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Sample records for hedrick miriam martinez

  1. Presidential Green Chemistry Challenge: 2012 Academic Award (Waymouth and Hedrick)

    Science.gov (United States)

    Presidential Green Chemistry Challenge 2012 award winners, Professor Robert M. Waymouth and Dr. James L. Hedrick, developed a broad class of highly active, environmentally benign, metal-free catalysts for synthesizing plastics.

  2. Entrevista: Joan Martinez-Alier

    Directory of Open Access Journals (Sweden)

    Maria Amélia Enríquez

    2011-07-01

    Full Text Available Nesta seção de entrevistas da Revista “Sustentabilidade em Debate” nosso convidado especial é Joan Martinez-Alier, um dos maiores expoentes da economia ecológica. Martínez-Alier é professor aposentado da Universidade Autônoma de Barcelona (UAB, onde ministrou disciplinas de economia e história econômica. Foi pesquisador do Saint Antony’s College, em Oxford, e professor visitante da FLACSO, Equador. Membro fundador, e presidente no período 2006-2007, da Sociedade Internacional de Economia Ecológica (ISEE e da Associação Européia de Economia Ambiental. Também foi membro do comitê científico da Agência Européia do Ambiente. Autor de vários livros, entre os quais se destaca “O Ecologismo dos Pobres” com publicação em vários países, inclusive no Brasil (São Paulo: Contexto, 2007 – 1ª. edição que já está em segunda edição revisada e atualizada. Atualmente, Alier coordena o projeto europeu EJOLT (Environmental Justice Organizations, Liabilities and Trade no ICTA, UAB. A entrevista está estruturada em quatro tópicos: 1 Crise econômica e os novos desafios para a economia; 2Energia e bens primários; 3 Economia Ecológica e 4 Ecologismo dos Pobres

  3. Teaching the Very Recent Past: "Miriam's Vision" and the London Bombings

    Science.gov (United States)

    Kitson, Alison; Thompson, Sarah

    2015-01-01

    "Miriam's Vision" is an educational project developed by the Miriam Hyman Memorial Trust, an organisation set up in memory of Miriam Hyman, one of the 52 victims of the London bombings of 2005. The project has developed a number of subject-based modules, including history, which are provided free to schools through the website…

  4. In memoriam : Miriam Dorothy (Posner) Finkel (1916-1999)

    International Nuclear Information System (INIS)

    Reilly, C.A.

    2000-01-01

    Miriam P. Finkel, pioneer radiobiologist, passed away on August 20, 1999, at her home in Tucson, AZ. She was born on January 22, 1916, in Chicago to Russian immigrants. She spent much of her youth in Davenport, IA. She returned to Chicago for her college education, and received a B.S. in zoology in 1938 from the University of Chicago. While continuing her formal education in zoology, Miriam served as a laboratory instructor at Wilson Junior College. She received her Ph.D. in 1944 from the University of Chicago. She began her scientific career at the dawning of the nuclear age and seized upon the scientific opportunity present in the new field of radiobiology to be a life-long contributor to the understanding of the biological effects of radiation. Her technical insights and discoveries helped form the foundation for many of the health standards (i.e. permissible levels of internal radionuclide exposure) in use today. She also made a significant contribution to the field of molecular biology. Her isolation of a murine osteogenic sarcoma virus, the Finkel-Biskis-Jenkins or FBJ virus, led to fundamental discoveries in viral-induced tumors and ultimately provided the now universally used molecular biological tool, the FOS gene.

  5. The case of Mr. Martinez: ethical conflicts in home care.

    Science.gov (United States)

    Green, M V

    1997-06-01

    Mr. Martinez recently was accepted into the Valley Hospice Program with a diagnosis of end-stage lung cancer. He currently lives with his daughter, Amelia, after moving from Puerto Rico 2 years ago after his wife died. His two sons and another daughter live within 20 minutes of Amelia's home. They are a close-knit family, and the children are committed to honoring Martinez' wishes to die in his room in Amelia's home.

  6. “Draw yourself out of it” : Miriam Katin’s graphic metamorphosis of trauma

    NARCIS (Netherlands)

    Oostdijk, Diederik

    2018-01-01

    Miriam Katin's two graphic memoirs We Are on Our Own [(2006). Montreal: Drawn & Quarterly] and Letting It Go [(2013). Montreal: Drawn & Quarterly] both reflect on how the trauma of the Holocaust can be transformed through and in art. In the former Katin details how she and her mother narrowly escape

  7. “Draw yourself out of it”: : Miriam Katin’s Graphic Metamorphosis of Trauma

    NARCIS (Netherlands)

    Oostdijk, D.M.

    2018-01-01

    Miriam Katin's two graphic memoirs We Are on Our Own [(2006). Montreal: Drawn & Quarterly] and Letting It Go [(2013). Montreal: Drawn & Quarterly] both reflect on how the trauma of the Holocaust can be transformed through and in art. In the former Katin details how she and her mother narrowly escape

  8. 78 FR 12050 - S. Martinez Livestock, Inc.; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2013-02-21

    ... Livestock, Inc.; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments.... Martinez Livestock, Inc. filed an application for a preliminary permit, pursuant to section 4(f) of the... megawatt hours. Applicant Contact: Mr. Daniel T. Martinez, S. Martinez Livestock, Inc., 13395 Hwy. 24...

  9. Gender Equality and Women Empowerment Gleaned in the Selected Speeches of Senator Miriam Defensor Santiago

    Directory of Open Access Journals (Sweden)

    Maria Luisa A. Valdez

    2017-02-01

    Full Text Available Gender inequality and the resulting discrimination of women are deeply rooted in history, culture and tradition. It is said to be detrimental to the mental health of women and persists as a debilitating stigma which lowers their dignity and sense of self-worth. Thus, this qualitative research was conducted to underscore the issue of gender equality and women empowerment as core topics in selected speeches of Senator Miriam Defensor Santiago. Findings of the analysis showed that the issue of gender gap in the Philippines was manifested and discussed forthrightly by the senator in her speeches in terms of educational attainment, health and survival, economic participation and opportunity, and political empowerment, all being effectively touched by the senator with the signature wit, eloquence, astuteness and passion she was widely known for; that gender equality and women empowerment were likewise gleaned in the selected speeches, all of which were delivered by Miriam Defensor Santiago with the motive of persuading her audience to espouse the same advocacy, and this she achieved through her unique and distinct style of utilizing the persuasive ability of literature; and, that the implications of the author's advocacy on gender equality and gender empowerment delegated the monumental task upon the shoulders of the Filipino youth, in ways that their thinking will be directly influenced by her advocacy and thus promote within them a sense of urgency to embrace and espouse the same advocacies in order for them to be able to contribute to nation building.

  10. The riverbank, the seashore and the wilderness: Miriam, liberation and prophetic witness against empire

    Directory of Open Access Journals (Sweden)

    Allan A. Boesak

    2017-07-01

    Full Text Available This article examines the manner and method of resistance against patriarchal power and privilege. Two types of power are contrasted. One is the violent, war-like and hierarchical power of an empire, and the other is the faithful resistance of Israel’s prophets. A further distinction is made between violent male power and non-violent female power. It is argued that Miriam was a prophet of the people and her prophetic witness is an example of the power and outcome of non-violent resistance. Her theology explicitly and specifically praises God not as a warrior. Hers is not a muscular, masculine God whose power seeks to match the power of empire. Her God has a power that through radical love for a slave people and taking sides with the enslaved overcomes the power of the slaveholder. In her theology, Miriam recalls the God of the exodus, who begins the acts of liberation with the women, to whose faithfulness, courage and defiant obedience, the freedom of the people is entrusted. From a feminist perspective it is argued that this style of non-violent, faithful prophetic witness has a greater impact than violent resistance associated with an empire-like power. It is suggested that black liberation theology should adopt this paradigm in its witness of and resistance against oppression.

  11. Loodusesõber / Maria Martinez Ros ; küsis Marika Makarova

    Index Scriptorium Estoniae

    Martinez Ros, Maria

    2012-01-01

    Intervjuu Tallinnas ja Lilleorus tantsuteraapia kursusi andva mehhiklanna Maria Martinez Rosiga, kes on õppinud permakultuuri disaini, humanistliku psühholoogiat, tanatoloogiat, Feldenkraisi meetodit, tema vaadetest jätkusuutlikule elamise viisile

  12. Triatoma melanosoma, novo status para Triatoma infestans melanosoma Martinez, Olmedo & Carcavallo, 1987 (Hemiptera: Reduviidae Triatoma melanosoma, new status for Triatoma infestans melanosoma Martinez, Olmedo & Carcavallo, 1987 (Hemiptera: Reduviidae

    Directory of Open Access Journals (Sweden)

    Herman Lent

    1994-09-01

    Full Text Available Triatoma infestans melanosoma was described in 1987 by Martinez, Olmedo & Carcavallo. In the present work the authors make a redescription, adding new characters, and based on biological and morphological aspects raise up to the level of species and being identified as Triatoma melanosoma. A detailed morphological study of the external male genitalia was made.

  13. Application of modified Martinez-Silva algorithm in determination of net cover

    Science.gov (United States)

    Stefanowicz, Łukasz; Grobelna, Iwona

    2016-12-01

    In the article we present the idea of modifications of Martinez-Silva algorithm, which allows for determination of place invariants (p-invariants) of Petri net. Their generation time is important in the parallel decomposition of discrete systems described by Petri nets. Decomposition process is essential from the point of view of discrete system design, as it allows for separation of smaller sequential parts. The proposed modifications of Martinez-Silva method concern the net cover by p-invariants and are focused on two important issues: cyclic reduction of invariant matrix and cyclic checking of net cover.

  14. "Spillover of interpersonal conflicts from work into nonwork: a daily diary study": correction to Martinez-Corts et al.

    NARCIS (Netherlands)

    Martinez-Corts, I.; Demerouti, E.; Bakker, A.B.; Boz, M.

    2015-01-01

    Reports an error in "Spillover of Interpersonal Conflicts From Work into Nonwork: A Daily Diary Study" by Inés Martinez-Corts, Evangelia Demerouti, Arnold B. Bakker and Marina Boz (Journal of Occupational Health Psychology, Advanced Online Publication, Jan 19, 2015, np). There was a misspelling in

  15. 78 FR 37792 - Mario Julian Martinez-Bernache, Inmate Number #95749-279, CI Big Spring, Corrections Institution...

    Science.gov (United States)

    2013-06-24

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security Mario Julian Martinez-Bernache, Inmate... Order with the Under Secretary of Commerce for Industry and Security. The appeal must be filed within 45... the Internal Security Act of 1950 (50 U.S.C. 783(b)), or section 38 of the Arms Export Control Act (22...

  16. Caught in a Web of Abjection: High-Stakes Testing in Miriam Cohen's "First Grade Takes a Test" and Andrew Clements' "The Report Card"

    Science.gov (United States)

    Anderson, Anne W.

    2018-01-01

    Standardized achievement testing of children began in the United States in the 1960s. Since then, the data produced from such tests has been extrapolated to measure schools, teachers, and principals. Today, testing and its corollaries consume much of the time and energy of teachers and students. Miriam Cohen's (2006/1980) "First Grade Takes a…

  17. Antibacterial and antioxidant activity of Portuguese Lavandula luisieri (Rozeira) Rivas-Martinez and its relation with their chemical composition.

    Science.gov (United States)

    Pombal, Sofia; Rodrigues, Cleide F; Araújo, João P; Rocha, Pedro M; Rodilla, Jesus M; Diez, David; Granja, Ángela P; Gomes, Arlindo C; Silva, Lúcia A

    2016-01-01

    Lavandula luisieri (Rozeira) Rivas-Martinez is an endemic aromatic Labiatae the Iberian Peninsula, common in semi-arid regions of southern Portugal and southwestern Spain, that produces an active antibacterial essential oil from the leaves and flowers. This work presents the study of the chemical variation in various stages of growth of leaves and flowers of L. luisieri. It has been found that the essential oils are mainly constituted by 1,8-cineol, camphor, linalool and trans-α-necrodil acetate. It was also studied the total phenol content and the antioxidant activity on leaves and flowers. The ethanol extraction from de leaves contents the highest total phenol, important factor for the antioxidant activity of the plant, extract. It has been studied too, the antibacterial activity against Escherichia coli, Salmonella spp . and Staphylococcus aureus . In accordance with the obtained results, the antibacterial activities stand out against Staphylococcus , of the oil of L. luisieri (leaves and flowers).

  18. Prefácio - De agonismos e antagonismos: para uma ética-política do dissenso - por Horacio Luján Martinez

    Directory of Open Access Journals (Sweden)

    REA Editor

    2010-10-01

    Full Text Available

    Prefácio de: MARTINEZ, Horácio Luján. Poder e Política: horizontes de antagonismos. Curitiba: Editora CRV, 2010, 170p.

  19. Aesthetics of amalgamation / Francisco Martinez

    Index Scriptorium Estoniae

    Martínez, Francisco, 1982-

    2016-01-01

    Parandamise esteetika kontseptsioonist näituste „Ehitamata. Visioonid uuest ühiskonnast 1986–1994“ Eesti Arhitektuurimuuseumis (kuraator Ingrid Ruudi) ja “Parandamise esteetika tänapäeva Gruusias” (kuraator Marika Agu) Tartu Kunstimuuseum valgusel

  20. Primazia do real na construção do conhecimento científico e primazia da teorização na construção de pesquisas científicas: contribuições metodológicas a partir de Miriam Limoeiro Cardoso

    Directory of Open Access Journals (Sweden)

    Siomara Moreira Vieira Borba

    2015-06-01

    Full Text Available http://dx.doi.org/10.5007/2175-795X.2015v33n1p429 Neste artigo, reivindica-se a possibilidade de desenvolvimento de pesquisas educacionais tendo por referência a contribuição metodológica de Miriam Limoeiro Cardoso, posição que envolve dois movimentos desta pesquisa. Inicialmente, são expostas as teses da distinção entre realidade e objeto científico e da teorização como processo inicial da construção do objeto de investigação, que sintetizam o exame que autora empreende a partir dos apontamentos metodológicos de Karl Marx em seu processo de elaboração de uma teoria geral do capitalismo. A possibilidade da fecundidade de suas contribuições resulta da constatação de problemas na relação entre teoria e empiria que é identificada através da sumarização de análises da pesquisa educacional brasileira até início deste século, possivelmente ainda atual.   Real primacy in the construction of scientific knowledge and the primacy of theory in the construction of scientific research: methodological contributions from Miriam Limoeiro Cardoso  Abstract In this article it is claimed the possibility of developing educational research bearing in mind Miriam Limon Cardoso´s reference to the methodological contribution , a position that involves two research movements. At first, it is exhibited the thesis of the distinction between reality and scientific object and of the theorization as the initial process of the research object construction, which synthesize the examination which the author undertake from Karl Marx´s methodological notes in his process of elaboration of a general capitalism theory. The possibility of fecundity of her contributions result from the verification of problems between theory and practice that is identified by summarizing  the analysis of the Brazilian educational research up to the beginning of this century, which is still current. Keywords: Scientific knowledge. Miriam Limoeiro Cardoso

  1. 21 October 2008 - LHC Inauguration - Spanish State Secretary for Research C. Martinez welcomed by CERN Director-General R. Aymar, CERN Chief Scientific Officer J. Engelen and CERN Financial Officer S. Lettow and signing the electronic guest book with theoretical physicist A. de Rújula.

    CERN Multimedia

    LHC 2008

    2008-01-01

    21 October 2008 - LHC Inauguration - Spanish State Secretary for Research C. Martinez welcomed by CERN Director-General R. Aymar, CERN Chief Scientific Officer J. Engelen and CERN Financial Officer S. Lettow and signing the electronic guest book with theoretical physicist A. de Rújula.

  2. Potabilidad del agua en Acueductos de San Juan y Martínez Provincia Pinar del Río. 2009- 2010 Water potability in San Juan y Martinez aqueducts. Pinar del Rio province. 2009-2010

    Directory of Open Access Journals (Sweden)

    Jesús Hernández García

    2012-06-01

    Full Text Available Se realizó una investigación longitudinal-descriptiva y prospectiva en los acueductos "Hoyo de Mena y Hermanos Saíz" de San Juan y Martínez en el período comprendido de enero de 2009 a diciembre de 2010, donde se caracterizó la calidad del agua a través de exámenes de laboratorio en las redes de distribución. El objetivo de esta investigación estuvo dirigido a evaluar la calidad sanitaria del agua suministrada por ambos sistemas en los Consejos Populares estudiados a través de exámenes bacteriológicos y físico químico. Quedó demostrado en la investigación realizada la mala calidad del agua suministrada por los acueductos "Hoyo de Mena con el 81% y Hermanos Saíz" , con un 78% de potabilidad respectivamente durante el año 2009, por la inestabilidad en el suministro de hipoclorito de sodio y roturas de los equipos de cloración, siendo más significativo en "Hermanos Saíz" por las deficiencias descritas con anterioridad durante el año 2010; se reportó el 81,9% de potabilidad y el 90.6 % en el Consejo Popular Urbano y evaluó el agua suministrada por estos sistemas de mala calidad en este período. Con todos los resultados obtenidos en el período analizado fueron confeccionadas tablas; se realizó el cálculo estadístico de X², con un nivel del significación del 95 %.A longitudinal-descriptive, prospective research was conducted at “Hoyo de Mena and Hermanos Saiz” aqueducts in San Juan y Martinez during January 2009 to December 2010, where the quality of water was characterized following laboratory examinations in water-supply networks. By means of this research the hygienic quality of water was assessed through bacterial and physical-chemical examinations; which water is supplied by both systems in the Popular Councils under studies. The quality of water supplied by “Hoyo de Mena (81% and Hermanos Saiz (78%” presented a poor quality during 2009 respectively, due to the unstable availability of chlorine and ruptures

  3. Conocimientos del virus de inmunodeficiencia humana en estudiantes del preuniversitario de San Juan y Martínez Knowledge of Human Immunodeficiency Virus in pre-university students. San Juan y Martinez municipality

    Directory of Open Access Journals (Sweden)

    Geisell Martínez Torres

    2012-10-01

    Full Text Available Introducción: el virus de la inmunodeficiencia humana es el causante del sida, debilita el sistema inmunológico destruyéndolo lentamente y ataca a las células que actúan como coordinadores del sistema inmunológico, provocando una respuesta de defensa inmunológica. Objetivo: determinar el nivel de conocimientos de los adolescentes que estudian en el preuniversitario acerca del Virus de la Inmunodeficiencia Humana. Material y método: se realizó una investigación de tipo observacional, descriptiva, transversal en el área urbana del municipio San Juan y Martínez en el período comprendido de enero hasta mayo de 2012, a los adolescentes que estudian en el preuniversitario. Resultados: se comprobó que existe un predominio del sexo femenino que conoce que el VIH/sida es una infección de transmisión sexual, señalan al semen como la vía que más conocen por la cual se transmite el VIH/sida, y la abstinencia sexual como la más efectiva para evitar el contagio; no usan el condón siempre en las relaciones sexuales, y la mayoría se dirige a sus padres para conversar sobre temas de sexualidad y VIH/sida. Conclusiones: la mayor parte de los estudiantes refiere conocer que el VIH/sida es una enfermedad que se transmite sexualmente, y que es necesario ejecutar programas de educación sexual para adquirir mejores conocimientos sobre esta enfermedad venérea.Introduction: Human Immunodeficiency Virus (HIV causes Acquired Immunodeficiency Syndrome (AIDS and weakens the immune system destroying it progressively and attacking cells that act of coordinators of the immunological system, provoking a response of the immunological defence. Objective: to determine knowledge of Human Immunodeficiency Virus in adolescents studying in an urban pre-university institute. Material and Method: a type of observational, descriptive, cross-sectional research was conducted in an urban area of San Juan y Martinez municipality during January-May 2012 in adolescents

  4. Kunstitudeng müügiks / Miriam Dagan

    Index Scriptorium Estoniae

    Dagan, Miriam

    2006-01-01

    Saksamaa näitel eri riikides ilmneva tendentsi üle, kus üliõpilased hakkavad juba õpingute ajal galeriide kaudu oma loomingut müüma. Neo Rauchi, Daniel Richteri õpilastest. Galerist Sebastian Klemmi seisukohtadest

  5. The riverbank, the seashore and the wilderness: Miriam, liberation ...

    African Journals Online (AJOL)

    2017-07-25

    Jul 25, 2017 ... feminist perspective it is argued that this style of non-violent, faithful prophetic witness has a ..... now shared by Yahweh and the military leader, the king. For the first ...... increasingly autocratic, and increasingly unpopular, rule.

  6. 75 FR 33170 - Safety Zone; City of Martinez 4th of July Fireworks, Martinez, CA

    Science.gov (United States)

    2010-06-11

    ... is meant for entertainment purposes and will be used to celebrate Independence Day. The fireworks... under Executive Order 13211. Technical Standards The National Technology Transfer and Advancement Act... involves establishing, disestablishing, or changing Regulated Navigation Areas and security or safety zones...

  7. 76 FR 37653 - Safety Zone; Independence Day Fireworks Celebration for the City of Martinez, Martinez, CA

    Science.gov (United States)

    2011-06-28

    ... display is meant for entertainment purposes. This safety zone establishes a temporary restricted area on... of Energy Effects under Executive Order 13211. Technical Standards The National Technology Transfer.... This rule involves establishing, disestablishing, or changing Regulated Navigation Areas and security...

  8. 76 FR 61712 - Deborah Martinez Seldon: Debarment Order

    Science.gov (United States)

    2011-10-05

    ... special termination of debarment to the Division of Dockets Management (HFA-305), Food and Drug...-toxin to be returned to the FDA, seeking to create the misleading impression that they were returning 28..., creating the false impression that the office was using approved BOTOX when, in fact, patients were being...

  9. 78 FR 38833 - Safety Zone: City of Martinez Fourth of July Fireworks Display, Carquinez Strait, Martinez, CA

    Science.gov (United States)

    2013-06-28

    ... submitting material to the docket, call Program Manager, Docket Operations, telephone (202) 366-9826... (NAD 83) as depicted in National Oceanic and Atmospheric Administration (NOAA) Chart 18657. Upon the... restricted area around the launch site is necessary to protect spectators, vessels, and other property from...

  10. Aspectos clínico-epidemiológicos de la cardiopatía isquémica en San Juan y Martínez, 2009 Clinical and epidemiological aspects of ischemic heart disease in San Juan y Martinez, 2009

    Directory of Open Access Journals (Sweden)

    Guillermo Luís Herrera Miranda

    2010-03-01

    Full Text Available La cardiopatía isquémica es un problema de salud que cobra un gran número de vidas y es la causa de invalidez en la población mundial. Con el objetivo de identificar los aspectos clínicos epidemiológicos que caracterizan a la cardiopatía isquémica en 150 pacientes de 15 años y más, pertenecientes a tres consultorios médicos del Consejo Popular "Galope, San Juan y Martínez", en el periodo comprendido enero _ julio del año 2009, y por ser este el de mayor incidencia y prevalencia en el municipio se realizó una investigación descriptiva y transversal, que incluyó el interrogatorio, examen físico y electrocardiograma a la totalidad de la muestra, procesándose los datos a través del valor porcentual y Ji cuadrado en los casos necesarios. Se encontró un mayor número de hombres que mujeres en la muestra estudiada. En ambos grupos predominaron las edades superiores a 56 años. La cardiopatía isquémica sin angina fue la forma clínica que prevaleció, mientras que las alteraciones del segmento S-T predominaron entre los hallazgos electrocardiográficos. El hábito de fumar, el sedentarismo y la hipertensión arterial fueron los factores de riesgo más frecuentes en la serie. Los mismos se incrementaron a medida que aumento la edad, y todos predominaron de manera significativa en el grupo con cardiopatía isquémica. Se encontró una relación directamente proporcional entre los factores de riesgo asociados entre sí y la cardiopatía isquémica.Ischemic Heart Disease is a health problem that takes a great number of lives off and it is a cause of disability all over the world. The objective of this research was to identify clinical and epidemiological aspects that characterize ischemic heart disease in 150 patients (15 years or older, belonging to three doctor's offices in the Popular Council of "Galope", San Juan y Martinez, Pinar del Rio during January-July 2009. This place presents the greatest incidence and prevalence in the

  11. A green management framework for hotels : a case of two African countries / Miriam Mbasera

    OpenAIRE

    Mbasera, Miriam

    2015-01-01

    Currently, there are environmental issues the world is facing which include global climate change, ozone depletion, pollution, high consumption of resources and increasing amounts of solid waste. Tourism is one of the largest industries and it is an important economic tool. However, it also has many negative effects on the environment. Hotels as one of the tourism industry’s component parts have a significant impact on the environment. From an environmental perspective, hotels consume a large...

  12. Barbarid, plastiliinijänes, Miriam ja Frank Muller / Annika Koppel

    Index Scriptorium Estoniae

    Koppel, Annika

    2003-01-01

    Nukufilm näitab 4 uut filmi : "Barbarid" (stsenaristid Andrus Kivirähk ja Hardi Volmer, režissöör H. Volmer), "Porgand" (stsenarist Peep Pedmanson, režissöör Pärtel Tall), "Miriami jõulupäkapikk" (stsenaristid Leelo Tungal ja Peep Pedmanson, režissöör Mait Laas), "Kuuvaatleja" (reklaamitreiler Frank Mulleri kellafirmale ; stsenarist, režissöör, kunstnik Mati Kütt)

  13. Acting without seeing: Eye movements reveal visual processing without awareness Miriam Spering & Marisa Carrasco

    OpenAIRE

    Spering, Miriam; Carrasco, Marisa

    2015-01-01

    Visual perception and eye movements are considered to be tightly linked. Diverse fields, ranging from developmental psychology to computer science, utilize eye tracking to measure visual perception. However, this prevailing view has been challenged by recent behavioral studies. We review converging evidence revealing dissociations between the contents of perceptual awareness and different types of eye movements. Such dissociations reveal situations in which eye movements are sensitive to part...

  14. Acting without seeing: Eye movements reveal visual processing without awareness Miriam Spering & Marisa Carrasco

    Science.gov (United States)

    Spering, Miriam; Carrasco, Marisa

    2015-01-01

    Visual perception and eye movements are considered to be tightly linked. Diverse fields, ranging from developmental psychology to computer science, utilize eye tracking to measure visual perception. However, this prevailing view has been challenged by recent behavioral studies. We review converging evidence revealing dissociations between the contents of perceptual awareness and different types of eye movements. Such dissociations reveal situations in which eye movements are sensitive to particular visual features that fail to modulate perceptual reports. We also discuss neurophysiological, neuroimaging and clinical studies supporting the role of subcortical pathways for visual processing without awareness. Our review links awareness to perceptual-eye movement dissociations and furthers our understanding of the brain pathways underlying vision and movement with and without awareness. PMID:25765322

  15. Priscilla Martinez1, Anne landheim2, thomas clausen1, & lars lien3 ...

    African Journals Online (AJOL)

    Alcohol use is an important part of the health profile of older adults, and little is ... and adult health (SAGE) conducted in Ghana and South Africa. ..... Indian/Asian ..... an overall hazardous consumption culture, and .... Ageing & Mental Health11.

  16. Martinez-Romero et al., Afr J Tradit Complement Altern Med. (2016 ...

    African Journals Online (AJOL)

    acer

    198 ... Conclusion: It was possible to know and discuss the variety of applications of the Neem tree, including the bark, leaves, fruit, flowers, and roots, each with very favorable ... antifungal, dermatological, and dental agent. This oil has been ...

  17. Homenaje a Hernando Martinez Rueda y su "Memorial a la Academia"

    Directory of Open Access Journals (Sweden)

    Fernando Serpa Florez

    1994-12-01

    Full Text Available

    Hernando Martínez Rueda fue un médico que sobresalió por su extraordinario talento. Hijo del doctor Pompilio Martínez ex-presidente de la Academia (1926-1928, primo hermano de otro ex presidente de nuestra corporación, el doctor Guillermo Rueda Montaña (1975-1977, padre de Gonzalo Martínez Sanmartín también médico y cuñado de los Académicos Humberto Rosselli y Carlos Sanmartín Barberi, unió su carrera con la que brilló por su dominio científico, a diferentes actividades humanísticas, como la docencia, en el Departamento de Ciencias de la Universidad de los Andes, la lingüística (hablaba numerosos idiomas y su biógrafo, Abelardo Forero Benavides recuerda que, en seis meses, aprendió el ruso y el árabe. Intervino en política, circunstancialmente, como suplente en el Senado de Laureano Gómez.

    Como escritor publicó ingeniosas poesías “A la manera de…”, en buena hora editadas en un volumen que lleva ese título, por el Banco de la República, en 1980.

    El Académico Efraím Otero Ruiz, también Ex- Presidente (1990-1992 le dedicó sus “sonetos jocosos” -que próximamente serán publicados en forma de libro–. El soneto se originó en el regalo que le hiciera el Académico Roselli Quijano del libro publicado por el Banco de la República y en algunos documentos y narraciones que sobre el nunca bien lamentado Martínez Rueda (o “Martinón”, como le decían sus allegados más cercanos le fueron dados por el Académico Sanmartín. Dice el soneto:

    Martinón: si te hubiese conocido
    vivo el brillo lustral de tus magines,
    rodeado de Rosellis, Sanmartines,
    y todo lo notable que ha vivido,

    cuánto hubiera gozado haberte oído
    despotricar de tántos malandrines,
    menguarle al dictador sus espolines
    y hasta a Gaitán su pródiga libido …

    Pero te oí ya precozmente muerto.
    Tu colección la recibí de Humberto
    y el elogio final tal vez de Carlos …

    y me quedé pensando, como muchos,
    que bardos como tú serán tan duchos,
    que tardarán un siglo en imitarlos!

    La revista MEDICINA, órgano de la Academia Nacional de Medicina, como homenaje a Hernando Martínez Rueda, gran señor de la pluma, de la medicina y del talento, publica hoy su “Memorial a la Academia”, con cordial afecto.

    F.S.F.

    Señores de la Médica Academia:
    Ya que la tierra nuestra, por fortuna,
    Libre está de la plaga y de la endemia
    Me parece oportuna
    La discusión de puntos que os someto,
    Sobra decir, con el mayor respeto.

    Para empezar, quisiera
    Que se analice a fondo y se debata
    Si verdaderamente era de plata
    El maxilar del General Mosquera.

    Si hay razones de peso
    Para que afirmen que don Bias de Lezo
    En Cartagena derrotó al pirata
    Con sólo un ojo, un brazo y una pata.

    Y averiguar muy útil considero
    Si es cierto o si es de antojo
    Que Cervantes fue manco, ciego Homero,
    Ovidio narigudo y Byron cojo.

    Si la fuente Juvencia
    Que Ponce de León buscó en Florida
    En verdad existió, según la ciencia;
    O si es, como se teme,
    El agua mineral tan conocida
    Preparada por Walter Carroll M.

    Si es cosa averiguada
    Que pudo ser origen de oftalmías
    Aquella golondrina poco aseada
    Que voló sobre el padre de Tobías.

    Si lo de la ballena con Jonás
    Fue Verdad o fue mito
    Y de cuáles disp(!psias, además
    Sufrió después el pobre animalito.

    Que PI señor Secretario
    Pregunte en una próxima sesión
    Si un centauro atacado de torzón
    Llama al galeno o al veterinario.

    En sabias discusiones
    Ilustraréis sin duda estas cuestiones
    Para provecho y gloria
    Nuestra, de la Academia y de la Historia.

  18. Management of Antithrombotic Agents in Oral Surgery Maria Martinez and Dimitrios A. Tsakiris *

    Directory of Open Access Journals (Sweden)

    Maria Martinez

    2015-10-01

    Full Text Available Systemic anticoagulation with intravenous or oral anticoagulants and antiplatelet agents is an efficient treatment against thromboembolic or cardiovascular disease. Invasive dental procedures or oral surgery might be associated with bleeding complications if carried out under anticoagulants. Patients on vitamin K antagonists, new direct anticoagulants or antiplatelet agents having dental interventions with low-risk for bleeding do not need interruption of anticoagulation. In case of bleeding complications local hemostatic measures, such as local surgical sutures, fibrin glue, local antifibrinolytic treatment with tranexamic acid, or e-aminocaproic acid suffice to stop bleeding. In patients with high risk of bleeding an individual assessment of the benefit/risk ratio of interrupting anticoagulation should be carried out. Bridging the long-term anticoagulation with short-term anticoagulants should be planned according to national or international guidelines. The introduction of the newer direct oral anticoagulants having more flexible pharmacokinetic properties has facilitated bridging, allowing short-term interruption without increasing the risk of relapsing thrombotic or cardiovascular events.

  19. "Cremaster' tsükkel" : Matthew Barney avastusretk kunsti ja filmikunsti vahealal / Miriam Dagan ; tõlk. Epp Aareleid

    Index Scriptorium Estoniae

    Dagan, Miriam

    2007-01-01

    Ameerika kunstniku ja režissööri kunstnikufilmidest "Cremaster' tsükkel" (1994-2002). Viie tsükli põhisündmusest. Viienda filmi rekvisiitor oli Meeli Salumäe, Kostabi Maailma assistent New Yorgis

  20. Ravijärjekorrad hämmastasid prantsuse arste / Fabien Puglierini, Christian Meriau, Alicia Martinez ; interv. Sigrid Laev

    Index Scriptorium Estoniae

    Puglierini, Fabien

    2004-01-01

    Eestit külastanud prantsuse ja hispaania arstide muljeid Eesti tervishoiusüsteemist. Sarnase probleemina toodi esile personali puudus, kuid ravijärjekordi on Prantsusmaal vaatamata sellele õnnestunud vältida

  1. Alpha List of Prime Contract Awards. Oct 92-Sep 93. FY93. (Leventhal Bros & Co. Inc. - Martinez A M Construction)

    Science.gov (United States)

    1994-03-01

    70I )I() acca I)(T)1(a0ma (00 0(0m( a)0(0(0(In(T)0)(47)(In0In0a) II I(ON I (nl gn (n (fl I(O 1c 00 00 0c4 i,- . . 0A111 IC0ON II 0 0. Oif l ( N I zo c...M ~ 0if 3:n~ a -Qn~D ODn -4(0r -4~O VDDO UtOMýDCJýfa)nOOOY (4) 1 coo M 000 V) o . 11 W 1 33( 00 t’. II - 4- -- 4 - 4- 44 J4 (IL) I too M 11 Li. 11 f6 ...II.0n C MN ýc NID n c- CV)0 CL -4 4 - N CN N% -4 -. CJ C4-4N en~ to f6 - .- If c 40 0 01. N7 1101 r-ICO00 (n 4 a 110100to I coo 00 Co: E rN . 1

  2. 78 FR 37791 - In the Matter of: Jose Guadalupe Reyes-Martinez, Inmate Number #85993-279, CI Adams County...

    Science.gov (United States)

    2013-06-24

    ... DEPARTMENT OF COMMERCE Bureau of Industry and Security In the Matter of: Jose Guadalupe Reyes... the Internal Security Act of 1950 (50 U.S.C. 783(b)), or section 38 of the Arms Export Control Act (22... 750.8 of the Regulations states that the Bureau of Industry and Security's Office of Exporter Services...

  3. The Flipped Classroom: Teaching the Basic Science Process Skills to High-Performing 2nd Grade Students of Miriam College Lower School

    Directory of Open Access Journals (Sweden)

    Mark Kenneth Camiling

    2017-08-01

    Full Text Available Technology has greatly shaped pedagogical practices over time. However scholars posit that the developing technology-aided, -based, and -oriented instructional practices still need scholarly and systematic studies to prove their effectiveness. An emerging teaching strategy that highlights technology tools and programs is Flipped Learning: a strategy where technology redirects learning from large groups to individuals. The research described here hypothesizes that there is a significant difference between the basic science process skills test score means of elementary students in a Flipped classroom and those in a traditional classroom. To test this hypothesis, an experimental design was used as the participants were divided the into two groups: experimental and control. An instructional design was crafted to simultaneously teach both control and experimental groups within a one (1 hour schedule. The experimental group was asked to watch at home researcher-made videos that teach the basic science process skills. In class, these participants deepened understanding of the skills through varied activities. The control group was taught using the traditional method operationalized as 5E Inquiry-Based Model.Both pre- and post-tests were administered to check the relative test scores. A Mann Whitney U test was conducted to evaluate the difference between the basic process skills test mean scores. It is concluded that there is a statistically significant difference (at α=0.05, r = 0.42 with a large effect size between the two variables.

  4. Carlos Martinez-Riera, general-director of international co-operation and institutional relations, ministry of science and innovation for Spain

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    Visited the CMS control room with Maria Chamizo-Llatas, CMS deputy run co-ordinator, CIEMAT, when he came to CERN on 11 May. He also saw the CMS underground experimental area and the LHC superconducting magnet test hall.

  5. Clarín years against Videla and Martinez de Hoz (1976- 1981). Between the political and economic objection

    OpenAIRE

    Borrelli, Marcelo Hernán

    2012-01-01

    En este artículo proponemos una revisión de las principales posiciones editoriales del matutino Clarín frente al proyecto refundacional de la dictadura militar en la etapa 1976-1981, atravesada por los efectos del terrorismo de Estado, las medidas de apertura económica y de valorización financiera implementadas por la conducción económica y el intento desde las Fuerzas Armadas de plasmar un plan político que asegurara a largo plazo las transformaciones materiales e institucionales en curso. P...

  6. Reference: 352 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available |Holtkamp Volker|Issakidis-Bourguet Emmanuelle|Kandlbinder Andrea|Lamkemeyer Petra|Laxa Miriam|Li Wenxue|Miginiac-Maslow Myroslawa|Schöttler Mark A|Tognetti Vanesa B|Weis Engelbert

  7. Neuropsychological assessment, neuroimaging, and neuropsychiatric evaluation in pediatric and adult patients with sickle cell disease (SCD

    Directory of Open Access Journals (Sweden)

    Christopher L Edwards

    2007-01-01

    Full Text Available Christopher L Edwards1, Renee Dunn Raynor1, Miriam Feliu1, Camela McDougald1, Stephanie Johnson2, Donald Schmechel3, Mary Wood1, Gary G Bennett4, Patrick Saurona5, Melanie Bonner1, Chante’ Wellington1, Laura M DeCastro6, Elaine Whitworth6, Mary Abrams6, Patrick Logue1, Lekisha Edwards1, Salutario Martinez7, Keith E Whitfield81Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA; 2American Psychological Association, Science Directorate, Washington, DC, USA; 3Department of Medicine, Division of Neurology, Duke University Medical Center, Durham, NC, USA; 4Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA, USA; 5Taub Institute For Research on Alzheimer’s Disease and The Aging Brain, Columbia University, New York, NY, USA; 6Department of Medicine, Division of Hematology, Duke University Medical Center, Durham, NC, USA; 7Department of Radiology, Duke University Medical Center, Durham, NC, USA; 8Duke University, Durham, NC, USAAbstract: Traditionally, neuropsychological deficits due to Sickle Cell Disease (SCD have been understudied in adults. We have begun to suspect, however, that symptomatic and asymptomatic Cerebrovascular Events (CVE may account for an alarming number of deficits in this population. In the current brief review, we critically evaluated the pediatric and adult literatures on the neurocognitive effects of SCD. We highlighted the studies that have been published on this topic and posit that early detection of CVE via neurocognitive testing, neuropsychiatric evaluations, and neuroimaging may significantly reduce adult cognitive and functional morbidities.Keywords: cerebral vascular event, neuropsychological assessment, sickle cell disease, neuroimaging

  8. Occurrence of Sciadicleithrum mexicanum Kritsky, Vidal-Martinez et Rodríguez-Canul, 1994 (Monogenea: Dactylogyridae in the Cichlid Cichlasoma urophthalmus from a flooded quarry in Yucatan, Mexico

    Directory of Open Access Journals (Sweden)

    E. F. Mendoza-Franco

    1995-06-01

    Full Text Available Cichlids, Cichlasoma urophthalmus, collected in a flooded quarry in the Yucatan Peninsula, Mexico, from January through June 1992, had high levels of infection with the ancyrocephaline Sciadicleithrum mexicanum (Monogena: Dactylogyridade in all montlhly samples. Neither occurrence nor maturation of the worms eshibited any pronounced monthly fluctuation. The infection rate was found to be sizedependent, greater in longer fish. The worms occurred on primary lamellae of gill filaments of all arches, with lower numbers of parasites attached to the fourth gill arch. Otherwise, there was no significant site preference of worms. Only minor histopathological changes were found at the sites of attachment, and these were restricted to the epithelial cells of the primary lamellae of thegill filaments. The lack of seasonal periodicity in this tropical monogenean is compared to seasonal cycles typical of temperate species.

  9. Occurrence of Sciadicleithrum mexicanum Kritsky, Vidal-Martinez et Rodríguez-Canul, 1994 (Monogenea: Dactylogyridae) in the Cichlid Cichlasoma urophthalmus from a flooded quarry in Yucatan, Mexico

    OpenAIRE

    Mendoza-Franco,E. F.; Vidal-Martínez,V.; Simá-Álvarez,R.; Rodríguez-Canul,R.; Vivas-Rodríguez,C.; Scholz,T.

    1995-01-01

    Cichlids, Cichlasoma urophthalmus, collected in a flooded quarry in the Yucatan Peninsula, Mexico, from January through June 1992, had high levels of infection with the ancyrocephaline Sciadicleithrum mexicanum (Monogena: Dactylogyridade) in all montlhly samples. Neither occurrence nor maturation of the worms eshibited any pronounced monthly fluctuation. The infection rate was found to be sizedependent, greater in longer fish. The worms occurred on primary lamellae of gill filaments of all ar...

  10. Response to Martinez-Novack et al. Comments on Hynes et al. Prevalence of Marijuana Use among University Students in Bolivia, Colombia, Ecuador, and Peru. Int. J. Environ. Res. Public Health, 2015, 12, 5233-5240

    Directory of Open Access Journals (Sweden)

    Marya Hynes

    2015-09-01

    Full Text Available We have read with great interest the Comments related to the article entitled “Prevalence of marijuana use among university 20 students in Bolivia, Colombia, Ecuador and Peru” and appreciate the readers’ feedback [1]. [...

  11. Redescription of Philometra margolisi Moravec, Vidal-Martinez et Aguirre-Macedo, 1995 (Nematoda: Philometridae), a gonad-infecting parasite of the red grouper Epinephelus morio (Serranidae) in the Gulf of Mexico

    Czech Academy of Sciences Publication Activity Database

    Moravec, František; Bakenhaster, M.; Leone, E. H.

    2017-01-01

    Roč. 62, č. 2 (2017), s. 412-421 ISSN 1230-2821 R&D Projects: GA ČR(CZ) GBP505/12/G112 Institutional support: RVO:60077344 Keywords : Nematode parasite * Dracunculoidea * marine fish * USA * seasonal occurrence Subject RIV: EG - Zoology OBOR OECD: Zoology Impact factor: 1.160, year: 2016

  12. LA GIMNASIA CEREBRAL Y LA CREATIVIDAD DE LOS NIÑOS Y LAS NIÑAS DE 4 A 5 AÑOS DE EDAD DE LA UNIDAD EDUCATIVA LUIS A MARTINEZ DEL CANTÓN AMBATO PROVINCIA DEL TUNGURAHUA

    OpenAIRE

    Salazar Garcés, María Cristina

    2016-01-01

    El mundo actual requiere seres humanos con formación integral que fusione conocimientos, habilidades, destrezas, valores, la presente investigación sobre la gimnasia cerebral y la creatividad de los niños y las niñas de 4 a 5 años de edad de la Unidad Educativa Luis A. Martínez del Cantón Ambato, Provincia de Tungurahua, tiene como finalidad investigar el nivel de desarrollo de la creatividad de los niños mencionados, aplicando para ello encuestas dirigidas a los docentes, entrevistas a las a...

  13. Defending the Amazon: Conservation, Development and Security in Brazil

    Science.gov (United States)

    2009-03-01

    Globo, August 6, 2008, http://oglobo.globo.com/ economia /miriam/post.asp?t=rota_das_drogas&cod_Post=118173&a=496 (accessed February 24, 2009). 193...oglobo.globo.com/ economia /miriam/post.asp?t=rota_das_drogas&cod_Post =118173&a=496 (accessed February 24, 2009). Levitsky, Melvyn (U.S. Ambassador

  14. Four of the south americans working at CERN

    CERN Document Server

    Laurent Guiraud

    1999-01-01

    Peruvian Jose Lamas Valverde (at back), and Brazilians (clockwise from right) Miriam Gandelman, Erica Polycarpo and Leandro de Paula Le peruvien Jose Lamas Valverde (au fond) et (dans le sens des aiguilles d'une montre, a partir du centre) les bresiliens Miriam Gandelman, Erica Polycarpo et Leandro de Paula

  15. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Miriam Petitti1 Antonello A Barresi1 Daniele L Marchisio1. Dipartimento di Scienza Applicata e Tecnologia, Istituto di Ing. Chimica, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italia ...

  16. Reference: 712 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available t cell Delledonne Massimo|Dietz Karl-Josef|Finkemeier Iris|Jones Alex M E|Laxa Miriam|Mattè Alessandro|Perazzolli Michele|Romero-Puertas Maria C|Vandelle Elodie|Zaninotto Federica

  17. Cellular and molecular biology of filamentous fungi

    National Research Council Canada - National Science Library

    Borkovich, Katherine A; Ebbole, Daniel J

    2010-01-01

    ... AND EXPRESSION OF THE GENETIC CODE / 61 6 Mitotic Cell Cycle Control / 63 COLIN P. C. DE SOUZA AND STEPHEN A. OSMANI 7 Meiosis / 81 CLAIRE BURNS, PATRICIA J. PUKKILA, AND MIRIAM E. ZOLAN 8 DNA Repa...

  18. 77 FR 61755 - Performance Review Board Members

    Science.gov (United States)

    2012-10-11

    ... JULIET COHEN GARY CONNOR SUZI COX VIRGINIA DANIEL KATHERINE DEL VECCHIO PAOLO DELPHIN-RITTMON MIRIAM DEVOSS ELIZABETH DICKINSON ELIZABETH ERNEY JOAN GABRIEL EDWARD GOLDHABER BEN GOTTLICH VICKI HENDERSON...

  19. Horticulture hybrid cultivars and exotic plant invasion: A case study of Wisteria (Fabaceae)

    Science.gov (United States)

    J.L. Trusty; B.G. Lockaby; W.C. Zipperer; L.R. Goertzen

    2008-01-01

    Ornamental plant horticulture has had a long history in the USA, beginning with the first botanical garden started by John Bartram in Philadelphia in 1728 (Hedrick, 1988). From this modest start, the nursery and horticulture business in the USA was flourishing by the early 19th century. The growth and sale of useful and attractive plant species inspired American plant...

  20. We are caught up in the inertia of an era of cheap energy, but we shall soon be faced with the frightening flip side on the coin. Interview with Cayetano Lopez Martinez, director of energy at Ciemat; Estamos en la inercia de una epoca de energia barata pero pronto veremos la cara mas temible del problema

    Energy Technology Data Exchange (ETDEWEB)

    Bayo, I. F.

    2008-07-01

    A physicist with a long history of research and an analyst of the worlds energy situation, Cayetano Lopez reflects on the current and future problems of meeting growing worldwide energy demands and looks at alternatives to the current dependence on fossil fuels. (Author)

  1. Biology and Ecology of Sand Flies (Diptera: Psychodidae) in the Middle East, with Special Emphasis on Phlebotomus Papatasi and Phlebotomus Alexandri

    Science.gov (United States)

    2009-03-06

    leishmaniasis vector species. Revista da Sociedade Brasileira de Medicina Tropical 37: 10-14. Peterson, A. T., V. Sanchez-Cordero, C. B. Beard, and J. M...Sociedade Brasileira de Medicina Tropical 37: 10-14. Peterson, A. T., C. Martinez-Campos, Y. Nakazawa, and E. Martinez-Meyer. 2005. Time-specific

  2. 78 FR 8702 - Unblocking of Specially Designated Nationals and Blocked Persons Pursuant to the Foreign...

    Science.gov (United States)

    2013-02-06

    .... DONO MORALES, Edman Manuel, Privada Niza 3617 Int. 2, Colonia Playas de Tijuana, Tijuana, Baja...; R.F.C. QUHM-701022-TL3 (Mexico) (individual) [SDNTK]. 14. RUELAS MARTINEZ, Jose Manuel, 402... (individual) [SDNTK]. 16. RUELAS MARTINEZ, Jose de la Cruz, Calle de la Ventisca 640, Colonia Playas Seccion...

  3. Nutritional and antimicrobial evaluation of Saccharum officinarum ...

    African Journals Online (AJOL)

    Tuoyo Aghomotsegin

    2016-08-17

    Aug 17, 2016 ... and polyphenols as powerful antioxidants (Palmer, 2005;. Martinez and Martinez .... sample were determined by the methods of the Association of. Official Analytical ... Some of the phytochemical compounds were also quantified using ..... P 175. Vila FC, Colombo R, de Lira TO, Yariwake JH (2008). HPLC.

  4. Summary the race to reinvent energy and stop global warming

    CERN Document Server

    2013-01-01

    Complete summary of Fred Krupp and Miriam Horn's book: ""Earth: The Sequel: The Race to Reinvent Energy and Stop Global Warming"". This summary of the ideas from Fred Krupp and Miriam Horn's book ""Earth: The Sequel"" explains how capitalism, as the most powerful economic force in the world, is the only engine of change that has the strength to stop global warming. In their book, the authors demonstrate how this can be achieved by installing a cap-and-trade initiative, providing genuine economic incentives for companies and reducing their carbon footprint. This summary explains their theory in

  5. Determination of radioinduced delay in DNA synthesis in two-garlic-clones cells (Allium Sativum L.)

    International Nuclear Information System (INIS)

    Perez Lezcano, A.; Perez Talavera, S.

    1989-01-01

    To contribute to tech improvement of the use of ionizing radiations as an auxiliary tool in the fitoimprovement, dose-effect curves for the 'Martinez' and 'Sancti Spiritus-3' clones were stablished by using as effect the delay induced by radiations in DNA synthesis determined by the 'Martinez' clone which induces a delay of 50% in reference to the control is approximately 11 Gy, while the dose value for the 'Sancti Spiritus-3' clone is 18 Gy, thus the 'Martinez' clones has a higher sensitivity to radiations than the other clone, therefore it coincides with what we found for these clones other indexes are used as radiosensitivity criteria

  6. Steeling and Resilience in Art Education

    Science.gov (United States)

    Heise, Donalyn

    2014-01-01

    Steel is an incredibly strong alloy of iron and carbon. Due to its incredible strength and durability, this resilient material is commonly used for constructing buildings. The transitive verb "steeling" is defined in Miriam-Webster dictionary as "to fill with resolution or determination, as in, she 'steeled herself to face the…

  7. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. Antonello A Barresi. Articles written in Sadhana. Volume 38 Issue 6 December 2013 pp 1219-1239. CFD modelling of condensers for freeze-drying processes · Miriam Petitti Antonello A Barresi Daniele L Marchisio · More Details Abstract Fulltext PDF. The aim of the present research is the ...

  8. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. Daniele L Marchisio. Articles written in Sadhana. Volume 38 Issue 6 December 2013 pp 1219-1239. CFD modelling of condensers for freeze-drying processes · Miriam Petitti Antonello A Barresi Daniele L Marchisio · More Details Abstract Fulltext PDF. The aim of the present research is the ...

  9. JCSC_129_11_1695_1703_SI.docx

    Indian Academy of Sciences (India)

    Miriam

    MIRIAM NAVLANI-GARCÍA,a PRIYANKA VERMA,a KOHSUKE MORI,*a,b,c YASUTAKA ... Colloid with Pd nanocrystals with various shapes. Figure ... Le Bars J, Specht U, Bradley J S and Blackmond D G 1999 Catalytic probe of the surface of ...

  10. Collection Development: Relaxation & Meditation, September 1, 2010

    Science.gov (United States)

    Lettus, Dodi

    2010-01-01

    One of the first books to document the relationship between stress and physical and emotional health was "The Relaxation Response" by Herbert Benson, M.D., with Miriam Z. Klipper. Originally published in 1975, the book grew out of Benson's observations as a cardiologist and his research as a fellow at Harvard Medical School. Benson's study of…

  11. EDITORIAL PSYCHIATRIC ILLNESS AMONG JUVENILES AND ...

    African Journals Online (AJOL)

    Kateee

    2003-06-01

    Jun 1, 2003 ... Bickel, R. and Campbell, A. Mental health of adolescents in custody: ... aged 8 to 18 years classified as criminal offenders, group I (60), and those for protection ... with poor socio-economic support (15). ..... Chief Residents' Office, The Miriam Hospital, 164 Summit Ave., Main Bldg, Room 344 Providence, RI.

  12. 17 Mzamane 03.pmd

    African Journals Online (AJOL)

    hond

    2007-04-07

    Apr 7, 2007 ... I can't help giggling to myself at the thought of the final showdown in heaven between the two ... After I placed my order I decided to walk to the .... Miriam Tlali's Amandla (1980) and Mongane Serote's To Every Birth its Blood (1979). Ride on the ... hatred, low self-esteem, and inferiority complexes. Sepamla ...

  13. Ergonomics SA - Vol 28, No 2 (2016)

    African Journals Online (AJOL)

    Comparing fatigue responses between healthy individuals and asymptomatic low back pain sufferers - implications for return-to-work: a pilot study · EMAIL FULL TEXT EMAIL FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Miriam C. Mattison, Natalie A. Ross, 2-18. http://dx.doi.org/10.4314/esa.v28i2.2 ...

  14. 76 FR 45848 - Draft Environmental Impact Statement on a Denali Park Road Vehicle Management Plan for Denali...

    Science.gov (United States)

    2011-08-01

    ... meetings, and solicits comments on the DEIS. DATES: Comments on the DEIS must be received no later than... public meetings. FOR FURTHER INFORMATION CONTACT: Miriam Valentine, Park Planner, Denali National Park... Memorial Day and a week after Labor Day. As tourism in Alaska has increased, so have demands for visits...

  15. JCSC_129_11_1661_1669_SI.docx

    Indian Academy of Sciences (India)

    Priyanka Verma

    PRIYANKA VERMA,a MIRIAM NAVLANI-GARCÍA,a YASUTAKA KUWAHARA,a,b KOHSUKE MORI,a,b,c and HIROMI YAMASHITA*a,b. aDivision of Materials and Manufacturing Science, Graduate School of Engineering, Osaka University, 2-1 Yamada-oka, Suita, Japan. bUnit of Elements Strategy Initiative for Catalysts ...

  16. Mentoring the modern African surgeon: A call to arms!

    African Journals Online (AJOL)

    2011-01-16

    Jan 16, 2011 ... Hospital, Nairobi, 2-University of Nairobi, Kenya, 3-King Khalid University, UAE. Correspondence: Dr. Miriam Mutebi, Aga Khan. University Hospital. P.O. Bx 30270 .... Galukande M, Kijjambu S, Luboga S Improving recruitment of surgical trainees and training of surgeons in Uganda. East. Cent Afr J Surg.

  17. Browse Title Index

    African Journals Online (AJOL)

    Items 451 - 500 of 592 ... Vol 15, No 1 (2013), Safe injections and waste management at a Sub-Saharan regional hospital: a quantitative descriptive study, Abstract PDF. Elisabeth Darj, Josefine Nilsson, Andrea Barnabas Pembe, Miriam Urasa. Vol 7, No 3 (2005), Sampling mosquitoes with CDC light trap in rice field and ...

  18. Sevilla suhtekomöödia vs Sevilla kiredraama / Kristina Kõrver

    Index Scriptorium Estoniae

    Kõrver, Kristina, 1979-

    2008-01-01

    Kahest ooperist Soome Rahvusooperis - Gioacchino Rossini "Sevilla habemeajaja", lavastaja Giancarlo del Monaco, dirigent Miguel Gomez-Martinez ja Georges Bizet "Carmen", lavastaja Arnaud Bernard, dirigent Alberto Hold-Garrido

  19. Single nucleotide polymorphism in genome-wide association of ...

    African Journals Online (AJOL)

    Mohd Fareed

    2012-09-25

    Sep 25, 2012 ... Codeine, Tramadol, Acetaminophen. CYP2C9. Celecoxib .... Pharmacogenet- ics of acute azathioprine toxicity: relationship to thiopurine ... Martinez C, Cueto R,. Garcia-Martin E. Pharmacogenomics in drug induced liver.

  20. Raidpere Veneetsia biennaalile

    Index Scriptorium Estoniae

    2005-01-01

    2005. aastal esindab 51. Veneetsia kunstibiennaalil Eestit fotograaf Mark Raidpere oma väljapanekuga "Varjupaik", mille koostab kunstikriitik Hanno Soans. Kuraatorid Maria Corral (Kunsti kogemus) ja Rosa Martinez (Alati pisut eespool)

  1. Siluriformes, Loricariidae

    Indian Academy of Sciences (India)

    2013-04-04

    Apr 4, 2013 ... JULIANA DE FÁTIMA MARTINEZ1, ROBERTO LARIDONDO LUI1,. ROBERTO ... Paulo (MZUSP) under voucher numbers MZUSP 110802,. MZUSP .... Foresti F., Oliveira C. and Almeida-Toledo L. F. 1993 A method for.

  2. Parkinson's Disease Videos

    Medline Plus

    Full Text Available ... Diagnosis PD, Now What? Managing the First Few Years with Parkinson's Expert Briefings: Pain in PD Expert ... Salud en General, Parte 2 CareMAP: Life Beyond This Life Dra. Claudia Martinez, MAPC - Parkinson- Pasion, Positivismo ...

  3. 78 FR 16244 - Sunshine Act Meeting

    Science.gov (United States)

    2013-03-14

    ..., 132 S.Ct. 694 (2012) or Christian Legal Society v. Martinez 130 S.Ct. 2971 (2010) Litigation--Speakers... broader conflict between anti-discrimination norms and civil liberties-- Speakers' Remarks and Questions...

  4. 76 FR 21796 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2011-04-18

    .... Carson Dan B. Clark Gregory L. Cooper Kenneth D. Craig Terry J. Dare Christopher A. Deadman Vincent C... Roberto E. Martinez Travis W. Neiwert Barbara C. Pennington Luis H. Sanchez George K. Sizemore James A...

  5. Effects of different combinations and concentrations of growth ...

    African Journals Online (AJOL)

    PRECIOUS

    2009-11-16

    Nov 16, 2009 ... artificial seed (Büyükalaca and Mavituna, 1995; Vicient and Martinez .... light stimulated somatic embryo formation and maturation in Brassica napus. .... Effects of Abscisic Acid on Somatic Embryogenesis and Induction of.

  6. Parkinson's Disease Videos

    Medline Plus

    Full Text Available ... Does a Caregiver Need to Know About Cognitive Impairment? Dra. Claudia Martinez, MAPC - Parkinson- Pasion, Positivismo y ... Beyond This Life What Medications Help with Cognitive Impairment? What Are Some Tips for Following a Medication ...

  7. Homme avatakse Veneetsia biennaal / Johannes Saar

    Index Scriptorium Estoniae

    Saar, Johannes, 1965-

    2005-01-01

    51. kunstibiennaalist Veneetsias. Eestit esindab fotograaf Mark Raidpere isikunäitus "Isolaator". Kuraatorinäitusi on kaks. Kuraatorid Maria de Coral ja Roza Martinez Hispaaniast. Biennaali Kuldlõvi antakse elutöö eest Barbara Krugerile

  8. 75 FR 52393 - Proposed Data Collection; Comment Request: New Markets Tax Credit (NMTC) Program-Allocation...

    Science.gov (United States)

    2010-08-25

    ... DEPARTMENT OF THE TREASURY Community Development Financial Institutions Fund Proposed Data... Institutions (CDFI) Fund, Department of the Treasury, is soliciting comments concerning the New Markets Tax... comments to Rosa Martinez, Acting NMTC Program Manager, Community Development Financial Institutions Fund...

  9. ETUDE DE LA DISTRIBUTION DES CATIONS ECHANGEABLES

    African Journals Online (AJOL)

    SEI Joseph

    1991) 400 pp. [15] - P. Ondina, « Gasteropodos terrestres de A Coruna y Pontevedra ». Tesis Doctoral. Universitat De Santiago. (1988) 386 p. [16] - A. Martinez - Orti, « Moluscos terrestres testaceos de la comunidad Valenciana ». Tesis Doctoral ...

  10. S(l)pirituality. Immersive Worlds as a Window to Spirituality Phenomena.

    OpenAIRE

    Martinez-Zárate, Pablo; Corduneanu, Isabela; Martinez, Luis Miguel

    2008-01-01

    Pablo Martinez-Zárate, Isabela Corduneanu and Luis Miguel Martinez outline in their article “S(l)pirituality. Immersive Worlds as a Window to Spirituality Phenomena” some conceptual and methodological considerations for studying influential belief systems within online worlds, in particular “Second Life.” The authors' research is aimed at tracing the activities and narratives surrounding of the avatar’s development inside digital worlds, focusing their attention on spiritual practices as perf...

  11. Persistence of Lactobacillus Reuteri DSM17938 in the Human Intestinal Tract: Response to Consecutive and Alternate-Day Consumption with Varying Storage Conditions

    Science.gov (United States)

    2011-08-25

    mechanisms of defense by lactic acid bacteria: effective dose. J Dairy Sci 82: 863-869, 1999. 5. Fuller R. Reasons for the apparent variation in the... fermented milk containing Lactobacillus casei. J Nutr Health Aging 8: 208-211, 2004. 10. Parra MD, Martinez de Morentin BE, Cobo JM, Mateos A and...Martinez JA. Daily ingestion of fermented milk containing Lactobacillus casei DN114001 improves innate- defense capacity in healthy middle-aged people

  12. Chile: Civil-Military Relations and Democratic Consolidation

    Science.gov (United States)

    1998-12-01

    Publishers, 1992), 41. 26 Javier Martinez and Alvaro Diaz , Chile The Great Transformation (Harrisonburg, Virginia: The Brookings Institution, 1996...the world economy, by means of technological advancements, makes it necessary to reduce 32 Javier Martinez and Alvaro Diaz , Chile the Great...disapproves the executive’s budget. There is no 60 Alicia Frohman, "Chile: External Actors and the Transition to Democracy," in Beyond Sovereignty

  13. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. Horacio Rivera. Articles written in Journal of Genetics. Volume 91 Issue 2 August 2012 pp 241-244 Research Note. De novo inv(17)(p11.2q21.3) in an intellectually disabled girl: appraisal of 21 inv(17) constitutional instances · Miriam Partida-Pérez María G. Domínguez Vivian Alejandra ...

  14. Quantum Phases at the Nanoscale

    Science.gov (United States)

    2002-07-20

    Sapienza" Roma. (Ital)y and Consejo perpendicular magnetic field, independent Nacional de Investigaciones Cientificas y electrons occupy Landau levels...Electromodulation of charge transfer and Departamento de Fisica Teorica de la the breathing mode of C60 on graphite Materia Condensada, Spain Miriam del...Instituto de Ciencia de Materiales de Madrid- epitaxial ferromagnetic metal [4], exhibiting CSIC. Spain coherent dynamics that persist over time scales

  15. Formalising Living Labs to achieve organisational objectives in emerging economies

    CSIR Research Space (South Africa)

    Smit, D

    2011-05-01

    Full Text Available Conference Proceedings Paul Cunningham and Miriam Cunningham (Eds) IIMC International Information Management Corporation, 2011 ISBN: 978-1-905824-24-3 Formalising Living Labs to Achieve Organisational Objectives in Emerging Economies Danie SMIT1... organisation, a university) in the innovation process. In contrast to closed- innovation where firms only use internal sources, open-innovation suggests the companies use both external and internal sources. This shift in innovation paradigm becomes more...

  16. Spinning droplets: non-first generation East and Southeast Asian Australian poets and the discourse of water

    OpenAIRE

    McFarlane, Rosalind Nicole

    2017-01-01

    Poetry written by diasporic Asian groups in Australia has been gaining increasing attention, especially with the 2013 release of Contemporary Asian Australian Poets edited by Adam Aitken, Kim Cheng Boey and Michelle Cahill, the first anthology of this kind of work. This thesis aims to be the first instance of sustained critical attention paid to many of the poets included in this anthology, including Adam Aitken, Ivy Alvarez, Lachlan Brown, Lily Chan, Bella Li, Debbie Lim, Miriam Wei Wei Lo, ...

  17. Preferences of patients undergoing hemodialysis – results from a questionnaire-based study with 4,518 patients

    OpenAIRE

    Janssen, Inger M.; Gerhardus,Ansgar; von Gersdorff,Gero; Schaller,Mathias; Barth,Claudia; Scheibler,Fueloep; Baldamus,Conrad

    2015-01-01

    Inger Miriam Janssen,1 Ansgar Gerhardus,2,3 Gero D von Gersdorff,4 Conrad August Baldamus,4 Mathias Schaller,4 Claudia Barth,5 Fueloep Scheibler6 1Department of Epidemiology and International Public Health, Bielefeld University, Bielefeld, Germany; 2Department for Health Services Research, University of Bremen, Bremen, Germany; 3Health Sciences Bremen, University of Bremen, Bremen, Germany; 4Department of Internal Medicine II, University Hospital of Cologne, Cologne, Germany; 5KfH K...

  18. Where Corporate Culture and Local Markets Meet. Music and Film Majors in the Netherlands, 1990-2005

    OpenAIRE

    Kamp, Miriam

    2009-01-01

    textabstractSince the 1980s, media and entertainment companies have developed into large cross-media multinationals. Their international structure, strategy and operation have been investigated extensively. However, these majors operate globally by having local offices in various markets. So far, little attention has been paid to this aspect. In Where Corporate Culture and Local Markets Meet, Miriam van de Kamp addresses the local operation of international music and film corporations in the ...

  19. Intelligent fractions learning system: implementation

    CSIR Research Space (South Africa)

    Smith, Andrew C

    2011-05-01

    Full Text Available Conference Proceedings Paul Cunningham and Miriam Cunningham (Eds) IIMC International Information Management Corporation, 2011 ISBN: 978-1-905824-24-3 An Intelligent Fractions Learning System: Implementation Andrew Cyrus SMITH1, Teemu H. LAINE2 1CSIR... to fractions. Our aim with the current research project is to extend the existing UFractions learning system to incorporate automatic data capturing. ?Intelligent UFractions? allows a teacher to remotely monitor the children?s progress during...

  20. Central extensions of cotangent universal hierarchy: (2+1)-dimensional bi-Hamiltonian systems

    International Nuclear Information System (INIS)

    Sergyeyev, Artur; Szablikowski, Blazej M.

    2008-01-01

    We introduce the cotangent universal hierarchy that extends the universal hierarchy from [L. Martinez Alonso, A.B. Shabat, Phys. Lett. A 300 (1) (2002) 58, (nlin.SI/0202008); A.B. Shabat, Theor. Math. Phys. 136 (2003) 1066; L. Martinez Alonso, A.B. Shabat, J. Nonlinear Math. Phys. 10 (2) (2003) 229, (nlin.SI/0310036); L. Martinez Alonso, A.B. Shabat, Theor. Math. Phys. 140 (2) (2004) 1073, (nlin.SI/0312043); A. Shabat, J. Nonlinear Math. Phys. 12 (Suppl. 1) (2005) 614]. Then we construct a (2+1)-dimensional double central extension of the cotangent universal hierarchy and show that this extension is bi-Hamiltonian. This yields, as a byproduct, the central extension of the original universal hierarchy

  1. A comparison of different quasi-newton acceleration methods for partitioned multi-physics codes

    CSIR Research Space (South Africa)

    Haelterman, R

    2018-02-01

    Full Text Available & structures, 88/7, pp. 446–457 (2010) 8. J.E. Dennis, J.J. More´, Quasi-Newton methods: motivation and theory. SIAM Rev. 19, pp. 46–89 (1977) A Comparison of Quasi-Newton Acceleration Methods 15 9. J.E. Dennis, R.B. Schnabel, Least Change Secant Updates... Dois Metodos de Broyden. Mat. Apl. Comput. 1/2, pp. 135– 143 (1982) 25. J.M. Martinez, A quasi-Newton method with modification of one column per iteration. Com- puting 33, pp. 353–362 (1984) 26. J.M. Martinez, M.C. Zambaldi, An Inverse Column...

  2. Quasi-Newton methods for the acceleration of multi-physics codes

    CSIR Research Space (South Africa)

    Haelterman, R

    2017-08-01

    Full Text Available .E. Dennis, J.J. More´, Quasi-Newton methods: motivation and theory. SIAM Rev. 19, pp. 46–89 (1977) [11] J.E. Dennis, R.B. Schnabel, Least Change Secant Updates for quasi- Newton methods. SIAM Rev. 21, pp. 443–459 (1979) [12] G. Dhondt, CalculiX CrunchiX USER...) [25] J.M. Martinez, M.C. Zambaldi, An Inverse Column-Updating Method for solving large-scale nonlinear systems of equations. Optim. Methods Softw. 1, pp. 129–140 (1992) [26] J.M. Martinez, On the convergence of the column-updating method. Comp. Appl...

  3. Parkinson's Disease Videos

    Medline Plus

    Full Text Available ... el Comportamiento, Parte 1 CareMAP: Medicamentos y la Salud en General, Parte 1 Expert Briefings: Apathy or ... Caregiving Hallucinations and Delusions CareMAP: Medicamentos y la Salud en General, Parte 2 Dra. Claudia Martinez, MAPC - ...

  4. Efecto del flujo turbulento, la condición superficial, la presencia de ácido acético y un compuesto orgánico usado como inhibidor de corrosión sobre la cinética electroquímica del acero api 5l x52 en soluciones con co2 disuelto /

    OpenAIRE

    Olvera Martínez, María Elena

    2012-01-01

     tesis que para obtener el grado de Doctorado en Ingeniería, presenta Maria Elena Olvera Martinez ; asesor Juan Mendoza Flores310 páginas : ilustracionesDoctorado en Ingeniería UNAM, Facultad de Química, 2012

  5. Art and social health. Sociocultural program participation for people with funcional diversity

    Directory of Open Access Journals (Sweden)

    María Martínez Lemos

    2015-12-01

    Full Text Available Martinez, M. y Rodríguez, J. (2015: “Arte y salud social. Programas de participación sociocultural para personas con diversidad funcional”, Revista Española de Discapacidad, 3 (2: 125-131.

  6. Disease: H00481 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available -1172-2-7 ... PMID:21552474 ... AUTHORS ... Garcia-Hoyos M, Auz-Alexandre CL, Almoguera B, Cantalapiedra D, Riveiro...-Alvarez R, Lopez-Martinez MA, Gimenez A, Blanco-Kelly F, Avila-Fernandez A, Trujillo-Tiebas MJ, Garcia-Sand

  7. Acute effects of copper and lead on some blood parameters on ...

    African Journals Online (AJOL)

    user

    2011-04-18

    Apr 18, 2011 ... micrograms/L (Martinez et al., 2004). High levels of heavy metals cause environmental pollution, especially in water body. Water pollution with heavy metals, affects various physiological processes in fish, including blood cells. In fish, toxic substances taken up from the water enter the blood and therefore, ...

  8. 21st International Conference on DNA Computing and Molecular Programming

    Science.gov (United States)

    2016-05-24

    M, Nand K. More specifically, a solution CRN Cis represented through the valuation of r and p , which are extracted from the model returned by Z3...aldonado, Eric Martinez , Robert T. Schweller, and Tim Wylie University of Texas Rio Grande Valley , Edinburg, TX 78539-2999, USA {camer on . chalk01 , b

  9. 140 miljonit

    Index Scriptorium Estoniae

    2006-01-01

    Sotheby oksjonil müüdi 20. saj. abstraktse kunsti olulisema autori Jackson Pollocki umbes 2,5 x 1,25 meetri suurune teos "No. 5, 1948". Uus omanik Mehhiko ärimees David Martinez, endine omanik Hollywoodi meelelahutusärimees David Geffen

  10. Validating the Riverside Acculturation Stress Inventory with Asian Americans

    Science.gov (United States)

    Miller, Matthew J.; Kim, Jungeun; Benet-Martinez, Veronica

    2011-01-01

    An emerging body of empirical research highlights the impact of acculturative stress in the lives of culturally diverse populations. Therefore, to facilitate future research in this area, we conducted 3 studies to examine the psychometric properties of the Riverside Acculturation Stress Inventory (RASI; Benet-Martinez & Haritatos, 2005) and its 5…

  11. National PTA Gets Connected with Social Media

    Science.gov (United States)

    Phillips, Derek

    2011-01-01

    People are busy, we all know that. Getting their attention is harder and harder all the time. That's especially true for member organizations and advocacy groups. The National PTA is both and has adapted some social media practices to reach out and maintain contact with more than 5 million volunteers in 25,000 local units. James Martinez, senior…

  12. This is where computing science hits the tangible, the palpable world. It is the next frontier

    CERN Multimedia

    Shankar, Mallikarjun

    2006-01-01

    Mr Martinez is a computer scientist. He was drawn to the task of remotely monitoring a hostile environment around the clock because he wanted the challenge of trying to bring together the various different technologies such sensor webs need. (1 page)

  13. JCSC_129_06_0657_0661_SI.docx

    Indian Academy of Sciences (India)

    Muddamarri Hanumantha Rao (Dr)

    P. Politzer, Y. Ma, P. Lane, M. C. Concha, Computational Prediction of Standard Gas, Liquid, and Solid-phase Heats of Formation and Heats of Vaporization and ... P. Politzer, J. Martinez, J. S. Murray, M. C. Concha, A. Toro-Labbé, An Electrostatic Interaction Correction for Improved Crystal Density Prediction, Mol. Phys.

