Teatrinukkude muuseum = Museum of Puppet Arts / Liis Lindvere, Raili Paling ; intervjueerinud Margit Mutso

Index Scriptorium Estoniae

Lindvere, Liis

2011-01-01

Tallinnas Lai 1/Nunne 8 asuva muuseumi sisekujundusest. Sisearhitektid: Margit Argus, Raili Paling, Liis Lindvere (KOKO Arhitektid). Ekspositsiooni autor Kalju Kivi. Siltide ja viitade kujunduse autor Andrus Kõresaar

Sõmeru keskushoone = Sõmeru centre building / Ralf Lõoke ; intervjueerinud Margit Mutso

Index Scriptorium Estoniae

Lõoke, Ralf, 1978-

2011-01-01

Sõmeru keskushoone (Kooli 2, Sõmeru alevik) arhitektuursest lahendusest. Arhitektid Maarja Kask, Karli Luik ja Ralf Lõoke pälvisid Eesti Kultuurkapitali aastapreemia (2010) kõrgetasemelise panuse eest Eesti maa-arhitektuuri: Sõmeru keskushoone (kaasautorid Kristiina Arusoo ja Margit Argus) ja Eesti Maanteemuuseumi välialad (kaasautor Pelle-Sten Viiburg)

Tilda Swintoni uskumatu elu / Tilda Swinton ; intervjueerinud Peter Cowie, refereerinud Margit Tõnson

Index Scriptorium Estoniae

Swinton, Tilda, 1960-

2009-01-01

Berliini 59. rahvusvahelise filmifestivali poolt ellu kutsutud ja noortele talentidele mõeldud "Berlinale Talent Campus" vestluste sari nimega "Rambivalgus". Vestlust Berlinale võistlusprogrammi žürii esinaise Tilda Swintoniga modereeris filmiajaloolane Peter Cowie, vahendas Margit Tõnson

Uus õpik julgustab maailma parandama / Triin Vihalemm, Margit Keller, Maie Kiisel ; intervjueerinud Annela Laaneots

Index Scriptorium Estoniae

Vihalemm, Triin, 1968-

2013-01-01

Intervjuu Tartu Ülikooli ajakirjanduse ja kommunikatsiooni instituudi õppejõudude Triin Vihalemma, Margit Kelleri ja Maie Kiiseliga nende e-õpikust "Kuidas parandada maailma? Kommunikatsioon sotsiaalsete muutuste kujundamisel"

Why do dismissed employees need art? / Margit Säde

Index Scriptorium Estoniae

Säde, Margit, 1984-

2009-01-01

"Koondatute kunsti keskus" Tallinna Postimajas 23.-30. aprillini 2009. Eesti Kunstiakadeemia üliõpilaste sotsiaalse kunstiprojekti eesmärgist, sellest osavõtust, dokumentaalfilmi õpikojast, mida viisid läbi Anna Škodenko, Anne-Liis Kogan ja Margit Säde. Valminud tööd ja projekti dokumentatsioon olid väljas detsembris 2009 avatud Anders Härmi kureeritud näitusel "Blue-Collar Blues" Tallinna Kunstihoones

Süütust näpates

Index Scriptorium Estoniae

2007-01-01

Tanel Veenre fotoseeria teatrikostüümidest Draamateatri laval. Stilist: Hanna Tiidus. Naine: Merle Palmiste. Poiss: Joonas (MJ-Models). Jumestus: Margit Soosaar. Juuksed: Jelena Radtsenkova. Kostüümid etendustest "Rohuvoodi" (Aime Unt), "Rehepapp", "Tõeline inspektor koer" (Ene-Liis Semper), "Liilia" (Lilja Blumenfeld), "Mort" (Kersti Varrak), "Potilaadale" (Reet Aus), "Amadeus" (Krista Tool)

5 küsimust Ene Läkile / Ene Läkk ; interv. Ell-Maaja Randküla

Index Scriptorium Estoniae

Läkk, Ene, 1957-

2006-01-01

Ene Läkist, kes on alates 2005. aastast interjööri-, disaini- ja arhitektuuriajakirja "Ruum" peatoimetaja. Ene Läkk, Eesti Sisearhitektide Liidu 2005. a. aastapreemia nominent ajakirjandusliku tegevuse eest, ajakirjast "Ruum". Ill.: 6 värv. vaadet, foto ajakirjanikust

Kunstnike moraalsed valikud kultuurikonfliktides = The moral choices of artists in cultural conflicts

Index Scriptorium Estoniae

2006-01-01

Kaasaegse Kunsti Eesti Keskuse 4. ettekannete päev "Kunstnike moraalsed valikud kultuurikonfliktides" sarjast "Lisandusi eesti kunstiloole" Tallinna Kunstihoones 27.04.2006. Kava, esinevad Margit Sutrop, Johannes Saar, Andres Tali, Marek Järvik, Ene-Liis Semper ja Eero Epner, Marco Laimre. Soome filmirežissööri Pirjo Honkasalo dokumentaalfilmi "Melanhoolia kolm tuba" presentatsioon

Rakvere uus bussijaam = New Bus Terminal in Rakvere / Margit Mutso, Madis Eek

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2000-01-01

Ühekorruseline bussijaamahoone, ooteruum paikneb klaasmahus. Projekteerija, istemööbli disain: Arhitektuuribüroo Eek & Mutso. Arhitektid Margit Mutso, Madis Eek, kaasa töötas Reio Avaste. Konstruktiivne osa, eriosad: Projektbüroo Talone. Projekt 1999, ehitus 1999-2000. 12 ill. Asendiplaan, I korruse plaan, lõiked, välis- ja sisevaated

Hydroxylative activity of Aspergillus niger towards androst-4-ene and androst-5-ene steroids.

Science.gov (United States)

Świzdor, Alina; Panek, Anna; Milecka-Tronina, Natalia

2017-10-01

Aspergillus niger, one of fungal species most frequently used for experimental and industrial-scale biotransformations of various organic compounds, is generally known to transform steroids at 16β position. In this work, application of the strain A. niger KCH910 to bioconversion of dehydroepiandrosterone (DHEA), androstenediol and testosterone is described, with emphasis on the metabolic steps leading to the products. Evidence from this study indicated that incubated 5-ene steroids underwent bioconversion within two metabolic pathways: oxidation by the action of 3β-HSD (3β-hydroxysteroid dehydrogenase) to 4-ene steroids, and minor allylic hydroxylation to epimeric 7-alcohols. Further transformation of the 3-oxo-4-ene metabolites resulted in non-selective 16-hydroxylation. It is the first report on an A. niger strain able to introduce not only 16β- but also 16α-hydroxyl function into steroids. Copyright © 2017. Published by Elsevier Inc.

Mõeldes arhitektuuri välkloengutele = Considering flash lectures on architecture / Margit Mutso

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2010-01-01

7. veebruaril 2008 Von Krahli Teatris alanud arhitektuuri välkloengutest, mille eesmärk oli haarata avalikkust kaasa mõtlema, rääkima meid ümbritsevast keskkonnast ning viia ühiskonda arusaamist, et arhitektuur on meie kõigi asi. Arhitektuurist kutsuti rääkima tuntud äri- ja kultuuriinimesi. Välkloenguid modereerisid Ülar Mark, Margit Mutso ja Mattias Agabus

Hybrid Organic/Inorganic Thiol-ene-Based Photopolymerized Networks

OpenAIRE

Schreck, Kathleen M.; Leung, Diana; Bowman, Christopher N.

2011-01-01

The thiol-ene reaction serves as a more oxygen tolerant alternative to traditional (meth)acrylate chemistry for forming photopolymerized networks with numerous desirable attributes including energy absorption, optical clarity, and reduced shrinkage stress. However, when utilizing commercially available monomers, many thiol-ene networks also exhibit decreases in properties such as glass transition temperature (Tg) and crosslink density. In this study, hybrid organic/inorganic thiol-ene resins ...

Ene Sepp esitles esikteost "Medaljon" / Heli Talinurm

Index Scriptorium Estoniae

Talinurm, Heli

2009-01-01

Ene Sepp esitles 19. veebruaril Rapla Keskraamatukogus oma raamatut, mis pälvis kolmanda koha Eesti Lastekirjanduse Teabekeskuse ja kirjastuse Tänapäev 2008. aasta noorsooromaani võistlusel. Ly Ehini mõtteid, mida Ene Sepa raamat temas tekitas

Vaesusriski muutused Eestis / Ene-Margit Tiit

Index Scriptorium Estoniae

Tiit, Ene-Margit, 1934-

2006-01-01

Seoses Eesti majanduse kiire arenguga tellis sotsiaalministeerium 2005. aastal uue tarbimiskaalude hinnangu, mille aluseks olid leibkonna eelarvehinnangu andmed aastaist 2000-2004 ning hinnati erineva struktuuriga leibkondade tarbimiskulutusi. Diagrammid. Graafikud

Eesti Ajaloomuuseumi Suurgildi hoone. Püsinäitus "Visa hing. 11 000 aastat Eesti ajalugu" = Restoration of the Estonian History Museum Great Guild Hall building, permanent exhibition "Spirit of survival. 11,000 years of Estonian history" / Margit A

Index Scriptorium Estoniae

Argus, Margit, 1981-

2012-01-01

Suurgildi hoone renoveerimisest, sisekujundusest, ekspositsioonist. Sisearhitektid Margit Aule, Liis Lindvere, Margit Argus (Koko Arhitektid). Restaureerimisarhitekt: Mart Keskküla (Restor). Graafilise disaini autorid Jan Tomson, Indrek Sirkel, Mikk Heinsoo, Kaarel Nõmmik, Andrus Kõresaar (Produktsioonigrupp). Ekspositsiooni multimeedia ja interaktsioon: Produktsioonigrupp

Hybrid Organic/Inorganic Thiol-ene-Based Photopolymerized Networks.

Science.gov (United States)

Schreck, Kathleen M; Leung, Diana; Bowman, Christopher N

2011-09-15

The thiol-ene reaction serves as a more oxygen tolerant alternative to traditional (meth)acrylate chemistry for forming photopolymerized networks with numerous desirable attributes including energy absorption, optical clarity, and reduced shrinkage stress. However, when utilizing commercially available monomers, many thiol-ene networks also exhibit decreases in properties such as glass transition temperature (T(g)) and crosslink density. In this study, hybrid organic/inorganic thiol-ene resins incorporating silsesquioxane (SSQ) species into the photopolymerized networks were investigated as a route to improve these properties. Thiol- and ene-functionalized SSQs (SH-SSQ and allyl-SSQ, respectively) were synthesized via alkoxysilane hydrolysis/condensation chemistry, using a photopolymerizable monomer [either pentaerythriol tetrakis(3-mercaptopropionate) (PETMP) or 1,3,5-triallyl-1,3,5-triazine-2,4,6(1H,3H,5H)-trione (TATATO)] as the reaction solvent. The resulting SSQ-containing solutions (SSQ-PETMP and SSQ-TATATO) were characterized, and their incorporation into photopolymerized networks was evaluated.

Synthesis of some 16,17-secoandrost-5-ene derivatives

Directory of Open Access Journals (Sweden)

Gaković Andrea R.

2010-01-01

Full Text Available Starting from 3β-acetoxy-17-oxo-16,17-secoandrost-5-ene-16-nitrile (1, 3β-acetoxy-16,17-secoandrost-5-ene-16-nitrile (4 was synthesized by a three-stage procedure. First, the formyl group of compound 1 was reduced, to yield the alcohol 2. Compound 2 was further transformed to the mesyloxy derivative 3, whose reduction with NaBH3CN gave compound 4. Apart from compound 4 as the main reaction product, two additional products were obtained, for which the GC/MS analysis suggested that they are 8(14 and 14 derivatives of compound 4. Compound 4 was transformed into 3β-hydroxy-16,17-sesoandrost-5-ene-16-nitrile (7, the Oppenauer oxidation of which afforded 3-oxo-16,17-secoandrost-4-ene-16-nitrile (8.

Ene Käpp ali optimizem

Directory of Open Access Journals (Sweden)

Dušana Findeisen

1998-12-01

Full Text Available Na »Konferenci o vlogi in organizaciji izobraževanja odraslih v času prehoda«, ki je bila novembra lani v Tallinnu, glavnem mestu Estonije, smo srečevali nekaj razsvetljenih obrazov organizatorjev. Med njimi je bila Ene Kapp, kratko pristriženih las, živahnega videza in prodornega glasu. Ene Kapp je neprestano bedela nad nami. Tisti, ki so povezani z estonskim izobraževanjem odraslih, jo poznajo že dolgo. Srečujejo se z njo na ANDRAS-u, estonskem združenju za izobraževanje odraslih.

Thiol-ene/methacrylate systems for mechanical damping

Science.gov (United States)

McNair, Olivia; Senyurt, Askim; Wei, Huanyu; Gould, Trent; Piland, Scott; Hoyle, Charles; Savin, Daniel

2010-03-01

Ternary thiol-ene-methacrylate (TEMA) networks as materials for mechanical energy damping are unique to the sports world. Using a photoinitiation process, TEMA systems are formed via an initial thiol-ene step-growth mechanism along with traditional radical polymerization of acrylate and ene monomers. Final networks have two-part morphologies: acrylate homopolymer sectors imbedded in a multi-component mesh. Several (TEMA) systems have been synthesized and analyzed via thermal and mechanical probing. Initial studies on these ternary systems have shown excellent properties compared to traditional ethylene vinyl alcohol (EVA) copolymers. For example, PEMA networks exhibit glass transition temperatures 33 K higher than EVA, resulting in improved damping at room temperature. This research will help develop relationships between tan delta, glass transition and their effects on mechanical energy damping for ternary (TEMA) systems.

5-Ene-4-thiazolidinones - An efficient tool in medicinal chemistry.

Science.gov (United States)

Kaminskyy, Danylo; Kryshchyshyn, Anna; Lesyk, Roman

2017-11-10

The presented review is an attempt to summarize a huge volume of data on 5-ene-4-thiazolidinones being a widely studied class of small molecules used in modern organic and medicinal chemistry. The manuscript covers approaches to the synthesis of 5-ene-4-thiazolidinone derivatives: modification of the C5 position of the basic core; synthesis of the target compounds in the one-pot or multistage reactions or transformation of other related heterocycles. The most prominent pharmacological profiles of 5-ene derivatives of different 4-thiazolidinone subtypes belonging to hit-, lead-compounds, drug-candidates and drugs as well as the most studied targets have been discussed. Currently target compounds (especially 5-en-rhodanines) are assigned as frequent hitters or pan-assay interference compounds (PAINS) within high-throughput screening campaigns. Nevertheless, the crucial impact of the presence/nature of C5 substituent (namely 5-ene) on the pharmacological effects of 5-ene-4-thiazolidinones was confirmed by the numerous listed findings from the original articles. The main directions for active 5-ene-4-thiazolidinones optimization have been shown: i) complication of the fragment in the C5 position; ii) introduction of the substituents in the N3 position (especially fragments with carboxylic group or its derivatives); iii) annealing in complex heterocyclic systems; iv) combination with other pharmacologically attractive fragments within hybrid pharmacophore approach. Moreover, the utilization of 5-ene-4-thiazolidinones in the synthesis of complex compounds with potent pharmacological application is described. The chemical transformations cover mainly the reactions which involve the exocyclic double bond in C5 position of the main core and correspond to the abovementioned direction of the 5-ene-4-thiazolidinone modification. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Miks, kuidas ja kellele? / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2009-01-01

Tiit Ojasoo ja Ene-Liis Semperi "Kuidas seletada pilte surnud jänesele" teatris NO99, Priit Võigemasti "Hecuba pärast" Tallinna Linnateatris ja koreograaf-esitaja Mart Kangro "Can't Get No Satisfaction" Kanuti Gildi saalis

IS-ENES project management - lessons learnt

Science.gov (United States)

Parinet, Marie; Guglielmo, Francesca; Joussaume, Sylvie

2017-04-01

IS-ENES is the distributed e-infrastructure of models, model data and metadata of the European Network for Earth System Modelling (ENES). It has benefitted from two EC FP7 grants and aims towards further European and national funding to achieve sustainability. We highlight here several challenges related to project management that have risen in the course of these two project-phases spanning 8 years. Some challenges are related to the heterogeneity of the activities within IS-ENES, with different groups working on very diverse activities, not necessarily strictly interdependent. An immediate consequence is the need of implementing and setting up in early phases of the project efficient collection and circulation of information to preserve and reinforce the systemic view of the infrastructure as a whole and the pursuit of common goals, including coordinated provision of services. Toward and beyond such common goals, managing IS-ENES, covering both scientific and more strictly management-related aspects, implies a double-paced approach: besides setting up efficient project workflow, there is the need of setting up longer term objectives. This implies, within the project lifetime, to elaborate and implement a coherent organizational (consistent with scientific goals, funding schemes, research and technology landscape) strategy to pursue these goals beyond the project itself. Furthermore, a series of more generic project management challenges will also be listed and can be gathered around 3 main objectives: ease the internal processes in order to optimize the work, anticipate delays and budget issues, and motivate the project teams by ensuring an efficient internal and external communication.

Multi-chamber and multi-layer thiol-ene microchip for cell culture

DEFF Research Database (Denmark)

Tan, H. Y.; Hemmingsen, Mette; Lafleur, Josiane P.

2014-01-01

We present a multi-layer and multi-chamber microfluidic chip fabricated using two different thiol-ene mixtures. Sandwiched between the thiol-ene chip layers is a commercially available membrane whose morphology has been altered with coatings of thiol-ene mixtures. Experiments have been conducted ...... with the microchip and shown that the fabricated microchip is suitable for long term cell culture....

Lapse ülalpidamise hind / Ene-Margit Tiit

Index Scriptorium Estoniae

Tiit, Ene-Margit, 1934-

2005-01-01

Tutvustav artikkel sotsiaalministeeriumi tellimusel läbiviidud uuringust, mille eesmärgiks oli välja töötada lapse kõikidest vajadustest lähtuv ühtne metoodika lapse ülalpidamiskulude arvutamiseks ühes kuus. Tabelid. Diagrammid. Vt. ka lk. 15-16: Kaplan, Signe. Metoodika kasutamisvõimalusi

Vaata inimest. Näe elu / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2011-01-01

Teater NO99 lavastusest "The Rise and Fall of Estonia" Nokia Kontserdimajas. Idee, kontseptsioon ja lavastus Tiit Ojasoo ja Ene-Liis Semper. Viktor Pelevini "Kollane nool" Ugala teatris, lavastaja Mart Koldits

Preparation and Preliminary Dielectric Characterization of Structured C60-Thiol-Ene Polymer Nanocomposites Assembled Using the Thiol-Ene Click Reaction

Directory of Open Access Journals (Sweden)

Hanaa M. Ahmed

2015-11-01

Full Text Available Fullerene-containing materials have the ability to store and release electrical energy. Therefore, fullerenes may ultimately find use in high-voltage equipment devices or as super capacitors for high electric energy storage due to this ease of manipulating their excellent dielectric properties and their high volume resistivity. A series of structured fullerene (C60 polymer nanocomposites were assembled using the thiol-ene click reaction, between alkyl thiols and allyl functionalized C60 derivatives. The resulting high-density C60-urethane-thiol-ene (C60-Thiol-Ene networks possessed excellent mechanical properties. These novel networks were characterized using standard techniques, including infrared spectroscopy (FTIR, differential scanning calorimetry (DSC, dynamic mechanical analysis (DMA, and thermal gravimetric analysis (TGA. The dielectric spectra for the prepared samples were determined over a broad frequency range at room temperature using a broadband dielectric spectrometer and a semiconductor characterization system. The changes in thermo-mechanical and electrical properties of these novel fullerene-thiol-ene composite films were measured as a function of the C60 content, and samples characterized by high dielectric permittivity and low dielectric loss were produced. In this process, variations in chemical composition of the networks were correlated to performance characteristics.

Highly tailorable thiol-ene based emulsion-templated monoliths

DEFF Research Database (Denmark)

Lafleur, J. P.; Kutter, J. P.

2014-01-01

The attractive surface properties of thiol-ene polymers combined with their ease of processing make them ideal substrates in many bioanalytical applications. We report the synthesis of highly tailorable emulsion-templated porous polymers and beads in microfluidic devices based on off-stoichiometr......The attractive surface properties of thiol-ene polymers combined with their ease of processing make them ideal substrates in many bioanalytical applications. We report the synthesis of highly tailorable emulsion-templated porous polymers and beads in microfluidic devices based on off......-stoichiometry thiolene chemistry. The method allows monolith synthesis and anchoring inside thiol-ene microchannels in a single step. Variations in the monomer stoichiometric ratios and/or amount of porogen used allow for the creation of extremely varied polymer morphologies, from foam-like materials to dense networks...

Surface functionalized thiol-ene waveguides for fluorescence biosensing in microfluidic devices

DEFF Research Database (Denmark)

Feidenhans'l, Nikolaj Agentoft; Lafleur, Josiane P.; Jensen, Thomas Glasdam

2013-01-01

-ene waveguides were fabricated from 40% excess thiol thiol-ene to ensure the presence of thiol functional groups at the surface of the waveguide. Biotin alkyne was photografted at specific locations using a photomask, directly at the interface between the microfluidic channel and the thiol-ene waveguide prior...

Fabrication and bonding of thiol-ene-based microfluidic devices

DEFF Research Database (Denmark)

Sikanen, Tiina M; Lafleur, Josiane P.; Moilanen, Maria-Elisa

2013-01-01

In this work, the bonding strength of microchips fabricated by thiol-ene free-radical polymerization was characterized in detail by varying the monomeric thiol/allyl composition from the stoichiometric ratio (1:1) up to 100% excess of thiol (2:1) or allyl (1:2) functional groups. Four different...... properties for each application. Here, a capillary electrophoresis separation is performed to demonstrate the attractive properties of stoichiometric thiol-ene microchips....

Evaluation and Control of Thiol-ene/Thiol-epoxy Hybrid Networks.

Science.gov (United States)

Carioscia, Jacquelyn A; Stansbury, Jeffrey W; Bowman, Christopher N

2007-03-08

The development of thiol-ene/thiol-epoxy hybrid networks offers the advantage of tailorable polymerization kinetics while producing a highly crosslinked, high T(g) polymer that has significantly reduced shrinkage stress. Stoichiometric mixtures of pentaerythritol tetra(3-mercaptopropionate) (PETMP)/triallyl-1,3,5-triazine-2,4,6-trione (TATATO) (thiol-ene, mixture 1) and PETMP/bisphenol a diglycidyl ether (BADGE) (thiol-epoxy, mixture 2) were prepared and hybrid mixtures of 75/25, 50/50, 25/75, and 10/90 w/w of mixtures 1 and 2 were polymerized using a combination of both radical and anionic initiation. The light exposure timing and the relative initiation conditions of the two types were used to control the order and relative rates of the radical and anionic polymerizations. The 50/50 w/w thiol-ene/thiol-epoxy hybrid material exhibited a final stress of only 0.2 MPa, which is 90 % lower than the stress developed in a control dimethacrylate resin. Kinetic analysis indicates composition affects network development in thiol-ene/thiol-epoxy hybrid networks and produces materials with robust mechanical properties.

Rahvusvaheliselt pärjatud õpivara eesti keeles ja kirjanduses / Helin Puksand, Reet Bobõlski, Margit Ross ; intervjueeris Krista Kerge

Index Scriptorium Estoniae

Puksand, Helin, 1970-

2015-01-01

Eesti õpivarale antud rahvusvahelised auhinnad: Best European Learning Material Silver Award 2014 Helin Puksandi, Reet Bobõlski ja Margit Rossi eesti keele õpikule "Punkt" (2013) ja Best European Schoolbook Silver Award 2012 samade autorite eesti keele õpikule "Peegel 3" (2011). Best European Schoolbook Bronze Award 2006 Jaanus Vaiksoo, Sirje Toomla ja Kadri Liivese aabitsale "Ilus emakeel" (2005).

Fabrication and bonding of thiol-ene-based microfluidic devices

International Nuclear Information System (INIS)

Sikanen, Tiina M; Moilanen, Maria-Elisa; Lafleur, Josiane P; Zhuang, Guisheng; Jensen, Thomas G; Kutter, Jörg P

2013-01-01

In this work, the bonding strength of microchips fabricated by thiol-ene free-radical polymerization was characterized in detail by varying the monomeric thiol/allyl composition from the stoichiometric ratio (1:1) up to 100% excess of thiol (2:1) or allyl (1:2) functional groups. Four different thiol-ene to thiol-ene bonding combinations were tested by bonding: (i) two stoichiometric layers, (ii) two layers bearing complementary excess of thiols and allyls, (iii) two layers both bearing excess of thiols, or (iv) two layers both bearing excess of allyls. The results showed that the stiffness of the cross-linked polymer plays the most crucial role regarding the bonding strength. The most rigid polymer layers were obtained by using the stoichiometric composition or an excess of allyls, and thus, the bonding combinations (i) and (iv) withstood the highest pressures (up to the cut-off value of 6 bar). On the other hand, excess of thiol monomers yielded more elastic polymer layers and thus decreased the pressure tolerance for bonding combinations (ii) and (iii). By using monomers with more thiol groups (e.g. tetrathiol versus trithiol), a higher cross-linking ratio, and thus, greater stiffness was obtained. Surface characterization by infrared spectroscopy confirmed that the changes in the monomeric thiol/allyl composition were also reflected in the surface chemistry. The flexibility of being able to bond different types of thiol-enes together allows for tuning of the surface chemistry to yield the desired properties for each application. Here, a capillary electrophoresis separation is performed to demonstrate the attractive properties of stoichiometric thiol-ene microchips. (technical note)

Investigations of thiol-modified phenol derivatives for the use in thiol-ene photopolymerizations.

Science.gov (United States)

Reinelt, Sebastian; Tabatabai, Monir; Fischer, Urs Karl; Moszner, Norbert; Utterodt, Andreas; Ritter, Helmut

2014-01-01

Thiol-ene photopolymerizations gain a growing interest in academic research. Coatings and dental restoratives are interesting applications for thiol-ene photopolymerizations due to their unique features. In most studies the relative flexible and hydrophilic ester derivative, namely pentaerythritoltetra(3-mercaptopropionate) (PETMP), is investigated as the thiol component. Thus, in the present study we are encouraged to investigate the performance of more hydrophobic ester-free thiol-modified bis- and trisphenol derivatives in thiol-ene photopolymerizations. For this, six different thiol-modified bis- and trisphenol derivatives exhibiting four to six thiol groups are synthesized via the radical addition of thioacetic acid to suitable allyl-modified precursors and subsequent hydrolysis. Compared to PETMP better flexural strength and modulus of elasticity are achievable in thiol-ene photopolymerizations employing 1,3,5-triallyl-1,3,5-triazine-2,4,6-trione (TATATO) as the ene derivative. Especially, after storage in water, the flexural strength and modulus of elasticity is twice as high compared to the PETMP reference system.

Investigations of thiol-modified phenol derivatives for the use in thiol–ene photopolymerizations

Science.gov (United States)

Reinelt, Sebastian; Tabatabai, Monir; Fischer, Urs Karl; Moszner, Norbert; Utterodt, Andreas

2014-01-01

Summary Thiol–ene photopolymerizations gain a growing interest in academic research. Coatings and dental restoratives are interesting applications for thiol–ene photopolymerizations due to their unique features. In most studies the relative flexible and hydrophilic ester derivative, namely pentaerythritoltetra(3-mercaptopropionate) (PETMP), is investigated as the thiol component. Thus, in the present study we are encouraged to investigate the performance of more hydrophobic ester-free thiol-modified bis- and trisphenol derivatives in thiol–ene photopolymerizations. For this, six different thiol-modified bis- and trisphenol derivatives exhibiting four to six thiol groups are synthesized via the radical addition of thioacetic acid to suitable allyl-modified precursors and subsequent hydrolysis. Compared to PETMP better flexural strength and modulus of elasticity are achievable in thiol–ene photopolymerizations employing 1,3,5-triallyl-1,3,5-triazine-2,4,6-trione (TATATO) as the ene derivative. Especially, after storage in water, the flexural strength and modulus of elasticity is twice as high compared to the PETMP reference system. PMID:25161731

Investigations of thiol-modified phenol derivatives for the use in thiol–ene photopolymerizations

Directory of Open Access Journals (Sweden)

Sebastian Reinelt

2014-07-01

Full Text Available Thiol–ene photopolymerizations gain a growing interest in academic research. Coatings and dental restoratives are interesting applications for thiol–ene photopolymerizations due to their unique features. In most studies the relative flexible and hydrophilic ester derivative, namely pentaerythritoltetra(3-mercaptopropionate (PETMP, is investigated as the thiol component. Thus, in the present study we are encouraged to investigate the performance of more hydrophobic ester-free thiol-modified bis- and trisphenol derivatives in thiol–ene photopolymerizations. For this, six different thiol-modified bis- and trisphenol derivatives exhibiting four to six thiol groups are synthesized via the radical addition of thioacetic acid to suitable allyl-modified precursors and subsequent hydrolysis. Compared to PETMP better flexural strength and modulus of elasticity are achievable in thiol–ene photopolymerizations employing 1,3,5-triallyl-1,3,5-triazine-2,4,6-trione (TATATO as the ene derivative. Especially, after storage in water, the flexural strength and modulus of elasticity is twice as high compared to the PETMP reference system.

Vägivald ja propaganda

Index Scriptorium Estoniae

2006-01-01

8. IV-28. V Tallinna Kunstihoones Elin Kardi, Marco Laimre, Marko Mäetamme ja Andres Tali näitus "Vägivald ja propaganda". 26. IV-7. V näituse raames emergency biennale, rahvusvaheline rändnäitus Tšetšeenia toetuseks. 27. IV Kaasaegse Kunsti Eesti Keskuse IV ettekannete päev "Kunstniku moraalsed valikud liberaalse demokraatia ja islami kokkupõrgetes". Esinevad Margit Sutrop, Johannes Saar, Marek Järvik, Ene-Liis Semper & Eero Epner ning näitusel "Vägivald ja propaganda" osalevad kunstnikud

Eesti Maanteemuuseumi välialad = Estonian Road Museum, outdoor areas / Ralf Lõoke, Karli Luik, Maarja Kask ; intervjueerinud Margit Mutso

Index Scriptorium Estoniae

Lõoke, Ralf, 1978-

2011-01-01

Arhitektid: Maarja Kask, Karli Luik, Ralf Lõoke, Pelle-Sten Viiburg (Salto AB). Näituse kujundajad: Malle Jürgenson, Tea Tammelaan, Krista Lepland (Laika, Belka & Strelka). Maarja Kask, Karli Luik ja Ralf Lõoke pälvisid Eesti Kultuurkapitali aastapreemia (2010) kõrgetasemelise panuse eest Eesti maa-arhitektuuri: Eesti Maanteemuuseumi välialad (kaasautor Pelle-Sten Viiburg), Sõmeru keskushoone (kaasautorid Kristiina Arusoo ja Margit Argus)

Evaluation and Control of Thiol-ene/Thiol-epoxy Hybrid Networks

OpenAIRE

Carioscia, Jacquelyn A.; Stansbury, Jeffrey W.; Bowman, Christopher N.

2007-01-01

The development of thiol-ene/thiol-epoxy hybrid networks offers the advantage of tailorable polymerization kinetics while producing a highly crosslinked, high Tg polymer that has significantly reduced shrinkage stress. Stoichiometric mixtures of pentaerythritol tetra(3-mercaptopropionate) (PETMP)/triallyl-1,3,5-triazine-2,4,6-trione (TATATO) (thiol-ene, mixture 1) and PETMP/bisphenol a diglycidyl ether (BADGE) (thiol-epoxy, mixture 2) were prepared and hybrid mixtures of 75/25, 50/50, 25/75, ...

Rapid and simple preparation of thiol-ene emulsion-templated monoliths and their application as enzymatic microreactors

DEFF Research Database (Denmark)

Lafleur, Josiane P; Senkbeil, Silja; Novotny, Jakub

2015-01-01

A novel, rapid and simple method for the preparation of emulsion-templated monoliths in microfluidic channels based on thiol-ene chemistry is presented. The method allows monolith synthesis and anchoring inside thiol-ene microchannels in a single photoinitiated step. Characterization by scanning...... electron microscopy showed that the methanol-based emulsion templating process resulted in a network of highly interconnected and regular thiol-ene beads anchored solidly inside thiol-ene microchannels. Surface area measurements indicate that the monoliths are macroporous, with no or little micro...

Teoretiska perspektiv på kön, klass och gränsöverskridanden i akademin. Margit Abenius som forskare och litteraturkritiker

Directory of Open Access Journals (Sweden)

Marta Ronne

2006-01-01

Full Text Available THEORETICAL APPROACHES TO GENDER AND IDENTITY IN STUDIES OF THE INTELLECTUAL.MARGIT ABENIUS AND THE MAKING OF A FEMALE CRITIC. The aim of this article is todiscuss some of the most important feminist approaches to Pierre Bourdieu’ssociology of culture and the way in which they make possible new interpre-tations of gender and identity. Feminist readings of Bourdieu, from Toril Moi1991 to very recent contributions, have developed a new concept of gender asa part of the general social field and of a ”gender habitus”. These theoretical,non-essentialist standpoints can be combined both with intersectional analy-sis and with quite recent feminist concepts of ”women” as ”social class”(Lovell and ”women” as ”seriality” (Young. Here I use my own study ofthe Swedish literary critic Margit Abenius (1899–1970 to exemplify howthese different theoretical approaches can be brought together. A possibilityof combining feminist readings of Bourdieu with Zygmunt Bauman’s theoryof identity is also discussed in relation to contemporary debate on the con-cepts of subjectivity and identity.

Ene-Liis Semper : hindan päeva, kui teen ühte asja / Ene-Liis Semper ; interv. Jaanus Kulli

Index Scriptorium Estoniae

Semper, Ene-Liis, 1969-

2008-01-01

Teatri- ja videokunstnik Ene-Liis Semper oma elust ja tööst. Lisaks repliik "Parim päev on tööst prii päev" ja peagi Teater NO99s esietenduvast William Shakespeare'i lavastusest "Muinasjutuline "Perikles"

Kulka aastapreemiate žürii hinnang = Comments from the panel of judges / Laila Põdra, Eva Hirvesoo, Tiit Sild, Epp Lankots ; intervjueerinud Margit Mutso

Index Scriptorium Estoniae

2011-01-01

Arhitektuuriaastast 2010. Eesti Kultuurkapitali aastapreemia - Maarja Kask, Karli Luik, Ralf Lõoke, Kristiina Arusoo, Margit Argus, Pelle-Sten Viiburg (Sõmeru keskusehoone, maanteemuuseumi välialad). Arhitektuuri sihtkapitali arhitektuuripreemia - Hannes Koppel (Kuressaare rannahoone), Raul Vaiksoo (eramu), restaureerimispreemia - Jaan Jõgi (Laupa mõis), sisearhitektuuri preemia - Leila Pärtelpoeg (Röa mõis), tegevuspreemia - Karin Hallas-Murula, Eesti Arhitektuurikeskus

On the reaction of the nitroso group with olefins. Mechanisms of ene reactions

International Nuclear Information System (INIS)

Seymour, C.A.; Greene, F.D.

1982-01-01

Intra- and intermolecular isotope effects point to a two-step process for the reaction of pentafluoronitrosobenzene with tetramethylethylene to afford the ene product, rate-determining formation of an intermediate (for which the arizidine N-oxide is suggested) followed by C-H (or C-D) cleavage to the ene product

Antibiofouling hybrid dendritic Boltorn/star PEG thiol-ene cross-linked networks.

Science.gov (United States)

Bartels, Jeremy W; Imbesi, Philip M; Finlay, John A; Fidge, Christopher; Ma, Jun; Seppala, Jonathan E; Nystrom, Andreas M; Mackay, Michael E; Callow, James A; Callow, Maureen E; Wooley, Karen L

2011-06-01

A series of thiol-ene generated amphiphilic cross-linked networks was prepared by reaction of alkene-modified Boltorn polyesters (Boltorn-ene) with varying weight percent of 4-armed poly(ethylene glycol) (PEG) tetrathiol (0-25 wt%) and varying equivalents of pentaerythritol tetrakis(3-mercaptopropionate) (PETMP) (0-64 wt%). These materials were designed to present complex surface topographies and morphologies, with heterogeneity of surface composition and properties and robust mechanical properties, to serve as nontoxic antibiofouling coatings that are amenable to large-scale production for application in the marine environment. Therefore, a two-dimensional matrix of materials compositions was prepared to study the physical and mechanical properties, over which the compositions spanned from 0 to 25 wt% PEG tetrathiol and 0-64 wt% PETMP (the overall thiol/alkene (SH/ene) ratios ranged from 0.00 to 1.00 equiv), with both cross-linker weight percentages calculated with respect to the weight of Boltorn-ene. The Boltorn-ene components were prepared through the esterification of commercially available Boltorn H30 with 3-butenoic acid. The subsequent cross-linking of the Boltorn-PEG-PETMP films was monitored using IR spectroscopy, where it was found that near-complete consumption of both thiol and alkene groups occurred when the stoichiometry was ca. 48 wt% PETMP (0.75 equiv SH/ene, independent of PEG amount). The thermal properties of the films showed an increase in T(g) with an increase in 4-armed PEG-tetrathiol wt%, regardless of the PETMP concentration. Investigation of the bulk mechanical properties in dry and wet states found that the Young's modulus was the greatest at 48 wt% PETMP (0.75 equiv of SH/ene). The ultimate tensile strength increased when PETMP was constant and the PEG concentration was increased. The Young's modulus was slightly lower for wet films at constant PEG or constant PETMP amounts, than for the dry samples. The nanoscopic surface features were

A Study of Functional Polymer Colloids Prepared Using Thiol-Ene/Yne Click Chemistry

Science.gov (United States)

Durham, Olivia Z.

This project demonstrates the first instance of thiol-ene chemistry as the polymerization method for the production of polymer colloids in two-phase heterogeneous suspensions, miniemulsions, and emulsions. This work was also expanded to thiol-yne chemistry for the production of polymer particles containing increased crosslinking density. The utility of thiol-ene and thiol-yne chemistries for polymerization and polymer modification is well established in bulk systems. These reactions are considered 'click' reactions, which can be defined as processes that are both facile and simple, offering high yields with nearly 100% conversion, no side products, easy product separation, compatibility with a diverse variety of commercially available starting materials, and orthogonality with other chemistries. In addition, thiol-ene and thiol-yne chemistry follow a step-growth mechanism for the development of highly uniform polymer networks, where polymer growth is dependent on the coupling of functional groups. These step-growth polymerization systems are in stark contrast to the chain-growth mechanisms of acrylic and styrenic monomers that have dominated the field of conventional heterogeneous polymerizations. Preliminary studies evaluated the mechanism of particle production in suspension and miniemulsion systems. Monomer droplets were compared to the final polymer particles to confirm that particle growth occurred through the polymerization of monomer droplets. Additional parameters examined include homogenization energy (mechanical mixing), diluent species and concentration, and monomer content. These reactions were conducted using photoinitiation to yield particles in a matter of minutes with diameters in the size range of several microns to hundreds of microns in suspensions or submicron particles in miniemulsions. Improved control over the particle size and size distribution was examined through variation of reaction parameters. In addition, a method of seeded suspension

Surface modification of cyclomatrix polyphosphazene microsphere by thiol-ene chemistry and lectin recognition

International Nuclear Information System (INIS)

Chen, Chen; Zhu, Xue-yan; Gao, Qiao-ling; Fang, Fei; Huang, Xiao-jun

2016-01-01

Graphical abstract: A new synthetic route leading to polyphosphazene cyclomatrix microsphere with various functional groups has achieved via thiol-ene click modification. Herein, hexacholorocyclophosphazene (HCCP) crosslinked with bisphenol-S and 4,4′-diallyl bisphenol-S to generate broadly dispersed microspheres. Thiol-ene modification under UV irradiation not only presented high efficiency and flexibility for post-functionalization, but also imposed no harm on global morphology and crosslinked skeleton of such microspheres. - Highlights: • Functional polyphosphazene microspheres with high chemical flexibility were synthesized by thiol-ene modification. • Polyphosphazene microspheres possessed high thermal stability. • Glycosylated polyphosphazene microspheres showed affinity to lectin Con-A, which inferred potential application in biomedicine. - Abstract: A new synthetic route leading to functional polyphosphazene cyclomatrix microsphere has been developed via thiol-ene click modification. Hexacholorocyclophosphazene (HCCP) was crosslinked with both bisphenol-S and 4,4′-diallyl bisphenol-S to obtain vinyl polyphosphazene microspheres (VPZM) in order to ensure high crosslinking degree and introduce vinyl moieties. Compared to the microspheres obtained by HCCP and bisphenol-S, the size of VPZM was broadly dispersed from 400 nm to 1.40 μm. Thiol-ene click reactions were carried out to attach functional groups, such as glucosyl, carboxyl, ester and dodecyl groups onto polyphosphazene microspheres, which demonstrated no change in morphology and size after modification. Solid state NMR (SSNMR) and Fourier transform infrared spectoscopy (FT-IR) results showed that the vinyl moieties were introduced in the period of crosslinking and functionalization was also successful via click reactions. Moreover, the microspheres presented a little difference in thermal properties after modification. Concanavalin A (Con-A) fluorescent adsorption was also observed for

Surface modification of cyclomatrix polyphosphazene microsphere by thiol-ene chemistry and lectin recognition

Energy Technology Data Exchange (ETDEWEB)

Chen, Chen; Zhu, Xue-yan; Gao, Qiao-ling; Fang, Fei; Huang, Xiao-jun, E-mail: hxjzxh@zju.edu.cn

2016-11-30

Graphical abstract: A new synthetic route leading to polyphosphazene cyclomatrix microsphere with various functional groups has achieved via thiol-ene click modification. Herein, hexacholorocyclophosphazene (HCCP) crosslinked with bisphenol-S and 4,4′-diallyl bisphenol-S to generate broadly dispersed microspheres. Thiol-ene modification under UV irradiation not only presented high efficiency and flexibility for post-functionalization, but also imposed no harm on global morphology and crosslinked skeleton of such microspheres. - Highlights: • Functional polyphosphazene microspheres with high chemical flexibility were synthesized by thiol-ene modification. • Polyphosphazene microspheres possessed high thermal stability. • Glycosylated polyphosphazene microspheres showed affinity to lectin Con-A, which inferred potential application in biomedicine. - Abstract: A new synthetic route leading to functional polyphosphazene cyclomatrix microsphere has been developed via thiol-ene click modification. Hexacholorocyclophosphazene (HCCP) was crosslinked with both bisphenol-S and 4,4′-diallyl bisphenol-S to obtain vinyl polyphosphazene microspheres (VPZM) in order to ensure high crosslinking degree and introduce vinyl moieties. Compared to the microspheres obtained by HCCP and bisphenol-S, the size of VPZM was broadly dispersed from 400 nm to 1.40 μm. Thiol-ene click reactions were carried out to attach functional groups, such as glucosyl, carboxyl, ester and dodecyl groups onto polyphosphazene microspheres, which demonstrated no change in morphology and size after modification. Solid state NMR (SSNMR) and Fourier transform infrared spectoscopy (FT-IR) results showed that the vinyl moieties were introduced in the period of crosslinking and functionalization was also successful via click reactions. Moreover, the microspheres presented a little difference in thermal properties after modification. Concanavalin A (Con-A) fluorescent adsorption was also observed for

Episodic nature of the delta 4-ene and delta 5-ene steroidogenic pathways and their relationship to the adreno-gonadal axis in stallions.

Science.gov (United States)

Ganjam, V K

1979-01-01

Changes in the daily secretory patterns of testosterone and other 17 beta-hydroxyandrogen, total oestrogens and total corticoids were investigated in 7 stallions. Pulsatile fluctuations in plasma hormone levels were found in the serial blood samples collected hourly for 24 h in all animals. The plasma profiles indicated that corticoids, oestrogens and androgens were secreted episodically at all times in stallions. A significant correlation was observed between the precursor and products of delta 4-ene and delta 5-ene pathways and in inverse correlation (r = -0.68; P less than 0.01) was observed between total androgens and total corticoids. The significance of these episodic fluctuations of the major steroid hormones are discussed.

Kandidaadid : Ene Ergma versus Toomas Hendrik Ilves

Index Scriptorium Estoniae

2006-01-01

Artiklis vastatakse küsimustele, kes oleksid Kadriorus Ene Ergma ja Toomas Hendrik Ilvese nõunikud, millist sõnumit kannaks nende esimene iseseisvuspäeva kõne, kuidas nad tähistaksid oma võitu presidendivalimistel, kellele nad annaksid Maarjamaa Risti, kuhu nad teeksid oma esimese välisvisiidi

Tandem Wittig-ene reaction approach to kainic acid

Digital Repository Service at National Institute of Oceanography (India)

Majik, M.S.; Parameswaran, P.S.; Tilve, S.G.

The first example of a tandem Wittig-intramolecular ene reaction approach and its application toward the synthesis of kainic acid is reported. The synthetic pathway involves conversion of prenyl bromide into phosphorane 3, followed by one-pot Wittig...

Functionalization of embedded thiol-ene waveguides for evanescent wave induced fluorescence detection in a microfluidic device

DEFF Research Database (Denmark)

Feidenhans'l, Nikolaj Agentoft; Jensen, Thomas Glasdam; Lafleur, Josiane P.

2013-01-01

We demonstrate the use of functional surface groups inherently present on off-stoichiometric thiol−ene polymers, for site-specific immobilization of biomolecules and detection by evanescent wave-induced fluorescence. An optofluidic chip featuring an embedded thiol−ene waveguide was selectively...... functionalized with biotin using photografting. The biotin was used for immobilization of fluorescently labelled streptavidin, and experiments revealed a linear correlation between streptavidin concentration and fluorescent intensity. To further demonstrate the attractiveness of using thiol−ene for optofluidic...

Investigations of thiol-modified phenol derivatives for the use in thiol–ene photopolymerizations

OpenAIRE

Sebastian Reinelt; Monir Tabatabai; Urs Karl Fischer; Norbert Moszner; Andreas Utterodt; Helmut Ritter

2014-01-01

Summary Thiol–ene photopolymerizations gain a growing interest in academic research. Coatings and dental restoratives are interesting applications for thiol–ene photopolymerizations due to their unique features. In most studies the relative flexible and hydrophilic ester derivative, namely pentaerythritoltetra(3-mercaptopropionate) (PETMP), is investigated as the thiol component. Thus, in the present study we are encouraged to investigate the performance of more hydrophobic ester-free thiol-m...

An academic with ambition / Ene Ergma ; interv. Kadri Kukk

Index Scriptorium Estoniae

Ergma, Ene, 1944-

2006-01-01

Intervjuus Riigikogu asespiikriga käsitletakse kõrghariduse korraldust, professorite rohkust kõrgkoolides, võimalikku kandideerimist Tartu ülikooli rektori kohale, omandatud poliitilisi kogemusi ning ajude äravoolu Eestist. Ene Ergma CV

Sa uurisid ekspressionismi 1960ndatel ja 70ndatel... / Ene Lamp

Index Scriptorium Estoniae

Lamp, Ene

2005-01-01

2004. a. ilmunud raamatu "Ekspressionism" eest Eesti Kultuurkapitali suure kunstipreemia (100000 kr.) saanud Ene Lamp ekspressionismi tähenduse muutumiset, ekspressionismi rollist eesti kunstis, oma tulevikuplaanidest

Ene-Liiz Semper. Anton Litvin. Bogdan Mamonov

Index Scriptorium Estoniae

2005-01-01

Veebruaris Madridis toimunud Euroopa kunstilaada ARCO jaoks Vene saatkonna galerii poolt koostatud kunstinäitus TRINITY toimub nüüd Tallinnas Vene saatkonna galeriis. Kuraatorid Masha ja Andrei Melnikovid. Osalevad Ene-Liis Semper videoga ArtVideo, vene kunstnik Bogdan Mamonov maaliseeriaga "Ma kanoniseerisin oma sõpru" ja vene kunstnik Anton Litvin fotoprojektiga "Punktuatsioon". Madridis näitas Semper videot "Nimetu"

Proof of a conjecture of Colliot-Th\\'el\\`ene

OpenAIRE

Denef, Jan

2011-01-01

We prove a conjecture of Colliot-Th\\'el\\`ene that implies the Ax-Kochen Theorem on p-adic forms. We obtain it as an easy consequence of a diophantine excision theorem whose proof forms the body of the present paper.

preparation of bicyclic lactones using lewis acids catalyzed ene

African Journals Online (AJOL)

Administrator

The synthesis of the cis-fused bicyclic lactones relies extensively on the Lewis acid ... having an allylic hydrogen (an"ene") and a compound containing an electron .... observed that the lithium enolate obtained from 3-methyl-2(5H)- furanone ...

Preparation and Characterization of Fluorinated Hydrophobic UV-Crosslinkable Thiol-Ene Polyurethane Coatings

Directory of Open Access Journals (Sweden)

Wenjing Xia

2017-08-01

Full Text Available The polyurethane prepolymer terminated with a double bond was synthesized using isophorone diisocyanate (IPDI, hydroxyl terminated polybutadiene (HTPB, 1,4-butanediol (BDO, and 2-hydroxyethyl acrylate (HEA. Then, a series of innovative UV-curable polyurethane coatings were prepared by blending ene-terminated polyurethane, fluoroacrylate monomer, and multifunctional thiol crosslinker upon UV exposure. The incorporation of fluoroacrylate monomer and multifunctional thiols into polyurethane coatings significantly enhanced the hydrophobic property, mechanical property, pencil hardness, and glossiness of the polyurethane coatings. This method of preparing UV crosslinkable, hydrophobic polyurethane coatings based on thiol-ene chemistry exhibited numerous advantages over other UV photocuring systems.

