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Sample records for hh horizontal transmit

  1. Stochastic spatial structured model for vertically and horizontally transmitted infection

    Science.gov (United States)

    Silva, Ana T. C.; Assis, Vladimir R. V.; Pinho, Suani T. R.; Tomé, Tânia; de Oliveira, Mário J.

    2017-02-01

    We study a space structured stochastic model for vertical and horizontal transmitted infection. By means of simple and pair mean-field approximation as well as Monte Carlo simulations, we construct the phase diagram, which displays four states: healthy (H), infected (I), extinct (E), and coexistent (C). In state H only healthy hosts are present, whereas in state I only infected hosts are present. The state E is characterized by the extinction of the hosts whereas in state C there is a coexistence of infected and healthy hosts. In addition to the usual scenario with continuous transition between the I, C and H phases, we found a different scenario with the suppression of the C phase and a discontinuous phase transition between I and H phases.

  2. Transmitted and Reflected Coefficients for Horizontal or Vertical Plate Type Breakwater

    Institute of Scientific and Technical Information of China (English)

    WANG Ke; ZHANG Zhi-qiang; XU Wang

    2011-01-01

    Surface or submerged horizontal or vertical plate can be considered as a new concept breakwater. This paper investigates the wave-plate interaction of this type of breakwater by use of the boundary element method. The relationships of wave transmitted and reflected among plate thickness, submergence and length are carefully studied by numerical simulation. It is shown that: (1) The transmitted coefficients of submerged horizontal plate or vertical plate will become larger with the increase of plate thickness and reduce rapidly with the decrease of plate submergence. (2) Both surface horizontal and vertical plate are efficient for intermediate and short wave elimination, but vertical plate is more effective. (3)Submerged horizontal plate can act more effectively than submerged vertical plate does. With all wave frequencies, the vertical plate almost has no wave elimination effect.

  3. Speed of invasion of an expanding population by a horizontally transmitted trait.

    Science.gov (United States)

    Venegas-Ortiz, Juan; Allen, Rosalind J; Evans, Martin R

    2014-02-01

    Range expansions are a ubiquitous phenomenon, leading to the spatial spread of genetic, ecological, and cultural traits. While some of these traits are advantageous (and hence selected), other, nonselected traits can also spread by hitchhiking on the wave of population expansion. This requires us to understand how the spread of a hitchhiking trait is coupled to the wave of advance of its host population. Here, we use a system of coupled Fisher-Kolmogorov-Petrovsky-Piskunov (F-KPP) equations to describe the spread of a horizontally transmitted hitchhiking trait within a population as it expands. We extend F-KPP wave theory to the system of coupled equations to predict how the hitchhiking trait spreads as a wave within the expanding population. We show that the speed of this trait wave is controlled by an intricate coupling between the tip of the population and trait waves. Our analysis yields a new speed selection mechanism for coupled waves of advance and reveals the existence of previously unexpected speed transitions.

  4. Murine gammaherpesvirus-68 (MHV-68) is not horizontally transmitted amongst laboratory mice by cage contact.

    Science.gov (United States)

    Aligo, Jason; Brosnan, Kerry; Walker, Mindi; Emmell, Eva; Mikkelsen, S Rochelle; Burleson, Gary R; Burleson, Florence G; Volk, Amy; Weinstock, Daniel

    2015-01-01

    Murine gammaherpesvirus-68 (MHV-68), a natural pathogen of mice, is being evaluated as a model of Epstein Barr Virus (EBV) infection for use in investigation of the effects of immunomodulatory therapy on herpesvirus pathogenesis in humans. Immunosuppressive agents are used for treatment of a variety of autoimmune diseases as well as for prevention of tissue rejection after organ transplantation and can result in recrudescence of latent herpesvirus infections. Prior to examination of MHV-68 as a suitable model for EBV, better characterization of the MHV-68 model was desirable. Characterization of the MHV-68 model involved development of assays for detecting virus and for demonstration of safety when present in murine colonies. Limited information is available in the literature regarding MHV-68 transmission, although recent reports indicate the virus is not horizontally spread in research facilities. To further determine transmission potential, immunocompetent and immunodeficient mice were infected with MHV-68 and co-habitated with naïve animals. Molecular pathology assays were developed to characterize the MHV-68 model and to determine viral transmission. Horizontal transmission of virus was not observed from infected animals to naïve cagemates after fluorescence microscopy assays and quantitative PCR (qPCR). Serologic analysis complemented these studies and was used as a method of monitoring infection amongst murine colonies. Overall, these findings demonstrate that MHV-68 infection can be controlled and monitored in murine research facilities, and the potential for unintentional infection is low.

  5. Horizontal

    Institute of Scientific and Technical Information of China (English)

    ZHONG; Chunping

    2005-01-01

    [1]Wu, H., Bochner technique in differential geometry, Advance in Math. (in Chinese), 1981, 10(1): 57-76.[2]Morrow, J., Kodaira, K., Complex Manifolds, New York: Holt, Rinehart & Winston, 1971.[3]Abate, M., Aikou, T., Patrizio, G., Preface for Complex Finsler Geometry, Cont. Math., Vol. 196, Providence,RI: Amer. Math. Soc., 1996, 97-100.[4]Abate, M., Patrizio, G., Finsler Metrics-A global approach with applications to geometric function theory,Lecture Notes in Mathematics, Vol. 1591, Bedin: Springer-Verlag, 1994.[5]Antonelli, P. L., Lackey, B.(eds.), The Theory of Finslerian Laplacians and Applications, MAIA 459, Dordrecht:Kluwer Academic Publishers, 1998.[6]Bao, D., Lackey, B., A Hodge decomposition theorem for Finsler spaces, C. R. Acad. Sci. Paris, t. 323, Serie 1,1996, 51-56.[7]Munteanu, O., Weitzenbock formulas for horizontal and vertical Laplacians, Houston Journal of Mathematics,2003, 29(4): 889-900.[8]Faran, J. J., The equivalence problem for complex Finsler Hamiltonians, Cont. Math.,Vol. 196, Providence, RI:Amer. Math. Soc., 1996, 133-144.[9]Kobayashi, S., Complex Finsler vector bundles, Cont. Math., Vol. 196, Providence, RI: Amer. Math. Soc.,1996,145-153.[10]Aikou, T., On complex Finsler manifolds, Rep. Fac. Sci. Kagoshima Univ. (Math. Phys. & Chem.), 1991, 24:9-25.

  6. Antimicrobial susceptibility of Neisseria gonorrhoeae isolates from patients attending a public referral center for sexually transmitted diseases in Belo Horizonte, State of Minas Gerais, Brazil

    Directory of Open Access Journals (Sweden)

    Ligia Maria Bedeschi Costa

    2013-06-01

    Full Text Available Introduction The aim of this study was to determine the antimicrobial susceptibility of Neisseria gonorrhoeae isolates obtained from patients attending a public referral center for sexually transmitted diseases and specialized care services (STD/SCS in Belo Horizonte, Brazil. Methods Between March 2011 and February 2012, 201 specimens of Neisseria gonorrhoeae were consecutively obtained from men with symptoms of urethritis and women with symptons of cervicitis or were obtained during their initial consultation. The strains were tested using the disk diffusion method, and the minimum inhibitory concentrations of azithromycin, cefixime, ceftriaxone, ciprofloxacin, chloramphenicol, penicillin, tetracycline and spectinomycin were determined using the E-test. Results The specimens were 100% sensitive to cefixime, ceftriaxone and spectinomycin and exhibited resistances of 4.5% (9/201, 21.4% (43/201, 11.9% (24/201, 22.4% (45/201 and 32.3% (65/201 to azithromycin, ciprofloxacin, chloramphenicol, penicillin and tetracycline, respectively. Intermediate sensitivities of 17.9% (36/201, 4% (8/201, 16.9% (34/201, 71.1% (143/201 and 22.9% (46/201 were observed for azithromycin, ciprofloxacin, chloramphenicol, penicillin and tetracycline, respectively. The specimens had plasmid-mediated resistance to penicillin PPNG 14.5% (29/201 and tetracycline TRNG 11.5% (23/201. Conclusions The high percentage of detected resistance to penicillin, tetracycline, chloramphenicol and ciprofloxacin indicates that these antibiotics are not appropriate for gonorrhea treatment at the Health Clinic and possibly in Belo Horizonte. The resistance and intermediate sensitivity of these isolates indicates that caution is recommended in the use of azithromycin and emphasizes the need to establish mechanisms for the surveillance of antimicrobial resistance for the effective control of gonorrhea.

  7. Numerical Simulations of HH 555

    CERN Document Server

    Kajdic, Primoz

    2007-01-01

    We present 3D gasdynamic simulations of the Herbig Haro object HH 555. HH 555 is a bipolar jet emerging from the tip of an elephant trunk entering the Pelican Nebula from the adjacent molecular cloud. Both beams of HH 555 are curved away from the center of the H II region. This indicates that they are being deflected by a side-wind probably coming from a star located inside the nebula or by the expansion of the nebula itself. HH 555 is most likely an irradiated jet emerging from a highly embedded protostar, which has not yet been detected. In our simulations we vary the incident photon flux, which in one of our models is equal to the flux coming from a star 1 pc away emitting 5x10^48 ionizing (i. e., with energies above the H Lyman limit) photons per second. An external, plane-parallel flow (a ``side-wind'') is coming from the same direction as the photoionizing flux. We have made four simulations, decreasing the photon flux by a factor of 10 in each simulation. We discuss the properties of the flow and we co...

  8. Ammonia downstream from HH 80 North

    Science.gov (United States)

    Girart, Jose M.; Rodriguez, Luis F.; Anglada, Guillem; Estalella, Robert; Torrelles, Jose, M.; Marti, Josep; Pena, Miriam; Ayala, Sandra; Curiel, Salvador; Noriega-Crespo, Alberto

    1994-01-01

    HH 80-81 are two optically visible Herbig-Haro (HH) objects located about 5 minutes south of their exciting source IRAS 18162-2048. Displaced symmetrically to the north of this luminous IRAS source, a possible HH counterpart was recently detected as a radio continuum source with the very large array (VLA). This radio source, HH 80 North, has been proposed to be a member of the Herbig-Haro class since its centimeter flux density, angular size, spectral index, and morphology are all similar to those of HH 80. However, no object has been detected at optical wavelengths at the position of HH 80 North, possibly because of high extinction, and the confirmation of the radio continuum source as an HH object has not been possible. In the prototypical Herbig-Haro objects HH 1 and 2, ammonia emission has been detected downstream of the flow in both objects. This detection has been intepreted as a result of an enhancement in the ammonia emission produced by the radiation field of the shock associated with the HH object. In this Letter we report the detection of the (1,1) and (2,2) inversion transitions of ammonia downstream HH 80 North. This detection gives strong suppport to the interpretation of HH 80 North as a heavily obscured HH object. In addition, we suggest that ammonia emission may be a tracer of embedded Herbig-Haro objects in other regions of star formation. A 60 micrometer IRAS source could be associated with HH 80 North and with the ammonia condensation. A tentative explanation for the far-infrared emission as arising in dust heated by their optical and UV radiation of the HH object is presented.

  9. A Jet Model of HH Objects

    Science.gov (United States)

    Tenorio-Tagle, Guillermo; Rozyczka, Michal; Cantó, Jorge

    It is shown by means of two dimensional hydrodynamical simulations that Canto's model of HH objects does not lead to an entirely stationary flow. It causes both a stationary cylindrical shock (at the interaction place) and a fast moving region emitting an HH spectra. A coherent picture of these phenomena is here presented. The models account for "optical jet" structures embedded in a much larger (>0.1 pc) hydrodynamical jet at the tip of which an HH object should be found.

  10. Assessment of Snow Status Changes Using L-HH Temporal-Coherence Components at Mt. Dagu, China

    Directory of Open Access Journals (Sweden)

    Yong Wang

    2015-09-01

    Full Text Available Multitemporal Phased Array type L-band Synthetic Aperture Radar (PALSAR horizontally transmitted and horizontally received (HH coherence data was decomposed into temporal-coherence, spatial-coherence, and thermal noise components. The multitemporal data spanned between February and May of 2008, and consisted of two pairs of interferometric SAR (InSAR images formed by consecutive repeat passes. With the analysis of ancillary data, a snow increase process and a snow decrease process were determined. Then, the multiple temporal-coherence components were used to study the variation of thawing and freezing statuses of snow because the components can mostly reflect the temporal change of the snow that occurred between two data acquisitions. Compared with snow mapping results derived from optical images, the outcomes from the snow increase process and the snow decrease process reached an overall accuracy of 71.3% and 79.5%, respectively. Being capable of delineating not only the areas with or without snow cover but also status changes among no-snow, wet snow, and dry snow, we have developed a critical means to assess the water resource in alpine areas.

  11. Partner manipulation stabilises a horizontally transmitted mutualism.

    Science.gov (United States)

    Heil, Martin; Barajas-Barron, Alejandro; Orona-Tamayo, Domancar; Wielsch, Natalie; Svatos, Ales

    2014-02-01

    Mutualisms require protection from non-reciprocating exploiters. Pseudomyrmex workers that engage in an obligate defensive mutualism with Acacia hosts feed exclusively on the sucrose-free extrafloral nectar (EFN) that is secreted by their hosts, a behaviour linking ant energy supply directly to host performance and thus favouring reciprocating behaviour. We tested the hypothesis that Acacia hosts manipulate this digestive specialisation of their ant mutualists. Invertase (sucrose hydrolytic) activity in the ant midguts was inhibited by chitinase, a dominant EFN protein. The inhibition occurred quickly in cell-free gut liquids and in native gels and thus likely results from an enzyme-enzyme interaction. Once a freshly eclosed worker ingests EFN as the first diet available, her invertase becomes inhibited and she, thus, continues feeding on host-derived EFN. Partner manipulation acts at the phenotypic level and means that one partner actively controls the phenotype of the other partner to enhance its dependency on host-derived rewards.

  12. H-H interactions in Pd

    DEFF Research Database (Denmark)

    Christensen, O. B.; Ditlevsen, Peter; Jacobsen, Karsten Wedel;

    1989-01-01

    A discussion of the H-H interactions in a metal is given. Based on self-consistent total-energy calculations within the local-density approximation for H2 in a homogeneous electron gas, we show that metallic electrons make the H-H interaction more repulsive than in vacuum. Using effective...... of the calculated energetics, the thermodynamical properties of various palladium hydrides are modeled....

  13. NEW VARIABLE JET MODELS FOR HH 34

    Energy Technology Data Exchange (ETDEWEB)

    Raga, A. C.; Rodriguez-Gonzalez, A.; Esquivel, A. [Instituto de Ciencias Nucleares, Universidad Nacional Autonoma de Mexico, Ap. 70-543, 04510 Mexico, D.F. (Mexico); Noriega-Crespo, A. [Spitzer Science Center, California Institute of Technology, CA 91125 (United States)

    2012-01-15

    We consider newly derived proper motions of the HH 34 jet to reconstruct the evolution of this outflow. We first extrapolate ballistic trajectories for the knots (starting from their present-day positions and velocities) and find that at {approx}1000 yr in the future most of them will merge to form a larger-mass structure. This mass structure will be formed close to the present-day position of the HH 34S bow shock. We then carry out a fit to the ejection velocity versus time reconstructed from the observed proper motions (assuming that the past motion of the knots was ballistic) and use this fit to compute axisymmetric jet simulations. We find that the intensity maps predicted from these simulations do indeed match reasonably well the [S II] structure of HH 34 observed in Hubble Space Telescope images.

  14. Luminosity Targets for FCC-hh

    CERN Document Server

    Zimmermann, F.; Buffat, X.; Schulte, D.

    2016-01-01

    We discuss the choice of target values for the peak and integrated luminosity of a future high-energy frontier circular hadron collider (FCC-hh). We review the arguments on the physics reach of a hadron collider. Next we show that accelerator constraints will limit the beam current and the turnaround time. Taking these limits into account, we derive an expression for the ultimate integrated luminosity per year, depending on a possible pile-up limit imposed by the physics experiments. We finally benchmark our result against the planned two phases of FCC-hh [1, 2, 3

  15. X-rays from HH 80, HH 81, and the Central Region

    CERN Document Server

    Pravdo, S H; Maeda, Y; Pravdo, Steven H.; Tsuboi, Yohko; Maeda, Yoshitomo

    2004-01-01

    We report detections of X-rays from HH 80 and HH 81 with the ACIS instrument on the Chandra X-ray Observatory. These are among the most luminous HH sources in the optical and they are now the most luminous known in X-rays. These X-rays arise from the strong shocks that occur when the southern extension of this bipolar outflow slams into the ambient material. There is a one-to-one correspondence between regions of high X-ray emission and high H? emission. The X-ray luminosities of HH 80 and HH 81 are 4.5 and 4.3 x 1031 erg s-1, respectively, assuming the measured low-energy absorption is not in the sources. The measured temperature of the HH plasma is not as large as that expected from the maximum velocities seen in the extended tails of the optical emission lines. Rather it is consistent with the ~106 K temperature of the ?narrow? core of the optical lines. There is no observed emission from HH 80 North, the northern extension of the bipolar flow, based upon a measurement of lower sensitivity. We imaged the c...

  16. Gemini-IFU Spectroscopy of HH 111

    Science.gov (United States)

    Cerqueira, A. H.; Vasconcelos, M. J.; Raga, A. C.; Feitosa, J.; Plana, H.

    2015-03-01

    We present new optical observations of the Herbig-Haro (HH) 111 jet using the Gemini Multi Object Spectrograph in its Integral Field Unit mode. Eight fields of 5\\prime\\prime × 3\\buildrel{\\prime\\prime}\\over{.} 5 have been positioned along and across the HH 111 jet, covering the spatial region from knot E to L in HH 111 (namely, knots E, F, G, H, J, K, and L). We present images and velocity channel maps for the [O i] 6300+6360, Hα, [N ii] 6548+6583, and [S ii] 6716+6730 lines, as well as for the [S ii] 6716/6730 line ratio. We find that the HH 111 jet has an inner region with lower excitation and higher radial velocity, surrounded by a broader region of higher excitation and lower radial velocity. Also, we find higher electron densities at lower radial velocities. These results imply that the HH 111 jet has a fast, axial region with lower velocity shocks surrounded by a lower velocity sheath with higher velocity shocks. Based on observations obtained at the Gemini Observatory, which is operated by the Association of Universities for Research in Astronomy, Inc., under a cooperative agreement with the NSF on behalf of the Gemini partnership: the National Science Foundation (United States), the Science and Technology Facilities Council (United Kingdom), the National Research Council (Canada), CONICYT (Chile), the Australian Research Council (Australia), Ministério da Ciência, Tecnologia e Inovação (Brazil), and Ministerio de Ciencia, Tecnología e Innovación Productiva (Argentina).

  17. Ihog and Boi elicit Hh signaling via Ptc but do not aid Ptc in sequestering the Hh ligand.

    Science.gov (United States)

    Camp, Darius; Haitian He, Billy; Li, Sally; Althaus, Irene W; Holtz, Alexander M; Allen, Benjamin L; Charron, Frédéric; van Meyel, Donald J

    2014-10-01

    Hedgehog (Hh) proteins are secreted molecules essential for tissue development in vertebrates and invertebrates. Hh reception via the 12-pass transmembrane protein Patched (Ptc) elicits intracellular signaling through Smoothened (Smo). Hh binding to Ptc is also proposed to sequester the ligand, limiting its spatial range of activity. In Drosophila, Interference hedgehog (Ihog) and Brother of ihog (Boi) are two conserved and redundant transmembrane proteins that are essential for Hh pathway activation. How Ihog and Boi activate signaling in response to Hh remains unknown; each can bind both Hh and Ptc and so it has been proposed that they are essential for both Hh reception and sequestration. Using genetic epistasis we established here that Ihog and Boi, and their orthologs in mice, act upstream or at the level of Ptc to allow Hh signal transduction. In the Drosophila developing wing model we found that it is through Hh pathway activation that Ihog and Boi maintain the boundary between the anterior and posterior compartments. We dissociated the contributions of Ptc from those of Ihog/Boi and, surprisingly, found that cells expressing Ptc can retain and sequester the Hh ligand without Ihog and Boi, but that Ihog and Boi cannot do so without Ptc. Together, these results reinforce the central role for Ptc in Hh binding in vivo and demonstrate that, although Ihog and Boi are dispensable for Hh sequestration, they are essential for pathway activation because they allow Hh to inhibit Ptc and thereby relieve its repression of Smo.

  18. IR diagnostics of embedded jets: velocity resolved observations of the HH34 and HH1 jets

    CERN Document Server

    Lopez, R Garcia; Giannini, T; Eislöffel, J; Bacciotti, F; Podio, L

    2008-01-01

    We present VLT-ISAAC medium resolution spectroscopy of the HH34 and HH1 jets. Our aim is to derive the kinematics and the physical parameters and to study how they vary with jet velocity. We use several important diagnostic lines such as [FeII] 1.644um, 1.600um and H2 2.122um. In the inner jet region of HH34 we find that both the atomic and molecular gas present two components at high and low velocity. The [FeII] LVC in HH34 is detected up to large distances from the source (>1000 AU), at variance with TTauri jets. In H2 2.122um, the LVC and HVC are spatially separated. We detect, for the first time, the fainter red-shifted counterpart down to the central source. In HH1, we trace the jet down to ~1" from the VLA1 driving source: the kinematics of this inner region is again characterised by the presence of two velocity components, one blue-shifted and one red-shifted with respect to the source LSR velocity. In the inner HH34 jet region, ne increases with decreasing velocity. Up to ~10" from the driving source,...

  19. Accretion and ejection properties of embedded protostars: the case of HH26, HH34 and HH46 IRS

    CERN Document Server

    Antoniucci, S; Giannini, T; Lorenzetti, D

    2007-01-01

    We present the results of a near-IR spectroscopic analysis on 3 young embedded sources (HH26IRS, HH34IRS and HH46IRS) belonging to different star-forming regions and displaying well developed jet structures. The aim is to investigate the source accretion and ejection properties and their connection. We used VLT-ISAAC spectra (R~9000, H and K bands) to derive in a self-consistent way parameters like the star luminosity, the accretion luminosity and the mass accretion rate. Mass loss rates have also been estimated from the analysis of different emission features. The spectra present several emission lines but no photospheric features in absorption, indicating a large veiling in H and K. We detected features commonly observed in jet-driving sources (HI,[FeII],H_2,CO) and also a number of emission lines due to permitted atomic transitions, like NaI and TiI. The NaI 2.2um doublet is observed along with CO(2-0) band-head emission, indicating a common origin in an inner gaseous disc heated by accretion. We find that...

  20. Proper motions of the HH 1 jet

    Science.gov (United States)

    Raga, A. C.; Reipurth, B.; Esquivel, A.; Castellanos-Ramírez, A.; Velázquez, P. F.; Hernández-Martínez, L.; Rodríguez-González, A.; Rechy-García, J. S.; Estrella-Trujillo, D.; Bally, J.; González-Gómez, D.; Riera, A.

    2017-10-01

    We describe a new method for determining proper motions of extended objects, and a pipeline developed for the application of this method. We then apply this method to an analysis of four epochs of [S II] HST images of the HH 1 jet (covering a period of ≈20 yr). We determine the proper motions of the knots along the jet, and make a reconstruction of the past ejection velocity time-variability (assuming ballistic knot motions). This reconstruction shows an "acceleration" of the ejection velocities of the jet knots, with higher velocities at more recent times. This acceleration will result in an eventual merging of the knots in ≈450 yr and at a distance of ≈80'' from the outflow source, close to the present-day position of HH 1.

  1. Study of HH production at CMS

    CERN Document Server

    Francois, Brieuc Arnaud L

    2016-01-01

    The production of a pair of Higgs bosons provides a direct handle on the structure of the Higgs field potential. While the HH production within the SM is very small and essentially out of the experimental reach within the LHC Run I or II, several beyond SM theories foresee an enhancement that can be already probed with the available data. First searches for resonant and non-resonant Higgs pair production made using CMS Run II data will be presented.

  2. Infrasound Generation from the HH Seismic Hammer.

    Energy Technology Data Exchange (ETDEWEB)

    Jones, Kyle Richard

    2014-10-01

    The HH Seismic hammer is a large, "weight-drop" source for active source seismic experiments. This system provides a repetitive source that can be stacked for subsurface imaging and exploration studies. Although the seismic hammer was designed for seismological studies it was surmised that it might produce energy in the infrasonic frequency range due to the ground motion generated by the 13 metric ton drop mass. This study demonstrates that the seismic hammer generates a consistent acoustic source that could be used for in-situ sensor characterization, array evaluation and surface-air coupling studies for source characterization.

  3. Infrasound Generation from the HH Seismic Hammer.

    Energy Technology Data Exchange (ETDEWEB)

    Jones, Kyle Richard

    2014-10-01

    The HH Seismic hammer is a large, "weight-drop" source for active source seismic experiments. This system provides a repetitive source that can be stacked for subsurface imaging and exploration studies. Although the seismic hammer was designed for seismological studies it was surmised that it might produce energy in the infrasonic frequency range due to the ground motion generated by the 13 metric ton drop mass. This study demonstrates that the seismic hammer generates a consistent acoustic source that could be used for in-situ sensor characterization, array evaluation and surface-air coupling studies for source characterization.

  4. Fabry-Perot Observations of HH 1/2

    Directory of Open Access Journals (Sweden)

    A. Riera

    2005-01-01

    Full Text Available Presentamos nuevas observaciones Fabry-Perot del sistema HH1/2 en la l nea de H. Se han obtenidos los perfiles de las l neas, y los mapas de velocidad radial y de dispersi n de velocidades a partir de los canales de velocidad de los objetos HH 1 y HH 2. La distribuci on espacial de la velocidad radial de ambos objetos (HH 1, HH 2 presenta material desplazado al rojo hacia la fuente, y material desplazado al azul alej ndose de la fuente. Un modelo que contempla la presencia de emisi n directa+dispersada con tres condensaciones emisoras reproduce cualitativamente la distribuci n espacial de la velocidad radial y de la dispersi n de velocidades de HH 2.

  5. Multiepoch Radio Observations of the Exciting Sources of HH 212 and HH 119

    Directory of Open Access Journals (Sweden)

    R. Galván Madrid

    2004-01-01

    Full Text Available Presentamos observaciones de alta resolución angular (- 0.``3 hechas con el Very Large Array a 3.5 cm hacia las regiones de las fuentes excitadoras de dos sistemas Herbig-Haro: HH 212 en Orión y HH 119 en B335. Las observaciones fueron hechas durante tres épocas diferentes con el objetivo de medir posibles variaciones temporales rápidas (en la escala de una semana a un mes en las fuentes. En HH 212 detectamos, promediando las observaciones de las tres épocas, una fuente muy débil justo en la posición esperada para la fuente excitadora del sistema HH. La comparación con otras observaciones de radio de esta fuente indica variación temporal considerable en escala de años. En B335 detectamos en cada época al objeto previamente reportado por otros autores y nuestros resultados sugieren que esta fuente, un chorro térmico de radio, es variable en escalas de tiempo de un mes. Discutimos posibles explicaciones para esta rápida variabilidad.

  6. Diffuse ionizing radiation within HH jets

    Energy Technology Data Exchange (ETDEWEB)

    Esquivel, A.; Raga, A. C., E-mail: esquivel@nucleares.unam.mx, E-mail: raga@nucleares.unam.mx [Instituto de Ciencias Nucleares, Universidad Nacional Autónoma de México, Apartado Postal 70-543, 04510 Mexico D.F. (Mexico)

    2013-12-20

    We present numerical hydrodynamical simulations of a time-dependent ejection velocity precessing jet. The parameters used in our models correspond to a high excitation Herbig-Haro object, such as HH 80/81. We have included the transfer of ionizing radiation produced within the shocked regions of the jet. The radiative transfer is computed with a ray-tracing scheme from all the cells with an emissivity above a certain threshold. We show the development of a radiative precursor, and compare the morphology with a model without the diffuse radiation. Our simulations show that the morphology of the Hα emission is affected considerably if the diffuse ionizing radiation is accounted for. The predicted Hα position-velocity diagram (i.e., spatially resolved emission line profiles) from a model with the transfer of ionizing radiation has a relatively strong component at zero velocity, corresponding to the radiative precursor. Qualitatively similar 'zero velocity components' are observed in HH 80/81 and in the jet from Sanduleak's star in the Large Magellanic Cloud.

  7. Horizontal Accelerator

    Data.gov (United States)

    Federal Laboratory Consortium — The Horizontal Accelerator (HA) Facility is a versatile research tool available for use on projects requiring simulation of the crash environment. The HA Facility is...

  8. HH-65A Dolphin digital integrated avionics

    Science.gov (United States)

    Huntoon, R. B.

    1984-01-01

    Communication, navigation, flight control, and search sensor management are avionics functions which constitute every Search and Rescue (SAR) operation. Routine cockpit duties monopolize crew attention during SAR operations and thus impair crew effectiveness. The United States Coast Guard challenged industry to build an avionics system that automates routine tasks and frees the crew to focus on the mission tasks. The HH-64A SAR avionics systems of communication, navigation, search sensors, and flight control have existed independently. On the SRR helicopter, the flight management system (FMS) was introduced. H coordinates or integrates these functions. The pilot interacts with the FMS rather than the individual subsystems, using simple, straightforward procedures to address distinct mission tasks and the flight management system, in turn, orchestrates integrated system response.

  9. Integral Field Spectroscopy of HH 262: The Spectral Atlas

    CERN Document Server

    López, R; Sánchez, S F; Gómez, G; Estalella, R; Riera, A

    2008-01-01

    HH 262 is a group of emitting knots displaying an "hour-glass" morphology in the Halpha and [SII] lines, located 3.5' to the northeast of the young stellar object L1551-IRS5, in Taurus. We present new results of the kinematics and physical conditions of HH 262 based on Integral Field Spectroscopy covering a field of 1.5'x3', which includes all the bright knots in HH 262. These data show complex kinematics and significant variations in physical conditions over the mapped region of HH 262 on a spatial scale of <3". A new result derived from the IFS data is the weakness of the [NII] emission (below detection limit in most of the mapped region of HH 262), including the brightest central knots. Our data reinforce the association of HH 262 with the redshifted lobe of the evolved molecular outflow L1551-IRS5. The interaction of this outflow with a younger one, powered by L1551 NE, around the position of HH 262 could give rise to the complex morphology and kinematics of HH 262.

  10. A 3-mode, Variable Velocity Jet Model for HH 34

    Science.gov (United States)

    Raga, A.; Noriega-Crespo, A.

    1998-01-01

    Variable ejection velocity jet models can qualitatively explain the appearance of successive working surfaces in Herbig-Haro (HH) jets. This paper presents an attempt to explore which features of the HH 34 jet can indeed be reproduced by such a model.

  11. The IFIN-HH triple coincidence liquid scintillation counter

    CSIR Research Space (South Africa)

    Razdolescu, AC

    2006-10-01

    Full Text Available at IFIN-HH using a 3 H standard. The performances of the IFIN-HH TDCR counter was checked against the measurement results of the TDCR counters of CSIR NML (South Africa), RC (Poland) and LNHB (France). A set of ready-to-measure Ni-63 sources in liquid...

  12. Salivary IgA against sporozoite-specific embryogenesis-related protein (TgERP) in the study of horizontally transmitted toxoplasmosis via T. gondii oocysts in endemic settings.

    Science.gov (United States)

    Mangiavacchi, B M; Vieira, F P; Bahia-Oliveira, L M G; Hill, D

    2016-09-01

    The aim of this study was to contribute to the better understanding of the relative epidemiological importance of different modes of infection with respect to horizontal transmission of Toxoplasma gondii in endemic settings. We investigated the prevalence of salivary IgA against a sporozoite-specific embryogenesis-related protein (TgERP) in a highly endemic area for toxoplasmosis in Brazil in order to pinpoint parasite transmission via oocysts. Prevalence calculated by salivary IgA specific to TgERP was compared to the prevalence calculated by serum IgG against both TgERP and tachyzoites (in conventional serological tests). Prevalence calculated by different serological and salivary parameters varied in the studied age groups. However, for the 15-21 years age group, values for T. gondii prevalence estimated by conventional serological tests and by anti-TgERP salivary IgA were similar; i.e. 68·7% and 66·6% or 66·7%, respectively, using two different cut-off parameters for salivary IgA anti-TgERP. Furthermore, salivary IgA anti-TgERP for this age group presented the highest specificity (93·33%), sensitivity (93·94%), and likelihood (14·09) compared to all the other age groups. These data demonstrate the importance of age for salivary IgA investigation against TgERP to estimate the mode of T. gondii transmission in endemic settings.

  13. IFIN - HH contribution at the Pierre Auger observatory

    Science.gov (United States)

    Brancus, I. M.; Saftoiu, A.

    2017-06-01

    Since 2000, in collaboration with KIT, Germany, the research of Astroparticle Physics has developed in IFIN-HH Bucharest. Romanian researchers participated in large international experiments, KASCADE Grande and LOPES, for investigating cosmic rays. New experimental devices have been built in IFIN-HH Bucharest for measuring the cosmic ray muons. Based on the experience and results gained over that time, Romanian researchers became part of the Pierre Auger Collaboration, the largest complex experiment for the investigation of Extensive Air Showers. The contribution of IFIN-HH is focused on the studies of cosmic rays using radio antennae and the measuring of cosmic muons using detectors based on new technology.

  14. 2D Spectroscopy of HH588 Large-Scale Outflow

    Science.gov (United States)

    Hovhannissian, Elena R.; Ogura, K.; Movsessian, Tigran A.; Magakian, Tigran Yu.; Nikogossian, Elena H.

    2007-08-01

    The HH588 flow is studied with multi-pupil spectrograph on the 2.6 m telescope of Byurakan observatory. The bright components of this flow are analyzed, using the maps of emission lines and radial velocities. The bipolar nature of this outflow is obvious from their radial velocities. The unusual feature of HH588 flow is its inclusion in the bright-rimmed cloud; thus, it can belong to so-called irradiated jets. It is worth to mention that all HH-objects studied here show a deceleration in the regions of interaction with the interstellar medium.

  15. X-rays from HH210 in the Orion nebula

    CERN Document Server

    Grosso, N; Getman, K V; Kästner, J H; Bally, J; McCaughrean, M J; Grosso, Nicolas; Feigelson, Eric D.; Getman, Konstantin V.; Kastner, Joel H.; Bally, John; Caughrean, Mark J. Mc

    2006-01-01

    We report the detection during the Chandra Orion Ultradeep Project (COUP) of two soft, constant, and faint X-ray sources associated with the Herbig-Haro object HH210. HH210 is located at the tip of the NNE finger of the emission line system bursting out of the BN-KL complex, northwest of the Trapezium cluster in the OMC-1 molecular cloud. Using a recent Halpha image obtained with the ACS imager on board HST, and taking into account the known proper motions of HH210 emission knots, we show that the position of the brightest X-ray source, COUP703, coincides with the emission knot 154-040a of HH210, which is the emission knot of HH210 having the highest tangential velocity (425 km/s). The second X-ray source, COUP704, is located on the complicated emission tail of HH210 close to an emission line filament and has no obvious optical/infrared counterpart. Spectral fitting indicates for both sources a plasma temperature of ~0.8 MK and absorption-corrected X-ray luminosities of about 1E30 erg/s (0.5-2.0 keV). These X...

  16. Optical imaging of L723: the structure of HH 223

    CERN Document Server

    López, R; Gómez, G; Riera, A

    2006-01-01

    We imaged the Lynds 723 dark nebula (L723) with the aim of studying the morphology of the Herbig-Haro object HH 223 and other line-emission nebula detected in the region. We obtained deep narrow-band images in the Halpha and [SII] lines and in the continuum nearby Halpha of a field of ~5' of the L723 dark nebula centered on HH 223. The Halpha and [SII] images reveal the detailed morphology of HH 223, unresolved in previous optical images. Both images show a quite complex knotty, wiggling structure embedded in a low-emission nebula. Comparison between the [SII] and Halpha fluxes of the knots are indicative of variations in the excitation conditions through HH 223. In addition, several other faint nebula are detected in Halpha a few arcmin to the SE and to the NW of HH 223, all of them lying projected onto the east-west pair of lobes of the quadrupolar CO outflow. Comparison between the Halpha and the continuum images confirms the HH-like nature of the Vrba object V83, while the Vrba objects V84 and V85 are ide...

  17. Solidification microstructure formation in HK40 and HH40 alloys

    Science.gov (United States)

    Ding, Xian-fei; Liu, Dong-fang; Guo, Pei-liang; Zheng, Yun-rong; Feng, Qiang

    2016-04-01

    The microstructure formation processes in HK40 and HH40 alloys were investigated through JmatPro calculations and quenching performed during directional solidification. The phase transition routes of HK40 and HH40 alloys were determined as L → L + γ → L + γ + M7C3 → γ + M7C3 → γ + M7C3 + M23C6→ γ + M23C6 and L → L + δ → L + δ + γ→ L + δ + γ + M23C6 δ + γ + M23C6, respectively. The solidification mode was determined to be the austenitic mode (A mode) in HK40 alloy and the ferritic-austenitic solidification mode (FA mode) in HH40 alloy. In HK40 alloy, eutectic carbides directly precipitate in a liquid and coarsen during cooling. The primary γ dendrites grow at the 60° angle to each other. On the other hand, in HH40 alloy, residual δ forms because of the incomplete transformation from δ to γ. Cr23C6 carbide is produced in solid delta ferrite δ but not directly in liquid HH40 alloy. Because of carbide formation in the solid phase and no rapid growth of the dendrite in a non-preferential direction, HH40 alloy is more resistant to cast defect formation than HK40 alloy.

  18. The precession of the HH 111 flow in the infrared

    CERN Document Server

    Noriega-Crespo, A; Lora, V; Stapelfeldt, K R; Carey, S J

    2011-01-01

    We present Spitzer IRAC images of the HH 111 outflow, that show a wealth of condensations/knots in both jet and counterjet. Studying the positional distribution of these knots, we find very suggestive evidence of a mirror symmetric pattern in the jet/counterjet flow. We model this pattern as the result of an orbital motion of the jet source around a binary companion. From a fit of an analytic, ballistic model to the observed path of the HH 111 system, we find that the motion in a binary with two approx. 1 Msolar stars (one of them being the HH 111 source), in a circular orbit with a separation of approx. 186 AU would produce the mirror symmetric pattern seen in the outflow.

  19. Structure and Biological Roles of Sinorhizobium fredii HH103 Exopolysaccharide

    Science.gov (United States)

    Acosta-Jurado, Sebastián; Soto, María J.; Margaret, Isabel; Crespo-Rivas, Juan C.; Sanjuan, Juan; Temprano, Francisco; Gil-Serrano, Antonio; Ruiz-Sainz, José E.; Vinardell, José M.

    2014-01-01

    Here we report that the structure of the Sinorhizobium fredii HH103 exopolysaccharide (EPS) is composed of glucose, galactose, glucuronic acid, pyruvic acid, in the ratios 5∶2∶2∶1 and is partially acetylated. A S. fredii HH103 exoA mutant (SVQ530), unable to produce EPS, not only forms nitrogen fixing nodules with soybean but also shows increased competitive capacity for nodule occupancy. Mutant SVQ530 is, however, less competitive to nodulate Vigna unguiculata. Biofilm formation was reduced in mutant SVQ530 but increased in an EPS overproducing mutant. Mutant SVQ530 was impaired in surface motility and showed higher osmosensitivity compared to its wild type strain in media containing 50 mM NaCl or 5% (w/v) sucrose. Neither S. fredii HH103 nor 41 other S. fredii strains were recognized by soybean lectin (SBL). S. fredii HH103 mutants affected in exopolysaccharides (EPS), lipopolysaccharides (LPS), cyclic glucans (CG) or capsular polysaccharides (KPS) were not significantly impaired in their soybean-root attachment capacity, suggesting that these surface polysaccharides might not be relevant in early attachment to soybean roots. These results also indicate that the molecular mechanisms involved in S. fredii attachment to soybean roots might be different to those operating in Bradyrhizobium japonicum. PMID:25521500

  20. FCC-hh Hadron Collider - Parameter Scenarios and Staging Options

    CERN Document Server

    Benedikt, Michael; Schulte, Daniel; Zimmermann, F; Syphers, M J

    2015-01-01

    FCC-hh is a proposed future energy-frontier hadron collider, based on dipole magnets with a field around 16 T installed in a new tunnel with a circumference of about 100 km, which would provide proton collisions at a centre-of-mass energy of 100 TeV, as well as heavy-ion collisions at the equivalent energy. The FCC-hh should deliver a high integrated proton-proton luminosity at the level of several 100 fb−1 per year, or more. The challenges for operating FCC-hh with high beam current and at high luminosity include the heat load from synchrotron radiation in a cold environment, the radiation from collision debris around the interaction region, and machine protection. In this paper, starting from the FCC-hh design baseline parameters we explore different approaches for increasing the integrated luminosity, and discuss the impact of key individual pa- rameters, such as the turnaround time. We also present some injector considerations and options for early hadron-collider operation.

  1. Horizontal gene transfer and bacterial diversity

    Indian Academy of Sciences (India)

    Chitra Dutta; Archana Pan

    2002-02-01

    Bacterial genomes are extremely dynamic and mosaic in nature. A substantial amount of genetic information is inserted into or deleted from such genomes through the process of horizontal transfer. Through the introduction of novel physiological traits from distantly related organisms, horizontal gene transfer often causes drastic changes in the ecological and pathogenic character of bacterial species and thereby promotes microbial diversification and speciation. This review discusses how the recent influx of complete chromosomal sequences of various microorganisms has allowed for a quantitative assessment of the scope, rate and impact of horizontally transmitted information on microbial evolution.

  2. Optical spectroscopy of HH-exciting stars from scattered light continua

    Science.gov (United States)

    Cohen, M.; Dopita, M. A.; Schwartz, R. D.

    1986-01-01

    Optical spectra of the reflected light continua visible in parts of several Herbig-Haro objects are presented. HH 100 unmistakably scatters the chromospheric spectrum of a strong emission-line T Tau star. HH 48S also reflects a T Tau stellar spectrum, as perhaps do HH 24 and HH 55, but less convincingly. HH 55 reveals photospheric absorption features too, corresponding to an M3.5 T Tau star. The continuum in HH 120 (= CG 30 HH) is unclassifiable while that in HH 46A has dimmed considerably (by a factor of order 20) although, only 7 yr ago, it clearly reflected a strong-line T Tau spectrum. It is concluded that at least some of the stars that excite Herbig-Haro nebulae, even when those stars are not directly visible, pass through a strong-line T Tau phase, and can undergo abrupt and dramatic changes in visual luminosity.

  3. Sexually transmitted diphtheria.

    Science.gov (United States)

    Berger, Anja; Lensing, Carmen; Konrad, Regina; Huber, Ingrid; Hogardt, Michael; Sing, Andreas

    2013-03-01

    Diphtheria is caused by diphtheria toxin-producing Corynebacterium species. While classical respiratory diphtheria is transmitted by droplets, cutaneous diphtheria often results from minor trauma. This report concerns the first case of sexually transmitted diphtheria in a patient with non-gonococcal urethritis after orogenital contact.

  4. First results for a FCC-hh ring optics design

    CERN Document Server

    Chance, Antoine; Payet, Jacques; Alemany Fernandez, Reyes; Holzer, Bernhard; Schulte, Daniel

    2015-01-01

    The first order considerations of the optics for the FCC-hh ring are presented. The arc cell is generated taking into account some general considerations like the whole circumference, maximum gradients and lengths of the elements in the cell. The integration of the insertion regions started. Three types of Dispersion Suppressors (DIS) are studied. The sensitivity of the arc parameters to these layout considerations is studied in more detail. An alternative layout is shown as well.

  5. MOS Mapping of the NIR Outflow HH 223

    Science.gov (United States)

    López, R.; Acosta-Pulido, J. A.; Estalella, R.; Gómez, G.; García-Lorenzo, B.

    2016-10-01

    The Multi-Object-Spectroscopy (MOS) mode of LIRIS was used to map the near-IR stellar outflow HH 223, in the dark cloud Lynds 723 (L723). HH 223 spatially coincides with the east-west component of the L723 quadrupolar CO outflow. The radio continuum source SMA2, towards the center of the quadrupolar CO outflow, hides the YSO that seems to power both the near-IR and the CO outflows. To map the S-shaped, near-IR emission of HH 223, extending ˜ 5', an appropriate mask was designed, with 16 rectangular slitlets. J, H and K-band spectra (R ˜eq 2500) were obtained through the mask. The kinematics of the neutral (H2) and ionized ([FeII]) gas outflow was derived from these data. The results confirm that both the near-IR and the CO outflows have a common driving source. To our knowledge, this is the first use of the MOS-LIRIS observing mode with the mask designed ad hoc to fit several extended, nonaligned targets.

  6. Interpreting the proper motions of the HH 34S bowshock

    Directory of Open Access Journals (Sweden)

    A. C. Raga

    2002-01-01

    Full Text Available Reipurth et al. (2002 han obtenido movimientos propios muy detallados del choque a proa HH 34S usando imágenes obtenidas con el Hubble Space Telescope (HST. Encontramos que estos movimientos propios pueden ser usados para reconstruir la velocidad de choque y la velocidad más allá de HH 34S en función de posición. De este ejercicio, obtenemos velocidades de choque en el intervalo de 60 a 120 km s1, lo cual concuerda con determinaciones previas basadas en el análisis de cocientes y perfiles de líneas de emisión. También deducimos la presencia de un flujo con velocidades de 200 km s1 más allá de HH 34S, el cual se extiende hasta 10 a cada lado del eje del sistema. Interpretamos este flujo como la estela dejada por eventos de eyección previos, y mostramos que una simulación numérica de una eyección con dependencia temporal logra reproducir las propiedades de este flujo en una forma convincente.

  7. Sexually transmitted infections

    African Journals Online (AJOL)

    AJRH Managing Editor

    treatment practices of sexually transmitted infections among brothel based female sex workers Three hundred and twenty three consenting ... five top diseases for which Nigerians seek medical ... in other countries have also revealed a high.

  8. Sexually Transmitted Diseases

    Science.gov (United States)

    Sexually transmitted diseases (STDs) are infections that are passed from one person to another through sexual contact. The causes of STDs ... often help with the symptoms and keep the disease under control. Correct usage of latex condoms greatly ...

  9. HH 1158: THE LOWEST LUMINOSITY EXTERNALLY IRRADIATED HERBIG–HARO JET

    Energy Technology Data Exchange (ETDEWEB)

    Riaz, B. [Max-Planck-Institut für Extraterrestrische Physik, Giessenbachstrasse 1, D-85748 Garching (Germany); Whelan, E. T. [Institute für Astronomie und Astrophysik, Eberhard Karls University Tuebingen, Sand 1, D-72076 Tübingen (Germany)

    2015-12-20

    We have identified a new externally irradiated Herbig–Haro (HH) jet, HH 1158, within ∼2 pc of the massive OB type stars in the σ Orionis cluster. At an L{sub bol} ∼ 0.1 L{sub ⊙}, HH 1158 is the lowest luminosity irradiated HH jet identified to date in any cluster. Results from the analysis of high-resolution optical spectra indicate asymmetries in the brightness, morphology, electron density, velocity, and the mass outflow rates for the blue and redshifted lobes. We constrain the position angle of the HH 1158 jet at 102° ± 5°. The mass outflow rate and the mean accretion rate for HH 1158 using multiple diagnostics are estimated to be (5.2 ± 2.6) × 10{sup −10} M{sub ⊙} yr{sup −1} and (3.0 ± 1.0) × 10{sup −10} M{sub ⊙} yr{sup −1}, respectively. The properties for HH 1158 are notably similar to the externally irradiated HH 444–HH 447 jets previously identified in σ Orionis. In particular, the morphology is such that the weaker jet beam is tilted toward the massive stars, indicating a higher extent of photo-evaporation. The high value for the Hα/[S ii] ratio is also consistent with the ratios measured in other irradiated jets, including HH 444–HH 447. The presence of an extended collimated jet that is bipolar and the evidence of shocked emission knots make HH 1158 the first unique case of irradiated HH jets at the very low-luminosity end, and provides an opportunity to learn the physical properties of very faint HH jet sources.

  10. Sexually transmitted infections.

    Science.gov (United States)

    Fuchs, Wolfgang; Brockmeyer, Norbert H

    2014-06-01

    In no other medical field former rare infections of the 1980(th) and 1990(th) occur again as this is seen in the field of venerology which is as well based on the mobility of the population. Increasing rates of infections in Europe, and increasing bacteriological resistances face health professionals with new challenges. The WHO estimates more than 340 million cases of illnesses worldwide every year. Diseases caused by sexually transmitted infections (STI) in a strict sense are syphilis, gonorrhea, lymphogranuloma venereum, granuloma inguinale, and chancroid. In a wider sense, all illnesses are included which can mainly be transmitted through sexual contact. The term "sexual contact" has to be seen widely, from close physical contact to all variants of sexual behavior. This CME article is an overview of the most common occurring sexually transmitted infections in clinical practice. Both, basic knowledge as well as recent developments are discussed below.

  11. Synchrotron radiation backgrounds for the FCC-hh experiments

    CERN Document Server

    Collamati, Francesco; Burkhardt, Helmut; Kersevan, Roberto

    2017-01-01

    In this paper we present a detailed analysis of the Synchrotron Radiation emitted by the 50 TeV protons of the FCC-hh in the last bending and quadrupole magnets upstream of the interaction region. We discuss the characteristics of this radiation in terms of power, flux, photon spectrum and fans with and without crossing angle for comparison. We mainly focus our study on the fraction of photons that may hit the detector, with a full tracking in GEANT4 that simulates the interaction within the central beam pipe.

  12. Beam-beam studies for FCC-hh

    CERN Document Server

    Barranco Garcia, Javier; Buffat, Xavier; Furuseth, Sondre Vik

    2017-01-01

    The Future Circular Collider hadron-hadron (FCC-hh) design study is currently exploring different IR design possibilities including round and flat optics or different crossing schemes. The present study intends to evaluate each scenario from the beam-beam effects point of view. In particular the single particle long term stability to maximize beam lifetimes and luminosity reach is used to quantify the differences. The impact of strong head on interactions on the beam quality and lifetime is addressed by means of GPU accelerated simulations code featuring a weak-strong 6-dimensional beam-beam interaction.

  13. An Extremely Bright Echo Associated With SN 2002hh

    CERN Document Server

    Welch, D L; Campbell, Amy; Barlow, M J; Sugerman, Ben E K; Meixner, Margaret; Bank, S H R

    2007-01-01

    We present new, very late-time optical photometry and spectroscopy of the interesting Type II-P supernova, SN 2002hh, in NGC 6946. Gemini/GMOS-N has been used to acquire visible spectra at six epochs between 2004 August and 2006 July, following the evolution of the SN from age 661 to 1358 days. Few optical spectra of Type II supernovae with ages greater than one year exist. In addition, g'r'i' images were acquired at all six epochs. The spectral and photometric evolution of SN 2002hh has been very unusual. Measures of the brightness of this SN, both in the R and I bands as well as in the H-alpha emission flux, show no significant fading over an interval of nearly two years. The most straightforward explanation for this behavior is that the light being measured comes not only from the SN itself but also from an echo off of nearby dust. Echoes have been detected previously around several SNe but these echoes, at their brightest, were ~8 mag below the maximum brightness of the SN. At V~21 mag, the putative echo ...

  14. Models for the Infrared Cavity of HH 46/47

    Science.gov (United States)

    Raga, A. C.; Noriega-Crespo, A.; Gonzalez, R. F.; Velazquez, P. F.

    2004-01-01

    We have modeled the limb-brightened cavity seen in the new Spitzer Space Telescope IR images of the southwest lobe of HH 46/47 as the bow shock driven by an outflow from a young, low-mass star. We present models in which the outflow is a perfectly collimated, straight jet, models in which the jet precesses, and finally a model in which the outflow takes the form of a latitude-dependent wind. We study cases in which the outflow moves into a constant-density cloud and into a stratified cloud. We find that the best agreement with the observed cavity is obtained for the precessing jet in a stratified cloud. However, the straight jet (traveling in a stratified cloud) also gives cavity shapes close to the observed one. The latitude-dependent wind model that we have computed gives cavity shapes that are substantially wider than the observed cavity. We therefore conclude that the cavity seen in the Spitzer observations of the southwest lobe of the HH 46/47 outflow do not seem to imply the presence of a latitude-dependent wind, as it can be modeled successfully with a perfectly collimated jet model.

  15. HH 1158: The lowest luminosity externally irradiated Herbig-Haro jet

    CERN Document Server

    Riaz, B

    2015-01-01

    We have identified a new externally irradiated Herbig-Haro (HH) jet, HH 1158, within ~2 pc of the massive OB type stars in the sigma Orionis cluster. At an Lbol ~ 0.1 Lsun, HH 1158 is the lowest luminosity irradiated HH jet identified to date in any cluster. Results from the analysis of high-resolution optical spectra indicate asymmetries in the brightness, morphology, electron density, velocity, and the mass outflow rates for the blue and red-shifted lobes. We constrain the position angle of the HH 1158 jet at 102+/-5 degree. The mass outflow rate and the mean accretion rate for HH 1158 using multiple diagnostics are estimated to be (5.2 +/- 2.6) x 10^(-10) Msun/yr and (3.0 +/- 1.0) x 10^(-10) Msun/yr, respectively. The properties for HH 1158 are notably similar to the externally irradiated HH 444 -- HH 447 jets previously identified in sigma Orionis. In particular, the morphology is such that the weaker jet beam is tilted towards the massive stars, indicating a higher extent of photo-evaporation. The high v...

  16. Spitzer spectral line mapping of the HH211 outflow

    DEFF Research Database (Denmark)

    Dionatos, Odyssefs; Nisini, Brunella; Cabrit, Sylvie;

    2010-01-01

    Aims: We employ archival Spitzer slit-scan observations of the HH211 outflow in order to investigate its warm gas content, assess the jet mass flux in the form of H2 and probe for the existence of an embedded atomic jet. Methods: Detected molecular and atomic lines are interpreted by means......-structure lines of S, Fe+, and Si+. H2 is detected down to 5" from the source and is characterized by a "cool" T~300K and a "warm" T~1000 K component, with an extinction Av ~ 8 mag. The amount of cool H2 towards the jet agrees with that estimated from CO assuming fully molecular gas. The warm component is well...

  17. $H^{+}H^{-}$ Pair Production at the Large Hadron Collider

    CERN Document Server

    Barrientos-Bendezu, A A

    2000-01-01

    We study the pair production of charged Higgs bosons at the CERN Large Hadron Collider in the context of the minimal supersymmetric extension of the standard model. We compare the contributions due to qq-bar annihilation at the tree level and gg fusion, which proceeds at one loop. At small or large values of tan(beta), H^+H^- production proceeds dominantly via bb-bar annihilation, due to Feynman diagrams involving neutral CP-even Higgs bosons and top quarks, which come in addition to the usually considered Drell-Yan diagrams. In the case of gg fusion, the squark loop contributions may considerably enhance the well-known quark loop contributions.

  18. HIGH ANGULAR RESOLUTION MULTI-LINE STUDY OF HH 1 AND 2

    Energy Technology Data Exchange (ETDEWEB)

    Raga, A. C.; Castellanos-Ramírez, A. [Instituto de Ciencias Nucleares, Universidad Nacional Autónoma de México, Ap. 70-543, 04510 D.F., México (Mexico); Reipurth, Bo; Chiang, Hsin-Fang [Institute for Astronomy, University of Hawaii at Manoa, Hilo, HI 96720 (United States); Bally, J., E-mail: raga@nucleares.unam.mx [Center for Astrophysics and Space Astronomy, University of Colorado, UCB 389, Boulder, CO 80309 (United States)

    2015-10-15

    We present new Hubble Space Telescope (HST) narrow band images of the bright Herbig–Haro (HH) objects HH 1 and 2 in the light of the Hα, Hβ, [O i] 6300, [O ii] 3726+28, [O iii] 5007 and [S ii] 6716+30 emission lines. The resulting emission and line ratio maps give an improved picture of the physical structure of these HH objects, showing the presence of spatially limited, high excitation/ionization ridges. We find that HH 1 has a morphology that could be interpreted in terms of a single, asymmetric bow shock, and that many of the clumps of HH 2 fall in two bow-shaped structures of different excitations. We also construct two-line ratio plots showing clear trends, which are much simpler than the highly complex spatial distributions of the emission, and are therefore interesting for testing shock models of HH objects (we only present a comparison with previously published, steady plane-parallel shock models). We have also used the temperature-sensitive [O i]/[S ii] line ratio to evaluate the temperature range and to obtain temperature maps of HH 1 and 2. We find that this line ratio picks out emitting regions with temperatures ≈10{sup 4} K, except along the leading edges of the HH 1 and 2 bow shocks (in which temperatures of ∼3 → 5 × 10{sup 4} K are obtained)

  19. The prevalence of anxiety and depression in patients with or without hyperhidrosis (HH).

    Science.gov (United States)

    Bahar, Rayeheh; Zhou, Pingyu; Liu, Yudan; Huang, Yuanshen; Phillips, Arlie; Lee, Tim K; Su, Mingwan; Yang, Sen; Kalia, Sunil; Zhang, Xuejun; Zhou, Youwen

    2016-12-01

    There are conflicting data about the correlation between hyperhidrosis (HH) and anxiety and depression. We sought to determine the prevalence of anxiety and depression in patients with or without HH. We examined 2017 consecutive dermatology outpatients from Vancouver, British Columbia, Canada, and Shanghai, China, using Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7 scales for anxiety and depression assessments. Multivariable logistic regression analysis was performed to evaluate if the impact of HH on anxiety and depression is dependent on demographic factors and diagnoses of the patients' presenting skin conditions. The prevalence of anxiety and depression was 21.3% and 27.2% in patients with HH, respectively, and 7.5% and 9.7% in patients without HH, respectively (P value anxiety and depression. Multivariable analysis showed that HH-associated increase in anxiety and depression prevalence is independent of demographic factors and presenting skin conditions. The data from the questionnaires relied on the accuracy of patients' self-reports. Both single variant and multivariable analyses showed a significant association between HH and the prevalence of anxiety and depression in a HH severity-dependent manner. Copyright © 2016 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

  20. Synthetic Small Molecule Inhibitors of Hh Signaling As Anti-Cancer Chemotherapeutics

    Science.gov (United States)

    Maschinot, C.A.; Pace, J.R.; Hadden, M.K.

    2016-01-01

    The hedgehog (Hh) pathway is a developmental signaling pathway that is essential to the proper embryonic development of many vertebrate systems. Dysregulation of Hh signaling has been implicated as a causative factor in the development and progression of several forms of human cancer. As such, the development of small molecule inhibitors of Hh signaling as potential anti-cancer chemotherapeutics has been a major area of research interest in both academics and industry over the past ten years. Through these efforts, synthetic small molecules that target multiple components of the Hh pathway have been identified and advanced to preclinical or clinical development. The goal of this review is to provide an update on the current status of several synthetic small molecule Hh pathway inhibitors and explore the potential of several recently disclosed inhibitory scaffolds. PMID:26310919

  1. A Hh-driven gene network controls specification, pattern and size of the Drosophila simple eyes.

    Science.gov (United States)

    Aguilar-Hidalgo, Daniel; Domínguez-Cejudo, María A; Amore, Gabriele; Brockmann, Anette; Lemos, María C; Córdoba, Antonio; Casares, Fernando

    2013-01-01

    During development, extracellular signaling molecules interact with intracellular gene networks to control the specification, pattern and size of organs. One such signaling molecule is Hedgehog (Hh). Hh is known to act as a morphogen, instructing different fates depending on the distance to its source. However, how Hh, when signaling across a cell field, impacts organ-specific transcriptional networks is still poorly understood. Here, we investigate this issue during the development of the Drosophila ocellar complex. The development of this sensory structure, which is composed of three simple eyes (or ocelli) located at the vertices of a triangular patch of cuticle on the dorsal head, depends on Hh signaling and on the definition of three domains: two areas of eya and so expression--the prospective anterior and posterior ocelli--and the intervening interocellar domain. Our results highlight the role of the homeodomain transcription factor engrailed (en) both as a target and as a transcriptional repressor of hh signaling in the prospective interocellar region. Furthermore, we identify a requirement for the Notch pathway in the establishment of en maintenance in a Hh-independent manner. Therefore, hh signals transiently during the specification of the interocellar domain, with en being required here for hh signaling attenuation. Computational analysis further suggests that this network design confers robustness to signaling noise and constrains phenotypic variation. In summary, using genetics and modeling we have expanded the ocellar gene network to explain how the interaction between the Hh gradient and this gene network results in the generation of stable mutually exclusive gene expression domains. In addition, we discuss some general implications our model may have in some Hh-driven gene networks.

  2. Horizontal drilling in Ontario

    Energy Technology Data Exchange (ETDEWEB)

    Sidey, P.; Precul, L. [Sproule Associates Ltd., Calgary, AB (Canada)

    2002-07-01

    A review of oil and gas production in Ontario was presented with particular reference to drilling activity between 1987 to mid 2002 when 1450 vertical wells were drilled, of which 1100 were for petroleum production and the remainder were for gas storage, observation wells, private gas wells and stratigraphic tests. Of the 1100 vertical wells drilled for petroleum production, 40 per cent became gas wells, 16 per cent became oil wells, 4 per cent became oil and gas wells, and 40 per cent were dry. During the same time period, 133 horizontal wells were also drilled, mostly for petroleum. The most active operator was Talisman Energy, which drilled 101 of the 133 horizontal wells. The remainder were drilled by 12 other companies. Of the horizontal wells, 64 per cent became oil wells, 19 per cent became gas wells, and 17 per cent were dry. This presentation included graphs depicting which oil and gas pools saw vertical or horizontal drilling during the designated time period, and explained how the wells were classified. Both horizontal and vertical well targets were illustrated. Particular reference was made to Talisman Energy's Lake Erie Drilling program which revealed that horizontal wells have an initial production rate that is 5 times that expected from vertical wells. The Hillman Pool case study revealed that the initial rate of the average horizontal well is less than half that of the average vertical well. Horizontal drilling in the Lake Erie Morpeth Gas pool has also been a commercial success. This paper demonstrates that operators have maintained Ontario's oil and gas production at high levels. In 1997 widespread horizontal drilling began taking place in Ontario, and since then, approximately 30 per cent of the wells drilled in the province have been horizontal. 16 figs.

  3. A spitzer space telescope study of SN 2002hh: An infrared echo from a type llP supernova

    DEFF Research Database (Denmark)

    Meikle, W. P. S.; Mattila, S.; Gerardy, C. L.;

    2006-01-01

    Stars: Supernovae: General, supernovae: individual (NGC 6946), Stars: Supernovae: Individual: Alphanumeric: SN 2002hh Udgivelsesdato: May 22......Stars: Supernovae: General, supernovae: individual (NGC 6946), Stars: Supernovae: Individual: Alphanumeric: SN 2002hh Udgivelsesdato: May 22...

  4. [Sexually transmitted infections].

    Science.gov (United States)

    De Toni, T; Fontana, I

    2002-12-01

    Sexually transmitted diseases (STD) are quite common and observed more frequently in teens. The adolescents represent a group at particular risk for STD due to biological, sociocultural and psychological factors. Undectected infections may lead to unwanted sequelae, including pelvic inflammatory disease, chronic abdominal pain, tubal scarring and increased risk of ectopic pregnancy. This paper deals with infections by Candida albicans, Chlamidia tracomatis, Neisseria gonorrheae, Gardnerella vaginalis, Treponema pallidum, Tricomonas vaginalis, Herpes simplex, Papilloma virus. In regard to gonorrhea, chlamydia, syphilis and papilloma virus, the expectation is that improved detection will decrease sequelae by early diagnosis and treatment. Prevention programs (information, use of hormonal contraception associated with condom use) and improved access to STD diagnosis and treatment services are useful to reduce the incidence of STD among young people.

  5. Normal transmitting boundary conditions

    Institute of Scientific and Technical Information of China (English)

    廖振鹏

    1996-01-01

    The multi-transmitting formula (MTF) governed by a single artificial speed is analytically developed into a generalized MTF governed by a few artificial speeds to improve its capacity in simultaneous simulation of several one-way waves propagating at different speeds.The generalized MTF is then discretized and further generalized using the space extrapolation to improve its accuracies in numerical simulation of transient waves at large angles of incidence.The above two successive generalizitions of MTF based on the notion of normal transmission lead to a compact formula of local non-reflecting boundary condition.The formula not only provides a general representation of the major schemes of existing local boundary conditions but can be used to generate new schemes,which combine advantages of different schemes.

  6. Sexually transmitted proctitis

    Directory of Open Access Journals (Sweden)

    Sidney Roberto Nadal

    2012-03-01

    Full Text Available Proctitis caused by sexually transmitted agents is usually taken for inflammatory bowel diseases, because of similar complaints, such as pain, bleeding and mucopurulent discharge, as well as the histopathology. Thus, its treatment is postponed and, sometimes, complications appear. The most common etiologic agents are Neisseria gonorrhoeae, Chlamydia trachomatis, Treponema pallidum and Herpes simplex. In order to avoid dissemination and complications, laboratory tests are essential for diagnosis and proper therapy. The objective of this article was to raise awareness to sexually transmitted diseases in proctitis etiology, as well as their diagnosis and treatment.As retites provocadas por agentes sexualmente transmissíveis são frequentemente confundidas com doenças inflamatórias intestinais, uma vez que as queixas mais comuns, que incluem dor, sangramento e secreção mucopurulenta, e o padrão histopatológico são semelhantes. Dessa maneira, o tratamento é postergado e, algumas vezes, as complicações aparecem. Os agentes mais comuns incluem a Neisseria gonorrhoeae, a Chlamydia trachomatis, o Treponema pallidum e o Herpes simplex. Exames laboratoriais sensíveis e específicos para confirmação diagnóstica são essenciais para o tratamento correto, evitando a disseminação e as sequelas. O objetivo deste artigo foi chamar a atenção para as doenças sexualmente transmissíveis na etiologia das retites, bem como seu diagnóstico e tratamento.