  14. Discursive Enactments of the World Health Organization's Policies: Competing Cultural Models in Tanzanian HIV/AIDS Prevention

    Science.gov (United States)

    Higgins, Christina

    2010-01-01

    In the healthcare arena, language policy-related research has thus far been limited to questions about "language access," i.e., whether individuals are supplied with health information in their languages, and whether interpreters for doctor-patient consultations are provided (Martinez 2008; Ngo-Metzger et al. 2003; Partida 2007; Vahabi…

  15. NATO Advanced Research Workshop: Optics of Biological Particles. Held in Novosibirsk, Russia on 3-6 Oct 2005

    Science.gov (United States)

    2005-01-01

    non-destructive character. It makes the method very at- tractive for pharmaceutical and biotechnological industries applications. Liposomes are close...Martinez, Javier A., B.Sc. (in Physics) Institute of Materials and Reagents (IMRE), University of Havana Zapata y G, El Vedado, Plaza de la Revolucion

  16. Qualitative Inquiry with Women in Poverty in Mexico City: Reflections on the Emotional Responses of a Research Team

    Science.gov (United States)

    Martinez-Salgado, Carolina

    2009-01-01

    While conducting a qualitative inquiry involving in-depth interviews on the perceptions of health risks within a group of profoundly poor urban families in the southern part of Mexico City, Martinez-Salgado and her interdisciplinary team of women interviewers got involved in emotionally complex situations with the women participants in the study.…

  17. Moskva, lootuse ja lootusetuse dialektika / Reet Varblane

    Index Scriptorium Estoniae

    Varblane, Reet, 1952-

    2005-01-01

    Moskva I rahvusvaheline kaasaja kunsti biennaal "Lootuse dialektika" endises Lenini muuseumis 28. I-28. II. Kuraatorid Joseph Backstein, Daniel Birnbaum, Nicolas Bourriaud, Iara Boubnova, Rosa Martinez ja Hans Ulrich Obrist. Kunstnike Keskmajas eksponeeritud Marat Gelmani kuraatoriprojekti "Venemaa 2" Moskva linnakohtusse kaebamisest õigeusklike poolt. 2. III toimunud kohtuistungist Sahharovi keskuse näituse "Ettevaatust religioon!" korraldajate tegevuse asjus

  18. Veneetsia pärgab sotsiaalkriitikuid / Johannes Saar

    Index Scriptorium Estoniae

    Saar, Johannes, 1965-

    2005-01-01

    13. juunil avatud Veneetsia 51. kunstibiennaalist. Rahvuspaviljonidest, preemiasaajaid. Elutööpreemia sai Barbara Kruger, kuraatoripreemiad Rosa Martinez ja Maria de Corral. Eestit esindab Mark Raidpere, kuraator Hanno Soans. Kesk-Aasia paviljonist lisas "Tapetud vaikitakse maha". Usbeki, Kirgiisi ja Kasahstani kunstnike ühisnäituse kuraator on Viktor Misiano Moskvast

  19. 78 FR 28701 - Unblocking of Specially Designated Nationals and Blocked Persons Pursuant to Executive Order 12978

    Science.gov (United States)

    2013-05-15

    ... property and interests in property were blocked pursuant to the Order: 1. ARBOLEDA ARROYAVE, Pedro Nicholas (a.k.a. ARBOLEDA ARROYAVE, Pedro Nicolas), c/o DEPOSITO POPULAR DE DROGAS S.A., Cali, Colombia; c/ o...., Bogota, Colombia; Cedula No. 11352426 (Colombia) (individual) [SDNT]. 4. DUQUE MARTINEZ, Diego Fernando...

  20. Genetics Home Reference: Peutz-Jeghers syndrome

    Science.gov (United States)

    ... high risk of developing cancer during their lifetimes. Cancers of the gastrointestinal tract, pancreas, cervix, ovary, and breast are among the most ... of cancers in the Peutz-Jeghers syndrome. Clin Cancer Res. 2006 May 15;12(10):3209-15. ... Martinez-Gimeno M, Carballo M. De novo germline mutation in the serine-threonine kinase ...

  1. Highland Medical Research Journal - Vol 5, No 1 (2007)

    African Journals Online (AJOL)

    Evaluation of Nutritional Status and Hydration in Patients on Chronic Hemodialysis by Bioelectrical Impedance Analysis · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. A H Tzamaloukas, E I Agaba, A Onime, D J VanderJagt, I Ma, A Lopez, R Martinez, R A Tzamaloukas, R H ...

  2. Evaluation of antioxidant activities in captive-bred cultured yellow seahorse, Hippocampus kuda (Bleeker, 1852).

    Digital Repository Service at National Institute of Oceanography (India)

    Sanaye, S.V.; Pise, N.M.; Pawar, A.P.; Parab, P.P.; Sreepada, R.A.; Pawar, H.B.; Revankar, A.D.

    Chem. 119, 123–132. Martinez-Alvarez, R.M., Morales, A.E., Sanz, A., 2005. Antioxidant defences in fish: Biotic and abiotic factors. Rev. Fish Biol. Fish. 15, 75–88. Matsukawa, R., Dubinsky, Z., Kishimoto, E., Masaki, K., Masuda, Y., Takeuchi, T...

  3. Role of Protein Synthesis Initiation Factors in Dietary Soy Isoflavone-Mediated Effects on Breast Cancer Progression

    Science.gov (United States)

    2014-08-01

    of genistein and other flavonoids in human breast cancer cells in vitro, Nutr Cancer, 27: 31-40, 1997. 13 de la,P.C., Otero-Franqui,E., Martinez...properties of genistein and other flavonoids in human breast cancer cells in vitro, Nutr Cancer, 27: 31-40, 1997. 3 Okabe,Y., Shimazu,T. and Tanimoto,H

  4. Combustion synthesis of graphene and ultracapacitor performance

    Indian Academy of Sciences (India)

    graphite is treated with strong acids and oxidants. Although the detailed ... Colloidal suspension of graphitic oxide in water is chemi- cally reduced using ..... Wakeland S, Martinez R, Grey J K and Luhrs C 2010 Carbon. 48 3463. Wang G, Yang ...

  5. Molecular Mechanism of Nkx3.1 Deregulation and its Function in Murine Pten Prostate Cancer Model

    Science.gov (United States)

    2006-09-01

    One possible explanation is that Pten null cells have become ‘‘ addicted ’’ to high levels of PI3K/AKT activity and, consequently, are hypersensitive...H.H., Kertesz, N., Lesche, R., Whale , A.D., Martinez-Diaz, H., Rozengurt, N., Cardiff, R.D., et al. (2003). PTEN tumor suppressor regulates p53 protein

  6. Parkinson's Disease Videos

    Medline Plus

    Full Text Available ... el Comportamiento, Parte 1 CareMAP: Medicamentos y la Salud en General, Parte 1 Expert Briefings: Apathy or ... CareMAP: Caring from Afar CareMAP: Medicamentos y la Salud en General, Parte 2 Dra. Claudia Martinez, MAPC - ...

  7. Some helminth parasites of Epinephelus morio (Pisces: Serranidae) from the peninsula of Yucatan, Mexico

    NARCIS (Netherlands)

    Moravec, F.; Vidal-Martínez, V.M.; Aguirre-Macedo, M.L.

    1995-01-01

    Moravec, F., V.M. Vidal-Martinez & M.L. Aguirre-Macedo, 1995. Some helminth parasites of Epinephelus morio (Pisces: Serranidae) from the Peninsula of Yucatan, Mexico. Studies Nat. Hist. Caribbean Region 72: 55-68. One nematode species, Hysterothylacium eurycheilum, the acanthocephalan Gorgorhynchus

  8. Institutional and Structural Barriers to Latino/a Achievement

    Science.gov (United States)

    Valenzuela, Angela; Garcia, Emmanuel; Romo, Harriett; Perez, Beatrix

    2012-01-01

    The problem of low academic attainment for Latino/a students may be a result of the situation at the K-12 levels, a situation that is beyond the control of students or their families (Martinez, 2003). Analyses of school success must take into account the social and political hierarchies in schools, school systems, and communities, as well as the…

  9. Prospects for bioprocess development based on recent genome advances in lignocellulose degrading basidiomycetes

    Science.gov (United States)

    Chiaki Hori; Daniel Cullen

    2016-01-01

    Efficient and complete degradation of woody plant cell walls requires the concerted action of hydrolytic and oxidative systems possessed by a relatively small group of filamentous basidiomycetous fungi. Among these wood decay species, Phanerochaete chrysosporium was the first to be sequenced (Martinez et al. 2004). In...

  10. Prevalence of Besnoitia besnoiti antibodies in bovine sera and milk ...

    African Journals Online (AJOL)

    ADEYEYE

    2014-02-04

    Feb 4, 2014 ... to pass undiagnosed, antibody detection is required for screening the ... livestock in the country. Materials and .... majority of host animals (Cantu-Martinez et al., ... biologically stable IgA and IgM could be transferred to infants ...

  11. 77 FR 74186 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2012-12-13

    ... Logistics, Inc. (NVO & OFF), 7685 NW. 80th Terrace, Medley, FL 33166, Officers: Hugo E. Martinez, Secretary... & OFF), 1834 Harden Blvd., Lakeland, FL 33803, Officers: Steven C. Pniewski, Manager (QI), Manuel R. Echevarria, President, Application Type: New NVO & OFF License, Global Wide Logistics, Inc. (NVO), 1937 Davis...

  12. Research

    African Journals Online (AJOL)

    abp

    Received: 22/10/2016 - Accepted: 16/08/2017 - Published: 27/09/2017. Abstract. Introduction: ..... Tate JE, Burton AH, Boschi-Pinto C, Steele AD, Duque J,. Parashar UD. ... Barril PA, Martinez LC, Giordano MO, Castello AA, Rota RP, Isa.

  13. Protein Kinase Pathways That Regulate Neuronal Survival and Death

    Science.gov (United States)

    2004-08-01

    The neurotrophic effects of 2. Apostolides, C., E. Sanford, M. Hong, and 1. Mendez . 1998. Glial fibroblast growth factors on dopaminergic neurons in...Vaudry D, Falluel-Morel A, Leuillet S, Vaudry H, Gonzalez B) (2003) Reg- Martinez-Murillo R, Caro L, Nieto-Sampedro M (1993) Lesion-induced ulators

  14. Becoming Something Different: Learning from Esme

    Science.gov (United States)

    Fairbanks, Colleen M.; Crooks, Penny Mason; Ariail, Mary

    2011-01-01

    In this article, Fairbanks, Crooks, and Ariail followed Esme Martinez, a Spanish-speaking Latina, from the sixth grade to the eleventh grade, focusing on her perspectives of schooling and her shifting identities related to home, school, friendships, and future. Drawing on the construct of artifacts, a sociohistorical concept that understands…

  15. 77 FR 23059 - Endangered and Threatened Wildlife and Plants; Determination of Endangered Status for Three Forks...

    Science.gov (United States)

    2012-04-17

    ..., modification, and curtailment due to soil erosion and sedimentation during storm events. Also, we have found... Slaughter Ranch Museum, including Snail Spring, Horse Spring, Goat Tank Spring, and perhaps Tule Spring (Cox... to two springs on the John Slaughter Ranch Museum, Goat Tank Spring and Horse Spring (Martinez 2010...

  16. allele of the noncoding hsrω gene of Drosophila melanogaster is not ...

    Indian Academy of Sciences (India)

    , Martinez P. et al. 2000 Identification of genes that modify ataxin-1-induced neurodegeneration. Nature 408, 101–. 106. Lakhotia S. C. 2003 The non-coding, developmentally active and stress inducible hsrω gene of Drosophila melanogaster ...

  17. Impact of divalent dopant Ca on the electrical properties of ZnO by ...

    Indian Academy of Sciences (India)

    [9] Barsoukov E and Macdonald J R (eds) 2005 Impedance spectroscopy: theory, experiment, and applications, 2nd edn. (New York: John Wiley & Sons Inc.) [10] Barranco A P, Pinar F C, Martinez O P, Guerra D L S and. Carmenate G 1999 J. Eur. Ceram. Soc. 19 2677. [11] Muthukumarn S and Gopalkrishan R 2012 Opt.

  18. Lessons from the Field.

    Science.gov (United States)

    Gibbs, Lois; And Others

    1995-01-01

    Presents examples of four communities that successfully organized against a community environmental threat. Profiles the fight against racism in Newtown, GA; efforts to maintain coalitions in Tifton, GA; action against exposure to dioxin in Columbus, OH; and activism against an illegal sludge dump on the Torres-Martinez Reservation (Cahuilla), CA.…

  19. Teaching Students in Place: The Languages of Third Space Learning

    Science.gov (United States)

    Morawski, Cynthia M.

    2017-01-01

    With a perceptive eye cast on geoscience pedagogy for students labeled as disabled, Martinez-Álvarez makes important contributions to the existing conversation on placed-based learning. It is in our local backyards, from the corner basketball court, to the mud bank of a city lake, to the adjacent field where rocky outcrops spill down to a…

  20. Methods to Reduce Sand Ejecta from Projectile Impact - a Scaled Study with the Goal of Application to Depleted Uranium Penetrator Catch Boxes

    Science.gov (United States)

    2012-04-01

    organization provided high-speed camera support. This work was conducted under the general supervision of Andy Martin , Chief, EP-E, and Warren...bomb attack: Studies with uranium and metal stimulants. Environmental Progress 26(1):94-103. Ormo, J., M. Lindstrom , A. Lepinette, J. Martinez-Frias

  1. Kõnnitee kindlusesse / Andres Kurg

    Index Scriptorium Estoniae

    Kurg, Andres, 1975-

    1998-01-01

    Arhitektid José Martinez Lapena ja Elias Torres Tur ääristasid siksakina mäekülge mööda Castelldefelsi kindlusse viiva jalakäijaste tee Barcelonas raudbetooni ja sakilise roostevärvi Corten terasega

  2. Antibacterial activity and probiotic properties of some Lactic Acid ...

    African Journals Online (AJOL)

    Client

    2013-05-15

    May 15, 2013 ... genes (Mataragas et al., 2002; Jamuna and Jeevartnam,. 2004). ... The agar spot test was a modification of that described by Tomé et al. (2006). Overnight ..... Martinez-bueno, Galvez A, Valdivia E, Maqueda M (1990). A.

  3. Targeting Civilians with Indiscriminate Violence

    Science.gov (United States)

    2008-03-01

    turning against small merchants, entrepreneurs and petty bourgeoisie who had formed the backbone of the Islamic opposition. The GIA activists began...evidence recorded in France in 1996. In The Algerian Civil War 1990- 1998, ed. Martinez, 152. 157 Amnesty International 1997b: 18. In “The Logic of

  4. Science and Technology of Nanostructured Magnetic Materials: Proceedings of a NATO Advanced Study Institute Conference Held in Aghia Pelaghia, Crete, Greece on 24 June -6 July 1990. NATO ASI Series B: Physics. Volume 259

    Science.gov (United States)

    1990-07-06

    C.N. Afonso, A.N. Lagunas , F. Briones and S. Giron J. Magn. Magn. Mat. 62 (1980) 833. B. Martinez, A. Ruiz, A. Labarta, X. Obradors, F. Briones...Magn. Mater. 50, 265 (1985). 35. T. Tokunaga, M. Harada, M. Ohkoshi, S. Honda and T. Kusuda, IEEE Trans. MAG-22, 940 (1986). 36. H. Heitmann, M

  5. Partisan Differences on Higher Education Accountability Policy: A Multi-State Study of Elected State Legislators

    Science.gov (United States)

    Morse, Andrew Q.

    2014-01-01

    Public institutions in the United States face a policy challenge to adapt to accountability expectations among a variety of stakeholders (Bogue & Hall, 2012; Thelin, 2004; Richardson & Martinez, 2009). Among the major stakeholders are state legislators who hold fiscal and policy influence over public institutions, but these leaders have…

  6. Strategies of the protozoan parasite Entamoeba histolytica to evade ...

    Indian Academy of Sciences (India)

    Unknown

    and the subsequent migration of the amoeba to the liver where abscesses are formed (Espinosa-Cantellano and. Martinez-Paloma 2000; Stanley 2001). ..... activity of bacterial peroxiredoxins; Nature (London) 407. 211–215. Cario E and Podolsky D K 2000 Differential alteration in intes- tinal epithelial cell expression of ...

  7. Parkinson's Disease Videos

    Medline Plus

    Full Text Available ... How Is Parkinson's Disease Diagnosed? CareMAP: Managing Caregiver Stress CareMAP: Getting Dressed CareMAP: End-of-Life Care ... Salud en General, Parte 2 CareMAP: Rest and Sleep: Part 2 Dra. Claudia Martinez, MAPC - Parkinson- Pasion, ...

  8. Towards the Development of an Academic Word List for Applied Linguistics Research Articles

    Science.gov (United States)

    Khani, Reza; Tazik, Khalil

    2013-01-01

    Academic vocabulary, as the most challenging aspect of language learning in EAP and ESP contexts, has received much attention in the last few decades (e.g. Laufer, 1988; Sutarsyah, et al., 1994; Laufer and Nation, 1999; Coxhead, 2000; Nation, 2001a, 2001b; Wang et al., 2008; Martinez et al., 2009). The major attainments of these studies were…

  9. Disease: H01797 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available pituitarism, post-natal microcephaly, visual and renal anomalies. ... JOURNAL ... Brain 136:3096-105 (2013) DOI:10.1093/brain/awt218 ..., Chong WK, Alkuraya FS, Martinez-Barbera JP, Sowden JC, Dattani MT ... TITLE ... ARNT2 mutation causes hypo

  10. Maintenance of Epithelial Stem Cells by Cbl Proteins

    Science.gov (United States)

    2013-09-01

    corresponding authors). • Mohibi S, Gurumurthy CB, Nag A, Wang J, Mirza S, Mian Y, Quinn M, Katafiasz B, Eudy J, Pandey S, Guda C, Naramura M, Band H...MMTV-polyoma middle T transgenic mice. Cancer Res 67: 167–177. doi:10.1158/0008-5472.CAN-06-3782. 41. Li G, Robinson GW, Lesche R, Martinez-Diaz H

  11. 75 FR 76284 - Pesticide Tolerance Crop Grouping Program II; Revisions to General Tolerance Regulations

    Science.gov (United States)

    2010-12-08

    ... scabrum Mill 8-10A Goji berry, Lycium barbarum L 8-10A Groundcherry, Physalis alkekengi L., P. 8-10A grisea (Waterf.) M. Martinez, P. peruviana L., P. pubescens L. Martynia, Proboscidea louisianica 8-10B, 8... aethiopicum L. 8-10B, 8-10C Sunberry, Solanum retroflexum Dunal..... 8-10A Tomatillo, Physalis philadelphica...

  12. Microparticles

    African Journals Online (AJOL)

    (DOAJ), African Journal Online, Bioline International, Open-J-Gate and Pharmacy ... Polymeric drug delivery systems ... carrier systems based on available literature [10- .... the formulation were close, but the polydispersity .... significantly difference (p < 0.05) from the ... Pacheco PD, Manrique JY, Martinez F. Thermodynamic.

  13. The Dushak–Erekdag Survey of roAp Stars Tatyana Dorokhova ...

    Indian Academy of Sciences (India)

    South-African Astronomical Observatory (SAAO). Details of the discovery and further studies are given in Kurtz (1990) and Kurtz & Martinez (2000). Some roAp stars have multiple modes of pulsations and they are valuable for asteroseismological studies. Out of the 32 known roAp stars so far, about 84% were discovered in ...

  14. Signature of Spanish Traineeship Collaboration Agreement between CERN and CIEMAT

    CERN Multimedia

    Redondo Esteban, Isabel

    2015-01-01

    Signature of the collaboration agreement for the training of young Spanish engineers and applied physicists in key CERN technologies. CIEMAT represented by D. Cayetano Lopez Martinez, Director-General. CERN represented by Dr. Jose Miguel Jimenez, Head of Technology Department. In presence of Ms Maria Luisa Poncela Garcia, Secretary-General for Science, Technology and Innovation. Ministry of Economy and Competitiveness.

  15. Teoretiske og eksperimentelle dynamiske undersøgelser af jernbanekøretøjer

    DEFF Research Database (Denmark)

    Jensen, Jens Christian

    1995-01-01

    by the theory of Shen, Hedrick and Elkins. The derivation of the dynamical equations is described, and special focus is placed on the contact between wheel and rail. This contact is treated locally elastic which means that the wheel is allowed to penetrate the rail. This method is capable of taking into account...... multiple coexisting contact areas between the wheel and rail. Various examples of the geometrical contact between wheel and rail are given and the influence of track gauge and rail inclination on the contact is outlined. The contact-geometry for a worn wheel-profile on new rails is determined and used...... in the simulations of the dynamics of the IC3 train. In the thesis the dynamics are numerically investigated for the IC3 running on three different track configurations: 1) A perfectly straight track 2) A measured track with irregularities 3) A curve When running on a straight track, we follow the linear...

  16. Dynamic Surface Control and Its Application to Lateral Vehicle Control

    Directory of Open Access Journals (Sweden)

    Bongsob Song

    2014-01-01

    Full Text Available This paper extends the design and analysis methodology of dynamic surface control (DSC in Song and Hedrick, 2011, for a more general class of nonlinear systems. When rotational mechanical systems such as lateral vehicle control and robot control are considered for applications, sinusoidal functions are easily included in the equation of motions. If such a sinusoidal function is used as a forcing term for DSC, the stability analysis faces the difficulty due to highly nonlinear functions resulting from the low-pass filter dynamics. With modification of input variables to the filter dynamics, the burden of mathematical analysis can be reduced and stability conditions in linear matrix inequality form to guarantee the quadratic stability via DSC are derived for the given class of nonlinear systems. Finally, the proposed design and analysis approach are applied to lateral vehicle control for forward automated driving and backward parallel parking at a low speed as well as an illustrative example.

  17. Supporting material for EBT-P review presentation at DOE Germantown, 9-11 January 1980: working notes

    International Nuclear Information System (INIS)

    Sheffield, J.

    1980-01-01

    This memorandum reviews the EBT theory of Hedrick et al., and using a model of the EBT-1/S plasma simplifies the transport equations to a few relations involving the radial electric field, radial flow, diffusion coefficients, input power and measured plasma parameters. A summary is given of EBT-1/S experimental data with reference data sets and best data sets. Theory and experiment are compared and it is shown that the electron diffusion is classical within a factor of 1.5. The proposed EBT-1/S program is reviewed and it is shown how it is designed to provide information for EBT-P in a timely fashion and fill in the gaps of knowledge in the EBT-1/S studies. Finally a brief discussion is given of EBT-Q and it is shown how the EBT-P program is designed to provide information for this ignition device

  18. Lateral dynamic features of a railway vehicle

    DEFF Research Database (Denmark)

    Gao, Xue-jun; True, Hans; Li, Ying-hui

    2016-01-01

    The lateral dynamic features of a railway vehicle are investigated using two similar wheel/rail contact models: the Vermeulen-Johnson and the Shen-Hedrick-Elkins models. The symmetric/asymmetric bifurcation behaviour and chaotic motions of the railway vehicle are investigated in great detail......, resulting in problems for safe operation of the vehicle. Therefore, it should be avoided in everyday operation. Furthermore, the creation of multiple solution branches suggests that the critical speed of a vehicle should be determined from a comprehensive analysis of the various kinds of possible...... by varying the speed and using the resultant bifurcation diagram' method. It is found that multiple solution branches exist and they can lead to more steady states in the dynamic behaviour of the railway vehicle. The coexistence of multiple steady states can lead to jumps in the amplitude of oscillations...

  19. Assessing the accuracy of different simplified frictional rolling contact algorithms

    Science.gov (United States)

    Vollebregt, E. A. H.; Iwnicki, S. D.; Xie, G.; Shackleton, P.

    2012-01-01

    This paper presents an approach for assessing the accuracy of different frictional rolling contact theories. The main characteristic of the approach is that it takes a statistically oriented view. This yields a better insight into the behaviour of the methods in diverse circumstances (varying contact patch ellipticities, mixed longitudinal, lateral and spin creepages) than is obtained when only a small number of (basic) circumstances are used in the comparison. The range of contact parameters that occur for realistic vehicles and tracks are assessed using simulations with the Vampire vehicle system dynamics (VSD) package. This shows that larger values for the spin creepage occur rather frequently. Based on this, our approach is applied to typical cases for which railway VSD packages are used. The results show that particularly the USETAB approach but also FASTSIM give considerably better results than the linear theory, Vermeulen-Johnson, Shen-Hedrick-Elkins and Polach methods, when compared with the 'complete theory' of the CONTACT program.

  20. Isoenzymatic variability in progeny of Pinus mugo Turra x Pinus sylvestris L. hybrids from Bór na Czerwonem, in experimental culture

    Directory of Open Access Journals (Sweden)

    Maria A. Bobowicz

    2014-01-01

    Full Text Available The article describes the genetic structure of 12-year old seedlings. They were grown in an experimental culture representing the progeny of natural hybrids of Pinus mugo Turra and Pinus sylvestris L. from the peatbog Bór na Czerwonem. The studies were carried out on seedlings, employing electrophoresis of enzymatic proteins from winter buds. Parallel isoenzymatic analyses were also conducted for trees of P. mugo Turra from Tatra Mountains and for P. sylvestris L. trees from Białowieża in order to determine similarities of the hybrids to the 'pure' species, thought to represent parental forms, and for natural hybrids from Bór na Czerwonem. The obtained electrophoretic patterns made the determination of genetic structure of the population possible, namely of the observed heterozygosity, expected heterozygosity, Wright's fixation index and coefficients of similarity according to Nei and Hedrick. Genetic distances between the populations were also estimated. The variability of 11 enzymatic loci demonstrated the highest level of variability in the population of hybrids. Coefficients of genetic differentiation (GST and of gene flow, (Nm suggested a close relationship of the hybrids to P. mugo which may indicate an introgressive type of the hybrid swarm, from which the studied trees originated. The analysis of genetic similarity coefficients, according to Nei and Hedrick, demonstrated also an extensive similarity of the two hybrid groups to P. mugo. However, upon analysis of individual enzymatic loci, some of them highly resembled P. mugo while others were similar to P. sylvestris. The closest genetic similarity was demonstrated for the group of hybrids from the peatbog and the respective of hybrides group from culture. The variable gene expression as well as asymmetric inheritance of isoenzymes provided additional evidence of the introgressive character of the studied trees from the hybrid population.

  1. BioModels.net Web Services, a free and integrated toolkit for computational modelling software.

    Science.gov (United States)

    Li, Chen; Courtot, Mélanie; Le Novère, Nicolas; Laibe, Camille

    2010-05-01

    Exchanging and sharing scientific results are essential for researchers in the field of computational modelling. BioModels.net defines agreed-upon standards for model curation. A fundamental one, MIRIAM (Minimum Information Requested in the Annotation of Models), standardises the annotation and curation process of quantitative models in biology. To support this standard, MIRIAM Resources maintains a set of standard data types for annotating models, and provides services for manipulating these annotations. Furthermore, BioModels.net creates controlled vocabularies, such as SBO (Systems Biology Ontology) which strictly indexes, defines and links terms used in Systems Biology. Finally, BioModels Database provides a free, centralised, publicly accessible database for storing, searching and retrieving curated and annotated computational models. Each resource provides a web interface to submit, search, retrieve and display its data. In addition, the BioModels.net team provides a set of Web Services which allows the community to programmatically access the resources. A user is then able to perform remote queries, such as retrieving a model and resolving all its MIRIAM Annotations, as well as getting the details about the associated SBO terms. These web services use established standards. Communications rely on SOAP (Simple Object Access Protocol) messages and the available queries are described in a WSDL (Web Services Description Language) file. Several libraries are provided in order to simplify the development of client software. BioModels.net Web Services make one step further for the researchers to simulate and understand the entirety of a biological system, by allowing them to retrieve biological models in their own tool, combine queries in workflows and efficiently analyse models.

  2. Weiterentwicklung Gruppenleiter/innen-Kurs: Ein Projekt in der Freiwilligenarbeit des CVJM/CVJF Regionalverband Basels: Projektbericht

    OpenAIRE

    Fankhauser, Miriam

    2016-01-01

    Im folgenden Bericht geht es um das Projekt «Weiterentwicklung Gruppenleiter/innen-Kurs – Ein Pro- jekt in der Freiwilligenarbeit des CVJM/CVJF Regionalverband Basels». Dieses Projekt wurde von der Studentin Miriam Fankhauser im Rahmen der Praxisausbildung an der Hochschule Luzern für Soziale Arbeit durchgeführt. In Auftrag gegeben wurde das Projekt vom CVJM/CVJF Regionalverband Basel. Beim eben genannten Projekt ging es darum, den Gruppenleiter/innen-Kurs weiterzuentwickeln. Der Kurs rich...

  3. Note e recensioni

    Directory of Open Access Journals (Sweden)

    Autori Vari

    2012-10-01

    Full Text Available Adriano Ardovino, Raccogliere il mondo. Per una fenomenologia della rete [Angela Maiello] • Clive Bell, L’Arte [Filippo Focosi] • Alessandro Bertinetto, Il pensiero dei suoni. Temi di filosofia della musica [Domenica Lentini] • Terrence Deacon, Incomplete Nature. How Mind Emerged From Matter [Mariagrazia Portera] • Roger Scruton, La bellezza. Ragione ed esperienza estetica [Filippo Focosi] • Miriam Bratu Hansen, Cinema and Experience. Sigfried Kracauer, Walter Benjamin and Theoder W. Adorno [Domenico Spinosa] • Lawrence Barsalou, scritti sulla “Grounded Cognition” [Gialuca Consoli] • Dis-forme, Università degli Studi di Palermo, 28-29 maggio 2012 [Michele Bertolini e Pietro Conte

  4. Neuropsychological effects and attitudes in patients following electroconvulsive therapy

    OpenAIRE

    Edwards, Christopher

    2008-01-01

    Miriam Feliu1,2, Christopher L Edwards1,2,3, Shiv Sudhakar4, Camela McDougald1, Renee Raynor5, Stephanie Johnson6, Goldie Byrd7, Keith Whitfield8, Charles Jonassaint8, Heather Romero1, Lekisha Edwards1, Chante’ Wellington1, LaBarron K Hill9, James Sollers, III9, Patrick E Logue11Department of Psychiatry and Behavioral Sciences; 2Duke Pain and Palliative Care Center; 3Department of Medicine, Division of Hematology; 4Drexel University Medical School; 5Brain Tumor Center, Duke Universi...

  5. m-Living Labs, A framework for collaborative community advancement

    CSIR Research Space (South Africa)

    Buitendag, A

    2012-05-01

    Full Text Available that will allow any HTML5 content to be used easily on any platform without the need to convert it for the hardware it is to run on. This means that the user of a desktop application may use the same application while mobile without the need to get a modified... Conference Proceedings Paul Cunningham and Miriam Cunningham (Eds) IIMC International Information Management Corporation, 2012 ISBN: 978-1-905824-34-2 Copyright ? 2012 The authors www.IST-Africa.org/Conference2012 Page 1 of 10 m-Living Labs...

  6. Surveillance of Travel-Related Mosquito-borne Illness in Rhode Island.

    Science.gov (United States)

    Alang, Neha; Glavis-Bloom, Justin; Alexander-Scott, Nicole; Mermel, Leonard A; Mileno, Maria D

    2016-07-01

    Malaria and Dengue are some of the common infections occurring in persons traveling to countries endemic for these infections. Chinkungunya virus infection is another illness that can occur in people who have travelled to areas endemic for chikungunya virus infection. Herein we report cases of malaria, dengue, and chikungunya in Newport Hospital, The Miriam Hospital and Rhode Island Hospital between January 1, 2010 and December 31, 2014. [Full article available at http://rimed.org/rimedicaljournal-2016-07.asp, free with no login].

  7. Systematic integration of experimental data and models in systems biology.

    Science.gov (United States)

    Li, Peter; Dada, Joseph O; Jameson, Daniel; Spasic, Irena; Swainston, Neil; Carroll, Kathleen; Dunn, Warwick; Khan, Farid; Malys, Naglis; Messiha, Hanan L; Simeonidis, Evangelos; Weichart, Dieter; Winder, Catherine; Wishart, Jill; Broomhead, David S; Goble, Carole A; Gaskell, Simon J; Kell, Douglas B; Westerhoff, Hans V; Mendes, Pedro; Paton, Norman W

    2010-11-29

    The behaviour of biological systems can be deduced from their mathematical models. However, multiple sources of data in diverse forms are required in the construction of a model in order to define its components and their biochemical reactions, and corresponding parameters. Automating the assembly and use of systems biology models is dependent upon data integration processes involving the interoperation of data and analytical resources. Taverna workflows have been developed for the automated assembly of quantitative parameterised metabolic networks in the Systems Biology Markup Language (SBML). A SBML model is built in a systematic fashion by the workflows which starts with the construction of a qualitative network using data from a MIRIAM-compliant genome-scale model of yeast metabolism. This is followed by parameterisation of the SBML model with experimental data from two repositories, the SABIO-RK enzyme kinetics database and a database of quantitative experimental results. The models are then calibrated and simulated in workflows that call out to COPASIWS, the web service interface to the COPASI software application for analysing biochemical networks. These systems biology workflows were evaluated for their ability to construct a parameterised model of yeast glycolysis. Distributed information about metabolic reactions that have been described to MIRIAM standards enables the automated assembly of quantitative systems biology models of metabolic networks based on user-defined criteria. Such data integration processes can be implemented as Taverna workflows to provide a rapid overview of the components and their relationships within a biochemical system.

  8. Vibrational spectra of water solutions of azoles from QM/MM calculations: effects of solvation.

    Science.gov (United States)

    Tanzi, Luana; Ramondo, Fabio; Guidoni, Leonardo

    2012-10-18

    Using microsolvation models and mixed quantum/classical ab initio molecular dynamics simulations, we investigate the vibrational properties of two azoles in water solution: pyrazole and oxazole. The effects of the water-azole hydrogen bonding are rationalized by an extensive comparison between structural parameters and harmonic frequencies obtained by microsolvation models. Following the effective normal-mode analysis introduced by Martinez et al. [Martinez et al., J. Chem. Phys. 2006, 125, 144106], we identify the vibrational frequencies of the solutes using the decomposition of the vibrational density of states of the gas phase and solution dynamics. The calculated shifts from gas phase to solution are fairly in agreement with the available experimental data.

  9. Concert | The CERN Choir hits the high notes | Victoria Hall | 30 September

    CERN Multimedia

    2014-01-01

    60 – 40 – 25: a series of numbers that have inspired an exceptional concert. They refer to the 60th anniversary of CERN, the 40th anniversary of the CERN Choir and the 25th anniversary of its direction by Gonzalo Martinez. On the occasion of this collision of anniversaries, the Committee of this CERN club decided to organise an appropriately significant event to celebrate the important worldwide role that CERN has played for 60 years, the fact that the CERN Choir has brought together amateur singers for 40 years, and finally the decisive role in the Choir’s history of its director, Gonzalo Martinez.   The work chosen for this concert also had to be something exceptional. A work which, through its monumental status, its brilliance, its innovation, its originality and its energy, symbolises CERN’s scientific discoveries, reflects the genius of its creator and represents the highest creative ambitions: Beethoven’s Missa Solemnis.  Perfor...

  10. Concert | The CERN Choir hits the high notes | Victoria Hall | 30 September

    CERN Document Server

    2014-01-01

    60 – 40 – 25: a series of numbers that have inspired an exceptional concert. They refer to the 60th anniversary of CERN, the 40th anniversary of the CERN Choir and the 25th anniversary of its direction by Gonzalo Martinez. On the occasion of this collision of anniversaries, the Committee of this CERN club decided to organise an appropriately significant event to celebrate the important worldwide role that CERN has played for 60 years, the fact that the CERN Choir has brought together amateur singers for 40 years, and finally the decisive role in the Choir’s history of its director, Gonzalo Martinez.   The work chosen for this concert also had to be something exceptional. A work which, through its monumental status, its brilliance, its innovation, its originality and its energy, symbolises CERN’s scientific discoveries, reflects the genius of its creator and represents the highest creative ambitions: Beethoven’s Missa Solemnis.  Perfo...

  11. Adapting Traditional Ideas for a New Reality: Cosmographers and Physicians Updating Astrology to Encompass the New World.

    Science.gov (United States)

    Lanuza Navarro, Tayra M C

    2016-08-01

    This paper aims to demonstrate that astrology was one of the disciplines that most strongly experienced the process that led European natural philosophers, once they were confronted with the nature of the New World, to recognise that previous knowledge was not as complete or absolute as previously assumed, and that the content of several disciplines had to be renewed, both epistemologically and methodologically. This paper focuses on the work by the cosmographer Henrico Martinez, Repertorio de los tiempos (1606), in which he established the astrological influences specific to Mexico, and the work Sitio, naturatezay propiedades de la Ciudad de Mexico (1618) by the physician Diego Cisneros, who refuted Martinez's astrology for Mexico and created his own instructions for the use of astrology in the practice of medicine in New Spain.

  12. Vitamin D deficiency: A potential risk factor for Clostridium difficile infection

    Directory of Open Access Journals (Sweden)

    Youssef D

    2012-10-01

    Full Text Available Dima Youssef,1 William B Grant,2 Alan N Peiris3,41Department of Internal Medicine, Division of Infectious Diseases, 2Sunlight, Nutrition and Health Research Center, San Francisco, CA USA; 3Department of Medicine, Mountain Home VAMC, 4Department of Medicine, East Tennessee State University, Johnson City, Tennessee, USAIn the July 3, 2012 issue of the journal of Risk Management and Healthcare Policy, Martinez et al present a nice review on Clostridium difficile (C. difficile infections.1 The different manifestations of this challenging disease along with the high cost and burden on the health care system were discussed. While the authors did an admirable job in discussing traditional risk factors, they do not mention vitamin D deficiency.View original paper by Martinez and colleagues.

  13. Growth hormone transgenic tilapia (Oreochromis sp.) compensate for increased metabolic rate to preserve exercise performance and hypoxia tolerance

    DEFF Research Database (Denmark)

    McKenzie, D.J.; Martínez, R.; Morales, A.

    2001-01-01

    Transgenic tilapia hybrids (Oreochromis mossambicus × O. hornorum) carrying a single copy of a homologous cDNA growth hormone exhibit higher growth rates than their wild-type conspecifics (Martinez et al. 1999). Swimming respirometry was employed to determine whether the increased growth rate...... higher in transgenics, such that aerobic scope was similar in both groups, and there was no difference in maximum sustainable U (5.2 ± 0.5 vs. 4.5 ± 0.7 bl s-1 in transgenics vs. wild-types, respectively). Following 2 h recovery from exercise, tilapia were exposed to progressive hypoxia (stepwise......Pa, respectively). The results indicate that stimulation of growth consequent to ectopic expression of growth hormone in transgenic tilapia (Martinez et al. 1999) is linked to increased rates of maintenance metabolism. The swimming and hypoxia experiments indicate, however, that the transgenics were able...

  14. West Europe Report, No. 2134.

    Science.gov (United States)

    1983-04-28

    attend a newly convened session. 39 Possibility of New Stoppages Management’s attitude has been characterized by Justo Fernandez , secretary general of the...to judge his work. He has provincial exper- ience; and the leader of a party is formed here. Gerardo Iglesias needs time to assert.himself and become...34 The minister of the interior did not provide any information. Criminal lawyers Jose Antonio Perez Andres, Gonzalo Martinez-Fresneda and Jaime Sanz de

  15. Technical Reference Manual to Allied Medical Publication 7.5 (AMedP 7.5) NATO Planning Guide for the Estimation of CBRN Casualties

    Science.gov (United States)

    2016-10-01

    Friday. When values were rounded to whole weeks, the set of seven incubation periods was the same for exposure dates of Tuesday through Thursday. Since...Undulant Fever.” Public Health Reports 53, no. 20 (1938): 796–803. Hartzell, Joshua D., Robert N. Wood- Morris , Luis J. Martinez, and Richard F...Fox, John M. Boyce, Daniel C. Anderson, Morris E. Potter, William J. Martone, and Charlotte M. Patton. “Airborne Spread of Brucellosis.” Annals of the

  16. Match them, if you can! The similarity between brand personality and endorser personality as determinant of perceived fit and purchase intentions

    OpenAIRE

    Bekk, Magdalena; Spörrle, Matthias; Felser, Georg

    2009-01-01

    Objectives. The match-up hypothesis states that endorsements will be more effective in advertisements when there is congruence between endorser (i.e., a celebrity) and endorsed product (e.g., Till & Busler, 2000). Unlike most previous research, which has mainly dealt with attractiveness and expertise, this study examines the match-up hypothesis based on personality. Methods. The three cross-culturally stable (sincerity, excitement, sophistication; Aaker, Benet-Martinez, & Garolera, 2001) ...

  17. Banking Crises, Deposit Insurance, and Market Discipline: Lessons from the Asian Crises

    OpenAIRE

    Kaoru Hosono; Hiroko Iwaki; Kotaro Tsuru

    2005-01-01

    We investigate the effectiveness of market discipline by depositors during the period of 1992-2002 in the four crisis-hit Asian countries: Indonesia, Korea, Malaysia and Thailand. In Indonesia, the crises first weakened and then strengthened market, which is consistent with the wake-up-call effect found for the Latin American crisis-hit countries (Martinez Peria and Schmukler, 2001). Unlike Indonesia, we could not find an increase in depositors' responsiveness to bank risk after the crisis in...

  18. American Society for Microbiology: Annual Meeting

    Science.gov (United States)

    1992-01-01

    Central - Arkansas, Louisiana, Oklahoma, and Texas 8 = Mountain - Arizona, Colorado, Idaho, Montana. Nevada. New Mexico , Utah. and Wyoming 9 = Pacific...MYCOPLASMAS S4. Thr.•::.:2,at~o:: , "ransformed Cell Lines Expressing Regulatory Genes of Varicella -Zoster Virus. H. MORIUCHI,* M. MORIUCHI, S. E. STRAUS, and...Swimming Pool Waters in Mexico City. (001) P. RAMIREZ,* B. MARTINEZ, E. Wednesday, 8:30 A.M., Room 87 ROBLES, A. DURAN, and V. RIVERA. ENEP-lztacala, UNAM

  19. An Axisymmetric View of Concentric Eyewall Evolution in Hurricane Rita (2005)

    Science.gov (United States)

    2012-08-01

    of Hurricane Hugo (1989). Mon. Wea. Rev., 136, 1237–1259. Martinez, Y., G. Brunet, and M. K. Yau, 2010: On the dynamics of two-dimensional hurricane ...An Axisymmetric View of Concentric Eyewall Evolution in Hurricane Rita (2005) MICHAEL M. BELL Naval Postgraduate School, Monterey, California, and... Hurricane Research Division, Miami, Florida WEN-CHAU LEE National Center for Atmospheric Research,* Boulder, Colorado (Manuscript received 23 June 2011, in

  20. After Saddam: Prewar Planning and the Occupation of Iraq

    Science.gov (United States)

    2008-01-01

    Bernard Kerik; Lieutenant Colonel Chris Kinnan, USAF; Lewis Lucke; William Luti; Roman Martinez; Dayton Maxwell; Michael McNerney; Frank Miller...Post, April 12, 2003; Rupert Cornwell , “U.S.-Backed Iraqis Launch Bid for 28 After Saddam: Prewar Planning and the Occupation of Iraq from a lack...Lori Latif Shak Bernard Hanish Khalid Hassan Foreign procurement DoD DoD – TBD Garabeet Ishaqian Military Industriali- zation Military production

  1. African Journal of Biotechnology - Vol 12, No 2 (2013)

    African Journals Online (AJOL)

    DNA-based population density estimation of black bear at northern Mexico: A preliminary study · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. R Ávalos-Ramírez, L José Mijangos-Araujo, JJ Zarate-Ramos, A Martinez-Muñoz, JA Salinas-Meléndez, L María De ...

  2. Redefining face contour with a novel anti-aging cosmetic product: an open-label, prospective clinical study

    OpenAIRE

    Garre, Aurora; Martinez-Masana, Gemma; Piquero-Casals, Jaime; Granger, Corinne

    2017-01-01

    Aurora Garre,1 Gemma Martinez-Masana,1 Jaime Piquero-Casals,2 Corinne Granger1 1Innovation and Development, ISDIN S.A., Barcelona, Spain; 2Dermik Clinic, Barcelona, Spain Background: Skin aging is accelerated by multiple extrinsic factors: ultraviolet radiation, smoking and pollution increase oxidative activity, damaging cellular and extracellular components such as DNA, proteins, and lipids. With age, collagen and hyaluronic acid levels decline, resulting in loss of elasticity and moisture ...

  3. Construct validity of the physical activity questionnaire for adolescents (paq-a): maximal oxygen uptake

    OpenAIRE

    Benítez-Porres, Javier; Dorado-Guzmán, Manuel; Barrera-Expósito, Jesús; Correas-Gómez, Lorena; Alvero-Cruz, Jose Ramon; Carnero, Elvis A.

    2015-01-01

    Introduction: The Physical Activity Questionnaire for adolescents (PAQ-A) is a cost-effective tool to assess physical activity (PA) patterns during adolescence and it has been widely used in research and field settings. Convergent validity of PAQ-A has been confirmed in several countries (Bervoets et al., 2014; Janz, Lutuchy, Wenthe, & Levy, 2008; Martinez-Gomez et al., 2009). However, the construct validity has often been overlooked. Therefore, the aim of this study was to analyze the constr...

  4. Do Prostate Cancer Exosomes Generate a Field Effect Leading to Tumor Multifocality

    Science.gov (United States)

    2016-04-01

    Undergraduate Research program (to K. Gabriel and E. Frisch), and a generous gift from Melinda and Edward Subia of Orange County CA. Abstract Field effect or...kind gift of Dr. W. Xiao, University of Science and Technology of China, Hefei, China. pLKO.1 control and pLKO.1/EGR-1 shRNA plasmids were from...Pathology and Hospital: Trisha Fleet for procuring prostate tissues through patient consent; Myra Zucker, Cathy Martinez, and Kari Rigg for skillfully

  5. International Symposium on Electrochemical Impedance Spectroscopy (2nd) Held in Santa Barbara, California on 12-17 July 1992 (Extended Abstracts)

    Science.gov (United States)

    1992-01-01

    Aplicada. M.Martinez and S.Bruque, Departamento.de Quimica Inorgknica. Facultad de Ciencias, Universidad de MAlaga, E-29071 Milaga,(SPAIN). Hydrogen...Departamento de QuImica , Universidade de Coimbra, 3049 Coimbra Codex, Portugal Studies of aluminium corrosion in chloride media have been carried out under a...Caixa Postal 68505, CEP: 21945, RJ, Brazil. z-Depto. de Fisico-Qulmica - IQ/UFRJ - RJ, Brazil. 9-Escola de Engenharia - UFRJ - RJ, Brazil. INTRODUCTION

  6. Nutritional Assessment of U.S. Military Academy Cadets at West Point: Part 2. Assessment of Nutritional Intake

    Science.gov (United States)

    1993-10-06

    collection methodology, and to Ms. Carol Baker-Fulco for on-site training of interviewers and recipe specialists. We also wish to express our...recipe specialists. We also wish to thank Ms. Ann LaBrode and Ms. Carol Baker-Fulco for their support in recipe analysis. We are indebted to Mr. Carlo...D.C.: Headquarters, Department of the Army, July 1990. Taylor, P.G., Martinez-Torres, C., Mendez -Castellano, H., et al. The relationship between

  7. United States Air Force Summer Faculty Research Program 1989. Program Technical Report. Volume 2

    Science.gov (United States)

    1989-12-01

    968, June 1987. 22. E. Zielinski , H. Schweizer, S. Hausser, R. Stuber, M. H. Pilkuhn, and G. Weimann,"Systematics of laser operation in GaAs/AlGaAs...Mike Hinman, John Wagnon, Dave Froehlich, Scott Huse, Scott Shyne, and Ken Taylor. 79-3 I. Introduction Pattern Recognition (PR) is an important...many aspects of this research was also greatly appreciated. Finally, I want to thank Audrey Martinez, Al Leverette, Lt. Georke, Dave Fernald and

  8. Excision and Patch Grafting of a Lateral Peyronie's Plaque—Utilizing a Longitudinal “Window” Approach

    Directory of Open Access Journals (Sweden)

    Kathy Lue, BS

    2015-06-01

    Conclusion: A lateral longitudinal incision for PIEG is a feasible technique and may reduce the postoperative morbidity and dissection required with traditional circumcising incision with penile degloving. Larger comparative studies are necessary for further evaluation. Lue K, Emtage JB, Martinez DR, Yang C, and Carrion R. Excision and patch grafting of a lateral Peyronie's plaque—Utilizing a longitudinal “window” approach. Sex Med 2015;3:86–89.

  9. Hypersonic Technology Developments with EU Co-Funded Projects

    Science.gov (United States)

    2010-09-01

    and Hypersonic Systems and Technologies Conference, AIAA-2006-8109, 06-09/11 2006, Canberra, Australia. [18] Karl S., Hannemann K., Steelant J. and...Canberra, Australia. [23] Haidn, O., Ciezki, H., Hannemann , K. and Karl., S., Selected Supersonic Combustion Activities at DLR within the European...LAPCAT Project, 2nd European Conference for Aerospace Sciences (EUCASS), July 2007, Brussels, Belgium. [24] Martinez-Schram J. , Karl S., Hannemann K

  10. Presence and distribution of two sub-species of Eurema agave (Lepidoptera, Pieridae in Costa Rica

    Directory of Open Access Journals (Sweden)

    Jim Cordoba-Alfaro

    2011-06-01

    Full Text Available Austin (1992 reported Eurema a. agave (Cramer 1775 to the Caribbean of Costa Rica. However, he actually had found E. a. millerorum, described by Bousquets & Luis-Martinez (1987 for the Caribbean of Mexico. The presence of Eurema a. agave is confirmed on this paper with information of specimens collected in the Pacific and Atlantic slopes of Costa Rica. Aspects on distribution of both subspecies are included.

  11. EFECTO ANALGESICO DEL LASER EN PUNTOS ASHI, EN PACIENTES GERIATRICOS CON GONOARTROSIS, EVALUANDO EL DOLOR CON ESCALA VISUAL ANALOGA. PREVIA APERTURA DE CANALES TENDINOMUSCULARES

    OpenAIRE

    LUENGAS CRUCES, SARA ELIZABETH

    2010-01-01

    LA GONOARTROSIS, ES EL PADECIMIENTO MAS FRECUENTE EN LA PRACTICA CLINICA REUMATOLOGICA. TIENE UNA PREVALENCIA ALTA EN PERSONAS MAYORES DE 30 ANOS, POR LO QUE YA CONSTITUYE UN PROBLEMA DE SALUD Y FORMA PARTE DE UNA PANDEMIA DE ENFERMEDADES CRONICO-DEGENERATIVAS (VAZQUEZ MARTINEZ F Y ORTIZ ALVAREZ O. LA INVESTIGACION LATINOAMERICANA SOBRE OSTEOARTROSIS. GAC.MED. VOL. IV,1990 PG. 131)EN LOS REPORTES ESTADISTICOS DEL INEGI Y EN LOS SERVICIOS DE CONSULTA EXTERNA DE ESPECIALIDADES DEL IMSS LA PREVA...

  12. A Counterregulatory Mechanism Impacting Androgen Suppression Therapy

    Science.gov (United States)

    2016-08-01

    Present position: Student, Hochschule Mannheim, Mannheim, Germany 2015 - 2015 Verena Martinez Rodriguez, B.Sc., Rotation Student Study area: Hedgehog ...and Childhood, 8th edition Philadelphia: Elsevier Mosby; 2014:1076-1102. 14. Bornstein SR, Wilson DB. Anatomy of the adrenal cortex. In: Martini L...supporting a patho- genic association between aberrant hedgehog signaling and the- comaefibroma development. Abundant expression of GATA4 and its cofactor

  13. Molecular Mechanisms and Treatment Strategies for Obesity-Associated Coronary Artery Disease, an Imminent Military Epidemic

    Science.gov (United States)

    2009-12-01

    inflammation, hepatic steatosis , and atherosclerosis in mice. J Nutr. 2007;137(7):1776-1782. 26. Jehle AW, Gardai SJ, Li S, L insel-Nitschke P, Morimoto K...Martinez-Clemente M, Lopez-Parra M, Arroyo V, Claria J. Obesity-induced insulin resistance and hepatic steatosis are alleviat ed by ome ga-3 fatty acids: a...impaired hepatic insulin sensitivity and respond only partially to PPARγ agonists. Adiponectin-mediated metabolic improvements are associated with

  14. Vitamin D deficiency: A potential risk factor for Clostridium difficile infection

    OpenAIRE

    Youssef, Dima; Grant, William B; Peiris, Alan N

    2012-01-01

    Dima Youssef,1 William B Grant,2 Alan N Peiris3,41Department of Internal Medicine, Division of Infectious Diseases, 2Sunlight, Nutrition and Health Research Center, San Francisco, CA USA; 3Department of Medicine, Mountain Home VAMC, 4Department of Medicine, East Tennessee State University, Johnson City, Tennessee, USAIn the July 3, 2012 issue of the journal of Risk Management and Healthcare Policy, Martinez et al present a nice review on Clostridium difficile (C. difficile) infections.1 The d...

  15. Posttranscriptional Regulation of the Neurofibromatosis 2 Gene

    Science.gov (United States)

    2006-07-01

    signaling and division were downregulated, including an apoptosis - related, putative tumor suppressor gene, LUCA-15, which was downregulated in seven of... embryologically from the outgrowth of the developing brain (Martinez-Morales et al., 2004). It is comprised of two major layers, the inner layer (prospective...eight genes involved with cell signaling and division were down- regulated. These include an apoptosis -related, putative tumor suppressor gene LUCA-15

  16. Transtornos de inicio del comportamiento disruptivo en estudiantes de 8 a 11 años de una institución educativa - Callao

    OpenAIRE

    Baca Pacheco, Flora

    2012-01-01

    This descriptive simple research aimed to determined the beginning of disruptive behavior disorders in the students aged 8-11 years of a public school in Callao. The samples were 100 students aged 8-11 years. The questionnaire for detection of behavior disorders in children and adolescents “ESPERI” of Parellada, San Sebastian and Martinez, (2002) was used. The results showed a severe (serious) level of inattention, impulsivity and hyperactivity, oppositional defiant disorder, pre-disocial per...

  17. VIPER: Chronic Pain after Amputation: Inflammatory Mechanisms, Novel Analgesic Pathways, and Improved Patient Safety

    Science.gov (United States)

    2016-10-01

    Whitney U test for evaluating differences in inflammatory mediators between groups (Case vs. Control) and used nonparametric correlations (Spearman’s rho...responses to acute pain. PAIN 2008;140:135–144. [10] Gordon S, Martinez FO. Alternative activation of macrophages: mechanism and functions...Concentrations in Cases vs. Controls. Mediator Case (n=36) Median (Range) Control (n=40) Median (Range) Mann- Whitney U Test (p value) IFN

  18. Members of the LEP team in front of the final superconducting module to be installed

    CERN Multimedia

    Laurent Guiraud

    1999-01-01

    From left to right: Richard, H; Darrieutort, C; Pollailon, J; Grabowski, F; Losito, R; Insomby, A; Preis, H; Pelletier, S; Bouguenoun, D; Mouillot, G; Rybkowski, D; Varin, B; Vacher, T; Mathis, G; Passeri, M; Martinez, J M; Grillot, S; Myers, S; Deyrail, D; Benamara, M; Chiaveri, E; Hanni, R; Diez, F; Burla, R; Kissler, K H; Pommepuy, M; Esteve, R; Jimenez, J M; Boussard, D; Grimaud, A; Callegari, D; Pestre, P; Hazard, J C.

  19. Grande Sertão: Veredas by João Guimarães Rosa

    Directory of Open Access Journals (Sweden)

    2013-07-01

    Full Text Available "What is a translation that stalls comprehension?" asks Nancy Fumero in her introduction to Felipe W. Martinez' English-language renditions of João Guimarães Rosa's Portuguese poetics. In these translations (presented alongside the Portuguese originals Fumero argues that we encounter "a new form of translation that risks everything in order to encounter the same treacherous knowing Rosa had traversed."

  20. Morphological and molecular diversity in a collection of the Andean tree tomato (Solanum betaceum Cav.)

    OpenAIRE

    Acosta-Quezada, P.G.; Martinez-Laborde, J.B.; Vilanova Navarro, Santiago; Prohens Tomás, Jaime

    2011-01-01

    Instituto Nacional de Investigaciones Agrarias y Agroalimentarias (RF2008-00008-00-00) Acosta-Quezada, P.; Martinez-Laborde, J.; Vilanova Navarro, S.; Prohens Tomás, J. (2011). Morphological and molecular diversity in a collection of the Andean tree tomato (Solanum betaceum Cav.). Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca : Horticulture. 68(1):500-501. http://hdl.handle.net/10251/63083 Senia 500 501 68 1

  1. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. G González-Sprinberg1 R Martinez2 Jorge Vidal3. Instituto de Física, Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay; Departamento de Física, Universidad Nacional, Bogotá, Colombia; Departament de Física Teòrica Universitat de València, Burjassot, València, Spain ...

  2. Steni muinasjutuvõistluse võitjad selgunud / Ants Roos, Ann Roos

    Index Scriptorium Estoniae

    Roos, Ants

    2008-01-01

    Steni XVI muinasjutuvõistluse žüriisse kuulusid: Ann Roos, Ants Roos, Leelo Tungal, Krista Kumberg, Leida Olszak, Ülle Väljataga. Tulemused: I koht Siim Niinelaid, II koht Julius Air Kull, III koht Mihkel Rammu. Žürii eriauhinnad: Anna Kristin Peterson, Elis Ruus, Rain Hallikas, Mariliis Peterson, Marjaliisa Palu, Karl Kirsimäe, Margaret Pulk. Ergutusauhinnad: Karmel Klaus, Martti Kaljuste, Kristina Korell, Mirjam Võsaste, Mihkel Põder, Iirys Kalde, Miriam Jamul, Mari-Ann Mägi, Ketlin Saar, Liisbeth Kirss. Muud eriauhinnad said: Allan Läll, Berle Mees, Anett Kuuse, Karl Erik Kübarsepp, Grete Tamm, Siim Niinelaid, Kaisa Marie Sipelgas, Ellen Anett Põldmaa, Evelin Laul, Karl Laas, Karl Stamm, Kerli Retter

  3. Treating disorganized attachment in the Group Attachment-Based Intervention (GABI©): A case study.

    Science.gov (United States)

    Knafo, Hannah; Murphy, Anne; Steele, Howard; Steele, Miriam

    2018-05-24

    This paper describes the treatment of a mother and child who demonstrated disorganized attachment behaviors in their interactions with one another. The mother, who was diagnosed with Borderline Personality Disorder, felt incapable of managing her aggressive toddler and his emotional needs. The dyad was referred for therapy due to concerns about his developmental progress, evident delays having been mainly attributed to the problems observed within the parent-child relationship. The primary intervention applied to working with the dyad was the Group Attachment-Based Intervention (GABI©), developed by Anne Murphy in collaboration with Miriam Steele and Howard Steele. The mother also received individual psychotherapy as a supplement to the dyadic and group work of GABI©. The process and outcome of this comprehensive approach to treating a vulnerable dyad is explored in this case study. © 2018 Wiley Periodicals, Inc.

  4. Programa especial del ciclo Por la radio en reclamo de la aparición con vida de Jorge Julio López : A un mes de haber sido visto por última vez en La Plata

    OpenAIRE

    López, Jorge Julio; Vénere, Virginia; Cardoso, Miriam; Toschi, Damián; Gil Lavedra, Ricardo; Bergman, Miriam; Yanzón, Rodolfo; Derotier de Cobacho, Sara; Eloy, Nilda; Mosquera, Alejandro; Ragendorfer, Alejandro; Vedio, Marta

    2006-01-01

    Con motivo de cumplirse el primer mes de la búsqueda y reclamo de aparición de Jorge Julio López, se emite un programa especial del ciclo Por la radio, programa periodístico de la segunda mañana de Radio Universidad, conducido por Virginia Vénere, Damián Toschi y Miriam Cardoso, con producción periodística de Virginia Ilariucci. Se realizan entrevistas y se reproducen testimonios en torno a la desaparición del testigo del juicio por crímenes de lesa humanidad contra el ex jefe de la Policía B...

  5. Answer of the cucumber to a variable handling of the catering

    Directory of Open Access Journals (Sweden)

    Mario Zamora Pérez

    2017-10-01

    Full Text Available The present work was developed in areas of the organoponic of the Basic Unit of Cooperative Production “Marcial Jiménez” belonging to the Sugar Company “Enidio Díaz Machado” located in the municipality of Campechuela, county Granma, the sidebar of the experiment you executes October 25 the 2011 with the objective of evaluating the answer of the cultivation of the cucumber (Cucumis sativus L. to a variable supply of watering in those that the Tropical commercial variety SS-5 was used. The experiment settled down in stonemasons of 25 m of long; 1.20 m of wide; 0.30 m of effective basis and 0.5 m of corridors. A design of blocks was used at random with three your reply and four treatments in each experiment. The utilized basis consisted on a floor mixture brown Fersialitico (70 % and organic matter (phlegm and worm humus to 30 %. The treatments consisted on applying reductions to the watering norm indicated by the technical instructive (100, 75, 50 and 25 % in the different stages of the cultivation (of 0-10, 10-40, 40-60 and 60-80 days after the germination. Variable phonological was evaluated, vegetative and reproductive of the variety. The results demonstrate that these valued indicators decrease as a deficit hedrick is believed to the plants due to the decreases of the watering norm.

  6. Verifying the geographic origin of mahogany (Swietenia macrophylla King) with DNA-fingerprints.

    Science.gov (United States)

    Degen, B; Ward, S E; Lemes, M R; Navarro, C; Cavers, S; Sebbenn, A M

    2013-01-01

    Illegal logging is one of the main causes of ongoing worldwide deforestation and needs to be eradicated. The trade in illegal timber and wood products creates market disadvantages for products from sustainable forestry. Although various measures have been established to counter illegal logging and the subsequent trade, there is a lack of practical mechanisms for identifying the origin of timber and wood products. In this study, six nuclear microsatellites were used to generate DNA fingerprints for a genetic reference database characterising the populations of origin of a large set of mahogany (Swietenia macrophylla King, Meliaceae) samples. For the database, leaves and/or cambium from 1971 mahogany trees sampled in 31 stands from Mexico to Bolivia were genotyped. A total of 145 different alleles were found, showing strong genetic differentiation (δ(Gregorious)=0.52, F(ST)=0.18, G(ST(Hedrick))=0.65) and clear correlation between genetic and spatial distances among stands (r=0.82, P<0.05). We used the genetic reference database and Bayesian assignment testing to determine the geographic origins of two sets of mahogany wood samples, based on their multilocus genotypes. In both cases the wood samples were assigned to the correct country of origin. We discuss the overall applicability of this methodology to tropical timber trading. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  7. Mental health and professional help-seeking among college students with disabilities.

    Science.gov (United States)

    Coduti, Wendy A; Hayes, Jeffrey A; Locke, Benjamin D; Youn, Soo Jeong

    2016-08-01

    Research has demonstrated that providing appropriate supports and services on campus can improve both mental health and academic outcomes for students with disabilities (Emerson, Honey, Madden, & Llewellyn, 2009; Stumbo, Martin, & Hedrick, 2009), but little is known about the specific mental health needs of this population. The purpose of this exploratory study, therefore, was to identify the mental health needs of college students with various types of disabilities. Researchers analyzed data, collected by the Center for Collegiate Mental Health, of 5,696 students with, and without, disabilities who utilized counseling services on campuses in the 2013-14 academic year. A nonclinical (students not in counseling) sample of 1,620 students with, and without, disabilities was also explored. Compared to students without disabilities, students with disabilities report more anxiety and academic-related distress, as well as higher rates of suicide ideation, suicide attempts, and nonsuicidal self-injury among both students in counseling and not in counseling. Although in certain areas students with disabilities show similar levels of distress as students without disabilities, students with disabilities have higher levels of distress in areas which could impact their academic success. Self-harming tendencies are higher for students with disabilities overall, but more so for specific disability types. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  8. De miskenning van Theo van Doesburg; zijn bijdrage tot de ontwikkeling van de konkrete poëzie

    Directory of Open Access Journals (Sweden)

    J. van der Elst

    1987-05-01

    Full Text Available More literary critics outside Belgium and the Netherlands have written about Theo van Doesburg than from inside these countries. The first important monograph on him appeared in English - Theo van Doesburg - Propagandist and Practitioner of the Avant-Garde, 1909-1923, by Hannah Hedrick. Van Doesburg’s poetry developed in the direction of concrete poetry - the type of poetry in which the spatial, acoustic and visual characteristics of language are maximally utilized towards the creation of the poem. Word as sound and as image is foregrounded in concrete poetry, while the imaging of persons and subjective experience is eliminated as far as possible. The anecdotal or the epic component of the concrete poem is minimal and the language of this sort of poem has been reduced to the minimum. In the spirit of the theory of concrete poetry Van Doesburg advocates the liberation of art from all the commitments imposed upon it. That with which Van Doesburg began was continued by other poets, especially in Germanic literature by poets of the so-called neo-realism.

  9. Spatial structure of the meroplankton community along a Patagonian fjord - The role of changing freshwater inputs

    Science.gov (United States)

    Meerhoff, Erika; Tapia, Fabián J.; Castro, Leonardo R.

    2014-12-01

    Freshwater inputs are major drivers of circulation, hydrographic structure, and productivity patterns along estuarine systems. We assessed the degree to which meroplankton community structure in the Baker/Martinez fjord complex (Chilean Patagonia, 47.5°S) responds to spatial and temporal changes in hydrographic conditions driven by seasonal changes in Baker river outflow. Zooplankton and hydrographic measurements were conducted along the fjord in early spring (October) and late summer (February), when river outflow was minimal and maximal, respectively. Major meroplankton groups found on these surveys were larval barnacles, crabs, bivalves and gastropods. There was a clear change in community structure between October and February, explained by a switch in the numerically dominant group from barnacle to bivalve larvae. This change in community structure was related to changes in hydrographic structure along the fjord, which are mainly associated with seasonal changes in the Baker river outflow. A variance partition analysis showed no significant spatial trend that could account for the variation in meroplankton along the Martinez channel, whereas temporal variability and environmental variables accounted for 36.6% and 27.6% of the variance, respectively. When comparing meroplankton among the Baker and Martinez channels in October, changes in environmental variables explained 44.9% of total variance, whereas spatial variability accounted for 23.5%. Early and late-stage barnacle larvae (i.e. nauplii and cyprids) were more abundant in water with lower temperature, and higher dissolved oxygen and chlorophyll-a concentration, whereas bivalve larvae were more strongly associated to warmer waters. The seasonal shift in numerical dominance, from barnacle larvae in early spring to bivalve larvae in late summer, suggests that reproduction of these groups is triggered by substantially different sets of conditions, both in terms of hydrography and food availability. The

  10. An Integrated Procedure for the Structural Design of a Composite Rotor-Hydrofoil of a Water Current Turbine (WCT)

    Science.gov (United States)

    Oller Aramayo, S. A.; Nallim, L. G.; Oller, S.

    2013-12-01

    This paper shows an integrated structural design optimization of a composite rotor-hydrofoil of a water current turbine by means the finite elements method (FEM), using a Serial/Parallel mixing theory (Rastellini et al. Comput. Struct. 86:879-896, 2008, Martinez et al., 2007, Martinez and Oller Arch. Comput. Methods. 16(4):357-397, 2009, Martinez et al. Compos. Part B Eng. 42(2011):134-144, 2010) coupled with a fluid-dynamic formulation and multi-objective optimization algorithm (Gen and Cheng 1997, Lee et al. Compos. Struct. 99:181-192, 2013, Lee et al. Compos. Struct. 94(3):1087-1096, 2012). The composite hydrofoil of the turbine rotor has been design using a reinforced laminate composites, taking into account the optimization of the carbon fiber orientation to obtain the maximum strength and lower rotational-inertia. Also, these results have been compared with a steel hydrofoil remarking the different performance on both structures. The mechanical and geometrical parameters involved in the design of this fiber-reinforced composite material are the fiber orientation, number of layers, stacking sequence and laminate thickness. Water pressure in the rotor of the turbine is obtained from a coupled fluid-dynamic simulation (CFD), whose detail can be found in the reference Oller et al. (2012). The main purpose of this paper is to achieve a very low inertia rotor minimizing the start-stop effect, because it is applied in axial water flow turbine currently in design by the authors, in which is important to take the maximum advantage of the kinetic energy. The FEM simulation codes are engineered by CIMNE (International Center for Numerical Method in Engineering, Barcelona, Spain), COMPack for the solids problem application, KRATOS for fluid dynamic application and RMOP for the structural optimization. To validate the procedure here presented, many turbine rotors made of composite materials are analyzed and three of them are compared with the steel one.

  11. (Un)Disciplined futures: Women of color feminism as a disruptive to white affect studies.

    Science.gov (United States)

    Garcia-Rojas, Claudia

    2017-07-03

    The aim of this article is to demonstrate how women of color feminism predates and disrupts dominant dialogues in the field of White affect studies. I introduce the concept of White affect studies as an arena of inquiry that draws from Western-European theories and literatures and architects a sociopolitical structure of affect that positions White affects as universal. Scholars contributing to the field of White affect studies posit theories of affect, embodiment, subjectivity, phenomenology, violence, war, and more, while disregarding the theoretical contributions made by women of color feminism in thinking through these notions and social issues. This is done by engaging in a citational practice that results in an epistemic erasure of women of color feminist thought. The voices of women of color feminists are thus disqualified, and their theoretical contributions are not acknowledged as significant or relevant in conceptualizing affect, affective economies, and the social. By turning to the writings of women of color feminists, I demonstrate how their theories on embodiment, subjectivity, and social structures predate the institutionalization of White affect studies. Feminists of color from the past and present have and continue to theorize through a language of self their experiences as subjects embedded within matrices of violence, power, and pleasure. Lorde, Martinez, and Chinchilla write about the ways in which lesbian and queer women of color institute different affects that counter dominant structures of emotion, systems of power, and heterosexual modes of being. In developing conceptual methodologies, Lorde, Martinez, and Chinchilla are able to weave into the dominant discursive logic a language of self that both introduces new queer subjectivities, while reinterpreting existing forms of thought, thereby contesting mainstream economies of White affects and White affect studies. It is through a language of self that Lorde, Martinez, and Chinchilla develop

  12. Leptogenesis and reheating in complex hybrid inflation

    International Nuclear Information System (INIS)

    Martinez-Prieto, Carlos; Delepine, David; Urena-Lopez, L. Arturo

    2010-01-01

    We study the transformation into a baryon asymmetry of a charge initially stored in a complex (waterfall) scalar field at the end of a hybrid inflation phase as described by Delepine, Martinez, and Urena-Lopez [Phys. Rev. Lett. 98, 161302 (2007)]. The waterfall field is coupled to right-handed neutrinos, and is also responsible for their Majorana masses. The charge is finally transferred to the leptons of the standard model through the decay of the right-handed neutrinos without introducing new CP violating interactions. Other needed processes, like the decay of the inflaton field and the reheating of the Universe, are also discussed in detail.

  13. Holographic superconductor in the analytic hairy black hole

    International Nuclear Information System (INIS)

    Myung, Yun Soo; Park, Chanyong

    2011-01-01

    We study the charged black hole of hyperbolic horizon with scalar hair (charged Martinez-Troncoso-Zanelli: CMTZ black hole) as a model of analytic hairy black hole for holographic superconductor. For this purpose, we investigate the second order phase transition between CMTZ and hyperbolic Reissner-Nordstroem-AdS (HRNAdS) black holes. However, this transition unlikely occurs. As an analytic treatment for holographic superconductor, we develop superconductor in the bulk and superfluidity on the boundary using the CMTZ black hole below the critical temperature. The presence of charge destroys the condensates around the zero temperature, which is in accord with the thermodynamic analysis of the CMTZ black hole.