ENE-Mates - A public information program for women

International Nuclear Information System (INIS)

Nagashima, Kyoko

1995-01-01

Japan depends on import for more than 80 percent of its total energy supply. Nuclear energy is one of the most promising alternatives to oil. It plays a significant role for energy supply in terms of reliability, economic viability and reduction of CO 2 emissions. In order to secure needed capacity, the Government concentrates its efforts on acquiring public acceptance of nuclear power as well as ensuring the safety of plants and improving plant capability and reliability. An opinion poll, done by the Japanese Government in Sep. of 1990, showed that 73.3 percent of man and 57.4 percent of women think that nuclear power is necessary to secure energy supply. Nuclear Power Engineering Corporation (NUPEC) employs various methods for information services arid, in particular, electric power generation including nuclear with an assignment from the Japanese Government. Public information activities by the Nuclear Power Engineering Corporation (NUPEC) are as follows: a) Telephone QA service to respond to public inquiries; b) Publishing the 'Nuclear Newsletter' monthly and various brochures; c) Information service by personal computer network Atomnet concerning energy in general, and operation/trouble informations of nuclear plants; d) Distribution and service of personal computers to local governments offices/museums, etc., for users ranging from children to adults to gather nuclear related information; e) Organization of female monitors 'ENE-MATES' to have lecture meetings and site tours. ENE-MATES - A Public Information Program For Women. As a 1990 opinion poll shows, women's feelings about nuclear energy differ from that of men. Women are more sensitive and anxious than men on nuclear energy issues. To improve this situation several programs for women have been planned and implemented.'ENE-MATES' program is one of these cases. It's purpose is to encourage women, centering around house wives, to have unbiased understanding of energy-related issues

Novel Thiol-Ene Hybrid Coating for Metal Protection

Directory of Open Access Journals (Sweden)

Mona Taghavikish

2016-04-01

Full Text Available A novel hybrid anticorrosion coating with dual network of inorganic (Si–O–Si and organic bonds (C–S–C was prepared on metal through an in situ sol-gel and thiol-ene click reaction. This novel interfacial thin film coating incorporates (3-mercaptopropyl trimethoxysilane (MPTS and 1,4-di(vinylimidazolium butane bisbromide based polymerizable ionic liquid (PIL to form a thiol-ene based photo-polymerized film, which on subsequent sol-gel reaction forms a thin hybrid interfacial layer on metal surface. On top of this PIL hybrid film, a self-assembled nanophase particle (SNAP coating was employed to prepare a multilayer thin film coating for better corrosion protection and barrier performance. The novel PIL hybrid film was characterised for structure and properties using Fourier transform infrared spectroscopy (FTIR, differential scanning calorimetry (DSC, and thermogravimetric analysis (TGA. The corrosion protection performance of the multilayer coating was examined using potentiodynamic polarization and electrochemical impedance spectroscopy (EIS. The results reveal that this novel double layer coating on metal offers excellent protection against corrosion and has remarkably improved the barrier effect of the coating.

DFT Investigation of the Palladium-Catalyzed Ene-Yne Coupling

DEFF Research Database (Denmark)

Henriksen, Signe Teuber; Tanner, David Ackland; Skrydstrup, T.

2010-01-01

). Concerning chemoselectivity, the calculations also clarify why the ene-yne coupling is able to dominate over plausible alternative reaction pathways such as alkene homocoupiing and alkyne polymerization. The role of the phosphine ligand at various stages of the catalytic cycle has also been delineated....

Teoretiska perspektiv på kön, klass och gränsöverskridanden i akademin. Margit Abenius som forskare och litteraturkritiker

OpenAIRE

Marta Ronne

2006-01-01

THEORETICAL APPROACHES TO GENDER AND IDENTITY IN STUDIES OF THE INTELLECTUAL.MARGIT ABENIUS AND THE MAKING OF A FEMALE CRITIC. The aim of this article is todiscuss some of the most important feminist approaches to Pierre Bourdieu’ssociology of culture and the way in which they make possible new interpre-tations of gender and identity. Feminist readings of Bourdieu, from Toril Moi1991 to very recent contributions, have developed a new concept of gender asa part of the general social field and ...

Synthesis and characterization of thiol-ene functionalized siloxanes and evaluation of their polymerization kinetics, network properties, and dental applications

Science.gov (United States)

Cole, Megan A.

We explored formation-structure-property relationships in thiol-ene functionalized oligosiloxanes to create crosslinked networks. Specifically, nine oligomers were synthesized, three with thiol-functional silane repeats and three with allyl-functional silane repeats. Structural variations in each oligomer were systematically induced through the incorporation of non-reactive repeats bearing either diphenyl or di-n-octyl moieties, and the oligomer molecular weight was limited by the presence of monofunctional silane condensation species. The molecular weights and chain compositions of all oligomers were ascertained and subsequently used in the evaluation of network properties formed upon photopolymerization of thiol- and ene-functional reactants. Polymerization kinetics of the thiol-ene functionalized siloxanes were also investigated using photoinitiation owing to the spatial and temporal control afforded by this technique. In particular, the effects of the viscosity of the ene-functionalized oligomer and the degree of thiol functionalization on the observed polymerization rate were determined. Results showed that the speed of polymerization varied with changes to the rate-limiting step, which was heavily influenced by neighboring non-reactive functionalities. Moreover, the thiol-ene reaction was found to exhibity unimolecular termination exclusively in siloxane-based systems. Proposed use of the thiol-ene functionalized siloxane system as a dental impression material necessitated the development of a redox initiation scheme. Evaluation of the benzoylperoxide/dimethyl-p-toluidine redox pair in traditional systems showed bulk thiol-ene polymerizations comparable to photoinitiation with the added advantage of uninhibited depth control, as also demonstrated in small molecule thiol-ene coupling reactions initiated by this same redox system. Application of the redox pair to the siloxane system allowed for the viscoelastic properties as well as the feature replication

Preparation of Biomolecule Microstructures and Microarrays by Thiol–ene Photoimmobilization

NARCIS (Netherlands)

Weinrich, Dirk; Köhn, Maja; Jonkheijm, Pascal; Westerlind, Ulrika; Dehmelt, Leif; Engelkamp, Hans; Christianen, Peter C.M.; Kuhlmann, Jürgen; Maan, Jan C.; Nüsse, Dirk; Schröder, Hendrik; Wacker, Ron; Voges, Edgar; Breinbauer, Rolf; Kunz, Horst; Niemeyer, Christof M.; Waldmann, Herbert

2010-01-01

A mild, fast and flexible method for photoimmobilization of biomolecules based on the light-initiated thiol–ene reaction has been developed. After investigation and optimization of various surface materials, surface chemistries and reaction parameters, microstructures and microarrays of biotin,

Thiol-ene reaction as tool for crosslinking of polynorbornene micelles in the nanoscale

Science.gov (United States)

Rupp, Barbara; Bauer, Thomas; Slugovc, Christian

2009-08-01

The thiol-ene reaction is a established photoreaction of multifunctional thiols and enes. Virtually any type of ene will participate in a free radical polymerisation process with a thiol. An advantage over many other photochemical reactions is that the reaction proceeds almost as rapidly in ambient conditions as in inert atmosphere. In this work we introduce the UV-crosslinking of polynorbornenes made by ring opening metathesis polymerization making use of the residual double bond in the polymer backbone. The crosslinking experiments were done in thin films and were followed by FTIR measurements, to proof the accessibility of double-bonds in the polymers for the addition of the thiols. As a result of these pre-experiments we created flexible and light transmitting films. To further increase the scope of this reaction, amphiphilic block copolymers were prepared and used to form block copolymer micelles in a selective solvent, which were subsequently crosslinked with pentaerythritol tetra(3-mercaptopropionate) (PETMP). FT-IR, DLS and SEM-measurements were used to prove the successful crosslinking and thus nanoparticle formation.

Ene ja Tõnis Kask pole valikuga rahul / Tiit Tuumalu

Index Scriptorium Estoniae

Tuumalu, Tiit, 1971-

2003-01-01

Eesti Filmiajakirjanike Ühing andis auhinna Aasta film 2002 mängufilmile "Agent Sinikael" : režissöör Marko Raat. Viimane sai preemiaks 12 000 krooni. Auhinna rahastajad omanimelise fondi kaudu Eesti Rahvuskultuuri Fondi juures Ene ja Tõnis Kask peavad "Nimed marmortahvlil" väljajätmist isegi nominentide hulgast shokeerivaks

Orented immobilization of farnesylated proteins by the thiol-ene reaction

NARCIS (Netherlands)

Weinrich, Dirk; Lin, Po-Chiao; Jonkheijm, Pascal; Nguyen, Uyen T.T.; Schröder, Hendrik; Niemeyer, Christof M.; Alexandrov, Kirill; Goody, Roger; Waldmann, Herbert

2010-01-01

Anchoring the protein: Proteins were immobilized rapidly under mild conditions by thiol-ene photocoupling between S-farnesyl groups attached to a genetically encodable “CAAX-box” tetrapeptide sequence (A is aliphatic) at the C terminus of the protein and surface-exposed thiols (see scheme). This

Simple preparation of thiol-ene particles in glycerol and surface functionalization by thiol-ene chemistry (TEC) and surface chain transfer free radical polymerization (SCT-FRP)

DEFF Research Database (Denmark)

Hoffmann, Christian; Chiaula, Valeria; Yu, Liyun

2018-01-01

functionalization of excess thiol groups via photochemical thiol-ene chemistry (TEC) resulting in a functional monolayer. In addition, surface chain transfer free radical polymerization (SCT-FRP) was used for the first time to introduce a thicker polymer layer on the particle surface. The application potential...

Spray-deposition and photopolymerization of organic-inorganic thiol-ene resins for fabrication of superamphiphobic surfaces.

Science.gov (United States)

Xiong, Li; Kendrick, Laken L; Heusser, Hannele; Webb, Jamie C; Sparks, Bradley J; Goetz, James T; Guo, Wei; Stafford, Christopher M; Blanton, Michael D; Nazarenko, Sergei; Patton, Derek L

2014-07-09

Superamphiphobic surfaces, exhibiting high contact angles and low contact angle hysteresis to both water and low surface tension liquids, have attracted a great deal attention in recent years because of the potential of these materials in practical applications such as liquid-resistant textiles, self-cleaning surfaces, and antifouling/anticorrosion coatings. In this work, we present a simple strategy for fabricating of superamphiphobic coatings based on photopolymerization of hybrid thiol-ene resins. Spray-deposition and UV photopolymerization of thiol-ene resins containing hydrophobic silica nanoparticles and perfluorinated thiols provide a multiscale topography and low-energy surface that endows the surface with superamphiphobicity. The wettability and chemical composition of the surfaces were characterized by contact-angle goniometry and X-ray photoelectron spectroscopy, respectively. The hierarchical roughness features of the thiol-ene surfaces were investigated with field-emission scanning electron microscopy. Droplet impact and sandpaper abrasion tests indicate the coatings respectively possess a robust antiwetting behavior and good mechanical durability.

Fabrication of Biomolecule Microarrays Using Rapid Photochemical Surface Patterning in Thiol-Ene-Based Microfluidic Devices.

Science.gov (United States)

Jönsson, Alexander; Lafleur, Josiane P

2018-01-01

In many biochip applications, it is advantageous to be able to immobilize biomolecules at specific locations on the surface of solid supports. In this protocol, we describe a photochemical surface patterning procedure based on thiol-ene/yne photochemistry which allows for the simple and rapid selective patterning of biomolecules on thiol-ene solid supports. We describe the preparation of solid supports which are required for the immobilization, including porous monoliths, as well as two different immobilization schemes based on biotin-streptavidin interactions and covalent linkage via free amino groups respectively.

Ene-yne Cross-Metathesis for the Preparation of 2,3-Diaryl-1,3-dienes

Directory of Open Access Journals (Sweden)

Meriem K. Abderrezak

2017-11-01

Full Text Available Ene-yne cross-metathesis from alkynes and ethylene is a useful method to produce substituted conjugated butadiene derivatives. If this method has been used with aliphatic alkynes, it has however never been used starting from diarylacetylenes as internal alkynes. We show that the ene-yne cross-metathesis catalyzed by the second generation Hoveyda ruthenium catalyst provides the 2,3-diarylbuta-1,3-dienes under 3 atm of ethylene at 100 °C. The scope and limitations of the reaction have been evaluated starting from unsymmetrical functionalized diarylacetylene derivatives hence leading to unsymmetrical 2,3-diarylbuta-1,3-dienes in a straightforward and environmentally acceptable manner.

Evaluation of fracture toughness and mechanical properties of ternary thiol-ene-methacrylate systems as resin matrix for dental restorative composites.

Science.gov (United States)

Beigi, Saeed; Yeganeh, Hamid; Atai, Mohammad

2013-07-01

Study and evaluation of fracture toughness, flexural and dynamic mechanical properties, and crosslink density of ternary thiol-ene-methacrylate systems and comparison with corresponding conventional methacrylate system were considered in the present study. Urethane tetra allyl ether monomer (UTAE) was synthesized as ene monomer. Different formulations were prepared based on combination of UTAE, BisGMA/TEGDMA and a tetrathiol monomer (PETMP). The photocuring reaction was conducted under visible light using BD/CQ combination as photoinitiator system. Mechanical properties were evaluated via measuring flexural strength, flexural modulus and fracture toughness. Scanning electron microscopy (SEM) was utilized to study the morphology of the fractured specimen's cross section. Viscoelastic properties of the samples were also determined by dynamic mechanical thermal analysis (DMTA). The same study was performed on a conventional methacrylate system. The data were analyzed and compared by ANOVA and Tukey HSD tests (significance level=0.05). The results showed improvement in fracture toughness of the specimens containing thiol-ene moieties. DMTA revealed a lower glass transition temperature and more homogenous structure for thiol-ene containing specimens in comparison to the system containing merely methacrylate monomer. The flexural modulus and flexural strength of the specimens with higher thiol-ene content were lower than the neat methacrylate system. The SEM micrographs of the fractured surface of specimens with higher methacrylate content were smooth and mirror-like (shiny) which represent brittle fracture. The thiol-ene-methacrylate system can be used as resin matrix of dental composites with enhanced fracture toughness in comparison to the methacrylate analogous. Copyright © 2013 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

Chalcogenidobis(ene-1,2-dithiolate)molybdenum(IV) complexes (chalcogenide E = O, S, Se): probing Mo≡E and ene-1,2-dithiolate substituent effects on geometric and electronic structure.

Science.gov (United States)

Sugimoto, Hideki; Tano, Hiroyuki; Suyama, Koichiro; Kobayashi, Tomoya; Miyake, Hiroyuki; Itoh, Shinobu; Mtei, Regina P; Kirk, Martin L

2011-02-07

New square-pyramidal bis(ene-1,2-dithiolate)MoSe complexes, [Mo(IV)Se(L)(2)](2-), have been synthesised along with their terminal sulfido analogues, [Mo(IV)S(L)(2)](2-), using alkyl (L(C(4)H(8))), phenyl (L(Ph)) and methyl carboxylate (L(COOMe)) substituted dithiolene ligands (L). These complexes now complete three sets of Mo(IV)O, Mo(IV)S and Mo(IV)Se species that are coordinated with identical ene-1,2-dithiolate ligands. The [alkyl substituted Mo(S/Se)(L(C(4)H(8)))(2)](2-) complexes were reported in prior investigations (H. Sugimoto, T. Sakurai, H. Miyake, K. Tanaka and H. Tsukube, Inorg. Chem. 2005, 44, 6927, H. Tano, R. Tajima, H. Miyake, S. Itoh and H. Sugimoto, Inorg. Chem. 2008, 47, 7465). The new series of complexes enable a systematic investigation of terminal chalcogenido and supporting ene-1,2-dithiolate ligand effects on geometric structure, electronic structure, and spectroscopic properties. X-ray crystallographic analysis of these (Et(4)N)(2)[MoEL(2)] (E = terminal chalocogenide) complexes reveals an isostructural Mo centre that adopts a distorted square pyramidal geometry. The M≡E bond distances observed in the crystal structures and the ν(M≡E) vibrational frequencies indicate that these bonds are weakened with an increase in L→Mo electron donation (L(COOMe) < L(Ph) < L(C(4)H(8))), and this order is confirmed by an electrochemical study of the complexes. The (77)Se NMR resonances in MoSeL complexes appear at lower magnetic fields as the selenido ion became less basic from MoSeL(C(4)H(8)), MoSeL(Ph) and MoSeL(COOMe). Electronic absorption and resonance Raman spectroscopies have been used to assign key ligand-field, MLCT, LMCT and intraligand CT bands in complexes that possess the L(COOMe) ligand. The presence of low-energy intraligand CT transition in these MoEL(COOMe) compounds directly probes the electron withdrawing nature of the -COOMe substituents, and this underscores the complex electronic structure of square pyramidal bis(ene-1

NO99 Põhuteater = NO99 Straw Theatre / Ralf Lõoke, Maarja Kask ; intervjueerinud Margit Mutso

Index Scriptorium Estoniae

Lõoke, Ralf, 1978-

2012-01-01

Põhuteatri arhitektid Maarja Kask, Karli Luik, Ralf Lõoke, Pelle-Sten Viiburg (Salto Arhitektid) ja Ene-Liis Semper pälvisid EK arhitektuuri sihtkapitali 2011. a. arhitektuuripreemia vormitähendustes edasi liikunud ning arhitektuurile kui sündmusele ja kohaloomele keskendunud aktsiooni eest. Konstruktor Tõnu Peipmann

Rapid photochemical surface patterning of proteins in thiol-ene based microfluidic devices

DEFF Research Database (Denmark)

Lafleur, Josiane P.; Kwapiszewski, Radoslaw; Jensen, Thomas Glasdam

2013-01-01

! 17 SH nm"2. Biotin alkyne was patterned directly inside thiol–ene microchannels prior to conjugation with fluorescently labelled streptavidin. The surface bound conjugates were detected by evanescent waveinduced fluorescence (EWIF), demonstrating the success of the grafting procedure and its...

Investigations of step-growth thiol-ene polymerizations for novel dental restoratives.

Science.gov (United States)

Lu, Hui; Carioscia, Jacquelyn A; Stansbury, Jeffery W; Bowman, Christopher N

2005-12-01

The goal of this work was to investigate the feasibility of formulating novel dental restorative materials that utilize a step-growth thiol-ene photopolymerization. Particularly, we are aiming to significantly reduce the polymerization shrinkage and shrinkage stress while retaining adequate physical properties as compared to current dimethacrylatre-based systems. The thiol-ene system is composed of a 4:3 molar mixture of triallyl-1,3,5-triazine-2,4,6-trione (TATATO) and pentaerythritol tetramercaptopropionate (PETMP). The simultaneous measurement of shrinkage stress and functional group conversion was performed. Solvent extraction of unreacted monomers and dynamic mechanical analysis on the polymer networks that were formed were also studied. Flexural strength was measured for both filled and unfilled PETMP/TATATO and Bis-GMA/TEGDMA systems. Photopolymerization of PETMP/TATATO occurs at a much higher rate, with the maximum polymerization rate six times faster, than Bis-GMA/TEGDMA cured under the identical conditions. The results from the simultaneous measurement of shrinkage stress and conversion showed that the onset of shrinkage stress coincides with the delayed gel point conversion, which is predicted to be 41% for the 3:4 stoichiometric PETMP/TATATO resin composition. The maximum shrinkage stress developed for PETMP/TATATO was about 0.4 MPa, which was only approximately 14% of the maximum shrinkage stress of the Bis-GMA/TEGDMA system. Adequate flexural strength and flexural modulus values were obtained for both filled and unfilled PETMP/TATATO systems. The dramatically reduced shrinkage stress, increased polymerization rate, significance increased functional group conversion, and decreased leachable species are all benefits for the use-of thiol-ene systems as potential dental restorative materials.

Heat- and light-induced thiol-ene oligomerization of soybean oil-based polymercaptan

Science.gov (United States)

Polymercaptanized soybean oil (PMSO), the product of a thiol-ene reaction between soybean oil and hydrogen sulfide, is a material of interest as a lubricant additive and polymer precursor. We investigated with gel permeation chromatography, nuclear magnetic resonance (one-dimensional and two-dimensi...

Patterned Hydrophilization of Nanoporous 1,2‐PB by Thiol‐ene Photochemistry

DEFF Research Database (Denmark)

Berthold, Anton; Sagar, Kaushal Shashikant; Ndoni, Sokol

2011-01-01

is monitored by FT‐IR, UV–Vis, contact angle, and gravimetry. Overall quantum yields are calculated for the two thiol‐ene “click” reactions in nano‐confinement, neatly revealing their chain‐like nature. Top–down photolithographic patterning is demonstrated, realizing hydrophilic nanoporous “corridors...

Photocured thiol-ene based optical fluorescence sensor for determination of gold(III)

Energy Technology Data Exchange (ETDEWEB)

Çubuk, Soner, E-mail: sonercubuk@marmara.edu.tr; Kahraman, Memet Vezir; Yetimoğlu, Ece Kök; Kenan, Sibel

2014-02-17

Graphical abstract: -- Highlights: •Photopolymerized fluorescence sensor for Au(III) analysis has been developed. •Preparation of polymeric sensor is simple and quick. •Fluorescence sensor used for analysis of Au(III) in real samples. -- Abstract: This study describes the preparation and the characterization of a new thiol-ene based polymeric fluorescence sensor by photo initiated polymerization of trimethylolpropane tris(3-mercaptopropionate), 2-hydroxyethylacrylate, and 2,4,6-triallyloxy-1,3,5-triazine which are used as monomers and also a photo initiator (2,2-dimethoxy-2-phenylacetophenone) for its usage as optical sensor for gold ions. The thiol-ene based polymeric membrane sensor was characterized by using attenuated total reflectance-fourier transform infrared spectroscopy (ATR-FTIR) and scanning electron microscopy (SEM). The response characteristics of the sensors including dynamic range, pH effect, response time, and the effect of foreign ions were investigated. Fluorescence spectra showed that the excitation/emission maxima of the membrane were at 379/425 nm, respectively.

Photocured thiol-ene based optical fluorescence sensor for determination of gold(III)

International Nuclear Information System (INIS)

Çubuk, Soner; Kahraman, Memet Vezir; Yetimoğlu, Ece Kök; Kenan, Sibel

2014-01-01

Graphical abstract: -- Highlights: •Photopolymerized fluorescence sensor for Au(III) analysis has been developed. •Preparation of polymeric sensor is simple and quick. •Fluorescence sensor used for analysis of Au(III) in real samples. -- Abstract: This study describes the preparation and the characterization of a new thiol-ene based polymeric fluorescence sensor by photo initiated polymerization of trimethylolpropane tris(3-mercaptopropionate), 2-hydroxyethylacrylate, and 2,4,6-triallyloxy-1,3,5-triazine which are used as monomers and also a photo initiator (2,2-dimethoxy-2-phenylacetophenone) for its usage as optical sensor for gold ions. The thiol-ene based polymeric membrane sensor was characterized by using attenuated total reflectance-fourier transform infrared spectroscopy (ATR-FTIR) and scanning electron microscopy (SEM). The response characteristics of the sensors including dynamic range, pH effect, response time, and the effect of foreign ions were investigated. Fluorescence spectra showed that the excitation/emission maxima of the membrane were at 379/425 nm, respectively

Rapid photochemical surface patterning of proteins in thiol-ene based microfluidic devices

DEFF Research Database (Denmark)

Lafleur, Josiane P.; Kwapiszewski, Radoslaw; Jensen, Thomas Glasdam

2012-01-01

” and “ene” monomers present in the microfluidic chip bulk material provides a simple and efficient way of tuning the chip’s surface chemistry. Here, thiol-ene chips displaying an excess of functional thiol groups at their surfaces are functionalized with biotin and streptavidin in a controlled fashion using...

Superhydrophobic hybrid inorganic-organic thiol-ene surfaces fabricated via spray-deposition and photopolymerization.

Science.gov (United States)

Sparks, Bradley J; Hoff, Ethan F T; Xiong, Li; Goetz, James T; Patton, Derek L

2013-03-13

We report a simple and versatile method for the fabrication of superhydrophobic inorganic-organic thiol-ene coatings via sequential spray-deposition and photopolymerization under ambient conditions. The coatings are obtained by spray-deposition of UV-curable hybrid inorganic-organic thiol-ene resins consisting of pentaerythritol tetra(3-mercaptopropionate) (PETMP), triallyl isocyanurate (TTT), 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane (TMTVSi), and hydrophobic fumed silica nanoparticles. The spray-deposition process and nanoparticle agglomeration/dispersion provide surfaces with hierarchical morphologies exhibiting both micro- and nanoscale roughness. The wetting behavior, dependent on the concentration of TMTVSi and hydrophobic silica nanoparticles, can be varied over a broad range to ultimately provide coatings with high static water contact angles (>150°), low contact angle hysteresis, and low roll off angles (spray-deposition and UV-cure process on a variety of substrate surfaces including glass, paper, stone, and cotton fabric.

Preliminary Engineering Report contaminated groundwater seeps 317/319/ENE area

International Nuclear Information System (INIS)

1996-01-01

When the Resource Conservation and Recovery Act Facility Investigation (RFI) in the 317/319/ENE Area of Argonne National Laboratory-East (ANL-E) was being completed, groundwater was discovered moving to the surface through a series of seeps. The seeps are located approximately 600 ft south of the ANL fence line in Waterfall Glen Forest Preserve. Samples of this water were collected and analyzed for selected parameters. Two of five seeps sampled were found to contain detectable levels of organic contaminants. Three chemical species were identified: chloroform (14-25 μg/L), carbon tetrachloride (56-340 μg/L), and tetrachloroethylene (3-6 μg/L). The other seeps did not contain detectable levels of volatile organic compounds (VOCs). The water issuing from these two contaminated seeps flows into a narrow ravine, where it is visible as a trickle of water flowing through sand and gravel deposits on the floor of the ravine. Approximately 100-ft downstream of the seep area, the contaminated water is no longer visible, having drained back into the soil in the bed of the ravine. Figure 1 shows the location of the 317/319/ENE Area in relation to the ANL-E site and the Waterfall Glen Forest Preserve

Stereoselectivity in ene reactions with 1O2: matrix effects in polymer supports, photo-oxygenation of organic salts and asymmetric synthesis.

Science.gov (United States)

Griesbeck, Axel G; Bartoschek, Anna; Neudörfl, Jörg; Miara, Claus

2006-01-01

The ene reaction of chiral allylic alcohols is applied as a tool for the investigation of intrapolymer effects by means of the stereoselectivity of the singlet-oxygen addition. The diastereo selectivity strongly depends on the structure of the polymer, the substrate loading degree and also on the degree of conversion demonstrating additional supramolecular effects evolving during the reaction. The efficiency and the stability of polymer-bound sensitizers were evaluated by the ene reaction of singlet oxygen with citronellol. The ene reaction with chiral ammonium salts of tiglic acid was conducted under solution phase conditions or in polystyrene beads under chiral contact ion-pair conditions. The products thus obtained precipitate during the photoreaction as ammonium salts. Moderate asymmetric induction was observed for this procedure for the first time.

Synergistic Diazo-OH Insertion/Conia-Ene Cascade Catalysis for the Stereoselective Synthesis of γ-Butyrolactones and Tetrahydrofurans.

Science.gov (United States)

Hunter, Arianne C; Schlitzer, Steven C; Sharma, Indrajeet

2016-11-02

A novel and highly efficient diazo-OH insertion/Conia-ene cascade reaction of readily available homopropargylic acids and alcohols with diazo carbonyl compounds is described. The cascade reaction involves a synergistic Rh/Ag/Au catalyst cocktail and proceeds instantly with a variety of substituted diazo compounds and acids/alcohols to provide functionalized γ-butyrolactones and tetrahydrofurans with complete regio- and stereoselectivity. The unprecedented rate-enhancement, complete stereoselectivity, and the enabling of new Conia-ene cyclizations suggest a concerted [4+1]-cycloaddition reaction pathway under synergistic (Rh/Ag/Au)-catalysis conditions. © 2016 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

One-step fabrication of PEGylated fluorescent nanodiamonds through the thiol-ene click reaction and their potential for biological imaging

Science.gov (United States)

Huang, Hongye; Liu, Meiying; Tuo, Xun; Chen, Junyu; Mao, Liucheng; Wen, Yuanqing; Tian, Jianwen; Zhou, Naigen; Zhang, Xiaoyong; Wei, Yen

2018-05-01

Over the past years, fluorescent carbon nanoparticles have got growing interest for biological imaging. Fluorescent nanodiamonds (FNDs) are novel fluorescent carbon nanoparticles with multitudinous useful properties, including remarkable fluorescence properties, extremely low toxicity and high refractive index. However, facile preparation of FNDs with designable properties and functions from non-fluorescent detonation nanodiamonds (DNDs) has demonstrated to be challengeable. In this work, we reported for the first time that preparation of Polyethylene glycol (PEG) functionalized FNDs through a one-step thiol-ene click reaction using thiol containing PEG (PEG-SH) as the coating agent. Based on the characterization results, we demonstrated that PEG-SH could be efficiently introduced on DNDs to obtain FNDs through the thiol-ene click chemistry. The resultant FND-PEG composites showed high water dispersibility, strong fluorescence and low cytotoxicity. Moreover, FND-PEG composites could be internalized by cells and displayed good cell dyeing performance. All of these features implied that FND-PEG composites are of great potential for biological imaging. Taken together, a facile one-step strategy based on the one-step thiol-ene click reaction has been developed for efficient preparation of FND-PEG composites from non-fluorescent DNDs. The strategy should be also useful for fabrication of many other functional FNDs via using different thiol containing compounds for the universality of thiol-ene click reaction.

Stavovi medicinskih sestara u Hrvatskoj o primarnom oživljavanju prijevremeno rođene novorođenčadi

OpenAIRE

Bilić, Iva; Prpić, Igor; Radić, Jelena; Vukelić, Petar; Petrović, Ana; Juretić, Emilija; Furlan, Ivanka

2008-01-01

CILJ: Cilj istraživanja bilo je ispitati stavove medicinskih sestara u Hrvatskoj o primarnom oživljavanju prijevremeno rođene djece. METODE: Pisanom anketom ispitivana je dob, roditeljstvo, radno iskustvo i mjesto rada te stavovi medicinskih sestara iz Hrvatske o primarnom oživljavanju prijevremeno rođene djece. Anketirano je 174 medicinskih sestara; 49 zaposlenih u rađaonici ili na mjestima rada sa trudnicama (Rađ/Tr), 79 u pedijatrijskim/ neonatološkim jedinicama intenzivnog liječenja (...

Advantages and drawbacks of Thiol-ene based resins for 3D-printing

Science.gov (United States)

Leonards, Holger; Engelhardt, Sascha; Hoffmann, Andreas; Pongratz, Ludwig; Schriever, Sascha; Bläsius, Jana; Wehner, Martin; Gillner, Arnold

2015-03-01

The technology of 3D printing is conquering the world and awakens the interest of many users in the most varying of applications. New formulation approaches for photo-sensitive thiol-ene resins in combination with various printing technologies, like stereolithography (SLA), projection based printing/digital light processing (DLP) or two-photon polymerization (TPP) are presented. Thiol-ene polymerizations are known for its fast and quantitative reaction and to form highly homogeneous polymer networks. As the resins are locally and temporally photo-curable the polymerization type is very promising for 3D-printing. By using suitable wavelengths, photoinitiator-free fabrication is feasible for single- and two photon induced polymerization. In this paper divinyl ethers of polyethylene glycols in combination with star-shaped tetrathiols were used to design a simple test-system for photo-curable thiol-ene resins. In order to control and improve curing depth and lateral resolution in 3D-polymerization processes, either additives in chemical formulation or process parameters can be changed. The achieved curing depth and resolution limits depend on the applied fabrication method. While two-/multiphoton induced lithography offers the possibility of micron- to sub-micron resolution it lacks in built-up speed. Hence single-photon polymerization is a fast alternative with optimization potential in sub-10-micron resolution. Absorber- and initiator free compositions were developed in order to avoid aging, yellowing and toxicity of resulting products. They can be cured with UV-laser radiation below 300 nm. The development at Fraunhofer ILT is focusing on new applications in the field of medical products and implants, technical products with respect to mechanical properties or optical properties of 3D-printed objects. Recent process results with model system (polyethylene glycol divinylether/ Pentaerithrytol tetrakis (3-mercaptopropionat), Raman measurements of polymer conversion

Heterofunctional Glycopolypeptides by Combination of Thiol-Ene Chemistry and NCA Polymerization.

Science.gov (United States)

Krannig, Kai-Steffen; Schlaad, Helmut

2016-01-01

Glycopolypeptides are prepared either by the polymerization of glycosylated amino acid N-carboxyanhydrides (NCAs) or by the post-polymerization functionalization of polypeptides with suitable functional groups. Here we present a method for the in-situ functionalization and (co-) polymerization of allylglycine N-carboxyanhydride in a facile one-pot procedure, combining radical thiol-ene photochemistry and nucleophilic ring-opening polymerization techniques, to yield well-defined heterofunctional glycopolypeptides.

Continuous Flow Science in an Undergraduate Teaching Laboratory: Photocatalytic Thiol-Ene Reaction Using Visible Light

Science.gov (United States)

Santandrea, Jeffrey; Kairouz, Vanessa; Collins, Shawn K.

2018-01-01

An undergraduate teaching laboratory experiment involving a continuous flow, photocatalytic thiol-ene reaction using visible-light irradiation is described that allows students to explore concepts of green chemistry, photochemistry, photocatalysis, and continuous flow chemistry.

Emplazamiento hacia el ENE del manto de Los Reales (Alpujarrides occidentales: criterios estructurales y de petrofábrica

Directory of Open Access Journals (Sweden)

Tubía, J. M.

1984-08-01

Full Text Available Los Reales nappe rests over Ojén nappe to the North of Sierra Alpujata. The nappe contact zone shows a intense plastic deformation with mylonitic rocks, The deformation decreases progressively going away from the contacto The structural study of footwall and hangingwall roen permits to attribute this deformation to the Los Reales nappe emplacement over that of Ojén. The foliation and stretching lineation distributions show a WSW-ENE shear direction. The mylonite microstructural characteristics and the enstatite crystalline preferred orientations in the basal peridotites give a mear sense in according that, Los Reales nappe is displaced, in their present position, from the WSW towards the ENE.

El manto de Los Reales descansa sobre el manto de Ojén, al norte de Sierra Alpujata. La zona de contacto entre mantos exhibe una intensa deformación plástica con rocas miloníticas; la deformación disminuye progresivamente al alejarse del contacto. El estudio estructural de las rocas infra y suprayacentes al contacto permite atribuir esta deformación al emplazamiento del manto de Los Reales sobre el de Ojén. , Las distribuciones de la foliación y de la lineación, de estiramiento indican una dirección de cizallamiento WSW-ENE. Las características microestructurales de las milonitas y las orientaciones preferentes cristalinas de la enstatita en las peridotitas basales proporcionan un sentido de cizallamiento tal que el manto de Los Reales se ha desplazado, en su posición actual, desde el WSW hacia el ENE.

Vaesus ja ebavõrdsus = Poverty and inequality / Mari Kreitzberg, Ene-Margit Tiit

Index Scriptorium Estoniae

Kreitzberg, Mari

2004-01-01

Vaesuse ja ühiskonna sotsiaalsest sidususest, vaesuse määratlemisest, subjektiivsest vaesusest, sissetuleku- ja kuluvaesusest, vaesuspiirist, absoluutsest ning suhtelisest vaesusest. Diagrammid. Tabelid. Graafikud

Efforts toward rapid construction of the cortistatin A carbocyclic core via enyne-ene metathesis

KAUST Repository

Baumgartner, Corinne; Ma, Sandy; Liu, Qi; Stoltz, Brian M.

2010-01-01

Our efforts toward the construction of the carbocylic core of cortistatin A via an enyne-ene metathesis are disclosed. Interestingly, an attempted S N2 inversion of a secondary mesylate in our five-membered D-ring piece gave a product with retention

Preparation and Characterization of Fluorinated Hydrophobic UV-Crosslinkable Thiol-Ene Polyurethane Coatings

OpenAIRE

Wenjing Xia; Nianqing Zhu; Rongjie Hou; Wengui Zhong; Mingqing Chen

2017-01-01

The polyurethane prepolymer terminated with a double bond was synthesized using isophorone diisocyanate (IPDI), hydroxyl terminated polybutadiene (HTPB), 1,4-butanediol (BDO), and 2-hydroxyethyl acrylate (HEA). Then, a series of innovative UV-curable polyurethane coatings were prepared by blending ene-terminated polyurethane, fluoroacrylate monomer, and multifunctional thiol crosslinker upon UV exposure. The incorporation of fluoroacrylate monomer and multifunctional thiols into polyurethane ...

High performance thiol-ene thermosets based on fully bio-based poly(limonene carbonate)s

NARCIS (Netherlands)

Li, C.; Johansson, M.; Sablong, R.J.; Koning, C.E.

2017-01-01

High glass transition temperature (Tg) thiol-ene networks (TENs) based on poly(limonene carbonate)s (PLCs), derived from orange oils and of potential degradability are described here. PLCs with moderate molecular weight were prepared by copolymerization of limonene oxide with CO2 and subsequent

ENED-GEM: A Conceptual Framework Model for Psychological Enjoyment Factors and Learning Mechanisms in Educational Games about the Environment

Science.gov (United States)

Fjællingsdal, Kristoffer S.; Klöckner, Christian A.

2017-01-01

Based on a thorough review of psychological literature, this article seeks to develop a model of game enjoyment and environmental learning (ENvironmental EDucational Game Enjoyment Model, ENED-GEM) and delineate psychological processes that might facilitate learning and inspire behavioral change from educational games about the environment. A critically acclaimed digital educational game about environmental issues (Fate of the World by Red Redemption/Soothsayer Games) was used as a case study. Two hundred forty-nine reviews of the game from the popular gaming and reviewing platform known as Steam were analyzed by means of a thematic content analysis in order to identify key player enjoyment factors believed to be relevant to the process of learning from games, as well as to gain an understanding of positive and negative impressions about the game’s general content. The end results of the thematic analysis were measured up to the suggested ENED-GEM framework. Initial results generally support the main elements of the ENED-GEM, and future research into the importance of these individual core factors is outlined. PMID:28701988

ENED-GEM: A Conceptual Framework Model for Psychological Enjoyment Factors and Learning Mechanisms in Educational Games about the Environment

Directory of Open Access Journals (Sweden)

Kristoffer S. Fjællingsdal

2017-06-01

Full Text Available Based on a thorough review of psychological literature, this article seeks to develop a model of game enjoyment and environmental learning (ENvironmental EDucational Game Enjoyment Model, ENED-GEM and delineate psychological processes that might facilitate learning and inspire behavioral change from educational games about the environment. A critically acclaimed digital educational game about environmental issues (Fate of the World by Red Redemption/Soothsayer Games was used as a case study. Two hundred forty-nine reviews of the game from the popular gaming and reviewing platform known as Steam were analyzed by means of a thematic content analysis in order to identify key player enjoyment factors believed to be relevant to the process of learning from games, as well as to gain an understanding of positive and negative impressions about the game’s general content. The end results of the thematic analysis were measured up to the suggested ENED-GEM framework. Initial results generally support the main elements of the ENED-GEM, and future research into the importance of these individual core factors is outlined.

ENED-GEM: A Conceptual Framework Model for Psychological Enjoyment Factors and Learning Mechanisms in Educational Games about the Environment.

Science.gov (United States)

Fjællingsdal, Kristoffer S; Klöckner, Christian A

2017-01-01

Based on a thorough review of psychological literature, this article seeks to develop a model of game enjoyment and environmental learning (ENvironmental EDucational Game Enjoyment Model, ENED-GEM) and delineate psychological processes that might facilitate learning and inspire behavioral change from educational games about the environment. A critically acclaimed digital educational game about environmental issues (Fate of the World by Red Redemption/Soothsayer Games) was used as a case study. Two hundred forty-nine reviews of the game from the popular gaming and reviewing platform known as Steam were analyzed by means of a thematic content analysis in order to identify key player enjoyment factors believed to be relevant to the process of learning from games, as well as to gain an understanding of positive and negative impressions about the game's general content. The end results of the thematic analysis were measured up to the suggested ENED-GEM framework. Initial results generally support the main elements of the ENED-GEM, and future research into the importance of these individual core factors is outlined.

Lift 11 paneb arhitektid ja kunstnikud linna arendama / Oliver Õunmaa

Index Scriptorium Estoniae

Õunmaa, Oliver

2011-01-01

Kultuuripealinna programmi raames maist septembrini Tallinna avalikus ruumis toimuvast linnainstallatsioonide festivalist "Lift11". Kuraatorid Margit Aule, Margit Argus, Maarin Mürk, Ingrid Ruudi. Ideekonkursile esitatud 129 teosest valiti teostamiseks 17 installatsiooni. Tutvustab Margit Aule

Efforts toward rapid construction of the cortistatin A carbocyclic core via enyne-ene metathesis

KAUST Repository

Baumgartner, Corinne

2010-01-01

Our efforts toward the construction of the carbocylic core of cortistatin A via an enyne-ene metathesis are disclosed. Interestingly, an attempted S N2 inversion of a secondary mesylate in our five-membered D-ring piece gave a product with retention of stereochemistry. © 2010 The Royal Society of Chemistry.

Amino acid-incorporated polymer network by thiol-ene polymerization

Directory of Open Access Journals (Sweden)

R. Yokose

2015-08-01

Full Text Available Triallyl L-alanine (A3A and triallyl L-phenylalanine (A3F were synthesized by reactions of L-alanine and L-phenylalanine with allyl bromide in the presence of sodium hydroxide, respectively. Thiol-ene thermal polymerization of A3A or A3F with pentaerythritol-based primary tetrathiol (pS4P or pentaerythritol-based secondary tetrathiol (S4P at allyl/SH 1/1 in the presence of 2,2'-azobis(isobutyronitrile produced an amino acid-incorporated polymer network (A3ApS4P, A3A-S4P or A3F-S4P. Although the thermally cured resins were homogeneous and flat films, the corresponding thiol-ene photopolymerization did not give a successful result. Degree of swelling for each thermally cured film in N,Ndimethylformamide was much higher than that in water. The glass transition and 5% weight loss temperatures (Tg and T5 of A3F-pS4P and A3F-S4P were higher than those of A3A-pS4P and A3A-S4P, respectively. Also, A3F-pS4P and A3F-S4P exhibited much higher tensile strengths and moduli than A3A-pS4P and A3A-S4P did, respectively. Consequently, A3FpS4P displayed the highest Tg (38.7°C, T5 (282.0°C, tensile strength (9.5 MPa and modulus (406 MPa among all the thermally cured resins.

Ene-Liis Semper : Kohalolu piiritsoonis = Presence in the border zone / Anu Allas

Index Scriptorium Estoniae

Allas, Anu, 1977-

2007-01-01

Teatri- ja videokunstnik Ene-Liis Semperi peamiselt 1990-ndate aastate videotest, mis on valdavalt rõhutatult lavastuslikud, paisutatult sümbolistlikud või kus on esitatud piirsituatsioone, ahistust ning selle teadlikku eksponeerimist väljakutsena publikule. Iseennast paljastades, alandades ja ohtu seades jääb kunstnik enamasti jahedalt distantseerituks, publikule jääb aga arusaamatuks, kas tegemist on ohvri, kangelanna või osava mänguriga

Midigraafika Linnagaleriis / Piret Pert

Index Scriptorium Estoniae

Pert, Piret

2001-01-01

Pärnu Linnagaleriis 28. juulini avatud rahvusvahelise väikegraafika näitusest "Midigrafik II". Leedu kunstniku Mikolajus Vilutise, Anu Kalmu, Helje Eelma-Saare, Sirje Eelma, Ülle Marksi ja Jüri Kassi tööde valjapanekust

1-Methoxy-3-o-tolylbicyclo[2.2.2]oct-5-ene-2,2-dicarbonitrile

Directory of Open Access Journals (Sweden)

Orhan Büyükgüngör

2009-09-01

Full Text Available In the title compound, C18H18N2O, the cyclohexene and cyclohexane rings of the bicyclo[2.2.2]oct-5-ene unit adopt distorted boat conformations. In the crystal, molecules exist as C—H...N hydrogen-bonded centrosymmetric R22(14 dimers, which are further linked by C—H...π interactions.

Thiol-Ene Photo-Click Collagen-PEG Hydrogels: Impact of Water-Soluble Photoinitiators on Cell Viability, Gelation Kinetics and Rheological Properties

Directory of Open Access Journals (Sweden)

Róisín Holmes

2017-06-01

Full Text Available Thiol-ene photo-click hydrogels were prepared via step-growth polymerisation using thiol-functionalised type-I collagen and 8-arm poly(ethylene glycol norbornene-terminated (PEG-NB, as a potential injectable regenerative device. Type-I collagen was thiol-functionalised by a ring opening reaction with 2-iminothiolane (2IT, whereby up to 80 Abs.% functionalisation and 90 RPN% triple helical preservation were recorded via 2,4,6-Trinitrobenzenesulfonic acid (TNBS colorimetric assay and circular dichroism (CD. Type, i.e., either 2-Hydroxy-1-[4-(2-hydroxyethoxy phenyl]-2-methyl-1-propanone (I2959 or lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP, and concentration of photoinitiator were varied to ensure minimal photoinitiator-induced cytotoxicity and to enable thiol-ene network formation of collagen-PEG mixtures. The viability of G292 cells following 24 h culture in photoinitiator-supplemented media was largely affected by the photoinitiator concentration, with I2959-supplemented media observed to induce higher toxic response (0.1 → 0.5% (w/v I2959, cell survival: 62 → 2 Abs.% compared to LAP-supplemented media (cell survival: 86 → 8 Abs.%. In line with the in vitro study, selected photoinitiator concentrations were used to prepare thiol-ene photo-click hydrogels. Gelation kinetics proved to be largely affected by the specific photoinitiator, with LAP-containing thiol-ene mixtures leading to significantly reduced complete gelation time (τ: 187 s with respect to I2959-containing mixtures (τ: 1683 s. Other than the specific photoinitiator, the photoinitiator concentration was key to adjusting the hydrogel storage modulus (G’, whereby 15-fold G’ increase (232 → 3360 Pa was observed in samples prepared with 0.5% (w/v compared to 0.1% (w/v LAP. Further thiol-ene formulations with 0.5% (w/v LAP and varied content of PEG-NB were tested to prepare photo-click hydrogels with porous architecture, as well as tunable storage modulus (G�

Koolirõõmuta kool on lapsele kui sunnitöö / Ene-Silvia Sarv ; intervjueerinud Karin Klaus

Index Scriptorium Estoniae

Sarv, Ene-Silvia, 1945-

2013-01-01

Intervjuu Pärnus hariduskonverentsil "Õnnelik õpilane, õnnelik õpetaja" esinenud Tallinna ülikooli lektori Ene-Silvia Sarvega, kes rääkis oma ettekandes, milline paistab tänapäeva kool õpilaste silme läbi ja mis mõjutab koolikliimat kõige enam

Helje Kaskel - eesti elu kosultant / Helje Kaskel ; interv. Jüri Laulik

Index Scriptorium Estoniae

Kaskel, Helje

2003-01-01

Saksamaal Berliinis esilinastub pidulikult 13. oktoobril poliitiline põnevusfilm "Balti torm" ("Baltic Storm"), mis kujutab parvlaev "Estonia" hukku. Urmas Alenderi endine abikaasa, kes tegi filmi juures kaasa tõlgi, kosultandi ja näitlejana, räägib filmist ja selle koseptsioonist

Rapid and simple preparation of thiol–ene emulsion-templated monoliths and their application as enzymatic microreactors

Czech Academy of Sciences Publication Activity Database

Lafleur, J. P.; Senkbeil, S.; Novotný, Jakub; Nys, G.; Bøgelund, N.; Rand, K. D.; Foret, František; Kutter, J. P.

2015-01-01

Roč. 15, č. 10 (2015), s. 2162-2172 ISSN 1473-0197 R&D Projects: GA ČR(CZ) GBP206/12/G014 Institutional support: RVO:68081715 Keywords : thiol-enes * mictoreactor * monolith * fabrication * proteins Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 5.586, year: 2015

Kas erivajadustega lapsed saavad õigel ajal abi? / Ene Mägi, Urve Raudsepp-Alt, Ale Sprenk, Peeter Aas

Index Scriptorium Estoniae

2009-01-01

Küsimusele vastavad: Tallinna Ülikooli Kasvatusteaduste Instituudi eri- ja sotsiaalpedagoogika osakonna juhataja Ene Mägi, Tallinna Haridusameti üldhariduse osakonna peaspetsialist Urve Raudsepp-Alt, Krabi põhikooli direktor Ale Sprenk, Põlva Maavalitsuse haridus-, kultuuri- ja sotsiaalosakonna juhataja Peeter Aas

Poly(ethylene glycol)-based thiol-ene hydrogel coatings: curing chemistry, aqueous stability, and potential marine antifouling applications

NARCIS (Netherlands)

Lundberg, P.; Bruin, A.; Klijnstra, J.W.; Nyström, A.M.; Johansson, M.; Malkoch, M.; Hult, A.