  7. Pancreatic stellate cells contribute pancreatic cancer pain via activation of sHH signaling pathway.

    Science.gov (United States)

    Han, Liang; Ma, Jiguang; Duan, Wanxing; Zhang, Lun; Yu, Shuo; Xu, Qinhong; Lei, Jianjun; Li, Xuqi; Wang, Zheng; Wu, Zheng; Huang, Jason H; Wu, Erxi; Ma, Qingyong; Ma, Zhenhua

    2016-04-05

    Abdominal pain is a critical clinical symptom in pancreatic cancer (PC) that affects the quality of life for PC patients. However, the pathogenesis of PC pain is largely unknown. In this study, we show that PC pain is initiated by the sonic hedgehog (sHH) signaling pathway in pancreatic stellate cells (PSCs), which is activated by sHH secreted from PC cells, and then, neurotrophic factors derived from PSCs mediate the pain. The different culture systems were established in vitro, and the expression of sHH pathway molecules, neurotrophic factors, TRPV1, and pain factors were examined. Capsaicin-evoked TRPV1 currents in dorsal root ganglion (DRG) neurons were examined by the patch-clamp technique. Pain-related behavior was observed in an orthotopic tumor model. sHH and PSCs increased the expression and secretion of TRPV1, SP, and CGRP by inducing NGF and BDNF in a co-culture system, also increasing TRPV1 current. But, suppressing sHH pathway or NGF reduced the expression of TRPV1, SP, and CGRP. In vivo, PSCs and PC cells that expressed high levels of sHH could enhance pain behavior. Furthermore, the blockade of NGF or TRPV1 significantly attenuated the pain response to mechanical stimulation compared with the control. Our results demonstrate that sHH signaling pathway is involved in PC pain, and PSCs play an essential role in the process greatly by inducing NGF.

  8. ALMA Observations of the HH 46/47 Molecular Outflow

    CERN Document Server

    Arce, Hector G; Corder, Stuartt; Garay, Guido; Noriega-Crespo, Alberto; Raga, Alejandro C; Cabrit, Sylvie

    2013-01-01

    The morphology, kinematics and entrainment mechanism of the HH 46/47 molecular outflow were studied using new ALMA Cycle 0 observations. Results show that the blue and red lobes are strikingly different. We argue that these differences are partly due to contrasting ambient densities that result in different wind components having a distinct effect on the entrained gas in each lobe. A 29-point mosaic, covering the two lobes at an angular resolution of about 3", detected outflow emission at much higher velocities than previous observations, resulting in significantly higher estimates of the outflow momentum and kinetic energy than previous studies of this source, using the CO(1-0) line. The morphology and the kinematics of the gas in the blue lobe are consistent with models of outflow entrainment by a wide-angle wind, and a simple model may describe the observed structures in the position-velocity diagram and the integrated intensity map. The red lobe exhibits a more complex structure, and there is evidence tha...

  9. The intriguing giant bow shocks near HH 131

    CERN Document Server

    wang, M; Wang, H; Yang, J; Chen, J; wang, Min; Noumaru, Junichi; Wang, Hongchi; Yang, Ji; Chen, Jiansheng

    2005-01-01

    Using the High Dispersion Spectrograph at the Subaru Telescope, echelle spectra of two giant arcs, i.e. nebulosities Cw and L associated with HH 131 in Orion are presented. Typical emission lines of Herbig-Haro objects have been detected towards Cw. With the 2.16 m telescope of National Astronomical Observatories, spectra of Nebu. C, L and K are obtained, which also show strong [SII]6717/6731, H$\\alpha$ and [NII]6583 emission lines. Position-velocity distributions of Cw and L are analyzed. The fastest radial velocity of Cw is V_r ~ -18.0 km/s. When the flow at L goes to the south, it slows down. The fastest radial velocity of L has been observed of -45.0 km/s and the slowest value is about -18.3 km/s. The similarity of the velocities and their positional connection indicate that Cw and L are physically associated. The entire flow tends to become less excited and less ionized when going further to the south (i.e., from Nebu. K, L to C). The electron densities of all the observed nebulosities are low (n_e ~ 10^...

  10. Estudio del horizonte local

    OpenAIRE

    Ros Ferré, Rosa Maria

    2009-01-01

    El estudio del horizonte es fundamental para poder facilitar las primeras observaciones de los alumnos en un centro educativo. Un simple modelo, que debe realizarse para cada centro, nos permite facilitar el estudio y la comprensión de los primeros rudimentos astronómicos. El modelo construido se presenta a su vez como un sencillo modelo de reloj ecuatorial y a partir de él se pueden construir otros modelos (horizontal y vertical).

  11. Sexually Transmitted Infections

    Directory of Open Access Journals (Sweden)

    LE Nicolle

    2005-01-01

    Full Text Available Sexually transmitted infections (STIs other than HIV have reappeared as an important public health problem in developed countries (1. In the late 1970s and early 1980s, research and treatment of the 'classic' STIs - gonorrhea, syphilis and chlamydia - were a major focus of infectious diseases practice and research. There were large outbreaks of syphilis in parts of Canada (2, penicillin-resistant Neisseria gonorrhoeae was a concern (3, and high rates of Chlamydia trachomatis infection with complications of pelvic inflammatory disease and ectopic pregnancy were being reported (4,5. Then, HIV infection emerged, with its spectre of a wasting, early death. There was no effective treatment, and safe sexual practices were embraced and adhered to by high-risk populations as the only effective way to avoid infection. These practices effectively prevented other STIs; rates of syphilis, gonorrhea and chlamydia infection plummeted in developed countries (5. For at least a decade, it appeared that HIV might be an end to all STIs, at least for some parts of the world. STIs continued unabated in developing countries, as many epidemiological and therapeutic studies explored the association of STIs with HIV infection.

  12. Medications for Sexually Transmitted Infections

    Science.gov (United States)

    ... Genitals and Urinary Tract Glands & Growth Head Neck & Nervous System Heart Infections Learning Disabilities Obesity Orthopedic Prevention Sexually Transmitted Skin Tobacco Treatments Injuries & ...

  13. Comparative evaluation of H&H and WFNS grading scales with modified H&H (sans systemic disease): A study on 1000 patients with subarachnoid hemorrhage.

    Science.gov (United States)

    Aggarwal, Ashish; Dhandapani, Sivashanmugam; Praneeth, Kokkula; Sodhi, Harsimrat Bir Singh; Pal, Sudhir Singh; Gaudihalli, Sachin; Khandelwal, N; Mukherjee, Kanchan K; Tewari, M K; Gupta, Sunil Kumar; Mathuriya, S N

    2017-03-15

    The comparative studies on grading in subarachnoid hemorrhage (SAH) had several limitations such as the unclear grading of Glasgow Coma Scale 15 with neurological deficits in World Federation of Neurosurgical Societies (WFNS), and the inclusion of systemic disease in Hunt and Hess (H&H) scales. Their differential incremental impacts and optimum cut-off values for unfavourable outcome are unsettled. This is a prospective comparison of prognostic impacts of grading schemes to address these issues. SAH patients were assessed using WFNS, H&H (including systemic disease), modified H&H (sans systemic disease) and followed up with Glasgow Outcome Score (GOS) at 3 months. Their performance characteristics were analysed as incremental ordinal variables and different grading scale dichotomies using rank-order correlation, sensitivity, specificity, positive predictive value, negative predictive value, Youden's J and multivariate analyses. A total of 1016 patients were studied. As univariate incremental variable, H&H sans systemic disease had the best negative rank-order correlation coefficient (-0.453) with respect to lower GOS (p H&H sans systemic disease had the greatest adjusted incremental impact of 0.72 (95% confidence interval (CI) 0.54-0.91) against a lower GOS as compared to 0.6 (95% CI 0.45-0.74) and 0.55 (95% CI 0.42-0.68) for H&H and WFNS grades, respectively. In multivariate categorical analysis, H&H grades 4-5 sans systemic disease had the greatest impact on unfavourable GOS with an adjusted odds ratio of 6.06 (95% CI 3.94-9.32). To conclude, H&H grading sans systemic disease had the greatest impact on unfavourable GOS. Though systemic disease is an important prognostic factor, it should be considered distinctly from grading. Appropriate cut-off values suggesting unfavourable outcome for H&H and WFNS were 4-5 and 3-5, respectively, indicating the importance of neurological deficits in addition to level of consciousness.

  14. ALMA OBSERVATIONS OF THE HH 46/47 MOLECULAR OUTFLOW

    Energy Technology Data Exchange (ETDEWEB)

    Arce, Hector G. [Department of Astronomy, Yale University, P.O. Box 208101, New Haven, CT 06520-8101 (United States); Mardones, Diego; Garay, Guido [Departamento de Astronomia, Universidad de Chile, Casilla 36-D, Santiago (Chile); Corder, Stuartt A. [Joint ALMA Observatory, Av. Alonso de Cordova 3107, Vitacura, Santiago (Chile); Noriega-Crespo, Alberto [Infrared Processing and Analysis Center, California Institute of Technology, Pasadena, CA 91125 (United States); Raga, Alejandro C. [Instituto de Ciencias Nucleares, UNAM, Ap. 70-543, 04510 D.F. (Mexico)

    2013-09-01

    The morphology, kinematics, and entrainment mechanism of the HH 46/47 molecular outflow were studied using new ALMA Cycle 0 observations. Results show that the blue and red lobes are strikingly different. We argue that these differences are partly due to contrasting ambient densities that result in different wind components having a distinct effect on the entrained gas in each lobe. A 29 point mosaic, covering the two lobes at an angular resolution of about 3'', detected outflow emission at much higher velocities than previous observations, resulting in significantly higher estimates of the outflow momentum and kinetic energy than previous studies of this source, using the CO(1-0) line. The morphology and the kinematics of the gas in the blue lobe are consistent with models of outflow entrainment by a wide-angle wind, and a simple model describes the observed structures in the position-velocity diagram and the velocity-integrated intensity maps. The red lobe exhibits a more complex structure, and there is evidence that this lobe is entrained by a wide-angle wind and a collimated episodic wind. Three major clumps along the outflow axis show velocity distribution consistent with prompt entrainment by different bow shocks formed by periodic mass ejection episodes which take place every few hundred years. Position-velocity cuts perpendicular to the outflow cavity show gradients where the velocity increases toward the outflow axis, inconsistent with outflow rotation. Additionally, we find evidence for the existence of a small outflow driven by a binary companion.

  15. THE KINEMATICS OF HH 34 FROM HST IMAGES WITH A NINE-YEAR TIME BASELINE

    Energy Technology Data Exchange (ETDEWEB)

    Raga, A. C.; Rodriguez-Gonzalez, A. [Instituto de Ciencias Nucleares, Universidad Nacional Autonoma de Mexico, Ap. 70-543, 04510 D.F. (Mexico); Noriega-Crespo, A.; Carey, S. J. [SPITZER Science Center, California Institute of Technology, CA 91125 (United States); Lora, V. [Astronomisches Rechen-Institut Zentrum fuer Astronomie der Universitaet Heidelberg, Moenchhofstr. 12-14, 69120 Heidelberg (Germany); Stapelfeldt, K. R. [Jet propulsion Laboratory, California Institute of Technology, MS 183-900, 4800 Oak Grove Drive, Pasadena, CA 91109 (United States)

    2012-04-01

    We study archival HST [S II] 6716+30 and H{alpha} images of the HH 34 outflow, taken in 1998.71 and in 2007.83. The {approx}9 yr time baseline and the high angular resolution of these observations allow us to carry out a detailed proper-motion study. We determine the proper motions of the substructure of the HH 34S bow shock (from the [S II] and H{alpha} frames) and of the aligned knots within {approx}30'' from the outflow source (only from the [S II] frames). We find that the present-day motions of the knots along the HH 34 jet are approximately ballistic, and that these motions directly imply the formation of a major mass concentration in {approx}900 yr, at a position similar to the one of the present-day HH 34S bow shock. In other words, we find that the knots along the HH 34 jet will merge to form a more massive structure, possibly resembling HH 34S.

  16. Molecular observations of HH34 - Does NH3 accurately trace dense molecular gas near young stars?

    Science.gov (United States)

    Davis, C. J.; Dent, W. R. F.

    1993-03-01

    Single-dish observations in HCO(+) J = 4-3 are presented of the regions around HH34 and around HH34IRS. The former is one of the best examples of the association between Herbig-Haro shocks, optical jets, and young stellar objects. The HCO(+) and CS maps peak toward the outflow source HH34IRS and suggest the presence of a hot dense molecular core. The NH3 is confined to a peak about 4-0 arcsec east of HH34IRS and to a ridge which extends in a north-south direction and peaks about 20 arcsec south of the end of the optical jet. Thus, the NH3 observations do not trace the underlying gas density and temperature in this outflow source. Toward HH34IRS the NH3 column density is less by a factor of about 10 than toward the NH3 peak position is the HH34 region, providing evidence that the NH3 is underabundant towards the central exciting stars. This underabundance may explain the toroidal structures often seen in NH3 observations of other outflow sources.

  17. Sliding Downhill Horizontally

    Science.gov (United States)

    Zurcher, Ulrich

    2005-04-01

    We study the motion of object sliding on a rough incline plane. The coefficient of kinetic friction between the surface and the object is such that the magnitude of the gravitational force along the incline F is equal to the magnitude of the kinetic friction S. If the initial velocity of the object is along the incline, the object slides down the incline with constant velocity. We study the case when the object in launched in horizontal direction. We derive exact expressions for the terminal speed of the object and the maximum horizontal displacement of the object.

  18. Transfusion-transmitted Chagas' disease.

    Science.gov (United States)

    Wendel, S

    1998-11-01

    Transfusion-transmitted Chagas' disease has been recognized since 1952. Until recently, no cases were reported outside of Latin America. However, emigration during the past 20 years expanded its transfusional geographic borders to North America. Trypanosoma cruzi-infected donors usually are asymptomatic, often for a lifetime. This situation complicates donor screening, particularly in regions where blood bank personnel are not familiar with the risk factors and natural history of this transfusion-transmitted infection. This review addresses the main aspects of epidemiology, risks of infection, clinical symptoms in donors and recipients, preventive measures, and blood donor screening to prevent transfusion-transmitted Chagas' disease.

  19. Statistics, Uncertainty, and Transmitted Variation

    Energy Technology Data Exchange (ETDEWEB)

    Wendelberger, Joanne Roth [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-11-05

    The field of Statistics provides methods for modeling and understanding data and making decisions in the presence of uncertainty. When examining response functions, variation present in the input variables will be transmitted via the response function to the output variables. This phenomenon can potentially have significant impacts on the uncertainty associated with results from subsequent analysis. This presentation will examine the concept of transmitted variation, its impact on designed experiments, and a method for identifying and estimating sources of transmitted variation in certain settings.

  20. Horizontal Connection and Horizontal Mean Curvature in Carnot Groups

    Institute of Scientific and Technical Information of China (English)

    Kang Hai TAN; Xiao Ping YANG

    2006-01-01

    In this paper we give a geometric interpretation of the notion of the horizontal mean curvature which is introduced by Danielli-Garofalo-Nhieu and Pauls who recently introduced sub-Riemannian minimal surfaces in Carnot groups. This will be done by introducing a natural nonholonomic connection which is the restriction (projection) of the natural Riemannian connection on the horizontal bundle. For this nonholonomic connection and (intrinsic) regular hypersurfaces we introduce the notions of the horizontal second fundamental form and the horizontal shape operator. It turns out that the horizontal mean curvature is the trace of the horizontal shape operator.

  1. PROPER MOTIONS OF THE OUTER KNOTS OF THE HH 80/81/80N RADIO-JET

    Energy Technology Data Exchange (ETDEWEB)

    Masqué, Josep M.; Rodriguez, Luis F.; Carrasco-González, Carlos [Instituto de Radioastronomía y Astrofísica, Universidad Nacional Autónoma de México, Morelia 58089, México (Mexico); Araudo, Anabella [University of Oxford, Astrophysics, Keble Road, Oxford OX1 3RH (United Kingdom); Estalella, Robert [Departament d’Astronomia i Meteorologia and Institut de Ciències del Cosmos (IEEC-UB), Universitat de Barcelona, Martí i Franquès 1, E-08028 Barcelona, Catalunya (Spain); Anglada, Guillem; Osorio, Mayra [Instituto de Astrofísica de Andalucía (CSIC), Apartado 3004, E-18080 Granada (Spain); Girart, Josep M. [Institut de Ciències de l’Espai (CSIC-IEEC), Campus UAB, Carrer de Can Magrans, S/N, E-08193 Cerdanyola del Vallès, Catalunya (Spain)

    2015-11-20

    The radio-knots of the Herbig–Haro (HH) 80/81/80N jet extend from the HH 80 object to the recently discovered Source 34 and has a total projected jet size of 10.3 pc, constituting the largest collimated radio-jet system known so far. It is powered by the bright infrared source IRAS 18162−2048 associated with a massive young stellar object. We report 6 cm JVLA observations that, compared with previous 6 cm VLA observations carried out in 1989, allow us to derive proper motions of the HH 80, HH 81, and HH 80N radio knots located about 2.5 pc away in projection from the powering source. For the first time, we measure proper motions of the optically obscured HH 80N object providing evidence that this knot, along with HH 81 and HH 80 are associated with the same radio-jet. We also confirm the presence of Source 34, located further north of HH 80N, previously proposed to belong to the jet.We derived that the tangential velocity of HH 80N is 260 km s{sup −1} and has a direction in agreement with the expected direction of a ballistic precessing jet. The HH 80 and HH 81 objects have tangential velocities of 350 and 220 km s{sup −1}, respectively, but their directions are somewhat deviated from the expected jet path. The velocities of the HH objects studied in this work are significantly lower than those derived for the radio knots of the jet close to the powering source (600–1400 km s{sup −1}) suggesting that the jet is slowing down due to a strong interaction with the ambient medium. As a result, since HH 80 and HH 81 are located near the edge of the cloud, the inhomogeneous and low density medium may contribute to skew the direction of their determined proper motions. The HH 80 and HH 80N emission at 6 cm is, at least in part, probably synchrotron radiation produced by relativistic electrons in a magnetic field of 1 mG. If these electrons are accelerated in a reverse adiabatic shock, we estimate a jet total density of ≲1000 cm{sup −3}. All of these

  2. Molecular hydrogen and excitation in the HH 1-2 system

    Science.gov (United States)

    Noriega-Crespo, A.; Garnavich, P. M.

    1994-01-01

    We present a series of molecular hydrogen images of the Herbig-Haro 1-2 system in the 1-0 S(1) transition at 2.121 microns, with a spatial resolution of approximately 2 sec. The distribution of H2 is then compared with that of the excitation, given by the (S II) 6717+6731 to H-alpha line ratio. We find that most optical condensations in the HH 1-2 system, including the VLA 1 jet, have H2 counterparts. H2 emission is detected in most low excitation knots, as expected for low velocity shocks (50 km/s less than), but also in high excitation regions, like in HH 1F and HH 2A min. For these latter objects, the H2 emission could be due to the interaction of the preionizing flux, produced by 150-200 km/s shocks, with the surrounding interstellar matter, i.e., fluorescence. The lack fluorescent lines in the ultraviolet (UV), however, suggest a different mechanism. H2 is detected at the tip of the VLA 1 jet, where the knot morphology suggests the presence of a second bow shock. H2 is detected also SE of HH 2E and SW of HH 1F, in regions with known NH3 emission.

  3. Horizontally mounted solar collector

    Science.gov (United States)

    Black, D. H. (Inventor)

    1979-01-01

    Solar energy is collected by using a vertical deflector assembly, a stationary reflector and a horizontally mounted solar collector. The deflector assembly contains a plurality of vanes which change the direction of the solar energy to the vertical, while constantly keeping the same side of the deflector facing the sun. The vertical rays are then reflected off the stationary reflector and are then absorbed by the collector.

  4. The Sinorhizobium fredii HH103 Genome: A Comparative Analysis With S. fredii Strains Differing in Their Symbiotic Behavior With Soybean.

    Science.gov (United States)

    Vinardell, José-María; Acosta-Jurado, Sebastián; Zehner, Susanne; Göttfert, Michael; Becker, Anke; Baena, Irene; Blom, Jochem; Crespo-Rivas, Juan Carlos; Goesmann, Alexander; Jaenicke, Sebastian; Krol, Elizaveta; McIntosh, Matthew; Margaret, Isabel; Pérez-Montaño, Francisco; Schneiker-Bekel, Susanne; Serranía, Javier; Szczepanowski, Rafael; Buendía, Ana-María; Lloret, Javier; Bonilla, Ildefonso; Pühler, Alfred; Ruiz-Sainz, José-Enrique; Weidner, Stefan

    2015-07-01

    Sinorhizobium fredii HH103 is a fast-growing rhizobial strain infecting a broad range of legumes including both American and Asiatic soybeans. In this work, we present the sequencing and annotation of the HH103 genome (7.25 Mb), consisting of one chromosome and six plasmids and representing the structurally most complex sinorhizobial genome sequenced so far. Comparative genomic analyses of S. fredii HH103 with strains USDA257 and NGR234 showed that the core genome of these three strains contains 4,212 genes (61.7% of the HH103 genes). Synteny plot analysis revealed that the much larger chromosome of USDA257 (6.48 Mb) is colinear to the HH103 (4.3 Mb) and NGR324 chromosomes (3.9 Mb). An additional region of the USDA257 chromosome of about 2 Mb displays similarity to plasmid pSfHH103e. Remarkable differences exist between HH103 and NGR234 concerning nod genes, flavonoid effect on surface polysaccharide production, and quorum-sensing systems. Furthermore a number of protein secretion systems have been found. Two genes coding for putative type III-secreted effectors not previously described in S. fredii, nopI and gunA, have been located on the HH103 genome. These differences could be important to understand the different symbiotic behavior of S. fredii strains HH103, USDA257, and NGR234 with soybean.

  5. First Design of a Proton Collimation System for 50 TeV FCC-hh

    CERN Document Server

    Fiascaris, Maria; Mirarchi, Daniele; Redaelli, Stefano

    2016-01-01

    We present studies aimed at defining a first conceptual solution for a collimation system for the hadron-hadron option for the Future Circular Collider (FCC-hh). The baseline collimation layout is based on the scaling of the present LHC collimation system to the FCC-hh energy. It currently includes a dedicated betatron cleaning insertion as well as collimators in the experimental insertions to protect the inner triplets. An aperture model for the FCC-hh is defined and the geometrical acceptance is calculated at top energy taking into account mechanical and optics imperfections. Based on these studies the collimator settings needed to protect the machine are defined. The performance of the collimation system is then assessed with particle tracking simulation tools assuming a perfect machine.

  6. Cross-talk studies between FCC-hh Experimental Interaction Regions

    CERN Document Server

    Abelleira, Jose; Appleby, Robert Barrie; Rafique, Haroon; Besana, Maria Ilaria

    2017-01-01

    Debris from 50 TeV proton-proton collisions at the main interaction point in the FCC-hh may contribute to the background in the subsequent detector. This cross-talk is of possible concern for the FCC-hh due to the high luminosity and energy of the collider. DPMJET-III is used as a collision debris generator in order to assess the muon cross-talk contribution. An analytical calculation of muon range in rock is performed. This is followed by a full Monte Carlo simulation using FLUKA, where the accelerator tunnel has been modelled. The muon cross talk between the adjacent interaction points is assessed and its implications for FCC-hh design are discussed.

  7. Analytical parametrization and shape classification of anomalous HH production in EFT approach

    CERN Document Server

    Carvalho Antunes De Oliveira, Alexandra; De Castro Manzano, Pablo; Dorigo, Tommaso; Goertz, Florian; Gouzevitch, Maxime; Tosi, Mia

    2016-01-01

    In this document we study the effect of anomalous Higgs boson couplings on non-resonant pair production of Higgs bosons (HH) at the LHC. We explore the space of the five parameters $\\kappa_\\lambda$, $\\kappa_t$, $c_2$, $c_{g}$, and $c_{2g}$ in terms of the corresponding kinematics of the final state, and describe a suggested partition of the space into a limited number of regions featuring similar phenomenology in the kinematics of HH final state, along with a corresponding set of representative benchmark points. We also provide an analytical parametrization of the cross-section modifications that the variation of anomalous couplings produces with respect to standard model HH production along with a recipe to translate our results into other parameter-space bases. Finally, we provide a preliminary analysis of variations in the topology of the final state within each region based on recent LHC results.

  8. COLLISIONALLY EXCITED FILAMENTS IN HUBBLE SPACE TELESCOPE Hα AND Hβ IMAGES OF HH 1/2

    Energy Technology Data Exchange (ETDEWEB)

    Raga, A. C.; Castellanos-Ramírez, A. [Instituto de Ciencias Nucleares, Universidad Nacional Autónoma de México, Ap. 70-543, 04510 México, D.F. (Mexico); Reipurth, B.; Chiang, Hsin-Fang [Institute for Astronomy, University of Hawaii at Manoa, Hilo, HI 96720 (United States); Bally, J., E-mail: raga@nucleares.unam.mx [Center for Astrophysics and Space Astronomy, University of Colorado, UCB 389, Boulder, CO 80309 (United States)

    2015-01-01

    We present new Hα and Hβ images of the HH 1/2 system, and we find that the Hα/Hβ ratio has high values in ridges along the leading edges of the HH 1 bow shock and of the brighter condensations of HH 2. These ridges have Hα/Hβ = 4 → 6, which is consistent with collisional excitation from the n = 1 to the n = 3 and 4 levels of hydrogen in a gas of temperatures T = 1.5 → 10 × 10{sup 4} K. This is therefore the first direct evidence that the collisional excitation/ionization region of hydrogen just behind Herbig-Haro shock fronts is detected.

  9. An alternating periodic-chaotic ISI sequence of HH neuron under external sinusoidal stimulus

    Institute of Scientific and Technical Information of China (English)

    Jin Wu-Yin; Xu Jian-Xue; Wu Ying; Hong Ling

    2004-01-01

    A study of Hodgkin-Huxley (HH) neuron under external sinusoidal excited stimulus is presented in this paper. As is well known, the stimulus frequency is to be considered as a bifurcate parameter, and numerous phenomena, such as synchronization, period, and chaos appear alternatively with the changing of the stimulus frequency. For the stimulus frequency less than 2fB (fB being the base frequency in this paper), the simulation results demonstrate that the single HH neuron could completely convey the sinusoidal signal in anti-phase into interspike interval (ISI) sequences. We also report, perhaps for the first time, another kind of phenomenon, the beat phenomenon, which exists in the phase dynamics of the ISI sequences of the HH neuron stimulated by a sinusoidal current. It is shown furthermore that intermittent transition results in the general route to chaos.

  10. Horizontal drilling activity in Manitoba

    Energy Technology Data Exchange (ETDEWEB)

    Fox, J.

    1997-04-01

    An update of horizontal well drilling in Manitoba was provided. Manitoba`s productive formations are: (1) the Bakken Formation, (2) the Lodgepole Formation, (3) the Mission Canyon Formation, (4) the Amaranth Formation, and (5) the Melita Formation. A total of 28 exploratory wells and 29 development wells, including 11 horizontal wells were drilled in 1996. The 11 horizontal wells accounted for 30 per cent of the drilling meterage. The leading drillers for horizontal wells in Manitoba are Tundra Oil and Gas, Chevron, Anderson and HCO. Production from horizontal wells in 1996 totaled 310 cubic meter per day. To date, no horizontal wells have been drilled in the Bakken Formation. The least successful horizontal well application has been in the Lodgepole Formation. A summary of horizontal well production was provided for each Formation. 4 tabs., 10 figs.

  11. Updates on the optics of the future hadron-hadron collider FCC-hh

    CERN Document Server

    Chance, Antoine; Dalena, Barbara; Holzer, Bernhard; Langner, Andy Sven; Schulte, Daniel

    2017-01-01

    The FCC-hh (Future Hadron-Hadron Circular Collider) is one of the three options considered for the next generation accelerator in high-energy physics as recommended by the European Strategy Group. The layout of FCC-hh has been optimized to a more compact design following recommendations from civil engineering aspects. The updates on the first order and second order optics of the ring will be shown for collisions at the required centre-of-mass energy of 100 TeV. Special emphasis is put on the dispersion suppressors and general beam cleaning sections as well as first considerations of injection and extraction sections.

  12. Test of the triple Higgs boson form factor in $\\mu^-\\mu^+\\to HH$

    CERN Document Server

    Gounaris, G J

    2016-01-01

    We study the sensitivity of the process $\\mu^-\\mu^+\\to HH$ to the $q^2$-dependence of the $HHH$ form factor, which can reflect the Higgs boson structure, especially in the case of compositeness. We compute the Born and 1 loop SM contribution to this process. We then show how the $\\mu^-\\mu^+\\to HH$ polarized and unpolarized cross sections are modified by the presence of various types of anomalous contributions to the $HHH$ form factor, in particular Higgs constituents in the case of compositeness.

  13. Cell penetrable humanized-VH/V(HH that inhibit RNA dependent RNA polymerase (NS5B of HCV.

    Directory of Open Access Journals (Sweden)

    Kanyarat Thueng-in

    Full Text Available NS5B is pivotal RNA dependent RNA polymerase (RdRp of HCV and NS5B function interfering halts the virus infective cycle. This work aimed to produce cell penetrable humanized single domain antibodies (SdAb; VH/V(HH that interfere with the RdRp activity. Recombinant NS5BΔ55 of genotype 3a HCV with de novo RNA synthetic activity was produced and used in phage biopanning for selecting phage clones that displayed NS5BΔ55 bound VH/V(HH from a humanized-camel VH/V(HH display library. VH/V(HH from E. coli transfected with four selected phage clones inhibited RdRp activity when tested by ELISA inhibition using 3'di-cytidylate 25 nucleotide directed in vitro RNA synthesis. Deduced amino acid sequences of two clones showed V(HH hallmark and were designated V(HH6 and V(HH24; other clones were conventional VH, designated VH9 and VH13. All VH/V(HH were linked molecularly to a cell penetrating peptide, penetratin. The cell penetrable VH9, VH13, V(HH6 and V(HH24 added to culture of Huh7 cells transfected with JHF-1 RNA of genotype 2a HCV reduced the amounts of RNA intracellularly and in culture medium implying that they inhibited the virus replication. VH/V(HH mimotopes matched with residues scattered on the polymerase fingers, palm and thumb which were likely juxtaposed to form conformational epitopes. Molecular docking revealed that the antibodies covered the RdRp catalytic groove. The transbodies await further studies for in vivo role in inhibiting HCV replication.

  14. Transfusional transmitted viruses in pregnancy.

    Science.gov (United States)

    Eleftheriou, A; Kalakoutis, G; Pavlides, N

    1998-01-01

    Blood has long been recognized as a vehicle for transmission of infectious organisms and as molecular laboratory technology has advanced, a seemingly endless array of infectious agents has occasionally been documented to be blood transmitted. Transfusion associated hepatitis (TAH) has been the most common serious consequence of blood transfusion although in recent years this has been significantly reduced (blood donor screening, blood processing, etc.). Thalassaemia major is classically associated with increased susceptibility to infections caused by those agents that are blood transmitted such as HBV, HCV, HIV, CMV, HPV B-19 (frequency rates vary from country to country). Monitoring the prevalence of transfusion transmitted infections in thalassaemics has been in recent years an indispensable part of their clinical management protocol. As a number of these viruses have been documented to be efficiently transmitted through the vertical route, the issue of blood transmitted viral infection monitoring becomes particularly important in order to provide protection or treatment both to the pregnant thalassaemic patient herself and to her foetus/newborn. Hepatitis (mainly B and C) and HIV in the obstetric thalassaemic is what the clinician is faced with most frequently. Although preventative measures have been very successful in the case of HBV infection and recently to an encouraging extent in the case of HIV (recommendations have been constructed), the mechanisms and frequency of HCV vertical transmission as well as the clinical outcome of children born to HCV carriers are not yet completely clarified. No vaccines are available and HIGB or antivirals do not appear to offer protection to the foetus against infection with HCV. Thalassaemics are frequently seropositive to markers of other transfusion transmitted viruses, such as CMV and HPV B-19, particularly by the age of pregnancy. Infection with a second or multiple strains as well as reactivation of existing CMV

  15. 76 FR 66855 - United States Savings Bonds, Series EE, HH and I

    Science.gov (United States)

    2011-10-28

    ... Fiscal Service 31 CFR Parts 351, 353, 359, and 360 United States Savings Bonds, Series EE, HH and I... be able to obtain paper Series I savings bonds with their tax refunds through Internal Revenue.... 0 7. Revise Sec. 351.46 to read as follows: Sec. 351.46 May I purchase definitive Series EE...

  16. Data of evolutionary structure change: 1JHKH-2V7HH [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available equence>AFSLE---TTAYL e>EEE --- EEE> H 2V7HH TFTADTSSNTAYM ...>EEEEE EEEEE> ATOM 5465 CA THR H 69 25.885 18.472 40.39...dbChain> 1JHKH GNSAY---WGQGT > EEE--- E...entryIDChain> YWAYDFDYWGQGT > EE E

  17. HH-MIP: An Enhancement of Mobile IP by Home Agent Handover

    Directory of Open Access Journals (Sweden)

    Jeng-Yueng Chen

    2010-01-01

    Full Text Available We propose an enhancement of Mobile IP (MIP called MIP with Home Agent Handover (HH-MIP to enjoy most of the advantages of Route Optimization MIP (ROMIP but with only a small increase of signaling overhead. In HH-MIP, the concept of Temporary HA (THA is proposed and the mobile host (MH registers the new CoA with its THA rather than its original HA. Since the THA of an MH is selected to be close to the current location of MH, HH-MIP reduces the handoff latency and shortens the signaling path of registration as well. Moreover, HH-MIP adopts an aggressive approach in selecting THA for an MH, that is, whenever an MH is moving away from its HA or previous THA, the MH triggers the handover of THA. Theoretical analysis demonstrates that the proposed scheme enjoys small handoff latency as well as routing efficiency, and the signaling cost of the proposed scheme is significantly less than that in ROMIP.

  18. Overview of design development of FCC-hh Experimental Interaction Regions

    CERN Document Server

    Seryi, Andrei; Cruz Alaniz, Emilia; Van Riesen-Haupt, Leon; Benedikt, Michael; Besana, Maria Ilaria; Buffat, Xavier; Burkhardt, Helmut; Cerutti, Francesco; Langner, Andy Sven; Martin, Roman; Riegler, Werner; Schulte, Daniel; Tomas Garcia, Rogelio; Appleby, Robert Barrie; Rafique, Haroon; Barranco Garcia, Javier; Pieloni, Tatiana; Boscolo, Manuela; Collamati, Francesco; Nevay, Laurence James; Hofer, Michael

    2017-01-01

    The experimental interaction region (EIR) is one of the key areas that define the performance of the Future Circular Collider. In this overview we will describe the status and the evolution of the design of EIR of FCC-hh, focusing on design of the optics, energy deposition in EIR elements, beam-beam effects and machine detector interface issues.

  19. Fgf19 regulated by Hh signaling is required for zebrafish forebrain development.

    Science.gov (United States)

    Miyake, Ayumi; Nakayama, Yoshiaki; Konishi, Morichika; Itoh, Nobuyuki

    2005-12-01

    Fibroblast growth factor (Fgf) signaling plays important roles in brain development. Fgf3 and Fgf8 are crucial for the formation of the forebrain and hindbrain. Fgf8 is also required for the midbrain to form. Here, we identified zebrafish Fgf19 and examined its roles in brain development by knocking down Fgf19 function. We found that Fgf19 expressed in the forebrain, midbrain and hindbrain was involved in cell proliferation and cell survival during embryonic brain development. Fgf19 was also essential for development of the ventral telencephalon and diencephalon. Regional specification is linked to cell type specification. Fgf19 was also essential for the specification of gamma-aminobutyric acid (GABA)ergic interneurons and oligodendrocytes generated in the ventral telencephalon and diencephalon. The cross talk between Fgf and Hh signaling is critical for brain development. In the forebrain, Fgf19 expression was down-regulated on inhibition of Hh but not of Fgf3/Fgf8, and overexpression of Fgf19 rescued partially the phenotype on inhibition of Hh. The present findings indicate that Fgf19 signaling is crucial for forebrain development by interacting with Hh and provide new insights into the roles of Fgf signaling in brain development.

  20. The time evolution of HH~2 from four epochs of HST images

    CERN Document Server

    Raga, A C; Velázquez, P F; Esquivel, A; Bally, J

    2016-01-01

    We have analyzed four epochs of H$\\alpha$ and [S~II] HST images of the HH~1/2 outflow (covering a time interval from 1994 to 2014) to determine proper motions and emission line fluxes of the knots of HH~2. We find that our new proper motions agree surprisingly well with the motions measured by Herbig \\& Jones (1981), although there is partial evidence for a slight deceleration of the motion of the HH~2 knots from 1945 to 2014. We also measure the time-variability of the H$\\alpha$ intensities and the [S~II]/H$\\alpha$ line ratios, and find that knots H and A have the largest intensity variabilities (in $1994\\to 2014$). Knot H (which now dominates the HH~2 emission) has strengthened substantially, while keeping an approximately constant [S~II]/H$\\alpha$ ratio. Knot A has dramatically faded, and at the same time has had a substantial increase in its [S~II]/H$\\alpha$ ratio. Possible interpretations of these results are discussed.

  1. The HhH domain of the human DNA repair protein XPF forms stable homodimers.

    Science.gov (United States)

    Das, Devashish; Tripsianes, Konstantinos; Jaspers, Nicolaas G J; Hoeijmakers, Jan H J; Kaptein, Robert; Boelens, Rolf; Folkers, Gert E

    2008-03-01

    The human XPF-ERCC1 protein complex plays an essential role in nucleotide excision repair by catalysing positioned nicking of a DNA strand at the 5' side of the damage. We have recently solved the structure of the heterodimeric complex of the C-terminal domains of XPF and ERCC1 (Tripsianes et al., Structure 2005;13:1849-1858). We found that this complex comprises a pseudo twofold symmetry axis and that the helix-hairpin-helix motif of ERCC1 is required for DNA binding, whereas the corresponding domain of XPF is functioning as a scaffold for complex formation with ERCC1. Despite the functional importance of heterodimerization, the C-terminal domain of XPF can also form homodimers in vitro. We here compare the stabilities of homodimeric and heterodimeric complexes of the C-terminal domains of XPF and ERCC1. The higher stability of the XPF HhH complexes under various experimental conditions, determined using CD and NMR spectroscopy and mass spectrometry, is well explained by the structural differences that exist between the HhH domains of the two complexes. The XPF HhH homodimer has a larger interaction interface, aromatic stacking interactions, and additional hydrogen bond contacts as compared to the XPF/ERCC1 HhH complex, which accounts for its higher stability.

  2. Well Spacing for Horizontal Wells

    Directory of Open Access Journals (Sweden)

    C.D.S. Keuengoua

    2011-06-01

    Full Text Available In the developing phase of a hydrocarbon reservoir and planning for drilling the production wells, it is necessary to drill the wells in an appropriate spacing to achieve maximum economic revenues during the reservoir life span. Well spacing which is the real location and interrelationship between producing oil or gas wells in an oil field is an important parameter. It is determined for the maximum ultimate production of a given reservoir and should be taken in consideration during well planning to avoid drilling of unnecessary wells. This study presents the concept of drainage area on horizontal well and horizontal productivity indices with different equations and their applications. A user friendly Excel Spreadsheet program was developed to calculate the productivity values of horizontal wells using three major available productivity equations. Also, the developed spreadsheet program was used to evaluate the effect of well spacing on the productivities of horizontal wells using productivity index approach and drainage area concept. It also helps to review the comparison between vertical and horizontal wells spacing based on drainage area concept. This program was validated, and then was used to study the effect of horizontal well length on the ratio of horizontal well productivity to vertical well productivity. The results show that higher ratio of horizontal well productivity to vertical well productivity values are obtained with increase length of the horizontal well. It is a very useful tool for making decision about the application of well spacing for horizontal wells.

  3. CRISPR/Cas9-mediated Dax1 knockout in the monkey recapitulates human AHC-HH.

    Science.gov (United States)

    Kang, Yu; Zheng, Bo; Shen, Bin; Chen, Yongchang; Wang, Lei; Wang, Jianying; Niu, Yuyu; Cui, Yiqiang; Zhou, Jiankui; Wang, Hong; Guo, Xuejiang; Hu, Bian; Zhou, Qi; Sha, Jiahao; Ji, Weizhi; Huang, Xingxu

    2015-12-20

    Mutations in the DAX1 locus cause X-linked adrenal hypoplasia congenita (AHC) and hypogonadotropic hypogonadism (HH), which manifest with primary adrenal insufficiency and incomplete or absent sexual maturation, respectively. The associated defects in spermatogenesis can range from spermatogenic arrest to Sertoli cell only syndrome. Conclusions from Dax1 knockout mouse models provide only limited insight into AHC/HH disease mechanisms, because mouse models exhibit more extensive abnormalities in testicular development, including disorganized and incompletely formed testis cords with decreased number of peritubular myoid cells and male-to-female sex reversal. We previously reported successful clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9)-mediated genome targeting in cynomolgus monkeys. Here, we describe a male fetal monkey in which targeted genome editing using CRISPR/Cas9 produced Dax1-null mutations in most somatic tissues and in the gonads. This DAX1-deficient monkey displayed defects in adrenal gland development and abnormal testis architecture with small cords, expanded blood vessels and extensive fibrosis. Sertoli cell formation was not affected. This phenotype strongly resembles findings in human patients with AHC-HH caused by mutations in DAX1. We further detected upregulation of Wnt/β-catenin-VEGF signaling in the fetal Dax1-deficient testis, suggesting abnormal activation of signaling pathways in the absence of DAX1 as one mechanism of AHC-HH. Our study reveals novel insight into the role of DAX1 in HH and provides proof-of-principle for the generation of monkey models of human disease via CRISPR/Cas9-mediated gene targeting.

  4. Crustacean hyperglycemic hormone (cHH as a modulator of aggression in crustacean decapods.

    Directory of Open Access Journals (Sweden)

    Laura Aquiloni

    Full Text Available Biogenic amines, particularly serotonin, are recognised to play an important role in controlling the aggression of invertebrates, whereas the effect of neurohormones is still underexplored. The crustacean Hyperglycemic Hormone (cHH is a multifunctional member of the eyestalk neuropeptide family. We expect that this neuropeptide influences aggression either directly, by controlling its expression, or indirectly, by mobilizing the energetic stores needed for the increased activity of an animal. Our study aims at testing such an influence and the possible reversion of hierarchies in the red swamp crayfish, Procambarus clarkii, as a model organism. Three types of pairs of similarly sized males were formed: (1 'control pairs' (CP, n = 8: both individuals were injected with a phosphate saline solution (PBS; (2 'reinforced pairs' (RP, n = 9: the alpha alone was injected with native cHH, and the beta with PBS; (3 'inverted pairs' (IP, n = 9: the opposite of (2. We found that, independently of the crayfish's prior social experience, cHH injections induced (i the expression of dominance behaviour, (ii higher glycemic levels, and (iii lower time spent motionless. In CP and RP, fight intensity decreased with the establishment of dominance. On the contrary, in IP, betas became increasingly likely to initiate and escalate fights and, consequently, increased their dominance till a temporary reversal of the hierarchy. Our results demonstrate, for the first time, that, similarly to serotonin, cHH enhances individual aggression, up to reverse, although transitorily, the hierarchical rank. New research perspectives are thus opened in our intriguing effort of understanding the role of cHH in the modulation of agonistic behaviour in crustaceans.

  5. Horizontal displacements contribution to tsunami wave energy balance

    CERN Document Server

    Dutykh, Denys; Chubarov, Leonid; Shokin, Yuriy

    2010-01-01

    The main reason for the generation of tsunamis is the deformation of the bottom of the ocean caused by an underwater earthquake. Usually, only the vertical bottom motion is taken into accound while the horizontal displacements are neglected. In the present paper we study both the vertical and the horizontal bottom motion while we propose a novel methodology for reconstructing the bottom coseismic displacements field which is transmitted to the free surface using a new three-dimensional Weakly Nonlinear (WN) approach. We pay a special attention to the evolution of kinetic and potential energies of the resulting wave while the contribution of horizontal displacements into wave energy balance is also quantified. Approaches proposed in this study are illustrated on the July 17, 2006 Java tsunami.

  6. PRODUCTIVITY OF FRACTURED HORIZONTAL WELLS

    Directory of Open Access Journals (Sweden)

    Stjepan Antolović

    2009-12-01

    Full Text Available The interest and performance of horizontal drilling and completions has increased during the last two decades. Horizontal wells are advantageous compared to vertical wells in thin reservoirs, reservoirs with favorable vertical permeability and reservoirs with water and gas coning problems. In many reservoirs, the ratio of horizontal permeability to the vertical permeability is substantially larger than one and often is close to 10. Thus, these reservoirs are very good candidates for hydraulic fracturing. By hydraulic fracturing one or more fractures are created, which can be longitudinal or orthogonal. By that, flow is altered and it mostly conducts horizontally through reservoir toward horizontal wellbore. With this altered flow, fluid is produced faster, with less pressure loss by fluid unit of produced fluid. Some of the existing mathematical models to determine the productivity of multifractured horizontal wells are presented in this work (the paper is published in Croatian.

  7. Plant-mediated interspecific horizontal transmission of an intracellular symbiont in insects

    KAUST Repository

    Gonella, Elena

    2015-11-13

    Intracellular reproductive manipulators, such as Candidatus Cardinium and Wolbachia are vertically transmitted to progeny but rarely show co-speciation with the host. In sap-feeding insects, plant tissues have been proposed as alternative horizontal routes of interspecific transmission, but experimental evidence is limited. Here we report results from experiments that show that Cardinium is horizontally transmitted between different phloem sap-feeding insect species through plants. Quantitative PCR and in situ hybridization experiments indicated that the leafhopper Scaphoideus titanus releases Cardinium from its salivary glands during feeding on both artificial media and grapevine leaves. Successional time-course feeding experiments with S. titanus initially fed sugar solutions or small areas of grapevine leaves followed by feeding by the phytoplasma vector Macrosteles quadripunctulatus or the grapevine feeder Empoasca vitis revealed that the symbionts were transmitted to both species. Explaining interspecific horizontal transmission through plants improves our understanding of how symbionts spread, their lifestyle and the symbiont-host intermixed evolutionary pattern.

  8. Sexually transmitted diseases and anorectum.

    OpenAIRE

    VAN KEMSEKE, Catherine

    2009-01-01

    Sexually transmitted diseases (STD) are a major public health problem because their incidence is increasing worldwide despite prevention campaigns and because they raise the risk of HIV infection. Anorectal localisations of STD are common among men who have sex with men (MSM) but can also be seen among heterosexuals (men or women). Transmission of such infections is due to anal sex or to other sexual behaviours like "fisting". Although some pathogens (like Human Papillomavirus-HPV) are common...

  9. Di-Higgs phenomenology in tt¯hh: The forgotten channel

    Directory of Open Access Journals (Sweden)

    Christoph Englert

    2015-04-01

    Full Text Available Searches for multi-Higgs final states allow to constrain parameters of the SM (or extensions thereof that directly relate to the mechanism of electroweak symmetry breaking. Multi-Higgs production cross sections, however, are small and the phenomenologically accessible final states are challenging to isolate in the busy multi-jet hadron collider environment of the LHC run 2 and HL-LHC. This makes the necessity to extend the list of potentially observable production mechanisms obvious. Most of the phenomenological analyses in the past have focused on gg→hh+jets; in this paper we study pp→tt¯hh at the HL-LHC and find that this channel for h→bb¯ and semi-leptonic and hadronic top decays has the potential to provide an additional handle to constrain the Higgs trilinear coupling in a global fit at the end of the high luminosity phase.

  10. VLA Detection of the Exciting Sources of the HH 288 and HHL59 Outflows

    Directory of Open Access Journals (Sweden)

    Mónica Rodríguez

    2002-01-01

    Full Text Available Presentamos observaciones hechas con el VLA a 3.6 cm hacia tres campos conteniendo flujos moleculares, incluyendo a la región de HHL59, cuyo flujo molecular en CO se reporta en este artículo. Detectamos candidatos para las fuentes excitadoras de los flujos moleculares en los tres campos observados: L1287, HH 288 y HHL59. La fuente excitadora de L1287 se ha reportado anteriormente, pero aquellas hacia HH 288 y HHL59 se presentan aquí por vez primera. Discutimos los parámetros de estas fuentes, así como su relación con fuentes detectadas a otras longitudes de onda.

  11. Progress towards next generation hadron colliders: FCC-hh, HE-LHC, and SPPC

    Science.gov (United States)

    Zimmermann, Frank; EuCARD-2 Extreme Beams Collaboration; Future Circular Collider (FCC) Study Collaboration

    2017-01-01

    A higher-energy circular proton collider is generally considered to be the only path available in this century for exploring energy scales well beyond the reach of the Large Hadron Collider (LHC) presently in operation at CERN. In response to the 2013 Update of the European Strategy for Particle Physics and aligned with the 2014 US ``P5'' recommendations, the international Future Circular Collider (FCC) study, hosted by CERN, is designing such future frontier hadron collider. This so-called FCC-hh will provide proton-proton collisions at a centre-of-mass energy of 100 TeV, with unprecedented luminosity. The FCC-hh energy goal is reached by combining higher-field, 16 T magnets, based on Nb3Sn superconductor, and a new 100 km tunnel connected to the LHC complex. In addition to the FCC-hh proper, the FCC study is also exploring the possibility of a High-Energy LHC (HE-LHC), with a centre-of-mass energy of 25-27 TeV, as could be achieved in the existing 27 km LHC tunnel using the FCC-hh magnet technology. A separate design effort centred at IHEP Beijing aims at developing and constructing a similar collider in China, with a smaller circumference of about 54 km, called SPPC. Assuming even higher-field 20 T magnets, by relying on high-temperature superconductor, the SPPC could reach a c.m. energy of about 70 TeV. This presentation will report the motivation and the present status of the R&D for future hadron colliders, a comparison of the three designs under consideration, the major challenges, R&D topics, the international technology programs, and the emerging global collaboration. Work supported by the European Commission under Capacities 7th Framework Programme project EuCARD-2, Grant Agreement 312453, and the HORIZON 2020 project EuroCirCol, Grant Agreement 654305.

  12. Exploring the $Z' \\rightarrow t\\overline{t}$ heavy resonance at FCC-hh

    CERN Document Server

    Smith, Rachel Emma Clarke

    2017-01-01

    My summer student project explored the feasibility of detecting final states with boosted top quarks at 100 TeV with the baseline FCC-hh detector. I focused specifically on the $Z' \\rightarrow t\\overline{t}$ hadronic process. I determined the exclusion cross-section of $Z' \\rightarrow t\\overline{t}$ and the integrated luminosity required to make a discovery at the baseline FCC detector at 95% confidence level.

  13. Main changes to LHC layout for reuse as FCC-hh High Energy Booster

    CERN Document Server

    AUTHOR|(SzGeCERN)396044; Wolfgang Bartmann; Werner Herr; Philippe Lebrun; Attilio Milanese

    2015-01-01

    Reuse of the LHC is one option being investigated for a High Energy Booster for injection of 3.3 TeV protons (and heavy ions at equivalent rigidity) into the proposed 100 TeV centre of mass FCC-hh collider. In this note the major changes required to the LHC layout are listed, assuming beam transfer to the FCC collider is required from both LHC Points 1 and 8.

  14. Zika Mosquito Can Transmit Other Viruses, Too

    Science.gov (United States)

    ... page: https://medlineplus.gov/news/fullstory_165752.html Zika Mosquito Can Transmit Other Viruses, Too 3-in- ... mosquito species that's the main carrier of the Zika virus might also transmit two other viruses -- chikungunya ...

  15. Hot methanol from the inner region of the HH 212 protostellar system

    CERN Document Server

    Leurini, S; Cabrit, S; Gueth, F; Giannetti, A; Bacciotti, F; Bachiller, R; Ceccarelli, C; Gusdorf, A; Lefloch, B; Podio, L; Tafalla, M

    2016-01-01

    The mechanisms leading to the formation of disks around young stellar objects (YSOs) and to the launching of the associated jets are crucial to the understanding of the earliest stages of star and planet formation. HH 212 is a privileged laboratory to study a pristine jet-disk system. Therefore we investigate the innermost region ($<100$ AU) around the HH 212-MM1 protostar through ALMA band\\,7 observations of methanol. The 8 GHz bandwidth spectrum towards the peak of the continuum emission of the HH 212 system reveals at least 19 transitions of methanol. Several of these lines (among which several vibrationally excited lines in the v$_{\\rm t}=1,2$ states) have upper energies above 500 K. They originate from a compact ($<135$ AU in diameter), hot ($\\sim 295$ K) region elongated along the direction of the SiO jet. We performed a fit in the $uv$ plane of various velocity channels of the strongest high-excitation lines. The blue- and red-shifted velocity centroids are shifted roughly symmetrically on either...

  16. A study of the wiggle morphology of HH 211 through numerical simulations

    CERN Document Server

    Moraghan, Anthony; Huang, Po-Sheng; Vaidya, Bhargav

    2016-01-01

    Recent high-resolution high-sensitivity observations of protostellar jets have shown many to possess deviations to their trajectories. HH 211 is one such example where sub-mm observations with the SMA have revealed a clear reflection-symmetric wiggle. The most likely explanation is that the HH 211 jet source could be moving as part of a protobinary system. Here we test this assumption by simulating HH 211 through 3D hydrodynamic jet propagation simulations using the PLUTO code with a molecular chemistry and cooling module, and initial conditions based on an analytical model derived from SMA observations. Our results show the reflection-symmetric wiggle can be recreated through the assumption of a jet source perturbed by binary motion at its base, and that a regular sinusoidal velocity variation in the jet beam can be close to matching the observed knot pattern. However, a more complex model with either additional heating from the protostar, or a shorter period velocity pulsation may be required to account for...

  17. FLIP-FLOP ACTIVITY ON THE W UMa-TYPE BINARY SYSTEM HH UMa

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Kun; Zhang, Xiaobin; Deng, Licai; Luo, Changqing; Luo, Yangping [Key Laboratory of Optical Astronomy, National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012 (China); Zhang, Jun, E-mail: kwang@bao.ac.cn [Key Laboratory of Solar Activity, National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012 (China)

    2015-05-20

    We report the discovery of flip-flop activity in a W UMa-type binary. A long-term multi-color photometric surveillance of HH UMa was carried out with three sets of light curves obtained over six weeks. The light curves of the eclipsing binary presented marked asymmetry and rapid interchange between the two light maxima. During the observations from 2014 February to 2014 April, the spot distortion phase jumped between phases 0.25 and 0.75 twice, a typical indication of flip-flop activity. We applied the Wilson–Devinney method to analyze the three light curves. The results indicate that HH UMa is a partially eclipsing contact system of A subtype with an obviously asymmetric light curve. The observed light curves can be modeled by assuming that there are two dark spots on the massive primary component that are almost persistently located around phases 0.25 and 0.75, but can interchange their intensities. We further suggest that a plausible scenario for explaining the properties of those dark spots is strong surface magnetic activity with a sudden reversal of the more active longitude. We therefore conclude that HH UMa is very likely a W UMa-type system displaying flip-flop activity.

  18. The counterjet of HH 30: new light on its binary driving source

    CERN Document Server

    Estalella, Robert; Anglada, Guillem; Gómez, Gabriel; Riera, Angels; Carrasco-González, Carlos

    2012-01-01

    We present new [SII] images of the HH 30 jet and counterjet observed in 2006, 2007, and 2010 that allowed us to measure with improved accuracy the positions and proper motions of the jet and counterjet knots. Our results show that the motion of the knots is essentially ballistic, with the exception of the farthest knots, which trace the large scale C-shape bending of the jet. The observed bending of the jet can be produced by a relative motion of the HH 30 star with respect to its surrounding environment, caused either by a possible proper motion of the HH 30 star, or by the entrainment of environment gas by the red lobe of the nearby L1551-IRS 5 outflow. Alternatively, the bending can be produced by the stellar wind from a nearby CTTS, identified in the 2MASS catalog. The proper motion velocities of the knots of the counterjet show more variations than those of the jet. In particular, we identify two knots of the counterjet that have the same kinematic age but whose velocities differ by almost a factor of tw...

  19. Analytical parametrization and shape classification of anomalous HH production in the EFT approach

    CERN Document Server

    Carvalho, Alexandra; Manzano, Pablo de Castro; Dorigo, Tommaso; Goertz, Florian; Gouzevich, Maxime; Tosi, Mia

    2016-01-01

    In this document we study the effect of anomalous Higgs boson couplings on non-resonant pair production of Higgs bosons ($HH$) at the LHC. We explore the space of the five parameters $\\kappa_{\\lambda}$, $\\kappa_{t}$, $c_2$, $c_g$, and $c_{2g}$ in terms of the corresponding kinematics of the final state, and describe a partition of the space into a limited number of regions featuring similar phenomenology in the kinematics of $HH$ final state. We call clusters the sets of points belonging to the same region; to each cluster corresponds a representative point which we call a benchmark. We discuss a possible technique to estimate the sensitivity of an experimental search to the kinematical differences between the phenomenology of the benchmark points and the rest of the parameter space contained in the corresponding cluster. We also provide an analytical parametrization of the cross-section modifications that the variation of anomalous couplings produces with respect to standard model $HH$ production along with ...

  20. A New Authentication Method for Vertical and Horizontal Handover in 3G-WLAN Interworking Architecture

    Directory of Open Access Journals (Sweden)

    Younes El Hajjaji El Idrissi

    2014-01-01

    Full Text Available The interworking of the 3G and the WLAN technique provides a perfect connectivity solution in terms of data rate, service cost and area coverage. However the Vertical Handover (VH from the 3G to WLAN and the Horizontal Handover (HH between WLAN domains present an additional security challenge. The V/H handover must be fast and secure without impacting the security in both networks. Several authentication methods have been proposed to secure the VH and HH. The Extensible Authentication Protocol Key Agreement (EAP-AKA is the authentication protocol adopted by the 3rd Generation Partnership Project (3GPP to authenticate User Equipment by the 3G Home Networks. The EAP-AKA protocol suffers from several weaknesses, such as user identity display and high authentication delay. In this study we propose a new simplify authentication method and key agreement for vertical and horizontal handovers based on the existed method EAP-AKA. Performances analysis of the proposed method show superior results in comparison to the existing EAP-AKA method in terms of bandwidth consumption, signaling cost and authentication delay. The security property of the new method is verified by using the formal security analyzer Automated Validation of Internet Security Protocols and Applications (AVISPA which has a high talent in finding potential attacks automatically in security protocols.

  1. Reconstruction of $\\pi^{0}$s in the Electromagnetic Calorimeter (ECAL) of the Future Circular Collider (FCC-hh)

    CERN Document Server

    AUTHOR|(CDS)2266510

    2018-01-01

    This project has been dedicated to learn about the design and optimization of detectors for the Future Circular Collider (FCC)-hh in hadron mode, with special focus on the validation of the clustering algorithm used for photon reconstruction.

  2. The electronic structure and bonding of a H-H pair in the vicinity of a BCC Fe bulk vacancy

    Energy Technology Data Exchange (ETDEWEB)

    Juan, A.; Pistonesi, C.; Brizuela, G. [Universidad Nacional del Sur, Bahia Blanca (Argentina). Departamento de Fisica; Garcia, A.J. [Universidad Nacional del Sur, Bahia Blanca (Argentina). Departamento de Ciencias de la Computacion

    2003-09-01

    The H-Fe interaction near a bcc Fe vacancy is analysed using a semi-empirical theoretical method. Calculations were performed using a Fe{sub 86} cluster with a vacancy. Hydrogen atoms are positioned in their local energy minima configurations. Changes in the electronic structure of Fe atoms near a vacancy were analysed for the system without H, with one H and with two H atoms. Fe atoms surrounding the vacancy weaken their bond when hydrogen is present. This is due to the formation of H-Fe bonds. Hydrogen influences only its nearest-neighbour Fe atoms. The H-H interaction was also analysed. For H-H distance of 0.82 Angstrom an H-H association is formed, while H-Fe interaction and Fe-Fe weakening is markedly reduced, when compared with other H-H interactions. (author)

  3. Vertically- and horizontally-transmitted memories – the fading boundaries between regeneration and inheritance in planaria

    Science.gov (United States)

    Neuhof, Moran; Levin, Michael; Rechavi, Oded

    2016-01-01

    ABSTRACT The Weismann barrier postulates that genetic information passes only from the germline to the soma and not in reverse, thus providing an obstacle to the inheritance of acquired traits. Certain organisms such as planaria – flatworms that can reproduce through asymmetric fission – avoid the limitations of this barrier, thus blurring the distinction between the processes of inheritance and development. In this paper, we re-evaluate canonical ideas about the interaction between developmental, genetic and evolutionary processes through the lens of planaria. Biased distribution of epigenetic effects in asymmetrically produced parts of a regenerating organism could increase variation and therefore affect the species' evolution. The maintenance and fixing of somatic experiences, encoded via stable biochemical or physiological states, may contribute to evolutionary processes in the absence of classically defined generations. We discuss different mechanisms that could induce asymmetry between the two organisms that eventually develop from the regenerating parts, including one particularly fascinating source – the potential capacity of the brain to produce long-lasting epigenetic changes. PMID:27565761

  4. Vertically- and horizontally-transmitted memories – the fading boundaries between regeneration and inheritance in planaria

    Directory of Open Access Journals (Sweden)

    Moran Neuhof

    2016-09-01

    Full Text Available The Weismann barrier postulates that genetic information passes only from the germline to the soma and not in reverse, thus providing an obstacle to the inheritance of acquired traits. Certain organisms such as planaria – flatworms that can reproduce through asymmetric fission – avoid the limitations of this barrier, thus blurring the distinction between the processes of inheritance and development. In this paper, we re-evaluate canonical ideas about the interaction between developmental, genetic and evolutionary processes through the lens of planaria. Biased distribution of epigenetic effects in asymmetrically produced parts of a regenerating organism could increase variation and therefore affect the species' evolution. The maintenance and fixing of somatic experiences, encoded via stable biochemical or physiological states, may contribute to evolutionary processes in the absence of classically defined generations. We discuss different mechanisms that could induce asymmetry between the two organisms that eventually develop from the regenerating parts, including one particularly fascinating source – the potential capacity of the brain to produce long-lasting epigenetic changes.

  5. Detailed optical study of HH 32 and the highly collimated outflow from the T Tauri star AS 353A

    Energy Technology Data Exchange (ETDEWEB)

    Hartigan, P.; Mundt, R.; Stocke, J.

    1986-06-01

    The T Tauri star AS 353A and its highly collimated bipolar outflow have been studied using medium- and high-resolution spectroscopy and deep emission-line CCD imagery. We report the discovery of a linear emission jet in the redshifted part of the flow, and present spectra of the HH objects (HH 32A--D) that confirm the bipolarity of the flow. Despite widely varying line profiles, all four HH objects have similar extremely broad emission linewidths and maximum radial velocities (approx.400 km/s) as well as nearly constant number density as a function of radial velocity. Three of the four objects (HH 32D is the possible exception) possess prominent double-peaked emission-line profiles, and in HH 32A and HH 32C the high-velocity component is situated closer to the star than the low-velocity component. The line profile of (O III) lambda5007 differs markedly from the profiles of lower-excitation lines for HH 32A. These characteristics are examined in the light of two physical models: HH objects as strongly radiating shocks in outflowing jets or as single bow shocks around dense clumps in the outflow. Both are successful in explaining the majority of characteristics observed, but both models encounter some difficulties. The stellar wind has been studied through examination of the star's emission and absorption lines, and we find that the wind is already accelerated to 300 km/s close to the star, and reaches a terminal velocity in excess of 350 km/s. The blueshifted component of the H..cap alpha.. profile of AS 353A is highly variable, and the profiles of different lines have quite dissimilar characteristics. The P Cygni line profiles are discussed briefly in terms of two wind models. There is evidence that the flow collimation occurs at distances greater than two stellar radii.

  6. Horizontal and Vertical Line Designs.

    Science.gov (United States)

    Johns, Pat

    2003-01-01

    Presents an art lesson in which students learn about the artist Piet Mondrian and create their own abstract artworks. Focuses on geometric shapes using horizontal and vertical lines. Includes background information about the artist. (CMK)

  7. Experimental investigation of horizontal convection

    OpenAIRE

    Muñoz Córdoba, Lucía

    2015-01-01

    Fluid circulation driven by buoyancy forces due to a thermal gradient on a horizontal boundary, known as horizontal convection, is experimentally studied. For that purpose, a methacrylate box with inner dimensions 300x150x150 mm3 (LxWxH) whose bottom is composed by a heat exchanger and a printed circuit board is lled with water. The heat exchanger provides a uniform temperature boundary condition while the printed circuit board provides a boundary condition of uniform heat ...

  8. Notification of transfusion transmitted infection.

    Science.gov (United States)

    Choudhury, Lincoln P; Tetali, Shailaja

    2008-01-01

    The National Blood Policy of India, 2002, advocates the disclosure of results of transfusion transmitted infections (TTI) to blood donors. However, in the absence of well-defined notification processes, and in order to avoid serious consequences resulting from unguided disclosure, blood bank personnel discard blood that is TTI-positive. We report on a survey of 105 voluntary blood donors in Kerala. Only two out of three participants had filled the donor form in the last year. Only half were aware that the blood bank was supposed to inform them if they tested positive for TTI. Fifty-seven per cent of donors wanted to be informed every time they donated blood, irrespective of a positive or negative result.

  9. Transfusion-transmitted parasitic infections

    Directory of Open Access Journals (Sweden)

    Singh Gagandeep

    2010-01-01

    Full Text Available The transmission of parasitic organisms through transfusion is relatively rare. Of the major transfusion-transmitted diseases, malaria is a major cause of TTIP in tropical countries whereas babesiosis and Chagas′ disease pose the greatest threat to donors in the USA In both cases, this is due to the increased number of potentially infected donors. There are no reliable serologic tests available to screen donors for any of these organisms and the focus for prevention remains on adherence to donor screening guidelines that address travel history and previous infection with the etiologic agent. One goal is the development of tests that are able to screen for and identify donors potentially infectious for parasitic infections without causing the deferral of a large number of non-infectious donors or significantly increasing costs. Ideally, methods to inactivate the infectious organism will provide an element of added safety to the blood supply.

