mitigation and adaptation policies. Ice core histories collected over the last three decades across the TP demonstrate its climatic complexity and diversity. Here we present preliminary results from the flagship project of the Third Pole Environment Program, the 2015 Sino-American cooperative ice core drilling of the Guliya ice cap in the Kunlun Mountains in the western TP near the northern limit of the region influenced by the southwest monsoon. Three ice cores, each 51 meters in length, were recovered from the summit ( 6700 masl) while two deeper cores, one to bedrock ( 310 meters), were recovered from the plateau ( 6200 masl). Across the ice cap the net balance (accumulation) has increased annually by 2.3 cm of water equivalent from 1963-1992 to 1992-2015, and average oxygen isotopic ratios (δ18O) have enriched by 2‰. This contrasts with the recent ablation on the Naimona'nyi glacier located 540 km south of Guliya in the western Himalaya. Borehole temperatures in 2015 on the Guliya plateau have warmed substantially in the upper 30 meters of the ice compared to temperatures in 1992, when the first deep-drilling of the Guliya plateau was conducted. Compared with glaciers in the northern and western TP, the Himalayan ice fields are more sensitive to both fluctuations in the South Asian Monsoon and rising temperatures in the region. We examine the climatic changes of the last century preserved in ice core records from sites throughout the TP and compare them with those reconstructed for earlier warm epochs, such as the Medieval Climate Anomaly ( 950-1250 AD), the early Holocene "Hypsithermal

  1. Modelling the surface mass balance of the Greenland ice sheet and neighbouring ice caps : A dynamical and statistical downscaling approach

    NARCIS (Netherlands)

    Noël, B.P.Y.

    2018-01-01

    The Greenland ice sheet (GrIS) is the world’s second largest ice mass, storing about one tenth of the Earth’s freshwater. If totally melted, global sea level would rise by 7.4 m, affecting low-lying regions worldwide. Since the mid-1990s, increased atmospheric and oceanic temperatures have

  2. Hemoglobin and testosterone: importance on high altitude acclimatization and adaptation

    OpenAIRE

    Gonzales, Gustavo F.; Jefe de la Unidad de Reproducción, Instituto de Investigaciones de la Altura y Jefe del Laboratorio de Endocrinología y Reproducción, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia. Doctor en Medicina y Doctor en Ciencias. Especialista en Endocrinología.

    2011-01-01

    The different types of response mechanisms that the organism uses when exposed to hypoxia include accommodation, acclimatization and adaptation. Accommodation is the initial response to acute exposure to high altitude hypoxia and is characterized by an increase in ventilation and heart rate. Acclimatization is observed in individuals temporarily exposed to high altitude, and to some extent, it enables them to tolerate the high altitudes. In this phase, erythropoiesis is increased, resulti...

  3. Aspirated Compressors for High Altitude Engines, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Aurora Flight Sciences proposes to incorporate aspirated compressor technology into a high altitude, long endurance (HALE) concept engine. Aspiration has been proven...

  4. High Altitude Warfare: The Kargil Conflict and the Future

    National Research Council Canada - National Science Library

    Acosta, Marcus

    2003-01-01

    The unique combination of thin air, freezing temperatures, and mountainous terrain that forms the high altitude environment has resisted advances in military technology for centuries, The emergence...

  5. Temporal constraints on future accumulation-area loss of a major Arctic ice cap due to climate change (Vestfonna, Svalbard).

    Science.gov (United States)

    Möller, Marco; Schneider, Christoph

    2015-01-28

    Arctic glaciers and ice caps are major contributors to past, present and future sea-level fluctuations. Continued global warming may eventually lead to the equilibrium line altitudes of these ice masses rising above their highest points, triggering unstoppable downwasting. This may feed future sea-level rise considerably. We here present projections for the timing of equilibrium-line loss at the major Arctic ice cap Vestfonna, Svalbard. The projections are based on spatially distributed climatic mass balance modelling driven by the outputs of multiple climate models from the Coupled Model Intercomparison Project Phase 5 (CMIP5) forced by the Representative Concentration Pathways (RCPs) 2.6, 4.5, 6.0 and 8.5. Results indicate strongly decreasing climatic mass balances over the 21(st) century for all RCPs considered. Glacier-wide mass-balance rates will drop down to -4 m a(-1) w.e. (water equivalent) at a maximum. The date at which the equilibrium line rises above the summit of Vestfonna (630 m above sea level) is calculated to range between 2040 and 2150, depending on scenario.

  6. High altitude pulmonary edema among "Amarnath Yatris"

    Directory of Open Access Journals (Sweden)

    Parvaiz A Koul

    2013-01-01

    Full Text Available Background: Annual pilgrimage (Yatra to the cave shrine of Shri Amarnath Ji′ is a holy ritual among the Hindu devotees of Lord Shiva. Located in the Himalayan Mountain Range (altitude 13,000 ft in south Kashmir, the shrine is visited by thousands of devotees and altitude sickness is reportedly common. Materials and Methods: More than 600,000 pilgrims visited the cave shrine in 2011 and 2012 with 239 recorded deaths. Thirty one patients with suspected altitude sickness were referred from medical centers en-route the cave to Sher-i-Kashmir Institute of Medical Sciences, a tertiary-care center in capital Srinagar (5,000 ft. The clinical features and the response to treatment were recorded. Results: Thirty-one patients (all lowlanders, 19 male; age 18-60 years, median 41 had presented with acute onset breathlessness of 1-4 days (median 1.9 d starting within 12-24 h of a rapid ascent; accompanied by cough (68%, headache (8%, dizziness and nausea (65%. Sixteen patients had associated encephalopathy. Clinical features on admission included tachypnea ( n = 31, tachycardia ( n = 23, bilateral chest rales ( n = 29, cyanosis ( n = 22 and grade 2-4 encephalopathy. Hypoxemia was demonstrable in 24 cases and bilateral infiltrates on radiologic imaging in 29. Ten patients had evidence of high-altitude cerebral edema. All patients were managed with oxygen, steroids, nifedipine, sildenafil and other supportive measures including invasive ventilation ( n = 3. Three patients died due to multiorgan dysfunction. Conclusions: Altitude sickness is common among Amaranath Yatris from the plains and appropriate educational strategies should be invoked for prevention and prompt treatment.

  7. Oxidative stress and the high altitude environment

    Directory of Open Access Journals (Sweden)

    Jakub Krzeszowiak

    2013-03-01

    Full Text Available In the recent years there has been considerable interest in mountain sports, including mountaineering, owing to the general availability of climbing clothing and equipment as well trainings and professional literature. This raised a new question for the environmental and mountain medicine: Is mountaineering harmful to health? Potential hazards include the conditions existing in the alpine environment, i.e. lower atmospheric pressure leading to the development of hypobaric hypoxia, extreme physical effort, increased UV radiation, lack of access to fresh food, and mental stress. A reasonable measure of harmfulness of these factors is to determine the increase in the level of oxidative stress. Alpine environment can stimulate the antioxidant enzyme system but under specific circumstances it may exceed its capabilities with simultaneous consumption of low-molecular antioxidants resulting in increased generation of reactive oxygen species (ROS. This situation is referred to as oxidative stress. Rapid and uncontrolled proliferation of reactive oxygen species leads to a number of adverse changes, resulting in the above-average damage to the lipid structures of cell membranes (peroxidation, proteins (denaturation, and nucleic acids. Such situation within the human body cannot take place without resultant systemic consequences. This explains the malaise of people returning from high altitude and a marked decrease in their physical fitness. In addition, a theory is put forward that the increase in the level of oxidative stress is one of the factors responsible for the onset of acute mountain sickness (AMS. However, such statement requires further investigation because the currently available literature is inconclusive. This article presents the causes and effects of development of oxidative stress in the high mountains.

  8. A Chronology of Late-Glacial and Holocene Advances of Quelccaya Ice Cap, Peru, Based on 10Be and Radiocarbon Dating

    Science.gov (United States)

    Kelly, M. A.; Lowell, T. V.; Schaefer, J. M.

    2007-12-01

    The Quelccaya Ice Cap region in the southeastern Peruvian Andes (~13-14°S latitude) is a key location for the development of late-glacial and Holocene terrestrial paleoclimate records in the tropics. We present a chronology of past extents of Quelccaya Ice Cap based on ~thirty internally consistent 10Be dates of boulders on moraines and bedrock as well as twenty radiocarbon dates of organic material associated with moraines. Based on results from both dating methods, we suggest that significant advances of Quelccaya Ice Cap occurred during late-glacial time, at ~12,700-11,400 yr BP, and during Late Holocene time ~400-300 yr BP. Radiocarbon dating of organic material associated with moraines provides maximum and minimum ages for ice advances and recessions, respectively, thus providing an independent check on 10Be dates of boulders on moraines. The opportunity to use both 10Be and radiocarbon dating makes the Quelccaya Ice Cap region a potentially important low-latitude calibration site for production rates of cosmogenic nuclides. Our radiocarbon chronology provides a tighter constraint on maximum ages of late-glacial and Late Holocene ice advances. Upcoming field research will obtain organic material for radiocarbon dating to improve minimum age constrains for late-glacial and Late Holocene ice recessions.

  9. An extremely high altitude plume seen at Mars morning terminator

    Science.gov (United States)

    Sanchez-Lavega, Agustin; Garcia-Muñoz, Antonio; Garcia-Melendo, Enrique; Perez-Hoyos, Santiago; Gomez-Forrellad, Josep M.; Pellier, Christophe; Delcroix, Marc; Lopez-Valverde, Miguel Angel; Gonzalez-Galindo, Francisco; Jaeschke, Wayne; Parker, Donald C.; Phillips, James H.; Peach, Damian

    2014-11-01

    We report the occurrence in March and April 2012 of two bright very high altitude plumes at the Martian terminator at 250 km or more above the surface, thus well into the ionosphere and bordering on the exosphere. They were located at about 195 deg West longitude and -45 deg latitude (at Terra Cimmeria) and lasted for about 10 days. The features showed day-to-day variability, and were seen at the morning terminator but not at the evening limb, which indicates rapid evolution in less than 10 hours and a cyclic behavior. Photometric measurements are used to explore two possible scenarios to explain their nature. If the phenomenon is due to suspended particles (dust, CO2 or H2O ice clouds) reflecting solar radiation, the mean size is about 0.1 microns with a nadir optical depth > 0.06. Alternatively, the plume could be auroral emission above a region with a strong magnetic anomaly and where aurora has previously been detected. Importantly, both explanations defy our current understanding of the Mars upper atmosphere.AcknowledgementsThis work was supported by the Spanish MINECO projects AYA2012-36666 with FEDER support, CONSOLIDER program ASTROMOL CSD2009-00038 and AYA2011-30613-CO2-1. Grupos Gobierno Vasco IT765-13 and UPV/EHU UFI11/55.

  10. Holocene glacier and climate variations in Vestfirðir, Iceland, from the modeling of Drangajökull ice cap

    Science.gov (United States)

    Anderson, Leif S.; Flowers, Gwenn E.; Jarosch, Alexander H.; Aðalgeirsdóttir, Guðfinna Th; Geirsdóttir, Áslaug; Miller, Gifford H.; Harning, David J.; Thorsteinsson, Thorsteinn; Magnússon, Eyjólfur; Pálsson, Finnur

    2018-06-01

    Drangajökull is a maritime ice cap located in northwest (Vestfirðir) Iceland. Drangajökull's evolution is therefore closely linked to atmospheric and ocean variability. In order to better constrain the Holocene climate and glacier history of Vestfirðir we model the past evolution of Drangajökull ice cap. Simulations from 10 ka to present are forced by general circulation model output, ice-core-based temperature reconstructions, and sea-surface temperature reconstructions. Based on these 10-thousand year simulations, Drangajökull did not persist through the Holocene. We estimate that air temperatures were 2.5-3.0 °C higher during the Holocene Thermal Maximum than the local 1960-1990 average. Simulations support Drangajökull's late Holocene inception between 2 and 1 ka, though intermittent ice likely occupied cirques as early as 2.6 ka. Drangajökull is primarily a Little Ice Age ice cap: it expanded between 1300 and 1750 CE, with the most rapid growth occurring between 1600 and 1750 CE. The maximum Holocene extent of Drangajökull occurred between 1700 and 1925 CE, despite the lowest late Holocene temperatures, occurring between 1650 and 1720 CE. Between 1700 and 1925 CE temperatures were likely 0.6-0.8 °C lower than the 1950-2015 reference temperature. The modern equilibrium line altitude (ELA) is bracketed by topographic thresholds: a 1 °C temperature increase from the modern ELA would eliminate the ice cap's accumulation area, while a reduction of 0.5 °C would lead to the rapid expansion of the ice cap across Vestfirðir. The proximity of Drangajökull to topographic thresholds may explain its late inception and rapid expansion during the Little Ice Age.

  11. [Hemoglobin and testosterone: importance on high altitude acclimatization and adaptation].

    Science.gov (United States)

    Gonzales, Gustavo F

    2011-03-01

    The different types of response mechanisms that the organism uses when exposed to hypoxia include accommodation, acclimatization and adaptation. Accommodation is the initial response to acute exposure to high altitude hypoxia and is characterized by an increase in ventilation and heart rate. Acclimatization is observed in individuals temporarily exposed to high altitude, and to some extent, it enables them to tolerate the high altitudes. In this phase, erythropoiesis is increased, resulting in higher hemoglobin and hematocrit levels to improve oxygen delivery capacity. Adaptation is the process of natural acclimatization where genetical variations and acclimatization play a role in allowing subjects to live without any difficulties at high altitudes. Testosterone is a hormone that regulates erythropoiesis and ventilation and could be associated to the processes of acclimatization and adaptation to high altitude. Excessive erythrocytosis, which leads to chronic mountain sickness, is caused by low arterial oxygen saturation, ventilatory inefficiency and reduced ventilatory response to hypoxia. Testosterone increases during acute exposure to high altitude and also in natives at high altitude with excessive erythrocytosis. Results of current research allow us to conclude that increase in serum testosterone and hemoglobin is adequate for acclimatization, as they improve oxygen transport, but not for high altitude adaptation, since high serum testosterone levels are associated to excessive erythrocytosis.

  12. Acute high-altitude illness | Hofmeyr | South African Medical Journal

    African Journals Online (AJOL)

    A substantial proportion of South Africa (SA)'s population lives at high altitude (>1 500 m), and many travel to very high altitudes (>3 500 m) for tourism, business, recreation or religious pilgrimages every year. Despite this, knowledge of acute altitude illnesses is poor among SA doctors. At altitude, the decreasing ambient ...

  13. Recent ice cap snowmelt in Russian High Arctic and anti-correlation with late summer sea ice extent

    International Nuclear Information System (INIS)

    Zhao, Meng; Ramage, Joan; Semmens, Kathryn; Obleitner, Friedrich

    2014-01-01

    Glacier surface melt dynamics throughout Novaya Zemlya (NovZ) and Severnaya Zemlya (SevZ) serve as a good indicator of ice mass ablation and regional climate change in the Russian High Arctic. Here we report trends of surface melt onset date (MOD) and total melt days (TMD) by combining multiple resolution-enhanced active and passive microwave satellite datasets and analyze the TMD correlations with local temperature and regional sea ice extent. The glacier surface snowpack on SevZ melted significantly earlier (−7.3 days/decade) from 1992 to 2012 and significantly longer (7.7 days/decade) from 1995 to 2011. NovZ experienced large interannual variability in MOD, but its annual mean TMD increased. The snowpack melt on NovZ is more sensitive to temperature fluctuations than SevZ in recent decades. After ruling out the regional temperature influence using partial correlation analysis, the TMD on both archipelagoes is statistically anti-correlated with regional late summer sea ice extent, linking land ice snowmelt dynamics to regional sea ice extent variations. (letter)

  14. High-Altitude Illnesses: Physiology, Risk Factors, Prevention, and Treatment

    Directory of Open Access Journals (Sweden)

    Andrew T. Taylor

    2011-01-01

    Full Text Available High-altitude illnesses encompass the pulmonary and cerebral syndromes that occur in non-acclimatized individuals after rapid ascent to high altitude. The most common syndrome is acute mountain sickness (AMS which usually begins within a few hours of ascent and typically consists of headache variably accompanied by loss of appetite, nausea, vomiting, disturbed sleep, fatigue, and dizziness. With millions of travelers journeying to high altitudes every year and sleeping above 2,500 m, acute mountain sickness is a wide-spread clinical condition. Risk factors include home elevation, maximum altitude, sleeping altitude, rate of ascent, latitude, age, gender, physical condition, intensity of exercise, pre-acclimatization, genetic make-up, and pre-existing diseases. At higher altitudes, sleep disturbances may become more profound, mental performance is impaired, and weight loss may occur. If ascent is rapid, acetazolamide can reduce the risk of developing AMS, although a number of high-altitude travelers taking acetazolamide will still develop symptoms. Ibuprofen can be effective for headache. Symptoms can be rapidly relieved by descent, and descent is mandatory, if at all possible, for the management of the potentially fatal syndromes of high-altitude pulmonary and cerebral edema. The purpose of this review is to combine a discussion of specific risk factors, prevention, and treatment options with a summary of the basic physiologic responses to the hypoxia of altitude to provide a context for managing high-altitude illnesses and advising the non-acclimatized high-altitude traveler.

  15. Prediction of future hydrological regimes in poorly gauged high altitude basins: the case study of the upper Indus, Pakistan

    Directory of Open Access Journals (Sweden)

    D. Bocchiola

    2011-07-01

    Full Text Available In the mountain regions of the Hindu Kush, Karakoram and Himalaya (HKH the "third polar ice cap" of our planet, glaciers play the role of "water towers" by providing significant amount of melt water, especially in the dry season, essential for agriculture, drinking purposes, and hydropower production. Recently, most glaciers in the HKH have been retreating and losing mass, mainly due to significant regional warming, thus calling for assessment of future water resources availability for populations down slope. However, hydrology of these high altitude catchments is poorly studied and little understood. Most such catchments are poorly gauged, thus posing major issues in flow prediction therein, and representing in fact typical grounds of application of PUB concepts, where simple and portable hydrological modeling based upon scarce data amount is necessary for water budget estimation, and prediction under climate change conditions. In this preliminarily study, future (2060 hydrological flows in a particular watershed (Shigar river at Shigar, ca. 7000 km2, nested within the upper Indus basin and fed by seasonal melt from major glaciers, are investigated.

    The study is carried out under the umbrella of the SHARE-Paprika project, aiming at evaluating the impact of climate change upon hydrology of the upper Indus river. We set up a minimal hydrological model, tuned against a short series of observed ground climatic data from a number of stations in the area, in situ measured ice ablation data, and remotely sensed snow cover data. The future, locally adjusted, precipitation and temperature fields for the reference decade 2050–2059 from CCSM3 model, available within the IPCC's panel, are then fed to the hydrological model. We adopt four different glaciers' cover scenarios, to test sensitivity to decreased glacierized areas. The projected flow duration curves, and some selected flow descriptors are evaluated. The uncertainty of

  16. High altitude flights in equatorial regions

    Science.gov (United States)

    Redkar, R. T.

    A thorough analysis of balloon flights made from Hyderabad, India (Latitude 17°28'N, Longitude 78°35'E), and other equatorial sites has been made. It has been shown that limited success is expected for flights made from equatorial latitudes with balloons made out of natural colour polyethylene film, since the best known balloon film in the world today viz. Winzen Stratofilm is tested for low temperature brittleness only at -80°C., whereas the tropopause temperatures over equatorial latitudes vary between -80°C and -90°C. The success becomes even more critical when flights are made with heavy payloads and larger balloons particularly at night when in the absence of solar radiation the balloon film becomes more susceptible to low temperature brittle failure. It is recommended that in case of capped balloons longer caps should be used to fully cover the inflated protion of the balloon at the higher level equatorial tropopause. It is also advised that the conditions such as wind shears in the tropopause should be critically studied before launching and a day with the tropopause temperature nearer to -80°C should be chosen. Special care also should be taken while handling the balloon on ground and during launching phase. Properties of Winzen Stratofilm have been critically studied and fresh mandates have been recommended on the basis of limiting values of film stresses which caused balloon failures in the equatorial tropopause. It is also emphasized that the data on such flights is still meagre especially for flights with heavy payloads and larger balloons. It has been also shown that it is safest to use balloons made out of grey coloured film which retains its flexibility with the absorption of solar radiation, the success obtained with such balloons so far being 100%. The drawback, however, is that these balloons cannot be used for night flights. Stratospheric wind regimes over Hyderabad are also discussed with a view to determine the period over which long

  17. Kajian Teknologi High Altitude Platform (HAP [Study of High Altitude Platform (HAP Technology

    Directory of Open Access Journals (Sweden)

    Amry Daulat Gultom

    2016-07-01

    Full Text Available High Altitude Platform (HAP merupakan solusi alternatif untuk mengatasi keterbatasan infrastruktur terestrial maupun satelit. HAP merupakan pesawat ataupun balon udara yang ditempatkan pada ketinggian 20-50 km di atas permukaan bumi. Kelebihan yang utama dari HAP adalah kemudahan dalam penempatan, fleksibilitas, biaya operasionalnya rendah, delay  propagasi rendah, sudut elevasi lebar, cakupan yang luas. Penelitian ini dilakukan untuk mengetahui potensi HAP untuk komunikasi pita lebar dan perkembangannya di Indonesia. Analisis dilakukan secara deskriptif dengan mengolah data literatur yang didapat. Hasil penelitian menunjukkan bahwa di Indonesia terdapat potensi teknologi HAP untuk komunikasi pita lebar dengan lebar pita 2x300 MHz di band 27,9-28,2 GHz dan 31-31,3 GHz. Namun, belum ada peraturan yang mengatur alokasi frekuensi untuk HAP secara khusus di Indonesia.*****High Altitude Platform (HAP has been developed as an alternative solution in order to overcome limitation of terrestrial and satellite communication system. HAP is an aircraft or balloon situated on 20-50 km above the earth. Main advantages of HAP are flexibility in deployment, low propagation delay, wide elevation angle and broad coverage. The research is conducted to gather HAP potential for broadband communication and its development in Indonesia. Analysis is conducted by descriptive analysis from literature study gather. The research result shows that in Indonesia, there is potential of HAP technology for broadband communication with 2x300 MHz bandwidth within 27,9-28,2 GHz and 31-31,3 GHz. Yet, there are no specific regulations managing frequency allocation for HAP in Indonesia.

  18. Additions and corrections to the absorption coefficients of CO2 ice: Applications to the Martian south polar cap

    International Nuclear Information System (INIS)

    Calvin, W.M.

    1990-01-01

    Reflectance spectra of carbon dioxide frosts were calculated using the optical constants provided by Warren (1986) for the wavelength region 2-6 μm. In comparing these calculated spectra to spectra of frosts observed in the laboratory and on the surface of Mars, problems in the optical constants presented by Warren (1986) became apparent. Absorption coefficients for CO 2 ice have been derived using laboratory reflectance measurements and the Hapke (1981) model for calculating diffuse reflectance. This provides approximate values in regions where no data were previously available and indicates where corrections to the compilation by Warren (1986) are required. Using these coefficients to calculate the reflectance of CO 2 ice at varying grain sizes indicates that a typical Mariner polar cap spectrum is dominated by absorptions due to CO 2 frost or ice at grain sizes that are quite large, probably of the order of millimeters to centimeters. There are indications of contamination of water frost or dust, but confirmation will require more precise absorption coefficients for solid CO 2 than can be obtained from the method used here

  19. Ben Macdhui High Altitude Trace Gas and Aerosol Transport Experiment

    CSIR Research Space (South Africa)

    Piketh, SJ

    1999-01-01

    Full Text Available The Ben Macdhui High Altitude Aerosol and Trace Gas Transport Experiment (BHATTEX) was started to characterize the nature and magnitude of atmospheric, aerosol and trace gas transport paths recirculation over and exiting from southern Africa...

  20. Functions and Design Scheme of Tibet High Altitude Test Base

    Institute of Scientific and Technical Information of China (English)

    Yu Yongqing; Guo Jian; Yin Yu; Mao Yan; Li Guangfan; Fan Jianbin; Lu Jiayu; Su Zhiyi; Li Peng; Li Qingfeng; Liao Weiming; Zhou Jun

    2010-01-01

    @@ The functional orientation of the Tibet High Altitude Test Base, subordinated to the State Grid Corporation of China (SGCC), is to serve power transmission projects in high altitude areas, especially to provide technical support for southwestern hydropower delivery projects by UHVDC transmission and Qinghai-Tibet grid interconnection project. This paper presents the matters concerned during siting and planning, functions,design scheme, the main performances and parameters of the test facilities, as well as the tests and research tasks already carried out.

  1. Lake Sediment Records as an Indicator of Holocene Fluctuations of Quelccaya Ice Cap, Peru and Regional Climate

    Science.gov (United States)

    Stroup, J. S.; Kelly, M. A.; Lowell, T. V.; Beal, S. A.; Smith, C. A.; Baranes, H. E.

    2012-12-01

    The past fluctuations of Quelccaya Ice Cap, (QIC; 13°S, 70°W, 5200 m asl) located in the southeastern Peruvian Andes, provide a record of tropical climate since the last glacial-interglacial transition. A detailed surficial geomorphic record of past glacial extents developed over the last several decades (e.g. Mercer and Palacios 1977; Buffen et al. 2009; Kelly et al. 2012 accepted) demonstrates that QIC is a dynamic glacial system. These records show that the ice cap was larger than present and retreating by ~11,500 yr BP, and smaller than present between ~7,000 and ~4,600 yr BP. The most recent advance occurred during the late Holocene (Little Ice Age;LIA), dated with 10Be surface exposure ages (510±90 yrs (n = 8)) (Stroup et al. in prep.). This overrode earlier deposits obscuring a complete Holocene record; we aim to address the gaps in glacial chronology using the sedimentary record archived in lakes. We retrieved two sets cores (8 and 5 m-long) from Laguna Challpacocha (13.91°S, 70.86°W, 5040 m asl), a lake that currently receives meltwater from QIC. Four radiocarbon ages from the cores suggest a continuous record dating to at least ~10,500 cal. yr BP. Variations in magnetic susceptibility, percent organic and inorganic carbon, bulk density, grayscale and X-ray fluorescence chemistry indicate changes in the amount of clastic sediment deposition. We interpret clastic sediments to have been deposited from ice cap meltwater, thus indicating more extensive ice. Clastic sediments compose the top of the core from 4 to 30 cm depth, below there is a sharp transition to organic sediments radiocarbon dated to (500±30 and 550±20 cal. yr BP). The radiocarbon ages are similar to the 10Be dated (LIA) glacial position. At least three other clastic units exist in the core; dating to ~2600-4300, ~4800-7300 and older then ~10,500 cal. yr BP based on a linear age model with four radiocarbon dates. We obtained two, ~4 m long, cores from Laguna Yanacocha (13.95°S,70.87

  2. DLR HABLEG- High Altitude Balloon Launched Experimental Glider

    Science.gov (United States)

    Wlach, S.; Schwarzbauch, M.; Laiacker, M.

    2015-09-01

    The group Flying Robots at the DLR Institute of Robotics and Mechatronics in Oberpfaffenhofen conducts research on solar powered high altitude aircrafts. Due to the high altitude and the almost infinite mission duration, these platforms are also denoted as High Altitude Pseudo-Satellites (HAPS). This paper highlights some aspects of the design, building, integration and testing of a flying experimental platform for high altitudes. This unmanned aircraft, with a wingspan of 3 m and a mass of less than 10 kg, is meant to be launched as a glider from a high altitude balloon in 20 km altitude and shall investigate technologies for future large HAPS platforms. The aerodynamic requirements for high altitude flight included the development of a launch method allowing for a safe transition to horizontal flight from free-fall with low control authority. Due to the harsh environmental conditions in the stratosphere, the integration of electronic components in the airframe is a major effort. For regulatory reasons a reliable and situation dependent flight termination system had to be implemented. In May 2015 a flight campaign was conducted. The mission was a full success demonstrating that stratospheric research flights are feasible with rather small aircrafts.

  3. Mass budget of Queen Elizabeth Islands glaciers and ice caps, Canada, from 1992 to present

    Science.gov (United States)

    Millan, R.; Rignot, E. J.; Mouginot, J.

    2015-12-01

    Recent studies indicate to say that the Canadian Artic Archipelago's mass loss has increased in recent years. However the role of ice dynamics changes in this area is not well known. In this study, we present a comprehensive velocity mapping of the CAA using ALOS/PALSAR, RADARSAT-1, ERS1 and Landsat data between 1992 and 2015. Glaciers speed are calculated using a speckle and feature tracking algorithm.The results reveals that three large marine-terminating glaciers have accelerated significantly after 2010, while most others have slowed down or retreated to a sill to become similar to land-terminating glaciers. By combining the velocities of these glaciers with ice thickness measurements from NASA's Operation IceBridge, we calculate their ice discharge. The fluxes of these glaciers increased significantly since 2000 with a marked increase after 2011. The comparison of ice discharge with the surface mass balance from RACMO-2, shows that these glaciers came out of balance after 2011, which is also a time period where their discharge almost doubled. The analysis of RACMO-2 reveals an increase in runoff between 1970's and today and a precipitation with no significant trend. We digitalize the calving front positions of the glaciers and show an increasing rate retreat since 1976. We conclude that global pattern of velocity changes shows that the mass losses due to surface mass balance will likely going to raise in the coming years and that ice discharge will have a smaller part in the contribution of the CAA to sea level rise.

  4. 10Be dating of late-glacial moraines near the Cordillera Vilcanota and the Quelccaya Ice Cap, Peru

    Science.gov (United States)

    Kelly, M. A.; Thompson, L. G.

    2004-12-01

    The surface exposure method, based on the measurement of cosmogenic 10Be produced in quartz, is applied to determine the age of deposition of glacial moraines near the Cordillera Vilcanota and the Quelccaya Ice Cap (about 13° S, 70° W) in southeastern Peru. These data are useful for examining the timing of past glaciation in the tropical Andes and for comparison with chronologies of glaciation at higher latitudes. The preliminary data set consists of more than ten surface exposure ages. Samples used for dating are from the surfaces of boulders on a set of prominent moraines about four kilometers away from the present ice margins. The age of the moraine set was previously bracketed by radiocarbon dating of peat associated with the glacial deposits. Based on radiocarbon ages, these moraines were formed during the late-glacial period, just prior to the last glacial-interglacial transition. The surface exposure dating method enables the direct dating of the moraines. Surface exposure dates are cross-checked with the previously existing radiocarbon dates and provide a means to improve the chronology of past glaciation in the tropical Andes.

  5. Atmospheric Depositions of Natural and Anthropogenic Aerosols on the Guliya Ice Cap (Northwestern Tibetan Plateau) during the last 340 years

    Science.gov (United States)

    Sierra Hernandez, R.; Gabrielli, P.; Beaudon, E.; Thompson, L. G.; Wegner, A.

    2017-12-01

    Anthropogenic emissions (e.g., greenhouse gases, trace elements (TE) including toxic metals) to the atmosphere have dramatically increased since the Industrial Revolution in the 19th century. High temperature processes such as fossil fuel combustion and pyrometallurgy generate fumes and fine particles (industrial times. Thus, ice core records of TEs from mid- and low-latitudes are needed to assess the spatial and temporal extent and levels of pollution in the environment. Here we present records of 29 TEs spanning the period 1650-1991 CE from the Guliya ice cap in the western Kunlun Mountains, northwest Tibetan Plateau to assess their natural and anthropogenic sources. The Guliya TEs records show two distinct periods with only crustal contributions prior to the 1850s and non-crustal contributions (Pb, Cd, Sb, Zn, Sn) after the 1850s. Enrichments of Pb, Cd, Sb, and Zn in Guliya between 1850 and 1950 can be attributed primarily to coal combustion emissions from western countries (Europe) while regional emissions (fossil fuel combustion, mining/smelting, fertilizers) from Central Asia, and probably from Kashgar in western China, and South Asia (India, Nepal) could be the source of the TE enrichments (Cd, Pb, Sn) observed in Guliya after 1950. This information can be used by modelers to assess pollution transport at local, regional, and global scales and by policy makers to develop strategies and policies to reduce their emissions.

  6. Shilajit: A panacea for high-altitude problems.

    Science.gov (United States)

    Meena, Harsahay; Pandey, H K; Arya, M C; Ahmed, Zakwan

    2010-01-01

    High altitude problems like hypoxia, acute mountain sickness, high altitude cerebral edema, pulmonary edema, insomnia, tiredness, lethargy, lack of appetite, body pain, dementia, and depression may occur when a person or a soldier residing in a lower altitude ascends to high-altitude areas. These problems arise due to low atmospheric pressure, severe cold, high intensity of solar radiation, high wind velocity, and very high fluctuation of day and night temperatures in these regions. These problems may escalate rapidly and may sometimes become life-threatening. Shilajit is a herbomineral drug which is pale-brown to blackish-brown, is composed of a gummy exudate that oozes from the rocks of the Himalayas in the summer months. It contains humus, organic plant materials, and fulvic acid as the main carrier molecules. It actively takes part in the transportation of nutrients into deep tissues and helps to overcome tiredness, lethargy, and chronic fatigue. Shilajit improves the ability to handle high altitudinal stresses and stimulates the immune system. Thus, Shilajit can be given as a supplement to people ascending to high-altitude areas so that it can act as a "health rejuvenator" and help to overcome high-altitude related problems.

  7. Can people with Raynaud's phenomenon travel to high altitude?

    Science.gov (United States)

    Luks, Andrew M; Grissom, Colin K; Jean, Dominique; Swenson, Erik R

    2009-01-01

    To determine whether high altitude travel adversely affects mountain enthusiasts with Raynaud's phenomenon. Volunteers with Raynaud's phenomenon were recruited using announcements disseminated by organizations dedicated to climbing or wilderness travel and Internet discussion boards dedicated to mountain activities to complete an online, anonymous survey. Survey questions addressed demographic variables, aspects of their Raynaud's phenomenon, and features of their mountain activities. Respondents compared experiences with Raynaud's phenomenon between high (>2440 m; 8000 feet) and low elevations and rated agreement with statements concerning their disease and the effects of high altitude. One hundred forty-two people, 98% of whom had primary Raynaud's phenomenon, completed the questionnaire. Respondents spent 5 to 7 days per month at elevations above 2440 m and engaged in 5.4 +/- 2.0 different activities. Eighty-nine percent of respondents engaged in winter sports and only 22% reported changing their mountain activities because of Raynaud's phenomenon. Respondents reported a variety of tactics to prevent and treat Raynaud's attacks, but only 12% used prophylactic medications. Fifteen percent of respondents reported an episode of frostbite following a Raynaud's phenomenon attack at high altitude. There was considerable heterogeneity in participants' perceptions of the frequency, duration, and severity of attacks at high altitude compared to their home elevation. Motivated individuals with primary Raynaud's phenomenon, employing various prevention and treatment strategies, can engage in different activities, including winter sports, at altitudes above 2440 m. Frostbite may be common in this population at high altitude, and care must be taken to prevent its occurrence.

  8. Are macroinvertebrates in high altitude streams affected by oxygen deficiency?

    DEFF Research Database (Denmark)

    Jacobsen, Dean; Rostgaard, S.; Vásconez, J. J.

    2003-01-01

    1. The solubility of oxygen in water increases with decreasing temperature. This has led to a general perception of cold, high mountain streams as more oxygen rich than warmer lowland streams, and that macroinvertebrates inhabiting high altitude streams have had no need to adapt to critical oxygen...... conditions. However, this fails to take into account that oxygen solubility declines with decreasing atmospheric pressure, which may be of importance at high altitudes. 2. Based on samples of macroinvertebrate benthos and in situ measurements of respiratory oxygen demand of macroinvertebrates in small...... the mean weight-specific respiratory rate of macroinvertebrates declined by only 50%, from 400 to 3800 m. We suggest that this disproportionately large gap between availability and demand of oxygen at high altitudes may imply a potential oxygen deficiency for the fauna, and we discuss how oxygen deficiency...

  9. Effects of ascent to high altitude on human antimycobacterial immunity.

    Directory of Open Access Journals (Sweden)

    Sarah Eisen

    Full Text Available Tuberculosis infection, disease and mortality are all less common at high than low altitude and ascent to high altitude was historically recommended for treatment. The immunological and mycobacterial mechanisms underlying the association between altitude and tuberculosis are unclear. We studied the effects of altitude on mycobacteria and antimycobacterial immunity.Antimycobacterial immunity was assayed in 15 healthy adults residing at low altitude before and after they ascended to 3400 meters; and in 47 long-term high-altitude residents. Antimycobacterial immunity was assessed as the extent to which participants' whole blood supported or restricted growth of genetically modified luminescent Bacille Calmette-Guérin (BCG mycobacteria during 96 hours incubation. We developed a simplified whole blood assay that could be used by a technician in a low-technology setting. We used this to compare mycobacterial growth in participants' whole blood versus positive-control culture broth and versus negative-control plasma.Measurements of mycobacterial luminescence predicted the number of mycobacterial colonies cultured six weeks later. At low altitude, mycobacteria grew in blood at similar rates to positive-control culture broth whereas ascent to high altitude was associated with restriction (p ≤ 0.002 of mycobacterial growth to be 4-times less than in culture broth. At low altitude, mycobacteria grew in blood 25-times more than negative-control plasma whereas ascent to high altitude was associated with restriction (p ≤ 0.01 of mycobacterial growth to be only 6-times more than in plasma. There was no evidence of differences in antimycobacterial immunity at high altitude between people who had recently ascended to high altitude versus long-term high-altitude residents.An assay of luminescent mycobacterial growth in whole blood was adapted and found to be feasible in low-resource settings. This demonstrated that ascent to or residence at high altitude was

  10. Rare Particle Searches with the high altitude SLIM experiment

    CERN Document Server

    Balestra, S; Fabbri, F; Giacomelli, G; Giacomelli, R; Giorgini, M; Kumar, A; Manzoor, S; McDonald, J; Margiotta, A; Medinaceli, E; Nogales, J; Patrizii, L; Popa, V; Quereshi, I; Saavedra, O; Sher, G; Shahzad, M; Spurio, M; Ticona, R; Togo, V; Velarde, A; Zanini, A

    2005-01-01

    The search for rare particles in the cosmic radiation remains one of the main aims of non-accelerator particle astrophysics. Experiments at high altitude allow lower mass thresholds with respect to detectors at sea level or underground. The SLIM experiment is a large array of nuclear track detectors located at the Chacaltaya High Altitude Laboratory (5290 m a.s.l.). The preliminary results from the analysis of a part of the first 236 sq.m exposed for more than 3.6 y are here reported. The detector is sensitive to Intermediate Mass Magnetic Monopoles and to SQM nuggets and Q-balls, which are possible Dark Matter candidates.

  11. Preacclimatization in hypoxic chambers for high altitude sojourns.

    Science.gov (United States)

    Küpper, Thomas E A H; Schöffl, Volker

    2010-09-01

    Since hypoxic chambers are more and more available, they are used for preacclimatization to prepare for sojourns at high altitude. Since there are different protocols and the data differ, there is no general consensus about the standard how to perform preacclimatization by simulated altitude. The paper reviews the different types of exposure and focuses on the target groups which may benefit from preacclimatization. Since data about intermittent hypoxia for some hours per day to reduce the incidence of acute mountain sickness differ, it is suggested to perform preacclimatization by sleeping some nights at a simulated altitude which follows the altitude profile of the "gold standard" for high altitude acclimatization.

  12. Analysis of high-altitude de-acclimatization syndrome after exposure to high altitudes: a cluster-randomized controlled trial.

    Science.gov (United States)

    He, Binfeng; Wang, Jianchun; Qian, Guisheng; Hu, Mingdong; Qu, Xinming; Wei, Zhenghua; Li, Jin; Chen, Yan; Chen, Huaping; Zhou, Qiquan; Wang, Guansong

    2013-01-01

    The syndrome of high-altitude de-acclimatization commonly takes place after long-term exposure to high altitudes upon return to low altitudes. The syndrome severely affects the returnee's quality of life. However, little attention has been paid to careful characterization of the syndrome and their underlying mechanisms. Male subjects from Chongqing (n = 67, 180 m) and Kunming (n = 70, 1800 m) visited a high-altitude area (3650 m) about 6 months and then returned to low-altitude. After they came back, all subjects were evaluated for high-altitude de-acclimatization syndrome on the 3(rd), 50(th), and 100(th). Symptom scores, routine blood and blood gas tests, and myocardial zymograms assay were used for observation their syndrome. The results showed that the incidence and severity of symptoms had decreased markedly on the 50(th) and 100(th) days, compared with the 3(rd) day. The symptom scores and incidence of different symptoms were lower among subjects returning to Kunming than among those returning to Chongqing. On the 3(rd) day, RBC, Hb, Hct, CK, CK-MB, and LDH values were significantly lower than values recorded at high altitudes, but they were higher than baseline values. On the 50(th) day, these values were not different from baseline values, but LDH levels did not return to baseline until the 100(th) day. These data show that, subjects who suffered high-altitude de-acclimatization syndrome, the recovery fully processes takes a long time (≥ 100(th) days). The appearance of the syndrome is found to be related to the changes in RBC, Hb, Hct, CK, CK-MB, and LDH levels, which should be caused by reoxygenation after hypoxia.

  13. Timing of Expansions of the Quelccaya Ice Cap, Peru, and Implications for Cosmogenic Nuclide Production Rate Calibration

    Science.gov (United States)

    Lowell, T. V.; Kelly, M. A.; Applegate, P. J.; Smith, C. A.; Phillips, F. M.; Hudson, A. M.

    2010-12-01

    We calibrate the production rate of the cosmogenic nuclide beryllium-10 (10Be) at a low-latitude, high-elevation site, using nuclide concentrations measured in moraine boulders and an independent chronology determined with bracketing radiocarbon dates. The measurement of terrestrial cosmogenic nuclide (TCN) concentrations in earth surface materials has been an important development for understanding a host of earth surface processes. Uncertainty in cosmogenic nuclide production rates has hampered application of this method. Here, we contribute to the estimation of 10Be production rates by reporting both preliminary 10Be concentrations and independent radiocarbon dates from a low latitude, high elevation site. Our study site in the southeastern Peruvian Andes (~13.9°S, 70.9°W, 4850 m asl) is centered on a moraine set, known as the Huancané II moraines, that represents a ~4 km expansion of Quelccaya Ice Cap during late glacial time. At this location, organic material situated both stratigraphically below and above moraines in two adjacent valleys provide material for radiocarbon dating. Based on geomorphic arguments, we correlate results from the two valleys. The timing of ice cap margin advance is bracketed by 13 radiocarbon ages on organic material within the outermost Huancané II moraines that range from 13.6 to 12.5 ka. Two stratigraphic sections upvalley from the moraines yield 6 radiocarbon ages from 11.3 to 12.4 ka, indicating the time of retreat . We computed the probability density function that lies between these two sets of dates, and assign an age of 12.4 ka (+/-???) for the formation of the Huancané II moraines. Calculating beryllium-10 exposure dates from the measured concentrations yield exposure dates that significantly underestimate the independently determined age of the moraine (~8-30%), if existing production rate estimates are used. We suggest that the radiocarbon age for the moraines can be used as a robust independent calibration for 10Be

  14. Inland and Near-Shore Water Profiles Derived from the High-Altitude Multiple Altimeter Beam Experimental Lidar (MABEL)

    Science.gov (United States)

    Jasinski, Michael F.; Stoll, Jeremy D.; Cook, William B.; Ondrusek, Michael; Stengel, Eric; Brunt, Kelly

    2016-01-01

    The Advanced Topographic Laser Altimeter System (ATLAS) on the Ice, Cloud, and Land Elevation Satellite (ICESat-2) mission is a six beam, low energy, high repetition rate, 532-nanometer laser transmitter with photon counting detectors. Although designed primarily for detecting height changes in ice caps, sea ice, and vegetation, the polar-orbiting satellite will observe global surface water during its designed three-year life span, including inland waterbodies, coasts, and open oceans. In preparation for the mission, an ICESat-2 prototype, the Multiple Altimeter Beam Experimental Lidar (MABEL), was built and flown on high-altitude aircraft experiments over a range of inland and near-shore targets. The purpose was to test the ATLAS concept and to provide a database for developing an algorithm that detects along track surface water height and light penetration under a range of atmospheric and water conditions. The current analysis examines the data sets of three MABEL transects observed from 20 kilometers above ground of coastal and inland waters conducted in 2012 and 2013. Transects ranged from about 2 to 12 kilometers in length and included the middle Chesapeake Bay, the near-shore Atlantic coast at Virginia Beach, and Lake Mead. Results indicate MABEL's high capability for retrieving surface water height statistics with a mean height precision ofapproximately 5-7 centimeters per 100-meter segment length. Profiles of attenuated subsurface backscatter, characterized using a Signal to Background Ratio written in Log10 base, or LSBR (sub 0), were observed over a range of 1.3 to 9.3 meters, depending on water clarity and atmospheric background. Results indicate that observable penetration depth, although primarily dependent on water properties, was greatest when the solar background rate was low. Near-shore bottom reflectance was detected only at the Lake Mead site down to a maximum of 10 meters under a clear night sky and low turbidity of approximately 1

  15. The Ice Cap Zone: A Unique Habitable Zone for Ocean Worlds

    Science.gov (United States)

    Ramirez, Ramses M.; Levi, Amit

    2018-03-01

    Traditional definitions of the habitable zone assume that habitable planets contain a carbonate-silicate cycle that regulates CO2 between the atmosphere, surface, and the interior. Such theories have been used to cast doubt on the habitability of ocean worlds. However, Levi et al (2017) have recently proposed a mechanism by which CO2 is mobilized between the atmosphere and the interior of an ocean world. At high enough CO2 pressures, sea ice can become enriched in CO2 clathrates and sink after a threshold density is achieved. The presence of subpolar sea ice is of great importance for habitability in ocean worlds. It may moderate the climate and is fundamental in current theories of life formation in diluted environments. Here, we model the Levi et al. mechanism and use latitudinally-dependent non-grey energy balance and single-column radiative-convective models and find that this mechanism may be sustained on ocean worlds that rotate at least 3 times faster than the Earth. We calculate the circumstellar region in which this cycle may operate for G-M-stars (Teff = 2,600-5,800 K), extending from ˜1.23 - 1.65, 0.69 - 0.873, 0.38-0.528 AU, 0.219-0.308 AU, 0.146-0.206 AU, and 0.0428-0.0617 AU for G2, K3, M0, M3, M5, and M8 stars, respectively. However, unless planets are very young and not tidally-locked, our mechanism would be unlikely to apply to stars cooler than a ˜M3. We predict C/O ratios for our atmospheres (˜0.5) that can be verified by the JWST mission.

  16. Accuracy of Handheld Blood Glucose Meters at High Altitude

    NARCIS (Netherlands)

    de Mol, Pieter; Krabbe, Hans G.; de Vries, Suzanna T.; Fokkert, Marion J.; Dikkeschei, Bert D.; Rienks, Rienk; Bilo, Karin M.; Bilo, Henk J. G.

    2010-01-01

    Background: Due to increasing numbers of people with diabetes taking part in extreme sports (e. g., high-altitude trekking), reliable handheld blood glucose meters (BGMs) are necessary. Accurate blood glucose measurement under extreme conditions is paramount for safe recreation at altitude. Prior

  17. Climate Change Impacts on High-Altitude Ecosystems

    Directory of Open Access Journals (Sweden)

    Harald Pauli

    2016-02-01

    Full Text Available Reviewed: Climate Change Impacts on High-Altitude Ecosystems By Münir Öztürk, Khalid Rehman Hakeem, I. Faridah-Hanum and Efe. Recep, Cham, Switzerland: Springer International Publishing, 2015. xvii + 696 pp. US$ 239.00. ISBN 978-3-319-12858-0.

  18. Climate Change Impacts on High-Altitude Ecosystems

    OpenAIRE

    Harald Pauli

    2016-01-01

    Reviewed: Climate Change Impacts on High-Altitude Ecosystems By Münir Öztürk, Khalid Rehman Hakeem, I. Faridah-Hanum and Efe. Recep, Cham, Switzerland: Springer International Publishing, 2015. xvii + 696 pp. US$ 239.00. ISBN 978-3-319-12858-0.

  19. Civilian Training in High-Altitude Flight Physiology

    Science.gov (United States)

    1991-08-01

    A survey was conducted to determine if training in high-altitude physiology should : be required for civilian pilots; what the current status of such training was; and, : if required, what should be included in an ideal curriculum. The survey include...

  20. Limnology and cyanobacterial diversity of high altitude lakes of ...

    Indian Academy of Sciences (India)

    Limnological data of four high altitude lakes from the cold desert region of Himachal Pradesh, India, has been correlated with cyanobacterial diversity. Physico-chemical characteristics and nutrient contents of the studied lakes revealed that Sissu Lake is mesotrophic while Chandra Tal, Suraj Tal and Deepak Tal are ...

  1. Lens autofluorescence is not increased at high altitude

    DEFF Research Database (Denmark)

    Kessel, Line; Kofoed, Peter Kristian; Zubieta-Calleja, Gustavo

    2010-01-01

    in Denmark. RESULTS: No significant differences in lens fluorescence or transmittance were found between Bolivian and Danish volunteers. CONCLUSION: Age-corrected lens fluorescence and transmittance were comparable for healthy participants living at high altitude near the equator and healthy volunteers...

  2. Cold induced peripheral vasodilation at high altitudes- a field study

    NARCIS (Netherlands)

    Daanen, H.A.M.; Ruiten, H.J.A. van

    2000-01-01

    A significant reduction in cold-induced vasodilation (CIVD) is observed at high altitudes. No agreement is found in the literature about acclimatization effects on CIVD. Two studies were performed to investigate the effect of altitude acclimatization on CIVD. In the first study 13 male subjects

  3. Pathophysiology of acute mountain sickness and high altitude pulmonary oedema

    DEFF Research Database (Denmark)

    Sutton, J R; Lassen, N

    1979-01-01

    We review the evidence that acute mountain sickness (AMS) and high altitude pulmonary oedema (HAPO) occur together more often than is realized. We hypothesize that AMS and HAPO have a common pathophysiological basis: both are due to increased pressure and flow in the microcirculation, causing...

  4. Flight Control of the High Altitude Wind Power System

    NARCIS (Netherlands)

    Podgaets, A.R.; Ockels, W.J.

    2007-01-01

    Closed loop Laddermill flight control problem is considered in this paper. Laddermill is a high altitude kites system for energy production. The kites have been simulated as rigid bodies and the cable as a thin elastic line. Euler angles and cable speed are controls. Flight control is written as a

  5. Mast cells in the human lung at high altitude

    Science.gov (United States)

    Heath, Donald

    1992-12-01

    Mast cell densities in the lung were measured in five native highlanders of La Paz (3600 m) and in one lowlander dying from high-altitude pulmonary oedema (HAPO) at 3440 m. Two of the highlanders were mestizos with normal pulmonary arteries and the others were Aymara Indians with muscular remodelling of their pulmonary vasculature. The aim of the investigation was to determine if accumulation of mast cells in the lung at high altitude (HA) is related to alveolar hypoxia alone, to a combination of hypoxia and muscularization of the pulmonary arterial tree, or to oedema of the lung. The lungs of four lowlanders were used as normoxic controls. The results showed that the mast cell density of the two Mestizos was in the normal range of lowlanders (0.6-8.8 cells/mm2). In the Aymara Indians the mast cell counts were raised (25.6-26.0 cells/mm2). In the lowlander dying from HAPO the mast cell count was greatly raised to 70.1 cells/mm2 lung tissue. The results show that in native highlanders an accumulation of mast cells in the lung is not related to hypoxia alone but to a combination of hypoxia and muscular remodelling of the pulmonary arteries. However, the most potent cause of increased mast cell density in the lung at high altitude appears to be high-altitude pulmonary oedema.

  6. A new DEM of the Austfonna ice cap by combining differential SAR interferometry with ICESat laser altimetry

    Directory of Open Access Journals (Sweden)

    Geir Moholdt

    2012-05-01

    Full Text Available We present a new digital elevation model (DEM of the Austfonna ice cap in the Svalbard Archipelago, Norwegian Arctic. Previous DEMs derived from synthetic aperture radar (SAR and optical shape-from-shading have been tied to airborne radio echo-sounding surface profiles from 1983 which contain an elevation-dependent bias of up to several tens of metres compared with recent elevation data. The new and freely available DEM is constructed purely from spaceborne remote sensing data using differential SAR interferometry (DInSAR in combination with ICESat laser altimetry. Interferograms were generated from pairs of SAR scenes from the one-day repeat tandem phase of the European Remote Sensing Satellites 1/2 (ERS-1/2 in 1996. ICESat elevations from winter 2006–08 were used as ground control points to refine the interferometric baseline. The resulting DEM is validated against the same ground control points and independent surface elevation profiles from Global Navigation Satellite Systems (GNSS and airborne laser altimetry, yielding root mean square (RMS errors of about 10 m in all cases. This quality is sufficient for most glaciological applications, and the new DEM will be a baseline data set for ongoing and future research at Austfonna. The technique of combining satellite DInSAR with high-resolution satellite altimetry for DEM generation might also be a good solution in other glacier regions with similar characteristics, especially when data from TanDEM-X and CryoSat-2 become available.

  7. Why Are High Altitude Natives So Strong at High Altitude? Nature vs. Nurture: Genetic Factors vs. Growth and Development.

    Science.gov (United States)

    Brutsaert, Tom

    Among high-altitude natives there is evidence of a general hypoxia tolerance leading to enhanced performance and/or increased capacity in several important domains. These domains likely include an enhanced physical work capacity, an enhanced reproductive capacity, and an ability to resist several common pathologies of chronic high-altitude exposure. The "strength" of the high-altitude native in this regard may have both a developmental and a genetic basis, although there is better evidence for the former (developmental effects) than for the latter. For example, early-life hypoxia exposure clearly results in lung growth and remodeling leading to an increased O2 diffusing capacity in adulthood. Genetic research has yet to reveal a population genetic basis for enhanced capacity in high-altitude natives, but several traits are clearly under genetic control in Andean and Tibetan populations e.g., resting and exercise arterial O2 saturation (SaO2). This chapter reviews the effects of nature and nurture on traits that are relevant to the process of gas exchange, including pulmonary volumes and diffusion capacity, the maximal oxygen consumption (VO2max), the SaO2, and the alveolar-arterial oxygen partial pressure difference (A-aDO2) during exercise.

  8. The structure of high altitude O+ energization and outflow: a case study

    Directory of Open Access Journals (Sweden)

    H. Nilsson

    2004-07-01

    Full Text Available Multi-spacecraft observations from the CIS ion spectrometers on board the Cluster spacecraft have been used to study the structure of high-altitude oxygen ion energization and outflow. A case study taken from 12 April 2004 is discussed in more detail. In this case the spacecraft crossed the polar cap, mantle and high-altitude cusp region at altitudes between 4RE and 8RE and 2 of the spacecraft provided data. The oxygen ions were seen as a beam with narrow energy distribution, and increasing field-aligned velocity and temperature at higher altitude further in the upstream flow direction. The peak O+ energy was typically just above the highest energy of observed protons. The observed energies reached the upper limit of the CIS ion spectrometer, i.e. 38keV. Moment data from the spacecraft have been cross-correlated to determine cross-correlation coefficients, as well as the phase delay between the spacecraft. Structures in ion density, temperature and field-aligned flow appear to drift with the observed field-perpendicular drift. This, together with a velocity dispersion analysis, indicates that much of the structure can be explained by transverse heating well below the spacecraft. However, temperature isotropy and the particle flux as a function of field-aligned velocity are inconsistent with a single altitude Maxwellian source. Heating over extended altitude intervals, possibly all the way up to the observation point, seem consistent with the observations.

  9. Coca: High Altitude Remedy of the Ancient Incas.

    Science.gov (United States)

    Biondich, Amy Sue; Joslin, Jeremy D

    2015-12-01

    The use of coca leaf for medicinal purposes is a centuries-old tradition of the native peoples of South America. Coca products are thought by many laypersons to provide risk-free benefits to users participating in strenuous activities at high altitude. Physiologic studies of coca have increased understanding of its possible mechanism of action as well as its potential impact on high altitude activities. This present work explores the role of coca throughout the history of the Andean peoples and explores whether this ancient remedy has a place in modern medicine. A focused summary of research articles with particular relevance to the field of wilderness medicine is also included to better provide the reader with lessons not only from history but also from another culture. Copyright © 2015 Wilderness Medical Society. Published by Elsevier Inc. All rights reserved.

  10. Reduced oxygen at high altitude limits maximum size.

    Science.gov (United States)

    Peck, L S; Chapelle, G

    2003-11-07

    The trend towards large size in marine animals with latitude, and the existence of giant marine species in polar regions have long been recognized, but remained enigmatic until a recent study showed it to be an effect of increased oxygen availability in sea water of a low temperature. The effect was apparent in data from 12 sites worldwide because of variations in water oxygen content controlled by differences in temperature and salinity. Another major physical factor affecting oxygen content in aquatic environments is reduced pressure at high altitude. Suitable data from high-altitude sites are very scarce. However, an exceptionally rich crustacean collection, which remains largely undescribed, was obtained by the British 1937 expedition from Lake Titicaca on the border between Peru and Bolivia in the Andes at an altitude of 3809 m. We show that in Lake Titicaca the maximum length of amphipods is 2-4 times smaller than other low-salinity sites (Caspian Sea and Lake Baikal).

  11. Measurements of radioactive dust in high altitude air

    International Nuclear Information System (INIS)

    Kobayashi, Mika; Kohara, Eri; Muronoi, Naohiro; Masuda, Yousuke; Midou, Tomotaka; Ishida, Yukiko; Shimizu, Toshihiko; Saga, Minoru; Endo, Hiromu

    2012-01-01

    The radioactivity in samples of airborne dust was measured. The samples had been collected at high altitude by the Japan Air Self-Defense Force. The data were obtained for the gross beta activity, gamma nuclide determination and radiochemical analysis. It was shown that there was no appreciable difference between the activity levels obtained in this time and in the year before. Seasonal variations were not very pronounced. It was found that the radioactivity at high altitude had been stable at a low level. Radioactive gases (gaseous radioiodine and xenon gas) were not detected. This report does not include the result on radionuclide measurements that Technical Research and Development Institute executed for examining the nuclear emergency situation at Fukushima Daiichi and Daini nuclear power plants after Tohoku Region Pacific Ocean Earthquake on March 11, 2011. (author)

  12. The radiation protection problems of high altitude and space flight

    International Nuclear Information System (INIS)

    Fry, R.J.M.

    1993-01-01

    This paper considers the radiation environment in aircraft at high altitudes and spacecraft in low earth orbit and in deep space and the factors that influence the dose equivalents. Altitude, latitude and solar cycle are the major influences for flights below the radiation belts. In deep space, solar cycle and the occurrence of solar particle events are the factors of influence. The major radiation effects of concern are cancer and infertility in males. In high altitude aircraft the radiation consists mainly of protons and neutrons, with neutrons contributing about half the equivalent dose. The average dose rate at altitudes of transcontinental flights that approach the polar regions are greater by a factor of about 2.5 than on routes at low latitudes. Current estimates of does to air crews suggest they are well within the ICRP (1990) recommended dose limits for radiation workers

  13. Training-dependent cognitive advantage is suppressed at high altitude.

    Science.gov (United States)

    Li, Peng; Zhang, Gang; You, Hai-Yan; Zheng, Ran; Gao, Yu-Qi

    2012-06-25

    Ascent to high altitude is associated with decreases in cognitive function and work performance as a result of hypoxia. Some workers with special jobs typically undergo intensive mental training because they are expected to be agile, stable and error-free in their job performance. The purpose of this study was to determine the risk to cognitive function acquired from training following hypoxic exposure. The results of WHO neurobehavioral core tests battery (WHO-NCTB) and Raven's standard progressive matrices (RSPM) tests of a group of 54 highly trained military operators were compared with those of 51 non-trained ordinary people and were investigated at sea level and on the fifth day after arrival at high altitudes (3900m). Meanwhile, the plasma levels of brain-derived neurotrophic factor (BDNF), interleukin 1β (IL-1β) and vascular endothelial growth factor (VEGF) were examined. The result showed that at sea level, the trained group exhibited significantly better performance on neurobehavioral and RSPM tests. At high altitude, both groups had decreased accuracy in most cognitive tests and took longer to finish them. More importantly, the highly trained subjects showed more substantial declines than the non-trained subjects in visual reaction accuracy, auditory reaction speed, digit symbol scores, ability to report correct dots in a pursuit aiming test and total RSPM scores. This means that the training-dependent cognitive advantages in these areas were suppressed at high altitudes. The above phenomenon maybe associated with decreased BDNF and elevated inflammatory factor during hypoxia, and other mechanisms could not be excluded. Copyright © 2012 Elsevier Inc. All rights reserved.

  14. Wilderness medicine at high altitude: recent developments in the field

    OpenAIRE

    Shah, Neeraj M; Hussain, Sidra; Cooke, Mark; O’Hara, John P; Mellor, Adrian

    2015-01-01

    Neeraj M Shah,1 Sidra Hussain,2 Mark Cooke,3 John P O’Hara,3 Adrian Mellor3,4 1Division of Asthma, Allergy and Lung Biology, King’s College London, UK; 2School of Medicine, University College London, London, UK; 3Research Institute for Sport, Physical Activity and Leisure, Leeds Beckett University, Leeds, UK; 4Academic Department of Military Anaesthesia and Critical Care, Royal Centre for Defence Medicine, Birmingham, UK Abstract: Travel to high altitude is increasingly p...

  15. Nike Black Brant V high altitude dynamic instability characteristics

    Science.gov (United States)

    Montag, W. H.; Walker, L. L., Jr.

    1979-01-01

    Flight experience on the Nike Black Brant V has demonstrated the existence of plume induced flow separation over the fins and aft body of the Black Brant V motor. Modelling of the forces associated with this phenomenon as well as analysis of the resultant vehicle coning motion and its effect on the velocity vector heading are presented. A summary of Nike Black Brant V flight experience with high altitude dynamic instability is included.

  16. Increased Cardiometabolic Risk and Worsening Hypoxemia at High Altitude

    OpenAIRE

    Miele, Catherine H.; Schwartz, Alan R.; Gilman, Robert H.; Pham, Luu; Wise, Robert A.; Davila-Roman, Victor G.; Jun, Jonathan C.; Polotsky, Vsevolod Y.; Miranda, J. Jaime; Leon-Velarde, Fabiola; Checkley, William

    2016-01-01

    Miele, Catherine H., Alan R. Schwartz, Robert H. Gilman, Luu Pham, Robert A. Wise, Victor G. Davila-Roman, Jonathan C. Jun, Vsevolod Y. Polotsky, J. Jaime Miranda, Fabiola Leon-Velarde, and William Checkley. Increased cardiometabolic risk and worsening hypoxemia at high altitude. High Alt Med Biol. 17:93���100, 2016.���Metabolic syndrome, insulin resistance, diabetes, and dyslipidemia are associated with an increased risk of cardiovascular disease. While excessive erythrocytosis is associated...

  17. The yak genome and adaptation to life at high altitude

    DEFF Research Database (Denmark)

    Qiu, Qiang; Zhang, Guojie; Ma, Tao

    2012-01-01

    . Here, we present the draft genome sequence of a female domestic yak generated using Illumina-based technology at 65-fold coverage. Genomic comparisons between yak and cattle identify an expansion in yak of gene families related to sensory perception and energy metabolism, as well as an enrichment...... important implications for understanding adaptation to high altitude in other animal species and for hypoxia-related diseases in humans....

  18. High-Altitude Platforms — Present Situation and Technology Trends

    OpenAIRE

    d’Oliveira, Flavio Araripe; Melo, Francisco Cristovão Lourenço de; Devezas, Tessaleno Campos

    2016-01-01

    ABSTRACT High-altitude platforms (HAPs) are aircraft, usually unmanned airships or airplanes positioned above 20 km, in the stratosphere, in order to compose a telecommunications network or perform remote sensing. In the 1990 and 2000 decades, several projects were launched, but very few had continued. In 2014, 2 major Internet companies (Google and Facebook) announced investments in new HAP projects to provide Internet access in regions without communication infrastructure (terrestrial or sa...