  14. Reviews of recent publications

    Directory of Open Access Journals (Sweden)

    2005-01-01

    Full Text Available Chanan, Michael. Cuban Cinema David William Foster Izenberg, Gerald N. Modernism and Masculinity: Mann, Wedekind, Kandisnky through World War I. Aaron J. Cohen Jonsson, Stefan. Subject Without Nation: Robert Musil and the History of Modern Identity. Post-Contemporary Interventions. Albrecht Classen Kaiser, David Aram. Romanticism, Aesthetics and Nationalism. Cambridge Studies in Romanticism 34. Catherine Grimm Lopez de Martinez, Adelaida and Harriet Turner. The Cambridge Companion to the Spanish Novel: From 1600 to the Present. Toni Dorca McCulloh, Mark R. Understanding W.G. Sebald. Peter C. Pfeiffer Peterson, Dale E. Up From Bondage: The Literatures of Russian and African American Soul. Kathleen M. Ahren

  15. Microstructure and Thermal Expansion Properties of Ostrich Eggshell

    Science.gov (United States)

    2002-04-01

    A.Rodriguez-Hernindez, E. Villarreal4, A. Martinez, M.V. Garcia-GardufiolŖ, V.A. Basiuk 3ř, L. Bucio and E. Orozco Instituto de Fisica UNAM, Apdo. Postal 20...Ku, Yokohama 240-8501.41nstituto de Investigaciones en Materiales, UNAM, 04510 Mexico D.F. Mexico ABSTRACT Textures of calcite crystals from ostrich...364, 01000 Mexico D.F., Mexico ’Facultad de Ciencias UNAM, 04510 Mexico D.F. Mexico 2 Div. de Posgr. e Invest., Facultad de Odontologia UNAM, 04510

  16. Handbook of sensor networks compact wireless and wired sensing systems

    CERN Document Server

    Ilyas, Mohammad

    2004-01-01

    INTRODUCTION Opportunities and Challenges in Wireless Sensor Networks, M. Haenggi, Next Generation Technologies to Enable Sensor Networks, J. I.  Goodman, A. I. Reuther, and D. R. Martinez Sensor Networks Management, L. B. Ruiz, J. M. Nogueira, and A. A. F. Loureiro Models for Programmability in Sensor Networks, A. Boulis Miniaturizing Sensor Networks with MEMS, Brett Warneke A Taxonomy of Routing Techniques in Wireless Sensor Networks, J. N. Al-Karaki and A. E. Kamal Artificial Perceptual Systems, A. Loutfi, M. Lindquist, and P. Wide APPLICATIONS Sensor Network Architecture and Appl

  17. Developing a Beta-Lapachone Prodrug for Therapy Against NQ01-Overexpressing Breast Cancers

    Science.gov (United States)

    2006-03-01

    Affairs Medical Center, Cleveland, Ohio; 8Departa- mento de Qui¤mica Orga¤ nica, Facultad de Ciencias Exactas y Naturales , Universidad de Buenos Aires...W81XWH-05-1-0248 8 Marin A, Lopez de Cerain A, Hamilton E, Lewis AD, Martinez-Penuela JM et al. (1997) DT-diaphorase and cytochrome B5 reductase...costs of publication of this article were defrayed in part by the payment of page charges.This article must therefore be hereby marked advertisement

  18. 2002 Industry Studies: News Media

    Science.gov (United States)

    2002-01-01

    USAF CAPT John W. Coleman II, USN Reserve Col Christos Dellas , Greek Army Col Tim Fletcher USAF Lt Col Tim Malinski USAF Lt Col Deb Martinez USAF Ms...Majority Support Government Restrictions on War Coverage,” Washington Post, 29 November 2001, Sec. C, p.1. 54 Lucia Moses, “E&P Survey: Circ Bump was...Afghan War,” The Washington Post, 7 December 2001, Sec. A, p. 43. Moses, Lucia , “E&P Survey: Circ Bump was Modest,” Editor & Publisher, 22 April 2002

  19. Time Transfer from Combined Analysis of GPS and TWSTFT Data

    Science.gov (United States)

    2008-12-01

    2005/429 and BEFPI/2007/040 of the Consellería de Empresa , Universidad y Ciencia of the Generalitat Valenciana. The authors also acknowledge the time...and Z. Jiang2 1University of Alicante, Spain, E-mail: carmen.martinez@ua.es 2Bureau International des Poids et Mesures, France, E-mail: zjiang...failing to comply with a collection of information if it does not display a currently valid OMB control number. 1. REPORT DATE 01 DEC 2008 2. REPORT

  20. Inventário de burnout de Maslach para estudantes portugueses

    OpenAIRE

    Maroco, João; Tecedeiro, Miguel Moreira Vaz

    2009-01-01

    O Maslach Burnout Inventory – Student Survey adaptado por Schaufeli, Martinez et al., 2002 a partir do Maslach Burnout Inventory – General Survey foi traduzido e adaptado para a lingua portuguesa.A avaliação das qualidades psicométricas da Escala de Burnout para Estudantes foi feita numa amostra de 654 estudantes universitários. A Escala de Burnout para Estudantes revelou uma adequada validade factorial e fiabilidade na amostra sob estudo revelando-se um instrumento sensível, ...

  1. “Todo lo que sigue es sencillamente estupendo”. Escritoras en las cartas de Ezequiel Martínez Estrada a Victoria Ocampo

    Directory of Open Access Journals (Sweden)

    Tania Diz

    2016-11-01

    Full Text Available While Ezequiel Martínez Estrada writes Marta Riquelme, between his fiction and essays, and Victoria Ocampo begins to write her memories; it arises from both an emotional and intellectual relationship through letters along more than 15 years since the late '40s and until the death of Martinez Estrada in 1964. This article will discuss much of those letters with the intended to show that one of the central axes of the epistolary is the construction by Martínez Estrada, his interlocutor in a character: writer women who acquire multiple identities including Marta Riquelme looks.

  2. Function of the Alpha6 in Breast Carcinoma

    Science.gov (United States)

    2000-10-01

    CeIll 91:949-9610. tastases of a matliglntnt humsan breast cancer in nud,~e mtice. Mon0. Genec Thee. Shi.ý Y., I.MN. Glynn. LIJ. G nilbert. T.G. Cotter...Bellacosa. M. Nieborossska-Skorska, M. Mikcjsski. R. Martinez, as it cell survival factor. Mod. Biol. CeIll 4:953-96). 3. K. Chcsi. R. Trot tc. P...small, fragmented lamellae that were devoid of Glass coverslips were coated overnight at 4’C with collagen 1 (50 l.g/ml: membrane ruffles (Fig. 1 B

  3. A comparison of Mg/Ca ratios in Globigerinoides ruber (white): sensu stricto versus a mixture of genotypes

    Digital Repository Service at National Institute of Oceanography (India)

    Naik, S.S.

    at the University of Southampton, UK, using G. ruber, sensu stricto only. Cleaned samples were dissolved in 100-300 µl 0.5M HNO3. Mg/Ca ratios were analysed on a Thermo Finnigan Element 2 ICP-MS. Long term precision for Mg/Ca is 3% (2σ) based on repeat.... Acknowledgements: I thank Jimin Yu of LDEO and Miguel Martinez-Boti of the University of Southampton for the analytical help. This work was funded by the INDOUSSTF fellowship and a DST Fast Track Project to SN. This is National Institute of Oceanography...

  4. Wood-polymer composites obtained by gamma radiation

    International Nuclear Information System (INIS)

    Gago, Javier; Lopez, Alcides; Rodriguez, Juan; Universidad Nacional de Ingenieria, Lima; Acevedo, Moises; Santiago, Julio; Universidad Nacional Mayor de San Marcos, Lima

    2006-01-01

    It has been prepared composites materials by means of monomer penetration in pores of wood samples and later curing by means of gamma irradiation. The studied species were Hura crepitans L. (catahua), Aniba puchury-minor (C. Martinez) (mohena amarilla), and Calycophyllum spruceanum (Benth.) (capirona). These new materials exhibit smaller water absorption and better mechanical properties in comparison with native wood. The test tubes of catahua treated with the styrene-polyester mixture absorb only up to 10% humidity compared to the native species whereas its hardness is increased in a 100%. (author)

  5. Dissecting and Targeting Latent Metastasis

    Science.gov (United States)

    2013-09-01

    J.A., Grijota-Martinez, C., Lakoma, J., Baars, S., Garcia - Alonso , L., and Cabedo, H. (2012). L1CAM binds ErbB receptors through Ig-like domains...at converting plasminogen into plasmin (Figure S2K). Neurons are known to produce plasminogen for neurite and synapse formation (Gutierrez- Fernandez ...building a framework. Cell 127, 679-695. Gutierrez- Fernandez , A., Gingles, N.A., Bai, H., Castellino, F.J., Parmer, R.J., and Miles, L.A. (2009

  6. El mosaico del centauro, un eco de la antigüedad clásica en el Museo de Bellas Artes de Valencia

    OpenAIRE

    Alejos Morán, Asunción

    1992-01-01

    EN EL MUSEO DE BELLAS ARTES DE VALENCIA SE CONSERVA UN MOSAICO (57 X 59 CM.) EN EL QUE SE REPRESENTA LA LUCHA ENTRE UN CENTAURO Y UN TIGRE. PROCEDE DEL LEGADO QUE DON FRANCISCO MARTINEZ BLANCH HIZO A LA REAL ACADEMIA DE SAN CARLOS DE VALENCIA EN 1835. SE TRATA DE UNA IMITACION RENACENTISTA DE UN PAVIMENTO MOSAICO DE LA VILLA DE ADRIANO EN TIVOLI, ACTUALMENTE EN EL STAATLICHE MUSEUM DE BERLIN, SI BIEN LA VERSION DE VALENCIA ELIMINA TRES DE LAS FIGURAS DEL ORIGINAL. LA MITOLOGIA GRECORROMANA PR...

  7. Someone Has Led This Child To Believe

    OpenAIRE

    Louise, Regina

    2015-01-01

    ABSTRACTSOMEONE HAS LED THIS CHILD TO BELIEVE is a true story and continuation of the best-selling memoir Somebody’s Someone. After 12 year-old Regina Louise, tired of being beaten, battles and escapes an illegal guardian; she jumps from a two-story window and runs to a local police station where she is taken into custody, locked in a holding cell, and delivered to the Edgar Children’s Shelter, in Martinez California. Regina is closed off about her parents, her past…until she meets Jeanne Ke...

  8. Strategies for Closing the ITRS Funding Gap

    Science.gov (United States)

    2008-08-01

    The semiconductor industry needs to find creative ways to close the $1.1 – 1.5B research gap , first noted in 2003, between the funding being...2008 2. REPORT TYPE 3. DATES COVERED 00-00-2008 to 00-00-2008 4. TITLE AND SUBTITLE Strategies for Closing the ITRS Funding Gap 5a. CONTRACT...Rev. 8-98) Prescribed by ANSI Std Z39-18 STRATEGIES FOR CLOSING THE ITRS FUNDING GAP # Yaw S. Obeng, Stephen Knight, and Joaquin V. Martinez de

  9. A new species of Havelockia Pearson, 1903 from the Argentine Sea (Holothuroidea: Dendrochirotida: Sclerodactylidae).

    Science.gov (United States)

    Martinez, Mariano I; Thandar, Ahmed S; Penchaszadeh, Pablo E

    2013-02-04

    Havelockia pegi sp. nov., is here described from shallow waters of the Argentine Sea. This new species is distinctive in the purple colouration of its tentacles, scarcity of body wall ossicles and the presence of rosette-shaped ossicles in both the introvert and the tentacles. It is not closely related to any of its congenors. This is the first record of a true sclerodactylid from Argentina. Thandarum hernandezi Martinez & Brogger, 2012, described in the family Sclerodactylidae, is now classified in the family Sclerothyonidae.

  10. M. Pirgerou on D. Izzo and C. Martinez’s Revisionary Interventions into Henry James

    Directory of Open Access Journals (Sweden)

    2009-07-01

    Full Text Available Donatella Izzo and Carlo Martinez. Revisionary Interventions Into Henry James. Eds. Napoli, 2008. Revisionary Interventions into Henry James is a compilation of a series of papers presented at a colloquium which took place at Università Orientale in Naples, Italy, on October 27, 2006. In her introduction to the volume, Donatella Izzo acknowledges the “rather blatant plagiarism” (7 which lent the book its title.  The borrowing, of course, refers to Donald Pease’s landmark Revisionary Interve...

  11. Street vending and informal economy: Survey data from Cali, Colombia.

    Science.gov (United States)

    Martinez, Lina M; Estrada, Daniela

    2017-10-01

    This data brief describes data collected in Cali, Colombia about the economic dynamic and socioeconomic conditions of street vendors in the city. The study was conducted between 2014 and 2016 in two populated sites in terms of formal and informal commerce in the city. We present the methodology followed in the study, location of street vending sites and type of data collected to approximate to the economic dimension of street vending. Data collected contains information about sociodemographic characteristics, life satisfaction, business operation and characteristics, income and expenses, official license for operation. This information is linked to the publication (Martinez et al., 2017) [1].

  12. Latin America Report

    Science.gov (United States)

    1987-04-09

    Bonilla , of the Labor Affairs section of the CST, says that the reasons for the absenteeism in these 59 enterprises during the first half of the year...absences. Bonilla indicated that in that half of 1986, there were 28,878 unjustified absences in these 59 enterprises studied alone, of which total the...labor day was only utilized to the extent of 72, 61, 64 or 69 percent. Damaso Vargas and Pablo Martinez, CST leaders in Region III, say that there are

  13. Quasilower subdifferentiability and quasiconvex duality gap

    International Nuclear Information System (INIS)

    Pham Hong Quang.

    1992-07-01

    In this note we introduce a notion of quasilower subdifferentiability which is an extension of that of lower subdifferentiability due to Plastria F. by using the concept of ε-subdifferential in convex analysis. We obtain that at a given point a function is quasilower subdifferentiable if and only if the values of this function and its second quasiconvex conjugate coincide. It is proved that the second quasiconvex conjugate is a best approximation in the class of second h α -conjugate defined by Martinez-Legaz and Romano-Rodriguez S. An application of the notion of quasilower subdifferentiability for the facial programming problems is given. (author). 10 refs

  14. Particle Swarm Optimization algorithms for geophysical inversion, practical hints

    Science.gov (United States)

    Garcia Gonzalo, E.; Fernandez Martinez, J.; Fernandez Alvarez, J.; Kuzma, H.; Menendez Perez, C.

    2008-12-01

    PSO is a stochastic optimization technique that has been successfully used in many different engineering fields. PSO algorithm can be physically interpreted as a stochastic damped mass-spring system (Fernandez Martinez and Garcia Gonzalo 2008). Based on this analogy we present a whole family of PSO algorithms and their respective first order and second order stability regions. Their performance is also checked using synthetic functions (Rosenbrock and Griewank) showing a degree of ill-posedness similar to that found in many geophysical inverse problems. Finally, we present the application of these algorithms to the analysis of a Vertical Electrical Sounding inverse problem associated to a seawater intrusion in a coastal aquifer in South Spain. We analyze the role of PSO parameters (inertia, local and global accelerations and discretization step), both in convergence curves and in the a posteriori sampling of the depth of an intrusion. Comparison is made with binary genetic algorithms and simulated annealing. As result of this analysis, practical hints are given to select the correct algorithm and to tune the corresponding PSO parameters. Fernandez Martinez, J.L., Garcia Gonzalo, E., 2008a. The generalized PSO: a new door to PSO evolution. Journal of Artificial Evolution and Applications. DOI:10.1155/2008/861275.

  15. Metal temperature monitoring in corrosive gases at high temperature and high thermal flows; Monitoreo de temperaturas de metal en gases corrosivos a alta temperatura y altos flujos termicos

    Energy Technology Data Exchange (ETDEWEB)

    Huerta Espino, Mario; Martinez Flores, Marco Antonio; Martinez Villafane, Alberto; Porcayo Calderon, Jesus; Gomez Guzman, Roberto; Reyes Cervantes, Fernando [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

    1990-12-31

    The direct measurement of metal temperatures during operation in superheater, reheater, and water wall tubes in zones exposed to high thermal flows is of great interest for the operation and analysis of the correct functioning of a steam generator. The operation temperature measurement of these zones differs very much of the monitored temperature in headers in the dead chamber, since the temperature measured in this zone is the steam temperature that does not reflect the one detected in the gas zone. For this reason, the thermocouples implant in gas zones will detect the real metal temperature and the incidence that some operation variables might have on it (Martinez et al., (1990). [Espanol] La medicion directa de temperaturas de metal durante operacion en tubos de sobrecalentador, recalentador y pared de agua en zonas expuestas a altos flujos termicos es de gran interes para la operacion y analisis del buen funcionamiento de un generador de vapor. La medicion de la temperatura de operacion de estas zonas, difiere mucho de la temperatura monitoreada en cabezales en zona de camara muerta, ya que la temperatura registrada en esta zona es la de vapor que no es un reflejo de la detectada en zona de gases. Por esta razon, la implantacion de termopares en zona de gases detectara la temperatura de metal real y la incidencia que algunas variables de operacion tengan sobre esta (Martinez et al., 1990).

  16. Metal temperature monitoring in corrosive gases at high temperature and high thermal flows; Monitoreo de temperaturas de metal en gases corrosivos a alta temperatura y altos flujos termicos

    Energy Technology Data Exchange (ETDEWEB)

    Huerta Espino, Mario; Martinez Flores, Marco Antonio; Martinez Villafane, Alberto; Porcayo Calderon, Jesus; Gomez Guzman, Roberto; Reyes Cervantes, Fernando [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

    1991-12-31

    The direct measurement of metal temperatures during operation in superheater, reheater, and water wall tubes in zones exposed to high thermal flows is of great interest for the operation and analysis of the correct functioning of a steam generator. The operation temperature measurement of these zones differs very much of the monitored temperature in headers in the dead chamber, since the temperature measured in this zone is the steam temperature that does not reflect the one detected in the gas zone. For this reason, the thermocouples implant in gas zones will detect the real metal temperature and the incidence that some operation variables might have on it (Martinez et al., (1990). [Espanol] La medicion directa de temperaturas de metal durante operacion en tubos de sobrecalentador, recalentador y pared de agua en zonas expuestas a altos flujos termicos es de gran interes para la operacion y analisis del buen funcionamiento de un generador de vapor. La medicion de la temperatura de operacion de estas zonas, difiere mucho de la temperatura monitoreada en cabezales en zona de camara muerta, ya que la temperatura registrada en esta zona es la de vapor que no es un reflejo de la detectada en zona de gases. Por esta razon, la implantacion de termopares en zona de gases detectara la temperatura de metal real y la incidencia que algunas variables de operacion tengan sobre esta (Martinez et al., 1990).

  17. The future of bioenergy; Die Zukunft der Bioenergie

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2015-07-01

    This volume contains the following five contributions: 1. The impact of the governmental biogas production on agricultural rents in Germany. An econometric study (Hendrik Garvert); 2. Biogas as price drivers on the land and rental market? An Empirical Analysis (Uwe Latacz-Lohmann); 3. Analysis of comparative advantage of bioenergy in electricity and heat production. Greenhouse gas abatement and mitigation costs in Brandenburg (Lukas Scholz); 4. Flexibility potential of biogas and biomethane CHP in the investment portfolio (Matthias Edel); 5. Legal possibilities and limitations of a reform of the system for the promotion of bioenergy (Jose Martinez). [German] Dieser Band enthaelt folgende fuenf Themenbeitraege: 1. Die Auswirkungen der staatlichen Biogasfoerderung auf landwirtschaftliche Pachtpreise in Deutschland. Eine oekonometrische Untersuchung (Hendrik Garvert); 2. Biogas als Preistreiber am Bodenmarkt und Pachtmarkt? Eine empirische Analyse (Uwe Latacz-Lohmann); 3. Analyse komparativer Kostenvorteile von Bioenergielinien in der Strom- und Waermeproduktion Treibhausgasvermeidung und Vermeidungskosten in Brandenburg (Lukas Scholz); 4. Flexibilisierungspotenzial von Biogas- und Biomethan-BHKWs im Anlagenbestand (Matthias Edel); 5. Rechtliche Moeglichkeiten und Grenzen einer Reform des Systems zur Foerderung der Bioenergie (Jose Martinez).

  18. Simultaneous recordings of ocular microtremor and microsaccades with a piezoelectric sensor and a video-oculography system

    Directory of Open Access Journals (Sweden)

    Michael B. McCamy

    2013-02-01

    Full Text Available Our eyes are in continuous motion. Even when we attempt to fix our gaze, we produce so called “fixational eye movements”, which include microsaccades, drift, and ocular microtremor (OMT. Microsaccades, the largest and fastest type of fixational eye movement, shift the retinal image from several dozen to several hundred photoreceptors and have equivalent physical characteristics to saccades, only on a smaller scale (Martinez-Conde, Otero-Millan & Macknik, 2013. OMT occurs simultaneously with drift and is the smallest of the fixational eye movements (∼1 photoreceptor width, >0.5 arcmin, with dominant frequencies ranging from 70 Hz to 103 Hz (Martinez-Conde, Macknik & Hubel, 2004. Due to OMT’s small amplitude and high frequency, the most accurate and stringent way to record it is the piezoelectric transduction method. Thus, OMT studies are far rarer than those focusing on microsaccades or drift. Here we conducted simultaneous recordings of OMT and microsaccades with a piezoelectric device and a commercial infrared video tracking system. We set out to determine whether OMT could help to restore perceptually faded targets during attempted fixation, and we also wondered whether the piezoelectric sensor could affect the characteristics of microsaccades. Our results showed that microsaccades, but not OMT, counteracted perceptual fading. We moreover found that the piezoelectric sensor affected microsaccades in a complex way, and that the oculomotor system adjusted to the stress brought on by the sensor by adjusting the magnitudes of microsaccades.

  19. Teaching students in place: the languages of third space learning

    Science.gov (United States)

    Morawski, Cynthia M.

    2017-09-01

    With a perceptive eye cast on geoscience pedagogy for students labeled as disabled, Martinez-Álvarez makes important contributions to the existing conversation on placed-based learning. It is in our local backyards, from the corner basketball court, to the mud bank of a city lake, to the adjacent field where rocky outcrops spill down to a forgotten farmer's field, that we find rich working material for connecting self and community, moving students' out-of-school experiences that feature their cultural and linguistic knowledge, from misconceptions to "alternative conceptions." Informed by her insights regarding the learning of students whose literacy does not match conventional classroom practice, geoscience learning in the place of third space can act as a model of meaning making across the entire curriculum. In the pages that follow, I transact, both aesthetically and efferently, with Martinez-Álvarez's text as she presents her research on special ways of learning in placed-based geoscience explorations with bilingual children experiencing disabilities.

  20. Evaluating Water Quality in a Suburban Environment

    Science.gov (United States)

    Thomas, S. M.; Garza, N.

    2008-12-01

    A water quality analysis and modeling study is currently being conducted on the Martinez Creek, a small catchment within Cibolo watershed, a sub-basin of the San Antonio River, Texas. Several other major creeks, such as Salatrillo, Escondido, and Woman Hollering merge with Martinez Creek. Land use and land cover analysis shows that the major portion of the watershed is dominated by residential development with average impervious cover percentage of approximately 40% along with a some of agricultural areas and brushlands. This catchment is characterized by the presence of three small wastewater treatment plants. Previous site visits and sampling of water quality indicate the presence of algae and fecal coliform bacteria at levels well above state standards at several locations in the catchment throughout the year. Due to the presence of livestock, residential development and wastewater treatment plants, a comprehensive understanding of water quality is important to evaluate the sources and find means to control pollution. As part of the study, a spatial and temporal water quality analyses of conventional parameters as well as emerging contaminants, such as veterinary pharmaceuticals and microbial pathogens is being conducted to identify critical locations and sources. Additionally, the Hydrologic Simulation Program FORTRAN (HSPF) will be used to identify best management practices that can be incorporated given the projected growth and development and feasibility.

  1. Allelic diversity in populations of Solanum lycocarpum A. St.-Hil (Solanaceae in a protected area and a disturbed environment Diversidade alélica em populações de Solanum lycocarpum A. St.-Hil (Solanaceae em Unidade de Conservação e em ambiente sob influência antrópica

    Directory of Open Access Journals (Sweden)

    Tânia Maria de Moura

    2011-12-01

    Full Text Available This study aimed to compare the genetic diversity of populations of Solanum lycocarpum A.St.-Hil between natural and human disturbed environments, with the assumption that protected areas have greater genetic diversity than disturbed areas. For this study, two populations were sampled in Goiás State, Brazil. One was located in a conservation unit, Serra de Caldas Novas State Park, in the Caldas Novas municipality. The other was located in a pasture area in the municipality of Morrinhos. The two populations are 41 km apart. We sampled 60 individuals from each population, which were genotyped with five microsatellite loci (SSR. The highest number of alleles was recorded in the population of the conservation unit, where we found 11 exclusive and five rare alleles. In the disturbed area, we recorded only three exclusive alleles and one rare allele. Although we did not observe significant inbreeding in these populations, genetic divergence between them was high (G ST (Hedrick=0.147 =0.147 for a species with long distance seed dispersal. The results corroborate the hypothesis that the population in the less disturbed area harbors greater allelic diversity. They also confirm the effectiveness of using protected areas to preserve the genetic diversity of the species.O presente trabalho teve por objetivo comparar a diversidade genética em populações de Solanum lycocarpum A.St.-Hil, em ambientes naturais e antropizados, sob a hipótese de que Unidades de Conservação abrigam maior diversidade genética que áreas antropizadas. Para isso foram estudadas duas populações da espécie, uma situada em uma Unidade de Conservação, o Parque Estadual da Serra de Caldas Novas (PESCAN em Caldas Novas/GO e outra situada em uma área de pastagem no município de Morrinhos-GO. As populações distanciam-se em 41 km. Foram amostrados 60 indivíduos de cada população e os mesmos foram genotipados com cinco locos microssatélites (SSR. Pode-se registrar a maior

  2. Second-hand smoke in Italy.

    Science.gov (United States)

    Gallus, S

    2015-12-01

    Second-hand smoke (SHS) has been classified as carcinogenic to humans by the International Agency for Research on Cancer (IARC) of the World Health Organization (WHO) [IARC, 2004]. Of the 5.7 million deaths attributable each year to tobacco smoking, more than 600,000 (i.e., around 1% of all deaths worldwide) refer to subjects who never smoked and that prematurely die due to their lifetime exposure to SHS [WHO, 2012]. Italy has been one of the pioneering countries - and the first large country worldwide - to enact a comprehensive smoke-free legislation in 2005. The law, introduced in order to reduce SHS exposure, banned smoking in indoor public places, including restaurants and bars, and in all workplaces [Gallus et al., 2006]. This legislation has had an undisputed success from a public health perspective: it was widely supported and strongly observed, restaurant and bar owners did not experience any dreaded decline in their business, and tobacco smoking (and its detrimental health effects) substantially decreased [Gallus et al., 2006; Gorini et al., 2007]. More importantly, the regulation has been effective in dramatically reducing SHS exposure [Gorini et al., 2007; Martinez-Sanchez et al., 2012]. Most high- income countries followed Italy in the adoption of similar comprehensive smoking ban legislations over the last decade [IARC, 2009]. These regulations and the information campaigns conducted for their enforcement had also the effect to increase the social unacceptability of SHS and consequently the adoption of voluntary home smoking bans [Ferketich et al., 2014; Martinez-Sanchez et al., 2014]. This notwithstanding, in 2010 specific Italian subpopulations were still frequently exposed to SHS, both in public and private places. In particular, 54% of the young (i.e., age 15-24 years) were still exposed to SHS in any settings, 27% in private houses, and 33% in private cars [Martinez-Sanchez et al., 2012]. The relatively high SHS exposure in private cars is of

  3. Lightweight Double Neutron Star Found

    Science.gov (United States)

    Kohler, Susanna

    2018-02-01

    More than forty years after the first discovery of a double neutron star, we still havent found many others but a new survey is working to change that.The Hunt for PairsThe observed shift in the Hulse-Taylor binarys orbital period over time as it loses energy to gravitational-wave emission. [Weisberg Taylor, 2004]In 1974, Russell Hulse and Joseph Taylor discovered the first double neutron star: two compact objects locked in a close orbit about each other. Hulse and Taylors measurements of this binarys decaying orbit over subsequent years led to a Nobel prize and the first clear evidence of gravitational waves carrying energy and angular momentum away from massive binaries.Forty years later, we have since confirmed the existence of gravitational waves directly with the Laser Interferometer Gravitational-Wave Observatory (LIGO). Nonetheless, finding and studying pre-merger neutron-star binaries remains a top priority. Observing such systems before they merge reveals crucial information about late-stage stellar evolution, binary interactions, and the types of gravitational-wave signals we expect to find with current and future observatories.Since the Hulse-Taylor binary, weve found a total of 16 additional double neutron-star systems which represents only a tiny fraction of the more than 2,600 pulsars currently known. Recently, however, a large number of pulsar surveys are turning their eyes toward the sky, with a focus on finding more double neutron stars and at least one of them has had success.The pulse profile for PSR J1411+2551 at 327 MHz. [Martinez et al. 2017]A Low-Mass DoubleConducted with the 1,000-foot Arecibo radio telescope in Puerto Rico, the Arecibo 327 MHz Drift Pulsar Survey has enabled the recent discovery of dozens of pulsars and transients. Among them, as reported by Jose Martinez (Max Planck Institute for Radio Astronomy) and coauthors in a recent publication, is PSR J1411+2551: a new double neutron star with one of the lowest masses ever measured

  4. The power to detect recent fragmentation events using genetic differentiation methods.

    Directory of Open Access Journals (Sweden)

    Michael W Lloyd

    Full Text Available Habitat loss and fragmentation are imminent threats to biological diversity worldwide and thus are fundamental issues in conservation biology. Increased isolation alone has been implicated as a driver of negative impacts in populations associated with fragmented landscapes. Genetic monitoring and the use of measures of genetic divergence have been proposed as means to detect changes in landscape connectivity. Our goal was to evaluate the sensitivity of Wright's F st, Hedrick' G'st , Sherwin's MI, and Jost's D to recent fragmentation events across a range of population sizes and sampling regimes. We constructed an individual-based model, which used a factorial design to compare effects of varying population size, presence or absence of overlapping generations, and presence or absence of population sub-structuring. Increases in population size, overlapping generations, and population sub-structuring each reduced F st, G'st , MI, and D. The signal of fragmentation was detected within two generations for all metrics. However, the magnitude of the change in each was small in all cases, and when N e was >100 individuals it was extremely small. Multi-generational sampling and population estimates are required to differentiate the signal of background divergence from changes in Fst , G'st , MI, and D associated with fragmentation. Finally, the window during which rapid change in Fst , G'st , MI, and D between generations occurs can be small, and if missed would lead to inconclusive results. For these reasons, use of F st, G'st , MI, or D for detecting and monitoring changes in connectivity is likely to prove difficult in real-world scenarios. We advocate use of genetic monitoring only in conjunction with estimates of actual movement among patches such that one could compare current movement with the genetic signature of past movement to determine there has been a change.

  5. "It's Totally Okay to Be Sad, but Never Lose Hope": Content Analysis of Infertility-Related Videos on YouTube in Relation to Viewer Preferences.

    Science.gov (United States)

    Kelly-Hedrick, Margot; Grunberg, Paul H; Brochu, Felicia; Zelkowitz, Phyllis

    2018-05-23

    Infertility patients frequently use the internet to find fertility-related information and support from people in similar circumstances. YouTube is increasingly used as a source of health-related information and may influence health decision making. There have been no studies examining the content of infertility-related videos on YouTube. The purpose of this study was to (1) describe the content of highly viewed videos on YouTube related to infertility and (2) identify video characteristics that relate to viewer preference. Using the search term "infertility," the 80 top-viewed YouTube videos and their viewing statistics (eg, views, likes, and comments) were collected. Videos that were non-English, unrelated to infertility, or had age restrictions were excluded. Content analysis was used to examine videos, employing a coding rubric that measured the presence or absence of video codes related to purpose, tone, and demographic and fertility characteristics (eg, sex, parity, stage of fertility treatment). A total of 59 videos, with a median of 156,103 views, met the inclusion criteria and were categorized into 35 personal videos (35/59, 59%) and 24 informational-educational videos (24/59, 41%). Personal videos did not differ significantly from informational-educational videos on number of views, dislikes, subscriptions driven, or shares. However, personal videos had significantly more likes (PYouTube is a source of both technical and personal experience-based information about infertility. However, videos that include personal experiences may elicit greater viewer engagement. Positive videos and stories of treatment success may provide hope to viewers but could also create and perpetuate unrealistic expectations about the success rates of fertility treatment. ©Margot Kelly-Hedrick, Paul H Grunberg, Felicia Brochu, Phyllis Zelkowitz. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 23.05.2018.

  6. If F(ST) does not measure neutral genetic differentiation, then comparing it with Q(ST) is misleading. Or is it?

    Science.gov (United States)

    Edelaar, Pim; Björklund, Mats

    2011-05-01

    The comparison between neutral genetic differentiation (F(ST) ) and quantitative genetic differentiation (Q(ST) ) is commonly used to test for signatures of selection in population divergence. However, there is an ongoing discussion about what F(ST) actually measures, even resulting in some alternative metrics to express neutral genetic differentiation. If there is a problem with F(ST) , this could have repercussions for its comparison with Q(ST) as well. We show that as the mutation rate of the neutral marker increases, F(ST) decreases: a higher within-population heterozygosity (He) yields a lower F(ST) value. However, the same is true for Q(ST) : a higher mutation rate for the underlying QTL also results in a lower Q(ST) estimate. The effect of mutation rate is equivalent in Q(ST) and F(ST) . Hence, the comparison between Q(ST) and F(ST) remains valid, if one uses neutral markers whose mutation rates are not too high compared to those of quantitative traits. Usage of highly variable neutral markers such as hypervariable microsatellites can lead to serious biases and the incorrect inference that divergent selection has acted on populations. Much of the discussion on F(ST) seems to stem from the misunderstanding that it measures the differentiation of populations, whereas it actually measures the fixation of alleles. In their capacity as measures of population differentiation, Hedrick's G'(ST) and Jost's D reach their maximum value of 1 when populations do not share alleles even when there remains variation within populations, which invalidates them for comparisons with Q(ST) . © 2011 Blackwell Publishing Ltd.

  7. The effect of optical substrates on micro-FTIR analysis of single mammalian cells.

    Science.gov (United States)

    Wehbe, Katia; Filik, Jacob; Frogley, Mark D; Cinque, Gianfelice

    2013-02-01

    The study of individual cells with infrared (IR) microspectroscopy often requires living cells to be cultured directly onto a suitable substrate. The surface effect of the specific substrates on the cell growth-viability and associated biochemistry-as well as on the IR analysis-spectral interference and optical artifacts-is all too often ignored. Using the IR beamline, MIRIAM (Diamond Light Source, UK), we show the importance of the substrate used for IR absorption spectroscopy by analyzing two different cell lines cultured on a range of seven optical substrates in both transmission and reflection modes. First, cell viability measurements are made to determine the preferable substrates for normal cell growth. Successively, synchrotron radiation IR microspectroscopy is performed on the two cell lines to determine any genuine biochemically induced changes or optical effect in the spectra due to the different substrates. Multivariate analysis of spectral data is applied on each cell line to visualize the spectral changes. The results confirm the advantage of transmission measurements over reflection due to the absence of a strong optical standing wave artifact which amplifies the absorbance spectrum in the high wavenumber regions with respect to low wavenumbers in the mid-IR range. The transmission spectra reveal interference from a more subtle but significant optical artifact related to the reflection losses of the different substrate materials. This means that, for comparative studies of cell biochemistry by IR microspectroscopy, it is crucial that all samples are measured on the same substrate type.

  8. Exercício etnográfico em clubes de prostitutas na região central de Florianópolis/SC: desafios de uma experiência interdisciplinar

    Directory of Open Access Journals (Sweden)

    Leandro Cisneros

    2013-03-01

    Full Text Available http://dx.doi.org/10.5007/2178-4582.2012v46n2p499 O presente trabalho é o resultado de um exercício de prática etnográfica proposto na disciplina de Métodos Antropológicos, coordenada por Miriam Grossi, Carmen Rial, Tânia Welter e Mônica Suarez,oferecida para estudantes de doutorado do Programa de Pós-Graduação Interdisciplinar em Ciências Humanas. Propusemo-nos a pesquisar um dos campos fechados da Antropologia, o da prostituição, na região urbana de Florianópolis/SC. Nossa contribuiçãoà reflexão sobre a interdisciplinaridade se faz presente na construção teórico-metodológica do campo de pesquisa, a partir das nossas trajetórias profissionais e percursos de estudo feitos em três áreas, orientações e instituições diferentes.

  9. KEGGtranslator: visualizing and converting the KEGG PATHWAY database to various formats.

    Science.gov (United States)

    Wrzodek, Clemens; Dräger, Andreas; Zell, Andreas

    2011-08-15

    The KEGG PATHWAY database provides a widely used service for metabolic and nonmetabolic pathways. It contains manually drawn pathway maps with information about the genes, reactions and relations contained therein. To store these pathways, KEGG uses KGML, a proprietary XML-format. Parsers and translators are needed to process the pathway maps for usage in other applications and algorithms. We have developed KEGGtranslator, an easy-to-use stand-alone application that can visualize and convert KGML formatted XML-files into multiple output formats. Unlike other translators, KEGGtranslator supports a plethora of output formats, is able to augment the information in translated documents (e.g. MIRIAM annotations) beyond the scope of the KGML document, and amends missing components to fragmentary reactions within the pathway to allow simulations on those. KEGGtranslator is freely available as a Java(™) Web Start application and for download at http://www.cogsys.cs.uni-tuebingen.de/software/KEGGtranslator/. KGML files can be downloaded from within the application. clemens.wrzodek@uni-tuebingen.de Supplementary data are available at Bioinformatics online.

  10. Investigations on the isoprenoid biosynthesis in the green alga Scenedesmus obliquus by using the 13C-labelling technique

    International Nuclear Information System (INIS)

    Schwender, J.

    1995-01-01

    The biosynthesis of several prenyllipids (isoprenoid lipids) of the green alga Scendesmus obliquus was investigated. The aim was to verify, whether the biosynthesis of isopentenyl diphosphate (IPP) in Scenedesmus proceeds according to the classical acetate mevalonate pathway or to an alternative pathway. An alternative pathway for IPP formation has recently been detected in some eubacteria by the group of Prof. M. Rohmer. Some inhibition tests were performed with mevinolin, a specific inhibitor of HMG-CoA reductase which yields mevalonic acid. Mevinolin should block the biosynthesis of such isoprenoids which are formed via the acetate mevalonate pathway. Scenedesmus was grown heterotrophically on 13 C-labelled glucose or acetate. After isolation and purification of 13 C-labelled phytol (side chains of chlorophylls), β-carotene, lutein, plastoquinone-9 and three sterol compounds, the enrichment of 13 C at different carbon-positions of the labelled compounds was determined. This was achieved by the 13 C-NMR technique in cooperation with Miriam Seemann of the group of Prof. M. Rohmer in Mullhouse/France. (orig.) [de

  11. Cine-Club

    CERN Multimedia

    Cine-Club

    2011-01-01

    Thursday 27 October 2011 at 20:30 CERN Council Chamber Private By: Saverio Costanzo (Italy, 2004) 90 min With: Mohammed Bakri, Lior Miller, Hend Ayoub A Palestinian family with five children lives outside town, near Israeli settlements. Samia, the wife, wants to leave; so does one teen son. Mohammad, the patriarch, is adamant that he is staying. Two of his adolescent children want to fight. His is the passive aggression of non-violent witness. Israeli soldiers burst into the home, taking over the second floor. At night, the family is locked in the living room. We see the effects of the occupation on the children and on the marriage. Through the eyes of Miriam, the older daughter, we watch the soldiers from her hiding place. Jamal, the eldest son, sets a trap with a grenade. Characters call upon Allah. Chaos and death are close. Original version arabic / english / hebrew; english subtitles Entrance: 2 CHF Projection from DVD http://cineclub.web.cern.ch/Cineclub/ Thursday 3 November 2011 a...

  12. Non-climacteric ripening and sorbitol homeostasis in plum fruits.

    Science.gov (United States)

    Kim, Ho-Youn; Farcuh, Macarena; Cohen, Yuval; Crisosto, Carlos; Sadka, Avi; Blumwald, Eduardo

    2015-02-01

    During ripening fruits undergo several physiological and biochemical modifications that influence quality-related properties, such as texture, color, aroma and taste. We studied the differences in ethylene and sugar metabolism between two genetically related Japanese plum cultivars with contrasting ripening behaviors. 'Santa Rosa' (SR) behaved as a typical climacteric fruit, while the bud sport mutant 'Sweet Miriam' (SM) displayed a non-climacteric ripening pattern. SM fruit displayed a delayed ripening that lasted 120 days longer than that of the climacteric fruit. At the full-ripe stage, both cultivars reached similar final size and weight but the non-climacteric fruits were firmer than the climacteric fruits. Fully ripe non-climacteric plum fruits, showed an accumulation of sorbitol that was 2.5 times higher than that of climacteric fruits, and the increase in sorbitol were also paralleled to an increase in sucrose catabolism. These changes were highly correlated with decreased activity and expression of NAD(+)-dependent sorbitol dehydrogenase and sorbitol oxidase and increased sorbitol-6-phosphate dehydrogenase activity, suggesting an enhanced sorbitol synthesis in non-climacteric fruits. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  13. β-glycosphingolipids ameliorated non-alcoholic steatohepatitis in the Psammomys obesus model

    Directory of Open Access Journals (Sweden)

    Zigmond E

    2014-10-01

    Full Text Available Ehud Zigmond,1,* Oshrat Tayer-Shifman,1,* Gadi Lalazar,1 Ami Ben Ya'acov,1 Sarah Weksler-Zangen,2 David Shasha,1 Miriam Sklair-Levy,3 Lidya Zolotarov,1 Zvi Shalev,1 Rony Kalman,2 Ehud Ziv,2 Itamar Raz,2 Yaron Ilan1 1Liver Unit, 2Diabetes Unit, 3Department of Radiology, Hebrew University-Hadassah Medical Center, Jerusalem, Israel *These authors contributed equally to this workAbstract: Liver steatosis is a common characteristic of obesity and type 2 diabetes, and fatty liver disease is increasingly recognized as a major health burden. Accumulating evidence suggests that β-glycosphingolipids play an important role in insulin sensitivity and thus could affect hepatic steatosis. To determine the effect associated with β-glycosphingolipid-mediated amelioration of liver injury, seven groups of Psammomys obesus on a high-energy diet were studied. Animals were treated with daily injections of β-glucosylceramide, β-lactosylceramide, or a combination of both. β-glycosphingolipids ameliorated the hepatic injury manifested by decreased liver enzymes, liver weight, and hepatic fat, and improved liver histology. Administration of both β-glucosylceramide and β-lactosylceramide also decreased interferon (IFN-γ serum levels. These effects were associated with improved serum cholesterol and triglyceride levels. These data suggest that β-glycosphingolipids ameliorate liver injury in an animal model of nonalcoholic steatohepatitis.Keywords: NAFLD, glycolipids, STAT, NASH, insulin resistance, diabetes

  14. Fictionalization, conscientization and the trope of exile in Amandla and Third Generation

    Directory of Open Access Journals (Sweden)

    J. Geertsema

    1993-05-01

    Full Text Available The purpose of this article is to examine Amandla (by Miriam TIali and Third Generation (by Sipho Sepamla as anti-apartheid novels of resistance which are faced by a number of serious contradictions. The article is an attempt to analyse the ways in which these texts seek to cope, on the one hand, with what seems to be a lost cause, a struggle without an end, and on the other hand with their own status as fictional texts which attempt to change precisely that which seems to deny all possibilities of subversion. Both texts attempt to make sense of a reality which is perceived to be so horrifyingly real as to be fictional (in the sense of the fictive, unreal, ethereal. On the one hand the power of the apartheid state is seen to be insurmountable, and on the other hand, that stale has to be subverted and destroyed. The resulting dialectic, posited in the texts, of the state of affairs in reality and the state of affairs that is desired, can only be solved by the use of the trope of exile as an imaginary resolution to a very real contradiction in order to achieve at least some measure of conscientization in the readership.

  15. La investigación sobre fisiognomía y expresión de las pasiones: objetivos y metodología

    Directory of Open Access Journals (Sweden)

    Albero Muñoz, María del Mar

    2008-12-01

    Full Text Available The search of the emotional expressivity in the arts during the 17th century, guided both artists and theorist to the analysis of the expression of the passions, the physiognomy and the appearance of emotions. This subject had been developed into the artistic literature from the ancient times until this century by writers like PseudoAristotle, Alberti, Leonardo or Gaurico. This study analyzes the research methods applied to know the influence of these theories into the Spanish XVII century artistic literature. Mainly in the study of the treatises wrote by Vicente Carducho, Francisco Pacheco and Jusepe Martinez, showing the different paths used by them in order to guide other painters to illustrate the emotions of the soul.

  16. Vegetation pattern formation in semiarid systems induced by long-range competition in the absence of facilitation mechanisms.

    Science.gov (United States)

    Martinez-Garcia, Ricardo; Calabrese, Justin M.; Hernandez-Garcia, Emilio; Lopez, Cristobal

    2014-05-01

    Regular patterns and spatial organization of vegetation have been observed in many arid and semiarid ecosystems worldwide, covering a diverse range of plant taxa and soil types. A key common ingredient in these systems is that plant growth is severely limited by water availability, and thus plants likely compete strongly for water. The study of such patterns is especially interesting because their features may reveal much about the underlying physical and biological processes that generated them in addition to giving information on the characteristics of the ecosystem. It is possible, for instance, to infer their resilience against anthropogenic disturbances or climatic changes that could cause abrupt shifts in the system and lead it to a desert state. Therefore much research has focused on identifying the underlying mechanisms that can produce spatial patterning in water-limited systems (Klausmeier, 1999). They are believed to arise from the interplay between long-range competition and facilitation processes acting at smaller distances (Borgogno et al., 2009). This combination of mechanisms is justified by arguing that water percolates more readily through the soil in vegetated areas (short range), and that plants compete for water resources over greater distances via long lateral roots (long range). However, recent studies have shown that even in the limit of local facilitation patterns may still appear (Martinez-Garcia et al., 2013). In this work (Martinez-Garcia et al., 2013b), we show that, under rather general conditions, long-range competition alone is the minimal ingredient to shape gapped and stripped vegetation patterns typical of models that also account for facilitation in addition to competition. To this end we propose a simple, general model for the dynamics of vegetation, which includes only long-range competition between plants. Competition is introduced through a nonlocal term, where the kernel function quantifies the intensity of the interaction

  17. Ancient loons stories Pingree told me

    CERN Document Server

    Davis, Philip J

    2016-01-01

    The book is a collection of short stories, small anecdotes in the life of some historical characters. More concretely, it focuses on the oddities and singularities of some well-known historical figures, not only in science, but also in arts, politics and social sciences. … the book shows the fascination for ancient history, the treasures hidden in original sources and the importance of exploring unusual connections.-Javier Martinez, The European Mathematical Society, January 2013… a rambling, illuminating and thoroughly enjoyable bio/autobiographical and historical sketch, setting Pingree's immense erudition in its professional and intellectual context. Besides a string of amusing and intriguing anecdotes plentifully sprinkled with photos and sketches, this small volume supplies a valuable reminder of how complex, surprising and just plain strange the history of the exact sciences can be.-Kim Plofker, MAA Reviews, October 2012.

  18. Bridge-builders in the peripheral region

    DEFF Research Database (Denmark)

    Leick, Birgit; Gretzinger, Susanne

    (Sotarauta and Pulkkinen 2011). In a similar vein, Burt (2005) argues that actors can drive networking and innovation through connecting a priori unconnected firms and thereby integrate diverse resources and knowledge for the sake of benefitting and developing a business network. Belso-Martinez et al. (2015...... development and, indirectly, local development in the periphery through enhancing networking and innovativeness. As a stylized fact, peripheral regions face important limitations to innovation-based economic development (Danson and De Souza 2012), which impair the potential for firm growth, notably of small......Maggio [1988] versus the concept of network brokers developed by Burt [2005]) into a comparative conceptual framework on innovation-based business networks in peripheral regions. We argue that agents who work for changing the firms’ behaviour towards a more collaborative stance and greater openness...

  19. Slug flow model for infiltration into fractured porous media

    International Nuclear Information System (INIS)

    Martinez, M.J.

    1999-01-01

    A model for transient infiltration into a periodically fractured porous layer is presented. The fracture is treated as a permeable-walled slot and the moisture distribution is in the form of a slug being an advancing meniscus. The wicking of moisture from the fracture to the unsaturated porous matrix is a nonlinear diffusion process and is approximately by self-similar solutions. The resulting model is a nonlinear Volterra integral equation with a weakly singular kernel. Numerical analysis provides solutions over a wide range of the parameter space and reveals the asymptotic forms of the penetration of this slug in terms of dimensionless variables arising in the model. The numerical solutions corroborate asymptotic results given earlier by Nitao and Buscheck (1991), and by Martinez (1988). Some implications for the transport of liquid in fractured rock are discussed

  20. Determination of source terms in a degenerate parabolic equation

    International Nuclear Information System (INIS)

    Cannarsa, P; Tort, J; Yamamoto, M

    2010-01-01

    In this paper, we prove Lipschitz stability results for inverse source problems relative to parabolic equations. We use the method introduced by Imanuvilov and Yamamoto in 1998 based on Carleman estimates. What is new here is that we study a class of one-dimensional degenerate parabolic equations. In our model, the diffusion coefficient vanishes at one extreme point of the domain. Instead of the classical Carleman estimates obtained by Fursikov and Imanuvilov for non degenerate equations, we use and extend some recent Carleman estimates for degenerate equations obtained by Cannarsa, Martinez and Vancostenoble. Finally, we obtain Lipschitz stability results in inverse source problems for our class of degenerate parabolic equations both in the case of a boundary observation and in the case of a locally distributed observation

  1. Neuromorphic olfaction neuromorphic olfaction

    CERN Document Server

    Persaud, Krishna C; Marco, Santiago

    2016-01-01

    Engineering Aspects of Olfaction; Krishna C. PersaudStudy of the Coding Efficiency of Populations of OlfactoryReceptor Neurons and Olfactory Glomeruli; Agustín Gutiérrez-Gálvez and Santiago MarcoMimicking Biological Olfaction with Very Large ChemicalArrays; Mara Bernabei, Romeo Beccherelli, Emiliano Zampetti,Simone Pantalei, and Krishna C. PersaudThe Synthetic Moth: A Neuromorphic Approach towardArtificial Olfaction in Robots; Vasiliki Vouloutsi, Lucas L. Lopez-Serrano,Zenon Mathews, Alex Escuredo Chimeno, Andrey Ziyatdinov, Alexandre Perera i Lluna, Sergi Bermúdez i Badia, and Paul F. M. J. Verschure Reactive and Cognitive Search Strategies for Olfactory Robots; Dominique Martinez and Eduardo Martin MoraudPerformance of a Computational Model of the MammalianOlfactory System; Simon Benjaminsson, Pawel Herman, and Anders LansnerIndex.

  2. Eelgrass habitat near Liberty Bay: Chapter 5

    Science.gov (United States)

    Dinicola, Richard S.; Takesue, Renee K.

    2015-01-01

    Seagrasses are a widespread type of marine flowering plants that grow in nearshore intertidal and subtidal zones. Seagrass beds are ecologically important because they affect physical, biological, and chemical characteristics of nearshore habitat, and they are sensitive to changes in coastal water quality (Stevenson and others, 1993; Koch, 2001; Martinez-Crego and others, 2008). Zostera marina, commonly known as eelgrass, is protected by a no-net-loss policy in Washington State where it may be used as spawning habitat by herring, a key prey species for salmon, seabirds, and marine mammals (Bargmann, 1998). Eelgrass forms broad meadows in shallow embayments or narrow fringes on open shorelines (Berry and others, 2003). Anthropogenic activities that increase turbidity, nutrient loading, and physical disturbance at the coast can result in dramatic seagrass decline (Ralph and others, 2006).

  3. Use of geochemical biomarkers in bottom sediment to track oil from a spill, San Francisco Bay, California

    Science.gov (United States)

    Hostettler, F.D.; Rapp, J.B.; Kvenvolden, K.A.

    1992-01-01

    In April 1988, approximately 1500 m3 of a San Joaquin Valley crude oil were accidentally released from a Shell Oil Co. refinery near Martinez, Californa. The oil flowed into Carquinez Strait and Suisun Bay in northern San Francisco Bay Sediment and oil samples were collected within a week and analysed for geochemical marker compounds in order to track the molecular signature of the oil spill in the bottom sediment. Identification of the spilled oil in the sediment was complicated by the degraded nature of the oil and the similarity of the remaining, chromatographically resolvable constituents to those already present in the sediments from anthropogenic petroleum contamination, pyrogenic sources, and urban drainage. Ratios of hopane and sterane biomarkers, and of polycyclic aromatic hydrocarbons and their alkylated derivatives best identified the oil impingement. They showed the oil impact at this early stage to be surficial only, and to be patchy even within an area of heavy oil exposure.

  4. New awards for CERN science

    CERN Multimedia

    2013-01-01

    Earlier this week, the European Physical Society (EPS) announced its High Energy and Particle Physics prizes for 2013, and I’m pleased to say that the LHC featured highly. With all that has been happening in the last few years, that’s perhaps not too surprising, but these awards nevertheless constitute a great honour for our community.   The High Energy and Particle Physics Prize went to the ATLAS and CMS collaborations “for the discovery of a Higgs boson, as predicted by the Brout-Englert-Higgs mechanism”, and to Michel Della Negra, Peter Jenni and Tejinder Virdee “for their pioneering and outstanding leadership roles in the making of the ATLAS and CMS experiments”. Among the other awards, the Young Experimental Physicist Prize went to Diego Martinez Santos “for his outstanding contributions to the trigger and commissioning of the LHCb experiment, and the analyses leading to first evidence for the rare decay B0s→ ...

  5. Measuring cultural awareness of nursing students: a first step toward cultural competency.

    Science.gov (United States)

    Krainovich-Miller, Barbara; Yost, Jennifer M; Norman, Robert G; Auerhahn, Carolyn; Dobal, May; Rosedale, Mary; Lowry, Melissa; Moffa, Christine

    2008-07-01

    This pilot study was designed to measure nursing students' level of cultural awareness. It replicated phase II of Rew, Becker, Cookston, Khosropour, & Martinez's (2003) methodological study that developed and tested a Cultural Awareness Scale (CAS). Using a cross-sectional design, the CAS was distributed to nursing students in three nursing programs' (bachelor's, master's, doctoral) beginning and end courses. Cronbach's alpha for the CAS Total instrument was 0.869, with subscale scores ranging from 0.687 to 0.902, comparable to the findings of Rew et al. Given the limitations of this study, results must be viewed with a degree of caution. Recommendations include further educational research in the form of psychometric testing of the CAS among nursing students, including refinement of both the CAS instrument and the demographic tool. The authors also recommend that studies be conducted to determine the validity and reliability of the CAS with nurses in the health care arena.

  6. Phase transition for black holes with scalar hair and topological black holes

    International Nuclear Information System (INIS)

    Myung, Yun Soo

    2008-01-01

    We study phase transitions between black holes with scalar hair and topological black holes in asymptotically anti-de Sitter spacetimes. As the ground state solutions, we introduce the non-rotating BTZ black hole in three dimensions and topological black hole with hyperbolic horizon in four dimensions. For the temperature matching only, we show that the phase transition between black hole with scalar hair (Martinez-Troncoso-Zanelli black hole) and topological black hole is second-order by using differences between two free energies. However, we do not identify what order of the phase transition between scalar and non-rotating BTZ black holes occurs in three dimensions, although there exists a possible decay of scalar black hole to non-rotating BTZ black hole

  7. Extensive cardinal parameter model to predict growth of pseudomonads in salt-reduced lightly preserved seafood

    DEFF Research Database (Denmark)

    Martinez Rios, Veronica; Dalgaard, Paw

    Interest in and demand for preserved seafood with reduced salt/sodium content is increasing. As a consequence of the reduced salt content potential growth of psychrotolerant pseudomonads to unacceptable high concentration where they cause product spoilage is an increasing challenge. Innovation...... include the effect of temperatures and salt. However, these simple secondary models do not include the effect of a broader range of product characteristics and therefore they cannot be used to predict how the inhibiting effect of salt can be replaced by changes in other environmental factors The objective...... and including terms for temperature, pH, aw/NaCl, lactic- and sorbic acids (Martinez-Rios et al., Int. J. Food Microbiol. 216. 110-120, 2016). MIC-values for acetic-, benzoic- and citric acids were determined in broth and terms modelling their antimicrobial effect were added to the model. The new and expanded...

  8. Mathematics training for the teaching of basic knowledge in times of teaching school reform of Parana (Year 1920

    Directory of Open Access Journals (Sweden)

    Iara da Silva França

    2016-06-01

    Full Text Available Abstract The article discusses the mathematical training of primary teachers in Paraná and aims to understand how elementary mathematical knowledge was included in the reform carried out by Lysimaco Ferreira da Costa, in the 1920’s and directed by Prieto Martinez for the modernization of the state’s primary education. Supported by theoretical and methodological framework of cultural history, this study is guided by the question: Considering the Reform of teaching school and thinking about the mathematics education of Paraná teachers, what has changed, why has it changed and what for? With the reform subjects more focused on practical teaching in primary school were introduced, and that favored the renewal of teaching methods and teaching resources, curriculum reorganization which reflected in the quality of Math education of future teachers in the state’s primary education. Keywords: Mathematics Teaching. Primary Education Teacher. History of Education.

  9. Don Quixote an Celia: the desire to live other lives

    Directory of Open Access Journals (Sweden)

    María Jesús Fraga Fernández-Cuevas

    2012-12-01

    Full Text Available The present study explores the parallelisms between Don Quixote and Elena Fortun’s novels Celia. First, it enumerates the various activities that prove the author’s interest in Cervantes and his work, as well as the possible intervention of her mentor, Maria Martinez Sierra, in the genesis of the child’s character. Both novels, of dialogical nature, share an episodic structure articulated by a weak storyline. Its protagonists are animated by the desire to live the lives of the characters of their favorite readings. They confuse fantasy and reality causing situations whose results are almost always adverse. If Don Quixote dies back to the reason, so will Celia, the girl, with her entry into adulthood by resigning her fantasies, which will be taken up by new generations of children.

  10. Microbial heterotrophic metabolic rates constrain the microbial carbon pump

    Digital Repository Service at National Institute of Oceanography (India)

    Robinson, C.; Ramaiah, N.

    (2008). 10. P.A. del Giorgio, J. J. Cole, in MicrobialEcologyoftheOceans D. L. Kirchman Ed. (JohnWiley & Sons, Inc. NewYork ed. 1. 2000),pp. 289–325. 11. A. B. Burd etal., DeepSeaRes.II 57, 1557 (2010). 12. S. Martinez-García, E. Fernández, M.... R.A. Straza, D. L. Kirchman, Aquat.Microb.Ecol. 62, 267(2011). 16. O. Hoegh-Guldberg, J. F. Bruno, Science 328,1523 (2010). 17. J. Piontek, M. Lunau, N. Handel, C. Borchard, M.Wurst,A. Engel, Biogeosciences 7, 1615 (2010). 18. J. K.Apple, P.A. del...

  11. Political Ecology of Globality and Difference

    International Nuclear Information System (INIS)

    Escobar, Arturo

    2008-01-01

    This article is about politics of difference and sameness that accompany the enactment of globality. Is is about the dynamic of the imperial globality and its global regime of coloniality as one of the most salient features of the modern colonial world system in the early twenty first century. It is also, in a literal sense, about the geopolitics of knowledge. It develops its argument, in part, borrowing from Joan Martinez Alier's definition of political ecology as the study of ecological distribution conflicts. It argues that a Eurocentric globality has an obligatory counterpart in the systematic act of encubrimiento del otro. Kinds of global coloniality Six concepts are key to understand this argument: place, capital, nature, development e identity, Colombia is a theater of this imperial globality

  12. NSO News - February 2014

    Energy Technology Data Exchange (ETDEWEB)

    Beck, James B. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-03-04

    Welcome to the February newsletter. Recent highlights include progress on the nuclear deal with Iran, the continued challenges with North Korea, the developing situation in Ukraine and Georgia, and issues related to the Unites States Nuclear Deterrent. In this newsletter, some key messages from the recent Nuclear Deterrent summit, which is annually held in Washington, DC, asre also included. The NSO recently hosted a workshop organized with the Center for International Security and Cooperation (CISAC) at Stanford University on how other States view nuclear weapons and deterrence. Participants included Dr. Bradley Roberts, Gen. (Ret.) Robert Kehler, Bridge Colby, Dr. Robert Gromoll, and other experts. If you would like to have a more in-depth discussion on this or any related topics, please contact Sylvia Martinez at 667-6120 to set up some time.

  13. State-dependent fluorescence of neutral atoms in optical potentials

    Science.gov (United States)

    Martinez-Dorantes, M.; Alt, W.; Gallego, J.; Ghosh, S.; Ratschbacher, L.; Meschede, D.

    2018-02-01

    Recently we have demonstrated scalable, nondestructive, and high-fidelity detection of the internal state of 87Rb neutral atoms in optical dipole traps using state-dependent fluorescence imaging [M. Martinez-Dorantes, W. Alt, J. Gallego, S. Ghosh, L. Ratschbacher, Y. Völzke, and D. Meschede, Phys. Rev. Lett. 119, 180503 (2017), 10.1103/PhysRevLett.119.180503]. In this paper we provide experimental procedures and interpretations to overcome the detrimental effects of heating-induced trap losses and state leakage. We present models for the dynamics of optically trapped atoms during state-dependent fluorescence imaging and verify our results by comparing Monte Carlo simulations with experimental data. Our systematic study of dipole force fluctuations heating in optical traps during near-resonant illumination shows that off-resonant light is preferable for state detection in tightly confining optical potentials.

  14. Development and validation of extensive growth and growth boundary models for psychrotolerant pseudomonads in seafood, meat and vegetable products

    DEFF Research Database (Denmark)

    Martinez Rios, Veronica; Dalgaard, Paw

    Extensive growth and growth boundary models were developed and validated for psychrotolerant pseudomonads growing in seafood, meat and vegetable products. The new models were developed by expanding anexisting cardinal parameter-type model for growth of pseudomonads in milk (Martinez-Rios et al......, when observed and predicted μmax -values were compared. Thus, on average μmax -values for seafood and meat products were overestimated by 14%. Additionally, the reference growth rate parameter μref25˚C was calibrated by fitting the model to 21 μmax -values in vegetable products. This resulted in a μref......25˚C -value of 0.54 1/h. The calibrated vegetable model wassuccessfully validated using 51 μmax -values for psychrotolerant pseudomonads in vegetables. Average bias and accuracy factor values of 1.24 and 1.38 were obtained, respectively. Lag time models were developed by using relative lag times from...

  15. Estimate of the emissions of methane in a dairy farm and a proposal of mitigation

    International Nuclear Information System (INIS)

    Schmidt, R; Alvarez, E; Gely, M; Pagano, A; Crozza, D

    2005-01-01

    The methane represents one of the most potent greenhouse gas and recent inventories express that the systems of handling of the manure of the livestock have influence in the global emissions of methane (Martinez et. al, 2003).This residue, during the periods of storage to open sky, suffers a natural anaerobic decomposition and gases like ammonium, hydrogen, sulfhydric, methane and dioxide of carbon; are generated and emitted to the atmosphere (EPA, 1999, Misselbrook et. al, 2001; Martinez et. al, 2003).In a report presented by the EPA (EPA, 1999) it was estimated that the methane emission originated in United States (1997) for the handling of the manure of the livestock ascended to 3.0 T g., what represents 10% of the total content of the methane emissions in that country.It is also expected that these emissions caused by the cattle residual grow above 25% from the 2000 to the 2020.In Argentina, and in particular in the region that includes the territorial space of the present study, in the Party of Olavarria located in the center of the Buenos Aires Province, it is considered that there are 8265 heads of bovine livestock, distributed under different forms of exploitation, dairy farms, cattle-breeding ranch and feedlots.These figures show the clearly incipient advance of the bovine livestock in this area, showing that the values of generated methane can influence thoroughly in the contribution of the greenhouse gas.The objective of the present study resides in carrying out an estimate of the equivalent quantity of CO 2 that is emitted to the atmosphere and how much it could decrease if the methodology of anaerobic digestion is applied, for the conversion of the bovine manure in biogas

  16. Pharmaceutical care in smoking cessation

    Directory of Open Access Journals (Sweden)

    Marín Armero A

    2015-01-01

    Full Text Available Alicia Marín Armero,1 Miguel A Calleja Hernandez,2 Sabina Perez-Vicente,3 Fernando Martinez-Martinez4 1Community Pharmacy, Murcia, Spain; 2Hospital Pharmacy, University Hospital Virgen de las Nieves, Granada, Spain; 3Result Evaluation Unit, Institute of Biomedicine, Sevilla, Spain; 4Research Unit in Pharmaceutical Care, University of Granada, Granada, Spain Abstract: As a determining factor in various diseases and the leading known cause of preventable mortality and morbidity, tobacco use is the number one public health problem in developed countries. Facing this health problem requires authorities and health professionals to promote, via specific programs, health campaigns that improve patients’ access to smoking cessation services. Pharmaceutical care has a number of specific characteristics that enable the pharmacist, as a health professional, to play an active role in dealing with smoking and deliver positive smoking cessation interventions. The objectives of the study were to assess the efficacy of a smoking cessation campaign carried out at a pharmaceutical care center and to evaluate the effects of pharmaceutical care on patients who decide to try to stop smoking. The methodology was an open, analytical, pre–post intervention, quasi-experimental clinical study performed with one patient cohort. The results of the study were that the promotional campaign for the smoking cessation program increased the number of patients from one to 22, and after 12 months into the study, 43.48% of the total number of patients achieved total smoking cessation. We can conclude that advertising of a smoking cessation program in a pharmacy increases the number of patients who use the pharmacy’s smoking cessation services, and pharmaceutical care is an effective means of achieving smoking cessation. Keywords: community pharmacy, health campaign, tobacco cessation, nicotine replacement therapy

  17. Generic and scientific constraints involving geoethics and geoeducation in planetary geosciences

    Science.gov (United States)

    Martínez-Frías, Jesús

    2013-04-01

    Geoscience education is a key factor in the academic, scientific and professional progress of any modern society. Geoethics is an interdisciplinary field, which involves Earth and Planetary Sciences as well as applied ethics, regarding the study of the abiotic world. These coss-cutting interactions linking scientific, societal and cultural aspects, consider our planet, in its modern approach, as a system and as a model. This new perspective is extremely important in the context of geoducation in planetary geosciences. In addition, Earth, our home planet, is the only planet in our solar system known to harbor life. This also makes it crucial to develop any scientific strategy and methodological technique (e.g. Raman spectroscopy) of searching for extraterrestrial life. In this context, it has been recently proposed [1-3] that the incorporation of the geoethical and geodiversity issues in planetary geology and astrobiology studies would enrich their methodological and conceptual character (mainly but not only in relation to planetary protection). Modern geoscience education must take into account that, in order to understand the origin and evolution of our planet, we need to be aware that the Earth is open to space, and that the study of meteorites, asteroids, the Moon and Mars is also essential for this purpose (Earth analogs are also unique sites to define planetary guidelines). Generic and scientific constraints involving geoethics and geoeducation should be incorporated into the teaching of all fundamental knowledge and skills for students and teachers. References: [1] Martinez-Frias, J. et al. (2009) 9th European Workshop on Astrobiology, EANA 09, 12-14 October 2009, Brussels, Belgiam. [2] Martinez-Frias, J., et al. (2010) 38th COSPAR Scientific Assembly. Protecting the Lunar and Martian Environments for Scientific Research, Bremen, Germany, 18-25 July. [3] Walsh et al. (2012) 43rd Lunar and Planetary Science Conference, 1910.pdf

  18. Present, future, and novel bioclimates of the San Francisco, California region

    Science.gov (United States)

    Torregrosa, Alicia; Taylor, Maxwell D.; Flint, Lorraine E.; Flint, Alan L.

    2013-01-01

    Bioclimates are syntheses of climatic variables into biologically relevant categories that facilitate comparative studies of biotic responses to climate conditions. Isobioclimates, unique combinations of bioclimatic indices (continentality, ombrotype, and thermotype), were constructed for northern California coastal ranges based on the Rivas-Martinez worldwide bioclimatic classification system for the end of the 20th century climatology (1971–2000) and end of the 21st century climatology (2070–2099) using two models, Geophysical Fluid Dynamics Laboratory (GFDL) model and the Parallel Climate Model (PCM), under the medium-high A2 emission scenario. The digitally mapped results were used to 1) assess the relative redistribution of isobioclimates and their magnitude of change, 2) quantify the loss of isobioclimates into the future, 3) identify and locate novel isobioclimates projected to appear, and 4) explore compositional change in vegetation types among analog isobioclimate patches. This study used downscaled climate variables to map the isobioclimates at a fine spatial resolution −270 m grid cells. Common to both models of future climate was a large change in thermotype. Changes in ombrotype differed among the two models. The end of 20th century climatology has 83 isobioclimates covering the 63,000 km2 study area. In both future projections 51 of those isobioclimates disappear over 40,000 km2. The ordination of vegetation-bioclimate relationships shows very strong correlation of Rivas-Martinez indices with vegetation distribution and composition. Comparisons of vegetation composition among analog patches suggest that vegetation change will be a local rearrangement of species already in place rather than one requiring long distance dispersal. The digitally mapped results facilitate comparison with other Mediterranean regions. Major remaining challenges include predicting vegetation composition of novel isobioclimates and developing metrics to compare

  19. Present, future, and novel bioclimates of the San Francisco, California region.

    Directory of Open Access Journals (Sweden)

    Alicia Torregrosa

    Full Text Available Bioclimates are syntheses of climatic variables into biologically relevant categories that facilitate comparative studies of biotic responses to climate conditions. Isobioclimates, unique combinations of bioclimatic indices (continentality, ombrotype, and thermotype, were constructed for northern California coastal ranges based on the Rivas-Martinez worldwide bioclimatic classification system for the end of the 20(th century climatology (1971-2000 and end of the 21(st century climatology (2070-2099 using two models, Geophysical Fluid Dynamics Laboratory (GFDL model and the Parallel Climate Model (PCM, under the medium-high A2 emission scenario. The digitally mapped results were used to 1 assess the relative redistribution of isobioclimates and their magnitude of change, 2 quantify the loss of isobioclimates into the future, 3 identify and locate novel isobioclimates projected to appear, and 4 explore compositional change in vegetation types among analog isobioclimate patches. This study used downscaled climate variables to map the isobioclimates at a fine spatial resolution -270 m grid cells. Common to both models of future climate was a large change in thermotype. Changes in ombrotype differed among the two models. The end of 20(th century climatology has 83 isobioclimates covering the 63,000 km(2 study area. In both future projections 51 of those isobioclimates disappear over 40,000 km(2. The ordination of vegetation-bioclimate relationships shows very strong correlation of Rivas-Martinez indices with vegetation distribution and composition. Comparisons of vegetation composition among analog patches suggest that vegetation change will be a local rearrangement of species already in place rather than one requiring long distance dispersal. The digitally mapped results facilitate comparison with other Mediterranean regions. Major remaining challenges include predicting vegetation composition of novel isobioclimates and developing metrics to

  20. Assessment of beverage intake and hydration status.

    Science.gov (United States)

    Nissensohn, Mariela; López-Ufano, Marisa; Castro-Quezada, Itandehui; Serra-Majem, Lluis

    2015-02-26

    Water is the main constituent of the human body. It is involved in practically all its functions. It is particularly important for thermoregulation and in the physical and cognitive performance. Water balance reflects water intake and loss. Intake of water is done mainly through consumption of drinking water and beverages (70 to 80%) plus water containing foods (20 to 30%). Water loss is mainly due to excretion of water in urine, faeces and sweat. The interest in the type and quantity of beverage consumption is not new, and numerous approaches have been used to assess beverage intake, but the validity of these approaches has not been well established. There is no standardized questionnaire developed as a research tool for the evaluation of water intake in the general population. Sometimes, the information comes from different sources or from different methodological characteristics which raises problems of the comparability. In the European Union, current epidemiological studies that focus exclusively on beverage intake are scarce. Biomarkers of intake are able to objectively assess dietary intake/status without the bias of self-reported dietary intake errors and also overcome the problem of intra-individual diet variability. Furthermore, some methods of measuring dietary intake used biomarkers to validate the data it collects. Biological markers may offer advantages and be able to improve the estimates of dietary intake assessment, which impact into the statistical power of the study. There is a surprising paucity of studies that systematically examine the correlation of beverages intake and hydration biomarker in different populations. A pilot investigation was developed to evaluate the comparative validity and reliability of newly developed interactive multimedia (IMM) versions compared to validated paper-administered (PP) versions of the Hedrick et al. beverage questionnaire. The study showed that the IMM appears to be a valid and reliable measure to assess

  1. Ranked retrieval of Computational Biology models.

    Science.gov (United States)

    Henkel, Ron; Endler, Lukas; Peters, Andre; Le Novère, Nicolas; Waltemath, Dagmar

    2010-08-11

    The study of biological systems demands computational support. If targeting a biological problem, the reuse of existing computational models can save time and effort. Deciding for potentially suitable models, however, becomes more challenging with the increasing number of computational models available, and even more when considering the models' growing complexity. Firstly, among a set of potential model candidates it is difficult to decide for the model that best suits ones needs. Secondly, it is hard to grasp the nature of an unknown model listed in a search result set, and to judge how well it fits for the particular problem one has in mind. Here we present an improved search approach for computational models of biological processes. It is based on existing retrieval and ranking methods from Information Retrieval. The approach incorporates annotations suggested by MIRIAM, and additional meta-information. It is now part of the search engine of BioModels Database, a standard repository for computational models. The introduced concept and implementation are, to our knowledge, the first application of Information Retrieval techniques on model search in Computational Systems Biology. Using the example of BioModels Database, it was shown that the approach is feasible and extends the current possibilities to search for relevant models. The advantages of our system over existing solutions are that we incorporate a rich set of meta-information, and that we provide the user with a relevance ranking of the models found for a query. Better search capabilities in model databases are expected to have a positive effect on the reuse of existing models.

