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Sample records for helmholtz resonator cell

  1. Extraordinary acoustic transmission mediated by Helmholtz resonators

    Directory of Open Access Journals (Sweden)

    Vijay Koju

    2014-07-01

    Full Text Available We demonstrate perfect transmission of sound through a rigid barrier embedded with Helmholtz resonators. The resonators are confined within a waveguide and they are oriented such that one neck protrudes onto each side of the barrier. Perfect sound transmission occurs even though the open area of the necks is less than 3% of the barrier area. Maximum transmission occurs at the resonant frequency of the Helmholtz resonator. Because the dimensions of the Helmholtz resonators are much smaller than the resonant wavelength, the transmission is independent of the direction of sound on the barrier and of the relative placement of the necks. Further, we show that the transmitted sound experiences a continuous phase transition of π radians as a function of frequency through resonance. In simulations of adjacent resonators with slightly offset resonance frequencies, the phase difference leads to destructive interference. By expanding the simulation to a linear array of tuned Helmholtz resonators we show that it is possible to create an acoustic lens. The ability of Helmholtz resonator arrays to manipulate the phase of a plane acoustic wave enables a new class of sonic beam-forming devices analogous to diffractive optics.

  2. Development of a high-sensitivity and portable cell using Helmholtz resonance for noninvasive blood glucose-level measurement based on photoacoustic spectroscopy.

    Science.gov (United States)

    Tachibana, K; Okada, K; Kobayashi, R; Ishihara, Y

    2016-08-01

    We describe the possibility of high-sensitivity noninvasive blood glucose measurement based on photoacoustic spectroscopy (PAS). The demand for noninvasive blood glucose-level measurement has increased due to the explosive increase in diabetic patients. We have developed a noninvasive blood glucose-level measurement based on PAS. The conventional method uses a straight-type resonant cell. However, the cell volume is large, which results in a low detection sensitivity and difficult portability. In this paper, a small-sized Helmholtz-type resonant cell is proposed to improve detection sensitivity and portability by reducing the cell dead volume. First, the acoustic property of the small-sized Helmholtz-type resonant cell was evaluated by performing an experiment using a silicone rubber. As a result, the detection sensitivity of the small-sized Helmholtz-type resonant cell was approximately two times larger than that of the conventional straight-type resonant cell. In addition, the inside volume was approximately 30 times smaller. Second, the detection limits of glucose concentration were estimated by performing an experiment using glucose solutions. The experimental results showed that a glucose concentration of approximately 1% was detected by the small-sized Helmholtz-type resonant cell. Although these results on the sensitivity of blood glucose-level measurement are currently insufficient, they suggest that miniaturization of a resonance cell is effective in the application of noninvasive blood glucose-level measurement.

  3. Experimental realization of extraordinary acoustic transmission using Helmholtz resonators

    Directory of Open Access Journals (Sweden)

    Brian C. Crow

    2015-02-01

    Full Text Available The phenomenon of extraordinary acoustic transmission through a solid barrier with an embedded Helmholtz resonator (HR is demonstrated. The Helmholtz resonator consists of an embedded cavity and two necks that protrude, one on each side of the barrier. Extraordinary transmission occurs for a narrow spectral range encompassing the resonant frequency of the Helmholtz resonator. We show that an amplitude transmission of 97.5% is achieved through a resonator whose neck creates an open area of 6.25% of the total barrier area. In addition to the enhanced transmission, we show that there is a smooth, continuous phase transition in the transmitted sound as a function of frequency. The frequency dependent phase transition is used to experimentally realize slow wave propagation for a narrow-band Gaussian wave packet centered at the maximum transmission frequency. The use of parallel pairs of Helmholtz resonators tuned to different resonant frequencies is experimentally explored as a means of increasing the transmission bandwidth. These experiments show that because of the phase transition, there is always a frequency between the two Helmholtz resonant frequencies at which destructive interference occurs whether the resonances are close or far apart. Finally, we explain how the phase transition associated with Helmholtz-resonator-mediated extraordinary acoustic transmission can be exploited to produce diffractive acoustic components including sub-wavelength thickness acoustic lenses.

  4. Simulation of Helmholtz Resonance Effects in Aircraft ECS

    OpenAIRE

    Pollok, Alexander; Schröffer, Andreas

    2017-01-01

    Helmholtz resonators are closed volumes that are connected to pipes. They exhibit a pronounced resonance frequency, where small boundary pressure excitations in the volume or the environment lead to large mass flow excitations in the pipe. Aircraft have a topology similar to Helmholtz resonators, the closed volume is represented by the cabin, while the pipe is represented by the Environmental Control System. Some discrepancies appear due to the non-zero mass-flow or friction effects in...

  5. Acoustic superlens using Helmholtz-resonator-based metamaterials

    International Nuclear Information System (INIS)

    Yang, Xishan; Yin, Jing; Yu, Gaokun; Peng, Linhui; Wang, Ning

    2015-01-01

    Acoustic superlens provides a way to overcome the diffraction limit with respect to the wavelength of the bulk wave in air. However, the operating frequency range of subwavelength imaging is quite narrow. Here, an acoustic superlens is designed using Helmholtz-resonator-based metamaterials to broaden the bandwidth of super-resolution. An experiment is carried out to verify subwavelength imaging of double slits, the imaging of which can be well resolved in the frequency range from 570 to 650 Hz. Different from previous works based on the Fabry-Pérot resonance, the corresponding mechanism of subwavelength imaging is the Fano resonance, and the strong coupling between the neighbouring Helmholtz resonators separated at the subwavelength interval leads to the enhanced sound transmission over a relatively wide frequency range

  6. Helmholtz resonance in a piezoelectric–hydraulic pump-based hybrid actuator

    International Nuclear Information System (INIS)

    Kim, Gi-Woo; Wang, K W

    2011-01-01

    This paper demonstrates that a hydraulically acting Helmholtz resonator can exist in a piezoelectric–hydraulic pump (PHP) based hybrid actuator, which in turn affects the volumetric efficiency of the PHP. The simulation and experimental results illustrate the effect of Helmholtz resonance on the flow rate performance of the PHP. The study also shows how to shift the Helmholtz resonant frequency to a higher value through changing parameters such as the cylinder diameter and the effective bulk modulus of the working fluid, which will improve the volumetric efficiency and broaden the operating frequency range of the PHP actuator

  7. Noise reduction efficiency of Helmholtz resonator in simulated channel of HVAC system

    Directory of Open Access Journals (Sweden)

    Hossein Ali Yousefi Rizi

    2014-01-01

    Conclusions: This research showed that the designed Helmholtz resonators at a certain frequency of low-frequency sound demonstrated the soundest decrease. The increase in the Helmholtz resonators′ chamber volume and their neck′s pass area are negatively associated with the rate of sound resonance. As a result, of determining the effective frequency range of the Helmholtz resonator, the designed resonator could be applied as an effective and efficient instrument of removing or decreasing noise.

  8. Harvesting energy from airflow with a michromachined piezoelectric harvester inside a Helmholtz resonator

    NARCIS (Netherlands)

    Matova, S.P.; Elfrink, R.; Vullers, R.J.M.; Schaijk, R. van

    2011-01-01

    In this paper we report an airflow energy harvester that combines a piezoelectric energy harvester with a Helmholtz resonator. The resonator converts airflow energy to air oscillations which in turn are converted into electrical energy by a piezoelectric harvester. Two Helmholtz resonators with

  9. Harvesting energy from airflow with a michromachined piezoelectric harvester inside a Helmholtz resonator

    International Nuclear Information System (INIS)

    Matova, S P; Elfrink, R; Vullers, R J M; Van Schaijk, R

    2011-01-01

    In this paper we report an airflow energy harvester that combines a piezoelectric energy harvester with a Helmholtz resonator. The resonator converts airflow energy to air oscillations which in turn are converted into electrical energy by a piezoelectric harvester. Two Helmholtz resonators with adjustable resonance frequencies have been designed—one with a solid bottom and one with membrane on the bottom. The resonance frequencies of the resonators were matched to the complementing piezoelectric harvesters during harvesting. The aim of the presented work is a feasibility study on using packaged piezoelectric energy harvesters with Helmholtz resonators for airflow energy harvesting. The maximum energy we were able to obtain was 42.2 µW at 20 m s −1

  10. A low frequency acoustic insulator by using the acoustic metasurface to a Helmholtz resonator

    Science.gov (United States)

    Zhao, Xiang; Cai, Li; Yu, Dianlong; Lu, Zhimiao; Wen, Jihong

    2017-06-01

    Acoustic metasurfaces (AMSs) are able to manipulate wavefronts at an anomalous angle through a subwavelength layer. Their application provide a new way to control sound waves in addition to traditional materials. In this work, we introduced the AMS into the design of a Helmholtz resonator (HR) and studied the acoustic transmission through the modified HR in a pipe with one branch. The variation of sound insulation capacity with the phase gradient of the AMS was studied, and the results show that the AMS can remarkably lower the frequency band of the sound insulation without increasing the size. Our investigation provides a new degree of freedom for acoustic control with a Helmholtz resonator, which is of great significance in acoustic metasurface theory and sound insulation design.

  11. A low frequency acoustic insulator by using the acoustic metasurface to a Helmholtz resonator

    Directory of Open Access Journals (Sweden)

    Xiang Zhao

    2017-06-01

    Full Text Available Acoustic metasurfaces (AMSs are able to manipulate wavefronts at an anomalous angle through a subwavelength layer. Their application provide a new way to control sound waves in addition to traditional materials. In this work, we introduced the AMS into the design of a Helmholtz resonator (HR and studied the acoustic transmission through the modified HR in a pipe with one branch. The variation of sound insulation capacity with the phase gradient of the AMS was studied, and the results show that the AMS can remarkably lower the frequency band of the sound insulation without increasing the size. Our investigation provides a new degree of freedom for acoustic control with a Helmholtz resonator, which is of great significance in acoustic metasurface theory and sound insulation design.

  12. Increase in effectiveness of low frequency acoustic liners by use of coupled Helmholtz resonators

    Science.gov (United States)

    Dean, L. W.

    1977-01-01

    Coupling of Helmholtz resonators in a low-frequency absorber array was studied as a means for increasing the effectiveness for absorbing low-frequency core engine noise. The equations for the impedance of the coupled-resonator systems were developed in terms of uncoupled-resonator parameters, and the predicted impedance for a parallel-coupled scheme is shown to compare favorably with measurements from a test model. In addition, attenuation measurements made in a flow duct on test coupled-resonator panels are shown to compare favorably with predicted values. Finally, the parallel-coupled concept is shown to give significantly more attenuation than that of a typical uncoupled resonator array of the same total volume.

  13. The Use of Helmholtz Resonance for Measuring the Volume of Liquids and Solids

    Directory of Open Access Journals (Sweden)

    Clive E. Davies

    2010-11-01

    Full Text Available An experimental investigation was undertaken to ascertain the potential of using Helmholtz resonance for volume determination and the factors that may influence accuracy. The uses for a rapid non-interference volume measurement system range from agricultural produce and mineral sampling through to liquid fill measurements. By weighing the sample the density can also measured indirectly.

  14. Preliminary analysis of resonance effect by Helmholtz-Schrödinger method

    International Nuclear Information System (INIS)

    Er-Yan, Yan; Fan-Bao, Meng; Hong-Ge, Ma; Chao-Yang, Chen

    2010-01-01

    The Helmholtz-Schrödinger method is employed to study the electric field standing wave caused by coupling through a simple slot. There is a good agreement between the numerical results and the resonant conditions presented by the Helmholtz—Schrödinger method. Thus, it can be used in similar cases where the amplitude of the electric field is the important quantity or eigenfunctions of the Schrödinger equation are needed for complicated quantum structures with hard wall boundary conditions. (general)

  15. Numerical investigation on an array of Helmholtz resonators for the reduction of micro-pressure waves in modern and future high-speed rail tunnel systems

    Science.gov (United States)

    Tebbutt, J. A.; Vahdati, M.; Carolan, D.; Dear, J. P.

    2017-07-01

    Previous research has proposed that an array of Helmholtz resonators may be an effective method for suppressing the propagation of pressure and sound waves, generated by a high-speed train entering and moving in a tunnel. The array can be used to counteract environmental noise from tunnel portals and also the emergence of a shock wave in the tunnel. The implementation of an array of Helmholtz resonators in current and future high-speed train-tunnel systems is studied. Wave propagation in the tunnel is modelled using a quasi-one-dimensional formulation, accounting for non-linear effects, wall friction and the diffusivity of sound. A multi-objective genetic algorithm is then used to optimise the design of the array, subject to the geometric constraints of a demonstrative tunnel system and the incident wavefront in order to attenuate the propagation of pressure waves. It is shown that an array of Helmholtz resonators can be an effective countermeasure for various tunnel lengths. In addition, the array can be designed to function effectively over a wide operating envelope, ensuring it will still function effectively as train speeds increase into the future.

  16. Acoustic energy harvesting using an electromechanical Helmholtz resonator.

    Science.gov (United States)

    Liu, Fei; Phipps, Alex; Horowitz, Stephen; Ngo, Khai; Cattafesta, Louis; Nishida, Toshikazu; Sheplak, Mark

    2008-04-01

    This paper presents the development of an acoustic energy harvester using an electromechanical Helmholtz resonator (EMHR). The EMHR consists of an orifice, cavity, and a piezoelectric diaphragm. Acoustic energy is converted to mechanical energy when sound incident on the orifice generates an oscillatory pressure in the cavity, which in turns causes the vibration of the diaphragm. The conversion of acoustic energy to electrical energy is achieved via piezoelectric transduction in the diaphragm of the EMHR. Moreover, the diaphragm is coupled with energy reclamation circuitry to increase the efficiency of the energy conversion. Lumped element modeling of the EMHR is used to provide physical insight into the coupled energy domain dynamics governing the energy reclamation process. The feasibility of acoustic energy reclamation using an EMHR is demonstrated in a plane wave tube for two power converter topologies. The first is comprised of only a rectifier, and the second uses a rectifier connected to a flyback converter to improve load matching. Experimental results indicate that approximately 30 mW of output power is harvested for an incident sound pressure level of 160 dB with a flyback converter. Such power level is sufficient to power a variety of low power electronic devices.

  17. Multimode Coupling Theory for Kelvin–Helmholtz Instability in Incompressible Fluid

    International Nuclear Information System (INIS)

    Li-Feng, Wang; Ying-Jun, Li; Wen-Hua, Ye; Zheng-Feng, Fan

    2009-01-01

    A weakly nonlinear model is proposed for multimode Kelvin–Helmholtz instability. The second-order mode coupling formula for Kelvin–Helmholtz instability in two-dimensional incompressible fluid is presented by expanding the perturbation velocity potential to second order. It is found that there is an important resonance in the course of the sum frequency mode coupling but the difference frequency mode coupling does not have. This resonance makes the sum frequency mode coupling process relatively complex. The sum frequency mode coupling is strongly dependent on time especially when the density of the two fluids is adjacent and the difference frequency mode coupling is not

  18. Nonlinear aeroacoustic characterization of Helmholtz resonators with a local-linear neuro-fuzzy network model

    Science.gov (United States)

    Förner, K.; Polifke, W.

    2017-10-01

    The nonlinear acoustic behavior of Helmholtz resonators is characterized by a data-based reduced-order model, which is obtained by a combination of high-resolution CFD simulation and system identification. It is shown that even in the nonlinear regime, a linear model is capable of describing the reflection behavior at a particular amplitude with quantitative accuracy. This observation motivates to choose a local-linear model structure for this study, which consists of a network of parallel linear submodels. A so-called fuzzy-neuron layer distributes the input signal over the linear submodels, depending on the root mean square of the particle velocity at the resonator surface. The resulting model structure is referred to as an local-linear neuro-fuzzy network. System identification techniques are used to estimate the free parameters of this model from training data. The training data are generated by CFD simulations of the resonator, with persistent acoustic excitation over a wide range of frequencies and sound pressure levels. The estimated nonlinear, reduced-order models show good agreement with CFD and experimental data over a wide range of amplitudes for several test cases.

  19. Helmholtz's Kant revisited (Once more). The all-pervasive nature of Helmholtz's struggle with Kant's Anschauung.

    Science.gov (United States)

    De Kock, Liesbet

    2016-04-01

    In this analysis, the classical problem of Hermann von Helmholtz's (1821-1894) Kantianism is explored from a particular vantage point, that to my knowledge, has not received the attention it deserves notwithstanding its possible key role in disentangling Helmholtz's relation to Kant's critical project. More particularly, we will focus on Helmholtz's critical engagement with Kant's concept of intuition [Anschauung] and (the related issue of) his dissatisfaction with Kant's doctrinal dualism. In doing so, it soon becomes clear that both (i) crucially mediated Helmholtz's idiosyncratic appropriation and criticism of (certain aspects of) Kant's critical project, and (ii) can be considered as a common denominator in a variety of issues that are usually addressed separately under the general header of (the problem of) Helmholtz's Kantianism. The perspective offered in this analysis can not only shed interesting new light on some interpretive issues that have become commonplace in discussions on Helmholtz's Kantianism, but also offers a particular way of connecting seemingly unrelated dimensions of Helmholtz's engagement with Kant's critical project (e.g. Helmholtz's views on causality and space). Furthermore, it amounts to the rather surprising conclusion that Helmholtz's most drastic revision of Kant's project pertains to his assumption of free will as a formal condition of experience and knowledge. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Nonlinearity, Viscosity and Air-Compressibility Effects on the Helmholtz Resonant Wave Motion Generated by an Oscillating Twin Body in a Free Surface

    Science.gov (United States)

    Ananthakrishnan, Palaniswamy

    2012-11-01

    The problem is of practical relevance in determining the motion response of multi-hull and air-cushion vehicles in high seas and in littoral waters. The linear inviscid problem without surface pressure has been well studied in the past. In the present work, the nonlinear wave-body interaction problem is solved using finite-difference methods based on boundary-fitted coordinates. The inviscid nonlinear problem is tackled using the mixed Eulerian-Lagrangian formulation and the solution of the incompressible Navier-Stokes equations governing the viscous problem using a fractional-step method. The pressure variation in the air cushion is modeled using the isentropic gas equation pVγ = Constant. Results show that viscosity and free-surface nonlinearity significantly affect the hydrodynamic force and the wave motion at the resonant Helmholtz frequency (at which the primary wave motion is the vertical oscillation of the mean surface in between the bodies). Air compressibility suppresses the Helmholtz oscillation and enhances the wave radiation. Work supported by the ONR under the grant N00014-98-1-0151.

  1. Voluntarism in early psychology: the case of Hermann von Helmholtz.

    Science.gov (United States)

    De Kock, Liesbet

    2014-05-01

    The failure to recognize the programmatic similarity between (post-)Kantian German philosophy and early psychology has impoverished psychology's historical self-understanding to a great extent. This article aims to contribute to recent efforts to overcome the gaps in the historiography of contemporary psychology, which are the result of an empiricist bias. To this end, we present an analysis of the way in which Hermann von Helmholtz's theory of perception resonates with Johann Gottlieb Fichte's Ego-doctrine. It will be argued that this indebtedness is particularly clear when focusing on the foundation of the differential awareness of subject and object in perception. In doing so, the widespread reception of Helmholtz's work as proto-positivist or strictly empiricist is challenged, in favor of the claim that important elements of his theorizing can only be understood properly against the background of Fichte's Ego-doctrine. PsycINFO Database Record (c) 2014 APA, all rights reserved.

  2. Modern solvers for Helmholtz problems

    CERN Document Server

    Tang, Jok; Vuik, Kees

    2017-01-01

    This edited volume offers a state of the art overview of fast and robust solvers for the Helmholtz equation. The book consists of three parts: new developments and analysis in Helmholtz solvers, practical methods and implementations of Helmholtz solvers, and industrial applications. The Helmholtz equation appears in a wide range of science and engineering disciplines in which wave propagation is modeled. Examples are: seismic inversion, ultrasone medical imaging, sonar detection of submarines, waves in harbours and many more. The partial differential equation looks simple but is hard to solve. In order to approximate the solution of the problem numerical methods are needed. First a discretization is done. Various methods can be used: (high order) Finite Difference Method, Finite Element Method, Discontinuous Galerkin Method and Boundary Element Method. The resulting linear system is large, where the size of the problem increases with increasing frequency. Due to higher frequencies the seismic images need to b...

  3. Acoustic response of Helmholtz dampers in the presence of hot grazing flow

    Science.gov (United States)

    Ćosić, B.; Wassmer, D.; Terhaar, S.; Paschereit, C. O.

    2015-01-01

    Thermoacoustic instabilities are high amplitude instabilities of premixed gas turbine combustors. Cooled passive dampers are used to attenuate or suppress these instabilities in the combustion chamber. For the first time, the influence of temperature differences between the grazing flow in the combustor and the cross-flow emanating from the Helmholtz damper is comprehensively investigated in the linear and nonlinear amplitude regime. The flow field inside the resonator and in the vicinity of the neck is measured with high-speed particle image velocimetry for various amplitudes and at different momentum-flux ratios of grazing and purging flow. Seeding is used as a tracer to qualitatively assess the mixing of the grazing and purging flow as well as the ingestion into the neck of the resonator. Experimentally, the acoustic response for various temperature differences between grazing and purging flow is investigated. The multi-microphone method, in combination with two microphones flush-mounted in the resonator volume and two microphones in the plane of the resonator entrance, is used to determine the impedance of the Helmholtz resonator in the linear and nonlinear amplitude regime for various temperatures and different momentum-flux ratios. Additionally, a thermocouple was used to measure the temperature in the neck. The acoustic response and the temperature measurements are used to obtain the virtual neck length and the effective area jump from a detailed impedance model. This model is extended to include the observed acoustic energy dissipation caused by the density gradients at the neck vicinity. A clear correlation between temperature differences and changes of the mass end-correction is confirmed. The capabilities of the impedance model are demonstrated.

  4. Monolithically integrated Helmholtz coils by 3-dimensional printing

    Energy Technology Data Exchange (ETDEWEB)

    Li, Longguang [Department of Electrical Engineering, University of Michigan–Shanghai Jiao Tong University Joint Institute, Shanghai Jiao Tong University, Shanghai 200240 (China); Abedini-Nassab, Roozbeh; Yellen, Benjamin B., E-mail: yellen@duke.edu [Department of Electrical Engineering, University of Michigan–Shanghai Jiao Tong University Joint Institute, Shanghai Jiao Tong University, Shanghai 200240 (China); Department of Mechanical Engineering and Materials Science, Duke University, P.O. Box 90300, Hudson Hall, Durham, North Carolina 27708 (United States)

    2014-06-23

    3D printing technology is of great interest for the monolithic fabrication of integrated systems; however, it is a challenge to introduce metallic components into 3D printed molds to enable broader device functionality. Here, we develop a technique for constructing a multi-axial Helmholtz coil by injecting a eutectic liquid metal Gallium Indium alloy (EGaIn) into helically shaped orthogonal cavities constructed in a 3D printed block. The tri-axial solenoids each carry up to 3.6 A of electrical current and produce magnetic field up to 70 G. Within the central section of the coil, the field variation is less than 1% and is in agreement with theory. The flow rates and critical pressures required to fill the 3D cavities with liquid metal also agree with theoretical predictions and provide scaling trends for filling the 3D printed parts. These monolithically integrated solenoids may find future applications in electronic cell culture platforms, atomic traps, and miniaturized chemical analysis systems based on nuclear magnetic resonance.

  5. Monolithically integrated Helmholtz coils by 3-dimensional printing

    International Nuclear Information System (INIS)

    Li, Longguang; Abedini-Nassab, Roozbeh; Yellen, Benjamin B.

    2014-01-01

    3D printing technology is of great interest for the monolithic fabrication of integrated systems; however, it is a challenge to introduce metallic components into 3D printed molds to enable broader device functionality. Here, we develop a technique for constructing a multi-axial Helmholtz coil by injecting a eutectic liquid metal Gallium Indium alloy (EGaIn) into helically shaped orthogonal cavities constructed in a 3D printed block. The tri-axial solenoids each carry up to 3.6 A of electrical current and produce magnetic field up to 70 G. Within the central section of the coil, the field variation is less than 1% and is in agreement with theory. The flow rates and critical pressures required to fill the 3D cavities with liquid metal also agree with theoretical predictions and provide scaling trends for filling the 3D printed parts. These monolithically integrated solenoids may find future applications in electronic cell culture platforms, atomic traps, and miniaturized chemical analysis systems based on nuclear magnetic resonance.

  6. MODELING OBSERVED DECAY-LESS OSCILLATIONS AS RESONANTLY ENHANCED KELVIN–HELMHOLTZ VORTICES FROM TRANSVERSE MHD WAVES AND THEIR SEISMOLOGICAL APPLICATION

    Energy Technology Data Exchange (ETDEWEB)

    Antolin, P.; De Moortel, I. [School of Mathematics and Statistics, University of St. Andrews, St. Andrews, Fife KY16 9SS (United Kingdom); Van Doorsselaere, T. [Centre for mathematical Plasma Astrophysics, Mathematics Department, KU Leuven, Celestijnenlaan 200B bus 2400, B-3001 Leuven (Belgium); Yokoyama, T., E-mail: patrick.antolin@st-andrews.ac.uk [Department of Earth and Planetary Science, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan)

    2016-10-20

    In the highly structured solar corona, resonant absorption is an unavoidable mechanism of energy transfer from global transverse MHD waves to local azimuthal Alfvén waves. Due to its localized nature, direct detection of this mechanism is extremely difficult. Yet, it is the leading theory explaining the observed fast damping of the global transverse waves. However, at odds with this theoretical prediction are recent observations that indicate that in the low-amplitude regime such transverse MHD waves can also appear decay-less, a still unsolved phenomenon. Recent numerical work has shown that Kelvin–Helmholtz instabilities (KHI) often accompany transverse MHD waves. In this work, we combine 3D MHD simulations and forward modeling to show that for currently achieved spatial resolution and observed small amplitudes, an apparent decay-less oscillation is obtained. This effect results from the combination of periodic brightenings produced by the KHI and the coherent motion of the KHI vortices amplified by resonant absorption. Such an effect is especially clear in emission lines forming at temperatures that capture the boundary dynamics rather than the core, and reflects the low damping character of the local azimuthal Alfvén waves resonantly coupled to the kink mode. Due to phase mixing, the detected period can vary depending on the emission line, with those sensitive to the boundary having shorter periods than those sensitive to the loop core. This allows us to estimate the density contrast at the boundary.

  7. A Weakly Nonlinear Model for Kelvin–Helmholtz Instability in Incompressible Fluids

    International Nuclear Information System (INIS)

    Li-Feng, Wang; Wen-Hua, Ye; Zheng-Feng, Fan; Chuang, Xue; Ying-Jun, Li

    2009-01-01

    A weakly nonlinear model is proposed for the Kelvin–Helmholtz instability in two-dimensional incompressible fluids by expanding the perturbation velocity potential to third order. The third-order harmonic generation effects of single-mode perturbation are analyzed, as well as the nonlinear correction to the exponential growth of the fundamental modulation. The weakly nonlinear results are supported by numerical simulations. Density and resonance effects exist in the development of mode coupling. (fundamental areas of phenomenology (including applications))

  8. Kelvin-Helmholtz instability in solar spicules

    Directory of Open Access Journals (Sweden)

    H Ebadi

    2016-12-01

    Full Text Available Magneto hydrodynamic waves, propagating along spicules, may become unstable and the expected instability is of Kelvin-Helmholtz type. Such instability can trigger the onset of wave turbulence leading to an effective plasma heating and particle acceleration. In present study, two-dimensional magneto hydrodynamic simulations performed on a Cartesian grid is presented in spicules with different densities, moving at various speeds depending on their environment. Simulations being applied in this study show the onset of Kelvin-Helmholtz type instability and transition to turbulent flow in spicules. Development of Kelvin-Helmholtz instability leads to momentum and energy transport, dissipation, and mixing of fluids. When magnetic fields are involved, field amplification is also possible to take place

  9. The research reactor BER II at the Helmholtz-Center Berlin

    Energy Technology Data Exchange (ETDEWEB)

    Krohn, Herbert [Helmholtz-Zentrum Berlin (HZB), Berlin (Germany)

    2012-10-15

    For basic and application-oriented research assignments the Helmholtz-Center Berlin (Helmholtz Zentrum Berlin - HZB) runs a research reactor that operates as a source of neutron beams for a wide range of scientific investigations. At the end of the 1980{sup th} the BER II was completed renewed and fitted with new experimental facilities. The BER II is a light water cooled and moderated swimming pool type reactor to be operated at 10 MW thermal power. Six neutron guides deliver cold neutrons from the cold moderator cell to a neutron guide hall adjacent to the experiment hall. With its 24 experimental stations, experimenters at HZB have practically all neutron scattering or neutron radiography techniques at their disposal. (orig.)

  10. The research reactor BER II at the Helmholtz-Center Berlin

    International Nuclear Information System (INIS)

    Krohn, Herbert

    2012-01-01

    For basic and application-oriented research assignments the Helmholtz-Center Berlin (Helmholtz Zentrum Berlin - HZB) runs a research reactor that operates as a source of neutron beams for a wide range of scientific investigations. At the end of the 1980 th the BER II was completed renewed and fitted with new experimental facilities. The BER II is a light water cooled and moderated swimming pool type reactor to be operated at 10 MW thermal power. Six neutron guides deliver cold neutrons from the cold moderator cell to a neutron guide hall adjacent to the experiment hall. With its 24 experimental stations, experimenters at HZB have practically all neutron scattering or neutron radiography techniques at their disposal. (orig.)

  11. Electron Debye scale Kelvin-Helmholtz instability: Electrostatic particle-in-cell simulations

    International Nuclear Information System (INIS)

    Lee, Sang-Yun; Lee, Ensang; Kim, Khan-Hyuk; Lee, Dong-Hun; Seon, Jongho; Jin, Ho

    2015-01-01

    In this paper, we investigated the electron Debye scale Kelvin-Helmholtz (KH) instability using two-dimensional electrostatic particle-in-cell simulations. We introduced a velocity shear layer with a thickness comparable to the electron Debye length and examined the generation of the KH instability. The KH instability occurs in a similar manner as observed in the KH instabilities in fluid or ion scales producing surface waves and rolled-up vortices. The strength and growth rate of the electron Debye scale KH instability is affected by the structure of the velocity shear layer. The strength depends on the magnitude of the velocity and the growth rate on the velocity gradient of the shear layer. However, the development of the electron Debye scale KH instability is mainly determined by the electric field generated by charge separation. Significant mixing of electrons occurs across the shear layer, and a fraction of electrons can penetrate deeply into the opposite side fairly far from the vortices across the shear layer

  12. Helmholtz and the psychophysiology of time.

    Science.gov (United States)

    Debru, C

    2001-09-01

    After having measured the velocity of the nervous impulse in the 1850s, Helmholtz began doing research on the temporal dimensions of visual perception. Experiments dealing with the velocity of propagation in nerves (as well as with aspects of perception) were carried out occasionally for some fifteen years until their final publication in 1871. Although the temporal dimension of perception seems to have interested Helmholtz less than problems of geometry and space, his experiments on the time of perception were technically rather subtle and seminal, especially compared with experiments performed by his contemporaries, such as Sigmund Exner, William James, Rudolf Hermann Lotze, Ernst Mach, Wilhelm Volkmann, and Wilhelm Wundt. Helmholtz's conception of the temporal aspects of perception reflects the continuity that holds between psychophysiological research and the Kantian philosophical background.

  13. Transmission loss of double wall panels containing Helmholtz resonators

    Science.gov (United States)

    Prydz, R. A.; Kuntz, H. L.; Morrow, D. L.; Wirt, L. S.

    Data and an analysis are presented on the use of Helholtz resonators in double wall panels (i.e., aircraft sidewalls). Several wall materials and resonator configurations were tested, and the resonators were found to substantially increase the transmission loss of the double wall system at the tuning frequency.

  14. Novel Hyperbolic Homoclinic Solutions of the Helmholtz-Duffing Oscillators

    Directory of Open Access Journals (Sweden)

    Yang-Yang Chen

    2016-01-01

    Full Text Available The exact and explicit homoclinic solution of the undamped Helmholtz-Duffing oscillator is derived by a presented hyperbolic function balance procedure. The homoclinic solution of the self-excited Helmholtz-Duffing oscillator can also be obtained by an extended hyperbolic perturbation method. The application of the present homoclinic solutions to the chaos prediction of the nonautonomous Helmholtz-Duffing oscillator is performed. Effectiveness and advantage of the present solutions are shown by comparisons.

  15. Magnetohydrodynamic Kelvin-Helmholtz instability; Magnetohydrodynamische Kelvin-Helmholtz-Instabilitaet

    Energy Technology Data Exchange (ETDEWEB)

    Brett, Walter

    2014-07-21

    In the presented work the Kelvin-Helmholtz-Instability in magnetohydrodynamic flows is analyzed with the methods of Multiple Scales. The concerned fluids are incompressible or have a varying density perpendicular to the vortex sheet, which is taken into account using a Boussinesq-Approximation and constant Brunt-Vaeisaelae-Frequencies. The Multiple Scale Analysis leads to nonlinear evolution equations for the amplitude of the perturbations. Special solutions to these equations are presented and the effects of the magnetic fields are discussed.

  16. Zero Quantum Nuclear Magnetic Resonance experiments utilizing a toroid cell and coil

    OpenAIRE

    Bebout, William Roach

    1989-01-01

    Over the past ten to fifteen years the area of Nuclear Magnetic Resonance (NMR) Spectroscopy has seen tremendous growth. For example, in conjunction with multiple quantum NMR, molecular structural mapping of a compound can be easily performed in a two dimensional (2D) experiment. However, only two kinds of detector coils have been typically used in NMR studies. These are the solenoid coil and the Helmholtz coil. The solenoid coil was very popular with the permanent and e...

  17. Helmholtz bright and boundary solitons

    International Nuclear Information System (INIS)

    Christian, J M; McDonald, G S; Chamorro-Posada, P

    2007-01-01

    We report, for the first time, exact analytical boundary solitons of a generalized cubic-quintic nonlinear Helmholtz (NLH) equation. These solutions have a linked-plateau topology that is distinct from conventional dark soliton solutions; their amplitude and intensity distributions are spatially delocalized and connect regions of finite and zero wave-field disturbances (suggesting also the classification as 'edge solitons'). Extensive numerical simulations compare the stability properties of recently derived Helmholtz bright solitons, for this type of polynomial nonlinearity, to those of the new boundary solitons. The latter are found to possess a remarkable stability characteristic, exhibiting robustness against perturbations that would otherwise lead to the destabilizing of their bright-soliton counterparts

  18. Helmholtz bright and boundary solitons

    Energy Technology Data Exchange (ETDEWEB)

    Christian, J M [Joule Physics Laboratory, School of Computing, Science and Engineering, Institute for Materials Research, University of Salford, Salford M5 4WT (United Kingdom); McDonald, G S [Joule Physics Laboratory, School of Computing, Science and Engineering, Institute for Materials Research, University of Salford, Salford M5 4WT (United Kingdom); Chamorro-Posada, P [Departmento de TeorIa de la Senal y Comunicaciones e IngenierIa Telematica, Universidad de Valladolid, ETSI Telecomunicacion, Campus Miguel Delibes s/n, 47011 Valladolid (Spain)

    2007-02-16

    We report, for the first time, exact analytical boundary solitons of a generalized cubic-quintic nonlinear Helmholtz (NLH) equation. These solutions have a linked-plateau topology that is distinct from conventional dark soliton solutions; their amplitude and intensity distributions are spatially delocalized and connect regions of finite and zero wave-field disturbances (suggesting also the classification as 'edge solitons'). Extensive numerical simulations compare the stability properties of recently derived Helmholtz bright solitons, for this type of polynomial nonlinearity, to those of the new boundary solitons. The latter are found to possess a remarkable stability characteristic, exhibiting robustness against perturbations that would otherwise lead to the destabilizing of their bright-soliton counterparts.

  19. An implicit finite-difference operator for the Helmholtz equation

    KAUST Repository

    Chu, Chunlei; Stoffa, Paul L.

    2012-01-01

    We have developed an implicit finite-difference operator for the Laplacian and applied it to solving the Helmholtz equation for computing the seismic responses in the frequency domain. This implicit operator can greatly improve the accuracy of the simulation results without adding significant extra computational cost, compared with the corresponding conventional explicit finite-difference scheme. We achieved this by taking advantage of the inherently implicit nature of the Helmholtz equation and merging together the two linear systems: one from the implicit finite-difference discretization of the Laplacian and the other from the discretization of the Helmholtz equation itself. The end result of this simple yet important merging manipulation is a single linear system, similar to the one resulting from the conventional explicit finite-difference discretizations, without involving any differentiation matrix inversions. We analyzed grid dispersions of the discrete Helmholtz equation to show the accuracy of this implicit finite-difference operator and used two numerical examples to demonstrate its efficiency. Our method can be extended to solve other frequency domain wave simulation problems straightforwardly. © 2012 Society of Exploration Geophysicists.

  20. An implicit finite-difference operator for the Helmholtz equation

    KAUST Repository

    Chu, Chunlei

    2012-07-01

    We have developed an implicit finite-difference operator for the Laplacian and applied it to solving the Helmholtz equation for computing the seismic responses in the frequency domain. This implicit operator can greatly improve the accuracy of the simulation results without adding significant extra computational cost, compared with the corresponding conventional explicit finite-difference scheme. We achieved this by taking advantage of the inherently implicit nature of the Helmholtz equation and merging together the two linear systems: one from the implicit finite-difference discretization of the Laplacian and the other from the discretization of the Helmholtz equation itself. The end result of this simple yet important merging manipulation is a single linear system, similar to the one resulting from the conventional explicit finite-difference discretizations, without involving any differentiation matrix inversions. We analyzed grid dispersions of the discrete Helmholtz equation to show the accuracy of this implicit finite-difference operator and used two numerical examples to demonstrate its efficiency. Our method can be extended to solve other frequency domain wave simulation problems straightforwardly. © 2012 Society of Exploration Geophysicists.

  1. Kelvin-Helmholtz instability as a possible cause of edge localized modes

    International Nuclear Information System (INIS)

    Strauss, H.R.

    1992-01-01

    Edge localized modes may be a Kelvin-Helmholtz instability caused by the sheared rotation of H-mode plasmas. The Kelvin-Helmholtz instability is stabilized by coupling to Alfven waves. There is a critical velocity gradient, of the order of the Alfven velocity divided by the magnetic shear length. This is verified in a numerical simulation. The critical velocity shear is consistent with experiment. A non-linear simulation shows how the Kelvin-Helmholtz mode can cause oscillations of the velocity profile. (author). Letter-to-the-editor. 13 refs, 6 figs

  2. Interference-induced angle-independent acoustical transparency

    International Nuclear Information System (INIS)

    Qi, Lehua; Yu, Gaokun; Wang, Ning; Wang, Xinlong; Wang, Guibo

    2014-01-01

    It is revealed that the Fano-like interference leads to the extraordinary acoustic transmission through a slab metamaterial of thickness much smaller than the wavelength, with each unit cell consisting of a Helmholtz resonator and a narrow subwavelength slit. More importantly, both the theoretical analysis and experimental measurement show that the angle-independent acoustical transparency can be realized by grafting a Helmholtz resonator and a quarter-wave resonator to the wall of a narrow subwavelength slit in each unit cell of a slit array. The observed phenomenon results from the interferences between the waves propagating in the slit, those re-radiated by the Helmholtz resonator, and those re-radiated by the quarter-wave resonator. The proposed design may find its applications in designing angle-independent acoustical filters and controlling the phase of the transmitted waves

  3. Helmholtz solitons in power-law optical materials

    International Nuclear Information System (INIS)

    Christian, J. M.; McDonald, G. S.; Potton, R. J.; Chamorro-Posada, P.

    2007-01-01

    A nonlinear Helmholtz equation for optical materials with regimes of power-law type of nonlinearity is proposed. This model captures the evolution of broad beams at any angle with respect to the reference direction in a wide range of media, including some semiconductors, doped glasses, and liquid crystals. Exact analytical soliton solutions are presented for a generic nonlinearity, within which known Kerr solitons comprise a subset. Three general conservation laws are also reported. Analysis and numerical simulations examine the stability of the Helmholtz power-law solitons. A propagation feature, associated with spatial solitons in power-law media, constituting a class of oscillatory solution, is identified

  4. Bistable Helmholtz solitons in cubic-quintic materials

    International Nuclear Information System (INIS)

    Christian, J. M.; McDonald, G. S.; Chamorro-Posada, P.

    2007-01-01

    We propose a nonlinear Helmholtz equation for modeling the evolution of broad optical beams in media with a cubic-quintic intensity-dependent refractive index. This type of nonlinearity is appropriate for some semiconductor materials, glasses, and polymers. Exact analytical soliton solutions are presented that describe self-trapped nonparaxial beams propagating at any angle with respect to the reference direction. These spatially symmetric solutions are, to the best of our knowledge, the first bistable Helmholtz solitons to be derived. Accompanying conservation laws (both integral and particular forms) are also reported. Numerical simulations investigate the stability of the solitons, which appear to be remarkably robust against perturbations

  5. On Helmholtz Problem for Plane Periodical Structures

    International Nuclear Information System (INIS)

    Akishin, P.G.; Vinitskij, S.I.

    1994-01-01

    The plane Helmholtz problem of the periodical disc structures with the phase shifts conditions of the solutions along the basis lattice vectors and the Dirichlet conditions on the basic boundaries is considered. The Green function satisfying the quasi periodical conditions on the lattice is constructed. The Helmholtz problem is reduced to the boundary integral equations for the simple layer potentials of this Green function. The methods of the discretization of the arising integral equations are proposed. The procedures of calculation of the matrix elements are discussed. The reality of the spectral parameter of the nonlinear continuous and discretized problems is shown. 8 refs., 2 figs

  6. Bistable dark solitons of a cubic-quintic Helmholtz equation

    International Nuclear Information System (INIS)

    Christian, J. M.; McDonald, G. S.; Chamorro-Posada, P.

    2010-01-01

    We provide a report on exact analytical bistable dark spatial solitons of a nonlinear Helmholtz equation with a cubic-quintic refractive-index model. Our analysis begins with an investigation of the modulational instability characteristics of Helmholtz plane waves. We then derive a dark soliton by mapping the desired asymptotic form onto a uniform background field and obtain a more general solution by deploying rotational invariance laws in the laboratory frame. The geometry of the new soliton is explored in detail, and a range of new physical predictions is uncovered. Particular attention is paid to the unified phenomena of arbitrary-angle off-axis propagation and nondegenerate bistability. Crucially, the corresponding solution of paraxial theory emerges in a simultaneous multiple limit. We conclude with a set of computer simulations that examine the role of Helmholtz dark solitons as robust attractors.

  7. Helmholtz and Zoellner: nineteenth-century empiricism, spiritism, and the theory of space perception.

    Science.gov (United States)

    Stromberg, W H

    1989-10-01

    J. K. F. Zoellner began writing on "experimental proofs" of a fourth spatial dimension, and of the existence of spirits, in 1878. His arguments caused strong controversy, with rebuttal essays by Wilhelm Wundt and others. The author argues that Zoellner's case that these matters are experimental questions rested on arguments which Hermann von Helmholtz, inveighing against rationalist views of space and space perception, had recently published. Zoellner's use of Helmholtz's arguments to advance and defend his spiritist views occasioned strong criticism of Helmholtz, affected careers and reputations of scholars in Berlin and Leipzig, and caused enduring controversy over the credibility of Helmholtz's empiricist theory of space perception.

  8. Resonance in a Cone-Topped Tube

    Directory of Open Access Journals (Sweden)

    Angus Cheng-Huan Chia

    2011-06-01

    Full Text Available The relationship between ratio of the upper opening diameter of a cone-topped cylinder to the cylinder diameter,and the ratio of the length of the air column to resonant period was examined. Plastic cones with upper openings ranging from 1.3 cm to 3.6 cm and tuning forks with frequencies ranging from 261.6 Hz to 523.3 Hz were used. The transition from a standing wave in a cylindrical column to a Helmholtz-type resonance in a resonant cavity with a narrow opening was observed.

  9. A model for precalculus students to determine the resonance frequency of a trumpet mouthpiece

    Science.gov (United States)

    Chapman, Robert C.

    2004-05-01

    The trumpet mouthpiece as a Helmholtz resonator is used to show precalculus students a mathematical model for determining the approximate resonance frequency of the mouthpiece. The mathematics is limited to algebra and trigonometry. Using a system of mouthpieces that have interchangeable cups and backbores, students are introduced to the acoustics of this resonator. By gathering data on 51 different configurations of mouthpieces, the author modifies the existing Helmholtz resonator equation to account for both cup volumes and backbore configurations. Students then use this model for frequency predictions. Included are how to measure the different physical attributes of a trumpet mouthpiece at minimal cost. This includes methods for measuring cup volume, backbore volume, backbore length, throat area, etc. A portion of this phase is de-signed for students to become acquainted with some of the vocabulary of acoustics and the physics of sound.

  10. Resonant freak microwaves

    International Nuclear Information System (INIS)

    Aguiar, F.M. de

    2011-01-01

    The Helmholtz equation describing transverse magnetic modes in a closed flat microwave resonator with 60 randomly distributed discs is numerically solved. At lower frequencies, the calculated wave intensity spatially distributed obeys the universal Porter-Thomas form if localized modes are excluded. A superposition of resonant modes is shown to lead to rare events of extreme intensities (freak waves) at localized 'hot spots'. The temporally distributed intensity of such a superposition at the center of a hot spot also follows the Porter-Thomas form. Branched modes are found at higher frequencies. The results bear resemblance to recent experiments reported in an open cavity.

  11. Symmetry-breaking analysis for the general Helmholtz-Duffing oscillator

    International Nuclear Information System (INIS)

    Cao Hongjun; Seoane, Jesus M.; Sanjuan, Miguel A.F.

    2007-01-01

    The symmetry breaking phenomenon for a general Helmholtz-Duffing oscillator as a function of a symmetric parameter in the nonlinear force is investigated. Different values of this parameter convert the general oscillator into either the Helmholtz or the Duffing oscillator. Due to the variation of the symmetric parameter, the phase space patterns of the unperturbed Helmholtz-Duffing oscillator will cause a huge difference between the left-hand homoclinic orbit and the right-hand one. In particular, the area of the left-hand homoclinic orbits is a strictly monotonously decreasing function, while the area of the right-hand homoclinic orbit varies only in a very small range. There exist distinct local supercritical and subcritical saddle-node bifurcations at two different centers. The left-hand and the right-hand existing regions of the harmonic solutions of the Helmholtz-Duffing oscillator created by the left-hand and the right-hand saddle-node bifurcation curves will lead to different transition in the amplitude-frequency plane. There exists also a critical frequency which has the effect that the left-hand homoclinic bifurcation value is equal to the right-hand homoclinic bifurcation value. And, if the amplitude coefficient of the Helmholtz-Duffing oscillator is used as the control parameter, and it is larger than the same left-hand and right-hand homoclinic bifurcation, then the global stability of the system will be destroyed at a lowest cost. Besides this critical frequency, the left-hand and the right-hand homoclinic bifurcations are not only unequal, but also their effects for the system's stability are different. Among them, the effect resulting from the small homoclinic bifurcation for the system's stability is local and negligible, while the effect from the large homoclinic bifurcation is global but this is accomplished at a quite larger cost

  12. The Determinate World Kant and Helmholtz on the Physical Meaning of Geometry

    CERN Document Server

    Hyder, David

    2009-01-01

    This study examines the place of Hermann von Helmholtz´s seminal papers on geometry in his philosophy of science. The arguments of these papers are traced back to his prior work on the theory of magnitudes, as well as to Helmholtz´s early, Kantian position. The author claims that Helmholtz should be understood not as opposing Kant, but as modifying the latter´s theory of magnitudes so as to remove obstacles to their common project of constructing a complete system of natural science.

  13. Helmholtz algebraic solitons

    Energy Technology Data Exchange (ETDEWEB)

    Christian, J M; McDonald, G S [Joule Physics Laboratory, School of Computing, Science and Engineering, Materials and Physics Research Centre, University of Salford, Salford M5 4WT (United Kingdom); Chamorro-Posada, P, E-mail: j.christian@salford.ac.u [Departamento de Teoria de la Senal y Comunicaciones e Ingenieria Telematica, Universidad de Valladolid, ETSI Telecomunicacion, Campus Miguel Delibes s/n, 47011 Valladolid (Spain)

    2010-02-26

    We report, to the best of our knowledge, the first exact analytical algebraic solitons of a generalized cubic-quintic Helmholtz equation. This class of governing equation plays a key role in photonics modelling, allowing a full description of the propagation and interaction of broad scalar beams. New conservation laws are presented, and the recovery of paraxial results is discussed in detail. The stability properties of the new solitons are investigated by combining semi-analytical methods and computer simulations. In particular, new general stability regimes are reported for algebraic bright solitons.

  14. Helmholtz algebraic solitons

    International Nuclear Information System (INIS)

    Christian, J M; McDonald, G S; Chamorro-Posada, P

    2010-01-01

    We report, to the best of our knowledge, the first exact analytical algebraic solitons of a generalized cubic-quintic Helmholtz equation. This class of governing equation plays a key role in photonics modelling, allowing a full description of the propagation and interaction of broad scalar beams. New conservation laws are presented, and the recovery of paraxial results is discussed in detail. The stability properties of the new solitons are investigated by combining semi-analytical methods and computer simulations. In particular, new general stability regimes are reported for algebraic bright solitons.

  15. Solving the Helmholtz equation in conformal mapped ARROWstructures using homotopy perturbation method

    DEFF Research Database (Denmark)

    Reck, Kasper; Thomsen, Erik Vilain; Hansen, Ole

    2011-01-01

    . The solution of the mapped Helmholtz equation is found by solving an infinite series of Poisson equations using two dimensional Fourier series. The solution is entirely based on analytical expressions and is not mesh dependent. The analytical results are compared to a numerical (finite element method) solution......The scalar wave equation, or Helmholtz equation, describes within a certain approximation the electromagnetic field distribution in a given system. In this paper we show how to solve the Helmholtz equation in complex geometries using conformal mapping and the homotopy perturbation method...

  16. Transmission problems for the Helmholtz equation for a rectilinear-circular lune

    Directory of Open Access Journals (Sweden)

    Volodymyr Denysenko

    2007-01-01

    Full Text Available The question related to the construction of the solution of plane transmission problem for the Helmholtz equation in a rectilinear-circular lune is considered. An approach is proposed based on the method of partial domains and the principle of reflection for the solutions of the Helmholtz equation through the segment.

  17. The Helmholtz legacy in physiological acoustics

    CERN Document Server

    Hiebert, Erwin

    2014-01-01

    This book explores the interactions between science and music in the late nineteenth- and early twentieth century. It examines and evaluates the work of Hermann von Helmholtz, Max Planck, Shohe Tanaka, and Adriaan Fokker, leading physicists and physiologists who were committed to understanding crucial aesthetic components of the art of music, including the standardization of pitch and the implementation of various types of intonations. With a mixture of physics, physiology, and aesthetics, author Erwin Hiebert addresses throughout the book how just intonation came to intersect with the history of keyboard instruments and exert an influence on the development of Western music. He begins with the work of Hermann von Helmholtz, a leading nineteenth-century physicist and physiologist who not only made important contributions in vision, optics, electrodynamics and thermodynamics, but also helped advanced the field of music theory as well. The author traces the Helmholtzian trends of thought that become inherently ...

  18. The Helmholtz Hierarchy: Phase Space Statistics of Cold Dark Matter

    OpenAIRE

    Tassev, Svetlin

    2010-01-01

    We present a new formalism to study large-scale structure in the universe. The result is a hierarchy (which we call the "Helmholtz Hierarchy") of equations describing the phase space statistics of cold dark matter (CDM). The hierarchy features a physical ordering parameter which interpolates between the Zel'dovich approximation and fully-fledged gravitational interactions. The results incorporate the effects of stream crossing. We show that the Helmholtz hierarchy is self-consistent and obeys...

  19. Observation of Motion of Bowed Strings and Resonant Strings in Violin Performances

    Science.gov (United States)

    Matsutani, Akihiro

    2013-10-01

    The motion of a bowed string and a resonant string of a violin were simultaneously observed for the first time. The results of the direct observation of string motion in double stops and harmonics are also presented. The importance of the resonance was experimentally demonstrated from these observations. It is suggested that players should take account of the resonance and ideal Helmholtz motion in violin performances.

  20. Magnetohydrodynamic Kelvin-Helmholtz instabilities in astrophysics. 2. Cylindrical boundary layer in vortex sheet approximation

    Energy Technology Data Exchange (ETDEWEB)

    Ferrari, A [Max-Planck-Institut fuer Extraterrestrische Physik, Garching b. Muenchen (Germany, F.R.); Consiglio Nazionale delle Ricerche, Turin (Italy). Lab. di Cosmo-Geofisica); Trussoni, E; Zaninetti, L [Consiglio Nazionale delle Ricerche, Turin (Italy). Lab. di Cosmo-Geofisica

    1981-09-01

    This second paper of the series is devoted to Kelvin-Helmholtz instabilities in cylindrical boundary layer flows (jets). The vortex-sheet approximation is still used, and compressible flows are studied in subsonic, transonic, supersonic and relativistic regimes. Magnetic field effects are analysed, together with density contrast inside and outside the jet. The general result is that, due to the onset of a so-called reflection branch of resonant modes, jets are always unstable, both to pinching and helical perturbations with wavelengths of the order of the jet circumference. In particular the time-scales for instability are such that this certainly plays a significant part in the morphology and energetics of extended radio sources.

  1. Thin-Layer Solutions of the Helmholtz and Related Equations

    KAUST Repository

    Ockendon, J. R.

    2012-01-01

    This paper concerns a certain class of two-dimensional solutions to four generic partial differential equations-the Helmholtz, modified Helmholtz, and convection-diffusion equations, and the heat conduction equation in the frequency domain-and the connections between these equations for this particular class of solutions.S pecifically, we consider thin-layer solutions, valid in narrow regions across which there is rapid variation, in the singularly perturbed limit as the coefficient of the Laplacian tends to zero.F or the wellstudied Helmholtz equation, this is the high-frequency limit and the solutions in question underpin the conventional ray theory/WKB approach in that they provide descriptions valid in some of the regions where these classical techniques fail.E xamples are caustics, shadow boundaries, whispering gallery, and creeping waves and focusing and bouncing ball modes.It transpires that virtually all such thin-layer models reduce to a class of generalized parabolic wave equations, of which the heat conduction equation is a special case. Moreover, in most situations, we will find that the appropriate parabolic wave equation solutions can be derived as limits of exact solutions of the Helmholtz equation.W e also show how reasonably well-understood thin-layer phenomena associated with any one of the four generic equations may translate into less well-known effects associated with the others.In addition, our considerations also shed some light on the relationship between the methods of matched asymptotic, WKB, and multiple-scales expansions. © 2012 Society for Industrial and Applied Mathematics.

  2. Another Look at Helmholtz's Model for the Gravitational Contraction of the Sun

    Science.gov (United States)

    Tort, A. C.; Nogarol, F.

    2011-01-01

    We take another look at the Helmholtz model for the gravitational contraction of the Sun. We show that there are two other pedagogically useful ways of rederiving Helmholtz's main results that make use of Gauss's law, the concept of gravitational field energy and the work-kinetic energy theorem. An account of the energy balance involved in the…

  3. From Helmholtz to Schlick: The evolution of the sign-theory of perception.

    Science.gov (United States)

    Oberdan, Thomas

    2015-08-01

    Efforts to trace the influence of fin de siècle neo-Kantianism on early 20th Century philosophy of science have led scholars to recognize the powerful influence on Moritz Schlick of Hermann von Helmholtz, the doyen of 19th Century physics and a leader of the zurȕck zu Kant movement. But Michael Friedman thinks that Schlick misunderstood Helmholtz' signature philosophical doctrine, the sign-theory of perception. Indeed, Friedman has argued that Schlick transformed Helmholtz' Kantian view of spatial intuition into an empiricist version of the causal theory of perception. However, it will be argued that, despite the key role the sign-theory played in his epistemology, Schlick thought the Kantianism in Helmholtz' thought was deeply flawed, rendered obsolete by philosophical insights which emerged from recent scientific developments. So even though Schlick embraced the sign-theory, he rejected Helmholtz' ideas about spatial intuition. In fact, like his teacher, Max Planck, Schlick generalized the sign-theory into a form of structural realism. At the same time, Schlick borrowed the method of concept-formation developed by the formalist mathematicians, Moritz Pasch and David Hilbert, and combined it with the conventionalism of Henri Poincaré. Then, to link formally defined concepts with experience, Schlick's introduced his 'method of coincidences', similar to the 'point-coincidences' featured in Einstein's physics. The result was an original scientific philosophy, which owed much to contemporary scientific thinkers, but little to Kant or Kantianism. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. Riemann's and Helmholtz-Lie's problems of space from Weyl's relativistic perspective

    Science.gov (United States)

    Bernard, Julien

    2018-02-01

    I reconstruct Riemann's and Helmholtz-Lie's problems of space, from some perspectives that allow for a fruitful comparison with Weyl. In Part II. of his inaugural lecture, Riemann justifies that the infinitesimal metric is the square root of a quadratic form. Thanks to Finsler geometry, I clarify both the implicit and explicit hypotheses used for this justification. I explain that Riemann-Finsler's kind of method is also appropriate to deal with indefinite metrics. Nevertheless, Weyl shares with Helmholtz a strong commitment to the idea that the notion of group should be at the center of the foundations of geometry. Riemann missed this point, and that is why, according to Weyl, he dealt with the problem of space in a "too formal" way. As a consequence, to solve the problem of space, Weyl abandoned Riemann-Finsler's methods for group-theoretical ones. However, from a philosophical point of view, I show that Weyl and Helmholtz are in strong opposition. The meditation on Riemann's inaugural lecture, and its clear methodological separation between the infinitesimal and the finite parts of the problem of space, must have been crucial for Weyl, while searching for strong epistemological foundations for the group-theoretical methods, avoiding Helmholtz's unjustified transition from the finite to the infinitesimal.

  5. Neoclassical resonant transport of a mirror cell

    International Nuclear Information System (INIS)

    Ito, T.; Katanuma, I.

    2005-01-01

    The neoclassical resonant plateau transport in a mirror cell is studied theoretically. The analytical expression for a non-square-well magnetic field is obtained. The analytical result is applied to the GAMMA10 tandem mirror [T. Cho, M. Yoshida, J. Kohagura et al., Phys. Rev. Lett. 94, 085002-1 (2005)], which consists of several mirror cells in it, and the confinement time due to the neoclassical resonant plateau transport is determined in each mirror cell. It is found that the neoclassical resonant transport of ions trapped in the nonaxisymmetric anchor mirror cell and transition mirror cells is significantly smaller than those trapped in the central cell

  6. The Helmholtz Hierarchy: phase space statistics of cold dark matter

    International Nuclear Information System (INIS)

    Tassev, Svetlin V.

    2011-01-01

    We present a new formalism to study large-scale structure in the universe. The result is a hierarchy (which we call the ''Helmholtz Hierarchy'') of equations describing the phase space statistics of cold dark matter (CDM). The hierarchy features a physical ordering parameter which interpolates between the Zel'dovich approximation and fully-fledged gravitational interactions. The results incorporate the effects of stream crossing. We show that the Helmholtz hierarchy is self-consistent and obeys causality to all orders. We present an interpretation of the hierarchy in terms of effective particle trajectories

  7. Resonance computations for cells with fuel annuli

    International Nuclear Information System (INIS)

    Hwang, R.N.; Gelbard, E.M.

    1990-01-01

    Two methods have been developed for the computation of resonance integrals in cells containing annular fuel regions. Both are based on rational approximations. One is a generalization of a one-term rational approximation method developed by Segev for a cell with a single fuel annulus. The second modifies the earlier Chen-Gelbard two-term method originally used for double-heterogeneity calculations. Both methods were tested, in cells with two fuel annuli, for various U 235 and U 238 resonances. Both gives resonance integrals accurate enough for practical purposes. The two-term fits are substantially more accurate in some NR cases, but are somewhat more difficult to correct for finite resonance widths. 8 refs., 4 tabs

  8. Reconstruction of extended sources for the Helmholtz equation

    KAUST Repository

    Kress, Rainer; Rundell, William

    2013-01-01

    The basis of most imaging methods is to detect hidden obstacles or inclusions within a body when one can only make measurements on an exterior surface. Our underlying model is that of inverse acoustic scattering based on the Helmholtz equation. Our

  9. Improvement in transmission loss of aircraft double wall with resonators

    Science.gov (United States)

    Sun, Jincai; Shi, Liming; Ye, Xining

    1991-08-01

    A little volume low frequency resonator applicable to double-wall configuration of propeller-driven aircraft was designed on the basis of the principle of Helmholtz resonator. The normal incidence absorption coefficient of the various single resonator has been measured. The agreement between theoretical and experimental results is encouraging. An array of resonators whose resonant frequency at 85 Hz and 160 Hz, respectively, are installed between aircraft double-panel, and it has been shown that transmission loss of the double wall structure with resonators improve 4 dB and 6.5 dB in 1/3rd octave bandwidth at 80 Hz and 160 Hz center frequency, respectively, and 5 dB and 7 dB at resonant frequencies, compared with that of the double wall configuration without resonators.

  10. Rayleigh-Taylor and Kelvin-Helmholtz instabilities in targets accelerated by laser ablation

    International Nuclear Information System (INIS)

    Emery, M.H.; Gardner, J.H.; Boris, J.P.

    1982-01-01

    With use of the fast2d laser-shell model, the acceleration of a 20-μm-thick plastic foil up to 160 km/s has been simulated. It is possible to follow the Rayleigh-Taylor bubble-and-spike development far into the nonlinear regime and beyond the point of foil fragmentation. Strong shear flow develops which evolves into the Kelvin-Helmholtz instability. The Kelvin-Helmholtz instability causes the tips of the spikes to widen and as a result reduce their rate of ''fall.''

  11. Fourier-Based Fast Multipole Method for the Helmholtz Equation

    KAUST Repository

    Cecka, Cris

    2013-01-01

    The fast multipole method (FMM) has had great success in reducing the computational complexity of solving the boundary integral form of the Helmholtz equation. We present a formulation of the Helmholtz FMM that uses Fourier basis functions rather than spherical harmonics. By modifying the transfer function in the precomputation stage of the FMM, time-critical stages of the algorithm are accelerated by causing the interpolation operators to become straightforward applications of fast Fourier transforms, retaining the diagonality of the transfer function, and providing a simplified error analysis. Using Fourier analysis, constructive algorithms are derived to a priori determine an integration quadrature for a given error tolerance. Sharp error bounds are derived and verified numerically. Various optimizations are considered to reduce the number of quadrature points and reduce the cost of computing the transfer function. © 2013 Society for Industrial and Applied Mathematics.

  12. Determination of space-energy distribution of resonance neutrons in reactor lattice cell and calculation of resonance integrals

    International Nuclear Information System (INIS)

    Zmijarevic, I.

    1980-01-01

    Space-energy distribution of resonance neutrons in reactor lattice cell was determined by solving the Boltzmann equation by spherical harmonics method applying P-3 approximation. Computer code SPLET used for these calculations is described. Resonance absorption and calculation of resonance integrals are described as well. Effective resonance integral values for U-238 resonance at 6.7 Ev are calculated for heavy water reactor cell with metal, oxide and carbide fuel elements

  13. Optimization of field homogeneity of Helmholtz-like coils for measuring the balance of planar gradiometers

    International Nuclear Information System (INIS)

    Nordahn, M.A.; Holst, T.; Shen, Y.Q.

    1999-01-01

    Measuring the balance of planar SQUID gradiometers using a relatively small Helmholtz-like coil system requires a careful design of the coils in order to have a high degree of field uniformity along the radial direction. The level to which planar gradiometers can be balanced will be affected by any misalignment of the gradiometer relative to the ideal central position. Therefore, the maximum degree of balancing possible is calculated numerically for the Helmholtz geometry under various perturbations, including misalignment of the gradiometer along the cylindrical and the radial axis, and angular tilting relative to the normal plane. Furthermore, if the ratio between the coil separation and coil radius is chosen to be less than unity, calculations show that the expected radial uniformity of the field can be improved considerably compared to the traditional Helmholtz geometry. The optimized coil geometry is compared to the Helmholtz geometry and is found to yield up to an order of magnitude improvement of the worst case error signal within a volume spanned by the uncertainty in the alignment. (author)

  14. Square Helmholtz coil with homogeneous field for magnetic measurement of longer HTS tapes

    Energy Technology Data Exchange (ETDEWEB)

    Alamgir, A.K.M. [Applied Superconductivity Research Center, Department of Physics, Building Li Zhai, Room 209, Tsinghua University, Beijing 100084 (China)]. E-mail: alam643@hotmail.com; Fang, J. [Applied Superconductivity Research Center, Department of Physics, Building Li Zhai, Room 209, Tsinghua University, Beijing 100084 (China); Gu, C. [Applied Superconductivity Research Center, Department of Physics, Building Li Zhai, Room 209, Tsinghua University, Beijing 100084 (China); Han, Z. [Applied Superconductivity Research Center, Department of Physics, Building Li Zhai, Room 209, Tsinghua University, Beijing 100084 (China)

    2005-08-01

    Magnetic ac loss measurement of HTS tapes and films at various magnetic field orientations becomes a crucial issue from the view point of measurement precision. In principle, due to tiny loss component and anisotropic properties, longer HTS sample subjected to very good homogeneous field could facilitate the accuracy of this kind of measurement. We investigated field profile of Helmholtz coils with square winding as a magnetizer for HTS tape and films. It is found that square winding exhibits better field-homogeneity than that of conventional circular winding with the similar coil dimensions for ideal condition. Being apart from ideal condition, we investigated field profile of square Helmholtz coil with various combinations of coil parameters and made a conclusion for the best combination based on the field homogeneity and field intensity. The design also provides noise reduction facilities by allowing compact and identical pick up-compensation coil arrangement. In addition, we optimized the final design of Helmholtz coil to compensate the influence of difficulties in square winding on the field distribution. Finally, as small as 0.5% field variation was estimated for 50 mm long sample to be magnetized under a proper combination of fabrication parameters. Investigation of field homogeneity, noise effect and a practical design of square Helmholtz coil as a pick-up coil based magnetizer will be reported.

  15. Square Helmholtz coil with homogeneous field for magnetic measurement of longer HTS tapes

    International Nuclear Information System (INIS)

    Alamgir, A.K.M.; Fang, J.; Gu, C.; Han, Z.