  19. Differentiation of pulmonary embolism from high altitude pulmonary edema

    International Nuclear Information System (INIS)

    Khan, D.A.; Hashim, R.; Mirza, T.M.; Matloob-ur-Rehman, M.

    2003-01-01

    Objective: To differentiate the high altitude pulmonary edema (HAPE) from pulmonary embolism (PE) by clinical probability model of PE, lactate dehydrogenase (LDH), aspartate transaminase (AST) and D-dimer assays at high altitude. Subjects and Methods: Consecutive 40 patients evacuated from height > 3000 meters with symptoms of PE or HAPE were included. Clinical pretest probabilities scores of PE, Minutex D-dimer assay (Biopool international) and cardiac enzymes estimation by IFCC approved methods, were used for diagnosis. Mann-Whitney U test was applied by using SPSS and level of significance was taken at (p 500 ng/ml. Plasma D-dimer of 500 ng/ml was considered as cut-off value; 6(66.7%) patients of PE could be diagnosed and 30 (96.7%) cases of HAPE excluded indicating very good negative predictive value. Serum LDH, AST and CK were raised above the reference ranges in 8 (89%), 7 (78%) and 3 (33%) patients of PE as compared to 11 (35%), 6 (19%) and 9 (29%) of HAPE respectively. Conclusion: Clinical assessment in combination with D-dimer assay, LDH and AST can be used for timely differentiation of PE from HAPE at high altitude where diagnostic imaging procedures are not available. (author)

  20. S-40: Acute Phase Protein Increse in High Altitude Mountaineers

    Directory of Open Access Journals (Sweden)

    Tolga Saka

    2017-03-01

    Full Text Available “Erciyes Tigers” are an elite group of high altitude climbers. They have been climbing ErciyesMountain (3500 m, in Kayseri, Turkey once a week at least for ten years. When they climb Erciyes in winter, they also take a snow bath. This study investigated the effects of regular high altitude climbing on the metabolic and hematological responses of mountaineers. Venous blood samples were taken to investigate hematological, biochemical parameters and some hormone values from 21 mountaineers and 16 healthy age-matched sedentary volunteers at resting condition. The neutrophil/lymphocyte (N/L ratio was calculated. The N/L was associated with an increased risk of long-term mortality and it could provide a good measure of exercise stress and subsequent recovery. Most of the hematological and biochemical parameters i.e., erythrocyte, leukocyte, hemoglobin and hematocrit values did not change significantly. The neutrophil to lymphocyte (N/L ratio was significantly (p<0.04 decreased in the mountaineer compared with the sedentary group. Total protein (p<0.000 and albumin (0.001 were lower, while ferritin (p<0.04, creatine (p<0.03 and creatine phosphokinase levels (p<0.01 were higher in mountaineers. Our results show that regular high altitude climbing increased serum levels of some acute-phase proteins and these increments were not transient.

  1. Glacial Boundary Features Delineated Using Enhanced-resolution Passive-microwave Data to Determine Melt Season Variation of the Vatnajokull Ice Cap, Iceland

    Science.gov (United States)

    Marzillier, D. M.; Ramage, J. M.

    2017-12-01

    Temperate glaciers such as those seen in Iceland experience high annual mass flux, thereby responding to small scale changes in Earth's climate. Decadal changes in the glacial margins of Iceland's ice caps are observable in the Landsat record, however twice daily AMSR-E Calibrated Enhanced-Resolution Passive Microwave Daily EASE-Grid 2.0 Brightness Temperature (CETB) Earth System Data Record (ESDR) allow for observation on a daily temporal scale and a 3.125 km spatial scale, which can in turn be connected to patterns seen over longer periods of time. Passive microwave data allow for careful observation of melt onset and duration in Iceland's glacial regions by recording changes in emissivity of the ice surface, known as brightness temperature (TB), which is sensitive to fluctuations in the liquid water content of snow and ice seen during melting in glaciated regions. Enhanced resolution of this data set allows for a determination of a threshold that defines the melting season. The XPGR snowmelt algorithm originally presented by Abdalati and Steffen (1995) is used as a comparison with the diurnal amplitude variation (DAV) values on Iceland's Vatnajokull ice cap located at 64.4N, -16.8W. Ground-based air temperature data in this region, digital elevation models (DEMs), and river discharge dominated by glacial runoff are used to confirm the glacial response to changes in global climate. Results show that Iceland glaciers have a bimodal distribution of brightness temperature delineating when the snow/ice is melting and refreezing. Ground based temperatures have increased on a decadal trend. Clear glacial boundaries are visible on the passive microwave delineating strong features, and we are working to understand their variability and contribution to glacier evolution. The passive microwave data set allows connections to be made between observations seen on a daily scale and the long term glacier changes observed by the Landsat satellite record that integrates the

  2. Basal friction evolution and crevasse distribution during the surge of Basin 3, Austfonna ice-cap - offline coupling between a continuum ice dynamic model and a discrete element model

    Science.gov (United States)

    Gong, Yongmei; Zwinger, Thomas; Åström, Jan; Gladstone, Rupert; Schellenberger, Thomas; Altena, Bas; Moore, John

    2017-04-01

    The outlet glacier at Basin 3, Austfonna ice-cap entered its active surge phase in autumn 2012. We assess the evolution of the basal friction during the surge through inverse modelling of basal friction coefficients using recent velocity observation from 2012 to 2014 in a continuum ice dynamic model Elmer/ice. The obtained basal friction coefficient distributions at different time instances are further used as a boundary condition in a discrete element model (HiDEM) that is capable of computing fracturing of ice. The inverted basal friction coefficient evolution shows a gradual 'unplugging' of the stagnant frontal area and northwards and inland expansion of the fast flowing region in the southern basin. The validation between the modeled crevasses distribution and the satellite observation in August 2013 shows a good agreement in shear zones inland and at the frontal area. Crevasse distributions of the summer before and after the glacier reached its maximum velocity in January 2013 (August 2012 and August 2014, respectively) are also evaluated. Previous studies suggest the triggering and development of the surge are linked to surface melt water penetrating through ice to form an efficient basal hydrology system thereby triggering a hydro- thermodynamic feedback. This preliminary offline coupling between a continuum ice dynamic model and a discrete element model will give a hint on future model development of linking supra-glacial to sub-glacial hydrology system.

  3. High Altitude Venus Operations Concept Trajectory Design, Modeling and Simulation

    Science.gov (United States)

    Lugo, Rafael A.; Ozoroski, Thomas A.; Van Norman, John W.; Arney, Dale C.; Dec, John A.; Jones, Christopher A.; Zumwalt, Carlie H.

    2015-01-01

    A trajectory design and analysis that describes aerocapture, entry, descent, and inflation of manned and unmanned High Altitude Venus Operation Concept (HAVOC) lighter-than-air missions is presented. Mission motivation, concept of operations, and notional entry vehicle designs are presented. The initial trajectory design space is analyzed and discussed before investigating specific trajectories that are deemed representative of a feasible Venus mission. Under the project assumptions, while the high-mass crewed mission will require further research into aerodynamic decelerator technology, it was determined that the unmanned robotic mission is feasible using current technology.

  4. Navigation and Positioning System Using High Altitude Platforms Systems (HAPS)

    Science.gov (United States)

    Tsujii, Toshiaki; Harigae, Masatoshi; Harada, Masashi

    Recently, some countries have begun conducting feasibility studies and R&D projects on High Altitude Platform Systems (HAPS). Japan has been investigating the use of an airship system that will function as a stratospheric platform for applications such as environmental monitoring, communications and broadcasting. If pseudolites were mounted on the airships, their GPS-like signals would be stable augmentations that would improve the accuracy, availability, and integrity of GPS-based positioning systems. Also, the sufficient number of HAPS can function as a positioning system independent of GPS. In this paper, a system design of the HAPS-based positioning system and its positioning error analyses are described.

  5. WCDMA Uplink Interference Assessment from Multiple High Altitude Platform Configurations

    Directory of Open Access Journals (Sweden)

    A. Mohammed

    2008-06-01

    Full Text Available We investigate the possibility of multiple high altitude platform (HAP coverage of a common cell area using a wideband code division multiple access (WCDMA system. In particular, we study the uplink system performance of the system. The results show that depending on the traffic demand and the type of service used, there is a possibility of deploying 3–6 HAPs covering the same cell area. The results also show the effect of cell radius on performance and the position of the multiple HAP base stations which give the worst performance.

  6. Performance simulation in high altitude platforms (HAPs) communications systems

    Science.gov (United States)

    Ulloa-Vásquez, Fernando; Delgado-Penin, J. A.

    2002-07-01

    This paper considers the analysis by simulation of a digital narrowband communication system for an scenario which consists of a High-Altitude aeronautical Platform (HAP) and fixed/mobile terrestrial transceivers. The aeronautical channel is modelled considering geometrical (angle of elevation vs. horizontal distance of the terrestrial reflectors) and statistical arguments and under these circumstances a serial concatenated coded digital transmission is analysed for several hypothesis related to radio-electric coverage areas. The results indicate a good feasibility for the communication system proposed and analysed.

  7. WCDMA Uplink Interference Assessment from Multiple High Altitude Platform Configurations

    Directory of Open Access Journals (Sweden)

    Grace D

    2008-01-01

    Full Text Available Abstract We investigate the possibility of multiple high altitude platform (HAP coverage of a common cell area using a wideband code division multiple access (WCDMA system. In particular, we study the uplink system performance of the system. The results show that depending on the traffic demand and the type of service used, there is a possibility of deploying 3–6 HAPs covering the same cell area. The results also show the effect of cell radius on performance and the position of the multiple HAP base stations which give the worst performance.

  8. Snow chemistry of high altitude glaciers in the French Alps

    OpenAIRE

    MAUPETIT, FRANÇOIS; DELMAS, ROBERT J.

    2011-01-01

    Snow samples were collected as snowcores in the accumulation zone of four high altitude glaciers (2980–3540 m.a.s.l.) from each of the 4 highest mountain areas of the French Alps, during 3 consecutive years: 1989, 1990 and 1991. Sampling was performed in spring (∼ May), before the onset of late spring–summer percolation. The accumulated snow therefore reflects winter and spring conditions. A complementary sampling of fresh-snow was performed on an event basis, on one of the studied glaciers, ...

  9. Electromagnetic coupling of high-altitude, nuclear electromagnetic pulses

    International Nuclear Information System (INIS)

    Anon.

    1984-01-01

    We have used scale models to measure the predicted coupling of electromagnetic fields simulating the effects of high-altitude nuclear electromagnetic pulses (HEMP) on the interior surfaces of electronic components. Predictive tools for exterior coupling are adequate. For interior coupling, however, such tools are in their infancy. Our methodological approach combines analytical, computational, and laboratory techniques in a complementary way to take advantage of their separate strengths. Computer models are a promising tool, as they can be used to treat complex objects with arbitrary shapes, dielectrics, and cables, and multiple apertures. Laboratory tests can expand the domain of investigation even further

  10. The GRAD high-altitude balloon flight over Antarctica

    International Nuclear Information System (INIS)

    Eichhorn, G.; Coldwell, R.L.; Dunnam, F.E.; Rester, A.C.; Trombka, J.I.; Starr, R.; Lasche, G.P.

    1989-01-01

    The Gamma Ray Advanced Detector(GRAD) consists of a n-type germanium detector inside an active bismuth-germanate Compton and charged particle shield with additional active plastic shielding across the aperture. It will be flown on a high altitude balloon at 36 km altitude at a latitude of 78 degree S over Antarctica for observations of gamma radiation emitted by the radioactive decay of 56 Co in the Supernova SN1987A, for assessment of the performance of bismuth-germanate scintillation material in the radiation environment of near space, for gathering information on the gamma-ray background over Antarctica, and for testing fault-tolerant software

  11. High-altitude electromagnetic pulse environment over the lossy ground

    International Nuclear Information System (INIS)

    Xie Yanzhao; Wang Zanji

    2003-01-01

    The electromagnetic field above ground produced by an incident high-altitude electromagnetic pulse plane wave striking the ground plane was described in this paper in terms of the Fresnel reflection coefficients and the numerical FFT. The pulse reflected from the ground plane always cancel the incident field for the horizontal field component, but the reflected field adds to the incident for the vertical field component. The results of several cases for variations in the observation height, angle of incidence and lossy ground electrical parameters were also presented showing different e-field components above the earth

  12. Increased Cardiometabolic Risk and Worsening Hypoxemia at High Altitude.

    Science.gov (United States)

    Miele, Catherine H; Schwartz, Alan R; Gilman, Robert H; Pham, Luu; Wise, Robert A; Davila-Roman, Victor G; Jun, Jonathan C; Polotsky, Vsevolod Y; Miranda, J Jaime; Leon-Velarde, Fabiola; Checkley, William

    2016-06-01

    Miele, Catherine H., Alan R. Schwartz, Robert H. Gilman, Luu Pham, Robert A. Wise, Victor G. Davila-Roman, Jonathan C. Jun, Vsevolod Y. Polotsky, J. Jaime Miranda, Fabiola Leon-Velarde, and William Checkley. Increased cardiometabolic risk and worsening hypoxemia at high altitude. High Alt Med Biol. 17:93-100, 2016.-Metabolic syndrome, insulin resistance, diabetes, and dyslipidemia are associated with an increased risk of cardiovascular disease. While excessive erythrocytosis is associated with cardiovascular complications, it is unclear how worsening hypoxemia of any degree affects cardiometabolic risk factors in high-altitude populations. We studied the relationship between daytime resting oxyhemoglobin saturation and cardiometabolic risk factors in adult participants living in Puno, Peru (3825 m above sea level). We used multivariable logistic regression models to study the relationship between having a lower oxyhemoglobin saturation and markers of cardiometabolic risk. Nine hundred and fifty-four participants (mean age 55 years, 52% male) had information available on pulse oximetry and markers of cardiometabolic risk. Average oxyhemoglobin saturation was 90% (interquartile range 88%-92%) and 43 (4.5%) had excessive erythrocytosis. Older age, decreased height-adjusted lung function, and higher body mass index (BMI) were associated with having an oxyhemoglobin saturation ≤85%. When adjusting for age, sex, socioeconomic status, having excessive erythrocytosis, and site, we found that each 5% decrease in oxyhemoglobin saturation was associated with a higher adjusted odds of metabolic syndrome (OR = 1.35, 95% CI: 1.07-1.72, p 2 mass units (OR = 1.29, 95% CI: 1.00-1.67, p < 0.05), hemoglobin A1c ≥6.5% (OR = 1.66, 95% CI: 1.09-2.51, p < 0.04), and high sensitivity C-reactive protein (hs-CRP) ≥3 mg/L (OR = 1.46, 95% CI: 1.09-1.96, p < 0.01). In high-altitude populations in Puno, Peru, a higher BMI and lower pulmonary function were

  13. Moessbauer studies of hemoglobin in high altitude polycythemia

    International Nuclear Information System (INIS)

    Zhang Xiufang; Shen Linming; Chen Songsen; Ao Zhaohui; Liu Yuanyuan; Gao Naifei; Zheng Yuanming; Shong Liangquan

    1990-01-01

    The Moessbauer spectra have been measured in erythrocytes from normal adults and the patients with high altitude polycythemia (HAPC). The results indicated that two subspectra ''a'' and ''b'', corresponding to oxy- and deoxyhemoglobin respectively, were present in all blood samples, and a third subspectrum ''c'' was found to exist in almost all samples from the patients. The parameters of the third subspectra ''c1'' in most samples from the patients were similar to those of carbon monoxyhemoglobin. The components were considered to be the denatured hemoglobin in RBCs (red blood cells). Together with clinical analysis, a possible mechanism of HAPC has been discussed. (orig.)

  14. Mössbauer studies of hemoglobin in high altitude polycythemia

    Science.gov (United States)

    Xiufang, Zhang; Linming, Shen; Songsen, Chen; Yuanyuan, Liu; Naifei, Gao; Yuanming, Zheng; Zhaohui, Ao; Liangquan, Shong

    1990-07-01

    The Mössbauer spectra have been measured in erythrocytes from normal adults and the patients with high altitude polycythemia (HAPC). The results indicated that two subspectra “a” and “b”, corresponding to oxy- and deoxyhemoglobin respectively, were present in all blood samples, and a third subspectrum “c” was found to exist in almost all samples from the patients. The parameters of the third subspectra “cl” in most samples from the patients were similar to those of carbon monoxyhemoglobin. The components were considered to be the denatured hemoglobin in RBCs (red blood cells). Together with clinical analysis, a possible mechanism of HAPC has been discussed.

  15. Diagnostic criteria of high-altitude de-adaptation for high-altitude migrants returning to the plains: a multicenter, randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Qi-quan ZHOU

    2012-02-01

    Full Text Available Objective  To investigate the diagnostic method of high-altitude de-adaptation and constitute the diagnostic criteria of high-altitude de-adaptation for people returning to the plains from high-altitude. Methods  Epidemiological survey and clinical multicenter randomized controlled studies were used to determine/perform blood picture, routine urine analysis, routine stool examination, myocardial enzymes, liver and kidney functions, nerve function, sex hormone, microalbuminuria, ECG, echocardiography, pulmonary function tests, and so on, in 3011 subjects after they returned to the plains from high-altitude. The diagnostic criteria of high-altitude de-adaptation were formulated by a comparative analysis of the obtained data with those of healthy subjects living in the same area, altitude, and age. The regularity and characteristics of high-altitude de-adaptation syndrome were found and diagnostic criteria for high-altitude de-adaptation was established based on the results. Results  The investigative results showed that the incidence of high-altitude de-adaptation syndrome was found in 84.36% of population returning to the plains from high-altitude. About 60% of them were considered to have mild reactions, 30% medium, and only 10% were severe. The lower the altitude they returned to, the longer the duration of stay in highland, and the heavier the labor they engaged in high altitude, the higher the incidence rate of high-altitude de-adaptation syndrome was. Patients with high-altitude de-adaptation syndrome exhibited hematological abnormality and abnormal ventricular function, especially the right ventricular diastolic function after returning for 1 year to 5 years. Long-term hypoxia exposure often caused obvious change in cardiac morphology with left and right ventricular hypertrophy, particularly the right ventricle. In addition, low blood pressure and low pulse pressure were found at times. Microalbuminuria was found in some high-altitude de

  16. A late Holocene metal record of Andean climate and anthropogenic activity in lake sediments near Quelccaya Ice Cap, Peru

    Science.gov (United States)

    Beal, S. A.; Kelly, M. A.; Jackson, B. P.; Stroup, J. S.; Osterberg, E. C.

    2011-12-01

    The tropical hypothesis maintains that major changes in global climate are motivated by phenomena based at tropical latitudes. Evidence for this hypothesis lies in: modern-day observations of El Niño Southern Oscillation (ENSO); East African lake sediment records of Intertropical Convergence Zone (ITCZ) position that precede high-latitude changes; and the potential for ITCZ shifts to cause major CO2 degassing from the Southern Ocean. In order to improve the understanding of these phenomena we present an ~1800 year record of atmospheric metal deposition in a lake sediment core near Quelccaya Ice Cap, Peru (13.9 °S). In June, 2010 we collected a 1.45 meter-long core from Yanacocha - a small, closed-basin tarn that has been isolated from glacial input since ~11,200 BP. The chronology for the core is based on 4 of 6 AMS 14C dates on aquatic macrofossils and one sharp Zr/Ti anomaly at 36 cm, likely derived from the 350 BP eruption of Huaynaputina. We completely digested organic-rich core samples at 1 cm resolution using HNO3, HCl, and HF in a closed-vessel microwave system, and then analyzed the digestates for 67 metals by inductively coupled plasma mass spectrometry. Here we show fluxes of lithogenic metals (Fe, Nb, Ti, and Zr) that reflect changes in wind strength and aridity, fluxes of lithogenic metal isotopes (REEs and Pb) that reflect wind direction, and enrichment factors (EFs) of metals (Ag, As, Cd, Cu, Hg, and Pb) that reflect anthropogenic activity. Five episodic peaks in lithogenic metal fluxes, centered around 1800, 1300, 900, 600, and 100 yrs BP, are thought to result from either drier or windier conditions, potentially caused by a northern ITCZ position or a more persistent El Niño state. The provenance of atmospheric deposition, evidenced by REE ratios (light REEs / heavy REEs), suggest that high lithogenic fluxes are associated with a change in wind direction, possibly caused by a change in the ENSO state, which will be explored with forthcoming Pb

  17. Key issues of ultraviolet radiation of OH at high altitudes

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Yuhuai; Wan, Tian; Jiang, Jianzheng; Fan, Jing [State Key Laboratory of High Temperature Gasdynamics, Institute of Mechanics, Chinese Academy of Sciences, Beijing 100190 (China)

    2014-12-09

    Ultraviolet (UV) emissions radiated by hydroxyl (OH) is one of the fundamental elements in the prediction of radiation signature of high-altitude and high-speed vehicle. In this work, the OH A{sup 2}Σ{sup +}→X{sup 2}Π ultraviolet emission band behind the bow shock is computed under the experimental condition of the second bow-shock ultraviolet flight (BSUV-2). Four related key issues are discussed, namely, the source of hydrogen element in the high-altitude atmosphere, the formation mechanism of OH species, efficient computational algorithm of trace species in rarefied flows, and accurate calculation of OH emission spectra. Firstly, by analyzing the typical atmospheric model, the vertical distributions of the number densities of different species containing hydrogen element are given. According to the different dominating species containing hydrogen element, the atmosphere is divided into three zones, and the formation mechanism of OH species is analyzed in the different zones. The direct simulation Monte Carlo (DSMC) method and the Navier-Stokes equations are employed to compute the number densities of the different OH electronically and vibrationally excited states. Different to the previous work, the trace species separation (TSS) algorithm is applied twice in order to accurately calculate the densities of OH species and its excited states. Using a non-equilibrium radiation model, the OH ultraviolet emission spectra and intensity at different altitudes are computed, and good agreement is obtained with the flight measured data.

  18. Effect of phosphate supplementation on oxygen delivery at high altitude

    Science.gov (United States)

    Jain, S. C.; Singh, M. V.; Rawal, S. B.; Sharma, V. M.; Divekar, H. M.; Tyagi, A. K.; Panwar, M. R.; Swamy, Y. V.

    1987-09-01

    In the present communication, effect of low doses of phosphate supplementation on short-term high altitude adaptation has been examined. Studies were carried out in 36 healthy, male, sea-level residents divided in a double blind fashion into drug and placebo treated groups. 3.2 mmol of phosphate were given orally to each subject of the drug treated group once a day for 4 days on arrival at an altitude of 3,500 m. Sequential studies were done in the subjects in both groups on the 3rd, 7th, 14th and 21st day of their altitude stay. Haemoglobin, haematocrit, erythrocyte and reticulocyte counts increased to the similar extent in both groups. Blood pH, pO2 and adenosine tri-phosphate (ATP) did not differ between the two groups. On 3rd day of the altitude stay, inorganic phosphate and 2,3-diphosphoglycerate (2,3 DPG) levels in the drug treated group increased significantly as compared to the placebo group. No significant difference in inorganic phosphate and 2,3 DPG was observed later on in the two groups. Psychological and clinical tests also indicated that the drug treated subjects felt better as compared to the placebo treated subjects. The present study suggests that low doses of phosphate increases circulating 2,3-DPG concentration which in turn brings about beneficial effect towards short term high altitude adaptation.

  19. ACUTE PHASE PROTEIN INCREASE IN HIGH ALTITUDE MOUNTAINEERS

    Directory of Open Access Journals (Sweden)

    Tolga Saka

    Full Text Available ABSTRACT Introduction: Many middle-aged Turks go hiking in mountains to breathe some fresh air or to maintain fitness. Objective: This study investigated the effects of regular high altitude mountain climbing on the metabolic and hematological responses of mountaineers. Methods: Hematological and biochemical parameters were studied, as well as some hormonal values of 21 mountaineers and 16 healthy age-matched sedentary volunteers. Results: The neutrophil to lymphocyte ratio (NLR was significantly lower (p<0.04 in mountaineers compared with the sedentary group. Total protein (p<0.001 and albumin (p<0.001 were lower, while the levels of ferritin (p<0.04, creatine (p<0.03 and creatine phosphokinase (p<0.01 were higher in mountaineers. Other hematological and biochemical parameters, i.e., erythrocytes, leukocytes, hemoglobin and hematocrit, did not change significantly. Conclusion: Our results show that regular exposure to high altitude increased the serum levels of some acute phase proteins with anti-inflammatory properties.

  20. Increased insulin requirements during exercise at very high altitude in type 1 diabetes

    NARCIS (Netherlands)

    de Mol, Pieter; de Vries, Suzanna T.; de Koning, Eelco J. P.; Gans, Rijk O. B.; Tack, Cees J.; Bilo, Henk J. G.

    OBJECTIVE-Safe, very high altitude trekking in subjects with type 1 diabetes requires understanding of glucose regulation at high altitude. We investigated insulin requirements, energy expenditure, and glucose levels at very high altitude in relation to acute mountain sickness (AMS) symptoms in

  1. Oxygen binding properties, capillary densities and heart weights in high altitude camelids.

    Science.gov (United States)

    Jürgens, K D; Pietschmann, M; Yamaguchi, K; Kleinschmidt, T

    1988-01-01

    The oxygen binding properties of the blood of the camelid species vicuna, llama, alpaca and dromedary camel were measured and evaluated with respect to interspecific differences. The highest blood oxygen affinity, not only among camelids but of all mammals investigated so far, was found in the vicuna (P50 = 17.6 Torr compared to 20.3-21.6 Torr in the other species). Low hematocrits (23-34%) and small red blood cells (21-30 microns 3) are common features of all camelids, but the lowest values are found in the Lama species. Capillary densities were determined in heart and soleus muscle of vicuna and llama. Again, the vicuna shows exceptional values (3720 cap/mm2 on average in the heart) for a mammal of this body size. Finally, heart weight as percent of body weight is higher in the vicuna (0.7-0.9%) than in the other camelids studied (0.5-0.7%). The possibility that these parameters, measured in New World tylopodes at sea level, are not likely to change considerably with transfer to high altitude, is discussed. In the vicuna, a unique combination of the following features seems to be responsible for an outstanding physical capability at high altitude: saturation of blood with oxygen in the lung is favored by a high blood oxygen affinity, oxygen supply being facilitated by low diffusion distances in the muscle tissue. Loading, as well as unloading, of oxygen is improved by a relatively high oxygen transfer conductance of the red blood cells, which is due to their small size and which compensates the negative effect of a low hematocrit on the oxygen conductance of blood.(ABSTRACT TRUNCATED AT 250 WORDS)

  2. Large high altitude air shower observatory (LHAASO) project

    International Nuclear Information System (INIS)

    He Huihai

    2010-01-01

    The Large High Altitude Air Shower Observatory (LHAASO) project focuses mainly on the study of 40 GeV-1 PeV gamma ray astronomy and 10 TeV-1 EeV cosmic ray physics. It consists of a 1 km 2 extensive air shower array with 40 000 m 2 muon detectors, 90,000m 2 water Cerenkov detector array, 5 000 m 2 shower core detector array and an air Cerenkov/fluorescence telescope array. Prototype detectors are designed with some of them already in operation. A prototype array of 1% size of LHAASO will be built at the Yangbajing Cosmic Ray Observatory and used to coincidently measure cosmic rays with the ARGO-YBJ experiment. (authors)

  3. High-altitude wind resources in the Middle East

    KAUST Repository

    Yip, Chak Man Andrew; Gunturu, Udaya; Stenchikov, Georgiy L.

    2017-01-01

    In the Middle East, near-surface wind resources are intermittent. However, high-altitude wind resources are abundant, persistent, and readily available and may provide alternative energy resources in this fossil-fuel-dependent region. Using wind field data from the Modern-Era Retrospective Analysis for Research and Applications Version 2 (MERRA-2), this study identifies areas favorable to the deployment of airborne wind energy (AWE) systems in the Middle East and computes the optimal heights at which such systems would best operate. AWE potential is estimated using realistic AWE system specifications and assumptions about deployment scenarios and is compared with the near-surface wind generation potential with respect to diurnal and seasonal variability. The results show the potential utility of AWE in areas in the Middle East where the energy demand is high. In particular, Oman and Saudi Arabia have a high level of the potential power generation with low annual variability.

  4. Anthropometric survey of high-altitude Bolivian porters.

    Science.gov (United States)

    Leatherman, T L; Thomas, R B; Greksa, L P; Haas, J D

    1984-01-01

    This paper presents the results of an anthropometric survey of 138 rural Aymaran high-altitude males who were working as porters in La Paz, Bolivia (3700 m). All subjects were measured for stature, weight, upper arm circumference, and triceps skinfolds. The body size and composition of the porters were then compared to an Aymaran rural population from the Bolivian highlands, and urban mestizo labourers from La Paz. The porters were smaller than the urban sample, but appeared to be generally representative of rural Aymaran natives with respect to body size and composition, and nutritional status. It is suggested that towards one extreme of nutritional variability, some degree of undernutrition may be indicated, which should be considered in future studies of adaptation to hypoxia among these Andean highlanders.

  5. Sequencing of 50 human exomes reveals adaptation to high altitude

    DEFF Research Database (Denmark)

    Yi, Xin; Liang, Yu; Huerta-Sanchez, Emilia

    2010-01-01

    Residents of the Tibetan Plateau show heritable adaptations to extreme altitude. We sequenced 50 exomes of ethnic Tibetans, encompassing coding sequences of 92% of human genes, with an average coverage of 18x per individual. Genes showing population-specific allele frequency changes, which repres...... in genetic adaptation to high altitude.......Residents of the Tibetan Plateau show heritable adaptations to extreme altitude. We sequenced 50 exomes of ethnic Tibetans, encompassing coding sequences of 92% of human genes, with an average coverage of 18x per individual. Genes showing population-specific allele frequency changes, which...... represent strong candidates for altitude adaptation, were identified. The strongest signal of natural selection came from endothelial Per-Arnt-Sim (PAS) domain protein 1 (EPAS1), a transcription factor involved in response to hypoxia. One single-nucleotide polymorphism (SNP) at EPAS1 shows a 78% frequency...

  6. High-altitude haematology: Quechua-Aymara comparisons.

    Science.gov (United States)

    Arnaud, J; Quilici, J C; Rivière, G

    1981-01-01

    Haematological studies have been carried out at various altitudes between 450 m and 4800 m, on two separate human groups (Quechuas and Aymaras) living in South America. Changes in the haematological parameters do not develop linearly in relation to the attitude. Th impact of chronic hypoxia on erythropoiesis is greater above 3000 m. The haemogram varies quantitatively and not qualitatively (mean corpuscular volume and mean haemoglobin concentration remain constant). The haematological study also reveals the greater adaptability to high altitude of the Aymaras, an adaptability characterized by an increase in red cell count and concentration and a decrease in red cell volume. The adaptative phenomena observed in the Quechuas are reversible, whereas they persist in the Aymaras when they migrate to the lowlands (450 m).

  7. High-altitude wind resources in the Middle East

    KAUST Repository

    Yip, Chak Man Andrew

    2017-08-23

    In the Middle East, near-surface wind resources are intermittent. However, high-altitude wind resources are abundant, persistent, and readily available and may provide alternative energy resources in this fossil-fuel-dependent region. Using wind field data from the Modern-Era Retrospective Analysis for Research and Applications Version 2 (MERRA-2), this study identifies areas favorable to the deployment of airborne wind energy (AWE) systems in the Middle East and computes the optimal heights at which such systems would best operate. AWE potential is estimated using realistic AWE system specifications and assumptions about deployment scenarios and is compared with the near-surface wind generation potential with respect to diurnal and seasonal variability. The results show the potential utility of AWE in areas in the Middle East where the energy demand is high. In particular, Oman and Saudi Arabia have a high level of the potential power generation with low annual variability.

  8. High-Altitude Platforms - Present Situation and Technology Trends

    Directory of Open Access Journals (Sweden)

    Flavio Araripe D'Oliveira

    2016-07-01

    Full Text Available High-altitude platforms (HAPs are aircraft, usually unmanned airships or airplanes positioned above 20 km, in the stratosphere, in order to compose a telecommunications network or perform remote sensing. In the 1990 and 2000 decades, several projects were launched, but very few had continued. In 2014, 2 major Internet companies (Google and Facebook announced investments in new HAP projects to provide Internet access in regions without communication infrastructure (terrestrial or satellite, bringing back attention to the development of HAP. This article aims to survey the history of HAPs, the current state-of-the-art (April 2016, technology trends and challenges. The main focus of this review will be on technologies directly related to the aerial platform, inserted in the aeronautical engineering field of knowledge, not detailing aspects of the telecommunications area.

  9. Serum creatine kinase elevations in ultramarathon runners at high altitude.

    Science.gov (United States)

    Magrini, Danielle; Khodaee, Morteza; San-Millán, Iñigo; Hew-Butler, Tamara; Provance, Aaron J

    2017-05-01

    Creatine kinase (CK) is a sensitive enzyme marker for muscle damage in athletes. Elevated CK levels have been reported in many endurance physical activities. The consequence and possible long-term sequela of the CK elevation in athletes is unknown. There is a paucity of literature stating actual numerical values of CK associated with competing in an ultramarathon with extreme environmental conditions. Our hypothesis was that the serum CK levels increase significantly as a result of running a 161 km ultramarathon at high altitude. This was a prospective observational study of participants of the Leadville 100 ultramarathon race in Leadville, Colorado at high altitude (2800-3840 m) in August 2014. We collected blood samples from sixty-four volunteer runners before and eighty-three runners immediately after the race. Out of 669 athletes who started the race, 352 successfully completed the race in less than the 30-hour cut-off time (52%). The majority of runners were male (84%). We were able to collect both pre- and post-race blood samples from 36 runners. Out of these 36 runners, the mean pre-race CK was increased from 126 ± 64 U/L to 14,569 ± 14,729 U/L (p athletes' age, BMI, or finishing time. Significant elevation of CK level occurs as a result of running ultramarathons. The majority of athletes with significantly elevated CK levels were asymptomatic and required no major medical attention.

  10. Oxidative stress at high altitude: genotype–phenotype correlations

    Directory of Open Access Journals (Sweden)

    Pandey P

    2014-05-01

    Full Text Available Priyanka Pandey,1,2 MA Qadar Pasha1,2 1CSIR-Institute of Genomics and Integrative Biology, Delhi, India; 2Department of Biotechnology, University of Pune, Ganeshkhind, Pune, India Abstract: It has been well-documented that the hypobaric hypoxic environment at high altitude (HA causes stress to both the permanent residents of HA and the sojourners. This oxidative stress primarily disturbs the oxygen-sensing and vascular homeostasis pathways, thereby upsetting normal human physiology, especially in sojourners. These environmental challenges have caused dynamic evolutionary changes within natives of HA, allowing them to develop adaptive plasticity. This review focuses on the genomic and biochemical features of the molecules involved in the oxygen-sensing and vascular homeostasis pathways with respect to HA pulmonary edema (HAPE and adaptation. We review the role of genetic markers such as HIF-prolyl hydroxylase 2, endothelial PAS domain-containing protein 1, endothelial nitric oxide synthase, endothelin 1, cytochrome b-245 alpha polypeptide, and glutathione S-transferase pi 1, as well as three circulatory biomarkers (nitric oxide, endothelin 1, and 8-iso-prostaglandin F2α, by highlighting approaches such as candidate gene and genome-wide, adopted in deciphering the pathways. A disagreement between the two approaches has also been highlighted. In addition, we discuss that an overrepresentation of wild-type alleles in HA natives and mutant alleles of same polymorphisms in HAPE patients implies that the allelic variants at the same locus are involved in adaptation and HAPE, respectively. Moreover, healthy sojourners present a number of genomic features similar to HA natives, further strengthening the concept of genetic predisposition. A trend in correlation between protective and risk alleles and altered levels of circulatory markers clearly documents the phenomenon of genotype–phenotype correlations. We conclude that the genetic and biochemical

  11. Wilderness medicine at high altitude: recent developments in the field

    Directory of Open Access Journals (Sweden)

    Shah NM

    2015-09-01

    Full Text Available Neeraj M Shah,1 Sidra Hussain,2 Mark Cooke,3 John P O’Hara,3 Adrian Mellor3,4 1Division of Asthma, Allergy and Lung Biology, King’s College London, UK; 2School of Medicine, University College London, London, UK; 3Research Institute for Sport, Physical Activity and Leisure, Leeds Beckett University, Leeds, UK; 4Academic Department of Military Anaesthesia and Critical Care, Royal Centre for Defence Medicine, Birmingham, UK Abstract: Travel to high altitude is increasingly popular. With this comes an increased incidence of high-altitude illness and therefore an increased need to improve our strategies to prevent and accurately diagnose these. In this review, we provide a summary of recent advances of relevance to practitioners who may be advising travelers to altitude. Although the Lake Louise Score is now widely used as a diagnostic tool for acute mountain sickness (AMS, increasing evidence questions the validity of doing so, and of considering AMS as a single condition. Biomarkers, such as brain natriuretic peptide, are likely correlating with pulmonary artery systolic pressure, thus potential markers of the development of altitude illness. Established drug treatments include acetazolamide, nifedipine, and dexamethasone. Drugs with a potential to reduce the risk of developing AMS include nitrate supplements, propagators of nitric oxide, and supplemental iron. The role of exercise in the development of altitude illness remains hotly debated, and it appears that the intensity of exercise is more important than the exercise itself. Finally, despite copious studies demonstrating the value of preacclimatization in reducing the risk of altitude illness and improving performance, an optimal protocol to preacclimatize an individual remains elusive. Keywords: hypoxia, acute mountain sickness, acclimatization, biomarkers, preacclimatization

  12. The STAR Data Reporting Guidelines for Clinical High Altitude Research.

    Science.gov (United States)

    Brodmann Maeder, Monika; Brugger, Hermann; Pun, Matiram; Strapazzon, Giacomo; Dal Cappello, Tomas; Maggiorini, Marco; Hackett, Peter; Bärtsch, Peter; Swenson, Erik R; Zafren, Ken

    2018-03-01

    Brodmann Maeder, Monika, Hermann Brugger, Matiram Pun, Giacomo Strapazzon, Tomas Dal Cappello, Marco Maggiorini, Peter Hackett, Peter Baärtsch, Erik R. Swenson, Ken Zafren (STAR Core Group), and the STAR Delphi Expert Group. The STARdata reporting guidelines for clinical high altitude research. High AltMedBiol. 19:7-14, 2018. The goal of the STAR (STrengthening Altitude Research) initiative was to produce a uniform set of key elements for research and reporting in clinical high-altitude (HA) medicine. The STAR initiative was inspired by research on treatment of cardiac arrest, in which the establishment of the Utstein Style, a uniform data reporting protocol, substantially contributed to improving data reporting and subsequently the quality of scientific evidence. The STAR core group used the Delphi method, in which a group of experts reaches a consensus over multiple rounds using a formal method. We selected experts in the field of clinical HA medicine based on their scientific credentials and identified an initial set of parameters for evaluation by the experts. Of 51 experts in HA research who were identified initially, 21 experts completed both rounds. The experts identified 42 key parameters in 5 categories (setting, individual factors, acute mountain sickness and HA cerebral edema, HA pulmonary edema, and treatment) that were considered essential for research and reporting in clinical HA research. An additional 47 supplemental parameters were identified that should be reported depending on the nature of the research. The STAR initiative, using the Delphi method, identified a set of key parameters essential for research and reporting in clinical HA medicine.

  13. Response of Eyjafjallajökull, Torfajökull and Tindfjallajökull ice caps in Iceland to regional warming, deduced by remote sensing

    Directory of Open Access Journals (Sweden)

    Jørgen Dall

    2011-07-01

    Full Text Available We assess the volume change and mass balance of three ice caps in southern Iceland for two periods, 1979–1984 to 1998 and 1998 to 2004, by comparing digital elevation models (DEMs. The ice caps are Eyjafjallajökull (ca. 81 km2, Tindfjallajökull (ca. 15 km2 and Torfajökull (ca. 14 km2. The DEMs were compiled using aerial photographs from 1979 to 1984, airborne Synthetic Aperture Radar (SAR images obtained in 1998 and two image pairs from the SPOT 5 satellite's high-resolution stereoscopic (HRS instrument acquired in 2004. The ice-free part of the accurate DEM from 1998 was used as a reference map for co-registration and correction of the vertical offset of the other DEMs. The average specific mass balance was estimated from the mean elevation difference between glaciated areas of the DEMs. The glacier mass balance declined significantly between the two periods: from −0.2 to 0.2 m yr−1 w. eq. during the earlier period (1980s through 1998 to −1.8 to −1.5 m yr−1 w. eq. for the more recent period (1998–2004. The declining mass balance is consistent with increased temperature over the two periods. The low mass balance and the small accumulation area ratio of Tindfjallajökull and Torfajökull indicate that they will disappear if the present-day climate continues. The future lowering rate of Eyjafjallajökull will, however, be influenced by the 2010 subglacial eruption in the Eyjafjallajökull volcano.

  14. Atmospheric depositions of natural and anthropogenic trace elements on the Guliya ice cap (northwestern Tibetan Plateau) during the last 340 years

    Science.gov (United States)

    Sierra-Hernández, M. Roxana; Gabrielli, Paolo; Beaudon, Emilie; Wegner, Anna; Thompson, Lonnie G.

    2018-03-01

    A continuous record of 29 trace elements (TEs) has been constructed between 1650 and 1991 CE (Common Era) from an ice core retrieved in 1992 from the Guliya ice cap, on the northwestern Tibetan Plateau. Enrichments of Pb, Cd, Zn and Sb were detected during the second half of the 19th century and the first half of the 20th century (∼1850-1950) while enrichments of Sn (1965-1991), Cd and Pb (1975-1991) were detected during the second half of the 20th century. The EFs increased significantly by 20% for Cd and Sb, and by 10% for Pb and Zn during 1850-1950 relative to the pre-1850s. Comparisons of the Guliya TEs data with other ice core-derived and production/consumption data suggest that Northern Hemisphere coal combustion (primarily in Western Europe) is the likely source of Pb, Cd, Zn, and Sb during the 1850-1950 period. Coal combustion in Europe declined as oil replaced coal as the primary energy source. The European shift from coal to oil may have contributed to the observed Sn enrichment in ∼1965 (60% EF increase in 1975-1991), although regional fossil fuel combustion (coal and leaded gasoline) from western China, Central Asia, and South Asia (India, Nepal), as well as Sn mining/smelting in Central Asia, may also be possible sources. The post-1975 Cd and Pb enrichments (40% and 20% EF increase respectively in 1975-1991) may reflect emissions from phosphate fertilizers, fossil fuel combustion, and/or non-ferrous metal production, from western China, Central Asia, and/or South Asia. Leaded gasoline is likely to have also contributed to the post-1975 Pb enrichment observed in this record. The results strongly suggest that the Guliya ice cap has recorded long-distance emissions from coal combustion since the 1850s with more recent contributions from regional agriculture, mining, and/or fossil fuel combustion. This new Guliya ice core record of TEs fills a geographical gap in the reconstruction of the pollution history of this region that extends well beyond modern

  15. Three plasma metabolite signatures for diagnosing high altitude pulmonary edema

    Science.gov (United States)

    Guo, Li; Tan, Guangguo; Liu, Ping; Li, Huijie; Tang, Lulu; Huang, Lan; Ren, Qian

    2015-10-01

    High-altitude pulmonary edema (HAPE) is a potentially fatal condition, occurring at altitudes greater than 3,000 m and affecting rapidly ascending, non-acclimatized healthy individuals. However, the lack of biomarkers for this disease still constitutes a bottleneck in the clinical diagnosis. Here, ultra-high performance liquid chromatography coupled with Q-TOF mass spectrometry was applied to study plasma metabolite profiling from 57 HAPE and 57 control subjects. 14 differential plasma metabolites responsible for the discrimination between the two groups from discovery set (35 HAPE subjects and 35 healthy controls) were identified. Furthermore, 3 of the 14 metabolites (C8-ceramide, sphingosine and glutamine) were selected as candidate diagnostic biomarkers for HAPE using metabolic pathway impact analysis. The feasibility of using the combination of these three biomarkers for HAPE was evaluated, where the area under the receiver operating characteristic curve (AUC) was 0.981 and 0.942 in the discovery set and the validation set (22 HAPE subjects and 22 healthy controls), respectively. Taken together, these results suggested that this composite plasma metabolite signature may be used in HAPE diagnosis, especially after further investigation and verification with larger samples.

  16. Nationwide network of total solar eclipse high altitude balloon flights

    Science.gov (United States)

    Des Jardins, A. C.

    2017-12-01

    Three years ago we envisioned tapping into the strength of the National Space Grant Program to make the most of a rare astronomical event to engage the general public through education and to create meaningful long-lasting partnerships with other private and public entities. We believe strongly in giving student participants career-making opportunities through the use of the most cutting edge tools, resources, and communication. The NASA Space Grant network was in a unique position to engage the public in the eclipse in an awe-inspiring and educational way at a surprisingly small cost. In addition to public engagement, the multidisciplinary project presented an in-depth hands-on learning opportunity for the thousands of student participants. The project used a network of high altitude ballooning teams positioned along the path of totality from Oregon to South Carolina to conduct coordinated collaborative activities during the eclipse. These activities included 1) capturing and streaming live video of the eclipse from near space, 2) partnering with NASA Ames on a space biology experiment, and 3) conducting high-resolution atmospheric radiosonde measurements. This presentation will summarize the challenges, results, lessons learned, and professional evaluation from developing, training, and coordinating the collaboration. Details of the live streaming HD video and radiosonde activities are described in separate submissions to this session.

  17. Radiation doses at high altitudes and during space flights

    International Nuclear Information System (INIS)

    Spurny, F.

    2001-01-01

    There are three main sources of radiation exposure during space flights and at high altitudes--galactic cosmic radiation, solar cosmic radiation and radiation of the earth's radiation belt. Their basic characteristics are presented in the first part of this paper.Man's exposure during space flights is discussed in the second part of the paper. Particular attention is devoted to the quantitative and qualitative characteristics of the radiation exposure on near-earth orbits: both theoretical estimation as well as experimental data are presented. Some remarks on radiation protection rules on-board space vehicles are also given.The problems connected with the radiation protection of air crew and passengers of subsonic and supersonic air transport are discussed in the last part of the paper. General characteristics of on-board radiation fields and their variations with flight altitude, geomagnetic parameters of a flight and the solar activity are presented, both based on theoretical estimates and experimental studies. The questions concerning air crew and passenger radiation protection arising after the publication of ICRP 60 recommendation are also discussed. Activities of different institutions relevant to the topic are mentioned; strategies to manage and check this type of radiation exposure are presented and discussed. Examples of results based on the author's personal experience are given, analyzed and discussed. (author)

  18. Isothermal pumping analysis for high-altitude tethered balloons.

    Science.gov (United States)

    Kuo, Kirsty A; Hunt, Hugh E M

    2015-06-01

    High-altitude tethered balloons have potential applications in communications, surveillance, meteorological observations and climate engineering. To maintain balloon buoyancy, power fuel cells and perturb atmospheric conditions, fluids could be pumped from ground level to altitude using the tether as a hose. This paper examines the pumping requirements of such a delivery system. Cases considered include delivery of hydrogen, sulfur dioxide (SO2) and powders as fluid-based slurries. Isothermal analysis is used to determine the variation of pressures and velocities along the pipe length. Results show that transport of small quantities of hydrogen to power fuel cells and maintain balloon buoyancy can be achieved at pressures and temperatures that are tolerable in terms of both the pipe strength and the current state of pumping technologies. To avoid solidification, transport of SO2 would require elevated temperatures that cannot be tolerated by the strength fibres in the pipe. While the use of particle-based slurries rather than SO2 for climate engineering can reduce the pipe size significantly, the pumping pressures are close to the maximum bursting pressure of the pipe.

  19. A method for sampling microbial aerosols using high altitude balloons.

    Science.gov (United States)

    Bryan, N C; Stewart, M; Granger, D; Guzik, T G; Christner, B C

    2014-12-01

    Owing to the challenges posed to microbial aerosol sampling at high altitudes, very little is known about the abundance, diversity, and extent of microbial taxa in the Earth-atmosphere system. To directly address this knowledge gap, we designed, constructed, and tested a system that passively samples aerosols during ascent through the atmosphere while tethered to a helium-filled latex sounding balloon. The sampling payload is ~ 2.7 kg and comprised of an electronics box and three sampling chambers (one serving as a procedural control). Each chamber is sealed with retractable doors that can be commanded to open and close at designated altitudes. The payload is deployed together with radio beacons that transmit GPS coordinates (latitude, longitude and altitude) in real time for tracking and recovery. A cut mechanism separates the payload string from the balloon at any desired altitude, returning all equipment safely to the ground on a parachute. When the chambers are opened, aerosol sampling is performed using the Rotorod® collection method (40 rods per chamber), with each rod passing through 0.035 m3 per km of altitude sampled. Based on quality control measurements, the collection of ~ 100 cells rod(-1) provided a 3-sigma confidence level of detection. The payload system described can be mated with any type of balloon platform and provides a tool for characterizing the vertical distribution of microorganisms in the troposphere and stratosphere. Copyright © 2014 Elsevier B.V. All rights reserved.

  20. Development and testing of airfoils for high-altitude aircraft

    Science.gov (United States)

    Drela, Mark (Principal Investigator)

    1996-01-01

    Specific tasks included airfoil design; study of airfoil constraints on pullout maneuver; selection of tail airfoils; examination of wing twist; test section instrumentation and layout; and integrated airfoil/heat-exchanger tests. In the course of designing the airfoil, specifically for the APEX test vehicle, extensive studies were made over the Mach and Reynolds number ranges of interest. It is intended to be representative of airfoils required for lightweight aircraft operating at extreme altitudes, which is the primary research objective of the APEX program. Also considered were thickness, pitching moment, and off-design behavior. The maximum ceiling parameter M(exp 2)C(sub L) value achievable by the Apex-16 airfoil was found to be a strong constraint on the pullout maneuver. The NACA 1410 and 2410 airfoils (inverted) were identified as good candidates for the tail, with predictable behavior at low Reynolds numbers and good tolerance to flap deflections. With regards to wing twist, it was decided that a simple flat wing was a reasonable compromise. The test section instrumentation consisted of surface pressure taps, wake rakes, surface-mounted microphones, and skin-friction gauges. Also, a modest wind tunnel test was performed for an integrated airfoil/heat-exchanger configuration, which is currently on Aurora's 'Theseus' aircraft. Although not directly related to the APEX tests, the aerodynamics or heat exchangers has been identified as a crucial aspect of designing high-altitude aircraft and hence is relevant to the ERAST program.

  1. Assessing water resources under climate change in high-altitude catchments: a methodology and an application in the Italian Alps

    Science.gov (United States)

    Aili, T.; Soncini, A.; Bianchi, A.; Diolaiuti, G.; D'Agata, C.; Bocchiola, D.

    2018-01-01

    Assessment of the future water resources in the Italian Alps under climate change is required, but the hydrological cycle of the high-altitude catchments therein is poorly studied and little understood. Hydrological monitoring and modeling in the Alps is difficult, given the lack of first hand, site specific data. Here, we present a method to model the hydrological cycle of poorly monitored high-altitude catchments in the Alps, and to project forward water resources availability under climate change. Our method builds on extensive experience recently and includes (i) gathering data of climate, of cryospheric variables, and of hydrological fluxes sparsely available; (ii) robust physically based glacio-hydrological modeling; and (iii) using glacio-hydrological projections from GCM models. We apply the method in the Mallero River, in the central (Retiche) Alps of Italy. The Mallero river covers 321 km2, with altitude between 310 and 4015 m a.s.l., and it has 27 km2 of ice cover. The glaciers included in the catchment underwent large mass loss recently, thus Mallero is largely paradigmatic of the present situation of Alpine rivers. We set up a spatially explicit glacio-hydrological model, describing the cryospheric evolution and the hydrology of the area during a control run CR, from 1981 to 2007. We then gather climate projections until 2100 from three Global Climate Models of the IPCC AR5 under RCP2.6, RCP4.5, and RCP8.5. We project forward flow statistics, flow components (rainfall, snow melt, ice melt), ice cover, and volume for two reference decades, namely 2045-2054 and 2090-2099. We foresee reduction of the ice bodies from - 62 to - 98% in volume (year 2100 vs year 1981), and subsequent large reduction of ice melt contribution to stream flows (from - 61 to - 88%, 2100 vs CR). Snow melt, now covering 47% of the stream flows yearly, would also be largely reduced (from - 19 to - 56%, 2100 vs CR). The stream flows will decrease on average at 2100 (from + 1 to - 25

  2. Volume changes of Vatnajökull ice cap, Iceland, due to surface mass balance, ice flow, and subglacial melting at geothermal areas

    DEFF Research Database (Denmark)

    Magnússon, Eyjólfur; Björnson, Helgi; Dall, Jørgen

    2005-01-01

    We present observed changes in the geometry of western Vatnajökull over a period of about ten years which are caused by the surface mass balance, ice flow (both during surges and quiescent periods), and basal melting due to geothermal and volcanic activity. Comparison of two digital elevation...

  3. High-Altitude-Induced alterations in Gut-Immune Axis: A review.

    Science.gov (United States)

    Khanna, Kunjan; Mishra, K P; Ganju, Lilly; Kumar, Bhuvnesh; Singh, Shashi Bala

    2018-03-04

    High-altitude sojourn above 8000 ft is increasing day by day either for pilgrimage, mountaineering, holidaying or for strategic reasons. In India, soldiers are deployed to these high mountains for their duty or pilgrims visit to the holy places, which are located at very high altitude. A large population also resides permanently in high altitude regions. Every year thousands of pilgrims visit Holy cave of Shri Amarnath ji, which is above 15 000 ft. The poor acclimatization to high altitude may cause alteration in immunity. The low oxygen partial pressure may cause alterations in gut microbiota, which may cause changes in gut immunity. Effect of high altitude on gut-associated mucosal system is new area of research. Many studies have been carried out to understand the physiology and immunology behind the high-altitude-induced gut problems. Few interventions have also been discovered to circumvent the problems caused due to high-altitude conditions. In this review, we have discussed the effects of high-altitude-induced changes in gut immunity particularly peyer's patches, NK cells and inflammatory cytokines, secretary immunoglobulins and gut microbiota. The published articles from PubMed and Google scholar from year 1975 to 2017 on high-altitude hypoxia and gut immunity are cited in this review.

  4. A brief introduction to high altitude nuclear explosion and a review on high altitude nuclear tests of usa and former USSR

    International Nuclear Information System (INIS)

    Sun Jingwen

    1999-11-01

    The author briefly introduces some knowledge about high altitude nuclear explosion (HANE) and presents a general review on high altitude nuclear tests of USA and former USSR. Physical phenomenon generated by HANE is given. The effects of HANE on space flyer, artificial satellite and communication are discussed. Some aspects of a mechanism of antimissile for HANE are described and the effect and role of HANE for USA and USSR are reviewed

  5. Assessing lahars from ice-capped volcanoes using ASTER satellite data, the SRTM DTM and two different flow models: case study on Iztaccíhuatl (Central Mexico

    Directory of Open Access Journals (Sweden)

    D. Schneider

    2008-06-01

    Full Text Available Lahars frequently affect the slopes of ice-capped volcanoes. They can be triggered by volcano-ice interactions during eruptions but also by processes such as intense precipitation or by outbursts of glacial water bodies not directly related to eruptive activity. We use remote sensing, GIS and lahar models in combination with ground observations for an initial lahar hazard assessment on Iztaccíhuatl volcano (5230 m a.s.l., considering also possible future developments of the glaciers on the volcano. Observations of the glacial extent are important for estimations of future hazard scenarios, especially in a rapidly changing tropical glacial environment. In this study, analysis of the glaciers on Iztaccíhuatl shows a dramatic retreat during the last 150 years: the glaciated area in 2007 corresponds to only 4% of the one in 1850 AD and the glaciers are expected to survive no later than the year 2020. Most of the glacial retreat is considered to be related to climate change but in-situ observations suggest also that geo- and hydrothermal heat flow at the summit-crater area can not be ruled out, as emphasized by fumarolic activity documented in a former study. However, development of crater lakes and englacial water reservoirs are supposed to be a more realistic scenario for lahar generation than sudden ice melting by rigorous volcano-ice interaction. Model calculations show that possible outburst floods have to be larger than ~5×105 m3 or to achieve an H/L ratio (Height/runout Length of 0.2 and lower in order to reach the populated lower flanks. This threshold volume equals 2.4% melted ice of Iztaccíhuatl's total ice volume in 2007, assuming 40% water and 60% volumetric debris content of a potential lahar. The model sensitivity analysis reveals important effects of the generic type of the Digital Terrain Model (DTM used on the results. As a consequence, the predicted affected areas can vary significantly. For such

  6. Iridium: Global OTH data communications for high altitude scientific ballooning

    Science.gov (United States)

    Denney, A.

    While the scientific community is no stranger to embracing commercially available technologies, the growth and availability of truly affordable cutting edge technologies is opening the door to an entirely new means of global communications. For many years high altitude ballooning has provided science an alternative to costly satellite based experimental platforms. As with any project, evolution becomes an integral part of development. Specifically in the NSBF ballooning program, where flight durations have evolved from the earlier days of hours to several weeks and plans are underway to provide missions up to 100 days. Addressing increased flight durations, the harsh operational environment, along with cumbersome and outdated systems used on existing systems, such as the balloon vehicles Support Instrumentation Package (SIP) and ground-based systems, a new Over-The-Horizon (OTH) communications medium is sought. Current OTH equipment planning to be phased-out include: HF commanding systems, ARGOS PTT telemetry downlinks and INMARSAT data terminals. Other aspects up for review in addition to the SIP to utilize this communications medium include pathfinder balloon platforms - thereby, adding commanding abilities and increased data rates, plus providing a package for ultra-small experiments to ride aloft. Existing communication systems employed by the National Scientific Balloon Facility ballooning program have been limited not only by increased cost, slow data rates and "special government use only" services such as TDRSS (Tracking and Data Relay Satellite System), but have had to make special provisions to geographical flight location. Development of the Support Instrumentation Packages whether LDB (Long Duration Balloon), ULDB (Ultra Long Duration Balloon) or conventional ballooning have been plagued by non-standard systems configurations requiring additional support equipment for different regions and missions along with a myriad of backup for redundancy. Several

  7. Circum-Arctic Changes in the Flow of Glaciers and Ice Caps from Satellite SAR Data between the 1990s and 2017

    Directory of Open Access Journals (Sweden)

    Tazio Strozzi

    2017-09-01

    Full Text Available We computed circum-Arctic surface velocity maps of glaciers and ice caps over the Canadian Arctic, Svalbard and the Russian Arctic for at least two times between the 1990s and 2017 using satellite SAR data. Our analyses are mainly performed with offset-tracking of ALOS-1 PALSAR-1 (2007–2011 and Sentinel-1 (2015–2017 data. In certain cases JERS-1 SAR (1994–1998, TerraSAR-X (2008–2012, Radarsat-2 (2009–2016 and ALOS-2 PALSAR-2 (2015–2016 data were used to fill-in spatial or temporal gaps. Validation of the latest Sentinel-1 results was accomplished by means of SAR data at higher spatial resolution (Radarsat-2 Wide Ultra Fine and ground-based measurements. In general, we observe a deceleration of flow velocities for the major tidewater glaciers in the Canadian Arctic and an increase in frontal velocity along with a retreat of frontal positions over Svalbard and the Russian Arctic. However, all regions have strong accelerations for selected glaciers. The latter developments can be well traced based on the very high temporal sampling of Sentinel-1 acquisitions since 2015, revealing new insights in glacier dynamics. For example, surges on Spitsbergen (e.g., Negribreen, Nathorsbreen, Penckbreen and Strongbreen have a different characteristic and timing than those over Eastern Austfonna and Edgeoya (e.g., Basin 3, Basin 2 and Stonebreen. Events similar to those ongoing on Eastern Austofonna were also observed over the Vavilov Ice Cap on Severnaya Zemlya and possibly Simony Glacier on Franz-Josef Land. Collectively, there seems to be a recently increasing number of glaciers with frontal destabilization over Eastern Svalbard and the Russian Arctic compared to the 1990s.

  8. Oviposition of aquatic insects in a tropical high altitude stream.

    Science.gov (United States)

    Rios-Touma, Blanca; Encalada, A C; Prat, N

    2012-12-01

    The persistence of aquatic insect populations in streams depends on the recruitment of larval populations from egg masses deposited by adults, especially after disturbance. However, recruitment of aquatic populations by oviposition is a process that remains unstudied in streams and rivers. The objectives of our study were to document flying and oviposition patterns of aquatic insects in a high altitude tropical stream during both dry and wet seasons. In particular we studied 1) richness and abundance of adult forms of aquatic insects flying and ovipositing; 2) number of eggs (oviposition pattern), egg mass identity, and morphology; and 3) substrate preferences by ovipositing females. We found 2,383 aquatic insects corresponding to 28 families, with dipterans representing 89% of total individuals collected. Adult insects had lower richness (28 taxa) than larval diversity (up to 52 taxa) and distinct community composition. Richness and relative abundance of most taxa (adults) were not significantly different between seasons, behaviors, diel period, or all three. During both sampling periods we found females with eggs in a total of 15 different families (13 in the dry season and 14 in the wet season). There were no significant differences in the proportion of females with eggs between seasons, diel periods, or different behaviors (flying versus ovipositing traps) of the different female taxa. Few types of egg masses were found in rocks at the stream during both seasons, and most egg masses found corresponded to families Baetidae and Chironomidae. Finally, we provide the first description of eggs masses (size, shape, color, and number of eggs per female) of gravid females (10 taxa) and those found in the stream substrate (six taxa) of Andean macroinvertebrates. This is the first study reporting oviposition, adult diversity, and oviposition patterns of aquatic insects in the Andean region.

  9. The HAMMER: High altitude multiple mission environmental researcher

    Science.gov (United States)

    Hayashi, Darren; Zylla, Cara; Amaro, Ernesto; Colin, Phil; Klause, Thomas; Lopez, Bernardo; Williamson, Danna

    1991-01-01

    At the equator, the ozone layer ranges from 65,000 to 130,000+ feet which is beyond the capabilities of the ER-2, NASA's current high altitude reconnaissance aircraft. The Universities Space Research Association, in cooperation with NASA, is sponsoring an undergraduate program which is geared to designing an aircraft that can study the ozone layer at the equator. This aircraft must be able to satisfy four mission profiles. Mission one is a polar mission which ranges from Chile to the South Pole and back to Chile, a total range of 6000 n. mi. at 100,000 feet with a 2500 lb. payload. The second mission is also a polar mission with a decreased altitude of 70,000 feet and an increased payload of 4000 lb. For the third mission, the aircraft will take-off at NASA Ames, cruise at 100,000 feet carrying a 2500 lb. payload, and land in Puerto Montt, Chile. The final mission requires the aircraft to take-off at NASA Ames, cruise at 100,000 feet with a 1000 lb. payload, make an excursion to 120,000 feet, and land at Howard AFB, Panama. All three missions require that a subsonic Mach number is maintained due to constraints imposed by the air sampling equipment. The aircraft need not be manned for all four missions. Three aircraft configurations were determined to be the most suitable for meeting the above requirements. The performance of each configuration is analyzed to investigate the feasibility of the project requirements. In the event that a requirement can not be obtained within the given constraints, recommendations for proposal modifications are given.