  2. Genomic Sequencing of Japanese Plum (Prunus salicina Lindl.) Mutants Provides a New Model for Rosaceae Fruit Ripening Studies.

    Science.gov (United States)

    Fernandez I Marti, Angel; Saski, Christopher A; Manganaris, George A; Gasic, Ksenija; Crisosto, Carlos H

    2018-01-01

    It has recently been described that the Japanese plum "Santa Rosa" bud sport series contains variations in ripening pattern: climacteric, suppressed-climacteric and non-climacteric types. This provides an interesting model to study the role of ethylene and other key mechanisms governing fruit ripening, softening and senescence. The aim of the current study was to investigate such differences at the genomic level, using this series of plum bud sports, with special reference to genes involved in ethylene biosynthesis, signal transduction, and sugar metabolism. Genomic DNA, isolated from leaf samples of six Japanese plum cultivars ("Santa Rosa", "July Santa Rosa", "Late Santa Rosa", "Sweet Miriam", "Roysum", and "Casselman"), was used to construct paired-end standard Illumina libraries. Sequences were aligned to the Prunus persica genome, and genomic variations (SNPs, INDELS, and CNV's) were investigated. Results determined 12 potential candidate genes with significant copy number variation (CNV), being associated with ethylene perception and signal transduction components. Additionally, the Maximum Likelihood (ML) phylogenetic tree showed two sorbitol dehydrogenase genes grouping into a distinct clade, indicating that this natural group is well-defined and presents high sequence identity among its members. In contrast, the ethylene group, which includes ACO1, ACS1, ACS4, ACS5, CTR1, ERF1, ERF3, and ethylene-receptor genes, was widely distributed and clustered into 10 different groups. Thus, ACS, ERF, and sorbitol dehydrogenase proteins potentially share a common ancestor for different plant genomes, while the expansion rate may be related to ancestral expansion rather than species-specific events. Based on the distribution of the clades, we suggest that gene function diversification for the ripening pathway occurred prior to family extension. We herein report all the frameshift mutations in genes involved in sugar transport and ethylene biosynthesis detected as well

  3. Long-term safety and efficacy of biosimilar infliximab among patients with inflammatory arthritis switched from reference product

    Directory of Open Access Journals (Sweden)

    Abdalla A

    2017-03-01

    Full Text Available Abuelmagd Abdalla, Niamh Byrne, Richard Conway, Thomas Walsh, Geraldine Mannion, Michael Hanly, Miriam O’Sullivan, Ann Maria Curran, John J Carey Department of Rheumatology, Galway University Hospitals, Galway, Ireland Purpose: To evaluate the efficacy and safety of the biosimilar infliximab in adult patients with inflammatory arthritis switched from reference product in our center. Patients and methods: In April 2014, patients attending our rheumatology service for infliximab infusions were switched from reference product to the biosimilar infliximab following consent and hospital approval. Results: Around 34 patients with inflammatory arthritis were switched from reference product to biosimilar infliximab in 2014: 50% female, mean age 55 years (standard deviation=12.9, mean disease duration 14.79 years (9.7, median duration on infliximab 57 months, and two-thirds on oral disease-modifying antirheumatic drugs. There was no difference in efficacy or safety in the first 6 months of therapy. By the end of 2015, the mean follow-up on biosimilar infliximab was 15.8 (standard deviation=6.3 months. Our results showed no significant difference in Health Assessment Questionnaire score, patient global assessment of disease activity, number of disease flares, or the medication dose between the originator and the biosimilar infliximab. However, reported pain and C-reactive protein values were significantly higher during the longer follow-up period (p=0.043, 0.001 respectively. There was no significant difference in the number of adverse events or infusion reactions during follow-up periods. Only five (14.7% patients discontinued the biosimilar infliximab. Conclusion: Our patients experienced similar efficacy and safety for managing their arthritis with the biosimilar infliximab as the reference product infliximab, but at a much lower cost. Keywords: biologic therapy, rheumatic diseases, biosimilar exchange, infliximab, adult

  4. Multiple sclerosis: patients’ information sources and needs on disease symptoms and management

    Directory of Open Access Journals (Sweden)

    Albert I Matti

    2010-06-01

    Full Text Available Albert I Matti1, Helen McCarl2, Pamela Klaer2, Miriam C Keane1, Celia S Chen11Department of Ophthalmology, Flinders Medical Centre and Flinders University, Bedford Park, SA, Australia; 2The Multiple Sclerosis Society of South Australia and Northern Territory, Klemzig, SA, AustraliaObjective: To investigate the current information sources of patients with multiple sclerosis (MS in the early stages of their disease and to identify patients’ preferred source of information. The relative amounts of information from the different sources were also compared.Methods: Participants at a newly diagnosed information session organized by the Multiple Sclerosis Society of South Australia were invited to complete a questionnaire. Participants were asked to rate on a visual analog scale how much information they had received about MS and optic neuritis from different information sources and how much information they would like to receive from each of the sources.Results: A close to ideal amount of information is being provided by the MS society and MS specialist nurses. There is a clear deficit between what information patients are currently receiving and the amount of information they actually want from various sources. Patients wish to receive significantly more information from treating general practitioners, eye specialists, neurologists, and education sessions. Patients have identified less than adequate information received on optic neuritis from all sources.Conclusion: This study noted a clear information deficit regarding MS from all sources. This information deficit is more pronounced in relation to optic neuritis and needs to be addressed in the future.Practice implications: More patient information and counselling needs to be provided to MS patients even at early stages of their disease, especially in relation to management of disease relapse.Keywords: information sources, information needs, MS patients, optic neuritis

  5. Feasibility and Acceptability of a Web-Based Treatment with Telephone Support for Postpartum Women With Anxiety: Randomized Controlled Trial.

    Science.gov (United States)

    Ashford, Miriam T; Olander, Ellinor K; Rowe, Heather; Fisher, Jane Rw; Ayers, Susan

    2018-04-20

    Postpartum anxiety can have adverse effects on the mother and child if left untreated. Time constraints and stigma are common barriers to postpartum treatment. Web-based treatments offer potential flexibility and anonymity. What Am I Worried About (WaWa) is a self-guided treatment based on cognitive-behavioral and mindfulness principles for women experiencing postpartum anxiety. WaWa was developed in Australia and consists of 9 modules with optional weekly telephone support. WaWa was adapted to a Web-based version for use in England (Internet-based What Am I Worried About, iWaWa). This study aimed to investigate the feasibility (engagement and usability) and acceptability (usefulness, satisfaction, and helpfulness) of iWaWa among English postpartum women with anxiety. Postpartum (parenting styles. Despite interest in iWaWa, the results suggest that both the study and iWaWa were not feasible in the current format. However, this first trial provides useful evidence about treatment format and content preferences that can inform iWaWa's future development, as well as research and development of Web-based postpartum anxiety treatments, in general, to optimize adherence. ClinicalTrials.gov NCT02434406; https://clinicaltrials.gov/ct2/show/NCT02434406 (Archived by WebCite at http://www.webcitation.org/6xTq7Bwmd). ©Miriam T Ashford, Ellinor K Olander, Heather Rowe, Jane RW Fisher, Susan Ayers. Originally published in JMIR Mental Health (http://mental.jmir.org), 20.04.2018.

  6. Contraception and family planning among HIV-seroconcordant and -serodiscordant couples in the US and Zambia

    Directory of Open Access Journals (Sweden)

    Deborah L Jones

    2010-05-01

    Full Text Available Deborah L Jones1, Olga Villar-Loubet1, Chipepo Kankasa2, Ndashi Chitalu2, Miriam Mumbi2, Stephen M Weiss11Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, USA; 2Department of Paediatrics, University of Zambia School of Medicine, Lusaka, ZambiaAbstract: With the advent of antiretroviral therapy, remarkable progress has been made in the reduction of morbidity and mortality associated with the human immunodeficiency virus (HIV. As a result, in both the developed and developing world, reproductive decision-making and family planning has re-emerged as an important health issue among HIV-seroconcordant and -serodiscordant couples. This study sought to explore contraceptive attitudes and practices among HIV-seropositive and -serodiscordant couples in the US and Zambia and to compare contraceptive decision-making between seroconcordant and discordant couples. Study results suggest that while most participants expressed a willingness to use protection to prevent pregnancy, the majority were not using protection consistently. Similarly, among seropositive younger men in both the US and Zambia, more men expressed a desire to have children than women of either serostatus group. Study outcomes also suggest that male and female condom use to reduce HIV transmission within couples is limited. Thus, as males are largely the sexual decision makers regarding condom use, women’s attitudes or plans regarding child bearing may be eclipsed by those of their male partners, and recent reductions in provision of female condoms in the developing world may further reduce women’s options to protect themselves and prevent pregnancy. Education and counseling on vertical and horizontal transmission of HIV among both seropositive and serodiscordant couples should be an element of family planning efforts. Conversely, family planning should be a critical element of HIV counseling and testing strategies to

  7. Antileishmanial effect of silver nanoparticles and their enhanced antiparasitic activity under ultraviolet light

    Directory of Open Access Journals (Sweden)

    Allahverdiyev AM

    2011-11-01

    Full Text Available Adil M Allahverdiyev1, Emrah Sefik Abamor1, Malahat Bagirova1, Cem B Ustundag2, Cengiz Kaya2, Figen Kaya2, Miriam Rafailovich3 1Department of Bioengineering; 2Department of Metallurgical and Materials Engineering, Yildiz Technical University, Esenler, Istanbul, Turkey; 3Department of Materials Science and Engineering, Stony Brook University, Stony Brook, NY, USA Abstract: Leishmaniasis is a protozoan vector-borne disease and is one of the biggest health problems of the world. Antileishmanial drugs have disadvantages such as toxicity and the recent development of resistance. One of the best-known mechanisms of the antibacterial effects of silver nanoparticles (Ag-NPs is the production of reactive oxygen species to which Leishmania parasites are very sensitive. So far no information about the effects of Ag-NPs on Leishmania tropica parasites, the causative agent of leishmaniasis, exists in the literature. The aim of this study was to investigate the effects of Ag-NPs on biological parameters of L. tropica such as morphology, metabolic activity, proliferation, infectivity, and survival in host cells, in vitro. Consequently, parasite morphology and infectivity were impaired in comparison with the control. Also, enhanced effects of Ag-NPs were demonstrated on the morphology and infectivity of parasites under ultraviolet (UV light. Ag-NPs demonstrated significant antileishmanial effects by inhibiting the proliferation and metabolic activity of promastigotes by 1.5- to threefold, respectively, in the dark, and 2- to 6.5-fold, respectively, under UV light. Of note, Ag-NPs inhibited the survival of amastigotes in host cells, and this effect was more significant in the presence of UV light. Thus, for the first time the antileishmanial effects of Ag-NPs on L. tropica parasites were demonstrated along with the enhanced antimicrobial activity of Ag-NPs under UV light. Determination of the antileishmanial effects of Ag-NPs is very important for the further

  8. The relationship of psychosocial factors to mammograms, physical activity, and fruit and vegetable consumption among sisters of breast cancer patients

    Directory of Open Access Journals (Sweden)

    Hartman SJ

    2011-08-01

    Full Text Available Sheri J Hartman1, Shira I Dunsiger1, Paul B Jacobsen21Centers for Behavioral and Preventive Medicine, The Miriam Hospital and W Alpert Medical School of Brown University, Providence, RI; 2Department of Health Outcomes and Behavior, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USAAbstract: This study examined the relationship of psychosocial factors to health-promoting behaviors in sisters of breast cancer patients. One hundred and twenty sisters of breast cancer patients completed questionnaires assessing response efficacy of mammography screenings, physical activity, and fruit and vegetable consumption on decreasing breast cancer risk, breast cancer worry, involvement in their sister’s cancer care, mammography screenings, physical activity, and fruit and vegetable consumption. Results indicate that greater perceived effectiveness for mammograms was associated with a 67% increase in odds of yearly mammograms. Greater involvement in the patient’s care was associated with a 7% decrease in odds of yearly mammograms. Greater perceived effectiveness for physical activity was significantly related to greater physical activity. There was a trend for greater perceived effectiveness for fruits and vegetables to be associated with consuming more fruits and vegetables. Breast cancer worry was not significantly associated with the outcomes. While perceived effectiveness for a specific health behavior in reducing breast cancer risk was consistently related to engaging in that health behavior, women reported significantly lower perceived effectiveness for physical activity and fruits and vegetables than for mammograms. Making women aware of the health benefits of these behaviors may be important in promoting changes.Keywords: breast cancer risk, mammograms, physical activity, diet, perceived effectiveness

  9. Exploring synergistic effects of aerobic exercise and mindfulness training on cognitive function in older adults: Protocol for a pilot randomized controlled trial.

    Science.gov (United States)

    Salmoirago-Blotcher, Elena; DeCosta, Julie; Harris, Kristie; Breault, Christopher; Dunsiger, Shira; Santos, Claudia; Snyder, Peter

    2018-05-01

    Despite increasing evidence that aerobic exercise and cognitive training improve cognitive function among patients with cognitive impairment and dementia, few studies have focused on the effect of a combination of these approaches. This study will explore whether combining aerobic training (AT) with mindfulness training (MT), an intervention promoting the moment-to-moment awareness of physical sensations, affective states, and thoughts, improves cognitive function in individuals at risk of dementia. The primary objective is to determine the feasibility and acceptability of the intervention(s). The secondary objective is to obtain estimates of effect sizes on cognitive function and on possible mediators. Forty participants with at least 2 risk factors for dementia will be randomized (2 × 2 factorial design) to either AT (3 sessions/week for 12 weeks), MT (1 session/week for 8 weeks), both, or usual care. Assessments of cognitive function (attention, executive function, episodic, and working memory); physical activity (accelerometry), aerobic capacity (6-minute walk test), waist-to-hip ratio, blood pressure, social support (Multidimensional Scale of Perceived Social Support), depression (Hospital Anxiety and Depression Scale), and mindfulness (Five Facets of Mindfulness) will be conducted at baseline, end of treatment, and 6-months postbaseline. Rates of retention, attendance, and program satisfaction will be calculated for each of the 4 groups to determine the feasibility and acceptability of each intervention. This study has full ethical approval by The Miriam Hospital Institutional Review Board and adheres to the Standard Protocol Items: Recommendations for Interventional Trials reporting recommendations. If results from this exploratory, proof-of-concept study support our hypotheses, we will conduct a large randomized controlled trial (RCT) to determine the efficacy of combined MT and AT in improving cognitive function in individuals at risk of dementia

  10. Drug use trajectory patterns among older drug users

    Directory of Open Access Journals (Sweden)

    Tyndall B

    2011-05-01

    Full Text Available Miriam Boeri, Thor Whalen, Benjamin Tyndall, Ellen BallardKennesaw State University, Department of Sociology and Criminal Justice, Kennesaw GA, USAAbstract: To better understand patterns of drug use trajectories over time, it is essential to have standard measures of change. Our goal here is to introduce measures we developed to quantify change in drug use behaviors. A secondary goal is to provide effective visualizations of these trajectories for applied use. We analyzed data from a sample of 92 older drug users (ages 45 to 65 to identify transition patterns in drug use trajectories across the life course. Data were collected for every year since birth using a mixed methods design. The community-drawn sample of active and former users were 40% female, 50% African American, and 60% reporting some college or greater. Their life histories provided retrospective longitudinal data on the diversity of paths taken throughout the life course and changes in drug use patterns that occurred over time. Bayesian analysis was used to model drug trajectories displayed by innovative computer graphics. The mathematical techniques and visualizations presented here provide the foundation for future models using Bayesian analysis. In this paper we introduce the concepts of transition counts, transition rates and relapse/remission rates, and we describe how these measures can help us better understand drug use trajectories. Depicted through these visual tools, measurements of discontinuous patterns provide a succinct view of individual drug use trajectories. The measures we use on drug use data will be further developed to incorporate contextual influences on the drug trajectory and build predictive models that inform rehabilitation efforts for drug users. Although the measures developed here were conceived to better examine drug use trajectories, the applications of these measures can be used with other longitudinal datasets.Keywords: drug use, trajectory patterns

  11. Fat embolism after fractures in Duchenne muscular dystrophy: an underdiagnosed complication? A systematic review

    Directory of Open Access Journals (Sweden)

    Feder D

    2017-10-01

    Full Text Available David Feder,1 Miriam Eva Koch,1 Beniamino Palmieri,2 Fernando Luiz Affonso Fonseca,1 Alzira Alves de Siqueira Carvalho3 1Pharmacology Department, Faculdade de Medicina do ABC, Santo André, São Paulo, Brazil; 2Department of General Surgery and Surgical Specialties, University of Modena and Reggio Emilia Medical School, Surgical Clinic, Modena, Italy; 3Neuroscience Department, Faculdade de Medicina do ABC, Santo André, São Paulo, Brazil Abstract: Duchenne muscular dystrophy is the most frequent lethal genetic disease. Several clinical trials have established both the beneficial effect of steroids in Duchenne muscular dystrophy and the well-known risk of side effects associated with their daily use. For many years it has been known that steroids associated with ambulation loss lead to obesity and also damage the bone structure resulting in the bone density reduction and increased incidence of bone fractures and fat embolism syndrome, an underdiagnosed complication after fractures. Fat embolism syndrome is characterized by consciousness disturbance, respiratory failure and skin rashes. The use of steroids in Duchenne muscular dystrophy may result in vertebral fractures, even without previous trauma. Approximately 25% of patients with Duchenne muscular dystrophy have a long bone fracture, and 1% to 22% of fractures have a chance to develop fat embolism syndrome. As the patients with Duchenne muscular dystrophy have progressive cardiac and respiratory muscle dysfunction, the fat embolism may be unnoticed clinically and may result in increased risk of death and major complications. Different treatments and prevention measures of fat embolism have been proposed; however, so far, there is no efficient therapy. The prevention, early diagnosis and adequate symptomatic treatment are of paramount importance. The fat embolism syndrome should always be considered in patients with Duchenne muscular dystrophy presenting with fractures, or an unexplained and

  12. Modeling the geochemical distribution of rare earth elements (REEs using multivariate statistics in the eastern part of Marvast placer, the Yazd province

    Directory of Open Access Journals (Sweden)

    Amin Hossein Morshedy

    2017-07-01

    Full Text Available Introduction Nowadays, exploration of rare earth element (REE resources is considered as one of the strategic priorities, which has a special position in the advanced and intelligent industries (Castor and Hedrick, 2006. Significant resources of REEs are found in a wide range of geological settings, including primary deposits associated with igneous and hydrothermal processes (e.g. carbonatite, (per alkaline-igneous rocks, iron-oxide breccia complexes, scarns, fluorapatite veins and pegmatites, and secondary deposits concentrated by sedimentary processes and weathering (e.g. heavy-mineral sand deposits, fluviatile sandstones, unconformity-related uranium deposits, and lignites (Jaireth et al., 2014. Recent studies on various parts of Iran led to the identification of promising potential of these elements, including Central Iran, alkaline rocks in the Eslami Peninsula, iron and apatite in the Hormuz Island, Kahnouj titanium deposit, granitoid bodies in Yazd, Azerbaijan, and Mashhad and associated dikes, and finally placers related to the Shemshak formation in Marvast, Kharanagh, and Ardekan indicate high concentration of REE in magmatogenic iron–apatite deposits in Central Iran and placers in Marvast area in Yazd (Ghorbani, 2013. Materials and methods In the present study, the geochemical behavior of rare earth elements is modeled by using multivariate statistical methods in the eastern part of the Marvast placer. Marvast is located 185 km south of the city of Yazd in central Iran between Yazd and Mehriz. This area lies within the southeastern part of the Sanandaj-Sirjan Zone (Alipour-Asll et al., 2012. The samples of 53 wells were analyzed for Whole-rock trace-element concentrations (including REE by inductively coupled plasma-mass spectrometry (ICP-MS (GSI, 2004. The clustering techniques such as multivariate statistical analysis technique can be employed to find appropriate groups in data sets. One of the main objectives of data clustering

  13. "Façamos dessa gente um elemento seguro do nosso progresso material e moral": a inspeção médico-escolar no Paraná dos anos 1920 Let's make these people a safe element of our material and moral progress: medical-scholar inspections in Paraná during the 1920's

    Directory of Open Access Journals (Sweden)

    Vera Regina Beltrão Marques

    2010-04-01

    Full Text Available A linha norteadora da educação no Paraná está fundamentada na necessidade de recuperar o homem nativo (caboclo enquanto força de trabalho através de seu aperfeiçoamento moral, físico, intelectual e laboral. Requer-se da escola o desempenho desta patriótica missão: formar a inteligência do caboclinho de maneira a conhecer intuitivamente preceitos da higiene, meios de defesa contra os insetos e animais nocivos, vantagens do calçado e do uso de instrumentos aperfeiçoados para maior rendimento do trabalho manual". Com essa escola, as autoridades educacionais acreditaram que a higiene rural encontraria o seu melhor auxiliar. Nossa comunicação discute as propostas de inspeção médico-escolar na gestão de Cezar Prieto Martinez, tendo em vista as singularidades populacionais e os objetivos de nacionalização da escola almejados. Que características e desdobramentos norteiam o discurso médico higienista em face da realidade na qual o embranquecimento não se coloca como questão fundamental?The main axis of Education in Paraná is based on the necessity of retrieving the native man (half-caste as labor force by the development of their moral, physic, intellect and work. This way, it is expected from the school, such patriotic mission: to develop the little native men intelligence in order to make them intuitively aware of "the most appropriate hygiene practices, defensive attitudes against insects and harmful animals, and the advantages of wearing shoes and utilizing improved tools for better handiwork". With such school, educational authorities believed that rural hygiene would find its best supporter. This communication intends to discuss proposals of medical-scholar inspections presented during Cesar Prieto Martinez's public management, taking into consideration the specificities of the population and the objectives of the school nationalization aimed by the State. What characteristics and developments guide medical hygienist

  14. Field, Laboratory and Imaging spectroscopic Analysis of Landslide, Debris Flow and Flood Hazards in Lacustrine, Aeolian and Alluvial Fan Deposits Surrounding the Salton Sea, Southern California

    Science.gov (United States)

    Hubbard, B. E.; Hooper, D. M.; Mars, J. C.

    2015-12-01

    High resolution satellite imagery, field spectral measurements using a portable ASD spectrometer, and 2013 hyperspectral AVIRIS imagery were used to evaluate the age of the Martinez Mountain Landslide (MML) near the Salton Sea, in order to determine the relative ages of adjacent alluvial fan surfaces and the potential for additional landslides, debris flows, and floods. The Salton Sea (SS) occupies a pluvial lake basin, with ancient shorelines ranging from 81 meters to 113 meters above the modern lake level. The highest shoreline overlaps the toe of the 0.24 - 0.38 km3 MML deposit derived from hydrothermally altered granites exposed near the summit of Martinez Mountain. The MML was originally believed to be of early Holocene age. However, AVIRIS mineral maps show abundant desert varnish on the top and toe of the landslide. Desert varnish can provide a means of relative dating of alluvial fan (AF) or landslide surfaces, as it accumulates at determinable rates over time. Based on the 1) highest levels of desert varnish accumulation mapped within the basin, 2) abundant evaporite playa minerals on top of the toe of the landslide, and 3) the highest shoreline of the ancestral lake overtopping the toe of the landslide with gastropod and bivalve shells, we conclude that the MML predates the oldest alluvial fan terraces and lake sediments exposed in the Coachella and Imperial valleys and must be older than early Holocene (i.e. Late Pleistocene?). Thus, the MML landslide has the potential to be used as a spectral endmember for desert varnish thickness and thus proxy for age discrimination of active AF washes versus desert pavements. Given the older age of the MML landslide and low water levels in the modern SS, the risk from future rockslides of this size and related seiches is rather low. However, catastrophic floods and debris flows do occur along the most active AF channels; and the aftermath of such flows can be identified spectrally by montmorillonite crusts forming in

  15. Comparative manufacture and cell-based delivery of antiretroviral nanoformulations

    Directory of Open Access Journals (Sweden)

    Balkundi S

    2011-12-01

    Full Text Available Shantanu Balkundi1, Ari S Nowacek1, Ram S Veerubhotla1, Han Chen2, Andrea Martinez-Skinner1, Upal Roy1, R Lee Mosley1,3, Georgette Kanmogne1, Xinming Liu1,3,4, Alexander V Kabanov3,4, Tatiana Bronich3,4, JoEllyn McMillan1, Howard E Gendelman1,31Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, USA; 2Center for Biotechnology, University of Nebraska-Lincoln, Lincoln, NE, USA; 3Center for Drug Delivery and Nanomedicine, University of Nebraska Medical Center, Omaha, NE, USA; 4Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE, USAAbstract: Nanoformulations of crystalline indinavir, ritonavir, atazanavir, and efavirenz were manufactured by wet milling, homogenization or sonication with a variety of excipients. The chemical, biological, immune, virological, and toxicological properties of these formulations were compared using an established monocyte-derived macrophage scoring indicator system. Measurements of drug uptake, retention, release, and antiretroviral activity demonstrated differences amongst preparation methods. Interestingly, for drug cell targeting and antiretroviral responses the most significant difference among the particles was the drug itself. We posit that the choice of drug and formulation composition may ultimately affect clinical utility.Keywords: human immunodeficiency virus type one, nanotoxicology, monocyte-derived macrophage, nanoformulated antiretroviral therapy, manufacturing techniques

  16. Gabriel Miró, Del vivir (1904 y su ruptura con la convención novelesca

    Directory of Open Access Journals (Sweden)

    Lozano Marco, Miguel Ángel

    2005-12-01

    Full Text Available I'm trying to analyze, with our new criteria, Del vivir, the first work recognized by Gabriel Miró as his, after repudiating his two previous novels. The proposal, documented, of the writing date allows venturing one hypothesis: the influence that Antonio Azorin could exercise over the young Miró. The novelistic model found in the Jose Martinez Ruiz work teaches him to disregard the argument in order to attend to the life, and allows him to conceive a character (whom we only know that his name is Sigüenza without neither physical features nor story, in order to emphasize its substance and moral nature.Pretendo analizar, con nuevos criterios, Del vivir, la primera obra que Gabriel Miró reconoce como suya después de repudiar sus dos novelas anteriores. La propuesta, documentada, de la fecha de escritura permite aventurar una hipótesis: la influencia que Antonio Azorín pudo ejercer sobre el joven Miró. El modelo novelístico que encuentra en la obra de José Martínez Ruiz le enseña a prescindir del argumento para atender a la vida, y le permite concebir un personaje (del que sólo sabemos que se llama Sigüenza sin rasgos físicos y sin historia, para destacar su sustancia y carácter moral.

  17. Assessment of bioavailability of weathered oil residues using caged bivalves (Crassostrea gigas and Mytilus edulis) as indicator organisms

    International Nuclear Information System (INIS)

    Bleczinski, C.F.; Costa, H.J.; Rigatti, M.J.; Wong, M.C.; Boehm, P.D.

    1993-01-01

    In April 1988, an estimated 400,000 gallons of San Joaquin Valley crude oil spilled into Peyton Slough and subsequently into Suisun Bay from an oil refinery in Martinez, California. The crude oil initially impacted a number of ecologically sensitive environments including estuarine water, marsh grasses, marsh and shoreline sediment, and intertidal sediment. A four-year oil weathering study was performed to determine the concentrations of environmentally important compounds in the stranded oil, to monitor changes in these concentrations over time, and to assess the potential long-term impact of the spilled oil in these various environments. As a result of marked differences in the rate of weathering at the different sites, a bioaccumulation component was added to the original study design in order to assess the bioavailability of crude oil residues remaining four-years post spill. Caged bivalves (Crassostrea gigas and Mytilus edulis) were deployed at the three study sites as sentinel organisms and exposed for three months. Sediments and organism tissues were analyzed using gas chromatography/mass spectrometry for polynuclear aromatic hydrocarbon (PAH) assemblages characteristics of the spilled oil. Advanced hydrocarbon fingerprinting techniques (e.g., double ratio plots of characteristic alkyl PAHs) were used to match distributions in the organisms and in the study site sediments

  18. Atomic orbital-based SOS-MP2 with tensor hypercontraction. II. Local tensor hypercontraction

    Science.gov (United States)

    Song, Chenchen; Martínez, Todd J.

    2017-01-01

    In the first paper of the series [Paper I, C. Song and T. J. Martinez, J. Chem. Phys. 144, 174111 (2016)], we showed how tensor-hypercontracted (THC) SOS-MP2 could be accelerated by exploiting sparsity in the atomic orbitals and using graphical processing units (GPUs). This reduced the formal scaling of the SOS-MP2 energy calculation to cubic with respect to system size. The computational bottleneck then becomes the THC metric matrix inversion, which scales cubically with a large prefactor. In this work, the local THC approximation is proposed to reduce the computational cost of inverting the THC metric matrix to linear scaling with respect to molecular size. By doing so, we have removed the primary bottleneck to THC-SOS-MP2 calculations on large molecules with O(1000) atoms. The errors introduced by the local THC approximation are less than 0.6 kcal/mol for molecules with up to 200 atoms and 3300 basis functions. Together with the graphical processing unit techniques and locality-exploiting approaches introduced in previous work, the scaled opposite spin MP2 (SOS-MP2) calculations exhibit O(N2.5) scaling in practice up to 10 000 basis functions. The new algorithms make it feasible to carry out SOS-MP2 calculations on small proteins like ubiquitin (1231 atoms/10 294 atomic basis functions) on a single node in less than a day.

  19. Use of storage substance in garlic propagules irradiated of gamma rays

    International Nuclear Information System (INIS)

    Perez Talavera, S.; Lopez Cervantes, M.; Perez Lezcano, A.

    1997-01-01

    Gamma radioinduced effects on different growth indicators and the destination of storage substances of cloves were investigated in garlic cv. Martinez. To this purpose, the doses interval of its radiosensitivity curve was considered. Within the Gr 10-20 (growth reduction) interval there was no damage or if was small in growth indicators and also leaves width was stimulated, enabling to each leave areas similar to those of testing plants. In addition significant increases of storage compounds use in cloves were observed. This result may be interpreted as an additional energetic consumption to repair radiation damage. Behaviour starting at Gr 30 may be critical because plants undergo severe damage in most of the analyzed indicators principally those that depend of leaves area. This result. from a physiological point of view, complement the recommendation of selecting doses in Gr 10-20 interval for the radio mutagenesis works, recommendation made in base of small lethality and sterility, and high percentage of useful mutation reported for this doses interval

  20. Descripción histórica de la Institución Educativa Fulgencio Lequerica Vélez de la ciudad de Cartagena de Indias

    Directory of Open Access Journals (Sweden)

    Dioselina Iriarte Barbosa

    2015-10-01

    Full Text Available La Institución Educativa Fulgencio Lequerica Vélez nació de la necesidad de ubicar a los hijos de las familias del sector tugurial de Chambacú, los cuales habían sido trasladados al barrio de Chiquinquirá en el año 1976. La Institución se caracteriza por presentar un contexto escolar donde pulula la situación de pobreza y de extrema vulnerabilidad. La Institución debe su nombre al padre del ex representante a la Cámara doctor Antonio Lequerica Martínez, quien en el año 1976 autorizó la creación de este colegio colocándole, en honor a su padre, el nombre de Fulgencio Lequerica Vélez.AbstractThe Educational Institute Fulgencio Lequerica Vélez was born out of the necessity to provide homes to the families that lived in the slums of the urban area of Chambacú, which had been transferred to the area of Chiquinquirá in 1.976.The institution is characterized for presenting an educational context where poverty is the plenty and of extreme vulnerability. The institution owes its name to the father of Congressman Dr. Antonio Lequerica Martinez,who in year 1976 authorized the creation of this school,naming it after his father Antonio Lequerica Velez

  1. Monogeneans of freshwater fishes from cenotes (sinkholes) of the Yucatan Peninsula, Mexico.

    Science.gov (United States)

    Mendoza-Franco, E F; Scholz, T; Vivas-Rodríguez, C; Vargas-Vázquez, J

    1999-01-01

    During a survey of the parasites of freshwater fishes from cenotes (sinkholes) of the Yucatan Peninsula the following species of monogeneans were found on cichlid, pimelodid, characid and poeciliid fishes: Sciadicleithrum mexicanum Kritsky, Vidal-Martinez et Rodriguez-Canul, 1994 from Cichlasoma urophthalmus (Günther) (type host), Cichlasoma friedrichsthali (Heckel), Cichlasoma octofasciatum (Regan), and Cichlasoma synspilum Hubbs, all new host records; Sciadicleithrum meekii Mendoza-Franco, Scholz et Vidal-Martínez, 1997 from Cichlasoma meeki (Brind); Urocleidoides chavarriai (Price, 1938) and Urocleidoides travassosi (Price, 1938) from Rhamdia guatemalensis (Günther); Urocleidoides costaricensis (Price et Bussing, 1967), Urocleidoides heteroancistrium (Price et Bussing, 1968), Urocleidoides anops Kritsky et Thatcher, 1974, Anacanthocotyle anacanthocotyle Kritsky et Fritts, 1970, and Gyrodactylus neotropicalis Kritsky et Fritts, 1970 from Astyanax fasciatus; and Gyrodactylus sp. from Gambusia yucatana Regan. Urocleidoides chavarriai, U. travassosi, U. costaricensis, U. heteroancistrium, U. anops, Anacanthocotyle anacanthocotyle and Gyrodactylus neotropicalis are reported from North America (Mexico) for the first time. These findings support the idea about the dispersion of freshwater fishes and their monogenean parasites from South America through Central America to southeastern Mexico, following the emergence of the Panamanian isthmus between 2 and 5 million years ago.

  2. SEDAH. Data Server for hydrologic alteration evaluation

    International Nuclear Information System (INIS)

    Martinez Romero, R.; Magdaleno Mas, F.; Ortiz Rodriguez, J.; Fernandez Yuste, J. A.; Martinez Santa-Maria, C.

    2011-01-01

    Several tasks and studies have been developed from 2008 till 2010 all around the country in order to evaluate the hydrologic alteration of water bodies. In most cases this alteraction has been evaluated through IAHRIS (Martinez and Fernandez, 2006). The necessity of creating a new toll that allowed a better performance of the National Flow-Stage Stations Network data was showed up by developing these works. The output data series should match IAHRIS and IHA. SEDAH (Data Server for Evaluating Hydrologic Alteration) Helps to solve some of these problems by supplying an easy way to select flow stations, dates, flow series typology, etc. Moreover, other useful utilities are: a preliminary appraisement of quality data, calssification of altered or reference flow series and exportation of data in different file formats. The web application works with different data bases, daily, monthly and annual series belonging to, wither actual series from flow station data or completed series by statistical procedures. Through SEDAH the user has easy access to all this huge information ready for being applied in hydrologic alteration assessment, environmental fows regime, river restoration projects, etc. Furthermore, this first phase of the application constitute the basis for future powerful functionalities related to the natural flow series obtaining. (Author) 5 refs.

  3. SEDAH. Data Server for hydrologic alteration evaluation; SEDAH: Servidor de datos para el estudio de la alteracion hidrologica

    Energy Technology Data Exchange (ETDEWEB)

    Martinez Romero, R.; Magdaleno Mas, F.; Ortiz Rodriguez, J.; Fernandez Yuste, J. A.; Martinez Santa-Maria, C.

    2011-07-01

    Several tasks and studies have been developed from 2008 till 2010 all around the country in order to evaluate the hydrologic alteration of water bodies. In most cases this alteration has been evaluated through IAHRIS (Martinez and Fernandez, 2006). The necessity of creating a new toll that allowed a better performance of the National Flow-Stage Stations Network data was showed up by developing these works. The output data series should match IAHRIS and IHA. SEDAH (Data Server for Evaluating Hydrologic Alteration) Helps to solve some of these problems by supplying an easy way to select flow stations, dates, flow series typology, etc. Moreover, other useful utilities are: a preliminary appraisement of quality data, classification of altered or reference flow series and exportation of data in different file formats. The web application works with different data bases, daily, monthly and annual series belonging to, wither actual series from flow station data or completed series by statistical procedures. Through SEDAH the user has easy access to all this huge information ready for being applied in hydrologic alteration assessment, environmental flows regime, river restoration projects, etc. Furthermore, this first phase of the application constitute the basis for future powerful functionalities related to the natural flow series obtaining. (Author) 5 refs.

  4. Quaternion analysis of generalized electromagnetic fields in chiral media

    International Nuclear Information System (INIS)

    Bisht, P. S. . Email. ps_bisht123@rediffmail.com

    2007-01-01

    The time dependent Maxwell's equations in presence of electric and magnetic charges has been developed in chiral media and the solutions for the classical problem are obtained in unique, simple and consistent manner. The quaternionic reformulation of generalized electromagnetic fields in chiral media has also been developed in compact and consistent way. Simulation of neutron backscattering process applied to organic material detection. Forero Martinez, Nancy Carolina; Cristancho, Fernando (Nuclear Physics Group, Universidad Nacional de Colombia, Bogota D.C. (Colombia)) Abstract Atomic and nuclear physics based sensors might offer new possibilities in de-mining. There is a particular interest in the possibility of using neutrons for the non-intrusive detection of hidden contraband, explosives or illicit drugs. The Neutron Backscattering Technique, based on the detection of the produced thermal neutrons, is known to be a useful tool to detect hidden explosives which present an elevated concentration of light elements (H, C, N, O). In this way we present the simulated results using the program package Geant4. Different variables were modified including the soil composition and the studied materials. (Author)

  5. Real-Time Monitoring of Neutron Capture Cross Section in the IPR-R1 TRIGA Research Reactor as a Fuel Temperature Function

    Energy Technology Data Exchange (ETDEWEB)

    Palma, D.A.P. [Comissao Nacional de Energia Nuclear, CNEN, General Severiano Street, 90, 22290-901, Rio de Janeiro (Brazil); Mesquita, A.Z.; Souza, R.M.G.P. [Comissao Nacional de Energia Nuclear, CNEN/CDTN, Av. Presidente Antonio Carlos, 6627, 31270-901, Belo Horizonte (Brazil); Martinez, A.S. [Programa de Engenharia Nuclear, COPPE/UFRJ, Av. Horacio Macedo, 2030, Bloco G, 21941- 914, Rio de Janeiro (Brazil)

    2011-07-01

    Nuclear reactor operators have to monitor the behaviour of different nuclear and design parameters that vary in time to ensure the operating safety of the reactor. In recent years several operating parameters for the IPR-R1 TRIGA research reactor were monitored and indicated in real-time by the data acquisition system developed for the reactor, with all the data being stored in a hard disk in the data acquisition computer, to build in this way a database. The goal of this work is to insert in the set of parameters already collected the neutron capture cross sections for the fuel, from the power and temperature numbers obtained in real-time. The experimental data was obtained by using a fuel element instrumented with temperature sensors, located in the core of the IPR-R1 TRIGA research reactor at the CDTN - Centre for Development of Nuclear. This information is useful for the continuous monitoring of the reaction rate in neutron capture. For that, a new analytical formulation is used for the Doppler broadening function proposed by Palma and Martinez which is free from special functions in its functional form and with easy computing implementation. The results obtained were satisfactory from the standpoint of accuracy in comparison with the numerical reference method and indicate that it is possible to carry out real-time monitoring of the neutron capture cross section in the fuel. (author)

  6. Le Petit Robert dictionnaire alphabétique et analogique de la langue française

    CERN Document Server

    Rey, Alain

    2014-01-01

    60 000 mots, 300 000 sens 35 000, citations. Retrouvez le français vivant, les mots et expressions d'aujourd'hui : astroparticule, biothèque, caméo, clivant, coltan, dim sum, fadette, itinérance, locavore, microbiote, modeux, street art, transgénérationnel ...Vérifiez l'usage de chaque mot : l'orthographe, la prononciation, les nuances de sens, les homonymes. Découvrez l'histoire des mots et leur étymologie Passez d'une idée à l'autre, allez du connu vers l'inconnu, en suivant les liens entre les mots : synonymes, analogies, contraires... Rencontrez les auteurs classiques et contemporains, par leurs citations : Olivier Adam, Emmanuel Carrère, Jean Echenoz, Annie Ernaux, Alice Ferney, Le Clézio, Carole Martinez, Patrick Modiano, Marie NDiaye, Amélie Nothomb, Daniel Pennac, Pascal Quignard, Michel Tournier, Michel Tremblay, Delphine de Vigan ... Voyagez dans la francophonie et partez à la découverte de ses richesses.

  7. Accurate transport simulation of electron tracks in the energy range 1 keV-4 MeV

    International Nuclear Information System (INIS)

    Cobut, V.; Cirioni, L.; Patau, J.P.

    2004-01-01

    Multipurpose electron transport simulation codes are widely used in the fields of radiation protection and dosimetry. Broadly based on multiple scattering theories and continuous energy loss stopping powers with some mechanism taking straggling into account, they give reliable answers to many problems. However they may be unsuitable in some specific situations. In fact, many of them are not able to accurately describe particle transport through very thin slabs and/or in high atomic number materials, or also when knowledge of high-resolution depth dose distributions is required. To circumvent these deficiencies, we developed a Monte Carlo code simulating each interaction along electron tracks. Gas phase elastic cross sections are corrected to take into account solid state effects. Inelastic interactions are described within the framework of the Martinez et al. [J. Appl. Phys. 67 (1990) 2955] theory intended to deal with energy deposition in both condensed insulators and conductors. The model described in this paper is validated for some materials as aluminium and silicon, encountered in spectrometric and dosimetric devices. Comparisons with experimental, theoretical and other simulation results are made for angular distributions and energy spectra of transmitted electrons through slabs of different thicknesses and for depth energy distributions in semi-infinite media. These comparisons are quite satisfactory

  8. Davras Dagı (Isparta ve Çevresinin Orman ve Çalı Vejetasyonu

    Directory of Open Access Journals (Sweden)

    Coşkun SAĞLAM

    2009-04-01

    Full Text Available Bu vejetasyon çalısması, 2002-2005 yılları arasında Batı Toroslar'da yer alan Davras Dagı ve çevresinde gerçeklestirildi. Vejetasyon Braun-Blanquet (1964 metoduna göre analiz edilerek orman ve çalı vejetasyonuna ait yedi birlik tespit edildi. Bunlardan bes tanesi yenidir. Orman vejetasyonu: Sınıf : Quercetea pubescentis (Oberd, 1948 Doing Kraft, 1955 Ordo : Querco – Cedretalia libani Barbéro, Loisel ve Quézel, 1974 1. Minuartio globulosi – Juniperetum excelsae ass. nova 2. Sileno squamigeri – Quercetum cerridis ass. nova 3. Astragalo oxytropifolii – Pinetum caramanicae ass. nova Alyans : Lonicero nummulariaefoliae – Cedrion libani Quézel, Barbéro ve Akman 1978 4. Veronico syriaci – Cedretum libani ass. nova 5. Diantho cibrarii – Quercetum vulcanicae Kurt et al. 1996 Sınıf : Quercetea ilicis Br.-Bl., 1947 Ordo : Quercetalia ilicis Br.-Bl., 1947, Rivaz Martinez, 1974 Alyans : Quercion cocciferae Quézel, Barbéro, Akman, 1978 6. Hyperico polyphylli – Pinetum brutiae ass. nova Çalı Vejetasyonu: Sınıf : Quercetea pubescentis (Oberd, 1948 Doing Kraft, 1955 Ordo : Querco – Cedretalia libani Barbéro, Loisel ve Quézel, 1974 7. Astragalo atropurpureus– Quercetum cocciferae Kargıoglu, 19

  9. New charged black holes with conformal scalar hair

    International Nuclear Information System (INIS)

    Anabalon, Andres; Maeda, Hideki

    2010-01-01

    A new class of four-dimensional, hairy, stationary solutions of the Einstein-Maxwell-Λ system with a conformally coupled scalar field is obtained. The metric belongs to the Plebanski-Demianski family and hence its static limit has the form of the charged (A)dS C metric. It is shown that, in the static case, a new family of hairy black holes arises. They turn out to be cohomogeneity-two, with horizons that are neither Einstein nor homogenous manifolds. The conical singularities in the C metric can be removed due to the backreaction of the scalar field providing a new kind of regular, radiative spacetime. The scalar field carries a continuous parameter proportional to the usual acceleration present in the C metric. In the zero-acceleration limit, the static solution reduces to the dyonic Bocharova-Bronnikov-Melnikov-Bekenstein solution or the dyonic extension of the Martinez-Troncoso-Zanelli black holes, depending on the value of the cosmological constant.

  10. Dilemma in the emergency setting: hypomagnesemia mimicking acute stroke

    Directory of Open Access Journals (Sweden)

    Rico M

    2016-06-01

    Full Text Available María Rico, Laura Martinez-Rodriguez, Davinia Larrosa-Campo, Sergio Calleja Neurology Department, Central University Hospital of Asturias, Oviedo, Spain Background: Stroke mimics may account for up to 30% of all acute stroke consultations. However, in the emergency setting, accurate diagnosis is not always possible.Methods: Case report and review of the literature.Results: A 73-year-old woman was admitted to the emergency department with acute aphasia and right hemiparesis. The National Institute of Health Stroke Score was 21, compatible with severe stroke, so she received thrombolysis. Laboratory testing demonstrated severe hypomagnesemia. She had been taking proton pump inhibitors for years and neuroimaging did not demonstrate signs of acute ischemic disease. After correcting the metabolic alterations with intravenous and oral supplemental magnesium, the patient was discharged asymptomatic. No further episodes have been registered to date.Conclusion: Hypomagnesemia might cause acute neurological symptoms that could be confused with stroke. A careful history is essential for diagnosis but suspicion of stroke mimic should not prevent tPA administration. Keywords: hypomagnesemia, stroke mimic, aphasia, stroke

  11. Molecular Phylogeny and Revision of Copepod Orders (Crustacea: Copepoda).

    Science.gov (United States)

    Khodami, Sahar; McArthur, J Vaun; Blanco-Bercial, Leocadio; Martinez Arbizu, Pedro

    2017-08-22

    For the first time, the phylogenetic relationships between representatives of all 10 copepod orders have been investigated using 28S and 18S rRNA, Histone H3 protein and COI mtDNA. The monophyly of Copepoda (including Platycopioida Fosshagen, 1985) is demonstrated for the first time using molecular data. Maxillopoda is rejected, as it is a polyphyletic group. The monophyly of the major subgroups of Copepoda, including Progymnoplea Lang, 1948 (=Platycopioida); Neocopepoda Huys and Boxshall, 1991; Gymnoplea Giesbrecht, 1892 (=Calanoida Sars, 1903); and Podoplea Giesbrecht, 1892, are supported in this study. Seven copepod orders are monophyletic, including Platycopioida, Calanoida, Misophrioida Gurney, 1933; Monstrilloida Sars, 1901; Siphonostomatoida Burmeister, 1834; Gelyelloida Huys, 1988; and Mormonilloida Boxshall, 1979. Misophrioida (=Propodoplea Lang, 1948) is the most basal Podoplean order. The order Cyclopoida Burmeister, 1835, is paraphyletic and now encompasses Poecilostomatoida Thorell, 1859, as a sister to the family Schminkepinellidae Martinez Arbizu, 2006. Within Harpacticoida Sars, 1903, both sections, Polyarthra Lang, 1948, and Oligoarthra Lang, 1948, are monophyletic, but not sister groups. The order Canuelloida is proposed while maintaining the order Harpacticoida s. str. (Oligoarthra). Cyclopoida, Harpacticoida and Cyclopinidae are redefined, while Canuelloida ordo. nov., Smirnovipinidae fam. nov. and Cyclopicinidae fam. nov are proposed as new taxa.

  12. Progress on the artificial rearing of Anastrepha fraterculus (Wied.) (Diptera: Tephritidae) in Colombia

    International Nuclear Information System (INIS)

    Nunez Bueno, L.; Guzman Duenas, R.

    1999-01-01

    With the purpose of evaluating post-harvest quarantine treatments for fruits in Colombia, we have established experimental colonies of fruit flies (Diptera: Tephritidae) at the Colombian Agricultural Institute (ICA), plant quarantine Laboratory Ibague (Tol.) at 24 deg. C, 70-80% RH, and 10 hr light. The procedures and results refer only to A. fraterculus from September 1994 to September 1996. The first adults, obtained from Coffea arabica L. cherries, were initially multiplied in fruits and later put on artificial diet. The handling procedures, diets and data collected are adapted from those established by USDA-ARA 1981, Celedonio et al. 1989, Gonzalez et al. Martinez et al. 1987, and others, that were used for Anastrepha spp. The average percentages of recuperation between stages that were hatched 66.0±1.0; first to third instar larvae 28.12±14.4; third instar larvae to pupae 81.80±3.0; pupae to adult 75.82±3.4. Additional data related to partial mortality of the stages are also discussed. The average recuperation from eggs to third instar larvae of 17.57%, and from eggs to emerged adults of 9.5±4.9, is low and indicates the necessity of doing basic research to improve the procedures. (author)

  13. Biscrolling nanotube sheets and functional guests into yarns

    Science.gov (United States)

    Baughman, Ray

    2011-03-01

    Multifunctional applications of textiles have been limited by the inability to spin important materials into yarns. Generically applicable methods are demonstrated for producing weavable yarns comprising up to 95 wt % of otherwise unspinnable particulate or nanofiber powders that remain highly functional. Scrolled 50 nm thick carbon nanotube sheets confine these powders in the galleries of irregular scroll sacks, whose observed complex structures are related to twist-dependent extension of Archimedean spirals, Fermat spirals, or spiral pairs into scrolls. The strength and electronic connectivity of a small weight fraction of scrolled carbon nanotube sheet enables yarn weaving, sewing, knotting, braiding, and charge collection. This technology is used to make yarns of superconductors, Li-ion battery materials, graphene ribbons, catalytic nanofibers for fuel cells, and Ti O2 for photocatalysis. Work done in collaboration with Shaoli Fang, Xavier Lepro-Chavez, Chihye Lewis, Raquel Ovalle-Robles, Javier Carratero-Gonzalez, Elisabet Castillo-Martinez, Mikhail Kozlov, Jiyoung Oh, Neema Rawat, Carter Haines, Mohammed Haque, Vaishnavi Aare, Stephanie Stoughton, Anvar Zakhidov, and Ray Baughman, The University of Texas at Dallas / Alan G. MacDiarmid NanoTech Institute.

  14. Kinetic Study of the Aroxyl-Radical-Scavenging Activity of Five Fatty Acid Esters and Six Carotenoids in Toluene Solution: Structure-Activity Relationship for the Hydrogen Abstraction Reaction.

    Science.gov (United States)

    Mukai, Kazuo; Yoshimoto, Maya; Ishikura, Masaharu; Nagaoka, Shin-Ichi

    2017-08-17

    A kinetic study of the reaction between an aroxyl radical (ArO • ) and fatty acid esters (LHs 1-5, ethyl stearate 1, ethyl oleate 2, ethyl linoleate 3, ethyl linolenate 4, and ethyl arachidonate 5) has been undertaken. The second-order rate constants (k s ) for the reaction of ArO • with LHs 1-5 in toluene at 25.0 °C have been determined spectrophotometrically. The k s values obtained increased in the order of LH 1 LHs 1-5. The k s value for LH 5 was 2.93 × 10 -3 M -1 s -1 . From the result, it has been clarified that the reaction of ArO • with LHs 1-5 was explained by an allylic hydrogen abstraction reaction. A similar kinetic study was performed for the reaction of ArO • with six carotenoids (Car-Hs 1-6, astaxanthin 1, β-carotene 2, lycopene 3, capsanthin 4, zeaxanthin 5, and lutein 6). The k s values obtained increased in the order of Car-H 1 LHs 1-5. The results of detailed analyses of the k s values for the above reaction indicated that the reaction was also explained by an allylic hydrogen abstraction reaction. Furthermore, the structure-activity relationship for the reaction was discussed by taking the result of density functional theory calculation reported by Martinez and Barbosa into account.

  15. Reviews of recent publications

    Directory of Open Access Journals (Sweden)

    2001-06-01

    Full Text Available Alonso, Carlos J. The Burden of Modernity: The Rhetoric of Cultural Discourse in Spanish America Reviewed by Melvin S. Arrington, Jr. Kolocotroni, Vassiliki, Jane Goldman, and Olga Taxidou, eds, Modernism: An Anthology of Sources and Documents Reviewed by Gerd Bayer Motte, Warren. Small Worlds: Minimalism in Contemporary French Literature Reviewed by William Cloonan Melton, Judith M. The Face of Exile: Autobiographical Journeys Reviewed by Claude P. Desmarais Redding, Arthur. Raids on Human Consciousness: Writing, Anarchism, and Violence Reviewed by Gail Finney Chambers, Ross. Facing It: AIDS Diaries and the Death of the Author Reviewed by Melissa A. Fitch Marx-Scouras, Danielle. The Cultural Politics of Tel Quel: Literature and the Left in the Wake of Engagement Reviewed by Diane Fourny Foster, David William. Buenos Aires: Perspectives on the City and Cultural Production Reviewed by Gustavo Geirola Nelson, Ardis L., ed. Guillermo Cabrera Infante: Assays, essays, and other arts Reviewed by José Luis Martinez-Dueñas Fox, Claire F. The Fence and the River: Culture and Politics at the U.S.-Mexico Border Reviewed by Robert Neustadt

  16. U(1) Wilson lattice gauge theories in digital quantum simulators

    Science.gov (United States)

    Muschik, Christine; Heyl, Markus; Martinez, Esteban; Monz, Thomas; Schindler, Philipp; Vogell, Berit; Dalmonte, Marcello; Hauke, Philipp; Blatt, Rainer; Zoller, Peter

    2017-10-01

    Lattice gauge theories describe fundamental phenomena in nature, but calculating their real-time dynamics on classical computers is notoriously difficult. In a recent publication (Martinez et al 2016 Nature 534 516), we proposed and experimentally demonstrated a digital quantum simulation of the paradigmatic Schwinger model, a U(1)-Wilson lattice gauge theory describing the interplay between fermionic matter and gauge bosons. Here, we provide a detailed theoretical analysis of the performance and the potential of this protocol. Our strategy is based on analytically integrating out the gauge bosons, which preserves exact gauge invariance but results in complicated long-range interactions between the matter fields. Trapped-ion platforms are naturally suited to implementing these interactions, allowing for an efficient quantum simulation of the model, with a number of gate operations that scales polynomially with system size. Employing numerical simulations, we illustrate that relevant phenomena can be observed in larger experimental systems, using as an example the production of particle-antiparticle pairs after a quantum quench. We investigate theoretically the robustness of the scheme towards generic error sources, and show that near-future experiments can reach regimes where finite-size effects are insignificant. We also discuss the challenges in quantum simulating the continuum limit of the theory. Using our scheme, fundamental phenomena of lattice gauge theories can be probed using a broad set of experimentally accessible observables, including the entanglement entropy and the vacuum persistence amplitude.

  17. Methodology to evaluate the impact of the erosion in cultivated floors applying the technique of the 137CS

    International Nuclear Information System (INIS)

    Gil Castillo, R.; Peralta Vital, J.L.; Carrazana, J.; Riverol, M.; Penn, F.; Cabrera, E.

    2004-01-01

    The present paper shows the results obtained in the framework of 2 Nuclear Projects, in the topic of application of nuclear techniques to evaluate the erosion rates in cultivated soils. Taking into account the investigations with the 137 CS technique, carried out in the Province of Pinar del Rio, was obtained and validated (first time) a methodology to evaluate the erosion impact in a cropland. The obtained methodology includes all relevant stages for the adequate application of the 137 CS technique, from the initial step of area selection, the soil sampling process, selection of the models and finally, the results evaluation step. During the methodology validation process in soils of the Municipality of San Juan y Martinez, the erosion rates estimated by the methodology and the obtained values by watershed segment measures (traditional technique) were compared in a successful manner. The methodology is a technical guide, for the adequate application of the 137 CS technique to estimate the soil redistribution rates in cultivated soils

  18. Academic Training: Toward Sustainable Energy Systems?

    CERN Multimedia

    Françoise Benz

    2006-01-01

    ACADEMIC TRAINING LECTURE SERIES 28, 29, 30, 31 March from 11:00 to 12:00 - Main Auditorium, bldg. 500 Toward Sustainable Energy Systems? F. Tellez / CIEMAT, Madrid, E and D.Martinez / CIEMAT-PSA, Almeria, E Recent work on alternative energies go in the direction of proving the feasibility of solar energy as one of the best alternatives into the future. Europe, as everybody else, has understandably vested interests in insourcing energetic demands as far as affordable. The good news is that solar energy may be its deciding straw, because it has remarkable facilities and projects probing the possibilities of this option. Two european research centers are at the leading edge in this area: ENEA, which is leading 'Archimede', a vast solar array project in Sicily, and CIEMAT, with its Plataforma Solar de Almeria (PSA, www.psa.es), a major solar energy facility at the south of Spain. Both will become basic poles of the planned 'EURO-MED'electricity interconnection, intending to carry solar electricity fro...

  19. Academic Training: Toward Sustainable Energy Systems?

    CERN Multimedia

    Françoise Benz

    2006-01-01

    ACADEMIC TRAINING LECTURE SERIES 28, 29, 30, 31 March from 11:00 to 12:00 - Main Auditorium, bldg. 500 Toward Sustainable Energy Systems? F. Tellez / CIEMAT, Madrid, E and D.Martinez / CIEMAT-PSA, Almeria, E Recent work on alternative energies go in the direction of proving the feasibility of solar energy as one of the best alternatives into the future. Europe, as everybody else, has understandably vested interests in insourcing energetic demands as far as affordable. The good news is that solar energy may be its deciding straw, because it has remarkable facilities and projects probing the possibilities of this option. Two european research centers are at the leading edge in this area: ENEA, which is leading 'Archimede', a vast solar array project in Sicily, and CIEMAT, with its Plataforma Solar de Almeria (PSA, www.psa.es) ,a major solar energy facility at the south of Spain. Both will become basic poles of the planned 'EURO-MED' electricity interconnection, intending to carry solar electricity f...

  20. Ethical Issues for Direct-to-Consumer Digital Psychotherapy Apps: Addressing Accountability, Data Protection, and Consent.

    Science.gov (United States)

    Martinez-Martin, Nicole; Kreitmair, Karola

    2018-04-23

    This paper focuses on the ethical challenges presented by direct-to-consumer (DTC) digital psychotherapy services that do not involve oversight by a professional mental health provider. DTC digital psychotherapy services can potentially assist in improving access to mental health care for the many people who would otherwise not have the resources or ability to connect with a therapist. However, the lack of adequate regulation in this area exacerbates concerns over how safety, privacy, accountability, and other ethical obligations to protect an individual in therapy are addressed within these services. In the traditional therapeutic relationship, there are ethical obligations that serve to protect the interests of the client and provide warnings. In contrast, in a DTC therapy app, there are no clear lines of accountability or associated ethical obligations to protect the user seeking mental health services. The types of DTC services that present ethical challenges include apps that use a digital platform to connect users to minimally trained nonprofessional counselors, as well as services that provide counseling steered by artificial intelligence and conversational agents. There is a need for adequate oversight of DTC nonprofessional psychotherapy services and additional empirical research to inform policy that will provide protection to the consumer. ©Nicole Martinez-Martin, Karola Kreitmair. Originally published in JMIR Mental Health (http://mental.jmir.org), 23.04.2018.

  1. Aproximación a la vida y obra del pintor y estofador alcalaíno-granadino Pedro Raxis

    Directory of Open Access Journals (Sweden)

    Gila Medina, Lázaro

    2003-12-01

    Full Text Available This article offers an approximation to the life and work of Pedro de Raxis, a key artist in Counter Reformation Granada. Raxis was the nephew of the sculptor Pablo de Rojas, who was also the master of Juan Martinez Montañés. All three were from Alcalá de Henares and pioneers in the stylistic transition from the Roman Renaissance to early Baroque naturalism. Raxis also established an extremely active studio, precursor in the formation of famous artists, and during his lifetime was considered to be the "father" of the estofa technique (the sizing, gilding and painting of wooden statuary, although his facet as a painter was underestimated.

    En el presente trabajo realizamos una aproximación a la vida y la obra de un artista clave para la Granada de la Contrarreforma: Pedro de Raxis, sobrino carnal del escultor Pablo de Rojas -maestro a su vez del también alcalaíno Juan Martínez Montañés-, todos ellos figuras pioneras al enmarcar el paso del renacimiento romanista al primer naturalismo barroco. Creador, igualmente, de un activísimo taller, precursor en la formación de renombrados artistas, fue considerado en su época como el "padre de la estofa", aunque se infravaloró su faceta de pintor.

  2. Hearing Mouth Shapes: Sound Symbolism and the Reverse McGurk Effect

    Directory of Open Access Journals (Sweden)

    Charles Spence

    2012-09-01

    Full Text Available In their recent article, Sweeny, Guzman-Martinez, Ortega, Grabowecky, and Suzuki (2012 demonstrate that heard speech sounds modulate the perceived shape of briefly presented visual stimuli. Ovals, whose aspect ratio (relating width to height varied on a trial-by-trial basis, were rated as looking wider when a /woo/ sound was presented, and as taller when a /wee/ sound was presented instead. On the one hand, these findings add to a growing body of evidence demonstrating that audiovisual correspondences can have perceptual (as well as decisional effects. On the other hand, they prompt a question concerning their origin. Although the currently popular view is that crossmodal correspondences are based on the internalization of the natural multisensory statistics of the environment (see Spence, 2011, these new results suggest instead that certain correspondences may actually be based on the sensorimotor responses associated with human vocalizations. As such, the findings of Sweeny et al. help to breathe new life into Sapir's (1929 once-popular “embodied” explanation of sound symbolism. Furthermore, they pose a challenge for those psychologists wanting to determine which among a number of plausible accounts best explains the available data on crossmodal correspondences.

  3. Teaching Commitment in the Professional Training from the Vision of the Bolivarian Primary Education

    Directory of Open Access Journals (Sweden)

    María Elena Rojas Bravo

    2017-05-01

    Full Text Available The general purpose of this article was to generate a theoretical approach on the Teachers' Commitment in the professional training process from the vision of Bolivarian primary education, in the U.E.N. Virgin of Mount Carmel. It was framed in a qualitative methodology, with an ethnographic approach. It was done based on analysis and description, based on specific situations, events, customs and observable attitudes. In order to gather information, observation and in-depth interviews were used, with dialogical interaction between investigator and informants. It was analyzed in the form of concepts and proportions taking the criteria of Martinez Migueles: categorization, structuring, contrasting and theorizing. Validity and reliability were obtained when contrasted with other investigations. The results demonstrated the need for permanent training that emphasizes innovations and the use of technologies as didactic and self-learning tools, to overcome the limitations found in pedagogical processes; Signaling a pedagogy centered on the teacher's commitment to their training. Finally, a theoretical approach was developed with the purpose of sensitizing the teacher about his commitment in the process of professional training. This intention will allow the development of methods of systematization of knowledge to be considered in the professional training of teachers.

  4. Data from mass spectrometry, NMR spectra, GC–MS of fatty acid esters produced by Lasiodiplodia theobromae

    Directory of Open Access Journals (Sweden)

    Carla C. Uranga

    2016-09-01

    Full Text Available The data described herein is related to the article with the title “Fatty acid esters produced by Lasiodiplodia theobromae function as growth regulators in tobacco seedlings” C.C. Uranga, J. Beld, A. Mrse, I. Cordova-Guerrero, M.D. Burkart, R. Hernandez-Martinez (2016 [1]. Data includes nuclear magnetic resonance spectroscopy and GC–MS data used for the identification and characterization of fatty acid esters produced by L. theobromae. GC–MS traces are also shown for incubations in defined substrate, consisting in Vogel׳s salts supplemented with either 5% grapeseed oil or 5% glucose, the two combined, or 5% fructose. Traces for incubations in the combination of 5% grapeseed oil and 5% glucose for different fungal species are also included. Images of mycelium morphology when grown in 5% glucose with or without 5% grapeseed oil are shown due to the stark difference in mycelial pigmentation in the presence of triglycerides. High concentration gradient data for the plant model Nicotiana tabacum germinated in ethyl stearate (SAEE and ethyl linoleate (LAEE is included to show the transition between growth inhibition and growth induction in N. tabacum by these compounds. Keywords: NMR, GC–MS, Fatty acid esters, Ethyl stearate, Ethyl linoleate, Growth inhibition, Growth induction

  5. Ecological studies in the NRDA process: Some guidelines for what is necessary and what is not

    International Nuclear Information System (INIS)

    Rebilliard, G.A.

    1993-01-01

    Biological resources are usually the primary focus of a natural resource damage assessment (NRDA). The NRDA should emphasize ecological studies on resources that sustained substantial injuries resulting in significant reduction of services and loss of use, and thus in substantial damages. Further, assessment costs should be ''reasonable.'' Congress, in passing the laws providing for NRDAs, did not intend that every conceivable injury to every biological resource be documented; this is economically and scientifically unreasonable. Congress did however intend that the NRDA process should be objective, based on sound science, and focused on restoration of the injured resources and services. Appropriate ecological studies should focus on the dominant sensitive habitats, major recreational species, threatened, endangered and otherwise ''sensitive'' species, and ecologically ''key'' species. However, many NRDAs have been and are being conducted in an adversarial atmosphere where the threat of litigation, not cooperation, prevails. This results in additional studies of insignificant, extremely speculative, and/or highly improbable injuries that objective, experienced ecologists would agree will not have ecological significance and should not result in damages. These studies waste time and money for all parties involved. They erode the credibility of the scientists involved as well as the credibility of the whole NRDA process. Examples of both necessary and unnecessary studies will be drawn from several oil spills including Exxon Valdez, Exxon Bayway Pipeline Leak, and Shell Martinez Manufacturing complex

  6. O CARÁTER COMPLEXO DO PROCESSO CRIATIVO EM PROJETOS INOVADORES

    Directory of Open Access Journals (Sweden)

    Maria de Fátima Bruno-Faria

    2007-08-01

    Full Text Available O objetivo do presente estudo é analisar o processo criativo em projetos inovadores ocorridos em três organizações brasileiras de natureza distinta. Pretendeu-se evidenciar a maneira complexa e dinâmica como os aspectos individuais; do grupo; da organização e extra-organizacionais se inter-relacionam no processo criativo, a partir de uma visão sistêmica que inclui categorias da teoria da subjetividade proposta por González Rey (1996, 1997, 1998, 1999, 2003, elementos da teoria da complexidade (MORIN, 1990, 1999, 2001 e a noção de criatividade como configuração defendida por Mitjáns Martinez (1997, 2000, 2004. Diferentes técnicas qualitativas e quantitativas foram utilizadas em uma concepção epistemológica qualitativa. Constatou-se que a ação dos diferentes aspectos (individuais; grupais, organizacionais e extra-organizacionais ocorre a partir de uma inter-relação complexa, singular a cada caso. Tais conclusões trazem implicações na definição de estratégias organizacionais destinadas a facilitar a expressão de idéias criativas que possibilitam inovações.

  7. Social - Ethical Commitment of Teaching Personnel from the Paradigm of Complexity

    Directory of Open Access Journals (Sweden)

    Marilú del Valle Parra Rojas

    2016-11-01

    Full Text Available The aim of this study is ethically social compromise and teachers from the perspective of complexity in educational institutions. In principle, the researchers turn to the literature review framed in socio-critical theories that permeate teaching action from its social commitment with authors like Garcia and Martinez; also cites Rodrigo Morin and from an ethical perspective. Then perform the recognition of the scenario that allows them to contextual and geographical description where the "Hero Nigale" National Basic School, likewise made the approach to the context in which the investigation was carried out and subsequently socio-political aspects of the municipality Valmore Rodriguez described; then selected in the research process community is involved, which allows collecting information through conversations and interviews with key informants; thus generating awareness spaces for reflection and discussion with stakeholders. the qualitative paradigm is inserted under the participatory action research method IAP according Latorre (2010, applying the interview technique for teachers who work in the institution. The results of this research reveal in educational interest to overcome the weaknesses in the educational process, likewise strengthen oriented social transformation practices, which involves being responsible, equitable, fair, focused on building citizens capable of being, apprehend, live and coexist with others in the same society.

  8. Ocorrência de flebotomíneos (Diptera: Psychodidae em matas de galeria no Distrito Federal, Brasil

    Directory of Open Access Journals (Sweden)

    Jônatas Ferreira

    2014-12-01

    Abstract. We analyzed the occurrence of phlebotomine sand flies in the gallery forests of the Federal District (FD, in different seasons, forest strata and conservation status. The samples were collected in three areas in the Água Limpa Farm, University of Brasília. In each area the occurrence data were analyzed in 20 collection sites visited on two months, November 2012 (rainy season and May 2013 (dry season. HP light traps were installed at 1.5 m and 10 m above the ground operating from 17:00 to 7:00 h, during three consecutive days. We set 359 trap-nights during the rainy season and 291 during the dry season. None sand fly was caught during the rainy season. In the dry season 250 sand flies were captured. The identified species were Psathyromyia runoides (Fairchild & Hertig (79.9%, Pintomyia monticola (Costa Lima (9.7%, Micropygomyia quinquefer (Dyar (3.7%, Psathyromyia shannoni (Dyar (3%, Bichromomyia flaviscutellata (Mangabeira (0.7%, Brumptomyia sp. (0.7%, Pintomyia kuscheli (Le Pont, Martinez, Torrez-Espejo & Dujardin (0.7%, Psathyromyia lutziana (Costa Lima (0.7%, and Sciopemyia sordellii (Shannon & Del Ponte (0.7%. The results indicated that in the gallery forests of the FD there is a higher occurrence of sand flies in the dry season, at ground level and in preserved areas. Pa runoides, Pi. kuscheli and Mi. quinquefer were recorded for the first time in the FD.

  9. Cross sections of the O++H2→OH++H ion-molecule reaction and isotopic variants (D2, HD): Quasiclassical trajectory study and comparison with experiments

    International Nuclear Information System (INIS)

    Martinez, Rodrigo; Sierra, Jose Daniel; Gonzalez, Miguel

    2005-01-01

    A dynamics study [cross section and microscopic mechanism versus collision energy (E T )] of the reaction O + +H 2 →OH + +H, which plays an important role in Earth's ionosphere and interstellar chemistry, was conducted using the quasiclassical trajectory method, employing an analytical potential energy surface (PES) recently derived by our group [R. Martinez et al., J. Chem. Phys. 120, 4705 (2004)]. Experimental excitation functions for the title reaction, as well as its isotopic variants with D 2 and HD, were near-quantitatively reproduced in the calculations in the very broad collision energy range explored (E T =0.01-6.0 eV). Intramolecular and intermolecular isotopic effects were also examined, yielding data in good agreement with experimental results. The reaction occurs via two microscopic mechanisms (direct and nondirect abstraction). The results were satisfactorily interpreted based on the reaction probability and the maximum impact parameter dependences with E T , and considering the influence of the collinear [OHH] + absolute minimum of the PES on the evolution from reactants to products. The agreement between theory and experiment suggests that the reaction mainly occurs through the lowest energy PES and nonadiabatic processes are not very important in the wide collision energy range analyzed. Hence, the PES used to describe this reaction is suitable for both kinetics and dynamics studies

  10. 29 September 2015 - Vice-President of the Government of Spain S. Sáenz de Santamaría in the ATLAS visitor centre, the Synchrocyclotron, the Data Centre visit point and the LHC magnet facility with CERN Director-General R. Heuer and Technology Department Head J.M. Jiménez.

    CERN Multimedia

    Bennett, Sophia Elizabeth

    2015-01-01

    Were also present from Spain: Sra. Carmen Vela, Secretaria de Estado de Investigación, Desarrollo e Innovación, Sr. D. Bernardo de Sicart Escoda Embajador de España en Berna, Sra. Da Ana Menéndez Pérez, Embajadora Representante Permanente de España ante Naciones Unidas y OOII con sede en Ginebra, Sra. Da María Pico Directora del Gabinete de la Vicepresidenta and Sr. D. Miguel Temboury Redondo Subsecretario de Economía y Competitividad. And from CERN: Dr Maria Alandes Pradillo, Information Technology Department, Dr Maria Barroso-Lopez Deputy Group Leader, IT-PES, Dr Frédérick Bordry, Director of Accelerators and Technology, Dr Borja Fernandez Adiego Engineering Department, Prof. Maria Jose Garcia Borge ISOLDE Collaboration Spokesperson, Dr Fabiola Gianotti Director-General elect 2016-2020, Mr Frédéric Hemmer Information Technology Department Head, Prof. Mario Martinez, Spanish Scientific Delegate to CERN Council Mr Guillermo Merino Fernandez, Technology Department Mr Lluis Miralles, General Infrast...

  11. La dirección de SOMISA durante la última dictadura militar, 1976-1983. Del restablecimiento de la disciplina en el trabajo al fundamento de la república democrática

    Directory of Open Access Journals (Sweden)

    ANDRÉS CARMINATI

    2013-05-01

    Full Text Available El presente trabajo es un estudio de las actitudes y posiciones políticas de la dirección de la empresa Sociedad Mixta Siderurgia Argentina (SOMISA durante la última Dictadura Militar (1976-1983. Procura analizar el rol de la dirección de la empresa, que dependía de la Dirección General de Fabricaciones Militares, en el contexto signado por las políticas económicas del plan Martínez de Hoz, que preveían reducir la participación del Estado en la economía. Abstract This paper studies de attitudes and political positions of the SOMISA’s (Mix Society Argentine´s Iron and Steel Industry management during the last Military Dictator Sheep (1976-1983. Procures to analyze the factory´s management´s role in a context signed for the economical politics of Martinez de Hoz´s plans, designed to reduce the State´s participation in the economy, while SOMISA depends of the General Direction of Military Industries.