  10. Centimeter continuum observations of the northern head of the HH 80/81/80N jet: revising the actual dimensions of a parsec scale jet

    CERN Document Server

    Masqué, Josep M; Estalella, Robert; Rodríguez, Luis F; Beltrán, Maria T

    2012-01-01

    We present 6 and 20 cm JVLA/VLA observations of the northern head of the HH 80/81/80N jet, one of the largest collimated jet systems known so far, aimed to look for knots further away than HH 80N, the northern head of the jet. Aligned with the jet and 10 arcmin northeast of HH 80N, we found a radio source not reported before, with a negative spectral index similar to that HH 80, HH 81 and HH 80N. The fit of a precessing jet model to the knots of the HH 80/81/80N jet, including the new source, shows that the position of this source is close to the jet path resulting from the modeling. If the new source belongs to the HH 80/81/80N jet, its derived size and dynamical age are 18.4 pc and >9000 yr, respectively. If the jet is symmetric, its southern lobe would expand beyond the cloud edge resulting in an asymmetric appearance of the jet. Based on the updated dynamical age, we speculate on the possibility that the HH 80/81/80N jet triggered the star formation observed in a dense core found ahead of HH 80N, which sh...

  11. Horizontal fiscal imbalance in Germany

    Directory of Open Access Journals (Sweden)

    Paweł Kowalik

    2015-04-01

    Full Text Available Regional inequalities are currently a challenge for the majority of the countries, in particular the large ones. The problem of public income redistribution emerges due to possible differentiation of the economic development level of territorial units. The most often considered problem is the vertical distribution. The horizontal division of income is far less frequently considered. Horizontal fiscal imbalance or regional tax inequalities seem to be graver than the vertical imbalance, particularly in developing countries. The public finance system, in particular in federations, is often very complex. Public finance of federations and federated states are not often based on the same assumptions. This leads to differences among regions, both vertical and horizontal. The use of the presented measures helps identify those differences and permits developing mechanisms equalising those inequalities. It should be remembered that those measures may have certain drawbacks, and they mainly focus on certain specific values of income redistribution. Thereby several measures should be applied in measurements and the obtained results should be compared. There are no up-to-date measurements and comparisons of horizontal fiscal imbalance among countries.. The aim of this paper is to measure horizontal fiscal imbalance in Germany, especially after reunification, which represents one of two models of federalism. At the beginning it shows the static and dynamic measurements presented in the literature that can be used to measure the horizontal fiscal imbalance. And then it is followed by the results of calculations for Germany in the period 1970-2013. As expected, horizontal imbalance was much lower before than after the reunification of Germany. After the reunification there were large disparities between "old" and "new" länder. This imbalance is gradually reduced. In comparison with the results obtained for the USA [Kowalik 2014, pp. 144-148] it can be said

  12. Searches for diboson resonances with ATLAS (VV, VH and HH, excl. diphoton resonance)

    CERN Document Server

    Gregersen, Kristian; The ATLAS collaboration

    2016-01-01

    An overview of ATLAS diboson resonance searches with LHC Run 2 data at 13 TeV are summarized in this talk. Resonant production of two bosons is a clear hint for physics beyond the Standard Model, potentially related to the nature of the electroweak symmetry breaking mechanism in the SM. Searches for diboson resonances have been performed in VV, VH and HH diboson channels with final states with different numbers of leptons and primarily in boosted topologies where the hadronically decaying bosons can be reconstructed as one large-radius jet.

  13. Exploring the triplet parameters space to optimise the final focus of the FCC-hh

    CERN Document Server

    Van Riesen-Haupt, Leon; Seryi, Andrei; Cruz Alaniz, Emilia

    2017-01-01

    One of the main challenges when designing final focus systems of particle accelerators is maximising the beam stay clear in the strong quadrupole magnets of the inner triplet. Moreover it is desirable to keep the quadrupoles in the triplet as short as possible for space and costs reasons but also to reduce chromaticity and simplify corrections schemes. An algorithm that explores the triplet parameter space to optimise both these aspects was written. It uses thin lenses as a first approximation and MADX for more precise calculations. In cooperation with radiation studies, this algorithm was then applied to design an alternative triplet for the final focus of the Future Circular Collider (FCC-hh).

  14. Searches for diboson resonances with ATLAS (VV, VH, HH, excl. diphoton resonance)

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00236292; The ATLAS collaboration

    2016-01-01

    This document summarises ATLAS searches for resonances decaying to diboson final states, VV , VH and HH, where V is either a W or a Z boson and H is the Standard Model Higgs boson. The results obtained are based on the full 2015 dataset corresponding to an integrated luminosity of 3.2 fb −1 . No discrepancies with respect to the Standard Model expectations are observed and thus 95% confidence level exclusion limits are set on the production cross section times branching ratios in a number of benchmark scenarios, including Heavy Vector Triplet, Randall-Sundrum Graviton and Extended Higgs sector models.

  15. Radiation Load Optimization in the Final Focus System of FCC-hh

    CERN Document Server

    Martin, Roman; Cerutti, Francesco; Tomás, Rogelio

    2016-01-01

    With a center-of-mass energy of up to 100 TeV, FCC-hh will produce highly energetic collision debris at the Interaction Point (IP). Protecting the final focus quadrupoles from this radiation is challenging, since the required amount of shielding placed inside the magnets will reduce the free aperture, thereby limiting the β^{*} reach and luminosity. Hence, radiation mitigation strategies that make best use of the available aperture are required. In this paper, we study the possibility to split the first quadrupole Q1 into two quadrupoles with individual apertures, in order to distribute the radiation load more evenly and reduce the peak dose.

  16. Sexually Transmitted Infections in Tehran

    Directory of Open Access Journals (Sweden)

    Maryam Afrakhteh

    2008-09-01

    Full Text Available Objective: Sexually transmitted infections (STIs remain a public health problem of major significance in most parts of the world. This study aimed to detect the most prevalent pathogens in patients with signs and symptoms of STI referring to a group of university clinics in Tehran.Materials and methods: In this cross-sectional study using randomized cluster sampling, 507 consecutive male and female patients presenting with signs and symptoms of STI referring to selected health care centers of Shahid Beheshti University were evaluated between May 2005 and May 2007. Diagnosis was made according to WHO criteria for signs and symptoms of STI in addition to microscopic study of genital discharges. Results: The most prevalent STI pathogens were Candida, Trichomona, Neisseria gonorrhoeae and Chlamydia with respective frequencies of 53.96%, 18.87%, 4.91% and 22.26% in women and 47.10%, 8.67%, 9.50% and 34.71% in men.Conclusion: Candida was detected in majority of cases. Chlamydia was the most prevalent STI in both sexes. Simple preventive care has crucial role in decreasing the frequency of STIs in society.

  17. Recessively transmitted predominantly motor neuropathies.

    Science.gov (United States)

    Parman, Yeşim; Battaloğlu, Esra

    2013-01-01

    Recessively transmitted predominantly motor neuropathies are rare and show a severe phenotype. They are frequently observed in populations with a high rate of consanguineous marriages. At least 15 genes and six loci have been found to be associated with autosomal recessive CMT (AR-CMT) and X-linked CMT (AR-CMTX) and also distal hereditary motor neuronopathy (AR-dHMN). These disorders are genetically heterogeneous but the clinical phenotype is relatively homogeneous. Distal muscle weakness and atrophy predominating in the lower extremities, diminished or absent deep tendon reflexes, distal sensory loss, and pes cavus are the main clinical features of this disorder with occasional cranial nerve involvement. Although genetic diagnosis of some of subtypes of AR-CMT are now available, rapid advances in the molecular genetics and cell biology show a great complexity. Animal models for the most common subtypes of human AR-CMT disease provide clues for understanding the pathogenesis of CMT and also help to reveal possible treatment strategies of inherited neuropathies. This chapter highlights the clinical features and the recent genetic and biological findings in these disorders based on the current classification.

  18. Zoonosis that is Transmitted Through Food

    OpenAIRE

    Tri Budhi Murdiati; Indrawati Sendow

    2006-01-01

    Zoonosis can be transmitted through a number of routes including food of animal products . Foodborne disease is a disease transmitted through food, while zoonosis is defined as a disease that can be transmitted from animal to man or vice versa . Then, if agent in foodborne disease is a zoonotic, it could be defined as foodborne zoonosis . The outbreaks of Bovine Spongioform Encephalopathy (BSE) followed by Avian influenza (AI) have caused increasing concern in the food safety of animal produc...

  19. USACE AIS Transmit Technical Support Summary Report

    Science.gov (United States)

    2014-09-01

    USACE AIS Transmit Technical Support Summary Report Distribution Statement A: Approved for public release; distribution is unlimited...September 2014 Report No. CD-D-09-15 USACE AIS Transmit Technical Support Summary Report ii UNCLAS//Public | CG-926 RDC | I. Gonin et al. Public...States Coast Guard Research & Development Center 1 Chelsea Street New London, CT 06320 USACE AIS Transmit Technical Support Summary Report

  20. DRILL BITS FOR HORIZONTAL WELLS

    Directory of Open Access Journals (Sweden)

    Paolo Macini

    1996-12-01

    Full Text Available This paper underlines the importance of the correct drill bit application in horizontal wells. Afler the analysis of the peculiarities of horizontal wells and drainholes drilling techniques, advantages and disadvantages of the application of both roller cone and fixed cutters drill bits have been discussed. Also, a review of the potential specific featuries useful for a correct drill bit selection in horizontal small diameter holes has been highlighted. Drill bits for these special applications, whose importance is quickly increasing nowadays, should be characterised by a design capable to deliver a good penetration rate low WOB, and, at the same time, be able to withstand high RPM without premature cutting structure failure and undergauge. Formation properties will also determine the cutting structure type and the eventual specific features for additional gauge and shoulder protection.

  1. EVIDENCE OF NON-THERMAL X-RAY EMISSION FROM HH 80

    Energy Technology Data Exchange (ETDEWEB)

    López-Santiago, J. [Instituto de Matemática Interdisciplinar, S. D. Astronomía y Geodesia, Facultad de Ciencias Matemáticas, Universidad Complutense de Madrid, E-28040 Madrid (Spain); Peri, C. S.; Benaglia, P. [Instituto Argentino de Radioastronomía (IAR), CCT La Plata (CONICET), C.C.5, 1894 Villa Elisa, Buenos Aires (Argentina); Bonito, R. [Dipartimento di Fisica e Chimica, Università di Palermo, Piazza del Parlamento 1, I-90134 Palermo (Italy); Miceli, M. [INAF-Osservatorio Astronomico di Palermo, Piazza del Parlamento 1, I-90134 Palermo (Italy); Albacete-Colombo, J. F. [Universidad Nacional del COMAHUE, Monseñor Esandi y Ayacucho, 8500 Viedma, Río Negro (Argentina); De Castro, E. [Dpto. de Astrofísica y CC. de la Atmósfera, Universidad Complutense de Madrid, E-28040 Madrid (Spain)

    2013-10-20

    Protostellar jets appear at all stages of star formation when the accretion process is still at work. Jets travel at velocities of hundreds of km s{sup –1}, creating strong shocks when interacting with the interstellar medium. Several cases of jets have been detected in X-rays, typically showing soft emission. For the first time, we report evidence of hard X-ray emission possibly related to non-thermal processes not explained by previous models of the post-shock emission predicted in the jet/ambient interaction scenario. HH 80 is located at the south head of the jet associated with the massive protostar IRAS 18162-2048. It shows soft and hard X-ray emission in regions that are spatially separated, with the soft X-ray emission region situated behind the region of hard X-ray emission. We propose a scenario for HH 80 where soft X-ray emission is associated with thermal processes from the interaction of the jet with denser ambient matter and hard X-ray emission is produced by synchrotron radiation at the front shock.

  2. Water and acetaldehyde in HH212: The first hot corino in Orion

    CERN Document Server

    Codella, C; Cabrit, S; Podio, L; Bachiller, R; Fontani, F; Gusdorf, A; Lefloch, B; Leurini, S; Tafalla, M

    2016-01-01

    Aims: Using the unprecedented combination of high resolution and sensitivity offered by ALMA, we aim to investigate whether and how hot corinos, circumstellar disks, and ejected gas are related in young solar-mass protostars. Methods: We observed CH$_3$CHO and deuterated water (HDO) high-excitation ($E_{\\rm u}$ up to 335 K) lines towards the Sun-like protostar HH212--MM1. Results: For the first time, we have obtained images of CH$_3$CHO and HDO emission in the inner $\\simeq$ 100 AU of HH212. The multifrequency line analysis allows us to contrain the density ($\\geq$ 10$^{7}$ cm$^{-3}$), temperature ($\\simeq$ 100 K), and CH$_3$CHO abundance ($\\simeq$ 0.2--2 $\\times$ 10$^{-9}$) of the emitting region. The HDO profile is asymmetric at low velocities ($\\leq$ 2 km s$^{-1}$ from $V_{\\rm sys}$). If the HDO line is optically thick, this points to an extremely small ($\\sim$ 20--40 AU) and dense ($\\ge$ 10$^{9}$ cm$^{-3}$) emitting region. Conclusions: We report the first detection of a hot corino in Orion. The HDO asymm...

  3. X-ray emission from protostellar jet HH 154: the first evidence of a diamond shock?

    CERN Document Server

    Bonito, R; Miceli, M; Peres, G; Micela, G; Favata, F

    2011-01-01

    X-ray emission from about ten protostellar jets has been discovered and it appears as a feature common to the most energetic jets. Although X-ray emission seems to originate from shocks internal to jets, the mechanism forming these shocks remains controversial. One of the best studied X-ray jet is HH 154 that has been observed by Chandra over a time base of about 10 years. We analyze the Chandra observations of HH 154 by investigating the evolution of its X-ray source. We show that the X-ray emission consists of a bright stationary component and a faint elongated component. We interpret the observations by developing a hydrodynamic model describing a protostellar jet originating from a nozzle and compare the X-ray emission synthesized from the model with the X-ray observations. The model takes into account the thermal conduction and radiative losses and shows that the jet/nozzle leads to the formation of a diamond shock at the nozzle exit. The shock is stationary over the period covered by our simulations and...

  4. Theory and observations of a jet in the _ orionis region: HH 444

    Directory of Open Access Journals (Sweden)

    L. López Martin

    2001-01-01

    Full Text Available El descubrimiento de un sistema de objetos Herbig{Haro eyectados por es- trellas j ovenes de baja masa en la regi on de Orionis (Reipurth et al. 1998 ha motivado a modelar la fotoionizaci on de un chorro neutro por una fuente externa. Presentamos espectros de rendija larga de alta resoluci on espectral de HH 444 y simulaciones num ericas para este objeto Herbig{Haro usando \\yguaz u", un c odigo 3D que incluye la din amica del gas y transferencia radiativa (Raga et al. 1999. Encontramos que es necesario incluir un per l de velocidad en el haz del chorro para explicar el diagrama posici on{velocidad del chorro HH. Tambi en necesitamos suponer un angulo de apertura no nulo en la base del chorro para explicar el de- crecimiento de la intensidad H con el aumento de la distancia a la fuente y una velocidad de eyecci on variable para reproducir los nudos que se observan a lo largo del chorro.

  5. Optimizing laboratory animal stress paradigms: The H-H* experimental design.

    Science.gov (United States)

    McCarty, Richard

    2017-01-01

    Major advances in behavioral neuroscience have been facilitated by the development of consistent and highly reproducible experimental paradigms that have been widely adopted. In contrast, many different experimental approaches have been employed to expose laboratory mice and rats to acute versus chronic intermittent stress. An argument is advanced in this review that more consistent approaches to the design of chronic intermittent stress experiments would provide greater reproducibility of results across laboratories and greater reliability relating to various neural, endocrine, immune, genetic, and behavioral adaptations. As an example, the H-H* experimental design incorporates control, homotypic (H), and heterotypic (H*) groups and allows for comparisons across groups, where each animal is exposed to the same stressor, but that stressor has vastly different biological and behavioral effects depending upon each animal's prior stress history. Implementation of the H-H* experimental paradigm makes possible a delineation of transcriptional changes and neural, endocrine, and immune pathways that are activated in precisely defined stressor contexts. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. GT1_abenz_1: Completing the OH ladder for HH 46

    Science.gov (United States)

    Benz, A.

    2010-03-01

    First results from PACS observations towards the low-mass protostar HH 46 show surprisingly bright OH lines. The hydroxyl radical OH plays important roles in the water and oxygen chemistry of star-forming regions and their cooling. Furthermore, the hydroxyl-to-water line ratios are interesting tracers for ionizing radiation. We propose a nearly complete observation of the OH ladder in low-mass star formation for the first time. Four OH transitions in the class I object HH 46 were detected by PACS. We propose complementary observations towards the source in PACS line spectroscopy mode at 53, 56, 65, 71, 96, 115 and 135 micron. We gain insight in the origin and formation of OH from the PACS spatial information. The completeness of the OH ladder allows a reliable determination of the OH abundance and thus constrains water chemistry and cooling contribution more precisely. In addition, we propose HIFI observations of the OH transition at 163.4 micron to resolve the three hyperfine components for the first time. This will allow to determine optical depths of OH and test the hypothesis of asymmetries between the two closely spaced triplets, as the second triplet will be observed within the HIFI priority science program. Note: This proposal is submitted under the Swiss part of the HIFI guaranteed time program; HIFI PI: Frank Helmich, HIFI Swiss Lead CoI: Arnold O. Benz

  7. 3-D Kinematics of the near-IR HH 223 outflow in L723

    CERN Document Server

    López, R; Estalella, R; Gómez, G; García-Lorenzo, B

    2014-01-01

    In this work we derive the full 3-D kinematics of the near-infrared outflow HH 223, located in the dark cloud Lynds 723 (L723), where a well-defined quadrupolar CO outflow is found. HH 223 appears projected onto the two lobes of the east-west CO outflow. The radio continuum source VLA 2, towards the centre of the CO outflow, harbours a multiple system of low-mass young stellar objects. One of the components has been proposed to be the exciting source of the east-west CO outflow. From the analisys of the kinematics, we get further evidence on the relationship between the near-infrared and CO outflows and on the location of their exciting source. The proper motions were derived using multi-epoch, narrow-band H$_2$ (2.122 $\\mu$m line) images. Radial velocities were derived from the 2.122 $\\mu$m line of the spectra. Because of the extended (~5 arcmin), S-shaped morphology of the target, the spectra were obtained with the Multi-Object-Spectroscopy (MOS) observing mode using the instrument LIRIS at the 4.2m William...

  8. 3D kinematics of the near-IR HH 223 outflow in L723

    Science.gov (United States)

    López, R.; Acosta-Pulido, J. A.; Estalella, R.; Gómez, G.; García-Lorenzo, B.

    2015-03-01

    In this work, we derive the full 3D kinematics of the near-infrared outflow HH 223, located in the dark cloud Lynds 723 (L723), where a well-defined quadrupolar CO outflow is found. HH 223 appears projected on to the two lobes of the east-west CO outflow. The radio continuum source VLA 2, towards the centre of the CO outflow, harbours a multiple system of low-mass young stellar objects. One of the components has been proposed to be the exciting source of the east-west CO outflow. From the analysis of the kinematics, we get further evidence on the relationship between the near-infrared and CO outflows and on the location of their exciting source. The proper motions were derived using multi-epoch, narrow-band H2 (2.122 μm line) images. Radial velocities were derived from the 2.122 μm line of the spectra. Because of the extended (˜5 arcmin), S-shaped morphology of the target, the spectra were obtained with the multi-object-spectroscopy (MOS) observing mode using the instrument Long-Slit Intermediate Resolution Infrared Spectrograph (LIRIS) at the 4.2 m William Herschel Telescope. To our knowledge, this work is the first time that MOS observing mode has been successfully used in the near-infrared range for an extended target.

  9. The time evolution of HH 1 from four epochs of HST images

    CERN Document Server

    Raga, A C; Esquivel, A; Bally, J

    2016-01-01

    We present an analysis of four epochs of H$\\alpha$ and [S II] $\\lambda\\lambda$ 6716/6731 HST images of HH 1. For determining proper motions we explore a new method based on analysis of spatially degraded images obtained convolving the images with wavelet functions of chosen widths. With this procedure we are able to generate maps of proper motion velocities along and across the outflow axis, as well as (angularly integrated) proper motion velocity distributions. From the four available epochs, we find the time evolution of the velocities, intensities and spatial distribution of the line emission. We find that over the last two decades HH 1 shows a clear acceleration. Also, the H$\\alpha$ and [S II] intensities have first dropped, and then recovered in the more recent (2014) images. Finally, we show a comparison between the two available HST epochs of [O III] $\\lambda$ 5007 (1994 and 2014), in which we see a clear drop in the value of the [O III]/H$\\alpha$ ratio.

  10. 20 years of cosmic muons research performed in IFIN-HH

    Energy Technology Data Exchange (ETDEWEB)

    Mitrica, Bogdan [Horia Hulubei National Institute of Physics and Nuclear Engineering - IFIN HH, Bucharest, P.O.B.MG-6 (Romania)

    2012-11-20

    During the last two decades a modern direction in particle physics research has been developed in IFIN-HH Bucharest, Romania. The history started with the WILLI detector built in IFIN-HH Bucharest in collaboration with KIT Karlsruhe (formerly Forschungszentrum Karlsruhe). The detector was designed for measurements of the low energy muon charge ratio (< 1GeV) based on a delayed coincidence method, measuring the decay time of the muons stopped in the detector: the positive muons decay freely, but the negative muons are captured in the atom thus creating muonic atoms and decay depending on the nature of the host atom. In a first configuration, the WILLI detector was placed in a fixed position for measuring vertical muons. Further WILLI has been transformed in a rotatable device which allows directional measurements of muon charge ratio and muon flux. The results exhibit a pronounced azimuthal asymmetry (East-West effect) due to the different in fluence of the geomagnetic field on the trajectories of positive and negative muons in air. In parallel, flux measurement, taking into account muon events with nergies > 0.4GeV, show a diurnal modulation of the muon flux. The analysis of the muon events for energies < 0.6GeV reveals an aperiodic variation of the muon flux. A new detection system performing coincidence measurements between the WILLI calorimeter and a small array of 12 scintillators plates has been installed in IFIN-HH starting from the autumn of 2010. The aim of the system is to investigate muon charge ratio from individual EAS by using the mini-array as trigger for the WILLI calorimeter. Such experimental studies could provide detailed information on hadronic interaction models and primary cosmic ray composition at energies around 10{sup 15}eV. Simulation studies and preliminary experimental tests, regarding the performances of the mini-array, have been performed using H and Fe primaries, with energies in a range 10{sup 13}eV - 10{sup 15}eV. The results show

  11. Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination.

    Directory of Open Access Journals (Sweden)

    Tongchao Li

    2016-05-01

    Full Text Available Hedgehog (Hh signaling regulates multiple aspects of metazoan development and tissue homeostasis, and is constitutively active in numerous cancers. We identified Ubr3, an E3 ubiquitin ligase, as a novel, positive regulator of Hh signaling in Drosophila and vertebrates. Hh signaling regulates the Ubr3-mediated poly-ubiquitination and degradation of Cos2, a central component of Hh signaling. In developing Drosophila eye discs, loss of ubr3 leads to a delayed differentiation of photoreceptors and a reduction in Hh signaling. In zebrafish, loss of Ubr3 causes a decrease in Shh signaling in the developing eyes, somites, and sensory neurons. However, not all tissues that require Hh signaling are affected in zebrafish. Mouse UBR3 poly-ubiquitinates Kif7, the mammalian homologue of Cos2. Finally, loss of UBR3 up-regulates Kif7 protein levels and decreases Hh signaling in cultured cells. In summary, our work identifies Ubr3 as a novel, evolutionarily conserved modulator of Hh signaling that boosts Hh in some tissues.

  12. 177Lu-DOTA-HH1, a Novel Anti-CD37 Radio-Immunoconjugate: A Study of Toxicity in Nude Mice

    Science.gov (United States)

    Repetto-Llamazares, Ada H. V.; Larsen, Roy H.; Giusti, Anna Maria; Riccardi, Elena; Bruland, Øyvind S.; Selbo, Pål Kristian; Dahle, Jostein

    2014-01-01

    Background CD37 is an internalizing B-cell antigen expressed on Non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukemia cells (CLL). The anti-CD37 monoclonal antibody HH1 was conjugated to the bifunctional chelator p-SCN-Bn-DOTA and labelled with the beta-particle emitting radionuclide 177Lu creating the radio-immunoconjugate (RIC) 177Lu-DOTA-HH1 (177Lu-HH1, trade name Betalutin). The present toxicity study was performed prior to initiation of clinical studieswith 177Lu-HH1. Methodology/Principal Findings Nude mice with or without tumor xenografts were treated with 50 to 1000 MBq/kg 177Lu- HH1 and followed for clinical signs of toxicity up to ten months. Acute, life threatening bone marrow toxicity was observed in animals receiving 800 and 1000 MBq/kg 177Lu-HH1. Significant changes in serum concentrations of liver enzymes were evident for treatment with 1000 MBq/kg 177Lu-HH1. Lymphoid depletion, liver necrosis and atrophy, and interstitial cell hyperplasia of the ovaries were also observed for mice in this dose group. Conclusions/Significance 177Lu-DOTA-HH1 was well tolerated at dosages about 10 times above those considered relevant for radioimmunotherapy in patients with B-cell derived malignancies.The toxicity profile was as expected for RICs. Our experimental results have paved the way for clinical evaluation of 177Lu-HH1 in NHL patients. PMID:25068508

  13. 177Lu-DOTA-HH1, a novel anti-CD37 radio-immunoconjugate: a study of toxicity in nude mice.

    Directory of Open Access Journals (Sweden)

    Ada H V Repetto-Llamazares

    Full Text Available CD37 is an internalizing B-cell antigen expressed on Non-Hodgkin lymphoma (NHL and chronic lymphocytic leukemia cells (CLL. The anti-CD37 monoclonal antibody HH1 was conjugated to the bifunctional chelator p-SCN-Bn-DOTA and labelled with the beta-particle emitting radionuclide 177Lu creating the radio-immunoconjugate (RIC 177Lu-DOTA-HH1 (177Lu-HH1, trade name Betalutin. The present toxicity study was performed prior to initiation of clinical studies with 177Lu-HH1.Nude mice with or without tumor xenografts were treated with 50 to 1000 MBq/kg 177Lu- HH1 and followed for clinical signs of toxicity up to ten months. Acute, life threatening bone marrow toxicity was observed in animals receiving 800 and 1000 MBq/kg 177Lu-HH1. Significant changes in serum concentrations of liver enzymes were evident for treatment with 1000 MBq/kg 177Lu-HH1. Lymphoid depletion, liver necrosis and atrophy, and interstitial cell hyperplasia of the ovaries were also observed for mice in this dose group.177Lu-DOTA-HH1 was well tolerated at dosages about 10 times above those considered relevant for radioimmunotherapy in patients with B-cell derived malignancies.The toxicity profile was as expected for RICs. Our experimental results have paved the way for clinical evaluation of 177Lu-HH1 in NHL patients.

  14. Horizontal Diplopia Following Upper Blepharoplasty

    Directory of Open Access Journals (Sweden)

    Tomás Ortiz-Basso

    2014-09-01

    Full Text Available Diplopia is an infrequent complication after blepharoplasty. Most of the cases are in its vertical form due to trauma of the extraocular muscles. In this article, we present a case of horizontal diplopia following cosmetic upper blepharoplasty; we review the literature on this unexpected complication and offer some recommendations to avoid it.

  15. VARIABLE JETS WITH NON-TOP HAT EJECTION CROSS SECTIONS: A MODEL FOR THE KNOTS OF THE HH 34 JET

    Directory of Open Access Journals (Sweden)

    A. C. Raga

    2011-01-01

    Full Text Available Calculamos modelos axisimétricos, con una variación sinusoidal (de un modo y un perfil de sección recta inicial de velocidad. Encontramos que para cocientes de velocidad borde a centro decrecientes, uno obtiene superficies de trabajo con choques de proa con alas progresivamente más extendidas. Estas alas producen emisión de [S II] que parcialmente llena las regiones entre los nudos en los mapas de emisión predichos. Luego calculamos modelos de 3 modos (con parámetros apropiados para el chorro HH 34, y comparamos los mapas de emisión predichos con imágenes del archivo del HST de HH 34. Encontramos que un modelo con cociente de velocidades borde a centro moderado produce estructuras de nudos con morfologías y variabilidades temporales muy parecidas a las observadas en HH 34.

  16. The jet/counterjet IR symmetry of HH34 and the size of the jet formation region

    CERN Document Server

    Raga, A C; Lora, V; Stapelfeldt, K R; Carey, S J

    2011-01-01

    We present a new Spitzer IRAC images of the HH 34 outflow. These are the first images that detect both the knots along the southern jet and the northern counterjet (the counterjet knots were only detected previously in a long slit spectrum). This result removes the problem of the apparent coexistence of a large scale symmetry (at distances of up to approx.1 pc) and a complete lack of symmetry close to the source (at distances of approx. 1.e+17 cm) for this outflow. We present a quantitative evaluation of the newly found symmetry between the HH 34 jet and counterjet, and show that the observed degree of symmetry implies that the jet production region has a characteristic size <2.8 AU. This is the strongest constraint yet derived for the size of the region in which HH jets are produced.

  17. Horizontal capacity of skirted circular shallow footings on sand

    Directory of Open Access Journals (Sweden)

    Amr Z. El Wakil

    2010-12-01

    Full Text Available Shallow footings are subjected to lateral forces induced by earthquake movements, wind loads, water wave pressure, lateral earth pressure, and transmitting power cables. In some structures such as water front structure, earth retaining structure and transmitting power structures, the lateral forces acting on the footings may be dominant. There has been little work studying the performance of skirted footings subjected to lateral loads. Twelve loading tests were performed on small scale circular skirted footing to shed some light on the performance of skirted footings when subjected to lateral loads. The effects of skirt length and the relative density of sand on the performance of the footing were investigated through laboratory testing program. Also a comparative experimental study between ultimate horizontal loads attained by skirted and unskirted footings with the same properties was conducted. From the accomplished laboratory tests it was found that the skirts changed the failure mode of circular shallow footings from sliding mechanism into rotational mechanism. Also the skirts attached to footings increased appreciably the ultimate horizontal capacity of shallow footings.

  18. Techniques for transmitting digital data on the Spacelab's analog video channel

    Science.gov (United States)

    Smith, Dean L.; Hanby, Walter D.

    1993-01-01

    A study was made of various techniques for transmitting digital data over a composite video channel. Transmitting data from experiments on the Space Shuttle Orbiter over a video channel is attractive since extra channel capacity is needed. Broadcast television telecommunications schemes and other techniques described in the literature were reviewed and compared. PSK (Phase Shift Keying), MPSK (m-ary PSK), or PAM (Pulse Amplitude Modulation) can be transmitted on visible lines of a frame, unassigned lines of the VBI (Vertical Blanking Interval), or during the HBI (Horizontal Blanking Interval). All three modulation techniques can be attractive under the proper conditions. However, PAM on visible lines or during the VBI should be relatively easy to implement, provide adequate average data rates, and give acceptable BERs (Bit Error Rates).

  19. THE COUNTERJET OF HH 30: NEW LIGHT ON ITS BINARY DRIVING SOURCE

    Energy Technology Data Exchange (ETDEWEB)

    Estalella, Robert; Lopez, Rosario; Riera, Angels [Departament d' Astronomia i Meteorologia, Institut de Ciencies del Cosmos (ICC), Universitat de Barcelona (IEEC-UB), Marti i Franques 1, E-08028 Barcelona (Spain); Anglada, Guillem; Carrasco-Gonzalez, Carlos [Instituto de Astrofisica de Andalucia, CSIC, Glorieta de la Astronomia s/n, E-18008 Granada (Spain); Gomez, Gabriel, E-mail: robert.estalella@am.ub.es, E-mail: rosario.lopez@am.ub.es, E-mail: guillem@iaa.es, E-mail: ggv@iac.es, E-mail: gabriel.gomez@gtc.iac.es, E-mail: angels.riera@upc.edu, E-mail: carrasco@mpifr-bonn.mpg.de [Instituto de Astrofisica de Canarias, E-38200 La Laguna, Tenerife (Spain)

    2012-08-15

    We present new [S II] images of the Herbig-Haro (HH) 30 jet and counterjet observed in 2006, 2007, and 2010 that, combined with previous data, allowed us to measure with improved accuracy the positions and proper motions of the jet and counterjet knots. Our results show that the motion of the knots is essentially ballistic, with the exception of the farthest knots, which trace the large-scale 'C'-shape bending of the jet. The observed bending of the jet can be produced by a relative motion of the HH 30 star with respect to its surrounding environment, caused either by a possible proper motion of the HH 30 star, or by the entrainment of environment gas by the red lobe of the nearby L1551-IRS5 outflow. Alternatively, the bending can be produced by the stellar wind from a nearby classical T Tauri star, identified in the Two Micron All Sky Survey catalog as J04314418+181047. The proper motion velocities of the knots of the counterjet show more variations than those of the jet. In particular, we identify two knots of the counterjet that have the same kinematic age but whose velocities differ by almost a factor of two. Thus, it appears from our observations that counterjet knots launched simultaneously can be ejected with very different velocities. We confirm that the observed wiggling of the jet and counterjet arises from the orbital motion of the jet source in a binary system. Precession, if present at all, is of secondary importance in shaping the jet. We derive an orbital period of {tau}{sub o} = 114 {+-} 2 yr and a mass function of m{mu}{sup 3}{sub c} = 0.014 {+-} 0.006 M{sub Sun }. For a mass of the system of m = 0.45 {+-} 0.04 M{sub Sun} (the value inferred from observations of the CO kinematics of the disk), we obtain a mass of m{sub j} = 0.31 {+-} 0.04 M{sub Sun} for the jet source, a mass of m{sub c} = 0.14 {+-} 0.03 M{sub Sun} for the companion, and a binary separation of a = 18.0 {+-} 0.6 AU. This binary separation coincides with the value required

  20. Parasitic diseases in humans transmitted by vectors.

    Science.gov (United States)

    Cholewiński, Marcin; Derda, Monika; Hadaś, Edward

    2015-01-01

    Despite the considerable progress of medicine, parasitic diseases still pose a great threat to human health and life. Among parasitic diseases, those transmitted by vectors, mainly arthropods, play a particular role. These diseases occur most frequently in the poorest countries and affect a vast part of the human population. They include malaria, babesiosis, trypanosomiasis, leishmaniasis and filariasis. This study presents those vector-transmitted diseases that are responsible for the greatest incidence and mortality of people on a global scale. Attention is focused primarily on diseases transmitted by mosquitoes, flies, Hemiptera and ticks.

  1. Non linear field correction effects on the dynamic aperture of the FCC-hh

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00361058; Seryi, Andrei; Maclean, Ewen Hamish; Martin, Roman; Tomas Garcia, Rogelio

    2017-01-01

    The Future Circular Collider (FCC) design study aims to develop the designs of possible circular colliders in the post LHC era. In particular the FCC-hh will aim to produce proton-proton collisions at a center of mass energy of 100 TeV. Given the large beta functions and integrated length of the quadrupoles of the final focus triplet the effect of systematic and random non linear errors in the magnets are expected to have a severe impact on the stability of the beam. Following the experience on the HL-LHC this work explores the implementation of non-linear correctors to minimize the resonance driving terms arising from the errors of the triplet. Dynamic aperture studies are then performed to study the impact of this correction.

  2. Physics at the FCC-hh, a 100 TeV pp collider

    CERN Document Server

    2017-01-01

    A 100 TeV pp collider is under consideration, by the high-energy physics community, as an important step for the future development of our field, following the completion of the LHC and High-luminosity LHC physics programmes. In particular, CERN is considering 100 TeV pp collisions as the key target of a Future Circular Collider facility, built around a 100 km tunnel and designed to deliver pp, e+e- and ep collisions, in addition to a programme with heavy ion beams and with the injector complex. CERN is coordinating an international study tasked with the completion, by the end of 2018, of a Conceptual Design Report (CDR) for this facility. This document presents the first results of the assessment of the physics potential of the hadronic part of this research programme (FCC-hh).

  3. Proton cross-talk and losses in the dispersion suppressor regions at the FCC-hh

    CERN Document Server

    Rafique, Haroon; Krainer, Alexander; Langner, Andy Sven; Abelleira, Jose

    2017-01-01

    Protons that collide at the interaction points of the FCC-hh may contribute to the background in the subsequent detector. Due to the high luminosity of the proton beams this may be of concern. Using DPMJET-III to model 50 TeV proton-proton collisions, tracking studies have been performed with PTC and MERLIN in order to gauge the elastic and inelastic proton cross-talk. High arc losses, particularly in the dispersion suppressor regions, have been revealed. These losses originate mainly from particles with a momentum deviation, either from interaction with a primary collimator in the betatron cleaning insertion, or from the proton-proton collisions. This issue can be mitigated by introducing additional collimators in the dispersion suppressor region. The specific design, lattice integration, and the effect of these collimators on cross-talk is assessed.

  4. ATLAS Searches for VH, HH, VV, V+$\\gamma$/$\\gamma\\gamma$ Resonances

    CERN Document Server

    Biesuz, Nicolo Vladi; The ATLAS collaboration

    2017-01-01

    The discovery of a Higgs boson at the Large Hadron Collider motivates searches for physics beyond the Standard Model in channels involving coupling to the Higgs boson. A search for massive resonances decaying into couples of bosons is described. The considered final states are: $HH$, $VH$, $VV$, $V\\gamma$ and $\\gamma\\gamma$ with $V$ indicating either the $W$ or the $Z$ boson. Final states with different number of leptons or photons and where, in many cases, at least one Higgs decays into a b-quark pair are studied using different jet reconstruction techniques which allow to optimize the signal acceptance for low or Higgs boson transverse momentum. The most recent diboson resonance searches using LHC Run 2 data are described.

  5. Evidence for CP violation in time-integrated $D^0 \\rightarrow h^-h^+$ decay rates

    CERN Document Server

    Aaij, R; Adeva, B; Adinolfi, M; Adrover, C; Affolder, A; Ajaltouni, Z; Albrecht, J; Alessio, F; Alexander, M; Alkhazov, G; Alvarez Cartelle, P; Alves, A A; Amato, S; Amhis, Y; Anderson, J; Appleby, R B; Aquines Gutierrez, O; Archilli, F; Arrabito, L; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Bachmann, S; Back, J J; Bailey, D S; Balagura, V; Baldini, W; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Bates, A; Bauer, C; Bauer, Th; Bay, A; Bediaga, I; Belogurov, S; Belous, K; Belyaev, I; Ben-Haim, E; Benayoun, M; Bencivenni, G; Benson, S; Benton, J; Bernet, R; Bettler, M-O; van Beuzekom, M; Bien, A; Bifani, S; Bird, T; Bizzeti, A; Bjørnstad, P M; Blake, T; Blanc, F; Blanks, C; Blouw, J; Blusk, S; Bobrov, A; Bocci, V; Bondar, A; Bondar, N; Bonivento, W; Borghi, S; Borgia, A; Bowcock, T J V; Bozzi, C; Brambach, T; van den Brand, J; Bressieux, J; Brett, D; Britsch, M; Britton, T; Brook, N H; Brown, H; Büchler-Germann, A; Burducea, I; Bursche, A; Buytaert, J; Cadeddu, S; Callot, O; Calvi, M; Calvo Gomez, M; Camboni, A; Campana, P; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carson, L; Carvalho Akiba, K; Casse, G; Cattaneo, M; Cauet, Ch; Charles, M; Charpentier, Ph; Chiapolini, N; Ciba, K; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Coca, C; Coco, V; Cogan, J; Collins, P; Comerma-Montells, A; Constantin, F; Contu, A; Cook, A; Coombes, M; Corti, G; Cowan, G A; Currie, R; D'Ambrosio, C; David, P; David, P N Y; De Bonis, I; De Capua, S; De Cian, M; De Lorenzi, F; De Miranda, J M; De Paula, L; De Simone, P; Decamp, D; Deckenhoff, M; Degaudenzi, H; Del Buono, L; Deplano, C; Derkach, D; Deschamps, O; Dettori, F; Dickens, J; Dijkstra, H; Diniz Batista, P; Domingo Bonal, F; Donleavy, S; Dordei, F; Dosil Suárez, A; Dossett, D; Dovbnya, A; Dupertuis, F; Dzhelyadin, R; Dziurda, A; Easo, S; Egede, U; Egorychev, V; Eidelman, S; van Eijk, D; Eisele, F; Eisenhardt, S; Ekelhof, R; Eklund, L; Elsasser, Ch; Elsby, D; Esperante Pereira, D; Estève, L; Falabella, A; Fanchini, E; Färber, C; Fardell, G; Farinelli, C; Farry, S; Fave, V; Fernandez Albor, V; Ferro-Luzzi, M; Filippov, S; Fitzpatrick, C; Fontana, M; Fontanelli, F; Forty, R; Frank, M; Frei, C; Frosini, M; Furcas, S; Gallas Torreira, A; Galli, D; Gandelman, M; Gandini, P; Gao, Y; Garnier, J-C; Garofoli, J; Garra Tico, J; Garrido, L; Gascon, D; Gaspar, C; Gauvin, N; Gersabeck, M; Gershon, T; Ghez, Ph; Gibson, V; Gligorov, V V; Göbel, C; Golubkov, D; Golutvin, A; Gomes, A; Gordon, H; Grabalosa Gándara, M; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graziani, G; Grecu, A; Greening, E; Gregson, S; Gui, B; Gushchin, E; Guz, Yu; Gys, T; Haefeli, G; Haen, C; Haines, S C; Hampson, T; Hansmann-Menzemer, S; Harji, R; Harnew, N; Harrison, J; Harrison, P F; Hartmann, T; He, J; Heijne, V; Hennessy, K; Henrard, P; Hernando Morata, J A; van Herwijnen, E; Hicks, E; Holubyev, K; Hopchev, P; Hulsbergen, W; Hunt, P; Huse, T; Huston, R S; Hutchcroft, D; Hynds, D; Iakovenko, V; Ilten, P; Imong, J; Jacobsson, R; Jaeger, A; Jahjah Hussein, M; Jans, E; Jansen, F; Jaton, P; Jean-Marie, B; Jing, F; John, M; Johnson, D; Jones, C R; Jost, B; Kaballo, M; Kandybei, S; Karacson, M; Karbach, T M; Keaveney, J; Kenyon, I R; Kerzel, U; Ketel, T; Keune, A; Khanji, B; Kim, Y M; Knecht, M; Koopman, R; Koppenburg, P; Kozlinskiy, A; Kravchuk, L; Kreplin, K; Kreps, M; Krocker, G; Krokovny, P; Kruse, F; Kruzelecki, K; Kucharczyk, M; Kvaratskheliya, T; La Thi, V N; Lacarrere, D; Lafferty, G; Lai, A; Lambert, D; Lambert, R W; Lanciotti, E; Lanfranchi, G; Langenbruch, C; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Lees, J-P; Lefèvre, R; Leflat, A; Lefrançois, J; Leroy, O; Lesiak, T; Li, L; Li Gioi, L; Lieng, M; Liles, M; Lindner, R; Linn, C; Liu, B; Liu, G; von Loeben, J; Lopes, J H; Lopez Asamar, E; Lopez-March, N; Lu, H; Luisier, J; Mac Raighne, A; Machefert, F; Machikhiliyan, I V; Maciuc, F; Maev, O; Magnin, J; Malde, S; Mamunur, R M D; Manca, G; Mancinelli, G; Mangiafave, N; Marconi, U; Märki, R; Marks, J; Martellotti, G; Martens, A; Martin, L; Martín Sánchez, A; Martinez Santos, D; Massafferri, A; Mathe, Z; Matteuzzi, C; Matveev, M; Maurice, E; Maynard, B; Mazurov, A; McGregor, G; McNulty, R; Meissner, M; Merk, M; Merkel, J; Messi, R; Miglioranzi, S; Milanes, D A; Minard, M-N; Molina Rodriguez, J; Monteil, S; Moran, D; Morawski, P; Mountain, R; Mous, I; Muheim, F; Müller, K; Muresan, R; Muryn, B; Muster, B; Musy, M; Mylroie-Smith, J; Naik, P; Nakada, T; Nandakumar, R; Nasteva, I; Nedos, M; Needham, M; Neufeld, N; Nguyen-Mau, C; Nicol, M; Niess, V; Nikitin, N; Nomerotski, A; Novoselov, A; Oblakowska-Mucha, A; Obraztsov, V; Oggero, S; Ogilvy, S; Okhrimenko, O; Oldeman, R; Orlandea, M; Otalorav Goicochea, J M; Owen, P; Pal, K; Palacios, J; Palano, A; Palutan, M; Panman, J; Papanestis, A; Pappagallo, M; Parkes, C; Parkinson, C J; Passaleva, G; Patel, G D; Patel, M; Paterson, S K; Patrick, G N; Patrignani, C; Pavel-Nicorescu, C; Pazos Alvarez, A; Pellegrino, A; Penso, G; Pepe Altarelli, M; Perazzini, S; Perego, D L; Perez Trigo, E; Pérez-Calero Yzquierdo, A; Perret, P; Perrin-Terrin, M; Pessina, G; Petrella, A; Petrolini, A; Phan, A; Picatoste Olloqui, E; Pie Valls, B; Pietrzyk, B; Pilař, T; Pinci, D; Plackett, R; Playfer, S; Plo Casasus, M; Polok, G; Poluektov, A; Polycarpo, E; Popov, D; Popovici, B; Potterat, C; Powell, A; Prisciandaro, J; Pugatch, V; Puig Navarro, A; Qian, W; Rademacker, J H; Rakotomiaramanana, B; Rangel, M S; Raniuk, I; Raven, G; Redford, S; Reid, M M; dos Reis, A C; Ricciardi, S; Rinnert, K; Roa Romero, D A; Robbe, P; Rodrigues, E; Rodrigues, F; Rodriguez Perez, P; Rogers, G J; Roiser, S; Romanovsky, V; Rosello, M; Rouvinet, J; Ruf, T; Ruiz, H; Sabatino, G; Saborido Silva, J J; Sagidova, N; Sail, P; Saitta, B; Salzmann, C; Sannino, M; Santacesaria, R; Santamarina Rios, C; Santinelli, R; Santovetti, E; Sapunov, M; Sarti, A; Satriano, C; Satta, A; Savrie, M; Savrina, D; Schaack, P; Schiller, M; Schleich, S; Schlupp, M; Schmelling, M; Schmidt, B; Schneider, O; Schopper, A; Schune, M-H; Schwemmer, R; Sciascia, B; Sciubba, A; Seco, M; Semennikov, A; Senderowska, K; Sepp, I; Serra, N; Serrano, J; Seyfert, P; Shapkin, M; Shapoval, I; Shatalov, P; Shcheglov, Y; Shears, T; Shekhtman, L; Shevchenko, O; Shevchenko, V; Shires, A; Silva Coutinho, R; Skwarnicki, T; Smith, A C; Smith, N A; Smith, E; Sobczak, K; Soler, F J P; Solomin, A; Soomro, F; Souza De Paula, B; Spaan, B; Sparkes, A; Spradlin, P; Stagni, F; Stahl, S; Steinkamp, O; Stoica, S; Stone, S; Storaci, B; Straticiuc, M; Straumann, U; Subbiah, V K; Swientek, S; Szczekowski, M; Szczypka, P; Szumlak, T; T'Jampens, S; Teodorescu, E; Teubert, F; Thomas, C; Thomas, E; van Tilburg, J; Tisserand, V; Tobin, M; Topp-Joergensen, S; Torr, N; Tournefier, E; Tran, M T; Tsaregorodtsev, A; Tuning, N; Ubeda Garcia, M; Ukleja, A; Urquijo, P; Uwer, U; Vagnoni, V; Valenti, G; Vazquez Gomez, R; Vazquez Regueiro, P; Vecchi, S; Velthuis, J J; Veltri, M; Viaud, B; Videau, I; Vilasis-Cardona, X; Visniakov, J; Vollhardt, A; Volyanskyy, D; Voong, D; Vorobyev, A; Voss, H; Wandernoth, S; Wang, J; Ward, D R; Watson, N K; Webber, A D; Websdale, D; Whitehead, M; Wiedner, D; Wiggers, L; Wilkinson, G; Williams, M P; Williams, M; Wilson, F F; Wishahi, J; Witek, M; Witzeling, W; Wotton, S A; Wyllie, K; Xie, Y; Xing, F; Xing, Z; Yang, Z; Young, R; Yushchenko, O; Zavertyaev, M; Zhang, F; Zhang, L; Zhang, W C; Zhang, Y; Zhelezov, A; Zhong, L; Zverev, E; Zvyagin, A

    2012-01-01

    A search for time-integrated $CP$ violation in $D^0 \\rightarrow h^-h^+$ ($h=K$, $\\pi$) decays is presented using 0.62~fb$^{-1}$ of data collected by LHCb in 2011. The flavor of the charm meson is determined by the charge of the slow pion in the $D^{*+} \\rightarrow D^0 \\pi^+$ and $D^{*-} \\rightarrow \\overline{D}^0 \\pi^-$ decay chains. The difference in $CP$ asymmetry between $D^0 \\rightarrow K^- K^+$ and $D^0 \\rightarrow \\pi^- \\pi^+$, $\\Delta A_{CP} \\equiv A_{CP}(K^-K^+) \\, - \\, A_{CP}(\\pi^-\\pi^+)$, is measured to be $\\left[ -0.82 \\pm 0.21 (\\mathrm{stat.}) \\pm 0.11 (\\mathrm{syst.}) \\right]\\%$. This differs from the hypothesis of $CP$ conservation by $3.5$ standard deviations.

  6. LINEAR FREE VIBRATIONS OF FGCNTRC H-H BEAMS USING SLENDER BEAM THEORY

    Directory of Open Access Journals (Sweden)

    KRISHNA CHAITANYA VULCHI

    2013-09-01

    Full Text Available This thesis investigates the linear free vibrations of functionally graded Carbon Nano-tube reinforced Composite (FG-CNTRC beams using Slender (Euler-Bernoulli’s beam theory. The material properties of FG-CNTRCs are assumed to be graded in the thickness direction and estimated through the rule of mixture. The Ritz method is employed to derive the governing Eigen value equation which is then solved by a direct iterative method to obtain the linear frequencies of FG-CNTRC beams with H-H Supports. A detailed parametric study is conducted to study the influences of Nanotube volume fraction, vibration amplitude, and slenderness ratio on the linear free vibration characteristics of FG-CNTRC beams.

  7. Dissecting a Molecular Shock: Spatially Resolved H2 Line Ratios Across the HH7 Bow Shock

    Science.gov (United States)

    Pike, Rosemary E.; Geballe, Thomas R.; Burton, Michael G.; Chrysostomou, Antonio; Brand, Peter

    2015-01-01

    We report on a detailed study of the physics of molecular shocks using Gemini NIFS (Near-Infrared Field Spectrometer) K-band spectra of a 3.'2 x 2.'9 region near the tip of the HH7 bow shock. The IFU data have an angular resolution of 0.3", much higher resolution then in any previous study of a molecular shock, and a velocity resolution of 60 km/s. We have detected 20 H2 emission lines with upper state energies as high as 28,000 K, and 6 additional unidentified lines which share the same bow shock morphology as the H2. We use excitation temperatures derived from line pairs measured in 0.15' x 0.15' bins to attempt to constrain the shock type and distinguish between low velocity jump shocks, continuous shocks, and dissociative shocks in which the H2 line emission arises from newly reformed H2.

  8. Outflow Entrainment and Feedback: A Case Study with HH46/47 Molecular Outflow

    Science.gov (United States)

    Zhang, Yichen; Arce, H.; Mardones, D.; Cabrit, S.

    2017-06-01

    Our ALMA multi-cycle multi-band observations of HH46/47 outflow show co-existence of entrainment by both wide-angle wind and jet bow-shock and this outflow is at a moment that the former has just become dominant. The estimated outflow mass and strength suggest that it has already strongly affected the core-to-star efficiency to 1/3 at this early stage. The zoom-in observation also reveals multiple wide outflowing shells with positions and shapes smoothly changing over a wide range of velocity, which may be an evidence of episodic eruption not only in jet but also in the wide-angle wind.

  9. Probing Charged Higgs Boson Couplings at the FCC-hh Collider

    CERN Document Server

    Cakir, I T; Saygin, H; Senol, A; Cakir, O

    2015-01-01

    Many of the new physics models predicts a light Higgs boson similar to the Higgs boson of the Standard Model (SM) and also extra scalar bosons. Beyond the search channels for a SM Higgs boson, the future collider experiments will explore additional channels that are specific to extended Higgs sectors. We study the charged Higgs boson production within the framework of two Higgs doublet models (THDM) in the proton-proton collisions at the FCC-hh collider. With an integrated luminosity of 500 fb$^{-1}$ at very high energy frontier, we obtain a significant coverage of the parameter space and distinguish the charged Higgs-top-bottom interaction within the THDM or other new physics models with charged Higgs boson mass up to 1 TeV.

  10. Horizontally oriented plates in clouds

    CERN Document Server

    Bréon, François-Marie

    2011-01-01

    Horizontally oriented plates in clouds generate a sharp specular reflectance signal in the glint direction, often referred to as "subsun". This signal (amplitude and width) may be used to analyze the relative area fraction of oriented plates in the cloud top layer and their characteristic tilt angle to the horizontal. We make use of spaceborne measurements from the POLDER instrument to provide a statistical analysis of these parameters. More than half of the clouds show a detectable maximum reflectance in the glint direction, although this maximum may be rather faint. The typical effective fraction (area weighted) of oriented plates in clouds lies between 10-3 and 10-2. For those oriented plates, the characteristic tilt angle is less than 1 degree in most cases. These low fractions imply that the impact of oriented plates on the cloud albedo is insignificant. The largest proportion of clouds with horizontally oriented plates is found in the range 500-700 hPa, in agreement with typical in situ observation of p...

  11. Partial Horizontal Laryngectomy and Epiglottiplasty

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    In order to evaluate the availability of the lateral horizontal laryngectomy and anaplasty of epiglottis to treat somepatients with specific supraglottic carcinomas and hypopharyngeal carcinomas, 17 cases of laryngeal and hypopharyngeal carcinomas were retrospectively analyzed, whose tumors were located at the lateral margin of epiglottis, aryepiglottic fold, medial wall of piriformfossa and were treated by the lateral horizontal laryngectomy and anaplasty of epiglottis. The results showed that all cases took food by mouth in postoperative 9-14 days and subjected to decannulation in postoperative 9-15 days. Three cases had postoperative hoarse voice. The free-disease survival rate of 3 years was 71.4 % in 14 cases followed up after the first surgical therapy, and the overall free-disease survival rate of 3 years was 85.7 % after the second surgical therapy. It was concluded that the manipulations of the lateral horizontal laryngectomy and epiglottiplasty were simple. It could alleviate the postoperative symptoms of aspiration and bucking remarkably and shorten their postoperative recovery time, yet does not lower the survival rate of patients if laryngocarcinoma or hypopharyngeal carcinoma cases were properly selected.

  12. Fabry-perot kinematics of hh 202-204 in the orion nebula: are they part of a big bipolar outflow?

    Directory of Open Access Journals (Sweden)

    M. Rosado

    2002-01-01

    Full Text Available Se presenta un estudio cinem atico de los objetos HH 202, 203 y 204 usando mapas de velocidad Fabry-Perot en H y [N II]. En el caso de HH 202 se encuentran nebulosidades que podr an estar asociadas a este objeto o bien, dada sus altas velocidades (superiores a 100 km s

  13. A Mid-Infrared Spitzer Study of the Herbig Be Star R Mon and the Associated HH 39 Herbig-Haro Object

    CERN Document Server

    Audard, M; Güdel, M; Lanz, T; Paerels, F; Arce, H

    2007-01-01

    We report on initial results of our Spitzer Cycle 2 program to observe the young massive star R Mon and its associated HH 39 Herbig-Haro object in the mid-infrared. Our program used all instruments on-board Spitzer to obtain deep images with IRAC of the HH 39 complex and of R Mon and its surroundings, a deep image of HH 39 at 24 and 70 $\\mu$m with MIPS, and mid-infrared spectra with the SH, LH, and LL modules of IRS. The aim of this program is to study the physical links in a young massive star between accretion disk, outflows and jets, and sh ocks in the associated HH object. Our preliminary analysis reveals that several knots of HH 39 are clearly detected in most IRAC bands. In IRAC4 (8 $\\mu$m), diffuse emission, probably from PAHs, appears as foreground emission covering the HH 39 emission. The HH 39 knots are detected at 24 microns, despite the fact that dust continuum emission covers the knots and shows the same structure as observed with IRAC4. The IRS spectra of HH 39 show weak evidence of [Ne II] 12.8...

  14. CDC WONDER: Sexually Transmitted Disease (STD) Morbidity

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Sexually Transmitted Disease (STD) Morbidity online databases on CDC WONDER contain case reports reported from the 50 United States and D.C., Puerto Rico, Virgin...

  15. CDC WONDER: Sexually Transmitted Disease (STD) morbidity

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Sexually Transmitted Disease (STD) Morbidity online databases on CDC WONDER contain case reports reported from the 50 United States and D.C., Puerto Rico, Virgin...

  16. syndromic management of sexually transmitted infections

    African Journals Online (AJOL)

    Kurt

    infectious disease service delivery. He has led ... referred to as classic sexually transmitted infections (STIs). ... chomoniasis) occur every year in developing countries.2 In South ... motion of STI prevention is often absent (most patients did not.

  17. Clinical update in sexually transmitted diseases-2014.

    Science.gov (United States)

    Fanfair, Robyn Neblett; Workowski, Kimberly A

    2014-02-01

    Sexually transmitted diseases (STDs) and their associated syndromes are extremely common in clinical practice. Early diagnosis, appropriate treatment, and partner management are important to ensure sexual, physical, and reproductive health in our patients.

  18. Sexually Transmitted Diseases: Teens at Risk.

    Science.gov (United States)

    Mascola, Laurene

    1987-01-01

    Parents of preteens need to be aware of the rapidly increasing incidence of sexually transmitted diseases among teenagers and to begin talking to their preteens to help prevent or modify risky sexual experimentation during middle adolescence. (MT)

  19. Transmitting boundary and radiation conditions at infinity

    Institute of Scientific and Technical Information of China (English)

    廖振鹏

    2001-01-01

    Relationship between the radiation conditions at infinity and the transmitting boundary for numerical simulation of the near-field wave motion has been studied in this paper. The conclusion is that the transmitting boundary is approximately equivalent to the radiation conditions at infinity for a large class of infinite media. And the errors of the approximation are of the same order of magnitude as those of the finite elements or finite differences in numerical simulation of wave motion. This result provides a sound theoretical basis for the transmitting boundary used in the numerical simulation of the near-field wave motion and gives a complete explanation for the major experiences accumulated in applications of the transmitting boundary to the numerical simulation.

  20. Vulnerability and Knowledge of Sexually Transmitted Infections ...

    African Journals Online (AJOL)

    hanumantp

    common causes of illness world-wide with far reaching health, ... Keywords: Enugu, Female traders, Knowledge, Prevention, Sexually transmitted infections, Vulnerability. Original ... constituted the work force, especially in developing countries.

  1. Knowledge of Sexually Transmitted Diseases among Secondary ...

    African Journals Online (AJOL)

    KeyWords: Sexually transmitted diseases, Adolescent, Knowledge, Information, ... AIDS is relatively low when compared to other locations in the country. ... be as a result of inadequate diagnostic and treatment facilities in the rural areas fear of.

  2. Tackling sexually transmitted infection burden in Ugandan ...

    African Journals Online (AJOL)

    Background: Despite being in a different country and social environment, Ugandans living in ... Keywords:sexually transmitted infection, Ugandan communities, .... their prevention to enable control programs take root. Methods. This study used ...

  3. Knowledge of sexually transmitted diseases among secondary ...

    African Journals Online (AJOL)

    Knowledge of sexually transmitted diseases among secondary school students in ... prevent the diseases among adolescent populations in developing countries. ... simple random sampling and stratified sampling methods was used to select ...

  4. Resolving the shocked gas in HH54 with Herschel: CO line mapping at high spatial and spectral resolution

    CERN Document Server

    Bjerkeli, P; Brinch, C; Olofsson, G; Santangelo, G; Cabrit, S; Benedettini, M; Black, J H; Herczeg, G; Justtanont, K; Kristensen, L E; Larsson, B; Nisini, B; Tafalla, M

    2014-01-01

    The HH54 shock is a Herbig-Haro object, located in the nearby Chamaeleon II cloud. Observed CO line profiles are due to a complex distribution in density, temperature, velocity, and geometry. Resolving the HH54 shock wave in the far-infrared cooling lines of CO constrain the kinematics, morphology, and physical conditions of the shocked region. We used the PACS and SPIRE instruments on board the Herschel space observatory to map the full FIR spectrum in a region covering the HH54 shock wave. Complementary Herschel-HIFI, APEX, and Spitzer data are used in the analysis as well. The observed features in the line profiles are reproduced using a 3D radiative transfer model of a bow-shock, constructed with the Line Modeling Engine code (LIME). The FIR emission is confined to the HH54 region and a coherent displacement of the location of the emission maximum of CO with increasing J is observed. The peak positions of the high-J CO lines are shifted upstream from the lower J CO lines and coincide with the position of ...

  5. Modelling the Emission And/or Absorption Features in the High Resolution Spectra of the Southern Binary System: HH Car

    Science.gov (United States)

    Koseoglu, Dogan; Bakış, Hicran

    2016-07-01

    High-resolution spectra (R=48000) of the southern close binary system, HH Car, has been analyzed with modern analysis techniques. Precise absolute parameters were derived from the simultaneous solution of the radial velocity, produced in this study and the light curves, published. According to the results of these analyses, the primary component is an O9 type main sequence star while the secondary component is a giant/subgiant star with a spectral type of B0. Hα emissions can be seen explicitly in the spectra of HH Car. These features were modelled using the absolute parameters of the components. Since components of HH Car are massive early-type stars, mass loss through stellar winds can be expected. This study revealed that the components of HH Car have stellar winds and the secondary component loses mass to the primary. Stellar winds and the gas stream between the components were modelled as a hot shell around the system. It is determined that the interaction between the winds and the gas stream leads to formation of a high temperature impact region.

  6. Vibration Characterization and Health Risk Assessment of the Vermont Army National Guard UH-72 Lakota and HH-60M MEDEVAC

    Science.gov (United States)

    2014-04-01

    Williams, HH60-M pilot, and 2LT Nathan Dubie, UH-72 pilot, for their unconditional support and guidance on the mockup activity, flight test...configurations, reviews, and test flights. Thanks to SGT Steve Lamonda, Aviation Life Support Systems Officer, for his help in the mockup and equipment

  7. The HH34 outflow as seen in [FeII]1.64um by LBT-LUCI

    CERN Document Server

    Antoniucci, S; Nisini, B; Giannini, T; Lorenzetti, D; Paris, D; Sani, E

    2014-01-01

    Dense atomic jets from young stars copiously emit in [FeII] IR lines, which can, therefore, be used to trace the immediate environments of embedded protostars. We want to investigate the morphology of the bright [FeII] 1.64um line in the jet of the source HH34 IRS and compare it with the most commonly used optical tracer [SII]. We analyse a 1.64um narrow-band filter image obtained with the Large Binocular Telescope (LBT) LUCI instrument, which covers the HH34 jet and counterjet. A Point Spread Function (PSF) deconvolution algorithm was applied to enhance spatial resolution and make the IR image directly comparable to a [SII] HST image of the same source. The [FeII] emission is detected from both the jet, the (weak) counter-jet, and from the HH34-S and HH34-N bow shocks. The deconvolved image allows us to resolve jet knots close to about 1\\arcsec from the central source. The morphology of the [FeII] emission is remarkably similar to that of the [SII] emission, and the relative positions of [FeII] and [SII] pea...

  8. Search and Rescue Aircrewman/HH3F Avionics, 2-11. Military Curriculum Materials for Vocational and Technical Education.

    Science.gov (United States)

    Ohio State Univ., Columbus. National Center for Research in Vocational Education.

    This self-paced, individualized course, adapted from military curriculum materials for use in vocational and technical education, teaches students the skills needed to become a qualified avionics worker and aircrew rescuer on the HH-3F helicopter. The course materials consist of four pamphlets: two student workbooks and two student syllabuses. The…

  9. The intracellular bacterium Wolbachia uses parasitoid wasps as phoretic vectors for efficient horizontal transmission.

    Directory of Open Access Journals (Sweden)

    Muhammad Z Ahmed

    2015-02-01

    Full Text Available Facultative bacterial endosymbionts are associated with many arthropods and are primarily transmitted vertically from mother to offspring. However, phylogenetic affiliations suggest that horizontal transmission must also occur. Such horizontal transfer can have important biological and agricultural consequences when endosymbionts increase host fitness. So far horizontal transmission is considered rare and has been difficult to document. Here, we use fluorescence in situ hybridization (FISH and multi locus sequence typing (MLST to reveal a potentially common pathway of horizontal transmission of endosymbionts via parasitoids of insects. We illustrate that the mouthparts and ovipositors of an aphelinid parasitoid become contaminated with Wolbachia when this wasp feeds on or probes Wolbachia-infected Bemisia tabaci AsiaII7, and non-lethal probing of uninfected B. tabaci AsiaII7 nymphs by parasitoids carrying Wolbachia resulted in newly and stably infected B. tabaci matrilines. After they were exposed to infected whitefly, the parasitoids were able to transmit Wolbachia efficiently for the following 48 h. Whitefly infected with Wolbachia by parasitoids had increased survival and reduced development times. Overall, our study provides evidence for the horizontal transmission of Wolbachia between insect hosts by parasitic wasps, and the enhanced survival and reproductive abilities of insect hosts may adversely affect biological control programs.

  10. Efficient heterologous expression and secretion in Aspergillus oryzae of a llama variable heavy-chain antibody fragment V(HH) against EGFR.

    Science.gov (United States)

    Okazaki, Fumiyoshi; Aoki, Jun-ichi; Tabuchi, Soichiro; Tanaka, Tsutomu; Ogino, Chiaki; Kondo, Akihiko

    2012-10-01

    We have constructed a filamentous fungus Aspergillus oryzae that secretes a llama variable heavy-chain antibody fragment (V(HH)) that binds specifically to epidermal growth factor receptor (EGFR) in a culture medium. A major improvement in yield was achieved by fusing the V(HH) with a Taka-amylase A signal sequence (sTAA) and a segment of 28 amino acids from the N-terminal region of Rhizopus oryzae lipase (N28). The yields of secreted, immunologically active anti-EGFR V(HH) reached 73.8 mg/1 in a Sakaguchi flask. The V(HH) fragments were released from the sTAA or N28 proteins by an indigenous A. oryzae protease during cultivation. The purified recombinant V(HH) fragment was specifically recognized and could bind to the EGFR with a high affinity.