    2005-01-01

    Magnetic ac loss measurement of HTS tapes and films at various magnetic field orientations becomes a crucial issue from the view point of measurement precision. In principle, due to tiny loss component and anisotropic properties, longer HTS sample subjected to very good homogeneous field could facilitate the accuracy of this kind of measurement. We investigated field profile of Helmholtz coils with square winding as a magnetizer for HTS tape and films. It is found that square winding exhibits better field-homogeneity than that of conventional circular winding with the similar coil dimensions for ideal condition. Being apart from ideal condition, we investigated field profile of square Helmholtz coil with various combinations of coil parameters and made a conclusion for the best combination based on the field homogeneity and field intensity. The design also provides noise reduction facilities by allowing compact and identical pick up-compensation coil arrangement. In addition, we optimized the final design of Helmholtz coil to compensate the influence of difficulties in square winding on the field distribution. Finally, as small as 0.5% field variation was estimated for 50 mm long sample to be magnetized under a proper combination of fabrication parameters. Investigation of field homogeneity, noise effect and a practical design of square Helmholtz coil as a pick-up coil based magnetizer will be reported

  16. Korteweg-de Vries description of Helmholtz-Kerr dark solitons

    Energy Technology Data Exchange (ETDEWEB)

    Christian, J M [Joule Physics Laboratory, School of Computing, Science and Engineering, Institute for Materials Research, University of Salford, Salford M5 4WT (United Kingdom) ; McDonald, G S [Joule Physics Laboratory, School of Computing, Science and Engineering, Institute for Materials Research, University of Salford, Salford M5 4WT (United Kingdom) ; Chamorro-Posada, P [Departmento de TeorIa de la Senal y Comunicaciones e IngenierIa Telematica, Universidad de Valladolid, ETSI Telecomunicacion, Campus Miguel Delibes s/n, 47011 Valladolid (Spain)

    2006-12-15

    A wide variety of different physical systems can be described by a relatively small set of universal equations. For example, small-amplitude nonlinear Schroedinger dark solitons can be described by a Korteweg-de Vries (KdV) equation. Reductive perturbation theory, based on linear boosts and Gallilean transformations, is often employed to establish connections to and between such universal equations. Here, a novel analytical approach reveals that the evolution of small-amplitude Helmholtz-Kerr dark solitons is also governed by a KdV equation. This broadens the class of nonlinear systems that are known to possess KdV soliton solutions, and provides a framework for perturbative analyses when propagation angles are not negligibly small. The derivation of this KdV equation involves an element that appears new to weakly nonlinear analyses, since transformations are required to preserve the rotational symmetry inherent to Helmholtz-type equations.

  17. Korteweg-de Vries description of Helmholtz-Kerr dark solitons

    International Nuclear Information System (INIS)

    Christian, J M; McDonald, G S; Chamorro-Posada, P

    2006-01-01

    A wide variety of different physical systems can be described by a relatively small set of universal equations. For example, small-amplitude nonlinear Schroedinger dark solitons can be described by a Korteweg-de Vries (KdV) equation. Reductive perturbation theory, based on linear boosts and Gallilean transformations, is often employed to establish connections to and between such universal equations. Here, a novel analytical approach reveals that the evolution of small-amplitude Helmholtz-Kerr dark solitons is also governed by a KdV equation. This broadens the class of nonlinear systems that are known to possess KdV soliton solutions, and provides a framework for perturbative analyses when propagation angles are not negligibly small. The derivation of this KdV equation involves an element that appears new to weakly nonlinear analyses, since transformations are required to preserve the rotational symmetry inherent to Helmholtz-type equations

  18. Kelvin-Helmholtz Instability: Lessons Learned and Ways Forward

    Science.gov (United States)

    Masson, A.; Nykyri, K.

    2018-06-01

    The Kelvin-Helmholtz instability (KHI) is a ubiquitous phenomenon across the Universe, observed from 500 m deep in the oceans on Earth to the Orion molecular cloud. Over the past two decades, several space missions have enabled a leap forward in our understanding of this phenomenon at the Earth's magnetopause. Key results obtained by these missions are first presented, with a special emphasis on Cluster and THEMIS. In particular, as an ideal instability, the KHI was not expected to produce mass transport. Simulations, later confirmed by spacecraft observations, indicate that plasma transport in Kelvin-Helmholtz (KH) vortices can arise during non-linear stage of its development via secondary process. In addition to plasma transport, spacecraft observations have revealed that KHI can also lead to significant ion heating due to enhanced ion-scale wave activity driven by the KHI. Finally, we describe what are the upcoming observational opportunities in 2018-2020, thanks to a unique constellation of multi-spacecraft missions including: MMS, Cluster, THEMIS, Van Allen Probes and Swarm.

  19. Capillary and viscous perturbations to Helmholtz flows

    KAUST Repository

    Moore, M. R.; Ockendon, H.; Ockendon, J. R.; Oliver, J. M.

    2014-01-01

    Inspired by recent calculations by Thoraval et al. (Phys. Rev. Lett., vol. 108, 2012, p. 264506) relating to droplet impact, this paper presents an analysis of the perturbations to the free surface caused by small surface tension and viscosity in steady Helmholtz flows. In particular, we identify the regimes in which appreciable vorticity can be shed from the boundary layer to the bulk flow. © 2014 Cambridge University Press.

  20. Capillary and viscous perturbations to Helmholtz flows

    KAUST Repository

    Moore, M. R.

    2014-02-21

    Inspired by recent calculations by Thoraval et al. (Phys. Rev. Lett., vol. 108, 2012, p. 264506) relating to droplet impact, this paper presents an analysis of the perturbations to the free surface caused by small surface tension and viscosity in steady Helmholtz flows. In particular, we identify the regimes in which appreciable vorticity can be shed from the boundary layer to the bulk flow. © 2014 Cambridge University Press.

  1. Exploring the resonant vibration of thin plates: Reconstruction of Chladni patterns and determination of resonant wave numbers.

    Science.gov (United States)

    Tuan, P H; Wen, C P; Chiang, P Y; Yu, Y T; Liang, H C; Huang, K F; Chen, Y F

    2015-04-01

    The Chladni nodal line patterns and resonant frequencies for a thin plate excited by an electronically controlled mechanical oscillator are experimentally measured. Experimental results reveal that the resonant frequencies can be fairly obtained by means of probing the variation of the effective impedance of the exciter with and without the thin plate. The influence of the extra mass from the central exciter is confirmed to be insignificant in measuring the resonant frequencies of the present system. In the theoretical aspect, the inhomogeneous Helmholtz equation is exploited to derive the response function as a function of the driving wave number for reconstructing experimental Chladni patterns. The resonant wave numbers are theoretically identified with the maximum coupling efficiency as well as the maximum entropy principle. Substituting the theoretical resonant wave numbers into the derived response function, all experimental Chladni patterns can be excellently reconstructed. More importantly, the dispersion relationship for the flexural wave of the vibrating plate can be determined with the experimental resonant frequencies and the theoretical resonant wave numbers. The determined dispersion relationship is confirmed to agree very well with the formula of the Kirchhoff-Love plate theory.

  2. Magnetized Kelvin-Helmholtz instability: theory and simulations in the Earth's magnetosphere context

    Science.gov (United States)

    Faganello, Matteo; Califano, Francesco

    2017-12-01

    The Kelvin-Helmholtz instability, proposed a long time ago for its role in and impact on the transport properties at magnetospheric flanks, has been widely investigated in the Earth's magnetosphere context. This review covers more than fifty years of theoretical and numerical efforts in investigating the evolution of Kelvin-Helmholtz vortices and how the rich nonlinear dynamics they drive allow solar wind plasma bubbles to enter into the magnetosphere. Special care is devoted to pointing out the main advantages and weak points of the different plasma models that can be adopted for describing the collisionless magnetospheric medium and in underlying the important role of the three-dimensional geometry of the system.

  3. Resonant cell of a double nuclear electron resonance spectrometer for performance in a 120-350 Gs magnetic field

    International Nuclear Information System (INIS)

    Baldin, V.I.; Stepanov, A.P.

    1976-01-01

    Spectrometer double-frequency resonance cell construction of a double nuclear electron resonance for operation in 120-350 Gs magnetic fields is described. The cell has been developed from a special decimeter resonator with a concentrated capacitance. The electric and magnetic components of a high frequency field are efficiently divided in the separator. Therefore, the insertion of a measuring coil and a sample in the maximum of the magnetic component of the field does not practically affect the distribution and parameters of the high-frequency field. The double-frequency resonance cell proposed provides for a higher accuracy of measuring amplifications of the nuclear magnetic resonance signals when there is the overhauzer effect for 120-350 Gs magnetic fields

  4. Sound-proof Sandwich Panel Design via Metamaterial Concept

    Science.gov (United States)

    Sui, Ni

    Sandwich panels consisting of hollow core cells and two face-sheets bonded on both sides have been widely used as lightweight and strong structures in practical engineering applications, but with poor acoustic performance especially at low frequency regime. Basic sound-proof methods for the sandwich panel design are spontaneously categorized as sound insulation and sound absorption. Motivated by metamaterial concept, this dissertation presents two sandwich panel designs without sacrificing weight or size penalty: A lightweight yet sound-proof honeycomb acoustic metamateiral can be used as core material for honeycomb sandwich panels to block sound and break the mass law to realize minimum sound transmission; the other sandwich panel design is based on coupled Helmholtz resonators and can achieve perfect sound absorption without sound reflection. Based on the honeycomb sandwich panel, the mechanical properties of the honeycomb core structure were studied first. By incorporating a thin membrane on top of each honeycomb core, the traditional honeycomb core turns into honeycomb acoustic metamaterial. The basic theory for such kind of membrane-type acoustic metamaterial is demonstrated by a lumped model with infinite periodic oscillator system, and the negative dynamic effective mass density for clamped membrane is analyzed under the membrane resonance condition. Evanescent wave mode caused by negative dynamic effective mass density and impedance methods are utilized to interpret the physical phenomenon of honeycomb acoustic metamaterials at resonance. The honeycomb metamaterials can extraordinarily improve low-frequency sound transmission loss below the first resonant frequency of the membrane. The property of the membrane, the tension of the membrane and the numbers of attached membranes can impact the sound transmission loss, which are observed by numerical simulations and validated by experiments. The sandwich panel which incorporates the honeycomb metamateiral as

  5. Coupled Kelvin-Helmholtz and Tearing Mode Instabilities at the Mercury's Magnetopause

    Science.gov (United States)

    Ivanovski, S. L.; Milillo, A.; Kartalev, M.; Massetti, S.

    2018-05-01

    A MHD approach for numerical simulations of coupled Kelvin-Helmholtz and tearing mode instabilities has been applied to Mercury’s magnetopause and used to perform a physical parameters study constrained by the MESSENGER data.

  6. The outlooks of Helmholtz, Plank and Einstein on the unified physical theory

    International Nuclear Information System (INIS)

    Treder, G.Yu.

    1982-01-01

    The outlooks of Helmholtz, Planck and Einstein on the unified physical theory are exposed. Planck formulated the Einstein relativistic mechanics in the canonical form stemming from the suggested by Helmholtz approach that the principle of action is the unified formal principle of physics. Einstein and his companious proceeded from machroscopic fields in the attempts to prove the unified geometric field theory. The sense of Planck length as ''the smallest length in physics'' is determined, on the one hand, by the Heizenberg uncerntainty principle for the measurement process, and on the other hand by the universal proportionality between inertia and gravity. It results from geometrical nature and gravitational potential, i. e. from Einstein interpretation of the equivalence principle

  7. A numerical study on acoustic behavior in gas turbine combustor with acoustic resonator

    International Nuclear Information System (INIS)

    Park, I Sun; Sohn, Chae Hoon

    2005-01-01

    Acoustic behavior in gas turbine combustor with acoustic resonator is investigated numerically by adopting linear acoustic analysis. Helmholtz-type resonator is employed as acoustic resonator to suppress acoustic instability passively. The tuning frequency of acoustic resonator is adjusted by varying its length. Through harmonic analysis, acoustic-pressure responses of chamber to acoustic excitation are obtained and the resonant acoustic modes are identified. Acoustic damping effect of acoustic resonator is quantified by damping factor. As the tuning frequency of acoustic resonator approaches the target frequency of the resonant mode to be suppressed, mode split from the original resonant mode to lower and upper modes appears and thereby complex patterns of acoustic responses show up. Considering mode split and damping effect as a function of tuning frequency, it is desirable to make acoustic resonator tuned to broad-band frequencies near the maximum frequency of those of the possible upper modes

  8. The use of acoustically tuned resonators to improve the sound transmission loss of double panel partitions

    Science.gov (United States)

    Mason, J. M.; Fahy, F. J.

    1986-10-01

    The effectiveness of tuned Helmholtz resonators connected to the partition cavity in double-leaf partitions utilized in situations requiring low weight structures with high transmission loss is investigated as a method of improving sound transmission loss. This is demonstrated by a simple theoretical model and then experimentally verified. Results show that substantial improvements may be obtained at and around the mass-air-mass frequency for a total resonator volume 15 percent of the cavity volume.

  9. Can Hall effect trigger Kelvin-Helmholtz instability in sub-Alfvénic flows?

    Science.gov (United States)

    Pandey, B. P.

    2018-05-01

    In the Hall magnetohydrodynamics, the onset condition of the Kelvin-Helmholtz instability is solely determined by the Hall effect and is independent of the nature of shear flows. In addition, the physical mechanism behind the super- and sub-Alfvénic flows becoming unstable is quite different: the high-frequency right circularly polarized whistler becomes unstable in the super-Alfvénic flows whereas low-frequency, left circularly polarized ion-cyclotron wave becomes unstable in the presence of sub-Alfvénic shear flows. The growth rate of the Kelvin-Helmholtz instability in the super-Alfvénic case is higher than the corresponding ideal magnetohydrodynamic rate. In the sub-Alfvénic case, the Hall effect opens up a new, hitherto inaccessible (to the magnetohydrodynamics) channel through which the partially or fully ionized fluid can become Kelvin-Helmholtz unstable. The instability growth rate in this case is smaller than the super-Alfvénic case owing to the smaller free shear energy content of the flow. When the Hall term is somewhat smaller than the advection term in the induction equation, the Hall effect is also responsible for the appearance of a new overstable mode whose growth rate is smaller than the purely growing Kelvin-Helmholtz mode. On the other hand, when the Hall diffusion dominates the advection term, the growth rate of the instability depends only on the Alfvén -Mach number and is independent of the Hall diffusion coefficient. Further, the growth rate in this case linearly increases with the Alfvén frequency with smaller slope for sub-Alfvénic flows.

  10. Two numerical methods for an inverse problem for the 2-D Helmholtz equation

    CERN Document Server

    Gryazin, Y A; Lucas, T R

    2003-01-01

    Two solution methods for the inverse problem for the 2-D Helmholtz equation are developed, tested, and compared. The proposed approaches are based on a marching finite-difference scheme which requires the solution of an overdetermined system at each step. The preconditioned conjugate gradient method is used for rapid solutions of these systems and an efficient preconditioner has been developed for this class of problems. Underlying target applications include the imaging of land mines, unexploded ordinance, and pollutant plumes in environmental cleanup sites, each formulated as an inverse problem for a 2-D Helmholtz equation. The images represent the electromagnetic properties of the respective underground regions. Extensive numerical results are presented.

  11. Magnetic resonance investigation of magnetic-labeled baker's yeast cells

    International Nuclear Information System (INIS)

    Godoy Morais, J.P.M.; Azevedo, R.B.; Silva, L.P.; Lacava, Z.G.M.; Bao, S.N.; Silva, O.; Pelegrini, F.; Gansau, C.; Buske, N.; Safarik, I.; Safarikova, M.; Morais, P.C.

    2004-01-01

    In this study, the interaction of DMSA-coated magnetite nanoparticles (5 and 10 nm core-size) with Saccharomyces cerevisae was investigated using magnetic resonance (MR) and transmission electron microscopy (TEM). The TEM micrographs revealed magnetite nanoparticles attached externally to the cell wall. The MR data support the strong interaction among the nanoparticles supported by the cells. A remarkable shift in the resonance field was used as signature of particle attachment to the cell wall

  12. Preserving the Helmholtz dispersion relation: One-way acoustic wave propagation using matrix square roots

    Science.gov (United States)

    Keefe, Laurence

    2016-11-01

    Parabolized acoustic propagation in transversely inhomogeneous media is described by the operator update equation U (x , y , z + Δz) =eik0 (- 1 +√{ 1 + Z }) U (x , y , z) for evolution of the envelope of a wavetrain solution to the original Helmholtz equation. Here the operator, Z =∇T2 + (n2 - 1) , involves the transverse Laplacian and the refractive index distribution. Standard expansion techniques (on the assumption Z << 1)) produce pdes that approximate, to greater or lesser extent, the full dispersion relation of the original Helmholtz equation, except that none of them describe evanescent/damped waves without special modifications to the expansion coefficients. Alternatively, a discretization of both the envelope and the operator converts the operator update equation into a matrix multiply, and existing theorems on matrix functions demonstrate that the complete (discrete) Helmholtz dispersion relation, including evanescent/damped waves, is preserved by this discretization. Propagation-constant/damping-rates contour comparisons for the operator equation and various approximations demonstrate this point, and how poorly the lowest-order, textbook, parabolized equation describes propagation in lined ducts.

  13. Continuous versus discrete structures II -- Discrete Hamiltonian systems and Helmholtz conditions

    OpenAIRE

    Cresson, Jacky; Pierret, Frédéric

    2015-01-01

    We define discrete Hamiltonian systems in the framework of discrete embeddings. An explicit comparison with previous attempts is given. We then solve the discrete Helmholtz's inverse problem for the discrete calculus of variation in the Hamiltonian setting. Several applications are discussed.

  14. HNF - Helmholtz Nano Facility

    Directory of Open Access Journals (Sweden)

    Wolfgang Albrecht

    2017-05-01

    Full Text Available The Helmholtz Nano Facility (HNF is a state-of-the-art cleanroom facility. The cleanroom has ~1100 m2 with cleanroom classes of DIN ISO 1-3. HNF operates according to VDI DIN 2083, Good Manufacturing Practice (GMP and aquivalent to Semiconductor Industry Association (SIA standards. HNF is a user facility of Forschungszentrum Jülich and comprises a network of facilities, processes and systems for research, production and characterization of micro- and nanostructures. HNF meets the basic supply of micro- and nanostructures for nanoelectronics, fluidics. micromechanics, biology, neutron and energy science, etc.. The task of HNF is rapid progress in nanostructures and their technology, offering efficient access to infrastructure and equipment. HNF gives access to expertise and provides resources in production, synthesis, characterization and integration of structures, devices and circuits. HNF covers the range from basic research to application oriented research facilitating a broad variety of different materials and different sample sizes.

  15. Scattering anomalies in a resonator above the thresholds of the continuous spectrum

    Energy Technology Data Exchange (ETDEWEB)

    Nazarov, S A [St. Petersburg State Politechnical University, St. Petersburg (Russian Federation)

    2015-06-30

    We consider the Dirichlet spectral problem for the Laplace operator in a multi-dimensional domain with a cylindrical outlet to infinity, a Helmholtz resonator. Using asymptotic analysis of the scattering matrix we demonstrate different types of reflection of high-amplitude near-threshold waves. One scattering type or another, unstable or stable with respect to variations of the resonator shapes, is determined by the presence or absence of stabilizing solutions at the threshold frequency, respectively. In a waveguide with two cylindrical outlets to infinity, we discover the effect of almost complete passage of the wave under 'fine tuning' of the resonator. Bibliography: 26 titles.

  16. A third note: Helmholtz, Palestrina, and the Early History of Musicology

    NARCIS (Netherlands)

    Kursell, J.

    2015-01-01

    This contribution focuses on Hermann von Helmholtz’s work on Renaissance composer Giovanni Pierluigi da Palestrina. Helmholtz used his scientific concept of distortion to analyze this music and, reversely, to find corroboration for the concept in his musical analyses. In this, his work interlocked

  17. Calibration of Helmholtz Coils for the characterization of MEMS magnetic sensor using fluxgate magnetometer with DAS1 magnetic range data acquisition system

    Science.gov (United States)

    Ahmad, Farooq; Dennis, John Ojur; Md Khir, Mohd Haris; Hamid, Nor Hisham

    2012-09-01

    This paper presents the calibration of Helmholtz coils for the characterization of MEMS Magnetic sensor using Fluxgate magnetometer with DAS1 Magnetic Range Data Acquisition System. The Helmholtz coils arrangement is often used to generate a uniform magnetic field in space. In the past, standard magnets were used to calibrate the Helmholtz coils. A method is presented here for calibrating these coils using a Fluxgate magnetometer and known current source, which is easier and results in greater accuracy.

  18. Implicit Boundary Integral Methods for the Helmholtz Equation in Exterior Domains

    Science.gov (United States)

    2016-06-01

    solve the Helmholtz equation as ∂Ω goes through significant change in its shape and topology — applications for which implicit representation of the...boundary-value problems for the wave equation and maxwell’s equations. Russian Math . Surv., 1965. [16] S. Reutskiy. The method of fundamental

  19. Kelvin-Helmholtz instability in a weakly ionized layer

    OpenAIRE

    Shadmehri, Mohsen; Downes, Turlough P.

    2007-01-01

    We study the linear theory of Kelvin-Helmholtz instability in a layer of ions and neutrals with finite thickness. In the short wavelength limit the thickness of the layer has a negligible effect on the growing modes. However, perturbations with wavelength comparable to layer's thickness are significantly affected by the thickness of the layer. We show that the thickness of the layer has a stabilizing effect on the two dominant growing modes. Transition between the modes not only depends on th...

  20. Semi-analytic solution to planar Helmholtz equation

    Directory of Open Access Journals (Sweden)

    Tukač M.

    2013-06-01

    Full Text Available Acoustic solution of interior domains is of great interest. Solving acoustic pressure fields faster with lower computational requirements is demanded. A novel solution technique based on the analytic solution to the Helmholtz equation in rectangular domain is presented. This semi-analytic solution is compared with the finite element method, which is taken as the reference. Results show that presented method is as precise as the finite element method. As the semi-analytic method doesn’t require spatial discretization, it can be used for small and very large acoustic problems with the same computational costs.

  1. Sensitivity Filters In Topology Optimisation As A Solution To Helmholtz Type Differential Equation

    DEFF Research Database (Denmark)

    Lazarov, Boyan Stefanov; Sigmund, Ole

    2009-01-01

    The focus of the study in this article is on the use of a Helmholtz type differential equation as a filter for topology optimisation problems. Until now various filtering schemes have been utilised in order to impose mesh independence in this type of problems. The usual techniques require topology...... information about the neighbour sub-domains is an expensive operation. The proposed filtering technique requires only mesh information necessary for the finite element discretisation of the problem. The main idea is to define the filtered variable implicitly as a solution of a Helmholtz type differential...... equation with homogeneous Neumann boundary conditions. The properties of the filter are demonstrated for various 2D and 3D topology optimisation problems in linear elasticity, solved on sequential and parallel computers....

  2. [Scientific theoretical founding of medicine as a natural science by Hermann von Helmholtz (1821-1894)].

    Science.gov (United States)

    Neumann, J N

    1994-01-01

    In this study an attempt will be made to discuss the epistemological problems in the theory and practice of modern technical medicine in the writings of Hermann von Helmholz. An inquiry into the relationship between von Helmholtz' thinking and the critical philosophy of Immanuel Kant is followed by the characteristics of von Helmholtz' philosophy of science which he himself called "empirical theory". The question of medicine as a science finally leads to the main problem of medical epistemology, viz., the relationship between theoretical knowledge and practice in medicine. In this context the anthropological dimension is brought into consideration.

  3. Extreme Wave-Induced Oscillation in Paradip Port Under the Resonance Conditions

    Science.gov (United States)

    Kumar, Prashant; Gulshan

    2017-12-01

    A mathematical model is constructed to analyze the long wave-induced oscillation in Paradip Port, Odisha, India under the resonance conditions to avert any extreme wave hazards. Boundary element method (BEM) with corner contribution is utilized to solve the Helmholtz equation under the partial reflection boundary conditions. Furthermore, convergence analysis is also performed for the boundary element scheme with uniform and non-uniform discretization of the boundary. The numerical scheme is also validated with analytic approximation and existing studies based on harbor resonance. Then, the amplification factor is estimated at six key record stations in the Paradip Port with multidirectional incident waves and resonance modes are also estimated at the boundary of the port. Ocean surface wave field is predicted in the interior of Paradip Port for the different directional incident wave at various resonance modes. Moreover, the safe locations in the port have been identified for loading and unloading of moored ship with different resonance modes and directional incident waves.

  4. Simulation of a resonant-type ring magnet power supply with multiple resonant cells and energy storage chokes

    International Nuclear Information System (INIS)

    Kim, J.M.S.; Blackmore, E.W.; Reiniger, K.W.

    1992-01-01

    For the TRIUMF KAON Factory Booster Ring, a resonant-type magnet power supply has been proposed for the dipole magnet excitation. The Booster Ring magnet power supply system based on resonant circuits, coupled with distributed energy make-up networks, is a complex system, sensitive to many system parameters. When multiple resonant cells, each with its own energy make-up network, are connected in a ring, it is very difficult to derive closed-form solutions to determine the operating conditions of the power supply system. A meaningful way to understand and analyze such a complex system is to use a simulation tool. This paper presents the analysis of operating conditions of the resonant-type ring magnet power supply with multiple resonant cells, using the circuit simulation tool, SPICE. The focus of the study is on the effect of circuit parameter variations in energy storage chokes

  5. Collisionless Kelvin-Helmholtz instability and vortex-induced reconnection in the external region of the Earth magnetotail

    International Nuclear Information System (INIS)

    Pegoraro, F; Faganello, M; Califano, F

    2008-01-01

    In a magnetized plasma streaming with a non uniform velocity, the Kelvin-Helmholtz instability plays a major role in mixing different plasma regions and in stretching the magnetic field lines leading to the formation of layers with a sheared magnetic field where magnetic field line reconnection can take place. A relevant example is provided by the formation of a mixing layer between the Earth's magnetosphere and the solar wind at low latitudes during northward periods. In the considered configuration, in the presence of a magnetic field nearly perpendicular to the plane defined by the velocity field and its inhomogeneity direction, velocity shear drives a Kelvin-Helmholtz instability which advects and distorts the magnetic field configuration. If the Alfven velocity associated to the in-plane magnetic field is sufficiently weak with respect to the variation of the fluid velocity in the plasma, the Kelvin-Helmholtz instability generates fully rolled-up vortices which advect the magnetic field lines into a complex configuration, causing the formation of current layers along the inversion curves of the in-plane magnetic field component. Pairing of the vortices generated by the Kelvin-Helmholtz instability is a well know phenomenon in two-dimensional hydrodynamics. Here we investigate the development of magnetic reconnection during the vortex pairing process and show that completely different magnetic structures are produced depending on how fast the reconnection process develops on the time scale set by the pairing process.

  6. Helmholtz and Diffusion Equations Associated with Local Fractional Derivative Operators Involving the Cantorian and Cantor-Type Cylindrical Coordinates

    Directory of Open Access Journals (Sweden)

    Ya-Juan Hao

    2013-01-01

    Full Text Available The main object of this paper is to investigate the Helmholtz and diffusion equations on the Cantor sets involving local fractional derivative operators. The Cantor-type cylindrical-coordinate method is applied to handle the corresponding local fractional differential equations. Two illustrative examples for the Helmholtz and diffusion equations on the Cantor sets are shown by making use of the Cantorian and Cantor-type cylindrical coordinates.

  7. Nuclear safety research in HGF 2012; Fortschrittsbericht 2012. Programm 'Nukleare Sicherheitsforschung' Helmholtz-Gemeinschaft

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2013-06-15

    After the events at the Japanese nuclear power plant of Fukushima Daiichi, the German Federal government decided that Germany will give up electricity generation from nuclear power within a decade. The last reactor will be disconnected from the power grid in 2022. Helping to make this opt-out safe is one of the duties of the Helmholtz Association with its Nuclear Safety Research Program within the Energy Research Area. Also the demolition of nuclear power plants and the repository problem will keep society, and thus also research, busy for a number of decades to come. Giving up electricity production from nuclear power thus must not mean giving up the required nuclear technology competences. In the fields of reactor safety, demolition, final storage, radiation protection, and crisis management, in critical support of international developments, and for competent evaluation of nuclear facilities around Germany, these competences will be in demand far beyond the German opt-out. This is the reason why the final report by the Ethics Committee on 'Safe Energy Supply' emphasizes the importance of nuclear technology research. Close cooperation on national, European and international levels is indispensable in this effort. Also nuclear safety research in the Helmholtz Association is aligned with the challenges posed by the opt-out of the use of nuclear power. It is important that the high competences in the areas of plant safety and demolition, handling of radioactive waste, and safe final storage as well as radiation protection be preserved. The Nuclear Safety Research Program within the Energy Research Area of the Helmholtz Association therefore will continue studying scientific and technical aspects of the safety of nuclear reactors and the safety of nuclear waste management. These research activities are provident research conducted for society and must be preserved for a long period of time. The work is closely harmonized with the activities of the partners

  8. Oscillation thresholds for "striking outwards" reeds coupled to a resonator

    OpenAIRE

    Silva , Fabrice; Kergomard , Jean; Vergez , Christophe

    2007-01-01

    International audience; This paper considers a "striking outwards" reed coupled to a resonator. This expression, due to Helmholtz, is not discussed here : it corresponds to the most common model of a lip-type valve, when the valve is assumed to be a one degree of freedom oscillator. The presented work is an extension of the works done by Wilson and Beavers (1974), Tarnopolsky (2000). The range of the playing frequencies is investigated. The first results are analytical : when no losses are pr...

  9. Cyclotron resonance in a cathode ray tube

    International Nuclear Information System (INIS)

    Gherbanovschi, N.; Tanasa, M.; Stoican, O.

    2002-01-01

    Absorption of the RF energy by the electron beam in a cathode ray tube due to the cyclotron resonance is described. The cathode ray tube is placed within a Helmholtz coils system supplied by a sawtooth current generator. In order to generate RF field and to detect RF absorption a gate dip-meter equipped with a FET transistor is used. The bias voltage variations of the FET transistors as a function of the magnetic field are recorded. The operating point of the cathode ray tube has been chosen so that the relaxation oscillations of the detection system can be observed. (authors)

  10. Effect of plasma density profile of tokamak on Kelvin-Helmholtz instability

    International Nuclear Information System (INIS)

    Tang Fulin

    1984-01-01

    The purpose of this paper is to study the effect of radial distribution of plasma density profile of tokamak on Kelvin-Helmholtz instability caused by toroidal rotation. The effect of radial distribution of plasma rotational velocity on stability is also examine for comparison. It is found that within the range of tokamak parameters the only radial distribution of plasma rotational velocity cannot induce Kelvin-Helmholtz instability. On the contrary, when there is a radial distribution of plasma density, i.e. P 01 =P 0 e -tx and V 0 1 = const, plasma becomes unstable, and instability will increase proportionally to the value of t. Meanwhile when the value of t remains constant, the instability growth rate will decrease if P 0 grows or the distance between plasma and wall of container decreases too. It shows that the Kelvin-Helmoltz instability is not only influenced by the steepness of density profile but also by the inertia of plasma in central region, which is helpful for depressing the instability. (author). 5 refs, 4 figs, 2 tabs

  11. The Common Data Acquisition Platform in the Helmholtz Association

    International Nuclear Information System (INIS)

    Kaever, P.; Balzer, M.; Kopmann, A.; Zimmer, M.; Rongen, H.

    2017-01-01

    Various centres of the German Helmholtz Association (HGF) started in 2012 to develop a modular data acquisition (DAQ) platform, covering the entire range from detector readout to data transfer into parallel computing environments. This platform integrates generic hardware components like the multi-purpose HGF-Advanced Mezzanine Card or a smart scientific camera framework, adding user value with Linux drivers and board support packages. Technically the scope comprises the DAQ-chain from FPGA-modules to computing servers, notably frontend-electronics-interfaces, microcontrollers and GPUs with their software plus high-performance data transmission links. The core idea is a generic and component-based approach, enabling the implementation of specific experiment requirements with low effort. This so called DTS-platform will support standards like MTCA.4 in hard- and software to ensure compatibility with commercial components. Its capability to deploy on other crate standards or FPGA-boards with PCI express or Ethernet interfaces remains an essential feature. Competences of the participating centres are coordinated in order to provide a solid technological basis for both research topics in the Helmholtz Programme ''Matter and Technology'': ''Detector Technology and Systems'' and ''Accelerator Research and Development''. The DTS-platform aims at reducing costs and development time and will ensure access to latest technologies for the collaboration. Due to its flexible approach, it has the potential to be applied in other scientific programs.

  12. The Common Data Acquisition Platform in the Helmholtz Association

    Science.gov (United States)

    Kaever, P.; Balzer, M.; Kopmann, A.; Zimmer, M.; Rongen, H.

    2017-04-01

    Various centres of the German Helmholtz Association (HGF) started in 2012 to develop a modular data acquisition (DAQ) platform, covering the entire range from detector readout to data transfer into parallel computing environments. This platform integrates generic hardware components like the multi-purpose HGF-Advanced Mezzanine Card or a smart scientific camera framework, adding user value with Linux drivers and board support packages. Technically the scope comprises the DAQ-chain from FPGA-modules to computing servers, notably frontend-electronics-interfaces, microcontrollers and GPUs with their software plus high-performance data transmission links. The core idea is a generic and component-based approach, enabling the implementation of specific experiment requirements with low effort. This so called DTS-platform will support standards like MTCA.4 in hard- and software to ensure compatibility with commercial components. Its capability to deploy on other crate standards or FPGA-boards with PCI express or Ethernet interfaces remains an essential feature. Competences of the participating centres are coordinated in order to provide a solid technological basis for both research topics in the Helmholtz Programme ``Matter and Technology'': ``Detector Technology and Systems'' and ``Accelerator Research and Development''. The DTS-platform aims at reducing costs and development time and will ensure access to latest technologies for the collaboration. Due to its flexible approach, it has the potential to be applied in other scientific programs.

  13. Combined Helmholtz Integral Equation - Fourier series formulation of acoustical radiation and scattering problems

    CSIR Research Space (South Africa)

    Fedotov, I

    2006-07-01

    Full Text Available The Combined Helmholtz Integral Equation – Fourier series Formulation (CHIEFF) is based on representation of a velocity potential in terms of Fourier series and finding the Fourier coefficients of this expansion. The solution could be substantially...

  14. Development of ultrasonic electrostatic microjets for distributed propulsion and microflight

    Science.gov (United States)

    Amirparviz, Babak

    This dissertation details the first attempt to design and fabricate a distributed micro propulsion system based on acoustic streaming. A novel micro propulsion method is suggested by combining Helmholtz resonance, acoustic streaming and flow entrainment and thrust augmentation. In this method, oscillatory motion of an electrostatically actuated diaphragm creates a high frequency acoustic field inside the cavity of a Helmholtz resonator. The initial fluid motion velocity is amplified by the Helmholtz resonator structure and creates a jet flow at the exit nozzle. Acoustic streaming is the phenomenon responsible for primary jet stream creation. Primary jets produced by a few resonators can be combined in an ejector configuration to induce flow entrainment and thrust augmentation. Basic governing equations for the electrostatic actuator, deformation of the diaphragm and the fluid flow inside the resonator are derived. These equations are linearized and used to derive an equivalent electrical circuit model for the operation of the device. Numerical solution of the governing equations and simulation of the circuit model are used to predict the performance of the experimental systems. Thrust values as high as 30.3muN are expected per resonator. A micro machined electrostatically-driven high frequency Helmholtz resonator prototype is designed and fabricated. A new micro fabrication technique is developed for bulk micromachining and in particular fabrication of the resonator. Geometric stops for wet anisotropic etching of silicon are introduced for the fist time for structure formation. Arrays of high frequency (>60kHz) micro Helmholtz resonators are fabricated. In one sample more than 1000 resonators cover the surface of a four-inch silicon wafer and in effect convert it to a distributed propulsion system. A high yield (>85%) micro fabrication process is presented for realization of this propulsion system taking advantage of newly developed deep glass micromachining and

  15. Calculation of the beam injector steering system using Helmholtz coils

    International Nuclear Information System (INIS)

    Passaro, A.; Sircilli Neto, F.; Migliano, A.C.C.

    1991-03-01

    In this work, a preliminary evaluation of the beam injector steering system of the IEAv electron linac is presented. From the existing injector configuration and with the assumptions of monoenergetic beam (100 keV) and uniform magnetic field, two pairs of Helmholtz coils were calculated for the steering system. Excitations of 105 A.turn and 37 A.turn were determined for the first and second coils, respectively. (author)

  16. Thermoviscous analysis of open photoacoustic cells

    Science.gov (United States)

    Mannoor, Madhusoodanan; Kang, Sangmo

    2017-11-01

    Open photoacoustic cells, apart from the conventional spectroscopic applications, are increasingly useful in bio medical applications such as in vivo blood sugar measurement. Maximising the acoustic pressure amplitude and the quality factor are major design considerations associated with open cells.Conventionaly, resonant photoacoustic cells are analyzed by either transmission line analogy or Eigen mode expansion method. In this study, we conducted a more comprehensive thermo viscous analysis of open photoacoustic cells. A Helmholtz cell and a T-shaped cell, which are acoustically different, are considered for analysis. Effect of geometrical dimensions on the acoustic pressure, quality factor and the intrusion of noise are analyzed and compared between these cells. Specific attention is given to the sizing of the opening and fixtures on it to minimize the radiational losses and the intrusion of noise. Our results are useful for proper selection of the type of open photoacoustic cells for in vivo blood sugar measurement and the optimization of geometric variables of such cells. This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT and future planning (2017R1A2B4005006).

  17. Black and gray Helmholtz-Kerr soliton refraction

    International Nuclear Information System (INIS)

    Sanchez-Curto, Julio; Chamorro-Posada, Pedro; McDonald, Graham S.

    2011-01-01

    Refraction of black and gray solitons at boundaries separating different defocusing Kerr media is analyzed within a Helmholtz framework. A universal nonlinear Snell's law is derived that describes gray soliton refraction, in addition to capturing the behavior of bright and black Kerr solitons at interfaces. Key regimes, defined by beam and interface characteristics, are identified, and predictions are verified by full numerical simulations. The existence of a unique total nonrefraction angle for gray solitons is reported; both internal and external refraction at a single interface is shown possible (dependent only on incidence angle). This, in turn, leads to the proposal of positive or negative lensing operations on soliton arrays at planar boundaries.

  18. CFD simulation of Kelvin-Helmholtz instability

    International Nuclear Information System (INIS)

    Strubelj, L.; Tiselj, I.

    2005-01-01

    Kelvin-Helmholtz instability appears in stratified two-fluid flow at surface. When the relative velocity is higher than the critical relative velocity, the growth of waves occurs. The experiment of Thorpe [1] used as a benchmark in the present paper, is made in a rectangular glass tube filled with two immiscible fluids of various densities. We simulated the growth of instability with CFX-5.7 code and compared simulation with analytical solution. It was found that surface tension force, which stabilizes growth of waves, actually has a destabilizing effect in simulation, unless very small timestep and residual is used. In CFX code system of nonlinear Navier-Stokes equations is linearised and solved iterative in each timestep, until prescribed residual is achieved. On the other hand, simulation without surface tension force is more stable than analytical result predicts. (author)

  19. Static harmonization of dynamically harmonized Fourier transform ion cyclotron resonance cell.

    Science.gov (United States)

    Zhdanova, Ekaterina; Kostyukevich, Yury; Nikolaev, Eugene

    2017-08-01

    Static harmonization in the Fourier transform ion cyclotron resonance cell improves the resolving power of the cell and prevents dephasing of the ion cloud in the case of any trajectory of the charged particle, not necessarily axisymmetric cyclotron (as opposed to dynamic harmonization). We reveal that the Fourier transform ion cyclotron resonance cell with dynamic harmonization (paracell) is proved to be statically harmonized. The volume of the statically harmonized potential distribution increases with an increase in the number of trap segments.

  20. High quality-factor fano metasurface comprising a single resonator unit cell

    Science.gov (United States)

    Sinclair, Michael B.; Warne, Larry K.; Basilio, Lorena I.; Langston, William L.; Campione, Salvatore; Brener, Igal; Liu, Sheng

    2017-06-20

    A new monolithic resonator metasurface design achieves ultra-high Q-factors while using only one resonator per unit cell. The metasurface relies on breaking the symmetry of otherwise highly symmetric resonators to induce intra-resonator mixing of bright and dark modes (rather than inter-resonator couplings), and is scalable from the near-infrared to radio frequencies and can be easily implemented in dielectric materials. The resulting high-quality-factor Fano metasurface can be used in many sensing, spectral filtering, and modulation applications.

  1. Magnetic resonance imaging and cell-based neurorestorative therapy after brain injury

    Directory of Open Access Journals (Sweden)

    Quan Jiang

    2016-01-01

    Full Text Available Restorative cell-based therapies for experimental brain injury, such as stroke and traumatic brain injury, substantially improve functional outcome. We discuss and review state of the art magnetic resonance imaging methodologies and their applications related to cell-based treatment after brain injury. We focus on the potential of magnetic resonance imaging technique and its associated challenges to obtain useful new information related to cell migration, distribution, and quantitation, as well as vascular and neuronal remodeling in response to cell-based therapy after brain injury. The noninvasive nature of imaging might more readily help with translation of cell-based therapy from the laboratory to the clinic.

  2. A Third Note: Helmholtz, Palestrina, and the Early History of Musicology.

    Science.gov (United States)

    Kursell, Julia

    2015-06-01

    This contribution focuses on Hermann von Helmholtz's work on Renaissance composer Giovanni Pierluigi da Palestrina. Helmholtz used his scientific concept of distortion to analyze this music and, reversely, to find corroboration for the concept in his musical analyses. In this, his work interlocked with nineteenth-century aesthetic and scholarly ideals. His eagerness to use the latest products of historical scholarship in early music reveals a specific view of music history. Historical documents of music provide the opportunity for the discovery of new experimental research topics and thereby also reveal insights into hearing under different conditions. The essay argues that this work occupies a peculiar position in the history of musicology; it falls under the header of "systematic musicology," which eventually emerged as a discipline of musicology at the end of the nineteenth century. That this discipline has a history at all is easily overlooked, as many of its contributors were scientists with an interest in music. A history of musicology therefore must consider at least the following two caveats: parts of it take place outside the institutionalized field of musicology, and any history of musicology must, in the last instance, be embedded in a history of music.

  3. Reconstruction of extended sources for the Helmholtz equation

    International Nuclear Information System (INIS)

    Kress, Rainer; Rundell, William

    2013-01-01

    The basis of most imaging methods is to detect hidden obstacles or inclusions within a body when one can only make measurements on an exterior surface. Our underlying model is that of inverse acoustic scattering based on the Helmholtz equation. Our inclusions are interior forces with compact support and our data consist of a single measurement of near-field Cauchy data on the external boundary. We propose an algorithm that under certain assumptions allows for the determination of the support set of these forces by solving a simpler ‘equivalent point source’ problem, and which uses a Newton scheme to improve the corresponding initial approximation. (paper)

  4. Reconstruction of extended sources for the Helmholtz equation

    KAUST Repository

    Kress, Rainer

    2013-02-26

    The basis of most imaging methods is to detect hidden obstacles or inclusions within a body when one can only make measurements on an exterior surface. Our underlying model is that of inverse acoustic scattering based on the Helmholtz equation. Our inclusions are interior forces with compact support and our data consist of a single measurement of near-field Cauchy data on the external boundary. We propose an algorithm that under certain assumptions allows for the determination of the support set of these forces by solving a simpler \\'equivalent point source\\' problem, and which uses a Newton scheme to improve the corresponding initial approximation. © 2013 IOP Publishing Ltd.

  5. HelmholtzZentrum Muenchen Deutsches Forschungszentrum fuer Gesundheit und Umwelt. Annual report 2011; HelmholtzZentrum Muenchen Deutsches Forschungszentrum fuer Gesundheit und Umwelt. Jahresbericht 2011

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-11-01

    The contribution under consideration is the annual report 2011 of the German Research Centre for Environmental Health (HelmholtzZentrum Munich, Federal Republic of Germany). The most important component of this annual report are the scientific highlights according to the following topics: (1) Systems researches for the health (M. Hrabe de Angelis); (2) Mechanisms of the interaction between genes and environment (M. Goetz); (3) Research of the metabolism (M. Tschoep); (4) Research of lungs and allergies (O. Eickelberg); (5) Technologies for the bio medicine (V. Ntziachristos); (6) Natural basis of existence (J. Durner).

  6. Outer hair cell piezoelectricity: frequency response enhancement and resonance behavior.

    Science.gov (United States)

    Weitzel, Erik K; Tasker, Ron; Brownell, William E

    2003-09-01

    Stretching or compressing an outer hair cell alters its membrane potential and, conversely, changing the electrical potential alters its length. This bi-directional energy conversion takes place in the cell's lateral wall and resembles the direct and converse piezoelectric effects both qualitatively and quantitatively. A piezoelectric model of the lateral wall has been developed that is based on the electrical and material parameters of the lateral wall. An equivalent circuit for the outer hair cell that includes piezoelectricity shows a greater admittance at high frequencies than one containing only membrane resistance and capacitance. The model also predicts resonance at ultrasonic frequencies that is inversely proportional to cell length. These features suggest all mammals use outer hair cell piezoelectricity to support the high-frequency receptor potentials that drive electromotility. It is also possible that members of some mammalian orders use outer hair cell piezoelectric resonance in detecting species-specific vocalizations.

  7. Helmholtz and Goethe -- controversies at the birth of modern neuroscience.

    Science.gov (United States)

    Kesselring, Jürg

    2013-01-01

    Hermann von Helmholtz (1821-1894), a great German scientist and philosopher, made his mark during the exciting twilight period from the Enlightenment and Romanticism to the beginnings of modern neuroscience and offered new perspectives through his work. His early inclination was for physics, which he found more attractive than purely geometric and algebraic studies, but his father was not able to make it possible for him to study physics, and so he studied medicine in order to earn a living. His lecture before the Physical Society in Berlin on July 23, 1847, 'about the conservation of the force' marked an epochal turn, even though his intention had been to deliver 'merely, some critical investigations and arrangement of facts in favor of the physiologists' as well as good arguments for the refusal of the theory of 'vitality'. Even though these new concepts were at first dismissed as fantastic speculation by some of the authorities in physics and philosophy of the day, they were enthusiastically welcomed by younger students of philosophy and the older men soon had to allow themselves to be persuaded that the effectiveness of vitality, though great and beautiful, is actually always dependent on some source of energy. Helmholtz critically assessed Goethe as a physical scientist but he did not dispute his great importance as a poet. Copyright © 2012 S. Karger AG, Basel.

  8. Archive of Geosample Information from the GEOMAR Helmholtz Centre for Ocean Research Kiel Core Repository

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The GEOMAR Helmholtz Centre for Ocean Research Kiel made a one-time contribution to the Index to Marine and Lacustrine Geological Samples (IMLGS) database of...

  9. Density-space potential phase difference in a Kelvin--Helmholtz instability

    International Nuclear Information System (INIS)

    Glowienka, J.C.; Jennings, W.C.; Hickok, R.L.

    1974-01-01

    The low-frequency instability found in a hollow cathode discharge in helium was studied using an ion beam probe as a primary diagnostic tool. Three aspects of the instability are discussed: the location and amplitude of the oscillation and its correlation with the shape of the space potential; the phase angle between density and space potential oscillations; and the comparison of the data with three known instability models: Kelvin--Helmholtz, Rayleigh--Taylor, and drift waves--for mode identification. (U.S.)

  10. Upper Hybrid Resonance of Microwaves with a Large Magnetized Plasma Sheet

    International Nuclear Information System (INIS)

    Huo Wenqing; Guo Shijie; Ding Liang; Xu Yuemin

    2013-01-01

    A large magnetized plasma sheet with size of 60 cm × 60 cm × 2 cm was generated by a linear hollow cathode discharge under the confinement of a uniform magnetic field generated by a Helmholtz Coil. The microwave transmission characteristic of the plasma sheet was measured for different incident frequencies, in cases with the electric field polarization of the incident microwave either perpendicular or parallel to the magnetic field. In this measurement, parameters of the plasma sheet were changed by varying the discharge current and magnetic field intensity. In the experiment, upper hybrid resonance phenomena were observed when the electric field polarization of the incident wave was perpendicular to the magnetic field. These resonance phenomena cannot be found in the case of parallel polarization incidence. This result is consistent with theoretical consideration. According to the resonance condition, the electron density values at the resonance points are calculated under various experimental conditions. This kind of resonance phenomena can be used to develop a specific method to diagnose the electron density of this magnetized plasma sheet apparatus. Moreover, it is pointed out that the operating parameters of the large plasma sheet in practical applications should be selected to keep away from the upper hybrid resonance point to prevent signals from polarization distortion

  11. Characterizing permanent magnet blocks with Helmholtz coils

    Science.gov (United States)

    Carnegie, D. W.; Timpf, J.

    1992-08-01

    Most of the insertion devices to be installed at the Advanced Photon Source will utilize permanent magnets in their magnetic structures. The quality of the spectral output is sensitive to the errors in the field of the device which are related to variations in the magnetic properties of the individual blocks. The Advanced Photon Source will have a measurement facility to map the field in the completed insertion devices and equipment to test and modify the magnetic strength of the individual magnet blocks. One component of the facility, the Helmholtz coil permanent magnet block measurement system, has been assembled and tested. This system measures the total magnetic moment vector of a block with a precision better than 0.01% and a directional resolution of about 0.05°. The design and performance of the system will be presented.

  12. Effect of cold plasma on the Kelvin-Helmholtz instability

    International Nuclear Information System (INIS)

    Melander, B.G.

    1978-01-01

    The thesis studies the effect of a two-component plasma (hot and cold) on the shear driven Kelvin-Helmholtz instability. An ion distribution with a shear flow parallel to the ambient magnetic field and a density gradient parallel to the shear direction is used. Both the electrostatic and electromagnetic versions of the instability are studied in the limit of hydromagnetic frequencies. The dispersion relation is obtained in the electrostatic case by solving the Vlasov equation for the perturbed ion and electron densities and then using the quasineutrality condition. In the electromagnetic case the coupled Vlasov and Maxwell's equations are solved to obtain the dispersion relation

  13. Resonant-frequency discharge in a multi-cell radio frequency cavity

    International Nuclear Information System (INIS)

    Popović, S.; Upadhyay, J.; Nikolić, M.; Vušković, L.; Mammosser, J.

    2014-01-01

    We are reporting experimental results on a microwave discharge operating at resonant frequency in a multi-cell radio frequency (RF) accelerator cavity. Although the discharge operated at room temperature, the setup was constructed so that it could be used for plasma generation and processing in fully assembled active superconducting radio-frequency cryo-module. This discharge offers a mechanism for removal of a variety of contaminants, organic or oxide layers, and residual particulates from the interior surface of RF cavities through the interaction of plasma-generated radicals with the cavity walls. We describe resonant RF breakdown conditions and address the issues related to resonant detuning due to sustained multi-cell cavity plasma. We have determined breakdown conditions in the cavity, which was acting as a plasma vessel with distorted cylindrical geometry. We discuss the spectroscopic data taken during plasma removal of contaminants and use them to evaluate plasma parameters, characterize the process, and estimate the volatile contaminant product removal

  14. Resonant-frequency discharge in a multi-cell radio frequency cavity

    Energy Technology Data Exchange (ETDEWEB)

    Popovic, S; Upadhyay, J; Mammosser, J; Nikolic, M; Vuskovic, L

    2014-11-07

    We are reporting experimental results on microwave discharge operating at resonant frequency in a multi-cell radio frequency (RF) accelerator cavity. Although the discharge operated at room temperature, the setup was constructed so that it could be used for plasma generation and processing in fully assembled active superconducting radio-frequency (SRF) cryomodule (in situ operation). This discharge offers an efficient mechanism for removal of a variety of contaminants, organic or oxide layers, and residual particulates from the interior surface of RF cavities through the interaction of plasma-generated radicals with the cavity walls. We describe resonant RF breakdown conditions and address the problems related to generation and sustaining the multi-cell cavity plasma, which are breakdown and resonant detuning. We have determined breakdown conditions in the cavity, which was acting as a plasma vessel with distorted cylindrical geometry. We discuss the spectroscopic data taken during plasma removal of contaminants and use them to evaluate plasma parameters, characterize the process, and estimate the volatile contaminant product removal.

  15. Optical Pumping Spin Exchange 3He Gas Cells for Magnetic Resonance Imaging

    Science.gov (United States)

    Kim, W.; Stepanyan, S. S.; Kim, A.; Jung, Y.; Woo, S.; Yurov, M.; Jang, J.

    2009-08-01

    We present a device for spin-exchange optical pumping system to produce large quantities of polarized noble gases for Magnetic Resonance Imaging (MRI). A method and design of apparatus for pumping the polarization of noble gases is described. The method and apparatus enable production, storage and usage of hyperpolarized noble gases for different purposes, including Magnetic Resonance Imaging of human and animal subjects. Magnetic imaging agents breathed into lungs can be observed by the radio waves of the MRI scanner and report back physical and functional information about lung's health and desease. The technique known as spin exchange optical pumping is used. Nuclear magnetic resonance is implemented to measure the polarization of hyperpolarized gas. The cells prepared and sealed under high vacuum after handling Alkali metals into the cell and filling with the 3He-N2 mixture. The cells could be refilled. The 3He reaches around 50% polarization in 5-15 hours.

  16. Application of He’s Variational Iteration Method to Nonlinear Helmholtz Equation and Fifth-Order KDV Equation

    DEFF Research Database (Denmark)

    Miansari, Mo; Miansari, Me; Barari, Amin

    2009-01-01

    In this article, He’s variational iteration method (VIM), is implemented to solve the linear Helmholtz partial differential equation and some nonlinear fifth-order Korteweg-de Vries (FKdV) partial differential equations with specified initial conditions. The initial approximations can be freely c...

  17. The Kelvin-Helmholtz instability on the magnetopause

    International Nuclear Information System (INIS)

    Kivelson, M.G.; California Univ., Los Angeles; Pu, Z.-Y.

    1984-01-01

    Conditions for the development of Kelvin-Helmholtz (K-H) waves on the magnetopause have been known for more than 15 years; more recently, spacecraft observations have stimulated further examination of the properties of K-H waves. For a magnetopause with no boundary layer, two different modes of surface waves have been identified and their properties have been investigated for various assumed orientations of magnetic field and flow velocity vectors. The power radiated into the magnetosphere from the velocity shear at the boundary has been estimated. Other calculations have focused on the consequences of finite thickness boundary layers, both uniform and non-uniform. The boundary layer is found to modify the wave modes present at the magnetopause and to yield a criterion for the wavelength of the fastest growing surface waves. The paper concludes by questioning the extent to which the inferences from boundary layer models are model dependent and identifies areas where further work is needed or anticipated. (author)

  18. Shear wave induced resonance elastography of spherical masses with polarized torsional waves

    Science.gov (United States)

    Hadj Henni, Anis; Schmitt, Cédric; Trop, Isabelle; Cloutier, Guy

    2012-03-01

    Shear wave induced resonance (SWIR) is a technique for dynamic ultrasound elastography of confined mechanical inclusions. It was developed for breast tumor imaging and tissue characterization. This method relies on the polarization of torsional shear waves modeled with the Helmholtz equation in spherical coordinates. To validate modeling, an invitro set-up was used to measure and image the first three eigenfrequencies and eigenmodes of a soft sphere. A preliminary invivo SWIR measurement on a breast fibroadenoma is also reported. Results revealed the potential of SWIR elastography to detect and mechanically characterize breast lesions for early cancer detection.

  19. destiny: diffusion maps for large-scale single-cell data in R.

    Science.gov (United States)

    Angerer, Philipp; Haghverdi, Laleh; Büttner, Maren; Theis, Fabian J; Marr, Carsten; Buettner, Florian

    2016-04-15

    : Diffusion maps are a spectral method for non-linear dimension reduction and have recently been adapted for the visualization of single-cell expression data. Here we present destiny, an efficient R implementation of the diffusion map algorithm. Our package includes a single-cell specific noise model allowing for missing and censored values. In contrast to previous implementations, we further present an efficient nearest-neighbour approximation that allows for the processing of hundreds of thousands of cells and a functionality for projecting new data on existing diffusion maps. We exemplarily apply destiny to a recent time-resolved mass cytometry dataset of cellular reprogramming. destiny is an open-source R/Bioconductor package "bioconductor.org/packages/destiny" also available at www.helmholtz-muenchen.de/icb/destiny A detailed vignette describing functions and workflows is provided with the package. carsten.marr@helmholtz-muenchen.de or f.buettner@helmholtz-muenchen.de Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  20. Equation of state and Helmholtz free energy for the atomic system of the repulsive Lennard-Jones particles.

    Science.gov (United States)

    Mirzaeinia, Ali; Feyzi, Farzaneh; Hashemianzadeh, Seyed Majid

    2017-12-07

    Simple and accurate expressions are presented for the equation of state (EOS) and absolute Helmholtz free energy of a system composed of simple atomic particles interacting through the repulsive Lennard-Jones potential model in the fluid and solid phases. The introduced EOS has 17 and 22 coefficients for fluid and solid phases, respectively, which are regressed to the Monte Carlo (MC) simulation data over the reduced temperature range of 0.6≤T * ≤6.0 and the packing fraction range of 0.1 ≤ η ≤ 0.72. The average absolute relative percent deviation in fitting the EOS parameters to the MC data is 0.06 and 0.14 for the fluid and solid phases, respectively. The thermodynamic integration method is used to calculate the free energy using the MC simulation results. The Helmholtz free energy of the ideal gas is employed as the reference state for the fluid phase. For the solid phase, the values of the free energy at the reduced density equivalent to the close-packed of a hard sphere are used as the reference state. To check the validity of the predicted values of the Helmholtz free energy, the Widom particle insertion method and the Einstein crystal technique of Frenkel and Ladd are employed. The results obtained from the MC simulation approaches are well agreed to the EOS results, which show that the proposed model can reliably be utilized in the framework of thermodynamic theories.

  1. Design and first measurements of an alternative calorimetry chamber for the HZB quadrupole resonator

    CERN Document Server

    Keckert, Sebastian; Knobloch, Jens; Kugeler, Oliver

    2015-01-01

    The systematic research on superconducting thin films requires dedicated testing equipment. The Quadrupole Resonator (QPR) is a specialized tool to characterize the superconducting RF properties of circular planar samples. A calorimetric measurement of the RF surface losses allows the surface resistance to be measured with sub nano-ohm resolution. This measurement can be performed over a wide temperature and magnetic field range, at frequencies of 433, 866 and 1300 MHz. The system at Helmholtz-Zentrum Berlin (HZB) is based on a resonator built at CERN and has been optimized to lower peak electric fields and an improved resolution. In this paper the design of an alternative calorimetry chamber is presented, providing flat samples for coating which are easy changeable. All parts are connected by screwing connections and no electron beam welding is required. Furthermore this design enables exchangeability of samples between the resonators at HZB and CERN. First measurements with the new design show ambiguous r...

  2. Ultrasonic transducers with resonant cavities as emitters for air-borne applications

    Directory of Open Access Journals (Sweden)

    Montero De Espinosa Freijo, F.

    2009-08-01

    Full Text Available In this work a new proposal to improve the emission efficiency of air-borne ultrasonic transducers is introduced. A theoretical ultrasonic transducer design is studied using a piezoelectric membrane and a Helmholtz resonator with two acoustic ports. The resonator provides radiation in the acoustic ports in phase with that of the membrane. Several finite element simulations and experimental results are used to study the device. The finite element models were used to compare its behaviour with that of conventional vacuum-cavity transducers. These results show an improvement in the bandwidth reaching a quality factor value of 19. Furthermore, the experimental measurements were used to study the effects of the resonant cavity in the response. Several measurements for different cavity depths were performed. The results show an improvement of 25 dB in the emitted pressure through tuning the transducer.

    En este trabajo se presenta una nueva propuesta para mejorar la eficiencia de transductores ultrasónicos acoplados a aire. Para este estudio se ha empleado un diseño teórico de transductor ultrasónico que utiliza una membrana piezoeléctrica y un resonador de Helmholtz con dos puertos acústicos. El resonador hace que la radiación en los puertos acústicos se encuentre en fase con la producida por la membrana. Para estudiar el dispositivo se utilizaron resultados obtenidos mediante programas de elementos finitos y resultados experimentales. Por un lado, los modelos de elementos finitos se utilizaron para comparar el comportamiento del dispositivo con el de transductores convencionales con cavidades al vacío. Estos resultados indican una mejora en el ancho de banda alcanzando valores de factor de calidad de 19. Por otro lado, los resultados experimentales se emplearon para identificar los efectos de la cavidad resonante en el funcionamiento del dispositivo. Para ello se realizaron varias medidas utilizando ciertas profundidades de cavidad

  3. Severe accident research activities at Helmholtz-Zentrum Dresden-Rossendorf (HZDR)

    Energy Technology Data Exchange (ETDEWEB)

    Wilhelm, Polina; Jobst, Matthias; Schaefer, Frank; Kliem, Soeren [Helmholtz-Zentrum Dresden-Rossendorf e.V., Dresden (Germany)

    2016-05-15

    In the frame of the nuclear safety research program of the Helmholtz Association HZDR performs fundamental and applied research to assess and to reduce the risks related to the nuclear fuel cycle and the production of electricity in nuclear power plants. One of the research topics focuses on the safety aspects of current and future reactor designs. This includes the development and application of methods for analyses of transients and postulated accidents, covering the whole spectrum from normal operation till severe accident sequences including core degradation. This paper gives an overview of the severe accident research activities at the Reactor Safety Division at the Institute of Resource Ecology.

  4. Single cell targeting using plasmon resonant gold-coated liposomes

    Science.gov (United States)

    Leung, Sarah J.; Romanowski, Marek

    2012-03-01

    We have developed an experimental system with the potential for the delivery and localized release of an encapsulated agent with high spatial and temporal resolution. We previously introduced liposome-supported plasmon resonant gold nanoshells; in this composite structure, the liposome allows for the encapsulation of substances, such as therapeutic agents, neurotransmitters, or growth factors, and the plasmon resonant structure facilitates the rapid release of encapsulated contents upon laser light illumination. More recently, we demonstrated that these gold-coated liposomes are capable of releasing their contents in a spectrally-controlled manner, where plasmon resonant nanoparticles only release content upon illumination with a wavelength of light matching their plasmon resonance band. We now show that this release mechanism can be used in a biological setting to deliver a peptide derivative of cholecystokinin to HEK293 cells overexpressing the CCK2 receptor. Using directed laser light, we may enable localized release from gold-coated liposomes to enable accurate perturbation of cellular functions in response to released compounds; this system may have possible applications in signaling pathways and drug discovery.

  5. The use of acoustically tuned resonators to improve the sound transmission loss of double-panel partitions

    Science.gov (United States)

    Mason, J. M.; Fahy, F. J.

    1988-07-01

    Double-leaf partitions are often utilized in situations requiring low weight structures with high transmission loss, an example of current interest being the fuselage walls of propeller-driven aircraft. In this case, acoustic excitation is periodic and, if one of the frequencies of excitation lies in the region of the fundamental mass-air-mass frequency of the partition, insulation performance is considerably less than desired. The potential effectiveness of tuned Helmholtz resonators connected to the partition cavity is investigated as a method of improving transmission loss. This is demonstrated by a simple theoretical model and then experimentally verified. Results show that substantial improvements may be obtained at and around the mass-air-mass frequency for a total resonator volume 15 percent of the cavity volume.

  6. Connecting science and the musical arts in teaching tone quality: Integrating Helmholtz motion and master violin teachers' pedagogies

    Science.gov (United States)

    Collins, Cheri D.

    Is it possible for students to achieve better tone quality from even their factory-made violins? All violins, regardless of cost, have a common capacity for good tone in certain frequencies. These signature modes outline the first position range of a violin (196-600 hertz). To activate this basic capacity of all violins, the string must fully vibrate. To accomplish this the bow must be pulled across the string with enough pressure (relative to its speed and contact point) for the horsehairs to catch. This friction permits the string to vibrate in Helmholtz Motion, which produces a corner that travels along the edge of the string between the bridge and the nut. Creating this corner is the most fundamental technique for achieving good tone. The findings of celebrated scientists Ernest Chladni, Hermann von Helmholtz, and John Schelleng will be discussed and the tone-production pedagogy of master teachers Carl Flesch, Ivan Galamian, Robert Gerle, and Simon Fischer will be investigated. Important connections between the insights of these scientists and master teachers are evident. Integrating science and art can provide teachers with a better understanding of the characteristics of good tone. This can help their students achieve the best possible sound from their instruments. In the private studio the master teacher may not use the words "Helmholtz Motion." Yet through modeling and listening students are able to understand and create a quality tone. Music teachers without experience in string performance may be assigned to teach strings in classroom and ensembles settings. As a result modeling good tone is not always possible. However, all teachers and conductors can understand the fundamental behavior of string vibration and adapt their instruction strategies towards student success. Better tonal quality for any string instrument is ultimately achieved. Mastery and use of the Helmholtz Motion benefits teachers and students alike. Simple practice exercises for teaching

  7. Kelvin-Helmholtz instability for a bounded plasma flow in a longitudinal magnetic field

    International Nuclear Information System (INIS)

    Burinskaya, T. M.; Shevelev, M. M.; Rauch, J.-L.

    2011-01-01

    Kelvin-Helmholtz MHD instability in a plane three-layer plasma is investigated. A general dispersion relation for the case of arbitrarily orientated magnetic fields and flow velocities in the layers is derived, and its solutions for a bounded plasma flow in a longitudinal magnetic field are studied numerically. Analysis of Kelvin-Helmholtz instability for different ion acoustic velocities shows that perturbations with wavelengths on the order of or longer than the flow thickness can grow in an arbitrary direction even at a zero temperature. Oscillations excited at small angles with respect to the magnetic field exist in a limited range of wavenumbers even without allowance for the finite width of the transition region between the flow and the ambient plasma. It is shown that, in a low-temperature plasma, solutions resulting in kink-like deformations of the plasma flow grow at a higher rate than those resulting in quasi-symmetric (sausage-like) deformations. The transverse structure of oscillatory-damped eigenmodes in a low-temperature plasma is analyzed. The results obtained are used to explain mechanisms for the excitation of ultra-low-frequency long-wavelength oscillations propagating along the magnetic field in the plasma sheet boundary layer of the Earth’s magnetotail penetrated by fast plasma flows.

  8. Iterative solution of the Helmholtz equation

    Energy Technology Data Exchange (ETDEWEB)

    Larsson, E.; Otto, K. [Uppsala Univ. (Sweden)

    1996-12-31

    We have shown that the numerical solution of the two-dimensional Helmholtz equation can be obtained in a very efficient way by using a preconditioned iterative method. We discretize the equation with second-order accurate finite difference operators and take special care to obtain non-reflecting boundary conditions. We solve the large, sparse system of equations that arises with the preconditioned restarted GMRES iteration. The preconditioner is of {open_quotes}fast Poisson type{close_quotes}, and is derived as a direct solver for a modified PDE problem.The arithmetic complexity for the preconditioner is O(n log{sub 2} n), where n is the number of grid points. As a test problem we use the propagation of sound waves in water in a duct with curved bottom. Numerical experiments show that the preconditioned iterative method is very efficient for this type of problem. The convergence rate does not decrease dramatically when the frequency increases. Compared to banded Gaussian elimination, which is a standard solution method for this type of problems, the iterative method shows significant gain in both storage requirement and arithmetic complexity. Furthermore, the relative gain increases when the frequency increases.