  12. Asthma referrals: a key component of asthma management that needs to be addressed

    Directory of Open Access Journals (Sweden)

    Price D

    2017-07-01

    Full Text Available David Price,1,2 Leif Bjermer,3 David A Bergin,4 Rafael Martinez5 1Centre of Academic Primary Care, University of Aberdeen, Aberdeen, UK; 2Observational and Pragmatic Research Institute, Singapore; 3Department of Respiratory Medicine and Allergology, Lund University, Lund, Sweden; 4Novartis Ireland Limited, Dublin, Ireland; 5Novartis Pharma AG, Basel, Switzerland Abstract: Heterogeneity of asthma and difficulty in achieving optimal control are the major challenges in the management of asthma. To help attain the best possible clinical outcomes in patients with asthma, several guidelines provide recommendations for patients who will require a referral to a specialist. Such referrals can help in clearing the uncertainty from the initial diagnosis, provide tailored treatment options to patients with persistent symptoms and offer the patients access to health care providers with expertise in the management of the asthma; thus, specialist referrals have a substantial impact on disease prognosis and the patient’s health status. Hurdles in implementing these recommendations include lack of their dissemination among health care providers and nonadherence to these guidelines; these hurdles considerably limit the implementation of specialist referrals, eventually affecting the rate of referrals. In this review, recommendations for specialist referrals from several key international and national asthma guidelines and other relevant published literature are evaluated. Furthermore, we highlight why referrals are not happening, how this can be improved, and ultimately, what should be done in the specialist setting, based on existing evidence in published literature. Keywords: asthma, disease management, specialization, primary care physicians, referral

  13. Identification of a system of ecologically homogeneous areas and of priority intervention levels for forest plantation planning in Sicily

    Directory of Open Access Journals (Sweden)

    Pizzurro GM

    2008-10-01

    Full Text Available Afforestation and reforestation activities in Sicily have been widespreaded in the last century. The results of forestation activities indicate the need to adopt a operational tools to promote the extension of forest surface at regional and sub-regional levels. In this view, with the aim to produce useful tools for forest plantation planning, the entire regional area was analysed and ecologically homogeneous areas have been identified to join and target arboriculture and/or forestation plantation activities, to choose tree and shrub species for different environments and to identify priority areas of intervention. The map of Rivas-Martinez bioclimate and the map of litological types were used as basic information layers to map pedo-climatic homogeneous areas. In order to mitigate disruptive hydrogeological effects and to reduce desertification risk and forest fragmentation, the Corine Land Cover map (CLC2000, the hydrogeological bond map and the desertification risk map were used to identify areas characterized by urgent need of forest activities at high priority level. A total of 23 ecologically homogeneous areas have been identified in Sicily, while more than a quarter of the regional surface has been characterized as highest priority intervention level. At sub-regional level, the target of the analysis was carried out at administrative province and at hydrographic basin level.

  14. EURISOL-DS multi-MW target unit: Neutronics performance and shielding assessment, dose rate and material activation calculations for the MAFF configuration

    CERN Document Server

    Romanets, Y; Kadi, Y; Luis, R; Goncalves, I F; Tecchio, L; Kharoua, C; Vaz, P; Ene, D; David, J C; Rocca, R; Negoita, F

    2010-01-01

    One of the objectives of the EURISOL (EURopean Isotope Separation On-Line Radioactive Ion Beam) Design Study consisted of providing a safe and reliable facility layout and design for the following operational parameters and characteristics: (a) a 4 MW proton beam of 1 GeV energy impinging on a mercury target (the converter); (b) high neutron fluxes (similar to 3 x 10(16) neutrons/s) generated by spallation reactions of the protons impinging in the converter and (c) fission rate on fissile U-235 targets in excess of 10(15) fissions/s. In this work, the state-of-the-art Monte Carlo codes MCNPX (Pelowitz, 2005) and FLUKA (Vlachoudis, 2009; Ferrari et al., 2008) were used to characterize the neutronics performance and to perform the shielding assessment (Herrera-Martinez and Kadi, 2006; Cornell, 2003) of the EURISOLTarget Unit and to provide estimations of dose rate and activation of different components, in view of the radiation safety assessment of the facility. Dosimetry and activation calculations were perfor...

  15. What is this chocolate milk in my circuit? A cause of acute clotting of a continuous renal replacement circuit: Questions.

    Science.gov (United States)

    Kakajiwala, Aadil; Chiotos, Kathleen; Brothers, Julie; Lederman, April; Amaral, Sandra

    2016-12-01

    One of the greatest problems associated with continuous renal replacement therapy (CRRT) is the early clotting of filters. A literature search revealed three case reports of lipemic blood causing recurrent clotting and reduced CRRT circuit survival time in adult patients, but no reports of cases in children. A 23-month-old male infant with Martinez-Frias syndrome and multivisceral transplant was admitted to the hospital with severe sepsis and hemolytic anemia. He developed acute kidney injury, fluid overload and electrolyte imbalances requiring CRRT and was also administered total parenteral nutrition (TPN) and fat emulsion. The first circuit lasted 60 h before routine change was required. The second circuit showed acute clotting after only 18 h, and brownish-milky fluid was found in the circuit tubing layered between the clotted blood. The patient's serum triglyceride levels were elevated at 988 mg/dL. The lipid infusion was stopped and CRRT restarted. Serum triglyceride levels improved to 363 mg/dL. The new circuit lasted 63 h before routine change was required. Clotting of CRRT circuits due to elevated triglyceride levels is rare and has not been reported in the pediatric population. Physicians should be mindful of this risk in patients receiving TPN who have unexpected clotting of CRRT circuits.

  16. The arches of the Sanctuary of Loyola. The relationship between the Roman project and Spanish building techniques

    Directory of Open Access Journals (Sweden)

    Iacopo Benincampi

    2015-12-01

    Full Text Available The ascent to the throne of Spain in 1714 by Philip V of Bourbon ended the War of the Spanish Succession, and opened a new period of peace and prosperity that is reflected mainly in the building sites sponsored by the Crown, including also the factory of the Sanctuary of Loyola, which restarted the construction under the leadership of Sebastian Lecuna, who was in charge of raising the circular church. However, the complexity of the project, edited by Carlo Fontana and sent from Rome in 1686, and the changes already made in the plant imposed a careful preliminary reflection which resulted in 1719 in a consultation which was attended by the former director of the factory, Martin de Zaldua, the theoretical Benedictine Pedro Martinez de Cardeña and the Salamanca Cathedral master mayor Joaquin de Churriguera. The masters were contacted to express their opinion about the construction of the vaults of the nave ring, the decoration and especially on the most suitable form to be assigned to the arches of the church, a subject of great interest cause of their uniqueness and complexity. In this sense, the loss of the original drawings do not allow a proper understanding neither of the proposals submitted or the final solution adopted but, nevertheless, a careful study of archival records and the reconstruction of the stereotomic geometry underlies these arches now has led to new contributions, which are useful to a greater general understanding of the factory. Keywords: Loyola, Stereotomy, Carlo Fontana, Sebastian Lecuna, arches

  17. Tribal Odisha Eye Disease Study (TOES # 2 Rayagada school screening program: efficacy of multistage screening of school teachers in detection of impaired vision and other ocular anomalies

    Directory of Open Access Journals (Sweden)

    Panda L

    2018-06-01

    Full Text Available Lapam Panda,1 Taraprasad Das,1 Suryasmita Nayak,1 Umasankar Barik,2 Bikash C Mohanta,1 Jachin Williams,3 Vivekanand Warkad,4 Guha Poonam Tapas Kumar,5 Rohit C Khanna3 1Indian Oil Center for Rural Eye Health, GPR ICARE, L V Prasad Eye Institute, MTC Campus, Bhubaneswar, India; 2Naraindas Morbai Budhrani Eye Centre, L V Prasad Eye Institute, Rayagada, India; 3Gullapalli Pratibha Rao International Center for Advancement of Rural Eye Care, L V Prasad Eye Institute, KAR Campus, Hyderabad, India; 4Miriam Hyman Children Eye Care Center, L V Prasad Eye Institute, MTC Campus, Bhubaneswar, India; 5District Administration, Government of Odisha, Rayagada, India Purpose: To describe program planning and effectiveness of multistage school eye screening and assess accuracy of teachers in vision screening and detection of other ocular anomalies in Rayagada District School Sight Program, Odisha, India.Methods: This multistage screening of students included as follows: stage I: screening for vision and other ocular anomalies by school teachers in the school; stage II: photorefraction, subjective correction and other ocular anomaly confirmation by optometrists in the school; stage III: comprehensive ophthalmologist examination in secondary eye center; and stage IV: pediatric ophthalmologist examination in tertiary eye center. Sensitivity, specificity, positive predictive value (PPV and negative predictive value (NPV of teachers for vision screening and other ocular anomaly detection were calculated vis-à-vis optometrist (gold standard.Results: In the study, 216 teachers examined 153,107 (95.7% of enrolled students aged 5–15 years. Teachers referred 8,363 (5.4% of examined students and 5,990 (71.6% of referred were examined in stage II. After prescribing spectacles to 443, optometrists referred 883 students to stage III. The sensitivity (80.51% and PPV (93.05% of teachers for vision screening were high, but specificity (53.29% and NPV (26.02% were low. The

  18. Reviews of recent publications

    Directory of Open Access Journals (Sweden)

    1997-06-01

    Full Text Available Culture and Theory Conley, Verena Andermatt, ed. Rethinking Technologies by Laurence M. Porter Leitch, Vincent B. Cultural Criticism, Literary Theory, Poststructuralism by Merry M. Pawlowski French Studies Bersani, Leo and Ulysse Dutoit. Arts of Impoverishment: Beckett, Rothko, Resnais by Thomas Trezise Boldt-Irons, Leslie Anne. On Bataille: Critical Essays by Walter A. Strauss Deleuze, Gilles. Negotiations . Trans. Martin Joughin by Charles J. Stivale Fisher, Dominique D. Staging of Language and Language(s of the Stage: Mallarmé's poëme critique and Artaud's poetry-minus-text by Maryse Fauvel Goodall, Jane. Artaud and the Gnostic Drama by Claudine G. Fisher Lydon, Mary. Skirting the Issue: Essays in Literary Theory by Carol J. Murphy German Studies Barnouw, Dagmar. Critical Realism: History, Photography, and the Work of Siegfried Kracauer by Florence Martin Pfandl-Buchegger, Ingrid. David Lodge als Literaturkritiker, Theoretiker and Romanautor by Charles A. Grair Samuels, Clarise. Holocaust Visions: Surrealism and Existentialism in the Poetry of Paul Celan by Francis Michael Sharp Stefan, Verena. Shedding and Literally Dreaming. Shedding. Trans. Johanna Steigleder Moore and Beth E. Weckmueller; Literally Dreaming . Trans. Johanna Albert and Tobe Levin; "Euphoria and Cacophony." Trans. and Afterword Tobe Levin by Miriam Frank Stern, J.P. The Dear Purchase: A Theme in German Modernism by Theodore Ziolkowski Russian Studies Berry, Ellen E. and Anesa Miller-Pogacer, eds. Re-Entering the Sign: Articulating New Russian Culture by Rolf Hellebust Erlich, Victor. Modernism and Revolution: Russian Literature in Transition by Henry Elbaum Hohne, Karen and Helen Wussow, eds. A Dialogue of Voices: Feminist Literary Theory and Bakhtin by Laura Beraha Masing-Delic, Irene. Abolishing Death: A Salvation Myth of Russian Twentieth-Century Literature by Rolf Hellebust Paperno, Irina and Joan Delaney Grossman, eds. Creating Life: The Aesthetic Utopia of Russian

  19. Proceedings of the 19th ASPA Congress, Cremona, June 7-10, 2011

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    Guest Editor: Giacomo Pirlo

    2011-06-01

    Full Text Available The 19th Congress of the Animal Science and Production Association (ASPA, is held in the capital of one of the main European regions for animal production: Cremona. Despite its Gallic origin (Carra = rock, the name Cremona means big cream in modern Italian, in a clear allusion to milk. In this Congress, 153 oral presentations and 165 posters are presented, for a total of 318 scientific contributions. The Congress sessions with their relative number of papers are listed as follows: Animal breeding and genetics 87, Nutrition and feeding 57, Dairy production 40, Meat production 46, Animal welfare, Health and behaviour 37, Poultry and rabbit production 28 and Aquaculture 23. I would like to point out that 4 main lectures will be presented in the Animal breeding and genetics and Nutrition and feeding sessions (two in each, and that the Consiglio per la Ricerca in Agricoltura (Agricultural Research Council, the Agricultural Ministery research agency, which took charge of organizing the Congress, will award a prize for the best work here presented by young researchers. I would thank, first of all, Prof. Paolo Cescon, President of the Congress, for the contribution of all the CRA in organizing this event. I would also thank all the members of the Scientific Committee, dr. Riccardo Aleandri (President, dr. Fabio Abeni, dr. Fabiola Canavesi, dr. Giacinto Della Casa and dr. Marisanna Speroni, and of the Organizing Committee, dr. Giovanni Lo Piparo (President, dr. Stefania Barzaghi, dr. Maurizio Capelletti, dr. Giorgio Giraffa and dr. Luciano Migliorati. A special thanks to the secretary components, Maria Dissegna and Patrizia Re, assisted by Claudia Federici, Francesca Petrera, Miriam Odoardi, Maddalena Carli, Caterina Sanna, Stefania Marruso, Leonardo Boselli, Milena Rosi and Aldo Dal Prà. A special acknowlegment to Giacomo Pirlo, the real driving force organizing the Congress, a tireless and enthusiastic embroiderer of opportunities in scientific and

  20. Conjugation of quantum dots on carbon nanotubes for medical diagnosis and treatment

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    Madani SY

    2013-03-01

    Full Text Available Seyed Yazdan Madani,1 Farzad Shabani,3 Miriam V Dwek,2 Alexander M Seifalian1,3 1UCL Centre for Nanotechnology and Regenerative Medicine, University College, London, UK; 2Department of Molecular and Applied Biosciences, School of Life Sciences, University of Westminster, London, UK; 3Royal Free London NHS Foundation Trust Hospital, London, UK Abstract: Cancer is one of the leading causes of death worldwide and early detection provides the best possible prognosis for cancer patients. Nanotechnology is the branch of engineering that deals with the manipulation of individual atoms and molecules. This area of science has the potential to help identify cancerous cells and to destroy them by various methods such as drug delivery or thermal treatment of cancer. Carbon nanotubes (CNT and quantum dots (QDs are the two nanoparticles, which have received considerable interest in view of their application for diagnosis and treatment of cancer. Fluorescent nanoparticles known as QDs are gaining momentum as imaging molecules with life science and clinical applications. Clinically they can be used for localization of cancer cells due to their nano size and ability to penetrate individual cancer cells and high-resolution imaging derived from their narrow emission bands compared with organic dyes. CNTs are of interest to the medical community due to their unique properties such as the ability to deliver drugs to a site of action or convert optical energy into thermal energy. By attaching antibodies that bind specifically to tumor cells, CNTs can navigate to malignant tumors. Once at the tumor site, the CNTs enter into the cancer cells by penetration or endocytosis, allowing drug release, and resulting in specific cancer cell death. Alternatively, CNTs can be exposed to near-infrared light in order to thermally destroy the cancer cells. The amphiphilic nature of CNTs allows them to penetrate the cell membrane and their large surface area (in the order of 2600 m2

  1. Preferences of patients undergoing hemodialysis – results from a questionnaire-based study with 4,518 patients

    Directory of Open Access Journals (Sweden)

    Janssen IM

    2015-06-01

    Full Text Available Inger Miriam Janssen,1 Ansgar Gerhardus,2,3 Gero D von Gersdorff,4 Conrad August Baldamus,4 Mathias Schaller,4 Claudia Barth,5 Fueloep Scheibler6 1Department of Epidemiology and International Public Health, Bielefeld University, Bielefeld, Germany; 2Department for Health Services Research, University of Bremen, Bremen, Germany; 3Health Sciences Bremen, University of Bremen, Bremen, Germany; 4Department of Internal Medicine II, University Hospital of Cologne, Cologne, Germany; 5KfH Kuratorium fuer Dialyse und Nierentransplantation e.V., Neu-Isenburg, Germany; 6Department of Non-Drug Interventions, Institute for Quality and Efficiency in Health Care, Cologne, Germany Background: Chronic kidney disease is an increasing health problem worldwide and in its final stage (stage V can only be treated by renal replacement therapy, mostly hemodialysis. Hemodialysis has a major influence on the everyday life of patients and many patients report dissatisfaction with treatment. Little is known about which aspects of treatment are considered important by hemodialysis patients. The objective of this study was to rate the relative importance of different outcomes for hemodialysis patients and to analyze whether the relative importance differed among subgroups of patients.Patients and methods: Within the framework of a yearly questionnaire which is distributed among patients receiving hemodialysis by the largest hemodialysis provider in Germany, we assessed the relative importance of 23 outcomes as rated on a discrete visual analog scale. Descriptive statistics were used to rank the outcomes. Subgroup analyses were performed using Mann–Whitney U or Kruskal–Wallis tests.Results: Questionnaires of 4,518 hemodialysis patients were included in the analysis. The three most important outcomes were safety of treatment, health-related quality of life, and satisfaction with care. Further important outcomes were hospital stays, accompanying symptoms, hemodialysis

  2. Long-term evolution of lung function in individuals with alpha-1 antitrypsin deficiency from the Spanish registry (REDAAT

    Directory of Open Access Journals (Sweden)

    Esquinas C

    2018-03-01

    Full Text Available Cristina Esquinas,1,2,* Sonia Serreri,3,* Miriam Barrecheguren,1 Esther Rodriguez,1 Alexa Nuñez,1 Francisco Casas-Maldonado,4 Ignacio Blanco,5 Pietro Pirina,3 Beatriz Lara,6 Marc Miravitlles1,7 1Pneumology Department, University Hospital Vall d’Hebron, Barcelona, Spain; 2Public Health, Mental, Maternal and Child Health Nursing Department, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain; 3Università di Sassari, Sassari, Italy; 4Pneumology Department, University Hospital San Cecilio, Granada, Spain; 5Alpha-1 Antitrypsin Deficiency Spanish Registry (REDAAT, Spanish Society of Pneumology (SEPAR, Barcelona, Spain; 6Coventry and Warwickshire University Hospital, Coventry, UK; 7CIBER de Enfermedades Respiratorias (CIBERES, Spain *These authors contributed equally to this work Background: The clinical course of alpha-1 antitrypsin deficiency (AATD is very heterogeneous. It is estimated that 60% of individuals with severe AATD (Pi*ZZ develop emphysema. The main objective of this study was to describe the outcomes of long-term lung function in individuals with AATD-associated emphysema after at least 8 years of follow-up. Materials and methods: We performed a retrospective analysis of longitudinal follow-up data of AATD PiZZ patients from the Spanish registry (AATD Spanish Registry [REDAAT]. The main follow-up outcome was the annual rate of decline in forced expiratory volume in 1 second (FEV1 calculated using the FEV1 values at baseline and in the last post-bronchodilator spirometry available. Results: One hundred and twenty-two AATD PiZZ patients were analyzed. The median follow-up was 11 years (interquartile range =9–14. The mean FEV1 decline was 28 mL/year (SD=54, with a median of 33 mL/year. Tobacco consumption (β=19.8, p<0.001, previous pneumonia (β=27.8, p=0.026 and higher baseline FEV1% (β=0.798, p=0.016 were independently related to a faster FEV1 decline. Conclusion: In this large cohort with a long

  3. Induction of long noncoding RNA MALAT1 in hypoxic mice

    Directory of Open Access Journals (Sweden)

    Lelli A

    2015-10-01

    Full Text Available Aurelia Lelli,1,2,* Karen A Nolan,1,2,* Sara Santambrogio,1,2 Ana Filipa Gonçalves,1,2 Miriam J Schönenberger,1,2 Anna Guinot,1,2 Ian J Frew,1,2 Hugo H Marti,3 David Hoogewijs,1,2,4 Roland H Wenger1,2 1Institute of Physiology and Zurich Center for Human Physiology (ZIHP, University of Zurich, Zurich, Switzerland; 2National Center of Competence in Research "Kidney.CH", Zurich, Switzerland; 3Institute of Physiology and Pathophysiology, University of Heidelberg, Heidelberg, Germany; 4Institute of Physiology, University of Duisburg-Essen, Essen, Germany *These authors contributed equally to this work Abstract: Long thought to be “junk DNA”, in recent years it has become clear that a substantial fraction of intergenic genomic DNA is actually transcribed, forming long noncoding RNA (lncRNA. Like mRNA, lncRNA can also be spliced, capped, and polyadenylated, affecting a multitude of biological processes. While the molecular mechanisms underlying the function of lncRNAs have just begun to be elucidated, the conditional regulation of lncRNAs remains largely unexplored. In genome-wide studies our group and others recently found hypoxic transcriptional induction of a subset of lncRNAs, whereof nuclear-enriched abundant/autosomal transcript 1 (NEAT1 and metastasis-associated lung adenocarcinoma transcript 1 (MALAT1 appear to be the lncRNAs most ubiquitously and most strongly induced by hypoxia in cultured cells. Hypoxia-inducible factor (HIF-2 rather than HIF-1 seems to be the preferred transcriptional activator of these lncRNAs. For the first time, we also found strong induction primarily of MALAT1 in organs of mice exposed to inspiratory hypoxia. Most abundant hypoxic levels of MALAT1 lncRNA were found in kidney and testis. In situ hybridization revealed that the hypoxic induction in the kidney was confined to proximal rather than distal tubular epithelial cells. Direct oxygen-dependent regulation of MALAT1 lncRNA was confirmed using isolated primary

  4. Parkinson’s disease patients’ subjective descriptions of characteristics of chronic pain, sleeping patterns and health-related quality of life

    Directory of Open Access Journals (Sweden)

    Skogar Ö

    2012-10-01

    Full Text Available Örjan Skogar,1,5 Per-Arne Fall,2 Gunnar Hallgren,3 Birgitta Bringer,2 Miriam Carlsson,1 Ulla Lennartsson,3 Håkan Sandbjörk,3 Carl-Johan Törnhage,4 Johan Lökk51Department of Geriatrics, Ryhov Hospital, Jonkoping, Sweden; 2Department of Geriatrics, University Hospital, Linkoping, Sweden; 3Department of Neurology, 4Department of Pediatrics, Skaraborg Hospital, Skövde, Sweden; 5Institution of Neurobiology, Karolinska Institutet, Stockholm, SwedenObjective: Nonmotor symptoms are common in Parkinson’s disease (PD. Health-related quality of life (HRQoL is negatively affected by different factors, of which pain and sleep disturbances are important contributors. This study was performed to evaluate and describe subjective experiences of pain, sleeping patterns, and HRQoL in a cohort of PD patients with chronic pain.Methods: A total of 45 participants with established PD for more than 2 years, and PD-related pain for the preceding three months, were recruited from three sites in Sweden. Data regarding time point for onset, duration and degree of pain parameters, body localization of pain, external influences, and treatments were obtained. HRQoL was evaluated with the Short Form-36® Health Survey, and sleeping patterns were registered with the Parkinson’s disease Sleep Scale, both completed along with a questionnaire.Results: In one-third of participants, pain preceded the PD diagnosis. Median pain score measured with a visual analog scale was 6.6 and 5.9 (for females and males, respectively the week before the study. In almost half of the participants, pain was present during all their waking hours. Significantly more females described their pain as troublesome, while more males described their pain as irritating. Feelings of numbness and creeping sensations at night were strongly associated with the maximal visual analog scale scores. Polypharmacy was common; 89% used medication for anxiety/insomnia, and 18% used antidepressants. Only one

  5. Pain management in patients with dementia

    Directory of Open Access Journals (Sweden)

    Achterberg WP

    2013-11-01

    Full Text Available Wilco P Achterberg,1 Marjoleine JC Pieper,2 Annelore H van Dalen-Kok,1 Margot WM de Waal,1 Bettina S Husebo,3 Stefan Lautenbacher,4 Miriam Kunz,4 Erik JA Scherder,5 Anne Corbett6 1Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, 2Department of General Practice and Elderly Care Medicine, VU University Medical Center Amsterdam, Amsterdam, The Netherlands; 3Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway; 4Physiological Psychology, Otto Friedrich University Bamberg, Bamberg, Germany; 5Department of Clinical Neuropsychology, VU University Amsterdam, Amsterdam, The Netherlands; 6Wolfson Centre for Age-Related Diseases, King's College London, London, UK Abstract: There are an estimated 35 million people with dementia across the world, of whom 50% experience regular pain. Despite this, current assessment and treatment of pain in this patient group are inadequate. In addition to the discomfort and distress caused by pain, it is frequently the underlying cause of behavioral symptoms, which can lead to inappropriate treatment with antipsychotic medications. Pain also contributes to further complications in treatment and care. This review explores four key perspectives of pain management in dementia and makes recommendations for practice and research. The first perspective discussed is the considerable uncertainty within the literature on the impact of dementia neuropathology on pain perception and processing in Alzheimer's disease and other dementias, where white matter lesions and brain atrophy appear to influence the neurobiology of pain. The second perspective considers the assessment of pain in dementia. This is challenging, particularly because of the limited capacity of self-report by these individuals, which means that assessment relies in large part on observational methods. A number of tools are available but the psychometric quality and clinical utility of these are

  6. Testosterone replacement therapy among elderly males: the Testim Registry in the US (TRiUS

    Directory of Open Access Journals (Sweden)

    Bhattacharya RK

    2012-08-01

    Full Text Available Rajib K Bhattacharya,1 Mohit Khera,2 Gary Blick,3 Harvey Kushner,4 Martin M Miner51Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA; 2Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA; 3Circle Medical LLC, Norwalk, CT, USA; 4Biometrics, Auxilium Pharmaceuticals, Malvern, PA, USA; 5Men's Health Center, Miriam Hospital, Providence, RI, USABackground: Testosterone levels naturally decline with age in men, often resulting in testosterone deficiency (hypogonadism. However, few studies have examined hypogonadal characteristics and treatment in older (≥65 years men.Objective: To compare data at baseline and after 12 months of testosterone replacement therapy (TRT in hypogonadal men ≥65 vs <65 years old. Data for participants 65–74 vs ≥75 years old were also compared.Methods: Data were from TRiUS (Testim Registry in the United States, which enrolled 849 hypogonadal men treated with Testim® 1% (50–100 mg testosterone gel/day for the first time. Anthropometric, laboratory, and clinical measures were taken at baseline and 12 months, including primary outcomes of total testosterone (TT, free testosterone (FT, and prostate-specific antigen (PSA levels. Comparisons of parameters were made using Fisher's exact test or analysis of variance. Nonparametric Spearman's ρ and first-order partial correlation coefficients adjusted for the effect of age were used to examine bivariate correlations among parameters.Results: Of the registry participants at baseline with available age information, 16% (133/845 were ≥65 years old. They were similar to men <65 years old in the duration of hypogonadism prior to enrollment (~1 year, TT and FT levels at baseline, TT and FT levels at 12-month follow-up, and in reported compliance with treatment. Older patients were more likely to receive lower doses of TRT. PSA levels did not statistically differ between groups after 12 months of TRT (2.18 ± 2.18 ng

  7. Effectiveness of Two Web-Based Interventions for Chronic Cancer-Related Fatigue Compared to an Active Control Condition: Results of the "Fitter na kanker" Randomized Controlled Trial.

    Science.gov (United States)

    Bruggeman-Everts, Fieke Z; Wolvers, Marije D J; van de Schoot, Rens; Vollenbroek-Hutten, Miriam M R; Van der Lee, Marije L

    2017-10-19

    the perceived high intensity of the program. Both the AAF and eMBCT interventions are effective for managing fatigue severity compared to receiving psycho-educational emails. Trialregister.nl NTR3483; http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=3483 (Archived by WebCite at http://www.webcitation.org/6NWZqon3o). ©Fieke Z. Bruggeman-Everts, Marije D. J. Wolvers, Rens van de Schoot, Miriam M. R. Vollenbroek-Hutten, Marije L. Van der Lee. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 19.10.2017.

  8. Negatively charged silver nanoparticles with potent antibacterial activity and reduced toxicity for pharmaceutical preparations

    Directory of Open Access Journals (Sweden)

    Salvioni L

    2017-03-01

    Full Text Available Lucia Salvioni,1 Elisabetta Galbiati,1 Veronica Collico,1 Giulia Alessio,1 Svetlana Avvakumova,1 Fabio Corsi,2,3 Paolo Tortora,1 Davide Prosperi,1 Miriam Colombo1 1Nanobiolab, Department of Biotechnology and Bioscience, University of Milano-Bicocca, 2Biological and Clinical Science Department, University of Milan, Milano, 3Surgery Department, Breast Unit, IRCCS S Maugeri Foundation, Pavia, Italy Background: The discovery of new solutions with antibacterial activity as efficient and safe alternatives to common preservatives (such as parabens and to combat emerging infections and drug-resistant bacterial pathogens is highly expected in cosmetics and pharmaceutics. Colloidal silver nanoparticles (NPs are attracting interest as novel effective antimicrobial agents for the prevention of several infectious diseases.Methods: Water-soluble, negatively charged silver nanoparticles (AgNPs were synthesized by reduction with citric and tannic acid and characterized by transmission electron microscopy, dynamic light scattering, zeta potential, differential centrifuge sedimentation, and ultraviolet–visible spectroscopy. AgNPs were tested with model Gram-negative and Gram-positive bacteria in comparison to two different kinds of commercially available AgNPs.Results: In this work, AgNPs with higher antibacterial activity compared to the commercially available colloidal silver solutions were prepared and investigated. Bacteria were plated and the antibacterial activity was tested at the same concentration of silver ions in all samples. The AgNPs did not show any significant reduction in the antibacterial activity for an acceptable time period. In addition, AgNPs were transferred to organic phase and retained their antibacterial efficacy in both aqueous and nonaqueous media and exhibited no toxicity in eukaryotic cells.Conclusion: We developed AgNPs with a 20 nm diameter and negative zeta potential with powerful antibacterial activity and low toxicity compared

  9. Editorial, n. 12, 2001

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    Editor Encontros Bibli

    2001-01-01

    Full Text Available EDITORIAL, n. 12, 2001 Este número da Encontros Bibli apresenta diferentes abordagens de questões relativas à sociedade do conhecimento. Esta sociedade vem acompanhada de uma evolução tecnológica que afeta, em diferentes graus, todos os países do mundo, produzindo impactos de natureza econômica, política, social e cultural. Tais impactos necessitam de parâmetros para sua análise e avaliação. A medição de bens intangíveis, neste caso, provenientes do uso das tecnologias da informação e da comunicação, é uma tarefa complexa. O artigo do professor Michel Menou, da City University, de Londres, apresenta uma metodologia original para análise desses indicadores na sociedade atual. O relato de pesquisa da professora Clarice Fortkamp Caldin, do Departamento de Ciência da Informação da UFSC, aborda o processo de leitura como função terapêutica. Este trabalho é baseado na sua dissertação de mestrado e representa um foco de abordagem pouco usual na Ciência da Informação. O professor Francisco das Chagas de Souza, também do Departamento de Ciência da Informação da UFSC, apresenta uma análise de sua experiência no ensino de fundamentos teóricos da Biblioteconomia. A estudante Maria Elizabeth Horn Pepulim, do Curso de Biblioteconomia da UFSC, reflete sobre o papel do bibliotecário na sociedade da informação, ressaltando os dilemas, atribuições e responsabilidades deste profissional no mundo globalizado. Esta edição divulga ainda uma pesquisa sobre bibliotecas públicas, sociedade da informação e tecnologia, que está sendo desenvolvida pelos colegas do Instituto de Investigaciones Bibliotecológicas da Universidad de Buenos Aires: Elsa Barber, Nicolás Tripaldi, Silvia Pisano, Valeria Werner, Sofia D´Alessandro, Sandra Romagnoli, Verónica Parsiale, Carolina Gregui e Gabriela De Pedro. Miriam Vieira da Cunha, editora Disponibilizado na WWW em 28/12/2001. Enc. Bibli: R. Eletr. Bibliotecon. Ci. Inf., ISSN 1518

  10. Book Reviews

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    J. Peter White

    1974-01-01

    Full Text Available - J.G. Oosten, Peter Fuchs, Kult und Autorität: de Religion der Hadjerai. Dietrich Reimer Verlag, Berlin 1970. 395 S., 12 Karten, 38 Abb., 52 Photos. - J.P. Boendermaker, Björn Björnsson, The Lutheran doctrine of marriage in modern Icelandic society. Oslo, Reykjavik 1971. 250 p. - H.C.G. Schoenmaker, J. van Baal, Symbols for communication. An introduction to the anthropological study of religion. Van Gorcum & Comp. N.V. Assen, 1971. I-XII, 295 p. - Miriam de Beet-Sterman, Jean Hurault, Africains de Guyane. La vie matérielle et l’art des Noirs Réfugiés de Guyana. Mouton, La Haye-Paris 1970. 224 pp., 47 foto’s en illustraties. - Stephen Wild, Alan Lomax, Folk song style and culture. American Association for the Advancement of Science, Washington, D.C., 1968. xix, 308 pp., 3 appendices, bibliog., illus., maps. - Aidan Southall, A.H.J. Prins, Didemic Lamu: Social stratification and spatial structure in a Muslim maritime town. Instituut voor Culturele Antropologie der Rijksuniversiteit Groningen 1971. 68 pp., 4 diag., 4 figs., Map. - H.J.M. Claessen, Irving Goldman, Ancient Polynesian society. The University of Chicago Press. Chicago and London 1970. 625 pp., bibl., appendices, register. - J. van Baal, Paula Brown, The Chimbu: A study of change in the New Guinea Highlands. Schenkman Publishing Cy, Inc., Cambridge, Massachussets 1972, 151 + IX pp. - P. van de Velde, J. Peter White, Ol Tumbana - Archaeological excavations in the Eastern Central Highlands, Papua New Guinea. Terra Australis 2. Department of Pre-History, Research School of Pacific Studies, The Australian National University, Canberra, 1972. xx + 176 pp., 170 tables, 28 figs., 5 plates. - Ajatrohaedi, Tom Harrison, Gold and megalithic activity in prehistoric and recent West Borneo. New York, Southeast Asia Program, Department of Asian Studies. Cornell University, Data Paper number 77, 1970. XIV and 331 pp., map, ills., Stanley J. O’Connor (eds. - David S. Moyer, James A. Tuck

  11. Psychological well-being among US adults with arthritis and the unmet need for mental health care

    Directory of Open Access Journals (Sweden)

    Straub LE

    2017-05-01

    Full Text Available Laura E Straub,1,2 Miriam G Cisternas3 1Emory University, Atlanta, GA, 2Immune Tolerance Network, San Francisco, CA, 3MGC Data Services, Carlsbad, CA, USA Purpose: Mental health conditions can increase the risk of disability among adults with arthritis. The objective of this analysis was to compare the prevalence of serious psychological distress (SPD, depression, and anxiety among US adults with arthritis vs. those without; characterize adults with arthritis with and without SPD; and determine correlates of seeing a mental health professional during the year for adults with arthritis and SPD.Materials and methods: Cross-sectional analysis of adults in the 2011–2013 National Health Interview Survey.Results: Higher proportions of adults with arthritis had SPD (6.8% vs. 2.4%, depression (19.4% vs. 7.3%, and anxiety (29.3% vs. 16.3% compared to those without. Of the estimated 3.5 million adults with arthritis and SPD, only 39% saw a mental health professional during the year. Adjusted analyses identified the following statistically significant relationships: those who were older (45–64 and ≥65 [vs.18–44], prevalence ratio [PR]=0.8 and 0.4, respectively, less educated (PR=0.5 and 0.7 for high school or less vs. college degree, respectively, and without health insurance coverage (vs. any private, PR=0.7, were less likely to see a mental health professional, whereas the disabled or unemployed (vs. employed, PR=1.6 and 1.5, respectively, and those unable to afford mental health care throughout the year (PR=1.3 were more likely.Conclusion: The high prevalence of SPD, anxiety, and depression in adults with arthritis suggests the need for increased mental health screening, with subsequent referral to mental health professionals or other treatment programs, in that population. Keywords: serious psychological distress, anxiety, depression, access to mental health care, rheumatoid arthritis 

  12. A scoping review of crisis teams managing dementia in older people

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    Streater A

    2017-10-01

    Full Text Available Amy Streater,1,2 Donna Maria Coleston-Shields,2 Jennifer Yates,2 Miriam Stanyon,2 Martin Orrell2 1Research and Development, North East London NHS Foundation Trust, Ilford, 2Institute of Mental Health, University of Nottingham, Nottingham, UK Background: Research on crisis teams for older adults with dementia is limited. This scoping review aimed to 1 conduct a systematic literature review reporting on the effectiveness of crisis interventions for older people with dementia and 2 conduct a scoping survey with dementia crisis teams mapping services across England to understand operational procedures and identify what is currently occurring in practice.Methods: For the systematic literature review, included studies were graded using the Critical Appraisal Skills Programme checklist. For the scoping survey, Trusts across England were contacted and relevant services were identified that work with people with dementia experiencing a mental health crisis.Results: The systematic literature review demonstrated limited evidence in support of crisis teams reducing the rate of hospital admissions, and despite the increase in number of studies, methodological limitations remain. For the scoping review, only half (51.8% of the teams had a care pathway to manage crises and the primary need for referral was behavioral or psychological factors.Conclusion: Evidence in the literature for the effectiveness of crisis teams for older adults with dementia remains limited. Being mainly cohort designs can make it difficult to evaluate the effectiveness of the intervention. In practice, it appears that the pathway for care managing crisis for people with dementia varies widely across services in England. There was a wide range of names given to the provision of teams managing crisis for people with dementia, which may reflect the differences in the setup and procedures of the service. To provide evidence on crisis intervention teams, a comprehensive protocol is required

  13. Alfabetização e letramento: a importância da alfabetização na construção de conhecimentos pelo sujeito na sociedade

    Directory of Open Access Journals (Sweden)

    Juliana Cassia Penaroti

    2011-07-01

    Full Text Available No presente artigo trago os resultados obtidos em minha pesquisa sobre Alfabetização e Letramento,com a temática:A importância da alfabetização na construção de conhecimentos pelo sujeito na sociedade; realizada no período de 14/10/2010 a 22/10/2010, na Escola Municipal de Educação Básica Ana Cristina de Senna, município de Sinop/MT, em uma turma de 1º anono período matutino. Nesta investigação busquei compreender como é sistematizado o processo de alfabetização quanto aos métodos utilizados na aquisição da leitura e escrita pelas crianças, e se tais métodos são aplicados à luz do Letramento. As discussões trazidas na pesquisa são fundamentadas nas teorias da autora Magda Soares e Emília Ferreiro,que nos traz os reflexos de uma alfabetização com letramento na formação do indivíduo, para que o mesmo seja sujeito ativo no meio social. Para obter respostas a minha investigação, utilizei os métodos pesquisa qualitativa e observação participante, por meio de entrevistas com questões abertas e observações em sala, com o professor da turma e três alunos, embasada nos autores Miriam Goldenberg e Antonio Chizzotti, os quais me deram respaldo quanto aos procedimentos investigativos.A referida pesquisa possibilitou compreender a importância de se promover o processo de alfabetização para letramento, afim de que este ultrapasse o ato mecânico de ler e escrever, e seja um instrumento para o sujeito no exercício de sua cidadania.Palavras-chave: educação; alfabetização; letramento; formação do indivíduo; instrumento; cidadania.

  14. Selected abstracts from the Breastfeeding and Feminism International Conference 2016

    Directory of Open Access Journals (Sweden)

    Lisa H. Amir

    2016-10-01

    Full Text Available Table of contents A1. Infant feeding and poverty: a public health perspective in a global context Lisa H. Amir A2. Mothers’ experiences with galactagogues for lactation: an exploratory cross sectional study Alessandra Bazzano, Shelley Thibeau, Katherine P. Theall A3. The motherhood journey and breastfeeding: from self-efficacy to resilience and social stigma Anna Blair, Karin Cadwell A4. Breastfeeding as an evolutionary adaptive behavior Emily A. Bronson A5. Conflict-of-interest in public health policy: as real as that logo on your website Elizabeth C. Brooks A6. Co-opting sisterhood and motherhood: behind the scenes of Similac’s aggressive social media campaigns Jodine Chase A7. The exclusion of women from the definition of exclusive breastfeeding Ellen Chetwynd, Rebecca Costello, Kathryn Wouk A8. Healthy maternity policies in the workplace: a state health department’s experience with the “Bring Your Infant to Work” program Lindsey Dermid-Gray A9. Implications for a paradigm shift: factors related to breastfeeding among African American women Stephanie Devane-Johnson, Cheryl Woods Giscombe, Miriam Labbok A10. Social experiences of breastfeeding: building bridges between research and policy: an ESRC-funded seminar series in the UK Sally Dowling A11. Manager’s perspectives of lactation breaks Melanie Fraser A12. The challenging second night: a dialogue from two perspectives Jane Grassley, Deborah McCarter-Spaulding, Becky Spencer A13. The role of lactation consultants in two council breastfeeding services in Melbourne, Australia – some preliminary impressions Jennifer Hocking, Pranee Liamputtong A14. Integrating social marketing and community engagement concepts in community breastfeeding programs Sheree H. Keitt, Harumi Reis-Reilly A15. What happens before and after the maternity stay? Creating a community-wide Ten Steps approach Miriam Labbok A16. #RVABREASTFEEDS: cultivating a breastfeeding-friendly community Leslie Lytle A17

  15. Quantum Fest 2016 International Conference on Quantum Phenomena, Quantum Control and Quantum Optics

    International Nuclear Information System (INIS)

    2017-01-01

    Department, Cinvestav)Zulema Gress (UPIITA-IPN)The Quantum Fest 2016 would not have been possible without the valuable financial support of the sponsor institutions: Instituto Politécnico Nacional, UPIITA-IPN and Cinvestav.Our thanks to Dr. Alejandro García Guerra, Director de la UPIITA-IPN for endless support and host during the festival.Special thanks to Mmes Berenice León, Rebeca Octaviano and Miriam Lomelí, Secretaries of the festival, for invaluable help in many aspects of the organization, including the design of the posters and distribution of announcements, hotel and flight reservations, and the scheduling of the event. Berenice, Rebeca and Miriam: the Bar Quantum is very grateful to you.The publication of this volume of Journal of Physics: Conference Series has been supported by the Instituto Politécnico Nacional in the framework of the celebration of its 80th Anniversary. We would like to express our gratitude to Lic. Hilda Castro, Subdirectora Administrativa de la UPIITA-IPN for facilitating the administrative duties related with the publication of these Proceedings.The present volume includes only the positively refereed contributions that were submitted by the participants of the festival.Finally, we announce that the Quantum Fest will take place every two years from now on. The eight festival will be celebrated in the facilities of the Physics Department of Cinvestav.Sara Cruz y CruzInstituto Politécnico Nacional, UPIITAMéxico City, April 2017 (paper)

  16. A geoethical approach to the geological and astrobiological exploration and research of the Moon and Mars

    Science.gov (United States)

    Martinez-Frias, Jesus; Horneck, Gerda; de La Torre Noetzel, Rosa; Rull, Fernando

    procedures related to the study of Lunar and Mar-tian meteorites, and also the research, taking into account this new perspective, of the Earth locations which are called terrestrial analogs. 1 UN (1967) Treaty on principles governing the activities of states in the exploration and use of outer space, including the moon and other celestial bodies Article I . U.N. Doc. A/RES/2222/(XXI) (25 Jan 1967). United Nations TIAS No. 6347. 2 Nemec, V. Nemcova, L. (2008) 33rd Inter-national Geological Congress, Oslo, August 6-14th. 3 http://www.bgs.ac.uk/agid/ 4 Martinez-Frias, J. et al. (2009) Bolides and Meteorite Falls, Prague, May 10-15, 14-15. 5 Martinez-Frias, J. et al. (2009) EANA'09, Brussels, 12-14 October 2009. 6 http://tierra.rediris.es/Geoethics Planetary Prot 7 IUCN (2008) http://data.iucn.org/dbtw-wpd/edocs/WCC-4th-004.pdf 8 Cockell, C.S. Hor-neck, G. (2004) Space Policy 20: 291-295. 9 Cockell, C.S. Horneck, G. (2006) Space Policy 22: 256-261.

  17. Integrated orbital time scale of the Valanginian-Hauterivian (Early Cretaceous): Chronological relationships between Paraná-Etendeka LIP, Weissert and Faraoni events

    Science.gov (United States)

    Martinez, Mathieu; Deconinck, Jean-François; Pellenard, Pierre; Riquier, Laurent; Company, Miguel; Moiroud, Mathieu; Reboulet, Stéphane

    2014-05-01

    During the Valanginian and the Hauterivian stages, the Weissert and Faraoni Events recorded global perturbations of the carbon cycle, marine organic matter deposits and rapid ecosystem changes. Both events were successively attributed to the activity of the Paraná-Etendeka Large Igneous Province (LIP). However, due to the scarcity of the radiometric ages available for this time interval, the chronological relationships between these events and the activity of the Paraná-Etendeka LIP remain unclear. Recently, the duration of the Valanginian Stage was calculated using a cyclostratigraphic approach on GSSP candidates and stratotypes (Martinez et al., 2013), but could not be anchored on a radiometric age. Here, we propose a duration assessment of the Hauterivian Stage using a similar cyclostratigraphic approach on the hemipelagic marl-limestone alternations from the La Charce section (Hauterivian GSSP candidate; SE France) and the Río Argos section (Barremian GSSP candidate; SE Spain). This duration could be anchored on an U/Pb age from a tuff level precisely dated using calcareous nannofossils and chemostratigraphy, to provide a refined geological time scale for the Valanginian and the Hauterivian stages. A total of 2000 spectral gamma-ray measurements were performed with a constant 0.20-m sample step. Spectral analyses were performed on the gamma-ray series to detect any sedimentary cycle. The precession, obliquity, 100-kyr and 405-kyr eccentricity cycles were identified by comparing sedimentary to orbital period ratios. The duration of the Hauterivian Stage could be assessed at 5.9 myr, using the 405-kyr eccentricity cycle as a reference. By anchoring the U/Pb age of Aguirre-Urreta et al. (2008) on the orbital time scale provided for the Valanginian-Hauterivian stages, the base of the Valanginian Stage could be dated at -140.2 ± 1.5 Ma, the base of the Hauterivian at -135.1 ± 1.5 Ma and the base of the Barremian at -129.2 ± 1.5 Ma. In addition, the Weissert

  18. Future directions in feedback on second language writing: Overview and research agenda

    Directory of Open Access Journals (Sweden)

    Fiona Hyland

    2010-12-01

    Full Text Available This article provides an overview of the contributions made to this special issue on feedback by the seven papers, examining how they reflect both the growing interest in different areas of research into feedback on writing and the continuing search by teachers for more effective feedback practices. Focusing first on the papers by Van Beuningen, Storch, Evans, Hartshorn and Allen, it discusses how these papers situate written corrective feedback research in the wider area of second language acquisition research and contribute to the debate in feedback research on research design issues. This is followed by an examination of the major findings of the four situated empirical studies by Bitchener, Ma, El-ebyary and Windeatt, and Martinez and Roca, which make up the second section. Echoing the authors of these papers, this article argues that we need more longitudinal naturalistic studies, adopting both cognitive and socio-cultural SLA frameworks to investigate the role of feedback and its impact on individual learners in more depth. Finally some pedagogic implications are discussed, including the need for feedback practices which facilitate students’ abilities to self regulate and evaluate their performance, and the need to raise teachers’ awareness of the different feedback sources and modes of delivery available to them.Este artículo ofrece una revisión de las siete aportaciones incluidas en este número especial sobre feedback, constatando cómo reflejan tanto el creciente interés por el tema en las distintas áreas de investigación como la continua búsqueda de técnicas más efectivas por parte del profesorado. Centrándose en primer lugar en las contribuciones de Van Beuningen, Storch, Evans, Hartshorn y Allen, analiza cómo estos artículos sitúan la investigación sobre feedback en la corrección de trabajos escritos dentro del área más amplia de adquisición de segundas lenguas, contribuyendo al debate, dentro de la investigaci

  19. Mapping Forest Fire Susceptibility in Temperate Mountain Areas with Expert Knowledge. A Case Study from Iezer Mountains, Romanian Carpathians

    Science.gov (United States)

    Mihai, Bogdan; Savulescu, Ionut

    2014-05-01

    help of forestry data, the wind regime data and the topographic features of the mountain area (elevation, slope declivity, slope aspect). The analysis also consider the insolation degree of mountain slopes, that creates favourable conditions for fire propagation between different canopies. These data layers are integrated within a simple GIS analysis in order to intersect the ignition zones with the fire propagation zones in order to obtain the potential areas to be affected by fire. The digital map show three levels of forest fire susceptibility, differenced on the basis of expert knowledge. The map can be validated from the statistical point of view with the polygons of the forest fire affected areas mapped from Landsat TM, ETM+ and OLI satellite imagery. The mapping results could be integrated within the forest management strategies and especially within the forest cadastre and development maps (updated every ten years). The result can confirm that the data gap in terms of forest fire events can be filled with expert knowledge. References Chuvieco, E, Aguado, I., Jurdao, S., Pettinari, M., Yebra, M., Salas, J., Hantson, S., de la Riva, J., Ibarra, P., Rodrigues, M., Echeverria, M., Azqueta, D., Roman, M., Bastarrika, A., Martinez, S., Recondo, C., Zapico, E., Martinez-Vega F.J. (2012) Integrating geospatial information into fire risk assessment, International Journal of Wildland Fire, 2,2, 69-86. Hantson, S., Padilla, M., Corti., D, Chuvieco, E. (2013) Strenghts and weaknesses of MODIS hotspots to characterize Global fire occurence, Remote Sensing of Environment, 131, 1, 152-159. Mihai, B., Savulescu, I.,Sandric, I. (2007) Change detection analysis (1986/2002) for the alpine, subalpine and forest landscape in Iezer Mountains (Southern Carpathians, Romania), Mountain Research and Development, 27, 250-258.

  20. Beta-cell function is associated with metabolic syndrome in Mexican subjects

    Directory of Open Access Journals (Sweden)

    Pérez-Fuentes

    2010-08-01

    Full Text Available Blanca G Baez-Duarte1,3, María Del Carmen Sánchez-Guillén3†, Ricardo Pérez-Fuentes2,3, Irma Zamora-Ginez1,3, Bertha Alicia Leon-Chavez1, Cristina Revilla-Monsalve4, Sergio Islas-Andrade41Posgrado en Ciencias Químicas, Benemérita Universidad Autónoma de Puebla, México; 2Facultad de Medicina, Benemérita Universidad Autónoma de Puebla, México; 3Centro de Investigación Biomédica de Oriente, Instituto Mexicano del Seguro Social, Atlixco, Puebla, México; 4Multidiciplinary Research Group on Diabetes (José Sánchez-Corona, Fernando Guerrero-Romero, Martha Rodriguez-Moran, Agustin Madero, Jorge Escobedo-de-la-Peña, Silvia Flores-Martinez, Esperanza, Martinez-Abundis, Manuel Gonzalez-Ortiz, Alberto Rascon-Pacheco, Margarita Torres-Tamayo, Instituto Mexicano del Seguro Social, México, Distrito Federal, México; †María Del Carmen Sánchez-Guillén passed away on 27 November 2009.Aims: The clinical diagnosis of metabolic syndrome does not find any parameters to evaluate the insulin sensitivity (IS or β-cell function. The evaluation of these parameters would detect early risk of developing metabolic syndrome. The aim of this study is to determine the relationship between β-cell function and presence of metabolic syndrome in Mexican subjects.Material and methods: This study is part of the Mexican Survey on the Prevention of Diabetes (MexDiab Study with headquarters in the city of Puebla, Mexico. The study comprised of 444 subjects of both genders, aged between 18 and 60 years and allocated into two study groups: (1 control group of individuals at metabolic balance without metabolic syndrome and (2 group composed of subjects with metabolic syndrome and diagnosed according to the criteria of the Third Report of the National Cholesterol Education Program Expert Panel on Defection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Anthropometric, biochemical, and clinical assessments were carried out.Results: Average age of the

  1. Quantifying Uncertainty in Estimation of Potential Recharge in Tropical and Temperate Catchments using a Crop Model and Microwave Remote Sensing

    Science.gov (United States)

    Krishnan Kutty, S.; Sekhar, M.; Ruiz, L.; Tomer, S. K.; Bandyopadhyay, S.; Buis, S.; Guerif, M.; Gascuel-odoux, C.

    2012-12-01

    Groundwater recharge in a semi-arid region is generally low, but could exhibit high spatial variability depending on the soil type and plant cover. The potential recharge (the drainage flux just beneath the root zone) is found to be sensitive to water holding capacity and rooting depth (Rushton, 2003). Simple water balance approaches for recharge estimation often fail to consider the effect of plant cover, growth phases and rooting depth. Hence a crop model based approach might be better suited to assess sensitivity of recharge for various crop-soil combinations in agricultural catchments. Martinez et al. (2009) using a root zone modelling approach to estimate groundwater recharge stressed that future studies should focus on quantifying the uncertainty in recharge estimates due to uncertainty in soil water parameters such as soil layers, field capacity, rooting depth etc. Uncertainty in the parameters may arise due to the uncertainties in retrieved variables (surface soil moisture and leaf area index) from satellite. Hence a good estimate of parameters as well as their uncertainty is essential for a reliable estimate of the potential recharge. In this study we focus on assessing the sensitivity of crop and soil types on the potential recharge by using a generic crop model STICS. The effect of uncertainty in the soil parameters on the estimates of recharge and its uncertainty is investigated. The multi-layer soil water parameters and their uncertainty is estimated by inversion of STICS model using the GLUE approach. Surface soil moisture and LAI either retrieved from microwave remote sensing data or measured in field plots (Sreelash et al., 2012) were found to provide good estimates of the soil water properties and therefore both these data sets were used in this study to estimate the parameters and the potential recharge for a combination of soil-crop systems. These investigations were made in two field experimental catchments. The first one is in the tropical semi

  2. Relationship between carbon microstructure, adsorption energy and hydrogen adsorption capacity at different temperatures

    International Nuclear Information System (INIS)

    Jagiello, J.; Thommes, M.

    2005-01-01

    sizes. The highest Qst is observed for the CMS sample having micropores sizes of about 5 A. The SWNT sample shows a lower Qst due to its relatively wide PSD [2], and the non-porous carbon black is characterized by the lowest Qst values. The Qst values calculated from H 2 adsorption isotherms measured at cryogenic temperatures below 1 atmosphere can be used to predict/estimate H 2 adsorption at ambient temperatures under high pressures. Fig 3 shows the H 2 adsorption isotherm on the SWNT sample calculated for 298 K from the low pressure and low temperature (77, 87 K) data using the Clausius-Clapeyron equation and assuming the temperature independence of the Qst values. A good agreement with high-pressure experimental data [3] is observed. Predictions using DFT model will also be discussed during presentation. [1] J. Jagiello, M. Thommes, Carbon 42, 1227, 2004. [2] A. Anson, J. Jagiello, J. B. Parra, M.L. Sanjuan, A. M. Benito, W. K. Maser, M. T. Martinez, J. Phys. Chem. B, 108, 15820, 2004. [3] A. Anson, M. Banham, J. Jagiello, M. A. Callejas, A. M. Benito, W. K. Maser, M. A. Zuttel, P. Sudan, M. T. Martinez, Nanotechnology, 15, 1503, 2004. (authors)

  3. PREFACE: First Latin-American Conference on Bioimpedance (CLABIO 2012)

    Science.gov (United States)

    Bertemes Filho, Pedro

    2012-12-01

    . In making this conference possible, we want to acknowledge our deep appreciation for the financial support of FAPESC (Foundation for Research and Innovation of Santa Catarina), CAPES (Coordination for the Improvement of Higher Level -or Education- Personnel) and also express our sincere thanks to the many individuals who contributed their time and diligence to making this conference possible. Our special thanks go to the Santa Catarina State University for contributing time and effort to organizing the conference. We also wish to express our thanks to Professors Ana Watanabe and Fabricio Noveletto for helping with the registration process, the conference desk and the diverse and sundry details that are the part of any event of this kind. We would like also to thank all of the invited speakers and the members of the Program Committee, and wopuld like to express our gratitude to the Technological Institute of Joinville (FITEJ) for their technical co-sponsorship. We very much appreciate Orjan Martinsen, Uwe Pliquett, Fernando Martinez Seoane, Raul Gonzalez Lima, Marcio Nogueira de Souza and Carlos Augusto Gonzalez Correa for delivering keynote talks at the conference. And we would like to extend an enthusiastic round of thanks to all of our conference authors for their excellent contributions; to all the session chairs for their effort and enthusiasm; and to all the International Program Committee members and referees for their time and expertise in the paper review. Particular thanks go to Emiliano Amarante Veiga and other members of the CLABIO2012 Secretariat and organizing team for their time and outstanding work. List of committees General Chair Professor Pedro Bertemes Filho (Santa Catarina State University) Pedro Bertemes Filho Technical Program Chairs Dr Marcio Nogueira de Souza (Rio de Janeiro Federal University) Local Arrangement Chair Professor Aleksander Paterno (Santa Catarina State University) Professor Fabrício Noveletto (Santa Catarina State University

  4. Effects of different doses of high-speed resistance training on physical performance and quality of life in older women: a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Ramirez-Campillo R

    2016-12-01

    Full Text Available Rodrigo Ramirez-Campillo,1–3 Daniela Diaz,4 Cristian Martinez-Salazar,5 Pablo Valdés-Badilla,6 Pedro Delgado-Floody,5 Guillermo Méndez-Rebolledo,7 Rodrigo Cañas-Jamet,8,9 Carlos Cristi-Montero,10 Antonio García-Hermoso,11 Carlos Celis-Morales,12 Jason Moran,13 Thomas W Buford,14 Leocadio Rodriguez-Mañas,15 Alicia M Alonso-Martinez,16 Mikel Izquierdo16 1Department of Physical Activity Sciences, 2Laboratory of Measurement and Assessment in Sports, Research Nucleus in Health, Physical Activity and Sports, Universidad de Los Lagos, Osorno, 3Unit of Integrative Physiology, Laboratory of Exercise Sciences, MEDS Clinic, Santiago, Chile; 4School of Occupational Therapy, Faculty of Health, Universidad Santo Tomás, Osorno, 5Department of Physical Education, Sport and Recreation, Universidad de La Frontera, 6Institute of Physical Activity and Health, Universidad Autónoma de Chile, Temuco, 7School of Kinesiology, Faculty of Health, University Santo Tomás, Talca, 8Laboratory of Physiology, Department of Biological Sciences, Faculty of Biological Sciences, Universidad Andres Bello, Viña del Mar, 9School of Kinesiology, Faculty of Medicine, Universidad Diego Portales, Santiago, 10IRyS Group, Physical Education School, Pontificia Universidad Católica de Valparaíso, Valparaíso, 11Laboratory of Physical Activity Sciences, Sport and Health, Faculty of Medical Sciences, Universidad de Santiago de Chile, USACH, Santiago, Chile; 12BHF Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, 13Centre for Sports and Exercise Science, School of Biological Sciences, University of Essex, Colchester, UK; 14Department of Aging and Geriatric Research, Institute of Aging, University of Florida, College of Medicine, Gainesville, Florida, USA; 15Division of Geriatric Medicine, University Hospital of Getafe, Madrid, 16Department of Health Sciences, Public University of Navarre, Navarre, Spain

  5. Staff members with 25 years’ service at CERN in 2008

    CERN Multimedia

    2008-01-01

    The 47 staff members who have spent 25 years within CERN in 2008 were invited by the Director-General to a reception in their honour on 24 October. Mr.\tAllen\tDavid John\tAB Dr.\tBailey\tRoger\tAB Mr.\tBlas\tAlfred\tAB Mr.\tBobbio\tPiero\tAB Dr.\tBona\tMaurizio\tSC Mr.\tBrachet\tJean-Pierre\tTS Dr.\tBurckhart\tHelfried\tPH Miss\tButtay\tCatherine\tFI Mr.\tCatherall\tRichard\tAB Mr.\tCoin\tAndré-Yvon\tTS Dr.\tCornelis\tKarel\tAB Dr.\tDavenport\tMartyn\tPH Mr.\tDehavay\tClaude\tAB Mr.\tDenblyden\tJean-Loup\tPH Mr.\tDenis\tBernard\tDSU Mr.\tDuret\tMax\tAT Mr.\tEvans\tJohn\tIT Mrs.\tFavrot\tVéronique\tIT Mr.\tFowler\tAntony\tAB Mrs.\tGalmant\tCatherine\tAB Mr.\tGuillaume\tJean-Claude\tTS Mrs.\tJerdelet\tJocelyne\tDSU Dr.\tKostro\tKrzysztof\tAB Mr.\tKuczerowski\tJoseph\tAB Mr.\tLappe\tJean-Pierre\tTS Mrs.\tLaverrière\tCatherine\tSC Mr.\tLeggiero\tLuigi\tTS Mr.\tManglunki\tDjango\tAB Mr.\tMartens\tReinoud\tIT Mr.\tMartinez\tGeorges\tSC Mr.\tMonchalin\tPhilippe\tSC Mr.\tMoret\tPhilippe\tDSU Mr.\tOlesen\tGert\tPH Mr.\tPasinelli\tSergi...

  6. Phlebotomines (Diptera, Psychodidae in caves of the Serra da Bodoquena, Mato Grosso do Sul State, Brazil

    Directory of Open Access Journals (Sweden)

    Eunice A. B. Galati

    2003-01-01

    Full Text Available The present paper deals with the phlebotomine species captured during the period from January 1998 to June 2000 in 12 caves located in the Serra da Bodoquena, situated in the south central region of Mato Grosso do Sul State, Brazil. Three of the caves are situated further north (in Bodoquena county, seven in the central area (Bonito county and two in the south (Jardim county. These last two caves and three of those in Bonito are located at the west side of the ridge. Eighteen species of phlebotomines were captured within the caves: Brumptomyia avellari (Costa Lima, 1932, Brumptomyia brumpti (Larrousse, 1920, Brumptomyia cunhai (Mangabeira, 1942, Brumptomyia galindoi (Fairchild & Hertig, 1947, Evandromyia corumbaensis (Galati, Nunes, Oshiro & Rego, 1989, Lutzomyia almerioi Galati & Nunes, 1999, Lutzomyia longipalpis (Lutz & Neiva, 1912, Martinsmyia oliveirai (Martins, Falcão & Silva, 1970, Micropygomyia acanthopharynx (Martins, Falcão & Silva, 1962, Micropygomyia peresi (Mangabeira, 1942, Micropygomyia quinquefer (Dyar, 1929, Nyssomyia whitmani (Antunes & Coutinho, 1939, Psathyromyia campograndensis (Oliveira, Andrade-Filho, Falcão & Brazil, 2001, Psathyromyia punctigeniculata (Floch & Abonnenc, 1944, Psathyromyia shannoni (Dyar, 1929, Pintomyia kuscheli (Le Pont, Martinez, Torrez-Espejo & Dujardin, 1998, Sciopemyia sordellii (Shannon & Del Ponte, 1927 and Sciopemyia sp. A total of 29,599 phlebotomine sandflies was obtained. Lutzomyia almerioi was absolutely predominant (91.5% over the other species on both sides of the Bodoquena ridge, with the exception of the southern caves in which it was absent. It presents summer predominance, with nocturnal and diurnal activities. The species breeds in the caves and was captured during daytime both in the dark area and in the mouth of the caves. Martinsmyia oliveirai, the second most frequent sandfly, also presents a summer peak and only predominated over the other species in one cave, in which there

  7. Fotogenia literaria en Carreteras secundarias, de Ignacio Martínez de Pisón: un viaje de ida y vuelta

    Directory of Open Access Journals (Sweden)

    García-Abad García, M. Teresa

    2005-06-01

    Full Text Available The cinema, his synthetic character, and the dialogue that it establishes from the origin with other arts as literature, has not stopped offering a wide space of synergies for the adaptation practice and for the study of confluence areas between image and word. New generations of writers and directors propiciate across their work an opening that, beside integrating the expressive resources of the literature and the screen, consider the text as a productive and plural activity, capable of being spread in a stereophony that postpones its meaning in every process of reading, making it coincide with a practice of writing and creation. Ignacio Martinez de Pisón's literature contains sugerent keys to advance in the dialogue between literature and cinema in current Spanish narrative.El cine, su carácter sintético, y el diálogo que desde el origen establece con otras artes como la literatura, no han dejado de ofrecer un espacio amplio de sinergias para la práctica adaptativa y para la reflexión acerca de los ámbitos de confluencia entre la imagen y la palabra. Las generaciones de escritores y de directores más jóvenes propician a través de su obra una apertura que, además de integrar los recursos expresivos de la literatura y la pantalla, considera al texto como una actividad productiva y plural capaz de diseminarse en una estereofonía que aplaza su significado en cada proceso de lectura haciéndolo coincidir con una práctica de escritura y de creación. La literatura de Martínez de Pisón contiene claves sugerentes para desentrañar este diálogo entre literatura y cine en la narrativa española actual.

  8. Geografía, literatura e ideología en la segunda mitad del siglo XX: las “Guías de España” de Ediciones Destino

    Directory of Open Access Journals (Sweden)

    Arroyo Ilera, Fernando

    2008-12-01

    Full Text Available The Catalonian publishing company Destino published a collection of sixteen guides about different regions and cities of Spain.

    These guides almost covered the whole country and are an important publishing and geographic legacy of the time.

    This type of publications, somewhere between travel books and tourist guides, has not received the praise they deserve.

    The quality of the edition, the graphic material and the high standard of most of the authors (Pla, Baroja, Pemán, Ridruejo, Fuster, Martínez Barbeito, Dolores Medio and others are remarkable.

    Furthermore, these guides were published under General Franco´s regime, a circumstance that has rendered them a very valuable set of documents of cultural Geography.

    La editorial catalana Destino publicó, entre 1943 y 1977 una colección de dieciséis guías de diversas regiones y ciudades de España que comprenden la práctica totalidad del país y constituyen un importante legado editorial, literario y geográfico de la época. Este tipo de publicaciones, intermedias entre los libros de viaje y las guías turísticas propiamente dichas, no cuentan con la atención que merecen, dada la calidad de su edición, con un importante acompañamiento gráfico y la notable importancia de la mayoría de los autores (Pla, Baroja, Pemán, Ridruejo, Fuster, Martinez Barbeito, Dolores Medio, etc.. Además, el tiempo de su publicación, casi coincidente con el que duró el franquismo, convierte a esta colección en un documento de indudable valor para le Geografía cultural.

  9. Medial amygdala lesions selectively block aversive Pavlovian-instrumental transfer in rats.

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    Margaret Grace McCue

    2014-09-01

    Full Text Available Pavlovian conditioned stimuli (CSs play an important role in the reinforcement and motivation of instrumental active avoidance (AA. Conditioned threats can also invigorate ongoing AA responding (aversive Pavlovian-instrumental transfer or PIT. The neural circuits mediating AA are poorly understood, although lesion studies suggest that lateral, basal and central amygdala nuclei, as well as infralimbic prefrontal cortex, make key, and sometimes opposing, contributions. We recently completed an extensive analysis of brain c-Fos expression in good vs. poor avoiders following an AA test (Martinez et al 2013, Learning and Memory. This analysis identified medial amygdala (MeA as a potentially important region for Pavlovian motivation of instrumental actions. MeA is known to mediate defensive responding to innate threats as well as social behaviors, but its role in mediating aversive Pavlovian-instrumental interactions is unknown. We evaluated the effect of MeA lesions on Pavlovian conditioning, Sidman two-way AA conditioning (shuttling and aversive PIT in rats. Mild footshocks served as the unconditioned stimulus in all conditioning phases. MeA lesions had no effect on AA but blocked the expression of aversive PIT and 22 kHz ultrasonic vocalizations in the AA context. Interestingly, MeA lesions failed to affect Pavlovian freezing to discrete threats but reduced freezing to contextual threats when assessed outside of the AA chamber. These findings differentiate MeA from lateral and central amygdala, as lesions of these nuclei disrupt Pavlovian freezing and aversive PIT, but have opposite effects on AA performance. Taken together, these results suggest that MeA plays a selective role in the motivation of instrumental avoidance by general or uncertain Pavlovian threats.

  10. Induction of cell death in a glioblastoma line by hyperthermic therapy based on gold nanorods

    Directory of Open Access Journals (Sweden)

    Fernandez Cabada T

    2012-03-01

    Full Text Available Tamara Fernandez Cabada1,2,*, Cristina Sanchez Lopez de Pablo1,3,*, Alberto Martinez Serrano2, Francisco del Pozo Guerrero1,3, Jose Javier Serrano Olmedo1,3,*, Milagros Ramos Gomez1–3,* 1Centre for Biomedical Technology, Universidad Politecnica de Madrid, Madrid, Spain; 2Centre for Molecular Biology, "Severo Ochoa" Universidad Autonoma de Madrid, Madrid, Spain; 3Biomedical Research Networking Center in Bioengineering Biomaterials and Nanomedicine (CIBER-bbn, Zaragoza, Spain.*These authors contributed equally to this workBackground: Metallic nanorods are promising agents for a wide range of biomedical applications. In this study, we developed an optical hyperthermia method capable of inducing in vitro death of glioblastoma cells.Methods: The procedure used was based on irradiation of gold nanorods with a continuous wave laser. This kind of nanoparticle converts absorbed light into localized heat within a short period of time due to the surface plasmon resonance effect. The effectiveness of the method was determined by measuring changes in cell viability after laser irradiation of glioblastoma cells in the presence of gold nanorods.Results: Laser irradiation in the presence of gold nanorods induced a significant decrease in cell viability, while no decrease in cell viability was observed with laser irradiation or incubation with gold nanorods alone. The mechanism of cell death mediated by gold nanorods during photothermal ablation was analyzed, indicating that treatment compromised the integrity of the cell membrane instead of initiating the process of programmed cell death.Conclusion: The use of gold nanorods in hyperthermal therapies is very effective in eliminating glioblastoma cells, and therefore represents an important area of research for therapeutic development.Keywords: laser irradiation, photothermal therapy, surface plasmon resonance, cancer

  11. Cultural variation in the motivational standards of self-enhancement and self-criticism among bicultural Asian American and Anglo American students.

    Science.gov (United States)

    Zusho, Akane

    2008-10-01

    Recent work on biculturalism has made theoretical and methodological inroads into our understanding of the relation of cultural processes with psychological functioning. Through the use of cultural priming methodologies, investigators have demonstrated that biculturals, or individuals who have experienced and identify with more than one culture, can switch between various "cultural frames of reference" in response to corresponding social cues (Hong, Morris, Chiu, & Benet-Martinez, 2000). Drawing on this work on the cognitive implications of biculturalism, the purpose of the present study was to examine the assumption that independent and interdependent self-construals are associated with the motivational standards of self-enhancement and self-criticism, respectively. More specifically, the effects of differential primes of self on ratings of self-enhancement were investigated in a sample of bicultural Asian American (N = 42) and Anglo American (N = 60) college students; overall, more similarities than differences were noted between the two groups. It was hypothesized that Anglo American students would display marked tendencies toward self-enhancement. However, this hypothesis was not supported. Nevertheless, consistent prime effects were observed for a selected number of ratings related to academic virtues, with those who received an independent-self prime often exhibiting greater self-enhancing tendencies than those who received an interdependent-self prime. For example, participants in the independent-self condition reported on average significantly higher ratings for self-discipline and initiative, as well as the degree to which they perceived themselves to be hard working. Implications for the work on self-representations, motivation, and acculturation are discussed.

  12. Isolating neural correlates of conscious perception from neural correlates of reporting one’s perception

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    Michael A Pitts

    2014-10-01

    Full Text Available To isolate neural correlates of conscious perception (NCCs, a standard approach has been to contrast neural activity elicited by identical stimuli of which subjects are aware versus unaware. Because conscious experience is private, determining whether a stimulus was consciously perceived requires subjective report: e.g., button-presses indicating detection, visibility ratings, verbal reports, etc. This reporting requirement introduces a methodological confound when attempting to isolate NCCs: The neural processes responsible for accessing and reporting one’s percept are difficult to distinguish from those underlying the conscious percept itself. Here, we review recent attempts to circumvent this issue via a modified inattentional blindness paradigm (Pitts, Martinez, & Hillyard, 2012 and present new data from a backward masking experiment in which task-relevance and visual awareness were manipulated in a 2x2 crossed design. In agreement with our previous inattentional blindness results, stimuli that were consciously perceived yet not immediately accessed for report (aware, task-irrelevant condition elicited a mid-latency posterior ERP negativity (~200-240ms, while stimuli that were accessed for report (aware, task-relevant condition elicited additional components including a robust P3b (~380-480ms subsequent to the mid-latency negativity. Overall, these results suggest that some of the NCCs identified in previous studies may be more closely linked with accessing and maintaining perceptual information for reporting purposes than with encoding the conscious percept itself. An open question is whether the remaining NCC candidate (the ERP negativity at 200-240ms reflects visual awareness or object-based attention.