  10. High Altitude Aerial Natural Gas Leak Detection System

    Energy Technology Data Exchange (ETDEWEB)

    Richard T. Wainner; Mickey B. Frish; B. David Green; Matthew C. Laderer; Mark G. Allen; Joseph R. Morency

    2006-12-31

    The objective of this program was to develop and demonstrate a cost-effective and power-efficient advanced standoff sensing technology able to detect and quantify, from a high-altitude (> 10,000 ft) aircraft, natural gas leaking from a high-pressure pipeline. The advanced technology is based on an enhanced version of the Remote Methane Leak Detector (RMLD) platform developed previously by Physical Sciences Inc. (PSI). The RMLD combines a telecommunications-style diode laser, fiber-optic components, and low-cost DSP electronics with the well-understood principles of Wavelength Modulation Spectroscopy (WMS), to indicate the presence of natural gas located between the operator and a topographic target. The transceiver transmits a laser beam onto a topographic target and receives some of the laser light reflected by the target. The controller processes the received light signal to deduce the amount of methane in the laser's path. For use in the airborne platform, we modified three aspects of the RMLD, by: (1) inserting an Erbium-doped optical fiber laser amplifier to increase the transmitted laser power from 10 mW to 5W; (2) increasing the optical receiver diameter from 10 cm to 25 cm; and (3) altering the laser wavelength from 1653 nm to 1618 nm. The modified RMLD system provides a path-integrated methane concentration sensitivity {approx}5000 ppm-m, sufficient to detect the presence of a leak from a high capacity transmission line while discriminating against attenuation by ambient methane. In ground-based simulations of the aerial leak detection scenario, we demonstrated the ability to measure methane leaks within the laser beam path when it illuminates a topographic target 2000 m away. We also demonstrated simulated leak detection from ranges of 200 m using the 25 cm optical receiver without the fiber amplifier.

  11. Characteristics of high altitude oxygen ion energization and outflow as observed by Cluster: a statistical study

    Energy Technology Data Exchange (ETDEWEB)

    Nilsson, H.; Waara, M.; Arvelius, S.; Yamauchi, M.; Lundin, R. [Inst. of Space Physics, Kiruna (Sweden); Marghitu, O. [Max-Planck-Inst. fuer Extraterrestriche Physik, Garching (Germany); Inst. for Space Sciences, Bucharest (Romania); Bouhram, M. [Max-Planck-Inst. fuer Extraterrestriche Physik, Garching (Germany); CETP-CNRS, Saint-Maur (France); Hobara, Y. [Inst. of Space Physics, Kiruna (Sweden); Univ. of Sheffield, Sheffield (United Kingdom); Reme, H.; Sauvaud, J.A.; Dandouras, I. [Centre d' Etude Spatiale des Rayonnements, Toulouse (France); Balogh, A. [Imperial Coll. of Science, Technology and Medicine, London (United Kingdom); Kistler, L.M. [Univ. of New Hampshire, Durham (United States); Klecker, B. [Max-Planck-Inst. fuer Extraterrestriche Physik, Garching (Germany); Carlson, C.W. [Space Science Lab., Univ. of California, Berkeley (United States); Bavassano-Cattaneo, M.B. [Ist. di Fisica dello Spazio Interplanetario, Roma (Italy); Korth, A. [Max-Planck-Inst. fuer Sonnensystemforschung, Katlenburg-Lindau (Germany)

    2006-07-01

    The results of a statistical study of oxygen ion outflow using cluster data obtained at high altitude above the polar cap is reported. Moment data for both hydrogen ions (H{sup +}) and oxygen ions (O{sup +}) from 3 years (2001-2003) of spring orbits (January to May) have been used. The altitudes covered were mainly in the range 5-12 R{sub E} geocentric distance. It was found that O{sup +} is significantly transversely energized at high altitudes, indicated both by high perpendicular temperatures for low magnetic field values as well as by a tendency towards higher perpendicular than parallel temperature distributions for the highest observed temperatures. The O{sup +} parallel bulk velocity increases with altitude in particular for the lowest observed altitude intervals. O{sup +} parallel bulk velocities in excess of 60 km s{sup -1} were found mainly at higher altitudes corresponding to magnetic field strengths of less than 100 nT. For the highest observed parallel bulk velocities of O{sup +} the thermal velocity exceeds the bulk velocity, indicating that the beam-like character of the distribution is lost. The parallel bulk velocity of the H{sup +} and O{sup +} was found to typically be close to the same throughout the observation interval when the H{sup +} bulk velocity was calculated for all pitch-angles. When the H{sup +} bulk velocity was calculated for upward moving particles only the H{sup +} parallel bulk velocity was typically higher than that of O{sup +}. The parallel bulk velocity is close to the same for a wide range of relative abundance of the two ion species, including when the O{sup +} ions dominates. The thermal velocity of O{sup +} was always well below that of H{sup +}. Thus perpendicular energization that is more effective for O{sup +} takes place, but this is not enough to explain the close to similar parallel velocities. Further parallel acceleration must occur. The results presented constrain the models of perpendicular heating and parallel

  12. Characteristics of high altitude oxygen ion energization and outflow as observed by Cluster: a statistical study

    Directory of Open Access Journals (Sweden)

    H. Nilsson

    2006-05-01

    Full Text Available The results of a statistical study of oxygen ion outflow using Cluster data obtained at high altitude above the polar cap is reported. Moment data for both hydrogen ions (H+ and oxygen ions (O+ from 3 years (2001-2003 of spring orbits (January to May have been used. The altitudes covered were mainly in the range 5–12 RE geocentric distance. It was found that O+ is significantly transversely energized at high altitudes, indicated both by high perpendicular temperatures for low magnetic field values as well as by a tendency towards higher perpendicular than parallel temperature distributions for the highest observed temperatures. The O+ parallel bulk velocity increases with altitude in particular for the lowest observed altitude intervals. O+ parallel bulk velocities in excess of 60 km s-1 were found mainly at higher altitudes corresponding to magnetic field strengths of less than 100 nT. For the highest observed parallel bulk velocities of O+ the thermal velocity exceeds the bulk velocity, indicating that the beam-like character of the distribution is lost. The parallel bulk velocity of the H+ and O+ was found to typically be close to the same throughout the observation interval when the H+ bulk velocity was calculated for all pitch-angles. When the H+ bulk velocity was calculated for upward moving particles only the H+ parallel bulk velocity was typically higher than that of O+. The parallel bulk velocity is close to the same for a wide range of relative abundance of the two ion species, including when the O+ ions dominates. The thermal velocity of O+ was always well below that of H+. Thus perpendicular energization that is more effective for O+ takes place, but this is not enough to explain the close to similar parallel velocities. Further

  13. Characteristics of high altitude oxygen ion energization and outflow as observed by Cluster: a statistical study

    Directory of Open Access Journals (Sweden)

    H. Nilsson

    2006-05-01

    Full Text Available The results of a statistical study of oxygen ion outflow using Cluster data obtained at high altitude above the polar cap is reported. Moment data for both hydrogen ions (H+ and oxygen ions (O+ from 3 years (2001-2003 of spring orbits (January to May have been used. The altitudes covered were mainly in the range 5–12 RE geocentric distance. It was found that O+ is significantly transversely energized at high altitudes, indicated both by high perpendicular temperatures for low magnetic field values as well as by a tendency towards higher perpendicular than parallel temperature distributions for the highest observed temperatures. The O+ parallel bulk velocity increases with altitude in particular for the lowest observed altitude intervals. O+ parallel bulk velocities in excess of 60 km s-1 were found mainly at higher altitudes corresponding to magnetic field strengths of less than 100 nT. For the highest observed parallel bulk velocities of O+ the thermal velocity exceeds the bulk velocity, indicating that the beam-like character of the distribution is lost. The parallel bulk velocity of the H+ and O+ was found to typically be close to the same throughout the observation interval when the H+ bulk velocity was calculated for all pitch-angles. When the H+ bulk velocity was calculated for upward moving particles only the H+ parallel bulk velocity was typically higher than that of O+. The parallel bulk velocity is close to the same for a wide range of relative abundance of the two ion species, including when the O+ ions dominates. The thermal velocity of O+ was always well below that of H+. Thus perpendicular energization that is more effective for O+ takes place, but this is not enough to explain the close to similar parallel velocities. Further parallel acceleration must occur. The results presented constrain the models of perpendicular heating and parallel acceleration. In particular centrifugal acceleration of the outflowing ions, which may

  14. Cervical Cap

    Science.gov (United States)

    ... Videos for Educators Search English Español The Cervical Cap KidsHealth / For Teens / The Cervical Cap What's in ... Call the Doctor? Print What Is a Cervical Cap? A cervical cap is a small cup made ...

  15. Hyperbaric oxygen therapy ameliorates acute brain injury after porcine intracerebral hemorrhage at high altitude.

    Science.gov (United States)

    Zhu, Hai-tao; Bian, Chen; Yuan, Ji-chao; Liao, Xiao-jun; Liu, Wei; Zhu, Gang; Feng, Hua; Lin, Jiang-kai

    2015-06-15

    Intracerebral hemorrhage (ICH) at high altitude is not well understood to date. This study investigates the effects of high altitude on ICH, and examines the acute neuroprotection of hyperbaric oxygen (HBO) therapy against high-altitude ICH. Minipigs were placed in a hypobaric chamber for 72 h before the operation. ICH was induced by an infusion of autologous arterial blood (3 ml) into the right basal ganglia. Animals in the high-altitude ICH group received HBO therapy (2.5 ATA for 60 min) 30 min after ICH. Blood gas, blood glucose and brain tissue oxygen partial pressure (PbtO2) were monitored continuously for animals from all groups, as were microdialysis products including glucose, lactate, pyruvate and glutamate in perihematomal tissue from 3 to 12 h post-ICH. High-altitude ICH animals showed significantly lower PbtO2, higher lactate/pyruvate ratio (LPR) and glutamate levels than low-altitude ICH animals. More severe neurological deficits, brain edema and neuronal damage were also observed in high-altitude ICH. After HBO therapy, PbtO2 was significantly increased and LPR and glutamate levels were significantly decreased. Brain edema, neurological deficits and neuronal damage were also ameliorated. The data suggested a more serious disturbance of tissue oxygenation and cerebral metabolism in the acute stage after ICH at high altitude. Early HBO treatment reduced acute brain injury, perhaps through a mechanism involving the amelioration of the derangement of cerebral oxygenation and metabolism following high-altitude ICH.

  16. Effect of oxygen supplementation in a hatchery at high altitude and ...

    African Journals Online (AJOL)

    The objective of this study was to investigate the effect of oxygen supplementation on broiler eggs in a hatchery at high altitude on the growth performance and ascites syndrome of broilers reared at low altitude. The treatment groups were low altitude with no oxygen supplemented in the hatchery (LA-NOX); high altitude with ...

  17. Oxidative DNA damage and repair in skeletal muscle of humans exposed to high-altitude hypoxia

    DEFF Research Database (Denmark)

    Lundby, Carsten; Pilegaard, Henriette; van Hall, Gerrit

    2003-01-01

    Recent research suggests that high-altitude hypoxia may serve as a model for prolonged oxidative stress in healthy humans. In this study, we investigated the consequences of prolonged high-altitude hypoxia on the basal level of oxidative damage to nuclear DNA in muscle cells, a major oxygen-consuming...

  18. Simulating the roles of crevasse routing of surface water and basal friction on the surge evolution of Basin 3, Austfonna ice cap

    Science.gov (United States)

    Gong, Yongmei; Zwinger, Thomas; Åström, Jan; Altena, Bas; Schellenberger, Thomas; Gladstone, Rupert; Moore, John C.

    2018-05-01

    The marine-terminating outlet in Basin 3, Austfonna ice cap, has been accelerating since the mid-1990s. Stepwise multi-annual acceleration associated with seasonal summer speed-up events was observed before the outlet entered the basin-wide surge in autumn 2012. We used multiple numerical models to explore hydrologic activation mechanisms for the surge behaviour. A continuum ice dynamic model was used to invert basal friction coefficient distributions using the control method and observed surface velocity data between April 2012 and July 2014. This has provided input to a discrete element model capable of simulating individual crevasses, with the aim of finding locations where meltwater entered the glacier during the summer and reached the bed. The possible flow paths of surface meltwater reaching the glacier bed as well as those of meltwater produced at the bed were calculated according to the gradient of the hydraulic potential. The inverted friction coefficients show the unplugging of the stagnant ice front and expansion of low-friction regions before the surge reached its peak velocity in January 2013. Crevasse distribution reflects the basal friction pattern to a high degree. The meltwater reaches the bed through the crevasses located above the margins of the subglacial valley and the basal melt that is generated mainly by frictional heating flows either to the fast-flowing units or potentially accumulates in an overdeepened region. Based on these results, the mechanisms facilitated by basal meltwater production, crevasse opening and the routing of meltwater to the bed are discussed for the surge in Basin 3.

  19. Simulating the roles of crevasse routing of surface water and basal friction on the surge evolution of Basin 3, Austfonna ice cap

    Directory of Open Access Journals (Sweden)

    Y. Gong

    2018-05-01

    Full Text Available The marine-terminating outlet in Basin 3, Austfonna ice cap, has been accelerating since the mid-1990s. Stepwise multi-annual acceleration associated with seasonal summer speed-up events was observed before the outlet entered the basin-wide surge in autumn 2012. We used multiple numerical models to explore hydrologic activation mechanisms for the surge behaviour. A continuum ice dynamic model was used to invert basal friction coefficient distributions using the control method and observed surface velocity data between April 2012 and July 2014. This has provided input to a discrete element model capable of simulating individual crevasses, with the aim of finding locations where meltwater entered the glacier during the summer and reached the bed. The possible flow paths of surface meltwater reaching the glacier bed as well as those of meltwater produced at the bed were calculated according to the gradient of the hydraulic potential.The inverted friction coefficients show the unplugging of the stagnant ice front and expansion of low-friction regions before the surge reached its peak velocity in January 2013. Crevasse distribution reflects the basal friction pattern to a high degree. The meltwater reaches the bed through the crevasses located above the margins of the subglacial valley and the basal melt that is generated mainly by frictional heating flows either to the fast-flowing units or potentially accumulates in an overdeepened region. Based on these results, the mechanisms facilitated by basal meltwater production, crevasse opening and the routing of meltwater to the bed are discussed for the surge in Basin 3.

  20. High Altitude Emissions of Black Carbon Aerosols: Potential Climate Implications

    Science.gov (United States)

    Satheesh, S. K.

    2017-12-01

    Synthesizing a series of ground-based and airborne measurements of aerosols over the Indian region during summer and pre-monsoon seasons have revealed the persistence of elevated absorbing aerosol layers over most of the Indian region; more than 50% of which located above clouds. Subsequent, in situ measurements of black carbon (BC) using high-altitude balloons, showed surprising layers with high concentrations in the middle and upper troposphere even at an altitude of 8 to 10 kms. Simultaneous measurements of the vertical thermal structure have shown localized warming due to BC absorption leading to large reduction in lapse rate and sharp temperature inversion, which in turn increases the atmospheric stability. This aerosol-induced stable layer is conducive for maintaining the black carbon layer longer at that level, leading thereby to further solar absorption and subsequently triggering dry convection. These observations support the `solar escalator' concept through which absorption-warming-convection cycles lead to self-lifting of BC to upper troposphere or even to lower stratosphere under favorable conditions in a matter of a few days. Employing an on-line regional chemistry transport model (WRF-Chem), incorporating aircraft emissions, it is shown that emissions from high-flying aircrafts as the most likely source of these elevated black carbon layers. These in-situ injected particles, produce significant warming of the thin air in those heights and lift these layers to even upper tropospheric/lower stratospheric heights, aided by the strong monsoonal convection occurring over the region, which are known to overshoot the tropical tropopause leading to injection of tropospheric air mass (along with its constituent aerosols) into the stratosphere, especially during monsoon season when the tropical tropopause layer is known to be thinnest. These simulations are further supported by the CALIPSO space-borne LIDAR derived extinction coefficient profiles. Based on

  1. Risk Stratification for Athletes and Adventurers in High-Altitude Environments: Recommendations for Preparticipation Evaluation.

    Science.gov (United States)

    Campbell, Aaron D; McIntosh, Scott E; Nyberg, Andy; Powell, Amy P; Schoene, Robert B; Hackett, Peter

    2015-12-01

    High-altitude athletes and adventurers face a number of environmental and medical risks. Clinicians often advise participants or guiding agencies before or during these experiences. Preparticipation evaluation (PPE) has the potential to reduce risk of high-altitude illnesses in athletes and adventurers. Specific conditions susceptible to high-altitude exacerbation also important to evaluate include cardiovascular and lung diseases. Recommendations by which to counsel individuals before participation in altitude sports and adventures are few and of limited focus. We reviewed the literature, collected expert opinion, and augmented principles of a traditional sport PPE to accommodate the high-altitude wilderness athlete/adventurer. We present our findings with specific recommendations on risk stratification during a PPE for the high-altitude athlete/adventurer. Copyright © 2015. Published by Elsevier Inc.

  2. Autophagy Is a Promoter for Aerobic Exercise Performance during High Altitude Training

    Directory of Open Access Journals (Sweden)

    Ying Zhang

    2018-01-01

    Full Text Available High altitude training is one of the effective strategies for improving aerobic exercise performance at sea level via altitude acclimatization, thereby improving oxygen transport and/or utilization. But its underlying molecular mechanisms on physiological functions and exercise performance of athletes are still vague. More recent evidence suggests that the recycling of cellular components by autophagy is an important process of the body involved in the adaptive responses to exercise. Whether high altitude training can activate autophagy or whether high altitude training can improve exercise performance through exercise-induced autophagy is still unclear. In this narrative review article, we will summarize current research advances in the improvement of exercise performance through high altitude training and its reasonable molecular mechanisms associated with autophagy, which will provide a new field to explore the molecular mechanisms of adaptive response to high altitude training.

  3. Research progress on high altitude retinopathy and application of Traditional Chinese Medicine

    Directory of Open Access Journals (Sweden)

    Hai-Xiang Huang

    2014-11-01

    Full Text Available High altitude retinopathy(HARrefers to the body which can't adapt to the hypobaric hypoxia environment at high altitude leading to retinal diseases, which typically manifested as retinal hemorrhages, optic disc edema and cotton wool spots. With the development of high altitude medicine, HAR become a hot topic of eye research in recent years. New researches show a significantly higher incidence of HAR, and HAR has a close contact with acute mountain sickness, high altitude cerebral edema and high altitude pulmonary edema. A further study in pathogenesis and prevention measures of HAR will promote the prevention of altitude sickness. Traditional Chinese Medicine has achieved good effects in the prevention of altitude sickness, but the effect and mechanism of herbs on HAR has not been reported. Through read and summarize the relevant literatures and reports, the author will give an overview of the research advances on HAR's pathogenesis and application of Traditional Chinese Medicine.

  4. Study on Oxygen Supply Standard for Physical Health of Construction Personnel of High-Altitude Tunnels

    Directory of Open Access Journals (Sweden)

    Chun Guo

    2015-12-01

    Full Text Available The low atmospheric pressure and low oxygen content in high-altitude environment have great impacts on the functions of human body. Especially for the personnel engaged in complicated physical labor such as tunnel construction, high altitude can cause a series of adverse physiological reactions, which may result in multiple high-altitude diseases and even death in severe cases. Artificial oxygen supply is required to ensure health and safety of construction personnel in hypoxic environments. However, there are no provisions for oxygen supply standard for tunnel construction personnel in high-altitude areas in current tunnel construction specifications. As a result, this paper has theoretically studied the impacts of high-altitude environment on human bodies, analyzed the relationship between labor intensity and oxygen consumption in high-altitude areas and determined the critical oxygen-supply altitude values for tunnel construction based on two different standard evaluation systems, i.e., variation of air density and equivalent PIO2. In addition, it has finally determined the oxygen supply standard for construction personnel in high-altitude areas based on the relationship between construction labor intensity and oxygen consumption.

  5. Text mining and network analysis to find functional associations of genes in high altitude diseases.

    Science.gov (United States)

    Bhasuran, Balu; Subramanian, Devika; Natarajan, Jeyakumar

    2018-05-02

    Travel to elevations above 2500 m is associated with the risk of developing one or more forms of acute altitude illness such as acute mountain sickness (AMS), high altitude cerebral edema (HACE) or high altitude pulmonary edema (HAPE). Our work aims to identify the functional association of genes involved in high altitude diseases. In this work we identified the gene networks responsible for high altitude diseases by using the principle of gene co-occurrence statistics from literature and network analysis. First, we mined the literature data from PubMed on high-altitude diseases, and extracted the co-occurring gene pairs. Next, based on their co-occurrence frequency, gene pairs were ranked. Finally, a gene association network was created using statistical measures to explore potential relationships. Network analysis results revealed that EPO, ACE, IL6 and TNF are the top five genes that were found to co-occur with 20 or more genes, while the association between EPAS1 and EGLN1 genes is strongly substantiated. The network constructed from this study proposes a large number of genes that work in-toto in high altitude conditions. Overall, the result provides a good reference for further study of the genetic relationships in high altitude diseases. Copyright © 2018 Elsevier Ltd. All rights reserved.

  6. High altitude medicine education in China: exploring a new medical education reform.

    Science.gov (United States)

    Luo, Yongjun; Luo, Rong; Li, Weiming; Huang, Jianjun; Zhou, Qiquan; Gao, Yuqi

    2012-03-01

    China has the largest plateau in the world, which includes the whole of Tibet, part of Qinghai, Xinjiang, Yunnan, and Sichuan. The plateau area is about 257.2×10(4) km(2), which accounts for about 26.8% of the total area of China. According to data collected in 2006, approximately twelve million people were living at high altitudes, between 2200 to 5200 m high, on the Qinghai-Tibetan Plateau. Therefore, there is a need for medical workers who are trained to treat individuals living at high altitudes. To train undergraduates in high altitude medicine, the College of High Altitude Military Medicine was set up at the Third Military Medical University (TMMU) in Chongqing in 1999. This is the only school to teach high altitude medicine in China. Students at TMMU study natural and social sciences, basic medical sciences, clinical medical sciences, and high altitude medicine. In their 5(th) year, students work as interns at the General Hospital of Tibet Military Command in Lhasa for 3 months, where they receive on-site teaching. The method of on-site teaching is an innovative approach for training in high altitude medicine for undergraduates. Three improvements were implemented during the on-site teaching component of the training program: (1) standardization of the learning progress; (2) integration of formal knowledge with clinical experience; and (3) coaching students to develop habits of inquiry and to engage in ongoing self-improvement to set the stage for lifelong learning. Since the establishment of the innovative training methods in 2001, six classes of high altitude medicine undergraduates, who received on-site teaching, have graduated and achieved encouraging results. This evidence shows that on-site teaching needs to be used more widely in high altitude medicine education.

  7. Effect of egg composition and oxidoreductase on adaptation of Tibetan chicken to high altitude.

    Science.gov (United States)

    Jia, C L; He, L J; Li, P C; Liu, H Y; Wei, Z H

    2016-07-01

    Tibetan chickens have good adaptation to hypoxic conditions, which can be reflected by higher hatchability than lowland breeds when incubated at high altitude. The objective of this trial was to study changes in egg composition and metabolism with regards the adaptation of Tibetan chickens to high altitude. We measured the dry weight of chicken embryos, egg yolk, and egg albumen, and the activity of lactate dehydrogenase (LDH) and succinic dehydrogenase (SDH) in breast muscle, heart, and liver from embryos of Tibetan chicken and Dwarf chicken (lowland breed) incubated at high (2,900 m) and low (100 m) altitude. We found that growth of chicken embryos was restricted at high altitude, especially for Dwarf chicken embryos. In Tibetan chicken, the egg weight was lighter, but the dry weight of egg yolk was heavier than that of Dwarf chicken. The LDH activities of the three tissues from the high altitude groups were respectively higher than those of the lowland groups from d 15 to hatching, except for breast muscle of Tibetan chicken embryos on d 15. In addition, under the high altitude environment, the heart tissue from Tibetan chicken had lower LDH activity than that from Dwarf chicken at d 15 and 18. The lactic acid content of blood from Tibetan chicken embryos was lower than that of Dwarf chicken at d 12 and 15 of incubation at high altitude. There was no difference in SDH activity in the three tissues between the high altitude groups and the lowland groups except in three tissues of hatchlings and at d 15 of incubation in breast muscle, nor between the two breeds at high altitude except in the heart of hatchlings. Consequently, the adaptation of Tibetan chicken to high altitude may be associated with higher quantities of yolk in the egg and a low metabolic oxygen demand in tissue, which illuminate the reasons that the Tibetan chicken have higher hatchability with lower oxygen transport ability. © 2016 Poultry Science Association Inc.

  8. Iron supplementation at high altitudes induces inflammation and oxidative injury to lung tissues in rats

    Energy Technology Data Exchange (ETDEWEB)

    Salama, Samir A., E-mail: salama.3@buckeyemail.osu.edu [High Altitude Research Center, Taif University, Al-Haweiah, Taif 21974 (Saudi Arabia); Department of Biochemistry, Faculty of Pharmacy, Al-Azhar University, Cairo 11751 (Egypt); Department of Pharmacology and GTMR Unit, College of Clinical Pharmacy, Taif University, Al-Haweiah, Taif 21974 (Saudi Arabia); Omar, Hany A. [Department of Pharmacology, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514 (Egypt); Maghrabi, Ibrahim A. [Department of Clinical Pharmacy, College of Clinical Pharmacy, Taif University, Al-Haweiah, Taif 21974 (Saudi Arabia); AlSaeed, Mohammed S. [Department of Surgery, College of Medicine, Taif University, Al-Haweiah, Taif 21974 (Saudi Arabia); EL-Tarras, Adel E. [High Altitude Research Center, Taif University, Al-Haweiah, Taif 21974 (Saudi Arabia)

    2014-01-01

    Exposure to high altitudes is associated with hypoxia and increased vulnerability to oxidative stress. Polycythemia (increased number of circulating erythrocytes) develops to compensate the high altitude associated hypoxia. Iron supplementation is, thus, recommended to meet the demand for the physiological polycythemia. Iron is a major player in redox reactions and may exacerbate the high altitudes-associated oxidative stress. The aim of this study was to explore the potential iron-induced oxidative lung tissue injury in rats at high altitudes (6000 ft above the sea level). Iron supplementation (2 mg elemental iron/kg, once daily for 15 days) induced histopathological changes to lung tissues that include severe congestion, dilatation of the blood vessels, emphysema in the air alveoli, and peribronchial inflammatory cell infiltration. The levels of pro-inflammatory cytokines (IL-1β, IL-6, and TNF-α), lipid peroxidation product and protein carbonyl content in lung tissues were significantly elevated. Moreover, the levels of reduced glutathione and total antioxidant capacity were significantly reduced. Co-administration of trolox, a water soluble vitamin E analog (25 mg/kg, once daily for the last 7 days of iron supplementation), alleviated the lung histological impairments, significantly decreased the pro-inflammatory cytokines, and restored the oxidative stress markers. Together, our findings indicate that iron supplementation at high altitudes induces lung tissue injury in rats. This injury could be mediated through excessive production of reactive oxygen species and induction of inflammatory responses. The study highlights the tissue injury induced by iron supplementation at high altitudes and suggests the co-administration of antioxidants such as trolox as protective measures. - Highlights: • Iron supplementation at high altitudes induced lung histological changes in rats. • Iron induced oxidative stress in lung tissues of rats at high altitudes. • Iron

  9. Iron supplementation at high altitudes induces inflammation and oxidative injury to lung tissues in rats

    International Nuclear Information System (INIS)

    Salama, Samir A.; Omar, Hany A.; Maghrabi, Ibrahim A.; AlSaeed, Mohammed S.; EL-Tarras, Adel E.

    2014-01-01

    Exposure to high altitudes is associated with hypoxia and increased vulnerability to oxidative stress. Polycythemia (increased number of circulating erythrocytes) develops to compensate the high altitude associated hypoxia. Iron supplementation is, thus, recommended to meet the demand for the physiological polycythemia. Iron is a major player in redox reactions and may exacerbate the high altitudes-associated oxidative stress. The aim of this study was to explore the potential iron-induced oxidative lung tissue injury in rats at high altitudes (6000 ft above the sea level). Iron supplementation (2 mg elemental iron/kg, once daily for 15 days) induced histopathological changes to lung tissues that include severe congestion, dilatation of the blood vessels, emphysema in the air alveoli, and peribronchial inflammatory cell infiltration. The levels of pro-inflammatory cytokines (IL-1β, IL-6, and TNF-α), lipid peroxidation product and protein carbonyl content in lung tissues were significantly elevated. Moreover, the levels of reduced glutathione and total antioxidant capacity were significantly reduced. Co-administration of trolox, a water soluble vitamin E analog (25 mg/kg, once daily for the last 7 days of iron supplementation), alleviated the lung histological impairments, significantly decreased the pro-inflammatory cytokines, and restored the oxidative stress markers. Together, our findings indicate that iron supplementation at high altitudes induces lung tissue injury in rats. This injury could be mediated through excessive production of reactive oxygen species and induction of inflammatory responses. The study highlights the tissue injury induced by iron supplementation at high altitudes and suggests the co-administration of antioxidants such as trolox as protective measures. - Highlights: • Iron supplementation at high altitudes induced lung histological changes in rats. • Iron induced oxidative stress in lung tissues of rats at high altitudes. • Iron

  10. Outdoor Activity and High Altitude Exposure During Pregnancy: A Survey of 459 Pregnancies.

    Science.gov (United States)

    Keyes, Linda E; Hackett, Peter H; Luks, Andrew M

    2016-06-01

    To evaluate whether women engage in outdoor activities and high altitude travel during pregnancy; the health care advice received regarding high altitude during pregnancy; and the association between high altitude exposure and self-reported pregnancy complications. An online survey of women with at least 1 pregnancy distributed on websites and e-mail lists targeting mothers and/or mountain activities. Outcome measures were outdoor activities during pregnancy, high altitude (>2440 m) exposure during pregnancy, and pregnancy and perinatal complications. Hiking, running, and swimming were the most common activities performed during pregnancy. Women traveled to high altitude in over half of the pregnancies (244/459), and most did not receive counseling regarding altitude (355, 77%), although a small proportion (14, 3%) were told not to go above 2440 m. Rates of miscarriage and most other complications were similar between pregnancies with and without travel above 2440 m. Pregnancies with high altitude exposure were more likely to have preterm labor (odds ratio [OR] 2.3; 95% CI 0.97-5.4; P = .05). Babies born to women who went to high altitude during pregnancy were more likely to need oxygen at birth (OR 2.34; 95% CI 1.04-5.26; P sports and travel to high altitude have a low rate of complications. Given the limitations of our data, further research is necessary on the risks associated with high altitude travel and physical activity and how these apply to the general population. Copyright © 2016 Wilderness Medical Society. Published by Elsevier Inc. All rights reserved.

  11. Hemorrhages and hemostasis in guinea-pigs exposed to irradiation at high altitude

    International Nuclear Information System (INIS)

    Tartakovskij, V.N.; Daniyarov, S.B.

    1988-01-01

    Hemorrhagic intensity, hemostasis and blood vessel wall resistance to mechanical effects were studied in guinea-pigs exposed to whole-body irradiation (3.0 Gy). The animals were irradiated at low altitude (760 m above sea level) and at high altitude (3200 m above sea level) after 1 and 31 days of adaptation. It was demonstrated that hemorrhagic intensity in both groups of guinea-pigs irradiated at high altitude was significantly reduced in comparison with that at low altitude. The decrease of radiation-induced hemorrhages at high altitude is associated with less severe changes in thrombopoiesis, blood vessel wall and blood coagulation

  12. United States high-altitude test experiences. A review emphasizing the impact on the environment

    International Nuclear Information System (INIS)

    Hoerlin, H.

    1976-06-01

    The US high-altitude nuclear explosions of the 1955-1962 period are listed chronologically; dates, locations, and yields are given. The major physical phases of the interactions of the weapon outputs with the atmosphere are described, such as the formation of fireballs at the low high-altitudes and the partition of energies and their distribution over very large spaces at the higher high-altitudes. The effects of these explosions on the normal activities of populations and the protective measures taken are documented. Many scientific observations, together with their significance and values, are reviewed. 109 refs

  13. Chernobyl radioactivity and high altitude air-particulate monitoring at Islamabad

    International Nuclear Information System (INIS)

    Bhatti, M.S.; Ihsanullah; Shafiq, M.; Perveen, N.; Orfi, S.D.

    1987-11-01

    High altitude sampling of air particulates for radioactivity monitoring was conducted at Islamabad after the CHERNOBYL accident. Smears from aeroplanes flying at varying altitudes were collected and analysed for fresh fission products mainly gamma emitters e.g. Ru-103 and Cs-137 etc. The maximum radioactivity observed was of the order of 15Bq/sample for Ru-103 and 9Bq/sample for Cs-137 respectively. The study was purely qualitative in nature indicated the presence of fresh fission radioactivity at high altitudes over Islamabad. For quantitative measurements at high altitudes sophisticated instrumentation/procedure needs to be adopted. (author)

  14. Historical and Future Black Carbon Deposition on the Three Ice Caps: Ice Core Measurements and Model Simulations from 1850 to 2100

    Science.gov (United States)

    Bauer, Susanne E.; Bausch, Alexandra; Nazarenko, Larissa; Tsigaridis, Kostas; Xu, Baiqing; Edwards. Ross; Bisiaux, Marion; McConnell, Joe

    2013-01-01

    Ice core measurements in conjunction with climate model simulations are of tremendous value when examining anthropogenic and natural aerosol loads and their role in past and future climates. Refractory black carbon (BC) records from the Arctic, the Antarctic, and the Himalayas are analyzed using three transient climate simulations performed with the Goddard Institute for Space Studies ModelE. Simulations differ in aerosol schemes (bulk aerosols vs. aerosol microphysics) and ocean couplings (fully coupled vs. prescribed ocean). Regional analyses for past (1850-2005) and future (2005-2100) carbonaceous aerosol simulations focus on the Antarctic, Greenland, and the Himalayas. Measurements from locations in the Antarctic show clean conditions with no detectable trend over the past 150 years. Historical atmospheric deposition of BC and sulfur in Greenland shows strong trends and is primarily influenced by emissions from early twentieth century agricultural and domestic practices. Models fail to reproduce observations of a sharp eightfold BC increase in Greenland at the beginning of the twentieth century that could be due to the only threefold increase in the North American emission inventory. BC deposition in Greenland is about 10 times greater than in Antarctica and 10 times less than in Tibet. The Himalayas show the most complicated transport patterns, due to the complex terrain and dynamical regimes of this region. Projections of future climate based on the four CMIP5 Representative Concentration Pathways indicate further dramatic advances of pollution to the Tibetan Plateau along with decreasing BC deposition fluxes in Greenland and the Antarctic.

  15. Cervical Cap

    Science.gov (United States)

    ... giving birth vaginally, which means the cervical cap may not fit as well. Inconsistent or incorrect use of the cervical cap increases your risk of pregnancy. For example, you may get pregnant when using the cervical cap if: ...

  16. White Mountain Research Station: 25 years of high-altitude research. [organization and functions of test facility for high altitude research

    Science.gov (United States)

    Pace, N.

    1973-01-01

    The organization and functions of a test facility for conducting research projects at high altitudes are discussed. The projects conducted at the facility include the following: (1) bird physiology, (2) cardiorespiratory physiology, (3) endocrinological studies, (4) neurological studies, (5) metabolic studies, and (6) geological studies.

  17. Unmanned Aerial Vehicles: Progress Toward Meeting High Altitude Endurance Aircraft Price Goals

    National Research Council Canada - National Science Library

    1998-01-01

    ...) High Altitude Endurance (HAE) Unmanned Aerial Vehicle (UAV) program to determine whether the average flyaway cost for the Global Hawk and DarkStar HAE alr vehicles will be within DOD's cost goal...

  18. Scientific Approach for Optimising Performance, Health and Safety in High-Altitude Observatories

    Science.gov (United States)

    Böcker, Michael; Vogy, Joachim; Nolle-Gösser, Tanja

    2008-09-01

    The ESO coordinated study “Optimising Performance, Health and Safety in High-Altitude Observatories” is based on a psychological approach using a questionnaire for data collection and assessment of high-altitude effects. During 2007 and 2008, data from 28 staff and visitors involved in APEX and ALMA were collected and analysed and the first results of the study are summarised. While there is a lot of information about biomedical changes at high altitude, relatively few studies have focussed on psychological changes, for example with respect to performance of mental tasks, safety consciousness and emotions. Both, biomedical and psychological changes are relevant factors in occupational safety and health. The results of the questionnaire on safety, health and performance issues demonstrate that the working conditions at high altitude are less detrimental than expected.

  19. Sub-Scale Re-entry Capsule Drop via High Altitude Balloons

    Data.gov (United States)

    National Aeronautics and Space Administration — The project objective is to develop and test a sub-scale version of the Maraia Entry Capsule on a high altitude balloon. The capsule is released at 100,000 ft. The...

  20. Numerical simulation of the ionization effects of low- and high-altitude nuclear explosions

    International Nuclear Information System (INIS)

    Zhao Zhengyu; Wang Xiang

    2007-01-01

    Low-altitude and high-altitude nuclear explosions are sources of intensive additional ionization in ionosphere. In this paper, in terms of the ionization equilibrium equation system and the equation of energy deposition of radiation in atmosphere, and considering the influence of atmosphere, the temporal and spatial distribution of ionization effects caused by atmospheric nuclear detonation are investigated. The calculated results show that the maximum of additional free electron density produced by low-altitude nuclear explosion is greater than that by the high-altitude nuclear burst. As to the influence of instant nuclear radiation, there is obvious difference between the low-altitude and the high-altitude explosions. The influence range and the continuance time caused by delayed nuclear radiation is less for the low-altitude nuclear detonation than that for the high-altitude one. (authors)

  1. SPLENIC INFARCTION: an intriguing and important cause of pain abdomen in high altitude

    Directory of Open Access Journals (Sweden)

    P. K. Hota

    2015-01-01

    Full Text Available Background: Patients with Sickle cell trait (SCT are usually asymptomatic. They are usually unaware of their condition unless they have a family history. There are specific situations, where these people suffer from the effects of sickle cell trait. Splenic syndrome at high altitude is one of the specific problems. It is usually seen after a patient with SCT has been inducted to high altitude like in case of mountaineers and military personnel deployed in high altitude warfare. Pain abdomen due to splenic infarction in individuals with SCT is one of the manifestations. These patients, if diagnosed in time, they can be spared from unnecessary surgical interventions. We present herewith our experience of splenic infarction due to SCT in high altitude and their management.

  2. Science 101: Why Does It Take Longer to Boil Potatoes at High Altitudes?

    Science.gov (United States)

    Robertson, Bill

    2017-01-01

    Why Does It Take Longer to Boil Potatoes at High Altitudes? This column provides background science information for elementary teachers. This month's issue looks at why water boils at different temperatures at different altitudes.

  3. Unchanged cerebral blood flow and oxidative metabolism after acclimatization to high altitude

    DEFF Research Database (Denmark)

    Møller, Kirsten; Paulson, Olaf B; Hornbein, Thomas F.

    2002-01-01

    The authors investigated the effect of acclimatization to high altitude on cerebral blood flow and oxidative metabolism at rest and during exercise. Nine healthy, native sea-level residents were studied 3 weeks after arrival at Chacaltaya, Bolivia (5,260 m) and after reacclimatization to sea level....... At high altitude at rest, arterial carbon dioxide tension, oxygen saturation, and oxygen tension were significantly reduced, and arterial oxygen content was increased because of an increase in hemoglobin concentration. Global cerebral blood flow was similar in the four conditions. Cerebral oxygen delivery...... and cerebral metabolic rates of oxygen and glucose also remained unchanged, whereas cerebral metabolic rates of lactate increased slightly but nonsignificantly at high altitude during exercise compared with high altitude at rest. Reaction time was unchanged. The data indicate that cerebral blood flow...

  4. Adjustment of measurement errors to reconcile precipitation distribution in the high-altitude Indus basin

    NARCIS (Netherlands)

    Dahri, Zakir Hussain; Moors, Eddy; Ludwig, Fulco; Ahmad, Shakil; Khan, Asif; Ali, Irfan; Kabat, Pavel

    2018-01-01

    Precipitation in the high-altitude Indus basin governs its renewable water resources affecting water, energy and food securities. However, reliable estimates of precipitation climatology and associated hydrological implications are seriously constrained by the quality of observed data. As such,

  5. High altitude pulmonary edema. Report of a case with familiar history

    International Nuclear Information System (INIS)

    Velasquez, Jurg Niederbacher; Rueda Manrique, Adriana L; Sanabria Pico, Carmen E

    1998-01-01

    We report the case of a ten years old child, who presented a high altitude pulmonary edema. His father had the same disorder ten years ago. In addition we review the physiopathology, diagnosis and management of this disease

  6. Novel drugs in the management of acute mountain sickness and high altitude pulmonary edema

    OpenAIRE

    Gaurav Sikri, Gaurav; Bhattacharya,Anirban

    2015-01-01

    Gaurav Sikri, Anirban Bhattacharya Department of Physiology, Armed Forces Medical College, Wanowarie, Pune, IndiaWe read with great interest the review article titled “Wilderness medicine at high altitude: recent developments in the field” by Shah et al.1 The authors have comprehensively summarized the recent advances in the field of high altitude medicine relevant to sports and travel medicine. However, Shah et al have described potential drugs for management of high-alti...

  7. Syndrome of Acute Anxiety Among Marines After Recent Arrival at High Altitude

    Science.gov (United States)

    2014-05-01

    Naval Health Research Center Syndrome of Acute Anxiety Among Marines After Recent Arrival at High Altitude Michael K. Sracic Darren Thomas...Allen Pate Jacob Norris Marc Norman, Jeffrey H. Gertsch Report No. 13-29 The views expressed in this article are those of the authors...MEDICINE, 179, 5:559, 2014 Syndrome of Acute Anxiety Among Marines After Recent Arrival at High Altitude LT Michael K. Sracic, MC USN*; LT Darren Thomas

  8. Tests of the Daimler D-IVa Engine at a High Altitude Test Bench

    Science.gov (United States)

    Noack, W G

    1920-01-01

    Reports of tests of a Daimler IVa engine at the test-bench at Friedrichshafen, show that the decrease of power of that engine, at high altitudes, was established, and that the manner of its working when air is supplied at a certain pressure was explained. These tests were preparatory to the installation of compressors in giant aircraft for the purpose of maintaining constant power at high altitudes.

  9. Design study for remotely piloted, high-altitude airplanes powered by microwave energy

    Science.gov (United States)

    Morris, C. E. K., Jr.

    1983-01-01

    A design study has been conducted for unmanned, microwave-powered airplanes that must fly with long endurance at high altitude. They are proposed to conduct communications-relay, observation, or various scientific missions above approximately 55,000 feet altitude. The special characteristics of the microwave-power system and high-altitude, low-speed vehicle are reviewed. Examples of both sizing and performance analysis are used to suggest design procedure guidelines.

  10. Parasympathetic neural activity accounts for the lowering of exercise heart rate at high altitude

    DEFF Research Database (Denmark)

    Boushel, Robert Christopher; Calbet, J A; Rådegran, G

    2001-01-01

    In chronic hypoxia, both heart rate (HR) and cardiac output (Q) are reduced during exercise. The role of parasympathetic neural activity in lowering HR is unresolved, and its influence on Q and oxygen transport at high altitude has never been studied.......In chronic hypoxia, both heart rate (HR) and cardiac output (Q) are reduced during exercise. The role of parasympathetic neural activity in lowering HR is unresolved, and its influence on Q and oxygen transport at high altitude has never been studied....

  11. Experimental StudyHigh Altitude Forced Convective Cooling of Electromechanical Actuation Systems

    Science.gov (United States)

    2016-01-01

    34 Massachusetts Institute of Technology , 1989. [3] FedBizOps.Gov, " Integrated Vehicle Energy Technology (INVENT) Development Program for the 6th...AFRL-RQ-WP-TR-2016-0043 EXPERIMENTAL STUDY—HIGH ALTITUDE FORCED CONVECTIVE COOLING OF ELECTROMECHANICAL ACTUATION SYSTEMS Evan M. Racine...TITLE AND SUBTITLE EXPERIMENTAL STUDY—HIGH ALTITUDE FORCED CONVECTIVE COOLING OF ELECTROMECHANICAL ACTUATION SYSTEMS 5a. CONTRACT NUMBER In-house

  12. Circulation, metabolism, and ventilation during prolonged exposure to carbon monoxide and to high altitude

    Energy Technology Data Exchange (ETDEWEB)

    Klausen, K.; Rasmussen, B; Gjellerod, H.; Madsen, H.; Petersen, E.

    1968-01-01

    Eight volunteers were exposed to CO (13% COHb) or high altitude (3454 m). There was no change in circulation, metabolism, or ventilation during CO exposure. With similar arterial O/sub 2/ concentration from high-altitude, V/sub e/ (BTPS) increased, Pa/sub CO/sub 2// decreased. Regulating mechanisms respond to a decrease in Pa/sub CO/sub 2// rather than a gereral lack in tissue O/sub 2/ per se.

  13. The sleep of elite athletes at sea level and high altitude: a comparison of sea-level natives and high-altitude natives (ISA3600)

    Science.gov (United States)

    Roach, Gregory D; Schmidt, Walter F; Aughey, Robert J; Bourdon, Pitre C; Soria, Rudy; Claros, Jesus C Jimenez; Garvican-Lewis, Laura A; Buchheit, Martin; Simpson, Ben M; Hammond, Kristal; Kley, Marlen; Wachsmuth, Nadine; Gore, Christopher J; Sargent, Charli

    2013-01-01

    Background Altitude exposure causes acute sleep disruption in non-athletes, but little is known about its effects in elite athletes. The aim of this study was to examine the effects of altitude on two groups of elite athletes, that is, sea-level natives and high-altitude natives. Methods Sea-level natives were members of the Australian under-17 soccer team (n=14). High-altitude natives were members of a Bolivian under-20 club team (n=12). Teams participated in an 18-day (19 nights) training camp in Bolivia, with 6 nights at near sea level in Santa Cruz (430 m) and 13 nights at high altitude in La Paz (3600 m). Sleep was assessed on every day/night using activity monitors. Results The Australians’ sleep was shorter, and of poorer quality, on the first night at altitude compared with sea level. Sleep quality returned to normal by the end of the first week at altitude, but sleep quantity had still not stabilised at its normal level after 2 weeks. The quantity and quality of sleep obtained by the Bolivians was similar, or greater, on all nights at altitude compared with sea level. The Australians tended to obtain more sleep than the Bolivians at sea level and altitude, but the quality of the Bolivians’ sleep tended to be better than that of the Australians at altitude. Conclusions Exposure to high altitude causes acute and chronic disruption to the sleep of elite athletes who are sea-level natives, but it does not affect the sleep of elite athletes who are high-altitude natives. PMID:24282197

  14. The sleep of elite athletes at sea level and high altitude: a comparison of sea-level natives and high-altitude natives (ISA3600).

    Science.gov (United States)

    Roach, Gregory D; Schmidt, Walter F; Aughey, Robert J; Bourdon, Pitre C; Soria, Rudy; Claros, Jesus C Jimenez; Garvican-Lewis, Laura A; Buchheit, Martin; Simpson, Ben M; Hammond, Kristal; Kley, Marlen; Wachsmuth, Nadine; Gore, Christopher J; Sargent, Charli

    2013-12-01

    Altitude exposure causes acute sleep disruption in non-athletes, but little is known about its effects in elite athletes. The aim of this study was to examine the effects of altitude on two groups of elite athletes, that is, sea-level natives and high-altitude natives. Sea-level natives were members of the Australian under-17 soccer team (n=14). High-altitude natives were members of a Bolivian under-20 club team (n=12). Teams participated in an 18-day (19 nights) training camp in Bolivia, with 6 nights at near sea level in Santa Cruz (430 m) and 13 nights at high altitude in La Paz (3600 m). Sleep was assessed on every day/night using activity monitors. The Australians' sleep was shorter, and of poorer quality, on the first night at altitude compared with sea level. Sleep quality returned to normal by the end of the first week at altitude, but sleep quantity had still not stabilised at its normal level after 2 weeks. The quantity and quality of sleep obtained by the Bolivians was similar, or greater, on all nights at altitude compared with sea level. The Australians tended to obtain more sleep than the Bolivians at sea level and altitude, but the quality of the Bolivians' sleep tended to be better than that of the Australians at altitude. Exposure to high altitude causes acute and chronic disruption to the sleep of elite athletes who are sea-level natives, but it does not affect the sleep of elite athletes who are high-altitude natives.

  15. Shape memory alloy resistance behaviour at high altitude for feedback control

    Science.gov (United States)

    Ng, W. T.; Sedan, M. F.; Abdullah, E. J.; Azrad, S.; Harithuddin, A. S. M.

    2017-12-01

    Many recent aerospace technologies are using smart actuators to reduce the system's complexity and increase its reliability. One such actuator is shape memory alloy (SMA) actuator, which is lightweight, produces high force and large deflection. However, some disadvantages in using SMA actuators have been identified and they include nonlinear response of the strain to input current, hysteresis characteristic that results in inaccurate control and less than optimum system performance, high operating temperatures, slow response and also high requirement of electrical power to obtain the desired actuation forces. It is still unknown if the SMA actuators can perform effectively at high altitude with low surrounding temperature. The work presented here covers the preliminary process of verifying the feasibility of using resistance as feedback control at high altitude for aerospace applications. Temperature and resistance of SMA actuator at high altitude is investigated by conducting an experiment onboard a high altitude balloon. The results from the high altitude experiment indicate that the resistance or voltage drop of the SMA wire is not significantly affected by the low surrounding temperature at high altitude as compared to the temperature of SMA. Resistance feedback control for SMA actuators may be suitable for aerospace applications.

  16. Novel drugs in the management of acute mountain sickness and high altitude pulmonary edema

    Directory of Open Access Journals (Sweden)

    Sikri G

    2015-12-01

    Full Text Available Gaurav Sikri, Anirban Bhattacharya Department of Physiology, Armed Forces Medical College, Wanowarie, Pune, IndiaWe read with great interest the review article titled “Wilderness medicine at high altitude: recent developments in the field” by Shah et al.1 The authors have comprehensively summarized the recent advances in the field of high altitude medicine relevant to sports and travel medicine. However, Shah et al have described potential drugs for management of high-altitude illnesses, such as acute mountain sickness (AMS, high altitude cerebral edema, and high altitude pulmonary edema (HAPE as one group under the section “Novel drug treatment for AMS”. The pathophysiologies of these two sets of diseases (AMS/high altitude cerebral edema as one and HAPE as another set are different2 and hence it would have been nice to have had the novel drugs described separately to elucidate the therapeutic approach for the two different classes of diseases.View original paper by Shah et al.

  17. Cognitive Changes during Prolonged Stay at High Altitude and Its Correlation with C-Reactive Protein.

    Directory of Open Access Journals (Sweden)

    Sheng Li Hu

    Full Text Available Hypersensitive C-reaction protein (hsCRP may be a risk factor for cognitive impairment resulting from Alzheimer's disease (AD, stroke, and vascular dementia. This study explored the correlation of peripheral blood hsCRP level with cognitive decline due to high altitude exposure. The study was conducted on 100 male military participants who had never been to high altitude. Cerebral oxygen saturation monitoring, event related potentials (P300, N200 detection, and neurocognitive assessment was performed and total hsCRP, interleukin-6 (IL-6, and homocysteine was estimated at 500 m altitude, 3650 m altitude, 3 day, 1, and 3 month post arriving at the base camp (4400 m, and 1 month after coming back to the 500 m altitude. High altitude increased brain oxygen saturation, prolonged P300 and N200 latencies, injured cognitive functions, and raised plasma hsCRP levels. But they all recovered in varying degrees at 1 and 3 month post arriving at the base camp (4400 m. P300 latencies and hsCRP levels were strongly correlated to cognitive performances. These results suggested that cognitive deterioration occurred during the acute period of exposure to high altitude and may recover probably owning to acclimatization after extended stay at high altitude. Plasma hsCRP is inversely correlated to neurological cognition and it may be a potential biomarker for the prediction of high altitude induced cognitive dysfunction.

  18. Weather Avoidance Guidelines for NASA Global Hawk High-Altitude UAS

    Science.gov (United States)

    Cecil, Daniel J.; Zipser, Edward J.; Velden, Chris; Monette, Sarah; Heymsfield, Gerry; Braun, Scott; Newman, Paul; Black, Pete; Black, Michael; Dunion, Jason

    2014-01-01

    NASA operates two Global Hawk unmanned aircraft systems for Earth Science research projects. In particular, they are used in the Hurricane and Severe Storm Sentinel (HS3) project during 2012, 2013, and 2014 to take measurements from the environment around tropical cyclones, and from directly above tropical cyclones. There is concern that strict adherence to the weather avoidance rules used in 2012 may sacrifice the ability to observe important science targets. We have proposed modifications to these weather avoidance rules that we believe will improve the ability to observe science targets without compromising aircraft safety. The previous guidelines, used in 2012, specified: Do not approach thunderstorms within 25 nm during flight at FL500 or below. When flying above FL500: Do not approach reported lightning within 25NM in areas where cloud tops are reported at FL500 or higher. Aircraft should maintain at least 10000 ft vertical separation from reported lightning if cloud tops are below FL500. No over-flight of cumulus tops higher than FL500. No flight into forecast or reported icing conditions. No flight into forecast or reported moderate or severe turbulence Based on past experience with high-altitude flights over tropical cyclones, we have recommended changing this guidance to: Do not approach thunderstorms within 25 nm during flight at FL500 or below. Aircraft should maintain at least 5000 ft vertical separation from significant convective cloud tops except: a) When cloud tops above FL500: In the event of reported significant lightning activity or indicators of significant overshooting tops, do not approach within 10-25 nm, depending on pilot discretion and advice from Mission Scientist. b) When cloud tops are below FL500, maintain 10000 ft separation from reported significant lightning or indicators of significant overshooting tops. No flight into forecasted or reported icing conditions. No flight into forecasted or reported moderate or severe turbulence The

  19. Localized electron density enhancements in the high-altitude polar ionosphere and their relationships with storm-enhanced density (SED plumes and polar tongues of ionization (TOI

    Directory of Open Access Journals (Sweden)

    Y. Kitanoya

    2011-02-01

    Full Text Available Events of localized electron density increase in the high-altitude (>3000 km polar ionosphere are occasionally identified by the thermal plasma instruments on the Akebono satellite. In this paper, we investigate the vertical density structure in one of such events in detail using simultaneous observations by the Akebono and DMSP F15 satellites, the SuperDARN radars, and a network of ground Global Positioning System (GPS receivers, and the statistical characteristics of a large number (>10 000 of such events using Akebono data over half of an 11-year solar cycle. At Akebono altitude, the parallel drift velocity is remarkably low and the O+ ion composition ratio remarkably high, inside the high plasma-density regions at high altitude. Detailed comparisons between Akebono, DMSP ion velocity and density, and GPS total electron content (TEC data suggest that the localized plasma density increase observed at high altitude on Akebono was likely connected with the polar tongue of ionization (TOI and/or storm enhanced density (SED plume observed in the F-region ionosphere. Together with the SuperDARN plasma convection map these data suggest that the TOI/SED plume penetrated into the polar cap due to anti-sunward convection and the plume existed in the same convection channel as the dense plasma at high altitude; in other words, the two were probably connected to each other by the convecting magnetic field lines. The observed features are consistent with the observed high-density plasma being transported from the mid-latitude ionosphere or plasmasphere and unlikely a part of the polar wind population.

  20. Control of breathing and the circulation in high-altitude mammals and birds.

    Science.gov (United States)

    Ivy, Catherine M; Scott, Graham R

    2015-08-01

    Hypoxia is an unremitting stressor at high altitudes that places a premium on oxygen transport by the respiratory and cardiovascular systems. Phenotypic plasticity and genotypic adaptation at various steps in the O2 cascade could help offset the effects of hypoxia on cellular O2 supply in high-altitude natives. In this review, we will discuss the unique mechanisms by which ventilation, cardiac output, and blood flow are controlled in high-altitude mammals and birds. Acclimatization to high altitudes leads to some changes in respiratory and cardiovascular control that increase O2 transport in hypoxia (e.g., ventilatory acclimatization to hypoxia). However, acclimatization or development in hypoxia can also modify cardiorespiratory control in ways that are maladaptive for O2 transport. Hypoxia responses that arose as short-term solutions to O2 deprivation (e.g., peripheral vasoconstriction) or regional variation in O2 levels in the lungs (i.e., hypoxic pulmonary vasoconstriction) are detrimental at in chronic high-altitude hypoxia. Evolved changes in cardiorespiratory control have arisen in many high-altitude taxa, including increases in effective ventilation, attenuation of hypoxic pulmonary vasoconstriction, and changes in catecholamine sensitivity of the heart and systemic vasculature. Parallel evolution of some of these changes in independent highland lineages supports their adaptive significance. Much less is known about the genomic bases and potential interactive effects of adaptation, acclimatization, developmental plasticity, and trans-generational epigenetic transfer on cardiorespiratory control. Future work to understand these various influences on breathing and circulation in high-altitude natives will help elucidate how complex physiological systems can be pushed to their limits to maintain cellular function in hypoxia. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. Right ventricular morphology and function in chronic obstructive pulmonary disease patients living at high altitude.

    Science.gov (United States)

    Güvenç, Tolga Sinan; Erer, Hatice Betül; Kul, Seref; Perinçek, Gökhan; Ilhan, Sami; Sayar, Nurten; Yıldırım, Binnaz Zeynep; Doğan, Coşkun; Karabağ, Yavuz; Balcı, Bahattin; Eren, Mehmet

    2013-01-01

    Pulmonary vasculature is affected in patients with chronic pulmonary obstructive disease (COPD). As a result of increased pulmonary resistance, right ventricular morphology and function are altered in COPD patients. High altitude and related hypoxia causes pulmonary vasoconstriction, thereby affecting the right ventricle. We aimed to investigate the combined effects of COPD and altitude-related chronic hypoxia on right ventricular morphology and function. Forty COPD patients living at high altitude (1768 m) and 41 COPD patients living at sea level were enrolled in the study. All participants were diagnosed as COPD by a pulmonary diseases specialist depending on symptoms, radiologic findings and pulmonary function test results. Detailed two-dimensional echocardiography was performed by a cardiologist at both study locations. Oxygen saturation and mean pulmonary artery pressure were higher in the high altitude group. Right ventricular end diastolic diameter, end systolic diameter, height and end systolic area were significantly higher in the high altitude group compared to the sea level group. Parameters of systolic function, including tricuspid annular systolic excursion, systolic velocity of tricuspid annulus and right ventricular isovolumic acceleration were similar between groups, while fractional area change was significantly higher in the sea level groups compared to the high altitude group. Indices of diastolic function and myocardial performance index were similar between groups. An increase in mean pulmonary artery pressure and right ventricular dimensions are observed in COPD patients living at high altitude. Despite this increase, systolic and diastolic functions of the right ventricle, as well as global right ventricular performance are similar in COPD patients living at high altitude and sea level. Altitude-related adaptation to chronic hypoxia could explain these findings. Copyright © 2012 Australian and New Zealand Society of Cardiac and Thoracic

  2. Mechanisms of Memory Dysfunction during High Altitude Hypoxia Training in Military Aircrew.

    Science.gov (United States)

    Nation, Daniel A; Bondi, Mark W; Gayles, Ellis; Delis, Dean C

    2017-01-01

    Cognitive dysfunction from high altitude exposure is a major cause of civilian and military air disasters. Pilot training improves recognition of the early symptoms of altitude exposure so that countermeasures may be taken before loss of consciousness. Little is known regarding the nature of cognitive impairments manifesting within this critical window when life-saving measures may still be taken. Prior studies evaluating cognition during high altitude simulation have predominantly focused on measures of reaction time and other basic attention or motor processes. Memory encoding, retention, and retrieval represent critical cognitive functions that may be vulnerable to acute hypoxic/ischemic events and could play a major role in survival of air emergencies, yet these processes have not been studied in the context of high altitude simulation training. In a series of experiments, military aircrew underwent neuropsychological testing before, during, and after brief (15 min) exposure to high altitude simulation (20,000 ft) in a pressure-controlled chamber. Acute exposure to high altitude simulation caused rapid impairment in learning and memory with relative preservation of basic visual and auditory attention. Memory dysfunction was predominantly characterized by deficiencies in memory encoding, as memory for information learned during high altitude exposure did not improve after washout at sea level. Retrieval and retention of memories learned shortly before altitude exposure were also impaired, suggesting further impairment in memory retention. Deficits in memory encoding and retention are rapidly induced upon exposure to high altitude, an effect that could impact life-saving situational awareness and response. (JINS, 2017, 23, 1-10).

  3. Difference in blood microcirculation recovery between normal frostbite and high-altitude frostbite

    Directory of Open Access Journals (Sweden)

    Ming-ke JIAO

    2017-02-01

    Full Text Available Objective To determine the difference in blood microcirculation recovery between normal frostbite and high-altitude frostbite during the wound healing. Methods Twenty four male rats were randomly divided into control group (n=8, normal frostbite group (n=8, and high-altitude group (n=8. The normal frostbite group rats were frozen to produce mid-degree frostbite models by controlling the freezing time with liquid nitrogen penetration equipment. The high-altitude frostbite group rats were acclimated to a hypoxic and low-pressure environment for 1 week, and then the high-altitude frostbite models were constructed by the same way with liquid nitrogen penetration apparatus. On days 3, 7, 11, 15, 19, and 23 after modeling, the recovery situation of blood circulation of each group was observed with contrast ultrasonography by injecting SonoVue micro-bubble into rats' tail. Finally, the micro-bubble concentration (MC was calculated to confirm the blood circulation recovery with software Image Pro. Results At different time points, the wound area of the high-altitude frostbite group was bigger than that of the normal frostbite group, and the MC of control group was always about (27±0.2×109/ml. On day 3, 7, 11, 15, 19, and 23, the MC was significantly lower in the high-altitude frostbite group than in the control group and normal frostbite group (P<0.05. The MC of normal frostbite group was significantly lower than that of the control group on day 3, 7, 11, 15 and 19 (P<0.05. In addition, no obvious difference in MC was found between normal group and control group on the 23th day (P<0.05. Conclusion The blood microcirculation recovery after high-altitude frostbite is significantly slower than the normal frostbite. DOI: 10.11855/j.issn.0577-7402.2017.01.13

  4. Phenotypic plasticity and genetic adaptation to high-altitude hypoxia in vertebrates.

    Science.gov (United States)

    Storz, Jay F; Scott, Graham R; Cheviron, Zachary A

    2010-12-15

    High-altitude environments provide ideal testing grounds for investigations of mechanism and process in physiological adaptation. In vertebrates, much of our understanding of the acclimatization response to high-altitude hypoxia derives from studies of animal species that are native to lowland environments. Such studies can indicate whether phenotypic plasticity will generally facilitate or impede adaptation to high altitude. Here, we review general mechanisms of physiological acclimatization and genetic adaptation to high-altitude hypoxia in birds and mammals. We evaluate whether the acclimatization response to environmental hypoxia can be regarded generally as a mechanism of adaptive phenotypic plasticity, or whether it might sometimes represent a misdirected response that acts as a hindrance to genetic adaptation. In cases in which the acclimatization response to hypoxia is maladaptive, selection will favor an attenuation of the induced phenotypic change. This can result in a form of cryptic adaptive evolution in which phenotypic similarity between high- and low-altitude populations is attributable to directional selection on genetically based trait variation that offsets environmentally induced changes. The blunted erythropoietic and pulmonary vasoconstriction responses to hypoxia in Tibetan humans and numerous high-altitude birds and mammals provide possible examples of this phenomenon. When lowland animals colonize high-altitude environments, adaptive phenotypic plasticity can mitigate the costs of selection, thereby enhancing prospects for population establishment and persistence. By contrast, maladaptive plasticity has the opposite effect. Thus, insights into the acclimatization response of lowland animals to high-altitude hypoxia can provide a basis for predicting how altitudinal range limits might shift in response to climate change.

  5. Following the south polar cap recession as viewed by OMEGA/MEX using automatic detection of H2O and CO2 ices.

    Science.gov (United States)

    Schmidt, F.; Doute, S.; Schmitt, B.