  9. Surface plasmon resonance sensing: from purified biomolecules to intact cells.

    Science.gov (United States)

    Su, Yu-Wen; Wang, Wei

    2018-04-12

    Surface plasmon resonance (SPR) has become a well-recognized label-free technique for measuring the binding kinetics between biomolecules since the invention of the first SPR-based immunosensor in 1980s. The most popular and traditional format for SPR analysis is to monitor the real-time optical signals when a solution containing ligand molecules is flowing over a sensor substrate functionalized with purified receptor molecules. In recent years, rapid development of several kinds of SPR imaging techniques have allowed for mapping the dynamic distribution of local mass density within single living cells with high spatial and temporal resolutions and reliable sensitivity. Such capability immediately enabled one to investigate the interaction between important biomolecules and intact cells in a label-free, quantitative, and single cell manner, leading to an exciting new trend of cell-based SPR bioanalysis. In this Trend Article, we first describe the principle and technical features of two types of SPR imaging techniques based on prism and objective, respectively. Then we survey the intact cell-based applications in both fundamental cell biology and drug discovery. We conclude the article with comments and perspectives on the future developments. Graphical abstract Recent developments in surface plasmon resonance (SPR) imaging techniques allow for label-free mapping the mass-distribution within single living cells, leading to great expansions in biomolecular interactions studies from homogeneous substrates functionalized with purified biomolecules to heterogeneous substrates containing individual living cells.

  10. Of the Helmholtz Club, South-Californian seedbed for visual and cognitive neuroscience, and its patron Francis Crick.

    Science.gov (United States)

    Aicardi, Christine

    2014-03-01

    Taking up the view that semi-institutional gatherings such as clubs, societies, research schools, have been instrumental in creating sheltered spaces from which many a 20th-century project-driven interdisciplinary research programme could develop and become established within the institutions of science, the paper explores the history of one such gathering from its inception in the early 1980s into the 2000s, the Helmholtz Club, which brought together scientists from such various research fields as neuroanatomy, neurophysiology, psychophysics, computer science and engineering, who all had an interest in the study of the visual system and of higher cognitive functions relying on visual perception such as visual consciousness. It argues that British molecular biologist turned South Californian neuroscientist Francis Crick had an early and lasting influence over the Helmholtz Club of which he was a founding pillar, and that from its inception, the club served as a constitutive element in his long-term plans for a neuroscience of vision and of cognition. Further, it argues that in this role, the Helmholtz Club served many purposes, the primary of which was to be a social forum for interdisciplinary discussion, where 'discussion' was not mere talk but was imbued with an epistemic value and as such, carefully cultivated. Finally, it questions what counts as 'doing science' and in turn, definitions of success and failure-and provides some material evidence towards re-appraising the successfulness of Crick's contribution to the neurosciences. Copyright © 2013 The Author. Published by Elsevier Ltd.. All rights reserved.

  11. Development of a Miniature, Two-Axis, Triple-Helmholtz-Driven Gimbal

    Science.gov (United States)

    Sharif, Boz; Joscelyn, Ed; Wilcox, Brian; Johnson, Michael R.

    2000-01-01

    This paper details the development of a Helmholtz-driven, 2-axis gimbal to position a flat mirror within 50 microradian (fine positioning) in a space environment. The gimbal is intended to travel on a deep space mission mounted on a miniature "rover" vehicle. The gimbal will perform both pointing and scanning functions. The goal for total mass of the gimbal was 25 grams. The primary challenge was to design and build a bearing system that would achieve the required accuracy in addition to supporting the relatively large mass of the mirror and the outer gimbal. The mechanism is subjected to 100-G loading without the aid of any additional caging mechanism. Additionally, it was desired to have the same level of accuracy during Earth-bound, 1-G testing. Due to the inherent lack of damping in a zero-G, vacuum environment; the ability of the gimbal to respond to very small amounts of input energy is paramount. Initial testing of the first prototype revealed exceedingly long damping times required even while exposed to the damping effects of air and 1-G friction. It is envisioned that fine positioning of the gimbal will be accomplished in very small steps to avoid large disturbances to the mirror. Various bearing designs, including materials, lubrication options and bearing geometry will be discussed. In addition various options for the Helmholtz coil design will be explored with specific test data given. Ground testing in the presence of 1-G was compounded by the local magnetic fields due to the "compass" effect on the gimbal. The test data will be presented and discussed. Additionally, rationale for estimating gimbal performance in a zero-G environment will be presented and discussed.

  12. The evolution of air resonance power efficiency in the violin and its ancestors.

    Science.gov (United States)

    Nia, Hadi T; Jain, Ankita D; Liu, Yuming; Alam, Mohammad-Reza; Barnas, Roman; Makris, Nicholas C

    2015-03-08

    The fact that acoustic radiation from a violin at air-cavity resonance is monopolar and can be determined by pure volume change is used to help explain related aspects of violin design evolution. By determining the acoustic conductance of arbitrarily shaped sound holes, it is found that air flow at the perimeter rather than the broader sound-hole area dominates acoustic conductance, and coupling between compressible air within the violin and its elastic structure lowers the Helmholtz resonance frequency from that found for a corresponding rigid instrument by roughly a semitone. As a result of the former, it is found that as sound-hole geometry of the violin's ancestors slowly evolved over centuries from simple circles to complex f-holes, the ratio of inefficient, acoustically inactive to total sound-hole area was decimated, roughly doubling air-resonance power efficiency. F-hole length then slowly increased by roughly 30% across two centuries in the renowned workshops of Amati, Stradivari and Guarneri, favouring instruments with higher air-resonance power, through a corresponding power increase of roughly 60%. By evolution-rate analysis, these changes are found to be consistent with mutations arising within the range of accidental replication fluctuations from craftsmanship limitations with subsequent selection favouring instruments with higher air-resonance power.

  13. Spectrophotometric investigations of He-I/II resonance emissions with a rocket-borne multisensor resonance cell instrumentation

    International Nuclear Information System (INIS)

    Lay, G.; Fahr, H.J.; Wulf-Mathies, C.

    1980-01-01

    Terrestrial and extraterrestrial resonance emissions of neutral and ionized helium have been observed by means of a multiresonance cell device on board a Skylark 12 rocket. Results obtained during a successful rocket flight on October 12, 1979, from Natal, Brazil, are shown, and a preliminary data analysis is given. (Auth.)

  14. Far off-resonance laser frequency stabilization using multipass cells in Faraday rotation spectroscopy.

    Science.gov (United States)

    Quan, Wei; Li, Yang; Li, Rujie; Shang, Huining; Fang, Zishan; Qin, Jie; Wan, Shuangai

    2016-04-01

    We propose a far off-resonance laser frequency stabilization method by using multipass cells in Rb Faraday rotation spectroscopy. Based on the detuning equation, if multipass cells with several meters optical path length are used in the conventional Faraday spectroscopy, the detuning of the lock point can be extended much further from the alkali metal resonance. A plate beam splitter was used to generate two different Faraday signals at the same time. The transmitted optical path length was L=50  mm and the reflected optical path length was 2L=100  mm. When the optical path length doubled, the detuning of the lock points moved further away from the atomic resonance. The temperature dependence of the detuning of the lock point was also analyzed. A temperature-insensitive lock point was found near resonance when the cell temperature was between 110°C and 130°C. We achieved an rms fluctuation of 0.9 MHz/23 h at a detuning of 0.5 GHz. A frequency drift of 16 MHz/h at a detuning of -5.6  GHz and 4 MHz/h at a detuning of -5.2  GHz were also obtained for the transmitted and reflected light Faraday signal.

  15. Numerical solution of an inverse 2D Cauchy problem connected with the Helmholtz equation

    International Nuclear Information System (INIS)

    Wei, T; Qin, H H; Shi, R

    2008-01-01

    In this paper, the Cauchy problem for the Helmholtz equation is investigated. By Green's formulation, the problem can be transformed into a moment problem. Then we propose a numerical algorithm for obtaining an approximate solution to the Neumann data on the unspecified boundary. Error estimate and convergence analysis have also been given. Finally, we present numerical results for several examples and show the effectiveness of the proposed method

  16. Enhancing DC Glow Discharge Tube Museuum Displays using a Theremin Controlled Helmholtz Coil to Demonstrate Magnetic Confinement

    Science.gov (United States)

    Siu, Theodore; Wissel, Stephanie; Guttadora, Larry; Liao, Susan; Zwicker, Andrew

    2010-11-01

    Since their discovery in the mid 1800's, DC glow discharge apparatuses have commonly been used for spectral analysis, the demonstration of the Frank-Hertz experiment, and to study plasma breakdown voltages following from the Paschen Curve. A DC glow discharge tube museum display was outfitted with a Helmholtz Coil electromagnet in order to demonstrate magnetic confinement for a science museum display. A device commonly known as a ``theremin'' was designed and built in order to externally control the Helmholtz Coil current and the plasma current. Originally a musical instrument, a theremin has two variable capacitors connected to two radio frequency oscillators which determine pitch and volume. Using a theremin to control current and ``play'' the plasma adds appeal and durability by providing a new innovative means of interacting with a museum exhibit. Educationally, students can use the display to not only learn about plasma properties but also electronic properties of the human body.

  17. Kelvin-Helmholtz instability: the ``atom'' of geophysical turbulence?

    Science.gov (United States)

    Smyth, William

    2017-11-01

    Observations of small-scale turbulence in Earth's atmosphere and oceans have most commonly been interpreted in terms of the Kolmogorov theory of isotropic turbulence, despite the fact that the observed turbulence is significantly anisotropic due to density stratification and sheared large-scale flows. I will describe an alternative picture in which turbulence consists of distinct events that occur sporadically in space and time. The simplest model for an individual event is the ``Kelvin-Helmholtz (KH) ansatz'', in which turbulence relieves the dynamic instability of a localized shear layer. I will summarize evidence that the KH ansatz is a valid description of observed turbulence events, using microstructure measurements from the equatorial Pacific ocean as an example. While the KH ansatz has been under study for many decades and is reasonably well understood, the bigger picture is much less clear. How are the KH events distributed in space and time? How do different events interact with each other? I will describe some tentative steps toward a more thorough understanding.

  18. Expression of Heat Shock Proteins in Human Fibroblast Cells under Magnetic Resonant Coupling Wireless Power Transfer

    Directory of Open Access Journals (Sweden)

    Kohei Mizuno

    2015-10-01

    Full Text Available Since 2007, resonant coupling wireless power transfer (WPT technology has been attracting attention and has been widely researched for practical use. Moreover, dosimetric evaluation has also been discussed to evaluate the potential health risks of the electromagnetic field from this WPT technology based on the International Commission on Non-Ionizing Radiation Protection (ICNIRP guidelines. However, there has not been much experimental evaluation of the potential health risks of this WPT technology. In this study, to evaluate whether magnetic resonant coupling WPT induces cellular stress, we focused on heat shock proteins (Hsps and determined the expression level of Hsps 27, 70 and 90 in WI38VA13 subcloned 2RA human fibroblast cells using a western blotting method. The expression level of Hsps under conditions of magnetic resonant coupling WPT for 24 h was not significantly different compared with control cells, although the expression level of Hsps for cells exposed to heat stress conditions was significantly increased. These results suggested that exposure to magnetic resonant coupling WPT did not cause detectable cell stress.

  19. Integrability and symmetries for the Helmholtz oscillator with friction

    International Nuclear Information System (INIS)

    Almendral, Juan A; Sanjuan, Miguel A F

    2003-01-01

    This paper deals with the Helmholtz oscillator, which is a simple nonlinear oscillator whose equation presents a quadratic nonlinearity and the possibility of escape. When a periodic external force is introduced, the width of the stochastic layer, which is a region around the separatrix where orbits may exhibit transient chaos, is calculated. In the absence of friction and external force, it is well known that analytical solutions exist since it is completely integrable. When only friction is included, there is no analytical solution for all parameter values. However, by means of the Lie theory for differential equations we find a relation between parameters for which the oscillator is integrable. This is related to the fact that the system possesses a symmetry group and the corresponding symmetries are computed. Finally, the analytical explicit solutions are shown and related to the basins of attraction

  20. Kelvin-Helmholtz instability and kinetic internal kink modes in tokamaks

    International Nuclear Information System (INIS)

    Naitou, H.

    2002-01-01

    The m=1 and n=1 kinetic internal kink (KIK) mode with a nonuniform density profile is studied by the cylindrical version of the gyro-reduced-MHD code which is one of the extended MHD codes being able to treat the physics beyond resistive MHD. Electron inertia and electron finite temperature effects are crucial. The linear mode structure of KIK mode includes the sheared poloidal flow with m=1, which excites the vortexes due to the Kelvin-Helmholtz (K-H) instability. We have found that there is a strong coupling between the KIK mode and the K-H mode even in the early nonlinear stage of KIK instability in which the width of the m=1 magnetic island is sufficiently small. (author)

  1. Resonance ionization in a gas cell: a feasibility study for a laser ion source

    International Nuclear Information System (INIS)

    Qamhieh, Z.N.; Vandeweert, E.; Silverans, R.E.; Duppen, P. van; Huyse, M.; Vermeeren, L.

    1992-01-01

    A laser ion source based on resonance photo-ionization in a gas cell is proposed. The gas cell, filled with helium, consists of a target chamber in which the recoil products are stopped and neutralized, and an ionization chamber where the atoms of interest are selectively ionized by the laser light. The extraction of the ions from the ionization chamber through the exit hole-skimmer setup is similar to the ion-guide system. The conditions to obtain an optimal system are given. The results of a two-step one-laser resonance photo-ionization of nickel and the first results of laser ionization in a helium buffer gas cell are presented. (orig.)

  2. Novel approach to the Helmholtz integral equation solution by Fourier series expansion for acoustic radiation and scattering problems

    CSIR Research Space (South Africa)

    Shatalov, MY

    2006-01-01

    Full Text Available -scale structure to guarantee the numerical accuracy of solution. In the present paper the authors propose to use a novel method of solution of the Helmholtz integral equation, which is based on expansion of the integrands in double Fourier series. The main...

  3. On Riemann boundary value problems for null solutions of the two dimensional Helmholtz equation

    Science.gov (United States)

    Bory Reyes, Juan; Abreu Blaya, Ricardo; Rodríguez Dagnino, Ramón Martin; Kats, Boris Aleksandrovich

    2018-01-01

    The Riemann boundary value problem (RBVP to shorten notation) in the complex plane, for different classes of functions and curves, is still widely used in mathematical physics and engineering. For instance, in elasticity theory, hydro and aerodynamics, shell theory, quantum mechanics, theory of orthogonal polynomials, and so on. In this paper, we present an appropriate hyperholomorphic approach to the RBVP associated to the two dimensional Helmholtz equation in R^2 . Our analysis is based on a suitable operator calculus.

  4. KELVIN-HELMHOLTZ INSTABILITY OF A CORONAL STREAMER

    Energy Technology Data Exchange (ETDEWEB)

    Feng, L.; Gan, W. Q. [Key Laboratory of Dark Matter and Space Astronomy, Purple Mountain Observatory, Chinese Academy of Sciences, 210008 Nanjing (China); Inhester, B., E-mail: lfeng@pmo.ac.cn [Max-Planck-Institut fuer Sonnensystemforschung, Max-Planck-Str.2, D-37191 Katlenburg-Lindau (Germany)

    2013-09-10

    Shear-flow-driven instability can play an important role in energy transfer processes in coronal plasma. We present for the first time the observation of a kink-like oscillation of a streamer that is probably caused by the streaming kink-mode Kelvin-Helmholtz instability (KHI). The wave-like behavior of the streamer was observed by the Large Angle and Spectrometric Coronagraph Experiment C2 and C3 on board the SOlar and Heliospheric Observatory. The observed wave had a period of about 70-80 minutes, and its wavelength increased from 2 R{sub Sun} to 3 R{sub Sun} in about 1.5 hr. The phase speeds of its crests and troughs decreased from 406 {+-} 20 to 356 {+-} 31 km s{sup -1} during the event. Within the same heliocentric range, the wave amplitude also appeared to increase with time. We attribute the phenomena to the MHD KHI, which occurs at a neutral sheet in a fluid wake. The free energy driving the instability is supplied by the sheared flow and sheared magnetic field across the streamer plane. The plasma properties of the local environment of the streamer were estimated from the phase speed and instability threshold criteria.

  5. A Cell-to-Cell Equalizer Based on Three-Resonant-State Switched-Capacitor Converters for Series-Connected Battery Strings

    Directory of Open Access Journals (Sweden)

    Yunlong Shang

    2017-02-01

    Full Text Available Due to the low cost, small size, and ease of control, the switched-capacitor (SC battery equalizers are promising among active balancing methods. However, it is difficult to achieve the full cell equalization for the SC equalizers due to the inevitable voltage drops across Metal-Oxide-Semiconductor Field Effect Transistor (MOSFET switches. Moreover, when the voltage gap among cells is larger, the balancing efficiency is lower, while the balancing speed becomes slower as the voltage gap gets smaller. In order to soften these downsides, this paper proposes a cell-to-cell battery equalization topology with zero-current switching (ZCS and zero-voltage gap (ZVG among cells based on three-resonant-state SC converters. Based on the conventional inductor-capacitor (LC converter, an additional resonant path is built to release the charge of the capacitor into the inductor in each switching cycle, which lays the foundations for obtaining ZVG among cells, improves the balancing efficiency at a large voltage gap, and increases the balancing speed at a small voltage gap. A four-lithium-ion-cell prototype is applied to validate the theoretical analysis. Experiment results demonstrate that the proposed topology has good equalization performances with fast equalization, ZCS, and ZVG among cells.

  6. Sub-terahertz resonance spectroscopy of biological macromolecules and cells

    Science.gov (United States)

    Globus, Tatiana; Moyer, Aaron; Gelmont, Boris; Khromova, Tatyana; Sizov, Igor; Ferrance, Jerome

    2013-05-01

    Recently we introduced a Sub-THz spectroscopic system for characterizing vibrational resonance features from biological materials. This new, continuous-wave, frequency-domain spectroscopic sensor operates at room temperature between 315 and 480 GHz with spectral resolution of at least 1 GHz and utilizes the source and detector components from Virginia Diode, Inc. In this work we present experimental results and interpretation of spectroscopic signatures from bacterial cells and their biological macromolecule structural components. Transmission and absorption spectra of the bacterial protein thioredoxin, DNA and lyophilized cells of Escherichia coli (E. coli), as well as spores of Bacillus subtillis and B. atrophaeus have been characterized. Experimental results for biomolecules are compared with absorption spectra calculated using molecular dynamics simulation, and confirm the underlying physics for resonance spectroscopy based on interactions between THz radiation and vibrational modes or groups of modes of atomic motions. Such interactions result in multiple intense and narrow specific resonances in transmission/absorption spectra from nano-gram samples with spectral line widths as small as 3 GHz. The results of this study indicate diverse relaxation dynamic mechanisms relevant to sub-THz vibrational spectroscopy, including long-lasting processes. We demonstrate that high sensitivity in resolved specific absorption fingerprints provides conditions for reliable detection, identification and discrimination capability, to the level of strains of the same bacteria, and for monitoring interactions between biomaterials and reagents in near real-time. Additionally, it creates the basis for the development of new types of advanced biological sensors through integrating the developed system with a microfluidic platform for biomaterial samples.

  7. Enhanced Electron Photoemission by Collective Lattice Resonances in Plasmonic Nanoparticle-Array Photodetectors and Solar Cells

    DEFF Research Database (Denmark)

    Zhukovsky, Sergei; Babicheva, Viktoriia; Uskov, Alexander

    2014-01-01

    We propose to use collective lattice resonances in plasmonic nanoparticle arrays to enhance and tailor photoelectron emission in Schottky barrier photodetectors and solar cells. We show that the interaction between narrow-band lattice resonances (the Rayleigh anomaly) and broader-band individual-particle...... excitations (localized surface plasmon resonances) leads to stronger local field enhancement. In turn, this causes a significant increase of the photocurrent compared to the case when only individual-particle excitations are present. The results can be used to design new photodetectors with highly selective......, tunable spectral response, which are able to detect photons with the energy below the semiconductor bandgap. The findings can also be used to develop solar cells with increased efficiency....

  8. Nonlinear evolution of the magnetized Kelvin-Helmholtz instability: From fluid to kinetic modeling

    Czech Academy of Sciences Publication Activity Database

    Henri, P.; Cerri, S.S.; Califano, F.; Pegoraro, F.; Rossi, C.; Faganello, M.; Šebek, Ondřej; Trávníček, Pavel M.; Hellinger, Petr; Frederiksen, J. T.; Nordlund, A.; Markidis, S.; Keppens, R.; Lapenta, G.

    2013-01-01

    Roč. 20, č. 10 (2013), 102118/1-102118/13 ISSN 1070-664X R&D Projects: GA MŠk(CZ) 7E11053 EU Projects: European Commission(XE) 263340 - SWIFF Grant - others:European Commission(XE) HPC-EUROPA2 - No. 228398; EU(XE) RI-283493; NASA (US) NNX11A1164G Institutional support: RVO:67985815 ; RVO:68378289 Keywords : Kelvin-Helmholtz instability * plasma kinetic theory * plasma magnetohydrodynamics Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics; BL - Plasma and Gas Discharge Physics (UFA-U) Impact factor: 2.249, year: 2013

  9. Resonant cavity enhanced light harvesting in flexible thin-film organic solar cells

    KAUST Repository

    Sergeant, Nicholas P.

    2013-04-24

    Dielectric/metal/dielectric (DMD) electrodes have the potential to significantly increase the absorption efficiency and photocurrent in flexible organic solar cells. We demonstrate that this enhancement is attributed to a broadband cavity resonance. Silver-based semitransparent DMD electrodes with sheet resistances below 10 ohm/sq. are fabricated on flexible polyethylene terephthalate (PET) substrates in a high-throughput roll-to-roll sputtering tool. We carefully study the effect of the semitransparent DMD electrode (here composed of ZnxSnyOz/Ag/InxSn yOz) on the optical device performance of a copper phthalocyanine (CuPc)/fullerene (C60) bilayer cell and illustrate that a resonant cavity enhanced light trapping effect dominates the optical behavior of the device. © 2013 Optical Society of America.

  10. Applying the Helmholtz Illusion to Fashion: Horizontal Stripes Won't Make You Look Fatter

    Directory of Open Access Journals (Sweden)

    Peter Thompson

    2011-01-01

    Full Text Available A square composed of horizontal lines appears taller and narrower than an identical square made up of vertical lines. Reporting this illusion, Hermann von Helmholtz noted that such illusions, in which filled space seems to be larger than unfilled space, were common in everyday life, adding the observation that ladies' frocks with horizontal stripes make the figure look taller. As this assertion runs counter to modern popular belief, we have investigated whether vertical or horizontal stripes on clothing should make the wearer appear taller or fatter. We find that a rectangle of vertical stripes needs to be extended by 7.1% vertically to match the height of a square of horizontal stripes and that a rectangle of horizontal stripes must be made 4.5% wider than a square of vertical stripes to match its perceived width. This illusion holds when the horizontal or vertical lines are on the dress of a line drawing of a woman. We have examined the claim that these effects apply only for 2-dimensional figures in an experiment with 3-D cylinders and find no support for the notion that horizontal lines would be ‘fattening’ on clothes. Significantly, the illusion persists when the horizontal or vertical lines are on pictures of a real half-body mannequin viewed stereoscopically. All the evidence supports Helmholtz's original assertion.

  11. MESSENGER Orbital Observations of Large-Amplitude Kelvin-Helmholtz Waves at Mercury's Magnetopause

    Science.gov (United States)

    Sundberg, Torbjorn; Boardsen, Scott A.; Slavin, James A.; Anderson, Brian J.; Korth, Haje; Zurbuchen, Thomas H.; Raines, Jim M.; Solomon, Sean C.

    2012-01-01

    We present a survey of Kelvi\\ n-Helmholtz (KH) waves at Mercury's magnetopause during MESSENGER's first Mercury year in orb it. The waves were identified on the basis of the well-established sawtooth wave signatures that are associated with non-linear KH vortices at the magnetopause. MESSENGER frequently observed such KH waves in the dayside region of the magnetosphere where the magnetosheath flow velocity is still sub -sonic, which implies that instability growth rates at Mercury's magnetopau are much larger than at Earth. We attribute these greater rates to the limited wave energy dissipation in Mercury's highly resistive regolith. The wave amplitude was often on the order of ' 00 nT or more, and the wave periods were - 10- 20 s. A clear dawn-dusk asymmetry is present in the data, in that all of the observed wave events occurred in the post-noon and dusk-side sectors of the magnetopause. This asymmetry is like ly related to finite Larmor-radius effects and is in agreement with results from particle-in-cell simulations of the instability. The waves were observed almost exclusively during periods when the north-south component of the magnetosheath magnetic field was northward, a pattern similar to that for most terrestrial KH wave events. Accompanying plasma measurements show that the waves were associated with the transport of magnetosheath plasma into the magnetosphere.

  12. Acoustic absorption behaviour of an open-celled aluminium foam

    International Nuclear Information System (INIS)

    Han Fusheng; Seiffert, Gary; Zhao Yuyuan; Gibbs, Barry

    2003-01-01

    Metal foams, especially close-celled foams, are generally regarded as poor sound absorbers. This paper studies the sound absorption behaviour of the open-celled Al foams manufactured by the infiltration process, and the mechanisms involved. The foams show a significant improvement in sound absorption compared with close-celled Al foams, because of their high flow resistance. The absorption performance can be further enhanced, especially at low frequencies, if the foam panel is backed by an appropriate air gap. Increasing the air-gap depth usually increases both the height and the width of the absorption peak and shifts the peak towards lower frequencies. The foam samples with the smallest pore size exhibit the best absorption capacities when there is no air gap, whereas those with medium pore sizes have the best overall performance when there is an air gap. The typical maximum absorption coefficient, noise reduction coefficient and half-width of the absorption peak are 0.96-0.99, 0.44-0.62 and 1500-3500 Hz, respectively. The sound dissipation mechanisms in the open-celled foams are principally viscous and thermal losses when there is no air-gap backing and predominantly Helmholtz resonant absorption when there is an air-gap backing

  13. A Parallel Sweeping Preconditioner for Heterogeneous 3D Helmholtz Equations

    KAUST Repository

    Poulson, Jack

    2013-05-02

    A parallelization of a sweeping preconditioner for three-dimensional Helmholtz equations without large cavities is introduced and benchmarked for several challenging velocity models. The setup and application costs of the sequential preconditioner are shown to be O(γ2N4/3) and O(γN logN), where γ(ω) denotes the modestly frequency-dependent number of grid points per perfectly matched layer. Several computational and memory improvements are introduced relative to using black-box sparse-direct solvers for the auxiliary problems, and competitive runtimes and iteration counts are reported for high-frequency problems distributed over thousands of cores. Two open-source packages are released along with this paper: Parallel Sweeping Preconditioner (PSP) and the underlying distributed multifrontal solver, Clique. © 2013 Society for Industrial and Applied Mathematics.

  14. Kelvin-Helmholtz instability in a bounded plasma flow

    International Nuclear Information System (INIS)

    Burinskaya, T. M.

    2008-01-01

    Kelvin-Helmholtz instability in a three-layer plane geometry is investigated theoretically. It is shown that, in a three-layer system (in contrast to the traditionally considered case in which instability develops at the boundary between two plasma flows), instability can develop at an arbitrary ratio of the plasma flow velocity to the ion-acoustic velocity. Perturbations with wavelengths on the order of the flow thickness or longer can increase even at a zero temperature. The system can also be unstable against long-wavelength perturbations if the flow velocity at one of the boundaries is lower than the sum of the Alfven velocities in the flow and the ambient plasma. The possibility of applying the results obtained to interpret the experimental data acquired in the framework of the CLUSTER multisatellite project is discussed. It follows from these data that, in many cases, the propagation of an accelerated particle flow in the plasma-sheet boundary layer of the Earth's magnetotail is accompanied by the generation of magnetic field oscillations propagating with a velocity on the order of the local Alfven velocity.

  15. ASTEM, Evaluation of Gibbs, Helmholtz and Saturation Line Function for Thermodynamics Calculation

    International Nuclear Information System (INIS)

    Moore, K.V.; Burgess, M.P.; Fuller, G.L.; Kaiser, A.H.; Jaeger, D.L.

    1974-01-01

    1 - Description of problem or function: ASTEM is a modular set of FORTRAN IV subroutines to evaluate the Gibbs, Helmholtz, and saturation line functions as published by the American Society of Mechanical Engineers (1967). Any thermodynamic quantity including derivative properties can be obtained from these routines by a user-supplied main program. PROPS is an auxiliary routine available for the IBM360 version which makes it easier to apply the ASTEM routines to power station models. 2 - Restrictions on the complexity of the problem: Unless re-dimensioned by the user, the highest derivative allowed is order 9. All arrays within ASTEM are one-dimensional to save storage area

  16. A comparison of high-order polynomial and wave-based methods for Helmholtz problems

    Science.gov (United States)

    Lieu, Alice; Gabard, Gwénaël; Bériot, Hadrien

    2016-09-01

    The application of computational modelling to wave propagation problems is hindered by the dispersion error introduced by the discretisation. Two common strategies to address this issue are to use high-order polynomial shape functions (e.g. hp-FEM), or to use physics-based, or Trefftz, methods where the shape functions are local solutions of the problem (typically plane waves). Both strategies have been actively developed over the past decades and both have demonstrated their benefits compared to conventional finite-element methods, but they have yet to be compared. In this paper a high-order polynomial method (p-FEM with Lobatto polynomials) and the wave-based discontinuous Galerkin method are compared for two-dimensional Helmholtz problems. A number of different benchmark problems are used to perform a detailed and systematic assessment of the relative merits of these two methods in terms of interpolation properties, performance and conditioning. It is generally assumed that a wave-based method naturally provides better accuracy compared to polynomial methods since the plane waves or Bessel functions used in these methods are exact solutions of the Helmholtz equation. Results indicate that this expectation does not necessarily translate into a clear benefit, and that the differences in performance, accuracy and conditioning are more nuanced than generally assumed. The high-order polynomial method can in fact deliver comparable, and in some cases superior, performance compared to the wave-based DGM. In addition to benchmarking the intrinsic computational performance of these methods, a number of practical issues associated with realistic applications are also discussed.

  17. Semi-analytical model for hollow-core anti-resonant fibers

    Directory of Open Access Journals (Sweden)

    Wei eDing

    2015-03-01

    Full Text Available We detailedly describe a recently-developed semi-analytical method to quantitatively calculate light transmission properties of hollow-core anti-resonant fibers (HC-ARFs. Formation of equiphase interface at fiber’s outermost boundary and outward light emission ruled by Helmholtz equation in fiber’s transverse plane constitute the basis of this method. Our semi-analytical calculation results agree well with those of precise simulations and clarify the light leakage dependences on azimuthal angle, geometrical shape and polarization. Using this method, we show investigations on HC-ARFs having various core shapes (e.g. polygon, hypocycloid with single- and multi-layered core-surrounds. The polarization properties of ARFs are also studied. Our semi-analytical method provides clear physical insights into the light guidance in ARF and can play as a fast and useful design aid for better ARFs.

  18. Simulation of a quadrupole resonator

    Energy Technology Data Exchange (ETDEWEB)

    Kleindienst, Raphael [Helmholtz Zentrum Berlin (Germany)

    2013-07-01

    Modern particle accelerators often rely on superconducting radio frequency (SRF) technology for accelerating cavities. In particular in CW operation, very high quality factors up into the high range are desirable, since one of the main cost drivers of such an accelerator, the cryogenic refrigeration plant, is inversely proportional to Q{sub 0}. Present day superconducting cavities are generally made of solid Niobium. A possibility to increase the quality factor as well as accelerating fields is to use thin film coated cavities. Apart from Niobium thin films, other superconducting materials, such as MgB{sub 2}, NbN and Nb{sub 3}Sn are promising candidates. Measuring and understanding the RF-properties of superconducting thin films, specifically the surface resistance, is needed to drive forward this development. Currently only few facilities exist capable of measuring the surface resistance of thin films samples with a resolution in the nano-ohm range at the operating frequency of typical cavities(e.g. L-band). A dedicated test stand consisting of a quadrupole resonator is therefore being constructed at the Helmholtz Zentrum Berlin. This system is based on the 400 MHz quadrupole resonator at CERN, with the design adapted to 433 MHz (making available the higher harmonic mode at 1.3 GHz) and optimized with respect to resolution and maximum achievable fields using simulation data obtained with CST Microwave Studio as well as ANSYS. The simulated design is being manufactured. An outlook for future physics runs is given.

  19. Inverse Stochastic Resonance in Cerebellar Purkinje Cells.

    Directory of Open Access Journals (Sweden)

    Anatoly Buchin

    2016-08-01

    Full Text Available Purkinje neurons play an important role in cerebellar computation since their axons are the only projection from the cerebellar cortex to deeper cerebellar structures. They have complex internal dynamics, which allow them to fire spontaneously, display bistability, and also to be involved in network phenomena such as high frequency oscillations and travelling waves. Purkinje cells exhibit type II excitability, which can be revealed by a discontinuity in their f-I curves. We show that this excitability mechanism allows Purkinje cells to be efficiently inhibited by noise of a particular variance, a phenomenon known as inverse stochastic resonance (ISR. While ISR has been described in theoretical models of single neurons, here we provide the first experimental evidence for this effect. We find that an adaptive exponential integrate-and-fire model fitted to the basic Purkinje cell characteristics using a modified dynamic IV method displays ISR and bistability between the resting state and a repetitive activity limit cycle. ISR allows the Purkinje cell to operate in different functional regimes: the all-or-none toggle or the linear filter mode, depending on the variance of the synaptic input. We propose that synaptic noise allows Purkinje cells to quickly switch between these functional regimes. Using mutual information analysis, we demonstrate that ISR can lead to a locally optimal information transfer between the input and output spike train of the Purkinje cell. These results provide the first experimental evidence for ISR and suggest a functional role for ISR in cerebellar information processing.

  20. Polymer-Polymer Förster Resonance Energy Transfer Significantly Boosts the Power Conversion Efficiency of Bulk-Heterojunction Solar Cells.

    Science.gov (United States)

    Gupta, Vinay; Bharti, Vishal; Kumar, Mahesh; Chand, Suresh; Heeger, Alan J

    2015-08-01

    Optically resonant donor polymers can exploit a wider range of the solar spectrum effectively without a complicated tandem design in an organic solar cell. Ultrafast Förster resonance energy transfer (FRET) in a polymer-polymer system that significantly improves the power conversion efficiency in bulk heterojunction polymer solar cells from 6.8% to 8.9% is demonstrated, thus paving the way to achieving 15% efficient solar cells. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Decay of MHD-scale Kelvin-Helmholtz vortices mediated by parasitic electron dynamics

    International Nuclear Information System (INIS)

    Nakamura, T.K.M.; Hayashi, D.; Fujimoto, M.; Shinohara, I.

    2004-01-01

    We have simulated nonlinear development of MHD-scale Kelvin-Helmholtz (KH) vortices by a two-dimensional two-fluid system including finite electron inertial effects. In the presence of moderate density jump across a shear layer, in striking contrast to MHD results, MHD KH vortices are found to decay by the time one eddy turnover is completed. The decay is mediated by smaller vortices that appear within the parent vortex and stays effective even when the shear layer width is made larger. It is shown that the smaller vortices are basically of MHD nature while the seeding for these is achieved by the electron inertial effect. Application of the results to the magnetotail boundary layer is discussed

  2. Diffusion at the Earth magnetopause: enhancement by Kelvin-Helmholtz instability

    Directory of Open Access Journals (Sweden)

    R. Smets

    2007-02-01

    Full Text Available Using hybrid simulations, we examine how particles can diffuse across the Earth's magnetopause because of finite Larmor radius effects. We focus on tangential discontinuities and consider a reversal of the magnetic field that closely models the magnetopause under southward interplanetary magnetic field. When the Larmor radius is on the order of the field reversal thickness, we show that particles can cross the discontinuity. We also show that with a realistic initial shear flow, a Kelvin-Helmholtz instability develops that increases the efficiency of the crossing process. We investigate the distribution functions of the transmitted ions and demonstrate that they are structured according to a D-shape. It accordingly appears that magnetic reconnection at the magnetopause is not the only process that leads to such specific distribution functions. A simple analytical model that describes the built-up of these functions is proposed.

  3. Magnetohydrodynamic Kelvin-Helmholtz instabilities in astrophysics. 4. Single shear layer in MHD flows

    Energy Technology Data Exchange (ETDEWEB)

    Ferrari, A [Consiglio Nazionale delle Ricerche, Turin (Italy). Lab. di Cosmo-Geofisica; Turin Univ. (Italy). Ist. di Fisica Generale); Trussoni, E [Consiglio Nazionale delle Ricerche, Turin (Italy). Lab. di Cosmo-Geofisica; Max-Planck-Institut fuer Physik und Astrophysik, Garching (Germany, F.R.). Inst. fuer Extraterrestrische Physik)

    1983-11-01

    In this further paper on the physics of Kelvin-Helmholtz instabilities the case in which the fluids in relative motion are magnetized and separated by a shear layer is investigated. The present study points out, with respect to previous treatments, that different velocity profiles affect perturbations of short wavelength (as compared to the scale of the shear). Another new result is in the destabilizing effect, even in the subsonic regime, of the magnetic field on modes neutrally stable in the vortex sheet approximation. Such a behaviour is analogous to that found in the fluid case for Mach numbers >approx. = to 2. Possible astrophysical implications are also discussed.

  4. Optimal 25-Point Finite-Difference Subgridding Techniques for the 2D Helmholtz Equation

    Directory of Open Access Journals (Sweden)

    Tingting Wu

    2016-01-01

    Full Text Available We present an optimal 25-point finite-difference subgridding scheme for solving the 2D Helmholtz equation with perfectly matched layer (PML. This scheme is second order in accuracy and pointwise consistent with the equation. Subgrids are used to discretize the computational domain, including the interior domain and the PML. For the transitional node in the interior domain, the finite difference equation is formulated with ghost nodes, and its weight parameters are chosen by a refined choice strategy based on minimizing the numerical dispersion. Numerical experiments are given to illustrate that the newly proposed schemes can produce highly accurate seismic modeling results with enhanced efficiency.

  5. Cellular transfer of magnetic nanoparticles via cell microvesicles: impact on cell tracking by magnetic resonance imaging.

    Science.gov (United States)

    Silva, Amanda K Andriola; Wilhelm, Claire; Kolosnjaj-Tabi, Jelena; Luciani, Nathalie; Gazeau, Florence

    2012-05-01

    Cell labeling with magnetic nanoparticles can be used to monitor the fate of transplanted cells in vivo by magnetic resonance imaging. However, nanoparticles initially internalized in administered cells might end up in other cells of the host organism. We investigated a mechanism of intercellular cross-transfer of magnetic nanoparticles to different types of recipient cells via cell microvesicles released under cellular stress. Three cell types (mesenchymal stem cells, endothelial cells and macrophages) were labeled with 8-nm iron oxide nanoparticles. Then cells underwent starvation stress, during which they produced microvesicles that were subsequently transferred to unlabeled recipient cells. The analysis of the magnetophoretic mobility of donor cells indicated that magnetic load was partially lost under cell stress. Microvesicles shed by stressed cells participated in the release of magnetic label. Moreover, such microvesicles were uptaken by naïve cells, resulting in cellular redistribution of nanoparticles. Iron load of recipient cells allowed their detection by MRI. Cell microvesicles released under stress may be disseminated throughout the organism, where they can be uptaken by host cells. The transferred cargo may be sufficient to allow MRI detection of these secondarily labeled cells, leading to misinterpretations of the effectiveness of transplanted cells.

  6. Imaging of the internal structure of comet 67P/Churyumov-Gerasimenko from radiotomography CONSERT Data (Rosetta Mission) through a full 3D regularized inversion of the Helmholtz equations on functional spaces

    Science.gov (United States)

    Barriot, Jean-Pierre; Serafini, Jonathan; Sichoix, Lydie; Benna, Mehdi; Kofman, Wlodek; Herique, Alain

    We investigate the inverse problem of imaging the internal structure of comet 67P/ Churyumov-Gerasimenko from radiotomography CONSERT data by using a coupled regularized inversion of the Helmholtz equations. A first set of Helmholtz equations, written w.r.t a basis of 3D Hankel functions describes the wave propagation outside the comet at large distances, a second set of Helmholtz equations, written w.r.t. a basis of 3D Zernike functions describes the wave propagation throughout the comet with avariable permittivity. Both sets are connected by continuity equations over a sphere that surrounds the comet. This approach, derived from GPS water vapor tomography of the atmosphere,will permit a full 3D inversion of the internal structure of the comet, contrary to traditional approaches that use a discretization of space at a fraction of the radiowave wavelength.

  7. Ground-state magneto-optical resonances in cesium vapor confined in an extremely thin cell

    International Nuclear Information System (INIS)

    Andreeva, C.; Cartaleva, S.; Petrov, L.; Slavov, D.; Atvars, A.; Auzinsh, M.; Blush, K.

    2007-01-01

    Experimental and theoretical studies are presented related to the ground-state magneto-optical resonance observed in cesium vapor confined in an extremely thin cell (ETC), with thickness equal to the wavelength of the irradiating light. It is shown that utilization of the ETC allows one to examine the formation of a magneto-optical resonance on the individual hyperfine transitions, thus distinguishing processes resulting in dark (reduced absorption) or bright (enhanced absorption) resonance formation. We report experimental evidence of bright magneto-optical resonance sign reversal in Cs atoms confined in an ETC. A theoretical model is proposed based on the optical Bloch equations that involves the elastic interaction processes of atoms in the ETC with its walls, resulting in depolarization of the Cs excited state, which is polarized by the exciting radiation. This depolarization leads to the sign reversal of the bright resonance. Using the proposed model, the magneto-optical resonance amplitude and width as a function of laser power are calculated and compared with the experimental ones. The numerical results are in good agreement with those of experiment

  8. Localized surface plasmon resonance enhanced organic solar cell with gold nanospheres

    Energy Technology Data Exchange (ETDEWEB)

    Qiao, Linfang; Wang, Dan; Ye, Yuqian; Qian, Jun; He, Sailing [Centre for Optical and Electromagnetic Research, State Key Laboratory of Modern Optical Instrumentation, Zhejiang University, Hangzhou 310058 (China); Zuo, Lijian; Chen, Hongzheng [Department of Polymer Science and Engineering, State Key Lab of Silicon Materials, Zhejiang University, Hangzhou 310027 (China)

    2011-03-15

    We use gold nanospheres (Au NSs) to improve the performance of polymer organic solar cells. Au NSs with a diameter of about 5 nm or 15 nm were doped into the buffer layer of organic solar cells. We attribute the efficiency improvement to the size-dependent localized surface plasmon resonance (LSPR) effect of Au NSs, which can enhance the light harvest ability of active layer around the Au NSs, and increase the probability of the exciton generation and dissociation. Our results show that solar cells doped with 15 nm-diameter Au NSs exhibit significant improvement of the efficiency (from 1.99% to 2.36%), while solar cells doped with only 5 nm-diameter Au NSs did not give obvious improvement of the performance. (author)

  9. Magnetohydrodynamic Kelvin-Helmholtz instabilities in astrophysics. 1. Relativistic flows-plane boundary layer in vortex sheet approximation

    Energy Technology Data Exchange (ETDEWEB)

    Ferrari, A; Trussoni, E; Zaninetti, L [Consiglio Nazionale delle Ricerche, Turin (Italy). Lab. di Cosmo-Geofisica; Turin Univ. (Italy). Ist. di Fisica)

    1980-11-01

    In this paper some unsolved problems of the linear MHD Kelvin-Helmholtz instability are re-examined, starting from the analysis of relativistic (and non-relativistic) flows in the approximation of a plane vortex sheet, for the contact layer between the fluids in relative motion. Results are discussed for a range of physical parameters in specific connection with application to models of jets in extragalactic radio sources. Other physical aspects of the instability will be considered in forthcoming papers.

  10. Benchmark calculations on resonance absorption by 238U in a PWR pin-cell geometry

    International Nuclear Information System (INIS)

    Kruijf, W.J.M. de; Janssen, A.J.

    1993-12-01

    Very accurate Monte Carlo calculations with MCNP have been performed to serve as a reference for benchmark calculations on resonance absorption by 238 U in a typical PWR pin-cell geometry. Calculations with the energy-pointwise slowing down code ROLAIDS-CPM show that this code calculates the resonance absorption accurately. Calculations with the multigroup discrete ordinates code XSDRN show that accurate results can only be achieved with a very fine energy mesh. (orig.)

  11. On Multiple Hall-Like Electron Currents and Tripolar Guide Magnetic Field Perturbations During Kelvin-Helmholtz Waves

    Science.gov (United States)

    Sturner, Andrew P.; Eriksson, Stefan; Nakamura, Takuma; Gershman, Daniel J.; Plaschke, Ferdinand; Ergun, Robert E.; Wilder, Frederick D.; Giles, Barbara; Pollock, Craig; Paterson, William R.; Strangeway, Robert J.; Baumjohann, Wolfgang; Burch, James L.

    2018-02-01

    Two magnetopause current sheet crossings with tripolar guide magnetic field signatures were observed by multiple Magnetosphere Multiscale (MMS) spacecraft during Kelvin-Helmholtz wave activity. The two out-of-plane magnetic field depressions of the tripolar guide magnetic field are largely supported by the observed in-plane electron currents, which are reminiscent of two clockwise Hall current loop systems. A comparison with a three-dimensional kinetic simulation of Kelvin-Helmholtz waves and vortex-induced reconnection suggests that MMS likely encountered the two Hall magnetic field depressions on either side of a magnetic reconnection X-line. Moreover, MMS observed an out-of-plane current reversal and a corresponding in-plane magnetic field rotation at the center of one of the current sheets, suggesting the presence of two adjacent flux ropes. The region inside one of the ion-scale flux ropes was characterized by an observed decrease of the total magnetic field, a strong axial current, and significant enhancements of electron density and parallel electron temperature. The flux rope boundary was characterized by currents opposite this axial current, strong in-plane and converging electric fields, parallel electric fields, and weak electron-frame Joule dissipation. These return current region observations may reflect a need to support the axial current rather than representing local reconnection signatures in the absence of any exhausts.

  12. Inverse random source scattering for the Helmholtz equation in inhomogeneous media

    Science.gov (United States)

    Li, Ming; Chen, Chuchu; Li, Peijun

    2018-01-01

    This paper is concerned with an inverse random source scattering problem in an inhomogeneous background medium. The wave propagation is modeled by the stochastic Helmholtz equation with the source driven by additive white noise. The goal is to reconstruct the statistical properties of the random source such as the mean and variance from the boundary measurement of the radiated random wave field at multiple frequencies. Both the direct and inverse problems are considered. We show that the direct problem has a unique mild solution by a constructive proof. For the inverse problem, we derive Fredholm integral equations, which connect the boundary measurement of the radiated wave field with the unknown source function. A regularized block Kaczmarz method is developed to solve the ill-posed integral equations. Numerical experiments are included to demonstrate the effectiveness of the proposed method.

  13. Numerical solution of the helmholtz equation for the superellipsoid via the galerkin method

    Directory of Open Access Journals (Sweden)

    Hy Dinh

    2013-01-01

    Full Text Available The objective of this work was to find the numerical solution of the Dirichlet problem for the Helmholtz equation for a smooth superellipsoid. The superellipsoid is a shape that is controlled by two parameters. There are some numerical issues in this type of an analysis; any integration method is affected by the wave number k, because of the oscillatory behavior of the fundamental solution. In this case we could only obtain good numerical results for super ellipsoids that were more shaped like super cones, which is a narrow range of super ellipsoids. The formula for these shapes was: $x=cos(xsin(y^{n},y=sin(xsin(y^{n},z=cos(y$ where $n$ varied from 0.5 to 4. The Helmholtz equation, which is the modified wave equation, is used in many scattering problems. This project was funded by NASA RI Space Grant for testing of the Dirichlet boundary condition for the shape of the superellipsoid. One practical value of all these computations can be getting a shape for the engine nacelles in a ray tracing the space shuttle. We are researching the feasibility of obtaining good convergence results for the superellipsoid surface. It was our view that smaller and lighter wave numbers would reduce computational costs associated with obtaining Galerkin coefficients. In addition, we hoped to significantly reduce the number of terms in the infinite series needed to modify the original integral equation, all of which were achieved in the analysis of the superellipsoid in a finite range. We used the Green's theorem to solve the integral equation for the boundary of the surface. Previously, multiple surfaces were used to test this method, such as the sphere, ellipsoid, and perturbation of the sphere, pseudosphere and the oval of Cassini Lin and Warnapala , Warnapala and Morgan .

  14. Seafloor identification in sonar imagery via simulations of Helmholtz equations and discrete optimization

    Science.gov (United States)

    Engquist, Björn; Frederick, Christina; Huynh, Quyen; Zhou, Haomin

    2017-06-01

    We present a multiscale approach for identifying features in ocean beds by solving inverse problems in high frequency seafloor acoustics. The setting is based on Sound Navigation And Ranging (SONAR) imaging used in scientific, commercial, and military applications. The forward model incorporates multiscale simulations, by coupling Helmholtz equations and geometrical optics for a wide range of spatial scales in the seafloor geometry. This allows for detailed recovery of seafloor parameters including material type. Simulated backscattered data is generated using numerical microlocal analysis techniques. In order to lower the computational cost of the large-scale simulations in the inversion process, we take advantage of a pre-computed library of representative acoustic responses from various seafloor parameterizations.

  15. MHD Kelvin-Helmholtz instability in non-hydrostatic equilibrium

    International Nuclear Information System (INIS)

    Laghouati, Y; Bouabdallah, A; Zizi, M; Alemany, A

    2007-01-01

    The present work deals with the linear stability of a magnetohydrodynamic shear flow so that a stratified inviscid fluid rotating about a vertical axis when a uniform magnetic field is applied in the direction of the streaming or zonal flow. In geophysical flow, the stability of the flow is determined by taking into account the nonhydrostatic condition depending on Richardson number R i and the deviation δ from hydrostatic equilibrium. According to Stone (Stone P H 1971 J. Fluid. Mech. 45 659), it is shown that such deviation δ decreases the growth rates of three kinds of instability which can appear as geostrophic (G), symmetric (S) and Kelvin-Helmholtz (K-H) instabilities. To be specific, the evolution of the flow is therefore considered in the light of the influence of magnetic field, particularly, on K-H instability. The results of this study are presented by the linear stability of a magnetohydrodynamic, with horizontal free-shear flow of stratified fluid, subject to rotation about the vertical axis and uniform magnetic field in the zonal direction. Results are discussed and compared to previous works as Chandrasekhar (Chandrasekhar S 1961 Hydrodynamic and hydromagnetic stability (Oxford: Clarendon Press) chapter 11 pp 481-513) and Stone

  16. Interactions between two magnetohydrodynamic Kelvin-Helmholtz instabilities

    International Nuclear Information System (INIS)

    Lai, S. H.; Ip, W.-H.

    2011-01-01

    Kelvin-Helmholtz instability (KHI) driven by velocity shear is a generator of waves found away from the vicinity of the velocity-shear layers since the fast-mode waves radiated from the surface perturbation can propagate away from the transition layer. Thus the nonlinear evolution associated with KHI is not confined near the velocity-shear layer. To understand the physical processes in multiple velocity-shear layers, the interactions between two KHIs at a pair of tangential discontinuities are studied by two-dimensional magnetohydrodynamic simulations. It is shown that the interactions between two neighboring velocity-shear layers are dominated by the propagation of the fast-mode waves radiated from KHIs in a nonuniform medium. That is, the fast-mode Mach number of the surface waves M Fy , a key factor of the nonlinear evolution of KHI, will vary with the nonuniform background plasma velocity due to the existence of two neighboring velocity-shear layers. As long as the M Fy observed in the plasma rest frame across the neighboring velocity-shear layer is larger than one, newly formed fast-mode Mach-cone-like (MCL) plane waves generated by the fast-mode waves can be found in this region. As results of the interactions of two KHIs, reflection and distortion of the MCL plane waves generate the turbulence and increase the plasma temperature, which provide possible mechanisms of heating and accelerating local plasma between two neighboring velocity-shear layers.

  17. Quantitative ferromagnetic resonance analysis of CD 133 stem cells labeled with iron oxide nanoparticles

    International Nuclear Information System (INIS)

    Gamarra, L F; Pavon, L F; Marti, L C; Moreira-Filho, C A; Amaro, E Jr; Pontuschka, W M; Mamani, J B; Costa-Filho, A J; Vieira, E D

    2008-01-01

    The aim of this work is to provide a quantitative method for analysis of the concentration of superparamagnetic iron oxide nanoparticles (SPION), determined by means of ferromagnetic resonance (FMR), with the nanoparticles coupled to a specific antibody (AC 133), and thus to express the antigenic labeling evidence for the stem cells CD 133 + . The FMR efficiency and sensitivity were proven adequate for detecting and quantifying the low amounts of iron content in the CD 133 + cells (∼6.16 x 10 5 pg in the volume of 2 μl containing 4.5 x 10 11 SPION). The quantitative method led to the result of 1.70 x 10 -13 mol of Fe (9.5 pg), or 7.0 x 10 6 nanoparticles per cell. For the quantification analysis via the FMR technique it was necessary to carry out a preliminary quantitative visualization of iron oxide-labeled cells in order to ensure that the nanoparticles coupled to the antibodies are indeed tied to the antigen at the stem cell surface and that the cellular morphology was conserved, as proof of the validity of this method. The quantitative analysis by means of FMR is necessary for determining the signal intensity for the study of molecular imaging by means of magnetic resonance imaging (MRI)

  18. Modeling and characterization of double resonant tunneling diodes for application as energy selective contacts in hot carrier solar cells

    Science.gov (United States)

    Jehl, Zacharie; Suchet, Daniel; Julian, Anatole; Bernard, Cyril; Miyashita, Naoya; Gibelli, Francois; Okada, Yoshitaka; Guillemolles, Jean-Francois

    2017-02-01

    Double resonant tunneling barriers are considered for an application as energy selective contacts in hot carrier solar cells. Experimental symmetric and asymmetric double resonant tunneling barriers are realized by molecular beam epitaxy and characterized by temperature dependent current-voltage measurements. The negative differential resistance signal is enhanced for asymmetric heterostructures, and remains unchanged between low- and room-temperatures. Within Tsu-Esaki description of the tunnel current, this observation can be explained by the voltage dependence of the tunnel transmission amplitude, which presents a resonance under finite bias for asymmetric structures. This effect is notably discussed with respect to series resistance. Different parameters related to the electronic transmission of the structure and the influence of these parameters on the current voltage characteristic are investigated, bringing insights on critical processes to optimize in double resonant tunneling barriers applied to hot carrier solar cells.

  19. A high-order particle-in-cell method for low density plasma flow and the simulation of gyrotron resonator devices

    International Nuclear Information System (INIS)

    Stock, Andreas

    2013-01-01

    Within this thesis a parallelized, transient, three-dimensional, high-order discontinuous Galerkin Particle-in-Cell solver is developed and used to simulate the resonant cavity of a gyrotron. The high-order discontinuous Galerkin approach - a Finite-Element type method - provides a fast and efficient algorithm to numerically solve Maxwell's equations used within this thesis. Besides its outstanding dissipation and dispersion properties, the discontinuous Galerkin approach easily allows for using unstructured grids, as required to simulate complex-shaped engineering devices. The discontinuous Galerkin approach approximates a wavelength with significantly less degrees of freedom compared to other methods, e.g. Finite Difference methods. Furthermore, the parallelization capabilities of the discontinuous Galerkin framework are excellent due to the very local dependencies between the elements. These properties are essential for the efficient numerical treatment of the Vlasov-Maxwell system with the Particle-in-Cell method. This system describes the self-consistent interaction of charged particles and the electromagnetic field. As central application within this thesis gyrotron resonators are simulated with the discontinuous Galerkin Particle-in-Cell method on high-performance-computers. The gyrotron is a high-power millimeter wave source, used for the electron cyclotron resonance heating of magnetically confined fusion plasma, e.g. in the Wendelstein 7-X experimental fusion-reactor. Compared to state-of-the-art simulation tools used for the design of gyrotron resonators the Particle-in-Cell method does not use any significant physically simplifications w.r.t. the modelling of the particle-field-interaction, the geometry and the wave-spectrum. Hence, it is the method of choice for validation of current simulation tools being restricted by these simplifications. So far, the Particle-in-Cell method was restricted to be used for demonstration calculations only, because

  20. A high-order particle-in-cell method for low density plasma flow and the simulation of gyrotron resonator devices

    Energy Technology Data Exchange (ETDEWEB)

    Stock, Andreas

    2013-04-26

    Within this thesis a parallelized, transient, three-dimensional, high-order discontinuous Galerkin Particle-in-Cell solver is developed and used to simulate the resonant cavity of a gyrotron. The high-order discontinuous Galerkin approach - a Finite-Element type method - provides a fast and efficient algorithm to numerically solve Maxwell's equations used within this thesis. Besides its outstanding dissipation and dispersion properties, the discontinuous Galerkin approach easily allows for using unstructured grids, as required to simulate complex-shaped engineering devices. The discontinuous Galerkin approach approximates a wavelength with significantly less degrees of freedom compared to other methods, e.g. Finite Difference methods. Furthermore, the parallelization capabilities of the discontinuous Galerkin framework are excellent due to the very local dependencies between the elements. These properties are essential for the efficient numerical treatment of the Vlasov-Maxwell system with the Particle-in-Cell method. This system describes the self-consistent interaction of charged particles and the electromagnetic field. As central application within this thesis gyrotron resonators are simulated with the discontinuous Galerkin Particle-in-Cell method on high-performance-computers. The gyrotron is a high-power millimeter wave source, used for the electron cyclotron resonance heating of magnetically confined fusion plasma, e.g. in the Wendelstein 7-X experimental fusion-reactor. Compared to state-of-the-art simulation tools used for the design of gyrotron resonators the Particle-in-Cell method does not use any significant physically simplifications w.r.t. the modelling of the particle-field-interaction, the geometry and the wave-spectrum. Hence, it is the method of choice for validation of current simulation tools being restricted by these simplifications. So far, the Particle-in-Cell method was restricted to be used for demonstration calculations only, because

  1. Off-resonance plasmonic enhanced femtosecond laser optoporation and transfection of cancer cells.

    Science.gov (United States)

    Baumgart, Judith; Humbert, Laure; Boulais, Étienne; Lachaine, Rémi; Lebrun, Jean-Jaques; Meunier, Michel

    2012-03-01

    A femtosecond laser based transfection method using off-resonance plasmonic gold nanoparticles is described. For human cancer melanoma cells, the treatment leads to a very high perforation rate of 70%, transfection efficiency three times higher than for conventional lipofection, and very low toxicity (transfection for skin cancer treatment. Copyright © 2011 Elsevier Ltd. All rights reserved.

  2. Cancer cell imaging by stable wet near-field scanning optical microscope with resonance tracking method

    International Nuclear Information System (INIS)

    Park, Kyoung-Duck; Park, Doo-Jae; Jeong, Mun-Seok; Choi, Geun-Chang; Lee, Seung-Gol; Byeon, Clare-Chisu; Choi, Soo-Bong

    2014-01-01

    We report on a successful topographical and optical imaging of various cancer cells in liquid and in air by using a stable wet near-field scanning optical microscope that utilizes a resonance tracking method. We observed a clear dehydration which gives rise to a decrease in the cell volume down to 51%. In addition, a micro-ball lens effect due to the round-shaped young cancer cells was observed from near-field imaging, where the refractive index of young cancer cells was deduced.

  3. Cancer cell imaging by stable wet near-field scanning optical microscope with resonance tracking method

    Energy Technology Data Exchange (ETDEWEB)

    Park, Kyoung-Duck [Sungkyunkwan University, Suwon (Korea, Republic of); Inha University, Incheon (Korea, Republic of); Park, Doo-Jae; Jeong, Mun-Seok [Sungkyunkwan University, Suwon (Korea, Republic of); Choi, Geun-Chang [Seoul National University, Seoul (Korea, Republic of); Lee, Seung-Gol [Inha University, Incheon (Korea, Republic of); Byeon, Clare-Chisu [Kyungpook National University, Daegu (Korea, Republic of); Choi, Soo-Bong [Incheon National University, Incheon (Korea, Republic of)

    2014-05-15

    We report on a successful topographical and optical imaging of various cancer cells in liquid and in air by using a stable wet near-field scanning optical microscope that utilizes a resonance tracking method. We observed a clear dehydration which gives rise to a decrease in the cell volume down to 51%. In addition, a micro-ball lens effect due to the round-shaped young cancer cells was observed from near-field imaging, where the refractive index of young cancer cells was deduced.

  4. High Contrast Coherent Population Trapping Resonances in Cs Vapour Cells with a Simple-Architecture Laser System

    International Nuclear Information System (INIS)

    Liu, Xiaochi

    2013-01-01

    This thesis reports the development of a simple-architecture laser system resonant at 895 nm used for the detection of high-contrast coherent population trapping (CPT) resonances in Cs vapor cells. The laser system combines a distributed feedback-diode (DFB) laser, a pigtailed Mach-Zehnder intensity electro-optic modulator (EOM) driven at 4.596 GHz for the generation of optical sidebands frequency-split by 9.192 GHz and a Michelson delay-line system to produce a bi-chromatic optical field that alternates between right and left circular polarization. This polarization pumping scheme, first proposed by Happer's group in Princeton on K atoms, allows to optically pump a maximum number of Cs atoms into the 0-0 magnetic field insensitive clock transition. Advanced noise reduction techniques were implemented in order to stabilize the laser power, the optical carrier suppression at the output of the EOM and the DFB laser frequency. Using this system, we demonstrated the detection of CPT resonances with a contrast of 80% in cm-scale Cs vapor cells. This contrast was measured to be increased until a saturation effect with the laser power at the expense of the CPT line broadening. To circumvent this issue, we proposed with a simple setup Ramsey spectroscopy of CPT resonances in vapor cells to combine high-contrast and narrow line width of the CPT resonances. In this setup, the EOM is used both for optical sidebands generation and light switch to produce Ramsey interaction. Ramsey fringes of 166 Hz line width with a contrast better than 30% were detected with this setup. This laser system will be in a near future devoted to be used for the development of a high-performance CPT-based atomic clock. (author)

  5. In vivo tracking of neuronal-like cells by magnetic resonance in rabbit models of spinal cord injury

    Science.gov (United States)

    Zhang, Ruiping; Zhang, Kun; Li, Jianding; Liu, Qiang; Xie, Jun

    2013-01-01

    In vitro experiments have demonstrated that neuronal-like cells derived from bone marrow mesenchymal stem cells can survive, migrate, integrate and help to restore the function and behaviors of spinal cord injury models, and that they may serve as a suitable approach to treating spinal cord injury. However, it is very difficult to track transplanted cells in vivo. In this study, we injected superparamagnetic iron oxide-labeled neuronal-like cells into the subarachnoid space in a rabbit model of spinal cord injury. At 7 days after cell transplantation, a small number of dot-shaped low signal intensity shadows were observed in the spinal cord injury region, and at 14 days, the number of these shadows increased on T2-weighted imaging. Perl's Prussian blue staining detected dot-shaped low signal intensity shadows in the spinal cord injury region, indicative of superparamagnetic iron oxide nanoparticle-labeled cells. These findings suggest that transplanted neuronal-like cells derived from bone marrow mesenchymal stem cells can migrate to the spinal cord injury region and can be tracked by magnetic resonance in vivo. Magnetic resonance imaging represents an efficient noninvasive technique for visually tracking transplanted cells in vivo. PMID:25206659

  6. Mean shear flows, zonal flows, and generalized Kelvin-Helmholtz modes in drift wave turbulence: A minimal model for L→H transition

    International Nuclear Information System (INIS)

    Kim, Eun-jin; Diamond, P.H.

    2003-01-01

    The dynamics of and an interplay among structures (mean shear flows, zonal flows, and generalized Kelvin-Helmholtz modes) are studied in drift wave turbulence. Mean shear flows are found to inhibit the nonlinear generation of zonal flows by weakening the coherent modulation response of the drift wave spectrum. Based on this result, a minimal model for the L→H (low- to high-confinement) transition is proposed, which involves the amplitude of drift waves, zonal flows, and the density gradient. A transition to quiescent H-mode sets in as the profile becomes sufficiently steep to completely damp out drift waves, following an oscillatory transition phase where zonal flows regulate drift wave turbulence. The different roles of mean flows and zonal flows are elucidated. Finally, the effect of poloidally nonaxisymmetric structures (generalized Kelvin-Helmholtz mode) on anomalous transport is investigated, especially in reference to damping of collisionless zonal flows. Results indicate that nonlinear excitation of this structure can be potentially important in enhancing anomalous transport as well as in damping zonal flows

  7. Quantitative ferromagnetic resonance analysis of CD 133 stem cells labeled with iron oxide nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Gamarra, L F; Pavon, L F; Marti, L C; Moreira-Filho, C A; Amaro, E Jr [Instituto Israelita de Ensino e Pesquisa Albert Einstein, IIEPAE, Sao Paulo 05651-901 (Brazil); Pontuschka, W M; Mamani, J B [Instituto de Fisica, Universidade de Sao Paulo, Sao Paulo 05315-970 (Brazil); Costa-Filho, A J; Vieira, E D [Instituto de Fisica de Sao Carlos, Universidade de Sao Paulo, Sao Carlos 13560-970 (Brazil)], E-mail: lgamarra@einstein.br

    2008-05-21

    The aim of this work is to provide a quantitative method for analysis of the concentration of superparamagnetic iron oxide nanoparticles (SPION), determined by means of ferromagnetic resonance (FMR), with the nanoparticles coupled to a specific antibody (AC 133), and thus to express the antigenic labeling evidence for the stem cells CD 133{sup +}. The FMR efficiency and sensitivity were proven adequate for detecting and quantifying the low amounts of iron content in the CD 133{sup +} cells ({approx}6.16 x 10{sup 5} pg in the volume of 2 {mu}l containing 4.5 x 10{sup 11} SPION). The quantitative method led to the result of 1.70 x 10{sup -13} mol of Fe (9.5 pg), or 7.0 x 10{sup 6} nanoparticles per cell. For the quantification analysis via the FMR technique it was necessary to carry out a preliminary quantitative visualization of iron oxide-labeled cells in order to ensure that the nanoparticles coupled to the antibodies are indeed tied to the antigen at the stem cell surface and that the cellular morphology was conserved, as proof of the validity of this method. The quantitative analysis by means of FMR is necessary for determining the signal intensity for the study of molecular imaging by means of magnetic resonance imaging (MRI)

  8. High-quality electromagnetically-induced absorption resonances in a buffer-gas-filled vapour cell

    Science.gov (United States)

    Brazhnikov, D. V.; Ignatovich, S. M.; Vishnyakov, V. I.; Skvortsov, M. N.; Andreeva, Ch; Entin, V. M.; Ryabtsev, I. I.