  11. Sequential application of ligand and structure based modeling approaches to index chemicals for their hH4R antagonism.

    Directory of Open Access Journals (Sweden)

    Matteo Pappalardo

    Full Text Available The human histamine H4 receptor (hH4R, a member of the G-protein coupled receptors (GPCR family, is an increasingly attractive drug target. It plays a key role in many cell pathways and many hH4R ligands are studied for the treatment of several inflammatory, allergic and autoimmune disorders, as well as for analgesic activity. Due to the challenging difficulties in the experimental elucidation of hH4R structure, virtual screening campaigns are normally run on homology based models. However, a wealth of information about the chemical properties of GPCR ligands has also accumulated over the last few years and an appropriate combination of these ligand-based knowledge with structure-based molecular modeling studies emerges as a promising strategy for computer-assisted drug design. Here, two chemoinformatics techniques, the Intelligent Learning Engine (ILE and Iterative Stochastic Elimination (ISE approach, were used to index chemicals for their hH4R bioactivity. An application of the prediction model on external test set composed of more than 160 hH4R antagonists picked from the chEMBL database gave enrichment factor of 16.4. A virtual high throughput screening on ZINC database was carried out, picking ∼ 4000 chemicals highly indexed as H4R antagonists' candidates. Next, a series of 3D models of hH4R were generated by molecular modeling and molecular dynamics simulations performed in fully atomistic lipid membranes. The efficacy of the hH4R 3D models in discrimination between actives and non-actives were checked and the 3D model with the best performance was chosen for further docking studies performed on the focused library. The output of these docking studies was a consensus library of 11 highly active scored drug candidates. Our findings suggest that a sequential combination of ligand-based chemoinformatics approaches with structure-based ones has the potential to improve the success rate in discovering new biologically active GPCR drugs and

  12. CENTIMETER CONTINUUM OBSERVATIONS OF THE NORTHERN HEAD OF THE HH 80/81/80N JET: REVISING THE ACTUAL DIMENSIONS OF A PARSEC-SCALE JET

    Energy Technology Data Exchange (ETDEWEB)

    Masque, Josep M.; Estalella, Robert [Departament d' Astronomia i Meteorologia, Universitat de Barcelona, Marti i Franques 1, E-08028 Barcelona, Catalunya (Spain); Girart, Josep M. [Institut de Ciencies de l' Espai, (CSIC-IEEC), Campus UAB, Facultat de Ciencies, Torre C5-parell 2, E-08193 Bellaterra, Catalunya (Spain); Rodriguez, Luis F. [Centro de Radioastronomia y Astrofisica, Universidad Nacional Autonoma de Mexico, Apartado Postal 3-72, 58090 Morelia, Michoacan (Mexico); Beltran, Maria T. [INAF-Osservatorio Astrofisico di Arcetri, Largo E. Fermi 5, I-50125 Firenze (Italy)

    2012-10-10

    We present 6 and 20 cm Jansky Very Large Array/Very Large Array observations of the northern head of the HH 80/81/80N jet, one of the largest collimated jet systems known so far, aimed to look for knots farther than HH 80N, the northern head of the jet. Aligned with the jet and 10' northeast of HH 80N, we found a radio source not reported before, with a negative spectral index similar to that of HH 80, HH 81, and HH 80N. The fit of a precessing jet model to the knots of the HH 80/81/80N jet, including the new source, shows that the position of this source is close to the jet path resulting from the modeling. If the new source belongs to the HH 80/81/80N jet, its derived size and dynamical age are 18.4 pc and >9 Multiplication-Sign 10{sup 3} yr, respectively. If the jet is symmetric, its southern lobe would expand beyond the cloud edge resulting in an asymmetric appearance of the jet. Based on the updated dynamical age, we speculate on the possibility that the HH 80/81/80N jet triggered the star formation observed in a dense core found ahead of HH 80N, which shows signposts of interaction with the jet. These results indicate that parsec-scale radio jets can play a role in the stability of dense clumps and the regulation of star formation in the molecular cloud.

  13. The Sinorhizobium fredii HH103 lipopolysaccharide is not only relevant at early soybean nodulation stages but also for symbiosome stability in mature nodules.

    Directory of Open Access Journals (Sweden)

    Isabel Margaret

    Full Text Available In this work we have characterised the Sinorhizobium fredii HH103 greA lpsB lpsCDE genetic region and analysed for the first time the symbiotic performance of Sinorhizobium fredii lps mutants on soybean. The organization of the S. fredii HH103 greA, lpsB, and lpsCDE genes was equal to that of Sinorhizobium meliloti 1021. S. fredii HH103 greA, lpsB, and lpsE mutant derivatives produced altered LPS profiles that were characteristic of the gene mutated. In addition, S. fredii HH103 greA mutants showed a reduction in bacterial mobility and an increase of auto-agglutination in liquid cultures. RT-PCR and qPCR experiments demonstrated that the HH103 greA gene has a positive effect on the transcription of lpsB. Soybean plants inoculated with HH103 greA, lpsB or lpsE mutants formed numerous ineffective pseudonodules and showed severe symptoms of nitrogen starvation. However, HH103 greA and lps mutants were also able to induce the formation of a reduced number of soybean nodules of normal external morphology, allowing the possibility of studying the importance of bacterial LPS in later stages of the S. fredii HH103-soybean symbiosis. The infected cells of these nodules showed signs of early termination of symbiosis and lytical clearance of bacteroids. These cells also had very thick walls and accumulation of phenolic-like compounds, pointing to induced defense reactions. Our results show the importance of bacterial LPS in later stages of the S. fredii HH103-soybean symbiosis and their role in preventing host cell defense reactions. S. fredii HH103 lpsB mutants also showed reduced nodulation with Vigna unguiculata, although the symbiotic impairment was less pronounced than in soybean.

  14. NopC Is a Rhizobium-Specific Type 3 Secretion System Effector Secreted by Sinorhizobium (Ensifer) fredii HH103

    Science.gov (United States)

    Medina, Carlos; Ollero, Francisco Javier; López-Baena, Francisco Javier

    2015-01-01

    Sinorhizobium (Ensifer) fredii HH103 is a broad host-range nitrogen-fixing bacterium able to nodulate many legumes, including soybean. In several rhizobia, root nodulation is influenced by proteins secreted through the type 3 secretion system (T3SS). This specialized secretion apparatus is a common virulence mechanism of many plant and animal pathogenic bacteria that delivers proteins, called effectors, directly into the eukaryotic host cells where they interfere with signal transduction pathways and promote infection by suppressing host defenses. In rhizobia, secreted proteins, called nodulation outer proteins (Nops), are involved in host-range determination and symbiotic efficiency. S. fredii HH103 secretes at least eight Nops through the T3SS. Interestingly, there are Rhizobium-specific Nops, such as NopC, which do not have homologues in pathogenic bacteria. In this work we studied the S. fredii HH103 nopC gene and confirmed that its expression was regulated in a flavonoid-, NodD1- and TtsI-dependent manner. Besides, in vivo bioluminescent studies indicated that the S. fredii HH103 T3SS was expressed in young soybean nodules and adenylate cyclase assays confirmed that NopC was delivered directly into soybean root cells by means of the T3SS machinery. Finally, nodulation assays showed that NopC exerted a positive effect on symbiosis with Glycine max cv. Williams 82 and Vigna unguiculata. All these results indicate that NopC can be considered a Rhizobium-specific effector secreted by S. fredii HH103. PMID:26569401

  15. Panspermia and horizontal gene transfer

    Science.gov (United States)

    Klyce, Brig

    2009-08-01

    Evidence that extremophiles are hardy and ubiquitous is helping to make panspermia a respectable theory. But even if life on Earth originally came from space, biologists assume that the subsequent evolution of life is still governed by the darwinian paradigm. In this review we show how panspermia could amend darwinism and point to a cosmic source for, not only extremophiles but, all of life. This version of panspermia can be called "strong panspermia." To support this theory we will discuss recent evidence pertaining to horizontal gene transfer, viruses, genes apparently older than the Earthly evolution of the features they encode, and primate-specific genes without identifiable precursors.

  16. Perceptions of sexually transmitted diseases among teenagers

    Directory of Open Access Journals (Sweden)

    DM Diale

    2000-09-01

    Full Text Available An ex p lo ra to ry d e sc rip tiv e study was u n d e rtak en , focussing on sexually transmitted diseases (STD among teenagers. The aim of the study was to explore and describe the possible reasons for the high rate of sexually transmitted diseases in teenagers. The perceptions of teenagers and community nurses regarding sexually transmitted disease among teenagers involved in the teenage clinic in a specific predominantly black area were assessed. Twenty teenagers and five community nurses were participants in the study. Two focus group interviews were conducted with teenagers and community nurses. It can be concluded that the attitudes of community nurses may have an influence on the high rate of sexually transmitted diseases among teenagers. The knowledge o f the teenagers about sexually transmitted diseases is often based on myths and misconceptions which could be intensified by the community nurse. The recommendations made are that the education standards of all community nurses should be reviewed and adapted to meet the needs of teenagers attending the teenage health services. The policy on in-service training must be reviewed and monitored. Community nurses’ intensive training on teenage health service delivery and sexually transmitted diseases services should be in accordance with the principles of Primary Health Care. Community nurses need to attend intensive courses on interpersonal skills specifically related to teenagers. Selection procedures for recruiting community nurses to attend to teenagers specifically should be researched. Teenagers should be involved in planning programs and the teenage clinic should be evaluated frequently to improve the standards. The availability of adequate teenage health services can result in a decrease in sexually transmitted diseases among teenagers.

  17. The small-scale HH34 IRS jet as seen by X-shooter

    Science.gov (United States)

    Nisini, B.; Giannini, T.; Antoniucci, S.; Alcalá, J. M.; Bacciotti, F.; Podio, L.

    2016-11-01

    Context. Atomic jets are a common phenomenon among young stars, being intimately related to disk accretion. Most studies have been performed on jets from pre-main sequence stars. However, to date very little detailed information has been gathered on jets from young embedded low mass sources (the so-called class I stars), especially in the inner jet region. Aims: We exploit a diagnostic analysis based on multiwave spectroscopic observations to infer kinematics and physical conditions of the inner region of the prototypical class I jet from HH34 IRS. Methods: We use a deep X-shooter spectrum covering the wavelength range 350-2300 nm at resolution between 8000 and 18 000 (i.e., ΔV 17-27 km s-1), which allows us to detect lines in a wide range of excitation conditions (from Eup 8000 to 31 000 cm-1 ) and to study their kinematics. Statistical equilibrium and ionization models are adopted to derive the jet main physical parameters. Results: We separately derive the physical conditions for the extended high velocity jet (HVC, Vr -100 km s-1 ) and for the low velocity and compact gas (LVC, Vr -20-50 km s-1) located on-source. Close to the jet base ( 5 × 105 cm-3). The LVC gas has the same density and AV as the HVC, but it is at least a factor of two colder. Iron abundance in the HVC is consistent with the solar value, while it is a factor of 3 subsolar in the LVC, suggesting an origin of the LVC gas from a dusty disk. From the derived total density we infer that the jet mass flux rate is >5 × 10-7M⊙ yr-1. We find that the relationships between accretion luminosity and permitted line luminosity derived for T Tauri stars cannot be directly extended to class I sources embedded in reflection nebulae since the permitted lines are seen through scattered light. An accretion rate of 7 × 10-6M⊙ yr-1 is instead derived from an empirical relationship connecting Ṁacc with L([O i])(HVC). Conclusions: The class I HH34 IRS jet at small scale shares many kinematical and physical

  18. Horizontal gene transfer in chromalveolates

    Directory of Open Access Journals (Sweden)

    Bhattacharya Debashish

    2007-09-01

    Full Text Available Abstract Background Horizontal gene transfer (HGT, the non-genealogical transfer of genetic material between different organisms, is considered a potentially important mechanism of genome evolution in eukaryotes. Using phylogenomic analyses of expressed sequence tag (EST data generated from a clonal cell line of a free living dinoflagellate alga Karenia brevis, we investigated the impact of HGT on genome evolution in unicellular chromalveolate protists. Results We identified 16 proteins that have originated in chromalveolates through ancient HGTs before the divergence of the genera Karenia and Karlodinium and one protein that was derived through a more recent HGT. Detailed analysis of the phylogeny and distribution of identified proteins demonstrates that eight have resulted from independent HGTs in several eukaryotic lineages. Conclusion Recurring intra- and interdomain gene exchange provides an important source of genetic novelty not only in parasitic taxa as previously demonstrated but as we show here, also in free-living protists. Investigating the tempo and mode of evolution of horizontally transferred genes in protists will therefore advance our understanding of mechanisms of adaptation in eukaryotes.

  19. Horizontal versus vertical plate motions

    Directory of Open Access Journals (Sweden)

    M. Cuffaro

    2006-07-01

    Full Text Available We review both present and past motions at major plate boundaries, which have the horizontal component in average 10 to 100 times faster (10–100 mm/yr than the vertical component (0.01–1 mm/yr in all geodynamic settings. The steady faster horizontal velocity of the lithosphere with respect to the upward or downward velocities at plate boundaries supports dominating tangential forces acting on plates. This suggests a passive role of plate boundaries with respect to far field forces determining the velocity of plates. The forces acting on the lithosphere can be subdivided in coupled and uncoupled, as a function of the shear at the lithosphere base. Higher the asthenosphere viscosity, more significant should be the coupled forces, i.e., the mantle drag and the trench suction. Lower the asthenosphere viscosity, more the effects of uncoupled forces might result determinant, i.e., the ridge push, the slab pull and the tidal drag. Although a combination of all forces acting on the lithosphere is likely, the decoupling between lithosphere and mantle suggests that a torque acts on the lithosphere independently of the mantle drag. Slab pull and ridge push are candidates for generating this torque, but, unlike these boundary forces, the advantage of the tidal drag is to be a volume force, acting simultaneously on the whole plates, and being the decoupling at the lithosphere base controlled by lateral variations in viscosity of the low-velocity layer.

  20. New cosmic rays experiments in the underground laboratory of IFIN-HH from Slanic Prahova, Romania

    Energy Technology Data Exchange (ETDEWEB)

    Mitrica, Bogdan; Stanca, Denis; Brancus, Iliana; Margineanu, Romul; Blebea-Apostu, Ana-Maria; Gomoiu, Claudia; Saftoiu, Alexandra; Toma, Gabriel; Gherghel-Lascu, Alexandru; Niculescu-Oglinzanu, Mihai [Horia Hulubei National Institute of Physics and Nuclear Engineering - IFIN HH, P.O.B. MG-6, Bucharest (Romania); Rebel, Heinigerd; Haungs, Andreas [Institute of Experimental Nuclear Physics, Karlsruhe Institute of Technology-Campus North, 76021 Karlsruhe (Germany); Sima, Octavian [Department of Physics, University of Bucharest, 077125 Magurele (Romania)

    2015-02-24

    Since 2006 a modern laboratory has been developed by IFIN-HH in the underground of Slanic Prahova salt ore. This work presents a short review of previous scientific activities performed in the underground laboratory, in parallel with some plans for the future. A mobile detector for cosmic muon flux measurements has been set up at IFIN-HH, Romania. The device is used to measure the muon flux on different locations at the surface and underground and it consists of two detection layers, each one including four large scintillator plates. A new rotatable detector for measurements of the directional variation of the muon flux has been designed and it is presently under preliminary tests. Built from four layers of sensitive material and using for collecting the signals and directing them to the micro PMTs a new technique, through optical fibers instead wave length shifters, it allows an easy discrimination of the moun flux on the arrival directions of muons. Combining the possibility to rotate and the directionality properties, the underground muon detector is acting like a muon tomography device, being able to scan, using cosmic muons, the rock material above the detector. In parallel new detection system based on SiPM will be also installed in the following weeks. It should be composed by four layers, each layer consisting in 4 scintillator plates what we consider in the following as a module of detection. For this purpose, first two scintillator layers, with the optical fibers positioned on perpendicular directions are put in coincidence with other two layers, 1 m distance from the first two, with similar optical fiber arrangement, thus allowing reconstructing muon trajectory. It is intended also to design and construct an experimental device for the investigation of such radio antennas and the behavior of the signal in rock salt at the Slanic salt mine in Romania. Another method to detect high energy neutrinos is based on the detection of secondary particles resulting

  1. Adaptive transmit selection with interference suppression

    KAUST Repository

    Radaydeh, Redha Mahmoud Mesleh

    2010-01-01

    This paper studies the performance of adaptive transmit channel selection in multipath fading channels. The adaptive selection algorithms are configured for single-antenna bandwidth-efficient or power-efficient transmission with as low transmit channel estimations as possible. Due to the fact that the number of active co-channel interfering signals and their corresponding powers experience random behavior, the adaptation to channels conditions, assuming uniform buffer and traffic loading, is proposed to be jointly based on the transmit channels instantaneous signal-to-noise ratios (SNRs) and signal-to- interference-plus- noise ratios (SINRs). Two interference cancelation algorithms, which are the dominant cancelation and the less complex arbitrary cancelation, are considered, for which the receive antenna array is assumed to have small angular spread. Analytical formulation for some performance measures in addition to several processing complexity and numerical comparisons between various adaptation schemes are presented. ©2010 IEEE.

  2. Syndromes Associated with Sexually Transmitted Infections

    Directory of Open Access Journals (Sweden)

    Max Chernesky

    2005-01-01

    Full Text Available Excellent technologies have been developed to identify the specific microbial agents of chlamydia, gonorrhea, syphilis, herpes, chancroid, trichomoniasis, human papillomavirus and HIV infection. However, it is also crucial to recognize syndromes that may be caused by one or more sexually transmitted pathogens. When laboratory services are lacking or are inadequate to provide timely results to enable appropriate treatment, some patients must be managed and treated syndromically. Most Canadian laboratories should be able to provide diagnostic services to determine the etiology of syndromes such as cervicitis, urethritis, pelvic inflammatory disease, prostatitis, genital ulcers, sexually transmitted infection (STI-related enteric infections, epididymitis, hepatitis, ophthalmia neonatorum, vulvovaginitis and vaginosis.

  3. A highly-collimated SiO jet in the HH212 protostellar outflow

    CERN Document Server

    Codella, C; Gueth, F; Cesaroni, R; Bacciotti, F; Le Floc'h, B; McCaughrean, M J

    2006-01-01

    We mapped the HH212 Class 0 outflow in SiO(2--1, 5--4) and continuum using the PdBI in its extended configurations. The unprecedented angular resolution (down to 0.34") allows accurate comparison with a new, deep H2 image obtained at the VLT. The SiO emission is confined to a highly-collimated bipolar jet (width 0.35") along the outflow axis. The jet can be traced down to within 500 AU of the protostar, in a region that is heavily obscured in H2 images. Where both species are detected, SiO shows the same overall kinematics and structure as H2, indicating that both molecules are tracing the same material. We find that the high-velocity SiO gas near the protostar is not tracing a wide-angle wind but is already confined to a flow inside a narrow cone of half-opening angle < 6 deg.

  4. Solving the excitation and chemical abundances in shocks: the case of HH1

    CERN Document Server

    Giannini, T; Nisini, B; Bacciotti, F; Podio, L

    2015-01-01

    We present deep spectroscopic (3600 - 24700 A) X-shooter observations of the bright Herbig-Haro object HH1, one of the best laboratories to study the chemical and physical modifications caused by protostellar shocks on the natal cloud. We observe atomic fine structure lines, HI, and He, recombination lines and H_2, ro-vibrational lines (more than 500 detections in total). Line emission was analyzed by means of Non Local Thermal Equilibiurm codes to derive the electron temperature and density, and, for the first time, we are able to accurately probe different physical regimes behind a dissociative shock. We find a temperature stratification in the range 4000 - 80000 K, and a significant correlation between temperature and ionization energy. Two density regimes are identified for the ionized gas, a more tenuous, spatially broad component (density about 10^3 cm^-3), and a more compact component (density > 10^5 cm^-3) likely associated with the hottest gas. A further neutral component is also evidenced, having te...

  5. A combined optical/infrared spectral diagnostic analysis of the HH1 jet

    CERN Document Server

    Nisini, B; Giannini, T; Massi, F; Eislöffel, J; Podio, L; Ray, T P; Nisini, Brunella; Bacciotti, Francesca; Giannini, Teresa; Massi, Fabrizio; Eisl\\"offel, Jochen; Podio, Linda; Ray, Thomas P.

    2005-01-01

    Complete flux-calibrated spectra covering the spectral range from 6000 A to 2.5 um have been obtained along the HH1 jet and analysed in order to explore the potential of a combined optical/near-IR diagnostic applied to jets from young stellar objects. Important physical parameters have been derived along the jet using various diagnostic line ratios. This multi-line analysis shows, in each spatially unresolved knot, the presence of zones at different excitation conditions, as expected from the cooling layers behind a shock front. In particular, a density stratification in the jet is evident from ratios of various lines of different critical density. In particular, [FeII] lines originate in a cooling layer located at larger distances from the shock front than that generating the optical lines, where the compression is higher and the temperature is declining. The derived parameters were used to measure the mass flux along the jet, adopting different procedures, the advantages and limitations of which are discuss...

  6. IR diagnostics of embedded jets: kinematics and physical characteristics of the HH46-47 jet

    CERN Document Server

    Lopez, Rebeca Garcia; Eisloeffel, Jochen; Giannini, Teresa; Bacciotti, Francesca; Podio, Linda

    2009-01-01

    We present an analysis of the kinematics and physical properties of the Class I driven jet HH46-47 based on IR medium and low resolution spectroscopy obtained with ISAAC on VLT. Our aim is to study the gas physics as a function of the velocity and distance from the source and compare the results with similar studies performed on other Class I and CTTS jets, as well as with existing models for the jet formation and excitation. The ratios and luminosities of several important diagnostic lines have been used to derive physical parameters. [FeII] and H2 Position Velocity Diagrams (PVDs) have been in addition constructed to study the kinematics. Within 1000-2000 AU from the source the atomic gas presents a wide range of radial velocities. Only the gas component at the highest velocity (HVC) survives at large distances. The H2, shows, close to the source, only a single velocity component at almost zero velocity, while it reaches higer velocities further downstream. Electron densities (ne) and mass ejection fluxes (...

  7. Spitzer observations of the HH 1/2 system. The discovery of the counterjet

    CERN Document Server

    Noriega-Crespo,; Raga,; C, A

    2012-01-01

    We present unpublished Spitzer IRAC observations of the HH 1/2 young stellar outflow processed with a high angular resolution deconvolution algorithm that produces sub-arcsecond (approx. 0.6" - 0.8") images. In the resulting mid-infrared images the optically invisible counterjet is detected for the first time. The counterjet is approximately half as bright as the jet at 4.5 micron (the IRAC band that best traces young stellar outflows) and has a length of approx. 10". The NW optical jet itself can be followed back in the mid-IR to the position of the exciting VLA 1 source. An analysis of the IRAC colors indicates that the jet/counterjet emission is dominated by collisionally excited H2 pure rotational lines arising from a medium with a neutral Hydrogen gas density of 1000-2000 per cubic cm and a temperature of 1500 K. The observed jet/counterjet brightness asymmetry is consistent with an intrinsically symmetric outflow with extinction from a dense, circumstellar structure of 6" size (along the outflow axis), ...

  8. SPITZER OBSERVATIONS OF THE HH 1/2 SYSTEM: THE DISCOVERY OF THE COUNTERJET

    Energy Technology Data Exchange (ETDEWEB)

    Noriega-Crespo, A. [Infrared Processing and Analysis Center, California Institute of Technology, Pasadena, CA 91125 (United States); Raga, A. C. [Instituto de Ciencias Nucleares, Universidad Nacional Autonoma de Mexico, Ap. 70-543, 04510 D.F. (Mexico)

    2012-05-10

    We present unpublished Spitzer IRAC observations of the HH 1/2 young stellar outflow processed with a high angular resolution deconvolution algorithm that produces subarcsecond ({approx}0.''6-0.''8) images. In the resulting mid-infrared images, the optically invisible counterjet is detected for the first time. The counterjet is approximately half as bright as the jet at 4.5 {mu}m (the IRAC band that best traces young stellar outflows) and has a length of {approx}10''. The NW optical jet itself can be followed back in the mid-IR to the position of the exciting VLA 1 source. An analysis of the IRAC colors indicates that the jet/counterjet emission is dominated by collisionally excited H{sub 2} pure rotational lines arising from a medium with a neutral hydrogen gas density of {approx}1000-2000 cm{sup -3} and a temperature of {approx} 1500 K. The observed jet/counterjet brightness asymmetry is consistent with an intrinsically symmetric outflow with extinction from a dense, circumstellar structure of {approx}6'' size (along the outflow axis), and with a mean visual extinction, A{sub V} {approx} 11 mag.

  9. Hot methanol from the inner region of the HH 212 protostellar system

    Science.gov (United States)

    Leurini, S.; Codella, C.; Cabrit, S.; Gueth, F.; Giannetti, A.; Bacciotti, F.; Bachiller, R.; Ceccarelli, C.; Gusdorf, A.; Lefloch, B.; Podio, L.; Tafalla, M.

    2016-10-01

    The mechanisms leading to the formation of disks around young stellar objects (YSOs) and to the launching of the associated jets are crucial to the understanding of the earliest stages of star and planet formation. HH 212 is a privileged laboratory to study a pristine jet-disk system. Therefore we investigate the innermost region (uv plane of various velocity channels of the strongest high-excitation lines. The blue- and red-shifted velocity centroids are shifted roughly symmetrically on either side of the jet axis, indicating that the line-of-sight velocity beyond 0.7 km s-1 from systemic is dominated by rotational motions. The velocity increases moving away from the protostar further indicating that the emission of methanol is not associated with a Keplerian disk or rotating-infalling cavity, and it is more likely associated with outflowing gas. We speculate that CH3OH traces a disk wind gas accelerated at the base. The launching region would be at a radius of a few astronomical units from the YSO.

  10. Circular polarimetry reveals helical magnetic fields in the young stellar object HH 135-136

    CERN Document Server

    Chrysostomou, Antonio; Hough, James H

    2007-01-01

    Magnetic fields are believed to have a vital role in regulating and shaping the flow of material onto and away from protostars during their initial mass accretion phase. It is becoming increasingly accepted that bipolar outflows are generated and collimated as material is driven along magnetic field lines and centrifugally accelerated off a rotating accretion disk. However, the precise role of the magnetic field is poorly understood and evidence for its shape and structure has not been forthcoming. Here we report imaging circular polarimetry in the near-infrared and Monte Carlo modelling showing that the magnetic field along the bipolar outflow of the HH 135-136 young stellar object is helical. The field retains this shape for large distances along the outflow, so the field structure can also provide the necessary magnetic pressure for collimation of the outflow. This result lends further weight to the hypothesis - central to any theory of star formation - that the outflow is an important instrument for the r...

  11. Late-Type Near-Contact Eclipsing Binary [HH97] FS Aur-79

    CERN Document Server

    Austin, S J; Tycner, C; Campbell, T; Honeycutt, R K

    2007-01-01

    The secondary photometric standard star #79 for the FS Aur field (Henden & Honeycutt 1997) designated as [HH97] FS Aur-79 (GSC 1874 399) is a short period (0.2508 days) eclipsing binary whose light curve is a combination of the $\\beta$ Lyr and BY Dra type variables. High signal-to-noise multi-color photometry were obtained using the USNO 1-m telescope. These light curves show asymmetry at quadrature phases (O'Connell effect), which can be modeled with the presence of star spots. A low resolution spectrum obtained with the 3.5-m WIYN telescope at orbital phase 0.76 is consistent with a spectral type of dK7e and dM3e. A radial velocity curve for the primary star was constructed using twenty-four high resolution spectra from the 9.2 m HET. Spectra show H-alpha and H-beta in emission confirming chromospheric activity and possibly the presence of circumstellar material. Binary star models that simultaneously fit the U, B, V, R and RV curves are those with a primary star of mass 0.59+-0.02 Msun, temperature 410...

  12. The small-scale HH34 IRS jet as seen by X-shooter

    CERN Document Server

    Nisini, B; Antoniucci, S; Alcala', J M; Bacciotti, F; Podio, L

    2016-01-01

    Very little information has been so far gathered on atomic jets from young embedded low mass sources (class I stars), especially in the inner jet region. We exploit multiwave spectroscopic observations to infer physical conditions of the inner region of HH34 IRS, a prototypical class I jet. We use a deep X-shooter spectrum ( lambda = 350-2300 nm, R between 8000 and 18000) detecting lines with upper energies from 8000 to 31000 cm-1 . Statistical equilibrium and ionization models are adopted to derive the jet main physical parameters. We derive the physical conditions for the extended high velocity jet (HVC, V about -100 km/s) and for the low velocity and compact gas (LVC, V about -20-50 \\kms). At the jet base ( 5x10^5 cm-3). The LVC gas has the same density and A_V as the HVC, but it is a factor of two colder. Iron abundance in the HVC is close to solar, while it is 3 times subsolar in the LVC, suggesting an origin of the LVC gas from a dusty disk. We infer a jet mass flux rate > 5x10^{-7} Mo/yr. We find that ...

  13. Physical Structure and Dust Reprocessing in a sample of HH Jets

    CERN Document Server

    Podio, L; Bacciotti, F; Eislöffel, J; Ray, T P

    2009-01-01

    We investigate the physical structure and dust reprocessing in the shocks along the beam of a number of classical Herbig-Haro jets in the Orion and Lupus molecular cloud. Spectral diagnostic techniques are applied to obtain the jet physical conditions from the ratios between selected forbidden lines. The presence of dust grains is investigated by estimating the gas-phase abundance of calcium with respect to its Solar value. We find the electron density, ne, varies between 0.05-4 10^3 cm^-3, the ionisation fraction, xe, is 0.01-0.7, the temperature, te, ranges between 0.6-3 10^4 K, and the hydrogen density between 0.01-6 10^4 cm^-3. Interestingly, in the HH 111 jet, ne, xe, and te, peak in the High Velocity Interval (HVI) of the strongest working surfaces, confirming the prediction from shocks models. Calcium turns out to be depleted with respect to its Solar value, but its gas-phase abundance is higher than that estimated in the interstellar medium in Orion. The depletion is high (up to 80%) along the low-exc...

  14. The Structure of the Inner HH 34 Jet from Optical Integral Field Spectroscopy

    CERN Document Server

    Beck, T L; Raga, A C; Reipurth, B; Beck, Tracy L.; Reipurth, Bo

    2006-01-01

    We present high spatial resolution optical integral field spectroscopy of a collimated Herbig-Haro jet viewed nearly edge-on. Maps of the line emission, velocity centroid, and velocity dispersion were generated for the H$\\alpha$ and [S II] emission features from the inner collimated jet and exciting source region of the HH 34 outflow. The kinematic structure of the jet shows several maxima and minima in both velocity centroid value and velocity dispersion along the jet axis. Perpendicular to the flow direction the velocity decreases outward from the axis to the limb of the jet, but the velocity dispersion increases. Maps of the electron density structure were derived from the line ratio of [S II] 6731/6716 emission. We have found that the jet exhibits a pronounced ``striped'' pattern in electron density; the high $n_e$ regions are at the leading side of each of the emission knots in the collimated jet, and low $n_e$ regions in the down-flow direction. On average, the measured electron density decreases outwar...

  15. Herschel observations of the Herbig-Haro objects HH52-54

    CERN Document Server

    Bjerkeli, P; Nisini, B; Tafalla, M; Benedettini, M; Bergman, P; Dionatos, O; Giannini, T; Herczeg, G; Justtanont, K; Larsson, B; McCoey, C; Olberg, M; Olofsson, A O H

    2011-01-01

    We are aiming at the observational estimation of the relative contribution to the cooling by CO and H2O, as this provides decisive information for the understanding of the oxygen chemistry behind interstellar shock waves. Methods. The high sensitivity of HIFI, in combination with its high spectral resolution capability, allows us to trace the H2O outflow wings at unprecedented signal-to-noise. From the observation of spectrally resolved H2O and CO lines in the HH52-54 system, both from space and from ground, we arrive at the spatial and velocity distribution of the molecular outflow gas. Solving the statistical equilibrium and non-LTE radiative transfer equations provides us with estimates of the physical parameters of this gas, including the cooling rate ratios of the species. The radiative transfer is based on an ALI code, where we use the fact that variable shock strengths, distributed along the front, are naturally implied by a curved surface. Based on observations of CO and H2O spectral lines, we conclud...

  16. Spitzer spectral line mapping of the HH211 outflow

    DEFF Research Database (Denmark)

    Dionatos, Odyssefs; Nisini, Brunella; Cabrit, Sylvie

    2010-01-01

    of emission line diagnostics and an existing grid of molecular shock models. The physical properties of the warm gas are compared against other molecular jet tracers and to the results of a similar study towards the L1448-C outflow. Results: We have detected and mapped the v=0-0 S(0) - S(7) H2 lines and fine...... fitted by C-type shocks with a low beam filling factor ~ 0.01-0.04 and a mass-flux similar to the cool H2. The fine-structure line emission arises from dense gas with ionization fraction ~0.5 - 5 x 10e-3, suggestive of dissociative shocks. Line ratios to sulfur indicate that iron and silicon are depleted...... compared to solar abundances by a factor ~10-50. Conclusions: Spitzer spectral mapping observations reveal for the first time a cool H$_2$ component towards the CO jet of HH211 consistent with the CO material being fully molecular and warm at ~ 300 K. The maps also reveal for the first time the existence...

  17. Kinematics of SiO J=8-7 Emission towards the HH 212 Jet

    CERN Document Server

    Takami, M; Momose, M; Hayashi, M; Davis, C; Pyo, T S; Nishikawa, T; Kohno, K; Takami, Michihiro; Takamuwa, Shigehisa; Momose, Munetake; Hayashi, Masa; Davis, Christopher; Pyo, Tae-Soo; Nishikawa, Takayuki; Kohno, Kotaro

    2006-01-01

    We present SiO J=8-7 (347.3 GHz) observations towards HH 212 using the ASTE telescope. Our observations with a 22''-diameter beam show that the SiO emission is highly concentrated within 1' of the driving source. We carefully compare the SiO observations with archival H_2 1-0 S(1) images and published H_2 echelle spectra. We find that, although the SiO velocities closely match the radial velocities seen in H_2, the distribution of H_2 and SiO emission differ markedly. We attribute the latter to the different excitation conditions required for H_2 and SiO emission, particularly the higher critical density (n_H2 ~10^8 cm^-3) of the SiO J=8-7 emission. The kinematic similarities imply that the H_2 and SiO are associated with the same internal working surfaces. We conclude that the SiO J=8-7 emission has a potential to probe the jet/wind launching region through interferometric observations in the future, particularly for the youngest, most deeply embedded protostars where IR observations are not possible.

  18. A new ion beam facility based on a 3 MV Tandetron™ at IFIN-HH, Romania

    Energy Technology Data Exchange (ETDEWEB)

    Burducea, I.; Straticiuc, M. [Horia Hulubei National Institute of Physics and Nuclear Engineering, IFIN-HH, Măgurele 077125 (Romania); Ghiță, D.G., E-mail: dan.ghita@nipne.ro [Horia Hulubei National Institute of Physics and Nuclear Engineering, IFIN-HH, Măgurele 077125 (Romania); Moșu, D.V.; Călinescu, C.I. [Horia Hulubei National Institute of Physics and Nuclear Engineering, IFIN-HH, Măgurele 077125 (Romania); Podaru, N.C.; Mous, D.J.W. [High Voltage Engineering Europa B.V., P.O. Box 99, 3800AB Amersfoort (Netherlands); Ursu, I.; Zamfir, N.V. [Horia Hulubei National Institute of Physics and Nuclear Engineering, IFIN-HH, Măgurele 077125 (Romania)

    2015-09-15

    A 3 MV Tandetron™ accelerator system has been installed and commissioned at the “Horia Hulubei” National Institute for Physics and Nuclear Engineering – IFIN-HH, Măgurele, Romania. The main purpose of this machine is to strengthen applied nuclear physics research ongoing in our institute for more than four decades. The accelerator system was developed by High Voltage Engineering Europa B.V. (HVE) and comprises three high energy beam lines. The first beam line is dedicated to ion beam analysis (IBA) techniques: Rutherford Backscattering Spectrometry – RBS, Nuclear Reaction Analysis – NRA, Particle Induced X-ray and γ-ray Emission – PIXE and PIGE and micro-beam experiments – μ-PIXE. The second beam line is dedicated to high energy ion implantation experiments and the third beam line was designed mainly for nuclear cross-sections measurements used in nuclear astrophysics. A unique feature, the first time in operation at an accelerator facility is the Na charge exchange canal (CEC), which is used to obtain high intensity beams of He{sup −} of at least 3 μA. The results of the acceptance tests demonstrate the huge potential of this new facility in various fields, from IBA to radiation hardness studies and from medical or environmental applications to astrophysics. The main features of the accelerator are presented in this paper.

  19. A new ion beam facility based on a 3 MV Tandetron™ at IFIN-HH, Romania

    Science.gov (United States)

    Burducea, I.; Straticiuc, M.; Ghiță, D. G.; Moșu, D. V.; Călinescu, C. I.; Podaru, N. C.; Mous, D. J. W.; Ursu, I.; Zamfir, N. V.

    2015-09-01

    A 3 MV Tandetron™ accelerator system has been installed and commissioned at the "Horia Hulubei" National Institute for Physics and Nuclear Engineering - IFIN-HH, Măgurele, Romania. The main purpose of this machine is to strengthen applied nuclear physics research ongoing in our institute for more than four decades. The accelerator system was developed by High Voltage Engineering Europa B.V. (HVE) and comprises three high energy beam lines. The first beam line is dedicated to ion beam analysis (IBA) techniques: Rutherford Backscattering Spectrometry - RBS, Nuclear Reaction Analysis - NRA, Particle Induced X-ray and γ-ray Emission - PIXE and PIGE and micro-beam experiments - μ-PIXE. The second beam line is dedicated to high energy ion implantation experiments and the third beam line was designed mainly for nuclear cross-sections measurements used in nuclear astrophysics. A unique feature, the first time in operation at an accelerator facility is the Na charge exchange canal (CEC), which is used to obtain high intensity beams of He- of at least 3 μA. The results of the acceptance tests demonstrate the huge potential of this new facility in various fields, from IBA to radiation hardness studies and from medical or environmental applications to astrophysics. The main features of the accelerator are presented in this paper.

  20. MULTI-COMPONENT ANALYSIS OF POSITION-VELOCITY CUBES OF THE HH 34 JET

    Energy Technology Data Exchange (ETDEWEB)

    Rodriguez-Gonzalez, A.; Esquivel, A.; Raga, A. C. [Instituto de Ciencias Nucleares, Universidad Nacional Autonoma de Mexico, Ap. 70-543, 04510 DF (Mexico); Canto, J.; Curiel, S. [Instituto de Astronomia, Universidad Nacional Autonoma de Mexico, Ap. 70-264, 04510 DF (Mexico); Riera, A. [Departamento de Fisica e Ingenieria Nuclear, Escuela Universitaria de Ingenieria Tecnica Industrial de Barcelona, Universidad Politecnica de Cataluna, C. Comte Urgell 187, 08036, Barcelona (Spain); Beck, T. L., E-mail: ary@nucleares.unam.mx [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States)

    2012-03-15

    We present an analysis of H{alpha} spectra of the HH 34 jet with two-dimensional spectral resolution. We carry out multi-Gaussian fits to the spatially resolved line profiles and derive maps of the intensity, radial velocity, and velocity width of each of the components. We find that close to the outflow source we have three components: a high (negative) radial velocity component with a well-collimated, jet-like morphology; an intermediate velocity component with a broader morphology; and a positive radial velocity component with a non-collimated morphology and large linewidth. We suggest that this positive velocity component is associated with jet emission scattered in stationary dust present in the circumstellar environment. Farther away from the outflow source, we find only two components (a high, negative radial velocity component, which has a narrower spatial distribution than an intermediate velocity component). The fitting procedure was carried out with the new AGA-V1 code, which is available online and is described in detail in this paper.

  1. Modeling and experiment of the suspended seismometer concept for attenuating the contribution of tilt motion in horizontal measurements

    Science.gov (United States)

    Matichard, F.; Evans, M.; Mittleman, R.; MacInnis, M.; Biscans, S.; Dooley, K. L.; Sohier, H.; Lauriero, A.; Paris, H.; Koch, J.; Knothe, P.; Carbajo, A.; Dufort, C.

    2016-06-01

    Tilt-horizontal coupling in inertial sensors limits the performance of active isolation systems such as those used in gravitational wave detectors. Inertial rotation sensors can be used to subtract the tilt component from the signal produced by horizontal inertial sensors, but such techniques are often limited by the sensor noise of the tilt measurement. A different approach is to mechanically filter the tilt transmitted to the horizontal inertial sensor, as discussed in this article. This technique does not require an auxiliary rotation sensor and can produce a lower noise measurement. The concept investigated uses a mechanical suspension to isolate the inertial sensor from input tilt. Modeling and simulations show that such a configuration can be used to adequately attenuate the tilt transmitted to the instrument, while maintaining translation sensitivity in the frequency band of interest. The analysis is supported by experimental results showing that this approach is a viable solution to overcome the tilt problem in the field of active inertial isolation.

  2. Modeling and Experiment of the Suspended Seismometer Concept for Attenuating the Contribution of Tilt Motion in Horizontal Measurements

    CERN Document Server

    Matichard, F; Mittleman, R; McInnis, M; Biscans, S; Dooley, K L; Sohier, H; Lauriero, A; Paris, H; Koch, J; Knothe, P; Carbajo, A; Dufort, C

    2016-01-01

    Tilt-horizontal coupling in inertial sensors limits the performance of active isolation systems such as those used in gravitational wave detectors. Inertial rotation sensors can be used to subtract the tilt component from the signal produced by horizontal inertial sensors, but such techniques are often limited by the sensor noise of the tilt measurement. A different approach is to mechanically filter the tilt transmitted to the horizontal inertial sensor, as discussed in this article. This technique does not require an auxiliary rotation sensor, and can produce a lower noise measurement. The concept investigated uses a mechanical suspension to isolate the inertial sensor from input tilt. Modeling and simulations show that such a configuration can be used to adequately attenuate the tilt transmitted to the instrument, while maintaining translation sensitivity in the frequency band of interest. The analysis is supported by experimental results showing that this approach is a viable solution to overcome the tilt...

  3. Explorando nuevos horizontes en NASA

    Science.gov (United States)

    Villanueva, G. L.

    A pesar de la incesante expansión del Universo iniciada con el Big Bang 14 mil millones de años atrás, nuestro Universo se siente cada día más cercano. La inquebrantable vocación de la humanidad por descubrir nuevos horizontes ha permitido el acercamiento de civilizaciones en nuestro planeta y nos ha permitido conocer nuestro lugar en el Universo como nunca antes. En este artículo presento una breve sinopsis de nuestro trabajo que se relaciona con diversas investigaciones con implicaciones astrobiológicas, desde el origen de los ingredientes de la "sopa de la vida", hasta la evolución y composición de la atmósfera de Marte.

  4. EXPERIMENTAL AND NUMERICAL INVESTIGATIONS ON HORIZONTAL OIL-GAS FLOW

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Experiments were carried out to investigate the characteristics of oil-gas flow in a horizontal pipe on a large scale (with the inner diameter D = 125 mm). With the experimental data, the flow patterns were presented. Through the analyses for the flow regime transition, it was found that there was a critical superficial velocity of liquid phase for the flow regime transiting from stratified flow to slug flow. The slug flow could not occur until the superficial velocity of liquid phase was higher than the critical velocity. For the flow pattern transiting from stratified to slug flow, the transmitting velocity of gas phase decreases with the augmentation of superficial velocity of liquid phase. On the basis of the experiments, numerical simulations of different flow patterns and their transitions were performed with the use of the Volume Of Fluid (VOF) technique. The results of the computations are shown to match well with the measured data in the experiments.

  5. A new AMS facility based on a Cockcroft–Walton type 1 MV tandetron at IFIN-HH Magurele, Romania

    Energy Technology Data Exchange (ETDEWEB)

    Stan-Sion, C., E-mail: stansion@nipne.ro [Horia Hulubei National Institute of Physics and Nuclear Engineering (IFIN-HH), Bucharest (Romania); Enachescu, M.; Ghita, D.G.; Calinescu, C.I.; Petre, A.; Mosu, D.V. [Horia Hulubei National Institute of Physics and Nuclear Engineering (IFIN-HH), Bucharest (Romania); Klein, M. [High Voltage Engineering Europa B.V., Amsterdamsweg 63, 3812 RR Amersfoort P.O. Box 99, 3800 AB Amersfoort (Netherlands)

    2014-01-15

    A 1 MV AMS machine was recently installed in the National Institute for Physics and Nuclear Engineering IFIN-HH, Bucharest Romania. It is the second AMS facility at IFIN-HH having the goal not only to continue but mainly to enlarge the research area of this highly sensitive analyzing method. The multi-element AMS was developed by HVEE to measure {sup 14}C, {sup 10}Be, and {sup 26}Al, and {sup 129}I. The results of an acceptance test are presented and demonstrate that this machine is capable of routine {sup 14}C age dating and of measurements of other radioisotopes in terms of accuracy and precision as well as a low background level.

  6. Simulating Proton Synchrotron Radiation in the Arcs of the LHC, HL-LHC, and FCC-hh

    CERN Document Server

    Guillermo Cantón, Gerardo; Zimmermann, Frank

    2016-01-01

    At high proton-beam energies, beam-induced synchrotron radiation is an important source of heating, of beam-related vacuum pressure increase, and of primary photoelectrons, which can give rise to an electron cloud. We use the Synrad3D code developed at Cornell to simulate the photon distributions in the arcs of the LHC, HL-LHC, and FCC-hh. Specifically, for the LHC we study the effect of the “sawtooth” chamber, for the HL-LHC the consequences of the ATS optics with large beta beating in the arcs, and for the FCC-hh the effect of a novel beam-screen design, with a long slit surrounded by a “folded” antechamber.

  7. CAL3JHH: a Java program to calculate the vicinal coupling constants (3 J H,H) of organic molecules

    Science.gov (United States)

    Aguirre-Valderrama, Alonso; Dobado, José A.

    2008-12-01

    Here, we present a free web-accessible application, developed in the JAVA programming language for the calculation of vicinal coupling constant (3 J H,H) of organic molecules with the H-Csp3-Csp3-H fragment. This JAVA applet is oriented to assist chemists in structural and conformational analyses, allowing the user to calculate the averaged 3 J H,H values among conformers, according to its Boltzmann populations. Thus, the CAL3JHH program uses the Haasnoot-Leeuw-Altona equation, and, by reading the molecule geometry from a protein data bank (PDB) file format or from multiple pdb files, automatically detects all the coupled hydrogens, evaluating the data needed for this equation. Moreover, a "Graphical viewer" menu allows the display of the results on the 3D molecule structure, as well as the plotting of the Newman projection for the couplings.

  8. Similar sponge-associated bacteria can be acquired via both vertical and horizontal transmission.

    Science.gov (United States)

    Sipkema, Detmer; de Caralt, Sònia; Morillo, Jose A; Al-Soud, Waleed Abu; Sørensen, Søren J; Smidt, Hauke; Uriz, María J

    2015-10-01

    Marine sponges host diverse communities of microorganisms that are often vertically transmitted from mother to oocyte or embryo. Horizontal transmission has often been proposed to co-occur in marine sponges, but the mechanism is poorly understood. To assess the impact of the mode of transmission on the microbial assemblages of sponges, we analysed the microbiota in sympatric sponges that have previously been reported to acquire bacteria via either vertical (Corticium candelabrum and Crambe crambe) or horizontal transmission (Petrosia ficiformis). The comparative study was performed by polymerase chain reaction-denaturing gradient gel electrophoresis and pyrosequencing of barcoded PCR-amplified 16S rRNA gene fragments. We found that P. ficiformis and C. candelabrum each harbour their own species-specific bacteria, but they are similar to other high-microbial-abundance sponges, while the low-microbial-abundance sponge C. crambe hosts microbiota of a very different phylogenetic signature. In addition, nearly 50% of the reads obtained from P. ficiformis were most closely related to bacteria that were previously reported to be vertically transmitted in other sponges and comprised vertical-horizontal transmission phylogenetic clusters (VHT clusters). Therefore, our results provide evidence for the hypothesis that similar sponge-associated bacteria can be acquired via both vertical and horizontal transmission.

  9. INTERFEROMETRIC OBSERVATIONS OF NITROGEN-BEARING MOLECULAR SPECIES IN THE STAR-FORMING CORE AHEAD OF HH 80N

    Energy Technology Data Exchange (ETDEWEB)

    Masqué, Josep M.; Estalella, Robert [Departament d' Astronomia i Meteorologia, Universitat de Barcelona, Martí i Franquès 1, E-08028 Barcelona, Catalunya (Spain); Girart, Josep M. [Institut de Ciències de l' Espai (CSIC-IEEC), Campus UAB, Facultat de Ciències, Torre C5 - parell 2, E-08193 Bellaterra, Catalunya (Spain); Anglada, Guillem; Osorio, Mayra [Instituto de Astrofísica de Andalucía, CSIC, Camino Bajo de Huétor 50, E-18008 Granada (Spain); Beltrán, Maria T. [INAF-Osservatorio Astrofisico di Arcetri, Largo E. Fermi 5, I-50125 Firenze (Italy)

    2013-10-10

    We present Very Large Array NH{sub 3} and Plateau de Bure Interferometer NH{sub 2}D and HN{sup 13}C observations of the star-forming core ahead of HH 80N, the optically obscured northern counterpart of the Herbig-Haro objects HH 80/81. The main goal is to determine the kinematical information of the high density regions of the core (n ∼> 10{sup 5} cm{sup –3}) missed in previous works due to the depletion of the species observed (e.g., CS). The obtained maps show different kinematical signatures between the eastern and western parts of the core, suggesting a possible dynamical interaction of the core with the HH 80/81/80N outflow. The analysis of the position-velocity (P-V) plots of these species rules out a previous interpretation of having a molecular ring-like structure with a radius of 6 × 10{sup 4} AU traced by CS infalling onto a central protostar found in the core (IRS1). A high degree of NH{sub 3} deuteration, with respect to the central part of the core harboring IRS1, is derived in the eastern part, where a dust condensation (SE) is located. This deuteration trend of NH{sub 3} suggests that SE is in a pre-stellar evolutionary stage, earlier than that of IRS1. Since SE is the closest condensation to the HH 80N/81/80N outflow, in a case of outflow-core dynamical interaction, it should be perturbed first and be the most evolved condensation in the core. Therefore, the derived evolutionary sequence for SE and IRS1 makes outflow triggered star formation on IRS1 unlikely.

  10. Current challenges and future prospects for $\\gamma$ from $B\\to D hh^\\prime$ decays arXiv

    CERN Document Server

    Gershon, Tim

    Decays of the type $B\\to D hh^\\prime$, where a $b$~hadron decays to a neutral charm meson that can be an admixture of $D^0$ and $\\overline{D}{}^0$ states together with two light particles that are typically a kaon and a pion, have demonstrated potential to enable precise determinations of the angle $\\gamma$ of the CKM Unitarity Triangle. The current status and future prospects of these measurements are reviewed.

  11. Structure-guided mutational analysis of the OB, HhH, and BRCT domains of Escherichia coli DNA ligase.

    Science.gov (United States)

    Wang, Li Kai; Nair, Pravin A; Shuman, Stewart

    2008-08-22

    NAD(+)-dependent DNA ligases (LigAs) are ubiquitous in bacteria and essential for growth. LigA enzymes have a modular structure in which a central catalytic core composed of nucleotidyltransferase and oligonucleotide-binding (OB) domains is linked via a tetracysteine zinc finger to distal helix-hairpin-helix (HhH) and BRCT (BRCA1-like C-terminal) domains. The OB and HhH domains contribute prominently to the protein clamp formed by LigA around nicked duplex DNA. Here we conducted a structure-function analysis of the OB and HhH domains of Escherichia coli LigA by alanine scanning and conservative substitutions, entailing 43 mutations at 22 amino acids. We thereby identified essential functional groups in the OB domain that engage the DNA phosphodiester backbone flanking the nick (Arg(333)); penetrate the minor grove and distort the nick (Val(383) and Ile(384)); or stabilize the OB fold (Arg(379)). The essential constituents of the HhH domain include: four glycines (Gly(455), Gly(489), Gly(521), Gly(553)), which bind the phosphate backbone across the minor groove at the outer margins of the LigA-DNA interface; Arg(487), which penetrates the minor groove at the outer margin on the 3 (R)-OH side of the nick; and Arg(446), which promotes protein clamp formation via contacts to the nucleotidyltransferase domain. We find that the BRCT domain is required in its entirety for effective nick sealing and AMP-dependent supercoil relaxation.

  12. Digital media and sexually transmitted infections.

    Science.gov (United States)

    Gilliam, Melissa; Chor, Julie; Hill, Brandon

    2014-10-01

    Digital media, including the Internet, social networking sites, text messaging, and mobile applications, are ubiquitous among adolescents and young adults. These platforms enable users to obtain important information on a multitude of health topics, they may facilitate risk-taking behaviors, and they can be key components of health interventions. The purpose of this article is to review the recent literature on digital media and sexually transmitted infections, discussing their role in potentiating and reducing risk. This review demonstrates adolescents' use of digital media to gather information on health topics and discusses significant privacy concerns regarding using media to explore sexual health information. Although several studies demonstrate an association between social media and increased sexual risk-taking behaviors, this relationship is not fully understood. Digital media-based interventions are increasingly being developed to either reduce risk or improve management of sexually transmitted infections. As greater numbers of adolescents use digital media, the potential for these platforms to influence sexual risk-taking behaviors is significant. Additional research is needed to better understand the impact of digital media on sexually transmitted infection risk and to develop social media-based interventions to improve sexually transmitted infection outcomes.

  13. Zoonosis that is Transmitted Through Food

    Directory of Open Access Journals (Sweden)

    Tri Budhi Murdiati

    2006-03-01

    Full Text Available Zoonosis can be transmitted through a number of routes including food of animal products . Foodborne disease is a disease transmitted through food, while zoonosis is defined as a disease that can be transmitted from animal to man or vice versa . Then, if agent in foodborne disease is a zoonotic, it could be defined as foodborne zoonosis . The outbreaks of Bovine Spongioform Encephalopathy (BSE followed by Avian influenza (AI have caused increasing concern in the food safety of animal products, especially after men were confirmed die from Al infection . Consumers are wondering whether the disease could be transmitted through the animal products from the infected animals . The safety of animal originated food is affected by the practices along the food chain, from farm to consumer plate . Human health hazard could enter the food at any points of the food chain . At the food preparation, some of the foodborne zoonosis can be prevented by the program of five keys for safer food, i .e. keep food clean, separate raw from cooked food, cook food thoroughly, store food at safe temperatures and use water and raw materials that are safe .

  14. Inductive Reasoning about Causally Transmitted Properties

    Science.gov (United States)

    Shafto, Patrick; Kemp, Charles; Bonawitz, Elizabeth Baraff; Coley, John D.; Tenenbaum, Joshua B.

    2008-01-01

    Different intuitive theories constrain and guide inferences in different contexts. Formalizing simple intuitive theories as probabilistic processes operating over structured representations, we present a new computational model of category-based induction about causally transmitted properties. A first experiment demonstrates undergraduates'…

  15. Optimization of horizontal well staggered patterns

    Institute of Scientific and Technical Information of China (English)

    Zhao Chunsen; Li Peijing; Guan Dan; Liu Qingjuan

    2008-01-01

    Staggered line-drive patterns are widely used in oilfields. In this paper, to optimize a staggered pattern of horizontal wells, a 3D problem was divided into two 2D (x-y plane and y-z plane) problems with the pseudo-3D method, conformal transformation and superposition principle. A productivity equation for a horizontal well was deduced, which can be used to optimize the well pattern. A relationship between the length of horizontal wells and the shape factor of well patterns was established. The result shows that optimized well patterns can improve oil production from horizontal wells. This provides a theoretical basis for horizontal well applications to the development of oilfieids, especially for overall development of oilfields by horizontal wells.

  16. X-RAY EMISSION FROM STELLAR JETS BY COLLISION AGAINST HIGH-DENSITY MOLECULAR CLOUDS: AN APPLICATION TO HH 248

    Energy Technology Data Exchange (ETDEWEB)

    López-Santiago, J.; Ustamujic, S.; Castro, A. I. Gómez de [S. D. Astronomía y Geodesia, Facultad de Ciencias Matemáticas, Universidad Complutense de Madrid, E-28040 Madrid (Spain); Bonito, R.; Orlando, S. [Dipartimento di Fisica e Chimica, Università di Palermo, Piazza del Parlamento 1, I-90134 Palermo (Italy); Orellana, M. [Sede Andina de la Universidad Nacional de Río Negro (Argentina); Miceli, M. [INAF-Osservatorio Astronomico di Palermo, Piazza del Parlamento 1, I-90134 Palermo (Italy); Albacete-Colombo, J. F. [Sede Atlántica de la Universidad Nacional de Río Negro, Don Bosco y Leloir s/n, 8500 Viedma RN (Argentina); Castro, E. de [Dpto. de Astrofísica y CC. de la Atmósfera, Facultad de Física, Universidad Complutense de Madrid, E-28040 Madrid (Spain)

    2015-06-10

    We investigate the plausibility of detecting X-ray emission from a stellar jet that impacts a dense molecular cloud, a scenario that may be typical for classical T Tauri stars with jets in dense star-forming complexes. We first model the impact of a jet against a dense cloud using two-dimensional axisymmetric hydrodynamic simulations, exploring different configurations of the ambient environment. Then, we compare our results with XMM-Newton observations of the Herbig–Haro object HH 248, where extended X-ray emission aligned with the optical knots is detected at the edge of the nearby IC 434 cloud. Our simulations show that a jet can produce plasma with temperatures up to 10{sup 7} K, consistent with production of X-ray emission, after impacting a dense cloud. We find that jets denser than the ambient medium but less dense than the cloud produce detectable X-ray emission only at impact with the cloud. From an exploration of the model parameter space, we constrain the physical conditions (jet density and velocity and cloud density) that reproduce the intrinsic luminosity and emission measure of the X-ray source possibly associated with HH 248 well. Thus, we suggest that the extended X-ray source close to HH 248 corresponds to a jet impacting a dense cloud.

  17. A rotating molecular disk toward IRAS 18162-2048, the exciting source of HH 80-81

    CERN Document Server

    Fernández-López, M; Curiel, Salvador; Gómez, Yolanda; Ho, Paul T P; Patel, Nimesh

    2011-01-01

    We present several molecular line emission arcsec and subarcsec observations obtained with the Submillimeter Array (SMA) in the direction of the massive protostar IRAS 18162-2048, the exciting source of HH 80-81. The data clearly indicates the presence of a compact (radius~425-850 AU) SO2 structure, enveloping the more compact (radius~150 AU) 1.4 millimeter dust emission (reported in a previous paper). The emission spatially coincides with the position of the prominent thermal radio jet which terminates at the HH 80-81 and HH 80N Herbig-Haro objects. Furthermore, the molecular emission is elongated in the direction perpendicular to the axis of the thermal radio jet, suggesting a disk-like structure. We derive a total dynamic mass (disk-like structure and protostar) of 11-15 msun. The SO2 spectral line data also allow us to constrain the structure temperature between 120-160 K and the volume density \\geq 2 \\times 10^9 cm3. We also find that such a rotating flattened system could be unstable due to gravitationa...

  18. Accurate quantum thermal rate constants for the three-dimensional H+H2 reaction

    Science.gov (United States)

    Park, Tae Jun; Light, J. C.

    1989-07-01

    The rate constants for the three-dimensional H+H2 reaction on the Liu-Siegbahn-Truhlar-Horowitz (LSTH) surface are calculated using Pack-Parker hyperspherical (APH) coordinates and a C2v symmetry adapted direct product discrete variable representation (DVR). The C2v symmetry decomposition and the parity decoupling on the basis are performed for the internal coordinate χ. The symmetry decomposition results in a block diagonal representation of the flux and Hamiltonian operators. The multisurface flux is introduced to represent the multichannel reactive flux. The eigenvalues and eigenvectors of the J=0 internal Hamiltonian are obtained by sequential diagonalization and truncation. The individual symmetry blocks of the flux operator are propagated by the corresponding blocks of the Hamiltonian, and the J=0 rate constant k0(T) is obtained as a sum of the rate constants calculated for each block. k0(T) is compared with the exact k0(T) obtained from thermal averaging of the J=0 reaction probabilities; the errors are within 5%-20% up to T=1500 K. The sequential diagonalization-truncation method reduces the size of the Hamiltonian greatly, but the resulting Hamiltonian matrix still describes the time evolution very accurately. For the J≠0 rate constant calculations, the truncated internal Hamiltonian eigenvector basis is used to construct reduced (JKJ) blocks of the Hamiltonian. The individual (JKJ) blocks are diagonalized neglecting Coriolis coupling and treating the off-diagonal KJ±2 couplings by second order perturbation theory. The full wave function is parity decoupled. The rate constant is obtained as a sum over J of (2J+1)kJ(T). The time evolution of the flux for J≠0 is again very accurately described to give a well converged rate constant.

  19. Late-Type Near-Contact Eclipsing Binary [HH97] FS Aur-79

    Science.gov (United States)

    Austin, S. J.; Robertson, J. W.; Tycner, C.; Campbell, T.; Honeycutt, R. K.

    2007-05-01

    The secondary photometric standard star number 79 for the FS Aur field (Henden & Honeycutt 1997), designated as [HH97] FS Aur-79 (GSC 1874-399), is a short-period (0.2508 days) eclipsing binary whose light curve is a combination of the β Lyr and BY Dra type variables. High signal-to-noise ratio multicolor photometry was obtained using the US Naval Observatory 1 m telescope. These light curves show asymmetry at quadrature phases (the O'Connell effect), which can be modeled with the presence of starspots. A low-resolution spectrum obtained with the 3.5 m Wisconsin-Indiana-Yale-NOAO telescope at orbital phase 0.76 is consistent with a spectral type of dK7e and dM3e. A radial velocity curve for the primary star was constructed using 24 high-resolution spectra from the 9.2 m Hobby-Eberly Telescope. Spectra show Hα and Hβ in emission confirming chromospheric activity and possibly the presence of circumstellar material. Binary star models that simultaneously fit the U, B, V, R, and radial velocity curves are those with a primary star of mass 0.59+/-0.02 Msolar, temperature 4100+/-25 K, and mean radius 0.67 Rsolar, just filling its Roche lobe, and a secondary star of mass 0.31+/-0.09 Msolar, temperature 3425+/-25 K, and mean radius 0.48 Rsolar, just within its Roche lobe. An inclination angle of 83deg+/-2deg with a center-of-mass separation of 1.62 Rsolar is also derived. Starspots, expected for a rotation period of less than 1 day, had to be included in the modeling to fit the O'Connell effect.

  20. Modulation of host immunity and reproduction by horizontally acquired Wolbachia.

    Science.gov (United States)

    Pigeault, Romain; Braquart-Varnier, Christine; Marcadé, Isabelle; Mappa, Gaëtan; Mottin, Elmina; Sicard, Mathieu

    2014-11-01

    The Wolbachia are symbiotic bacteria vertically transmitted from one host generation to another. However, a growing amount of data shows that horizontal transfers of Wolbachia also frequently occur within and between host species. The consequences of the arrival of new symbionts on host physiology can be studied by their experimental introduction in asymbiotic hosts. After experimental transfers of the eight major isopod Wolbachia strains in the isopod Porcellio dilatatus only two of them (wCon and wDil) were found to (1) have no pathogenic effect on the host and (2) be able to pass vertically to the host offspring. In the present work, we studied the influence of these two strains, able to complete an horizontal transfer, on immunity and reproduction of P. dilatatus at two stages of the transfer: (1) in recipient hosts that encounter the symbionts: to test the influence of symbiont when acquired during host life and (2) in vertically infected offspring: to test the influence of a symbiotic interaction occurring all lifelong. The impact of Wolbachia varied depending on the stage: there were clearer effects in vertically infected individuals than in those that acquired the symbionts during their lives. Moreover, the two Wolbachia strains showed contrasted effects: the strain wCon tended to reduce the reproductive investment but to maintain or increase immune parameters whilst wDil had positive effects on reproductive investment but decreased the investment in some immune parameters. These results suggest that horizontally acquisition of Wolbachia can influence the balance between host immune and reproductive traits.

  1. Widespread horizontal transfer of retrotransposons.

    Science.gov (United States)

    Walsh, Ali Morton; Kortschak, R Daniel; Gardner, Michael G; Bertozzi, Terry; Adelson, David L

    2013-01-15

    In higher organisms such as vertebrates, it is generally believed that lateral transfer of genetic information does not readily occur, with the exception of retroviral infection. However, horizontal transfer (HT) of protein coding repetitive elements is the simplest way to explain the patchy distribution of BovB, a long interspersed element (LINE) about 3.2 kb long, that has been found in ruminants, marsupials, squamates, monotremes, and African mammals. BovB sequences are a major component of some of these genomes. Here we show that HT of BovB is significantly more widespread than believed, and we demonstrate the existence of two plausible arthropod vectors, specifically reptile ticks. A phylogenetic tree built from BovB sequences from species in all of these groups does not conform to expected evolutionary relationships of the species, and our analysis indicates that at least nine HT events are required to explain the observed topology. Our results provide compelling evidence for HT of genetic material that has transformed vertebrate genomes.

  2. On the Hydraulics of Flowing Horizontal Wells

    Science.gov (United States)

    Bian, A.; Zhan, H.