    In order to understand Mars' current climate it is necessary to detect, characterize and monitor CO2 and H2O at the surface (permanent and seasonal icy deposits) and in the atmosphere (vapor and clouds). Here we will focus on the South Seasonal Polar Cap (SSPC) whose recession was previously observed with different techniques : from earth in the visible range with HST [James 1996], or from MGS spacecraft with MOC images [Benson 2005], in the thermal IR range by the TES [Kieffer 2000], in the near infrared by OMEGA/MEX [Langevin submitted]. The time and space evolutions of the SSPC is a major annual climatic signal both at the global and the regional scales. In particular the measurement of the temporal and spatial distributions of CO2 constrains exchange processes between both surface and atmosphere. This exchange may involve preponderant species : H2O, CO2 and dust. In this work we will apply a new detection technique : "wavanglet" in order to follow the recession of the SSPC thanks to OMEGA/MEX observations. This method was especially developed in the goal to classify a huge dataset, such OMEGA ones. We propose to use "wavanglet" as a supervised automatic classification method that identifies spectral features and classifies the image in spectrally homogeneous units. Additionally we will evaluate quantitative detection limits of "wavanglet" based on synthetic dataset simulating OMEGA spectra in typical situation of the SSPC. This detection limit will be discussed in terms of abundance for H2O and CO2 ices in order to improve the interpretation of the classification. Finally we will present the recession of the SSPC using "wavanglet" and we will compare the results with those of earlier investigation. An interpretation of the similarities and disagreements between those maps will be done.

  6. Natural Selection on Genes Related to Cardiovascular Health in High-Altitude Adapted Andeans.

    Science.gov (United States)

    Crawford, Jacob E; Amaru, Ricardo; Song, Jihyun; Julian, Colleen G; Racimo, Fernando; Cheng, Jade Yu; Guo, Xiuqing; Yao, Jie; Ambale-Venkatesh, Bharath; Lima, João A; Rotter, Jerome I; Stehlik, Josef; Moore, Lorna G; Prchal, Josef T; Nielsen, Rasmus

    2017-11-02

    The increase in red blood cell mass (polycythemia) due to the reduced oxygen availability (hypoxia) of residence at high altitude or other conditions is generally thought to be beneficial in terms of increasing tissue oxygen supply. However, the extreme polycythemia and accompanying increased mortality due to heart failure in chronic mountain sickness most likely reduces fitness. Tibetan highlanders have adapted to high altitude, possibly in part via the selection of genetic variants associated with reduced polycythemic response to hypoxia. In contrast, high-altitude-adapted Quechua- and Aymara-speaking inhabitants of the Andean Altiplano are not protected from high-altitude polycythemia in the same way, yet they exhibit other adaptive features for which the genetic underpinnings remain obscure. Here, we used whole-genome sequencing to scan high-altitude Andeans for signals of selection. The genes showing the strongest evidence of selection-including BRINP3, NOS2, and TBX5-are associated with cardiovascular development and function but are not in the response-to-hypoxia pathway. Using association mapping, we demonstrated that the haplotypes under selection are associated with phenotypic variations related to cardiovascular health. We hypothesize that selection in response to hypoxia in Andeans could have vascular effects and could serve to mitigate the deleterious effects of polycythemia rather than reduce polycythemia itself. Copyright © 2017. Published by Elsevier Inc.

  7. Climatic changes at high altitudes from C-14 dating at the discovery site of the Iceman Oetzi

    International Nuclear Information System (INIS)

    Kutschera, W.; Jettmar, B.; Golser, R.; Priller, A.; Puchegger, S.; Steier, P.; Wild, E.M.; Bortenschlager, S.; Oeggl, K.; Rom, W.

    2002-01-01

    An extraordinary archaeological discovery was made in 1991 at a high-altitude mountain pass (Tisenjoch, 3120 m) of the Oetztal Alps near the Austrian-Italian Border. Two mountain hikers accidentally found the body of a man sticking half-way out from a shallow ice-filled depression. Unusual climatic conditions had partly freed the body from his icy grave, where he apparently had rested for thousands of years. Radiocarbon dating of bone and tissue of the Iceman 'Oetzi' - as he was quickly nicknamed - revealed that he had lived some 5200 years ago. This established Oetzi as the oldest well-preserved body from the Neolithic period. In addition to the body, a variety of equipment was found at the site, most of it dating to the same time period. A collection of this and other measurements with emphasis on the environment of the Iceman can be found in. The Iceman story with emphasis on 14 C dating is summarized in. Recently, we dated a variety of materials found at the discovery site of the Iceman with 14 C AMS at the Vienna Environmental Research Accelerator (VERA). Among these materials there are plant remains which grow at high altitudes when the conditions are favorable. They thus serve as sensitive indicators of climatic conditions. The 14 C dates cover a time range from approximately 6000 to 4000 years ago, and give first hints on how the climatic conditions may have changed at the Iceman discovery site during this period of time. Combining this with materials found at the site which must have been brought there by animals and/or humans, the 14 C dates support the general hypothesis that in ancient times people in this region first populated high-altitude areas of the Alps above the timber line, since there they found natural pastures for domesticated animals. It is likely that these first settlers approached the Alps from the south, which also seems to be the direction from which the Iceman came to the Tisenjoch.. In this paper we will summarize our current ideas

  8. Circulatory adaptation to long-term high altitude exposure in Aymaras and Caucasians.

    Science.gov (United States)

    Stuber, Thomas; Scherrer, Urs

    2010-01-01

    About 30 million people live above 2500 m in the Andean Mountains of South America. Among them are 5.5 million Aymaras, an ethnic group with its own language, living on the altiplano of Bolivia, Peru, and northern Chile at altitudes of up to 4400 m. In this high altitude region traces of human population go back for more than 2000 years with constant evolutionary pressure on its residents for genetic adaptation to high altitude. Aymaras as the assumed direct descendents of the ancient cultures living in this region were the focus of much research interest during the last decades and several distinctive adaptation patterns to life at high altitude have been described in this ethnic group. The aim of this article was to review the physiology and pathophysiology of circulatory adaptation and maladaptation to longtime altitude exposure in Aymaras and Caucasians.

  9. Mitochondrial function in human skeletal muscle following high-altitude exposure

    DEFF Research Database (Denmark)

    Jacobs, Robert A; Boushel, Robert; Wright-Paradis, Cynthia

    2013-01-01

    Studies regarding mitochondrial modifications in human skeletal muscle following acclimatization to high altitude are conflicting, and these inconsistencies may be due to the prevalence of representing mitochondrial function through static and isolated measurements of specific mitochondrial...... characteristics. The aim of this study, therefore, was to investigate mitochondrial function in response to high-altitude acclimatization through measurements of respiratory control in the vastus lateralis muscle. Skeletal muscle biopsies were obtained from 10 lowland natives prior to and again after a total of 9......-11 days of exposure to 4559 m. High-resolution respirometry was performed on the muscle samples to compare respiratory chain function and respiratory capacities. Respirometric analysis revealed that mitochondrial function was largely unaffected, because high-altitude exposure did not affect the capacity...

  10. Fatalities in high altitude mountaineering: a review of quantitative risk estimates.

    Science.gov (United States)

    Weinbruch, Stephan; Nordby, Karl-Christian

    2013-12-01

    Quantitative estimates for mortality in high altitude mountaineering are reviewed. Special emphasis is placed on the heterogeneity of the risk estimates and on confounding. Crude estimates for mortality are on the order of 1/1000 to 40/1000 persons above base camp, for both expedition members and high altitude porters. High altitude porters have mostly a lower risk than expedition members (risk ratio for all Nepalese peaks requiring an expedition permit: 0.73; 95 % confidence interval 0.59-0.89). The summit bid is generally the most dangerous part of an expedition for members, whereas most high altitude porters die during route preparation. On 8000 m peaks, the mortality during descent from summit varies between 4/1000 and 134/1000 summiteers (members plus porters). The risk estimates are confounded by human and environmental factors. Information on confounding by gender and age is contradictory and requires further work. There are indications for safety segregation of men and women, with women being more risk averse than men. Citizenship appears to be a significant confounder. Prior high altitude mountaineering experience in Nepal has no protective effect. Commercial expeditions in the Nepalese Himalayas have a lower mortality than traditional expeditions, though after controlling for confounding, the difference is not statistically significant. The overall mortality is increasing with increasing peak altitude for expedition members but not for high altitude porters. In the Nepalese Himalayas and in Alaska, a significant decrease of mortality with calendar year was observed. A few suggestions for further work are made at the end of the article.

  11. Nasal variation in relation to high-altitude adaptations among Tibetans and Andeans.

    Science.gov (United States)

    Butaric, Lauren N; Klocke, Ross P

    2018-05-01

    High-altitude (>2500 m) populations face several pressures, including hypoxia and cold-dry air, resulting in greater respiratory demand to obtain more oxygen and condition inspired air. While cardiovascular and pulmonary adaptations to high-altitude hypoxia have been extensively studied, adaptations of upper-respiratory structures, e.g., nasal cavity, remain untested. This study investigates whether nasal morphology presents adaptations to hypoxic (larger noses) and/or cold-dry (tall/narrow noses) conditions among high-altitude samples. CT scans of two high- and four low-altitude samples from diverse climates were collected (n = 130): high-altitude Tibetans and Peruvians; low-altitude Peruvians, Southern Chinese (temperate), Mongolian-Buriats (cold-dry), and Southeast Asians (hot-wet). Facial and nasal distances were calculated from 3D landmarks placed on digitally-modeled crania. Temperature, precipitation, and barometric pressure data were also obtained. Principal components analysis and analyses of variance primarily indicate size-related differences among the cold-dry (Mongolian-Buriats) and hot-wet (Southeast Asians) adapted groups. Two-block partial least squares (PLS) analysis show weak relationships between size-standardized nasal dimensions and environmental variables. However, among PLS1 (85.90% of covariance), Tibetans display relatively larger nasal cavities related to lower temperatures and barometric pressure; regression analyses also indicate high-altitude Tibetans possess relatively larger internal nasal breadths and heights for their facial size. Overall, nasal differences relate to climate among the cold-dry and hot-wet groups. Specific nasal adaptations were not identified among either Peruvian group, perhaps due to their relatively recent migration history and population structure. However, high-altitude Tibetans seem to exhibit a compromise in nasal morphology, serving in increased oxygen uptake, and air-conditioning processes. © 2018

  12. The effect of chronic erythrocytic polycythemia and high altitude upon plasma and blood volumes.

    Science.gov (United States)

    Burton, R. R.; Smith, A. H.

    1972-01-01

    Comparison of two kinds of physiological chronic erythrocytic polycythemias in order to differentiate the specific effect of erythrocytic polycythemia from the general effects of high altitude upon the plasma volume. The two kinds were produced hormonally in female chickens, at sea level, or by protracted high-altitude exposures. It appears that the vascular system of the body may account for an increase in red blood cell mass either by reduction in plasma volume, or by no change in plasma volume, resulting in differential changes in total blood volumes.

  13. Molecular mechanisms regulating oxygen transport and consumption in high altitude and hibernating mammals

    DEFF Research Database (Denmark)

    Revsbech, Inge Grønvall

    2016-01-01

    The aim of this thesis is to broaden the knowledge of molecular mechanisms of adjustment in oxygen (O2) uptake, conduction, delivery and consumption in mammals adapted to extreme conditions. For this end, I have worked with animals living at high altitude as an example of environmental hypoxia...... of the repeatedly found adaptive traits in animals living at high altitude and in hibernating mammals during hibernation compared with the active state. Factors that affect O2 affinity of Hb include temperature, H+/CO2 via the Bohr effect as well as Cl- and organic phosphates, in mammals mainly 2...

  14. High altitude and hemoglobin function in the vultures Gyps rueppelli and Aegypius monachus

    DEFF Research Database (Denmark)

    Weber, Roy E.; Hiebl, Inge; Braunitzer, Gerhard

    1988-01-01

    Functional characteristics of the stripped composite hemoglobins (Hbs) of lhevultures Gyps rueppellii and Aegypills monachus that can fly at extremely high altitudes, and of component Hbs of G. rueppellii are reported, in relation to influences of pH, temperalure and inositol hexaphosphate. G...... structures of the constituent polypeptide chains to trace molecular adaptations to high-altitude respiration, and to physiological factors (pulmonary hypoxia and hypocapnia, body temperature shifts, and lung and nasal gas and heat exchange) to discern their possible survival value at altitudes of 11300 m....

  15. The use of high altitude remote sensing in determining existing vegetation and monitoring ecological stress

    Science.gov (United States)

    Foster, K.; Garcia, A.

    1972-01-01

    High altitude color and multispectral black and white photography was used to survey existing vegetation and soil conditions on the Empire Ranch where large scale development will soon begin. Utilizing stereo pairs of the high altitude color photography, four vegetation classifications were discernable as a function of topography and foliage characteristics. In contrast to the undeveloped Ranch, the same photography was used to detect environmental changes in the Tucson metropolitan area as a result of rapid urbanization. The most prevalent change related to development is the removal of vegetation in high density areas to allow for housing starts. Erosion then occurs where vegetation has been removed.

  16. A 17-year Record of Meteorological Observations Across the Gran Campo Nevado Ice Cap in Southern Patagonia, Chile, Related to Synoptic Weather Types and Climate Modes

    Directory of Open Access Journals (Sweden)

    Stephanie S. Weidemann

    2018-05-01

    Full Text Available The network of long-term meteorological observations in Southernmost Patagonia is still sparse but crucial to improve our understanding of climatic variability, in particular in the more elevated and partially glaciated Southernmost Andes. Here we present a unique 17-year meteorological record (2000–2016 of four automatic weather stations (AWS across the Gran Campo Nevado Ice Cap (53°S in the Southernmost Andes (Chile and the conventional weather station Jorge Schythe of the Instituto de la Patagonia in Punta Arenas for comparison. We revisit the relationship between in situ observations and large-scale climate models as well as mesoscale weather patterns. For this purpose, a 37-year record of ERA Interim Reanalysis data has been used to compute a weather type classification based on a hierarchical correlation-based leader algorithm. The orographic perturbation on the predominantly westerly airflow determines the hydroclimatic response across the mountain range, leading to significant west-east gradients of precipitation, air temperature and humidity. Annual precipitation sums heavily drop within only tens of kilometers from ~7,500 mm a−1 to less than 800 mm a−1. The occurrence of high precipitation events of up to 620 mm in 5 days and wet spells of up to 61 consecutive days underscore the year-around wet conditions in the Southernmost Andes. Given the strong link between large-scale circulation and orographically controlled precipitation, the synoptic-scale weather conditions largely determine the precipitation and temperature variability on all time scales. Major synoptic weather types with distinct low-pressure cells in the Weddell Sea or Bellingshausen Sea, causing a prevailing southwesterly, northwesterly or westerly airflow, determine the weather conditions in Southernmost Patagonia during 68% of the year. At Gran Campo Nevado, more than 80% of extreme precipitation events occur during the persistence of these weather types. The

  17. Water level changes of high altitude lakes in Himalaya–Karakoram ...

    Indian Academy of Sciences (India)

    2Department of Geology, University of Pune, Pune 411 007, India. 3Chhattisgarh Council of .... influenced by three climate patterns as categorized by precipitation regime: (1) ... Water level changes of high altitude lakes in Himalaya–Karakoram. 1535 ...... mate warming and growth of high elevation inland lakes on the ...

  18. Physiological Changes to the Cardiovascular System at High Altitude and Its Effects on Cardiovascular Disease.

    Science.gov (United States)

    Riley, Callum James; Gavin, Matthew

    2017-06-01

    Riley, Callum James, and Matthew Gavin. Physiological changes to the cardiovascular system at high altitude and its effects on cardiovascular disease. High Alt Med Biol. 18:102-113, 2017.-The physiological changes to the cardiovascular system in response to the high altitude environment are well understood. More recently, we have begun to understand how these changes may affect and cause detriment to cardiovascular disease. In addition to this, the increasing availability of altitude simulation has dramatically improved our understanding of the physiology of high altitude. This has allowed further study on the effect of altitude in those with cardiovascular disease in a safe and controlled environment as well as in healthy individuals. Using a thorough PubMed search, this review aims to integrate recent advances in cardiovascular physiology at altitude with previous understanding, as well as its potential implications on cardiovascular disease. Altogether, it was found that the changes at altitude to cardiovascular physiology are profound enough to have a noteworthy effect on many forms of cardiovascular disease. While often asymptomatic, there is some risk in high altitude exposure for individuals with certain cardiovascular diseases. Although controlled research in patients with cardiovascular disease was largely lacking, meaning firm conclusions cannot be drawn, these risks should be a consideration to both the individual and their physician.

  19. On the High Altitude Platform (HAP W-CDMA System Capacity

    Directory of Open Access Journals (Sweden)

    L. de Haro-Ariet

    2004-06-01

    Full Text Available The performance of a downlink power control model, based on a n-thpower distance law, is evaluated for high altitude platform station(HAPS W-CDMA systems. The downlink capacity using this model iscompared with the uplink capacity. It is shown that the uplink capacityis higher than the downlink capacity.

  20. Metabolic Effects of High Altitude Trekking in Patients With Type 2 Diabetes

    NARCIS (Netherlands)

    de Mol, Pieter; Fokkert, Marion J.; de Vries, Suzanna T.; de Koning, Eelco J. P.; Dikkeschei, Bert D.; Gans, Rijnold O. B.; Tack, Cees J.; Bilo, Henk J. G.

    2012-01-01

    OBJECTIVE-Limited information is available regarding the metabolic effects of high altitude trekking in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS-Thirteen individuals with type 2 diabetes took part, in a 12-day expedition to the summit of Mount Toubkal (altitude, 4,167 m), Morocco,

  1. Metabolic effects of high altitude trekking in patients with type 2 diabetes

    NARCIS (Netherlands)

    Mol, P. de; Fokkert, M.J.; Vries, S.T. de; Koning, E.J. de; Dikkeschei, B.D.; Gans, R.O.; Tack, C.J.J.; Bilo, H.J.

    2012-01-01

    OBJECTIVE Limited information is available regarding the metabolic effects of high altitude trekking in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS Thirteen individuals with type 2 diabetes took part in a 12-day expedition to the summit of Mount Toubkal (altitude, 4,167 m), Morocco,

  2. Oxidative DNA damage and repair in skeletal muscle of humans exposed to high-altitude hypoxia

    International Nuclear Information System (INIS)

    Lundby, Carsten; Pilegaard, Henriette; Hall, Gerrit van; Sander, Mikael; Calbet, Jose; Loft, Steffen; Moeller, Peter

    2003-01-01

    Recent research suggests that high-altitude hypoxia may serve as a model for prolonged oxidative stress in healthy humans. In this study, we investigated the consequences of prolonged high-altitude hypoxia on the basal level of oxidative damage to nuclear DNA in muscle cells, a major oxygen-consuming tissue. Muscle biopsies from seven healthy humans were obtained at sea level and after 2 and 8 weeks of hypoxia at 4100 m.a.s.l. We found increased levels of strand breaks and endonuclease III-sensitive sites after 2 weeks of hypoxia, whereas oxidative DNA damage detected by formamidopyrimidine DNA glycosylase (FPG) protein was unaltered. The expression of 8-oxoguanine DNA glycosylase 1 (OGG1), determined by quantitative RT-PCR of mRNA levels did not significantly change during high-altitude hypoxia, although the data could not exclude a minor upregulation. The expression of heme oxygenase-1 (HO-1) was unaltered by prolonged hypoxia, in accordance with the notion that HO-1 is an acute stress response protein. In conclusion, our data indicate high-altitude hypoxia may serve as a good model for oxidative stress and that antioxidant genes are not upregulated in muscle tissue by prolonged hypoxia despite increased generation of oxidative DNA damage

  3. Cerebral venous system and anatomical predisposition to high-altitude headache

    NARCIS (Netherlands)

    Wilson, Mark H.; Davagnanam, Indran; Holland, Graeme; Dattani, Raj S.; Tamm, Alexander; Hirani, Shashivadan P.; Kolfschoten, Nicky; Strycharczuk, Lisa; Green, Cathy; Thornton, John S.; Wright, Alex; Edsell, Mark; Kitchen, Neil D.; Sharp, David J.; Ham, Timothy E.; Murray, Andrew; Holloway, Cameron J.; Clarke, Kieran; Grocott, Mike P. W.; Montgomery, Hugh; Imray, Chris; Ahuja, V.; Aref-Adib, G.; Burnham, R.; Chisholm, A.; Clarke, K.; Coates, D.; Coates, M.; Cook, D.; Cox, M.; Dhillon, S.; Dougall, C.; Doyle, P.; Duncan, P.; Edsell, M.; Edwards, L.; Evans, L.; Gardiner, P.; Grocott, M.; Gunning, P.; Hart, N.; Harrington, J.; Harvey, J.; Holloway, C.; Howard, D.; Hurlbut, D.; Imray, C.; Ince, C.; Jonas, M.; van der Kaaij, J.

    2013-01-01

    As inspired oxygen availability falls with ascent to altitude, some individuals develop high-altitude headache (HAH). We postulated that HAH results when hypoxia-associated increases in cerebral blood flow occur in the context of restricted venous drainage, and is worsened when cerebral compliance

  4. Air Quality Standards for Particulate Matter (PM) at high altitude cities

    International Nuclear Information System (INIS)

    Bravo Alvarez, H.; Sosa Echeverria, R.; Sanchez Alvarez, P.; Krupa, S.

    2013-01-01

    The Air Quality Standards for Particulate Matter (PM) at high altitude urban areas in different countries, must consider the pressure and temperature due to the effect that these parameters have on the breath volume. This paper shows the importance to correct Air Quality Standards for PM considering pressure and temperature at different altitudes. Specific factors were suggested to convert the information concerning PM, from local to standard conditions, and adjust the Air Quality Standards for different high altitudes cities. The correction factors ranged from: 1.03 for Santiago de Chile to 1.47 for El Alto Bolivia. Other cities in this study include: Mexico City, México; La Paz, Bolivia; Bogota, Cali and Medellin, Colombia; Quito, Ecuador and Cuzco, Peru. If these corrections are not considered, the atmospheric concentrations will be underestimated. - Highlights: ► AQS for particulate matter concentrations adjusted by pressure and temperature. ► Particulate matter concentrations can be underestimated in high altitude Cities. ► Particulate matter concentrations must be compared under the same conditions. - In order to compare high altitude atmospheric PM concentrations with AQS, one must consider T and P of the sampling site.

  5. The Laddermill : Innovative Wind Energy from High Altitudes in Holland and Australia

    NARCIS (Netherlands)

    Lansdorp, B.; Williams, P.

    2006-01-01

    The Laddermill is a novel concept to harvest electricity from high altitude winds. The concept's operating principle is to drive an electric generator using tethered kites. Several kites are deployed to altitudes of more than 1 km by means of a single cable that is connected to a drum on the

  6. Predator-prey interaction reveals local effects of high-altitude insect migration

    Science.gov (United States)

    High-altitude nocturnal insect migrations represent significant pulses of resources, yet are difficult to study and poorly understood. Predator-prey interactions, specifically migratory moth consumption by high-flying bats, potentially reveal flows of migratory insects across a landscape. In North...

  7. Pregnancy at high altitude in the Andes leads to increased total vessel density in healthy newborns

    NARCIS (Netherlands)

    Gassmann, N.N. (Norina N.); H.A. van Elteren (Hugo); T.G. Goos (Tom); Morales, C.R. (Claudia R.); Rivera-Ch, M. (Maria); D.S. Martin; Peralta, P.C. (Patricia Cabala); Del Carpio, A.P. (Agustin Passano); MacHaca, S.A. (Saul Aranibar); Huicho, L. (Luis); I.K.M. Reiss (Irwin); Gassmann, M. (Max); R.C.J. de Jonge (Rogier)

    2016-01-01

    markdownabstractThe developing human fetus is able to cope with the physiological reduction in oxygen supply occurring in utero. However, it is not known if microvascularization of the fetus is augmented when pregnancy occurs at high altitude. Fifty-three healthy term newborns in Puno, Peru (3,840

  8. System for beaming power from earth to a high altitude platform

    Science.gov (United States)

    Friedman, Herbert W.; Porter, Terry J.

    2002-01-01

    Power is transmitted to a high altitude platform by an array of diode pumped solid state lasers each operated at a single range of laser wavelengths outside of infrared and without using adaptive optics. Each laser produces a beam with a desired arrival spot size. An aircraft avoidance system uses a radar system for automatic control of the shutters of the lasers.

  9. Low-resolution ship detection from high-altitude aerial images

    Science.gov (United States)

    Qi, Shengxiang; Wu, Jianmin; Zhou, Qing; Kang, Minyang

    2018-02-01

    Ship detection from optical images taken by high-altitude aircrafts such as unmanned long-endurance airships and unmanned aerial vehicles has broad applications in marine fishery management, ship monitoring and vessel salvage. However, the major challenge is the limited capability of information processing on unmanned high-altitude platforms. Furthermore, in order to guarantee the wide detection range, unmanned aircrafts generally cruise at high altitudes, resulting in imagery with low-resolution targets and strong clutters suffered by heavy clouds. In this paper, we propose a low-resolution ship detection method to extract ships from these high-altitude optical images. Inspired by a recent research on visual saliency detection indicating that small salient signals could be well detected by a gradient enhancement operation combined with Gaussian smoothing, we propose the facet kernel filtering to rapidly suppress cluttered backgrounds and delineate candidate target regions from the sea surface. Then, the principal component analysis (PCA) is used to compute the orientation of the target axis, followed by a simplified histogram of oriented gradient (HOG) descriptor to characterize the ship shape property. Finally, support vector machine (SVM) is applied to discriminate real targets and false alarms. Experimental results show that the proposed method actually has high efficiency in low-resolution ship detection.

  10. High Altitude Remains Associated with Elevated Suicide Rates after Adjusting for Socioeconomic Status: A Study from South Korea

    OpenAIRE

    Kim, Jaelim; Choi, Nari; Lee, Yu-Jin; An, Hyonggin; Kim, Namkug; Yoon, Ho-Kyoung; Lee, Heon-Jeong

    2014-01-01

    There have been several studies supporting a possible relationship between high suicide rate and high altitude. However socioeconomic status may confound this association because low socioeconomic status, which is known to be related to a high suicide rate, is also associated with living at high altitude. This study aims to explore whether the relationship between high altitude and high suicide rate remains after adjusting for socioeconomic status in South Korea. We collected demographic data...

  11. High-altitude adaptation of Tibetan chicken from MT-COI and ATP-6 perspective.

    Science.gov (United States)

    Zhao, Xiaoling; Wu, Nan; Zhu, Qing; Gaur, Uma; Gu, Ting; Li, Diyan

    2016-09-01

    The problem of hypoxia adaptation in high altitudes is an unsolved brainteaser in the field of life sciences. As one of the best chicken breeds with adaptability to highland environment, the Tibetan chicken, is genetically different from lowland chicken breeds. In order to gain a better understanding of the mechanism of hypoxic adaptability in high altitude, in the present study, we focused on the MT-COI together with ATP-6 gene to explore the regulatory mechanisms for hypoxia adaptability in Tibet chicken. Here, we sequenced MT-COI of 29 Tibetan chickens and 30 Chinese domestic chickens and ATP-6 gene of 28 Tibetan chickens and 29 Chinese domestic chickens. In MT-COI gene, 9 single nucleotide polymorphisms (SNPs) were detected though none of these was a missense mutation, confirming the fact that MT-COI gene is a largely conservative sequence. In ATP-6 gene, 6 single nucleotide polymorphisms (SNPs) were detected and we found a missense mutation (m.9441G > A) in the ATP-6 gene of Tibetan chicken resulting in an amino acid substitution. Due to the critical role of ATP-6 gene in the proton translocation and energy metabolism, we speculated the possibility of this mutation playing an important role in easier energy conversion and metabolism in Tibetan chickens than Chinese domestic chickens so as to better adapt to the harsh environment of the high-altitude areas. The Median-joining profile also suggested that haplotype Ha2 has the ancestral position to the other haplotypes and has significant relationship with high-altitude adaptation in ATP-6 gene. Therefore, we considered that the polymorphism (m.9441G > A) in the ATP-6 gene may affect the specific functions of ATP-6 enzyme relating to high-altitude adaptation of Tibetan chicken and MT-COI gene is a largely conservative sequence.

  12. Comparative study of acetazolamide and spironolactone on body fluid compartments on induction to high altitude

    Science.gov (United States)

    Singh, M. V.; Jain, S. C.; Rawal, S. B.; Divekar, H. M.; Parshad, Rajinder; Tyagi, A. K.; Sinha, K. C.

    1986-03-01

    Studies were conducted on 29 male healthy subjects having no previous experience of living at high altitude. These subjects were divided into three groups, i.e., subjects treated with placebo, acetazolamide and spironolactone. These subjects were first studied in Delhi. The drug schedule was started 24 hour prior to the airlift of these subjects to an altitude of 3,500 m and was continued for 48 hour after arrival at high altitude. Total body water, extra cellular water, plasma volume, blood electrolytes, pH, pO2, pCO2 and blood viscosity were determined on 3rd and 12th day of their stay at high altitude. Total body water, extra cellular water intracellular water and plasma volume decreased on high altitude exposure. There was a further slight decrease in these compartments with acetazolamide and spironolactone. It was also observed that spironolactone drives out more water from the extracellular compartment. Loss of plasma water was also confirmed by increased plasma osmolality. Increase in arterial blood pH was noticed on hypoxic exposure but the increase was found less in acetazolamide and spironolactone cases. This decrease in pH is expected to result in better oxygen delivery to the tissues at the low oxygen tension. It was also confirmed because blood pO2 increased in both the groups. No significant change in plasma electrolytes was observed in subjects of various groups. Blood viscosity slightly increased on exposure to high altitude. The degree of rise was found less in the group treated with spironolactone. This study suggests that both the drugs are likely to be beneficial in ameliorating/prevention of AMS syndrome.

  13. The relationship between auroral hiss at high altitudes over the polar caps and the substorm dynamics of aurora

    Czech Academy of Sciences Publication Activity Database

    Titova, E. E.; Yahnin, A. G.; Santolík, Ondřej; Gurnett, D. A.; Jiříček, František; Rauch, J. L.; Lefeuvre, F.; Frank, L. A.; Sigwarth, J. B.; Mogilevsky, M. M.

    2005-01-01

    Roč. 23, - (2005), s. 2117-2128 ISSN 0992-7689 R&D Projects: GA AV ČR IAA3042201; GA ČR GA205/03/0953; GA MŠk ME 650; GA ČR GA202/03/0832; GA MŠk 1P05ME811 Grant - others:ESA PECS(XE) 98025; INTAS(RU) 03-51-4132; NATO(XE) PST.GLG980041; NASA (US) NAG5-7943 Institutional research plan: CEZ:AV0Z30420517 Keywords : Magnetospheric physics (Auroral phenomena, Plasma waves and instabilities, Storms and substorms) Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 1.450, year: 2005

  14. Systems Design and Experimental Evaluation of a High-Altitude Relight Test Facility

    Science.gov (United States)

    Paxton, Brendan

    Novel advances in gas turbine engine combustor technology, led by endeavors into fuel efficiency and demanding environmental regulations, have been fraught with performance and safety concerns. While the majority of low emissions gas turbine engine combustor technology has been necessary for power generation applications, the push for ultra-low NOx combustion in aircraft jet engines has been ever present. Recent state-of-the-art combustor designs notably tackle historic emissions challenges by operating at fuel-lean conditions, which are characterized by an increase in the amount of air flow sent to the primary combustion zone. While beneficial in reducing NOx emissions, the fuel-lean mechanisms that characterize these combustor designs rely heavily upon high-energy and high-velocity air flows to sufficiently mix and atomize fuel droplets, ultimately leading to flame stability concerns during low-power operation. When operating at high-altitude conditions, these issues are further exacerbated by the presence of low ambient air pressures and temperatures, which can lead to engine flame-out situations and hamper engine relight attempts. To aid academic and industrial research ventures into improving the high-altitude lean blow-out and relight performance of modern gas turbine engine combustor technologies, the High-Altitude Relight Test Facility (HARTF) was designed and constructed at the University of Cincinnati (UC) Combustion and Fire Research Laboratory (CFRL). Following its construction, an experimental evaluation of its abilities to facilitate optically-accessible ignition, combustion, and spray testing for gas turbine engine combustor hardware at simulated high-altitude conditions was performed. In its evaluation, performance limit references were established through testing of the HARTF vacuum and cryogenic air-chilling capabilities. These tests were conducted with regard to end-user control---the creation and the maintenance of a realistic high-altitude

  15. Certification and safety aspects relating to the transport of passengers on high altitude balloons in Europe

    Science.gov (United States)

    Schoenmaker, Annelie

    2014-07-01

    High-altitude balloons typically fly between 25 and 50 km in altitude, which, while below the Karman line of 100 km, is yet far above the altitudes typically flown by aircraft. For example, the highest-flying commercial aircraft - the Concorde - had a maximum cruising altitude of only 18 km. zero2infinity, a Spanish company, is currently developing a pressurized pod named “bloon” which will be capable of lifting six people, including two pilot crew members and four paying passengers, to an altitude of 36 km through the use of high-altitude balloons. The boundary between Airspace and Outer Space has never been legally defined, mostly because of the lack of activities taking place between the altitude where airplanes fly and the lowest orbiting spacecraft. High-altitude balloons do fly at these in-between altitudes and the prospect of commercializing access to these parts of the stratosphere poses some questions in a new light. Given the relatively low altitude at which they fly, it may well be that these types of balloons would be considered to operate exclusively within air space. However, given the technology involved in crewed high altitude balloon flights, which is more similar to spacecraft engineering than to traditional hot-air or gas ballooning, it is necessary to evaluate the various legal regimes, codes, and regulations that would apply to such flights, especially regarding licenses and liabilities. For high altitude balloon flights commencing in Europe, the European Aviation Safety Agency (EASA) would very likely be the competent certification or licensing agency for these flights, although there would likely be input from various national aviation authorities as well. However, because the European Commission (EC) has not yet issued regulations regarding commercial spaceflight, particularly the use of high altitude balloons, new rules and regulations governing such flights may still need to be drafted and promulgated. With the development of

  16. High Altitude Balloons as a Platform for Space Radiation Belt Science

    Science.gov (United States)

    Mazzino, L.; Buttenschoen, A.; Farr, Q.; Hodgson, C.; Johnson, W.; Mann, I. R.; Rae, J.; University of Alberta High Altitude Balloons (UA-HAB)

    2011-12-01

    The goals of the University of Alberta High Altitude Balloons Program (UA-HAB) are to i) use low cost balloons to address space radiation science, and ii) to utilise the excitement of "space mission" involvement to promote and facilitate the recruitment of undergraduate and graduate students in physics, engineering, and atmospheric sciences to pursue careers in space science and engineering. The University of Alberta High Altitude Balloons (UA-HAB) is a unique opportunity for University of Alberta students (undergraduate and graduate) to engage in the hands-on design, development, build, test and flight of a payload to operate on a high altitude balloon at around 30km altitude. The program development, including formal design and acceptance tests, reports and reviews, mirror those required in the development of an orbital satellite mission. This enables the students to gain a unique insight into how space missions are flown. UA-HAB is a one and half year program that offers a gateway into a high-altitude balloon mission through hands on experience, and builds skills for students who may be attracted to participate in future space missions in their careers. This early education will provide students with the experience necessary to better assess opportunities for pursuing a career in space science. Balloons offer a low-cost alternative to other suborbital platforms which can be used to address radiation belt science goals. In particular, the participants of this program have written grant proposal to secure funds for this project, have launched several 'weather balloon missions', and have designed, built, tested, and launched their particle detector called "Maple Leaf Particle Detector". This detector was focussed on monitoring cosmic rays and space radiation using shielded Geiger tubes, and was flown as one of the payloads from the institutions participating in the High Altitude Student Platform (HASP), organized by the Louisiana State University and the Louisiana

  17. Mammals of the high altitudes of western Arunachal Pradesh, eastern Himalaya: an assessment of threats and conservation needs

    NARCIS (Netherlands)

    Mishra, C.; Madhusudan, M.D.; Datta, A.

    2006-01-01

    he high altitudes of Arunachal Pradesh, India, located in the Eastern Himalaya biodiversity hotspot, remain zoologically unexplored and unprotected. We report results of recent mammal surveys in the high altitude habitats of western Arunachal Pradesh. A total of 35 mammal species (including 12

  18. Turbojet Performance and Operation at High Altitudes with Hydrogen and Jp-4 Fuels

    Science.gov (United States)

    Fleming, W A; Kaufman, H R; Harp, J L , Jr; Chelko, L J

    1956-01-01

    Two current turbojet engines were operated with gaseous-hydrogen and JP-4 fuels at very high altitudes and a simulated Mach number of 0.8. With gaseous hydrogen as the fuel stable operation was obtained at altitudes up to the facility limit of about 90,000 feet and the specific fuel consumption was only 40 percent of that with JP-4 fuel. With JP-4 as the fuel combustion was unstable at altitudes above 60,000 to 65,000 feet and blowout limits were reached at 75,000 to 80,000 feet. Over-all performance, component efficiencies, and operating range were reduced considerable at very high altitudes with both fuels.

  19. Angiotensin-converting enzyme (ACE) alleles in the Quechua, a high altitude South American native population.

    Science.gov (United States)

    Rupert, J L; Devine, D V; Monsalve, M V; Hochachka, P W

    1999-01-01

    Recently it was reported that an allelic variant of the gene encoding angiotensin-converting enzyme (ACE) was significantly over-represented in a cohort of elite British mountaineers. It was proposed that this may be evidence for a specific genetic factor influencing the human capacity for physical performance. The implication that this allele could enhance performance at high altitude prompted us to determine its frequency in Quechua speaking natives living at altitudes greater than 3000m on the Andean Altiplano in South America. We found that the frequency of the putative performance allele in the Quechuas, although significantly higher than in Caucasians, was not different from lowland Native American populations. This observation suggests that, although the higher frequency of the 'performance allele' may have facilitated the migration of the ancestral Quechua to the highlands, the ACE insertion allele has not been subsequently selected for in this high altitude population.

  20. Comparative Study of Wing Lift Distribution Analysis for High Altitude Long Endurance (HALE) Unmaned Aerial Vehicle

    Science.gov (United States)

    Silitonga, Faber Y.; Agoes Moelyadi, M.

    2018-04-01

    The development of High Altitude Long Endurance (HALE) Unmanned Aerial Vehicle (UAV) has been emerged for both civil and military purposes. Its ability of operating in high altitude with long endurance is important in supporting maritime applications.Preliminary analysis of HALE UAV lift distribution of the wing presented to give decisive consideration for its early development. Ensuring that the generated lift is enough to compensate its own weight. Therotical approach using Pradtl’s non-linear lifting line theory will be compared with modern numerical approach using Computational Fluid Dynamics (CFD). Results of wing lift distribution calculated from both methods will be compared to study the reliability of it. HALE UAV ITB has high aspect ratio wing and will be analyze at cruise flight condition. The result indicates difference between Non-linear Lifting Line and CFD method.

  1. High altitude-induced albuminuria in normal man is enhanced by infusion of low-dose dopamine

    DEFF Research Database (Denmark)

    Hansen, J M; Kanstrup, I L; Richalet, J P

    1996-01-01

    -85) (median with quartiles in parentheses) at high altitude. High altitude hypoxia increased Ualb from 3.2 micrograms min-1 (2.7-3.5) to 5.0 micrograms min-1 (3.3-6.6) (p ... flow (ERPF) from 465 ml min-1 (412-503) to 410 ml min-1 (385-451) (p high altitude. Dopamine...... increased ERPF, GFR, CLi, CNa, and decreased the filtration fraction in both environments. Infusion of dopamine further increased Ualb to 10.5 micrograms min-1 (5.5-64.8) (p high altitude, but had no effect on Ualb at sea level. In conclusion, high altitude hypoxia per se increases the urinary...

  2. Reducing pulmonary injury by hyperbaric oxygen preconditioning during simulated high altitude exposure in rats.

    Science.gov (United States)

    Li, Zhuo; Gao, Chunjin; Wang, Yanxue; Liu, Fujia; Ma, Linlin; Deng, Changlei; Niu, Ko-Chi; Lin, Mao-Tsun; Wang, Chen

    2011-09-01

    Hyperbaric oxygen preconditioning (HBO₂P + HAE) has been found to be beneficial in preventing the occurrence of ischemic damage to brain, spinal cord, heart, and liver in several disease models. In addition, pulmonary inflammation and edema are associated with a marked reduction in the expression levels of both aquaporin (AQP) 1 and AQP5 in the lung. Here, the aims of this study are first to ascertain whether acute lung injury can be induced by simulated high altitude in rats and second to assess whether HBO2P + HAE is able to prevent the occurrence of the proposed high altitude-induced ALI. Rats were randomly divided into the following three groups: the normobaric air (NBA; 21% O₂ at 1 ATA) group, the HBO₂P + high altitude exposure (HAE) group, and the NBA + HAE group. In HBO₂P + HAE group, animals received 100% O₂ at 2.0 ATA for 1 hour per day, for five consecutive days. In HAE groups, animals were exposed to a simulated HAE of 6,000 m in a hypobaric chamber for 24 hours. Right after being taken out to the ambient, animals were anesthetized generally and killed and thoroughly exsanguinated before their lungs were excised en bloc. The lungs were used for both histologic and molecular evaluation and analysis. In NBA + HAE group, the animals displayed higher scores of alveolar edema, neutrophil infiltration, and hemorrhage compared with those of NBA controls. In contrast, the levels of both AQP1 and AQP5 proteins and mRNA expression in the lung in the NBA + HAE group were significantly lower than those of NBA controls. However, the increased lung injury scores and the decreased levels of both AQP1 and AQP5 proteins and mRNA expression in the lung caused by HAE was significantly reduced by HBO₂P + HAE. Our results suggest that high altitude pulmonary injury may be prevented by HBO2P + HAE in rats.

  3. Hyperbaric oxygen preconditioning protects against traumatic brain injury at high altitude.

    Science.gov (United States)

    Hu, S L; Hu, R; Li, F; Liu, Z; Xia, Y Z; Cui, G Y; Feng, H

    2008-01-01

    Recent studies have shown that preconditioning with hyperbaric oxygen (HBO) can reduce ischemic and hemorrhagic brain injury. We investigated effects of HBO preconditioning on traumatic brain injury (TBI) at high altitude and examined the role of matrix metalloproteinase-9 (MMP-9) in such protection. Rats were randomly divided into 3 groups: HBO preconditioning group (HBOP; n = 13), high-altitude group (HA; n = 13), and high-altitude sham operation group (HASO; n = 13). All groups were subjected to head trauma by weight-drop device, except for HASO group. HBOP rats received 5 sessions of HBO preconditioning (2.5 ATA, 100% oxygen, 1 h daily) and then were kept in hypobaric chamber at 0.6 ATA (to simulate pressure at 4000m altitude) for 3 days before operation. HA rats received control pretreatment (1 ATA, room air, 1 h daily), then followed the same procedures as HBOP group. HASO rats were subjected to skull opening only without brain injury. Twenty-four hours after TBI, 7 rats from each group were examined for neurological function and brain water content; 6 rats from each group were killed for analysis by H&E staining and immunohistochemistry. Neurological outcome in HBOP group (0.71 +/- 0.49) was better than HA group (1.57 +/- 0.53; p < 0.05). Preconditioning with HBO significantly reduced percentage of brain water content (86.24 +/- 0.52 vs. 84.60 +/- 0.37; p < 0.01). Brain morphology and structure seen by light microscopy was diminished in HA group, while fewer pathological injuries occurred in HBOP group. Compared to HA group, pretreatment with HBO significantly reduced the number of MMP-9-positive cells (92.25 +/- 8.85 vs. 74.42 +/- 6.27; p < 0.01). HBO preconditioning attenuates TBI in rats at high altitude. Decline in MMP-9 expression may contribute to HBO preconditioning-induced protection of brain tissue against TBI.

  4. Increasing alpine transit traffic through Switzerland will considerably enhance high altitude alpine pollutant levels

    Energy Technology Data Exchange (ETDEWEB)

    Prevot, A S.H.; Dommen, J; Furger, M; Graber, W K [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

    1999-08-01

    Within the EU-Project VOTALP (Vertical Ozone Transports in the Alps), we have shown that deep alpine valleys like the Mesolcina Valley very efficiently transport air out of the polluted valley up to altitudes between 2000 and near 4000 m asl (above sea level). Pollutants emitted in these valleys are very efficiently transported up to high altitudes. (author) 2 figs., 1 tab., 2 refs.

  5. Pollination biology in a tropical high-altitude grassland in Brazil: Interactions at the community level

    OpenAIRE

    Freitas, L; Sazima, M

    2006-01-01

    Surveys of local assemblages of plants and their pollinators are among the most useful ways to evaluate specialization in pollination and to discuss the patterns of plant-pollinator interactions among ecosystems. The high-altitude grasslands from southeastern Brazil constitute diminutive island-like formations surrounded by montane rainforests. We registered the floral traits of 124 species from the Serra da Bricaina grasslands (about 60% of the animal-pollinated species of this flora), and d...

  6. Radiation exposure and high-altitude flight. NCRP Commentary No. 12

    International Nuclear Information System (INIS)

    1995-01-01

    Enhanced air crew and public radiation exposure while flying at current altitudes and speeds has not been adequately addressed. However, the commercial aircraft industry continues to expand with greater numbers of passengers and more air crews year by year. With the expected expansions in high-altitude flight in the next two decades there will be many more people exposed to higher levels of ionizing radiation than currently. The equivalent dose rates at the higher altitudes are of the order of two to three times those received at current aircraft altitudes, but are not known very well, partly because of limitations in the knowledge of the component radiations, especially the high-energy neutron component. The risks are also more uncertain than for low-LET exposures on the ground because of uncertainty in an average W R to use for high-LET radiations. Exposures of current air crew are presently comparable with the average exposures of other radiation workers on the ground (EPA, 1995). Substantially higher exposures must be expected at high altitudes to air crew (perhaps approaching or possibly exceeding the current limit for workers on the ground). Higher exposures to sensitive groups of the population such as the fetuses carried by pregnant women are of special concern. Therefore, steps must be taken to improve our knowledge base with respect to dose levels and risks at these high altitudes. Following acquisition of this knowledge, modifications in radiation protection practices with respect to air crew and passengers will need to be considered and recommended to assure that adequate radiation protection is provided with respect to high-altitude flight

  7. Agroforestry systems, nutrients in litter and microbial activity in soils cultivated with coffee at high altitude

    Directory of Open Access Journals (Sweden)

    Krystal de Alcantara Notaro

    2014-04-01

    Full Text Available Agroforestry systems are an alternative option for sustainable production management. These systems contain trees that absorb nutrients from deeper layers of the soil and leaf litter that help improve the soil quality of the rough terrain in high altitude areas, which are areas extremely susceptible to environmental degradation. The aim of this study was to characterize the stock and nutrients in litter, soil activity and the population of microorganisms in coffee (Coffea arabica L. plantations under high altitude agroforestry systems in the semi-arid region of the state of Pernambuco, Brazil. Samples were collected from the surface litter together with soil samples taken at two depths (0-10 and 10-20 cm from areas each subject to one of the following four treatments: agroforestry system (AS, native forest (NF, biodynamic system (BS and coffee control (CT.The coffee plantation had been abandoned for nearly 15 years and, although there had been no management or harvesting, still contained productive coffee plants. The accumulation of litter and mean nutrient content of the litter, the soil nutrient content, microbial biomass carbon, total carbon, total nitrogen, C/N ratio, basal respiration, microbial quotient, metabolic quotient and microbial populations (total bacteria, fluorescent bacteria group, total fungi and Trichoderma spp. were all analyzed. The systems thatwere exposed to human intervention (A and BS differed in their chemical attributes and contained higher levels of nutrients when compared to NF and CT. BS for coffee production at high altitude can be used as a sustainable alternative in the high altitude zones of the semi-arid region in Brazil, which is an area that is highly susceptible to environmental degradation.

  8. Measurement of the Lense-Thirring drag on high-altitude, laser-ranged artificial satellites

    International Nuclear Information System (INIS)

    Ciufolini, I.

    1986-01-01

    We describe a new method of measuring the Lense-Thirring relativistic nodal drag using LAGEOS together with another high-altitude, laser-ranged, similar satellite with appropriately chosen orbital parameters. We propose, for this purpose, that a future satellite such as LAGEOS II have an inclination supplementary to that of LAGEOS. The experiment proposed here would provide a method for experimental verification of the general relativistic formulation of Mach's principle and measurement of the gravitomagnetic field

  9. Investigation of junior school student myopia in high-altitude Tibetan areas in Qinghai Province

    OpenAIRE

    Xia Han; Hai-Ling Miao; Dan Huang

    2014-01-01

    AIM: To know the rate of students' myopia in junior school and factors affecting its occurrence in high altitude Tibetan areas in Qinghai, and provide basis for the prevention of myopia. METHODS: Totally 2 209 junior school students were extracted as respondent with stratified cluster sampling method. The gender, age, ethnicity, grade, eye behavior, physical activity and parental visual conditions were collected by self-made questionnaire, and the curvature of the cornea, anterior chamber dep...

  10. Thoracic skeletal morphology and high-altitude hypoxia in Andean prehistory.

    Science.gov (United States)

    Weinstein, Karen J

    2007-09-01

    Living humans from the highland Andes exhibit antero-posteriorly and medio-laterally enlarged chests in response to high-altitude hypoxia. This study hypothesizes that morphological responses to high-altitude hypoxia should also be evident in pre-Contact Andean groups. Thoracic skeletal morphology in four groups of human skeletons (N = 347) are compared: two groups from coastal regions (Ancón, Peru, n = 79 and Arica, Chile, n = 123) and two groups from high altitudes (San Pedro de Atacama, Chile, n = 102 and Machu Picchu and Cuzco, Peru, n = 43). Osteometric variables that represent proportions of chest width and depth include sternal and clavicular lengths and breadths and rib length, curvature, and area. Each variable was measured relative to body size, transformed into logarithmic indices, and compared across sex-specific groups using ANOVA and Tukey multiple comparison tests. Atacama highlanders have the largest sternal and clavicular proportions and ribs with the greatest area and least amount of curvature, features that suggest an antero-posteriorly deep and mediolaterally wide thoracic skeleton. Ancón lowlanders exhibit proportions indicating narrower and shallower chests. Machu Picchu and Cuzco males cluster with the other highland group in rib curvature and area at the superior levels of the thorax, whereas chest proportions in Machu Picchu and Cuzco females resemble those of lowlanders. The variation in Machu Picchu and Cuzco males and females is interpreted as the result of population migrations. The presence of morphological traits indicative of enlarged chests in some highland individuals suggests that high-altitude hypoxia was an environmental stressor shaping the biology of highland Andean groups during the pre-Contact period. (c) 2007 Wiley-Liss, Inc.

  11. Genetic variants in EPAS1 contribute to adaptation to high-altitude hypoxia in Sherpas.

    Directory of Open Access Journals (Sweden)

    Masayuki Hanaoka

    Full Text Available Sherpas comprise a population of Tibetan ancestry in the Himalayan region that is renowned for its mountaineering prowess. The very small amount of available genetic information for Sherpas is insufficient to explain their physiological ability to adapt to high-altitude hypoxia. Recent genetic evidence has indicated that natural selection on the endothelial PAS domain protein 1 (EPAS1 gene was occurred in the Tibetan population during their occupation in the Tibetan Plateau for millennia. Tibetan-specific variations in EPAS1 may regulate the physiological responses to high-altitude hypoxia via a hypoxia-inducible transcription factor pathway. We examined three significant tag single-nucleotide polymorphisms (SNPs, rs13419896, rs4953354, and rs4953388 in the EPAS1 gene in Sherpas, and compared these variants with Tibetan highlanders on the Tibetan Plateau as well as with non-Sherpa lowlanders. We found that Sherpas and Tibetans on the Tibetan Plateau exhibit similar patterns in three EPAS1 significant tag SNPs, but these patterns are the reverse of those in non-Sherpa lowlanders. The three SNPs were in strong linkage in Sherpas, but in weak linkage in non-Sherpas. Importantly, the haplotype structured by the Sherpa-dominant alleles was present in Sherpas but rarely present in non-Sherpas. Surprisingly, the average level of serum erythropoietin in Sherpas at 3440 m was equal to that in non-Sherpas at 1300 m, indicating a resistant response of erythropoietin to high-altitude hypoxia in Sherpas. These observations strongly suggest that EPAS1 is under selection for adaptation to the high-altitude life of Tibetan populations, including Sherpas. Understanding of the mechanism of hypoxia tolerance in Tibetans is expected to provide lights to the therapeutic solutions of some hypoxia-related human diseases, such as cardiovascular disease and cancer.

  12. Numerical research on the thermal performance of high altitude scientific balloons

    International Nuclear Information System (INIS)

    Dai, Qiumin; Xing, Daoming; Fang, Xiande; Zhao, Yingjie

    2017-01-01

    Highlights: • A model is presented to evaluate the IR radiation between translucent surfaces. • Comprehensive ascent and thermal models of balloons are established. • The effect of IR transmissivity on film temperature distribution is unneglectable. • Atmospheric IR radiation is the primary thermal factor of balloons at night. • Solar radiation is the primary thermal factor of balloons during the day. - Abstract: Internal infrared (IR) radiation is an important factor that affects the thermal performance of high altitude balloons. The internal IR radiation is commonly neglected or treated as the IR radiation between opaque gray bodies. In this paper, a mathematical model which considers the IR transmissivity of the film is proposed to estimate the internal IR radiation. Comprehensive ascent and thermal models for high altitude scientific balloons are established. Based on the models, thermal characteristics of a NASA super pressure balloon are simulated. The effects of film IR property on the thermal behaviors of the balloon are discussed in detail. The results are helpful for the design and operation of high altitude scientific balloons.

  13. Exploring the Limits of High Altitude GPS for Future Lunar Missions

    Science.gov (United States)

    Ashman, Benjamin W.; Parker, Joel J. K.; Bauer, Frank H.; Esswein, Michael

    2018-01-01

    An increasing number of spacecraft are relying on the Global Positioning System (GPS) for navigation at altitudes near or above the GPS constellation itself - the region known as the Space Service Volume (SSV). While the formal definition of the SSV ends at geostationary altitude, the practical limit of high-altitude space usage is not known, and recent missions have demonstrated that signal availability is sufficient for operational navigation at altitudes halfway to the moon. This paper presents simulation results based on a high-fidelity model of the GPS constellation, calibrated and validated through comparisons of simulated GPS signal availability and strength with flight data from recent high-altitude missions including the Geostationary Operational Environmental Satellite 16 (GOES-16) and the Magnetospheric Multiscale (MMS) mission. This improved model is applied to the transfer to a lunar near-rectilinear halo orbit (NRHO) of the class being considered for the international Deep Space Gateway concept. The number of GPS signals visible and their received signal strengths are presented as a function of receiver altitude in order to explore the practical upper limit of high-altitude space usage of GPS.

  14. Glucose Homeostasis During Short-term and Prolonged Exposure to High Altitudes

    Science.gov (United States)

    Ader, Marilyn; Bergman, Richard N.

    2015-01-01

    Most of the literature related to high altitude medicine is devoted to the short-term effects of high-altitude exposure on human physiology. However, long-term effects of living at high altitudes may be more important in relation to human disease because more than 400 million people worldwide reside above 1500 m. Interestingly, individuals living at higher altitudes have a lower fasting glycemia and better glucose tolerance compared with those who live near sea level. There is also emerging evidence of the lower prevalence of both obesity and diabetes at higher altitudes. The mechanisms underlying improved glucose control at higher altitudes remain unclear. In this review, we present the most current evidence about glucose homeostasis in residents living above 1500 m and discuss possible mechanisms that could explain the lower fasting glycemia and lower prevalence of obesity and diabetes in this population. Understanding the mechanisms that regulate and maintain the lower fasting glycemia in individuals who live at higher altitudes could lead to new therapeutics for impaired glucose homeostasis. PMID:25675133

  15. Genomic analysis of natural selection and phenotypic variation in high-altitude mongolians.

    Directory of Open Access Journals (Sweden)

    Jinchuan Xing

    Full Text Available Deedu (DU Mongolians, who migrated from the Mongolian steppes to the Qinghai-Tibetan Plateau approximately 500 years ago, are challenged by environmental conditions similar to native Tibetan highlanders. Identification of adaptive genetic factors in this population could provide insight into coordinated physiological responses to this environment. Here we examine genomic and phenotypic variation in this unique population and present the first complete analysis of a Mongolian whole-genome sequence. High-density SNP array data demonstrate that DU Mongolians share genetic ancestry with other Mongolian as well as Tibetan populations, specifically in genomic regions related with adaptation to high altitude. Several selection candidate genes identified in DU Mongolians are shared with other Asian groups (e.g., EDAR, neighboring Tibetan populations (including high-altitude candidates EPAS1, PKLR, and CYP2E1, as well as genes previously hypothesized to be associated with metabolic adaptation (e.g., PPARG. Hemoglobin concentration, a trait associated with high-altitude adaptation in Tibetans, is at an intermediate level in DU Mongolians compared to Tibetans and Han Chinese at comparable altitude. Whole-genome sequence from a DU Mongolian (Tianjiao1 shows that about 2% of the genomic variants, including more than 300 protein-coding changes, are specific to this individual. Our analyses of DU Mongolians and the first Mongolian genome provide valuable insight into genetic adaptation to extreme environments.

  16. Peripheral blood lymphocytes: a model for monitoring physiological adaptation to high altitude.

    Science.gov (United States)

    Mariggiò, Maria A; Falone, Stefano; Morabito, Caterina; Guarnieri, Simone; Mirabilio, Alessandro; Pilla, Raffaele; Bucciarelli, Tonino; Verratti, Vittore; Amicarelli, Fernanda

    2010-01-01

    Depending on the absolute altitude and the duration of exposure, a high altitude environment induces various cellular effects that are strictly related to changes in oxidative balance. In this study, we used in vitro isolated peripheral blood lymphocytes as biosensors to test the effect of hypobaric hypoxia on seven climbers by measuring the functional activity of these cells. Our data revealed that a 21-day exposure to high altitude (5000 m) (1) increased intracellular Ca(2+) concentration, (2) caused a significant decrease in mitochondrial membrane potential, and (3) despite possible transient increases in intracellular levels of reactive oxygen species, did not significantly change the antioxidant and/or oxidative damage-related status in lymphocytes and serum, assessed by measuring Trolox-equivalent antioxidant capacity, glutathione peroxidase activity, vitamin levels, and oxidatively modified proteins and lipids. Overall, these results suggest that high altitude might cause an impairment in adaptive antioxidant responses. This, in turn, could increase the risk of oxidative-stress-induced cellular damage. In addition, this study corroborates the use of peripheral blood lymphocytes as an easily handled model for monitoring adaptive response to environmental challenge.

  17. Maximal exercise and muscle oxygen extraction in acclimatizing lowlanders and high altitude natives

    DEFF Research Database (Denmark)

    Lundby, Carsten; Sander, Mikael; van Hall, Gerrit

    2006-01-01

    , and is the focus of the present study. We have studied six lowlanders during maximal exercise at sea level (SL) and with acute (AH) exposure to 4,100 m altitude, and again after 2 (W2) and 8 weeks (W8) of altitude sojourn, where also eight high altitude native (Nat) Aymaras were studied. Fractional arterial muscle...... O(2) extraction at maximal exercise was 90.0+/-1.0% in the Danish lowlanders at sea level, and remained close to this value in all situations. In contrast to this, fractional arterial O(2) extraction was 83.2+/-2.8% in the high altitude natives, and did not change with the induction of normoxia....... The capillary oxygen conductance of the lower extremity, a measure of oxygen diffusing capacity, was decreased in the Danish lowlanders after 8 weeks of acclimatization, but was still higher than the value obtained from the high altitude natives. The values were (in ml min(-1) mmHg(-1)) 55.2+/-3.7 (SL), 48...

  18. Phenylethanoid glycosides of Pedicularis muscicola Maxim ameliorate high altitude-induced memory impairment.

    Science.gov (United States)

    Zhou, Baozhu; Li, Maoxing; Cao, Xinyuan; Zhang, Quanlong; Liu, Yantong; Ma, Qiang; Qiu, Yan; Luan, Fei; Wang, Xianmin

    2016-04-01

    Exposure to hypobaric hypoxia causes oxidative stress, neuronal degeneration and apoptosis that leads to memory impairment. Though oxidative stress contributes to neuronal degeneration and apoptosis in hypobaric hypoxia, the ability for phenylethanoid glycosides of Pedicularis muscicola Maxim (PhGs) to reverse high altitude memory impairment has not been studied. Rats were supplemented with PhGs orally for a week. After the fourth day of drug administration, rats were exposed to a 7500 m altitude simulation in a specially designed animal decompression chamber for 3 days. Spatial memory was assessed by the 8-arm radial maze test before and after exposure to hypobaric hypoxia. Histological assessment of neuronal degeneration was performed by hematoxylin-eosin (HE) staining. Changes in oxidative stress markers and changes in the expression of the apoptotic marker, caspase-3, were assessed in the hippocampus. Our results demonstrated that after exposure to hypobaric hypoxia, PhGs ameliorated high altitude memory impairment, as shown by the decreased values obtained for reference memory error (RME), working memory error (WME), and total error (TE). Meanwhile, administration of PhGs decreased hippocampal reactive oxygen species levels and consequent lipid peroxidation by elevating reduced glutathione levels and enhancing the free radical scavenging enzyme system. There was also a decrease in the number of pyknotic neurons and a reduction in caspase-3 expression in the hippocampus. These findings suggest that PhGs may be used therapeutically to ameliorate high altitude memory impairment. Copyright © 2016 Elsevier Inc. All rights reserved.

  19. Solar Cell Short Circuit Current Errors and Uncertainties During High Altitude Calibrations

    Science.gov (United States)

    Snyder, David D.

    2012-01-01

    High altitude balloon based facilities can make solar cell calibration measurements above 99.5% of the atmosphere to use for adjusting laboratory solar simulators. While close to on-orbit illumination, the small attenuation to the spectra may result in under measurements of solar cell parameters. Variations of stratospheric weather, may produce flight-to-flight measurement variations. To support the NSCAP effort, this work quantifies some of the effects on solar cell short circuit current (Isc) measurements on triple junction sub-cells. This work looks at several types of high altitude methods, direct high altitude meas urements near 120 kft, and lower stratospheric Langley plots from aircraft. It also looks at Langley extrapolation from altitudes above most of the ozone, for potential small balloon payloads. A convolution of the sub-cell spectral response with the standard solar spectrum modified by several absorption processes is used to determine the relative change from AMO, lscllsc(AMO). Rayleigh scattering, molecular scatterin g from uniformly mixed gases, Ozone, and water vapor, are included in this analysis. A range of atmosph eric pressures are examined, from 0. 05 to 0.25 Atm to cover the range of atmospheric altitudes where solar cell calibrations a reperformed. Generally these errors and uncertainties are less than 0.2%

  20. EFFECT OF HIGH ALTITUDE ON ERECTILE FUNCTION IN OTHERWISE HEALTHY INDIVIDUALS

    Directory of Open Access Journals (Sweden)

    Usama Bin Zubair

    2016-06-01

    Full Text Available Objective: To determine the effect of high altitude on Erectile function in otherwise healthy individuals and associated socio demographic factors. Study Design: Cross sectional descriptive study. Place and Duration of Study: January 2014 to March 2014 at Goma, Siachin. Material and Methods: One hundred & twenty two married male subjects living at an altitude of more than 15000 feet for more than 3 month and less than one year were included in the study. Erectile dysfunction (ED was assessed using International Index of Erectile Function-5 (IIEF-5. Age, education, smoking, monthly income, any drug intake, altitude, duration of stay and weather conditions were correlated independently with ED. Results: Out of 122, 26 (21.3% had no ED, 18 had mild, 28 (14.8% had mild to moderate, 36(29.5% had moderate and 14 (11.5% had severe ED. Advancing age, low monthly income, smoking, high altitude, cold weather and longer duration of stay had significant association with ED (p-value<0.05 while education and use of any drug were not found significantly associated in our study. Conclusion: This study showed a high prevalence of erectile dysfunction among otherwise healthy individuals when exposed to high altitude. Special attention should be paid on individuals with more age, less income and those working or residing at higher altitudes in peak winter season. Smoking and stay for longer durations should also be discouraged.

