WorldWideScience

Sample records for high axial resolution

  1. High-resolution axial MR imaging of tibial stress injuries

    Directory of Open Access Journals (Sweden)

    Mammoto Takeo

    2012-05-01

    Full Text Available Abstract Purpose To evaluate the relative involvement of tibial stress injuries using high-resolution axial MR imaging and the correlation with MR and radiographic images. Methods A total of 33 patients with exercise-induced tibial pain were evaluated. All patients underwent radiograph and high-resolution axial MR imaging. Radiographs were taken at initial presentation and 4 weeks later. High-resolution MR axial images were obtained using a microscopy surface coil with 60 × 60 mm field of view on a 1.5T MR unit. All images were evaluated for abnormal signals of the periosteum, cortex and bone marrow. Results Nineteen patients showed no periosteal reaction at initial and follow-up radiographs. MR imaging showed abnormal signals in the periosteal tissue and partially abnormal signals in the bone marrow. In 7 patients, periosteal reaction was not seen at initial radiograph, but was detected at follow-up radiograph. MR imaging showed abnormal signals in the periosteal tissue and entire bone marrow. Abnormal signals in the cortex were found in 6 patients. The remaining 7 showed periosteal reactions at initial radiograph. MR imaging showed abnormal signals in the periosteal tissue in 6 patients. Abnormal signals were seen in the partial and entire bone marrow in 4 and 3 patients, respectively. Conclusions Bone marrow abnormalities in high-resolution axial MR imaging were related to periosteal reactions at follow-up radiograph. Bone marrow abnormalities might predict later periosteal reactions, suggesting shin splints or stress fractures. High-resolution axial MR imaging is useful in early discrimination of tibial stress injuries.

  2. Improving axial resolution in confocal microscopy with new high refractive index mounting media.

    Directory of Open Access Journals (Sweden)

    Coralie Fouquet

    Full Text Available Resolution, high signal intensity and elevated signal to noise ratio (SNR are key issues for biologists who aim at studying the localisation of biological structures at the cellular and subcellular levels using confocal microscopy. The resolution required to separate sub-cellular biological structures is often near to the resolving power of the microscope. When optimally used, confocal microscopes may reach resolutions of 180 nm laterally and 500 nm axially, however, axial resolution in depth is often impaired by spherical aberration that may occur due to refractive index mismatches. Spherical aberration results in broadening of the point-spread function (PSF, a decrease in peak signal intensity when imaging in depth and a focal shift that leads to the distortion of the image along the z-axis and thus in a scaling error. In this study, we use the novel mounting medium CFM3 (Citifluor Ltd., UK with a refractive index of 1.518 to minimize the effects of spherical aberration. This mounting medium is compatible with most common fluorochromes and fluorescent proteins. We compare its performance with established mounting media, harbouring refractive indices below 1.500, by estimating lateral and axial resolution with sub-resolution fluorescent beads. We show furthermore that the use of the high refractive index media renders the tissue transparent and improves considerably the axial resolution and imaging depth in immuno-labelled or fluorescent protein labelled fixed mouse brain tissue. We thus propose to use those novel high refractive index mounting media, whenever optimal axial resolution is required.

  3. The AX-PET project Demonstration of a high resolution axial 3D PET

    CERN Document Server

    Bolle, E; Casella, C; Chesi, E; Clinthorne, N; Cochran, E; De Leo, R; Dissertori, G; Djambazov, G; Fanti, V; Honscheid, K; Huh, S; Johnson, I; Joram, C; Kagan, H; Lustermann, W; Meddi, F; Nappi, E; Nessi-Tedaldi, F; Oliver, J F; Pauss, P; Rafecas, M; Renker, D; Rudge, A; Schinzel, D; Schneider, T; Seguinot, J; Smith, S; Solevi, P; Stapnes, S; Weilhammer, P

    2010-01-01

    The AX-PET is a new geometrical concept for a high resolution 3D PET scanner, based on matrices of axially oriented LYSO crystals interleaved by stacks of WLS, both individually read out by G-APDs. A PET demonstrator, based on two detector modules used in coincidence, is currently under construction.

  4. A high resolution TOF-PET concept with axial geometry and digital SiPM readout

    CERN Document Server

    Casella, C; Joram, C; Schneider, T

    2014-01-01

    The axial arrangement of long scintillation crystals is a promising concept in PET instrumentation to address the need for optimized resolution and sensitivity. Individual crystal readout and arrays of wavelength shifter strips placed orthogonally to the crystals lead to a 3D-detection of the annihilations photons. A fully operational demonstrator scanner, developed by the AX-PET collaboration, proved the potential of this concept in terms of energy and spatial resolution as well as sensitivity. This paper describes a feasibility study, performed on axial prototype detector modules with 100 mm long LYSO crystals, read out by the novel digital Silicon Photomultipliers (dSiPM) from Philips. With their highly integrated readout electronics and excellent intrinsic time resolution, dSiPMs allow for compact, axial detector modules which may extend the potential of the axial PET concept by time of fl ight capabilities (TOF-PET). A coincidence time resolution of 211 ps (FWHM) was achieved in the coincidence of two ax...

  5. High-resolution AUV mapping and lava flow ages at Axial Seamount

    Science.gov (United States)

    Clague, D. A.; Paduan, J. B.; Dreyer, B. M.; Caress, D. W.; Martin, J.

    2011-12-01

    Mapping along mid-ocean ridges, as on land, requires identification of flow boundaries and sequence, and ages of some flows to understand eruption history. Multibeam sonars on autonomous underwater vehicles (AUV) now generate 1-m resolution maps that resolve lava pillars, internal flow structures and boundaries, and lava flow emplacement sequences using crosscutting relations and abundance of fissures. MBARI has now mapped the summit caldera floor and rims and the upper south rift zone on Axial Seamount on the Juan de Fuca Ridge. With the advent of the high-resolution bathymetry and the ability to observe flow contacts to determine superposition using ROVs and submersibles, the missing component has been determining absolute ages of the flows. We used the MBARI ROV Doc Ricketts to collect short push cores (<30 cm) of the thin sediment nestled between pillow lava lobes and sieve and then hand-pick planktic foraminifera from the base of the cores to date by AMS 14C. Ages of planktic foraminifera are marine-calibrated in years before present, and provide minimum ages for the underlying flows, as there is probably some basal sediment that is not recovered. 14C ages have been determined for 10 cores near the summit of Axial Seamount and for 6 from the lowermost south rift. Ages of nearby samples commonly yield statistically identical ages, and 2 cores near the center of the caldera had multiple layers dated. These ages systematically increase with depth, indicating that redistribution of sediment by bottom currents does not significantly affect the stratigraphy. We will expand these collections in summer 2011. The coring is accompanied by collection of flow samples for chemistry and video observations to confirm contact locations and flow superposition inferred from the mapping data. Six ages from the lowermost part of the south rift of Axial Seamount include samples on a cone with deep summit crater that is ~16,580 aBP and on 5 flows between 950 and 1510 aBP. Two

  6. High-resolution AUV mapping of the 2015 flows at Axial Seamount, Juan de Fuca Ridge

    Science.gov (United States)

    Paduan, J. B.; Chadwick, W. W., Jr.; Clague, D. A.; Le Saout, M.; Caress, D. W.; Thomas, H. J.; Yoerger, D.

    2016-12-01

    Lava flows erupted in April 2015 at Axial Seamount were mapped at 1-m resolution with the AUV Sentry in August 2015 and the MBARI Mapping AUVs in July 2016 and observed and sampled with ROVs on those same expeditions. Thirty percent of terrain covered by new flows had been mapped by the MBARI AUVs prior to the eruption. Differencing of before and after maps (using ship-collected bathymetry where the AUV had not mapped before) allows calculation of extents and volumes of flows and shows new fissures. The maps reveal unexpected fissure patterns and shifts in the style of flow emplacement through a single eruption. There were 11 separate flows totaling 1.48 x 108 m3 of lava erupted from numerous en echelon fissures over 19 km on the NE caldera floor, on the NE flank, and down the N rift zone. Flows in and around the caldera have maximum thicknesses of 5-19 m. Most erupted as sheet flows and spread along intricate channels that terminated in thin margins. Some utilized pre-existing fissures. Some flows erupted from short fissures, while at least two longer new fissures produced little or no lava. A flow on the upper N rift has a spectacular lava channel flanked by narrow lava pillars supporting a thin roof left after the flow drained. A shatter ring still emanating warm fluid is visible in the map as a 15-m wide low cone. Hundreds of exploded pillows were observed but are not discernable in the bathymetry. The northern-most three flows deep on the N rift are similar in area to the others but comprise the bulk of the eruption volume. Differencing of ship-based bathymetry shows only these flows. Near the eruptive fissures they are sheet flows, but as they flowed downslope they built complexes of coalesced pillow mounds up to 67-128 m thick. Changes in flow morphology occurred through the course of the eruption. Large pillow mounds had molten cores that deformed as the eruption progressed. One flow began as a thin, effusive sheet flow but as the eruption rate decreased, a

  7. Axial Super-resolution Evanescent Wave Tomography

    CERN Document Server

    Pendharker, Sarang; Newman, Ward; Ogg, Stephen; Nazemifard, Neda; Jacob, Zubin

    2016-01-01

    Optical tomographic reconstruction of a 3D nanoscale specimen is hindered by the axial diffraction limit, which is 2-3 times worse than the focal plane resolution. We propose and experimentally demonstrate an axial super-resolution evanescent wave tomography (AxSET) method that enables the use of regular evanescent wave microscopes like Total Internal Reflection Fluorescence Microscope (TIRF) beyond surface imaging, and achieve tomographic reconstruction with axial super-resolution. Our proposed method based on Fourier reconstruction achieves axial super-resolution by extracting information from multiple sets of three-dimensional fluorescence images when the sample is illuminated by an evanescent wave. We propose a procedure to extract super-resolution features from the incremental penetration of an evanescent wave and support our theory by 1D (along the optical axis) and 3D simulations. We validate our claims by experimentally demonstrating tomographic reconstruction of microtubules in HeLa cells with an axi...

  8. Echo-planar magnetic resonance imaging (EPI) with high-resolution matrix in intra-axial brain tumors

    Energy Technology Data Exchange (ETDEWEB)

    Bruening, R.; Scheidler, J.; Porn, U.; Reiser, M. [Institute of Diagnostic Radiology, Klinikum Grosshadern, University of Munich (Germany); Seelos, K.; Yousry, T. [Department of Neuroradiology, Institute of Diagnostic Radiology, Klinikum Grosshadern, University of Munich (Germany); Exner, H. [Institute for Medical Epidemiology, Klinikum Grosshadern, University of Munich, Munich (Germany); Rosen, B.R. [Department of Radiology, Massachusetts General Hospital, NMR Center, Charlestown, MA (United States)

    1999-09-01

    The aim of this study was to assess the potential of high-speed interleaved echo-planar imaging (EPI) to achieve diagnostic image quality comparable to T2-weighted imaging in patients with brain tumors. Seventeen patients with intra-axial, supratentorial tumors (10 untreated gliomas, 7 radiated gliomas) were investigated on a 1.5-T scanner. The conventional scan (SE, TR/TE = 2200/80 ms, 18 slices) was acquired in 8 min, 4 s, and EPI (TR/TE = 3000/80 ms, 18 slices) was completed in 25 s. The films were compared in a blinded trail by three radiologists. On the general impression and anatomic display, both sequences were rated to be of similar quality. Artifacts were slightly more pronounced at the skull base and around surgical clips using EPI. Tumor delineation was nearly equivalent using EPI, compared with the T2-weighted sequence. Echo-planar imaging reached diagnostic quality in all patients. Interleaved high-resolution EPI yielded sufficient quality to depict intra-axial, supratentorial brain tumors. Since EPI can be obtained in a small fraction of the time needed for conventional spin echo, in addition to other indications it could be considered to study patients unable to cooperate. (orig.) With 3 figs., 3 tabs., 27 refs.

  9. Burn-Up Determination by High Resolution Gamma Spectrometry: Axial and Diametral Scanning Experiments

    Energy Technology Data Exchange (ETDEWEB)

    Forsyth, R.S.; Blackadder, W.H.; Ronqvist, N.

    1967-02-15

    In the gamma spectrometric determination of burn-up the use of a single fission product as a monitor of the specimen fission rate is subject to errors caused by activity saturation or, in certain cases, fission product migration. Results are presented of experiments in which all the resolvable gamma peaks in the fission product spectrum have been used to calculate the fission rate; these results form a pattern which reflect errors in the literature values of the gamma branching ratios, fission yields etc., and also represent a series of empirical correction factors. Axial and diametral scanning experiments on a long-irradiated low-enrichment fuel element are also described and demonstrate that it is possible to differentiate between fissions in U-235 and in Pu-239 respectively by means of the ratios of the Ru-106 activity to the activities of the other fission products.

  10. Axial super-resolution evanescent wave tomography.

    Science.gov (United States)

    Pendharker, Sarang; Shende, Swapnali; Newman, Ward; Ogg, Stephen; Nazemifard, Neda; Jacob, Zubin

    2016-12-01

    Optical tomographic reconstruction of a three-dimensional (3D) nanoscale specimen is hindered by the axial diffraction limit, which is 2-3 times worse than the focal plane resolution. We propose and experimentally demonstrate an axial super-resolution evanescent wave tomography method that enables the use of regular evanescent wave microscopes like the total internal reflection fluorescence microscope beyond surface imaging and achieve a tomographic reconstruction with axial super-resolution. Our proposed method based on Fourier reconstruction achieves axial super-resolution by extracting information from multiple sets of 3D fluorescence images when the sample is illuminated by an evanescent wave. We propose a procedure to extract super-resolution features from the incremental penetration of an evanescent wave and support our theory by one-dimensional (along the optical axis) and 3D simulations. We validate our claims by experimentally demonstrating tomographic reconstruction of microtubules in HeLa cells with an axial resolution of ∼130  nm. Our method does not require any additional optical components or sample preparation. The proposed method can be combined with focal plane super-resolution techniques like stochastic optical reconstruction microscopy and can also be adapted for THz and microwave near-field tomography.

  11. Axial super-resolution evanescent wave tomography

    Science.gov (United States)

    Pendharker, Sarang; Shende, Swapnali; Newman, Ward; Ogg, Stephen; Nazemifard, Neda; Jacob, Zubin

    2016-12-01

    Optical tomographic reconstruction of a 3D nanoscale specimen is hindered by the axial diffraction limit, which is 2-3 times worse than the focal plane resolution. We propose and experimentally demonstrate an axial super-resolution evanescent wave tomography (AxSET) method that enables the use of regular evanescent wave microscopes like Total Internal Reflection Fluorescence Microscope (TIRF) beyond surface imaging, and achieve tomographic reconstruction with axial super-resolution. Our proposed method based on Fourier reconstruction achieves axial super-resolution by extracting information from multiple sets of three-dimensional fluorescence images when the sample is illuminated by an evanescent wave. We propose a procedure to extract super-resolution features from the incremental penetration of an evanescent wave and support our theory by 1D (along the optical axis) and 3D simulations. We validate our claims by experimentally demonstrating tomographic reconstruction of microtubules in HeLa cells with an axial resolution of $\\sim$130 nm. Our method does not require any additional optical components or sample preparation. The proposed method can be combined with focal plane super-resolution techniques like STORM and can also be adapted for THz and microwave near-field tomography.

  12. Enhancement of Optical Coherence Tomography Axial Resolution by Spectral Shaping

    Institute of Scientific and Technical Information of China (English)

    孙汕; 郭继华; 高湔松; 薛平

    2002-01-01

    We propose a new method of changing the spectrum shape to improve the axial resolution of optical coherencetomography (OCT). Theoretical analysis shows that certain spectral shaping can shorten the coherence length.Comparisons of the simulation and experimental measurements of spectral shape and axial resolution of OCTare given, showing that the axial resolution of OCT is enhanced by a factor of 1.4.

  13. Study of $ \\bar{p} $ and $ \\bar{n} $ annihilations at LEAR with OBELIX, a large acceptance and high resolution detector based on the Open Axial Field Spectrometer

    CERN Multimedia

    2002-01-01

    % PS201 Study of $\\bar{p}$ and $\\bar{n}$ annihilations at LEAR with OBELIX, a large acceptance and high resolution detector based on the Open Axial Field Spectrometer \\\\ \\\\OBELIX is designed to study exclusive final states of antiproton and antineutron annihilations at low energies with protons and nuclei. \\\\ \\\\The physics motivations of the experiment are:\\\\ \\\\\\begin{itemize} \\item (gg, ggg), hybrids ($ q \\bar{q} g $), multiquarks ($ q q \\bar{q} \\bar{q} $) and light mesons ($ q \\bar{q} $) produced in $ N \\bar{N} $ annihilations and study of their spectroscopy and decays. Also broad structures will be searched for by comparing identical decay modes in exclusive final states of the same type occuring from initial states with different angular momentum or isospin. \\item Study of the dynamics of $ N \\bar{N} $ interactions and of the dependence of the final and intermediate resonant states of annihilation upon the quantum numbers of the initial $ N \\bar{N} $ state (angular momentum: S and P-wave in $\\bar{p}p $ at...

  14. 3D micro-particle image modeling and its application in measurement resolution investigation for visual sensing based axial localization in an optical microscope

    Science.gov (United States)

    Wang, Yuliang; Li, Xiaolai; Bi, Shusheng; Zhu, Xiaofeng; Liu, Jinhua

    2017-01-01

    Visual sensing based three dimensional (3D) particle localization in an optical microscope is important for both fundamental studies and practical applications. Compared with the lateral (X and Y) localization, it is more challenging to achieve a high resolution measurement of axial particle location. In this study, we aim to investigate the effect of different factors on axial measurement resolution through an analytical approach. Analytical models were developed to simulate 3D particle imaging in an optical microscope. A radius vector projection method was applied to convert the simulated particle images into radius vectors. With the obtained radius vectors, a term of axial changing rate was proposed to evaluate the measurement resolution of axial particle localization. Experiments were also conducted for comparison with that obtained through simulation. Moreover, with the proposed method, the effects of particle size on measurement resolution were discussed. The results show that the method provides an efficient approach to investigate the resolution of axial particle localization.

  15. Spectral estimation optical coherence tomography for axial super-resolution (Conference Presentation)

    Science.gov (United States)

    Liu, Xinyu; Yu, Xiaojun; Wang, Nanshuo; Bo, En; Luo, Yuemei; Chen, Si; Cui, Dongyao; Liu, Linbo

    2016-03-01

    The sample depth reflectivity profile of Fourier domain optical coherence tomography (FD-OCT) is estimated from the inverse Fourier transform of the spectral interference signals (interferograms). As a result, the axial resolution is fundamentally limited by the coherence length of the light source. We demonstrate an axial resolution improvement method by using the autoregressive spectral estimation technique to instead of the inverse Fourier transform to analyze the spectral interferograms, which is named as spectral estimation OCT (SE-OCT). SE-OCT improves the axial resolution by a factor of up to 4.7 compared with the corresponding FD-OCT. Furthermore, SE-OCT provides a complete sidelobe suppression in the point-spread function. Using phantoms such as an air wedge and micro particles, we prove the ability of resolution improvement. To test SE-OCT for real biological tissue, we image the rat cornea and demonstrate that SE-OCT enables clear identification of corneal endothelium anatomical details ex vivo. We also find that the performance of SE-OCT is depended on SNR of the feature object. To evaluate the potential usage and define the application scope of SE-OCT, we further investigate the property of SNR dependence and the artifacts that may be caused. We find SE-OCT may be uniquely suited for viewing high SNR layer structures, such as the epithelium and endothelium in cornea, retina and aorta. Given that SE-OCT can be implemented in the FD-OCT devices easily, the new capabilities provided by SE-OCT are likely to offer immediate improvements to the diagnosis and management of diseases based on OCT imaging.

  16. Enhanced Axial Resolution of Wide-Field Two-Photon Excitation Microscopy by Line Scanning Using a Digital Micromirror Device

    Directory of Open Access Journals (Sweden)

    Jong Kang Park

    2017-03-01

    Full Text Available Temporal focusing multiphoton microscopy is a technique for performing highly parallelized multiphoton microscopy while still maintaining depth discrimination. While the conventional wide-field configuration for temporal focusing suffers from sub-optimal axial resolution, line scanning temporal focusing, implemented here using a digital micromirror device (DMD, can provide substantial improvement. The DMD-based line scanning temporal focusing technique dynamically trades off the degree of parallelization, and hence imaging speed, for axial resolution, allowing performance parameters to be adapted to the experimental requirements. We demonstrate this new instrument in calibration specimens and in biological specimens, including a mouse kidney slice.

  17. High-Frequency Axial Fatigue Test Procedures for Spectrum Loading

    Science.gov (United States)

    2016-07-20

    REPORT NO: NAWCADPAX/TIM-2016/49 HIGH - FREQUENCY AXIAL FATIGUE TEST PROCEEDURES FOR SPECTRUM LOADING by David T. Rusk, AIR...OF THE NAVY NAVAL AIR WARFARE CENTER AIRCRAFT DIVISION PATUXENT RIVER, MARYLAND NAWCADPAX/TIM-2016/49 20 July 2016 HIGH - FREQUENCY AXIAL...Technical Information Memorandum 3. DATES COVERED 4. TITLE AND SUBTITLE High - Frequency Axial Fatigue Test Procedures for Spectrum Loading

  18. High Resolution Elevation Contours

    Data.gov (United States)

    Minnesota Department of Natural Resources — This dataset contains contours generated from high resolution data sources such as LiDAR. Generally speaking this data is 2 foot or less contour interval.

  19. Axial resolution and the value of interpolating scan in multislice positron computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Senda, M.; Yonekura, Y.; Tamaki, N.; Tanaka, Y.; Komori, M.; Minato, K.; Torizuka, K.

    1985-05-01

    The authors have calculated the aperture function of a positron computed tomograph (PCT) with computer simulation and evaluated both theoretically and experimentally the axial resolution of a multislice PCT, Positologica III, which has 7 slices at the interval of 16mm. The axial point spread function (PSF) was approximately a triangle at or near the center of the field and the sensitivity for the slice decreased significantly as the source moved away off the image plane. Accordingly there are low sensitivity areas between an in-plane and the adjacent cross-plane. In experiments using a myocardial phantom, a small myocardial defect of 1cm diameter could not be detected when dropped into the gap between slices, although the machine had sufficiently high resolution to deliniate it if it was on the image plane. When long-axis images of the ''myocardium'' were reconstructed three-dimensionally from the images obtained in single object position, the ''inferior wall'' dropped into the gap and disappeared. In clinical myocardial scan with N-13 labeled ammonia in a normal volunteer, a false positive defect appeared in the inferior wall. However, when the object is slided half the slice interval to perform the ''interpolating'' scan and the two sets of images were interlaced with each other, no artifacts appeared. These results have suggested that the invisible regions between slices may be clinically significant if the object is thin enough in z-axis. In order to fill up the gaps between slices, it is valuable to perform the interpolating scan.

  20. Improving the axial and lateral resolution of three-dimensional fluorescence microscopy using random speckle illuminations.

    Science.gov (United States)

    Negash, Awoke; Labouesse, Simon; Sandeau, Nicolas; Allain, Marc; Giovannini, Hugues; Idier, Jérôme; Heintzmann, Rainer; Chaumet, Patrick C; Belkebir, Kamal; Sentenac, Anne

    2016-06-01

    We consider a fluorescence microscope in which several three-dimensional images of a sample are recorded for different speckle illuminations. We show, on synthetic data, that by summing the positive deconvolution of each speckle image, one obtains a sample reconstruction with axial and transverse resolutions that compare favorably to that of an ideal confocal microscope.

  1. Ultra high resolution tomography

    Energy Technology Data Exchange (ETDEWEB)

    Haddad, W.S.

    1994-11-15

    Recent work and results on ultra high resolution three dimensional imaging with soft x-rays will be presented. This work is aimed at determining microscopic three dimensional structure of biological and material specimens. Three dimensional reconstructed images of a microscopic test object will be presented; the reconstruction has a resolution on the order of 1000 A in all three dimensions. Preliminary work with biological samples will also be shown, and the experimental and numerical methods used will be discussed.

  2. High-resolution intravital microscopy.

    Directory of Open Access Journals (Sweden)

    Volker Andresen

    Full Text Available Cellular communication constitutes a fundamental mechanism of life, for instance by permitting transfer of information through synapses in the nervous system and by leading to activation of cells during the course of immune responses. Monitoring cell-cell interactions within living adult organisms is crucial in order to draw conclusions on their behavior with respect to the fate of cells, tissues and organs. Until now, there is no technology available that enables dynamic imaging deep within the tissue of living adult organisms at sub-cellular resolution, i.e. detection at the level of few protein molecules. Here we present a novel approach called multi-beam striped-illumination which applies for the first time the principle and advantages of structured-illumination, spatial modulation of the excitation pattern, to laser-scanning-microscopy. We use this approach in two-photon-microscopy--the most adequate optical deep-tissue imaging-technique. As compared to standard two-photon-microscopy, it achieves significant contrast enhancement and up to 3-fold improved axial resolution (optical sectioning while photobleaching, photodamage and acquisition speed are similar. Its imaging depth is comparable to multifocal two-photon-microscopy and only slightly less than in standard single-beam two-photon-microscopy. Precisely, our studies within mouse lymph nodes demonstrated 216% improved axial and 23% improved lateral resolutions at a depth of 80 µm below the surface. Thus, we are for the first time able to visualize the dynamic interactions between B cells and immune complex deposits on follicular dendritic cells within germinal centers (GCs of live mice. These interactions play a decisive role in the process of clonal selection, leading to affinity maturation of the humoral immune response. This novel high-resolution intravital microscopy method has a huge potential for numerous applications in neurosciences, immunology, cancer research and

  3. Improvement of Axial Resolution in Confocal Microscopy by an Optical Pupil Filter with Two Zones Phase-Shifted by π

    Institute of Scientific and Technical Information of China (English)

    林列; 王湘晖; 王肇圻; 母国光

    2003-01-01

    A filter with two zones phase-shifted by π is proposed to improve the axial resolution of confocal microscopes with a finite-sized detector. The optimum axial resolution for a given size of the detector can be achieved by adjusting the zone boundary of the filter. The experimental results are well in agreement with the theoretical predictions.

  4. Stall inception in a high-speed axial compressor

    Science.gov (United States)

    Cameron, Joshua David

    A research program designed to provide understanding of the fluid dynamic mechanisms that lead to rotating stall in the Notre Dame Stage 01 high-speed axial compressor is described. The stalling behavior of this compressor was studied with unsteady casing pressure measurements from a circumferentially spaced array of sensors. In addition, over rotor casing surface streak measurements were performed to investigate the time-averaged end-wall flow near the rotor at operating points near stall. Several investigative tools were applied to the analysis and interpretation of the unsteady casing pressure data. Traditional methods such as visual inspection, spatial Fourier decomposition, traveling wave energy and wavelet analysis were shown to be insufficient to characterize the pre-stall and stall inception behavior of the compressor. A new technique based on a windowed two-point correlation between adjacent sensors was developed and demonstrated to provide spatial and temporal resolution of both pre-stall and stall inception behavior. The spatial correlation technique was then applied to the analysis of stall inception data from experiments with asymmetric tip clearance. The non-uniform tip clearance was produced using the magnetic bearings which levitate the rotor shaft of the Notre Dame Transonic Axial Compressor facility. Both steady rotor centerline offset and rotor whirl were investigated. The results of these experiments, along with the surface streak measurements, provide evidence in support of recent computational observations (found in the literature) that predict that short length scale stall inception is related to specific features of the rotor tip clearance flow.

  5. High-resolution headlamp

    Science.gov (United States)

    Gut, Carsten; Cristea, Iulia; Neumann, Cornelius

    2016-04-01

    The following article shall describe how human vision by night can be influenced. At first, front lighting systems that are already available on the market will be described, followed by their analysis with respect to the positive effects on traffic safety. Furthermore, how traffic safety by night can be increased since the introduction of high resolution headlamps shall be discussed.

  6. Recent Results on High-Pressure Axial Blowers

    Science.gov (United States)

    Eckert, B.

    1947-01-01

    Considerable progress has, in recent times, been attained in the development of the high-pressure axial blower by well-planned research. The efforts are directed toward improving the efficiencies, which are already high for the axial blower, and in particular the delivery pressure heads. For high pressures multistage arrangements are used. Of fundamental importance is the careful design of all structural parts of the blower that are subject to the effects of the flow. In the present report, several recent results and experiences are reported, which are based on results of German engine research.

  7. Analysis of axial spatial resolution in a variable resolution x-ray cone beam CT (VRX-CBCT) system

    Science.gov (United States)

    Dahi, Bahram; Keyes, Gary S.; Rendon, David A.; DiBianca, Frank A.

    2008-03-01

    The Variable Resolution X-ray (VRX) technique has been successfully used in a Cone-Beam CT (CBCT) system to increase the spatial resolution of CT images in the transverse plane. This was achieved by tilting the Flat Panel Detector (FPD) to smaller vrx y angles in a VRX Cone Beam CT (VRX-CBCT) system. In this paper, the effect on the axial spatial resolution of CT images created by the VRX-CBCT system is examined at different vrx x angles, where vrx x is the tilting angle of the FPD about its x-axis. An amorphous silicon FPD with a CsI scintillator is coupled with a micro-focus x-ray tube to form a CBCT. The FPD is installed on a rotating frame that allows rotation of up to 90° about x and y axes of the FPD. There is no rotation about the z-axis (i.e. normal to the imaging surface). Tilting the FPD about its x-axis (i.e. decreasing the vrx x angle) reduces both the width of the line-spread function and the sampling distance by a factor of sin vrx x, thereby increasing the theoretical detector pre-sampling spatial resolution proportionately. This results in thinner CT slices that in turn help increase the axial spatial resolution of the CT images. An in-house phantom is used to measure the MTF of the reconstructed CT images at different vrx x angles.

  8. High Resolution Acoustical Imaging

    Science.gov (United States)

    1989-05-01

    1028 (September 1982). 26 G. Arfken , Mathematical Methods for Physicists (Academic Press, New York, 1971), 2nd printing, pp.662-666. 27 W. R. Hahn...difference in the approach used by the two methods , as noted in the previous paragraph, forming a direct mathematical com- parison may be impossible...examines high resolution methods which use a linear array to locate stationary objects which have scattered the fressure waves. Several;- new methods

  9. High resolution differential thermometer

    Directory of Open Access Journals (Sweden)

    Gotra Z. Yu.

    2009-11-01

    Full Text Available Main schematic solutions of differential thermometers with measurement resolution about 0.001°C are considered. Differential temperature primary transducer realized on a transistor differential circuit in microampere mode. Analytic calculation and schematic mathematic simulation of primary transducer are fulfilled. Signal transducer is realized on a high precision Zero-Drift Single-Supply Rail-to-Rail operation amplifier AD8552 and 24-Bit S-D microconverter ADuC834.

  10. High Power Co-Axial Coupler

    Energy Technology Data Exchange (ETDEWEB)

    Neubauer, M. [Muons, Inc.; Dudas, A. [Muons, Inc.; Rimmer, Robert A. [JLAB; Guo, Jiquan [JLAB; Williams, R. Scott [JLAB

    2013-12-01

    A very high power Coax RF Coupler (MW-Level) is very desirable for a number of accelerator and commercial applications. For example, the development of such a coupler operating at 1.5 GHz may permit the construction of a higher-luminosity version of the Electron-Ion Collider (EIC) being planned at JLab. Muons, Inc. is currently funded by a DOE STTR grant to develop a 1.5-GHz high-power doublewindowcoax coupler with JLab (about 150 kW). Excellent progress has been made on this R&D project, so we propose an extension of this development to build a very high power coax coupler (MW level peak power and a max duty factor of about 4%). The dimensions of the current coax coupler will be scaled up to provide higher power capability.

  11. The axial topographic high at intermediate and fast spreading ridges

    Science.gov (United States)

    Carbotte, Suzanne M.; MacDonald, Ken C.

    1994-12-01

    An axial topographic high is commonly observed at both fast spreading ridges and some segments of intermediate spreading ridges. At fast rates the axial high is primarily created by the buoyancy of hot rock and magma beneath the rise. As newly formed crust is transported off axis, little vestige of an axial high is observed on the ridge flanks. In contrast, at intermediate rates, a significant component of the positive topography may be a volcanic construction, preserved on the ridge flanks as abyssal hills, which are slit axial volcanoes. We suggest this difference in the nature of the axial high reflects a lithosphere strong enough to support construction of a volcanic crestal ridge at intermediate spreading rates, but only rarely at fast rates. Relict overlap ridges, found within the discordant zones left by overlapping spreading centers, is one class of ridge-flank topography which appears to have a significant volcanic constructional component even at fast spreading ridges. Unlike topography away from these discontinuities, the relief and shape of overlapping spreading centers is preserved as relict ridge tips are rafted onto the ridge flanks. Reduced magma supply at these discontinuities may give rise to an axial lithosphere strong enough to support volcanic construction of overlap ridges. Low axial lithospheric strength may also account for the lack of normal faults within the innermost 1-2 km of fast, and some intermediate, spreading ridges. With a thin/weak brittle layer at the ridge crest, tensile failure will predominate and few normal faults will form. Depths to the axial magma chamber reflector observed in multi-channel seismic data limit the thickness of the brittel layer on axis to less than 1-2 km for much of the East Pacific Rise (EPR). This depth is comparable to depths over which tensile failure within the oceanic crust will predominate, estimated from the Griffith criteria for fracture initiation (approx. 0.5-1.5 km). As the brittle layer

  12. Saturn's rings - high resolution

    Science.gov (United States)

    1981-01-01

    Voyager 2 obtained this high-resolution picture of Saturn's rings Aug. 22, when the spacecraft was 4 million kilometers (2.5 million miles) away. Evident here are the numerous 'spoke' features, in the B-ring; their very sharp, narrow appearance suggests short formation times. Scientists think electromagnetic forces are responsible in some way for these features, but no detailed theory has been worked out. Pictures such as this and analyses of Voyager 2's spoke movies may reveal more clues about the origins of these complex structures. The Voyager project is managed for NASA by the Jet Propulsion Laboratory, Pasadena, Calif.

  13. High Resolution Laboratory Spectroscopy

    CERN Document Server

    Brünken, Sandra

    2016-01-01

    In this short review we will highlight some of the recent advancements in the field of high-resolution laboratory spectroscopy that meet the needs dictated by the advent of highly sensitive and broadband telescopes like ALMA and SOFIA. Among these is the development of broadband techniques for the study of complex organic molecules, like fast scanning conventional absorption spectroscopy based on multiplier chains, chirped pulse instrumentation, or the use of synchrotron facilities. Of similar importance is the extension of the accessible frequency range to THz frequencies, where many light hydrides have their ground state rotational transitions. Another key experimental challenge is the production of sufficiently high number densities of refractory and transient species in the laboratory, where discharges have proven to be efficient sources that can also be coupled to molecular jets. For ionic molecular species sensitive action spectroscopic schemes have recently been developed to overcome some of the limita...

  14. High Time Resolution Astrophysics

    CERN Document Server

    Phelan, Don; Shearer, Andrew

    2008-01-01

    High Time Resolution Astrophysics (HTRA) is an important new window to the universe and a vital tool in understanding a range of phenomena from diverse objects and radiative processes. This importance is demonstrated in this volume with the description of a number of topics in astrophysics, including quantum optics, cataclysmic variables, pulsars, X-ray binaries and stellar pulsations to name a few. Underlining this science foundation, technological developments in both instrumentation and detectors are described. These instruments and detectors combined cover a wide range of timescales and can measure fluxes, spectra and polarisation. These advances make it possible for HTRA to make a big contribution to our understanding of the Universe in the next decade.

  15. 2.2 microm axial resolution optical coherence tomography based on a 400 nm-bandwidth superluminescent diode.

    Science.gov (United States)

    Chan, Ming-Che; Su, Yi-Shin; Lin, Ching-Fuh; Sun, Chi-Kuang

    2006-01-01

    We demonstrate 2.2 microm axial resolution optical coherence tomography (OCT) in 1.1-1.7 microm wavelength regime by using a nonidentical multiple-quantum-well (MQW) superluminescent diode (SLD) with record-bandwidth emission. The compact, low-cost, and reliable light source with extreme broadband emission demonstrates significant potentials for spectroscopic and commercial OCT applications requiring ultrahigh spatial resolution.

  16. High Resolution Formaldehyde Photochemistry

    Science.gov (United States)

    Ernest, C. T.; Bauer, D.; Hynes, A. J.

    2010-12-01

    Formaldehyde (HCHO) is the most abundant and most important organic carbonyl compound in the atmosphere. The sources of formaldehyde are the oxidation of methane, isoprene, acetone, and other volatile organic compounds (VOCs); fossil fuel combustion; and biomass burning. The dominant loss mechanism for formaldehyde is photolysis which occurs via two pathways: (R1) HCHO + hv → HCO + H (R2) HCHO + hv → H2 + CO The first pathway (R1) is referred to as the radical channel, while the second pathway (R2) is referred to as the molecular channel. The products of both pathways play a significant role in atmospheric chemistry. The CO that is produced in the molecular channel undergoes further oxidation to produce CO2. Under atmospheric conditions, the H atom and formyl radical that are produced in the radical channel undergo rapid reactions with O2 to produce the hydroperoxyl radical (HO2) via (R3) and (R4). (R3) HCO + O2 → HO2 + CO (R4) H + O2 → HO2 Thus, for every photon absorbed, the photolysis of formaldehyde can contribute one CO2 molecule to the global greenhouse budget or two HO2 radicals to the tropospheric HOx (OH + HO2) cycle. The HO2 radicals produced during formaldehyde photolysis have also been implicated in the formation of photochemical smog. The HO2 radicals act as radical chain carriers and convert NO to NO2, which ultimately results in the catalytic production of O3. Constraining the yield of HO2 produced via HCHO photolysis is essential for improving tropospheric chemistry models. In this study, both the absorption cross section and the quantum yield of the radical channel (R1) were measured at high resolution over the tropospherically relevant wavelength range 304-330 nm. For the cross section measurements a narrow linewidth Nd:YAG pumped dye laser was used with a multi-pass cell. Partial pressures of HCHO were kept below 0.3 torr. Simultaneous measurement of OH LIF in a flame allowed absolute calibration of the wavelength scale. Pressure

  17. High-rate axial-field ionization chamber for particle identification of radioactive beams

    CERN Document Server

    Vadas, J; Visser, G; Alexander, A; Hudan, S; Huston, J; Wiggins, B B; Chbihi, A; Famiano, M; Bischak, M M; deSouza, R T

    2016-01-01

    The design, construction and performance characteristics of a simple axial-field ionization chamber suitable for identifying ions in a radioactive beam are presented. Optimized for use with low-energy radioactive beams (< 5 MeV/A) the detector presents only three 0.5 $\\mu$m/cm$^2$ foils to the beam in addition to the detector gas. A fast charge sensitive amplifier (CSA) integrated into the detector design is also described. Coupling this fast CSA to the axial field ionization chamber produces an output pulse with a risetime of 60-70 ns and a fall time of 100 ns, making the detector capable of sustaining a relatively high rate. Tests with an $\\alpha$ source establish the detector energy resolution as $\\sim$8 $\\%$ for an energy deposit of $\\sim$3.5 MeV. The energy resolution with beams of 2.5 and 4.0 MeV/A $^{39}$K ions and the dependence of the energy resolution on beam intensity is measured. At an instantaneous rate of 3 x 10$^5$ ions/s the energy resolution has degraded to 14% with a pileup of 12%. The go...

  18. The Kenya rift axial gravity high: a re-interpretation

    Science.gov (United States)

    Swain, C. J.

    1992-03-01

    Since KRISP 85 did not provide overwhelming evidence for the massive intrusion that was originally suggested to explain the axial gravity high yet did provide a velocity section for the upper crust along the axis of the Kenya Rift, it is appropriate to use this section to control a re-interpretation of the gravity anomalies. A 2 {1}/{2} D inversion procedure has been used to model a number of isostatic anomaly profiles between Lake Baringo and Suswa. There are too many unknowns and gravity station coverage is too sparse for the results to be unique. Nevertheless, certain conclusions can be drawn. One of those is that some relatively dense material exists within the basement all along the Rift axis, since the axial isostatic anomalies are positive even though they occur where there are several thousand metres of Cenozoic volcanics of relatively low density (inferred from their seismic velocity of 3.7-5.1 km/s). The dense material is envisaged as a zone of dyke injection and assigned a density of 2.75-2.76 g/cm 3 (corresponding to its 6.05 km/s velocity) compared to a normal basement density of 2.70 g/cm 3. It is assumed to extend down to 22 km—the top of the 7.1 km/s layer. The KRISP 85 line passed just east of Menengai, where the basement velocity increases to about 6.6 km/s over a distance of about 20 km. On an east-west gravity profile through Menengai there is a gravity high corresponding to this velocity increase which has been modelled as a basic intrusion (density 2.93 g/cm 3) underlying the caldera.

  19. High resolution digital delay timer

    Science.gov (United States)

    Martin, Albert D.

    1988-01-01

    Method and apparatus are provided for generating an output pulse following a trigger pulse at a time delay interval preset with a resolution which is high relative to a low resolution available from supplied clock pulses. A first lumped constant delay (20) provides a first output signal (24) at predetermined interpolation intervals corresponding to the desired high resolution time interval. Latching circuits (26, 28) latch the high resolution data (24) to form a first synchronizing data set (60). A selected time interval has been preset to internal counters (142, 146, 154) and corrected for circuit propagation delay times having the same order of magnitude as the desired high resolution. Internal system clock pulses (32, 34) count down the counters to generate an internal pulse delayed by an interval which is functionally related to the preset time interval. A second LCD (184) corrects the internal signal with the high resolution time delay. A second internal pulse is then applied to a third LCD (74) to generate a second set of synchronizing data (76) which is complementary with the first set of synchronizing data (60) for presentation to logic circuits (64). The logic circuits (64) further delay the internal output signal (72) to obtain a proper phase relationship of an output signal (80) with the internal pulses (32, 34). The final delayed output signal (80) thereafter enables the output pulse generator (82) to produce the desired output pulse (84) at the preset time delay interval following input of the trigger pulse (10, 12).

  20. High-rate axial-field ionization chamber for particle identification of Radioactive beams

    Science.gov (United States)

    Desouza, Romualdo; Vadas, Justin; Singh, Varinderjit; Visser, G.; Alexander, A.; Hudan, S.; Huston, J.; Wiggins, B.; Chbihi, A.; Famiano, M.; Bischak, M.

    2017-01-01

    The design, construction and performance characteristics of a simple axial-field ionization chamber suitable for identifying ions in a radioactive beam are presented. The detector is optimized for use with low-energy radioactive beams (<) 5 MeV/A. A fast charge sensitive amplifier (CSA) integrated into the detector design is also described. Coupling this fast CSA to the axial field ionization chamber produces an output pulse with a rise-time of 60 to 70 ns and a fall time of 100 ns, making the detector capable of sustaining a relatively high rate while providing a time resolution of 6 to 8 ns. Tests with an α source establish the detector energy resolution as 8 % for an energy deposit of 3.5 MeV. Beam tests indicate that the detector is an effective tool for the characterization of low-energy radioactive beams at beam intensities up to 3 x 105 ions/s. Supported by the U.S. DOE under Award # DE-FG02-88ER-40404 and the NSF under Grant No. 1342962.

  1. High temperature superconducting axial field magnetic coupler: realization and test

    Science.gov (United States)

    Belguerras, L.; Mezani, S.; Lubin, T.; Lévêque, J.; Rezzoug, A.

    2015-09-01

    Contactless torque transmission through a large airgap is required in some industrial applications in which hermetic isolation is necessary. This torque transmission usually uses magnetic couplers, whose dimension strongly depends on the airgap flux density. The use of high temperature superconducting (HTS) coils to create a strong magnetic field may constitute a solution to reduce the size of the coupler. It is also possible to use this coupler to replace a torque tube in transmitting the torque produced by a HTS motor to its load. This paper presents the detailed construction and tests of an axial field HTS magnetic coupler. Pancake coils have been manufactured from BSCCO tape and used in one rotor of the coupler. The second rotor is mainly composed of NdFeB permanent magnets. Several tests have been carried out showing that the constructed coupler is working properly. A 3D finite element (FE) model of the studied coupler has been developed. Airgap magnetic field and torque measurements have been carried out and compared to the FE results. It has been shown that the measured and the computed quantities are in satisfactory agreement.

  2. High Resolution Orientation Imaging Microscopy

    Science.gov (United States)

    2012-05-02

    carbon distribution as it relates to the presence of Bainite phase (with small tetragonality) interspersed among the cubic ferrite. An example of the...preferentially segregate. The view offered by these high resolution methods differs from what has been considered before: grains thought to be Bainite

  3. High-Resolution Instrumentation Radar.

    Science.gov (United States)

    1986-09-30

    30 September 1986 Los Angeles Air Force Station 13. NUMBER OF PAGES Los Angeles, Calif. 90009-2960 36 74. MONITORING AGENCY NAME & ADDRESS(If...TREE PLMUT ",-20 -CUTLIASS DumpER SED AN... TREE TRUNK, -0 - MERC BUMPER f - 40 H!-I -50 iI Fig. 7. High-Resolution Instrumentation Radar View of

  4. Requirements on high resolution detectors

    Energy Technology Data Exchange (ETDEWEB)

    Koch, A. [European Synchrotron Radiation Facility, Grenoble (France)

    1997-02-01

    For a number of microtomography applications X-ray detectors with a spatial resolution of 1 {mu}m are required. This high spatial resolution will influence and degrade other parameters of secondary importance like detective quantum efficiency (DQE), dynamic range, linearity and frame rate. This note summarizes the most important arguments, for and against those detector systems which could be considered. This article discusses the mutual dependencies between the various figures which characterize a detector, and tries to give some ideas on how to proceed in order to improve present technology.

  5. High-resolution second harmonic optical coherence tomography

    Science.gov (United States)

    Jiang, Yi; Tomov, Ivan V.; Wang, Yimin; Chen, Zhongping

    2005-04-01

    A high-resolution Second Harmonic Optical Coherence Tomography (SH-OCT) system is demonstrated using a spectrum broadened femtosecond Ti:sapphire laser. An axial resolution of 4.2 μm at the second harmonic wave center wavelength of 400 nm has been achieved. Because the SH-OCT system uses the second harmonic generation signals that strongly depend on the orientation, polarization and local symmetry properties of chiral molecules, this technique provides unique contrast enhancement to conventional optical coherence tomography. The system is applied to image biological tissues like the rat-tail tendon. Images of highly organized collagen fibrils in the rat-tail tendon have been demonstrated.

  6. High resolution tomographic instrument development

    Energy Technology Data Exchange (ETDEWEB)

    1992-08-01

    Our recent work has concentrated on the development of high-resolution PET instrumentation reflecting in part the growing importance of PET in nuclear medicine imaging. We have developed a number of positron imaging instruments and have the distinction that every instrument has been placed in operation and has had an extensive history of application for basic research and clinical study. The present program is a logical continuation of these earlier successes. PCR-I, a single ring positron tomograph was the first demonstration of analog coding using BGO. It employed 4 mm detectors and is currently being used for a wide range of biological studies. These are of immense importance in guiding the direction for future instruments. In particular, PCR-II, a volume sensitive positron tomograph with 3 mm spatial resolution has benefited greatly from the studies using PCR-I. PCR-II is currently in the final stages of assembly and testing and will shortly be placed in operation for imaging phantoms, animals and ultimately humans. Perhaps the most important finding resulting from our previous study is that resolution and sensitivity must be carefully balanced to achieve a practical high resolution system. PCR-II has been designed to have the detection characteristics required to achieve 3 mm resolution in human brain under practical imaging situations. The development of algorithms by the group headed by Dr. Chesler is based on a long history of prior study including his joint work with Drs. Pelc and Reiderer and Stearns. This body of expertise will be applied to the processing of data from PCR-II when it becomes operational.

  7. High resolution tomographic instrument development

    Energy Technology Data Exchange (ETDEWEB)

    1992-01-01

    Our recent work has concentrated on the development of high-resolution PET instrumentation reflecting in part the growing importance of PET in nuclear medicine imaging. We have developed a number of positron imaging instruments and have the distinction that every instrument has been placed in operation and has had an extensive history of application for basic research and clinical study. The present program is a logical continuation of these earlier successes. PCR-I, a single ring positron tomograph was the first demonstration of analog coding using BGO. It employed 4 mm detectors and is currently being used for a wide range of biological studies. These are of immense importance in guiding the direction for future instruments. In particular, PCR-II, a volume sensitive positron tomograph with 3 mm spatial resolution has benefited greatly from the studies using PCR-I. PCR-II is currently in the final stages of assembly and testing and will shortly be placed in operation for imaging phantoms, animals and ultimately humans. Perhaps the most important finding resulting from our previous study is that resolution and sensitivity must be carefully balanced to achieve a practical high resolution system. PCR-II has been designed to have the detection characteristics required to achieve 3 mm resolution in human brain under practical imaging situations. The development of algorithms by the group headed by Dr. Chesler is based on a long history of prior study including his joint work with Drs. Pelc and Reiderer and Stearns. This body of expertise will be applied to the processing of data from PCR-II when it becomes operational.

  8. HRSC: High resolution stereo camera

    Science.gov (United States)

    Neukum, G.; Jaumann, R.; Basilevsky, A.T.; Dumke, A.; Van Gasselt, S.; Giese, B.; Hauber, E.; Head, J. W.; Heipke, C.; Hoekzema, N.; Hoffmann, H.; Greeley, R.; Gwinner, K.; Kirk, R.; Markiewicz, W.; McCord, T.B.; Michael, G.; Muller, Jan-Peter; Murray, J.B.; Oberst, J.; Pinet, P.; Pischel, R.; Roatsch, T.; Scholten, F.; Willner, K.

    2009-01-01

    The High Resolution Stereo Camera (HRSC) on Mars Express has delivered a wealth of image data, amounting to over 2.5 TB from the start of the mapping phase in January 2004 to September 2008. In that time, more than a third of Mars was covered at a resolution of 10-20 m/pixel in stereo and colour. After five years in orbit, HRSC is still in excellent shape, and it could continue to operate for many more years. HRSC has proven its ability to close the gap between the low-resolution Viking image data and the high-resolution Mars Orbiter Camera images, leading to a global picture of the geological evolution of Mars that is now much clearer than ever before. Derived highest-resolution terrain model data have closed major gaps and provided an unprecedented insight into the shape of the surface, which is paramount not only for surface analysis and geological interpretation, but also for combination with and analysis of data from other instruments, as well as in planning for future missions. This chapter presents the scientific output from data analysis and highlevel data processing, complemented by a summary of how the experiment is conducted by the HRSC team members working in geoscience, atmospheric science, photogrammetry and spectrophotometry. Many of these contributions have been or will be published in peer-reviewed journals and special issues. They form a cross-section of the scientific output, either by summarising the new geoscientific picture of Mars provided by HRSC or by detailing some of the topics of data analysis concerning photogrammetry, cartography and spectral data analysis.

  9. High pressure axial flow fans for modern coal power stations

    Energy Technology Data Exchange (ETDEWEB)

    Cyrus, Vaclav [AHT Energetika s.r.o., Praha (Czech Republic); Koci, Petr [ZVVZ Milevsko a.s. (Czech Republic)

    2008-07-01

    Brown coal fired power stations, located in Northern Bohemia, have mostly older boiler blocks with an output of 110 and 200 MWe. Flue gases are cleaned by the desulphurization plants installed between 1993 and 1997. Usually, each boiler block has two air fans and one to three flue gas fans. Flue gas fans operate in severe conditions; fan blades should be resistant to the flue gases containing sulphur and acid drops with the operating temperature at 170 C to 190 C. Additionally, flue gas also often contains ash particles. Currently, some boiler blocks are gradually being refurbished. New blocks with an electrical power output of 600 to 700 MWe are at the design stage. Submitted paper shows our design study of one stage axial flow fan for the new blocks. Results from the new aerodynamic research of the axial flow stages were used in the fan design. (orig.)

  10. Section on High Resolution Optical Imaging (HROI)

    Data.gov (United States)

    Federal Laboratory Consortium — The Section on High Resolution Optical Imaging (HROI) develops novel technologies for studying biological processes at unprecedented speed and resolution. Research...

  11. Simplified method for ultra high-resolution photoacoustic microscopy via transient absorption.

    Science.gov (United States)

    Mattison, Scott P; Applegate, Brian E

    2014-08-01

    Photoacoustic microscopy (PAM) is a hybrid imaging modality that combines optical illumination with ultrasonic detection to achieve absorption contrast imaging of endogenous and exogenous chromophores. Optical resolution PAM achieves high lateral-resolution by tightly focusing the excitation light; however the axial resolution is still dependent upon the bandwidth of the ultrasonic transducer. As a result, PAM images have highly asymmetric voxels with submicron lateral resolution and axial resolution typically limited to tens of microns. We have previously reported on a resonant multiphoton approach to PAM called transient absorption ultrasonic microscopy (TAUM), which enables high axial resolution by frequency encoding the photoacoustic signal at the overlap of a pump and a probe beam. This approach enables photoacoustic imaging with subcellular resolution on par with other multiphoton microscopy techniques. Here, we report on an innovation that enables TAUM imaging with a much less sophisticated optical system than previously reported. If we allow the time delay between the pump and probe to collapse to zero, the pump and probe optical paths can be combined. An amplitude modulator in the single beam path is sufficient to encode the TAUM signal at the second harmonic of the modulation frequency. The resulting system is essentially a standard optical resolution PAM system that incorporates an amplitude modulator and utilizes a Fourier post processing algorithm to improve the axial resolution by approximately an order of magnitude. A prototype system based on this approach has been assembled and tested on fixed bovine erythrocytes.

  12. High-resolution image analysis.

    Science.gov (United States)

    Preston, K

    1986-01-01

    In many departments of cytology, cytogenetics, hematology, and pathology, research projects using high-resolution computerized microscopy are now being mounted for computation of morphometric measurements on various structural components, as well as for determination of cellular DNA content. The majority of these measurements are made in a partially automated, computer-assisted mode, wherein there is strong interaction between the user and the computerized microscope. At the same time, full automation has been accomplished for both sample preparation and sample examination for clinical determination of the white blood cell differential count. At the time of writing, approximately 1,000 robot differential counting microscopes are in the field, analyzing images of human white blood cells, red blood cells, and platelets at the overall rate of about 100,000 slides per day. This mammoth through-put represents a major accomplishment in the application of machine vision to automated microscopy for hematology. In other areas of automated high-resolution microscopy, such as cytology and cytogenetics, no commercial instruments are available (although a few metaphase-finding machines are available and other new machines have been announced during the past year). This is a disappointing product, considering the nearly half century of research effort in these areas. This paper provides examples of the state of the art in automation of cell analysis for blood smears, cervical smears, and chromosome preparations. Also treated are new developments in multi-resolution automated microscopy, where images are now being generated and analyzed by a single machine over a range of 64:1 magnification and from 10,000 X 20,000 to 500 X 500 in total picture elements (pixels). Examples of images of human lymph node and liver tissue are presented. Semi-automated systems are not treated, although there is mention of recent research in the automation of tissue analysis.

  13. High-Resolution Mass Spectrometers

    Science.gov (United States)

    Marshall, Alan G.; Hendrickson, Christopher L.

    2008-07-01

    Over the past decade, mass spectrometry has been revolutionized by access to instruments of increasingly high mass-resolving power. For small molecules up to ˜400 Da (e.g., drugs, metabolites, and various natural organic mixtures ranging from foods to petroleum), it is possible to determine elemental compositions (CcHhNnOoSsPp…) of thousands of chemical components simultaneously from accurate mass measurements (the same can be done up to 1000 Da if additional information is included). At higher mass, it becomes possible to identify proteins (including posttranslational modifications) from proteolytic peptides, as well as lipids, glycoconjugates, and other biological components. At even higher mass (˜100,000 Da or higher), it is possible to characterize posttranslational modifications of intact proteins and to map the binding surfaces of large biomolecule complexes. Here we review the principles and techniques of the highest-resolution analytical mass spectrometers (time-of-flight and Fourier transform ion cyclotron resonance and orbitrap mass analyzers) and describe some representative high-resolution applications.

  14. Ultra-high resolution AMOLED

    Science.gov (United States)

    Wacyk, Ihor; Prache, Olivier; Ghosh, Amal

    2011-06-01

    AMOLED microdisplays continue to show improvement in resolution and optical performance, enhancing their appeal for a broad range of near-eye applications such as night vision, simulation and training, situational awareness, augmented reality, medical imaging, and mobile video entertainment and gaming. eMagin's latest development of an HDTV+ resolution technology integrates an OLED pixel of 3.2 × 9.6 microns in size on a 0.18 micron CMOS backplane to deliver significant new functionality as well as the capability to implement a 1920×1200 microdisplay in a 0.86" diagonal area. In addition to the conventional matrix addressing circuitry, the HDTV+ display includes a very lowpower, low-voltage-differential-signaling (LVDS) serialized interface to minimize cable and connector size as well as electromagnetic emissions (EMI), an on-chip set of look-up-tables for digital gamma correction, and a novel pulsewidth- modulation (PWM) scheme that together with the standard analog control provides a total dimming range of 0.05cd/m2 to 2000cd/m2 in the monochrome version. The PWM function also enables an impulse drive mode of operation that significantly reduces motion artifacts in high speed scene changes. An internal 10-bit DAC ensures that a full 256 gamma-corrected gray levels are available across the entire dimming range, resulting in a measured dynamic range exceeding 20-bits. This device has been successfully tested for operation at frame rates ranging from 30Hz up to 85Hz. This paper describes the operational features and detailed optical and electrical test results for the new AMOLED WUXGA resolution microdisplay.

  15. Real-time monitoring of high-intensity focused ultrasound treatment using axial strain and axial-shear strain elastograms.

    Science.gov (United States)

    Xia, Rongmin; Thittai, Arun K

    2014-03-01

    Axial strain elastograms (ASEs) have been found to help visualize sonographically invisible thermal lesions. However, in most studies involving high-intensity focused ultrasound (HIFU)-induced thermal lesions, elastography imaging was performed separately later, after the lesion was formed. In this article, the feasibility of monitoring, in real time, tissue elasticity variation during HIFU treatment and immediately thereafter is explored using quasi-static elastography. Further, in addition to ASEs, we also explore the use of simultaneously acquired axial-shear strain elastograms (ASSEs) for HIFU lesion visualization. Experiments were performed on commercial porcine liver samples in vitro. The HIFU experiments were conducted at two applied acoustic power settings, 35 and 20 W. The experimental setup allowed us to interrupt the HIFU pulse momentarily several different times during treatment to perform elastographic compression and data acquisition. At the end of the experiments, the samples were cut along the imaging plane and photographed to compare size and location of the formed lesion with those visualized on ASEs and ASSEs. Single-lesion and multiple-lesion experiments were performed to assess the contribution of ASEs and ASSEs to lesion visualization and treatment monitoring tasks. At both power settings, ASEs and ASSEs provided accurate location information during HIFU treatment. At the low-power setting case, ASEs and ASSEs provide accurate lesion size in real-time monitoring. Lesion appearance in ASEs and ASSEs was affected by the cavitation bubbles produced at the high-power setting. The results further indicate that the cavitation bubbles influence lesion appearance more in ASEs than in ASSEs. Both ASEs and ASSEs provided accurate size information after a waiting period that allowed the cavitation bubbles to disappear. The results indicate that ASSEs not only improve lesion visualization and size measurement of a single lesion, but, under certain

  16. High-resolution slug testing.

    Science.gov (United States)

    Zemansky, G M; McElwee, C D

    2005-01-01

    The hydraulic conductivity (K) variation has important ramifications for ground water flow and the transport of contaminants in ground water. The delineation of the nature of that variation can be critical to complete characterization of a site and the planning of effective and efficient remedial measures. Site-specific features (such as high-conductivity zones) need to be quantified. Our alluvial field site in the Kansas River valley exhibits spatial variability, very high conductivities, and nonlinear behavior for slug tests in the sand and gravel aquifer. High-resolution, multilevel slug tests have been performed in a number of wells that are fully screened. A general nonlinear model based on the Navier-Stokes equation, nonlinear frictional loss, non-Darcian flow, acceleration effects, radius changes in the wellbore, and a Hvorslev model for the aquifer has been used to analyze the data, employing an automated processing system that runs within the Excel spreadsheet program. It is concluded that slug tests can provide the necessary data to identify the nature of both horizontal and vertical K variation in an aquifer and that improved delineation or higher resolution of K structure is possible with shorter test intervals. The gradation into zones of higher conductivity is sharper than seen previously, and the maximum conductivity observed is greater than previously measured. However, data from this project indicate that well development, the presence of fines, and the antecedent history of the well are important interrelated factors in regard to slug-test response and can prevent obtaining consistent results in some cases.

  17. High Spatiotemporal Resolution Prostate MRI

    Science.gov (United States)

    2016-09-01

    for time- resolved contrast-enhanced MR angiography (CE-MRA) using two-dimensional (2D) SENSE acceleration (10). For this work the slab ...orientation was approximately axial but with slight forward tilting to align the slab select direction with the central axis of the prostate gland as... composite images was then provided to each reviewer. The two radiologist reviewers (ATF, five years experience in prostate MRI; AK, 20 years

  18. High-resolution land topography

    Science.gov (United States)

    Massonnet, Didier; Elachi, Charles

    2006-11-01

    After a description of the background, methods of production and some scientific uses of high-resolution land topography, we present the current status and the prospect of radar interferometry, regarded as one of the best techniques for obtaining the most global and the most accurate topographic maps. After introducing briefly the theoretical aspects of radar interferometry - principles, limits of operation and various capabilities -, we will focus on the topographic applications that resulted in an almost global topographic map of the earth: the SRTM map. After introducing the Interferometric Cartwheel system, we will build on its expected performances to discuss the scientific prospects of refining a global topographic map to sub-metric accuracy. We also show how other fields of sciences such as hydrology may benefit from the products generated by interferometric radar systems. To cite this article: D. Massonnet, C. Elachi, C. R. Geoscience 338 (2006).

  19. High-precision efficiency calibration of a high-purity co-axial germanium detector

    Energy Technology Data Exchange (ETDEWEB)

    Blank, B., E-mail: blank@cenbg.in2p3.fr [Centre d' Etudes Nucléaires de Bordeaux Gradignan, UMR 5797, CNRS/IN2P3, Université de Bordeaux, Chemin du Solarium, BP 120, 33175 Gradignan Cedex (France); Souin, J.; Ascher, P.; Audirac, L.; Canchel, G.; Gerbaux, M.; Grévy, S.; Giovinazzo, J.; Guérin, H.; Nieto, T. Kurtukian; Matea, I. [Centre d' Etudes Nucléaires de Bordeaux Gradignan, UMR 5797, CNRS/IN2P3, Université de Bordeaux, Chemin du Solarium, BP 120, 33175 Gradignan Cedex (France); Bouzomita, H.; Delahaye, P.; Grinyer, G.F.; Thomas, J.C. [Grand Accélérateur National d' Ions Lourds, CEA/DSM, CNRS/IN2P3, Bvd Henri Becquerel, BP 55027, F-14076 CAEN Cedex 5 (France)

    2015-03-11

    A high-purity co-axial germanium detector has been calibrated in efficiency to a precision of about 0.15% over a wide energy range. High-precision scans of the detector crystal and γ-ray source measurements have been compared to Monte-Carlo simulations to adjust the dimensions of a detector model. For this purpose, standard calibration sources and short-lived online sources have been used. The resulting efficiency calibration reaches the precision needed e.g. for branching ratio measurements of super-allowed β decays for tests of the weak-interaction standard model.

  20. The Effect of Amplitude Modulation on the Axial Resolution of Doppler-Based Ultrasonic Topography Measurement

    DEFF Research Database (Denmark)

    RezaNejad Gatabi, Javad; Das, Sayantan; Forouzbakhsh, Farshid

    2016-01-01

    of the Doppler measurement techniques. A modified Doppler measurement system that significantly improves the measurement accuracy is also presented. The fabricated sensor has 72-μm measurement accuracy using 40-kHz transducers. This technique can also be employed in cost-effective displacement measurement...... variation of the received signal. Amplitude variation significantly affects the measurement accuracy when the surface axial displacement range is comparable with the ultrasonic wavelength. This paper presents a theoretical and experimental study of the effect of amplitude modulation on the performance......Ultrasonic Doppler-based systems for surface topography measurements are attractive alternatives to the transit-time-based methods. Sensors used in Doppler systems are less dependent on the speed of the sound in air, although contemporary Doppler measurement systems are sensitive to the amplitude...

  1. High resolution emission tomography; Tomographie d`emission haute resolution

    Energy Technology Data Exchange (ETDEWEB)

    Charon, Y.; Laniece, P.; Mastrippolito, R.; Pinot, L.; Ploux, L.; Valda Ochoa, A.; Valentin, L. [Groupe I.P.B., Experimental Research Division, Inst. de Physique Nucleaire, Paris-11 Univ., 91 - Orsay (France)

    1999-11-01

    We have developed an original high resolution tomograph for in-vivo small animal imaging. A first prototype is under evaluation. Initial results of its characterisation are presented. (authors) 3 figs.

  2. Axial power monitor rod issues and resolution for K-14.1

    Energy Technology Data Exchange (ETDEWEB)

    Easterling, T.C.; Fields, C.C.; Hightower, N.T. III; Wooten, L.A. [eds.; Andre, S.K.; Apperson, C.E.; Bailey, M.H.; Bell, D.L.; Clare, G.H.; Collins, S.L.; Croft, W.D.; Edwards, T.B.; Geiger, G.T.; Harris, S.P.; Lietzow, J.L.; McCulloch, R.W.; McFarlane, A.F.; Randolph, H.W.; Reed, R.L.; Reeve, C.P.; Revolinski, S.M.; Sessions, H.T.; Shine, E.P.; Smith, T.A.; Sossman, C.L.; Taylor, J.J.; Weber, J.H.