    2018-02-01

    Magneto-optical subnatural-linewidth resonances of electromagnetically-induced absorption (EIA) in an alkali vapour cell have been experimentally studied. The observation configuration includes using two counter-propagating pumps and probe light waves with mutually orthogonal linear polarizations, exciting an open optical transition in the 87Rb D 1 line in the presence of argon buffer gas. The EIA signals registered in a probe-wave transmission reach an unprecedented contrast of about 135% with respect to the wide ‘Doppler’ absorption pedestal and 29% with respect to the level of background transmission signal. These contrast values correspond to a relatively small resonance full width at half maximum of about 7.2 mG (5.2 kHz). The width of the narrowest EIA resonance observed is about 2.1 mG (1.5 kHz). To our knowledge, such a large relative contrast at the kHz-width is the record result for EIA resonances. In general, the work has experimentally proved that the magneto-optical scheme used has very good prospects for various quantum technologies (quantum sensors of weak magnetic fields, optical switches and other photonic elements).

  9. Blob Formation and Ejection in Coronal Jets due to the Plasmoid and Kelvin–Helmholtz Instabilities

    Energy Technology Data Exchange (ETDEWEB)

    Ni, Lei; Lin, Jun [Yunnan Observatories, Chinese Academy of Sciences, 396 Yangfangwang, Guandu District, Kunming, 650216 (China); Zhang, Qing-Min [Key Laboratory for Dark Matter and Space Science, Purple Mountain Observatory, Chinese Academy of Sciences, Nanjing 210008 (China); Murphy, Nicholas A., E-mail: leini@ynao.ac.cn [Harvard-Smithsonian Center for Astrophysics, Cambridge, MA 02138 (United States)

    2017-05-20

    We perform 2D resistive magnetohydrodynamic simulations of coronal jets driven by flux emergence along the lower boundary. The reconnection layers are susceptible to the formation of blobs that are ejected in the jet. Our simulation with low plasma β (Case I) shows that magnetic islands form easily and propagate upward in the jet. These islands are multithermal and thus are predicted to show up in hot channels (335 Å and 211 Å) and the cool channel (304 Å) in observations by the Atmospheric Imaging Assembly (AIA) on the Solar Dynamics Observatory . The islands have maximum temperatures of 8 MK, lifetimes of 120 s, diameters of 6 Mm, and velocities of 200 km s{sup −1}. These parameters are similar to the properties of blobs observed in extreme-ultraviolet (EUV) jets by AIA. The Kelvin–Helmholtz instability develops in our simulation with moderately high plasma β (Case II) and leads to the formation of bright vortex-like blobs above the multiple high magnetosonic Mach number regions that appear along the jet. These vortex-like blobs can also be identified in the AIA channels. However, they eventually move downward and disappear after the high magnetosonic Mach number regions disappear. In the lower plasma β case, the lifetime for the jet is shorter, the jet and magnetic islands are formed with higher velocities and temperatures, the current-sheet fragments are more chaotic, and more magnetic islands are generated. Our results show that the plasmoid instability and Kelvin–Helmholtz instability along the jet are both possible causes of the formation of blobs observed at EUV wavelengths.

  10. A Cell-to-Cell Battery Equalizer With Zero-Current Switching and Zero-Voltage Gap Based on Quasi-Resonant LC Converter and Boost Converter

    DEFF Research Database (Denmark)

    Shang, Yunlong; Zhang, Chenghui; Cui, Naxin

    2015-01-01

    these difficulties, an innovative direct cell-to-cell battery equalizer based on quasi-resonant LC converter (QRLCC) and boost DC-DC converter (BDDC) is proposed. The QRLCC is employed to gain zero-current switching (ZCS), leading to a reduction of power losses. The BDDC is employed to enhance the equalization...

  11. Intrinsic periodic and aperiodic stochastic resonance in an electrochemical cell

    Science.gov (United States)

    Tiwari, Ishant; Phogat, Richa; Parmananda, P.; Ocampo-Espindola, J. L.; Rivera, M.

    2016-08-01

    In this paper we show the interaction of a composite of a periodic or aperiodic signal and intrinsic electrochemical noise with the nonlinear dynamics of an electrochemical cell configured to study the corrosion of iron in an acidic media. The anodic voltage setpoint (V0) in the cell is chosen such that the anodic current (I ) exhibits excitable fixed point behavior in the absence of noise. The subthreshold periodic (aperiodic) signal consists of a train of rectangular pulses with a fixed amplitude and width, separated by regular (irregular) time intervals. The irregular time intervals chosen are of deterministic and stochastic origins. The amplitude of the intrinsic internal noise, regulated by the concentration of chloride ions, is then monotonically increased, and the provoked dynamics are analyzed. The signal to noise ratio and the cross-correlation coefficient versus the chloride ions' concentration curves have a unimodal shape indicating the emergence of an intrinsic periodic or aperiodic stochastic resonance. The abscissa for the maxima of these unimodal curves correspond to the optimum value of intrinsic noise where maximum regularity of the invoked dynamics is observed. In the particular case of the intrinsic periodic stochastic resonance, the scanning electron microscope images for the electrode metal surfaces are shown for certain values of chloride ions' concentrations. These images, qualitatively, corroborate the emergence of order as a result of the interaction between the nonlinear dynamics and the composite signal.

  12. Functional magnetic resonance microscopy at single-cell resolution in Aplysia californica

    Science.gov (United States)

    Radecki, Guillaume; Nargeot, Romuald; Jelescu, Ileana Ozana; Le Bihan, Denis; Ciobanu, Luisa

    2014-01-01

    In this work, we show the feasibility of performing functional MRI studies with single-cell resolution. At ultrahigh magnetic field, manganese-enhanced magnetic resonance microscopy allows the identification of most motor neurons in the buccal network of Aplysia at low, nontoxic Mn2+ concentrations. We establish that Mn2+ accumulates intracellularly on injection into the living Aplysia and that its concentration increases when the animals are presented with a sensory stimulus. We also show that we can distinguish between neuronal activities elicited by different types of stimuli. This method opens up a new avenue into probing the functional organization and plasticity of neuronal networks involved in goal-directed behaviors with single-cell resolution. PMID:24872449

  13. Calculation of the fine spectrum and integration of the resonance cross sections in the cells

    International Nuclear Information System (INIS)

    Paratte, J.M.

    1986-10-01

    The code BOXER is used for the neutronics calculations of two-dimensional LWR arrays. During the calculation of the group constants of the cells (pin, clad and moderator), the program SLOFIN, a BOXER module, allows taking into account the self-shielding of the resonances. The resonance range is devided into two parts: - above 907 eV the cross sections are condensed into groups by the library code ETOBOX. In SLOFIN, these values are interpolated over the equivalent cross section and the temperature. The interpolation formula chosen gives an accuracy better than 1% for values of the equivalent cross section larger than 5 barns. - between 4 and 907 eV, the cross sections are given in pointwise form as a function of the lethargy. At first a list of pointwise macroscopic cross section is established. Then the fine spectrum in the cell is calculated in 2 or 3 zones by means of the collision probability theory. In the central zone one resonant pseudo-nuclide is considered for the calculation of the scattering source, while the light nuclides are explicitly treated but under the assumption of energy independent cross sections. The fine spectrum is then used as a weihting function for the condensation of the pointwise cross sections of the resonant nuclides into energy groups. The procedure was checked on the basis of the TRX-1 to -4 and BAPL-UO 2 -1 to -3 experiments which are used as benchmarks for the tests of the ENDF/B libraries. The comparisons with other calculation results show that the deviations observed are typical for the basic cross sections. The method proposed shows a good accuracy in the application range foreseen for BOXER. It is also fast enough to be used as a standard method in a cell code. (author)

  14. Reconstruction of propagating Kelvin-Helmholtz vortices at Mercury's magnetopause

    Science.gov (United States)

    Sundberg, Torbjörn; Boardsen, Scott A.; Slavin, James A.; Blomberg, Lars G.; Cumnock, Judy A.; Solomon, Sean C.; Anderson, Brian J.; Korth, Haje

    2011-12-01

    A series of quasi-periodic magnetopause crossings were recorded by the MESSENGER spacecraft during its third flyby of Mercury on 29 September 2009, likely caused by a train of propagating Kelvin-Helmholtz (KH) vortices. We here revisit the observations to study the internal structure of the waves. Exploiting MESSENGER's rapid traversal of the magnetopause, we show that the observations permit a reconstruction of the structure of a rolled-up KH vortex directly from the spacecraft's magnetic field measurements. The derived geometry is consistent with all large-scale fluctuations in the magnetic field data, establishes the non-linear nature of the waves, and shows their vortex-like structure. In several of the wave passages, a reduction in magnetic field strength is observed in the middle of the wave, which is characteristic of rolled-up vortices and is related to the increase in magnetic pressure required to balance the centrifugal force on the plasma in the outer regions of a vortex, previously reported in computer simulations. As the KH wave starts to roll up, the reconstructed geometry suggests that the vortices develop two gradual transition regions in the magnetic field, possibly related to the mixing of magnetosheath and magnetospheric plasma, situated at the leading edges from the perspectives of both the magnetosphere and the magnetosheath.

  15. An efficient Helmholtz solver for acoustic transversely isotropic media

    KAUST Repository

    Wu, Zedong

    2017-11-11

    The acoustic approximation, even for anisotropic media, is widely used in current industry imaging and inversion algorithms mainly because P-waves constitute the majority of the energy recorded in seismic exploration. The resulting acoustic formulas tend to be simpler, resulting in more efficient implementations, and depend on less medium parameters. However, conventional solutions of the acoustic wave equation with higher-order derivatives suffer from S-wave artifacts. Thus, we propose to separate the quasi-P wave propagation in anisotropic media into the elliptic anisotropic operator (free of the artifacts) and the non-elliptic-anisotropic components, which form a pseudo-differential operator. We, then, develop a separable approximation of the dispersion relation of non-elliptic-anisotropic components, specifically for transversely isotropic (TI) media. Finally, we iteratively solve the simpler lower-order elliptical wave equation for a modified source function that includes the non-elliptical terms represented in the Fourier domain. A frequency domain Helmholtz formulation of the approach renders the iterative implementation efficient as the cost is dominated by the Lower-Upper (LU) decomposition of the impedance matrix for the simpler elliptical anisotropic model. Also, the resulting wavefield is free of S-wave artifacts and has balanced amplitude. Numerical examples show that the method is reasonably accurate and efficient.

  16. Kelvin-Helmholtz evolution in subsonic cold streams feeding galaxies

    Science.gov (United States)

    Angulo, Adrianna; Coffing, S.; Kuranz, C.; Drake, R. P.; Klein, S.; Trantham, M.; Malamud, G.

    2017-10-01

    The most prolific star formers in cosmological history lie in a regime where dense filament structures carried substantial mass into the galaxy to sustain star formation without producing a shock. However, hydrodynamic instabilities present on the filament surface limit the ability of such structures to deliver dense matter deeply enough to sustain star formation. Simulations lack the finite resolution necessary to allow fair treatment of the instabilities present at the stream boundary. Using the Omega EP laser, we simulate this mode of galaxy formation with a cold, dense, filament structure within a hotter, subsonic flow and observe the interface evolution. Machined surface perturbations stimulate the development of the Kelvin-Helmholtz (KH) instability due to the resultant shear between the two media. A spherical crystal imaging system produces high-resolution radiographs of the KH structures along the filament surface. The results from the first experiments of this kind, using a rod with single-mode, long-wavelength modulations, will be discussed. This work is funded by the U.S. Department of Energy, through the NNSA-DS and SC-OFES Joint Program in High-Energy-Density Laboratory Plasmas, Grant Number DE-NA0002956, and the National Laser User Facility Program, Grant Number DE-NA0002719, and through.

  17. An efficient Helmholtz solver for acoustic transversely isotropic media

    KAUST Repository

    Wu, Zedong; Alkhalifah, Tariq Ali

    2017-01-01

    The acoustic approximation, even for anisotropic media, is widely used in current industry imaging and inversion algorithms mainly because P-waves constitute the majority of the energy recorded in seismic exploration. The resulting acoustic formulas tend to be simpler, resulting in more efficient implementations, and depend on less medium parameters. However, conventional solutions of the acoustic wave equation with higher-order derivatives suffer from S-wave artifacts. Thus, we propose to separate the quasi-P wave propagation in anisotropic media into the elliptic anisotropic operator (free of the artifacts) and the non-elliptic-anisotropic components, which form a pseudo-differential operator. We, then, develop a separable approximation of the dispersion relation of non-elliptic-anisotropic components, specifically for transversely isotropic (TI) media. Finally, we iteratively solve the simpler lower-order elliptical wave equation for a modified source function that includes the non-elliptical terms represented in the Fourier domain. A frequency domain Helmholtz formulation of the approach renders the iterative implementation efficient as the cost is dominated by the Lower-Upper (LU) decomposition of the impedance matrix for the simpler elliptical anisotropic model. Also, the resulting wavefield is free of S-wave artifacts and has balanced amplitude. Numerical examples show that the method is reasonably accurate and efficient.

  18. First-order system least-squares for the Helmholtz equation

    Energy Technology Data Exchange (ETDEWEB)

    Lee, B.; Manteuffel, T.; McCormick, S.; Ruge, J.

    1996-12-31

    We apply the FOSLS methodology to the exterior Helmholtz equation {Delta}p + k{sup 2}p = 0. Several least-squares functionals, some of which include both H{sup -1}({Omega}) and L{sup 2}({Omega}) terms, are examined. We show that in a special subspace of [H(div; {Omega}) {intersection} H(curl; {Omega})] x H{sup 1}({Omega}), each of these functionals are equivalent independent of k to a scaled H{sup 1}({Omega}) norm of p and u = {del}p. This special subspace does not include the oscillatory near-nullspace components ce{sup ik}({sup {alpha}x+{beta}y)}, where c is a complex vector and where {alpha}{sub 2} + {beta}{sup 2} = 1. These components are eliminated by applying a non-standard coarsening scheme. We achieve this scheme by introducing {open_quotes}ray{close_quotes} basis functions which depend on the parameter pair ({alpha}, {beta}), and which approximate ce{sup ik}({sup {alpha}x+{beta}y)} well on the coarser levels where bilinears cannot. We use several pairs of these parameters on each of these coarser levels so that several coarse grid problems are spun off from the finer levels. Some extensions of this theory to the transverse electric wave solution for Maxwell`s equations will also be presented.

  19. Guided-mode resonant solar cells and flat-top reflectors: Analysis, design, fabrication and characterization

    Science.gov (United States)

    Khaleque, Tanzina

    This dissertation addresses the guided-mode resonance (GMR) effect and its applications. In particular, this study presents theoretical analysis and corresponding experiments on two important GMR devices that can be broadly described as GMR-enabled thin-film solar cells and flat-top reflectors. The GMR-induced enhanced absorption of input light is observed and quantified in a fabricated nano-patterned amorphous silicon (a-Si) thin-film. Compared to a reference homogeneous thin-film of a-Si, approximately 50% integrated absorbance enhancement is achieved in the patterned structure. This result motivates the application of these resonance effects in thin-film solar cells where enhanced solar absorbance is a crucial requirement. Light trapping in thin-film solar cells through the GMR effect is theoretically explained and experimentally demonstrated. Nano-patterned solar cells with 300-nm periods in one-dimensional gratings are designed, fabricated, and characterized. Compared to a planar reference solar cell, around 35% integrated absorption enhancement is observed over the 450--750-nm wavelength range. This light-management method results in enhanced short-circuit current density of 14.8 mA/cm 2, which is a ˜40% improvement over planar solar cells. The experimental demonstration proves the potential of simple and well-designed guided-mode resonant features in thin-film solar cells. In order to complement the research on GMR thin-film solar cells, a single-step, low-cost fabrication method for generating resonant nano-grating patterns on poly-methyl-methacrylate (PMMA; plexiglas) substrates using thermal nano-imprint lithography is reported. The imprinted structures of both one and two dimensional nano-grating patterns with 300 nm period are fabricated. Thin films of indium-tin-oxide and silicon are deposited over patterned substrates and the absorbance of the films is measured. Around 25% and 45% integrated optical absorbance enhancement is observed over the 450-nm

  20. Buffer-gas-induced absorption resonances in Rb vapor

    International Nuclear Information System (INIS)

    Mikhailov, Eugeniy E.; Novikova, Irina; Rostovtsev, Yuri V.; Welch, George R.

    2004-01-01

    We observe transformation of the electromagnetically induced transparency (EIT) resonance into an absorption resonance in a Λ interaction configuration in a cell filled with 87 Rb and a buffer gas. This transformation occurs as one-photon detuning of the coupling fields is varied from the atomic transition. No such absorption resonance is found in the absence of a buffer gas. The width of the absorption resonance is several times smaller than the width of the EIT resonance, and the changes of absorption near these resonances are about the same. Similar absorption resonances are detected in the Hanle configuration in a buffered cell

  1. Metglas-Elgiloy bi-layer, stent cell resonators for wireless monitoring of viscosity and mass loading

    KAUST Repository

    Viswanath, Anupam; Green, Scott Ryan; Kosel, Jü rgen; Gianchandani, Yogesh B.

    2012-01-01

    This paper presents the design and evaluation of magnetoelastic sensors intended for wireless monitoring of tissue accumulation in peripheral artery stents. The sensors are fabricated from 28 μm thick foils of magnetoelastic 2826MB Metglas™, an amorphous Ni-Fe alloy. The sensor layer consists of a frame and an active resonator portion. The frame consists of 150 μm wide struts that are patterned in the same wishbone array pattern as a 12 mm × 1.46 mm Elgiloy stent cell. The active portion is a 10 mm long symmetric leaf shape and is anchored to the frame at mid length. The active portion nests within the stent cell, with a uniform gap separating the two. A gold-indium eutectic bonding process is used to bond Metglas™ and Elgiloy foils, which are subsequently patterned to form bi-layer resonators. The response of the sensor to viscosity changes and mass loading that precede and accompany artery occlusion is tested in vitro. The typical sensitivity to viscosity of the fundamental, longitudinal resonant frequency at 361 kHz is 427 ppm cP -1 over a 1.1-8.6 cP range. The sensitivity to mass loading is typically between 63000 and 65000 ppm mg-1 with the resonant frequency showing a reduction of 8.1% for an applied mass that is 15% of the unloaded mass of the sensor. This is in good agreement with the theoretical response. © 2013 IOP Publishing Ltd.

  2. Metglas-Elgiloy bi-layer, stent cell resonators for wireless monitoring of viscosity and mass loading

    KAUST Repository

    Viswanath, Anupam

    2012-12-21

    This paper presents the design and evaluation of magnetoelastic sensors intended for wireless monitoring of tissue accumulation in peripheral artery stents. The sensors are fabricated from 28 μm thick foils of magnetoelastic 2826MB Metglas™, an amorphous Ni-Fe alloy. The sensor layer consists of a frame and an active resonator portion. The frame consists of 150 μm wide struts that are patterned in the same wishbone array pattern as a 12 mm × 1.46 mm Elgiloy stent cell. The active portion is a 10 mm long symmetric leaf shape and is anchored to the frame at mid length. The active portion nests within the stent cell, with a uniform gap separating the two. A gold-indium eutectic bonding process is used to bond Metglas™ and Elgiloy foils, which are subsequently patterned to form bi-layer resonators. The response of the sensor to viscosity changes and mass loading that precede and accompany artery occlusion is tested in vitro. The typical sensitivity to viscosity of the fundamental, longitudinal resonant frequency at 361 kHz is 427 ppm cP -1 over a 1.1-8.6 cP range. The sensitivity to mass loading is typically between 63000 and 65000 ppm mg-1 with the resonant frequency showing a reduction of 8.1% for an applied mass that is 15% of the unloaded mass of the sensor. This is in good agreement with the theoretical response. © 2013 IOP Publishing Ltd.

  3. Resonant nano-antennas for light trapping in plasmonic solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Mokkapati, S; Beck, F J; Catchpole, K R [Centre for Sustainable Energy Systems, College of Engineering and Computer Science, Australian National University, Canberra, 0200 (Australia); De Waele, R; Polman, A, E-mail: sudha.mokkapati@anu.edu.au [Center for Nanophotonics, FOM Institute AMOLF, Science Park 104, 1098 XG Amsterdam (Netherlands)

    2011-05-11

    We investigate the influence of nanoparticle height on light trapping in thin-film solar cells covered with metal nanoparticles. We show that in taller nanoparticles the scattering cross-section is enhanced by resonant excitation of plasmonic standing waves. Tall nanoparticles have higher coupling efficiency when placed on the illuminated surface of the cell than on the rear of the cell due to their forward scattering nature. One of the major factors affecting the coupling efficiency of these particles is the phase shift of surface plasmon polaritons propagating along the nanoparticle due to reflection from the Ag/Si or Ag/air interface. The high scattering cross-sections of tall nanoparticles on the illuminated surface of the cell could be exploited for efficient light trapping by modifying the coupling efficiency of nanoparticles by engineering this phase shift. We demonstrate that the path length enhancement (with a nanoparticle of height 500 nm) at an incident wavelength of 700 nm can be increased from {approx}6 to {approx}16 by modifying the phase shift at the Ag/air interface by coating the surface of the nanoparticle with a layer of Si.

  4. Fluorescence resonance energy transfer imaging of CFP/YFP labeled NDH in cyanobacterium cell

    International Nuclear Information System (INIS)

    Ji Dongmei; Lv Wei; Huang Zhengxi; Xia Andong; Xu Min; Ma Weimin; Mi Hualing; Ogawa Teruo

    2007-01-01

    The laser confocal scanning microscopy combined with time-correlated single photon counting imaging technique to obtain fluorescence intensity and fluorescence lifetime images for fluorescence resonance energy transfer measurement is reported. Both the fluorescence lifetime imaging microscopy (FLIM) and intensity images show inhomogeneous cyan fluorescent protein and yellow fluorescent protein (CFP /YFP) expression or inhomogeneous energy transfer between CFP and YFP over whole cell. The results presented in this work show that FLIM could be a potential method to reveal the structure-function behavior of NAD(P)H dehydrogenase complexes in living cell

  5. Using magnetic resonance imaging to evaluate dendritic cell-based vaccination.

    Directory of Open Access Journals (Sweden)

    Peter M Ferguson

    Full Text Available Cancer immunotherapy with antigen-loaded dendritic cell-based vaccines can induce clinical responses in some patients, but further optimization is required to unlock the full potential of this strategy in the clinic. Optimization is dependent on being able to monitor the cellular events that take place once the dendritic cells have been injected in vivo, and to establish whether antigen-specific immune responses to the tumour have been induced. Here we describe the use of magnetic resonance imaging (MRI as a simple, non-invasive approach to evaluate vaccine success. By loading the dendritic cells with highly magnetic iron nanoparticles it is possible to assess whether the injected cells drain to the lymph nodes. It is also possible to establish whether an antigen-specific response is initiated by assessing migration of successive rounds of antigen-loaded dendritic cells; in the face of a successfully primed cytotoxic response, the bulk of antigen-loaded cells are eradicated on-route to the node, whereas cells without antigen can reach the node unchecked. It is also possible to verify the induction of a vaccine-induced response by simply monitoring increases in draining lymph node size as a consequence of vaccine-induced lymphocyte trapping, which is an antigen-specific response that becomes more pronounced with repeated vaccination. Overall, these MRI techniques can provide useful early feedback on vaccination strategies, and could also be used in decision making to select responders from non-responders early in therapy.

  6. Double-reconnected magnetic structures driven by Kelvin-Helmholtz vortices at the Earth's magnetosphere

    Science.gov (United States)

    Faganello, Matteo; Borgogno, Dario; Califano, Francesco; Pegoraro, Francesco

    2015-11-01

    In an almost collisionless MagnetoHydrodynamic plasma in a relatively strong magnetic field, stresses can be conveyed far from the region where they are exerted e.g., through the propagation of Alfvèn waves. The forced dynamics of line-tied magnetic structures in solar and stellar coronae is a paradigmatic case. We investigate how this action at a distance develops from the equatorial region of the Kelvin-Helmholtz unstable flanks of the Earth's magnetosphere leading to the onset, at mid latitude in both hemispheres, of correlated double magnetic field line reconnection events that can allow the solar wind plasma to enter the Earth's magnetosphere. This mid-latitude double reconnection process, first investigated in, has been confirmed here by following a large set of individual field lines using a method similar to a Poincarè map.

  7. Magnetic resonance imaging of large chromophobe renal cell carcinomas

    International Nuclear Information System (INIS)

    Sasaguri, Kohei; Irie, Hiroyuki; Kamochi, Noriyuki; Nakazono, Takahiko; Yamaguchi, Ken; Uozumi, Jiro; Kudo, Sho

    2010-01-01

    The objective of this study was to clarify the magnetic resonance imaging (MRI) findings of large chromophobe renal cell carcinomas. Five patients diagnosed pathologically with chromophobe renal cell carcinoma are included. MRI findings were retrospectively evaluated for the tumor contour, uniformity and hypointensity of the rim of the tumor on T2-weighted images, ''micro-scopic fat'', enhancement degree and pattern on dynamic study, and necrosis in the tumor, among other findings. The tumor size ranged from 4.8 to 13.7 cm (mean 7.9 cm). The tumor contour was well defined in four patients. All but one tumor showed a hypointensity rim, and all tumors had a heterogeneous appearance on T2-weighted images. ''Microscopic fat'' was detected in one case. All tumors demonstrated low enhancement compared to that of the renal cortex. All tumors showed heterogeneous enhancement on postcontrast images. Necrosis was seen in four. Hemorrhage and renal vein thrombosis was seen in one. Chromophobe renal cell carcinomas of large size tend to have a heterogeneous appearance on post-contrast and T2-weighted images, a well-defined tumor contour with a hypointensity rim on T2-wighted images, and lower enhancement than that of the renal cortex. Tumor necrosis is easily apparent, and ''microscopic fat'' may be observed. (author)

  8. Time differentiated nuclear resonance spectroscopy coupled with pulsed laser heating in diamond anvil cells

    Energy Technology Data Exchange (ETDEWEB)

    Kupenko, I., E-mail: kupenko@esrf.fr; Strohm, C. [Bayerisches Geoinstitut, Universität Bayreuth, D-95440 Bayreuth (Germany); ESRF-The European Synchrotron, CS 40220, 38043 Grenoble Cedex 9 (France); McCammon, C.; Cerantola, V.; Petitgirard, S.; Dubrovinsky, L. [Bayerisches Geoinstitut, Universität Bayreuth, D-95440 Bayreuth (Germany); Glazyrin, K. [Photon Science, DESY, D-22607 Hamburg (Germany); Vasiukov, D.; Aprilis, G. [Laboratory of Crystallography, Material Physics and Technology at Extreme Conditions, Universität Bayreuth, D-95440 Bayreuth (Germany); Chumakov, A. I.; Rüffer, R. [ESRF-The European Synchrotron, CS 40220, 38043 Grenoble Cedex 9 (France)

    2015-11-15

    Developments in pulsed laser heating applied to nuclear resonance techniques are presented together with their applications to studies of geophysically relevant materials. Continuous laser heating in diamond anvil cells is a widely used method to generate extreme temperatures at static high pressure conditions in order to study the structure and properties of materials found in deep planetary interiors. The pulsed laser heating technique has advantages over continuous heating, including prevention of the spreading of heated sample and/or the pressure medium and, thus, a better stability of the heating process. Time differentiated data acquisition coupled with pulsed laser heating in diamond anvil cells was successfully tested at the Nuclear Resonance beamline (ID18) of the European Synchrotron Radiation Facility. We show examples applying the method to investigation of an assemblage containing ε-Fe, FeO, and Fe{sub 3}C using synchrotron Mössbauer source spectroscopy, FeCO{sub 3} using nuclear inelastic scattering, and Fe{sub 2}O{sub 3} using nuclear forward scattering. These examples demonstrate the applicability of pulsed laser heating in diamond anvil cells to spectroscopic techniques with long data acquisition times, because it enables stable pulsed heating with data collection at specific time intervals that are synchronized with laser pulses.

  9. Magnetic resonance imaging, percentage of dense cells and serum prostanoids as tools for objective assessment of pain crisis

    International Nuclear Information System (INIS)

    Mankad, V.N.; Williams, J.P.; Harpen, M.; Longenecker, G.; Brogdon, B.; Moore, B.

    1987-01-01

    Magnetic resonance imaging (MRI) has added a new dimension to the identification of soft tissue abnormalities. Chemical and histological characteristics of the tissues can be separated by computerized reconstruction algorithms which produce images and quantitative data. This technique, which is now becoming available in many centers, determines the density of protons of hydrogen in various tissues. If the infarction of the tissues leads to changes in chemical composition of the cells, it may produce changes in the image or in the quantitative data about the resonance of protons. Studies correlating hematologic parameters, radiologic changes in the bones or bone marrow and pain crises are scarce. It is likely that presence of abnormal hemoglobin in the red cell, which produces changes in red cells and rheology of blood, would produce changes in hematological parameters and MRI during pain crisis. The authors, therefore, undertook an evaluation of MRI of bones in sickle cell patients during pain-free and painful periods and obtained measurements of dense sickle cells and prostanoids derived from platelets and endothelium

  10. Cancer cell uptake behavior of Au nanoring and its localized surface plasmon resonance induced cell inactivation

    International Nuclear Information System (INIS)

    Chu, Che-Kuan; Tu, Yi-Chou; Chang, Yu-Wei; Chu, Chih-Ken; Chen, Shih-Yang; Chi, Ting-Ta; Kiang, Yean-Woei; Yang, Chih-Chung

    2015-01-01

    Au nanorings (NRIs), which have the localized surface plasmon resonance (LSPR) wavelength around 1058 nm, either with or without linked antibodies, are applied to SAS oral cancer cells for cell inactivation through the LSPR-induced photothermal effect when they are illuminated by a laser of 1065 nm in wavelength. Different incubation times of cells with Au NRIs are considered for observing the variations of cell uptake efficiency of Au NRI and the threshold laser intensity for cell inactivation. In each case of incubation time, the cell sample is washed for evaluating the total Au NRI number per cell adsorbed and internalized by the cells based on inductively coupled plasma mass spectrometry measurement. Also, the Au NRIs remaining on cell membrane are etched with KI/I 2 solution to evaluate the internalized Au NRI number per cell. The threshold laser intensities for cell inactivation before washout, after washout, and after KI/I 2 etching are calibrated from the circular area sizes of inactivated cells around the illuminated laser spot center with various laser power levels. By using Au NRIs with antibodies, the internalized Au NRI number per cell increases monotonically with incubation time up to 24 h. However, the number of Au NRI remaining on cell membrane reaches a maximum at 12 h in incubation time. The cell uptake behavior of an Au NRI without antibodies is similar to that with antibodies except that the uptake NRI number is significantly smaller and the incubation time for the maximum NRI number remaining on cell membrane is delayed to 20 h. By comparing the threshold laser intensities before and after KI/I 2 etching, it is found that the Au NRIs remaining on cell membrane cause more effective cancer cell inactivation, when compared with the internalized Au NRIs. (paper)

  11. Gratings for synchrotron and FEL beamlines: a project for the manufacture of ultra-precise gratings at Helmholtz Zentrum Berlin.

    Science.gov (United States)

    Siewert, F; Löchel, B; Buchheim, J; Eggenstein, F; Firsov, A; Gwalt, G; Kutz, O; Lemke, St; Nelles, B; Rudolph, I; Schäfers, F; Seliger, T; Senf, F; Sokolov, A; Waberski, Ch; Wolf, J; Zeschke, T; Zizak, I; Follath, R; Arnold, T; Frost, F; Pietag, F; Erko, A

    2018-01-01

    Blazed gratings are of dedicated interest for the monochromatization of synchrotron radiation when a high photon flux is required, such as, for example, in resonant inelastic X-ray scattering experiments or when the use of laminar gratings is excluded due to too high flux densities and expected damage, for example at free-electron laser beamlines. Their availability became a bottleneck since the decommissioning of the grating manufacture facility at Carl Zeiss in Oberkochen. To resolve this situation a new technological laboratory was established at the Helmholtz Zentrum Berlin, including instrumentation from Carl Zeiss. Besides the upgraded ZEISS equipment, an advanced grating production line has been developed, including a new ultra-precise ruling machine, ion etching technology as well as laser interference lithography. While the old ZEISS ruling machine GTM-6 allows ruling for a grating length up to 170 mm, the new GTM-24 will have the capacity for 600 mm (24 inch) gratings with groove densities between 50 lines mm -1 and 1200 lines mm -1 . A new ion etching machine with a scanning radiofrequency excited ion beam (HF) source allows gratings to be etched into substrates of up to 500 mm length. For a final at-wavelength characterization, a new reflectometer at a new Optics beamline at the BESSY-II storage ring is under operation. This paper reports on the status of the grating fabrication, the measured quality of fabricated items by ex situ and in situ metrology, and future development goals.

  12. High Performing Ternary Solar Cells through Förster Resonance Energy Transfer between Nonfullerene Acceptors.

    Science.gov (United States)

    Yang, Lei; Gu, Wenxing; Hong, Ling; Mi, Yang; Liu, Feng; Liu, Ming; Yang, Yufei; Sharma, Bigyan; Liu, Xinfeng; Huang, Hui

    2017-08-16

    Nonradiative Förster resonance energy transfer (FRET) is an important mechanism of organic solar cells, which can improve the exciton migration over a long distance, resulting in improvement of efficiency of solar cells. However, the current observations of FRET are very limited, and the efficiencies are less than 9%. In this study, FRET effect was first observed between two nonfullerene acceptors in ternary solar cells, which improved both the absorption range and exciton harvesting, leading to the dramatic enhancement in the short circuit current and power conversion efficiency. Moreover, this strategy is proved to be a versatile platform for conjugated polymers with different bandgaps, resulting in a remarkable efficiency of 10.4%. These results demonstrated a novel method to enhance the efficiency of organic soar cells.

  13. Patch Antenna based on a Photovoltaic Cell with a Dual resonance Frequency

    Directory of Open Access Journals (Sweden)

    C. Baccouch

    2016-11-01

    Full Text Available The present work was to use photovoltaic solar cells in patch antenna structures. The radiating patch element of a patch antenna was replaced by a solar cell. Direct Current (DC generation remained the original feature of the solar cell, but additionally   it was now able to receive and transmit electromagnetic waves. Here, we used a new patch antenna structure based on a photovoltaic solar cell. It was then used to collect photo-generated current as well as Radio Frequency (RF transmission. A mathematical model which would serve the minimization of power losses of the cell and therefore the improvement in the conversion efficiency was studied. A simulation allowed analysing the performance of the antenna, with a silicon material, and testing its parameters such as the reflection coefficient (S11, gain, directivity and radiated power. The performance analysis of the solar cell patch antenna was conducted using Advanced Design System (ADS software. Simulation results for this antenna showed a dual resonance frequency of 5.77 GHz and of 6.18 GHz with an effective return loss of -38.22dB and a gain of 1.59dBi.

  14. Stability of a modified Peaceman–Rachford method for the paraxial Helmholtz equation on adaptive grids

    Energy Technology Data Exchange (ETDEWEB)

    Sheng, Qin, E-mail: Qin_Sheng@baylor.edu [Department of Mathematics and Center for Astrophysics, Space Physics and Engineering Research, Baylor University, One Bear Place, Waco, TX 76798-7328 (United States); Sun, Hai-wei, E-mail: hsun@umac.mo [Department of Mathematics, University of Macau (Macao)

    2016-11-15

    This study concerns the asymptotic stability of an eikonal, or ray, transformation based Peaceman–Rachford splitting method for solving the paraxial Helmholtz equation with high wave numbers. Arbitrary nonuniform grids are considered in transverse and beam propagation directions. The differential equation targeted has been used for modeling propagations of high intensity laser pulses over a long distance without diffractions. Self-focusing of high intensity beams may be balanced with the de-focusing effect of created ionized plasma channel in the situation, and applications of grid adaptations are frequently essential. It is shown rigorously that the fully discretized oscillation-free decomposition method on arbitrary adaptive grids is asymptotically stable with a stability index one. Simulation experiments are carried out to illustrate our concern and conclusions.

  15. Microspectroscopic Study of Liposome-to-cell Interaction Revealed by Förster Resonance Energy Transfer.

    Science.gov (United States)

    Yefimova, Svetlana L; Kurilchenko, Irina Yu; Tkacheva, Tatyana N; Kavok, Nataliya S; Todor, Igor N; Lukianova, Nataliya Yu; Chekhun, Vasyl F; Malyukin, Yuriy V

    2014-03-01

    We report the Förster resonance energy transfer (FRET)-labeling of liposomal vesicles as an effective approach to study in dynamics the interaction of liposomes with living cells of different types (rat hepatocytes, rat bone marrow, mouse fibroblast-like cells and human breast cancer cells) and cell organelles (hepatocyte nuclei). The in vitro experiments were performed using fluorescent microspectroscopic technique. Two fluorescent dyes (DiO as the energy donor and DiI as an acceptor) were preloaded in lipid bilayers of phosphatidylcholine liposomes that ensures the necessary distance between the dyes for effective FRET. The change in time of the donor and acceptor relative fluorescence intensities was used to visualize and trace the liposome-to-cell interaction. We show that FRET-labeling of liposome vesicles allows one to reveal the differences in efficiency and dynamics of these interactions, which are associated with composition, fluidity, and metabolic activity of cell plasma membranes.

  16. Sound attenuations of axial fan blade tones using flow-driven tunable resonator arrays

    Science.gov (United States)

    Gorny, Lee James

    Flow-excited, tunable quarter-wavelength resonators can be integrated into the shrouds of ducted subsonic axial fans. This study explores their effectiveness in reducing propagations of tonal noise by means of acoustic wave cancellation. Resonators are a non-intrusive method of generating a secondary sound field near the plane of a rotor. As they can be strategically tuned to reduce radiated noise at the blade passage frequency (BPF) and its harmonics, resonators can be useful for a variety of applications to quiet existing and future turbomachinery. Experiments have demonstrated that a single quarter wave resonator is effective in reducing unidirectional plane wave propagations for long wavelength ducted applications while an array is effective for shorter wavelength or un-ducted facilities where shrouded fans are used. Testing conducted at Center for Acoustics and Vibrations (CAV) at the Pennsylvania State University the Deutsches Zentrum fur Luft und Raumfahrt (DLR) in Berlin, Germany demonstrated that resonator arrays were effective in attenuating shorter wavelength plane-wave and higher order modal propagations of blade tone noise. A chiller fan enclosure, constructed in the CAV laboratory emulated an industrial chiller in its operation. Using this facility, resonators were observed to attenuate blade tone noise from a non-ideal ducted geometry. The approaches used in this study evolved from Helmholtz resonators to conventional quarter wave tubes, to mouth tunable resonators, and finally to back-wall tunable resonators. These developments in tuning allowed for independent control of a resonator's magnitude and phase of the secondary sound field produced by the resonators. It was demonstrated that the use of two tunable resonator chambers oriented axially on either side of the blade region enables a dipole-like secondary sound field to be passively generated and bi-directional attenuations of plane wave noise to be achieved. Tonal attenuations of 28 dB were

  17. Kelvin-Helmholtz instability and kinetic internal kink modes in tokamaks

    International Nuclear Information System (INIS)

    Naitou, H.; Kobayashi, T.; Yagi, M.; Matsumoto, T.; Tokuda, S.; Kishimoto, Y.

    2003-01-01

    The m=1 (poloidal mode number) and n=1 (toroidal mode number) kinetic internal kink (KIK) mode in the presence of a density gradient is studied with the cylindrical version of the gyro-reduced MHD code, which is one of the extended MHD codes being able to treat the physics beyond resistive MHD. Electron inertia and electron finite temperature effects are included. The unstable KIK mode is observed in the parameter range in which the linear theory predicts complete stabilization due to the electron diamagnetic effect. The electrostatic potential profile in the linear stage of the KIK instability has the sheared poloidal flow with the m=1 mode structure. The vortexes are generated due to the Kelvin-Helmholtz (K-H) instability. The KIK is stabilized when the vortexes are formed, but it is destabilized again as the vortexes diminish due to the charge neutralizing electron motion along the magnetic field. These phenomena are observed in the early nonlinear stage of the KIK instability in which the width of the m=1 magnetic island is sufficiently small compared with the radial extent of the vortexes. The strong coupling between the vortexes and the KIK instability can be one of the candidates explaining the sudden onset of the sawtooth crash. (author)

  18. Response of the 1P0 resonance near n = 3 in the H- continuum to external electric fields

    International Nuclear Information System (INIS)

    Cohen, S.

    1986-05-01

    The response to external electric fields of the 1 P 0 resonance in the H - photodetachment continuum below the n = 3 hydrogenic excitation threshold is investigated. Using the relativistic (β = 0.806) 650 MeV H - beam at the Clinton P. Anderson Meson Physics Facility (LAMPF) in Los Alamos, the fourth harmonic (2.66 nm) of a Nd:YAG laser is Doppler shifted to provide a continuously tunable photon beam in the rest frame of the ions. The magnetic field from pulsed Helmholtz coils, surrounding the photon-H - interaction point provides a Lorentz-transformed barycentric electric field. Relative total photodetachment cross sections were measured as a function of photon energy and electric field. The resulting spectra were fit to a Fano line shape. 70 refs., 28 figs., 7 tabs

  19. Kelvin-Helmholtz instability in type-1 comet tails and associated phenomena

    International Nuclear Information System (INIS)

    Ershkovich, A.I.

    1980-01-01

    Selected problems of the solar wind - comet tail coupling that are currently accessible to quantitative analysis are reviewed. The model of a comet tail as a plasma cylinder separated by a tangential discontinuity surface from the solar wind is discussed in detail. This model is compatible with the well-known Alfven mechanism of formation of the comet tail. The stability problem of the comet tail boundary (considered as a discontinuity surface) is solved. Under typical conditions a comet tail boundary can undergo the Kelvin-Helmholtz instability. With finite amplitude the stabilizing effect of the magnetic field increases, and waves become stabilized. This model supplies a detailed quantitative description of helical waves observed in type-1 comet tails. A more general model of the tail boundary as a transition layer with a continuous change of the plasma parameters within it is also considered. This theory, in principle, enables us to solve one of the fundamental problems of cometary physics: the magnetic field of the comet tail can be derived from the observations of helical waves. This field turns out to be of the order of the interplanetary field. Various other considerations, discussed in this review also support this conclusion. (orig.)

  20. Electromagnetically induced transparency resonances inverted in magnetic field

    Energy Technology Data Exchange (ETDEWEB)

    Sargsyan, A.; Sarkisyan, D., E-mail: davsark@yahoo.com, E-mail: david@ipr.sci.am [National Academy of Sciences of Armenia, Institute for Physical Research (Armenia); Pashayan-Leroy, Y.; Leroy, C. [Université de Bourgogne-Dijon, Laboratoire Interdisciplinaire Carnot de Bourgogne, UMR CNRS (France); Cartaleva, S. [Bulgarian Academy of Sciences, Institute of Electronics (Bulgaria); Wilson-Gordon, A. D. [Bar-Ilan University Ramat Gan, Department of Chemistry (Israel); Auzinsh, M. [University of Latvia, Department of Physics (Latvia)

    2015-12-15

    The phenomenon of electromagnetically induced transparency (EIT) is investigated in a Λ-system of the {sup 87}Rb D{sub 1} line in an external transverse magnetic field. Two spectroscopic cells having strongly different values of the relaxation rates γ{sub rel} are used: an Rb cell with antirelaxation coating (L ∼ 1 cm) and an Rb nanometric- thin cell (nanocell) with a thickness of the atomic vapor column L = 795 nm. For the EIT in the nanocell, we have the usual EIT resonances characterized by a reduction in the absorption (dark resonance (DR)), whereas for the EIT in the Rb cell with an antirelaxation coating, the resonances demonstrate an increase in the absorption (bright resonances (BR)). We suppose that such an unusual behavior of the EIT resonances (i.e., the reversal of the sign from DR to BR) is caused by the influence of an alignment process. The influence of alignment strongly depends on the configuration of the coupling and probe frequencies as well as on the configuration of the magnetic field.

  1. Superparamagnetic iron oxide nanoparticle-labeled cells as an effective vehicle for tracking the GFP gene marker using magnetic resonance imaging

    Science.gov (United States)

    Zhang, Z; Mascheri, N; Dharmakumar, R; Fan, Z; Paunesku, T; Woloschak, G; Li, D

    2010-01-01

    Background Detection of a gene using magnetic resonance imaging (MRI) is hindered by the magnetic resonance (MR) targeting gene technique. Therefore it may be advantageous to image gene-expressing cells labeled with superparamagnetic iron oxide (SPIO) nanoparticles by MRI. Methods The GFP-R3230Ac (GFP) cell line was incubated for 24 h using SPIO nanoparticles at a concentration of 20 μg Fe/mL. Cell samples were prepared for iron content analysis and cell function evaluation. The labeled cells were imaged using fluorescent microscopy and MRI. Results SPIO was used to label GFP cells effectively, with no effects on cell function and GFP expression. Iron-loaded GFP cells were successfully imaged with both fluorescent microscopy and T2*-weighted MRI. Prussian blue staining showed intracellular iron accumulation in the cells. All cells were labeled (100% labeling efficiency). The average iron content per cell was 4.75±0.11 pg Fe/cell (P<0.05 versus control). Discussion This study demonstrates that the GFP expression of cells is not altered by the SPIO labeling process. SPIO-labeled GFP cells can be visualized by MRI; therefore, GFP, a gene marker, was tracked indirectly with the SPIO-loaded cells using MRI. The technique holds promise for monitoring the temporal and spatial migration of cells with a gene marker and enhancing the understanding of cell- and gene-based therapeutic strategies. PMID:18956269

  2. Magnetohydrodynamic Kelvin-Helmholtz instabilities in astrophysics. 3. Hydrodynamic flows with shear layers

    Energy Technology Data Exchange (ETDEWEB)

    Ferraro, A [Consiglio Nazionale delle Ricerche, Turin (Italy). Lab. di Cosmo-Geofisica; Max-Planck-Institut fuer Extraterrestrische Physik, Garching (Germany, F.R.)); Massaglia, S [Turin Univ. (Italy). Ist. di Fisica; Trussoni, E [Consiglio Nazionale delle Ricerche, Turin (Italy). Lab. di Cosmo-Geofisica

    1982-03-01

    In this paper a discussion is presented on Kelvin-Helmholtz instabilities in pressure-confined two-dimensional flows (slabs) delimited by boundary layers with velocity and density gradients. It is found that the fastest growing modes in supersonic flows are produced by perturbations reflecting at the boundaries and have wavelengths of the order of the slab width; this peak of instability is even more evident than in the case of vortex-sheet cylindrical flows, discussed in a previous paper. From a comparison of the results for the two-dimensional slab and three-dimensional cylinder it is concluded that a two-dimensional treatment provides an adequate description of instabilities in fluid flows. In this analogy, symmetric and antisymmetric modes in the slab correspond to pinching and helical modes in the cylinder. In the final section a comparison is attempted of the results obtained with morphologies in collimated jets in extragalactic radio sources; general characteristics appear to be classifiable in terms of scale-lengths of the velocity and density gradients in the boundary layers.

  3. Double-reconnected magnetic structures driven by Kelvin-Helmholtz vortices at the Earth's magnetosphere

    International Nuclear Information System (INIS)

    Borgogno, D.; Califano, F.; Pegoraro, F.; Faganello, M.

    2015-01-01

    In an almost collisionless magnetohydrodynamic plasma in a relatively strong magnetic field, stresses can be conveyed far from the region where they are exerted, e.g., through the propagation of Alfvèn waves. The forced dynamics of line-tied magnetic structures in solar and stellar coronae (see, e.g., A. F. Rappazzo and E. N. Parker, Astrophys. J. 773, L2 (2013) and references therein) is a paradigmatic case. Here, we investigate how this action at a distance develops from the equatorial region of the Kelvin-Helmholtz unstable flanks of the Earth's magnetosphere leading to the onset, at mid latitude in both hemispheres, of correlated double magnetic field line reconnection events that can allow the solar wind plasma to enter the Earth's magnetosphere

  4. Extracting the potential-well of a near-field optical trap using the Helmholtz-Hodge decomposition

    Science.gov (United States)

    Zaman, Mohammad Asif; Padhy, Punnag; Hansen, Paul C.; Hesselink, Lambertus

    2018-02-01

    The non-conservative nature of the force field generated by a near-field optical trap is analyzed. A plasmonic C-shaped engraving on a gold film is considered as the trap. The force field is calculated using the Maxwell stress tensor method. The Helmholtz-Hodge decomposition is used to extract the conservative and the non-conservative component of the force. Due to the non-negligible non-conservative component, it is found that the conventional approach of extracting the potential by direct integration of the force is not accurate. Despite the non-conservative nature of the force field, it is found that the statistical properties of a trapped nanoparticle can be estimated from the conservative component of the force field alone. Experimental and numerical results are presented to support the claims.

  5. Resonances and anti-resonances in the material parameters of 2-D dielectric ENG, MNG, and DNG materials

    DEFF Research Database (Denmark)

    Wu, Yunqiu; Arslanagic, Samel

    The resonant/anti-resonant behavior of parameters extracted by the S-parameter method for two-dimensional epsilon-, mu- and double-negative (ENG, MNG, DNG) materials is investigated. The unit cells consist of infinite dielectric cylinders supporting electric dipole, magnetic dipole, or both....... It is shown that the extraction procedure yields one resonant material parameter, and one anti-resonant material parameter in MNG and ENG configurations. However, both parameters display an over-all resonant response in DNG configurations where electric and magnetic dipole modes are excited simultaneously....

  6. Resonance – Journal of Science Education | Indian Academy of ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education. Yasmin Khan. Articles written in Resonance – Journal of Science Education. Volume 7 Issue 1 January 2002 pp 4-10 Series Article. Glial Cells: The Other Cells of the Nervous System - An Introduction to Glial Cells · Medha S Rajadhyaksha Yasmin Khan.

  7. Magnetic resonance imaging aspects of giant-cell tumours of bone

    International Nuclear Information System (INIS)

    Pereira, Helcio Mendoncça; Marchiori, Edson; Severo, Alessandro

    2014-01-01

    This study aimed to describe the magnetic resonance imaging (MRI) features of giant-cell tumours of bone. We analysed the clinical and MRI features of patients diagnosed with giant-cell tumours of bone confirmed by histopathology at our institution between 2010 and 2012. The peak incidence was between the second and third decades of life. There was no gender predominance. The most frequent locations were the knee and wrist. Pain and swelling were the prevailing symptoms. Fifty-one per cent of the patients were found to have associated secondary aneurysmal bone cysts on histopathology. On MRI, lesions demonstrated signal intensity equal to that of skeletal muscle on T1-weighted images and low signal intensity on T2-weighted images in 90% of cases. In gadolinium-enhanced T1-weighted images, 76.6% of cases demonstrated heterogeneous enhancement. We observed cystic components involving more than 50% of the lesion in 17 cases (56.6%). There was extra-osseous involvement in 13 cases (43.3%). MRI offers a valuable diagnostic tool for giant-cell tumours of bone. Contrast-enhanced MRI can distinguish between cystic and solid components of the tumour. MRI is also the imaging modality of choice for evaluation of soft-tissue involvement, offering a complete preoperative diagnosis.

  8. Bringing new archival sources to Wundt scholarship: the case of Wundt's assistantship with Helmholtz.

    Science.gov (United States)

    Araujo, Saulo de Freitas

    2014-02-01

    Wilhelm Wundt's biography is one of the main domains in Wundt scholarship that deserves more detailed attention. The few existing biographical works present many problems, ranging from vagueness to chronological inaccuracies, among others. One of the important gaps concerns the so-called Heidelberg period (1852-1874), during which he went from being a medical student to holding a professorship at the University of Heidelberg. The aim of this article is to dispel a very common confusion in the secondary literature, which refers to Wundt's assistantship with Helmholtz at the Physiological Institute, by establishing the precise dates of his assistantship. Contrary to what is generally repeated in the secondary literature, the primary sources allow us to determine precisely this period from October 1858 to March 1865. I conclude by pointing out the indispensability of the primary sources not only to Wundt scholarship but also to the historiography of psychology in general.

  9. The evolution of a localized nonlinear wave of the Kelvin-Helmholtz instability with gravity

    Science.gov (United States)

    Orazzo, Annagrazia; Hoepffner, Jérôme

    2012-11-01

    At the interface between two fluids of different density and in the presence of gravity, there are well known periodic surface waves which can propagate for long distances with little attenuation, as it is for instance the case at the surface of the sea. If wind is present, these waves progressively accumulate energy as they propagate and grow to large sizes—this is the Kelvin-Helmholtz instability. On the other hand, we show in this paper that for a given wind strength, there is potential for the growth of a localized nonlinear wave. This wave can reach a size such that the hydrostatic pressure drop from top to bottom equals the stagnation pressure of the wind. This process for the disruption of the flat interface is localized and nonlinear. We study the properties of this wave using numerical simulations of the Navier-Stokes equations.

  10. Progressive and resonant wave helices application to electron paramagnetic resonance; Helices a ondes progressives et resonnantes application a la resonance paramagnetique electronique

    Energy Technology Data Exchange (ETDEWEB)

    Volino, F [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1969-07-01

    We show that helices can be used as resonant systems. Their properties are theoretically and experimentally studied. We describe resonant helices for electron paramagnetic resonance in X-band and develop a comparison between their sensitivity and the sensitivity of a normal resonant cavity. For cylindrical samples less than 3 mm diameter, the helix is more sensitive and can produce more intense microwave magnetic fields. (author) [French] Il est montre que les helices peuvent etre utilisees comme systeme resonnant. Leurs proprietes sont discutees theoriquement et experimentalement. Des helices resonnantes en bande X pour la resonance paramagnetique electronique sont decrites et leur sensibilite est comparee a celle des cavites resonnantes. Pour des echantillons cylindriques de moins de 3 mm de diametre, l'helice est plus sensible et peut produire des champs magnetiques hyper fins plus intenses. (auteur)

  11. Modeling the efficiency of Förster resonant energy transfer from energy relay dyes in dye-sensitized solar cells

    KAUST Repository

    Hoke, Eric T.; Hardin, Brian E.; McGehee, Michael D.

    2010-01-01

    Förster resonant energy transfer can improve the spectral breadth, absorption and energy conversion efficiency of dye sensitized solar cells. In this design, unattached relay dyes absorb the high energy photons and transfer the excitation

  12. Magnetic resonance cell-tracking studies: spectrophotometry-based method for the quantification of cellular iron content after loading with superparamagnetic iron oxide nanoparticles.

    Science.gov (United States)

    Böhm, Ingrid

    2011-08-01

    The purpose of this article is to present a user-friendly tool for quantifying the iron content of superparamagnetic labeled cells before cell tracking by magnetic resonance imaging (MRI). Iron quantification was evaluated by using Prussian blue staining and spectrophotometry. White blood cells were labeled with superparamagnetic iron oxide (SPIO) nanoparticles. Labeling was confirmed by light microscopy. Subsequently, the cells were embedded in a phantom and scanned on a 3 T magnetic resonance tomography (MRT) whole-body system. Mean peak wavelengths λ(peak) was determined at A(720 nm) (range 719-722 nm). Linearity was proven for the measuring range 0.5 to 10 μg Fe/mL (r  =  .9958; p  =  2.2 × 10(-12)). The limit of detection was 0.01 μg Fe/mL (0.1785 mM), and the limit of quantification was 0.04 μg Fe/mL (0.714 mM). Accuracy was demonstrated by comparison with atomic absorption spectrometry. Precision and robustness were also proven. On T(2)-weighted images, signal intensity varied according to the iron concentration of SPIO-labeled cells. Absorption spectrophotometry is both a highly sensitive and user-friendly technique that is feasible for quantifying the iron content of magnetically labeled cells. The presented data suggest that spectrophotometry is a promising tool for promoting the implementation of magnetic resonance-based cell tracking in routine clinical applications (from bench to bedside).

  13. Magnetic Resonance Cell-Tracking Studies: Spectrophotometry-Based Method for the Quantification of Cellular Iron Content after Loading with Superparamagnetic Iron Oxide Nanoparticles

    Directory of Open Access Journals (Sweden)

    Ingrid Böhm

    2011-07-01

    Full Text Available The purpose of this article is to present a user-friendly tool for quantifying the iron content of superparamagnetic labeled cells before cell tracking by magnetic resonance imaging (MRI. Iron quantification was evaluated by using Prussian blue staining and spectrophotometry. White blood cells were labeled with superparamagnetic iron oxide (SPIO nanoparticles. Labeling was confirmed by light microscopy. Subsequently, the cells were embedded in a phantom and scanned on a 3 T magnetic resonance tomography (MRT whole-body system. Mean peak wavelengths Λpeak was determined at A720nm (range 719–722 nm. Linearity was proven for the measuring range 0.5 to 10 μg Fe/mL (r = .9958; p = 2.2 × 10−12. The limit of detection was 0.01 μg Fe/mL (0.1785 mM, and the limit of quantification was 0.04 μg Fe/mL (0.714 mM. Accuracy was demonstrated by comparison with atomic absorption spectrometry. Precision and robustness were also proven. On T2-weighted images, signal intensity varied according to the iron concentration of SPIO-labeled cells. Absorption spectrophotometry is both a highly sensitive and user-friendly technique that is feasible for quantifying the iron content of magnetically labeled cells. The presented data suggest that spectrophotometry is a promising tool for promoting the implementation of magnetic resonance-based cell tracking in routine clinical applications (from bench to bedside.

  14. T cell homing to tumors detected by 3D-coordinated positron emission tomography and magnetic resonance imaging

    DEFF Research Database (Denmark)

    Agger, Ralf; Petersen, Mikkel; Petersen, Charlotte Christie

    2007-01-01

    of magnetic resonance imaging with the high sensitivity and spatial accuracy of positron emission tomography. We have used this technique, together with determination of tissue radioactivity, flow cytometry, and microscopy, to characterize and quantitate the specific accumulation of transferred CD8+ T cells...

  15. Ultrasound imparted air-recoil resonance (UIAR) method for acoustic power estimation: theory and experiment.

    Science.gov (United States)

    Kaiplavil, Sreekumar; Rivens, Ian; ter Haar, Gail

    2013-07-01

    Ultrasound imparted air-recoil resonance (UIAR), a new method for acoustic power estimation, is introduced with emphasis on therapeutic high-intensity focused ultrasound (HIFU) monitoring applications. Advantages of this approach over existing practices include fast response; electrical and magnetic inertness, and hence MRI compatibility; portability; high damage threshold and immunity to vibration and interference; low cost; etc. The angle of incidence should be fixed for accurate measurement. However, the transducer-detector pair can be aligned in any direction with respect to the force of gravity. In this sense, the operation of the device is orientation independent. The acoustic response of a pneumatically coupled pair of Helmholtz resonators, with one of them acting as the sensor head, is used for the estimation of acoustic power. The principle is valid in the case of pulsed/ burst as well as continuous ultrasound exposure, the former being more sensitive and accurate. An electro-acoustic theory has been developed for describing the dynamics of pressure flow and resonance in the system considering various thermo- viscous loss mechanisms. Experimental observations are found to be in agreement with theoretical results. Assuming the window damage threshold (~10 J·mm(-2)) and accuracy of RF power estimation are the upper and lower scale-limiting factors, the performance of the device was examined for an RF power range of 5 mW to 100 W with a HIFU transducer operating at 1.70 MHz, and an average nonlinearity of ~1.5% was observed. The device is also sensitive to sub-milliwatt powers. The frequency response was analyzed at 0.85, 1.70, 2.55, and 3.40 MHz and the results are presented with respective theoretical estimates. Typical response time is in the millisecond regime. Output drift is about 3% for resonant and 5% for nonresonant modes. The principle has been optimized to demonstrate a general-purpose acoustic power meter.

  16. New sub-Doppler absorption resonances in a thin gas cell produced by means of a running monochromatic wave

    International Nuclear Information System (INIS)

    Tajalli, H; Ahmadi, S; Izmailov, A Ch

    2002-01-01

    A theoretical investigation is carried out through the interaction of the plane running monochromatic light wave, having an arbitrary intensity, with atoms (molecules) of a rarefied gas in the plane cell (at the normal incidence of the wave). Cases of closed and open resonance transitions from the non-degenerate ground (or metastable) quantum level are considered. Possible sub-Doppler resonances are analysed in the wave absorption, caused by the transient establishment of the optical coherence on the transition, Rabi oscillations between its levels, and optical pumping during the free flights of particles between the walls of the cell. Results of the previous works on given problems are generalized, which were obtained at definite restrictions on the wave intensity and cell length. Moreover, non-trivial sub-Doppler spectral structures, resulting as a consequence of the dependence of the absorption saturation on the transit relaxation of particles, have been established and investigated. Such structures may consist of a number of peaks and dips caused by Rabi oscillations between the transition levels. The results obtained can be used in sub-Doppler spectroscopy and for the stabilization of laser frequencies in thin gas cells

  17. An Investigation of Hall Currents Associated with Tripolar Magnetic Fields During Magnetospheric Kelvin Helmholtz Waves

    Science.gov (United States)

    Sturner, A. P.; Eriksson, S.; Newman, D. L.; Lapenta, G.; Gershman, D. J.; Plaschke, F.; Ergun, R.; Wilder, F. D.; Torbert, R. B.; Giles, B. L.; Strangeway, R. J.; Russell, C. T.; Burch, J. L.

    2016-12-01

    Kinetic simulations and observations of magnetic reconnection suggest the Hall term of Ohm's Law is necessary for understanding fast reconnection in the Earth's magnetosphere. During high (>1) guide field plasma conditions in the solar wind and in Earth's magnetopause, tripolar variations in the guide magnetic field are often observed during current sheet crossings, and have been linked to reconnection Hall magnetic fields. Two proposed mechanisms for these tripolar variations are the presence of multiple nearby X-lines and magnetic island coalescence. We present results of an investigation into the structure of the electron currents supporting tripolar guide magnetic field variations during Kelvin-Helmholtz wave current sheet crossings using the Magnetosphere Multiscale (MMS) Mission, and compare with bipolar magnetic field structures and with kinetic simulations to understand how these tripolar structures may be used as tracers for magnetic islands.

  18. Hybrid resonant organic-inorganic nanostructures for novel light emitting devices and solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Agranovich, Vladimir M. [Institute of Spectroscopy, Russian Academy of Science, Troitsk, Moscow (Russian Federation); Chemistry Department, University of Texas at Dallas, Texas (United States); Rupasov, Valery I. [ANTEOS, Inc., Shrewsbury, Massachusetts 01545 (United States); Silvestri, Leonardo [Dipartimento di Scienza dei Materiali, Universita degli Studi di Milano Bicocca, Milano (Italy)

    2010-06-15

    The energy transfer from an inorganic layer to an organic component of resonant hybrid organic/inorganic nanos-tructures can be used for creation of new type of LED. We mentioned the problem of electrical pumping which has to be solved. As was first suggested in 1979 by Dexter the transfer energy in opposite direction from organic part of nanostructure to semiconductor layer can be used for the creation of new type of solar cells. In this note we stress the importance of the idea by Dexter for photovoltaics and solar cells. We argue that the organic part in such hybrid structures can play a role of an effective organic collector of the light energy (copyright 2010 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  19. Progressive and resonant wave helices application to electron paramagnetic resonance; Helices a ondes progressives et resonnantes application a la resonance paramagnetique electronique

    Energy Technology Data Exchange (ETDEWEB)

    Volino, F. [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1969-07-01

    We show that helices can be used as resonant systems. Their properties are theoretically and experimentally studied. We describe resonant helices for electron paramagnetic resonance in X-band and develop a comparison between their sensitivity and the sensitivity of a normal resonant cavity. For cylindrical samples less than 3 mm diameter, the helix is more sensitive and can produce more intense microwave magnetic fields. (author) [French] Il est montre que les helices peuvent etre utilisees comme systeme resonnant. Leurs proprietes sont discutees theoriquement et experimentalement. Des helices resonnantes en bande X pour la resonance paramagnetique electronique sont decrites et leur sensibilite est comparee a celle des cavites resonnantes. Pour des echantillons cylindriques de moins de 3 mm de diametre, l'helice est plus sensible et peut produire des champs magnetiques hyper fins plus intenses. (auteur)

  20. Human Aortic Endothelial Cell Labeling with Positive Contrast Gadolinium Oxide Nanoparticles for Cellular Magnetic Resonance Imaging at 7 Tesla

    Directory of Open Access Journals (Sweden)

    Yasir Loai

    2012-03-01

    Full Text Available Positive T1 contrast using gadolinium (Gd contrast agents can potentially improve detection of labeled cells on magnetic resonance imaging (MRI. Recently, gadolinium oxide (Gd2O3 nanoparticles have shown promise as a sensitive T1 agent for cell labeling at clinical field strengths compared to conventional Gd chelates. The objective of this study was to investigate Gado CELLTrack, a commercially available Gd2O3 nanoparticle, for cell labeling and MRI at 7 T. Relaxivity measurements yielded r1 = 4.7 s−1 mM−1 and r2/r1 = 6.2. Human aortic endothelial cells were labeled with Gd2O3 at various concentrations and underwent MRI from 1 to 7 days postlabeling. The magnetic resonance relaxation times T1 and T2 of labeled cell pellets were measured. Cellular contrast agent uptake was quantified by inductively coupled plasma–atomic emission spectroscopy, which showed very high uptake compared to conventional Gd compounds. MRI demonstrated significant positive T1 contrast and stable labeling on cells. Enhancement was optimal at low Gd concentrations, attained in the 0.02 to 0.1 mM incubation concentration range (corresponding cell uptake was 7.26 to 34.1 pg Gd/cell. Cell viability and proliferation were unaffected at the concentrations tested and up to at least 3 days postlabeling. Gd2O3 is a promising sensitive and stable positive contrast agent for cellular MRI at 7 T.