  1. Analysis of the Hybrid Power System for High-Altitude Unmanned Aircraft

    Directory of Open Access Journals (Sweden)

    Kangwen Sun

    2015-01-01

    Full Text Available The application of single solar array on high-altitude unmanned aircraft will waste energy because of its low conversion efficiency. Furthermore, since its energy utilization is limited, the surface temperature of solar array will rise to 70°C due to the waste solar energy, thus reducing the electrical performance of the solar array. In order to reuse the energy converted into heat by solar array, a hybrid power system is presented in this paper. In the hybrid power system, a new electricity-generating method is adopted to spread the photovoltaic cell on the wing surface and arrange photothermal power in the wing box section. Because the temperature on the back of photovoltaic cell is high, it can be used as the high-temperature heat source. The lower wing surface can be a low-temperature cold source. A high-altitude unmanned aircraft was used to analyze the performances of pure solar-powered aircraft and hybrid powered aircraft. The analysis result showed that the hybrid system could reduce the area of wing by 19% and that high-altitude unmanned aircraft with a 35 m or less wingspan could raise the utilization rate of solar energy per unit area after adopting the hybrid power system.

  2. Effects of erythrocyte infusion on VO2max at high altitude

    DEFF Research Database (Denmark)

    Young, Jette Feveile; Sawka, M N; Muza, S R

    1996-01-01

    This study investigated whether autologous erythrocyte infusion would ameliorate the decrement in maximal O2 uptake (VO2max) experienced by lowlanders when they ascend to high altitude. VO2max was measured in 16 men (treadmill running) at sea level (SL) and on the 1st (HA1) and 9th (HA9) days...... of high-altitude (4,300 m) residence. After VO2max was measured at SL, subjects were divided into two matched groups (n = 8). Twenty-four hours before ascent to high altitude, the experimental group received a 700-ml infusion of autologous erythrocytes and saline (42% hematocrit), whereas the control...... group received only saline. The VO2max of erythrocyte-infused [54 +/- 1 (SE) ml.kg-1.min-1] and control subjects (52 +/- 2 ml.kg-1.min-1) did not differ at SL before infusion. The decrement in VO2max on HA1 did not differ between groups, averaging 26% overall, despite higher (P

  3. Seasonal variations in the sources of natural and anthropogenic lead deposited at the East Rongbuk Glacier in the high-altitude Himalayas.

    Science.gov (United States)

    Burn-Nunes, Laurie; Vallelonga, Paul; Lee, Khanghyun; Hong, Sungmin; Burton, Graeme; Hou, Shugui; Moy, Andrew; Edwards, Ross; Loss, Robert; Rosman, Kevin

    2014-07-15

    Lead (Pb) isotopic compositions and concentrations, and barium (Ba) and indium (In) concentrations have been analysed at sub-annual resolution in three sections from a snow pit samples dated to 2004/2005, recovered from the East Rongbuk Glacier in the high-altitude Himalayas. Ice core sections indicate that atmospheric chemistry prior to ~1,953 was controlled by mineral dust inputs, with no discernible volcanic or anthropogenic contributions. Eighteenth century monsoon ice core chemistry is indicative of dominant contributions from local Himalayan sources; non-monsoon ice core chemistry is linked to contributions from local (Himalayan), regional (Indian/Thar Desert) and long-range (North Africa, Central Asia) sources. Twentieth century monsoon and non-monsoon ice core data demonstrate similar seasonal sources of mineral dust, however with a transition to less-radiogenic isotopic signatures that suggests local and regional climate/environmental change. The snow pit record demonstrates natural and anthropogenic contributions during both seasons, with increased anthropogenic influence during non-monsoon times. Monsoon anthropogenic inputs are most likely sourced to South/South-East Asia and/or India, whereas non-monsoon anthropogenic inputs are most likely sourced to India and Central Asia. Copyright © 2014 Elsevier B.V. All rights reserved.

  4. High altitude environmental monitoring: the SHARE project and CEOP-HE

    Science.gov (United States)

    Tartari, G.

    2009-04-01

    Mountain areas above 2,500 m a.s.l. constitute about 25% of the Earth's surface and play a fundamental role in the global water balance, while influencing global climate and atmospheric circulation systems. Several millions, including lowlanders, are directly affected by the impacts of climate change on glaciers and water resource distribution. Mountains and high altitude plateaus are subject to the highest rate of temperature increase (e.g., Tibetan Plateau) and are recognized as particularly vulnerable to the effects of climate change. In spite of this, the number of permanent monitoring sites in the major environmental networks decreases with altitude. On a sample of two hundred high altitude automatic weather stations located above 2,500 m a.s.l., less than 20% are over 4,000 m, while there are only 24 stations in the world that could be considered "complete" high altitude observatories. Furthermore, entire mountain areas are left uncovered, creating significant data gaps which make reliable modelling and forecasting nearly impossible. In response to these problems, Ev-K2-CNR has developed the project SHARE (Stations at High Altitude for Research on the Environment) with the support of the Italian government and in collaboration with UNEP. This integrated environmental monitoring and research project aims to improve knowledge on the local, regional and global consequences of climate change in mountain regions and on the influence of high elevations on climate, atmospheric circulation and hydrology. SHARE today boasts a network of 13 permanent monitoring stations between 2,165 m and 8,000 m. Affiliated researchers have produced over 150 scientific publications in atmospheric sciences, meteorology and climate, glaciology, limnology and paleolimnology and geophysics. SHARE network data is also contributed to international programs (UNEP-ABC, WMO-GAW, WCRP-GEWEX-CEOP, NASA-AERONET, ILTER, EU-EUSAAR, EU-ACCENT). Within this context, the CEOP-High Elevations (CEOP

  5. Seasonal variations in the sources of natural and anthropogenic lead deposited at the East Rongbuk Glacier in the high-altitude Himalayas

    International Nuclear Information System (INIS)

    Burn-Nunes, Laurie; Vallelonga, Paul; Lee, Khanghyun; Hong, Sungmin; Burton, Graeme; Hou, Shugui; Moy, Andrew; Edwards, Ross; Loss, Robert; Rosman, Kevin

    2014-01-01

    Lead (Pb) isotopic compositions and concentrations, and barium (Ba) and indium (In) concentrations have been analysed at sub-annual resolution in three sections from a < 110 m ice core dated to the 18th and 20th centuries, as well as snow pit samples dated to 2004/2005, recovered from the East Rongbuk Glacier in the high-altitude Himalayas. Ice core sections indicate that atmospheric chemistry prior to ∼ 1953 was controlled by mineral dust inputs, with no discernible volcanic or anthropogenic contributions. Eighteenth century monsoon ice core chemistry is indicative of dominant contributions from local Himalayan sources; non-monsoon ice core chemistry is linked to contributions from local (Himalayan), regional (Indian/Thar Desert) and long-range (North Africa, Central Asia) sources. Twentieth century monsoon and non-monsoon ice core data demonstrate similar seasonal sources of mineral dust, however with a transition to less-radiogenic isotopic signatures that suggests local and regional climate/environmental change. The snow pit record demonstrates natural and anthropogenic contributions during both seasons, with increased anthropogenic influence during non-monsoon times. Monsoon anthropogenic inputs are most likely sourced to South/South-East Asia and/or India, whereas non-monsoon anthropogenic inputs are most likely sourced to India and Central Asia. - Highlights: • Pb isotopes in ice and snow show seasonality in Mt Everest atmospheric chemistry. • Local (Himalayan) mineral dust inputs are present year round. • Regional and long-range mineral dust inputs are evident during non-monsoon times. • Snow samples indicate increased anthropogenic inputs during non-monsoon times. • Anthropogenic inputs are linked with Indian, South Asian and Central Asian sources

  6. Seasonal variations in the sources of natural and anthropogenic lead deposited at the East Rongbuk Glacier in the high-altitude Himalayas

    Energy Technology Data Exchange (ETDEWEB)

    Burn-Nunes, Laurie, E-mail: L.Nunes@curtin.edu.au [Department of Imaging and Applied Physics, Curtin University, GPO Box U 1987, Perth 6845, Western Australia (Australia); Vallelonga, Paul [Centre for Ice and Climate, Niels Bohr Institute, University of Copenhagen, Juliane Maries Vej 30, DK-2100 Copenhagen Ø (Denmark); Lee, Khanghyun [Environmental Measurement and Analysis Center, National Institute of Environmental Research, Environmental Research Complex, Kyungseo-dong, Seo-gu, Incheon 404-170 (Korea, Republic of); Hong, Sungmin [Department of Ocean Sciences, Inha University, 100 Inha-ro, Nam-gu, Incheon 402-751 (Korea, Republic of); Burton, Graeme [Department of Imaging and Applied Physics, Curtin University, GPO Box U 1987, Perth 6845, Western Australia (Australia); Hou, Shugui [Key Laboratory of Coast and Island development of Ministry of Education, School of Geographic and Oceanographic Sciences, Nanjing University, Nanjing 210093 (China); Moy, Andrew [Department of the Environment, Australian Antarctic Division, Channel Highway, Kingston 7050, Tasmania (Australia); Antarctic Climate and Ecosystems Cooperative Research Centre, University of Tasmania, Private Bag 80, Hobart 7001, Tasmania (Australia); Edwards, Ross; Loss, Robert; Rosman, Kevin [Department of Imaging and Applied Physics, Curtin University, GPO Box U 1987, Perth 6845, Western Australia (Australia)

    2014-07-01

    Lead (Pb) isotopic compositions and concentrations, and barium (Ba) and indium (In) concentrations have been analysed at sub-annual resolution in three sections from a < 110 m ice core dated to the 18th and 20th centuries, as well as snow pit samples dated to 2004/2005, recovered from the East Rongbuk Glacier in the high-altitude Himalayas. Ice core sections indicate that atmospheric chemistry prior to ∼ 1953 was controlled by mineral dust inputs, with no discernible volcanic or anthropogenic contributions. Eighteenth century monsoon ice core chemistry is indicative of dominant contributions from local Himalayan sources; non-monsoon ice core chemistry is linked to contributions from local (Himalayan), regional (Indian/Thar Desert) and long-range (North Africa, Central Asia) sources. Twentieth century monsoon and non-monsoon ice core data demonstrate similar seasonal sources of mineral dust, however with a transition to less-radiogenic isotopic signatures that suggests local and regional climate/environmental change. The snow pit record demonstrates natural and anthropogenic contributions during both seasons, with increased anthropogenic influence during non-monsoon times. Monsoon anthropogenic inputs are most likely sourced to South/South-East Asia and/or India, whereas non-monsoon anthropogenic inputs are most likely sourced to India and Central Asia. - Highlights: • Pb isotopes in ice and snow show seasonality in Mt Everest atmospheric chemistry. • Local (Himalayan) mineral dust inputs are present year round. • Regional and long-range mineral dust inputs are evident during non-monsoon times. • Snow samples indicate increased anthropogenic inputs during non-monsoon times. • Anthropogenic inputs are linked with Indian, South Asian and Central Asian sources.

  7. Protective effects of Astragalus-Lilygranules on intestinal mucosal barrier of mice in high altitude hypoxia

    Directory of Open Access Journals (Sweden)

    Ling LI

    2016-10-01

    Full Text Available Objective  To investigate the protective effect of Astragalus-Lily Granules on intestinal mucosa and intestinal flora homeostasis in mice under high altitude hypoxia condition. Methods  We put mice into high altitude hypoxia cabin to establish high altitude hypoxia model mice. Sixty Kunming mice were randomly divided into control group, model group, Astragalus-Lily particles (ALP low, medium and high dose groups [1.75, 3.5, 7g/(kg•d] respectively. After three days of routine feeding, the ALP mice received drug by intragastric administration, once a day for continuous 17 days,control group and model group were given double distilled water in same volume. From the 15th day, all the mice but control group were exposed to simulated high altitude hypoxia condition for 3 days in a high altitude hypoxia cabin after they were gavaged for half an hour daily. By the 18th day, the fresh mouse feces were collected and smeared to observe the changes of microflora. The pathological changes of intestinal tissues were observed by HE staining and the expression of HIF-1αprotein in intestines was detected by immunohistochemistry. Results  The enterococci and gram negative bacteria showed a higher proportion (65.2%±2.4% and 56.7%±3.3%, respectively in the model group compared with the control group (24.7%±1.2%, 23.2%±1.5%, respectively, P<0.05. The pathological score of intestinal mucosal necrosis and edema (3.10±0.99, 3.30±0.67 respectively and inflammatory cell count (15.93±3.30, 16.40±3.97/ HP respectively was higher compared with the model group (0.70±0.67, 0.80±0.78; 4.07±2.12, 4.28±2.16/HP respectively; P<0.05. HIF-1αexpression increased significantly compared with the model group (P<0.05. The enterococci (46.7%±2.0%, 32.0%±2.6% respectively and gram negative bacteria rate (34.2%±1.6%, 38.0%±2.8% respectively in the ALP medium and high dose groups were lower compared with the model group (24.7%±1.2%, 23.2%±1.5% respectively, P<0

  8. Incidence and care of environmental dermatoses in the high-altitude region of Ladakh, India

    Directory of Open Access Journals (Sweden)

    G K Singh

    2013-01-01

    Full Text Available Background : Low humidity, high-velocity wind, excessive ultraviolet (UV exposure, and extreme cold temperature are the main causes of various types of environmental dermatoses in high altitudes. Materials and Methods: A retrospective study was carried out in patients visiting the lone dermatology department in Ladakh between July 2009 and June 2010. The aim was to identify the common environmental dermatoses in high altitudes so that they can be treated easily or prevented. The patients were divided into three demographic groups, namely, lowlanders, Ladakhis (native highlanders, and tourists. Data was analyzed in a tabulated fashion. Results: A total of 1,567 patients with skin ailments were seen, of whom 965 were lowlanders, 512 native Ladakhis, and 90 were tourists. The skin disorders due to UV rays, dry skin, and papular urticaria were common among all groups. The frequency of melasma ( n = 42; 49.4%, chronic actinic dermatitis (CAD ( n = 18; 81.81% of total CAD cases, and actinic cheilitis ( n = 3; 100% was much higher among the native Ladakhis. The frequency of cold-related injuries was much lesser among Ladakhis ( n = 1; 1.19% than lowlanders ( n = 70; 83.33% and tourists ( n = 13; 15.47% ( P < 0.05. Conclusion: Dryness of skin, tanning, acute or chronic sunburn, polymorphic light reaction, CAD, insect bite reactions, chilblain, and frostbite are common environmental dermatoses of high altitudes. Avoidance of frequent application of soap, application of adequate and suitable emollient, use of effective sunscreen, and wearing of protective clothing are important guidelines for skin care in this region.

  9. Effects of high-altitude exercise training on contractile function of rat skinned cardiomyocyte.

    Science.gov (United States)

    Cazorla, O; Aït Mou, Y; Goret, L; Vassort, G; Dauzat, M; Lacampagne, A; Tanguy, S; Obert, P

    2006-09-01

    Previous studies have questioned whether there is an improved cardiac function after high-altitude training. Accordingly, the present study was designed specifically to test whether this apparent blunted response of the whole heart to training can be accounted for by altered mechanical properties at the cellular level. Adult rats were trained for 5 weeks under normoxic (N, NT for sedentary and trained animals, respectively) or hypobaric hypoxic (H, HT) conditions. Cardiac morphology and function were evaluated by echocardiography. Calcium Ca2+ sensitivity of the contractile machinery was estimated in skinned cardiomyocytes isolated from the left ventricular (LV) sub-epicardium (Epi) and sub-endocardium (Endo) at short and long sarcomere lengths (SL). Cardiac remodelling was harmonious (increase in wall thickness with chamber dilatation) in NT rats and disharmonious (hypertrophy without chamber dilatation) in HT rats. Contrary to NT rats, HT rats did not exhibit enhancement in global cardiac performance evaluated by echocardiography. Stretch- dependent Ca2+ sensitization of the myofilaments (cellular index of the Frank-Starling mechanism) increased from Epi to Endo in N rats. Training in normoxic conditions further increased this stretch-dependent Ca2+ sensitization. Chronic hypoxia did not significantly affect myofibrilar Ca2+ sensitivity. In contrast, high-altitude training decreased Ca2+ sensitivity of the myofilaments at both SL, mostly in Endo cells, resulting in a loss of the transmural gradient of the stretch-dependent Ca2+ sensitization. Expression of myosin heavy chain isoforms was affected both by training and chronic hypoxia but did not correlate with mechanical data. Training at sea level increased the transmural gradient of stretch-dependent Ca2+ sensitization of the myofilaments, accounting for an improved Frank-Starling mechanism. High-altitude training depressed myofilament response to Ca2+, especially in the Endo layer. This led to a reduction in

  10. Rationale and operational plan for a U.S. high-altitude magnetic survey

    Science.gov (United States)

    Hildenbrand, Thomas G.; Acuna, Mario; Bracken, Robert E.; Hardwick, Doug; Hinze, William J.; Keller, Gordon R.; Phillips, Jeff; Roest, Walter

    2002-01-01

    On August 8, 2002, twenty-one scientists from the federal, private and academic sectors met at a workshop in Denver, Co., to discuss the feasibility of collecting magnetic anomaly data on a Canberra aircraft (Figure 1). The need for this 1-day workshop arose because of an exciting and cost-effective opportunity to collect invaluable magnetic anomaly data during a Canberra mission over the U.S. in 2003 and 2004. High Altitude Mapping Missions (HAMM) is currently planning a mission to collect Interferometric Synthetic Aperture Radar (IFSAR) imagery at an altitude of about 15 km and with a flight-line spacing of about 18 km over the conterminous U.S. and Alaska. The additional collection of total and vector magnetic field data would represent a secondary mission objective (i.e., a "piggy-back" magnetometer system). Because HAMM would fund the main flight costs of the mission, the geomagnetic community would obtain invaluable magnetic data at a nominal cost. These unique data would provide new insights on fundamental tectonic and thermal processes and give a new view of the structural and lithologic framework of the crust and possibly the upper mantle. This document highlights: (1) the reasons to conduct this national survey and (2) a preliminary operational plan to collect high-altitude magnetic data of a desired quality and for the expected resources. Although some operational plan issues remain to be resolved, the important conclusions of the workshop are that the Canberra is a very suitable platform to measure the magnetic field and that the planned mission will result in quality high-altitude magnetic data to greatly expand the utility of our national magnetic database.

  11. [Splenic infarction at high altitude, Huaraz-Peru (3,100 masl)].

    Science.gov (United States)

    López de Guimaraes, Douglas; Menacho López, Julio; Villanueva Palacios, Jovita; Mosquera Vásquez, Vitaliano

    2009-01-01

    We report three cases of splenic infarction in healthy men for the first time that amounted to high altitudes, observed in the hospital "Victor Ramos Guardia" Huaraz (3100 m). Case 1 (1995) of 55 years, born in Cuba, from Lima, caucasian suddenly presented acute abdominal pain in epigastrium, distension, nausea and vomiting, was laparotomized for acute abdomen and surgical pathology revealed thrombosis with splenic infarction splenic artery and vein. During follow-up in Lima, hemoglobin electrophoresis showed that it was heterozygous carrier of the sickle trait (Hb A: 57% Hb S: 38.5%). Case 2 (1998) of 23 years, born in Cuba, from Lima, Black said acute abdominal pain in left hypochondrium, shortness of breath and chest pain, clinical examination and radiography of the abdomen showed the spleen volume increased. Case 3 (2006) of 17 years, natural and from Lima, mestizo, who came on tour promotion, acute abdominal pain referred onset in the epigastrium and left hypochondrium, headache, increase heat, nausea and vomiting, pharyngitis was found acute and painful, and spleen increased in size by clinical and x-ray of abdomen simple stand. None had no history of hemoglobinopathy and anemia. In general, medical management was supportive and cases 2 and 3 are recommended hemoglobin electrophoresis. We conclude that we must think of splenic infarction associated with height in any healthy person who is first at high altitude (> 3000m) and having a sudden acute abdominal pain in epigastrium and / or left hypochondrium, pain and palpable spleen and radiological study compatible with image. In this case is indicated by hemoglobin electrophoresis to determine whether there is an individual heterozygous carrier of the sickle trait. splenic infarction, high altitude, sickle trait, Huaraz.

  12. NEURO ENGINEERING TECHNOLOGY TO ACCELERATE THE HUMAN ADAPTATION TO HIGH ALTITUDE HYPOXIA

    Directory of Open Access Journals (Sweden)

    Mukhamed T. Shaov

    2018-01-01

    Full Text Available Abstract. The aim is to study the influence of neuro-information signals modulated by pulse hypoxia on the rhythm of cardiac contractions in low-mountain and high-mountain conditions. Methods. Heart rate was measured using the pulse oxymetry device ELOX-01M2. The impact analysis of information-wave signals was carried out with the help of the neuro-protector "Anthropotherapist", non-invasively (remotely at a distance of up to 5 meters for 5 min. /day during 10 days. The investigations were carried out in lowmountain conditions (city of Nalchik, 550 m above sea level and highlands, Mount Elbrus (site of "Garabashi", 3780 m. above sea level. Participants in the study were divided into groups: control group – 18 participants; experimental group - 18 participants. In the low-mountain and high-mountain conditions, the control group was not affected by the neuro-protector. In high-mountain conditions, the participants in the control group experienced only the effects of high-altitude hypoxia sessions. The experimental group was exposed to the neuro-information signals from the neuro-protector. High-altitude studies were carried out in the following mode: heart rate was recorded at the altitudes of Nalchik - exit to Elbrus – on the way to the site of "Garabashi" - return route to Nalchik. Results. It was found that with frequency exposure, there is a significant decrease and fluctuations in heart rate in low-mountain inhabitants. The stability of these changes in the rhythm of cardiac activity can also be seen in conditions of high-altitude hypoxia. Conclusion. Consequently, the proposed mode of frequency impact, implemented using the "Anthropotherapist" neuro-protector technology, can form a stage of adaptation to hypoxia and unfavorable climatic and environmental factors.

  13. Prototype detector development for measurement of high altitude Martian dust using a future orbiter platform

    Science.gov (United States)

    Pabari, Jayesh; Patel, Darshil; Chokhawala, Vimmi; Bogavelly, Anvesh

    2016-07-01

    Dust devils mostly occur during the mid of Southern hemisphere summer on Mars and play a key role in the background dust opacity. Due to continuous bombardment of micrometeorites, secondary ejecta come out from the Moons of the Mars and can easily escape. This phenomenon can contribute dust around the Moons and therefore, also around the Mars. Similar to the Moons of the Earth, the surfaces of the Martian Moons get charged and cause the dust levitation to occur, adding to the possible dust source. Also, interplanetary dust particles may be able to reach the Mars and contribute further. It is hypothesized that the high altitude Martian dust could be in the form of a ring or tori around the Mars. However, no such rings have been detected to the present day. Typically, width and height of the dust torus is ~5 Mars radii wide (~16950 km) in both the planes as reported in the literature. Recently, very high altitude dust at about 1000 km has been found by MAVEN mission and it is expected that the dust may be concentrated at about 150 to 500 km. However, a langmuir probe cannot explain the source of such dust particles. It is a puzzling question to the space scientist how dust has reached to such high altitudes. A dedicated dust instrument on future Mars orbiter may be helpful to address such issues. To study origin, abundance, distribution and seasonal variation of Martian dust, a Mars Orbit Dust Experiment (MODEX) is proposed. In order to measure the Martian dust from a future orbiter, design of a prototype of an impact ionization dust detector has been initiated at PRL. This paper presents developmental aspects of the prototype dust detector and initial results. The further work is underway.

  14. Factors associated with poor balance ability in older adults of nine high-altitude communities.

    Science.gov (United States)

    Urrunaga-Pastor, Diego; Moncada-Mapelli, Enrique; Runzer-Colmenares, Fernando M; Bailon-Valdez, Zaira; Samper-Ternent, Rafael; Rodriguez-Mañas, Leocadio; Parodi, Jose F

    2018-05-01

    Poor balance ability in older adults result in multiple complications. Poor balance ability has not been studied among older adults living at high altitudes. In this study, we analysed factors associated with poor balance ability by using the Functional Reach (FR) among older adults living in nine high-altitude communities. Analytical cross-sectional study, carried out in inhabitants aged 60 or over from nine high-altitude Andean communities of Peru during 2013-2016. FR was divided according to the cut-off point of 8 inches (20.32 cm) and two groups were generated: poor balance ability (FR less or equal than 20.32 cm) and good balance ability (greater than 20.32 cm). Additionally, we collected socio-demographic, medical, functional and cognitive assessment information. Poisson regression models were constructed to identify factors associated with poor balance ability. Prevalence ratio (PR) with 95% confidence intervals (95CI%) are presented. A total of 365 older adults were studied. The average age was 73.0 ± 6.9 years (range: 60-91 years), and 180 (49.3%) participants had poor balance ability. In the adjusted Poisson regression analysis, the factors associated with poor balance ability were: alcohol consumption (PR = 1.35; 95%CI: 1.05-1.73), exhaustion (PR = 2.22; 95%CI: 1.49-3.31), gait speed (PR = 0.67; 95%CI: 0.50-0.90), having had at least one fall in the last year (PR = 2.03; 95%CI: 1.19-3.46), having at least one comorbidity (PR = 1.60; 95%CI: 1.10-2.35) and having two or more comorbidities (PR = 1.61; 95%CI: 1.07-2.42) compared to none. Approximately a half of the older adults from these high-altitude communities had poor balance ability. Interventions need to be designed to target these balance issues and prevent adverse events from concurring to these individuals. Copyright © 2018 Elsevier B.V. All rights reserved.

  15. The ionization effects from nuclear explosions in high-altitude and their effect to radio propagation

    International Nuclear Information System (INIS)

    Guan Rongsheng; Li Qin

    1997-01-01

    A high-altitude nuclear explosions releases large quantities of energetic particles and electromagnetic radiation capable of producing ionization in the atmosphere. These particles and rays radiation character in the atmosphere are discussed. Ionizations due to explosion X rays, γ rays, neutrons and β particles are considered separately. The time-space distribution of additional electron density is computed and its nature is analyzed. The effects of explosion-induced ionization on the absorption of radio wave is considered and the dependence of the absorption on explosion characteristics, distance from the earth's atmosphere, and frequency of the radio wave is determined

  16. Glucose intolerance associated with hypoxia in people living at high altitudes in the Tibetan highland.

    Science.gov (United States)

    Okumiya, Kiyohito; Sakamoto, Ryota; Ishimoto, Yasuko; Kimura, Yumi; Fukutomi, Eriko; Ishikawa, Motonao; Suwa, Kuniaki; Imai, Hissei; Chen, Wenling; Kato, Emiko; Nakatsuka, Masahiro; Kasahara, Yoriko; Fujisawa, Michiko; Wada, Taizo; Wang, Hongxin; Dai, Qingxiang; Xu, Huining; Qiao, Haisheng; Ge, Ri-Li; Norboo, Tsering; Tsering, Norboo; Kosaka, Yasuyuki; Nose, Mitsuhiro; Yamaguchi, Takayoshi; Tsukihara, Toshihiro; Ando, Kazuo; Inamura, Tetsuya; Takeda, Shinya; Ishine, Masayuki; Otsuka, Kuniaki; Matsubayashi, Kozo

    2016-02-23

    To clarify the association between glucose intolerance and high altitudes (2900-4800 m) in a hypoxic environment in Tibetan highlanders and to verify the hypothesis that high altitude dwelling increases vulnerability to diabetes mellitus (DM) accelerated by lifestyle change or ageing. Cross-sectional epidemiological study on Tibetan highlanders. We enrolled 1258 participants aged 40-87 years. The rural population comprised farmers in Domkhar (altitude 2900-3800 m) and nomads in Haiyan (3000-3100 m), Ryuho (4400 m) and Changthang (4300-4800 m). Urban area participants were from Leh (3300 m) and Jiegu (3700 m). Participants were classified into six glucose tolerance-based groups: DM, intermediate hyperglycaemia (IHG), normoglycaemia (NG), fasting DM, fasting IHG and fasting NG. Prevalence of glucose intolerance was compared in farmers, nomads and urban dwellers. Effects of dwelling at high altitude or hypoxia on glucose intolerance were analysed with the confounding factors of age, sex, obesity, lipids, haemoglobin, hypertension and lifestyle, using multiple logistic regression. The prevalence of DM (fasting DM)/IHG (fasting IHG) was 8.9% (6.5%)/25.1% (12.7%), respectively, in all participants. This prevalence was higher in urban dwellers (9.5% (7.1%)/28.5% (11.7%)) and in farmers (8.5% (6.1%)/28.5% (18.3%)) compared with nomads (8.2% (5.7%)/15.7% (9.7%)) (p=0.0140/0.0001). Dwelling at high altitude was significantly associated with fasting IHG+fasting DM/fasting DM (ORs for >4500 and 3500-4499 m were 3.59/4.36 and 2.07/1.76 vs intolerance. Socioeconomic factors, hypoxaemia and the effects of altitudes >3500 m play a major role in the high prevalence of glucose intolerance in highlanders. Tibetan highlanders may be vulnerable to glucose intolerance, with polycythaemia as a sign of poor hypoxic adaptation, accelerated by lifestyle change and ageing. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please

  17. A Novel Beamforming Technique for Highways Coverage Using High-Altitude Platforms

    Directory of Open Access Journals (Sweden)

    Yasser Albagory

    2007-01-01

    Full Text Available This paper proposes a novel beamforming technique to form an arbitrary-shaped cell for the high-altitude platforms (HAPs mobile communications. The new technique is based on pattern summation of individual low-sidelobe, narrow beams which constitute the desired cell pattern weighted by an amplitude correcting function. The new cell pattern can be adapted to cover the main highways forming worm-shaped cells which may cover the highway for long distances up to 100 km and it will have an important role in reducing frequent handoffs and signaling traffic of location updating from moving users over the long highways.

  18. Augmentation of Quasi-Zenith Satellite Positioning System Using High Altitude Platforms Systems (HAPS)

    Science.gov (United States)

    Tsujii, Toshiaki; Harigae, Masatoshi

    Recently, some feasibility studies on a regional positioning system using the quasi-zenith satellites and the geostationary satellites have been conducted in Japan. However, the geometry of this system seems to be unsatisfactory in terms of the positioning accuracy in north-south direction. In this paper, an augmented satellite positioning system by the High Altitude Platform Systems (HAPS) is proposed since the flexibility of the HAPS location is effective to improve the geometry of satellite positioning system. The improved positioning performance of the augmented system is also demonstrated.

  19. NUCLEOTIDE COMPARISON OF GDF9 GENE IN INDIAN YAK AND GADDI GOAT: HIGH ALTITUDE LIVESTOCK ANIMALS

    Directory of Open Access Journals (Sweden)

    Lakshya Veer Singh

    2013-06-01

    Full Text Available The present study was undertaken to characterize exon 1 and exon 2 sequence of one of fecundity genes: GDF9 (Growth differentiation factor 9, in high altitude livestock animal (Yak and Gaddi goat. Six nucleotide differences were identified between sheep (AF078545 and goats (EF446168 in exon 1 and exon 2. Sequencing revealed nine novel single nucleotide mutations in exon 1 and exon 2 of Indian yak that compared with Bos taurus (GQ922451. These results preliminarily showed that the GDF9 gene might be a major gene that influences prolificacy of Gaddi goats and Indian yak.

  20. Widespread signals of convergent adaptation to high altitude in Asia and America

    OpenAIRE

    Foll, Matthieu; Gaggiotti, Oscar E; Daub, Josephine T; Vatsiou, Alexandra; Excoffier, Laurent

    2014-01-01

    This work has been made possible by Swiss National Science Foundation grants No. 3100A0-126074, 31003A-143393, and CRSII3_141940 to L.E. O.E.G. was supported by French ANR grant No 09-GENM-017-001 and by the Marine Alliance for Science and Technology for Scotland (MASTS). Living at high altitude is one of the most difficult challenges that humans had to cope with during their evolution. Whereas several genomic studies have revealed some of the genetic bases of adaptations in Tibetan, Andea...

  1. New Heights with High-Altitude Balloon Launches for Effective Student Learning and Environmental Awareness

    Science.gov (United States)

    Voss, H. D.; Dailey, J. F.; Takehara, D.; Krueger, J. M.

    2009-12-01

    Over a seven-year period Taylor University, an undergraduate liberal art school, has successfully launched and recovered over 200 sophisticated student payloads to altitudes between 20-33 km (100% success with rapid recovery) with flight times between 2 to 6 hrs. All of the payloads included two GPS tracking systems, cameras and monitors, a 110 kbit down link, an uplink command capability for educational experiments (K-12 and undergrad). Launches were conducted during the day and night, with multiple balloons, with up to 10 payloads for experiments, and under varying weather and upper atmospheric conditions. The many launches in a short period of time allowed the payload bus design to evolve toward increased performance, reliability, standardization, simplicity, and modularity for low-cost launch services. Through NSF and NASA grants, the program has expanded leading to over 50 universities trained at workshops to implement high altitude balloon launches in the classroom. A spin-off company (StraoStar Systems LLC) now sells the high-altitude balloon system and facilitates networking between schools. This high-altitude balloon program helps to advance knowledge and understanding across disciplines by giving students and faculty rapid and low-cost access to earth/ecology remote sensing from high altitude, insitu and limb atmospheric measurements, near-space stratosphere measurements, and IR/UV/cosmic ray access to the heavens. This new capability is possible by exposing students to recent advances in MEMS technology, nanotechnology, wireless telecommunication systems, GPS, DSPs and other microchip miniaturizations to build collaboration among science faculty, and provides quantitative assessment of the learning outcomes. Furthermore this program has generated many front page news reports along with significant TV coverage because of its connection to hands-on learning for students and adults of all ages, connection to understanding climate change and ways to mitigate

  2. Noninvasive Assessment of Excessive Erythrocytosis as a Screening Method for Chronic Mountain Sickness at High Altitude.

    Science.gov (United States)

    Vyas, Kaetan J; Danz, David; Gilman, Robert H; Wise, Robert A; León-Velarde, Fabiola; Miranda, J Jaime; Checkley, William

    2015-06-01

    Vyas, Kaetan J., David Danz, Robert H. Gilman, Robert A. Wise, Fabiola León-Velarde, J. Jaime Miranda, and William Checkley. Noninvasive assessment of excessive erythrocytosis as a screening method for chronic mountain sickness at high altitude. High Alt Med Biol 16:162-168, 2015.--Globally, over 140 million people are at risk of developing chronic mountain sickness, a common maladaptation to life at high altitude (>2500 meters above sea level). The diagnosis is contingent upon the identification of excessive erythrocytosis (EE). Current best practices to identify EE require a venous blood draw, which is cumbersome for large-scale surveillance. We evaluated two point-of-care biomarkers to screen for EE: noninvasive spot-check tests of total hemoglobin and oxyhemoglobin saturation (Pronto-7, Masimo Corporation). We conducted paired evaluations of total serum hemoglobin from a venous blood draw and noninvasive, spot-check testing of total hemoglobin and oxyhemoglobin saturation with the Pronto-7 in 382 adults aged ≥35 years living in Puno, Peru (3825 meters above sea level). We used the Bland-Altman method to measure agreement between the noninvasive hemoglobin assessment and the gold standard lab hemoglobin analyzer. Mean age was 58.8 years and 47% were male. The Pronto-7 test was unsuccessful in 21 (5%) participants. Limits of agreement between total hemoglobin measured via venous blood draw and the noninvasive, spot-check test ranged from -2.8 g/dL (95% CI -3.0 to -2.5) to 2.5 g/dL (95% CI 2.2 to 2.7), with a bias of -0.2 g/dL (95% CI -0.3 to -0.02) for the difference between total hemoglobin and noninvasive hemoglobin concentrations. Overall, the noninvasive spot-check test of total hemoglobin had a better area under the receiver operating characteristic curve compared to oxyhemoglobin saturation for the identification of EE as measured by a gold standard laboratory hemoglobin analyzer (0.96 vs. 0.82; p<0.001). Best cut-off values to screen for EE with

  3. Studies on radioactivities of dust samples in the air at high altitudes

    International Nuclear Information System (INIS)

    Kohara, Eri; Muronoi, Naohiro

    2015-01-01

    The radioactivity concentrations of airborne dust samples were studied. The samples had been collected at high altitude by the Japan Air Self-Defense Force from April 2013 to March 2014. The obtained data were used for gross beta radioactivity analysis and gamma nuclide analysis. It is shown that cesium 137 was mainly detected at the 10 km and 3 km altitude of central area of Japan in several samples. Gaseous radioiodine was not detected in all the samples. Radioactive xenon was detected but the concentration did not show significant difference to the background level. (author)

  4. Solar Cell to Support Perpetual Flight of High Altitude Long Endurance UAV ITB

    Science.gov (United States)

    Luqmanul Hakim, Muhammad; Silitonga, Faber Y.; Rosid, Nurhayyan H.; Mochammad Agoes Moelyadi, Ing., Dr.

    2018-04-01

    Research on a High Altitude Long Endurance (HALE) Unmanned Aerial Vehicle (UAV) is currently being conducted at Bandung Institute of Technology to reach the flight duration needed and to get the solution of today’s challenges, minimizing pollution. Besides the good aerodynamic efficiency needed, energy resource is now becoming important. The energy resource must have a good endurance, easy to get, and of course, less pollution. Discussion in this paper is about the analysis of power needed by HALE UAV while takeoff and cruise flight conditions, and then determine the amount of solar cell and battery needed by the UAV.

  5. Dry deposition of sulphur at a high-altitude background station in South Africa

    CSIR Research Space (South Africa)

    Zunckel, M

    1999-10-01

    Full Text Available station also plays a role in the observed day-to-day variation as pollutants are trapped immediately below this layer. The pressure difference between the base of the absolutely stable layer and the surface pressure at Ben MacDhui is used to indicate... AT A HIGH-ALTITUDE BACKGROUND STATION IN SOUTH AFRICA MARK ZUNCKEL1;2 , STUART PIKETH1 and TALI FREIMAN1 1 Climatology Research Group, University of Witwatersrand, Johannesburg, South Africa; 2 CSIR Environmentek, P.O. Box 17001, Congella, South Africa...

  6. Nutritional Strategies for the Preservation of Fat Free Mass at High Altitude

    Directory of Open Access Journals (Sweden)

    Stacie L. Wing-Gaia

    2014-02-01

    Full Text Available Exposure to extreme altitude presents many physiological challenges. In addition to impaired physical and cognitive function, energy imbalance invariably occurs resulting in weight loss and body composition changes. Weight loss, and in particular, loss of fat free mass, combined with the inherent risks associated with extreme environments presents potential performance, safety, and health risks for those working, recreating, or conducting military operations at extreme altitude. In this review, contributors to muscle wasting at altitude are highlighted with special emphasis on protein turnover. The article will conclude with nutritional strategies that may potentially attenuate loss of fat free mass during high altitude exposure.

  7. AltitudeOmics: Resetting of cerebrovascular CO2 reactivity following acclimatization to high altitude

    Directory of Open Access Journals (Sweden)

    Jui-Lin eFan

    2016-01-01

    Full Text Available Previous studies reported enhanced cerebrovascular CO2 reactivity upon ascent to high altitude using linear models. However, there is evidence that this response may be sigmoidal in nature. Moreover, it was speculated that these changes at high altitude are mediated by alterations in acid-base buffering. Accordingly, we reanalyzed previously published data to assess middle cerebral blood flow velocity (MCAv responses to modified rebreathing at sea level (SL, upon ascent (ALT1 and following 16 days of acclimatization (ALT16 to 5,260 m in 21 lowlanders. Using sigmoid curve fitting of the MCAv responses to CO2, we found the amplitude (95% vs. 129%, SL vs. ALT1, 95% confidence intervals (CI [77, 112], [111, 145], respectively, P=0.024 and the slope of the sigmoid response (4.5 vs. 7.5 %/mmHg, SL vs. ALT1, 95% CIs [3.1, 5.9], [6.0, 9.0], respectively, P=0.026 to be enhanced at ALT1, which persisted with acclimatization at ALT16 (amplitude: 177%, 95% CI [139, 215], P<0.001; slope: 10.3 %/mmHg, 95% CI [8.2, 12.5], P=0.003 compared to SL. Meanwhile, the sigmoidal response midpoint was unchanged at ALT1 (SL: 36.5 mmHg; ALT1: 35.4 mmHg, 95% CIs [34.0, 39.0], [33.1, 37.7], respectively, P=0.982, while it was reduced by ~7 mmHg at ALT16 (28.6 mmHg, 95% CI [26.4, 30.8], P=0.001 vs. SL, indicating leftward shift of the cerebrovascular CO2 response to a lower arterial partial pressure of CO2 (PaCO2 following acclimatization to altitude. Sigmoid fitting revealed a leftward shift in the midpoint of the cerebrovascular response curve which could not be observed with linear fitting. These findings demonstrate that there is resetting of the cerebrovascular CO2 reactivity operating point to a lower PaCO2 following acclimatization to high altitude. This cerebrovascular resetting is likely the result of an altered acid-base buffer status resulting from prolonged exposure to the severe hypocapnia associated with ventilatory acclimatization to high altitude.

  8. Creation of a Dynamical Stratospheric Turbulence Forecasting and Nowcasting Tool for High Altitude Airships and Other Aircraft

    National Research Council Canada - National Science Library

    Fritts, David C

    2008-01-01

    ... for which significant wave and turbulence activity may pose an operational or functional risk. The specific goal for MDA purposes was to create a forecasting methodology for turbulence activity at the expected High Altitude Airship (HAA...

  9. The lactate paradox revisited in lowlanders during acclimatization to 4100 m and in high-altitude natives

    DEFF Research Database (Denmark)

    Van Hall, Gerrit; Lundby, C; Araoz, M

    2009-01-01

    Chronic hypoxia has been proposed to induce a closer coupling in human skeletal muscle between ATP utilization and production in both lowlanders (LN) acclimatizing to high altitude and high-altitude natives (HAN), linked with an improved match between pyruvate availability and its use...... and remained at this higher level during the acclimatization period. HAN had similar high values; however, at the moment of exhaustion their muscle lactate, ADP and IMP content and Cr/PCr ratio were higher than in LN. In conclusion, sea-level residents in the course of acclimatization to high altitude did...... not exhibit a reduced capacity for the active muscle to produce lactate. Thus, the lactate paradox concept could not be demonstrated. High-altitude natives from the Andes actually exhibit a higher anaerobic energy production than lowlanders after 8 weeks of acclimatization reflected by an increased muscle...

  10. HURRICANE AND SEVERE STORM SENTINEL (HS3) GLOBAL HAWK HIGH ALTITUDE MMIC SOUNDING RADIOMETER (HAMSR) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The Hurricane and Severe Storm Sentinel (HS3) Global Hawk High Altitude MMIC Sounding Radiometer (HAMSR) datasets include measurements gathered by the HAMSR...

  11. Cradle Cap (For Parents)

    Science.gov (United States)

    ... Safe Videos for Educators Search English Español Cradle Cap (Infantile Seborrheic Dermatitis) KidsHealth / For Parents / Cradle Cap ( ... many babies develop called cradle cap. About Cradle Cap Cradle cap is the common term for seborrheic ...

  12. Integrated Modelling of an Unmanned High-Altitude Solar-Powered Aircraft for Control Law Design Analysis

    OpenAIRE

    Klöckner, Andreas; Leitner, Martin; Schlabe, Daniel; Looye, Gertjan

    2013-01-01

    Solar-powered high-altitude unmanned platforms are highly optimized and integrated aircraft. In order to account for the complex, multi-physical interactions between their systems, we propose using integrated simulation models throughout the aircraft’s life cycle. Especially small teams with limited ressources should benefit from this approach. In this paper, we describe our approach to an integrated model of the Electric High-Altitude Solar-Powered Aircraft ELHASPA. It includes aspects of th...

  13. Research on the sewage treatment in high altitude region based on Lhasa Sewage Treatment Plant

    Science.gov (United States)

    Xu, Jin; Li, Shuwen

    2017-12-01

    Sewage treatment is of great significance to enhance environmental quality, consolidate pollution prevention and ecological protection, and ensure sustainable economic and social development in high altitude region. However, there are numerous difficulties in sewage treatment due to the alpine climate, the relatively low economic development level, and the backward operation and management styles, etc. In this study, the characteristics of influent quality in the sewage treatment plant in Lhasa are investigated by analysing the influent BOD5/COD and BOD5/TN, comparing key indexes recorded from 2014 to 2016 with the hinterland. Results show that the concentration of influent COD, BOD5, NH3-N and SS in the Lhasa sewage treatment plant, in which the sewage belongs to low-concentration urban sewage, is smaller than that in the domestic sewage treatment plants in the mainland. The concentration ratio of BOD5/COD and BOD5/TN is below 0.4 and 4, which indicates that the biodegradation is poor and the carbon sources are in bad demand. The consequences obtained play a vital role in the design, operation and management of sewage treatment plants in high altitude region.

  14. The role of oxygen-increased respirator in humans ascending to high altitude

    Directory of Open Access Journals (Sweden)

    Shen Guanghao

    2012-08-01

    Full Text Available Abstract Background Acute mountain sickness (AMS is common for people who live in low altitude areas ascending to the high altitude. Many instruments have been developed to treat mild cases of AMS. However, long-lasting and portable anti-hypoxia equipment for individual is not yet available. Methods Oxygen-increased respirator (OIR has been designed to reduce the risk of acute mountain sickness in acute exposure to low air pressure. It can increase the density of oxygen by increasing total atmospheric pressure in a mask. Male subjects were screened, and eighty-eight were qualified to perform the experiments. The subjects were divided into 5 groups and were involved in some of the tests at 4 different altitudes (Group 1, 2: 3700 m; Group 3,4,5: 4000 m, 4700 m, 5380 m with and without OIR. These tests include heart rate, saturation of peripheral oxygen (SpO2, malondialdehyde (MDA, superoxide dismutase (SOD, blood lactate (BLA and PWC (physical work capacity -170. Results The results showed that higher SpO2, lower heart rate (except during exercise and better recovery of heart rate were observed from all the subjects ’with OIR’ compared with ’without OIR’ (P Conclusions We suggested that OIR may play a useful role in protecting people ascending to high altitude before acclimatization.

  15. Cooperative Scheduling of Imaging Observation Tasks for High-Altitude Airships Based on Propagation Algorithm

    Directory of Open Access Journals (Sweden)

    He Chuan

    2012-01-01

    Full Text Available The cooperative scheduling problem on high-altitude airships for imaging observation tasks is discussed. A constraint programming model is established by analyzing the main constraints, which takes the maximum task benefit and the minimum cruising distance as two optimization objectives. The cooperative scheduling problem of high-altitude airships is converted into a main problem and a subproblem by adopting hierarchy architecture. The solution to the main problem can construct the preliminary matching between tasks and observation resource in order to reduce the search space of the original problem. Furthermore, the solution to the sub-problem can detect the key nodes that each airship needs to fly through in sequence, so as to get the cruising path. Firstly, the task set is divided by using k-core neighborhood growth cluster algorithm (K-NGCA. Then, a novel swarm intelligence algorithm named propagation algorithm (PA is combined with the key node search algorithm (KNSA to optimize the cruising path of each airship and determine the execution time interval of each task. Meanwhile, this paper also provides the realization approach of the above algorithm and especially makes a detailed introduction on the encoding rules, search models, and propagation mechanism of the PA. Finally, the application results and comparison analysis show the proposed models and algorithms are effective and feasible.

  16. Correlations between the simulated military tasks performance and physical fitness tests at high altitude

    Directory of Open Access Journals (Sweden)

    Eduardo Borba Neves

    2017-11-01

    Full Text Available The aim of this study was to investigate the Correlations between the Simulated Military Tasks Performance and Physical Fitness Tests at high altitude. This research is part of a project to modernize the physical fitness test of the Colombian Army. Data collection was performed at the 13th Battalion of Instruction and Training, located 30km south of Bogota D.C., with a temperature range from 1ºC to 23ºC during the study period, and at 3100m above sea level. The sample was composed by 60 volunteers from three different platoons. The volunteers start the data collection protocol after 2 weeks of acclimation at this altitude. The main results were the identification of a high positive correlation between the 3 Assault wall in succession and the Simulated Military Tasks performance (r = 0.764, p<0.001, and a moderate negative correlation between pull-ups and the Simulated Military Tasks performance (r = -0.535, p<0.001. It can be recommended the use of the 20-consecutive overtaking of the 3 Assault wall in succession as a good way to estimate the performance in operational tasks which involve: assault walls, network of wires, military Climbing Nets, Tarzan jump among others, at high altitude.

  17. Serum immunoreactive erythropoietin in high altitude natives with and without excessive erythrocytosis.

    Science.gov (United States)

    León-Velarde, F; Monge, C C; Vidal, A; Carcagno, M; Criscuolo, M; Bozzini, C E

    1991-05-01

    We report the estimation of blood hemoglobin (Hb), arterial blood oxygen saturation (SaO2), and serum immunoreactive erythropoietin (siEPO) in a group of Peruvian workers residing in Cerro de Pasco at 4300 m showing "excessive erythrocytosis" (EE, Monge's disease, chronic mountain sickness). These estimates were compared with those of humans residing either in Cerro de Pasco and showing "normal erythrocytosis" (NE) or in Lima (sea level, SL) to determine whether Hb and SaO2 are related to siEPO in high altitude (HA) natives with NE or EE. The three parameters showed statistically significant differences between HA and SL groups--the values in SL being lower. Significant differences were also found between NE and EE groups in Hb and SaO2. There was no statistical difference in siEPo between the two groups. The results indicate, therefore, that HA residents who develop EE are not distinguishable from residents who develop NE on the basis of estimates of siEPO. As a result, siEPO and Hb do not show a dose-response relationship in HA residents, and variation in EPO does not explain the striking variation in Hb at high altitudes.

  18. Flight simulation program for high altitude long endurance unmanned vehicle; Kokodo mujinki no hiko simulation program

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, H.; Hashidate, M. [National Aerospace Laboratory, Tokyo (Japan)

    1995-11-01

    An altitude of about 20 km has the atmospheric density too dilute for common aircraft, and the air resistance too great for satellites. Attention has been drawn in recent years on a high-altitude long-endurance unmanned vehicle that flies at this altitude for a long period of time to serve as a wave relaying base and perform traffic control. Therefore, a development was made on a flight simulation program to evaluate and discuss the guidance and control laws for the high-altitude unmanned vehicle. Equations of motion were derived for three-dimensional six freedom and three-dimensional three freedom. Aerodynamic characteristics of an unmanned vehicle having a Rectenna wing were estimated, and formulation was made according to the past research results on data of winds that the unmanned vehicle is anticipated to encounter at an altitude of 20 km. Noticing the inside of a horizontal plane, a proposal was given on a guidance law that follows a given path. A flight simulation was carried out to have attained a prospect that the unmanned vehicle may be enclosed in a limited space even if the vehicle is encountered with a relatively strong wind. 18 refs., 20 figs., 1 tab.

  19. Genotyping the High Altitude Mestizo Ecuadorian Population Affected with Prostate Cancer

    Directory of Open Access Journals (Sweden)

    Andrés López-Cortés

    2017-01-01

    Full Text Available Prostate cancer (PC is the second most commonly diagnosed type of cancer in males with 1,114,072 new cases in 2015. The MTHFR enzyme acts in the folate metabolism, which is essential in methylation and synthesis of nucleic acids. MTHFR C677T alters homocysteine levels and folate assimilation associated with DNA damage. Androgens play essential roles in prostate growth. The SRD5A2 enzyme metabolizes testosterone and the V89L polymorphism reduces in vivo SRD5A2 activity. The androgen receptor gene codes for a three-domain protein that contains two polymorphic trinucleotide repeats (CAG, GGC. Therefore, it is essential to know how PC risk is associated with clinical features and polymorphisms in high altitude Ecuadorian mestizo populations. We analyzed 480 healthy and 326 affected men from our three retrospective case-control studies. We found significant association between MTHFR C/T (odds ratio [OR] = 2.2; P=0.009, MTHFR C/T+T/T (OR = 2.22; P=0.009, and PC. The SRD5A2 A49T substitution was associated with higher pTNM stage (OR = 2.88; P=0.039 and elevated Gleason grade (OR = 3.15; P=0.004. Additionally, patients with ≤21 CAG repeats have an increased risk of developing PC (OR = 2.99; P<0.001. In conclusion, genotype polymorphism studies are important to characterize genetic variations in high altitude mestizo populations.

  20. The paradox of extreme high-altitude migration in bar-headed geese Anser indicus

    Science.gov (United States)

    Hawkes, L. A.; Balachandran, S.; Batbayar, N.; Butler, P. J.; Chua, B.; Douglas, D. C.; Frappell, P. B.; Hou, Y.; Milsom, W. K.; Newman, S. H.; Prosser, D. J.; Sathiyaselvam, P.; Scott, G. R.; Takekawa, J. Y.; Natsagdorj, T.; Wikelski, M.; Witt, M. J.; Yan, B.; Bishop, C. M.

    2013-01-01

    Bar-headed geese are renowned for migratory flights at extremely high altitudes over the world's tallest mountains, the Himalayas, where partial pressure of oxygen is dramatically reduced while flight costs, in terms of rate of oxygen consumption, are greatly increased. Such a mismatch is paradoxical, and it is not clear why geese might fly higher than is absolutely necessary. In addition, direct empirical measurements of high-altitude flight are lacking. We test whether migrating bar-headed geese actually minimize flight altitude and make use of favourable winds to reduce flight costs. By tracking 91 geese, we show that these birds typically travel through the valleys of the Himalayas and not over the summits. We report maximum flight altitudes of 7290 m and 6540 m for southbound and northbound geese, respectively, but with 95 per cent of locations received from less than 5489 m. Geese travelled along a route that was 112 km longer than the great circle (shortest distance) route, with transit ground speeds suggesting that they rarely profited from tailwinds. Bar-headed geese from these eastern populations generally travel only as high as the terrain beneath them dictates and rarely in profitable winds. Nevertheless, their migration represents an enormous challenge in conditions where humans and other mammals are only able to operate at levels well below their sea-level maxima. PMID:23118436

  1. Ontogenic development of spermatids during spermiogenesis in the high altitude bunchgrass lizard (Sceloporus bicanthalis).

    Science.gov (United States)

    Rheubert, Justin; Touzinsky, Katherine; Hernández-Gallegos, Oswaldo; Granados-González, Gisela; Gribbins, Kevin

    2012-04-01

    The body of ultrastructural data on spermatid characters during spermiogenesis continues to grow in reptiles, but is still relatively limited within the squamates. This study focuses on the ontogenic events of spermiogenesis within a viviparous and continually spermatogenic lizard, from high altitude in Mexico. Between the months of June and August, testicular tissues were collected from eight spermatogenically active bunchgrass lizards (Sceloporus bicanthalis) from Nevado de Toluca, México. The testicular tissues were processed for transmission electron microscopy and analyzed to access the ultrastructural differences between spermatid generations during spermiogenesis. Interestingly, few differences exist between S. bicanthalis spermiogenesis when compared with what has been described for other saurian squamates. Degrading and coiling membrane structures similar to myelin figures were visible within the developing acrosome that are likely remnants from Golgi body vesicles. During spermiogenesis, an electron lucent area between the subacrosomal space and the acrosomal medulla was observed, which has been observed in other squamates but not accurately described. Thus, we elect to term this region the acrosomal lucent ridge. This study furthers the existing knowledge of spermatid development in squamates, which could be useful in future work on the reproductive systems in high altitude viviparous lizard species.

  2. Global dose to man from proposed NNTRP high altitude nuclear tests

    International Nuclear Information System (INIS)

    Peterson, K.R.

    1975-05-01

    Radionuclide measurements from past high altitude nuclear testing have enabled development of a model to estimate surface deposition and doses from 400 kt of fission products injected in winter within the Pacific Test Area at altitudes in excess of 50 km. The largest 30-year average dose to man is about 10 millirem and occurs at 30 0 to 50 0 N latitude. The principal contributor to this dose is external gamma radiation from gross fission products. Individual doses from 90 Sr via the forage-cow-milk pathway and 137 Cs via the pasture-meat pathway are about 1/5 the gross fission product doses. The global 30-year population dose is 3 x 10 7 person-rem, which compares with a 30-year natural background population dose of 1 X 10 10 person-rem. Due in large part to the global distribution of population, over 98 percent of the global person-rem from the proposed high altitude tests is received in the Northern Hemisphere, while about 75 percent of the total population dose occurs within the 30 0 --50 0 N latitude belt. Detonations in summer would decrease the global dose by about a factor of three. (U.S.)

  3. Short-term cardiorespiratory adaptation to high altitude in children compared with adults.

    Science.gov (United States)

    Kriemler, S; Radtke, T; Bürgi, F; Lambrecht, J; Zehnder, M; Brunner-La Rocca, H P

    2016-02-01

    As short-term cardiorespiratory adaptation to high altitude (HA) exposure has not yet been studied in children, we assessed acute mountain sickness (AMS), hypoxic ventilatory response (HVR) at rest and maximal exercise capacity (CPET) at low altitude (LA) and HA in pre-pubertal children and their fathers. Twenty father-child pairs (11 ± 1 years and 44 ± 4 years) were tested at LA (450 m) and HA (3450 m) at days 1, 2, and 3 after fast ascent (HA1/2/3). HVR was measured at rest and CPET was performed on a cycle ergometer. AMS severity was mild to moderate with no differences between generations. HVR was higher in children than adults at LA and increased at HA similarly in both groups. Peak oxygen uptake (VO2 peak) relative to body weight was similar in children and adults at LA and decreased significantly by 20% in both groups at HA; maximal heart rate did not change at HA in children while it decreased by 16% in adults (P < 0.001). Changes in HVR and VO2 peak from LA to HA were correlated among the biological child-father pairs. In conclusion, cardiorespiratory adaptation to altitude seems to be at least partly hereditary. Even though children and their fathers lose similar fractions of aerobic capacity going to high altitude, the mechanisms might be different. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  4. Beta-fibrinogen allele frequencies in Peruvian Quechua, a high-altitude native population.

    Science.gov (United States)

    Rupert, J L; Devine, D V; Monsalve, M V; Hochachka, P W

    1999-06-01

    Elevated hematocrits, which are found in many high-altitude populations, increase the oxygen-carrying capacity of blood and may represent an adaptation to hypoxic environments. However, as high hematocrit increases blood viscosity, which in turn is associated with hypertension and heart disease, it may be advantageous for high-altitude populations to limit other factors that contribute to increased blood viscosity. One such factor is the plasma concentration of the coagulation protein fibrinogen. Several common polymorphisms in the beta-fibrinogen gene have been identified that affect fibrinogen concentrations. We determined the allele frequencies of three of these polymorphisms (G/A-455(HaeIII), C/T-148(HindIII), and G/A+448(MnlI)) in sample groups drawn from three populations: Quechua-speaking natives living at over 3,200 m in the Peruvian Andes, North American natives (Na-Dene) from coastal British Columbia, and Caucasian North Americans. The frequencies of the alleles previously shown to be associated with increased fibrinogen levels were so low in the Quechuas that their presence could be accounted for solely by genetic admixture with Caucasians. Frequencies in the Na-Dene, a Native American group unrelated to the Quechua, were not significantly different from those in Caucasians.

  5. Cerebral pressure-flow relationship in lowlanders and natives at high altitude.

    Science.gov (United States)

    Smirl, Jonathan D; Lucas, Samuel J E; Lewis, Nia C S; duManoir, Gregory R; Dumanior, Gregory R; Smith, Kurt J; Bakker, Akke; Basnyat, Aperna S; Ainslie, Philip N

    2014-02-01

    We investigated if dynamic cerebral pressure-flow relationships in lowlanders are altered at high altitude (HA), differ in HA natives and after return to sea level (SL). Lowlanders were tested at SL (n=16), arrival to 5,050 m, after 2-week acclimatization (with and without end-tidal PO2 normalization), and upon SL return. High-altitude natives (n=16) were tested at 5,050 m. Testing sessions involved resting spontaneous and driven (squat-stand maneuvers at very low (VLF, 0.05 Hz) and low (LF, 0.10 Hz) frequencies) measures to maximize blood pressure (BP) variability and improve assessment of the pressure-flow relationship using transfer function analysis (TFA). Blood flow velocity was assessed in the middle (MCAv) and posterior (PCAv) cerebral arteries. Spontaneous VLF and LF phases were reduced and coherence was elevated with acclimatization to HA (Pflow coupling. However, when BP was driven, both the frequency- and time-domain metrics were unaltered and comparable with HA natives. Acute mountain sickness was unrelated to TFA metrics. In conclusion, the driven cerebral pressure-flow relationship (in both frequency and time domains) is unaltered at 5,050 m in lowlanders and HA natives. Our findings indicate that spontaneous changes in TFA metrics do not necessarily reflect physiologically important alterations in the capacity of the brain to regulate BP.

  6. Hemoglobin and hematocrit values of Saudi newborns in the high altitude of Abha, Saudi Arabia

    International Nuclear Information System (INIS)

    Bassuni, W.; Asindi, A.A.; Mustafa, F.S.; Hassan, B.; Din, Z.S.; Kumar, R.K.

    1996-01-01

    A study was designed to determine the red cell values (hemoglobin and hematocrit) of neonates born in the high altitude of Abha and to compare these values with known values of other lowland areas of Saudi Arabia. From the cord blood of 587 normal, appropriate for gestational age and term infants born in 1993 in Abha Maternity Hospital, the ranges of Hb and Hct were 130 to 240 g/L and 0.24 to 0.79 L/L respectively. The mean Hb was 187 g/L. There was no significant difference between the male and female values. Also, 17% of the infants in this study were polycythemic, while no polycythemia was recorded in these lowland areas and only 2% to 4% in the general global newborn population. It was therefore revealed that Abha newborns had higher red cell values at the birth when compared to other newborns in the low altitude areas of Riyadh and Jeddah (P<0.001). We postulate that high altitude (2700 meters above sea level) of Abha, and therefore its relative hypoxia, has induced high red cell values in infants born in the city. The phenomenon therefore warrants the adoption of higher red cell reference values and not necessarily those already documented in other Saudi new born populations. (author)

  7. Relative Match Intensities at High Altitude in Highly-Trained Young Soccer Players (ISA3600).

    Science.gov (United States)

    Buchheit, Martin; Hammond, Kristal; Bourdon, Pitre C; Simpson, Ben M; Garvican-Lewis, Laura A; Schmidt, Walter F; Gore, Christopher J; Aughey, Robert J

    2015-03-01

    To compare relative match intensities of sea-level versus high-altitude native soccer players during a 2-week camp at 3600 m, data from 7 sea-level (Australian U17 National team, AUS) and 6 high-altitude (a Bolivian U18 team, BOL) native soccer players were analysed. Two matches were played at sea-level and three at 3600 m on Days 1, 6 and 13. The Yo-Yo Intermittent recovery test (vYo-YoIR1) was performed at sea-level, and on Days 3 and 10. Match activity profiles were measured via 10-Hz GPS. Distance covered >14.4 km.h(-1) (D>14.4 km·h(-1)) and >80% of vYo-YoIR1 (D>80%vYo-YoIR1) were examined. Upon arrival at altitude, there was a greater decrement in vYo-YoIR1 (Cohen's d +1.0, 90%CL ± 0.8) and D>14.4 km·h(-1) (+0.5 ± 0.8) in AUS. D>14.4 km.h(-1) was similarly reduced relative to vYo-YoIR1 in both groups, so that D>80%vYo-YoIR1 remained similarly unchanged (-0.1 ± 0.8). Throughout the altitude sojourn, vYo-YoIR1 and D>14.4 km·h(-1) increased in parallel in AUS, so that D>80%vYo-YoIR1 remained stable in AUS (+6.0%/match, 90%CL ± 6.7); conversely D>80%vYo-YoIR1 decreased largely in BOL (-12.2%/match ± 6.2). In sea-level natives competing at high-altitude, changes in match running performance likely follow those in high-intensity running performance. Bolivian data confirm that increases in 'fitness' do not necessarily translate into greater match running performance, but rather in reduced relative exercise intensity. Key pointsWhen playing at high-altitude, players may alter their activities during matches in relation to their transient maximal physical capacities, possibly to maintain a 'tolerable' relative exercise intensity.While there is no doubt that running performance per se in not the main determinant of match outcomes (Carling, 2013), fitness levels influence relative match intensity (Buchheit et al., 2012, Mendez-Villanueva et al., 2013), which in-turn may impact on decision making and skill performance (Rampinini et al., 2008).In the context of

  8. Modeling Commercial Turbofan Engine Icing Risk With Ice Crystal Ingestion

    Science.gov (United States)

    Jorgenson, Philip C. E.; Veres, Joseph P.