    1992-05-01

    A recent concern arose over the treatment of uncertainty associated with the K-Reactor axial power monitors (APMs). There are nine axial power monitor rods located at various positions in the K-Reactor core. By comparing the output of one sensor near the top of the rod to the output of another sensor near the bottom of the rod, the relative ratio of the neutron flux from the top to the bottom of the core can be determined. This ratio is called the roof-top-ratio (RTR) and is the output of a top sensor (Sensor 2) divided by the output of a bottom sensor (Sensor 6). The RTR is important to the safety analyses because when the RTR is maintained within certain ranges, the severity of reactivity transients is limited. There are uncertainties associated with the equipment`s ability to measure the true roof top ratio. It was determined recently that sufficient uncertainty was not accounted for either in reactor operation or in the safety analyses. The concern about uncertainty was addressed for three separate issues. One issue dear with the linear response of the sensors for power ranges planned for K-Reactor operation. The second issue dear with overall uncertainty in the RTR channel. The third issue dear with apparent large ranges in confidence bands for the RTR at low reactor powers as represented by original vendor data. Plots of sparse vendor data indicated unacceptably large uncertainties in RTR would have to be accounted for at the power ranges planned for K-Reactor operation. These concerns were brought to management`s attention through the existing procedures for notification, irrespective of their potential impact on the restart schedule. Analyses have been completed to resolve the APM issues described above, and work is progressing to take the needed steps to change operational procedures.

  3. High-throughput in-volume processing in glass with isotropic spatial resolutions in three dimensions

    CERN Document Server

    Tan, Yuanxin; Chu, Wei; Liao, Yang; Qiao, Lingling; Cheng, Ya

    2016-01-01

    We report on fabrication of three dimensional (3D) microstructures in glass with isotropic spatial resolutions. To achieve high throughput fabrication, we expand the focal spot size with a low-numerical-aperture lens, which naturally results in a degraded axial resolution. We solve the problem with simultaneous spatial temporal focusing which leads to an isotropic laser-affected volume with a spatial resolution of ~100 micron.

  4. VT Hydrography Dataset - High Resolution NHD

    Data.gov (United States)

    Vermont Center for Geographic Information — (Link to Metadata) The Vermont Hydrography Dataset (VHD) is compliant with the local resolution (also known as High Resolution) National Hydrography Dataset (NHD)...

  5. High-resolution infrared imaging

    Science.gov (United States)

    Falco, Charles M.

    2010-08-01

    The hands and mind of an artist are intimately involved in the creative process of image formation, intrinsically making paintings significantly more complex than photographs to analyze. In spite of this difficulty, several years ago the artist David Hockney and I identified optical evidence within a number of paintings that demonstrated artists began using optical projections as early as c1425 - nearly 175 years before Galileo - as aids for producing portions of their images. In the course of our work, Hockney and I developed insights that I have been applying to a new approach to computerized image analysis. Recently I developed and characterized a portable high resolution infrared for capturing additional information from paintings. Because many pigments are semi-transparent in the IR, in a number of cases IR photographs ("reflectograms") have revealed marks made by the artists that had been hidden under paint ever since they were made. I have used this IR camera to capture photographs ("reflectograms") of hundreds of paintings in over a dozen museums on three continents and, in some cases, these reflectograms have provided new insights into decisions the artists made in creating the final images that we see in the visible.

  6. High-resolution neutron tomography

    Energy Technology Data Exchange (ETDEWEB)

    Mikerov, V.I. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Zhitnik, I.A. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Ignat`ev, A.P. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Isakov, A.I. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Korneev, V.V. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Krutov, V.V. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Kuzin, S.V. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Oparin, S.N. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Pertsov, A.A. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Podolyak, E.R. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Sobel`man, I.I. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Tindo, I.P. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation); Tukarev, B.A. [P.N. Lebedev Physical Inst., RAN, Moscow (Russian Federation)

    1995-12-31

    A neutron tomography technique with a coordinate resolution of several tens of micrometers has been developed. Our results indicate that the technique resolves details with dimensions less than 100 {mu}m and measures a linear attenuation of less than {approx} 0.1 cm{sup -1}. Tomograms can be reconstructed using incomplete data. Limits on the resolution of the restored pattern are analyzed, and ways to improve the sensitivity of the technique are discussed. (orig.).

  7. High Efficiency Axial Deep Creep-Feed Grinding Machining Technology of Engineering Ceramics Materials

    Institute of Scientific and Technical Information of China (English)

    GUO Fang; ZHANG Baoguo; LU Hong; TIAN Xinli; WANG Jianquan; LI Fuqiang

    2012-01-01

    Axial deep creep-feed grinding machining technology is a high efficiency process method of engineering ceramics materials,which is an original method to process the cylindrical ceramics materials or hole along its axis.The analysis of axial force and edge fracture proved the cutting thickness and feed rate could be more than 5-10 mm and 200 mm/min respectively in once process,and realized high efficiency,low-cost process of engineering ceramics materials.Compared with high speed-deep grinding machining,this method is also a high efficiency machining technology of engineering ceramics materials as well as with low cost.In addition,removal mechanism analyses showed that both median/radial cracks and lateral cracks appeared in the part to be removed,and the processed part is seldom destroyed,only by adjusting the axial force to control the length of transverse cracks.

  8. High-resolution electron microscopy

    CERN Document Server

    Spence, John C H

    2013-01-01

    This new fourth edition of the standard text on atomic-resolution transmission electron microscopy (TEM) retains previous material on the fundamentals of electron optics and aberration correction, linear imaging theory (including wave aberrations to fifth order) with partial coherence, and multiple-scattering theory. Also preserved are updated earlier sections on practical methods, with detailed step-by-step accounts of the procedures needed to obtain the highest quality images of atoms and molecules using a modern TEM or STEM electron microscope. Applications sections have been updated - these include the semiconductor industry, superconductor research, solid state chemistry and nanoscience, and metallurgy, mineralogy, condensed matter physics, materials science and material on cryo-electron microscopy for structural biology. New or expanded sections have been added on electron holography, aberration correction, field-emission guns, imaging filters, super-resolution methods, Ptychography, Ronchigrams, tomogr...

  9. DESIR high resolution separator at GANIL, France

    Directory of Open Access Journals (Sweden)

    Toprek Dragan

    2012-01-01

    Full Text Available A high-resolution separator for the SPIRAL2/DESIR project at GANIL has been designed. The extracted isotopes from SPIRAL2 will be transported to and cooled in a RFQ cooler yielding beams with very low transverse emittance and energy spread. These beams will then be accelerated to 60 keV and sent to a high-resolution mass separator where a specific isotope will be selected. The good beam properties extracted from the RFQ cooler will allow one to obtain a mass resolution of č26000 with the high-resolution mass separator.

  10. The concept of a plasma centrifuge with a high frequency rotating magnetic field and axial circulation

    Science.gov (United States)

    Borisevich, V. D.; Potanin, E. P.

    2017-07-01

    The possibility of using a rotating magnetic field (RMF) in a plasma centrifuge (PC), with axial circulation to multiply the radial separation effect in an axial direction, is considered. For the first time, a traveling magnetic field (TMF) is proposed to drive an axial circulation flow in a PC. The longitudinal separation effect is calculated for a notional model, using specified operational parameters and the properties of a plasma, comprising an isotopic mixture of 20Ne-22Ne and generated by a high frequency discharge. The optimal intensity of a circulation flow, in which the longitudinal separation effect reaches its maximum value, is studied. The optimal parameters of the RMF and TMF for effective separation, as well as the centrifuge performance, are calculated.

  11. Dynamic coefficients of axial spline couplings in high-speed rotating machinery

    Energy Technology Data Exchange (ETDEWEB)

    Ku, C.P.R.; Walton, J.F. Jr. (Mechanical Technology Inc., Latham, NY (United States)); Lund, J.W. (Technical Univ. of Denmark, Lyngby (Denmark). Dept. of Machine Elements)

    1994-07-01

    This paper provided the first opportunity to quantify the angular stiffness and equivalent viscous damping coefficients of an axial spline coupling used in high-speed turbomachinery. The bending moments and angular deflections transmitted across an axial spline coupling were measured while a nonrotating shaft was excited by an external shaker. A rotordynamics computer program was used to simulate the test conditions and to correlate the angular stiffness and damping coefficients. The effects of external force and frequency were also investigated. The angular stiffness and damping coefficients were used to perform a linear steady-state rotordynamics stability analysis, and the unstable natural frequency was calculated and compared to the experimental measurements.

  12. High-resolution retinal imaging using adaptive optics and Fourier-domain optical coherence tomography

    Science.gov (United States)

    Olivier, Scot S.; Werner, John S.; Zawadzki, Robert J.; Laut, Sophie P.; Jones, Steven M.

    2010-09-07

    This invention permits retinal images to be acquired at high speed and with unprecedented resolution in three dimensions (4.times.4.times.6 .mu.m). The instrument achieves high lateral resolution by using adaptive optics to correct optical aberrations of the human eye in real time. High axial resolution and high speed are made possible by the use of Fourier-domain optical coherence tomography. Using this system, we have demonstrated the ability to image microscopic blood vessels and the cone photoreceptor mosaic.

  13. Overview spectra and axial distribution of spectral line intensities in a high-current vacuum arc with CuCr electrodes

    Energy Technology Data Exchange (ETDEWEB)

    Lisnyak, M.; Pipa, A. V.; Gorchakov, S., E-mail: gorchakov@inp-greifswald.de, E-mail: weltmann@inp-greifswald.de; Iseni, S.; Franke, St.; Khapour, A.; Methling, R.; Weltmann, K.-D., E-mail: gorchakov@inp-greifswald.de, E-mail: weltmann@inp-greifswald.de [Leibniz-Institut für Plasmaforschung und Technologie e.V., Felix-Hausdorff-Straße 2, 17489 Greifswald (Germany)

    2015-09-28

    Spectroscopic investigations of free-burning vacuum arcs in diffuse mode with CuCr electrodes are presented. The experimental conditions of the investigated arc correspond to the typical system for vacuum circuit breakers. Spectra of six species Cu I, Cu II, Cu III, Cr I, Cr II, and Cr III have been analyzed in the wavelength range 350–810 nm. The axial intensity distributions were found to be strongly dependent on the ionization stage of radiating species. Emission distributions of Cr II and Cu II can be distinguished as well as the distributions of Cr III and Cu III. Information on the axial distribution was used to identify the spectra and for identification of overlapping spectral lines. The overview spectra and some spectral windows recorded with high resolution are presented. Analysis of axial distributions of emitted light, which originates from different ionization states, is presented and discussed.

  14. High Resolution Silicon Deformable Mirrors Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This proposal describes a plan to build a prototype small stroke, high precision deformable mirror suitable for space-based operation in systems for high-resolution...

  15. High-Resolution Data for a Low-Resolution World

    Energy Technology Data Exchange (ETDEWEB)

    Brady, Brendan Williams [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-05-10

    In the past 15 years, the upper section of Cañon de Valle has been severely altered by wildfires and subsequent runoff events. Loss of root structures on high-angle slopes results in debris flow and sediment accumulation in the narrow canyon bottom. The original intent of the study described here was to better understand the changes occurring in watershed soil elevations over the course of several post-fire years. An elevation dataset from 5 years post-Cerro Grande fire was compared to high-resolution LiDAR data from 14 years post-Cerro Grande fire (also 3 years post-Las Conchas fire). The following analysis was motivated by a problematic comparison of these datasets of unlike resolution, and therefore focuses on what the data reveals of itself. The objective of this study is to highlight the effects vegetation can have on remote sensing data that intends to read ground surface elevation.

  16. Standard high-resolution pelvic MRI vs. low-resolution pelvic MRI in the evaluation of deep infiltrating endometriosis

    Energy Technology Data Exchange (ETDEWEB)

    Scardapane, Arnaldo; Lorusso, Filomenamila; Ferrante, Annunziata; Stabile Ianora, Amato Antonio; Angelelli, Giuseppe [University Hospital ' ' Policlinico' ' of Bari, Interdisciplinary Department of Medicine, Bari (Italy); Scioscia, Marco [Sacro Cuore Don Calabria General Hospital, Department of Obstetrics and Gynecology, Negrar, Verona (Italy)

    2014-10-15

    To compare the capabilities of standard pelvic MRI with low-resolution pelvic MRI using fast breath-hold sequences to evaluate deep infiltrating endometriosis (DIE). Sixty-eight consecutive women with suspected DIE were studied with pelvic MRI. A double-acquisition protocol was carried out in each case. High-resolution (HR)-MRI consisted of axial, sagittal, and coronal TSE T2W images, axial TSE T1W, and axial THRIVE. Low-resolution (LR)-MRI was acquired using fast single shot (SSH) T2 and T1 images. Two radiologists with 10 and 2 years of experience reviewed HR and LR images in two separate sessions. The presence of endometriotic lesions of the uterosacral ligament (USL), rectovaginal septum (RVS), pouch of Douglas (POD), and rectal wall was noted. The accuracies of LR-MRI and HR-MRI were compared with the laparoscopic and histopathological findings. Average acquisition times were 24 minutes for HR-MRI and 7 minutes for LR-MRI. The more experienced radiologist achieved higher accuracy with both HR-MRI and LR-MRI. The values of sensitivity, specificity, PPV, NPV, and accuracy did not significantly change between HR and LR images or interobserver agreement for all of the considered anatomic sites. LR-MRI performs as well as HR-MRI and is a valuable tool for the detection of deep endometriosis extension. (orig.)

  17. Research on a novel high stiffness axial passive magnetic bearing for DGMSCMG

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Jinji [Key Laboratory of Fundamental Science for National Defense, Novel Inertial Instrument and Navigation System Technology, School of Instrument Science and Opto-electronics Engineering, Beihang University, 100191 (China); Wang, Chun' e [Beijing Institute of Automatic Control Equipment, 100074 (China); Le, Yun [Key Laboratory of Fundamental Science for National Defense, Novel Inertial Instrument and Navigation System Technology, School of Instrument Science and Opto-electronics Engineering, Beihang University, 100191 (China)

    2016-08-15

    To increase the displacement stiffness and decrease power loss of double gimbals magnetically suspended control momentum gyro (DGMSCMG), this paper researches a new structure of axial passive magnetic bearing (APMB). Different from the existing APMB, the proposed APMB is composed of segmented permanent magnets and magnetic rings. The displacement stiffness and angular stiffness expressions are derived by equivalent magnetic circuit method and infinitesimal method based on the end magnetic flux. The relationships are analyzed between stiffness and structure parameters such as length of air gap, length of permanent magnet, height of permanent magnet and end length of magnetic ring. Besides, the axial displacement stiffness measurement method of the APMB is proposed, and it verified the correctness of proposed theoretical method. The DGMSCMG prototype is manufactured and the slow-down characteristic experiment is carried out, and the experimental result reflects the low power loss feature of the APMB. - Highlights: • A novel high stiffness axial passive magnetic bearing for DGMSCMG. • The proposed APMB is composed of segmented permanent magnets and magnetic rings. • The APMB is analyzed by EMCM and infinitesimal method based on the end magnetic flux. • The axial displacement stiffness measurement method of the APMB is proposed. • The DGMSCMG is manufactured and proved the correctness of theoretical analysis.

  18. High-speed measurement of axial grain transport in a rotating drum

    Science.gov (United States)

    van Bussel, Frank; Khan, Zeina; Schaber, Marc; Seemann, Ralf; Scheel, Mario; Dimichiel, Marco

    2012-02-01

    Over short timescales granular mixtures separate by size when tumbled in a partially filled horizontal drum. The smaller grains move toward the axis of rotation to form a central core; undulations in this core gradually increase in amplitude until they grow into axial bands. Using non-invasive high-speed synchrotron x-ray particle tracking, we investigate the axial transport properties of tracer particles traveling amongst glass spheres. This new technique allows us to gather data on time scales not previously possible. When the tracers are present in larger proportions the mixtures we used should have different tendencies to segregate axially according to size ratio; one of our findings, however, is that when the tracer concentration is low the single-particle dynamics of these mixtures do not depend on the relative particle sizes in any appreciable way. This implies that the potential for a mixture to axially segregate cannot be inferred from the microscopic dynamics of individual small particles. A second finding is that while the slope of the mean-squared displacement is close to that expected from diffusive transport, as determined from the single-particle dynamics, more detailed analyses indicate anomalous transport.

  19. Analysis of a Liquid Nitrogen-Cooled Tri-Axial High-Temperature Superconducting Cable System

    Science.gov (United States)

    Demko, J. A.; Lue, J. W.; Gouge, M. J.; Fisher, P. W.; Lindsay, D.; Roden, M.

    2004-06-01

    This tri-axial high-temperature superconducting (HTS) cable design uses three concentric superconducting layers for the phase conductors, separated by a cold dielectric material. The design offers an efficient HTS cable configuration by reducing the amount of superconductor needed and places all three phases in a single cryostat. The tri-axial cable cooling circuit analyzed includes heat loads at the ends for the cable terminations and cable heat loads due to ac, dielectric, and thermal losses. The HTS cable critical current and ac loss are functions of the local temperature that must be determined by the analysis. The radial heat transfer also has an influence on these parameters due to the relatively low thermal conductivity of the dielectric material separating the HTS phases. The study investigates whether the tri-axial cable must be cooled both inside the former and outside of the cable. In this study, the range of operating parameters for a tri-axial HTS cable system and refrigeration requirements are determined based on expected HTS tape performance.

  20. High resolution studies of massive primordial haloes

    CERN Document Server

    Latif, M A; Schmidt, W; Niemeyer, J

    2012-01-01

    Atomic cooling haloes with T_vir > 10^4 K are the most plausible sites for the formation of the first galaxies. In this article, we aim to study the implications of gravity driven turbulence in protogalactic haloes. By varying the resolution per Jeans length, we explore whether the turbulent cascade is resolved well enough to obtain converged results. We have performed high resolution cosmological simulations using the adaptive mesh refinement code Enzo including a subgrid-scale turbulence model to study the role of unresolved turbulence. We compared the results of three different Jeans resolutions from 16 to 64 cells. While radially averaged profiles roughly agree at different resolutions, differences in the morphology reveal that even the highest resolution employed provides no convergence. Moreover, taking into account unresolved turbulence significantly influences the morphology of a halo. We have quantified the properties of the high-density clumps in the halo. These clumps are gravitationally unbound wi...

  1. High Resolution Silicon Deformable Mirrors Project

    Data.gov (United States)

    National Aeronautics and Space Administration — In this proposal we describe a plan to build a deformable mirror suitable for space-based operation in systems for high-resolution imaging. The prototype DM will be...

  2. High range resolution micro-Doppler analysis

    Science.gov (United States)

    Cammenga, Zachary A.; Smith, Graeme E.; Baker, Christopher J.

    2015-05-01

    This paper addresses use of the micro-Doppler effect and the use of high range-resolution profiles to observe complex targets in complex target scenes. The combination of micro-Doppler and high range-resolution provides the ability to separate the motion of complex targets from one another. This ability leads to the differentiation of targets based on their micro-Doppler signatures. Without the high-range resolution, this would not be possible because the individual signatures would not be separable. This paper also addresses the use of the micro-Doppler information and high range-resolution profiles to generate an approximation of the scattering properties of a complex target. This approximation gives insight into the structure of the complex target and, critically, is created without using a pre-determined target model.

  3. Structure of high-resolution NMR spectra

    CERN Document Server

    Corio, PL

    2012-01-01

    Structure of High-Resolution NMR Spectra provides the principles, theories, and mathematical and physical concepts of high-resolution nuclear magnetic resonance spectra.The book presents the elementary theory of magnetic resonance; the quantum mechanical theory of angular momentum; the general theory of steady state spectra; and multiple quantum transitions, double resonance and spin echo experiments.Physicists, chemists, and researchers will find the book a valuable reference text.

  4. The numerical simulation of a high-speed axial flow compressor

    Science.gov (United States)

    Mulac, Richard A.; Adamczyk, John J.

    1991-01-01

    The advancement of high-speed axial-flow multistage compressors is impeded by a lack of detailed flow-field information. Recent development in compressor flow modeling and numerical simulation have the potential to provide needed information in a timely manner. The development of a computer program is described to solve the viscous form of the average-passage equation system for multistage turbomachinery. Programming issues such as in-core versus out-of-core data storage and CPU utilization (parallelization, vectorization, and chaining) are addressed. Code performance is evaluated through the simulation of the first four stages of a five-stage, high-speed, axial-flow compressor. The second part addresses the flow physics which can be obtained from the numerical simulation. In particular, an examination of the endwall flow structure is made, and its impact on blockage distribution assessed.

  5. High-resolution MR imaging of the normal rotator cuff.

    Science.gov (United States)

    Middleton, W D; Kneeland, J B; Carrera, G F; Cates, J D; Kellman, G M; Campagna, N G; Jesmanowicz, A; Froncisz, W; Hyde, J S

    1987-03-01

    The shoulders of six normal volunteers were imaged with high-resolution MR in the axial, sagittal, and coronal planes. An angled pair of counter-rotating current loop-gap resonators designed specifically for the shoulder was used as a local coil. All images were compared with corresponding cryomicrotome sections from cadaver shoulders. The rotator cuff was analyzed in detail. It appeared as a complex, heterogeneous band to tissue superficial to the humeral head. The areas of low signal intensity corresponded to the central tendons of the four rotator cuff muscles. These tendons could be distinguished from each other as well as from the intervening components of the cuff, which have a moderate intensity. We concluded that MR is capable of imaging the normal rotator cuff and of separating the various components. This may allow for improved precision in the diagnosis of rotator cuff disorders.

  6. High resolution SAR applications and instrument design

    Science.gov (United States)

    Dionisio, C.; Torre, A.

    1993-01-01

    The Synthetic Aperture Radar (SAR) has viewed, in the last two years, a huge increment of interest from many preset and potential users. The good spatial resolution associated to the all weather capability lead to considering SAR not only a scientific instrument but a tool for verifying and controlling the daily human relationships with the Earth Environment. New missions were identified for SAR as spatial resolution became lower than three meters: disasters, pollution, ships traffic, volcanic eruptions, earthquake effect are only a few of the possible objects which can be effectively detected, controlled and monitored by SAR mounted on satellites. High resolution radar design constraints and dimensioning are discussed.

  7. 4MOST: the high-resolution spectrograph

    Science.gov (United States)

    Seifert, W.; Xu, W.; Buschkamp, P.; Feiz, C.; Saviauk, A.; Barden, S.; Quirrenbach, A.; Mandel, H.

    2016-08-01

    4MOST (4-meter Multi-Object Spectroscopic Telescope) is a wide-field, fiber-feed, high-multiplex spectroscopic survey facility to be installed on the 4-meter ESO telescope VISTA in Chile. It consists of two identical low resolution spectrographs and one high resolution spectrograph. The instrument is presently in the preliminary design phase and expected to get operational end of 2022. The high resolution spectrograph will afford simultaneous observations of up to 812 targets - over a hexagonal field of view of 4.1 sq.degrees on sky - with a spectral resolution R>18,000 covering a wavelength range from 393 to 679nm in three channels. In this paper we present the optical and mechanical design of the high resolution spectrograph (HRS) as prepared for the review at ESO, Garching. The expected performance including the highly multiplexed fiber slit concept is simulated and its impact on the optical performance given. We show the thermal and finite element analyses and the resulting stability of the spectrograph under operational conditions.

  8. High-Resolution PET Detector. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Karp, Joel

    2014-03-26

    The objective of this project was to develop an understanding of the limits of performance for a high resolution PET detector using an approach based on continuous scintillation crystals rather than pixelated crystals. The overall goal was to design a high-resolution detector, which requires both high spatial resolution and high sensitivity for 511 keV gammas. Continuous scintillation detectors (Anger cameras) have been used extensively for both single-photon and PET scanners, however, these instruments were based on NaI(Tl) scintillators using relatively large, individual photo-multipliers. In this project we investigated the potential of this type of detector technology to achieve higher spatial resolution through the use of improved scintillator materials and photo-sensors, and modification of the detector surface to optimize the light response function.We achieved an average spatial resolution of 3-mm for a 25-mm thick, LYSO continuous detector using a maximum likelihood position algorithm and shallow slots cut into the entrance surface.

  9. Surface nanoscale axial photonics: Robust fabrication of high quality factor microresonators

    CERN Document Server

    Sumetsky, M; Dulashko, Y; Fini, J M; Liu, X; Monberg, E M; Taunay, T F

    2011-01-01

    Recently introduced Surface Nanoscale Axial Photonics (SNAP) makes it possible to fabricate high Q-factor microresonators and other photonic microdevices by dramatically small deformation of the optical fiber surface. To become a practical and robust technology, the SNAP platform requires methods enabling reproducible modification of the optical fiber radius at nanoscale. In this Letter, we demonstrate super-accurate fabrication of high Q-factor microresonators by nanoscale modification of the optical fiber radius and refractive index using the CO2 laser and the UV excimer laser beam exposures. The achieved fabrication accuracy is better than 2 angstroms in variation of the effective fiber radius.

  10. A High Resolution Scale-of-four

    Science.gov (United States)

    Fitch, V.

    1949-08-25

    A high resolution scale-of-four has been developed to be used in conjunction with the nuclear particle detection devices in applications where the counting rate is unusually high. Specifically, it is intended to precede the commercially available medium resolution scaling circuits and so decrease the resolving time of the counting system. The circuit will function reliably on continuously recurring pulses separated by less than 0.1 microseconds. It will resolve two pulses (occurring at a moderate repetition rate) which are spaced at 0.04 microseconds. A five-volt input signal is sufficient to actuate the device.

  11. Single shot high resolution digital holography.

    Science.gov (United States)

    Khare, Kedar; Ali, P T Samsheer; Joseph, Joby

    2013-02-11

    We demonstrate a novel computational method for high resolution image recovery from a single digital hologram frame. The complex object field is obtained from the recorded hologram by solving a constrained optimization problem. This approach which is unlike the physical hologram replay process is shown to provide high quality image recovery even when the dc and the cross terms in the hologram overlap in the Fourier domain. Experimental results are shown for a Fresnel zone hologram of a resolution chart, intentionally recorded with a small off-axis reference beam angle. Excellent image recovery is observed without the presence of dc or twin image terms and with minimal speckle noise.

  12. Customized MFM probes with high lateral resolution

    Directory of Open Access Journals (Sweden)

    Óscar Iglesias-Freire

    2016-07-01

    Full Text Available Magnetic force microscopy (MFM is a widely used technique for magnetic imaging. Besides its advantages such as the high spatial resolution and the easy use in the characterization of relevant applied materials, the main handicaps of the technique are the lack of control over the tip stray field and poor lateral resolution when working under standard conditions. In this work, we present a convenient route to prepare high-performance MFM probes with sub-10 nm (sub-25 nm topographic (magnetic lateral resolution by following an easy and quick low-cost approach. This allows one to not only customize the tip stray field, avoiding tip-induced changes in the sample magnetization, but also to optimize MFM imaging in vacuum (or liquid media by choosing tips mounted on hard (or soft cantilevers, a technology that is currently not available on the market.

  13. High-resolution electrohydrodynamic jet printing

    Science.gov (United States)

    Park, Jang-Ung; Hardy, Matt; Kang, Seong Jun; Barton, Kira; Adair, Kurt; Mukhopadhyay, Deep Kishore; Lee, Chang Young; Strano, Michael S.; Alleyne, Andrew G.; Georgiadis, John G.; Ferreira, Placid M.; Rogers, John A.

    2007-10-01

    Efforts to adapt and extend graphic arts printing techniques for demanding device applications in electronics, biotechnology and microelectromechanical systems have grown rapidly in recent years. Here, we describe the use of electrohydrodynamically induced fluid flows through fine microcapillary nozzles for jet printing of patterns and functional devices with submicrometre resolution. Key aspects of the physics of this approach, which has some features in common with related but comparatively low-resolution techniques for graphic arts, are revealed through direct high-speed imaging of the droplet formation processes. Printing of complex patterns of inks, ranging from insulating and conducting polymers, to solution suspensions of silicon nanoparticles and rods, to single-walled carbon nanotubes, using integrated computer-controlled printer systems illustrates some of the capabilities. High-resolution printed metal interconnects, electrodes and probing pads for representative circuit patterns and functional transistors with critical dimensions as small as 1μm demonstrate potential applications in printed electronics.

  14. Smartphone microendoscopy for high resolution fluorescence imaging

    CERN Document Server

    Hong, Xiangqian; Mugler, Dale H; Yu, Bing

    2016-01-01

    High resolution optical endoscopes are increasingly used in diagnosis of various medical conditions of internal organs, such as the gastrointestinal tracts, but they are too expensive for use in resource-poor settings. On the other hand, smartphones with high resolution cameras and Internet access have become more affordable, enabling them to diffuse into most rural areas and developing countries in the past decade. In this letter we describe a smartphone microendoscope that can take fluorescence images with a spatial resolution of 3.1 {\\mu}m. Images collected from ex vivo, in vitro and in vivo samples using the device are also presented. The compact and cost-effective smartphone microendoscope may be envisaged as a powerful tool for detecting pre-cancerous lesions of internal organs in low and middle income countries.

  15. Quantitative analysis of cholesteatoma using high resolution computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Kikuchi, Shigeru; Yamasoba, Tatsuya (Kameda General Hospital, Chiba (Japan)); Iinuma, Toshitaka

    1992-05-01

    Seventy-three cases of adult cholesteatoma, including 52 cases of pars flaccida type cholesteatoma and 21 of pars tensa type cholesteatoma, were examined using high resolution computed tomography, in both axial (lateral semicircular canal plane) and coronal sections (cochlear, vestibular and antral plane). These cases were classified into two subtypes according to the presence of extension of cholesteatoma into the antrum. Sixty cases of chronic otitis media with central perforation (COM) were also examined as controls. Various locations of the middle ear cavity were measured in terms of size in comparison with pars flaccida type cholesteatoma, pars tensa type cholesteatoma and COM. The width of the attic was significantly larger in both pars flaccida type and pars tensa type cholesteatoma than in COM. With pars flaccida type cholesteatoma there was a significantly larger distance between the malleus and lateral wall of the attic than with COM. In contrast, the distance between the malleus and medial wall of the attic was significantly larger with pars tensa type cholesteatoma than with COM. With cholesteatoma extending into the antrum, regardless of the type of cholesteatoma, there were significantly larger distances than with COM at the following sites: the width and height of the aditus ad antrum, and the width, height and anterior-posterior diameter of the antrum. However, these distances were not significantly different between cholesteatoma without extension into the antrum and COM. The hitherto demonstrated qualitative impressions of bone destruction in cholesteatoma were quantitatively verified in detail using high resolution computed tomography. (author).

  16. The future of high resolution electron microscopy

    Institute of Scientific and Technical Information of China (English)

    D Van Dyck

    2000-01-01

    The state of the art and the future in quantitative high resolution electron microscopy are discussed in the framework of parameter estimation. Reconstruction methods are then to be considered as direct methods to yield a starting structure for further refinement. With the increasing flexibility of the instruments, computer aided experimental strategy will become important.

  17. High resolution spectroscopy of planet bearing stars

    Directory of Open Access Journals (Sweden)

    M. C. Gálvez

    2007-01-01

    Full Text Available We present here the first steps of an extended spectroscopic survey in order to characterize the stellar hosts of extra-solar planets. We have selected several known stars with plan- ets and using high resolution spectroscopy, we have studied their properties.

  18. High-resolution seismic profiling on water

    OpenAIRE

    McGee, T.M.

    2000-01-01

    Herein is presented an overview of high-resolution seismic profiling on water. Included are basic concepts and terminology as well as discussions of types of sources and receivers, field practice, data recording and data processing. Emphasis is on digital single-channel profiling for engineering and environmental purposes.

  19. Compact high-resolution spectral phase shaper

    NARCIS (Netherlands)

    Postma, S.; Walle, van der P.; Offerhaus, H.L.; Hulst, van N.F.

    2005-01-01

    The design and operation of a high-resolution spectral phase shaper with a footprint of only 7×10 cm2 is presented. The liquid-crystal modulator has 4096 elements. More than 600 independent degrees of freedom can be positioned with a relative accuracy of 1 pixel. The spectral shaping of pulses fro

  20. A High-Resolution Stopwatch for Cents

    Science.gov (United States)

    Gingl, Z.; Kopasz, K.

    2011-01-01

    A very low-cost, easy-to-make stopwatch is presented to support various experiments in mechanics. The high-resolution stopwatch is based on two photodetectors connected directly to the microphone input of a sound card. Dedicated free open-source software has been developed and made available to download. The efficiency is demonstrated by a free…

  1. Compressive sensing for high resolution radar imaging

    NARCIS (Netherlands)

    Anitori, L.; Otten, M.P.G.; Hoogeboom, P.

    2010-01-01

    In this paper we present some preliminary results on the application of Compressive Sensing (CS) to high resolution radar imaging. CS is a recently developed theory which allows reconstruction of sparse signals with a number of measurements much lower than what is required by the Shannon sampling th

  2. Concentration influences on recovery in a high gradient magnetic separation axial filter

    Energy Technology Data Exchange (ETDEWEB)

    Murariu, V.; Rezlescu, N.; Rotariu, O.; Badescu, V. [Inst. of Technical Physics, Iasi (Romania)

    1998-05-01

    The buildup differential equations for the case of a single wire in high gradient magnetic filtration (HGMF)-axial configuration taking into account the suspension concentration are solved. A new equation for the deposit contour surface at different moments and for different suspension concentrations are obtained. The existence of a particulate suspension concentration, for which the radial extension velocity of deposit is maximum, is evidenced. The recovery for an ordered ferromagnetic matrix is calculated. The influence of the solid particle concentration from suspension on the filtration efficiency is presented.

  3. Constructing a WISE High Resolution Galaxy Atlas

    Science.gov (United States)

    Jarrett, T. H.; Masci, F.; Tsai, C. W.; Petty, S.; Cluver, M.; Assef, Roberto J.; Benford, D.; Blain, A.; Bridge, C.; Donoso, E.; Eisenhardt, P.; Fowler, J.; Koribalski, B.; Lake, S.; Neill, James D.; Seibert, M.; Stanford, S.; Wright, E.

    2012-01-01

    After eight months of continuous observations, the Wide-field Infrared Survey Explorer (WISE) mapped the entire sky at 3.4 micron, 4.6 micron, 12 micron, and 22 micron. We have begun a dedicated WISE High Resolution Galaxy Atlas project to fully characterize large, nearby galaxies and produce a legacy image atlas and source catalog. Here we summarize the deconvolution techniques used to significantly improve the spatial resolution of WISE imaging, specifically designed to study the internal anatomy of nearby galaxies. As a case study, we present results for the galaxy NGC 1566, comparing the WISE enhanced-resolution image processing to that of Spitzer, Galaxy Evolution Explorer, and ground-based imaging. This is the first paper in a two-part series; results for a larger sample of nearby galaxies are presented in the second paper.

  4. High-resolution traction force microscopy.

    Science.gov (United States)

    Plotnikov, Sergey V; Sabass, Benedikt; Schwarz, Ulrich S; Waterman, Clare M

    2014-01-01

    Cellular forces generated by the actomyosin cytoskeleton and transmitted to the extracellular matrix (ECM) through discrete, integrin-based protein assemblies, that is, focal adhesions, are critical to developmental morphogenesis and tissue homeostasis, as well as disease progression in cancer. However, quantitative mapping of these forces has been difficult since there has been no experimental technique to visualize nanonewton forces at submicrometer spatial resolution. Here, we provide detailed protocols for measuring cellular forces exerted on two-dimensional elastic substrates with a high-resolution traction force microscopy (TFM) method. We describe fabrication of polyacrylamide substrates labeled with multiple colors of fiducial markers, functionalization of the substrates with ECM proteins, setting up the experiment, and imaging procedures. In addition, we provide the theoretical background of traction reconstruction and experimental considerations important to design a high-resolution TFM experiment. We describe the implementation of a new algorithm for processing of images of fiducial markers that are taken below the surface of the substrate, which significantly improves data quality. We demonstrate the application of the algorithm and explain how to choose a regularization parameter for suppression of the measurement error. A brief discussion of different ways to visualize and analyze the results serves to illustrate possible uses of high-resolution TFM in biomedical research. © 2014 Elsevier Inc. All rights reserved.

  5. High Resolution Real Time Sonography of the Thyroid Gland

    Directory of Open Access Journals (Sweden)

    A. Honarbakhsh

    2008-01-01

    Full Text Available Background/Objective: High-resolution sonography equipment permits for visualization of normal and abnormal thyroid gland with or without gel pad or water bath. This study prospectively presents surgically and pathologically proved patients with thyroid disease by direct ultrasound with or without Doppler (pulse, color, power Doppler."nPatients and Methods: This study was performed by 7.5-10 MHz frequency linear probe transducer with axial resolution of 0.7mm and lateral resolution of 1-2 mm (Aloka 650 and super SG 140 Toshiba unit assembly with color, power Doppler. Patient's neck was extended as a supine position."nResults: Pathologic proof was obtained in 45 patients with benign and five patients with malignant thyroid disease. Benign lesions were follicular adenoma in 30 patients, goiter in 10 patients, as hashimoto thyroiditis in two patients, hemorrhagic cyst in two patients and simple cyst in one patient. Malignant lesions were follicular, papillary, and medulary carcinoma which seen in two, two, and one patients respectively. Echopatterns were as follow: Most of them showed decreades echo when we compare to normal thyroid tissue, some malignant lesions showed increased echo and some isoecho, in the last group we need other work up for example Doppler (pulse, color, power for evaluation vascularity. We did not have metastasis to thyroid gland."nConclusion: With advace in technology in crystal and design overall probe as a result creat broadband width probe and also full digital sonography unit inclding (beam forming - CPU in images resolution is with high grade than semi digital unit that before used for thytoid gland. When With any reason resolution is increased we sould be able to diagnosed very small and smallest lesion (for example mest to thyroid or reccurency after total Lobectomy: there is three primay uses of sonography, 1 detection of mutionodular gland when only one nodule is suspected clinically and by isotop scan.2 High

  6. High resolution computed tomography for malformations of the cochlear and vestibular organs

    Energy Technology Data Exchange (ETDEWEB)

    Koester, O.; Straehler-Pohl, H.J.; Kim, K.H.

    1987-07-01

    Twenty-one patients with congenital deformities of the petrous bones were examined by high resolution computed tomography. This allows an accurate description of the extent of the malformation in all parts of the cochlear and vestibular organs; only localised changes in the auditory ossicles, such as fixation of the stapes and changes in the soft tissue portions of the labyrinth, cannot be shown. Improved demonstration of soft tissues while using less radiation makes high resolution CT preferable to conventional polytomography. It is also easier to perform and provides axial projections which are essential for the elucidation of malformations of the middle and inner ear.

  7. On the performance of circular concrete-filled high strength steel columns under axial loading

    Directory of Open Access Journals (Sweden)

    Mohamed Mahmoud El-Heweity

    2012-06-01

    Full Text Available This work presents a numerical study to investigate the performance of circular high-strength steel tubes filled with concrete (CFT under monotonic axial loading. A model is developed to implement the material constitutive relationships and non-linearity. Calibration against previous experimental data shows good agreement. A parametric study is then conducted using the model and compared with codes provisions. Strength and ductility of confined concrete are of primary concern. Variables considered are yield stress of steel tube and column diameter. The assessment of column performance is based on axial load carrying capacities and enhancements of both strength and ductility due to confinement. Two parameters namely strength enhancement factor (Kf and ductility index (μ are clearly defined and introduced for assessment. Results indicate that both concrete strength and ductility of CFT columns are enhanced but to different extents. The ductile behaviors are significantly evident. The increase in yield stress of steel tube has a minimal effect on concrete strength but pronounced effect on concrete ductility. However, reduction in ductility is associated with using high-tensile steel of Grade 70. The overall findings indicate that the use of high-strength tube in CFT columns is not promising. This finding may seriously be considered in seismic design.

  8. Development of a high resolution and high dispersion Thomson parabola.

    Science.gov (United States)

    Jung, D; Hörlein, R; Kiefer, D; Letzring, S; Gautier, D C; Schramm, U; Hübsch, C; Öhm, R; Albright, B J; Fernandez, J C; Habs, D; Hegelich, B M

    2011-01-01

    Here, we report on the development of a novel high resolution and high dispersion Thomson parabola for simultaneously resolving protons and low-Z ions of more than 100 MeV/nucleon necessary to explore novel laser ion acceleration schemes. High electric and magnetic fields enable energy resolutions of ΔE∕E parabola for ion energies of more than 30 MeV/nucleon.

  9. A dedicated high resolution PET imager for plant sciences

    CERN Document Server

    Wang, Qiang; Li, Ke; Wen, Jie; Komarov, Sergey; O'Sullivan, Joseph A; Tai, Yuan-Chuan

    2014-01-01

    PET provides in vivo molecular and functional imaging capability that is crucial to studying the interaction of plant with changing environment at the whole-plant level. We have developed a dedicated plant PET imager that features high spatial resolution, housed in a fully controlled environment provided by a plant growth chamber (PGC). The system currently contains two types of detector modules: 84 microPET R4 block detectors with 2.2 mm crystals to provide a large detecting area; and 32 Inveon block detectors with 1.5 mm crystals to provide higher spatial resolution. Outputs of the four microPET block detectors in a modular housing are concatenated by a custom printed circuit board to match the output characteristics of an Inveon detector. All the detectors are read out by QuickSilver electronics. The detector modules are configured to full rings with a 15 cm diameter trans-axial field of view (FOV) for dynamic tomographic imaging of small plants. Potentially, the Inveon detectors can be reconfigured to qua...

  10. High resolution 3D nonlinear integrated inversion

    Institute of Scientific and Technical Information of China (English)

    Li Yong; Wang Xuben; Li Zhirong; Li Qiong; Li Zhengwen

    2009-01-01

    The high resolution 3D nonlinear integrated inversion method is based on nonlinear theory. Under layer control, the log data from several wells (or all wells) in the study area and seismic trace data adjacent to the wells are input to a network with multiple inputs and outputs and are integratedly trained to obtain an adaptive weight function of the entire study area. Integrated nonlinear mapping relationships are built and updated by the lateral and vertical geologic variations of the reservoirs. Therefore, the inversion process and its inversion results can be constrained and controlled and a stable seismic inversion section with high resolution with velocity inversion, impedance inversion, and density inversion sections, can be gained. Good geologic effects have been obtained in model computation tests and real data processing, which verified that this method has high precision, good practicality, and can be used for quantitative reservoir analysis.

  11. Progress toward high resolution EUV spectroscopy

    Science.gov (United States)

    Korendyke, C.; Doschek, G. A.; Warren, H.; Young, P. R.; Chua, D.; Hassler, D. M.; Landi, E.; Davila, J. M.; Klimchuck, J.; Tun, S.; DeForest, C.; Mariska, J. T.; Solar C Spectroscopy Working Group; LEMUR; EUVST Development Team

    2013-07-01

    HIgh resolution EUV spectroscopy is a critical instrumental technique to understand fundamental physical processes in the high temperature solar atmosphere. Spectroscopic observations are used to measure differential emission measure, line of sight and turbulent flows, plasma densities and emission measures. Spatially resolved, spectra of these emission lines with adequate cadence will provide the necessary clues linking small scale structures with large scale, energetic solar phenomena. The necessary observations to determine underlying physical processes and to provide comprehensive temperature coverage of the solar atmosphere above the chromosphere will be obtained by the proposed EUVST instrument for Solar C. This instrument and its design will be discussed in this paper. Progress on the VEry high Resolution Imaging Spectrograph (VERIS) sounding rocket instrument presently under development at the Naval Research Laboratory will also be discussed.

  12. Superconducting High Resolution Fast-Neutron Spectrometers

    Energy Technology Data Exchange (ETDEWEB)

    Hau, Ionel Dragos [Univ. of California, Berkeley, CA (United States)

    2006-01-01

    Superconducting high resolution fast-neutron calorimetric spectrometers based on 6LiF and TiB{sub 2} absorbers have been developed. These novel cryogenic spectrometers measure the temperature rise produced in exothermal (n, α) reactions with fast neutrons in 6Li and 10B-loaded materials with heat capacity C operating at temperatures T close to 0.1 K. Temperature variations on the order of 0.5 mK are measured with a Mo/Cu thin film multilayer operated in the transition region between its superconducting and its normal state. The advantage of calorimetry for high resolution spectroscopy is due to the small phonon excitation energies kBT on the order of μeV that serve as signal carriers, resulting in an energy resolution ΔE ~ (kBT2C)1/2, which can be well below 10 keV. An energy resolution of 5.5 keV has been obtained with a Mo/Cu superconducting sensor and a TiB2 absorber using thermal neutrons from a 252Cf neutron source. This resolution is sufficient to observe the effect of recoil nuclei broadening in neutron spectra, which has been related to the lifetime of the first excited state in 7Li. Fast-neutron spectra obtained with a 6Li-enriched LiF absorber show an energy resolution of 16 keV FWHM, and a response in agreement with the 6Li(n, α)3H reaction cross section and Monte Carlo simulations for energies up to several MeV. The energy resolution of order of a few keV makes this novel instrument applicable to fast-neutron transmission spectroscopy based on the unique elemental signature provided by the neutron absorption and scattering resonances. The optimization of the energy resolution based on analytical and numerical models of the detector response is discussed in the context of these applications.

  13. Low-pressure reversible axial fan with straight profile blades and relatively high efficiency

    Directory of Open Access Journals (Sweden)

    Spasić Živan T.

    2012-01-01

    Full Text Available The paper presents the design and operating characteristics of a model of reversible axial fan with only one impeller, whose reversibility is achieved by changing the direction of rotation. The fan is designed for the purpose of providing alternating air circulation in wood dryers in order to reduce the consumption of electricity for the fan and increase energy efficiency of the entire dryer. To satisfy the reversibility of flow, the shape of the blade profile is symmetrical along the longitudinal and transversal axes of the profile. The fan is designed with equal specific work of all elementary stages, using the method of lift forces. The impeller blades have straight mean line profiles. The shape of the blade profile was adopted after the numerical simulations were carried out and high efficiency was achieved. Based on the calculation and conducted numerical simulations, a physical model of the fan was created and tested on a standard test rig, with air loading at the suction side of the fan. The operating characteristics are shown for different blade angles. The obtained maximum efficiency was around 0.65, which represents a rather high value for axial fans with straight profile blades.

  14. High-Resolution US of Rheumatologic Diseases.

    Science.gov (United States)

    Taljanovic, Mihra S; Melville, David M; Gimber, Lana H; Scalcione, Luke R; Miller, Margaret D; Kwoh, C Kent; Klauser, Andrea S

    2015-01-01

    For the past 15 years, high-resolution ultrasonography (US) is being routinely and increasingly used for initial evaluation and treatment follow-up of rheumatologic diseases. This imaging technique is performed by using high-frequency linear transducers and has proved to be a powerful diagnostic tool in evaluation of articular erosions, simple and complex joint and bursal effusions, tendon sheath effusions, and synovitis, with results comparable to those of magnetic resonance imaging, excluding detection of bone marrow edema. Crystal deposition diseases including gouty arthropathy and calcium pyrophosphate deposition disease (CPPD) have characteristic appearances at US, enabling differentiation between these two diseases and from inflammatory arthropathies. Enthesopathy, which frequently accompanies psoriatic and reactive arthritis, also has a characteristic appearance at high-resolution US, distinguishing these two entities from other inflammatory and metabolic arthropathies. The presence of Doppler signal in examined joints, bursae, and tendon sheaths indicates active synovitis. Microbubble echo contrast agents augment detection of tissue vascularity and may act in the future as a drug delivery vehicle. Frequently, joint, tendon sheath, and bursal fluid aspirations and therapeutic injections are performed under US guidance. The authors describe the high-resolution US technique including gray-scale, color or power Doppler, and contrast agent-enhanced US that is used in evaluation of rheumatologic diseases of the wrist and hand and the ankle and foot in their routine clinical practice. This article demonstrates imaging findings of normal joints, rheumatoid arthritis, gouty arthritis, CPPD, psoriatic and reactive arthritis, and osteoarthritis.

  15. High-resolution flurescence spectroscopy in immunoanalysis

    Energy Technology Data Exchange (ETDEWEB)

    Grubor, Nenad M.

    2005-05-01

    The work presented in this dissertation combines highly sensitive and selective fluorescence line-narrowing spectroscopy (FLNS) detection with various modes of immunoanalytical techniques. It has been shown that FLNS is capable of directly probing molecules immunocomplexed with antibodies, eliminating analytical ambiguities that may arise from interferences that accompany traditional immunochemical techniques. Moreover, the utilization of highly cross-reactive antibodies for highly specific analyte determination has been demonstrated. Finally, they demonstrate the first example of the spectral resolution of diastereomeric analytes based on their interaction with a cross-reactive antibody.

  16. High-resolution flurescence spectroscopy in immunoanalysis

    Energy Technology Data Exchange (ETDEWEB)

    Grubor, Nenad M. [Iowa State Univ., Ames, IA (United States)

    2005-01-01

    The work presented in this dissertation combines highly sensitive and selective fluorescence line-narrowing spectroscopy (FLNS) detection with various modes of immunoanalytical techniques. It has been shown that FLNS is capable of directly probing molecules immunocomplexed with antibodies, eliminating analytical ambiguities that may arise from interferences that accompany traditional immunochemical techniques. Moreover, the utilization of highly cross-reactive antibodies for highly specific analyte determination has been demonstrated. Finally, they demonstrate the first example of the spectral resolution of diastereomeric analytes based on their interaction with a cross-reactive antibody.

  17. High-resolution TOF with RPCs

    Energy Technology Data Exchange (ETDEWEB)

    Fonte, P. E-mail: fonte@lipc.fis.uc.pt; Peskov, V

    2002-01-21

    In this work, we describe some recent results concerning the application of Resistive Plate Chambers operated in avalanche mode at atmospheric pressure for high-resolution time-of-flight measurements. A combination of multiple, mechanically accurate, thin gas gaps and state-of-the-art electronics yielded an overall (detector plus electronics) timing accuracy better than 50 ps {sigma} with a detection efficiency up to 99% for MIPs. Single gap chambers were also tested in order to clarify experimentally several aspects of the mode of operation of these detectors. These results open perspectives of affordable and reliable high granularity large area TOF detectors, with an efficiency and time resolution comparable to the existing scintillator-based TOF technology but with a significantly, up to an order of magnitude, lower price per channel.

  18. Structural High-resolution Satellite Image Indexing

    OpenAIRE

    Xia, Gui-Song; YANG, WEN; Delon, Julie; Gousseau, Yann; Sun, Hong; Maître, Henri

    2010-01-01

    International audience; Satellite images with high spatial resolution raise many challenging issues in image understanding and pattern recognition. First, they allow measurement of small objects maybe up to 0.5 m, and both texture and geometrical structures emerge simultaneously. Second, objects in the same type of scenes might appear at different scales and orientations. Consequently, image indexing methods should combine the structure and texture information of images and comply with some i...

  19. Stellar Tools for High Resolution Population Synthesis

    Science.gov (United States)

    Chávez, M.; Bertone, E.; Rodríguez-Merino, L.; Buzzoni, A.

    2005-12-01

    We present preliminary results of the application of a new stellar library of high-resolution synthetic spectra (based upon ATLAS9 and SYNTHE codes developed by R. L. Kurucz) in the calculation of the ultraviolet-optical spectral energy distribution of simple stellar populations (SSPs). For this purpose, the library has been coupled with Buzzoni's population synthesis code. Part of this paper is also devoted to illustrate quantitatively the extent to which synthetic stellar libraries represent real stars.

  20. Petrous apex mucocele: high resolution CT

    Energy Technology Data Exchange (ETDEWEB)

    Memis, A. [Dept. of Radiology, Hospital of Ege Univ., Bornova, Izmir (Turkey); Memis, A. [Dept. of Radiology, Hospital of Ege Univ., Bornova, Izmir (Turkey); Alper, H. [Dept. of Radiology, Hospital of Ege Univ., Bornova, Izmir (Turkey); Calli, C. [Dept. of Radiology, Hospital of Ege Univ., Bornova, Izmir (Turkey); Ozer, H. [Dept. of Radiology, Hospital of Ege Univ., Bornova, Izmir (Turkey); Ozdamar, N. [Dept. of Neurosurgery, Hospital of Ege Univ., Bornova, Izmir (Turkey)

    1994-11-01

    Mucocele of the petrous apex is very rare, only three cases having been reported. Since this area is inaccessible to direct examination, imaging, preferably high resolution computed tomography (HR CT) is essential. We report a case showing an eroding, non enhancing mass with sharp, lobulated contours, within the petrous apex. The presence of a large air cell on the opposite side suggested a mucocele. (orig.)

  1. High resolution NMR theory and chemical applications

    CERN Document Server

    Becker, Edwin D

    1969-01-01

    High Resolution NMR: Theory and Chemical Applications focuses on the applications of nuclear magnetic resonance (NMR), as well as chemical shifts, lattices, and couplings. The book first offers information on the theory of NMR, including nuclear spin and magnetic moment, spin lattice relaxation, line widths, saturation, quantum mechanical description of NMR, and ringing. The text then ponders on instrumentation and techniques and chemical shifts. Discussions focus on the origin of chemical shifts, reference compounds, empirical correlations of chemical shifts, modulation and phase detection,

  2. High Speed and High Resolution Table-Top Nanoscale Imaging

    CERN Document Server

    Tadesse, G K; Demmler, S; HÄdrich, S; Wahyutama, I; Steinert, M; Spielmann, C; ZÜrch, M; TÜnnermann, A; Limpert, J; Rothhardt, J

    2016-01-01

    We present a table-top coherent diffraction imaging (CDI) experiment based on high-order harmonics generated at 18 nm by a high average power femtosecond fiber laser system. The high photon flux, narrow spectral bandwidth and high degree of spatial coherence allow for ultra-high sub-wavelength resolution imaging at a high numerical aperture. Our experiments demonstrate a half-pitch resolution of 13.6 nm, very close to the actual Abbe-limit of 12.4 nm, which is the highest resolution achieved from any table-top XUV or X-ray microscope. In addition, 20.5 nm resolution was achieved with only 3 sec of integration time bringing live diffraction imaging and 3D tomography on the nanoscale one step closer to reality. The current resolution is solely limited by the wavelength and the detector size. Thus, table-top nanoscopes with only a few-nm resolutions are in reach and will find applications in many areas of science and technology.

  3. High Sensitivity, High Frequency and High Time Resolution Decimetric Spectroscope

    Science.gov (United States)

    Sawant, H. S.; Rosa, R. R.

    1990-11-01

    RESUMEN. Se ha desarrollado el primer espectroscopio decimetrico latino americano operando en una banda de 100 MHz con alta resoluci6n de fre- cuencia (100 KHz) y tiempo (10 ms), alrededor de cualquier centro de frecuencia en el intervalo de 2000-200 MHz. El prop6sito de esta nota es describir investigaciones solares y no solares que se planean, progra ma de investigaci6n y la situaci6n actual de desarrollo de este espectroscopio. ABSTRACT. First Latin American Decimetric Spectroscope operating over a band of 100 MHz with high resolution in frequency (100 KHz) and time (10 ms), around any center frequency in the range of 2000-200 MHz is being developed. The purpose of this note is to describe planned solar, and non-solar, research programmes and present status of development of this spectroscope. Keq wo : INSTRUMENTS - SPECTROSCOPY

  4. High Resolution Measurement of the Glycolytic Rate

    Science.gov (United States)

    Bittner, Carla X.; Loaiza, Anitsi; Ruminot, Iván; Larenas, Valeria; Sotelo-Hitschfeld, Tamara; Gutiérrez, Robin; Córdova, Alex; Valdebenito, Rocío; Frommer, Wolf B.; Barros, L. Felipe

    2010-01-01

    The glycolytic rate is sensitive to physiological activity, hormones, stress, aging, and malignant transformation. Standard techniques to measure the glycolytic rate are based on radioactive isotopes, are not able to resolve single cells and have poor temporal resolution, limitations that hamper the study of energy metabolism in the brain and other organs. A new method is described in this article, which makes use of a recently developed FRET glucose nanosensor to measure the rate of glycolysis in single cells with high temporal resolution. Used in cultured astrocytes, the method showed for the first time that glycolysis can be activated within seconds by a combination of glutamate and K+, supporting a role for astrocytes in neurometabolic and neurovascular coupling in the brain. It was also possible to make a direct comparison of metabolism in neurons and astrocytes lying in close proximity, paving the way to a high-resolution characterization of brain energy metabolism. Single-cell glycolytic rates were also measured in fibroblasts, adipocytes, myoblasts, and tumor cells, showing higher rates for undifferentiated cells and significant metabolic heterogeneity within cell types. This method should facilitate the investigation of tissue metabolism at the single-cell level and is readily adaptable for high-throughput analysis. PMID:20890447

  5. High resolution measurement of the glycolytic rate

    Directory of Open Access Journals (Sweden)

    Carla X Bittner

    2010-09-01

    Full Text Available The glycolytic rate is sensitive to physiological activity, hormones, stress, aging and malignant transformation. Standard techniques to measure the glycolytic rate are based on radioactive isotopes, are not able to resolve single cells and have poor temporal resolution, limitations that hamper the study of energy metabolism in the brain and other organs. A new method is described in this article, which makes use of a recently-developed FRET glucose nanosensor to measure the rate of glycolysis in single cells with high temporal resolution. Used in cultured astrocytes, the method showed for the first time that glycolysis can be activated within seconds by a combination of glutamate and K+, supporting a role for astrocytes in neurometabolic and neurovascular coupling in the brain. It was also possible to make a direct comparison of metabolism in neurons and astrocytes lying in close proximity, paving the way to a high-resolution characterization of brain energy metabolism. Single-cell glycolytic rates were also measured in fibroblasts, adipocytes, myoblasts and tumor cells, showing higher rates for undifferentiated cells and significant metabolic heterogeneity within cell types. This method should facilitate the investigation of tissue metabolism at the single-cell level and is readily adaptable for high-throughput analysis.

  6. Performance evaluation of a high resolution dedicated breast PET scanner

    Energy Technology Data Exchange (ETDEWEB)

    García Hernández, Trinitat, E-mail: mtrinitat@eresa.com; Vicedo González, Aurora; Brualla González, Luis; Granero Cabañero, Domingo [Department of Medical Physics, ERESA, Hospital General Universitario, Valencia 46014 (Spain); Ferrer Rebolleda, Jose; Sánchez Jurado, Raúl; Puig Cozar Santiago, Maria del [Department of Nuclear Medicine, ERESA, Hospital General Universitario, Valencia 46014 (Spain); Roselló Ferrando, Joan [Department of Medical Physics, ERESA, Hospital General Universitario, Valencia 46014 (Spain); Department of Physiology, University of Valencia, Valencia 46010 (Spain)

    2016-05-15

    Purpose: Early stage breast cancers may not be visible on a whole-body PET scan. To overcome whole-body PET limitations, several dedicated breast positron emission tomography (DbPET) systems have emerged nowadays aiming to improve spatial resolution. In this work the authors evaluate the performance of a high resolution dedicated breast PET scanner (Mammi-PET, Oncovision). Methods: Global status, uniformity, sensitivity, energy, and spatial resolution were measured. Spheres of different sizes (2.5, 4, 5, and 6 mm diameter) and various 18 fluorodeoxyglucose ({sup 18}F-FDG) activity concentrations were randomly inserted in a gelatine breast phantom developed at our institution. Several lesion-to-background ratios (LBR) were simulated, 5:1, 10:1, 20:1, 30:1, and 50:1. Images were reconstructed using different voxel sizes. The ability of experienced reporters to detect spheres was tested as a function of acquisition time, LBR, sphere size, and matrix reconstruction voxel size. For comparison, phantoms were scanned in the DbPET camera and in a whole body PET (WB-PET). Two patients who just underwent WB-PET/CT exams were imaged with the DbPET system and the images were compared. Results: The measured absolute peak sensitivity was 2.0%. The energy resolution was 24.0% ± 1%. The integral and differential uniformity were 10% and 6% in the total field of view (FOV) and 9% and 5% in the central FOV, respectively. The measured spatial resolution was 2.0, 1.9, and 1.7 mm in the radial, tangential, and axial directions. The system exhibited very good detectability for spheres ≥4 mm and LBR ≥10 with a sphere detection of 100% when acquisition time was set >3 min/bed. For LBR = 5 and acquisition time of 7 min the detectability was 100% for spheres of 6 mm and 75% for spheres of 5, 4, and 2.5 mm. Lesion WB-PET detectability was only comparable to the DbPET camera for lesion sizes ≥5 mm when acquisition time was >3 min and LBR > 10. Conclusions: The DbPET has a good

  7. A Combined Multiple-SLED Broadband Light Source at 1300 nm for High Resolution Optical Coherence Tomography.

    Science.gov (United States)

    Wang, Hui; Jenkins, Michael W; Rollins, Andrew M

    2008-04-01

    We demonstrate a compact, inexpensive, and reliable fiber-coupled light source with broad bandwidth and sufficient power at 1300 nm for high resolution optical coherence tomography (OCT) imaging in real-time applications. By combining four superluminescent diodes (SLEDs) with different central wavelengths, the light source has a bandwidth of 145 nm centered at 1325 nm with over 10 mW of power. OCT images of an excised stage 30 embryonic chick heart acquired with our combined SLED light source (<5 μm axial resolution in tissue) are compared with images obtained with a single SLED source (~10 μm axial resolution in tissue). The high resolution OCT system with the combined SLED light source provides better image quality (smaller speckle noise) and a greater ability to observe fine structures in the embryonic heart.

  8. A Combined Multiple-SLED Broadband Light Source at 1300 nm for High Resolution Optical Coherence Tomography

    Science.gov (United States)

    Wang, Hui; Jenkins, Michael W.; Rollins, Andrew M.

    2013-01-01

    We demonstrate a compact, inexpensive, and reliable fiber–coupled light source with broad bandwidth and sufficient power at 1300 nm for high resolution optical coherence tomography (OCT) imaging in real-time applications. By combining four superluminescent diodes (SLEDs) with different central wavelengths, the light source has a bandwidth of 145 nm centered at 1325 nm with over 10 mW of power. OCT images of an excised stage 30 embryonic chick heart acquired with our combined SLED light source (<5 μm axial resolution in tissue) are compared with images obtained with a single SLED source (~10 μm axial resolution in tissue). The high resolution OCT system with the combined SLED light source provides better image quality (smaller speckle noise) and a greater ability to observe fine structures in the embryonic heart. PMID:24347689

  9. SPIRAL2/DESIR high resolution mass separator

    Energy Technology Data Exchange (ETDEWEB)

    Kurtukian-Nieto, T., E-mail: kurtukia@cenbg.in2p3.fr [Centre d’Études Nucléaires de Bordeaux Gradignan, Université Bordeaux 1-CNRS/IN2P3, BP 120, F-33175 Gradignan Cedex (France); Baartman, R. [TRIUMF, 4004 Wesbrook Mall, Vancouver B.C., V6T 2A3 (Canada); Blank, B.; Chiron, T. [Centre d’Études Nucléaires de Bordeaux Gradignan, Université Bordeaux 1-CNRS/IN2P3, BP 120, F-33175 Gradignan Cedex (France); Davids, C. [Physics Division, Argonne National Laboratory, Argonne, IL 60439 (United States); Delalee, F. [Centre d’Études Nucléaires de Bordeaux Gradignan, Université Bordeaux 1-CNRS/IN2P3, BP 120, F-33175 Gradignan Cedex (France); Duval, M. [GANIL, CEA/DSM-CNRS/IN2P3, Bd Henri Becquerel, BP 55027, F-14076 Caen Cedex 5 (France); El Abbeir, S.; Fournier, A. [Centre d’Études Nucléaires de Bordeaux Gradignan, Université Bordeaux 1-CNRS/IN2P3, BP 120, F-33175 Gradignan Cedex (France); Lunney, D. [CSNSM-IN2P3-CNRS, Université de Paris Sud, F-91405 Orsay (France); Méot, F. [BNL, Upton, Long Island, New York (United States); Serani, L. [Centre d’Études Nucléaires de Bordeaux Gradignan, Université Bordeaux 1-CNRS/IN2P3, BP 120, F-33175 Gradignan Cedex (France); Stodel, M.-H.; Varenne, F. [GANIL, CEA/DSM-CNRS/IN2P3, Bd Henri Becquerel, BP 55027, F-14076 Caen Cedex 5 (France); and others

    2013-12-15

    DESIR is the low-energy part of the SPIRAL2 ISOL facility under construction at GANIL. DESIR includes a high-resolution mass separator (HRS) with a designed resolving power m/Δm of 31,000 for a 1 π-mm-mrad beam emittance, obtained using a high-intensity beam cooling device. The proposed design consists of two 90-degree magnetic dipoles, complemented by electrostatic quadrupoles, sextupoles, and a multipole, arranged in a symmetric configuration to minimize aberrations. A detailed description of the design and results of extensive simulations are given.

  10. Moderate resolution spectrophotometry of high redshift quasars

    Science.gov (United States)

    Schneider, Donald P.; Schmidt, Maarten; Gunn, James E.

    1991-01-01

    A uniform set of photometry and high signal-to-noise moderate resolution spectroscopy of 33 quasars with redshifts larger than 3.1 is presented. The sample consists of 17 newly discovered quasars (two with redshifts in excess of 4.4) and 16 sources drawn from the literature. The objects in this sample have r magnitudes between 17.4 and 21.4; their luminosities range from -28.8 to -24.9. Three of the 33 objects are broad absorption line quasars. A number of possible high redshift damped Ly-alpha systems were found.

  11. Radiation length imaging with high resolution telescopes

    CERN Document Server

    Stolzenberg, U; Schwenker, B; Wieduwilt, P; Marinas, C; Lütticke, F

    2016-01-01

    The construction of low mass vertex detectors with a high level of system integration is of great interest for next generation collider experiments. Radiation length images with a sufficient spatial resolution can be used to measure and disentangle complex radiation length $X$/$X_0$ profiles and contribute to the understanding of vertex detector systems. Test beam experiments with multi GeV particle beams and high-resolution tracking telescopes provide an opportunity to obtain precise 2D images of the radiation length of thin planar objects. At the heart of the $X$/$X_0$ imaging is a spatially resolved measurement of the scattering angles of particles traversing the object under study. The main challenges are the alignment of the reference telescope and the calibration of its angular resolution. In order to demonstrate the capabilities of $X$/$X_0$ imaging, a test beam experiment has been conducted. The devices under test were two mechanical prototype modules of the Belle II vertex detector. A data sample of ...