  1. ESTUDO DA INSTABILIDADE KELVIN-HELMHOLTZ ATRAVÉS DE SIMULAÇÕES COM O CÓDIGO ATHENA

    Directory of Open Access Journals (Sweden)

    Priscila Freitas-Lemes

    2013-12-01

    Full Text Available As instabilidades Kelvin-Helmholtz são comuns em sistemas astrofísicos e vão desde jatos deburacos negros até disco de acreção protoplantário. Um objeto astrofísico com fortes características da instabilidade de Kelvin-Helmholtz é a Nebulosa de Caraguejo, na qual a expansão do material foi ocasionado pela explosão de uma supernova há, aproximadamente, 1000 anos. Essa instabilidade ocorre no limite entre dois fluidos de diferentes densidades, quando um dos fluidos é acelerado com relação ao outro. Com o objetivo de estudar essa instabilidade, realizamos uma simulação com o código de malha euleriana ATHENA. Para essasimulação, consideramos um domínio quadrado com limites periódicos sobre as laterais, e, refletindo na fronteirada parte superior e inferior. A região superior da caixa é preenchida com um gás de densidade ρ=1,0, pressãoP1=1,0, índice adiabático γ=5/3 e velocidade u1=0,03 na direção x (para direita. A parte inferior tem densidadeρ=2,0, mesma pressão, velocidade e índice adiabático, só que no sentido contrário, para a esquerda. A velocidade é definida como uma função senoidal, que cria a perturbação inicial. Como resultado, observamos o princípio da instabilidade e a formação dos vórtices, com as cristas bem definidas. A nitidez da fronteira entre o material de alta e de baixa densidade está bem conservada, devido à difusão relativamente baixa do algoritmo. Notamos, ainda, que, evoluindo a simulação, os vórtices formados a partir da turbulência fundem-se.

  2. Design of all-optical memory cell using EIT and lasing without inversion phenomena in optical micro ring resonators

    Science.gov (United States)

    Pasyar, N.; Yadipour, R.; Baghban, H.

    2017-07-01

    The proposed design of the optical memory unit cell contains dual micro ring resonators in which the effect of lasing without inversion (LWI) in three-level nano particles doped over the optical resonators or integrators as the gain segment is used for loss compensation. Also, an on/off phase shifter based on electromagnetically induced transparency (EIT) in three-level quantum dots (QDs) has been used for data reading at requested time. Device minimizing for integrated purposes and high speed data storage are the main advantages of the optical integrator based memory.

  3. Comparison of magnetic resonance angiography and conventional angiography in sickle cell disease: clinical significance and realibility

    International Nuclear Information System (INIS)

    Kandeel, A.Y.; Zimmerman, R.A.; Ohene-Frempong, K.

    1996-01-01

    We retrospectively reviewed the medical records and conventional angiograms of 21 patients with known sickle cell disease, who underwent a total of 50 magnetic resonance imaging (MRI) and magnetic resonance angiography (MRA) studies. MRA and conventional angiography were assessed separately for evidence of stenosis or occulusion. Follow up MRI/MRA studies were also assessed for evidence of progression, regression or stability of the disease in these patients. In the carotid circulation, MRA made the correct diagnosis in 85% of the vessels evaluated with a sensitivity of 80.5% and a specificity of 94%. MRA was also found to show evidence of disease progression, more often than did MRI or the clinical condition of the patients. (orig.)

  4. Response of the /sup 1/P/sup 0/ resonance near n = 3 in the H/sup -/ continuum to external electric fields

    Energy Technology Data Exchange (ETDEWEB)

    Cohen, S.

    1986-05-01

    The response to external electric fields of the /sup 1/P/sup 0/ resonance in the H/sup -/ photodetachment continuum below the n = 3 hydrogenic excitation threshold is investigated. Using the relativistic (..beta.. = 0.806) 650 MeV H/sup -/ beam at the Clinton P. Anderson Meson Physics Facility (LAMPF) in Los Alamos, the fourth harmonic (2.66 nm) of a Nd:YAG laser is Doppler shifted to provide a continuously tunable photon beam in the rest frame of the ions. The magnetic field from pulsed Helmholtz coils, surrounding the photon-H/sup -/ interaction point provides a Lorentz-transformed barycentric electric field. Relative total photodetachment cross sections were measured as a function of photon energy and electric field. The resulting spectra were fit to a Fano line shape. 70 refs., 28 figs., 7 tabs.

  5. Resonance – Journal of Science Education | Indian Academy of ...

    Indian Academy of Sciences (India)

    Abstract. In this series of articles, the authors discuss various phenomenain fluid dynamics, which may be investigated via tabletopexperiments using low-cost or home-made instruments. Theeighth article in this series explores and demonstratesKelvin–Helmholtz instability.

  6. Observation of the Kelvin–Helmholtz Instability in a Solar Prominence

    Science.gov (United States)

    Yang, Heesu; Xu, Zhi; Lim, Eun-Kyung; Kim, Sujin; Cho, Kyung-Suk; Kim, Yeon-Han; Chae, Jongchul; Cho, Kyuhyoun; Ji, Kaifan

    2018-04-01

    Many solar prominences end their lives in eruptions or abrupt disappearances that are associated with dynamical or thermal instabilities. Such instabilities are important because they may be responsible for energy transport and conversion. We present a clear observation of a streaming kink-mode Kelvin–Helmholtz Instability (KHI) taking place in a solar prominence using the Hα Lyot filter installed at the New Vacuum Solar Telescope, Fuxian-lake Solar Observatory in Yunnan, China. On one side of the prominence, a series of plasma blobs floated up from the chromosphere and streamed parallel to the limb. The plasma stream was accelerated to about 20–60 km s‑1 and then undulated. We found that 2″- and 5″-size vortices formed, floated along the stream, and then broke up. After the 5″-size vortex, a plasma ejection out of the stream was detected in the Solar Dynamics Observatory/Atmospheric Imaging Assembly images. Just before the formation of the 5″-size vortex, the stream displayed an oscillatory transverse motion with a period of 255 s with the amplitude growing at the rate of 0.001 s‑1. We attribute this oscillation of the stream and the subsequent formation of the vortex to the KHI triggered by velocity shear between the stream, guided by the magnetic field and the surrounding media. The plasma ejection suggests the transport of prominence material into the upper layer by the KHI in its nonlinear stage.

  7. NRSC, Neutron Resonance Spectrum Calculation System

    International Nuclear Information System (INIS)

    Leszczynski, Francisco

    2004-01-01

    1 - Description of program or function: The NRSC system is a package of four programs for calculating detailed neutron spectra and related quantities, for homogeneous mixtures of isotopes and cylindrical reactor pin cells, in the energy resonance region, using ENDF/B evaluated nuclear data pre-processed with NJOY or Cullen's codes up to the Doppler Broadening and unresolved resonance level. 2 - Methods: NRSC consists of four programs: GEXSCO, RMET21, ALAMBDA and WLUTIL. GEXSCO prepares the nuclear data from ENDF/B evaluated nuclear data pre-processed with NJOY or Cullen's codes up to the Doppler Broadening or unresolved resonance level for RMET21 input. RMET21 calculates spectra and related quantities for homogeneous mixtures of isotopes and cylindrical reactor pin cells, in the energy resonance region, using slowing-down algorithms and, in the case of pin cells, the collision probability method. ALAMBDA obtains lambda factors (Goldstein-Cohen intermediate resonance factors in the formalism of WIMSD code) of different isotopes for including on WIMSD-type multigroup libraries for WIMSD or other cell-codes, from output of RMET21 program. WLUTIL is an auxiliary program for extracting tabulated parameters related with RMET21 program calculations from WIMSD libraries for comparisons, and for producing new WIMSD libraries with parameters calculated with RMET21 and ALAMBDA programs. 3 - Restrictions on the complexity of the problem: GEXSCO program has fixed array dimensions that are suitable for processing all reasonable outputs from nuclear data pre-processing programs. RMET21 program uses variable dimension method from a fixed general array. ALAMBDA and WLUTIL programs have fixed arrays that are adapted to standard WIMSD libraries. All programs can be easily modified to adapt to special requirements

  8. Coherent Population Trapping Resonances in Cs Atomic Vapor Layers of Micrometric Thickness

    Directory of Open Access Journals (Sweden)

    A. Krasteva

    2011-01-01

    Full Text Available We report on a novel behavior of the electromagnetically induced absorption (EIA resonance observed on the D2 line of Cs for atoms confined in cells with micrometric thickness. With the enhancement of light intensity, the EIA resonance amplitude suffers from fast reduction, and even at very low intensity (W < 1 mW/cm2, resonance sign reversal takes place and electromagnetically induced transparency (EIT resonance is observed. Similar EIA resonance transformation to EIT one is not observed in conventional cm-size cells. A theoretical model is proposed to analyze the physical processes behind the EIA resonance sign reversal with light intensity. The model involves elastic interactions between Cs atoms as well as elastic interaction of atom micrometric-cell windows, both resulting in depolarization of excited state which can lead to the new observations. The effect of excited state depolarization is confirmed also by the fluorescence (absorption spectra measurement in micrometric cells with different thicknesses.

  9. Cluster observations of reconnection due to the Kelvin-Helmholtz instability at the dawnside magnetospheric flank

    Directory of Open Access Journals (Sweden)

    K. Nykyri

    2006-10-01

    Full Text Available On 3 July 2001, the four Cluster satellites traversed along the dawnside magnetospheric flank and observed large variations in all plasma parameters. The estimated magnetopause boundary normals were oscillating in the z-direction and the normal component of the magnetic field showed systematic  2–3 min bipolar variations for 1 h when the IMF had a small positive bz-component and a Parker-spiral orientation in the x,y-plane. Brief  33 s intervals with excellent deHoffman Teller frames were observed satisfying the Walén relation. Detailed comparisons with 2-D MHD simulations indicate that Cluster encountered rotational discontinuities generated by Kelvin-Helmholtz instability. We estimate a wave length of  6 RE and a wave vector with a significant z-component.

  10. Progress toward Kelvin-Helmholtz instabilities in a High-Energy-Density Plasma on the Nike laser

    Science.gov (United States)

    Harding, E. C.; Drake, R. P.; Gillespie, R. S.; Grosskopf, M. J.; Huntington, C. M.; Aglitskiy, Y.; Weaver, J. L.; Velikovich, A. L.; Plewa, T.; Dwarkadas, V. V.

    2008-04-01

    In the realm of high-energy-density (HED) plasmas, there exist three primary hydrodynamic instabilities of concern: Rayleigh-Taylor (RT), Richtmyer-Meshkov (RM), and Kelvin-Helmholtz (KH). Although the RT and the RM instabilities have been readily observed and diagnosed in the laboratory, the KH instability remains relatively unexplored in HED plasmas. Unlike the RT and RM instabilities, the KH instability is driven by a lifting force generated by a strong velocity gradient in a stratified fluid. Understanding the KH instability mechanism in HED plasmas will provide essential insight into oblique shock systems, jets, mass stripping, and detailed RT-spike development. In addition, our KH experiment will help provide the groundwork for future transition to turbulence experiments. We present 2D FLASH simulations and experimental data from our initial attempts to create a pure KH system using the Nike laser at the Naval Research Laboratory.

  11. Resonant halide perovskite nanoparticles

    Science.gov (United States)

    Tiguntseva, Ekaterina Y.; Ishteev, Arthur R.; Komissarenko, Filipp E.; Zuev, Dmitry A.; Ushakova, Elena V.; Milichko, Valentin A.; Nesterov-Mueller, Alexander; Makarov, Sergey V.; Zakhidov, Anvar A.

    2017-09-01

    The hybrid halide perovskites is a prospective material for fabrication of cost-effective optical devices. Unique perovskites properties are used for solar cells and different photonic applications. Recently, perovskite-based nanophotonics has emerged. Here, we consider perovskite like a high-refractive index dielectric material, which can be considered to be a basis for nanoparticles fabrication with Mie resonances. As a result, we fabricate and study resonant perovskite nanoparticles with different sizes. We reveal, that spherical nanoparticles show enhanced photoluminescence signal. The achieved results lay a cornerstone in the field of novel types of organic-inorganic nanophotonics devices with optical properties improved by Mie resonances.

  12. Behaviour of adipose-derived canine mesenchymal stem cells after superparamagnetic iron oxide nanoparticles labelling for magnetic resonance imaging

    OpenAIRE

    Kolecka, Malgorzata Anna; Arnhold, Stefan; Schmidt, Martin; Reich, Christine; Kramer, Martin; Failing, Klaus; von P?ckler, Kerstin

    2017-01-01

    Background: Therapy with mesenchymal stem cells (MSCs) has been reported to provide beneficial effects in the treatment of neurological and orthopaedic disorders in dogs. The exact mechanism of action is poorly understood. Magnetic resonance imaging (MRI) gives the opportunity to observe MSCs after clinical administration. To visualise MSCs with the help of MRI, labelling with an MRI contrast agent is necessary. However, it must be clarified whether there is any negative influence on cell fun...

  13. The Tracking Resonance Frequency Method for Photoacoustic Measurements Based on the Phase Response

    Science.gov (United States)

    Suchenek, Mariusz

    2017-04-01

    One of the major issues in the use of the resonant photoacoustic cell is the resonance frequency of the cell. The frequency is not stable, and its changes depend mostly on temperature and gas mixture. This paper presents a new method for tracking resonance frequency, where both the amplitude and phase are calculated from the input samples. The stimulating frequency can be adjusted to the resonance frequency of the cell based on the phase. This method was implemented using a digital measurement system with an analog to digital converter, field programmable gate array (FPGA) and a microcontroller. The resonance frequency was changed by the injection of carbon dioxide into the cell. A theoretical description and experimental results are also presented.

  14. Three-Dimensional Simulation of Ultrasound-Induced Microalgal Cell Disruption.

    Science.gov (United States)

    Wang, M; Yuan, W; Hale, Andy

    2016-03-01

    The three-dimensional distribution (x, y, and z) of ultrasound-induced microalgal cell disruption in a sonochemical reactor was predicted by solving the Helmholtz equation using a three-dimensional acoustic module in the COMSOL Multiphysics software. The simulated local ultrasound pressure at any given location (x, y, and z) was found to correlate with cell disruption of a freshwater alga, Scenedesmus dimorphus, represented by the change of algal cell particle/debris concentration, chlorophyll-a fluorescence density (CAFD), and Nile red stained lipid fluorescence density (LFD), which was also validated by the model reaction of potassium iodide oxidation (the Weissler reaction). Furthermore, the effect of ultrasound power intensity and processing duration on algal cell disruption was examined to address the limitation of the model.

  15. Hepatic involvement of Langerhans cell histiocytosis in children - imaging findings of computed tomography, magnetic resonance imaging and magnetic resonance cholangiopancreatography

    International Nuclear Information System (INIS)

    Shi, Yingyan; Qiao, Zhongwei; Gong, Ying; Yang, Haowei; Li, Guoping; Pa, Mier; Xia, Chunmei

    2014-01-01

    Langerhans cell histiocytosis is a rare disease that occurs mainly in children, and hepatic involvement is generally a poor prognostic factor. To describe CT and MRI findings of hepatic involvement of Langerhans cell histiocytosis in children, especially the abnormal bile duct manifestation on magnetic resonance cholangiopancreatography (MRCP). Thirteen children (seven boys, six girls; mean age 28.9 months) were diagnosed with disseminated Langerhans cell histiocytosis. They underwent CT (n = 5) or MRI (n = 4), or CT and MRI examinations (n = 4) to evaluate the liver involvement. Periportal abnormalities presented as band-like or nodular lesions on CT and MRI in all 13 children. The hepatic parenchymal lesions were found in the peripheral regions of the liver in seven children, including multiple nodules on MRI (n = 6), and cystic-like lesions on CT and MRI (n = 3). In 11 of the 13 children the dilatations of the bile ducts were observed on CT and MRI. Eight of the 13 children underwent MR cholangiopancreatography, which demonstrated stenoses or segmental stenoses with slight dilatation of the central bile ducts, including the common hepatic duct and its first-order branches. The peripheral bile ducts in these children showed segmental dilatations and stenoses. Stenosis of the central bile ducts revealed by MR cholangiopancreatography was the most significant finding of liver involvement in Langerhans cell histiocytosis in children. (orig.)

  16. Hepatic involvement of Langerhans cell histiocytosis in children - imaging findings of computed tomography, magnetic resonance imaging and magnetic resonance cholangiopancreatography

    Energy Technology Data Exchange (ETDEWEB)

    Shi, Yingyan; Qiao, Zhongwei; Gong, Ying; Yang, Haowei; Li, Guoping; Pa, Mier [Children' s Hospital of Fudan University, Department of Radiology, Shanghai (China); Xia, Chunmei [Shanghai Medical College of Fudan University, Physiology and Pathophysiology Department, Shanghai (China)

    2014-06-15

    Langerhans cell histiocytosis is a rare disease that occurs mainly in children, and hepatic involvement is generally a poor prognostic factor. To describe CT and MRI findings of hepatic involvement of Langerhans cell histiocytosis in children, especially the abnormal bile duct manifestation on magnetic resonance cholangiopancreatography (MRCP). Thirteen children (seven boys, six girls; mean age 28.9 months) were diagnosed with disseminated Langerhans cell histiocytosis. They underwent CT (n = 5) or MRI (n = 4), or CT and MRI examinations (n = 4) to evaluate the liver involvement. Periportal abnormalities presented as band-like or nodular lesions on CT and MRI in all 13 children. The hepatic parenchymal lesions were found in the peripheral regions of the liver in seven children, including multiple nodules on MRI (n = 6), and cystic-like lesions on CT and MRI (n = 3). In 11 of the 13 children the dilatations of the bile ducts were observed on CT and MRI. Eight of the 13 children underwent MR cholangiopancreatography, which demonstrated stenoses or segmental stenoses with slight dilatation of the central bile ducts, including the common hepatic duct and its first-order branches. The peripheral bile ducts in these children showed segmental dilatations and stenoses. Stenosis of the central bile ducts revealed by MR cholangiopancreatography was the most significant finding of liver involvement in Langerhans cell histiocytosis in children. (orig.)

  17. Surface plasma resonance enhanced photocurrent generation in NiO photoanode based solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Zhong; Cui, Jin [Michael Grätzel Center for Mesoscopic Solar Cells, Wuhan National Laboratory for Optoelectronics Department, Huazhong University of Science and Technology, 1037 Luoyu Road, Wuhan 430074, Hubei (China); Li, Junpeng [State Key Laboratory of Advanced Technologies for Comprehensive Utilization of Platinum Metals, Kunming Institute of Precious Metals, Kunming 650106 (China); Cao, Kun; Yuan, Shuai [Michael Grätzel Center for Mesoscopic Solar Cells, Wuhan National Laboratory for Optoelectronics Department, Huazhong University of Science and Technology, 1037 Luoyu Road, Wuhan 430074, Hubei (China); Cheng, Yibing [Michael Grätzel Center for Mesoscopic Solar Cells, Wuhan National Laboratory for Optoelectronics Department, Huazhong University of Science and Technology, 1037 Luoyu Road, Wuhan 430074, Hubei (China); Department of Materials Engineering, Monash University, Melbourne, Victoria 3800 (Australia); Wang, Mingkui, E-mail: mingkui.wang@mail.hust.edu.cn [Michael Grätzel Center for Mesoscopic Solar Cells, Wuhan National Laboratory for Optoelectronics Department, Huazhong University of Science and Technology, 1037 Luoyu Road, Wuhan 430074, Hubei (China)

    2015-09-15

    Highlights: • SPR effect from Au-nanostructures was first investigated in NiO-based solar cells. • Enhanced photocurrent generation was observed in p-DSC and perovskite solar cell. • Au-nanorods SPR effect induced charge kinetics were investigated. - Abstract: Surface plasma resonance (SPR) effect has been demonstrated to improve solar cell performance. This work reports on the SPR effect from Au nanorod@SiO{sub 2} on p-type dye-sensitized solar cells. Au nanorod@SiO{sub 2} works as an antenna to transform photons with long wavelength into electric field followed by an enhanced excitation of dye. The devices using the NiO electrode containing Au nanorod@SiO{sub 2} shows overall power conversion efficiencies of about 0.2% in combination with I{sup −}/I{sub 3}{sup −} electrolyte, and 0.29% with T{sup −}/T{sub 2} electrolyte, which are superior to those without adding Au nanorods. Detailed investigation including spectroscopy and transient photovoltage decay measurements reveals that plasma effect of Au nanorod@SiO{sub 2} contribute to charge injection efficiency, and thus on the photocurrent. The effect of Au NRs can be further extended to the inverted planar perovskite solar cells, showing obviously improvement in photocurrent.

  18. Resonant Soft X-ray Scattering of Cellulose Microstructure in Plant Primary Cell Walls

    Science.gov (United States)

    Ye, Dan; Kiemle, Sarah N.; Wang, Cheng; Cosgrove, Daniel J.; Gomez, Esther W.; Gomez, Enrique D.

    Cellulosic biomass is the most abundant raw material available for the production of renewable and sustainable biofuels. Breaking down cellulose is the rate-limiting step in economical biofuel production; therefore, a detailed understanding of the microscopic structure of plant cell walls is required to develop efficient biofuel conversion methods. Primary cell walls are key determinants of plant growth and mechanics. Their structure is complex and heterogeneous, making it difficult to elucidate how various components such as pectin, hemicellulose, and cellulose contribute to the overall structure. The electron density of these wall components is similar; such that conventional hard X-ray scattering does not generate enough contrast to resolve the different elements of the polysaccharide network. The chemical specificity of resonant soft X-ray scattering allows contrast to be generated based on differences in chemistry of the different polysaccharides. By varying incident X-ray energies, we have achieved increased scattering contrast between cellulose and other polysaccharides from primary cell walls of onions. By performing scattering at certain energies, features of the network structure of the cell wall are resolved. From the soft X-ray scattering results, we obtained the packing distance of cellulose microfibrils embedded in the polysaccharide network.

  19. Immuno-biosensor for Detection of CD20-Positive Cells Using Surface Plasmon Resonance

    Science.gov (United States)

    Shanehbandi, Dariush; Majidi, Jafar; Kazemi, Tohid; Baradaran, Behzad; Aghebati-Maleki, Leili; Fathi, Farzaneh; Ezzati Nazhad Dolatabadi, Jafar

    2017-01-01

    Purpose: Surface plasmon resonance (SPR) sensing confers a real-time assessment of molecular interactions between biomolecules and their ligands. This approach is highly sensitive and reproducible and could be employed to confirm the successful binding of drugs to cell surface targets. The specific affinity of monoclonal antibodies (MAb) for their target antigens is being utilized for development of immuno-sensors and therapeutic agents. CD20 is a surface protein of B lymphocytes which has been widely employed for immuno-targeting of B-cell related disorders. In the present study, binding ability of an anti-CD20 MAb to surface antigens of intact target cells was investigated by SPR technique. Methods: Two distinct strategies were used for immobilization of the anti-CD20 MAb onto gold (Au) chips. MUA (11-mercaptoundecanoic acid) and Staphylococcus aureus protein A (SpA) were the two systems used for this purpose. A suspension of CD20-positive Raji cells was injected in the analyte phase and the resulting interactions were analyzed and compared to those of MOLT-4 cell line as CD20-negative control. Results: Efficient binding of anti-CD20 MAb to the surface antigens of Raji cell line was confirmed by both immobilizing methods, whereas this MAb had not a noticeable affinity to the MOLT-4 cells. Conclusion: According to the outcomes, the investigated MAb had acceptable affinity and specificity to the target antigens on the cell surface and could be utilized for immuno-detection of CD20-positive intact cells by SPR method. PMID:28761820

  20. Conformally integrated stent cell resonators for wireless monitoring of peripheral artery disease

    KAUST Repository

    Viswanath, Anupam

    2013-01-01

    This paper presents the design and in vitro evaluation of magnetoelastic sensors intended for wireless monitoring of tissue accumulation in peripheral artery stents. The sensors, shaped like stent cells, are fabricated from 28-μm thick foils of magnetoelastic Ni-Fe alloy and are conformally integrated with the stent. The typical sensitivity to viscosity is 427 ppm/cP over a 1.1-8.6 cP range. The sensitivity to mass loading is typically 63,000-65000 ppm/mg with resonant frequency showing an 8.1% reduction for an applied mass that is 15% of the unloaded mass of the sensor. © 2013 IEEE.

  1. Single-resonance optical pumping spectroscopy and application in dressed-state measurement with atomic vapor cell at room temperature.

    Science.gov (United States)

    Liang, Qiangbing; Yang, Baodong; Zhang, Tiancai; Wang, Junmin

    2010-06-21

    By monitoring the transmission of probe laser beam (also served as coupling laser beam) which is locked to a cycling hyperfine transition of cesium D(2) line, while pumping laser is scanned across cesium D(1) or D(2) lines, the single-resonance optical pumping (SROP) spectra are obtained with atomic vapor cell. The SROP spectra indicate the variation of the zero-velocity atoms population of one hyperfine fold of ground state, which is optically pumped into another hyperfine fold of ground state by pumping laser. With the virtue of Doppler-free linewidth, high signal-to-noise ratio (SNR), flat background and elimination of crossover resonance lines (CRLs), the SROP spectra with atomic vapor cell around room temperature can be employed to measure dressed-state splitting of ground state, which is normally detected with laser-cooled atomic sample only, even if the dressed-state splitting is much smaller than the Doppler-broaden linewidth at room temperature.

  2. High Resolution AFM and Single-Cell Resonance Raman Spectroscopy of Geobacter sulfurreducens Biofilms Early in Growth

    Energy Technology Data Exchange (ETDEWEB)

    Lebedev, Nikolai, E-mail: nikolai.lebedev@nrl.navy.mil; Strycharz-Glaven, Sarah M.; Tender, Leonard M., E-mail: nikolai.lebedev@nrl.navy.mil [Center for Biomolecular Science and Engineering, US Naval Research Laboratory, Washington, DC (United States)

    2014-08-21

    Atomic force microscopy and confocal resonance Raman microscopy (CRRM) of single-cells were used to study the transition of anode-grown Geobacter sulfurreducens biofilms from lag phase (initial period of low current) to exponential phase (subsequent period of rapidly increasing current). Results reveal that lag phase biofilms consist of lone cells and tightly packed single-cell thick clusters crisscrossed with extracellular linear structures that appears to be comprised of nodules approximately 20 nm in diameter aligned end to end. By early exponential phase, cell clusters expand laterally and a second layer of closely packed cells begins to form on top of the first. Abundance of c-type cytochromes (c-Cyt) is threefold greater in two-cell thick regions than in one-cell thick regions. The results indicate that early biofilm growth involves two transformations. The first is from lone cells to two-dimensionally associated cells during lag phase when current remains low. This is accompanied by formation of extracellular linear structures. The second is from two- to three-dimensionally associated cells during early exponential phase when current begins to increase rapidly. This is accompanied by a dramatic increase in c-Cyt abundance.

  3. High Resolution AFM and Single-Cell Resonance Raman Spectroscopy of Geobacter sulfurreducens Biofilms Early in Growth

    International Nuclear Information System (INIS)

    Lebedev, Nikolai; Strycharz-Glaven, Sarah M.; Tender, Leonard M.

    2014-01-01

    Atomic force microscopy and confocal resonance Raman microscopy (CRRM) of single-cells were used to study the transition of anode-grown Geobacter sulfurreducens biofilms from lag phase (initial period of low current) to exponential phase (subsequent period of rapidly increasing current). Results reveal that lag phase biofilms consist of lone cells and tightly packed single-cell thick clusters crisscrossed with extracellular linear structures that appears to be comprised of nodules approximately 20 nm in diameter aligned end to end. By early exponential phase, cell clusters expand laterally and a second layer of closely packed cells begins to form on top of the first. Abundance of c-type cytochromes (c-Cyt) is threefold greater in two-cell thick regions than in one-cell thick regions. The results indicate that early biofilm growth involves two transformations. The first is from lone cells to two-dimensionally associated cells during lag phase when current remains low. This is accompanied by formation of extracellular linear structures. The second is from two- to three-dimensionally associated cells during early exponential phase when current begins to increase rapidly. This is accompanied by a dramatic increase in c-Cyt abundance.

  4. Understanding Kelvin-Helmholtz instability in paraffin-based hybrid rocket fuels

    Science.gov (United States)

    Petrarolo, Anna; Kobald, Mario; Schlechtriem, Stefan

    2018-04-01

    Liquefying fuels show higher regression rates than the classical polymeric ones. They are able to form, along their burning surface, a low viscosity and surface tension liquid layer, which can become unstable (Kelvin-Helmholtz instability) due to the high velocity gas flow in the fuel port. This causes entrainment of liquid droplets from the fuel surface into the oxidizer gas flow. To better understand the droplets entrainment mechanism, optical investigations on the combustion behaviour of paraffin-based hybrid rocket fuels in combination with gaseous oxygen have been conducted in the framework of this research. Combustion tests were performed in a 2D single-slab burner at atmospheric conditions. High speed videos were recorded and analysed with two decomposition techniques. Proper orthogonal decomposition (POD) and independent component analysis (ICA) were applied to the scalar field of the flame luminosity. The most excited frequencies and wavelengths of the wave-like structures characterizing the liquid melt layer were computed. The fuel slab viscosity and the oxidizer mass flow were varied to study their influence on the liquid layer instability process. The combustion is dominated by periodic, wave-like structures for all the analysed fuels. Frequencies and wavelengths characterizing the liquid melt layer depend on the fuel viscosity and oxidizer mass flow. Moreover, for very low mass flows, no wavelength peaks are detected for the higher viscosity fuels. This is important to better understand and predict the onset and development of the entrainment process, which is connected to the amplification of the longitudinal waves.

  5. Spatial distribution of rolled up Kelvin-Helmholtz vortices at Earth's dayside and flank magnetopause

    Directory of Open Access Journals (Sweden)

    M. G. G. T. Taylor

    2012-06-01

    Full Text Available The Kelvin-Helmholtz Instability (KHI can drive waves at the magnetopause. These waves can grow to form rolled-up vortices and facilitate transfer of plasma into the magnetosphere. To investigate the persistence and frequency of such waves at the magnetopause we have carried out a survey of all Double Star 1 magnetopause crossings, using a combination of ion and magnetic field measurements. Using criteria originally used in a Geotail study made by Hasegawa et al. (2006 (forthwith referred to as H2006, 17 candidate events were identified from the entire TC-1 mission (covering ~623 orbits where the magnetopause was sampled, a majority of which were on the dayside of the terminator. The relationship between density and shear velocity was then investigated, to identify the predicted signature of a rolled up vortex from H2006 and all 17 events exhibited some level of rolled up behavior. The location of the events had a clear dawn-dusk asymmetry, with 12 (71% on the post noon, dusk flank suggesting preferential growth in this region.

  6. Giant cell tumor of the tendon sheath of the hand - magnetic resonance image and orthopaedic treatment

    International Nuclear Information System (INIS)

    Kirova, G.; Monovska, T.; Jablanski, V.; Alexieva, K.; Velev, M.

    2009-01-01

    Giant cell tumour of the tendon sheath (GCT-TS), also known as localized nodular tenosynovitis, is a benign neoplasm that occurs dominantly on the digits. These tumours most commonly occur in patients aged 30-50 years and are associated with degenerative joint disease. GCT-TS usually arises from the synovium of tendon sheets, affecting interfalangeal joints of the hand, feet, ankle and knees. Magnetic Resonance Imaging is able to depict characteristic signal intensities and can accurately assess the tumor size and degree of extent around the phalanx. We present a case of a 36 years-old male patient with GCT-TS in the flexor tendon of his left second finger, diagnosed with Magnetic Resonance imaging. The mass was excised widely with preservation of the flexor tendon without recurrence. (authors)

  7. Magnetic resonance angiography of the extracranial carotid and vertebral arteries

    International Nuclear Information System (INIS)

    Akimura, Tatsuo; Saito, Kenichi; Nakayama, Hisato; Kashiwagi, Shiro; Kato, Shoichi; Ito, Haruhide.

    1994-01-01

    To evaluate the contribution of magnetic resonance angiography (MRA) in the screening study of the extracranial carotid and vertebral arteries using the conventional head and neck coils, 500 consecutive MRAs of the cervical vessels were performed using 1.5 tesla magnetic resonance unit with circularly polarized head coil. The 5 cm-thick imaging plane was placed in coronal fashion including both carotid and vertebral arteries. The imaging sequence was three-dimensional (3D) fast imaging with steady precession (FISP). In 10 patients with failed head coil examination, 10 patients with possible carotid and vertebral diseases and 10 volunteers, the extracranial carotid and vertebral arteries were examined with the Helmholtz neck coil. Both 3D- and 2D-FISP were performed in each case. The imaging plane was placed in oblique sagittal fashion. In 458 out of 500 cases (91.6%), the extracranial carotid and vertebral arteries were successfully depicted using head coil. In 20 patients with high shoulders, the carotid bifurcations were out of range of the head coil. In these cases, carotid bifurcations and the origins of the carotid and vertebral arteries were successfully revealed using a neck coil. To evaluate the stenotic lesions and tortuous vessels, 2D-FISP sequence seemed to be more suitable than 3D-FISP. Compared with conventional angiography, MRA caused overestimation of the degree of stenotic lesions. For screening examination of the extracranial carotid and vertebral arteries, most cases can be evaluated only with the conventional head coil. If depiction of the carotid bifurcation fails and the examination of carotids or vertebrals down to the aortic arch is needed, neck coil examination is required. (author)

  8. A new chapter in doctoral candidate training: The Helmholtz Space Life Sciences Research School (SpaceLife)

    Science.gov (United States)

    Hellweg, C. E.; Gerzer, R.; Reitz, G.

    2011-05-01

    In the field of space life sciences, the demand of an interdisciplinary and specific training of young researchers is high due to the complex interaction of medical, biological, physical, technical and other questions. The Helmholtz Space Life Sciences Research School (SpaceLife) offers an excellent interdisciplinary training for doctoral students from different fields (biology, biochemistry, biotechnology, physics, psychology, nutrition or sports sciences and related fields) and any country. SpaceLife is coordinated by the Institute of Aerospace Medicine at the German Aerospace Center (DLR) in Cologne. The German Universities in Kiel, Bonn, Aachen, Regensburg, Magdeburg and Berlin, and the German Sports University (DSHS) in Cologne are members of SpaceLife. The Universities of Erlangen-Nürnberg, Frankfurt, Hohenheim, and the Beihang University in Beijing are associated partners. In each generation, up to 25 students can participate in the three-year program. Students learn to develop integrated concepts to solve health issues in human spaceflight and in related disease patterns on Earth, and to further explore the requirements for life in extreme environments, enabling a better understanding of the ecosystem Earth and the search for life on other planets in unmanned and manned missions. The doctoral candidates are coached by two specialist supervisors from DLR and the partner university, and a mentor. All students attend lectures in different subfields of space life sciences to attain an overview of the field: radiation and gravitational biology, astrobiology and space physiology, including psychological aspects of short and long term space missions. Seminars, advanced lectures, laboratory courses and stays at labs at the partner institutions or abroad are offered as elective course and will provide in-depth knowledge of the chosen subfield or allow to appropriate innovative methods. In Journal Clubs of the participating working groups, doctoral students learn

  9. A new relativistic viscous hydrodynamics code and its application to the Kelvin-Helmholtz instability in high-energy heavy-ion collisions

    Energy Technology Data Exchange (ETDEWEB)

    Okamoto, Kazuhisa [Nagoya University, Department of Physics, Nagoya (Japan); Nonaka, Chiho [Nagoya University, Department of Physics, Nagoya (Japan); Nagoya University, Kobayashi-Maskawa Institute for the Origin of Particles and the Universe (KMI), Nagoya (Japan); Duke University, Department of Physics, Durham, NC (United States)

    2017-06-15

    We construct a new relativistic viscous hydrodynamics code optimized in the Milne coordinates. We split the conservation equations into an ideal part and a viscous part, using the Strang spitting method. In the code a Riemann solver based on the two-shock approximation is utilized for the ideal part and the Piecewise Exact Solution (PES) method is applied for the viscous part. We check the validity of our numerical calculations by comparing analytical solutions, the viscous Bjorken's flow and the Israel-Stewart theory in Gubser flow regime. Using the code, we discuss possible development of the Kelvin-Helmholtz instability in high-energy heavy-ion collisions. (orig.)

  10. A new relativistic viscous hydrodynamics code and its application to the Kelvin-Helmholtz instability in high-energy heavy-ion collisions

    Science.gov (United States)

    Okamoto, Kazuhisa; Nonaka, Chiho

    2017-06-01

    We construct a new relativistic viscous hydrodynamics code optimized in the Milne coordinates. We split the conservation equations into an ideal part and a viscous part, using the Strang spitting method. In the code a Riemann solver based on the two-shock approximation is utilized for the ideal part and the Piecewise Exact Solution (PES) method is applied for the viscous part. We check the validity of our numerical calculations by comparing analytical solutions, the viscous Bjorken's flow and the Israel-Stewart theory in Gubser flow regime. Using the code, we discuss possible development of the Kelvin-Helmholtz instability in high-energy heavy-ion collisions.

  11. Studies of magnetic resonance in anemia of hematies falciformes

    International Nuclear Information System (INIS)

    Lores Guevara, Manuel Arsenio; Balcom, Bruce John; Cabal Mirabal, Carlos

    2012-01-01

    Magnetic Resonance applications to the study of Sickle Cell Disease are analyzed using classical procedures and Unilateral Magnetic Resonance. Hemoglobin and whole blood samples were obtained from healthy individual and patients with Sickle Cell Anemia to be used as samples. Classical pulse sequence as spin echo and inversion recovery were used in the experimental studies, the STEPR method was used for EPR spectrometric determinations. The results show the possibility of NMR methods to follow the molecular process causing the disease and allows to present quantitative procedures to estimate the clinical state of the patients and the results of clinical options. We present the Unilateral Magnetic Resonance as a new method to study Sickle Cell disease considering its portability and new possibilities as new image method

  12. Performance Improvement of Polymer Solar Cells by Surface-Energy-Induced Dual Plasmon Resonance.

    Science.gov (United States)

    Yao, Mengnan; Shen, Ping; Liu, Yan; Chen, Boyuan; Guo, Wenbin; Ruan, Shengping; Shen, Liang

    2016-03-09

    The surface plasmon resonance (SPR) effect of metal nanoparticles (MNPs) is effectively applied on polymer solar cells (PSCs) to improve power conversion efficiency (PCE). However, universality of the reported results mainly focused on utilizing single type of MNPs to enhance light absorption only in specific narrow wavelength range. Herein, a surface-energy-induced dual MNP plasmon resonance by thermally evaporating method was presented to achieve the absorption enhancement in wider range. The differences of surface energy between silver (Ag), gold (Au), and tungsten trioxide (WO3) compared by contact angle images enable Ag and Au prefer to respectively aggregate into isolated islands rather than films at the initial stage of the evaporation process, which was clearly demonstrated in the atomic force microscopy (AFM) measurement. The sum of plasmon-enhanced wavelength range induced by both Ag NPs (350-450 nm) and Au NPs (450-600 nm) almost cover the whole absorption spectra of active layers, which compatibly contribute a significant efficiency improvement from 4.57 ± 0.16 to 6.55 ± 0.12% compared to the one without MNPs. Besides, steady state photoluminescence (PL) measurements provide strong evidence that the SPR induced by the Ag-Au NPs increase the intensity of light absorption. Finally, ultraviolet photoelectron spectroscopy (UPS) reveals that doping Au and Ag causes upper shift of both the work function and valence band of WO3, which is directly related to hole collection ability. We believe the surface-energy-induced dual plasmon resonance enhancement by simple thermally evaporating technique might pave the way toward higher-efficiency PSCs.

  13. The long-term fate of mesenchymal stem cells labeled with magnetic resonance imaging-visible polymersomes in cerebral ischemia

    Directory of Open Access Journals (Sweden)

    Duan X

    2017-09-01

    Full Text Available Xiaohui Duan,1,* Liejing Lu,1,* Yong Wang,2 Fang Zhang,1 Jiaji Mao,1 Minghui Cao,1 Bingling Lin,1 Xiang Zhang,1 Xintao Shuai,2,3 Jun Shen1 1Department of Radiology, Sun Yat-Sen Memorial Hospital, 2PCFM Lab of Ministry of Education, School of Materials Science and Engineering, 3BME Center, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, People’s Republic of China *These authors contributed equally to this work Abstract: Understanding the long-term fate and potential mechanisms of mesenchymal stem cells (MSCs after transplantation is essential for improving functional benefits of stem cell-based stroke treatment. Magnetic resonance imaging (MRI is considered an attractive and clinically translatable tool for longitudinal tracking of stem cells, but certain controversies have arisen in this regard. In this study, we used SPION-loaded cationic polymersomes to label green fluorescent protein (GFP-expressing MSCs to determine whether MRI can accurately reflect survival, long-term fate, and potential mechanisms of MSCs in ischemic stroke therapy. Our results showed that MSCs could improve the functional outcome and reduce the infarct volume of stroke in the brain. In vivo MRI can verify the biodistribution and migration of grafted cells when pre-labeled with SPION-loaded polymersome. The dynamic change of low signal volume on MRI can reflect the tendency of cell survival and apoptosis, but may overestimate long-term survival owing to the presence of iron-laden macrophages around cell graft. Only a small fraction of grafted cells survived up to 8 weeks after transplantation. A minority of these surviving cells were differentiated into astrocytes, but not into neurons. MSCs might exert their therapeutic effect via secreting paracrine factors rather than directing cell replacement through differentiation into neuronal and/or glial phenotypes. Keywords: mesenchymal stem cells, magnetic resonance imaging, superparamagnetic iron oxide

  14. Granular Cell Tumor of the Neurohypophysis: A Case Report with Magnetic Resonance and CT Imaging Findings

    Energy Technology Data Exchange (ETDEWEB)

    Choo, Ka Yeon; Lee, Sun Jin; Ahn, Kook Jin; Jung, So Lyung; Kim, Bum Soo [Dept. of Radiology, Seoul St.Mary' s Hospital, The Catholic University of Korea College of Medicine, Seoul (Korea, Republic of); Lee, Yeon Soo [Dept. of Pathology, Seoul St.Mary' s Hospital, The Catholic University of Korea College of Medicine, Seoul (Korea, Republic of); Jeun, Shin Soo [Dept. of Neurosurgery, Seoul St.Mary' s Hospital, The Catholic University of Korea College of Medicine, Seoul (Korea, Republic of)

    2011-11-15

    A granular cell tumor (GCT) usually occurs as a small, solitary, nodular tumor and is more prevalent in adult females. The authors report the magnetic resonance (MR) and CT imaging findings in a 61-year-old woman with GCT of the neurohypophysis presenting with a history of reduced visual acuity in her right eye. MR images showed a suprasellar mass with an isointense signal on a T1-weighted image and an hypointense signal on a T2-weighted image. The histopathological examination revealed a granular cell tumor. In this article, the MR and CT imaging findings of GCT of the neurohypophysis with the literature reviews are discussed.

  15. Granular Cell Tumor of the Neurohypophysis: A Case Report with Magnetic Resonance and CT Imaging Findings

    International Nuclear Information System (INIS)

    Choo, Ka Yeon; Lee, Sun Jin; Ahn, Kook Jin; Jung, So Lyung; Kim, Bum Soo; Lee, Yeon Soo; Jeun, Shin Soo

    2011-01-01

    A granular cell tumor (GCT) usually occurs as a small, solitary, nodular tumor and is more prevalent in adult females. The authors report the magnetic resonance (MR) and CT imaging findings in a 61-year-old woman with GCT of the neurohypophysis presenting with a history of reduced visual acuity in her right eye. MR images showed a suprasellar mass with an isointense signal on a T1-weighted image and an hypointense signal on a T2-weighted image. The histopathological examination revealed a granular cell tumor. In this article, the MR and CT imaging findings of GCT of the neurohypophysis with the literature reviews are discussed.

  16. Förster resonance energy transfer demonstrates a flavonoid metabolon in living plant cells that displays competitive interactions between enzymes

    NARCIS (Netherlands)

    Crosby, K.C.; Pietraszewska-Bogiel, A.; Gadella (jr.), T.W.J.; Winkel, B.S.J.

    2011-01-01

    We have used Förster resonance energy transfer detected by fluorescence lifetime imaging microscopy (FLIM-FRET) to provide the first evidence from living plants cells for the existence of a flavonoid metabolon. The distribution of flux within this system may be regulated by the direct competition of

  17. Journal of EEA, Vol. 28, 2011 PERFORMANCE EVALUATION OF A ...

    African Journals Online (AJOL)

    Zede

    should not be hampered by the back pressure ... internal combustion engines, the engine exhaust ... pipe. Reactive silencer design is based either on the principle of a Helmholtz resonator ..... outlet, the velocity of exhaust gas is increased due.

  18. Complementary Split Ring Resonator Based Triple Band Microstrip Antenna for WLAN/WiMAX Applications

    Directory of Open Access Journals (Sweden)

    W. Ali

    2017-04-01

    Full Text Available A new simple design of a triple-band microstrip antenna using metamaterial concept is presented in this paper. Multi-unit cell was the key of the multi resonance response that was obtained by etching two circular and one rectangular split ring resonator (SRR unit cells in the ground plane of a conventional patch operating at 3.56 GHz .The circular unit cells are resonating at 5.6 GHz for the upper band of Wi-MAX, while the rectangular cell is designed to produce a resonance at 2.45 GHz for the lower band of WLAN. WiMAX's/WLAN's operating bands are covered by the triple resonances which are achieved by the proposed antenna with quite enhanced performance. A detailed parametric study of the placement for the metamaterial unit cells is introduced and the most suitable positions are chosen to be the place of the unit cells for enhanced performance. A good consistency between simulation and measurement confirms the ability of the proposed antenna to achieve an improved gain at the three different frequencies.

  19. Development of cell-based quantitative evaluation method for cell cycle-arrest type cancer drugs for apoptosis by high precision surface plasmon resonance sensor

    Science.gov (United States)

    Ona, Toshihiro; Nishijima, Hiroshi; Kosaihira, Atsushi; Shibata, Junko

    2008-04-01

    In vitro rapid and quantitative cell-based assay is demanded to verify the efficacy prediction of cancer drugs since a cancer patient may have unconventional aspects of tumor development. Here, we show the rapid and non-label quantitative verifying method and instrumentation of apoptosis for cell cycle-arrest type cancer drugs (Roscovitine and D-allose) by reaction analysis of living liver cancer cells cultured on a sensor chip with a newly developed high precision (50 ndeg s -1 average fluctuation) surface plasmon resonance (SPR) sensor. The time-course cell reaction as the SPR angle change rate for 10 min from 30 min cell culture with a drug was significantly related to cell viability. By the simultaneous detection of differential SPR angle change and fluorescence by specific probes using the new instrument, the SPR angle was related to the nano-order potential decrease in inner mitochondrial membrane potential. The results obtained are universally valid for the cell cycle-arrest type cancer drugs, which mediate apoptosis through different cell-signaling pathways, by a liver cancer cell line of Hep G2 (P<0.001). This system towards the application to evaluate personal therapeutic potentials of drugs using cancer cells from patients in clinical use.

  20. High resolution in-operando microimaging of solar cells with pulsed electrically-detected magnetic resonance

    Science.gov (United States)

    Katz, Itai; Fehr, Matthias; Schnegg, Alexander; Lips, Klaus; Blank, Aharon

    2015-02-01

    The in-operando detection and high resolution spatial imaging of paramagnetic defects, impurities, and states becomes increasingly important for understanding loss mechanisms in solid-state electronic devices. Electron spin resonance (ESR), commonly employed for observing these species, cannot meet this challenge since it suffers from limited sensitivity and spatial resolution. An alternative and much more sensitive method, called electrically-detected magnetic resonance (EDMR), detects the species through their magnetic fingerprint, which can be traced in the device's electrical current. However, until now it could not obtain high resolution images in operating electronic devices. In this work, the first spatially-resolved electrically-detected magnetic resonance images (EDMRI) of paramagnetic states in an operating real-world electronic device are provided. The presented method is based on a novel microwave pulse sequence allowing for the coherent electrical detection of spin echoes in combination with powerful pulsed magnetic-field gradients. The applicability of the method is demonstrated on a device-grade 1-μm-thick amorphous silicon (a-Si:H) solar cell and an identical device that was degraded locally by an electron beam. The degraded areas with increased concentrations of paramagnetic defects lead to a local increase in recombination that is mapped by EDMRI with ∼20-μm-scale pixel resolution. The novel approach presented here can be widely used in the nondestructive in-operando three-dimensional characterization of solid-state electronic devices with a resolution potential of less than 100 nm.

  1. Calculation of Energy Band Diagram of a Photoelectrochemical Water Splitting Cell

    OpenAIRE

    Cendula, P.; Tilley, S. D.; Gimenez, S.; Schmid, M.; Bisquert, J.; Graetzel, M.; Schumacher, J. O.

    2014-01-01

    A physical model is presented for a semiconductor electrode of a photoelectrochemical (PEC) cell, accounting for the potential drop in the Helmholtz layer. Hence both band edge pinning and unpinning are naturally included in our description. The model is based on the continuity equations for charge carriers and direct charge transfer from the energy bands to the electrolyte. A quantitative calculation of the position of the energy bands and the variation of the quasi-Fermi levels in the semic...

  2. Organic solar cells: understanding the role of Förster resonance energy transfer.

    Science.gov (United States)

    Feron, Krishna; Belcher, Warwick J; Fell, Christopher J; Dastoor, Paul C

    2012-12-12

    Organic solar cells have the potential to become a low-cost sustainable energy source. Understanding the photoconversion mechanism is key to the design of efficient organic solar cells. In this review, we discuss the processes involved in the photo-electron conversion mechanism, which may be subdivided into exciton harvesting, exciton transport, exciton dissociation, charge transport and extraction stages. In particular, we focus on the role of energy transfer as described by F¨orster resonance energy transfer (FRET) theory in the photoconversion mechanism. FRET plays a major role in exciton transport, harvesting and dissociation. The spectral absorption range of organic solar cells may be extended using sensitizers that efficiently transfer absorbed energy to the photoactive materials. The limitations of F¨orster theory to accurately calculate energy transfer rates are discussed. Energy transfer is the first step of an efficient two-step exciton dissociation process and may also be used to preferentially transport excitons to the heterointerface, where efficient exciton dissociation may occur. However, FRET also competes with charge transfer at the heterointerface turning it in a potential loss mechanism. An energy cascade comprising both energy transfer and charge transfer may aid in separating charges and is briefly discussed. Considering the extent to which the photo-electron conversion efficiency is governed by energy transfer, optimisation of this process offers the prospect of improved organic photovoltaic performance and thus aids in realising the potential of organic solar cells.

  3. Organic Solar Cells: Understanding the Role of Förster Resonance Energy Transfer

    Directory of Open Access Journals (Sweden)

    Paul C. Dastoor

    2012-12-01

    Full Text Available Organic solar cells have the potential to become a low-cost sustainable energy source. Understanding the photoconversion mechanism is key to the design of efficient organic solar cells. In this review, we discuss the processes involved in the photo-electron conversion mechanism, which may be subdivided into exciton harvesting, exciton transport, exciton dissociation, charge transport and extraction stages. In particular, we focus on the role of energy transfer as described by F¨orster resonance energy transfer (FRET theory in the photoconversion mechanism. FRET plays a major role in exciton transport, harvesting and dissociation. The spectral absorption range of organic solar cells may be extended using sensitizers that efficiently transfer absorbed energy to the photoactive materials. The limitations of F¨orster theory to accurately calculate energy transfer rates are discussed. Energy transfer is the first step of an efficient two-step exciton dissociation process and may also be used to preferentially transport excitons to the heterointerface, where efficient exciton dissociation may occur. However, FRET also competes with charge transfer at the heterointerface turning it in a potential loss mechanism. An energy cascade comprising both energy transfer and charge transfer may aid in separating charges and is briefly discussed. Considering the extent to which the photo-electron conversion efficiency is governed by energy transfer, optimisation of this process offers the prospect of improved organic photovoltaic performance and thus aids in realising the potential of organic solar cells.

  4. Helmholtz Natural Modes: the universal and discrete spatial fabric of electromagnetic wavefields

    International Nuclear Information System (INIS)

    El Gawhary, Omar

    2017-01-01

    The interaction of electromagnetic waves with matter is at the foundation of the way we perceive and explore the world around us. In fact, when a field interacts with an object, signatures on the object’s geometry and physical properties are recorded in the resulting scattered field and are transported away from the object, where they can eventually be detected and processed. An optical field can transport information through its spectral content, its polarization state, and its spatial distribution. Generally speaking, the field’s spatial structure is typically subjected to changes under free-space propagation and any information therein encoded gets reshuffled by the propagation process. We must ascribe to this fundamental reason the fact that spectroscopy was known to the ancient civilizations already, and founded as modern science in the middle of seventeenth century, while to date we do not have an established scientific of field of ‘spatial spectroscopy’ yet. In this work we tackle this issue and we show how any field, whose evolution is dictated by Helmholtz equation, contains a universal and invariant spatial structure. When expressed in the framework of this spatial fabric, the spatial information content carried by any field reveals its invariant nature. This opens the way to novel paradigms in optical digital communications, inverse scattering, materials inspection, nanometrology and quantum optics. (paper)

  5. Pulse sequences for contrast-enhanced magnetic resonance imaging

    International Nuclear Information System (INIS)

    Graves, Martin J.

    2007-01-01

    The theory and application of magnetic resonance imaging (MRI) pulse sequences following the administration of an exogenous contrast agent are discussed. Pulse sequences are categorised according to the contrast agent mechanism: changes in proton density, relaxivity, magnetic susceptibility and resonant frequency shift. Applications in morphological imaging, magnetic resonance angiography, dynamic imaging and cell labelling are described. The importance of optimising the pulse sequence for each application is emphasised

  6. Magnetic resonance imaging in the staging of renal cell carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Kishi, Hiroichi; Umeda, Takashi; Niijima, Tadao; Yashiro, Naobumi; Kawabe, Kazuki

    1987-07-01

    Eighteen patients with renal neoplasm underwent magnetic resonance imaging (MRI) using a 1.5 Tesla superconducting magnetic system and spin echo images were obtained by quick scan technique under holding breath. MR images were interpreted independently of the computerized tomography (CT) findings. The preoperative stagings of the 18 renal carcinomas, as judged by MRI, were compared with those obtained at laparotomy. The anatomic staging was correctly performed by MRI in 13 patients (72 %). In the patients who had intrarenal small tumor with normal renal contour, MRI demonstrated a solid mass clearly distinguishable from surrounding renal parenchyma using the paramagnetic contrast agent (gadolinium-DTPA). When compared with results of evaluation by CT in staging, MRI appeared to have several advantages in determination of whole mass; the detection of tumor thrombus into renal vein and inferior vena cava; and the evaluation of direct tumor invasion of adjacent organs. MRI should play an important role in the staging of renal cell carcinoma.

  7. Magnetic resonance imaging in the staging of renal cell carcinoma

    International Nuclear Information System (INIS)

    Kishi, Hiroichi; Umeda, Takashi; Niijima, Tadao; Yashiro, Naobumi; Kawabe, Kazuki

    1987-01-01

    Eighteen patients with renal neoplasm underwent magnetic resonance imaging (MRI) using a 1.5 Tesla superconducting magnetic system and spin echo images were obtained by quick scan technique under holding breath. MR images were interpreted independently of the computerized tomography (CT) findings. The preoperative stagings of the 18 renal carcinomas, as judged by MRI, were compared with those obtained at laparotomy. The anatomic staging was correctly performed by MRI in 13 patients (72 %). In the patients who had intrarenal small tumor with normal renal contour, MRI demonstrated a solid mass clearly distinguishable from surrounding renal parenchyma using the paramagnetic contrast agent (gadolinium-DTPA). When compared with results of evaluation by CT in staging, MRI appeared to have several advantages in determination of whole mass; the detection of tumor thrombus into renal vein and inferior vena cava; and the evaluation of direct tumor invasion of adjacent organs. MRI should play an important role in the staging of renal cell carcinoma. (author)

  8. Voxel-wise prostate cell density prediction using multiparametric magnetic resonance imaging and machine learning.

    Science.gov (United States)

    Sun, Yu; Reynolds, Hayley M; Wraith, Darren; Williams, Scott; Finnegan, Mary E; Mitchell, Catherine; Murphy, Declan; Haworth, Annette

    2018-04-26

    There are currently no methods to estimate cell density in the prostate. This study aimed to develop predictive models to estimate prostate cell density from multiparametric magnetic resonance imaging (mpMRI) data at a voxel level using machine learning techniques. In vivo mpMRI data were collected from 30 patients before radical prostatectomy. Sequences included T2-weighted imaging, diffusion-weighted imaging and dynamic contrast-enhanced imaging. Ground truth cell density maps were computed from histology and co-registered with mpMRI. Feature extraction and selection were performed on mpMRI data. Final models were fitted using three regression algorithms including multivariate adaptive regression spline (MARS), polynomial regression (PR) and generalised additive model (GAM). Model parameters were optimised using leave-one-out cross-validation on the training data and model performance was evaluated on test data using root mean square error (RMSE) measurements. Predictive models to estimate voxel-wise prostate cell density were successfully trained and tested using the three algorithms. The best model (GAM) achieved a RMSE of 1.06 (± 0.06) × 10 3 cells/mm 2 and a relative deviation of 13.3 ± 0.8%. Prostate cell density can be quantitatively estimated non-invasively from mpMRI data using high-quality co-registered data at a voxel level. These cell density predictions could be used for tissue classification, treatment response evaluation and personalised radiotherapy.

  9. Microcanonical-ensemble computer simulation of the high-temperature expansion coefficients of the Helmholtz free energy of a square-well fluid

    Science.gov (United States)

    Sastre, Francisco; Moreno-Hilario, Elizabeth; Sotelo-Serna, Maria Guadalupe; Gil-Villegas, Alejandro

    2018-02-01

    The microcanonical-ensemble computer simulation method (MCE) is used to evaluate the perturbation terms Ai of the Helmholtz free energy of a square-well (SW) fluid. The MCE method offers a very efficient and accurate procedure for the determination of perturbation terms of discrete-potential systems such as the SW fluid and surpass the standard NVT canonical ensemble Monte Carlo method, allowing the calculation of the first six expansion terms. Results are presented for the case of a SW potential with attractive ranges 1.1 ≤ λ ≤ 1.8. Using semi-empirical representation of the MCE values for Ai, we also discuss the accuracy in the determination of the phase diagram of this system.

  10. Design of Transparent Anodes for Resonant Cavity Enhanced Light Harvesting in Organic Solar Cells

    KAUST Repository

    Sergeant, Nicholas P.

    2012-01-03

    The use of an ITO-free MoO 3/Ag/MoO 3 anode to control the photon harvesting in PCDTBT:PC 70BM solar cells is proposed. At first sight, the fact that these anodes possess reduced far-field transmission compared to ITO may seem to be a disadvantage. But, despite this, we show that by carefully tuning the resonant optical cavity we can enhance the external quantum efficiency close to the band edge of PCDTBT, resulting in high photocurrent and power conversion efficiency on par with ITO. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  11. High-pressure nuclear magnetic resonance studies of fuel cell membranes

    Science.gov (United States)

    Mananga, Eugene Stephane

    water at different concentrations: proton (1H) and phosphorus (31P) nuclei have been performed using the static field gradient spin-echo nuclear magnetic resonance. This study is expected to be helpful in improving the understanding of phosphoric acid fuel cell technology.

  12. Description of the resonance treatment in WIMS-AECL

    Energy Technology Data Exchange (ETDEWEB)

    Donnelly, J V

    1993-05-01

    The Stamm`ler resonance treatment as applied within the WIMS-AECL lattice cell code is described. The validation work demonstrating the accuracy of the resonance treatment is reviewed and indicates that the methods used will be accurate for the current range of application within AECL. (author). 22 refs., 6 tabs.

  13. Different energy metabolism in two human small cell lung cancer subpopulations examined by 31P magnetic resonance spectroscopy and biochemical analysis in vivo and in vitro

    DEFF Research Database (Denmark)

    Kristjansen, P E; Spang-Thomsen, M; Quistorff, B

    1991-01-01

    Two human small cell lung cancer tumor lines, maintained as solid tumor xenografts on nude mice and as in vitro cell cultures, were studied by in vivo 31P magnetic resonance spectroscopy and by biochemical analysis of extracts of solid tumors and cell cultures. The tumor lines CPH SCCL 54A and CPH...

  14. Novel Anterior Brainstem Magnetic Resonance Imaging Findings in Non-Small Cell Lung Cancer with Leptomeningeal Carcinomatosis

    Directory of Open Access Journals (Sweden)

    Chun-Yu Cheng

    2017-10-01

    Full Text Available Leptomeningeal carcinomatosis (LC is found in around 4% of patients with non-small cell lung cancer (NSCLC. The most common radiological finding of LC is diffuse leptomeningeal enhancement on contrast-enhanced brain magnetic resonance imaging (MRI. Herein, we report a novel brain MRI finding—non-enhanced, band-like, symmetric restricted diffusion along the anterior surface of the brainstem—of LC in four patients with NSCLC. We also identified three additional cases with similar MRI findings in a literature review. We hypothesized that the restricted diffusion along the anterior brainstem was caused by malignant cells concentrating in the cistern around the brainstem and infiltrating into the circumferential perforating arteries along the anterior brainstem surface, which then resulted in microinfarctions.

  15. Global reconnection topology as inferred from plasma observations inside Kelvin-Helmholtz vortices

    Directory of Open Access Journals (Sweden)

    M. B. Bavassano Cattaneo

    2010-04-01

    Full Text Available During a long lasting period of northward interplanetary magnetic field and high solar wind speed (above 700 km/s, the Cluster spacecraft go across a number of very large rolled-up Kelvin-Helmholtz (KH vortices at the dusk magnetopause, close to the terminator. The peculiarity of the present event is a particular sequence of ions and electrons distribution functions observed repeatedly inside each vortex. In particular, whenever Cluster crosses the current layer inside the vortices, multiple field-aligned ion populations appear, suggesting the occurrence of reconnection. In addition, the ion data display a clear velocity filter effect both at the leading and at the trailing edge of each vortex. This effect is not present in the simultaneous electron data. Unlike other KH studies reported in the literature in which reconnection occurs within the vortices, in the present event the observations are not compatible with local reconnection, but are accounted for by lobe reconnection occurring along an extended X-line at the terminator in the Southern Hemisphere. The reconnected field lines "sink" across the magnetopause and then convect tailward-duskward where they become embedded in the vortices. Another observational evidence is the detected presence of solar wind plasma on the magnetospheric side of the vortices, which confirms unambiguously the occurrence of mass transport across the magnetopause already reported in the literature. The proposed reconnection scenario accounts for all the observational aspects, regarding both the transport process and the kinetic signatures.

  16. ¹⁹F magnetic resonance probes for live-cell detection of peroxynitrite using an oxidative decarbonylation reaction.

    Science.gov (United States)

    Bruemmer, Kevin J; Merrikhihaghi, Sara; Lollar, Christina T; Morris, Siti Nur Sarah; Bauer, Johannes H; Lippert, Alexander R

    2014-10-21

    We report a newly discovered oxidative decarbonylation reaction of isatins that is selectively mediated by peroxynitrite (ONOO(-)) to provide anthranilic acid derivatives. We have harnessed this rapid and selective transformation to develop two reaction-based probes, 5-fluoroisatin and 6-fluoroisatin, for the low-background readout of ONOO(-) using (19)F magnetic resonance spectroscopy. 5-fluoroisatin was used to non-invasively detect ONOO(-) formation in living lung epithelial cells stimulated with interferon-γ (IFN-γ).

  17. Towards radiation detected resonance ionization spectroscopy on transfermium elements in a buffer gas cell

    Energy Technology Data Exchange (ETDEWEB)

    Lautenschlaeger, Felix; Walther, Thomas [Institut fuer Angewandte Physik, TU Darmstadt, 64289 Darmstadt (Germany); Laatiaoui, Mustapha; Block, Michael [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, 64291 Darmstadt (Germany); Helmholtz-Institut Mainz, 55128 Mainz (Germany); Lauth, Werner; Backe, Hartmut [Institut fuer Kernphysik, JGU Mainz, 55128 Mainz (Germany); Hessberger, Fritz-Peter [GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, 64291 Darmstadt (Germany)

    2013-07-01

    The study of the atomic structure of transfermium elements like nobelium (No) and lawrencium (Lr) via Radiation Detected Resonance Ionization Spectroscopy (RADRIS) is one of the most fascinating disciplines of modern atomic physics. It allows the determination of relativistic effects at the heaviest elements and provides a critical test of theoretical predictions. For these transfermium elements no experimental data on atomic level schemes are available at present. First experiments on {sup 254}No were performed in 2007, in which a buffer gas cell with an overall efficiency of 1%. In this experiment the evaporation temperature of nobelium was determined for the first time. To increase the efficiency of the buffer gas cell, off-line measurements have been performed with nat. ytterbium, the chemical homologue of nobelium. Also on-line experiments during a parasitic beam-time in 2012 provided an insight into the critical parameters of our setup. The results of the off-line and on-line measurements are briefly summarized in this talk.

  18. Spatiotemporal multiple coherence resonances and calcium waves in a coupled hepatocyte system

    International Nuclear Information System (INIS)

    Bao-Hua, Wang; Qi-Shao, Lu; Shu-Juan, Lü; Xiu-Feng, Lang

    2009-01-01

    Spatiotemporal multiple coherence resonances for calcium activities induced by weak Gaussian white noise in coupled hepatocytes are studied. It is shown that bi-resonances in hepatocytes are induced by the interplay and competition between noise and coupling of cells, in other words, the cell in network can be excited either by noise or by its neighbour via gap junction which can transfer calcium ions between cells. Furthermore, the intercellular annular calcium waves induced by noise are observed, in which the wave length decreases with noise intensity augmenting but increases monotonically with coupling strength increasing. And for a fixed noise level, there is an optimal coupling strength that makes the coherence resonance reach maximum. (general)

  19. Resonance region neutronics of unit cells in fast and thermal reactors

    International Nuclear Information System (INIS)

    Salehi, A.A.; Driscoll, M.J.; Deutsch, O.L.

    1977-05-01

    A method has been developed for generating resonance-self-shielded cross sections based upon an improved equivalence theorem, which appears to allow extension of the self-shielding-factor (Bondarenko f-factor) method, now mainly applied to fast reactors, to thermal reactors as well. The method is based on the use of simple prescriptions for the ratio of coolant-to-fuel region-averaged fluxes, in the equations defining cell averaged cross sections. Linearization of the dependence of these functions on absorber optical thickness is found to be a necessary and sufficient condition for the existence of an equivalence theorem. Results are given for cylindrical, spherical and slab geometries. The functional form of the flux ratio relations is developed from theoretical considerations, but some of the parameters are adjusted to force-fit numerical results. Good agreement over the entire range of fuel and coolant optical thicknesses is demonstrated with numerical results calculated using the ANISN program in the S 8 P 1 option

  20. Optical resonator for a standing wave dipole trap for fermionic lithium atoms

    International Nuclear Information System (INIS)

    Elsaesser, T.

    2000-01-01

    This thesis reports on the the construction of an optical resonator for a new resonator dipole trap to store the fermionic 6 Li-isotope and to investigate its scattering properties. It was demonstrated that the resonator enhances the energy density of a (1064 nm and 40 mW) laser beam by a factor of more than 100. A fused silica vacuum cell is positioned inside the resonator under Brewster's angle. The losses of the resonator depend mainly on the optical quality of the cell. The expected trap depth of the dipole trap is 200 μK and the photon scattering rate is expected to be about 0.4 s -1 . The resonator is stabilized by means of a polarization spectroscopy method. Due to high trap frequencies, which are produced by the tight enclosure of the standing wave in the resonator, the axial motion must be quantized. A simple model to describe this quantization has been developed. A magneto-optical trap, which serves as a source of cold lithium atoms, was put in operation. (orig.)