    2013-01-01

    The occurrence of ice accretion within commercial high bypass aircraft turbine engines has been reported under certain atmospheric conditions. Engine anomalies have taken place at high altitudes that have been attributed to ice crystal ingestion, partially melting, and ice accretion on the compression system components. The result was degraded engine performance, and one or more of the following: loss of thrust control (roll back), compressor surge or stall, and flameout of the combustor. As ice crystals are ingested into the fan and low pressure compression system, the increase in air temperature causes a portion of the ice crystals to melt. It is hypothesized that this allows the ice-water mixture to cover the metal surfaces of the compressor stationary components which leads to ice accretion through evaporative cooling. Ice accretion causes a blockage which subsequently results in the deterioration in performance of the compressor and engine. The focus of this research is to apply an engine icing computational tool to simulate the flow through a turbofan engine and assess the risk of ice accretion. The tool is comprised of an engine system thermodynamic cycle code, a compressor flow analysis code, and an ice particle melt code that has the capability of determining the rate of sublimation, melting, and evaporation through the compressor flow path, without modeling the actual ice accretion. A commercial turbofan engine which has previously experienced icing events during operation in a high altitude ice crystal environment has been tested in the Propulsion Systems Laboratory (PSL) altitude test facility at NASA Glenn Research Center. The PSL has the capability to produce a continuous ice cloud which are ingested by the engine during operation over a range of altitude conditions. The PSL test results confirmed that there was ice accretion in the engine due to ice crystal ingestion, at the same simulated altitude operating conditions as experienced previously in

  9. Inland and Near Shore Water Profiles Derived from the High Altitude Multiple Altimeter Beam Experimental Lidar (MABEL)

    Science.gov (United States)

    Jasinski, Michael F.; Stoll, Jeremy D.; Cook, William B.; Ondrusek, Michael; Stengel, Eric; Brunt, Kelly

    2016-01-01

    The Advanced Topographic Laser Altimeter System (ATLAS) on the Ice, Cloud, and Land Elevation Satellite (ICESat-2) mission is a six beam, low energy, high repetition rate, 532 nm laser transmitter with photon counting detectors. Although designed primarily for detecting height changes in icecaps, sea ice and vegetation, the polar-orbital satellite will observe global surface water during its designed three year life span, including inland water bodies, coasts, and open oceans. In preparation for the mission, an ICESat-2 prototype or the Multiple Altimeter Beam Experimental Lidar (MABEL), was built and flown on high altitude aircraft experiments over a range of inland and near-shore targets. The purpose was to test the ATLAS concept and to provide a database for developing an algorithm that detects along track surface water height and light penetration under a range of atmospheric and water conditions. The current analysis examines the datasets of three MABEL transects observed from 20 km above ground of coastal and inland waters conducted in 2012 and 2013. Transects ranged from about 2 to 12 km in length and included the middle Chesapeake Bay, the near shore Atlantic coast at Virginia Beach, and Lake Mead. Results indicate MABEL's high capability for retrieving surface water height statistics with a mean height precision of approximately 5-7 cm per 100m segment length. Profiles of attenuated subsurface backscatter, characterized using a Signal to Background Ratio written in Log10 base, or LSBR0, were observed over a range of 1.3 to 9.3 meters depending on water clarity and atmospheric background. Results indicate that observable penetration depth, although primarily dependent on water properties, was greatest when solar background rate was low. Near shore bottom reflectance was detected only at the Lake Mead site down to maximum of 10 m under a clear night sky and low turbidity of approximately 1.6 Nephelometric Turbidity Units (NTU). The overall results suggest

  10. Prevalence of high altitude pulmonary hypertension among the natives of Spiti Valley--a high altitude region in Himachal Pradesh, India.

    Science.gov (United States)

    Negi, Prakash Chand; Marwaha, Rajeev; Asotra, Sanjeev; Kandoria, Arvind; Ganju, Neeraj; Sharma, Rajesh; Kumar, Ravi V; Bhardwaj, Rajeev

    2014-12-01

    The study aimed to determine the prevalence of high altitude pulmonary hypertension (HAPH) and its predisposing factors among natives of Spiti Valley. A cross-sectional survey study was done on the permanent natives of Spiti Valley residing at an altitude of 3000 m to 4200 m. Demographic characteristics, health behavior, anthropometrics, and blood pressure were recorded. Investigations included recording of 12 lead electrocardiogram (ECG), SaO2 with pulse oximeter, spirometry and echocardiography study, and measurement of Hb levels using the cynmethhemoglobin method. HAPH was diagnosed using criteria; tricuspid regurgitation (TR) gradient of ≥46 mmHg. ECG evidence of RV overload on 12 lead ECG was documented based on presence of 2 out of 3 criteria; R>S in V1, right axis deviation or RV strain, T wave inversion in V1 and V2. Data of 1087 subjects were analyzed who were free of cardiorespiratory diseases to determine the prevalence of HAPH and its predisposing factors. HAPH was recorded in 3.23% (95% C.I. of 0.9-8.1%) and ECG evidence of right ventricular (RV) overload was 1.5% in the study population. Prevalence of HAPH was not different in men and women 2.63% vs. 3.54% p<0.2. Age (Z statistics of 3.4 p<0.0006), hypoxemia (Z statistics of 2.9 p<0.002), and erythrocythemia (Z statistics of 4.7 p<0.003) were independently associated with HAPH. Altitude of residence was not found to be significantly associated with HAPH, although there was a trend of increasing prevalence with increasing altitude. It can be concluded that HAPH is prevalent in 3.23% of natives of Spiti Valley. Increasing age, erythrocythemia and hypoxemia are independent predisposing factors.

  11. Death cap

    DEFF Research Database (Denmark)

    Rudbæk, Torsten R; Kofoed, Pernille Bouteloup; Bove, Jeppe

    2014-01-01

    Death cap (Amanita phalloides) is commonly found and is one of the five most toxic fungi in Denmark. Toxicity is due to amatoxin, and poisoning is a serious medical condition, causing organ failure with potential fatal outcome. Acknowledgement and clarification of exposure, symptomatic and focused...

  12. Design of a high altitude long endurance flying-wing solar-powered unmanned air vehicle

    Science.gov (United States)

    Alsahlani, A. A.; Johnston, L. J.; Atcliffe, P. A.

    2017-06-01

    The low-Reynolds number environment of high-altitude §ight places severe demands on the aerodynamic design and stability and control of a high altitude, long endurance (HALE) unmanned air vehicle (UAV). The aerodynamic efficiency of a §ying-wing configuration makes it an attractive design option for such an application and is investigated in the present work. The proposed configuration has a high-aspect ratio, swept-wing planform, the wing sweep being necessary to provide an adequate moment arm for outboard longitudinal and lateral control surfaces. A design optimization framework is developed under a MATLAB environment, combining aerodynamic, structural, and stability analysis. Low-order analysis tools are employed to facilitate efficient computations, which is important when there are multiple optimization loops for the various engineering analyses. In particular, a vortex-lattice method is used to compute the wing planform aerodynamics, coupled to a twodimensional (2D) panel method to derive aerofoil sectional characteristics. Integral boundary-layer methods are coupled to the panel method in order to predict §ow separation boundaries during the design iterations. A quasi-analytical method is adapted for application to flyingwing con¦gurations to predict the wing weight and a linear finite-beam element approach is used for structural analysis of the wing-box. Stability is a particular concern in the low-density environment of high-altitude flight for flying-wing aircraft and so provision of adequate directional stability and control power forms part of the optimization process. At present, a modified Genetic Algorithm is used in all of the optimization loops. Each of the low-order engineering analysis tools is validated using higher-order methods to provide con¦dence in the use of these computationally-efficient tools in the present design-optimization framework. This paper includes the results of employing the present optimization tools in the design of a

  13. Cane pruning on Chardonnay grapevine in the high-altitude regions of Southern Brazil

    Directory of Open Access Journals (Sweden)

    Filho José Luiz Marcon

    2016-01-01

    Full Text Available High-altitude regions of southern Brazil, located above 900 m above sea level, the cordon training with spur pruning is widely used because of easier application. In these regions, Chardonnay wine grape shows potential to produce quality wines, however, in commercial vineyards, the training system used has not provided productivities that makes economically viable the cultivation of this variety. Given this, the present study aimed to evaluate the effect of different cane-pruning systems on the vegetative, productive and enological potential of Chardonnay grapevines grown in the high-altitude region of Southern Brazil. The experiment was conducted in a commercial Chardonnay vineyard, located in São Joaquim – Santa Catarina State (28o17 ′39”S and 49∘ 55′56” W, to 1230 m a.s.l during 2015 and 2016 vintages. Chardonnay vines (grafted on 1103 Paulsen were planted in 2010, with a 3.0 m (row × 1.0 m (vine spacing. The treatments consisted of different cane-pruning systems: Cordon spur-pruning (control; Sylvoz; Cazenave; Capovolto; single Guyot and double Guyot. Pruning was performed in August of each year when the buds were in the green tip developmental stage. Data was analyzed by Scott Knott test (p < 0.05 following a randomized block design with four replicates, each consisting of 12 vines per plot. We observed higher yield in the Cazenave and double Guyot training system with three and two more tons of grapes than spur-pruning respectively. The bud fertility was higher in plants trained in double Guyot. Vines spur-pruned showed higher relation of leaf area: production, with values above 100 cm2 g−1 grape at 2016 vintage. Commercial maturity of grapes (soluble solids, acidity and polyphenols did not differ among training systems studied. The results suggest that cane-pruning systems could be an alternative to increase production efficiency of Chardonnay in high-altitude region of southern Brazil.

  14. Energy management strategy for solar-powered high-altitude long-endurance aircraft

    International Nuclear Information System (INIS)

    Gao, Xian-Zhong; Hou, Zhong-Xi; Guo, Zheng; Liu, Jian-Xia; Chen, Xiao-Qian

    2013-01-01

    Highlights: ► A new Energy Management Strategy (EMS) for high-altitude solar-powered aircraft is purposed. ► The simulations show that the aircraft can always keep the altitude above 16 km with the proposed EMS. ► The proposed EMS is capable to alleviate the power consumed for aircraft during night. ► The main technologies to improve the flight performance of aircraft are analyzed. - Abstract: Development of solar-powered High-Altitude Long-Endurance (HALE) aircraft has a great impact on both military and civil aviation industries since its features in high-altitude and energy source can be considered inexhaustible. Owing to the development constraints of rechargeable batteries, the solar-powered HALE aircraft must take amount of rechargeable batteries to fulfill the energy requirement in night, which greatly limits the operation altitude of aircraft. In order to solve this problem, a new Energy Management Strategy (EMS) is proposed based on the idea that the solar energy can be partly stored in gravitational potential in daytime. The flight path of HALE aircraft is divided into three stages. During the stage 1, the solar energy is stored in both lithium–sulfur battery and gravitational potential. The gravitational potential is released in stage 2 by gravitational gliding and the required power in stage 3 is supplied by lithium–sulfur battery. Correspondingly, the EMS is designed for each stage. The simulation results show that the aircraft can always keep the altitude above 16 km with the proposed EMS, and the power consumed during night can be also alleviated. Comparing with the current EMS, about 23.5% energy is remained in batteries with the proposed EMS during one day–night cycle. The sensitivities of the improvement of crucial technologies to the performance of aircraft are also analyzed. The results show that the enhancement of control and structural system, lithium–sulfur battery, and solar cell are ranked in descending order for the

  15. HSD is a better resuscitation fluid for hemorrhagic shock with pulmonary edema at high altitude.

    Science.gov (United States)

    Liu, Liang-Ming; Hu, De-Yao; Zhou, Xue-Wu; Liu, Jiang-Cang; Li, Ping

    2008-12-01

    To investigate the fluid tolerance of hemorrhagic shock with pulmonary edema (HSPE) at high altitude in unacclimated rats and the beneficial effect of 7.5% hypertonic saline/6% dextran (HSD). One hundred seventy-six Sprague-Dawley rats, transported to LaSa, Tibet, 3,760 m above the sea level, were anesthetized with sodium pentobarbital (30 mg/kg, i.p.) within 1 week. Hemorrhagic shock with pulmonary edema was induced by bloodletting (50 mmHg for 1 h) plus intravenous injection of oleic acid (50 microL/kg). Seventy-seven rats were equally divided into 11 groups (n = 7/group) including sham-operated control group; hemorrhagic shock control group; HSPE control group; HSPE plus 0.5-, 1.0-, 1.5-, 2.0-, or 3.0-fold volumes of lactated Ringer's solution (LR) groups; and HSPE plus 4, 6, and 8 mL/kg of HSD groups. Hemodynamic parameters including mean arterial blood pressure, left intraventricular systolic pressure, and the maximal change rate of intraventricular pressure rise or decline (+/-dp/dtmax) were observed at baseline and at 15, 30, 60, and 120 min after infusion; blood gases were measured at 30 and 120 min after infusion, and the water content of lung and brain was determined at 120 min after infusion. Additional 99 rats were used to observe the effect of these treatments on the survival time of HSPE rats; 0.5 volume of LR infusion slightly increased the mean arterial blood pressure, left intraventricular systolic pressure, and +/-dp/dtmax and prolonged the survival time of HSPE animals as compared with the HSPE group (P solution infusion, 1.5, 2, and 3 volumes, significantly deteriorated the hemodynamic parameters, increased the water content of lung, and decreased the survival time of HSPE animals. Hypertonic saline/6% dextran (4 - 8 mL/kg) significantly increased the hemodynamic parameters, improved the blood gases, decreased the water content of lung and brain, and prolonged the survival time of HSPE rats. Among the three dosages of HSD, 6 mL/kg of HSD had the

  16. Beta2-adrenergic receptor allele frequencies in the Quechua, a high altitude native population.

    Science.gov (United States)

    Rupert, J L; Monsalve, M V; Devine, D V; Hochachka, P W

    2000-03-01

    The beta2-adrenergic receptor is involved in the control of numerous physiological processes and, as the primary catecholamine receptor in the lungs, is of particular importance in the regulation of pulmonary function. There are several polymorphic loci in the beta2-adrenergic receptor gene that have alleles that alter receptor function, including two (A/G46, G/C79) that increase agonist sensitivity. As such a phenotype may increase vaso and bronchial dilation, thereby facilitating air and blood flow through the lungs, we hypothesized that selection may have favoured these alleles in high altitude populations as part of an adaptive strategy to deal with the hypoxic conditions characteristic of such environments. We tested this hypothesis by determining the allele frequencies for these two polymorphisms, as well one additional missense mutation (C/T491) and two silent mutations (G/A252 and C/A523) in 63 Quechua speaking natives from communities located between 3200 and 4200 m on the Peruvian altiplano. These frequencies were compared with those of two lowland populations, one native American (Na-Dene from the west coast of Canada) and one Caucasian of Western European descent. The Quechua manifest many of the pulmonary characteristics of high altitude populations and differences in allele frequencies between the Quechua and lowlanders could be indicative of a selective advantage conferred by certain genotypes in high altitude environments. Allele frequencies varied between populations at some loci and patterns of linkage disequilibrium differed between the old-world and new-world samples; however, as these populations are not closely related, significant variation would be expected due to stochastic effects alone. Neither of the alleles associated with increased receptor sensitivity (A46, G79) was significantly over-represented in the Quechua compared with either lowland group. The Quechua were monomorphic for the C allele at base 79. This variant has been

  17. Percutaneous closure of patent arterial ducts in patients from high altitude: a sub-Saharan experience.

    Science.gov (United States)

    Tefera, Endale; Qureshi, Shakeel A; Bermudez-Cañete, Ramòn; Rubio, Lola

    2015-01-01

    At high altitude, patent arterial ducts tend to be larger and associated with pulmonary hypertension. Patent ductus arteriosus device closure in this background could be challenging. We report our experience with percutaneous closure of patent arterial ducts using a variety of devices in patients residing in a high altitude. This is a retrospective review of the case records of 145 patients (age 9 months-20 years, mean 5.6 ± 3.9 years, and weight 7-54 kg, mean 17.7 ± 9.4) with duct sizes ranging between 2 and 21 mm, (mean, 5.8 ± 2.7) who underwent percutaneous closure of patent arterial ducts. One hundred thirty-six (93.8%) of the patients were from a geographic area of 2100-2800 m above sea level. Successful device closure was achieved in 143 cases. It was difficult to achieve device stability in two patients with expansile ducts. Therefore, they were treated surgically. The devices used were various types of duct occluder devices in 131 patients, while atrial and ventricular septal occluders were used in eight patients. For the group, mean systolic pulmonary artery (PA) pressure decreased from 47.0 ± 16.7 mmHg before occlusion to 29.0 ± 7.4 mmHg after occlusion (P ≤ 0.001)., mean diastolic PA pressure from 25.0 ± 10.9 mmHg to 14.8 ± 6.0 mmHg and the average mean PA pressure decreased from 35.9 ± 13.5 mmHg to 21.1 ± 6.5 mmHg. Complications (4.8%) included device and coil embolization, bleeding, and pulse loss. On follow-up (mean duration of 36.1 ± 12.1 months, range 12-62 months), 137 patients were in functional class 1, 3 had residual shunt, 2 had device migration and one patient had persisting pulse loss. Successful duct closure was achieved in the vast majority of patients, even though the ducts were larger and significant number of them had pulmonary hypertension in this high altitude group. There was a relatively higher incidence of residual shunts and device migration in this series, generally due to the nonavailability of optimal device and

  18. Reduced blood flow through intrapulmonary arteriovenous anastomoses during exercise in lowlanders acclimatizing to high altitude.

    Science.gov (United States)

    Boulet, Lindsey M; Lovering, Andrew T; Tymko, Michael M; Day, Trevor A; Stembridge, Mike; Nguyen, Trang Anh; Ainslie, Philip N; Foster, Glen E

    2017-06-01

    What is the central question of this study? The aim was to determine, using the technique of agitated saline contrast echocardiography, whether exercise after 4-7 days at 5050 m would affect blood flow through intrapulmonary arteriovenous anastomoses (Q̇IPAVA) compared with exercise at sea level. What is the main finding and its importance? Despite a significant increase in both cardiac output and pulmonary pressure during exercise at high altitude, there is very little Q̇IPAVA at rest or during exercise after 4-7 days of acclimatization. Mathematical modelling suggests that bubble instability at high altitude is an unlikely explanation for the reduced Q̇IPAVA. Blood flow through intrapulmonary arteriovenous anastomoses (Q̇IPAVA) is elevated during exercise at sea level (SL) and at rest in acute normobaric hypoxia. After high altitude (HA) acclimatization, resting Q̇IPAVA is similar to that at SL, but it is unknown whether this is true during exercise at HA. We reasoned that exercise at HA (5050 m) would exacerbate Q̇IPAVA as a result of heightened pulmonary arterial pressure. Using a supine cycle ergometer, seven healthy adults free from intracardiac shunts underwent an incremental exercise test at SL [25, 50 and 75% of SL peak oxygen consumption (V̇O2 peak )] and at HA (25 and 50% of SL V̇O2 peak ). Echocardiography was used to determine cardiac output (Q̇) and pulmonary artery systolic pressure (PASP), and agitated saline contrast was used to determine Q̇IPAVA (bubble score; 0-5). The principal findings were as follows: (i) Q̇ was similar at SL rest (3.9 ± 0.47 l min -1 ) compared with HA rest (4.5 ± 0.49 l min -1 ; P = 0.382), but increased from rest during both SL and HA exercise (P exercise (P = 0.003); (iii) Q̇IPAVA was increased from SL rest (0) to HA rest (median = 1; P = 0.04) and increased from resting values during SL exercise (P exercise (P = 0.91), despite significant increases in Q̇ and PASP. Theoretical

  19. The Impact of Altitude on Sleep-Disordered Breathing in Children Dwelling at High Altitude: A Crossover Study.

    Science.gov (United States)

    Hughes, Benjamin H; Brinton, John T; Ingram, David G; Halbower, Ann C

    2017-09-01

    Sleep-disordered breathing (SDB) is prevalent among children and is associated with adverse health outcomes. Worldwide, approximately 250 million individuals reside at altitudes higher than 2000 meters above sea level (masl). The effect of chronic high-altitude exposure on children with SDB is unknown. This study aims to determine the impact of altitude on sleep study outcomes in children with SDB dwelling at high altitude. A single-center crossover study was performed to compare results of high-altitude home polysomnography (H-PSG) with lower altitude laboratory polysomnography (L-PSG) in school-age children dwelling at high altitude with symptoms consistent with SDB. The primary outcome was apnea-hypopnea index (AHI), with secondary outcomes including obstructive AHI; central AHI; and measures of oxygenation, sleep quality, and pulse rate. Twelve participants were enrolled, with 10 included in the final analysis. Median altitude was 1644 masl on L-PSG and 2531 masl on H-PSG. Median AHI was 2.40 on L-PSG and 10.95 on H-PSG. Both obstructive and central respiratory events accounted for the difference in AHI. Oxygenation and sleep fragmentation were worse and pulse rate higher on H-PSG compared to L-PSG. These findings reveal a clinically substantial impact of altitude on respiratory, sleep, and cardiovascular outcomes in children with SDB who dwell at high altitude. Within this population, L-PSG underestimates obstructive sleep apnea and central sleep apnea compared to H-PSG. Given the shortage of high-altitude pediatric sleep laboratories, these results suggest a role for home sleep apnea testing for children residing at high altitude. © Sleep Research Society 2017. Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.

  20. Reaching High Altitudes on Mars with an Inflatable Hypersonic Drag Balloon (Ballute)

    CERN Document Server

    Griebel, Hannes

    2010-01-01

    The concept of probing the atmosphere of planet Mars by means of a hypersonic drag balloon, a device known as a “ballute”, is a novel approach to planetary science. In this concept, the probe deploys an inflatable drag body out in space and may then enter the atmosphere either once or several times until it slowly descends towards the ground, taking continuous atmospheric and other readings across a large altitude and ground range. Hannes Griebel discusses the theory behind such a mission along with experience gained during its practical implementation, such as mission design, manufacturing, packing and deployment techniques as well as ground and flight tests. The author also studies other ballute applications, specifically emergency low Earth orbit recovery and delivering payloads to high altitude landing sites on Mars.

  1. High Altitude Platforms for Disaster Recovery: Capabilities, Strategies, and Techniques for Emergency Telecommunications

    Directory of Open Access Journals (Sweden)

    Deaton JuanD

    2008-01-01

    Full Text Available Abstract Natural disasters and terrorist acts have significant potential to disrupt emergency communication systems. These emergency communication networks include first-responder, cellular, landline, and emergency answering services such as 911, 112, or 999. Without these essential emergency communications capabilities, search, rescue, and recovery operations during a catastrophic event will be severely debilitated. High altitude platforms could be fitted with telecommunications equipment and used to support these critical communications missions once the catastrophic event occurs. With the ability to be continuously on station, HAPs provide excellent options for providing emergency coverage over high-risk areas before catastrophic incidents occur. HAPs could also provide enhanced 911 capabilities using either GPS or reference stations. This paper proposes potential emergency communications architecture and presents a method for estimating emergency communications systems traffic patterns for a catastrophic event.

  2. The Channel Estimation and Modeling in High Altitude Platform Station Wireless Communication Dynamic Network

    Directory of Open Access Journals (Sweden)

    Xiaoyang Liu

    2017-01-01

    Full Text Available In order to analyze the channel estimation performance of near space high altitude platform station (HAPS in wireless communication system, the structure and formation of HAPS are studied in this paper. The traditional Least Squares (LS channel estimation method and Singular Value Decomposition-Linear Minimum Mean-Squared (SVD-LMMS channel estimation method are compared and investigated. A novel channel estimation method and model are proposed. The channel estimation performance of HAPS is studied deeply. The simulation and theoretical analysis results show that the performance of the proposed method is better than the traditional methods. The lower Bit Error Rate (BER and higher Signal Noise Ratio (SNR can be obtained by the proposed method compared with the LS and SVD-LMMS methods.

  3. Provision of 3G Mobile Services in Sparsely Populated Areas Using High Altitude Platforms

    Directory of Open Access Journals (Sweden)

    J. Holis

    2008-04-01

    Full Text Available This paper deals with the application of High Altitude Platforms for the provision of third generation mobile services in sparsely-populated areas or in developing countries. It focuses on the behavior of large cells provided via a multiple HAP deployment and shows the possibilities of using small cells located inside these large cells to serve hot-spot areas. The impact of the different types of HAP antenna masks and their adjustment on cell capacity and the quality of coverage is presented. The main parameter of the antenna radiation pattern under investigation is the power roll-off at the cell edge. Optimal values of this parameter are presented for different scenarios. Simulations of system level parameters were based on an iteration loops approach.

  4. High Altitude Platforms for Disaster Recovery: Capabilities, Strategies, and Techniques for Emergency Telecommunications

    Directory of Open Access Journals (Sweden)

    Juan D. Deaton

    2008-09-01

    Full Text Available Natural disasters and terrorist acts have significant potential to disrupt emergency communication systems. These emergency communication networks include first-responder, cellular, landline, and emergency answering services such as 911, 112, or 999. Without these essential emergency communications capabilities, search, rescue, and recovery operations during a catastrophic event will be severely debilitated. High altitude platforms could be fitted with telecommunications equipment and used to support these critical communications missions once the catastrophic event occurs. With the ability to be continuously on station, HAPs provide excellent options for providing emergency coverage over high-risk areas before catastrophic incidents occur. HAPs could also provide enhanced 911 capabilities using either GPS or reference stations. This paper proposes potential emergency communications architecture and presents a method for estimating emergency communications systems traffic patterns for a catastrophic event.

  5. The Effect of Mutual Coupling on a High Altitude Platform Diversity System Using Compact Antenna Arrays

    Directory of Open Access Journals (Sweden)

    Tommy Hult

    2010-01-01

    Full Text Available We analyze the destructive effects of mutual coupling and spatial correlation between the separate antenna elements on a combined diversity system consisting of multiple HAPs (High-Altitude Platforms employing various compact MIMO (Multiple-Input Multiple-Output antenna array configurations, in order to enhance the mutual information in HAP communication links. In addition, we assess the influence of the separation angle between HAPs on system performance, and determine the optimal separation angles that maximize the total mutual information of the system for various compact MIMO antennas. Simulation results show that although the mutual information is degraded by mutual coupling and spatial correlation, the proposed HAP diversity system still provides better performance compared to a nondiversity system for all tested scenarios.

  6. Safe-site effects on rhizosphere bacterial communities in a high-altitude alpine environment.

    Science.gov (United States)

    Ciccazzo, Sonia; Esposito, Alfonso; Rolli, Eleonora; Zerbe, Stefan; Daffonchio, Daniele; Brusetti, Lorenzo

    2014-01-01

    The rhizosphere effect on bacterial communities associated with three floristic communities (RW, FI, and M sites) which differed for the developmental stages was studied in a high-altitude alpine ecosystem. RW site was an early developmental stage, FI was an intermediate stage, M was a later more matured stage. The N and C contents in the soils confirmed a different developmental stage with a kind of gradient from the unvegetated bare soil (BS) site through RW, FI up to M site. The floristic communities were composed of 21 pioneer plants belonging to 14 species. Automated ribosomal intergenic spacer analysis showed different bacterial genetic structures per each floristic consortium which differed also from the BS site. When plants of the same species occurred within the same site, almost all their bacterial communities clustered together exhibiting a plant species effect. Unifrac significance value (P floristic communities rhizospheres on their soil bacterial communities.

  7. Haematology and erythrocyte metabolism in man at high altitude: an Aymara-Quechua comparison.

    Science.gov (United States)

    Arnaud, J; Gutierrez, N; Tellez, W; Vergnes, H

    1985-07-01

    In the course of haematological and biological investigations among Aymara and Quechua populations in Bolivia, an anthropological study of the erythrocytary respiratory function was carried out on the two groups at two altitudes: 3,600 m and 450 m. A difference in the intensity of the biological variations of the two populations is observed at high altitude. In the Quechuas, as in any lowland native, the adaptative phenomena are totally and quickly reversible. In the Aymaras, we detected the existence of more marked haematological and biochemical characters: moderate polycythemia, hyperhaemoglobinemia, microcytosis, metabolical hyperactivity with accumulation of 2-3 di-phosphoglycerate and ATP, and methaemoglobinemia with a drop in the activity of the methaemoglobin reductases. The Aymaras preserve some of those characters (methaemoglobinemia excepted) when they settle in lowlands.

  8. Monitoring Mars LOD Variations from a High Altitude Circular Equatorial Orbit: Theory and Simulation

    Science.gov (United States)

    Barriot, J.; Dehant, V.; Duron, J.

    2003-12-01

    We compute the perturbations of a high altitude circular equatorial orbit of a martian probe under the influence of an annual variation of the martian lenght of day. For this purpose, we use the first order perturbations of the newtonian equations of motion, where the small parameter is given from the hourglass model of Chao and Rubincam, which allow a simple computation of CO2 exchanges during the martian year. We are able to demonstrate that the perturbations contains two components: the first one is a sine/cosine modulation at the orbit frequency, the second one is composed of terms of the form exp(t)*sin(t), so the orbit may not stable in the long term (several martian years), with perturbations growing exponentially. We give the full theory and numbers.

  9. Engineering assessment of in situ sulfate production onboard aircraft at high altitude

    Science.gov (United States)

    Smith, J.; Dykema, J. A.; Keith, D.

    2016-12-01

    Stratospheric injection of scattering aerosols has been proposed as a way to reduce global temperature increases by decreasing net atmospheric radiative forcing. Several methods have been suggested as a means of implementing solar geoengineering, and high altitude aircraft have been identified as an accessible means delivering sulfate aerosols to the lower and mid-stratosphere. This research initiative analyzes the design features of an onboard open cycle chemical plant capable of in situ sulfur to sulfate conversion, and compares the required mass to that of transporting pre-fabricated gaseous or liquid sulfate aerosol precursors. Scaling from aero-derivative gas turbine engines, commercial catalytic converters, and existing aerospace materials indicate that aircraft equipped with such a system could provide a substantial mass benefit compared to direct transport of compound sulfate products.

  10. Percutaneous closure of patent arterial ducts in patients from high altitude: a sub-Saharan experience

    Directory of Open Access Journals (Sweden)

    Endale Tefera

    2015-01-01

    Conclusions: Successful duct closure was achieved in the vast majority of patients, even though the ducts were larger and significant number of them had pulmonary hypertension in this high altitude group. There was a relatively higher incidence of residual shunts and device migration in this series, generally due to the nonavailability of optimal device and surgical support. Long-term follow-up is required before we can draw conclusions with regard to the sustainability of drop in PA pressures. Septal Occluder devices may be a possible alternative for large tubular or window-type ducts with severe pulmonary hypertension, where there may be concerns about the size and stability of duct occluder devices.

  11. High Altitude Platforms for Disaster Recovery: Capabilities, Strategies, and Techniques for Providing Emergency Telecommunications

    Energy Technology Data Exchange (ETDEWEB)

    Juan D. Deaton

    2008-05-01

    Natural disasters and terrorist acts have significant potential to disrupt emergency communication systems. These emergency communication networks include first-responder, cellular, landline, and emergency answering services such as 911, 112, or 999. Without these essential emergency communications capabilities, search, rescue, and recovery operations during a catastrophic event will be severely debilitated. High altitude platforms could be fitted with telecommunications equipment and used to support these critical communications missions once the catastrophic event occurs. With the ability to be continuously on station, HAPs provide excellent options for providing emergency coverage over high-risk areas before catastrophic incidents occur. HAPs could also provide enhanced 911 capabilities using either GPS or reference stations. This paper proposes potential emergency communications architecture and presents a method for estimating emergency communications systems traffic patterns for a catastrophic event.

  12. Modelling the future of the arctic sea ice cover

    OpenAIRE

    Myklebust, Erik Bryhn

    2017-01-01

    Record lows in sea ice cover have recently sparked new interest in the small ice cap instability. The change in albedo when sea ice becomes open water introduces a nonlinearity called the ice-albedo feedback. Forcing a joint energy- balance and sea ice model can lead to unstable ice caps in certain parameter regimes. When the ice caps are unstable, a small perturbation will initiate a tipping point in the sea ice cover. For tipping points in general, a number of studies have pointed out that ...

  13. Hypoxia triggers high-altitude headache with migraine features: A prospective trial.

    Science.gov (United States)

    Broessner, Gregor; Rohregger, Johanna; Wille, Maria; Lackner, Peter; Ndayisaba, Jean-Pierre; Burtscher, Martin

    2016-07-01

    Given the high prevalence and clinical impact of high-altitude headache (HAH), a better understanding of risk factors and headache characteristics may give new insights into the understanding of hypoxia being a trigger for HAH or even migraine attacks. In this prospective trial, we simulated high altitude (4500 m) by controlled normobaric hypoxia (FiO2 = 12.6%) to investigate acute mountain sickness (AMS) and headache characteristics. Clinical symptoms of AMS according to the Lake Louise Scoring system (LLS) were recorded before and after six and 12 hours in hypoxia. O2 saturation was measured using pulse oximetry at the respective time points. History of primary headache, especially episodic or chronic migraine, was a strict exclusion criterion. In total 77 volunteers (43 (55.8%) males, 34 (44.2%) females) were enrolled in this study. Sixty-three (81.18%) and 40 (71.4%) participants developed headache at six or 12 hours, respectively, with height and SpO2 being significantly different between headache groups at six hours (p headache development (p headache according to the International Classification of Headache Disorders (ICHD-3 beta) in n = 5 (8%) or n = 6 (15%), at six and 12 hours, respectively. Normobaric hypoxia is a trigger for HAH and migraine-like headache attacks even in healthy volunteers without any history of migraine. Our study confirms the pivotal role of hypoxia in the development of AMS and beyond that suggests hypoxia may be involved in migraine pathophysiology. © International Headache Society 2015.

  14. Establishment of extracorporeal circulation of artificial liver support system in high altitude region

    Directory of Open Access Journals (Sweden)

    Ming-sen ZHANG

    2011-01-01

    Full Text Available Objective To establish extracorporeal circulation in big animal suitable for the research on artificial liver support system in high altitude region.Methods Under the anesthesia of ketamine hydrochloride/diazepam IV,cannulation of common carotid artery/external jugular vein(n=3 and inferior vena cava via the left external jugular vein/right external jugular vein(n=3,was respectively performed on six healthy Chang-Bai piglets adapted to native environment(altitude 3700m.One day after that,the extracorporeal circulation was performed at a progressively elevated blood current velocity,and the general condition of the animals,blood pressure,HR,bleeding tendoncy of the experimental pigs and coagulation in the cannulae were observed.Results On the premise that the hemodynamics was not influenced,the highest blood current velocity was 133.33±28.87ml/min,the lowest heparin maintaining speed amounted to 138.67±12.22mg/h,and the bleeding tendency and blood coagulation in the cannula was significant in the group of common carotid artery/external jugular vein intubation.While the highest blood current velocity was 400ml/min,the lowest heparin maintaining speed was 26.67±9.24mg/h,no bleeding tendency or obvious cannular blood coagulation were observed in the group of cannulation of inferior vena cava via the left external jugular vein/right external jugular vein.These untoward results were significantly less or slight than that of the former group(P < 0.01.Conclusion It is suitable to perform research of artificial liver support system on piglets in high altitude region by establishing extracorporeal circulation by the way of inferior vena cava with cannulation passing through the left external jugular vein/right external jugular vein with the blood current velocity of 400ml/min.

  15. First Cluster results of the magnetic field structure of the mid- and high-altitude cusps

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    P. J. Cargill

    Full Text Available Magnetic field measurements from the four Cluster spacecraft from the mid- and high-altitude cusp are presented. Cluster underwent two encounters with the mid-altitude cusp during its commissioning phase (24 August 2000. Evidence for field-aligned currents (FACs was seen in the data from all three operating spacecraft from northern and southern cusps. The extent of the FACs was of the order of 1 RE in the X-direction, and at least 300 km in the Y-direction. However, fine-scale field structures with scales of the order of the spacecraft separation (300 km were observed within the FACs. In the northern crossing, two of the spacecraft appeared to lie along the same magnetic field line, and observed very well matched signals. However, the third spacecraft showed evidence for structuring transverse to the field on scales of a few hundred km. A crossing of the high-altitude cusp from 13 February 2001 is presented. It is revealed to be a highly dynamic structure with the boundaries moving with velocities ranging from a few km/s to tens of km/s, and having structure on timescales ranging from less than one minute up to several minutes. The cusp proper is associated with the presence of a very disordered magnetic field, which is entirely different from the magnetosheath turbulence.

    Key words. Magnetospheric physics (current systems; magnetopause, cusp, and boundary layers – Space plasma physics (discontinuities

  16. Serum irisin and myostatin levels after 2 weeks of high-altitude climbing.

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    Ewa Śliwicka

    Full Text Available Exposure to high-altitude hypoxia causes physiological and metabolic adaptive changes by disturbing homeostasis. Hypoxia-related changes in skeletal muscle affect the closely interconnected energy and regeneration processes. The balance between protein synthesis and degradation in the skeletal muscle is regulated by several molecules such as myostatin, cytokines, vitamin D, and irisin. This study investigates changes in irisin and myostatin levels in male climbers after a 2-week high-altitude expedition, and their association with 25(OHD and indices of inflammatory processes. The study was performed in 8 men aged between 23 and 31 years, who participated in a 2-week climbing expedition in the Alps. The measurements of body composition and serum concentrations of irisin, myostatin, 25(OHD, interleukin-6, myoglobin, high-sensitivity C-reactive protein, osteoprotegerin, and high-sensitivity soluble receptor activator of NF-κB ligand (sRANKL were performed before and after expedition. A 2-week exposure to hypobaric hypoxia caused significant decrease in body mass, body mass index (BMI, free fat mass and irisin, 25-Hydroxyvitamin D levels. On the other hand, significant increase in the levels of myoglobin, high-sensitivity C-reactive protein, interleukin-6, and osteoprotegerin were noted. The observed correlations of irisin with 25(OHD levels, as well as myostatin levels with inflammatory markers and the OPG/RANKL ratio indicate that these myokines may be involved in the energy-related processes and skeletal muscle regeneration in response to 2-week exposure to hypobaric hypoxia.

  17. Preventing High Altitude Cerebral Edema in Rats with Repurposed Anti-Angiogenesis Pharmacotherapy.

    Science.gov (United States)

    Tarshis, Samantha; Maltzahn, Joanne; Loomis, Zoe; Irwin, David C

    2016-12-01

    High altitude cerebral edema (HACE) is a fulminant, deadly, and yet still unpredictable brain disease. A new prophylactic treatment for HACE and its predecessor, acute mountain sickness (AMS), needs to be developed without the contraindications or adverse effect profiles of acetazolamide and dexamethasone. Since neovascularization signals are likely key contributors to HACE/AMS, our approach was to examine already existing anti-angiogenic drugs to inhibit potential initiating HACE pathway(s). This approach can also reveal crucial early steps in the frequently debated mechanism of HACE/AMS pathogenesis. We exposed four rat cohorts to hypobaric hypoxia and one to sea level (hyperbaric) conditions. The cohorts were treated with saline controls, an anti-angiogenesis drug (motesanib), a pro-angiogenesis drug (deferoxamine), or an intraperitoneal version of the established AMS prophylaxis drug, acetazolamide (benzolamide). Brain tissue was analyzed for cerebrovascular leak using the Evans Blue Dye (EVBD) protocol. We observed significantly increased EVBD in the altitude control and pro-angiogenesis (deferoxamine) cohorts, and significantly decreased EVBD in the anti-angiogenesis (motesanib), established treatment (benzolamide), and sea-level cohorts. Anti-angiogenesis-treated cohorts demonstrated less cerebrovascular extravasation than the altitude control and pro-angiogenesis treated rats, suggesting promise as an alternative prophylactic HACE/AMS treatment. The leak exacerbation with pro-angiogenesis treatment and improvement with anti-angiogenesis treatment support the hypothesis of early neovascularization signals provoking HACE. We demonstrate statistically significant evidence to guide further investigation for VEGF- and HIF-inhibitors as HACE/AMS prophylaxis, and as elucidators of still unknown HACE pathogenesis.Tarshis S, Maltzahn J, Loomis Z, Irwin DC. Preventing high altitude cerebral edema in rats with repurposed anti-angiogenesis pharmacotherapy. Aerosp Med

  18. Elevated plasma cholecystokinin at high altitude: metabolic implications for the anorexia of acute mountain sickness.

    Science.gov (United States)

    Bailey, D M; Davies, B; Milledge, J S; Richards, M; Williams, S R; Jordinson, M; Calam, J

    2000-01-01

    The aims of the present study were to measure the satiety neuropeptide cholecystokinin (CCK) in humans at terrestrial high altitude to investigate its possible role in the pathophysiology of anorexia, cachexia, and acute mountain sickness (AMS). Nineteen male mountaineers aged 38 +/- 12 years participated in a 20 +/- 5 day trek to Mt. Kanchenjunga basecamp (BC) located at 5,100 m, where they remained for 7 +/- 5 days. Subjects were examined at rest and during a maximal exercise test at sea-level before/after the expedition (SL1/SL2) and during the BC sojourn. There was a mild increase in Lake Louise AMS score from 1.1 +/- 1.2 points at SL1 to 2.3 +/- 2.3 points by the end of the first day at BC (P anorexia on Day 2 compared with those with a normal appetite. While there was no relationship between the increase in CCK and AMS score at BC, a more pronounced increase in resting CCK was observed in subjects with AMS (> or =3 points at the end of Day 1 at BC) compared with those without (+98.9 +/- 1.4 pmol/L(-1) vs. +67.6 +/- 37.2 pmol/L(-1), P < 0.05). Caloric intake remained remarkably low during the stay at BC (8.9 +/- 1.4 MJ.d(-1)) despite a progressive decrease in total body mass (-4.5 +/- 2.1 kg after 31 +/- 13 h at BC, P < 0.05 vs. SL1/SL2), which appeared to be due to a selective loss of torso adipose tissue. These findings suggest that the satiogenic effects of CCK may have contributed to the observed caloric deficit and subsequent cachexia at high altitude despite adequate availability of palatable foods. The metabolic implications of elevated CCK in AMS remain to be elucidated.

  19. Positive Association of D Allele of ACE Gene With High Altitude Pulmonary Edema in Indian Population.

    Science.gov (United States)

    Bhagi, Shuchi; Srivastava, Swati; Tomar, Arvind; Bala Singh, Shashi; Sarkar, Soma

    2015-06-01

    High altitude pulmonary edema (HAPE) is a potentially fatal high altitude illness occurring as a result of hypobaric hypoxia with an unknown underlying genetic mechanism. Recent studies have shown a possible association between HAPE and polymorphisms in genes of the renin-angiotensin-aldosterone system (RAAS), which play a key role in sensitivity of an individual toward HAPE. For the present investigation, study groups consisted of HAPE patients (HAPE) and acclimatized control subjects (rCON). Four single-nucleotide polymorphisms (SNPs) were genotyped using restriction fragment length polymorphism (RFLP) analysis in genes of the RAAS pathway, specifically, renin (REN) C(-4063)T (rs41317140) and RENi8-83 (rs2368564), angiotensin (AGT) M(235)T (rs699), and angiotensin-converting enzyme (ACE) insertion/deletion (I/D) (rs1799752). Only the I/D polymorphism of the ACE gene showed a significant difference between the HAPE and rCON groups. The frequency of the D allele was found to be significantly higher in the HAPE group. Arterial oxygen saturation levels were significantly lower in the HAPE group compared with the rCON group and also decreased in the I/D and D/D genotypes compared with the I/I genotype in these groups. The other polymorphisms occurring in the REN and AGT genes were not significantly different between the 2 groups. These findings demonstrate a possible association of the I/D polymorphism of the ACE gene with the development of HAPE, with D/D being the at-risk genotype. Copyright © 2015 Wilderness Medical Society. Published by Elsevier Inc. All rights reserved.

  20. An appraisal of precipitation distribution in the high-altitude catchments of the Indus basin.

    Science.gov (United States)

    Dahri, Zakir Hussain; Ludwig, Fulco; Moors, Eddy; Ahmad, Bashir; Khan, Asif; Kabat, Pavel

    2016-04-01

    Scarcity of in-situ observations coupled with high orographic influences has prevented a comprehensive assessment of precipitation distribution in the high-altitude catchments of Indus basin. Available data are generally fragmented and scattered with different organizations and mostly cover the valleys. Here, we combine most of the available station data with the indirect precipitation estimates at the accumulation zones of major glaciers to analyse altitudinal dependency of precipitation in the high-altitude Indus basin. The available observations signified the importance of orography in each sub-hydrological basin but could not infer an accurate distribution of precipitation with altitude. We used Kriging with External Drift (KED) interpolation scheme with elevation as a predictor to appraise spatiotemporal distribution of mean monthly, seasonal and annual precipitation for the period of 1998-2012. The KED-based annual precipitation estimates are verified by the corresponding basin-wide observed specific runoffs, which show good agreement. In contrast to earlier studies, our estimates reveal substantially higher precipitation in most of the sub-basins indicating two distinct rainfall maxima; 1st along southern and lower most slopes of Chenab, Jhelum, Indus main and Swat basins, and 2nd around north-west corner of Shyok basin in the central Karakoram. The study demonstrated that the selected gridded precipitation products covering this region are prone to significant errors. In terms of quantitative estimates, ERA-Interim is relatively close to the observations followed by WFDEI and TRMM, while APHRODITE gives highly underestimated precipitation estimates in the study area. Basin-wide seasonal and annual correction factors introduced for each gridded dataset can be useful for lumped hydrological modelling studies, while the estimated precipitation distribution can serve as a basis for bias correction of any gridded precipitation products for the study area

  1. Propagation and Breaking at High Altitudes of Gravity Waves Excited by Tropospheric Forcing

    Science.gov (United States)

    Prusa, Joseph M.; Smolarkiewicz, Piotr K.; Garcia, Rolando R.

    1996-01-01

    An anelastic approximation is used with a time-variable coordinate transformation to formulate a two-dimensional numerical model that describes the evolution of gravity waves. The model is solved using a semi-Lagrangian method with monotone (nonoscillatory) interpolation of all advected fields. The time-variable transformation is used to generate disturbances at the lower boundary that approximate the effect of a traveling line of thunderstorms (a squall line) or of flow over a broad topographic obstacle. The vertical propagation and breaking of the gravity wave field (under conditions typical of summer solstice) is illustrated for each of these cases. It is shown that the wave field at high altitudes is dominated by a single horizontal wavelength; which is not always related simply to the horizontal dimension of the source. The morphology of wave breaking depends on the horizontal wavelength; for sufficiently short waves, breaking involves roughly one half of the wavelength. In common with other studies, it is found that the breaking waves undergo "self-acceleration," such that the zonal-mean intrinsic frequency remains approximately constant in spite of large changes in the background wind. It is also shown that many of the features obtained in the calculations can be understood in terms of linear wave theory. In particular, linear theory provides insights into the wavelength of the waves that break at high altitudes, the onset and evolution of breaking. the horizontal extent of the breaking region and its position relative to the forcing, and the minimum and maximum altitudes where breaking occurs. Wave breaking ceases at the altitude where the background dissipation rate (which in our model is a proxy for molecular diffusion) becomes greater than the rate of dissipation due to wave breaking, This altitude, in effect, the model turbopause, is shown to depend on a relatively small number of parameters that characterize the waves and the background state.

  2. Serum irisin and myostatin levels after 2 weeks of high-altitude climbing.

    Science.gov (United States)

    Śliwicka, Ewa; Cisoń, Tomasz; Kasprzak, Zbigniew; Nowak, Alicja; Pilaczyńska-Szcześniak, Łucja

    2017-01-01

    Exposure to high-altitude hypoxia causes physiological and metabolic adaptive changes by disturbing homeostasis. Hypoxia-related changes in skeletal muscle affect the closely interconnected energy and regeneration processes. The balance between protein synthesis and degradation in the skeletal muscle is regulated by several molecules such as myostatin, cytokines, vitamin D, and irisin. This study investigates changes in irisin and myostatin levels in male climbers after a 2-week high-altitude expedition, and their association with 25(OH)D and indices of inflammatory processes. The study was performed in 8 men aged between 23 and 31 years, who participated in a 2-week climbing expedition in the Alps. The measurements of body composition and serum concentrations of irisin, myostatin, 25(OH)D, interleukin-6, myoglobin, high-sensitivity C-reactive protein, osteoprotegerin, and high-sensitivity soluble receptor activator of NF-κB ligand (sRANKL) were performed before and after expedition. A 2-week exposure to hypobaric hypoxia caused significant decrease in body mass, body mass index (BMI), free fat mass and irisin, 25-Hydroxyvitamin D levels. On the other hand, significant increase in the levels of myoglobin, high-sensitivity C-reactive protein, interleukin-6, and osteoprotegerin were noted. The observed correlations of irisin with 25(OH)D levels, as well as myostatin levels with inflammatory markers and the OPG/RANKL ratio indicate that these myokines may be involved in the energy-related processes and skeletal muscle regeneration in response to 2-week exposure to hypobaric hypoxia.

  3. Cerebrovascular reactivity among native-raised high altitude residents: an fMRI study

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    Zhang Jiaxing

    2011-09-01

    Full Text Available Abstract Background The impact of long term residence on high altitude (HA on human brain has raised concern among researchers in recent years. This study investigated the cerebrovascular reactivity among native-born high altitude (HA residents as compared to native sea level (SL residents. The two groups were matched on the ancestral line, ages, gender ratios, and education levels. A visual cue guided maximum inspiration task with brief breath holding was performed by all the subjects while Blood-Oxygenation-Level-Dependent (BOLD functional Magnetic Resonance Imaging (fMRI data were acquired from them. Results Compared to SL controls, the HA group showed generally decreased cerebrovascular reactivity and longer delay in hemodynamic response. Clusters showing significant differences in the former aspect were located at the bilateral primary motor cortex, the right somatosensory association cortex, the right thalamus and the right caudate, the bilateral precuneus, the right cingulate gyrus and the right posterior cingulate cortex, as well as the left fusiform gyrus and the right lingual cortex; clusters showing significant differences in the latter aspect were located at the precuneus, the insula, the superior frontal and temporal gyrus, the somatosensory cortex (the postcentral gyrus and the cerebellar tonsil. Inspiratory reserve volume (IRV, which is an important aspect of pulmonary function, demonstrated significant correlation with the amount of BOLD signal change in multiple brain regions, particularly at the bilateral insula among the HA group. Conclusions Native-born HA residents generally showed reduced cerebrovascular reactivity as demonstrated in the hemodynamic response during a visual cue guided maximum inspiration task conducted with BOLD-fMRI. This effect was particularly manifested among brain regions that are typically involved in cerebral modulation of respiration.

  4. Perinatal hypoxia increases susceptibility to high-altitude polycythemia and attendant pulmonary vascular dysfunction.

    Science.gov (United States)

    Julian, Colleen Glyde; Gonzales, Marcelino; Rodriguez, Armando; Bellido, Diva; Salmon, Carlos Salinas; Ladenburger, Anne; Reardon, Lindsay; Vargas, Enrique; Moore, Lorna G

    2015-08-15

    Perinatal exposures exert a profound influence on physiological function, including developmental processes vital for efficient pulmonary gas transfer throughout the lifespan. We extend the concept of developmental programming to chronic mountain sickness (CMS), a debilitating syndrome marked by polycythemia, ventilatory impairment, and pulmonary hypertension that affects ∼10% of male high-altitude residents. We hypothesized that adverse perinatal oxygenation caused abnormalities of ventilatory and/or pulmonary vascular function that increased susceptibility to CMS in adulthood. Subjects were 67 male high-altitude (3,600-4,100 m) residents aged 18-25 yr with excessive erythrocytosis (EE, Hb concentration ≥18.3 g/dl), a preclinical form of CMS, and 66 controls identified from a community-based survey (n = 981). EE subjects not only had higher Hb concentrations and erythrocyte counts, but also lower alveolar ventilation, impaired pulmonary diffusion capacity, higher systolic pulmonary artery pressure, lower pulmonary artery acceleration time, and more frequent right ventricular hypertrophy, than controls. Compared with controls, EE subjects were more often born to mothers experiencing hypertensive complications of pregnancy and hypoxia during the perinatal period, with each increasing the risk of developing EE (odds ratio = 5.25, P = 0.05 and odds ratio = 6.44, P = 0.04, respectively) after other factors known to influence EE status were taken into account. Adverse perinatal oxygenation is associated with increased susceptibility to EE accompanied by modest abnormalities of the pulmonary circulation that are independent of increased blood viscosity. The association between perinatal hypoxia and EE may be due to disrupted alveolarization and microvascular development, leading to impaired gas exchange and/or pulmonary hypertension. Copyright © 2015 the American Physiological Society.

  5. Manipulating API and AOD data to distinguish transportation of aerosol at high altitude in Penang, Malaysia

    International Nuclear Information System (INIS)

    Tan, F; Lim, H S; Abdullah, K; Yoon, T L; Matjafri, M Z; Holben, B

    2014-01-01

    Air pollution index (API) is an index commonly used in Malaysia to determine the air quality level. It is a ground truth data measurement which is unable to unambiguously quantify air quality level at higher atmosphere. On the other hand, aerosol optical depth (AOD) from AERONET data obtained using sun photometer provides reading of the air quality for a column of atmosphere from ground surface. We first determine the quantitative correlation between the API and AOD data collected in Penang, Malaysia, between January – September, 2012, using two independent methods, one based on regression analysis and the other interpolation. Our purpose is to establish a systematic numerical procedure to determine whether aerosol transported in high altitude from other location has occurred. Two independent methods for establishing the quantitative relationship between the API and AOD data were used as a way to facilitate the verification of our approach. In our method, data from southwest monsoon period (August to September) were used as ''calibration dataset'' to establish the quantitative correlation between the AOD and API data. The established calibrated coefficients is then used to predict the AOD of other months, which are then compared against the data actually measured. Discrepancy between the predicted and measured AOD data can then be interpreted as an indication of whether the atmosphere at high altitude is polluted by aerosol transported from other location. If the predicted AOD is much larger than that measured, back trajectory analysis was applied to identify the aerosol transported source. This procedure is very helpful to investigate the aerosol transportation and distribution patterns during monsoon and non monsoon periods

  6. PHYTOCHEMICAL AND PROTEOMIC ANALYSIS OF A HIGH ALTITUDE MEDICINAL MUSHROOM CORDYCEPS SINENSIS

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    Rakhee

    2016-09-01

    Full Text Available Cordyceps sinensis (C. sinensis is well established as a traditional Chinese medicine (TCM that has been valued as a health food for centuries. It is an entomopathogenic fungus in Ascomycetes that naturally occurs at high altitude in Himalayan region and has received considerable attention due to the abundance of various biologically active compounds. Despite having reported health benefits and economic importance, qualitative phytochemical analysis, proximate composition and proteome study of Indian isolates of C. sinensis grown at high altitude remains untapped. In the present study, qualitative phytochemical analysis was carried on powdered whole body of C. sinensis (CSWb and its aqueous extract (CSAq prepared by accelerated solvent extraction technique which indicated the presence of several bioactive constituents such as alkaloids, amino acids and proteins, carbohydrates, flavonoids and phenols, gums, mucilages and saponins. We evaluated chemical composition of the Indian Himalayan medicinal mushroom C. sinensis in terms of its carbohydrate (55.68% content, crude fiber (6.40%, fat (1.80%, moisture (7.18%, protein (21.46% and total ash (7.48%. Furthermore, soluble protein identification of both CSWb and CSAq by SDS-PAGE followed by MALDI-TOF-TOF analysis revealed the presence of various types of most abundant proteins such as P-type II A ATPase, TE1b [Blumeriagraminis f. sp. hordei], Chitin synthase Chs [Penicilliummarneffei ATCC 18224], Serine/threonine-protein kinase CLA4, DEHA2C06820p [Debaryomyceshansenii CBS767], YALI0E29887p [Yarrowialipolytica] etc. In conclusion, the present study provides a comprehensive qualitative phytochemical analysis, proximate composition and proteome study on Indian isolate of C. sinensis which could endorse its use as a functional food.

  7. Evolved changes in the intracellular distribution and physiology of muscle mitochondria in high-altitude native deer mice.

    Science.gov (United States)

    Mahalingam, Sajeni; McClelland, Grant B; Scott, Graham R

    2017-07-15

    Mitochondrial function changes over time at high altitudes, but the potential benefits of these changes for hypoxia resistance remains unclear. We used high-altitude-adapted populations of deer mice, which exhibit enhanced aerobic performance in hypoxia, to examine whether changes in mitochondrial physiology or intracellular distribution in the muscle contribute to hypoxia resistance. Permeabilized muscle fibres from the gastrocnemius muscle had higher respiratory capacities in high-altitude mice than in low-altitude mice. Highlanders also had higher mitochondrial volume densities, due entirely to an enriched abundance of subsarcolemmal mitochondria, such that more mitochondria were situated near the cell membrane and adjacent to capillaries. There were several effects of hypoxia acclimation on mitochondrial function, some of which were population specific, but they differed from the evolved changes in high-altitude natives, which probably provide a better indication of adaptive traits that improve performance and hypoxia resistance at high altitudes. High-altitude natives that have evolved to live in hypoxic environments provide a compelling system to understand how animals can overcome impairments in oxygen availability. We examined whether these include changes in mitochondrial physiology or intracellular distribution that contribute to hypoxia resistance in high-altitude deer mice (Peromyscus maniculatus). Mice from populations native to high and low altitudes were born and raised in captivity, and as adults were acclimated to normoxia or hypobaric hypoxia (equivalent to 4300 m elevation). We found that highlanders had higher respiratory capacities in the gastrocnemius (but not soleus) muscle than lowlanders (assessed using permeabilized fibres with single or multiple inputs to the electron transport system), due in large part to higher mitochondrial volume densities in the gastrocnemius. The latter was attributed to an increased abundance of subsarcolemmal

  8. Apical cap

    International Nuclear Information System (INIS)

    McLoud, T.C.; Isler, R.J.; Novelline, R.A.; Putman, C.E.; Simeone, J.; Stark, P.

    1981-01-01

    Apical caps, either unilateral or bilateral, are a common feature of advancing age and are usually the result of subpleural scarring unassociated with other diseases. Pancoast (superior sulcus) tumors are a well recognized cause of unilateral asymmetric apical density. Other lesions arising in the lung, pleura, or extrapleural space may produce unilateral or bilateral apical caps. These include: (1) inflammatory: tuberculosis and extrapleural abscesses extending from the neck; (2) post radiation fibrosis after mantle therapy for Hodgkin disease or supraclavicular radiation in the treatment of breast carcinoma; (3) neoplasm: lymphoma extending from the neck or mediastinum, superior sulcus bronchogenic carcinoma, and metastases; (4) traumatic: extrapleural dissection of blood from a ruptured aorta, fractures of the ribs or spine, or hemorrhage due to subclavian line placement; (5) vascular: coarctation of the aorta with dilated collaterals over the apex, fistula between the subclavian artery and vein; and (6) miscellaneous: mediastinal lipomatosis with subcostal fat extending over the apices

  9. Recently deglaciated high-altitude soils of the Himalaya: diverse environments, heterogenous bacterial communities and long-range dust inputs from the upper troposphere.

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    Blaz Stres

    Full Text Available The Himalaya with its altitude and geographical position forms a barrier to atmospheric transport, which produces much aqueous-particle monsoon precipitation and makes it the largest continuous ice-covered area outside polar regions. There is a paucity of data on high-altitude microbial communities, their native environments and responses to environmental-spatial variables relative to seasonal and deglaciation events.Soils were sampled along altitude transects from 5000 m to 6000 m to determine environmental, spatial and seasonal factors structuring bacterial communities characterized by 16 S rRNA gene deep sequencing. Dust traps and fresh-snow samples were used to assess dust abundance and viability, community structure and abundance of dust associated microbial communities. Significantly different habitats among the altitude-transect samples corresponded to both phylogenetically distant and closely-related communities at distances as short as 50 m showing high community spatial divergence. High within-group variability that was related to an order of magnitude higher dust deposition obscured seasonal and temporal rearrangements in microbial communities. Although dust particle and associated cell deposition rates were highly correlated, seasonal dust communities of bacteria were distinct and differed significantly from recipient soil communities. Analysis of closest relatives to dust OTUs, HYSPLIT back-calculation of airmass trajectories and small dust particle size (4-12 µm suggested that the deposited dust and microbes came from distant continental, lacustrine and marine sources, e.g. Sahara, India, Caspian Sea and Tibetan plateau. Cyanobacteria represented less than 0.5% of microbial communities suggesting that the microbial communities benefitted from (codeposited carbon which was reflected in the psychrotolerant nature of dust-particle associated bacteria.The spatial, environmental and temporal complexity of the high-altitude soils of the

  10. Recently deglaciated high-altitude soils of the Himalaya: diverse environments, heterogenous bacterial communities and long-range dust inputs from the upper troposphere.

    Science.gov (United States)

    Stres, Blaz; Sul, Woo Jun; Murovec, Bostjan; Tiedje, James M

    2013-01-01

    The Himalaya with its altitude and geographical position forms a barrier to atmospheric transport, which produces much aqueous-particle monsoon precipitation and makes it the largest continuous ice-covered area outside polar regions. There is a paucity of data on high-altitude microbial communities, their native environments and responses to environmental-spatial variables relative to seasonal and deglaciation events. Soils were sampled along altitude transects from 5000 m to 6000 m to determine environmental, spatial and seasonal factors structuring bacterial communities characterized by 16 S rRNA gene deep sequencing. Dust traps and fresh-snow samples were used to assess dust abundance and viability, community structure and abundance of dust associated microbial communities. Significantly different habitats among the altitude-transect samples corresponded to both phylogenetically distant and closely-related communities at distances as short as 50 m showing high community spatial divergence. High within-group variability that was related to an order of magnitude higher dust deposition obscured seasonal and temporal rearrangements in microbial communities. Although dust particle and associated cell deposition rates were highly correlated, seasonal dust communities of bacteria were distinct and differed significantly from recipient soil communities. Analysis of closest relatives to dust OTUs, HYSPLIT back-calculation of airmass trajectories and small dust particle size (4-12 µm) suggested that the deposited dust and microbes came from distant continental, lacustrine and marine sources, e.g. Sahara, India, Caspian Sea and Tibetan plateau. Cyanobacteria represented less than 0.5% of microbial communities suggesting that the microbial communities benefitted from (co)deposited carbon which was reflected in the psychrotolerant nature of dust-particle associated bacteria. The spatial, environmental and temporal complexity of the high-altitude soils of the Himalaya

  11. Imaging Findings of a Survivor of Avalanche without Any Life Support at Very High Altitude and Extreme Low Temperatures

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    Abhishek Dwivedi

    2016-10-01

    Full Text Available Survival at high altitude is very challenging and in spite of adequate training and acclimatization, injuries are frequent. The fate of mountaineers and soldiers at such areas largely depends on the mercy of the climate. An avalanche causes physical trauma, cold injury and asphyxia to the victim. The patient in our report had diffuse cerebral edema, bilateral pulmonary consolidation and pneumothorax. In spite of the best efforts the victim succumbed to the injuries. There are many incidents of high altitude accidents in India. This case report is of a soldier deployed at the high altitude, is a lone ever reported survivor above 5000 meters, under 35 feet snow and below - 45°C for greater than 5 days of exposure to an avalanche

  12. Short-term adaptation and chronic cardiac remodelling to high altitude in lowlander natives and Himalayan Sherpa.

    Science.gov (United States)

    Stembridge, Mike; Ainslie, Philip N; Shave, Rob

    2015-11-01

    What is the topic of this review? At high altitude, the cardiovascular system must adapt in order to meet the metabolic demand for oxygen. This review summarizes recent findings relating to short-term and life-long cardiac adaptation to high altitude in the context of exercise capacity. What advances does it highlight? Both Sherpa and lowlanders exhibit smaller left ventricular volumes at high altitude; however, myocardial relaxation, as evidenced by diastolic untwist, is reduced only in Sherpa, indicating that short-term hypoxia does not impair diastolic relaxation. Potential remodelling of systolic function, as evidenced by lower left ventricular systolic twist in Sherpa, may facilitate the requisite sea-level mechanical reserve required during exercise, although this remains to be confirmed. Both short-term and life-long high-altitude exposure challenge the cardiovascular system to meet the metabolic demand for O2 in a hypoxic environment. As the demand for O2 delivery increases during exercise, the circulatory component of oxygen transport is placed under additional stress. Acute adaptation and chronic remodelling of cardiac structure and function may occur to facilitate O2 delivery in lowlanders during sojourn to high altitude and in permanent highland residents. However, our understanding of cardiac structural and functional adaption in Sherpa remains confined to a higher maximal heart rate, lower pulmonary vascular resistance and no differences in resting cardiac output. Ventricular form and function are intrinsically linked through the left ventricular (LV) mechanics that facilitate efficient ejection, minimize myofibre stress during contraction and aid diastolic recoil. Recent examination of LV mechanics has allowed detailed insight into fundamental cardiac adaptation in high-altitude Sherpa. In this symposium report, we review recent advances in our understanding of LV function in both lowlanders and Sherpa at rest and discuss the potential consequences

  13. Endothelial dysfunction assessment by flow-mediated dilation in a high-altitude population.

    Science.gov (United States)

    Calderón-Gerstein, Walter S; López-Peña, Antonio; Macha-Ramírez, Raúl; Bruno-Huamán, Astrid; Espejo-Ramos, Roxana; Vílchez-Bravo, Stephany; Ramírez-Breña, María; Damián-Mucha, Milagros; Matos-Mucha, Adriana

    2017-01-01

    Endothelial function at high altitude has been measured only in populations that are genetically adapted to chronic hypoxia. The objective of this study was to evaluate endothelial dysfunction (ED) in a nongenetically adapted high-altitude population of the Andes mountains, in Huancayo, Peru (3,250 meters above sea level). Participants included 61 patients: 28 cases and 33 controls. The cases were subjects with hypertension, diabetes mellitus, obesity, or a history of stroke or coronary artery disease. Flow-mediated vasodilation (FMD) of the brachial artery was measured in the supine position, at noon, after 5 minutes of resting. The brachial artery was identified above the elbow. Its basal diameter was measured during diastole, and FMD was tested after 5 minutes of forearm ischemia. Intima-media complex in the right carotid artery was also determined. An increase in the artery's baseline diameter diabetics had ED; ED was also found in 68.8% of obese individuals, 55% of hypertensive patients, and 46.5% of controls. Age, height, body mass index, and waist diameter were higher in the cases as compared with the controls. A total of 57.9% (n=11) of the cases and 45.2% (n=19) of the controls presented ED. Patients without ED had a mean increase in brachial artery diameter of 23.16%, while in those with ED it was only 3.84%. Individuals with diabetes or hypertension had a greater thickness of the carotid artery intima media layer (1.092 versus 0.664 cm) ( p =0.037). A positive test for ED was associated with a greater basal diameter of the brachial artery (4.66±0.62 versus 4.23±0.59 cm) ( p =0.02). A total of 7 patients presented paradoxical response, developing posthyperemia vasoconstriction. The proportion of ED was high among controls and among patients with risk factors. Controls showed better FMD profiles than subjects studied in Tibet and the Himalayas.