  12. High Resolution Bathymetry Estimation Improvement with Single ImageSuper Resolution Algorithm Super Resolution Forests

    Science.gov (United States)

    2017-01-26

    process of the SRF algorithm, we were able to further increase the mean PSNR score of the high resolution estimated data from previously used bicubic...This meant that implementing the edited variance before the bicubic estimates were created caused the mean PSNR to increase the most, and all...interpolation (by about 1 dB). Figure 7: PSNR comparison (with mean scores) between Bicubic Interpolation and SRF Figure 7 shows the comparison between

  13. High-time Resolution Astrophysics and Pulsars

    CERN Document Server

    Shearer, Andy

    2008-01-01

    The discovery of pulsars in 1968 heralded an era where the temporal characteristics of detectors had to be reassessed. Up to this point detector integration times would normally be measured in minutes rather seconds and definitely not on sub-second time scales. At the start of the 21st century pulsar observations are still pushing the limits of detector telescope capabilities. Flux variations on times scales less than 1 nsec have been observed during giant radio pulses. Pulsar studies over the next 10 to 20 years will require instruments with time resolutions down to microseconds and below, high-quantum quantum efficiency, reasonable energy resolution and sensitive to circular and linear polarisation of stochastic signals. This chapter is review of temporally resolved optical observations of pulsars. It concludes with estimates of the observability of pulsars with both existing telescopes and into the ELT era.

  14. Novel high-resolution VGA QWIP detector

    Science.gov (United States)

    Kataria, H.; Asplund, C.; Lindberg, A.; Smuk, S.; Alverbro, J.; Evans, D.; Sehlin, S.; Becanovic, S.; Tinghag, P.; Höglund, L.; Sjöström, F.; Costard, E.

    2017-02-01

    Continuing with its legacy of producing high performance infrared detectors, IRnova introduces its high resolution LWIR IDDCA (Integrated Detector Dewar Cooler assembly) based on QWIP (quantum well infrared photodetector) technology. The Focal Plane Array (FPA) has 640×512 pixels, with small (15μm) pixel pitch, and is based on the FLIRIndigo ISC0403 Readout Integrated Circuit (ROIC). The QWIP epitaxial structures are grown by metal-organic vapor phase epitaxy (MOVPE) at IRnova. Detector stability and response uniformity inherent to III/V based material will be demonstrated in terms of high performing detectors. Results showing low NETD at high frame rate will be presented. This makes it one of the first 15μm pitch QWIP based LWIR IDDCA commercially available on the market. High operability and stability of our other QWIP based products will also be shared.

  15. High-Temporal-Resolution High-Spatial-Resolution Spaceborne SAR Based on Continuously Varying PRF.

    Science.gov (United States)

    Men, Zhirong; Wang, Pengbo; Li, Chunsheng; Chen, Jie; Liu, Wei; Fang, Yue

    2017-07-25

    Synthetic Aperture Radar (SAR) is a well-established and powerful imaging technique for acquiring high-spatial-resolution images of the Earth's surface. With the development of beam steering techniques, sliding spotlight and staring spotlight modes have been employed to support high-spatial-resolution applications. In addition to this strengthened high-spatial-resolution and wide-swath capability, high-temporal-resolution (short repeat-observation interval) represents a key capability for numerous applications. However, conventional SAR systems are limited in that the same patch can only be illuminated for several seconds within a single pass. This paper considers a novel high-squint-angle system intended to acquire high-spatial-resolution spaceborne SAR images with repeat-observation intervals varying from tens of seconds to several minutes within a single pass. However, an exponentially increased range cell migration would arise and lead to a conflict between the receive window and 'blind ranges'. An efficient data acquisition technique for high-temporal-resolution, high-spatial-resolution and high-squint-angle spaceborne SAR, in which the pulse repetition frequency (PRF) is continuously varied according to the changing slant range, is presented in this paper. This technique allows echo data to remain in the receive window instead of conflicting with the transmitted pulse or nadir echo. Considering the precision of hardware, a compromise and practical strategy is also proposed. Furthermore, a detailed performance analysis of range ambiguities is provided with respect to parameters of TerraSAR-X. For strong point-like targets, the range ambiguity of this technique would be better than that of uniform PRF technique. For this innovative technique, a resampling strategy and modified imaging algorithm have been developed to handle the non-uniformly sampled echo data. Simulations are performed to validate the efficiency of the proposed technique and the associated

  16. Performance of a highly loaded two stage axial-flow fan

    Science.gov (United States)

    Ruggeri, R. S.; Benser, W. A.

    1974-01-01

    A two-stage axial-flow fan with a tip speed of 1450 ft/sec (442 m/sec) and an overall pressure ratio of 2.8 was designed, built, and tested. At design speed and pressure ratio, the measured flow matched the design value of 184.2 lbm/sec (83.55kg/sec). The adiabatic efficiency at the design operating point was 85.7 percent. The stall margin at design speed was 10 percent. A first-bending-mode flutter of the second-stage rotor blades was encountered near stall at speeds between 77 and 93 percent of design, and also at high pressure ratios at speeds above 105 percent of design. A 5 deg closed reset of the first-stage stator eliminated second-stage flutter for all but a narrow speed range near 90 percent of design.

  17. Integrated High Resolution Monitoring of Mediterranean vegetation

    Science.gov (United States)

    Cesaraccio, Carla; Piga, Alessandra; Ventura, Andrea; Arca, Angelo; Duce, Pierpaolo; Mereu, Simone

    2017-04-01

    The study of the vegetation features in a complex and highly vulnerable ecosystems, such as Mediterranean maquis, leads to the need of using continuous monitoring systems at high spatial and temporal resolution, for a better interpretation of the mechanisms of phenological and eco-physiological processes. Near-surface remote sensing techniques are used to quantify, at high temporal resolution, and with a certain degree of spatial integration, the seasonal variations of the surface optical and radiometric properties. In recent decades, the design and implementation of global monitoring networks involved the use of non-destructive and/or cheaper approaches such as (i) continuous surface fluxes measurement stations, (ii) phenological observation networks, and (iii) measurement of temporal and spatial variations of the vegetation spectral properties. In this work preliminary results from the ECO-SCALE (Integrated High Resolution Monitoring of Mediterranean vegetation) project are reported. The project was manly aimed to develop an integrated system for environmental monitoring based on digital photography, hyperspectral radiometry , and micrometeorological techniques during three years of experimentation (2013-2016) in a Mediterranean site of Italy (Capo Caccia, Alghero). The main results concerned the analysis of chromatic coordinates indices from digital images, to characterized the phenological patterns for typical shrubland species, determining start and duration of the growing season, and the physiological status in relation to different environmental drought conditions; then the seasonal patterns of canopy phenology, was compared to NEE (Net Ecosystem Exchange) patterns, showing similarities. However, maximum values of NEE and ER (Ecosystem respiration), and short term variation, seemed mainly tuned by inter annual pattern of meteorological variables, in particular of temperature recorded in the months preceding the vegetation green-up. Finally, green signals

  18. High-resolution phylogenetic microbial community profiling

    Energy Technology Data Exchange (ETDEWEB)

    Singer, Esther; Coleman-Derr, Devin; Bowman, Brett; Schwientek, Patrick; Clum, Alicia; Copeland, Alex; Ciobanu, Doina; Cheng, Jan-Fang; Gies, Esther; Hallam, Steve; Tringe, Susannah; Woyke, Tanja

    2014-03-17

    The representation of bacterial and archaeal genome sequences is strongly biased towards cultivated organisms, which belong to merely four phylogenetic groups. Functional information and inter-phylum level relationships are still largely underexplored for candidate phyla, which are often referred to as microbial dark matter. Furthermore, a large portion of the 16S rRNA gene records in the GenBank database are labeled as environmental samples and unclassified, which is in part due to low read accuracy, potential chimeric sequences produced during PCR amplifications and the low resolution of short amplicons. In order to improve the phylogenetic classification of novel species and advance our knowledge of the ecosystem function of uncultivated microorganisms, high-throughput full length 16S rRNA gene sequencing methodologies with reduced biases are needed. We evaluated the performance of PacBio single-molecule real-time (SMRT) sequencing in high-resolution phylogenetic microbial community profiling. For this purpose, we compared PacBio and Illumina metagenomic shotgun and 16S rRNA gene sequencing of a mock community as well as of an environmental sample from Sakinaw Lake, British Columbia. Sakinaw Lake is known to contain a large age of microbial species from candidate phyla. Sequencing results show that community structure based on PacBio shotgun and 16S rRNA gene sequences is highly similar in both the mock and the environmental communities. Resolution power and community representation accuracy from SMRT sequencing data appeared to be independent of GC content of microbial genomes and was higher when compared to Illumina-based metagenome shotgun and 16S rRNA gene (iTag) sequences, e.g. full-length sequencing resolved all 23 OTUs in the mock community, while iTags did not resolve closely related species. SMRT sequencing hence offers various potential benefits when characterizing uncharted microbial communities.

  19. Novel high resolution tactile robotic fingertips

    DEFF Research Database (Denmark)

    Drimus, Alin; Jankovics, Vince; Gorsic, Matija

    2014-01-01

    This paper describes a novel robotic fingertip based on piezoresistive rubber that can sense pressure tactile stimuli with a high spatial resolution over curved surfaces. The working principle is based on a three-layer sandwich structure (conductive electrodes on top and bottom and piezoresistive...... with specialized data acquisition electronics that acquire 500 frames per second provides rich information regarding contact force, shape and angle for bio- inspired robotic fingertips. Furthermore, a model of estimating the force of contact based on values of the cells is proposed....

  20. Fast Backprojection Techniques for High Resolution Tomography

    CERN Document Server

    Koshev, Nikolay; Miqueles, Eduardo X

    2016-01-01

    Fast image reconstruction techniques are becoming important with the increasing number of scientific cases in high resolution micro and nano tomography. The processing of the large scale three-dimensional data demands new mathematical tools for the tomographic reconstruction task because of the big computational complexity of most current algorithms as the sizes of tomographic data grow with the development of more powerful acquisition hardware and more refined scientific needs. In the present paper we propose a new fast back-projection operator for the processing of tomographic data and compare it against other fast reconstruction techniques.

  1. Operating mode of high pressure straws with high spatial resolution

    CERN Document Server

    Davkov, K I; Peshekhonov, V D; Cholakov, V D

    2013-01-01

    The article presents results of studying the operating mode of thin-walled drift tubes (straws) at flushing it with a high-pressure gas mixture, which allowed obtaining extremely high spatial resolution for straw detectors. The results of studying the radiation ageing of straws operating in this mode are also described.

  2. Digital interface for high-resolution displays

    Science.gov (United States)

    Hermann, David J.; Gorenflo, Ronald L.

    1999-08-01

    Commercial display interfaces are currently transitioning from analog to digital. Although this transition is in the very early stages, the military needs to begin planning their own transition to digital. There are many problems with the analog interface in high-resolution display systems that are solved by changing to a digital interface. Also, display system cost can be lower with a digital interface to a high resolution display. Battelle is under contract with DARPA to develop an advanced Display Interface (ADI) to replace the analog RGB interfaces currently used in high definition workstation displays. The goal is to create a standard digital display interface for military applications that is based on emerging commercial standards. Support for military application- specific functionality is addressed, including display test and control. The main challenges to implementing a digital display interface are described, along with approaches to address the problems. Conceptual ADI architectures are described and contrasted. The current and emerging commercial standards for digital display interfaces are reviewed in detail. Finally, the tasks required to complete the ADI effort are outlined and described.

  3. Crusta: Visualizing High-resolution Global Data

    Science.gov (United States)

    Bernardin, T. S.; Kreylos, O.; Bowles, C. J.; Cowgill, E.; Hamann, B.; Kellogg, L. H.

    2009-12-01

    Virtual globes have become indispensable tools for visualizing, understanding and presenting data from Earth and other planetary bodies. The scientific community has invested much effort into exploiting existing globes to their fullest potential by refining and adapting their capabilities to better satisfy specific needs. For example, Google Earth provides users with the ability to view hillshade images derived from airborne LiDAR data such as the 2007 Northern California GeoEarthScope data. However, because most available globes were not designed with the specific needs of geoscientists in mind, shortcomings are becoming increasingly evident in geoscience applications such as terrain visualization. In particular, earth scientists struggle to visualize digital elevation models with both high spatial resolution (0.5 - 1 square meters per sample) and large extent (>2000 square kilometers), such as those obtained with airborne LiDAR. To address the specific earth science need of real-time terrain visualization of LiDAR data, we are developing Crusta as part of a close collaboration involving earth and computer scientists. Crusta is a new virtual globe that differs from widely used globes by both providing accurate global data representation and the ability to easily visualize custom topographic and image data. As a result, Crusta enables real-time, interactive visualization of high resolution digital elevation data spanning thousands of square kilometers, such as the complete 2007 Northern California GeoEarthScope airborne LiDAR data set. To implement an accurate data representation and avoid distortion of the display at the poles, where other projections have singularities, Crusta represents the globe as a thirty-sided polyhedron. Each side of this polyhedron can be subdivided to an arbitrarily fine grid on the surface of the globe, which allows Crusta to accommodate input data of arbitrary resolution ranging from global (e.g., Blue Marble) to local (e.g., a tripod

  4. High-resolution noncontact atomic force microscopy.

    Science.gov (United States)

    Pérez, Rubén; García, Ricardo; Schwarz, Udo

    2009-07-01

    original papers authored by many of the leading groups in the field with the goal of providing a well-balanced overview on the state-of-the-art in this rapidly evolving field. These papers, many of which are based on notable presentations given during the Madrid conference, feature highlights such as (1) the development of sophisticated force spectroscopy procedures that are able to map the complete 3D tip-sample force field on different surfaces; (2) the considerable resolution improvement of Kelvin probe force microscopy (reaching, in some cases, the atomic scale), which is accompanied by a thorough, quantitative understanding of the contrast observed; (3) the perfecting of atomic resolution imaging on insulating substrates, which helps reshape our microscopic understanding of surface properties and chemical activity of these surfaces; (4) the description of instrumental and methodological developments that pave the way to the atomic-scale characterization of magnetic and electronic properties of nanostructures, and last but not least (5) the extension of dynamic imaging modes to high-resolution operation in liquids, ultimately achieving atomic resolution. The latter developments are already having a significant impact in the highly competitive field of biological imaging under physiological conditions. This special issue of Nanotechnology would not have been possible without the highly professional support from Nina Couzin, Amy Harvey, Alex Wotherspoon and the entire Nanotechnology team at IOP Publishing. We are thankful for their help in pushing this project forward. We also thank the authors who have contributed their excellent original articles to this issue, the referees whose comments have helped make the issue an accurate portrait of this rapidly moving field, and the entire NC-AFM community that continues to drive NC-AFM to new horizons.

  5. Lung findings on high resolution CT in early ankylosing spondylitis

    Energy Technology Data Exchange (ETDEWEB)

    Kiris, Adem E-mail: ademkiris@hotmail.com; Ozgocmen, Salih; Kocakoc, Ercan; Ardicoglu, Ozge; Ogur, Erkin

    2003-07-01

    Objective: Ankylosing spondylitis (AS) is a chronic inflammatory disease mainly affecting the axial skeleton and pulmonary involvement is a well known feature of the disease. The aim of this study was to investigate the pulmonary high resolution computed tomography (HRCT) findings of patients with early AS. The relationship between pulmonary function tests (PFT) and HRCT findings was also determined. Subjects and methods: Twenty-eight patients with AS (mean age 30.8{+-}7.4 and disease duration 7.0{+-}2.6) were included in the study. Patients with a disease duration of >10 years or had other pulmonary diseases were excluded. All patients underwent plain chest radiography (posteroanterior and lateral views), thoracic HRCT and PFT. Results: All chest radiographs were normal and HRCT revealed abnormalities in 18 patients. The most common abnormalities seen on HRCT were mosaic pattern (ten of 28), subpleural nodule (seven of 28) and parenchymal bands (five of 28). Seven of ten patients with mosaic pattern revealed air trapping areas on end expiratory scans. Twelve patients had abnormal PFT and all had restrictive type of involvement. Ten of these 12 patients had abnormal HRCT and the remaining two patients had normal HRCT. On the other hand, eight patients with normal PFT had abnormalities on HRCT. Conclusion: Patients with early AS frequently have abnormalities on HRCT, even though they have normal PFT and chest X-ray. Small airway involvement was found as frequent as interstitial lung disease in early AS.

  6. Principles of high resolution NMR in solids

    CERN Document Server

    Mehring, Michael

    1983-01-01

    The field of Nuclear Magnetic Resonance (NMR) has developed at a fascinating pace during the last decade. It always has been an extremely valuable tool to the organic chemist by supplying molecular "finger print" spectra at the atomic level. Unfortunately the high resolution achievable in liquid solutions could not be obtained in solids and physicists and physical chemists had to live with unresolved lines open to a wealth of curve fitting procedures and a vast amount of speculations. High resolution NMR in solids seemed to be a paradoxon. Broad structure­ less lines are usually encountered when dealing with NMR in solids. Only with the recent advent of mUltiple pulse, magic angle, cross-polarization, two-dimen­ sional and multiple-quantum spectroscopy and other techniques during the last decade it became possible to resolve finer details of nuclear spin interactions in solids. I have felt that graduate students, researchers and others beginning to get involved with these techniques needed a book which trea...

  7. Limiting liability via high resolution image processing

    Energy Technology Data Exchange (ETDEWEB)

    Greenwade, L.E.; Overlin, T.K.

    1996-12-31

    The utilization of high resolution image processing allows forensic analysts and visualization scientists to assist detectives by enhancing field photographs, and by providing the tools and training to increase the quality and usability of field photos. Through the use of digitized photographs and computerized enhancement software, field evidence can be obtained and processed as `evidence ready`, even in poor lighting and shadowed conditions or darkened rooms. These images, which are most often unusable when taken with standard camera equipment, can be shot in the worst of photographic condition and be processed as usable evidence. Visualization scientists have taken the use of digital photographic image processing and moved the process of crime scene photos into the technology age. The use of high resolution technology will assist law enforcement in making better use of crime scene photography and positive identification of prints. Valuable court room and investigation time can be saved and better served by this accurate, performance based process. Inconclusive evidence does not lead to convictions. Enhancement of the photographic capability helps solve one major problem with crime scene photos, that if taken with standard equipment and without the benefit of enhancement software would be inconclusive, thus allowing guilty parties to be set free due to lack of evidence.

  8. High-Resolution Scintimammography: A Pilot Study

    Energy Technology Data Exchange (ETDEWEB)

    Rachel F. Brem; Joelle M. Schoonjans; Douglas A. Kieper; Stan Majewski; Steven Goodman; Cahid Civelek

    2002-07-01

    This study evaluated a novel high-resolution breast-specific gamma camera (HRBGC) for the detection of suggestive breast lesions. Methods: Fifty patients (with 58 breast lesions) for whom a scintimammogram was clinically indicated were prospectively evaluated with a general-purpose gamma camera and a novel HRBGC prototype. The results of conventional and high-resolution nuclear studies were prospectively classified as negative (normal or benign) or positive (suggestive or malignant) by 2 radiologists who were unaware of the mammographic and histologic results. All of the included lesions were confirmed by pathology. Results: There were 30 benign and 28 malignant lesions. The sensitivity for detection of breast cancer was 64.3% (18/28) with the conventional camera and 78.6% (22/28) with the HRBGC. The specificity with both systems was 93.3% (28/30). For the 18 nonpalpable lesions, sensitivity was 55.5% (10/18) and 72.2% (13/18) with the general-purpose camera and the HRBGC, respectively. For lesions 1 cm, 7 of 15 were detected with the general-purpose camera and 10 of 15 with the HRBGC. Four lesions (median size, 8.5 mm) were detected only with the HRBGC and were missed by the conventional camera. Conclusion: Evaluation of indeterminate breast lesions with an HRBGC results in improved sensitivity for the detection of cancer, with greater improvement shown for nonpalpable and 1-cm lesions.

  9. High-resolution light microscopy of nanoforms

    Science.gov (United States)

    Vodyanoy, Vitaly; Pustovyy, Oleg; Vainrub, Arnold

    2007-09-01

    We developed a high resolution light imaging system. Diffraction gratings with 100 nm width lines as well as less than 100 nm size features of different-shaped objects are clearly visible on a calibrated microscope test slide (Vainrub et al., Optics Letters, 2006, 31, 2855). The two-point resolution increase results from a known narrowing of the central diffraction peak for the annular aperture. Better visibility and advanced contrast of the smallest features in the image are due to enhancement of high spatial frequencies in the optical transfer function. The imaging system is portable, low energy, and battery operated. It has been adapted to use in both transmitting and reflecting light. It is particularly applicable for motile nanoform systems where structure and functions can be depicted in real time. We have isolated micrometer and submicrometer particles, termed proteons, from human and animal blood. Proteons form by reversible seeded aggregation of proteins around proteon nucleating centers (PNCs). PNCs are comprised of 1-2nm metallic nanoclusters containing 40-300 atoms. Proteons are capable of spontaneous assembling into higher nanoform systems assuming structure of complicated topology. The arrangement of complex proteon system mimics the structure of a small biological cell. It has structures that imitate membrane and nucleolus or nuclei. Some of these nanoforms are motile. They interact and divide. Complex nanoform systems can spontaneously reduce to simple proteons. The physical properties of these nanoforms could shed some light on the properties of early life forms or forms at extreme conditions.

  10. Venus gravity - A high-resolution map

    Science.gov (United States)

    Reasenberg, R. D.; Goldberg, Z. M.; Macneil, P. E.; Shapiro, I. I.

    1981-01-01

    The Doppler data from the radio tracking of the Pioneer Venus Orbiter (PVO) have been used in a two-stage analysis to develop a high-resolution map of the gravitational potential of Venus, represented by a central mass and a surface mass density. The two-stage procedure invokes a Kalman filter-smoother to determine the orbit of the spacecraft, and a stabilized linear inverter to estimate the surface mass density. The resultant gravity map is highly correlated with the topographic map derived from the PVO radar altimeter data. However, the magnitudes of the gravity variations are smaller than would be expected if the topography were uncompensated, indicating that at least partial compensation has taken place.

  11. Ultra-high resolution computed tomography imaging

    Energy Technology Data Exchange (ETDEWEB)

    Paulus, Michael J. (Knoxville, TN); Sari-Sarraf, Hamed (Knoxville, TN); Tobin, Jr., Kenneth William (Harriman, TN); Gleason, Shaun S. (Knoxville, TN); Thomas, Jr., Clarence E. (Knoxville, TN)

    2002-01-01

    A method for ultra-high resolution computed tomography imaging, comprising the steps of: focusing a high energy particle beam, for example x-rays or gamma-rays, onto a target object; acquiring a 2-dimensional projection data set representative of the target object; generating a corrected projection data set by applying a deconvolution algorithm, having an experimentally determined a transfer function, to the 2-dimensional data set; storing the corrected projection data set; incrementally rotating the target object through an angle of approximately 180.degree., and after each the incremental rotation, repeating the radiating, acquiring, generating and storing steps; and, after the rotating step, applying a cone-beam algorithm, for example a modified tomographic reconstruction algorithm, to the corrected projection data sets to generate a 3-dimensional image. The size of the spot focus of the beam is reduced to not greater than approximately 1 micron, and even to not greater than approximately 0.5 microns.

  12. Concept for a new high resolution high intensity diffractometer

    Energy Technology Data Exchange (ETDEWEB)

    Stuhr, U. [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

    1997-09-01

    A concept of a new time-of-flight powder-diffractometer for a thermal neutral beam tube at SINQ is presented. The design of the instrument optimises the contradictory conditions of high intensity and high resolution. The high intensity is achieved by using many neutron pulses simultaneously. By analysing the time-angle-pattern of the detected neutrons an assignment of the neutrons to a single pulse is possible. (author) 3 figs., tab., refs.

  13. A dedicated high-resolution PET imager for plant sciences.

    Science.gov (United States)

    Wang, Qiang; Mathews, Aswin J; Li, Ke; Wen, Jie; Komarov, Sergey; O'Sullivan, Joseph A; Tai, Yuan-Chuan

    2014-10-07

    PET provides an in vivo molecular and functional imaging capability that could be valuable for studying the interaction of plants in changing environments at the whole-plant level. We have developed a dedicated plant PET imager housed in a plant growth chamber (PGC), which provides a fully controlled environment. The system currently contains two types of scintillation detector modules from commercial small animal PET scanners: 84 microPET® detectors, which are made with scintillation crystal arrays of 2.2 mm(3) × 2.2 mm(3) × 10 mm(3) crystals to provide a large detection area; and 32 Inveon™ detectors, which are made with scintillation crystal arrays of 1.5 mm(3) × 1.5 mm(3) × 10 mm(3) crystals to provide higher spatial resolution. The detector modules are configured to form two half-rings, which provide a 15 cm-diameter trans-axial field of view (FOV) for dynamic tomographic imaging of small plants. Alternatively, the Inveon detectors can be reconfigured to form quarter-rings, which provide a 25 cm FOV using step-and-shoot motion. The imager contains two linear stages that move detectors vertically at different heights for multisection scanning, and two rotation stages to collect coincidence events from all angles when using the step-and-shoot acquisition. The detector modules and mechanical components of the imager are housed inside a PGC that regulates the environmental parameters. The system has a typical energy resolution of 15% for the Inveon detectors and 24% for the microPET detectors, timing resolution of 1.8 ns, and sensitivity of 1.3%, 1.4% and 3.0% measured at the center of the FOV, 5 cm off to the larger half-ring and 5 cm off to the smaller half-ring, respectively (with a 350-650 keV energy window and 3.1 ns timing window). The system's spatial resolution is capable of resolving rod sources of 1.25 mm diameter spaced 2.5 mm apart (center to center) using the ML-EM reconstruction algorithm. Preliminary imaging experiments

  14. High-resolution colorimetric imaging of paintings

    Science.gov (United States)

    Martinez, Kirk; Cupitt, John; Saunders, David R.

    1993-05-01

    With the aim of providing a digital electronic replacement for conventional photography of paintings, a scanner has been constructed based on a 3000 X 2300 pel resolution camera which is moved precisely over a 1 meter square area. Successive patches are assembled to form a mosaic which covers the whole area at c. 20 pels/mm resolution, which is sufficient to resolve the surface textures, particularly craquelure. To provide high color accuracy, a set of seven broad-band interference filters are used to cover the visible spectrum. A calibration procedure based upon a least-mean-squares fit to the color of patches from a Macbeth Colorchecker chart yields an average color accuracy of better than 3 units in the CMC uniform color space. This work was mainly carried out as part of the VASARI project funded by the European Commission's ESPRIT program, involving companies and galleries from around Europe. The system is being used to record images for conservation research, for archival purposes and to assist in computer-aided learning in the field of art history. The paper will describe the overall system design, including the selection of the various hardware components and the design of controlling software. The theoretical basis for the color calibration methodology is described as well as the software for its practical implementation. The mosaic assembly procedure and some of the associated image processing routines developed are described. Preliminary results from the research will be presented.

  15. High resolution CT of temporal bone trauma

    Energy Technology Data Exchange (ETDEWEB)

    Youn, Eun Kyung [Korea General Hospital, Seoul (Korea, Republic of)

    1986-10-15

    Radiographic studies of the temporal bone following head trauma are indicated when there is cerebrospinal fluid otorrhea or rhinorrhoea, hearing loss, or facial nerve paralysis. Plain radiography displays only 17-30% of temporal bone fractures and pluridirectional tomography is both difficult to perform, particularly in the acutely ill patient, and less satisfactory for the demonstration of fine fractures. Consequently, high resolution CT is the imaging method of choice for the investigation of suspected temporal bone trauma and allows special resolution of fine bony detail comparable to that attainable by conventional tomography. Eight cases of temporal bone trauma examined at Korea General Hospital April 1985 through May 1986. The results were as follows: Seven patients (87%) suffered longitudinal fractures. In 6 patients who had purely conductive hearing loss, CT revealed various ossicular chain abnormality. In one patient who had neuro sensory hearing loss, CT demonstrated intract ossicular with a fracture nearing lateral wall of the lateral semicircular canal. In one patient who had mixed hearing loss, CT showed complex fracture.

  16. High Resolution Radar Measurements of Snow Avalanches

    Science.gov (United States)

    McElwaine, Jim; Sovilla, Betty; Vriend, Nathalie; Brennan, Paul; Ash, Matt; Keylock, Chris

    2013-04-01

    Geophysical mass flows, such as snow avalanches, are a major hazard in mountainous areas and have a significant impact on the infrastructure, economy and tourism of such regions. Obtaining a thorough understanding of the dynamics of snow avalanches is crucial for risk assessment and the design of defensive structures. However, because the underlying physics is poorly understood there are significant uncertainties concerning current models, which are poorly validated due to a lack of high resolution data. Direct observations of the denser core of a large avalanche are particularly difficult, since it is frequently obscured by the dilute powder cloud. We have developed and installed a phased array FMCW radar system that penetrates the powder cloud and directly images the dense core with a resolution of around 1 m at 50 Hz over the entire slope. We present data from recent avalanches at Vallee de la Sionne that show a wealth of internal structure and allow the tracking of individual fronts, roll waves and surges down the slope for the first time. We also show good agreement between the radar results and existing measurement systems that record data at particular points on the avalanche track.

  17. Pyramidal fractal dimension for high resolution images

    Science.gov (United States)

    Mayrhofer-Reinhartshuber, Michael; Ahammer, Helmut

    2016-07-01

    Fractal analysis (FA) should be able to yield reliable and fast results for high-resolution digital images to be applicable in fields that require immediate outcomes. Triggered by an efficient implementation of FA for binary images, we present three new approaches for fractal dimension (D) estimation of images that utilize image pyramids, namely, the pyramid triangular prism, the pyramid gradient, and the pyramid differences method (PTPM, PGM, PDM). We evaluated the performance of the three new and five standard techniques when applied to images with sizes up to 8192 × 8192 pixels. By using artificial fractal images created by three different generator models as ground truth, we determined the scale ranges with minimum deviations between estimation and theory. All pyramidal methods (PM) resulted in reasonable D values for images of all generator models. Especially, for images with sizes ≥1024 ×1024 pixels, the PMs are superior to the investigated standard approaches in terms of accuracy and computation time. A measure for the possibility to differentiate images with different intrinsic D values did show not only that the PMs are well suited for all investigated image sizes, and preferable to standard methods especially for larger images, but also that results of standard D estimation techniques are strongly influenced by the image size. Fastest results were obtained with the PDM and PGM, followed by the PTPM. In terms of absolute D values best performing standard methods were magnitudes slower than the PMs. Concluding, the new PMs yield high quality results in short computation times and are therefore eligible methods for fast FA of high-resolution images.

  18. Estimation of the Axial Stress in High-Tension Bolt by Acoustoelastic Method

    Energy Technology Data Exchange (ETDEWEB)

    Chun, Hae Hwa; Lee, Tae Hoon; Jhang, Kyung Young [Hanyang University, Seoul (Korea, Republic of); Kim, Noh Yu [Korea University of Technology and Education, Cheonan (Korea, Republic of)

    2006-10-15

    The evaluation of clamping condition has been regarded as the main issue in the safety-maintenance of the clamped high-tension bolts. For this, this paper proposes a method to estimate the axial stress by measuring the Tofu (Time-Of-Flight) of ultrasonic wave, which is based on the acetylsalicylate or the dependency of sound speed on the stress. In this method, however, the variation of sound speed within the range of stress induced under the field condition is very small, and thus the accuracy of the Tofu measurement is important. We adopted the phase detection method using tone-burst ultrasonic wave to measure the precise Tofu. In order to verify the usefulness of the proposed method experiments are carried out and the results were compared with the stress measured by the strain gage. The results show good agreement with each other, and from these we can conclude that the proposed method is highly useful fnr the evaluation of clamping condition in the clamped high-tension bolts

  19. High-resolution harmonic motion imaging (HR-HMI) for tissue biomechanical property characterization.

    Science.gov (United States)

    Ma, Teng; Qian, Xuejun; Chiu, Chi Tat; Yu, Mingyue; Jung, Hayong; Tung, Yao-Sheng; Shung, K Kirk; Zhou, Qifa

    2015-02-01

    Elastography, capable of mapping the biomechanical properties of biological tissues, serves as a useful technique for clinicians to perform disease diagnosis and determine stages of many diseases. Many acoustic radiation force (ARF) based elastography, including acoustic radiation force impulse (ARFI) imaging and harmonic motion imaging (HMI), have been developed to remotely assess the elastic properties of tissues. However, due to the lower operating frequencies of these approaches, their spatial resolutions are insufficient for revealing stiffness distribution on small scale applications, such as cancerous tumor margin detection, atherosclerotic plaque composition analysis and ophthalmologic tissue characterization. Though recently developed ARF-based optical coherence elastography (OCE) methods open a new window for the high resolution elastography, shallow imaging depths significantly limit their usefulness in clinics. The aim of this study is to develop a high-resolution HMI method to assess the tissue biomechanical properties with acceptable field of view (FOV) using a 4 MHz ring transducer for efficient excitation and a 40 MHz needle transducer for accurate detection. Under precise alignment of two confocal transducers, the high-resolution HMI system has a lateral resolution of 314 µm and an axial resolution of 
147 µm with an effective FOV of 2 mm in depth. The performance of this high resolution imaging system was validated on the agar-based tissue mimicking phantoms with different stiffness distributions. These data demonstrated the imaging system's improved resolution and sensitivity on differentiating materials with varying stiffness. In addition, ex vivo imaging of a human atherosclerosis coronary artery demonstrated the capability of high resolution HMI in identifying layer-specific structures and characterizing atherosclerotic plaques based on their stiffness differences. All together high resolution HMI appears to be a promising ultrasound

  20. Detection of proximal caries with high-resolution and standard resolution digital radiographic systems

    NARCIS (Netherlands)

    Berkhout, W.E.R.; Verheij, H.G.C.; Syriopoulos, K.; Li, G.; Sanderink, G.C.H.; van der Stelt, P.F.

    2007-01-01

    Aims: The aim of this study was to: (1) compare the diagnostic accuracy of the high-resolution and standard resolution settings of four digital imaging systems for caries diagnosis and (2) compare the effect on the diagnostic accuracy of reducing the high-resolution image sizes to the standard

  1. Axially connected nanowire core-shell p-n junctions: a composite structure for high-efficiency solar cells.

    Science.gov (United States)

    Wang, Sijia; Yan, Xin; Zhang, Xia; Li, Junshuai; Ren, Xiaomin

    2015-01-01

    A composite nanostructure for high-efficiency solar cells that axially connects nanowire core-shell p-n junctions is proposed. By axially connecting the p-n junctions in one nanowire, the solar spectrum is separated and absorbed in the top and bottom cells with respect to the wavelength. The unique structure of nanowire p-n junctions enables substantial light absorption along the nanowire and efficient radial carrier separation and collection. A coupled three-dimensional optoelectronic simulation is used to evaluate the performance of the structure. With an excellent current matching, a promising efficiency of 19.9% can be achieved at a low filling ratio of 0.283 (the density of the nanowire array), which is much higher than the tandem axial p-n junctions.

  2. Improved methods for high resolution electron microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, J.R.

    1987-04-01

    Existing methods of making support films for high resolution transmission electron microscopy are investigated and novel methods are developed. Existing methods of fabricating fenestrated, metal reinforced specimen supports (microgrids) are evaluated for their potential to reduce beam induced movement of monolamellar crystals of C/sub 44/H/sub 90/ paraffin supported on thin carbon films. Improved methods of producing hydrophobic carbon films by vacuum evaporation, and improved methods of depositing well ordered monolamellar paraffin crystals on carbon films are developed. A novel technique for vacuum evaporation of metals is described which is used to reinforce microgrids. A technique is also developed to bond thin carbon films to microgrids with a polymer bonding agent. Unique biochemical methods are described to accomplish site specific covalent modification of membrane proteins. Protocols are given which covalently convert the carboxy terminus of papain cleaved bacteriorhodopsin to a free thiol. 53 refs., 19 figs., 1 tab.

  3. A new high-resolution TOF technology

    CERN Document Server

    Fonte, Paulo J R; Williams, M C S

    2000-01-01

    In the framework of the ALICE collaboration we have recently studied the performance of multigap Resistive Plate Chambers operated in avalanche mode and at atmospheric pressure for time-of-flight measurements. The detector provided an overall (detector plus electronics) timing accuracy of 120 ps sigma at an efficiency of 98% for MIPs. The chambers had 4 gas gaps of 0.3 mm, each limited by a metallised ceramic plate and a glass plate, with an active dimension of 4'4cm2. The gas mixture contained C2H2F4+5%isobutane+10%SF6. A few percent of streamer discharges, each releasing about 20 pC, was tolerated without any noticeable inconvenience. This detector opens perspectives of affordable and reliable high granularity large area TOF detectors, with an efficiency and a time resolution comparable to existing scintillator-based TOF technology but with significantly, up to an order of magnitude, lower price per channel.

  4. Capillary detectors for high resolution tracking

    CERN Document Server

    Annis, P

    1997-01-01

    We present a new tracking device based on glass capillary bundles or layers filled with highly purified liquid scintillator and read out at one end by means of image intensifiers and CCD devices. A large-volume prototype consisting of 5 × 105 capillaries with a diameter of 20 μm and a length of 180 cm and read out by a megapixel CCD has been tested with muon and neutrino beams at CERN. With this prototype a two track resolution of 33 μm was achieved with passing through muons. Images of neutrino interactions in a capillary bundle have also been acquired and analysed. Read-out chains based on Electron Bombarded CCD (EBCCD) and image pipeline devices are also investigated. Preliminary results obtained with a capillary bundle read out by an EBCCD are presented.

  5. Speleothems as high-resolution paleoflood archives

    Science.gov (United States)

    Denniston, Rhawn F.; Luetscher, Marc

    2017-08-01

    Over the last two decades, speleothems have become widely utilized records of past environmental variability, typically through their stable isotopic and trace elemental chemistry. Numerous speleothem researchers have identified evidence of flooding recorded by detrital layers trapped within speleothems, but few studies have developed paleoflood reconstructions from such samples. Because they can be precisely dated, are generally immune to post-depositional distortion or erosion, and can be tied to a fixed elevational baseline, speleothems hold enormous potential as high-resolution archives of cave floods, and thus as proxies for extreme rainfall or other hydrologic drivers of cave flooding. Here we review speleothem-based paleoflood reconstruction methods, identify potential biases and pitfalls, and suggest standard practices for future studies.

  6. High-resolution CT of otosclerosis

    Energy Technology Data Exchange (ETDEWEB)

    Dewen, Yang; Kodama, Takao; Tono, Tetsuya; Ochiai, Reiji; Kiyomizu, Kensuke; Suzuki, Yukiko; Yano, Takanori; Watanabe, Katsushi [Miyazaki Medical Coll., Kiyotake (Japan)

    1997-11-01

    High-resolution CT (HRCT) scans of thirty-two patients (60 ears) with the clinical diagnosis of fenestral otosclerosis were evaluated retrospectively. HRCT was performed with 1-mm-thick targeted sections and 1-mm (36 ears) or 0.5-mm (10 ears) intervals in the semiaxial projection. Seven patients (14 ears) underwent helical scanning with a 1-mm slice thickness and 1-mm/sec table speed. Forty-five ears (75%) were found to have one or more otospongiotic or otosclerotic foci on HRCT. In most instances (30 ears), the otospongiotic foci were found in the region of the fissula ante fenestram. No significant correlations between CT findings and air conduction threshold were observed. We found a significant relationship between lesions of the labyrinthine capsule and sensorineural hearing loss. We conclude that HRCT is a valuable modality for diagnosing otosclerosis, especially when otospongiotic focus is detected. (author)

  7. High resolution imaging detectors and applications

    CERN Document Server

    Saha, Swapan K

    2015-01-01

    Interferometric observations need snapshots of very high time resolution of the order of (i) frame integration of about 100 Hz or (ii) photon-recording rates of several megahertz (MHz). Detectors play a key role in astronomical observations, and since the explanation of the photoelectric effect by Albert Einstein, the technology has evolved rather fast. The present-day technology has made it possible to develop large-format complementary metal oxide–semiconductor (CMOS) and charge-coupled device (CCD) array mosaics, orthogonal transfer CCDs, electron-multiplication CCDs, electron-avalanche photodiode arrays, and quantum-well infrared (IR) photon detectors. The requirements to develop artifact-free photon shot noise-limited images are higher sensitivity and quantum efficiency, reduced noise that includes dark current, read-out and amplifier noise, smaller point-spread functions, and higher spectral bandwidth. This book aims to address such systems, technologies and design, evaluation and calibration, control...

  8. GRANULOMETRIC MAPS FROM HIGH RESOLUTION SATELLITE IMAGES

    Directory of Open Access Journals (Sweden)

    Catherine Mering

    2011-05-01

    Full Text Available A new method of land cover mapping from satellite images using granulometric analysis is presented here. Discontinuous landscapes such as steppian bushes of semi arid regions and recently growing urban settlements are especially concerned by this study. Spatial organisations of the land cover are quantified by means of the size distribution analysis of the land cover units extracted from high resolution remotely sensed images. A granulometric map is built by automatic classification of every pixel of the image according to the granulometric density inside a sliding neighbourhood. Granulometric mapping brings some advantages over traditional thematic mapping by remote sensing by focusing on fine spatial events and small changes in one peculiar category of the landscape.

  9. High resolution CT of Meckel's cave.

    Science.gov (United States)

    Chui, M; Tucker, W; Hudson, A; Bayer, N

    1985-01-01

    High resolution CT of the parasellar region was carried out in 50 patients studied for suspected pituitary microadenoma, but who showed normal pituitary gland or microadenoma on CT. This control group of patients all showed an ellipsoid low-density area in the posterior parasellar region. Knowledge of the gross anatomy and correlation with metrizamide cisternography suggest that the low density region represents Meckel's cave, rather than just the trigeminal ganglion alone. Though there is considerable variation in the size of Meckel's cave in different patients as well as the two sides of the same patient, the rather constant ellipsoid configuration of the cave in normal subjects will aid in diagnosing small pathological lesions, thereby obviating more invasive cisternography via the transovale or lumbar route. Patients with "idiopathic" tic douloureux do not show a Meckel's cave significantly different from the control group.

  10. Georadar - high resolution geophysical electromagnetic device

    Directory of Open Access Journals (Sweden)

    Janez Stern

    1995-12-01

    Full Text Available Georadar is a high resolution geophysical electromagnetic device that was developed in the first part of the 1980's. In Slovenia it was first tested in 1991 on several objects of economicgeological, geotechnical and hydrogeologic nature.Here its usefulness in karst studied is presented. The first part of the paper deals with description of measurement procedure and methodological bases, and the second part with experience and results of case histories. Shown are radargrams from ornamental stone quarry Hotavlje, calcite mine Stahovica, Golobja jama karstcave near Divača and from highway construction site Razdrto-Čebulovica. All measurements were performed with the georadar instrument Pulse EKKO IV with a lOOMHz antenna according to the method of reflection profiling.

  11. Potential High Resolution Dosimeters For MRT

    Science.gov (United States)

    Bräuer-Krisch, E.; Rosenfeld, A.; Lerch, M.; Petasecca, M.; Akselrod, M.; Sykora, J.; Bartz, J.; Ptaszkiewicz, M.; Olko, P.; Berg, A.; Wieland, M.; Doran, S.; Brochard, T.; Kamlowski, A.; Cellere, G.; Paccagnella, A.; Siegbahn, E. A.; Prezado, Y.; Martinez-Rovira, I.; Bravin, A.; Dusseau, L.; Berkvens, P.

    2010-07-01

    Microbeam Radiation Therapy (MRT) uses highly collimated, quasi-parallel arrays of X-ray microbeams of 50-600 keV, produced by 2nd and 3rd generation synchrotron sources, such as the National Synchrotron Light Source (NSLS) in the U.S., and the European Synchrotron Radiation Facility (ESRF) in France, respectively. High dose rates are necessary to deliver therapeutic doses in microscopic volumes, to avoid spreading of the microbeams by cardiosynchronous movement of the tissues. A small beam divergence and a filtered white beam spectrum in the energy range between 30 and 250 keV results in the advantage of steep dose gradients with a sharper penumbra than that produced in conventional radiotherapy. MRT research over the past 20 years has allowed a vast number of results from preclinical trials on different animal models, including mice, rats, piglets and rabbits. Microbeams in the range between 10 and 100 micron width show an unprecedented sparing of normal radiosensitive tissues as well as preferential damage to malignant tumor tissues. Typically, MRT uses arrays of narrow (˜25-100 micron-wide) microplanar beams separated by wider (100-400 microns centre-to-centre, c-t-c) microplanar spaces. We note that thicker microbeams of 0.1-0.68 mm used by investigators at the NSLS are still called microbeams, although some invesigators in the community prefer to call them minibeams. This report, however, limits it discussion to 25-100 μm microbeams. Peak entrance doses of several hundreds of Gy are surprisingly well tolerated by normal tissues. High resolution dosimetry has been developed over the last two decades, but typical dose ranges are adapted to dose delivery in conventional Radiation Therapy (RT). Spatial resolution in the sub-millimetric range has been achieved, which is currently required for quality assurance measurements in Gamma-knife RT. Most typical commercially available detectors are not suitable for MRT applications at a dose rate of 16000 Gy/s, micron

  12. High-Resolution Movement EEG Classification

    Directory of Open Access Journals (Sweden)

    Jakub Štastný

    2007-01-01

    Full Text Available The aim of the contribution is to analyze possibilities of high-resolution movement classification using human EEG. For this purpose, a database of the EEG recorded during right-thumb and little-finger fast flexion movements of the experimental subjects was created. The statistical analysis of the EEG was done on the subject's basis instead of the commonly used grand averaging. Statistically significant differences between the EEG accompanying movements of both fingers were found, extending the results of other so far published works. The classifier based on hidden Markov models was able to distinguish between movement and resting states (classification score of 94–100%, but it was unable to recognize the type of the movement. This is caused by the large fraction of other (nonmovement related EEG activities in the recorded signals. A classification method based on advanced EEG signal denoising is being currently developed to overcome this problem.

  13. High-resolution transcriptome of human macrophages.

    Directory of Open Access Journals (Sweden)

    Marc Beyer

    Full Text Available Macrophages are dynamic cells integrating signals from their microenvironment to develop specific functional responses. Although, microarray-based transcriptional profiling has established transcriptional reprogramming as an important mechanism for signal integration and cell function of macrophages, current knowledge on transcriptional regulation of human macrophages is far from complete. To discover novel marker genes, an area of great need particularly in human macrophage biology but also to generate a much more thorough transcriptome of human M1- and M1-like macrophages, we performed RNA sequencing (RNA-seq of human macrophages. Using this approach we can now provide a high-resolution transcriptome profile of human macrophages under classical (M1-like and alternative (M2-like polarization conditions and demonstrate a dynamic range exceeding observations obtained by previous technologies, resulting in a more comprehensive understanding of the transcriptome of human macrophages. Using this approach, we identify important gene clusters so far not appreciated by standard microarray techniques. In addition, we were able to detect differential promoter usage, alternative transcription start sites, and different coding sequences for 57 gene loci in human macrophages. Moreover, this approach led to the identification of novel M1-associated (CD120b, TLR2, SLAMF7 as well as M2-associated (CD1a, CD1b, CD93, CD226 cell surface markers. Taken together, these data support that high-resolution transcriptome profiling of human macrophages by RNA-seq leads to a better understanding of macrophage function and will form the basis for a better characterization of macrophages in human health and disease.

  14. A comparative study of complications of cataract surgery with phacoemulsification in eyes with high and normal axial length

    Directory of Open Access Journals (Sweden)

    Hamid Fesharaki

    2012-01-01

    Conclusions: As the results illustrate, in this survey, age and high axial length were statistically significant risk factors for incidence of intraoperative complications of cataract surgery with phacoemulsification technique. Anticipation of these complications and also preparation and prophylactic measures may decrease incidence of these complications.

  15. High-resolution downscaling for hydrological management

    Science.gov (United States)

    Ulbrich, Uwe; Rust, Henning; Meredith, Edmund; Kpogo-Nuwoklo, Komlan; Vagenas, Christos

    2017-04-01

    Hydrological modellers and water managers require high-resolution climate data to model regional hydrologies and how these may respond to future changes in the large-scale climate. The ability to successfully model such changes and, by extension, critical infrastructure planning is often impeded by a lack of suitable climate data. This typically takes the form of too-coarse data from climate models, which are not sufficiently detailed in either space or time to be able to support water management decisions and hydrological research. BINGO (Bringing INnovation in onGOing water management; ) aims to bridge the gap between the needs of hydrological modellers and planners, and the currently available range of climate data, with the overarching aim of providing adaptation strategies for climate change-related challenges. Producing the kilometre- and sub-daily-scale climate data needed by hydrologists through continuous simulations is generally computationally infeasible. To circumvent this hurdle, we adopt a two-pronged approach involving (1) selective dynamical downscaling and (2) conditional stochastic weather generators, with the former presented here. We take an event-based approach to downscaling in order to achieve the kilometre-scale input needed by hydrological modellers. Computational expenses are minimized by identifying extremal weather patterns for each BINGO research site in lower-resolution simulations and then only downscaling to the kilometre-scale (convection permitting) those events during which such patterns occur. Here we (1) outline the methodology behind the selection of the events, and (2) compare the modelled precipitation distribution and variability (preconditioned on the extremal weather patterns) with that found in observations.

  16. The high resolution neutrino calorimeter KARMEN

    Energy Technology Data Exchange (ETDEWEB)

    Drexlin, G.; Eberhard, V.; Gemmeke, H.; Giorginis, G.; Grandegger, W.; Gumbsheimer, R.; Hucker, H.; Husson, L.; Kleinfeller, J.; Maschuw, R.; Plischke, P.; Spohrer, G.; Schmidt, F.K.; Wochele, J.; Woelfle, S.; Zeitnitz, B. (Kernforschungszentrum Karlsruhe GmbH (Germany, F.R.). Inst. fuer Kernphysik 1 Karlsruhe Univ. (T.H.) (Germany, F.R.). Inst. fuer Experimentelle Kernphysik); Bodman, B.; Burtak, F.; Finckh, E.; Glombik, A.; Kretschmer, W.; Schilling, F.; Voetisch, D. (Erlangen-Nuernberg Univ., Erlangen (Germany, F.R.). Physikalisches Inst.); Edgington, J.A.; Gorringe, T.; Malik, A. (Queen Mary Coll., London (UK)); Booth, N.E. (Oxford Univ. (UK)); Dodd, A.; Payne, A.G.D. (Rutherford Appleton Lab., Chilton (UK))

    1990-04-15

    KARMEN is a 56 t scintillation calorimeter designed for beam dump neutrino experiments at the neutron spallation facility ISIS of the Rutherford Appleton Laboratory. The calorimetric properties are demonstrated by cosmic muons and laser calibration. The measured energy resolution of the detector is {sigma}{sub E}/E{approx equal}11.5%/{radical}E(MeV), the position resolution {sigma}{sub x}=5 cm and the timing resolution {sigma}{sub t}{approx equal}350 ps. (orig.).

  17. High resolution image reconstruction from projection of low resolution images differing in subpixel shifts

    Science.gov (United States)

    Mareboyana, Manohar; Le Moigne, Jacqueline; Bennett, Jerome

    2016-05-01

    In this paper, we demonstrate simple algorithms that project low resolution (LR) images differing in subpixel shifts on a high resolution (HR) also called super resolution (SR) grid. The algorithms are very effective in accuracy as well as time efficiency. A number of spatial interpolation techniques using nearest neighbor, inverse-distance weighted averages, Radial Basis Functions (RBF) etc. are used in projection. For best accuracy of reconstructing SR image by a factor of two requires four LR images differing in four independent subpixel shifts. The algorithm has two steps: i) registration of low resolution images and (ii) shifting the low resolution images to align with reference image and projecting them on high resolution grid based on the shifts of each low resolution image using different interpolation techniques. Experiments are conducted by simulating low resolution images by subpixel shifts and subsampling of original high resolution image and the reconstructing the high resolution images from the simulated low resolution images. The results of accuracy of reconstruction are compared by using mean squared error measure between original high resolution image and reconstructed image. The algorithm was tested on remote sensing images and found to outperform previously proposed techniques such as Iterative Back Projection algorithm (IBP), Maximum Likelihood (ML) algorithms. The algorithms are robust and are not overly sensitive to the registration inaccuracies.

  18. High Resolution Image Reconstruction from Projection of Low Resolution Images DIffering in Subpixel Shifts

    Science.gov (United States)

    Mareboyana, Manohar; Le Moigne-Stewart, Jacqueline; Bennett, Jerome

    2016-01-01

    In this paper, we demonstrate a simple algorithm that projects low resolution (LR) images differing in subpixel shifts on a high resolution (HR) also called super resolution (SR) grid. The algorithm is very effective in accuracy as well as time efficiency. A number of spatial interpolation techniques using nearest neighbor, inverse-distance weighted averages, Radial Basis Functions (RBF) etc. used in projection yield comparable results. For best accuracy of reconstructing SR image by a factor of two requires four LR images differing in four independent subpixel shifts. The algorithm has two steps: i) registration of low resolution images and (ii) shifting the low resolution images to align with reference image and projecting them on high resolution grid based on the shifts of each low resolution image using different interpolation techniques. Experiments are conducted by simulating low resolution images by subpixel shifts and subsampling of original high resolution image and the reconstructing the high resolution images from the simulated low resolution images. The results of accuracy of reconstruction are compared by using mean squared error measure between original high resolution image and reconstructed image. The algorithm was tested on remote sensing images and found to outperform previously proposed techniques such as Iterative Back Projection algorithm (IBP), Maximum Likelihood (ML), and Maximum a posterior (MAP) algorithms. The algorithm is robust and is not overly sensitive to the registration inaccuracies.

  19. Flow performance of highly loaded axial fan with bowed rotor blades

    Science.gov (United States)

    Chen, L.; Liu, X. J.; Yang, A. L.; Dai, R.

    2013-12-01

    In this paper, a partial bowed rotor blade was proposed for a newly designed high loaded axial fan. The blade was positively bowed 30 degrees from hub to 30 percent spanwise position. Flows of radial blade and bowed blade fans were numerically compared for various operation conditions. Results show that the fan's performance is improved. At the designed condition with flow coefficient of 0.52, the efficiency of the bowed blade fan is increased 1.44% and the static pressure rise is increased 11%. Comparing the flow structures, it can be found that the separated flow in the bowed fan is reduced and confined within 20 percent span, which is less than the 35 percent in the radial fan. It means that the bowed blade generates negative blade force and counteracts partial centrifugal force. It is alleviates the radial movements of boundary layers in fan's hub region. Flow losses due to 3D mixing are reduced in the rotor. Inlet flow to downstream stator is also improved.

  20. A Developed Methodology in Design of Highly Loaded Tandem Axial Flow Compressor Stage

    Directory of Open Access Journals (Sweden)

    Masoud Boroomand

    2016-01-01

    Full Text Available This study, primarily reports the development of a 3D design procedure for axial flow tandem compressor stages and then the method is used to design a highly loaded tandem stage. In order to investigate the effects of such arrangement, another stage with conventional loading with single blade for both rotor and stator rows is designed with similar specification. In order to ease the comparison of results, chord lengths and hub/shroud geometries are selected with the same dimensions. At the next stage a three dimensional numerical model is developed to predict the characteristic performance of both tandem and conventional stages. The model is validated with the experimental results of NASA-67 stage and the level of the accuracy of the model is presented. Employing the model to simulate the performance of both stages at design and offdesign operating points show that, tandem stage can provide higher pressure ratio with acceptable efficiency. In another word, tandem stage is capable having the same pressure ratio at lower rotational speed. The safe operation domain and loss mechanism in tandem stage are also discussed in this report.

  1. High Resolution Airborne Shallow Water Mapping

    Science.gov (United States)

    Steinbacher, F.; Pfennigbauer, M.; Aufleger, M.; Ullrich, A.

    2012-07-01

    In order to meet the requirements of the European Water Framework Directive (EU-WFD), authorities face the problem of repeatedly performing area-wide surveying of all kinds of inland waters. Especially for mid-sized or small rivers this is a considerable challenge imposing insurmountable logistical efforts and costs. It is therefore investigated if large-scale surveying of a river system on an operational basis is feasible by employing airborne hydrographic laser scanning. In cooperation with the Bavarian Water Authority (WWA Weilheim) a pilot project was initiated by the Unit of Hydraulic Engineering at the University of Innsbruck and RIEGL Laser Measurement Systems exploiting the possibilities of a new LIDAR measurement system with high spatial resolution and high measurement rate to capture about 70 km of riverbed and foreland for the river Loisach in Bavaria/Germany and the estuary and parts of the shoreline (about 40km in length) of lake Ammersee. The entire area surveyed was referenced to classic terrestrial cross-section surveys with the aim to derive products for the monitoring and managing needs of the inland water bodies forced by the EU-WFD. The survey was performed in July 2011 by helicopter and airplane and took 3 days in total. In addition, high resolution areal images were taken to provide an optical reference, offering a wide range of possibilities on further research, monitoring, and managing responsibilities. The operating altitude was about 500 m to maintain eye-safety, even for the aided eye, the airspeed was about 55 kts for the helicopter and 75 kts for the aircraft. The helicopter was used in the alpine regions while the fixed wing aircraft was used in the plains and the urban area, using appropriate scan rates to receive evenly distributed point clouds. The resulting point density ranged from 10 to 25 points per square meter. By carefully selecting days with optimum water quality, satisfactory penetration down to the river bed was achieved

  2. Logging Data High-Resolution Sequence Stratigraphy

    Institute of Scientific and Technical Information of China (English)

    Li Hongqi; Xie Yinfu; Sun Zhongchun; Luo Xingping

    2006-01-01

    The recognition and contrast of bed sets in parasequence is difficult in terrestrial basin high-resolution sequence stratigraphy. This study puts forward new methods for the boundary identification and contrast of bed sets on the basis of manifold logging data. The formation of calcareous interbeds, shale resistivity differences and the relation of reservoir resistivity to altitude are considered on the basis of log curve morphological characteristics, core observation, cast thin section, X-ray diffraction and scanning electron microscopy. The results show that the thickness of calcareous interbeds is between 0.5 m and 2 m, increasing on weathering crusts and faults. Calcareous interbeds occur at the bottom of Reservoir resistivity increases with altitude. Calcareous interbeds may be a symbol of recognition for the boundary of bed sets and isochronous contrast bed sets, and shale resistivity differences may confirm the stack relation and connectivity of bed sets. Based on this, a high-rcsolution chronostratigraphic framework of Xi-1 segment in Shinan area, Junggar basin is presented, and the connectivity of bed sets and oil-water contact is confirmed. In this chronostratigraphic framework, the growth order, stack mode and space shape of bed sets are qualitatively and quantitatively described.

  3. High resolution low frequency ultrasonic tomography.

    Science.gov (United States)

    Lasaygues, P; Lefebvre, J P; Mensah, S

    1997-10-01

    Ultrasonic reflection tomography results from a linearization of the inverse acoustic scattering problem, named the inverse Born approximation. The goal of ultrasonic reflection tomography is to obtain reflectivity images from backscattered measurements. This is a Fourier synthesis problem and the first step is to correctly cover the frequency space of the object. For this inverse problem, we use the classical algorithm of tomographic reconstruction by summation of filtered backprojections. In practice, only a limited number of views are available with our mechanical rig, typically 180, and the frequency bandwidth of the pulses is very limited, typically one octave. The resolving power of the system is them limited by the bandwidth of the pulse. Low and high frequencies can be restored by use of a deconvolution algorithm that enhances resolution. We used a deconvolution technique based on the Papoulis method. The advantage of this technique is conservation of the overall frequency information content of the signals. The enhancement procedure was tested by imaging a square aluminium rod with a cross-section less than the wavelength. In this application, the central frequency of the transducer was 250 kHz so that the central wavelength was 6 mm whereas the cross-section of the rod was 4 mm. Although the Born approximation was not theoretically valid in this case (high contrast), a good reconstruction was obtained.

  4. Automatic abundance analysis of high resolution spectra

    CERN Document Server

    Bonifacio, P; Bonifacio, Piercarlo; Caffau, Elisabetta

    2003-01-01

    We describe an automatic procedure for determining abundances from high resolution spectra. Such procedures are becoming increasingly important as large amounts of data are delivered from 8m telescopes and their high-multiplexing fiber facilities, such as FLAMES on ESO-VLT. The present procedure is specifically targeted for the analysis of spectra of giants in the Sgr dSph; however, the procedure may be, in principle, tailored to analyse stars of any type. Emphasis is placed on the algorithms and on the stability of the method; the external accuracy rests, ultimately, on the reliability of the theoretical models (model-atmospheres, synthetic spectra) used to interpret the data. Comparison of the results of the procedure with the results of a traditional analysis for 12 Sgr giants shows that abundances accurate at the level of 0.2 dex, comparable with that of traditional analysis of the same spectra, may be derived in a fast and efficient way. Such automatic procedures are not meant to replace the traditional ...

  5. Supporting observation campaigns with high resolution modeling

    Science.gov (United States)

    Klocke, Daniel; Brueck, Matthias; Voigt, Aiko

    2017-04-01

    High resolution simulation in support of measurement campaigns offers a promising and emerging way to create large-scale context for small-scale observations of clouds and precipitation processes. As these simulation include the coupling of measured small-scale processes with the circulation, they also help to integrate the research communities from modeling and observations and allow for detailed model evaluations against dedicated observations. In connection with the measurement campaign NARVAL (August 2016 and December 2013) simulations with a grid-spacing of 2.5 km for the tropical Atlantic region (9000x3300 km), with local refinement to 1.2 km for the western part of the domain, were performed using the icosahedral non-hydrostatic (ICON) general circulation model. These simulations are again used to drive large eddy resolving simulations with the same model for selected days in the high definition clouds and precipitation for advancing climate prediction (HD(CP)2) project. The simulations are presented with the focus on selected results showing the benefit for the scientific communities doing atmospheric measurements and numerical modeling of climate and weather. Additionally, an outlook will be given on how similar simulations will support the NAWDEX measurement campaign in the North Atlantic and AC3 measurement campaign in the Arctic.

  6. STUDY OF POSTERIOR FOSSA TUMORS BY HIGH RESOLUTION MRI

    Directory of Open Access Journals (Sweden)

    Sree Hari

    2016-01-01

    Full Text Available INTRODUCTION Magnetic Resonance Imaging (MRI is the imaging modality used for the assessment of infratentorial neoplasms. Although Computed Tomography (CT provides better demonstration of small or subtle calcifications within tumors. OBJECTIVES Study is done to assess the potential of MRI in characterisation of different tumors in posterior fossa by evaluating various unenhanced and gadolinium enhanced sequences and to compare high resolution FSE MRI sequences with routine FSE MRI sequences in diagnosing posterior fossa brain tumors. Also correlate findings on Magnetic Resonance Imaging with Pathological diagnosis. MATERIALS AND METHODS A total of 52 patients were diagnosed by CT brain as having posterior fossa brain for a year of 2 years were included in the study. In all studies MR imaging was performed with a clinical 1.5 T system (General electrical medical systems. A dedicated phased-array coil was used. RESULTS The age group ranged from 1 year to 60 years, majority were between 1 to 20 years (39%. Slight male preponderance was seen (males 29, females 23. Commonest tumor encountered in our study was vestibular schwannoma. DWI alone can differentiate different pediatric posterior fossa brain tumors. One case of pilocytic astrocytoma showed solid lesion instead of typical cystic lesion with mural nodule. One case AT-RT showed 2 lesions one in cerebrum, one in CP angle. Common feature being intra-axial lesion involving cerebellum. MRI was able to predict diagnosis in 50 of the 52 tumors. CONCLUSION Magnetic Resonance Imaging was found to be a highly sensitive imaging procedure and method of choice for posterior fossa brain tumors.

  7. Resolution enhancement of low quality videos using a high-resolution frame

    NARCIS (Netherlands)

    Pham, T.Q.; Van Vliet, L.J.; Schutte, K.

    2006-01-01

    This paper proposes an example-based Super-Resolution (SR) algorithm of compressed videos in the Discrete Cosine Transform (DCT) domain. Input to the system is a Low-Resolution (LR) compressed video together with a High-Resolution (HR) still image of similar content. Using a training set of correspo

  8. Genetic variants on chromosome 1q41 influence ocular axial length and high myopia.

    Directory of Open Access Journals (Sweden)

    Qiao Fan

    Full Text Available As one of the leading causes of visual impairment and blindness, myopia poses a significant public health burden in Asia. The primary determinant of myopia is an elongated ocular axial length (AL. Here we report a meta-analysis of three genome-wide association studies on AL conducted in 1,860 Chinese adults, 929 Chinese children, and 2,155 Malay adults. We identified a genetic locus on chromosome 1q41 harboring the zinc-finger 11B pseudogene ZC3H11B showing genome-wide significant association with AL variation (rs4373767, β = -0.16 mm per minor allele, P(meta =2.69 × 10(-10. The minor C allele of rs4373767 was also observed to significantly associate with decreased susceptibility to high myopia (per-allele odds ratio (OR =0.75, 95% CI: 0.68-0.84, P(meta =4.38 × 10(-7 in 1,118 highly myopic cases and 5,433 controls. ZC3H11B and two neighboring genes SLC30A10 and LYPLAL1 were expressed in the human neural retina, retinal pigment epithelium, and sclera. In an experimental myopia mouse model, we observed significant alterations to gene and protein expression in the retina and sclera of the unilateral induced myopic eyes for the murine genes ZC3H11A, SLC30A10, and LYPLAL1. This supports the likely role of genetic variants at chromosome 1q41 in influencing AL variation and high myopia.