2010-01-01

Photocured thiol-ene hydrogel coatings based on poly(ethylene glycol) (PEG) were investigated for marine antifouling purposes. By varying the PEG length, vinylic end-group, and thiol cross-linker, a library of hydrogel coatings with different structural composition was efficiently accomplished, with

Limitations of the Neurological Evolutional Exam (ENE as a motor assessment for first graders Limitações do Exame Neurológico Evolutivo (ENE como um instrumento de avaliação motora para crianças da primeira série

Directory of Open Access Journals (Sweden)

Priscila M. Caçola

2010-10-01

Full Text Available BACKGROUND: Many clinicians and researchers in Brazil consider the Neurological Developmental Exam (NDE, a valid and reliable assessment for Brazilian school-aged children. However, since its inception, several tests have emerged that, according to some researchers, provide more in-depth evaluation of motor ability and go beyond the detection of general motor status (soft neurological signs. OBJECTIVES: To highlight the limitations of the NDE as a motor skill assessment for first graders. METHODS: Thirty-five children were compared on seven selected items of the NDE, seven of the Bruininks-Oseretsky Test (BOT, and seven of the Visual-Motor Integration test (VMI. Participants received a "pass" or "fail" score for each item, as prescribed by the respective test manual. RESULTS: Chi-square and ANOVA results indicated that the vast majority of children (74% passed the NDE items, whereas values for the other tests were 29% (BOT and 20% (VMI. Analysis of specific categories (e.g. visual, fine, and gross motor coordination revealed a similar outcome. CONCLUSIONS: Our data suggest that while the NDE may be a valid and reliable test for the detection of general motor status, its use as a diagnostic/remedial tool for identifying motor ability is questionable. One of our recommendations is the consideration of a revised NDE in light of the current needs of clinicians and researchers.CONTEXTUALIZAÇÃO: Muitos clínicos e pesquisadores brasileiros consideram o Exame Neurológico Evolutivo (ENE, um instrumento válido e confiável para crianças brasileiras em idade escolar. Entretanto, desde a sua criação, surgiram outros testes para uma avaliação mais profunda de habilidade motora, os quais vão além de detectar status motor geral em forma de sinais neurológicos leves. OBJETIVOS: Demonstrar os pontos fracos do ENE como teste de avaliação de habilidade motora para crianças de primeira série. MÉTODOS: Trinta e cinco crianças realizaram 7 itens

A Convergent Enantioselective Total Synthesis of (-)-Perhydrohistrionicotoxin with an Intramolecular Imino Ene-type Reaction as a Key Step

DEFF Research Database (Denmark)

Tanner, David Ackland; Hagberg, Lars

1998-01-01

A convergent enantioselective total synthesis of the neurotoxic spirocyclic alkaloid (-)-perhydrohistrionicotoxin (2) is described. A Lewis acid-mediated intramolecular imine ene-type reaction was used for the key spirocyclisation step (14 to 3, with 3 being obtained as a single diastereoisomer...

Süütust näpates : Tanel Veenre fotoseeria teatrikostüümidest Draamateatri laval / Tanel Veenre, Hanna Tiidus, Margit Soosaar...[jt.

Index Scriptorium Estoniae

2007-01-01

Stilist: Hanna Tiidus. Naine: Merle Palmiste. Poiss: Joonas (MJ-Models). Kostüümid etendustest "Rohuvoodi" (Aime Unt), "Rehepapp", "Tõeline inspektor koer" (Ene-Liis Semper), "Liilia" (Lilja Blumenfeld), "Mort" (Kersti Varrak), "Potilaadale" (Reet Aus), "Amadeus" (Krista Tool)

Draama 2007. Töörahu / Ene Paaver

Index Scriptorium Estoniae

Paaver, Ene, 1963-

2008-01-01

Ülevaade 2007. aasta eesti draamast. Pikemalt käsitletakse järgmisi autoreid ja nende näidendeid: Mart Kivastik "Tõnu võitlused", Mart Kivastik "Eesti asi", Mart Kivastik "Sõdur", Mart Kivastik "Kuninga viimane lahing ja ülikooli algus", Mart Kivastik, "Nokia 3310", Andrus Kivirähk "Voldemar", Andrus Kivirähk "Uljas neitsi", Hendrik Toompere "Kommunisti surm", Andres Ehin "Saatuslik kihlvedu ehk Volquin Varbola all", Jan Rahman "Jõujaam", Jaak Kõdar "Muinassaar", Karl Berg "Teekond valguse riiki", Angela Randmets "Lembelood vanas linnas", Toomas Kall "Tähtede sadu", Lauri Vahtre "Muna EÜE", Urmas Espenberg "Kestvad kiiduavaldused", Kalju Saaber "Koduvõõrad", Indrek Hirv "Pauluse kiriku kellad", Katrin Saukas "Võlg", Heidi Sarapuu "Austatud Riigikogu liikmed!", Heidi Sarapuu "Helisev viis", Heidi Sarapuu "Ankur hiivata", Jakob Karu "Vanaema juures", Jim Ashilevi "Nagu poisid vihma käes", Jim Ashilevi "Portselansuits", Eva Koff "Mirr", Jaak Prints "Karaoke", Kati Murutar "Mina, naine!", Ott Aardam "Börs ja Börsitar", Andrus Kivirähk, Jan Rahman, Contra "Kõrts", Mart Kase "Perekond", Villu Tamme "Haned võlgu"; Tiit Ojasoo ja Ene-Liis Semperi "GEP ehk Gorjatshije estonskije parni"

Investigation of curing rates of bio-based thiol-ene films from diallyl 2,5-furandicaboxylate

DEFF Research Database (Denmark)

Larsen, Daniel Bo; Sønderbæk-Jørgensen, Rene; Duus, Jens Ø.

2018-01-01

The bio-based monomer, 2,5-furandicarboxylic acid, has been adapted to classic thiol-ene chemistry by derivatization of the acid with allyl alcohol. This new monomer has allowed for the synthesis of new thermoset systems, capable of forming green, sustainable materials through UV-crosslinking. In......The bio-based monomer, 2,5-furandicarboxylic acid, has been adapted to classic thiol-ene chemistry by derivatization of the acid with allyl alcohol. This new monomer has allowed for the synthesis of new thermoset systems, capable of forming green, sustainable materials through UV......-crosslinking. In this study, the synthesis of the new monomer along with thorough kinetic studies of the new thermoset systems are presented. In order to determine kinetic values for the systems, all reactions have been followed by real-time FT-IR. Initially, a study of three different photoinitiators is performed...... on a classic TEMPIC-TATATO system, in order to determine the superior initiator for the new systems. The new monomer is crosslinked with five different thiol compounds in both stoichiometric and off-stoichiometric ratios, yielding an array of bio-based thermosets. The properties of these systems are determined...

Assessment of the role of in situ generated (E)-2,4-diene-valproic acid in the toxicity of valproic acid and (E)-2-ene-valproic acid in sandwich-cultured rat hepatocytes

Energy Technology Data Exchange (ETDEWEB)

Surendradoss, Jayakumar; Chang, Thomas K.H.; Abbott, Frank S., E-mail: frank.abbott@ubc.ca

2012-11-01

Valproic acid (VPA) undergoes cytochrome P450-mediated desaturation to form 4-ene-VPA, which subsequently yields (E)-2,4-diene-VPA by β-oxidation. Another biotransformation pathway involves β-oxidation of VPA to form (E)-2-ene-VPA, which also generates (E)-2,4-diene-VPA by cytochrome P450-mediated desaturation. Although the synthetic form of (E)-2,4-diene-VPA is more hepatotoxic than VPA as shown in various experimental models, there is no conclusive evidence to implicate the in situ generated (E)-2,4-diene-VPA in VPA hepatotoxicity. The present study investigated the effects of modulating the in situ formation of (E)-2,4-diene-VPA on markers of oxidative stress (formation of 2′,7′-dichlorofluorescein; DCF), steatosis (accumulation of BODIPY 558/568 C{sub 12}), necrosis (release of lactate dehydrogenase; LDH), and on cellular total glutathione (GSH) levels in sandwich-cultured rat hepatocytes treated with VPA or (E)-2-ene-VPA. Treatment with either of these chemicals alone increased each of the toxicity endpoints. In VPA-treated hepatocytes, (E)-2,4-diene-VPA was detected only at trace levels, even after phenobarbital (PB) pretreatment and there was no effect on the toxicity of VPA. Furthermore, pretreatment with a cytochrome P450 enzyme inhibitor, 1-aminobenzotriazole (1-ABT), did not influence the extent of VPA toxicity in both PB-pretreated and vehicle-pretreated hepatocytes. However, in (E)-2-ene-VPA-treated hepatocytes, PB pretreatment greatly enhanced the levels of (E)-2,4-diene-VPA and this was accompanied by a further enhancement of the effects of (E)-2-ene-VPA on DCF formation, BODIPY accumulation, LDH release, and GSH depletion. Pretreatment with 1-ABT reduced the concentrations of (E)-2,4-diene-VPA and the extent of (E)-2-ene-VPA toxicity; however, this occurred in PB-pretreated hepatocytes, but not in control hepatocytes. In conclusion, in situ generated (E)-2,4-diene-VPA is not responsible for the hepatocyte toxicity of VPA, whereas it

Ene-Liis Semper: selle aasta puhkepäevad võib ühe käe sõrmedel kokku lugeda

Index Scriptorium Estoniae

Semper, Ene-Liis, 1969-

2011-01-01

Tallinna kultuuripealinna projekti panustanud Ene-Liis Semper võtab 2011. aasta sündmused kokku ja selgitab, kuidas jõudsid publiku ette suurlavastused "The Rise and Fall of Estonia", "Three Kingdoms", Põhuteater ning isikunäitus Kumus

Hydrophobic thiol-ene surfaces fabricated via plasma activation and photo polymerization

Science.gov (United States)

Champathet, P.; Ervithayasuporn, V.; Osotchan, T.; Dangtip, S.

2017-09-01

Alumina, such as glazed alumina for electrical insulator, operated in an open field subjects to a very harsh condition; resulting in lifetime shortening. Coating hydrophobic layer on alumina surface can help prolonging its lifetime. In this study, 25 ×25 mm alumina sheets were used as substrates. The hydrophobic composite polymers were prepared from (3-mercaptopropyl)trimethoxysilane(MPTMS), 2,4,6,8-tetramethyl-2,4,6,8tetravinylcyclotetra siloxane(TMTVSi), pentaerythritoltetra(3-mercaptopropionate)(PETMP), 2,2-dimethoxy-2-phe nylaceto phenone(photoinitiator) and heptadecafluorodecylmethacrylate(HEFDMA) via the thiol-ene reaction. The alumina sheets were first activated by dielectric-barrier discharge plasma to improve its adhesion. All the polymers were found to optimize at the ratio of (MPTMS:TMTVSi:PETMP:HDFDMA) to 4:2:1:2 for coating on the alumina substrate. To enhance polymerization, 2,2-dimethoxy-2-phenylaceto phenome was also used as a photoinitiator A proper mixing sequence in the thiol-ene reaction results in film with excellent surface retention after prolong soaking in solvent such as acetone. FTIR shows that S-H and C=C functional groups have significantly changed after photopolymerization and thermally cured. The static contact angle increase from mere 53.0°±1.5° of the uncoated substrate to 120.0°±1.2° after coating. SEM shows the film with clear appearance of a few-micron thick. Under AFM, the coated surface roughness was about 9.3 nm with evenly distributed spikes of a few nanometer in height. The cross-cut test also confirmed the film was very smooth and none of the square of the films detached.

Mida teie oma tervise heaks teete? / Ly Jagor, Ülle Mihhailova, Ene Pill, Katrin Käbin...[jt.

Index Scriptorium Estoniae

2008-01-01

Küsimusele vastavad Pärnu Õppenõustamiskeskuse psühholoog Ly Jagor, Maasika lasteaia juhataja asetäitja Ülle Mihhailova, Tallinna Perekeskuse ja Tähetorni lastekeskuse psühholoog Ene Pill, Tallinna Nõmme Noortemaja väikelaste ringijuht Katrin Käbin, Tääksi Põhikooli õpetaja Silva Kolk

Ülikooli varakamber = The University Treasury / Mariann Raisma

Index Scriptorium Estoniae

Raisma, Mariann, 1974-

2012-01-01

Tartu Ülikooli Ajaloo muuseumi varakambri sisearhitektuursest lahendusest ja ekspositsiooni kujundusest. Autorid Margit Argus ja Margit Aule. Projekteerija: KAOS Arhitektid. Valmis: 2012. Varakambri museoloogilisest kontseptsioonist

Inorganic-Organic Thiol-ene Coated Mesh for Oil/Water Separation.

Science.gov (United States)

Chen, Qiyi; de Leon, Al; Advincula, Rigoberto C

2015-08-26

A highly efficient mesh for oil/water separation was fabricated by using a superhydrophobic and superoleophilic coating of thiol-ene hybrid, consisting of pentaerythritol tetra(3-mercaptopropionate) (PETMP), 2,4,6,8-tetramethyl-2,4,6,8-tetravinylcyclotetrasiloxane (TMTVSi), and hydrophobic fumed silica nanoparticles, via a simple two-step fabrication process. Spray deposition and UV curing photopolymerization were sequentially performed, during which solvent evaporation provides microscale roughness while nanoparticle aggregation forms nanoscale roughness. The hierarchical morphologies were stabilized after UV curing photopolymerization. High contact angle (>150°) and low roll-off angle (<5°) were achieved due to the multiscale roughness structure of the hierarchical morphologies. These coatings also have excellent chemical resistance, as well as temperature and pH stability, after curing.

Estonia huku filmi eesmärk : alustada tuleb uut uurimist / Tarmo Michelson

Index Scriptorium Estoniae

Michelson, Tarmo, 1975-

2002-01-01

Saksamaa toimuvad poliitilise põnevusfilmi "Baltic Storm" võtted. Film mis kujutab parvlaev "Estonia" hukku venelaste vandenõu tulemusena. Produtsendid on Jutta Rabe ja Kaj Holmberg, režissöör Reuben Leder, peaosades Greta Scacchi ja Jürgen Prochnow. Filmivõtetest räägib assistent Helje Kaskel

Thiol-ene thermosets exploiting surface reactivity for layer-by-layer structures and control of penetration depth for selective surface reactivity

DEFF Research Database (Denmark)

Daugaard, Anders Egede; Westh, Andreas; Pereira Rosinha Grundtvig, Ines

Thiol-ene thermosets have been shown to be an efficient platform for preparation of functional polymer surfaces. Especially the effectiveness and versatility of the system has enabled a large variety of network properties to be obtained in a simple and straight-forward way. Due to its selectivity......, various thiols and allyl or other vinyl reactants can be used to obtain either soft and flexible1 or more rigid functional thermosets 2. The methodology permits use of etiher thermal or photochemical conditions both for matrix preparation as well as for surface functionalization. Due to excess reactive...... groups in thµe surface of thiol-ene thermosets, it is possible to prepare surface functional thermosets or to exploit the reactive groups for modular construction and subsequent chemical bonding. Here a different approach preparing monolithic layer-by-layer structures with controlled mechanical...

Ära söö kiles saia ehk kas poliitilist kunsti on võimalik mõista? = Do not eat white bread in plastic, or is it possible to understand political art? / Ene-Liis Semper, Eero Epner

Index Scriptorium Estoniae

Semper, Ene-Liis, 1969-

2006-01-01

Poliitillisest teatrist. NO99 lavastusest "Nafta" (lavastajad, autorid: Tiit Ojasoo, Ene-Liis Semper, kunstnik Ene-Liis Semper). Ettekanne Kaasaegse Kunsti Eesti Keskuse 4. ettekannete päeval "Kunstnike moraalsed valikud kultuurikonfliktides" Tallinna Kunstihoones 27.04.2006. Bibliograafia lk. 112

3-(2-Benzofuranyl)quinuclidin-2-ene derivatives: novel muscarinic antagonists.

Science.gov (United States)

Nordvall, G; Sundquist, S; Johansson, G; Glas, G; Nilvebrant, L; Hacksell, U

1996-08-16

A series of 26 derivatives of the novel muscarinic antagonist 3-(2-benzofuranyl)quinuclidin-2-ene (1) has been synthesized and evaluated for muscarinic and antimuscarinic properties. The affinity of the compounds was determined by competition experiments in homogenates of cerebral cortex, heart, parotid gland, and urinary bladder from guinea pigs using (-)-[3H]-3-quinuclidinyl benzilate as the radioligand, and the antimuscarinic-potency was determined in a functional assay on isolated guinea pig urinary bladder using carbachol as the agonist. The 5-fluorobenzofuranyl derivative was slightly more potent than 1. The 7-bromo-substituted 8 displayed a 14-fold tissue selectivity ratio for muscarinic receptors in the cortex versus the parotid gland. Comparative molecular field analysis and quantitative structure-activity relationship models were developed for this series of substituted benzofuranyl derivatives.

Tartu Ülikooli Muuseumi varakamber = Treasury of the University of Tartu Museum

Index Scriptorium Estoniae

2015-01-01

Tartu Ülikooli Muuseumi varakamber Lossi tänav 25, valminud 2012. Arhitektuuri sihtkapitali sisearhitektuuripreemia 2012 minevikust tulevikku vaatava efektse ja noorusliku ekspositsiooniruumi kujundamise eest. Sisearhitektid Margit Argus, Margit Aule (KAOS Arhitektid)

Kohtla "majamasin" = Kohtla's Mining-Machine / Kaisa Kaer

Index Scriptorium Estoniae

Kaer, Kaisa

2013-01-01

Kohtla kaevanduspark Ida-Virumaal. Projekteerijad: Arden Arroval, Joonas Sarapuu / Innopolis Insenerid OÜ. Ekspositsiooni kujundus, sisekujundus ja asendiplaan: Margit Argus, Margit Aule / KAOS Arhitektid. 2014. a. valmib endise rikastusvabriku hoones maapealne külastuskeskus

Sõmeru keskusehoone = Sõmeru community centre

Index Scriptorium Estoniae

2011-01-01

Sõmeru alevikus Kooli 2 asuva Sõmeru keskusehoone arhitektuursest lahendusest ja sisekujundusest. Autorid Kristiina Arusoo, Karli Luik, Ralf Lõoke, Maarja Kask (Salto AB), Margit Argus. Loetletud AB Salto ja Margit Arguse tehtud töid

Biocatalysis with thermostable enzymes: structure and properties of a thermophilic 'ene'-reductase related to old yellow enzyme.

Science.gov (United States)

Adalbjörnsson, Björn V; Toogood, Helen S; Fryszkowska, Anna; Pudney, Christopher R; Jowitt, Thomas A; Leys, David; Scrutton, Nigel S

2010-01-25

We report the crystal structure of a thermophilic "ene" reductase (TOYE) isolated from Thermoanaerobacter pseudethanolicus E39. The crystal structure reveals a tetrameric enzyme and an active site that is relatively large compared to most other structurally determined and related Old Yellow Enzymes. The enzyme adopts higher order oligomeric states (octamers and dodecamers) in solution, as revealed by sedimentation velocity and multiangle laser light scattering. Bead modelling indicates that the solution structure is consistent with the basic tetrameric structure observed in crystallographic studies and electron microscopy. TOYE is stable at high temperatures (T(m)>70 degrees C) and shows increased resistance to denaturation in water-miscible organic solvents compared to the mesophilic Old Yellow Enzyme family member, pentaerythritol tetranitrate reductase. TOYE has typical ene-reductase properties of the Old Yellow Enzyme family. There is currently major interest in using Old Yellow Enzyme family members in the preparative biocatalysis of a number of activated alkenes. The increased stability of TOYE in organic solvents is advantageous for biotransformations in which water-miscible organic solvents and biphasic reaction conditions are required to both deliver novel substrates and minimize product racemisation.

Hydrophobic Coatings by Thiol-Ene Click Functionalization of Silsesquioxanes with Tunable Architecture.

Science.gov (United States)

Dirè, Sandra; Bottone, Davide; Callone, Emanuela; Maniglio, Devid; Génois, Isabelle; Ribot, François

2017-08-08

The hydrolysis-condensation of trialkoxysilanes under strictly controlled conditions allows the production of silsesquioxanes (SSQs) with tunable size and architecture ranging from ladder to cage-like structures. These nano-objects can serve as building blocks for the preparation of hybrid organic/inorganic materials with selected properties. The SSQs growth can be tuned by simply controlling the reaction duration in the in situ water production route (ISWP), where the kinetics of the esterification reaction between carboxylic acids and alcohols rules out the extent of organosilane hydrolysis-condensation. Tunable SSQs with thiol functionalities (SH-NBBs) are suitable for further modification by exploiting the simple thiol-ene click reaction, thus allowing for modifying the wettability properties of derived coatings. In this paper, coatings were prepared from SH-NBBs with different architecture onto cotton fabrics and paper, and further functionalized with long alkyl chains by means of initiator-free UV-induced thiol-ene coupling with 1-decene (C10) and 1-tetradecene (C14). The coatings appeared to homogeneously cover the natural fibers and imparted a multi-scale roughness that was not affected by the click functionalization step. The two-step functionalization of cotton and paper warrants a stable highly hydrophobic character to the surface of natural materials that, in perspective, suggests a possible application in filtration devices for oil-water separation. Furthermore, the purification of SH-NBBs from ISWP by-products was possible during the coating process, and this step allowed for the fast, initiator-free, click-coupling of purified NBBs with C10 and C14 in solution with a nearly quantitative yield. Therefore, this approach is an alternative route to get sol-gel-derived, ladder-like, and cage-like SSQs functionalized with long alkyl chains.

Fabrication of antibody-loaded microgels using microfluidics and thiol-ene photoclick chemistry.

Science.gov (United States)

Gregoritza, Manuel; Abstiens, Kathrin; Graf, Moritz; Goepferich, Achim M

2018-06-01

Reducing burst effects, providing controlled release, and safeguarding biologics against degradation are a few of several highly attractive applications for microgels in the field of controlled release. However, the incorporation of proteins into microgels without impairing stability is highly challenging. In this proof of concept study, the combination of microfluidics and thiol-ene photoclick chemistry was evaluated for the fabrication of antibody-loaded microgels with narrow size distribution. Norbornene-modified eight-armed poly(ethylene glycol) with an average molecular mass of 10,000 Da, 20,000 Da, or 40,000 Da were prepared as macromonomers for microgel formation. For functionalization, either hydrolytically cleavable ester or stable amide bonds were used. A microfluidic system was employed to generate precursor solution droplets containing macromonomers, the cross-linker dithiothreitol and the initiator Eosin-Y. Irradiation with visible light was used to trigger thiol-ene reactions which covalently cross-linked the droplets. For all bond-types, molecular masses, and concentrations gelation was very rapid (<20 s) and a plateau for the complex shear modulus was reached after only 5 min. The generated microgels had a rod-like shape and did not show considerable cellular toxicity. Stress conditions during the fabrication process were simulated and it could be shown that fabrication did not impair the activity of the model proteins lysozyme and bevacizumab. It was confirmed that the average hydrogel network mesh size was similar or smaller than the hydrodynamic diameter of bevacizumab which is a crucial factor for restricting diffusion and delaying release. Finally, microgels were loaded with bevacizumab and a sustained release over a period of 30 ± 4 and 47 ± 7 days could be achieved in vitro. Copyright © 2018 Elsevier B.V. All rights reserved.

Katkenud õpingute teise kõrgkooli "kolimine" nõuab visadust / Agne Narusk, Ene Küüner, Heli Mattisen, Kadri Osula

Index Scriptorium Estoniae

Narusk, Agne

2007-01-01

Pooleli jäänud ülikooliõpingute lõpetamisest. Varasemate õpingute ja töökogemuse arvestamise tingimusi õpingute jätkamisel selgitavad Tartu Ülikooli avatud ülikooli tasemeõppe koordinaator Ene Küüner, Tallinna Ülikooli akadeemiline prorektor Heli Mattisen ja Estonian Business Schoolì õppeosakonna juhataja Kadri Osula

Eesti Ajaloomuuseum = Estonian History Museum

Index Scriptorium Estoniae

2012-01-01

Renoveeritud Eesti Ajaloomuuseumi Suurgildi hoone sisekujundusest ja ekspositsioonist. Sisekujundusprojekti autorid: Margit Aule (KAOS Arhitektid), Liis Lindvere (KOKO Arhitektid) ja Margit Argus (KAOS Arhitektid), loetletud nende töid. Suure saali metallpõranda autorid: Risto Tali, Rait Siska

A neutral polyacrylate copolymer coating for surface modification of thiol-ene microchannels for improved performance of protein separation by microchip electrophoresis

DEFF Research Database (Denmark)

Mesbah, Kiarach; Mai, T.D.; Jensen, Thomas Glasdam

2016-01-01

We have investigated the behavior of thiol-ene substrates that is a class of promising materials for lab-on-a-chip electrophoresis applications. Two polymeric materials were prepared by copolymerization of N, N-dimethylacrylamide (DMA), (3-(methacryloyl-oxy)propyl)trimethoxysilane (PMA) and 3-tri...

Selective fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene by nucleotides.

Science.gov (United States)

Marquez, Cesar; Pischel, Uwe; Nau, Werner M

2003-10-16

[reaction: see text] The fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) by nucleotides has been studied. The quenching mechanism was analyzed on the basis of deuterium isotope effects, tendencies for exciplex formation, and the quenching efficiency in the presence of a molecular container (cucurbit[7]uril). Exciplex-induced quenching appears to prevail for adenosine, cytidine, and uridine, while hydrogen abstraction becomes competitive for thymidine and guanosine. Compared to other fluorescent probes, DBO responds very selectively to the type of nucleotide.

Lift11 / Ingrid Ruudi

Index Scriptorium Estoniae

Ruudi, Ingrid, 1978-

2010-01-01

23. augustist 11. oktoobrini 2010 toimuvast konkursist, mille eesmärk on leida kultuuripealinna üritusena toimuva linnainstallatsioonide festivali "Lift11" tarvis installatsioonide ideekavandeid. Festivali kuraatorid on kunstiteadlased Maarin Mürk ja Ingrid Ruudi ning arhitektid Margit Aule ja Margit Argus

Thiol-ene click chemistry derived cationic cyclodextrin chiral stationary phase and its enhanced separation performance in liquid chromatography.

Science.gov (United States)

Yao, Xiaobin; Tan, Timothy Thatt Yang; Wang, Yong

2014-01-24

This work is the first demonstration of a simple thiol-ene click chemistry to anchor vinyl imidazolium β-CD onto thiol silica to form a novel cationic native cyclodextrin (CD) chiral stationary phase (CSP). The CSP afforded high enantioseparation ability towards dansyl (Dns) amino acids, carboxylic aryl compounds and flavonoids in chiral HPLC. The current CSP demonstrates the highest resolving ability (selectivity >1.1, resolution >1.5) towards Dns amino acids in a mobile phase buffered at pH=6.5, with the resolution of Dns-dl-leucine as high as 6.97. 2,4-dichloride propionic acid (2,4-ClPOPA) was well resolved with the selectivity and resolution of 1.37 and 4.88, respectively. Compared to a previously reported native CD-CSP based on a triazole linkage, the current cationic CD-CSP shows a stronger retention and higher resolution towards acidic chiral compounds, ascribed to the propitious strong electrostatic attraction. Stability evaluation results indicated that thiol-ene reaction can provide a facile and robust approach for the preparation of positively charged CD CSPs. Copyright © 2013 Elsevier B.V. All rights reserved.

Functional characterization and stability improvement of a ‘thermophilic-like’ ene-reductase from Rhodococcus opacus 1CP

Directory of Open Access Journals (Sweden)

Anika eRiedel

2015-10-01

Full Text Available Ene-reductases are widely applied for the asymmetric synthesis of relevant industrial chemicals. A novel ene-reductase OYERo2 was found within a set of 14 putative Old Yellow Enzymes (OYEs obtained by genome mining of the actinobacterium Rhodococcus opacus 1CP. Multiple sequence alignment suggested that the enzyme belongs to the group of ‘thermophilic-like’ OYEs. OYERo2 was produced in Escherichia coli and biochemically characterized. The enzyme is strongly NADPH dependent and uses non-covalently bound FMNH2 for the reduction of activated α,β-unsaturated alkenes. In the active form OYERo2 is a dimer. Optimal catalysis occurs at pH 7.3 and 37 °C. OYERo2 showed highest specific activities (4550 U mg-1 on maleimides, which are efficiently converted to the corresponding succinimides. The OYERo2-mediated reduction of prochiral alkenes afforded the (R-products with excellent optical purity (ee > 99%. OYERo2 is not as thermo-resistant as related OYEs. Introduction of a characteristic intermolecular salt bridge by site-specific mutagenesis raised the half-life of enzyme inactivation at 32 °C from 28 min to 87 min and improved the tolerance towards organic co-solvents. The suitability of OYERo2 for application in industrial biocatalysis is discussed.

Polysiloxane-based luminescent elastomers prepared by thiol-ene "click" chemistry.

Science.gov (United States)

Zuo, Yujing; Lu, Haifeng; Xue, Lei; Wang, Xianming; Wu, Lianfeng; Feng, Shengyu

2014-09-26

Side-chain vinyl poly(dimethylsiloxane) has been modified with mercaptopropionic acid, methyl 3-mercaptopropionate, and mercaptosuccinic acid. Coordinative bonding of Eu(III) to the functionalized polysiloxanes was then carried out and crosslinked silicone elastomers were prepared by thiol-ene curing reactions of these composites. All these europium complexes could be cast to form transparent, uniform, thin elastomers with good flexibility and thermal stability. The networks were characterized by FTIR, NMR, UV/Vis, and luminescence spectroscopy as well as by scanning electron microscopy, thermogravimetric analysis, and X-ray photoelectron spectroscopy. The europium elastomer luminophores exhibited intense red light at 617 nm under UV excitation at room temperature due to the (5)D0 →(7)F2 transition in Eu(III) ions. The newly synthesized luminescent materials offer many advantages, including the desired mechanical flexibility. They cannot be dissolved or fused, and so they have potential for use in optical and electronic applications. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Synthesis of Upconverting Hydrogel Nanocomposites Using Thiol-Ene Click Chemistry: Template for the Formation of Dendrimer-Like Gold Nanoparticle Assemblies.

Science.gov (United States)

Meesaragandla, Brahmaiah; Mahalingam, Venkataramanan

2015-11-16

The synthesis of upconverting hydrogel nanocomposites by base-catalyzed thiol-ene click reaction between 10-undecenoic acid capped Yb(3+)/Er(3+)-doped NaYF4 nanoparticles and pentaerythritol tetrakis(3-mercaptopropionate) (PETMP) as tetrathiol monomer is reported. This synthetic strategy for nanocomposite gels is quite different from works where usually the preformed gels are mixed with the nanoparticles. Developing nanocomposites by surface modification of capping ligands would allow tuning and controlling of the separation of the nanoparticles inside the gel network. The hydrogel nanocomposites prepared by thiol-ene click reaction show strong enhancement in luminescence intensity compared to 10-undecenoic acid-capped Yb(3+)/Er(3+)-doped NaYF4 nanoparticles through the upconversion process (under 980 nm laser excitation). The hydrogel nanocomposites display strong swelling characteristics in water resulting in porous structures. Interestingly, the resulting nanocomposite gels act as templates for the synthesis of dendrimer-like Au nanostructures when HAuCl4 is reduced in the presence of the nanocomposite gels. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Lennusadam = Seaplane Harbour / Andrus Kõresaar

Index Scriptorium Estoniae

Kõresaar, Andrus, 1975-

2013-01-01

Tallinna Lennusadama vesilennukite angaaride rekonstrueerimisest, Eesti Meremuuseumi uue ekspositsiooni kujundusest. Autorid: Andrus Kõresaar, Olga Batuhtina, Raivo Kotov, Margit Argus, Margit Aule, Indrek Mikk (KOKO Arhitektid). Insener Karl Õiger. Arhitektuuriajaloolase Mart Kalmu ning arhitektuurikriitiku ja ESLi aastapreemiate žürii liikme Triin Ojari arvamused

Kui oluliseks isikuandmete kaitsmist kooli oludes peate ja millest seda tehes lähtute? / Harri Kõo, Ene Tannberg, Kalle Niinas, Maria Tiro...[jt.

Index Scriptorium Estoniae

2008-01-01

Küsimusele vastavad Tabasalu Ühisgümnaasiumi direktor Harri Kõo, Tartu Miina Härma Gümnaasiumi direktor Ene Tannberg, Jakob Westholmi Gümnaasiumi direktor Kalle Niinas, Jüri Gümnaasiumi direktor Maria Tiro ja Viimsi Keskkooli direktor Leelo Tiisvelt

Tallinna Teletorn = Tallinn Television Tower

Index Scriptorium Estoniae

2015-01-01

Rekonstrueeritud Tallinna Teletorn Kloostrimetsa tee 58a, valminud 2012. Eesti kultuurkapitali aastapreemia 2012. Arhitekt David Basiladze. Rekonstrueerimise projekti arhitektid Raivo Kotov, Andrus Kõresaar, Indrek Mikk, Margit Aule, Jaanus Männik, Lea Laidra, Karis Kahr (KOKO Arhitektid). Sisearhitektid Liis Lindvere, Raili Paling, Margit Argus (KOKO Arhitektid). Konstruktor Neoprojekt

Kohtumisel Bushiga tuleks tõstatada ka Estonia huku teema / Allar Viivik

Index Scriptorium Estoniae

Viivik, Allar

2006-01-01

Parvlaeval Estonia hukkunute omaste ühendused avaldasid oma pöördumises Toomas Hendrik Ilvesele soovi, et president arutaks kohtumisel USA presidendi George W. Bushiga USA julgeolekuagentuuri NSA käsutuses olevate laevahukku puudutavate salastatud dokumentide üleandmist Eestile. Pöördumisele on alla kirjutanud Estonia Litigation Associationi esimees Helje Kaskel ja Estonia Hukupõhjuste Väljaselgitamise Mittetulundusühingu (EHVM) juht Ülo Veide

(E-2-((4R,5R-5-((Benzyloxymethyl-2,2-dimethyl-1,3-dioxolan-4-ylbut-2-ene-1,4-diol

Directory of Open Access Journals (Sweden)

Carlos R. Carreras

2010-04-01

Full Text Available The synthesis of (E-2-((4R,5R-5-((benzyloxymethyl-2,2-dimethyl-1,3-dioxolan-4-ylbut-2-ene-1,4-diol by a one-step reduction of the appropriate 2-substituted butenolide is reported. Product characterization was carried out by IR, 1H NMR, 13C NMR, MS, elemental analysis and optical rotation.

Novel Anti-Biofouling Soft Contact Lens: l-Cysteine Conjugated Amphiphilic Conetworks via RAFT and Thiol-Ene Click Chemistry.

Science.gov (United States)

Zhang, Chengfeng; Liu, Ziyuan; Wang, Haiye; Feng, Xiaofeng; He, Chunju

2017-07-01

A unique l-cysteine conjugated antifouling amphiphilic conetwork (APCN) is synthesized through end-crosslinking of well-defined triblock copolymers poly(allyl methacrylate)-b-poly(ethylene glycol)-b-poly(allyl methacrylate) via a combination of reversible addition-fragmentation chain transfer (RAFT) polymerization and thiol-ene "click" chemistry. The synthesized poly(ethylene glycol) macro-RAFT agent initiates the polymerization of allyl methacrylate in a controlled manner. The vinyl pendant groups of the precursor partially conjugate with l-cysteine and the rest fully crosslink with mercaptopropyl-containing siloxane via thiol-ene click chemistry under UV irradiation into APCNs, which show distinguished properties, that is, excellent biocompatibility, more than 39.6% water content, 101 barrers oxygen permeability, optimized mechanical properties, and more than 93% visible light transmittance. What's more, the resultant APCNs exhibit eminent resistance to protein adsorption, where the bovine serum albumin and lysozyme adsorption are decreased to 12 and 21 µg cm -2 , respectively. The outstanding properties of APCNs depend on the RAFT controlled method, which precisely designs the hydrophilic/hydrophobic segments and eventually greatly improves the crosslinking efficiency and homogeneity. Meantime, the l-cysteine monolayer can effectively reduce the surface hydrophobicity and prevent protein adsorption, which exhibits the viability for antifouling surface over and under ophthalmic devices, suggesting a promising soft contact lens. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Kadri Mälk ja Just Must / Mirjam Peil

Index Scriptorium Estoniae

Peil, Mirjam, 1939-

2008-01-01

Rahvusvaheline ehtekunstinäitus "Just Must" Eesti Ajaloomuuseumi Suurgildi hoones, kuraator Kadri Mälk ja kujundaja Taso Mähar. Osalesid 59 kunstnikku 18 riigist. Näitusega kaasneb Aadam Kaarma kujundatud kataloog. 10 fotot ehetest

Eesti Filharmoonia Kammerkoor esineb Eestimaa külades

Index Scriptorium Estoniae

2008-01-01

Reigi ja Emmaste kirikus 6. juunil, Kihelkonna ja Kaarma kirikus 7. juunil, Valjala ja Muhu kirikus 8. juunil, Viimsi Püha Jaakobi kirikus 10. juunil ja Harju-Madise Mattiase kirikus 11. juunil toimuvatest kontsertidest

Eesti kooliõpilaste väärtushinnanguist ja huvialadest / Ingrid Rüütel, Ene-Margit Tiit

Index Scriptorium Estoniae

Rüütel, Ingrid, 1935-

2005-01-01

Artiklis analüüsitakse 2004. a. Eesti koolides läbi viidud ankeetküsitlusi teemal "Kooliõpilaste väärtushinnangud ja huvialad". Küsitleti 12-19-aastasi eestikeelsete koolide õpilasi kogu Eestist. Kokku vastas küsitlusele 345 õpilast

Klubi "Spirit" = Club Spirit / Hanno Soans ; tõlk. Liisi Ojamaa

Index Scriptorium Estoniae

Soans, Hanno, 1974-

2000-01-01

Eesti klubikultuurist 1990-ndatel. Klubi "Spirit" kujundusest. Sisearhitektid Tarmo Piirmets, Martti Siimann. Arhitekt Jüri Irik Arhitektuuribüroost Ehala & Irik. Projekt ja klubi valmis 2000. Flaierid kujundas Aadam Kaarma. 10 ill. Vaated, korruste plaanid

Joint statement of the President, Speaker of the Riigikogu and Prime Minister of the Republic of Estonia / Toomas Hendrik Ilves, Ene Ergma, Andrus Ansip

Index Scriptorium Estoniae

Ilves, Toomas Hendrik, 1953-

2008-01-01

President Toomas Hendrik Ilvese, Riigikogu spiikri Ene Ergma ja peaminister Andrus Ansipi ühisavaldus Teise maailmasõja lõpu 62. aastapäeva puhul 8. mail 2007, milles kinnitatakse, et hoolimata Teise maailmasõja ajaloolistest tõlgendustest on kõik Eestis elavad inimesed vabad ning jagavad ühist tulevikku

Eesti Meremuuseumi hoone Lennusadamas = Estonian Maritime Museum in the Tallinn Seaplane Harbour

Index Scriptorium Estoniae

2015-01-01

Eesti Meremuuseumi rekonstrueeritud vesilennukite angaarid Tallinnas Vesilennuki 6, valminud 2012. Eesti kultuurkapitali aastapreemia 2012. Arhitektid Raivo Kotov, Andrus Kõresaar, Indrek Mikk, Margit Aule, Tõnis Savi, Lea Laidra, Karis Kahr, Jelena Altmäe, Jaanus Männik (KOKO Arhitektid). Sisearhitektid Margit Argus, Andrus Kõresaar, Olga Batuhtina (KOKO Arhitektid). Raudbetoonkonstruktsioonide renoveerimisprojekt Karl Õiger, Heiki Onton (Tallinna Tehnikaülikool). Uued konstruktsioonid Neoprojekt

Facile preparation of organic-silica hybrid monolith for capillary hydrophilic liquid chromatography based on "thiol-ene" click chemistry.

Science.gov (United States)

Chen, Ming-Luan; Zhang, Jun; Zhang, Zheng; Yuan, Bi-Feng; Yu, Qiong-Wei; Feng, Yu-Qi

2013-04-05

In this work, a one-step approach to facile preparation of organic-inorganic hybrid monoliths was successfully developed. After vinyl-end organic monomers and azobisisobutyronitrile (AIBN) were mixed with hydrolyzed tetramethoxysilane (TMOS) and 3-mercaptopropyltrimethoxysilane (MPTMS), the homogeneous mixture was introduced into a fused-silica capillary for simultaneous polycondensation and "thiol-ene" click reaction to form the organic-silica hybrid monoliths. By employing this strategy, two types of organic-silica hybrid monoliths with positively charged quaternary ammonium and amide groups were prepared, respectively. The functional groups were successfully introduced onto the monoliths during the sol-gel process with "thiol-ene" click reaction, which was demonstrated by ζ-potential assessment, energy dispersive X-ray spectroscopy (EDX), and Fourier transform infrared (FT-IR) spectroscopy. The porous structure of the prepared monolithic columns was examined by scanning electron microscopy (SEM), nitrogen adsorption-desorption measurement, and mercury intrusion porosimetry. These results indicate the prepared organic-silica hybrid monoliths possess homogeneous column bed, large specific surface area, good mechanical stability, and excellent permeability. The prepared monolithic columns were then applied for anion-exchange/hydrophilic interaction liquid chromatography. Different types of analytes, including benzoic acids, inorganic ions, nucleosides, and nucleotides, were well separated with high column efficiency around 80,000-130,000 plates/m. Taken together, we present a facile and universal strategy to prepare organic-silica hybrid monoliths with a variety of organic monomers using one-step approach. Copyright © 2013 Elsevier B.V. All rights reserved.

Crystal and Molecular Structure Studies of Ethyl 4-(4-Hydroxyphenyl-6-(6-methoxy-2-naphthyl-2-oxocyclohex-3-ene-1-carboxylate and Ethyl 4-(3-Bromophenyl-6-(6-methoxy-2-naphthyl-2-oxocyclohex-3-ene-1-carboxylate

Directory of Open Access Journals (Sweden)

Badiadka Narayana

2012-08-01

Full Text Available The crystal and molecular structures of the title compounds, ethyl 4-(4-hydroxyphenyl-6-(6-methoxy-2-naphthyl-2-oxocyclohex-3-ene-1-carboxylate (I and ethyl 4-(3-bromophenyl-6-(6-methoxy-2-naphthyl-2-oxocyclohex-3-ene-1-carboxylate (II, are reported and confirmed by single crystal X-ray diffraction data. Compound (I, C26H24O5, crystallizes from a methanol solution in the monoclinic C2/c space group with eight molecules in the unit cell. The unit cell parameters are: a = 25.4114(5 Å, b = 8.47440(10 Å, c = 20.6921(4 Å, β = 108.328(2° and V = 4229.92(13 Å3. Disorder is observed throughout the entire molecule with an occupancy ratio 0.690(2:0.310(2. Compound (II, C26H23O4Br, crystallizes from an ethyl acetate solution in the monoclinic P21/c spacegroup with four molecules in the unit cell. The unit cell parameters are a = 17.8991(9 Å, b = 11.4369(6 Å, c = 10.8507(5 Å, β = 92.428(4° and V = 2219.25(19 Å3. Disorder is observed in the cyclohexenone ring and the carboxylate group with an occupancy ratio 0.830(6:0.170(6. Weak O–H...O (I or C–H...O (II intermolecular interactions are observed which influence crystal packing stability. These chalcone derivative types of molecules are important in their ability to act as activated unsaturated systems in conjugated addition reactions of carbanions in the presence of basic catalysts which exhibit a multitude of biological activities.

Estonia katastroofis hukkunute omaste seisukohad ja palve seoses USA presidendi George W. Bushi visiidiga

Index Scriptorium Estoniae

2006-01-01

Estonia protsessiühingu esimehe Helje Kaskeli ja Estonia Hukupõhjuste Väljaselgitamise Mittetulundusühingu esimehe Ülo Veide pöördumises president Toomas Hendrik Ilvese poole tuuakse esile katastroofis hukkunute omaste seisukohad. Ilmunud ka: Kesknädal 29. nov. 2006, lk. 4-5, pealk.: Ilves, avita! Estonia katastroofis hukkunute omaste palvekiri Toomas Hendrik Ilvesele; Vaba Eesti Sõna 30. nov. 2006, lk. 3, 10, pealk.: Avalik kiri Eesti Vabariigi presidendile Toomas H. Ilvesele

"Ekspeditsioon Wunderlich" = "Expedition Wunderlich" / Carl-Dag Lige, Hannes Praks ; kommenteerinud Triin Ojari

Index Scriptorium Estoniae

Lige, Carl-Dag, 1982-

2016-01-01

Näitus "Ekspeditsioon Wunderlich" Eesti Arhitektuurimuuseumis. Autorid Katrin Talvik, Merilin Tee, Sabine Suuster, Martin Saar, Karl Taul, Alden Jõgisuu, Tõnu Lensment, Aadam Kaarma, Cael-Dag Lige, Hannes Praks. Näitus on Eesti Kunstiakadeemia ja Eesti Arhitektuurimuuseumi ühisprojekt

Synthesis and Transformations of di-endo-3-Aminobicyclo-[2.2.2]oct-5-ene-2-carboxylic Acid Derivatives

Directory of Open Access Journals (Sweden)

Márta Palkó

2011-09-01

Full Text Available all-endo-3-amino-5-hydroxybicyclo[2.2.2]octane-2-carboxylic acid (13 and all-endo-5-amino-6-(hydroxymethylbicyclo[2.2.2]octan-2-ol (10 were prepared via dihydro-1,3-oxazine or g-lactone intermediates by the stereoselective functionalization of an N-protected derivative of endo-3-aminobicyclo[2.2.2]oct-5-ene-2-carboxylic acid (2. Ring closure of b-amino ester 4 resulted in tricyclic pyrimidinones 15 and 16. The structures, stereochemistry and relative configurations of the synthesized compounds were determined by IR and NMR.

Vabariigi presidendi, riigikogu esimehe ja peaministri ühisavaldus 8. mail 2007 / Toomas Hendrik Ilves, Ene Ergma, Andrus Ansip

Index Scriptorium Estoniae

Ilves, Toomas Hendrik, 1953-

2007-01-01

President Toomas Hendrik Ilvese, Riigikogu spiikri Ene Ergma ja peaminister Andrus Ansipi avaldus Teise maailmasõja lõpu 62. aastapäeva puhul. Ilmunud ka: Severnoje Poberežje 9. mai 2007, lk. 2; Eesti Elu 11. mai 2007, lk. 2, pealk.: Riigijuhtide ühisavaldus Teise maailmasõja mälestuspäeval, ingl. k. lk. 11, pealk.: Joint statement May 8, 2007; ingl. k. Vaba Eesti Sõna 10. mai 2007, lk. 12, pealk.: Joint statement of the President, Speaker of the Parliament and Prime Minister of the Republic of Estonia

Münchenis esitletakse Eesti juveelikunsti

Index Scriptorium Estoniae

2009-01-01

Münchenis toimuval üritusel Schmuckzene esitletakse raamatut "Just Must", mis ilmus 2008. aastal Tallinnas samanimelise ehtekunstinäituse raames. Koostaja Kadri Mälk, kujundaja Aadam Kaarma, fotod Tanel Veenre. Kirjastus Arnoldsche Art Publishers arvas raamatu aasta viie parema ehtekunstiraamatu hulka

Iron complexes of tetramine ligands catalyse allylic hydroxyamination via a nitroso–ene mechanism

Directory of Open Access Journals (Sweden)

David Porter

2015-12-01

Full Text Available Iron(II complexes of the tetradentate amines tris(2-pyridylmethylamine (TPA and N,N′-bis(2-pyridylmethyl-N,N′-dimethylethane-1,2-diamine (BPMEN are established catalysts of C–O bond formation, oxidising hydrocarbon substrates via hydroxylation, epoxidation and dihydroxylation pathways. Herein we report the capacity of these catalysts to promote C–N bond formation, via allylic amination of alkenes. The combination of N-Boc-hydroxylamine with either FeTPA (1 mol % or FeBPMEN (10 mol % converts cyclohexene to the allylic hydroxylamine (tert-butyl cyclohex-2-en-1-yl(hydroxycarbamate in moderate yields. Spectroscopic studies and trapping experiments suggest the reaction proceeds via a nitroso–ene mechanism, with involvement of a free N-Boc-nitroso intermediate. Asymmetric induction is not observed using the chiral tetramine ligand (+-(2R,2′R-1,1′-bis(2-pyridylmethyl-2,2′-bipyrrolidine ((R,R′-PDP.

Development of a thiol-ene based screening platform for enzyme immobilization demonstrated using horseradish peroxidase

DEFF Research Database (Denmark)

Hoffmann, Christian; Pinelo, Manuel; Woodley, John

2017-01-01

Efficient immobilization of enzymes on support surfaces requires an exact match between the surface chemistry and the specific enzyme. A successful match would normally be identified through time consuming screening of conventional resins in multiple experiments testing individual immobilization...... strategies. In this study we present a versatile strategy that largely expands the number of possible surface functionalities for enzyme immobilization in a single, generic platform. The combination of many individual surface chemistries and thus immobilization methods in one modular system permits faster...... functionalization by thiol-ene chemistry (TEC) resulted in the formation of a functional monolayer in each well, whereas, polymer surface grafts were introduced through surface chain transfer free radical polymerization (SCT-FRP). Enzyme immobilization on the modified surfaces was evaluated by using a rhodamine...

Facile synthesis of linear-dendritic cholesteryl-poly(epsilon-caprolactone)-b-(L-lysine)(G2) by thiol-ene and azide-alkyne "click" reactions

DEFF Research Database (Denmark)

Javakhishvili, Irakli; Binder, W.H.; Tanner, S.

2010-01-01

The construction of a linear-dendritic block copolymer consisting of terminal cholesteryl moiety, poly(epsilon-caprolactone), and a second generation L-lysine dendron has been accomplished by the combination of copper(I) catalyzed azide-alkyne and UV-triggered thiol-ene "click" reactions. Ring-op...... and thiocholesterol. Near to quantitative functionalization of the intermediate and final products has been attained as confirmed by NMR spectroscopy and MALDI-TOF spectrometry....

Photolithographic fabrication of solid–liquid core waveguides by thiol-ene chemistry

International Nuclear Information System (INIS)

Sagar, Kaushal; Gopalakrishnan, Nimi; Christiansen, Mads Brøkner; Kristensen, Anders; Ndoni, Sokol

2011-01-01

In this work we demonstrate an efficient and cleanroom compatible method for the fabrication of solid–liquid core waveguides based on nanoporous polymers. We have used thiol-ene photo-grafting to tune and pattern the hydrophilicity of an originally hydrophobic nanoporous 1, 2-polybutadiene. The generated refractive index contrast between the patterned water-filled volume and the surrounding empty hydrophobic porous polymer allows for light confinement within the water-filled volume—the solid–liquid core. The presented fabrication process is simple and fast. It allows a high degree of flexibility on the type and grade of surface chemistry imparted to the large nanoporous area depending upon the application. The fabrication does not need demanding chemical reaction conditions. Thus, it can be readily used on a standard silicon lithography bench. The propagation loss values reported in this work are comparable with literature values for state-of-the-art liquid-core waveguide devices. The demonstrated waveguide function added to the nanoporous polymer with a very high internal surface area makes the system interesting for many applications in different areas, such as diagnostics and bio-chemical sensing

Thermal decomposition of lanthanides (III) and yttrium (III) solid complexes from ethyl ene diamine tetraacetic acid

International Nuclear Information System (INIS)

Mercadante, A.