  1. Nuclear magnetic and electric dipole moments of neon-19

    International Nuclear Information System (INIS)

    MacArthur, D.W.

    1983-01-01

    This thesis presents a detailed discussion of a series of experiments designed to measure the magnetic and electric dipole moments of the β-emitting nucleus 19 Ne. The 19 Ne is generated in the reaction 19 F(p,n) 19 Ne and is polarized by a ''stern-Gerlach'' magnet in a rare gas atomic beams machine. The atoms are stored in a cell for many seconds without depolarizing. The parity violating asymmetry in the β angular distribution is used to monitor the nuclear polarization. The polarized atoms are stored in a cell in a uniform magnetic field. The β-asymmetry is monitored by a pair of β-detectors located on either side of the cell. Transitions between the M/sub J/ = +1/2 and M/sub J/ = -1/2 spin states are induced by an rf field generated by a small Helmholtz coil pair surrounding the cell. Nuclear magnetic resonance lines are observed and the magnetic moment of 19 Ne measured to be μ( 19 Ne) = -1.88542(8)μ/sub N/. A new magnet, cell and detectors were designed to give narrow resonance lines. The equipment is described in detail and several resonance line shapes are discussed. The narrowest resonance line achieved with this system was 0.043 Hz FWHM. This width is primarily due to the 19 Ne lifetime. Pulsed NMR lineshapes were also observed. The narrow NMR lines observed in the previous experiment were then used as a probe to look for an electric dipole moment (EDM) in 19 Ne. Any shift in the resonance frequency correlated with changes in an externally applied electric field would be evidence for an EDM. The EDM of the 19 Ne atom was measured to (7.2 +/- 6.2 X 10 -22 e-cm. This experiment and possible improvements are discussed in detail

  2. Electromagnetic energy harvester for harvesting acoustic energy

    Indian Academy of Sciences (India)

    Farid U Khan

    Acoustics; energy harvesting; electromagnetic; Helmholtz resonator; sound pressure level; suspended coil. ... WSNs, which are supposed to operate for longer period of time. However ... several ambient energies such as wind, thermal, vibration, and solar are ..... textile plants in Northern India with specific reference to noise.

  3. Investigation of stroke in sickle cell disease by 1H nuclear magnetic resonance spectroscopy

    International Nuclear Information System (INIS)

    Wang, Z.; Bogdan, A.R.; Zimmermann, R.A.; Gusnard, D.A.; Leigh, J.S.; Ohene-Frempong, K.

    1992-01-01

    Localized proton nuclear magnetic resonance spectroscopy (MRS), obtained with stimulated echo and spin echo sequences, MR imaging (MRI) and MR angiography (MRA) were used to study the brain in 13 children and adolescents with sickle cell disease. Regions of interest (ROI) studied by MRS included regions appearing normal on MRI as well as regions showing complications of sickle cell disease, including focal deep white matter areas of high signal intensity (deep white matter ischemia, DWMI) seen on long TR images, focal atropic brain areas, and infarcts. The findings in these studies are summarized as follows: Normal-appearing regions on MRI have normal MRS. In ROI including small areas of DWMI, lactate elevation was not detected, but the levels of N-acetyl-aspartate (NAA) appeared slightly elevated. In areas of DWMI 1-2 cm in size, reduced blood flow could be seen on MRA and lactate elevation could be detected with MRS. When blood flow to a DWMI region was normal, NAA was reduced and there was little lactate elevation, as cell death had already occurred. ROI consisting of atrophic tissue had reduced NAA levels but total creatine levels were not changed. Sometimes lipids, presumably from broken cell membrane, could be detected. In regions of past massive stroke, all metabolites were absent except for small amounts of lactate or lipids. (orig.)

  4. Resonance – Journal of Science Education | Indian Academy of ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 7; Issue 8. Glial Cells: The Other Cells of the Nervous System - Schwann Cells – Regulators of the Periphery. Yasmin Khan Medha S Rajadhyaksha. Series Article Volume 7 Issue 8 August 2002 pp 8-15 ...

  5. Efficient models for photoionization produced by non-thermal gas discharges in air based on radiative transfer and the Helmholtz equations

    International Nuclear Information System (INIS)

    Bourdon, A; Pasko, V P; Liu, N Y; Celestin, S; Segur, P; Marode, E

    2007-01-01

    This paper presents formulation of computationally efficient models of photoionization produced by non-thermal gas discharges in air based on three-group Eddington and improved Eddington (SP 3 ) approximations to the radiative transfer equation, and on effective representation of the classic integral model for photoionization in air developed by Zheleznyak et al (1982) by a set of three Helmholtz differential equations. The reported formulations represent extensions of ideas advanced recently by Segur et al (2006) and Luque et al (2007), and allow fast and accurate solution of photoionization problems at different air pressures for the range 0.1 O 2 O 2 is the partial pressure of molecular oxygen in air in units of Torr ( p O 2 = 150 Torr) at atmospheric pressure) and R in cm is an effective geometrical size of the physical system of interest. The presented formulations can be extended to other gases and gas mixtures subject to availability of related emission, absorption and photoionization coefficients. The validity of the developed models is demonstrated by performing direct comparisons of the results from these models and results obtained from the classic integral model. Specific validation comparisons are presented for a set of artificial sources of photoionizing radiation with different Gaussian dimensions, and for a realistic problem involving development of a double-headed streamer at ground pressure. The reported results demonstrate the importance of accurate definition of the boundary conditions for the photoionization production rate for the solution of second order partial differential equations involved in the Eddington, SP 3 and the Helmholtz formulations. The specific algorithms derived from the classic photoionization model of Zheleznyak et al (1982), allowing accurate calculations of boundary conditions for differential equations involved in all three new models described in this paper, are presented. It is noted that the accurate formulation of

  6. Protein folding and wring resonances

    DEFF Research Database (Denmark)

    Bohr, Jakob; Bohr, Henrik; Brunak, Søren

    1997-01-01

    The polypeptide chain of a protein is shown to obey topological contraints which enable long range excitations in the form of wring modes of the protein backbone. Wring modes of proteins of specific lengths can therefore resonate with molecular modes present in the cell. It is suggested that prot......The polypeptide chain of a protein is shown to obey topological contraints which enable long range excitations in the form of wring modes of the protein backbone. Wring modes of proteins of specific lengths can therefore resonate with molecular modes present in the cell. It is suggested...... that protein folding takes place when the amplitude of a wring excitation becomes so large that it is energetically favorable to bend the protein backbone. The condition under which such structural transformations can occur is found, and it is shown that both cold and hot denaturation (the unfolding...

  7. Modeling the efficiency of Förster resonant energy transfer from energy relay dyes in dye-sensitized solar cells

    KAUST Repository

    Hoke, Eric T.

    2010-02-11

    Förster resonant energy transfer can improve the spectral breadth, absorption and energy conversion efficiency of dye sensitized solar cells. In this design, unattached relay dyes absorb the high energy photons and transfer the excitation to sensitizing dye molecules by Förster resonant energy transfer. We use an analytic theory to calculate the excitation transfer efficiency from the relay dye to the sensitizing dye accounting for dynamic quenching and relay dye diffusion. We present calculations for pores of cylindrical and spherical geometry and examine the effects of the Förster radius, the pore size, sensitizing dye surface concentration, collisional quenching rate, and relay dye lifetime. We find that the excitation transfer efficiency can easily exceed 90% for appropriately chosen dyes and propose two different strategies for selecting dyes to achieve record power conversion efficiencies. © 2010 Optical Society of America.

  8. Resonance self-shielding method using resonance interference factor library for practical lattice physics computations of LWRs

    International Nuclear Information System (INIS)

    Choi, Sooyoung; Khassenov, Azamat; Lee, Deokjung

    2016-01-01

    This paper presents a new method of resonance interference effect treatment using resonance interference factor for high fidelity analysis of light water reactors (LWRs). Although there have been significant improvements in the lattice physics calculations over the several decades, there exist still relatively large errors in the resonance interference treatment, in the order of ∼300 pcm in the reactivity prediction of LWRs. In the newly developed method, the impact of resonance interference to the multi-group cross-sections has been quantified and tabulated in a library which can be used in lattice physics calculation as adjustment factors of multi-group cross-sections. The verification of the new method has been performed with Mosteller benchmark, UO_2 and MOX pin-cell depletion problems, and a 17×17 fuel assembly loaded with gadolinia burnable poison, and significant improvements were demonstrated in the accuracy of reactivity and pin power predictions, with reactivity errors down to the order of ∼100 pcm. (author)

  9. Magnetic resonance imaging of thickened pituitary stalk proceeding to langerhans cell histiocytosis in a child

    International Nuclear Information System (INIS)

    Halefoglu, A.M.

    2006-01-01

    Magnetic resonance imaging has shown isolated pituitary stalk thickening in certain cases of idiopathic or secondary central diabetes insipidus (Dl) due to infiltrative processes. We present a 4-year-old boy who was initially diagnosed as having central Dl. The MRI showed isolated pituitary stalk thickening with prominent homogeneous contrast enhancement. The remaining findings on MRI were within normal limits. The patient's personal and family history and laboratory and clinical findings were unremarkable; therefore, he was initially diagnosed as having idiopathic Dl. Since central Dl and isolated pituitary stalk thickening may be considered to be the first manifestations of Langerhans cell histiocytosis, we decided to follow up the patient. After 5 months, following the initial diagnosis, on skeletal X-ray survey, the patient did indeed develop multiple lytic skull lesions which, on biopsy, were histologically typical bone lesions of Langerhans cell histiocytosis. Copyright (2006) Blackwell Science Pty Ltd

  10. Cardiac Sarcoidosis or Giant Cell Myocarditis? On Treatment Improvement of Fulminant Myocarditis as Demonstrated by Cardiovascular Magnetic Resonance Imaging

    Directory of Open Access Journals (Sweden)

    Hari Bogabathina

    2012-01-01

    Full Text Available Giant cell myocarditis, but not cardiac sarcoidosis, is known to cause fulminant myocarditis resulting in severe heart failure. However, giant cell myocarditis and cardiac sarcoidosis are pathologically similar, and attempts at pathological differentiation between the two remain difficult. We are presenting a case of fulminant myocarditis that has pathological features suggestive of cardiac sarcoidosis, but clinically mimicking giant cell myocarditis. This patient was treated with cyclosporine and prednisone and recovered well. This case we believe challenges our current understanding of these intertwined conditions. By obtaining a sense of severity of cardiac involvement via delayed hyperenhancement of cardiac magnetic resonance imaging, we were more inclined to treat this patient as giant cell myocarditis with cyclosporine. This resulted in excellent improvement of patient’s cardiac function as shown by delayed hyperenhancement images, early perfusion images, and SSFP videos.

  11. Detection of molecules and cells using nuclear magnetic resonance with magnetic nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Rümenapp, Christine, E-mail: ruemenapp@tum.de [Zentralinstitut für Medizintechnik (IMETUM), Technische Universität München, Garching (Germany); Gleich, Bernhard [Zentralinstitut für Medizintechnik (IMETUM), Technische Universität München, Garching (Germany); Mannherz, Hans Georg [Abteilung für Anatomie und Molekulare Embryologie, Ruhr Universität Bochum, Bochum (Germany); Haase, Axel [Zentralinstitut für Medizintechnik (IMETUM), Technische Universität München, Garching (Germany)

    2015-04-15

    For the detection of small molecules, proteins or even cells in vitro, functionalised magnetic nanoparticles and nuclear magnetic resonance measurements can be applied. In this work, magnetic nanoparticles with the size of 5–7 nm were functionalised with antibodies to detect two model systems of different sizes, the protein avidin and Saccharomyces cerevisiae as the model organism. The synthesised magnetic nanoparticles showed a narrow size distribution, which was determined using transmission electron microscopy and dynamic light scattering. The magnetic nanoparticles were functionalised with the according antibodies via EDC/NHS chemistry. The binding of the antigen to magnetic nanoparticles was detected through the change in the NMR T{sub 2} relaxation time at 0.5 T (≈21.7 MHz). In case of a specific binding the particles cluster and the T{sub 2} relaxation time of the sample changes. The detection limit in buffer for FITC-avidin was determined to be 1.35 nM and 10{sup 7} cells/ml for S. cerevisiae. For fluorescent microscopy the avidin molecules were labelled with FITC and for the detection of S. cerevisiae the magnetic nanoparticles were additionally functionalised with rhodamine. The binding of the particles to S. cerevisiae and the resulting clustering was also seen by transmission electron microscopy.

  12. Detection of constitutive heterodimerization of the integrin Mac-1 subunits by fluorescence resonance energy transfer in living cells

    International Nuclear Information System (INIS)

    Fu Guo; Yang Huayan; Wang Chen; Zhang Feng; You Zhendong; Wang Guiying; He Cheng; Chen Yizhang; Xu Zhihan

    2006-01-01

    Macrophage differentiation antigen associated with complement three receptor function (Mac-1) belongs to β 2 subfamily of integrins that mediate important cell-cell and cell-extracellular matrix interactions. Biochemical studies have indicated that Mac-1 is a constitutive heterodimer in vitro. Here, we detected the heterodimerization of Mac-1 subunits in living cells by means of two fluorescence resonance energy transfer (FRET) techniques (fluorescence microscopy and fluorescence spectroscopy) and our results demonstrated that there is constitutive heterodimerization of the Mac-1 subunits and this constitutive heterodimerization of the Mac-1 subunits is cell-type independent. Through FRET imaging, we found that heterodimers of Mac-1 mainly localized in plasma membrane, perinuclear, and Golgi area in living cells. Furthermore, through analysis of the estimated physical distances between cyan fluorescent protein (CFP) and yellow fluorescent protein (YFP) fused to Mac-1 subunits, we suggested that the conformation of Mac-1 subunits is not affected by the fusion of CFP or YFP and inferred that Mac-1 subunits take different conformation when expressed in Chinese hamster ovary (CHO) and human embryonic kidney (HEK) 293T cells, respectively

  13. Global Simulations of the Asymmetry in Forming Kelvin-Helmholtz Instability at Mercury

    Science.gov (United States)

    Paral, J.; Rankin, R.

    2013-12-01

    MErcury Surface, Space ENvironment, GEochemistry, and Ranging (MESSENGER) is the first spacecraft to provide data from the orbit of Mercury. After the probe's insertion into the orbit on March 2011, the in situ measurements revealed a dawn-dusk asymmetry in the observations of Kelvin-Helmholtz (KH) instability. This instability forms at the magnetopause boundary due to the high shear of the plasma flows. The asymmetry in the observations is unexpected and largely unexplained, although it has been speculated that finite ion gyroradius effect plays an important role. The large gyroradius implies that kinetic effects are important and thus must be taken into account. We employ global ion hybrid-kinetic simulations to obtain a 2D model of Mercury's magnetosphere. This code treats ions as particles and follows the full trajectory while electrons act as a charge neutralizing fluid. The planet is treated as the perfect conductor placed in the streaming solar wind to form a quasi steady state of the magnetosphere. By placing a virtual probe in the simulation domain we obtain time series of the plasma parameters which can be compared to the observations by the MESSENGER spacecraft. The comparison of the KH instability is remarkably close to the observations of MESSENGER; to within a factor of two. The model also confirms the asymmetry in the observations. The ion density obtained from the computer model is shown together with velocity vectors (represented by arrows). The solid line represents the trajectory of the third flyby of MESSENGER on September 29, 2009.

  14. Different early effect of irradiation in brain and small cell lung cancer examined by in vivo 31P-magnetic resonance spectroscopy

    DEFF Research Database (Denmark)

    Kristjansen, P E; Pedersen, A G; Quistorff, B

    1992-01-01

    Early effects of irradiation were evaluated by non-invasive in vivo 31P-magnetic resonance spectroscopy (31P-MRS) of two small cell lung cancer (SCLC) tumor lines CPH SCCL 54A and 54B, in nude mice. The tumors were originally derived from the same patient and have similar morphology and growth...

  15. Simple model for low-frequency guitar function

    DEFF Research Database (Denmark)

    Christensen, Ove; Vistisen, Bo B.

    1980-01-01

    - frequency guitar function. The model predicts frequency responce of sound pressure and top plate mobility which are in close quantitative agreement with experimental responses. The absolute sound pressure level and mobility level are predicted to within a few decibels, and the equivalent piston area......The frequency response of sound pressure and top plate mobility is studied around the two first resonances of the guitar. These resonances are shown to result from a coupling between the fundamental top plate mode and the Helmholtz resonance of the cavity. A simple model is proposed for low...

  16. Bandgap properties in locally resonant phononic crystal double panel structures with periodically attached spring–mass resonators

    Energy Technology Data Exchange (ETDEWEB)

    Qian, Denghui, E-mail: qdhsd318@163.com; Shi, Zhiyu, E-mail: zyshi@nuaa.edu.cn

    2016-10-07

    Bandgap properties of the locally resonant phononic crystal double panel structure made of a two-dimensional periodic array of a spring–mass resonator surrounded by n springs (n equals to zero at the beginning of the study) connected between the upper and lower plates are investigated in this paper. The finite element method is applied to calculate the band structure, of which the accuracy is confirmed in comparison with the one calculated by the extended plane wave expansion (PWE) method and the transmission spectrum. Numerical results and further analysis demonstrate that two bands corresponding to the antisymmetric vibration mode open a wide band gap but is cut narrower by a band corresponding to the symmetric mode. One of the regulation rules shows that the lowest frequency on the symmetric mode band is proportional to the spring stiffness. Then, a new design idea of adding springs around the resonator in a unit cell (n is not equal to zero now) is proposed in the need of widening the bandwidth and lowering the starting frequency. Results show that the bandwidth of the band gap increases from 50 Hz to nearly 200 Hz. By introducing the quality factor, the regulation rules with the comprehensive consideration of the whole structure quality limitation, the wide band gap and the low starting frequency are also discussed. - Highlights: • The locally resonant double panel structure opens a band gap in the low frequency region. • The band gap is the coupling between the symmetric and antisymmetric vibration modes. • The band structure of the double panel is the evolution of that of the single plate. • By adding springs around the resonator in a unit cell, the bandwidth gets wider. • The band gap can be controlled by tuning the parameters.

  17. Magnetic resonance imaging of prostate cancer cell lines labled with manganese chloride in vitro

    International Nuclear Information System (INIS)

    Zhuang Wenquan; Fan Huishuang; Zhang Xiaoling; Xiang Xianhong; Tang Yubo; Mao Lijuan; Zou Xuenong

    2010-01-01

    Objective: To assess the feasibility and security of prostate cancer cell lines (PC-3) labeled with manganese chloride (MnCl 2 ) for magnetic resonance imaging (MRI) in vitro. Methods: The PC-3 that purchased from American Type Culture Collection (ATCC) were recovered, cultured and amplified. The PC-3 were cultured in F-12 HAM'S medium with different concentrations of MnCl 2 in cell incubator and collected for MRI after 1 hour. The labeled cells were also collected for MRI in different amount and different time after labeling. The labeled cells were incubated with verapamil for 4 hours and the changes of the labeled cellular signal intensities were recorded in different time. Cell Counting Kit-8 (CCK-8) was used to determine the activities of the labeled cells. Results: The PC-3 labeled with MnCl 2 were high signal intensities on T 1 -weighted MRI. There were statistically significant differences between labeled cells and unlabeled cells (P 2 . The signal intensity obviously decreased after 24 hours and became to normal signal intensity of unlabeled PC-3 after 72 hours. The PC-3 labeled with 1.0 mM MnCl 2 solution showed high signal intensity on T 1 -weighted MRI with the minimum cell amount of 5.0 x 10 5 and lasted to 72 hours after a 4 hours incubation with verapamil. After 4 hours labeling, except the concentration of 0.1 mM, the other concentrations of MnCl 2 (>0.1 mM) had a certain toxicity on PC-3 (P 0.05). Conclusion: The PC-3 could be labeled with MnCl 2 and appears high signal intensity on T 1 -weighted MRI. The PC-3 can be safety labeled with MnCl 2 in concentrations which were equal or less than 1.0 mM, but the duration of Mn +2 in PC-3 is shorter. Calcium channel blocker (verapamil) may be extend the duration of PC-3 labeled with MnCl 2 . (authors)

  18. Numerical study on non-locally reacting behavior of nacelle liners incorporating drainage slots

    Science.gov (United States)

    Chen, Chao; Li, Xiaodong; Thiele, Frank

    2018-06-01

    For acoustic liners used in current commercial nacelles, in order to prevent any liquid accumulating in the resonators, drainage slots are incorporated on the partition walls between closely packed cavities. Recently, an experimental study conducted by Busse-Gerstengarbe et al. shown that the cell interaction introduced by drainage slots causes an additional dissipation peak which increases with the size of the slot. However, the variation of damping process due to drainage slots is still not fully understood. Therefore, a numerical study based on computational aeroacoustic methods is carried out to investigate the mechanism of the changed attenuation characteristics due to drainage slots in presence of grazing incident sound waves with low or high intensities. Different slot configurations are designed based on the generic non-locally reacting liner model adopted in the experimental investigation. Both 2-D and 3-D numerical simulations of only slit resonators are carried out. Numerical results indicate that the extra peak is a result of a resonance excited in the second cavity at specific frequency. Under high sound pressure level incoming waves, the basic characteristics of the acoustic performance remain. However, vortex shedding transpires at the resonances around both the slits and the drainage slot. Vorticity contours show that the connection of two coupled cavities decreases the strength of vortex shedding around the basic Helmholtz resonance due to a higher energy reflection. Meanwhile, the cell interaction significantly increases the vorticity magnitude near the extra resonant frequency. Finally, a semi-empirical model is derived to predict the extra attenuation peak frequency.

  19. Spatial confinement of ferromagnetic resonances in honeycomb antidot lattices

    International Nuclear Information System (INIS)

    Krivoruchko, V.N.; Marchenko, A.I.

    2012-01-01

    We report on a theoretical investigation of the magnetic static and dynamic properties of a thin ferromagnetic film with honeycomb lattice of circular antidots using micromagnetic simulations and analytical calculations. The theoretical model is based on the Landau–Lifshitz equations and directly accounts for the effects of the magnetic state nonuniformity. A direct calculation of local dynamic susceptibility tensor yields that the resonance spectra consist of four different quasi-uniform modes of the magnetization precession related to the confinement of magnetic domains by the hole mesh. Three of four resonant modes follow a two-fold variation with respect to the in-plane orientation of the applied magnetic field. The easy axes of these modes are mutually rotated by 60° and combine to yield the apparent six-fold configurational anisotropy. Additionally, a mode with intrinsic six-fold symmetry behavior exists, as well. Micromagnetic calculations of the local dynamic susceptibility tensor allow identifying the magnetic unit cell areas/domains responsible for each resonance mode. - Highlights: ► We study the magnetic static and dynamic properties of honeycomb antidot lattices. ► Micromagnetic simulation and analytical calculation were used. ► Four quasi-uniform precession modes exist in resonance spectra. ► The antidot unit cell areas responsible for each resonance mode were identified.

  20. Magnetic structure and resonance properties of hexagonal antidot lattice

    International Nuclear Information System (INIS)

    Marchenko, A.I.; Krivoruchko, V.N.

    2012-01-01

    Static and resonance properties of ferromagnetic films with an antidot lattice (pores in the film) are studied. The description of the system is based on micromagnetic modeling and analytical solution of the Landau-Lifshitz equation. The dependences of ferromagnetic resonance spectra on the in-plane direction of applied magnetic field and on the lattice parameters are investigated. The dependences of a dynamic system response on frequency at fixed magnetic field and on field at fixed frequency, when the field changes cause the static magnetic order to change are explored. It is found that the specific peculiarities of the system dynamics leave unchange for both of these experimental conditions. Namely, for low damping the resonance spectra contain three quasi-homogeneous modes which are due to the resonance of different regions (domains) of the antidot lattice cell. It is shown the angular field dependences of each mode are characterized by a twofold symmetry and the related easy axes are mutually rotated by 60 degrees. As the result, a hexagonal symmetry of the system static and dynamic magnetic characteristics is realized. The existence in the resonance spectrum of several quasi-homogeneous modes related to different regions of the unit cell could be fundamental for working elements of magnonic devices.

  1. Origin of strain-induced resonances in flexible terahertz metamaterials

    International Nuclear Information System (INIS)

    Sun Xiu-Yun; Li Xiao-Ning; Xu Hua; Liang Xian-Ting; Zheng Li-Ren; Zhang Xian-Peng; Lu Yue-Hui; Song Wei-Jie; Lee, Young-Pak; Rhee, Joo-Yull

    2016-01-01

    Two types of flexible terahertz metamaterials were fabricated on polyethylene naphthalate (PEN) substrates. The unit cell of one type consists of two identical split-ring resonators (SRRs) that are arranged face-to-face (i.e., FlexMetaF); the unit cell of the other type has nothing different but is arranged back-to-back (i.e., FlexMetaB). FlexMetaF and FlexMetaB illustrate the similar transmission dips under zero strain because the excitation of fundamental inductive–capacitive (LC) resonance is mainly dependent on the geometric structure of individual SRR. However, if a gradually variant strain is applied to bend FlexMetaF and FlexMetaB, the new resonant peaks appear: in the case of FlexMetaF, the peaks are located at the lower frequencies; in the case of FlexMetaB, the peaks appear at the frequencies adjacent to the LC resonance. The origin and evolution of strain-induced resonances are studied. The origin is ascribed to the detuning effect and the different responses to strain from FlexMetaF and FlexMetaB are associated with the coupling effect. These findings may improve the understanding on flexible terahertz metamaterials and benefit their applications in flexible or curved devices. (paper)

  2. Resonance probe; La sonde a resonance

    Energy Technology Data Exchange (ETDEWEB)

    Lepechinsky, D; Messiaen, A; Rolland, P [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1966-07-01

    After a brief review of papers recently published on the resonance probe as a tool for plasma diagnostics, the main features of the theory proposed by one of us are recalled. In this theory the geometry of the resonator formed by the probe, the ion sheath and the plasma is explicitly taken into account with the quasi-static and cold plasma approximations. Some new results emerging from this theory are indicated and a comparison with experimental data obtained with a spherical probe placed in a quiescent mercury-vapour plasma is made. A good quantitative agreement has been observed, indicating that the theory is satisfactory and justifying the assumptions involved. Nevertheless it appears that in some cases experimental results can only be interpreted when non collisional damping phenomena are taken into consideration. (author) [French] Apres un apercu des etudes recemment publiees sur la sonde a resonance pour le diagnostic des plasmas, on rappelle l'essentiel de la theorie proposee par l'un de nous ou il est tenu compte explicitement de la geometrie du resonateur forme par le systeme sonde-gaine ionique-plasma dans l'approximation quasi-statique et du plasma froid. On indique quelques resultats nouveaux pouvant etre tires de cette theorie et on la confronte avec les donnees experimentales obtenues pour une sonde spherique placee dans un plasma de mercure en equilibre. Un tres bon accord quantitatif a ete constate, indiquant que la theorie est satisfaisante et justifiant les approximations faites dans celle-ci. Il apparait toutefois que certains resultats experimentaux ne peuvent etre interpretes qu'en tenant compte des phenomenes d'amortissement non collisionnels. (auteur)

  3. Computational issues and applications of line-elements to model subsurface flow governed by the modified Helmholtz equation

    Science.gov (United States)

    Bakker, Mark; Kuhlman, Kristopher L.

    2011-09-01

    Two new approaches are presented for the accurate computation of the potential due to line elements that satisfy the modified Helmholtz equation with complex parameters. The first approach is based on fundamental solutions in elliptical coordinates and results in products of Mathieu functions. The second approach is based on the integration of modified Bessel functions. Both approaches allow evaluation of the potential at any distance from the element. The computational approaches are applied to model transient flow with the Laplace transform analytic element method. The Laplace domain solution is computed using a combination of point elements and the presented line elements. The time domain solution is obtained through a numerical inversion. Two applications are presented to transient flow fields, which could not be modeled with the Laplace transform analytic element method prior to this work. The first application concerns transient single-aquifer flow to wells near impermeable walls modeled with line-doublets. The second application concerns transient two-aquifer flow to a well near a stream modeled with line-sinks.

  4. Formulas for detecting a spherical stiff inclusion from interior data: a sensitivity analysis for the Helmholtz equation

    International Nuclear Information System (INIS)

    McLaughlin, Joyce; Oberai, Assad; Yoon, Jeong-Rock

    2012-01-01

    In this paper, we establish sensitivity results that are relevant for imaging stiffness in tissue but may also be useful in other contexts. The data are the displacement at a single frequency throughout the imaging domain. The goal is to determine how the quantities—(1) amplitude of displacement, or alternatively (2) the displacement itself, the average displacement, the phase or the phase gradient—change within a homogeneous stiff inclusion embedded within a homogeneous background. The results are easily interpreted formulas that show the dependence on the radius of the inclusion, the frequency and the stiffness contrast between the inclusion and the background. Our assumptions are: (1) the displacement satisfies the Helmholtz equation with the variable stiffness parameter; (2) the experiment produces a plane wave in the absence of any inclusions; (3) in 3D, the inclusion is spherical; (4) in 2D the inclusion is a circular disc; and alternatively in 3D the inclusion is an infinite circular cylinder. Our method of analysis is to use series expansions of the solution expanded about the center of the inclusion. (paper)

  5. Impedance models in time domain

    NARCIS (Netherlands)

    Rienstra, S.W.

    2005-01-01

    Necessary conditions for an impedance function are derived. Methods available in the literature are discussed. A format with recipe is proposed for an exact impedance condition in time domain on a time grid, based on the Helmholtz resonator model. An explicit solution is given of a pulse reflecting

  6. New methodology for analytical calculation of resonance integrals in an heterogeneous medium

    International Nuclear Information System (INIS)

    Campos, T.P.R. de; Martinez, A.S.

    1986-01-01

    A new methodology for analytical calculation of Resonance Integral in a typical fuel cell is presented. The expression obtained for the Resonance Integral presents the advantage of being analytical. Its constituent terms are combinations of the well known function J(xi,β) with its partial derivatives in regard to β. This is a general expression for all types of resonance. The parameters used in this method depend on the resonance type and are obtained as a function of the parameter lambda. A simple expression, depending on resonance parameters is proposed for this variable. (Author) [pt

  7. A fast resonance interference treatment scheme with subgroup method

    International Nuclear Information System (INIS)

    Cao, L.; He, Q.; Wu, H.; Zu, T.; Shen, W.

    2015-01-01

    A fast Resonance Interference Factor (RIF) scheme is proposed to treat the resonance interference effects between different resonance nuclides. This scheme utilizes the conventional subgroup method to evaluate the self-shielded cross sections of the dominant resonance nuclide in the heterogeneous system and the hyper-fine energy group method to represent the resonance interference effects in a simplified homogeneous model. In this paper, the newly implemented scheme is compared to the background iteration scheme, the Resonance Nuclide Group (RNG) scheme and the conventional RIF scheme. The numerical results show that the errors of the effective self-shielded cross sections are significantly reduced by the fast RIF scheme compared with the background iteration scheme and the RNG scheme. Besides, the fast RIF scheme consumes less computation time than the conventional RIF schemes. The speed-up ratio is ~4.5 for MOX pin cell problems. (author)

  8. Hybrid simulations of plasma transport by Kelvin-Helmholtz instability at the magnetopause: magnetic shear

    Energy Technology Data Exchange (ETDEWEB)

    Cowee, Misa M [Los Alamos National Laboratory; Winske, Dan [Los Alamos National Laboratory; Gary, S Peter [Los Alamos National Laboratory

    2009-01-01

    Two-dimensional hybrid (kinetic ions, massless fluid electrons) simulations of the Kelvin Helmholtz Instability (KHI) for a magnetopause configuration with a magnetic shear across the boundary are carried out to examine how the transport of magnetosheath plasma into the magnetosphere is affected by the shear field. Low magnetic shear conditions where the magnetosheath magnetic field is within 30{sup o} of northward is included in the simulations because KHI is thought to be important for plasma transport only for northward or near-northward interplanetary magnetic field orientations. The simulations show that coherent vortices can grow for these near-northward angles, and that they are sometimes more coherent than for pure northward conditions because the turbulence which breaks-down these vortices is reduced when there are magnetic tension forces. With increasing magnetic shear angle, the growth rate is reduced, and the vortices do not grow to as large of size which reduces the plasma transport. By tracking the individual particle motions diffusion coefficients can be obtained for the system, where the diffusion is not classical in nature but instead has a time dependence resulting from both the increasingly large-scale vortex motion and the small-scale turbulence generated in the break-down of the instabilities. Results indicate that diffusion on the order of 10{sup 9} m{sup 2}/s could possibly be generated by KHI on the flanks of the magnetosphere.

  9. The Kelvin-Helmholtz instability in National Ignition Facility hohlraums as a source of gold-gas mixing

    Energy Technology Data Exchange (ETDEWEB)

    Vandenboomgaerde, M.; Bonnefille, M.; Gauthier, P. [CEA, DAM, DIF, F-91297 Arpajon (France)

    2016-05-15

    Highly resolved radiation-hydrodynamics FCI2 simulations have been performed to model laser experiments on the National Ignition Facility. In these experiments, cylindrical gas-filled hohlraums with gold walls are driven by a 20 ns laser pulse. For the first time, simulations show the appearance of Kelvin-Helmholtz (KH) vortices at the interface between the expanding wall material and the gas fill. In this paper, we determine the mechanisms which generate this instability: the increase of the gas pressure around the expanding gold plasma leads to the aggregation of an over-dense gold layer simultaneously with shear flows. At the surface of this layer, all the conditions are met for a KH instability to grow. Later on, as the interface decelerates, the Rayleigh-Taylor instability also comes into play. A potential scenario for the generation of a mixing zone at the gold-gas interface due to the KH instability is presented. Our estimates of the Reynolds number and the plasma diffusion width at the interface support the possibility of such a mix. The key role of the first nanosecond of the laser pulse in the instability occurrence is also underlined.

  10. SIMULATIONS OF THE KELVIN–HELMHOLTZ INSTABILITY DRIVEN BY CORONAL MASS EJECTIONS IN THE TURBULENT CORONA

    Energy Technology Data Exchange (ETDEWEB)

    Gómez, Daniel O.; DeLuca, Edward E. [Harvard-Smithsonian Center for Astrophysics, 60 Garden St, Cambridge, MA 02138 (United States); Mininni, Pablo D. [Departamento de Física, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires and Instituto de Física de Buenos Aires, Ciudad Universitaria, 1428 Buenos Aires (Argentina)

    2016-02-20

    Recent high-resolution Atmospheric Imaging Assembly/Solar Dynamics Observatory images show evidence of the development of the Kelvin–Helmholtz (KH) instability, as coronal mass ejections (CMEs) expand in the ambient corona. A large-scale magnetic field mostly tangential to the interface is inferred, both on the CME and on the background sides. However, the magnetic field component along the shear flow is not strong enough to quench the instability. There is also observational evidence that the ambient corona is in a turbulent regime, and therefore the criteria for the development of the instability are a priori expected to differ from the laminar case. To study the evolution of the KH instability with a turbulent background, we perform three-dimensional simulations of the incompressible magnetohydrodynamic equations. The instability is driven by a velocity profile tangential to the CME–corona interface, which we simulate through a hyperbolic tangent profile. The turbulent background is generated by the application of a stationary stirring force. We compute the instability growth rate for different values of the turbulence intensity, and find that the role of turbulence is to attenuate the growth. The fact that KH instability is observed sets an upper limit on the correlation length of the coronal background turbulence.

  11. Supresión de modos de vibración acústicos con un resonador Helmholtz

    Directory of Open Access Journals (Sweden)

    Guiguet Andrés

    2003-01-01

    Full Text Available La inserción de un Resonador Helmholtz (RH en las paredes laterales de un tubo, con ondas estacionarias en su interior, logra suprimir uno o más de sus modos resonantes si se elige adecuadamente la frecuencia del resonador. El RH puede actuar también como filtro de ondas propagantes.' En este caso, el RH atenua las ondas en un rango de frecuencia muy selectivo. En la mayoría de los textos de acústica, solamente se desarrolla la teoría que explica el filtrado de ondas propagantes. Sin embargo, en los laboratorios de física basica, donde se dispone solamente de tubos de Kundt de pequeña longitud, no es simple realizar un arreglo experimental que asegure la presencia de ondas propagantes puras en su interior. La falta de una teoría para ondas estacionarias y las dificultades experimentales que señalamos han producido algunas confusiones en trabajos que tratan sobre el tema. En este artículo se presenta un modelo teórico que describe satisfactoriamente el comportamiento del RH cuando funciona como filtro de ondas estacionarias y se marcan las diferencias con la situación en que opera como filtro de ondas propagantes.

  12. Generalized theory of resonance excitation by sound scattering from an elastic spherical shell in a nonviscous fluid.

    Science.gov (United States)

    Mitri, Farid G

    2012-08-01

    This work presents the general theory of resonance scattering (GTRS) by an elastic spherical shell immersed in a nonviscous fluid and placed arbitrarily in an acoustic beam. The GTRS formulation is valid for a spherical shell of any size and material regardless of its location relative to the incident beam. It is shown here that the scattering coefficients derived for a spherical shell immersed in water and placed in an arbitrary beam equal those obtained for plane wave incidence. Numerical examples for an elastic shell placed in the field of acoustical Bessel beams of different types, namely, a zero-order Bessel beam and first-order Bessel vortex and trigonometric (nonvortex) beams are provided. The scattered pressure is expressed using a generalized partial-wave series expansion involving the beam-shape coefficients (BSCs), the scattering coefficients of the spherical shell, and the half-cone angle of the beam. The BSCs are evaluated using the numerical discrete spherical harmonics transform (DSHT). The far-field acoustic resonance scattering directivity diagrams are calculated for an albuminoidal shell immersed in water and filled with perfluoropropane gas, by subtracting an appropriate background from the total far-field form function. The properties related to the arbitrary scattering are analyzed and discussed. The results are of particular importance in acoustical scattering applications involving imaging and beam-forming for transducer design. Moreover, the GTRS method can be applied to investigate the scattering of any beam of arbitrary shape that satisfies the source-free Helmholtz equation, and the method can be readily adapted to viscoelastic spherical shells or spheres.

  13. In vitro evaluation of genotoxic effects under magnetic resonant coupling wireless power transfer.

    Science.gov (United States)

    Mizuno, Kohei; Shinohara, Naoki; Miyakoshi, Junji

    2015-04-07

    Wireless power transfer (WPT) technology using the resonant coupling phenomenon has been widely studied, but there are very few studies concerning the possible relationship between WPT exposure and human health. In this study, we investigated whether exposure to magnetic resonant coupling WPT has genotoxic effects on WI38VA13 subcloned 2RA human fibroblast cells. WPT exposure was performed using a helical coil-based exposure system designed to transfer power with 85.4% efficiency at a 12.5-MHz resonant frequency. The magnetic field at the positions of the cell culture dishes is approximately twice the reference level for occupational exposure as stated in the International Commission on Non-Ionizing Radiation Protection (ICNIRP) guidelines. The specific absorption rate at the positions of the cell culture dishes matches the respective reference levels stated in the ICNIRP guidelines. For assessment of genotoxicity, we studied cell growth, cell cycle distribution, DNA strand breaks using the comet assay, micronucleus formation, and hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene mutation, and did not detect any significant effects between the WPT-exposed cells and control cells. Our results suggest that WPT exposure under the conditions of the ICNIRP guidelines does not cause detectable cellular genotoxicity.

  14. Untitled

    Indian Academy of Sciences (India)

    Introduction. The majority of the commercial mufflers used on internal combustion engines contain one or more perforated tubes. These may interact with the surrounding annular cavity as in a Helmholtz resonator, or may conduct the gases as in plug mufflers and three-duct cross-flow or reverse-flow mufflers. Unfortunately,.

  15. Resonance – Journal of Science Education | Indian Academy of ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 7; Issue 6. Glial Cells: The Other Cells of the Nervous System - Oligodendrocytes – Ensheathers of the CNS. Yasmin Khan Medha S Rajadhyaksha. Series Article Volume 7 Issue 6 June 2002 pp 6-13 ...

  16. Experimental models of brain ischemia: a review of techniques, magnetic resonance imaging and investigational cell-based therapies

    Directory of Open Access Journals (Sweden)

    Alessandra eCanazza

    2014-02-01

    Full Text Available Stroke continues to be a significant cause of death and disability worldwide. Although major advances have been made in the past decades in prevention, treatment and rehabilitation, enormous challenges remain in the way of translating new therapeutic approaches from bench to bedside. Thrombolysis, while routinely used for ischemic stroke, is only a viable option within a narrow time window. Recently, progress in stem cell biology has opened up avenues to therapeutic strategies aimed at supporting and replacing neural cells in infarcted areas. Realistic experimental animal models are crucial to understand the mechanisms of neuronal survival following ischemic brain injury and to develop therapeutic interventions. Current studies on experimental stroke therapies evaluate the efficiency of neuroprotective agents and cell-based approaches using primarily rodent models of permanent or transient focal cerebral ischemia. In parallel, advancements in imaging techniques permit better mapping of the spatial-temporal evolution of the lesioned cortex and its functional responses. This review provides a condensed conceptual review of the state of the art of this field, from models and magnetic resonance imaging techniques through to stem cell therapies.

  17. Faraday waves in a Hele-Shaw cell

    Science.gov (United States)

    Li, Jing; Li, Xiaochen; Chen, Kaijie; Xie, Bin; Liao, Shijun

    2018-04-01

    We investigate Faraday waves in a Hele-Shaw cell via experimental, numerical, and theoretical studies. Inspired by the Kelvin-Helmholtz-Darcy theory, we develop the gap-averaged Navier-Stokes equations and end up with the stable standing waves with half frequency of the external forced vibration. To overcome the dependency of a numerical model on the experimental parameter of wave length, we take two-phase flow into consideration and a novel dispersion relation is derived. The numerical results compare well with our experimental data, which effectively validates our proposed mathematical model. Therefore, this model can produce robust solutions of Faraday wave patterns and resolve related physical phenomena, which demonstrates the practical importance of the present study.

  18. Magnetoacoustic Waves and the Kelvin-Helmholtz Instability in a Steady Asymmetric Slab. I: The Effects of Varying Density Ratios

    Science.gov (United States)

    Barbulescu, M.; Erdélyi, R.

    2018-06-01

    Recent observations have shown that bulk flow motions in structured solar plasmas, most evidently in coronal mass ejections (CMEs), may lead to the formation of Kelvin-Helmholtz instabilities (KHIs). Analytical models are thus essential in understanding both how the flows affect the propagation of magnetohydrodynamic (MHD) waves, and what the critical flow speed is for the formation of the KHI. We investigate both these aspects in a novel way: in a steady magnetic slab embedded in an asymmetric environment. The exterior of the slab is defined as having different equilibrium values of the background density, pressure, and temperature on either side. A steady flow and constant magnetic field are present in the slab interior. Approximate solutions to the dispersion relation are obtained analytically and classified with respect to mode and speed. General solutions and the KHI thresholds are obtained numerically. It is shown that, generally, both the KHI critical value and the cut-off speeds for magnetoacoustic waves are lowered by the external asymmetry.

  19. First Ph.D. Student Workshop of the Hermann von Helmholtz Association of National Research Centers (HGF) on ''Nuclear Safety Research''

    International Nuclear Information System (INIS)

    Knebel, J.U.; Sanchez Espinoza, V.H.

    2006-03-01

    The First Ph.D. Student Workshop ''Nuclear Safety Research'' of the Helmholtz Association of National Research Centers (HGF)'' was jointly organized by the Research Center Karlsruhe GmbH and the Energie Baden-Wuerttemberg AG (EnBW) from Wednesday 9th to Friday 11th March 2005. The workshop was opened with welcome greetings by Dr. Peter Fritz, Forschungszentrum Karlsruhe. Subsequently Dr. Joachim U. Knebel explained the main goals and the content of the workshop. The young scientists reported in 28 high-level presentations about their research work which covered a wide spectrum from reactor safety, partitions and transmutation, and innovative reactor systems, to safety research for nuclear waste disposal. The junior researchs showed excellent professional competence and demonstrated presentation qualities at the highest level. The successful funding of two Virtual Institutes, namely: the ''Competence in Nuclear Technologies'' and ''Functional Characteristics of Aquatic Interfaces both co-ordinated by Forschungszentrum Karlsruhe'', by the President of the Helmholtz Association Prof. Walter Kroell was the motivation for the organization of this first Ph.D. Student Workshop. Thanks to these two Virtual Institutes, the Reseach Center Karlsruhe and Juelich together with several univer-sities i.e. RWTH Aachen, Heidelberg, Karlsruhe, Muenster, and Stuttgart, have successfully financed eight Ph.D. and two post-doctoral students. Moreover, young scientists of the European Institute for Transuranium Elements (ITU) and additional seven Ph.D. Students, who are sponsored by the German nuclear industry (Framatome ANP, RWE Power, EnBW) in the frame of the Alliance Competence in on Nuclear Technology, and who are trained at Forschungszentrum Karlsruhe, actively contributed to this workshop. The EnBW-Award was handed over by Dr. Hans-Josef Zimmer, member of the board of directors of the EnBW-Kraftwerksgesellschaft, to Mrs. Ayelet Walter from the University of Stuttgart for the best

  20. Resonance – Journal of Science Education | Indian Academy of ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 7; Issue 4. Glial Cells: The Other Cells of the Nervous System - Astrocytes – Star Performers in the Neural Tissue. Medha S Rajadhyaksha Daya Manghani. Series Article Volume 7 Issue 4 April 2002 pp 20-26 ...

  1. Ferromagnetic resonance in a topographically modulated permalloy film

    Science.gov (United States)

    Sklenar, J.; Tucciarone, P.; Lee, R. J.; Tice, D.; Chang, R. P. H.; Lee, S. J.; Nevirkovets, I. P.; Heinonen, O.; Ketterson, J. B.

    2015-04-01

    A major focus within the field of magnonics involves the manipulation and control of spin-wave modes. This is usually done by patterning continuous soft magnetic films. Here, we report on work in which we use topographic modifications of a continuous magnetic thin film, rather than lithographic patterning techniques, to modify the ferromagnetic resonance spectrum. To demonstrate this technique we have performed in-plane, broadband, ferromagnetic resonance studies on a 100-nm-thick permalloy film sputtered onto a colloidal crystal with individual sphere diameters of 200 nm. Effects resulting from the, ideally, sixfold-symmetric underlying colloidal crystal were studied as a function of the in-plane field angle through experiment and micromagnetic modeling. Experimentally, we find two primary modes; the ratio of the intensities of these two modes exhibits a sixfold dependence. Detailed micromagnetic modeling shows that both modes are quasiuniform and nodeless in the unit cell but that they reside in different demagnetized regions of the unit cell. Our results demonstrate that topographic modification of magnetic thin films opens additional directions for manipulating ferromagnetic resonant excitations.

  2. Improving the spectral analysis of Fluorescence Resonance Energy Transfer in live cells: application to interferon receptors and Janus kinases.

    Science.gov (United States)

    Krause, Christopher D; Digioia, Gina; Izotova, Lara S; Pestka, Sidney

    2013-10-01

    The observed Fluorescence Resonance Energy Transfer (FRET) between fluorescently labeled proteins varies in cells. To understand how this variation affects our interpretation of how proteins interact in cells, we developed a protocol that mathematically separates donor-independent and donor-dependent excitations of acceptor, determines the electromagnetic interaction of donors and acceptors, and quantifies the efficiency of the interaction of donors and acceptors. By analyzing large populations of cells, we found that misbalanced or insufficient expression of acceptor or donor as well as their inefficient or reversible interaction influenced FRET efficiency in vivo. Use of red-shifted donors and acceptors gave spectra with less endogenous fluorescence but produced lower FRET efficiency, possibly caused by reduced quenching of red-shifted fluorophores in cells. Additionally, cryptic interactions between jellyfish FPs artefactually increased the apparent FRET efficiency. Our protocol can distinguish specific and nonspecific protein interactions even within highly constrained environments as plasma membranes. Overall, accurate FRET estimations in cells or within complex environments can be obtained by a combination of proper data analysis, study of sufficient numbers of cells, and use of properly empirically developed fluorescent proteins. Copyright © 2013 Elsevier Ltd. All rights reserved.

  3. Characterization of proton exchange membrane materials for fuel cells by solid state nuclear magnetic resonance

    Energy Technology Data Exchange (ETDEWEB)

    Kong, Zueqian [Iowa State Univ., Ames, IA (United States)

    2010-01-01

    Solid-state nuclear magnetic resonance (NMR) has been used to explore the nanometer-scale structure of Nafion, the widely used fuel cell membrane, and its composites. We have shown that solid-state NMR can characterize chemical structure and composition, domain size and morphology, internuclear distances, molecular dynamics, etc. The newly-developed water channel model of Nafion has been confirmed, and important characteristic length-scales established. Nafion-based organic and inorganic composites with special properties have also been characterized and their structures elucidated. The morphology of Nafion varies with hydration level, and is reflected in the changes in surface-to-volume (S/V) ratio of the polymer obtained by small-angle X-ray scattering (SAXS). The S/V ratios of different Nafion models have been evaluated numerically. It has been found that only the water channel model gives the measured S/V ratios in the normal hydration range of a working fuel cell, while dispersed water molecules and polymer ribbons account for the structures at low and high hydration levels, respectively.

  4. Low losses left-handed materials with optimized electric and magnetic resonance

    Science.gov (United States)

    Zhou, Xin; Liu, Yahong; Zhao, Xiaopeng

    2010-03-01

    We propose that the losses in left-handed materials (LHMs) can be significantly affected by changing the coupling relationship between electric and magnetic resonance. A double bowknot shaped structure (DBS) is used to construct the LHMs. And the magnetic resonance of the DBS, which resonated in the case of lower and higher frequencies than the electric resonant dip, is studied in simulation and experiment by tailoring the structural parameters. The case of magnetic resonance located at low electric resonance frequencies band is confirmed to have relatively low losses. Using full wave simulation of prism shaped structure composed of DBS unit cells, we prove the negative refraction behavior in such a frame. This study can serve as a guide for designing other similar metal-dielectric-metal (MDM) in low losses at terahertz or higher frequencies.

  5. In Vitro Evaluation of Genotoxic Effects under Magnetic Resonant Coupling Wireless Power Transfer

    Directory of Open Access Journals (Sweden)

    Kohei Mizuno

    2015-04-01

    Full Text Available Wireless power transfer (WPT technology using the resonant coupling phenomenon has been widely studied, but there are very few studies concerning the possible relationship between WPT exposure and human health. In this study, we investigated whether exposure to magnetic resonant coupling WPT has genotoxic effects on WI38VA13 subcloned 2RA human fibroblast cells. WPT exposure was performed using a helical coil-based exposure system designed to transfer power with 85.4% efficiency at a 12.5-MHz resonant frequency. The magnetic field at the positions of the cell culture dishes is approximately twice the reference level for occupational exposure as stated in the International Commission on Non-Ionizing Radiation Protection (ICNIRP guidelines. The specific absorption rate at the positions of the cell culture dishes matches the respective reference levels stated in the ICNIRP guidelines. For assessment of genotoxicity, we studied cell growth, cell cycle distribution, DNA strand breaks using the comet assay, micronucleus formation, and hypoxanthine-guanine phosphoribosyltransferase (HPRT gene mutation, and did not detect any significant effects between the WPT-exposed cells and control cells. Our results suggest that WPT exposure under the conditions of the ICNIRP guidelines does not cause detectable cellular genotoxicity.

  6. Neutron slowing down in the resonance region

    International Nuclear Information System (INIS)

    Matausek, M.V.

    1971-01-01

    This paper describes the procedure for solving space, lethargy and angular dependent transport equation for resonant neutrons in cylindrical infinite reactor lattice cell. The procedure is suitable for practical application on its own or in combination with some more complex procedure

  7. THE ROLE OF KELVIN–HELMHOLTZ INSTABILITY FOR PRODUCING LOOP-TOP HARD X-RAY SOURCES IN SOLAR FLARES

    Energy Technology Data Exchange (ETDEWEB)

    Fang, Xia; Yuan, Ding; Xia, Chun; Doorsselaere, Tom Van; Keppens, Rony [Centre for Mathematical Plasma Astrophysics, Department of Mathematics, KU Leuven, Celestijnenlaan 200B, 3001 Leuven (Belgium)

    2016-12-10

    We propose a model for the formation of loop-top hard X-ray (HXR) sources in solar flares through the inverse Compton mechanism, scattering the surrounding soft X-ray (SXR) photons to higher energy HXR photons. We simulate the consequences of a flare-driven energy deposit in the upper chromosphere in the impulsive phase of single loop flares. The consequent chromosphere evaporation flows from both footpoints reach speeds up to hundreds of kilometers per second, and we demonstrate how this triggers Kelvin–Helmholtz instability (KHI) in the loop top, under mildly asymmetric conditions, or more toward the loop flank for strongly asymmetric cases. The KHI vortices further fragment the magnetic topology into multiple magnetic islands and current sheets, and the hot plasma within leads to a bright loop-top SXR source region. We argue that the magnetohydrodynamic turbulence that appears at the loop apex could be an efficient accelerator of non-thermal particles, which the island structures can trap at the loop-top. These accelerated non-thermal particles can upscatter the surrounding thermal SXR photons emitted by the extremely hot evaporated plasma to HXR photons.

  8. Absorption spectra of localized surface plasmon resonance observed in an inline/picoliter spectrometer cell fabricated by a near ultraviolet femtosecond laser

    Science.gov (United States)

    Shiraishi, Masahiko; Nishiyama, Michiko; Watanabe, Kazuhiro; Kubodera, Shoichi

    2018-03-01

    Absorption spectra based on localized surface plasmon resonance (LSPR) were obtained with an inline/picoliter spectrometer cell. The spectrometer cell was fabricated into an optical glass fiber by focusing a near UV (NUV) femtosecond laser pulses at a wavelength of 400 nm with an energy of 30 μJ. The laser beam was focused from two directions opposite to each other to fabricate a through-hole spectrometer cell. A diameter of the cell was approximately 3 μm, and the length was approximately 62.5 μm, which was nearly equal to the core diameter of the optical fiber. Liquid solution of gold nanoparticles (GNPs) with a diameter of 5-10 nm was injected into the spectrometer cell with its volume of 0.4 pL. The absorption peak centered at 518 nm was observed. An increase of absorption associated with the increase of the number of nanoparticles was in agreement with the numerical calculation based on the Lambert-Beer law.

  9. Simulation of leakage current measurement on medical devices using helmholtz coil configuration with different current flow

    Science.gov (United States)

    Sutanto, E.; Chandra, F.; Dinata, R.

    2017-05-01

    Leakage current measurement which can follow IEC standard for medical device is one of many challenges to be answered. The IEC 60601-1 has defined that the limit for a leakage current for Medical Device can be as low as 10 µA and as high as 500 µA, depending on which type of contact (applied part) connected to the patient. Most people are using ELCB (Earth-leakage circuit breaker) for safety purpose as this is the most common and available safety device in market. One type of ELCB devices is RCD (Residual Current Device) and this RCD type can measure the leakage current directly. This work will show the possibility on how Helmholtz Coil Configuration can be made to be like the RCD. The possibility is explored by comparing the magnetic field formula from each device, then it proceeds with a simulation using software EJS (Easy Java Simulation). The simulation will make sure the concept of magnetic field current cancellation follows the RCD concept. Finally, the possibility of increasing the measurement’s sensitivity is also analyzed. The sensitivity is needed to see the possibility on reaching the minimum leakage current limit defined by IEC, 0.01mA.

  10. Simulation of leakage current measurement on medical devices using helmholtz coil configuration with different current flow

    International Nuclear Information System (INIS)

    Sutanto, E; Chandra, F; Dinata, R

    2017-01-01

    Leakage current measurement which can follow IEC standard for medical device is one of many challenges to be answered. The IEC 60601-1 has defined that the limit for a leakage current for Medical Device can be as low as 10 µA and as high as 500 µA, depending on which type of contact (applied part) connected to the patient. Most people are using ELCB (Earth-leakage circuit breaker) for safety purpose as this is the most common and available safety device in market. One type of ELCB devices is RCD (Residual Current Device) and this RCD type can measure the leakage current directly. This work will show the possibility on how Helmholtz Coil Configuration can be made to be like the RCD. The possibility is explored by comparing the magnetic field formula from each device, then it proceeds with a simulation using software EJS (Easy Java Simulation). The simulation will make sure the concept of magnetic field current cancellation follows the RCD concept. Finally, the possibility of increasing the measurement’s sensitivity is also analyzed. The sensitivity is needed to see the possibility on reaching the minimum leakage current limit defined by IEC, 0.01mA. (paper)

  11. HSC-explorer: a curated database for hematopoietic stem cells.

    Science.gov (United States)

    Montrone, Corinna; Kokkaliaris, Konstantinos D; Loeffler, Dirk; Lechner, Martin; Kastenmüller, Gabi; Schroeder, Timm; Ruepp, Andreas

    2013-01-01

    HSC-Explorer (http://mips.helmholtz-muenchen.de/HSC/) is a publicly available, integrative database containing detailed information about the early steps of hematopoiesis. The resource aims at providing fast and easy access to relevant information, in particular to the complex network of interacting cell types and molecules, from the wealth of publications in the field through visualization interfaces. It provides structured information on more than 7000 experimentally validated interactions between molecules, bioprocesses and environmental factors. Information is manually derived by critical reading of the scientific literature from expert annotators. Hematopoiesis-relevant interactions are accompanied with context information such as model organisms and experimental methods for enabling assessment of reliability and relevance of experimental results. Usage of established vocabularies facilitates downstream bioinformatics applications and to convert the results into complex networks. Several predefined datasets (Selected topics) offer insights into stem cell behavior, the stem cell niche and signaling processes supporting hematopoietic stem cell maintenance. HSC-Explorer provides a versatile web-based resource for scientists entering the field of hematopoiesis enabling users to inspect the associated biological processes through interactive graphical presentation.

  12. HSC-explorer: a curated database for hematopoietic stem cells.

    Directory of Open Access Journals (Sweden)

    Corinna Montrone

    Full Text Available HSC-Explorer (http://mips.helmholtz-muenchen.de/HSC/ is a publicly available, integrative database containing detailed information about the early steps of hematopoiesis. The resource aims at providing fast and easy access to relevant information, in particular to the complex network of interacting cell types and molecules, from the wealth of publications in the field through visualization interfaces. It provides structured information on more than 7000 experimentally validated interactions between molecules, bioprocesses and environmental factors. Information is manually derived by critical reading of the scientific literature from expert annotators. Hematopoiesis-relevant interactions are accompanied with context information such as model organisms and experimental methods for enabling assessment of reliability and relevance of experimental results. Usage of established vocabularies facilitates downstream bioinformatics applications and to convert the results into complex networks. Several predefined datasets (Selected topics offer insights into stem cell behavior, the stem cell niche and signaling processes supporting hematopoietic stem cell maintenance. HSC-Explorer provides a versatile web-based resource for scientists entering the field of hematopoiesis enabling users to inspect the associated biological processes through interactive graphical presentation.

  13. Acquisition and reconstruction conditions in silico for accurate and precise magnetic resonance elastography

    Science.gov (United States)

    Yue, Jin Long; Tardieu, Marion; Julea, Felicia; Boucneau, Tanguy; Sinkus, Ralph; Pellot-Barakat, Claire; Maître, Xavier

    2017-11-01

    Magnetic resonance elastography (MRE) is a non invasive imaging modality, which holds the promise of absolute quantification of the mechanical properties of human tissues in vivo. MRE reconstruction with algebraic inversion of the Helmholtz equation upon the curl of the shear displacement field may theoretically be flawless. However, its performances are challenged by multiple experimental parameters, especially the frequency and the amplitude of the mechanical wave, the voxel size and the signal-to-noise ratio of the MRE acquisition. A point source excitation was simulated and realistic displacement fields were analytically computed to simulate MRE data sets in an isotropic, homogeneous, linearly-elastic, and half-space infinite medium. Acquisition and reconstruction methods were challenged and the joint influence of the aforementioned parameters was studied. For a given signal-to-noise ratio, the conditions on the number of voxels per wavelength were determined for optimizing voxel-wise accuracy and precision in MRE. It was shown that, once data are acquired, the reconstruction quality could even be improved by effective interpolation or decimation so data could eventually fulfill favorable conditions for mechanical characterization of the tissue. Finally, the overall outcome, which is usually computed from the three acquired motion-encoded directions, may further be improved by appropriate averaging strategies that are based on adapted curl of shear displacement field quality-weighting.

  14. Resonances, resonance functions and spectral deformations

    International Nuclear Information System (INIS)

    Balslev, E.

    1984-01-01

    The present paper is aimed at an analysis of resonances and resonance states from a mathematical point of view. Resonances are characterized as singular points of the analytically continued Lippman-Schwinger equation, as complex eigenvalues of the Hamiltonian with a purely outgoing, exponentially growing eigenfunction, and as poles of the S-matrix. (orig./HSI)

  15. Stochastic resonance and vibrational resonance in an excitable system: The golden mean barrier

    International Nuclear Information System (INIS)

    Stan, Cristina; Cristescu, C.P.; Alexandroaei, D.; Agop, M.

    2009-01-01

    We report on stochastic resonance and vibrational resonance in an electric charge double layer configuration as usually found in electrical discharges, biological cell membranes, chemical systems and nanostructures. The experiment and numerical computation show the existence of a barrier expressible in terms of the golden mean above which the two phenomena do not take place. We consider this as new evidence for the importance of the golden mean criticality in the oscillatory dynamics, in agreement with El Naschie's E-infinity theory. In our experiment, the dynamics of a charge double layer generated in the inter-anode space of a twin electrical discharge is investigated under noise-harmonic and harmonic-harmonic perturbations. In the first case, a Gaussian noise can enhance the response of the system to a weak injected periodic signal, a clear mark of stochastic resonance. In the second case, similar enhancement can appear if the noise is replaced by a harmonic perturbation with a frequency much higher than the frequency of the weak oscillation. The amplitude of the low frequency oscillation shows a maximum versus the amplitude of the high frequency perturbation demonstrating vibrational resonance. In order to model these dynamics, we derived an excitable system by modifying a biased van der Pol oscillator. The computational study considers the behaviour of this system under the same types of perturbation as in the experimental investigations and is found to give consistent results in both situations.

  16. photon-plasma: A modern high-order particle-in-cell code

    International Nuclear Information System (INIS)

    Haugbølle, Troels; Frederiksen, Jacob Trier; Nordlund, Åke

    2013-01-01

    We present the photon-plasma code, a modern high order charge conserving particle-in-cell code for simulating relativistic plasmas. The code is using a high order implicit field solver and a novel high order charge conserving interpolation scheme for particle-to-cell interpolation and charge deposition. It includes powerful diagnostics tools with on-the-fly particle tracking, synthetic spectra integration, 2D volume slicing, and a new method to correctly account for radiative cooling in the simulations. A robust technique for imposing (time-dependent) particle and field fluxes on the boundaries is also presented. Using a hybrid OpenMP and MPI approach, the code scales efficiently from 8 to more than 250.000 cores with almost linear weak scaling on a range of architectures. The code is tested with the classical benchmarks particle heating, cold beam instability, and two-stream instability. We also present particle-in-cell simulations of the Kelvin-Helmholtz instability, and new results on radiative collisionless shocks

  17. Magnetic resonance imaging tracking of human adipose derived stromal cells within three-dimensional scaffolds for bone tissue engineering

    Directory of Open Access Journals (Sweden)

    C Lalande

    2011-04-01

    Full Text Available For bone tissue engineering, human Adipose Derived Stem Cells (hADSCs are proposed to be associated with a scaffold for promoting bone regeneration. After implantation, cellularised scaffolds require a non-invasive method for monitoring their fate in vivo. The purpose of this study was to use Magnetic Resonance Imaging (MRI-based tracking of these cells, labelled with magnetic agents for in vivo longitudinal assessment. hADSCs were isolated from adipose tissue and labelled with USPIO-rhodamine (Ultrasmall SuperParamagnetic Iron Oxide. USPIO internalisation, absence of toxicity towards hADSCs, and osteogenic differentiation of the labelled cells were evaluated in standard culture conditions. Labelled cells were then seeded within a 3D porous polysaccharide-based scaffold and imaged in vitro using fluorescence microscopy and MRI. Cellularised scaffolds were implanted subcutaneously in nude mice and MRI analyses were performed from 1 to 28 d after implantation. In vitro, no effect of USPIO labelling on cell viability and osteogenic differentiation was found. USPIO were efficiently internalised by hADSCs and generated a high T2* contrast. In vivo MRI revealed that hADSCs remain detectable until 28 d after implantation and could migrate from the scaffold and colonise the area around it. These data suggested that this scaffold might behave as a cell carrier capable of both holding a cell fraction and delivering cells to the site of implantation. In addition, the present findings evidenced that MRI is a reliable technique to validate cell-seeding procedures in 3D porous scaffolds, and to assess the fate of hADSCs transplanted in vivo.

  18. Migration of iron-labeled KHYG-1 natural killer cells to subcutaneous tumors in nude mice, as detected by magnetic resonance imaging.

    Science.gov (United States)

    Mallett, Christiane L; McFadden, Catherine; Chen, Yuhua; Foster, Paula J

    2012-07-01

    A novel cell line of cytotoxic natural killer (NK) cells, KHYG-1, was examined in vivo for immunotherapy against prostate cancer. The feasibility of using magnetic resonance imaging (MRI) tracking to monitor the fate of injected NK cells following intravenous (i.v.), intraperitoneal (i.p.) and subcutaneous (s.c.) administration was assessed. PC-3M human prostate cancer cells were injected s.c. into the flank of nude mice (day 0). KHYG-1 NK cells were labeled with an iron oxide contrast agent and injected s.c., i.v. or i.p. on day 8. Mice were imaged by MRI on days 7, 9 and 12. Tumor sections were examined with fluorescence microscopy and immunohistologic staining for NK cells. NK cells were detected in the tumors by histology after all three administration routes. NK cells and fluorescence from the iron label were co-localized. Signal loss was seen in the areas around the tumors and between the tumor lobes in the s.c. group. We are the first to label this cell line of NK cells with an iron oxide contrast agent. Accumulation of NK cells was visualized by MRI after s.c. injection but not after i.v. and i.p. injection.

  19. Resonance modulation, annihilation and generation of anti-resonance and anti-phasonance in 3D neuronal systems: interplay of resonant and amplifying currents with slow dynamics.