  9. The High Time Resolution Radio Sky

    Science.gov (United States)

    Thornton, D.

    2013-11-01

    Pulsars are laboratories for extreme physics unachievable on Earth. As individual sources and possible orbital companions can be used to study magnetospheric, emission, and superfluid physics, general relativistic effects, and stellar and binary evolution. As populations they exhibit a wide range of sub-types, with parameters varying by many orders of magnitude signifying fundamental differences in their evolutionary history and potential uses. There are currently around 2200 known pulsars in the Milky Way, the Magellanic clouds, and globular clusters, most of which have been discovered with radio survey observations. These observations, as well as being suitable for detecting the repeating signals from pulsars, are well suited for identifying other transient astronomical radio bursts that last just a few milliseconds that either singular in nature, or rarely repeating. Prior to the work of this thesis non-repeating radio transients at extragalactic distances had possibly been discovered, however with just one example status a real astronomical sources was in doubt. Finding more of these sources was a vital to proving they were real and to open up the universe for millisecond-duration radio astronomy. The High Time Resolution Universe survey uses the multibeam receiver on the 64-m Parkes radio telescope to search the whole visible sky for pulsars and transients. The temporal and spectral resolution of the receiver and the digital back-end enable the detection of relatively faint, and distant radio sources. From the Parkes telescope a large portion of the Galactic plane can be seen, a rich hunting ground for radio pulsars of all types, while previously poorly surveyed regions away from the Galactic plane are also covered. I have made a number of pulsar discoveries in the survey, including some rare systems. These include PSR J1226-6208, a possible double neutron star system in a remarkably circular orbit, PSR J1431-471 which is being eclipsed by its companion with

  10. The effect of variable stator on performance of a highly loaded tandem axial flow compressor stage

    Science.gov (United States)

    Eshraghi, Hamzeh; Boroomand, Masoud; Tousi, Abolghasem M.; Fallah, Mohammad Toude; Mohammadi, Ali

    2016-06-01

    Increasing the aerodynamic load on compressor blades helps to obtain a higher pressure ratio in lower rotational speeds. Considering the high aerodynamic load effects and structural concerns in the design process, it is possible to obtain higher pressure ratios compared to conventional compressors. However, it must be noted that imposing higher aerodynamic loads results in higher loss coefficients and deteriorates the overall performance. To avoid the loss increase, the boundary layer quality must be studied carefully over the blade suction surface. Employment of advanced shaped airfoils (like CDAs), slotted blades or other boundary layer control methods has helped the designers to use higher aerodynamic loads on compressor blades. Tandem cascade is a passive boundary layer control method, which is based on using the flow momentum to control the boundary layer on the suction surface and also to avoid the probable separation caused by higher aerodynamic loads. In fact, the front pressure side flow momentum helps to compensate the positive pressure gradient over the aft blade's suction side. Also, in comparison to the single blade stators, tandem variable stators have more degrees of freedom, and this issue increases the possibility of finding enhanced conditions in the compressor off-design performance. In the current study, a 3D design procedure for an axial flow tandem compressor stage has been applied to design a highly loaded stage. Following, this design is numerically investigated using a CFD code and the stage characteristic map is reported. Also, the effect of various stator stagger angles on the compressor performance and especially on the compressor surge margin has been discussed. To validate the CFD method, another known compressor stage is presented and its performance is numerically investigated and the results are compared with available experimental results.

  11. The Effect of Variable Stator on Performance of a Highly Loaded Tandem Axial Flow Compressor Stage

    Institute of Scientific and Technical Information of China (English)

    Hamzeh Eshraghi; Masoud Boroomand; Abolghasem M.Tousi; Mohammad Toude Fallah; Ali Mohammadi

    2016-01-01

    Increasing the aerodynamic load on compressor blades helps to obtain a higher pressure ratio in lower rotational speeds.Considering the high aerodynamic load effects and structural concerns in the design process,it is possible to obtain higher pressure ratios compared to conventional compressors.However,it must be noted that imposing higher aerodynamic loads results in higher loss coefficients and deteriorates the overall performance.To avoid the loss increase,the boundary layer quality must be studied carefully over the blade suction surface.Employment of advanced shaped airfoils (like CDAs),slotted blades or other boundary layer control methods has helped the designers to use higher aerodynamic loads on compressor blades.Tandem cascade is a passive boundary layer control method,which is based on using the flow momentum to control the boundary layer on the suction surface and also to avoid the probable separation caused by higher aerodynamic loads.In fact,the front pressure side flow momentum helps to compensate the positive pressure gradient over the aft blade's suction side.Also,in comparison to the single blade stators,tandem variable stators have more degrees of freedom,and this issue increases the possibility of finding enhanced conditions in the compressor off-design performance.In the current study,a 3D design procedure for an axial flow tandem compressor stage has been applied to design a highly loaded stage.Following,this design is numerically investigated using a CFD code and the stage characteristic map is reported.Also,the effect of various stator stagger angles on the compressor performance and especially on the compressor surge margin has been discussed.To validate the CFD method,another known compressor stage is presented and its performance is numerically investigated and the results are compared with available experimental results.

  12. AIRBORNE HIGH-RESOLUTION DIGITAL IMAGING SYSTEM

    Directory of Open Access Journals (Sweden)

    Prado-Molina, J.

    2006-04-01

    Full Text Available A low-cost airborne digital imaging system capable to perform aerial surveys with small-format cameras isintroduced. The equipment is intended to obtain high-resolution multispectral digital photographs constituting so aviable alternative to conventional aerial photography and satellite imagery. Monitoring software handles all theprocedures involved in image acquisition, including flight planning, real-time graphics for aircraft position updatingin a mobile map, and supervises the main variables engaged in the imaging process. This software also creates fileswith the geographical position of the central point of every image, and the flight path followed by the aircraftduring the entire survey. The cameras are mounted on a three-axis stabilized platform. A set of inertial sensorsdetermines platform's deviations independently from the aircraft and an automatic control system keeps thecameras at a continuous nadir pointing and heading, with a precision better than ± 1 arc-degree in three-axis. Thecontrol system is also in charge of saving the platform’s orientation angles when the monitoring software triggersthe camera. These external orientation parameters, together with a procedure for camera calibration give theessential elements for image orthocorrection. Orthomosaics are constructed using commercial GIS software.This system demonstrates the feasibility of large area coverage in a practical and economical way using smallformatcameras. Monitoring and automatization reduce the work while increasing the quality and the amount ofuseful images.

  13. High spatial resolution probes for neurobiology applications

    Science.gov (United States)

    Gunning, D. E.; Kenney, C. J.; Litke, A. M.; Mathieson, K.

    2009-06-01

    Position-sensitive biological neural networks, such as the brain and the retina, require position-sensitive detection methods to identify, map and study their behavior. Traditionally, planar microelectrodes have been employed to record the cell's electrical activity with device limitations arising from the electrode's 2-D nature. Described here is the development and characterization of an array of electrically conductive micro-needles aimed at addressing the limitations of planar electrodes. The capability of this array to penetrate neural tissue improves the electrode-cell electrical interface and allows more complicated 3-D networks of neurons, such as those found in brain slices, to be studied. State-of-the-art semiconductor fabrication techniques were used to etch and passivate conformally the metal coat and fill high aspect ratio holes in silicon. These are subsequently transformed into needles with conductive tips. This process has enabled the fabrication of arrays of unprecedented dimensions: 61 hexagonally close-packed electrodes, ˜200 μm tall with 60 μm spacing. Electroplating the tungsten tips with platinum ensure suitable impedance values (˜600 kΩ at 1 kHz) for the recording of neuronal signals. Without compromising spatial resolution of the neuronal recordings, this array adds a new and exciting dimension to the study of biological neural networks.

  14. High Spectral Resolution Lidar (HSRL) Instrument Handbook

    Energy Technology Data Exchange (ETDEWEB)

    Goldsmith, John [Sandia National Lab. (SNL-CA), Livermore, CA (United States)

    2016-04-01

    High Spectral Resolution Lidar (HSRL) systems provide vertical profiles of optical depth, backscatter cross-section, depolarization, and backscatter phase function. All HSRL measurements are absolutely calibrated by reference to molecular scattering, which is measured at each point in the lidar profile. Like the Raman lidar but unlike simple backscatter lidars such as the micropulse lidar, the HSRL can measure backscatter cross-sections and optical depths without prior assumptions about the scattering properties of the atmosphere. The depolarization observations also allow robust discrimination between ice and water clouds. In addition, rigorous error estimates can be computed for all measurements. A very narrow, angular field of view reduces multiple scattering contributions. The small field of view, coupled with a narrow optical bandwidth, nearly eliminates noise due to scattered sunlight. There are two operational U.S. Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) Climate Research Facility HSRL systems, one at the Barrow North Slope of Alaska (NSA) site and the other in the second ARM Mobile Facility (AMF2) collection of instrumentation.

  15. Holographic high-resolution endoscopic image recording

    Science.gov (United States)

    Bjelkhagen, Hans I.

    1991-03-01

    Endoscopic holography or endoholography combines the features of endoscopy and holography. The purpose of endoholographic imaging is to provide the physician with a unique means of extending diagnosis by providing a life-like record of tissue. Endoholographic recording will provide means for microscopic examination of tissue and in some cases may obviate the need to excise specimens for biopsy. In this method holograms which have the unique properties of three-dimensionality large focal depth and high resolution are made with a newly designed endoscope. The endoscope uses a single-mode optical fiber for illumination and single-beam reflection holograms are recorded in close contact with the tissue at the distal end of the endoscope. The holograms are viewed under a microscope. By using the proper combinations of dyes for staining specific tissue types with various wavelengths of laser illumination increased contrast on the cellular level can be obtained. Using dyes such as rose bengal in combination with the 514. 5 nm line of an argon ion laser and trypan blue or methylene blue with the 647. 1 nm line of a krypton ion laser holograms of the stained colon of a dog showed the architecture of the colon''s columnar epithelial cells. It is hoped through chronological study using this method in-vivo an increased understanding of the etiology and pathology of diseases such as Crohn''s diseases colitis proctitis and several different forms of cancer will help

  16. High-resolution imaging using endoscopic holography

    Science.gov (United States)

    Bjelkhagen, Hans I.

    1990-08-01

    Endoscopic holography or endoholography combines the features of endoscopy and holography. The purpose of endoholographic imaging is to provide the physician with a unique means of extending diagnosis by providing a life-like record of tissue. Endoholographic recording will provide means for microscopic examination of tissue and in some cases may obviate the need to excise specimens for biopsy. In this method holograms which have the unique properties of three-dimensionality large focal depth and high resolution are made with a newly designed endoscope. The endoscope uses a single-mode optical fiber for illumination and single-beam reflection holograms are recorded in close contact with the tissue at the distal end of the endoscope. The holograms are viewed under a microscope. By using the proper combinations of dyes for staining specific tissue types with various wavelengths of laser illumination increased contrast on the cellular level can be obtained. Using dyes such as rose bengal in combination with the 514. 5 nm line of an argon ion laser and trypan blue or methylene blue with the 647. 1 nm line of a krypton ion laser holograms of the stained colon of a dog showed the architecture of the colon''s columnar epithelial cells. It is hoped through chronological study using this method in-vivo an increased understanding of the etiology and pathology of diseases such as Crohn''s diseases colitis proctitis and several different forms of cancer will help to their control. 1.

  17. DUACS: Toward High Resolution Sea Level Products

    Science.gov (United States)

    Faugere, Y.; Gerald, D.; Ubelmann, C.; Claire, D.; Pujol, M. I.; Antoine, D.; Desjonqueres, J. D.; Picot, N.

    2016-12-01

    The DUACS system produces, as part of the CNES/SALP project, and the Copernicus Marine Environment and Monitoring Service, high quality multimission altimetry Sea Level products for oceanographic applications, climate forecasting centers, geophysic and biology communities... These products consist in directly usable and easy to manipulate Level 3 (along-track cross-calibrated SLA) and Level 4 products (multiple sensors merged as maps or time series) and are available in global and regional version (Mediterranean Sea, Arctic, European Shelves …).The quality of the products is today limited by the altimeter technology "Low Resolution Mode" (LRM), and the lack of available observations. The launch of 2 new satellites in 2016, Jason-3 and Sentinel-3A, opens new perspectives. Using the global Synthetic Aperture Radar mode (SARM) coverage of S3A and optimizing the LRM altimeter processing (retracking, editing, ...) will allow us to fully exploit the fine-scale content of the altimetric missions. Thanks to this increase of real time altimetry observations we will also be able to improve Level-4 products by combining these new Level-3 products and new mapping methodology, such as dynamic interpolation. Finally these improvements will benefit to downstream products : geostrophic currents, Lagrangian products, eddy atlas… Overcoming all these challenges will provide major upgrades of Sea Level products to better fulfill user needs.

  18. Laser wavelength comparison by high resolution interferometry.

    Science.gov (United States)

    Layer, H P; Deslattes, R D; Schweitzer, W G

    1976-03-01

    High resolution interferometry has been used to determine the wavelength ratio between two molecularly stabilized He-Ne lasers, one locked to a methane absorption at 3.39 microm and the other locked to the k peak of (129)I(2) at 633 nm. An optical beat frequency technique gave fractional orders while a microwave sideband method yielded the integer parts. Conventional (third derivative) peak seeking servoes stabilized both laser and cavity lengths. Reproducibility of the electronic control system and optics was a few parts in 10(12), while systematic errors associated with curvature of the cavity mirrors limited the accuracy of the wavelength ratio measurement to 2 parts in 10(10). The measured wavelength ratio of the methane stabilized He-Ne laser at 3.39 microm [P(7) line, nu(3) band] to the (129)I(2) (k peak) stabilized He-Ne laser at 633 nm was 5.359 049 260 6 (0.000 2 ppm). This ratio agrees with that calculated from the (lower accuracy) results of earlier wavelength measurements made relative to the (86)Kr standard. Its higher accuracy thus permits a provisional extension of the frequency scale based on the cesium oscillator into the visible spectrum.

  19. High-resolution ophthalmic imaging system

    Science.gov (United States)

    Olivier, Scot S.; Carrano, Carmen J.

    2007-12-04

    A system for providing an improved resolution retina image comprising an imaging camera for capturing a retina image and a computer system operatively connected to the imaging camera, the computer producing short exposures of the retina image and providing speckle processing of the short exposures to provide the improved resolution retina image. The system comprises the steps of capturing a retina image, producing short exposures of the retina image, and speckle processing the short exposures of the retina image to provide the improved resolution retina image.

  20. Axial myopathy

    DEFF Research Database (Denmark)

    Witting, Nanna; Andersen, Linda K; Vissing, John

    2016-01-01

    musculature involvement in the majority of myopathies in which paraspinal musculature was examined. Even in diseases named after a certain pattern of non-axial muscle affection, such as facioscapulohumeral and limb girdle muscular dystrophies, affection of the axial musculature was often severe and early...

  1. Development of a highly efficient brushless dc motor utilizing both radial and axial air gaps

    Science.gov (United States)

    Kang, K. J.; Jang, G. H.; Sung, S. J.; Chang, J. H.

    2012-04-01

    This research proposes an effective structure for a brushless dc motor utilizing both radial and axial air gaps. The proposed motor generates torque in both the radial and axial air gaps, while the conventional motor generates torque only in the radial air gap. The proposed motor was optimized to minimize the electromagnetic loss of the motor to increase the effective air gap length and fill-factor of the coil while decreasing the saturation of the core at the same time. The electromagnetic loss was reduced by 35% in comparison with a conventional motor.

  2. Evaporative cooling and coherent axial oscillations of highly charged ions in a penning trap.

    Science.gov (United States)

    Hobein, M; Solders, A; Suhonen, M; Liu, Y; Schuch, R

    2011-01-07

    Externally, in an electron beam ion trap, generated Ar16+ ions were retrapped in a Penning trap and evaporatively cooled in their axial motion. The cooling was observed by a novel extraction technique based on the excitation of a coherent axial oscillation which yields short ion bunches of well-defined energies. The initial temperature of the ion cloud was decreased by a factor of more than 140 within 1 s, while the phase-space density of the coldest extracted ion pulses was increased by a factor of up to about 9.

  3. Narrow CSF space at high convexity and high midline areas in idiopathic normal pressure hydrocephalus detected by axial and coronal MRI

    Energy Technology Data Exchange (ETDEWEB)

    Sasaki, Makoto [Iwate Medical University, Department of Radiology, Morioka (Japan); Honda, Satoshi [St. Luke' s International Hospital, Department of Radiology, Tokyo (Japan); Yuasa, Tatsuhiko; Iwamura, Akihide [Kohnodai Hospital, National Center of Neurology and Psychiatry, Department of Neurology, Ichikawa (Japan); Shibata, Eri [Iwate Medical University, Department of Neuropsychiatry, Morioka (Japan); Ohba, Hideki [Iwate Medical University, Department of Neurology, Morioka (Japan)

    2008-02-15

    The aim of this study was to determine the performance of axial and coronal magnetic resonance imaging (MRI) in detecting the narrowing of the cerebrospinal fluid (CSF) space at the high convexity and high midline areas, which is speculated to be one of the clinical characteristics of idiopathic normal pressure hydrocephalus (iNPH). We retrospectively examined axial and coronal T1-weighted images of 14 iNPH patients and 12 age-matched controls. The narrowness of the CSF space at the high convexity/midline was blindly evaluated by five raters using a continuous confidence rating scale for receiver operating characteristic (ROC) analysis. Axial and coronal imaging accurately determined the presence of the narrow cisterns/sulci at the high convexity/midline and was capable of predicting probable/definite iNPH with a high degree of accuracy. there were also no significant differences in the detection of this finding between the axial and coronal images. Both axial and coronal T1-weighted MRI can detect the narrow CSF space at the high convexity/midline accurately and may therefore facilitate clinicians in choosing a management strategy for iNPH patients. (orig.)

  4. High-Resolution Imaging of Asteroids/Satellites with AO

    Science.gov (United States)

    Merline, William

    2012-02-01

    We propose to make high-resolution observations of asteroids using AO, to measure size, shape, and pole position (spin vectors), and/or to search for satellites. We have demonstrated that AO imaging allows determination of the pole/dimensions in 1 or 2 nights on a single target, rather than the years of observations with lightcurve inversion techniques that only yield poles and axial ratios, not true dimensions. Our new technique (KOALA) combines AO imaging with lightcurve and occultation data for optimum size/shape determinations. We request that LGS be available for faint targets, but using NGS AO, we will measure several large and intermediate asteroids that are favorably placed in spring/summer of 2012 for size/shape/pole. Accurately determining the volume from the often-irregular shape allows us to derive densities to much greater precision in cases where the mass is known, e.g., from the presence of a satellite. We will search several d! ozen asteroids for the presence of satellites, particularly in under-studied populations, particularly NEOs (we have recently achieved the first-ever optical image of an NEO binary [Merline et al. 2008b, IAUC 8977]). Satellites provide a real-life lab for testing collisional models. We will search for satellites around special objects at the request of lightcurve observers, and we will make a search for debris in the vicinity of Pluto, in support of the New Horizons mission. Our shape/size work requires observations over most of a full rotation period (typically several hours).

  5. The High Resolution IRAS Galaxy Atlas

    CERN Document Server

    Cao, Y; Prince, T A; Beichman, C A; Cao, Yu; Terebey, Susan; Prince, Thomas A.; Beichman, Charles A.

    1997-01-01

    An atlas of the Galactic plane (-4.7 deg < b < 4.7 deg) plus the molecular clouds in Orion, Rho Oph, and Taurus-Auriga has been produced at 60 and 100 micron from IRAS data. The Atlas consists of resolution-enhanced coadded images having 1 arcmin -- 2 arcmin resolution as well as coadded images at the native IRAS resolution. The IRAS Galaxy Atlas, together with the DRAO HI line / 21 cm continuum and FCRAO CO (1-0) line Galactic plane surveys, both with similar (approx. 1 arcmin) resolution, provide a powerful venue for studying the interstellar medium, star formation and large scale structure in our Galaxy. This paper documents the production and characteristics of the Atlas.

  6. High resolution fire risk mapping in Italy

    Science.gov (United States)

    Fiorucci, Paolo; Biondi, Guido; Campo, Lorenzo; D'Andrea, Mirko

    2014-05-01

    extinguishing actions, leaving more resources to improve safety in areas at risk. With the availability of fire perimeters mapped over a period spanning from 5 to 10 years, depending by the region, a procedure was defined in order to assess areas at risk with high spatial resolution (900 m2) based on objective criteria by observing past fire events. The availability of fire perimeters combined with a detailed knowledge of topography and land cover allowed to understand which are the main features involved in forest fire occurrences and their behaviour. The seasonality of the fire regime was also considered, partitioning the analysis in two macro season (November- April and May- October). In addition, the total precipitation obtained from the interpolation of 30 years-long time series from 460 raingauges and the average air temperature obtained downscaling 30 years ERA-INTERIM data series were considered. About 48000 fire perimeters which burnt about 5500 km2 were considered in the analysis. The analysis has been carried out at 30 m spatial resolution. Some important considerations relating to climate and the territorial features that characterize the fire regime at national level contribute to better understand the forest fire phenomena. These results allow to define new strategies for forest fire prevention and management extensible to other geographical areas.

  7. Super-Resolution Reconstruction of High-Resolution Satellite ZY-3 TLC Images.

    Science.gov (United States)

    Li, Lin; Wang, Wei; Luo, Heng; Ying, Shen

    2017-05-07

    Super-resolution (SR) image reconstruction is a technique used to recover a high-resolution image using the cumulative information provided by several low-resolution images. With the help of SR techniques, satellite remotely sensed images can be combined to achieve a higher-resolution image, which is especially useful for a two- or three-line camera satellite, e.g., the ZY-3 high-resolution Three Line Camera (TLC) satellite. In this paper, we introduce the application of the SR reconstruction method, including motion estimation and the robust super-resolution technique, to ZY-3 TLC images. The results show that SR reconstruction can significantly improve both the resolution and image quality of ZY-3 TLC images.

  8. Large Scale, High Resolution, Mantle Dynamics Modeling

    Science.gov (United States)

    Geenen, T.; Berg, A. V.; Spakman, W.

    2007-12-01

    To model the geodynamic evolution of plate convergence, subduction and collision and to allow for a connection to various types of observational data, geophysical, geodetical and geological, we developed a 4D (space-time) numerical mantle convection code. The model is based on a spherical 3D Eulerian fem model, with quadratic elements, on top of which we constructed a 3D Lagrangian particle in cell(PIC) method. We use the PIC method to transport material properties and to incorporate a viscoelastic rheology. Since capturing small scale processes associated with localization phenomena require a high resolution, we spend a considerable effort on implementing solvers suitable to solve for models with over 100 million degrees of freedom. We implemented Additive Schwartz type ILU based methods in combination with a Krylov solver, GMRES. However we found that for problems with over 500 thousend degrees of freedom the convergence of the solver degraded severely. This observation is known from the literature [Saad, 2003] and results from the local character of the ILU preconditioner resulting in a poor approximation of the inverse of A for large A. The size of A for which ILU is no longer usable depends on the condition of A and on the amount of fill in allowed for the ILU preconditioner. We found that for our problems with over 5×105 degrees of freedom convergence became to slow to solve the system within an acceptable amount of walltime, one minute, even when allowing for considerable amount of fill in. We also implemented MUMPS and found good scaling results for problems up to 107 degrees of freedom for up to 32 CPU¡¯s. For problems with over 100 million degrees of freedom we implemented Algebraic Multigrid type methods (AMG) from the ML library [Sala, 2006]. Since multigrid methods are most effective for single parameter problems, we rebuild our model to use the SIMPLE method in the Stokes solver [Patankar, 1980]. We present scaling results from these solvers for 3D

  9. High Resolution Pulse Compression Imaging Using Super Resolution FM-Chirp Correlation Method (SCM)

    Science.gov (United States)

    Fujiwara, M.; Okubo, K.; Tagawa, N.

    This study addresses the issue of the super-resolution pulse compression technique (PCT) for ultrasound imaging. Time resolution of multiple ultrasonic echoes using the FM-Chirp PCT is limited by the bandwidth of the sweep-frequency. That is, the resolution depends on the sharpness of auto-correlation function. We propose the Super resolution FM-Chirp correlation Method (SCM) and evaluate its performance. This method is based on the multiple signal classification (MUSIC) algorithm. Our simulations were made for the model assuming multiple signals reflected from some scatterers. We confirmed that SCM detects time delay of complicated reflected signals successfully with high resolution.

  10. High-resolution second-harmonic optical coherence tomography of collagen in rat-tail tendon

    Science.gov (United States)

    Jiang, Yi; Tomov, Ivan V.; Wang, Yimin; Chen, Zhongping

    2005-03-01

    A high-resolution second-harmonic optical coherence tomography (SH-OCT) system is demonstrated using a spectrum broadened femtosecond Ti :sapphire laser. An axial resolution of 4.2μm at the second-harmonic wave center wavelength of 400 nm has been achieved. Because the SH-OCT system uses the second-harmonic generation signals that strongly depend on the orientation, polarization, and local symmetry properties of chiral molecules, this technique provides unique contrast enhancement to conventional optical coherence tomography. The system is applied to image biological tissues of the rat-tail tendon. Highly organized collagen fibrils in the rat-tail tendon can be visualized in recorded images.

  11. Efficacy of High Intensity Exercise on Disease Activity and Cardiovascular Risk in Active Axial Spondyloarthritis: A Randomized Controlled Pilot Study

    OpenAIRE

    Silje Halvorsen Sveaas; Inger Jorid Berg; Sella Aarrestad Provan; Anne Grete Semb; Kåre Birger Hagen; Nina Vøllestad; Camilla Fongen; Inge C Olsen; Annika Michelsen; Thor Ueland; Pål Aukrust; Kvien, Tore K; Hanne Dagfinrud

    2014-01-01

    BACKGROUND: Physical therapy is recommended for the management of axial spondyloarthritis (axSpA) and flexibility exercises have traditionally been the main focus. Cardiovascular (CV) diseases are considered as a major health concern in axSpA and there is strong evidence that endurance and strength exercise protects against CV diseases. Therefore, the aim of this study was to investigate the efficacy of high intensity endurance and strength exercise on disease activity and CV health in patien...

  12. Disturbances in the afflux of aerodynamically highly stressed axial blowers. Stoerungen in der Zustroemung von aerodynamisch hochbelasteten Axialventilatoren

    Energy Technology Data Exchange (ETDEWEB)

    Kosyna, G.; Krasmann, H. (Technische Univ. Braunschweig, Pfleiderer-Inst. fuer Stroemungsmaschinen (Germany))

    1992-08-01

    When installing blowers, it is not always possible to ensure an optimum fluidic afflux, which can thus produce a change in the operating behaviour compared with the design. Using as an example an axial blower blade with small hub ratio and high aerodynamic blade load, under simulated non-rotation symmetrical allflux conditions, it was possible to show that with the examined distrubance configuration no extreme worsening was produced with regard to the achievable pressure increases and efficiencies of the blower stage. (orig.).

  13. Generation of an ultralong pure longitudinal magnetization needle with high axial homogeneity using an azimuthally polarized beam modulated by pure multi-zone plate phase filter

    Science.gov (United States)

    Yan, Weichao; Nie, Zhongquan; Zhang, Xueru; Wang, Yuxiao; Song, Yinglin

    2017-08-01

    Based on the vector diffraction theory and the inverse Faraday effect in the magneto-optic film, light-induced magnetization distributions, for a high numerical aperture focusing configuration with an azimuthally polarized beam modulated by an optimized pure multi-zone plate phase filter, are investigated. By making use of the compeletely destructive interference of its inter circle with the π phase shift between adjacent sub-annuli, and the capability to extend the constructive interference in the propagating direction through its narrow outer annulus modulated by three misplaced helical phases, an ultralong (107λ ) magnetization needle with both transverse super-resolution (0.37λ ) and uniform axial field strength is achieved in the focal region. The perfect magnetization needle and the accessible method give a guide for ultrahigh density magnetic storage, fabricating magnetic lattices for spin wave operation, as well as atomic trapping.

  14. High Resolution Surface Science at Mars

    Science.gov (United States)

    Bailey, Zachary J.; Tamppari, Leslie K.; Lock, Robert E.; Sturm, Erick J.

    2013-01-01

    The proposed mission would place a 2.4 m telescope in orbit around Mars with two focal plane instruments to obtain the highest resolution images and spectral maps of the surface to date (3-10x better than current). This investigation would make major contributions to all of the Mars Program Goals: life, climate, geology and preparation for human presence.

  15. High spatial resolution LWIR hyperspectral sensor

    Science.gov (United States)

    Roberts, Carson B.; Bodkin, Andrew; Daly, James T.; Meola, Joseph

    2015-06-01

    Presented is a new hyperspectral imager design based on multiple slit scanning. This represents an innovation in the classic trade-off between speed and resolution. This LWIR design has been able to produce data-cubes at 3 times the rate of conventional single slit scan devices. The instrument has a built-in radiometric and spectral calibrator.

  16. High-resolution MRI predicts steroid injection response in carpal tunnel syndrome patients

    Energy Technology Data Exchange (ETDEWEB)

    Aoki, Takatoshi; Oki, Hodaka; Kinoshita, Shunsuke; Yamashita, Yoshiko; Takahashi, Hiroyuki; Hayashida, Yoshiko; Korogi, Yukunori [University of Occupational and Environmental Health School of Medicine, Department of Radiology, Kitakyushu (Japan); Oshige, Takahisa; Sakai, Akinori [University of Occupational and Environmental Health School of Medicine, Department of Orthopaedic Surgery, Kitakyushu (Japan); Matsuyama, Atsushi; Hisaoka, Masanori [University of Occupational and Environmental Health School of Medicine, Department of Pathology and Oncology, Kitakyushu (Japan)

    2014-03-15

    To correlate median nerve T2 signal and shape at the carpal tunnel with steroid injection (SI) response in carpal tunnel syndrome (CTS) patients. One hundred and sixty-three CTS wrists of 92 consecutive patients who were scheduled to undergo SI were prospectively evaluated with 3-T magnetic resonance imaging (MRI) and a nerve conduction study. All patients underwent axial high-resolution T2-weighted MRI (in-plane resolution of 0.25 x 0.25 mm). The CTS wrists were classified into three groups according to the nerve T2 signal and the flattening ratio at the hook of hamate level: group 1, high and oval; group 2, high and flat; group 3, low and flat. Clinical response to SI was evaluated at 6 months after injection. One hundred and thirteen of the 163 wrists (69.3 %) responded well to SI. The percentage of improvement was 81.7 % (49/60) in group 1, 69.9 % (51/73) in group 2, and 43.3 % (13/30) in group 3 (P < 0.01). On stepwise logistic regression analysis high-resolution MRI was the only significant independent factor for SI response in CTS patients (P < 0.01). High-resolution MRI correlates well with SI response in CTS patients and seems useful for predicting SI response. (orig.)

  17. High-speed photography of high-resolution moire patterns

    Science.gov (United States)

    Whitworth, Martin B.; Huntley, Jonathan M.; Field, John E.

    1991-04-01

    The techniques of high resolution moire photography and high speed photography have been combined to allow measurement of the in-plane components of a transient displacement field with microsecond time resolution. Specimen gratings are prepared as casts in a thin layer of epoxy resin on the surface of a specimen. These are illuminated with a flash tube and imaged onto a reference grating with a specially modified camera lens, which incorporates a slotted mask in the aperture plane. For specimen gratings of 75 lines mm1, this selects the +1 and -1 order diffracted beams, thus doubling the effective grating frequency to 150 lines mm1. The resulting real-time moire fringes are recorded with a Hadland 792 image converter camera (Imacon) at an inter-frame time of 2-5ts. The images are digitised and an automatic fringe analysis technique based on the 2-D Fourier transform method is used to extract the displacement information. The technique is illustrated by the results of an investigation into the transient deformation of composite disc specimens, impacted with rectangular metal sliders fired from a gas gun.

  18. Development of highly effective cryogenic printed circuit heat exchanger (PCHE) with low axial conduction

    Science.gov (United States)

    Baek, Seungwhan; Kim, Jin-Hyuck; Jeong, Sangkwon; Jung, Jeheon

    2012-07-01

    This paper presents the results of an experimental investigation of the thermal and hydraulic performance of a printed circuit heat exchanger (PCHE) for use in the cryogenic temperature region. Compact PCHEs with multiple corrugated, longitudinal flow microchannels were fabricated using chemical etching and diffusion bonding to evaluate their thermal and hydraulic performance. The testing of the PCHEs was conducted with helium gas at cryogenic temperatures. The pressure drop and thermal effectiveness values obtained from the measured pressures and temperatures are discussed. The thermal performance was predominantly affected by the axial conduction heat transfer in the low Reynolds number ranges of theses experiments. A simple performance calculation model is presented, and the effectiveness calculated from the model is compared with the experimental data. The design of the cryogenic PCHE was then modified to reduce axial conduction losses.

  19. Low-pressure reversible axial fan with straight profile blades and relatively high efficiency

    OpenAIRE

    2012-01-01

    The paper presents the design and operating characteristics of a model of reversible axial fan with only one impeller, whose reversibility is achieved by changing the direction of rotation. The fan is designed for the purpose of providing alternating air circulation in wood dryers in order to reduce the consumption of electricity for the fan and increase energy efficiency of the entire dryer. To satisfy the reversibility of flow, the shape of the blade profile is symmetrical along the l...

  20. Low-pressure reversible axial fan with straight profile blades and relatively high efficiency

    OpenAIRE

    Spasić Živan T.; Milanović Saša M.; Šušteršič Vanja M.; Nikolić Boban D.

    2012-01-01

    The paper presents the design and operating characteristics of a model of reversible axial fan with only one impeller, whose reversibility is achieved by changing the direction of rotation. The fan is designed for the purpose of providing alternating air circulation in wood dryers in order to reduce the consumption of electricity for the fan and increase energy efficiency of the entire dryer. To satisfy the reversibility of flow, the shape of the blade profile is symmetrical along the l...

  1. Evidence of effective axial U (1 ) symmetry restoration at high temperature QCD

    Science.gov (United States)

    Tomiya, A.; Cossu, G.; Aoki, S.; Fukaya, H.; Hashimoto, S.; Kaneko, T.; Noaki, J.; Jlqcd Collaboration

    2017-08-01

    We study the axial U (1 ) symmetry at a finite temperature in two-flavor lattice QCD. Employing the Möbius domain-wall fermions, we generate gauge configurations slightly above the critical temperature Tc with different lattice sizes L =2 - 4 fm . Our action allows frequent topology tunneling while keeping good chiral symmetry close enough to that of overlap fermions. This allows us to recover full chiral symmetry by an overlap/domain-wall reweighting. Above the phase transition, a strong suppression of the low-lying modes is observed in both overlap and domain-wall Dirac spectra. We, however, find a sizable violation of the Ginsparg-Wilson relation in the Möbius domain-wall Dirac eigenmodes, which dominates the signals of the axial U (1 ) symmetry breaking near the chiral limit. We also find that the use of the overlap fermion only in the valence sector is dangerous since it suffers from the artifacts due to partial quenching. Reweighting the Möbius domain-wall fermion determinant to that of the overlap fermion, we observe the axial U(1) breaking to vanish in the chiral limit, which is stable against the changes of the lattice volume and lattice spacing.

  2. Technique for high axial shielding factor performance of large-scale, thin, open-ended, cylindrical Metglas magnetic shields

    CERN Document Server

    Malkowski, S; Hona, B; Mattie, C; Woods, D; Yan, H; Plaster, B; 10.1063/1.3605665

    2011-01-01

    Metglas 2705M is a low-cost commercially-available, high-permeability Cobalt-based magnetic alloy, provided as a 5.08-cm wide and 20.3-$\\mu$m thick ribbon foil. We present an optimized construction technique for single-shell, large-scale (human-size), thin, open-ended cylindrical Metglas magnetic shields. The measured DC axial and transverse magnetic shielding factors of our 0.61-m diameter and 1.83-m long shields in the Earth's magnetic field were 267 and 1500, for material thicknesses of only 122 $\\mu$m (i.e., 6 foil layers). The axial shielding performance of our single-shell Metglas magnetic shields, obtained without the use of magnetic shaking techniques, is comparable to the performance of significantly thicker, multiple-shell, open-ended Metglas magnetic shields in comparable-magnitude, low-frequency applied external fields reported previously in the literature.

  3. Quantum interpolation for high-resolution sensing.

    Science.gov (United States)

    Ajoy, Ashok; Liu, Yi-Xiang; Saha, Kasturi; Marseglia, Luca; Jaskula, Jean-Christophe; Bissbort, Ulf; Cappellaro, Paola

    2017-02-28

    Recent advances in engineering and control of nanoscale quantum sensors have opened new paradigms in precision metrology. Unfortunately, hardware restrictions often limit the sensor performance. In nanoscale magnetic resonance probes, for instance, finite sampling times greatly limit the achievable sensitivity and spectral resolution. Here we introduce a technique for coherent quantum interpolation that can overcome these problems. Using a quantum sensor associated with the nitrogen vacancy center in diamond, we experimentally demonstrate that quantum interpolation can achieve spectroscopy of classical magnetic fields and individual quantum spins with orders of magnitude finer frequency resolution than conventionally possible. Not only is quantum interpolation an enabling technique to extract structural and chemical information from single biomolecules, but it can be directly applied to other quantum systems for superresolution quantum spectroscopy.

  4. High Resolution RPCs for Large TOF Systems

    CERN Document Server

    Ferreira-Marques, R; CERN. Geneva; Carolino, N; Policarpo, Armando; Fonte, P

    1999-01-01

    Here we report on a particular type of RPC that presents above 95% efficiency for minimum ionizing particles and a very sharp time resolution, below 80 ps sigma. Our 9cm2 cells, made with glass and metal electrodes that form accurately spaced gaps of a few hundred micrometers, are operated at atmospheric pressure in non-flammable gases and can be economically produced in large quantities, opening perspectives for the construction of large area timeof flight systems.

  5. Ultra-high resolution electron microscopy

    Science.gov (United States)

    Oxley, Mark P.; Lupini, Andrew R.; Pennycook, Stephen J.

    2017-02-01

    The last two decades have seen dramatic advances in the resolution of the electron microscope brought about by the successful correction of lens aberrations that previously limited resolution for most of its history. We briefly review these advances, the achievement of sub-Ångstrom resolution and the ability to identify individual atoms, their bonding configurations and even their dynamics and diffusion pathways. We then present a review of the basic physics of electron scattering, lens aberrations and their correction, and an approximate imaging theory for thin crystals which provides physical insight into the various different imaging modes. Then we proceed to describe a more exact imaging theory starting from Yoshioka’s formulation and covering full image simulation methods using Bloch waves, the multislice formulation and the frozen phonon/quantum excitation of phonons models. Delocalization of inelastic scattering has become an important limiting factor at atomic resolution. We therefore discuss this issue extensively, showing how the full-width-half-maximum is the appropriate measure for predicting image contrast, but the diameter containing 50% of the excitation is an important measure of the range of the interaction. These two measures can differ by a factor of 5, are not a simple function of binding energy, and full image simulations are required to match to experiment. The Z-dependence of annular dark field images is also discussed extensively, both for single atoms and for crystals, and we show that temporal incoherence must be included accurately if atomic species are to be identified through matching experimental intensities to simulations. Finally we mention a few promising directions for future investigation.

  6. High-quality multi-resolution volume rendering in medicine

    Institute of Scientific and Technical Information of China (English)

    XIE Kai; YANG Jie; LI Xiao-liang

    2007-01-01

    In order to perform a high-quality interactive rendering of large medical data sets on a single off-theshelf PC, a LOD selection algorithm for multi-resolution volume rendering using 3D texture mapping is presented, which uses an adaptive scheme that renders the volume in a region-of-interest at a high resolution and the volume away from this region at lower resolutions. The algorithm is based on several important criteria, and rendering is done adaptively by selecting high-resolution cells close to a center of attention and low-resolution cells away from this area. In addition, our hierarchical level-of-detail representation guarantees consistent interpolation between different resolution levels. Experiments have been applied to a number of large medical data and have produced high quality images at interactive frame rates using standard PC hardware.

  7. Using high-resolution displays for high-resolution cardiac data.

    Science.gov (United States)

    Goodyer, Christopher; Hodrien, John; Wood, Jason; Kohl, Peter; Brodlie, Ken

    2009-07-13

    The ability to perform fast, accurate, high-resolution visualization is fundamental to improving our understanding of anatomical data. As the volumes of data increase from improvements in scanning technology, the methods applied to visualization must evolve. In this paper, we address the interactive display of data from high-resolution magnetic resonance imaging scanning of a rabbit heart and subsequent histological imaging. We describe a visualization environment involving a tiled liquid crystal display panel display wall and associated software, which provides an interactive and intuitive user interface. The oView software is an OpenGL application that is written for the VR Juggler environment. This environment abstracts displays and devices away from the application itself, aiding portability between different systems, from desktop PCs to multi-tiled display walls. Portability between display walls has been demonstrated through its use on walls at the universities of both Leeds and Oxford. We discuss important factors to be considered for interactive two-dimensional display of large three-dimensional datasets, including the use of intuitive input devices and level of detail aspects.

  8. A general method of design of axial and radial shim coils for NMR and MRI magnets

    Energy Technology Data Exchange (ETDEWEB)

    Bobrov, E.S.; Punchard, W.F.B.

    1988-01-01

    The paper describes a general and efficient method of design of axial and radial shim coils to correct field impurities of various harmonic orders in regions of homogeneity of high resolution Nuclear Magnetic Resonance and Magnetic Resonance Imaging magnets.

  9. A new blade element method for calculating the performance of high and intermediate solidity axial flow fans

    Science.gov (United States)

    Borst, H. V.

    1978-01-01

    A method is presented to design and predict the performance of axial flow rotors operating in a duct. The same method is suitable for the design of ducted fans and open propellers. The unified method is based on the blade element approach and the vortex theory for determining the three dimensional effects, so that two dimensional airfoil data can be used for determining the resultant force on each blade element. Resolution of this force in the thrust and torque planes and integration allows the total performance of the rotor, fan or propeller to be predicted. Three different methods of analysis, one based on a momentum flow theory; another on the vortex theory of propellers; and a third based on the theory of ducted fans, agree and reduce cascade airfoil data to single line as a function of the loading and induced angle of attack at values of constant inflow angle. The theory applies for any solidity from .01 to over 1 and any blade section camber. The effects of the duct and blade number can be determined so that the procedure applies over the entire range from two blade open propellers, to ducted helicopter tail rotors, to axial flow compressors with or without guide vanes, and to wind tunnel drive fans.

  10. High resolution RPC's for large TOF systems

    CERN Document Server

    Fonte, Paulo J R; Pinhão, J; Carolino, N; Policarpo, Armando

    2000-01-01

    Here we report on a particular type of RPC that presents up to 99% efficiency for minimum ionizing particles and a very good time resolution, below 50 ps s for the most optimized construction. Our 9 cm2 cells, made with glass and metal electrodes that form accurately spaced gaps of a few hundred micrometers, are operated at atmospheric pressure in non-flammable gases and can be economically produced in large quantities, opening perspectives for the construction of large area time of flight systems.

  11. High resolution IVEM tomography of biological specimens

    Energy Technology Data Exchange (ETDEWEB)

    Sedat, J.W.; Agard, D.A. [Univ. of California, San Francisco, CA (United States)

    1997-02-01

    Electron tomography is a powerful tool for elucidating the three-dimensional architecture of large biological complexes and subcellular organelles. The introduction of intermediate voltage electron microscopes further extended the technique by providing the means to examine very large and non-symmetrical subcellular organelles, at resolutions beyond what would be possible using light microscopy. Recent studies using electron tomography on a variety of cellular organelles and assemblies such as centrosomes, kinetochores, and chromatin have clearly demonstrated the power of this technique for obtaining 3D structural information on non-symmetric cell components. When combined with biochemical and molecular observations, these 3D reconstructions have provided significant new insights into biological function.

  12. DSCOVR High Time Resolution Solar Wind Measurements

    Science.gov (United States)

    Szabo, Adam

    2012-01-01

    The Deep Space Climate Observatory (DSCOVR), previously known as Triana, spacecraft is expected to be launched in late 2014. It will carry a fluxgate magnetometer, Faraday Cup solar wind detector and a top-hat electron electrostatic analyzer. The Faraday Cup will provide an unprecedented 10 vectors/sec time resolution measurement of the solar wind proton and alpha reduced distribution functions. Coupled with the 40 vector/sec vector magnetometer measurements, the identification of specific wave modes in the solar wind will be possible for the first time. The science objectives and data products of the mission will be discussed.

  13. Nanosecond microscopy with a high spectroscopic resolution

    CERN Document Server

    Heinrich, C; Ritsch-Marte, M; Bernet, Stefan; Heinrich, Christoph; Ritsch-Marte, Monika

    2005-01-01

    We demonstrate coherent anti-Stokes Raman scattering (CARS) microscopy in a wide-field setup with nanosecond laser pulse excitation. In contrast to confocal setups, the image of a sample can be recorded with a single pair of excitation pulses. For this purpose the excitation geometry is specially designed in order to satisfy the phase matching condition over the whole sample area. The spectral, temporal and spatial sensitivity of the method is demonstrated by imaging test samples, i.e. oil vesicles in sunflower seeds, on a nanosecond timescale. The method provides snapshot imaging in 3 nanoseconds with a spectral resolution of 25 wavenumbers (cm$^{-1}$).

  14. Achieving sensitive, high-resolution laser spectroscopy at CRIS

    Energy Technology Data Exchange (ETDEWEB)

    Groote, R. P. de [Instituut voor Kern- en Stralingsfysica, KU Leuven (Belgium); Lynch, K. M., E-mail: kara.marie.lynch@cern.ch [EP Department, CERN, ISOLDE (Switzerland); Wilkins, S. G. [The University of Manchester, School of Physics and Astronomy (United Kingdom); Collaboration: the CRIS collaboration

    2017-11-15

    The Collinear Resonance Ionization Spectroscopy (CRIS) experiment, located at the ISOLDE facility, has recently performed high-resolution laser spectroscopy, with linewidths down to 20 MHz. In this article, we present the modifications to the beam line and the newly-installed laser systems that have made sensitive, high-resolution measurements possible. Highlights of recent experimental campaigns are presented.

  15. Towards high resolution data assimilation and ensemble forecasting

    NARCIS (Netherlands)

    Stappers, R.J.J.

    2013-01-01

    Due the increase in computational power of supercomputers the grid resolution of high resolution numerical weather prediction models is now reaching the 1 km scale. As a result, mesoscale processes related to high impact weather (such as deep convection) can now explicitly be resolved by the models.

  16. High-resolution X-ray diffraction studies of multilayers

    DEFF Research Database (Denmark)

    Christensen, Finn Erland; Hornstrup, Allan; Schnopper, H. W.

    1988-01-01

    High-resolution X-ray diffraction studies of the perfection of state-of-the-art multilayers are presented. Data were obtained using a triple-axis perfect-crystal X-ray diffractometer. Measurements reveal large-scale figure errors in the substrate. A high-resolution triple-axis set up is required...

  17. High-Speed Smart Camera with High Resolution

    Directory of Open Access Journals (Sweden)

    J. Dubois

    2007-02-01

    Full Text Available High-speed video cameras are powerful tools for investigating for instance the biomechanics analysis or the movements of mechanical parts in manufacturing processes. In the past years, the use of CMOS sensors instead of CCDs has enabled the development of high-speed video cameras offering digital outputs, readout flexibility, and lower manufacturing costs. In this paper, we propose a high-speed smart camera based on a CMOS sensor with embedded processing. Two types of algorithms have been implemented. A compression algorithm, specific to high-speed imaging constraints, has been implemented. This implementation allows to reduce the large data flow (6.55 Gbps and to propose a transfer on a serial output link (USB 2.0. The second type of algorithm is dedicated to feature extraction such as edge detection, markers extraction, or image analysis, wavelet analysis, and object tracking. These image processing algorithms have been implemented into an FPGA embedded inside the camera. These implementations are low-cost in terms of hardware resources. This FPGA technology allows us to process in real time 500 images per second with a 1280×1024 resolution. This camera system is a reconfigurable platform, other image processing algorithms can be implemented.

  18. High-Speed Smart Camera with High Resolution

    Directory of Open Access Journals (Sweden)

    Mosqueron R

    2007-01-01

    Full Text Available High-speed video cameras are powerful tools for investigating for instance the biomechanics analysis or the movements of mechanical parts in manufacturing processes. In the past years, the use of CMOS sensors instead of CCDs has enabled the development of high-speed video cameras offering digital outputs, readout flexibility, and lower manufacturing costs. In this paper, we propose a high-speed smart camera based on a CMOS sensor with embedded processing. Two types of algorithms have been implemented. A compression algorithm, specific to high-speed imaging constraints, has been implemented. This implementation allows to reduce the large data flow (6.55 Gbps and to propose a transfer on a serial output link (USB 2.0. The second type of algorithm is dedicated to feature extraction such as edge detection, markers extraction, or image analysis, wavelet analysis, and object tracking. These image processing algorithms have been implemented into an FPGA embedded inside the camera. These implementations are low-cost in terms of hardware resources. This FPGA technology allows us to process in real time 500 images per second with a 1280×1024 resolution. This camera system is a reconfigurable platform, other image processing algorithms can be implemented.

  19. AVERAGE GEOMETRICAL FEATURES OF THE ELECTRON WAVE PACKAGES DISTRIBUTION IN METALLIC CONDUCTORS WITH PULSED AXIAL CURRENT OF HIGH DENSITY

    Directory of Open Access Journals (Sweden)

    M. I. Baranov

    2016-11-01

    Full Text Available Purpose. Calculation and experimental determination of average geometrical features of distributing of macroscopic electron wave packages (EWP in round cylindrical metallic conductors with the pulsed axial current of high density. Methodology. Theoretical bases of the electrical engineering, bases of atomic and quantum physics, electrophysics bases of technique of high voltage and high pulsed currents. Results. The results of the conducted calculation and experimental researches are resulted on close determination of average geometrical features of distribution of longitudinal and radial EWP of macroscopic sizes in the indicated conductors. These descriptions are included by the average widths of «hot» and «cold» longitudinal and radial areas of conductor, and also average steps of division into the periods of similar areas. Results of the executed calculations and high temperature experiments for average geometrical features of longitudinal EWP in the zincked steel wire of diameter of 1.6 mm and length of 320 mm with the aperiodic impulse of current of temporal form 9 ms/160 ms and by amplitude 745 A coincide within the limits of 19 %. Originality. First with the use of methods of atomic and quantum physics the features of the stochastic distributing and mean values of basic geometrical sizes are analysed macroscopic longitudinal and radial EWP in round cylindrical metallic conductors with the pulsed axial current of high density. Practical value. Drawing on the got results in practice will allow more reliably to forecast geometrical sizes and places of localization of arising up in the probed metallic conductors with pulsed axial current of high density longitudinal and radial EWP.

  20. High-Resolution Sonars: What Resolution Do We Need for Target Recognition?

    Directory of Open Access Journals (Sweden)

    Pailhas Yan

    2010-01-01

    Full Text Available Target recognition in sonar imagery has long been an active research area in the maritime domain, especially in the mine-counter measure context. Recently it has received even more attention as new sensors with increased resolution have been developed; new threats to critical maritime assets and a new paradigm for target recognition based on autonomous platforms have emerged. With the recent introduction of Synthetic Aperture Sonar systems and high-frequency sonars, sonar resolution has dramatically increased and noise levels decreased. Sonar images are distance images but at high resolution they tend to appear visually as optical images. Traditionally algorithms have been developed specifically for imaging sonars because of their limited resolution and high noise levels. With high-resolution sonars, algorithms developed in the image processing field for natural images become applicable. However, the lack of large datasets has hampered the development of such algorithms. Here we present a fast and realistic sonar simulator enabling development and evaluation of such algorithms.We develop a classifier and then analyse its performances using our simulated synthetic sonar images. Finally, we discuss sensor resolution requirements to achieve effective classification of various targets and demonstrate that with high resolution sonars target highlight analysis is the key for target recognition.

  1. Numerical simulation of high-swirl flow in axial turbine stage

    Directory of Open Access Journals (Sweden)

    Straka Petr

    2016-01-01

    Full Text Available This article deals with numerical modelling of flow in an axial turbine stage with prismatic blades which are not equipped with shroud. In this case flow through a radial gap above and below ends of blades leads to generation of strong secondary vortices which significantly affect an effciency of the stage. The main attention is paid to turbulence modelling. Besides a linear model based on Boussinesq approximation a nonlinear model based on higher order closure formula is used. Also an effect of a curvature correction is taken into account.

  2. Design of a high performance low aerodynamic noise axial flow fan

    OpenAIRE

    2007-01-01

    The project starts with a description of the main sources of noise in an axial flow fan for concluding that the thing we should avoid is the trailing edge noise. After that the formulas for designing a fan and an aerodynamics background are presented. Once we get the results of these formulas a low noise optimization is carried on for leading us to a table of results where the main characteristics of design for our fan are obtained. After these tables the design of the fan is obtained with Pr...

  3. Analysis and Design Considerations of a High-Power Density, Dual Air Gap, Axial-Field Brushless, Permanent Magnet Motor.

    Science.gov (United States)

    Cho, Chahee Peter

    1995-01-01

    Until recently, brush dc motors have been the dominant drive system because they provide easily controlled motor speed over a wide range, rapid acceleration and deceleration, convenient control of position, and lower product cost. Despite these capabilities, the brush dc motor configuration does not satisfy the design requirements for the U.S. Navy's underwater propulsion applications. Technical advances in rare-earth permanent magnet materials, in high-power semiconductor transistor technology, and in various rotor position-sensing devices have made using brushless permanent magnet motors a viable alternative. This research investigates brushless permanent magnet motor technology, studying the merits of dual-air gap, axial -field, brushless, permanent magnet motor configuration in terms of power density, efficiency, and noise/vibration levels. Because the design objectives for underwater motor applications include high-power density, high-performance, and low-noise/vibration, the traditional, simplified equivalent circuit analysis methods to assist in meeting these goals were inadequate. This study presents the development and verification of detailed finite element analysis (FEA) models and lumped parameter circuit models that can calculate back electromotive force waveforms, inductance, cogging torque, energized torque, and eddy current power losses. It is the first thorough quantification of dual air-gap, axial -field, brushless, permanent magnet motor parameters and performance characteristics. The new methodology introduced in this research not only facilitates the design process of an axial field, brushless, permanent magnet motor but reinforces the idea that the high-power density, high-efficiency, and low-noise/vibration motor is attainable.

  4. The high spectral resolution (scanning) lidar (HSRL)

    Energy Technology Data Exchange (ETDEWEB)

    Eloranta, E. [Univ. of Wisconsin, Madison, WI (United States)

    1995-09-01

    Lidars enable the spatial resolution of optical depth variation in clouds. The optical depth must be inverted from the backscatter signal, a process which is complicated by the fact that both molecular and aerosol backscatter signals are present. The HSRL has the advantage of allowing these two signals to be separated. It has a huge dynamic range, allowing optical depth retrieval for t = 0.01 to 3. Depolarization is used to determine the nature of hydrometeors present. Experiments show that water clouds must almost always be taken into account during cirrus observations. An exciting new development is the possibility of measuring effective radius via diffraction peak width and variable field-of-view measurements. 2 figs.

  5. Studying stellar populations at high spectral resolution

    CERN Document Server

    Bruzual, Gustavo A

    2007-01-01

    I describe very briefly the new libraries of empirical spectra of stars covering wide ranges of values of the atmospheric parameters Teff, log g, [Fe/H], as well as spectral type, that have become available in the recent past, among them the HNGSL, MILES, UVES-POP, ELODIE, and the IndoUS libraries. I show the results of using the IndoUS and the HNGSL libraries, as well as an atlas of theoretical model atmospheres, to build population synthesis models. These libraries are complementary in spectral resolution and wavelength coverage, and will prove extremely useful to describe spectral features expected in galaxy spectra from the NUV to the NIR. The fits to observed galaxy spectra using simple and composite stellar population models are discussed.

  6. A high-resolution vehicle emission inventory for China

    Science.gov (United States)

    Zheng, B.; Zhang, Q.; He, K.; Huo, H.; Yao, Z.; Wang, X.

    2012-12-01

    Developing high resolution emission inventory is an essential task for air quality modeling and management. However, current vehicle emission inventories in China are usually developed at provincial level and then allocated to grids based on various spatial surrogates, which is difficult to get high spatial resolution. In this work, we developed a new approach to construct a high-resolution vehicle emission inventory for China. First, vehicle population at county level were estimated by using the relationship between per-capita GDP and vehicle ownership. Then the Weather Research and Forecasting (WRF) model were used to drive the International Vehicle Emission (IVE) model to get monthly emission factors for each county. Finally, vehicle emissions by county were allocated to grids with 5-km horizon resolution by using high-resolution road network data. This work provides a better understanding of spatial representation of vehicle emissions in China and can benefit both air quality modeling and management with improved spatial accuracy.

  7. Towards optical intensity interferometry for high angular resolution stellar astrophysics

    CERN Document Server

    Nunez, Paul D

    2012-01-01

    Most neighboring stars are still detected as point sources and are beyond the angular resolution reach of current observatories. Methods to improve our understanding of stars at high angular resolution are investigated. Air Cherenkov telescopes (ACTs), primarily used for Gamma-ray astronomy, enable us to increase our understanding of the circumstellar environment of a particular system. When used as optical intensity interferometers, future ACT arrays will allow us to detect stars as extended objects and image their surfaces at high angular resolution. Optical stellar intensity interferometry (SII) with ACT arrays, composed of nearly 100 telescopes, will provide means to measure fundamental stellar parameters and also open the possibility of model-independent imaging. A data analysis algorithm is developed and permits the reconstruction of high angular resolution images from simulated SII data. The capabilities and limitations of future ACT arrays used for high angular resolution imaging are investigated via ...

  8. Research Relative to High Spatial Resolution Passive Microwave Sounding Systems

    Science.gov (United States)

    Staelin, D. H.; Rosenkranz, P. W.

    1984-01-01

    Methods to obtain high resolution passive microwave weather observations, and understanding of their probable impact on numerical weather prediction accuracy were investigated. The development of synthetic aperture concepts for geosynchronous passive microwave sounders were studied. The effects of clouds, precipitation, surface phenomena, and atmospheric thermal fine structure on a scale of several kilometers were examined. High resolution passive microwave sounders (e.g., AMSU) with an increased number of channels will produce initialization data for numerical weather prediction (NWP) models with both increased spatial resolution and coverage. The development of statistical models for error growth in high resolution primitive equation NWP models which permit the consequences of various observing system alternatives, including sensors and assimilation times and procedures is discussed. A high resolution three dimensional primitive equation NWP model to determine parameters in an error growth model similar to that formulated by Lorenz, but with more degrees of freedom is utilized.

  9. High-speed, high-resolution Fourier-domain optical coherence tomography system for retinal imaging in the 1060 nm wavelength region.

    Science.gov (United States)

    Puvanathasan, Prabakar; Forbes, Peter; Ren, Zhao; Malchow, Doug; Boyd, Shelley; Bizheva, Kostadinka

    2008-11-01

    A high-speed (47,000 A-scans/s), ultrahigh axial resolution Fourier domain optical coherence tomography (OCT) system for retinal imaging at approximately 1060 nm, based on a 1024 pixel linear array, 47 kHz readout rate InGaAs camera is presented. When interfaced with a custom superluminescent diode (lambda(c) = 1020 nm, Deltalambda = 108 nm, Pout = 9 mW), the system provides 3.3 microm axial OCT resolution at the surface of biological tissue, approximately 4.5 microm in vivo in rat retina, approximately 5.7 microm in vivo in human retina, and 110 dB sensitivity for 870 microW incident power and 21 mus integration time. Retinal tomograms acquired in vivo from a human volunteer and a rat animal model show clear visualization of all intraretinal layer and increased penetration into the choroid.

  10. Whole-animal imaging with high spatio-temporal resolution

    Science.gov (United States)

    Chhetri, Raghav; Amat, Fernando; Wan, Yinan; Höckendorf, Burkhard; Lemon, William C.; Keller, Philipp J.

    2016-03-01

    We developed isotropic multiview (IsoView) light-sheet microscopy in order to image fast cellular dynamics, such as cell movements in an entire developing embryo or neuronal activity throughput an entire brain or nervous system, with high resolution in all dimensions, high imaging speeds, good physical coverage and low photo-damage. To achieve high temporal resolution and high spatial resolution at the same time, IsoView microscopy rapidly images large specimens via simultaneous light-sheet illumination and fluorescence detection along four orthogonal directions. In a post-processing step, these four views are then combined by means of high-throughput multiview deconvolution to yield images with a system resolution of ≤ 450 nm in all three dimensions. Using IsoView microscopy, we performed whole-animal functional imaging of Drosophila embryos and larvae at a spatial resolution of 1.1-2.5 μm and at a temporal resolution of 2 Hz for up to 9 hours. We also performed whole-brain functional imaging in larval zebrafish and multicolor imaging of fast cellular dynamics across entire, gastrulating Drosophila embryos with isotropic, sub-cellular resolution. Compared with conventional (spatially anisotropic) light-sheet microscopy, IsoView microscopy improves spatial resolution at least sevenfold and decreases resolution anisotropy at least threefold. Compared with existing high-resolution light-sheet techniques, such as lattice lightsheet microscopy or diSPIM, IsoView microscopy effectively doubles the penetration depth and provides subsecond temporal resolution for specimens 400-fold larger than could previously be imaged.

  11. Axial Halbach Magnetic Bearings

    Science.gov (United States)

    Eichenberg, Dennis J.; Gallo, Christopher A.; Thompson, William K.

    2008-01-01

    Axial Halbach magnetic bearings have been investigated as part of an effort to develop increasingly reliable noncontact bearings for future high-speed rotary machines that may be used in such applications as aircraft, industrial, and land-vehicle power systems and in some medical and scientific instrumentation systems. Axial Halbach magnetic bearings are passive in the sense that unlike most other magnetic bearings that have been developed in recent years, they effect stable magnetic levitation without need for complex active control.

  12. High resolution resonant recombination measurements using evaporative cooling technique

    Energy Technology Data Exchange (ETDEWEB)

    Beilmann, C; Lopez-Urrutia, J R Crespo; Mokler, P H; Ullrich, J, E-mail: christian.beilmann@mpi-hd.mpg.d [Max-Planck-Institut fuer Kernphysik, Saupfercheckweg 1, 69117 Heidelberg (Germany)

    2010-09-15

    We report on a method significantly improving the energy resolution of dielectronic recombination (DR) measurements in electron beam ion traps (EBITs). The line width of DR resonances can be reduced to values distinctly smaller than the corresponding space charge width of the uncompensated electron beam. The experimental technique based on forced evaporative cooling is presented together with test measurements demonstrating its high efficiency. The principle for resolution improvement is elucidated and the limiting factors are discussed. This method opens access to high resolution DR measurements at high ion-electron collision energies required for innermost shell DR in highly charged ions (HCI).

  13. Cheetah: A high frame rate, high resolution SWIR image camera

    Science.gov (United States)

    Neys, Joel; Bentell, Jonas; O'Grady, Matt; Vermeiren, Jan; Colin, Thierry; Hooylaerts, Peter; Grietens, Bob

    2008-10-01

    A high resolution, high frame rate InGaAs based image sensor and associated camera has been developed. The sensor and the camera are capable of recording and delivering more than 1700 full 640x512pixel frames per second. The FPA utilizes a low lag CTIA current integrator in each pixel, enabling integration times shorter than one microsecond. On-chip logics allows for four different sub windows to be read out simultaneously at even higher rates. The spectral sensitivity of the FPA is situated in the SWIR range [0.9-1.7 μm] and can be further extended into the Visible and NIR range. The Cheetah camera has max 16 GB of on-board memory to store the acquired images and transfer the data over a Gigabit Ethernet connection to the PC. The camera is also equipped with a full CameralinkTM interface to directly stream the data to a frame grabber or dedicated image processing unit. The Cheetah camera is completely under software control.

  14. A high-resolution time-to-digital converter using a three-level resolution

    Science.gov (United States)

    Dehghani, Asma; Saneei, Mohsen; Mahani, Ali

    2016-08-01

    In this article, a three-level resolution Vernier delay line time-to-digital converter (TDC) was proposed. The proposed TDC core was based on the pseudo-differential digital architecture that made it insensitive to nMOS and pMOS transistor mismatches. It also employed a Vernier delay line (VDL) in conjunction with an asynchronous read-out circuitry. The time interval resolution was equal to the difference of delay between buffers of upper and lower chains. Then, via the extra chain included in the lower delay line, resolution was controlled and power consumption was reduced. This method led to high resolution and low power consumption. The measurement results of TDC showed a resolution of 4.5 ps, 12-bit output dynamic range, and integral nonlinearity of 1.5 least significant bits. This TDC achieved the consumption of 68.43 µW from 1.1-V supply.

  15. Updating Maps Using High Resolution Satellite Imagery

    Science.gov (United States)

    Alrajhi, Muhamad; Shahzad Janjua, Khurram; Afroz Khan, Mohammad; Alobeid, Abdalla

    2016-06-01

    Kingdom of Saudi Arabia is one of the most dynamic countries of the world. We have witnessed a very rapid urban development's which are altering Kingdom's landscape on daily basis. In recent years a substantial increase in urban populations is observed which results in the formation of large cities. Considering this fast paced growth, it has become necessary to monitor these changes, in consideration with challenges faced by aerial photography projects. It has been observed that data obtained through aerial photography has a lifecycle of 5-years because of delay caused by extreme weather conditions and dust storms which acts as hindrances or barriers during aerial imagery acquisition, which has increased the costs of aerial survey projects. All of these circumstances require that we must consider some alternatives that can provide us easy and better ways of image acquisition in short span of time for achieving reliable accuracy and cost effectiveness. The approach of this study is to conduct an extensive comparison between different resolutions of data sets which include: Orthophoto of (10 cm) GSD, Stereo images of (50 cm) GSD and Stereo images of (1 m) GSD, for map updating. Different approaches have been applied for digitizing buildings, roads, tracks, airport, roof level changes, filling stations, buildings under construction, property boundaries, mosques buildings and parking places.