1991-01-01

Solid state compounds of lanthanides (III) and yttrium derived from ethyl ene diamine tetraacetic acid were prepared from respective basic carbonates, that were neutralized with EDTA stoichiometry quantities. Complexometry with EDTA, thermogravimetry (TG), differential thermal analysis (DTA) and X-ray diffraction have been used in the study of these compounds. The results of complexometry with EDTA as well as TG and DTA curves bed to the stoichiometry of these compounds the following general formula is obeyed: H[Ln(EDTA]. n H 2 O. X-ray powder patterns of these compounds permitted to establish two isomorphous series. The DTA ant TG curves allowed us to study the dehydration process, the thermal stability and thermal decomposition of these compounds. (C.G.C.)

Tallinna Kunstihoone, Bajozi Veinikelder ja AS Kiil & Co kuulutasid käesoleva aasta sügisel välja multiplitseeritava kunstiteose

Index Scriptorium Estoniae

2005-01-01

Žürii (liikmed loetletud) valis välja Merike Estna, Maksim Surini, Andres Lõo, Evelin Kuusiku, Kärt Ojavee ja Aadam Kaarma teosed. Auhinnasaajate järjekord ja preemiad tehakse teatavaks konkursitööde näituse "Mitmik" avamisel Tallinna Kunstihoone galeriis 8. XII

Modifying surface resistivity and liquid moisture management property of keratin fibers through thiol-ene click reactions.

Science.gov (United States)

Yu, Dan; Cai, Jackie Y; Church, Jeffrey S; Wang, Lijing

2014-01-22

This paper reports on a new method for improving the antistatic and liquid moisture management properties of keratinous materials. The method involves the generation of thiols by controlled reduction of cystine disulfide bonds in keratin with tris(2-carboxyethyl) phosphine hydrochloride and subsequent grafting of hydrophilic groups onto the reduced keratin by reaction with an acrylate sulfonate or acrylamide sulfonate through thiol-ene click chemistry. The modified substrates were characterized with Raman spectroscopy and scanning electron microscopy and evaluated for their performance changes in liquid moisture management, surface resistivity, and wet burst strength. The results have revealed that the thiol-acrylate reaction is more efficient than the thiol-acrylamide reaction, and the keratinous substrate modified with an acrylate sulfonate salt exhibits significantly improved antistatic and liquid moisture management properties.

Täna kell 18.30 avatakse Okupatsioonide muuseumis...

Index Scriptorium Estoniae

2004-01-01

Linnakultuuriaineline näitus "Paraad". Keskne idee on seotud rula kui eluhoiakuga. Osalevad Tuukka & Kätlin Kaila ning Vaughan Baker (London), Jani Tolin ja Freeman (Helsingi), Aadam Kaarma, Anu Samarüütel, Tarrvi Laamann, Marko Mäetamm & Kaido Ole, Lazer, Väike J, Veronika Valk, DJ Critical

Vabadus võtta vabalt / Maria-Kristiina Soomre

Index Scriptorium Estoniae

Soomre, Maria-Kristiina, 1978-

2004-01-01

Tänavakunstinäitus "Paraad" Eesti Lähimineviku Okupatsioonide Muuseumis. Osalevad Tuukka & Kätlin Kaila ning Vaughan Baker (London), Jani Tolin ja Freeman (Helsingi), Aadam Kaarma, Anu Samarüütel, Tarrvi Laamann, Marko Mäetamm & Kaido Ole, Lazer, Väike J, Veronika Valk, Kaarel Kulbin, DJ Critical

Estonia hukk jõuab kinolinale / Anari Koppel

Index Scriptorium Estoniae

Koppel, Anari

2003-01-01

Saksamaal esilinastub 2. oktoobril poliitiline põnevusfilm "Balti torm" ("Baltic Storm"), mis kujutab parvlaev "Estonia" hukku venelaste vandenõu tulemusena. Film jõuab Eestis linale novembri alul. Produtsendid on Jutta Rabe ja Kaj Holmberg, režissöör ja üks stsenariste Reuben Leder, peaosades Greta Scacchi ja Jürgen Prochnow. Kaasa teeb ka Donald Sutherland USA kindrali rollis. Eesti näitlejaist teevad kaasa Rein Oja ja väikeses rollis Urmas Alenderi lesk Helje Kaskel. Kõlab ka U. Alenderi laul

Nõukogude mood 1940. ja 50. aastatel / I. Andrejeva

Index Scriptorium Estoniae

Andrejeva, I.

1985-01-01

Sõjaaja riietusest, moejoonest. Moskva Moemajast (1949. aastast üleliiduline), moekunstnikke. Ajakirja "Zhurnal Mod" loomisest. 1940. aastate lõpuks kinnistunud moesuunast. Tegutsenud moemajad. Ajakirjas "Zhurnal Mod" (1954, nr. 2) väljakuulutatud kleidimudelite konkursi võitja - Melanie Kaarma, üks III preemia - Astrid Bulkina. S. Razumovskajalt artikkel "Eesti moekunstnikud" (Zhurnal Mod, 1954, nr. 3)

Pyriculins A and B, two monosubstituted hex-4-ene-2,3-diols and other phytotoxic metabolites produced by Pyricularia grisea isolated from buffelgrass (Cenchrus ciliaris).

Science.gov (United States)

Masi, Marco; Meyer, Susan; Górecki, Marcin; Mandoli, Alessandro; Di Bari, Lorenzo; Pescitelli, Gennaro; Cimmino, Alessio; Cristofaro, Massimo; Clement, Suzette; Evidente, Antonio

2017-11-01

Pyricularia grisea has been identified as a foliar pathogen on buffelgrass (Cenchrus ciliaris) in North America and was studied as a potential source of phytotoxins for buffelgrass control. Two monosubstituted hex-4-ene-2,3-diols, named pyriculins A and B, were isolated from its culture filtrate organic extract together with (10S,11S)-(-)-epipyriculol, trans-3,4-dihydro-3,4,8-trihydroxy-1(2H)-napthalenone, and (4S)-(+)-isosclerone. Pyriculins A and B were characterized by spectroscopic (essentially nuclear magnetic resonance [NMR], High-resolution electrospray ionization mass spectrometry [HRESIMS]) and chemical methods such as (4E)-1-(4-hydroxy-1,3-dihydroisobenzofuran-1-yl)hex-4-ene-2,3-diols. The relative and absolute configuration of these compounds was determined by a combination of spectroscopic (NMR, electronic circular dichroism [ECD]) and computational tools. When bioassayed in a buffelgrass coleoptile and radicle elongation test, (10S,11S)-(-)-epipyriculol proved to be the most toxic compound. Seed germination was much reduced and slowed with respect to the control and radicles failed to elongate. All five compounds delayed germination, but only (10S,11S)-(-)-epipyriculol was able to prevent radicle development of buffelgrass seedlings. It had no effect on coleoptile elongation, while the other four compounds caused significantly increased coleoptile development relative to the control. © 2017 Wiley Periodicals, Inc.

The IS-ENES climate4impact portal: bridging the CMIP5 and CORDEX data to impact users

Science.gov (United States)

Som de Cerff, Wim; Plieger, Maarten; Page, Christian; Tatarinova, Natalia; Hutjes, Ronald; de Jong, Fokke; Bärring, Lars; Sjökvist, Elin; Vega Saldarriaga, Manuel; Santiago Cofiño Gonzalez, Antonio

2015-04-01

The aim of climate4impact (climate4impact.eu) is to enhance the use of Climate Research Data and to enhance the interaction with climate effect/impact communities. The portal is based on 17 impact use cases from 5 different European countries, and is evaluated by a user panel consisting of use case owners. It has been developed within the IS-ENES European project and is currently operated and further developed in the IS ENES2 project. As the climate impact community is very broad, the focus is mainly on the scientific impact community. Climate4impact is connected to the Earth System Grid Federation (ESGF) nodes containing global climate model data (GCM data) from the fifth phase of the Coupled Model Intercomparison Project (CMIP5) and regional climate model data (RCM) data from the Coordinated Regional Climate Downscaling Experiment (CORDEX). This global network of climate model data centers offers services for data description, discovery and download. The climate4impact portal connects to these services using OpenID, and offers a user interface for searching, visualizing and downloading global climate model data and more. A challenging task is to describe the available model data and how it can be used. The portal informs users about possible caveats when using climate model data. All impact use cases are described in the documentation section, using highlighted keywords pointing to detailed information in the glossary. Climate4impact currently has two main objectives. The first one is to work on a web interface which automatically generates a graphical user interface on WPS endpoints. The WPS calculates climate indices and subset data using OpenClimateGIS/icclim on data stored in ESGF data nodes. Data is then transmitted from ESGF nodes over secured OpenDAP and becomes available in a new, per user, secured OpenDAP server. The results can then be visualized again using ADAGUC WMS. Dedicated wizards for processing of climate indices will be developed in close

Crystal structures of three anhydrous salts of the Lewis base 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU with the ring-substituted benzoic acid analogues 4-aminobenzoic acid, 3,5-dinitrobenzoic acid and 3,5-dinitrosalicylic acid

Directory of Open Access Journals (Sweden)

Graham Smith

2016-03-01

Full Text Available The anhydrous salts of the Lewis base 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU with 4-aminobenzoic acid [1-aza-8-azoniabicyclo[5.4.0]undec-7-ene 4-aminobenzoate, C9H17N2+·C7H6NO2− (I], 3,5-dinitrobenzoic acid [1-aza-8-azoniabicyclo[5.4.0]undec-7-ene 3,5-dinitrobenzoate, C9H17N2+·C7H3N2O6−, (II] and 3,5-dinitrosalicylic acid (DNSA [1-aza-8-azoniabicyclo[5.4.0]undec-7-ene 2-hydroxy-3,5-dinitrobenzoate, C9H17N2+·C7H3N2O7−, (III] have been determined and their hydrogen-bonded structures are described. In both (II and (III, the DBU cations have a common disorder in three of the C atoms of the six-membered ring moieties [site-occupancy factors (SOF = 0.735 (3/0.265 (3 and 0.686 (4/0.314 (4, respectively], while in (III, there is additional rotational disorder in the DNSA anion, giving two sites (SOF = 0.72/0.28, values fixed for the phenol group. In the crystals of (I and (III, the cation–anion pairs are linked through a primary N—H...Ocarboxyl hydrogen bond [2.665 (2 and 2.869 (3 Å, respectively]. In (II, the ion pairs are linked through an asymmetric three-centre R12(4, N—H...O,O′ chelate association. In (I, structure extension is through amine N—H...Ocarboxyl hydrogen bonds between the PABA anions, giving a three-dimensional structure. The crystal structures of (II and (III are very similar, the cation–anion pairs being associated only through weak C—H...O hydrogen bonds, giving in both overall two-dimensional layered structures lying parallel to (001. No π–π ring associations are present in any of the structures.

Enantioselective synthesis of possible diastereomers of heptadeca-1-ene-4,6-diyne-3,8,9,10-tetrol; putative structure of a conjugated diyne natural product isolated from Hydrocotyle leucocephala.

Science.gov (United States)

Prasad, Kavirayani R; Swain, Bandita

2011-04-01

Enantioselective synthesis of possible diastereomers of heptadeca-1-ene-4,6-diyne-3,8,9,10-tetrol, a structure proposed for the natural product isolated from Hydrocotyle leucocephala is accomplished. The reported spectral data of the natural product did not match those of any of the isomers that were synthesized and established that the structure proposed for the natural product is not correct and requires revision.

Eesti pensionisüsteem Euroopa Liidu ühiste pensionimärkide valguses / Lauri Leppik, Ene-Margit Tiit, Andres Võrk

Index Scriptorium Estoniae

Leppik, Lauri, 1964-

2004-01-01

Eesti pensionisüsteemi probleemid on senistest liikmesriikidest erinevad: pensionisüsteemi jätkusuutlikkus on hea ja pensionäride vaesusrisk ei ole kõrge, kuid asendusmäär on suhteliselt madal. See tähendab, et ei suudeta tagada EL-i pensionieesmärki, mis taotleb, et inimesel oleks pensionile jäädes võimalk säilitada oma varasem elatustase. Diagramm. Tabelid. Graafikud

Stereochemistry of 16a-Hydroxyfriedelin and 3-Oxo-16-methylfriedel-16-ene Established by 2D NMR Spectroscopy

Directory of Open Access Journals (Sweden)

Vagner Fernandes Knupp

2009-02-01

Full Text Available Friedelin (1, 3b-friedelinol (2, 28-hydroxyfriedelin (3, 16a-hydroxyfriedelin (4, 30-hydroxyfriedelin (5 and 16a,28-dihydroxyfriedelin (6 were isolated through fractionation of the hexane extract obtained from branches of Salacia elliptica. After a week in CDCl3 solution, 16a-hydroxyfriedelin (4 reacted turning into 3-oxo-16-methylfriedel-16-ene (7. This is the first report of a dehydration followed by a Nametkin rearrangement of a pentacyclic triterpene in CDCl3 solution occurring in the NMR tube. These seven pentacyclic triterpenes was identified through NMR spectroscopy and the stereochemistry of compound 4 and 7 was established by 2D NMR (NOESY spectroscopy and mass spectrometry (GC-MS. It is also the first time that all the 13C-NMR and 2D NMR spectral data are reported for compounds 4 and 7.

Cyclohex-1-ene carboxylic acids: synthesis and biological evaluation of novel inhibitors of human 5 alpha reductase.

Science.gov (United States)

Baston, Eckhard; Salem, Ola I A; Hartmann, Rolf W

2003-03-01

In search of novel nonsteroidal mimics of steroidal inhibitors of 5 alpha reductase, 4-(2-phenylethyl)cyclohex-1-ene carboxylic acids 1-5 were synthesized with different substituents in para position of the phenyl ring (1: N, N-diisopropylcarbamoyl, 2: phenyl, 3: phenoxy, 4: benzoyl, and 5: benzyl). The principal synthetic approach for the desired compounds consisted of a Wittig olefination between 1, 4-dioxaspiro [4.5]-decane-8-carbaldehyde (4g and the appropriate phosphonium salts. The compounds were tested for inhibition of human 5 alpha reductase isozymes 1 and 2 using DU 145 cells and preparations from prostatic tissue, respectively. They turned out to be good inhibitors of the prostatic isozyme 2 with compound 1 being the most potent one (IC(50) = 760 nM). Isozyme 1 was only slightly inhibited. It is concluded that the novel structures are appropriate for being further optimized, aiming at the development of a novel drug for the treatment of benign prostatic hyperplasia.

Haapsalu Piiskopilinnuse uuendamine / Lilian Hansar

Index Scriptorium Estoniae

Hansar, Lilian, 1949-

2015-01-01

Sihtasutus Haapsalu ja Läänemaa Muuseumid koostöös Eesti Arhitektide Liiduga korraldasid arhitektuurivõistluse, et valida välja parim arhitektuurne ja kasutusfunktsioonile sobiv lahendus Haapsalu piiskopilinnuse pealinnuse rekonstrueerimiseks kaasaegseks muuseumikompleksiks. Esimese koha sai töö märgusõnaga "Salaaed" (Margit Aule, Margit Argus, Siim Karro ja Mart Kadarik arhitektuuribüroost KAOS Arhitektid). Teise koha sai töö märgusõnaga "Helevalge" (Mari Hunt, Kalle Komissorov, Silver Liiberg, Kadri Klementi, Aet Ader ja Karin Tõugu arhitektuuribüroost b210). Kolmanda koha sai töö märgusõnaga "Ristvõlv" (Indrek Laos ja Andreas Kivi arhitektuuribüroost Flux projekt)

Superhydrophobic and Slippery Lubricant-Infused Flexible Transparent Nanocellulose Films by Photoinduced Thiol-Ene Functionalization.

Science.gov (United States)

Guo, Jiaqi; Fang, Wenwen; Welle, Alexander; Feng, Wenqian; Filpponen, Ilari; Rojas, Orlando J; Levkin, Pavel A

2016-12-14

Films comprising nanofibrillated cellulose (NFC) are suitable substrates for flexible devices in analytical, sensor, diagnostic, and display technologies. However, some major challenges in such developments include their high moisture sensitivity and the complexity of current methods available for functionalization and patterning. In this work, we present a facile process for tailoring the surface wettability and functionality of NFC films by a fast and versatile approach. First, the NFC films were coated with a layer of reactive nanoporous silicone nanofilament by polycondensation of trichlorovinylsilane (TCVS). The TCVS afforded reactive vinyl groups, thereby enabling simple UV-induced functionalization of NFC films with various thiol-containing molecules via the photo "click" thiol-ene reaction. Modification with perfluoroalkyl thiols resulted in robust superhydrophobic surfaces, which could then be further transformed into transparent slippery lubricant-infused NFC films that displayed repellency against both aqueous and organic liquids with surface tensions as low as 18 mN·m -1 . Finally, transparent and flexible NFC films incorporated hydrophilic micropatterns by modification with OH, NH 2 , or COOH surface groups, enabling space-resolved superhydrophobic-hydrophilic domains. Flexibility, transparency, patternability, and perfect superhydrophobicity of the produced nanocellulose substrates warrants their application in biosensing, display protection, and biomedical and diagnostics devices.

Ehtekunsti kõrgmäestik Münchenis / Kadri Mälk, Piret Hirv, Tanel Veenre

Index Scriptorium Estoniae

Mälk, Kadri, 1958-

2009-01-01

Ehtekunsti suurüritusest "Schmuckszene" ("Ehtepaik"). Arnoldsche Art Publishers esitles viit aasta paremaks ehtekunstiraamatuks tituleeritut, nende seas Eestis trükikojas Pakett trükitud raamatut "Just must" (kujundaja Aadam Kaarma, fotod: Tanel Veenre). Darling Publications'i poolt esitletud raamatust "The Compendium Finale of Contemporary Jewellery Makes", kus tutvustatakse kümmet eesti ehtekunstnikku, tekstide autorid on Kadri Mälk, Harry Liivrand ja Tamara Luuk

Inspection and monitoring plan, contaminated groundwater seeps 317/319/ENE Area, Argonne National Laboratory

International Nuclear Information System (INIS)

1996-01-01

During the course of completing the Resource Conservation and Recovery Act (RCRA) Facility Investigation (RFI) in the 317/319/East-Northeast (ENE) Area of Argonne National Laboratory-East (ANL-E), groundwater was discovered moving to the surface through a series of groundwater seeps. The seeps are located in a ravine approximately 600 ft south of the ANL-E fence line in Waterfall Glen Forest Preserve. Samples of the seep water were collected and analyzed for selected parameters. Two of the five seeps sampled were found to contain detectable levels of organic contaminants. Three chemical species were identified: chloroform (14--25 microg/L), carbon tetrachloride (56--340 microg/L), and tetrachloroethylene (3--6 microg/L). The other seeps did not contain detectable levels of volatile organics. The nature of the contaminants in the seeps will also be monitored on a regular basis. Samples of surface water flowing through the bottom of the ravine and groundwater emanating from the seeps will be collected and analyzed for chemical and radioactive constituents. The results of the routine sampling will be compared with the concentrations used in the risk assessment. If the concentrations exceed those used in the risk assessment, the risk calculations will be revised by using the higher numbers. This revised analysis will determine if additional actions are warranted

Cinamon kui uus nähtus kinomaastikul / Dagmar Reinolt

Index Scriptorium Estoniae

Reinolt, Dagmar

2009-01-01

Cinamoni kinoketi perspektiividest Eestis. Cinamoni nõukogu esimees Peeter Rebane, Tallinnfilmi juht Margit Vremmert ja kinoketi Forum Cinemas levijuht Lauri Kaare esitavad oma vaateid kinode ja filmilevi kohta Eestis

Krokodill sõi karu mett / Eero Kangor

Index Scriptorium Estoniae

Kangor, Eero, 1982-

2007-01-01

Tartu Ülikooli, Tartu Kõrgema Kunstikooli ja Tartu Kunstikooli õpilaste näitusest Tartu Kunstimuuseumis, kuraator Liisa Kaljula. Pikemalt Ronald Baumanni, Helen Kikkase, Margit Lõhmuse maalidest, Jana Huuli skulptuurist

Moeteater ühendab mitmest rahvusest Tallinna lapsi / Merike Teder

Index Scriptorium Estoniae

Teder, Merike

2005-01-01

Tallinnas Suur-Ameerika noortekeskuses avatud moeteatri Max Moda tegevusest. Rajaja ja tegevjuht Maksim Hlebnikov, kunstiline juht Margit Leerimaa. Moeteatri esimene etendus toimub 11. märtsil Rahvusraamatukogu suures konverentsisaalis

Teise korruse filmid Kanuti Gildi saalis : Zoova, Säde ja Piibemann

Index Scriptorium Estoniae

2008-01-01

Kanuti Gildi saali teisel korrusel filmiprogrammi "Teise korruse filmid" linastuvad täna Jasper Zoova filmid "Parallel Euro" ja "Armastuse barrikaadidel", Margit Säde "Failing Files", Taavi Piibemanni "Peategelased"

Estimación del impacto económico de los museos a través de las nuevas tecnologías de la información: el caso del museo Ene.Térmica

Directory of Open Access Journals (Sweden)

Vicente COLL-SERRANO

Full Text Available Cada vez es más necesario poner de relieve el potencial de la cultura como motor del desarrollo económico y su capacidad para generar ingresos y crear empleo. Por este motivo, en este trabajo se evalúa el impacto económico del museo Ene.Térmica sobre el territorio en el que se ubica, Ponferrada (Comunidad de Castilla y León, España. Para lograr este objetivo, la estimación de los distintos tipos de efectos necesarios para determinar el impacto de las actividades económicas vinculas a la existencia de Ene.Térmica se realiza, en base a la metodología de las Tablas Input-Output, mediante la herramienta Impactrimonio, una aplicación implementada sobre una plataforma web. Los resultados obtenidos indican que entre las actividades del museo y los flujos de demanda desplegados por el efecto arrastre de los visitantes se generó, entre los años 2011 y 2012, un incremento de la producción de más de 15 millones de euros, un incremento de las rentas de la población de casi 10 millones de euros y un aumento de la ocupación de 327 empleos.

Tallinna Teletorn = Tallinn's Television Tower / Andrus Kõresaar

Index Scriptorium Estoniae

Kõresaar, Andrus, 1975-

2013-01-01

Renoveeritud Teletornist. Ekspositsiooni autorid: Andrus Kõresaar, Liis Lindvere, Raili Paling, sisearhitektid: Liis Lindvere, Raili Paling, Margit Argus (KOKO Arhitektid). Arhitekti ja ESLi aastapreemiate žürii liikme Raivo Puusepa arvamus

Geeniandmepankade eetilised, juriidilised ja sotsiaalsed aspektid / Kristi Lõuk

Index Scriptorium Estoniae

Lõuk, Kristi

2004-01-01

Geeniandmepankadest ja ajakirja Trames erinumbrist "Human Genetic databases: ethical, legal and social issues" (vol. 8, no 1-2, 2004), mille külalistoimetajaks on TÜ eetikakeskuse juhataja prof Margit Sutrop

Linnalood / Andri Ksenofontov ; kommenteerinud R[eet] V[arblane

Index Scriptorium Estoniae

Ksenofontov, Andri, 1962-

2010-01-01

Erki Kasemetsa näitus "Kohad/Cities Revealed" ja Liina Siibi näitus "Gimme Danger" sarjast "Cityscape" Tallinna Linnagaleriis. Näitus "Jüri Kaarma lugemistuba" Vabaduse Galeriis. Rühmituse Johnson&Johnson näitus "Nothing Left to Save" Draakoni galeriis. Karel Koplimetsa, Sigrid Viiri ja Taaniel Raudsepa kunstiprojekt "OÜ Visible Solutions" Hobusepea galeriis. Inglise kunstniku Pamela June Crooki isikunäitus galeriis Vaal. Peeter Lauritsa fotonäitus "Trickster's Office" ArtDepoo galeriis

Kunstiakadeemia - 85 / Reet Varblane

Index Scriptorium Estoniae

Varblane, Reet, 1952-

1999-01-01

28. XI tähistas Eesti Kunstiakadeemia oma 85. aastapäeva. Kunstihariduse tulevikule pühendatud paneeldiskussioonist Sakala keskuse väikeses saalis, pressikonverentsist, pidulikust aktusest. Kunstiakadeemia esimesteks audoktoriteks promoveeriti Boris Bernshtein, Kaljo Põllu, Enno Hallek, Ilja Kabakov. Auliikmeteks nimetati Mari Adamson, Leo Gens, Leili Kuldkepp, Helene Kuma, Paul Luhtein, Arseni Mölder, Evald Okas, Helmut Oruvee, Bruno Tomberg, Jaan Vares. Juubelialbumi kujundas Jüri Kaarma, ajaloolise ülevaate kirjutas Leo Gens

Libavaida sugrusida uherles ja vurles kehus* / Maria Ulfsak-Šeripova

Index Scriptorium Estoniae

Ulfsak-Šeripova, Maria, 1981-

2010-01-01

Tim Burtoni filmist "Alice Imedemaal" (USA 2010), stsenarist Linda Woolverton, peaosades Mia Wasikowska, Johnny Depp. Lisaks kaks arvamust "3D poolt", autor Mann Jõgeda ja "3D vastu", autor Margit Tõnson

Elamuslik arhitektuur : Salto AB Sõmeru keskusehoone = Salto AB experiential architecture and the Sõmeru Community Centre / Carl-Dag Lige

Index Scriptorium Estoniae

Lige, Carl-Dag

2011-01-01

Arhitektuuribüroo Salto loomingust, mille fookus on kasutaja teenimisel ning meeleheal. 2010. a. valminud Sõmeru keskusehoonest. Arhitektid Maarja Kask, Ralf Lõoke, Karli Luik, kaasautorid Kristiina Arusoo, Margit Argus. Projekt: 2004

Villa Pirital : turvaliselt lõppenud arhitektuurieksperiment / Alvin Järving

Index Scriptorium Estoniae

Järving, Alvin, 1986-

2013-01-01

Masinlikuna detailitäpsest ja tehnoloogilisest eramust Pirital. Arhitekt Raul Vaiksoo (Raul Vaiksoo Arhitektuuribüroo). Sisearhitektid Raul Vaiksoo ja Margit Teikari (Stuudio TEMA). Ehitusaeg: 2011-2013. Elamispind: 374 m²

Tallinna Sakala keskuse projekt kütab kirgi / Aivo Vahemets

Index Scriptorium Estoniae

Vahemets, Aivo

2004-01-01

Raine Karbi projekteeritud hoone ümberehituse projekt telliti Inglismaalt büroost Burrow&Cave, OÜ Arhitektuuriagentuuri projektist loobuti. Eesti Arhitektide Liidu esinaise Margit Mutso ja arhitektuurinõukogu esimehe Peep Aaviksoo kommentaar

Theoretical study on the photolysis mechanism of 2,3-diazabicyclo[2.2.2]oct-2-ene.

Science.gov (United States)

Chen, Hui; Li, Shuhua

2005-09-28

A CASPT2/CASSCF study has been carried out to investigate the mechanism of the photolysis of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) under direct and triplet-sensitized irradiation. By exploring the detailed potential energy surfaces including intermediates, transition states, conical intersections, and singlet/triplet crossing points, for the first excited singlet (S(1)) and the low-lying triplet states (T(1), T(2), and T(3)), we provide satisfactory explanations of many experimental findings associated with the photophysical and photochemical processes of DBO. A key finding of this work is the existence of a significantly twisted S(1) minimum, which can satisfactorily explain the envelope of the broad emission band of DBO. It is demonstrated that the S(1) (n-pi*) intermediate can decay to the T(1) (n-pi*) state by undergoing intersystem crossing (rather inefficient) to the T(2) (pi-pi*) state followed by internal conversion to the T(1) state. The high fluorescence yield and the extraordinarily long lifetime of the singlet excited DBO are due to the presence of relatively high barriers, both for intersystem crossing and for C-N cleavage. The short lifetime of the triplet DBO is caused by fast radiationless decay to the ground state.

Kohtumine 8645 kolleegiga / Siiri Vallner, Indrek Peil

Index Scriptorium Estoniae

Vallner, Siiri, 1972-

2008-01-01

29. 06-3. 07 2008 Torinos toimunud Maailma Arhitektide Liidu (UIA) 23. kongressist teemal edastatav arhitektuur (Transmitting Architecture). Eesti osa balti ühisekspositsioonis koosnes Maja aastafilmide (autor Margit Mutso) näitamisest

Thiol-ene immobilisation of carbohydrates onto glass slides as a simple alternative to gold-thiol monolayers, amines or lipid binding.

Science.gov (United States)

Biggs, Caroline I; Edmondson, Steve; Gibson, Matthew I

2015-01-01

Carbohydrate arrays are a vital tool in studying infection, probing the mechanisms of bacterial, viral and toxin adhesion and the development of new treatments, by mimicking the structure of the glycocalyx. Current methods rely on the formation of monolayers of carbohydrates that have been chemically modified with a linker to enable interaction with a functionalised surface. This includes amines, biotin, lipids or thiols. Thiol-addition to gold to form self-assembled monolayers is perhaps the simplest method for immobilisation as thiolated glycans are readily accessible from reducing carbohydrates in a single step, but are limited to gold surfaces. Here we have developed a quick and versatile methodology which enables the use of thiolated carbohydrates to be immobilised as monolayers directly onto acrylate-functional glass slides via a 'thiol-ene'/Michael-type reaction. By combining the ease of thiol chemistry with glass slides, which are compatible with microarray scanners this offers a cost effective, but also useful method to assemble arrays.

Investigation of the fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) by certain substituted uracils

Energy Technology Data Exchange (ETDEWEB)

Anbazhagan, V. [School of Chemistry, Bharathidasan University, Tiruchirappalli 620024, Tamil Nadu (India); Renganathan, R. [School of Chemistry, Bharathidasan University, Tiruchirappalli 620024, Tamil Nadu (India)], E-mail: rrengas@yahoo.com

2009-04-15

The fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) by a series of uracils has been studied in water and acetonitrile solvents using steady-state and time-resolved fluorescence techniques. The steady-state fluorescence quenching technique has been performed in three different pHs (i.e. 4, 8 and 12). The bimolecular quenching rate constant (k{sub q}) increases with increase in pH of uracils. In acidic pH, a pure hydrogen atom abstraction is proposed as the quenching mechanism. This is supported by a pronounced solvent deuterium isotope effect. Electron transfer from the anionic form of uracil to the excited state of DBO is proposed as a mechanism for quenching in basic pH on the basis of highly exergonic thermodynamics obtained from the Rehm-Weller equation. The variation of k{sub q} is explained on the basis of the electronic effect of substitution in uracils as well.

Investigation of the fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) by certain substituted uracils

International Nuclear Information System (INIS)

Anbazhagan, V.; Renganathan, R.

2009-01-01

The fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) by a series of uracils has been studied in water and acetonitrile solvents using steady-state and time-resolved fluorescence techniques. The steady-state fluorescence quenching technique has been performed in three different pHs (i.e. 4, 8 and 12). The bimolecular quenching rate constant (k q ) increases with increase in pH of uracils. In acidic pH, a pure hydrogen atom abstraction is proposed as the quenching mechanism. This is supported by a pronounced solvent deuterium isotope effect. Electron transfer from the anionic form of uracil to the excited state of DBO is proposed as a mechanism for quenching in basic pH on the basis of highly exergonic thermodynamics obtained from the Rehm-Weller equation. The variation of k q is explained on the basis of the electronic effect of substitution in uracils as well

The photochemical reaction of 1,1-dicyano-3-phenylbut-1-ene. Simultaneous occurrence of p-methane and di-p-methane rearrangements

Directory of Open Access Journals (Sweden)

Silva Francisco A. da

1999-01-01

Full Text Available The direct photolysis of 1,1-dicyano-3-phenylbut-1-ene (3-MDCN was investigated at room temperature in solvents of different polarities (hexane, dichloromethane and acetonitrile. Cyclopropanes arising from both the di-pi-methane and pi-methane (1,2-H migration processes were obtained as photoproducts. The structures of the products were elucidated by ¹H-NMR, GC/MS, IR and chromatography. Relative quantum yield determination and GC analysis of sequential irradiations gave evidence that: i no secondary reactions occur, even at high conversions; ii the di-pi-methane rearrangement is significantly more affected by the solvent variation than the pi-methane reaction. Photosensitization with acetophenone or acetone did not yield any observable products. The existence of the simultaneous mechanisms and the observed effects were considered as evidence of a possible differentiation between localized and delocalized excitation on the excited state surface.

Tartu Keskkonnahariduse Keskuse Loodusmaja = Nature School of Tartu Environmental Education Centre

Index Scriptorium Estoniae

2015-01-01

Tartu Keskkonnahariduse Keskuse Loodusmaja Lille tänav 10, valminud 2013. Arhitektuurivõistlus 2010. Arhitektid Martin Kinks, Risto Parve, Kai Süda, Margit Valma (Karisma Arhitktid), Diana Taalfeld (NU Arhitektuur). Sisearhitekt Tõnis Kalve

Eesti oma kunstisuveniirid

Index Scriptorium Estoniae

2005-01-01

8. XII avati Tallinna Kunstihoone galeriis mitmikute näitus. Tallinna Kunstihoone, Bajozi veinikeldri ja AS Kiil & Co poolt 2005. a. sügisel väljakuulutatud mitmiku, käsitöönduslikult multiplitseeritava mahulise kunstiteose konkursi tulemused: I preemia (5000 kr.) - Merike Estna ja Maksim Shurini teos "Sound Picture", II (3000 kr.) - Andres Lõo "Jüri Arrak I" ja "J.A. I", III (2000 kr.) - Evelin Kuusiku "Pudel", eripreemia - Kärt Ojavee ja Aadam Kaarma "Albino"

Kirikusisustus / Krista Kodres

Index Scriptorium Estoniae

Kodres, Krista, 1957-

2005-01-01

Luteri kirikus Eestis 16.-18. sajandil. Kantsel, arhitektoonika ja teoloogiline sõnum. Eesti vanimad kantslid (Rannu, Jämaja). Tallinna Püha Vaimu kiriku kantsel. Evangelisti-ja apostliprogrammid. Pildiseeriatega programmid -Tallinna Niguliste kiriku kantsel (T. Heintze, 1624), Kaarma kiriku kantsel (J. Jakobson, 1645), Kolga-Jaani kiriku kantsel (u. 1680.-90. aastad). Teksti osa kantsli kujunduses. Töökojad ja stiilide muutumine. Ristimisnõu, triumfikrutsifiks, pihitool, pingid, väärid, orelirõdud, lühtrid. Bilbiograafia lk. 457-458

Olean-18-ene triterpenoids from Celastraceae species inhibit HIV replication targeting NF-kB and Sp1 dependent transcription.

Science.gov (United States)

Osorio, Alex A; Muñóz, Alejandro; Torres-Romero, David; Bedoya, Luis M; Perestelo, Nayra R; Jiménez, Ignacio A; Alcamí, José; Bazzocchi, Isabel L

2012-06-01

In the present study we report the isolation of nine new olean-18-ene triterpenes (1-9), along with three known ones (10-12), from Cassine xylocarpa and Maytenus jelskii. Their stereostructures have been elucidated on the basis of spectroscopic analysis, including 1D and 2D NMR techniques (COSY, ROESY, HSQC and HMBC), and spectrometric methods. The natural compounds and derivatives 13-15 have been tested for their potential as inhibitors of human immunodeficiency virus type 1 replication. Five compounds from this series displayed potent antiviral activity with IC(50)s in the micromolar range (1, 3, 4, 7 and 8) being 1 and 8 the most active compounds. The target of these compounds was different from antiretroviral drugs currently licensed as they act as inhibitors of enhancer-dependent transcription. The structure-activity relationships were established based on the regiosubstitution and oxidation degree of the triterpene scaffold, revealing that these aspects were able to modulate the selectivity and intensity of HIV inhibition. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

Allen Ginsberg kirjutab Ameerikast

Index Scriptorium Estoniae

2003-01-01

Arvustus: Ginsberg, Allen. Ameerika : valik luuletusi 1947-1996 / koostanud ja toimetanud Hasso Krull ; inglise keelest tõlkinud Contra, Lauri Kitsnik, Hasso Krull, Andres Langemets, Margit Langemets, Jürgen Rooste, Tõnu Õnnepalu. Tallinn : Perioodika, 2003

Informeeritud nõusolek ja muutuvad eetilised raamistikud bioeetikas / Kristi Lõuk

Index Scriptorium Estoniae

Lõuk, Kristi

2011-01-01

Ülevaade 4.-6. novembril 2010 toimunud informeeritud nõusoleku teemalisel konverentsil kõneldust. Esinejad: Tom L. Beauchamp, Margit Sutrop, Ruth Faden, Theda Rehbock, Kjetil Rommetveit, Toivo Maimets, Ruth Chadwick, Ants Nõmper, Jan Helge Solbakk

1,4a-Dimethyl-6-methyl-ene-5-(5,5,6,6-tetra-cyano-2-methyl-cyclo-hex-2-enylmeth-yl)deca-hydro-naphthalene-1-carboxylic acid: a trans-communic acid derivative.

Science.gov (United States)

Rejouani, Nezha; Auhmani, Aziz; Ait Itto, My Youssef; Benharref, Ahmed; Daran, Jean-Claude

2008-01-18

In the search for cancer chemopreventive agents, we have studied the Diels-Alder reaction of trans-communic acid with tetra-cyano-ethyl-ene in the presence of SiO(2) as catalyst. The title cycloadduct, C(26)H(30)N(4)O(2), was obtained in 75% yield. The mol-ecules are arranged in pairs through O-H⋯O hydrogen bonds, forming an R(2) (2)(8) ring motif. Both the fused cyclohexyl rings adopt a chair conformation, whereas the nonfused ring adopts a half-chair conformation.

Regularities of Transition : Top CEE Countries Compared / Helje Kaldaru

Index Scriptorium Estoniae

Kaldaru, Helje, 1950-

2000-01-01

Analüüsitakse Kesk- ja Ida-Euroopa riikide majandusnäitajate muutusi ja arenguid. Tabelid: SKP; majandusnäitajate kasv, arengutase, restruktureerimine ja ümberjaotus; üleminekunäitajad Baltimaades; prognooside ja tegelikkuse erinevus majandusnäitajates

Erivajadustega laste koolitee toob erilisi takistusi / Anu Mõistlik

Index Scriptorium Estoniae

Mõistlik, Anu

2003-01-01

Puudega laste vanemate probleemidest oma laste koolitamisel-kasvatamisel. Lisa: Arvamus [Tartu Descartes℗þi Lütseumi direktori Jaan Reinsoni ja Noorteklubi Händikäpp juhatuse esimehe Margit Rosentali seisukohad liikumispuudega laste kooli valiku võimalustest

Eesti laste suvi

Index Scriptorium Estoniae

2010-01-01

Laste suvisest koolivaheajast räägivad Eesti omavalitsuse ametnikud ja sotsiaaltöötajad: Kaasi Almers, Inna Kask, Aasa Saarna, Ülle Rajasalu, Merle Leopard, Aime Koger, Margit Pajo, Pilleriin Aalde, Andres Julle ja Tiiu Kuus

Uusi maalijaid Tartust

Index Scriptorium Estoniae

2007-01-01

Tartu Ülikooli maalikunsti eriala lõpetajate Veiko Klemmeri, Helen Kikkase ja Margit Lõhmuse tööde näitus Tartu Kunstimuuseumis ning Ronald Baumanni, Nadezhda Tshernobai ja Jäppe Johansoni näitus Tartu Kunstimajas

The synthesis of weak acidic type hybrid monolith via thiol-ene click chemistry and its application in hydrophilic interaction chromatography.

Science.gov (United States)

Zeng, Jiao; Liu, Shengquan; Wang, Menglin; Yao, Shouzhuo; Chen, Yingzhuang

2017-05-01

In this work, a porous structure and good permeability monolithic column was polymerized in UV transparent fused-silica capillaries via photo-initiated thiol-ene click polymerization of 2,4,6,8-tetravinyl-2,4,6,8-tetramethylcyclotetrasiloxane (TMTVS), pentaerythritol tetra(3-mercaptopropionate)(PETMP), itaconic acid, respectively, in the presence of porogenic solvents (tetrahydrofuranand methanol) and an initiator (2,2-dimethoxy-2-phenylacetophenone) (DMPA) within 30 min. The physical properties of this monolith were characterized by scanning electron microscopy (SEM), Fourier transform infrared (FT-IR) spectroscopy and nitrogen adsorption/desorption measurements. For an overall evaluation of the monolith in chromatographic application, separations of polycyclic aromatic hydrocarbons (PAHs), phenols, amides and bases were carried out. The column efficiency of this monolith could be as high as 112 560 N/m. It also possesses a potential application in fabrication of monoliths with high efficiency for c-LC. In addition, the resulting monolithic column demonstrated the potential use in analysis of environment waters. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Mustjõe asumi planeerimiskonkurss = The Competition for Planning the Mustjõe Community / Veljo Kaasik

Index Scriptorium Estoniae

Kaasik, Veljo

2002-01-01

Tallinna Mustjõe asumi korterelamu ja puhkeala ruumilise planeerimise võistluse eeltingimustest, premeeritud töödest. I preemia - Villem Tomiste, Mihkel Tüür, Ott Kadarik, II - Margit Mutso (koos kaastöölistega), III - Veronika Valk

Mis oli ja mida ei olnud : lisandusi kahele kirjutisele / Tiiu Erelt

Index Scriptorium Estoniae

Erelt, Tiiu, 1942-

2008-01-01

Lisandusi artiklitele: Koppel, Margit-Mariann. Mahalaskmine pärast surma //Eesti Ekspress, 23. aug. 2007, mis käsitleb Elmar Muugi saatust, ning: Raag, Raimo. Valter Tauli elust ja keelelisest tegevusest // Keel ja Kirjandus, (2007/Nov), nr. 11

LIFT 11 kutsub kogemist väärt kohtadesse / Silvia Pärmann

Index Scriptorium Estoniae

Pärmann, Silvia

2011-01-01

Installatsioonide festivalist LIFT 11 Tallinnas, kuraator Margit Aule. Margus Tamme ja Argo Peeveri installatsioonist "Face It", Raul Kalvo skulptuurist "Uurijad", Raul Kelleri installatsioonist "Tütarlaps kloaagis", Aet Aderi, Kaarel Künnapi, Grete Soosalu, Flo Kasearu, Andra Aaloe kunstiprojektist "O"

Hotell Arensburg : Lossi 15, Kuressaare / Liina Jänes

Index Scriptorium Estoniae

Jänes, Liina, 1977-

2008-01-01

Arensburg Boutique Hotel & Spa. Arhitektid: Margit Kärner, Raivo Kotov, Lea Laidra. Sisearhitektid: Liisi Murula, Raivo Kotov, Raili Paling. Peatöövõtja: EBC Ehitus AS. I korruse plaan, 2 värv. välisvaadet, 3 sisevaadet

Pärnu uue kunsti muuseumis on näitus "Kümme aastat moodsat kunsti Pärnus varakapitalistliku Eesti tingimustes"

Index Scriptorium Estoniae

2003-01-01

Osalevad Peeter Allik, Mila Balti, Chintis, Margit Joonas, Toomas Kuusing, Hannes Paldrok, Meeland Sepp, Inge Ting, Taje Tross, Andrus Joonas, Bille Tuul, Mariliis Beilmann, Olle Meyer, Sorge, rühmitus Non Grata, Asta Isak, Marianne Männi, Ville-Karel Viirelaid

Krister Kivi ümbermaailmareisi päevik / Krister Kivi

Index Scriptorium Estoniae

Kivi, Krister, 1975-

2006-01-01

Vestlus Londoni Eesti Seltsi juhatuse 95-aastase esimehe Tiit Reigoga. Autor kohtub ka Marokosse maja ostnud Margit Naptaliga, Tais baari pidava Tõnn Sarvega, Lõuna-Austraalias asuvas Thirlmere kommuunis elavate väliseestlastega ja Kanadas elava psühholoogi Endel Tulvinguga

Comment on "An unexpected formation of the novel 7-oxa-2-azabicyclo[2.2.1]hept-5-ene skeleton during the reaction of furfurylamine with maleimides and their bioprospection using a zebrafish embryo model" by C. E. Puerto Galvis and V. V. Kouznetsov, Org. Biomol. Chem., 2013, 11, 407.

Science.gov (United States)

Zubkov, F I; Kvyatkovskaya, E A; Nikitina, E V; Amoyaw, P N-A; Kouznetsov, V V; Lazarenko, V A; Khrustalev, V N

2017-08-02

It has been proved that the reaction between furfuryl amines and N-R-maleimides leads to the formation of aza-Michael addition products - 3-(furylmethylamino)-N-R-pyrrolidine-2,5-diones, instead of 7-oxa-2-azabicyclo[2.2.1]hept-5-enes, as this journal reported previously.

DVD. Margit Tõnson soovitab : "Libahundi needus" / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2006-01-01

ETV levitab DVD-l mängufilmi "Libahundi needus" : stsenaristid Margus Kasterpalu, Ilmar Raag ja Rainer Sarnet : režissöör Rainer Sarnet : osades Katariina Lauk, Rene Reinumägi : Shop of Dreams - Eesti Televisioon 2005

Pärnu mudaravila restaureerimine ja juurdeehitus = Restoration and extension of the Pärnu mud baths / Tarmo Teedumäe, Paco Ulman, Tüüne-Kristin Vaikla

Index Scriptorium Estoniae

Teedumäe, Tarmo, 1970-

2015-01-01

Restaureeritud ja uue juurdeehitusega Pärnu mudaravila Ranna puiestee 1, valminud 2014. Arhitektid Tarmo Teedumäe, Paco Ulman, Inga Raukas, Arhitektuuriagentuur, Allianss Arhitektid. Sisearhitektid Tüüne-Kristin Vaikla, Urmo Vaikla, Tuuli Trei, Margit Teikari (Vaikla Stuudio). 2014. aasta Kultuurkapitali Arhitektuuripreemia kandidaat

Eduka ettevõtte aluseks saab olla vaid looming / Ave Schmidt

Index Scriptorium Estoniae

Schmidt, Ave

2010-01-01

Tänapäeva ettevõttele tagavad konkurentsieelise inspiratsioon ja originaalsed ideed. Arvamust avaldavad Tallinna kohviku Nop asutaja Margit Aasmäe, Estonian Airi arendusdirektor Gunnar Mägi, Tallinna Kaubamaja müügi- ja turundusdirektor Enn Parel ja Balteco disainijuht Aivar Habakukk

Eesti interjöörileiud

Index Scriptorium Estoniae

2007-01-01

Tutvustatakse Ameerika moodi Mack-restorani Tartu maanteel - sisearhitekt Hillar Mänd koostöös restorani juhi Paul Lepikuga ja Arensburgi hotelli Kuressaares - arhitekt Margit Kärner koostöös Raivo Kotovi ja Lea Laidraga, sisearhitektid Liis Murula ja Raili Paling

"Klass : elu pärast" võitis peaauhinna

Index Scriptorium Estoniae

2009-01-01

Genfis toimunud rahvusvahelisel festivalil Cinema Tous Ecrans sai telesarjade võistlusprogrammis peaauhinna ETV sari "Klass : elu pärast", produtsent Gerda Kordemets, stsenarist Margit Keerdo, režissöörid Ilmar Raag, Gerda Kordemets, Liina Paakspuu, Priit Valkna ja Marek Miil

"Klass : elu pärast" võitis rahvusvahelisel festivalil peaauhinna

Index Scriptorium Estoniae

2009-01-01

Genfis toimunud rahvusvahelisel festivalil Cinema Tous Ecrans sai telesarjade võistlusprogrammis peaauhinna ETV sari "Klass : elu pärast", produtsent Gerda Kordemets, stsenarist Margit Keerdo, režissöörid Ilmar Raag, Gerda Kordemets, Liina Paakspuu, Priit Valkna ja Marek Miil

Kas Mustjõe kasvab linnaks? / Tõnu Laigu

Index Scriptorium Estoniae

Laigu, Tõnu

2002-01-01

Tallinna Mustjõe asumi korterelamu ja puhkeala ruumilise planeerimise ideevõistlusest. Preemiad: I - Ott Kadarik, Villem Tomiste, Mihkel Tüür (büroo Kosmos), II - Margit Mutso (büroo Eek & Mutso), III - Veronika Valk, ostupreemia - Sverre Laanjärv, Ivar Lubjak

Arutlus autorist ja ruumist / Meelis Oidsalu

Index Scriptorium Estoniae

Oidsalu, Meelis, 1978-

2010-01-01

Dokumentaalfilmi sarjas "Eesti lood" linastunud filmidest: "Beebilõust" - Saaremaa poeedist ja hiphop-muusikust Andrus Elbingust, režissöör ja stsenarist Margit Lillak ning "Pastacas" - Soomes elavast Eesti kunstnikust ja muusikust Ramo Tedrest, režissöör Rein Kotov

Poly(allyl methacrylate) functionalized hydroxyapatite nanocrystals via the combination of surface-initiated RAFT polymerization and thiol-ene protocol: a potential anticancer drug nanocarrier.

Science.gov (United States)

Bach, Long Giang; Islam, Md Rafiqul; Vo, Thanh-Sang; Kim, Se-Kwon; Lim, Kwon Taek

2013-03-15

Hydroxyapatite nanocrystals (HAP NCs) were encapsulated by poly(allyl methacrylate) (PolyAMA) employing controlled surface-initiated reversible addition-fragmentation chain transfer (SI-RAFT) polymerization of allyl methacrylate to afford HAP-PolyAMA nanohybrids. The subsequent thiol-ene coupling of nanohybrids with 2-mercaptosuccinic acid resulted HAP-Poly(AMA-COOH) possessing multicarboxyl group. The formation of the nanohybrids was confirmed by FT-IR and EDS analyses. The TGA and FE-SEM investigation were further suggested the grafting of PolyAMA onto HAP NCs. The utility of the HAP-PolyAMA nanohybrid as drug carrier was also explored. The pendant carboxyl groups on the external layers of nanohybrids were conjugated with anticancer drug cisplatin to afford HAP-Poly(AMA-COOH)/Pt complex. The formation of the complex was confirmed by FT-IR, XPS, and FE-SEM. In vitro evaluation of the synthesized complex as nanomedicine revealed its potential chemotherapeutic efficacy against cancer cell lines. Copyright © 2012 Elsevier Inc. All rights reserved.