    Science.gov (United States)

    Rotstein, Horacio G

    2017-08-01

    Subthreshold (membrane potential) resonance and phasonance (preferred amplitude and zero-phase responses to oscillatory inputs) in single neurons arise from the interaction between positive and negative feedback effects provided by relatively fast amplifying currents and slower resonant currents. In 2D neuronal systems, amplifying currents are required to be slave to voltage (instantaneously fast) for these phenomena to occur. In higher dimensional systems, additional currents operating at various effective time scales may modulate and annihilate existing resonances and generate antiresonance (minimum amplitude response) and antiphasonance (zero-phase response with phase monotonic properties opposite to phasonance). We use mathematical modeling, numerical simulations and dynamical systems tools to investigate the mechanisms underlying these phenomena in 3D linear models, which are obtained as the linearization of biophysical (conductance-based) models. We characterize the parameter regimes for which the system exhibits the various types of behavior mentioned above in the rather general case in which the underlying 2D system exhibits resonance. We consider two cases: (i) the interplay of two resonant gating variables, and (ii) the interplay of one resonant and one amplifying gating variables. Increasing levels of an amplifying current cause (i) a response amplification if the amplifying current is faster than the resonant current, (ii) resonance and phasonance attenuation and annihilation if the amplifying and resonant currents have identical dynamics, and (iii) antiresonance and antiphasonance if the amplifying current is slower than the resonant current. We investigate the underlying mechanisms by extending the envelope-plane diagram approach developed in previous work (for 2D systems) to three dimensions to include the additional gating variable, and constructing the corresponding envelope curves in these envelope-space diagrams. We find that antiresonance and

  20. Transport and phosphorylation of choline in higher plant cells. Phosphorus-31 nuclear magnetic resonance studies

    Energy Technology Data Exchange (ETDEWEB)

    Bligny, R.; Foray, M.F.; Roby, C.; Douce, R.

    1989-03-25

    When sycamore cells were suspended in basal medium containing choline, the latter was taken up by the cells very rapidly. A facilitated diffusion system appertained at low concentrations of choline and exhibited Michaelis-Menten kinetics. At higher choline concentrations simple diffusion appeared to be the principal mode of uptake. Addition of choline to the perfusate of compressed sycamore cells monitored by /sup 31/P NMR spectroscopy resulted in a dramatic accumulation of P-choline in the cytoplasmic compartment containing choline kinase and not in the vacuole. The total accumulation of P-choline over a 10-h period exhibited Michaelis-Menten kinetics. During this period, in the absence of Pi in the perfusion medium there was a marked depletion of glucose-6-P, and the cytoplasmic Pi resonance disappeared almost completely. When a threshold of cytoplasmic Pi was attained, the phosphorylation of choline was sustained by the continuous release of Pi from the vacuole although at a much lower rate. However, when 100 microM inorganic phosphate was present in the perfusion medium, externally added Pi was preferentially used to sustain P-choline synthesis. It is clear, therefore, that cytosolic choline kinase associated with a carrier-mediated transport system for choline uptake appeared as effective systems for continuously trapping cytoplasmic Pi including vacuolar Pi entering the cytoplasm.

  1. Medulloblastoma: correlation among findings of conventional magnetic resonance imaging, diffusion-weighted imaging and proton magnetic resonance spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Fonte, Mariana Vieira de Melo da; Otaduy, Maria Concepcion Garcia; Lucato, Leandro Tavares; Reed, Umbertina Conti; Leite, Claudia da Costa [Universidade de Sao Paulo (USP), Sao Paulo, SP (Brazil). Hospital das Clinicas. Inst. de Radiologia]. E-mail: mvmfonte@uol.com.br; Costa, Maria Olivia Rodrigues; Amaral, Raquel Portugal Guimaraes [Universidade de Sao Paulo (USP), Sao Paulo, SP (Brazil). Faculdade de Medicina. Dept. de Radiologia; Reed, Umbertina Conti [Universidade de Sao Paulo (USP), Sao Paulo, SP (Brazil). Faculdade de Medicina. Dept. de Neurologia; Rosemberg, Sergio [Universidade de Sao Paulo (USP), Sao Paulo, SP (Brazil). Hospital das Clinicas. Dept. de Patologia

    2008-11-15

    To correlate imaging findings of medulloblastomas at conventional magnetic resonance imaging, diffusion-weighted imaging and proton magnetic resonance spectroscopy, comparing them with data in the literature. Preoperative magnetic resonance imaging studies of nine pediatric patients with histologically confirmed medulloblastomas (eight desmoplastic medulloblastoma, and one giant cell medulloblastoma) were retrospectively reviewed, considering demographics as well as tumors characteristics such as localization, morphology, signal intensity, contrast-enhancement, dissemination, and diffusion-weighted imaging and spectroscopy findings. In most of cases the tumors were centered in the cerebellar vermis (77.8%), predominantly solid (88.9%), hypointense on T 1-weighted images and intermediate/hyperintense on T 2-FLAIR-weighted images, with heterogeneous enhancement (100%), tumor dissemination/extension (77.8%) and limited water molecule mobility (100%). Proton spectroscopy acquired with STEAM technique (n = 6) demonstrated decreased Na a / Cr ratio (83.3%) and increased Co/Cr (100%) and ml/Cr (66.7%) ratios; and with PRESS technique (n = 7) demonstrated lactate peak (57.1%). Macroscopic magnetic resonance imaging findings in association with biochemical features of medulloblastomas have been useful in the differentiation among the most frequent posterior fossa tumors. (author)

  2. Medulloblastoma: correlation among findings of conventional magnetic resonance imaging, diffusion-weighted imaging and proton magnetic resonance spectroscopy

    International Nuclear Information System (INIS)

    Fonte, Mariana Vieira de Melo da; Otaduy, Maria Concepcion Garcia; Lucato, Leandro Tavares; Reed, Umbertina Conti; Leite, Claudia da Costa; Costa, Maria Olivia Rodrigues; Amaral, Raquel Portugal Guimaraes; Reed, Umbertina Conti; Rosemberg, Sergio

    2008-01-01

    To correlate imaging findings of medulloblastomas at conventional magnetic resonance imaging, diffusion-weighted imaging and proton magnetic resonance spectroscopy, comparing them with data in the literature. Preoperative magnetic resonance imaging studies of nine pediatric patients with histologically confirmed medulloblastomas (eight desmoplastic medulloblastoma, and one giant cell medulloblastoma) were retrospectively reviewed, considering demographics as well as tumors characteristics such as localization, morphology, signal intensity, contrast-enhancement, dissemination, and diffusion-weighted imaging and spectroscopy findings. In most of cases the tumors were centered in the cerebellar vermis (77.8%), predominantly solid (88.9%), hypointense on T 1-weighted images and intermediate/hyperintense on T 2-FLAIR-weighted images, with heterogeneous enhancement (100%), tumor dissemination/extension (77.8%) and limited water molecule mobility (100%). Proton spectroscopy acquired with STEAM technique (n = 6) demonstrated decreased Na a / Cr ratio (83.3%) and increased Co/Cr (100%) and ml/Cr (66.7%) ratios; and with PRESS technique (n = 7) demonstrated lactate peak (57.1%). Macroscopic magnetic resonance imaging findings in association with biochemical features of medulloblastomas have been useful in the differentiation among the most frequent posterior fossa tumors. (author)

  3. Surface plasmon resonance effect of Cu nanoparticles in a dye sensitized solar cell

    International Nuclear Information System (INIS)

    Dhonde, Mahesh; Sahu, Kirti; Murty, V.V.S.; Nemala, Siva Sankar; Bhargava, Parag

    2017-01-01

    Highlights: •Pure and Cu-doped TiO 2 Nanoparticles are synthesized and incorporated in DSSCs. •Addition of Cu provided high surface area and reduced charge recombination due to LSPR effect. •The highest photo conversion efficiency achieved is 8.65% with J sc of 18.8 mA cm −2 . •This efficiency is 26% higher than that of pure TiO 2 DSSC. -- Abstract: Pure and copper doped titanium dioxide nanoparticles (TiO 2 NPs) for Dye Sensitized Solar Cell (DSSC) photo anodes with different doping amounts of copper (Cu) 0.1, 0.3 and 0.5 mole% are synthesized using modified sol-gel route. Addition of Cu in TiO 2 matrix can enhance absorption towards visible spectrum and can reduce the charge carrier recombination due to Localized Surface Plasmon Resonance (LSPR). The samples are characterized by X-Ray Diffraction (XRD), Scanning Electron Microscope (SEM), UV–vis spectroscopy (UV-VIS), X-ray Photoelectron Spectroscopy (XPS), Electro Chemical Impedance Spectroscopy (EIS). The crystallite size is measured by XRD and surface morphology of the samples is analyzed using SEM. UV–vis measurement shows that the influence of Cu in TiO 2 lattice altered its optical properties and extended absorption in the visible region. The resistances between different junctions of the cell are measured by EIS. The J-V measurement of the cell prepared using pure and Cu-doped TiO 2 NPs is carried out by solar simulator. The optimized Cu doped DSSC with 0.3 mole% Cu in TiO 2 shows the best power conversion efficiency of 8.65% which is approximately 26% greater than the efficiency of undoped DSSC (6.41%).

  4. A promising magnetic resonance stem cell tracer based on natural biomaterials in a biological system: manganese (II chelated to melanin nanoparticles

    Directory of Open Access Journals (Sweden)

    Liu SJ

    2018-03-01

    Full Text Available Shi-Jie Liu,1,2,* Ling-Jie Wang,1,* Ying Qiao,1 Hua Zhang,1 Li-Ping Li,1 Jing-Hua Sun,1 Sheng He,1 Wen Xu,1,2 Xi Yang,1 Wen-Wen Cai,2 Jian-Ding Li,1 Bin-Quan Wang,3 Rui-Ping Zhang2 1Medical Imaging Department, First Clinical Medical College of Shanxi Medical University, Taiyuan, Shanxi, China; 2Imaging Department, Affiliated Tumor Hospital of Shanxi Medical University, Taiyuan, Shanxi, China; 3Department of Otolaryngology, Head & Neck Surgery, The First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China *These authors contributed equally to the paper Background: Melanin and manganese are both indispensable natural substances that play crucial roles in the human body. Melanin has been used as a multimodality imaging nanoplatform for biology science research because of its natural binding ability with metal ions (eg, 64Cu2+, Fe3+, and Gd3+. Because of its effects on T1 signal enhancement, Mn-based nanoparticles have been used in magnetic resonance (MR quantitative cell tracking in vivo. Stem cell tracking in vivo is an essential technology used to characterize engrafted stem cells, including cellular viability, biodistribution, differentiation capacity, and long-term fate.Methods: In the present study, manganese(II ions chelated to melanin nanoparticles [MNP-Mn(II] were synthesized. The characteristics, stem cell labeling efficiency, and cytotoxicity of the nanoparticles were evaluated. MR imaging of the labeled stem cells in vivo and in vitro were also further performed. In T1 relaxivity (r1, MNP-Mn(II were significantly more abundant than Omniscan. Bone marrow-derived stem cells (BMSCs can be labeled easily by coincubating with MNP-Mn(II, suggesting that MNP-Mn(II had high biocompatibility.Results: Cell Counting Kit-8 assays revealed that MNP-Mn(II had almost no cytotoxicity when used to label BMSCs, even with a very high concentration (1,600 µg/mL. BMSCs labeled with MNP-Mn(II could generate a hyperintense T1 signal both in vitro

  5. Impact of neutron resonance treatments on reactor calculation

    International Nuclear Information System (INIS)

    Leszczynski, F.

    1988-01-01

    The neutron resonance treatment on reactor calculation is one of the not completely resolved problems of reactor theory. The calculation required on design, fuel management and accident analysis of nuclear reactors contains adjust coefficients and semi-empirical values introduced on the computer codes; these values are obtained comparing calculation results with experimental values and more exact calculation results. This is made when the characteristics of the analyzed system are such that this type of comparisons are possible. The impact that one fixed resonance treatment method have on the final evaluation of physics reactor parameters, reactivity, power distribution, etc., is useful to know. In this work, the differences between calculated parameters with two different methods of resonance treatment in cell calculations are shown. It is concluded that improvements on resonance treatment are necessary for growing the reliability on core calculations results. Finally, possible improvements, easy to implement in current computer codes, are presented. (Author) [es

  6. Study on 2D arbitrary geometry coupling resonance method

    International Nuclear Information System (INIS)

    He Lei; Wu Hongchun; Cao Liangzhi

    2014-01-01

    The paper firstly proposes a coupling resonance method in which subgroup method is employed in the serried peak energy region, and wavelet expansion method is employed in single peak energy region. The original subgroup model and wavelet expansion model are improved and coupled through the calculation of scattering source from subgroup to wavelet expansion, so that the self-shielding cross section in the whole energy region can be calculated accurately. To verify these theories and to prove the improvements, a PWR cell benchmark problem is calculated. It is demonstrated that, compared with other traditional multi-group resonance methods and continuous energy resonance method, this coupling resonance method has the ability to accurately calculate the whole energy region's self-shielding cross section while Keeping enough efficiency and finally has an ability to offer the accurate self-shielding parameters for latter transport, calculation. (authors)

  7. Magnetic Resonance Tracking of Endothelial Progenitor Cells Labeled with Alkyl-Polyethylenimine 2 kDa/Superparamagnetic Iron Oxide in a Mouse Lung Carcinoma Xenograft Model

    Directory of Open Access Journals (Sweden)

    Cong Chen

    2014-11-01

    Full Text Available The potential of using endothelial progenitor cells (EPCs in novel anticancer therapy and the repair of vascular injury has been increasingly recognized. In the present study, EPCs were labeled with N-alkyl-polyethylenimine 2 kDa (PEI2k-stabilized superparamagnetic iron oxide (SPIO to facilitate magnetic resonance imaging (MRI of EPCs in a mouse lung carcinoma xenograft model. EPCs derived from human peripheral blood were labeled with alkyl-PEI2k/SPIO. The viability and activity of labeled cells were evaluated using proliferation, migration, and tubulogenesis assays. Alkyl-PEI2k/SPIO-labeled EPCs were injected intravenously (group 1 or mixed and injected together with A549 cells subcutaneously (group 2 into groups of six mice with severe combined immunodeficiency. The labeling efficiency with alkyl-PEI2k/SPIO at 7 mg Fe/mL concentration was approximately 100%. Quantitative analysis of cellular iron was 6.062 ± 0.050 pg/cell. No significant effects on EPC proliferation, migration, or tubulogenesis were seen after labeling. Seventesla micro-MRI showed the presence of schistic or linear hypointense regions at the tumor margins starting from days 7 to 8 after EPC administration. This gradually extended into the inner tumor layers in group 1. In group 2, tumor growth was accompanied by dispersion of low-signal intensity regions inside the tumor. Iron-positive cells identified by Prussian blue dye were seen at the sites identified using MRI. Human CD31-positive cells and mouse CD31-positive cells were present in both groups. Labeling EPCs with alkyl-PEI2k/SPIO allows noninvasive magnetic resonance investigation of EPC involvement in tumor neovasculature and is associated with excellent biocompatibility and MRI sensitivity.

  8. Optimization of electrodynamic characteristics of the buncher-resonator for a free electron laser

    International Nuclear Information System (INIS)

    Sobenin, N.P.; Kalyuzhnyj, V.E.; Kostin, D.V.; Yarygin, S.N.; Zavadtsev, A.A.

    1994-01-01

    Selection of geometric sizes of a resonator buncher comprising 1.5 accelerating cells and linking cell is performed. When selecting the inner resonator dimensions the attention is first of all paid to minimization of E r /E z (z, γ) function in the axial region. At the same time the value of the field overstrain coefficient under a high value of effective shunt resistance is also minimized at the expense of changing the drift tube profile. 2 refs.; 2 figs.; 4 tabs

  9. AUTOSECOL: an automatic calculation of the self-shielding of heavy isotope resonances

    International Nuclear Information System (INIS)

    Grandotto-Biettoli, Marc.

    The formalism is based on separating both types of resonance effects: local energy effects creating a fine structure in the flux, and bulk effects resulting in a slow variation in the flux. Effective reaction rates are defined that, used as tables in a multigroup calculation of cells with a large pitch in regard to resonance widths, allow an exact account of the dependence of the effective integral upon fast variations in the flux. These tables are used to introduce this phenomenon of resonance self-shielding in the multigroup Apollo program for solving the neutron transport equation, they are derived from nuclear data with using some parameters relating to the physical state of the resonant isotope inside the fuel medium. The AUTOSECOL system provides a library of effective reaction rates for taking account of the resonance self-shielding effect on the neutron flux in nuclear reactor cells. Its versatility in regard to the methods previously used for solving the same problem allows a rapid testing of the consequences of considering the self-shielding effect of new isotope resonances, a following up of the evolution in nuclear data evaluation, and rapidly studying the interest lying in new data. Results obtained with AUTOSECOL are compared with those obtained when using the SECOL code for computing the effective reaction rates of 235 U, 239 Pu, 107 Ag, 109 Ag, and 241 Pu [fr

  10. Attorneys for the Ocean - Graduate Training in the Transatlantic Helmholtz Research School for Ocean System Science and Technology (HOSST/TOSST)

    Science.gov (United States)

    van den Bogaard, Christel; Dullo, Christian; Devey, Colin; Kienast, Markus; Wallace, Douglas

    2016-04-01

    The worldwide growth in population and standards of living is leading to ever increasing human pressure on the oceans: as a source of resources, a transportation/trade pathway, and a sink for pollutants. However, use of the world's ocean is not presently guided by any over-arching management plan at either national or international level. Marine science and technology provide the necessary foundation, both in terms of system understanding and observational and modeling tools, to address these issues and to ensure that management of ocean activities can be placed on the best-possible scientific footing. The transatlantic Helmholtz Research School Ocean Science and Technology pools the complementary expertise of the Helmholtz Centre for Ocean Research Kiel (GEOMAR), the Christian-Albrechts-Universität zu Kiel, Dalhousie University and the Institute for Ocean Research Enterprise (IORE), to train the next generation of researchers in the key scientific areas critical for responsible resource utilization and management of the ocean with special emphasis on our "local ocean" - the North Atlantic. The Research School is organized around three themes which encompass key sensitivities of the North Atlantic to external forcing and resource exploitation: 4D Ocean Dynamics, Ecosystem Hotspots, and Seafloor Structures. Interactions within and between these themes regulate how the ocean system responds to both anthropogenic and natural change. The HOSST/TOSST fellows gain an in-depth understanding of how these ocean systems interact, which in turn provides a solid understanding for the formulation of scientifically-sound management practices. Given the broad scope of the school, student education is two-pronged: it provides excellent institutional support where needed, including scientific input, personal support and financial incentives, while simultaneously generating an open "intellectual space" in which ingenious, often unpredictable, ideas can take root, overcoming

  11. Four-Spacecraft Magnetic Curvature and Vorticity Analyses on Kelvin-Helmholtz Waves in MHD Simulations

    Science.gov (United States)

    Kieokaew, Rungployphan; Foullon, Claire; Lavraud, Benoit

    2018-01-01

    Four-spacecraft missions are probing the Earth's magnetospheric environment with high potential for revealing spatial and temporal scales of a variety of in situ phenomena. The techniques allowed by these four spacecraft include the calculation of vorticity and the magnetic curvature analysis (MCA), both of which have been used in the study of various plasma structures. Motivated by curved magnetic field and vortical structures induced by Kelvin- Helmholtz (KH) waves, we investigate the robustness of the MCA and vorticity techniques when increasing (regular) tetrahedron sizes, to interpret real data. Here for the first time, we test both techniques on a 2.5-D MHD simulation of KH waves at the magnetopause. We investigate, in particular, the curvature and flow vorticity across KH vortices and produce time series for static spacecraft in the boundary layers. The combined results of magnetic curvature and vorticity further help us to understand the development of KH waves. In particular, first, in the trailing edge, the magnetic curvature across the magnetopause points in opposite directions, in the wave propagation direction on the magnetosheath side and against it on the magnetospheric side. Second, the existence of a "turnover layer" in the magnetospheric side, defined by negative vorticity for the duskside magnetopause, which persists in the saturation phase, is reminiscent of roll-up history. We found significant variations in the MCA measures depending on the size of the tetrahedron. This study lends support for cross-scale observations to better understand the nature of curvature and its role in plasma phenomena.

  12. In Vitro Polarized Resonance Raman Study of N719 and N719-TBP in Dye Sensitized Solar Cells

    DEFF Research Database (Denmark)

    Hassing, Søren; Jernshøj, Kit Drescher; Nguyen, Phuong Tuyet

    2016-01-01

    Abstract: The working efficiency of dye-sensitized solar cells (DSCs) depends on the long-term stability of the dye itself and on the microscopic structure of the dye-semiconductor interface. Previous experimental studies of DSCs based on ruthenium dye with bipyridine ligands (N719) adsorbed...... to the TiO2substrate applied FTIR,un-polarized Raman (RS) and un-polarized resonance Raman (RRS) spectroscopy. In the un-polarized RRS studies of N719/TiO2 – DSCs the discussion of the adsorption of N719 was based on the rather weak carbonyl or carboxyl group stretching vibrations and on minor spectral...

  13. Single and multi-band electromagnetic induced transparency-like metamaterials with coupled split ring resonators

    Science.gov (United States)

    Bagci, Fulya; Akaoglu, Baris

    2017-08-01

    We present a metamaterial configuration exhibiting single and multi-band electromagnetic induced transparency (EIT)-like properties. The unit cell of the single band EIT-like metamaterial consists of a multi-split ring resonator surrounded by a split ring resonator. The multi-split ring resonator acts as a quasi-dark or dark resonator, depending on the polarization of the incident wave, and the split ring resonator serves as the bright resonator. Combination of these two resonators results in a single band EIT-like transmission inside the stop band. EIT-like transmission phenomenon is also clearly observed in the measured transmission spectrum at almost the same frequencies for vertical and horizontal polarized waves, and the numerical results are verified for normal incidence. Moreover, multi-band transmission windows are created within a wide band by combining the two slightly different single band EIT-like metamaterial unit cells that exhibit two different coupling strengths inside a supercell configuration. Group indices as high as 123 for single band and 488 for tri-band transmission, accompanying with high transmission rates (over 80%), are achieved, rendering the metamaterial very suitable for multi-band slow light applications. It is shown that the group delay of the propagating wave can be increased and dynamically controlled by changing the polarization angle. Multi-band EIT-like transmission is also verified experimentally, and a good agreement with simulations is obtained. The proposed novel methodology for obtaining multi-band EIT, which takes advantage of a supercell configuration by hosting slightly different configured unit cells, can be utilized for easily formation and manipulation of multi-band transmission windows inside a stop band.

  14. Experimental study of resonance crossing with a Paul trap

    Directory of Open Access Journals (Sweden)

    H. Takeuchi

    2012-07-01

    Full Text Available The effect of resonance crossing on beam stability is studied systematically by employing a novel tabletop experimental tool and a multiparticle simulation code. A large number of ions are confined in a compact linear Paul trap to reproduce the collective beam behavior. We can prove that the ion plasma in the trap is physically equivalent to a charged-particle beam propagating through a strong focusing channel. The plasma confinement force is quickly ramped such that the trap operating point traverses linear and nonlinear resonance stop bands. Assuming a nonscaling fixed field alternating gradient accelerator composed of many identical FODO cells, we measure how much ion losses occur under diverse conditions. It is experimentally and numerically demonstrated that too slow resonance crossing leads to significant ion losses as expected. Particular attention must be paid to the linear coherent resonance excited at a quarter-integer tune. When the beam intensity is high, this type of linear stop band can seriously affect the beam quality even for rather fast resonance crossing. A scaling law is given of the emittance growth caused by the quarter-integer resonance crossing.

  15. Magnetic resonance spectroscopy and metabolism. Applications of proton and sup 13 C NMR to the study of glutamate metabolism in cultured glial cells and human brain in vivo

    Energy Technology Data Exchange (ETDEWEB)

    Portais, J.C.; Pianet, I.; Merle, M.; Raffard, G.; Biran, M.; Labouesse, J.; Canioni, P. (Bordeaux-2 Univ., 33 (FR)); Allard, M.; Kien, P.; Caille, J.M. (Centre Hospitalier Universitaire, 33 Bordeaux (FR))

    1991-01-01

    Nuclear magnetic resonance (NMR) spectroscopy was used to study the metabolism of cells from the central nervous system both in vitro on perchloric acid extracts obtained either from cultured tumoral cells (C6 rat glioma) or rat astrocytes in primary culture, and in vivo within the human brain. Analysis of carbon 13 NMR spectra of perchloric acid extracts prepared from cultured cells in the presence of NMR (1-{sup 13}C) glucose as substrate allowed determination of the glutamate and glutamine enrichments in both normal and tumoral cells. Preliminary results indicated large changes in the metabolism of these amino acids (and also of aspartate and alanine) in the C6 cell as compared to its normal counterpart. Localized proton NMR spectra of the human brain in vivo were obtained at 1.5 T, in order to evaluate the content of various metabolites, including glutamate, in peritumoral edema from a selected volume of 2 x 2 x 2 cm{sup 3}. N-acetyl aspartate, glutamate, phosphocreatine, creatine, choline and inositol derivative resonances were observed in 15 min spectra. N-acetyl-aspartate was found to be at a lower level in contrast to glutamate which was detected at a higher level in the injured area as compared to the controlateral unaffected side.

  16. Megalophallus as a sequela of priapism in sickle cell anemia: use of blood oxygen level-dependent magnetic resonance imaging.

    Science.gov (United States)

    Kassim, A A; Umans, H; Nagel, R L; Fabry, M E

    2000-09-01

    Priapism is a common complication of sickle cell anemia. We report a little known sequela of priapism: painless megalophallus, with significant penile enlargement. The patient had had an intense episode of priapism 9 years previously and his penis remained enlarged. Blood oxygen level-dependent magnetic resonance imaging revealed enlarged, hypoxic corpora cavernosa. Megalophallus probably resulted from permanent loss of elasticity of the tunica albuginea due to severe engorgement during the episode of priapism. This sequela needs to be recognized by physicians because no intervention is necessary and sexual function seems to remain intact.

  17. Development of a surface plasmon resonance biosensor for real-time detection of osteogenic differentiation in live mesenchymal stem cells.

    Directory of Open Access Journals (Sweden)

    Yi-Chun Kuo

    Full Text Available Surface plasmon resonance (SPR biosensors have been recognized as a useful tool and widely used for real-time dynamic analysis of molecular binding affinity because of its high sensitivity to the change of the refractive index of tested objects. The conventional methods in molecular biology to evaluate cell differentiation require cell lysis or fixation, which make investigation in live cells difficult. In addition, a certain amount of cells are needed in order to obtain adequate protein or messenger ribonucleic acid for various assays. To overcome this limitation, we developed a unique SPR-based biosensing apparatus for real-time detection of cell differentiation in live cells according to the differences of optical properties of the cell surface caused by specific antigen-antibody binding. In this study, we reported the application of this SPR-based system to evaluate the osteogenic differentiation of mesenchymal stem cells (MSCs. OB-cadherin expression, which is up-regulated during osteogenic differentiation, was targeted under our SPR system by conjugating antibodies against OB-cadherin on the surface of the object. A linear relationship between the duration of osteogenic induction and the difference in refractive angle shift with very high correlation coefficient was observed. To sum up, the SPR system and the protocol reported in this study can rapidly and accurately define osteogenic maturation of MSCs in a live cell and label-free manner with no need of cell breakage. This SPR biosensor will facilitate future advances in a vast array of fields in biomedical research and medical diagnosis.

  18. Pickup Ion Dynamics in the Outer Heliosheath Associated with the Growth of Kelvin-Helmholtz Instability at the Heliopause

    Science.gov (United States)

    Tsubouchi, K.

    2017-12-01

    A discovery of "IBEX ribbon", localized bright emission of energetic neutral atoms, has brought new insights into the plasma environment of its source region beyond the heliosphere. It has been basically established that its geometrical property is associated with the local interstellar magnetic field draped on the heliopause, and pickup ions (PUIs) in the outer heliosheath (OHS) must be its primary source particles. Understanding the PUI dynamics in OHS more in detail is our motivation for this study. We performed two-dimensional hybrid simulations to evaluate the response of PUIs to the structural variation in the heliosheath. We assumed the simulation system such that the background plasma is hot solar wind in the inner heliosheath and cold interstellar plasma in OHS, and the directions of these flows are tangential to the heliopause. Such a situation leads to the growth of Kelvin-Helmholtz instability (KHI), where the plasma mixing and turbulence excitation takes place. We identified that non-stationarity and non-uniformity emerges in the PUI density structure in a specific energy range as KHI process advances. Relevance of these results to the expected observation like IBEX ribbon will be discussed.

  19. A perfect Fresnel acoustic reflector implemented by a Fano-resonant metascreen

    KAUST Repository

    Amin, M.

    2018-04-10

    We propose a perfectly reflecting acoustic metasurface which is designed by replacing the curved segments of the traditional Fresnel reflector by flat Fano-resonant sub-wavelength unit cells. To preserve the original Fresnel focusing mechanism, the unit cell phase follows a specific phase profile which is obtained by applying the generalized Snell\\'s law and Fermat\\'s principle. The reflected curved phase fronts are thus created at the air-metasurface boundary by tailoring the metasurface dispersion as dictated by Huygens\\' principle. Since the unit cells are implemented by sub-wavelength double slit-shaped cavity resonators, the impinging sound waves are perfectly reflected producing acoustic focusing with negligible absorption. We use plane-wave solution and full-wave simulations to demonstrate the focusing effects. The simulation results closely follow the analytical predictions.

  20. A perfect Fresnel acoustic reflector implemented by a Fano-resonant metascreen

    KAUST Repository

    Amin, M.; Siddiqui, O.; Farhat, Mohamed; Khelif, A.

    2018-01-01

    We propose a perfectly reflecting acoustic metasurface which is designed by replacing the curved segments of the traditional Fresnel reflector by flat Fano-resonant sub-wavelength unit cells. To preserve the original Fresnel focusing mechanism, the unit cell phase follows a specific phase profile which is obtained by applying the generalized Snell's law and Fermat's principle. The reflected curved phase fronts are thus created at the air-metasurface boundary by tailoring the metasurface dispersion as dictated by Huygens' principle. Since the unit cells are implemented by sub-wavelength double slit-shaped cavity resonators, the impinging sound waves are perfectly reflected producing acoustic focusing with negligible absorption. We use plane-wave solution and full-wave simulations to demonstrate the focusing effects. The simulation results closely follow the analytical predictions.

  1. A perfect Fresnel acoustic reflector implemented by a Fano-resonant metascreen

    Science.gov (United States)

    Amin, M.; Siddiqui, O.; Farhat, M.; Khelif, A.

    2018-04-01

    We propose a perfectly reflecting acoustic metasurface which is designed by replacing the curved segments of the traditional Fresnel reflector by flat Fano-resonant sub-wavelength unit cells. To preserve the original Fresnel focusing mechanism, the unit cell phase follows a specific phase profile which is obtained by applying the generalized Snell's law and Fermat's principle. The reflected curved phase fronts are thus created at the air-metasurface boundary by tailoring the metasurface dispersion as dictated by Huygens' principle. Since the unit cells are implemented by sub-wavelength double slit-shaped cavity resonators, the impinging sound waves are perfectly reflected producing acoustic focusing with negligible absorption. We use plane-wave solution and full-wave simulations to demonstrate the focusing effects. The simulation results closely follow the analytical predictions.

  2. Complementary theta resonance filtering by two spatially segregated mechanisms in CA1 hippocampal pyramidal neurons.

    Science.gov (United States)

    Hu, Hua; Vervaeke, Koen; Graham, Lyle J; Storm, Johan F

    2009-11-18

    Synaptic input to a neuron may undergo various filtering steps, both locally and during transmission to the soma. Using simultaneous whole-cell recordings from soma and apical dendrites from rat CA1 hippocampal pyramidal cells, and biophysically detailed modeling, we found two complementary resonance (bandpass) filters of subthreshold voltage signals. Both filters favor signals in the theta (3-12 Hz) frequency range, but have opposite location, direction, and voltage dependencies: (1) dendritic H-resonance, caused by h/HCN-channels, filters signals propagating from soma to dendrite when the membrane potential is close to rest; and (2) somatic M-resonance, caused by M/Kv7/KCNQ and persistent Na(+) (NaP) channels, filters signals propagating from dendrite to soma when the membrane potential approaches spike threshold. Hippocampal pyramidal cells participate in theta network oscillations during behavior, and we suggest that that these dual, polarized theta resonance mechanisms may convey voltage-dependent tuning of theta-mediated neural coding in the entorhinal/hippocampal system during locomotion, spatial navigation, memory, and sleep.

  3. The Resonance Absorption of Uranium Metal and Oxide

    Energy Technology Data Exchange (ETDEWEB)

    Hellstrand, E; Lundgren, G

    1962-06-15

    The resonance integrals for uranium metal and uranium oxide have been determined for a 1/E flux. The following results were obtained Metal RI 2.95 + 25.8{radical}(S/M); Oxide RI = 4.15 + 26.6{radical}(S/M). The oxide value agrees with the expression found earlier at this laboratory. But the result for the metal is 4. 5 % larger than the earlier one. In addition, the resonance absorption in a R1 fuel rod has been compared with that for a cadmium-covered rod placed in an approximate cell boundary flux. The former came out 3 % larger than the latter. A comparison of the fuel rod absorption with that for a 1/E flux yields a corresponding figure of 7 %. The neutron flux was monitored below the lowest resonance in uranium.

  4. An analysis of uncertainties in the reference resonance absorption calculations

    International Nuclear Information System (INIS)

    Milosevic, M.; Pesic, M.

    1997-05-01

    A recently appeared generation of design-oriented methods, which allows to compute the space and energy dependence of the resonant absorption inside the fuel rod, induces a new problem of validation of results obtained with improved resonance treatments, Because no experimental results are available on the spatial and energy distribution of resonance absorption, detailed reference calculations were generated with the continuos-energy Monte Carlo and energy pointwise slowing-down codes. The accuracy of these calculations depends>on various in.fluences. In this paper an analysis of some influences, such as differences ;n nuclear data libraries and philosophy of reproducing the cross section data, is presented. Example application is given for a calculation benchmark that consists of determination of resonance absorption by 238 U in typical PWR pin cell geometry (author)

  5. Biological responses of human solid tumor cells to X-ray irradiation within a 1.5-Tesla magnetic field generated by a magnetic resonance imaging–linear accelerator

    NARCIS (Netherlands)

    Wang, Li; Hoogcarspel, Stan Jelle; Wen, Zhifei; van Vulpen, Marco; Molkentine, David P.; Kok, Jan; Lin, Steven H.; Broekhuizen, Roel; Ang, Kie Kian; Bovenschen, Niels; Raaymakers, Bas W.; Frank, Steven J.

    2016-01-01

    Devices that combine magnetic resonance imaging with linear accelerators (MRL) represent a novel tool for MR-guided radiotherapy. However, whether magnetic fields (MFs) generated by these devices affect the radiosensitivity of tumors is unknown. We investigated the influence of a 1.5-T MF on cell

  6. Glial Cells: The Other Cells of the Nervous System

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 7; Issue 1. Glial Cells: The Other Cells of the Nervous System - An Introduction to Glial Cells. Medha S Rajadhyaksha Yasmin Khan. Series Article Volume 7 Issue 1 January 2002 pp 4-10 ...

  7. Design of a dual linear polarization antenna using split ring resonators at X-band

    Science.gov (United States)

    Ahmed, Sadiq; Chandra, Madhukar

    2017-11-01

    Dual linear polarization microstrip antenna configurations are very suitable for high-performance satellites, wireless communication and radar applications. This paper presents a new method to improve the co-cross polarization discrimination (XPD) for dual linear polarized microstrip antennas at 10 GHz. For this, three various configurations of a dual linear polarization antenna utilizing metamaterial unit cells are shown. In the first layout, the microstrip patch antenna is loaded with two pairs of spiral ring resonators, in the second model, a split ring resonator is placed between two microstrip feed lines, and in the third design, a complementary split ring resonators are etched in the ground plane. This work has two primary goals: the first is related to the addition of metamaterial unit cells to the antenna structure which permits compensation for an asymmetric current distribution flow on the microstrip antenna and thus yields a symmetrical current distribution on it. This compensation leads to an important enhancement in the XPD in comparison to a conventional dual linear polarized microstrip patch antenna. The simulation reveals an improvement of 7.9, 8.8, and 4 dB in the E and H planes for the three designs, respectively, in the XPD as compared to the conventional dual linear polarized patch antenna. The second objective of this paper is to present the characteristics and performances of the designs of the spiral ring resonator (S-RR), split ring resonator (SRR), and complementary split ring resonator (CSRR) metamaterial unit cells. The simulations are evaluated using the commercial full-wave simulator, Ansoft High-Frequency Structure Simulator (HFSS).

  8. Possible physics program with a large acceptance hyperon spectrometer at J-PARC

    International Nuclear Information System (INIS)

    Imai, Kenichi

    2013-01-01

    We are going to construct a large acceptance hyperon spectrometer (HypTPC) at J-PARC primarily to search for H-dibaryon. The HypTPC consists of a superconducting Helmholtz magnet and a Time Projection Chamber (TPC). The short-life hyperons can be detected with high precision as well as any charged particles. Here, we discuss possible physics programs other than H-dibaryon which can be done with this spectrometer, such as a nucleon resonance spectroscopy experiment, systematic study of Λ(1405) and spectroscopy of Ξ and Ω - resonances. (author)

  9. Effect of eddy current damping on phononic band gaps generated by locally resonant periodic structures

    Science.gov (United States)

    Ozkaya, Efe; Yilmaz, Cetin

    2017-02-01

    The effect of eddy current damping on a novel locally resonant periodic structure is investigated. The frequency response characteristics are obtained by using a lumped parameter and a finite element model. In order to obtain wide band gaps at low frequencies, the periodic structure is optimized according to certain constraints, such as mass distribution in the unit cell, lower limit of the band gap, stiffness between the components in the unit cell, the size of magnets used for eddy current damping, and the number of unit cells in the periodic structure. Then, the locally resonant periodic structure with eddy current damping is manufactured and its experimental frequency response is obtained. The frequency response results obtained analytically, numerically and experimentally match quite well. The inclusion of eddy current damping to the periodic structure decreases amplitudes of resonance peaks without disturbing stop band width.

  10. Investigation of exhaust gases at blends of fuels/biofuels at the Helmholtz Virtual Institute for Complex Molecular Systems in Environmental Health; Abgasuntersuchungen an Kraftstoffen/Biokraftstoff-Blends im Rahmen des Helmholtz Virtual Institute for Complex Molecular Systems in Environmental Health

    Energy Technology Data Exchange (ETDEWEB)

    Streibel, Thorsten [Rostock Univ. (Germany). Inst. fuer Chemie, Analytische Chemie; Adam, Thomas; Grabowsky, Jana; Sklorz, Martin; Zimmermann, Ralf

    2012-07-01

    The objective of the ''Helmholtz Virtual Institute of Complex Molecular Systems in Environmental Health'' (HICE) is the establishment of a long-term scientific research initiative for the investigation of the causes and mechanisms of environmentally influenced diseases. In the initial phase (INF funding period) the HICE focuses on a deeper understanding of the impact of anthropogenic aerosols on human health. Based on current hypotheses, reactive organic compounds in particle as well as in gas phase of aerosols are particularly relevant. Innovative in-vitro human lung tissue models and selected susceptible animal models are exposed to aerosols, and separated gas and particle phases from relevant sources. The response of the biological systems is investigated by state-of-the-art analytical techniques on different biological levels (transcriptome, proteome, metabolome, toxicological parameters). The second central topic is the real-time characterization of emissions (gas- and particulate phase) from internal combustion engines with a special focus on the influence of the biodiesel content. For this, mass spectrometry with photo ionization will be applied for the detection of organic compounds. Preliminary studies dealt with the online investigation of the gas phase of truck diesel exhaust as well as the offline particulate phase characterization after thermal desorption. Both studies detected primarily (poly)aromatic hydrocarbons. (orig.)

  11. Optimum condition for spatial ion cyclotron resonance in a multiple magnetic mirror field

    International Nuclear Information System (INIS)

    Mieno, Tetsu; Hatakeyama, Rikizo; Sato, Noriyoshi

    1988-01-01

    A Spatial cyclotron resonance of ion beams passing through a multiple magnetic mirror field is investigated experimentally by varying parameters of the multiple mirror field. The optimum resonance condition is realized with a decrease in the cell length of the multiple mirror along the beams to satisfy the local condition of the spatial ion cyclotron resonance. The results show a remarkable increase of nonadiabatic transfer of the beam energy into the transverse direction to the magnetic field. (author)

  12. Efficient primary and parametric resonance excitation of bistable resonators

    KAUST Repository

    Ramini, Abdallah

    2016-09-12

    We experimentally demonstrate an efficient approach to excite primary and parametric (up to the 4th) resonance of Microelectromechanical system MEMS arch resonators with large vibrational amplitudes. A single crystal silicon in-plane arch microbeam is fabricated such that it can be excited axially from one of its ends by a parallel-plate electrode. Its micro/nano scale vibrations are transduced using a high speed camera. Through the parallel-plate electrode, a time varying electrostatic force is applied, which is converted into a time varying axial force that modulates dynamically the stiffness of the arch resonator. Due to the initial curvature of the structure, not only parametric excitation is induced, but also primary resonance. Experimental investigation is conducted comparing the response of the arch near primary resonance using the axial excitation to that of a classical parallel-plate actuation where the arch itself forms an electrode. The results show that the axial excitation can be more efficient and requires less power for primary resonance excitation. Moreover, unlike the classical method where the structure is vulnerable to the dynamic pull-in instability, the axial excitation technique can provide large amplitude motion while protecting the structure from pull-in. In addition to primary resonance, parametrical resonances are demonstrated at twice, one-half, and two-thirds the primary resonance frequency. The ability to actuate primary and/or parametric resonances can serve various applications, such as for resonator based logic and memory devices. (C) 2016 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license

  13. Electromagnetically induced transparency in planar metamaterials based on guided mode resonance

    Science.gov (United States)

    Sun, Yaru; Chen, Hang; Li, Xiangjun; Hong, Zhi

    2017-06-01

    We present and numerically demonstrate a novel, electromagnetically induced transparency (EIT) in planar metamaterials (MMs) based on guided mode resonance (GMR). The unit cell of the MM consists of two metallic ring resonators. The GMR with high quality factor (Q) is achieved by changing the distance between the two rings of the MM. Narrow EIT-like spectral response is realized by coupling between a high Q GMR and a low Q dipolar resonance of the MM. Our work could provide another efficient way towards the realization of EIT with large group index using very simple structures.

  14. Resonant tunneling diodes as energy-selective contacts used in hot-carrier solar cells

    International Nuclear Information System (INIS)

    Takeda, Yasuhiko; Sugimoto, Noriaki; Ichiki, Akihisa; Kusano, Yuya; Motohiro, Tomoyoshi

    2015-01-01

    Among the four features unique to hot-carrier solar cells (HC-SCs): (i) carrier thermalization time and (ii) carrier equilibration time in the absorber, (iii) energy-selection width and (iv) conductance of the energy-selective contacts (ESCs), requisites of (i)-(iii) for high conversion efficiency have been clarified. We have tackled the remaining issues related to (iv) in the present study. The detailed balance model of HC-SC operation has been improved to involve a finite value of the ESC conductance to find the required values, which in turn has been revealed to be feasible using resonant tunneling diodes (RTDs) consisting of semiconductor quantum dots (QDs) and quantum wells (QWs) by means of a formulation to calculate the conductance of the QD- and QW-RTDs derived using the rigorous solutions of the effective-mass Hamiltonians. Thus, all of the four requisites unique to HC-SCs to achieve high conversion efficiency have been elucidated, and the two requisites related to the ESCs can be fulfilled using the QD- and QW-RTDs

  15. Resonant tunneling diodes as energy-selective contacts used in hot-carrier solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Takeda, Yasuhiko, E-mail: takeda@mosk.tytlabs.co.jp; Sugimoto, Noriaki [Toyota Central Research and Development Laboratories, Inc., 41-1, Yokomichi, Nagakute, Aichi 480-1192 (Japan); Ichiki, Akihisa [Green Mobility Collaborative Research Center, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601 (Japan); Kusano, Yuya [Green Mobility Collaborative Research Center, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601 (Japan); Toyota Motor Corp., 1200 Mishuku, Susono, Shizuoka 410-1193 (Japan); Motohiro, Tomoyoshi [Toyota Central Research and Development Laboratories, Inc., 41-1, Yokomichi, Nagakute, Aichi 480-1192 (Japan); Green Mobility Collaborative Research Center, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601 (Japan); Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601 (Japan)

    2015-09-28

    Among the four features unique to hot-carrier solar cells (HC-SCs): (i) carrier thermalization time and (ii) carrier equilibration time in the absorber, (iii) energy-selection width and (iv) conductance of the energy-selective contacts (ESCs), requisites of (i)-(iii) for high conversion efficiency have been clarified. We have tackled the remaining issues related to (iv) in the present study. The detailed balance model of HC-SC operation has been improved to involve a finite value of the ESC conductance to find the required values, which in turn has been revealed to be feasible using resonant tunneling diodes (RTDs) consisting of semiconductor quantum dots (QDs) and quantum wells (QWs) by means of a formulation to calculate the conductance of the QD- and QW-RTDs derived using the rigorous solutions of the effective-mass Hamiltonians. Thus, all of the four requisites unique to HC-SCs to achieve high conversion efficiency have been elucidated, and the two requisites related to the ESCs can be fulfilled using the QD- and QW-RTDs.

  16. Effect of ion clouds micromotion on measured signal in Fourier transform ion cyclotron resonance: Computer simulation.

    Science.gov (United States)

    Vladimirov, Gleb; Kostyukevich, Yury; Kharybin, Oleg; Nikolaev, Eugene

    2017-08-01

    Particle-in-cell-based realistic simulation of Fourier transform ion cyclotron resonance experiments could be used to generate ion trajectories and a signal induced on the detection electrodes. It has been shown recently that there is a modulation of "reduced" cyclotron frequencies in ion cyclotron resonance signal caused by Coulomb interaction of ion clouds. In this work it was proposed to use this modulation in order to determine frequency difference between an ion of known m/z and all other ions generating signal in ion cyclotron resonance cell. It is shown that with an increase of number of ions in ion cyclotron resonance trap, the modulation index increases, which lead to a decrease in the accuracy of determination of peak intensities by super Fourier transform resolution methods such as filter diagonalization method.

  17. Cyclotron resonance for electrons over helium in resonator

    CERN Document Server

    Shikin, V B

    2002-01-01

    The problem on the cyclotron resonance (CR) for electrons on the helium film, positioned in the resonator lower part, is solved. It is shown, that it relates to one of the examples of the known problem on the oscillations of the coupled oscillators system. The coupling constant between these oscillators constituting the variable function of the problem parameters. It is minimal in the zero magnetic field and reaches its maximum under the resonance conditions, when the cyclotron frequency coincides with one of the resonator modes. The CR details of the Uhf CR-energy absorption coupled by the electrons + resonator system, are calculated. The applications of the obtained results to the available CR experiments for electrons over helium

  18. Microstrip resonators for electron paramagnetic resonance experiments

    Science.gov (United States)

    Torrezan, A. C.; Mayer Alegre, T. P.; Medeiros-Ribeiro, G.

    2009-07-01

    In this article we evaluate the performance of an electron paramagnetic resonance (EPR) setup using a microstrip resonator (MR). The design and characterization of the resonator are described and parameters of importance to EPR and spin manipulation are examined, including cavity quality factor, filling factor, and microwave magnetic field in the sample region. Simulated microwave electric and magnetic field distributions in the resonator are also presented and compared with qualitative measurements of the field distribution obtained by a perturbation technique. Based on EPR experiments carried out with a standard marker at room temperature and a MR resonating at 8.17 GHz, the minimum detectable number of spins was found to be 5×1010 spins/GHz1/2 despite the low MR unloaded quality factor Q0=60. The functionality of the EPR setup was further evaluated at low temperature, where the spin resonance of Cr dopants present in a GaAs wafer was detected at 2.3 K. The design and characterization of a more versatile MR targeting an improved EPR sensitivity and featuring an integrated biasing circuit for the study of samples that require an electrical contact are also discussed.

  19. Microstrip resonators for electron paramagnetic resonance experiments.

    Science.gov (United States)

    Torrezan, A C; Mayer Alegre, T P; Medeiros-Ribeiro, G

    2009-07-01

    In this article we evaluate the performance of an electron paramagnetic resonance (EPR) setup using a microstrip resonator (MR). The design and characterization of the resonator are described and parameters of importance to EPR and spin manipulation are examined, including cavity quality factor, filling factor, and microwave magnetic field in the sample region. Simulated microwave electric and magnetic field distributions in the resonator are also presented and compared with qualitative measurements of the field distribution obtained by a perturbation technique. Based on EPR experiments carried out with a standard marker at room temperature and a MR resonating at 8.17 GHz, the minimum detectable number of spins was found to be 5 x 10(10) spins/GHz(1/2) despite the low MR unloaded quality factor Q0=60. The functionality of the EPR setup was further evaluated at low temperature, where the spin resonance of Cr dopants present in a GaAs wafer was detected at 2.3 K. The design and characterization of a more versatile MR targeting an improved EPR sensitivity and featuring an integrated biasing circuit for the study of samples that require an electrical contact are also discussed.

  20. Microtubules in biological cells as circular waveguides and resonators

    Czech Academy of Sciences Publication Activity Database

    Jelínek, František; Pokorný, Jiří

    2001-01-01

    Roč. 20, č. 1 (2001), s. 75-80 ISSN 1061-9526. [Electromagnetic Aspects of Selforganization in Biology. Prague, 09.07.2000-12.07.2000] R&D Projects: GA ČR GA102/97/0867 Grant - others:EU COST (XE) OC 244BIS.10 Institutional research plan: CEZ:AV0Z2067918 Keywords : cellular biophysics * waveguides * resonators Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering Impact factor: 0.333, year: 2001

  1. Acoustic Wave Propagation in Pressure Sense Lines

    Science.gov (United States)

    Vitarius, Patrick; Gregory, Don A.; Wiley, John; Korman, Valentin

    2003-01-01

    Sense lines are used in pressure measurements to passively transmit information from hostile environments to areas where transducers can be used. The transfer function of a sense line can be used to obtain information about the measured environment from the protected sensor. Several properties of this transfer function are examined, including frequency dependence, Helmholtz resonance, and time of flight delay.

  2. Multiphoton resonances

    International Nuclear Information System (INIS)

    Shore, B.W.

    1977-01-01

    The long-time average of level populations in a coherently-excited anharmonic sequence of energy levels (e.g., an anharmonic oscillator) exhibits sharp resonances as a function of laser frequency. For simple linearly-increasing anharmonicity, each resonance is a superposition of various multiphoton resonances (e.g., a superposition of 3, 5, 7, . . . photon resonances), each having its own characteristic width predictable from perturbation theory

  3. VCAM-1-targeted core/shell nanoparticles for selective adhesion and delivery to endothelial cells with lipopolysaccharide-induced inflammation under shear flow and cellular magnetic resonance imaging in vitro.

    Science.gov (United States)

    Yang, Hong; Zhao, Fenglong; Li, Ying; Xu, Mingming; Li, Li; Wu, Chunhui; Miyoshi, Hirokazu; Liu, Yiyao

    2013-01-01

    Multifunctional nanomaterials with unique magnetic and luminescent properties have broad potential in biological applications. Because of the overexpression of vascular cell adhesion molecule-1 (VCAM-1) receptors in inflammatory endothelial cells as compared with normal endothelial cells, an anti-VCAM-1 monoclonal antibody can be used as a targeting ligand. Herein we describe the development of multifunctional core-shell Fe(3)O(4)@SiO2 nanoparticles with the ability to target inflammatory endothelial cells via VCAM-1, magnetism, and fluorescence imaging, with efficient magnetic resonance imaging contrast characteristics. Superparamagnetic iron oxide and fluorescein isothiocyanate (FITC) were loaded successfully inside the nanoparticle core and the silica shell, respectively, creating VCAM-1-targeted Fe(3)O(4)@SiO2(FITC) nanoparticles that were characterized by scanning electron microscopy, transmission electron microscopy, fluorescence spectrometry, zeta potential assay, and fluorescence microscopy. The VCAM-1-targeted Fe(3)O(4)@SiO2(FITC) nanoparticles typically had a diameter of 355 ± 37 nm, showed superparamagnetic behavior at room temperature, and cumulative and targeted adhesion to an inflammatory subline of human umbilical vein endothelial cells (HUVEC-CS) activated by lipopolysaccharide. Further, our data show that adhesion of VCAM-1-targeted Fe(3)O(4)@SiO2(FITC) nanoparticles to inflammatory HUVEC-CS depended on both shear stress and duration of exposure to stress. Analysis of internalization into HUVEC-CS showed that the efficiency of delivery of VCAM-1-targeted Fe(3)O(4)@SiO2(FITC) nanoparticles was also significantly greater than that of nontargeted Fe(3)O(4)@SiO2(FITC)-NH2 nanoparticles. Magnetic resonance images showed that the superparamagnetic iron oxide cores of the VCAM-1-targeted Fe(3)O(4)@SiO2(FITC) nanoparticles could also act as a contrast agent for magnetic resonance imaging. Taken together, the cumulative adhesion and uptake potential of

  4. Resonance – Journal of Science Education | Indian Academy of ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 22; Issue 10. Science Academies' Refresher Course on Experimental Approaches to Molecular Microbiology and Cell Biology. Information and Announcements Volume 22 Issue 10 October 2017 pp 971-971 ...

  5. Magnetic resonance annual 1986

    International Nuclear Information System (INIS)

    Kressel, H.Y.

    1986-01-01

    This book contains papers written on magnetic resonance during 1986. Topics include: musculosketetal magnetic resonance imaging; imaging of the spine; magnetic resonance chemical shift imaging; magnetic resonance imaging in the central nervous system; comparison to computed tomography; high resolution magnetic resonance imaging using surface coils; magnetic resonance imaging of the chest; magnetic resonance imaging of the breast; magnetic resonance imaging of the liver; magnetic resonance spectroscopy of neoplasms; blood flow effects in magnetic resonance imaging; and current and potential applications of clinical sodium magnetic resonance imaging

  6. Weak Depolarizing Resonances in the 3-TeV VLHC Booster

    International Nuclear Information System (INIS)

    Anferov, V.A.

    1999-01-01

    The possibility of polarized-proton-beam acceleration in the proposed low-field 3-TeV VLHC booster is considered. We find that the low-field combined function magnets in the booster's long FODO cells cause an inadvertent cancellation of most depolarizing fields due to a mechanism suggested earlier by Chao and Derbenev [Part.Accel.36, 25 (1991)]. The strongest spin-depolarizing resonances in the 3-TeV booster seem to be similar in strength to those in the 250-GeV RHIC. Moreover, the strength of the 3-TeV booster's strongest intrinsic depolarizing resonances decreases with energy, in contrast with the energy growth of the depolarizing resonance's strength in most proton synchrotrons. copyright 1999 The American Physical Society

  7. Reflector stack optimization for Bulk Acoustic Wave resonators

    NARCIS (Netherlands)

    Jose, Sumy

    2011-01-01

    Thin-film bulk-acoustic-wave (BAW) devices are used for RF selectivity in mobile communication system and other wireless applications. Currently, the conventional RF filters are getting replaced by BAW filters in all major cell phone standards. In this thesis, we study solidly mounted BAW resonators

  8. Nitroxide radicals as contrast substances for magnetic resonance imaging diagnostics. Part 1

    International Nuclear Information System (INIS)

    Zhelev, Z.

    2016-01-01

    In last ten years, there is a significant progress in the selective and localized detection of redox-active compounds in the cells, tissues, and intact organisms. This progress is due to the development of new synthetic and genetically encoded redox-sensitive contrast substances, as well as due to the improvement of the techniques for their imaging: fluorescent, chemiluminescent, magnetic resonance, nuclear, ultrasonic. One of the most attractive redox-sensitive contrast substances are cyclic (stable) nitroxide radicals. They can be visualized and analyzed in vitro and in vivo by a variety of magnetic resonance techniques - electron-paramagnetic resonance imaging (EPRI), magnetic resonance imaging (MRI), Overhauser-enhanced MRI (OMRI). This review describes the merits and demerits of the nitroxide-enhanced EPR and MRI and the perspectives for their application in biomedical studies and clinical practice. The article is intended for a wide range of readers - from students to specialists in the field. Key words: Magnetic Resonance Imaging (MRI). Electron-Paramagnetic Resonance (EPR). Overhauser-Enhanced MRI (O MRI). Nitroxide

  9. 996 RESONANCE November 2013

    Indian Academy of Sciences (India)

    IAS Admin

    996. RESONANCE. November 2013. Page 2. 997. RESONANCE. November 2013. Page 3. 998. RESONANCE. November 2013. Page 4. 999. RESONANCE. November 2013. Page 5. 1000. RESONANCE. November 2013. Page 6. 1001. RESONANCE. November 2013. Page 7. 1002. RESONANCE. November 2013 ...

  10. 817 RESONANCE September 2013

    Indian Academy of Sciences (India)

    IAS Admin

    817. RESONANCE ⎜ September 2013. Page 2. 818. RESONANCE ⎜ September 2013. Page 3. 819. RESONANCE ⎜ September 2013. Page 4. 820. RESONANCE ⎜ September 2013. Page 5. 821. RESONANCE ⎜ September 2013. Page 6. 822. RESONANCE ⎜ September 2013. Page 7. 823. RESONANCE ⎜ September ...

  11. 369 RESONANCE April 2016

    Indian Academy of Sciences (India)

    IAS Admin

    369. RESONANCE ⎜ April 2016. Page 2. 370. RESONANCE ⎜ April 2016. Page 3. 371. RESONANCE ⎜ April 2016. Page 4. 372. RESONANCE ⎜ April 2016. Page 5. 373. RESONANCE ⎜ April 2016. Page 6. 374. RESONANCE ⎜ April 2016. Page 7. 375. RESONANCE ⎜ April 2016.

  12. Parameter dependence of resonant spin torque magnetization reversal

    International Nuclear Information System (INIS)

    Fricke, L.; Serrano-Guisan, S.; Schumacher, H.W.

    2012-01-01

    We numerically study ultra fast resonant spin torque (ST) magnetization reversal in magnetic tunneling junctions (MTJ) driven by current pulses having a direct current (DC) and a resonant alternating current (AC) component. The precessional ST dynamics of the single domain MTJ free layer cell are modeled in the macro spin approximation. The energy efficiency, reversal time, and reversal reliability are investigated under variation of pulse parameters like direct and AC current amplitude, AC frequency and AC phase. We find a range of AC and direct current amplitudes where robust resonant ST reversal is obtained with faster switching time and reduced energy consumption per pulse compared to purely direct current ST reversal. However, for a certain range of AC and direct current amplitudes a strong dependence of the reversal properties on AC frequency and phase is found. Such regions of unreliable reversal must be avoided for ST memory applications.

  13. Parameter dependence of resonant spin torque magnetization reversal

    Science.gov (United States)

    Fricke, L.; Serrano-Guisan, S.; Schumacher, H. W.

    2012-04-01

    We numerically study ultra fast resonant spin torque (ST) magnetization reversal in magnetic tunneling junctions (MTJ) driven by current pulses having a direct current (DC) and a resonant alternating current (AC) component. The precessional ST dynamics of the single domain MTJ free layer cell are modeled in the macro spin approximation. The energy efficiency, reversal time, and reversal reliability are investigated under variation of pulse parameters like direct and AC current amplitude, AC frequency and AC phase. We find a range of AC and direct current amplitudes where robust resonant ST reversal is obtained with faster switching time and reduced energy consumption per pulse compared to purely direct current ST reversal. However, for a certain range of AC and direct current amplitudes a strong dependence of the reversal properties on AC frequency and phase is found. Such regions of unreliable reversal must be avoided for ST memory applications.

  14. Quantum trajectories in elastic atom-surface scattering: threshold and selective adsorption resonances.

    Science.gov (United States)

    Sanz, A S; Miret-Artés, S

    2005-01-01

    The elastic resonant scattering of He atoms off the Cu(117) surface is fully described with the formalism of quantum trajectories provided by Bohmian mechanics. Within this theory of quantum motion, the concept of trapping is widely studied and discussed. Classically, atoms undergo impulsive collisions with the surface, and then the trapped motion takes place covering at least two consecutive unit cells. However, from a Bohmian viewpoint, atom trajectories can smoothly adjust to the equipotential energy surface profile in a sort of sliding motion; thus the trapping process could eventually occur within one single unit cell. In particular, both threshold and selective adsorption resonances are explained by means of this quantum trapping considering different space and time scales. Furthermore, a mapping between each region of the (initial) incoming plane wave and the different parts of the diffraction and resonance patterns can be easily established, an important issue only provided by a quantum trajectory formalism. (c) 2005 American Institute of Physics.

  15. Apodized coupled resonator waveguides.

    Science.gov (United States)

    Capmany, J; Muñoz, P; Domenech, J D; Muriel, M A

    2007-08-06

    In this paper we propose analyse the apodisation or windowing of the coupling coefficients in the unit cells of coupled resonator waveguide devices (CROWs) as a means to reduce the level of secondary sidelobes in the bandpass characteristic of their transfer functions. This technique is regularly employed in the design of digital filters and has been applied as well in the design of other photonic devices such as corrugated waveguide filters and fiber Bragg gratings. The apodisation of both Type-I and Type-II structures is discussed for several windowing functions.

  16. Tri-axial square Helmholtz coil system at the Alibag Magnetic Observatory: upgraded to a magnetic sensor calibration facility

    Science.gov (United States)

    Mahavarkar, Prasanna; John, Jacob; Dhapre, Vijay; Dongre, Varun; Labde, Sachin

    2018-04-01

    A tri-axial square Helmholtz coil system for the study of palaeomagnetic studies, manufactured by GEOFYZIKA (former Czechoslovakia), was successfully commissioned at the Alibag Magnetic Observatory (IAGA code: ABG) in the year 1985. This system was used for a few years, after which the system encountered technical problems with the control unit. Rectification of the unit could not be undertaken, as the information document related to this system was not available, and as a result the system had been lying in an unused state for a long time, until 2015, when the system was recommissioned and upgraded to a test facility for calibrating the magnetometer sensors. We have upgraded the system with a constant current source and a data-logging unit. Both of these units have been designed and developed in the institute laboratory. Also, re-measurements of the existing system have been made thoroughly. The upgraded system is semi-automatic, enabling non-specialists to operate it after a brief period of instruction. This facility is now widely used at the parent institute and external institutions to calibrate magnetometers and it also serves as a national facility. Here the design of this system with the calibration results for the space-borne fluxgate magnetometers is presented.

  17. Tri-axial square Helmholtz coil system at the Alibag Magnetic Observatory: upgraded to a magnetic sensor calibration facility

    Directory of Open Access Journals (Sweden)

    P. Mahavarkar

    2018-04-01

    Full Text Available A tri-axial square Helmholtz coil system for the study of palaeomagnetic studies, manufactured by GEOFYZIKA (former Czechoslovakia, was successfully commissioned at the Alibag Magnetic Observatory (IAGA code: ABG in the year 1985. This system was used for a few years, after which the system encountered technical problems with the control unit. Rectification of the unit could not be undertaken, as the information document related to this system was not available, and as a result the system had been lying in an unused state for a long time, until 2015, when the system was recommissioned and upgraded to a test facility for calibrating the magnetometer sensors. We have upgraded the system with a constant current source and a data-logging unit. Both of these units have been designed and developed in the institute laboratory. Also, re-measurements of the existing system have been made thoroughly. The upgraded system is semi-automatic, enabling non-specialists to operate it after a brief period of instruction. This facility is now widely used at the parent institute and external institutions to calibrate magnetometers and it also serves as a national facility. Here the design of this system with the calibration results for the space-borne fluxgate magnetometers is presented.

  18. Germany: Overview of activities on Neutron Imaging (NI) and Cultural Heritage (CH) studies - Helmholtz-Zentrum Berlin

    International Nuclear Information System (INIS)

    Kardjilov, Nikolay

    2012-01-01

    Neutron imaging is a non-destructive investigation method with a fast growing application field in materials research and fundamental science. The method is used broadly in the cultural heritage research as complementary technique to x-ray imaging. The ability of neutron beam to transmit thick layers of metal and the sensitivity to light elements makes the technique unique for detection of organic substances in metal and stone matrices. The high penetration power of neutrons allows for investigation of samples with real dimensions of about 100 cm3. The neutron imaging in cultural heritage helps to provide information about manufacturing processes and material properties which is very important for further restoration and conservation of the objects. The development of new methods like energy selective imaging and grating interferometry and the application of autoradiography increase the potential of the method for characterization of cultural heritage samples. The neutron tomography instrument CONRAD has been in operation since 2005 at the Hahn-Meitner research reactor at Helmholtz-Zentrum Berlin (HZB). Over the last 5 years, significant development work has been performed to expand the radiographic and tomographic capabilities of the beamline. New techniques have been implemented, including imaging with polarized neutrons, Bragg-edge mapping, high-resolution neutron imaging and grating interferometry. These methods together with the autoradiography have been provided to the user community as tools to help address scientific problems particularly in the field of cultural heritage and palaeontology. Descriptions and parameters of the facilities are given

  19. Modelling of a diode laser with a resonant grating of quantum wells and an external mirror

    International Nuclear Information System (INIS)

    Vysotskii, D V; Elkin, N N; Napartovich, A P; Kozlovskii, Vladimir I; Lavrushin, B M

    2011-01-01

    A three-dimensional numerical model of a diode laser with a resonant grating of quantum wells (QWs) and an external mirror is developed and used to calculate diode laser pulses that are long compared to the time of reaching a stationary regime and are short enough to neglect heating of the medium. The consistent solutions of the Helmholtz field equation and the system of diffusion equations for inversion in each QW are found. A source of charge carriers can be both an electron beam and a pump laser beam. The calculations yielded the longitudinal and radial profiles of the generated field, as well as its wavelength and power. The effective threshold pump current is determined. In the created iteration algorithm, the calculation time linearly increases with the number of QWs, which allows one to find the characteristics of lasers with a large number of QWs. The output powers and beam divergence angles of a cylindrical laser are calculated for different cavity lengths and pump spot radii. After calculating the fundamental mode characteristics, high-order modes were additionally calculated on the background of the frozen carrier distributions in the QW grating. It is shown that all the competing modes remain below the excitation threshold for the pump powers used in the experiment. The calculated and experimental data for the case of pumping by a nanosecond electron beam are qualitatively compared.

  20. Solution of the Helmholtz-Poincare Wave Equation using the coupled boundary integral equations and optimal surface eigenfunctions

    International Nuclear Information System (INIS)

    Werby, M.F.; Broadhead, M.K.; Strayer, M.R.; Bottcher, C.