  14. Impact of high altitude on the hepatic fatty acid oxidation and synthesis in rats

    Energy Technology Data Exchange (ETDEWEB)

    Ni, Qian [Department of General Surgery, Hepatic-biliary-pancreatic Institute, Lanzhou University Second Hospital, Lanzhou (China); Department of Pediatrics, Lanzhou University Second Hospital, Lanzhou (China); Shao, Yuan; Wang, Ying Zhen [Department of General Surgery, Hepatic-biliary-pancreatic Institute, Lanzhou University Second Hospital, Lanzhou (China); Jing, Yu Hong [Institute of Anatomy, School of Basic Medicine, Lanzhou University, Lanzhou (China); Zhang, You Cheng, E-mail: zhangychmd@126.com [Department of General Surgery, Hepatic-biliary-pancreatic Institute, Lanzhou University Second Hospital, Lanzhou (China)

    2014-04-04

    Highlights: • Acute exposure to high altitude (HA) increased hepatic fatty acid (FA) β-oxidation. • Acute exposure of rats to HA increased hepatic FA synthesis. • PPARα and AMPK can regulate the FA metabolism. • FA may be a key energy fuel and a compensation for CHO during acute exposure to HA. • The acute changes of FA metabolism may be a mechanism of acclimatization. - Abstract: High altitude (HA) affects energy metabolism. The impact of acute and chronic HA acclimatization on the major metabolic pathways is still controversial. In this study, we aimed to unveil the impact of HA on the key enzymes involved in the fatty acid (FA) metabolism in liver. Rats were exposed to an altitude of 4300 m for 30 days and the expressions of two key proteins involved in FA β-oxidation (carnitine palmitoyl transferase I, CPT-I; and peroxisome proliferator-activated receptor alpha, PPARα), two proteins involved in FA synthesis (acetyl CoA carboxylase-1, ACC-1; and AMP-activated protein kinase, AMPK), as well as the total ketone body in the liver and the plasma FFAs were examined. Rats without HA exposure were used as controls. We observed that the acute exposure of rats to HA (3 days) led to a significant increase in the expressions of CPT-I and PPARα and in the total hepatic ketone body. Longer exposure (15 days) caused a marked decrease in the expression of CPT-I and PPARα. By 30 days after HA exposure, the expression levels of CPT-I and PPARα returned to the control level. The hepatic ACC-1 level showed a significant increase in rats exposed to HA for 1 and 3 days. In contrast, the hepatic level of AMPK showed a significant reduction throughout the experimental period. Plasma FFA concentrations did not show any significant changes following HA exposure. Thus, increased hepatic FA oxidation and synthesis in the early phase of HA exposure may be among the important mechanisms for the rats to respond to the hypoxic stress in order to acclimatize themselves to the

  15. Development of a Compact High Altitude Imager and Sounding Radiometer (CHAISR)

    Science.gov (United States)

    Choi, R. K. Y.; Min, S.; Cho, Y. J.; Kim, K. H.; Ha, J. C.; Joo, S. W.

    2017-12-01

    Joint Civilian-Military Committee, under Advisory Council on Science and Technology, Korea, has approved a technology demonstration project for developing a lightweight HALE UAV (High-Altitude, Long Endurance). It aims to operate at lower stratosphere, i.e. altitude of 16 20 km, offering unique observational platform to atmospheric research community as pseudo-satellite. NIMS (National Institute of Meteorological Sciences, Korea) is responsible for a payload for atmospheric science, a Compact High Altitude Imager and Sounding Radiometer (CHAISR) to demonstrate scientific observations at lower stratosphere in the interest of improving numerical weather prediction model. CHAISR consists of three microwave radiometers (MWR) with 16 channel, and medium resolution cameras operating in a visible and infrared spectrum. One of the technological challenges for CHAISR is to accommodate those instruments within 50 W of power consumption. CHAISR will experience temperature up to -75°C, while pressure as low as 50 hPa at operational altitude. It requires passive thermal control of the payload to keep electronic subsystems warm enough for instrument operation with minimal power available. Safety features, such as payload power management and thermal control, are considered with minimal user input. Three radiometers measure atmospheric brightness temperature at frequency at around 20, 40, and 50 GHz. Retrieval process yields temperature and humidity profiles with cross track scan along the flight line. Estimated total weight of all radiometer hardware, from the antennas to data acquisition system, is less than 0.8 kg and a maximum power consumption is 15.2 W. With not enough power for blackbody calibration target, radiometers use zenith sky view at lower stratosphere as an excellent calibration target for a conventional tipping-curve calibration. Spatial distributions of clouds from visible and surface temperature from thermal cameras are used as additional information for

  16. Impact of high altitude on the hepatic fatty acid oxidation and synthesis in rats

    International Nuclear Information System (INIS)

    Ni, Qian; Shao, Yuan; Wang, Ying Zhen; Jing, Yu Hong; Zhang, You Cheng

    2014-01-01

    Highlights: • Acute exposure to high altitude (HA) increased hepatic fatty acid (FA) β-oxidation. • Acute exposure of rats to HA increased hepatic FA synthesis. • PPARα and AMPK can regulate the FA metabolism. • FA may be a key energy fuel and a compensation for CHO during acute exposure to HA. • The acute changes of FA metabolism may be a mechanism of acclimatization. - Abstract: High altitude (HA) affects energy metabolism. The impact of acute and chronic HA acclimatization on the major metabolic pathways is still controversial. In this study, we aimed to unveil the impact of HA on the key enzymes involved in the fatty acid (FA) metabolism in liver. Rats were exposed to an altitude of 4300 m for 30 days and the expressions of two key proteins involved in FA β-oxidation (carnitine palmitoyl transferase I, CPT-I; and peroxisome proliferator-activated receptor alpha, PPARα), two proteins involved in FA synthesis (acetyl CoA carboxylase-1, ACC-1; and AMP-activated protein kinase, AMPK), as well as the total ketone body in the liver and the plasma FFAs were examined. Rats without HA exposure were used as controls. We observed that the acute exposure of rats to HA (3 days) led to a significant increase in the expressions of CPT-I and PPARα and in the total hepatic ketone body. Longer exposure (15 days) caused a marked decrease in the expression of CPT-I and PPARα. By 30 days after HA exposure, the expression levels of CPT-I and PPARα returned to the control level. The hepatic ACC-1 level showed a significant increase in rats exposed to HA for 1 and 3 days. In contrast, the hepatic level of AMPK showed a significant reduction throughout the experimental period. Plasma FFA concentrations did not show any significant changes following HA exposure. Thus, increased hepatic FA oxidation and synthesis in the early phase of HA exposure may be among the important mechanisms for the rats to respond to the hypoxic stress in order to acclimatize themselves to the

  17. Elevation of circulating miR-210-3p in high-altitude hypoxic environment

    Directory of Open Access Journals (Sweden)

    Yan eYan

    2016-03-01

    Full Text Available Background: The induction of miR-210-3p, a master hypoxamir, is a consistent feature of the hypoxic response in both normal and malignant cells. However, whether miR-210-3p acts as a circulating factor in response to a hypoxic environment remains unknown. The current study aimed to examine the effect of a high-altitude hypoxic environment on circulating miR-210-3p.Methods: We examined and compared the levels of miR-210-3p using TaqMan-based qRT-PCR in both peripheral blood cells and plasma from 84 ethnic Chinese Tibetans residing at 3560 m, 46 newly arrived migrant Han Chinese (Tibet Han and 82 Han Chinese residing at 8.9 m (Nanjing Han. Furthermore, we analyzed the correlations of miR-210-3p with hematological indices. Results: The relative concentrations of miR-210-3p to internal reference U6 in blood cells were significantly higher in the Tibet Han group (1.01±0.11, P<0.001 and in the Tibetan group (1.17±0.09, P<0.001 than in the Nanjing Han group (0.51±0.04. The absolute concentrations of plasma miR-210-3p were also markedly elevated in the Tibet Han group (503.54±42.95 fmol/L, P=0.004 and in the Tibetan group (557.78±39.84 fmol/L, P<0.001 compared to the Nanjing Han group (358.39±16.16 fmol/L. However, in both blood cells and plasma, miR-210-3p levels were not significantly different between the Tibet Han group and the Tibetan group (P=0.280, P=0.620, respectively. Plasma miR-210-3p concentrations were positively correlated with miR-210-3p levels in blood cells (r=0.192, P=0.005. Furthermore, miR-210-3p levels in both blood cells and plasma showed strong positive correlations with red blood cell counts and hemoglobin and hematocrit values. Conclusion: These data demonstrated, for the first time, that miR-210-3p might act as a circulating factor in response to hypoxic environments and could be associated with human adaptation to life at high altitudes.

  18. Late Holocene spatio-temporal variability of the south Greenland Ice Sheet and adjacent mountain glaciers

    Science.gov (United States)

    Sinclair, G.; Carlson, A. E.; Rood, D. H.; Axford, Y.

    2017-12-01

    The late Holocene, with its spatially complex pattern of centennial-scale climate variation, is an ideal time period to test the response of the cryosphere to atmospheric and oceanic temperature changes. The south Greenland Ice Sheet (sGrIS), with its proximity to areas of North Atlantic Deep Water formation and a large spectrum of glaciological regimes over a relatively small area, provides an excellent location to examine the spatial heterogeneity of ice-sheet and glacier responses to climate change. Here, we will present 50 Be-10 surface exposure ages from eight moraines in six locations around the margin of the sGrIS. These moraines are located just outboard of historical moraines, and will therefore allow us to constrain the timing of the most extensive prehistoric late-Holocene advance and retreat of ice margins draining the sGrIS and independent valley glaciers. The dataset includes both marine- and land-terminating glaciers draining the sGrIS, the low-altitude Qassimiut lobe, the high-altitude alpine Julianhåb ice cap and isolated valley glaciers. This diverse dataset will allow us to determine to what extent late-Holocene centennial-scale behavior of the ice-sheet and glacier margins were synchronous, perhaps in response to an external climate forcing, or more stochastic, governed instead by local factors such as basal thermal regime, bedrock topography, or microclimates. This has implications for understanding the forcings and responses of cryospheric changes at timescales relevant to human society. In addition to providing context for paleoclimatic and glacial geologic investigations, this work will inform future sea-level projections by providing targets for validating high-resolution ice-sheet and glacier models.

  19. A statistical study of high-altitude electric fields measured on the Viking satellite

    International Nuclear Information System (INIS)

    Lindqvist, P.A.; Marklund, G.T.

    1990-01-01

    Characteristics of high-altitude data from the Viking electric field instrument are presented in a statistical study based on 109 Viking orbits. The study is focused in particular on the signatures of and relationships between various parameters measured by the electric field instrument, such as the parallel and transverse (to B) components of the electric field instrument, such as electric field variability. A major goal of the Viking mission was to investigate the occurrence and properties of parallel electric fields and their role in the auroral acceleration process. The results in this paper on the altitude distribution of the electric field variability confirm earlier findings on the distribution of small-scale electric fields and indicate the presence of parallel fields up to about 11,000 km altitude. The directly measured parallel electric field is also investigated in some detail. It is in general directed upward with an average value of 1 mV/m, but depends on, for example, altitude and plasma density. Possible sources of error in the measurement of the parallel field are also considered and accounted for

  20. Perseus A High Altitude Remotely Piloted Aircraft being Towed in Flight

    Science.gov (United States)

    1994-01-01

    Perseus A, a remotely piloted, high-altitude research vehicle designed by Aurora Flight Sciences Corp., takes off from Rogers Dry Lake at the Dryden Flight Research Center, Edwards, California. The Perseus was towed into the air by a ground vehicle. At about 700 ft. the aircraft was released and the engine turned the propeller to take the plane to its desired altitude. Perseus B is a remotely piloted aircraft developed as a design-performance testbed under NASA's Environmental Research Aircraft and Sensor Technology (ERAST) project. Perseus is one of several flight vehicles involved in the ERAST project. A piston engine, propeller-powered aircraft, Perseus was designed and built by Aurora Flight Sciences Corporation, Manassas, Virginia. The objectives of Perseus B's ERAST flight tests have been to reach and maintain horizontal flight above altitudes of 60,000 feet and demonstrate the capability to fly missions lasting from 8 to 24 hours, depending on payload and altitude requirements. The Perseus B aircraft established an unofficial altitude record for a single-engine, propeller-driven, remotely piloted aircraft on June 27, 1998. It reached an altitude of 60,280 feet. In 1999, several modifications were made to the Perseus aircraft including engine, avionics, and flight-control-system improvements. These improvements were evaluated in a series of operational readiness and test missions at the Dryden Flight Research Center, Edwards, California. Perseus is a high-wing monoplane with a conventional tail design. Its narrow, straight, high-aspect-ratio wing is mounted atop the fuselage. The aircraft is pusher-designed with the propeller mounted in the rear. This design allows for interchangeable scientific-instrument payloads to be placed in the forward fuselage. The design also allows for unobstructed airflow to the sensors and other devices mounted in the payload compartment. The Perseus B that underwent test and development in 1999 was the third generation of the

  1. Hydrological processes in glacierized high-altitude basins of the western Himalayas

    Science.gov (United States)

    Jeelani, Ghulam; Shah, Rouf A.; Fryar, Alan E.; Deshpande, Rajendrakumar D.; Mukherjee, Abhijit; Perrin, Jerome

    2018-03-01

    Western Himalaya is a strategically important region, where the water resources are shared by China, India and Pakistan. The economy of the region is largely dependent on the water resources delivered by snow and glacier melt. The presented study used stable isotopes of water to further understand the basin-scale hydro-meteorological, hydrological and recharge processes in three high-altitude mountainous basins of the western Himalayas. The study provided new insights in understanding the dominant factors affecting the isotopic composition of the precipitation, snowpack, glacier melt, streams and springs. It was observed that elevation-dependent post-depositional processes and snowpack evolution resulted in the higher isotopic altitude gradient in snowpacks. The similar temporal trends of isotopic signals in rivers and karst springs reflect the rapid flow transfer due to karstification of the carbonate aquifers. The attenuation of the extreme isotopic input signal in karst springs appears to be due to the mixing of source waters with the underground karst reservoirs. Basin-wise, the input-output response demonstrates the vital role of winter precipitation in maintaining the perennial flow in streams and karst springs in the region. Isotopic data were also used to estimate the mean recharge altitude of the springs.

  2. Natural Environmental Hazards Reflected in High-Altitude Patagonian Lake Sediments (lake Caviahue, Argentina)

    Science.gov (United States)

    Müller, Anne; Scharf, Burkhard; von Tümpling, Wolf; Pirrung, Michael

    2009-03-01

    Two 6-m long sediment cores drilled in the two basins of Lake Caviahue give new evidence of the impact of natural hazards such as ash fallouts linked to nearby volcanic eruptions in the ecologically sensitive environment of the high-altitude region of the Argentinan Patagonian Andes. The two cores show distinct signals of changes in autochthonous productivity and terrigenous input into the lake from ash fallout as well as from river load and shore erosion. Multiproxy records of the sediments indicate whether these changes can be related to volcanic activity. High values of magnetic susceptibility in the cores reflect periods of basaltic ash fallouts during eruptions of the nearby Copahue Volcano. The southern basin is located in the prevalent direction of ash fallouts and has been affected by these volcanic inputs more intensely than the northern basin of the lake. In contrast, sedimentation and authochthonous productivity in the northern basin are strongly affected by fluvial inputs such as suspended river load and acidic stream waters.

  3. Nitrogen mineralization in a high altitude ecosystem in the mediterranean phytogeographical region of Turkey.

    Science.gov (United States)

    Guleryuz, Gurcan; Gucel, Salih; Ozturk, Munir

    2010-07-01

    Interrelations exist in the terrestrial ecosystems between the plant type and characteristics of nutrient uptake. Annual net nitrogen mineralization in soils of different plant communities in the high altitude zone of Spil mountain located in the Mediterranean phytogeographical region of Turkey was investigated throughout one year by field incubation method. Seasonal fluctuations resulting from field incubation were markedly higher in autumn and spring than summer. These are mainly associated with the changes in soil moisture being at minimum in the Mediterranean summer. A significant correlation was developed between the net Nitrate (kg NO3(-)-N ha week(-1)) production and soil water content (p<0.05; r = 0.316 in soil of 0-5 cm; r = 0.312 in soil of 5-15 cm). The results showed that the annual productivity of nitrogen mineralization shows different values depending on communities. Annual net ammonium (NH4(+)-N) production in the soils of each community was negatively estimated. However annual net nitrate (NO3(-)-N) production (0-15 cm) was higher in grassland (27.8 kg ha y(-1)) and shrub (25.0 kg ha y(-1)) than forest (12.4 kg ha y(-1)) community. While annual net N(min) values were close to each other in grassland (14.5 kg ha y(-1)) and shrub (14.1 kg ha y(-1)), but negative in forest community (-3.6 kg ha y(-1)). The reasons for these differences are discussed.

  4. Estimates of Carbon Reservoirs in High-Altitude Wetlands in the Colombian Andes

    Directory of Open Access Journals (Sweden)

    Enrique Javier Peña

    2009-10-01

    Full Text Available The observed increase in emission of greenhouse gases, with attendant effects on global warming, have raised interests in identifying sources and sinks of carbon in the environment. Terrestrial carbon (C sequestration involves capture of atmospheric C through photosynthesis and storage in biota, soil and wetlands. Particularly, wetland systems function primarily as long-term reservoirs for atmospheric carbon dioxide (CO2 and as sources of atmospheric methane (CH4. The objective of this study was to evaluate the patterns of carbon reservoirs in two high-altitude wetlands in the central Andean mountain of Colombia. Carbon cycle in both systems is related mainly with the plant biomass dynamics from the littoral zone. Thus, total organic carbon concentrate an average up to 329 kg of N ha-1 and 125 kg of P ha-1 every year vs only 17 kg N ha-1 and 6 kg P ha-1 in the water column of the limnetic zone in the wetland, evidencing spatial differences in carbon concentrations for these types of ecosystems. Results revealed that these systems participate in the balance and sequestration of carbon in the Colombian Andes.

  5. ON THE ORIGIN OF HIGH-ALTITUDE OPEN CLUSTERS IN THE MILKY WAY

    Energy Technology Data Exchange (ETDEWEB)

    Martinez-Medina, L. A.; Pichardo, B.; Moreno, E.; Peimbert, A. [Instituto de Astronomía, Universidad Nacional Autónoma de México, A.P. 70-264, 04510, México, D.F., México (Mexico); Velazquez, H., E-mail: lamartinez@astro.unam.mx [Instituto de Astronomía, Universidad Nacional Autónoma de México, Apartado Postal 877, 22860 Ensenada, B.C., México (Mexico)

    2016-01-20

    We present a dynamical study of the effect of the bar and spiral arms on the simulated orbits of open clusters in the Galaxy. Specifically, this work is devoted to the puzzling presence of high-altitude open clusters in the Galaxy. For this purpose we employ a very detailed observationally motivated potential model for the Milky Way and a careful set of initial conditions representing the newly born open clusters in the thin disk. We find that the spiral arms are able to raise an important percentage of open clusters (about one-sixth of the total employed in our simulations, depending on the structural parameters of the arms) above the Galactic plane to heights beyond 200 pc, producing a bulge-shaped structure toward the center of the Galaxy. Contrary to what was expected, the spiral arms produce a much greater vertical effect on the clusters than the bar, both in quantity and height; this is due to the sharper concentration of the mass on the spiral arms, when compared to the bar. When a bar and spiral arms are included, spiral arms are still capable of raising an important percentage of the simulated open clusters through chaotic diffusion (as tested from classification analysis of the resultant high-z orbits), but the bar seems to restrain them, diminishing the elevation above the plane by a factor of about two.

  6. The High Altitude MMIC Sounding Radiometer on the GLOBAL HAWK: From Technology Development to Science Discovery

    Science.gov (United States)

    Brown, Shannon; Denning, Richard; Lambrigtsen, Bjorn; Lim, Boon; Tanabe, Jordan; Tanner, Alan

    2013-01-01

    This paper presents results from the High Altitude MMIC Sounding Radiometer (HAMSR) during three recent field campaigns on the Global Hawk Unmanned Ariel Vehicles (UAV), focusing on the enabling technology that led to unprecedented observations of significant weather phenomenon, such as thermodynamic evolution of the tropical cyclone core during rapid intensification and the high resolution three dimensional mapping of several atmospheric river events. HAMSR is a 25 channel cross-track scanning microwave sounder with channels near the 60 and 118 GHz oxygen lines and the 183 GHz water vapor line. HAMSR was originally designed and built at the Jet Propulsion Laboratory as a technology demonstrator in 1998. Subsequent to this, HAMSR participated in three NASA hurricane field campaigns, CAMEX-4, TCSP and NAMMA. Beginning in 2008, HAMSR was extensively upgraded to deploy on the NASA Global Hawk (GH) platform and serve as an asset to the NASA sub-orbital program. HAMSR has participated on the Global Hawk during the 2010 Genesis and Rapid Intensification (GRIP) campaign, the 2011 Winter Storms and Atmospheric Rivers (WISPAR) campaign and is currently participating in the NASA Ventures Hurricane and Severe Storm Sentinel (HS3) campaign (2011-2015).

  7. Effects of High Altitude on Sleep and Respiratory System and Theirs Adaptations

    Directory of Open Access Journals (Sweden)

    Turhan San

    2013-01-01

    Full Text Available High-altitude (HA environments have adverse effects on the normal functioning body of people accustomed to living at low altitudes because of the change in barometric pressure which causes decrease in the amount of oxygen leading to hypobaric hypoxia. Sustained exposure to hypoxia has adverse effects on body weight, muscle structure and exercise capacity, mental functioning, and sleep quality. The most important step of acclimatization is the hyperventilation which is achieved by hypoxic ventilatory response of the peripheral chemoreceptors. Hyperventilation results in increase in arterial carbondioxide concentration. Altitude also affects sleep and cardiac output, which is the other determinant of oxygen delivery. Upon initial exposure to HA, the resting pulse rate increases rapidly, but with acclimatization, heart rate and cardiac output tend to fall. Another important component that leads to decrease in cardiac output is the reduction in the stroke volume with acclimatization. During sleep at HA, the levels of CO2 in the blood can drop very low and this can switch off the drive to breathe. Only after the body senses a further drop in O2 levels breathing is started again. Periodic breathing is thought to result from instability in the control system through the hypoxic drive or the response to CO2.

  8. Effects of high altitude training on exercise capacity: fact or myth.

    Science.gov (United States)

    de Paula, Paula; Niebauer, Josef

    2012-03-01

    High altitude training has become a mainstay in endurance sports, with live high-train low as the current protocol of choice. Athletes either live or sleep in artificial or natural hypoxic conditions with the aim to increase serum erythropoietin concentrations, which are thought to improve maximum oxygen uptake and thus exercise performance. Changes, however, are not very striking and only apparent in so-called responders, who are not a well-defined group and may be as little as 50% of the trained study population. Whereas some studies show minor improvement, others report no change or even worsening. Furthermore, the mechanisms behind the proposed beneficial changes remain obscure and are far from being proven. There is an evident lack of sufficiently powered randomized, double-blinded studies, with training protocols that are identical for all groups and groups that are indeed comparable. Several studies discriminate between responders and non-responders, without clearly assessing the characteristics of the so-called responders. Until this has been done, it remains unclear if such a group really exists and how these subjects are characterized. This, however, would be of immense value, so protocols could be tailored to athletes' needs. Taken together, the current literature on natural or artificial hypoxia somewhat documents improved performance at high but not low altitude.

  9. Electrolyte-carbohydrate beverage prevents water loss in the early stage of high altitude training.

    Science.gov (United States)

    Yanagisawa, Kae; Ito, Osamu; Nagai, Satsuki; Onishi, Shohei

    2012-01-01

    To prevent water loss in the early stage of high altitude training, we focused on the effect of electrolyte-carbohydrate beverage (EC). Subjects were 16 male university students who belonged to a ski club. They had ski training at an altitude of 1,800 m. The water (WT) group drank only water, and the EC group drank only an electrolyte-carbohydrate beverage. They arrived at the training site in the late afternoon. The study started at 7 pm on the day of arrival and continued until noon of the 4(th) day. In the first 12 hours, 1 L of beverages were given. On the second and third days, 2.5 L of beverages were given. All subjects ate the same meals. Each morning while in fasting condition, subjects were weighed and blood was withdrawn for various parameters (hemoglobin, hematocrit, sodium, potassium and aldosterone). Urine was collected at 12 hour intervals for a total 60 hours (5 times). The urine volume, gravity, sodium and potassium concentrations were measured. Peripheral oxygen saturation and heart rate were measured during sleep with a pulse oximeter. Liquid intakes in both groups were similar, hence the electrolytes intake was higher in the EC group than in the WT group. The total urine volume was lower in the EC group than in the WT group, respectively (paltitude training may be effective in decreasing urinary output and preventing loss of blood plasma volume.

  10. Wave particle interactions in the high-altitude polar cusp: a Cluster case study

    Directory of Open Access Journals (Sweden)

    B. Grison

    2005-12-01

    Full Text Available On 23 March 2002, the four Cluster spacecraft crossed in close configuration (~100 km separation the high-altitude (10 RE cusp region. During a large part of the crossing, the STAFF and EFW instruments have detected strong electromagnetic wave activity at low frequencies, especially when intense field-aligned proton fluxes were detected by the CIS/HIA instrument. In all likelihood, such fluxes correspond to newly-reconnected field lines. A focus on one of these ion injection periods highlights the interaction between waves and protons. The wave activity has been investigated using the k-filtering technique. Experimental dispersion relations have been built in the plasma frame for the two most energetic wave modes. Results show that kinetic Alfvén waves dominate the electromagnetic wave spectrum up to 1 Hz (in the spacecraft frame. Above 0.8 Hz, intense Bernstein waves are also observed. The close simultaneity observed between the wave and particle events is discussed as an evidence for local wave generation. A mechanism based on current instabilities is consistent with the observations of the kinetic Alfvén waves. A weak ion heating along the recently-opened field lines is also suggested from the examination of the ion distribution functions. During an injection event, a large plasma convection motion, indicative of a reconnection site location, is shown to be consistent with the velocity perturbation induced by the large-scale Alfvén wave simultaneously detected.

  11. Wave particle interactions in the high-altitude polar cusp: a Cluster case study

    Directory of Open Access Journals (Sweden)

    B. Grison

    2005-12-01

    Full Text Available On 23 March 2002, the four Cluster spacecraft crossed in close configuration (~100 km separation the high-altitude (10 RE cusp region. During a large part of the crossing, the STAFF and EFW instruments have detected strong electromagnetic wave activity at low frequencies, especially when intense field-aligned proton fluxes were detected by the CIS/HIA instrument. In all likelihood, such fluxes correspond to newly-reconnected field lines. A focus on one of these ion injection periods highlights the interaction between waves and protons. The wave activity has been investigated using the k-filtering technique. Experimental dispersion relations have been built in the plasma frame for the two most energetic wave modes. Results show that kinetic Alfvén waves dominate the electromagnetic wave spectrum up to 1 Hz (in the spacecraft frame. Above 0.8 Hz, intense Bernstein waves are also observed. The close simultaneity observed between the wave and particle events is discussed as an evidence for local wave generation. A mechanism based on current instabilities is consistent with the observations of the kinetic Alfvén waves. A weak ion heating along the recently-opened field lines is also suggested from the examination of the ion distribution functions. During an injection event, a large plasma convection motion, indicative of a reconnection site location, is shown to be consistent with the velocity perturbation induced by the large-scale Alfvén wave simultaneously detected.

  12. Origin of the turbulent spectra in the high-altitude cusp: Cluster spacecraft observations

    Directory of Open Access Journals (Sweden)

    K. Nykyri

    2006-05-01

    Full Text Available High-resolution magnetic field data from Cluster Flux Gate Magnetometer (FGM and the Spatio-Temporal Analysis of Field Fluctuations (STAFF instruments are used to study turbulent magnetic field fluctuations during the high-altitude cusp crossing on 17 March 2001. Despite the quiet solar wind conditions, the cusp was filled with magnetic field turbulence whose power correlates with the field-aligned ion plasma flux. The magnetic field wave spectra shows power law behavior with both double and single slopes with break in the spectra usually occurring in the vicinity of the local ion cyclotron frequency. Strong peaks in the wave power close to local ion cyclotron frequency were sometimes observed, with secondary peaks at higher harmonics indicative of resonant processes between protons and the waves. We show that the observed spectral break point may be caused partly by damping of obliquely propagating kinetic Alfvén (KAW waves and partly by cyclotron damping of ion cyclotron waves.

  13. Structural modifications of the brain in acclimatization to high-altitude.

    Directory of Open Access Journals (Sweden)

    Jiaxing Zhang

    Full Text Available Adaptive changes in respiratory and cardiovascular responses at high altitude (HA have been well clarified. However, the central mechanisms underlying HA acclimatization remain unclear. Using voxel-based morphometry (VBM and diffusion tensor imaging (DTI with fractional anisotropy (FA calculation, we investigated 28 Han immigrant residents (17-22 yr born and raised at HA of 2616-4200 m in Qinghai-Tibetan Plateau for at least 17 years and who currently attended college at sea-level (SL. Their family migrated from SL to HA 2-3 generations ago and has resided at HA ever since. Control subjects were matched SL residents. HA residents (vs. SL showed decreased grey matter volume in the bilateral anterior insula, right anterior cingulate cortex, bilateral prefrontal cortex, left precentral cortex, and right lingual cortex. HA residents (vs. SL had significantly higher FA mainly in the bilateral anterior limb of internal capsule, bilateral superior and inferior longitudinal fasciculus, corpus callosum, bilateral superior corona radiata, bilateral anterior external capsule, right posterior cingulum, and right corticospinal tract. Higher FA values in those regions were associated with decreased or unchanged radial diffusivity coinciding with no change of longitudinal diffusivity in HA vs. SL group. Conversely, HA residents had lower FA in the left optic radiation and left superior longitudinal fasciculus. Our data demonstrates that HA acclimatization is associated with brain structural modifications, including the loss of regional cortical grey matter accompanied by changes in the white matter, which may underlie the physiological adaptation of residents at HA.

  14. Multi-sensor Array for High Altitude Balloon Missions to the Stratosphere

    Science.gov (United States)

    Davis, Tim; McClurg, Bryce; Sohl, John

    2008-10-01

    We have designed and built a microprocessor controlled and expandable multi-sensor array for data collection on near space missions. Weber State University has started a high altitude research balloon program called HARBOR. This array has been designed to data log a base set of measurements for every flight and has room for six guest instruments. The base measurements are absolute pressure, on-board temperature, 3-axis accelerometer for attitude measurement, and 2-axis compensated magnetic compass. The system also contains a real time clock and circuitry for logging data directly to a USB memory stick. In typical operation the measurements will be cycled through in sequence and saved to the memory stick along with the clock's time stamp. The microprocessor can be reprogrammed to adapt to guest experiments with either analog or digital interfacing. This system will fly with every mission and will provide backup data collection for other instrumentation for which the primary task is measuring atmospheric pressure and temperature. The attitude data will be used to determine the orientation of the onboard camera systems to aid in identifying features in the images. This will make these images easier to use for any future GIS (geographic information system) remote sensing missions.

  15. Plasma proteomic study in patients with high altitude pulmonary edema (HAPE

    Directory of Open Access Journals (Sweden)

    Yong-jun LUO

    2012-01-01

    Full Text Available Objective  To investigate the differential expressions of protein in the plasma proteome in patients suffering from high altitude pulmonary edema (HAPE and their implications. Methods  The plasmas of six HAPE patients and six healthy controls were studied. The high-abundant proteins in the plasma were removed. The low-abundant proteins in the plasma/serum were segregated by 2-DE. MALDI-TOF/MS was adopted to measure the peptide fingerprints after the differential protein spots were digested by enzymes. Comparison and analysis were made in the GenBank. Results  The immunoglobulin K1 light chain, serum transferrin protein precursor, and α-trypsin inhibitor heavy chain-related protein expressions were upregulated in HAPE patients compared with the control group. However the human fibrin glue coagulation protein 3 was down-regulated. Conclusion  The differential expression of the above four proteins in the plasma of HAPE patients may be related to the occurrence of HAPE and can be used as the target point for the prediction of HAPE.

  16. Dirrofilariasis in Shepherd Dogs of High Altitudes Areas in West Azerbaijan-Iran

    Directory of Open Access Journals (Sweden)

    Mojtaba Hadian

    2011-03-01

    Full Text Available Although the biology and ecology of the arthropod vectors are different, some factors, such as global warming, the increasing abundance of mosquitoes, the movement of domestic hosts, and the abundance of wild reservoirs, can act as favourable factors for the distribution of infections. The aim of this study was to determine the prevalence of Dirofilaria immitis infection in shepherd dogs living in the high altitude of mountainous area (i.e.1200 meters above the sea level. The study group was comprised of 160 shepherd dogs living in 4 mountainous regions (Targavar, Margavar, Kolshin and Hovarchin of west Azerbaijan where continuous movement of sheep and goat flocks resulted to have a little information about shepherd dogs in these regions. Additionally, arduous pathways have made impossible any access by car to some territories of these areas. The dogs were mostly mixed raced with different ages (from 1 to 10 years and sexes (male = 136, female = 24. Blood samples were collected from cephalic vein. Direct thin and thick blood smears and modified knott’s technique were used for detecting D.immitis microfilariae and other blood parasites. The results indicated that 40 (25 % of dogs were infected with D. immitis microfilariae. In examination of the dogs, no severe life threatening feature of the disease was diagnosed. There were no significant differences (P > 0.05 of Dirrofilaria infection among gender, age groups and geographical areas. High prevalence of asymptomatic Dirrofilariasis in shepherd dogs in this area highlights the need of controlling and preventive programs.

  17. High Altitude Balloon Flight Path Prediction and Site Selection Based On Computer Simulations

    Science.gov (United States)

    Linford, Joel

    2010-10-01

    Interested in the upper atmosphere, Weber State University Physics department has developed a High Altitude Reconnaissance Balloon for Outreach and Research team, also known as HARBOR. HARBOR enables Weber State University to take a variety of measurements from ground level to altitudes as high as 100,000 feet. The flight paths of these balloons can extend as long as 100 miles from the launch zone, making the choice of where and when to fly critical. To ensure the ability to recover the packages in a reasonable amount of time, days and times are carefully selected using computer simulations limiting flight tracks to approximately 40 miles from the launch zone. The computer simulations take atmospheric data collected by National Oceanic and Atmospheric Administration (NOAA) to plot what flights might have looked like in the past, and to predict future flights. Using these simulations a launch zone has been selected in Duchesne Utah, which has hosted eight successful flights over the course of the last three years, all of which have been recovered. Several secondary launch zones in western Wyoming, Southern Idaho, and Northern Utah are also being considered.

  18. A telescopic cinema sound camera for observing high altitude aerospace vehicles

    Science.gov (United States)

    Slater, Dan

    2014-09-01

    Rockets and other high altitude aerospace vehicles produce interesting visual and aural phenomena that can be remotely observed from long distances. This paper describes a compact, passive and covert remote sensing system that can produce high resolution sound movies at >100 km viewing distances. The telescopic high resolution camera is capable of resolving and quantifying space launch vehicle dynamics including plume formation, staging events and payload fairing jettison. Flight vehicles produce sounds and vibrations that modulate the local electromagnetic environment. These audio frequency modulations can be remotely sensed by passive optical and radio wave detectors. Acousto-optic sensing methods were primarily used but an experimental radioacoustic sensor using passive micro-Doppler radar techniques was also tested. The synchronized combination of high resolution flight vehicle imagery with the associated vehicle sounds produces a cinema like experience that that is useful in both an aerospace engineering and a Hollywood film production context. Examples of visual, aural and radar observations of the first SpaceX Falcon 9 v1.1 rocket launch are shown and discussed.

  19. Hydrogen Fuel System Design Trades for High-Altitude Long-Endurance Remotely- Operated Aircraft

    Science.gov (United States)

    Millis, Marc G.; Tornabene, Robert T.; Jurns, John M.; Guynn, Mark D.; Tomsik, Thomas M.; VanOverbeke, Thomas J.

    2009-01-01

    Preliminary design trades are presented for liquid hydrogen fuel systems for remotely-operated, high-altitude aircraft that accommodate three different propulsion options: internal combustion engines, and electric motors powered by either polymer electrolyte membrane fuel cells or solid oxide fuel cells. Mission goal is sustained cruise at 60,000 ft altitude, with duration-aloft a key parameter. The subject aircraft specifies an engine power of 143 to 148 hp, gross liftoff weight of 9270 to 9450 lb, payload of 440 lb, and a hydrogen fuel capacity of 2650 to 2755 lb stored in two spherical tanks (8.5 ft inside diameter), each with a dry mass goal of 316 lb. Hydrogen schematics for all three propulsion options are provided. Each employs vacuum-jacketed tanks with multilayer insulation, augmented with a helium pressurant system, and using electric motor driven hydrogen pumps. The most significant schematic differences involve the heat exchangers and hydrogen reclamation equipment. Heat balances indicate that mission durations of 10 to 16 days appear achievable. The dry mass for the hydrogen system is estimated to be 1900 lb, including 645 lb for each tank. This tank mass is roughly twice that of the advanced tanks assumed in the initial conceptual vehicle. Control strategies are not addressed, nor are procedures for filling and draining the tanks.

  20. Salinity drives archaeal distribution patterns in high altitude lake sediments on the Tibetan Plateau.

    Science.gov (United States)

    Liu, Yongqin; Priscu, John C; Xiong, Jinbo; Conrad, Ralf; Vick-Majors, Trista; Chu, Haiyan; Hou, Juzhi

    2016-03-01

    Archaeal communities and the factors regulating their diversity in high altitude lakes are poorly understood. Here, we provide the first high-throughput sequencing study of Archaea from Tibetan Plateau lake sediments. We analyzed twenty lake sediments from the world's highest and largest plateau and found diverse archaeal assemblages that clustered into groups dominated by methanogenic Euryarchaeota, Crenarchaeota and Halobacteria/mixed euryarchaeal phylotypes. Statistical analysis inferred that salinity was the major driver of community composition, and that archaeal diversity increased with salinity. Sediments with the highest salinities were mostly dominated by Halobacteria. Crenarchaeota dominated at intermediate salinities, and methanogens were present in all lake sediments, albeit most abundant at low salinities. The distribution patterns of the three functional types of methanogens (hydrogenotrophic, acetotrophic and methylotrophic) were also related to changes in salinity. Our results show that salinity is a key factor controlling archaeal community diversity and composition in lake sediments on a spatial scale that spans nearly 2000 km on the Tibetan Plateau. © FEMS 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  1. Characterization and speciation of mercury in mosses and lichens from the high-altitude Tibetan Plateau.

    Science.gov (United States)

    Shao, Jun-Juan; Liu, Cheng-Bin; Zhang, Qing-Hua; Fu, Jian-Jie; Yang, Rui-Qiang; Shi, Jian-Bo; Cai, Yong; Jiang, Gui-Bin

    2017-06-01

    The accumulation and species of mercury (Hg) in mosses and lichens collected from high-altitude Tibetan Plateau were studied. The altitudes of the sampling sites spanned from 1983 to 5147 m, and a total of 130 mosses and 52 lichens were analyzed. The total mercury (THg) contents in mosses and lichens were in the ranges of 13.1-273.0 and 20.2-345.9 ng/g, respectively. The average ratios of methylmercury (MeHg) in THg in mosses and lichens were 2.4 % (0.3-11.1 %) and 2.7 % (0.4-9.6 %), respectively, which were higher than those values reported in other regions. The contents of THg in both mosses and lichens were not correlated with the THg in soils (p > 0.05). The lipid contents displayed a significantly positive correlation with concentrations of MeHg in mosses (r = 0.461, p Tibetan Plateau.

  2. Design of High Altitude Long Endurance UAV: Structural Analysis of Composite Wing using Finite Element Method

    Science.gov (United States)

    Kholish Rumayshah, Khodijah; Prayoga, Aditya; Mochammad Agoes Moelyadi, Ing., Dr.

    2018-04-01

    Research on a High Altitude Long Endurance (HALE) Unmanned Aerial Vehicle (UAV) is currently being conducted at Bandung Institute of Technology (ITB). Previously, the 1st generation of HALE UAV ITB used balsa wood for most of its structure. Flight test gave the result of broken wings due to extreme side-wind that causes large bending to its high aspect ratio wing. This paper conducted a study on designing the 2nd generation of HALE UAV ITB which used composite materials in order to substitute balsa wood at some critical parts of the wing’s structure. Finite element software ABAQUS/CAE is used to predict the stress and deformation that occurred. Tsai-Wu and Von-Mises failure criteria were applied to check whether the structure failed or not. The initial configuration gave the results that the structure experienced material failure. A second iteration was done by proposing a new configuration and it was proven safe against the load given.

  3. Chemoreceptor Responsiveness at Sea Level Does Not Predict the Pulmonary Pressure Response to High Altitude.

    Science.gov (United States)

    Hoiland, Ryan L; Foster, Glen E; Donnelly, Joseph; Stembridge, Mike; Willie, Chris K; Smith, Kurt J; Lewis, Nia C; Lucas, Samuel J E; Cotter, Jim D; Yeoman, David J; Thomas, Kate N; Day, Trevor A; Tymko, Mike M; Burgess, Keith R; Ainslie, Philip N

    2015-07-01

    The hypoxic ventilatory response (HVR) at sea level (SL) is moderately predictive of the change in pulmonary artery systolic pressure (PASP) to acute normobaric hypoxia. However, because of progressive changes in the chemoreflex control of breathing and acid-base balance at high altitude (HA), HVR at SL may not predict PASP at HA. We hypothesized that resting oxygen saturation as measured by pulse oximetry (Spo₂) at HA would correlate better than HVR at SL with PASP at HA. In 20 participants at SL, we measured normobaric, isocapnic HVR (L/min · -%Spo₂⁻¹) and resting PASP using echocardiography. Both resting Spo₂ and PASP measures were repeated on day 2 (n = 10), days 4 to 8 (n = 12), and 2 to 3 weeks (n = 8) after arrival at 5,050 m. These data were also collected at 5,050 m in life-long HA residents (ie, Sherpa [n = 21]). Compared with SL, Spo₂ decreased from 98.6% to 80.5% (P HVR at SL was not related to Spo₂ or PASP at any time point at 5,050 m (all P > .05). Sherpa had lower PASP (P .50), there was a weak relationship in the Sherpa (R² = 0.16, P = .07). We conclude that neither HVR at SL nor resting Spo₂ at HA correlates with elevations in PASP at HA.

  4. Response of the Atmospheric Boundary Layer and Soil Layer to a High Altitude, Dense Aerosol Cover.

    Science.gov (United States)

    Garratt, J. R.; Pittock, A. B.; Walsh, K.

    1990-01-01

    The response of the atmospheric boundary layer to the appearance of a high-altitude smoke layer has been investigated in a mesoscale numerical model of the atmosphere. Emphasis is placed on the changes in mean boundary-layer structure and near-surface temperatures when smoke of absorption optical depth (AOD) in the, range 0 to 1 is introduced. Calculations have been made at 30°S, for different soil thermal properties and degrees of surface wetness, over a time period of several days during which major smoke-induced cooling occurs. The presence of smoke reduces the daytime mixed-layer depth and, for large enough values of AOD, results in a daytime surface inversion with large cooling confined to heights of less than a few hundred meters. Smoke-induced reductions in daytime soil and air temperatures of several degrees are typical, dependent critically upon soil wetness and smoke AOD. Locations near the coast experience reduced cooling whenever there is a significant onshore flow related to a sea breeze (this would also be the case with a large-scale onshore flow). The sea breeze itself disappears for large enough smoke AOD and, over sloping coastal terrain, a smoke-induced, offshore drainage flow may exist throughout the diurnal cycle.

  5. Butterflies of the high altitude Atacama Desert: habitat use and conservation

    Directory of Open Access Journals (Sweden)

    Emma eDespland

    2014-09-01

    Full Text Available The butterfly fauna of the high-altitude desert of Northern Chile, though depauperate, shows high endemism, is poorly known and is of considerable conservation concern. This study surveys butterflies along the Andean slope between 2400 and 500 m asl (prepuna, puna and Andean steppe habitats as well as in high and low altitude wetlands and in the neoriparian vegetation of agricultural sites. We also include historical sightings from museum records. We compare abundances between altitudes, between natural and impacted sites, as well as between two sampling years with different precipitation regimes. The results confirm high altitudinal turnover and show greatest similarity between wetland and slope faunas at similar altitudes. Results also underscore vulnerability to weather fluctuations, particularly in the more arid low-altitude sites, where abundances were much lower in the low precipitation sampling season and several species were not observed at all. Finally, we show that some species have shifted to the neoriparian vegetation of the agricultural landscape, whereas others were only observed in less impacted habitats dominated by native plants. These results suggest that acclimation to novel habitats depends on larval host plant use. The traditional agricultural environment can provide habitat for many, but not all, native butterfly species, but an estimation of the value of these habitats requires better understanding of butterfly life-history strategies and relationships with host plants.

  6. Safe-Site Effects on Rhizosphere Bacterial Communities in a High-Altitude Alpine Environment

    Directory of Open Access Journals (Sweden)

    Sonia Ciccazzo

    2014-01-01

    Full Text Available The rhizosphere effect on bacterial communities associated with three floristic communities (RW, FI, and M sites which differed for the developmental stages was studied in a high-altitude alpine ecosystem. RW site was an early developmental stage, FI was an intermediate stage, M was a later more matured stage. The N and C contents in the soils confirmed a different developmental stage with a kind of gradient from the unvegetated bare soil (BS site through RW, FI up to M site. The floristic communities were composed of 21 pioneer plants belonging to 14 species. Automated ribosomal intergenic spacer analysis showed different bacterial genetic structures per each floristic consortium which differed also from the BS site. When plants of the same species occurred within the same site, almost all their bacterial communities clustered together exhibiting a plant species effect. Unifrac significance value (P<0.05 on 16S rRNA gene diversity revealed significant differences (P<0.05 between BS site and the vegetated sites with a weak similarity to the RW site. The intermediate plant colonization stage FI did not differ significantly from the RW and the M vegetated sites. These results pointed out the effect of different floristic communities rhizospheres on their soil bacterial communities.

  7. Limnology and cyanobacterial diversity of high altitude lakes of Lahaul-Spiti in Himachal Pradesh, India.

    Science.gov (United States)

    Singh, Y; Khattar, Jis; Singh, D P; Rahi, P; Gulati, A

    2014-09-01

    Limnological data of four high altitude lakes from the cold desert region of Himachal Pradesh, India, has been correlated with cyanobacterial diversity. Physico-chemical characteristics and nutrient contents of the studied lakes revealed that Sissu Lake is mesotrophic while Chandra Tal, Suraj Tal and Deepak Tal are ultra-oligotrophic. Based on morphology and 16S rRNA gene sequence, a total of 20 cyanobacterial species belonging to 11 genera were identified. Canonical correspondence analysis distinguished three groups of species with respect to their occurrence and nutrient/physical environment demand. The first group, which included Nostoc linckia, N. punctiforme, Nodularia sphaerocarpa, Geitlerinema acutissimum, Limnothrix redekii, Planktothrix agardhii and Plank. clathrata, was characteristic of water with high nutrient content and high temperature. The second group, including Gloeocapsopsis pleurocapsoides, Leptolyngbya antarctica, L. frigida, Pseudanabaena frigida and N. spongiaeforme, occurred in oligotrophic water with high pH and low temperature. The distribution of third group of Cyanobium parvum, Synechocystis pevalekii, L. benthonica, L. foveolarum, L. lurida, L. valderiana, Phormidium autumnale and P. chalybeum could not be associated with a particular environmental condition because of their presence in all sampling sites.

  8. Research of biofuels on performance, emission and noise of diesel engine under high-altitude area

    Science.gov (United States)

    Xu, Kai; Huang, Hua

    2018-05-01

    At high altitudes and with no any adjustment for diesel engine, comparative experiments on a diesel engine about the engine's performance, emission and exhaust noise, are carried out by combusting different biofuels (pure diesel (D100), biodiesel (B100), and ethanol-biodiesel (E20)). The test results show that: compared with D100, the power performance of combusting B100 and E20 decreases, and the average drop of the torque at full-load are 4.5% and 5.7%. The equivalent fuel consumption is lower than that of diesel fuel, The decline of oil consumption rate 3˜10g/ (kW • h); At low load the emission of NOx decreases, Hat high loads, equal and higher than D100; the soot emissions decreases heavier, among them, E20 carbon dioxide emissions improved considerably; An full-load exhaust noise of B100 decreases average 3.6dB(A), E20 decreases average 4.8dB(A); In road simulation experiments exhaust noise max decreases 8.5dB(A).

  9. Silver and lead in high-altitude lake sediments: Proxies for climate changes and human activities

    International Nuclear Information System (INIS)

    Garçon, Marion; Chauvel, Catherine; Chapron, Emmanuel; Faïn, Xavier; Lin, Mingfang; Campillo, Sylvain; Bureau, Sarah; Desmet, Marc; Bailly-Maître, Marie-Christine; Charlet, Laurent

    2012-01-01

    High-altitude lake sediments are often used as archives for environmental changes and their chemical and isotopic compositions provide significant constraints on natural and anthropogenic long-term changes that have occurred in their catchment area. Here, trace-element concentrations and Pb isotopes are presented for two sedimentary cores from Lake Blanc Huez in the French Alps, to trace the impact of climate changes and human activities over the Holocene. Lead and Ag contents are very high and clearly dominated by input from a Pb–Ag vein located a few meters from the lakeshore, a vein that also buffers the Pb isotopes. Mining of this vein in medieval times is recorded in the corresponding lake sediments with high Ag content coupled with high Pb/U ratio. These chemical characteristics can be used to constrain the major Holocene climate changes. Significant advances of glaciers next to the lake produced sediments with Ag and Pb concentration peaks and high Pb/U ratios due to accelerated erosion of the Pb–Ag vein, similar to the effects of the medieval mining. In contrast, reduced glacier activity led to the formation of organic-rich sediments with high U and As contents and low Pb/U ratios. More generally, the observed combination of chemical changes could be used elsewhere to decipher environmental changes over long periods of time.

  10. Investigation of junior school student myopia in high-altitude Tibetan areas in Qinghai Province

    Directory of Open Access Journals (Sweden)

    Xia Han

    2014-05-01

    Full Text Available AIM: To know the rate of students' myopia in junior school and factors affecting its occurrence in high altitude Tibetan areas in Qinghai, and provide basis for the prevention of myopia. METHODS: Totally 2 209 junior school students were extracted as respondent with stratified cluster sampling method. The gender, age, ethnicity, grade, eye behavior, physical activity and parental visual conditions were collected by self-made questionnaire, and the curvature of the cornea, anterior chamber depth and axial length were detected. RESULTS: The prevalence of myopia was 48.02%, including the mild myopia, moderate myopia and high myopia were 40.74%, 35.31% and 23.96% respectively. Curvature of the cornea, anterior chamber depth and axial length had statistical difference between normal vision and different degrees of myopia(PPCONCLUSION: Incorrect sitting posture, parental myopia, visual near distance <20cm, incorrect eye exercises and less time for outdoor activities are the main reasons that cause myopia of junior students. The effective prevention and controlled measures should be taken for these factors.

  11. Pruning management of Chardonnay grapevines at high altitude in Brazilian southeast

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    Tania dos Reis Mendonça

    2016-03-01

    Full Text Available ABSTRACT The agronomical responses of Chardonnay, a variety indicated for sparkling wine production, is influenced by the vineyard management and the edaphoclimatic conditions of the region. The objective of this study was to evaluate the effects of two pruning types (Royat and double Guyot on vegetative and reproductive development of Chardonnay vine growing at high altitude in the Brazilian southeastern region. The experiment was carried out in a commercial vineyard located at 1,280 m of altitude in Divinolândia, São Paulo State, Brazil. The Chardonnay vines (clone 96, grafted onto 1103 Paulsen rootstock and trained in a vertical shoot positioning trellis system, were assessed. Vegetative vigor, bud fruitfulness, production and physicochemical composition of grapes were evaluated during 2014 and 2015 growing seasons. The Royat pruning induced higher vegetative vigor and increased the bud fruitfulness, the cluster number and the productivity of Chardonnay vine when compared to Guyot pruning. Even though the increase on yield was observed, there was no effect of pruning type on grape final quality. Therefore, the choice of pruning method in function of variety genetic characteristics and their interaction with environment can optimize the vineyard profitability. In the Brazilian southeast, the Royat system is the most suitable one to grow Chardonnay for sparkling wines production.

  12. Shared and unique signals of high-altitude adaptation in geographically distinct Tibetan populations.

    Directory of Open Access Journals (Sweden)

    Tana Wuren

    Full Text Available Recent studies have used a variety of analytical methods to identify genes targeted by selection in high-altitude populations located throughout the Tibetan Plateau. Despite differences in analytic strategies and sample location, hypoxia-related genes, including EPAS1 and EGLN1, were identified in multiple studies. By applying the same analytic methods to genome-wide SNP information used in our previous study of a Tibetan population (n = 31 from the township of Maduo, located in the northeastern corner of the Qinghai-Tibetan Plateau (4200 m, we have identified common targets of natural selection in a second geographically and linguistically distinct Tibetan population (n = 46 in the Tuo Tuo River township (4500 m. Our analyses provide evidence for natural selection based on iHS and XP-EHH signals in both populations at the p<0.02 significance level for EPAS1, EGLN1, HMOX2, and CYP17A1 and for PKLR, HFE, and HBB and HBG2, which have also been reported in other studies. We highlight differences (i.e., stratification and admixture in the two distinct Tibetan groups examined here and report selection candidate genes common to both groups. These findings should be considered in the prioritization of selection candidate genes in future genetic studies in Tibet.

  13. Psychrophilic anaerobic digestion of guinea pig manure in low-cost tubular digesters at high altitude.

    Science.gov (United States)

    Garfí, Marianna; Ferrer-Martí, Laia; Villegas, Vidal; Ferrer, Ivet

    2011-05-01

    Guinea pig is one of the most common livestock in rural communities of the Andes. The aim of this research was to study the anaerobic digestion of guinea pig manure in low-cost unheated tubular digesters at high altitude. To this end, the performance of two pilot digesters was monitored during 7 months; and two greenhouse designs were compared. In the dome roof digester the temperature and biogas production were significantly higher than in the shed roof digester. However, the biogas production rate was low (0.04 m(biogas)(3)m(digester)(-3) d(-1)), which is attributed to the low organic loading rate (0.6 kg(VS)m(digester)(-3)d(-1)) and temperature (23°C) of the system, among other factors. In a preliminary fertilization study, the potato yield per hectare was increased by 100% using the effluent as biofertilizer. Improving manure management techniques, increasing the organic loading rate and co digesting other substrates may be considered to enhance the process. Copyright © 2011 Elsevier Ltd. All rights reserved.

  14. Cosmic Ray Astrophysics using The High Altitude Water Cherenkov (HAWC Observatory in México

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    de la Fuente Eduardo

    2017-01-01

    Full Text Available The High-Altitude Water Cherenkov (HAWC TeV gamma–ray Observatory in México is ready to search and study gamma-ray emission regions, extremely high-energy cosmic-ray sources, and to identify transient phenomena. With a better Gamma/Hadron rejection method than other similar experiments, it will play a key role in triggering multi–wavelength and multi–messenger studies of active galaxies (AGN, gamma-ray bursts (GRB, supernova remnants (SNR, pulsar wind nebulae (PWN, Galactic Plane Sources, and Cosmic Ray Anisotropies. It has an instantaneous field-of-view of ∼2 str, equivalent to 15% of the whole sky and continuous operation (24 hours per day. The results obtained by HAWC–111 (111 detectors in operation were presented on the proceedings of the International Cosmic Ray Conference 2015 and in [1]. The results obtained by HAWC–300 (full operation are now under analysis and will be published in forthcoming papers starting in 2017 (see preliminary results on http://www.hawc-observatory.org/news/. Here we present the HAWC contributions on cosmic ray astrophysics via anisotropies studies, summarizing the HAWC detector and its upgrading by the installation of “outriggers”.

  15. Evaluating the Capability of High-Altitude Infrasound Platforms to Cover Gaps in Existing Networks.

    Energy Technology Data Exchange (ETDEWEB)

    Bowman, Daniel [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-09-01

    A variety of Earth surface and atmospheric sources generate low frequency sound waves that can travel great distances. Despite a rich history of ground-based sensor studies, very few experiments have investigated the prospects of free floating microphone arrays at high altitudes. However, recent initiatives have shown that such networks have very low background noise and may sample an acoustic wave field that is fundamentally different than that at the Earth's surface. The experiments have been limited to at most two stations at altitude, limiting their utility in acoustic event detection and localization. We describe the deployment of five drifting microphone stations at altitudes between 21 and 24 km above sea level. The stations detected one of two regional ground-based explosions as well as the ocean microbarom while traveling almost 500 km across the American Southwest. The explosion signal consisted of multiple arrivals; signal amplitudes did not correlate with sensor elevation or source range. A sparse network method that employed curved wave front corrections was able to determine the backazimuth from the free flying network to the acoustic source. Episodic broad band signals similar to those seen on previous flights in the same region were noted as well, but their source remains unclear. Background noise levels were commensurate with those on infrasound stations in the International Monitoring System (IMS) below 2 seconds, but sensor self noise appears to dominate at higher frequencies.

  16. Integrating the EMPD with an Alpine altitudinal training set to reconstruct climate variables in Holocene pollen records from high-altitude peat bogs

    Science.gov (United States)

    Furlanetto, Giulia; Badino, Federica; Brunetti, Michele; Champvillair, Elena; De Amicis, Mattia; Maggi, Valter; Pini, Roberta; Ravazzi, Cesare; Vallé, Francesca

    2016-04-01

    Temperatures and precipitation are the main environmental factors influencing vegetation and pollen production. Knowing the modern climate optima and tolerances of those plants represented in fossil assemblages and assuming that the relationships between plants and climate in the past are not dissimilar from the modern ones, fossil pollen records offer many descriptors to reconstruct past climate variables. The aim of our work is to investigate the potential of high-altitude pollen records from an Alpine peat bog (TBValter, close to the Ruitor Glacier, Western Italian Alps) for quantitative paleoclimate estimates. The idea behind is that high-altitude ecosystems are more sensitive to climate changes, especially to changes in July temperatures that severely affect the timberline ecotone. Meantime, we met with difficulties when considering the factors involved in pollen dispersal over a complex altitudinal mountain pattern, such as the Alps. We used the EMPD-European Modern Pollen Database (Davis et al., 2013) as modern training set to be compared with our high-altitude fossil site. The EMPD dataset is valuable in that it provides a large geographic coverage of main ecological and climate gradients (at sub-continental scale) but lacks in sampling of altitudinal gradients and high-altitude sites in the Alps. We therefore designed an independent altitudinal training set for the alpine valley hosting our fossil site. 27 sampling plots were selected along a 1700m-elevational transect. In a first step, each plot was provided with (i) 3 moss polsters collected following the guidelines provided by Cañellas-Boltà et al. (2009) and analyzed separately to account for differences in pollen deposition at small scale, (ii) morphometrical parameters obtained through a high-resolution DEM, and (iii) temperature and precipitation were estimated by means of weighted linear regression of the meteorological variable versus elevation, locally evaluated for each site (Brunetti et al

  17. Rhodiola crenulata- and Cordyceps sinensis-based supplement boosts aerobic exercise performance after short-term high altitude training.

    Science.gov (United States)

    Chen, Chung-Yu; Hou, Chien-Wen; Bernard, Jeffrey R; Chen, Chiu-Chou; Hung, Ta-Cheng; Cheng, Lu-Ling; Liao, Yi-Hung; Kuo, Chia-Hua

    2014-09-01

    High altitude training is a widely used strategy for improving aerobic exercise performance. Both Rhodiola crenulata (R) and Cordyceps sinensis (C) supplements have been reported to improve exercise performance. However, it is not clear whether the provision of R and C during high altitude training could further enhance aerobic endurance capacity. In this study, we examined the effect of R and C based supplementation on aerobic exercise capacity following 2-week high altitude training. Alterations to autonomic nervous system activity, circulatory hormonal, and hematological profiles were investigated. Eighteen male subjects were divided into two groups: Placebo (n=9) and R/C supplementation (RC, n=9). Both groups received either RC (R: 1400 mg+C: 600 mg per day) or the placebo during a 2-week training period at an altitude of 2200 m. After 2 weeks of altitude training, compared with Placebo group, the exhaustive run time was markedly longer (Placebo: +2.2% vs. RC: +5.7%; paltitude training (paltitude training provides greater training benefits in improving aerobic performance. This beneficial effect of RC treatment may result from better maintenance of PNS activity and accelerated physiological adaptations during high altitude training.

  18. Carbon storage and long-term rate of accumulation in high-altitude Andean peatlands of Bolivia

    Science.gov (United States)

    J.A. Hribljan; D.J. Cooper; J. Sueltenfuss; E.C. Wolf; K.A. Heckman; Erik Lilleskov; R.A. Chimner

    2015-01-01

    The high-altitude (4,500+ m) Andean mountain range of north-western Bolivia contains many peatlands. Despite heavy grazing pressure and potential damage from climate change, little is known about these peatlands. Our objective was to quantify carbon pools, basal ages and long-term peat accumulation rates in peatlands in two areas of the arid puna ecoregion of Bolivia:...