    2003-12-01

    A flowing horizontal well is a special type of horizontal well that does not have pumping/injecting facility. The discharge rate of a flowing horizontal well is controlled by the hydraulic gradient between the aquifer and the well and it generally varies with time if the hydraulic head of the aquifer is transient. This type of well has been used in landslide control, mining dewatering, water table control, underground water transportation through a horizontal tunnel, agricultural water drainage, and other applications. Flowing horizontal wells have quite different hydrodynamic characteristics from horizontal wells with fixed pumping or injecting rates because their discharge rates are functions of the aquifer hydraulic heads (Zhan et al, 2001; Zhan and Zlotnik, 2002). Hydraulics of flowing horizontal wells have rarely been studied although the hydraulics of flowing vertical wells have been extensively investigated before. The purpose of this paper is to obtain analytical solutions of groundwater flow to a flowing horizontal-well in a confined aquifer, in a water table aquifer without precipitation, and in a water table aquifer with precipitation. The functions of the flowing horizontal well discharge rates versus time will be obtained under above mentioned different aquifer conditions. The relationships of the aquifer hydraulic heads versus the discharge rates of the well will be investigated. The rate of water table decline due to the dewatering of the well will also be computed, and this solution is particularly useful for landslide control and mining dewatering. The theoretical solutions will be compared with results of experiments that will be conducted in the hydrological laboratory at Texas A&M University. Reference: Zhan, H., Wang, L.V., and Park, E, On the horizontal well pumping tests in the anisotropic confined aquifers, J. hydrol., 252, 37-50, 2001. Zhan, H., and Zlotnik, V. A., Groundwater flow to a horizontal or slanted well in an unconfined aquifer

  3. Atomic Hydrogen Surrounded by Water Molecules, H(H2O)m, Modulates Basal and UV-Induced Gene Expressions in Human Skin In Vivo

    Science.gov (United States)

    Shin, Mi Hee; Park, Raeeun; Nojima, Hideo; Kim, Hyung-Chel; Kim, Yeon Kyung; Chung, Jin Ho

    2013-01-01

    Recently, there has been much effort to find effective ingredients which can prevent or retard cutaneous skin aging after topical or systemic use. Here, we investigated the effects of the atomic hydrogen surrounded by water molecules, H(H2O)m, on acute UV-induced responses and as well as skin aging. Interestingly, we observed that H(H2O)m application to human skin prevented UV-induced erythema and DNA damage. And H(H2O)m significantly prevented UV-induced MMP-1, COX-2, IL-6 and IL-1β mRNA expressions in human skin in vivo. We found that H(H2O)m prevented UV-induced ROS generation and inhibited UV-induced MMP-1, COX-2 and IL-6 expressions, and UV-induced JNK and c-Jun phosphorylation in HaCaT cells. Next, we investigated the effects of H(H2O)m on intrinsically aged or photoaged skin of elderly subjects. In intrinsically aged skin, H(H2O)m application significantly reduced constitutive expressions of MMP-1, IL-6, and IL-1β mRNA. Additionally, H(H2O)m significantly increased procollagen mRNA and also decreased MMP-1 and IL-6 mRNA expressions in photoaged facial skin. These results demonstrated that local application of H(H2O)m may prevent UV-induced skin inflammation and can modulate intrinsic skin aging and photoaging processes. Therefore, we suggest that modifying the atmospheric gas environment within a room may be a new way to regulate skin functions or skin aging. PMID:23637886

  4. Simultaneous Overexpression of the HhERF2 and PeDREB2a Genes Enhanced Tolerances to Salt and Drought in Transgenic Cotton.

    Science.gov (United States)

    Li, Jin Bo; Ni Dong, Xue; Lei, Zhi; Liang Li, Yong; Yang Yang, Pei; Tao, Fei; Zhao, Liang; Li, Shi-Gang; Du, Lin Feng; Shao, Ji Rong; Wu, Yan Min

    2016-01-01

    A desert-grown Halimodendron halodendron ethylene-responsive element binding factor gene (HhERF2), which encodes a 245 amino acids protein containing a conserved AP2/EREBP domain, was isolated through the rapid amplification cDNA end (RACE) method. Sequence and phylogenetic analysis indicated that HhERF2 was classified into the B-2 group of ERF subfamily. Semiquantitative RT-PCR showed that HhERF2 was greatly induced by treatments with high-salt, drought and low temperature in H. halodendron seedlings. The expression vector containing HhERF2 and Populus euphratica dehydration- responsive element binding protein (PeDREB2a) genes driven by rd29A promoter was constructed and transferred into cotton (Gossypium hirsutum L.) by non-tissue culture Agrobacterium-mediated genetic transformation system. The transformation and expression of HhERF2 and PeDREB2a were identified by PCR and RT-PCR. Analyses of physiological function indicated that transgenic cottons had improved seeds germination, tolerance to drought and highsalt stresses. Agronomic evaluation in the field exhibited that transgenic lines presented a dwarf phenotype and improved further in the yield and characters. These results demonstrated that overexpressed both HhERF2 and PeDREB2a transcription factor genes in cotton induced elevated tolerance to drought and high-salt stresses.

  5. Horizontal Directional Drilling (HDD) Technology and Applications

    Institute of Scientific and Technical Information of China (English)

    J. G. Cai; X. N. Wang

    2004-01-01

    @@ 1 What is Horizontal Directional Drilling? Horizontal Directional Drilling, accurately steered drilling, has become state -of- the -art drilling technique in the world. Specially- designed directionsteerable corebarrel and accurate direction measurement tool are available for the use together with wire line core drilling machine. That makes it feasible to extract cores and to measure the drill travel line &length while drilling in a curve.

  6. Advances in understanding paternally transmitted Chromosomal Abnormalities

    Energy Technology Data Exchange (ETDEWEB)

    Marchetti, F; Sloter, E; Wyrobek, A J

    2001-03-01

    Multicolor FISH has been adapted for detecting the major types of chromosomal abnormalities in human sperm including aneuploidies for clinically-relevant chromosomes, chromosomal aberrations including breaks and rearrangements, and other numerical abnormalities. The various sperm FISH assays have been used to evaluate healthy men, men of advanced age, and men who have received mutagenic cancer therapy. The mouse has also been used as a model to investigate the mechanism of paternally transmitted genetic damage. Sperm FISH for the mouse has been used to detect chromosomally abnormal mouse sperm, while the PAINT/DAPI analysis of mouse zygotes has been used to evaluate the types of chromosomal defects that can be paternally transmitted to the embryo and their effects on embryonic development.

  7. SEXUALLY TRANSMITTED DISEASES: INCIDENCE AND DISTRIBUTION

    Institute of Scientific and Technical Information of China (English)

    王千秋

    1996-01-01

    The incidence of sexually transmitted diseases(STDs) increased from 26. 04 per 10000O in 1987 to 104. 81 per 100 000 in 1993 in selected areas of the country. Gonorrhea is by far the most common STD but its constituent ratio declined because of a rapid increase of nongonococcal uretheritis and genital warts during most recent years. The incidence of syphilis is relatively low and cases of congenital infection are noted. The wide spread of resistant Neisseria gonorrhaeae infection gives a challenge to the therapeutical and control strategies of STDs. Sexually transmitted Chlamydia trachomatis infections, an important cause of urethritis, cervicitis and pelvic inflammatory disease, is becoming common in uur country. Attention has been drawn on viral hepatitis in their means of transmission by sexually behaviors, and also, on the homosexuals, assumed to be the high risk group to catch STDs. Coordinated national efforts to control STDs in China have been taken.

  8. Syndromes Associated with Sexually Transmitted Infections

    OpenAIRE

    Max Chernesky; David Patrick; Rosanna Peeling

    2005-01-01

    Excellent technologies have been developed to identify the specific microbial agents of chlamydia, gonorrhea, syphilis, herpes, chancroid, trichomoniasis, human papillomavirus and HIV infection. However, it is also crucial to recognize syndromes that may be caused by one or more sexually transmitted pathogens. When laboratory services are lacking or are inadequate to provide timely results to enable appropriate treatment, some patients must be managed and treated syndromically. Most Canadian ...

  9. Molecular Diagnostics for Soil-Transmitted Helminths

    OpenAIRE

    O'Connell, Elise M.; Nutman, Thomas B.

    2016-01-01

    Historically, the diagnosis of soil-transmitted helminths (STHs) (e.g., Strongyloides stercoralis, Trichuris trichiura, Ancylostoma duodenale, Necator americanus, and Ascaris lumbricoides) has relied on often-insensitive microscopy techniques. Over the past several years, there has been an effort to use molecular diagnostics, particularly quantitative polymerase chain reaction (qPCR), to detect intestinal pathogens. While some platforms have been approved by regulatory bodies (e.g., Food and ...

  10. Intra-firm Horizontal Knowledge Transfer Management

    Institute of Scientific and Technical Information of China (English)

    WANG Yaowu; WANG Yanhang

    2009-01-01

    Knowledge transfer is widely emphasized as a strategic issue for firm competition. A model for intra-firm horizontal knowledge transfer is proposed to model horizontal knowledge transfer to solve some demerits in current knowledge transfer researches. The concept model of intra-firm horizontal knowledge transfer was described and a framework was provided to define the main components of thetransfer process. Horizontal knowledge transfer is that knowledge is transferred from the source to the same hierarchical level recipients as the target. Horizontal knowledge transfer constitutes a strategic area of knowledge management research. However, little is known about the circumstances under which one particular mechanism is the most appropriate. To address these issues, some significant conclusions are drawn concerning knowledge transfer mechanisms in a real-world setting.

  11. Horizontal Canal Benign Positional Vertigo

    Directory of Open Access Journals (Sweden)

    Mohtaram Najafi

    1998-03-01

    Full Text Available Benign paroxysmal positional vertigo (BPPV is a syndrome characterized by transient episodes of vertigo in association with rapid changes in head position in Dix-Halpike Maneuver. This kind of vertigo is thought to be caused by migration of otoconial debris into canals other than the posterior canal, such as the anterior or lateral canals. It is also theoretically possible for many aberrant patterns of BPPV to occur from an interaction of debris in several canals, location of debris within the canal, and central adaptation patterns to lesions. The symptoms of BPPV are much more consistent with free-moving densities (canaliths in the posterior SCC rather than fixed densities attached to the cupula. While the head is upright, the particles sit in the PSC at the most gravity-dependent position. The best method to induce and see vertigo and nystagmus in BPPV of the lateral semicircular canal is to rotate head 90°while patient is in the supine position, nystagmus would appear in the unaffected side weaker but longer than the affected side. canal paresis has been described in one third of the patients with BPPV. Adaptation which is one of the remarkable features of BPPV in PSC is rarely seen in LSC. Rotations of 270° or 360° around the yaw axis (the so-called barbecue maneuver toward the unaffected ear are popular methods for the treatment of geotropic HC-BPPV. These maneuvers consist of sequential head turning of 90° toward the healthy side while supine. With these maneuvers, the free-floating otoconial debris migrates in the ampullofugal direction, finally entering the utricle through the nonampullated end of the horizontal canal. This kind of vertigo recovers spontaneously more rapidly and suddenly.

  12. Directional, horizontal inhomogeneities of cloud optical thickness fields retrieved from ground-based and airbornespectral imaging

    Science.gov (United States)

    Schäfer, Michael; Bierwirth, Eike; Ehrlich, André; Jäkel, Evelyn; Werner, Frank; Wendisch, Manfred

    2017-02-01

    Clouds exhibit distinct horizontal inhomogeneities of their optical and microphysical properties, which complicate their realistic representation in weather and climate models. In order to investigate the horizontal structure of cloud inhomogeneities, 2-D horizontal fields of optical thickness (τ) of subtropical cirrus and Arctic stratus are investigated with a spatial resolution of less than 10 m. The 2-D τ-fields are derived from (a) downward (transmitted) solar spectral radiance measurements from the ground beneath four subtropical cirrus and (b) upward (reflected) radiances measured from aircraft above 10 Arctic stratus. The data were collected during two field campaigns: (a) Clouds, Aerosol, Radiation, and tuRbulence in the trade wind regime over BArbados (CARRIBA) and (b) VERtical Distribution of Ice in Arctic clouds (VERDI). One-dimensional and 2-D autocorrelation functions, as well as power spectral densities, are derived from the retrieved τ-fields. The typical spatial scale of cloud inhomogeneities is quantified for each cloud case. Similarly, the scales at which 3-D radiative effects influence the radiance field are identified. In most of the investigated cloud cases considerable cloud inhomogeneities with a prevailing directional structure are found. In these cases, the cloud inhomogeneities favour a specific horizontal direction, while across this direction the cloud is of homogeneous character. The investigations reveal that it is not sufficient to quantify horizontal cloud inhomogeneities using 1-D inhomogeneity parameters; 2-D parameters are necessary.

  13. Effects of reverse waves on the hydrodynamic pressure acting on a dual porous horizontal plate

    Directory of Open Access Journals (Sweden)

    Kweon Hyuck-Min

    2014-03-01

    Full Text Available The seaward reverse wave, occurring on the submerged dual porous horizontal plate, can contribute to the reduction of the transmitted wave as it reflects the propagating wave. However, the collision between the propa¬gating and seaward reverse waves increases the water level and acts as a weight on the horizontal plate. This study investigated the characteristics of the wave pressure created by the seaward reverse wave through the analysis of expe¬rimental data. The analysis confirmed the following results: 1 the time series of the wave pressure showed reverse phase phenomena due to the collision, and the wave pressures acted simultaneously on both upper and lower surfaces of the horizontal plate; 2 the horizontal plate became repeatedly compressed and tensile before and after the occur¬rence of the seaward reverse wave; and 3 the seaward reverse wave created the total wave pressure to the maximum towards the direction of gravity, primarily on the upper plate. It was also confirmed that the wave distributions showed a similar trend to the wave steepness. Such outcome of the analysis will provide basic information to the structural analysis of the horizontal plate as a wave dissipater of the steel-type breakwater (STB.

  14. HH 666: different kinematics from H α and [Fe II] emission provide a missing link between jets and outflows

    Science.gov (United States)

    Reiter, Megan; Smith, Nathan; Kiminki, Megan M.; Bally, John

    2015-06-01

    HH 666 is an externally irradiated protostellar outflow in the Carina nebula for which we present new near-IR [Fe II] spectra obtained with the Folded-Port Infrared Echellette spectrograph at Magellan Observatory. Earlier H α and near-IR [Fe II] imaging revealed that the two emission lines trace substantially different morphologies in the inner ˜40 arcsec of the outflow. H α traces a broad cocoon that surrounds the collimated [Fe II] jet that extends throughout the parent dust pillar. New spectra show that this discrepancy extends to their kinematics. Near-IR [Fe II] emission traces steady, fast velocities of ±200 km s-1 from the eastern and western limbs of the jet. We compare this to a previously published H α spectrum that reveals a Hubble-flow velocity structure near the jet-driving source. New, second-epoch Hubble Space Telescope (HST)/Advanced Camera for Surveys (ACS) H α images reveal the lateral spreading of the H α outflow lobe away from the jet axis. H α proper motions also indicate a sudden increase in the mass-loss rate ˜1000 yr ago, while steady [Fe II] emission throughout the inner jet suggest that the burst is ongoing. An accretion burst sustained for ˜1000 yr is an order of magnitude longer than expected for FU Orionis outbursts, but represents only a small fraction of the total age of the HH 666 outflow. Altogether, available data suggests that [Fe II] traces the highly collimated protostellar jet while H α traces the entrained and irradiated outflow. HH 666 appears to be a missing link between bare jets seen in H II regions and entrained molecular outflows seen from embedded protostars in more quiescent regions.

  15. Optimizing of Culture Conditionin Horizontal Rotating Bioreactor

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    1 IntroductionBioreactor is the most important equipment in tissue engineering. It can mimic the micro-environment of cell growth in vitro. At present, horizontal rotating bioreactor is the most advanced equipment for cell culture in the world. 2 Rotating bioreactors2.1 Working principleThere are two kinds of horizontal rotating bioreactor: HARV(high aspect ratio vessel) and RCCS (rotary cell culture system). It is drived by step motor with horizontal rotation, the culture medium and cell is filled between ...

  16. Stochastic dynamics for reinfection by transmitted diseases

    Science.gov (United States)

    Barros, Alessandro S.; Pinho, Suani T. R.

    2017-06-01

    The use of stochastic models to study the dynamics of infectious diseases is an important tool to understand the epidemiological process. For several directly transmitted diseases, reinfection is a relevant process, which can be expressed by endogenous reactivation of the pathogen or by exogenous reinfection due to direct contact with an infected individual (with smaller reinfection rate σ β than infection rate β ). In this paper, we examine the stochastic susceptible, infected, recovered, infected (SIRI) model simulating the endogenous reactivation by a spontaneous reaction, while exogenous reinfection by a catalytic reaction. Analyzing the mean-field approximations of a site and pairs of sites, and Monte Carlo (MC) simulations for the particular case of exogenous reinfection, we obtained continuous phase transitions involving endemic, epidemic, and no transmission phases for the simple approach; the approach of pairs is better to describe the phase transition from endemic phase (susceptible, infected, susceptible (SIS)-like model) to epidemic phase (susceptible, infected, and removed or recovered (SIR)-like model) considering the comparison with MC results; the reinfection increases the peaks of outbreaks until the system reaches endemic phase. For the particular case of endogenous reactivation, the approach of pairs leads to a continuous phase transition from endemic phase (SIS-like model) to no transmission phase. Finally, there is no phase transition when both effects are taken into account. We hope the results of this study can be generalized for the susceptible, exposed, infected, and removed or recovered (SEIRIE) model, for which the state exposed (infected but not infectious), describing more realistically transmitted diseases such as tuberculosis. In future work, we also intend to investigate the effect of network topology on phase transitions when the SIRI model describes both transmitted diseases (σ 1 ).

  17. CMA Performance in CDMA Transmit Diversity System

    Institute of Scientific and Technical Information of China (English)

    ZHAO Jing-hua; FENG Guang-zeng

    2005-01-01

    Plenty of work have been done on Space-Time processing in which multiple transmit/receive antennas are used in conjunction with coding to exploit both spatial diversity and time diversity. Constant Mode Algorithm (CMA) is an efficient blind adaptive Multi-User Detection (MUD) algorithm for CDMA systems. In this paper, we put forward a novel receiver, which combines CMA blind adaptive Multi-user Detection with STBC technique, and compare the performances of the system using different CM algorithms including SDCMA (Steepest-Descent CMA), Standard Linearity Confine CMA(SLCCMA) and Least Squares CMA(LSCMA). Simulations have been done with multi-path Rayleigh channel.

  18. Hydrostatic limits of 11 pressure transmitting media

    Science.gov (United States)

    Klotz, S.; Chervin, J.-C.; Munsch, P.; LeMarchand, G.

    2009-04-01

    We present a systematic and comparative study of the pressure-induced solidification of 11 frequently used pressure transmitting fluids using the ruby fluorescence technique in a diamond anvil cell. These fluids are 1 : 1 and 5 : 1 iso-n pentane, 4 : 1 deuterated methanol-ethanol, 16 : 3 : 1 deuterated methanol-ethanol-water, 1 : 1 FC84-FC87 Fluorinert, Daphne 7474, silicone oil, as well as nitrogen, neon, argon and helium. The data provide practical guidelines for the use of these fluids in high pressure experiments up to 50 GPa.

  19. Reducing Transmitted Vibration Using Delayed Hysteretic Suspension

    Directory of Open Access Journals (Sweden)

    Lahcen Mokni

    2011-01-01

    Full Text Available Previous numerical and experimental works show that time delay technique is efficient to reduce transmissibility of vibration in a single pneumatic chamber by controlling the pressure in the chamber. The present work develops an analytical study to demonstrate the effectiveness of such a technique in reducing transmitted vibrations. A quarter-car model is considered and delayed hysteretic suspension is introduced in the system. Analytical predictions based on perturbation analysis show that a delayed hysteretic suspension enhances vibration isolation comparing to the case where the nonlinear damping is delay-independent.

  20. Discourse on the values transmitted in universities Uganda ...

    African Journals Online (AJOL)

    Discourse on the values transmitted in universities Uganda. ... suitability of the knowledge and values offered in African universities has been a matter ... It was found that material, social/ public, personal and religious values are transmitted to ...

  1. Common Culex Mosquitoes Don't Transmit Zika Virus

    Science.gov (United States)

    ... 161186.html Common Culex Mosquitoes Don't Transmit Zika Virus: Study These widespread insects do spread West Nile ... t appear to be able to transmit the Zika virus to people, researchers report. The researchers at Kansas ...

  2. 铁过载引发人肝细胞HH4 N-糖链表达差异研究%Study on differential expression of N-linked glycans in iron overload-induced human hepatocytes HH4

    Institute of Scientific and Technical Information of China (English)

    李士伟; 关锋; 李想

    2015-01-01

    Hepatic iron overload is common in patients undergoing hematopoietic cell transplantation and may be associated with hepatic injury. Here iron overload model of HH4 cells induced by FAC (ferric ammonium citrate) was established. The total proteins of HH4 cells treated with or without FAC were extracted, and total glycopeptides were isolated by an ultrafiltration unit. The glycopeptides were enzymatically hydrolyzed by Peptide-N-glycosidase F (PNGase F) and the released N-linked glycans were desalinated using Sepharose 4B. The structures of the purified N-glycans were identified by matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF/TOF-MS). Furthermore, the comparative expression of N-glycans was analyzed by lectin immunohistochemistry. The result indicated that 16 N-glycans were differentially expressed in HH4 cells treated with or without FAC. The levels of high-mannose-type N-glycans were decreased significantly, while the expression of hybrid type, complex type, bisecting type, fucosylation and sialylation of glycans were enhanced markedly in FAC-treated HH4 cells. Consistent with MS analysis, lectin immunohistochemistry study showed that the binding affinity to lectin ConA was reduced in FAC-treated HH4 cells, but the binding affinities to 4 lectins PHA-E, AAL, LCA and MAL-II were significantly increased. The present research provides the fundamental observations for further understanding functional roles of differential expression of N-linked glycans in iron-overload HH4 cells.%肝脏铁过载是血液系统疾病患者进行骨髓移植后的典型并发症之一,长期铁过载可引发肝脏细胞凋亡和器官损坏,然而铁过载的分子调控机理迄今仍不清楚。以培养的枸橼酸铁铵过载人肝细胞HH4和正常人肝细胞HH4为研究对象,细胞裂解提取总蛋白,分子筛超滤管分离获得总糖肽,PNGase F酶解释放出N-糖链,Sepharose 4B除盐纯化N-糖链,再利用基质

  3. Horizontal cooperation in transport and logistics

    NARCIS (Netherlands)

    Cruijssen, F.C.A.M.

    2006-01-01

    This thesis deals with horizontal cooperation in transport and logistics. It contains a comprehensive discussion of the available academic literature on this topic, many practical examples, and an empirical investigation of opportunities and impediments. Furthermore, three enabling concepts for

  4. Sexually transmitted diseases treatment guidelines, 2015.

    Science.gov (United States)

    Workowski, Kimberly A; Bolan, Gail A

    2015-06-05

    These guidelines for the treatment of persons who have or are at risk for sexually transmitted diseases (STDs) were updated by CDC after consultation with a group of professionals knowledgeable in the field of STDs who met in Atlanta on April 30-May 2, 2013. The information in this report updates the Sexually Transmitted Diseases Treatment Guidelines, 2010 (MMWR Recomm Rep 2010;59 [No. RR-12]). These updated guidelines discuss 1) alternative treatment regimens for Neisseria gonorrhoeae; 2) the use of nucleic acid amplification tests for the diagnosis of trichomoniasis; 3) alternative treatment options for genital warts; 4) the role of Mycoplasma genitalium in urethritis/cervicitis and treatment-related implications; 5) updated HPV vaccine recommendations and counseling messages; 6) the management of persons who are transgender; 7) annual testing for hepatitis C in persons with HIV infection; 8) updated recommendations for diagnostic evaluation of urethritis; and 9) retesting to detect repeat infection. Physicians and other health-care providers can use these guidelines to assist in the prevention and treatment of STDs.

  5. Sexually transmitted diseases treatment guidelines, 2010.

    Science.gov (United States)

    Workowski, Kimberly A; Berman, Stuart

    2010-12-17

    These guidelines for the treatment of persons who have or are at risk for sexually transmitted diseases (STDs) were updated by CDC after consultation with a group of professionals knowledgeable in the field of STDs who met in Atlanta on April 18-30, 2009. The information in this report updates the 2006 Guidelines for Treatment of Sexually Transmitted Diseases (MMWR 2006;55[No. RR-11]). Included in these updated guidelines is new information regarding 1) the expanded diagnostic evaluation for cervicitis and trichomoniasis; 2) new treatment recommendations for bacterial vaginosis and genital warts; 3) the clinical efficacy of azithromycin for chlamydial infections in pregnancy; 4) the role of Mycoplasma genitalium and trichomoniasis in urethritis/cervicitis and treatment-related implications; 5) lymphogranuloma venereum proctocolitis among men who have sex with men; 6) the criteria for spinal fluid examination to evaluate for neurosyphilis; 7) the emergence of azithromycin-resistant Treponema pallidum; 8) the increasing prevalence of antimicrobial-resistant Neisseria gonorrhoeae; 9) the sexual transmission of hepatitis C; 10) diagnostic evaluation after sexual assault; and 11) STD prevention approaches.

  6. The psychological aspects in sexually transmitted infections.

    Science.gov (United States)

    Campolmi, Eleonora; Santosuosso, Ugo; Silvestri, Caterina; Giomi, Barbara; Zuccati, Giuliano

    2016-04-01

    Over the last years the number of sexually transmitted diseases has greatly increased. This can be attributed mainly to less rigidity in the gender role and to the ever growing sexual liberalization. Sexuality today as in the past, represents an important and complex dimension of the human being. With respect to the psychological area many authors think that there are specific personality traits that to a higher extent compared to others might push individuals to carry out inconsiderate behavior among which there has been found a higher risk of sexually transmitted diseases (STD). In the present paper preliminary data of a research carried out provides information about sexual habits among patients of the IST of Florence. A sample of 344 individuals, from 15 to over 70-year-old, Italians and strangers, has been asked to fill up a self-administered questionnaire. Through these data the psychological aspects at the base of sexual habits in our reference sample are highlighted even more clearly. Through the analysis of these data it will be possible to get a larger number of information that can be used for the building of psychological support experiences that take into account the individual differences among patients one finds through consultations and support. The psychological support is very important for a lot of patients who belong to the center and show inappropriate sexual behavior and exposed to risky sexual behavior.

  7. [Risk of transfusional-transmitted infections].

    Science.gov (United States)

    Blejer, Jorgelina L; Carreras Vescio, Luis A; Salamone, Horacio J

    2002-01-01

    Although each donated unit of blood is tested for evidence of infection by specific agents, there are at least four potential reasons why transmission of these agents may still occur: a) the donor has negative laboratory test results during the early stages of infection, known as the window period, b) the existence of a chronic carrier state in which a clinically asymptomatic donor will persistently test negative on a screening assay, c) donors harbouring a mutant or atypical variant and d) laboratory errors when performing the screening tests. Measures to assure the safety of blood and blood components include use of voluntary donors, donor selection and questioning, laboratory testing for serological markers of infections, maintenance of registries of disqualified donors and, more recently, the introduction of direct testing for viral nucleic acids. All these measures must be accompanied by rigorous quality control systems. The potential risk of transfusion-transmitted infectious diseases can be estimated by reviewing the records of blood donations, the screening procedures and determining the prevalence of the serologic markers of infectious diseases. Accurate estimates of the risk of transfusion-transmitted infections are needed in order to monitor the safety of the blood supply and evaluate the yield and cost effectiveness of alternatives to allogeneic transfusion. Genomic screening for infectious agents, especially viruses, became possible with the development of various nucleic acid amplification techniques. They combine the advantages of direct detection of the organism with a sensitivity several orders of magnitude higher than that of traditional methods.

  8. Phase-only nulling for transmit antenna

    Science.gov (United States)

    Hussain, Moayyed A.; Yu, Kai-Bor

    1999-11-01

    This paper describes a technique for transmit antenna nulling for low-cost large sparse phased array radar system. Radar system described includes an array of elemental antennas, each with a transmit/receive (T/R) module. The T/R modules are operated at or near maximum output to achieve maximum CD-to-RF efficiency. A phase controller controls the phase shift, which are imparted by each module to its signal, to form a mainbeam and its associated sidelobes. A perturbation phase generator adds phase shifts computed, to form wide nulls in the sidelobe structure. The nulls are achieved at very minimal loss of gain, in the order of fraction of a dB. The speed of obtaining these nulls in real time allows a rapid steering of these nulls in a hostile environment. The thinned aperture allow designing a light weigh mobile system. In radar context, these nulls may be placed on a source of ground clutter, a set of jammers or a set of undesirable radio sources.

  9. Interference Alignment with Partially Coordinated Transmit Precoding

    CERN Document Server

    Yousafzai, Aimal Khan

    2011-01-01

    In this paper, we introduce an efficient interference alignment (IA) algorithm exploiting partially coordinated transmit precoding to improve the number of concurrent interference-free transmissions, i.e., the multiplexing gain, in multicell downlink. The proposed coordination model is such that each base-station simultaneously transmits to two users and each user is served by two base-stations. First, we show in a K-user system operating at the information theoretic upper bound of degrees of freedom (DOF), the generic IA is proper when $K \\leq 3$, whereas the proposed partially coordinated IA is proper when $K \\leq 5$. Then, we derive a non-iterative, i.e., one shot, IA algorithm for the proposed scheme when $K \\leq 5$. We show that for a given latency, the backhaul data rate requirement of the proposed method grows linearly with K. Monte-Carlo simulation results show that the proposed one-shot algorithm offers higher system throughput than the iterative IA at practical SNR levels.

  10. Multiple routes transmitted epidemics on multiplex networks

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Dawei [Information Security Center, State Key Laboratory of Networking and Switching Technology, Beijing University of Posts and Telecommunications, P.O. Box 145, Beijing 100876 (China); National Engineering Laboratory for Disaster Backup and Recovery, Beijing University of Posts and Telecommunications, Beijing 100876 (China); Shandong Provincial Key Laboratory of Computer Network, Shandong Computer Science Center, Jinan 250014 (China); Li, Lixiang [Information Security Center, State Key Laboratory of Networking and Switching Technology, Beijing University of Posts and Telecommunications, P.O. Box 145, Beijing 100876 (China); National Engineering Laboratory for Disaster Backup and Recovery, Beijing University of Posts and Telecommunications, Beijing 100876 (China); Peng, Haipeng, E-mail: penghaipeng@bupt.edu.cn [Information Security Center, State Key Laboratory of Networking and Switching Technology, Beijing University of Posts and Telecommunications, P.O. Box 145, Beijing 100876 (China); National Engineering Laboratory for Disaster Backup and Recovery, Beijing University of Posts and Telecommunications, Beijing 100876 (China); Luo, Qun; Yang, Yixian [Information Security Center, State Key Laboratory of Networking and Switching Technology, Beijing University of Posts and Telecommunications, P.O. Box 145, Beijing 100876 (China); National Engineering Laboratory for Disaster Backup and Recovery, Beijing University of Posts and Telecommunications, Beijing 100876 (China)

    2014-02-01

    This letter investigates the multiple routes transmitted epidemic process on multiplex networks. We propose detailed theoretical analysis that allows us to accurately calculate the epidemic threshold and outbreak size. It is found that the epidemic can spread across the multiplex network even if all the network layers are well below their respective epidemic thresholds. Strong positive degree–degree correlation of nodes in multiplex network could lead to a much lower epidemic threshold and a relatively smaller outbreak size. However, the average similarity of neighbors from different layers of nodes has no obvious effect on the epidemic threshold and outbreak size. -- Highlights: •We studies multiple routes transmitted epidemic process on multiplex networks. •SIR model and bond percolation theory are used to analyze the epidemic processes. •We derive equations to accurately calculate the epidemic threshold and outbreak size. •ASN has no effect on the epidemic threshold and outbreak size. •Strong positive DDC leads to a lower epidemic threshold and a smaller outbreak size.

  11. Prevention of soil-transmitted helminth infection

    Directory of Open Access Journals (Sweden)

    Luciene Mascarini-Serra

    2011-01-01

    Full Text Available Soil-transmitted helminths (STHs form one of the most important groups of infectious agents and are the cause of serious global health problems. The most important STHs are roundworms (Ascaris lumbricoides, whipworms (Trichuris trichiura and hookworms (Necator americanus or Ancylostoma duodenale; on a global level, more than a billion people have been infected by at least one species of this group of pathogens. This review explores the general concepts of transmission dynamics and the environment and intensity of infection and morbidity of STHs. The global strategy for the control of soil-transmitted helminthiasis is based on (i regular anthelminthic treatment, (ii health education, (iii sanitation and personal hygiene and (iv other means of prevention with vaccines and remote sensoring. The reasons for the development of a control strategy based on population intervention rather than on individual treatment are discussed, as well as the costs of the prevention of STHs, although these cannot always be calculated because interventions in health education are difficult to measure. An efficient sanitation infrastructure can reduce the morbidity of STHs and eliminates the underlying cause of most poverty-related diseases and thus supports the economic development of a country.

  12. Evaluation of extremely small horizontal emittance

    Directory of Open Access Journals (Sweden)

    T. Okugi

    1999-02-01

    Full Text Available The KEK Accelerator Test Facility (KEK-ATF was constructed to develop technologies for producing a low-emittance beam which will be required by future linear colliders. The KEK-ATF consists of an injector linac, a damping ring, and a beam extraction line. The basic optical structure of the damping ring is a FOBO lattice, which reduces the horizontal dispersion at the center of the bending magnets and, as a consequence, can produce an extremely small emittance beam. To verify the performance of such a unique, low-emittance lattice, it is crucial to measure the horizontal emittance. The horizontal emittance was measured using wire scanners in the beam extraction line. Since the horizontal beam position was not stable, we established a method to correct the measured beam size for position fluctuation (“jitter” and we succeeded in the observation of the so far smallest horizontal emittance in any accelerator. The measured horizontal emittance was 1.37±0.03nm at a beam energy of 1.285 GeV and a bunch population of \\(3–5\\×10^{9}, in agreement with the design value of 1.27–1.34 nm at the beam energy and the bunch population.

  13. The physical properties of the HH 30 jet from HST and ground-based data

    Science.gov (United States)

    Bacciotti, Francesca; Eislöffel, Jochen; Ray, Thomas P.

    1999-10-01

    We investigate the physical properties of the HH 30 jet by applying the spectroscopic diagnostic technique described in Bacciotti & Eislöffel (\\cite{be99}) to ground-based spectra and Hubble Space Telescope (HST) calibrated emission-line images. We derive the variation along the beam of the ionization fraction xe, of the total hydrogen density n_H and of the average excitation temperature Te, with a spatial sampling of 0.1" to 0.6" (depending on the dataset used) near the source of the flow and of 1.8" further out. In the jet xe rapidly rises from 0.065 at 0.2" to 0.1 at 0.4", and then slowly increases up to 0.140 within 2'' from the source. From 2.4" to 12.5", xe decreases very slowly down to a value of 0.04. The slow recombination in the outermost collimated part is consistent with a flow opening angle of about 2(deg) . At the beginning of the jet n_H is at least ~ 10(5) cm(-3) , but it decreases to 5 10(4) cm(-3) within the first arcsecond and then slowly falls to 10(4) cm(-3) at large distance from the source. On average Te decreases from ~ 2 10(4) K to 10(4) K within the first arcsecond of the jet, then it slowly decays to 6000-7000 K. In the faint counter-jet, which appears to be substantially more excited than the jet, xe rises from 0.07 up to 0.35 at 2-3 arcsec from the source, n_H decreases from about 8 10(4) cm(-3) to a few 10(3) cm(-3) , while Te is scattered around 1.2-1.3 10(4) K. A comparison between the observed and calculated line fluxes shows that the filling factor is of order unity in this flow. The emission-weighted jet width calculated with the parameters that we derive is in good agreement with the observed FWHM; we find, however, that the jet radius apparently goes to zero at the source location, defining an initial full opening angle of about 10(deg) . The intensity peaks, i.e. the knots, are clearly correlated with local temperature maxima. The ionization fraction and the electron and total densities do not show any evident increase at

  14. A Possible Origin of the H-H Objects in Young Stellar Outflows

    Science.gov (United States)

    de Gouveia dal Pino, E.; Opher, R.

    1990-11-01

    RESUMEN. La presencIa de flujos coljmados asocjados con objetos estelares j6venes es un fen6meno comun en reglones de formacI6n estelar. Estos chorros frecuentemente muestran una cadena de reglones de lineas de emjsI6n, a varIas de las cuales se les conoce desde bace mucho tlempo objetos HerbIg-Haro (HAl). En el presente trabajo examjnamos la poslbIlI dad de que estos nudos sean condensaciones producIdas por inestabilidad termica en un plasma que se se expande sujeto a `bremsstrahlung' reco - binaci6n y perdida por radjacj5n en lineas de emjsj6n. Nostramos que el valor minimo de = P0/PN0 bajo condjcjones Isobaricas para el crecimien to de la inestabilidad termica es = (6/5) [9/(STc\\)e) - 3/2]; en donde P0 es la presi6n de particulas, PM0 la presi6n magnetica, `)e la tasa de expansI5n y Tc el tiempo de enfriatniento radiativo en el flujo (3eI plasma ambiente. Haciendo calculos no lineales, encontratnos que l9s flujos colitnados de temperatura K, tasas de perdida de masa `4 = 10-6 - lO 8 Ne y velocidades de flujo VJ = 100-400 km/s, resultan favorables para la formacl6n de condensaciones por inestabilidad termica con contrastes de densidad Pp/ .3 -2.0 creados en intervalos de tiempo mas cortos que el tiempo estirnado de expansl6n en los chorros, en donde Pp(Po) es la densidad en la regi5n (ambiente) perturbada. ABSTRACT. The presence of collimated outflows associated with young stellar objects is a common phenomenon in star-fortning regions. These jets frequently show a chain of emission-line regions several of which have long been known as Herbig-Haro (H-H) objects. In this paper we examine the possibility that these knots are condensations produced by thermal instability in an expanding plasma , recombination and emission-line radiation losses. We show that the minimum value of = P /PNo under isobaric conditions for the growth of a thermal instability 0is = (6/5)1 [9/(STcN)e) - 3/2]; where P0 is the particle pressure, NQ tWe magnetic pressure, N) the expansion rate

  15. Dynamic study of a wind turbine blade with horizontal axis

    Energy Technology Data Exchange (ETDEWEB)

    Yousi, R.; El-Batanony, I.; Tritsch, J.B.; Naji, H.; Landjerit, B. [EUDIL, Dept. Mecanique, LML, CNRS URA 1441, 59 - Villeneuve d' Ascq (France)

    2001-04-01

    The study of the dynamic behavior of a wind turbine with horizontal axis can be undertaken by various methods of analysis. The effects of the change of the aerodynamic flow (in the steady and unsteady cases), the variation of parameters of the cinematic movement (angle of attack, pitch angle and yaw angle) and the definition of subsystems characteristics that makes the wind turbine (blade, nacelle and pylon) allow one to characterize the structural dynamic behavior of the wind turbine. It is therefore necessary to develop these items. Once this is done, the structural dynamic behavior of the system can be improved. The term 'improve' means the increase of the life duration by mastering the fatigue effects and the reduction of cost without sacrificing the aerodynamic output. The present study aims to examine the behavior of the blade, which is the main part of the wind turbine in that it that transmits forces to all other parts of the structure. The model is based on the theory of three-dimensional beams, under the assumption of variable sections of the type NACA 4415 airfoil, and takes into account membrane, transversal shear, flexion and free torsion effects. With regards to the aerodynamic loads (the lift, the drag and the pitching moment), a validation has been undertaken by considering experimental data and numerical results obtained by a CFD code (Fluent). The forces are obtained by means of a parametric CAD method interpolation of the aerodynamic poles by Bezier patch under geometrical constraints solved by a Simplex type algorithm. The emphasis is put on dynamic aspects by a complete processing of the dynamic equilibrium equation, applied to the wind turbine blade with horizontal axis. (authors)

  16. Adolescents' Sexually Transmitted Disease Protective Attitudes Predict Sexually Transmitted Disease Acquisition in Early Adulthood

    Science.gov (United States)

    Crosby, Richard A.; Danner, Fred

    2008-01-01

    Background: Estimates suggest that about 48% of nearly 19 million cases of sexually transmitted diseases (STDs) occurring annually in the United States are acquired by persons aged 15-24 years. The purpose of this study was to test the hypothesis that adolescents' attitudes about protecting themselves from STDs predict their laboratory-confirmed…

  17. Horizontal roof gap of backfill hydraulic support

    Institute of Scientific and Technical Information of China (English)

    张强; 张吉雄; 邰阳; 方坤; 殷伟

    2015-01-01

    For the backfill hydraulic support as the key equipment for achieving integration of backfilling and coal mining simultaneously in the practical process, its characteristics will directly influence the backfill body’s compression ratio. Horizontal roof gap, as a key parameter of backfilling characteristics, may impact the backfilling effect from the aspects of control of roof subsidence in advance, support stress, backfilling process and the support design. Firstly, the reason why horizontal roof gap exists was analyzed and its definition, causes and connotation were introduced, then adopting the Pro/E 3D simulation software, three typical 3D entity models of backfill hydraulic supports were built, based on the influence of horizontal roof gap on backfilling effect, and influence rules of four factors, i.e. support height, suspension height, suspension angle and tamping angle, were emphatically analyzed on horizontal roof gap. The results indicate that, the four factors all have significant impacts on horizontal roof gap, but show differences in influence trend and degree, showing negative linear correlation, positive linear correlation, positive semi-parabolic correlation and negative semi-parabolic correlation, respectively. Four legs type is the most adaptive to the four factors, while six legs (II) type has the poorest adaptability, and the horizontal roof gap is small under large support height, small suspension height, small suspension angle and large tamping angle situation. By means of optimizing structure components and their positional relation and suspension height of backfill scrape conveyor in the process of support design and through controlling working face deployment, roof subsidence in advance, mining height and backfilling during engineering application, the horizontal roof gap is optimized. The research results can be served as theoretical basis for support design and guidance for backfill support to have better performance in backfilling.

  18. Optical antenna gain. I - Transmitting antennas

    Science.gov (United States)

    Klein, B. J.; Degnan, J. J.

    1974-01-01

    The gain of centrally obscured optical transmitting antennas is analyzed in detail. The calculations, resulting in near- and far-field antenna gain patterns, assume a circular antenna illuminated by a laser operating in the TEM-00 mode. A simple polynomial equation is derived for matching the incident source distribution to a general antenna configuration for maximum on-axis gain. An interpretation of the resultant gain curves allows a number of auxiliary design curves to be drawn that display the losses in antenna gain due to pointing errors and the cone angle of the beam in the far field as a function of antenna aperture size and its central obscuration. The results are presented in a series of graphs that allow the rapid and accurate evaluation of the antenna gain which may then be substituted into the conventional range equation.

  19. Optical antenna gain. 1: transmitting antennas.

    Science.gov (United States)

    Klein, B J; Degnan, J J

    1974-09-01

    The gain of centrally obscured optical transmitting antennas is analyzed in detail. The calculations, resulting in near- and far-field antenna gain patterns, assume a circular antenna illuminated by a laser operating in the TEM(00) mode. A simple polynomial equation is derived for matching the incident source distribution to a general antenna configuration for maximum on-axis gain. An interpretation of the resultant gain curves allows a number of auxiliary design curves to be drawn that display the losses in antenna gain due to pointing errors and the cone angle of the beam in the far field as a function of antenna aperture size and its central obscuration. The results are presented in a series of graphs that allow the rapid and accurate evaluation of the antenna gain which may then be substituted into the conventional range equation.

  20. Sexually Transmitted Disease and Male Infertility

    DEFF Research Database (Denmark)

    Fode, Mikkel; Fusco, Ferdinando; Lipshultz, Larry

    2016-01-01

    CONTEXT: Theoretically, sexually transmitted diseases (STDs) have the potential to disrupt male fertility; however, the topic remains controversial. OBJECTIVE: To describe the possible association between STDs and male infertility and to explore possible pathophysiologic mechanisms. EVIDENCE...... ACQUISITION: We performed a systematic literature review in accordance with the PRISMA guidelines. PubMed, Embase, and the Cochrane Library were searched for articles published before January 1, 2016, using the MeSH terms for a variety of STDs and infertility. The search was restricted to human studies...... performed in men and published in English. Studies were included if they contained original data on a possible association or a cause-and-effect relationship between STD and male infertility. Studies were considered only if they included an appropriate control group and/or comprehensive laboratory data. Due...

  1. Sexually Transmitted Diseases on Bipartite Graph

    Science.gov (United States)

    Wen, Luo-Sheng; Zhong, Jiang; Yang, Xiao-Fan

    2009-01-01

    We study the susceptible-infected-susceptible (SIS) epidemic model on bipartite graph. According to the difference of sex conception in western and oriental nations, we construct the Barabási Albert-Barabási Albert (BA-BA) model and Barabási-Albert Homogeneity (BA-HO) model for sexually transmitted diseases (STDs). Applying the rate equation approach, the positive equilibria of both models are given analytically. We find that the ratio between infected females and infected males is distinctly different in both models and the infected density in the BA-HO model is much less than that in the BA-BA model. These results explain that the countries with small ratio have less infected density than those with large ratio. Our numerical simulations verify these theoretical results.

  2. Sexually Transmitted Diseases on Bipartite Graph

    Institute of Scientific and Technical Information of China (English)

    WEN Luo-Sheng; ZHONG Jiang; YANG Xiao-Fan

    2009-01-01

    We study the susceptible-infected-susceptible (SIS) epidemic model on bipartite graph. According to the dif-ference of sex conception in western and oriental nations, we construct the Barabasi Albert-Barabasi Albert (BA-BA) model and Barabasi-Albert Homogeneity (BA-HO) model for sexually transmitted diseases (STDs). Applying the rate equation approach, the positive equilibria of both models are given analytically. We lind that the ratio between infected females and infected males is distinctly different in both models and the infected den-sity in the BA-HO model is much less than that in the BA-BA model. These results explain that the countries with small ratio have less infected density than those with large ratio. Our numerical simulations verify these theoretical results.

  3. Interviews with candidates for president transmitted

    Directory of Open Access Journals (Sweden)

    Wilson Gomes

    2012-07-01

    Full Text Available In election years, television interviews with presidential candidates, broadcast live, i.e. without the use of editing, have become an important genre of journalistic representation in Brazilian political campaigns. These interviews are conducted in network studios by well-known Brazilian news anchors. The fact that these interviews are transmitted directly to the electorate in an unedited form is generally offered as a guarantee of a genuine, authentic portrayal of the candidates themselves. The present work proposes that live network candidate interviews, rather than a means of political presentation on television, are actually an arena in which the institution of journalism attempts to use rhetorical and argumentative means to control the candidates’ discourse without relying on the traditional advantages conferred in daily news coverage.

  4. A positive feedback synapse from retinal horizontal cells to cone photoreceptors.

    Directory of Open Access Journals (Sweden)

    Skyler L Jackman

    2011-05-01

    Full Text Available Cone photoreceptors and horizontal cells (HCs have a reciprocal synapse that underlies lateral inhibition and establishes the antagonistic center-surround organization of the visual system. Cones transmit to HCs through an excitatory synapse and HCs feed back to cones through an inhibitory synapse. Here we report that HCs also transmit to cone terminals a positive feedback signal that elevates intracellular Ca(2+ and accelerates neurotransmitter release. Positive and negative feedback are both initiated by AMPA receptors on HCs, but positive feedback appears to be mediated by a change in HC Ca(2+, whereas negative feedback is mediated by a change in HC membrane potential. Local uncaging of AMPA receptor agonists suggests that positive feedback is spatially constrained to active HC-cone synapses, whereas the negative feedback signal spreads through HCs to affect release from surrounding cones. By locally offsetting the effects of negative feedback, positive feedback may amplify photoreceptor synaptic release without sacrificing HC-mediated contrast enhancement.

  5. Similar sponge-associated bacteria can be acquired via both vertical and horizontal transmission

    DEFF Research Database (Denmark)

    Sipkema, Detmer; de Caralt, Sònia; Morillo, Jose A

    2015-01-01

    Marine sponges host diverse communities of microorganisms that are often vertically transmitted from mother to oocyte or embryo. Horizontal transmission has often been proposed to co-occur in marine sponges, but the mechanism is poorly understood. To assess the impact of the mode of transmission...... on the microbial assemblages of sponges, we analysed the microbiota in sympatric sponges that have previously been reported to acquire bacteria via either vertical (Corticium candelabrum and Crambe crambe) or horizontal transmission (Petrosia ficiformis). The comparative study was performed by PCR......-DGGE and pyrosequencing of barcoded PCR-amplified 16S rRNA gene fragments. We found that P. ficiformis and C. candelabrum each harbor their own species-specific bacteria, but they are similar to other high-microbial-abundance sponges, while the low-microbial-abundance sponge C. crambe hosts microbiota of a very different...

  6. Horizontal alveolar bone loss: A periodontal orphan

    Directory of Open Access Journals (Sweden)

    Jayakumar A

    2010-01-01

    Full Text Available Background: Attempts to successfully regenerate lost alveolar bone have always been a clinician′s dream. Angular defects, at least, have a fairer chance, but the same cannot be said about horizontal bone loss. The purpose of the present study was to evaluate the prevalence of horizontal alveolar bone loss and vertical bone defects in periodontal patients; and later, to correlate it with the treatment modalities available in the literature for horizontal and vertical bone defects. Materials and Methods: The study was conducted in two parts. Part I was the radiographic evaluation of 150 orthopantomographs (OPGs (of patients diagnosed with chronic periodontitis and seeking periodontal care, which were digitized and read using the AutoCAD 2006 software. All the periodontitis-affected teeth were categorized as teeth with vertical defects (if the defect angle was ≤45° and defect depth was ≥3 mm or as having horizontal bone loss. Part II of the study comprised search of the literature on treatment modalities for horizontal and vertical bone loss in four selected periodontal journals. Results: Out of the 150 OPGs studied, 54 (36% OPGs showed one or more vertical defects. Totally, 3,371 teeth were studied, out of which horizontal bone loss was found in 3,107 (92.2% teeth, and vertical defects were found only in 264 (7.8% of the teeth, which was statistically significant (P<.001. Search of the selected journals revealed 477 papers have addressed the treatment modalities for vertical and horizontal types of bone loss specifically. Out of the 477 papers, 461 (96.3% have addressed vertical bone loss, and 18 (3.7% have addressed treatment options for horizontal bone loss. Two papers have addressed both types of bone loss and are included in both categories. Conclusion: Horizontal bone loss is more prevalent than vertical bone loss but has been sidelined by researchers as very few papers have been published on the subject of regenerative treatment

  7. The HhH2/NDD domain of the Drosophila Nod chromokinesin-like protein is required for binding to chromosomes in the oocyte nucleus.

    Science.gov (United States)

    Cui, Wei; Hawley, R Scott

    2005-12-01

    Nod is a chromokinesin-like protein that plays a critical role in segregating achiasmate chromosomes during female meiosis. The C-terminal half of the Nod protein contains two putative DNA-binding domains. The first of these domains, known as the HMGN domain, consists of three tandemly repeated high-mobility group N motifs. This domain was previously shown to be both necessary and sufficient for binding of the C-terminal half of Nod to mitotic chromosomes in embryos. The second putative DNA-binding domain, denoted HhH(2)/NDD, is a helix-hairpin-helix(2)/Nod-like DNA-binding domain. Although the HhH(2)/NDD domain is not required or sufficient for chromosome binding in embryos, several well-characterized nod mutations have been mapped in this domain. To characterize the role of the HhH(2)/NDD domain in mediating Nod function, we created a series of UAS-driven transgene constructs capable of expressing either a wild-type Nod-GFP fusion protein or proteins in which the HhH(2)/NDD domain had been altered by site-directed mutagenesis. Although wild-type Nod-GFP localizes to the oocyte chromosomes and rescues the segregation defect in nod mutant oocytes, two of three proteins carrying mutants in the HhH(2)/NDD domain fail to either rescue the nod mutant phenotype or bind to oocyte chromosomes. However, these mutant proteins do bind to the polytene chromosomes in nurse-cell nuclei and enter the oocyte nucleus. Thus, even though the HhH(2)/NDD domain is not essential for chromosome binding in other cell types, it is required for chromosome binding in the oocyte. These HhH(2)/NDD mutants also block the localization of Nod to the posterior pole of stage 9-10A oocytes, a process that is thought to facilitate the interaction of Nod with the plus ends of microtubules (Cui et al. 2005). This observation suggests that the Nod HhH2/NDD domain may play other roles in addition to binding Nod to meiotic chromosomes.

  8. Medium Screening and Optimization for Soy Bean Rhizobium (Rhizobium fredii) HH103%大豆根瘤菌HH103菌株培养基的筛选与优化

    Institute of Scientific and Technical Information of China (English)

    肖亦农; 徐琼

    2011-01-01

    Quick-growing soy bean rhizobium (Rhizobium fredii) HH103 was used as a tested strain, and adopted single factor nitrogen source utilization experiment and orthogonal design experiment to confirm the optimum medium and its formula. The results showed that the strain grew well on YMA, the optimum carbon source was sucrose, and the optimum nitrogen was yeast extract with the optimum medium formula as follows (in g/L) : sucrose 11, yeast extract 0.9, K2HPO40.5, MnSO4 0.005, CaCl2 0.1, KH2PO40.5, MgSO40.2, KNO30.77, (NH4)2HPO4 0. 33, FeCl3 0.005, andpH7.2.%以快生型大豆根瘤菌HH103菌株为供试菌株,采用单因素碳氮源利用试验和正交设计试验,确定最佳培养基及其配方.结果表明:该菌株在YMA中生长良好,最佳碳源为蔗糖,最佳氮源为酵母膏,最佳培养基成分配方(g/L):蔗糖11,酵母膏0.9,K2HPO4 0.5,MnSO40.005,CaCl2 0.1,KH2PO4 0.5,MgSO4 0.2,KNO30.77,(NH4)2HPO4 0.33,FeCl3 0.005,pH 7.2.

  9. MULTIPLE TRELLIS CODED ORTHOGONAL TRANSMIT SCHEME FOR MULTIPLE ANTENNA SYSTEMS

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    In this paper, a novel multiple trellis coded orthogonal transmit scheme is proposed to exploit transmit diversity in fading channels. In this scheme, a unique vector from a set of orthogonal vectors is assigned to each transmit antenna. Each of the output symbols from the multiple trellis encoder is multiplied with one of these orthogonal vectors and transmitted from corresponding transmit antennas. By correlating with corresponding orthogonal vectors, the receiver separates symbols transmitted from different transmit antennas.This scheme can be adopted in coherent/differential systems with any number of transmit antennas. It is shown that the proposed scheme encompasses the conventional trellis coded unitary space-time modulation based on the optimal cyclic group codes as a special case. We also propose two better designs over the conventional trellis coded unitary space-time modulation. The first design uses 8 Phase Shift Keying (8-PSK) constellations instead of 16 Phase Shift Keying (16-PSK) constellations in the conventional trellis coded unitary space-time modulation. As a result, the product distance of this new design is much larger than that of the conventional trellis coded unitary space-time modulation. The second design introduces constellations with multiple levels of amplitudes into the design of the multiple trellis coded orthogonal transmit scheme. For both designs, simulations show that multiple trellis coded orthogonal transmit schemes can achieve better performance than the conventional trellis coded unitary space-time schemes.

  10. Diffuser Augmented Horizontal Axis Tidal Current Turbines

    Directory of Open Access Journals (Sweden)

    Nasir Mehmood

    2012-09-01

    Full Text Available The renewal energy technologies are increasingly popular to ensure future energy sustenance and address environmental issues. The tides are enormous and consistent untapped resource of renewable energy. The growing interest in exploring tidal energy has compelling reasons such as security and diversity of supply, intermittent but predictable and limited social and environmental impacts. The tidal energy industry is undergoing an increasing shift towards diffuser augmented turbines. The reason is the higher power output of diffuser augmented turbines compared to conventional open turbines. The purpose of this study is to present a comprehensive review of diffuser augmented horizontal axis tidal current turbines. The components, relative advantages, limitations and design parameters of diffuser augmented horizontal axis tidal current turbines are presented in detail. CFD simulation of NACA 0016 airfoil is carried out to explore its potential for designing a diffuser. The core issues associated with diffuser augmented horizontal axis tidal current turbines are also discussed.

  11. HORIZONTAL WELL DRILL-IN FLUIDS

    Directory of Open Access Journals (Sweden)

    Nediljka Gaurina-Međimurec

    1998-12-01

    Full Text Available Main objective of horizontal driling is to place a drain-hole for a long distance within the pay zone to enhance productivity or injectivity. In drilling horizontal wells, more serious problems appear than in drilling vertical wells. These problems are: poor hole cleaning, excessive torque and drag, hole filling, pipe stucking, wellbore instability, loss of circulation, formation damage, poor cement job, and difficulties at logging jobs. From that reason, successful drilling and production of horizontal well depends largely on the fluid used during drilling and completion phases. Several new fluids, that fulfill some or all of required properties (hole cleaning, cutting suspension, good lubrication, and relative low formation damage, are presented in this paper.

  12. Horizontal stirring in the global ocean

    CERN Document Server

    Hernández-Carrasco, I; Hernández-García, E; Turiel, A

    2011-01-01

    Horizontal mixing and the distribution of coherent structures in the global ocean are analyzed using Finite-Size Lyapunov Exponents (FSLE), computed for the surface velocity field derived from the Ocean general circulation model For the Earth Simulator (OFES). FSLEs measure horizontal stirring and dispersion; additionally, the transport barriers which organize the oceanic flow can roughly be identified with the ridges of the FSLE field. We have performed a detailed statistical study, particularizing for the behaviour of the two hemispheres and different ocean basins. The computed Probability Distributions Functions (PDFs) of FSLE are broad and asymmetric. Horizontal mixing is generally more active in the northern hemisphere than in the southern one. Nevertheless the Southern Ocean is the most active ocean, and the Pacific the less active one. A striking result is that the main currents can be classified in two 'activity classes': Western Boundary Currents, which have broad PDFs with large FSLE values, and Eas...

  13. Analysis of an Underground Horizontal Electrically Small Antenna

    Directory of Open Access Journals (Sweden)

    Shuwei Dong

    2015-01-01

    Full Text Available This work is about a horizontal electrically small wire antenna located underground, which transmits electromagnetic signals to the ground. To solve this problem, the expressions of the magnetic vector potential and the electric field are derived. Further, a quasi-static situation is considered in the condition of extremely low frequency (ELF or super low frequency (SLF to make an approximation on Sommerfeld integral for easy calculation. The method of moments (MOM is used to solve the current distribution along the antenna surface at different frequencies, which lays a good foundation for obtaining the electric field of the antenna. Then the three components of the electric field along the radial distance at different polar angles on the ground are investigated, as well as the voltage received on the ground. Furthermore, some influence factors of the antenna are analyzed in order to know the operating characteristics of the antenna better. The results indicate that the antenna length and relative permittivity have a positive correlation with the radial component of the electric field magnitude, while the buried depth, frequency, and conductivity have a negative correlation with that. The influence of these factors on electric field is obvious except the relative permittivity.

  14. Horizontal Transmission of Cytosolic Sup35 Prions by Extracellular Vesicles

    Directory of Open Access Journals (Sweden)

    Shu Liu

    2016-07-01

    Full Text Available Prions are infectious protein particles that replicate by templating their aggregated state onto soluble protein of the same type. Originally identified as the causative agent of transmissible spongiform encephalopathies, prions in yeast (Saccharomyces cerevisiae are epigenetic elements of inheritance that induce phenotypic changes of their host cells. The prototype yeast prion is the translation termination factor Sup35. Prions composed of Sup35 or its modular prion domain NM are heritable and are transmitted vertically to progeny or horizontally during mating. Interestingly, in mammalian cells, protein aggregates derived from yeast Sup35 NM behave as true infectious entities that employ dissemination strategies similar to those of mammalian prions. While transmission is most efficient when cells are in direct contact, we demonstrate here that cytosolic Sup35 NM prions are also released into the extracellular space in association with nanometer-sized membrane vesicles. Importantly, extracellular vesicles are biologically active and are taken up by recipient cells, where they induce self-sustained Sup35 NM protein aggregation. Thus, in mammalian cells, extracellular vesicles can serve as dissemination vehicles for protein-based epigenetic information transfer.

  15. El horizonte estético

    OpenAIRE

    Perniola, Mario

    2004-01-01

    La existencia de un horizonte estético depende de la coexistencia de múltiples factores de distinta naturaleza que interactúan entre ellos. No bastan las reflexiones en torno a lo bello y al arte para crear un horizonte estético. La palabra “estética” es introducida en el Settecento por la filosofía para indicar una articulación disciplinar propia que pudiera ubicarse cerca de la lógica; esta circunstancia histórica, sin embargo, no debe hacernos olvidar que la filosofía es desde su nacimient...

  16. Fourth international seminar on horizontal steam generators

    Energy Technology Data Exchange (ETDEWEB)

    Tuomisto, H. [ed.] [IVO Group, Vantaa (Finland); Purhonen, H. [ed.] [VTT, Espoo (Finland); Kouhia, V. [ed.] [Lappeenranta Univ. of Technology (Finland)

    1997-12-31

    The general objective of the International Seminars of Horizontal Steam Generator Modelling has been the improvement in understanding of realistic thermal hydraulic behaviour of the generators when performing safety analyses for VVER reactors. The main topics presented in the fourth seminar were: thermal hydraulic experiments and analyses, primary collector integrity, feedwater distributor replacement, management of primary-to-secondary leakage accidents and new developments in the VVER safety technology. The number of participants, representing designers and manufacturers of the horizontal steam generators, plant operators, engineering companies, research organizations, universities and regulatory authorities, was 70 from 10 countries.

  17. Horizontal Roll Vortices and Crown Fires.

    Science.gov (United States)

    Haines, Donald A.

    1982-06-01

    Observational evidence from nine crown fires suggests that horizontal roll vortices are a major mechanism in crown-fire spread. Post-burn aerial photography indicates that unburned tree-crown streets are common with crown fire. Investigation of the understory of these crown streets after two fires showed uncharred tree trunks along a center line. This evidence supports a hypothesis of vortex action causing strong downward motion of air along the streets. Additionally, photographs of two ongoing crown fires show apparent horizontal roll vortices. Discussion also includes laboratory and numerical studies in fluid dynamics that may apply to crown fires.

  18. Horizontal transmission of nervous necrosis virus between turbot Scophthalmus maximus and Atlantic cod Gadus morhua using cohabitation challenge.

    Science.gov (United States)

    Korsnes, Kjetil; Karlsbakk, Egil; Nylund, Are; Nerland, Audun Helge

    2012-05-15

    Experimental horizontal transmission of nervous necrosis virus (NNV) originating from halibut Hippoglossus hippoglossus was studied through cohabitation of intraperitoneally (i.p.) injected fish with uninfected fish for 125 d. The experimental groups consisted of i.p. injected turbot Scophthalmus maximus or i.p. injected Atlantic salmon Salmo salar with turbot, salmon or Atlantic cod Gadus morhua cohabitants. The initial weights were cod 10 g, salmon 40 g and turbot 3 g. NNV was detected in brain, eye and spleen by real-time reverse transcriptase PCR (qRT-PCR) in cod cohabitated with i.p. injected turbot after 90 and 125 d, suggesting NNV infection was transmitted horizontally from the turbot to cod. NNV was not detected in salmon that were cohabitated with i.p. challenged turbot or salmon. This study shows that NNV strains belonging to the Barfin Flounder Nervous Necrosis Virus (BFNNV) clade may be transmitted from halibut to cod via water. Hence there is a potential risk of horizontal transmission of the virus from farmed halibut to farmed and wild cod. The lack of detection of NNV in cohabitant salmon suggests that this fish species is less susceptible than cod, or not susceptible, to horizontal NNV transmission. This result might be influenced by the size of salmon, viral load in i.p. injected cohabitants or insufficient duration of the experiment.

  19. Transmit Power Optimisation in Wireless Network

    Directory of Open Access Journals (Sweden)

    Besnik Terziu

    2011-09-01

    Full Text Available Transmit power optimisation in wireless networks based on beamforming have emerged as a promising technique to enhance the spectrum efficiency of present and future wireless communication systems. The aim of this study is to minimise the access point power consumption in cellular networks while maintaining a targeted quality of service (QoS for the mobile terminals. In this study, the targeted quality of service is delivered to a mobile station by providing a desired level of Signal to Interference and Noise Ratio (SINR. Base-stations are coordinated across multiple cells in a multi-antenna beamforming system. This study focuses on a multi-cell multi-antenna downlink scenario where each mobile user is equipped with a single antenna, but where multiple mobile users may be active simultaneously in each cell and are separated via spatial multiplexing using beamforming. The design criteria is to minimize the total weighted transmitted power across the base-stations subject to SINR constraints at the mobile users. The main contribution of this study is to define an iterative algorithm that is capable of finding the joint optimal beamformers for all basestations, based on a correlation-based channel model, the full-correlation model. Among all correlated channel models, the correlated channel model used in this study is the most accurate, giving the best performance in terms of power consumption. The environment here in this study is chosen to be Non-Light of- Sight (NLOS condition, where a signal from a wireless transmitter passes several obstructions before arriving at a wireless receiver. Moreover there are many scatterers local to the mobile, and multiple reflections can occur among them before energy arrives at the mobile. The proposed algorithm is based on uplink-downlink duality using the Lagrangian duality theory. Time-Division Duplex (TDD is chosen as the platform for this study since it has been adopted to the latest technologies in Fourth

  20. An investigation into crystalline phases and nano structural and mechanical properties of HH heat resistant stainless steels

    Directory of Open Access Journals (Sweden)

    M Hosseini

    2015-12-01

    Full Text Available In the present work, the effects of different casting parameters including pouring temperature and cooling rate on stainless steel structures and mechanical properties of heat resistant alloy (HH were studied. Mo nanoparticles were synthesized through sol-gel method and were coated on the stainless steel device using spin-coating method. The effect of coating layer on the device was studied by using XRD (X-Ray Diffraction and FT-IR (Fourier Transform Infra red and SEM (Scanning Electron Microscopy techniques. The obtained results indicated an enhancement of corrosion, surface abrasion protection without changing metal surface structure, and a reduction of leakage current through the stainless steel device. Furthermore, pouring temperature and cooling rate increase caused a fine grain structure to be acquired with less carbides and better distribution in the austenitic matrix.

  1. Phased Array Transmit Antenna for a Satellite

    Science.gov (United States)

    Huggins, R. W.; Heisen, P. T.; Miller, G. E.; McMeen, D. J.; Perko, K. L.