    1992-01-01

    The Helmholtz-Poincarf Wave Equation (H-PWE) arises in many areas of classical wave scattering theory. In particular it can be found for the cases of acoustical scattering from submerged bounded objects and electromagnetic scattering from objects. The extended boundary integral equations (EBIE) method is derived from considering both the exterior and interior solutions of the H-PWECs. This coupled set of expressions has the advantage of not only offering a prescription for obtaining a solution for the exterior scattering problem, but it also obviates the problem of irregular values corresponding to fictitious interior eigenvalues. Once the coupled equations are derived, they can be obtained in matrix form by expanding all relevant terms in partial wave expansions, including a bi-orthogonal expansion of the Green's function. However some freedom in the choice of the surface expansion is available since the unknown surface quantities may be expanded in a variety of ways so long as closure is obtained. Out of many possible choices, we develop an optimal method to obtain such expansions which is based on the optimum eigenfunctions related to the surface of the object. In effect, we convert part of the problem (that associated with the Fredholms integral equation of the first kind) an eigenvalue problem of a related Hermitian operator. The methodology will be explained in detail and examples will be presented

  1. Diffusion in a tokamak with helical magnetic cells

    International Nuclear Information System (INIS)

    Wakatani, Masahiro

    1975-05-01

    In a tokamak with helical magnetic cells produced by a resonant helical magnetic field, diffusion in the collisional regime is studied. The diffusion coefficient is greatly enhanced near the resonant surface even for a weak helical magnetic field. A theoretical model for disruptive instabilities based on the enhanced transport due to helical magnetic cells is discussed. This may explain experiments of the tokamak with resonant helical fields qualitatively. (author)

  2. Snake resonances

    International Nuclear Information System (INIS)

    Tepikian, S.

    1988-01-01

    Siberian Snakes provide a practical means of obtaining polarized proton beams in large accelerators. The effect of snakes can be understood by studying the dynamics of spin precession in an accelerator with snakes and a single spin resonance. This leads to a new class of energy independent spin depolarizing resonances, called snake resonances. In designing a large accelerator with snakes to preserve the spin polarization, there is an added constraint on the choice of the vertical betatron tune due to the snake resonances. 11 refs., 4 figs

  3. Multimodal Theranostic Nanoformulations Permit Magnetic Resonance Bioimaging of Antiretroviral Drug Particle Tissue-Cell Biodistribution

    Science.gov (United States)

    Kevadiya, Bhavesh D.; Woldstad, Christopher; Ottemann, Brendan M.; Dash, Prasanta; Sajja, Balasrinivasa R.; Lamberty, Benjamin; Morsey, Brenda; Kocher, Ted; Dutta, Rinku; Bade, Aditya N.; Liu, Yutong; Callen, Shannon E.; Fox, Howard S.; Byrareddy, Siddappa N.; McMillan, JoEllyn M.; Bronich, Tatiana K.; Edagwa, Benson J.; Boska, Michael D.; Gendelman, Howard E.

    2018-01-01

    RATIONALE: Long-acting slow effective release antiretroviral therapy (LASER ART) was developed to improve patient regimen adherence, prevent new infections, and facilitate drug delivery to human immunodeficiency virus cell and tissue reservoirs. In an effort to facilitate LASER ART development, “multimodal imaging theranostic nanoprobes” were created. These allow combined bioimaging, drug pharmacokinetics and tissue biodistribution tests in animal models. METHODS: Europium (Eu3+)- doped cobalt ferrite (CF) dolutegravir (DTG)- loaded (EuCF-DTG) nanoparticles were synthesized then fully characterized based on their size, shape and stability. These were then used as platforms for nanoformulated drug biodistribution. RESULTS: Folic acid (FA) decoration of EuCF-DTG (FA-EuCF-DTG) nanoparticles facilitated macrophage targeting and sped drug entry across cell barriers. Macrophage uptake was higher for FA-EuCF-DTG than EuCF-DTG nanoparticles with relaxivities of r2 = 546 mM-1s-1 and r2 = 564 mM-1s-1 in saline, and r2 = 850 mM-1s-1 and r2 = 876 mM-1s-1 in cells, respectively. The values were ten or more times higher than what was observed for ultrasmall superparamagnetic iron oxide particles (r2 = 31.15 mM-1s-1 in saline) using identical iron concentrations. Drug particles were detected in macrophage Rab compartments by dual fluorescence labeling. Replicate particles elicited sustained antiretroviral responses. After parenteral injection of FA-EuCF-DTG and EuCF-DTG into rats and rhesus macaques, drug, iron and cobalt levels, measured by LC-MS/MS, magnetic resonance imaging, and ICP-MS were coordinate. CONCLUSION: We posit that these theranostic nanoprobes can assess LASER ART drug delivery and be used as part of a precision nanomedicine therapeutic strategy. PMID:29290806

  4. Diffusion magnetic resonance imaging of breast lesions: Initial ...

    African Journals Online (AJOL)

    Hebatallah Hassan Mamdouh Hassan

    2013-03-31

    Mar 31, 2013 ... breast cancer.2 Additional lesions seen by MRI that are not visible on ... characterization of lesions as benign or malignant on the basis ... lular density associated with numerous intact cell ..... ence for ADC values between the two MRI devices, the lesions .... Magnetic resonance imaging of brain and spine.

  5. Far from Equilibrium Percolation, Stochastic and Shape Resonances in the Physics of Life

    Directory of Open Access Journals (Sweden)

    Antonio Bianconi

    2011-10-01

    Full Text Available Key physical concepts, relevant for the cross-fertilization between condensed matter physics and the physics of life seen as a collective phenomenon in a system out-of-equilibrium, are discussed. The onset of life can be driven by: (a the critical fluctuations at the protonic percolation threshold in membrane transport; (b the stochastic resonance in biological systems, a mechanism that can exploit external and self-generated noise in order to gain efficiency in signal processing; and (c the shape resonance (or Fano resonance or Feshbach resonance in the association and dissociation processes of bio-molecules (a quantum mechanism that could play a key role to establish a macroscopic quantum coherence in the cell.

  6. 2D and 3D Modeling Efforts in Fuel Film Cooling of Liquid Rocket Engines (Conference Paper with Briefing Charts)

    Science.gov (United States)

    2017-01-12

    to determine what parameters drive unsteadiness in fuel films, and how these parameters affect wall temperature profiles. Parametric studies performed...temperature profiles. Parametric studies performed in 2D suggest that a Helmholtz resonator exists for simple slot geometries. Frequencies in 3D were...effect on film cooling effectiveness. In general, the heat flux exhibits complex trends and did not scale well with chamber pressure. ∗Aerospace

  7. Imaging of activated caspase-3 in living cell by fluorescence resonance energy transfer during photosensitization-induced apoptosis

    Science.gov (United States)

    Wu, Yunxia; Xing, Da; Chen, Qun; Tang, Yonghong

    2005-01-01

    Photodynamic therapy (PDT) is a novel and promising cancer treatment that employs a combination of a photosensitizing chemical and visible light, induces apoptosis in cell, and activation of caspase-3 is considered to be the final step in many apoptosis pathways. The changes of caspase-3 activation in cell during TNFα- and photodynamic therapy-induced apoptosis was measured by fluorescence resonance energy transfer (FRET) analysis. FRET probe consisting of fusions of an enhanced cyan fluorescent protein (ECFP), Venus and a linker peptide containing the caspase-3 cleavage sequence DEVD was utilized. Therefore, activated caspase-3 cleaved the linker peptide of FRET probe and disrupted the FRET signal. Human lung adenocarcinoma cell line (ASTC-a-1) were stably transfected with the plasmid (ECFP-DEVD-Venus) and then were treated by TNF-α and PDT, respectively. Experimental results indicated that caspase-3 activation resulted in cleavage of linker peptide and subsequent disruption of the FRET signal during TNFα- and photodynamic therapy-induced apoptosis, and that the activation of caspase-3 induced by photodynamic therapy was faster than that induce by TNF-α. The study supports that using FRET technique and different recombinant substrates as FRET probes could be used to detect the process of PDT-induced apoptosis and provide a new means to investigate apoptotic mechanism of PDT.

  8. Noninvasive imaging of protein-protein interactions from live cells and living subjects using bioluminescence resonance energy transfer.

    Science.gov (United States)

    De, Abhijit; Gambhir, Sanjiv Sam

    2005-12-01

    This study demonstrates a significant advancement of imaging of a distance-dependent physical process, known as the bioluminescent resonance energy transfer (BRET2) signal in living subjects, by using a cooled charge-coupled device (CCD) camera. A CCD camera-based spectral imaging strategy enables simultaneous visualization and quantitation of BRET signal from live cells and cells implanted in living mice. We used the BRET2 system, which utilizes Renilla luciferase (hRluc) protein and its substrate DeepBlueC (DBC) as an energy donor and a mutant green fluorescent protein (GFP2) as the acceptor. To accomplish this objective in this proof-of-principle study, the donor and acceptor proteins were fused to FKBP12 and FRB, respectively, which are known to interact only in the presence of the small molecule mediator rapamycin. Mammalian cells expressing these fusion constructs were imaged using a cooled-CCD camera either directly from culture dishes or by implanting them into mice. By comparing the emission photon yields in the presence and absence of rapamycin, the specific BRET signal was determined. The CCD imaging approach of BRET signal is particularly appealing due to its capacity to seamlessly bridge the gap between in vitro and in vivo studies. This work validates BRET as a powerful tool for interrogating and observing protein-protein interactions directly at limited depths in living mice.

  9. 1004 RESONANCE November 2013

    Indian Academy of Sciences (India)

    IAS Admin

    1004. RESONANCE │ November 2013. Page 2. 1005. RESONANCE │ November 2013. Page 3. 1006. RESONANCE │ November 2013. Page 4. 1007. RESONANCE │ November 2013. Page 5. 1008. RESONANCE │ November 2013. Page 6. 1009. RESONANCE │ November 2013. Page 7. 1010. RESONANCE ...

  10. Synchrobetatron resonances

    International Nuclear Information System (INIS)

    1977-03-01

    At the 1975 Particle Accelerator Conference it was reported that a class of resonances were observed in SPEAR II that had not appeared before in SPEAR I. While the existence of sideband resonances of the main betatron oscillation frequencies has been previously observed and analyzed, the resonances observed in SPEAR do not appear to be of the same variety. Experiments were performed at SPEAR to identify the mechanism believed to be the most likely explanation. Some of the current experimental knowledge and theoretical views on the source of these resonances are presented

  11. Using the minimum principle for the Helmholtz free energy in the analysis of the equilibria of a van der Waals fluid

    International Nuclear Information System (INIS)

    Ascoli, Sergio; Malvestuto, Vincenzo

    2004-01-01

    For a fluid system, obeying a state equation of the van der Waals type, the gas and the liquid phases can coexist in equilibrium, at a given temperature, only if the volume of the system is kept fixed. Thus, in order to study the two-phase equilibria of a fluid system, it seemed quite natural to choose the molar volume as the independent variable, and, consequently, the Helmholtz free energy as the proper thermodynamic potential for the application of the minimum principle. Specific computations are here carried out for a single van der Waals fluid, namely, pure water at 300 0 C. As a result, the present treatment indicates a simple and effective way to identify the whole range of molar volumes where the equilibrium preferred by the system is a two-phase equilibrium. This range results to be wider than the interval of strict instability of the van der Waals isotherm. Finally, it is pointed out that all the results, obtained here for the van der Waals state equation, can be extended to all the state equations of the same type

  12. Pulsed power magnet technology for laser particle acceleration and laser plasma physics - a survey of developments at Helmholtz-Zentrum Dresden-Rossendorf

    Energy Technology Data Exchange (ETDEWEB)

    Kroll, Florian; Joost, Martin [Helmholtz-Zentrum Dresden-Rossendorf (Germany); TU Dresden (Germany); Burris-Mog, Trevor; Herrmannsdoerfer, Thomas; Kraft, Stephan; Masood, Umar; Schlenvoigt, Hans-Peter; Sobiella, Manfred; Wustmann, Bernd; Zherlitsyn, Sergei; Cowan, Thomas; Schramm, Ulrich [Helmholtz-Zentrum Dresden-Rossendorf (Germany)

    2013-07-01

    Since the mid-1950s, pulsed high-field magnets have become a common, versatile research tool with application mostly in solid state physics and material research. Recently developed pulsed power magnet technology, specifically designed to meet the demands of laser acceleration and laser plasma experiments, open up new research opportunities: We present a pulsed air core solenoid (up to 20 T) for effective collection and focusing of laser accelerated particles. It could function as a crucial part of a compact, laser-based ion source (pursued by the LIGHT collaboration) or of beam guidance systems. Furthermore, the poster shows a split pair coil, utterly compact and with optical access in between the coil pairs and on axis, to study laser-driven plasma expansion under high magnetic fields (30 T). To power such devices, portable capacitor-based pulse generators have been developed at Helmholtz-Zentrum Dresden-Rossendorf. We present first results of the functional testing of our third-generation pulse generator. Looking forward, we outline a concept for a medical gantry based on pulsed high field beam optics.

  13. Synthesis and systematic evaluation of dark resonance energy transfer (DRET)-based library and its application in cell imaging.

    Science.gov (United States)

    Su, Dongdong; Teoh, Chai Lean; Kang, Nam-Young; Yu, Xiaotong; Sahu, Srikanta; Chang, Young-Tae

    2015-03-01

    In this paper, we report a new strategy for constructing a dye library with large Stokes shifts. By coupling a dark donor with BODIPY acceptors of tunable high quantum yield, a novel dark resonance energy transfer (DRET)-based library, named BNM, has been synthesized. Upon excitation of the dark donor (BDN) at 490 nm, the absorbed energy is transferred to the acceptor (BDM) with high efficiency, which was tunable in a broad range from 557 nm to 716 nm, with a high quantum yield of up to 0.8. It is noteworthy to mention that the majority of the non-radiative energy loss of the donor was converted into the acceptor's fluorescence output with a minimum leak of donor emission. Fluorescence imaging tested in live cells showed that the BNM compounds are cell-permeable and can also be employed for live-cell imaging. This is a new library which can be excited through a dark donor allowing for strong fluorescence emission in a wide range of wavelengths. Thus, the BNM library is well suited for high-throughput screening or multiplex experiments in biological applications by using a single laser excitation source. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Theoretical study of platonic crystals with periodically structured N-beam resonators

    Science.gov (United States)

    Gao, Penglin; Climente, Alfonso; Sánchez-Dehesa, José; Wu, Linzhi

    2018-03-01

    A multiple scattering theory is applied to study the properties of flexural waves propagating in a plate with periodically structured N-beam resonators. Each resonator consists of a circular hole containing an inner disk connected to background plate with N rectangular beams. The Bloch theorem is employed to obtain the band structure of a two-dimensional lattice containing a single resonator per unit cell. Also, a numerical algorithm has been developed to get the transmittance through resonator slabs infinitely long in the direction perpendicular to the incident wave. For the numerical validation, a square lattice of 2-beam resonators has been comprehensively analyzed. Its band structure exhibits several flat bands, indicating the existence of local resonances embedded in the structure. Particularly, the one featured as the fundamental mode of the inner disk opens a bandgap at low frequencies. This mode has been fully described in terms of a simple spring-mass model. As a practical application of the results obtained, a homogenization approach has been employed to design a focusing lens for flexural waves, where the index gradient is obtained by adjusting the orientation of the resonators beams. Numerical experiments performed within the framework of a three-dimensional finite element method have been employed to discuss the accuracy of the models described here.

  15. A high-throughput fluorescence resonance energy transfer (FRET)-based endothelial cell apoptosis assay and its application for screening vascular disrupting agents

    International Nuclear Information System (INIS)

    Zhu, Xiaoming; Fu, Afu; Luo, Kathy Qian

    2012-01-01

    Highlights: ► An endothelial cell apoptosis assay using FRET-based biosensor was developed. ► The fluorescence of the cells changed from green to blue during apoptosis. ► This method was developed into a high-throughput assay in 96-well plates. ► This assay was applied to screen vascular disrupting agents. -- Abstract: In this study, we developed a high-throughput endothelial cell apoptosis assay using a fluorescence resonance energy transfer (FRET)-based biosensor. After exposure to apoptotic inducer UV-irradiation or anticancer drugs such as paclitaxel, the fluorescence of the cells changed from green to blue. We developed this method into a high-throughput assay in 96-well plates by measuring the emission ratio of yellow fluorescent protein (YFP) to cyan fluorescent protein (CFP) to monitor the activation of a key protease, caspase-3, during apoptosis. The Z′ factor for this assay was above 0.5 which indicates that this assay is suitable for a high-throughput analysis. Finally, we applied this functional high-throughput assay for screening vascular disrupting agents (VDA) which could induce endothelial cell apoptosis from our in-house compounds library and dioscin was identified as a hit. As this assay allows real time and sensitive detection of cell apoptosis, it will be a useful tool for monitoring endothelial cell apoptosis in living cell situation and for identifying new VDA candidates via a high-throughput screening.

  16. Ultra-narrow band perfect absorbers based on Fano resonance in MIM metamaterials

    Science.gov (United States)

    Zhang, Ming; Fang, Jiawen; Zhang, Fei; Chen, Junyan; Yu, Honglin

    2017-12-01

    Metallic nanostructures have attracted numerous attentions in the past decades due to their attractive plasmonic properties. Resonant plasmonic perfect absorbers have promising applications in a wide range of technologies including photothermal therapy, thermophotovoltaics, heat-assisted magnetic recording and biosensing. However, it remains to be a great challenge to achieve ultra-narrow band in near-infrared band with plasmonic materials due to the large optical losses in metals. In this letter, we introduced Fano resonance in MIM metamaterials composed of an asymmetry double elliptic cylinders (ADEC), which can achieve ultra-narrow band perfect absorbers. In theoretical calculations, we observed an ultranarrow band resonant absorption peak with the full width at half maximum (FWHM) of 8 nm and absorption amplitude exceeding 99% at 930 nm. Moreover, we demonstrate that the absorption increases with the increase of asymmetry and the absorption resonant wavelength can be tuned by changing the size and arrangement of the unit cell. The asymmetry metallic nanostructure also exhibit a higher refractive sensitivity as large as 503 nm/RIU with high figure of merit of 63, which is promising for high sensitive sensors. Results of this work are desirable for various potential applications in micro-technological structures such as biological sensors, narrowband emission, photodetectors and solar thermophotovoltaic (STPV) cells.

  17. A Crossed Pack-to-Cell Equalizer Based on Quasi-Resonant LC Converter with Adaptive Fuzzy Logic Equalization Control for Series-connected Lithium-Ion Battery Strings

    DEFF Research Database (Denmark)

    Shang, Yunlong; Zhang, Chenghui; Cui, Naxin

    2015-01-01

    The equalization speed, efficiency, and control are the key issues of battery equalization. This paper proposes a crossed pack-to-cell equalizer based on quasi-resonant LC converter (QRLCC). The battery string is divided into M modules, and each module consists of N series-connected cells....... The energy can be transferred directly from a battery module to the lowest voltage cell (LVC) in the next adjacent module, which results in an enhancement of equalization efficiency and current. The QRLCC is employed to gain zero-current switching (ZCS), leading to a reduction of power losses......-equalization. A prototype with eight lithiumion battery cells is implemented. Experimental results show the proposed scheme exhibits outstanding balancing performance, and the equalization efficiency is higher than 98%. The proposed AFLC algorithm abridges the total equalization time about 47%, and reduces the switching...

  18. Anti-HER2 immunoliposomes for selective delivery of electron paramagnetic resonance imaging probes to HER2-overexpressing breast tumor cells

    Science.gov (United States)

    Burks, Scott R.; Macedo, Luciana F.; Barth, Eugene D.; Tkaczuk, Katherine H.; Martin, Stuart S.; Rosen, Gerald M.; Halpern, Howard J.; Brodie, Angela M.

    2014-01-01

    Electron paramagnetic resonance (EPR) imaging is an emerging modality that can detect and localize paramagnetic molecular probes (so-called spin probes) in vivo. We previously demonstrated that nitroxide spin probes can be encapsulated in liposomes at concentrations exceeding 100 mM, at which nitroxides exhibit a concentration-dependent quenching of their EPR signal that is analogous to the self-quenching of fluorescent molecules. Therefore, intact liposomes encapsulating high concentrations of nitroxides exhibit greatly attenuated EPR spectral signals, and endocytosis of such liposomes represents a cell-activated contrast-generating mechanism. After endocytosis, the encapsulated nitroxide is liberated and becomes greatly diluted in the intracellular milieu. This dequenches the nitroxides to generate a robust intracellular EPR signal. It is therefore possible to deliver a high concentration of nitroxides to cells while minimizing background signal from unendocytosed liposomes. We report here that intracellular EPR signal can be selectively generated in a specific cell type by exploiting its expression of Human Epidermal Growth Factor Receptor 2 (HER2). When targeted by anti-HER2 immunoliposomes encapsulating quenched nitroxides, Hc7 cells, which are novel HER2-overexpressing cells derived from the MCF7 breast tumor cell line, endocytose the liposomes copiously, in contrast to the parent MCF7 cells or control CV1 cells, which do not express HER2. HER2-dependent liposomal delivery enables Hc7 cells to accumulate 750 μM nitroxide intracellularly. Through the use of phantom models, we verify that this concentration of nitroxides is more than sufficient for EPR imaging, thus laying the foundation for using EPR imaging to visualize HER2-overexpressing Hc7 tumors in animals. PMID:20066490

  19. Even order snake resonances

    International Nuclear Information System (INIS)

    Lee, S.Y.

    1993-01-01

    We found that the perturbed spin tune due to the imperfection resonance plays an important role in beam depolarization at snake resonances. We also found that even order snake resonances exist in the overlapping intrinsic and imperfection resonances. Due to the perturbed spin tune shift of imperfection resonances, each snake resonance splits into two

  20. Acoustic resonance in MEMS scale cylindrical tubes with side branches

    Science.gov (United States)

    Schill, John F.; Holthoff, Ellen L.; Pellegrino, Paul M.; Marcus, Logan S.

    2014-05-01

    Photoacoustic spectroscopy (PAS) is a useful monitoring technique that is well suited for trace gas detection. This method routinely exhibits detection limits at the parts-per-million (ppm) or parts-per-billion (ppb) level for gaseous samples. PAS also possesses favorable detection characteristics when the system dimensions are scaled to a microelectromechanical system (MEMS) design. One of the central issues related to sensor miniaturization is optimization of the photoacoustic cell geometry, especially in relationship to high acoustical amplification and reduced system noise. Previous work relied on a multiphysics approach to analyze the resonance structures of the MEMS scale photo acoustic cell. This technique was unable to provide an accurate model of the acoustic structure. In this paper we describe a method that relies on techniques developed from musical instrument theory and electronic transmission line matrix methods to describe cylindrical acoustic resonant cells with side branches of various configurations. Experimental results are presented that demonstrate the ease and accuracy of this method. All experimental results were within 2% of those predicted by this theory.

  1. Sample-size resonance, ferromagnetic resonance and magneto-permittivity resonance in multiferroic nano-BiFeO3/paraffin composites at room temperature

    International Nuclear Information System (INIS)

    Wang, Lei; Li, Zhenyu; Jiang, Jia; An, Taiyu; Qin, Hongwei; Hu, Jifan

    2017-01-01

    In the present work, we demonstrate that ferromagnetic resonance and magneto-permittivity resonance can be observed in appropriate microwave frequencies at room temperature for multiferroic nano-BiFeO 3 /paraffin composite sample with an appropriate sample-thickness (such as 2 mm). Ferromagnetic resonance originates from the room-temperature weak ferromagnetism of nano-BiFeO 3 . The observed magneto-permittivity resonance in multiferroic nano-BiFeO 3 is connected with the dynamic magnetoelectric coupling through Dzyaloshinskii–Moriya (DM) magnetoelectric interaction or the combination of magnetostriction and piezoelectric effects. In addition, we experimentally observed the resonance of negative imaginary permeability for nano BiFeO 3 /paraffin toroidal samples with longer sample thicknesses D=3.7 and 4.9 mm. Such resonance of negative imaginary permeability belongs to sample-size resonance. - Highlights: • Nano-BiFeO 3 /paraffin composite shows a ferromagnetic resonance. • Nano-BiFeO 3 /paraffin composite shows a magneto-permittivity resonance. • Resonance of negative imaginary permeability in BiFeO 3 is a sample-size resonance. • Nano-BiFeO 3 /paraffin composite with large thickness shows a sample-size resonance.

  2. An improved prism for use in laser resonators

    Science.gov (United States)

    Richards, J.

    1981-08-01

    The use of compound total internal reflection prisms rather than Porro prisms in polarisation coupled lasers is proposed. Performance advantages resulting from the use of these prisms include higher output without the need to bias the Pockels cell, ability to give a larger range of output coupling and independence of performance on the refractive index of the prism. In conventional Q-switched lasers the use of the prism at the Pockels cell end of the resonator instead of the usual 100% reflecting mirror also leads to some advantages including better hold-off, elimination of the need to bias the Pockels cell and insensitivity in one plane to angular misalignment.

  3. Amplitude saturation of MEMS resonators explained by autoparametric resonance

    International Nuclear Information System (INIS)

    Van der Avoort, C; Bontemps, J J M; Steeneken, P G; Le Phan, K; Van Beek, J T M; Van der Hout, R; Hulshof, J; Fey, R H B

    2010-01-01

    This paper describes a phenomenon that limits the power handling of MEMS resonators. It is observed that above a certain driving level, the resonance amplitude becomes independent of the driving level. In contrast to previous studies of power handling of MEMS resonators, it is found that this amplitude saturation cannot be explained by nonlinear terms in the spring constant or electrostatic force. Instead we show that the amplitude in our experiments is limited by nonlinear terms in the equation of motion which couple the in-plane length-extensional resonance mode to one or more out-of-plane (OOP) bending modes. We present experimental evidence for the autoparametric excitation of these OOP modes using a vibrometer. The measurements are compared to a model that can be used to predict a power-handling limit for MEMS resonators

  4. Amplitude saturation of MEMS resonators explained by autoparametric resonance

    Energy Technology Data Exchange (ETDEWEB)

    Van der Avoort, C; Bontemps, J J M; Steeneken, P G; Le Phan, K; Van Beek, J T M [NXP Research, Eindhoven (Netherlands); Van der Hout, R; Hulshof, J [Department of Mathematics, VU University—Faculty of Sciences, De Boelelaan 1081a, 1081 HV Amsterdam (Netherlands); Fey, R H B, E-mail: cas.van.der.avoort@nxp.com [Department of Mechanical Engineering, Eindhoven University of Technology, PO Box 513, 5600 MB, Eindhoven (Netherlands)

    2010-10-15

    This paper describes a phenomenon that limits the power handling of MEMS resonators. It is observed that above a certain driving level, the resonance amplitude becomes independent of the driving level. In contrast to previous studies of power handling of MEMS resonators, it is found that this amplitude saturation cannot be explained by nonlinear terms in the spring constant or electrostatic force. Instead we show that the amplitude in our experiments is limited by nonlinear terms in the equation of motion which couple the in-plane length-extensional resonance mode to one or more out-of-plane (OOP) bending modes. We present experimental evidence for the autoparametric excitation of these OOP modes using a vibrometer. The measurements are compared to a model that can be used to predict a power-handling limit for MEMS resonators.

  5. Experimental results of high power dual frequency resonant magnet excitation at TRIUMF

    International Nuclear Information System (INIS)

    Reiniger, K.W.; Heritier, G.

    1988-06-01

    We present some results of duel frequency resonant magnet excitation at full power using the old NINA synchrotron dipoles. These tests will simulate a typical resonant cell as proposed for the accelerating rings of the TRIUMF KAON Factory. These test have two main purposes: to verify circuit parameters and component ratings for the dual frequency resonant power supply system; and to measure directly electrical losses in a transverse magnet field, such as eddy current losses in magnet conductors, vacuum tubes and core losses in laminations. These data will be required for the detailed design of the accelerator system components. (Author) (Ref., 9 figs., tab.)

  6. Quantification of plant cell coupling with live-cell microscopy

    DEFF Research Database (Denmark)

    Liesche, Johannes; Schulz, Alexander

    2015-01-01

    by confocal microscopy, loaded tracer is activated by UV illumination in a target cell and its spread to neighboring cells monitored. When combined with high-speed acquisition by resonant scanning or spinning disc confocal microscopy, the high signal-to-noise ratio of photoactivation allows collection...

  7. Simultaneous electrical and mechanical resonance drive for large signal amplification of micro resonators

    KAUST Repository

    Hasan, M. H.

    2018-01-12

    Achieving large signal-noise ratio using low levels of excitation signal is key requirement for practical applications of micro and nano electromechanical resonators. In this work, we introduce the double electromechanical resonance drive concept to achieve an order-of-magnitude dynamic signal amplification in micro resonators. The concept relies on simultaneously activating the micro-resonator mechanical and electrical resonance frequencies. We report an input voltage amplification up to 15 times for a micro-resonator when its electrical resonance is tuned to match the mechanical resonance that leads to dynamic signal amplification in air (Quality factor enhancement). Furthermore, using a multi-frequency excitation technique, input voltage and vibrational amplification of up to 30 times were shown for the same micro-resonator while relaxing the need to match its mechanical and electrical resonances.

  8. Simultaneous electrical and mechanical resonance drive for large signal amplification of micro resonators

    KAUST Repository

    Hasan, M. H.; Alsaleem, F. M.; Jaber, Nizar; Hafiz, Md Abdullah Al; Younis, Mohammad I.

    2018-01-01

    Achieving large signal-noise ratio using low levels of excitation signal is key requirement for practical applications of micro and nano electromechanical resonators. In this work, we introduce the double electromechanical resonance drive concept to achieve an order-of-magnitude dynamic signal amplification in micro resonators. The concept relies on simultaneously activating the micro-resonator mechanical and electrical resonance frequencies. We report an input voltage amplification up to 15 times for a micro-resonator when its electrical resonance is tuned to match the mechanical resonance that leads to dynamic signal amplification in air (Quality factor enhancement). Furthermore, using a multi-frequency excitation technique, input voltage and vibrational amplification of up to 30 times were shown for the same micro-resonator while relaxing the need to match its mechanical and electrical resonances.

  9. Investigation of Kelvin-Helmholtz Instability in the boundary layer using Doppler lidar and radiosonde data

    Science.gov (United States)

    Das, Subrata Kumar; Das, Siddarth Shankar; Saha, Korak; Murali Krishna, U. V.; Dani, K. K.

    2018-04-01

    Characteristics of Kelvin Helmholtz Instability (KHI) using Doppler wind lidar observation have rarely been reported during the Indian summer monsoon season. In this paper, we present a case study of KHI near planetary boundary layer using Doppler wind lidar and radiosonde measurements at Mahabubnagar, a tropical Indian station. The data was collected during the Integrated Ground Observation Campaign (June-October 2011) under the Cloud Aerosol Interaction and Precipitation Enhancement EXperiment-2011. The continuous wind lidar observation during 10-16 August 2011 shows there is an increase in carrier-to-noise ratio values near planetary boundary layer from 03:00 to 11:00 LT on 13 August; reveals the formation of KHI. There is a strong power bursts pattern corresponding to high turbulence characteristics in the early half of the day. The KHI temporal evolution from initial to dissipating stage is observed with clear variation in the carrier-to-noise ratio values. The observed KHI billows are in the height between 600 and 1200 m and lasted for about 7.5 h. The vertical velocity from Doppler lidar measurement shows the presence of updrafts after breaking of KHI in the boundary layer. The presence of strong wind shear, high stability parameter, low Richardson number and high relative humidity during the enhanced carrier-to-noise ratio period indicates the ideal condition for the formation and persistence of this dynamic instability. A typical characteristic of trapped humidity above the KHI billows suggest the presence of strong inversion. A wavelet analysis of 3-dimensional wind components show dominant periodicity of 45-65 min and the periodicity in vertical wind is more prominent.

  10. Erbium-doped fiber ring resonator for resonant fiber optical gyro applications

    Science.gov (United States)

    Li, Chunming; Zhao, Rui; Tang, Jun; Xia, Meijing; Guo, Huiting; Xie, Chengfeng; Wang, Lei; Liu, Jun

    2018-04-01

    This paper reports a fiber ring resonator with erbium-doped fiber (EDF) for resonant fiber optical gyro (RFOG). To analyze compensation mechanism of the EDF on resonator, a mathematical model of the erbium-doped fiber ring resonator (EDFRR) is established based on Jones matrix to be followed by the design and fabrication of a tunable EDFRR. The performances of the fabricated EDFRR were measured and the experimental Q-factor of 2 . 47 × 108 and resonant depth of 109% were acquired separately. Compared with the resonator without the EDF, the resonant depth and Q-factor of the proposed device are increased by 2.5 times and 14 times, respectively. A potential optimum shot noise limited resolution of 0 . 042∘ / h can be obtained for the RFOG, which is promising for low-cost and high precise detection.

  11. Quantum mechanical resonances

    International Nuclear Information System (INIS)

    Cisneros S, A.; McIntosh, H.V.

    1982-01-01

    A discussion of the nature of quantum mechanical resonances is presented from the point of view of the spectral theory of operators. In the case of Bohr-Feshbach resonances, graphs are presented to illustrate the theory showing the decay of a doubly excited metastable state and the excitation of the resonance by an incident particle with proper energy. A characterization of resonances is given as well as a procedure to determine widths using the spectral density function. A sufficient condition is given for the validity of the Breit-Wigner formula for Bohr-Feshbach resonances. (author)

  12. Fabrication of Terahertz Wave Resonators with Alumina Diamond Photonic Crystals for Frequency Amplification in Water Solvents

    International Nuclear Information System (INIS)

    Ohta, N; Niki, T; Kirihara, S

    2011-01-01

    Terahertz wave resonators composed of alumina photonic crystals with diamond lattice structures were designed and fabricated by using micro stereolithography. These three dimensional periodic structures can reflect perfectly electromagnetic waves through Bragg diffraction. A micro glass cell including water solutions was put between the photonic crystals as a novel resonance sensor with terahertz frequency range. The localized and amplified waves in the resonators were measured by a spectroscopy, and visualized by theoretical simulations.

  13. 3C-SiC microdisk mechanical resonators with multimode resonances at radio frequencies

    Science.gov (United States)

    Lee, Jaesung; Zamani, Hamidrera; Rajgopal, Srihari; Zorman, Christian A.; X-L Feng, Philip

    2017-07-01

    We report on the design, modeling, fabrication and measurement of single-crystal 3C-silicon carbide (SiC) microdisk mechanical resonators with multimode resonances operating at radio frequencies (RF). These microdisk resonators (center-clamped on a vertical stem pedestal) offer multiple flexural-mode resonances with frequencies dependent on both disk and anchor dimensions. The resonators are made using a novel fabrication method comprised of focused ion beam nanomachining and hydroflouic : nitric : acetic (HNA) acid etching. Resonance peaks (in the frequency spectrum) are detected through laser-interferometry measurements. Resonators with different dimensions are tested, and multimode resonances, mode splitting, energy dissipation (in the form of quality factor measurement) are investigated. Further, we demonstrate a feedback oscillator based on a passive 3C-SiC resonator. This investigation provides important guidelines for microdisk resonator development, ranging from an analytical prediction of frequency scaling law to fabrication, suggesting RF microdisk resonators can be good candidates for future sensing applications in harsh environments.

  14. Nonlinear resonances

    CERN Document Server

    Rajasekar, Shanmuganathan

    2016-01-01

    This introductory text presents the basic aspects and most important features of various types of resonances and anti-resonances in dynamical systems. In particular, for each resonance, it covers the theoretical concepts, illustrates them with case studies, and reviews the available information on mechanisms, characterization, numerical simulations, experimental realizations, possible quantum analogues, applications and significant advances made over the years. Resonances are one of the most fundamental phenomena exhibited by nonlinear systems and refer to specific realizations of maximum response of a system due to the ability of that system to store and transfer energy received from an external forcing source. Resonances are of particular importance in physical, engineering and biological systems - they can prove to be advantageous in many applications, while leading to instability and even disasters in others. The book is self-contained, providing the details of mathematical derivations and techniques invo...

  15. Non-invasive tracking of human haemopoietic CD34{sup +} stem cells in vivo in immunodeficient mice by using magnetic resonance imaging

    Energy Technology Data Exchange (ETDEWEB)

    Niemeyer, Markus; Jacobs, Volker R.; Timmer, Sebastian; Kiechle, Marion [Technische Universitaet Muenchen, Department of Gynaecology, Klinikum rechts der Isar, Munich (Germany); Oostendorp, Robert A.J.; Hippauf, Sandra; Bekker-Ruz, Viktoria [Technische Universitaet Muenchen, Department of Oncology, Klinikum rechts der Isar, Munich (Germany); Kremer, Markus [Technische Universitaet Muenchen, Department of Pathology, Klinikum rechts der Isar, Munich (Germany); Baurecht, Hansjoerg [Technische Universitaet Muenchen, Department of Statistics, Klinikum rechts der Isar, Institute for Medical Statistics and Epidemiology, Munich (Germany); Ludwig, Georg; Rummeny, Ernst J. [Technische Universitaet Muenchen, Department of Radiology, Klinikum rechts der Isar, Munich (Germany); Piontek, Guido [Technische Universitaet Muenchen, Department of Neuropathology, Munich (Germany); Beer, Ambros J. [Technische Universitaet Muenchen, Department of Radiology, Klinikum rechts der Isar, Munich (Germany); Technische Universitaet Muenchen, Department of Nuclear Medicine, Munich (Germany)

    2010-09-15

    To assess migration of CD34{sup +} human stem cells to the bone marrow of athymic mice by using magnetic resonance (MR) imaging and Resovist, a contrast agent containing superparamagnetic iron oxide (SPIO) particles. All animal and human procedures were approved by our institution's ethics committee, and women had given consent to donate umbilical cord blood (UCB). Balb/c-AnN Foxn1{sup nu}/Crl mice received intravenous injection of 1 x 10{sup 6} (n = 3), 5 x 10{sup 6} (n = 3) or 1 x 10{sup 7} (n = 3) human Resovist-labelled CD34{sup +} cells; control mice received Resovist (n = 3). MR imaging was performed before, 2 and 24 h after transplantation. Signal intensities of liver, muscle and bone marrow were measured and analysed by ANOVA and post hoc Student's t tests. MR imaging data were verified by histological and immunological detection of both human cell surface markers and carboxydextran-coating of the contrast agent. CD34{sup +} cells were efficiently labelled by Resovist without impairment of functionality. Twenty-four hours after administration of labelled cells, MR imaging revealed a significant signal decline in the bone marrow, and histological and immunological analyses confirmed the presence of transplanted human CD34{sup +} cells. Intravenously administered Resovist-labelled CD34{sup +} cells home to bone marrow of mice. Homing can be tracked in vivo by using clinical 1.5-T MR imaging technology. (orig.)

  16. Regenerative feedback resonant circuit

    Science.gov (United States)

    Jones, A. Mark; Kelly, James F.; McCloy, John S.; McMakin, Douglas L.

    2014-09-02

    A regenerative feedback resonant circuit for measuring a transient response in a loop is disclosed. The circuit includes an amplifier for generating a signal in the loop. The circuit further includes a resonator having a resonant cavity and a material located within the cavity. The signal sent into the resonator produces a resonant frequency. A variation of the resonant frequency due to perturbations in electromagnetic properties of the material is measured.

  17. Methodology for nuclear magnetic resonance and ion cyclotron resonance mass spectrometry

    International Nuclear Information System (INIS)

    Sehgal, Akansha

    2014-01-01

    This thesis encompasses methodological developments in both nuclear magnetic resonance and Fourier transform ion cyclotron resonance mass spectrometry. The NMR section explores the effects of scalar relaxation on a coupled nucleus to measure fast exchange rates. In order to quantify these rates accurately, a precise knowledge of the chemical shifts of the labile protons and of the scalar couplings is normally required. We applied the method to histidine where no such information was available a priori, neither about the proton chemical shifts nor about the one-bond scalar coupling constants J( 1 H 15 N), since the protons were invisible due to fast exchange. We have measured the exchange rates of the protons of the imidazole ring and of amino protons in histidine by indirect detection via 15 N. Not only the exchange rate constants, but also the elusive chemical shifts of the protons and the coupling constants could be determined. For the mass spectrometry section, the ion isolation project was initiated to study the effect of phase change of radiofrequency pulses. Excitation of ions in the ICR cell is a linear process, so that the pulse voltage required for ejecting ions must be inversely proportional to the pulse duration. A continuous sweep pulse propels the ion to a higher radius, whereas a phase reversal causes the ion to come to the centre. This represents the principle of 'notch ejection', wherein the ion for which the phase is reversed is retained in the ICR cell, while the remaining ions are ejected. The manuscript also contains a theoretical chapter, wherein the ion trajectories are plotted by solving the Lorentzian equation for the three-pulse scheme used for two-dimensional ICR. Through our simulations we mapped the ion trajectories for different pulse durations and for different phase relations. (author)

  18. Theta-frequency resonance at the cerebellum input stage improves spike-timing on the millisecond time-scale

    Directory of Open Access Journals (Sweden)

    Daniela eGandolfi

    2013-04-01

    Full Text Available The neuronal circuits of the brain are thought to use resonance and oscillations to improve communication over specific frequency bands (Llinas, 1988; Buzsaki, 2006. However, the properties and mechanism of these phenomena in brain circuits remain largely unknown. Here we show that, at the cerebellum input stage, the granular layer generates its maximum response at 5-7 Hz both in vivo following tactile sensory stimulation of the whisker pad and in acute slices following mossy fiber-bundle stimulation. The spatial analysis of granular layer activity performed using voltage-sensitive dye (VSD imaging revealed 5-7 Hz resonance covering large granular layer areas. In single granule cells, resonance appeared as a reorganization of output spike bursts on the millisecond time-scale, such that the first spike occurred earlier and with higher temporal precision and the probability of spike generation increased. Resonance was independent from circuit inhibition, as it persisted with little variation in the presence of the GABAA receptor blocker, gabazine. However, circuit inhibition reduced the resonance area more markedly at 7 Hz. Simulations with detailed computational models suggested that resonance depended on intrinsic granule cells ionic mechanisms: specifically, Kslow (M-like and KA currents acted as resonators and the persistent Na current and NMDA current acted as amplifiers. This form of resonance may play an important role for enhancing coherent spike emission from the granular layer when theta-frequency bursts are transmitted by the cerebral cortex and peripheral sensory structures during sensory-motor processing, cognition and learning.

  19. Sample-size resonance, ferromagnetic resonance and magneto-permittivity resonance in multiferroic nano-BiFeO{sub 3}/paraffin composites at room temperature

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Lei; Li, Zhenyu; Jiang, Jia; An, Taiyu; Qin, Hongwei; Hu, Jifan, E-mail: hujf@sdu.edu.cn

    2017-01-01

    In the present work, we demonstrate that ferromagnetic resonance and magneto-permittivity resonance can be observed in appropriate microwave frequencies at room temperature for multiferroic nano-BiFeO{sub 3}/paraffin composite sample with an appropriate sample-thickness (such as 2 mm). Ferromagnetic resonance originates from the room-temperature weak ferromagnetism of nano-BiFeO{sub 3}. The observed magneto-permittivity resonance in multiferroic nano-BiFeO{sub 3} is connected with the dynamic magnetoelectric coupling through Dzyaloshinskii–Moriya (DM) magnetoelectric interaction or the combination of magnetostriction and piezoelectric effects. In addition, we experimentally observed the resonance of negative imaginary permeability for nano BiFeO{sub 3}/paraffin toroidal samples with longer sample thicknesses D=3.7 and 4.9 mm. Such resonance of negative imaginary permeability belongs to sample-size resonance. - Highlights: • Nano-BiFeO{sub 3}/paraffin composite shows a ferromagnetic resonance. • Nano-BiFeO{sub 3}/paraffin composite shows a magneto-permittivity resonance. • Resonance of negative imaginary permeability in BiFeO{sub 3} is a sample-size resonance. • Nano-BiFeO{sub 3}/paraffin composite with large thickness shows a sample-size resonance.

  20. Depolarization due to the resonance tail during a fast resonance jump

    International Nuclear Information System (INIS)

    Ruth, R.D.

    1980-01-01

    The mechanism of depolarization due to a fast resonance jump is studied. The dominant effect for cases of interest is not dependent on the rate of passage through resonance, but rather on the size of the resonance jump as compared to the width, epsilon, of the resonance. The results are applied to a calculation of depolarization in the AGS at Brookhaven National Laboratory

  1. Neutronic calculation of reactor cells

    International Nuclear Information System (INIS)

    Jaliff, J.O.

    1981-01-01

    Multigroup calculations of cylindrical pin cells were programmed, in Fortran IV, upon the basis of collision probabilities in each energy group. A rational approximation to the fuel-to-fuel collision probability in resonance groups was used. Together with the intermediate resonance theory, cross sections corrected for heterogeneity and absorber interactions were found. For the optimization of the program, the cell of a BWR reactor was taken as reference. Data for such a cell and the reactor's operating conditions are presented. PINCEL is a fast and flexible program, with checked results, around a 69-group library. (M.E.L.) [es

  2. On coupled development of MHD instabilities of Rayleigh-Taylor and Kelvin-Helmholtz types in nonuniform gas-plasmas flows

    International Nuclear Information System (INIS)

    Likhachev, A P; Medin, S A

    2010-01-01

    The simultaneous development of the MHD instabilities of Raylegh-Taylor and Kelvin-Helmholtz types at the interface between high-conducting plasmoid and surrounding non- or low-conducting gas is considered. The linear stage of the RTI development is studied analytically for incompressible and compressible fluids. The nonlinear stage of the individual development of the RTI and the coupled development of both instabilities has been investigated numerically. The time-dependent two-dimensional numerical model based on the solution of the Euler gasdynamic equations with body momentum and energy sources of MHD origin has been developed and used in calculations. A disturbance introducing in the background flow has been periodic with varied assignment type and wave length. Fundamental difference between the results of linear and nonlinear analysis has been revealed. In particular, the increment of the RTI development at nonlinear stage is one-two order of magnitude less than that predicted by linear theory and rather weakly depends on initial disturbance mode. In linear analysis the coupled development of the RTI and the KHI is determined by simple summing of the two effects in the expression of wave increment, whereas in nonlinear case the mutual influence of the instabilities leads to essential alterations in their development, main of which is the intensive 'layer-by-layer' destruction of the plasmoid surface.

  3. Nanoscale imaging of photocurrent enhancement by resonator array photovoltaic coatings

    Science.gov (United States)

    Ha, Dongheon; Yoon, Yohan; Zhitenev, Nikolai B.

    2018-04-01

    Nanoscale surface patterning commonly used to increase absorption of solar cells can adversely impact the open-circuit voltage due to increased surface area and recombination. Here, we demonstrate absorptivity and photocurrent enhancement using silicon dioxide (SiO2) nanosphere arrays on a gallium arsenide (GaAs) solar cell that do not require direct surface patterning. Due to the combined effects of thin-film interference and whispering gallery-like resonances within nanosphere arrays, there is more than 20% enhancement in both absorptivity and photocurrent. To determine the effect of the resonance coupling between nanospheres, we perform a scanning photocurrent microscopy based on a near-field scanning optical microscopy measurement and find a substantial local photocurrent enhancement. The nanosphere-based antireflection coating (ARC), made by the Meyer rod rolling technique, is a scalable and a room-temperature process; and, can replace the conventional thin-film-based ARCs requiring expensive high-temperature vacuum deposition.

  4. New resonance cross section calculational algorithms

    International Nuclear Information System (INIS)

    Mathews, D.R.

    1978-01-01

    Improved resonance cross section calculational algorithms were developed and tested for inclusion in a fast reactor version of the MICROX code. The resonance energy portion of the MICROX code solves the neutron slowing-down equations for a two-region lattice cell on a very detailed energy grid (about 14,500 energies). In the MICROX algorithms, the exact P 0 elastic scattering kernels are replaced by synthetic (approximate) elastic scattering kernels which permit the use of an efficient and numerically stable recursion relation solution of the slowing-down equation. In the work described here, the MICROX algorithms were modified as follows: an additional delta function term was included in the P 0 synthetic scattering kernel. The additional delta function term allows one more moments of the exact elastic scattering kernel to be preserved without much extra computational effort. With the improved synthetic scattering kernel, the flux returns more closely to the exact flux below a resonance than with the original MICROX kernel. The slowing-down calculation was extended to a true B 1 hyperfine energy grid calculatn in each region by using P 1 synthetic scattering kernels and tranport-corrected P 0 collision probabilities to couple the two regions. 1 figure, 6 tables

  5. Acoustic Metacages for Omnidirectional Sound Shielding

    OpenAIRE

    Shen, Chen; Xie, Yangbo; Li, Junfei; Cummer, Steven A.; Jing, Yun

    2017-01-01

    Conventional sound shielding structures typically prevent fluid transport between the exterior and interior. A design of a two-dimensional acoustic metacage with subwavelength thickness which can shield acoustic waves from all directions while allowing steady fluid flow is presented in this paper. The structure is designed based on acoustic gradient-index metasurfaces composed of open channels and shunted Helmholtz resonators. The strong parallel momentum on the metacage surface rejects in-pl...

  6. Narrow dibaryon resonances

    International Nuclear Information System (INIS)

    Kajdalov, A.B.

    1986-01-01

    Experimental data on np interactions indicating to existence of narrow resonances in pp-system are discussed. Possible theoretical interpretations of these resonances are given. Experimental characteristics of the dibaryon resonances with isospin I=2 are considered

  7. Using 3 Tesla magnetic resonance imaging in the pre-operative evaluation of tongue carcinoma.

    Science.gov (United States)

    Moreno, K F; Cornelius, R S; Lucas, F V; Meinzen-Derr, J; Patil, Y J

    2017-09-01

    This study aimed to evaluate the role of 3 Tesla magnetic resonance imaging in predicting tongue tumour thickness via direct and reconstructed measures, and their correlations with corresponding histological measures, nodal metastasis and extracapsular spread. A prospective study was conducted of 25 patients with histologically proven squamous cell carcinoma of the tongue and pre-operative 3 Tesla magnetic resonance imaging from 2009 to 2012. Correlations between 3 Tesla magnetic resonance imaging and histological measures of tongue tumour thickness were assessed using the Pearson correlation coefficient: r values were 0.84 (p Tesla magnetic resonance imaging had 83 per cent sensitivity, 82 per cent specificity, 82 per cent accuracy and a 90 per cent negative predictive value for detecting cervical lymph node metastasis. In this cohort, 3 Tesla magnetic resonance imaging measures of tumour thickness correlated highly with the corresponding histological measures. Further, 3 Tesla magnetic resonance imaging was an effective method of detecting malignant adenopathy with extracapsular spread.

  8. Magnetic Resonance Imaging Characteristics of Ovarian Clear Cell Carcinoma.

    Directory of Open Access Journals (Sweden)

    Wei Wang

    Full Text Available To probe the magnetic resonance imaging (MRI features of ovarian clear cell carcinoma (OCCC.This study retrospectively collected MRI data for 21 pathology-confirmed OCCCs from 19 female patients. The MRI findings were analyzed to determine the tumor size, shape/edge, shape and number of protrusions within the cyst, cystic or necrotic components, signal intensity (SI and enhancement features.The age of the 19 patients ranged from 28 to 63 years (mean age: 53 years. Unilateral tumors were found in 17 patients (17/19, 89%; the average size of all tumors was 10.8 cm. The tumors on MRI were classified into two categories: (a "cystic adnexal mass with solid protrusions" in 12 (57% and (b "solid adnexal mass with cystic areas or necrosis" in 9 (43%. For group a, high to very high SI was observed for most tumors (10/12, 83% on T1-weighted images (T1WIs, and very high SI was observed on T2-weighted images (T2WIs for all 12 tumors. Most solid protrusions were irregular and few in number and exhibited heterogeneous intermediate SI on T1WIs and T2WIs and prolonged enhanced SI in the contrast study. All 9 OCCCs in group b were predominantly solid masses with unequally sized necrotic or cystic areas in which some cysts were located at the periphery of the tumor (4/9, 44%. The solid components in all 9 tumors showed iso- or slightly high SI on T1WIs, heterogeneous iso-high SI on T2WIs and heterogeneous prolonged enhancement. According to FIGO classification, 14 tumors (14/19, 74% were stages I-II, and 5 (5/19, 26% were stages III-IV.On MRI, OCCCs present as large unilateral multilocular or unilocular cystic masses with irregular intermediate SI solid protrusions or predominantly solid masses with cysts or necrosis at an early FIGO stage.

  9. Hollow Microtube Resonators via Silicon Self-Assembly toward Subattogram Mass Sensing Applications.

    Science.gov (United States)

    Kim, Joohyun; Song, Jungki; Kim, Kwangseok; Kim, Seokbeom; Song, Jihwan; Kim, Namsu; Khan, M Faheem; Zhang, Linan; Sader, John E; Park, Keunhan; Kim, Dongchoul; Thundat, Thomas; Lee, Jungchul

    2016-03-09

    Fluidic resonators with integrated microchannels (hollow resonators) are attractive for mass, density, and volume measurements of single micro/nanoparticles and cells, yet their widespread use is limited by the complexity of their fabrication. Here we report a simple and cost-effective approach for fabricating hollow microtube resonators. A prestructured silicon wafer is annealed at high temperature under a controlled atmosphere to form self-assembled buried cavities. The interiors of these cavities are oxidized to produce thin oxide tubes, following which the surrounding silicon material is selectively etched away to suspend the oxide tubes. This simple three-step process easily produces hollow microtube resonators. We report another innovation in the capping glass wafer where we integrate fluidic access channels and getter materials along with residual gas suction channels. Combined together, only five photolithographic steps and one bonding step are required to fabricate vacuum-packaged hollow microtube resonators that exhibit quality factors as high as ∼ 13,000. We take one step further to explore additionally attractive features including the ability to tune the device responsivity, changing the resonator material, and scaling down the resonator size. The resonator wall thickness of ∼ 120 nm and the channel hydraulic diameter of ∼ 60 nm are demonstrated solely by conventional microfabrication approaches. The unique characteristics of this new fabrication process facilitate the widespread use of hollow microtube resonators, their translation between diverse research fields, and the production of commercially viable devices.

  10. Use of chemical fractionation and proton nuclear magnetic resonance to probe the physical structure of the primary plant cell wall

    International Nuclear Information System (INIS)

    Taylor, I.E.P.; Wallace, J.C.; MacKay, A.L.; Volke, F.

    1990-01-01

    Proton magnetic resonance has been used to monitor the microscopic physical properties of etiolated hypocotyl cell walls from Phaseolus vulgaris L. at all stages in a series of chemical fractionations with ammonium oxalate and potassium hydroxide. Solid echo measurements indicate that 75% of the polymers in the intact cell wall, including the cellulose and most of the hemicelluloses, are arranged such that there is almost complete restraint of molecular motion. The chemical fractionations generally altered the physical structures of the remaining cell wall components. Digestion with 0.25% ammonium oxalate/oxalic acid solubilized the pectin and increased the mobility of the hemicellulose I component. Extraction with 4% potassium hydroxide removed the hemicellulose I component and loosened the hemicellulose II. Further extraction with 24% potassium hydroxide removed the hemicellulose II and loosened some of the cellulose. The cellulose crystallinity, as monitored by Jeener echo measurements decreased from 83% to 63% during these fractionations. We conclude that, while hemicellulose I is firmly attached to hemicellulose II, it is not in a closely packed structure. Hemicellulose II is strongly bound to cellulose and has a much more closely packed structure

  11. Dependence of excitation frequency of resonant circuit on RF irradiation position of MRI equipment

    International Nuclear Information System (INIS)

    Shimizu, Masato; Yamada, Tsutomu; Takemura, Yasushi; Niwa, Touru; Inoue, Tomio

    2010-01-01

    Hyperthermia using implants is a cancer treatment in which cancer tissue is heated to over 42.5 deg C to selectively kill the cancer cells. In this study, a resonant circuit was used as an implant, and a weak magnetic field of radiofrequency (RF) pulses from a magnetic resonance imaging (MRI) device was used as an excitation source. We report here how the temperature of the resonant circuit was controlled by changing the excitation frequency of the MRI. As a result, the temperature rise of the resonant circuit was successfully found to depend on its position in the MRI device. This significant result indicates that the temperature of the resonant circuit can be controlled only by adjusting the excitation position. Accurate temperature control is therefore expected to be possible by combining this control technique with the temperature measurement function of MRI equipment. (author)

  12. Magnetic resonance imaging for Human T-cell lymphotropic virus type 1 (HTLV1- associated myelopathy/tropical spastic paraparesis patients: a systematic review

    Directory of Open Access Journals (Sweden)

    Fariba Zemorshidi

    2015-06-01

    Full Text Available Introduction: Human T-cell lymphotropic virus type 1 (HTLV-1 associated myelopathy/tropical spastic paraparesis is a chronic progressive neurologic disease which might be associated by brain and spinal cord atrophy and lesions. Here we systematically reviewed the brain and spinal cord abnormalities reported by using magnetic resonance imaging modality on HTLV-1 associated myelopathy/tropical spastic paraparesis patients. Methods: PubMed was searched for all the relevant articles which used magnetic resonance imaging for patients with human HTLV-1 associated myelopathy/tropical spastic paraparesis disease. Included criteria were all the cohort and case series on with at least 10 patients. We had no time limitation for searched articles, but only English language articles were included in our systematic review. Exclusion criteria were none-English articles, case reports, articles with less than 10 patients, spastic paraparesis patients with unknown etiology, and patients with HTLVII. Results: Total of 14 relevant articles were extracted after studying title, abstracts, and full text of the irrelevant articles. Only 2/14 articles, reported brain atrophy incidence. 5/14 articles studied the brain lesions prevalence. Spinal cord atrophy and lesions, each were studied in 6/14 articles.Discussion: According to the extracted data, brain atrophy does not seem to happen frequently in patients with HTLV-1 associated myelopathy/tropical spastic paraparesis. None-specific brain lesions identified in articles are indicative of low specificity of magnetic resonance imaging technique despite its high sensitivity. Conclusion: Prevalence of spinal cord lesions and atrophy in these patients might be due to the degenerative processes associated with aging phenomenon. Further larger studies in endemic areas can more accurately reveal the specificity of magnetic resonance imaging for these patients.

  13. A surface plasmon resonance biosensor for direct detection of the rabies virus

    Directory of Open Access Journals (Sweden)

    Jing Xu

    2012-01-01

    Full Text Available A surface plasmon resonance biosensor chip was constructed for detection of rabies virus. For the construction of the biosensor chip, N protein specific antibody and N protein specific antibody combined with G protein specific antibody of rabies virus were linked on two different flow cells on one CM5 chip, respectively. The chip was tested for the detection of rabies virus antigens using the crude extract of rabies virus from infected BHK cell strain culture. Tenfold serial dilutions of SRV9 strain virus-infected cell cultures were tested by the biosensor chip to establish the detection limit. The limit detection was approximately 70 pg/ml of nucleoprotein and glycoprotein. The biosensor chip developed in this study was employed for the detection of rabies virus in five suspect infectious specimens of brain tissue from guinea pigs; the results were compared by fluorescent antibody test. Surface plasmon resonance biosensor chip could be a useful automatic tool for prompt detection of rabies virus infection.

  14. Applied neutron resonance theory

    International Nuclear Information System (INIS)

    Froehner, F.H.

    1980-01-01

    Utilisation of resonance theory in basic and applications-oriented neutron cross section work is reviewed. The technically important resonance formalisms, principal concepts and methods as well as representative computer programs for resonance parameter extraction from measured data, evaluation of resonance data, calculation of Doppler-broadened cross sections and estimation of level-statistical quantities from resonance parameters are described. (author)

  15. Ex vivo hyperpolarized MR spectroscopy on isolated renal tubular cells: A novel technique for cell energy phenotyping.

    Science.gov (United States)

    Juul, Troels; Palm, Fredrik; Nielsen, Per Mose; Bertelsen, Lotte Bonde; Laustsen, Christoffer

    2017-08-01

    It has been demonstrated that hyperpolarized 13 C MR is a useful tool to study cultured cells. However, cells in culture can alter phenotype, which raises concerns regarding the in vivo significance of such findings. Here we investigate if metabolic phenotyping using hyperpolarized 13 C MR is suitable for cells isolated from kidney tissue, without prior cell culture. Isolation of tubular cells from freshly excised kidney tissue and treatment with either ouabain or antimycin A was investigated with hyperpolarized MR spectroscopy on a 9.4 Tesla preclinical imaging system. Isolation of tubular cells from less than 2 g of kidney tissue generally resulted in more than 10 million live tubular cells. This amount of cells was enough to yield robust signals from the conversion of 13 C-pyruvate to lactate, bicarbonate and alanine, demonstrating that metabolic flux by means of both anaerobic and aerobic pathways can be quantified using this technique. Ex vivo metabolic phenotyping using hyperpolarized 13 C MR in a preclinical system is a useful technique to study energy metabolism in freshly isolated renal tubular cells. This technique has the potential to advance our understanding of both normal cell physiology as well as pathological processes contributing to kidney disease. Magn Reson Med 78:457-461, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

  16. Paramagnetic particles carried by cell-penetrating peptide tracking of bone marrow mesenchymal stem cells, a research in vitro

    International Nuclear Information System (INIS)

    Liu Min; Guo Youmin; Wu Qifei; Yang Junle; Wang Peng; Wang Sicen; Guo Xiaojuan; Qiang Yongqian; Duan Xiaoyi

    2006-01-01

    The ability to track the distribution and differentiation of stem cells by high-resolution imaging techniques would have significant clinical and research implications. In this study, a model cell-penetrating peptide was used to carry gadolinium particles for magnetic resonance imaging of the mesenchymal stem cells. The mesenchymal stem cells were isolated from rat bone marrow by Percoll and identified by osteogenic differentiation in vitro. The cell-penetrating peptides labeled with fluorescein-5-isothiocyanate and gadolinium were synthesized by a solid-phase peptide synthesis method and the relaxivity of cell-penetrating peptide-gadolinium paramagnetic conjugate on 400 MHz nuclear magnetic resonance was 5.7311 ± 0.0122 mmol -1 s -1 , higher than that of diethylenetriamine pentaacetic acid gadolinium (p < 0.05). Fluorescein imaging confirmed that this new peptide could internalize into the cytoplasm and nucleus. Gadolinium was efficiently internalized into mesenchymal stem cells by the peptide in a time- or concentration-dependent fashion, resulting in intercellular T1 relaxation enhancement, which was obviously detected by 1.5 T magnetic resonance imaging. Cytotoxicity assay and flow cytometric analysis showed the intercellular contrast medium incorporation did not affect cell viability and membrane potential gradient. The research in vitro suggests that the newly constructed peptides could be a vector for tracking mesenchymal stem cells

  17. Photonic metasurface made of array of lens-like SiGe Mie resonators formed on (100) Si substrate via dewetting

    Science.gov (United States)

    Poborchii, Vladimir; Shklyaev, Alexander; Bolotov, Leonid; Uchida, Noriyuki; Tada, Tetsuya; Utegulov, Zhandos N.

    2017-12-01

    Metasurfaces consisting of arrays of high-index Mie resonators concentrating/redirecting light are important for integrated optics, photodetectors, and solar cells. Herein, we report the optical properties of low-Ge-content SiGe lens-like Mie resonator island arrays fabricated via dewetting during Ge deposition on a Si(100) surface at approximately 900 °C. We observe enhancement of the Si interaction with light owing to the efficient island-induced light concentration in the submicron-depth Si layer, which is mediated by both near-field Mie resonance leaking into the substrate and far-field light focusing. Such metasurfaces can improve the Si photodetector and solar-cell performance.

  18. A 1H nuclear magnetic resonance study of structural and organisational changes in the cell

    International Nuclear Information System (INIS)

    Tunnah, Susan K.

    2000-01-01

    Increasing importance is being placed on understanding the role of membrane lipids in many different areas of biochemistry. It is of interest to determine what interactions may occur between membrane lipids and drug species. Furthermore, an increasing body of evidence suggests that membrane lipids are involved in the pathology of numerous diseases such as rheumatoid arthritis, cancer and HIV. Clearly, the more information available on the mechanisms involved in diseases, the greater the potential for identifying a cure or even a prevention. 1 H nuclear magnetic resonance (NMR) spectroscopy was used to study the alterations in membrane lipid organisation and structure in intact, viable cultured cells. Changes in the 1 H NMR spectra and the spin-lattice relaxation measurements of the human K562 and the rat FRTL-5 cell lines were observed on the addition of the fatty acid species: triolein, evening primrose oil, arachidonic acid and ITF 1779. Results indicate that the membrane lipids are reorganised to accommodate the interpolation of these molecules. The spatial arrangement adopted by each of these species appeared to dictate its effect on the lipids. Doxorubicin and menadione, both known to cause oxidative stress, were added to K562 cells. Although both agents are known to act by different mechanisms, the NMR data and scanning electron microscopy suggested that both caused similar alterations in the membrane organisation and lipid fluidity. Protrusions were formed indicating areas of weakness in the membrane. Spin-echo NMR was employed to investigate the action of the thiol-containing compounds, penicillamine, captopril and N-acetylcysteine in erythrocytes under conditions of oxidative stress. Results indicate that while captopril acts as a free radical scavenger, penicillamine may act as either oxidant or reductant. N-acetylcysteine was observed to act as a reducing agent. (author)

  19. Applied neutron resonance theory

    International Nuclear Information System (INIS)

    Froehner, F.H.

    1978-07-01

    Utilisation of resonance theory in basic and applications-oriented neutron cross section work is reviewed. The technically important resonance formalisms, principal concepts and methods as well as representative computer programs for resonance parameter extraction from measured data, evaluation of resonance data, calculation of Doppler-broadened cross sections and estimation of level-statistical quantities from resonance parameters are described. (orig.) [de

  20. Use of three-dimensional time-resolved phase-contrast magnetic resonance imaging with vastly undersampled isotropic projection reconstruction to assess renal blood flow in a renal cell carcinoma patient treated with sunitinib: a case report.

    Science.gov (United States)

    Takayama, Tatsuya; Takehara, Yasuo; Sugiyama, Masataka; Sugiyama, Takayuki; Ishii, Yasuo; Johnson, Kevin E; Wieben, Oliver; Wakayama, Tetsuya; Sakahara, Harumi; Ozono, Seiichiro

    2014-08-14

    New imaging modalities to assess the efficacy of drugs that have molecular targets remain under development. Here, we describe for the first time the use of time-resolved three-dimensional phase-contrast magnetic resonance imaging to monitor changes in blood supply to a tumor during sunitinib treatment in a patient with localized renal cell carcinoma. A 43-year-old Japanese woman with a tumor-bearing but functional single kidney presented at our hospital in July 2012. Computed tomography and magnetic resonance imaging revealed a cT1aN0M0 renal cell carcinoma embedded in the upper central region of the left kidney. She was prescribed sunitinib as neoadjuvant therapy for 8 months, and then underwent partial nephrectomy. Tumor monitoring during this time was done using time-resolved three-dimensional phase-contrast magnetic resonance imaging, a recent technique which specifically measures blood flow in the various vessels of the kidney. This imaging allowed visualization of the redistribution of renal blood flow during treatment, and showed that flow to the tumor was decreased and flows to other areas increased. Of note, this change occurred in the absence of any change in tumor size. The ability of time-resolved three-dimensional phase-contrast magnetic resonance imaging to provide quantitative information on blood supply to tumors may be useful in monitoring the efficacy of sunitinib treatment.