  13. Feature-based attentional modulation increases with stimulus separation in divided-attention tasks.

    Science.gov (United States)

    Sally, Sharon L; Vidnyánsky, Zoltán; Papathomas, Thomas V

    2009-01-01

    Attention modifies our visual experience by selecting certain aspects of a scene for further processing. It is therefore important to understand factors that govern the deployment of selective attention over the visual field. Both location and feature-specific mechanisms of attention have been identified and their modulatory effects can interact at a neural level (Treue and Martinez-Trujillo, 1999). The effects of spatial parameters on feature-based attentional modulation were examined for the feature dimensions of orientation, motion and color using three divided-attention tasks. Subjects performed concurrent discriminations of two briefly presented targets (Gabor patches) to the left and right of a central fixation point at eccentricities of +/-2.5 degrees , 5 degrees , 10 degrees and 15 degrees in the horizontal plane. Gabors were size-scaled to maintain consistent single-task performance across eccentricities. For all feature dimensions, the data show a linear increase in the attentional effects with target separation. In a control experiment, Gabors were presented on an isoeccentric viewing arc at 10 degrees and 15 degrees at the closest spatial separation (+/-2.5 degrees ) of the main experiment. Under these conditions, the effects of feature-based attentional effects were largely eliminated. Our results are consistent with the hypothesis that feature-based attention prioritizes the processing of attended features. Feature-based attentional mechanisms may have helped direct the attentional focus to the appropriate target locations at greater separations, whereas similar assistance may not have been necessary at closer target spacings. The results of the present study specify conditions under which dual-task performance benefits from sharing similar target features and may therefore help elucidate the processes by which feature-based attention operates.

  14. Deglacial Western Equatorial Pacific pCO2 Reconstruction Using Boron Isotopes of Planktonic Foraminiferas

    Science.gov (United States)

    Kubota, K.; Yokoyama, Y.; Ishikawa, T.; Sagawa, T.; Ikehara, M.; Yamazaki, T.

    2017-12-01

    During the last deglaciation (ca. 19 - 11 ka), partial pressure of CO2 (pCO2) of the atmosphere increased by 80 μatm. Many paleoceanographers point out that the ocean had played an important role in atmospheric CO2 rise, since the ocean have 60 times larger capacity to store carbon compared to the atmosphere. However, evidence on where carbon was transferred from the ocean to the atmosphere is still lacking, hampering our understanding of global carbon cycles in glacial-interglacial timescales. Boron isotope of skeletons of marine calcifying organisms such as corals and foraminiferas can pin down where CO2 source/sink existed, because boron isotopes of marine calcium carbonates is dependent on seawater pH, from which pCO2 of the past seawater can be reconstructed. In previous studies using the boron isotope teqnique, Martinez-Boti et al. (2015, Nature) and Kubota et al. (2014, Scientific Reports) revealed that central and eastern parts of the equatorial Pacific acted as a CO2 source (i.e., CO2 emission) during the last deglaciation, suggesting the equatorial Pacific's contribution to atmospheric CO2 rise. However, some conflicting results have been confirmed in a marine sediment record from the western part of the equatorial Pacific (Palmer & Pearson, 2003, Science), making the conclusion elusive. In this presentation, we will show new results of Mg/Ca, oxygen isotope, and boron isotope measurements during the last 35 ka on two species of surface dwelling foraminiferas (Globigerinoides ruber and G. sacculifer) which was hand-picked separatedly from a well-dated marine sediment core recovered from the West Caroline Basin (KR05-15 PC01) (Yamazaki et al., 2008, GRL). From the new records, we will discuss how the equatorial Pacific behaved during the last deglaciation and how it related to the global carbon cycles.

  15. The Time Scale of Recombination Rate Evolution in Great Apes

    Science.gov (United States)

    Stevison, Laurie S.; Woerner, August E.; Kidd, Jeffrey M.; Kelley, Joanna L.; Veeramah, Krishna R.; McManus, Kimberly F.; Bustamante, Carlos D.; Hammer, Michael F.; Wall, Jeffrey D.

    2016-01-01

    Abstract We present three linkage-disequilibrium (LD)-based recombination maps generated using whole-genome sequence data from 10 Nigerian chimpanzees, 13 bonobos, and 15 western gorillas, collected as part of the Great Ape Genome Project (Prado-Martinez J, et al. 2013. Great ape genetic diversity and population history. Nature 499:471–475). We also identified species-specific recombination hotspots in each group using a modified LDhot framework, which greatly improves statistical power to detect hotspots at varying strengths. We show that fewer hotspots are shared among chimpanzee subspecies than within human populations, further narrowing the time scale of complete hotspot turnover. Further, using species-specific PRDM9 sequences to predict potential binding sites (PBS), we show higher predicted PRDM9 binding in recombination hotspots as compared to matched cold spot regions in multiple great ape species, including at least one chimpanzee subspecies. We found that correlations between broad-scale recombination rates decline more rapidly than nucleotide divergence between species. We also compared the skew of recombination rates at centromeres and telomeres between species and show a skew from chromosome means extending as far as 10–15 Mb from chromosome ends. Further, we examined broad-scale recombination rate changes near a translocation in gorillas and found minimal differences as compared to other great ape species perhaps because the coordinates relative to the chromosome ends were unaffected. Finally, on the basis of multiple linear regression analysis, we found that various correlates of recombination rate persist throughout the African great apes including repeats, diversity, and divergence. Our study is the first to analyze within- and between-species genome-wide recombination rate variation in several close relatives. PMID:26671457

  16. Retraction of articles by Dr M. Aramli.

    Science.gov (United States)

    2018-06-01

    The below articles published online on Wiley Online Library (wileyonlinelibrary.com) have been retracted by agreement between the submitting author, Mohammad Sadegh Aramli, the Editor-in-Chief, Heriberto Rodriguez-Martinez, and Blackwell Verlag GmbH. After a thorough investigation, there is strong evidence to indicate that the peer review of these papers was compromised. The identities of the reviewers were unable to be verified, and it is believed that these papers were accepted based on recommendations from reviewers not suitably qualified. REFERENCES Aramli, M. (2014). ATP content, oxidative stress and motility of beluga (Huso huso) semen: Effect of short-term storage. Reproduction in Domestic Animals, 49, 636-640. https://doi.org/10.1111/rda.12339 Aramli, M., Nazari, R., & Gharibi, M. (2015), Effect of post-thaw storage time on motility and fertility of cryopreserved beluga sturgeon (Huso huso) sperm. Reproduction in Domestic Animals, 50, 349-352. https://doi.org/10.1111/rda.12484 Aramli, M., Golshahi, K., Nazari, R., Golpour, A., & Aramli, S. (2016). Influence of glutamine supplementation on motility and fertilization success of frozen-thawed persian sturgeon (Acipenser persicus) sperm. Reproduction in Domestic Animals, 51, 474-477. https://doi.org/10.1111/rda.12704 Aramli, M., Golshahi, K., Banan, A., & Sotoudeh, E. (2016). Reliable collection of Caspian brown trout (Salmo trutta caspius) sperm using a catheter. Reproduction in Domestic Animals, 51, 831-834. https://doi.org/10.1111/rda.12740 Aramli, M., Nazari, R., Aramli, S., & Nouri, H. (2017). Motility and oxidative-antioxidant capacity of Huso huso semen, stored at -80°C. Reproduction in Domestic Animals, 52, 170-173. https://doi.org/10.1111/rda.12814. © 2018 Blackwell Verlag GmbH.

  17. Treatment of Oil & Gas Produced Water.

    Energy Technology Data Exchange (ETDEWEB)

    Dwyer, Brian P. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-02-01

    Production of oil and gas reserves in the New Mexico Four Corners Region results in large volumes of "produced water". The common method for handling the produced water from well production is re-injection in regulatory permitted salt water disposal wells. This is expensive (%7E $5/bbl.) and does not recycle water, an ever increasingly valuable commodity. Previously, Sandia National Laboratories and several NM small business tested pressure driven membrane-filtration techniques to remove the high TDS (total dissolved solids) from a Four Corners Coal Bed Methane produced water. Treatment effectiveness was less than optimal due to problems with pre-treatment. Inadequate pre-treatment allowed hydrocarbons, wax and biological growth to foul the membranes. Recently, an innovative pre-treatment scheme using ozone and hydrogen peroxide was pilot tested. Results showed complete removal of hydrocarbons and the majority of organic constituents from a gas well production water. ACKNOWLEDGEMENTS This report was made possible through funding from the New Mexico Small Business Administration (NMSBA) Program at Sandia National Laboratories. Special thanks to Juan Martinez and Genaro Montoya for guidance and support from project inception to completion. Also, special thanks to Frank McDonald, the small businesses team POC, for laying the ground work for the entire project; Teresa McCown, the gas well owner and very knowledgeable- fantastic site host; Lea and Tim Phillips for their tremendous knowledge and passion in the oil & gas industry.; and Frank Miller and Steve Addleman for providing a pilot scale version of their proprietary process to facilitate the pilot testing.

  18. Modeling of bubble break-up in stirred tanks

    Directory of Open Access Journals (Sweden)

    Živković Goran

    2004-01-01

    Full Text Available The Lagrangian code LAG3D for dispersed phase flow modeling was implemented with the introduction of bubble break-up model. The research was restricted on bubbles with diameter less than 2 mm, i.e. bubbles which could be treated as spheres. The model was developed according to the approach of Martinez-Bazan model. It was rearranged and adjusted for the use in the particular problem of flow in stirred tanks. Developed model is stochastic one, based on the assumption that shear in the flow induces the break of the bubble. As a dominant parameter a dissipation of the turbulent kinetic energy was used. Computations were performed for two different types of the stirrer: Rushton turbine, and Pitch blade turbine. The geometry of the tank was kept constant (four blades. Two different types of liquids with very big difference in viscosity were used, i.e. silicon oil and dimethylsulfoxide, in order to enable computation of the flow in turbulent regime as well. As a parameter of the flow, the number of rotations of the stirrer was varying. As a result of the computation the fields of velocity of both phases were got, as well as the fields of bubble concentration bubble mean diameter and bubble Sauter diameter. To estimate the influence of the break-up model on the processes in the stirred tank a computations with and without this model were performed and compared. A considerable differences were found not only in the field of bubble diameter, but also in the field of bubble concentration. That confirmed a necessity of the introduction of such model. A comparison with the experiments performed with phase Doppler anemometry technique showed very good agreement in velocity and concentration profiles of the gas phase. The results for the average bubble diameter are qualitatively the same, but in almost all computations about 20% smaller bubble diameter was got than in the measurements.

  19. Evaluation of a minimally invasive procedure for sacroiliac joint fusion – an in vitro biomechanical analysis of initial and cycled properties

    Directory of Open Access Journals (Sweden)

    Lindsey DP

    2014-05-01

    Full Text Available Derek P Lindsey,1 Luis Perez-Orribo,2 Nestor Rodriguez-Martinez,2 Phillip M Reyes,2 Anna Newcomb,2 Alexandria Cable,2 Grace Hickam,2 Scott A Yerby,1 Neil R Crawford21SI-BONE, Inc., San Jose, CA, USA; 2Spinal Biomechanics Research Laboratory, Barrow Neurological Institute, St Joseph's Hospital and Medical Center, Phoenix, AZ, USAIntroduction: Sacroiliac (SI joint pain has become a recognized factor in low back pain. The purpose of this study was to investigate the effect of a minimally invasive surgical SI joint fusion procedure on the in vitro biomechanics of the SI joint before and after cyclic loading.Methods: Seven cadaveric specimens were tested under the following conditions: intact, posterior ligaments (PL and pubic symphysis (PS cut, treated (three implants placed, and after 5,000 cycles of flexion–extension. The range of motion (ROM in flexion–extension, lateral bending, and axial rotation was determined with an applied 7.5 N • m moment using an optoelectronic system. Results for each ROM were compared using a repeated measures analysis of variance (ANOVA with a Holm–Šidák post-hoc test.Results: Placement of three fusion devices decreased the flexion–extension ROM. Lateral bending and axial rotation were not significantly altered. All PL/PS cut and post-cyclic ROMs were larger than in the intact condition. The 5,000 cycles of flexion–extension did not lead to a significant increase in any ROMs.Discussion: In the current model, placement of three 7.0 mm iFuse Implants significantly decreased the flexion–extension ROM. Joint ROM was not increased by 5,000 flexion–extension cycles.Keywords: biomechanics, iliosacral, arthrodesis, cadaver

  20. Quaternary Geology and Liquefaction Susceptibility, Napa, California 1:100,000 Quadrangle: A Digital Database

    Science.gov (United States)

    Sowers, Janet M.; Noller, Jay S.; Lettis, William R.

    1998-01-01

    Earthquake-induced ground failures such as liquefaction have historically brought loss of life and damage to property and infrastructure. Observations of the effects of historical large-magnitude earthquakes show that the distribution of liquefaction phenomena is not random. Liquefaction is restricted to areas underlain by loose, cohesionless sands and silts that are saturated with water. These areas can be delineated on the basis of thorough geologic, geomorphic, and hydrologic mapping and map analysis (Tinsley and Holzer, 1990; Youd and Perkins, 1987). Once potential liquefaction zones are delineated, appropriate public and private agencies can prepare for and mitigate seismic hazard in these zones. In this study, we create a liquefaction susceptibility map of the Napa 1:100,000 quadrangle using Quaternary geologic mapping, analysis of historical liquefaction information, groundwater data, and data from other studies. The study is atterned after state-of-the-art studies by Youd (1973) Dupre and Tinsley (1980) and Dupre (1990) in the Monterey-Santa Cruz area, Tinsley and others (1985) in the Los Angeles area, and Youd and Perkins (1987) in San Mateo County, California. The study area comprises the northern San Francisco Metropolitan Area, including the cities of Santa Rosa, Vallejo, Napa, Novato, Martinez, and Fairfield (Figure 1). Holocene estuarine deposits, Holocene stream deposits, eolian sands, and artificial fill are widely present in the region (Helley and Lajoie, 1979) and are the geologic materials of greatest concern. Six major faults capable of producing large earthquakes cross the study area, including the San Andreas, Rodgers Creek, Hayward, West Napa, Concord, and Green Valley faults (Figure 1).

  1. Cardiac cachexia and muscle wasting: definition, physiopathology, and clinical consequences

    Directory of Open Access Journals (Sweden)

    Okoshi MP

    2014-11-01

    Full Text Available Marina P Okoshi,1 Fernando G Romeiro,1 Paula F Martinez,1,2 Silvio A Oliveira Jr,1,2 Bertha F Polegato,1 Katashi Okoshi11Internal Medicine Department, Botucatu Medical School, Sao Paulo State University, UNESP, Sao Paulo, Brazil; 2School of Physiotherapy, Federal University of Mato Grosso do Sul, Campo Grande, BrazilAbstract: Cachexia and muscle wasting are frequently observed in heart failure patients. Cachexia is a predictor of reduced survival, independent of important parameters such as age, heart failure functional class, and functional capacity. Muscle and fat wasting can also predict adverse outcome during cardiac failure. Only more recently were these conditions defined in International Consensus. Considering that heart failure is an inflammatory disease, cardiac cachexia has been diagnosed by finding a body weight loss >5%, in the absence of other diseases and independent of other criteria. Muscle wasting has been defined as lean appendicular mass corrected for height squared of 2 standard deviations or more below the mean for healthy individuals between 20 years and 30 years old from the same ethnic group. The etiology of heart failure-associated cachexia and muscle wasting is multifactorial, and the underlying physiopathological mechanisms are not completely understood. The most important factors are reduced food intake, gastrointestinal alterations, immunological activation, neurohormonal abnormalities, and an imbalance between anabolic and catabolic processes. Cachexia and muscle wasting have clinical consequences in several organs and systems including the gastrointestinal and erythropoietic systems, and the heart, previously affected by the primary disease. We hope that a better understanding of the mechanisms involved in their physiopathology will allow the development of pharmacological and nonpharmacological therapies to effectively prevent and treat heart failure-induced cachexia and muscle wasting before significant body

  2. Water radiological sanitary control of Veracruz State; Control sanitario radiologico de agua del Estado de Veracruz

    Energy Technology Data Exchange (ETDEWEB)

    Carreon G, E.; Vazquez C, J. A.; Aguilar P, M. del C.; Parissi C, A., E-mail: eulaliacarreon@gmail.com [Laboratorio Estatal de Salud Publica, Eucalipto Mza. 12, Lote 7, Corredor Industrial Bruno Pagliai, 91697 Veracruz (Mexico)

    2014-10-15

    This work is carried out in Veracruz State covering over 11 jurisdictions of the State (Panuco, Tuxpan, Poza Rica, Martinez de la Torre, Xalapa, Cordoba, Orizaba, Veracruz, Cosamaloapan, San Andres Tuxtla and Coatzacoalcos). The sampling was realized in a period from 2009 to 2013 analyzing home drinking water, supply sources and wells, the sampling was done by the sanitary checkers of different jurisdictions with approved methods and the methodology was validated at the State Laboratory of Public Health. 1637 samples were analyzed by counting equipment Tennelec Canberra series 5 and a gas supply system P-10 with calibration curves for alpha and gross beta. The results of measurements ranging from 0.07 to 0.25 Bq/L in the activity concentration gross alpha annual average, an gross beta were from 0.12 to 0.17 Bq/L in the activity concentration gross beta annual average, and with a concentration range of alpha activity up to 0.62 and a minimum 0.02, and the concentration of beta activity of a maximum value 1.54 and a minimum 0.02, taking also as resulted in five years of analysis only 1.16% of the analyzed samples (19 samples) showed a value of alpha activity concentration above the minimum detectable concentration and 62.43% (1022 samples) of the analyzed samples showed a value of beta activity concentration above the minimum detectable concentration, is also clear that the results of the sanitary jurisdictions of Panuco and Tuxpan not have corresponding activity values for the years 2009, 2011-2013 except 2010. We can conclude that the regular measurements of alpha and gross beta activity in water are invaluable for timely detection of radioactive contamination. (Author)

  3. VizieR Online Data Catalog: AMIGA sample: CO properties (Lisenfeld+, 2017)

    Science.gov (United States)

    Lisenfeld, U.; Alatalo, K.; Zucker, C.; Appleton, P. N.; Gallagher, S.; Guillard, P.; Johnson, K.

    2017-09-01

    Our sample is based on the catalog of Zucker et al. (2016, Cat. J/ApJ/821/113), which presents WISE data for 652 galaxies in 163 compact groups, of which 428 galaxies have reliable photometry (S/N> 2 in all bands). We searched the literature for all existing CO data for this Zucker et al. (2016, Cat. J/ApJ/821/113) subsample (294 galaxies) and obtained CO measurements for 102 HCG galaxies (Verdes-Montenegro et al., 1998ApJ...497...89V; Leon et al., 1998A&A...330...37L; Martinez-Badenes et al., 2012, Cat. J/A+A/540/A96; Lisenfeld et al., 2014, Cat. J/A+A/570/A24) and for two RSCG galaxies (Mirabel et al., 1990A&A...236..327M; Wiklind et al., 1995A&A...297..643W, NGC 232 and NGC 2831). The observations were carried out with the Institut de Radioastronomie Millimetrique (IRAM) 30m telescope, Five College Radio Telescope, Swedish-ESO Submillimetre Telescope (SEST), and Kitt Peak Radio Telescope with single pointings at the central position for most cases. To supplement the CO data for these 104 galaxies from the literature, as part of this study we observed the redshifted CO(1-0) line for an additional 27 galaxies. We observed an additional 27 galaxies in CGs between January and April 2017 with the IRAM 30m telescope on Pico Veleta. We selected the sources, based on their WISE colors, as preferentially canyon or IRTZ objects. (1 data file).

  4. Estimation of erosion and sedimentation yield in the Ucayali river basin, a Peruvian tributary of the Amazon River, using ground and satellite methods

    Science.gov (United States)

    Santini, William; Martinez, Jean-Michel; Guyot, Jean-Loup; Espinoza, Raul; Vauchel, Philippe; Lavado, Waldo

    2014-05-01

    Since 2003, the works of HYBAM observatory (www.ore-hybam.org) has allowed to quantify with accuracy, precision and over a long period Amazon's main rivers discharges and sediments loads. In Peru, a network of 8 stations is regularly gauged and managed in association with the national meteorological and Hydrological service (SENAMHI), the UNALM (National Agrological University of La Molina) and the National Water Agency (ANA). Nevertheless, some current processes of erosion and sedimentation in the foreland basins are still little known, both in volumes and in localization. The sedimentary contributions of Andean tributaries could be there considerable, masking a very strong sedimentation in subsidence zones localized between the control points of the HYBAM's network. The development of spatial techniques such as the Altimetry and reflectance measurement allows us today to complete the ground's network: HYBAM's works have allowed establishing a relation between surface concentration and reflectance in Amazonian rivers (Martinez et al., 2009, Espinoza et al., 2012) and reconstituting water levels series (Calmant et al., 2006, 2008). If the difficulty of calibration of these techniques increases towards the upstream, their use can allow a first characterization of the tributaries contributions and sedimentation zones. At world level, erosion and sedimentation yields in the upper Ucayali are exceptional, favored by a marked seasonality in this region (Espinoza et al., 2009, Lavado, 2010, Pépin et al., 2010) and the presence of cells of extreme precipitation ("Hotspots") (Johnson et al., 1976, Espinoza et al, 2009a). The upper Ucayali drainage basin is a Piggyback where the River run with a low slope, parallel to the Andean range, deposing by gravity hundred millions a year of sands, silts and clays. In this work, we thus propose an estimation of sedimentation and erosion yield in the Ucayali river basin using ground and satellite methods.

  5. Bismuth oxide aqueous colloidal nanoparticles inhibit Candida albicans growth and biofilm formation

    Directory of Open Access Journals (Sweden)

    Hernandez-Delgadillo R

    2013-04-01

    Full Text Available Rene Hernandez-Delgadillo,1 Donaji Velasco-Arias,3 Juan Jose Martinez-Sanmiguel,2 David Diaz,3 Inti Zumeta-Dube,3 Katiushka Arevalo-Niño,1 Claudio Cabral-Romero2 1Facultad de Ciencias Biológicas, Instituto de Biotecnologia, Universidad Autonoma de Nuevo Leon, UANL, Monterrey, Mexico; 2Facultad de Odontología, Universidad Autonoma de Nuevo Leon, UANL, Monterrey, México; 3Facultad de Quimica, Universidad Nacional Autonoma de Mexico, UNAM, Distrito Federal, México Abstract: Multiresistance among microorganisms to common antimicrobials has become one of the most significant concerns in modern medicine. Nanomaterials are a new alternative to successfully treat the multiresistant microorganisms. Nanostructured materials are used in many fields, including biological sciences and medicine. Recently, it was demonstrated that the bactericidal activity of zero-valent bismuth colloidal nanoparticles inhibited the growth of Streptococcus mutans; however the antimycotic potential of bismuth nanostructured derivatives has not yet been studied. The main objective of this investigation was to analyze the fungicidal activity of bismuth oxide nanoparticles against Candida albicans, and their antibiofilm capabilities. Our results showed that aqueous colloidal bismuth oxide nanoparticles displayed antimicrobial activity against C. albicans growth (reducing colony size by 85% and a complete inhibition of biofilm formation. These results are better than those obtained with chlorhexidine, nystatin, and terbinafine, the most effective oral antiseptic and commercial antifungal agents. In this work, we also compared the antimycotic activities of bulk bismuth oxide and bismuth nitrate, the precursor metallic salt. These results suggest that bismuth oxide colloidal nanoparticles could be a very interesting candidate as a fungicidal agent to be incorporated into an oral antiseptic. Additionally, we determined the minimum inhibitory concentration for the synthesized

  6. Natural resource damage assessments for oil spills: Status of rules and application to recent oil spills

    International Nuclear Information System (INIS)

    Robilliard, G.A.; Winfield, T.P.; Lebednik, P.A.; Markarian, R.K.

    1992-01-01

    The natural resource damage assessment (NRDA) process is based on the concept that all natural resources managed by government agencies or Indian tribes (trustees) are available to the public for its use and enjoyment. These resources have an economic value that can be affected by a spill of oil or other chemicals. The spiller or potentially responsible party (PRP) is responsible to the public, through the trustees, for paying damages and for restoration of the resource. The NRDA process should also determine the appropriate means of restoration, provide a cost for doing so and for conducting the NRDA, and should implement the appropriate restoration activities. The legal and regulatory authority behind NRDA in the USA is explained and reasons why PRPs should be concerned about NRDAs in the context of oil spills are presented. US Department of the Interior regulations describe two procedures for implementing a NRDA. A simplified procedure intended for small spills uses a computer model to generate a damage value. A more thorough and complicated procedure involves a number of phases and steps within the phases, and may include field sampling, data collection and analysis, and detailed evaluation of restoration alternatives. The NRDA experience in oil spills to date is reviewed and the future of NRDA is assessed. Examples cited include the 1988 Shell Oil spill from the Martinez Refinery, the Exxon Bayway pipeline leak of 1990, the Mega Borg spill in the Texas offshore, and the Exxon Valdez spill. It is speculated that trustees will focus on the NRDA process as a cooperative one that includes the trustees and PRPs, with the ultimate goal being restoration of the foregone services provided by natural resources. 5 refs., 1 fig

  7. La morfologia i els seus conceptes en l'ensenyament secundari: tractaments habituals | Morphology and its Concepts in Secondary Education: Common Treatments

    Directory of Open Access Journals (Sweden)

    Abelard Saragossà

    2015-05-01

    Full Text Available Resum Este article descriu les anomalies metodològiques més freqüents que apareixen en l’ensenyament secundari quan tracta els conceptes de la morfologia (o flexió, o accidents gramaticals. En la concepció històrica, es reduïx a sis nocions: gènere, nombre i cas (nom; temps i concordança (verb; comparació i concordança (adjectiu. Després d’exposar què tenen en comú les dos maneres d’expressar-los ({pensaré contra I will think}, {longer contra més llarg}, el treball mostra que els manuals actuals contenen dos idees de la morfologia, diferents i incompatibles entre elles: la tradicional i aquella en què el morfema (unitat significativa implica tota la lingüística excepte el fonema (unitat no significativa. Este article es complementa amb el de Sara Martínez Fraile, que oferix una alternativa. Abstract This article describes methodological anomalies that appear frequently in secondary school when the concepts of morphology (or inflection, or grammatical accidents are treated. Morphological concepts are six concepts in historical conception: gender, number and case (name; time and agreement (verb; comparison and agreement (adjective. After exposing what the two ways of expressing them have in common ({pensaré against I will think}, {longer against més llarg}, the present study shows that manuals contain two conceptions of morphology, which are different and incompatible: the traditional one and the one in which the morpheme (meaningful unit involves all language except the phoneme (unit without meaning. This article is complemented by Sara Martinez Fraile, which offers an alternative.

  8. De mitos y realidades (respuesta a Luciano Martínez

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    José Luis Coraggio

    2009-10-01

    Full Text Available Este artículo constituye la respuesta del autor al comentario crítico realizado, en esta misma sección, por Luciano Martínez, en la pasada edición. El autor sostiene que la economía social y solidaria como un ámbito en construcción, que alberga a diversas vertientes que intentan avanzar hacia otra economía. Este carácter si bien puede albergar dudas, no debe transformase en un fatalismo inmovilizador, que permite la actualización constante del libre mercado como institución hegemónica. Antes que una utopía a denunciar desde una visión “realista”, se trata de construir una economía que combine mecanismos de mercado regulados socio-políticamente y relaciones de reciprocidad y redistribución. El texto explora, en pos de la argumentación, algunos de los elementos que conforman la economía social y solidaria.This article represents the author's response to critical commentary made in this section in the last edition by Luciano Martinez. The author maintains that the social and solidarity economy is a sphere under construction, in which several strands can be found. All of these approaches aim to move towards a different type of economy. This character as a developing realm can prompt doubts; this, however, should not lead to a paralyzing fatalism which allows the constant updating of the free market as a hegemonic institution. Far from a utopia to be denounced from a “realistic” viewpoint of economy, its concerns the construction of an economy that combines socio-politically regulated market mechanisms as well as relations of reciprocity and redistribution. The text also explores some of the elements that make up the solidarity and social economy.

  9. Mental and Emotional Self-Help Technology Apps: Cross-Sectional Study of Theory, Technology, and Mental Health Behaviors.

    Science.gov (United States)

    Crookston, Benjamin T; West, Joshua H; Hall, P Cougar; Dahle, Kaitana Martinez; Heaton, Thomas L; Beck, Robin N; Muralidharan, Chandni

    2017-10-17

    Mental and emotional self-help apps have emerged as potential mental illness prevention and treatment tools. The health behavior theory mechanisms by which these apps influence mental health-related behavior change have not been thoroughly examined. The objective of this study was to examine the association between theoretical behavior change mechanisms and use of mental and emotional self-help apps and whether the use of such apps is associated with mental health behaviors. This study utilized a cross-sectional survey of 150 users of mental or emotional health apps in the past 6 months. Survey questions included theory-based items, app engagement and likeability items, and behavior change items. Stata version 14 was used to calculate all statistics. Descriptive statistics were calculated for each of the demographic, theory, engagement, and behavior variables. Multiple regression analysis was used to identify factors associated with reported changes in theory and separately for reported changes in actual behavior after controlling for potentially confounding variables. Participants reported that app use increased their motivation, desire to set goals, confidence, control, and intentions to be mentally and emotionally healthy. Engagement (Ptheory items, whereas perceived behavior change was positively associated with theory (Ptheory items. Future efforts should consider the value of impacting key theoretical constructs when designing mental and emotional health apps. As apps are evaluated and additional theory-based apps are created, cost-effective self-help apps may become common preventative and treatment tools in the mental health field. ©Benjamin T Crookston, Joshua H West, P Cougar Hall, Kaitana Martinez Dahle, Thomas L Heaton, Robin N Beck, Chandni Muralidharan. Originally published in JMIR Mental Health (http://mental.jmir.org), 17.10.2017.

  10. Water radiological sanitary control of Veracruz State

    International Nuclear Information System (INIS)

    Carreon G, E.; Vazquez C, J. A.; Aguilar P, M. del C.; Parissi C, A.

    2014-10-01

    This work is carried out in Veracruz State covering over 11 jurisdictions of the State (Panuco, Tuxpan, Poza Rica, Martinez de la Torre, Xalapa, Cordoba, Orizaba, Veracruz, Cosamaloapan, San Andres Tuxtla and Coatzacoalcos). The sampling was realized in a period from 2009 to 2013 analyzing home drinking water, supply sources and wells, the sampling was done by the sanitary checkers of different jurisdictions with approved methods and the methodology was validated at the State Laboratory of Public Health. 1637 samples were analyzed by counting equipment Tennelec Canberra series 5 and a gas supply system P-10 with calibration curves for alpha and gross beta. The results of measurements ranging from 0.07 to 0.25 Bq/L in the activity concentration gross alpha annual average, an gross beta were from 0.12 to 0.17 Bq/L in the activity concentration gross beta annual average, and with a concentration range of alpha activity up to 0.62 and a minimum 0.02, and the concentration of beta activity of a maximum value 1.54 and a minimum 0.02, taking also as resulted in five years of analysis only 1.16% of the analyzed samples (19 samples) showed a value of alpha activity concentration above the minimum detectable concentration and 62.43% (1022 samples) of the analyzed samples showed a value of beta activity concentration above the minimum detectable concentration, is also clear that the results of the sanitary jurisdictions of Panuco and Tuxpan not have corresponding activity values for the years 2009, 2011-2013 except 2010. We can conclude that the regular measurements of alpha and gross beta activity in water are invaluable for timely detection of radioactive contamination. (Author)

  11. The use of quartz crystal microbalance with dissipation (QCM-D for studying nanoparticle-induced platelet aggregation

    Directory of Open Access Journals (Sweden)

    Santos-Martinez MJ

    2012-01-01

    Full Text Available Maria Jose Santos-Martinez1–3, Iwona Inkielewicz-Stepniak1,4, Carlos Medina1, Kamil Rahme5,6, Deirdre M D'Arcy1, Daniel Fox3, Justin D Holmes3,5, Hongzhou Zhang3, Marek Witold Radomski3,51School of Pharmacy and Pharmaceutical Sciences, 2School of Medicine, 3Center for Research on Adaptive Nanostructures and Nanodevices, Trinity College Dublin, Dublin, Ireland; 4Department of Medicinal Chemistry, Medical University of Gdansk, Gdansk, Poland; 5Materials and Supercritical Fluids Group, Department of Chemistry and the Tyndall National Institute, University College Cork, Cork, Ireland; 6Department of Sciences, Faculty of Natural and Applied Science, Notre Dame University, Zouk Mosbeh, LebanonAbstract: Interactions between blood platelets and nanoparticles have both pharmacological and toxicological significance and may lead to platelet activation and aggregation. Platelet aggregation is usually studied using light aggregometer that neither mimics the conditions found in human microvasculature nor detects microaggregates. A new method for the measurement of platelet microaggregation under flow conditions using a commercially available quartz crystal microbalance with dissipation (QCM-D has recently been developed. The aim of the current study was to investigate if QCM-D could be used for the measurement of nanoparticle-platelet interactions. Silica, polystyrene, and gold nanoparticles were tested. The interactions were also studied using light aggregometry and flow cytometry, which measured surface abundance of platelet receptors. Platelet activation was imaged using phase contrast and scanning helium ion microscopy. QCM-D was able to measure nanoparticle-induced platelet microaggregation for all nanoparticles tested at concentrations that were undetectable by light aggregometry and flow cytometry. Microaggregates were measured by changes in frequency and dissipation, and the presence of platelets on the sensor surface was confirmed and imaged by

  12. El Vignola del Colegio de Arquitectos de Valencia y sus retablos de traza sevillana: Juan Martínez Montañés

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    Navarrete Prieto, Benito

    2005-09-01

    Full Text Available Three drawings of altarpieces executed by the Sevillian sculptor Juan Martinez Montañés, preserved in the copy of Vignola's architectural treatise in the Colegio de Arquitectos de Valencia are analyzed here. The first drawing is a preliminary study for the altarpiece of the Immaculate Conception in the Parrochial Church of El Pedroso (Seville. The second drawing, also a preliminary idea, is for the lost altarpiece of the Dominican monastery of Portacelli in Seville, from which only the figure of St Dominic of Guzman flagellating himself has survived (Museo de Bellas Artes de Sevilla. The third is the model for the type of altarpiece-tabernacle used by Montañés in the Convent of Santa Clara (Seville. The author also points out the origin of certain elements of Montañés's designs in the prints of Vignola's treatise.

    Presentamos un análisis de tres de los dibujos de retablos que se conservan en el ejemplar del Vignola del Colegio de Arquitectos de Valencia y que pertenecen al escultor sevillano Juan Martínez Montañés. El primero de ellos es preparatorio para el retablo de la Inmaculada de la iglesia parroquial del Pedroso (Sevilla, conservado in situ actualmente. El segundo es para el perdido Retablo de los dominicos de Portacoeli de Sevilla, del que se conserva el Santo Domingo de Guzman azotándose en el Museo de Bellas Artes de Sevilla, y el tercero es modelo para la tipología del Montañés del Retablo-Tabernáculo en la iglesia del convento de Santa Clara de Sevilla, estudiándose además el origen de algunos elementos de Montañés en los propios grabados del libro de Vignola.

  13. Effects of singing classes on pulmonary function and quality of life of COPD patients

    Directory of Open Access Journals (Sweden)

    Amanda Gimenes Bonilha

    2008-12-01

    Full Text Available Amanda Gimenes Bonilha1, Fernanda Onofre2, Maria Lucia Vieira1, Maria Yuka Almeida Prado2, José Antônio Baddini Martinez11Internal Medicine Department, Medical School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil; 2Music Department, School of Arts and Communications, University of São Paulo, Ribeirão Preto, São Paulo, Brazil Trial registered at ClinicalTrials.gov: NCT 00500526Abstract: This study aimed to investigate the effects of weekly singings classes on pulmonary function parameters and quality of life (QoL of COPD patients. Forty-three patients were randomized to weekly classes of singing practice, or handcraft work. They performed spirometry and completed maximal respiratory pressure measurements, evaluations of dyspnea, and the Saint George’s Respiratory Questionnaire, before and after 24 training classes. A functional evaluation, immediately after 10 minutes of singing practice, was also performed at the end of the study. Fifteen subjects completed the study in each group. In comparison to controls the singing group exhibited transitory elevations on the dyspnea Borg scale (p = 0.02, and inspiratory capacity (p = 0.01, and decreases of expiratory reserve volume (p = 0.03, just after a short session of singing. There was a significant difference on changes of maximal expiratory pressures in the comparison between groups at the end of training. While the control group showed deterioration of maximal expiratory pressure, the singing group exhibited a small improvement (p = 0.05. Both groups showed significant improvements of QoL in within group comparisons. We have concluded that singing classes are a well tolerated activity for selected subjects with COPD. Regular practice of singing may improve QoL, and preserve the maximal expiratory pressure of these patients.Keywords: COPD; pulmonary function tests; breathing exercises

  14. Toxicity of Spathodea campanulata P Beauvois (Scrophulariales: Bignoniaceae aqueous extracts against immature stages of Anopheles albimanus (Diptera: Culicidae under laboratory conditions

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    Jose Luis Torres-Estrada

    2010-12-01

    Full Text Available Jose Luis Torres-Estrada1, Julio Cesar Velazquez Gonzalez1, Silvany M Rios Delgado1, María Guadalupe Vazquez-Martinez1, R Patricia Penilla-Navarro1, Americo D Rodriguez11Centro Regional de Investigación en Salud Pública, Instituto Nacional de Salud Pública, Colonia Centro, Tapachula, Chiapas, MéxicoPurpose: To determine the effects of African tulip Spathodea campanulata aqueous extracts on every immature stage of Anopheles albimanus under laboratory conditions.Methods: The extract was obtained making an incision on the apical part of prefloral bulbs, and two sets of dilutions with distilled water were prepared. The first set was used at 50%, 20%, 10%, 5%, and 2.5% concentrations in bioassays to test its effect on egg-hatching inhibition. The second set was used at 10%, 5%, 1%, 0.1%, and 0.01% to test toxicity on larvae and pupae. Also, residual efficacy and lethal time (LT were estimated.Results: The highest inhibition (87.5% recorded for egg hatching was at a 50% concentration. Third and fourth instar larvae and pupae were the most susceptible to 10% and 5% of S. campanulata aqueous extracts, with 98.3%–100% mortality. The residual activity with 10% concentration persisted 7 days, with 100% mortality, and LT for 99% mortality (LT99 was 2.28 hours on third instar larvae, 1.7 hours on fourth instar larvae, and 2.25 hours on pupae.Conclusion: S. campanulata extracts are promising as biolarvicides. Further toxicological and chromatographic studies are encouraged and needed.Keywords: African tulip, botanical insecticides, malaria, mosquitoes

  15. Marble Ageing Characterization by Acoustic Waves

    Science.gov (United States)

    Boudani, Mohamed El; Wilkie-Chancellier, Nicolas; Martinez, Loïc; Hébert, Ronan; Rolland, Olivier; Forst, Sébastien; Vergès-Belmin, Véronique; Serfaty, Stéphane

    In cultural heritage, statue marble characterization by acoustic waves is a well-known non-destructive method. Such investigations through the statues by time of flight method (TOF) point out sound speeds decrease with ageing. However for outdoor stored statues as the ones in the gardens of Chateau de Versailles, ageing affects mainly the surface of the Carrara marble. The present paper proposes an experimental study of the marble acoustic properties variations during accelerated laboratory ageing. The surface degradation of the marble is reproduced in laboratory for 29 mm thick marble samples by using heating/cooling thermal cycles on one face of a marble plate. Acoustic waves are generated by 1 MHz central frequency contact transducers excited by a voltage pulse placed on both sides of the plate. During the ageing and by using ad hoc transducers, the marble samples are characterized in transmission, along their volume by shear, compressional TOF measurements and along their surface by Rayleigh waves measurements. For Rayleigh waves, both TOF by transducers and laser vibrometry methods are used to detect the Rayleigh wave. The transmission measurements point out a deep decrease of the waves speeds in conjunction with a dramatic decrease of the maximum frequency transmitted. The marble acts as a low pass filter whose characteristic frequency cut decreases with ageing. This pattern occurs also for the Rayleigh wave surface measurements. The speed change in conjunction with the bandwidth translation is shown to be correlated to the material de-structuration during ageing. With a similar behavior but reversed in time, the same king of phenomena have been observed trough sol-gel materials during their structuration from liquid to solid state (Martinez, L. et all (2004). "Chirp-Z analysis for sol-gel transition monitoring". Ultrasonics, 42(1), 507-510.). A model is proposed to interpret the acoustical measurements

  16. Phantasmatic Constructions: Language and Humor and the Interrogation of Identity in Contemporary Filipino Comic Plays

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    Maria Rhodora G. Ancheta

    2011-12-01

    Full Text Available This paper examines the ways in which humor operates to interrogate and assert Filipino identity in the face of an ever invasive hyperreal intervention in Philippine contemporary life, in two contemporary comic plays, “Welcome to IntelStar” by Chris Martinez (2005, and “Psychedelia Apocalypsis” by Nicolas Pichay (2007. In the former, a comic monologue foregrounds the “call center phenomenon” in the Philippines. Outsourced service is shown as a maneuver which loosely transplants English-speaking, ‘American-sounding’ workers within a global economic community, and one which now comically depicts these workers, in fact, as culturally mired subjects negotiating their identity constructions within their everyday lives. “Psychedelia Apocalypsis” is a farcical depiction of an American film crew’s apparently innocent entry into the Philippine highlands to shoot the Francis Ford Coppola film Apocalypse Now; as a result, they become embroiled in the intersections of Filipino history, current Philippine internal conflicts, and Philippine political feuds, thus highlighting the matrix of current Philippine culture and life. In reading these two plays as shifting cultural texts, I seek to examine how the language of humor and the comic strategies used therein (especially citing the role of incongruity theories respond to the creation, or to the evolution of a hyperreal Filipino identity, one that complicates the fixing of a national identity in the face of a culture that has long grappled with this question, given the Philippines’ own colonial and hybrid culture. And while this paper focuses mainly on Filipino texts and problematizes Filipino identity, it is significant to explore the Asian and Third World reverberations of the possibilities and problems of this cultural reengagement and reconsolidation of identity, examined now by way of language and culture.

  17. Sobre la solución de problemas computacionales en ingeniería mediante grafos dicromáticos. Selección de software de apoyo // About solving computational problems by dichromatic graphs in engineering. Selection of supporting software

    Directory of Open Access Journals (Sweden)

    Sergio Marrero-Osorio

    2011-05-01

    Full Text Available El autor realiza una concisa revisión sobre la aplicación de grafos en la resolución de problemas decómputo en ingeniería, enfatizando en un método propuesto por Martínez Escanaverino que utilizagrafos dicromáticos y ha sido usado en el ámbito científico técnico de Cuba. Analiza, basado en seisejemplos, el escaso empleo que se ha dado hasta el momento al software disponible para trazar yeditar los sucesivos grafos durante el proceso de resolución; estudiando y evaluando un grupo de 18editores de grafos por sus aptitudes para aplicar el mencionado método. Finalmente se recomiendauno de ellos para su uso futuro y se confirma la conveniencia de su empleo a través de unacomparación.Palabras claves: análisis estructural, resolución de problemas, algoritmos, modelo matemático, grafosdicromáticos, editores de grafos.___________________________________________________________________AbstractAuthor makes a concise review about employment of graphs in solving engineering computationalproblems, emphasizing in one method proposed by Martinez Escanaverino which uses dichromaticgraphs and has been applied in Cuban technical sciences. Analyzes, based in six examples, lack inuse (until this moment of software for graph drawing and edition through problem solving process,studying and evaluating 18 available graph editors and suggesting one of them for future applicationsof mentioned method. Finally, making a comparison, are confirmed advantages of its usage.Key words: structural analysis, problem solving, algorithms, mathematical models, dichromatic graphs,graph editors.

  18. El espejismo nacional-socialista. La relación entre dos catedráticos de Prehistoria, Oswald Menghin y Julio Martínez Santa-Olalla (1935-1952

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    Mederos Martín, Alfredo

    2014-12-01

    Full Text Available Oswald Menghin, Professor of Prehistoric Man at the University of Vienna from 1922-45, supported the unity of Austria with Germany, and a sympathizer about the NSDAP ideas on the need to avoid racial mixing between Aryans and Jews. During his time as Professor at the University of Fouad in Cairo from 1930-33 he came into contact with Hermann Junker. This radicalized Menghin’s views and, as a result, he wrote his book, Spirit and Blood. The Basic Principles of Race, Language, Culture and Nation. His time as Rector of the University of Viena from 1936 to 1937 catapulted him into politics: he was a board member of the Austrian fascist party, Vaterländische Front from 1936 to 1937 and was appointed Minister of Education between March and May 1938, just after Hitler’s invasion of Austria. As Minister, he applied for membership in the NSDAP, but because his prior membership in secret Catholic organizations, it was not accepted until June 1940. Menghin was in contact with Martinez Santa-Olalla, after the celebration of the Jubilee of the Institute for Cultural Morphology at Frankfurt in June and July 1938. After Almagro Basch’s research period in Germany and Austria in January and February 1942 and his own visit to Barcelona in June 1942, however, Menghin chose to distance from Martinez Santa-Olalla, not visiting Madrid, cutting the epistolary relationship and reporting negatively about him to the SS-Ahnenerbe. After being imprisoned in two American concentration camps between May 1945 and February 1947, Menghin fled to Argentina in 1948, followed shortly afterwards by his wife and daughter. In Argentina Menghin was supported by Jose Imbelloni, director of the Ethnographic Museum at the University of Buenos Aires since 1947, who hired him as a researcher without teaching. He also received support from Martinez Santa-Olalla through the Spanish Ambassador, Jose Maria de Areilza, and from the Professor of History at the University of Buenos Aires

  19. Neuropsychological effects and attitudes in patients following electroconvulsive therapy

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    Miriam Feliu

    2008-06-01

    Full Text Available Miriam Feliu1,2, Christopher L Edwards1,2,3, Shiv Sudhakar4, Camela McDougald1, Renee Raynor5, Stephanie Johnson6, Goldie Byrd7, Keith Whitfield8, Charles Jonassaint8, Heather Romero1, Lekisha Edwards1, Chante’ Wellington1, LaBarron K Hill9, James Sollers, III9, Patrick E Logue11Department of Psychiatry and Behavioral Sciences; 2Duke Pain and Palliative Care Center; 3Department of Medicine, Division of Hematology; 4Drexel University Medical School; 5Brain Tumor Center, Duke University Medical Center, Durham, NC, USA; 6Science Directorate, American Psychological Association; 7Department of Biology, North Carolina A&T State University; 8Department of Psychology, Duke University; 9Department of Psychology, The Ohio State UniversityAbstract: The current study examined the effects of electroconvulsive therapy (ECT on neuropsychological test performance. Forty-six patients completed brief neuropsychological and psychological testing before and after receiving ECT for the treatment of recalcitrant and severe depression. Neuropsychological testing consisted of the Levin Selective Reminding Test (Levin and Wechsler Memory Scale-Revised Edition (WMS-R. Self-report measures included the Beck Depression Inventory (BDI, the Short-Term Memory Questionnaire (STMQ, and several other measures of emotional functioning and patient attitudes toward ECT. The mean number of days between pre-ECT and post-ECT testing was 24. T-test revealed a significant decrease in subjective ratings of depression as rated by the BDI, t(45 = 9.82, P < 0.0001 (Pre-BDI = 27.9 ± 20.2; post-BDI = 13.5 ± 9.7. Objective ratings of memory appeared impaired following treatment, and patients’ self-report measures of memory confirmed this decline. More specifically, repeated measures MANOVA [Wilks Lambda F(11,30 = 4.3, p < 0.001] indicated significant decreases for measures of immediate recognition memory (p < 0.005, long-term storage (p < 0.05, delayed prose passage recall (p < 0

  20. Book Reviews

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    Redactie KITLV

    2008-12-01

    Britain (Paget Henry Grant Farred; What?s My Name? Black Vernacular Intellectuals (Bill Schwarz Alma Guillermoprieto; Dancing with Cuba: A Memoir of the Revolution (Jane Desmond Amílcar Antonio Barreto; Vieques, the Navy, and Puerto Rican Politics (Juan A. Giusti John Jansen van Galen; De toekomst van het Koninkrijk: Over de dekolonisatie van de Nederlandse Antillen (Rosemarijn Hoefte Miriam Sluis; De Antillen bestaan niet: De nadagen van een fictief land (Rosemarijn Hoefte Mies van Niekerk; Premigration Legacies and Immigrant Social Mobility: The Afro-Surinamese and Indo-Surinamese in the Netherlands (Livio Sansone Dagmar Barnouw; Naipaul?s Strangers (Keith Alan Sprouse Helen Hayward; The Enigma of V.S. Naipaul (Keith Alan Sprouse Evelyn O'Callaghan; Women Writing the West Indies, 1804-1939: “A Hot Place, Belonging to Us.” (Sue N. Greene Dawn F. Stinchcomb; The Development of Literary Blackness in the Dominican Republic. (James J. Davis Bijdragen in: New West Indian Guide / Nieuwe West-Indische Gids vol. 79, no. 3 & 4 (2005

  1. Perspectives of patients on factors relating to adherence to post-acute coronary syndrome medical regimens

    Directory of Open Access Journals (Sweden)

    Lambert-Kerzner A

    2015-07-01

    Full Text Available Anne Lambert-Kerzner,1,2 Edward P Havranek,2,3 Mary E Plomondon,1,2 Katherine M Fagan,1 Marina S McCreight,1 Kelty B Fehling,1 David J Williams,2 Alison B Hamilton,4 Karen Albright,2 Patrick J Blatchford,2 Renee Mihalko-Corbitt,5 Chris L Bryson,6 Hayden B Bosworth,7 Miriam A Kirshner,7 Eric J Del Giacco,5 P Michael Ho1,2 1Department of Cardiology, Veterans Health Administration (VA Eastern Colorado Health Care System, Denver, CO, 2School of Public Health or School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO, 3Cardiology, Denver Health Medical Center, Denver, CO, 4Health Services Research, Veterans Health Administration (VA Greater Los Angeles Healthcare System, Los Angeles, CA, 5Internal Medicine, John L. McClellan Memorial Veterans Hospital, Little Rock, AR, 6Health Services Research, Veterans Health Administration (VA Puget Sound Health Care System, Seattle, WA, 7Health Services Research, Durham Veterans Affairs Medical Center, Durham, NC, USA Purpose: Poor adherence to cardioprotective medications after acute coronary syndrome (ACS hospitalization is associated with increased risk of rehospitalization and mortality. Clinical trials of multifaceted interventions have improved medication adherence with varying results. Patients’ perspectives on interventions could help researchers interpret inconsistent outcomes. Identifying factors that patients believe would improve adherence might inform the design of future interventions and make them more parsimonious and sustainable. The objective of this study was to obtain patients’ perspectives on adherence to medical regimens after experiencing an ACS event and their participation in a medication adherence randomized control trial following their hospitalization. Patients and methods: Sixty-four in-depth interviews were conducted with ACS patients who participated in an efficacious, multifaceted, medication adherence randomized control trial. Interview transcripts were

  2. Proceedings of the 25th Himalaya-Karakoram-Tibet Workshop

    Science.gov (United States)

    Leech, Mary L.; Klemperer, Simon L.; Mooney, Walter D.

    2010-01-01

    how NSF can best support the evolving need for interdisciplinary investigations. This workshop also has clear societal relevance. Recent earthquakes have brought international attention to active tectonics and earthquake hazards in the HKT region. Prominent examples include the Mw 7.8 Kokoxili (Qinghai, China) earthquake of 2001, the Mw 7.6 Kashmir (Pakistan) earthquake of 2005, the Mw 7.9 Wenchuan (Sichuan, China) earthquake of 2008, and this year the Mw 6.9 Yushu (Qinghai, China) earthquake. Geological and geophysical field work conducted both before these earthquakes, as well as in response to them, has helped to define the active faults and regional tectonics in the HKT region. The research presented at this workshop provides the framework necessary for improved seismic hazard assessments in this region. The organizers gratefully acknowledge the support of NSF's Continental Dynamics Program and its Office of International Science and Engineering, through award EAR-0965796. We thank San Francisco State University's Sheldon Axler, Dean of the College of Science and Engineering, and Toby Garfield, Director of the Romberg Tiburon Center, for use of their conference facilities; and the Department of Geosciences, particularly Deb Shulman and Miriam Knof, for administrative support. The California Academy of Sciences generously hosted a reception for visiting delegates, and Brad Ritts (Chevron Exploration Technology Company), Todd Greene (California State University, Chico) and John Shervais (Utah State University) together co-led the pre-conference field trip. Technical editing of this volume was led by Roxanne Renedo (U.S. Geological Survey) with assistance from Margaret Milia (Stanford University). We are grateful to the U.S. Geological Survey (USGS) Earthquake Hazards Program and the USGS Menlo Park (California) Publishing Service Center for making this online report possible.

  3. New Seeds are Resistant to Wheat Stem Rust (Ug99) Multinational Programme Supported by FAO and IAEA

    International Nuclear Information System (INIS)

    2013-01-01

    working together we can overcome the challenges we face', said FAO Director-General Jose Graziano da Silva. The rust-resistant wheat varieties were developed with the support of an IAEA Technical Cooperation project, Responding to the Transboundary Threat of Wheat Black Stem Rust (Ug99), which involved more than 20 nations and international organizations. The varieties were developed using a nuclear technique for crop improvement known as mutation breeding. By exposing seeds, or plant tissue, to radiation, scientists accelerate the natural process of mutation, and then breeders are able to select and develop new varieties. In 2009, Miriam Kinyua, a Kenyan plant breeder, sent 10 kilograms of five varieties of wheat seed to the FAO/IAEA laboratories in Seibersdorf, south of Vienna, where they were irradiated for mutation breeding. These seeds were returned to Kenya where they were planted in a hot spot for the disease for screening and selection. Kinyua and her colleagues at the University of Eldoret's Biotechnology Department identified eight lines resistant to Ug99. Four of these lines were submitted to Kenyan national performance trials, and two were officially approved as varieties by the national committee of the Ministry of Agriculture. About six tonnes of seeds of the new varieties will be made available this month for the next planting season in Kenya. (IAEA)

  4. Tweet for Behavior Change: Using Social Media for the Dissemination of Public Health Messages.

    Science.gov (United States)

    Gough, Aisling; Hunter, Ruth F; Ajao, Oluwaseun; Jurek, Anna; McKeown, Gary; Hong, Jun; Barrett, Eimear; Ferguson, Marbeth; McElwee, Gerry; McCarthy, Miriam; Kee, Frank

    2017-03-23

    common form of cancer (preintervention: 28.4% [95/335] vs postintervention: 39.3% [168/428] answered "True") and that melanoma is most serious (49.1% [165/336] vs 55.5% [238/429]). The results also show improved attitudes toward ultraviolet (UV) exposure and skin cancer with a reduction in agreement that respondents "like to tan" (60.5% [202/334] vs 55.6% [238/428]). Social media-disseminated public health messages reached more than 23% of the Northern Ireland population. A Web-based survey suggested that the campaign might have contributed to improved knowledge and attitudes toward skin cancer among the target population. Findings suggested that shocking and humorous messages generated greatest impressions and engagement, but information-based messages were likely to be shared most. The extent of behavioral change as a result of the campaign remains to be explored, however, the change of attitudes and knowledge is promising. Social media is an inexpensive, effective method for delivering public health messages. However, existing and traditional process evaluation methods may not be suitable for social media. ©Aisling Gough, Ruth F Hunter, Oluwaseun Ajao, Anna Jurek, Gary McKeown, Jun Hong, Eimear Barrett, Marbeth Ferguson, Gerry McElwee, Miriam McCarthy, Frank Kee. Originally published in JMIR Public Health and Surveillance (http://publichealth.jmir.org), 23.03.2017.

  5. Benefits and risks of weight-loss treatment for older, obese women

    Directory of Open Access Journals (Sweden)

    Rossen LM

    2013-02-01

    Full Text Available Lauren M Rossen,1,2 Vanessa A Milsom,1,3 Kathryn R Middleton,1,4 Michael J Daniels,5,6 Michael G Perri1,71Department of Clinical and Health Psychology, University of Florida, Gainesville, FL, USA; 2National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD, USA; 3Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA; 4Weight Control and Diabetes Research Center, Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University and The Miriam Hospital, Providence, RI, USA; 5Department of Statistics, University of Florida, Gainesville, FL, USA; 6Division of Statistics and Scientific Computation, University of Texas at Austin, Austin, TX, USA; 7College of Public Health and Health Professions, University of Florida, Gainesville, FL, USABackground: A key issue in the treatment of obesity in older adults is whether the health benefits of weight loss outweigh the potential risks with respect to musculoskeletal injury.Objective: To compare change in weight, improvements in metabolic risk factors, and reported musculoskeletal adverse events in middle-aged (50–59 years and older (65–74 years, obese women.Materials and methods: Participants completed an initial 6-month lifestyle intervention for weight loss, comprised of weekly group sessions, followed by 12 months of extended care with biweekly contacts. Weight and fasting blood samples were assessed at baseline, month 6, and month 18; data regarding adverse events were collected throughout the duration of the study.Results: Both middle-aged (n = 162 and older (n = 56 women achieved significant weight reductions from baseline to month 6 (10.1 ± 0.68 kg and 9.3 ± 0.76 kg, respectively and maintained a large proportion of their losses at month 18 (7.6 ± 0.87 kg and 7.6 ± 1.3 kg, respectively; there were no significant differences between the two groups with respect to weight change. Older women further

  6. Editorial das organizadoras do VI ENANCIB

    Directory of Open Access Journals (Sweden)

    Ligia Maria Arruda Café

    2006-07-01

    , realizado em Florianópolis de 28 a 30 de novembro de 2005, selecionados em cada Grupo de Trabalho como os mais significativos de sua área. Destacamos do conjunto dos artigos apresentados aspectos relacionados às novas abordagens e métodos de trabalho, ao deslocamento do enfoque dos espaços tradicionais para novos ambientes, ao uso intensivo das tecnologias e sua relação com o ambiente em que estão inseridas, às aplicações de pesquisa em contextos específicos como, por exemplo, as agências de fomento, as bibliotecas digitais, o meio empresarial e as redes sociais, entre outros. Florianópolis, fevereiro de 2006. Ligia Café Miriam Vieira da Cunha Presidente da Comissão Científica Presidente do VI ENANCIB

  7. Obituary: Walter Alexander Feibelman, 1930-2004

    Science.gov (United States)

    Oergerle, William

    2005-12-01

    , physics, telescopes, and railroading. His awards included a special achievement award from NASA in 1986, a Presidential Certificate of Recognition on National Immigrants Day in 1987, and a NASA Certificate of Outstanding Performance in 1990. Walter was fascinated with steam locomotives. He documented in photographs the end of the steam era in western Pennsylvania, and published an illustrated study of those giant locomotives in a book, "Rails to Pittsburgh", in 1979. From the New York Central Railroad, he purchased the shop blueprints of its famous "Niagara" locomotive. He scaled those plans and machined more than 1,100 individual parts from brass, which he assembled over several years into a 31-inch model of a Niagara that sat on O-gauge track. He loved classical music, and made an extensive collection of videos of famous performances, which he showed in well-attended weekly gatherings at Riderwood. He presented his 200th program to listeners the night before he died. He was preceded in death by his wife, Lola King Feibelman. Survivors include a sister, Miriam Feibelman of Jerusalem.

  8. Response of surface and groundwater on meteorological drought in Topla River catchment, Slovakia

    Science.gov (United States)

    Fendekova, Miriam; Fendek, Marian; Vrablikova, Dana; Blaskovicova, Lotta; Slivova, Valeria; Horvat, Oliver

    2016-04-01

    upper gauging station in Bardejov lasts usually longer than in Hanusovce nad Toplou station being located downstream. Higher number of short-term droughts was estimated for groundwater head in one monitoring well with the smallest depth of groundwater head below the surface. In this case, the influence of evapotranspiration could be the reason. More long-term droughts were estimated by TLM method for groundwater heads in other seven monitoring wells. Those droughts lasted for tens of weeks since summer until the spring of the next year. No regularity in temporal groundwater head drought propagation downstream the Topla River was discovered. However, results of the cluster analysis showed some common features of long-term drought periods (more than 100 days) occurrence for two groups of wells. Different hydrogeological conditions in two evaluated wells were also reflected in drought periods number and severity. The research was financially supported by APVV-0089-12 project (principal investigator Miriam Fendekova).

  9. Anticonvulsant effects of isomeric nonimidazole histamine H3 receptor antagonists

    Directory of Open Access Journals (Sweden)

    Sadek B

    2016-11-01

    Full Text Available Bassem Sadek,1 Ali Saad,1 Johannes Stephan Schwed,2,3 Lilia Weizel,2 Miriam Walter,2 Holger Stark2,3 1Department of Pharmacology and Therapeutics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates; 2Biocenter, Institute of Pharmaceutical Chemistry, Goethe University, Frankfurt, Germany; 3Department of Pharmaceutical and Medicinal Chemistry, Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine University, Düsseldorf, Germany Abstract: Phenytoin (PHT, valproic acid, and modern antiepileptic drugs (AEDs, eg, remacemide, loreclezole, and safinamide, are only effective within a maximum of 70%–80% of epileptic patients, and in many cases the clinical use of AEDs is restricted by their side effects. Therefore, a continuous need remains to discover innovative chemical entities for the development of active and safer AEDs. Ligands targeting central histamine H3 receptors (H3Rs for epilepsy might be a promising therapeutic approach. To determine the potential of H3Rs ligands as new AEDs, we recently reported that no anticonvulsant effects were observed for the (S-2-(4-(3-(piperidin-1-ylpropoxybenzylaminopropanamide (1. In continuation of our research, we asked whether anticonvulsant differences in activities will be observed for its R-enantiomer, namely, (R-2-(4-(3-(piperidin-1-ylpropoxybenzylaminopropaneamide (2 and analogs thereof, in maximum electroshock (MES-, pentylenetetrazole (PTZ-, and strychnine (STR-induced convulsion models in rats having PHT and valproic acid (VPA as reference AEDs. Unlike the S-enantiomer (1, the results show that animals pretreated intraperitoneally (ip with the R-enantiomer 2 (10 mg/kg were moderately protected in MES and STR induced models, whereas proconvulsant effect was observed for the same ligand in PTZ-induced convulsion models. However, animals pretreated with intraperitoneal doses of 5, 10, or 15 mg/kg of structurally bulkier (R-enantiomer (3

  10. Books Noted

    Science.gov (United States)

    Walsh, Edward J.

    1999-10-01

    The Colloidal Domain: Where Physics, Chemistry, Biology, and Technology Meet, 2nd edition D. Fennell Evans and Hakan Wennerstroem. Advances in Interfacial Engineering Series. Wiley-VCH: New York, 1999. xl + 632 pp. ISBN 0-471-24247-0. 89.95. Commercial Nuclear Power: Assuring Safety for the Future Charles B. Ramsey and Mohammed Modarres. Wiley-Interscience: New York, 1998. xxviii + 508 pp. ISBN 0-471-29186-2. 79.95. Advances in Medicinal Chemistry, Vol. 4 Bruce E. Maryanoff and Allen B. Reitz, Eds. JAI Press: Stamford, CT, 1999. ISBN 1-7623-0064-7. 109.50. Advances in Strained and Interesting Organic Molecules, Vol. 7 Brian Halton, Ed. JAI Press: Stamford, CT, 1999. xii + 259 pp. ISBN 0-7623-0530-4. 109.50. Advances in Electron Transfer Chemistry, Vol. 6 Patrick S. Mariano, Ed. JAI Press: Stamford, CT, 1999. x + 171 pp. ISBN 0-7623-0213-5. 109.50. Automating Science and Engineering Laboratories with Visual Basic Mark F. Russo and Martin M. Echols. Wiley-Interscience Series on Laboratory Automation. Wiley-Interscience: New York, 1999. xx + 355 pp. ISBN 0-471-25493-2. 49.95. Plantwide Process Control Kelvin T. Erickson and John L. Hedrick. Wiley Series in Chemical Engineering. Wiley-Interscience: New York, 1999. xii + 547 pp. ISBN 0-471-17835-7. 89.95. Heme Peroxidases H. Brian Dunford. Wiley-VCH: New York, 1999. xiii + 507 pp. ISBN 0-471-24244-6. 195.00. Industrial Ecology: Environmental Chemistry and Hazardous Wastes Stanley E. Manahan. Lewis: Boca Raton, FL, 1999. 318 pp. ISBN 1-56670-381-6. 69.95. Reviews in Computational Chemistry, Vol. 13 Kenny B. Lipkowitz and Donald B. Boyd. Wiley-VCH: New York, 1999. xxxiii + 426 pp. ISBN 0-471-33135-x. 135.00. Surfaces, Interfaces, and Colloids: Principles and Applications, 2nd edition Drew Myers. Wiley-VCH: New York, 1999. xx + 501 pp. ISBN 0-471-33060-4. 94.95. Onium Ions George A. Olah, Kenneth K. Laali, Qi Wang, and G. K. Surya Prakash. Wiley-Interscience: New York, 1998. xv + 509 pp. ISBN 0-471-14877-6. 110

  11. Vertical Jump and Leg Power Normative Data for Colombian Schoolchildren Aged 9-17.9 Years: The FUPRECOL Study.

    Science.gov (United States)

    Ramírez-Vélez, Robinson; Correa-Bautista, Jorge E; Lobelo, Felipe; Cadore, Eduardo L; Alonso-Martinez, Alicia M; Izquierdo, Mikel

    2017-04-01

    Ramírez-Vélez, R, Correa-Bautista, JE, Lobelo, F, Cadore, EL, Alonso-Martinez, AM, and Izquierdo, M. Vertical jump and leg power normative data for Colombian schoolchildren aged 9-17.9 years: the FUPRECOL study. J Strength Cond Res 31(4): 990-998, 2017-The aims of the present study were to generate normative vertical jump height and predicted peak power (Ppeak) data for 9- to 17.9-year-olds and to investigate between-sex and age group differences in these measures. This was a cross-sectional study of 7,614 healthy schoolchildren (boys n = 3,258 and girls n = 4,356, mean [SD] age 12.8 [2.3] years). Each participant performed 2 countermovement jumps; jump height was calculated using a Takei 5414 Jump-DF Digital Vertical (Takei Scientific Instruments Co., Ltd.). The highest jump was used for analysis and in the calculation of predicted Ppeak. Centile smoothed curves, percentiles, and tables for the 3rd, 10th, 25th, 50th, 75th, 90th, and 97th percentiles were calculated using Cole's LMS (L [curve Box-Cox], M [curve median], and S [curve coefficient of variation]) method. The 2-way analysis of variance tests showed that maximum jump height (in centimeters) and predicted Ppeak (in watts) were higher in boys than in girls (p jump height and Ppeak in all ages. In boys, the maximum jump height and predicted Ppeak 50th percentile ranged from 24.0 to 38.0 cm and from 845.5 to 3061.6 W, respectively. In girls, the 50th percentile for jump height ranged from 22.3 to 27.0 cm, and the predicted Ppeak was 710.1-2036.4 W. For girls, jump height increased yearly from 9 to 17.9 years old. Our results provide, for the first time, sex- and age-specific vertical jump height and predicted Ppeak reference standards for Colombian schoolchildren aged 9-17.9 years.

  12. Evaluating Patient Empowerment in Association With eHealth Technology: Scoping Review.

    Science.gov (United States)

    Risling, Tracie; Martinez, Juan; Young, Jeremy; Thorp-Froslie, Nancy

    2017-09-29

    empirical publications, only four were found to have used specific patient empowerment measures with significant variety in their identified conceptual elements. There is a persistent lack of conceptual clarity in patient empowerment research, and this has extended to study within the eHealth context. The interchangeable use or conflation of terms such as patient empowerment, engagement, and activation, has further complicated the advancement of distinct conceptual measures. To more strongly align changes in patient empowerment with supportive eHealth solutions, the challenges of achieving a consensus on how best to operationalize and measure patient empowerment must be met. ©Tracie Risling, Juan Martinez, Jeremy Young, Nancy Thorp-Froslie. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 29.09.2017.

  13. Redefining face contour with a novel anti-aging cosmetic product: an open-label, prospective clinical study

    Directory of Open Access Journals (Sweden)

    Garre A

    2017-11-01

    Full Text Available Aurora Garre,1 Gemma Martinez-Masana,1 Jaime Piquero-Casals,2 Corinne Granger1 1Innovation and Development, ISDIN S.A., Barcelona, Spain; 2Dermik Clinic, Barcelona, Spain Background: Skin aging is accelerated by multiple extrinsic factors: ultraviolet radiation, smoking and pollution increase oxidative activity, damaging cellular and extracellular components such as DNA, proteins, and lipids. With age, collagen and hyaluronic acid levels decline, resulting in loss of elasticity and moisture of the skin. Over time this damage leads to characteristic signs that make the skin look older: altered facial contour, sagging skin, wrinkles, and an uneven complexion. This study evaluated the anti-aging effects of a new facial cream formulated with carnosine, Alteromonas ferment extract, crosspolymer hyaluronic acid, and a tripeptide. Methods: An open-label intra-individual study to assess the anti-aging efficacy of the investigational product in 33 women aged 45 to 65 years. The product was applied twice daily for 56 days. Facial contour and skin deformation, elasticity, hydration, and complexion were measured with specialized equipment at baseline and days 28 and 56. Additionally, subjects completed questionnaires at days 28 and 56 on the perceived efficacy and cosmetic characteristics of the product. Results: After 56 days of use of the investigational product, a redefining effect was observed, with a significant decrease in sagging jawline (7%. Skin was significantly more hydrated (12%, firmer (29%, and more elastic (20% (P<0.001 for all. On complexion assessment, skin texture (a measure of skin smoothness and spots (brown and red skin lesions also improved significantly (12% and 6% decrease, respectively. In the subjective self-evaluation, the majority of subjects reported that the skin was visibly tightened and more elastic, flexible, and moisturized (91%, 88%, 91%, and 90%, respectively. The product was well tolerated with no adverse events reported

  14. Reconstructing the Mineralogy and Bioavailability of Dust-Borne Iron Deposited to the Southern Ocean through the Last Glacial Cycle

    Science.gov (United States)

    Shoenfelt, E. M.; Winckler, G.; Lamy, F.; Bostick, B. C.

    2017-12-01

    and Fe deposited to the Southern Ocean during glacial periods, glacial Fe was also more bioavailable due to the importance of glacial activity to high latitude dust formation. [1] A. Martinez-Garcia et al., Science 343 (2014). [2] A. W. Schroth et al., Nat. Geosci. 2 (2009). [3] E. M. Shoenfelt et al., Sci. Adv. 3(6), DOI:10.1126/sciadv.1700314 (2017).