    1999-01-01

    Active phased array antennas with electronically scanned beams offer advantages over high gain parabolic dish antennas currently used on spacecraft. Benefits include the elimination of deployable structures, no moving parts, and no torque disturbances that moving antennas impart to the spacecraft. The latter results in the conservation of spacecraft power, and the ability to take precision optical data while transmitting data. Such an antenna has been built under a contract from NASA Goddard Space Flight Center for the New Millennium Program EO- 1 satellite where it will act as the primary highspeed scientific data communication link. The antenna operates at X-band, has an integral controller and power conditioner, communicates with the spacecraft over a 1773 optical data bus, and is space qualified for low earth orbit (705 Km altitude). The nominal mission length is one year, and the operational requirement is for one 10 minute transmission a day over Spitsbergen, Norway. Details of the antenna and its performance will be described in the following paper.

  2. Sexually transmitted diseases in children in India

    Directory of Open Access Journals (Sweden)

    Dhawan Jyoti

    2010-01-01

    Full Text Available Sexually transmitted diseases (STDs in children are not uncommon in India, though systematic epidemiological studies to determine the exact prevalence are not available. STDs in children can be acquired via sexual route or, uncommonly, via non-sexual route such as accidental inoculation by a diseased individual. Neonatal infections are almost always acquired intrauterine or during delivery. Voluntary indulgence in sexual activity is also an important factor in acquisition of STDs in childhood. Sexual abuse and sex trafficking remain the important problems in India. Surveys indicate that nearly half of the children are sexually abused. Most at risk children are street-based, homeless or those living in or near brothels. Last two decades have shown an increase in the prevalence of STDs in children, though most of the data is from northern part of the country and from major hospitals. However, due to better availability of antenatal care to majority of women, cases of congenital syphilis have declined consistently over the past two-three decades. Other bacterial STDs are also on decline. On the other hand, viral STDs such as genital herpes and anogenital warts are increasing. This reflects trends of STDs in the adult population. Concomitant HIV infection is uncommon in children. Comprehensive sex education, stringent laws to prevent sex trafficking and child sexual abuse, and antenatal screening of all the women can reduce the prevalence of STDs in children.

  3. Molecular Diagnostics for Soil-Transmitted Helminths

    Science.gov (United States)

    O'Connell, Elise M.; Nutman, Thomas B.

    2016-01-01

    Historically, the diagnosis of soil-transmitted helminths (STHs) (e.g., Strongyloides stercoralis, Trichuris trichiura, Ancylostoma duodenale, Necator americanus, and Ascaris lumbricoides) has relied on often-insensitive microscopy techniques. Over the past several years, there has been an effort to use molecular diagnostics, particularly quantitative polymerase chain reaction (qPCR), to detect intestinal pathogens. While some platforms have been approved by regulatory bodies (e.g., Food and Drug Administration) to detect intestinal bacteria, viruses, and protozoa, there are no approved tests currently available for STH. Although studies comparing qPCR to microscopy methods for STH are imperfect, due in large part to a lack of a sufficient gold standard, they do show a significant increase in sensitivity and specificity of qPCR compared with microscopic techniques. These studies, as well as the advantages and disadvantages of using qPCR for STH diagnosis, are discussed. Guidelines for those designing future studies utilizing qPCR are proposed for optimizing results, as is the proposition for using standardized molecular diagnostics routinely for STH in clinical laboratories and for field-based studies when possible. PMID:27481053

  4. Sexually transmitted infections and older adults.

    Science.gov (United States)

    Johnson, Beverly K

    2013-11-01

    Older adults continue to be sexually active in their later years. A range of sexually transmitted infections (STIs) such as chlamydia, gonorrhea, syphilis, and HIV have been reported among older adults. Risk factors for STIs in older populations include (a) normal sexual changes associated with aging (e.g., increased time to attain an erection, decreased vaginal lubrication, decreases in sexual hormones); (b) psychosocial changes (e.g., loss of partner or spouse and re-entering the dating scene); and (c) risky sexual behaviors, including no or infrequent use of condoms. Screening of adults for STIs should occur regardless of age based on guidelines such as those from the Centers for Disease Control and Prevention and the U.S. Preventive Services Task Force. As discussed in this article, nurses can use assessment guides and engage in interventions such as counseling and education with older adults to reduce STI risk or refer for treatment. Numerous online resources exist for both nurses and older adults to increase knowledge of STIs.

  5. Depression Among Sexually Transmitted Disease Patients

    Institute of Scientific and Technical Information of China (English)

    黄长征; 李碧芳; 涂亚庭; 刘志香; 林能兴

    2001-01-01

    Objective: To investigate the depression status of patients with sexually transmitted diseases (STDs).Methods: The depression status of fifty-one hospitalized STD patients was evaluated in a randomized control study using Zung's Quantitative Table. 18 healthy control patients with similar demographic backgrounds were randomly chosen as controls. Patients with scores above or equal to 40 were considered to be suffering from depression.Results: The prevalence rate of depression in the patient group was obviously higher than that of in the control (X2=16.456,P<0.01). Prevalence of depression was found to be significantly related to occupation (P<0.05). Though the prevalence was not found to differ significantly between those with a treatment course less than 2 months and those with one longer or equal to 2 months (X2=0.041, P>0.05), the mean depression scores of the former group were significantly higher than those of the latter (P<0.01). No significant differences were found between new versus relapsing disease, married versus non-married, male versus female, or differing educational backgrounds.Conclusion: STD patients showed significant prevalence of depression.

  6. A Case Study of Horizontal Teacher Evaluation.

    Science.gov (United States)

    Johnson, Trav D.

    Horizontal teacher evaluation increases understanding of teaching through the critical examination of educational goals and classroom practices. This examination includes teachers' classroom observations of one another coupled with in-depth teacher conversations or dialogue about teaching aims and practices. A qualitative case study of a…

  7. Third international seminar on horizontal steam generators

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    The Third International Seminar on Horizontal Steam Generators held on October 18-20, 1994 in Lappeenranta, consisted of six sessions dealing with the topics: thermal hydraulic experiments and analyses, primary collector integrity, management of primary-to-secondary leakage accidents, feedwater collector replacement and discussion of VVER-440 steam generator safety issues.

  8. Parametric study for horizontal steam generator modelling

    Energy Technology Data Exchange (ETDEWEB)

    Ovtcharova, I. [Energoproekt, Sofia (Bulgaria)

    1995-12-31

    In the presentation some of the calculated results of horizontal steam generator PGV - 440 modelling with RELAP5/Mod3 are described. Two nodalization schemes have been used with different components in the steam dome. A study of parameters variation on the steam generator work and calculated results is made in cases with separator and branch.

  9. Evaluation of horizontal magnification on panoramic images

    Directory of Open Access Journals (Sweden)

    Maryam Raoof

    2013-01-01

    Full Text Available Aims: This study evaluated the horizontal magnification of images taken from adults and pediatrics with PM 2002 CC Planmeca analogue machine. Materials and Methods: A series of 120 panoramic radiographs were obtained of 60 adults and 60 pediatrics. For all patients, negative impressions were used to make positive casts of the teeth. A caliper was used to measure the maximum mesiodistal length of the buccal surface of all teeth except canines on both casts and radiographs. The horizontal magnification factor was calculated for incisor, premolar, and molar regions by dividing the values obtained from the casts by the values obtained from the radiographs. Statistical Analysis: Independent t-test and one-way analysis of variance (ANOVA were used. Results: The results indicated that with regard to adults, maxillary and mandibular incisor regions, unlike the other two sessions, didn′t show significant difference of the mean magnification of horizontal dimension (P = 0.5. In pediatrics, the comparison between mean magnification factors of all subgroups showed significant difference (P < 0.0001. Despite the adults′ radiographs, the results of pediatrics′ radiographs showed significantly higher magnification than the index listed by the manufacturer of the radiographic machine used. Conclusion: The present study results point to the fact that PM 2002 CC Proline panoramic machine makes possible precise measurements on radiographs of adults′ jaws in the horizontal dimension.

  10. Fermion mass hierarchy and global horizontal symmetries

    Energy Technology Data Exchange (ETDEWEB)

    Gelmini, G.B.; Gerard, J.M.; Yanagida, T.; Zoupanos, G. (European Organization for Nuclear Research, Geneva (Switzerland))

    1984-02-02

    We present a mechanism for quark mass generation in zeroth order using induced representations rather than the minimization of the horizontal potential. Using a simplicity criterion, we derive a realistic mass matrix. We also discuss a possible application of the mechanism to various models.

  11. Horizontal gene transfer in the phytosphere

    NARCIS (Netherlands)

    Elsas, van J.D.; Turner, S.; Bailey, M.J.

    2003-01-01

    Here, the ecological aspects of gene transfer processes between bacteria in the phytosphere are examined in the context of emerging evidence for the dominant role that horizontal gene transfer (HGT) has played in the evolutionary shaping of bacterial communities. Moreover, the impact of the putative

  12. Flow mapping for ESS horizontal target

    Energy Technology Data Exchange (ETDEWEB)

    Takeda, Y.; Kikura, H.; Taishi, T. [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

    1997-09-01

    Flow behaviour for ESS horizontal target is studied experimentally using two dimensional water model. A velocity field of stationary flow in reaction zone has been obtained. Three dimensional effect was also studied as a spanwise flow structure. (author) 3 figs., 3 refs.

  13. Buoyancy Driven Natural Ventilation through Horizontal Openings

    DEFF Research Database (Denmark)

    Heiselberg, Per

    2009-01-01

    An experimental study of the phenomenon of buoyancy driven natural ventilation through single-sided horizontal openings was performed in a full-scale laboratory test rig. The measurements were made for opening ratios L/D ranging from 0.027 to 4.455, where L and D are the length of the opening...

  14. Teaching Activities on Horizontal Nuclear Proliferation.

    Science.gov (United States)

    Zola, John

    1990-01-01

    Provides learning activities concerning the horizontal proliferation of nuclear weapons. Includes step-by-step directions for four activities: (1) the life cycle of nuclear weapons; (2) nuclear nonproliferation: pros and cons; (3) the nuclear power/nuclear weapons connection; and (4) managing nuclear proliferation. (NL)

  15. Mud and cement for horizontal wells

    Energy Technology Data Exchange (ETDEWEB)

    Zurdo, C.; Georges, C.; Martin, M.

    1986-01-01

    High-angle and horizontal well bores raise many questions concerning the characteristics of mud and cement. This paper is a summary of the authors' knowledge and work on these two subjects. For all research carried out, large or full-scale laboratory test plants were used. Cutting transport is not only a problem in horizontal conditions but hole angles of 25 to 65/sup 0/ can be even more critical when parameters such as mud rheological properties and velocities are not optimized. Drilling a long horizontal drain creates a dynamic annulus pressure unbalance. This can lead to a loss and kick situation. Two test benches were thus used to obtain a good understanding of the inefficiency of conventional plugging methods and of the difficulties of gas migration control in subhorizontal well bores. High concentrations of LCM, high rheological properties of fluids and low flow rates increase the changes of solving the first problem. The results of the second bench demonstrate the difficulties of annulus gas evacution for angles varying from 90 to 100 degrees, or from over-gauged sections in horizontal holes.

  16. Resonant Higgs boson pair production in the $hh\\rightarrow b\\bar{b} \\; WW \\rightarrow b\\bar{b} \\ell^+ \

    CERN Document Server

    Martín Lozano, Víctor; Park, Chan Beom

    2015-01-01

    Adding a scalar singlet provides one of the simplest extensions of the Standard Model. In this work we briefly review the latest constraints on the mass and mixing of the new Higgs boson and study its production and decay at the LHC. We mainly focus on double Higgs production in the $hh \\rightarrow b \\bar{b} WW \\rightarrow b \\bar{b} \\ell^+ \

  17. Search and Rescue Aircrewman/HH3F Flight Mechanic, 2-10. Military Curriculum Materials for Vocational and Technical Education.

    Science.gov (United States)

    Ohio State Univ., Columbus. National Center for Research in Vocational Education.

    This self-paced, individualized course, adapted from military curriculum materials for use in vocational and technical education, teaches students the skills needed to become a qualified avionics worker on the HH-3F helicopter. The course materials consist of three pamphlets: two student workbooks and a composite ground/flight syllabus. Each…

  18. Production of bifunctional proteins by Aspergillus awamori: Llama variable heavy chain antibody fragment (V-HH) R9 coupled to Arthromyces ramosus peroxidase (ARP)

    NARCIS (Netherlands)

    Joosten, V.; Roelofs, M.S.; Dries, van den N.; Goosen, T.; Verrips, C.T.; Hondel, van den C.A.M.J.J.; Lokman, B.C.

    2005-01-01

    The Arthromyces ramosus peroxidase gene (arp) was genetically fused to either the 5'- or 3'-terminal ends of the gene encoding llama variable heavy chain antibody fragment V-HH R9, resulting in the fusion expression cassettes ARP-R9 or R9-ARP. Aspergillus awamori transformants were obtained which

  19. Production of bifunctional proteins by Aspergillus awamori: Llama variable heavy chain antibody fragment (V-HH) R9 coupled to Arthromyces ramosus peroxidase (ARP)

    NARCIS (Netherlands)

    Joosten, V.; Roelofs, M.S.; Dries, van den N.; Goosen, T.; Verrips, C.T.; Hondel, van den C.A.M.J.J.; Lokman, B.C.

    2005-01-01

    The Arthromyces ramosus peroxidase gene (arp) was genetically fused to either the 5'- or 3'-terminal ends of the gene encoding llama variable heavy chain antibody fragment V-HH R9, resulting in the fusion expression cassettes ARP-R9 or R9-ARP. Aspergillus awamori transformants were obtained which pr

  20. Production of bifunctional proteins by Aspergillus awamori: Llama variable heavy chain antibody fragment (V-HH) R9 coupled to Arthromyces ramosus peroxidase (ARP)

    NARCIS (Netherlands)

    Joosten, V.; Roelofs, M.S.; Dries, van den N.; Goosen, T.; Verrips, C.T.; Hondel, van den C.A.M.J.J.; Lokman, B.C.

    2005-01-01

    The Arthromyces ramosus peroxidase gene (arp) was genetically fused to either the 5'- or 3'-terminal ends of the gene encoding llama variable heavy chain antibody fragment V-HH R9, resulting in the fusion expression cassettes ARP-R9 or R9-ARP. Aspergillus awamori transformants were obtained which pr

  1. Snapshots of the ``breaking” of the H-H bond in the oxidative addition of H2 to a metal centre

    Indian Academy of Sciences (India)

    Saikat Dutta; Balaji R Jagirdar

    2006-11-01

    Three new monocationic molecular hydrogen complexes of ruthenium of the type trans-[RuCl(2-H2)(PP)2][BF4] (PP = bis-1,2(diarylphosphino)ethane, aryl = -fluorobenzyl, benzyl, -methylbenzyl) have been prepared by protonating the precursor hydride complexes trans-[RuCl(H)(PP)2] using HBF4.Et2O. These three dihydrogen complexes are quite stable and have been isolated in the solid state. The intact nature of the H-H bond in these derivatives has been established from the short spin-lattice relaxation times (1, ) and the observation of substantial H, D couplings in the HD isotopomers. The H-H bond distances (HH, Å) increase from 0.97 to 1.01 Å as the electron donor ability of the diphosphine ligand increases from the -fluorobenzyl to the benzyl to the -methylbenzyl moiety. These dihydrogen complexes constitute the initial stages of elongation of the H-H bond enroute to its cleavage along the reaction coordinate for the oxidative addition of H2 to a metal centre.

  2. Male infertility: a public health issue caused by sexually transmitted pathogens.

    Science.gov (United States)

    Gimenes, Fabrícia; Souza, Raquel P; Bento, Jaqueline C; Teixeira, Jorge J V; Maria-Engler, Silvya S; Bonini, Marcelo G; Consolaro, Marcia E L

    2014-12-01

    Sexually transmitted diseases (STDs) are caused by several pathogens, including bacteria, viruses and protozoa, and can induce male infertility through multiple pathophysiological mechanisms. Additionally, horizontal transmission of STD pathogens to sexual partners or vertical transmission to fetuses and neonates is possible. Chlamydia trachomatis, Ureaplasma spp., human papillomavirus, hepatitis B and hepatitis C viruses, HIV-1 and human cytomegalovirus have all been detected in semen from symptomatic and asymptomatic men with testicular, accessory gland and urethral infections. These pathogens are associated with poor sperm quality and decreased sperm concentration and motility. However, the effects of these STD agents on semen quality are unclear, as are the effects of herpes simplex virus type 1 and type 2, Neisseria gonorrhoeae, Mycoplasma spp., Treponema pallidum and Trichomonas vaginalis, because few studies have evaluated the influence of these pathogens on male infertility. Chronic or inadequately treated infections seem to be more relevant to infertility than acute infections are, although in many cases the exact aetiological agents remain unknown.

  3. Sexually transmitted diseases and sexual function.

    Science.gov (United States)

    Sadeghi-Nejad, Hossein; Wasserman, Marlene; Weidner, Wolfgang; Richardson, Daniel; Goldmeier, David

    2010-01-01

    There is a need for state-of-the-art information in the area of sexually transmitted infections (STIs) in relation to sexual function. There are an estimated 60 million people living with and 340 million with treatable STIs. Surveys show sexual problems to be as high as 35% for men and 55% for women; however, there is little research directly assessing relationships between infection and sexual function. To show that STIs are associated with (and may cause) sexual dysfunction. Conversely, sexual dysfunction can increase patients' risk of STI acquisition. In men, erectile dysfunction (ED) associated with condom use may lead to unsafe sexual practices and, hence, STI acquisition. The role of various therapies including phosphodiesterase type 5 inhibitors in the treatment of ED in positive men taking social drugs will be explored. To provide state-of-the-art knowledge concerning sexual function and STIs, representing the opinions of five experts from four countries developed in a consensus process and encompassing a detailed literature review over a 2-year period. Expert opinion was based on the grading of evidence-based medical literature, widespread internal committee discussion, public presentation, and debate. This article highlights major factors causing the spread of STIs and suggests management interventions to prevent further spread of HIV/STIs, focusing on the juxtaposition between STIs and sexual functioning. Women's unique vulnerabilities to HIV/STIs (biological and physiological issues, gender-based violence, gender inequity) and their impact on women's sexual function are reviewed. Similarly, men's unique vulnerabilities to HIV/STIs including condom use, disclosure, voluntary counseling and testing, multiple concurrent sexual partners, and recreational drug use--particularly in homosexual men--are explored, as is the association of prostatitis and sexual function. Lastly, the article reviews the relationship between circumcision and sexual dysfunction. A

  4. Global epidemiology of sexually transmitted diseases

    Institute of Scientific and Technical Information of China (English)

    Carlos T. Da Ros; Caio da Silva Schmitt

    2008-01-01

    Sexually transmitted diseases (STDs) are among the first ten causes of unpleasant diseases in young adult males in developing countries and the second major cause of unpleasant diseases in young adult women. Adolescents and new acquired STDs. In general, STDs are epidemics and present an enormous health and economic consequences.An adequate screening for STDs should be done on a routine basis in every part of the world. Many STDs are asymptomatic and therefore can difficult to control. The purpose of reporting of STDs is to ensure that persons who are infected will be quickly diagnosed and appropriately treated to control the spread of infection and also so that partners are notified, tested and appropriately treated. It is estimated that reported cases of STDs represent only High-risk sexual behavior is a highly contributive factor of this process as it often leads to teenage pregnancies and HIV/AIDS. One possible explanation for this behavior is that people do not have enough information about the transmission of STDs or ignore the precautions required for safe sex. Approximately 60% of new HIV infections worldwide occur in young people. The frequency of high-risk behaviors among youths may also be influenced by opportunity to engage in them, particularly the amount of time that they are unsupervised by adults. However, in diagnosing and treating these patients, we can effectively prevent the spread of HIV/AIDS. Individuals infected with STDs are of the genital tract lining or skin creates a portal of entry for HIV and, hence, HIV-infected individuals with other STDs are more likely to shed HIV in their genital secretions. To date, the condom is the most effective method available for males for protection against STDs. It is important to control STDs, and prevention can be the key of this process. Prevention can be achieved through education of the population, identification of symptomatic and asymptomatic people, and effective diagnosis and treatment of these

  5. Esquistossomose: nova ocorrência de Biomphalaria straminea em Belo Horizonte, Minas Gerais Schistosomiasis: new occurrence of Biomphalaria straminea in Belo Horizonte, Minas Gerais

    Directory of Open Access Journals (Sweden)

    Cecília Pereira de Souza

    1996-12-01

    ; among 83 snails from F1, and exposed to LE, 10 (12.0% shed cercariae. Among 88 snails exposed to VGS, 10 (11.3% shed cercariae. In Belo Horizonte, schistosomiasis is transmitted by B. glabrata and B. tenagophila. However, currently there exists the risk of appearance of a focus in which B. straminea could be the host if prophylactic measures are not taken by the authorities responsible for the construction of a park and lake at that site.

  6. Integrated Reconfigurable High-Voltage Transmitting Circuit for CMUTs

    DEFF Research Database (Denmark)

    Llimos Muntal, Pere; Larsen, Dennis Øland; Jørgensen, Ivan Harald Holger

    2014-01-01

    -out and measurements are performed on the integrated circuit. The transmitting circuit is reconfigurable externally making it able to drive a wide variety of CMUTs. The transmitting circuit can generate several pulse shapes, pulse voltages up to 100 V, maximum pulse range of 50 V and frequencies up to 5 MHz. The area...

  7. Transfusion-transmitted infections: Existing and emerging pathogens

    Directory of Open Access Journals (Sweden)

    Kaur Paramjit

    2005-01-01

    Full Text Available In general, the risk of transfusion-transmitted infections has been greatly reduced today. However, blood-borne bacterial and parasitic infections and emerging infections transmitted through transfusion are an area of increasing concern. Implementation of stringent donor eligibility criteria, improved donor screening and more sophisticated as well as sensitive methods of antibody, antigen and viral genome detection, have virtually eliminated transfusion transmitted infection in developed countries. In developing countries like India, the risk of transfusion-transmitted infections is still considerable. A comprehensive MEDLINE search and review of relevant transfusion medicine literature were carried out and the data extracted and studied with particular reference to emerging pathogens transmitted through blood transfusion and posing a huge threat.

  8. [Sexually transmitted diseases (STD) and contraception].

    Science.gov (United States)

    Erny, R; Porte, H

    1989-06-01

    Sexually transmitted diseases (STDs) have shown a considerable resurgence in recent years both in number of cases and in spread of new infectious agents. The spread of STDs is favored by numerous factors including the liberalization of sexual behavior made possible by reliable contraception. Information on STDs has not been widely diffused. Changes in the status of women and the development of means of communication and transportation have encouraged less rigid control of sexual behavior. STDs themselves have often escaped diagnosis or not been cured despite treatment, increasing the risk of spread. Numerous organisms cause STDs, from external parasites to life-threatening viruses. 60% of upper genital tract infections that can lead to sterility, tubal alterations, ectopic pregnancy and pain result from STDs. Chlamydia infections are insidious and chronic, and cause greater damage with each recurrence. The risk of STDs should be considered in contraceptive choice along with other indications and contraindications. Combined oral contraceptives provide protection against acute upper genital tract infections. The protective role has been explained by scanty and highly viscous cervical mucus forming a barrier against germs and by reductions of menstrual flow, myometrial activity, and inflammation. It is actually uncertain whether combined oral contraceptives protect against latent chlamydia infections, since higher rates of cervicitis caused by chlamydia have been found in pill users. In situations carrying risk of STDs, pill users should be protected by a supplementary barrier method. IUDs have been implicated in numerous studies in acute pelvic infections. Possible explanations are the local trauma and inflammations due to the physical presence of the IUD, more abundant bleeding, absence of a cervical barrier to motile sperm that could be a vector for germs, and possible ascent of the infectious agent on the string. Other risk factors are involved. Epidemiologic

  9. Characteristics of Buoyancy Driven Natural Ventilation through Horizontal Openings

    DEFF Research Database (Denmark)

    Li, Zhigang

    and smoke. Air flow through vertical openings has been widely investigated but little is known about the flow in the horizontal openings, especially when they are driven by buoyancy. A literature survey shows that the brine-water system and the scale model are normally used forthe research work of air flow...... through horizontal openings. Two cases of full-scale measurements of buoyancy driven natural ventilation through horizontal openings are performed: one horizontal opening and one horizontal opening combined with one vertical opening. For the case of one horizontal opening, the measurements are made...

  10. The horizontal plane appearances of scoliosis

    DEFF Research Database (Denmark)

    Illés, Tamás S.; Burkus, Máté; Somoskeőy, Szabolcs

    2017-01-01

    Purpose: A posterior-anterior vertebral vector is proposed to facilitate visualization and understanding of scoliosis. The aim of this study was to highlight the interest of using vertebral vectors, especially in the horizontal plane, in clinical practice. Methods: We used an EOS two-/three-dimen......Purpose: A posterior-anterior vertebral vector is proposed to facilitate visualization and understanding of scoliosis. The aim of this study was to highlight the interest of using vertebral vectors, especially in the horizontal plane, in clinical practice. Methods: We used an EOS two...... of scoliosis. The approach used is simple. These results are sufficient for a first visual analysis furnishing significant clinical information in all three anatomical planes. This visualization represents a reasonable compromise between mathematical purity and practical use....

  11. Kinematics of horizontal and vertical caterpillar crawling.

    Science.gov (United States)

    van Griethuijsen, Linnea I; Trimmer, Barry A

    2009-05-01

    Unlike horizontal crawling, vertical crawling involves two counteracting forces: torque rotating the body around its center of mass and gravity resisting forward movement. The influence of these forces on kinematics has been examined in the soft-bodied larval stage of Manduca sexta. We found that crawling and climbing are accomplished using the same movements, with both segment timing and proleg lift indistinguishable in horizontal and vertical locomotion. Minor differences were detected in stride length and in the delay between crawls, which led to a lower crawling speed in the vertical orientation. Although these differences were statistically significant, they were much smaller than the variation in kinematic parameters between animals. The ability of Manduca to crawl and climb using the same movements is best explained by Manduca's relatively small size, slow speed and strong, controlled, passive grip made possible by its proleg/crochets.

  12. Detecting series periodicity with horizontal visibility graphs

    CERN Document Server

    Núñez, Angel M; Valero, Eusebio; Gómez, Jose Patricio; Luque, Bartolo

    2011-01-01

    The horizontal visibility algorithm has been recently introduced as a mapping between time series and networks. The challenge lies in characterizing the structure of time series (and the processes that generated those series) using the powerful tools of graph theory. Recent works have shown that the visibility graphs inherit several degrees of correlations from their associated series, and therefore such graph theoretical characterization is in principle possible. However, both the mathematical grounding of this promising theory and its applications are on its infancy. Following this line, here we address the question of detecting hidden periodicity in series polluted with a certain amount of noise. We first put forward some generic properties of horizontal visibility graphs which allow us to define a (graph theoretical) noise reduction filter. Accordingly, we evaluate its performance for the task of calculating the period of noisy periodic signals, and compare our results with standard time domain (autocorre...

  13. Buoyancy Driven Natural Ventilation through Horizontal Openings

    DEFF Research Database (Denmark)

    Heiselberg, Per; Li, Zhigang

    2009-01-01

    An experimental study of the phenomenon of buoyancy driven natural ventilation through single-sided horizontal openings was performed in a full-scale laboratory test rig. The measurements were made for opening ratios L/D ranging from 0.027 to 4.455, where L and D are the length of the opening...... and the diameter of the opening, respectively. The basic nature of airflow through single-sided openings, including airflow rate, air velocity, temperature difference between the rooms and the dimensions of the horizontal openings, were measured. A bi-directional airflow rate was measured using the constant...... injection tracer gas technique. Smoke visualizations showed that the airflow patterns are highly transient and unstable, and that the airflow rate oscillates with time. Correlations between the Froude (Archimedes) number Fr (Ar) and the L/D ratio are presented. In some cases the measured airflow rates fit...

  14. Horizontal Bilayer for Electrical and Optical Recordings

    Directory of Open Access Journals (Sweden)

    Alf Honigmann

    2012-12-01

    Full Text Available Artificial bilayer containing reconstituted ion channels, transporters and pumps serve as a well-defined model system for electrophysiological investigations of membrane protein structure–function relationship. Appropriately constructed microchips containing horizontally oriented bilayers with easy solution access to both sides provide, in addition, the possibility to investigate these model bilayer membranes and the membrane proteins therein with high resolution fluorescence techniques up to the single-molecule level. Here, we describe a bilayer microchip system in which long-term stable horizontal free-standing and hydrogel-supported bilayers can be formed and demonstrate its prospects particularly for single-molecule fluorescence spectroscopy and high resolution fluorescence microscopy in probing the physicochemical properties like phase behavior of the bilayer-forming lipids, as well as in functional studies of membrane proteins.

  15. Currencies of Mutualisms: Sources of Alkaloid Genes in Vertically Transmitted Epichloae

    Directory of Open Access Journals (Sweden)

    Christopher L. Schardl

    2013-06-01

    Full Text Available The epichloae (Epichloë and Neotyphodium species, a monophyletic group of fungi in the family Clavicipitaceae, are systemic symbionts of cool-season grasses (Poaceae subfamily Poöideae. Most epichloae are vertically transmitted in seeds (endophytes, and most produce alkaloids that attack nervous systems of potential herbivores. These protective metabolites include ergot alkaloids and indole-diterpenes (tremorgens, which are active in vertebrate systems, and lolines and peramine, which are more specific against invertebrates. Several Epichloë species have been described which are sexual and capable of horizontal transmission, and most are vertically transmissible also. Asexual epichloae are mainly or exclusively vertically transmitted, and many are interspecific hybrids with genomic contributions from two or three ancestral Epichloë species. Here we employ genome-scale analyses to investigate the origins of biosynthesis gene clusters for ergot alkaloids (EAS, indole-diterpenes (IDT, and lolines (LOL in 12 hybrid species. In each hybrid, the alkaloid-gene and housekeeping-gene relationships were congruent. Interestingly, hybrids frequently had alkaloid clusters that were rare in their sexual ancestors. Also, in those hybrids that had multiple EAS, IDT or LOL clusters, one cluster lacked some genes, usually for late pathway steps. Possible implications of these findings for the alkaloid profiles and endophyte ecology are discussed.

  16. HH 223: a parsec-scale H2 outflow in the star-forming region L723

    Science.gov (United States)

    López, R.; Acosta-Pulido, J. A.; Gómez, G.; Estalella, R.; Carrasco-González, C.

    2010-11-01

    Context. The dark cloud Lynds 723 (L723) is a low-mass star-forming region where one of the few known cases of a quadrupolar CO outflow has been reported. Two recent works have found that the radio continuum source VLA 2, towards the centre of the CO outflow, is actually a multiple system of young stellar objects (YSOs). Several line-emission nebulae that lie projected on the east-west CO outflow were detected in narrow-band Hα and [S ii] images. The spectra of the knots are characteristic of shock-excited gas (Herbig-Haro spectra), with supersonic blueshifted velocities, which suggests an optical outflow also powered by the VLA 2 YSO system of L723. Aims: Our aim is to study L723 in the near-infrared and look for line-emission nebulae associated with the optical and CO outflows. Methods: We imaged a field of ~5' × 5' centred on HH 223, which includes the whole region of the quadrupolar CO outflow with narrow-band filters centred on the [Fe ii] 1.644 μm and H2 2.122 μm lines, together with off-line Hc and Kc filters. The [Fe ii] and H2 line-emission structures were identified after extracting the continuum contribution, if any. Their positions were determined from an accurate astrometry of the images. Results: The H2 line-emission structures appear distributed over a region of 5.5 arcmin (~0.5 pc for a distance of 300 pc) at both sides of the VLA 2 YSO system, with an S-shape morphology, and are projected onto the east-west CO outflow. Most of them were resolved in smaller knotty substructures. The [Fe ii] emission only appears associated with HH 223. An additional nebular emission from the continuum in Hc and Kc appears associated with HH 223-K1, the structure closest to the VLA 2 YSO system, and could be tracing the cavity walls. Conclusions: We propose that the H2 structures form part of a large-scale near-infrared outflow, which is also associated with the VLA 2 YSO system. The current data do not allow us to discern which of the YSOs of VLA 2 is powering

  17. Gas reservoir evaluation for underbalanced horizontal drilling

    Directory of Open Access Journals (Sweden)

    Li Gao

    2014-01-01

    Full Text Available A set of surface equipment for monitoring the parameters of fluid and pressure while drilling was developed, and mathematical models for gas reservoir seepage and wellbore two-phase flow were established. Based on drilling operation parameters, well structure and monitored parameters, the wellbore pressure and the gas reservoir permeability could be predicted theoretically for underbalanced horizontal drilling. Based on the monitored gas production along the well depth, the gas reservoir type could be identified.

  18. Horizontal Symmetry: Bottom Up and Top Down

    CERN Document Server

    Lam, C S

    2011-01-01

    A group-theoretical connection between horizontal symmetry $\\G$ and fermion mixing is established, and applied to neutrino mixing. The group-theoretical approach is consistent with a dynamical theory based on $U(1)\\times \\G$, but the dynamical theory can be used to pick out the most stable mixing that purely group-theoretical considerations cannot. A symmetry common to leptons and quarks is also discussed. This higher symmetry picks $A_4$ over $S_4$ to be the preferred symmetry for leptons.

  19. Convection in horizontally shaken granular material

    OpenAIRE

    Saluena, Clara; Poeschel, Thorsten

    1998-01-01

    In horizontally shaken granular material different types of pattern formation have been reported. We want to deal with the convection instability which has been observed in experiments and which recently has been investigated numerically. Using two dimensional molecular dynamics we show that the convection pattern depends crucial on the inelastic properties of the material. The concept of restitution coefficient provides arguments for the change of the behaviour with variing inelasticity.

  20. R&D investments fostering horizontal mergers

    OpenAIRE

    Cabolis, C.; Manasakis, C.; MORENO, Diego; Petrakis, Emmanuel

    2016-01-01

    We study a homogenous good triopoly in which firms first choose their cost-reducing R&D investments and consider alternative merger proposals, and then compete à la Cournot in the ensuing industry. We identify conditions under which both horizontal mergers and non integration are sustained by Coalition-Proof Nash equilibria (CPNE). These conditions involve the effectiveness of the R&D technology, as well as the distribution of the bargaining power between the acquirer and the acquiree, which ...

  1. Horizontal rays and vertical modes method for the computation of the vertical propagation of acoustic-gravity waves

    Science.gov (United States)

    Lahaye, Noé; Smith, Stefan Llewellyn

    2016-04-01

    We consider the vertical propagation of acoustic-gravity waves generated by a finite-size perturbation at the bottom, through a moving inhomogeneous atmosphere. Under the hypothesis of weak inhomogeneities in the horizontal direction, an approximate solution is obtained in terms of normal modes and horizontal rays. The problem is thus reduced to a depth-separated equation very similar to the standard Taylor-Goldstein equation, with weak dependence of the parameters on the horizontal coordinates, and to ray equations along the horizontal -- thus decreasing the computational resources needed. One advantage of this method is to retain the signal that is partially transmitted across reflecting regions that may exist due to the background wind jet, contrary to standard ray tracing that would predict pure reflexion. In addition, the limitation to an homogeneous medium along the horizontal coordinates that applies to other standard methods based on spectral integral transforms is released with the current approach. An idealized configuration is investigated, where numerical results are shown. Finally, a more general formulation in terms of approximate adiabatic spectral integral transform is presented. Implications for the computation of the propagation of Tsunami-generated acoustic-gravity waves, and more generally waves generated at the bottom of an inhomogeneous moving fluid, are discussed.

  2. Thermal transient analysis applied to horizontal wells

    Energy Technology Data Exchange (ETDEWEB)

    Duong, A.N. [Society of Petroleum Engineers, Canadian Section, Calgary, AB (Canada)]|[ConocoPhillips Canada Resources Corp., Calgary, AB (Canada)

    2008-10-15

    Steam assisted gravity drainage (SAGD) is a thermal recovery process used to recover bitumen and heavy oil. This paper presented a newly developed model to estimate cooling time and formation thermal diffusivity by using a thermal transient analysis along the horizontal wellbore under a steam heating process. This radial conduction heating model provides information on the heat influx distribution along a horizontal wellbore or elongated steam chamber, and is therefore important for determining the effectiveness of the heating process in the start-up phase in SAGD. Net heat flux estimation in the target formation during start-up can be difficult to measure because of uncertainties regarding heat loss in the vertical section; steam quality along the horizontal segment; distribution of steam along the wellbore; operational conditions; and additional effects of convection heating. The newly presented model can be considered analogous to pressure transient analysis of a buildup after a constant pressure drawdown. The model is based on an assumption of an infinite-acting system. This paper also proposed a new concept of a heating ring to measure the heat storage in the heated bitumen at the time of testing. Field observations were used to demonstrate how the model can be used to save heat energy, conserve steam and enhance bitumen recovery. 18 refs., 14 figs., 2 appendices.

  3. Vertical and horizontal seismometric observations of tides

    Science.gov (United States)

    Lambotte, S.; Rivera, L.; Hinderer, J.

    2006-01-01

    Tidal signals have been largely studied with gravimeters, strainmeters and tiltmeters, but can also be retrieved from digital records of the output of long-period seismometers, such as STS-1, particularly if they are properly isolated. Horizontal components are often noisier than the vertical ones, due to sensitivity to tilt at long periods. Hence, horizontal components are often disturbed by local effects such as topography, geology and cavity effects, which imply a strain-tilt coupling. We use series of data (duration larger than 1 month) from several permanent broadband seismological stations to examine these disturbances. We search a minimal set of observable signals (tilts, horizontal and vertical displacements, strains, gravity) necessary to reconstruct the seismological record. Such analysis gives a set of coefficients (per component for each studied station), which are stable over years and then can be used systematically to correct data from these disturbances without needing heavy numerical computation. A special attention is devoted to ocean loading for stations close to oceans (e.g. Matsushiro station in Japon (MAJO)), and to pressure correction when barometric data are available. Interesting observations are made for vertical seismometric components; in particular, we found a pressure admittance between pressure and data 10 times larger than for gravimeters for periods larger than 1 day, while this admittance reaches the usual value of -3.5 nm/s 2/mbar for periods below 3 h. This observation may be due to instrumental noise, but the exact mechanism is not yet understood.

  4. Cable Modems' Transmitted RF: A Study of SNR, Error Rates, Transmit Levels, and Trouble Call Metrics

    Science.gov (United States)

    Tebbetts, Jo A.

    2013-01-01

    Hypotheses were developed and tested to measure the cable modems operational metrics response to a reconfiguration of the cable modems' transmitted RF applied to the CMTS. The purpose of this experiment was to compare two groups on the use of non-federal RF spectrum to determine if configuring the cable modems' transmitted RF from 25.2…

  5. Two Component Decomposition of Dual Polarimetric HH/VV SAR Data: Case Study for the Tundra Environment of the Mackenzie Delta Region, Canada

    Directory of Open Access Journals (Sweden)

    Tobias Ullmann

    2016-12-01

    Full Text Available This study investigates a two component decomposition technique for HH/VV-polarized PolSAR (Polarimetric Synthetic Aperture Radar data. The approach is a straight forward adaption of the Yamaguchi decomposition and decomposes the data into two scattering contributions: surface and double bounce under the assumption of a negligible vegetation scattering component in Tundra environments. The dependencies between the features of this two and the classical three component Yamaguchi decomposition were investigated for Radarsat-2 (quad and TerraSAR-X (HH/VV data for the Mackenzie Delta Region, Canada. In situ data on land cover were used to derive the scattering characteristics and to analyze the correlation among the PolSAR features. The double bounce and surface scattering features of the two and three component scattering model (derived from pseudo-HH/VV- and quad-polarized data showed similar scattering characteristics and positively correlated-R2 values of 0.60 (double bounce and 0.88 (surface scattering were observed. The presence of volume scattering led to differences between the features and these were minimized for land cover classes of low vegetation height that showed little volume scattering contribution. In terms of separability, the quad-polarized Radarsat-2 data offered the best separation of the examined tundra land cover types and will be best suited for the classification. This is anticipated as it represents the largest feature space of all tested ones. However; the classes “wetland” and “bare ground” showed clear positions in the feature spaces of the C- and X-Band HH/VV-polarized data and an accurate classification of these land cover types is promising. Among the possible dual-polarization modes of Radarsat-2 the HH/VV was found to be the favorable mode for the characterization of the aforementioned tundra land cover classes due to the coherent acquisition and the preserved co-pol. phase. Contrary, HH/HV-polarized and VV

  6. Sexually transmitted diseases among psychiatric patients in Brazil.

    Science.gov (United States)

    Dutra, Maria Rita Teixeira; Campos, Lorenza Nogueira; Guimarães, Mark Drew Crosland

    2014-01-01

    Sexually transmitted diseases are still highly prevalent worldwide and represent an important public health problem. Psychiatric patients are at increased risk of sexually transmitted diseases but there are scarce published studies with representative data of this population. We sought to estimate the prevalence and correlates of self-reported sexually transmitted diseases among patients with mental illnesses under care in a national representative sample in Brazil (n=2145). More than one quarter of the sample (25.8%) reported a lifetime history of sexually transmitted disease. Multivariate analyses showed that patients with a lifetime sexually transmitted disease history were older, had history of homelessness, used more alcohol and illicit drugs, suffered violence, perceived themselves to be at greater risk for HIV and had high risk sexual behavioral: practised unprotected sex, started sexual life earlier, had more than ten sexual partners, exchanged money and/or drugs for sex and had a partner that refused to use condom. Our findings indicate a high prevalence of self-reported sexually transmitted diseases among psychiatric patients in Brazil, and emphasize the need for implementing sexually transmitted diseases prevention programs in psychiatric settings, including screening, treatment, and behavioral modification interventions.

  7. Sexually transmitted diseases among psychiatric patients in Brazil

    Directory of Open Access Journals (Sweden)

    Maria Rita Teixeira Dutra

    2014-01-01

    Full Text Available Sexually transmitted diseases are still highly prevalent worldwide and represent an important public health problem. Psychiatric patients are at increased risk of sexually transmitted diseases but there are scarce published studies with representative data of this population. We sought to estimate the prevalence and correlates of self-reported sexually transmitted diseases among patients with mental illnesses under care in a national representative sample in Brazil (n = 2145. More than one quarter of the sample (25.8% reported a lifetime history of sexually transmitted disease. Multivariate analyses showed that patients with a lifetime sexually transmitted disease history were older, had history of homelessness, used more alcohol and illicit drugs, suffered violence, perceived themselves to be at greater risk for HIV and had high risk sexual behavioral: practised unprotected sex, started sexual life earlier, had more than ten sexual partners, exchanged money and/or drugs for sex and had a partner that refused to use condom. Our findings indicate a high prevalence of self-reported sexually transmitted diseases among psychiatric patients in Brazil, and emphasize the need for implementing sexually transmitted diseases prevention programs in psychiatric settings, including screening, treatment, and behavioral modification interventions.

  8. Genetics Home Reference: horizontal gaze palsy with progressive scoliosis

    Science.gov (United States)

    ... Health Conditions HGPPS horizontal gaze palsy with progressive scoliosis Printable PDF Open All Close All Enable Javascript ... collapse boxes. Description Horizontal gaze palsy with progressive scoliosis ( HGPPS ) is a disorder that affects vision and ...

  9. Integrated reconfigurable high-voltage transmitting circuit for CMUTs

    DEFF Research Database (Denmark)

    Llimos Muntal, Pere; Larsen, Dennis Øland; Jørgensen, Ivan Harald Holger

    2015-01-01

    In this paper a high-voltage transmitting circuit aimed for capacitive micromachined ultrasonic transducers (CMUTs) used in scanners for medical applications is designed and implemented in a 0.35 μm high-voltage CMOS process. The transmitting circuit is reconfigurable externally making it able...... performance. The design occupies an on-chip area of 0.938 mm2 and the power consumption of a 128-element transmitting circuit array that would be used in an portable ultrasound scanner is found to be a maximum of 181 mW....

  10. Integrated reconfigurable high-voltage transmitting circuit for CMUTs

    DEFF Research Database (Denmark)

    Llimos Muntal, Pere; Larsen, Dennis Øland; Jørgensen, Ivan Harald Holger;

    2015-01-01

    In this paper a high-voltage transmitting circuit aimed for capacitive micromachined ultrasonic transducers (CMUTs) used in scanners for medical applications is designed and implemented in a 0.35 μm high-voltage CMOS process. The transmitting circuit is reconfigurable externally making it able...... performance. The design occupies an on-chip area of 0.938 mm2 and the power consumption of a 128-element transmitting circuit array that would be used in an portable ultrasound scanner is found to be a maximum of 181 mW....

  11. Studying the Outflow-Core Interaction with ALMA Cycle 1 Observations of the HH 46/47 Molecular Outflow

    CERN Document Server

    Zhang, Yichen; Mardones, Diego; Cabrit, Sylvie; Dunham, Michael M; Garay, Guido; Noriega-Crespo, Alberto; Offner, Stella S R; Raga, Alejandro C; Corder, Stuartt A

    2016-01-01

    We present ALMA Cycle 1 observations of the HH 46/47 molecular outflow using combined 12m array and 7m array observations. We use 13CO and C18O emission to correct for the 12CO optical depth, to accurately estimate the outflow mass, momentum and kinetic energy. Applying the optical depth correction increases the mass estimate by a factor of 14, the momentum by a factor of 6, and the kinetic energy by a factor of about 2. The new 13CO(1-0) and C18O(1-0) data also allow us to trace denser and slower outflow material than that traced by 12CO. These species are only detected within about 1~2 km/s from the cloud velocity. The cavity wall of the red lobe appears at very low velocities (~0.2 km/s). Combing the material traced only by 13CO and C18O, the measured total mass of the CO outflow is 1.4 Msun, the total momentum is 1.7 Msun km/s and the total energy is 4.7e43 erg, assuming Tex=15 K. The improved angular resolution and sensitivity in 12CO reveal more details of the outflow structure. Specifically, we find th...

  12. HH 666: Different kinematics from H{\\alpha} and [Fe II] emission provide a missing link between jets and outflows

    CERN Document Server

    Reiter, Megan; Kiminki, Megan M; Bally, John

    2015-01-01

    HH 666 is an externally irradiated protostellar outflow in the Carina Nebula for which we present new near-IR [Fe II] spectra obtained with the FIRE spectrograph at Magellan Observatory. Earlier H{\\alpha} and near-IR [Fe II] imaging revealed that the two emission lines trace substantially different morphologies in the inner ~40" of the outflow. H{\\alpha} traces a broad cocoon that surrounds the collimated [Fe II] jet that extends throughout the parent dust pillar. New spectra show that this discrepancy extends to their kinematics. Near-IR [Fe II] emission traces steady, fast velocities of +/- 200 km/s from the eastern and western limbs of the jet. We compare this to a previously published H{\\alpha} spectrum that reveals a Hubble-flow velocity structure near the jet-driving source. New, second-epoch HST/ACS H{\\alpha} images reveal the lateral spreading of the H{\\alpha} outflow lobe away from the jet axis. H{\\alpha} proper motions also indicate a sudden increase in the mass-loss rate ~1000 yr ago, while steady ...

  13. KK MC-hh: Resumed exact O (α2L ) EW corrections in a hadronic MC event generator

    Science.gov (United States)

    Jadach, S.; Ward, B. F. L.; Was, Z. A.; Yost, S. A.

    2016-10-01

    We present an improvement of the Monte Carlo (MC) event generator Herwiri2, where we recall the latter MC was a prototype for the inclusion of CEEX resummed electroweak (EW) corrections in hadron-hadron scattering at high center of momentum system (cms) energies. In this improvement the new exact O (α2L ) resummed EW generator K K MC 4.22, featuring as it does the CEEX realization of resummation in the EW sector, is put in union with the Herwig parton shower environment. The Les Houches (LHE) format of the attendant output event file means that all other conventional parton shower environments are available to the would-be user of the resulting new MC. For this reason (and others—see the text) we henceforth refer to the new improvement of the Herwiri2 MC as K K MC -hh. Since this new MC features exact O (α ) pure weak corrections from the DIZET EW library and features the CEEX and the EEX YFS-style resummation of large multiple photon effects, it provides already the concrete path to 0.05% precision on such effects if we focus on the EW effects themselves. We therefore show predictions for observable distributions and comparisons with other approaches in the literature. This MC represents an important step in the realization of the exact amplitude-based QED ⊗QCD resummation paradigm. Independently of this latter observation, the MC rigorously quantifies important EW effects in the current LHC experiments.

  14. One-parameter cascade model of multiple hadrons production in inelastic hh-processes at high energies

    Energy Technology Data Exchange (ETDEWEB)

    Rusov, V.D. [Department of Theoretical and Experimental Nuclear Physics, Odessa National Polytechnic University, Shevchenko av. 1, Odessa 65044 (Ukraine)]. E-mail: siiis@te.net.ua; Sharf, I.V. [Department of Theoretical and Experimental Nuclear Physics, Odessa National Polytechnic University, Shevchenko av. 1, Odessa 65044 (Ukraine)

    2006-01-09

    The inhomogeneous cascade-stochastic model of multiple hadrons production in inelastic p-bar p- and pp-interactions at high energies is proposed. In this model inclusive rapidity distributions of secondary hadrons are used as input data. One-parameter cascade-stochastic multiplicity distribution, where adjustable parameter has sense of the height of Feynman plateau of inclusive rapidity distribution of secondary hadrons in one hadron shower, is obtained. It is shown that all known now experimental data concerning both multiplicity and rapidity distributions of secondary particles in inelastic hh-processes in energy range s=30-1800 GeV, and also the ratio of cumulant moments to factorial moments of the multiplicity distributions in energy range s=200-900 GeV are described with high accuracy by one-parameter cascade-stochastic model of multiple hadrons production. The explicit form of asymptotic of distributions as well-known Polyakov-Dokshitzer's scaling function for quark and gluon jets is obtained by fitting of prognosis multiplicity distributions at energies s=14-30 TeV. A simplified quantitative analysis is presented and the qualitative explanation of behavior features of forward-backward multiplicity correlations is given within the framework of proposed model.

  15. Origin of the hot gas in low-mass protostars: Herschel-PACS spectroscopy of HH 46

    CERN Document Server

    van Kempen, T A; Herczeg, G J; Visser, R; van Dishoeck, E F; Wampfler, S F; Bruderer, S; Benz, A O; Doty, S D; Brinch, C; Hogerheijde, M R; Jørgensen, J K; Tafalla, M; Neufeld, D; Bachiller, R; Baudry, A; Benedettini, M; Bergin, E A; Bjerkeli, P; Blake, G A; Bontemps, S; Braine, J; Caselli, P; Cernicharo, J; Codella, C; Daniel, F; di Giorgio, A M; Dominik, C; Encrenaz, P; Fich, M; Fuente, A; Giannini, T; Goicoechea, J R; de Graauw, Th; Helmich, F; Herpin, F; Jacq, T; Johnstone, D; Kaufman, M J; Larsson, B; Lis, D; Liseau, R; Marseille, M; McCoey, C; Melnick, G; Nisini, B; Olberg, M; Parise, B; Pearson, J C; Plume, R; Risacher, C; Santiago-Garcia, J; Saraceno, P; Shipman, R; van der Tak, F; Wyrowski, F; Yildiz, U A; Ciechanowicz, M; Dubbeldam, L; Glenz, S; Huisman, R; Lin, R H; Morris, P; Murphy, J A; Trappe, N

    2010-01-01

    'Water in Star-forming regions with Herschel' (WISH) is a Herschel Key Programme aimed at understanding the physical and chemical structure of young stellar objects (YSOs) with a focus on water and related species. The low-mass protostar HH 46 was observed with the Photodetector Array Camera and Spectrometer (PACS) on the Herschel Space Observatory to measure emission in H2O, CO, OH, [OI], and [CII] lines located between 63 and 186 um. The excitation and spatial distribution of emission can disentangle the different heating mechanisms of YSOs, with better spatial resolution and sensitivity than previously possible. Far-IR line emission is detected at the position of the protostar and along the outflow axis. The OH emission is concentrated at the central position, CO emission is bright at the central position and along the outflow, and H2O emission is concentrated in the outflow. In addition, [OI] emission is seen in low-velocity gas, assumed to be related to the envelope, and is also seen shifted up to 170 km...

  16. X-ray emission from stellar jets by collision against high-density molecular clouds: an application to HH 248

    CERN Document Server

    Lopez-Santiago, Javier; Orellana, Mariana; Miceli, Marco; Orlando, Salvatore; Ustamujic, Sabina; Albacete-Colombo, Juan Facundo; de Castro, Elisa; de Castro, Ana Ines Gomez

    2015-01-01

    We investigate the plausibility of detecting X-ray emission from a stellar jet that impacts against a dense molecular cloud. This scenario may be usual for classical T Tauri stars with jets in dense star-forming complexes. We first model the impact of a jet against a dense cloud by 2D axisymmetric hydrodynamic simulations, exploring different configurations of the ambient environment. Then, we compare our results with XMM-Newton observations of the Herbig-Haro object HH 248, where extended X-ray emission aligned with the optical knots is detected at the edge of the nearby IC 434 cloud. Our simulations show that a jet can produce plasma with temperatures up to 10 MK, consistent with production of X-ray emission, after impacting a dense cloud. We find that jets denser than the ambient medium but less dense than the cloud produce detectable X-ray emission only at the impact onto the cloud. From the exploration of the model parameter space, we constrain the physical conditions (jet density and velocity, cloud den...

  17. Late-time spectroscopy of SN 2002hh: A continued visible light echo with no shock interaction yet

    CERN Document Server

    Andrews, Jennifer E; Mauerhan, Jon C

    2015-01-01

    Supernova (SN) 2002hh was unusual among core-collapse SNe because it was highly reddened, and displayed a bright infrared (IR) excess due to radiatively heated dust in its circumstellar medium (CSM). Estimates for the mass of dust responsible for the IR echo suggested the presence of a massive shell within 0.26 pc of the star. For a velocity of 5000 - 10000 km/s, this material should be hit by the SN blast wave at late times, starting at roughly 12 years post-explosion. We have obtained deep late-time spectra with the MMT Blue Channel spectrograph to search for any spectral signatures of ongoing shock interaction. Interaction with a strength comparable to SN 1987A's collision with the equatorial ring would be detected in our data. However, in the spectra reported here, we do not detect clear signs of strong CSM interaction, contrary to expectations based on the reported radii of the dust shell. We do, however, detect emission associated with the old SN, and we find that the broad lines in the spectrum indicat...

  18. Late-time spectroscopy of SN 2002hh: a continued visible light echo with no shock interaction yet

    Science.gov (United States)

    Andrews, J. E.; Smith, Nathan; Mauerhan, Jon C.

    2015-08-01

    Supernova (SN) 2002hh was unusual among core-collapse SNe because it was highly reddened, and displayed a bright infrared (IR) excess due to radiatively heated dust in its circumstellar medium (CSM). Estimates for the mass of dust responsible for the IR echo suggested the presence of a massive shell within 0.26 pc of the star. For a velocity of 5000-10 000 km s-1, this material should be hit by the SN blast wave at late times, starting at roughly 12 years post-explosion. We have obtained deep late-time spectra with the Multiple Mirror Telescope (MMT) Blue Channel spectrograph to search for any spectral signatures of ongoing shock interaction. Interaction with a strength comparable to SN 1987A's collision with the equatorial ring would be detected in our data. However, in the spectra reported here, we do not detect clear signs of strong CSM interaction, contrary to expectations based on the reported radii of the dust shell. We do, however, detect emission associated with the old SN, and we find that the broad lines in the spectrum indicate a continuation of an ongoing reflected light echo, which appears similar to the spectrum at peak luminosity for this Type II-P event.

  19. HH 223: a parsec-scale H2 outflow in the star-forming region L723

    CERN Document Server

    Lopez, R; Gomez, G; Estalella, R; Carrasco-Gonzalez, C

    2010-01-01

    The dark cloud Lynds 723 (L723) is a low-mass star-forming region where one of the few known cases of a quadrupolar CO outflow has been reported. Two recent works have found that the radio continuum source VLA 2, towards the centre of the CO outflow, is actually a multiple system of young stellar objects (YSOs). Several line-emission nebulae that lie projected on the east-west CO outflow were detected in narrow-band Halpha and [SII] images. The spectra of the knots are characteristic of shock-excited gas (Herbig-Haro spectra), with supersonic blueshifted velocities, which suggests an optical outflow also powered by the VLA 2 YSO system of L723. We imaged a field of ~5' X 5' centred on HH 223, which includes the whole region of the quadrupolar CO outflow with nir narrow-band filters . The H2 line-emission structures appear distributed over a region of 5.5' (0.5 pc for a distance of 300 pc) at both sides of the VLA 2 YSO system, with an S-shape morphology, and are projected onto the east-west CO outflow. Most o...

  20. Di-Higgs final states augMT2ed – Selecting hh events at the high luminosity LHC

    Energy Technology Data Exchange (ETDEWEB)

    Barr, Alan J., E-mail: a.barr@physics.ox.ac.uk [Denys Wilkinson Building, Department of Physics, Keble Road, Oxford, OX1 3RH (United Kingdom); Dolan, Matthew J., E-mail: m.j.dolan@durham.ac.uk [Institute for Particle Physics Phenomenology, Department of Physics, Durham University, DH1 3LE (United Kingdom); Englert, Christoph, E-mail: christoph.englert@glasgow.ac.uk [SUPA, School of Physics and Astronomy, University of Glasgow, Glasgow, G12 8QQ (United Kingdom); Spannowsky, Michael, E-mail: michael.spannowsky@durham.ac.uk [Institute for Particle Physics Phenomenology, Department of Physics, Durham University, DH1 3LE (United Kingdom)

    2014-01-20

    Higgs boson self-interactions can be investigated via di-Higgs (pp→hh+X) production at the LHC. With a small O(30) fb Standard Model production cross section, and a large tt{sup ¯} background, this measurement has been considered challenging, even at a luminosity-upgraded LHC. We demonstrate that by using simple kinematic bounding variables, of the sort already employed in existing LHC searches, the dominant tt{sup ¯} background can be largely eliminated. Simulations of the signal and the dominant background demonstrate the prospect for measurement of the di-Higgs production cross section at the 30% level using 3 ab{sup −1} of integrated luminosity at a high luminosity LHC. This corresponds to a Higgs self-coupling determination with 60% accuracy in the bb{sup ¯}τ{sup +}τ{sup −} mode, with potential for further improvements from e.g. subjet technologies and from additional di-Higgs decay channels.

  1. The Sinorhizobium (Ensifer) fredii HH103 Type 3 Secretion System Suppresses Early Defense Responses to Effectively Nodulate Soybean.

    Science.gov (United States)

    Jiménez-Guerrero, Irene; Pérez-Montaño, Francisco; Monreal, José Antonio; Preston, Gail M; Fones, Helen; Vioque, Blanca; Ollero, Francisco Javier; López-Baena, Francisco Javier

    2015-07-01

    Plants that interact with pathogenic bacteria in their natural environments have developed barriers to block or contain the infection. Phytopathogenic bacteria have evolved mechanisms to subvert these defenses and promote infection. Thus, the type 3 secretion system (T3SS) delivers bacterial effectors directly into the plant cells to alter host signaling and suppress defenses, providing an appropriate environment for bacterial multiplication. Some rhizobial strains possess a symbiotic T3SS that seems to be involved in the suppression of host defenses to promote nodulation and determine the host range. In this work, we show that the inactivation of the Sinorhizobium (Ensifer) fredii HH103 T3SS negatively affects soybean nodulation in the early stages of the symbiotic process, which is associated with a reduction of the expression of early nodulation genes. This symbiotic phenotype could be the consequence of the bacterial triggering of soybean defense responses associated with the production of salicylic acid (SA) and the impairment of the T3SS mutant to suppress these responses. Interestingly, the early induction of the transcription of GmMPK4, which negatively regulates SA accumulation and defense responses in soybean via WRKY33, could be associated with the differential defense responses induced by the parental and the T3SS mutant strain.

  2. Study of the Local Horizon. (Spanish Title: Estudio del Horizonte Local.) Estudo do Horizonte Local

    Science.gov (United States)

    Ros, Rosa M.

    2009-12-01

    The study of the horizon is fundamental to easy the first observations of the students at any education center. A simple model, to be developed in each center, allows to easy the study and comprehension of the rudiments of astronomy. The constructed model is presented in turn as a simple equatorial clock, other models (horizontal and vertical) may be constructed starting from it. El estudio del horizonte es fundamental para poder facilitar las primeras observaciones de los alumnos en un centro educativo. Un simple modelo, que debe realizarse para cada centro, nos permite facilitar el estudio y la comprensión de los primeros rudimentos astronómicos. El modelo construido se presenta a su vez como un sencillo modelo de reloj ecuatorial y a partir de él se pueden construir otros modelos (horizontal y vertical). O estudo do horizonte é fundamental para facilitar as primeiras observações dos alunos num centro educativo. Um modelo simples, que deve ser feito para cada centro, permite facilitar o estudo e a compreensão dos primeiros rudimentos astronômicos. O modelo construído apresenta-se, por sua vez, como um modelo simples de relógio equatorial e a partir dele pode-se construir outros modelos (horizontal e vertical)

  3. Horizontal routes: current paths of literary criticism in Latin America

    Directory of Open Access Journals (Sweden)

    Ariadne Costa da Mata

    2013-07-01

    Full Text Available In the last decades, the tendency towards horizontality became visible, particularly (but not only in social movements. Horizontality implies a new architecture in human organizations and pushes for changes in the way knowledge is produced and organized. More than a simple erosion of frontiers between fields, horizontality means the decentralization and dissemination of power.

  4. Application of Horizontal Well Technology to Liaohe Oilfield

    Institute of Scientific and Technical Information of China (English)

    HanYun

    2008-01-01

    @@ Horizontal well technology has become one of the main technologies enabling Liaohe Oilfield to realize stable development. By the end of 2006, 296 horizontal wells of various kinds had been completed in Liaohe Oil Field,273 wells had been put into production, Among uhich 237 were horizontal wells (see Table 1).

  5. YPF uses horizontal reentry to aid thin bed production

    Energy Technology Data Exchange (ETDEWEB)

    Acosta, M.R.; Leiro, F.A.; Sesano, G.S. [Yacimientos Petroliferos Fiscales, La Paz (Bolivia); Hill, D.

    1997-01-01

    Reentry and horizontal drilling/completion techniques have proven themselves useful in exploiting thin beds. A pilot horizontal reentry contracted by Yacimiento Petroliferos Fiscales (YPF) for a marginal well in its Lomita Sur field resulted in decreased water coning and production rates four times greater than expected. Further horizontal reentries in this thin-bed field are planned.

  6. High pressure investigations on hydrous magnesium silicate-phase A using first principles calculations: H---H repulsion and changes in hydrogen bond geometry with compression

    Science.gov (United States)

    Poswal, H. K.; Sharma, Surinder; Sikka, S. K.

    2009-09-01

    We have carried out first principles structural relaxation calculations on the hydrous magnesium silicate Phase A (Mg7Si2O8(OH)6) under high pressures. Our results show that phase A does not undergo any phase transition upto ~ 45 GPa. We find that non-bonded H--H distance reaches a limiting value of 1.85 angstrom at about 45 GPa. The H--H repulsive strain releasing mechanism in Phase A is found to be dramatically different from the hydrogen bond bending one that was proposed by Hofmeister et al1 for Phase B. It is based on the reduction of one of the O-H bond distances with compression.

  7. Horizontal distribution of mixed cloud type scene

    Science.gov (United States)

    Guillaume, A.; Kahn, B. H.; Yue, Q.; Wong, S.; Manipon, G.; Hua, H.; Wilson, B. D.; Wang, T.; Fetzer, E. J.

    2016-12-01

    We describe a novel method to uniquely characterize and quantify the scale dependence of mixed cloud scene geometry using cloud type classification reported with the 94GHz CloudSat radar. Only a fraction of all possible combinations of cloud types are observed at any along-track length scale considered. Cloud scenes most frequently contain only one or two cloud types. We show how cloud occurrence depends on the grid cell spatial resolution used to define cloud scenes. A maximum number of observed cloud scenes occur near 100 km with fewer cloud type combinations at smaller and larger scales. We then quantify the cloud lengths along the CloudSat track using both the cloud top classification and the vertical structure of cloud classification separately for each of the nine cloud types defined by CloudSat and for all clouds considered independent of cloud type. While the individual cloud types do not follow a clear power law behavior as a function of horizontal or vertical scale, a robust power law scaling of cloud geometry is observed when cloud type is not considered. The power law scaling exponent of horizontal length is approximated by β ≈ -5/3 over two to three orders of magnitude. The power law scaling exponent of vertical length is approximated by β ≈ -7/3 over two orders of magnitude. These exponents are in agreement with previous studies using numerical models, satellite, and in situ aircraft observations. In particular, the anisotropy in the horizontal and vertical scaling are nearly identical to recent aircraft observations of wind kinetic energy spectra, suggesting the underlying three-dimensional cloud geometry is strongly related to kinetic energy spectra.

  8. Variation in terminology: capoeira in Belo Horizonte

    Directory of Open Access Journals (Sweden)

    César Nardelli Cambraia

    2014-12-01

    Full Text Available In this pilot study we analyzed the variation in the terminology of capoeira in Belo Horizonte. The terms referring to 69 videotaped movements of capoeira were collected from 10 informants (5 men and 5 women, aged between 25 and 32 years, capoeira teachers. As a result we obtained 294 different terms whose patterns of variation are distributed among 15 types. We tested the hypothesis that the figurative terms tend to be replaced by non-figurative ones, and it was confirmed by the collected data. This trend was the result of a search for transparency in terminology, making the terms more descriptive in relation to capoeira’s movements.

  9. Impulse absorption by horizontal magnetic granular chain

    Directory of Open Access Journals (Sweden)

    Dingxin Leng

    2016-02-01

    Full Text Available The granular medium is known as a protecting material for shock mitigation. We study the impulse absorption of an alignment of magnetic spheres placed horizontally under a non-uniform magnetic field. The phenomenon of the wave dispersion is presented. This system can absorb 85% ∼ 95% (88% ∼ 98% of the incident peak force (energy under the applied magnetic field strength in 0.1 T ∼ 1.0 T. The shock attenuation capacities are enhanced by the increment of field strength. With an intelligent control system, it is conceivable that the magnetic granular chain may offer possibilities in developing adaptive shock protectors.