  16. Sunspot Group Development in High Resolution

    CERN Document Server

    Muraközy, J; Ludmány, A

    2014-01-01

    The Solar and Heliospheric Obseratory/Michelson Doppler Imager--Debrecen Data (SDD) sunspot catalogue provides an opportunity to study the details and development of sunspot groups on a large statistical sample. The SDD data allow, in particular, the differential study of the leading and following parts with a temporal resolution of 1.5 hours. In this study, we analyse the equilibrium distance of sunspot groups as well as the evolution of this distance over the lifetime of the groups and the shifts in longitude associated with these groups. We also study the asymmetry between the compactness of the leading and following parts, as well as the time-profiles for the development of the area of sunspot groups. A logarithmic relationship has been found between the total area and the distance of leading-following parts of active regions (ARs) at the time of their maximum area. In the developing phase the leading part moves forward; this is more noticeable in larger ARs. The leading part has a higher growth rate than...

  17. Wide-field, high-resolution Fourier ptychographic microscopy

    CERN Document Server

    Zheng, Guoan; Yang, Changhuei

    2014-01-01

    In this article, we report an imaging method, termed Fourier ptychographic microscopy (FPM), which iteratively stitches together a number of variably illuminated, low-resolution intensity images in Fourier space to produce a wide-field, high-resolution complex sample image. By adopting a wavefront correction strategy, the FPM method can also correct for aberrations and digitally extend a microscope's depth-of-focus beyond the physical limitations of its optics. As a demonstration, we built a microscope prototype with a resolution of 0.78 um, a field-of-view of ~120 mm2, and a resolution-invariant depth-of-focus of 0.3 mm (characterized at 632 nm). Gigapixel colour images of histology slides verify FPM's successful operation. The reported imaging procedure transforms the general challenge of high-throughput, high-resolution microscopy from one that is coupled to the physical limitations of the system's optics to one that is solvable through computation.

  18. High resolution mid-infrared spectroscopy based on frequency upconversion

    DEFF Research Database (Denmark)

    Dam, Jeppe Seidelin; Hu, Qi; Tidemand-Lichtenberg, Peter

    2013-01-01

    We present high resolution upconversion of incoherent infrared radiation by means of sum-frequency mixing with a laser followed by simple CCD Si-camera detection. Noise associated with upconversion is, in strong contrast to room temperature direct mid-IR detection, extremely small, thus very faint...... signals can be analyzed. The obtainable frequency resolution is usually in the nm range where sub nm resolution is preferred in many applications, like gas spectroscopy. In this work we demonstrate how to obtain sub nm resolution when using upconversion. In the presented realization one object point...

  19. Achieving High Resolution Timer Events in Virtualized Environment.

    Science.gov (United States)

    Adamczyk, Blazej; Chydzinski, Andrzej

    2015-01-01

    Virtual Machine Monitors (VMM) have become popular in different application areas. Some applications may require to generate the timer events with high resolution and precision. This however may be challenging due to the complexity of VMMs. In this paper we focus on the timer functionality provided by five different VMMs-Xen, KVM, Qemu, VirtualBox and VMWare. Firstly, we evaluate resolutions and precisions of their timer events. Apparently, provided resolutions and precisions are far too low for some applications (e.g. networking applications with the quality of service). Then, using Xen virtualization we demonstrate the improved timer design that greatly enhances both the resolution and precision of achieved timer events.

  20. High-resolution spectroscopy of gases for industrial applications

    DEFF Research Database (Denmark)

    Fateev, Alexander; Clausen, Sønnik

    High-resolution spectroscopy of gases is a powerful technique which has various fundamental and practical applications: in situ simultaneous measurements of gas temperature and gas composition, radiative transfer modeling, validation of existing and developing of new databases and etc. Existing...... to, for example, atmospheric research, combustion and gasification. Some high-temperature, high-resolution IR/UV absorption/transmission measurements gases (e.g. CO2, SO2, SO3 and phenol) are presented....

  1. Ultra-high resolution and high-brightness AMOLED

    Science.gov (United States)

    Wacyk, Ihor; Ghosh, Amal; Prache, Olivier; Draper, Russ; Fellowes, Dave

    2012-06-01

    As part of its continuing effort to improve both the resolution and optical performance of AMOLED microdisplays, eMagin has recently developed an SXGA (1280×3×1024) microdisplay under a US Army RDECOM CERDEC NVESD contract that combines the world's smallest OLED pixel pitch with an ultra-high brightness green OLED emitter. This development is aimed at next-generation HMD systems with "see-through" and daylight imaging requirements. The OLED pixel array is built on a 0.18-micron CMOS backplane and contains over 4 million individually addressable pixels with a pixel pitch of 2.7 × 8.1 microns, resulting in an active area of 0.52 inches diagonal. Using both spatial and temporal enhancement, the display can provide over 10-bits of gray-level control for high dynamic range applications. The new pixel design also enables the future implementation of a full-color QSXGA (2560 × RGB × 2048) microdisplay in an active area of only 1.05 inch diagonal. A low-power serialized low-voltage-differential-signaling (LVDS) interface is integrated into the display for use as a remote video link for tethered systems. The new SXGA backplane has been combined with the high-brightness green OLED device developed by eMagin under an NVESD contract. This OLED device has produced an output brightness of more than 8000fL with all pixels on; lifetime measurements are currently underway and will presented at the meeting. This paper will describe the operational features and first optical and electrical test results of the new SXGA demonstrator microdisplay.

  2. Spatially adaptive regularized iterative high-resolution image reconstruction algorithm

    Science.gov (United States)

    Lim, Won Bae; Park, Min K.; Kang, Moon Gi

    2000-12-01

    High resolution images are often required in applications such as remote sensing, frame freeze in video, military and medical imaging. Digital image sensor arrays, which are used for image acquisition in many imaging systems, are not dense enough to prevent aliasing, so the acquired images will be degraded by aliasing effects. To prevent aliasing without loss of resolution, a dense detector array is required. But it may be very costly or unavailable, thus, many imaging systems are designed to allow some level of aliasing during image acquisition. The purpose of our work is to reconstruct an unaliased high resolution image from the acquired aliased image sequence. In this paper, we propose a spatially adaptive regularized iterative high resolution image reconstruction algorithm for blurred, noisy and down-sampled image sequences. The proposed approach is based on a Constrained Least Squares (CLS) high resolution reconstruction algorithm, with spatially adaptive regularization operators and parameters. These regularization terms are shown to improve the reconstructed image quality by forcing smoothness, while preserving edges in the reconstructed high resolution image. Accurate sub-pixel motion registration is the key of the success of the high resolution image reconstruction algorithm. However, sub-pixel motion registration may have some level of registration error. Therefore, a reconstruction algorithm which is robust against the registration error is required. The registration algorithm uses a gradient based sub-pixel motion estimator which provides shift information for each of the recorded frames. The proposed algorithm is based on a technique of high resolution image reconstruction, and it solves spatially adaptive regularized constrained least square minimization functionals. In this paper, we show that the reconstruction algorithm gives dramatic improvements in the resolution of the reconstructed image and is effective in handling the aliased information. The

  3. Sensitivity study of reliable, high-throughput resolution metricsfor photoresists

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Christopher N.; Naulleau, Patrick P.

    2007-07-30

    The resolution of chemically amplified resists is becoming an increasing concern, especially for lithography in the extreme ultraviolet (EUV) regime. Large-scale screening and performance-based down-selection is currently underway to identify resist platforms that can support shrinking feature sizes. Resist screening efforts, however, are hampered by the absence of reliable resolution metrics that can objectively quantify resist resolution in a high-throughput fashion. Here we examine two high-throughput metrics for resist resolution determination. After summarizing their details and justifying their utility, we characterize the sensitivity of both metrics to two of the main experimental uncertainties associated with lithographic exposure tools, namely: limited focus control and limited knowledge of optical aberrations. For an implementation at EUV wavelengths, we report aberration and focus limited error bars in extracted resolution of {approx} 1.25 nm RMS for both metrics making them attractive candidates for future screening and down-selection efforts.

  4. Depth of interaction resolution measurements for a high resolution PET detector using position sensitive avalanche photodiodes.

    Science.gov (United States)

    Yang, Yongfeng; Dokhale, Purushottam A; Silverman, Robert W; Shah, Kanai S; McClish, Mickel A; Farrell, Richard; Entine, Gerald; Cherry, Simon R

    2006-05-07

    We explore dual-ended read out of LSO arrays with two position sensitive avalanche photodiodes (PSAPDs) as a high resolution, high efficiency depth-encoding detector for PET applications. Flood histograms, energy resolution and depth of interaction (DOI) resolution were measured for unpolished LSO arrays with individual crystal sizes of 1.0, 1.3 and 1.5 mm, and for a polished LSO array with 1.3 mm pixels. The thickness of the crystal arrays was 20 mm. Good flood histograms were obtained for all four arrays, and crystals in all four arrays can be clearly resolved. Although the amplitude of each PSAPD signal decreases as the interaction depth moves further from the PSAPD, the sum of the two PSAPD signals is essentially constant with irradiation depth for all four arrays. The energy resolutions were similar for all four arrays, ranging from 14.7% to 15.4%. A DOI resolution of 3-4 mm (including the width of the irradiation band which is approximately 2 mm) was obtained for all the unpolished arrays. The best DOI resolution was achieved with the unpolished 1 mm array (average 3.5 mm). The DOI resolution for the 1.3 mm and 1.5 mm unpolished arrays was 3.7 and 4.0 mm respectively. For the polished array, the DOI resolution was only 16.5 mm. Summing the DOI profiles across all crystals for the 1 mm array only degraded the DOI resolution from 3.5 mm to 3.9 mm, indicating that it may not be necessary to calibrate the DOI response separately for each crystal within an array. The DOI response of individual crystals in the array confirms this finding. These results provide a detailed characterization of the DOI response of these PSAPD-based PET detectors which will be important in the design and calibration of a PET scanner making use of this detector approach.

  5. Axial and transverse stress-strain characterization of the EU dipole high current density Nb{sub 3}Sn strand

    Energy Technology Data Exchange (ETDEWEB)

    Nijhuis, A; Ilyin, Y; Abbas, W [Faculty of Science and Technology, Low Temperature Division, University of Twente, PO Box 217, 7500 AE Enschede (Netherlands)], E-mail: a.nijhuis@tnw.utwente.nl

    2008-06-15

    We have measured the critical current (I{sub c}) of a high current density Nb{sub 3}Sn strand subjected to spatial periodic bending, periodic contact stress and uniaxial strain. The strand is destined for the cable-in-conduit conductors (CICC) of the European dipole (EDIPO) 12.5 T superconducting magnet test facility. The spatial periodic bending was applied on the strand, using the bending wavelengths from 5 to 10 mm with a peak bending strain of 1.5%, a periodic contact stress with a periodicity of 4.7 mm and a stress level exceeding 250 MPa. For the uniaxial strain characterization, the voltage-current characteristics were measured with an applied axial strain from -0.9% to +0.3%, with a magnetic field from 6 to 14 T, temperature from 4.2 to 10 K and currents up to almost 900 A. In addition the axial stiffness was determined by a tensile axial stress-strain test. The characterization of the strand is essential for understanding the behaviour of the strand under mainly axial thermal stress variation during cool down and transverse electromagnetic forces during charging, which is essential for the design of the CICC for the dipole magnet. The strand appears to be fully reversible in the compressive regime during the axial strain testing, while in the tensile regime, the behaviour is already irreversibly degraded when reaching the maximum in the critical current versus strain characteristic. The degradation is accentuated by an immediate decrease of the n value by a factor of 2. The parameters for the improved deviatoric strain description are derived from the I{sub c} data, giving the accuracy of the scaling with a standard deviation of 4 A, which is by far within the expected deviation for the large scale strand production of such a high J{sub c} strand. The I{sub c} versus the applied bending strain follows the low resistivity limit, indicative of full interfilament current transfer, while a strong decrease is observed at a peak bending strain of {approx}0

  6. High Resolution CryoFESEM of Microbial Surfaces

    Science.gov (United States)

    Erlandsen, Stanley; Lei, Ming; Martin-Lacave, Ines; Dunny, Gary; Wells, Carol

    2003-08-01

    The outer surfaces of three microorganisms, Giardia lamblia, Enterococcus faecalis, and Proteus mirabilis, were investigated by cryo-immobilization followed by sublimation of extracellular ice and cryocoating with either Pt alone or Pt plus carbon. Cryocoated samples were examined at [minus sign]125°C in either an in-lens field emission SEM or a below-the-lens field emission SEM. Cryocoating with Pt alone was sufficient for low magnification observation, but attempts to do high-resolution imaging resulted in radiolysis and cracking of the specimen surface. Double coating with Pt and carbon, in combination with high resolution backscatter electron detectors, enabled high-resolution imaging of the glycocalyx of bacteria, revealing a sponge-like network over the surface. High resolution examination of bacterial flagella also revealed a periodic substructure. Common artifacts included radiolysis leading to “cracking” of the surface, and insufficient deposition of Pt resulting in the absence of detectable surface topography.

  7. High Resolution Orthoimagery = Orthorectified Metro Areas: 2000 - Present

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — High resolution orthorectified images combine the image characteristics of an aerial photograph with the geometric qualities of a map. An orthoimage is a...

  8. High-resolution SPECT for small-animal imaging

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    This article presents a brief overview of the development of high-resolution SPECT for small-animal imaging. A pinhole collimator has been used for high-resolution animal SPECT to provide better spatial resolution and detection efficiency in comparison with a parallel-hole collimator. The theory of imaging characteristics of the pinhole collimator is presented and the designs of the pinhole aperture are discussed. The detector technologies used for the development of small-animal SPECT and the recent advances are presented. The evolving trend of small-animal SPECT is toward a multi-pinhole and a multi-detector system to obtain a high resolution and also a high detection efficiency.

  9. Methodology of high-resolution photography for mural condition database

    Science.gov (United States)

    Higuchi, R.; Suzuki, T.; Shibata, M.; Taniguchi, Y.

    2015-08-01

    Digital documentation is one of the most useful techniques to record the condition of cultural heritage. Recently, high-resolution images become increasingly useful because it is possible to show general views of mural paintings and also detailed mural conditions in a single image. As mural paintings are damaged by environmental stresses, it is necessary to record the details of painting condition on high-resolution base maps. Unfortunately, the cost of high-resolution photography and the difficulty of operating its instruments and software have commonly been an impediment for researchers and conservators. However, the recent development of graphic software makes its operation simpler and less expensive. In this paper, we suggest a new approach to make digital heritage inventories without special instruments, based on our recent our research project in Üzümlü church in Cappadocia, Turkey. This method enables us to achieve a high-resolution image database with low costs, short time, and limited human resources.

  10. High Resolution Screening of biologically active compounds and metabolites

    NARCIS (Netherlands)

    Kool, J.

    2007-01-01

    High Resolution Screening of biologically active compounds and metabolites Jeroen Kool Biotransformation enzymes play a crucial role in the metabolism of both endogenous compounds and xenobiotics. Usually, the detoxication of these compounds by biotransformation enzymes results in harmless metab

  11. NOAA High-Resolution Sea Surface Temperature (SST) Analysis Products

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This archive covers two high resolution sea surface temperature (SST) analysis products developed using an optimum interpolation (OI) technique. The analyses have a...

  12. High Resolution, Range/Range-Rate Imager Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Visidyne proposes to develop a design for a small, lightweight, high resolution, in x, y, and z Doppler imager to assist in the guidance, navigation and control...

  13. Using High Spatial Resolution Digital Imagery

    Science.gov (United States)

    2005-02-01

    frame and a bright area (hot spot) at the center. The same brightness shifts are present within most aerial photography , particularly the pronounced hot...the deciduous trees and shrubs were without leaves. In addition, the reed and grass species were fully senesced . The lack of photosynthetically...For example, high quality, large-scale aerial photography will provide adequate clarity and detail to accurately identify surface features that are

  14. High resolution survey for topographic surveying

    Science.gov (United States)

    Luh, L. C.; Setan, H.; Majid, Z.; Chong, A. K.; Tan, Z.

    2014-02-01

    In this decade, terrestrial laser scanner (TLS) is getting popular in many fields such as reconstruction, monitoring, surveying, as-built of facilities, archaeology, and topographic surveying. This is due the high speed in data collection which is about 50,000 to 1,000,000 three-dimensional (3D) points per second at high accuracy. The main advantage of 3D representation for the data is that it is more approximate to the real world. Therefore, the aim of this paper is to show the use of High-Definition Surveying (HDS), also known as 3D laser scanning for topographic survey. This research investigates the effectiveness of using terrestrial laser scanning system for topographic survey by carrying out field test in Universiti Teknologi Malaysia (UTM), Skudai, Johor. The 3D laser scanner used in this study is a Leica ScanStation C10. Data acquisition was carried out by applying the traversing method. In this study, the result for the topographic survey is under 1st class survey. At the completion of this study, a standard of procedure was proposed for topographic data acquisition using laser scanning systems. This proposed procedure serves as a guideline for users who wish to utilize laser scanning system in topographic survey fully.

  15. Developing Visual Editors for High-Resolution Haptic Patterns

    DEFF Research Database (Denmark)

    Cuartielles, David; Göransson, Andreas; Olsson, Tony

    2012-01-01

    In this article we give an overview of our iterative work in developing visual editors for creating high resolution haptic patterns to be used in wearable, haptic feedback devices. During the past four years we have found the need to address the question of how to represent, construct and edit high...... resolution haptic patterns so that they translate naturally to the user’s haptic experience. To solve this question we have developed and tested several visual editors...

  16. High resolution computed tomography for peripheral facial nerve paralysis

    Energy Technology Data Exchange (ETDEWEB)

    Koester, O.; Straehler-Pohl, H.J.

    1987-01-01

    High resolution computer tomographic examinations of the petrous bones were performed on 19 patients with confirmed peripheral facial nerve paralysis. High resolution CT provides accurate information regarding the extent, and usually regarding the type, of pathological process; this can be accurately localised with a view to possible surgical treatments. The examination also differentiates this from idiopathic paresis, which showed no radiological changes. Destruction of the petrous bone, without facial nerve symptoms, makes early suitable treatment mandatory.

  17. Geometric calibration of high-resolution remote sensing sensors

    Institute of Scientific and Technical Information of China (English)

    LIANG Hong-you; GU Xing-fa; TAO Yu; QIAO Chao-fei

    2007-01-01

    This paper introduces the applications of high-resolution remote sensing imagery and the necessity of geometric calibration for remote sensing sensors considering assurance of the geometric accuracy of remote sensing imagery. Then the paper analyzes the general methodology of geometric calibration. Taking the DMC sensor geometric calibration as an example, the paper discusses the whole calibration procedure. Finally, it gave some concluding remarks on geometric calibration of high-resolution remote sensing sensors.

  18. Scalable Algorithms for Large High-Resolution Terrain Data

    DEFF Research Database (Denmark)

    Mølhave, Thomas; Agarwal, Pankaj K.; Arge, Lars Allan

    2010-01-01

    In this paper we demonstrate that the technology required to perform typical GIS computations on very large high-resolution terrain models has matured enough to be ready for use by practitioners. We also demonstrate the impact that high-resolution data has on common problems. To our knowledge, some...... of the computations we present have never before been carried out by standard desktop computers on data sets of comparable size....

  19. Dynamics of High-Resolution Networks

    DEFF Research Database (Denmark)

    Sekara, Vedran

    NETWORKS are everywhere. From the smallest confines of the cells within our bodies to the webs of social relations across the globe. Networks are not static, they constantly change, adapt, and evolve to suit new conditions. In order to understand the fundamental laws that govern networks we need...... the unprecedented amounts of information collected by mobile phones to gain detailed insight into the dynamics of social systems. This dissertation presents an unparalleled data collection campaign, collecting highly detailed traces for approximately 1000 people over the course of multiple years. The availability...

  20. High-resolution noise radar using slow ADC

    Science.gov (United States)

    Lukin, Konstantin; Vyplavin, Pavlo; Zemlyanyi, Oleg; Lukin, Sergiy; Palamarchuk, Volodymyr

    2011-06-01

    Conventional digital signal processing scheme in noise radars has some limitations related to combination of high resolution and high dynamic range. Those limitations are caused by a tradeoff in performance of currently available ADCs: the faster is ADC the smaller is its depth (number of bits) available. Depth of the ADC determines relation between the smallest and highest observable signals and thus limits its dynamic range. In noise radar with conventional processing the sounding and reference signals are to be digitized at intermediate frequency band and to be processed digitally. The power spectrum bandwidth of noise signal which can be digitized with ADC depends on its sampling rate. The bandwidth of radar signal defines range resolution of any radar: the wider the spectrum the better the resolution. Actually this is the main bottleneck of high resolution Noise Radars: conventional processing doesn't enable to get both high range resolution and high dynamic range. In the paper we present a way to go around this drawback by changing signal processing ideology in noise radar. We present results of our consideration and design of high resolution Noise Radar which uses slow ADCs. The design is based upon generation of both probing and reference signals digitally and realization of their cross-correlation in an analog correlator. The output of the correlator is a narrowband signal that requires rather slow ADC to be sampled which nowadays may give up to 130 dB dynamic range.

  1. Performance of High-pressure-ratio Axial-flow Compressor Using Highly Cambered NACA 65-series Blower Blades at High Mach Numbers

    Science.gov (United States)

    Voit, Charles H; Guentert, Donald C; Dugan, James F

    1950-01-01

    A complete stage of an axial-flow compressor was designed and built to investigate the possibility of obtaining a high pressure ratio with an acceptable efficiency through the use of the optimum combination of high blade loading and high relative inlet Mach number. Over-all stage performance was investigated over a range of flows at equivalent tip speeds of 418 to 836 feet per second. At design speed (836 ft/sec), a peak total-pressure ration of 1.445 was obtained with an adiabatic efficiency of 0.89. For design angle of attack at the mean radius, a total-pressure ratio of 1.392 was obtained.

  2. High resolution 3-D wavelength diversity imaging

    Science.gov (United States)

    Farhat, N. H.

    1981-09-01

    A physical optics, vector formulation of microwave imaging of perfectly conducting objects by wavelength and polarization diversity is presented. The results provide the theoretical basis for optimal data acquisition and three-dimensional tomographic image retrieval procedures. These include: (a) the selection of highly thinned (sparse) receiving array arrangements capable of collecting large amounts of information about remote scattering objects in a cost effective manner and (b) techniques for 3-D tomographic image reconstruction and display in which polarization diversity data is fully accounted for. Data acquisition employing a highly attractive AMTDR (Amplitude Modulated Target Derived Reference) technique is discussed and demonstrated by computer simulation. Equipment configuration for the implementation of the AMTDR technique is also given together with a measurement configuration for the implementation of wavelength diversity imaging in a roof experiment aimed at imaging a passing aircraft. Extension of the theory presented to 3-D tomographic imaging of passive noise emitting objects by spectrally selective far field cross-correlation measurements is also given. Finally several refinements made in our anechoic-chamber measurement system are shown to yield drastic improvement in performance and retrieved image quality.

  3. High-resolution gravity model of Venus

    Science.gov (United States)

    Reasenberg, R. D.; Goldberg, Z. M.

    1992-01-01

    The anomalous gravity field of Venus shows high correlation with surface features revealed by radar. We extract gravity models from the Doppler tracking data from the Pioneer Venus Orbiter by means of a two-step process. In the first step, we solve the nonlinear spacecraft state estimation problem using a Kalman filter-smoother. The Kalman filter has been evaluated through simulations. This evaluation and some unusual features of the filter are discussed. In the second step, we perform a geophysical inversion using a linear Bayesian estimator. To allow an unbiased comparison between gravity and topography, we use a simulation technique to smooth and distort the radar topographic data so as to yield maps having the same characteristics as our gravity maps. The maps presented cover 2/3 of the surface of Venus and display the strong topography-gravity correlation previously reported. The topography-gravity scatter plots show two distinct trends.

  4. A Very High Spatial Resolution Detector for Small Animal PET

    Energy Technology Data Exchange (ETDEWEB)

    Kanai Shah, M.S.

    2007-03-06

    Positron Emission Tomography (PET) is an in vivo analog of autoradiography and has the potential to become a powerful new tool in imaging biological processes in small laboratory animals. PET imaging of small animals can provide unique information that can help in advancement of human disease models as well as drug development. Clinical PET scanners used for human imaging are bulky, expensive and do not have adequate spatial resolution for small animal studies. Hence, dedicated, low cost instruments are required for conducting small animal studies with higher spatial resolution than what is currently achieved with clinical as well as dedicated small animal PET scanners. The goal of the proposed project is to investigate a new all solid-state detector design for small animal PET imaging. Exceptionally high spatial resolution, good timing resolution, and excellent energy resolution are expected from the proposed detector design. The Phase I project was aimed at demonstrating the feasibility of producing high performance solid-state detectors that provide high sensitivity, spatial resolution, and timing characteristics. Energy resolution characteristics of the new detector were also investigated. The goal of the Phase II project is to advance the promising solid-state detector technology for small animal PET and determine its full potential. Detectors modules will be built and characterized and finally, a bench-top small animal PET system will be assembled and evaluated.

  5. High-resolution spectroscopy of gamma-ray transients

    Energy Technology Data Exchange (ETDEWEB)

    Cline, T.L.

    1988-09-25

    The first high-resolution spectrometer flown to observe gamma-ray bursts was launched on the ISEE-3 spacecraft over nine years ago. It recorded two events before instrument failure, giving results that were suggestive but marginal. Other studies, with coarser energy resolution, also show evidence for spectral features as well as for spectral evolution on short time scales. Absolute source strength calibration will be possible only with source identification, but understanding of the burst emission processes will surely come only from the measurements having the best spectral and temporal precision. The only high- resolution gamma-ray spectrometer now planned, here or abroad, for space flight is an instrument sequel to the ISEE-3 spectrometer, to be flown on the interplanetary 'GGS Wind' mission. Much larger and higher-sensitivity, high-resolution instruments may have their optimum opportunities in conjunction with studies of solar flares in the time frame of the solar maximum of 2002.

  6. Compact and high-resolution optical orbital angular momentum sorter

    Directory of Open Access Journals (Sweden)

    Chenhao Wan

    2017-03-01

    Full Text Available A compact and high-resolution optical orbital angular momentum (OAM sorter is proposed and demonstrated. The sorter comprises a quadratic fan-out mapper and a dual-phase corrector positioned in the pupil plane and the Fourier plane, respectively. The optical system is greatly simplified compared to previous demonstrations of OAM sorting, and the performance in resolution and efficiency is maintained. A folded configuration is set up using a single reflective spatial light modulator (SLM to demonstrate the validity of the scheme. The two phase elements are implemented on the left and right halves of the SLM and connected by a right-angle prism. Experimental results demonstrate the high resolution of the compact OAM sorter, and the current limit in efficiency can be overcome by replacing with transmissive SLMs and removing the beam splitters. This novel scheme paves the way for the miniaturization and integration of high-resolution OAM sorters.

  7. Climatologies at high resolution for the Earth land surface areas

    CERN Document Server

    Karger, Dirk Nikolaus; Böhner, Jürgen; Kawohl, Tobias; Kreft, Holger; Soria-Auza, Rodrigo Wilber; Zimmermann, Niklaus; Linder, H Peter; Kessler, Michael

    2016-01-01

    High resolution information of climatic conditions is essential to many application in environmental sciences. Here we present the CHELSA algorithm to downscale temperature and precipitation estimates from the European Centre for Medium-Range Weather Forecast (ECMWF) climatic reanalysis interim (ERA-Interim) to a high resolution of 30 arc sec. The algorithm for temperature is based on a statistical downscaling of atmospheric temperature from the ERA-Interim climatic reanalysis. The precipitation algorithm incorporates orographic predictors such as wind fields, valley exposition, and boundary layer height, and a bias correction using Global Precipitation Climatology Center (GPCC) gridded and Global Historical Climate Network (GHCN) station data. The resulting data consist of a monthly temperature and precipitation climatology for the years 1979-2013. We present a comparison of data derived from the CHELSA algorithm with two other high resolution gridded products with overlapping temporal resolution (Tropical R...

  8. High resolution single particle refinement in EMAN2.1.

    Science.gov (United States)

    Bell, James M; Chen, Muyuan; Baldwin, Philip R; Ludtke, Steven J

    2016-05-01

    EMAN2.1 is a complete image processing suite for quantitative analysis of grayscale images, with a primary focus on transmission electron microscopy, with complete workflows for performing high resolution single particle reconstruction, 2-D and 3-D heterogeneity analysis, random conical tilt reconstruction and subtomogram averaging, among other tasks. In this manuscript we provide the first detailed description of the high resolution single particle analysis pipeline and the philosophy behind its approach to the reconstruction problem. High resolution refinement is a fully automated process, and involves an advanced set of heuristics to select optimal algorithms for each specific refinement task. A gold standard FSC is produced automatically as part of refinement, providing a robust resolution estimate for the final map, and this is used to optimally filter the final CTF phase and amplitude corrected structure. Additional methods are in-place to reduce model bias during refinement, and to permit cross-validation using other computational methods.

  9. A rotational and axial motion system load frame insert for in situ high energy x-ray studies

    Energy Technology Data Exchange (ETDEWEB)

    Shade, Paul A., E-mail: paul.shade.1@us.af.mil; Schuren, Jay C.; Turner, Todd J. [Materials and Manufacturing Directorate, Air Force Research Laboratory, Wright-Patterson AFB, Ohio 45433 (United States); Blank, Basil [PulseRay, Beaver Dams, New York 14812 (United States); Kenesei, Peter; Goetze, Kurt; Lienert, Ulrich; Almer, Jonathan [Advanced Photon Source, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Suter, Robert M. [Carnegie Mellon University, Pittsburgh, Pennsylvania 15213 (United States); Bernier, Joel V.; Li, Shiu Fai [Engineering Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550 (United States); Lind, Jonathan [Carnegie Mellon University, Pittsburgh, Pennsylvania 15213 (United States); Engineering Directorate, Lawrence Livermore National Laboratory, Livermore, California 94550 (United States)

    2015-09-15

    High energy x-ray characterization methods hold great potential for gaining insight into the behavior of materials and providing comparison datasets for the validation and development of mesoscale modeling tools. A suite of techniques have been developed by the x-ray community for characterizing the 3D structure and micromechanical state of polycrystalline materials; however, combining these techniques with in situ mechanical testing under well characterized and controlled boundary conditions has been challenging due to experimental design requirements, which demand new high-precision hardware as well as access to high-energy x-ray beamlines. We describe the design and performance of a load frame insert with a rotational and axial motion system that has been developed to meet these requirements. An example dataset from a deforming titanium alloy demonstrates the new capability.

  10. High resolution temperature measurement technique for measuring marine heat flow

    Institute of Scientific and Technical Information of China (English)

    QIN; YangYang; YANG; XiaoQiu; WU; BaoZhen; SUN; ZhaoHua; SHI; XiaoBin

    2013-01-01

    High resolution temperature measurement technique is one of the key techniques for measuring marine heat flow. Basing on Pt1000 platinum resistance which has the characteristics of high accuracy and good stability, we designed a bridge reversal excitation circuit for high resolution temperature measurement. And the deep ocean floor in-situ test results show that: (1) temperature deviation and peak-to-peak resolution of the first version circuit board (V1) are 1.960-1.990 mK and 0.980-0.995 m Kat 1.2-2.7°C, respectively; and temperature deviation and peak-to-peak resolution of the second circuit board (V2) are 2.260mK and 1.130 mK at 1.2-1.3°C, respectively; (2) During the 2012NSFC-IndOcean cruise, seafloor geothermal gradient at Ind2012HF03,-07 and-12 stations (water depth ranges from 3841 to 4541 m) were successfully measured, the values are 59.1,75.1 and 71.6°C/km, respectively. And the measurement errors of geothermal gradient at these three stations are less than 3.0% in terms of the peak-to-peak resolution. These indicate that the high resolution temperature measurement technique based on Pt1000 platinum resistance in this paper can be applied to marine heat flow measurement to obtain high precision geothermal parameters.

  11. High resolution surface plasmon microscopy for cell imaging

    Science.gov (United States)

    Argoul, F.; Monier, K.; Roland, T.; Elezgaray, J.; Berguiga, L.

    2010-04-01

    We introduce a new non-labeling high resolution microscopy method for cellular imaging. This method called SSPM (Scanning Surface Plasmon Microscopy) pushes down the resolution limit of surface plasmon resonance imaging (SPRi) to sub-micronic scales. High resolution SPRi is obtained by the surface plasmon lauching with a high numerical aperture objective lens. The advantages of SPPM compared to other high resolution SPRi's rely on three aspects; (i) the interferometric detection of the back reflected light after plasmon excitation, (ii) the twodimensional scanning of the sample for image reconstruction, (iii) the radial polarization of light, enhancing both resolution and sensitivity. This microscope can afford a lateral resolution of - 150 nm in liquid environment and - 200 nm in air. We present in this paper images of IMR90 fibroblasts obtained with SSPM in dried environment. Internal compartments such as nucleus, nucleolus, mitochondria, cellular and nuclear membrane can be recognized without labelling. We propose an interpretation of the ability of SSPM to reveal high index contrast zones by a local decomposition of the V (Z) function describing the response of the SSPM.

  12. Liquid Scintillation High Resolution Spectral Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Grau Carles, A.; Grau Malonda, A.

    2010-08-06

    The CIEMAT/NIST and the TDCR methods in liquid scintillation counting are based on the determination of the efficiency for total counting. This paper tries to expand these methods analysing the pulse-height spectrum of radionuclides. To reach this objective we have to generalize the equations used in the model and to analyse the influence of ionization and chemical quench in both spectra and counting efficiency. We present equations to study the influence of different photomultipliers response in systems with one, two or three photomultipliers. We study the effect of the electronic noise discriminator level in both spectra and counting efficiency. The described method permits one to study problems that up to now was not possible to approach, such as the high uncertainty in the standardization of pure beta-ray emitter with low energy when we apply the TDCR method, or the discrepancies in the standardization of some electron capture radionuclides, when the CIEMAT/NIST method is applied. (Author) 107 refs.

  13. Axial Ligand Effects on the Structures of Self-Assembled Gallium-Porphyrin Monolayers on Highly Oriented Pyrolytic Graphite.

    Science.gov (United States)

    Kamm, Judith M; Iverson, Cameron P; Lau, Wing-Yeung; Hopkins, Michael D

    2016-01-19

    Monolayers of five-coordinate gallium octaethylporphyrin complexes (Ga(OEP)X; X = Cl, Br, I, O3SCF3, CCPh) on highly oriented pyrolytic graphite were studied at the solid-liquid (1-phenyloctane) interface using scanning tunneling microscopy (STM) to probe the dependence of their properties on the nature of the axial X ligand. Density functional theory calculations of the gas-phase structures of the free molecules reveal that the gallium atom is positioned above the plane of the porphyrin macrocycle, with this pyramidal distortion increasing in magnitude according to X = O3SCF3 (displacement = 0.35 Å) monolayers are sensitive to the nature of the axial ligand: the monolayers of Ga(OEP)(O3SCF3) and Ga(OEP)(CCPh) exhibit damage during the STM experiment upon repeated scanning and upon toggling the sign of the bias potential, but monolayers of Ga(OEP)Cl, Ga(OEP)Br, and Ga(OEP)I do not. A second important ligand-influenced property is that Ga(OEP)I forms bilayer structures, whereas the other Ga(OEP)X compounds form monolayers exclusively under identical conditions. The top layer of the Ga(OEP)I bilayer is oriented with the iodo ligand directed away from the surface, like the bottom layer, but the molecules pack in a square, lower-density geometry. The comparatively large polarizability of the iodo ligand is suggested to be important in stabilizing the bilayer structure.

  14. High-resolution spectroscopy of gases for industrial applications

    DEFF Research Database (Denmark)

    Fateev, Alexander; Clausen, Sønnik

    High-resolution spectroscopy of gases is a powerful technique which has various fundamental and practical applications: in situ simultaneous measurements of gas temperature and gas composition, radiative transfer modeling, validation of existing and developing of new databases and etc. Existing...... for analysis of complex experimental data and further development of the databases. High-temperature gas cell facilities available at DTU Chemical Engineering are presented and described. The gas cells and high-resolution spectrometers allow us to perform high-quality reference measurements of gases relevant...

  15. High resolution positron tomography using PCR-I

    Energy Technology Data Exchange (ETDEWEB)

    Brownell, G.L.; Burnham, C.A.; Sandrew, B.; Elmaleh, D.R.; Livni, E.; Kizuka, H.

    1984-01-01

    PCR-I is a high resolution positron tomograph developed by the Physics Research Laboratory of the Massachusetts General Hospital to explore resolution limits of positron tomographs. PCR-I currently obtains images with 4.8 mm FWHM resolution at the center. Plane thickness may be varied between 5 and 10 mm. The instrument uses analog coding to obtain high resolution images without mechanical motion. This permits rapid dynamic imaging and gated cardiac imaging as well as conventional high resolution imaging. A series of studies has been carried out to demonstrate the ability of PCR-I to image structures in small animals. F-18 in the rat skeleton is clearly defined and various structures such as the spinal processes can be clearly resolved. A sequence of images at different spacing provides a three-dimensional reconstruction of the rat skeleton. Blood volume and palmitic acid have been imaged in the dog heart. Again, the sequence of images provides a clear delineation of the three dimensional nature of the blood pools and of the surrounding musculature. Blood flow, blood volume and glucose metabolism have been studied in the monkey brain. Structures within the brain of the Resus monkey can be clearly resolved. Increased activity resulting from induced seizures in the squirrel monkey have been observed and delineated. All of these studies indicate areas of future animal and clinical research using the high resolution tomograph, PCR-I.

  16. High-resolution neutron microtomography with noiseless neutron counting detector

    Energy Technology Data Exchange (ETDEWEB)

    Tremsin, A.S., E-mail: ast@ssl.berkeley.edu [Space Sciences Laboratory, University of California, Berkeley, CA 94720 (United States); McPhate, J.B.; Vallerga, J.V.; Siegmund, O.H.W. [Space Sciences Laboratory, University of California, Berkeley, CA 94720 (United States); Feller, W.B. [Nova Scientific Inc., 10 Picker Road, Sturbridge, MA 01566 (United States); Lehmann, E. [Paul Scherrer Institute, CH-5232 Villigen (Switzerland); Butler, L.G. [Louisiana State University, Baton Rouge, LA 70803 (United States); Dawson, M. [Helmholtz Centre Berlin for Materials and Energy (Germany)

    2011-10-01

    The improved collimation and intensity of thermal and cold neutron beamlines combined with recent advances in neutron imaging devices enable high-resolution neutron radiography and microtomography, which can provide information on the internal structure of objects not achievable with conventional X-ray imaging techniques. Neutron detection efficiency, spatial and temporal resolution (important for the studies of dynamic processes) and low background count rate are among the crucial parameters defining the quality of radiographic images and tomographic reconstructions. The unique capabilities of neutron counting detectors with neutron-sensitive microchannel plates (MCPs) and with Timepix CMOS readouts providing high neutron detection efficiency ({approx}70% for cold neutrons), spatial resolutions ranging from 15 to 55 {mu}m and a temporal resolution of {approx}1 {mu}s-combined with the virtual absence of readout noise-make these devices very attractive for high-resolution microtomography. In this paper we demonstrate the capabilities of an MCP-Timepix detection system applied to microtomographic imaging, performed at the ICON cold neutron facility of the Paul Scherrer Institute. The high resolution and the absence of readout noise enable accurate reconstruction of texture in a relatively opaque wood sample, differentiation of internal tissues of a fly and imaging of individual {approx}400 {mu}m grains in an organic powder encapsulated in a {approx}700 {mu}m thick metal casing.

  17. Extension of least squares spectral resolution algorithm to high-resolution lipidomics data

    Energy Technology Data Exchange (ETDEWEB)

    Zeng, Ying-Xu [Department of Chemistry, University of Bergen, PO Box 7803, N-5020 Bergen (Norway); Mjøs, Svein Are, E-mail: svein.mjos@kj.uib.no [Department of Chemistry, University of Bergen, PO Box 7803, N-5020 Bergen (Norway); David, Fabrice P.A. [Bioinformatics and Biostatistics Core Facility, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL) and Swiss Institute of Bioinformatics (SIB), Lausanne (Switzerland); Schmid, Adrien W. [Proteomics Core Facility, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne (Switzerland)

    2016-03-31

    Lipidomics, which focuses on the global study of molecular lipids in biological systems, has been driven tremendously by technical advances in mass spectrometry (MS) instrumentation, particularly high-resolution MS. This requires powerful computational tools that handle the high-throughput lipidomics data analysis. To address this issue, a novel computational tool has been developed for the analysis of high-resolution MS data, including the data pretreatment, visualization, automated identification, deconvolution and quantification of lipid species. The algorithm features the customized generation of a lipid compound library and mass spectral library, which covers the major lipid classes such as glycerolipids, glycerophospholipids and sphingolipids. Next, the algorithm performs least squares resolution of spectra and chromatograms based on the theoretical isotope distribution of molecular ions, which enables automated identification and quantification of molecular lipid species. Currently, this methodology supports analysis of both high and low resolution MS as well as liquid chromatography-MS (LC-MS) lipidomics data. The flexibility of the methodology allows it to be expanded to support more lipid classes and more data interpretation functions, making it a promising tool in lipidomic data analysis. - Highlights: • A flexible strategy for analyzing MS and LC-MS data of lipid molecules is proposed. • Isotope distribution spectra of theoretically possible compounds were generated. • High resolution MS and LC-MS data were resolved by least squares spectral resolution. • The method proposed compounds that are likely to occur in the analyzed samples. • The proposed compounds matched results from manual interpretation of fragment spectra.

  18. High Resolution Depth-Resolved Imaging From Multi-Focal Images for Medical Ultrasound

    DEFF Research Database (Denmark)

    Diamantis, Konstantinos; Dalgarno, Paul A.; Greenaway, Alan H.

    2015-01-01

    An ultrasound imaging technique providing subdiffraction limit axial resolution for point sources is proposed. It is based on simultaneously acquired multi-focal images of the same object, and on the image metric of sharpness. The sharpness is extracted by image data and presents higher values...... for in-focus images. The technique is derived from biological microscopy and is validated here with simulated ultrasound data. A linear array probe is used to scan a point scatterer phantom that moves in depth with a controlled step. From the beamformed responses of each scatterer position the image...... calibration curves combined with the use of a maximum-likelihood algorithm is then able to estimate, with high precision, the depth location of any emitter fron each single image. Estimated values are compared with the ground truth demonstrating that an accuracy of 28.6 µm (0.13λ) is achieved for a 4 mm depth...

  19. High-resolution CT: pre-operative assessment of chronic and recurrent rhinosinusitis

    Energy Technology Data Exchange (ETDEWEB)

    Ferrie, J.C. [Dept. of Radiology A, University Hospital, 86 Poitiers (France); Vandermarcq, P. [Dept. of Radiology A, University Hospital, 86 Poitiers (France); Azais, O. [Dept. of Radiology A, University Hospital, 86 Poitiers (France); Klossek, J.M. [Dept. of Oto-Rhino-Laryngology, University Hospital, 86 Poitiers (France); Drouineau, J. [Dept. of Radiology A, University Hospital, 86 Poitiers (France)

    1993-04-01

    The better understanding of chronic and recurrent rhinosinusitis and the advance in endoscopic endonasal surgery have modified the radiological pre-operative investigation of this condition. The ethmoid labyrinth, not accessible to the endoscope, may be explored by axial and coronal high-resolution thin section (2 mm) CT. We have reviewed 100 CT scans with endoscopic correlation in order to assess the accuracy of this pre-operative method. This anatomical study reveals the presence and extent of parasinus diseases which are usually concentrated in the area of the ostiomeatal unit. The anatomic variations of the lateral nasal wall that have been reporded as predisposing to sinusitis and the morphologic variations altering the relationships of the ethmoid with the orbits and the brain were also studied. This pre-operative radiological assessment is currently necessary for functional and safe surgery. (orig.)

  20. Ultra-high resolution polarization-sensitive optical coherence microscopy for brain imaging at 6 um, 3.4 um and 1.3 um resolution (Conference Presentation)

    Science.gov (United States)

    Wang, Hui; Akkin, Taner; Magnain, Caroline V.; Yaseen, Mohammad A.; Cramer, Avilash; Wang, Ruopeng; Sakadžic, Sava; Boas, David A.

    2016-03-01

    Neuroanatomical pathways form the basis for functional activity of brain circuits. In the past, we developed a polarization-sensitive optical coherence tomography with serial scanning to achieve large-scale brain imaging. The system was able to visualize 3D fiber tracts of ~20 um in diameter. To investigate the neuroanatomical pathways at finer scales, we have now built a polarization-maintaining fiber based ultra-high resolution polarization-sensitive optical coherence microscope (PS-OCM) at 1300 nm. The PS-OCM has an axial resolution of 3.5 um in tissue. The detection setup consists of two spectrometers, acquiring spectral interference on orthogonal polarization channels. With a single measurement, the setup generates four contrasts: reflectivity, cross-polarization, retardance and optic axis orientation. To investigate the capability of PS-OCM at different resolutions, we used three microscope objectives that yield lateral resolutions of 6.0 um, 3.4 um and 1.3 um. Blocks of formalin fixed mouse brain and human brain were scanned. The cross-polarization and retardance images clearly depict the neuronal fiber structures, which are comparable with that generated by the maximum projection of volumetric reflectivity data. The optic axis orientation quantifies the in-plane fiber orientation. With the lateral resolution of 1.3 um, the retardance contrast is weak in white matter due to the shallow depth of focus. Overall, the ultra-high resolution PS-OCM provides a new tool to reveal neuroanatomical maps in the brain at cellular resolution.

  1. Accelerated High-Resolution Photoacoustic Tomography via Compressed Sensing

    CERN Document Server

    Arridge, Simon; Betcke, Marta; Cox, Ben; Huynh, Nam; Lucka, Felix; Ogunlade, Olumide; Zhang, Edward

    2016-01-01

    Current 3D photoacoustic tomography (PAT) systems offer either high image quality or high frame rates but are not able to deliver high spatial and temporal resolution simultaneously, which limits their ability to image dynamic processes in living tissue. A particular example is the planar Fabry-Perot (FP) scanner, which yields high-resolution images but takes several minutes to sequentially map the photoacoustic field on the sensor plane, point-by-point. However, as the spatio-temporal complexity of many absorbing tissue structures is rather low, the data recorded in such a conventional, regularly sampled fashion is often highly redundant. We demonstrate that combining variational image reconstruction methods using spatial sparsity constraints with the development of novel PAT acquisition systems capable of sub-sampling the acoustic wave field can dramatically increase the acquisition speed while maintaining a good spatial resolution: First, we describe and model two general spatial sub-sampling schemes. Then...

  2. High Resolution Muon Computed Tomography at Neutrino Beam Facilities

    CERN Document Server

    Suerfu, Burkhant

    2015-01-01

    X-ray computed tomography (CT) has an indispensable role in constructing 3D images of objects made from light materials. However, limited by absorption coefficients, X-rays cannot deeply penetrate materials such as copper and lead. Here we show via simulation that muon beams can provide high resolution tomographic images of dense objects and of structures within the interior of dense objects. The effects of resolution broadening from multiple scattering diminish with increasing muon momentum. As the momentum of the muon increases, the contrast of the image goes down and therefore requires higher resolution in the muon spectrometer to resolve the image. The variance of the measured muon momentum reaches a minimum and then increases with increasing muon momentum. The impact of the increase in variance is to require a higher integrated muon flux to reduce fluctuations. The flux requirements and level of contrast needed for high resolution muon computed tomography are well matched to the muons produced in the pio...

  3. Performance of a high resolution cavity beam position monitor system

    Science.gov (United States)

    Walston, Sean; Boogert, Stewart; Chung, Carl; Fitsos, Pete; Frisch, Joe; Gronberg, Jeff; Hayano, Hitoshi; Honda, Yosuke; Kolomensky, Yury; Lyapin, Alexey; Malton, Stephen; May, Justin; McCormick, Douglas; Meller, Robert; Miller, David; Orimoto, Toyoko; Ross, Marc; Slater, Mark; Smith, Steve; Smith, Tonee; Terunuma, Nobuhiro; Thomson, Mark; Urakawa, Junji; Vogel, Vladimir; Ward, David; White, Glen

    2007-07-01

    It has been estimated that an RF cavity Beam Position Monitor (BPM) could provide a position measurement resolution of less than 1 nm. We have developed a high resolution cavity BPM and associated electronics. A triplet comprised of these BPMs was installed in the extraction line of the Accelerator Test Facility (ATF) at the High Energy Accelerator Research Organization (KEK) for testing with its ultra-low emittance beam. The three BPMs were each rigidly mounted inside an alignment frame on six variable-length struts which could be used to move the BPMs in position and angle. We have developed novel methods for extracting the position and tilt information from the BPM signals including a robust calibration algorithm which is immune to beam jitter. To date, we have demonstrated a position resolution of 15.6 nm and a tilt resolution of 2.1 μrad over a dynamic range of approximately ±20 μm.

  4. Resolution-recovery-embedded image reconstruction for a high-resolution animal SPECT system.

    Science.gov (United States)

    Zeraatkar, Navid; Sajedi, Salar; Farahani, Mohammad Hossein; Arabi, Hossein; Sarkar, Saeed; Ghafarian, Pardis; Rahmim, Arman; Ay, Mohammad Reza

    2014-11-01

    The small-animal High-Resolution SPECT (HiReSPECT) is a dedicated dual-head gamma camera recently designed and developed in our laboratory for imaging of murine models. Each detector is composed of an array of 1.2 × 1.2 mm(2) (pitch) pixelated CsI(Na) crystals. Two position-sensitive photomultiplier tubes (H8500) are coupled to each head's crystal. In this paper, we report on a resolution-recovery-embedded image reconstruction code applicable to the system and present the experimental results achieved using different phantoms and mouse scans. Collimator-detector response functions (CDRFs) were measured via a pixel-driven method using capillary sources at finite distances from the head within the field of view (FOV). CDRFs were then fitted by independent Gaussian functions. Thereafter, linear interpolations were applied to the standard deviation (σ) values of the fitted Gaussians, yielding a continuous map of CDRF at varying distances from the head. A rotation-based maximum-likelihood expectation maximization (MLEM) method was used for reconstruction. A fast rotation algorithm was developed to rotate the image matrix according to the desired angle by means of pre-generated rotation maps. The experiments demonstrated improved resolution utilizing our resolution-recovery-embedded image reconstruction. While the full-width at half-maximum (FWHM) radial and tangential resolution measurements of the system were over 2 mm in nearly all positions within the FOV without resolution recovery, reaching around 2.5 mm in some locations, they fell below 1.8 mm everywhere within the FOV using the resolution-recovery algorithm. The noise performance of the system was also acceptable; the standard deviation of the average counts per voxel in the reconstructed images was 6.6% and 8.3% without and with resolution recovery, respectively.

  5. Isotope specific resolution recovery image reconstruction in high resolution PET imaging.

    Science.gov (United States)

    Kotasidis, Fotis A; Angelis, Georgios I; Anton-Rodriguez, Jose; Matthews, Julian C; Reader, Andrew J; Zaidi, Habib

    2014-05-01

    Measuring and incorporating a scanner-specific point spread function (PSF) within image reconstruction has been shown to improve spatial resolution in PET. However, due to the short half-life of clinically used isotopes, other long-lived isotopes not used in clinical practice are used to perform the PSF measurements. As such, non-optimal PSF models that do not correspond to those needed for the data to be reconstructed are used within resolution modeling (RM) image reconstruction, usually underestimating the true PSF owing to the difference in positron range. In high resolution brain and preclinical imaging, this effect is of particular importance since the PSFs become more positron range limited and isotope-specific PSFs can help maximize the performance benefit from using resolution recovery image reconstruction algorithms. In this work, the authors used a printing technique to simultaneously measure multiple point sources on the High Resolution Research Tomograph (HRRT), and the authors demonstrated the feasibility of deriving isotope-dependent system matrices from fluorine-18 and carbon-11 point sources. Furthermore, the authors evaluated the impact of incorporating them within RM image reconstruction, using carbon-11 phantom and clinical datasets on the HRRT. The results obtained using these two isotopes illustrate that even small differences in positron range can result in different PSF maps, leading to further improvements in contrast recovery when used in image reconstruction. The difference is more pronounced in the centre of the field-of-view where the full width at half maximum (FWHM) from the positron range has a larger contribution to the overall FWHM compared to the edge where the parallax error dominates the overall FWHM. Based on the proposed methodology, measured isotope-specific and spatially variant PSFs can be reliably derived and used for improved spatial resolution and variance performance in resolution recovery image reconstruction. The

  6. SIM and PALM: high-resolution microscopy methods and their consequences for cell biology

    Science.gov (United States)

    Krampert, Gerhard; Kleppe, Ingo; Kalkbrenner, Thomas; Weisshart, Klaus; Wolleschensky, Ralf; Kempe, Michael

    2010-04-01

    The diffraction limit in traditional fluorescence microscopy (approximately 200 and 600 nanometers in lateral and axial directions, respectively) has restricted the applications in bio-medical research. However, over the last 10 years various techniques have emerged to overcome this limit. Each of these techniques has its own characteristics that influence its application in biology. This paper will show how two of the techniques, Structured Illumination Microscopy (SIM) and PhotoActivated Localization Microscopy (PALM), complement each other in imaging of biological samples beyond the resolution of classical widefield fluorescence microscopy. As a reference the properties of two well known standard imaging techniques in this field, confocal Laser Scanning Microscopy (LSM) and Total Internal Reflection (TIRF) microscopy, are compared to the properties of the two high resolution techniques. Combined SIM/PALM imaging allows the extremely accurate localization of individual molecules within the context of various fluorescent structures already resolved in 3D with a resolution of up to 100nm using SIM. Such a combined system provides the biologist with an unprecedented view of the sub-cellular organization of life.

  7. High-resolution handheld rigid endomicroscope based on full-field optical coherence tomography

    Science.gov (United States)

    Benoit a la Guillaume, Emilie; Martins, Franck; Boccara, Claude; Harms, Fabrice

    2016-02-01

    Full-field optical coherence tomography (FF-OCT) is a powerful tool for nondestructive assessment of biological tissue, i.e., for the structural examination of tissue in depth at a cellular resolution. Mostly known as a microscopy device for ex vivo analysis, FF-OCT has also been adapted to endoscopy setups since it shows good potential for in situ cancer diagnosis and biopsy guidance. Nevertheless, all the attempts to perform endoscopic FF-OCT imaging did not go beyond lab setups. We describe here, to the best of our knowledge, the first handheld FF-OCT endoscope based on a tandem interferometry assembly using incoherent illumination. A common-path passive imaging interferometer at the tip of an optical probe makes it robust and insensitive to environmental perturbations, and a low finesse Fabry-Perot processing interferometer guarantees a compact system. A good resolution (2.7 μm transverse and 6 μm axial) is maintained through the long distance, small diameter relay optics of the probe, and a good signal-to-noise ratio is achieved in a limited 100 ms acquisition time. High-resolution images and a movie of a rat brain slice have been recorded by moving the contact endoscope over the surface of the sample, allowing for tissue microscopic exploration at 20 μm under the surface. These promising ex vivo results open new perspectives for in vivo imaging of biological tissue, in particular, in the field of cancer and surgical margin assessment.

  8. Extension of least squares spectral resolution algorithm to high-resolution lipidomics data.

    Science.gov (United States)

    Zeng, Ying-Xu; Mjøs, Svein Are; David, Fabrice P A; Schmid, Adrien W

    2016-03-31

    Lipidomics, which focuses on the global study of molecular lipids in biological systems, has been driven tremendously by technical advances in mass spectrometry (MS) instrumentation, particularly high-resolution MS. This requires powerful computational tools that handle the high-throughput lipidomics data analysis. To address this issue, a novel computational tool has been developed for the analysis of high-resolution MS data, including the data pretreatment, visualization, automated identification, deconvolution and quantification of lipid species. The algorithm features the customized generation of a lipid compound library and mass spectral library, which covers the major lipid classes such as glycerolipids, glycerophospholipids and sphingolipids. Next, the algorithm performs least squares resolution of spectra and chromatograms based on the theoretical isotope distribution of molecular ions, which enables automated identification and quantification of molecular lipid species. Currently, this methodology supports analysis of both high and low resolution MS as well as liquid chromatography-MS (LC-MS) lipidomics data. The flexibility of the methodology allows it to be expanded to support more lipid classes and more data interpretation functions, making it a promising tool in lipidomic data analysis.

  9. Study of Saturn electrostatic discharges with high time resolution

    Science.gov (United States)

    Zakharenko, V.; Mylostna, K.; Konovalenko, A.; Kolyadin, V.; Zarka, P.; Griessmeier, J.-M.; Litvinenko, G.; Sidorchuk, M.; Rucker, H.; Fischer, G.; Cecconi, B.; Coffre, A.; Denis, L.; Shevchenko, V.; Nikolaenko, V.

    2013-09-01

    Ground-based observations of SED (Saturn Electrostatic Discharges) with high time resolution are the next stage of extraterrestrial atmospheric processes study. Due to extremely high intensity of Saturn's storm J (2010) [1] we have obtained the records with high signal-to-noise (S/N) ratio with the time resolution of 15 ns. It permitted us to investigate the microsecond structure of lightning and clearly distinguish SED in the presence of local interference in virtue of a dispersive delay of extraterrestrial planetary signals.

  10. Evacuee Compliance Behavior Analysis using High Resolution Demographic Information

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Wei [ORNL; Han, Lee [University of Tennessee, Knoxville (UTK); Liu, Cheng [ORNL; Tuttle, Mark A [ORNL; Bhaduri, Budhendra L [ORNL

    2014-01-01

    The purpose of this study is to examine whether evacuee compliance behavior with route assignments from different resolutions of demographic data would impact the evacuation performance. Most existing evacuation strategies assume that travelers will follow evacuation instructions, while in reality a certain percent of evacuees do not comply with prescribed instructions. In this paper, a comparison study of evacuation assignment based on Traffic Analysis Zones (TAZ) and high resolution LandScan USA Population Cells (LPC) were conducted for the detailed road network representing Alexandria, Virginia. A revised platform for evacuation modeling built on high resolution demographic data and activity-based microscopic traffic simulation is proposed. The results indicate that evacuee compliance behavior affects evacuation efficiency with traditional TAZ assignment, but it does not significantly compromise the efficiency with high resolution LPC assignment. The TAZ assignment also underestimates the real travel time during evacuation, especially for high compliance simulations. This suggests that conventional evacuation studies based on TAZ assignment might not be effective at providing efficient guidance to evacuees. From the high resolution data perspective, traveler compliance behavior is an important factor but it does not impact the system performance significantly. The highlight of evacuee compliance behavior analysis should be emphasized on individual evacuee level route/shelter assignments, rather than the whole system performance.

  11. Design and implementation of spaceborne high resolution infrared touch screen

    Science.gov (United States)

    Li, Tai-guo; Li, Wen-xin; Dong, Yi-peng; Ma, Wen; Xia, Jia-gao

    2015-10-01

    For the consideration of the special application environment of the electronic products used in aerospace and to further more improve the human-computer interaction of the manned aerospace area. The research is based on the design and implementation way of the high resolution spaceborne infrared touch screen on the basis of FPGA and DSP frame structure. Beside the introduction of the whole structure for the high resolution spaceborne infrared touch screen system, this essay also gives the detail information about design of hardware for the high resolution spaceborne infrared touch screen system, FPGA design, GUI design and DSP algorithm design based on Lagrange interpolation. What is more, the easy makes a comprehensive research of the reliability design for the high resolution spaceborne infrared touch screen for the special purpose of it. Besides, the system test is done after installation of spaceborne infrared touch screen. The test result shows that the system is simple and reliable enough, which has a stable running environment and high resolution, which certainly can meet the special requirement of the manned aerospace instrument products.

  12. Axial scanning in confocal microscopy employing adaptive lenses (CAL).

    Science.gov (United States)

    Koukourakis, Nektarios; Finkeldey, Markus; Stürmer, Moritz; Leithold, Christoph; Gerhardt, Nils C; Hofmann, Martin R; Wallrabe, Ulrike; Czarske, Jürgen W; Fischer, Andreas

    2014-03-10

    In this paper we analyze the capability of adaptive lenses to replace mechanical axial scanning in confocal microscopy. The adaptive approach promises to achieve high scan rates in a rather simple implementation. This may open up new applications in biomedical imaging or surface analysis in micro- and nanoelectronics, where currently the axial scan rates and the flexibility at the scan process are the limiting factors. The results show that fast and adaptive axial scanning is possible using electrically tunable lenses but the performance degrades during the scan. This is due to defocus and spherical aberrations introduced to the system by tuning of the adaptive lens. These detune the observation plane away from the best focus which strongly deteriorates the axial resolution by a factor of ~2.4. Introducing balancing aberrations allows addressing these influences. The presented approach is based on the employment of a second adaptive lens, located in the detection path. It enables shifting the observation plane back to the best focus position and thus creating axial scans with homogeneous axial resolution. We present simulated and experimental proof-of-principle results.

  13. Developing Visual Editors for High-Resolution Haptic Patterns

    DEFF Research Database (Denmark)

    Cuartielles, David; Göransson, Andreas; Olsson, Tony;

    2012-01-01

    In this article we give an overview of our iterative work in developing visual editors for creating high resolution haptic patterns to be used in wearable, haptic feedback devices. During the past four years we have found the need to address the question of how to represent, construct and edit high...

  14. Stars and planets at high spatial and spectral resolution

    NARCIS (Netherlands)

    Albrecht, Simon

    2008-01-01

    The work presented in this thesis involves the development of new instrumental techniques and analysing tools, combining high spectral resolution with high spatial information, with the aim to increase our understanding of the formation and evolution of stars and planets. First, a novel instrumental

  15. Achieving High Resolution Timer Events in Virtualized Environment.

    Directory of Open Access Journals (Sweden)

    Blazej Adamczyk

    Full Text Available Virtual Machine Monitors (VMM have become popular in different application areas. Some applications may require to generate the timer events with high resolution and precision. This however may be challenging due to the complexity of VMMs. In this paper we focus on the timer functionality provided by five different VMMs-Xen, KVM, Qemu, VirtualBox and VMWare. Firstly, we evaluate resolutions and precisions of their timer events. Apparently, provided resolutions and precisions are far too low for some applications (e.g. networking applications with the quality of service. Then, using Xen virtualization we demonstrate the improved timer design that greatly enhances both the resolution and precision of achieved timer events.

  16. High-resolution structure of viruses from random diffraction snapshots

    CERN Document Server

    Hosseinizadeh, A; Dashti, A; Fung, R; D'Souza, R M; Ourmazd, A

    2014-01-01

    The advent of the X-ray Free Electron Laser (XFEL) has made it possible to record diffraction snapshots of biological entities injected into the X-ray beam before the onset of radiation damage. Algorithmic means must then be used to determine the snapshot orientations and thence the three-dimensional structure of the object. Existing Bayesian approaches are limited in reconstruction resolution typically to 1/10 of the object diameter, with the computational expense increasing as the eighth power of the ratio of diameter to resolution. We present an approach capable of exploiting object symmetries to recover three-dimensional structure to high resolution, and thus reconstruct the structure of the satellite tobacco necrosis virus to atomic level. Our approach offers the highest reconstruction resolution for XFEL snapshots to date, and provides a potentially powerful alternative route for analysis of data from crystalline and nanocrystalline objects.

  17. New high resolution synthetic stellar libraries for the Gaia Mission

    CERN Document Server

    Sordo, R; Bouret, J C; Brott, I; Edvardsson, B; Frémat, Y; Heber, U; Josselin, E; Kochukhov, O; Korn, A; Lanzafame, A; Martins, F; Schweitzer, A; Thévenin, F; Zorec, J

    2008-01-01

    High resolution synthetic stellar libraries are of fundamental importance for the preparation of the Gaia Mission. We present new sets of spectral stellar libraries covering two spectral ranges: 300 --1100 nm at 0.1 nm resolution, and 840 -- 890 nm at 0.001 nm resolution. These libraries span a large range in atmospheric parameters, from super-metal-rich to very metal-poor (-5.0 $<$[Fe/H]$<$+1.0), from cool to hot (\\teff=3000--50000 K) stars, including peculiar abundance variations. The spectral resolution, spectral type coverage and number of models represent a substantial improvement over previous libraries used in population synthesis models and in atmospheric analysis.

  18. Kinetic modeling of a high power fast-axial-flow CO2 laser with computational fluid dynamics method

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    A new computational fluid dynamics (CFD) method for the simulation of fast-axial-flow CO2 laser is developed.The model which is solved by CFD software uses a set of dynamic differential equations to describe the dynamic process in one discharge tube.The velocity,temperature,pressure and turbulence energy distributions in discharge passage are presented.There is a good agreement between the theoretical prediction and the experimental results.This result indicates that the parameters of the laser have significant effect on the flow distribution in the discharge passage.It is helpful to optimize the output of high power CO2 laser by mastering its kinetic characteristics.

  19. Characteristic and magnetic field analysis of a high temperature superconductor axial-flux coreless induction maglev motor

    Science.gov (United States)

    Wei, Qin; Yu, Fan; Jin, Fang; Shuo, Li; Guoguo, Li; Gang, Lv

    2012-04-01

    A new high temperature superconductor axial-flux coreless maglev motor (HTS AFIM) is proposed, of which the primary windings are made of HTS tapes and the secondary is a non-magnetic conductor. The main works of this paper are the magnetic-field computation and characteristics analysis of HTS AFIM. For the first one, the reduction of magnetic fields near outer and inner radius of the HTS AFIM is solved by introducing the sub-loop electro-magnetic model along the radial position. For the second one, the AC losses of HTS coils are calculated. The relationships between the device's characteristics and device parameters are presented, and the results indicate that under certain frequency and current levitation device can output enough lift force. The conclusions are verified by finite element calculations.