Parimad Eesti modellid / Mari-Liis Helvik

Index Scriptorium Estoniae

Helvik, Mari-Liis

2008-01-01

Kersti Pedanik, Martin Merimaa agentuurist Living Models Agency; Olga Serova, Anett Griffel agentuurist EMA Model Management; Triin Villemsaar, Kertu-Maria Nurk agentuurist Beatrice MASS Modelnet; Karmen Pedaru, Carolina Bergstein agentuurist MJ-Models. Kommenteerivad Evelyn Mikomägi, Katrin Rannaväli, Beatrice, Margit Jõgger

Vabaduse väljaku ümberkujundamise ideekonkurss

Index Scriptorium Estoniae

1998-01-01

2. märtsil lõppenud Vabaduse väljaku ideekonkursil II preemia saanud Andres Alveri, Tiit Trummali ja Veljo Kaasiku tööst 'Pietro del Primo' ning III preemia saanud Margit Mutso, Madis Eegi ja Katrin Koovi tööst 'Varsti valge'.

Rene Valner ja Mikk Suursild - lihtsa elu tegelased / Susan Lahesalu

Index Scriptorium Estoniae

Lahesalu, Susan

2007-01-01

Arhitekt Rene Valner ja Mikk Suursild - tandem nimega UNITe - ehitavad ökonoomseid ja ökoloogilisi looduslikest materjalidest maju. Nende koostöös on valminud ka Peipsi ääres Nina külas 3 põhumaja. Ott Kadariku, Margit Mutso ja Kuido Kartau kommentaarid

Sherlock Holmes - esteedist härrasmees või kokaiinisõltlasest rusikakangelane? / Martin Saar

Index Scriptorium Estoniae

Saar, Martin

2010-01-01

Autor poleemiseerib Margit Adorfi kriitilise artikli "Härrast rusikakangelaseks" (Eesti Ekspress: TV Ekspress, 2010, 15.-21. jaan., lk. 3 ) teemadel. Võrdluses on Arthur Conan Doyle' poolt loodud tegelaskuju ja tema tõepärane kujutamine Guy Ritchie filmis "Sherlock Holmes" (Inglise-Austraalia-USA 2009)

Pärnus tähistatakse moodsa kunsti 10. aastapäeva

Index Scriptorium Estoniae

2003-01-01

Ülevaatenäitus Pärnu Uue Kunsti Muuseumis. Näitusel osalevad Peeter Mudist, Mila Balti, Chintis, Margit Joonas, Toomas Kuusing, Hannes Paldrok, Meeland Sepp, Inge Ting, Taje Tross, Andrus Joonas, Bille Tuul, Marliis Beilmann, Olle Meyes, Sorge, Non Grata, Asta Isak, Marianne Männi

Design and fabrication of uniquely shaped thiol-ene microfibers using a two-stage hydrodynamic focusing design.

Science.gov (United States)

Boyd, Darryl A; Shields, Adam R; Howell, Peter B; Ligler, Frances S

2013-08-07

Microfluidic systems have advantages that are just starting to be realized for materials fabrication. In addition to the more common use for fabrication of particles, hydrodynamic focusing has been used to fabricate continuous polymer fibers. We have previously described such a microfluidics system which has the ability to generate fibers with controlled cross-sectional shapes locked in place by in situ photopolymerization. The previous fiber fabrication studies produced relatively simple round or ribbon shapes, demonstrated the use of a variety of polymers, and described the interaction between sheath-core flow-rate ratios used to control the fiber diameter and the impact on possible shapes. These papers documented the fact that no matter what the intended shape, higher flow-rate ratios produced rounder fibers, even in the absence of interfacial tension between the core and sheath fluids. This work describes how to fabricate the next generation of fibers predesigned to have a much more complex geometry, as exemplified by the "double anchor" shape. Critical to production of the pre-specified fibers with complex features was independent control over both the shape and the size of the fabricated microfibers using a two-stage hydrodynamic focusing system. Design and optimization of the channels was performed using finite element simulations and confocal imaging to characterize each of the two stages theoretically and experimentally. The resulting device design was then used to generate thiol-ene fibers with a unique double anchor shape. Finally, proof-of-principle functional experiments demonstrated the ability of the fibers to transport fluids and to interlock laterally.

If It's Part Broke Half Fix It / Virginija Januskeviciute

Index Scriptorium Estoniae

Januskeviciute, Virginija, 1979-

2011-01-01

Kaasaegse Kunsti Eesti Keskuse ja Vilniuse Kaasaegse Kunsti Keskuse korraldatud näitus "If It's Part Broke, Half Fix It" Kaasaegse Kunsti Keskuses Vilniuses 28.01.-13.03.2011, kuraator Margit Säde Lehni. Osalesid kunstnikud Eestist, Leedust, Saksamaalt, Rootsist, Soomest, Inglismaalt ja Hollandist, osalejad loetletud

Janneli Kurvits, Eeva Masso : omanäoline apartmenthotell Marokos

Index Scriptorium Estoniae

2006-01-01

Janneli Kurvitsast (sünd. 1975) ja Eeva Massost (sünd. 1975), nende olulisemad teostatud objektid. J. Kurvitsa ja E. Masso kujundatud hotell (19. saj. lõpp, omanik Margit Naptal) Marokos Fezis. Sisearhitektide kommentaarid. Ill.: joonised, 19 värv. vaadet, värv. foto arhitektidest

Tartu ja Tallinna boheemkond ning lotovõitjad : Valitud palu dokumentaalfilmide sarjast "Eesti lood" / Olev Remsu

Index Scriptorium Estoniae

Remsu, Olev, 1947-

2009-01-01

ETVs näidatud dokumentaalfilmidest sarjas "Eesti lood" - Indrek Kangro film Jaan-Jürgen Klausist "Professionaalne amatöör" (eetris 3. XII 2008), Margit Lillaku film kunstnik Sandra Jõgevast "Ars longa" (eetris 29. X 2008), Eva-Katariina Taimre "Jackpot" lotovõitjatest (eetris 19. XI 2008)

Clinical efficacy of implementing Bio Immune(G)ene MEDicine in the treatment of chronic asthma with the objective of reducing or removing effectively corticosteroid therapy: A novel approach and promising results.

Science.gov (United States)

Glady, Gilbert

2018-06-01

Asthma is one of the diseases that demonstrates a wide range of variation in its clinical expression, in addition to an important heterogeneity in the pathophysiological mechanisms present in each case. The ever-increasing knowledge of the molecular signalling routes and the development of the Bio Immune(G)ene Medicine [BI(G)MED] therapy in line with this knowledge has revealed a whole novel potential set of self-regulation biological molecules, that may be used to promote the physiological immunogenic self-regulation mechanisms and re-establish the homeostatic balance at a genomic, proteomic and cellular level. The aim of the present study is to demonstrate that the sublingual use of a therapeutic protocol based on BI(G)MED regulatory BIMUREGs in the treatment of chronic asthma may reduce or suppress corticosteroid therapy and avoid its harmful side effects which some patients suffer when using this treatment on a long-term basis. The clinical efficacy of BI(G)MED for chronic asthma was evaluated through a multi-centre study carried out in 2016 implementing a 6-month BI(G)MED treatment protocol for Bronchial Asthma. A total of 61 patients from private medical centres and of European countries including Germany, Austria, France, Belgium and Spain participated. The manuscript describes in detail the clinical efficacy of Bio Immune(G)ene regulatory BI(G)MED treatment protocol that allows the reduction or total removal of the corticosteroid dose in patients with chronic asthma. No adverse reactions were observed. The BI(G)MED regulatory therapy brings novel therapeutic possibilities as an effective and safe treatment of chronic asthma. BI(G)MED was demonstrated to significantly reduce asthma severity when parameter compositions were all analysed by categorical outcomes. Therefore, it is considered a good therapeutic alternative for patients who respond poorly to steroids.

Reaction of singlet-excited 2,3-diazabicyclo[2.2.2]oct-2-ene and tert-butoxyl radicals with aryl-substituted benzofuranones.

Science.gov (United States)

Lundgren, Cecilia Vannesjö; Koner, Apurba L; Tinkl, Michael; Pischel, Uwe; Nau, Werner M

2006-03-03

5,7-Di-tert-butyl-3-aryl-3H-benzofuran-2-ones are lactones with potential antioxidant activity, owing to their abstractable benzylic C-H hydrogens. The fluorescence quenching of the azoalkane 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO), an established probe for the hydrogen-donor propensity of chain-breaking antioxidants, was investigated for 16 aryl-substituted benzofuranone derivatives [m,m-(CF3)2, p-CN, m-CN, p-CF3, p-COOCH3, m-CF3, p-Cl, p-F, H, m-CH3, p-CH3, m,p-(CH3)2, p-OCH3, o-CH3, o-CF3, o,m-(CH3)2]. Analysis of the rate data in terms of a linear free energy relationship yielded a reaction constant of rho = +0.35. This implies that n,pi*-excited DBO acts as nucleophilic species. In contrast, hydrogen abstraction of tert-butoxyl radicals from the benzofuranones was accelerated by electron-donating substituents (rho = -0.23), in conformity with the electrophilic character of oxygen-centered alkoxyl radicals. Possible implications for the optimization of the hydrogen-donor propensity of antioxidants through structural variation are discussed.

Eesti rootslased Göteborgi raamatumessil "Bok & Bibliotek" / Aino Siebert, Georg von Stackelberg

Index Scriptorium Estoniae

Siebert, Aino

2007-01-01

rets. rmt.: "Runö" historien om svenskön i Rigabukten" / koostaja Jörgen Hedman. "Estlandsvenskarna som kom till Roslagen" / koostaja Kristina Rosen. "Berättelser från Nargö" - "Naisaare Lood" / koostaja Margit Rosen Norlin. "Kärslätt min by" / koostaja Sven Svärd

Investigations on the fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene by certain flavonoids.

Science.gov (United States)

Anbazhagan, V; Kalaiselvan, A; Jaccob, M; Venuvanalingam, P; Renganathan, R

2008-05-29

The fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) by seven flavonoids namely flavone, flavanone, quercetin, rutin, genistein, diadzein and chrysin has been investigated in acetonitrile and dichloromethane solvents. The bimolecular quenching rate constants lie in the range of 0.09-5.75 x 10(9)M(-1)s(-1) and are explained in terms of structure of the flavonoids studied. The reactivity of flavonoids are in the order: quercetin>rutin>genistein>diadzein>chrysin>flavone>flavanone. The quenching rate constants (k(q)) increase with increase in the number of -OH groups. The endergonic thermodynamic values of DeltaG(et) reveal that electron transfer quenching mechanism can be ruled out. Bond dissociation enthalpy calculations reveal that the position of -OH is important. Further in vitro-antioxidant activities of flavonoids were evaluated with rat liver catalase by gel electrophoresis. The deuterium isotope effect thus observed in this work provides evidence for hydrogen abstraction involved in the quenching process of singlet excited DBO by flavonoids. The data suggest the involvement of direct hydrogen atom transfer (radical scavenging) in the fluorescence quenching of DBO. Bond dissociation enthalpy calculation performed at B3LYP/6-31G(p')//B3LYP/3-21G level are in excellent agreement with the above observations and further reveal that the number OH groups and position of them decide the quenching ability of the flavonoids.

Milline on ilus maja? / Sulev Oll

Index Scriptorium Estoniae

Oll, Sulev, 1964-

2008-01-01

Ilusatest majadest ja arhitektuurikonkursside võiduprojektidest. Konkursist "Brick Award". Tallinna sünagoog valiti rahvusvahelise tellisarhitektuuri aastaraamatusse "brick'08" (arhitektid Lembit-Kaur Stöör, Andrus Kõresaar, Tõnis Kimmel arhitektuuribüroost KOKO Arhitektid). Loetletud konkursi "Aasta betoonehitis" võitjad läbi aegade. Kommenteerivad Margit Mutso, Emil Urbel

Uus Tartu Loodusmaja = The new Tartu Nature Building / Tiit Sild

Index Scriptorium Estoniae

Sild, Tiit, 1977-

2010-01-01

Tartu Loodusmaja avalikust arhitektuurivõistlusest, kvalifitseerimistingimustest, energiatõhususest ja žürii tööst. 1. preemia sai töö "Känd", autorid Diana Taalfeld, Kai Süda, Margit Valma, Martin Kinks (Urmas Lõokese AB / Karisma Arhitektid). Nimetatud 2. ja 3. koha saanud tööd, autorid

Thiol-ene and photo-cleavage chemistry for controlled presentation of biomolecules in hydrogels.

Science.gov (United States)

Grim, Joseph C; Marozas, Ian A; Anseth, Kristi S

2015-12-10

photochemical methods have led to important advances in the tissue regeneration community, namely the thiol-ene photo-click reaction for bioconjugation and photocleavage reactions that allow for the removal of protecting groups. Specific examples will be highlighted where these methodologies have been used to engineer hydrogels that control and direct cell function with the aim of inspiring their use in regenerative medicine. Copyright © 2015 Elsevier B.V. All rights reserved.

Festival "Lift 11" toob pealinna pööraseid installatsioone / Kristjan Pihl

Index Scriptorium Estoniae

Pihl, Kristjan

2011-01-01

Linnainstallatsioonide festivali "LIFT11" algselt väljakuulutatud 17 võidutööst teostub 11. 17. augustil avatakse Lasnamäe kanali ääres skulptuur "Uurijad", 23. augustil Russalka juures Margus Tamme ja Argo Peeveri installatsioon "Face it". Ärajäävatest töödest. Tutvustab kuraator Margit Aule

Properties of solid electrolyte interphase formed by prop-1-ene-1,3-sultone on graphite anode of Li-ion batteries

International Nuclear Information System (INIS)

Li, Bin; Xu, Mengqing; Li, Benzhen; Liu, Yanlin; Yang, Liang; Li, Weishan; Hu, Shejun

2013-01-01

Highlights: • SEI formed by PES on NG was characterized with charge/discharge test, SEM, FTIR, and XPS. • NG in PC-based electrolyte can be well protected using PES. • Sulfur-containing species is the main component of the SEI formed by PES. • Preferable reduction of PES results in the formation of protective SEI on NG. -- Abstract: The physical and chemical properties of the solid electrolyte interphase (SEI) formed by prop-1-ene-1,3-sultone (PES) on graphite anode in propylene carbonate (PC) based electrolyte for lithium ion battery were investigated by charge–discharge test, scanning electron spectroscopy with energy dispersive X-ray spectroscopy (SEM–EDS), Fourier transform infrared spectroscopy (FTIR), and X-ray photoelectron spectroscopy (XPS). It is found that the charge–discharge performance of the cell LiCoO 2 /natural graphite (NG) using PC-based electrolyte containing 3 wt% PES is superior to that containing 6 wt% propane sultone (PS), an SEI formation additive that has the similar molecular structure to PES but is reduced not as easily as PES. The results from SEM–EDS, FTIR and XPS show that the structure of graphite has been protected and some S-containing species are proven to be components of the SEI, suggesting that the preferable reduction of PES plays an important role in the formation of a protective SEI on NG

Coplas de la tierra en la chilena, lírica tradicional de la Mixteca

Directory of Open Access Journals (Sweden)

Grissel Gómez Estrada

2015-04-01

Full Text Available ABSTRACT: This paper seeks to highlight the traditional lyrical genre known as Chilean, who will sing and dance mostly in the Mexican’s Mixteca region. I will focus on the analysis of the ‘verses of the Earth’, as he calls them Margit Frenk, as I feel that these characterize the genre, based on a corpus of more than a hundred chilean. In addition, these verses will give an account of the culture of the inhabitants of the region. RESUMEN: El presente trabajo pretende dar a conocer el género lírico tradicional conocido como chilena, que se canta y baila sobre todo en la región mexicana de la Mixteca. Me centraré en el análisis de las ‘coplas de la tierra’, como las llama Margit Frenk, pues considero que éstas caracterizan al género, a partir de un corpus de más de cien chilenas. Asimismo, dichas coplas van a dar cuenta de la cultura de los habitantes de la región.

Sotsiaalne kapital ja jätkusuutlik majandusareng / Helje Kaldaru, Katrin Tamm

Index Scriptorium Estoniae

Kaldaru, Helje, 1950-

2003-01-01

Ülevaade sotsiaalse kapitali mõistest ja peamistest suundumustest selle käsitlemisel, sotsiaalse kapitali mõõtmise võimalustest. Sotsiaalse kapitali analüüs Eestis võrrelduna Euroopa Liidu liikmesmaade, teiste kanditaat- ja siirderiikidega, sotsiaalse kapitali kujunemine maakondade lõikes. Tabelid

IN0523 (Urs-12-ene-3α,24β-diol) a plant based derivative of boswellic acid protect Cisplatin induced urogenital toxicity.

Science.gov (United States)

Singh, Amarinder; Arvinda, S; Singh, Surjeet; Suri, Jyotsna; Koul, Surinder; Mondhe, Dilip M; Singh, Gurdarshan; Vishwakarma, Ram

2017-03-01

The limiting factor for the use of Cisplatin in the treatment of different type of cancers is its toxicity and more specifically urogenital toxicity. Oxidative stress is a well-known phenomenon associated with Cisplatin toxicity. However, in Cisplatin treated group, abnormal animal behavior, decreased body weight, cellular and sub-cellular changes in the kidney and sperm abnormality were observed. Our investigation revealed that Cisplatin when administered in combination with a natural product derivative (Urs-12-ene-3α,24β-diol, labeled as IN0523) resulted in significant restoration of body weight and protection against the pathological alteration caused by Cisplatin to kidney and testis. Sperm count and motility were significantly restored near to normal. Cisplatin caused depletion of defense system i.e. glutathione peroxidase, catalase and superoxide dismutase, which were restored close to normal by treatment of IN0523. Reduction in excessive lipid peroxidation induced by Cisplatin was also found by treatment with IN0523. The result suggests that IN0523 is a potential candidate for ameliorating Cisplatin induced toxicity in the kidney and testes at a dose of 100mg/kg p.o. via inhibiting the oxidative stress/redox status imbalance and may be improving the efflux mechanism. Copyright © 2017 Elsevier Inc. All rights reserved.

Eesti Maanteemuuseumi välialad : avalik maastikuarhitektuuri ideekonkurss = Public Landscape Architectural Idea Competition "Outdoor Spaces of the Estonian Highway Museum" / Toomas Muru

Index Scriptorium Estoniae

Muru, Toomas, 1970-

2004-01-01

Põlvamaal, endises Varbuse hobupostijaamas avatava Eesti Maanteemuuseumi välialade konkursi eesmärgist, tingimustest, žürii koosseisust, premeeritud töödest. Preemiad: I - Margit Kärner, II - Karli Luik, Ralf Lõoke ja Maarja Kask, III - Taavi Kuningas, Andrus Padu ja Martin Prommik, ergutuspreemiad - Piret Looveer ja Remi Kübar ning Maria Pukk ja Ivar Lubjak

"Kunstisuvi" Pärnus / Sirje Eelma

Index Scriptorium Estoniae

Eelma, Sirje, 1950-

2002-01-01

VIII "Kunstisuve" väikeformaadilise maali näitus "Minima(a)l - tsiteeri(ta)v maalikunst" Pärnu Linnagaleriis. Kuraator Kreg A-Kristring, 36 osalejat. Galerii fassaadil Margit Joonase ülisuur maal. Endla Teatrigaleriis eesti noortekunsti näitus "Autoportree". Kuraator Margaret Tali. Osalejad loetletud. Avamisel Krõõt Juuraku ja Merle Saarva häppening "Green house"

Mis tähendus on sündmusel "Kunstisuvi" teile, korraldajatele? / Sirje Eelma

Index Scriptorium Estoniae

Eelma, Sirje, 1950-

2002-01-01

"Kunstisuve 2002" näitused: Pärnu Linnagaleriis Kreg A-Kristringi kureeritav "Tsiteeri(ta)v maalikunst", Margit Joonase maal galerii välisseinal, Terje Ojaveri installatsioon, Endla Teatrigaleriis Margaret Tali kureeritav noortenäitus, Vallikäärus Rait Pärja korraldatav skulptuuri-workshop, Roma Kungsgardis Gotlandi saarel eesti-rootsi kunsti ühisnäitus (nimetatud osalejad Eestist)

Kuldala elamurajoon Rae vallas Harjumaal / Lembit-Kaur Stöör, Margus Maiste, Raivo Kotov...[jt.

Index Scriptorium Estoniae

2008-01-01

joonised: vaade, I-IV korruse plaan (2), planeeringu makett, 5 värv. fotot: 3 välis- ja 2 sisevaadet; fotod: Kaido Haagen; arhitektuurne projekt: KOKO Arhitektid.; autorid: L.-K. Stöör, M. Maiste, R. Kotov, T. Kimmel, hoonete projekteerimine: L.-K. Stöör, M. Maiste, Olga Batuhtina, maastikuarhitektuur: Margit Kärner

Kuressaare kursiivis on Arensburg / Urmas Oja

Index Scriptorium Estoniae

Oja, Urmas, 1981-2012

2007-01-01

Arensburg Boutique Hotel & Spa lisahoone Kuressaares Lossi t. 15. Arhitektid: Raivo Kotov, Margit Kärner ja Lea Laidra, KOKO Arhitektid OÜ. Sisekujundus: Liisi Murula Maridisain OÜ-st ja Raili Paling KOKO Arhitektid OÜ-st. Ehitustööde peatöövõtja: AS EBC Ehitus. Ehitusaeg: 2005-2007. 7 värv. välisvaadet

Noorte eesti režissööride uued filmid Sõpruses / Mari Peegel

Index Scriptorium Estoniae

Peegel, Mari, 1978-

2005-01-01

Sõpruse kinos esilinastub homme kaks eesti lühimängufilmi - "Vanameeste paradiis" : stsenaristid Ove Musting, Urmas Lennuk : režissöör Ove Musting : mängivad Tõnu Aav, Aleksander Eelmaa jt ning "Ukse taga" : stsenarist Margit Keerdo : režissöör Andrus Tuisk : osades Hele Kõre, Karin Lätsim, Kirill Käro, Igor Gavrilov

Esilinastuseni jõuab kaks uut Eesti lühimängufilmi

Index Scriptorium Estoniae

2005-01-01

Sõpruse kinos esilinastub homme kaks eesti lühimängufilmi - "Vanameeste paradiis" : stsenaristid Ove Musting, Urmas Lennuk : režissöör Ove Musting : mängivad Tõnu Aav, Aleksander Eelmaa jt ning "Ukse taga" : stsenarist Margit Keerdo : režissöör Andrus Tuisk : osades Hele Kõre, Karin Lätsim, Kirill Käro, Igor Gavrilov

Ära tee, tee! = Do not do it, do it! / Rebeka Põldsam

Index Scriptorium Estoniae

Põldsam, Rebeka, 1989-

2016-01-01

Margit Säde-Lehni kuraatorinäitus "DOings & kNOTs. Kunst ja/või instruktsioon" Tallinna Kunstihoones. Lähtepunktiks on Hans Ulrich Obristi 1993. a. algatatud projekt „Do it”. Kunstihoonesse on kutsutud 20 kunstnikku/rühmitust üle Euroopa, et tõlgendada kellegi teise jäetud instruktsioone ja teha nende järgi uusi teoseid

Regulation of a putative corticosteroid, 17, 21-dihydroxypregn-4-ene, 3, 20-one, in sea lamprey, Petromyzon marinus.

Science.gov (United States)

Roberts, Brent W.; Didier, Wes; Satbir, Rai; Johnson, Nicholas S.; Libants, Scot V.; Sang-Seon, Yun; Close, David

2013-01-01

In higher vertebrates, in response to stress, the hypothalamus produces corticotropin-releasing hormone (CRH), which stimulates cells in the anterior pituitary to produce adrenocorticotropic hormone (ACTH), which in turn stimulates production of either cortisol (F) or corticosterone (B) by the adrenal tissues. In lampreys, however, neither of these steroids is present. Instead, it has been proposed that the stress steroid is actually 17,21-dihydroxypregn-4-ene-3,20-dione (11-deoxycortisol; S). However, there have been no studies yet to determine its mechanism of regulation or site of production. Here we demonstrate that (1) intraperitoneal injections of lamprey-CRH increase plasma S in a dose dependent manner, (2) intraperitoneal injections of four lamprey-specific ACTH peptides at 100 lg/kg, did not induce changes in plasma S concentrations in either males or females; (3) two lamprey-specific gonadotropin-releasing hormones (GnRH I and III) and arginine-vasotocin (AVT), all at single doses, stimulated S production as well as, or to an even greater extent than CRH; (4) sea lamprey mesonephric kidneys, in vitro, converted tritiated 17a-hydroxyprogesterone (17a-P) into a steroid that had the same chromatographic properties (on HPLC and TLC) as S; (5) kidney tissues released significantly more immunoassayable S into the incubation medium than gill, liver or gonad tissues. One interpretation of these results is that the corticosteroid production of the sea lamprey, one of the oldest extant vertebrates, is regulated through multiple pathways rather than the classical HPI-axis. However, the responsiveness of this steroid to the GnRH peptides means that a reproductive rather than a stress role for this steroid cannot yet be ruled out.

Plaadid / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2005-01-01

Uute heliplaatide Gorillaz "Demon Days", Nine Inch Nails "With Teeth", Weezer "Make Believe", CDOASS "Extra Fingers", System Of A Down "Mezmerize", Crosby Stills & Nash "Createst Hits 2005", "The Others"

Plaadid / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2005-01-01

Uutest heliplaatidest Saint Etienne "Tales From Turnpike House", "Team Sleep", Jamiroquai "Dynamite", Life Of Agony "Broken Valley", The Wallflowers "Rebel, Sweetheart", morcheeba "The Antidote", Amerie "Touch"

Plaadid / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2005-01-01

Uutest heliplaatidest Metro Luminal "Reboot", Rannap, Rein "Tantsib klaveril", Hüpnosaurus "Lint nr 33", Eminem "Encore", Marianne Faithfull "Before the Poision", Aerosmith "You Gotta move", Evanescence "Anywhwre but Home"

Pop / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2006-01-01

Heliplaatidest: Massive Attack "Collected: the Best of Massive Attack", Daft Punk "Musique Vol.1 - 1993-2005", Psychoterror "Anarhia ja dekadents", The Bluetones "A Rough Outline: The Singles & B-Sides 95-03", Pretty Girls Make Graves "⁹lan Vital", DFA "The DFA Remixes: Chapter One"

Plaadid / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2004-01-01

Uutest heliplaatidest Travis "Singles", Talking Heads "The Best Of", The Hidden Cameras "Mississauga Goddam", Aberfeldy "Young Forever", The Music "Welcome To The North", Bitch Alert "Kill Your Darlings", Manic Street Preachers "Lifeblood", Depeche Mode "Remixes81-04"

Plaadid / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2004-01-01

Uutest heliplaatidest Embrace "Out of Nothing", Arrested Development "Among The Trees", Kalm, Kristjan "Generalissimus", Bossacucanova "Uma batida diferente", Adams, Bryan "Room Service", "Kasabian", Korn "Greatest Hits. Vol 1", Papa Roach "Getting Away With Murder"

Plaadid / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2004-01-01

Uutest heliplaatidest "Maria Rita", "Between Heaven and Earth", Marilyn Manson "Lest We Forget. The Best Of", Phil Collins "Love Songs", Dizzee Rascal "Showtime", Bruce Hornsby "Halcyon Days", Bill Frisell "Unspeakable"

Ühendatud inimeste üksindus / Martin Ehala

Index Scriptorium Estoniae

Ehala, Martin, 1963-

2007-01-01

Vastukaja art.: Sutrop, Margit. Vabadus ja vastutus // Postimees : AK : Arvamus. Kultuur (2007) 20. jaan. Artikli autor Martin Ehala selgitab, miks laguneb lääne ühiskondades sotsiaalne kapital ja kaob ühiskonda liitev meie-tunne. Kolmest olulisest sotsiaalsest nähtusest : individualismist, kollektivismist ja sotsiaalsest kapitalist. Üks olulisemaid tingimusi meie-tunde arenemiseks on ühiste väärtuste olemasolu

Kodu osa isiklikus ja ühiskondlikus elus

Index Scriptorium Estoniae

2008-01-01

15. II avatakse Eesti Tarbekunsti-ja Disainimuuseumis Eesti Vabariigi 90. aastapäevale pühendatud näitus "Varamu. Esindusruum ja moodne kodu 1918-1940", mille on koostanud Merike Alber, kujundanud Margit Lillak ning graafiliselt kujundanud Denes Farkas. Eksponaadid on pärit riigikogust, presidendi kantseleist, Eesti muuseumidest ning erakogudest. Lõik Hanno Kompuse artiklist ajakirjas "Kaunis Kodu", 1935, nr. 3

Kodu osa isiklikus ja ühiskondlikus elus

Index Scriptorium Estoniae

2008-01-01

15. veebruaril 2008. a. avatakse Eesti Tarbekunsti-ja Disainimuuseumis Eesti Vabariigi 90. aastapäevale pühendatud näitus "Varamu. Esindusruum ja moodne kodu 1918-1940", mille on koostanud Merike Alber, kujundanud Margit Lillak ning graafiliselt kujundanud Denes Farkas. Eksponaadid on pärit riigikogust, presidendi kantseleist, Eesti muuseumidest ning erakogudest. Lõik Hanno Kompuse artiklist ajakirjas "Kaunis Kodu", 1935, nr. 3

Tervisliku liikumise tähendusest - on see sport või midagi muud? / Marko Uibu

Index Scriptorium Estoniae

Uibu, Marko, 1983-

2016-01-01

Terviseedenduse jaoks kommunikatiivsetest, liikumise tähendustega seotud väljakutsetest. Liikumise spordikesksest käsitlusest. Tartu Ülikooli veetavast liikumisprojektist, mis püüab kaasa aidata laste aktiivsemale liikumisele nii vahetundides kui ka ainetundides. Artikkel põhineb projekti "Laste ja noorte tõenduspõhise liikumisprogrammi arendamine" käigus Margit Kelleri, Marko Uibu ja Triin Vihalemma koostatud uuringuraportil

Elamu Kalamaja piiril : Noole 4, Tallinn = Residential Building on the Edge of the Kalamaja District : Noole 4, Tallinn / Triin Ojari

Index Scriptorium Estoniae

Ojari, Triin, 1974-

2008-01-01

42 korteriga elamu, mille alumine korrus on endise tööstushoone paemüür, II korrus on puidust, III korrus on kaetud Cortenterasega. Projekteerija: Arhitektuuribüroo Eek & Mutso. Autorid: Margit Mutso, Kristi Põldme. Konstruktor: OÜ Kuup Ehitus. Ehitaja: YIT. Projekt: 2006, valmis: 2007. M. Mutso hoone kavandamisest ja valmimisest. I-IV korruse plaan, 6 värv. välisvaadet

Kuni 13. III saab Y-galeriis vaadata EKA avatud akadeemia näitust "Lavastused ja interpretatsioonid"

Index Scriptorium Estoniae

2005-01-01

Stseenid modellidega on lavastanud Tiina Tammetalu, maalinud-interpreteerinud üliõpilased Ulvi Kuldkepp, Margit Maksing, Liis-Theresia Ulman, (Margus) Soho Fond, Ian Oja, Alissa Didõk-Riikjärv ja Monika Sorokina. Väljapaneku on kujundanud T. Tammetalu ja U. Kuldkepp. Projekt "Happy" on T. Tammetalu kureeritav näitusesari, mis tutvustab tema juhendamisel tehtud üliõpilaste töid

Ring opening of 2-aza-3-borabicyclo[2.2.0]hex-5-ene, the Dewar form of 1,2-dihydro-1,2-azaborine: stepwise versus concerted mechanisms

Directory of Open Access Journals (Sweden)

Holger F. Bettinger

2013-04-01

Full Text Available The ring opening of the Dewar form of 1,2-dihydro-1,2-azaborine, 2-aza-3-borabicyclo[2.2.0]hex-5-ene (3 is investigated by theoretical methods by using multiconfiguration SCF (CASSCF and coupled cluster theory [CCSD(T] with basis sets up to polarised quadruple-zeta quality. The title compound was previously reported to form photochemically in cryogenic noble gas matrices from 1,2-dihydro-1,2-azaborine (4. Four reaction paths for the thermal ring opening of 3 to 4 could be identified. These are the conventional disrotatory and conrotatory electrocyclic ring-opening pathways where the BN unit is only a bystander. Two more favourable paths are stepwise and involve 1,3-boron–carbon interactions. The lowest energy barrier for the isomerisation reaction, 22 kcal mol−1, should be high enough for an experimental observation in solution. However, in solution the dimerisation of 3 is computed to have a very low barrier (3 kcal mol−1, and thus 3 is expected to be a short-lived reactive intermediate.

IN0523 (Urs-12-ene-3α,24β-diol) a plant based derivative of boswellic acid protect Cisplatin induced urogenital toxicity

International Nuclear Information System (INIS)

Singh, Amarinder; Arvinda, S; Singh, Surjeet; Suri, Jyotsna; Koul, Surinder; Mondhe, Dilip M.; Singh, Gurdarshan; Vishwakarma, Ram

2017-01-01

The limiting factor for the use of Cisplatin in the treatment of different type of cancers is its toxicity and more specifically urogenital toxicity. Oxidative stress is a well-known phenomenon associated with Cisplatin toxicity. However, in Cisplatin treated group, abnormal animal behavior, decreased body weight, cellular and sub-cellular changes in the kidney and sperm abnormality were observed. Our investigation revealed that Cisplatin when administered in combination with a natural product derivative (Urs-12-ene-3α,24β-diol, labeled as IN0523) resulted in significant restoration of body weight and protection against the pathological alteration caused by Cisplatin to kidney and testis. Sperm count and motility were significantly restored near to normal. Cisplatin caused depletion of defense system i.e. glutathione peroxidase, catalase and superoxide dismutase, which were restored close to normal by treatment of IN0523. Reduction in excessive lipid peroxidation induced by Cisplatin was also found by treatment with IN0523. The result suggests that IN0523 is a potential candidate for ameliorating Cisplatin induced toxicity in the kidney and testes at a dose of 100 mg/kg p.o. via inhibiting the oxidative stress/redox status imbalance and may be improving the efflux mechanism. - Highlights: • Synthesis of a novel boswellic acid derivative (IN0523) • Counter oxidative stress induced due to Cisplatin • Protect against urogenital toxicity induced by Cisplatin

IN0523 (Urs-12-ene-3α,24β-diol) a plant based derivative of boswellic acid protect Cisplatin induced urogenital toxicity

Energy Technology Data Exchange (ETDEWEB)

Singh, Amarinder [Academy of Scientific & Innovative Research (AcSIR), New Delhi (India); PK-PD-Toxicology and Formulation Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, J& K (India); Arvinda, S [Deptt. of Pathology, Govt. Medical College, Jammu 180001, J& K (India); Singh, Surjeet [PK-PD-Toxicology and Formulation Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, J& K (India); Suri, Jyotsna [Deptt. of Pathology, Govt. Medical College, Jammu 180001, J& K (India); Koul, Surinder [Bio-Organic Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, J& K (India); Mondhe, Dilip M. [Cancer Pharmacology Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, J& K (India); Singh, Gurdarshan, E-mail: singh_gd@iiim.ac.in [PK-PD-Toxicology and Formulation Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, J& K (India); Vishwakarma, Ram [Bio-Organic Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu 180001, J& K (India)

2017-03-01

The limiting factor for the use of Cisplatin in the treatment of different type of cancers is its toxicity and more specifically urogenital toxicity. Oxidative stress is a well-known phenomenon associated with Cisplatin toxicity. However, in Cisplatin treated group, abnormal animal behavior, decreased body weight, cellular and sub-cellular changes in the kidney and sperm abnormality were observed. Our investigation revealed that Cisplatin when administered in combination with a natural product derivative (Urs-12-ene-3α,24β-diol, labeled as IN0523) resulted in significant restoration of body weight and protection against the pathological alteration caused by Cisplatin to kidney and testis. Sperm count and motility were significantly restored near to normal. Cisplatin caused depletion of defense system i.e. glutathione peroxidase, catalase and superoxide dismutase, which were restored close to normal by treatment of IN0523. Reduction in excessive lipid peroxidation induced by Cisplatin was also found by treatment with IN0523. The result suggests that IN0523 is a potential candidate for ameliorating Cisplatin induced toxicity in the kidney and testes at a dose of 100 mg/kg p.o. via inhibiting the oxidative stress/redox status imbalance and may be improving the efflux mechanism. - Highlights: • Synthesis of a novel boswellic acid derivative (IN0523) • Counter oxidative stress induced due to Cisplatin • Protect against urogenital toxicity induced by Cisplatin.

Critical Parameters and Critical-Region (p,ρ ,T) Data of trans-1,1,1,3-Tetrafluorobut-2-ene [HFO-1354mzy(E)

Science.gov (United States)

Kimura, Takeru; Kayukawa, Yohei; Miyamoto, Hiroyuki; Saito, Kiyoshi

2017-08-01

This study presents the experimental measurement of the pρ T properties and critical parameters of a low GWP type refrigerant, trans-1,1,1,3-Tetrafluorobut-2-ene (HFO-1354mzy(E)). The sample purity of the substance was 99 area %. p ρ T property measurements and visual observations of the meniscus of HFO-1354mzy(E) were carried out using a metal-bellows volumometer with an optical cell. The critical temperature was determined by observation of the critical opalescence. The critical pressure and critical density were determined as the inflection point of the isothermal p ρ T property data at the critical temperature. For more precise clarification of the thermodynamic surface in the vicinity of the critical point, additional p ρ T property measurements were carried out on three isotherms in the supercritical region. The expanded uncertainties (k = 2) in the temperature, pressure, and density measurements were estimated to be less than 3 mK, 1.2 kPa, and 0.32 \\hbox {kg} \\cdot \\hbox {m}^{-3}, respectively. The expanded uncertainties of the critical parameters were estimated to be less than 13 mK, 1.4 kPa, and 2.3 \\hbox {kg} \\cdot \\hbox {m}^{-3}, respectively. These values are the first reported for HFO-1354mzy(E) and are necessary for the development of its equation of state in the near future.

7-{[2-(4-Hydroxyphenylmethylidene]amino}-1,3-thiazol-4-yl-2-(methoxyiminoacetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-ylsulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid

Directory of Open Access Journals (Sweden)

Ghulam Fareed

2012-05-01

Full Text Available Novel 7-{[2-(4-hydroxyphenylmethylidene]amino}-1,3-thiazol-4-yl-2-(methoxyiminoacetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-ylsulfanyl]methyl}-8-oxo-5-thia-1azabicyclo [4.2.0]oct-2-ene-2-carboxylic acid was prepared by condensation of ceftriaxone disodium (1 with 4-hydroxybenzaldehyde (2 in ethanol under reflux conditions for 3–4 h. The structure of synthesized compound was elucidated using LCMS, ¹H-NMR, and CHN techniques.

Areen küsib : mis oli aasta kultuurishokk?

Index Scriptorium Estoniae

2005-01-01

Positiivne ja negatiivne kultuurisündmus 2005. aastal. Küsimusele vastavad Juhan Maiste, Karin Hallas-Murula, Jaan Toomik, Toivo Raidmets, Maile Grünberg, Leo Lapin, Märt Väljataga, Berk Vaher, Sergei Stadnikov, Veljo Kaasik, Margit Mutso, Erkki-Sven Tüür, Mihkel Mutt, Kaarel Tarand, Priidu Beier, Hasso Krull, Jaan Pehk, Hendrik Luuk, Karlo Funk, Kristo Rajasaare, Andres Maimik, Priit Raud, Marianne Kõrver

Tallinna sadamaala linnaruumiline arengukava : ettepanek = Urban Development Plan for the Tallinn Port Area : Proposal

Index Scriptorium Estoniae

2006-01-01

Tellija: Tallinna Linnaplaneerimise Amet. Korraldaja: Eesti Arhitektide Liit. Aeg: 2006. a. veebruar. Osalejad: linnageograaf Hardo Aasmäe, arhitektid Andres Alver, Rein Hansberg, Veljo Kaasik, Ott Kadarik, Erik Konze, Margit Mutso, Tiit Sild, Villem Tomiste, TLPA juht, Tallinna peaarhitekt Igor Volkov, Tallinna Sadama esindaja Hannes Kuhlbach, TLPA projektijuht Jaan Kurm, TLPA üldplaneeringute osakonna juhataja Endrik Mänd, Logi Projekti esindaja Taimi Lokotar, Heldur Meerits

Lahe viisnurkne maja / Urmas Oja

Index Scriptorium Estoniae

Oja, Urmas, 1981-2012

2005-01-01

Eramu (257 m2) Tabasalus. Valge kahekorruselise osaga liitub ühekordne must, oranzhikate triipudega garaazhi ja vannitoaga maht. Terves majas on kasutatud võimalikult palju puitu. Arhitekt Margit Mutso. Sisearhitekt Kätlin Ölluk, kes on kavandanud ka enamiku mööbliesemetest. Projekt 2003, valminud 2005. Ill.: 3 värv. välis- ja 6 sisevaadet, I ja II korruse ning asendiplaan

Nähtamatu naise nähtav panus / Eerik Purje ; fotod: V. Sarapuu

Index Scriptorium Estoniae

Purje, Eerik, 1927-

2006-01-01

17. oktoobri õhtul Tartu College´i saalis toimunud pidulikust õhtust, mis oli pühendatud Vaiki Toile, esitades Roman Toi loomingut ja tähistades Romani 90. sünnipäeva. Õhtut juhtis Avo Kittask, esinesid Estonia Koor, Toronto Eesti Meeskoor, lauluansambel Helin, klaveril saatis Asta Ballstadt, koore juhatasid Margit Viia-Maiste, Ingrid Silm, Charles Kipper. Avati kunstnik Josef Milczarski portree juubilarist

Biologically-Inspired Spike-Based Automatic Speech Recognition of Isolated Digits Over a Reproducing Kernel Hilbert Space

Directory of Open Access Journals (Sweden)

Kan Li

2018-04-01

Full Text Available This paper presents a novel real-time dynamic framework for quantifying time-series structure in spoken words using spikes. Audio signals are converted into multi-channel spike trains using a biologically-inspired leaky integrate-and-fire (LIF spike generator. These spike trains are mapped into a function space of infinite dimension, i.e., a Reproducing Kernel Hilbert Space (RKHS using point-process kernels, where a state-space model learns the dynamics of the multidimensional spike input using gradient descent learning. This kernelized recurrent system is very parsimonious and achieves the necessary memory depth via feedback of its internal states when trained discriminatively, utilizing the full context of the phoneme sequence. A main advantage of modeling nonlinear dynamics using state-space trajectories in the RKHS is that it imposes no restriction on the relationship between the exogenous input and its internal state. We are free to choose the input representation with an appropriate kernel, and changing the kernel does not impact the system nor the learning algorithm. Moreover, we show that this novel framework can outperform both traditional hidden Markov model (HMM speech processing as well as neuromorphic implementations based on spiking neural network (SNN, yielding accurate and ultra-low power word spotters. As a proof of concept, we demonstrate its capabilities using the benchmark TI-46 digit corpus for isolated-word automatic speech recognition (ASR or keyword spotting. Compared to HMM using Mel-frequency cepstral coefficient (MFCC front-end without time-derivatives, our MFCC-KAARMA offered improved performance. For spike-train front-end, spike-KAARMA also outperformed state-of-the-art SNN solutions. Furthermore, compared to MFCCs, spike trains provided enhanced noise robustness in certain low signal-to-noise ratio (SNR regime.

Biologically-Inspired Spike-Based Automatic Speech Recognition of Isolated Digits Over a Reproducing Kernel Hilbert Space.

Science.gov (United States)

Li, Kan; Príncipe, José C

2018-01-01

This paper presents a novel real-time dynamic framework for quantifying time-series structure in spoken words using spikes. Audio signals are converted into multi-channel spike trains using a biologically-inspired leaky integrate-and-fire (LIF) spike generator. These spike trains are mapped into a function space of infinite dimension, i.e., a Reproducing Kernel Hilbert Space (RKHS) using point-process kernels, where a state-space model learns the dynamics of the multidimensional spike input using gradient descent learning. This kernelized recurrent system is very parsimonious and achieves the necessary memory depth via feedback of its internal states when trained discriminatively, utilizing the full context of the phoneme sequence. A main advantage of modeling nonlinear dynamics using state-space trajectories in the RKHS is that it imposes no restriction on the relationship between the exogenous input and its internal state. We are free to choose the input representation with an appropriate kernel, and changing the kernel does not impact the system nor the learning algorithm. Moreover, we show that this novel framework can outperform both traditional hidden Markov model (HMM) speech processing as well as neuromorphic implementations based on spiking neural network (SNN), yielding accurate and ultra-low power word spotters. As a proof of concept, we demonstrate its capabilities using the benchmark TI-46 digit corpus for isolated-word automatic speech recognition (ASR) or keyword spotting. Compared to HMM using Mel-frequency cepstral coefficient (MFCC) front-end without time-derivatives, our MFCC-KAARMA offered improved performance. For spike-train front-end, spike-KAARMA also outperformed state-of-the-art SNN solutions. Furthermore, compared to MFCCs, spike trains provided enhanced noise robustness in certain low signal-to-noise ratio (SNR) regime.

N-O chemistry for antibiotics: discovery of N-alkyl-N-(pyridin-2-yl)hydroxylamine scaffolds as selective antibacterial agents using nitroso Diels-Alder and ene chemistry.

Science.gov (United States)

Wencewicz, Timothy A; Yang, Baiyuan; Rudloff, James R; Oliver, Allen G; Miller, Marvin J

2011-10-13

The discovery, syntheses, and structure-activity relationships (SAR) of a new family of heterocyclic antibacterial compounds based on N-alkyl-N-(pyridin-2-yl)hydroxylamine scaffolds are described. A structurally diverse library of ∼100 heterocyclic molecules generated from Lewis acid-mediated nucleophilic ring-opening reactions with nitroso Diels-Alder cycloadducts and nitroso ene reactions with substituted alkenes was evaluated in whole cell antibacterial assays. Compounds containing the N-alkyl-N-(pyridin-2-yl)hydroxylamine structure demonstrated selective and potent antibacterial activity against the Gram-positive bacterium Micrococcus luteus ATCC 10240 (MIC(90) = 2.0 μM or 0.41 μg/mL) and moderate activity against other Gram-positive strains including antibiotic resistant strains of Staphylococcus aureus (MRSA) and Enterococcus faecalis (VRE). A new synthetic route to the active core was developed using palladium-catalyzed Buchwald-Hartwig amination reactions of N-alkyl-O-(4-methoxybenzyl)hydroxylamines with 2-halo-pyridines that facilitated SAR studies and revealed the simplest active structural fragment. This work shows the value of using a combination of diversity-oriented synthesis (DOS) and parallel synthesis for identifying new antibacterial scaffolds.

Memoriaalkunst / Krista Kodres

Index Scriptorium Estoniae

Kodres, Krista, 1957-

2005-01-01

Eestis uusajal. Surnu kujutisega hauaplaadid. Ballivi hauaplaat (1520) Tallinna Niguliste kirikus. O. Ryningi hauamonument (H. von Aken, 1594) ning P. De la Gardie ja S. Gyllenhielmi hauamonument (A. Passer, 1589-95) Tallinna toomkirikus. Passeri töökoja hauaplastika. 17. sajandi figuraalsed hauaplaadid. Heraldilised hauaplaadid ja tekstitahvlid. Raidkivist epitaafid (A. Passer, J. Winter, J. Hansson, B. Raschky). B. von Roseni kabeli ehissein (F. Hoppenstätt, 1655) Tallinna Niguliste kirikus. C. J Eckesparre perekonna epitaaf-uks (G. Böhme, 18. saj. keskpaik) Kaarma kirikus. J. Hastferi epitaaf (N. Millich?, A. Heroldt?, 1676) Tallinna toomkirikus. 17. sajandi lõpu ja 18. sajandi hauamonumendid (J. G. Stockenberg, J. G. Heroldt). Bilbiograafia lk. 458-460

Synthesis of Pyridine and Spiropyridine Derivatives Derived from 2-aminoprop- 1-ene-1,1,3-tricarbonitrile Together with their c-Met Kinase and Antiproliferative Evaluations.

Science.gov (United States)

Mohareb, Rafat M; Abouzied, Amr S; Abbas, Nermeen S

2018-02-07

Among a wide range of pyridines, 3-cyanopyridines acquired a special attention due to their wide range of pharmacological activities especially the therapeutic activities. Many pharmacological drugs containing the pyridine nucleus were known in the market. The aim of this work was to synthesize target molecules not only possess anti-tumor activities but also kinase inhibitors. To achieve this goal, our strategy was to synthesize a series of 3-cyanopyridine derivatives using 2-aminoprop-1-ene-1,1,3-tricarbonitrile (1) as the key starting material for many heterocyclization reactions. Muticoponent reactions were adopted using compound 1 to get different pyridine derivatives that were capable for different heterocyclization reactions. Antiproliferative evaluations and c-Met kinase, Pim-1 kinse inhibitions were perform where some compounds gave high activities. Compounds that showed high antiprolifeative activity were tested gor c-Met-independent and the results showed that compounds 5c, 5e, 5f, 7c, 7f and 16d were more active than foretinib. The Pim-1 kinase inhibition activity of some selected compounds showed that compounds 5e and 16c were high potent to inhibit Pim-1 activity. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Refractive index effects on the oscillator strength and radiative decay rate of 2,3-diazabicyclo[2.2.2]oct-2-ene.