  10. Does horizontal transmission invalidate cultural phylogenies?

    Science.gov (United States)

    Greenhill, Simon J; Currie, Thomas E; Gray, Russell D

    2009-06-22

    Phylogenetic methods have recently been applied to studies of cultural evolution. However, it has been claimed that the large amount of horizontal transmission that sometimes occurs between cultural groups invalidates the use of these methods. Here, we use a natural model of linguistic evolution to simulate borrowing between languages. The results show that tree topologies constructed with Bayesian phylogenetic methods are robust to realistic levels of borrowing. Inferences about divergence dates are slightly less robust and show a tendency to underestimate dates. Our results demonstrate that realistic levels of reticulation between cultures do not invalidate a phylogenetic approach to cultural and linguistic evolution.

  11. Fluidization of a horizontally driven granular monolayer.

    Science.gov (United States)

    Heckel, Michael; Sack, Achim; Kollmer, Jonathan E; Pöschel, Thorsten

    2015-06-01

    We consider the transition of a horizontally vibrated monodisperse granular monolayer between its condensed state and its three-dimensional gaseous state as a function of the vibration parameters, amplitude, and frequency as well as particle number density. The transition is characterized by an abrupt change of the dynamical state which leaves its fingerprints in several measurable quantities including dissipation rate, sound emission, and a gap size which characterizes the sloshing motion of the material. The transition and its pronounced hysteresis is explained through the energy due to the collective motion of the particles relative to the container.

  12. Horizontal stability of a bouncing ball

    Science.gov (United States)

    McBennett, Brendan G.; Harris, Daniel M.

    2016-09-01

    We present an investigation of a partially elastic ball bouncing on a vertically vibrated concave parabolic surface in two dimensions. In particular, we demonstrate that simple vertical motion, wherein the ball bounces periodically at the parabola's vertex, is unstable to horizontal perturbations when the parabolic coefficient defining the surface shape exceeds a critical value. The result is a new periodic solution where the ball bounces laterally over the vertex. As the parabola is further steepened, this new solution also becomes unstable which gives rise to other complex periodic and chaotic bouncing states, all characterized by persistent lateral motion.

  13. Measures of Disassortativeness and their Application to Directly Transmitted Infections

    NARCIS (Netherlands)

    Farrington, C. P.; Whitaker, H. J.; Wallinga, J.; Manfredi, P.

    2009-01-01

    We propose a measure of disassortativeness to summarize contact patterns relevant to the transmission of directly transmitted infections. We discuss the properties of this measure, describe standardization relative to homogeneous mixing, and generalize it to multivariate contact structures. We explo

  14. Soil transmitted helminth infection among farmers in Ukwa West ...

    African Journals Online (AJOL)

    Soil transmitted helminth infection among farmers in Ukwa West Local Government Area, Abia State, south-east, Nigeria. ... Open Access DOWNLOAD FULL TEXT ... Collected data were analysed using descriptive and analytical tools. Results: ...

  15. Transmit TACAN Bearing Information with a Circular Array

    Directory of Open Access Journals (Sweden)

    W. Mark Dorsey

    2015-01-01

    Full Text Available Using TACAN and array fundamentals, we derive an architecture for transmitting TACAN bearing information from a circular array with time-varying weights. We evaluate performance for a simulated example array of Vivaldi elements.

  16. Transmittance spectroscopy and transmitted multispectral imaging to map covered paints

    Directory of Open Access Journals (Sweden)

    Antonino Cosentino

    2016-01-01

    Full Text Available Transmitted spectroscopy and transmitted multispectral imaging in the 400-900 nm range have been applied for the mapping and tentative identification of paints covered by a white preparation as in the case of a ground laid for reusing a canvas for another painting. These methods can be applied to polychrome works of art, as long as their support and new preparation are sufficiently translucent. This work presents the transmittance spectra acquired from a test board consisting of a prepared canvas with swatches of 54 pigments covered with titanium white and the multispectral images realized with transmitted light to map covered paints on a mock-up painting. It was observed that 18 out of 54 historical pigments provide characteristic transmittance spectra even underneath a titanium white preparation layer and that transmitted light multispectral imaging can map hidden paint layers.

  17. Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis

    DEFF Research Database (Denmark)

    Carlton, Jane M.; Hirt, Robert P.; Silva, Joana C.

    2007-01-01

    We describe the genome sequence of the protist Trichomonas vaginalis, a sexually transmitted human pathogen. Repeats and transposable elements comprise about two-thirds of the approximately 160-megabase genome, reflecting a recent massive expansion of genetic material. This expansion...

  18. Measures of Disassortativeness and their Application to Directly Transmitted Infections

    NARCIS (Netherlands)

    Farrington, C. P.; Whitaker, H. J.; Wallinga, J.; Manfredi, P.

    2009-01-01

    We propose a measure of disassortativeness to summarize contact patterns relevant to the transmission of directly transmitted infections. We discuss the properties of this measure, describe standardization relative to homogeneous mixing, and generalize it to multivariate contact structures. We explo

  19. Hedgehog(Hh)信号通路及P53在尖锐湿疣皮损中的表达及意义

    Institute of Scientific and Technical Information of China (English)

    朱文胜; 冯世军; 李萍

    2016-01-01

    目的:观察Hedgehog(Hh)信号通路及P53在尖锐湿疣皮损中的表达及意义,为临床提供参考。方法:选择我院收治的20例尖锐湿疣皮损患者(实验组)及20例健康体检者(对照组)作为观察对象,收治时间为2013年10月至2015年8月,采用免疫组化法对两组观察对象的Hedgehog(Hh)信号通路及P53表达情况进行检测,观察两组观察对象之间对比的Hedgehog(Hh)信号通路及P53阳性表达情况。结果:实验组20例尖锐湿疣皮损患者阳性表达情况明显高于对照组20例健康体检者(P<0.05),差异具有统计学意义。结论:P53在尖锐湿疣患者中皮损的表达上升说明Hedgehog(Hh)信号通路可能参与着尖锐湿疣的发生与发展过程中。

  20. Population dynamics of Rhipicephalus sanguineus (Latrielle, 1806) in Belo Horizonte, Minas Gerais state, Brazil.

    Science.gov (United States)

    Silveira, Júlia A G; Passos, Lygia M F; Ribeiro, Múcio F B

    2009-05-12

    Rhipicephalus sanguineus ticks are distributed throughout the world, especially in those areas in which dogs are in close contact with humans. R. sanguineus and fleas are regarded as the main ectoparasites infesting dogs in Brazil. Besides causing direct damage during the blood feeding process, this tick species can also transmit pathogens to dogs and humans. Despite its importance in Brazil, data regarding the seasonality of R. sanguineus are limited, especially with regard to natural infestations of dogs. The present study aimed to evaluate the seasonality of R. sanguineus on dogs living in Belo Horizonte, state of Minas Gerais. From August 2006 to July 2007, ticks were collected monthly from 12 adult dogs in nine houses, which were located in two districts in the north region of the city. In parallel, canine clients of a pet care department of the small animal veterinary clinic were examined for the presence of ticks before bathing and/or clipping. The climatic data recorded for Belo Horizonte during the experimental period were: mean temperature 18.6 degrees C; relative air humidity 56.5%; rainfall 37mm. The only species of ticks identified from all infested dogs was R. sanguineus, which was found in all its development stages. Among dogs living in houses, three tick population peaks were observed (August, February, and June), suggesting the occurrence of three generations per year in Belo Horizonte. A total of 7318 ticks were collected, of which 5422 were adult ticks and 1896 represented immature stages (744 larvae and 1152 nymphs). The monthly inspection of dogs living in houses demonstrated significantly higher parasitism during the dry season (pticks and the percentage of infested dogs in the dry season was higher (pticks was significantly higher (58.29%) than the percentage of infested female dogs (41.70%). This study of the dynamics of R. sanguineus infestations in Belo Horizonte will contribute to establishing appropriate measures to control tick

  1. How is Macro News Transmitted to Exchange Rates? (December 2003)

    OpenAIRE

    Martin D.D. Evans

    2005-01-01

    This paper tests whether macroeconomic news is transmitted to exchange rates via the transactions process and if so, what share occurs via transactions versus the traditional direct channel. We identify the link between order flow and macro news using a heteroskedasticity-based approach, a la Rigobon and Sack (2002). In both daily and intra-daily data, order flow varies considerably with macro news flow. At least half of the effect of macro news on exchange rates is transmitted via order flow.

  2. How is Macro News Transmitted to Exchange Rates?

    OpenAIRE

    Martin D.D. Evans; Lyons, Richard K.

    2003-01-01

    This paper tests whether macroeconomic news is transmitted to exchange rates via the transactions process and if so, what share occurs via transactions versus the traditional direct channel. We identify the link between order flow and macro news using a heteroskedasticity-based approach, a la Rigobon and Sack (2002). In both daily and intra-daily data, order flow varies considerably with macro news flow. At least half of the effect of macro news on exchange rates is transmitted via order flow.

  3. Risks of occupational expsoures to hand-transmitted vibration: VIBRISKS

    OpenAIRE

    Griffin, Michael J.; Lewis, Christopher H.; Bovenzi, Massimo; Lemerle, Pierre; Lundström, Ronnie

    2004-01-01

    VIBRISKS seeks to improve understanding of the risk of injury from hand-transmitted vibration and whole-body vibration by means of epidemiological studies supported by fundamental laboratory research. VIBRISKS is a consortium of six partners from six European countries (France, Germany, Italy, Sweden, The Netherlands, UK). The four-year research project, which commenced in 2003, involves three work packages devoted to hand-transmitted vibration and three work packages devoted to whole-body vi...

  4. Serological Strains of Tobacco Ringspot Virus Transmitted by Xiphinema americanum.

    Science.gov (United States)

    Rush, M C

    1970-07-01

    Five serological strains of tobacco ringspot virus isolated from naturally infected tobacco in North Carolina, and a strain isolated from watermelon in the Rio Grande Valley of Texas were transmitted from cucumber to cucumber by mass-screened and handpicked Xiphinerna americanum from North Carolina. The Eucharis mottle strain from Peru was not transmitted, indicating that a specific strain-vector relationship may exist between the geographically isolated strains from North and South America.

  5. Some Models for Epidemics of Vector-Transmitted Diseases

    OpenAIRE

    Brauer, Fred; Castillo-Chavez, Carlos; Mubayi, Anuj; Towers, Sherry

    2016-01-01

    Vector-transmitted diseases such as dengue fever and chikungunya have been spreading rapidly in many parts of the world. The Zika virus has been known since 1947 and invaded South America in 2013. It can be transmitted not only by (mosquito) vectors but also directly through sexual contact. Zika has developed into a serious global health problem because, while most cases are asymptomatic or very light, babies born to Zika - infected mothers may develop microcephaly and other very serious birt...

  6. Stratigraphic control and formation evaluation of horizontal wells with MWD

    Energy Technology Data Exchange (ETDEWEB)

    Hammons, L.R.B. (Eastman Teleco (United States)); Sellers, D.H.; Fisher, E.K. (Texaco Inc. (United States))

    1992-10-01

    Sandstone reservoirs in the Gulf of Mexico typically do not form horizontal planes, and a predetermined course for a horizontal well cannot ensure that the well path will remain within the producing interval throughout the horizontal section. Detecting approaching bed boundaries and fluid contacts early enough to make the changes necessary to keep the well path in the producing interval is an important technical issue during the planning and drilling of horizontal wells. This paper reports that the first two horizontal wells drilled in the Gulf of Mexico achieved this objective with measurement-while-drilling (MWD) resistivity measurements and with supporting computer modeling for bed boundary detection.

  7. Generation of large-scale winds in horizontally anisotropic convection

    CERN Document Server

    von Hardenberg, J; Provenzale, A; Spiegel, E A

    2015-01-01

    We simulate three-dimensional, horizontally periodic Rayleigh-B\\'enard convection between free-slip horizontal plates, rotating about a horizontal axis. When both the temperature difference between the plates and the rotation rate are sufficiently large, a strong horizontal wind is generated that is perpendicular to both the rotation vector and the gravity vector. The wind is turbulent, large-scale, and vertically sheared. Horizontal anisotropy, engendered here by rotation, appears necessary for such wind generation. Most of the kinetic energy of the flow resides in the wind, and the vertical turbulent heat flux is much lower on average than when there is no wind.

  8. A Flexible Phased-MIMO Array Antenna with Transmit Beamforming

    Directory of Open Access Journals (Sweden)

    Wen-Qin Wang

    2012-01-01

    Full Text Available Although phased-array antennas have been widely employed in modern radars, the requirements of many emerging applications call for new more advanced array antennas. This paper proposes a flexible phased-array multiple-input multiple-output (MIMO array antenna with transmit beamforming. This approach divides the transmit antenna array into multiple subarrays that are allowed to overlap each subarray coherently transmits a distinct waveform, which is orthogonal to the waveforms transmitted by other subarrays, at a distinct transmit frequency. That is, a small frequency increment is employed in each subarray. Each subarray forms a directional beam and all beams may be steered to different directions. The subarrays jointly offer flexible operating modes such as MIMO array which offers spatial diversity gain, phased-array which offers coherent directional gain and frequency diverse array which provides range-dependent beampattern. The system performance is examined by analyzing the transmit-receive beampatterns. The proposed approach is validated by extensive numerical simulation results.

  9. Horizontal Air Bearing Experiment Number 1

    Energy Technology Data Exchange (ETDEWEB)

    Clauson, T.L.

    1999-08-31

    The Horizontal Air Bearing Experiment No.1 is a series of tests intended to further the understanding of rotational dynamics. A simple experimental assembly is rotated using the Horizontal Air Bearing and allowed to spin freely as the internal rotational damping is measured. The low friction of the bearing effectively isolates the test assembly, allowing the internal damping of the test object to be evaluated. The experimental assembly is composed of an aluminum ball within a spherical cavity. A flanged pipe section and an auxiliary adapter plate secure the assembly to the Air Bearing interface plate. Three aluminum balls are interchanged to vary test parameters. The aluminum balls are free to move independently as the entire assembly rotates. The aluminum balls vary in diameter and/or surface finish. While the diameter and surface finish is varied, the space between the ball and socket is dry. To examine the effect of viscosity, the space is filled with a lubricant while the ball diameter and surface finish is held constant.

  10. The origin of extreme horizontal branch stars

    CERN Document Server

    Dorman, B; O'Connell, R W; Dorman, Ben; Rood, Robert T; O'Connell, Robert W

    1995-01-01

    Strong mass loss on the red giant branch (RGB) can result in the formation of extreme horizontal branch (EHB) stars. The EHB stars spend most of their He core and shell burning phase at high temperatures and produce copious ultraviolet flux. They have very small hydrogen envelopes and occupy a small range in mass. We have computed evolutionary RGB models with mass loss for stars with a range of metallicities at initial masses < 1.1 Msun corresponding to populations ages between 12.5 and 14.5 Gyr. We used the Reimers formula to characterize mass loss, but investigated a larger range of the mass loss efficiency parameter, eta, than is common. To understand how the number of EHB stars varies with metallicity in a stellar population we considered how the zero-age horizontal branch (ZAHB) is populated. The range in eta producing EHB stars is comparable to that producing `mid-HB' stars. Somewhat surprisingly, neither the range nor magnitude of eta producing EHB stars varies much metallicity. In contrast, the ran...

  11. Applying GPS to check horizontal control quality

    Directory of Open Access Journals (Sweden)

    Jakub Vincent

    2004-03-01

    Full Text Available GPS technologies can also be used for check quality in available horizontal point set with coordinates CJ of the frame S-JTSK. When survey and setting-out tasks should be performed in certain area, one can found in it allways some points of the fundamental and detail state controls. To use these points for some actual aims, it is necessary to investigate their compatibility (among the point mark positions and the point coordinate of control points. This can be done using GPS surveying that may be at the same time employed to determine the new point in the relevant area.Principle of quality investigatingf an existing control is founded on determination of point coordinates CJt from GPS measurements. Then, based on discrepancies among the "official" netpoint coordinates CJ and coordinates CJt "given by GPS", it can be estimated the degree and the real compatibility dislocations in the network structure of the existing points.Realisation procedure for the introduced investigation is demonstrated on GPS checking (by SOKKIA STRATUS receivers horizontal control for reconstruction of a railway bridge on river Bodrog in East Slovakia.It can be shown from the results in Table 3, that points P3 and P7 are useless due to their incompatibility (inconsistency in the inspected point set. For other 7 points (Table 7 the average measure of incompatibility reads 9.8 mm that make possible applying these points for precise setting-out

  12. Pattern selection in a horizontally vibrated container

    Energy Technology Data Exchange (ETDEWEB)

    Porter, J; Tinao, I; Laveron-Simavilla, A; Lopez, C A, E-mail: jeff.porter@upm.es [E.T.S.I. Aeronauticos, Universidad Politecnica de Madrid, Plaza Cardenal Cisneros 3, 28040 Madrid (Spain)

    2012-10-15

    We present results of an experimental and numerical investigation of the patterns realized by surface waves within an open rectangular container subjected to horizontal vibrations at frequencies of 40-100 Hz. The first instability exhibited by the primary harmonic wave field is subharmonic, and may be identified with the cross-wave instability often seen in wave tank experiments. We show that, contrary to common theoretical and experimental assumptions, and despite their name, these subharmonic waves are not oriented crosswise, but at an intermediate angle with respect to the axis of vibration. Hence, the pattern selection problem for horizontally forced Faraday waves is more complex than has previously been assumed. We establish the robustness of this obliquely oriented surface wave pattern by varying the forcing frequency and amplitude, the fluid viscosity, the fluid depth, and the boundary conditions. Previous work on cross-waves is reviewed and discussed in relation to the current results. Finally, numerical simulations using a reduced model with an appropriate forcing term are used to support the generality of the experimental observations. (paper)

  13. The innate defense regulator peptides IDR-HH2, IDR-1002, and IDR-1018 modulate human neutrophil functions.

    Science.gov (United States)

    Niyonsaba, François; Madera, Laurence; Afacan, Nicole; Okumura, Ko; Ogawa, Hideoki; Hancock, Robert E W

    2013-07-01

    Although HDPs were originally hypothesized to act as antimicrobial agents, they also have been shown to broadly modulate the immune response through the activation of different cell types. We recently developed a series of novel, synthetic peptides, termed IDRs, which are conceptually based on a natural HDP, bovine bactenecin. We showed that IDR-1 and IDR-1002 protect the host against bacterial infections through the induction of chemokines. The objective of this study was to investigate the effects of the IDRs on various functions of human neutrophils. Here, we demonstrated that IDR-HH2, IDR-1002, and IDR-1018 modulated the expression of neutrophil adhesion and activation markers. Moreover, these IDRs enhanced neutrophil adhesion to endothelial cells in a β₂ integrin-dependent manner and induced neutrophil migration and chemokine production. The IDR peptides also increased the release of the neutrophil-generated HDPs (antimicrobial), human α-defensins, and LL-37 and augmented neutrophil-mediated killing of Escherichia coli. Notably, the IDRs significantly suppressed LPS-mediated neutrophil degranulation, the release of ROS, and the production of the inflammatory cytokines TNF-α and IL-10, consistent with their ability to dampen inflammation. As evidenced by the inhibitory effects of MAPK-specific inhibitors, IDRs activated the MAPK pathway that was required for chemokine production. In conclusion, our study provides novel evidence regarding the contribution of the IDR peptides to the innate immune response through the modulation of neutrophil functions. The results described here may aid in the development of IDRs as novel, anti-infective and immunomodulatory agents.

  14. Current Status of Soil-transmitted Nematode Infection in China

    Institute of Scientific and Technical Information of China (English)

    YING-DAN CHEN; LIN-HUA TANG; LONG-QI XU

    2008-01-01

    Objective To Carry out national surveys for ascertaining the current status and trends of soil-transmitted nematode infections in China,providing scientific basis for forther developing control strategies.Methods In 1988-1992(hereinafter abbreriated as "survey in 1990"),a stratified cluster random sampling method was used in the survey.In 2001-2004(hereinafter abbreriated as "survey in 2003"),in order to compare with the survey in 1990,two-characteristic stratified cluster random sampling method was used and 687 investigation spots were sampled from the 2848 spots selected in the survey in 1990.Kato-Katz thick smear method was used to examine the eggs of soil-transmitted nematodes in fecal samples. Results The prevalence rates were 53.6% and 19.6% for soil-transmitted nematodes,14.6%and 6.120% for hookworms,44.6% and 12.7% for Ascaris lumbricoides,17.4% and 4.630% for Trichuris trichiura in survey 1990 and survey 2003,respectively.The prevalence rates of soil-transmitted nematodes were higher in 13 provinces than the average level in China in the survey in 1990.and higher in 8 provinces than the average level in the survey in 2003.The prevalence of hookworms,Ascaris lumbricoides,Trichurls trichiura and the overall prevalence of soft-transmitted nematodes were higher in females than in males.It is estimated from the results of survey in 2003 that the number of persons with soil-transmitted nematode infections in the country is about 129 million,less than that in the survey in 1990. Conclusion The prevalence of soil-transmitted nematodes has declined considerably but is still relatively high in some provinces and autonomous regions.Control activities and socioeconomic development may have contributed to the decreased prevalence.

  15. NUMERICAL DETERMINATION OF HORIZONTAL SETTLERS PERFORMANCE

    Directory of Open Access Journals (Sweden)

    M. M. Biliaiev

    2015-08-01

    Full Text Available Purpose.Horizontal settlers are one of the most important elements in the technological scheme of water purification. Their use is associated with the possibility to pass a sufficiently large volume of water. The important task at the stage of their designing is evaluating of their effectiveness. Calculation of the efficiency of the settler can be made by mathematical modeling. Empirical, analytical models and techniques that are currently used to solve the problem, do not allow to take into account the shape of the sump and various design features that significantly affects the loyalty to a decision on the choice of the size of the settling tank and its design features. The use of analytical models is limited only to one-dimensional solutions, does not allow accounting for nonuniform velocity field of the flow in the settler. The use of advanced turbulence models for the calculation of the hydrodynamics in the settler complex forms now requires very powerful computers. In addition, the calculation of one variant of the settler may last for dozens of hours. The aim of the paper is to build a numerical model to evaluate the effectiveness of horizontal settling tank modified design. Methodology. Numerical models are based on: 1 equation of potential flow; 2 equation of inviscid fluid vortex flow; 3 equation of viscous fluid dynamics; 4 mass transfer equation. For numerical simulation the finite difference schemes are used. The numerical calculation is carried out on a rectangular grid. For the formation of the computational domain markers are used. Findings.The models allow calculating the clarification process in the settler with different form and different configuration of baffles. Originality. A new approach to investigate the mass transfer process in horizontal settler was proposed. This approach is based on the developed CFD models. Three fluid dynamics models were used for the numerical investigation of flows and waste waters purification

  16. Horizon-T Experiment Calibrations - Cables

    CERN Document Server

    Beznosko, D; Iakovlev, A; Makhataeva, Z; Vildanova, M I; Yelshibekov, K; Zhukov, V V

    2016-01-01

    An innovative detector system called Horizon-T is constructed to study Extensive Air Showers (EAS) in the energy range above 1016 eV coming from a wide range of zenith angles (0o - 85o). The system is located at Tien Shan high-altitude Science Station of Lebedev Physical Institute of the Russian Academy of Sciences at approximately 3340 meters above the sea level. The detector consists of eight charged particle detection points separated by the distance up to one kilometer as well as optical detector to view the Vavilov-\\v{C}erenkov light from the EAS. Each detector connects to the Data Acquisition system via cables. The calibration of the time delay for each cable and the signal attenuation is provided in this article.

  17. Modelling the horizontal steam generator with APROS

    Energy Technology Data Exchange (ETDEWEB)

    Ylijoki, J. [VTT Energy, Espoo (Finland); Palsinajaervi, C.; Porkholm, K. [IVO International Ltd, Vantaa (Finland)

    1995-12-31

    In this paper the capability of the five- and six-equation models of the simulation code APROS to simulate the behaviour of the horizontal steam generator is discussed. Different nodalizations are used in the modelling and the results of the stationary state runs are compared. Exactly the same nodalizations have been created for the five- and six-equation models. The main simulation results studied in this paper are void fraction and mass flow distributions in the secondary side of the steam generator. It was found that quite a large number of simulation volumes is required to simulate the distributions with a reasonable accuracy. The simulation results of the different models are presented and their validity is discussed. (orig.). 4 refs.

  18. Horizontal gene exchange in environmental microbiota

    Directory of Open Access Journals (Sweden)

    Rustam I Aminov

    2011-07-01

    Full Text Available Horizontal gene transfer (HGT plays an important role in the evolution of life on the Earth. This view is supported by numerous occasions of HGT that are recorded in the genomes of all three domains of living organisms. HGT-mediated rapid evolution is especially noticeable among the Bacteria, which demonstrate formidable adaptability in the face of recent environmental changes imposed by human activities, such as the use of antibiotics, industrial contamination, and intensive agriculture. At the heart of the HGT-driven bacterial evolution and adaptation are highly sophisticated natural genetic engineering tools in the form of a variety of mobile genetic elements (MGEs. The main aim of this review is to give a brief account of the occurrence and diversity of MGEs in natural ecosystems and of the environmental factors that may affect MGE-mediated HGT.

  19. Multimodal Distributions along the Horizontal Branch

    CERN Document Server

    Ferraro, F R; Pecci, F F; Dorman, B; Rood, R T; Ferraro, Francesco R.; Paltrinieri, Barbara; Pecci, Flavio Fusi; Dorman, Ben; Rood, Robert T.

    1997-01-01

    We report on HST/WFPC2 U,V and far-ultraviolet observations of two Galactic Globular Clusters (GGCs), NGC 6205 = M13 and NGC 6093 = M80. Both of these clusters have horizontal-branch (HB) tails that extend to the helium-burning main sequence, with the hottest stars reaching theoretical effective temperatures above 35,000 K. In both clusters, groups of stars are found to be separated by narrow gaps along the blue HB sequence. These gaps appear at similar locations in the color-magnitude diagrams of the two clusters. While stochastic effects may give rise to variations in the color distribution along the HB, the coincidence of gaps in different clusters effectively rules this out as the primary cause. The comparison among the clusters strongly suggests that there are separate physical processes operating during the earlier red-giant phase of evolution to produce mass loss.

  20. Horizontal stresses below two agricultural vehicles

    DEFF Research Database (Denmark)

    Lamande, Mathieu André Maurice; Munkholm, Lars Juhl; Nielsen, Janne Aalborg

    , while shear stress larger than soil strength may affect intensity soil properties (i.e. air permeability) by soil deformation not necessarily associated with compaction. In previous experiments in field conditions, isotropic compaction was observed below the center of tires, while shearing took place...... below the edge of tires. Stress distribution at the tire/soil contact is not uniform. Dimensions and inflation pressure are key factors for the ability of agricultural tires to distribute the wheel load. Our hypothesis was that the risk of shearing increases with the tire inflation pressure...... and the number of wheels. We measured horizontal stress at two depths (0.3 and 0.5 m) below tires of two slurry spreaders: one self-propelled machine equipped with wide tires (1.050 m) and low inflation pressure (150 kPa) but carrying a high wheel load (120 kN), and one tractor towing a three-axle slurry...

  1. Passive magnetic bearing for a horizontal shaft

    Energy Technology Data Exchange (ETDEWEB)

    Post, Richard F.

    2003-12-02

    A passive magnetic bearing is composed of a levitation element and a restorative element. The levitation element is composed of a pair of stationary arcuate ferromagnetic segments located within an annular radial-field magnet array. The magnet array is attached to the inner circumference of a hollow shaft end. An attractive force between the arcuate segments and the magnet array acts vertically to levitate the shaft, and also in a horizontal transverse direction to center the shaft. The restorative element is comprised of an annular Halbach array of magnets and a stationary annular circuit array located within the Halbach array. The Halbach array is attached to the inner circumference of the hollow shaft end. A repulsive force between the Halbach array and the circuit array increases inversely to the radial space between them, and thus acts to restore the shaft to its equilibrium axis of rotation when it is displaced therefrom.

  2. Numerical Investigation on Submerged Horizontal Plate

    Institute of Scientific and Technical Information of China (English)

    康海贵; 王科

    2001-01-01

    Hydrodynamic characters on a horizontal, thin, rigid plate located beneath the free surface are numerically investigated. Assuming a linear, time-harmonic potential flow and utilizing Green identity, the governing Laplace equation can be simplified into Fredholm integral equation ofthe second kind. Supposing linear-order discontinuous elements along intersecting vertical boundaries, and by use of the boundary element method, numerical solution about source strength distribution on the plate can be changed into a series of algebraic equations. The 3D Green function is introduced to set up the integral equations, and the GMRES solver is performed for solving the large dense linear system of equations. The added-mass, damping force and exciting force are evaluated directly from the equations. It is found that the added-mass coefficient becomes negative for a range of frequencies when the plate is sufficiently close to the free surface.

  3. Horizontal Gene Transfer, Dispersal and Haloarchaeal Speciation

    Directory of Open Access Journals (Sweden)

    R. Thane Papke

    2015-05-01

    Full Text Available The Halobacteria are a well-studied archaeal class and numerous investigations are showing how their diversity is distributed amongst genomes and geographic locations. Evidence indicates that recombination between species continuously facilitates the arrival of new genes, and within species, it is frequent enough to spread acquired genes amongst all individuals in the population. To create permanent independent diversity and generate new species, barriers to recombination are probably required. The data support an interpretation that rates of evolution (e.g., horizontal gene transfer and mutation are faster at creating geographically localized variation than dispersal and invasion are at homogenizing genetic differences between locations. Therefore, we suggest that recurrent episodes of dispersal followed by variable periods of endemism break the homogenizing forces of intrapopulation recombination and that this process might be the principal stimulus leading to divergence and speciation in Halobacteria.

  4. Horizontal Gene Transfer, Dispersal and Haloarchaeal Speciation

    Science.gov (United States)

    Papke, R. Thane; Corral, Paulina; Ram-Mohan, Nikhil; de la Haba, Rafael R.; Sánchez-Porro, Cristina; Makkay, Andrea; Ventosa, Antonio

    2015-01-01

    The Halobacteria are a well-studied archaeal class and numerous investigations are showing how their diversity is distributed amongst genomes and geographic locations. Evidence indicates that recombination between species continuously facilitates the arrival of new genes, and within species, it is frequent enough to spread acquired genes amongst all individuals in the population. To create permanent independent diversity and generate new species, barriers to recombination are probably required. The data support an interpretation that rates of evolution (e.g., horizontal gene transfer and mutation) are faster at creating geographically localized variation than dispersal and invasion are at homogenizing genetic differences between locations. Therefore, we suggest that recurrent episodes of dispersal followed by variable periods of endemism break the homogenizing forces of intrapopulation recombination and that this process might be the principal stimulus leading to divergence and speciation in Halobacteria. PMID:25997110

  5. Horizontal shear wave scattering from a nonwelded interface observed by magnetic resonance elastography

    Science.gov (United States)

    Papazoglou, S.; Hamhaber, U.; Braun, J.; Sack, I.

    2007-02-01

    A method based on magnetic resonance elastography is presented that allows measuring the weldedness of interfaces between soft tissue layers. The technique exploits the dependence of shear wave scattering at elastic interfaces on the frequency of vibration. Experiments were performed on gel phantoms including differently welded interfaces. Plane wave excitation parallel to the planar interface with corresponding motion sensitization enabled the observation of only shear-horizontal (SH) wave scattering. Spatio-temporal filtering was applied to calculate scattering coefficients from the amplitudes of the incident, transmitted and reflected SH-waves in the vicinity of the interface. The results illustrate that acoustic wave scattering in soft tissues is largely dependent on the connectivity of interfaces, which is potentially interesting for imaging tissue mechanics in medicine and biology.

  6. novos elementos e horizontes para o cuidado

    Directory of Open Access Journals (Sweden)

    Rosa Lúcia Rocha Ribeiro

    2007-01-01

    Full Text Available La condición crónica ha sido un tema de importancia extrema para la reflexión del proceso de vivir humano. En el artículo se presenta la síntesis de una investigación realizada con la finalidad de comprender cómo los niños con Síndrome Nefrótico son cuidados, buscando identificar nuevos elementos y horizontes para reconstruir el cuidado de enfermería, teniendo como foco la familia. Para la presente investigación, se realizó un estudio cualitativo que utilizó como referente teórico metodológico, la hermenéutica basada en Gadamer y Ricouer. De la investigación realizada en 2004, participaron 42 personas pertenecientes a las familias de niños y adolescentes con Síndrome Nefrótico, usuarias del Servicio de Nefrología Pediátrica del Hospital Universitario Júlio Müller, en Cuiabá, Brasil. En la discusión son presentadas: una síntesis de las familias, sus proyectos, personajes y contexto; la trayectoria de la enfermedad del niño en la familia, y el cuidado del niño nefrótico en la familia. Se muestran también los horizontes de los cuidadores, familiares y profesionales de salud, y el cuidado posible a partir de los arreglos de la familia. Se puede concluir que el diálogo es la primera condición para la comprensión y también para el cuidado.

  7. Influence of sexually transmitted infections in a horse breeding

    Directory of Open Access Journals (Sweden)

    Kosec Marjan

    2015-01-01

    Full Text Available The most frequent problems in horses reproduction are generally divided into those of infectious and non infectious etiology. Common causes of infectious diseases are usual­ly viruses and bacteria, and less frequently protozoa, mykoplasma and fungi. In this work there are presented the most important fact about sexually transmitted diseases, their clinical picture, risk factors, preventive measures as well as measures to prevent and eradicate the diseases. The biggest risk factor for sexually transmitted diseases in horses are breeding stallions, both in natural mating and in artificial insemination. Therefore, in order to prevent genital infections in horses, it is essential that the stallions used for breeding are healthy (non-infected. That can be determined with certainty only if the stallions are examined (tested just before the breeding season on most frequent sexually transmitted diseases (CEM,EAV. It is well known that in most cases the clinical picture of sexually transmitted diseses is not manifested on genitals. As well, variations in clinical picture can be expected also in mares, depending on the stage of the disease and its etiology. Harms arising from sexually transmitted diseases can be divided into direct and indirect. Direct damage occurs in the form of endometritis, miscarriage, stillbirths and births of weak foals, and indirect in restricting the traffic of infected and suspicios animals, isolation of the infected ones as well as medical treatment and interrupting mating.

  8. Decreasing Prevalence of Transfusion Transmitted Infection in Indian Scenario

    Directory of Open Access Journals (Sweden)

    Tulika Chandra

    2014-01-01

    Full Text Available Transfusion transmitted infections are major problem associated with blood transfusion. Accurate estimates of risk of TTIs are essential for monitoring the safety of blood supply and evaluating the efficacy of currently employed screening procedures. The present study was carried out to assess the percentage of voluntary donors and replacement donors and to find out prevalence and changing trends of various TTIs blood donors in recent years. A study was carried out on blood units of voluntary and replacement donors which were collected from January 2008 to December 2012. On screening of 180,371 replacement units, seropositivity of transfusion transmitted disease in replacement donors was 0.15% in HIV, 1.67% in hepatitis B surface antigen, 0.49% in hepatitis C virus, 0.01% in VDRL, and 0.009% in malaria. Of 11,977 voluntary units, seropositivity of transfusion transmitted disease in voluntary donors was 0.08% in HIV, 0.24% in hepatitis B surface antigen, 0.001% in hepatitis C virus, 0.008% in VDRL (sexually transmitted disease, and 0.01% in malaria. From results it has been concluded that prevalence of transfusion transmitted infection (HIV, HBV, HCV, VDRL, and malaria was more in replacement donors in comparison to voluntary donors. Extensive donor selection and screening procedures will help in improving the blood safety.

  9. Decreasing prevalence of transfusion transmitted infection in Indian scenario.

    Science.gov (United States)

    Chandra, Tulika; Rizvi, S Nishat Fatima; Agarwal, Devisha

    2014-01-01

    Transfusion transmitted infections are major problem associated with blood transfusion. Accurate estimates of risk of TTIs are essential for monitoring the safety of blood supply and evaluating the efficacy of currently employed screening procedures. The present study was carried out to assess the percentage of voluntary donors and replacement donors and to find out prevalence and changing trends of various TTIs blood donors in recent years. A study was carried out on blood units of voluntary and replacement donors which were collected from January 2008 to December 2012. On screening of 180,371 replacement units, seropositivity of transfusion transmitted disease in replacement donors was 0.15% in HIV, 1.67% in hepatitis B surface antigen, 0.49% in hepatitis C virus, 0.01% in VDRL, and 0.009% in malaria. Of 11,977 voluntary units, seropositivity of transfusion transmitted disease in voluntary donors was 0.08% in HIV, 0.24% in hepatitis B surface antigen, 0.001% in hepatitis C virus, 0.008% in VDRL (sexually transmitted disease), and 0.01% in malaria. From results it has been concluded that prevalence of transfusion transmitted infection (HIV, HBV, HCV, VDRL, and malaria) was more in replacement donors in comparison to voluntary donors. Extensive donor selection and screening procedures will help in improving the blood safety.

  10. Bilateral horizontal Vogt’s striae in keratoconus

    Directory of Open Access Journals (Sweden)

    Inci Ulu Güngör

    2008-10-01

    Full Text Available Inci Ulu Güngör, Ümit Beden, Baris SönmezOndokuz Mayis University, School of Medicine, Department of Ophthalmology, Samsun, TurkeyPurpose: To report a keratoconus case with bilateral horizontal Vogt’s striae.Method: The clinical findings of the patient and the development of the direction of striae are discussed.Results: Vogt’s striae, defined as vertical stress lines, are rarely horizontal. One patient with unilateral horizontal stress lines on his left eye has been reported in the literature. Our patient has horizontal Vogt’s striae in both eyes.Conclusion: Horizontal Vogt’s striae may be seen in keratoconus as a rare slit-lamp biomicroscopic finding.Keywords: keratoconus, Vogt’s striae, horizontal stress lines

  11. The Control of Transmitted Power in an Active Isolation System

    DEFF Research Database (Denmark)

    Elliott, S.J.; Gardonio, P.; Pinnington, R.J.

    1997-01-01

    The isolation of vibration through a system with multiple active mounts is discussed, in which each of the mounts can transmit vibration in several degrees of freedom. Theoretical models of the various parts of this system have been developed which include a flexible receiving structure and distr...... of such an active vibration control system are also discussed.......The isolation of vibration through a system with multiple active mounts is discussed, in which each of the mounts can transmit vibration in several degrees of freedom. Theoretical models of the various parts of this system have been developed which include a flexible receiving structure...... and distributed active mounts, and these models can be connected together to produce an overall theoretical description of a realistic active isolation system. Total transmitted power has been found to be an excellent criterion to quantify the effect of various control strategies in this model in which...

  12. Potential for New York mosquitoes to transmit West Nile virus.

    Science.gov (United States)

    Turell, M J; O'Guinn, M; Oliver, J

    2000-03-01

    We evaluated the potential for several North American mosquito species to transmit the newly introduced West Nile (WN) virus. Mosquitoes collected in the New York City Metropolitan Area during the recent (1999) WN outbreak were allowed to feed on chickens infected with WN virus isolated from a crow that had died during this outbreak. These mosquitoes were tested approximately 2 weeks later to determine infection, dissemination, and transmission rates. Culex pipiens mosquitoes were highly susceptible to infection, and nearly all individuals with a disseminated infection did transmit WN virus by bite. In contrast, Aedes vexans were only moderately susceptible to oral infection; however, those individuals inoculated with WN virus did transmit virus by bite.

  13. Infections Transmitted By the Transfusion of Blood and Blood Products

    Directory of Open Access Journals (Sweden)

    Tekin A.

    2011-05-01

    Full Text Available Especially viral hepatitis viruses and human immunodeficiency virus(HIV which were transmitted by the transfusion of blood and blood products have been an important public health problem for a long time on the world. Transfusion of blood and blood products is an ideal and an easiest and a simplest route for transmission of infectious diseases. It is known that many infectious agents, either bacterial, viral, parasitic and fungal agents may be transmitted by the transfusion of blood and blood products. In present study, we reviewed infection diseases that transmitted by the transfusion of blood and blood products.Additionally, we were aimed to emphasize a rare but a very important complication of transfusion of blood and blood products.

  14. System for transmitting and receiving multi-polarized signals

    DEFF Research Database (Denmark)

    2016-01-01

    The present disclosure relates to: an optical receiver, configured to receive at least three multiplexed, differently polarized, optically transmitted signals, each signal associated with a predefined state of polarization, said receiver comprising a multi- polarization analyzer for obtaining...... an analyzed signal for each of said polarized signals, wherein at least one of said analyzed signals comprises data in the full Stokes space; an optical transmitter, configured to transmit at least three multiplexed, differently polarized, optically transmitted signals, wherein at least one of said polarized...... signals comprises data in the full Stokes space; a system configured to communicate optically over a communication link, comprising: an optical transmitter, configured to generate and multiplex at least three independent data signals having different states of polarization into a multiplexed signal...

  15. Transmit antenna selection based on shadowing side information

    KAUST Repository

    Yilmaz, Ferkan

    2011-05-01

    In this paper, we propose a new transmit antenna selection scheme based on shadowing side information. In the proposed scheme, single transmit antenna which has the highest shadowing coefficient is selected. By the proposed technique, usage of the feedback channel and channel estimation complexity at the receiver can be reduced. We consider independent but not identically distributed Generalized-K composite fading model, which is a general composite fading & shadowing channel model for wireless environments. Exact closed-form outage probability, moment generating function and symbol error probability expressions are derived. In addition, theoretical performance results are validated by Monte Carlo simulations. © 2011 IEEE.

  16. Integrated differential high-voltage transmitting circuit for CMUTs

    DEFF Research Database (Denmark)

    Llimos Muntal, Pere; Larsen, Dennis Øland; Farch, Kjartan

    2015-01-01

    In this paper an integrated differential high-voltage transmitting circuit for capacitive micromachined ultrasonic transducers (CMUTs) used in portable ultrasound scanners is designed and implemented in a 0.35 μm high-voltage process. Measurements are performed on the integrated circuit in order...... to assess its performance. The circuit generates pulses at differential voltage levels of 60V, 80V and 100 V, a frequency up to 5MHz and a measured driving strength of 1.75 V/ns with the CMUT connected. The total on-chip area occupied by the transmitting circuit is 0.18 mm2 and the power consumption...

  17. Reflecting and transmitting effect of a planar unidirectionally conducting screen

    Institute of Scientific and Technical Information of China (English)

    E Peng; JIANG Bin-hao

    2009-01-01

    The reflecting and transmitting effects of a planar unidirectionally conducting screen are analyzed based on the accurate closed-form expression for electric field of an arbitrarily oriented electric dipole. For a dipole oriented along the wire elements of the screen, the screen acts as a perfectly electrically conducting plane.For a dipole perpendicular to the wire elements, the fields reflected by the screen can be interpreted as the contribution of an image dipole and image transmission-line current source, while the transmitted field is arisen from image transmission-line source. The expressions of related surface waves are derived and can be compared with previous results.

  18. Cutaneous diphtheria masquerading as a sexually transmitted disease

    Directory of Open Access Journals (Sweden)

    Vetrichevvel T

    2008-01-01

    Full Text Available A 41 year-old, sexually promiscuous, married male, an agricultural laborer by occupation, presented to our sexually transmitted diseases (STD clinic with multiple ulcers over the scrotum and genitalia of 20 days′ duration. Bacterial culture from swabs taken from the genital ulcer, grew organisms morphologically and biochemically characteristic of Corynaebacterium diphtheriae. He made a complete and uneventful recovery after two weeks of therapy with antidiphtheria serum and crystalline penicillin. This case brings into light this hitherto unreported presentation of wound diphtheria mimicking a sexually transmitted genital ulcer disease and thus, underlines the importance of considering diphtheria as differential in atypical, long-standing genital ulcers.

  19. Microwave power transmitting phased array antenna research project

    Science.gov (United States)

    Dickinson, R. M.

    1978-01-01

    An initial design study and the development results of an S band RF power transmitting phased array antenna experiment system are presented. The array was to be designed, constructed and instrumented to permit wireless power transmission technology evaluation measurements. The planned measurements were to provide data relative to the achievable performance in the state of the art of flexible surface, retrodirective arrays, as a step in technically evaluating the satellite power system concept for importing to earth, via microwave beams, the nearly continuous solar power available in geosynchronous orbit. Details of the microwave power transmitting phased array design, instrumentation approaches, system block diagrams, and measured component and breadboard characteristics achieved are presented.

  20. ALMA Cycle 1 Observations of the HH46/47 Molecular Outflow: Structure, Entrainment, and Core Impact

    Science.gov (United States)

    Zhang, Yichen; Arce, Héctor G.; Mardones, Diego; Cabrit, Sylvie; Dunham, Michael M.; Garay, Guido; Noriega-Crespo, Alberto; Offner, Stella S. R.; Raga, Alejandro C.; Corder, Stuartt A.

    2016-12-01

    We present Atacama Large Millimeter/sub-millimeter Array Cycle 1 observations of the HH 46/47 molecular outflow using combined 12 m array and Atacama Compact Array observations. The improved angular resolution and sensitivity of our multi-line maps reveal structures that help us study the entrainment process in much more detail and allow us to obtain more precise estimates of outflow properties than in previous observations. We use {}13{{CO}} (1-0) and {{{C}}}18{{O}} (1-0) emission to correct for the {}12{{CO}} (1-0) optical depth to accurately estimate the outflow mass, momentum, and kinetic energy. This correction increases the estimates of the mass, momentum, and kinetic energy by factors of about 9, 5, and 2, respectively, with respect to estimates assuming optically thin emission. The new {}13{{CO}} and {{{C}}}18{{O}} data also allow us to trace denser and slower outflow material than that traced by the {}12{{CO}} maps, and they reveal an outflow cavity wall at very low velocities (as low as 0.2 {\\text{km s}}-1 with respect to the core’s central velocity). Adding the slower material traced only by {}13{{CO}} and {{{C}}}18{{O}}, there is another factor of three increase in the mass estimate and 50% increase in the momentum estimate. The estimated outflow properties indicate that the outflow is capable of dispersing the parent core within the typical lifetime of the embedded phase of a low-mass protostar and that it is responsible for a core-to-star efficiency of 1/4 to 1/3. We find that the outflow cavity wall is composed of multiple shells associated with a series of jet bow-shock events. Within about 3000 au of the protostar the {}13{{CO}} and {{{C}}}18{{O}} emission trace a circumstellar envelope with both rotation and infall motions, which we compare with a simple analytic model. The CS (2-1) emission reveals tentative evidence of a slowly moving rotating outflow, which we suggest is entrained not only poloidally but also toroidally by a disk wind that

  1. Characterizing local variability in long‐period horizontal tilt noise

    Science.gov (United States)

    Rohde, M.D.; Ringler, Adam; Hutt, Charles R.; Wilson, David; Holland, Austin; Sandoval, L.D; Storm, Tyler

    2017-01-01

    Horizontal seismic data are dominated by atmospherically induced tilt noise at long periods (i.e., 30 s and greater). Tilt noise limits our ability to use horizontal data for sensitive seismological studies such as observing free earth modes. To better understand the local spatial variability of long‐period horizontal noise, we observe horizontal noise during quiet time periods in the Albuquerque Seismological Laboratory (ASL) underground vault using four small‐aperture array configurations. Each array comprises eight Streckeisen STS‐2 broadband seismometers. We analyze the spectral content of the data using power spectral density and magnitude‐squared coherence (γ2‐coherence). Our results show a high degree of spatial variability and frequency dependence in the long‐period horizontal wavefield. The variable nature of long‐period horizontal noise in the ASL vault suggests that it might be highly local in nature and not easily characterized by simple physical models when overall noise levels are low, making it difficult to identify locations in the vault with lower horizontal noise. This variability could be limiting our ability to apply coherence analysis for estimating horizontal sensor self‐noise and could also complicate various indirect methods for removing long‐period horizontal noise (e.g., collocated rotational sensor or microbarograph).

  2. Cuttings Transport Models and Experimental Visualization of Underbalanced Horizontal Drilling

    Directory of Open Access Journals (Sweden)

    Na Wei

    2013-01-01

    Full Text Available Aerated underbalanced horizontal drilling technology has become the focus of the drilling industry at home and abroad, and one of the engineering core issues is the horizontal borehole cleaning. Therefore, calculating the minimum injection volume of gas and liquid accurately is essential for the construction in aerated underbalanced horizontal drilling. This paper establishes a physical model of carrying cuttings and borehole cleaning in wellbore of horizontal well and a critical transport mathematical model according to gas-liquid-solid flow mechanism and large plane dunes particle transport theory.

  3. 45 Km Horizontal Path Optical Link Experiment

    Science.gov (United States)

    Biswas, A.; Ceniceros, J.; Novak, M.; Jeganathan, M.; Portillo, A.; Erickson, D.; Depew, J.; Sanii, B.; Lesh, J. R.

    2000-01-01

    Mountain-top to mountain-top optical link experiments have been initiated at JPL, in order to perform a systems level evaluation of optical communications. Progress made so far is reported. ne NASA, JPL developed optical communications demonstrator (OCD) is used to transmit a laser signal from Strawberry Peak (SP), located in the San Bernadino mountains of California. This laser beam is received by a 0.6 m aperture telescope at JPL's Table Mountain Facility (TMF), located in Wrightwood, California. The optical link is bi-directional with the TMF telescope transmitting a continuous 4-wave (cw) 780 run beacon and the OCD sending back a 840 nm, 100 - 500 Mbps pseudo noise (PN) modulated, laser beam. The optical link path is at an average altitude of 2 km above sea level, covers a range of 46.8 km and provides an atmospheric channel equivalent to approx. 4 air masses. Average received power measured at either end fall well within the uncertainties predicted by link analysis. The reduction in normalized intensity variance (sigma(sup 2, sub I)) for the 4-beam beacon, compared to each individual beam, at SP, was from approx. 0.68 to 0.22. With some allowance for intra-beam mis-alignment, this is consistent with incoherent averaging. The sigma(sup2, sub I) measured at TMF approx. 0.43 +/- 0.22 exceeded the expected aperture averaged value of less than 0.1, probably because of beam wander. The focused spot sizes of approx. 162 +/- 6 microns at the TMF Coude and approx. 64 +/- 3 microns on the OCD compare to the predicted size range of 52 - 172 microns and 57 - 93 microns, respectively. This is consistent with 4 - 5 arcsec of atmospheric "seeing". The preliminary evaluation of OCD's fine tracking indicates that the uncompensated tracking error is approx. 3.3 micro rad compared to approx. 1.7 micro rad observed in the laboratory. Fine tracking performance was intermittent, primarily due to beacon fades on the OCD tracking sensor. The best bit error rates observed while

  4. Differential regulation of horizontally acquired and core genome genes by the bacterial modulator H-NS.

    Directory of Open Access Journals (Sweden)

    Rosa C Baños

    2009-06-01

    Full Text Available Horizontal acquisition of DNA by bacteria dramatically increases genetic diversity and hence successful bacterial colonization of several niches, including the human host. A relevant issue is how this newly acquired DNA interacts and integrates in the regulatory networks of the bacterial cell. The global modulator H-NS targets both core genome and HGT genes and silences gene expression in response to external stimuli such as osmolarity and temperature. Here we provide evidence that H-NS discriminates and differentially modulates core and HGT DNA. As an example of this, plasmid R27-encoded H-NS protein has evolved to selectively silence HGT genes and does not interfere with core genome regulation. In turn, differential regulation of both gene lineages by resident chromosomal H-NS requires a helper protein: the Hha protein. Tight silencing of HGT DNA is accomplished by H-NS-Hha complexes. In contrast, core genes are modulated by H-NS homoligomers. Remarkably, the presence of Hha-like proteins is restricted to the Enterobacteriaceae. In addition, conjugative plasmids encoding H-NS variants have hitherto been isolated only from members of the family. Thus, the H-NS system in enteric bacteria presents unique evolutionary features. The capacity to selectively discriminate between core and HGT DNA may help to maintain horizontally transmitted DNA in silent form and may give these bacteria a competitive advantage in adapting to new environments, including host colonization.

  5. Magneto-convective instabilities in horizontal cavities

    Science.gov (United States)

    Mistrangelo, Chiara; Bühler, Leo

    2016-02-01

    A linear stability analysis is performed to investigate the onset of convective motions in a flat cavity filled with liquid metal. A volumetric heat source is uniformly distributed in the fluid and a horizontal magnetic field is imposed. Walls perpendicular to the magnetic field are thermally insulating, and the top wall is isothermal and the bottom adiabatic. When a magnetic field is applied, electromagnetic forces tend to transform 3D convective flow structures into quasi-2D rolls aligned to the magnetic field. By integrating 3D equations along magnetic field lines, a quasi-2D mathematical model has been derived. A dissipation term in the 2D equations accounts for 3D viscous effects in boundary layers at Hartmann walls perpendicular to the magnetic field. The influence of various parameters on flow stability is investigated. The flow is stabilized by increasing the magnetic field intensity or the electric conductance of Hartmann walls and by reducing the aspect ratio of the cavity. Numerical simulations are performed to verify the analytical results and to describe the main convective flow patterns in the non-linear regime.

  6. Analysis of Near Horizontal Muons at HAWC

    Science.gov (United States)

    Barber, Ahron; HAWC Collaboration

    2017-01-01

    The HAWC (High Altitude Water Cherenkov) gamma ray observatory observes muons with nearly horizontal trajectories. HAWC is located at an altitude of 4100 meters a.s.l. on Sierra Negra in Mexico. The Gamma and Cosmic Ray detector is composed of 300 water tanks, 7.3 m in diameter and 4.5 m tall, spread over a physical area of 22,000 m2. Due to its thickness of 4.5 m, HAWC acts as a hodoscope capable of observing muons with trajectories at zenith angles greater than 75 degrees to just over 90 degrees. These muon trajectories have a unique signal in that they are linear and travel at nearly the speed of light. CORSIKA simulations indicate that these muons originate from high zenith angle cosmic ray events, where the air shower core is located at great distance from HAWC. I will present the angular distribution and rate at which HAWC observes these muon events. High Altitude Water Cherenkov Observatory.

  7. Horizontal Drop of 21- PWR Waste Package

    Energy Technology Data Exchange (ETDEWEB)

    A.K. Scheider

    2001-04-26

    The objective of this calculation is to determine the structural response of the waste package (WP) dropped horizontally from a specified height. The WP used for that purpose is the 21-Pressurized Water Reactor (PWR) WP. The scope of this document is limited to reporting the calculation results in terms of stress intensities. The information provided by the sketches (Attachment I) is that of the potential design of the type of WP considered in this calculation, and all obtained results are valid for that design only. This calculation is associated with the WP design and was performed by the Waste Package Design group in accordance with the ''Technical Work Plan for: Waste Package Design Description for LA'' (Ref. 16). AP-3.12Q, ''Calculations'' (Ref. 11) is used to perform the calculation and develop the document. The sketches attached to this calculation provide the potential dimensions and materials for the 21-PWR WP design.

  8. Yaw dynamics of horizontal axis wind turbines

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, A.C. (Utah Univ., Salt Lake City, UT (United States))

    1992-05-01

    Designers of a horizontal axis wind turbine yaw mechanism are faced with a difficult decision. They know that if they elect to use a yaw- controlled rotor then the system will suffer increased initial cost and increased inherent maintenance and reliability problems. On the other hand, if they elect to allow the rotor to freely yaw they known they will have to account for unknown and random, though bounded, yaw rates. They will have a higher-risk design to trade-off against the potential for cost savings and reliability improvement. The risk of a yaw-free system could be minimized if methods were available for analyzing and understanding yaw behavior. The complexity of yaw behavior has, until recently, discouraged engineers from developing a complete yaw analysis method. The objectives of this work are to (1) provide a fundamental understanding of free-yaw mechanics and the design concepts most effective at eliminating yaw problems, and (2) provide tested design tools and guidelines for use by free-yaw wind systems manufacturers. The emphasis is on developing practical and sufficiently accurate design methods.

  9. Horizontal plane head stabilization during locomotor tasks.

    Science.gov (United States)

    Cromwell, R L; Newton, R A; Carlton, L G

    2001-03-01

    Frequency characteristics of head stabilization were examined during locomotor tasks in healthy young adults(N = 8) who performed normal walking and 3 walking tasks designed to produce perturbations primarily in the horizontal plane. In the 3 walking tasks, the arms moved in phase with leg movement, with abnormally large amplitude, and at twice the frequency of leg movement. Head-in-space angular velocity was examined at the predominant frequencies of trunk motion. Head movements in space occurred at low frequencies ( 4.0 Hz) when the arms moved at twice the frequency of the legs. Head stabilization strategies were determined from head-on-trunk with respect to trunk frequency profiles derived from angular velocity data. During natural walking at low frequencies (head-on-trunk movement was less than trunk movement. At frequencies 3.0 Hz or greater, equal and opposite compensatory movement ensured head stability. When arm swing was altered, compensatory movement guaranteed head stability at all frequencies. Head stabilization was successful for frequencies up to 10.0 Hz during locomotor tasks. Maintaining head stability at high frequencies during voluntary tasks suggests that participants used feedforward mechanisms to coordinate head and trunk movements. Maintenance of head stability during dynamic tasks allows optimal conditions for vestibulo-ocular reflex function.

  10. Horizontal visibility graphs from integer sequences

    Science.gov (United States)

    Lacasa, Lucas

    2016-09-01

    The horizontal visibility graph (HVG) is a graph-theoretical representation of a time series and builds a bridge between dynamical systems and graph theory. In recent years this representation has been used to describe and theoretically compare different types of dynamics and has been applied to characterize empirical signals, by extracting topological features from the associated HVGs which have shown to be informative on the class of dynamics. Among some other measures, it has been shown that the degree distribution of these graphs is a very informative feature that encapsulates nontrivial information of the series's generative dynamics. In particular, the HVG associated to a bi-infinite real-valued series of independent and identically distributed random variables is a universal exponential law P(k)=(1/3){(2/3)}k-2, independent of the series marginal distribution. Most of the current applications have however only addressed real-valued time series, as no exact results are known for the topological properties of HVGs associated to integer-valued series. In this paper we explore this latter situation and address univariate time series where each variable can only take a finite number n of consecutive integer values. We are able to construct an explicit formula for the parametric degree distribution {P}n(k), which we prove to converge to the continuous case for large n and deviates otherwise. A few applications are then considered.

  11. The peculiar Horizontal Branch of NGC 2808

    CERN Document Server

    Dalessandro, E; Ferraro, F R; Cassisi, S; Lanzoni, B; Rood, R T; Pecci, F Fusi; Sabbi, E

    2010-01-01

    We present an accurate analysis of the peculiar Horizontal Branch (HB) of the massive Galactic globular cluster NGC 2808, based on high-resolution far-UV and optical images of the central region of the cluster obtained with HST. We confirm the multimodal distribution of stars along the HB: 4 sub-populations separated by gaps are distinguishable. The detailed comparison with suitable theoretical models showed that (i) it is not possible to reproduce the luminosity of the entire HB with a single helium abundance, while an appropriate modeling is possible for three HB groups by assuming different helium abundances in the range 0.24 < Y < 0.4 that are consistent with the multiple populations observed in the Main Sequence; (ii) canonical HB models are not able to properly match the observational properties of the stars populating the hottest end of the observed HB distribution, the so called "blue-hook region". These objects are probably "hot-flashers" , stars that peel off the red giant branch before reachi...

  12. Shallow water model for horizontal centrifugal casting

    Science.gov (United States)

    Boháček, J.; Kharicha, A.; Ludwig, A.; Wu, M.

    2012-07-01

    A numerical model was proposed to simulate the solidification process of an outer shell of work roll made by the horizontal centrifugal casting technique. Shallow water model was adopted to solve the 2D average flow dynamics of melt spreading and the average temperature distribution inside the centrifugal casting mould by considering the centrifugal force, Coriolis force, viscous force due to zero velocity on the mould wall, gravity, and energy transport by the flow. Additionally, a 1D sub-model was implemented to consider the heat transfer in the radial direction from the solidifying shell to the mould. The solidification front was tracked by fulfilling the Stefan condition. Radiative and convective heat losses were included from both, the free liquid surface and the outer wall of the mould. Several cases were simulated with the following assumed initial conditions: constant height of the liquid metal (10, 20, and 30 mm), uniform temperature of the free liquid surface (1755 K). The simulation results have shown that while the solidification front remained rather flat, the free surface was disturbed by waves. The amplitude of waves increased with the liquid height. Free surface waves diminished as the solidification proceeded.

  13. Speech disorders in students in Belo Horizonte.

    Science.gov (United States)

    Rabelo, Alessandra Terra Vasconcelos; Alves, Claudia Regina Lindgren; Goulart, Lúcia Maria H Figueiredo; Friche, Amélia Augusta de Lima; Lemos, Stela Maris Aguiar; Campos, Fernanda Rodrigues; Friche, Clarice Passos

    2011-12-01

    To describe speech disorders in students from 1st to 4th grades, and to investigate possible associations between these disorders and stomatognathic system and auditory processing disorders. Cross-sectional study with stratified random sample composed of 288 students, calculated based on an universe of 1,189 children enrolled in public schools from the area covered by a health center in Belo Horizonte. The median age was 8.9 years, and 49.7% were male. Assessment used a stomatognathic system protocol adapted from the Myofunctional Evaluation Guidelines, the Phonology task of the ABFW - Child Language Test, and a simplified auditory processing evaluation. Data were statistically analyzed. From the subjects studied, 31.9% had speech disorder. From these, 18% presented phonetic deviation, 9.7% phonological deviation, and 4.2% phonetic and phonological deviation. Linguistic variation was observed in 38.5% of the children. There was a higher proportion of children with phonetic deviation in 1st grade, and a higher proportion of children younger than 8 years old with both phonetic and phonological deviations. Phonetic deviation was associated to stomatognathic system disorder, and phonological deviation was associated to auditory processing disorder. The prevalence of speech disorders in 1st to 4th grade students is considered high. Moreover, these disorders are associated to other Speech-Language Pathology and Audiology alterations, which suggest that one disorder may be a consequence of the other, indicating the need for early diagnosis and intervention.

  14. Horizontal gene transfer in silkworm, Bombyx mori

    Directory of Open Access Journals (Sweden)

    Li Bin

    2011-05-01

    Full Text Available Abstract Background The domesticated silkworm, Bombyx mori, is the model insect for the order Lepidoptera, has economically important values, and has gained some representative behavioral characteristics compared to its wild ancestor. The genome of B. mori has been fully sequenced while function analysis of BmChi-h and BmSuc1 genes revealed that horizontal gene transfer (HGT maybe bestow a clear selective advantage to B. mori. However, the role of HGT in the evolutionary history of B. mori is largely unexplored. In this study, we compare the whole genome of B. mori with those of 382 prokaryotic and eukaryotic species to investigate the potential HGTs. Results Ten candidate HGT events were defined in B. mori by comprehensive sequence analysis using Maximum Likelihood and Bayesian method combining with EST checking. Phylogenetic analysis of the candidate HGT genes suggested that one HGT was plant-to- B. mori transfer while nine were bacteria-to- B. mori transfer. Furthermore, functional analysis based on expression, coexpression and related literature searching revealed that several HGT candidate genes have added important characters, such as resistance to pathogen, to B. mori. Conclusions Results from this study clearly demonstrated that HGTs play an important role in the evolution of B. mori although the number of HGT events in B. mori is in general smaller than those of microbes and other insects. In particular, interdomain HGTs in B. mori may give rise to functional, persistent, and possibly evolutionarily significant new genes.

  15. Efecto hipolipemiante del aceite de Sacha Inchi en adultos con hipercolesterolemia e hipertrigliceridemia de 35 - 64 años, Nuevo AA.HH. Nueva Alianza, Chaclacayo, Lima

    OpenAIRE

    Gamarra Camacho, María; Flores Albino, Betzabé; Palacios Morales, Félix

    2015-01-01

    Objetivo: Determinar el efecto hipolipemiante del aceite de Sacha Inchi (Plukenetia volúbilis linneo) administrado en personas con hipercolesterolemia e hipertrigliceridemía de 35 a 64 años en el AA. HH. Nueva Alianza - Chaclacayo. Material y métodos: Estudio de diseño preexperimental, de corte longitudinal prospectivo y de alcance explicativo. El grupo de participantes se conformó de 30 personas, en quienes se determinaron los valores sanguíneos de colesterol total (CT), colesterol (LDL), co...

  16. The Sinorhizobium (Ensifer) fredii HH103 Nodulation Outer Protein NopI Is a Determinant for Efficient Nodulation of Soybean and Cowpea Plants.

    Science.gov (United States)

    Jiménez-Guerrero, Irene; Pérez-Montaño, Francisco; Medina, Carlos; Ollero, Francisco Javier; López-Baena, Francisco Javier

    2017-03-01

    The type III secretion system (T3SS) is a specialized secretion apparatus that is commonly used by many plant and animal pathogenic bacteria to deliver proteins, termed effectors, to the interior of the host cells. These effectors suppress host defenses and interfere with signal transduction pathways to promote infection. Some rhizobial strains possess a functional T3SS, which is involved in the suppression of host defense responses, host range determination, and symbiotic efficiency. The analysis of the genome of the broad-host-range rhizobial strain Sinorhizobium fredii HH103 identified eight genes that code for putative T3SS effectors. Three of these effectors, NopL, NopP, and NopI, are Rhizobium specific. In this work, we demonstrate that NopI, whose amino acid sequence shows a certain similarity with NopP, is secreted through the S. fredii HH103 T3SS in response to flavonoids. We also determined that NopL can be considered an effector since it is directly secreted to the interior of the host cell as demonstrated by adenylate cyclase assays. Finally, the symbiotic phenotype of single, double, and triple nopI, nopL, and nopP mutants in soybean and cowpea was assayed, showing that NopI plays an important role in determining the number of nodules formed in both legumes and that the absence of both NopL and NopP is highly detrimental for symbiosis.IMPORTANCE The paper is focused on three Rhizobium-specific T3SS effectors of Sinorhizobium fredii HH103, NopL, NopP, and NopI. We demonstrate that S. fredii HH103 is able to secrete through the T3SS in response to flavonoids the nodulation outer protein NopI. Additionally, we determined that NopL can be considered an effector since it is secreted to the interior of the host cell as demonstrated by adenylate cyclase assays. Finally, nodulation assays of soybean and cowpea indicated that NopI is important for the determination of the number of nodules formed and that the absence of both NopL and NopP negatively affected

  17. Epitaxial growth of magnetoresistive (00h), (0hh), and (hhh) La2/3Sr1/3MnO3 thin films on (001)Si substrates

    Science.gov (United States)

    Fontcuberta, J.; Bibes, M.; Martínez, B.; Trtik, V.; Ferrater, C.; Sánchez, F.; Varela, M.