  15. Pharmacological and toxicological effects of co-exposure of human gingival fibroblasts to silver nanoparticles and sodium fluoride

    Directory of Open Access Journals (Sweden)

    Inkielewicz-Stepniak I

    2014-04-01

    Full Text Available Iwona Inkielewicz-Stepniak,1,* Maria Jose Santos-Martinez,2–4,* Carlos Medina,2,4 Marek W Radomski2,41Department of Medicinal Chemistry, Medical University Gdansk, Debinki, Poland; 2The School of Pharmacy and Pharmaceutical Sciences, Panoz Institute, Trinity College Dublin, Dublin, Ireland; 3School of Medicine, Trinity College Dublin, Dublin, Ireland; 4Trinity Biomedical Sciences Institute, Trinity College, Dublin, Ireland*These authors contributed equally to this workBackground: Silver nanoparticles (AgNPs and fluoride (F are pharmacological agents widely used in oral medicine and dental practice due to their anti-microbial/anti-cavity properties. However, risks associated with the co-exposure of local cells and tissues to these xenobiotics are not clear. Therefore, we have evaluated the effects of AgNPs and F co-exposure on human gingival fibroblast cells.Methods: Human gingival fibroblast cells (CRL-2014 were exposed to AgNPs and/or F at different concentrations for up to 24 hours. Cellular uptake of AgNPs was examined by transmission electron microscopy. Downstream inflammatory effects and oxidative stress were measured by real-time quantitative polymerase chain reaction (PCR and reactive oxygen species (ROS generation. Cytotoxicity and apoptosis were measured by 3-(4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide (MTT assay and real-time quantitative PCR and flow cytometry, respectively. Finally, the involvement of mitogen-activated protein kinases (MAPK was studied using Western blot.Results: We found that AgNPs penetrated the cell membrane and localized inside the mitochondria. Co-incubation experiments resulted in increased oxidative stress, inflammation, and apoptosis. In addition, we found that co-exposure to both xenobiotics phosphorylated MAPK, particularly p42/44 MAPK.Conclusion: A combined exposure of human fibroblasts to AgNPs and F results in increased cellular damage. Further studies are needed in order to evaluate

  16. Effect of Severe Winter Cold on the Photosynthetic Potentials of Three Co-occurring Evergreen Woody Species in a Mediterranean Forest, Catalonia (Spain)

    Science.gov (United States)

    Sperlich, Dominik; Gracia, Carlos; Peñuelas, Josep; Sabaté, Santi

    2013-04-01

    Evergreen tree species in the Mediterranean region have to cope with a wide range of environmental stress conditions from summer drought to winter cold. The winter period can lead to photoinhibition due to a combination of high solar irradiances and chilling temperatures which can reduce the light saturation point. However, Mediterranean winter mildness can lead periodically to favourable environmental conditions above the threshold for positive carbon balance benefitting evergreen woody species in contrast to winter deciduous species. The advantage of being able to photosynthesis all year round with a significant fraction in the winter month is compensating for the lower photosynthetic potentials during spring and summer in comparison to deciduous species. In this work, we investigated the physiological behaviour of three evergreen tree species (Quercus ilex, Pinus halepensis, Arbutus undeo) co-occurring in a natural and mature Mediterranean forest after a period of mild winter conditions and their response to a sudden period of intense cold weather. Therefore, we examined in each period the photosynthetic potentials by estimating the maximum carboxylation rate (Vcmax) and the maximum electron transport rate (Jmax) through gas exchange measurements. The results indicate that all species exhibited extraordinary high photosynthetic potentials during the first period of measurement as a response to the mild conditions. However, the sudden cold period affected negatively the photosynthetic potentials of Quercus ilex and A. unedo with reduction ranging between 37 to 45 %, whereas they were observed to be only insignificantly reduced in Pinus halepensis. Our results can be explained by previous classifications into photoinhibition-avoiding (P. halpensis) and photoinhibition-tolerant (Q. ilex, A. undeo) species on the basis of their susceptibility to dynamic photoinhibition (Martinez Ferri 2000). Photoinhibition tolerant species are characterised with a more dynamic

  17. Problematizing a general physics class: Understanding student engagement

    Science.gov (United States)

    Spaid, Mark Randall

    This research paper describes the problems in democratizing a high school physics course and the disparate engagement students during class activities that promote scientific inquiry. Results from the Learning Orientation Questionnaire (Martinez, 2000) guide the participant observations and semi-formal interviews. Approximately 60% of the participants self-report a "resistant" or "conforming" approach to learning science; they expect to receive science knowledge from the teacher, and their engagement is influenced by affective and conative factors. These surface learners exhibit second order thinking (Kegan, 1994), do not understand abstract science concepts, and learn best from structured inquiry. To sustain engagement, conforming learners require motivational and instructional discourse from their teacher and peers. Resisting learners do not value learning and do not engage in most science class activities. The "performing" learners are able to deal with abstractions and can see relationships between lessons and activities, but they do not usually self-reflect or think critically (they are between Kegan's second order and third order thinking). They may select a deeper learning strategy if they value the knowledge for a future goal; however, they are oriented toward assessment and rely on the science teacher as an authority. They are influenced by affective and conative factors during structured and guided inquiry-based teaching, and benefit from motivational discourse and sustain engagement if they are interested in the topic. The transforming learners are more independent, self-assessing and self-directed. These students are third order thinkers (Kegan, 1994) who hold a sophisticated epistemology that includes critical thinking and reflection. These students select deep learning strategies without regard to affective and conative factors. They value instructional discourse from the teacher, but prefer less structured inquiry activities. Although specific

  18. The Free Jet Microwave Spectrum of 2-PHENYLETHYLAMINE-WATER

    Science.gov (United States)

    Melandri, Sonia; Giuliano, B. Michela; Maris, Assimo; Caminati, Walther

    2009-06-01

    spectrum and we are hoping to assign them to a second conformational species of PEA-W. (a) S. J. Martinez, J. C. Alfano and D. H. Levy J. Mol. Struct. 158 82 1993. (b)P. D. Godfrey,L. D. Hatherley and R. D. Brown J. Am. Chem. Soc. 117 8204 1995. (c)S. Sun and E. R. Bernstein J. Am. Chem. Soc. 118 5086 1996. (d) J. A. Dickinson, M. R. Hockridge, R. T. Kroemer, E. G. Robertson, J. P. Simons, J. McCombie and M. Walker J. Am. Chem. Soc. 120 2622 1998. (e) J. C. Lopez, V. Cortijo, S. Blanco and J. Alonso PCCP 9 4521 2007.

  19. Antiaging effects of a novel facial serum containing L-ascorbic acid, proteoglycans, and proteoglycan-stimulating tripeptide: ex vivo skin explant studies and in vivo clinical studies in women

    Directory of Open Access Journals (Sweden)

    Garre A

    2018-05-01

    Full Text Available Aurora Garre,1 Mridvika Narda,1 Palmira Valderas-Martinez,1 Jaime Piquero,2 Corinne Granger1 1Innovation and Development, ISDIN SA, Barcelona, Spain; 2Dermik Clinic, Barcelona, Spain Background: With age, decreasing dermal levels of proteoglycans, collagen, and elastin lead to the appearance of aged skin. Oxidation, largely driven by environmental factors, plays a central role.Aim: The aim of this study was to assess the antiaging efficacy of a topical serum containing l-ascorbic acid, soluble proteoglycans, low molecular weight hyaluronic acid, and a tripeptide in ex vivo and in vivo clinical studies.Methods: Photoaging and photo-oxidative damage were induced in human skin explants by artificial solar radiation. Markers of oxidative stress – reactive oxygen species (ROS, total glutathione (GSH, and cyclobutane pyrimidine dimers (CPDs – were measured in serum-treated explants and untreated controls. Chronological aging was simulated using hydrocortisone. In both ex vivo studies, collagen, elastin, and proteoglycans were determined as measures of dermal matrix degradation. In women aged 21–67 years, hydration was measured up to 24 hours after a single application of serum, using Corneometer and hygrometer. Subjects’ perceptions of efficacy and acceptability were assessed via questionnaire after once-daily serum application for 4 weeks. Studies were performed under the supervision of a dermatologist.Results: In the photoaging study, irradiation induced changes in ROS, CPD, GSH, collagen, and elastin levels; these changes were reversed by topical serum application. The serum also protected against hydrocortisone-induced reduction in collagen, elastin, and proteoglycan levels, which were significantly higher in the serum-treated group vs untreated hydrocortisone-control explants. In clinical studies, serum application significantly increased skin moisture for 6 hours. Healthy volunteers perceived the product as efficient in making the

  20. Focusing on outcomes: Making the most of COPD interventions

    Directory of Open Access Journals (Sweden)

    Noreen M Clark

    2008-10-01

    Full Text Available Noreen M Clark1, Julia A Dodge1, Martyn R Partridge2, Fernando J Martinez31Center for Managing Chronic Disease, University of Michigan, Ann Arbor, MI, USA; 2Imperial College of Science, Technology and Medicine, London, England, UK; 3Department of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan, USAAbstract: A number of excellent intervention studies related to clinical and psychosocial aspects of chronic obstructive pulmonary disease (COPD have been undertaken in the recent past. A range of outcomes have been examined including pulmonary function, health care use, quality of life, anxiety and depression, ambulation, exercise capacity, and self-efficacy. The purpose of this narrative review was to a consider clinical, psychosocial, and educational interventions for people living with COPD in light of the health related outcomes that they have produced, b identify the type of interventions most associated with outcomes, c examine work related to COPD interventions as it has evolved regarding theory and models compared to work in asthma, and d explore implications for future COPD research. Studies reviewed comprised large scale comprehensive reviews including randomized clinical trials and meta-analysis as these forms of investigation engender the greatest confidence in clinicians and health care researchers. Extant research suggests that the most significant improvements in COPD health care utilization have been realized from interventions specifically designed to enhance disease management by patients. A range of interventions have produced modest changes in quality of life. Evidence of impact for other outcomes and for a particular type of intervention is not strong. Research in other chronic diseases, particularly asthma, suggests that interventions grounded in learning theory and models of behavior change can consistently produce desired results for patients and clinicians. Use of a model of self-regulation may

  1. Profile of guanfacine extended release and its potential in the treatment of attention-deficit hyperactivity disorder

    Directory of Open Access Journals (Sweden)

    Martinez-Raga J

    2015-05-01

    Full Text Available Jose Martinez-Raga,1,2 Carlos Knecht,3 Raquel de Alvaro4 1Teaching Unit of Psychiatry and Psychological Medicine, University Hospital Doctor Peset, University of Valencia, 2CEU Cardenal Herrera University, 3Área de Salud Mental, Hospital Padre Jofré, Valencia, 4Hospital General, Consorcio Hospitalario Provincial, Castellon, Spain Abstract: The α2-adrenergic receptor agonist guanfacine, in its extended-release formulation (GXR, is the most recent nonstimulant medication approved in several countries for the treatment of attention-deficit hyperactivity disorder (ADHD as monotherapy and as adjunctive pharmacotherapy to stimulants in children and adolescents. The present paper aims to review comprehensively and critically the pharmacodynamic and pharmacokinetic characteristics and the published evidence on the efficacy and safety profile of GXR in the treatment of ADHD. A comprehensive search of relevant databases (PubMed, Embase, and PsycInfo was conducted to identify studies published in peer-reviewed journals until January 15, 2015. Though the precise mechanism of action of guanfacine in the treatment of ADHD is not fully understood, it is thought to act directly by enhancing noradrenaline functioning via α2A-adrenoceptors in the prefrontal cortex. Weight-adjusted doses should be used, with a dosing regime on a milligram per kilogram basis, starting at doses in the range 0.05–0.08 mg/kg/day, up to 0.12 mg/kg/day. As evidenced in short-term randomized controlled trials and in long-term open-label extension studies, GXR has been shown to be effective as monotherapy in the treatment of ADHD. Furthermore, GXR has also been found to be effective as adjunctive therapy to stimulant medications in patients with suboptimal responses to stimulants. Many of the adverse reactions associated with GXR, particularly sedation-related effects, were dose-related, transient, mild to moderate in severity, and did not interfere with attention or overall

  2. Pharmacological interventions for adolescents and adults with ADHD: stimulant and nonstimulant medications and misuse of prescription stimulants

    Directory of Open Access Journals (Sweden)

    Weyandt LL

    2014-09-01

    Full Text Available Lisa L Weyandt, Danielle R Oster, Marisa E Marraccini, Bergljot Gyda Gudmundsdottir, Bailey A Munro, Brynheld Martinez Zavras, Ben Kuhar Department of Psychology, University of Rhode Island, Kingston, RI, USA Abstract: Attention-deficit/hyperactivity disorder (ADHD is a neurodevelopmental disorder characterized by symptoms of inattention, hyperactivity, and impulsivity that cause functional impairment. Recent research indicates that symptoms persist into adulthood in the majority of cases, with prevalence estimates of approximately 5% in the school age population and 2.5%–4% in the adult population. Although students with ADHD are at greater risk for academic underachievement and psychosocial problems, increasing numbers of students with ADHD are graduating from high school and pursuing higher education. Stimulant medications are considered the first line of pharmacotherapy for individuals with ADHD, including college students. Although preliminary evidence indicates that prescription stimulants are safe and effective for college students with ADHD when used as prescribed, very few controlled studies have been conducted concerning the efficacy of prescription stimulants with college students. In addition, misuse of prescription stimulants has become a serious problem on college campuses across the US and has been recently documented in other countries as well. The purpose of the present systematic review was to investigate the efficacy of prescription stimulants for adolescents and young adults with ADHD and the nonmedical use and misuse of prescription stimulants. Results revealed that both prostimulant and stimulant medications, including lisdexamfetamine dimesylate, methylphenidate, amphetamines, and mixed-amphetamine salts, are effective at reducing ADHD symptoms in adolescents and adults with ADHD. Findings also suggest that individuals with ADHD may have higher rates of stimulant misuse than individuals without the disorder, and

  3. MPLM On-Orbit Interface Dynamic Flexibility Modal Test

    Science.gov (United States)

    Bookout, Paul S.; Rodriguez, Pedro I.; Tinson, Ian; Fleming, Paolo

    2001-01-01

    Now that the International Space Station (ISS) is being constructed, payload developers have to not only verify the Shuttle-to-payload interface, but also the interfaces their payload will have with the ISS. The Multi Purpose Logistic Module (MPLM) being designed and built by Alenia Spazio in Torino, Italy is one such payload. The MPLM is the primary carrier for the ISS Payload Racks, Re-supply Stowage Racks, and the Resupply Stowage Platforms to re-supply the ISS with food, water, experiments, maintenance equipment and etc. During the development of the MPLM there was no requirement for verification of the on-orbit interfaces with the ISS. When this oversight was discovered, all the dynamic test stands had already been disassembled. A method was needed that would not require an extensive testing stand and could be completed in a short amount of time. The residual flexibility testing technique was chosen. The residual flexibility modal testing method consists of measuring the free-free natural frequencies and mode shapes along with the interface frequency response functions (FRF's). Analytically, the residual flexibility method has been investigated in detail by, MacNeal, Martinez, Carne, and Miller, and Rubin, but has not been implemented extensively for model correlation due to difficulties in data acquisition. In recent years improvement of data acquisition equipment has made possible the implementation of the residual flexibility method as in Admire, Tinker, and Ivey, and Klosterman and Lemon. The residual flexibility modal testing technique is applicable to a structure with distinct points (DOF) of contact with its environment, such as the MPLM-to-Station interface through the Common Berthing Mechanism (CBM). The CBM is bolted to a flange on the forward cone of the MPLM. During the fixed base test (to verify Shuttle interfaces) some data was gathered on the forward cone panels. Even though there was some data on the forward cones, an additional modal test was

  4. Simvastatin modulates gingival cytokine and MMP production in a rat model of ligature-induced periodontitis

    Directory of Open Access Journals (Sweden)

    Mouchrek Júnior JCE

    2017-05-01

    Full Text Available José Carlos Elias Mouchrek Júnior,1 Cristina Gomes Macedo,2 Henrique Ballassini Abdalla,2 Ana Karina Saba,1 Lucas Novaes Teixeira,1 Adriana Quinzeiro e Silva Mouchrek,3 Marcelo Henrique Napimoga,1 Juliana Trindade Clemente-Napimoga,1 Alvaro Henrique Borges,4 Mateus Rodrigues Tonetto,4 Shelon Cristina Souza Pinto,5 Matheus Coelho Bandeca,3 Elizabeth Ferreira Martinez1 1Laboratory of Cell and Molecular Biology, São Leopoldo Mandic Institute and Research Center, Campinas, 2Physiological Sciences, Piracicaba Dental School, University of Campinas, Campinas, São Paulo, 3Department of Dentistry, CEUMA University, São Luis, Maranhão, 4Department of Integrated Dental Science, University of Cuiaba, Cuiabá, Mato Grosso, 5Department of Dentistry, Ponta Grossa State University, Ponta Grossa, Paraná, Brazil Purpose: The aim of this study was to evaluate the effect of simvastatin on the synthesis of cytokines TNF-α and IL-10 and metalloproteinase (MMPs 2 and 9 in a rat model of ligature-induced periodontitis.Materials and methods: Twenty Wistar rats were used, and a cotton ligature was place in a subgingival position encircling the entire cervix of the first molar of the left (ipsilateral side of the mandible. The right (contralateral side of the mandible had no ligature placed and was used as control. After the ligature placement, animals were randomly assigned to two experimental groups (n=10: 1 rats with ligature + vehicle (saline; 10 mL/kg; orally and 2 rats with ligature + simvastatin (25 mg/kg; orally. After 14 days of treatment, the animals were euthanized by anesthetic overdose and the gingival tissue was removed and homogenized in appropriate buffer. MMP-2 and -9 release as well as the IL-10 and TNF-α levels were detected by enzyme-linked immunosorbent assay. Statistical comparison was performed by unpaired Student’s t-test, with p<0.05 representing significance.Results: No differences were observed for TNF-α production between the

  5. Voxel-by-voxel analysis of ECD-brain SPECT can separate penumbra from irreversibly damaged tissue at the acute phase of stroke

    International Nuclear Information System (INIS)

    Darcourt, J.; Migneco, O.; David, O.; Bussiere, F.; Mahagne, M.H.; Dunac, A.; Baron, J.C.

    2002-01-01

    Aim. At the acute phase of ischemic stroke, the target of treatment is still salvageable hypoperfused cerebral tissue; so called penumbra. We tested the possibility of separating on early ECD brain SPECT penumbral voxels (P) from irreversibly damaged damaged tissue (IDT). We used ECD which is not only a perfusion tracer but also a metabolic marker. Materials and methods. We prospectively studied 18 patients who underwent ECD-SPECT within the 12 hours following a first-ever acute middle cerebral artery stroke. Neurological evaluation was performed using the Orgogozo's scale at admission and 3 months later in order to calculate and evolution index (IE%) (Martinez-Vila et al.). SPECT data were obtained using a triple head camera equipped with fan beam collimators one hour after injection of 1000 MBq of 99mTc-ECD. On reconstructed images gray matter voxels were automatically segmented. Contralateral healthy hemisphere was used as reference leading to the identification of 3 cortical voxel types: normal (N-SPECT) above 80%; penumbra (P-SPECT) between 80% and 40% and IDT (IDT-SPECT) below 40%. 10 patients also underwent a T2 weighted 3D MRI study at 3 months. Cortical voxels with hypersignal served as reference for IDT (IDT-MRI) the others were considered normal (N-MRI). SPECT and MRI data were co-registered. Therefore each voxel belonged to one of 6 categories (3 SPECT x 2 MRI). Results. (1) The SPECT thresholds were validated on the MRI subgroup. 99% of the N-SPECT voxels were normal on late MRI. 84% of IDT-SPECT voxels corresponded to IDT-MRI. 89% of P-SPECT voxels were normal on late MRI and 11% corresponded to IDT on late MRI. Other categories of voxels (N-SPECT IDT-MRI and IDT-SPECT N-MRI) represented less than 5%. (2) Percentages of each voxel SPECT type was correlated with the EI% on the entire population (Spearman test). P-SPECT extent correlated with EI% improvement (p<0.001) and IDT-SPECT with EI% worsening (p<0.001). Conclusion. Analysis of ECD cortical

  6. Challenges in modeling unstable two-phase flow experiments in porous micromodels

    Science.gov (United States)

    Meheust, Y.; Ferrari, A.; Jimenez-Martinez, J.; Le Borgne, T.; Lunati, I.

    2014-12-01

    order of magnitude as the pore to pore variability of those widths. [1] A. Ferrari, J. Jimenez-Martinez ,T. Le Borgne , Y. Méheust, and I. Lunati (2014), Challenges in modeling unstable two-phase flow experiments in porous micromodels, submitted.

  7. Validation of Health Behavior and Stages of Change Questionnaire

    Directory of Open Access Journals (Sweden)

    Gonzalez-Ramirez LP

    2017-03-01

    Full Text Available Leivy Patricia Gonzalez-Ramirez,1,2 Jose Maria De la Roca-Chiapas,2 Cecilia Colunga-Rodriguez,3,4 Maria de Lourdes Preciado-Serrano,3 Adrian Daneri-Navarro,5 Francisco Javier Pedroza-Cabrera,6 Reyna Jazmin Martinez-Arriaga1 1Department of Health Sciences, University Centre of Tonala, University of Guadalajara, Guadalajara, 2Department of Psychology, Division of Health Sciences, Campus Leon, University of Guanajuato, Guanajuato, 3Department of Public Health, University Centre for Health Sciences, University of Guadalajara, 4Paediatric Hospital, Western National Medical Centre, Mexican Social Security Institute, 5Departament of Physiology, University Centre for Health Sciences, University of Guadalajara, Guadalajara, 6Department of Psychology, Autonomous University of Aguascalientes, Aguascalientes, Mexico Background: The transtheoretical model (TTM has been widely used to promote healthy behaviors in different groups. However, a questionnaire has not yet been developed to evaluate the health behaviors that medical practitioners often consider in individuals with cancer or at a high risk of developing cancer.Purpose: The aim of this study was to construct and validate the Health Behavior and Stages of Change Questionnaire (HBSCQ, which is based on the TTM and health recommendations related to risk and factors that protect against cancer. Methods: Content validity was conducted in two phases (qualitative and quantitative. Item difficulty index, item discrimination index, and discrimination coefficient were obtained based on the classical test theory. Finally, Cronbach’s alpha was used.Results: Measure of concordance showed scores considered adequate and excellent. The item discrimination index obtained a rating of “excellent” and suggested the preservation of all items. The discrimination coefficient scores are >0.74. The global internal consistency of the HBSCQ was 0.384. HBSCQ specification between groups of internal consistency for the

  8. The environmental monitoring of Cultural Heritage through Low Cost strategies: The frescoes of the crypt of St. Francesco d'Assisi's, Irsina (Basilicata, Southern Italy)

    Science.gov (United States)

    Sileo, Maria; Gizzi, Fabrizio; Masini, Nicola

    2015-04-01

    proved the capability and reliability of the designed low cost monitoring system for investigating the indoor microclimate in relation with decay pathologies. Acknowledgements The authors thank Basilicata Region for supporting this activity in the framework of the Project "PRO_CULT" (Advanced methodological approaches and technologies for Protection and Security of Cultural Heritage) financed by Regional Operational Programme ERDF 2007/2013 [1] M. Sileo, M. Biscione, F.T. Gizzi, N. Masini & M.I. Martinez-Garrido, 2014 - Low cost strategies for the environmental monitoring of Cultural Heritage: Preliminary data from the crypt of St. Francesco d'Assisi, Irsina (Basilicata, Southern Italy). Science, Technology and Cultural Heritage, Edited by Miguel Angel Rogerio-Candelera, 27-34. ISBN: 978-1-138-02744-2.

  9. Urban and Transport Planning Related Exposures and Mortality: A Health Impact Assessment for Cities.

    Science.gov (United States)

    Mueller, Natalie; Rojas-Rueda, David; Basagaña, Xavier; Cirach, Marta; Cole-Hunter, Tom; Dadvand, Payam; Donaire-Gonzalez, David; Foraster, Maria; Gascon, Mireia; Martinez, David; Tonne, Cathryn; Triguero-Mas, Margarita; Valentín, Antònia; Nieuwenhuijsen, Mark

    2017-01-01

    , Gascon M, Martinez D, Tonne C, Triguero-Mas M, Valentín A, Nieuwenhuijsen M. 2017. Urban and transport planning related exposures and mortality: a health impact assessment for cities. Environ Health Perspect 125:89-96; http://dx.doi.org/10.1289/EHP220.

  10. Development and clinical implementation of a new template for MRI-based intracavitary/interstitial gynecologic brachytherapy for locally advanced cervical cancer: from CT-based MUPIT to the MRI compatible Template Benidorm. Ten years of experience

    Directory of Open Access Journals (Sweden)

    Silvia Rodríguez Villalba

    2016-10-01

    Full Text Available Purpose : To study outcome and toxicity in 59 patients with locally advanced cervix carcinoma treated with computed tomography (CT-based Martinez universal perineal interstitial template (MUPIT and the new magnetic resonance imaging (MRI-compatible template Benidorm (TB. Material and methods: From December 2005 to October 2015, we retrospectively analyzed 34 patients treated with MUPIT and 25 treated with the TB. Six 4 Gy fractions were prescribed to the clinical target volume (CTV combined with external beam radiotherapy (EBRT. The organs at risk (OARs and the CTV were delineated by CT scan in the MUPIT implants and by MRI in the TB implants. Dosimetry was CT-based for MUPIT and exclusively MRI-based for TB. Dose values were biologically normalized to equivalent doses in 2 Gy fractions (EQD2. Results : Median CTV volumes were 163.5 cm3 for CT-based MUPIT (range 81.8-329.4 cm3 and 91.9 cm3 for MRI-based TB (range 26.2-161 cm3. Median D90 CTV (EBRT + BT was 75.8 Gy for CT-based MUPIT (range 69-82 Gy and 78.6 Gy for MRI-based TB (range 62.5-84.2. Median D2cm3 for the rectum was 75.3 Gy for CT-based MUPIT (range 69.8-132.1 Gy and 69.9 Gy for MRI-based TB (range 58.3-83.7 Gy. Median D2cm3 for the bladder was 79.8 Gy for CT-based MUPIT (range 71.2-121.1 Gy and 77.1 Gy for MRI-based TB (range 60.5-90.8 Gy. Local control (LC was 88%. Overall survival (OS, disease free survival (DFS, and LC were not statistically significant in either group. Patients treated with CT-based MUPIT had a significantly higher percentage of rectal bleeding G3 (p = 0.040 than those treated with MRI-based TB, 13% vs. 2%. Conclusions : Template Benidorm treatment using MRI-based dosimetry provides advantages of MRI volume definition, and allows definition of smaller volumes that result in statistically significant decreased rectal toxicity compared to that seen with CT-based MUPIT treatment.

  11. Fluorescence resonance energy transfer-based real-time polymerase chain reaction method without DNA extraction for the genotyping of F5, F2, F12, MTHFR, and HFE

    Directory of Open Access Journals (Sweden)

    Martinez-Serra J

    2014-06-01

    Full Text Available Jordi Martinez-Serra,1 Juan Robles,2 Antoni Nicolàs,3 Antonio Gutierrez,1 Teresa Ros,1 Juan Carlos Amat,1 Regina Alemany,4 Oliver Vögler,4 Aina Abelló,2 Aina Noguera,2 Joan Besalduch1 1Department of Hematology, 2Department of Clinical Analysis, Hospital Universitary Son Espases, Palma de Mallorca, Spain; 3ECOGEN, Barcelona, 4Department of Cell Biology, University of the Balearic Islands, Palma de Mallorca, Spain Abstract: Blood samples are extensively used for the molecular diagnosis of many hematological diseases. The daily practice in a clinical laboratory of molecular diagnosis in hematology involves using a variety of techniques, based on the amplification of nucleic acids. Current methods for polymerase chain reaction (PCR use purified genomic DNA, mostly isolated from total peripheral blood cells or white blood cells (WBC. In this paper we describe a real-time fluorescence resonance energy transfer-based method for genotyping directly from blood cells. Our strategy is based on an initial isolation of the WBCs, allowing the removal of PCR inhibitors, such as the heme group, present in the erythrocytes. Once the erythrocytes have been lysed, in the LightCycler® 2.0 Instrument, we perform a real-time PCR followed by a melting curve analysis for different genes (Factors 2, 5, 12, MTHFR, and HFE. After testing 34 samples comparing the real-time crossing point (CP values between WBC (5×106 WBC/mL and purified DNA (20 ng/µL, the results for F5 Leiden were as follows: CP mean value for WBC was 29.26±0.566 versus purified DNA 24.79±0.56. Thus, when PCR was performed from WBC (5×106 WBC/mL instead of DNA (20 ng/µL, we observed a delay of about 4 cycles. These small differences in CP values were similar for all genes tested and did not significantly affect the subsequent analysis by melting curves. In both cases the fluorescence values were high enough, allowing a robust genotyping of all these genes without a previous DNA purification

  12. xCELLigence system for real-time label-free monitoring of growth and viability of cell lines from hematological malignancies

    Directory of Open Access Journals (Sweden)

    Martinez-Serra J

    2014-06-01

    Full Text Available Jordi Martinez-Serra,1 Antonio Gutierrez,1 Saúl Muñoz-Capó,1 María Navarro-Palou,1 Teresa Ros,1 Juan Carlos Amat,1 Bernardo Lopez,1 Toni F Marcus,1 Laura Fueyo,2 Angela G Suquia,2 Jordi Gines,3 Francisco Rubio,1 Rafael Ramos,4 Joan Besalduch11Department of Hematology, 2Department of Clinical Analysis, 3Department of Pharmacy, 4Department of Pathology, University Hospital Son Espases, Palma de Mallorca, Balearic Islands, SpainAbstract: The xCELLigence system is a new technological approach that allows the real-time cell analysis of adherent tumor cells. To date, xCELLigence has not been able to monitor the growth or cytotoxicity of nonadherent cells derived from hematological malignancies. The basis of its technology relies on the use of culture plates with gold microelectrodes located in their base. We have adapted the methodology described by others to xCELLigence, based on the pre-coating of the cell culture surface with specific substrates, some of which are known to facilitate cell adhesion in the extracellular matrix. Pre-coating of the culture plates with fibronectin, compared to laminin, collagen, or gelatin, significantly induced the adhesion of most of the leukemia/lymphoma cells assayed (Jurkat, L1236, KMH2, and K562. With a fibronectin substrate, nonadherent cells deposited in a monolayer configuration, and consequently, the cell growth and viability were robustly monitored. We further demonstrate the feasibility of xCELLigence for the real-time monitoring of the cytotoxic properties of several antineoplastic agents. In order to validate this technology, the data obtained through real-time cell analysis was compared with that obtained from using the 3-(4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide method. This provides an excellent label-free tool for the screening of drug efficacy in nonadherent cells and discriminates optimal time points for further molecular analysis of cellular events associated with treatments

  13. Frequency and risk factors associated with dry eye in patients attending a tertiary care ophthalmology center in Mexico City

    Directory of Open Access Journals (Sweden)

    Martinez JD

    2016-07-01

    Full Text Available Jaime D Martinez,1 Anat Galor,2,3 Nallely Ramos-Betancourt,1 Andrés Lisker-Cervantes,1 Francisco Beltrán,1 Jorge Ozorno-Zárate,1 Valeria Sánchez-Huerta,1 Marco-Antonio Torres-Vera,1 Everardo Hernández-Quintela1 1Cornea and External Diseases Service, Asociación Para Evitar la Ceguera en Mexico (Association to prevent blindness in Mexico, Universidad Nacional Autónoma de México, Mexico City, Mexico; 2Department of Ophthalmology, Miami Veterans Affairs Medical Center, 3Cornea and External Diseases Division, Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA Purpose: The purpose of this study was to ascertain the frequency and risk factors of dry eye (DE among patients attending a tertiary care ophthalmology center in Mexico.Methods: Approximately 338 consecutive new patients attending a tertiary care ophthalmology center in Mexico City underwent an ocular surface examination, which included tear film break-up time, fluorescein corneal staining, Schirmer’s test, and evaluation of meibum quality. Symptoms of DE were evaluated by the Ocular Surface Disease Index and Dry Eye Questionnaire-5. Information on demographics, exposures, past medical and ocular history, and medications was also collected.Results: The frequency of severe DE symptoms was found to be 43% based on the Ocular Surface Disease Index and 30% based on Dry Eye Questionnaire-5. Risk factors significantly associated with increased DE symptoms included dry mouth and gastrointestinal ulcer medications. With regard to signs, aqueous tear deficiency was a less-frequent finding (22% in our population than evaporative deficiency (94%. Risk factors associated with aqueous tear deficiency were dry mouth and diuretic use. No risk factors were associated with evaporative deficiency. Risk factors associated with meibomian gland dysfunction included old age, male sex, arthritis, and use of an antihypertensive. The only risk factor associated with corneal staining was dry

  14. Effects of inhaled anesthetic isoflurane on long-term potentiation of CA3 pyramidal cell afferents in vivo

    Directory of Open Access Journals (Sweden)

    Ballesteros KA

    2012-11-01

    Full Text Available Kristen A Ballesteros,1 Angela Sikorski,2 James E Orfila,3 Joe L Martinez Jr41Department of Biology, The University of Texas at San Antonio, San Antonio, TX, USA; 2Texas A&M University Texarkana, Texarkana, TX, USA; 3University of Colorado in Denver, Denver, CO, USA; 4University of Illinois in Chicago, Chicago, IL, USAAbstract: Isoflurane is a preferred anesthetic, due to its properties that allow a precise concentration to be delivered continually during in vivo experimentation. The major mechanism of action of isoflurane is modulation of the γ-amino butyric acid (GABAA receptor-chloride channel, mediating inhibitory synaptic transmission. Animal studies have shown that isoflurane does not cause cell death, but it does inhibit cell growth and causes long-term hippocampal learning deficits. As there are no studies characterizing the effects of isoflurane on electrophysiological aspects of long-term potentiation (LTP in the hippocampus, it is important to determine whether isoflurane alters the characteristic responses of hippocampal afferents to cornu ammonis region 3 (CA3. We investigated the effects of isoflurane on adult male rats during in vivo induction of LTP, using the mossy fiber pathway, the lateral perforant pathway, the medial perforant pathway, and the commissural CA3 (cCA3 to CA3, with intracranial administration of Ringer’s solution, naloxone, RS-aminoindan-1, 5-dicarboxylic acid (AIDA, or 3-[(R-2-carboxypiperazin-4-yl]-propo-2-enyl-1-phosphonic acid (CPP. Then, we compared these responses to published electrophysiological data, using sodium pentobarbital as an anesthetic, under similar experimental conditions. Our results showed that LTP was exhibited in animals anesthetized with isoflurane under vehicle conditions. With the exception of AIDA in the lateral perforant pathway, the defining characteristics of the four pathways appeared to remain intact, except for the observation that LTP was markedly reduced in animals

  15. Mannose-binding lectin deficiency and acute exacerbations of chronic obstructive pulmonary disease

    Directory of Open Access Journals (Sweden)

    Woodruff PG

    2012-11-01

    Full Text Available Richard K Albert,1 John Connett,2 Jeffrey L Curtis,3,4 Fernando J Martinez,3 MeiLan K Han,3 Stephen C Lazarus,5 Prescott G Woodruff51Medicine Service, Denver Health and Department of Medicine, University of Colorado Denver, Denver, CO, 2Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN, 3Pulmonary and Critical Care Medicine, Department of Medicine, University of Michigan, Ann Arbor, MI, 4Pulmonary and Critical Care Medicine, VA Medical Center, Ann Arbor, MI, 5Pulmonary and Critical Care Medicine, Department of Medicine, and Cardiovascular Research Institute, University of California, San Francisco, CA, USABackground: Mannose-binding lectin is a collectin involved in host defense against infection. Whether mannose-binding lectin deficiency is associated with acute exacerbations of chronic obstructive pulmonary disease is debated.Methods: Participants in a study designed to determine if azithromycin taken daily for one year decreased acute exacerbations had serum mannose-binding lectin concentrations measured at the time of enrollment.Results: Samples were obtained from 1037 subjects (91% in the trial. The prevalence of mannose-binding lectin deficiency ranged from 0.5% to 52.2%, depending on how deficiency was defined. No differences in the prevalence of deficiency were observed with respect to any demographic variable assessed, and no differences were observed in time to first exacerbation, rate of exacerbations, or percentage of subjects requiring hospitalization for exacerbations in those with deficiency versus those without, regardless of how deficiency was defined.Conclusion: In a large sample of subjects with chronic obstructive pulmonary disease selected for having an increased risk of experiencing an acute exacerbation of chronic obstructive pulmonary disease, only 1.9% had mannose-binding lectin concentrations below the normal range and we found no association between mannose-binding lectin

  16. Stent tunnel technique to save thrombosed native hemodialysis fistula with extensive venous aneurysm

    Directory of Open Access Journals (Sweden)

    Rabellino M

    2017-07-01

    Full Text Available Martin Rabellino,1 Guillermo J Rosa-Diez,2 Sergio A Shinzato,1 Pablo Rodriguez,1 Oscar A Peralta,1 Maria S Crucelegui,2 Rosario Luxardo,2 Agustina Heredia-Martinez,2 Mariela I Bedini-Rocca,2 Ricardo D García-Mónaco1 1Department of Angiography and Endovascular Therapy, 2Department of Nephrology, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina Introduction and purpose: The increasing number of patients undergoing hemodialysis and the limited number of access sites have resulted in an increasing number of techniques to maintain vascular access for hemodialysis. Thrombosed arteriovenous (AV fistulas with large venous aneurysms have poor treatment results, with both endovascular and surgical techniques, leading to a high rate of definitive AV access loss. The purpose of this study was to review the feasibility and initial results of this novel endovascular treatment of thrombosed AV fistulas with large venous aneurysms.Materials and methods: A novel endovascular treatment technique of inserting nitinol auto-expandable uncovered stents stretching through the whole puncture site area, thus creating a tunnel inside the thrombus, was retrospectively analyzed and described.Results: A total of 17 stents were placed in 10 hemodialysis fistulas, with a mean venous coverage length of 17.8 cm. In all the cases, 100% technical success was achieved, with complete restoration of blood flow in all patients. There were no procedure-related complications. The mean follow-up was 167 days (range 60–420 days, with a primary and assisted patency of 80% and 100%, respectively. No multiple trans-stent struts-related complications were observed. Three stent fractures were diagnosed with plain films at the site of puncture without consequence in the venous access permeability.Conclusion: The “stent tunnel technique” is a feasible, safe and effective alternative to salvage native hemodialysis access, thus extending the function of the venous access with

  17. Understanding Extension in the Southern Marianas and the Challenger Deep: a 21ST Century Geoscientific Challenge

    Science.gov (United States)

    Stern, R. J.; Ribeiro, J. M.; Martinez, F.; Ohara, Y.

    2017-12-01

    The Challenger Deep (CD) is the deepest spot on Earth's solid surface and the reasons for its great depth are controversial. In general, trench depths (without sediments) are thought to reflect slab age; old oceanic lithosphere arrives at the trench deeper so similar downbending makes deeper trenches than young oceanic lithosphere. Slab tears and edges and short slabs also may help trenches deepen by making it easier to roll back. In the case of the CD, we are unsure of subducted oceanic lithosphere age because this lies near the juncture of Jurassic and Oligocene crusts. A slab edge to the west and a slab tear to the east may also help the Pacific plate roll back and contribute to its depth. A possible unexamined reason for CD's great depth may be strong extension of the overlying plate associated with opening of the Mariana Trough backarc basin (MT-BAB). GPS on islands indicate southward-increasing extension rates of at least 45mm/yr at the latitude of Guam (Kato et al. 2003 GRL; see Martinez et al. T037 for more info); extension rates are likely to be greater in the MT-BAB north of CD. There are few convergent margins where strong extension affects the overriding plate. Overriding plate extension may help deepen trenches by narrowing the plate coupling zone (Gvirtzman and Stern 2003 Tectonics). Asthenosphere outflow from the shrinking Philippine Sea plate could also push against the slab to depress it. The region around the CD is very deep water, presenting major challenges for future study. The combined deepwater assets and brainpower of the US, Japan, and China are needed to do this work. Both subducting and overriding plates need study. For the downgoing plate, we need IODP drilling and refraction studies to determine its age and crustal and lithospheric structure; electromagnetic sounding would also help reveal upper plate structure. We need passive OBS studies to map slab tears and edges. We need to better understand the tectonic evolution of the MT

  18. Ceftriaxone and clavulanic acid induce antiallodynia and anti-inflammatory effects in rats using the carrageenan model

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    Ochoa-Aguilar A

    2018-05-01

    Full Text Available Abraham Ochoa-Aguilar,1,2 Rosa Ventura-Martinez,1 Marco Antonio Sotomayor-Sobrino,1 Ruth Jaimez,1 Ulises Coffeen,3 Ariadna Jiménez-González,2 Luis Gerardo Balcázar-Ochoa,1 Rafael Pérez-Medina-Carballo,2 Rodolfo Rodriguez,1 Ricardo Plancarte-Sánchez4 1Pharmacology Department, Faculty of Medicine, National Autonomous University of Mexico, Mexico City, México; 2Research Department, Mexican Faculty of Medicine, La Salle University, Mexico City, México; 3Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Mexico City, México; 4Pain Clinic, National Cancer Institute of Mexico, Mexico City, México Introduction: Ceftriaxone (CFX and clavulanic acid (CA are 2 β-lactam molecules widely used as antibiotics. However, several reports of their antiallodynic properties have been published in recent years. Although this effect has been considered mostly due to a GLT1 overexpression, these molecules have also been proven to induce direct immunomodulation. In this work, we determine the acute analgesic effect of CFX and CA in an inflammatory pain model and assess if their administration may induce anti-inflammatory effects. Methods: The carrageenan (Carr test was used as an inflammatory pain model. Both mechanical and thermal responses were analyzed after CFX and CA administration at different times. A plethysmometer was used to determine inflammation. Also, TNF-α and IL-10 serum concentrations were determined by enzyme-linked immunosorbent assay. Results: Both CFX and CA induced a significant thermal antiallodynic effect 3 and 24 h after administration. Furthermore, CA induced a mechanical antiallodynic effect 30, 60, and 90 min after administration. Moreover, a significant anti-inflammatory effect was found for both molecules 24 h after Carr injection. Also, both CA and CFX modulated TNF-α and IL-10 serum concentrations at different times. Conclusion: Our results provide evidence that both CFX and CA cause an analgesic effect on a Carr

  19. Effect of nerve injury on the number of dorsal root ganglion neurons and autotomy behavior in adult Bax-deficient mice

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    Lyu C

    2017-08-01

    Full Text Available Chuang Lyu,1,2 Gong-Wei Lyu,3 Aurora Martinez,4 Tie-Jun Sten Shi4 1State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Harbin, People’s Republic of China; 2Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden; 3Department of Neurology, 1st Hospital of Harbin Medical University, Harbin, People’s Republic of China; 4Department of Biomedicine, University of Bergen, Bergen, Norway Background: The proapoptotic molecule BAX, plays an important role in mitochondrial apoptotic pathway. Dorsal root ganglion (DRG neurons depend on neurotrophic factors for survival at early developmental stages. Withdrawal of neurotrophic factors will induce apoptosis in DRG neurons, but this type of cell death can be delayed or prevented in neonatal Bax knockout (KO mice. In adult animals, evidence also shows that DRG neurons are less dependent upon neurotrophic factors for survival. However, little is known about the effect of Bax deletion on the survival of normal and denervated DRG neurons in adult mice. Methods: A unilateral sciatic nerve transection was performed in adult Bax KO mice and wild-type (WT littermates. Stereological method was employed to quantify the number of lumbar-5 DRG neurons 1 month post-surgery. Nerve injury-induced autotomy behavior was also examined on days 1, 3, and 7 post-surgery. Results: There were significantly more neurons in contralateral DRGs of KO mice as compared with WT mice. The number of neurons was reduced in ipsilateral DRGs in both KO and WT mice. No changes in size distributions of DRG neuron profiles were detected before or after nerve injury. Injury-induced autotomy behavior developed much earlier and was more serious in KO mice. Conclusion: Although postnatal death or loss of DRG neurons is partially prevented by Bax deletion, this effect cannot interfere with long-term nerve injury-induced neuronal loss. The exaggerated self

  20. The influence of sex and gonadal hormones on sleep disorders

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    Orff HJ

    2014-06-01

    Full Text Available Henry J Orff, Charles J Meliska, L Fernando Martinez, Barbara L Parry Department of Psychiatry, University of California, San Diego, CA, USA Abstract: Sleep disorders such as insomnia, sleep-related breathing disorders, circadian rhythm disorders, and sleep-related movement disorders are a significant public health issue, affecting approximately 40 million people in the US each year. Sleep disturbances are observed in both men and women, though prevalence rates often differ between the sexes. In general, research suggests that women more frequently report subjective complaints of insomnia, yet show better sleep than men when evaluated on objective measures of sleep. Men are more likely to be diagnosed with obstructive sleep apnea than women, though rates of obstructive sleep apnea increase after menopause and may be generally underdiagnosed in women. Although circadian rhythm disorders are equally prevalent in men and women, studies find that women typically have earlier bedtimes and exhibit altered temperature and melatonin rhythms relative to men. Lastly, movement disorders appear to be more prevalent in women than men, presumably due to higher rates of anemia and increased risks associated with pregnancy in women. Although gonadal hormones would be expected to play a significant role in the development and/or exacerbation of sleep disturbances, no causal link between these factors has been clearly established. In large part, the impact of hormones on sleep disturbances is significantly confounded by factors such as psychiatric, physical, and lifestyle concerns, which may play an equal or greater role in the development and/or exacerbation of sleep disturbances than do hormonal factors. Current standard of care for persons with sleep disorders includes use of psychological, pharmacologic, and/or medical device supported interventions. Hormonal-based treatments are not typically recommended given the potential for long-term adverse health

  1. Retrospective analysis of role of interstitial brachytherapy using template (MUPIT in locally advanced gynecological malignancies

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    Nandwani Pooja

    2007-01-01

    Full Text Available Aim : The aim of this retrospective study was to assess treatment outcomes for patients with locally advanced gynecological malignancies being treated with interstitial brachytherapy using Martinez universal perineal interstitial template (MUPIT and to study the acute and late sequelae and survival after treatment by this technique. Materials and Methods : Ninety seven patients untreated with histopathological confirmation of carcinoma of cervix (37 vault (40 and vagina (20 were treated by combination of external beam RT (EBRT using megavoltage irradiation to pelvis to dose of 4000-5000 cGy followed by interstitial brachytherapy using MUPIT between September 2001 to March 2005. Median age was 46 years. Only those patients who were found unsuitable for conventional brachytherapy or in whom intracavitatory radiotherapy was found to be unlikely to encompass a proper dose distribution were treated by interstitial template brachytherapy using MUPIT application and were enrolled in this study. The dose of MUPIT was 1600-2400 cGy in 4-6# with 400 cGy /# and two fractions a day with minimum gap of six hours in between two fractions on micro-HDR. Criteria for inclusion of patients were as follows: Hb minimum 10 gm/dl, performance status - 70% or more (Karnofsy scale, histopathological confirmation FIGO stage IIB-IIIB (excluding frozen pelvis. Results : Among the 97 patients studied, 12 patients lost to follow-up and hence they were excluded from the study. Follow-up of rest of the patients was then done up to September 2006. The duration of follow-up was in the range of 20-60 months. Parameters studied were local control rate, complication rate, mortality rate and number of patients developing systemic metastasis. Local control was achieved in 56/85 (64.7% and complication rate was 15/85 (17.6%. Local control was better for nonbulky tumors compared bulky tumors irrespective of stage of disease. Local control was better in patients with good regression of

  2. Chromium Stable Isotope Fractionation - An Indicator of Hexavalent Chromium Reduction.

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    Ellis, A.; Johnson, T. M.; Bullen, T. D.

    2001-12-01

    Chromium is a common anthropogenic contaminant in surface water and ground water, and is also of interest in oceanography. It is redox-active; the two common valences in natural waters are Cr(VI), which is highly soluble and toxic, and Cr(III), which is relatively insoluble. Redox reactions thus control Cr mobility in aqueous solutions, and reduction of Cr(VI) to Cr(III) is the most important reaction controlling attenuation of Cr in groundwater. Our results show that Cr(VI) reduction favors the lighter isotopes and leads to enrichment of heavier isotopes in the remaining Cr(VI). Cr isotope measurements thus show great promise as indicators of Cr(VI) reduction. We report here the first measurements of the magnitude of Cr isotope fractionation during Cr(VI) reduction and variations in δ 53Cr values obtained from three contaminated sites. Experiments were conducted to measure Cr isotope fractionation during Cr(VI) reduction by suspensions of magnetite and unamended sediments from a local pond, Urbana, IL and San Francisco Estuary near Martinez, CA. Suspensions were incubated anaerobically with constant shaking, and complete Cr(VI) reduction occurred within a few days. Cr(VI) from intermediate time points in the experiments was purified via ion exchange and 53Cr/52Cr ratios were measured via TIMS with a double isotope spike. The instantaneous per mil fractionation, ɛ , was calculated assuming a Rayleigh fractionation model. The ɛ for Cr(VI) reduction on magnetite surfaces yielded a fractionation of -3.5 ‰ . The ɛ values for the pond and estuary sediments were -3.5 ‰ and -3.3 ‰ respectively. The size of this Cr isotope fractionation is encouraging, as current precision is 0.2 \\permil. δ 53Cr values in dissolved Cr(VI) from three contaminated sites range from 1.1 ‰ to 5.8 ‰ , suggesting that Cr(VI) reduction has occurred and has induced isotopic fractionation in these settings. δ 53Cr values measured from Cr(VI) in plating baths show little or no

  3. Towards Greenland Glaciation: cumulative or abrupt transition?

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    Ramstein, Gilles; Tan, Ning; Ladant, Jean-baptiste; Dumas, Christophe; Contoux, Camille

    2017-04-01

    During the mid-Pliocene warming period (3-3.3 Ma BP), the global annual mean temperatures inferred by data and model studies were 2-3° warmer than pre-industrial values. Accordingly, Greenland ice sheet volume is supposed to reach at the most, only half of that of present-day [Haywood et al. 2010]. Around 2.7-2.6 Ma BP, just ˜ 500 kyr after the warming peak of mid-Pliocene, the Greenland ice sheet has reached its full size [Lunt et al. 2008]. A crucial question concerns the evolution of the Greenland ice sheet from half to full size during the 3 - 2.5 Ma period. Data show a decreasing trend of atmospheric CO2 concentration from 3 Ma to 2.5 Ma [Seki et al.2010; Bartoli et al. 2011; Martinez et al. 2015]. However, a recent study [Contoux et al. 2015] suggests that a lowering of CO2 is not sufficient to initiate a perennial glaciation on Greenland and must be combined with low summer insolation to preserve the ice sheet during insolation maxima. This suggests rather a cumulative process than an abrupt event. In order to diagnose the evolution of the ice sheet build-up, we carry on, for the first time, a transient simulation of climate and ice sheet evolutions from 3 Ma to 2.5 Ma. This strategy enables us to investigate the waxing and waning of the ice sheet during several orbital cycles. We use a tri-dimensional interpolation method designed by Ladant et al. (2014), which allows the evolution of CO2 concentration and of orbital parameters, and the evolution of the Greenland ice sheet size to be taken into account. By interpolating climatic snapshot simulations ran with various possible combinations of CO2, orbits and ice sheet sizes, we can build a continuous climatic forcing that is then used to provide 500 kyrs-long ice sheet simulations. With such a tool, we may offer a physically based answer to different CO2 reconstructions scenarios and analyse which one is the most consistent with Greenland ice sheet buildup.

  4. Iron fertilization of the Subantarctic Ocean during the last ice age

    Science.gov (United States)

    Martinez-Garcia, A.

    2015-12-01

    Dust has the potential to modify global climate by influencing the radiative balance of the atmosphere and by supplying iron and other essential limiting micronutrients to the ocean. The scarcity of iron limits marine productivity and carbon uptake in one-quarter of the world ocean where the concentration of major nutrients (phosphorus and nitrogen) is perennially high. The Southern Ocean is the region where variations in iron availability can have the largest effect on Earth's carbon cycle through its fertilizing effect on marine ecosystems. Paleoceanographic records from the Subantarctic Atlantic have revealed a remarkable correlation between phytoplankton productivity and aeolian iron flux during glacial periods supporting the iron fertilization hypothesis. In addition, a recent study has shown that peak glacial times and millennial cold events were nearly universally associated not only with increases in dust flux and export production, but also with an increase in nutrient consumption (the last indicated by higher foraminifera-bound δ15N) (Martinez-Garcia et al. 2014). This combination of changes is uniquely consistent with ice age iron fertilization of the Subantarctic Atlantic. The strengthening of the biological pump associated with the observed increase in Subantarctic nutrient consumption during the high-dust intervals of the last two ice ages can explain up to ~40 ppm of the CO2 decrease that characterizes the transitions from mid-climate states to full ice age conditions. However, the impact of iron fertilization in other sectors of the Southern Ocean characterized by lower ice age dust fluxes than the Atlantic remains unclear. A series of recently published records from the Subantarctic Pacific indicate that dust deposition and marine export production were three times higher during glacial periods than during interglacials (Lamy et al. 2014). Here we present new measurements of foraminifera-bound nitrogen isotopes in a sediment core located in the

  5. The Morelia-Acambay Fault System

    Science.gov (United States)

    Velázquez Bucio, M.; Soria-Caballero, D.; Garduño-Monroy, V.; Mennella, L.

    2013-05-01

    The Trans-Mexican Volcanic Belt (TMVB) is one of the most actives and representative zones of Mexico geologically speaking. Research carried out in this area gives stratigraphic, seismologic and historical evidence of its recent activity during the quaternary (Martinez and Nieto, 1990). Specifically the Morelia-Acambay faults system (MAFS) consist in a series of normal faults of dominant direction E - W, ENE - WSW y NE - SW which is cut in center west of the Trans-Mexican Volcanic Belt. This fault system appeared during the early Miocene although the north-south oriented structures are older and have been related to the activity of the tectonism inherited from the "Basin and Range" system, but that were reactivated by the east- west faults. It is believed that the activity of these faults has contributed to the creation and evolution of the longed lacustrine depressions such as: Chapala, Zacapu, Cuitzeo, Maravatio y Acambay also the location of monogenetic volcanoes that conformed the Michoacan-Guanajuato volcanic field (MGVF) and tend to align in the direction of the SFMA dominant effort. In a historical time different segments of the MAFS have been the epicenter of earthquakes from moderated to strong magnitude like the events of 1858 in Patzcuaro, Acambay in 1912, 1979 in Maravatio and 2007 in Morelia, among others. Several detailed analysis and semi-detailed analysis through a GIS platform based in the vectorial archives and thematic charts 1:50 000 scaled from the data base of the INEGI which has allowed to remark the influence of the MAFS segments about the morphology of the landscape and the identification of other structures related to the movement of the existent faults like fractures, alignments, collapses and others from the zone comprehended by the northwest of Morelia in Michoacán to the East of Acambay, Estado de México. Such analysis suggests that the fault segments possess a normal displacement plus a left component. In addition it can be

  6. Wetland Responses to Sea Level Rise in the Northern Gulf of Mexico

    Science.gov (United States)

    Alizad, K.; Bilskie, M. V.; Hagen, S. C.; Medeiros, S. C.; Morris, J. T.

    2016-12-01

    Coastal regions are vulnerable to flood risk due to climate change, sea level rise, and wetland losses. The Northern Gulf of Mexico (NGOM) is a region in which extreme events are projected to be more intense under climate change and sea level rise scenarios [Wang et al., 2013; Bilskie et al., 2014]. Considering increased frequency and intensity of coastal flooding, wetlands are valuable natural resources that protect shorelines by dissipating waves and storm surges [Costanza et al., 2008]. Therefore, it is critical to investigate the response of salt marsh systems in different estuaries to sea level rise in the NGOM and their effects on storm surges to inform coastal managers to choose effective restoration plans. This research applies the coupled Hydro-MEM model [Alizad et al., 2016] to study three different estuarine systems in the NGOM. The model incorporates both sea level rise rate and feedbacks between physics and biology by coupling a hydrodynamic (ADCIRC) and salt marsh (MEM) model. The results of the model provide tidal hydrodynamics and biomass density change under four sea level rise projections during a 100-year period. The results are used to investigate marsh migration path in the estuarine systems. In addition, this study shows how marsh migration and biomass density change can impact storm surge modeling. The results imply the broader impacts of sea level rise on the estuarine systems in the NGOM. ReferencesAlizad, K., S. C. Hagen, J. T. Morris, P. Bacopoulos, M. V. Bilskie, J. Weishampel, and S. C. Medeiros (2016), A coupled, two-dimensional hydrodynamic-marsh model with biological feedback, Ecological Modeling, 327, 29-43. Bilskie, M. V., S. C. Hagen, S. C. Medeiros, and D. L. Passeri (2014), Dynamics of sea level rise and coastal flooding on a changing landscape, Geophysical Research Letters, 41(3), 927-934. Costanza, R., O. Pérez-Maqueo, M. L. Martinez, P. Sutton, S. J. Anderson, and K. Mulder (2008), The Value of Coastal Wetlands for Hurricane

  7. Image and laparoscopic guided interstitial brachytherapy for locally advanced primary or recurrent gynaecological cancer using the adaptive GEC ESTRO target concept

    International Nuclear Information System (INIS)

    Fokdal, Lars; Tanderup, Kari; Nielsen, Soren Kynde; Christensen, Henrik Kidmose; Rohl, Lisbeth; Pedersen, Erik Morre; Schonemann, Niels Kim; Lindegaard, Jacob Christian

    2011-01-01

    Purpose: To retrospectively assess treatment outcome of image and laparoscopic guided interstitial pulsed dose rate brachytherapy (PDR-BT) for locally advanced gynaecological cancer using the adaptive GEC ESTRO target concept. Materials and methods: Between June 2005 and December 2010, 28 consecutive patients were treated for locally advanced primary vaginal (nine), recurrent endometrial (12) or recurrent cervical cancer (seven) with combined external beam radiotherapy (EBRT) and interstitial PDR-BT. Treatment was initiated with whole pelvic EBRT to a median dose of 45 Gy followed by PDR-BT using the Martinez Universal Perineal Interstitial Template (MUPIT). All implants were virtually preplanned using MRI of the pelvis with a dummy MUPIT in situ. The GEC ESTRO high risk clinical target volume (HR CTV), intermediate risk clinical target volume (IR CTV) and the organs at risk (OAR) were contoured and a preplan for implantation was generated (BrachyVision, Varian). The subsequent implantation was performed under laparoscopic visualisation. Final contouring and treatment planning were done using a post-implant CT. Planning aim of PDR-BT was to deliver 30 Gy in 50 hourly pulses to HR CTV. Manual dose optimisation was performed with the aim of reaching a D90 > 80 Gy in the HR CTV calculated as the total biologically equivalent to 2 Gy fractions of EBRT and BT (EQD2). Dose to the OAR were evaluated using dose volume constraints for D 2cc of 90 Gy for bladder and 70 Gy for rectum and sigmoid. Results: For HR CTV the median volume was 26 cm 3 (7-91 cm 3 ). Coverage of the HR CTV was 97% (90-100%) and D90 was 82 Gy (77-88 Gy). The D 2cc for bladder, rectum, and sigmoid were 65 Gy (47-81 Gy), 61 Gy (50-77 Gy), and 52 Gy (44-68 Gy), respectively. Median follow up was 18 months (6-61 months). The actuarial 2 years local control rate was 92% (SE 5), while disease-free survival and overall survival were 59% (SE 11) and 74%, respectively (SE 10). No complications to the

  8. Professional Development for Graduate Students through Internships at Federal Labs: an NSF/USGS Collaboration

    Science.gov (United States)

    Snow, E.; Jones, E.; Patino, L. C.; Wasserman, E.; Isern, A. R.; Davies, T.

    2016-12-01

    In 2013 the White House initiated an effort to coordinate STEM education initiatives across federal agencies. This idea spawned several important collaborations, one of which is a set of National Science Foundation programs designed to place graduate students in federal labs for 2-12 months of their Ph.D. training. The Graduate Research Internship Program (GRIP) and the Graduate Student Preparedness program (GSP) each have the goal of exposing PhD students to the federal work environment while expanding their research tools and mentoring networks. Students apply for supplementary support to their Graduate Research Fellowship (GRIP) or their advisor's NSF award (GSP). These programs are available at several federal agencies; the USGS is one partner. At the U.S. Geological Survey, scientists propose projects, which students can find online by searching USGS GRIP, or students and USGS scientists can work together to develop a research project. At NSF, projects are evaluated on both the scientific merit and the professional development opportunities they afford the student. The career development extends beyond the science (new techniques, data, mentors) into the professional activity of writing the proposal, managing the budget, and working in a new and different environment. The USGS currently has 18 GRIP scholars, including Madeline Foster-Martinez, a UC Berkeley student who spent her summer as a GRIP fellow at the USGS Pacific Coastal and Marine Science Center working with USGS scientist Jessica Lacy. Madeline's Ph.D. work is on salt marshes and she has studied geomorphology, accretion, and gas transport using a variety of research methods. Her GRIP fellowship allowed her to apply new data-gathering tools to the question of sediment delivery to the marsh, and build and test a model for sediment delivery along marsh edges. In addition, she gained professional skills by collaborating with a new team of scientists, running a large-scale field deployment, and

  9. SIMPOSIO "ASPECTOS MÉDICOS DE LA ERUPCIÓN DEL NEVADO DEL RUIZ". CONCLUSIONES PRELIMINARES

    Directory of Open Access Journals (Sweden)

    Academia Nacional de Medicina

    1986-12-01

    Full Text Available

    El Comité Organizador del Simposio "' Aspéctos Medicos de la Erupción Volcanica del Nevado del Ruiz". confor­mado por los doctores Pablo Gomez Martinez, Jose Felix Patino, Valentin Malagón, German Fernandez. Ivan Munera y Luis Jorge Perez, se permite informar a la opinion publica, las conclusiones preliminares a las que ha llegado despues de haber analizado todas las ponencias presentadas por las personas y entidades que atendieron sobrevivientes de la catastrofe de noviembre de 1985.

    1. Aspectos geológicos

    Colombia está situada en el area denominada Cinturón de Fuego, que envuelve el Oceano Pacifico y en su conformación geográfica se encuentran 30 volcanes, situados en su mayorla en la Cordillera Central. De estos, 11 están en mayor o menor actividad y 7 tienen historia de erupciones. Las capas geol6ógicas sobre las cuales se extiende el pals presentan zonas de elevada sismicidad

    Las caracterlsticas de la erupción del Nevado del Ruiz permiten clasificarlo como un volcan de tipo "'Pliniano- explosivo". que puede emitir enorme cantidad de gases y fragmentos sólidos a grandes velocidades y altas tempe­raturas, como tambien lodo caliente, con deshielo de las nieves perpetuas cuyo resultado es Ia formación del "lahar" que sepultó las poblaciones y cubrió extensas zonas de terreno. Estas erupciones se presentan de manera intermitente y su comportamiento es impredecible. Existe siempre la posibilidad de erupciones late­rales que aumentan su peligro y radio de acción.

    El "lahar" fue una avalancha de lodo que cubrió a la poblacion de Armero; lo componían materiales inorgánicos provenientes del volcan, mezclados con los materiales orgánicos presentes en las tierras fertiles dedicadas a la agricultura y la ganadería. Estudios microbiológicos demostraron la presencia de una rica flora bacteriana y de hongos...

  10. Del Malleus Maleficarum a los Feminicidios Actuales (From the Malleus Maleficarum to Current Femicides

    Directory of Open Access Journals (Sweden)

    Luis Alfonso Fajardo Sanchez

    2015-06-01

    Full Text Available The Malleus Maleficarum or Hammer of Witches (Krämer y Sprenger 1487 is a text that influenced the violation of human rights of women in the past, written with the aim of subjugating those who did not fit in religious or moral of the prevailing patriarchal stereotypes through torture, rape and burning of the genre, which undoubtedly is one of the first documented femicide. An analysis of that manual, in his philosophical and theological foundations, the crimes, the study of procedures and sanctions, and then we describe some elements of the concept femicide effectively calling as a form of genocide. Later on we will make some considerations to the tragic events in Colombia when María Berenice Hernandez Martinez was killed, allegedly by a group of people in the community that blamed her of being a witch. Finally, this will help us understand the historical foundations of patriarchy, such as the legal system. El Malleus Maleficarum o Martillo de las Brujas (Krämer y Sprenger 1487 es un texto que influenció la vulneración de los derechos humanos de las mujeres en épocas pasada, escrito con el objetivo de subyugar a aquellas que no encajaban en los estereotipos religiosos o morales del patriarcado imperante, a través de la tortura, violación y quema de este género, lo que sin duda, es uno de los primeros feminicidios documentados. Un análisis de dicho manual, en sus fundamentos filosóficos y teológicos, la tipificación de los delitos, el estudio de los procedimientos y sanciones, y después, vamos a describir algunos elementos del concepto femicidio calificándolo efectivamente, como una modalidad de genocidio. Luego realizaremos algunas consideraciones a los trágicos hechos sucedidos en Colombia cuando la señora Maria Berenice Hernández Martínez fue asesinada, presuntamente, por un grupo de personas de la comunidad que la culparon de ser una bruja. Finalmente, esto nos ayudará a entender los fundamentos históricos del patriarcado

  11. Virtual Reality for Management of Pain in Hospitalized Patients: Results of a Controlled Trial.

    Science.gov (United States)

    Tashjian, Vartan C; Mosadeghi, Sasan; Howard, Amber R; Lopez, Mayra; Dupuy, Taylor; Reid, Mark; Martinez, Bibiana; Ahmed, Shahzad; Dailey, Francis; Robbins, Karen; Rosen, Bradley; Fuller, Garth; Danovitch, Itai; IsHak, Waguih; Spiegel, Brennan

    2017-03-29

    Improvements in software and design and reduction in cost have made virtual reality (VR) a practical tool for immersive, three-dimensional (3D), multisensory experiences that distract patients from painful stimuli. The objective of the study was to measure the impact of a onetime 3D VR intervention versus a two-dimensional (2D) distraction video for pain in hospitalized patients. We conducted a comparative cohort study in a large, urban teaching hospital in medical inpatients with an average pain score of ≥3/10 from any cause. Patients with nausea, vomiting, dementia, motion sickness, stroke, seizure, and epilepsy and those placed in isolation were excluded. Patients in the intervention cohort viewed a 3D VR experience designed to reduce pain using the Samsung Gear Oculus VR headset; control patients viewed a high-definition, 2D nature video on a 14-inch bedside screen. Pre- and postintervention pain scores were recorded. Difference-in-difference scores and the proportion achieving a half standard deviation pain response were compared between groups. There were 50 subjects per cohort (N=100). The mean pain reduction in the VR cohort was greater than in controls (-1.3 vs -0.6 points, respectively; P=.008). A total of 35 (65%) patients in the VR cohort achieved a pain response versus 40% of controls (P=.01; number needed to treat=4). No adverse events were reported from VR. Use of VR in hospitalized patients significantly reduces pain versus a control distraction condition. These results indicate that VR is an effective and safe adjunctive therapy for pain management in the acute inpatient setting; future randomized trials should confirm benefit with different visualizations and exposure periods. Clinicaltrials.gov NCT02456987; https://clinicaltrials.gov/ct2/show/NCT02456987 (Archived by WebCite at http://www.webcitation.org/6pJ1P644S). ©Vartan C Tashjian, Sasan Mosadeghi, Amber R Howard, Mayra Lopez, Taylor Dupuy, Mark Reid, Bibiana Martinez, Shahzad Ahmed

  12. A Mental Health Storytelling Intervention Using Transmedia to Engage Latinas: Grounded Theory Analysis of Participants' Perceptions of the Story's Main Character.

    Science.gov (United States)

    Heilemann, MarySue V; Martinez, Adrienne; Soderlund, Patricia D

    2018-05-02

    development of the main character is valuable. Theoretical guidance, previous deidentified data from the target group, critique from key stakeholders and members of the target group, and preliminary testing are likely to enhance the main character's relatability and appropriateness, which can increase sustained engagement. ©MarySue V Heilemann, Adrienne Martinez, Patricia D Soderlund. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 02.05.2018.

  13. PREFACE: International Symposium on Ultrasound in the Control of Industrial Processes (UCIP 2012)

    Science.gov (United States)

    Segura, Luis Elvira; Resa López, Pablo; Salazar, Jordi; Benedito Fort, José Javier; Martínez Graullera, Óscar

    2012-12-01

    Multiple Scattering of Generic Waves in Particulate Composites' by Félix Alba Consulting. A total of 93 delegates from 21 countries participated actively in this event, and more than ten companies were involved through oral communications, tutorials, exhibition or sponsorship. Conference photograph Conference photograph Organizers Organizers SCIENTIFIC COMMITTEE Dr Luis Elvira, Centro de Acústica Aplicada y Evaluación No Destructiva (CAEND), UPM-CSIC, Spain Dr Pablo Resa, Centro de Acústica Aplicada y Evaluación No Destructiva (CAEND), UPM-CSIC, Spain Dr Oscar F Martinez-Graullera Centro de Acústica Aplicada y Evaluación No Destructiva (CAEND), UPM-CSIC, Spain Dr Jordi Salazar Department of Electronic Engineering Universitat Politècnica de Catalunya, Spain Dr Jose Benedito Universitat Politècnica de València, Spain ORGANIZING COMMITTEE Dr Luis Elvira, Centro de Acústica Aplicada y Evaluación No Destructiva (CAEND), UPM-CSIC, Spain Prof Malcolm J W Povey, Procter Department of Food Science University of Leeds, United Kingdom Dr Jordi Salazar, Department of Electronic Engineering Universitat Politècnica de Catalunya, Spain Dr Jose Benedito, Universitat Politècnica de València, Spain Dr Oscar F Martinez-Graullera, Centro de Acústica Aplicada y Evaluación No Destructiva (CAEND), UPM-CSIC, Spain Carmen Duran, Centro de Acústica Aplicada y Evaluación No Destructiva (CAEND), UPM-CSIC, Spain Dr Pablo Resa, Centro de Acústica Aplicada y Evaluación No Destructiva (CAEND), UPM-CSIC, Spain Dra Cristina Aparicio, Centro de Acústica Aplicada y Evaluación No Destructiva (CAEND), UPM-CSIC, Spain Prof Francisco Montero de Espinosa, Centro de Acústica Aplicada y Evaluación No Destructiva (CAEND), UPM-CSIC, Spain Jaime Rodríguez-López, Centro de Acústica Aplicada y Evaluación No Destructiva (CAEND), UPM-CSIC, Spain Dr Carlos Sierra, Centro de Acústica Aplicada y Evaluación No Destructiva (CAEND), UPM-CSIC, Spain Shiva Kant Shukla, Centro de Acústica Aplicada y

  14. Selected Abstracts of the 2nd Congress of joint European Neonatal Societies (jENS 2017; Venice (Italy; October 31-November 4, 2017; Session "Neonatal Gastrointestinal Physiology and NEC"

    Directory of Open Access Journals (Sweden)

    --- Various Authors

    2017-10-01

    ENTEROCOLITIS • K.W. Olsson, R. SindelarABS 7. OPTICAL PROPERTIES OF EARLY STOOL FROM PRETERM INFANTS: IMPORTANT TO CONSIDER FOR ABDOMINAL OXIMETRY BASED ON NEAR-INFRARED SPECTROSCOPY • H. Isler, D. Schenk, J. Bernhard, F. Scholkmann, S. Kleiser, D. Ostojic, D. Bassler, M. Wolf, T. KarenABS 8. STOOLING PATTERN AND GASTRIC RESIDUALS ARE NOT USEFUL TOOLS FOR EARLY DIAGNOSIS OF NECROTISING ENTEROCOLITIS IN PRETERM INFANTS • S. Carlsson, M. Domellöf, A. ElfvinABS 9. REFERENCE VALUES OF ZONULIN IN TERM NEONATES • A. Tarko, A. Suchojad, A. Jarosz-Lesz, M. Majcherczyk, M. Michalec, I. Maruniak-ChudekABS 10. DETERMINANTS OF THE NEED FOR TREATMENT IN PREMATURE INFANTS WITH SUSPECTED NECROTISING ENTEROCOLITIS • N. Bussmann, A. El-Khuffash, D. CorcoranABS 11. EFFECT OF ANTIBIOTIC PROPHYLAXIS DURING REMOVAL OF A CENTRAL VENOUS CATHETER ON DEVELOPMENT OF THE NEONATAL INTESTINAL MICROBIOTA • E. d’Haens, R. Zwittink, C. Belzer, M. Hemels, R. van Lingen, I. Renes, J. Knol, D. van Zoeren-GrobbenABS 12. NEWBORNS WITH ULTRASOUND FINDING OF GAS IN HEPATIC PORTAL VENOUS SYSTEM: ANALYSIS OF RISK FACTORS, CLINICAL AND LABORATORY FINDINGS AND DEVELOPMENT OF ALLERGY • J. Lozar Krivec, A. Nyasha Zimani, N. Zupančič, D. Paro-PanjanABS 13. NEONATAL FECAL BIOMARKERS OF NECROTIZING ENTEROCOLITIS • I. Tofé, M.V. Rodriguez-Benitez, C. Hernandez-Chirlaque, M. Gil-Campos, M.D. Ruiz-Gonzalez, A. MartinezABS 14. THE OPEN ABDOMEN: A CHALLENGE FOR NEONATOLOGISTS AND NEONATAL SURGEONS. THE KAROLINSKA EXPERIENCE • M. Bartocci, E. Palleri, A. Svenningsson, T. WesterABS 15. ANOGENITAL STIMULATION IN RATS DOES NOT INCREASE GASTRIC EMPTYING • C.H. Ferreira, J. BelikABS 16. THE PRETERM INFANT GASTRIC EMPTYING RATE IS DEPENDENT ON THE FEED VOLUME AND NOT ON POSTNATAL AGE • C.H. Ferreira, F.E. Martinez, G.C. Crott, J. BelikABS 17. NECROTIZING ENTEROCOLITIS IN A NEONATAL INTENSIVE CARE UNIT • M. Branco, I. Falcão, T. Lopes, E. Proença, A. Almeida, C. Carvalho, L. PinhoABS 18. SPONTANEOUS

  15. Survival of the lichen model system Circinaria gyrosa before flight to the ISS (EXPOSE R2 mission)

    Science.gov (United States)

    De la Torre Noetzel, Rosa

    potential to space and Mars conditions, contributing to our understanding of extremotolerance and the Lithopanspermia hypothesis [7]. References [1] Rabbow, E., und Rettberg, Petra und Barczyk, Simon und Bohmeier, Maria und Parpart, André und Panitz, Corinna und Horneck, Gerda und von Heise-Rotenburg, Ralf und Hoppenbrouwers, Tom und Willnecker, Rainer und Baglioni, Pietro und Demets, René und Dettmann, Jan und Reitz, Guenther (2012) EXPOSE-E: An ESA Astrobiology Mission 1.5 Years in Space. Astrobiology, 12 (5), Seiten 374-386. Mary Ann Liebert, Inc.. DOI: 10.1089/ast.2011.0760. [2] De la Torre, R. L.G. Sancho, G. Horneck, A.de los Ríos, J. Wierzchos, K. Olsson-Francis, C.S. Cockell, Rettberg P., T. Berger, J.P. de Vera, S. Ott, J. Martinez Frías, P.Gonzalez Melendi M.M. Lucas, M. Reina, A. Pintado, R.Demets. Survival of lichens and bacteria exposed to outer space conditions. Results of the Lithopanspermia experiments. Icarus, doi:10.1016/j.icarus.2010.03.010 (2010). [3] Sanchez, F.J., E. Mateo-Martí, J. Raggio, J. Meessen, J. Martinez-Frias, L. Gª Sancho, S. Ott and R. de la Torre. The resistance of the lichen Circinaria gyrosa (nom. provis.) towards simulated Mars conditions - a model test for the survival capacity of an eukaryotic extremophyle. Planetary and Space Science 72, 102-110 (2012). [4] de Vera JP and the BIOMEX-Team (2012) Supporting Mars exploration: BIOMEX in Low Earth Orbit and further astrobiological studies on the Moon using Raman and PanCam technology. Planetary and Space Science, 74 (1), Seiten 103-110. Elsevier. DOI:10.1016/j.pss.2012.06.010. [5] Meeßen J, Sánchez FJ, Brandt A, Balzer EM, de la Torre R, Sancho LG, de Vera JP, Ott S (2013) Extremotolerance and resistance of lichens: Comparative studies on five species used in astrobiological research I. Morphological and anatomical characteristics. Origins of Life and Evolution of Biospheres 43 (3): 283-303 [6] Meeßen J, Sánchez FJ, Sadowsky A, de Vera JP, de la Torre R, Ott S (2013

  16. Methods of geodiversity assessment and theirs application

    Science.gov (United States)

    Zwoliński, Zbigniew; Najwer, Alicja; Giardino, Marco

    2016-04-01

    The concept of geodiversity has rapidly gained the approval of scientists around the world (Wiedenbein 1993, Sharples 1993, Kiernan 1995, 1996, Dixon 1996, Eberhard 1997, Kostrzewski 1998, 2011, Gray 2004, 2008, 2013, Zwoliński 2004, Serrano, Ruiz- Flano 2007, Gordon et al. 2012). However, the problem recognition is still at an early stage, and in effect not explicitly understood and defined (Najwer, Zwoliński 2014). Nevertheless, despite widespread use of the concept, little progress has been made in its assessment and mapping. Less than the last decade can be observing investigation of methods for geodiversity assessment and its visualisation. Though, many have acknowledged the importance of geodiversity evaluation (Kozłowski 2004, Gray 2004, Reynard, Panizza 2005, Zouros 2007, Pereira et al. 2007, Hjort et al. 2015). Hitherto, only a few authors have undertaken that kind of methodological issues. Geodiversity maps are being created for a variety of purposes and therefore their methods are quite manifold. In the literature exists some examples of the geodiversity maps applications for the geotourism purpose, basing mainly on the geological diversity, in order to point the scale of the area's tourist attractiveness (Zwoliński 2010, Serrano and Gonzalez Trueba 2011, Zwoliński and Stachowiak 2012). In some studies, geodiversity maps were created and applied to investigate the spatial or genetic relationships with the richness of particular natural environmental components (Burnett et al. 1998, Silva 2004, Jačková, Romportl 2008, Hjort et al. 2012, 2015, Mazurek et al. 2015, Najwer et al. 2014). There are also a few examples of geodiversity assessment in order to geoconservation and efficient management and planning of the natural protected areas (Serrano and Gonzalez Trueba 2011, Pellitero et al. 2011, 2014, Jaskulska et al. 2013, Melelli 2014, Martinez-Grana et al. 2015). The most popular method of assessing the diversity of abiotic components of the natural

  17. Tõlkepoeetikast teksti ja keele taustal / On the Poetics of Translation

    Directory of Open Access Journals (Sweden)

    Anne Lange

    2016-01-01

    In order to illustrate the practical implications of this approach, the article highlights translational solutions that cannot be explained in linguistic terms given that they attempt to maintain the specifics of the original. The translator proceeds by pretending to know what a text (and its author is doing; it is the cognitive filter of the translator that gives the source text its meaning. In an account of her translation of Jaan Malin’s ”Keele meel“ into English, Miriam McIlfatrick-Ksenofontov begins with the analysis of the poem. This entails separating the whole into its component parts and identifying their relations. Reading with a view to translating unravels the texture of a poem, exposing the lexical, semantic and phonetic strands that constitute its coherence. The article then offers an account of how the translator experiences the original and navigates through it towards a new poem in translation, recognising that languages differ in what they can and must do. The latter, primarily a grammatical reality, is accompanied by a semantic one: the implications that stem from lexical connotations are inevitably different in the original poem and in the new poem. However, the supposed intent of the original is what a cognitive approach sees as a possibility of translation. This does not involve the transferral of isolated lexicalised items, but allows the translator to overcome the dilemma of retaining both form and content by adopting the role of writer, by working with language that is at no more at her disposal than it is for the writer of the original. The analysis of the original enables the translator to avoid seeing the poem as fixed language in a solid object or searching for a single invariant meaning. Between the reader and the poem a situation of dialogue is established that involves asking questions of the poem in order to find what meanings it insists on. Questions like what does this word (image, rhyme, comma, etc. do in/to the poem? how

  18. Book Reviews

    Directory of Open Access Journals (Sweden)

    H.J.M. Claessen

    1990-04-01

    , Bernard Juillerat, Les enfants du sang: Société, reproduction et imaginaire en Nouvelle-Guinée, Paris: Editions de la Maison des Sciences de l’Homme, 1986, 569 pp. - M.A. Kagenaar, Aart G. Broek, Het Zilt van de Passaten; Caribische Letteren van Verzet; Essays. Haarlem: In de Knipscheer, 1988; 186 pp. - Peter Meel, Ben Scholtens, Louis Doedel, Surinaams vakbondsleider van het eerste uur; Een bronnenpublikatie. Paramaribo: Anton de Kom Universiteit van Suriname. 1987. 141 p. - Peter Meel, Nico Wijnen et al., A. de Kom, zijn strijd en ideeën, Amsterdam: Sranan Buku, 1989. 130 pp. - D.C. Mulder, A.A. Yewangoe, Theologia Crucis in Asia, Amsterdam, 1987. 352 pp. - Rien Ploeg, H.J.M. Claessen, Bronnen van macht; Over het gebruik van bronnen in het onderzoek naar de vroege staat, Leiden: ICA, 1987. 159 pp., J.G. Oosten (eds. - Rien Ploeg, H.J.M. Claessen, Over de politiek denkende en handelende mens; Een inleiding in de politieke antropologie, Assen/Maastricht: Van Gorcum, 1988. 168 pp. - Harry A. Poeze, L.F. Jansen, In deze halve gevangenis; Dagboek van mr dr L.F. Jansen, Batavia/Djakarta 1942-1945; Bezorgd en geannoteerd door G.J. Knaap. Franeker: Van Wijnen, 1988, liv + 447 p. - Franois Raillon, William H. Frederick, Visions and heat; The making of the Indonesian revolution, Athens: Ohio University Press, 1989. 339 pp. - Reimar Schefold, Barbara Lüem, Wir sind wie der Berg, lächelnd aber stark: Eine studie zur ethnischen indentität der Tenggeresen in Ostjava, Basel: Ethnologisches Seminar der Universität und Museum für Völkerkunde. Distributed by Wepf & Co. AG Verlag, 1988, 243 pp.; ill. - J.W. Schoorl, J. van Baal, Ontglipt verleden; Verhaal van mijn jaren in een wereld die voorbijging, deel I, Tot 1947: Indisch bestuursambtenaar in vrede en oorlog; deel II, Leven in verandering: 1947-1958, Franeker: Wever. 1986, 510 pp., resp. 1989, 616 pp. - I. Serpenti, Miriam Kahn, Always hungry - Never greedy; Food and the expression of gender in a Melanesian society

  19. Obituary: Maurice M. Shapiro, 1915-2008

    Science.gov (United States)

    Yodh, Gaurang B.