Science.gov (United States)

Mohanty, Jyotirmayee; Nau, Werner M

2004-01-01

The photophysical properties of 2,3-diazabicyclo[2.2.2]oct-2-ene (DBO) were determined in 15 solvents, two supramolecular hosts (cucurbit[7]uril and beta-cyclodextrin) as well as in the gas phase. The oscillator strength and radiative decay rate of DBO as a function of refractive index i.e. polarizability have been analyzed. The oscillator strength increases by a factor of 10 upon going from the gas phase to the most polarizable carbon disulfide, while the corresponding radiative decay rates increase by a factor of 40. There is a good empirical correlation between the oscillator strength of the weakly allowed n,pi* transition of DBO and the reciprocal bulk polarizability, which can be employed to assess the polarizability of unknown microheterogeneous environments. A satisfactory correlation between the radiative decay rate and the square of the refractive index is also found, as previously documented for chromophores with allowed transitions. However, the correlation improves significantly when the oscillator strength is included in the correlation, which demonstrates the importance of this factor in the Strickler-Berg equation for chromophores with forbidden or weakly allowed transitions, for which the oscillator strength may be strongly solvent dependent. The radiative decay rate of DBO in two supramolecular assemblies has been determined, confirming the very low polarizability inside the cucurbituril cavity, in between perfluorohexane and the gas phase. The fluorescence quantum yield of DBO in the gas phase has been remeasured (5.1 +/- 0.5%) and was found to fall one full order of magnitude below a previously reported value.

Short outlines of books by Estonian authors / Rutt Hinrikus, Janika Kronberg

Index Scriptorium Estoniae

Hinrikus, Rutt, 1946-

2002-01-01

Ehlvest, Jüri. Taevatrepp ; Suuman, Aleksander. Tondihobu tõugud vetikatega ; Õunapuu, Ervin. Mõõk. Nagu jõgi ; Nigov, Anton. Harjutused ; Hainsalu, Lehte. Kellakuuljad ; Heinsaar, Mehis. Härra Pauli kroonikad ; Bristol, Piret. Sajandi öömajad ; Kas kuulete...? : [kuuldemängud] / koost. Tamur Tohver; Rummo, Paul-Eerik. Kohvikumuusikat ; Käsper, Kalle. Vennad Luiged ; Põldroos, Enn. Mees narrimütsiga ; Remsu, Olev. Margit Puusaag ja tema mehed ; Sauter, Peeter. Pori

Rhodium-catalyzed [5 + 2 + 1] cycloaddition of ene-vinylcyclopropanes and CO: reaction design, development, application in natural product synthesis, and inspiration for developing new reactions for synthesis of eight-membered carbocycles.

Science.gov (United States)

Wang, Yi; Yu, Zhi-Xiang

2015-08-18

Practical syntheses of natural products and their analogues with eight-membered carbocyclic skeletons are important for medicinal and biological investigations. However, methods and strategies to construct the eight-membered carbocycles are limited. Therefore, developing new methods to synthesize the eight-membered carbocycles is highly desired. In this Account, we describe our development of three rhodium-catalyzed cycloadditions for the construction of the eight-membered carbocycles, which have great potential in addressing the challenges in the synthesis of medium-sized ring systems. The first reaction described in this Account is our computationally designed rhodium-catalyzed two-component [5 + 2 + 1] cycloaddition of ene-vinylcyclopropanes (ene-VCPs) and CO for the diastereoselective construction of bi- and tricyclic cyclooctenones. The design of this reaction is based on the hypothesis that the C(sp(3))-C(sp(3)) reductive elimination of the eight-membered rhodacycle intermediate generated from the rhodium-catalyzed cyclopropane cleavage and alkene insertion, giving Wender's [5 + 2] cycloadduct, is not easy. Under CO atmosphere, CO insertion may occur rapidly, converting the eight-membered rhodacycle into a nine-membered rhodacycle, which then undergoes an easy C(sp(2))-C(sp(3)) reductive elimination process and furnishes the [5 + 2 + 1] product. This hypothesis was supported by our preliminary DFT studies and also served as inspiration for the development of two [7 + 1] cycloadditions: the [7 + 1] cycloaddition of buta-1,3-dienylcyclopropanes (BDCPs) and CO for the construction of cyclooctadienones, and the benzo/[7 + 1] cycloaddition of cyclopropyl-benzocyclobutenes (CP-BCBs) and CO to synthesize the benzocyclooctenones. The efficiency of these rhodium-catalyzed cycloadditions can be revealed by the application in natural product synthesis. Two eight-membered ring-containing natural products, (±)-asterisca-3(15),6-diene and (+)-asteriscanolide, have been

Occurrence of (Z)-3,4-Dideoxyglucoson-3-ene in Different Types of Beer and Malt Beer as a Result of 3-Deoxyhexosone Interconversion.

Science.gov (United States)

Hellwig, Michael; Nobis, Arndt; Witte, Sophia; Henle, Thomas

2016-04-06

In beer, 3-deoxyglucosone (3-DG) and 3-deoxygalactosone (3-DGal) are important sugar degradation products, but little is known about the relevance of the interconversion reaction between these compounds in different types of beer. In the present study, 3-DG was quantitated at concentrations of 12.9-52.7 mg/L and 3-DGal at concentrations of 6.0-26.4 mg/L in different types of beer (pilsner, wheat, bock, dark, and alcohol-free beers). The concentrations in malt beer tended to be higher. Largely overlapping concentration ranges precluded a classification of beers by their 3-deoxyglycosone contents. 3,4-Dideoxyglucoson-3-ene (3,4-DGE) was identified as an important intermediate and quantitated in beer and malt beer for the first time. The E and Z isomers of the corresponding quinoxaline were synthesized by a new synthetic approach and isolated by semipreparative HPLC. An assay was developed for quantitation of (E)- and (Z)-3,4-DGE by HPLC-MS/MS, and the Z isomer was determined at concentrations of 0.3-1.7 mg/L in beer and 0.5-4.8 mg/L in malt beer samples. The E isomer was shown to be of little importance. Concentrations of 5-hydroxymethylfurfural (HMF) were twice as high as those of (Z)-3,4-DGE in beer samples (0.4-3.7 mg/L) but much higher in malt beer samples (1.6-336 mg/L).

Photo-initiated polymerisation of 1,8-octanedithiol and styrene

International Nuclear Information System (INIS)

Ang, J.B.; Hill, D.J.T.; Pomery, P.J.; Whittaker, A.K.

1998-01-01

Full text: Photo-initiated polymerisation of the thiol-ene system has been well investigated. Its applications include adhesives, coatings and opthalmic lenses. It is unlike the usual UV curable polymeric systems which are predominantly based on acrylates. Typically, acrylate systems are not strictly stoichiometric reactions. The thiol-ene process is a reactive composition based on the stoichiometric reaction of olefins (enes, acrylates) and thiols (mercaptans), which polymerise on exposure to UV light. A unique feature of the thiol-ene system is that the reaction is not inhibited by dissolved or ambient oxygen within the system, thereby eliminating the termination reaction which occurs in acrylate systems. The mechanism of the thiol-ene reaction is a step growth addition process which propagates by a free radical chain mechanism to yield the anti-Markovnikov product scheme. The majority of thiol-ene systems investigated focus on multifunctional moieties of thiol and olefin to produce highly cross-linked networks. This discussion will focus on kinetic information obtained from a linear system comprised of a disfunctional thiol (1,8-octanedithiol) and styrene initiated by a UV light source

The traditional medicine Spilanthes acmella, and the alkylamides spilanthol and undeca-2E-ene-8,10-diynoic acid isobutylamide, demonstrate in vitro and in vivo anti-malarial activity

Science.gov (United States)

Spelman, Kevin; Depoix, Delphine; McCray, Megan; Mouray, Elisabeth; Grellier, Philippe

2010-01-01

Spilanthes spp. are used as traditional herbal medicines in Africa and India to treat malaria. Yet, to date, there is no data on active constituents or most effective extraction methods for this indication. The isolated alkylamides, spilanthol and undeca-2E-ene-8,10-diynoic acid isobutylamide, found in S. acmella Murr., were shown to have IC50s of 16.5 μg/mL and 41.4 μg/mL on Plasmodium falciparum strain PFB and IC50s of 5.8 μg/mL and 16.3 μg/mL for the chloroquine resistant P. falciparum K1 strain, respectively. Further investigations revealed that at relatively low concentrations, spilanthol and the water extract of S. acmella reduced the parasitemia 59% and 53% in mice infected with P. yoelii yoelii 17XNL at 5 mg/kg and 50 mg/kg, respectively. Unexpectedly, the 95% ethanol extract of S. acmella was less effective (36% reduction in parasitemia) at 50 mg/kg. These results provide the first evidence supporting S. acmella against malaria and demonstrating active constituents in S. acmella against P. falciparum. PMID:22692989

C60 and Sc3N@C80(TMB-PPO derivatives as constituents of singlet oxygen generating, thiol-ene polymer nanocomposites

Directory of Open Access Journals (Sweden)

Ashli R. Toles

2016-07-01

Full Text Available Numerous functionalization methods have been employed to increase the solubility, and therefore, the processability of fullerenes in composite structures, and of these radical addition reactions continue to be an important methodology. C60 and Sc3N@C80 derivatives were prepared via radical addition of the photodecomposition products from the commercial photoinitiator TMB-PPO, yielding C60(TMB-PPO5 and Sc3N@C80(TMB-PPO3 as preferred soluble derivatives obtained in high yields. Characterization of the mixture of isomers using standard techniques suggests an overall 1PPO:6TMB ratio of addends, reflecting the increased reactivity of the carbon radical. Although, a higher percentage of PPO is observed in the Sc3N@C80(TMB-PPO3 population, perhaps due to reverse electronic requirements of the substrate. Visually dispersed thiol-ene nanocomposites with low extractables were prepared using two monomer compositions (PETMP:TTT and TMPMP:TMPDE with increasing fullerene derivative loading to probe network structure-property relationships. Thermal stability of the derivatives and the resulting networks decreased with increased functionality and at high fullerene loadings, respectively. TMPMP:TMPDE composite networks show well-dispersed derivatives via TEM imaging, and increasing Tg’s with fullerene loading, as expected for the incorporation of a more rigid network component. PETMP:TTT composites show phase separation in TEM, which is supported by the observed Tg’s. Singlet oxygen generation of the derivatives decreases with increased functionality; however, this is compensated for by the tremendous increase in solubility in organic solvents and miscibility with monomers. Most importantly, singlet oxygen generation from the composites increased with fullerene derivative loading, with good photostability of the networks.

Mustamäe Maarja Magdaleena kiriku arhitektuurivõistlus = Architecture competition for Mustamäe`s Church of Mary Magdalene / Pille Epner

Index Scriptorium Estoniae

Epner, Pille

2013-01-01

Arhitektuurikonkursist, võidutööst "Fiat Lux" (arhitektid Risto Parve, Kai Süda, Martin Kinks, Margit Valma, arhitektuuriteadlane Mait Väljas, Karisma Arhitektid), 2. koha pälvinud tööst "Õhuke Koht" (Pille Noole, Üllar Ambos, Kaisa Lasner, Kerttu Karjust, Jiannis Lykouras, Arhitektuurinurk), 3. koha pälvinud tööst "Tee" (Villem Tomiste, Stuudio Tallinn). Loetletud ostupreemia ja kolm tunnustuse pälvinud võistlustööd

Kuldala elamurajoon : Rae vald, Harjumaa = Kuldala Residential Community : Rae municipality, Harju County / Triin Ojari

Index Scriptorium Estoniae

Ojari, Triin, 1974-

2008-01-01

Arhitektuurne projekt: KOKO Arhitektid. Kutsutud konkurss 2004, autorid: Lembit-Kaur Stöör, Margus Maiste, Raivo Kotov, Tõnis Kimmel. Hoonete projekteerimine: Lembit-Kaur Stöör, Margus Maiste, Olga Batuhtina. Maastikuarhitektuur: Margit Kärner. Projekt: 2005-2006. Lembit-Kaur Stöör arhitektuurikonkursist, planeeringust, elamute arhitektuurist, fassaadidest, ehitusest, sisehoovist. Joonised: vaade, I-IV korruse plaan (2), planeeringu makett, 5 värv. fotot: 3 välis- ja 2 sisevaadet

Simpsonite isa / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2007-01-01

Joonisfilmi "Simpsonite film" ("The Simpsons Movie") maailmaesilinastuste puhul seriaali looja, Kanada päritolu Matt Groeningist ja tema loodud seriaali populaarsuse fenomenist. Lisaks filmi süzheest "Mees peab oma naist kuulama!" (režissöör David Silverman)

Margit Ellinor: forgotten images

Directory of Open Access Journals (Sweden)

Bente Geving

2014-10-01

Full Text Available I began photographing my mother’s room in 2002. Around that time she began changing the arrangements of pictures and ornaments, fetching things out that had been stored in cupboards and drawers, and putting away other things that had previously been features of the room. She assembled various objects on tables, shelves and in cupboards. She tidied and sorted. I became fascinated by the colours of her compositions, and wanted to enter her world.

"Piinakambri" perenaine / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2010-01-01

2009. a. filmiloomingu kuus Oscarit sai Kathryn Bigelow mängufilm "Piinakamber". Selle võiduga on ta esimene naisrežissöör, kes võitnud parima lavastaja auhinna. Sõjafilmist, mille tegevus toimub Iraagis ja mis räägib pommirühma igapäevasest elust

Olla ise / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2008-01-01

Filmisarjas "Ainult friikidele" linastub Tallinnas Sõpruse kinos ja Tartus Athena Keskuses John Cassavetese mängufilm "Naise parimad aastad" ("A Woman Under the Influence") : Ameerika Ühendriigid 1974

Kaks nostalgiatrippi / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2006-01-01

Tantsulavastusest "Once upon" Kanuti Gildi saalis. Idee ja esitus Krõõt Juurak. Jaan Kruusvalli "Võikõllane üü", lavastaja Enn Keerd, muusikalise kujunduse autor Renate Valme, esietendus 14. okt. Endla teatris

Kirgas klaas / Margit Aedla

Index Scriptorium Estoniae

Aedla, Margit, 1970-

2008-01-01

Klaasiga saab ruumi tuua kergust ja värvilise klaasiga lisada pilkupüüdvat aktsenti. Valik klaasist riiuleid (disainerid Aziz Sariyer, Karin Rashid, Jean Nouvel), laevalgusti (disainer Michiko Nakata), seinakell, diivanilaud

Vaimukad vannitoad / Margit Aedla

Index Scriptorium Estoniae

Aedla, Margit, 1970-

2007-01-01

Minimalistlik must vannituba, kus meeleolu saab luua aksessuaaridega või värvilist vuugitäidet kasutades. Avatud duširuumiga vannituba elutoas trepi all. Miniraamatukoguga tualettruum. Klaasist põrand, mille all on värvilised pallid. Kommenteerib Internal Groupi sisearhitekt Anneli Saluste

Baustelle Estland / Margit Mutso

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2001-01-01

Eesti arhitektuurinäitus Saksa kunstiakadeemias Berliinis, eesmärgiks esitada Eesti arhitektuuri ja linnaruumi hetkeseisu. Näitusel osales 18 eesti arhitektuuribürood, ülevaade näituse kujundusest.

Voorus-porno / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2009-01-01

Stephenie Meyeri "Videviku" romaanide sari (Videvik, Noorkuu, Päikesevarjutus, Koidukuma) ja kahe esimese loo ekraniseeringud on fenomenaalselt populaarsed. PÖFFi filmikoolis arutleti teemat kirjandusagent Julian Friedmani juhtimisel. Lisaks kirjastuse Pegasus toimetaja Rene Tendermanni, kirjanik-kirjandusteoreetik Peeter Helme jt. arvamusi

Mehelikkuse kriis / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2009-01-01

Eesti uuemaid lühimängufilme : Sutharsan Bala "Krantsid" (operaator Meelis Veermets, produtsent Marianne Ostrat, osades Jekaterina Novosjolova, Paulo Kulešov ja Mihkel Ulki "Pihv" (stsenarist Triin Sinissaar, osades Mari Abel, Andres Mähar)

Põnev plastik / Margit Aedla

Index Scriptorium Estoniae

Aedla, Margit, 1970-

2008-01-01

Itaalia firma ZERODISEGNO sari Nobody is perfect (plastikvoodi, Guard peegliga, Stacktable, disain: Gaetano Pesce), plastikust tugitool Santa Monica (disain: Denis Santachiara), Casamania polüpropüleenist tool Sue (disain: Cantarutti & Petricich)

Spectral behavior and photophysical parameters of (2Z)-3-[4-(dimethylamino) phenyl]-2-(4-fluorophenyl) prop-2-ene-nitrile (DPF) in different media

Energy Technology Data Exchange (ETDEWEB)

Pannipara, Mehboobali [Department of Chemistry, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589 (Saudi Arabia); Asiri, Abdullah M. [Department of Chemistry, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589 (Saudi Arabia); Center of Excellence for Advanced Materials Research, King Abdulaziz University, Jeddah 21589, P.O. Box 80203 (Saudi Arabia); Alamry, Khalid A. [Department of Chemistry, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589 (Saudi Arabia); Salem, Ibrahim A. [Department of Chemistry, Faculty of Science, Tanta University, 31527 Tanta (Egypt); El-Daly, Samy A., E-mail: samyeldaly@yahoo.com [Department of Chemistry, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589 (Saudi Arabia); Department of Chemistry, Faculty of Science, Tanta University, 31527 Tanta (Egypt)

2015-01-15

A new fluorophore, (2Z)-3-[4-(dimethylamino) phenyl]-2-(4-fluorophenyl) prop-2-ene-nitrile (DPF), was synthesized by knoevenagel condensation of 4-(dimethylamino) benzaldehyde and 4-fluorobenzyl cyanide in ethanol using NaOH as base. The electronic absorption and emission characteristic of DPF were studied in different solvents. The X-ray crystallographic structure of DPF was also investigated. DPF exhibits a red-shift in its emission spectrum as solvent polarity increases, indicating a large change in the dipole moment of dye molecule upon excitation due to intramolecular charge transfer in excited DPF{sup ⁎}. The fluorescence quantum yield depends strongly on the properties of the solvents, which was attributed to positive and negative solvatokinetic effects. A crystalline solid of DPF gives a strong yellow emission at about 532 nm; these phenomena are important for the application of DPF dye in organic photoemitting diode. The photochemical quantum yield of cis–trans isomerization of DPF was also determined in different solvents. The DPF dye displays solubilization in both cationic (CTAB) and anionic (SDS) micelle and may be used as a probe to determine the critical micelle concentration (CMC) of SDS and CTAB. - Highlights: • Organic pi conjugated molecule with a donor acceptor group was studied. • Crystalline solid of the molecule shows strong and intense yellow emission. • The dye displays solubilization in cationic micelle with abrupt change in emission intensity at CMC. • This work gives an insight into the application of organic luminescent material in various fields.

Extra-nodal extension is a significant prognostic factor in lymph node positive breast cancer.

Directory of Open Access Journals (Sweden)

Sura Aziz

Full Text Available Presence of lymph node (LN metastasis is a strong prognostic factor in breast cancer, whereas the importance of extra-nodal extension and other nodal tumor features have not yet been fully recognized. Here, we examined microscopic features of lymph node metastases and their prognostic value in a population-based cohort of node positive breast cancer (n = 218, as part of the prospective Norwegian Breast Cancer Screening Program NBCSP (1996-2009. Sections were reviewed for the largest metastatic tumor diameter (TD-MET, nodal afferent and efferent vascular invasion (AVI and EVI, extra-nodal extension (ENE, number of ENE foci, as well as circumferential (CD-ENE and perpendicular (PD-ENE diameter of extra-nodal growth. Number of positive lymph nodes, EVI, and PD-ENE were significantly increased with larger primary tumor (PT diameter. Univariate survival analysis showed that several features of nodal metastases were associated with disease-free (DFS or breast cancer specific survival (BCSS. Multivariate analysis demonstrated an independent prognostic value of PD-ENE (with 3 mm as cut-off value in predicting DFS and BCSS, along with number of positive nodes and histologic grade of the primary tumor (for DFS: P = 0.01, P = 0.02, P = 0.01, respectively; for BCSS: P = 0.02, P = 0.008, P = 0.02, respectively. To conclude, the extent of ENE by its perpendicular diameter was independently prognostic and should be considered in line with nodal tumor burden in treatment decisions of node positive breast cancer.

Synthesis and Evaluation of in Vitro Biological Activity of 4-Substituted Arylpiperazine Derivatives of 1,7,8,9-Tetrachloro-10,10-dimethoxy-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione

Directory of Open Access Journals (Sweden)

David Collu

2009-12-01

Full Text Available A series of twenty arylpiperazine derivatives of 1,7,8,9-tetrachloro-10,10-dimethoxy-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione have been prepared. These derivatives were tested in vitro with the aim of identifying novel lead compounds active against emergent and re-emergent human and cattle infectious diseases (AIDS, hepatitis B and C, tuberculosis, bovine viral diarrhea. In particular, these compounds were evaluated in vitro against representatives of different virus classes, such as a HIV-1 (Retrovirus, a HBV (Hepadnavirus and the single-stranded RNA+ viruses Yellow fever virus (YFV and Bovine viral diarrhea virus (BVDV, both belonging to the Flaviridae. Compounds 2c, 2g and 3d showed a modest activity against CVB-2. The molecular structures of the starting imide 1 and one of propyl-piperazine derivatives, 3b, have been determined by an X-ray crystallography study.

Korruptsioonikonverents valitsuse ja kolmanda sektori koostöö heaks / Rait Kaarma, Kersti Kurre

Index Scriptorium Estoniae

Kaarma, Rait

2004-01-01

Eesti Maksumaksjate Liidu korraldatud rahvusvahelisest konverentsist "Korruptsioonivastane võitlus Eestis". Väljavõtted Avo Üpruse, Pille Kustovi, Bogdan Senschuki, Anne Schmidti ja Norman Aasa sõnavõttudest

Zinc(II PVC-based membrane sensor based on 5,6-benzo-4,7,13,16,21,24- hexaoxa-1,10-diazabicyclo[8,8,8]hexacos-5-ene

Directory of Open Access Journals (Sweden)

Zamani Hassan Ali

2006-01-01

Full Text Available The 5,6-benzo-4,7,13,16,21,24-hexaoxa-1,10-diazabicyclo[8,8,8]hexacos-5-ene (BHDE was used as an excellent ionophore in construction of a Zn(II PVC-based membrane sensor. The best performance was obtained with a membrane composition of 30% poly(vinyl chloride, 64.5% nitrobenzen (NB, 2.5% BHDE and 3% sodium tetraphenylborate (NaTPB. This sensor shows very good selectivity and sensitivity towards zinc ion over a wide variety of cations, including alkali, alkaline earth, transition and heavy metal ions. The sensor revealed a great enhancement in selectivity coefficients for zinc ions, in comparison to the previously reported zinc sensors. The proposed sensor exhibits a Nernstian behavior (with slope of 29.1 ? 0.4 mV per decade over a wide concentration range (1.0 10-6-1.0 10-1 mol L-1 with a detection limit of 6.3 x10-7 mol L-1 (41.2 ng mL-1. It shows relatively fast response time, in the whole concentration range (< 10s, and can be used for at least 10 weeks in a pH range of 2.8-7.3. The proposed sensor was successfully used in direct determination of zinc ions in wastewater of industrial zinc electroplating companies, and also as an indicator electrode in titration with EDTA.

New optically active and thermally stable poly(amide-imide)s containing N,N'-(Bicyclo[2,2,2]oct-7-ene-2,3,5,6-tetracarboxylic)-bis-L-alanine and aromatic diamines: synthesis and characterization

International Nuclear Information System (INIS)

Faghihi, Khalil; Absalar, Morteza; Hajibeygi, Mohsen

2009-01-01

Five new optically active poly(amide-imide)s (PAIs) 6a-e were prepared by direct polycondensation reaction of the newly synthesized N,N'-(bicyclo[2,2,2]oct-7-ene-2,3,5,6-tetra carboxylic)-bis-L-alanine 4 with various aromatic diamines 5a-e using polar aprotic solvents such as N-methyl-2-pyrrolidone (NMP). In this technique triphenyl phosphite (TPP) and pyridine were used as condensing agents to form poly(amide-imide)s through the N-phosphonium salts of pyridine. All of the polymers were obtained in quantitative yields with inherent viscosities between 0.29-0.46 dL g -1 and were highly soluble in polar aprotic solvents such as N,N-dimethyl acetamide (DMAc), N,N-dimethyl formamide (DMF), dimethyl sulfoxide (DMSO), N-methyl- 2-pyrrolidone (NMP) and solvents such as sulfuric acid. They were fully characterized by means of 1 H NMR, FTIR spectroscopy, elemental analyses, inherent viscosity, solubility test, specific rotation and thermal properties of these polymers were investigated using thermogravimetric analysis techniques (TGA and DTG). (author)

New labdane diterpenes from Solidago canadensis.

Science.gov (United States)

Wangensteen, Helle; Phan, Thi T; Rise, Frode; Halvorsen, Trine G; Malterud, Karl E

2012-01-01

The ethanol extract of roots of Solidago canadensis yielded eight labdane-type diterpenes. Five of those were new natural compounds (9,13,15,16-bisepoxy-labdane-7-ene-6,15-dione (3a), 13-epi-9,13,15,16-bisepoxy-labdane-7-ene-6,15-dione (3b), 15,16-epoxy-labdane-7,13-diene-6,16-dione (5), 15-ethoxy-9,13,15,16-bisepoxy-labdane-7-ene-6-one (6a) and 13-epi-15-ethoxy-9,13,15,16-bisepoxy-labdane-7-ene-6-one (6b). The known labdane diterpenes deoxysolidagenone (1), solidagenone (2) and 15,16-epoxy-labdane-7,13-diene-6,15-dione (4) were also isolated. Chemical structures were determined using 1D and 2D NMR techniques and MS analysis.

Design of peptide substrates for nanosecond time-resolved fluorescence assays of proteases: 2,3-diazabicyclo[2.2.2]oct-2-ene as a noninvasive fluorophore.

Science.gov (United States)

Hennig, Andreas; Florea, Mara; Roth, Doris; Enderle, Thilo; Nau, Werner M

2007-01-15

Fluorescence protease assays were investigated with peptide substrates containing a 2,3-diazabicyclo[2.2.2]oct-2-ene-labeled asparagine (Dbo) as a fluorescent amino acid. The special characteristic of the fluorophore Dbo is its exceedingly long fluorescence lifetime (ca. 300 ns in water under air), which allows the use of nanosecond time-resolved fluorescence (Nano-TRF) detection to efficiently suppress shorter-lived background emission. In addition, the natural amino acids tryptophan and tyrosine can be employed as intramolecular fluorescence quenchers, which facilitates substrate design. Fourteen synthetic peptide substrates (composed of 2-19 amino acids) and five enzymes (trypsin, pepsin, carboxypeptidase A, leucine aminopeptidase, and chymotrypsin) were investigated and, in all 28 examined combinations, enzymatic activity was detected by monitoring the increase in steady state fluorescence with time and determining the reaction rates as kcat/Km values, which ranged from 0.2 to 80x10(6) M-1 min-1. The results suggest an excellent compatibility of the very small and hydrophilic fluorescent probe Dbo with solid-phase peptide synthesis and the investigated proteases. For all 14 peptides the fluorescence lifetimes before and after enzymatic cleavage were measured and Nano-TRF measurements were performed in 384-well microplates. The fluorescence lifetimes of the different peptides provide the basis for the rational design of Dbo-based fluorescent substrates for protease assays. Measurements in Nano-TRF mode revealed, in addition to efficient suppression of background fluorescence, an increased differentiation between cleaved and uncleaved substrate. The Dbo-based assays can be adapted for high-throughput screening.

New optically active and thermally stable poly(amide-imide)s containing N,N'-(Bicyclo[2,2,2]oct-7-ene-2,3,5,6-tetracarboxylic)-bis-L-alanine and aromatic diamines: synthesis and characterization

Energy Technology Data Exchange (ETDEWEB)

Faghihi, Khalil; Absalar, Morteza; Hajibeygi, Mohsen [Arak University (Iran, Islamic Republic of). Faculty of Science. Organic Polymer Chemistry Research Lab.

2009-07-01

Five new optically active poly(amide-imide)s (PAIs) 6a-e were prepared by direct polycondensation reaction of the newly synthesized N,N'-(bicyclo[2,2,2]oct-7-ene-2,3,5,6-tetra carboxylic)-bis-L-alanine 4 with various aromatic diamines 5a-e using polar aprotic solvents such as N-methyl-2-pyrrolidone (NMP). In this technique triphenyl phosphite (TPP) and pyridine were used as condensing agents to form poly(amide-imide)s through the N-phosphonium salts of pyridine. All of the polymers were obtained in quantitative yields with inherent viscosities between 0.29-0.46 dL g{sup -1} and were highly soluble in polar aprotic solvents such as N,N-dimethyl acetamide (DMAc), N,N-dimethyl formamide (DMF), dimethyl sulfoxide (DMSO), N-methyl- 2-pyrrolidone (NMP) and solvents such as sulfuric acid. They were fully characterized by means of {sup 1}H NMR, FTIR spectroscopy, elemental analyses, inherent viscosity, solubility test, specific rotation and thermal properties of these polymers were investigated using thermogravimetric analysis techniques (TGA and DTG). (author)

Uued agulimajad = New Suburb Houses / Andri Ksenofontov

Index Scriptorium Estoniae

Ksenofontov, Andri, 1962-

2005-01-01

Tallinna ajalooliste eeslinnade teke ja kujunemine. Agulite olukord tänapäeval ja haldus viimastel aastatel. Büroo 3+1 projekteeritud ühepereelamu Magasini kvartalis (arhitektid Andres Ojari, Markus Kaasik, Ilmar Valdur, Merje Müürisepp, Kalle Komissarov). Neljakorruseline elamu Õle t. 23/Härjapea t. 14, ühtlasi arhitektide Madis Eegi ja Margit Mutso kodu. Gert Sarve projekteeritud kahepereelamu Herne t. 9. KOKO arhitektide Raivo Kotovi ja Tõnis Kimmeli projekteeritud korterelamu Vabriku t. 33. Ill.: 12 plaani, 14 värv. vaadet

Whats 'App-ening'

DEFF Research Database (Denmark)

Ankersen, Dorit V; Weimers, Petra; Burisch, Johan

2017-01-01

in number. ehealth helps patients in coping with their disease by promoting self-management, which increases adherence to medical treatment and diets, and leads to an improved quality of life. For irritable bowel syndrome (IBS), there are multiple applications that provide dietary advice, for example, a low...

Repliik / Ene Pajula

Index Scriptorium Estoniae

Pajula, Ene, 1950-

2008-01-01

Õpilaskodude foorumist ja õpilaskodudest, mis on loodud kodanikualgatuse korras ja nende inimeste tunnustamise vajadusest, tänu kellele meil on kakskümmend kaheksa õpilaskodu, kus elule tagasi võidetud saab nii mõnigi laps

Ann Tenno salapaigad / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2011-01-01

Fotograaf Ann Tenno aiandushuvist, pildistamisest maailma erinevates paikades. Uutest suundadest (fototöötlus, fractal art, soojuskaameraga pildistamine) tema loomingus. Katkendeid Ann Tenno 2010. aastal ilmunud proosaraamatust "Üle unepiiri"

NYYDi vabastav hingamine / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2009-01-01

Uue muusika festivalil NYYD`09 raames 20. oktoobril Von Krahli Teatris etendunud Märt-Matis Lille kammerooperist "Indiate uurimine", 23. oktoobril Kanuti Gildi saalis Mart Kangro, Taavi Kerikmäe ja Ansambli U koostöös valminud lavastusest "Harmoonia" ja 25. oktoobril Salme Kultuurikeskuses etendunud Heiner Goebbelsi lavastusest "Eraritjaritjaka"

Hinge peegel - keha / Margit Adorf

Index Scriptorium Estoniae

Adorf, Margit, 1974-

2006-01-01

10. PÖFFi filmidest: "Suust suhu" (režissöör Björn Runge; Rootsi - Taani 2005), "Transamerica" (režissöör Duncan Tucer; USA 2005), "Ükski keha pole täiuslik" (režissöör Raphael Sibilla; Prantsusmaa 2006)

Globaalse soojenemise gospel / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2008-01-01

Dokumentaalfilm USA poliitiku Al Gore'i võitlusest keskkonnasäästlikkuse alal "Ebamugav tõde" ("An Inconvenient Truth") : režissöör Davis Guggenheim : Ameerika Ühendriigid 2006, ETV ekraanil 29. aprillil

Enesetapp helesinisel ekraanil / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2008-01-01

Telemängudest, televisiooni võimalikust mõjust inimeste vaimsele tervisele, emotsionaalsele heaolule. Telemängust "Tõehetk", mis ka Eestis on vaadatavuse edetabelites esikohal (Kanal 2). Oma arvamuse ütlevad artiklis "Mis sa oskad kosta?" kirjanik Jan Kaus, ajakirjanik Tiina Kaalep ja sotsioloog Airi-Alina Allaste

Eksperimenteeriv briti kino / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2004-01-01

PÖFFi Suvekino inglise filmide päevad "Geeniuste mäss" pakuvad täna ja homme Tallinnas Katariina kirikus Derek Jarmani filme "Edward II" (1991) ja "Viimne pilk Inglismaale" ("The Last of England", 1987)

Nähtamatud lapsed / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2006-01-01

UNICEFi palvel valmistasid kaheksa tuntud režissööri kassett-filmi maailma kannatavatest lastest "Kõik nähtamatud lapsed" ("All the Invisible Children") : Prantsusmaa - Itaalia 2005. Film on Sõpruse kino kavas

Fassaadikunstist ja teesklusest / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2006-01-01

Soome ja Hiina mütoloogiat ühendav fantaasiafilm "Igavese armastuse sõdalane - Jade Warrior" (Soome, Hiina, Hollandi ja Eesti ühistöö) : stsenarist Iiro Küttner : režissöör Antti-Jussi Annila : võitluskunstide koreograaf Yu Yan Kai : osades Tommi Eronen, Zhang Jingchu, Markku Peltola

Meediaterrorist Chris Morris / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2010-01-01

Briti raadio- ja telesatiirik Christopher Morris ja tema (tele)tegemised seoses kinos Sõprus linastuva islamiäärmuslastest kõneleva komöödiafilmiga "Neli lõvi" (Suurbritannia 2010). Lisaks M. T. "Napid detailid eraelust"

Ameerika vajab kangelasi / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2007-01-01

Näitleja ja režissöör Clint Eastwood. Tema kaks viimast filmi on Teises Maailmasõjas USA-Jaapani Iwo Jima saarel peetud ebavõrdse lahingu teemal. USA poolt vaadatuna - "Meie isade lipud" ("Flags of Our Fathers"), Jaapani poolt - "Kirjad Iwo Jimalt" ("Letters From Iwo Jima") : Ameerika Ühendriigid 2006. Lisaks režissöörist "Eastwood ei kahetse midagi"

Ene-ene-yne Reactions: Activation Strain Analysis and Role of Aromaticity

NARCIS (Netherlands)

Fernandez, I.; Bickelhaupt, F.M.; Cossío, F.P.

2014-01-01

The trend in reactivity of the thermal cycloisomerization reactions of 1,3-hexadien-5-ynes, A=B-C=D-E≡F, were explored and analyzed by using density functional theory at the M06-2X/def2-TZVPP level. These reactions proceed through formally aromatic transition states to form a bent-allene

Inert Reassessment Document for Poly(oxyethylene) adducts of mixed phytosterols

Science.gov (United States)

Poly(oxyethy1ene) adducts of mixed phytosterols is uncategorized as to list classification status. Based upon the reasonable certainty of no harm safety finding, the List 4B classification for poly(oxyethy1ene) adducts of mixed phytosterols is affirmed.

III turismikonverents

Index Scriptorium Estoniae

2006-01-01

Ülevaade Ameerika Ühendriikide suursaadiku Aldona Sofia Wosi, TÜ Pärnu Kolledzhi külalisprofessori James N. Hollerani, Domina World Traveli tegevjuhi Ulvi Tüllineni, OÜ Tallinntuur tegevjuhi Daisy Järva, Hansabussi tegevjuhi Neeme Tammise, Saka Cliff Hotel&SPA OÜ direktori Terje Bürklandi, AS-i Bookinhouse nõukogu esimehe Andres Liinati, majandus- ja kommunikatsiooniministeeriumi siseturuosakonna juhataja Maria Alajõe, EAS-i juhatuse liikme Ülari Alametsa, Säästva Eesti Instituudi kliima ja energeetikaprogrammi projektijuhi Raimo Oinuse, Eesti Giidide Liidu liikme Margit Hallmäe ning zooloog Aleksei Turovski ettekannetest

GC-MS study of Nigella sativa (seeds fatty oil

Directory of Open Access Journals (Sweden)

Mehta, B. K.

2002-06-01

Full Text Available The GC-MS study of N. sativa (seeds fatty oil revealed the presence of 26 compounds which were identified as methyl hept-6-enoate,1-phenylhepta-2,4-dione, pentadecane, hexadec-1-ene, 1-phenyldecan-2-one, octadec-1-ene, octadecane, methyl pentadecanoate, bis(3-chlorophenyl ketone, diethyl phthalate, ethyl octadec-7-enoate, methyl octadecanoate, tricos-9-ene, octadeca-9,12-dienoic acid, hexadecanoic acid, methyl hexadecanoate, methyl octadec-15-enoate, henicosan-10-one, 2-methyl octadecanoic acid, docos-1-ene, ethyl octadecanoate, methyl octadecanoate, pentacos-5-ene,12-methyltricosane, dibutyl phthalate and 2-methyltetracosane.El estudio por GC-MS del aceite de la semilla de Nigella sativa reveló la presencia de 26 compuestos los cuales fueron identificados como: hept-6-enoato de metilo, 1-fenilhepta-2,4-diona, pentadecano, hexadec-1-eno, 1-fenildecan-2-ona, octadec-1-eno, octadecano, pentadecanoato de metilo, bis(3-clorofenil cetona, ftalato de dietilo, octadec-7-enoato de etilo, octadecanoato de metilo, tricos-9-eno, ácido octadeca-9,12-dienoico, ácido hexadecanoico, hexadecanoato de metilo, octadec-15-enoato de metilo, henicosan-10-ona, ácido 2-metil octadecanoico, docos-1-eno, octadecanoato de etilo, octadecanoato de metilo, pentacos-5-eno, 12-metiltricosano, ftalato de dibutilo y 2-metiltetracosano.

Direct Aminolysis of Ethoxycarbonylmethyl 1,4-Dihydropyridine-3-carboxylates

Directory of Open Access Journals (Sweden)

Brigita Vigante

2015-11-01

Full Text Available The ethoxycarbonylmethyl esters of 1,4-dihydropyridines were directly converted into carbamoylmethyl esters in the presence of 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD in good to excellent yields under mild conditions. The use of TBD is crucial for the successful aminolysis of ethoxycarbonylmethyl ester of 1,4-dihydropyridines with secondary amines as without it the reaction does not proceed at all. The aminolysis reaction proceeded regioselectively, as the alkyl ester conjugated with the 1,4-dihydropyridine cycle was not involved in the reaction. Screening of other N-containing bases, such as triethylamine (TEA, pyridine, 4-(N,N-dimethylaminopyridine (DMAP, 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU, 1,5-diazabicyclo[4.3.0]non-5-ene (DBN, imidazole, tetramethyl guanidine (TMG and 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene (MTBD as catalysts revealed no activity in the studied reaction.

Kontserdisari kutsub "Klavessiinisalongi"

Index Scriptorium Estoniae

2008-01-01

Rakvere Kaurikooli saalis toimuvatest kontsertidest: 7. dets."iViva Espagna!" (esinevad klavessiiniduo Ene Nael - Kristiina Are ja näitleja Tarmo Song), 15. veebr. "Häälemeelne" (laulja Kelli Pärnaste ja kitarrist Tiit Korsar, klavessinist Ene Nael) ja 26. apr. "Fiori musicali" (Tallinna Vanalinna Hariduskolleegiumi, Tallinna Muusikakeskkooli ja Rakvere Kaurikooli klavessiiniõpilased)

Nasha "Russkaja galereja" v Madride

Index Scriptorium Estoniae

2005-01-01

Kaasaegse kunsti laat ARCO Madridis. Osaleb "Vene galerii" Tallinnast näitusega TRINITY. Galerist Masha Melnikova. Osalevad Ene-Liis Semper ja Moskva kunstnikud Anton Litvin ning Bogdan Mamonov. Ene-Liis Semper näitab videokunsti, Anton Litvin fotoprojekti ja Bogdan Mamonov realistlikke portreid. Näitus märtsis Vene saatkonna galeriis Tallinnas

"Baltica und Seltene Drucke" in der Akademischen Bibliothek der Universität Tallinn / Helje Kannik

Index Scriptorium Estoniae

Kannik, Helje-Laine

2010-01-01

Tallinna Ülikooli Akadeemilise Raamatukogu Baltika ja haruldaste raamatute osakonna kogust, eesti retrospektiivse rahvusbibliograafia koostamisest, eesti vanaraamatu kohta ilmunud bibliograafiatest ja kajastumisest andmebaasides

The Yellow Star and Everyday Life under Exceptional Circumstances: Diaries of 1944-1945 Budapest

OpenAIRE

Louise O. Vasvári

2016-01-01

In this article, a follow-up of her 2014 contribution in this journal on Hungarian women’s Holocaust diaries, Vasvári discusses six war diaries from 1944-45, which until recently lay forgotten in archives or in private hands. Two of the diaries are by Jewish victims, Anna, Mrs. Sándor Devényi (referred to in the article by her pseudonym, Margit Stellar, Mrs. József Krauss) and Jenő Lévai, who describe their persecution, while the others are by one cleric, Pius István Zimándi, and by three gen...

Arhitektuurikonkursid 2004

Index Scriptorium Estoniae

2004-01-01

Tulemused: Pärnu kergejõustikumaneezh: I preemia - Ralf Lõoke ja Karli Luik; Tartus Raatuse, Pika, Fortuuna ja Põigu tänava vahelise ala hoonestuskava: I - Kai Kuusik ja Taavi Kuri; Aasta betoonehitis 2003: peapreemia - Emil Urbel; Veneetsia IX rahvusvahelise arhitektuuribiennaali "Metamorfoosid" raames eksponeeritava eesti kaasaegse arhitektuuri näituse ideekonkurss: I - Kristjan Holm; äri- ja elumaja Pärnus Aida t. 5: I - Andres Lember; Eesti parim puitehitis 2003-2004: I - Aivo Schults; Eesti parim tellishoone 2003-2004: I- Tiit Trummal; Sõmeru keskusehoone: I - Ralf Lõoke ja Maarja Kask; Eesti Maanteemuuseumi välialade maastikuarhitektuurne ideekonkurss: I - Margit Kärner

Chemical constituents from Aspidosperma illustre (Apocynaceae)

International Nuclear Information System (INIS)

Barbosa, Lara F.; Mathias, Leda; Braz-Filho, Raimundo; Vieira, Ivo J. Curcino

2010-01-01

A new natural product oleanane-type triterpene, olean-12-ene-11α-methoxy-3β-acetate (10) was isolated from Aspidosperma illustre, together with β-amyrin (3), lupeol (4), β-amyrin acetate (5), lupeol acetate (6), olean-12-ene-28-hydroxy-3α-tetradecanoate (7), olean-12-ene-28-carboxy-3α-hexadecanoate (8), ursolic acid (9) triterpenes, and two monoterpenic indole alkaloids, b-yoimbine (1) and 1,2-dehydroaspidospermidine (2). These compounds were characterized on their spectral data basis, mainly one- ( 1 H, 13 C, APT) and two-dimensional ( 1 H- 1 H-COSY, 1 H- 1 HNOESY, HMQC and HMBC) NMR, and mass spectra, involving also comparison with data from the literature. (author)

Three new triterpene esters from pumpkin (Cucurbita maxima) seeds.

Science.gov (United States)

Kikuchi, Takashi; Ueda, Shinsuke; Kanazawa, Jokaku; Naoe, Hiroki; Yamada, Takeshi; Tanaka, Reiko

2014-04-16

Three new multiflorane-type triterpene esters, i.e. 7α-hydroxymultiflor-8-ene-3α,29-diol 3-acetate-29-benzoate (1), 7α-methoxymultiflor-8-ene-3α,29-diol 3,29-dibenzoate (2), and 7β-methoxymultiflor-8-ene-3α,29-diol 3,29-dibenzoate (3), were isolated from seeds of Cucurbita maxima, along with the known compound, multiflora-7,9(11)-diene-3α,29-diol 3,29-dibenzoate (4). Compound 1 exhibited melanogenesis inhibitory activities comparable with those of arbutin. In cytotoxicity assays, compounds 1 and 3 exhibited weak cytotoxicity, with IC50 values of 34.5-93.7 μM against HL-60 and P388 cells.

Three New Triterpene Esters from Pumpkin (Cucurbita maxima Seeds

Directory of Open Access Journals (Sweden)

Takashi Kikuchi

2014-04-01

Full Text Available Three new multiflorane-type triterpene esters, i.e. 7α-hydroxymultiflor-8-ene-3α,29-diol 3-acetate-29-benzoate (1, 7α-methoxymultiflor-8-ene-3α,29-diol 3,29-dibenzoate (2, and 7β-methoxymultiflor-8-ene-3α,29-diol 3,29-dibenzoate (3, were isolated from seeds of Cucurbita maxima, along with the known compound, multiflora-7,9(11-diene-3α,29-diol 3,29-dibenzoate (4. Compound 1 exhibited melanogenesis inhibitory activities comparable with those of arbutin. In cytotoxicity assays, compounds 1 and 3 exhibited weak cytotoxicity, with IC50 values of 34.5–93.7 μM against HL-60 and P388 cells.

Taevo Gans / Ene Ammer

Index Scriptorium Estoniae

Ammer, Ene

1998-01-01

Sisearhitekt Taevo Gansist. Tudengipõlvest, selle aja projektidest, sõpruskonnast, tandemist Summatavet & Gans, Venemaa tellimustest, kaastöölistest. Üksinda Hommilkumaal vene tarbekunsti näitusega 1974. a. 1988. a. loodud perefirmast "GaDis" (omanikud Taevo, Helle Gans, Riia Oja), mis nõustab ka "Wermot" mööbli osas. "GaDise" sisekujundusprojektidest, millega Taevo ja Helle Gans tegelevad üheskoos

Grunge kodukujunduses / Ene Vool

Index Scriptorium Estoniae

Vool, Ene, 1948-

2004-01-01

Low-tech, campi ja grunge ehitus- ja sisustusstiilidest meil ja mujal - kommenteerivad Andro Kööp ja Ain Nurmela. Tutvustatakse ka Mari-Mira projekti Pariisis, mis kujutab endast nn. mutant-küla, putka- ja onnikultuuri koketeriid. Artikli lõpus kommenteerib kunstiteadlane Karin Paulus grungestiili muusikas, riietuses ja sisekujunduses.