    1999-03-01

    We show that suitable choice of the buffer heterostructure allows us to obtain epitaxial (00h), (0hh), and (hhh) La2/3Sr1/3MnO3 thin films on buffered Si(001) substrates. The magnetotransport properties are investigated. Irrespective of the film texture, it is found that the easy-magnetization direction lies within the film plane. The low-field magnetoresistance is mainly controlled by the in-plane misorientation of crystallites while differences associated with the distinct microstructure of the interfaces appear to have only a second-order effect.

  18. Study of the physics potential of the FCC-hh machine to measure the coupling of the Higgs boson to b quarks

    CERN Document Server

    Rodríguez, Arturo

    2016-01-01

    The FCC project as well as the Pythia + Delphes analysis within the FCC software are introduced. The ROOT analysis carried out to reconstruct main observables, such the invariant mass of the bb system, transverse mass and momentum of the W boson together with the lepton pT and distribution is explained. The resulting reconstructed invariant mass of the bb system showed a peak near the 125 GeV in correspondence with the Higgs boson. Future steps towards estimating the physics potential of the FCC-hh machine in this channel are discussed.

  19. C-H and H-H bond activation via ligand dearomatization/rearomatization of a PN³P-rhodium(I) complex.

    Science.gov (United States)

    Wang, Yuan; Zheng, Bin; Pan, Yupeng; Pan, Chengling; He, Lipeng; Huang, Kuo-Wei

    2015-09-14

    A neutral complex PN(3)P-Rh(I)Cl (2) was prepared from a reaction of the PN(3)P pincer ligand (1) with [Rh(COD)Cl]2 (COD = 1,5-cyclooctadiene). Upon treatment with a suitable base, H-H and C(sp(2))-H activation reactions can be achieved through the deprotonation/reprotonation of one of the N-H arms and dearomatization/rearomatization of the central pyridine ring with the oxidation state of Rh remaining I.

  20. The Transmissibility of Sexually Transmitted Diseases in Sexually Abused Children.

    Science.gov (United States)

    Hammerschlag, Margaret R.

    1998-01-01

    This paper summarizes what is known about, and research needs on, the transmissibility to sexually abused children of the following sexually transmitted diseases: gonorrhea, chlamydia trachomatis, human papillomavirus genital warts, condylomata acuminata, syphilis, bacterial vaginosis, trichomonas vaginalis, herpes simplex, and human…

  1. Genetic Analyses of Sorting of Paternally Transmitted Mitochondrial DNA

    Science.gov (United States)

    The organelles are maternally transmitted in the vast majority of eukaryotes. However paternal transmission of plastids and mitochondria occurs rarely in plants. Cucumber is a unique model plant for organellar genetics because its three genomes show differential transmission: maternal for chlorop...

  2. Risk behaviors for sexually transmitted diseases among crack users

    Directory of Open Access Journals (Sweden)

    Rafael Alves Guimarães

    2015-08-01

    Full Text Available AbstractObjectives: to investigate the prevalence and risk behaviors by means of reporting of sexually transmitted diseases among crack users.Method: cross-sectional study carried out with 588 crack users in a referral care unit for the treatment of chemical dependency. Data were collected by means of face-to-face interview and analyzed using Stata statistical software, version 8.0.Results: of the total participants, 154 (26.2%; 95% CI: 22.8-29.9 reported antecedents of sexually transmitted diseases. Ages between 25 and 30 years (RP: 2.1; 95% CI: 1.0-4.0 and over 30 years (RP: 3.8; 95% CI: 2.1-6.8, alcohol consumption (RP: 1.9; 95% CI: 1.1-3.3, antecedents of prostitution (RP: 1.9; 95% CI: 1.3-2.9 and sexual intercourse with person living with human immunodeficiency virus/AIDS (RP: 2.7; 95% CI: 1.8-4.2 were independently associated with reporting of sexually transmitted diseases.Conclusion: the results of this study suggest high risk and vulnerability of crack users for sexually transmitted diseases.

  3. Adolescent Sexuality: Pregnancy, Sexually Transmitted Diseases, and Prevention.

    Science.gov (United States)

    Santelli, John S.; And Others

    1992-01-01

    Special edition discusses adolescent sexuality, focusing on pregnancy, sexually transmitted diseases, and prevention. The articles focus on demographics, risk factors, school-based risk reduction programs, contraception, early intervention, options, school-based prenatal and postpartum care programs, teenage parenting, abortion, HIV and AIDS,…

  4. Sexually transmitted infection incidence among adolescents in Ireland.

    LENUS (Irish Health Repository)

    Davoren, Martin P

    2014-10-01

    The burden of sexually transmitted infections (STIs) rests with young people, yet in Ireland there has been very little research into this population. The purpose of this study was to determine the incidence rate and establish risk factors that predict STI occurrence among adolescents in Ireland.

  5. CONSTRUCTIONS OF THREE-TRANSMIT-ANTENNA SPACE-TIME CODES

    Institute of Scientific and Technical Information of China (English)

    Hongxi TONG; Fei YU

    2007-01-01

    In this paper, we give design methods for three-transmit-antenna space-time codes which have reasonable parameters. A few examples are given to show that some unitary space-time codes constructed with our methods are better than the previously best-known ones.

  6. The Silent Epidemic. Teens and Sexually Transmitted Diseases.

    Science.gov (United States)

    Francis, Susan

    1998-01-01

    One-quarter of the 3 million new cases of sexually transmitted diseases (STDs) each year occur in teenagers. Teens are at high risk because of biological, age, and behavioral factors. Education is the best weapon against STDs. As their children's first sex educators, parents must make every effort to promote STD education at home and school. (SM)

  7. Adaptive single-antenna transmit selection with interference suppression

    KAUST Repository

    Radaydeh, Redha Mahmoud Mesleh

    2011-10-01

    This paper studies the performance of adaptive transmit selection with co-channel interference suppression in multipath fading channels. The adaptive selection algorithms are configured for single-antenna bandwidth-efficient or power-efficient transmission with as low transmit channel estimations as possible. Due to the fact that the number of active co-channel interfering signals and their corresponding powers experience random behavior, the adaptation to channels conditions, assuming uniform buffer and traffic loading, is proposed to be jointly based on the transmit channels instantaneous signal-to-noise ratios (SNRs) and signal-to-interference-plus-noise ratios (SINRs). Two interference cancelation algorithms are considered. The first algorithm assumes that the receiver eliminates the impact of the strongest subset of interferers, whereas the second algorithm suggests random cancelation of interferers to further reduce processing complexity. The impact of outdated ordering of interferers powers on the efficiency of interference cancelation, and the effect of imperfect prediction of transmit channels for desired user adaptation are investigated. Analytical formulations for various performance measures and comparisons between the performance and processing complexity of different adaptation schemes are presented. © 2011 IEEE.

  8. HIV and Sexually Transmitted Infections in the Netherlands in 2003

    NARCIS (Netherlands)

    Laar MJW van de; Op de Coul ELM; CIE

    2004-01-01

    The increasing trend of Sexually Transmitted Infections (STIs), as observed in the last few years, seemed to have stabilised in 2003. The continuous increase of syphilis diagnoses and the outbreak of Lymphogranuloma venereum (LGV) among men who have sex with men (MSM), indicate an increase of sexual

  9. Sex Partner with No Zika Symptoms Transmits Virus: CDC

    Science.gov (United States)

    ... news/fullstory_160643.html Sex Partner With No Zika Symptoms Transmits Virus: CDC New report also highlights ties between Zika ... HealthDay News) -- U.S. health officials report that the Zika virus can be spread sexually even when a partner ...

  10. Young Male Prostitutes: Their Knowledge of Selected Sexually Transmitted Diseases.

    Science.gov (United States)

    Calhoun, Thomas; Pickerill, Brian

    1988-01-01

    Conducted unstructured interviews with 18 male street prostitutes between the ages of 13 and 22 to determine the extent of accurate knowledge they possessed concerning four common sexually transmitted diseases. Found that subjects possessed more factual information on gonorrhea and syphilis than on herpes and Acquired Immune Deficiency Syndrome.…

  11. Knowledge of Sexually Transmitted infections among High School Students

    Science.gov (United States)

    Nsuami, M. Jacques; Sanders, Ladatra S.; Taylor, Stephanie N.

    2010-01-01

    Background: It has not been determined conclusively whether greater knowledge of sexually transmitted infections (STIs) is associated with lower rates of STIs. Purpose: This study sought to determine STI knowledge among high school students and factors associated with such knowledge, and to determine whether poor STI knowledge is associated with…

  12. Fourier-Based Transmit Beampattern Design Using MIMO Radar

    KAUST Repository

    Lipor, John

    2014-05-01

    In multiple-input multiple-output (MIMO) radar settings, it is often desirable to transmit power only to a given location or set of locations defined by a beampattern. Transmit waveform design is a topic that has received much attention recently, involving synthesis of both the signal covariance matrix,, as well as the actual waveforms. Current methods involve a two-step process of designing via iterative solutions and then using to generate waveforms that fulfill practical constraints such as having a constant-envelope or drawing from a finite alphabet. In this paper, a closed-form method to design for a uniform linear array is proposed that utilizes the discrete Fourier transform (DFT) coefficients and Toeplitz matrices. The resulting covariance matrix fulfills the practical constraints such as positive semidefiniteness and the uniformelemental power constraint and provides performance similar to that of iterative methods, which require a much greater computation time. Next, a transmit architecture is presented that exploits the orthogonality of frequencies at discrete DFT values to transmit a sum of orthogonal signals from each antenna. The resulting waveforms provide a lower mean-square error than current methods at a much lower computational cost, and a simulated detection scenario demonstrates the performance advantages achieved.

  13. Sexually Transmitted Disease Prevention: Adolescents' Perceptions of Possible Side Effects.

    Science.gov (United States)

    Furby, Lita; Ochs, Linda M.; Thomas, Catherine W.

    1997-01-01

    Reports on interviews of 48 sexually active adolescents concerning the possible secondary consequences of taking measures to reduce the risk of contracting a sexually transmitted disease (STD). Adolescents generated 134 consequences, suggesting that considering all the relevant consequences for a rational decision about STD prevention is not…

  14. The prevalence of transfusion transmitted virus infection in blood donors

    Institute of Scientific and Technical Information of China (English)

    Cheng Hui Huang; Ru Guang Chen; Yu Sen Zhou; Hai Tao Wang; Chun Ying Xie

    2000-01-01

    @@INTRODUCTION A newly discovered DNA virus,transfusion transmitted virus (TTV), was reported as a cause of post-transfusion hepatitis of unknown etiology in Japan[1]. In order to investigate TTV prevalence in southern China, a study was carried out among blood donors, patients with liver diseases and hemodialysis to determine the epidemiological charateristics.

  15. HIV and Sexually Transmitted Infections in the Netherlands in 2005

    NARCIS (Netherlands)

    Boer IM de; Op de Coul ELM; Koedijk FDH; Veen MG van; Sighem AI van; Laar MJW van de; CIE

    2006-01-01

    The trend of increasing Sexually Transmitted Infections (STI) has partly stabilised in 2005 in the STI sentinel surveillance network. Among men having sex with men (MSM), the number of STI diagnoses remained high and the HIV positivity rate has increased. Moreover, in the national HIV registry (HIV

  16. Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis

    NARCIS (Netherlands)

    Carlton, Jane M.; Hirt, Robert P.; Silva, Joana C.; Delcher, Arthur L.; Schatz, Michael; Zhao, Qi; Wortman, Jennifer R.; Bidwell, Shelby L.; Alsmark, U. Cecilia M.; Besteiro, Sebastien; Sicheritz-Ponten, Thomas; Noel, Christophe J.; Dacks, Joel B.; Foster, Peter G.; Simillion, Cedric; Van de Peer, Yves; Miranda-Saavedra, Diego; Barton, Geoffrey J.; Westrop, Gareth D.; Mueller, Sylke; Dessi, Daniele; Fiori, Pier Luigi; Ren, Qinghu; Paulsen, Ian; Zhang, Hanbang; Bastida-Corcuera, Felix D.; Simoes-Barbosa, Augusto; Brown, Mark T.; Hayes, Richard D.; Mukherjee, Mandira; Okumura, Cheryl Y.; Schneider, Rachel; Smith, Alias J.; Vanacova, Stepanka; Villalvazo, Maria; Haas, Brian J.; Pertea, Mihaela; Feldblyum, Tamara V.; Utterback, Terry R.; Shu, Chung-Li; Osoegawa, Kazutoyo; de Jong, Pieter J.; Hrdy, Ivan; Horvathova, Lenka; Zubacova, Zuzana; Dolezal, Pavel; Malik, Shehre-Banoo; Logsdon, John M.; Henze, Katrin; Gupta, Arti; Wang, Ching C.; Dunne, Rebecca L.; Upcroft, Jacqueline A.; Upcroft, Peter; White, Owen; Salzberg, Steven L.; Tang, Petrus; Chiu, Cheng-Hsun; Lee, Ying-Shiung; Embley, T. Martin; Coombs, Graham H.; Mottram, Jeremy C.; Tachezy, Jan; Fraser-Liggett, Claire M.; Johnson, Patricia J.

    2007-01-01

    We describe the genome sequence of the protist Trichomonas vaginalis, a sexually transmitted human pathogen. Repeats and transposable elements comprise about two-thirds of the similar to 160-megabase genome, reflecting a recent massive expansion of genetic material. This expansion, in conjunction wi

  17. Sexually transmitted infections, including HIV, in the Netherlands in 2014.

    NARCIS (Netherlands)

    Oeffelen, A.A.M. van; Aar, F. van; Broek, I.V.F. van den; Coul, E.L.M. Op de; Woestenberg, P.J.; Heijne, J.C.M.; Daas, C. den; Hofstraat, S.H.I.; Sighem, A.I. van; Nielen, M.M.J.; Benthem, B.H.B. van

    2015-01-01

    In 2013, more people were tested for sexually transmitted infections (STI) at Dutch STI clinics than in previous years. Although the percentage of people with an STI showed a slight decrease (0.4 per cent) for the first time since 2007, it remained high at 14.7 per cent. Effective STI monitoring

  18. Sexually transmitted infections, including HIV, in the Netherlands in 2013.

    NARCIS (Netherlands)

    Aar, F. van; Koedijk, F.D.H.; Broek, I.V.F. van den; Coul, E.L.M. Op de; Soetens, L.C.; Woestenberg, P.J.; Heijne, J.C.M.; Sighem, A.I. van; Nielen, M.M.J.; Benthem, B.H.B. van

    2014-01-01

    In 2013, more people were tested for sexually transmitted infections (STI) at Dutch STI clinics than in previous years. Although the percentage of people with an STI showed a slight decrease (0.4 per cent) for the first time since 2007, it remained high at 14.7 per cent. Effective STI monitoring

  19. Intimate partner violence after the diagnosis of sexually transmitted diseases.

    Science.gov (United States)

    Andrade, Roumayne Fernandes Vieira; Araújo, Maria Alix Leite; Vieira, Luiza Jane Eyre de Souza; Reis, Cláudia Bastos Silveira; Miranda, Angélica Espinosa

    2015-01-01

    OBJECTIVE To assess the prevalence and factors associated with intimate partner violence after the diagnosis of sexually transmitted diseases. METHODS This cross-sectional study was conducted in Fortaleza, CE, Northeastern Brazil, in 2012 and involved 221 individuals (40.3% male and 59.7% female) attended to at reference health care units for the treatment of sexually transmitted diseases. Data were collected using a questionnaire applied during interviews with each participant. A multivariate analysis with a logistic regression model was conducted using the stepwise technique. Only the variables with a p value sexually transmitted diseases, the following variables remained statistically significant: extramarital relations (OR = 3.72; 95%CI 1.91;7.26; p = 0.000), alcohol consumption by the partner (OR = 2.16; 95%CI 1.08;4.33; p = 0.026), history of violence prior to diagnosis (OR = 2.87; 95%CI 1.44;5.69; p = 0.003), and fear of disclosing the diagnosis to the partner (OR = 2.66; 95%CI 1.32;5.32; p = 0.006). CONCLUSIONS Individuals who had extramarital relations, experienced violence prior to the diagnosis of sexually transmitted disease, feared disclosing the diagnosis to the partner, and those whose partner consumed alcohol had an increased likelihood of suffering violence. The high prevalence of intimate partner violence suggests that this population is vulnerable and therefore intervention efforts should be directed to them. Referral health care services for the treatment of sexually transmitted diseases can be strategic places to identify and prevent intimate partner violence.

  20. Ratio between vertical and horizontal mandibular range of motion

    NARCIS (Netherlands)

    Dijkstra, P.U.; Kropmans, T.J.B.; Stegenga, B; de Bont, L.G.M.

    1998-01-01

    Mandibular range of motion (ROM), vertical and horizontal, is often measured as a part of a diagnostic assessment of temporomandibular joint disorders. Ln the literature, a fixed ratio between the vertical and the horizontal ROM has been suggested, i.e. 4:1. The ratio is frequently used to predict t

  1. Horizontal drilling methods proven in three test wells

    Energy Technology Data Exchange (ETDEWEB)

    Dorel, M.

    1983-05-01

    The practice of drilling horizontally through a reservoir by deviating the wellbore 90/sup 0/ from vertical requires precise planning and sound engineering practices. This article takes a look at the operational, engineering and planning aspects of three successfully drilled drainholes. It also presents a field-tested horizontal well logging procedure that may help extend and improve this technology.

  2. Horizontal Coherence of Wave Forces on Vertical Wall Breakwaters

    DEFF Research Database (Denmark)

    Archetti, R.; Frigaard, Peter; Lamberti, A.

    2001-01-01

    of breaking waves for increasing wave height are estimated and compared with existing empirical formulae. The horizontal dimension of the breaker is investigated using two different methodologies: the first analyses the decreasing of the highest 1/250 force with increasing horizontal dimension of the caisson...

  3. Steerable vertical to horizontal energy transducer for mobile robots

    Science.gov (United States)

    Spletzer, Barry L.; Fischer, Gary J.; Feddema, John T.

    2001-01-01

    The present invention provides a steerable vertical to horizontal energy transducer for mobile robots that less complex and requires less power than two degree of freedom tilt mechanisms. The present invention comprises an end effector that, when mounted with a hopping actuator, translates along axis (typically vertical) actuation into combined vertical and horizontal motion. The end effector, or foot, mounts with an end of the actuator that moves toward the support surface (typically a floor or the earth). The foot is shaped so that the first contact with the support surface is off the axis of the actuator. Off-axis contact with the support surface generates an on-axis force (typically resulting in vertical motion) and a moment orthogonal to the axis. The moment initiates a horizontal tumbling motion, and tilts the actuator so that its axis is oriented with a horizontal component and continued actuation generates both vertical and horizontal force.

  4. A horizontal well analysis from a view of its productivity

    Directory of Open Access Journals (Sweden)

    Lucia Sciranková

    2006-10-01

    Full Text Available The 1990s may become known in the oil field as the decade of the horizontal well. Horizontal wells can increase the production rate and the ultimate recovery, and can reduce the number of platforms on wells required to develop a reservoir.An empirical equation to calculate the inflow performance of two-phase flow for a vertical and a horizontal well in regime of dissolved gas presented by Vogel in 1968. His equation was based on the results of reservoir simulation. The created model whore result (output is the ratio of the productivity of a horizontal well to the productivity of a vertical well for a given area expressed by anumber of vertical wells the replaced by one horizontal well. The model is applied for a concrete ideological model.

  5. Horizontal crustal movement in Chinese mainland from 1999 to 2001

    Institute of Scientific and Technical Information of China (English)

    顾国华; 符养; 王武星

    2004-01-01

    The paper introduces the horizontal crustal movement obtained from GPS observations in the regional networks(including the basic network and the fiducial network) of the Crustal Movement Observation Network of China(CMONOC) carried out in 1999 and 2001. This paper is characterized by the acquisition of the horizontal dis-placement velocities during the period from 1999 to 2001 at the observation stations in the regional networks withdatum definition of a group of stable stations with small mutual displacements in east China. Based on the mostdetailed map of horizontal crustal movement in Chinese mainland, the division of blocks, their displacements anddeformations are studied. An approach to analysis of the intensity of the horizontal crustal deformation is proposed.The general characteristics of the recent horizontal crustal movement in Chinese mainland and that before theKunlunshan earthquake of M=8.1 on November 14, 2001 are analyzed.

  6. Trends in sexually transmitted infections in the Netherlands, combining surveillance data from general practices and sexually transmitted infection centers.

    NARCIS (Netherlands)

    Broek, I.V.F. van den; Verheij, R.A.; Dijk, C. van; Koedijk, F.D.H.; Sande, M.A.B. van der; Bergen, J.E.A.M. van

    2010-01-01

    Background: Sexually transmitted infections (STI) care in the Netherlands is primarily provided by general practitioners (GPs) and specialized STI centers. STI surveillance is based on data from STI centers, which show increasing numbers of clients. Data from a GP morbidity surveillance network were

  7. Simulations and scaling of horizontal convection

    Directory of Open Access Journals (Sweden)

    Mehmet ILIcak

    2012-05-01

    Full Text Available In this paper we describe the results of various numerical simulations of sideways or horizontal convection. Specifically, a two-dimensional Boussinesq fluid is both heated and cooled from its upper surface, but the walls and the bottom of the tank are insulating and have no flux of heat through them. We perform experiments with a range of Rayleigh numbers up to 1011, obtained by systematically reducing the diffusivity. We also explore the effects of a nonlinear equation of state and of a mechanical force imposed on the top surface at a fixed Rayleigh number. We find that, when there is no mechanical forcing, both the energy dissipation and the strength of the circulation itself monotonically fall with decreasing diffusivity. At Rayleigh numbers greater than 1010 the flow is unsteady; however, the eddying flow is still much weaker than the steady flow at smaller Rayleigh numbers. At high Rayleigh numbers, the stratification and the mean circulation are increasingly confined to a thin layer at the upper surface, with the layer thickness decreasing according to Ra−1/5. There is no evidence that the flow ever enters a regime that is independent of Rayleigh number. Using a nonlinear equation of state makes little difference to the flow phenomenology at a moderate Rayleigh number. The addition of an imposed stress at the upper surface makes a significant difference in the flow. A strong, energy-dissipating circulation can be maintained even at Ra = 109, and the stratification extends more deeply into the fluid than in the unstressed case. Overall, our results are consistent with the notion that in the absence of mechanical forcing a fluid that is heated and cooled from above cannot maintain a deep stratification or a strong sustained flow at high Rayleigh numbers, even if the interior flow is unsteady.

  8. Searches for Higgs boson pair production in the $hh\\to bb\\tau\\tau, \\gamma\\gamma WW*, \\gamma\\gamma bb, bbbb$ channels with the ATLAS detector

    CERN Document Server

    Aad, Georges; Abdallah, Jalal; Abdinov, Ovsat; Aben, Rosemarie; Abolins, Maris; AbouZeid, Ossama; Abramowicz, Halina; Abreu, Henso; Abreu, Ricardo; Abulaiti, Yiming; Acharya, Bobby Samir; Adamczyk, Leszek; Adams, David; Adelman, Jahred; Adomeit, Stefanie; Adye, Tim; Affolder, Tony; Agatonovic-Jovin, Tatjana; Agricola, Johannes; Aguilar-Saavedra, Juan Antonio; Ahlen, Steven; Ahmadov, Faig; Aielli, Giulio; Akerstedt, Henrik; Åkesson, Torsten Paul Ake; Akimov, Andrei; Alberghi, Gian Luigi; Albert, Justin; Albrand, Solveig; Alconada Verzini, Maria Josefina; Aleksa, Martin; Aleksandrov, Igor; Alexa, Calin; Alexander, Gideon; Alexopoulos, Theodoros; Alhroob, Muhammad; Alimonti, Gianluca; Alio, Lion; Alison, John; Alkire, Steven Patrick; Allbrooke, Benedict; Allport, Phillip; Aloisio, Alberto; Alonso, Alejandro; Alonso, Francisco; Alpigiani, Cristiano; Altheimer, Andrew David; Alvarez Gonzalez, Barbara; Άlvarez Piqueras, Damián; Alviggi, Mariagrazia; Amadio, Brian Thomas; Amako, Katsuya; Amaral Coutinho, Yara; Amelung, Christoph; Amidei, Dante; Amor Dos Santos, Susana Patricia; Amorim, Antonio; Amoroso, Simone; Amram, Nir; Amundsen, Glenn; Anastopoulos, Christos; Ancu, Lucian Stefan; Andari, Nansi; Andeen, Timothy; Anders, Christoph Falk; Anders, Gabriel; Anders, John Kenneth; Anderson, Kelby; Andreazza, Attilio; Andrei, George Victor; Angelidakis, Stylianos; Angelozzi, Ivan; Anger, Philipp; Angerami, Aaron; Anghinolfi, Francis; Anisenkov, Alexey; Anjos, Nuno; Annovi, Alberto; Antonelli, Mario; Antonov, Alexey; Antos, Jaroslav; Anulli, Fabio; Aoki, Masato; Aperio Bella, Ludovica; Arabidze, Giorgi; Arai, Yasuo; Araque, Juan Pedro; Arce, Ayana; Arduh, Francisco Anuar; Arguin, Jean-Francois; Argyropoulos, Spyridon; Arik, Metin; Armbruster, Aaron James; Arnaez, Olivier; Arnold, Hannah; Arratia, Miguel; Arslan, Ozan; Artamonov, Andrei; Artoni, Giacomo; Asai, Shoji; Asbah, Nedaa; Ashkenazi, Adi; Åsman, Barbro; Asquith, Lily; Assamagan, Ketevi; Astalos, Robert; Atkinson, Markus; Atlay, Naim Bora; Augsten, Kamil; Aurousseau, Mathieu; Avolio, Giuseppe; Axen, Bradley; Ayoub, Mohamad Kassem; Azuelos, Georges; Baak, Max; Baas, Alessandra; Baca, Matthew John; Bacci, Cesare; Bachacou, Henri; Bachas, Konstantinos; Backes, Moritz; Backhaus, Malte; Bagiacchi, Paolo; Bagnaia, Paolo; Bai, Yu; Bain, Travis; Baines, John; Baker, Oliver Keith; Baldin, Evgenii; Balek, Petr; Balestri, Thomas; Balli, Fabrice; Balunas, William Keaton; Banas, Elzbieta; Banerjee, Swagato; Bannoura, Arwa A E; Barak, Liron; Barberio, Elisabetta Luigia; Barberis, Dario; Barbero, Marlon; Barillari, Teresa; Barisonzi, Marcello; Barklow, Timothy; Barlow, Nick; Barnes, Sarah Louise; Barnett, Bruce; Barnett, Michael; Barnovska, Zuzana; Baroncelli, Antonio; Barone, Gaetano; Barr, Alan; Barreiro, Fernando; Barreiro Guimarães da Costa, João; Bartoldus, Rainer; Barton, Adam Edward; Bartos, Pavol; Basalaev, Artem; Bassalat, Ahmed; Basye, Austin; Bates, Richard; Batista, Santiago Juan; Batley, Richard; Battaglia, Marco; Bauce, Matteo; Bauer, Florian; Bawa, Harinder Singh; Beacham, James Baker; Beattie, Michael David; Beau, Tristan; Beauchemin, Pierre-Hugues; Beccherle, Roberto; Bechtle, Philip; Beck, Hans Peter; Becker, Kathrin; Becker, Maurice; Beckingham, Matthew; Becot, Cyril; Beddall, Andrew; Beddall, Ayda; Bednyakov, Vadim; Bee, Christopher; Beemster, Lars; Beermann, Thomas; Begel, Michael; Behr, Janna Katharina; Belanger-Champagne, Camille; Bell, William; Bella, Gideon; Bellagamba, Lorenzo; Bellerive, Alain; Bellomo, Massimiliano; Belotskiy, Konstantin; Beltramello, Olga; Benary, Odette; Benchekroun, Driss; Bender, Michael; Bendtz, Katarina; Benekos, Nektarios; Benhammou, Yan; Benhar Noccioli, Eleonora; Benitez Garcia, Jorge-Armando; Benjamin, Douglas; Bensinger, James; Bentvelsen, Stan; Beresford, Lydia; Beretta, Matteo; Berge, David; Bergeaas Kuutmann, Elin; Berger, Nicolas; Berghaus, Frank; Beringer, Jürg; Bernard, Clare; Bernard, Nathan Rogers; Bernius, Catrin; Bernlochner, Florian Urs; Berry, Tracey; Berta, Peter; Bertella, Claudia; Bertoli, Gabriele; Bertolucci, Federico; Bertsche, Carolyn; Bertsche, David; Besana, Maria Ilaria; Besjes, Geert-Jan; Bessidskaia Bylund, Olga; Bessner, Martin Florian; Besson, Nathalie; Betancourt, Christopher; Bethke, Siegfried; Bevan, Adrian John; Bhimji, Wahid; Bianchi, Riccardo-Maria; Bianchini, Louis; Bianco, Michele; Biebel, Otmar; Biedermann, Dustin; Bieniek, Stephen Paul; Biesuz, Nicolo Vladi; Biglietti, Michela; Bilbao De Mendizabal, Javier; Bilokon, Halina; Bindi, Marcello; Binet, Sebastien; Bingul, Ahmet

    2015-01-01

    Searches for both resonant and non-resonant Higgs boson pair production are performed in the $hh\\to bb\\tau\\tau, \\gamma\\gamma WW^*$ final states using 20.3 fb$^{-1}$ of $pp$ collision data at a center-of-mass energy of 8 TeV recorded with the ATLAS detector at the Large Hadron Collider. No evidence of their production is observed and 95% confidence level upper limits on the production cross sections are set. These results are then combined with the published results of the $hh\\to \\gamma\\gamma bb, bbbb$ analyses. An upper limit of 0.69 (0.47) pb on the non-resonant Standard Model like $hh$ production is observed (expected), corresponding to 70 (48) times of the SM $gg\\to hh$ cross section. For production via narrow resonances, cross section limits of $hh$ production from a heavy Higgs boson decay are set as a function of the heavy Higgs boson mass. The observed (expected) limits range from 2.1 (1.1) pb at 260 GeV to 0.011 (0.018) pb at 1000 GeV. These results are interpreted in the context of two simplified sce...

  9. Effect of Horizontal Vibration on the Interfacial Instability in a Horizontal Hele-Shaw Cell

    Directory of Open Access Journals (Sweden)

    Souhar M.

    2012-07-01

    Full Text Available The effect of periodic oscillations on the interfacial instability of two immiscible fluids, confined in a horizontal Hele-Shaw cell, is investigated. A linear stability analysis of the basic state leads to a periodic Mathieu oscillator corresponding to the amplitude of the interface. Then, the threshold of parametric instability of the interface is characterized by harmonic or subharmonic periodic solutions. We show that the relevant parameters that control the interface are the Bond number, density ratio, Weber number and amplitude and frequency of oscillations.

  10. PdBI sub-arcsecond study of the SiO microjet in HH212 - Origin and collimation of Class 0 jets

    CERN Document Server

    Cabrit, S; Gueth, F; Nisini, B; Gusdorf, A; Dougados, C; Bacciotti, F

    2007-01-01

    The bipolar HH 212 outflow has been mapped in SiO using the extended configuration of the Plateau de Bure Interferometer (PdBI), revealing a highly collimated SiO jet closely associated with the H2 jet component. We study at unprecedented resolution (0.34" across the jet axis) the properties of the innermost SiO ``microjet'' within 1000 AU of this young Class 0 source, to compare it with atomic microjets from more evolved sources and to constrain its origin. The SiO channel maps are used to investigate the microjet collimation and velocity structure. A large velocity gradient analysis is applied to SiO (2-1), (5-4) and (8-7) data from the PdBI and the Submillimeter Array to constrain the SiO opacity and abundance. The HH212 Class 0 microjet shows striking similarities in collimation and energetic budget with atomic microjets from T Tauri sources. Furthermore, the SiO lines appear optically thick, unlike what is generally assumed. We infer T(kin) ~ 50-500 K and an SiO/H2 abundance greater than 4 10(-8)-6 10(-5...

  11. Biomechanics of the chick embryonic heart outflow tract at HH18 using 4D optical coherence tomography imaging and computational modeling.

    Directory of Open Access Journals (Sweden)

    Aiping Liu

    Full Text Available During developmental stages, biomechanical stimuli on cardiac cells modulate genetic programs, and deviations from normal stimuli can lead to cardiac defects. Therefore, it is important to characterize normal cardiac biomechanical stimuli during early developmental stages. Using the chicken embryo model of cardiac development, we focused on characterizing biomechanical stimuli on the Hamburger-Hamilton (HH 18 chick cardiac outflow tract (OFT, the distal portion of the heart from which a large portion of defects observed in humans originate. To characterize biomechanical stimuli in the OFT, we used a combination of in vivo optical coherence tomography (OCT imaging, physiological measurements and computational fluid dynamics (CFD modeling. We found that, at HH18, the proximal portion of the OFT wall undergoes larger circumferential strains than its distal portion, while the distal portion of the OFT wall undergoes larger wall stresses. Maximal wall shear stresses were generally found on the surface of endocardial cushions, which are protrusions of extracellular matrix onto the OFT lumen that later during development give rise to cardiac septa and valves. The non-uniform spatial and temporal distributions of stresses and strains in the OFT walls provide biomechanical cues to cardiac cells that likely aid in the extensive differential growth and remodeling patterns observed during normal development.

  12. Observations and measurements of dynamic effects due to beam-beam interactions in the LHC and extrapolation to the FCC-hh

    CERN Document Server

    Goncalves Jorge, Patrik

    The Future Circular hadron-hadron Collider (FCC-hh) is a design study for a 100 TeV centre-of-mass energy. The dynamics of the beams in such a collider poses many challenges, in particular the amount of energy stored in each beam (8.4 GJ) makes them very destructive and therefore requires a tight control of the machine and beam parameters during the full cycle in order to avoid damages and reach the collider designed performances. The FCC-hh features an increase of the beam brightness during the cycle due to the presence of synchrotron radiation damping at high energy. As a result, the electromagnetic forces that the two beams exert on each other, the so-called beam-beam forces, are enhanced and might become an issue for the safe operation of the machine. In this new regime, the impact of the beam-beam interaction on the optics becomes non-negligible. In this master thesis, for the first time, the impact of the beam-beam interaction on the optics ($\\beta$-beating) is measured in a hadron collider (LHC). The e...

  13. Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population.

    Directory of Open Access Journals (Sweden)

    Michele Mishto

    Full Text Available BACKGROUND: Albeit several studies pointed out the pivotal role that CD4+T cells have in Multiple Sclerosis, the CD8+ T cells involvement in the pathology is still in its early phases of investigation. Proteasome degradation is the key step in the production of MHC class I-restricted epitopes and therefore its activity could be an important element in the activation and regulation of autoreactive CD8+ T cells in Multiple Sclerosis. METHODOLOGY/PRINCIPAL FINDINGS: Immunoproteasomes and PA28-alphabeta regulator are present in MS affected brain area and accumulated in plaques. They are expressed in cell types supposed to be involved in MS development such as neurons, endothelial cells, oligodendrocytes, macrophages/macroglia and lymphocytes. Furthermore, in a genetic study on 1262 Italian MS cases and 845 controls we observed that HLA-A*02+ female subjects carrying the immunoproteasome LMP2 codon 60HH variant have a reduced risk to develop MS. Accordingly, immunoproteasomes carrying the LMP2 60H allele produce in vitro a lower amount of the HLA-A*0201 restricted immunodominant epitope MBP(111-119. CONCLUSION/SIGNIFICANCE: The immunoproteasome LMP2 60HH variant reduces the risk to develop MS amongst Italian HLA-A*02+ females. We propose that such an effect is mediated by the altered proteasome-dependent production of a specific MBP epitope presented on the MHC class I. Our observations thereby support the hypothesis of an involvement of immunoproteasome in the MS pathogenesis.

  14. Ability of innate defence regulator peptides IDR-1002, IDR-HH2 and IDR-1018 to protect against Mycobacterium tuberculosis infections in animal models.

    Directory of Open Access Journals (Sweden)

    Bruno Rivas-Santiago

    Full Text Available Tuberculosis is an ongoing threat to global health, especially with the emergence of multi drug-resistant (MDR and extremely drug-resistant strains that are motivating the search for new treatment strategies. One potential strategy is immunotherapy using Innate Defence Regulator (IDR peptides that selectively modulate innate immunity, enhancing chemokine induction and cell recruitment while suppressing potentially harmful inflammatory responses. IDR peptides possess only modest antimicrobial activity but have profound immunomodulatory functions that appear to be influential in resolving animal model infections. The IDR peptides HH2, 1018 and 1002 were tested for their activity against two M. tuberculosis strains, one drug-sensitive and the other MDR in both in vitro and in vivo models. All peptides showed no cytotoxic activity and only modest direct antimicrobial activity versus M. tuberculosis (MIC of 15-30 µg/ml. Nevertheless peptides HH2 and 1018 reduced bacillary loads in animal models with both the virulent drug susceptible H37Rv strain and an MDR isolate and, especially 1018 led to a considerable reduction in lung inflammation as revealed by decreased pneumonia. These results indicate that IDR peptides have potential as a novel immunotherapy against TB.

  15. Intimate partner violence after the diagnosis of sexually transmitted diseases

    Directory of Open Access Journals (Sweden)

    Roumayne Fernandes Vieira Andrade

    2015-01-01

    Full Text Available OBJECTIVE To assess the prevalence and factors associated with intimate partner violence after the diagnosis of sexually transmitted diseases. METHODS This cross-sectional study was conducted in Fortaleza, CE, Northeastern Brazil, in 2012 and involved 221 individuals (40.3% male and 59.7% female attended to at reference health care units for the treatment of sexually transmitted diseases. Data were collected using a questionnaire applied during interviews with each participant. A multivariate analysis with a logistic regression model was conducted using the stepwise technique. Only the variables with a p value < 0.05 were included in the adjusted analysis. The odds ratio (OR with 95% confidence interval (CI was used as the measure of effect. RESULTS A total of 30.3% of the participants reported experiencing some type of violence (27.6%, psychological; 5.9%, physical; and 7.2%, sexual after the diagnosis of sexually transmitted disease. In the multivariate analysis adjusted to assess intimate partner violence after the revelation of the diagnosis of sexually transmitted diseases, the following variables remained statistically significant: extramarital relations (OR = 3.72; 95%CI 1.91;7.26; p = 0.000, alcohol consumption by the partner (OR = 2.16; 95%CI 1.08;4.33; p = 0.026, history of violence prior to diagnosis (OR = 2.87; 95%CI 1.44;5.69; p = 0.003, and fear of disclosing the diagnosis to the partner (OR = 2.66; 95%CI 1.32;5.32; p = 0.006. CONCLUSIONS Individuals who had extramarital relations, experienced violence prior to the diagnosis of sexually transmitted disease, feared disclosing the diagnosis to the partner, and those whose partner consumed alcohol had an increased likelihood of suffering violence. The high prevalence of intimate partner violence suggests that this population is vulnerable and therefore intervention efforts should be directed to them. Referral health care services for the treatment of sexually transmitted diseases can

  16. Intimate partner violence after the diagnosis of sexually transmitted diseases

    Science.gov (United States)

    Andrade, Roumayne Fernandes Vieira; Araújo, Maria Alix Leite; Vieira, Luiza Jane Eyre de Souza; Reis, Cláudia Bastos Silveira; Miranda, Angélica Espinosa

    2015-01-01

    OBJECTIVE To assess the prevalence and factors associated with intimate partner violence after the diagnosis of sexually transmitted diseases. METHODS This cross-sectional study was conducted in Fortaleza, CE, Northeastern Brazil, in 2012 and involved 221 individuals (40.3% male and 59.7% female) attended to at reference health care units for the treatment of sexually transmitted diseases. Data were collected using a questionnaire applied during interviews with each participant. A multivariate analysis with a logistic regression model was conducted using the stepwise technique. Only the variables with a p value < 0.05 were included in the adjusted analysis. The odds ratio (OR) with 95% confidence interval (CI) was used as the measure of effect. RESULTS A total of 30.3% of the participants reported experiencing some type of violence (27.6%, psychological; 5.9%, physical; and 7.2%, sexual) after the diagnosis of sexually transmitted disease. In the multivariate analysis adjusted to assess intimate partner violence after the revelation of the diagnosis of sexually transmitted diseases, the following variables remained statistically significant: extramarital relations (OR = 3.72; 95%CI 1.91;7.26; p = 0.000), alcohol consumption by the partner (OR = 2.16; 95%CI 1.08;4.33; p = 0.026), history of violence prior to diagnosis (OR = 2.87; 95%CI 1.44;5.69; p = 0.003), and fear of disclosing the diagnosis to the partner (OR = 2.66; 95%CI 1.32;5.32; p = 0.006). CONCLUSIONS Individuals who had extramarital relations, experienced violence prior to the diagnosis of sexually transmitted disease, feared disclosing the diagnosis to the partner, and those whose partner consumed alcohol had an increased likelihood of suffering violence. The high prevalence of intimate partner violence suggests that this population is vulnerable and therefore intervention efforts should be directed to them. Referral health care services for the treatment of sexually transmitted diseases can be strategic

  17. Antimicrobial activity of plant extracts against sexually transmitted pathogens.

    Science.gov (United States)

    Jadhav, Nutan; Kulkarni, Sangeeta; Mane, Arati; Kulkarni, Roshan; Palshetker, Aparna; Singh, Kamalinder; Joshi, Swati; Risbud, Arun; Kulkarni, Smita

    2015-01-01

    Comprehensive management of sexually transmitted infections (STIs) using vaginal or rectal microbicide-based intervention is one of the strategies for prevention of HIV infection. Herbal products have been used for treating STIs traditionally. Herein, we present in vitro activity of 10 plant extracts and their 34 fractions against three sexually transmitted/reproductive tract pathogens - Neisseria gonorrhoeae, Haemophilus ducreyi and Candida albicans. The plant parts were selected; the extracts/fractions were prepared and screened by disc diffusion method. The minimum inhibitory and minimum cidal concentrations were determined. The qualitative phytochemical analysis of selected extracts/fractions showing activity was performed. Of the extracts/fractions tested, three inhibited C. albicans, ten inhibited N. gonorrhoeae and five inhibited H. ducreyi growth. Our study demonstrated that Terminalia paniculata Roth. extracts/fractions inhibited growth of all three organisms. The ethyl acetate fraction of Syzygium cumini Linn. and Bridelia retusa (L.) Spreng. extracts was found to inhibit N. gonorrhoeae at lowest concentrations.

  18. Sexually transmitted diseases: epidemiological and clinical aspects in adults.

    Science.gov (United States)

    Siracusano, Salvatore; Silvestri, Tommaso; Casotto, Daniela

    2014-01-01

    Sexually transmitted diseases (STDs) are the first 10 causes of unpleased diseases in young adult women in the world. The concept of STDs includes a series of syndromes caused by pathogens that can be acquired by sexual intercourse or sexual activity.Adolescents and young adults are responsible for only 25% of the sexually active population and they represent almost 50% of all newly acquired STDs.In this way, we evaluated the epidemiological and clinical aspects of most relevant pathogens as Neisseria gonorrhoeae, Chlamydia trachomatis, Treponema pallidum, Haemophilus Ducreyi, Trichomonas vaginalis, herpes simplex virus, human papilloma virus (HPV) with the exception of hepatitis, and HIV infections for which we suggest specific guidelines.To attain this objective, we analyzed the results of epidemiological and clinical aspects of STDs through a review of the literature using MEDLINE and PubMed database for original articles published using the terms "sexual transmitted disease, epidemiology, diagnosis and therapy" from 2005 to 2014.

  19. Three Dimensional Energy Transmitting Boundary in the Time Domain

    Directory of Open Access Journals (Sweden)

    Naohiro eNakamura

    2015-11-01

    Full Text Available Although the energy transmitting boundary is accurate and efficient for the FEM earthquake response analysis, it could be applied in the frequency domain only. In the previous papers, the author proposed an earthquake response analysis method using the time domain energy transmitting boundary for two dimensional problems. In this paper, this technique is expanded for three dimensional problems. The inner field is supposed to be a hexahedron shape and the approximate time domain boundary is explained, first. Next, two dimensional anti-plane time domain boundary is studied for a part of the approximate three dimensional boundary method. Then, accuracy and efficiency of the proposed method are confirmed by example problems.

  20. Transmitting electric power system dynamics in SCADA using polynomial fitting

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    The paper proposes an approach to transmit electric power system dynamics in the SCADA. With the prevalent application of digital substation automation system, it is feasible for the remote terminal units (RTUs) to collect phasors within a substation. However, limited communication capacity remains the bottleneck that prevents SCADA from transmitting system dynamics. This paper proposes to compress dynamics data with curve fitting in the RTUs and reconstruct the dynamics in the SCADA server for reducing communication demand. Dispatchers in the control center can thus get system dynamics with a delay of several seconds. Simulation result shows that for a power system under disturbance with short-circuit that once occurred and was cleared, the SCADA can approximate the original dynamics with satisfying precision using limited degree polynomial fitting. The approach is highly scalable and adaptable, and can be implemented on existing communication infrastructure with a few software modifications. The approach has extensive application potential.

  1. Spectrally efficient switched transmit diversity for spectrum sharing systems

    KAUST Repository

    Bouida, Zied

    2011-09-01

    Under the scenario of an underlay cognitive radio network, we propose in this paper an adaptive scheme using switched transmit diversity and adaptive modulation in order to increase the spectral efficiency of the secondary link. The proposed bandwidth efficient scheme (BES) uses the scan and wait (SWC) combining technique where a transmission occurs only when a branch with an acceptable performance is found, otherwise data is buffered. In our scheme, the modulation constellation size and the used transmit branch are determined to achieve the highest spectral efficiency given the fading channel conditions, the required error rate performance, and a peak interference constraint to the primary receiver. Selected numerical examples show that the BES scheme increases the capacity of the secondary link when compared to an existing switching efficient scheme (SES). This spectral efficiency comes at the expense of an increased average number of switched branches and thus an increased average delay. © 2011 IEEE.

  2. Joint Transmit Beamforming and Power Control for CDMA System

    Institute of Scientific and Technical Information of China (English)

    LI Ji-long; CHEN Yu; LI Chun-yuan; ZHANG Ping

    2005-01-01

    Downlink transmit beamforming is a promising technique to reduce interference,and power control is a technique to adjust transmission power to satisfy the link quality.Joint transmission power control and beamforming are proposed to minimize total transmission power.The joint optimization problem is solved by receiver beamforming and power control in virtual uplink.SIR based power control is performed to adjust the power allocation,and transmit beamforming weight vectors are determined by Minimum Variance Distortionless Response(MVDR)criterion.The multipath combining weight vectors are determined by maximum ratio combining criterion.Simulation results show the joint optimization scheme decreases the transmission power,and system performance is enhanced.

  3. Canadian Laboratory Standards for Sexually Transmitted Infections: Best Practice Guidelines

    Directory of Open Access Journals (Sweden)

    Max A Chernesky

    2005-01-01

    Full Text Available Sexually transmitted infections (STI continue to spread, and show no international boundaries. Diseases such as gonorrhea and syphilis, which we thought were under control in Canadian populations, have increased in incidence. Sexually transmitted or associated syndromes such as cervicitis, enteric infections, epididymitis, genital ulcers, sexually related hepatitis, ophthalmia neonatorum, pelvic inflammatory disease, prostatitis and vulvovaginitis present a challenge for the physician to identify the microbial cause, treat the patient and manage contacts. During the past 10 years, new technologies developed for the diagnosis of STIs have provided a clearer understanding of the real accuracy of traditional tests for the diagnosis of infections caused by Chlamydia trachomatis, Neisseria gonorrhoeae, Treponema pallidum, herpes simplex viruses, hepatitis B virus, human papillomaviruses, HIV, Haemophilus ducreyi, Trichomonas vaginalis and mycoplasmas. This has presented a major challenge to the diagnostic laboratory, namely, selecting the most sensitive and specific test matched with the most appropriate specimens to provide meaningful and timely results to facilitate optimal patient care.

  4. PAPR Reduction in OFDM Using Partial Transmit Sequence (PTS

    Directory of Open Access Journals (Sweden)

    R.Gayathri

    2013-04-01

    Full Text Available In recent years, OFDM has gained a lot of interest in diverse-digital communication applications. This has been due to its favorable properties like high spectral efficiency and robustness to channel fading. Some of the major drawbacks in OFDM are its high peak-to-average-power ratio(PAPR of the transmitted signals and the synchronization of signals. OFDM consist of large number of independent subcarriers, as a result of which the amplitude of such a signal can have high peak values. Coding, phase rotation and clipping are among many PAPR reduction schemes that have been proposed to overcome this problem. Significant reduction in PAPR has been achieved using Partial Transmit Sequence(PTS which comes under Signal scrambling techniques.

  5. Environmental pollution with soil-transmitted helminths in Sanliurfa, Turkey

    Directory of Open Access Journals (Sweden)

    Ulukanligil Mustafa

    2001-01-01

    Full Text Available Soil transmitted helminth (STH infection are endemic in developing countries. A study was carried out of sewage farms, streams and vegetables to determine the sources and routes of STH infection in Sanliurfa, Turkey. Stool samples from farmhouse inhabitants as well as soil and vegetable samples from the gardens were collected and examined. In addition, water samples from streams and vegetable samples from the city market were collected and examined. One hundred and eighty-seven (59.5% of a total of 314 samples, including 88.4% of the stool samples, 60.8% of the water samples, 84.4% of the soil samples and 14% of the vegetable samples, were found to be positive for STH eggs. These results indicate that the water, soil and vegetables are heavily contaminated, and suggest a vicious circle between humans and the environment. Improving environmental sanitation is imperative for the control of soil-transmitted helminthiasis in Sanliurfa.

  6. Update on strategies of controlling sexually transmitted infections: Taiwan experience

    Directory of Open Access Journals (Sweden)

    Chia-Chun Tsai

    2016-09-01

    Full Text Available Sexually transmitted infections (STIs are a variety of clinical infectious conditions caused by pathogens that are transmitted through sexual activity. In recent years, the incidence of STIs has been gradually rising, according to the statistics of the World Health Organization. Although the recommended management of people who have, or are at risk, for STIs were provided by the association of Europe and the United States, the pathogens of STIs still have a great diversity of epidemiology in different ethnic communities and countries. However, to our knowledge, there have been very few studies updating the status of STIs in the Taiwan population. In this article, we focus on evaluations and announcements for common pathogens of STIs in Taiwan. The strategies for prevention and control of STIs are also discussed in this article. We hope that our experience can be shared to the neighboring countries and lead to an Asian consensus of STI.

  7. Bistatic MIMO Radar Clutter Suppression by Exploiting the Transmit Angle

    Directory of Open Access Journals (Sweden)

    Li Jun

    2014-04-01

    Full Text Available The transmit angle of bistatic radars can be obtained by introducing Multiple-Input Multiple-Output (MIMO radar techniques. The Three-Dimensional (3D clutter spectra, that is, the transmit angle, receive angle, and Doppler frequency, are introduced using the additional angle information to Space-Time Adaptive Processing (STAP. This study reviews the researches on bistatic MIMO-STAP. 3D space-time adaptive processing methods for airborne bistatic side-looking MIMO radars, such as 3D-LCMV, 3D-ACR, 3D-JDL, and 3D projection-based reduced dimensional STAP methods, are discussed. Simulation results show that the proposed methods can improve the small-sample support performance of range-dependent clutter suppression in bistatic side-looking MIMO radar. Finally, the results are summarized and the prospects of bistatic MIMO-STAP are discussed.

  8. Current status of soil-transmitted helminths in Vietnam

    DEFF Research Database (Denmark)

    van der Hoek, Wim; De, Nguyen Van; Konradsen, Flemming

    2003-01-01

    This paper provides a review of surveys on soil-transmitted helminths that were done in Vietnam between 1990 and 2001. Prevalence estimates could be obtained for 29 of the 61 provinces. Extrapolating from this, it is estimated that 33.9 million people in Vietnam are infected with Ascaris (prevale......This paper provides a review of surveys on soil-transmitted helminths that were done in Vietnam between 1990 and 2001. Prevalence estimates could be obtained for 29 of the 61 provinces. Extrapolating from this, it is estimated that 33.9 million people in Vietnam are infected with Ascaris...... is more evenly distributed throughout the country, but is concentrated in peri-urban and rural agricultural areas. Vegetable cultivation in which nightsoil is used as fertilizer is a risk factor for hookworm infection, especially among adult women. Helminth control programs should be targeted at school...

  9. Exploiting Intimate Relationships: Controlling Mosquito-Transmitted Disease with Wolbachia.

    Science.gov (United States)

    Caragata, Eric P; Dutra, Heverton L C; Moreira, Luciano A

    2016-03-01

    Mosquito-transmitted diseases impose a growing burden on human health, and current control strategies have proven insufficient to stem the tide. The bacterium Wolbachia is a novel and promising form of control for mosquito-transmitted disease. It manipulates host biology, restricts infection with dengue and other pathogens, and alters host reproduction to promote rapid spread in the field. In this review, we examine how the intimate and diverse relationships formed between Wolbachia and their mosquito hosts can be exploited for disease control purposes. We consider these relationships in the context of recent developments, including successful field trials with Wolbachia-infected mosquitoes to combat dengue, and new Wolbachia infections in key malaria vectors, which have enhanced the disease control prospects of this unique bacterium. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Design of HTS transmit filter using step impedance resonators

    Energy Technology Data Exchange (ETDEWEB)

    Sekiya, N., E-mail: nsekiya@yamanashi.ac.j [University of Yamanashi, 4-3-11 Takeda, Kofu 400-8511 (Japan); Nakagawa, Y. [University of Yamanashi, 4-3-11 Takeda, Kofu 400-8511 (Japan); Ohshima, S. [Yamagata University, 4-3-16 Johnan, Yonezawa 992-8510 (Japan)

    2010-11-01

    We have designed a high-temperature superconducting (HTS) transmit filter with step impedance resonators (SIRs). A transmit filter using half-wavelength straight-line resonators requires substantial spacing between adjacent resonators. This means that the filter needs a large substrate and that the number of poles is limited. Using SIRs overcomes this problem because SIRs are compact and have weak coupling. An electromagnetic simulator based on the moment method was used to design the SIR filter, which has a center frequency of 5 GHz and a bandwidth of 120 MHz. Simulation showed that it is approximately 19% smaller than a conventional half-wavelength straight-line resonator filter. Additionally, the maximum surface current is approximately 17% less than that of the conventional filter.

  11. Horizontal gene transfer from Agrobacterium to plants

    Directory of Open Access Journals (Sweden)

    Tatiana V. Matveeva

    2014-08-01

    Full Text Available Most genetic engineering of plants uses Agrobacterium mediated transformation to introduce novel gene content. In nature, insertion of T-DNA in the plant genome and its subsequent transfer via sexual reproduction has been shown in several species in the genera Nicotiana and Linaria. In these natural examples of horizontal gene transfer from Agrobacterium to plants, the T-DNA donor is assumed to be a mikimopine strain of A.rhizogenes. A sequence homologous to the T-DNA of the Ri plasmid of Agrobacterium rhizogenes was found in the genome of untransformed Nicotiana glauca about 30 years ago, and was named cellular T-DNA (cT-DNA. It represents an imperfect inverted repeat and contains homologues of several T-DNA oncogenes (NgrolB, NgrolC, NgORF13, NgORF14 and an opine synthesis gene (Ngmis. A similar cT-DNA has also been found in other species of the genus Nicotiana. These presumably ancient homologues of T-DNA genes are still expressed, indicating that they may play a role in the evolution of these plants. Recently T-DNA has been detected and characterized in Linaria vulgaris and L. dalmatica. In Linaria vulgaris the cT-DNA is present in two copies and organized as a tandem imperfect direct repeat, containing LvORF2, LvORF3, LvORF8, LvrolA, LvrolB, LvrolC, LvORF13, LvORF14, and the Lvmis genes. All L. vulgaris and L. dalmatica plants screened contained the same T-DNA oncogenes and the mis gene. Evidence suggests that there were several independent T-DNA integration events into the genomes of these plant genera. We speculate that ancient plants transformed by A. rhizogenes might have acquired a selective advantage in competition with the parental species. Thus, the events of T-DNA insertion in the plant genome might have affected their evolution, resulting in the creation of new plant species. In this review we focus on the structure and functions of cT-DNA in Linaria and Nicotiana and discuss their possible evolutionary role.

  12. Horizontal versus familial transmission of Helicobacter pylori.

    Directory of Open Access Journals (Sweden)

    Sandra Schwarz

    2008-10-01

    Full Text Available Transmission of Helicobacter pylori is thought to occur mainly during childhood, and predominantly within families. However, due to the difficulty of obtaining H. pylori isolates from large population samples and to the extensive genetic diversity between isolates, the transmission and spread of H. pylori remain poorly understood. We studied the genetic relationships of H. pylori isolated from 52 individuals of two large families living in a rural community in South Africa and from 43 individuals of 11 families living in urban settings in the United Kingdom, the United States, Korea, and Colombia. A 3,406 bp multilocus sequence haplotype was determined for a total of 142 H. pylori isolates. Isolates were assigned to biogeographic populations, and recent transmission was measured as the occurrence of non-unique isolates, i.e., isolates whose sequences were identical to those of other isolates. Members of urban families were almost always infected with isolates from the biogeographic population that is common in their location. Non-unique isolates were frequent in urban families, consistent with familial transmission between parents and children or between siblings. In contrast, the diversity of H. pylori in the South African families was much more extensive, and four distinct biogeographic populations circulated in this area. Non-unique isolates were less frequent in South African families, and there was no significant correlation between kinship and similarity of H. pylori sequences. However, individuals who lived in the same household did have an increased probability of carrying the same non-unique isolates of H. pylori, independent of kinship. We conclude that patterns of spread of H. pylori under conditions of high prevalence, such as the rural South African families, differ from those in developed countries. Horizontal transmission occurs frequently between persons who do not belong to a core family, blurring the pattern of familial

  13. A longitudinal examination of sexually transmitted infection/HIV prevention knowledge and sexually transmitted infections among African-American adolescent females.

    Science.gov (United States)

    Voisin, Dexter R; Tan, Kevin; DiClemente, Ralph J

    2013-12-01

    This study examines whether sexually transmitted infection prevention knowledge predicts the acquisition of biologically confirmed sexually transmitted infections among African-American adolescent females. A total of 715 females were recruited from public health clinics in Atlanta, Georgia, and using audio computer-assisted self-interview technology, we assessed for demographics, sexually transmitted infection prevention knowledge, risky sexual behaviors, and sexually transmitted infections. After controlling for demographics and prior risky sexual behaviors, participants with high prevention knowledge were 0.09 times less likely to report sexually transmitted infections, and those with multiple sexual partners were 1.3 times more likely to report sexually transmitted infections. Our findings suggest that the promotion of accurate sexually transmitted prevention knowledge is critical especially among females with multiple sex partners.

  14. How can horizontal wells help in naturally fractured reservoir characterization?

    Energy Technology Data Exchange (ETDEWEB)

    Mazouzi, A.; Deghmoum, A.; Azzouguen, A. [Sonatrach Inc., Hydra (Algeria); Oudjida, A. [Anadarko Inc., (Algeria)

    2000-11-01

    Two successfully drilled horizontal gas wells in the Tin Fouye Tabankort (TFT) fractured reservoir in Algeria were described. The productivity index of horizontal wells compared to vertical wells depends on the pay zone height, vertical anisotropy, lateral anisotropy, the length of the horizontal drain and the amplitude of the damaged zone. Transient tests in horizontal wells can solve the problem of quantifying the vertical and lateral anisotropies. Horizontal wells also minimize the turbulence effects in the vicinity of the wellbore, particularly in gas wells. The two horizontal wells in the TFT reservoir provide an important gas flow rate. The productivity index for each well is triple that of a vertical well. The permeability tensor on the TFT reservoir is established on the basis of transient test reconstitution using numerical simulation. The vertical permeability yields the best match for pressure response. It can be shown as a translation effect in time at the beginning of the linear flow regime. The horizontal anisotropy reacts to the translation of pressure and its derivative in the vertical direction. The configuration of the reservoir shows a high lateral anisotropy with regards to permeability. The vertical permeability can be considered as the composite permeability of both the matrix and fractures. Numerical and laboratory studies show that low permeability is due to fracture opening. Therefore, fracture doesn't necessarily enhance permeability. 8 refs., 3 tabs., 13 figs.

  15. Annual US Air Force Sexually Transmitted Disease (STD) Report, 1995.

    Science.gov (United States)

    1996-05-01

    This report evaluates the 1995 US Air Force (USAF) Sexually Transmitted Diseases ( STD ) Prevention and Control Program. The report analyzes data from...88 medical treatment facilities worldwide and compares 1995 data with that from 1992-94. The 1995 USAF active duty total STD incidence rate was 7.64...cases per 1,000 personnel. This rate represents a 18.9% decline from the 1994 reported STD incidence rate of 9.41 per 1,000 personnel. Among active

  16. Using Piezoelectric Devices to Transmit Power through Walls

    Science.gov (United States)

    Sherrit, Stewart; Bar-Cohen, Yoseph; Bao, Xiaoqi

    2008-01-01

    A method denoted wireless acoustic-electric feed-through (WAEF) has been conceived for transmitting power and/or data signals through walls or other solid objects made of a variety of elastic materials that could be electrically conductive or nonconductive. WAEF would make it unnecessary to use wires, optical fibers, tubes, or other discrete wall-penetrating signal-transmitting components, thereby eliminating the potential for structural weakening or leakage at such penetrations. Avoidance of such penetrations could be essential in some applications in which maintenance of pressure, vacuum, or chemical or biological isolation is required. In a basic WAEF setup, a transmitting piezoelectric transducer on one side of a wall would be driven at resonance to excite ultrasonic vibrations in the wall. A receiving piezoelectric transducer on the opposite side of the wall would convert the vibrations back to an ultrasonic AC electric signal, which would then be detected and otherwise processed in a manner that would depend on the modulation (if any) applied to the signal and whether the signal was used to transmit power, data, or both. An electromechanical-network model has been derived as a computationally efficient means of analyzing and designing a WAEF system. This model is a variant of a prior model, known in the piezoelectric-transducer art as Mason's equivalent-circuit model, in which the electrical and mechanical dynamics, including electromechanical couplings, are expressed as electrical circuit elements that can include inductors, capacitors, and lumped-parameter complex impedances. The real parts of the complex impedances are used to account for dielectric, mechanical, and coupling losses in all components (including all piezoelectric-transducer, wall, and intermediate material layers). In an application to a three-layer piezoelectric structure, this model was shown to yield the same results as do solutions of the wave equations of piezoelectricity and acoustic

  17. Extension of migration velocity analysis to transmitted wavefields

    Science.gov (United States)

    Lameloise, Charles-Antoine; Chauris, Hervé

    2016-10-01

    Migration velocity analysis aims at automatically updating the large-scale components of the velocity model, called macromodel. Extended Common Image Gathers are panels used to evaluate focusing after imaging and are constructed as a function of a spatial shift introduced in the imaging condition. We investigate how transmitted waves can also be used in migration velocity analysis: instead of back-propagating the residuals associated with reflected waves, we propose to back-propagate the full wavefield. The image function, equivalent to the migrated section for reflected data, does not exhibit localized events in space along horizons but is still sensitive to the choice of the background velocity model and can thus be coupled to the same objective function defined in the image domain. In order to enhance the benefits of direct waves, we consider a cross-well configuration. Direct waves provide a large illumination between two vertical wells. Associated Common Image Gathers present different characteristics than the ones associated with reflected waves in surface acquisition. In particular, energy is spread over up to the maximum penetration depth. We invert cross-well seismic data along two lines. In the first case, the input data contain the full wavefield dominated by transmitted waves. It demonstrates the possibility to handle transmitted waves to determine the velocity model. It appears that the misfit in the data domain is largely reduced after inversion. In the second case, we use the same algorithm, but with reflected observed data only, as in a classical approach. Most of velocity updates are localized around the reflectivity, leading to an incorrect final model. This demonstrates the benefit of transmitted waves for migration velocity analysis in a cross-well configuration.

  18. Culex mosquitoes are experimentally unable to transmit Zika virus

    Science.gov (United States)

    Amraoui, Fadila; Atyame-Nten, Célestine; Vega-Rúa, Anubis; Lourenço-de-Oliveira, Ricardo; Vazeille, Marie; Failloux, Anna Bella

    2016-01-01

    We report that two laboratory colonies of Culex quinquefasciatus and Culex pipiens mosquitoes were experimentally unable to transmit ZIKV either up to 21 days post an infectious blood meal or up to 14 days post intrathoracic inoculation. Infectious viral particles were detected in bodies, heads or saliva by a plaque forming unit assay on Vero cells. We therefore consider it unlikely that Culex mosquitoes are involved in the rapid spread of ZIKV. PMID:27605159

  19. Are adolescents being screened for sexually transmitted diseases?

    OpenAIRE

    Ellen, Jonathan M.; Lane, Margo A; McCright, Jacque

    2000-01-01

    Objectives To determine the proportion of sexually experiencedAfrican American adolescents who report having been screened for sexually transmitted diseases and to determine the proportion who report having been screened for these diseases among adolescents who have had a preventive primary health care visit in the past 2 years. Methods A telephone survey of a population-based sample of African American adolescents aged 12 to17 years residing in a low-income neighborhood in San Francisco with...

  20. An Overview of Algorithms for Downlink Transmit Beamforming

    Science.gov (United States)

    2007-11-02

    Swindlehurst Electrical & Computer Engineering Brigham Young University Vector Modulo Pre-coding Use a perturbation of the form SP =,Cc =t(a+ jb) where -c...constellation "spacing" A. Lee Swindlehurst Electrical & Computer Engineering Brigham Young University Vector Modulo Pre-coding (cont.) * Choose c to solve...An Overview of Algorithms for Downlink Transmit Beamforming A. Lee Swindlehurst and Chris Peel Brigham Young University phone: 801-422-4343 email