  20. Characteristic and magnetic field analysis of a high temperature superconductor axial-flux coreless induction maglev motor.

    Science.gov (United States)

    Wei, Qin; Yu, Fan; Jin, Fang; Shuo, Li; Guoguo, Li; Gang, Lv

    2012-04-01

    A new high temperature superconductor axial-flux coreless maglev motor (HTS AFIM) is proposed, of which the primary windings are made of HTS tapes and the secondary is a non-magnetic conductor. The main works of this paper are the magnetic-field computation and characteristics analysis of HTS AFIM. For the first one, the reduction of magnetic fields near outer and inner radius of the HTS AFIM is solved by introducing the sub-loop electro-magnetic model along the radial position. For the second one, the AC losses of HTS coils are calculated. The relationships between the device's characteristics and device parameters are presented, and the results indicate that under certain frequency and current levitation device can output enough lift force. The conclusions are verified by finite element calculations.

  1. Subcutaneous Cysticercosis: Role of High Resolution Ultrasound in Diagnosis

    Directory of Open Access Journals (Sweden)

    Sachin Lohra

    2014-02-01

    Full Text Available BACKGROUND: Though the commonest site of extraintestinal infestation with Taenia solium is brain, Subcutaneous cysticercosis is fairly common in asia. The advent of high resolution ultrasound, FNAC, and a heightened clinician awareness of the existence of isolated soft tissue cysticerci has probably supplanted the need for surgical intervention and excision biopsy in asymptomatic subcutaneous cysts, as cysts have high rate of spontaneous resolution. OBJECTIVES: - To observe role of high resolution ultrasound in diagnosis and need of surgical intervention in treatment of subcutaneous cysticercosis. MATERIALS and METHODS: retrospective study of seven cases of extraneural cysticercosis, all involving the subcutaneous tissues or muscles over the arms and torso. Either high resolution ultrasound, FNAC, or excision biopsy, or a combination of these were used to arrive at a diagnosis. All patients were followed up with serial ultrasounds. All patients received oral nitazoxanide for autoinfection. Surgical excision was resorted to in two patients, in whom it was possible to obtain a histopathologic diagnosis. RESULTS: of the seven cases of subcutaneous cysticercosis all have rural background, most of the patients (6 were vegetarian and one was non vegetarian. Age and gender of patient, size and duration of lesion were insignificant in establishing the diagnosis. High resolution ultrasound was highly significant in establishing the diagnosis over FNAC and histopathology. Five of the cases resolved spontaneously and surgical intervention was required only in two cases. INTERPRETATION and CONCLUSIONS: With heightened clinician awareness of the existence of isolated subcutaneous cysticercosis in patients with close animal contact, and the widespread availability of high resolution ultrasound and FNAC, subcutaneous cysticercosis can be diagnosed readily. Surgery can be avoided in the great majority of these patients, as the cysts mostly resolve on their own

  2. High-resolution DEM Effects on Geophysical Flow Models

    Science.gov (United States)

    Williams, M. R.; Bursik, M. I.; Stefanescu, R. E. R.; Patra, A. K.

    2014-12-01

    Geophysical mass flow models are numerical models that approximate pyroclastic flow events and can be used to assess the volcanic hazards certain areas may face. One such model, TITAN2D, approximates granular-flow physics based on a depth-averaged analytical model using inputs of basal and internal friction, material volume at a coordinate point, and a GIS in the form of a digital elevation model (DEM). The volume of modeled material propagates over the DEM in a way that is governed by the slope and curvature of the DEM surface and the basal and internal friction angles. Results from TITAN2D are highly dependent upon the inputs to the model. Here we focus on a single input: the DEM, which can vary in resolution. High resolution DEMs are advantageous in that they contain more surface details than lower-resolution models, presumably allowing modeled flows to propagate in a way more true to the real surface. However, very high resolution DEMs can create undesirable artifacts in the slope and curvature that corrupt flow calculations. With high-resolution DEMs becoming more widely available and preferable for use, determining the point at which high resolution data is less advantageous compared to lower resolution data becomes important. We find that in cases of high resolution, integer-valued DEMs, very high-resolution is detrimental to good model outputs when moderate-to-low (<10-15°) slope angles are involved. At these slope angles, multiple adjacent DEM cell elevation values are equal due to the need for the DEM to approximate the low slope with a limited set of integer values for elevation. The first derivative of the elevation surface thus becomes zero. In these cases, flow propagation is inhibited by these spurious zero-slope conditions. Here we present evidence for this "terracing effect" from 1) a mathematically defined simulated elevation model, to demonstrate the terracing effects of integer valued data, and 2) a real-world DEM where terracing must be

  3. Vehicle Detection and Classification from High Resolution Satellite Images

    Science.gov (United States)

    Abraham, L.; Sasikumar, M.

    2014-11-01

    In the past decades satellite imagery has been used successfully for weather forecasting, geographical and geological applications. Low resolution satellite images are sufficient for these sorts of applications. But the technological developments in the field of satellite imaging provide high resolution sensors which expands its field of application. Thus the High Resolution Satellite Imagery (HRSI) proved to be a suitable alternative to aerial photogrammetric data to provide a new data source for object detection. Since the traffic rates in developing countries are enormously increasing, vehicle detection from satellite data will be a better choice for automating such systems. In this work, a novel technique for vehicle detection from the images obtained from high resolution sensors is proposed. Though we are using high resolution images, vehicles are seen only as tiny spots, difficult to distinguish from the background. But we are able to obtain a detection rate not less than 0.9. Thereafter we classify the detected vehicles into cars and trucks and find the count of them.

  4. High resolution SPM imaging of organic molecules with functionalized tips

    Science.gov (United States)

    Jelínek, Pavel

    2017-08-01

    One of the most remarkable and exciting achievements in the field of scanning probe microscopy (SPM) in the last years is the unprecedented sub-molecular resolution of both atomic and electronic structures of single molecules deposited on solid state surfaces. Despite its youth, the technique has already brought many new possibilities to perform different kinds of measurements, which cannot be accomplished by other techniques. This opens new perspectives in advanced characterization of physical and chemical processes and properties of molecular structures on surfaces. Here, we discuss the history and recent progress of the high resolution imaging with a functionalized probe by means of atomic force microscopy (AFM), scanning tunnelling microscopy (STM) and inelastic electron tunneling spectroscopy (IETS). We describe the mechanisms responsible for the high-resolution AFM, STM and IETS-STM contrast. The complexity of this technique requires new theoretical approaches, where a relaxation of the functionalized probe is considered. We emphasise the similarities of the mechanism driving high-resolution SPM with other imaging methods. We also summarise briefly significant achievements and progress in different branches. Finally we provide brief perspectives and remaining challenges of the further refinement of these high-resolution methods.

  5. High resolution magnetic imaging: MicroSQUID Force Microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Hasselbach, K; Ladam, C; Dolocan, V O; Hykel, D; Crozes, T [Institut Neel, CNRS et Universite Joseph Fourier, BP 166, F-38042 Grenoble Cedex 9 (France); Schuster, K [Institut de RadioAstronomie Millimetrique 300 rue de la Piscine, Domaine Universitaire F-38406 Saint Martin d' Heres (France); Mailly, D [Laboratoire de Photonique et de Nanostructures, CNRS, Site Alcatel de Marcoussis Route de Nozay F-91460 Marcoussis (France)], E-mail: klaus.hasselbach@grenoble.cnrs.fr

    2008-02-01

    Magnetic imaging at the micrometer scale with high sensitivity is a challenge difficult to be met. Magnetic force microscopy has a very high spatial resolution but is limited in magnetic resolution. Hall probe microscopy is very powerful but sensor fabrication at the one micron scale is difficult and effects due to discreteness of charge appear in the form of significant 1/f noise. SQUID microscopy is very powerful, having high magnetic resolution, but spatial resolution is usually of the order of 10 {mu}m. The difficulties lay mostly in an efficient way to couple flux to the sensor. The only way to improve spatial resolution is to place the probe close to the very edge of the support, thus maximising coupling and spatial resolution. If there has been found a way to bring close the tip, there must be also found a reliable a way to maintain distance during scanning. We want to present recent improvements on scanning microsquid microscopy: Namely the improved fabrication of microSQUID tips using silicon micro machining and the precise positioning of the micrometer diameter microSQUID loop by electron beam lithography. The microSQUID is a microbridge DC SQUID, with two opposite microbridges. The constrictions are patterned by high-resolution e-beam lithography and have a width of 20 nm and a length of about 100 nm. The distance control during scanning is obtained by integrating the microSQUID sensor with a piezoelectric tuning fork acting as a force sensor allowing to control height and even topographic imaging. The detector is placed in a custom built near field microscope and the sample temperature can be varied between 0.1 Kelvin and 10 K. The microscope is used to study magnetic flux structures in unconventional superconductors and will be used to observe thermal domains in superconducting detectors in the voltage state.

  6. Feasibility of a novel design of high resolution parallax-free Compton enhanced PET scanner dedicated to brain research

    Energy Technology Data Exchange (ETDEWEB)

    Braem, A [CERN, PH Department, CH-1211 Geneva (Switzerland); Llatas, M Chamizo [Department of Corpuscular and Nuclear Physics, Geneva University, Geneva (Switzerland); Chesi, E [CERN, PH Department, CH-1211 Geneva (Switzerland); Correia, J G [Instituto Tecnologico e Nuclear, Sacavem (Portugal); Garibaldi, F [Instituto Superiore di Sanita, Roma (Italy); Joram, C [CERN, PH Department, CH-1211 Geneva (Switzerland); Mathot, S [CERN, PH Department, CH-1211 Geneva (Switzerland); Nappi, E [INFN, Sezione di Bari, Bari (Italy); Silva, M Ribeiro da [Centro de FIsica Nuclear da Universidade de Lisboa, Lisbon (Portugal); Schoenahl, F [Division of Nuclear Medicine, Geneva University Hospital, CH-1211 Geneva (Switzerland); Seguinot, J [CERN, PH Department, CH-1211 Geneva (Switzerland); Weilhammer, P [CERN, PH Department, CH-1211 Geneva (Switzerland); Zaidi, H [Division of Nuclear Medicine, Geneva University Hospital, CH-1211 Geneva (Switzerland)

    2004-06-21

    A novel concept for a positron emission tomography (PET) camera module is proposed, which provides full 3D reconstruction with high resolution over the total detector volume, free of parallax errors. The key components are a matrix of long scintillator crystals and hybrid photon detectors (HPDs) with matched segmentation and integrated readout electronics. The HPDs read out the two ends of the scintillator package. Both excellent spatial (x, y, z) and energy resolution are obtained. The concept allows enhancing the detection efficiency by reconstructing a significant fraction of events which underwent Compton scattering in the crystals. The proof of concept will first be demonstrated with yttrium orthoaluminate perovskite (YAP):Ce crystals, but the final design will rely on other scintillators more adequate for PET applications (e.g. LSO:Ce or LaBr{sub 3}:Ce). A promising application of the proposed camera module, which is currently under development, is a high resolution 3D brain PET camera with an axial field-of-view of {approx}15 cm dedicated to brain research. The design philosophy and performance predictions based on analytical calculations and Monte Carlo simulations are presented. Image correction and reconstruction tools required to operate this transmissionless device in a research environment are also discussed. Better or similar performance parameters were obtained compared to other known designs at lower fabrication cost. The axial geometrical concept also seems to be promising for applications such as positron emission mammography.

  7. Feasibility of a novel design of high resolution parallax-free Compton enhanced PET scanner dedicated to brain research

    Science.gov (United States)

    Braem, A.; Chamizo Llatas, M.; Chesi, E.; Correia, J. G.; Garibaldi, F.; Joram, C.; Mathot, S.; Nappi, E.; Ribeiro da Silva, M.; Schoenahl, F.; Séguinot, J.; Weilhammer, P.; Zaidi, H.

    2004-06-01

    A novel concept for a positron emission tomography (PET) camera module is proposed, which provides full 3D reconstruction with high resolution over the total detector volume, free of parallax errors. The key components are a matrix of long scintillator crystals and hybrid photon detectors (HPDs) with matched segmentation and integrated readout electronics. The HPDs read out the two ends of the scintillator package. Both excellent spatial (x, y, z) and energy resolution are obtained. The concept allows enhancing the detection efficiency by reconstructing a significant fraction of events which underwent Compton scattering in the crystals. The proof of concept will first be demonstrated with yttrium orthoaluminate perovskite (YAP):Ce crystals, but the final design will rely on other scintillators more adequate for PET applications (e.g. LSO:Ce or LaBr3:Ce). A promising application of the proposed camera module, which is currently under development, is a high resolution 3D brain PET camera with an axial field-of-view of ~15 cm dedicated to brain research. The design philosophy and performance predictions based on analytical calculations and Monte Carlo simulations are presented. Image correction and reconstruction tools required to operate this transmissionless device in a research environment are also discussed. Better or similar performance parameters were obtained compared to other known designs at lower fabrication cost. The axial geometrical concept also seems to be promising for applications such as positron emission mammography. All the authors are members of the CIMA Collaboration.

  8. High spatial resolution diffusion tensor imaging and its applications

    CERN Document Server

    Wang, J J

    2002-01-01

    Introduction Magnetic Resonance Imaging is at present the only imaging technique available to measure diffusion of water and metabolites in humans. It provides vital insights to brain connectivity and has proved to be an important tool in diagnosis and therapy planning in many neurological diseases such as brain tumour, ischaemia and multiple sclerosis. This project focuses on the development of a high resolution diffusion tensor imaging technique. In this thesis, the basic theory of diffusion tensor MR Imaging is presented. The technical challenges encountered during development of these techniques will be discussed, with proposed solutions. New sequences with high spatial resolution have been developed and the results are compared with the standard technique more commonly used. Overview The project aims at the development of diffusion tensor imaging techniques with a high spatial resolution. Chapter 2 will describe the basic physics of MRI, the phenomenon of diffusion and the measurement of diffusion by MRI...

  9. Developing Visual Editors for High-Resolution Haptic Patterns

    DEFF Research Database (Denmark)

    Cuartielles, David; Göransson, Andreas; Olsson, Tony;

    2012-01-01

    In this article we give an overview of our iterative work in developing visual editors for creating high resolution haptic patterns to be used in wearable, haptic feedback devices. During the past four years we have found the need to address the question of how to represent, construct and edit hi...... resolution haptic patterns so that they translate naturally to the user’s haptic experience. To solve this question we have developed and tested several visual editors......In this article we give an overview of our iterative work in developing visual editors for creating high resolution haptic patterns to be used in wearable, haptic feedback devices. During the past four years we have found the need to address the question of how to represent, construct and edit high...

  10. A high resolution powder diffractometer using focusing optics

    Indian Academy of Sciences (India)

    V Siruguri; P D Babu; M Gupta; A V Pimpale; P S Goyal

    2008-11-01

    In this paper, we describe the design, construction and performance of a new high resolution neutron powder diffractometer that has been installed at the Dhruva reactor, Trombay, India. The instrument employs novel design concepts like the use of bent, perfect crystal monochromator and open beam geometry, enabling the use of smaller samples. The resolution curve of the instrument was found to have little variation over a wide angular region and a / ∼ 0.3% has been achieved. The instrument provides sample environment of very low temperatures and high magnetic fields using a 7 Tesla cryogen-free superconducting magnet with a VTI having a temperature range of 1.5–320 K. The special sample environment and high resolution make this neutron powder diffractometer a very powerful facility for studying magnetic properties of materials.

  11. The appearances of oesophageal carcinoma demonstrated on high-resolution, T2-weighted MRI, with histopathological correlation

    Energy Technology Data Exchange (ETDEWEB)

    Riddell, A.M. [Royal Marsden Hospital NHS Foundation Trust, Department of Radiology, London (United Kingdom); Royal Marsden Hospital NHS Foundation Trust, GI Oncology Imaging Research Fellow, Department of Diagnostic Imaging, London (United Kingdom); Allum, W.H.; Thompson, J.N. [Royal Marsden Hospital NHS Foundation Trust, Department of Surgery, London (United Kingdom); Wotherspoon, A.C. [Royal Marsden Hospital NHS Foundation Trust, Department of Histopathology, London (United Kingdom); Richardson, C.; Brown, G. [Royal Marsden Hospital NHS Foundation Trust, Department of Radiology, London (United Kingdom)

    2007-02-15

    This paper describes the spectrum of imaging features of oesophageal adenocarcinoma seen using high-resolution T2-weighted (T2W) magnetic resonance imaging (MRI). Thirty-nine patients with biopsy-proven oesophageal adenocarcinoma were scanned using an external surface coil. A sagittal T2W sequence was used to localise the tumour and to plan axial images perpendicular to the tumour. Fast spin-echo (FSE) T2W axial sequence parameters were: TR/TE, 3,300-5,000 ms/120-80 ms; field of view (FOV) 225 mm, matrix 176 x 512(reconstructed) mm to 256 x 224 mm, giving an in-plane resolution of between 1.28 x 0.44 mm and 0.88 x 1.00 mm, with 3-mm slice thickness. Thirty-three patients underwent resection and the MR images were compared with the histological whole-mount sections. There were four T1, 12 T2, and 17 T3 tumours. The T2W high-resolution MRI sequences produced detailed images of the oesophageal wall and surrounding structures. Analysis of the imaging appearances for different tumour T stages enabled the development of imaging criteria for local staging of oesophageal cancer using high-resolution MRI. Our study illustrates the spectrum of appearances of oesophageal cancer on T2W high-resolution MRI, and using the criteria established in this study, demonstrates the potential of this technique as an alternative non-invasive method for local staging for oesophageal cancer. (orig.)

  12. High-resolution corneal topography and tomography of fish eye using wide-field white light interference microscopy

    Science.gov (United States)

    Srivastava, Vishal; Nandy, Sreyankar; Singh Mehta, Dalip

    2013-04-01

    Topography and tomography of fish cornea is reconstructed using high resolution white light interference microscopy. White light interferograms at different depths were recorded by moving the object axially. For each depth position, five phase shifted interferograms were recorded and analyzed. From the reconstructed phase maps, the corneal topography and hence the refractive index was determined and from amplitude images the cross-sectional image of fish cornea was reconstructed. In the present method, we utilize a nearly common-path interference microscope and wide field illumination and hence do not require any mechanical B-scan. Therefore, the phase stability of the recorded data is improved.

  13. High-resolution low-dose scanning transmission electron microscopy.

    Science.gov (United States)

    Buban, James P; Ramasse, Quentin; Gipson, Bryant; Browning, Nigel D; Stahlberg, Henning

    2010-01-01

    During the past two decades instrumentation in scanning transmission electron microscopy (STEM) has pushed toward higher intensity electron probes to increase the signal-to-noise ratio of recorded images. While this is suitable for robust specimens, biological specimens require a much reduced electron dose for high-resolution imaging. We describe here protocols for low-dose STEM image recording with a conventional field-emission gun STEM, while maintaining the high-resolution capability of the instrument. Our findings show that a combination of reduced pixel dwell time and reduced gun current can achieve radiation doses comparable to low-dose TEM.

  14. Novel techniques in VUV high-resolution spectroscopy

    CERN Document Server

    Ubachs, W; Eikema, K S E; de Oliveira, N; Nahon, L

    2013-01-01

    Novel VUV sources and techniques for VUV spectroscopy are reviewed. Laser-based VUV sources have been developed via non-linear upconversion of laser pulses in the nanosecond (ns), the picosecond (ps), and femtosecond (fs) domain, and are applied in high-resolution gas phase spectroscopic studies. While the ns and ps pulsed laser sources, at Fourier-transform limited bandwidths, are used in wavelength scanning spectroscopy, the fs laser source is used in a two-pulse time delayed mode. In addition a Fourier-transform spectrometer for high resolution gas-phase spectroscopic studies in the VUV is described, exhibiting the multiplex advantage to measure many resonances simultaneously.

  15. Progress in high-resolution x-ray holographic microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Jacobsen, C.; Kirz, J.; Howells, M.; McQuaid, K.; Rothman, S.; Feder, R.; Sayre, D.

    1987-07-01

    Among the various types of x-ray microscopes that have been demonstrated, the holographic microscope has had the largest gap between promise and performance. The difficulties of fabricating x-ray optical elements have led some to view holography as the most attractive method for obtaining the ultimate in high resolution x-ray micrographs; however, we know of no investigations prior to 1987 that clearly demonstrated submicron resolution in reconstructed images. Previous efforts suffered from problems such as limited resolution and dynamic range in the recording media, low coherent x-ray flux, and aberrations and diffraction limits in visible light reconstruction. We have addressed the recording limitations through the use of an undulator x-ray source and high-resolution photoresist recording media. For improved results in the readout and reconstruction steps, we have employed metal shadowing and transmission electron microscopy, along with numerical reconstruction techniques. We believe that this approach will allow holography to emerge as a practical method of high-resolution x-ray microscopy. 30 refs., 4 figs.

  16. High-resolution EEG (HR-EEG) and magnetoencephalography (MEG).

    Science.gov (United States)

    Gavaret, M; Maillard, L; Jung, J

    2015-03-01

    High-resolution EEG (HR-EEG) and magnetoencephalography (MEG) allow the recording of spontaneous or evoked electromagnetic brain activity with excellent temporal resolution. Data must be recorded with high temporal resolution (sampling rate) and high spatial resolution (number of channels). Data analyses are based on several steps with selection of electromagnetic signals, elaboration of a head model and use of algorithms in order to solve the inverse problem. Due to considerable technical advances in spatial resolution, these tools now represent real methods of ElectroMagnetic Source Imaging. HR-EEG and MEG constitute non-invasive and complementary examinations, characterized by distinct sensitivities according to the location and orientation of intracerebral generators. In the presurgical assessment of drug-resistant partial epilepsies, HR-EEG and MEG can characterize and localize interictal activities and thus the irritative zone. HR-EEG and MEG often yield significant additional data that are complementary to other presurgical investigations and particularly relevant in MRI-negative cases. Currently, the determination of the epileptogenic zone and functional brain mapping remain rather less well-validated indications. In France, in 2014, HR-EEG is now part of standard clinical investigation of epilepsy, while MEG remains a research technique.

  17. High-Resolution AUV Mapping Reveals Structural Details of Submarine Inflated Lava Flows

    Science.gov (United States)

    Paduan, J.; Clague, D. A.; Caress, D. W.; Thomas, H.; Thompson, D.; Conlin, D.

    2009-12-01

    The MBARI mapping AUV D. Allan B. has now been used to map volcanic terrain at mid-ocean ridges, back-arc spreading centers, and seamounts. These include the summit caldera and upper south rift zone at Axial Volcano, the summit of Davidson Seamount, the Endeavour hydrothermal fields, the Northeast Lau Spreading Center and West Mata Volcano, and, most recently, the CoAxial, North Cleft and North Gorda historic eruption sites on the Juan de Fuca and Gorda Ridges. ROV and submersible dives at most of these sites have provided groundtruth for the textures and features revealed in the roughly 1-m resolution maps. A prominent feature in the maps from four of the sites are inflated flows that did not deflate or drain. These resemble subaerial tumuli but differ in being located on level terrain, apparently atop or very near eruptive vents instead of being in the distal portions of flows. The largest inflated flow at Axial Volcano is on the caldera floor. The main part is 500 by 300 m, and up to 30 m high, with a lobe that extends another 750 m in a sinuous path. It and two nearby, medium-sized inflated flows were first described from sidescan imagery and a submersible dive by Appelgate and Embley (Bull. Volcanol., 54, 447-458, 1992). The AUV maps show clearly the smooth, gently domed relief of the large inflated flow and its sinuous shape on the seafloor, the medium-sized nearby inflated flows, and several additional smaller ones. Particularly striking is a network of 4 to 10 m deep cracks along the crest of each inflation. The cracks occur 30 to 50 m from the margins on all sides of the wider parts of the inflated flows, and become medial cracks along the entire length of the narrow parts, which are nearly triangular in cross-section. An inflation pit 35 m in diameter has a depth equal to the surrounding lava fields. ROV Doc Ricketts dove on these flows in August 2009 and photographed the deeply cracked, uplifted, once flat-lying lineated and ropy sheet flows that form

  18. Multi-resolution voxel phantom modeling: a high-resolution eye model for computational dosimetry

    Science.gov (United States)

    Caracappa, Peter F.; Rhodes, Ashley; Fiedler, Derek

    2014-09-01

    Voxel models of the human body are commonly used for simulating radiation dose with a Monte Carlo radiation transport code. Due to memory limitations, the voxel resolution of these computational phantoms is typically too large to accurately represent the dimensions of small features such as the eye. Recently reduced recommended dose limits to the lens of the eye, which is a radiosensitive tissue with a significant concern for cataract formation, has lent increased importance to understanding the dose to this tissue. A high-resolution eye model is constructed using physiological data for the dimensions of radiosensitive tissues, and combined with an existing set of whole-body models to form a multi-resolution voxel phantom, which is used with the MCNPX code to calculate radiation dose from various exposure types. This phantom provides an accurate representation of the radiation transport through the structures of the eye. Two alternate methods of including a high-resolution eye model within an existing whole-body model are developed. The accuracy and performance of each method is compared against existing computational phantoms.

  19. Axial growth in high Zircaloy-4 structural components due to the hydrogen incorporation; Crecimiento axial de componentes de Zircaloy-4 debido a la incorporacion de hidrogeno

    Energy Technology Data Exchange (ETDEWEB)

    Fagundez, Cintia P.; Vizcaino, Pablo; Bianchi, Daniel; Banchik, Abraham D. [Comision Nacional de Energia Atomica (CNEA), Buenos Aires (Argentina). Centro Atomico Ezeiza. Lab. de Materiales Planta Piloto de Fabricacion de Aleaciones Especiales]. E-mail: fagundez@cnea.gov.ar; vizcaino@cae.cnea.gov.ar; banchik@cae.cnea.gov.ar; dbianchi@cae.cnea.gov.ar

    2005-07-01

    The zirconium based structural components under the severe operation conditions experiment changes in theirs original dimensions. These dimensional changes may be attributed to two causes: hydrogen incorporation and irradiation growth. Both causes play a role in the dimensional changes but only the reactor- in conditions can define if the two or one of them is significant. In structural components as the pressure tubes of the CANDU type reactors, where hydrogen content is less than forty ppm are acceptable, changes due to hydrogen incorporation are irrelevant. But in the case of the six meters long cooling channels of the Atucha 1 (CNA-1) nuclear power reactor, where hydrogen content up to 1000 ppm are possible, the situation could be different. In the present work the attention was focused on the volume changes due to the hydrogen incorporation. When the terminal solid solubility limit is exceeded in the zirconium based alloys, the hydride precipitation occurs. In Zircaloy-4 at the operating temperature, 300 deg C, about 90 ppm are in solid solution and the rest is precipitated as hydrides. Both situations produce a positive volume change which contributes to the growth. In this work the dimensional change produced by hydrogen incorporation in the CNA-1's channels was estimated. The expansion due to hydrogen absorption and the change of length caused by hydride dissolution and precipitation were measured by differential dilatometry in samples with hydrogen contents ranging from 20 to 650 ppm. The dilatometric data indicates that in the cooling channels of the CNA1, the axial growth is linear with the hydrogen concentration, and the calculated growing rate is 1,87 x 10-6 mm/mm material {sup *}ppm H. This rate for the upper hydrogen concentration limit of the channels implies a growth of 6,08 mm. As an accuracy testing method for the applied technique, the terminal solid solubility curve was determined by both, differential dilatometry and differential scanning

  20. Development of high-performance and low-noise axial-flow fan units in their local operating region

    Energy Technology Data Exchange (ETDEWEB)

    Heo, Seung; Ha, Min Ho; Cheong, Cheol Ung [Pusan National University, Busan (Korea, Republic of); Kim, Tae Hoon [LG Electronics Inc., Changwon (Korea, Republic of)

    2015-09-15

    Aerodynamic and aeroacoustic performances of an axial-flow fan unit are improved by modifying its housing structure without changing the fan blade. The target axial-flow fan system is used to lower temperature of a compressor and a condenser in the machine room of a household refrigerator which has relatively high system resistance due to complex layout of structures inside it. First, the performance of the fan system is experimentally characterized by measuring its volume flow rate versus static pressure using a fan performance tester satisfying the AMCA (Air Movement and Control Association) regulation, AMCA 210-07. The detailed structure of flow driven by the fan is numerically investigated using a virtual fan performance tester based on computational fluid dynamics techniques. The prediction result reveals possible loss due to radial and tangential velocity components in the wake flow downstream of the fan. The length of the fan housing is chosen as a design parameter for improving the aerodynamic and aeroacoustic performances of the fan unit by reducing the identified radial and tangential velocity components. Three fan units with different housing lengths longer than the original are analyzed using the virtual fan performance tester. The results confirm the improved aerodynamic performance of the proposed three designs. The flow field driven by the proposed fan unit is closely examined to find the causes for the observed performance improvements, which ensures that the radial and tangential velocity components in the wake flow are reduced. Finally, the improved performance of the proposed fan systems is validated by comparing the P-Q and efficiency curves measured using the fan performance tester. The noise emission from the household refrigerator is also found to be lessened when the new fan units are installed.

  1. High-resolution imaging of biological tissue with full-field optical coherence tomography

    Science.gov (United States)

    Zhu, Yue; Gao, Wanrong

    2015-03-01

    A new full-field optical coherence tomography system with high-resolution has been developed for imaging of cells and tissues. Compared with other FF-OCT (Full-field optical coherence tomography, FF-OCT) systems illuminated with optical fiber bundle, the improved Köhler illumination arrangement with a halogen lamp was used in the proposed FF-OCT system. High numerical aperture microscopic objectives were used for imaging and a piezoelectric ceramic transducer (PZT) was used for phase-shifting. En-face tomographic images can be obtained by applying the five-step phase-shifting algorithm to a series of interferometric images which are recorded by a smart camera. Three-dimensional images can be generated from these tomographic images. Imaging of the chip of Intel Pentium 4 processor demonstrated the ultrahigh resolution of the system (lateral resolution is 0.8μm ), which approaches the theoretical resolution 0.7 μm× 0.5 μm (lateral × axial). En-face images of cells of onion show an excellent performance of the system in generating en-face images of biological tissues. Then, unstained pig stomach was imaged as a tissue and gastric pits could be easily recognized using FF-OCT system. Our study provides evidence for the potential ability of FFOCT in identifying gastric pits from pig stomach tissue. Finally, label-free and unstained ex vivo human liver tissues from both normal and tumor were imaged with this FFOCT system. The results show that the setup has the potential for medical diagnosis applications such liver cancer diagnosis.

  2. High Resolution Simulations of Future Climate in West Africa Using a Variable-Resolution Atmospheric Model

    Science.gov (United States)

    Adegoke, J. O.; Engelbrecht, F.; Vezhapparambu, S.

    2013-12-01

    In previous work demonstrated the application of a var¬iable-resolution global atmospheric model, the conformal-cubic atmospheric model (CCAM), across a wide range of spatial and time scales to investigate the ability of the model to provide realistic simulations of present-day climate and plausible projections of future climate change over sub-Saharan Africa. By applying the model in stretched-grid mode the versatility of the model dynamics, numerical formulation and physical parameterizations to function across a range of length scales over the region of interest, was also explored. We primarily used CCAM to illustrate the capability of the model to function as a flexible downscaling tool at the climate-change time scale. Here we report on additional long term climate projection studies performed by downscaling at much higher resolutions (8 Km) over an area that stretches from just south of Sahara desert to the southern coast of the Niger Delta and into the Gulf of Guinea. To perform these simulations, CCAM was provided with synoptic-scale forcing of atmospheric circulation from 2.5 deg resolution NCEP reanalysis at 6-hourly interval and SSTs from NCEP reanalysis data uses as lower boundary forcing. CCAM 60 Km resolution downscaled to 8 Km (Schmidt factor 24.75) then 8 Km resolution simulation downscaled to 1 Km (Schmidt factor 200) over an area approximately 50 Km x 50 Km in the southern Lake Chad Basin (LCB). Our intent in conducting these high resolution model runs was to obtain a deeper understanding of linkages between the projected future climate and the hydrological processes that control the surface water regime in this part of sub-Saharan Africa.

  3. High resolution spectroscopy in the microwave and far infrared

    Science.gov (United States)

    Pickett, Herbert M.

    1990-01-01

    High resolution rotational spectroscopy has long been central to remote sensing techniques in atmospheric sciences and astronomy. As such, laboratory measurements must supply the required data to make direct interpretation of data for instruments which sense atmospheres using rotational spectra. Spectral measurements in the microwave and far infrared regions are also very powerful tools when combined with infrared measurements for characterizing the rotational structure of vibrational spectra. In the past decade new techniques were developed which have pushed high resolution spectroscopy into the wavelength region between 25 micrometers and 2 mm. Techniques to be described include: (1) harmonic generation of microwave sources, (2) infrared laser difference frequency generation, (3) laser sideband generation, and (4) ultrahigh resolution interferometers.

  4. High resolution map of light pollution over Poland

    Science.gov (United States)

    Netzel, Henryka; Netzel, Paweł

    2016-09-01

    In 1976 Berry introduced a simple mathematical equation to calculate artificial night sky brightness at zenith. In the original model cities, considered as points with given population, are only sources of light emission. In contrary to Berry's model, we assumed that all terrain surface can be a source of light. Emission of light depends on percent of built up area in a given cell. We based on Berry's model. Using field measurements and high-resolution data we obtained the map of night sky brightness over Poland in 100-m resolution. High resolution input data, combined with a very simple model, makes it possible to obtain detailed structures of the night sky brightness without complicating the calculations.

  5. A cloud mask methodology for high resolution remote sensing data combining information from high and medium resolution optical sensors

    Science.gov (United States)

    Sedano, Fernando; Kempeneers, Pieter; Strobl, Peter; Kucera, Jan; Vogt, Peter; Seebach, Lucia; San-Miguel-Ayanz, Jesús

    2011-09-01

    This study presents a novel cloud masking approach for high resolution remote sensing images in the context of land cover mapping. As an advantage to traditional methods, the approach does not rely on thermal bands and it is applicable to images from most high resolution earth observation remote sensing sensors. The methodology couples pixel-based seed identification and object-based region growing. The seed identification stage relies on pixel value comparison between high resolution images and cloud free composites at lower spatial resolution from almost simultaneously acquired dates. The methodology was tested taking SPOT4-HRVIR, SPOT5-HRG and IRS-LISS III as high resolution images and cloud free MODIS composites as reference images. The selected scenes included a wide range of cloud types and surface features. The resulting cloud masks were evaluated through visual comparison. They were also compared with ad-hoc independently generated cloud masks and with the automatic cloud cover assessment algorithm (ACCA). In general the results showed an agreement in detected clouds higher than 95% for clouds larger than 50 ha. The approach produced consistent results identifying and mapping clouds of different type and size over various land surfaces including natural vegetation, agriculture land, built-up areas, water bodies and snow.

  6. PHASE-ONLY OPTICAL PUPIL FILTER FOR IMPROVING AXIAL RESOLUTION IN CONFOCAL MICROSCOPY%改善共焦系统轴向分辨率的位相型光瞳滤波器

    Institute of Scientific and Technical Information of China (English)

    刘力; 邓小强; 王桂英; 徐至展

    2001-01-01

    In this paper, two kinds of 3-zone phase-only pupil filter for confocal microscopy were optimally designed with constrained global optimization(CGO)algorithm. The CGO method is discussed in detail. The first kind of pupil filter can increase the axial resolution while unchanging the transverse resolution, which can improve the optical-sectioning capacity in confocal microscopy. The second kind of pupil filter can increase the axial and transverse resolution at the same time, which is applicable in 3-dimensional imaging in confocal microscopy.%利用约束全局优化算法——CGO算法,设计了两种用于共焦系统的三区位相型光瞳滤波器.第一种滤波器在不改变系统的横向分辨率的同时,可以大幅度地提高轴向分辨率,提高了系统的层析能力.第二种滤波器在提高系统轴向分辨率的同时,又能提高其横向分辨率,适用于系统的三维成像.

  7. High-resolution TFT-LCD for spatial light modulator

    Science.gov (United States)

    Lee, JaeWon; Kim, Yong-Hae; Byun, Chun-Won; Pi, Jae-Eun; Oh, Himchan; Kim, GiHeon; Lee, Myung-Lae; Chu, Hye-Yong; Hwang, Chi-Sun

    2014-06-01

    SLM with very fine pixel pitch is needed for the holographic display system. Among various kinds of SLMs, commercially available high resolution LCoS has been widely used as a spatial light modulator. But the size of commercially available LCoS SLM is limited because the manufacturing technology of LCoS is based on the semiconductor process developed on small size Si wafer. Recently very high resolution flat panel display panel (~500ppi) was developed as a "retina display". Until now, the pixel pitch of flat panel display is several times larger than the pixel pitch of LCoS. But considering the possibility of shrink down the pixel pitch with advanced lithographic tools, the application of flat panel display will make it possible to build a SLM with high spatial bandwidth product. We simulated High resolution TFT-LCD panel on glass substrate using oxide semiconductor TFT with pixel pitch of 20um. And we considered phase modulation behavior of LC(ECB) mode. The TFT-LCD panel is reflective type with 4-metal structure with organic planarization layers. The technical challenge for high resolution large area SLM will be discussed with very fine pixel.

  8. High resolution multiplexed functional imaging in live embryos (Conference Presentation)

    Science.gov (United States)

    Xu, Dongli; Zhou, Weibin; Peng, Leilei

    2017-02-01

    Fourier multiplexed fluorescence lifetime imaging (FmFLIM) scanning laser optical tomography (FmFLIM-SLOT) combines FmFLIM and Scanning laser optical tomography (SLOT) to perform multiplexed 3D FLIM imaging of live embryos. The system had demonstrate multiplexed functional imaging of zebrafish embryos genetically express Foster Resonant Energy Transfer (FRET) sensors. However, previous system has a 20 micron resolution because the focused Gaussian beam diverges quickly from the focused plane, makes it difficult to achieve high resolution imaging over a long projection depth. Here, we present a high-resolution FmFLIM-SLOT system with achromatic Bessel beam, which achieves 3 micron resolution in 3D deep tissue imaging. In Bessel-FmFLIM-SLOT, multiple laser excitation lines are firstly intensity modulated by a Michelson interferometer with a spinning polygon mirror optical delay line, which enables Fourier multiplexed multi-channel lifetime measurements. Then, a spatial light modulator and a prism are used to transform the modulated Gaussian laser beam to an achromatic Bessel beam. The achromatic Bessel beam scans across the whole specimen with equal angular intervals as sample rotated. After tomography reconstruction and the frequency domain lifetime analysis method, both the 3D intensity and lifetime image of multiple excitation-emission can be obtained. Using Bessel-FmFLIM-SLOT system, we performed cellular-resolution FLIM tomography imaging of live zebrafish embryo. Genetically expressed FRET sensors in these embryo will allow non-invasive observation of multiple biochemical processes in vivo.

  9. High-resolution 3D reconstruction of microtubule structures by quantitative multi-angle total internal reflection fluorescence microscopy

    Science.gov (United States)

    Jin, Luhong; Wu, Jian; Xiu, Peng; Fan, Jiannan; Hu, Miao; Kuang, Cuifang; Xu, Yingke; Zheng, Xiaoxiang; Liu, Xu

    2017-07-01

    Total internal reflection fluorescence microscopy (TIRFM) has been widely used in biomedical research to visualize cellular processes near the cell surface. In this study, a novel multi-angle ring-illuminated TIRFM system, equipped with two galvo mirrors that are on conjugate plan of a 4f optical system was developed. Multi-angle TIRFM generates images with different penetration depths through the controlled variation of the incident angle of illuminating laser. We presented a method to perform three-dimensional (3-D) reconstruction of microtubules from multi-angle TIRFM images. The performance of our method was validated in simulated microtubules with variable signal-to-noise ratios (SNR) and the axial resolution and accuracy of reconstruction were evaluated in selecting different numbers of illumination angles or in different SNR conditions. In U373 cells, we reconstructed the 3-D localization of microtubules near the cell surface with high resolution using over a hundred different angles. Theoretically, the presented TIRFM setup and 3-D reconstruction method can achieve 40 nm axial resolution in experimental conditions where SNR is as low as 2, with 35 different illumination angles. Moreover, our system and reconstruction method have the potential to be used in live cells to track membrane dynamics in 3-D.

  10. Immersion Gratings for Infrared High-resolution Spectroscopy

    Science.gov (United States)

    Sarugaku, Yuki; Ikeda, Yuji; Kobayashi, Naoto; Kaji, Sayumi; Sukegawa, Takashi; Sugiyama, Shigeru; Nakagawa, Takao; Arasaki, Takayuki; Kondo, Sohei; Nakanishi, Kenshi; Yasui, Chikako; Kawakita, Hideyo

    2016-10-01

    High-resolution spectroscopy in the infrared wavelength range is essential for observations of minor isotopologues, such as HDO for water, and prebiotic organic molecules like hydrocarbons/P-bearing molecules because numerous vibrational molecular bands (including non-polar molecules) are located in this wavelength range. High spectral resolution enables us to detect weak lines without spectral line confusion. This technique has been widely used in planetary sciences, e.g., cometary coma (H2O, CO, and organic molecules), the martian atmosphere (CH4, CO2, H2O and HDO), and the upper atmosphere of gas giants (H3+ and organic molecules such as C2H6). Spectrographs with higher resolution (and higher sensitivity) still have a potential to provide a plenty of findings. However, because the size of spectrographs scales with the spectral resolution, it is difficult to realize it.Immersion grating (IG), which is a diffraction grating wherein the diffraction surface is immersed in a material with a high refractive index (n > 2), provides n times higher spectral resolution compared to a reflective grating of the same size. Because IG reduces the size of spectrograph to 1/n compared to the spectrograph with the same spectral resolution using a conventional reflective grating, it is widely acknowledged as a key optical device to realize compact spectrographs with high spectral resolution.Recently, we succeeded in fabricating a CdZnTe immersion grating with the theoretically predicted diffraction efficiency by machining process using an ultrahigh-precision five-axis processing machine developed by Canon Inc. Using the same technique, we completed a practical germanium (Ge) immersion grating with both a reflection coating on the grating surface and the an AR coating on the entrance surface. It is noteworthy that the wide wavelength range from 2 to 20 um can be covered by the two immersion gratings.In this paper, we present the performances and the applications of the immersion

  11. High-resolution polarization sensitive OCT for ocular imaging in rodents

    Science.gov (United States)

    Fialová, Stanislava; Rauscher, Sabine; Gröger, Marion; Pircher, Michael; Hitzenberger, Christoph K.; Baumann, Bernhard

    2015-03-01

    A new high-resolution polarization sensitive optical coherence tomography system was developed for imaging rodent retina. Various light-tissue interactions such as birefringence and depolarization can change the polarization state of light. In the eye, there are several tissues that have these properties, for example retinal pigment epithelium (depolarization) and sclera (birefringence). These layers play key roles in diseases like age-related macular degeneration or glaucoma. Animal models are an important component for understanding disease pathogenesis. The gold standard for the evaluation of preclinical experiments is histology, which is an invasive and terminal procedure. Since OCT is non-invasive, it has the potential to be an alternative to histology with the benefit of long-term study of the disease progression in the same animal. In this study, a superluminescent diode with spectrum width 100 nm and mean wavelength 840 nm is used as a light source in order to enable high axial resolution. Spectrometers are custom built to enable high imaging speed that allows acquiring 3D data sets with 1024x200x1536 voxels in 3.44 s. From the acquired data, images displaying phase retardation induced by birefringence and orientation of birefringent axis were calculated. In first measurements, we were able to identify the RPE-choroid complex (depolarization effect) and the sclera (strong birefringence) in the retina of Long-Evans and Sprague-Dawley rats. Our preliminary results demonstrate the feasibility of the system for high speed/resolution imaging of the rodent retina. This is useful for longitudinal studies of disease models of retinal disease in rats and mice

  12. A DVD Spectroscope: A Simple, High-Resolution Classroom Spectroscope

    Science.gov (United States)

    Wakabayashi, Fumitaka; Hamada, Kiyohito

    2006-01-01

    Digital versatile disks (DVDs) have successfully made up an inexpensive but high-resolution spectroscope suitable for classroom experiments that can easily be made with common material and gives clear and fine spectra of various light sources and colored material. The observed spectra can be photographed with a digital camera, and such images can…

  13. High-resolution kinetic energy distributions via doppler shift measurements

    Science.gov (United States)

    Xu, Z.; Koplitz, B.; Buelow, S.; Baugh, D.; Wittig, C.

    1986-07-01

    In photolysis/probe experiments using pulsed sources, time delay produces both spatial and directional bias in the fragment distributions, thus enabling well-resolved kinetic energy distributions to be obtained from Doppler shift measurements. Data are presented for H-atoms detected using two-photon ionization, and high S/N and laser-limited kinetic energy resolution are demonstrated.

  14. High resolution ultraviolet imaging spectrometer for latent image analysis.

    Science.gov (United States)

    Lyu, Hang; Liao, Ningfang; Li, Hongsong; Wu, Wenmin

    2016-03-21

    In this work, we present a close-range ultraviolet imaging spectrometer with high spatial resolution, and reasonably high spectral resolution. As the transmissive optical components cause chromatic aberration in the ultraviolet (UV) spectral range, an all-reflective imaging scheme is introduced to promote the image quality. The proposed instrument consists of an oscillating mirror, a Cassegrain objective, a Michelson structure, an Offner relay, and a UV enhanced CCD. The finished spectrometer has a spatial resolution of 29.30μm on the target plane; the spectral scope covers both near and middle UV band; and can obtain approximately 100 wavelength samples over the range of 240~370nm. The control computer coordinates all the components of the instrument and enables capturing a series of images, which can be reconstructed into an interferogram datacube. The datacube can be converted into a spectrum datacube, which contains spectral information of each pixel with many wavelength samples. A spectral calibration is carried out by using a high pressure mercury discharge lamp. A test run demonstrated that this interferometric configuration can obtain high resolution spectrum datacube. The pattern recognition algorithm is introduced to analyze the datacube and distinguish the latent traces from the base materials. This design is particularly good at identifying the latent traces in the application field of forensic imaging.

  15. A Large Scale, High Resolution Agent-Based Insurgency Model

    Science.gov (United States)

    2013-09-30

    2007). HSCB Models can be employed for simulating mission scenarios, determining optimal strategies for disrupting terrorist networks, or training and...High Resolution Agent-Based Insurgency Model ∑ = ⎜ ⎜ ⎝ ⎛ − −− = desired 1 move,desired, desired,,desired, desired,, N j ij jmoveij moveiD rp prp

  16. Workshop on high-resolution, large-acceptance spectrometers

    Energy Technology Data Exchange (ETDEWEB)

    Zeidman, B. (ed.)

    1981-01-01

    The purpose of the Workshop on High-Resolution, Large-Acceptance Spectrometers was to provide a means for exchange of information among those actively engaged in the design and construction of these new spectrometers. Thirty-seven papers were prepared for the data base.

  17. Remote parallel rendering for high-resolution tiled display walls

    KAUST Repository

    Nachbaur, Daniel

    2014-11-01

    © 2014 IEEE. We present a complete, robust and simple to use hardware and software stack delivering remote parallel rendering of complex geometrical and volumetric models to high resolution tiled display walls in a production environment. We describe the setup and configuration, present preliminary benchmarks showing interactive framerates, and describe our contributions for a seamless integration of all the software components.

  18. High resolution STEM of quantum dots and quantum wires

    DEFF Research Database (Denmark)

    Kadkhodazadeh, Shima

    2013-01-01

    This article reviews the application of high resolution scanning transmission electron microscopy (STEM) to semiconductor quantum dots (QDs) and quantum wires (QWRs). Different imaging and analytical techniques in STEM are introduced and key examples of their application to QDs and QWRs...

  19. Structure Identification in High-Resolution Transmission Electron Microscopic Images

    DEFF Research Database (Denmark)

    Vestergaard, Jacob Schack; Kling, Jens; Dahl, Anders Bjorholm

    2014-01-01

    A connection between microscopic structure and macroscopic properties is expected for almost all material systems. High-resolution transmission electron microscopy is a technique offering insight into the atomic structure, but the analysis of large image series can be time consuming. The present ...

  20. Signal Processing for High Resolution FMCW SAR and Moving Target

    NARCIS (Netherlands)

    Meta, A.; Hoogeboom, P.

    2005-01-01

    The combination of Frequency Modulated ContinuousWave (FMCW) technology and Synthetic Aperture Radar (SAR) leads to lightweight, cost-effective imaging sensors of high resolution. In FMCW SAR applications the conventional stop-and-go approximation used in pulse radar algorithms cannot be considered

  1. High Resolution Digital Imaging of Paintings: The Vasari Project.

    Science.gov (United States)

    Martinez, Kirk

    1991-01-01

    Describes VASARI (the Visual Art System for Archiving and Retrieval of Images), a project funded by the European Community to show the feasibility of high resolution colormetric imaging directly from paintings. The hardware and software used in the system are explained, storage on optical disks is described, and initial results are reported. (five…

  2. Ultra-high-resolution small-animal SPECT imaging

    NARCIS (Netherlands)

    Have, F. van der

    2007-01-01

    The main subject of this thesis is the development of the first two in a series of dedicated ultra-high resolution Single Photon Emission Computed Tomography (SPECT) systems (U-SPECT-I and II) for the imaging of distributions of radio-isotope labeled tracers in small laboratory animals such as mice

  3. HIGH RESOLUTION RESISTIVITY LEAK DETECTION DATA PROCESSING & EVALUATION MEHTODS & REQUIREMENTS

    Energy Technology Data Exchange (ETDEWEB)

    SCHOFIELD JS

    2007-10-04

    This document has two purposes: {sm_bullet} Describe how data generated by High Resolution REsistivity (HRR) leak detection (LD) systems deployed during single-shell tank (SST) waste retrieval operations are processed and evaluated. {sm_bullet} Provide the basic review requirements for HRR data when Hrr is deployed as a leak detection method during SST waste retrievals.

  4. High resolution ultrasonography in isolated soft tissue and intramuscular cysticercosis

    Directory of Open Access Journals (Sweden)

    Gaurav Sharma

    2016-01-01

    Conclusions: With the advent of high resolution ultrasonography and increased clinical awareness of the isolated soft tissue-intramuscular cysticercosis especially in endemic zone, a more conservative non-invasive approach can be applied both in diagnosis and treatment of these isolated cases of cysticercosis. [Int J Res Med Sci 2016; 4(1.000: 42-46

  5. Development of high accuracy and resolution geoid and gravity maps

    Science.gov (United States)

    Gaposchkin, E. M.

    1986-01-01

    Precision satellite to satellite tracking can be used to obtain high precision and resolution maps of the geoid. A method is demonstrated to use data in a limited region to map the geopotential at the satellite altitude. An inverse method is used to downward continue the potential to the Earth surface. The method is designed for both satellites in the same low orbit.

  6. Systematic high-resolution assessment of global hydropower potential

    NARCIS (Netherlands)

    Hoes, Olivier A C; Meijer, Lourens J J; Van Der Ent, Ruud J.; Van De Giesen, Nick C.

    2017-01-01

    Population growth, increasing energy demand and the depletion of fossil fuel reserves necessitate a search for sustainable alternatives for electricity generation. Hydropower could replace a large part of the contribution of gas and oil to the present energy mix. However, previous high-resolution

  7. High-resolution radio imaging of young supernovae

    CERN Document Server

    Pérez-Torres, M A; Alberdi, A; Ros, E; Guirado, J C; Lara, L; Mantovani, F; Stockdale, C J; Weiler, K W; Diamond, P J; Van Dyk, S D; Lundqvist, P; Panagia, N; Shapiro, I I; Sramek, R

    2004-01-01

    The high resolution obtained through the use of VLBI gives an unique opportunity to directly observe the interaction of an expanding radio supernova with its surrounding medium. We present here results from our VLBI observations of the young supernovae SN 1979C, SN 1986J, and SN 2001gd.

  8. High energy resolution off-resonant X-ray spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Wojciech, Blachucki [Univ. of Fribourg (Switzerland). Dept. of Physics

    2015-10-16

    This work treats of the high energy resolution off-resonant X-ray spectroscopy (HEROS) method of determining the density of unoccupied electronic states in the vicinity of the absorption edge. HEROS is an alternative to the existing X-ray absorption spectroscopy (XAS) methods and opens the way for new studies not achievable before.

  9. High-resolution palaeoclimatology of the last millennium

    DEFF Research Database (Denmark)

    Vinther, Bo Møllesøe; Jones, P.D.; Briffa, K.R.

    2009-01-01

    Palaeoclimatology • high-resolution • last millennium • tree rings • dendroclimatology • chronology • uncertainty • corals • ice-cores • speleothems • documentary evidence • instrumental records • varves • borehole temperature • marine sediments • composite plus scaling • CPS • climate field...

  10. Resolution of RNA using high-performance liquid chromatography

    NARCIS (Netherlands)

    Mclaughlin, L.W.; Bischoff, Rainer

    1987-01-01

    High-performance liquid chromatographic techniques can be very effective for the resolution and isolation of nucleic acids. The characteristic ionic (phosphodiesters) and hydrophobic (nucleobases) properties of RNAs can be exploited for their separation. In this respect anion-exchange and reversed-p

  11. Five Micron High Resolution MALDI Mass Spectrometry Imaging with Simple, Interchangeable, Multi-Resolution Optical System

    Science.gov (United States)

    Feenstra, Adam D.; Dueñas, Maria Emilia; Lee, Young Jin

    2017-01-01

    High-spatial resolution mass spectrometry imaging (MSI) is crucial for the mapping of chemical distributions at the cellular and subcellular level. In this work, we improved our previous laser optical system for matrix-assisted laser desorption ionization (MALDI)-MSI, from 9 μm practical laser spot size to a practical laser spot size of 4 μm, thereby allowing for 5 μm resolution imaging without oversampling. This is accomplished through a combination of spatial filtering, beam expansion, and reduction of the final focal length. Most importantly, the new laser optics system allows for simple modification of the spot size solely through the interchanging of the beam expander component. Using 10×, 5×, and no beam expander, we could routinely change between 4, 7, and 45 μm laser spot size, in less than 5 min. We applied this multi-resolution MALDI-MSI system to a single maize root tissue section with three different spatial resolutions of 5, 10, and 50 μm and compared the differences in imaging quality and signal sensitivity. We also demonstrated the difference in depth of focus between the optical systems with 10× and 5× beam expanders.

  12. Topography improvements in MEMS DMs for high-contrast, high-resolution imaging Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This project will develop and demonstrate an innovative microfabrication process to substantially improve the surface quality achievable in high-resolution...

  13. High resolution cross strip anodes for photon counting detectors

    Science.gov (United States)

    Siegmund, O. H. W.; Tremsin, A. S.; Vallerga, J. V.; Abiad, R.; Hull, J.

    2003-05-01

    A new photon counting, imaging readout for microchannel plate sensors, the cross strip (XS) anode, has been investigated. Charge centroiding of signals detected on two orthogonal layers of sense strip sets are used to derive photon locations. The XS anode spatial resolution (<3 μm FWHM) exceeds the spatial resolution of most direct charge sensing anodes, and does so at low gain (<2×10 6). The image linearity and fidelity are high enough to resolve and map 7 μm MCP pores, offering new possibilities for astronomical and other applications.

  14. High resolution atomic force microscopy of double-stranded RNA

    Science.gov (United States)

    Ares, Pablo; Fuentes-Perez, Maria Eugenia; Herrero-Galán, Elías; Valpuesta, José M.; Gil, Adriana; Gomez-Herrero, Julio; Moreno-Herrero, Fernando

    2016-06-01

    Double-stranded (ds) RNA mediates the suppression of specific gene expression, it is the genetic material of a number of viruses, and a key activator of the innate immune response against viral infections. The ever increasing list of roles played by dsRNA in the cell and its potential biotechnological applications over the last decade has raised an interest for the characterization of its mechanical properties and structure, and that includes approaches using Atomic Force Microscopy (AFM) and other single-molecule techniques. Recent reports have resolved the structure of dsDNA with AFM at unprecedented resolution. However, an equivalent study with dsRNA is still lacking. Here, we have visualized the double helix of dsRNA under near-physiological conditions and at sufficient resolution to resolve the A-form sub-helical pitch periodicity. We have employed different high-sensitive force-detection methods and obtained images with similar spatial resolution. Therefore, we show here that the limiting factors for high-resolution AFM imaging of soft materials in liquid medium are, rather than the imaging mode, the force between the tip and the sample and the sharpness of the tip apex.Double-stranded (ds) RNA mediates the suppression of specific gene expression, it is the genetic material of a number of viruses, and a key activator of the innate immune response against viral infections. The ever increasing list of roles played by dsRNA in the cell and its potential biotechnological applications over the last decade has raised an interest for the characterization of its mechanical properties and structure, and that includes approaches using Atomic Force Microscopy (AFM) and other single-molecule techniques. Recent reports have resolved the structure of dsDNA with AFM at unprecedented resolution. However, an equivalent study with dsRNA is still lacking. Here, we have visualized the double helix of dsRNA under near-physiological conditions and at sufficient resolution to

  15. Design for a focusing high-resolution neutron crystal diffractometer

    CERN Document Server

    Ionita, I; Popovici, M; Popa, N C

    1999-01-01

    A new concept of high-resolution focusing configuration begins to be accepted as an alternative solution to the existing conventional configurations. Among the earliest work performed in this direction is that performed at the Institute for Nuclear Research, Pitesti. These results are presented below. The experimentally determined resolution properties for two focusing configurations obtained at TRIGA reactor Pitesti and at VVRS reactor Bucharest are given in order to be compared with those obtained for the conventional ones. The principles to get focusing in crystal neutron diffractometry are presented. The main characteristics for a focusing instrument are given. (author)

  16. High resolution full-spectrum water Raman lidar

    Institute of Scientific and Technical Information of China (English)

    LIU FuChao; YI Fan; JIA JingYu; ZHANG YunPeng; ZHANG ShaoDong; YU ChangMing; TAN Ying

    2012-01-01

    Knowledge of the temporal-spatial distribution of water content in atmosphere and water phase change in cloud is important for atmospheric study.For this purpose,we have developed a high resolution full-spectrum water Raman lidar that can collect Raman signals from ice,water droplets and water vapor simultaneously.A double-grating polychromator and a 32-channel photomultiplier-tube detector are used to obtain a spectral resolution of ~0.19 nm in the full Raman spectrum range of water.Preliminary observations present the water Raman spectrum characteristics of both the mixed-phase cloud and humid air under cloudless condition.

  17. High resolution polar Kerr magnetometer for nanomagnetism and nanospintronics.

    Science.gov (United States)

    Cormier, M; Ferré, J; Mougin, A; Cromières, J-P; Klein, V

    2008-03-01

    A new high resolution polar magneto-optical (MO) Kerr magnetometer, devoted to the study of nanometer sized elements with perpendicular magnetic anisotropy, is described. The unique performances of this setup in terms of sensitivity (1.2x10(-15) emu), stability (lateral drift +/-35 nm over 3 h), and resolution (laser spot full width at half maximum down to 470 nm) are demonstrated, and illustrated by Kerr hysteresis loop measurements on a unique ultrathin magnetic nanodot, and over small segments of ultranarrow magnetic tracks. Large scanning MO Kerr microscopy images were also obtained with the same performances.

  18. Spatial resolution effects on the assessment of evapotranspiration in olive orchards using high resolution thermal imagery

    Science.gov (United States)

    Santos, Cristina; Zarco-Tejada, Pablo J.; Lorite, Ignacio J.; Allen, Richard G.

    2013-04-01

    The use of remote sensing techniques for estimating surface energy balance and water consumption has significantly improved the characterization of the agricultural systems by determining accurate information about crop evapotranspiration and stress, mainly for extensive crops. However the use of these methodologies for woody crops has been low due to the difficulty in the accurate characterization of these crops, mainly caused by a coarse resolution of the imagery provided by the most widely used satellites (such as Landsat 5 and 7). The coarse spatial resolution provided by these satellite sensors aggregates into a single pixel the tree crown, sunlit and shaded soil components. These surfaces can each exhibit huge differences in temperature, albedo and vegetation indexes calculated in the visible, near infrared and short-wave infrared regions. Recent studies have found that the use of energy balance approaches can provide useful results for non-homogeneous crops (Santos et al., 2012) but detailed analysis is required to determine the effect of the spatial resolution and the aggregation of the scene components in these heterogeneous canopies. In this study a comparison between different spatial resolutions has been conducted using images from Landsat 7 (with thermal resolution of 60m) and from an airborne thermal (with resolution of 80 cm) flown over olive orchards at different dates coincident with the Landsat overpass. The high resolution thermal imagery was resampled at different scales to generate images with spatial resolution ranging from 0.8 m up to 120m (thermal resolution for Landsat 5 images). The selection of the study area was made to avoid those areas with missing Landsat 7 data caused by SLC-off gaps. The selected area has a total area of around 2500 ha and is located in Southern Spain, in the province of Malaga. The selected area is mainly cultivated with olive orchards with different crop practices (rainfed, irrigated, high density, young and adult

  19. SAGA GIS based processing of spatial high resolution temperature data

    Energy Technology Data Exchange (ETDEWEB)

    Gerlitz, Lars; Bechtel, Benjamin; Kawohl, Tobias; Boehner, Juergen [Hamburg Univ. (Germany). Inst. of Geography; Zaksek, Klemen [Hamburg Univ. (Germany). Inst. of Geophysics

    2013-07-01

    Many climate change impact studies require surface and near surface temperature data with high spatial and temporal resolution. The resolution of state of the art climate models and remote sensing data is often by far to coarse to represent the meso- and microscale distinctions of temperatures. This is particularly the case for regions with a huge variability of topoclimates, such as mountainous or urban areas. Statistical downscaling techniques are promising methods to refine gridded temperature data with limited spatial resolution, particularly due to their low demand for computer capacity. This paper presents two downscaling approaches - one for climate model output and one for remote sensing data. Both are methodically based on the FOSS-GIS platform SAGA. (orig.)

  20. Overview on high-resolution ocean modeling in JAMSTEC

    Institute of Scientific and Technical Information of China (English)

    Michio Kawamiya

    2014-01-01

    In view of the importance of ocean component for representing climate change,efforts are underway to implement a high-resolution nesting model system in Model for Interdisciplinary Research on Climate (MI-ROC) for the North Pacific using the same ocean model as used in the coupled model MIROC5. By comparing double (10 km for the northwestern Pacific,50 km for the rest of the Pacific) and triple (double nesting plus 2 km resolution near Japan) nesting,it turns out that relative vorticity is drastically enhanced near Japan with 2 km resolution. It is hoped that such an elaborated nesting system will reveal detailed processes for the ocean heat uptake by,e.g.,intermediate water and mode water formation for which the“perturbed region”near Japan is the key region.

  1. Bendable X-ray Optics for High Resolution Imaging

    Science.gov (United States)

    Gubarev, M.; Ramsey, B.; Kilaru, K.; Atkins, C.; Broadway, D.

    2014-01-01

    Current state-of the-art for x-ray optics fabrication calls for either the polishing of massive substrates into high-angular-resolution mirrors or the replication of thin, lower-resolution, mirrors from perfectly figured mandrels. Future X-ray Missions will require a change in this optics fabrication paradigm in order to achieve sub-arcsecond resolution in light-weight optics. One possible approach to this is to start with perfectly flat, light-weight surface, bend it into a perfect cone, form the desired mirror figure by material deposition, and insert the resulting mirror into a telescope structure. Such an approach is currently being investigated at MSFC, and a status report will be presented detailing the results of finite element analyses, bending tests and differential deposition experiments.

  2. Advances toward high spectral resolution quantum X-ray calorimetry

    Science.gov (United States)

    Moseley, S. H.; Kelley, R. L.; Schoelkopf, R. J.; Szymkowiak, A. E.; Mccammon, D.

    1988-01-01

    Thermal detectors for X-ray spectroscopy combining high spectral resolution and quantum efficiency have been developed. These microcalorimeters measure the energy released in the absorption of a single photon by sensing the rise in temperature of a small absorbing structure. The ultimate energy resolution of such a device is limited by the thermodynamic power fluctuations in the thermal link between the calorimeter and isothermal bath and can in principle be made as low as 1 eV. The performance of a real device is degraded due to noise contributions such as excess 1/f noise in the thermistor and incomplete conversion of energy into phonons. The authors report some recent advances in thermometry, X-ray absorption and thermalization, fabrication techniques, and detector optimization in the presence of noise. These improvements have resulted in a device with a spectral resolution of 17 eV FWHM, measured at 6 keV.

  3. High Resolution Absorption Spectroscopy using Externally Dispersed Interferometry

    Energy Technology Data Exchange (ETDEWEB)

    Edelstein, J; Erskine, D J

    2005-07-06

    We describe the use of Externally Dispersed Interferometry (EDI) for high-resolution absorption spectroscopy. By adding a small fixed-delay interferometer to a dispersive spectrograph, a precise fiducial grid in wavelength is created over the entire spectrograph bandwidth. The fiducial grid interacts with narrow spectral features in the input spectrum to create a moire pattern. EDI uses the moire pattern to obtain new information about the spectra that is otherwise unavailable, thereby improving spectrograph performance. We describe the theory and practice of EDI instruments and demonstrate improvements in the spectral resolution of conventional spectrographs by a factor of 2 to 6. The improvement of spectral resolution offered by EDI can benefit space instruments by reducing spectrograph size or increasing instantaneous bandwidth.