  19. The Late-Glacial and Holocene Marboré Lake sequence (2612 m a.s.l., Central Pyrenees, Spain): Testing high altitude sites sensitivity to millennial scale vegetation and climate variability

    Science.gov (United States)

    Leunda, Maria; González-Sampériz, Penélope; Gil-Romera, Graciela; Aranbarri, Josu; Moreno, Ana; Oliva-Urcia, Belén; Sevilla-Callejo, Miguel; Valero-Garcés, Blas

    2017-10-01

    This paper presents the environmental, climate and vegetation changes reconstructed for the last 14.6 kyr cal BP from the Marboré Lake sedimentary sequence, the highest altitude record (2612 m a.s.l.) in the Pyrenees studied up to date. We investigate the sensitivity of this high altitude site to vegetational and climate dynamics and altitudinal shifts during the Holocene by comparing palynological spectra of the fossil sequence and pollen rain content from current moss pollsters. We hypothesize that the input of sediments in lakes at such altitude is strongly controlled by ice phenology (ice-free summer months) and that during cold periods Pollen Accumulation Rate (PAR) and Pollen Concentration (PC) reflect changes in ice-cover and thus is linked to temperature changes. Low sedimentation rates and low PC and PAR occurred during colder periods as the Younger Dryas (GS-1) and the Holocene onset (12.6-10.2 kyr cal BP), suggesting that the lake-surface remained ice-covered for most of the year during these periods. Warmer conditions are not evident until 10.2 kyr cal BP, when an abrupt increase in sedimentation rate, PC and PAR occur, pointing to a delayed onset of the Holocene temperature increase at high altitude. Well-developed pinewoods and deciduous forest dominated the mid montane belt since 9.3 kyr cal BP until mid-Holocene (5.2 kyr cal BP). A downwards shift in the deciduous forest occurred after 5.2 kyr cal BP, in agreement with the aridity trend observed at a regional and Mediterranean context. The increase of herbaceous taxa during the late-Holocene (3.5 kyr cal BP-present) reflects a general trend to reduced montane forest, as anthropogenic disturbances were not evident until 1.3 kyr cal BP when Olea proportions from lowland areas and other anthropogenic indicators clearly expand. Our study demonstrates the need to perform local experimental approaches to check the effect of ice phenology on high altitude lakes sensitivity to vegetation changes to obtain

  20. High altitude agriculture in the Titicaca basin (800 BCE-200 CE): Impacts on nutrition and disease load.

    Science.gov (United States)

    Juengst, Sara L; Hutchinson, Dale L; Chávez, Sergio J

    2017-07-08

    This study investigates the biological impacts of sedentism and agriculture on humans living in the high altitude landscape of the Titicaca Basin between 800 BCE and CE 200. The transition to agriculture in other global areas resulted in increases in disease and malnutrition; the high altitude of the Titicaca Basin could have exacerbated this. Our objective is to test whether the high altitude of the Titicaca Basin created a marginal environment for early agriculturalists living there, reflected through elevated rates of malnutrition and/or disease. To test this, we analyzed human remains excavated from seven archaeological sites on the Copacabana Peninsula for markers of diet and disease. These markers included dental caries, dental abscesses, cribra orbitalia, porotic hyperostosis, periosteal reactions, osteomyelitis, and linear enamel hypoplasia. Results showed that markers of diet did not support malnutrition or micronutrient deficiencies but instead, indicated a relatively diverse diet for all individuals. Markers of disease also did not vary significantly but were common, indicating circulation of pathogens or chronic bodily stress. We interpret these results as an indication that while diets remained nutritious, investment in the landscape exposed populations to issues of sanitation and disease. The high-altitude of the Titicaca Basin did not exacerbate the biological impacts of agriculture in terms of increased malnutrition. Additionally, disease load was likely related to problems faced by many sedentary groups as opposed to unique challenges posed by high altitude. In sum, despite the high elevation, the Titicaca Basin is not truly a marginal environment for humans. © 2017 Wiley Periodicals, Inc.

  1. Ionospheric plasma escape by high-altitude electric fields: Magnetic moment ''pumping''

    International Nuclear Information System (INIS)

    Lundin, R.; Hultqvist, B.

    1989-01-01

    Measurements of electric fields and the composition of upward flowing ionospheric ions by the Viking spacecraft have provided further insight into the mass dependent plasma escape process taking place in the upper ionosphere. The Viking results of the temperature and mass-composition of individual ion beams suggest that upward flowing ion beams can be generated by a magnetic moment ''pumping'' mechanism caused by low-frequency transverse electric field fluctuations, in addition to a field aligned ''quasi-electrostatic'' acceleration process. Magnetic moment ''pumping'' within transverse electric field gradients can be described as a conversion of electric drift velocity to cyclotron velocity by the inertial drift in time-dependent electric field. This gives an equal cyclotron velocity gain for all plasma species, irrespective of mass. Oxygen ions thus gain 16 times as much transverse energy as protons. In addition to a transverse energy gain above the escape energy, a field-aligned quasi-electrostatic acceleration is considered primarily responsible for the collimated upward flow of ions. The field-aligned acceleration adds a constant parallel energy to escaping ionospheric ions. Thus, ion beams at high altitudes can be explained by a bimodal acceleration from both a transverse (equal velocity) and a parallel (equal energy) acceleration process. The Viking observations also show that the thermal energy of ion beams, and the ion beam width are mass dependent. The average O + /H + ''temperature ratio has been found to be 4.0 from the Viking observations. This is less than the factor of 16 anticipated from a coherent transverse electric field acceleration but greater than the factor of 1 (or even less than 1) expected from a turbulent acceleration process. copyright American Geophysical Union 1989

  2. Using High-Altitude Pseudo Satellites as an innovative technology platform for climate measurements

    Science.gov (United States)

    Coulon, A.; Johnson, S.

    2017-12-01

    Climate scientists have been using for decades either remotely observed data, mainly from (un)manned aircraft and satellites, or ground-based measurements. High-Altitude Pseudo Satellites (HAPS) are emerging as a disruptive technology that will be used for various "Near Space" applications at altitudes between 15 and 23 km (i.e. above commercial airlines). This new generation of electric solar-powered unmanned aerial vehicles flying in the stratosphere aim to persistently monitor regional areas (with high temporal, spatial and spectral resolution) as well as perform in-situ Near Space observations. The two case studies presented will highlight the advantages of using such an innovative platform. First, calculations were performed to compare the use of a constellation of Low Earth Orbit satellites and a fleet of HAPS for surface monitoring. Using stratospheric drones has a clear advantage for revisiting a large zone (10'000km2 per day) with higher predictability and accuracy. User is free to set time over a location, avoid cloud coverage and obtain Ground Sampling Distance of 30cm using commercially of the shelf sensors. The other impact study focuses on in-situ measurements. Using HAPS will indeed help to closely observe stratospheric compounds, such as aerosols or volcano plumes. Simulations were performed to show how such a drone could collect samples and provide high-accuracy evaluations of compounds that, so far, are only remotely observed. The performed impact studies emphasize the substantial advantages of using HAPS for future stratospheric campaigns. Deploying month-long unmanned missions for monitoring stratospheric aerosols will be beneficial for future research projects such as climate engineering.

  3. A new TDRSS Compatible Transceiver for Long Duration HIgh Altitude Scientific Balloon Missions

    Science.gov (United States)

    Stilwell, B.; Siemon, M.

    High altitude scientific balloons have been used for many years to provide scientists with access to near space at a fraction of the cost of satellite based or sounding rocket experiments. In recent years, these balloons have been successfully used for long duration missions of up to several weeks. Longer missions with durations of up to 100 days (Ultra-Long) are on the drawing board. An enabling technology for the growth of the scientific balloon missions is the use of the NASA Tracking and Data Relay Satellite System (TDRSS) for telemetering the health, status, position and payload science data to mission operations personnel. The TDRSS system provides global coverage by relaying the data through geostationary relay satellites to a single ground station in White Sands New Mexico. Data passes from the White Sands station to the user via commercial telecommunications services including the Internet. A forward command link can also be established to the balloon for real- time command and control. Early TDRSS communications equipment used by the National Scientific Balloon Facility was either unreliable or too expensive. The equipment must be a le tob endure the rigors of space flight including radiation exposure, high temperature extremes and the shock of landing and recovery. Since a payload may occasionally be lost, the cost of the TDRSS communications gear is a limiting factor in the number of missions that can be supported. Under sponsorship of the NSBF, General Dynamics Decision Systems has developed a new TDRSS compatible transceiver that reduces the size, weight and cost to approximately one half that of the prior generation of hardware. This paper describes the long and ultra-long balloon missions and the role that TDRSS communications plays in mission success. The new transceiver design is described, along with its interfaces, performance characteristics, qualification and production status. The transceiver can also be used in other space, avionics or

  4. PHOTOIONIZATION OF HIGH-ALTITUDE GAS IN A SUPERNOVA-DRIVEN TURBULENT INTERSTELLAR MEDIUM

    International Nuclear Information System (INIS)

    Wood, Kenneth; Hill, Alex S.; Haffner, L. Matthew; Reynolds, R. J.; Joung, M. Ryan; Mac Low, Mordecai-Mark; Benjamin, Robert A.; Madsen, G. J.

    2010-01-01

    We investigate models for the photoionization of the widespread diffuse ionized gas (DIG) in galaxies. In particular, we address the long standing question of the penetration of Lyman continuum photons from sources close to the galactic midplane to large heights in the galactic halo. We find that recent hydrodynamical simulations of a supernova-driven interstellar medium (ISM) have low-density paths and voids that allow for ionizing photons from midplane OB stars to reach and ionize gas many kiloparsecs above the midplane. We find that ionizing fluxes throughout our simulation grids are larger than predicted by one-dimensional slab models, thus allowing for photoionization by O stars of low altitude neutral clouds in the Galaxy that are also detected in Hα. In previous studies of such clouds, the photoionization scenario had been rejected and the Hα had been attributed to enhanced cosmic ray ionization or scattered light from midplane H II regions. We do find that the emission measure distributions in our simulations are wider than those derived from Hα observations in the Milky Way. In addition, the horizontally averaged height dependence of the gas density in the hydrodynamical models is lower than inferred in the Galaxy. These discrepancies are likely due to the absence of magnetic fields in the hydrodynamic simulations and we discuss how magnetohydrodynamic effects may reconcile models and observations. Nevertheless, we anticipate that the inclusion of magnetic fields in the dynamical simulations will not alter our primary finding that midplane OB stars are capable of producing high-altitude DIG in a realistic three-dimensional ISM.

  5. Genome wide expression analysis suggests perturbation of vascular homeostasis during high altitude pulmonary edema.

    Directory of Open Access Journals (Sweden)

    Manish Sharma

    Full Text Available BACKGROUND: High altitude pulmonary edema (HAPE is a life-threatening form of non-cardiogenic edema which occurs in unacclimatized but otherwise normal individuals within two to four days after rapid ascent to altitude beyond 3000 m. The precise pathoetiology and inciting mechanisms regulating HAPE remain unclear. METHODOLOGY/PRINCIPLE FINDINGS: We performed global gene expression profiling in individuals with established HAPE compared to acclimatized individuals. Our data suggests concurrent modulation of multiple pathways which regulate vascular homeostasis and consequently lung fluid dynamics. These pathways included those which regulate vasoconstriction through smooth muscle contraction, cellular actin cytoskeleton rearrangements and endothelial permeability/dysfunction. Some notable genes within these pathways included MYLK; rho family members ARGEF11, ARHGAP24; cell adhesion molecules such as CLDN6, CLDN23, PXN and VCAM1 besides other signaling intermediates. Further, several important regulators of systemic/pulmonary hypertension including ADRA1D, ECE1, and EDNRA were upregulated in HAPE. We also observed significant upregulation of genes involved in paracrine signaling through chemokines and lymphocyte activation pathways during HAPE represented by transcripts of TNF, JAK2, MAP2K2, MAP2K7, MAPK10, PLCB1, ARAF, SOS1, PAK3 and RELA amongst others. Perturbation of such pathways can potentially skew vascular homeostatic equilibrium towards altered vascular permeability. Additionally, differential regulation of hypoxia-sensing, hypoxia-response and OXPHOS pathway genes in individuals with HAPE were also observed. CONCLUSIONS/SIGNIFICANCE: Our data reveals specific components of the complex molecular circuitry underlying HAPE. We show concurrent perturbation of multiple pathways regulating vascular homeostasis and suggest multi-genic nature of regulation of HAPE.

  6. Aquatic life at high altitude: respiratory adaptations in the Lake Titicaca frog, Telmatobius culeus.

    Science.gov (United States)

    Hutchison, V H; Haines, H B; Engbretson, G

    1976-07-01

    Telmatobius culeus has a combination of behavioral, morphological and physiological adaptations which allows an aquatic life in cool (10 degrees C) O2-saturated (at 100 mm Hg) waters at high altitude (3812 m). The skin surgace area is increased by pronounced folds and the cutaneous capillaries penetrate to the outer layers of the skin. The erythrocyte volume (394 mu3) is the smallest reported for amphibians. The P50 (15.6 at ph 7.65 and 10 degrees C) is the lowest, and the erythrocyte count (729 - 103/mm3) the highest for an anuran. The O2 capacity (11.7 vol%), hemoglobin (8.1 g/100 ml), hemoglobin concentration (0.281 pg/mu3) and hematocrit (27.9%) measured at 18 degrees C and 3800 m are all elevated in comparison with most amphibians. The O2 dissociation curve is sigmoid (n = 2), the Bohr factor is small (deltalog P50/deltapH = -0.30) and the buffering capacity (-8.9 m M HCO3 - 1-1) is typical for an aquatic amphibian. The metabolic rate (14.1 mul -g-1-h-u) is the lowest reported for a frog and among amphibians only the giant salamanders (Amphiuma, Necturus and Siren) have lower values. If prevent from surfacing in hypoxic waters, the frogs ventilate the skin by "bobbing" behavior; if allowed to surface, they will ventilate the small lungs and the metabolic rate increases to 23 mul-g-1-h-1.

  7. Investigation of thermoelastic stresses induced at high altitudes on aircraft external fuel tanks

    Science.gov (United States)

    Mousseau, Stephanie Lynn Steber

    As composite technology has grown over the past several decades, the use of composite materials in military applications has become more feasible and widely accepted. Although composite materials provide many benefits, including strength optimization and reduced weight, damage and repair of these materials creates an additional challenge, especially when operating in a marine environment, such as on a carrier deck. This is evident within the Navy, as excessive damage often leads to the scrapping of F/A-18 External Fuel Tanks. This damage comes in many forms, the most elusive of which is delamination. Often the delamination found on the tanks is beyond repairable limits and the cause unknown, making it difficult to predict and prevent. The purpose of this investigation was to study the structure of the Navy's 330 gallon External Fuel Tanks and investigate one potential cause of delamination, stresses induced at high altitudes by cold temperatures. A stress analysis was completed using finite element software, and validation of the model was accomplished through testing of a scale model specimen. Due to the difficulties in modeling and predicting delamination, such as unknown presence of voids and understanding failure criteria, delamination was not modeled in Abaqus, rather stresses were observed and characteristics were studied to understand the potential for delamination within the layup. In addition, studies were performed to understand the effect of material properties and layup sequence on the stress distribution within the tank. Alternative design solutions are presented which could reduce the radial stresses within the tank, and recommendations are made for further study to understand the trade-offs between stress, cost, and manufacturability.

  8. The Effect of Sex on Heart Rate Variability at High Altitude.

    Science.gov (United States)

    Boos, Christopher John; Vincent, Emma; Mellor, Adrian; O'Hara, John; Newman, Caroline; Cruttenden, Richard; Scott, Phylip; Cooke, Mark; Matu, Jamie; Woods, David Richard

    2017-12-01

    There is evidence suggesting that high altitude (HA) exposure leads to a fall in heart rate variability (HRV) that is linked to the development of acute mountain sickness (AMS). The effects of sex on changes in HRV at HA and its relationship to AMS are unknown. HRV (5-min single-lead ECG) was measured in 63 healthy adults (41 men and 22 women) 18-56 yr of age at sea level (SL) and during a HA trek at 3619, 4600, and 5140 m, respectively. The main effects of altitude (SL, 3619 m, 4600 m, and 5140 m) and sex (men vs women) and their potential interaction were assessed using a factorial repeated-measures ANOVA. Logistic regression analyses were performed to assess the ability of HRV to predict AMS. Men and women were of similar age (31.2 ± 9.3 vs 31.7 ± 7.5 yr), ethnicity, and body and mass index. There was main effect for altitude on heart rate, SD of normal-to-normal (NN) intervals (SDNN), root mean square of successive differences (RMSSD), number of pairs of successive NN differing by >50 ms (NN50), NN50/total number of NN, very low-frequency power, low-frequency (LF) power, high-frequency (HF) power, and total power (TP). The most consistent effect on post hoc analysis was reduction in these HRV measures between 3619 and 5140 m at HA. Heart rate was significantly lower and SDNN, RMSSD, LF power, HF power, and TP were higher in men compared with women at HA. There was no interaction between sex and altitude for any of the HRV indices measured. HRV was not predictive of AMS development. Increasing HA leads to a reduction in HRV. Significant differences between men and women emerge at HA. HRV was not predictive of AMS.

  9. On the capabilities and limitations of high altitude pseudo-satellites

    Science.gov (United States)

    Gonzalo, Jesús; López, Deibi; Domínguez, Diego; García, Adrián; Escapa, Alberto

    2018-04-01

    The idea of self-sustaining air vehicles that excited engineers in the seventies has nowadays become a reality as proved by several initiatives worldwide. High altitude platforms, or Pseudo-satellites (HAPS), are unmanned vehicles that take advantage of weak stratospheric winds and solar energy to operate without interfering with current commercial aviation and with enough endurance to provide long-term services as satellites do. Target applications are communications, Earth observation, positioning and science among others. This paper reviews the major characteristics of stratospheric flight, where airplanes and airships will compete for best performance. The careful analysis of involved technologies and their trends allow budget models to shed light on the capabilities and limitations of each solution. Aerodynamics and aerostatics, structures and materials, propulsion, energy management, thermal control, flight management and ground infrastructures are the critical elements revisited to assess current status and expected short-term evolutions. Stratospheric airplanes require very light wing loading, which has been demonstrated to be feasible but currently limits their payload mass to few tenths of kilograms. On the other hand, airships need to be large and operationally complex but their potential to hover carrying hundreds of kilograms with reasonable power supply make them true pseudo-satellites with enormous commercial interest. This paper provides useful information on the relative importance of the technology evolutions, as well as on the selection of the proper platform for each application or set of payload requirements. The authors envisage prompt availability of both types of HAPS, aerodynamic and aerostatic, providing unprecedented services.

  10. Influence of high-altitude grazing on bone metabolism of growing sheep.

    Science.gov (United States)

    Liesegang, A; Hüttenmoser, D; Risteli, J; Leiber, F; Kreuzer, M; Wanner, M

    2013-02-01

    The objective of this study was to identify the effect of high alpine grazing, associated with varying pasture grass qualities and more pronounced exercise on typically steep slopes, on bone metabolism by improving bone density and enhancing bone turnover in growing sheep. Twenty-four 5-month-old sheep were randomly assigned to two groups. One group was kept at high altitude (HA; 2000-2200 m a.s.l.) for 3 months, and the other group (C; control) remained in the lowlands (400 m a.s.l.). Both groups were kept in grazing pastures with access to good-quality swards. Before the start of the experiment, blood samples were taken, the sheep were weighed, and the left metatarsus of each animal was analysed by quantitative computer tomography. After 1 month, blood samples were taken and body weight was measured, followed by biweekly sampling. Finally, the animals were slaughtered, and the bones were collected for analysis of various bone parameters. Body weight development did not differ between the groups. Concentrations of 25-OH-Vitamin D, carboxy-terminal telopeptide of type I collagen and activities of bone-specific alkaline phosphatase were always higher in the HA group than in the C group, except on the last two sampling dates. Bone mineral content and density increased in both groups during the experiment, but more intensively in the HA group. In addition, the cortical thickness of the HA group increased. The present study demonstrates an increase in bone turnover and mineral content of the bones of the growing sheep grazing in high alpine pastures. The factors associated with HA grazing, therefore, clearly seem to improve bone composition. © 2011 Blackwell Verlag GmbH.

  11. Feasibility of cord blood bank in high altitude Abha: preclinical impacts.

    Science.gov (United States)

    Chandramoorthy, Harish C; Bajunaid, Abdulmajeed Mohammed; Kariri, Hussian Nasser; Al-Hakami, Ahmed; Sham, Abdullah Abu; Al-Shahrani, Misfer Bin Safer; Al-Humayed, Suliman M; Rajagopalan, Prasanna

    2018-02-19

    We explored the possibility of the cryo-storage of cord blood hematopoietic stem cells (CBHPSC) with respect to the quantity, quality and biologic efficacy of high altitude (HA) region Abha against sea level (SL) region. The results of the post-processed total nucleated cell count was 8.03 ± 0.31 × 10 7 and 8.44 ± 0.23 × 10 7 cells in the HA and SL regions respectively. The mean post processing viability of the nucleated cells was about 87.03 ± 1.39 (HA) and 88.33 ± 1.55% (SL) while post thaw cells were 85.61 ± 1.44 (HA) and 86.58 ± 1.61% (SL) after transient cryo-storage. The proliferation of CBHSCs after thawing were comparable between the HA and SL regions. The results of the colony forming unit (CFU) assays of CFU-E, CFU-GEMM, CFU-GM and BFU-E were comparable between HA and SL in both fresh and post thaw, while a declining trend with viability was significant. The differentiation capability of post thaw samples into adipocytes and osteocytes were comparable between HA and SL regions. Overall from the results, it can be evidenced that HA cord blood collection, processing or storage does not hinder the quality or biological efficacy of the CBHPSC.

  12. Adaptive modulation of adult brain gray and white matter to high altitude: structural MRI studies.

    Directory of Open Access Journals (Sweden)

    Jiaxing Zhang

    Full Text Available The aim of this study was to investigate brain structural alterations in adult immigrants who adapted to high altitude (HA. Voxel-based morphometry analysis of gray matter (GM volumes, surface-based analysis of cortical thickness, and Tract-Based Spatial Statistics analysis of white matter fractional anisotropy (FA based on MRI images were conducted on 16 adults (20-22 years who immigrated to the Qinghai-Tibet Plateau (2300-4400 m for 2 years. They had no chronic mountain sickness. Control group consisted of 16 matched sea level subjects. A battery of neuropsychological tests was also conducted. HA immigrants showed significantly decreased GM volumes in the right postcentral gyrus and right superior frontal gyrus, and increased GM volumes in the right middle frontal gyrus, right parahippocampal gyrus, right inferior and middle temporal gyri, bilateral inferior ventral pons, and right cerebellum crus1. While there was some divergence in the left hemisphere, surface-based patterns of GM changes in the right hemisphere resembled those seen for VBM analysis. FA changes were observed in multiple WM tracts. HA immigrants showed significant impairment in pulmonary function, increase in reaction time, and deficit in mental rotation. Parahippocampal and middle frontal GM volumes correlated with vital capacity. Superior frontal GM volume correlated with mental rotation and postcentral GM correlated with reaction time. Paracentral lobule and frontal FA correlated with mental rotation reaction time. There might be structural modifications occurred in the adult immigrants during adaptation to HA. The changes in GM may be related to impaired respiratory function and psychological deficits.

  13. Aerosol chemistry over a high altitude station at northeastern Himalayas, India.

    Directory of Open Access Journals (Sweden)

    Abhijit Chatterjee

    Full Text Available BACKGROUND: There is an urgent need for an improved understanding of the sources, distributions and properties of atmospheric aerosol in order to control the atmospheric pollution over northeastern Himalayas where rising anthropogenic interferences from rapid urbanization and development is becoming an increasing concern. METHODOLOGY/PRINCIPAL FINDINGS: An extensive aerosol sampling program was conducted in Darjeeling (altitude approximately 2200 meter above sea level (masl, latitude 27 degrees 01'N and longitude 88 degrees 15'E, a high altitude station in northeastern Himalayas, during January-December 2005. Samples were collected using a respirable dust sampler and a fine dust sampler simultaneously. Ion chromatograph was used to analyze the water soluble ionic species of aerosol. The average concentrations of fine and coarse mode aerosol were found to be 29.5+/-20.8 microg m(-3 and 19.6+/-11.1 microg m(-3 respectively. Fine mode aerosol dominated during dry seasons and coarse mode aerosol dominated during monsoon. Nitrate existed as NH(4NO(3 in fine mode aerosol during winter and as NaNO(3 in coarse mode aerosol during monsoon. Gas phase photochemical oxidation of SO(2 during premonsoon and aqueous phase oxidation during winter and postmonsoon were the major pathways for the formation of SO(4(2- in the atmosphere. Long range transport of dust aerosol from arid regions of western India was observed during premonsoon. The acidity of fine mode aerosol was higher in dry seasons compared to monsoon whereas the coarse mode acidity was higher in monsoon compared to dry seasons. Biomass burning, vehicular emissions and dust particles were the major types of aerosol from local and continental regions whereas sea salt particles were the major types of aerosol from marine source regions. CONCLUSIONS/SIGNIFICANCE: The year-long data presented in this paper provide substantial improvements to the heretofore poor knowledge regarding aerosol chemistry over

  14. Aerosol chemistry over a high altitude station at northeastern Himalayas, India.

    Science.gov (United States)

    Chatterjee, Abhijit; Adak, Anandamay; Singh, Ajay K; Srivastava, Manoj K; Ghosh, Sanjay K; Tiwari, Suresh; Devara, Panuganti C S; Raha, Sibaji

    2010-06-16

    There is an urgent need for an improved understanding of the sources, distributions and properties of atmospheric aerosol in order to control the atmospheric pollution over northeastern Himalayas where rising anthropogenic interferences from rapid urbanization and development is becoming an increasing concern. An extensive aerosol sampling program was conducted in Darjeeling (altitude approximately 2200 meter above sea level (masl), latitude 27 degrees 01'N and longitude 88 degrees 15'E), a high altitude station in northeastern Himalayas, during January-December 2005. Samples were collected using a respirable dust sampler and a fine dust sampler simultaneously. Ion chromatograph was used to analyze the water soluble ionic species of aerosol. The average concentrations of fine and coarse mode aerosol were found to be 29.5+/-20.8 microg m(-3) and 19.6+/-11.1 microg m(-3) respectively. Fine mode aerosol dominated during dry seasons and coarse mode aerosol dominated during monsoon. Nitrate existed as NH(4)NO(3) in fine mode aerosol during winter and as NaNO(3) in coarse mode aerosol during monsoon. Gas phase photochemical oxidation of SO(2) during premonsoon and aqueous phase oxidation during winter and postmonsoon were the major pathways for the formation of SO(4)(2-) in the atmosphere. Long range transport of dust aerosol from arid regions of western India was observed during premonsoon. The acidity of fine mode aerosol was higher in dry seasons compared to monsoon whereas the coarse mode acidity was higher in monsoon compared to dry seasons. Biomass burning, vehicular emissions and dust particles were the major types of aerosol from local and continental regions whereas sea salt particles were the major types of aerosol from marine source regions. The year-long data presented in this paper provide substantial improvements to the heretofore poor knowledge regarding aerosol chemistry over northeastern Himalayas, and should be useful to policy makers in making control

  15. Differences in physical growth of Aymara and Quechua children living at high altitude in Peru.

    Science.gov (United States)

    de Meer, K; Bergman, R; Kusner, J S; Voorhoeve, H W

    1993-01-01

    Physical growth of Amerindian children living in two Aymara and three Quechua peasant communities in the Andean highlands of southern Peru (altitude 3,810-3,840 m) was studied, taking into account differences in the microclimate, agronomic situation, and sociodemographic variables. Anthropometric measurements were taken in 395 children aged under 14 years of age in a sample of 151 families in these communities, who were surveyed for sociodemographic variables as well. Data on the land system were available for 77 families. In comparison with reference populations from the United States (NCHS) and The Netherlands, stature, weight, head circumference, and midupper arm circumference (but not weight for stature) in the sample children were reduced. Growth retardation increased after the age of 1 year. Stature and weight in the present sample were very similar compared with previously published data on growth of rural Aymara children living near Lake Titicaca in Bolivia. Head circumference, midupper arm circumference, and weight for stature were significantly larger in Aymara children compared with Quechua children. Land was significantly more fragmented in Aymara compared with Quechua families, but amount of land owned was not different. Perinatal and infant mortality was elevated in Aymara vs. Quechua communities. Most families in Aymara communities used protected drinking water. One Quechua community had a severe microclimate, grim economic outlook, and weak social cohesion. Children in this community showed significant reductions in weight and midupper arm circumference compared with their peers in the other communities. We conclude that (presumably nutritionally mediated) intervillage and Aymara-Quechua differences in childhood physical growth existed in this rural high-altitude population in Peru and were associated with microclimate and the village economy, sociodemographic factors, and differences in the land system.

  16. Supercharging system behavior for high altitude operation of an aircraft 2-stroke Diesel engine

    International Nuclear Information System (INIS)

    Carlucci, Antonio Paolo; Ficarella, Antonio; Laforgia, Domenico; Renna, Alessandro

    2015-01-01

    Highlights: • Different supercharging architectures have been compared for an aircraft 2T engine. • The supercharging architectures are compared to minimize the fuel consumption. • The architecture with the highest conversion efficiency was determined. - Abstract: Different studies on both 2- and 4-stroke engines have shown how the choice of different supercharging architectures can influence engine performance. Among them, architectures coupling one turbocharger with a mechanical compressor or two turbochargers are found to be the most performing in terms of engine output power and efficiency. However, defining the best supercharging architecture for aircraft 2-stroke engines is a quite complex task because the supercharging system as well as the ambient conditions influence the engine performance/efficiency. This is due to the close interaction between supercharging, trapping, scavenging and combustion processes. The aim of the present work is the comparison between different architectures (single turbocharger, double turbocharger, single turbocharger combined with a mechanical compressor, single turbocharger with an electrically-assisted turbocharger, with intercooler or aftercooler) designed to supercharge an aircraft 2-stroke Diesel engine for general aviation and unmanned aerial vehicles characterized by a very high altitude operation and long fuel distance. A 1D model of the engine purposely designed has been used to compare the performance of the different supercharging systems in terms of power, fuel consumption, and their effect on trapping and scavenging efficiency at different altitudes. The analysis shows that the engine target power is reached by a 2 turbochargers architecture; in this way, in fact, the cylinder filling, and consequently the engine performance, are maximized. Moreover, it is shown that the performance of a 2 turbochargers architecture performance can be further improved connecting electrically and not mechanically the low

  17. Cluster survey of the high-altitude cusp properties: a three-year statistical study

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    B. Lavraud

    2004-09-01

    Full Text Available The global characteristics of the high-altitude cusp and its surrounding regions are investigated using a three-year statistical survey based on data obtained by the Cluster spacecraft. The analysis involves an elaborate orbit-sampling methodology that uses a model field and takes into account the actual solar wind conditions and level of geomagnetic activity. The spatial distribution of the magnetic field and various plasma parameters in the vicinity of the low magnetic field exterior cusp are determined and it is found that: 1 The magnetic field distribution shows the presence of an intermediate region between the magnetosheath and the magnetosphere: the exterior cusp, 2 This region is characterized by the presence of dense plasma of magnetosheath origin; a comparison with the Tsyganenko (1996 magnetic field model shows that it is diamagnetic in nature, 3 The spatial distributions show that three distinct boundaries with the lobes, the dayside plasma sheet and the magnetosheath surround the exterior cusp, 4 The external boundary with the magnetosheath has a sharp bulk velocity gradient, as well as a density decrease and temperature increase as one goes from the magnetosheath to the exterior cusp, 5 While the two inner boundaries form a funnel, the external boundary shows no clear indentation, 6 The plasma and magnetic pressure distributions suggest that the exterior cusp is in equilibrium with its surroundings in a statistical sense, and 7 A preliminary analysis of the bulk flow distributions suggests that the exterior cusp is stagnant under northward IMF conditions but convective under southward IMF conditions.

  18. Estimating and forecasting the precipitable water vapor from GOES satellite data at high altitude sites

    Science.gov (United States)

    Marín, Julio C.; Pozo, Diana; Curé, Michel

    2015-01-01

    In this work, we describe a method to estimate the precipitable water vapor (PWV) from Geostationary Observational Environmental Satellite (GOES) data at high altitude sites. The method was applied at Atacama Pathfinder Experiment (APEX) and Cerro Toco sites, located above 5000 m altitude in the Chajnantor plateau, in the north of Chile. It was validated using GOES-12 satellite data over the range 0-1.2 mm since submillimeter/millimeter astronomical observations are only useful within this PWV range. The PWV estimated from GOES and the Final Analyses (FNL) at APEX for 2007 and 2009 show root mean square error values of 0.23 mm and 0.36 mm over the ranges 0-0.4 mm and 0.4-1.2 mm, respectively. However, absolute relative errors of 51% and 33% were shown over these PWV ranges, respectively. We recommend using high-resolution thermodynamic profiles from the Global Forecast System (GFS) model to estimate the PWV from GOES data since they are available every three hours and at an earlier time than the FNL data. The estimated PWV from GOES/GFS agrees better with the observed PWV at both sites during night time. The largest errors are shown during daytime. Short-term PWV forecasts were implemented at both sites, applying a simple persistence method to the PWV estimated from GOES/GFS. The 12 h and 24 h PWV forecasts evaluated from August to October 2009 indicates that 25% of them show a very good agreement with observations whereas 50% of them show reasonably good agreement with observations. Transmission uncertainties calculated for PWV estimations and forecasts over the studied sites are larger over the range 0-0.4 mm than over the range 0.4-1.2 mm. Thus, the method can be used over the latter interval with more confidence.

  19. High-Energy Astrophysics with the High Altitude Water Cherenkov (HAWC) Observatory

    Science.gov (United States)

    Pretz, John; HAWC Collaboration

    2013-04-01

    The High Altitude Water Cherenkov (HAWC) observatory, under construction at Sierra Negra in the state of Puebla, Mexico, consists of a 22500 square meter area of water Cherenkov detectors: water tanks instrumented with light-sensitive photomultiplier tubes. The experiment is used to detect energetic secondary particles reaching the ground when a 50 GeV to 100 TeV cosmic ray or gamma ray interacts in the atmosphere above the experiment. By timing the arrival of particles on the ground, the direction of the original primary particle may be resolved with an error of between 1.0 (50 GeV) and 0.1 (10 TeV) degrees. Gamma-ray primaries may be distinguished from cosmic ray background by identifying the penetrating particles characteristic of a hadronic particle shower. The instrument is 10% complete and is performing as expected, with 30% of the channels anticipated by the summer of 2013. HAWC will complement existing Imaging Atmospheric Cherenkov Telescopes and space-based gamma-ray telescopes with its extreme high-energy sensitivity and its large field-of-view. The observatory will be used to study particle acceleration in Pulsar Wind Nebulae, Supernova Remnants, Active Galactic Nuclei and Gamma-ray Bursts. Additionally, the instrument can be used to probe dark matter annihilation in halo and sub-halos of the galaxy. We will present the sensitivity of the HAWC instrument in the context of the main science objectives. We will also present the status of the deployment including first data from the instrument and prospects for the future.

  20. Experimental characterization of the COndensation PArticle counting System for high altitude aircraft-borne application

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    S. Borrmann

    2009-06-01

    Full Text Available A characterization of the ultra-fine aerosol particle counter COPAS (COndensation PArticle counting System for operation on board the Russian high altitude research aircraft M-55 Geophysika is presented. The COPAS instrument consists of an aerosol inlet and two dual-channel continuous flow Condensation Particle Counters (CPCs operated with the chlorofluorocarbon FC-43. It operates at pressures between 400 and 50 hPa for aerosol detection in the particle diameter (dp range from 6 nm up to 1 μm. The aerosol inlet, designed for the M-55, is characterized with respect to aspiration, transmission, and transport losses. The experimental characterization of counting efficiencies of three CPCs yields dp50 (50% detection particle diameter of 6 nm, 11 nm, and 15 nm at temperature differences (ΔT between saturator and condenser of 17°C, 30°C, and 33°C, respectively. Non-volatile particles are quantified with a fourth CPC, with dp50=11 nm. It includes an aerosol heating line (250°C to evaporate H2SO4-H2O particles of 11 nm<dp<200 nm at pressures between 70 and 300 hPa. An instrumental in-flight inter-comparison of the different COPAS CPCs yields correlation coefficients of 0.996 and 0.985. The particle emission index for the M-55 in the range of 1.4–8.4×1016 kg−1 fuel burned has been estimated based on measurements of the Geophysika's own exhaust.

  1. Toward High Altitude Airship Ground-Based Boresight Calibration of Hyperspectral Pushbroom Imaging Sensors

    Directory of Open Access Journals (Sweden)

    Aiwu Zhang

    2015-12-01

    Full Text Available The complexity of the single linear hyperspectral pushbroom imaging based on a high altitude airship (HAA without a three-axis stabilized platform is much more than that based on the spaceborne and airborne. Due to the effects of air pressure, temperature and airflow, the large pitch and roll angles tend to appear frequently that create pushbroom images highly characterized with severe geometric distortions. Thus, the in-flight calibration procedure is not appropriate to apply to the single linear pushbroom sensors on HAA having no three-axis stabilized platform. In order to address this problem, a new ground-based boresight calibration method is proposed. Firstly, a coordinate’s transformation model is developed for direct georeferencing (DG of the linear imaging sensor, and then the linear error equation is derived from it by using the Taylor expansion formula. Secondly, the boresight misalignments are worked out by using iterative least squares method with few ground control points (GCPs and ground-based side-scanning experiments. The proposed method is demonstrated by three sets of experiments: (i the stability and reliability of the method is verified through simulation-based experiments; (ii the boresight calibration is performed using ground-based experiments; and (iii the validation is done by applying on the orthorectification of the real hyperspectral pushbroom images from a HAA Earth observation payload system developed by our research team—“LanTianHao”. The test results show that the proposed boresight calibration approach significantly improves the quality of georeferencing by reducing the geometric distortions caused by boresight misalignments to the minimum level.

  2. Lung function and breathing pattern in subjects developing high altitude pulmonary edema.

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    Christian F Clarenbach

    Full Text Available INTRODUCTION: The purpose of the study was to comprehensively evaluate physiologic changes associated with development of high altitude pulmonary edema (HAPE. We tested whether changes in pulmonary function and breathing pattern would herald clinically overt HAPE at an early stage. METHODS: In 18 mountaineers, spirometry, diffusing capacity, nitrogen washout, nocturnal ventilation and pulse oximetry were recorded at 490 m and during 3 days after rapid ascent to 4559 m. Findings were compared among subjects developing HAPE and those remaining well (controls. RESULTS: In 8 subjects subsequently developing radiographically documented HAPE at 4559 m, median FVC declined to 82% of low altitude baseline while closing volume increased to 164% of baseline (P<0.05, both instances. In 10 controls, FVC decreased slightly (to 93% baseline, P<0.05 but significantly less than in subjects with HAPE and closing volume remained unchanged. Sniff nasal pressure was reduced in both subjects with and without subsequent HAPE. During nights at 4559 m, mean nocturnal oxygen saturation dropped to lower values while minute ventilation, the number of periodic breathing cycles and heart rate were higher (60%; 8.6 L/min; 97 cycles/h; 94 beats/min, respectively in subjects subsequently developing HAPE than in controls (73%; 5.1 L/min; 48 cycles/h; 79 beats/min; P<0.05 vs. HAPE, all instances. CONCLUSION: The results comprehensively represent the pattern of physiologic alterations that precede overt HAPE. The changes in lung function are consistent with reduced lung compliance and impaired gas exchange. Pronounced nocturnal hypoxemia, ventilatory control instability and sympathetic stimulation are further signs of subsequent overt HAPE.

  3. Long term picoplankton dynamics in a warm-monomictic, tropical high altitude lake

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    Alfonso LUGO VÁZQUEZ

    2009-08-01

    Full Text Available Long term analyses of the microbial loop, centred on the picoplankton dynamics, were carried out over a five-year (1998 to 2002 period in Lake Alchichica (Puebla, Mexico, a high altitude tropical athalassohaline lake. The hydrodynamics of the lake followed a warm-monomictic pattern with mixing at a minimum temperature during the early dry season while the stratification was pronounced in the late dry season and throughout the rainy season; anoxic conditions in the hypolimnion lasted <9 months. The annual mean concentrations of chlorophyll-a were below 4 μg L-1 in 1998, 1999 and 2001, however, 6.1 and 5.2 μg L-1 in 2000 and 2002, respectively. Total picoplankton, TPP, displayed a temporal pattern that followed the mixing-stratification cycle. The highest TPP values (the whole water column ≥5×106 cells mL-1 were found during mixing and early stratification (January-March. The minimum numbers were present during late stratification (October-November. The maximum TPP numbers were observed within the layer 0-20 m, which corresponded to the epilimnion during the stratification period. Neither the thermocline nor the deep chlorophyll maximum showed an elevated TPP concentration. In the hypolimnion, TPP numbers were low (frequently <1×106 cells mL-1 apparently as a result of the long period of anoxia. Notwithstanding autotrophic picoplankton (APP contributed even ≥30% of TPP (2001 to 2002; no significant correlation was found between TPP and chlorophyll-a.

  4. Efficacy of ibuprofen on prevention of high altitude headache: A systematic review and meta-analysis.

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    Juan Xiong

    Full Text Available Ibuprofen is used to prevent high altitude headache (HAH but its efficacy remains controversial. We conducted a systematic review and meta-analysis of randomized, placebo-controlled trials (RCTs of ibuprofen for the prevention of HAH.Studies reporting efficacy of ibuprofen for prevention of HAH were identified by searching electronic databases (until December 2016. The primary outcome was the difference in incidence of HAH between ibuprofen and placebo groups. Risk ratios (RR were aggregated using a Mantel-Haenszel random effect model. Heterogeneity of included trials was assessed using the I2 statistics.In three randomized-controlled clinical trials involving 407 subjects, HAH occurred in 101 of 239 subjects (42% who received ibuprofen and 96 of 168 (57% who received placebo (RR = 0.79, 95% CI 0.66 to 0.96, Z = 2.43, P = 0.02, I2 = 0%. The absolute risk reduction (ARR was 15%. Number needed to treat (NNT to prevent HAH was 7. Similarly, The incidence of severe HAH was significant in the two groups (RR = 0.40, 95% CI 0.17 to 0.93, Z = 2.14, P = 0.03, I2 = 0%. Severe HAH occurred in 3% treated with ibuprofen and 10% with placebo. The ARR was 8%. NNT to prevent severe HAH was 13. Headache severity using a visual analogue scale was not different between ibuprofen and placebo. Similarly, the difference between the two groups in the change in SpO2 from baseline to altitude was not different. One included RCT reported one participant with black stools and three participants with stomach pain in the ibuprofen group, while seven participants reported stomach pain in the placebo group.Based on a limited number of studies ibuprofen seems efficacious for the prevention of HAH and may therefore represent an alternative for preventing HAH with acetazolamide or dexamethasone.

  5. High altitude induced anorexia: effect of changes in leptin and oxidative stress levels.

    Science.gov (United States)

    Vats, Praveen; Singh, Vijay Kumar; Singh, Som Nath; Singh, Shashi Bala

    2007-01-01

    High altitude (HA) exposure usually leads to a significant weight loss in non-acclimatized humans. Anorexia is believed to be the main cause of this body weight loss. Appetite regulatory peptides, i.e. leptin and neuropeptide Y play a key role in food intake and energy homeostasis. Recent studies suggests increased oxidative stress during HA exposure. In present study effect of HA exposure on levels of leptin and NPY was evaluated along with N-acetyl cysteine (NAC) and vitamin E supplementation in relation to food intake and body weight changes. The study was conducted on 30 healthy male volunteers (age 19-29 years). Subjects were divided randomly into three groups of 10 each. Group 1 (placebo) supplemented with 400 mg of calcium gluconate, group 2 and 3 were supplemented with 400 mg of NAC and 400 mg vitamin E, respectively per day. The study was conducted at low altitude (320 m, Phase I), at HA 3600 m (Phase II) and at an altitude of 4580 m (Phase III). On HA exposure significant reduction in plasma leptin levels was observed in all the groups on day 2 (Phase II) along with decrease in food intake and reduction in body weight. Statistically significant increase in blood malondialdehyde (MDA) levels was seen in all the groups on HA exposure (Phase II, Day 2), but the maximum increase was in case of placebo group (65.1%) on day 2 (Phase II) in comparison to low altitude values. The decrease in energy intake was almost same in all the groups indicating that antioxidant supplementation did not provide any protection against HA anorexia. From the study, it may be concluded that leptin and oxidative stress possibly are not the key players for HA anorexia.

  6. [Physical performance of older adults living in rural areas at sea level and at high altitude in Peru].

    Science.gov (United States)

    Estela-Ayamamani, David; Espinoza-Figueroa, Jossué; Columbus-Morales, Mauricio; Runzer-Colmenares, Fernando; Parodi, José F; Mayta-Tristán, Percy

    2015-01-01

    Living at high altitudes requires the inhabitants to adapt biologically and socially to the environment. The objective of this study was to determine the difference in physical performance (PP) in rural populations at sea level and at high altitude. A cross-sectional study was conducted in rural communities in Ancash, Peru, located at 3.345 meters above sea level (m.a.s.l.) and also in communities located in coastal areas at 6m.a.s.l. PP was measured by the Short Physical Performance Battery (SPPB) and other associated factors. Adjusted prevalence ratios (aPR) were calculated. A total of 130 older adults were assessed in the high altitude communities and 129 on the coast. The median age was 71.4 years, and 55.6% were female. Low physical performance (SPPB ≤ 6) was 10.0% at high altitude and 19.4% on the coast (p<0.05). Factors associated with low physical performance were residing at the coast (aPR: 2.10, 95% CI 1.02 to 4.33), self-reported poor health (aPR: 2.48, 95% CI 1.21 -5.08), hypertension (aPR: 1.73, 95% CI 1.01 to 2.98), and age (aPR: 1.04, 95% CI 1.01 to 1.07), while being a farmer (aPR: 0.49, 95% CI 0.25 to 0.97), and being independent (aPR: 0.37, 95% CI 0,20-, 072) were found to be protective factors. It was also found that the inhabitants of the coast have a mean of 0.86 points lower total SPPB than the high altitude ones (p=0.004). There is an association between altitude of residence and PP in older adults. The prevalence of a low PP in older adults in rural areas at sea level is twice as high compared to those living in high altitude rural communities. Copyright © 2014 SEGG. Published by Elsevier Espana. All rights reserved.

  7. High Altitude Affects Nocturnal Non-linear Heart Rate Variability: PATCH-HA Study

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    Christopher J. Boos

    2018-04-01

    Full Text Available Background: High altitude (HA exposure can lead to changes in resting heart rate variability (HRV, which may be linked to acute mountain sickness (AMS development. Compared with traditional HRV measures, non-linear HRV appears to offer incremental and prognostic data, yet its utility and relationship to AMS have been barely examined at HA. This study sought to examine this relationship at terrestrial HA.Methods: Sixteen healthy British military servicemen were studied at baseline (800 m, first night and over eight consecutive nights, at a sleeping altitude of up to 3600 m. A disposable cardiac patch monitor was used, to record the nocturnal cardiac inter-beat interval data, over 1 h (0200–0300 h, for offline HRV assessment. Non-linear HRV measures included Sample entropy (SampEn, the short (α1, 4–12 beats and long-term (α2, 13–64 beats detrend fluctuation analysis slope and the correlation dimension (D2. The maximal rating of perceived exertion (RPE, during daily exercise, was assessed using the Borg 6–20 RPE scale.Results: All subjects completed the HA exposure. The average age of included subjects was 31.4 ± 8.1 years. HA led to a significant fall in SpO2 and increase in heart rate, LLS and RPE. There were no significant changes in the ECG-derived respiratory rate or in any of the time domain measures of HRV during sleep. The only notable changes in frequency domain measures of HRV were an increase in LF and fall in HFnu power at the highest altitude. Conversely, SampEn, SD1/SD2 and D2 all fell, whereas α1 and α2 increased (p < 0.05. RPE inversely correlated with SD1/SD2 (r = -0.31; p = 0.002, SampEn (r = -0.22; p = 0.03, HFnu (r = -0.27; p = 0.007 and positively correlated with LF (r = 0.24; p = 0.02, LF/HF (r = 0.24; p = 0.02, α1 (r = 0.32; p = 0.002 and α2 (r = 0.21; p = 0.04. AMS occurred in 7/16 subjects (43.8% and was very mild in 85.7% of cases. HRV failed to predict AMS.Conclusion: Non-linear HRV is more sensitive to the

  8. An Undergraduate-Built Prototype Altitude Determination System (PADS) for High Altitude Research Balloons.

    Science.gov (United States)

    Verner, E.; Bruhweiler, F. C.; Abot, J.; Casarotto, V.; Dichoso, J.; Doody, E.; Esteves, F.; Morsch Filho, E.; Gonteski, D.; Lamos, M.; Leo, A.; Mulder, N.; Matubara, F.; Schramm, P.; Silva, R.; Quisberth, J.; Uritsky, G.; Kogut, A.; Lowe, L.; Mirel, P.; Lazear, J.

    2014-12-01

    In this project a multi-disciplinary undergraduate team from CUA, comprising majors in Physics, Mechanical Engineering, Electrical Engineering, and Biology, design, build, test, fly, and analyze the data from a prototype attitude determination system (PADS). The goal of the experiment is to determine if an inexpensive attitude determination system could be built for high altitude research balloons using MEMS gyros. PADS is a NASA funded project, built by students with the cooperation of CUA faculty, Verner, Bruhweiler, and Abot, along with the contributed expertise of researchers and engineers at NASA/GSFC, Kogut, Lowe, Mirel, and Lazear. The project was initiated through a course taught in CUA's School of Engineering, which was followed by a devoted effort by students during the summer of 2014. The project is an experiment to use 18 MEMS gyros, similar to those used in many smartphones, to produce an averaged positional error signal that could be compared with the motion of the fixed optical system as recorded through a string of optical images of stellar fields to be stored on a hard drive flown with the experiment. The optical system, camera microprocessor, and hard drive are enclosed in a pressure vessel, which maintains approximately atmospheric pressure throughout the balloon flight. The experiment uses multiple microprocessors to control the camera exposures, record gyro data, and provide thermal control. CUA students also participated in NASA-led design reviews. Four students traveled to NASA's Columbia Scientific Balloon Facility in Palestine, Texas to integrate PADS into a large balloon gondola containing other experiments, before being shipped, then launched in mid-August at Ft. Sumner, New Mexico. The payload is to fly at a float altitude of 40-45,000 m, and the flight last approximately 15 hours. The payload is to return to earth by parachute and the retrieved data are to be analyzed by CUA undergraduates. A description of the instrument is presented

  9. Peculiarities of high-altitude landscapes formation in the Small Caucasus mountains

    Science.gov (United States)

    Trifonova, Tatiana

    2014-05-01

    Various mountain systems differ in character of landscapes and soil. Basic problem of present research: conditions and parameters determining the development of various landscapes and soils in mountain areas. Our research object is the area of Armenia where Small Caucasus, a part of Armenian upland is located. The specific character of the area is defined by the whole variety of all mountain structures like fold, block folding mountain ridges, volcanic upland, individual volcanoes, and intermountain depressions. As for the climate, the area belongs to dry subtropics. We have studied the peculiarities of high-altitude landscapes formation and mountain river basins development. We have used remote sensing data and statistic database of climatic parameters in this research. Field observations and landscape pictures analysis of space images allow distinguishing three types of mountain geosystems clearly: volcanic massifs, fold mountainous structures and closed high mountain basins - area of the lakes. The distribution of precipitation according to altitude shows some peculiarities. It has been found that due to this factor the investigated mountain area may be divided into three regions: storage (fold) mountainous area; Ararat volcanic area (southern macro exposure); closed high mountainous basin-area of the lake Sevan. The mountainous nature-climatic vertical landscapes appear to be horizontally oriented and they are more or less equilibrium (stable) geosystems, where the stable functional relationship between the landscape components is formed. Within their limits, definite bioclimatic structure of soil is developed. Along the slopes of fold mountains specific landscape shapes like litho-drainage basins are formed. They are intensively developing like relatively independent vertical geosystems. Mechanism of basin formation is versatile resulting in formation of the polychronous soil mantle structure. Landscapes and soils within the basin are of a different age, since

  10. Ecological status of high altitude medicinal plants and their sustainability: Lingshi, Bhutan.

    Science.gov (United States)

    Lakey; Dorji, Kinley

    2016-10-11

    Human beings use plants for a multitude of purposes of which a prominent one across the globe is for their medicinal values. Medicinal plants serve as one of the major sources of income for high altitude inhabitants in the Himalaya, particularly in countries like Nepal, and Bhutan. People here harvest huge volumes of medicinal plants indiscriminately, risking their sustainability. This paper attempts to identify some of the priority medicinal plant species harvested in the wild and assess their ecological status for their judicious utilization, and to help provide policy guidance for possible domestication and support strategic conservation frameworks. Out of the 16 priority species identified by the expert group, collectors' perception on ecological status of the priority species differed from survey findings. Chrysosplenium nudicaule (clumps) ranked as most threatened species followed by Corydalis dubia, and Meconopsis simplicifolia. Onosma hookeri, Corydalis crispa and Delphinium glaciale were some of the species ranked as threatened species followed by Halenia elliptica (not in priority list). Percent relative abundance showed irregular pattern of species distribution. High species evenness was recorded among Nardostachys grandiflora, Chrysosplenium nudicaule, Saussurea gossypiphora and Aconitum orochryseum with average species density of 8 plant m -2 . Rhodiola crenulata, and Dactylorhiza hatagirea followed by Meconopsis horridula and Meconopsis simplicifolia were ranked as most threatened species with average species density of 0.4, 0.4, 5.6 and 6.0 plant m -2 , respectively. The most abundant (common) species was Onosma hookeri (plant m -2 ). Species composition and density also differed with vegetation, altitude, slope and its aspects. Priority species identified by expert group were found vulnerable and patchy in distribution. Survey results and collectors' perceptions tally to an extent. Some of the species (Dactylorhiza hatagirea, Rhodiola crenulata

  11. Long-Term Intermittent Exposure to High Altitude Elevates Asymmetric Dimethylarginine in First Exposed Young Adults.

    Science.gov (United States)

    Lüneburg, Nicole; Siques, Patricia; Brito, Julio; De La Cruz, Juan José; León-Velarde, Fabiola; Hannemann, Juliane; Ibanez, Cristian; Böger, Rainer H

    2017-09-01

    Lüneburg, Nicole, Patricia Siques, Julio Brito, Juan José De La Cruz, Fabiola León-Velarde, Juliane Hannemann, Cristian Ibanez, and Rainer Böger. Long-term intermittent exposure to high altitude elevates asymmetric dimethylarginine in first exposed young adults. High Alt Med Biol. 18:226-233, 2017.-Hypoxia-induced dysregulation of pulmonary and cerebral circulation may be related to an impaired nitric oxide (NO) pathway. We investigated the effect of chronic intermittent hypobaric hypoxia (CIH) on metabolites of the NO pathway. We measured asymmetric and symmetric dimethylarginine (ADMA and SDMA) and monomethyl-L-arginine (L-NMMA) and assessed their associations with acclimatization in male draftees (n = 72) undergoing CIH shifts at altitude (3550 m) during 3 months. Sixteen Andean natives living at altitude (3675 m) (chronic hypobaric hypoxia [CH]) were included for comparison. In CIH, ADMA and L-NMMA plasma concentrations increased from 1.14 ± 0.04 to 1.95 ± 0.09 μmol/L (mean ± SE) and from 0.22 ± 0.07 to 0.39 ± 0.03 μmol/L, respectively, (p < 0.001 for both) after 3 months, whereas SDMA did not change. The concentrations of ADMA and L-NMMA were higher in CH (3.48 ± 0.07, 0.53 ± 0.08 μmol/L; p < 0.001) as compared with CIH. In both CIH and CH, ADMA correlated with hematocrit (r 2  = 0.07, p < 0.05; r 2  = 0.26; p < 0.01). In CIH, an association of ADMA levels with poor acclimatization status was observed. We conclude that the endogenous NO synthase inhibitors, ADMA and L-NMMA, are elevated in hypoxia. This may contribute to impaired NO production at altitude and may also be predictive of altitude-associated health impairment.

  12. Angiotensin-converting enzyme genotype and arterial oxygen saturation at high altitude in Peruvian Quechua.

    Science.gov (United States)

    Bigham, Abigail W; Kiyamu, Melisa; León-Velarde, Fabiola; Parra, Esteban J; Rivera-Ch, Maria; Shriver, Mark D; Brutsaert, Tom D

    2008-01-01

    The I-allele of the angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism has been associated with performance benefits at high altitude (HA). In n = 142 young males and females of largely Quechua origins in Peru, we evaluated 3 specific hypotheses with regard to the HA benefits of the I-allele: (1) the I-allele is associated with higher arterial oxygen saturation (Sa(O(2))) at HA, (2) the I-allele effect depends on the acclimatization state of the subjects, and (3) the putative I-allele effect on Sa(O(2)) is mediated by the isocapnic hypoxic ventilatory response (HVR, l/min(1)/% Sa(O(2))(1)). The subject participants comprised two different study groups including BLA subjects (born at low altitude) who were lifelong sea-level residents transiently exposed to hypobaric hypoxia (<24 h) and BHA subjects (born at HA) who were lifelong residents of HA. To control for the possibility of population stratification, Native American ancestry proportion (NAAP) was estimated as a covariate for each individual using a panel of 70 ancestry-informative molecular markers (AIMS). At HA, resting and exercise Sa(O(2)) was strongly associated with the ACE genotype, p = 0.008 with approximately 4% of the total variance in Sa(O(2)) attributed to ACE genotype. Moreover, I/I individuals maintained approximately 2.3 percentage point higher Sa(O(2)) compared to I/D and D/D. This I-allele effect was evident in both BLA and BHA groups, suggesting that acclimatization state has little influence on the phenotypic expression of the ACE gene. Finally, ACE genotype was not associated with the isocapnic HVR, although HVR had a strong independent effect on Sa(O(2)) (p = 0.001). This suggests that the I-allele effect on Sa(O(2)) is not mediated by the peripheral control of breathing, but rather by some other central cardiopulmonary effect of the ACE gene on the renin-angiotensin-aldosterone system (RAAS).

  13. Essentials in the diagnosis of acid-base disorders and their high altitude application.

    Science.gov (United States)

    Paulev, P E; Zubieta-Calleja, G R

    2005-09-01

    This report describes the historical development in the clinical application of chemical variables for the interpretation of acid-base disturbances. The pH concept was already introduced in 1909. Following World War II, disagreements concerning the definition of acids and bases occurred, and since then two strategies have been competing. Danish scientists in 1923 defined an acid as a substance able to give off a proton at a given pH, and a base as a substance that could bind a proton, whereas the North American Singer-Hasting school in 1948 defined acids as strong non-buffer anions and bases as non-buffer cations. As a consequence of this last definition, electrolyte disturbances were mixed up with real acid-base disorders and the variable, strong ion difference (SID), was introduced as a measure of non-respiratory acid-base disturbances. However, the SID concept is only an empirical approximation. In contrast, the Astrup/Siggaard-Andersen school of scientists, using computer strategies and the Acid-base Chart, has made diagnosis of acid-base disorders possible at a glance on the Chart, when the data are considered in context with the clinical development. Siggaard-Andersen introduced Base Excess (BE) or Standard Base Excess (SBE) in the extracellular fluid volume (ECF), extended to include the red cell volume (eECF), as a measure of metabolic acid-base disturbances and recently replaced it by the term Concentration of Titratable Hydrogen Ion (ctH). These two concepts (SBE and ctH) represent the same concentration difference, but with opposite signs. Three charts modified from the Siggaard-Andersen Acid-Base Chart are presented for use at low, medium and high altitudes of 2500 m, 3500 m, and 4000 m, respectively. In this context, the authors suggest the use of Titratable Hydrogen Ion concentration Difference (THID) in the extended extracellular fluid volume, finding it efficient and better than any other determination of the metabolic component in acid

  14. The Quechua manta pouch: a caretaking practice for buffering the Peruvian infant against the multiple stressors of high altitude.

    Science.gov (United States)

    Tronick, E Z; Thomas, R B; Daltabuit, M

    1994-08-01

    The manta pouch--a caretaking practice of tightly swaddling and enclosing the infant in a set of cloths and blankets--and other caretaking practices are described for high-altitude resident (> 4,000 m) Quechua mother-infant pairs (N = 14). The manta pouch modifies the microenvironment inside the pouch so that, compared to the ambient environment, the temperature is higher and more stable, the humidity is higher, the partial pressure of O2 is lower, and stimulation levels are reduced. As the infant gets older, the characteristics of the pouch are modified such that the infant is increasingly exposed to ambient conditions. These caretaking practices may benefit the infant by buffering the infant from the multiple ecological stressors of high altitude, but they may also incur costs by exposing the infant to additional microenvironmental stressors (e.g., higher CO2 levels) and by reducing stimulation and limiting infant movement.

  15. Levels of protein hydroperoxides and carbonyl groups in guinea pigs native of high altitudes (Huancavelica, 3660 m)

    OpenAIRE

    Huayta, Roxana; Zúñiga, Haydée; Esquerre, Cynthia; Hernández, Luz; Carranza, Elizabeth

    2014-01-01

    The influence of hypobaric hypoxia on protein oxidation in lungs, heart, liver, kidneys and testicles of high altitude native guinea pigs (Huancavelica, 3660 m) in comparison to sea level (Lima, 150 m) native guinea pigs was evaluated. The concentration of protein hydroperoxides (POOH) and carbonyl groups (GC) as markers of protein oxidation, as well as total thiols (TT) concentration, powerful reducing agents that act as live antioxidants were determined. The results showed low concentration...

  16. The Use of Dexamethasone in Support of High-Altitude Ground Operations and Physical Performance: Review of the Literature

    Science.gov (United States)

    2014-12-01

    rates vary dramatically, the physiological effect of hypobaric high-altitude hypoxia (HHH) is ubiquitous.1,2 Symptoms of less severe cases of HHH...staff member on a quarterly basis at the UHM Fellowship Program and Multiplace Hyperbaric Chamber Wilford Hall San Anto- nio MHS, Texas. Initially...oc- cupational, and undersea hyperbaric medicine. Lt Col (Ret) Wright, PhD, CAsP, is a full-time faculty member at the USAF School of Aerospace

  17. Changes in labial capillary density on ascent to and descent from high altitude [version 1; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Edward Gilbert-Kawai

    2016-08-01

    Full Text Available Present knowledge of how the microcirculation is altered by prolonged exposure to hypoxia at high altitude is incomplete and modification of existing analytical techniques may improve our knowledge considerably. We set out to use a novel simplified method of measuring in vivo capillary density during an expedition to high altitude using a CytoCam incident dark field imaging video-microscope. The simplified method of data capture involved recording one-second images of the mucosal surface of the inner lip to reveal data about microvasculature density in ten individuals. This was done on ascent to, and descent from, high altitude. Analysis was conducted offline by two independent investigators blinded to the participant identity, testing conditions and the imaging site.  Additionally we monitored haemoglobin concentration and haematocrit data to see if we could support or refute mechanisms of altered density relating to vessel recruitment. Repeated sets of paired values were compared using Kruskall Wallis Analysis of Variance tests, whilst comparisons of values between sites was by related samples Wilcoxon Signed Rank Test. Correlation between different variables was performed using Spearman’s rank correlation coefficient, and concordance between analysing investigators using intra-class correlation coefficient. There was a significant increase in capillary density from London on ascent to high altitude; median capillaries per field of view area increased from 22.8 to 25.3 (p=0.021. There was a further increase in vessel density during the six weeks spent at altitude (25.3 to 32.5, p=0.017. Moreover, vessel density remained high on