LEADER-tegevusest / Ene Sarapuu

Index Scriptorium Estoniae

Sarapuu, Ene

2009-01-01

Läänemaa LEADER-tegevusgrupi eesmärk on maakonna kui terviku ühtne areng, et kogu Läänemaa oleks vajalike teenustega kaetud ning ettevõtjad julgeks ning suudaks uute teenuste ja toodetega turule tulla

Kas fopaa toob õnne? / Margit Adorf

Index Scriptorium Estoniae

Adorf, Margit, 1974-

2007-01-01

PÖFFi avamisest ja mõningatest filmidest: "Asendusõpetaja" (Taani), "See on Inglismaa" (Suurbritannia), "Tühjad pudelid" (rezh. Jan Sverak, Tšehhi), "Viimane armuke" (rezh. Catherine Breillat, Prantsusmaa - Itaalia)

Vaba Läti ehitab / Margit Mutso

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2007-01-01

13.-17.04. 2007 hindas rahvusvaheline žürii Läti parimaid arhitektuuriteoseid. Parim rekonstrueeritud ehitis oli büroohoone Riias Dzirnavu tn. 68 (arhitektid Aleksejs Birjukovs, Andis Silis). Parim tööstushoone oli Ventspilsis asuv mahlakontsentraatide käitlus- ja laohoone (arhitektid Aija Kokina, Andris Kokins, Krista Strelita-Strele). Bürookategooria võiduprojektiks valiti Liepajas Zivju tn. 11/13 paiknev kontorihoone (arhitektid Diana Zalane, Artis Rokis). Parima elamu tiitli pälvis Jurmalas Jura tn. 32 asuv maja (arhitektid Janis Alksnis, Nora Saulespurena, Andris Rubenis). Eramajadest oli parim suvemaja Pavilostas (arhitekt Janis Sauka). Parima maastikuarhitektuur-väikevormi preemia said Gvido Rekis, Anita Neilande, Andris Kausenieks, Didzis Oshenieks Ventspilsi dzhungliraja eest. Sisekujunduspreemia sai originaaldisainiga ekspositsioonikapslitega Grindeksi farmaatsiatoodete näidisteruum Riias

Säästlikud tulevikutooted / Margit Aedla

Index Scriptorium Estoniae

Aedla, Margit, 1970-

2007-01-01

Tutvustatakse Electroluxi disainikonkursi Design Lab žürii poolt välja valitud finaaltöid (külmik GO Fresh, öko-õhupuhastaja Nature Wind, pesumasin e-Wash, plastikut lagundav Return Pot, toiduvalmistusseade Pebble, valamu ja nõudepesumasin Pure Washer, kodune kompostiseade-prügikast Circompo), mis on loodussõbralikud majapidamisseadmed aastaks 2020

Mehed unustatud armeest / Margit-Mariann Koppel

Index Scriptorium Estoniae

Koppel, Margit-Mariann, 1971-

2006-01-01

Dokumentaalfilm "Mehed unustatud armeest" : autor Indrek Treufeldt : režissöör Kalle Käesel : produtsent Renita Timak : ETV ja Osakond OÜ 2006. Film esilinastus Tallinna kinos Sõprus 21. novembril

Sammudes koos Joshua Nelsoniga / Margit Urbel

Index Scriptorium Estoniae

Urbel, Margit

2002-01-01

Pärnu rahvusvahelise dokumentaal- ja antropoloogiafilmide festivali ETV programmis näidatud Ameerika Ühendriikide-Taani-Rootsi muusikalisest dokumentaalfilmist "Lõputult sammudes" ("Keep On Walking")

Restoran Kaerajaan = Kaerajaan Restaurant / Margit Mutso

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2009-01-01

Tallinnas Raekoja plats 17 asuva restorani rahvuslikel motiividel baseeruvast sisekujundusest. Sisearhitektid Janno Roos ja Andres Labi (Ruumilabor). Arhitektuuriajaloolised eritingimused koostas Aleksandr Pantelejev. Lakke ja seinale maalitud muster (Loovool) pälvis Red Dot'i auhinna. Žürii hinnang kultuurikapitali aastapreemiale esitatud sisekujundusele

Seitse teist kevadist hetke / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2010-01-01

Kevadine loodus, VAT Teatri noortele mõeldud lavastus "Kirjaklambritest vöö", Tartu Uue Teatri külalisetendused Tallinnas: Nero Urke lavastuses "Ird, K", Tallinna Ülikooli konverents "Kirjanik kohvriga"

Elurõõmu pillerkaar / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2007-01-01

Pimedate Ööde filmifestivali ja Tartu linna eestvõttel toimuva Tartu vabaõhu filmifestivali "Tartuff - armastuse mitu nägu" filme ("Ükskord", "Harold ja Maude", "Veenus", "Elsa ja Fred"). Lisaks tutvustus "Hollywoodi klassika : "West Side'i lugu" ja "Tristan Priimägi soovitab : "Loomu poolest metsikud""

Tigutorn = The Snail Tower / Margit Mutso

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2010-01-01

Tartus Väike-Turu 5 asuva Tigutorni arhitektuursest lahendusest. Maja alumisel korrusel on äriruumid, ülemistel korrustel korterid. Arhitektid Vilen Künnapu, Ain Padrik, kaasautorid Kristiina Hussar, Kerli Koolma (AB Künnapu & Padrik). Üldruumide kujundus: Heli Eensalu, Sulev Vahtra. Žürii liikme Kalle Komissarovi hinnang kultuurkapitali aastapreemiale esitatud hoonele

Kurjus sirgub piiritundetust individualismist / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit

2007-01-01

Autor arutleb filmi "Klass" ja teiste vägivalda kästlevate noorsoofilmide näitel noorsookultuuri mässulisuse teemal, mis võib põhjustada emotsionaalseid plahvatusi ja isegi vihkamist ja mõtleb, miks Eesti koolisüsteem meenutab rohkem sõjaväge kui loovkeskkonda

Plastiliinivõlur Peter Lord / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2007-01-01

PÖFFi animafilmide festivali "Animated Dreams" ja Nukufilmi 50. juubeli külaline, Bristolis asuva kuulsa Aardman Studio asutajaid ja režissöör Peter Lord oma stuudiost. Lisaks "Jumal on suur animaator, animaator on väike jumal"

Tallinna on tabamas hotellibuum? / Margit Aedla

Index Scriptorium Estoniae

Aedla, Margit, 1970-

2003-01-01

Reval Hotelligrupi tegevdirektor Feliks Mängus analüüsib olukorda Eesti hotelliturul ning leiab, et hotellituru 6-10%-list kasvu viimastel aastatel ei saa pidada plahvatuslikuks, kuna nõudlus on alati liikunud investeerimisotsuste ees.

Tehnilised stiilinäited / Margit Aedla

Index Scriptorium Estoniae

Aedla, Margit, 1970-

2007-01-01

Tutvustatakse LG Art Cool Air Conditioner'i, Electroluxi Global Design sarja sisseehitatavaid tooteid, Zanussi pliiti Teo ja pesumasinat Zoe ning 2007. a. iF disainiauhinna võitnud LG monitiri Fantasy ja LG mobiiltelefoni Chocolate (KG810)

Majandusteadmiste olümpiaad / Margit Luts

Index Scriptorium Estoniae

Luts, Margit

2001-01-01

Junior Achievementì Arengufondi korraldatud majandusteadmiste olümpiaadi piirkondlikel voorudel osales 67 kooli, kaheliikmelisi võistkondi oli 90. Olümpiaadi eelvoorud toimusid üle Eesti 3. märtsil, lõppvoor toimub 7. aprillil Eesti Kõrgemas Kommertskoolis. Sponsorite ja võitjate nimed

Loengud seaduseelnõude koostajaile / Margit Kikas

Index Scriptorium Estoniae

Kikas, Margit

2004-01-01

Eesti Juristide Liidu poolt koostöös Riigikantselei ja Justiitsministeeriumiga korraldatud loengusarjast: Õigusloome ja normitehnika: areng ja probleemid. Sõnavõtjad loengutel: Raul Narits, Katre Kont-Kontson, Lauri Mälksoo, Raigo Sõlg, Jüri Heinla, Anno Aedmaa, Aare Kasemets, Juhani Lemmik, Ülo Siivelt, Külli Koit, Aare Reenumägi, Mall Gramberg, Toomas Sepp, Julia Laffranque, Kristel Aguraiuja, Aime Vettik, Hille Saluäär, Hiie Tamm, Kristina Nõgols, Eve Randvere

Nõia juurde! Vol.2. / Margit Adorf

Index Scriptorium Estoniae

Adorf, Margit, 1974-

2001-01-01

Mängufilmist "Blairi nõiafilm" ("The Blair Witch Project") : stsenaristid ja režissöörid Eduardo Sanchez ja Daniel Myrick : Ameerika Ühendriigid 1999 ja filmi järjest "Varjude raamat : Blairi nõiafilm 2" ("The Blair Witch Project 2") : Ameerika Ühendriigid 2000

Valguse võim Dectonas / Margit Aedla

Index Scriptorium Estoniae

Aedla, Margit, 1970-

2008-01-01

Tallinnas Raua t. asuvast salongist Dectona, kus pakutakse valgusteid, istemööblit ja vaipu. Müügil on eesti disaineri Tarmo Luisu seinavalgustid "Bubble" ja "Hullumeelsus". Salongi juhataja Heidi Kääri kommentaarid

Miinusmärgiga maagia / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2009-01-01

Mehhiko kirjaniku Juan Rulfo novelli "Pedro Paramo" põhjal tehtud Ingomar Vihmari samanimelisest lavastusest Eesti Draamateatris. Kunstnikutöö Ervin Õunapuult, kelle lavakujundust võrreldakse Hendrik Toompere jun. lavastusega "Sada aastat..." Vanemuise laval

Kahekordne austusavaldus suurele hilinejale / Margit Urbel

Index Scriptorium Estoniae

Urbel, Margit

2011-01-01

Portreefilmid Lennart Merest: Jaak Lõhmuse (stsenarist ja režissöör) dokumentaalfilmist "Tantsud Linnuteele. Pildistusi Lennart Meri filmirännakutelt" (Estinfilm ja ERR, 2010) ja Arko Okki dokumentaalfilmist "Monoloogid 3D" ("Man Who Lived in Three-Dimensional Time", Acuba Film koostöös Uljana Kim Studio 2007-2011)

Kae kunstnikku! / Harry Liivrand, Margit Tõnson

Index Scriptorium Estoniae

Liivrand, Harry, 1961-

2007-01-01

Filmiajaloo kümme parimat filmi kunstnikest: Vincente Minnelli "Elujanu", Peter Webber "Tütarlaps pärlkõrvarõngaga", Andrei Tarkovski "Andrei Rubljov", Julie Taymor "Frida", James Ivory "Picasso: looja ja hävitaja", Ed Harris "Pollock", Julian Schnabel "Basquiat", Konrad Wolf "Goya ehk tunnetuse salakaval tee", Raoul Ruiz "Klimt", Oliver Hirschbiegel "Allakäik"

Chemical Constituents from Bombacopsis glabra (Pasq. A. Robyns: Complete 1H and 13C NMR Assignments and X Ray Structure of 5-Hydroxy-3,6,7,8,4'-pentamethoxyflavone

Directory of Open Access Journals (Sweden)

Paula Vanderlúcia F.

2002-01-01

Full Text Available The flavone 5-hydroxy-3,6,7,8,4'-pentamethoxyflavone (1 and the triterpenes lupenone, 9,19-cyclolanost-23-ene-3beta,25-diol (2, (24R-9,19-cyclolanost-25-ene-3beta,24-diol (3 and (24S-9,19-cyclolanost-25-ene-3beta,24-diol (4 were isolated from the hexane extract of the stem bark of Bombacopsis glabra (Bombacaceae. The structures were determined by 13C and ¹H NMR (1D and 2D and mass spectrometry, and by comparison with literature data for triterpenes. The structure of the flavone 1 was unambiguously confirmed by a X-ray diffraction study. The five substances were isolated for the first time from Bombacaceae species.

Situación de riesgo y salud de los adolescentes en el valle de los ríos Apurímac, Ene y Mantaro en Perú

Directory of Open Access Journals (Sweden)

Fabiola Yeckting Vilela

Full Text Available Se presenta el diagnóstico de las condiciones de vida de los adolescentes varones y mujeres en la zona del valle de los ríos Apurímac, Ene y Mantaro (VRAEM, quienes atraviesan situaciones de riesgo y vulnerabilidad social y sexual debido a los altos niveles de producción de la hoja de coca y el contexto del narcotráfico, que crean la ilusión del rápido ascenso social. A partir de ello, es necesario preguntarse ¿cuáles son las condiciones de vida y situaciones de riesgo de los adolescentes en el VRAEM? y ¿cuáles son las alternativas para una mejora de su situación desde el acceso a la educación y los programas de atención de su salud? Esta situación de riesgo es el resultado de las relaciones desiguales de género, violencia sexual, deserción escolar, embarazo adolescente, consumo de alcohol y drogas, así como de la falta de oportunidades como consecuencia de la participación en la economía de la coca y el narcotráfico entre los adolescentes en el VRAEM. Finalmente, se presentan los resultados de la atención de profesionales de los centros de salud para favorecer la consejería en salud sexual y reproductiva y el acceso a los servicios de salud del Programa Vida Adolescente, como oportunidad de vincular los contenidos del currículo de educación y las metas de cumplimiento de este sector, visibilizando la necesidad de un enfoque de interculturalidad e igualdad de género en el acceso a la salud y la educación de los adolescentes.

Senior High School English National Examination and Thinking Skills

Directory of Open Access Journals (Sweden)

Ummu Lathifah Ahmad

2016-12-01

Full Text Available When English National Examination (abbreviated into ENE as a norm-referenced test is designed for instructional purposes, to evaluate the result of national curriculum, it is very significant to conduct item test evaluation since it gives a clear portrait of the quality of the items and of the test as a whole. The purpose of this study was to analyze which levels of the Barrett taxonomy were more reflected in ENE items of 2013/2014 academic year and whether the proportions of items among the twenty test packages in the ENE assessing students’ Lower Order Thinking Skills (LOTS and Higher Order Thinking Skills (HOTS are consistent. The researcher adopted the qualitative descriptive approach using a content analysis card to codify the ENE items. To ensure the reliability of the study, three inter-raters analyzed a sample of the test packages. The results indicated that questions asking LOTS still prevailed in ENE items. Of all the twenty test packages, the items categorized into literal level represented around 68.6% of the total number of the questions. Meanwhile, the questions belonging to reorganization came to occupy a percentage of 20.8 and the questions asking the students’ inferential level only reached 10.3%. Also, the tests were not enriched sufficiently with the evaluation comprehension since they only comprised 0.3%. The results also showed the complete absence of “Appreciation” – the highest level of thinking in the mentioned taxonomy. It is obvious that there is a shortage of items questioning students’ HOTS in the exam and they are not well-treated. Accordingly, this finding reveals that there is still much room for ENE to be the driving force in the effort to make learners critical thinkers. In the light of these data, this study recommends modifying the English National Exam by providing them with more question items that include HOTS.

Mis tulemust teie meeleavalduselt ootate? / Liivi Kulli, Jaanus Gross, Mari-Viivian Laht ... [jt.

Index Scriptorium Estoniae

2011-01-01

Küsimusele vastasid Rakvere reaalgümnaasiumi inglise ja saksa keele õpetaja Liivi Kulli, Turba gümnaasiumi arvutiõpetuse õpetaja Jaanus Gross, Kiltsi põhikooli eesti keele ja kirjanduse õpetaja Mari-Viivian Laht, Ruusa kooli ja Mikitamäe põhikooli inglise keele õpetaja Anne Must, Kunda ühisgümnaasiumi klienditeeninduse õpetaja Evely Press, Tõstamaa keskkooli käsitöö- ja kunstiõpetaja, Inger Vahuvee, prantsuse lütseumi kehalise kasvatuse õpetaja Urmas Kokk, Tõnismäe reaalkooli kehalise kasvatuse õpetaja Mihhail Tõrtõšnõi, Ruila põhikooli inglise keele õpetaja Margit Levoll, ametiühingute keskliidu juht Harri Taliga

Synthesis, characterization and anticancer studies of new steroidal oxadiazole, pyrrole and pyrazole derivatives

Directory of Open Access Journals (Sweden)

Shamsuzzaman

2015-07-01

Full Text Available In the present study steroidal derivatives, 3β-[5′-mercapto-1′,3′,4′-oxadiazole-2-yl]methoxy cholest-5-ene 2, 3β-[2′,5′-dimethylpyrrole-1-yl]aminocarbonylmethoxycholest-5-ene 3 and 3β-[3′,5′-dimethyl pyrazole-1-yl]carbonylmethoxycholest-5-ene 4 have been synthesized from cholest-5-en-3β-O-acetyl hydrazide 1 using CS2/KOH, acetonyl acetone and acetyl acetone, respectively as reagents and are characterized by IR, 1H NMR,13C NMR, MS and elemental analysis. Compounds 2–4 were also evaluated for anticancer activity against human leukemia cell line (HL-60 by MTT assay and compound 4 displayed the promising behavior by showing better anticancer activity.

Effect of tibolone and its principal metabolites (3α- and 3β-hydroxy, 3α-sulfate, and 4-ene derivatives) on estrone sulfatase activity in normal and cancerous human breast tissue.

Science.gov (United States)

Chetrite, Gérard S; Cortes-Prieto, Joaquin; Pasqualini, Jorge R

2011-12-01

Tibolone (Org-OD14) is the active substance of Livial®, a synthetic steroid with the structure 7α,17α-17-hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-one, possessing weak tissue-specific estrogenic, progestogenic, and androgenic properties, used to treat menopausal complaints. After oral administration, tibolone is extensively metabolized into the 3α-(Org-4904) and 3β-(Org-30126) hydroxy derivatives with estrogenic properties, its 4-ene (Org-OM38) isomer with progestogenic/androgenic activities, and the 3α-sulfate (Org-34322) derivative, a major biologically inactive circulating form. We compared the dose response of tibolone and its metabolites on estrone sulfatase activity [conversion of estrone sulfate (E1S) to estrone (E1)] in normal and cancerous human breast tissues. Tissue minces were incubated with physiological concentrations of [3H]-E1S (5×10-9M) alone or in the presence of tibolone and its metabolites (concentration range: 5×10-7to 5×10-5M) for 4 h. Tritiated E1, estradiol (E2), and E1S were separated and evaluated quantitatively by thin-layer chromatography. The sulfatase activity was significantly higher in cancerous breast but strongly inhibited by tibolone and the different metabolites, whereas 3α- and 3β-hydroxy derivatives were the most potent inhibitors. This very significant inhibitory effect of tibolone and its principal metabolites on the enzyme involved in E2biosynthesis in the human breast provides interesting perspectives to study the biological responses of these compounds in trials with breast cancer patients.

Contextual factors and motivators of the accounting developments in Estonian local goverments / Toomas Haldma, Helje Jõgi

Index Scriptorium Estoniae

Haldma, Toomas, 1957-

2006-01-01

Siirdeperioodil on Eesti kohalike omavalitsuste (KOV) süsteem läbi teinud nii finants- kui administratiivreformi, mis mõjutavad majandusarvestuse kontseptuaalseid aspekte. Etapilise lähenemise teoreetilistest seisukohtadest lähtudes analüüsitakse KOV-de arevestussüsteemi arengut läbi Eesti majandusarvestuse kolme arenguetapi

Proof of the Structure of the Stemodia chilensis Tetracyclic Diterpenoid (+)-19-Acetoxystemodan-12-ol by Synthesis from (+)-Podocarpic Acid: X-ray Structure Determination of a Key Intermediate.

Science.gov (United States)

Leonelli, Francesca; Mostarda, Azzurra; De Angelis, Luca; Lamba, Doriano; Demitri, Nicola; La Bella, Angela; Ceccacci, Francesca; Migneco, Luisa M; Marini Bettolo, Rinaldo

2016-04-22

The first synthesis of (+)-19-acetoxystemodan-12-ol (1), a stemodane diterpenoid isolated from Stemodia chilensis, is described. The structure was supported by an X-ray crystallographic analysis of intermediate (+)-9a, which confirmed the proposed structure and excluded the structure of (-)-19-hydroxystemod-12-ene as a possible candidate for the Chilean Calceolaria diterpenoid to which the (-)-19-hydroxystemar-13-ene structure (9b) had been erroneously assigned.

The in vitro biosynthesis of epitestosterone and testosterone from C19 steroid precursors in the testis of the lizard Tiliqua rugosa

International Nuclear Information System (INIS)

Huf, P.A.; Bourne, A.R.; Watson, T.G.

1989-01-01

The metabolism of androgens in the testis of the lizard Tiliqua rugosa has been studied in vitro by incubating cellular homogenates with radiolabeled C19-steroid substrates. The identification 17 beta-oxidoreductase and 3 beta-hydroxysteroid dehydrogenase/isomerase activities. Aromatase, 5 alpha-reductase, and 17 alpha/beta-epimerase activities were not detected. The 17 alpha-oxidoreductase activity was temperature dependent (maximal at 32 degrees), while the 17 beta-oxidoreductase activity was temperature independent. Time yield and dual-label studies indicated that testosterone biosynthesis mainly involves the 4-ene pathway (via androstenedione), whereas the formation of epitestosterone uses both the 4-ene and 5-ene (via 5-androstene-3 beta, 17 alpha-diol) pathways. The function of alternative pathways in androgen biosynthesis is discussed, as is the role of temperature in the intratesticular regulation of androgen production

Transformations in the field of college education

DEFF Research Database (Denmark)

Bøje, Jakob Ditlev

Paperet er kort version af den ene af mine analyser i ph.d.-projektet. Det drejer sig om en historisk diskursanalyse af transformationer af lærer- og pædagoguddnnnelse fra 60'erne til i dag.......Paperet er kort version af den ene af mine analyser i ph.d.-projektet. Det drejer sig om en historisk diskursanalyse af transformationer af lærer- og pædagoguddnnnelse fra 60'erne til i dag....

Project Lifespan-based Nonstationary Hydrologic Design Methods for Changing Environment

Science.gov (United States)

Xiong, L.

2017-12-01

Under changing environment, we must associate design floods with the design life period of projects to ensure the hydrologic design is really relevant to the operation of the hydrologic projects, because the design value for a given exceedance probability over the project life period would be significantly different from that over other time periods of the same length due to the nonstationarity of probability distributions. Several hydrologic design methods that take the design life period of projects into account have been proposed in recent years, i.e. the expected number of exceedances (ENE), design life level (DLL), equivalent reliability (ER), and average design life level (ADLL). Among the four methods to be compared, both the ENE and ER methods are return period-based methods, while DLL and ADLL are risk/reliability- based methods which estimate design values for given probability values of risk or reliability. However, the four methods can be unified together under a general framework through a relationship transforming the so-called representative reliability (RRE) into the return period, i.e. m=1/1(1-RRE), in which we compute the return period m using the representative reliability RRE.The results of nonstationary design quantiles and associated confidence intervals calculated by ENE, ER and ADLL were very similar, since ENE or ER was a special case or had a similar expression form with respect to ADLL. In particular, the design quantiles calculated by ENE and ADLL were the same when return period was equal to the length of the design life. In addition, DLL can yield similar design values if the relationship between DLL and ER/ADLL return periods is considered. Furthermore, ENE, ER and ADLL had good adaptability to either an increasing or decreasing situation, yielding not too large or too small design quantiles. This is important for applications of nonstationary hydrologic design methods in actual practice because of the concern of choosing the emerging

Uloga radnog terapeuta u rehabilitaciji oboljelih od šizofrenije

OpenAIRE

Radić, Saša; Škrbina, Dijana

2011-01-01

Mentalno zdravlje je esencijalni čimbenik za aktivno i neovisno funkcioniranje u svim aspektima života. Poremećaji mentalnog zdravlja značajno narušavaju svakodnevno življenje, te uzrokuju disbalans u tri područja čovjekovih aktivnosti: samozbrinjavanju, produktivnosti i slobodnom vremenu. Odabir, organiziranje i aktivna participacija u produktivnim aktivnostima pojedinca narušenog mentalnoga zdravlja značajno su ograničene i/ili onemogućene zbog smanjene motivacije, nemogućnosti zadovo...

POTENCIJALI PRIMJENE INTEGRIRANIH SUSTAVA UPRAVLJANJA U NAFTNOJ INDUSTRIJI

OpenAIRE

Lulić, Lukša

2014-01-01

S obzirom na svoje posebnosti, određene industrije i sektori moraju posjedovati specifične i rigorozne sustave upravljanja te su u skladu s takvim zahtjevima razvile industrijski specifične zahtjeve i standarde. Razlozi takvih aktivnosti uključuju upravljanje rizicima, spoznaju specifičnih zahtjeva određene industrije, sukladnost sa zakonskim i regulatornim zahtjevima te jačanje povjerenja u proizvode i procese dobavljača. Nafta je polivalentni energent, a naftna industrija podrazumijeva m...

Mõni sõna armastuse puudumisest / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2011-01-01

17. septembril NO99 teatris esietendunud kolme teatri - NO99, Münchner Kammerspiele, Lyric Hammersmith Theatre - koostöös valminud lavastusest "Three Kingdoms" ("Kolm kuningriiki"), teksti autor Simon Stephens, lavastaja Sebastian Nübling

Duši alla sauna / Margit Aedla

Index Scriptorium Estoniae

Aedla, Margit, 1970-

2007-01-01

Duraviti multifunktsionaalne värviline duširuum. Electroluxi Design Lab'07 konkursi finalisti Joao Diego Schimansky Fog Shower (ududuš). Väiksematesse kodudesse sobiv Muoto mobiilne aurusaunatool Muoto-Steam Deluxe

PÖFFi eelsoojendus on tehtud / Margit Adorf

Index Scriptorium Estoniae

Adorf, Margit, 1974-

2006-01-01

PÖFFi laste- ja noortefilmide festivali "Just Film" filmides: "Me saame sellest üle" (rezh. Niels Arden Oplev, Taani 2006), "Tommy põrgu" (rezh. Ove Raymond Gyldenas, Norra), "Pilv" (rezh. Gregor Schnitzler, Saksamaa 2006) ja dokumemtaalfilmist "Kurikuulus". Lisatud nimekiri "Just Film'il" linastunud filmidest põhiprogrammis

PÖFF on poolel teel / Margit Adorf

Index Scriptorium Estoniae

Adorf, Margit, 1974-

2003-01-01

Pimedate Ööde Filmifestivali avalöögiks enne põhifestivali ametlikku algust olid tudengifilmide festival "Sleepwalkers" ja laste- ja noortefilmide festival Just Film. Lähemalt viimasel nähtud kuuest filmist

Valgustuse moraali- ja poliitikafilosoofid inimloomusest / Margit Sutrop

Index Scriptorium Estoniae

Sutrop, Margit, 1963-

1999-01-01

Briti valgustusfilosoofidest. Mandeville'i, Smith'i, Hobbes'i ja Rousseau kaastunde käsitlustest. Locke'i ja Rousseau' võrdlus. Ühiskondliku lepingu teooriast. Rousseau erinevusest briti filosoofidest

Õhtumaa allakäik / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2010-01-01

Eestlaste kaasosalusel vändatud režissöör Chris Krausi filmist "Polli päevikud" (Saksa-Austria-Eesti 2010). Suurem osa "Polli päevikutest" filmiti 2009. a. suvel Pärnumaal Varbla vallas. Muusika autor Annette Focks

Vene filmivirtuoos Dziga Vertov Eestis / Margit Adorf

Index Scriptorium Estoniae

Adorf, Margit, 1974-

2003-01-01

Vene dokumentalistist ja filmiteoreetikust (1896-1954), kelle maailmakuulsat filmi "Inimene filmikaameraga" ("Tshelovek s kinoapparatom") saab näha Tallinnas ja Tartus, saadetuna briti ansamblist The Cinematic Orchestra

Teateid tulevikuköögist / Margit Aedla

Index Scriptorium Estoniae

Aedla, Margit, 1970-

2007-01-01

Electroluci 2006. a. disainiauhinna pälvinud ideetooted: I koht - innovaatiline toiduhoidja Nevale, Metin Kaplan, II - infrapunatehnoloogial põhinev Organic Cook, Brian Law, III - energiasäästlik ja informatiivne pliit Vessto, Eduardo Altamirano, finaali jõudnud töö - maitsetaimede inkubaator HydroSphera

Paide Spordihall = Paide Sports Hall / Margit Mutso

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2010-01-01

Paides Aiavilja 1 asuva spordihalli arhitektuursest lahendusest. Arhitektid: Maarja Kask, Karli Luik, Ralf Lõoke, kaasautor Jaan Port (Salto AB). Sisearhitekt Ville Lausmäe (VL Sisearhitektuur). Žürii liikme Kalle Komissarovi hinnang kultuurkapitali aastapreemiale esitatud hoonele

Lasva veetorn = Lasva Water Tower / Margit Mutso

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2010-01-01

Lasva veetorni rekonstrueerimisest klavertrepiga kunstigaleriiks-vaatetorniks. Arhitekt, idee autor Veronika Valk, kaasautor Kadri Klementi, klavertrepi teostus: Kalle-Priit Pruuden, trepi elektrooniline heli: Kalle Tikas, infostendid: Peeter Laurits. Žürii liige Kalle Komissarov žürii hinnangust EK arhitektuuri sihtkapitali 2009. a. väikeobjekti preemia pälvinud hoonele

Eesti arhitektuur Eesti kultuurifestivalil Pariisis / Margit Mutso

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2011-01-01

25. ja 26. novembril Pariisi Belleville'i arhitektuurikõrgkoolis (Ecole Nationale Supérieure d'Architecture Paris-Belleville) toimunud seminaridest teemadel "Ehitada kaitsealusesse piirkonda", "Tööstussadamate muutumine", "Noored arhitektid. Võistlus kui meetod". Avati Eesti eramajade näitus "50 maja"

Usbeki lastest ja tarbija moraalist / Margit Keller

Index Scriptorium Estoniae

Keller, Margit, 1971-

2007-01-01

Usbekistanis väidetavalt lapstööjõu kasutamisega seoses ütleb autor, et tavaliselt jäävad toodete üle maailma ulatuvad valmistamisahelad tarbija silmale nähtamatuks. Oleks hea, kui tekiks diskussioon, mis ärgitaks kohalikku tarbijat tajuma ja mõtestama oma rolli nii üleilmses kui ka Eesti majanduse ja kultuuriruumi kontekstis

Majandus, planeet või rahakott? / Margit Keller

Index Scriptorium Estoniae

Keller, Margit, 1971-

2009-01-01

Tarbijast ja tarbimisest kriisiajal. Autor vaatleb, kuidas võistlevad ideoloogiad esitavad end praegu halvasti tundvale tarbijale vastuolulisi ootusi ja nõudmisi ning kas selles olukorras on uueks kvaliteediks ja arenguks potentsiaali

Thoughts on public urban space / Margit Mutso

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2009-01-01

Eesti linnaväljakute ja avaliku ruumi toimimisest ja mittetoimimisest seoses nende asukohaga. Analüüsitakse viimase viie aata jooksul loodud ja kavandatud väljakuid ja avalikku ruumi Tallinnas, Rakveres, Pärnus ja Tartus

Filmihullu eluvesi voolab Karlovy Varys / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2010-01-01

Karlovy Vary rahvusvahelisest filmifestivalist. Filmidest "Mr. Nobody" (rež. Jaco Van Dormaeli), "Kasside ema Teresa" (rež. Pawel Sala) ja "The Arbor" (rež. Clio Barnardi). Nimekiri võitnud töödest ja viimastel aastatel festivalil näidatud Eesti mängufilmidest

Romantikutest, armastusega ja ja halastuseta / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2010-01-01

Kolmest suvelavastusest: Tiit Palu dramatiseering Gustave Flaubert'i teosest "Madame Bovary" Endla teatris, Marcel Pagnoli "Tuulesaared", lavastaja Maria Peterson - Theatrum ja MTÜ Arhipelaag Hiiumaal Tahkuna tuletorni all ja Eugene O'Neilli "Iha jalakate all", lavastaja Roman Baskin, MTÜ Kell Kümme Kurgjal Jakobsoni talumuuseumis

Pink läks pikemaks... / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2007-01-01

20. sept. VAT Teatris esietendunud Eesti Muusika ja Teatriakadeemia Lavakunstikooli lavastajate õppesuuna tudengite koolitööst "Pink", mis koosneb kahest iseseisvast loost - Jon Fosse "Talv", lavastaja Robert Annus ja Edward Albee "Loomaaialugu", lavastaja Uku Uusberg. Lisaks küsimus "Aare Toikka, kuidas noored lavastajatudengid VAT Teatri tiiva alla sattusid?"

Kroonitud demagoog ja sajatavad leedid / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2009-01-01

William Shakespeare'i "Kuningas Richard Kolmas", lavastaja Barrie Rutter (Inglismaa), esietendus Vanemuise teatri Sadamateatris 17. oktoobril. Lisaks pealkirjastamata lavastuse tutvustus, autor: E. S.

Tantsud avatud ja suletud ruumis / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2010-01-01

"Vanamees ja meri" Tartu Sadamateatris, (Ernest Hemingway samanimelise lühiromaani alusel), lavastaja-koreograaf-video idee autor ja teostaja Janek Savolainen. "Kehanäppajad" Kanuti Gildi Saalis, idee autor Mihkel Ernits, lavastajad Külli Roosna, Mihkel Ernits

Põrgulikud piinad ja tingimusteta armastus / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2004-01-01

Helsingis 17. korda toimuva festivali "Armastus ja Anarhia" kavas olnud filme - Takashi Miike "Üks vastamata kõne" ("One Missed Call"), korealase Park Chan-Wooki "Vana poiss" ("Old Boy") ja Jean-Luc Godardi "Meie muusika" ("Notre Musique")

Sõnumeid kosmosest / Kristiina Davidjants ; interv. Margit Tõnson

Index Scriptorium Estoniae

Davidjants, Kristiina, 1974-

2007-01-01

2007.a. jaanuari lõpus toimus Hollandis Rotterdamis järjekordne, 36. filmifestival. Festivaliga samal ajal toimunud Rutger Hauer Film Factory's osales Kristiina Davidjants, kellel valmis workshop'i tulemusena lühifilm

Kadriorust leiate pargiraamatukogu / Ene Tamsalu

Index Scriptorium Estoniae

Tamsalu, Ene

2009-01-01

2006. aastal avati Kadrioru Pargi raamatukogu, mille kogu aluseks on soome maastikuarhitektuuri professori Tuula Maria Merivuori pärandatud erialaraamatukogu, kus leiab kirjandust maastiku-, pargi- ja aiaarhitektuurist, linna- ja regionaalplaneerimisest, botaanikast ja aiandusest

Riik arhitektuuritellijana / Ene Läkk

Index Scriptorium Estoniae

Läkk, Ene, 1957-

2010-01-01

Näidete varal Riigi Kinnisvara AS-i korraldatud projekteerimise hangetest, mil välja valiti odavaim pakkumine. Valminud Rakvere politseihoonest ning Jõgeva kohtu- ja politseihoonest. Mudelprojekteerimise (BIM) nõudest. Riigihankest kui salastatud protsessist. Sunnist loobuda autoriõigusest. Riigihankega ühendatud arhitektuurikonkursist

Tohuvabohu kodukujunduses / Ene Läkk

Index Scriptorium Estoniae

Läkk, Ene, 1957-

2000-01-01

Tänapäeva Eesti kodukujundusest. Illustratsiooniks 90ndate kolm eramut : neomodernistlik Sinine Maja neominimalistliku interjööriga (Kolm Pluss Üks Arhitektid, arhitekt M. Kaasik), modernistlik villa Sumberg - (Urbel & Peil, arhitekt E. Urbel, sisekujundaja T. Mähar), ökosugemetega modernistlik villa Koger (arhitekt V. Sova, sisearhitektid A. Teigar, M. Press). Kommenteerivad Mart Kalm, Toivo Raidmets. Terminite selgitus.

Armastus esimesest pilgust / Ene Vool

Index Scriptorium Estoniae

Vool, Ene, 1948-

2005-01-01

Annika Tederi jaapani stiilis aiast kui tähtsast osast eluruumis, mille kujundamisel on abiks olnud Liina Rehepapp. Jaapani aedadest, jaapanlaste suhtumisest aiakunsti ja lisaks artikkel "Eriilmelised ja -otstarbelised jaapani aiad"

Messiuudised : Maison & Objet / Ene Jakobi

Index Scriptorium Estoniae

Jakobi, Ene

2008-01-01

Uusi trende kõige suuremalt disainimessilt Maison & Objet Prantsusmaal - Jean-Charles de Castelbajaci joonistatud toolid, Jean-Christophe Bernardi pleksiklaasist tool ja laud, Joseph Licciardi ja Paul Coheni-Philipp Veenendaali etanoolil põlevad kaminad, Philippe Lebru kellad, Vincenzo Antonuccio vaasid ja Anna Siedlecka ning Radek Achramoviczi täispuhutavad valgustid

Maytenus distichophylla and Salacia crassifolia: source of products with potential acetylcholinesterase inhibition

Directory of Open Access Journals (Sweden)

Fernanda L. Ferreira

Full Text Available ABSTRACT The phytochemical study of the extract leaves from Maytenus distichophylla Mart. and Salacia crassifolia (Mart. ex Schult. G. Don, Celastraceae, resulted in the isolation of 3-oxofriedelane, 3β-hydroxyfriedelane, 3β,24-dihydroxyfriedelane, 3-oxo-28,29-dihydroxyfriedelane, two mixtures of pentacyclic triterpenes (α-amyrin with β-amyrin and 3β-stearyloxy-urs-12-ene with 3β-stearyloxy-olean-12-ene, 3β-palmityloxy-urs-12-ene, the steroid β-sitosterol and its glycosylated derivative β-glucosyl-β-sitosterol, tritriacontanoic acid and the natural polymer gutta percha. The chemical structures of these constituents were established by IR, 1H and 13C NMR spectral data. Crude extracts, the mixtures of triterpenes and the isolated constituents were subjected to in vitro acetylcholinesterase inhibitory evaluation. Acetylcholinesterase inhibitory effect was observed for crude chloroform extract leaves from M. distichophylla (100% and S. crassifolia (97.93 ± 5.63% and for the triterpenes 3β,24-dihydroxyfriedelane (99.05 ± 1.12%, 3-oxo-28,29-dihydroxyfriedelane (90.59 ± 3.76% and 3β-palmityloxy-urs-12-ene (97.93 ± 1.47%. The percent inhibitions induced by these natural products were very similar to those produced by physostigmine (93.94 ± 2.10% a standard acetylcholinesterase inhibitor. Therefore, these results open perspectives for the use of these species as source of compounds with similar physostigmine pharmacological effect.

Estudo fitoquímico da madeira de Guarea macrophylla (Meliaceae Phytochemical study of the wood from Guarea macrophylla (Meliaceae

Directory of Open Access Journals (Sweden)

João Henrique G. Lago

2009-01-01

Full Text Available In the present work, the crude ethanol extract from wood of G. macrophylla was submitted to liquid/liquid partition between hexane, CH2Cl2, EtOAc and n-BuOH. Each phase was individually chromatographed over silica gel, Sephadex LH-20 or Amberlite XAD-2 to give eight terpene derivatives, such as five sesquiterpenoids (caryophyllene oxide, guai-6-en-10β-ol, spathulenol, aromadendrane-4β,10α-diol and aloaromadendrane-4α,10β-diol as well as three triterpenoids (cicloart-24-ene-3β,23(R*-diol, cicloart-24-ene-3β,23(S*-diol, and cicloart-23E-ene-3β,25-diol. Additionally, were isolated three fatty acids (linolenic, linoleic and stearic, two steroids (sitosterol and stigmasterol and sacarose. The structures of all these compounds were characterized by spectrometric analysis, mainly mass spectrometry and NMR and comparison of these data described in the literature.

Rändeandmete kvaliteet ja rändesuundumused Eestis aastatel 2000-2005 = The quality of migration data and the trends of migration in Estonia in 2000-2005 / Alis Tammur, Tiit Tammaru, Ene- Margit Tiit

Index Scriptorium Estoniae

Tammur, Alis

2006-01-01

Eesti statistilise rahvastikuarvestuse alus on olnud viimase rahvaloenduse rahvaarv, millele lisatakse omavalitsusüksuste kaupa registripõhiselt kogutavad sünnid, surmad ning sisse- ja väljaränne. Rahvaloenduse ja rahvastikuregistri andmete põhimõtteline erinevus. Sise- ja välisrände arvestamise probleemid, rändesuundumuste analüüs. Diagramm. Tabelid

EEG POLISOMNOGRAFIJA KAO ZNAČAJNA DIJAGNOSTIČKA I PROGNOSTIČKA METODA ZA PROCJENU OŠTEĆENJA MOZGA U NOVOROĐENČADI I DOJENČADI

OpenAIRE

Paškov Dugandžija, Gordana

2008-01-01

EEG polisomnografija je značajna metoda za dijagnozu i prognozu oštećenja mozga u nedonošene i donošene novorođenčadi i dojenčadi. Sadrži slijedeće elemente: EEG(elektroencefalografija), EOG( elektrookulografija) , EMG( elektromiografija), EKG (elektrokardiografija), respiracija i video monitoriranje. Primjenjujemo polisomnografsku montažu. To je specifično modificiran način postavljanja elektroda. Koristimo posrebrene pločaste elektrode sa 1 metar savitljivim silikonskim odvodima u šest razl...

Teatri aastaauhindade nominendid

Index Scriptorium Estoniae

2006-01-01

Lavastajaauhind : Merle Karusoo, Elmo Nüganen, Tiit Ojasoo, Ene-Liis Semper, Kristian Smeds, Hendrik Toompere jun, Ingomar Vihmar ; kunstnikuauhind : Iir Hermeliin, Liina Keevallik, Ene-Liis Semper, Aime Unt, Ervin Õunapuu ; naisnäitleja auhind : Ülle Kaljuste, Kaie Mihkelson, Harriet Toompere, Marika Vaarik, Liina Vahtrik ; meesnäitleja auhind : Ain Lutsepp, Rein Oja, Rain Simmul, Tarvo Sõmer, Tambet Tuisk, Aarne Üksküla ; Balleti- ja tantsuteater : Marina Tshirkova, Seki Hirotaka, Mari Savitski, Oksana Titova, Taavet Jansen, Sasha Pepeljajev, Katrin Essenson ja Tantsuteater Fine 5

Teatri aastaauhindadele kandideerijad selgunud

Index Scriptorium Estoniae

2006-01-01

Lavastajaauhind : Merle Karusoo, Elmo Nüganen, Tiit Ojasoo, Ene-Liis Semper, Kristian Smeds, Hendrik Toompere jun, Ingomar Vihmar ; kunstnikuauhind : Iir Hermeliin, Liina Keevallik, Ene-Liis Semper, Aime Unt, Ervin Õunapuu ; naisnäitleja auhind : Ülle Kaljuste, Kaie Mihkelson, Harriet Toompere, Marika Vaarik, Liina Vahtrik ; meesnäitleja auhind : Ain Lutsepp, Rein Oja, Rain Simmul, Tarvo Sõmer, Tambet Tuisk, Aarne Üksküla ; Balleti- ja tantsuteater : Marina Tshirkova, Seki Hirotaka, Mari Savitski, Oksana Titova, Taavet Jansen, Sasha Pepeljajev, Katrin Essenson ja Tantsuteater Fine 5

Ülevaade tolli ja käibemaksu teabepäevast / Rait Kaarma, Mariliis Kannukene, Hiie Õunpuu

Index Scriptorium Estoniae

Kaarma, Rait

2004-01-01

30. märtsil toimunud teabepäevast tolli ja käibemaksu teemal. Ülevaade Heli Tariku, Ruth Paade, Lembar Kivistiku, Martin Hubergi ja Kaia Loobi sõnavõttudest. Lisad: kirjalik tollideklaratsioon (SAD) esitatakse, kui ; tollimaksumäärade, keeldude ja piirangutega saab tutvuda

On rates and mechanisms of OH and O3 reactions with isoprene-derived hydroxy nitrates.

Science.gov (United States)

Lee, Lance; Teng, Alex P; Wennberg, Paul O; Crounse, John D; Cohen, Ronald C

2014-03-06

Eight distinct hydroxy nitrates are stable products of the first step in the atmospheric oxidation of isoprene by OH. The subsequent chemical fate of these molecules affects global and regional production of ozone and aerosol as well as the location of nitrogen deposition. We synthesized and purified 3 of the 8 isoprene hydroxy nitrate isomers: (E/Z)-2-methyl-4-nitrooxybut-2-ene-1-ol and 3-methyl-2-nitrooxybut-3-ene-1-ol. Oxidation of these molecules by OH and ozone was studied using both chemical ionization mass spectrometry and thermo-dissociation laser induced fluorescence. The OH reaction rate constants at 300 K measured relative to propene at 745 Torr are (1.1 ± 0.2) × 10(-10) cm(3) molecule(-1) s(-1) for both the E and Z isomers and (4.2 ± 0.7) × 10(-11) cm(3) molecule(-1) s(-1) for the third isomer. The ozone reaction rate constants for (E/Z)-2-methyl-4-nitrooxybut-2-ene-1-ol are (2.7 ± 0.5) × 10(-17) and (2.9 ± 0.5) × 10(-17) cm(3) molecule(-1) s(-1), respectively. 3-Methyl-2-nitrooxybut-3-ene-1-ol reacts with ozone very slowly, within the range of (2.5-5) × 10(-19) cm(3) molecule(-1) s(-1). Reaction pathways, product yields, and implications for atmospheric chemistry are discussed. A condensed mechanism suitable for use in atmospheric chemistry models is presented.

Olefins transformation catalysis by zirconium and tungsten complexes in organic and non-aqueous ionic media; Catalyse de transformation des olefines par les complexes du zirconium et du tungstene en milieux organique et ionique non aqueux

Energy Technology Data Exchange (ETDEWEB)

Laurent-Gerot, P

1997-06-30

Molten salts are suitable solvents for biphasic catalysis: melting butyl-1 methyl-3 imidazolium chloride and aluminium chloride gives a polar and aprotic ionic liquid which is not miscible with hydrocarbons but dissolves organometallic complexes. Two types of complexes have been tested in molten salts with ethyl-aluminium dichloride: zirconium complexes to synthesize light {alpha} olefins from ethene; mono-imido complexes of tungsten VI (Cl{sub 4}W = NAr) to dimerize ethene in but-1 ene and propene in dimethyl-2,3-but-1-ene. For both of these complexes, biphasic catalysis principle is always respected: the active species is present only in the ionic phase and not in the organic phase. The first complexes, biphasic principle is always respected: the active species is present only in the ionic phase and not in the organic phase. The first complexes oligomerize ethene in molten salts with low activity and the {alpha} olefins selectivity is weak. Mono-imido complexes of tungsten VI are proved to be equivalent to the systems composed with WCl{sub 6} and aniline, and they dimerize ethene in but-1 ene and propene in dimethyl-2,3-but-1 ene more efficiently in organic medium than in ionic liquid. The characterization of the active species of the system Cl{sub 4}W=NAr / EtAlCl{sub 2} shows that it is the corresponding mono-imido complex of tungsten 4. (author) 129 refs.

Mõningatest karistusõiguslikest inimese surma põhjustamise, vabaduse võtmise ja kuriteo varjamisega seotud probleemidest : Riigikohtu kriminaalkolleegiumi otsus asjas 3-1-1-57-10 / Erkki Hirsnik

Index Scriptorium Estoniae

Hirsnik, Erkki, 1982-

2011-01-01

Riigikohtu lahendist 3-1-1-57-10: Andres Rannamehe kaitsja vandeadvokaat Veljo Viiloli, Elina Vainovi kaitsja vandeadvokaat Sirje Musta, kannatanute A. M.-i ja A. M.-i esindaja vandeadvokaat Mart Sikuti ning Lõuna Ringkonnaprokuratuuri kassatsioonid Tartu Ringkonnakohtu 8. aprilli 2010. a kohtuotsuse peale kriminaalasjas Andres Rannamehe süüditunnistamises KarS § 117 lg 1, § 118 p 1 ja § 136 lg 1, Edgar Mengeli süüditunnistamises KarS § 121, Elina Vainovi süüditunnistamises KarS § 209 lg 1 järgi ja õigeksmõistmises KarS § 306 lg 1 ja § 307 lg 1 järgi ning Margit Vilgo õigeksmõistmises KarS § 306 lg 1 ja § 307 lg 1 järgi

Agripinin portret u odnosu prema rimskim ženskim portretima s pulskog i nezakcijskog agera

OpenAIRE

Girardi Jurkić, Vesna; Džin, Kristina

2006-01-01

Za vrijeme zaštitnog arheološkog istraživanja (1987.-1988.) na forumu u Puli (Colonia Pola)otkrivena je mramorna ženska glava za koju se pretpostavlja da je portret Agripine Mlađe, ženecara Klaudija i majke cara Nerona. Skulptura je originalno vjerojatno bila postavljena na zidanojbazi u sjeveroistočnom zidu luksuzne prostorije popločene mramorom i ukrašene štukaturama nazidu kojega je baza bila ukrašena mramorom i štukom. Tri natpisa otkrivena u blizini tzv. Agripininekuće spominju careve Kl...

Role of unsaturated derivatives of spermidine as substrates for spermine synthase and in supporting growth of SV-3T3 cells.

OpenAIRE

Pegg, A E; Nagarajan, S; Naficy, S; Ganem, B

1991-01-01

Synthetic unsaturated analogues of the natural polyamine were examined as possible substrates for spermine synthase and as replacements for spermidine in supporting the growth of SV-3T3 cells. It was found that N-(3-aminopropyl)-1,4-diamino-cis-but-2-ene [the cis isomer of the alkene analogue of spermidine] was a good substrate for spermine synthase, but that the trans isomer [N-(3-aminopropyl)-1,4-diamino-trans-but-2-ene] and the alkene analogue [N-(3-aminopropyl)-1,4-diaminobut-2-yne] were ...

Thermal rearrangement of 7-methylbicyclo

Science.gov (United States)

Bender; Leber; Lirio; Smith

2000-08-25

The gas-phase thermal rearrangement of exo-7-methylbicyclo[3.2.0]hept-2-ene yields almost exclusively 5-methylnorbornene products. Inversion (i) of configuration dominates this [1,3] sigmatropic shift although some retention (r) is also observed. Because the [1,3] migration can only occur suprafacially (s) in this geometrically constrained system, the si/sr ratio of 7 observed for the migration of C7 in exo-7-methylbicyclo[3.2.0]hept-2-ene indicates that the orbital symmetry rules are somewhat permissive for the [1,3] sigmatropic migration of carbon.

Antiproliferative Compounds of Cyphostemma greveana from a Madagascar Dry Forest[1

OpenAIRE

Cao, Shugeng; Hou, Yanpeng; Brodie, Peggy; Miller, James S.; Randrianaivo, Richard; Rakotobe, Etienne; Rasamison, Vincent E.; Kingston, David G. I.

2011-01-01

Bioassay-guided fractionation of the EtOH extracts obtained from a plant identified as Cyphostemma greveana Desc. (Vitaceae) led to the identification of one macrolide, lasiodiplodin (1), three sesquiterpenoids, 12-hydroxy-15-oxo-selina-4,1l-diene (2), 1β,6α-dihydroxyeudesm-4(15)-ene (3), and (7R*)-opposit-4(15)-ene-1β,7-diol (5), and the new diterpenoid, 16,18-dihydroxykolavenic acid lactone (4). All the isolates were tested against the A2780 human ovarian cancer cell line, and compound 4 an...

Terpenoid constituents from leaves of Guarea kunthiana

International Nuclear Information System (INIS)

Garcez, Fernanda R.; Garcez, Walmir S.; Bazzo, Rita de Cassia; Silva, Ana Francisca G. da; Resende, Ubirazilda M.

2004-01-01

From leaves of Guarea kunthiana one new kaurene diterpene (ent-kaur-16-en-2-one) was isolated along with eight known diterpenes (ent-kaur-16-ene, ent-3α- and 3β-hydroxykaur-16-ene, kolavelool, kolavenol, kolavenal, ent-13-epi-manoyloxide and (-)-nephthenol), four sesquiterpenes (alismol, alismoxide, spathulenol and 4β,10α-aromadendranediol), polyprenol-12 and α- and δ-tocopherols. Kolavenal is reported for the first time as a natural product, as well as the occurrence of cembrane- and ent-kaurane-type diterpenes in the Meliaceae. (author)

Hydrolysis of strained bridgehead bicyclic vinyl ethers and sulfides

International Nuclear Information System (INIS)

Chwang, W.K.; Kresge, A.J.; Wiseman, J.R.