  4. On temporal correlations in high-resolution frequency counting

    CERN Document Server

    Dunker, Tim; Rønningen, Ole Petter

    2016-01-01

    We analyze noise properties of time series of frequency data from different counting modes of a Keysight 53230A frequency counter. We use a 10 MHz reference signal from a passive hydrogen maser connected via phase-stable Huber+Suhner Sucoflex 104 cables to the reference and input connectors of the counter. We find that the high resolution gap-free (CONT) frequency counting process imposes long-term correlations in the output data, resulting in a modified Allan deviation that is characteristic of random walk phase noise. Equally important, the CONT mode results in a frequency bias. In contrast, the counter's undocumented raw continuous mode (RCON) yields unbiased frequency stability estimates with white phase noise characteristics, and of a magnitude consistent with the counter's 20 ps single-shot resolution. Furthermore, we demonstrate that a 100-point running average filter in conjunction with the RCON mode yields resolution enhanced frequency estimates with flicker phase noise characteristics. For instance,...

  5. High Resolution Software Defined Radar System for Target Detection

    Directory of Open Access Journals (Sweden)

    S. Costanzo

    2013-01-01

    Full Text Available The Universal Software Radio Peripheral USRP NI2920, a software defined transceiver so far mainly used in Software Defined Radio applications, is adopted in this work to design a high resolution L-Band Software Defined Radar system. The enhanced available bandwidth, due to the Gigabit Ethernet interface, is exploited to obtain a higher slant-range resolution with respect to the existing Software Defined Radar implementations. A specific LabVIEW application, performing radar operations, is discussed, and successful validations are presented to demonstrate the accurate target detection capability of the proposed software radar architecture. In particular, outdoor and indoor test are performed by adopting a metal plate as reference structure located at different distances from the designed radar system, and results obtained from the measured echo are successfully processed to accurately reveal the correct target position, with the predicted slant-range resolution equal to 6 m.

  6. Interaction of fatigue and creep of GH33 under multi-axial stress at high temperature

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Low-cycle fatigue experiments of tension-compression, torsion and tension-torsion with holding time were performed.The interaction law of creep and fatigue under multiaxial stress at high temperature was investigated, and the micro-mechanism ofequilibrium diagrams was analyzed. A united equation of fatigue life under multiaxial stress was proposed.

  7. Photoacoustic lymphatic imaging with high spatial-temporal resolution

    Science.gov (United States)

    Martel, Catherine; Yao, Junjie; Huang, Chih-Hsien; Zou, Jun; Randolph, Gwendalyn J.; Wang, Lihong V.

    2014-11-01

    Despite its critical function in coordinating the egress of inflammatory and immune cells out of tissues and maintaining fluid balance, the causative role of lymphatic network dysfunction in pathological settings is still understudied. Engineered-animal models and better noninvasive high spatial-temporal resolution imaging techniques in both preclinical and clinical studies will help to improve our understanding of different lymphatic-related pathologic disorders. Our aim was to take advantage of our newly optimized noninvasive wide-field fast-scanning photoacoustic (PA) microcopy system to coordinately image the lymphatic vasculature and its flow dynamics, while maintaining high resolution and detection sensitivity. Here, by combining the optical-resolution PA microscopy with a fast-scanning water-immersible microelectromechanical system scanning mirror, we have imaged the lymph dynamics over a large field-of-view, with high spatial resolution and advanced detection sensitivity. Depending on the application, lymphatic vessels (LV) were spectrally or temporally differentiated from blood vessels. Validation experiments were performed on phantoms and in vivo to identify the LV. Lymphatic flow dynamics in nonpathological and pathological conditions were also visualized. These results indicate that our newly developed PA microscopy is a promising tool for lymphatic-related biological research.

  8. High resolution imaging with impulse based thermoacoustic tomography

    Science.gov (United States)

    Kellnberger, Stephan; Hajiaboli, Amir; Sergiadis, George; Razansky, Daniel; Ntziachristos, Vasilis

    2011-07-01

    Existing imaging modalities like microwave- or radiofrequency (RF) induced thermoacoustic tomography systems show the potential for resolving structures deep inside tissue due to the high penetration properties of RF. However, one of the major drawbacks of existing thermoacoustic tomography systems with pulse modulated carrier frequency excitation is the compromise between efficient signal generation and attainable spatial resolution. In order to overcome limitations of conventional thermoacoustic imaging methods, we herein present and experimentally validate our novel approach towards high resolution thermoacoustic tomography. Instead of carrier-frequency amplification, we utilize ultrahigh-energy electromagnetic impulses at nanosecond duration with near-field energy coupling, thus maintaining thermoacoustic signal strength without compromising spatial resolution. Preliminary experiments on highly absorbing objects, consisting of copper wires with characteristic sizes of ~100 μm, reveal the resolution performance which yields 160 μm. Furthermore, benefits like its cost effectiveness, simplicity and compactness with the potential application in small animal imaging as well as human body imaging show that thermoacoustic tomography with impulse excitation is a promising imaging modality which has a broad range of applications.

  9. High-resolution Imaging Techniques for the Assessment of Osteoporosis

    Science.gov (United States)

    Krug, Roland; Burghardt, Andrew J.; Majumdar, Sharmila; Link, Thomas M.

    2010-01-01

    Synopsis The importance of assessing the bone’s microarchitectural make-up in addition to its mineral density in the context of osteoporosis has been emphasized in a number of publications. The high spatial resolution required to resolve the bone’s microstructure in a clinically feasible scan time is challenging. Currently, the best suited modalities meeting these requirements in vivo are high-resolution peripheral quantitative imaging (HR-pQCT) and magnetic resonance imaging (MRI). Whereas HR-pQCT is limited to peripheral skeleton regions like the wrist and ankle, MRI can also image other sites like the proximal femur but usually with lower spatial resolution. In addition Multidetector-CT has been used for high-resolution imaging of trabecular bone structure, however, the radiation dose is a limiting factor. This article provides an overview of the different modalities, technical requirements and recent developments in this emerging field. Details regarding imaging protocols as well as image post-processing methods for bone structure quantification are discussed. PMID:20609895

  10. Paracoccidioidomycosis: high-resolution computed tomography - anatomo-pathological correlation; Paracoccidioidomicose: correlacao da tomografia computadorizada de alta resolucao com a anatomopatologia

    Energy Technology Data Exchange (ETDEWEB)

    Marchiori, Edson; Muniz, Maria Angelica Soares; Santos, Maria Lucia de Oliveira [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Inst. de Radiologia; Moraes, Heleno Pinto de [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Inst. de Patologia; Capone, Domenico [Universidade do Estado, Rio de Janeiro, RJ (Brazil). Inst. de Pneumologia

    2000-12-01

    We reviewed the high-resolution computed tomography scans of 13 patients with paracoccidioidomycosis and correlated the findings with the anatomo-pathological findings of 5 patients. The most frequent findings observed were thickening of the interlobular septa, emphysema, ground glass areas, thickening of bronchial walls, tracheal dilatation, nodules, cavities and evidence of fibrosing disease such as architectural distortion, parenchymatous bands, spicular pleural thickening, intralobular reticulate and thickening with distortion off the axial interstitium. (author)

  11. Validation of AIRS high-resolution stratospheric temperature retrievals

    Science.gov (United States)

    Meyer, Catrin I.; Hoffmann, Lars

    2014-10-01

    This paper focuses on stratospheric temperature observations by the Atmospheric InfraRed Sounder (AIRS) aboard NASA's Aqua satellite. We validate a nine-year record (2003 - 2011) of data retrieved with a scientific retrieval processor independent from the operational processor operated by NASA. The retrieval discussed here provides stratospheric temperature profiles for each individual AIRS footprint and has nine times better horizontal sampling than the operational data provided by NASA. The high-resolution temperature data are considered optimal for for gravity wave studies. For validation the high-resolution retrieval data are compared with results from the AIRS operational Level-2 data and the ERA-Interim meteorological reanalysis. Due to the large amount of data we performed statistical comparisons of monthly zonal mean cross-sections and time series. The comparisons show that the high-resolution temperature data are in good agreement with the validation data sets. The bias in the zonal averages is mostly within ±2K. The bias reaches a maximum of 7K to ERA-Interim and 4K to the AIRS operational data at the stratopause, it is related to the different resolutions of the data sets. Variability is nearly the same in all three data sets, having maximum standard deviations around the polar vortex in the mid and upper stratosphere. The validation presented here indicates that the high-resolution temperature retrievals are well-suited for scientific studies. In particular, we expect that they will become a valuable asset for future studies of stratospheric gravity waves.

  12. The Conceptual Design of High Pressure Reversible Axial Tunnel Ventilation Fans

    Directory of Open Access Journals (Sweden)

    A. G. Sheard

    2012-01-01

    Full Text Available Tunnel ventilation fans, classically, must have the ability to both supply and extract air from a tunnel system, with the operator's choice dependent on the tunnel ventilation system's operating mode most appropriate at any given point in time. Consequently, tunnel ventilation fans must incorporate a reversible aerodynamic design which limits the maximum fan pressure rise. This paper presents three high pressure reversible fan concepts. These comprise a two-stage counter rotating fan, a single-stage high speed fan, and a two-stage fan with a single motor and impeller on each end of the motor shaft. The authors consider the relative merits of each concept. The third concept offers the most compact fan, transform, silencer, and damper package size. The authors discuss the mechanical design challenges that occur with a two-stage fan with a single motor and impeller on each end of the motor shaft. They present and consider a selected motor bearing arrangement and casing design for maintainability. Finally, the authors present both prototype fan and full-scale package aerodynamic and acoustic performance, before discussing the challenges presented by high temperature certification in accordance with the requirements of EN 12101-3: 2012.

  13. Research on Axial Trail of High-Speed Gas Painting Automizor

    Institute of Scientific and Technical Information of China (English)

    杨志永; 张大卫; 黄田

    2003-01-01

    The non-linear dynamic model is set up of one type of high-speed painting automizor with gas supporting system. The stability of motion and dynamic response of the gas painting automizor system are studied over a relatively wide range of rotating speed by numerical analytic method, the critical velocity under working condition is found, and rotate stability and critical condition are discussed in theory. Furthermore, the range of the critical parameter of the system when Hopf bifurcation occurs and the law between axis trace and bearing clearance are acquired, too.

  14. The Gaia FGK Benchmark Stars - High resolution spectral library

    CERN Document Server

    Blanco-Cuaresma, S; Jofré, P; Heiter, U

    2014-01-01

    Context. An increasing number of high resolution stellar spectra is available today thanks to many past and ongoing spectroscopic surveys. Consequently, numerous methods have been developed in order to perform an automatic spectral analysis on a massive amount of data. When reviewing published results, biases arise and they need to be addressed and minimized. Aims. We are providing a homogeneous library with a common set of calibration stars (known as the Gaia FGK Benchmark Stars) that will allow to assess stellar analysis methods and calibrate spectroscopic surveys. Methods. High resolution and signal-to-noise spectra were compiled from different instruments. We developed an automatic process in order to homogenize the observed data and assess the quality of the resulting library. Results. We built a high quality library that will facilitate the assessment of spectral analyses and the calibration of present and future spectroscopic surveys. The automation of the process minimizes the human subjectivity and e...

  15. Design of UAV high resolution image transmission system

    Science.gov (United States)

    Gao, Qiang; Ji, Ming; Pang, Lan; Jiang, Wen-tao; Fan, Pengcheng; Zhang, Xingcheng

    2017-02-01

    In order to solve the problem of the bandwidth limitation of the image transmission system on UAV, a scheme with image compression technology for mini UAV is proposed, based on the requirements of High-definition image transmission system of UAV. The video codec standard H.264 coding module and key technology was analyzed and studied for UAV area video communication. Based on the research of high-resolution image encoding and decoding technique and wireless transmit method, The high-resolution image transmission system was designed on architecture of Android and video codec chip; the constructed system was confirmed by experimentation in laboratory, the bit-rate could be controlled easily, QoS is stable, the low latency could meets most applied requirement not only for military use but also for industrial applications.

  16. Automated data processing of high-resolution mass spectra

    DEFF Research Database (Denmark)

    Hansen, Michael Adsetts Edberg; Smedsgaard, Jørn

    There has been an almost explosive growth in performance and applications of Electrospray Ionization (ESI) Time of Flight (TOF) mass spectrometry, which today is one of the most efficient tools for screening of metabolites in complex bio-samples. Most efficiently ESI-MS can be used by directly...... infusion of crude extracts into the source taking advantage of the high sensitivity, high mass resolution and accuracy and the limited fragmentation. Unfortunately, there has not been a comparable development in the data processing techniques to fully exploit gain in high resolution and accuracy...... and mass axis on to a fixed one-dimensional array, we obtain a vector that can be used directly as input in multivariate statistics or library search methods. We demonstrate that both cluster- and discriminant analysis as well as PCA (and related methods) can be applied directly on mass spectra from direct...

  17. High Resolution Optical Spectra of HBC 722 after Outburst

    CERN Document Server

    Lee, Jeong-Eun; Lee, Sang-Gak; Sung, Hyun-Il; Lee, Byeong-Cheol; Sung, Hwankyung; Green, Joel D; Jeon, Young-Beom

    2011-01-01

    We report the results of our high resolution optical spectroscopic monitoring campaign ($\\lambda$ = 3800 -- 8800 A, R = 30000 -- 45000) of the new FU Orionis-type object HBC 722. We observed HBC 722 with the BOES 1.8-m telescope between 2010 November 26 and 2010 December 29 and FU Orionis itself on 2011 January 26. We detect a number of previously unreported high-resolution K I and Ca II lines beyond 7500 A. We resolve the H$\\alpha$ and Ca II line profiles into three velocity components, which we attribute to both disk and outflow. The increased accretion during outburst can heat the disk to produce the relatively narrow absorption feature and launch outflows appearing as high velocity blue and redshifted broad features.

  18. Application Research on High Resolution Radar Target Aggregation

    Directory of Open Access Journals (Sweden)

    Zhongzhi Li

    2010-11-01

    Full Text Available In high resolution radar system, the same target always has original data; so we need to merge multiple data from the same target as one target. Because of the system’s real-time requirement, we usually have to carry out target aggregation as quickly as possible. In this paper, we propose a quick target aggregation method based on clustering algorithm. The proposed method divides original data into subsets by single dimensional distance, and then merges subsets according to single dimensional distance and setdensity. At last we apply the proposed method to carry out target aggregation for airport scene surveillance radar system. Experimental result shows the proposed method has high execution efficiency and is not sensitive to noise data; it is useful for high resolution radar target aggregation.

  19. High Resolution X-ray-Induced Acoustic Tomography

    Science.gov (United States)

    Xiang, Liangzhong; Tang, Shanshan; Ahmad, Moiz; Xing, Lei

    2016-05-01

    Absorption based CT imaging has been an invaluable tool in medical diagnosis, biology, and materials science. However, CT requires a large set of projection data and high radiation dose to achieve superior image quality. In this letter, we report a new imaging modality, X-ray Induced Acoustic Tomography (XACT), which takes advantages of high sensitivity to X-ray absorption and high ultrasonic resolution in a single modality. A single projection X-ray exposure is sufficient to generate acoustic signals in 3D space because the X-ray generated acoustic waves are of a spherical nature and propagate in all directions from their point of generation. We demonstrate the successful reconstruction of gold fiducial markers with a spatial resolution of about 350 μm. XACT reveals a new imaging mechanism and provides uncharted opportunities for structural determination with X-ray.

  20. The high Reynolds number flow through an axial-flow pump

    Science.gov (United States)

    Zierke, W. C.; Straka, W. A.; Taylor, P. D.

    1993-11-01

    The high Reynolds number pump (HIREP) facility at ARL Penn State has been used to perform a low-speed, large-scale experiment of the incompressible flow of water through a two-blade-row turbomachine. HIREP can involve blade chord Reynolds numbers as high as 6,000,000 and can accommodate a variety of instrumentation in both a stationary and a rotating frame of reference. The objectives of this experiment were as follows: to provide a database for comparison with three-dimensional, viscous (turbulent) flow computations; to evaluate the engineering models; and to improve our physical understanding of many of the phenomena involved in this complex flow field. The experimental results include a large quantity of data acquired throughout HIREP. A five-hole probe survey of the inlet flow 37.0 percent chord upstream of the inlet guide vane (IGV) leading edge is sufficient to give information for the inflow boundary conditions, while some static-pressure information is available to help establish an outflow boundary condition.

  1. Structural integrity assessments of high pressure pipelines with axial flaws using a micromechanics model

    Energy Technology Data Exchange (ETDEWEB)

    Dotta, Fernando; Ruggieri, Claudio

    2004-09-01

    This study extends a micromechanics approach based upon the computational cell methodology to model ductile crack extension of longitudinal crack-like defects in a high strength pipeline steel. Laboratory testing of an API 5L X60 steel at room temperature using standard, deep crack C(T) specimens provides the data needed to measure the crack growth resistance curve for the material. A simple scheme to calibrate material-specific parameters for the cells employs this measured R-curve. A central focus of the paper is the application of the cell methodology to predict experimentally measured burst pressures for longitudinally pre-cracked pipe specimens. The experimental program includes large-diameter pipe specimens with different crack depth (a) and crack size (2c). Plane-strain computations are conducted on detailed finite element models for the pipe specimens to describe crack extension with increased pressure. The cell model predictions of crack growth response and burst pressure predictions are in good agreement with experimental measurements for the tested pipes. The present methodology holds significant promise as an engineering tool to simulate ductile crack growth and to predict the burst pressure of high pressure pipelines containing crack-like defects.

  2. Experimental Investigation of the Hysteretic Behavior of Wide-Flange Steel Columns under High Axial Load and Lateral Drift Demands

    OpenAIRE

    Lignos, Dimitrios; Cravero, Julien; Elkady, Ahmed Mohamed Ahmed

    2016-01-01

    This paper discusses the findings from a large-scale experimental program that characterized the hysteretic behavior of typical steel wide-flange columns in steel moment-resisting frames (MRFs). The test specimens were tested in a cantilever configuration with a fixed point of inflection. The main testing parameters included various lateral and axial loading histories, the applied axial compressive load and the local slenderness of the cross-section. It is shown that (a) steel columns subject...

  3. Imaging collagen type I fibrillogenesis with high spatiotemporal resolution.

    Science.gov (United States)

    Stamov, Dimitar R; Stock, Erik; Franz, Clemens M; Jähnke, Torsten; Haschke, Heiko

    2015-02-01

    Fibrillar collagens, such as collagen type I, belong to the most abundant extracellular matrix proteins and they have received much attention over the last five decades due to their large interactome, complex hierarchical structure and high mechanical stability. Nevertheless, the collagen self-assembly process is still incompletely understood. Determining the real-time kinetics of collagen type I formation is therefore pivotal for better understanding of collagen type I structure and function, but visualising the dynamic self-assembly process of collagen I on the molecular scale requires imaging techniques offering high spatiotemporal resolution. Fast and high-speed scanning atomic force microscopes (AFM) provide the means to study such processes on the timescale of seconds under near-physiological conditions. In this study we have applied fast AFM tip scanning to study the assembly kinetics of fibrillar collagen type I nanomatrices with a temporal resolution reaching eight seconds for a frame size of 500 nm. By modifying the buffer composition and pH value, the kinetics of collagen fibrillogenesis can be adjusted for optimal analysis by fast AFM scanning. We furthermore show that amplitude-modulation imaging can be successfully applied to extract additional structural information from collagen samples even at high scan rates. Fast AFM scanning with controlled amplitude modulation therefore provides a versatile platform for studying dynamic collagen self-assembly processes at high resolution. Copyright © 2014 Elsevier B.V. All rights reserved.

  4. High-resolution ionization detector and array of such detectors

    Energy Technology Data Exchange (ETDEWEB)

    McGregor, Douglas S. (Ypsilanti, MI); Rojeski, Ronald A. (Pleasanton, CA)

    2001-01-16

    A high-resolution ionization detector and an array of such detectors are described which utilize a reference pattern of conductive or semiconductive material to form interaction, pervious and measurement regions in an ionization substrate of, for example, CdZnTe material. The ionization detector is a room temperature semiconductor radiation detector. Various geometries of such a detector and an array of such detectors produce room temperature operated gamma ray spectrometers with relatively high resolution. For example, a 1 cm.sup.3 detector is capable of measuring .sup.137 Cs 662 keV gamma rays with room temperature energy resolution approaching 2% at FWHM. Two major types of such detectors include a parallel strip semiconductor Frisch grid detector and the geometrically weighted trapezoid prism semiconductor Frisch grid detector. The geometrically weighted detector records room temperature (24.degree. C.) energy resolutions of 2.68% FWHM for .sup.137 Cs 662 keV gamma rays and 2.45% FWHM for .sup.60 Co 1.332 MeV gamma rays. The detectors perform well without any electronic pulse rejection, correction or compensation techniques. The devices operate at room temperature with simple commercially available NIM bin electronics and do not require special preamplifiers or cooling stages for good spectroscopic results.

  5. High-resolution electron microscopy of advanced materials

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, T.E.; Kung, H.H.; Sickafus, K.E.; Gray, G.T. III; Field, R.D.; Smith, J.F. [Los Alamos National Lab., NM (United States). Materials Science and Technology Div.

    1997-11-01

    This final report chronicles a three-year, Laboratory Directed Research and Development (LDRD) project at Los Alamos National Laboratory (LANL). The High-Resolution Electron Microscopy Facility has doubled in size and tripled in quality since the beginning of the three-year period. The facility now includes a field-emission scanning electron microscope, a 100 kV field-emission scanning transmission electron microscope (FE-STEM), a 300 kV field-emission high-resolution transmission electron microscope (FE-HRTEM), and a 300 kV analytical transmission electron microscope. A new orientation imaging microscope is being installed. X-ray energy dispersive spectrometers for chemical analysis are available on all four microscopes; parallel electron energy loss spectrometers are operational on the FE-STEM and FE-HRTEM. These systems enable evaluation of local atomic bonding, as well as chemical composition in nanometer-scale regions. The FE-HRTEM has a point-to-point resolution of 1.6 {angstrom}, but the resolution can be pushed to its information limit of 1 {angstrom} by computer reconstruction of a focal series of images. HRTEM has been used to image the atomic structure of defects such as dislocations, grain boundaries, and interfaces in a variety of materials from superconductors and ferroelectrics to structural ceramics and intermetallics.

  6. High-resolution three-dimensional imaging with compress sensing

    Science.gov (United States)

    Wang, Jingyi; Ke, Jun

    2016-10-01

    LIDAR three-dimensional imaging technology have been used in many fields, such as military detection. However, LIDAR require extremely fast data acquisition speed. This makes the manufacture of detector array for LIDAR system is very difficult. To solve this problem, we consider using compress sensing which can greatly decrease the data acquisition and relax the requirement of a detection device. To use the compressive sensing idea, a spatial light modulator will be used to modulate the pulsed light source. Then a photodetector is used to receive the reflected light. A convex optimization problem is solved to reconstruct the 2D depth map of the object. To improve the resolution in transversal direction, we use multiframe image restoration technology. For each 2D piecewise-planar scene, we move the SLM half-pixel each time. Then the position where the modulated light illuminates will changed accordingly. We repeat moving the SLM to four different directions. Then we can get four low-resolution depth maps with different details of the same plane scene. If we use all of the measurements obtained by the subpixel movements, we can reconstruct a high-resolution depth map of the sense. A linear minimum-mean-square error algorithm is used for the reconstruction. By combining compress sensing and multiframe image restoration technology, we reduce the burden on data analyze and improve the efficiency of detection. More importantly, we obtain high-resolution depth maps of a 3D scene.

  7. Accelerated high-resolution photoacoustic tomography via compressed sensing

    Science.gov (United States)

    Arridge, Simon; Beard, Paul; Betcke, Marta; Cox, Ben; Huynh, Nam; Lucka, Felix; Ogunlade, Olumide; Zhang, Edward

    2016-12-01

    Current 3D photoacoustic tomography (PAT) systems offer either high image quality or high frame rates but are not able to deliver high spatial and temporal resolution simultaneously, which limits their ability to image dynamic processes in living tissue (4D PAT). A particular example is the planar Fabry-Pérot (FP) photoacoustic scanner, which yields high-resolution 3D images but takes several minutes to sequentially map the incident photoacoustic field on the 2D sensor plane, point-by-point. However, as the spatio-temporal complexity of many absorbing tissue structures is rather low, the data recorded in such a conventional, regularly sampled fashion is often highly redundant. We demonstrate that combining model-based, variational image reconstruction methods using spatial sparsity constraints with the development of novel PAT acquisition systems capable of sub-sampling the acoustic wave field can dramatically increase the acquisition speed while maintaining a good spatial resolution: first, we describe and model two general spatial sub-sampling schemes. Then, we discuss how to implement them using the FP interferometer and demonstrate the potential of these novel compressed sensing PAT devices through simulated data from a realistic numerical phantom and through measured data from a dynamic experimental phantom as well as from in vivo experiments. Our results show that images with good spatial resolution and contrast can be obtained from highly sub-sampled PAT data if variational image reconstruction techniques that describe the tissues structures with suitable sparsity-constraints are used. In particular, we examine the use of total variation (TV) regularization enhanced by Bregman iterations. These novel reconstruction strategies offer new opportunities to dramatically increase the acquisition speed of photoacoustic scanners that employ point-by-point sequential scanning as well as reducing the channel count of parallelized schemes that use detector arrays.

  8. Imaging collagen type I fibrillogenesis with high spatiotemporal resolution

    Energy Technology Data Exchange (ETDEWEB)

    Stamov, Dimitar R, E-mail: stamov@jpk.com [JPK Instruments AG, Bouchéstrasse 12, 12435 Berlin (Germany); Stock, Erik [JPK Instruments AG, Bouchéstrasse 12, 12435 Berlin (Germany); Franz, Clemens M [DFG-Center for Functional Nanostructures (CFN), Karlsruhe Institute of Technology (KIT), Wolfgang-Gaede-Strasse 1a, 76131 Karlsruhe (Germany); Jähnke, Torsten; Haschke, Heiko [JPK Instruments AG, Bouchéstrasse 12, 12435 Berlin (Germany)

    2015-02-15

    Fibrillar collagens, such as collagen type I, belong to the most abundant extracellular matrix proteins and they have received much attention over the last five decades due to their large interactome, complex hierarchical structure and high mechanical stability. Nevertheless, the collagen self-assembly process is still incompletely understood. Determining the real-time kinetics of collagen type I formation is therefore pivotal for better understanding of collagen type I structure and function, but visualising the dynamic self-assembly process of collagen I on the molecular scale requires imaging techniques offering high spatiotemporal resolution. Fast and high-speed scanning atomic force microscopes (AFM) provide the means to study such processes on the timescale of seconds under near-physiological conditions. In this study we have applied fast AFM tip scanning to study the assembly kinetics of fibrillar collagen type I nanomatrices with a temporal resolution reaching eight seconds for a frame size of 500 nm. By modifying the buffer composition and pH value, the kinetics of collagen fibrillogenesis can be adjusted for optimal analysis by fast AFM scanning. We furthermore show that amplitude-modulation imaging can be successfully applied to extract additional structural information from collagen samples even at high scan rates. Fast AFM scanning with controlled amplitude modulation therefore provides a versatile platform for studying dynamic collagen self-assembly processes at high resolution. - Highlights: • Continuous non-invasive time-lapse investigation of collagen I fibrillogenesis in situ. • Imaging of collagen I self-assembly with high spatiotemporal resolution. • Application of setpoint modulation to study the hierarchical structure of collagen I. • Observing real-time formation of the D-banding pattern in collagen I.

  9. A CFD analysis of blade row interactions within a high-speed axial compressor

    Science.gov (United States)

    Richman, Michael Scott

    Aircraft engine design provides many technical and financial hurdles. In an effort to streamline the design process, save money, and improve reliability and performance, many manufacturers are relying on computational fluid dynamic simulations. An overarching goal of the design process for military aircraft engines is to reduce size and weight while maintaining (or improving) reliability. Designers often turn to the compression system to accomplish this goal. As pressure ratios increase and the number of compression stages decrease, many problems arise, for example stability and high cycle fatigue (HCF) become significant as individual stage loading is increased. CFD simulations have recently been employed to assist in the understanding of the aeroelastic problems. For accurate multistage blade row HCF prediction, it is imperative that advanced three-dimensional blade row unsteady aerodynamic interaction codes be validated with appropriate benchmark data. This research addresses this required validation process for TURBO, an advanced three-dimensional multi-blade row turbomachinery CFD code. The solution/prediction accuracy is characterized, identifying key flow field parameters driving the inlet guide vane (IGV) and stator response to the rotor generated forcing functions. The result is a quantified evaluation of the ability of TURBO to predict not only the fundamental flow field characteristics but the three dimensional blade loading.

  10. Corner Separation Control by Boundary Layer Suction Applied to a Highly Loaded Axial Compressor Cascade

    Directory of Open Access Journals (Sweden)

    Yangwei Liu

    2014-11-01

    Full Text Available Control of corner separation has attracted much interest due to its improvement of performance and energy utilization in turbomachinery. Numerical studies have been performed under both design and off-design flow conditions to investigate the effects of boundary layer suction (BLS on corner separation in a highly loaded compressor cascade. Two new BLS slot configurations are proposed and a total of five suction slot configurations were studied and compared. Averaged static pressure rise, exit loss coefficient, passage blockage and flow turning angle have been given and compared systematically over a range of operation incidence angles. Distributions of significant loss removal, blade loading, exit deviation and total pressure loss at 3 degree and 7 degree incidence have also been studied. Under the same suction mass flows of 0.7% of the inlet mass flows, the pitchwise suction slot on the endwall shows a better optimal performance over the whole operation incidence among single suction slots. By using of the new proposed compound slot configuration with one spanwise slot on the blade suction side and one pitchwise slot on the endwall, the maximum reduction of total pressure loss at 7 degree incidence can be 39.4%.

  11. Efficient methodologies for system matrix modelling in iterative image reconstruction for rotating high-resolution PET

    Energy Technology Data Exchange (ETDEWEB)

    Ortuno, J E; Kontaxakis, G; Rubio, J L; Santos, A [Departamento de Ingenieria Electronica (DIE), Universidad Politecnica de Madrid, Ciudad Universitaria s/n, 28040 Madrid (Spain); Guerra, P [Networking Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid (Spain)], E-mail: juanen@die.upm.es

    2010-04-07

    A fully 3D iterative image reconstruction algorithm has been developed for high-resolution PET cameras composed of pixelated scintillator crystal arrays and rotating planar detectors, based on the ordered subsets approach. The associated system matrix is precalculated with Monte Carlo methods that incorporate physical effects not included in analytical models, such as positron range effects and interaction of the incident gammas with the scintillator material. Custom Monte Carlo methodologies have been developed and optimized for modelling of system matrices for fast iterative image reconstruction adapted to specific scanner geometries, without redundant calculations. According to the methodology proposed here, only one-eighth of the voxels within two central transaxial slices need to be modelled in detail. The rest of the system matrix elements can be obtained with the aid of axial symmetries and redundancies, as well as in-plane symmetries within transaxial slices. Sparse matrix techniques for the non-zero system matrix elements are employed, allowing for fast execution of the image reconstruction process. This 3D image reconstruction scheme has been compared in terms of image quality to a 2D fast implementation of the OSEM algorithm combined with Fourier rebinning approaches. This work confirms the superiority of fully 3D OSEM in terms of spatial resolution, contrast recovery and noise reduction as compared to conventional 2D approaches based on rebinning schemes. At the same time it demonstrates that fully 3D methodologies can be efficiently applied to the image reconstruction problem for high-resolution rotational PET cameras by applying accurate pre-calculated system models and taking advantage of the system's symmetries.

  12. Imaging living cells with a combined high-resolution multi-photon-acoustic microscope

    Science.gov (United States)

    Schenkl, Selma; Weiss, Eike; Stark, Martin; Stracke, Frank; Riemann, Iris; Lemor, Robert; König, Karsten

    2007-02-01

    With increasing demand for in-vivo observation of living cells, microscope techniques that do not need staining become more and more important. In this talk we present a combined multi-photon-acoustic microscope with the possibility to measure synchronously properties addressed by ultrasound and two-photon fluorescence. Ultrasound probes the local mechanical properties of a cell, while the high resolution image of the two-photon fluorescence delivers insight in cell morphology and activity. In the acoustic part of the microscope an ultrasound wave, with a frequency of GHz, is focused by an acoustic sapphire lens and detected by a piezo electric transducer assembled to the lens. The achieved lateral resolution is in the range of 1μm. Contrast in the images arises mainly from the local absorption of sound in the cells, related to properties, such as mass density, stiffness and viscose damping. Additionally acoustic microscopy can access the cell shape and the state of the cell membrane as it is a intrinsic volume scanning technique.The optical part bases on the emission of fluorescent biomolecules naturally present in cells (e.g. NAD(P)H, protophorphyrin IX, lipofuscin, melanin). The nonlinear effect of two-photon absorption provides a high lateral and axial resolution without the need of confocal detection. In addition, in the near-IR cell damages are drastically reduced in comparison to direct excitation in the visible or UV. Both methods can be considered as minimal invasive, as they relay on intrinsic contrast mechanisms and dispense with the need of staining. First results on living cells are presented and discussed.

  13. Adaptive optics with pupil tracking for high resolution retinal imaging.

    Science.gov (United States)

    Sahin, Betul; Lamory, Barbara; Levecq, Xavier; Harms, Fabrice; Dainty, Chris

    2012-02-01

    Adaptive optics, when integrated into retinal imaging systems, compensates for rapidly changing ocular aberrations in real time and results in improved high resolution images that reveal the photoreceptor mosaic. Imaging the retina at high resolution has numerous potential medical applications, and yet for the development of commercial products that can be used in the clinic, the complexity and high cost of the present research systems have to be addressed. We present a new method to control the deformable mirror in real time based on pupil tracking measurements which uses the default camera for the alignment of the eye in the retinal imaging system and requires no extra cost or hardware. We also present the first experiments done with a compact adaptive optics flood illumination fundus camera where it was possible to compensate for the higher order aberrations of a moving model eye and in vivo in real time based on pupil tracking measurements, without the real time contribution of a wavefront sensor. As an outcome of this research, we showed that pupil tracking can be effectively used as a low cost and practical adaptive optics tool for high resolution retinal imaging because eye movements constitute an important part of the ocular wavefront dynamics.

  14. High-resolution SIT TV tube for subnanosecond image shuttering

    Science.gov (United States)

    Yates, G. J.; Vine, B. H.; Aeby, I.; Dunbar, D. L.; King, N. S. P.; Jaramillo, S. A.; Thayer, N. N.; Noel, B. W.

    1984-09-01

    A new ultrafast high-resolution image shutter tube with reasonable gain and shuttering efficiency has been designed and tested. The design uses a grid-gated silicon-intensified-target (SIT) image section and a high-speed focus projection and scan (FPS) vidicon read-out section in one envelope to eliminate resolution losses from external coupling. The design features low-gate-interface capacity, a high-conductivity shutter grid, and a segmented low-resistivity photocathode for optimum gating speed. Optical gate widths as short as 400 ps + or - 100 ps for full shuttering of the 25-mm-diam input window with spatial resolution as high as 15 1p/mm have been measured. Some design criteria, most of the electrical and optical performance data for several variations in the basic design, and a comparison (of several key response functions) with similarly tested 18- and 25-mm-diam proximity-focused microchannel-plate (MCP) image intensifier tubes (MCPTs) are included.

  15. High stability integrated Tri-axial fluxgate sensor with suspended technology

    Science.gov (United States)

    Wang, Chen; Teng, Yuntian; Wang, Xiaomei; Fan, Xiaoyong; Wu, Qiong

    2017-04-01

    The relative geomagnetic record of China Geomagnetic Network of China(GNC) has been digitized, network, meanwhile achieving second data acquisition and storage during after 9th five-year and 10th five-year plan upgraded. Currently the relative record in geomagnetic observatories are generally two sets of the same type instrument with parallel observation, which could distinguish the differential between observation instrument failures and environmental interference, and ensure the continuity and integrity of the observation data. Fluxgate magnetometer has become mainstream equipment for relative geomagnetic record because of its low noise, high sensitivity, and fast response. There is a problem about data inconsistency by the same type of instrument in the same station though few years observation data analysis. The researchers have done a lot of experiments and found three main error sources:1. The instrument performances, due to the limitation of manufacturing and assembly process level it is difficult to ensure the orthogonality of the instrument; other performances of scale, zero offset and temperature coefficient; 2. horizontal error, which introduced by the initial installation process due to horizontal adjustment and pillar tilling due to long-term observations; 3.The observation environment, the temperature and humidity, power supply system. The new fluxgate magnetometer uses special nonmagnetic gimbaled (made by beryllium / bronze material) construction for suspension, so the fluxgate sensor is fixed at the suspended platform in order to automatically keep the horizontal level. The advantage of this design is to eliminate horizontal error introduced by the initial installation process due to horizontal adjustment and pillar tilling due to long-term observations. The signal processing circuit board is fixed on the top of the suspended platform with certain distance to ensure the static and dynamic magnetic field produced by circuit board no effect to the

  16. High resolution MAS-NMR in combinatorial chemistry.

    Science.gov (United States)

    Shapiro, M J; Gounarides, J S

    High-resolution magic angle spinning (hr-MAS) NMR is a powerful tool for characterizing organic reactions on solid support. Because magic angle spinning reduces the line-broadening due to dipolar coupling and variations in bulk magnetic susceptibility, line widths approaching those obtained in solution-phase NMR can be obtained. The magic angle spinning method is amenable for use in conjunction with a variety of NMR-pulse sequences, making it possible to perform full-structure determinations and conformational analysis on compounds attached to a polymer support. Diffusion-weighted MAS-NMR methods such as SPEEDY (Spin-Echo-Enhanced Diffusion-Filtered Spectroscopy) can be used to remove unwanted signals from the solvent, residual reactants, and the polymer support from the MAS-NMR spectrum, leaving only those signals arising from the resin-bound product. This review will present the applications of high-resolution magic angle spinning NMR for use in combinatorial chemistry research.

  17. High resolution reservoir geological modelling using outcrop information

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Changmin; Lin Kexiang; Liu Huaibo [Jianghan Petroleum Institute, Hubei (China)] [and others

    1997-08-01

    This is China`s first case study of high resolution reservoir geological modelling using outcrop information. The key of the modelling process is to build a prototype model and using the model as a geological knowledge bank. Outcrop information used in geological modelling including seven aspects: (1) Determining the reservoir framework pattern by sedimentary depositional system and facies analysis; (2) Horizontal correlation based on the lower and higher stand duration of the paleo-lake level; (3) Determining the model`s direction based on the paleocurrent statistics; (4) Estimating the sandbody communication by photomosaic and profiles; (6) Estimating reservoir properties distribution within sandbody by lithofacies analysis; and (7) Building the reservoir model in sandbody scale by architectural element analysis and 3-D sampling. A high resolution reservoir geological model of Youshashan oil field has been built by using this method.

  18. Precision cosmology with time delay lenses: high resolution imaging requirements

    CERN Document Server

    Meng, Xiao-Lei; Agnello, Adriano; Auger, Matthew W; Liao, Kai; Marshall, Philip J

    2015-01-01

    Lens time delays are a powerful probe of cosmology, provided that the gravitational potential of the main deflector can be modeled with sufficient precision. Recent work has shown that this can be achieved by detailed modeling of the host galaxies of lensed quasars, which appear as "Einstein Rings" in high resolution images. We carry out a systematic exploration of the high resolution imaging required to exploit the thousands of lensed quasars that will be discovered by current and upcoming surveys with the next decade. Specifically, we simulate realistic lens systems as imaged by the Hubble Space Telescope (HST), James Webb Space Telescope (JWST), and ground based adaptive optics images taken with Keck or the Thirty Meter Telescope (TMT). We compare the performance of these pointed observations with that of images taken by the Euclid (VIS), Wide-Field Infrared Survey Telescope (WFIRST) and Large Synoptic Survey Telescope (LSST) surveys. We use as our metric the precision with which the slope $\\gamma'$ of the...

  19. HIGH AND LOW RESOLUTION TEXTURED MODELS OF COMPLEX ARCHITECTURAL SURFACES

    Directory of Open Access Journals (Sweden)

    E. K. Stathopoulou

    2012-09-01

    Full Text Available During the recent years it has become obvious that 3D technology, applied mainly with the use of terrestrial laser scanners (TLS is the most suitable technique for the complete geometric documentation of complex objects, whether they are monuments or architectural constructions in general. However, it is rather a challenging task to convert an acquired point cloud into a realistic 3D polygonal model that can simultaneously satisfy high resolution modeling and visualization demands. The aim of the visualization of a simple or complex object is to create a 3D model that best describes the reality within the computer environment. This paper is dedicated especially in the visualization of a complex object's 3D model, through high, as well as low resolution textured models. The object of interest for this study was the Almoina (Romanesque Door of the Cathedral of Valencia in Spain.

  20. Fabricating High-Resolution X-Ray Collimators

    Science.gov (United States)

    Appleby, Michael; Atkinson, James E.; Fraser, Iain; Klinger, Jill

    2008-01-01

    A process and method for fabricating multi-grid, high-resolution rotating modulation collimators for arcsecond and sub-arcsecond x-ray and gamma-ray imaging involves photochemical machining and precision stack lamination. The special fixturing and etching techniques that have been developed are used for the fabrication of multiple high-resolution grids on a single array substrate. This technology has application in solar and astrophysics and in a number of medical imaging applications including mammography, computed tomography (CT), single photon emission computed tomography (SPECT), and gamma cameras used in nuclear medicine. This collimator improvement can also be used in non-destructive testing, hydrodynamic weapons testing, and microbeam radiation therapy.

  1. High-resolution ultrasonographic findings in thyroid nodules

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Sun Seob; Lee, Kwan Seh; Kim, Kun Sang; Park, Soo Soung [College of Medicine, Chung-Ang University, Seoul (Korea, Republic of)

    1985-08-15

    Ultrasonography, it's excellent ability of differentiating cystic from solid lesion and depicting detailed architecture, proved itself useful in the diagnosis of thyroid pathologies. Advanced high resolution equipment made hidden small lesion detected and finer structure clearly seen. They seemed to throw light on the histological diagnosis of thyroid diseases, especially differentiation of benignancy and malignancy. Author reviewed pictures of high-resolution ultrasonography of thyroid disease (24 cases) and correlated them with proven pathological findings. The results were as follows: 1. Multiplicity of lesion favors benignancy (4 cases). 2. Well defined margin favors benignancy (14/17), while ill defined margin favors malignancy (3/4), and lesion of no margin favors thyroiditis (3/3). 3. Surrounding halo favors benignancy (7 cases). 4. Hypoechogenicity were found in most of malignancy and thyroiditis. Cystic components in solid nodule were common findings in benign and malignant lesions. Calcification was not found in malignancy.

  2. Temperature-dependent high resolution absorption cross sections of propane

    Science.gov (United States)

    Beale, Christopher A.; Hargreaves, Robert J.; Bernath, Peter F.

    2016-10-01

    High resolution (0.005 cm-1) absorption cross sections have been measured for pure propane (C3H8). These cross sections cover the 2550-3500 cm-1 region at five temperatures (from 296 to 700 K) and were measured using a Fourier transform spectrometer and a quartz cell heated by a tube furnace. Calibrations were made by comparison to the integrated cross sections of propane from the Pacific Northwest National Laboratory. These are the first high resolution absorption cross sections of propane for the 3 μm region at elevated temperatures. The cross sections provided may be used to monitor propane in combustion environments and in astronomical sources such as the auroral regions of Jupiter, brown dwarfs and exoplanets.

  3. High and Low Resolution Textured Models of Complex Architectural Surfaces

    Science.gov (United States)

    Stathopoulou, E. K.; Valanis, A.; Lerma, J. L.; Georgopoulos, A.

    2011-09-01

    During the recent years it has become obvious that 3D technology, applied mainly with the use of terrestrial laser scanners (TLS) is the most suitable technique for the complete geometric documentation of complex objects, whether they are monuments or architectural constructions in general. However, it is rather a challenging task to convert an acquired point cloud into a realistic 3D polygonal model that can simultaneously satisfy high resolution modeling and visualization demands. The aim of the visualization of a simple or complex object is to create a 3D model that best describes the reality within the computer environment. This paper is dedicated especially in the visualization of a complex object's 3D model, through high, as well as low resolution textured models. The object of interest for this study was the Almoina (Romanesque) Door of the Cathedral of Valencia in Spain.

  4. Spatial Ensemble Postprocessing of Precipitation Forecasts Using High Resolution Analyses

    Science.gov (United States)

    Lang, Moritz N.; Schicker, Irene; Kann, Alexander; Wang, Yong

    2017-04-01

    Ensemble prediction systems are designed to account for errors or uncertainties in the initial and boundary conditions, imperfect parameterizations, etc. However, due to sampling errors and underestimation of the model errors, these ensemble forecasts tend to be underdispersive, and to lack both reliability and sharpness. To overcome such limitations, statistical postprocessing methods are commonly applied to these forecasts. In this study, a full-distributional spatial post-processing method is applied to short-range precipitation forecasts over Austria using Standardized Anomaly Model Output Statistics (SAMOS). Following Stauffer et al. (2016), observation and forecast fields are transformed into standardized anomalies by subtracting a site-specific climatological mean and dividing by the climatological standard deviation. Due to the need of fitting only a single regression model for the whole domain, the SAMOS framework provides a computationally inexpensive method to create operationally calibrated probabilistic forecasts for any arbitrary location or for all grid points in the domain simultaneously. Taking advantage of the INCA system (Integrated Nowcasting through Comprehensive Analysis), high resolution analyses are used for the computation of the observed climatology and for model training. The INCA system operationally combines station measurements and remote sensing data into real-time objective analysis fields at 1 km-horizontal resolution and 1 h-temporal resolution. The precipitation forecast used in this study is obtained from a limited area model ensemble prediction system also operated by ZAMG. The so called ALADIN-LAEF provides, by applying a multi-physics approach, a 17-member forecast at a horizontal resolution of 10.9 km and a temporal resolution of 1 hour. The performed SAMOS approach statistically combines the in-house developed high resolution analysis and ensemble prediction system. The station-based validation of 6 hour precipitation sums

  5. High Resolution Aircraft Scanner Mapping of Geothermal and Volcanic Areas

    Energy Technology Data Exchange (ETDEWEB)

    Mongillo, M.A.; Cochrane, G.R.; Wood, C.P.; Shibata, Y.

    1995-01-01

    High spectral resolution GEOSCAN Mkll multispectral aircraft scanner imagery has been acquired, at 3-6 m spatial resolutions, over much of the Taupo Volcanic Zone as part of continuing investigations aimed at developing remote sensing techniques for exploring and mapping geothermal and volcanic areas. This study examined the 24-band: visible, near-IR (NIR), mid-IR (MIR) and thermal-IR (TIR) imagery acquired over Waiotapu geothermal area (3 m spatial resolution) and White Island volcano (6 m resolution). Results show that color composite images composed of visible and NIR wavelengths that correspond to color infrared (CIR) photographic wavelengths can be useful for distinguishing among bare ground, water and vegetation features and, in certain cases, for mapping various vegetation types. However, combinations which include an MIR band ({approx} 2.2 {micro}m) with either visible and NIR bands, or two NIR bands, are the most powerful for mapping vegetation types, water bodies, and bare and hydrothermally altered ground. Combinations incorporating a daytime TIR band with NIR and MIR bands are also valuable for locating anomalously hot features and distinguishing among different types of surface hydrothermal alteration.

  6. A high resolution cavity BPM for the CLIC Test Facility

    Energy Technology Data Exchange (ETDEWEB)

    Chritin, N.; Schmickler, H.; Soby, L.; /CERN; Lunin, A.; Solyak, N.; Wendt, M.; Yakovlev, V.; /Fermilab

    2010-08-01

    In frame of the development of a high resolution BPM system for the CLIC Main Linac we present the design of a cavity BPM prototype. It consists of a waveguide loaded dipole mode resonator and a monopole mode reference cavity, both operating at 15 GHz, to be compatible with the bunch frequencies at the CLIC Test Facility. Requirements, design concept, numerical analysis, and practical considerations are discussed.

  7. High-Resolution Wind Measurements for Offshore Wind Energy Development

    Science.gov (United States)

    Nghiem, Son V.; Neumann, Gregory

    2011-01-01

    A mathematical transform, called the Rosette Transform, together with a new method, called the Dense Sampling Method, have been developed. The Rosette Transform is invented to apply to both the mean part and the fluctuating part of a targeted radar signature using the Dense Sampling Method to construct the data in a high-resolution grid at 1-km posting for wind measurements over water surfaces such as oceans or lakes.

  8. High resolution solar soft X-ray spectrometer

    Institute of Scientific and Technical Information of China (English)

    ZHANG Fei; WANG Huan-Yu; PENG Wen-Xi; LIANG Xiao-Hua; ZHANG Chun-Lei; CAO Xue-Lei; JIANG Wei-Chun; ZHANG Jia-Yu; CUI Xing-Zhu

    2012-01-01

    A high resolution solar soft X-ray spectrometer (SOX) payload onboard a satellite is developed.A silicon drift detector (SDD) is adopted as the detector of the SOX spectrometer.The spectrometer consists of the detectors and their readout electronics,a data acquisition unit and a payload data handling unit.A ground test system is also developed to test SOX.The test results show that the design goals of the spectrometer system have been achieved.

  9. High resolution bathymetry of China seas and their surroundings

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Based on the oceanic lithospheric flexure and the worldwide bathymetric data ETOPO5, the high resolu tion bathymetry of the China seas and their surroundings is computed from altimeter derived gravity anomalies. The new bathymetry obtained by this study is higher resolution and accuracy than the widely used ETOPO5 data, mean while it shows clearly the seafioor, the tectonic characteristics and the geodynamical processes in the China seas.

  10. High-resolution x-ray photoemission spectra of silver

    DEFF Research Database (Denmark)

    Barrie, A.; Christensen, N. E.

    1976-01-01

    An electron spectrometer fitted with an x-ray monochromator for Al Kα1,2 radiation (1486.6 eV) has been used to record high-resolution x-ray photoelectron spectra for the 4d valence band as well as the 3d spin doublet in silver. The core-level spectrum has a line shape that can be described...

  11. High resolution inelastic electron scattering and nuclear structure

    Science.gov (United States)

    Blok, H. B.; Heisenberg, J. H.

    Thanks to the improved characteristics of the experimental set-up electron scattering has become an excellent tool to study the structure of the nucleus. After describing globally how the nuclear structure enters in the formalism of (e,e') reactions and how the high experimental resolution is obtained, several examples of the use of electron scattering for the study of specific nuclear structure questions are discussed.

  12. Tuberculous otitis media: findings on high-resolution CT

    Energy Technology Data Exchange (ETDEWEB)

    Lungenschmid, D. [Dept. of Radiodiagnostics, University Hospital Innsbruck (Austria)]|[Dept. of Magnetic Resonance and Spectroscopy, University Hospital of Innsbruck (Austria); Buchberger, W. [Dept. of Radiodiagnostics, University Hospital Innsbruck (Austria)]|[Dept. of Magnetic Resonance and Spectroscopy, University Hospital of Innsbruck (Austria); Schoen, G. [Dept. of Radiodiagnostics, University Hospital Innsbruck (Austria); Schoepf, R. [Radiologic Inst., Landeck (Austria); Mihatsch, T. [Dept. of Oto-Rhino-Laryngology, University Hospital of Innsbruck (Austria); Birbamer, G. [Dept. of Magnetic Resonance and Spectroscopy, University Hospital of Innsbruck (Austria); Wicke, K. [Inst. of Computed Tomography, University Hospital of Innsbruck (Austria)

    1993-12-01

    We describe two cases of tuberculous otitis media studied with high-resolution computed tomography (CT). Findings included extensive soft tissue densities with fluid levels in the tympanic cavity, the antrum, the mastoid and petrous air cells. Multifocal bony erosions and reactive bone sclerosis were seen as well. CT proved valuable for planning therapy by accurately displaying the involvement of the various structures of the middle and inner ear. However, the specific nature of the disease could only be presumed. (orig.)

  13. Fusion Experiments of HSI and High Resolution Panchromatic Imagery

    Science.gov (United States)

    2007-11-02

    map derived from the unsharpened HSI. The classification is performed with an unsupervised feature extraction using principal component analysis (PCA... Classification of Hyperspectral Data in Urban Area", P. 169-172, SPIE Vol.3502 8. R. C. Gonzalez, P. Wintz, Digital Image Processing, Addison-Wesley...MA 02420-9185 Abstract In this paper, the fusion of hyperspectral imaging (HSI) sensor data and high-resolution panchromatic imagery (HPI) is

  14. Optical alignment of high resolution Fourier transform spectrometers

    Science.gov (United States)

    Breckinridge, J. B.; Ocallaghan, F. G.; Cassie, A. G.

    1980-01-01

    Remote sensing, high resolution FTS instruments often contain three primary optical subsystems: Fore-Optics, Interferometer Optics, and Post, or Detector Optics. We discuss the alignment of a double-pass FTS containing a cat's-eye retro-reflector. Also, the alignment of fore-optics containing confocal paraboloids with a reflecting field stop which relays a field image onto a camera is discussed.

  15. A high resolution cavity BPM for the CLIC Test Facility

    CERN Document Server

    Chritin, N; Soby, L; Lunin, A; Solyak, N; Wendt, M; Yakovlev, V

    2012-01-01

    In frame of the development of a high resolution BPM system for the CLIC Main Linac we present the design of a cavity BPM prototype. It consists of a waveguide loaded dipole mode resonator and a monopole mode reference cavity, both operating at 15 GHz, to be compatible with the bunch frequencies at the CLIC Test Facility. Requirements, design concept, numerical analysis, and practical considerations are discussed.

  16. Chronic pneumonitis of infancy: high-resolution CT findings

    Energy Technology Data Exchange (ETDEWEB)

    Olsen, Oeystein E.; Owens, Catherine M. [Radiology Department, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, WC1N 3JH, London (United Kingdom); Sebire, Neil J. [Histopathology Department, Great Ormond Street Hospital for Children NHS Trust, London (United Kingdom); Jaffe, Adam [Portex Respiratory Medicine Unit, The Institute of Child Health, University College London, London (United Kingdom)

    2004-01-01

    Chronic pneumonitis of infancy (CPI) is a very rare entity. We report the chest radiography and high-resolution CT (HRCT) findings in an infant with histopathologically confirmed CPI. The child was admitted for intensive care 18 h after birth and died at 39 days of age. On HRCT there was diffuse ground-glass change, interlobular septal thickening and discrete centrilobular nodules. An accurate diagnosis is crucial for correct management; however, several entities with the same HRCT findings are recognized. (orig.)

  17. High-resolution CT of lesions of the optic nerve

    Energy Technology Data Exchange (ETDEWEB)

    Peyster, R.G.; Hoover, E.D.; Hershey, B.L.; Haskin, M.E.

    1983-05-01

    The optic nerves are well demonstrated by high-resolution computed tomography. Involvement of the optic nerve by optic gliomas and optic nerve sheath meningiomas is well known. However, nonneoplastic processes such as increased intracranial pressure, optic neuritis, Grave ophthalmopathy, and orbital pseudotumor may also alter the appearance of the optic nerve/sheath on computed tomography. Certain clinical and computed tomographic features permit distinction of these nonneoplastic tumefactions from tumors.

  18. Yeast expression proteomics by high-resolution mass spectrometry

    DEFF Research Database (Denmark)

    Walther, Tobias C; Olsen, Jesper Velgaard; Mann, Matthias

    2010-01-01

    -translational controls contribute majorly to regulation of protein abundance, for example in heat shock stress response. The development of new sample preparation methods, high-resolution mass spectrometry and novel bioinfomatic tools close this gap and allow the global quantitation of the yeast proteome under different...... conditions. Here, we provide background information on proteomics by mass-spectrometry and describe the practice of a comprehensive yeast proteome analysis....

  19. Progress Toward A Very High Angular Resolution Imaging Spectrometer (VERIS)

    Science.gov (United States)

    Korendyke, Clarence M.; Vourlidas, A.; Landi, E.; Seely, J.; Klimchuck, J.

    2007-07-01

    Recent imaging at arcsecond (TRACE) and sub-arcsecond (VAULT) spatial resolution clearly show that structures with fine spatial scales play a key role in the physics of the upper solar atmosphere. Both theoretical and observational considerations point to the importance of small spatial scales, impulsive energy release, strong dynamics, and extreme plasma nonuniformity. Fundamental questions regarding the nature, structure, properties and dynamics of loops and filamentary structures in the upper atmosphere have been raised. To address these questions, we are developing a next generation, VEry high angular Resolution Imaging Spectrometer (VERIS) as a sounding rocket instrument. VERIS will obtain the necessary high spatial resolution, high fidelity measurements of plasma temperatures, densities and velocities. With broad simultaneous temperature coverage, the VERIS observations will directly address unresolved issues relating to interconnections of various temperature solar plasmas. VERIS will provide the first ever subarcsecond spectra of transition region and coronal structures. It will do so with a sufficient spectral resolution of to allow centroided Doppler velocity determinations to better than 3 km/s. VERIS uses a novel two element, normal incidence optical design with highly reflective EUV coatings to access a spectral range with broad temperature coverage (0.03-15 MK) and density-sensitive line ratios. Finally, in addition to the spectra, VERIS will simultaneously obtain spectrally pure slot images (10x150 arcsec) in the +/-1 grating orders, which can be combined to make instantaneous line-of-sight velocity maps with 8km/s accuracy over an unprecedented field of view. The VERIS program is beginning the second year of its three year development cycle. All design activities and reviews are complete. Fabrication of all major components has begun. Brassboard electronics cards have been fabricated, assembled and tested. The paper presents the essential scientific

  20. Design of a Tri-PET collimator for high-resolution whole-body mouse imaging.

    Science.gov (United States)

    DiFilippo, Frank P

    2017-08-01

    Tri-PET refers to high-resolution 511-keV emission tomography using a multipinhole collimator in conjunction with lower resolution PET detectors operating in coincidence mode. Tri-PET is unique in that three spatial locations are associated with each event (two detector coordinates and one pinhole location). Spatial resolution and sensitivity are similar to that of 511-keV SPECT and are governed mainly by the collimator design. However because of a third spatial location in Tri-PET, the line-of-response is overdetermined. This feature permits new opportunities in data processing which impact collimator design. In particular, multiplexing can be avoided since the coincidence data identify the pinhole through which the photon passed. In this paper, the principles of Tri-PET collimator design are reviewed and then applied to the case of high-resolution imaging of a small animal in a clinical PET scanner. The design of a 148-pinhole collimator for whole-body imaging of a mouse is presented. Two pinhole designs were investigated: knife-edge pinholes with 1.1 mm aperture and novel hyperboloidal pinholes with 1.2 mm aperture, both having 18° cone angle. The pinhole configuration is unfocused, covering a whole-body mouse field of view with nearly uniform sensitivity. Computer simulations were performed of a micro hot rods phantom imaged with this collimator in a clinical PET scanner. Sensitivity was estimated by simulating a point source centered on-axis at locations spanning a 70-mm axial range, similar to the NEMA NU-4 standard for whole-body mouse imaging. Reconstructed images of the hot rods phantom demonstrated the ability to resolve 1.1 mm structures with the knife-edge pinholes and 1.0 mm structures with the hyperboloidal pinholes. Sensitivity was found to be 0.093% and 0.054% for the knife-edge and hyperboloidal pinholes, respectively. With a properly designed multipinhole collimator, high-resolution and acceptable sensitivity are achievable with Tri-PET using

  1. High Spectral Resolution, High Cadence, Imaging X-ray Microcalorimeters for Solar Physics - Phase 2 Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Microcalorimeter x-ray instruments are non-dispersive, high spectral resolution, broad-band, high cadence imaging spectrometers. We have been developing these...

  2. A high-resolution record of Greenland mass balance

    Science.gov (United States)

    McMillan, Malcolm; Leeson, Amber; Shepherd, Andrew; Briggs, Kate; Armitage, Thomas W. K.; Hogg, Anna; Kuipers Munneke, Peter; Broeke, Michiel; Noël, Brice; Berg, Willem Jan; Ligtenberg, Stefan; Horwath, Martin; Groh, Andreas; Muir, Alan; Gilbert, Lin

    2016-07-01

    We map recent Greenland Ice Sheet elevation change at high spatial (5 km) and temporal (monthly) resolution using CryoSat-2 altimetry. After correcting for the impact of changing snowpack properties associated with unprecedented surface melting in 2012, we find good agreement (3 cm/yr bias) with airborne measurements. With the aid of regional climate and firn modeling, we compute high spatial and temporal resolution records of Greenland mass evolution, which correlate (R = 0.96) with monthly satellite gravimetry and reveal glacier dynamic imbalance. During 2011-2014, Greenland mass loss averaged 269 ± 51 Gt/yr. Atmospherically driven losses were widespread, with surface melt variability driving large fluctuations in the annual mass deficit. Terminus regions of five dynamically thinning glaciers, which constitute less than 1% of Greenland's area, contributed more than 12% of the net ice loss. This high-resolution record demonstrates that mass deficits extending over small spatial and temporal scales have made a relatively large contribution to recent ice sheet imbalance.

  3. High resolution ultrasonic spectroscopy system for nondestructive evaluation

    Science.gov (United States)

    Chen, C. H.

    1991-01-01

    With increased demand for high resolution ultrasonic evaluation, computer based systems or work stations become essential. The ultrasonic spectroscopy method of nondestructive evaluation (NDE) was used to develop a high resolution ultrasonic inspection system supported by modern signal processing, pattern recognition, and neural network technologies. The basic system which was completed consists of a 386/20 MHz PC (IBM AT compatible), a pulser/receiver, a digital oscilloscope with serial and parallel communications to the computer, an immersion tank with motor control of X-Y axis movement, and the supporting software package, IUNDE, for interactive ultrasonic evaluation. Although the hardware components are commercially available, the software development is entirely original. By integrating signal processing, pattern recognition, maximum entropy spectral analysis, and artificial neural network functions into the system, many NDE tasks can be performed. The high resolution graphics capability provides visualization of complex NDE problems. The phase 3 efforts involve intensive marketing of the software package and collaborative work with industrial sectors.

  4. Multimodal microscopy with high resolution spectral focusing CARS

    Science.gov (United States)

    Baldacchini, Tommaso; Zadoyan, Ruben

    2014-02-01

    In this work we describe a device that extends capabilities of multiphoton microscopes based on dual wavelength output femtosecond laser sources. CARS with 17cm-1 spectral resolution is experimentally demonstrated. Our approach is based on spectral focusing CARS. For pulse shaping of the pump and Stokes beams we utilize transmission gratings based stretcher. It allows the dispersion of the stretcher to be continuously adjusted in wide range. The best spectral resolution is achieved when the chirp rates in both pump and Stokes beam are matched. The device is automated. Any change in the beam path lengths due to the stretcher adjustment or wavelength tuning is compensated by the delay line. We incorporated into the device a computer controlled beam pointing stabilization system that compensates the beam pointing deviation due to dispersion in the system. High level of automation and computer control makes the operation of the device easy. We present CARS images of several samples that demonstrate high spectral resolution, high contrast and chemical selectivity.

  5. Development of a high resolution module for PET scanners

    Science.gov (United States)

    Stringhini, G.; Pizzichemi, M.; Ghezzi, A.; Stojkovic, A.; Tavernier, S.; Niknejad, T.; Varela, J.; Paganoni, M.; Auffray, E.

    2017-02-01

    Positron Emission Tomography (PET) scanners require high performances in term of spatial resolution and sensitivity to allow early detection of cancer masses. In small animal and organ dedicated PET scanners the Depth of Interaction (DOI) information has to be obtained to avoid parallax errors and to reconstruct high resolution images. In the whole body PET, the DOI information can be useful to correct for the time jitter of the optical photons along the main axis of the scintillator, improving the time performances. In this work we present the development of PET module designed to reach high performance as compared to the current scanners while keeping the complexity of the system reasonably low. The module presented is based on a 64 LYSO (Lutetium-yttrium oxyorthosilicate) crystals matrix and on a 4×4 MPPC (Multi Pixels Photon Counter) array as detector in a 4 to 1 coupling between the crystals and the detector and a single side readout. The lateral surfaces of the crystals are optically treated to be unpolished. The DOI and the energy resolution of the PET module are presented and a fast method to obtain the DOI calibration is discussed.

  6. High resolution, large dynamic range field map estimation

    Science.gov (United States)

    Dagher, Joseph; Reese, Timothy; Bilgin, Ali

    2013-01-01

    Purpose We present a theory and a corresponding method to compute high resolution field maps over a large dynamic range. Theory and Methods We derive a closed-form expression for the error in the field map value when computed from two echoes. We formulate an optimization problem to choose three echo times which result in a pair of maximally distinct error distributions. We use standard field mapping sequences at the prescribed echo times. We then design a corresponding estimation algorithm which takes advantage of the optimized echo times to disambiguate the field offset value. Results We validate our method using high resolution images of a phantom at 7T. The resulting field maps demonstrate robust mapping over both a large dynamic range, and in low SNR regions. We also present high resolution offset maps in vivo using both, GRE and MEGE sequences. Even though the proposed echo time spacings are larger than the well known phase aliasing cutoff, the resulting field maps exhibit a large dynamic range without the use of phase unwrapping or spatial regularization techniques. Conclusion We demonstrate a novel 3-echo field map estimation method which overcomes the traditional noise-dynamic range trade-off. PMID:23401245

  7. High Resolution CO Observations of Massive Star Forming Regions

    CERN Document Server

    Klaassen, P D; Keto, E R; Zhang, Q; Galván-Madrid, R; Liu, H-Y B

    2011-01-01

    Context. To further understand the processes involved in the formation of massive stars, we have undertaken a study of the gas dynamics surrounding three massive star forming regions. By observing the large scale structures at high resolution, we are able to determine properties such as driving source, and spatially resolve the bulk dynamical properties of the gas such as infall and outflow. Aims. With high resolution observations, we are able to determine which of the cores in a cluster forming massive stars is responsible for the large scale structures. Methods. We present CO observations of three massive star forming regions with known HII regions and show how the CO traces both infall and outflow. By combining data taken in two SMA configurations with JCMT observations, we are able to see large scale structures at high resolution. Results. We find large (0.26-0.40 pc), massive (2-3 M_sun) and energetic (13-17 \\times 10^44 erg) outflows emanating from the edges of two HII regions suggesting they are being ...

  8. High resolution, MRI-based, segmented, computerized head phantom

    Energy Technology Data Exchange (ETDEWEB)

    Zubal, I.G.; Harrell, C.R.; Smith, E.O.; Smith, A.L.; Krischlunas, P. [Yale Univ., New Haven, CT (United States). Dept. of Diagnostic Radiology

    1999-01-01

    The authors have created a high-resolution software phantom of the human brain which is applicable to voxel-based radiation transport calculations yielding nuclear medicine simulated images and/or internal dose estimates. A software head phantom was created from 124 transverse MRI images of a healthy normal individual. The transverse T2 slices, recorded in a 256x256 matrix from a GE Signa 2 scanner, have isotropic voxel dimensions of 1.5 mm and were manually segmented by the clinical staff. Each voxel of the phantom contains one of 62 index numbers designating anatomical, neurological, and taxonomical structures. The result is stored as a 256x256x128 byte array. Internal volumes compare favorably to those described in the ICRP Reference Man. The computerized array represents a high resolution model of a typical human brain and serves as a voxel-based anthropomorphic head phantom suitable for computer-based modeling and simulation calculations. It offers an improved realism over previous mathematically described software brain phantoms, and creates a reference standard for comparing results of newly emerging voxel-based computations. Such voxel-based computations lead the way to developing diagnostic and dosimetry calculations which can utilize patient-specific diagnostic images. However, such individualized approaches lack fast, automatic segmentation schemes for routine use; therefore, the high resolution, typical head geometry gives the most realistic patient model currently available.

  9. High-Resolution CH Observations of Two Translucent Molecular Clouds

    Science.gov (United States)

    Chastain, Raymond J.; Cotten, David; Magnani, Loris

    2010-01-01

    We present high-resolution (1farcm3 × 1farcm6) observations of the CH 2Π1/2 (F = 1-1) emission line at 3335 MHz in two high-latitude translucent clouds, MBM 3 and 40. At the assumed cloud distances, the angular resolution corresponds to ~0.05 pc, nearly an order of magnitude better than previous studies. Comparisons of the CH emission with previously obtained CO(1-0) data are difficult to interpret: the CO and CH line emission correlates in MBM 40 but not in MBM 3. In both clouds, there is a spatial offset in the peak emission, and perhaps in velocity for MBM 40. The difference in emission characteristics for the two tracers are noticeable in these two nearby clouds because of the high spatial resolution. Since both CH and CO are deemed to be reliable tracers of H2, our results indicate that more care should be taken when using one of these tracers to determine the mass of a nearby molecular cloud.

  10. Definition for Rheumatoid Arthritis Erosions Imaged with High Resolution Peripheral Quantitative Computed Tomography and Interreader Reliability for Detection and Measurement.

    Science.gov (United States)

    Barnabe, Cheryl; Toepfer, Dominique; Marotte, Hubert; Hauge, Ellen-Margrethe; Scharmga, Andrea; Kocijan, Roland; Kraus, Sebastian; Boutroy, Stephanie; Schett, Georg; Keller, Kresten Krarup; de Jong, Joost; Stok, Kathryn S; Finzel, Stephanie

    2016-10-01

    High-resolution peripheral quantitative computed tomography (HR-pQCT) sensitively detects erosions in rheumatoid arthritis (RA); however, nonpathological cortical bone disruptions are potentially misclassified as erosive. Our objectives were to set and test a definition for pathologic cortical bone disruptions in RA and to standardize reference landmarks for measuring erosion size. HR-pQCT images of metacarpophalangeal joints of RA and control subjects were used in an iterative process to achieve consensus on the definition and reference landmarks. Independent readers (n = 11) applied the definition to score 58 joints and measure pathologic erosions in 2 perpendicular multiplanar reformations for their maximum width and depth. Interreader reliability for erosion detection and variability in measurements between readers [root mean square coefficient of variation (RMSCV), intraclass correlation (ICC)] were calculated. Pathologic erosions were defined as cortical breaks extending over a minimum of 2 consecutive slices in perpendicular planes, with underlying trabecular bone loss and a nonlinear shape. Interreader agreement for classifying pathologic erosions was 90.2%, whereas variability for width and depth erosion assessment was observed (RMSCV perpendicular width 12.3%, axial width 20.6%, perpendicular depth 24.0%, axial depth 22.2%; ICC perpendicular width 0.206, axial width 0.665, axial depth 0.871, perpendicular depth 0.783). Mean erosion width was 1.84 mm (range 0.16-8.90) and mean depth was 1.86 mm (range 0.30-8.00). We propose a new definition for erosions visualized with HR-pQCT imaging. Interreader reliability for erosion detection is good, but further refinement of selection of landmarks for erosion size measurement, or automated volumetric methods, will be pursued.

  11. The contribution of high-resolution multiplanar reformats of the skull base to the detection of skull-base fractures

    Energy Technology Data Exchange (ETDEWEB)

    Connor, S.E.J. [Neuroradiology Department, Kings College Hospital, Denmark Hill, London (United Kingdom)]. E-mail: steve.connor@kch.nhs.uk; Flis, C. [Neuroradiology Department, Kings College Hospital, Denmark Hill, London (United Kingdom)

    2005-08-01

    AIM: To investigate the contribution of routine review of submillimetric multiplanar reformats to the diagnosis of skull-base fractures. METHODS: A prospective analysis was performed of 407 cases referred over a 6-month period for CT of the skull following cranial trauma. The reformatted 5-mm axial sections and subsequently the high-resolution multiplanar reformats (HRMPRs) were viewed on an ADW 4.1 workstation using bone windows and algorithm. All skull-base fractures and related features, recorded by the consensus of two radiologists, were classified as anatomically significant or non-significant on the basis of eight criteria. The clinical features of skull-base injury and any subsequent treatment were noted in all cases of skull-base fracture. RESULTS: HRMPRs detected 80 separate skull-base fractures in 36/407 cases. Of these 80 fractures, 57 were visible on 5-mm axial sections. In 8 of the 36 cases, the significant anatomical features were only evident on review of the HRMPRs. In 6 of the 36 cases, none of the skull-base fractures was visible on 5-mm sections, but these individuals had only minor associated clinical features and no therapeutic requirements. Review of HRMPRs could have been confined to patients with skull-base fractures, abnormal intracranial and extracranial air collections or opacified mastoid air cells revealed by 5-mm axial sections. This policy would have led to the detection of 79/80 (99%) of skull-base fractures and all significant anatomical features. CONCLUSION: The 5-mm axial sections demonstrated 71% of skull-base fractures and 78% of skull-base fractures with significant anatomical features, using HRMPRs as a gold standard. There were no significant clinical sequelae at short-term follow-up of those fractures only evident on HRMPRs.

  12. Study of axial magnetic effect

    Energy Technology Data Exchange (ETDEWEB)

    Braguta, Victor [IHEP, Protvino, Moscow region, 142284 Russia ITEP, B. Cheremushkinskaya street 25, Moscow, 117218 (Russian Federation); School of Biomedicine, Far Eastern Federal University, Ajax 10 Building 25, Russian island, Vladivostok, 690922 (Russian Federation); Chernodub, M. N. [CNRS, Laboratoire de Mathématiques et Physique Théorique, Université François-Rabelais Tours, Fédération Denis Poisson, Parc de Grandmont, 37200 Tours, France Department of Physics and Astronomy, University of Gent, Krijgslaan 281, S9, B-9000 Gent (Belgium); School of Biomedicine, Far Eastern Federal University, Ajax 10 Building 25, Russian island, Vladivostok, 690922 (Russian Federation); Goy, V. A. [School of Natural Sciences, Far Eastern Federal University, Sukhanova street 8, Vladivostok, 690950 (Russian Federation); Landsteiner, K. [Instituto de Física Teórica UAM/CSIC, C/ Nicolás Cabrera 13-15, Universidad Autónoma de Madrid, Cantoblanco, 28049 Madrid (Spain); Molochkov, A. V. [School of Biomedicine, Far Eastern Federal University, Ajax 10 Building 25, Russian island, Vladivostok, 690922 (Russian Federation); Ulybyshev, M. [ITEP, B. Cheremushkinskaya street 25, Moscow, 117218 Russia Institute for Theoretical Problems of Microphysics, Moscow State University, Moscow, 119899 (Russian Federation)

    2016-01-22

    The Axial Magnetic Effect manifests itself as an equilibrium energy flow of massless fermions induced by the axial (chiral) magnetic field. Here we study the Axial Magnetic Effect in the quenched SU(2) lattice gauge theory with massless overlap fermions at finite temperature. We numerically observe that in the low-temperature hadron phase the effect is absent due to the quark confinement. In the high-temperature deconfinement phase the energy flow is an increasing function of the temperature which reaches the predicted asymptotic T{sup 2} behavior at high temperatures. We find, however, that energy flow is about one order of magnitude lower compared to a theoretical prediction.

  13. 3-Dimensional modelling of chick embryo eye development and growth using high resolution magnetic resonance imaging.

    Science.gov (United States)

    Goodall, Nicola; Kisiswa, Lilian; Prashar, Ankush; Faulkner, Stuart; Tokarczuk, Paweł; Singh, Krish; Erichsen, Jonathan T; Guggenheim, Jez; Halfter, Willi; Wride, Michael A

    2009-10-01

    Magnetic resonance imaging (MRI) is a powerful tool for generating 3-dimensional structural and functional image data. MRI has already proven valuable in creating atlases of mouse and quail development. Here, we have exploited high resolution MRI to determine the parameters necessary to acquire images of the chick embryo eye. Using a 9.4 Tesla (400 MHz) high field ultra-shielded and refrigerated magnet (Bruker), MRI was carried out on paraformaldehyde-fixed chick embryos or heads at E4, E6, E8, and E10. Image data were processed using established and custom packages (MRICro, ImageJ, ParaVision, Bruker and mri3dX). Voxel dimensions ranged from 62.5 microm to 117.2 microm. We subsequently used the images obtained from the MRI data in order to make precise measurements of chick embryo eye surface area, volume and axial length from E4 to E10. MRI was validated for accurate sizing of ocular tissue features by direct comparison with previously published literature. Furthermore, we demonstrate the utility of high resolution MRI for making accurate measurements of morphological changes due to experimental manipulation of chick eye development, thereby facilitating a better understanding of the effects on chick embryo eye development and growth of such manipulations. Chondroitin sulphate or heparin were microinjected into the vitreous cavity of the right eyes of each of 3 embryos at E5. At E10, embryos were fixed and various eye parameters (volume, surface area, axial length and equatorial diameter) were determined using MRI and normalised with respect to the un-injected left eyes. Statistically significant alterations in eye volume (p < 0.05; increases with chondroitin sulphate and decreases with heparin) and changes in vitreous homogeneity were observed in embryos following microinjection of glycosaminoglycans. Furthermore, in the heparin-injected eyes, significant disturbances at the vitreo-retinal boundary were observed as well as retinal folding and detachment

  14. The Impact of Horizontal and Temporal Resolution on Convection and Precipitation with High-Resolution GEOS-5

    Science.gov (United States)

    Putman, William P.

    2012-01-01

    Using a high-resolution non-hydrostatic version of GEOS-5 with the cubed-sphere finite-volume dynamical core, the impact of spatial and temporal resolution on cloud properties will be evaluated. There are indications from examining convective cluster development in high resolution GEOS-5 forecasts that the temporal resolution within the model may playas significant a role as horizontal resolution. Comparing modeled convective cloud clusters versus satellite observations of brightness temperature, we have found that improved. temporal resolution in GEOS-S accounts for a significant portion of the improvements in the statistical distribution of convective cloud clusters. Using satellite simulators in GEOS-S we will compare the cloud optical properties of GEOS-S at various spatial and temporal resolutions with those observed from MODIS. The potential impact of these results on tropical cyclone formation and intensity will be examined as well.

  15. High resolution modeling of a small urban catchment

    Science.gov (United States)

    Skouri-Plakali, Ilektra; Ichiba, Abdellah; Gires, Auguste; Tchiguirinskaia, Ioulia; Schertzer, Daniel

    2016-04-01

    Flooding is one of the most complex issues that urban environments have to deal with. In France, flooding remains the first natural risk with 72% of decrees state of natural disaster issued between October 1982 and mid-November 2014. Flooding is a result of meteorological extremes that are usually aggravated by the hydrological behavior of urban catchments and human factors. The continuing urbanization process is indeed changing the whole urban water cycle by limiting the infiltration and promoting runoff. Urban environments are very complex systems due to their extreme variability, the interference between human activities and natural processes but also the effect of the ongoing urbanization process that changes the landscape and hardly influences their hydrologic behavior. Moreover, many recent works highlight the need to simulate all urban water processes at their specific temporal and spatial scales. However, considering urban catchments heterogeneity still challenging for urban hydrology, even after advances noticed in term of high-resolution data collection and computational resources. This issue is more to be related to the architecture of urban models being used and how far these models are ready to take into account the extreme variability of urban catchments. In this work, high spatio-temporal resolution modeling is performed for a small and well-equipped urban catchment. The aim of this work is to identify urban modeling needs in terms of spatial and temporal resolution especially for a very small urban area (3.7 ha urban catchment located in the Perreux-sur-Marne city at the southeast of Paris) MultiHydro model was selected to carry out this work, it is a physical based and fully distributed model that interacts four existing modules each of them representing a portion of the water cycle in urban environments. MultiHydro was implemented at 10m, 5m and 2m resolution. Simulations were performed at different spatio-temporal resolutions and analyzed with

  16. Distributed Modeling with Parflow using High Resolution LIDAR Data

    Science.gov (United States)

    Barnes, M.; Welty, C.; Miller, A. J.

    2012-12-01

    Urban landscapes provide a challenging domain for the application of distributed surface-subsurface hydrologic models. Engineered water infrastructure and altered topography influence surface and subsurface flow paths, yet these effects are difficult to quantify. In this work, a parallel, distributed watershed model (ParFlow) is used to simulate urban watersheds using spatial data at the meter and sub-meter scale. An approach using GRASS GIS (Geographic Resources Analysis Support System) is presented that incorporates these data to construct inputs for the ParFlow simulation. LIDAR topography provides the basis for the fully coupled overland flow simulation. Methods to address real discontinuities in the urban land-surface for use with the grid-based kinematic wave approximation used in ParFlow are presented. The spatial distribution of impervious surface is delineated accurately from high-resolution land cover data; hydrogeological properties are specified from literature values. An application is presented for part of the Dead Run subwatershed of the Gwynns Falls in Baltimore County, MD. The domain is approximately 3 square kilometers, and includes a highly impacted urban stream, a major freeway, and heterogeneous urban development represented at a 10-m horizontal resolution and 1-m vertical resolution. This resolution captures urban features such as building footprints and highways at an appropriate scale. The Dead Run domain provides an effective test case for ParFlow application at the fine scale in an urban environment. Preliminary model runs employ a homogeneous subsurface domain with no-flow boundaries. Initial results reflect the highly articulated topography of the road network and the combined influence of surface runoff from impervious surfaces and subsurface flux toward the channel network. Subsequent model runs will include comparisons of the coupled surface-subsurface response of alternative versions of the Dead Run domain with and without impervious

  17. High resolution OCT image generation using super resolution via sparse representation

    Science.gov (United States)

    Asif, Muhammad; Akram, Muhammad Usman; Hassan, Taimur; Shaukat, Arslan; Waqar, Razi

    2017-02-01

    In this paper we propose a technique for obtaining a high resolution (HR) image from a single low resolution (LR) image -using joint learning dictionary - on the basis of image statistic research. It suggests that with an appropriate choice of an over-complete dictionary, image patches can be well represented as a sparse linear combination. Medical imaging for clinical analysis and medical intervention is being used for creating visual representations of the interior of a body, as well as visual representation of the function of some organs or tissues (physiology). A number of medical imaging techniques are in use like MRI, CT scan, X-rays and Optical Coherence Tomography (OCT). OCT is one of the new technologies in medical imaging and one of its uses is in ophthalmology where it is being used for analysis of the choroidal thickness in the eyes in healthy and disease states such as age-related macular degeneration, central serous chorioretinopathy, diabetic retinopathy and inherited retinal dystrophies. We have proposed a technique for enhancing the OCT images which can be used for clearly identifying and analyzing the particular diseases. Our method uses dictionary learning technique for generating a high resolution image from a single input LR image. We train two joint dictionaries, one with OCT images and the second with multiple different natural images, and compare the results with previous SR technique. Proposed method for both dictionaries produces HR images which are comparatively superior in quality with the other proposed method of SR. Proposed technique is very effective for noisy OCT images and produces up-sampled and enhanced OCT images.

  18. High Resolution Continuous Flow Analysis System for Polar Ice Cores

    Science.gov (United States)

    Dallmayr, Remi; Azuma, Kumiko; Yamada, Hironobu; Kjær, Helle Astrid; Vallelonga, Paul; Azuma, Nobuhiko; Takata, Morimasa

    2014-05-01

    In the last decades, Continuous Flow Analysis (CFA) technology for ice core analyses has been developed to reconstruct the past changes of the climate system 1), 2). Compared with traditional analyses of discrete samples, a CFA system offers much faster and higher depth resolution analyses. It also generates a decontaminated sample stream without time-consuming sample processing procedure by using the inner area of an ice-core sample.. The CFA system that we have been developing is currently able to continuously measure stable water isotopes 3) and electrolytic conductivity, as well as to collect discrete samples for the both inner and outer areas with variable depth resolutions. Chemistry analyses4) and methane-gas analysis 5) are planned to be added using the continuous water stream system 5). In order to optimize the resolution of the current system with minimal sample volumes necessary for different analyses, our CFA system typically melts an ice core at 1.6 cm/min. Instead of using a wire position encoder with typical 1mm positioning resolution 6), we decided to use a high-accuracy CCD Laser displacement sensor (LKG-G505, Keyence). At the 1.6 cm/min melt rate, the positioning resolution was increased to 0.27mm. Also, the mixing volume that occurs in our open split debubbler is regulated using its weight. The overflow pumping rate is smoothly PID controlled to maintain the weight as low as possible, while keeping a safety buffer of water to avoid air bubbles downstream. To evaluate the system's depth-resolution, we will present the preliminary data of electrolytic conductivity obtained by melting 12 bags of the North Greenland Eemian Ice Drilling (NEEM) ice core. The samples correspond to different climate intervals (Greenland Stadial 21, 22, Greenland Stadial 5, Greenland Interstadial 5, Greenland Interstadial 7, Greenland Stadial 8). We will present results for the Greenland Stadial -8, whose depths and ages are between 1723.7 and 1724.8 meters, and 35.520 to

  19. Precision glass molding of high-resolution diffractive optical elements

    Science.gov (United States)

    Prater, Karin; Dukwen, Julia; Scharf, Toralf; Herzig, Hans P.; Plöger, Sven; Hermerschmidt, Andreas

    2016-04-01

    The demand of high resolution diffractive optical elements (DOE) is growing. Smaller critical dimensions allow higher deflection angles and can fulfill more demanding requirements, which can only be met by using electron-beam lithography. Replication techniques are more economical, since the high cost of the master can be distributed among a larger number of replicas. The lack of a suitable mold material for precision glass molding has so far prevented an industrial use. Glassy Carbon (GC) offers a high mechanical strength and high thermal strength. No anti-adhesion coatings are required in molding processes. This is clearly an advantage for high resolution, high aspect ratio microstructures, where a coating with a thickness between 10 nm and 200 nm would cause a noticeable rounding of the features. Electron-beam lithography was used to fabricate GC molds with highest precision and feature sizes from 250 nm to 2 μm. The master stamps were used for precision glass molding of a low Tg glass L-BAL42 from OHARA. The profile of the replicated glass is compared to the mold with the help of SEM images. This allows discussion of the max. aspect-ratio and min. feature size. To characterize optical performances, beamsplitting elements are fabricated and their characteristics were investigated, which are in excellent agreement to theory.

  20. Design and development of a high resolution animal SPECT scanner dedicated for rat and mouse imaging

    Energy Technology Data Exchange (ETDEWEB)

    Sajedi, Salar; Zeraatkar, Navid [Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran (Iran, Islamic Republic of); Moji, Vahideh; Farahani, Mohammad Hossein [Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran (Iran, Islamic Republic of); Parto Negar Persia Co, Tehran (Iran, Islamic Republic of); Sarkar, Saeed [Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran (Iran, Islamic Republic of); Department of Medical Physics and Biomedical Engineering, Tehran University of Medical Sciences, Tehran (Iran, Islamic Republic of); Arabi, Hossein [Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran (Iran, Islamic Republic of); Teymoorian, Behnoosh [Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran (Iran, Islamic Republic of); Parto Negar Persia Co, Tehran (Iran, Islamic Republic of); Ghafarian, Pardis [Chronic Respiratory Disease Research Center, NRITLD, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran (Iran, Islamic Republic of); PET/CT and Cyclotron Center, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran (Iran, Islamic Republic of); Rahmim, Arman [Department of Radiology, Johns Hopkins University, Baltimore, MD (United States); Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD (United States); Reza Ay, Mohammad, E-mail: mohammadreza_ay@sina.tums.ac.ir [Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran (Iran, Islamic Republic of); Department of Medical Physics and Biomedical Engineering, Tehran University of Medical Sciences, Tehran (Iran, Islamic Republic of)

    2014-03-21

    A dedicated small-animal SPECT system, HiReSPECT, was designed and developed to provide a high resolution molecular imaging modality in response to growing research demands. HiReSPECT is a dual-head system mounted on a rotating gantry. The detection system is based on pixelated CsI(Na) scintillator crystals coupled to two Hamamatsu H8500 Position Sensitive Photomultiplier Tubes in each head. Also, a high resolution parallel-hole collimator is applied to every head. The dimensions of each head are 50 mm×100 mm, enabling sufficient transaxial and axial fields-of-view (TFOV and AFOV), respectively, for coverage of the entire mouse in single-bed position imaging. However, a 50 mm TFOV is not sufficient for transaxial coverage of rats. To address this, each head can be rotated by 90 degrees in order to align the larger dimension of the heads with the short body axis, allowing tomographic data acquisition for rats. An innovative non-linear recursive filter was used for signal processing/detection. Resolution recovery was also embedded in the modified Maximum-Likelihood Expectation Maximization (MLEM) image reconstruction code to compensate for Collimator-Detector Response (CDR). Moreover, an innovative interpolation algorithm was developed to speed up the reconstruction code. The planar spatial resolution at the head surface and the image spatial resolutions were 1.7 mm and 1.2–1.6 mm, respectively. The measurements followed by post-processing showed that the observed count rate at 20% count loss is about 42 kcps. The system sensitivity at the collimator surface for heads 1 and 2 were 1.32 cps/µCi and 1.25 cps/µCi, respectively. The corresponding values were 1.18 cps/µCi and 1.02 cps/µCi at 8 cm distance from the collimator surfaces. In addition, whole-body scans of mice demonstrated appropriate imaging capability of the HiReSPECT.

  1. Calibration of a High Resolution Airborne 3-D SAR

    DEFF Research Database (Denmark)

    Dall, Jørgen; Grinder-Pedersen, Jan; Madsen, S.N.

    1997-01-01

    (EMI). In order to achieve a high geodetic fidelity when using such systems operationally, calibration procedures must be applied. Inaccurate navigation data and system parameters as well as system imperfections must be accounted for. This paper presents theoretical models describing the impact of key......The potential of across-track interferometric (XTI) synthetic aperture radar (SAR) for producing high resolution 3D imagery has been demonstrated by several airborne systems including EMISAR, the dual frequency, polarimetric, and interferometric SAR developed at the Dept. of Electromagnetic Systems...

  2. Coverage Options for a Low cost, High Resolution Optical Constellation

    OpenAIRE

    Price, M E; Levett, W.; Graham, K.

    2003-01-01

    This paper presents the range of coverage options available to TopSat like small satellites, both singly and in a small constellation. TopSat is a low-cost, high resolution and image quality, optical small satellite, due for launch in October 2004. In particular, the paper considers the use of tuned, repeat ground track orbits to improve coverage for selected ground targets, at the expense of global coverage. TopSat is designed to demonstrate the capabilities of small satellites for high valu...

  3. High resolution study of magnetic ordering at absolute zero.

    Science.gov (United States)

    Lee, M; Husmann, A; Rosenbaum, T F; Aeppli, G

    2004-05-07

    High resolution pressure measurements in the zero-temperature limit provide a unique opportunity to study the behavior of strongly interacting, itinerant electrons with coupled spin and charge degrees of freedom. Approaching the precision that has become the hallmark of experiments on classical critical phenomena, we characterize the quantum critical behavior of the model, elemental antiferromagnet chromium, lightly doped with vanadium. We resolve the sharp doubling of the Hall coefficient at the quantum critical point and trace the dominating effects of quantum fluctuations up to surprisingly high temperatures.

  4. High-resolution protein structure determination by serial femtosecond crystallography.

    Science.gov (United States)

    Boutet, Sébastien; Lomb, Lukas; Williams, Garth J; Barends, Thomas R M; Aquila, Andrew; Doak, R Bruce; Weierstall, Uwe; DePonte, Daniel P; Steinbrener, Jan; Shoeman, Robert L; Messerschmidt, Marc; Barty, Anton; White, Thomas A; Kassemeyer, Stephan; Kirian, Richard A; Seibert, M Marvin; Montanez, Paul A; Kenney, Chris; Herbst, Ryan; Hart, Philip; Pines, Jack; Haller, Gunther; Gruner, Sol M; Philipp, Hugh T; Tate, Mark W; Hromalik, Marianne; Koerner, Lucas J; van Bakel, Niels; Morse, John; Ghonsalves, Wilfred; Arnlund, David; Bogan, Michael J; Caleman, Carl; Fromme, Raimund; Hampton, Christina Y; Hunter, Mark S; Johansson, Linda C; Katona, Gergely; Kupitz, Christopher; Liang, Mengning; Martin, Andrew V; Nass, Karol; Redecke, Lars; Stellato, Francesco; Timneanu, Nicusor; Wang, Dingjie; Zatsepin, Nadia A; Schafer, Donald; Defever, James; Neutze, Richard; Fromme, Petra; Spence, John C H; Chapman, Henry N; Schlichting, Ilme

    2012-07-20

    Structure determination of proteins and other macromolecules has historically required the growth of high-quality crystals sufficiently large to diffract x-rays efficiently while withstanding radiation damage. We applied serial femtosecond crystallography (SFX) using an x-ray free-electron laser (XFEL) to obtain high-resolution structural information from microcrystals (less than 1 micrometer by 1 micrometer by 3 micrometers) of the well-characterized model protein lysozyme. The agreement with synchrotron data demonstrates the immediate relevance of SFX for analyzing the structure of the large group of difficult-to-crystallize molecules.

  5. High resolution upgrade of the ATF damping ring BPM system

    Energy Technology Data Exchange (ETDEWEB)

    Terunuma, N.; Urakawa, J.; /KEK, Tsukuba; Frisch, J.; May, J.; McCormick, D.; Nelson, J.; Seryi, A.; Smith, T.; Woodley, M.; /SLAC; Briegel, C.; Dysert, R.; /Fermilab

    2008-05-01

    A beam position monitor (BPM) upgrade at the KEK Accelerator Test Facility (ATF) damping ring has been accomplished in its first stage, carried out by a KEK/FNAL/SLAC collaboration under the umbrella of the global ILC R&D effort. The upgrade consists of a high resolution, high reproducibility read-out system, based on analog and digital downconversion techniques, digital signal processing, and also tests a new automatic gain error correction schema. The technical concept and realization, as well as preliminary results of beam studies are presented.

  6. Localized corrosion information using high resolution measurement devices

    DEFF Research Database (Denmark)

    Ambat, Rajan

    2005-01-01

    to control the solution flow at the tip. Through addition of reference and counter electrodes, the pipette system becomes a microscopic electrochemical cell, which can then be used with high precision to determine the electrochemical characteristics of the microstructural region of interest. The capability...... of the technique could be further enhanced by adding new features such as high resolution video visualization systems, fretting/tribo-corroson attachments, and also by integrating it with stress corrosion testing, corrosion investigation of concrete for a few to name with. The corrosion group in MPT, Technical...

  7. High-resolution multimodal clinical multiphoton tomography of skin

    Science.gov (United States)

    König, Karsten

    2011-03-01

    This review focuses on multimodal multiphoton tomography based on near infrared femtosecond lasers. Clinical multiphoton tomographs for 3D high-resolution in vivo imaging have been placed into the market several years ago. The second generation of this Prism-Award winning High-Tech skin imaging tool (MPTflex) was introduced in 2010. The same year, the world's first clinical CARS studies have been performed with a hybrid multimodal multiphoton tomograph. In particular, non-fluorescent lipids and water as well as mitochondrial fluorescent NAD(P)H, fluorescent elastin, keratin, and melanin as well as SHG-active collagen has been imaged with submicron resolution in patients suffering from psoriasis. Further multimodal approaches include the combination of multiphoton tomographs with low-resolution wide-field systems such as ultrasound, optoacoustical, OCT, and dermoscopy systems. Multiphoton tomographs are currently employed in Australia, Japan, the US, and in several European countries for early diagnosis of skin cancer, optimization of treatment strategies, and cosmetic research including long-term testing of sunscreen nanoparticles as well as anti-aging products.

  8. Radiation length imaging with high-resolution telescopes

    Science.gov (United States)

    Stolzenberg, U.; Frey, A.; Schwenker, B.; Wieduwilt, P.; Marinas, C.; Lütticke, F.

    2017-02-01

    The construction of low mass vertex detectors with a high level of system integration is of great interest for next generation collider experiments. Radiation length images with a sufficient spatial resolution can be used to measure and disentangle complex radiation length X/X0 profiles and contribute to the understanding of vertex detector systems. Test beam experiments with multi GeV particle beams and high-resolution tracking telescopes provide an opportunity to obtain precise 2D images of the radiation length of thin planar objects. At the heart of the X/X0 imaging is a spatially resolved measurement of the scattering angles of particles traversing the object under study. The main challenges are the alignment of the reference telescope and the calibration of its angular resolution. In order to demonstrate the capabilities of X/X0 imaging, a test beam experiment has been conducted. The devices under test were two mechanical prototype modules of the Belle II vertex detector. A data sample of 100 million tracks at 4 GeV has been collected, which is sufficient to resolve complex material profiles on the 30 μm scale.

  9. Spatial-temperature high resolution map for early cancer diagnosis

    Science.gov (United States)

    Gavriloaia, Gheorghe V.; Hurduc, Anca; Ghimigean, Ana-Maria; Fumarel, Radu

    2009-02-01

    Heat is one of the most important parameters of living beings. Skin temperature is not the same on the entire body and so, a thermal signature can be got. Infrared map on serial imaging can constitute an early sign of an abnormality. Thermography detects changes in tissue that appear before and accompany many diseases including cancer. As this map has a better resolution an early cancer diagnosis can be done. The temperature of neoplasic tissue is different up to 1.5 °C than that of the healthy tissue as a result of the specific metabolic rate. The infrared camera images show very quickly the heat transferred by radiation. A lot of factors disturb the temperature conversion to pixel intensity. A sensitive temperature sensor with a 10 Mpixels video camera, showing its spatial position, and a computer fusion program were used for the map with high spatial-temperature resolution. A couple of minutes are necessary to get a high resolution map. The asymmetry and borders were the main parameters analyzed. The right cancer diagnosis was for about 78.4% of patients with thyroid cancer, and more than 89.6% from patients with breast cancer. In the near future, the medical prognosis will be improved by fractal analysis.

  10. Polystyrene negative resist for high-resolution electron beam lithography

    Directory of Open Access Journals (Sweden)

    Ma Siqi

    2011-01-01

    Full Text Available Abstract We studied the exposure behavior of low molecular weight polystyrene as a negative tone electron beam lithography (EBL resist, with the goal of finding the ultimate achievable resolution. It demonstrated fairly well-defined patterning of a 20-nm period line array and a 15-nm period dot array, which are the densest patterns ever achieved using organic EBL resists. Such dense patterns can be achieved both at 20 and 5 keV beam energies using different developers. In addition to its ultra-high resolution capability, polystyrene is a simple and low-cost resist with easy process control and practically unlimited shelf life. It is also considerably more resistant to dry etching than PMMA. With a low sensitivity, it would find applications where negative resist is desired and throughput is not a major concern.

  11. A new matching algorithm for high resolution mass spectra

    DEFF Research Database (Denmark)

    Hansen, Michael Edberg; Smedsgaard, Jørn

    2004-01-01

    We present a new matching algorithm designed to compare high-resolution spectra. Whereas existing methods are bound to compare fixed intervals of ion masses, the accurate mass spectrum (AMS) distance method presented here is independent of any alignment. Based on the Jeffreys-Matusitas (JM......) distance, a difference between observed peaks across pairs of spectra can be calculated, and used to find a unique correspondence between the peaks. The method takes into account that there may be differences in resolution of the spectra. The algorithm is used for indexing in a database containing 80...... accurate mass spectra from an analysis of extracts of 80 isolates representing the nine closely related species in the Penicillium series Viridicata. Using this algorithm we can obtain a retrieval performance of approximate to97-98% that is comparable with the best of the existing methods (e.g., the dot...

  12. Observations of solar scattering polarization at high spatial resolution

    CERN Document Server

    Snik, F; Ichimoto, K; Fischer, C E; Keller, C U; Lites, B W

    2010-01-01

    The weak, turbulent magnetic fields that supposedly permeate most of the solar photosphere are difficult to observe, because the Zeeman effect is virtually blind to them. The Hanle effect, acting on the scattering polarization in suitable lines, can in principle be used as a diagnostic for these fields. However, the prediction that the majority of the weak, turbulent field resides in intergranular lanes also poses significant challenges to scattering polarization observations because high spatial resolution is usually difficult to attain. We aim to measure the difference in scattering polarization between granules and intergranules. We present the respective center-to-limb variations, which may serve as input for future models. We perform full Stokes filter polarimetry at different solar limb positions with the CN band filter of the Hinode-SOT Broadband Filter Imager, which represents the first scattering polarization observations with sufficient spatial resolution to discern the granulation. Hinode-SOT offer...

  13. High resolution capacitance detection circuit for rotor micro-gyroscope

    Directory of Open Access Journals (Sweden)

    Ming-Yuan Ren

    2014-03-01

    Full Text Available Conventional methods for rotor position detection of micro-gyroscopes include common exciting electrodes (single frequency and common sensing electrodes (frequency multiplex, but they have encountered some problems. So we present a high resolution and low noise pick-off circuit for micro-gyroscopes which utilizes the time multiplex method. The detecting circuit adopts a continuous-time current sensing circuit for capacitance measurement, and its noise analysis of the charge amplifier is introduced. The equivalent output noise power spectral density of phase-sensitive demodulation is 120 nV/Hz1/2. Tests revealed that the whole circuitry has a relative capacitance resolution of 1 × 10−8.

  14. High resolution ultrasound and photoacoustic imaging of single cells.

    Science.gov (United States)

    Strohm, Eric M; Moore, Michael J; Kolios, Michael C

    2016-03-01

    High resolution ultrasound and photoacoustic images of stained neutrophils, lymphocytes and monocytes from a blood smear were acquired using a combined acoustic/photoacoustic microscope. Photoacoustic images were created using a pulsed 532 nm laser that was coupled to a single mode fiber to produce output wavelengths from 532 nm to 620 nm via stimulated Raman scattering. The excitation wavelength was selected using optical filters and focused onto the sample using a 20× objective. A 1000 MHz transducer was co-aligned with the laser spot and used for ultrasound and photoacoustic images, enabling micrometer resolution with both modalities. The different cell types could be easily identified due to variations in contrast within the acoustic and photoacoustic images. This technique provides a new way of probing leukocyte structure with potential applications towards detecting cellular abnormalities and diseased cells at the single cell level.

  15. High-resolution infrared observations of active galactic nuclei

    Science.gov (United States)

    Pott, Jörg-Uwe

    2012-07-01

    Interferometric resolution at IR wavelengths offers for the first time the possibility to zoom into the nuclei of galaxies beyond the circumnuclear stellar structures and spatially resolve gas and dust in the innermost regions (0.05-5pc), dominated by the central black hole. Ultimate goal is to reveal new aspects of AGN feeding, and interaction with its host galaxy. After first successes of resolving AGN with infrared interferometry (VLTI, Keck-IF), the second generation of high-resolution interferometric imagers behind 8m class telescopes is currently being built. I will summarize current aspects and successes of the field, and present our activities to provide extended capabilities for VLTI-Midi and -Matisse, LBT-Linc-Nirvana and Keck-Astra to study a larger sample of AGN in greater detail.

  16. High resolution ultrasound and photoacoustic imaging of single cells

    Directory of Open Access Journals (Sweden)

    Eric M. Strohm

    2016-03-01

    Full Text Available High resolution ultrasound and photoacoustic images of stained neutrophils, lymphocytes and monocytes from a blood smear were acquired using a combined acoustic/photoacoustic microscope. Photoacoustic images were created using a pulsed 532 nm laser that was coupled to a single mode fiber to produce output wavelengths from 532 nm to 620 nm via stimulated Raman scattering. The excitation wavelength was selected using optical filters and focused onto the sample using a 20× objective. A 1000 MHz transducer was co-aligned with the laser spot and used for ultrasound and photoacoustic images, enabling micrometer resolution with both modalities. The different cell types could be easily identified due to variations in contrast within the acoustic and photoacoustic images. This technique provides a new way of probing leukocyte structure with potential applications towards detecting cellular abnormalities and diseased cells at the single cell level.

  17. High-resolution proper motions in a sunspot penumbra

    CERN Document Server

    Márquez, I; Bonet, J A

    2006-01-01

    Local correlation tracking techniques are used to measure proper motions in a series of high angular resolution (~0.1 arcsec) penumbra images. If these motions trace true plasma motions, then we have detected converging flows that arrange the plasma in long narrow filaments co-spatial with dark penumbral filaments. Assuming that these flows are stationary, the vertical stratification of the atmosphere and the conservation of mass suggest downflows in the filaments of the order of 200 m/s. The association between downflows and dark features may be a sign of convection, as it happens with the non-magnetic granulation. Insufficient spatial resolution may explain why the estimated vertical velocities are not fast enough to supply the radiative losses of penumbrae.

  18. Microcalorimetry for High-Resolution X-Ray Spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Friedrich, Stephen [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-01-03

    Magnetic Microcalorimeters (MMCs) are gamma-ray detectors with an energy resolution 10x higher than high-purity germanium detectors. They can increase the accuracy of non-destructive analysis of nuclear materials, enable the detection of new isotopes (e.g. Pu-242 of U-236), and improve nuclear data in cases where Ge detectors are limited by line overlap. MMCs consist of a magnetic sensor operated at temperatures below 50 mK, and they infer gamma-ray energies from the change in magnetization due to the temperature increase after gamma-ray absorption. The goal of this project is to further increase the energy resolution and sensitivity of MMC gamma detectors.

  19. High-resolution NMR imaging of the hand

    Energy Technology Data Exchange (ETDEWEB)

    Koenig, H.; Lucas, D.

    1986-12-01

    With high spatial resolution guaranteed, NMR imaging allows to simultaneously make visible the complex osseous, chondral, and ligamentous structures of the hand. The examinations reported on were made with a 1.0 Tesla Magnetom using a special surface coil so as to achieve cut heights of 3-4 mm and an in-plane resolution of 0.5 mm. In addition to normal test persons, 29 patients were examined who had pseudoarthrosis of the os naviculare, lunatomalacia, rheumatic arthritis, or bone and soft-tissue tumors. Comparison with X-ray radiography or bone scintiscans showed that NMR imaging is capable of demonstrating localisation and extension of bone marrow or bone joint abnormalities at an earlier stage.

  20. High-resolution friction force microscopy under electrochemical control

    Science.gov (United States)

    Labuda, Aleksander; Paul, William; Pietrobon, Brendan; Lennox, R. Bruce; Grütter, Peter H.; Bennewitz, Roland

    2010-08-01

    We report the design and development of a friction force microscope for high-resolution studies in electrochemical environments. The design choices are motivated by the experimental requirements of atomic-scale friction measurements in liquids. The noise of the system is analyzed based on a methodology for the quantification of all the noise sources. The quantitative contribution of each noise source is analyzed in a series of lateral force measurements. Normal force detection is demonstrated in a study of the solvation potential in a confined liquid, octamethylcyclotetrasiloxane. The limitations of the timing resolution of the instrument are discussed in the context of an atomic stick-slip measurement. The instrument is capable of studying the atomic friction contrast between a bare Au(111) surface and a copper monolayer deposited at underpotential conditions in perchloric acid.

  1. High-resolution multiphoton imaging of tumors in vivo.

    Science.gov (United States)

    Wyckoff, Jeffrey; Gligorijevic, Bojana; Entenberg, David; Segall, Jeffrey; Condeelis, John

    2011-10-01

    Analysis of the individual steps in metastasis is crucial if insights at the molecular level are to be linked to the cell biology of cancer. A technical hurdle to achieving the analysis of the individual steps of metastasis is the fact that, at the gross level, tumors are heterogeneous in both animal models and patients. Human primary tumors show extensive variation in all properties ranging from growth and morphology of the tumor through tumor-cell density in the blood and formation and growth of metastases. Methods capable of the direct visualization and analysis of tumor-cell behavior at single-cell resolution in vivo have become crucial in advancing the understanding of mechanisms of metastasis, the definition of microenvironment, and the markers related to both. This article discusses the use of high-resolution multiphoton imaging of tumors (specifically breast tumors in mice) in vivo.

  2. High spatial resolution soft-x-ray microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Meyer-Ilse, W.; Medecki, H.; Brown, J.T. [Ernest Orlando Lawrence Berkeley National Lab., CA (United States)] [and others

    1997-04-01

    A new soft x-ray microscope (XM-1) with high spatial resolution has been constructed by the Center for X-ray Optics. It uses bending magnet radiation from beamline 6.1 at the Advanced Light Source, and is used in a variety of projects and applications in the life and physical sciences. Most of these projects are ongoing. The instrument uses zone plate lenses and achieves a resolution of 43 nm, measured over 10% to 90% intensity with a knife edge test sample. X-ray microscopy permits the imaging of relatively thick samples, up to 10 {mu}m thick, in water. XM-1 has an easy to use interface, that utilizes visible light microscopy to precisely position and focus the specimen. The authors describe applications of this device in the biological sciences, as well as in studying industrial applications including structured polymer samples.

  3. Range ambiguity resolution for high PRF pulse-Doppler radar

    Science.gov (United States)

    Postema, G. B.

    The range ambiguity resolution for high 'PRF pulse-Doppler radars can be resolved using a simple algorithm based on residue arithmetic. The unambiguous range is found from R = T + R(a), where T is the output of a look-up table and R(a) is one of the measured ambiguous ranges. This formula is easily extended to multiple PRF ranging systems, where three or more measurements are required for the ambiguity resolution. Target obscuration in clutter reduces the visibility and leads, especially in dense target environments, to ghost ranges. It is shown that long range coverage requires a small resolved pulse length and PRFs as low as practical in the intended clutter and target environment. Special attention is given to the generation of sparsely populated look-up tables that reduce the ghosting problem. A practical example for an S-band surveillance radar is presented.

  4. High-Resolution Characterization of UMo Alloy Microstructure

    Energy Technology Data Exchange (ETDEWEB)

    Devaraj, Arun [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kovarik, Libor [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Joshi, Vineet V. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Jana, Saumyadeep [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Manandhar, Sandeep [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Arey, Bruce W. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Lavender, Curt A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-11-30

    This report highlights the capabilities and procedure for high-resolution characterization of UMo fuels in PNNL. Uranium-molybdenum (UMo) fuel processing steps, from casting to forming final fuel, directly affect the microstructure of the fuel, which in turn dictates the in-reactor performance of the fuel under irradiation. In order to understand the influence of processing on UMo microstructure, microstructure characterization techniques are necessary. Higher-resolution characterization techniques like transmission electron microscopy (TEM) and atom probe tomography (APT) are needed to interrogate the details of the microstructure. The findings from TEM and APT are also directly beneficial for developing predictive multiscale modeling tools that can predict the microstructure as a function of process parameters. This report provides background on focused-ion-beam–based TEM and APT sample preparation, TEM and APT analysis procedures, and the unique information achievable through such advanced characterization capabilities for UMo fuels, from a fuel fabrication capability viewpoint.

  5. High-Resolution, Wide-Field-of-View Scanning Telescope

    Science.gov (United States)

    Sepulveda, Cesar; Wilson, Robert; Seshadri, Suresh

    2007-01-01

    A proposed telescope would afford high resolution over a narrow field of view (<0.10 ) while scanning over a total field of view nominally 16 wide without need to slew the entire massive telescope structure. The telescope design enables resolution of a 1-m-wide object in a 50- km-wide area of the surface of the Earth as part of a 200-km-wide area field of view monitored from an orbit at an altitude of 700 km. The conceptual design of this telescope could also be adapted to other applications both terrestrial and extraterrestrial in which there are requirements for telescopes that afford both wide- and narrow-field capabilities. In the proposed telescope, the scanning would be effected according to a principle similar to that of the Arecibo radio telescope, in which the primary mirror is stationary with respect to the ground and a receiver is moved across the focal surface of the primary mirror. The proposed telescope would comprise (1) a large spherical primary mirror that would afford high resolution over a narrow field of view and (2) a small displaceable optical relay segment that would be pivoted about the center of an aperture stop to effect the required scanning (see figure). Taken together, both comprise a scanning narrow-angle telescope that does not require slewing the telescope structure. In normal operation, the massive telescope structure would stare at a fixed location on the ground. The inner moveable relay optic would be pivoted to scan the narrower field of view over the wider one, making it possible to retain a fixed telescope orientation, while obtaining high-resolution images over multiple target areas during an interval of 3 to 4 minutes in the intended orbit. The pivoting relay segment of the narrow-angle telescope would include refractive and reflective optical elements, including two aspherical mirrors, to counteract the spherical aberration of the primary mirror. Overall, the combination of the primary mirror and the smaller relay optic

  6. High Resolution Infrared Spectroscopy of Allene -D4.

    Science.gov (United States)

    Rousan, Khetam Ibrahim Khasawinah

    Two parallel bands of allene-d(,4), (nu)(,6) (occurring at 1920.2289 cm('-1)) and (nu)(,5) (occurring at 2228.4133 cm('-1)), and the perpendicular band, (nu)(,8) (occurring at 2321.2484 cm('-1)), were recorded by using two spectrometers under high resolution. The combination band, (nu)(,2) + (nu)(,7), was measured also; the band origin is located at 2276.0053 cm('-1), rather distant from the previously reported one at 2267.0 cm('-1). Initially, by using the 4.5 m grating spectrometer, deconvolution of the spectra achieved a resolution of (TURN)0.007 cm('-1). Although the resolution was high, a detailed analysis of the K structure could not be obtained. Other measurements were carried out by using a BOMEM Fourier transform spectrometer. Deconvolution of the spectra achieved a resolution of (TURN)0.002 cm(' -1). This made it possible to resolve and analyze these bands in detail. Successful ground state and upper state analyses were completed from this data. Combining all the three bands together, a ground state analysis has resulted in better values of. (DIAGRAM, TABLE OR GRAPHIC OMITTED...PLEASE SEE DAI). than the previously published works on the same molecule by others. A set of accurate spectroscopic constants was obtained for each band. The spectrum of the (nu)(,8) band was analyzed in detail, including the perturbations. The perturbed states for (nu)(,8) were assigned as 2(nu)(,9) + (nu)(,10), (nu)(,2) + (nu)(,9) + (nu)(,11) and 2(nu)(,3) + (nu)(,4), and the spectroscopic constants for those perturbed states were calculated.

  7. Build Axial Gradient Field by Using Axial Magnetized Permanent Rings

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Axial magnetic field produced by an axial magnetized permanent ring was studied. For two permanent rings, if they are magnetized in the same directions, a nearly uniform axial field can be produced. If they are magnetized in opposite direction,an axial gradient magnetic field can be generated, with the field range changing from -B0 to B0. A permanent magnet with a high axial gradient field was fabricated, the measured results agree with the PANDIRA calculation very well. For wider usage,it is desirable for the field gradient to be changed. Some methods to produce the variable gradient field are presented. These kinds of axial gradient magnetic field can also be used as a beam focusing for linear accelerator if the periodic field can be produced along the beam trajectory. The axial magnetic field is something like a solenoid, large stray field will leak to the outside environment if no method is taken to control them. In this paper, one method is illustrated to shield off the outside leakage field.

  8. High-resolution flying-PIV with optical fiber laser delivery

    Science.gov (United States)

    Weichselbaum, Noah A.; André, Matthieu A.; Rahimi-Abkenar, Morteza; Manzari, Majid T.; Bardet, Philippe M.

    2016-05-01

    Implementation of non-intrusive optical measurement techniques, such as particle image velocimetry (PIV), in harsh environments requires specialized techniques for introducing controlled laser sheets to the region of interest. Large earthquake shake tables are a particularly challenging environment. Lasers must be mounted away from the table, and the laser sheet has to be delivered precisely and stably to the measurement station. Here, high-power multi-mode step-index fiber optics enable introduction of light from an Nd:YLF pulsed laser to a remote test section. Such lasers are suitable for coupling to optical fibers, which presents a portable, flexible, and safe manner to deliver a PIV light sheet. Best practices for their implementation are reviewed. Particular attention is focused on obtaining a collimated beam of acceptable quality at the output of the fiber. To achieve high spatial resolution, the PIV camera is directly mounted on the moving shake table with care to minimize its vibrations. A special arrangement of PIV planes is deployed for precise in-situ PIV alignment and to monitor and account for residual structure vibrations and beam wandering. The design of the instruments is detailed. Here, an experimental facility for the study of nuclear fuel bundle response to seismic forcing near prototypical conditions is instrumented. Only through integration of a high-resolution flying-PIV system can velocity fields be acquired. Data indicate that in the presence of a mean axial flow, a secondary oscillatory flow develops as the bundle oscillates. Instantaneous, phase-averaged, and fluctuating velocity fields illustrate this phenomenon.

  9. Polyfluorene nanowires with pronounced axial texturing prepared by melt-assisted template wetting

    Energy Technology Data Exchange (ETDEWEB)

    O' Carroll, Deirdre; Irwin, Jennifer [Nanotechnology Group, Tyndall National Institute, Lee Maltings, Prospect Row, Cork (Ireland); Tanner, David A. [Department of Manufacturing and Operations Engineering, Materials and Surface Science Institute, University of Limerick, Limerick (Ireland); Redmond, Gareth [Nanotechnology Group, Tyndall National Institute, Lee Maltings, Prospect Row, Cork (Ireland)], E-mail: gareth.redmond@tyndall.ie

    2008-02-15

    Poly(9,9-dioctylfluorene) conjugated polymer nanowires were fabricated by melt-assisted wetting of porous anodic alumina templates. Analysis by high-resolution transmission electron microscopy and X-ray diffraction suggested that the polymer molecules were axially textured within the nanowires. Polarized optical microscopy images of single nanowires exhibited a pronounced optical birefringence consistent with internal axial alignment of the polymer molecules. Polarization-resolved photoluminescence images and spectra were acquired following near-field optical addressing of single nanowires. This data revealed that nanowire luminescence was markedly anisotropic with a preferred axial polarization of wire emission.

  10. High-resolution absorption measurements of NH3 at high temperatures: 500–2100cm−1

    DEFF Research Database (Denmark)

    Barton, Emma J.; Yurchenko, Sergei N.; Tennyson, Jonathan

    2015-01-01

    High-resolution absorption spectra of NH3 in the region 500–2100 cm -1 at temperatures up to1027 1C and approximately atmospheric pressure (1013±20 mbar) are measured. NH3 concentrations of 1000 ppm,0.5% and 1% in volume fraction were used in the measurements. Spectra are recorded in high...... temperature gas flow cells using a FourierTransform Infrared (FTIR) spectrometer at a nominal resolution of 0.09cm-1. Measurements at 22.7 °C are compared to high-resolution cross sections available from thePacific Northwest National Laboratory (PNNL). The higher temperature spectra are analysed by comparison...

  11. On high-resolution manoeuvres control via trajectory optimization

    Indian Academy of Sciences (India)

    A H MAZINAN; M SHAHI

    2017-02-01

    This research is on a realization of control approach in line with the trajectory optimization for the purpose of dealing with overactuated spacecraft in the process of the high-resolution manoeuvres. The idea behind the research is to realize closed control loops to cope with the rotational angles and the corresponding angular rates,synchronously, to handle the spacecraft manoeuvres. It is to be noted that the traditional techniques may not have sufficient merit to deal with such a complicated process, suitably. The proposed trajectory optimization is designed to provide the three-axis referenced commands, in finite burn, for transferring the aforementioned overactuated spacecraft from the initial orbit to its final outcomes in the orbital transfer process. The outcomes are realized through the variations of the orbital parameters, including the inclination, the eccentricity, the angular momentum, the semi-major axis and so on, in the high-resolution manoeuvres. It aims to get the system under control to guarantee the performance of the three-dimensional rotational angles tracking to be desirable, instantly. The contribution of the research is to make the high-thrust optimization trajectory,which is organized in association with the new configuration of the three-axis attitude control approach, to be applicable to manage the present overactuated spacecraft in the procedure of high-resolution orbital transfer process. The investigated outcomes of the research are efficient and competitive along with the potential materials through a series of experiments, as long as the desirable tracking performance in the three-dimensional space manoeuvres is apparently guaranteed.

  12. Fusing visual and clinical information for lung tissue classification in high-resolution computed tomography.

    Science.gov (United States)

    Depeursinge, Adrien; Racoceanu, Daniel; Iavindrasana, Jimison; Cohen, Gilles; Platon, Alexandra; Poletti, Pierre-Alexandre; Müller, Henning

    2010-09-01

    We investigate the influence of the clinical context of high-resolution computed tomography (HRCT) images of the chest on tissue classification. 2D regions of interest in HRCT axial slices from patients affected with an interstitial lung disease are automatically classified into five classes of lung tissue. Relevance of the clinical parameters is studied before fusing them with visual attributes. Two multimedia fusion techniques are compared: early versus late fusion. Early fusion concatenates features in one single vector, yielding a true multimedia feature space. Late fusion consisting of the combination of the probability outputs of two support vector machines. The late fusion scheme allowed a maximum of 84% correct predictions of testing instances among the five classes of lung tissue. This represents a significant improvement of 10% compared to a pure visual-based classification. Moreover, the late fusion scheme showed high robustness to the number of clinical parameters used, which suggests that it is appropriate for mining clinical attributes with missing values in clinical routine. Copyright (c) 2010 Elsevier B.V. All rights reserved.

  13. Full-sky, High-resolution Maps of Interstellar Dust

    Science.gov (United States)

    Meisner, Aaron Michael

    We present full-sky, high-resolution maps of interstellar dust based on data from the Wide-field Infrared Survey Explorer (WISE) and Planck missions. We describe our custom processing of the entire WISE 12 micron All-Sky imaging data set, and present the resulting 15 arcsecond resolution, full-sky map of diffuse Galactic dust emission, free of compact sources and other contaminating artifacts. Our derived 12 micron dust map offers angular resolution far superior to that of all other existing full-sky, infrared dust emission maps, revealing a wealth of small-scale filamentary structure. We also apply the Finkbeiner et al. (1999) two-component thermal dust emission model to the Planck HFI maps. We derive full-sky 6.1 arcminute resolution maps of dust optical depth and temperature by fitting this two-component model to Planck 217-857 GHz along with DIRBE/IRAS 100 micron data. In doing so, we obtain the first ever full-sky 100-3000 GHz Planck-based thermal dust emission model, as well as a dust temperature correction with ~10 times enhanced angular resolution relative to DIRBE-based temperature maps. Analyzing the joint Planck/DIRBE dust spectrum, we show that two-component models provide a better fit to the 100-3000 GHz emission than do single-MBB models, though by a lesser margin than found by Finkbeiner et al. (1999) based on FIRAS and DIRBE. We find that, in diffuse sky regions, our two-component 100-217 GHz predictions are on average accurate to within 2.2%, while extrapolating the Planck Collaboration (2013) single-MBB model systematically underpredicts emission by 18.8% at 100 GHz, 12.6% at 143 GHz and 7.9% at 217 GHz. We calibrate our two-component optical depth to reddening, and compare with reddening estimates based on stellar spectra. We find the dominant systematic problems in our temperature/reddening maps to be zodiacal light on large angular scales and the cosmic infrared background anisotropy on small angular scales. Future work will focus on combining

  14. Tolerancing of a carbon fiber reinforced polymer metering tube structure of a high-resolution space-borne telescope

    Science.gov (United States)

    Ekinci, Mustafa

    2016-07-01

    High resolution space borne telescopes require dimensionally stable structures to meet very stringent optical requirements. Furthermore, high resolution space borne telescope structures need to have high stiffness and be lightweight in order to survive launch loads. Carbon fiber reinforced polymers (CFRP) are lightweight and have tailorable mechanical properties like stiffness and coefficient of thermal expansion. However, mechanical properties are highly dependent on manufacturing processes and manufacturing precision. Moreover CFRP tend to absorb moisture which affects dimensional stability of the structure in the vacuum environment. In order to get specified properties out of manufacturing, tolerances need to be defined very accurately. In this paper, behavior of CFRP metering tube structure of a high resolution space borne camera is investigated for ply orientation, fiber and void content deviations which may arise from manufacturing errors and limitations. A computer code is generated to determine laminate properties of stacked up uni-directional (UD) laminae using classical laminate theory with fiber and matrix properties obtained from suppliers and literature. After defining laminate stackup, many samples are virtually created with ply orientations, volumetric fiber and void content that randomly deviates in a tolerance range which will be used in manufacturing. Normal distribution, standard deviation and mean values are presented for elasticity modulus, coefficient of thermal expansion (CTE), coefficient of moisture expansion (CME) and thermal conductivity in axial and transverse directions of quasi-isotropic stackups and other stackups which have properties presented in literature.

  15. High Resolution Energetic X-ray Imager (HREXI)

    Science.gov (United States)

    Grindlay, Jonathan

    We propose to design and build the first imaging hard X-ray detector system that incorporates 3D stacking of closely packed detector readouts in finely-spaced imaging arrays with their required data processing and control electronics. In virtually all imaging astronomical detectors, detector readout is done with flex connectors or connections that are not vertical but rather horizontal , requiring loss of focal plane area. For high resolution pixel detectors needed for high speed event-based X-ray imaging, from low energy applications (CMOS) with focusing X-ray telescopes, to hard X-ray applications with pixelated CZT for large area coded aperture telescopes, this new detector development offers great promise. We propose to extend our previous and current APRA supported ProtoEXIST program that has developed the first large area imaging CZT detectors and demonstrated their astrophysical capabilities on two successful balloon flight to a next generation High Resolution Energetic X-ray Imager (HREXI), which would incorporate microvia technology for the first time to connect the readout ASIC on each CZT crystal directly to its control and data processing system. This 3-dimensional stacking of detector and readout/control system means that large area (>2m2) imaging detector planes for a High Resolution Wide-field hard X-ray telescope can be built with initially greatly reduced detector gaps and ultimately with no gaps. This increases detector area, efficiency, and simplicity of detector integration. Thus higher sensitivity wide-field imagers will be possible at lower cost. HREXI will enable a post-Swift NASA mission such as the EREXS concept proposed to PCOS to be conducted as a future MIDEX mission. This mission would conduct a high resolution (<2 arcmin) , broad band (5 200 keV) hard X-ray survey of black holes on all scales with ~10X higher sensitivity than Swift. In the current era of Time Domain Astrophysics, such a survey capability, in conjunction with a n

  16. High-Resolution Mammography Detector Employing Optical Switching Readout

    Science.gov (United States)

    Irisawa, Kaku; Kaneko, Yasuhisa; Yamane, Katsutoshi; Sendai, Tomonari; Hosoi, Yuichi

    Conceiving a new detector structure, FUJIFILM Corporation has successfully put its invention of an X-ray detector employing "Optical Switching" into practical use. Since Optical Switching Technology allows an electrode structure to be easily designed, both high resolution of pixel pitch and low electrical noise readout have been achieved, which have consequently realized the world's smallest pixel size of 50×50 μm2 from a Direct-conversion FPD system as well as high DQE. The digital mammography system equipped with this detector enables to acquire high definition images while maintaining granularity. Its outstanding feature is to be able to acquire high-precision images of microcalcifications which is an important index in breast examination.

  17. SPIDER Progress Towards High Resolution Correlated Fission Product Data

    Science.gov (United States)

    Shields, Dan; Meierbachtol, Krista; Tovesson, Fredrik; Arnold, Charles; Blackeley, Rick; Bredeweg, Todd; Devlin, Matt; Hecht, Adam; Jandel, Marian; Jorgenson, Justin; Nelson, Ron; White, Morgan; Spider Team

    2014-09-01

    The SPIDER detector (SPectrometer for Ion DEtermination in fission Research) is under development with the goal of obtaining high-resolution, high-efficiency, correlated fission product data needed for many applications including the modeling of next generation nuclear reactors, stockpile stewardship, and the fundamental understanding of the fission process. SPIDER simultaneously measures velocity and energy of both fission products to calculate fission product yields (FPYs), neutron multiplicity (ν), and total kinetic energy (TKE). A detailed description of the prototype SPIDER detector components will be presented. Characterization measurements with alpha and spontaneous fission sources will also be discussed. LA-UR-14-24875. The SPIDER detector (SPectrometer for Ion DEtermination in fission Research) is under development with the goal of obtaining high-resolution, high-efficiency, correlated fission product data needed for many applications including the modeling of next generation nuclear reactors, stockpile stewardship, and the fundamental understanding of the fission process. SPIDER simultaneously measures velocity and energy of both fission products to calculate fission product yields (FPYs), neutron multiplicity (ν), and total kinetic energy (TKE). A detailed description of the prototype SPIDER detector components will be presented. Characterization measurements with alpha and spontaneous fission sources will also be discussed. LA-UR-14-24875. This work is in part supported by LANL Laboratory Directed Research and Development Projects 20110037DR and 20120077DR.

  18. Multifractal analysis of high resolution solar wind proton density measurements

    Science.gov (United States)

    Sorriso-Valvo, Luca; Carbone, Francesco; Leonardis, Ersilia; Chen, Christopher H. K.; Šafránková, Jana; Němeček, Zdenek

    2017-03-01

    The solar wind is a highly turbulent medium, with a high level of field fluctuations throughout a broad range of scales. These include an inertial range where a turbulent cascade is assumed to be active. The solar wind cascade shows intermittency, which however may depend on the wind conditions. Recent observations have shown that ion-scale magnetic turbulence is almost self-similar, rather than intermittent. A similar result was observed for the high resolution measurements of proton density provided by the spacecraft Spektr-R. Intermittency may be interpreted as the result of the multifractal properties of the turbulent cascade. In this perspective, this paper is devoted to the description of the multifractal properties of the high resolution density measurements. In particular, we have used the standard coarse-graining technique to evaluate the generalized dimensions Dq , and from these the multifractal spectrum f (α) , in two ranges of scale. A fit with the p-model for intermittency provided a quantitative measure of multifractality. Such indicator was then compared with alternative measures: the width of the multifractal spectrum, the peak of the kurtosis, and its scaling exponent. The results indicate that the small-scale fluctuations are multifractal, and suggest that different measures of intermittency are required to fully understand the small scale cascade.

  19. Design of wide field and high resolution video lens

    Science.gov (United States)

    Xiao, Ze-xin; Zhan, Binzhou; Han, Haimei

    2009-11-01

    Online detecting is increasingly used in industrial process for the requirement of product quality improving. It is a trend that the "machine detecting" with "machine version + computer intelligence" as new method replaces traditional manual "eye observation". The essential of "machine detecting" is that image of object being collected with high resolution video lens on sensor panel of photoelectric (CCD ,CMOS) and detecting result being automatically gained by computer after the image saved and processed. "Machine detecting" is developing rapidly with the universal reception by enterprises because of its fine accurateness, high efficiency and the real time. Video lens is one of the important components of machine version system. Requirements of wide field and high resolution enlarged the complexity of video lens design. In this paper a design case used in visible light with field diameter Φ32mm, β=-0.25× and NA'=0.15. We give design parameters of the video lens which obtained with theoretically calculating and Oslo software optimization: MTF>0.3 in full field and 215lp/mm, distortion <0.05%.This lens has an excellent optic performance to match with 1.3 million pixels 1/2"CCD, and a high performance price ratio for being consist of only 7 single lens in the way of 5 units.

  20. A new type of tri-axial accelerometers with high dynamic range MEMS for earthquake early warning

    Science.gov (United States)

    Peng, Chaoyong; Chen, Yang; Chen, Quansheng; Yang, Jiansi; Wang, Hongti; Zhu, Xiaoyi; Xu, Zhiqiang; Zheng, Yu

    2017-03-01

    Earthquake Early Warning System (EEWS) has shown its efficiency for earthquake damage mitigation. As the progress of low-cost Micro Electro Mechanical System (MEMS), many types of MEMS-based accelerometers have been developed and widely used in deploying large-scale, dense seismic networks for EEWS. However, the noise performance of these commercially available MEMS is still insufficient for weak seismic signals, leading to the large scatter of early-warning parameters estimation. In this study, we developed a new type of tri-axial accelerometer based on high dynamic range MEMS with low noise level using for EEWS. It is a MEMS-integrated data logger with built-in seismological processing. The device is built on a custom-tailored Linux 2.6.27 operating system and the method for automatic detecting seismic events is STA/LTA algorithms. When a seismic event is detected, peak ground parameters of all data components will be calculated at an interval of 1 s, and τc-Pd values will be evaluated using the initial 3 s of P wave. These values will then be organized as a trigger packet actively sent to the processing center for event combining detection. The output data of all three components are calibrated to sensitivity 500 counts/cm/s2. Several tests and a real field test deployment were performed to obtain the performances of this device. The results show that the dynamic range can reach 98 dB for the vertical component and 99 dB for the horizontal components, and majority of bias temperature coefficients are lower than 200 μg/°C. In addition, the results of event detection and real field deployment have shown its capabilities for EEWS and rapid intensity reporting.