1979-01-01

Rates of hydrolysis of the bridgehead bicyclic vinyl ether 9-oxabicyclo[3.3.1]non-1-ene(6) and its vinyl sulfide counterpart 9-thiabicyclo[3.3.1]non-1-ene(7), catalyzed by the hydronium ion, were measured in H 2 O and in D 2 O solution. These data give isotope effects, k/sub H//k/sub D/ = 2.4 and 1.9 respectively, which show that these reactions occur by the normal, rate-determining carbon protonation, mechanism. The vinyl ether 6 is less reactive than its olefin analogue, bicyclo[3.3.1]non-1-ene (relative rate 1:1/1400), as may have been expected for a constrained bicyclic system such as this, where stabilization of the bridgehead carbocation intermediate by conjugation with oxygen is severely impaired. The vinyl sulfide 7, however, is even less reactive than the vinyl ether (relative rates 1:1/140); this is a remarkable result in view of the fact that conjugation between the sulfur atom and the cationic center is presumably also strongly inhibited. 1 figure, 3 tables

Hollow Nanospheres Array Fabrication via Nano-Conglutination Technology.

Science.gov (United States)

Zhang, Man; Deng, Qiling; Xia, Liangping; Shi, Lifang; Cao, Axiu; Pang, Hui; Hu, Song

2015-09-01

Hollow nanospheres array is a special nanostructure with great applications in photonics, electronics and biochemistry. The nanofabrication technique with high resolution is crucial to nanosciences and nano-technology. This paper presents a novel nonconventional nano-conglutination technology combining polystyrenes spheres (PSs) self-assembly, conglutination and a lift-off process to fabricate the hollow nanospheres array with nanoholes. A self-assembly monolayer of PSs was stuck off from the quartz wafer by the thiol-ene adhesive material, and then the PSs was removed via a lift-off process and the hollow nanospheres embedded into the thiol-ene substrate was obtained. Thiolene polymer is a UV-curable material via "click chemistry" reaction at ambient conditions without the oxygen inhibition, which has excellent chemical and physical properties to be attractive as the adhesive material in nano-conglutination technology. Using the technique, a hollow nanospheres array with the nanoholes at the diameter of 200 nm embedded into the rigid thiol-ene substrate was fabricated, which has great potential to serve as a reaction container, catalyst and surface enhanced Raman scattering substrate.

Cytochrome P-450-catalyzed desaturation of valproic acid in vitro. Species differences, induction effects, and mechanistic studies

International Nuclear Information System (INIS)

Rettie, A.E.; Boberg, M.; Rettenmeier, A.W.; Baillie, T.A.

1988-01-01

The cytochrome P-450-mediated desaturation of valproic acid (VPA) to its hepatotoxic metabolite, 2-n-propyl-4-pentenoic acid (4-ene-VPA), was examined in liver microsomes from rats, mice, rabbits and humans. The highest substrate turnover was found with microsomes from rabbits (44.2 +/- 2.7 pmol of product/nmol P-450/15 min), while lower activities were observed in preparations from human, mouse, and rat liver, in that order. Pretreatment of animals with phenobarbital led to enhanced rates of formation of 4-ene-VPA in vitro and yielded induction ratios for desaturation ranging from 2.5 to 8.4, depending upon the species. Comparative studies in the rat showed that phenobarbital is a more potent inducer of olefin formation than either phenytoin or carbamazepine. The mechanism of the desaturation reaction was studied by inter- and intramolecular deuterium isotope effect experiments, which demonstrated that removal of a hydrogen atom from the subterminal C-4 position of VPA is rate limiting in the formation of both 4-ene- and 4-hydroxy-VPA. Hydroxylation at the neighboring C-5 position, on the other hand, was highly sensitive to deuterium substitution at that site, but not to deuteration at C-4. Based on these findings, it is proposed that 4-ene- and 4-hydroxy-VPA are products of a common P-450-dependent metabolic pathway, in which a carbon-centered free radical at C-4 serves as the key intermediate. 5-Hydroxy-VPA, in contrast, derives from an independent hydroxylation reaction

Eesti patrioot, kes nägi oma silmaga Dresdeni tulepommitamist ja Nürnbergi protsessi / Chistopher Bollyn, Helje Kaskel

Index Scriptorium Estoniae

Bollyn, Chistopher

2006-01-01

August Kuklane, Võrumaal sündinud eestlane, kelle elusaatusest on kirjutanud ajakirjanikud ajakirjas The Barnes Review. Läbi August Kuklase silmade ja tema poolt läbielatu kaudu saame osa Teise maailmasõja lahingutest, tema teenistusest SS väeüksustes, s.h. Nürnbergi vahipataljonis, elust pagulasena Ameerika Ühendriikides

6-Oxocyclohex-1-ene-1-carbonyl-coenzyme A hydrolases from obligately anaerobic bacteria: characterization and identification of its gene as a functional marker for aromatic compounds degrading anaerobes.

Science.gov (United States)

Kuntze, Kevin; Shinoda, Yoshifumi; Moutakki, Housna; McInerney, Michael J; Vogt, Carsten; Richnow, Hans-Hermann; Boll, Matthias

2008-06-01

In anaerobic bacteria, most aromatic growth substrates are channelled into the benzoyl-coenzyme A (CoA) degradation pathway where the aromatic ring is dearomatized and cleaved into an aliphatic thiol ester. The initial step of this pathway is catalysed by dearomatizing benzoyl-CoA reductases yielding the two electron-reduction product, cyclohexa-1,5-diene-1-carbonyl-CoA, to which water is subsequently added by a hydratase. The next two steps have so far only been studied in facultative anaerobes and comprise the oxidation of the 6-hydroxyl-group to 6-oxocyclohex-1-ene-1-carbonyl-CoA (6-OCH-CoA), the addition of water and hydrolytic ring cleavage yielding 3-hydroxypimelyl-CoA. In this work, two benzoate-induced genes from the obligately anaerobic bacteria, Geobacter metallireducens (bamA(Geo)) and Syntrophus aciditrophicus (bamA(Syn)), were heterologously expressed in Escherichia coli, purified and characterized as 6-OCH-CoA hydrolases. Both enzymes consisted of a single 43 kDa subunit. Some properties of the enzymes are presented and compared with homologues from facultative anaerobes. An alignment of the nucleotide sequences of bamA(Geo) and bamA(Syn) with the corresponding genes from facultative anaerobes identified highly conserved DNA regions, which enabled the discrimination of genes coding for 6-OCH-CoA hydrolases from those coding for related enzymes. A degenerate oligonucleotide primer pair was deduced from conserved regions and applied in polymerase chain reaction reactions. Using these primers, the expected DNA fragment of the 6-OCH-CoA hydrolase genes was specifically amplified from the DNA of nearly all known facultative and obligate anaerobes that use aromatic growth substrates. The only exception was the aromatic compound-degrading Rhodopseudomonas palustris, which uniquely uses a modified benzoyl-CoA degradation pathway. Using the oligonucleotide primers, the expected DNA fragment was also amplified in a toluene-degrading and a m

Stomatološki pregledi tijekom trudnoće

OpenAIRE

Polašek, Antonia

2017-01-01

Trudnoća je jedinstveno vrijeme u životu žene, popraćeno raznovrsnim fiziološkim, anatomskim i hormonskim promjenama koje mogu utjecati na pružanje oralne zdravstvene zaštite. Razumijevanje tih uobičajenih promjena nužno je za pružanje kvalitetne njege trudnica. Međutim, trudnice kao pacijenti nisu medicinski ugrožene i ne bi trebalo odgađati provođenje potrebnog dentalnog tretmana. U trudnoći se javljaju pojedine promjene stanja zubi i okolnog tkiva usne šupljine, ali se one većinom mogu...

Modification of the estrogenic properties of diphenols by the incorporation of ferrocene. Generation of antiproliferative effects in vitro.

Science.gov (United States)

Vessières, Anne; Top, Siden; Pigeon, Pascal; Hillard, Elizabeth; Boubeker, Leila; Spera, Daniela; Jaouen, Gérard

2005-06-16

We report here the synthesis and the strong and unexpected antiproliferative effect of the organometallic diphenolic compound 1,1-bis(4'-hydroxyphenyl)-2-ferrocenyl-but-1-ene (4) on both hormone-dependent (MCF7) and -independent (MDA-MB231) breast cancer cells (IC(50) = 0.7 and 0.6 microM). Surprisingly, 6 [1,2-bis(4'-hydroxyphenyl)-2-ferrocenyl-but-1-ene], the regioisomer of 4, shows only a modest effect on these cell lines. This pertinent organometallic modification seems to trigger an intracellular oxidation of the structurally favorable compound 4, leading to the generation of a potent cytotoxic compound.

Synthesis, antimicrobial and cytotoxicity evaluation of new cholesterol congeners

Directory of Open Access Journals (Sweden)

Mohamed Ramadan El Sayed Aly

2015-10-01

Full Text Available 3β-Azidocholest-5-ene (3 and (3β-3-(prop-2-yn-1-yloxycholest-5-ene (10 were prepared as substrates to synthesize a variety of three-motif pharmacophoric conjugates through CuAAC. Basically, these conjugates included cholesterol and 1,2,3-triazole moieties, while the third, the pharmacophore, was either a chalcone, a lipophilic residue or a carbohydrate tag. These compounds were successfully prepared in good yields and characterized by NMR, MS and IR spectroscopic techniques. Chalcone conjugate 6c showed the best antimicrobial activity, while the lactoside conjugate 27 showed the best cytotoxic effect in vitro.

Three New Multiflorane-Type Triterpenes from Pumpkin (Cucurbita maxima Seeds

Directory of Open Access Journals (Sweden)

Reiko Tanaka

2013-05-01

Full Text Available Three new multiflorane-type triterpenes; 7a-methoxymultiflor-8-ene-3a,29-diol 3-acetate-29-benzoate (1, 7-oxomultiflor-8-ene-3a,29-diol 3-acetate-29-benzoate (2, and multiflora-7,9(11-diene-3a,29-diol 3-p-hydroxybenzoate-29-benzoate (3, were isolated from seeds of Cucurbita maxima, along with three known compounds. Compound 3 and multiflora-7,9(11-diene-3a-29-diol 3-benzoate (5 exhibited potent inhibitory effects on melanogenesis, with low cytotoxicities, and 2 exhibited single-digit micromolar cytotoxicity against HL-60 and P388 cells.

Three new multiflorane-type triterpenes from pumpkin (Cucurbita maxima) seeds.

Science.gov (United States)

Kikuchi, Takashi; Takebayashi, Mika; Shinto, Mayumi; Yamada, Takeshi; Tanaka, Reiko

2013-05-14

Three new multiflorane-type triterpenes; 7a-methoxymultiflor-8-ene-3a,29-diol 3-acetate-29-benzoate (1), 7-oxomultiflor-8-ene-3a,29-diol 3-acetate-29-benzoate (2), and multiflora-7,9(11)-diene-3a,29-diol 3-p-hydroxybenzoate-29-benzoate (3), were isolated from seeds of Cucurbita maxima, along with three known compounds. Compound 3 and multiflora-7,9(11)-diene-3a-29-diol 3-benzoate (5) exhibited potent inhibitory effects on melanogenesis, with low cytotoxicities, and 2 exhibited single-digit micromolar cytotoxicity against HL-60 and P388 cells.

Gender stereotypes analysis in cartoons broadcasted on Croatian televisions

OpenAIRE

Rudančić, Vlatka

2015-01-01

Rodni stereotipi postoje od kada postoje muškarci i žene, njihovo značenje roda i spola. Od samih početaka razvoja pismenosti (od doba Aristotela) muškarci su bili oni koji su išli u lov i čije se mišljenje uvažavalo, dok su žene ostajale doma, rađale djecu i brinule se o njima. Istraživanje se temelji na osamdeset analiziranih crtanih filmova koji se prikazuju na hrvatskim nacionalnim TV postajama te prikazuju postojanje rodnih stereotipa u svim pregledanim materijalima. Metoda koja se koris...

Two new cucurbitane triterpenoids from the seeds of Momordica charantia.

Science.gov (United States)

Ma, Lin; Yu, Ai-Hua; Sun, Li-Li; Gao, Wan; Zhang, Meng-Meng; Su, Ya-Lun; Liu, Hua; Ji, Teng-Fei; Li, Di-Zao

2014-01-01

Two new cucurbitane triterpenoids 1 and 2 were isolated, together with six known compounds, from the seeds of Momordica charantia L. The structures of new compounds were determined to be 3-O-{[β-d-galactopyranosyl(1 → 6)]-O-β-d-galactopyranosyl}-23(R), 24(R), 25-trihydroxycucur-bit-5-ene (1), 3-O-[β-d-galactopyranosyl]-25-O-β-d-galactopyranosyl-7(R), 22(S), 23(R), 24(R), 25-pentahydroxycucurbit-5-ene (2), respectively. Their structures were elucidated by the combination of mass spectrometry, one- and two-dimensional NMR experiments and chemical reactions.

Teaduse ja ühiskonna vahelised pinged / Margit Sutrop

Index Scriptorium Estoniae

Sutrop, Margit, 1963-

2005-01-01

Saksa-Eesti akadeemilise nädala raames toimunud teaduskonverentsist, mille teemaks oli "Teadus ja teadmistepõhine ühiskond". Konverentsi humaniora sektsioon oli pühendatud teaduse ja ühiskonna vahelistele pingetele

Rohelise maa uus film vallutab Euroopat / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2004-01-01

Iiri filmiprogrammis "Green Screen", mille on koostanud Iiri Filmiinstituut ja Iiri Filminõukogu Euroopa Liitu astuvate riikide jaoks, võib kinos "Sõprus" näha kaheksat uuemat filmi. Tutvustavalt kolmest mängufilmist : Kirsten Sheridani "Diskopõrsad", Liz Gilli "Kuldkala mälu" ja Aisling Walshi "St Jude'i vangid"

Kitman haarab uusi turge ja tegevusvaldkondi / Margit Aedla

Index Scriptorium Estoniae

Aedla, Margit, 1970-

2005-01-01

Eesti kapitalil põhineva kaubandussisustust tootva AS-i Kitman arengust. Ettevõtte juhatuse esimees Ilo Rannu peab edukuse põhjusteks paindlikkust ja tootedisaini, eesmärgiks on saada lähiaastatel täislahendust pakkuvaks sisustusettevõtteks

Zombilood / Robert Kirkman ; intervjueerinud Margit Tõnson, Peeter Helme

Index Scriptorium Estoniae

Kirkman, Robert

2010-01-01

Režissöör George A. Romero kultusfilmid zombidest "Elavate surnute öö", "Surnute koidik", "Surnute päev" jpt. on inspiratsiooniks koomiksikirjutaja Robert Kirklandile. Režissöör Frank Darabont on teinud tema tuntuimast koomiksiseeriast "The Walking Dead" teleseriaali "Kõndivad surnud". Zombiteema kasvavast populaarsusest ning intervjuu koomiksikirjutajaga

Hull aeg nõuab segaseid inimesi? / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2011-01-01

Režissöör Shinya Tsikamoto film "Kotoko" (Jaapan, 2011), Urszula Antoniaki "Kood: sinine" (Taani-Hollandi 2011), Lisa Aschani "Ahviplikad" (Rootsi 2011), Oliver Hermanuse "Puhas ilu" (Lõuna-Aafrika, 2011) ja Andrei Zvjagintsevi "Jelena" (Venemaa, 2011) Pimedate Ööde Filmifestivalil

Fikseeritud intress pole laenajate seas populaarne / Margit Aedla

Index Scriptorium Estoniae

Aedla, Margit, 1970-

2004-01-01

Eerika Vaikmäe-Koit ja Triin Messimas Eesti Ühispangast selgitavad, kuidas kujunevad fikseeritud ja ujuv intress ning arutlevad võimalike põhjuste üle, miks inimesed siiani vastupidiselt keskpanga soovitustele ujuva intressi kasuks otsustavad. Lisa: Kui palju kulub sissetulekust laenudele?

Vene Kultuurikeskus = The Russian Culture Centre / Margit Mutso

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2010-01-01

Tallinnas Mere puiestee 5 asuva hoone (arhitekt A. Kuznetsov, 1954) restaureerimisest. Arhitekt Niina Mäger, sisearhitekt Anne Tamverk. Ajaloolane Aleksandr Pantelejev. Žürii liikme Mait Summataveti hinnang kultuurkapitali aastapreemiale esitatud hoonele

Viljandi sõudeelling = Viljandi Rowing Slipway / Margit Mutso

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2010-01-01

Viljandis Ranna pst. 13 asuva sõudeellingu arhitektuursest lahendusest. Arhitektid Lauri Saar, Toomas Paaver, Indrek Järve (Paik Arhitektid OÜ), kaasautorid Jaak-Adam Looveer, Tõnu Laanemäe. Žürii liige Kalle Komissarov žürii hinnangust kultuurkapitali aastapreemiale esitatud ehitisele

Tallinna Loomeinkubaator = Creative Incubator in Tallinn / Margit Mutso

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2010-01-01

Tallinnas Veerenni 24C asuva Tallinna Loomeinkubaatori sisekujundusest. Sisearhitektid Raul Tiitus, Tarmo Piirmets (Pink OÜ), graafiline kujundus: Kaarel Vahtramäe (Velvet Studio). Žürii liikme Mait Summataveti hinnang kultuurkapitali aastapreemiale esitatud sisekujundusele

Ökomaterjalid - mida, kuhu ja miks? / Margit Kool

Index Scriptorium Estoniae

Kool, Margit

2008-01-01

Looduslikud materjalid korteris või eramus, maa- või linnakodus, puu- või kivimajas. Kork, puit, sisal, kookoskuid, mererohust põrandakate, linoleum, savikrohv, lubikrohv, tadelakt, kohupiimavärv, lubivärv, savivärv, puitpaneelid, laudis, tapeet. 11 värv. ill.

Inside : küpse sisustaja oaas / Margit Aedla

Index Scriptorium Estoniae

Aedla, Margit, 1970-

2008-01-01

Tallinnas Lootsi tänaval asuvast sisustussalongist Inside ja seal pakutavast mööblist, valgustitest jm. Salong on sisustatud näidiskoduna ning mõeldud kogenumale ja jõukale sisustajale. Kommenteerib omanik Jana Tool

Vabatrupp näitas meeleheite hiiglasi / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2005-01-01

11. märtsil esietendus teatris NO98 ja Sine Loco (A. Türnpu projekt) koostöös lavastus "Inimese teekond", mille lähtematerjaliks on J. Bunyani religioosne teos "Palveränduri tee". Lavastaja ja kokkupanija A. Türnpu

Palju rääkimata lugusid / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2006-01-01

Aafrika kultuuri ja ühiskonda käsitlevad filmide tegijateks on enamasti valged autorid, kelle käsitlused on stereotüüpsed. Ebatüüpiline näide on parima võõrkeelse filmi Oscari võitnud Gavin Hoodi "Tsotsi" : Lõuna-Aafrika 2005

Pilk praktikale = A look at practice / Margit Argus

Index Scriptorium Estoniae

Argus, Margit, 1981-

2015-01-01

Essee teemaks on ajalooliste hoonete renoveerimine ja neisse uute funktsioonide loomine. Lähemalt on vaadeldud Tartu Ülikooli Ajaloo muuseumit, mis tegutseb Tartu Toomkiriku varemetes ja Energia Avastuskeskust Tallinn Elektrijaama hoones

Väikelinna filmipidu / Margit Vremmert ; interv. Mari Laaniste

Index Scriptorium Estoniae

Vremmert, Margit

2006-01-01

Locarno filmifestalist, kus võistles ka Eesti, Läti ja Sloveenia koostööfilm "Koer, lennuk ja laulupidu" ("Kilnieks/The Hostage") : režissöör Laila Pakalnina. Kuldse Leopardi võitis Šveitsi - Saksamaa koostööfilm "Preili" ("Das Fräulein"), režissöör Andrea Staka

Läti Rahvusliku Kunstimuuseumi hoone uuendamisest / Margit Mutso

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2010-01-01

Läti Rahvusliku Kunstimuuseumi (saksa arhitekt Wilhelm Neumann) rekonstrueerimise ja laienduse rahvusvahelisest avalikust arhitektuurivõistlusest. 1. koha pälvinud Leedu arhitektuuribüroo Processoffice ja 2. koha saanud Eesti arhitektuuribüroo Salto lahendustest

Kümme teed maailma lõppu / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2009-01-01

Kümme apokalüptilist filmi: animafilm "Wall-E" (režissöör Andrew Stanton), ulmefantaasia "Inimlapsed" ("Children of Men", režissöör Alfonso Cuaron), "Matrix" triloogia (režissöörid Andy ja Larry Wachowski), "12 ahvi" ("Twelve Monkeys", režissöör Terry Gilliam), "Dr. Strangelove ehk kuidas ma lõpetasin muretsemise ja õppisin armastama pommi" ("Dr. Strangelove", režissöör Stanley Kubrick), "Päikesepaiste" ("Sunshine", režissöör Danny Boyle), "Maximum Overdrive" (režissöör Stephen King), "Pöidlaküüdi teejuht galaktikasse" ("Hitchhiker's Guide to the Galaxy", režissöör Garth Jennings), "Maailmade sõda" ("War of the Worlds", režissöör Steven Spielberg) ja "2012" (režissöör Roland Emmerich, USA 2009)

Veneetsia filmifestival ilmutas auhindu jagades tolerantsi / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2005-01-01

62. Veneetsia filmifestivali auhinnasaajad. Parima filmi Kuldlõvi sai Ang Lee "Brokebacki mägi", žürii eripreemia Abel Ferrara (artiklis "Ferrera") "Mary", parimaks naisnäitlejaks tituleeriti Giovanna Mezzogiorno, Marcello Mastroianni nimelise noore näitleja preemia sai Menothy Cesar

Aiamaja = Residential building in Aia street / Margit Mutso

Index Scriptorium Estoniae

Mutso, Margit, 1966-

2010-01-01

Tallinnas vanalinna piiril Vana-Viru 13/Aia 4 asuva elamu arhitektuursest lahendusest. Arhitektid: Villem Tomiste, Ott Kadarik, Mihkel Tüür (AB Kosmos). Ajaloolane Liivi Künnapu. Žürii liige Kalle Komissarovi žürii hinnangust kultuurkapitali aastapreemiale esitatud hoonele

Kunstnikuks pühitsemine Hype Gallery's / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2004-01-01

Londonis Old Truman Brewery galeriihoones Hewlett Packardi toetusel kunstiprojekt kuni 28. veebrarini 2004, mille raames loomingulised inimesed saavad end määratleda kunstnikuna. Ainus limiteeriv kriteerium on tähtede HP olemasolu pealkirjas. Kübergaleriisse saadetud töö prinditakse ja riputatakse vana õlletehase seintele

Hamletid Krahli proovisaalis - remixed and revisited / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2006-01-01

"Hamletid" William Shakespeare'i ainetel Von Krahli Teatri väikeses saalis. Kontseptsioon, lavastus, koreograafia, kujundus, valgus Sasha Pepeljajev, video, heli, elektroonika Taavet Jansen. Esitaja Juhan Ulfsak. Esietendus 3. okt

Investeerimine on arusaadav ja popp teema / Margit Aedla

Index Scriptorium Estoniae

Aedla, Margit, 1970-

2005-01-01

Sampo Baltic Asset Managementi müügitoetuse juhi Peeter Schamardini sõnul ei peaks inimesed võtma endale maksimaalset laenumakset võimalikult lühikeseks perioodiks, vaid normaalse suurusega ja pikema ajaperioodi peale

Catherine Breillat vabastab naisi filmikunsti kaudu / Margit Tõnson

Index Scriptorium Estoniae

Tõnson, Margit, 1978-

2005-01-01

Berliini 55. filmifestivali Talent Campusel seksuaalstseenide filmimisest kõnelnud prantsuse režissööri vaadetest ühiskondlike normide ja filmikunsti vahekorrale, pornograafiale, mida audiovisuaalses kultuuris ei eksisteerivat

Presencia del Cancionero Popular Infantil en la literatura española de la Edad de Oro

Directory of Open Access Journals (Sweden)

Cerrillo Torremocha, Pedro

2013-12-01

Full Text Available Margit Frenk pointed out the textual coincidences between popular and ‘traditional’ songs included in literary works from the 15th to the 17th Centuries and certain folk songs that have survived and are still used now or until quite recently. This encouraged the author of this paper to trace the utilization of traditional children’s songs and verses in literary works by Spanish authors of the 16th and 17th Centuries. These compositions occasionally date from the Middle Ages and, with the invention of printing, were recorded in writing and incorporated into educated literary works. Many of these compositions can still be found in children’s games and practices today. They have survived the passage of time though popular memory. This study looks at those popular children’s songs which have been included, either entirely or in part, in the literary works of renowned authors of the 16th and 17th Centuries.Margit Frenk ha señalado coincidencias textuales entre canciones de tipo popular y ‘tradicional’, incluidas en obras literarias del XV al XVII, y ciertas canciones folclóricas vivas en nuestros días o que se pudieron recoger hasta hace pocos años. Esta afirmación nos animó a rastrear la presencia de canciones y retahílas de tradición infantil en obras de autores españoles del XVI y XVII: composiciones que, en ocasiones, provienen de la Edad Media y que, tras la invención de la imprenta, en algunos casos se fijaron por escrito y se incluyeron en obras literarias cultas. Hoy bastantes de esas composiciones están vivas en juegos y prácticas infantiles. Es un proceso de pervivencia en la memoria popular de la infancia. En este trabajo nos referimos a composiciones del Cancionero popular infantil y que aparecen, completas o en algunos de sus versos, en obras literarias del XVI y XVII, algunas de autores muy significativos.

Uus eesti disain / Ene Läkk

Index Scriptorium Estoniae

Läkk, Ene, 1957-

2009-01-01

2009. a. disainiöö raames toimunud Eesti Disainerite Liidu algatatud konkursi "Eesti disain ja elukeskond 2009" disainikategooria kümne finalisti tööde tutvustus. 1. koha sai moodulrattahoidja "Rohi" (disain: Keha3), 2. koha vurr-tool "Kiirendi" (disain: Jaanus Orgusaar), 3. koha lastemööbel "Smart kid" (disain: Pavel Sidorenko, Heiki Must)

Modernne kastmaja Nõmmel / Ene Läkk

Index Scriptorium Estoniae

Läkk, Ene, 1957-

1999-01-01

Projekteerija: arhitektuuribüroo Mark & Tamm. Konstruktiivne osa: inseneribüroo Randväli Karema. Arhitektid Ülar Mark, Kalle Komissarov. Kahekorruseline maja Vabaduse pst. ääres on mahutatud puude vahele kitsale alale. Kommenteerib Ü. Mark.

Ametlikke annetusi 2005. aastal / Ene Riet

Index Scriptorium Estoniae

Riet, Ene, 1954-

2005-01-01

Saksamaa suursaadik Julius Bobinger kinkis 50 saksakeelset "Kalevipoega" Eesti Kultuuriministeeriumile, kes edastas need maakonnaraamatukogudele, teadusraamatukogudele ja Kreutzwaldi muuseumile Võrus

Professor Pekka Puska loengud / Ene Indermitte

Index Scriptorium Estoniae

Indermitte, Ene, 1967-

2004-01-01

Soome Rahvatervishoiu Instituudi direktor, Põhja-Karjala projekti juht prof Pekka Puska peab Tartu ülikoolis loengu "The North Karelia Projekt in Finland and lessons for global chronic disease prevention"

Tagasivaade elule ja ajale / Ene Liivik

Index Scriptorium Estoniae

Liivik, Ene, 1933-

2010-01-01

Artikkel põhineb kahel käsikirjal "Tagasi waade möödunud elule ja ajale. Utškuju-Tarhani küla aja lugu. 50ne aastane juubel" ja "Lahtised lehed", mille autoriks on Helmi Koolmann. Käsikirjas meenutavad Helmi ja tema abikaasa Rein Koolmann Krimmis elatud aastaid

Hüdra aastasada / Ene-Reet Soovik

Index Scriptorium Estoniae

Soovik, Ene-Reet

1997-01-01

Arvustus: Galsworthy, John. Peatüki lõpp : Üle jõe / tlk. Jüri ja Liisi Ojamaa. Tallinn : Eesti Raamat, 1997; Amis, Kingsley. qnneseen Jim / tlk. Urve Hanko. Tallinn : Eesti Raadio, 1997; Boyd, William. Sinine pärastlõuna / tlk. Virve Krimm. Tallinn : Varrak, 1997. Briti XX saj. kirjanduse ülevaade

Küberjulgeolekule teed rajades / Ene Ergma

Index Scriptorium Estoniae

Ergma, Ene, 1944-

2007-01-01

Riigikogu esimees analüüsib aprillisündmustega kaasnenud küberrünnakute kui ühe terrorismi erivormi tagamaid, toob välja vajaduse kujundada küberrünnakute suhtes Euroopa Liidus ja NATO-s ühtne poliitika

Eesti Etnograafia Ring Kanadas / Ene Runge

Index Scriptorium Estoniae

Runge, Ene, 1919-1999

1993-01-01

Etnograafia Ring looodi 1971.a ja on pidevalt õpetanud käsitööd, pidanud loenguid eesti ja inglise keeles, korraldanud näitusi ja loonud eesti sektsiooni Royal Ontario Museumi ja Canadian National Museumi juurde kultuurivara säilitamiseks. Seltsi 20. aastapäevaks oli välja antud 61 õppekirja, lisaks õpetused ajakirjas "Triinu" ja õppefilmid, fotod ja diapositiivid, abi on antud samasugustele ringidele Rootsis ja Austraalias, ERM-ile saadeti 1991. a üle 200 rahvakultuuri eseme

ŽENE U ZNANOSTI: STAKLENI STROP

OpenAIRE

PRIJIĆ-SAMARŽIJA, Snježana; AVELINI HOLJEVAC, Ivanka; TURK, Marko

2009-01-01

Temeljni cilj članka jest propitivanje postojanja "staklenoga stropa" ili podzastupljenosti žena na rukovodećim položajima u ustanovama znanosti i visokog obrazovanja kakvo je Sveučilište u Rijeci, uključivo i mehanizama koji ga uzrokuju. Prvi dio članka sadrži kratak pregled i analizu empirijskih rezultata istraživanja provedenog na Sveučilištu u Rijeci, koji nedvojbeno upućuju na prisutnost efekta "staklenoga stropa" i, shodno tome, na postojanje prikrivene primarne i s...

Arquetipos populares, arquetipos cultos y sagrada escritura en la poesía popular española

Directory of Open Access Journals (Sweden)

Teresa Herraiz de Tresca

2001-11-01

Full Text Available Many traditions come across in the ballads collected by Margit Frenk under the epigraph: "Que si soy morena", those referred to celebrations of the Virgin and those concerned with subjects of amorous nature. These traditions are related to the paneuropean subject -inquired by the same scholar- of the brown colour's affirmation, the tradition of fair beauty, associated to the learned and noble level, even including the clearly blond and green-eyed subject-studied by Faral, Lecoy, Dámaso Alonso and María Rosa Lida- and finally an evident biblical presence, especially present at the Carmina carminorum. Because of the intense diffusion and comments on this biblical book in monasteries -especially those of Benedictines and Cisternians- and in the Marian liturgy, there are many ways of interpenetration with popular culture,

Pro-demokraatlik interventsioon : [bakalaureusetöö] / Rait Kaarma ; Tartu Ülikooli Õigusinstituut ; juhendaja: René Värk

Index Scriptorium Estoniae

Kaarma, Rait

2003-01-01

Demokraatia ja rahvusvaheline õigus, õiguse demokraatiale areng, sõjalise jõu kasutamine klassikalises sõjalises õiguses, pro-demokraatliku interventsiooni doktriin, unilateraalne ja kollektiivne pro-demokraatlik interventsioon

Ene Üleoja: "Kreeki ei ületa praegu keegi" / Ene Üleoja ; intervjueerinud T[iina] M[attisen

Index Scriptorium Estoniae

Üleoja, Ene, 1937-

2010-01-01

Heliloojate Liidu ja Pirita kloostri poolt välja kuulutatud heliloominguvõistluse "Taaveti laul" tulemustest žürii liikme E. Üleojaga. Konkursi lõppkontsert toimus 10. veebr. Pirita kloostris, esines Voces Musicales Endrik Üksvärava juhatusel

Mechanical Characterization of Polydopamine-Assisted Silver Deposition on Polymer Substrates

Science.gov (United States)

Cordes, Amanda Laurence

Inspired by the adhesive proteins in marine mussels, polydopamine has become a popular adhesive ad-layer for surface functionalization of a variety of substrates. Based on the chemistry of the dopamine monomer, amine and thiol functional groups are hypothesized to increase adhesion between polymer substrates and polydopamine thin films. This hypothesis was the central motivation for development of a tailorable thiol-ene system in order to study the effects of substrate chemistry on polydopamine adhesion. While polydopamine-adhered silver has been studied on a variety of substrates, no in depth mechanical characterization has been performed and to date, no research has been published on thiol-enes coated in polydopamine-adhered silver. The purpose of this study was to characterize the mechanical durability and adhesion properties of a polydopamine-adhered silver film on commercial substrates and a tailorable thiol-ene system. Polydopamine and silver coatings were deposited on a variety of polymer substrates through a simple dip-coat process. The polydopamine forms a thin uniform adhesive layer and the silver deposits in a discontinuous manner with a nanoparticle sized base layer covering the full surface and micron-sized clusters adhered sporadically on top. Mechanical tensile testing was performed to characterize the durability of the silver coating on commercial polymers. Coated nylon and HDPE showed no signs of degradation or delamination of the polydopamine-adhered silver coating up to 30% strain although both substrates showed large plastic deformation. Peel tests were performed on both commercial polymers as well as a tailorable thiol-ene system. Results support the hypothesis that polydopamine adhesion is increased with the presence of functional groups. Parts of the HDPE sample were cleanly peeled, but silver patches were left sporadically across the surface pointing to weaker adhesion between polyethylene and polydopamine. A high adhesive strength tape was

National Energy Strategy 2012-2026; Estrategia Nacional de Energia 2012-2026

Energy Technology Data Exchange (ETDEWEB)

Direccion General de Planeacion Estrategica, Secretaria de Energia, Mexico, D.F. (Mexico)

2012-02-15

In compliance with the provisions of the Congress, the National Energy Strategy 2012-2026 (NES) outlines the direction of the Mexican energy sector with a horizon of 15 years. Its vision is supported by a comprehensive planning exercise that collects information from each of the parastatals and decentralized administrative bodies that make up the sector. This ensures the accuracy and relevance of information presented throughout the document and integrates the perspectives of all public bodies involved. From that interagency and interdisciplinary approach, the NES provides energy policy guidelines that are essential to realize this vision. In turn, these serve to construct detailed criteria of public policy. Finally, the NES raises specific targets for 2026, which can be achieved based on the implementation of actions considered within the planning guidelines. The NES is a prospective tool and indicative that stands as a useful tool for any plan or program. To serve as an instrument of dialogue between institutions and authorities, NES is a document with a solid vision and a planned role in Mexico's energy policy. [Spanish] En cumplimiento por lo establecido por el Congreso de la Union, la Estrategia Nacional de Energia 2012-2026 (ENE) delinea el rumbo del sector energetico mexicano con un horizonte de 15 anos. Su vision esta sustentada en un ejercicio integral de planeacion que recaba informacion de cada una de las entidades paraestatales y organos administrativos desconcentrados que conforman el sector. Esto garantiza la precision y pertinencia de la informacion presentada a lo largo del documento e integra las perspectivas de todos los entes publicos involucrados. A partir de ese enfoque interinstitucional e interdisciplinario, la ENE establece los lineamientos de politica energetica que son indispensables para materializar esta vision. A su vez, estos sirven para construir criterios detallados de politica publica. Finalmente, la ENE plantea metas concretas

Exposure to volatile organic compounds in an ethanol and gasoline service station.

Science.gov (United States)

de Oliveira, K M P G; Martins, E M; Arbilla, G; Gatti, L V

2007-08-01

The present study was conducted to determine the VOCs concentrations in a service station located in a residential and commercial area in the city of Rio de Janeiro. This is, to our knowledge, the first published determination in Brazil, where both ethanol and ethanol-blended gasoline are used. Electro polished, stainless steel, evacuated canisters were used for sampling. The analysis was performed by gaschromatography with flame ionization detection (CG-FID) and by gas chromatography-mass spectrometry (CG-MS). A total of 80 and 56 compounds were determined in samples collected at the service station and control location, respectively. The most abundant compounds at the service station were in order of decreasing concentration (units: microg m(-3)): 2-methylbutane (1,715.7), 2-methylbut-1-ene (1,043.2), isobutene (758.8), 2-methylprop-1-ene (703.7), 2-methylpentane (492.1), pentadi-1,3-ene (189.7), toluene (157.0), benzene (144.5), but-2-ene (126.3) and m,p-xylene (123.2). A mean concentration of 144.5 microg m(-3) was determined for benzene, this value is about ten times the concentration determined in the control location in this work and about 70 times the value determined in other locations of Rio de Janeiro using charcoal cartridges for the sampling. The mean benzene/toluene ratios are 0.92 and 0.31 in the service station and control location, respectively. Since in Brazil service station workers are employed to fill customer's cars (self-service is not commonly used) the possible risk of cancer of these workers should be evaluated in a future study.

FY 2001 report on the results of the survey of the environmentally friendly type energy community project. Feasibility survey of the commercialization of the gasification melting system use heat supply business using container packing waste plastic and other waste as raw materials; 2001 nendo kankyo chowa gata energy komyuniti jigyo. Gaska yoyu system wo mochiita yoki hoso kei hai purasuchikku oyobi sonota no haikibutsu wo genryo to suru netsu kyokyu jigyo no jigyoka F/S chosa chosa hokokusho

Energy Technology Data Exchange (ETDEWEB)

NONE

2002-03-01

As to gasification melting facilities (Eco-Ene center) using container packing waste plastic and other waste as raw materials in 'the Eco-town Kochi City - Business Project,' study/evaluation of environmental conservation and business profitability were conducted. In Eco-Ene Center, power generation (power supply to users: 1,295 kW) and heat supply (27 GJ/h at maximum) are conducted using the gas product obtained from the combustion of waste. The environmental effect of introduction of Eco-Ene Center is as follows: energy conservation: 51,350-113,594 GJ/y, environmental pollution gas reduction: 1,128-4,987 t-CO2, 1,441-6,691 kg-NOx, 2,965-6,447 kg-SOx, 27,309 {mu}g-TEQ/m{sup 3} dioxin. As a result of the study of economical efficiency, the following was found out: In securing the ending cash balance such as personnel expenses, land lease cost and transportation cost, the subject is the acceptance price of container packing plastic from which a half of the profit can get, and it is necessary to receive subsidy for 1/2 of the price and reduce operating expenses. (NEDO)

Four new neolignans isolated from Eleutherococcus senticosus and their protein tyrosine phosphatase 1B inhibitory activity (PTP1B).

Science.gov (United States)

Zhang, Le; Li, Ban-Ban; Li, Hao-Ze; Meng, Xiao; Lin, Xin; Jiang, Yi-Yu; Ahn, Jong-Seog; Cui, Long

2017-09-01

Four new compounds, erythro-7'E-4-hydroxy-3,3'-dimethoxy-8,5'-oxyneoligna-7'-ene-7,9-diol-9'-al (1), (7S,8S)-4-hydroxy-3,1',3'-trimethoxy-4',7-epoxy-8,5'-neolign-9-ol (5), (7S,8S,7'E)-5-hydroxy-3,3'-dimethoxy-4',7-epoxy-8,5'-neolign-7'-ene-9,9'-diol (6) and (7S,8S,7'E)-5-hydroxy-3,3',9'-trimethoxy-4'-7-epoxy-8,5'-neolign-7'-ene-9-ol (7). Along with four known compounds (2-4, 8) were isolated from the EtOAc-soluble extract of Eleutherococcus senticosus. Their structures were elucidated on the basis of spectroscopic and physicochemical analyses. All the compounds were evaluated for in vitro inhibitory activity against PTP1B, VHR and PP1. Among them, compounds 1-4 and 6-8 were found to exhibit selective inhibitory activity on PTP1B with IC 50 values ranging from 17.2±1.6 to 32.7±1.2μM. Copyright © 2017 Elsevier B.V. All rights reserved.

Androgen and Progesterone Receptors Are Targets for Bisphenol A (BPA, 4-Methyl-2,4-bis-(P-HydroxyphenylPent-1-Ene--A Potent Metabolite of BPA, and 4-Tert-Octylphenol: A Computational Insight.

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Mohd Rehan

Full Text Available Exposure to toxic industrial chemicals that have capacity to disrupt the endocrine system, also known as endocrine disrupting chemicals (EDCs, has been increasingly associated with reproductive problems in human population. Bisphenol A (BPA; 4,4'-(propane-2,2-diyldiphenol and 4-tert-octylphenol (OP; 4-(1,1,3,3-tetramethylbutylphenol are among the most common environmental contaminants possessing endocrine disruption properties and are present in plastics, epoxy resins, detergents and other commercial products of common personal and industrial use. A metabolite of BPA, 4-Methyl-2,4-bis(4-hydroxyphenylpent-1-ene (MBP is about 1000 times more biologically active compared to BPA. Epidemiological, clinical, and experimental studies have shown association of BPA and OP with adverse effects on male and female reproductive system in human and animals. The endocrine disruption activity can occur through multiple pathways including binding to steroid receptors. Androgen receptor (AR and progesterone receptor (PR are critical for reproductive tract growth and function. Structural binding characterization of BPA, MBP, and OP with AR and PR using molecular docking simulation approaches revealed novel interactions of BPA with PR, and MBP and OP with AR and PR. For BPA, MBP, and OP, five AR interacting residues Leu-701, Leu-704, Asn-705, Met-742, and Phe-764 overlapped with those of native AR ligand testosterone, and four PR interacting residues Leu-715, Leu-718, Met-756, and Met-759 overlapped with those of PR co-complex ligand, norethindrone. For both the receptors the binding strength of MBP was maximum among the three compounds. Thus, these compounds have the potential to block or interfere in the binding of the endogenous native AR and PR ligands and, hence, resulting in dysfunction. The knowledge of the key interactions and the important amino-acid residues also allows better prediction of potential of xenobiotic molecules for disrupting AR- and PR

Skønhed og rædsel i den nye Pharma Science Building

DEFF Research Database (Denmark)

Reeh, Henrik

2016-01-01

Reportage fra et fælles besøg i den nyligt indviede PharmaScience Building, Københavns Universitet, juni 2016. Teksten om mødet mellem journalist og forsker på den ene side og bygningen og dens brugere på den anden side. Journalist Christoffer Zieler henviser til Henrik Reehs separat offentliggjo......Reportage fra et fælles besøg i den nyligt indviede PharmaScience Building, Københavns Universitet, juni 2016. Teksten om mødet mellem journalist og forsker på den ene side og bygningen og dens brugere på den anden side. Journalist Christoffer Zieler henviser til Henrik Reehs separat...

Lipid constituents of the red alga Acantophora spicifera

Digital Repository Service at National Institute of Oceanography (India)

Wahidullah, S.; DeSouza, L.; Govenkar, M.B.

to report another novel steroid cholest-4-ene-3:~, 6/3- diol (4), cholest-4-ene-3-one (1), lauric acid or dode- canoic acid (3) and o-phthalic acid bis-(2 ethyl nonyl)- ester (2). RESULTS AND DISCUSSIONS Compound 1 had tH NMR (CDC13) spectrum....p. 46 C and the formula of Ct2H2402 was assigned on the basis of its mass spectrum which showed peaks at m/z 183 (M+-I7) and m/z 155 (M+-45) with a weak molecular ion peak at m/z 200. The ~ H NM R spectrum 200 MHz (CDC13) showed a triplet at 6 0.9 (3...

Obveznopravni odnosi u prijevozu živih životinja morem

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Ivo Grabovac

2006-08-01

Full Text Available Prijevoz živih životinja morem spada u tzv. posebne prijevoze. Žive životinje su tijekom prijevoza izložene posebnim, samo njima kao živim bićima svojstvenim rizicima. Mjerodavne međunarodne konvencije i domaći propisi imaju neka posebna rješenja u prijevozu ove vrste robe, kojima je zapravo svrha omogućiti pogodniji pravni položaj prijevoznika. Autor u ovom radu ističe određene osobitosti u sadržaju prava i obveza ugovaratelja iz prijevoza živih životinja morem, a na temelju međunarodnih konvencija i nacionalnih propisa, osobito Pomorskog zakonika Republike Hrvatske.

Prague quadrennial 14.06-20.06/2007. Short play: crisis of forties flood after rain/ Vladimir Anshon

Index Scriptorium Estoniae

Anšon, Vladimir, 1963-

2010-01-01

XI rahvusvahelisest Praha lavastuskunstnike kvadriennaalist (Prague Quadrennial). Eesti rahvuslikust väljapanekust, kuraator Ene-Liis Semper ja Eesti Kunstiakadeemia väljapanekust, kuraator Lilja Blumenfeld

Agenda kultuuripealinna ArtGendast / Reet Varblane

Index Scriptorium Estoniae

Varblane, Reet, 1952-

1998-01-01

24. maini Stockholmi Kulturhusetis avatud Balti mere maade noortebiennaalist 'ArtGenda'. Peakorraldaja Beate Sydhoff. Eestlaste - Ene-Liis Semper, Martin Pedanik, Andrus Kõresaar, Marko Laimre - esinemisest.

Metabolism of 19-methyl-substituted steroids by human placental aromatase

International Nuclear Information System (INIS)

Beusen, D.D.; Carrell, H.L.; Covey, D.F.

1987-01-01

The 19-methyl analogues of androstenedione and its aromatization intermediates (19-hydroxyandrostenedione and 19-oxoandrostenedione) were evaluated as substrates of microsomal aromatase in order to determine the effect of a 19-alkyl substituent on the enzyme's regiospecificity. Neither the androstenedione analog [10-ethylestr-4-ene-3,17-dione (1c) nor the 19-oxoandrostenedione analog [10-acetylestr-4-ene-3,17-dione (3c)] was converted to estrogens or oxygenated metabolites by placental microsomes. In contrast, both analogues of 19-hydroxyandrostenedione [10-[(1S)-1-hydroxyethyl] extr-4-ene-3,17-dione (2c) and 10-[(1R)-1-hydroxyethyl]estr-4-ene-3,17-dione (2e)] were converted to the intermediate analog 3c in a process requiring O 2 and either NADH or NADPH. No change in enzyme regiospecificity was detected. The absolute configuration of 2e was determined by X-ray crystallography. Experiments with 18 O 2 established that 3c generated from 2c retained little 18 O ( 18 O (≅ 70%). All four 19-methyl steroids elicited type I difference spectra from placental microsomes in addition to acting as competitive inhibitors of aromatase. Pretreatment of microsomes with 4-hydroxyandrostenedione (a suicide inactivator of aromatase) abolished the metabolism of 2c and 2e to 3c, as well as the type I difference spectrum elicited by 2c and 2e. The failure of 2c, 2e, and 3c to undergo aromatization was rationalized in the context of a mechanistic proposal for the third oxygenation of aromatase requiring hydrogen abstraction at C 1 of 19,19-dihydroxyandrostenedione, homolytic cleavage of the C 10 -C 19 bond, and oxygen rebound at C 19

Aportaciones al conocimiento de la compresión tardía en la Cordillera Ibérica centro-oriental: la cuenca neógena inferior del Mijares (Teruel-Castellón

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Paricio Cardona, J.

1986-10-01

Full Text Available The lower Neogene deposits of the Mijares valley (mainly fluvial facies are filling three paralell• grabens controlled by synsedimentary ENE normal faults. This structural pattern is created during a moderate compression phase with an ENE horizontal σ₁ axis which sometimes can be permuted with the vertical σ₂. Afterwards. a second SSE to S compression affects these deposits. The age of the basin can be established in the Upper Aragonian-Lower Vallesian bested on the Micromamal fauna found in two localities. Other sites in the cetral-oriental lberian Chain also show compressive deformations in well-dated deposits of Agenian and Aragonian ages. The compression still continues in this region during the Lower and Middle Miocene, the passage to the extension regime talking place in the Vanesian.

Las facies esencialmente fluviales que integran la unidad interior~ del valle medio del Mijares se depositan en tres grabens paralelos controlados por fallas sinsedimentarias ENE de componente normal. Este dispositivo estructural se crea en el curso de una etapa. compresiva de intensidad moderada, con un σ₁ según ENE, que eventualmente se intercambia con σ₂ vertical. Una segunda etapa de compresión SSE a S afecta posteriormente a esta unidad, datada en el Astaranciense-Vallesiense gracias a la fauna de micromamíferos proporcionada por dos yacimientos. Otras localidades de la Cadena Ibérica centro-oriental registran asimismo deformaciones compresivas en depósitos bien datados entre el Ageniense y el Aragoniense. Aunque sin producir apenas pliegues, el régimen compresivo perdura aún claramente en este sector de la cadena durante toda la primera mitad del Mioceno, siendo en el Vallesiense cuando se produce el tránsito definitivo a la distensión.

Jan Gehli teose "Linnad inimestele" ilmumine = Publication of an Estonian-language Edition of Jan Gehl's Cities for People / Yoko Alender, Liina Teder, Neeme Lopp

Index Scriptorium Estoniae

Alender, Yoko, 1979-

2016-01-01

Taani arhitektist Jan Gehlist ja tema raamatust "Linnad inimestele". Eestikeelse väljaande toimkond: Yoko Alender, Neeme Lopp, Liina Teder, Eneli Rohtla. Maastikuarhitektuuri aastapreemia nominent 2016

GORLİN - GOLTZ SENDROMU OLGU BİLDİRİSİ-GORLIN-GOLTZ SYNDROME (CASE REPORT)

OpenAIRE

Timoçin, Necla; Doğan, Özen

2013-01-01

ÖZETGorlin-Goltz sendromu, multipl çene kistleri, bazal hücreli tıevus, bazal hücreli karsînom, iskeletsel anomaliler ve bazı yumuşak doku lezyonlan ile karakterize bir hastalıktır. Sendromun bugüne kadar 40'a yakın bulguları bildirilmiştir. Bu makalede multipl çene kistleri ve tipik yüz görünümlerinden yola çıkılarak incelemeye alınıp,sendroma ait bazı iskeletsel anomalilerin saptanması üzerine Gor-Hn-Goltz Sendromu tanısı konan iki olgu bildirilmektedir.Anahtar sözcükler : Gorlin-Goltz...