    2009-01-01

    Maurice Shapiro was an outstanding scientist and educator whose contributions spanned a range of fields: He was the leader of the "Water Effects" group (study of underwater explosions) within the Los Alamos Ordnance Division in the Manhattan project during World War II; he witnessed the Trinity test and there "shared a blanket with Hans Bethe." Shapiro understood the nature of the new weapons and helped to form the Association of Los Alamos Scientists [ALAS] to lobby for a civilian atomic-energy commission. (He was chair of ALAS in 1946.) He also worked at Oak Ridge on design of a power reactor just after the war (similar to those used in naval vessels). In 1949 Shapiro joined the Naval Research Laboratory's nuclear physics division, where he started a new program in high-energy physics and cosmic rays, his primary interest throughout his life. In 1977, he founded the International School of Cosmic-Ray Astrophysics in Erice, Italy, where many outstanding scientists in the field were students at early stages of their career. He served as director of this school until his death. Shapiro was interested in understanding the origin, acceleration, and propagation of cosmic rays and the role of high energy neutrinos and their detection. He played a major role in starting the field of high-energy neutrino astronomy. Maury, so of J. Simon Werner and Miriam Rivka, was born in Jerusalem on 13 November 1915. His father never returned home from World War I, and his mother married Rabbi Osher Shapiro two years later. The family migrated to Chicago, Illinois, during the early 1920s. Maury's given name was Moishe Mendel Werner. The only father he knew was Rabbi Shapiro, hence the origin of the name we know him by. His parents had planned a theological career for him; however, Maury opted for the study of Physics at the University of Chicago. He did his Ph.D. with Arthur Compton (1942) using early emulsions exposed at Mount Evans--both emulsions on glass plates and stripped

  20. Northern California CO2 Reduction Project

    Energy Technology Data Exchange (ETDEWEB)

    Hymes, Edward [C6 Resources LLC, Houston, TX (United States)

    2010-06-16

    C6 Resources LLC, a wholly owned subsidiary of Shell Oil Company, worked with the US Department of Energy (DOE) under a Cooperative Agreement to develop the Northern California CO2 Reduction Project. The objective of the Project is to demonstrate the viability of using Carbon Capture and Sequestration (CCS) to reduce existing greenhouse gas emissions from industrial sources on a large-scale. The Project will capture more than 700,000 metric tonnes of CO2 per year, which is currently being vented to the atmosphere from the Shell Martinez Refinery in Contra Costa County. The CO2 will be compressed and dehydrated at the refinery and then transported via pipeline to a sequestration site in a rural area in neighboring Solano County. The CO2 will be sequestered into a deep saline formation (more than two miles underground) and will be monitored to assure secure, long-term containment. The pipeline will be designed to carry as much as 1,400,000 metric tonnes of CO2 per year, so additional capacity will be available to accommodate CO2 captured from other industrial sources. The Project is expected to begin operation in 2015. The Project has two distinct phases. The overall objective of Phase 1 was to develop a fully definitive design basis for the Project. The Cooperative Agreement with the DOE provided cost sharing for Phase 1 and the opportunity to apply for additional DOE cost sharing for Phase 2, comprising the design, construction and operation of the Project. Phase 1 has been completed. DOE co-funding is provided by the American Recovery and Reinvestment Act (ARRA) of 2009. As prescribed by ARRA, the Project will stimulate the local economy by creating manufacturing, transportation, construction, operations, and management jobs while addressing the need to reduce greenhouse gas emissions at an accelerated pace. The Project, which will also assist in meeting the CO2 reduction requirements set

  1. DREAMS: a payload on-board the ExoMars EDM Schiaparelli for the characterization of Martian environment during the statistical dust storm season

    Science.gov (United States)

    Molfese, Cesare; Esposito, Francesca; Debei, Stefano; Bettanini, Carlo; Arruego Rodríguez, Ignacio; Colombatti, Giacomo; Harri, Ari-Matty.; Montmessin, Franck; Wilson, Colin; Aboudan, Alessio; Mugnuolo, Raffaele; Pirrotta, Simone; Marchetti, Ernesto; Witasse, Olivier

    2015-04-01

    F. Esposito1, S. Debei2, C. Bettanini2, C. Molfese1, I. Arruego Rodríguez3, G. Colombatti2, A-M. Harri4, F. Montmessin5, C. Wilson6, A. Aboudan2, S. Abbaki5, V. Apestigue3, G. Bellucci7, J-J. Berthelier5, J. R. Brucato8, S. B. Calcutt6, F. Cortecchia1, F. Cucciarrè2, G. Di Achille1, F. Ferri2, F. Forget9, E. Friso2, M. Genzer4, P. Gilbert5, H. Haukka4, J. J. Jiménez3, S. Jiménez10, J-L. Josset11, O. Karatekin12, G. Landis13, R. Lorenz14, J. Martinez3, L. Marty1, V. Mennella1, D. Möhlmann15, D. Moirin5, R. Molinaro1, E. Palomba7, M. Patel16, J-P. Pommereau5, C.I. Popa1, S. Rafkin17, P. Rannou18, N.O. Renno19, P. Schipani1, W. Schmidt4, E. Segato2, S. Silvestro1, F. Simoes20, A. Spiga9, F. Valero21, L. Vázquez21, F. Vivat5, O. Witasse22, R. Mugnuolo23, S. Pirrotta23, E.Marchetti23 1INAF - Osservatorio Astronomico di Capodimonte, Napoli, Italy, 2CISAS - Università degli Studi di Padova, Padova, Italy, 3INTA, Spain, 4Finnish Meteorological Institute (FMI),Helsinki, Finland, 5LATMOS - CNRS/UVSQ/IPSL, France, 6Oxford University, Oxford, United Kingdom, 7INAF - Istituto di Fisica dello Spazio Interplanetario (IFSI), 8INAF-Osservatorio Astrofisico di Arcetri, 9CNRS, LMD, France, 10Universidad Politécnica de Madrid, Spain, 11Space Exploration Institute, Switzerland, 12Royal Observatory of Belgium,Belgium, 13NASA, GRC, USA, 14JHU Applied Physics Lab (JHU-APL), USA, 15DLR PF Leitungsbereich, Berlin, Germany, 16Open University, UK, 17SwRL, Switzerland, 18GSMA, France, 19University of Michigan, USA, 20NASA, GSFC, USA, 21Universidad Complutense de Madrid (UCM), Spain, 22ESA-ESTEC, Noordwijk, The Netherlands, 23Italian Space Agency, Italy DREAMS (Dust characterization, Risk assessment and Environment Analyzer on the Martian Surface) package is an integrated multi-sensor scientific payload dedicated to characterizing the landing site environment in dusty conditions. It will measure pressure, wind speed and direction, relative humidity, temperature, the solar irradiance

  2. Geophysical studies of the Crump Geyser known geothermal resource area, Oregon, in 1975

    Science.gov (United States)

    Plouff, Donald

    2006-01-01

    sediment thickness was estimated at 820 meters. A three-dimensional gravity model would have yielded a greater thickness. Audiomagnotelluric measurements were not made as far south as the location of the gravity low, as determined in the field, due to a lack of communication at that time. A boat was borrowed to collect gravity measurements along the edge of Crump Lake, but the attempt was curtailed by harsh, snowy weather on May 21, 1975, which shortly followed days of hot temperature. Most of the geophysical data and illustrations in Appendix 1 have been published (Gregory and Martinez, 1975; Plouff, 1975; and Plouff and Conradi, 1975), and Donald Plouff (1986) discussed a gravity interpretation of Warner Valley at the Fall 1986 American Geophysical Union meeting in San Francisco. Further interpretation of possible subsurface geologic sources of geophysical anomalies was not discussed in Appendix 1. For example, how were apparent resistivity lows (Appendix 1, figs. 3-6) centered near Crump Geyser affected by a well and other manmade electrically conductive or magnetic objects? What is the geologic significance of the 15-milligal eastward decrease across Warner Valley? The explanation that the two-dimensional gravity model (Appendix 1, fig. 14) was based on an inverse iterative method suggested by Bott (1960) was not included. Inasmuch as there was no local subsurface rock density distribution information to further constrain the gravity model, the three-dimensional methodology suggested by Plouff (1976) was not attempted. Inasmuch as the associated publication by Plouff (1975), which released the gravity data, is difficult to obtain and not in digital format, that report is reproduced in Appendix 2. Two figures of the publication are appended to the back of the text. A later formula for the theoretical value of gravity for the given latitudes at sea level (International Association of Geodesy, 1971) should be used to re-compute gravity anomalies. To merge t

  3. Quadrotor helicopter for surface hydrological measurements

    Science.gov (United States)

    Pagano, C.; Tauro, F.; Porfiri, M.; Grimaldi, S.

    2013-12-01

    compensating for changes in pitch and roll during flight. The constant orthogonality of the camera leads to minimal image distortions and, therefore, reduced post-processing for picture dewarping. The gimbal is based on a system of two closed-loop DC motors. The motors are controlled through an open source Martinez V3 brushless controller board and an MPU6050 IMU. The IMU is placed on the back of the camera to read the change in orientation during the flight. To prevent the physical acquisition of ground reference points for image rectification, low power red lasers facing the water surface are placed on each of the quadricopter arms at known distances. The pixel distance between the laser lights in images are then automatically converted to metric units. Experimental results from outdoor testing on water bodies are reported to demonstrate the feasibility of surface water monitoring through this mobile imaging platform.

  4. Putative adaptive inter-slope divergence of transposon frequency in fruit flies (Drosophila melanogaster) at "Evolution Canyon", Mount Carmel, Israel.

    Science.gov (United States)

    Beiles, Avigdor; Raz, Shmuel; Ben-Abu, Yuval; Nevo, Eviatar

    2015-10-14

    The current analysis of transposon elements (TE) in Drosophila melanogaster at Evolution Canyon, (EC), Israel, is based on data and analysis done by our collaborators (Drs. J. Gonzalez, J. Martinez and W. Makalowski, this issue). They estimated the frequencies of 28 TEs (transposon elements) in fruit flies (D. melanogaster) from the ecologically tropic, hot, and dry south-facing slope (SFS) or "African" slope (AS) of EC and compared it with the TE frequencies on the temperate-cool and humid north-facing slope (NFS) or "European" slope (ES), separated, on average, by 250 m. The flies were sampled from two stations on each slope. We received their results, including the frequencies of each TE on each slope, and the probabilities of the statistical analyses (G-tests) of each TE separately. We continued the analysis of the inter-slope differences of the frequencies of the TEs, and based our different conclusions on that analysis and on the difference between micro (=EC) and macro (2000 km.) comparisons [Gonzalez et al. 2015 doi: 10.1186/s13062-015-0075-4 ]. Our collaborators based all their conclusions on the non-significant results of each of the individual tests of the 28 TEs. We analysed also the distribution of the TE differences between the slopes, based on their results. Thirteen TEs were more frequent on the SFS, 11 were more frequent on the NFS, and four had equal frequencies. Because of the equalizing effect of the ongoing migration, only small and temporary differences between the slopes (0 - 0.06) were regarded by us as random fluctuations (drift). Three TEs were intermediate (0.08-0.09) and await additional research. The 11 TEs with large frequency differences (0.12 - 0.22) were regarded by us as putative adaptive TEs, because the equalizing power of ongoing migration will eliminate random large differences. Five of them were higher on the SFS and six were higher on the NFS. Gaps in the distribution of the differences distinguished between the large and

  5. Diversidad de coleópteros en un bosque alto andino del municipio de Santa Rosa de Viterbo (Boyacá (Diversity of coleoptera in a high forest Andean in the municipality of Santa Rosa de Viterbo (Boyacá

    Directory of Open Access Journals (Sweden)

    Humberto Bohórquez Salazar

    2016-09-01

    (ESREY. It is important to note that this is the first study of its kind in the area. A total of 270 individuals captured belonging to 17 families, 25 subfamilies, 30 tribes and 44 genera are reported; Coccinellidae being the most representative (19.3% and less representative Dryophthoridae the family (0.4% family. It is important to note that, as reported by Martinez (2005, no records of any kind of Carabidae in the municipality are, so it can be noted that the results published in this article are the first records for Santa Rosa de Viterbo. Also the review of Medina, Lopera-Toro, Vitolo & Gill (2001 on dung beetles of Colombia indicate that genera found in this study are not recorded at a higher altitude to 2,600 meters so you can report altitudinal record for Canthon and Dichotomius Finally, the article presents the results of an education process developed with children in fifth grade of an educational institution of the municipality and the hotbeds of research ESREY, a process that was designed as a strategy to promote social appropriation of present knowledge and dissemination of the results of work.

  6. 21. ATSR congress - Book of abstracts; 21eme congres de l'ATSR - Recueil des resumes

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-10-15

    This document brings together the abstracts of all presentations given at the 21. congress of the French association for radiation protection techniques and sciences (ATSR) on the topic of Radiation protection and communication (sociology and communication impact in radiation protection): 1 - radiation protection: a permanent conciliation (G. Berne, SPR Cadarache); 2 - the nuclear argument group (M. Chevalier, R. Rzekiecki, GASN); 3 - role of the technical accreditation centre for radiation protection instrumentation (CTHIR) in radiation protection (G. Bicheron, P. Franco, IPSN); 4 - genotoxicity evaluation of ionizing radiations in a population of industrial radiologists using the lymphocyte micro-nuclei test (Sari-Minodier, T. Orsiere, D. Charrier, A. Botta, Laboratory of Bio-geno-toxicology, Medicine School, Marseille - AIMT 13, Martigues); 5 - impact of iodine 131 effluents from a cancer center on the radioactivity levels of the waste water industry ( E. Desjardins, S. Laugle, J-C. Houy, Centre Eugene Marquis, Rennes); 6 - exposed areas and personnel reclassification in medical establishments (S. Laugle, J-C. Houy, Centre Eugene Marquis, Rennes); 7 - 2SNM - a tool used by the navy for the real-time monitoring of its nuclear facilities (Y. Baron, Navy Military Staff); 8 - Intervention of the Army health service in case of radio-biological-type accident during peacetime (P.M. Curet, M. Croq, Armies Radiobiological Protection Service); 9 - the first aid chain in case of nuclear accident (L. Jorda, fire and safety Services of Bouches-du-Rhone; P. Rigaud, Central group, technological risks unit); 10 - Initiation to radioactivity in seventh grade classes of schools (G. Goulin (physics teacher, college Mignet Aix-en-Provence; J-C. Blanc, G. Juste, ATSR); 11 - communication for young people (H. Bernard, M. Gerster-Martinez, CEA-Cadarache); 12 - major risks, preventive information at Aix-en-Provence (P. Lespinat (Aix-en-Provence city security unit); 13 - scientific

  7. Neutrino oscillation parameter sampling with MonteCUBES

    Science.gov (United States)

    Blennow, Mattias; Fernandez-Martinez, Enrique

    2010-01-01

    used in GLoBES [1,2]. Solution method: MonteCUBES is written as a plug-in to the GLoBES software [1,2] and provides the necessary methods to perform Markov Chain Monte Carlo sampling of the parameter space. This allows an efficient sampling of the parameter space and has a complexity which does not grow exponentially with the parameter space dimension. The integration of the MonteCUBES package with the GLoBES software makes sure that the experimental definitions already in use by the community can also be used with MonteCUBES, while also lowering the learning threshold for users who already know GLoBES. Additional comments: A Matlab GUI for interpretation of results is included in the distribution. Running time: The typical running time varies depending on the dimensionality of the parameter space, the complexity of the experiment, and how well the parameter space should be sampled. The running time for our simulations [3] with 15 free parameters at a Neutrino Factory with O(10) samples varied from a few hours to tens of hours. References:P. Huber, M. Lindner, W. Winter, Comput. Phys. Comm. 167 (2005) 195, hep-ph/0407333. P. Huber, J. Kopp, M. Lindner, M. Rolinec, W. Winter, Comput. Phys. Comm. 177 (2007) 432, hep-ph/0701187. S. Antusch, M. Blennow, E. Fernandez-Martinez, J. Lopez-Pavon, arXiv:0903.3986 [hep-ph].

  8. Acid Evolution of Escherichia coli K-12 Eliminates Amino Acid Decarboxylases and Reregulates Catabolism.

    Science.gov (United States)

    He, Amanda; Penix, Stephanie R; Basting, Preston J; Griffith, Jessie M; Creamer, Kaitlin E; Camperchioli, Dominic; Clark, Michelle W; Gonzales, Alexandra S; Chávez Erazo, Jorge Sebastian; George, Nadja S; Bhagwat, Arvind A; Slonczewski, Joan L

    2017-06-15

    Acid-adapted strains of Escherichia coli K-12 W3110 were obtained by serial culture in medium buffered at pH 4.6 (M. M. Harden, A. He, K. Creamer, M. W. Clark, I. Hamdallah, K. A. Martinez, R. L. Kresslein, S. P. Bush, and J. L. Slonczewski, Appl Environ Microbiol 81:1932-1941, 2015, https://doi.org/10.1128/AEM.03494-14). Revised genomic analysis of these strains revealed insertion sequence (IS)-driven insertions and deletions that knocked out regulators CadC (acid induction of lysine decarboxylase), GadX (acid induction of glutamate decarboxylase), and FNR (anaerobic regulator). Each acid-evolved strain showed loss of one or more amino acid decarboxylase systems, which normally help neutralize external acid (pH 5 to 6) and increase survival in extreme acid (pH 2). Strains from populations B11, H9, and F11 had an IS 5 insertion or IS-mediated deletion in cadC , while population B11 had a point mutation affecting the arginine activator adiY The cadC and adiY mutants failed to neutralize acid in the presence of exogenous lysine or arginine. In strain B11-1, reversion of an rpoC (RNA polymerase) mutation partly restored arginine-dependent neutralization. All eight strains showed deletion or downregulation of the Gad acid fitness island. Strains with the Gad deletion lost the ability to produce GABA (gamma-aminobutyric acid) and failed to survive extreme acid. Transcriptome sequencing (RNA-seq) of strain B11-1 showed upregulated genes for catabolism of diverse substrates but downregulated acid stress genes (the biofilm regulator ariR , yhiM , and Gad). Other strains showed downregulation of H 2 consumption mediated by hydrogenases ( hya and hyb ) which release acid. Strains F9-2 and F9-3 had a deletion of fnr and showed downregulation of FNR-dependent genes ( dmsABC , frdABCD , hybABO , nikABCDE , and nrfAC ). Overall, strains that had evolved in buffered acid showed loss or downregulation of systems that neutralize unbuffered acid and showed altered regulation of

  9. Teaching and learning the geological knowledge as a part of the science education general field

    Science.gov (United States)

    Aguirre-Pérez, Constancio

    2010-05-01

    space sciences" emphasizes still further such character receiving the contributions of physics, chemistry, biology and environmental science in a kind of scientific-technical mixture which enriches the discipline itself and constitutes a fundamental basis for the evolution of knowledge in its broadest sense (Martinez Frias et al. 2008). In this paper we propose to show some of the experiences and didactic innovations in the teaching of geology found in the scientific literature in recent years and likewise part of an author's own work on the establishment of analogies on the time variable based on Carl Sagan's cosmic calendar. With these analogies we try to approximate geologic times to the understanding of high school and first university courses students (Aguirre-Perez, C. 2008) REFERENCES ALIBERAS, J. GUTIÉRREZ, R. and IZQUIERDO, M. (1989). La Didáctica de las Ciencias: Una empresa racional. Enseñanza de las Ciencias, 7 (3), pp. 227-284. GUTIÉRREZ, R. (1987). Psicología y aprendizaje de las Ciencias. El modelo de Ausubel. Enseñanza de las Ciencias, 5 (2), pp. 118-128. MARTÍNEZ FRÍAS, J. LUNAR, R. RODRÍGUEZ-LOSADA, J.A. EFF-DARWICH, A. and MADERO JARABO, J. (2008)"La Geología en la exploración planetaria (Geology inplanetary exploration). Geo-temas 10, pp. 1621-1624. PEDRINACI, E. (2000): La Enseñanza y el aprendizaje del conocimiento geológico. Didáctica de las Ciencias Experimentales. Teoría y Práctica de la Enseñanza de las ciencias, pp. 479-503. Ed. Marfil.

  10. Predicting high risk of exacerbations in bronchiectasis: the E-FACED score

    Directory of Open Access Journals (Sweden)

    Martinez-Garcia MA

    2017-01-01

    Full Text Available Martinez-Garcia MA,1,2 Athanazio RA,3 Girón R,4 Máiz-Carro L,5 de la Rosa D,6 Olveira C,7 de Gracia J,2,8 Vendrell M,9 Prados-Sánchez C,10 Gramblicka G,11 Corso Pereira M,12 Lundgren FL,13 Fernandes De Figueiredo M,14 Arancibia F,15 Rached SZ3 1Pulmonary Service, Polytechnic and University La Fe Hospital, Valencia, Spain; 2CIBERes, CIBER de Enfermedades Respiratorias. Madrid. Spain; 3Pulmonary Division, Heart Institute (Incor, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo; 4Pneumology Service, Hospital La Princesa, 5Pneumology Service, Hospital Ramón y Cajal, Madrid, 6Pneumology Unit, Hospital Plató, Barcelona, 7Pneumology, Málaga Regional University Hospital, Instituto de Biomedicina de Málaga (IBIMA, Málaga University, Spain; 8Pneumology Service, Hospital Vall d’Hebron, Barcelona, 9Bronchiectasis Group IDIBGI, Dr. Trueta University Hospital. UdG. Ciberes CB06/06/0030, 10Unidad de Fibrosis Quística y Bronquiectasias. Hospital Universitario La Paz. Madrid. Spain; 11Pneumology Service, Hospital del Tórax Dr A Cetrángolo, Buenos Aires, Argentina; 12Pneumology Service, Universidade Estadual de Campinas UNICAMP, Sao Paulo, 13Pneumology Service, Hospital Octávio de Freitas, Recife, 14Pneumology Service, Hospital de Messejana, Fortaleza, Brazil; 15Pneumology Service, Instituto Nacional del Tórax, Santiago de Chile, Chile Background: Although the FACED score has demonstrated a great prognostic capacity in bronchiectasis, it does not include the number or severity of exacerbations as a separate variable, which is important in the natural history of these patients.Objective: Construction and external validation of a new index, the E-FACED, to evaluate the predictive capacity of exacerbations and mortality.Methods: The new score was constructed on the basis of the complete cohort for the construction of the original FACED score, while the external validation was undertaken with six cohorts from three

  11. Controlling factors of nitrous oxide (N2O) emissions at the field-scale in an agricultural slope

    Science.gov (United States)

    Vilain, Guillaume; Garnier, Josette; Tallec, Gaëlle; Tournebize, Julien; Cellier, Pierre; Flipo, Nicolas

    2010-05-01

    short period of one month. Landscape position strongly affected cumulative N2O emissions which were more than three times higher in footslope position (annual budget of 4 kg N-N2O ha-1 yr-1) than in shoulder (1.1 kg N-N2O ha-1 yr-1) or slope positions (1.1 and 1.2 kg N-N2O ha-1 yr-1), where soil water contents were higher (mean 68.4% WFPS in footslope position whereas mean WFPS were 50.4 and 60.5% in slope positions and 58% in shoulder position). N2O emissions were relatively low (0.5 kg N-N2O ha-1 yr-1) and did not show much annual variation in unfertilized riparian buffer. Garnier, J., Billen, G., Vilain, G., Martinez, A., Silvestre, M., Mounier, E., & Toche, F., 2009. Nitrous oxide (N2O) in the Seine river and basin: Observations and budgets. Agriculture, Ecosystems & Environment 133, 223-233. IPCC, 2007. Climate change 2007: the physical science basis. Summary for Policy Makers, Contribution of Working Group I to the Fourth Assessment Report of the Intergovernmental Panel on Climate Change. Izaurralde, R. C., Lemke, R. L., Goddard, T. W., McConkey, B., & Zhang, Z., 2004. Nitrous Oxide Emissions from Agricultural Toposequences in Alberta and Saskatchewan. Soil Sci Soc Am J 68, 1285-1294.

  12. Evolution of Cognitive Rehabilitation After Stroke From Traditional Techniques to Smart and Personalized Home-Based Information and Communication Technology Systems: Literature Review.

    Science.gov (United States)

    Cogollor, José M; Rojo-Lacal, Javier; Hermsdörfer, Joachim; Ferre, Manuel; Arredondo Waldmeyer, Maria Teresa; Giachritsis, Christos; Armstrong, Alan; Breñosa Martinez, Jose Manuel; Bautista Loza, Doris Anabelle; Sebastián, José María

    2018-03-26

    the selection of 8 different ICT-based approaches found in scientific-technical studies, 9 European projects funded by the European Commission that offer eHealth architectures, and other large-scale activities such as smart houses and the initiative City4Age. Stroke is one of the main causes that most negatively affect countries in the socioeconomic aspect. The design of new ICT-based systems should provide 4 main features for an efficient and personalized cognitive rehabilitation: support in the execution of complex daily tasks, automatic error detection, home-based performance, and accessibility. Only 33% of the European projects presented fulfilled those requirements at the same time. For this reason, current and future large-scale initiatives focused on eHealth and smart environments should try to solve this situation by providing more complete and sophisticated platforms. ©José M Cogollor, Javier Rojo-Lacal, Joachim Hermsdörfer, Manuel Ferre, Maria Teresa Arredondo Waldmeyer, Christos Giachritsis, Alan Armstrong, Jose Manuel Breñosa Martinez, Doris Anabelle Bautista Loza, José María Sebastián. Originally published in JMIR Rehabilitation and Assistive Technology (http://rehab.jmir.org), 26.03.2018.

  13. Is there an association between diabetes and neck pain and lower back pain? Results of a population-based study

    Directory of Open Access Journals (Sweden)

    Jimenez-Garcia R

    2018-05-01

    Full Text Available Rodrigo Jimenez-Garcia,1 José Luis del Barrio,1 Valentín Hernandez-Barrera,1 Javier de Miguel-Díez,2 Isabel Jimenez-Trujillo,1 María Angeles Martinez-Huedo,3 Ana Lopez-de-Andres1 1Preventive Medicine and Public Health Teaching and Research Unit, Health Sciences Faculty, Universidad Rey Juan Carlos, Alcorcón, Madrid, Spain; 2Respiratory Department, Hospital General Universitario Gregorio Marañón, Facultad de Medicina, Universidad Complutense de Madrid (UCM, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM, Madrid, Spain; 3Preventive Medicine and Public Health, Unidad de Docencia, Hospital Universitario La Paz, Madrid, Spain Background: The objective of the study was to study the association between low back pain (LBP, neck pain (NP, and diabetes while controlling for many sociodemographic characteristics, comorbidities, and lifestyle variables. The study also aimed to identify which of these variables is independently associated with LBP and NP among diabetes sufferers. Methods: A case–control study using data taken from the European Health Interview Surveys for Spain was conducted in 2009/2010 (n=22,188 and 2014 (n=22,842. We selected subjects ≥40 years of age. Diabetes status was self-reported. One non-diabetic control was matched by the year of survey, age, and sex for each diabetic case. The presence of LBP and NP was defined as the affirmative answer to both of the questions: “Have you suffered chronic LBP/NP over the last 12 months?” and “Has your physician confirmed the diagnosis?” Independent variables included demographic and socioeconomic characteristics, health status variables, lifestyles, and pain characteristics. Results: The prevalence of NP (32.2% vs 26.8% and LBP (37.1% vs 30.3% was significantly higher among those suffering from diabetes. Multivariable analysis showed that diabetes was associated with a 1.19 (95% CI 1.04–1.36 and 1.20 (95% CI 1.06–1.35 higher risk of NP and LBP. Among

  14. Mitogen-activated protein kinase phosphatase-3 (MKP-3 in the surgical wound is necessary for the resolution of postoperative pain in mice

    Directory of Open Access Journals (Sweden)

    Skopelja-Gardner S

    2017-03-01

    Full Text Available Sladjana Skopelja-Gardner,1,* Madhurima Saha,1,* Perla Abigail Alvarado-Vazquez,2 Brenna S Liponis,1 Elena Martinez,1 E Alfonso Romero-Sandoval2 1Department of Anesthesiology, Geisel School of Medicine at Dartmouth, Lebanon, NH, 2Department of Pharmaceutical and Administrative Sciences, Presbyterian College School of Pharmacy, Clinton, SC, USA *These authors contributed equally to this work. Abstract: Mitogen-activated protein kinase (MAPK phosphatase-3 (MKP-3 and its substrates (extracellular signal-regulated kinase [ERK] and p38 play an important role in pathophysiological mechanisms of acute postoperative and chronic neuropathic pain in the spinal cord. This study aimed to understand the role of MKP-3 and its target MAPKs at the site of surgical incision in nociceptive behavior. Wild-type (WT and MKP-3 knockout (KO mice underwent unilateral plantar hind paw incision. Mechanical allodynia was assessed by using von Frey filaments. Peripheral ERK-1/2 and p38 phosphorylation were measured by Western blot. Cell infiltration was determined using hematoxylin and eosin histological staining. Peripheral phosphorylated ERK-1/2 (p-ERK-1/2 inhibition was performed in MKP-3 KO mice. In WT mice, mechanical hypersensitivity was observed on postoperative day 1 (0.69±0.17 g baseline vs 0.13±0.08 g day 1, which resolved normally by postoperative day 12 (0.46±0.08 g, N=6. In MKP-3 KO mice, this hypersensitivity persisted at least 12 days after surgery (0.19±0.06 g; N=6. KO mice displayed higher numbers of infiltrating cells (51.4±6 cells/0.1 mm2 than WT mice (8.7±1.2 cells/0.1 mm2 on postoperative day 1 (vs 5–6 cells/0.1 mm2 at baseline that returned to baseline 12 days after surgery (10–12 cells/0.1 mm2. In WT mice, peripheral p-p38 and p-ERK-1/2 expression increased (5- and 3-fold, respectively on postoperative days 1 and 5, and returned to basal levels 7–12 days after surgery (N=3 per group. Peripheral p-p38 levels in MKP-3 KO mice followed

  15. Experts Complete IAEA Follow-up Review of Spanish Nuclear Regulatory Authority

    International Nuclear Information System (INIS)

    2011-01-01

    areas of inspection and public communication as a consequence of the lessons learned in 2008 from the event at the Asco Nuclear Power Plant; CSN's interactions at the highest level with licensees to discuss strategic planning and their investments in safety and human resources; and The establishment of formal frameworks for cooperation between the CSN and several governmental organizations, such as the Ministry of Health and the Ministry of Interior in the areas of radiation protection and security. Carmen Martinez Ten, President of CSN, said, 'I am proud that Spain is among the first countries to have received a full- scope IRRS mission and a follow-up. CSN has benefitted from the IRRS mission using the contribution from senior regulators which has resulted and will continue in further improvements in our regulatory framework.' The IRRS team also made recommendations and suggestions to further strengthen Spain's regulatory body, including: CSN should establish a formal policy on how to use technical advisory bodies for technical regulatory decisions; CSN should continue to work with relevant bodies to prepare for the disposal of spent fuel and high-level waste, taking into account the progress being made in the siting of a storage facility; and CSN should continue to work with relevant competent authorities and other bodies on regulatory aspects of security. Denis Flory, IAEA Deputy Director General for Nuclear Safety and Security, said, 'This mission is a clear example of the value of regulatory bodies participating in a senior peer review process offered by IAEA. A particularly important feature of these IRRS follow-up missions is to assess the effective implementation of the recommendations made. This mission to Spain also demonstrates clearly the mutual interest of IRRS missions: they encourage improvements in the host countries and serve as valuable sources of information for the reviewers themselves and for other regulatory bodies.' (IAEA)

  16. 21. ATSR congress - Book of abstracts

    International Nuclear Information System (INIS)

    2000-10-01

    This document brings together the abstracts of all presentations given at the 21. congress of the French association for radiation protection techniques and sciences (ATSR) on the topic of Radiation protection and communication (sociology and communication impact in radiation protection): 1 - radiation protection: a permanent conciliation (G. Berne, SPR Cadarache); 2 - the nuclear argument group (M. Chevalier, R. Rzekiecki, GASN); 3 - role of the technical accreditation centre for radiation protection instrumentation (CTHIR) in radiation protection (G. Bicheron, P. Franco, IPSN); 4 - genotoxicity evaluation of ionizing radiations in a population of industrial radiologists using the lymphocyte micro-nuclei test (Sari-Minodier, T. Orsiere, D. Charrier, A. Botta, Laboratory of Bio-geno-toxicology, Medicine School, Marseille - AIMT 13, Martigues); 5 - impact of iodine 131 effluents from a cancer center on the radioactivity levels of the waste water industry ( E. Desjardins, S. Laugle, J-C. Houy, Centre Eugene Marquis, Rennes); 6 - exposed areas and personnel reclassification in medical establishments (S. Laugle, J-C. Houy, Centre Eugene Marquis, Rennes); 7 - 2SNM - a tool used by the navy for the real-time monitoring of its nuclear facilities (Y. Baron, Navy Military Staff); 8 - Intervention of the Army health service in case of radio-biological-type accident during peacetime (P.M. Curet, M. Croq, Armies Radiobiological Protection Service); 9 - the first aid chain in case of nuclear accident (L. Jorda, fire and safety Services of Bouches-du-Rhone; P. Rigaud, Central group, technological risks unit); 10 - Initiation to radioactivity in seventh grade classes of schools (G. Goulin (physics teacher, college Mignet Aix-en-Provence; J-C. Blanc, G. Juste, ATSR); 11 - communication for young people (H. Bernard, M. Gerster-Martinez, CEA-Cadarache); 12 - major risks, preventive information at Aix-en-Provence (P. Lespinat (Aix-en-Provence city security unit); 13 - scientific

  17. Resistance of lichens to simulated galactic cosmic radiation: limits of survival capacity and biosignature detection

    Science.gov (United States)

    de la Torre Noetzel, Rosa; Miller, Ana Z.; Cubero, Beatriz; Raguse, Marina; Meessen, Joachim

    2016-04-01

    in the universe, and as contribution of lithopanspermia, the theory that supports the interplanetary transfer of rock inhabiting life by means of meteorites (Mileikovsky et al., 2000). Acknowledgements: AZ Miller acknowledges the support from the Marie Skłodowska-Curie actions (PIEF-GA-2012-328689). References Böttger U, Meessen J, Martinez-Frias J, Hübers H-W, Rull F, Sánchez FJ, de la Torre R, de Vera J-P. 2014. International Journal of Astrobiology 13: 19-27. de la Torre R, Sancho LG, Horneck G, de los Ríos A, Wierzchos J, Olsson-Francis K, et al. 2010. Icarus 208: 735-748. de los Ríos A, Wierzchos J, Sancho LG, Ascaso C. 2004. FEMS Microbiology Ecology 50: 143-152. Mileikovsky C, Cucinotta F, Wilson JW, Gladman B, Horneck G, Lindegren L, Melosh J, Rickman H, Valtonen M, Zheng JQ. 2000. Icarus 145, 391-427. Moeller R, Rohde M, Reitz G. 2010. Icarus 206: 783-786. Sánchez FJ, Mateo-Martí E, Raggio J, Meeßen J, Martínez-Frías J, Sancho LG, et al. 2012. Planetary and Space Science 72: 102-110.

  18. Evaluating the Social Media Performance of Hospitals in Spain: A Longitudinal and Comparative Study.

    Science.gov (United States)

    Martinez-Millana, Antonio; Fernandez-Llatas, Carlos; Basagoiti Bilbao, Ignacio; Traver Salcedo, Manuel; Traver Salcedo, Vicente

    2017-05-23

    showed better performance on Facebook and YouTube. The two-sided Wilcoxon test and t student test at a CI of 95% show that the use of Twitter distribution is higher (Psocial networks is still not as high compared to that of hospitals in the United States and Western Europe. Public hospitals are found to be more active on Twitter, whereas private hospitals show better performance on Facebook and YouTube. This study suggests that hospitals, both public and private, should devote more effort to and be more aware of social media, with a clear strategy as to how they can foment new relationships with patients and citizens. ©Antonio Martinez-Millana, Carlos Fernandez-Llatas, Ignacio Basagoiti Bilbao, Manuel Traver Salcedo, Vicente Traver Salcedo. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 23.05.2017.

  19. Improving the Algae Bloom Prediction through the Assimilation of the Remotely Sensed Chlorophyll-A Data in a Generic Ecological Model in the North Sea

    Science.gov (United States)

    El Serafy, Ghada

    2010-05-01

    . Blauw A.N., Los F.J., Bokhorst M., Erftemeijer P.L.A., (2009), GEM: a Generic Ecological Model for estuaries and coastal waters. Journal of Hydrobiologia, Volume 618, Number 1, 175-198. Peters, S.W.M., Eleveld, M. Pasterkamp, R., Woerd, H. van der, Devolder, M., Jans, S., Park, Y., Ruddick, K., Block, T., Brockmann, C., Doerffer, R., Krasemann, H., Röttgers, R., Schönfeld, W., Jørgensen, P.V., Tilstone, G., Martinez-Vicente, V., Moore, G., Sørensen, K., Høkedal, J., Johnsen, T.M., Lømsland, E.R., Aas, E. (2005). Atlas of Chlorophyll-a concentration for the North Sea based on MERIS imagery of 2003. IVM report, Vrije Universiteit Amsterdam, 117 pp. ISBN 90-5192-026-1. Salacinska K., El Serafy G.Y., Blauw A., Los F.J., (2009) Sensitivity analysis of the two dimensional application of the Generic Ecological Model (GEM) to algal bloom prediction in the North Sea, Journal of Ecological Modeling, volume 221, 7, pp 178-190, DOI: 10.1016/j.ecolmodel.2009.10.001

  20. Soil Erosion Risk Map based on irregularity of the vegetative activity

    Science.gov (United States)

    Saa-Requejo, Antonio; Tarquis, Ana Maria; Martín-Sotoca, Juan J.; Valencia, Jose L.; Gobin, Anne; Rodriguez-Sinobas, Leonor

    2016-04-01

    Because of the difficulties to build on both daily rainfall and base shorter time, we explored the possibilities of building indexes based on land cover, which also provide us the opportunity to evaluate their evolution over time. We consider the Fournier index (Fournier, 1960) which is used to assess the rainfall erosivity based on monthly rainfall, alternatively to use of the rainfall intensity in time bases under one hour (eg., van der Knijff et al., 1999; Shamshad et al, 2008). This index can also be interpreted as an index of irregularity and representing a ratio between maximum monthly precipitation and annual rainfall. We propose to calculate this irregularity in terms of irregularity of the vegetative activity. This activity is related to precipitation, but also with the availability of water in the soil reservoir and land use. Therefore, we propose a kind of Fournier index on the effective use of water, which is also closely related to variations in infiltration. Higher is the presence of vegetation higher is the effective use of water. For this "modified Fourier index" we used the NDVI (Normalized Difference Vegetation Index) as index of available vegetative activity, which is widely reported in the literature (Jensen, 2000). Initial calculations have been done with MODIS 500 x 500 m satellite data. The selected area was Cega-Eresma-Adaja subbasin during the period from 2009 to 2012. We selected 8 days composite images product. The calculation of the valid values to eliminate areas with clouds or snow is performed according to the criteria of Martinez Sotoca (2014), ie with a Saturation (based on HSL color model) greater or equal to 0.15. Then, an average of these values was estimated to represent each month of the year. The results are very interesting when we compare Modified Fournier Index on NDVIs with the map of potential soil loss. We have found surprisingly similar patterns and practical equivalence between several classes. Therefore, the Modified

  1. Chilean Teachers Begin Exchange Program Visit in Magdalena

    Science.gov (United States)

    2007-01-01

    Two teachers from the town of San Pedro de Atacama, in the northern desert of the South American nation of Chile, arrive in Magdalena, New Mexico, Sunday, January 28, for a two-week visit that is part of a Sister Cities program sponsored by Associated Universities, Inc. (AUI), the nonprofit research corporation that operates the National Radio Astronomy Observatory (NRAO). They will be accompanied by their town's mayor. Myriam Nancy Rivera Mercado, Head of the high school in San Pedro, Gabriela Fernanda Rodriguez Moraleda, a tourism teacher there, and San Pedro Mayor Sandra Berna Martinez will begin a visit that includes classroom observations in the Magdalena schools, a reception hosted by the Magdalena Village Council, and a Mayor's Breakfast with Magdalena Mayor Jim Wolfe. They also will meet local residents, tour the Bosque del Apache National Wildlife Refuge with a second-grade class, visit an area ranch, tour the Very Large Array (VLA) radio telescope, and see Socorro's Community Arts Party. "These teachers will learn much about New Mexico, the United States, and our educational system, and will take this new knowledge back to their students and their community," said NRAO Education Officer Robyn Harrison. The visit is part of a Sister Cities program initiated and funded by AUI, which operates the NRAO for the U.S. National Science Foundation. Radio astronomy is a common link between San Pedro de Atacama and Magdalena. San Pedro is near the site of the Atacama Large Millimeter/submillimeter Array (ALMA), an international telescope project now under construction with funding by major partners in North America, Europe, and Japan. Magdalena is near the site of NRAO's VLA radio telescope. In Magdalena, the Village Council and Mayor Wolfe formalized their participation in the Sister Cities program last September, and San Pedro ratified the program in December. In San Pedro, the ceremony ratifying the agreement was attended by U.S. Ambassador to Chile Craig K

  2. N-P-K balance in a milk production system on a C. nlemfuensis grassland and a biomass bank of P. purpureum CT-115 clone

    Science.gov (United States)

    Crespo, G.; Rodriguez, I.; Martinez, O.

    2009-04-01

    results agree with those reported by Jarvis (1993) and Cadish et al (1994). However, 40% of the excretions occurred in the shade buildings and milking parlours ant thus these nutrients did not recycle in the system. An important internal recycling mechanism, especially for nitrogen and potassium, is their remobilization by the rejected pasture to re-use them for the regrowth activity. This is of particular interest in CT-115 Bank, since stems of CT-115 plants left after grazing remobilize an important amount of these nutrients, guarantee a favourable pasture regrowth (Martinez 1996). The return of all the excretion to the grassland is recommended as well as increasing the area of legumes to attain a satisfactory balance of N, P and K in the system. Further studies must consider maintenance fertilization, nutrient losses due to leaching and denitrification, as well as variation of the stable OM in the soil and the influence of hydro physical properties in the recycling process. The "Recycling" software was effective to determine the balance of nutrients in the dairy farm. Cadish, G., Schunke, R.N & Giller, K.E. 1994. Nitrogen cycling in a pure grass pasture and a grass-legume mixture on a red latosol in Brazil. Tropical Grasslands 28:43. Crespo G. y Rodríguez, I. 2006. Contribución al conocimiento del reciclaje de los nutrientes en el sistema suelo-pasto-animal. Instituto de Ciencia Animal, Editorial EDICA, La Habana, Cuba, 94 pp. Hirata, M., Sugimoto, Y.G & Ueno, M.1991. Use of a mathematical model to evaluate the effects of dung from grazing animals on pasture production. J. Japan Grassld. Sci. 37:303.

  3. Psychiatrists’ awareness of adherence to antipsychotic medication in patients with schizophrenia: results from a survey conducted across Europe, the Middle East, and Africa

    Directory of Open Access Journals (Sweden)

    Olivares JM

    2013-01-01

    Full Text Available José Manuel Olivares,1 Köksal Alptekin,2 Jean-Michel Azorin,3 Fernando Cañas,4 Vincent Dubois,5 Robin Emsley,6 Philip Gorwood,7 Peter M Haddad,8 Dieter Naber,9 George Papageorgiou,10 Miquel Roca,11 Pierre Thomas,12 Guadalupe Martinez,13 Andreas Schreiner141Department of Psychiatry, Hospital Meixoeiro, Complejo Hospitalario Universitario de Vigo, Vigo, Spain; 2Department of Psychiatry, Dokuz Eylül University School of Medicine, Izmir, Turkey; 3Department of Psychiatry, Sainte Marguerite Hospital, Marseille, France; 4Department of Psychiatry, Hospital Dr R Lafora, Madrid, Spain; 5Cliniques Universitaires St-Luc, Bruxelles, Belgium; 6Department of Psychiatry, Faculty of Health Sciences, University of Stellenbosch, Cape Town, South Africa; 7Sainte-Anne Hospital, Paris Descartes University and INSERM U894, Paris, France; 8Greater Manchester West Mental Health National Health Service Foundation Trust and Department of Psychiatry, University of Manchester, Manchester, UK; 9Universitätsklinikum Hamburg-Eppendorf, Klinik für Psychiatrie und Psychotherapie, Hamburg, Germany; 10Department of Psychiatry, Evangelismos General Hospital, Athens, Greece; 11Unidad de Psiquiatría, Hospital Juan March, Institut Universitari d’Investigació en Ciències de la Salut, Universitat de les Illes Balears, Palma de Mallorca, Spain; 12Department of Psychiatry, Fontan Hospital CHRU Lille, UDSL, University North of France, Lille, France; 13Medical Affairs, Janssen, Madrid, Spain; 14Medical Affairs, Janssen, Neuss, GermanyBackground: Nonadherence is common among patients with schizophrenia, although the rates vary according to means of assessment and patient population. Failure to adhere to medication can have a major impact on the course of illness and treatment outcomes, including increasing the risk of relapse and rehospitalization. Understanding psychiatrists’ perception of the causes and consequences of nonadherence is crucial to addressing adherence problems

  4. A la costa de Luis A. Martínez: ¿la defensa de un proyecto liberal para Ecuador?

    Directory of Open Access Journals (Sweden)

    1998-01-01

    Full Text Available A LA COSTA DE LUIS A. MARTINEZ : LA DEFENSE D’UN PROJET LIBERAL POUR L’ÉQUATEUR ? A la Costa est souvent analysé comme une peinture de moeurs, témoignage de la réalité sociale et politique de l´Équateur de la fin du XIX et du début du XX. En effet, ce roman prétend décrire le conflit traditionnel qui oppose socialement, économiquement et politiquement les Andes et la Côte. Mais il se présente aussi et surtout comme la défense d´un projet libéral pour l´Équateur et développe une démonstration idéologique systématique. En outre, il propose une lecture du sens de la vie et une réflexion sur le devenir de l´homme dont la portée dépasse largement l´argumentation idéologique. Ce sont sans aucun doute ces nuances, introduites tout au long de la narration, qui permettent à l´oeuvre d´échapper à son statut exemplaire, simple témoignage d´une époque, pour proposer une vision personnelle et créative. Muchos han visto en A la Costa una novela de tendencia costumbrista, testimonio de la realidad social y política del Ecuador a finales del siglo XIX y comienzos del XX. En efecto, la novela pretende describir el conflicto tradicional social, económico, político entre Sierra y Costa. Pero es también, y ante todo, la defensa de un proyecto liberal para Ecuador, desarrollando una sistemática demostración ideológica. Además, propone una lectura del sentido de la vida y una reflexión sobre el porvenir del hombre cuyo alcance va más allá de la defensa de un proyecto ideológico. Sin duda son estos matices, introducidos a lo largo de la narración, los que permiten que la obra escape del estatuto de novela ejemplar y testimonial para proponer una visión autónoma y creativa. THE NOVEL A LA COSTA OF LUIS A. MARTÍNEZ: THE DEFENSE OF A LIBERAL PROJECT FOR ECUADOR? The novel A la Costa has often been analyzed as a portrait of national costumes, a testimony to the social and political realities of Ecuador at the end of

  5. Climate regime shifts in paleoclimate time series from the Yucatán Peninsula: from the Preclassic to Classic period

    Science.gov (United States)

    Polanco Martínez, Josue M.; Medina-Elizalde, Martin; Burns, Stephen J.; Jiang, Xiuyang; Shen, Chuan-Chou

    2015-04-01

    in precipitation. Science, 335(6071), 956-959. [6] Medina-Elizalde, M., Burns, S. J., Lea, D. W., Asmerom, Y., von Gunten, L., Polyak, V., Vuille, M., Karmalkar, A., 2010. High resolution stalagmite climate record from the Yucatán Peninsula spanning the Maya terminal classic period. Earth and Planetary Science Letters, 298(1), 255-262. [7] Medina-Elizalde, M., Burns, S. J, Jiang, X., Shen, C. C., Lases-Hernandez, F., Polanco-Martinez, J.M., High-resolution stalagmite record from the Yucatan Peninsula spanning the Preclassic period, work in progress to be submitted to the Global Planetary Change (by invitation). [8] Zeileis, A., Leisch, F., Hornik, K., Kleiber, C., 2002. strucchange: An R Package for Testing for Structural Change in Linear Regression Models. Journal of statistical software, 7(2), 1-38. [9] Mudelsee, M. (2000). Ramp function regression: a tool for quantifying climate transitions. Computers & Geosciences, 26(3), 293-307.

  6. Assessment of selected contaminants in streambed- and suspended-sediment samples collected in Bexar County, Texas, 2007-09

    Science.gov (United States)

    Wilson, Jennifer T.

    2011-01-01

    Elevated concentrations of sediment-associated contaminants are typically associated with urban areas such as San Antonio, Texas, in Bexar County, the seventh most populous city in the United States. This report describes an assessment of selected sediment-associated contaminants in samples collected in Bexar County from sites on the following streams: Medio Creek, Medina River, Elm Creek, Martinez Creek, Chupaderas Creek, Leon Creek, Salado Creek, and San Antonio River. During 2007-09, the U.S. Geological Survey periodically collected surficial streambed-sediment samples during base flow and suspended-sediment (large-volume suspended-sediment) samples from selected streams during stormwater runoff. All sediment samples were analyzed for major and trace elements and for organic compounds including halogenated organic compounds and polycyclic aromatic hydrocarbons (PAHs). Selected contaminants in streambed and suspended sediments in watersheds of the eight major streams in Bexar County were assessed by using a variety of methods—observations of occurrence and distribution, comparison to sediment-quality guidelines and data from previous studies, statistical analyses, and source indicators. Trace elements concentrations were low compared to the consensus-based sediment-quality guidelines threshold effect concentration (TEC) and probable effect concentration (PEC). Trace element concentrations were greater than the TEC in 28 percent of the samples and greater than the PEC in 1.5 percent of the samples. Chromium concentrations exceeded sediment-quality guidelines more frequently than concentrations of any other constituents analyzed in this study (greater than the TEC in 69 percent of samples and greater than the PEC in 8 percent of samples). Mean trace element concentrations generally are lower in Bexar County samples compared to concentrations in samples collected during previous studies in the Austin and Fort Worth, Texas, areas, but considering the relatively

  7. Nanocarbon: Defect Architectures and Properties

    Science.gov (United States)

    Vuong, Amanda

    V6 hexavacancy variant, where six sp3 carbon atoms sit midway between two carbon layers and bond to both, is substantially more stable than any other vacancy aggregate in AA stacked layers. Chapter 5 presents the results of ab initio DFT calculations performed to investigate the wormhole and mezzanine defect that were identified in chapter 4 and the ramp defect discovered by Trevethan et al.. DFT calculations were performed on these defects in twisted bilayer graphene. From the investigation of vacancy complexes in twisted bilayer graphene, it is found that vacancy complexes are unstable in the twisted region and are more favourable in formation energy when the stacking arrangement is close to AA or AB stacking. It has also been discovered that the ramp defect is more stable in the twisted bilayer graphene compared to the mezzanine defect. Chapter 6 presents the results of ab initio DFT calculations performed to investigate a form of extending defect, prismatic edge dislocation. Suarez-Martinez et al.'s research suggest the armchair core is disconnected from any other layer, whilst the zigzag core is connected. In the investigation here, the curvature of the mezzanine defect allows it to swing between the armchair, zigzag and Klein in the AA stacking. For the AB stacking configuration, the armchair and zigzag core are connected from any other layer. Chapter 7 present results of MD simulations using the adaptive intermolecular reactive empirical bond order (AIREBO) potential to investigate the dimensional change of graphite due to the formation of vacancies present in a single crystal. It has been identified that there is an expansion along the c-axis, whilst a contraction along the a- and b- axes due to the coalescence of vacancy forming in-plane and between the layers. The results here are in good agreement with experimental studies of low temperature irradiation. The final chapter gives conclusions to this work.

  8. De-Inventory Plan for Transuranic Waste Stored at Area G

    Energy Technology Data Exchange (ETDEWEB)

    Hargis, Kenneth Marshall [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Christensen, Davis V. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Shepard, Mark D. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-06-21

    This report describes the strategy and detailed work plan developed by Los Alamos National Laboratory (LANL) to disposition transuranic (TRU) waste stored at its Area G radioactive waste storage site. The focus at this time is on disposition of 3,706 m3 of TRU waste stored above grade by June 30, 2014, which is one of the commitments within the Framework Agreement: Realignment of Environmental Priorities between the Department of Energy (DOE) National Nuclear Security Administration (NNSA) and the State of New Mexico Environment Department (NMED), Reference 1. A detailed project management schedule has been developed to manage this work and better ensure that all required activities are aligned and integrated. The schedule was developed in conjunction with personnel from the NNSA Los Alamos Site Office (LASO), the DOE Carlsbad Field Office (CBFO), the Central Characterization Project (CCP), and Los Alamos National Security, LLC (LANS). A detailed project management schedule for the remainder of the above grade inventory and the below grade inventory will be developed and incorporated into the De-Inventory Plan by December 31, 2012. This schedule will also include all newly-generated TRU waste received at Area G in FYs 2012 and 2013, which must be removed by no later than December 31, 2014, under the Framework Agreement. The TRU waste stored above grade at Area G is considered to be one of the highest nuclear safety risks at LANL, and the Defense Nuclear Facility Safety Board has expressed concern for the radioactive material at risk (MAR) contained within the above grade TRU waste inventory and has formally requested that DOE reduce the MAR. A large wildfire called the Las Conchas Fire burned extensive areas west of LANL in late June and July 2011. Although there was minimal to no impact by the fire to LANL, the fire heightened public concern and news media attention on TRU waste storage at Area G. After the fire, New Mexico Governor Susana Martinez also

  9. Obituary: Edwin E. Salpeter (1924-2008)

    Science.gov (United States)

    Trimble, Virginia; Terzian, Yervant

    2009-12-01

    Edwin E. Salpeter, who died 26 November 2008 at his home in Ithaca, NY, belonged to the "second wave" of Jewish scientific refugees from Nazi-dominated Europe, those who left as children just before the onset of WWII and so completed their educations elsewhere. Salpeter was born in Vienna on 3 December 1924, and arrived with his family in Australia in 1939, his father was a physicist and a close friend of Erwin Schrodinger. In Australia, he finished high school, and he entered the University of Sydney at the early age of 16. He received his BS and MSc degrees in physics and mathematics from the University of Sydney, before moving on to a PhD from the University of Birmingham in 1948, for work with Rudolf Peierls on the electrodynamic self-energy of the electron, the first of more than 380 inventoried publications. He had chosen Birmingham over Cambridge or Oxford because of Peierls, and then chose Cornell over Princeton because of Hans Bethe's presence there. His autobiography describes those as two of his very best decisions ever. Marrying psychobiology student Miriam (Mika) Mark less than a year after arriving at Cornell was surely the third, and they remained in Ithaca the rest of their lives, eventually collaborating on some projects in neurobiology before her death in 2000. Their household was a secular one, but (Ed told a colleague) their two daughters received a basic Jewish education "just in case." Daughter Shelley Salpeter and her son Nicholas Buckley were also collaborators with Salpeter on 21st century projects in meta-analysis, epidemiology, and other statistics-heavy problems in biomedicine. Ed Salpeter is survived by his second wife, Antonia (Lhamo) Shouse. Astronomers may be interested to learn that the Cornell press release announcing his death was prepared by Lauren Gold, daughter of Thomas Gold (and Carrie Gold) the co-author of the steady state theory. Apparently, Ed's father Jakob Salpeter late in life considered the anisotropy reported in the

  10. Timing of Early Aptian demise of northern Tethyan carbonate platforms - chemostratigraphic versus biostratigraphic evidence

    Science.gov (United States)

    Huck, Stefan; Immenhauser, Adrian; Heimhofer, Ulrich; Rameil, Niels

    2010-05-01

    platform related to the unfolding oceanic anoxic event 1a (« Selli event »). Revue de Paléobiologie, 27, 461-468. Gradstein, F.M., Ogg, J.G., Smith, A.G., Bleeker, W. and Lourens, L.J. (2004) A new Geologic Time Scale, with special reference to Precambrian and Neogene. Episodes, 27, 83-100. Huck, S., Rameil, N., Korbar, T., Heimhofer, U., Wieczorek, T.D. and Immenhauser, A. (2010) Latitudinally different responses of Tethyan shoal-water carbonate systems to the Early Aptian oceanic anoxic event (OAE 1a). Sedimentology (pending acceptance of revised version). Moreno-Bedmar, J.A., Company, M., Bover-Arnal, T., Salas, R., Delanoy, G., Martinez, R. and Grauges, A. (2009) Biostratigraphic characterization by means of ammonoids of the lower Aptian Oceanic Anoxic Event (OAE 1a) in the eastern Iberian Chain (Maestrat Basin, eastern Spain). Cretaceous Research, 30, 864-872. Rameil, N., Immenhauser, A., Warrlich, G.M.D., Vahrenkamp, V.C., Hillgärtner, H., Droste, H.J., Al-Mahruqi, I., Buhl, D., Schulte, U. and Kunkel, C. (2009) Chemostratigraphy-based correlation of Lower Shu'aiba Formation platform sections (Early Aptian, Sultanate of Oman). In: Aptian Stratigraphy and Petroleum Habitat of the Eastern Arabian Plate (Eds F.S.P. van Buchem, M.I. Al-Husseini, F. Maurer and H.J. Droste), 4. GeoArabia Special Publication (in press), Gulf PetroLink, Bahrain. Weissert, H., Lini, A., Föllmi, K.B. and Kuhn, O. (1998) Correlation of Early Cretaceous carbon isotope stratigraphy and platform drowning events: a possible link? Palaeogeography, Palaeoclimatology, Palaeoecology, 137, 189-203.

  11. On morphology of methane-derived authigenic carbonates

    Science.gov (United States)

    Logvina, E.; Matveeva, T.

    2009-04-01

    : Northern Gulf of Mexico. Israel Journal of earth Sciences, 1994, 43, pp. 157-164. P. Jensen, I. Aagaard, R. A. Burke Jr et al. "Bubbling reefs" in the Kattegat: submarine landscapes of carbonate-cemented rocks support a diverse ecosystem at methane seeps, Mar. Ecol. Prog. Ser., 1992, 83, pp. 103-112. R.W. Botz, V. Georgiev, P. Stoffers, et al. Stable isotope study of carbonate-cemented rocks from the Pobitite Kamani area, north-eastern Bulgaria. Geologische Rundschau, 1993, 82, pp. 663- 666. V. Diaz del Rio, L. Somoza, J. Martinez-Frias, et al. Vast field of hydrocarbon-derived carbonate chimneys related to the accretionary wedge/olistostrome of the Gulf of Cadiz. Marine Geology, 2003, 195, pp.177-200. V. Magalhães, C. Vasconcelos, L. Gaspar et al. Methane related aythigenic carbonates, chimneys and crusts from the Gulf of Cadiz, Geophysical Research Abstracts, 2002, Vol. 5, 12842. W. Michaelis, R. Seifert, K. Nauhaus, T. et al. Microbial Reefs in the Black Sea Fueled by Anaerobic Oxidation of Methane. Science, 2002, 297, pp. 1013-1015.

  12. Equipe de trabalho

    Directory of Open Access Journals (Sweden)

    Gabriel Gerber Hornink

    2014-08-01

    Full Text Available   Equipe de Trabalho 2014 1. Equipe editorial Editor-Chefe Bayardo Bapstista Torres, Instituto de Química - USP, Brasil Eduardo Galembeck, Departamento de Bioquímica Instituto de Biologia UNICAMP, Brasil   Editores Gabriel Gerber Hornink, Depto. Bioquímica, Instituto de Ciências Biomédicas, Universidade - Federal de Alfenas - Unifal-MG, Brasil Vera Maria Treis Trindade, Instituto de Ciências Básicas da Saúde, Departamento de Bioquímica, Universidade Federal do Rio Grande do Sul, Brasil   Corpo Editorial Adriana Cassina, Departamento de Bioquímica, Facultad de Medicina, Universidad de la República, Uruguai Angel Herráez, Departamento de Bioquímica y Biología molecular, Universidad de Alcalá de Henares, Madrid, Espanha André Amaral Gonçalves Bianco, Universidade Federal de São Paulo (Unifesp, Brasil Denise Vaz de Macedo, Departamento de Bioquímica, Instituto de Biologia, Universidade Estadual de Campinas - Unicamp, Brasil Eneida de Paula, Departamento de Bioquímica, Instituto de Biologia, Universidade Estadual de Campinas - Unicamp, Brasil Guilherme Andrade Marson, Instituto de Química - USP, Brasil Jose Antonio Martinez Oyanedel, Universidad de Concepción, Chile Josep Maria Fernández Novell, Dept. Bioquímica i Biologia Molecular Universitat de Barcelona, Espanha Leila Maria Beltramini, Instituto de Física de São Carlos, Universidade Estadual de São Paulo - USP, Brasil Manuel João da Costa, Escola de Ciências da Saúde, Universidade do Minho, Portugal Maria Lucia Bianconi, Instituto de Bioquímica Médica Universidade Federal do Rio de Janeiro (UFRJ, Brasil María Noel Alvarez, Departamento de Bioquímica, Facultad de Medicina, Universidad de la República, Uruguai Miguel Ángel Medina Torres, Department of Molecular Biology & Biochemistry Faculty of Sciences University of Málaga, Espanha Nelma Regina Segnini Bossolan, Instituto de Física de São Carlos, Universidade de São Paulo - USP, Brasil Paulo De Avila

  13. PREFACE: IUPAP C20 Conference on Computational Physics (CCP 2011)

    Science.gov (United States)

    Troparevsky, Claudia; Stocks, George Malcolm

    2012-12-01

    . We are grateful to the committees that helped put the conference together, especially the local organizing committee. Particular thanks are also due to a number of ORNL staff who spent long hours with the administrative details. We are pleased to express our thanks to the conference administrator Ann Strange (ORNL/CDP) for her responsive and efficient day-to-day handling of this event, Sherry Samples, Assistant Conference Administrator (ORNL), Angie Beach and the ORNL Conference Office, and Shirley Shugart (ORNL) and Fern Stooksbury (ORNL) who created and maintained the conference website. Editors: G Malcolm Stocks (ORNL) and M Claudia Troparevsky (UT) http://ccp2011.ornl.gov Chair: Dr Malcolm Stocks (ORNL) Vice Chairs: Adriana Moreo (ORNL/UT) James Guberrnatis (LANL) Local Program Committee: Don Batchelor (ORNL) Jack Dongarra (UTK/ORNL) James Hack (ORNL) Robert Harrison (ORNL) Paul Kent (ORNL) Anthony Mezzacappa (ORNL) Adriana Moreo (ORNL) Witold Nazarewicz (UT) Loukas Petridis (ORNL) David Schultz (ORNL) Bill Shelton (ORNL) Claudia Troparevsky (ORNL) Mina Yoon (ORNL) International Advisory Board Members: Joan Adler (Israel Institute of Technology, Israel) Constantia Alexandrou (University of Cyprus, Cyprus) Claudia Ambrosch-Draxl (University of Leoben, Austria) Amanda Barnard (CSIRO, Australia) Peter Borcherds (University of Birmingham, UK) Klaus Cappelle (UFABC, Brazil) Giovanni Ciccotti (Università degli Studi di Roma 'La Sapienza', Italy) Nithaya Chetty (University of Pretoria, South Africa) Charlotte Froese-Fischer (NIST, US) Giulia A. Galli (University of California, Davis, US) Gillian Gehring (University of Sheffield, UK) Guang-Yu Guo (National Taiwan University, Taiwan) Sharon Hammes-Schiffer (Penn State, US) Alex Hansen (Norweigan UST) Duane D. Johnson (University of Illinois at Urbana-Champaign, US) David Landau (University of Georgia, US) Joaquin Marro (University of Granada, Spain) Richard Martin (UIUC, US) Todd Martinez (Stanford University, US) Bill

  14. Pareceristas da RBHCS no Triênio 2015-2017

    Directory of Open Access Journals (Sweden)

    Editores RBHCS

    2017-12-01

    Jonas Moreira Vargas (UFPel José Carlos da Silva Cardozo (FURG Karina Barra Gomes (UENF Lania Stefanoni Ferreira (Centro Universitário da FEI Leandro Karnal (Unicamp Leny Caselli Anzai (UFMT Luciana Mendes Gandelman (UFRRJ Luciana Rodrigues Penna (UFRGS Luciano Costa Gomes (UFRGS Luís Antonio Groppo (UNIFAL Luís Augusto Ebling Farinatti (UFSM Luisa Tombini Wittmann (UDESC Luiz Estevam de Oliveira Fernandes (UFOP Luiz Fernando Dias Duarte (Museu Nacional/ UFRJ Luiz Fernando Medeiros Rodrigues (UNISINOS Lyndon de Araújo Santos (UFMA Maíra Bonafé Sei (UEL Maísa Faleiros da Cunha (Unicamp Marcelo Henrique Nogueira Diana (IFC Marcelo Vianna (IFRS Marco Trentini (Universidad de Bologna - Itália Marcos Antonio Witt (UNISINOS Marcus Peixoto (UFRJ Maria Aparecida Bergamaschi (UFRGS Maria Cristina Bohn Martins (UNISINOS Maria de Nazaré Sarges (UFPA Maria Gabriela Silva Martins da Cunha Marinho (UFABC Mário Martins Viana Júnior (UFC Marlise Regina Meyrer (UPF Marta Regina Cioccari (UFRJ Mauro Dillmann (UFPEL Melina Piglia (Universidad Nacional de Mar del Plata - Argentina Micheli Verginia Ghiggi (UFMS Moacir de Freitas Junior (UFU Mônica da Silva Ribeiro (UFRRJ Mônica Ribeiro de Oliveira (UFJF Natália de Lacerda Gil (UFRGS Nathalia Monseff Junqueira (UFMS Nilson Gomes Vieira Filho (UFAM Patrice Schuch (UFRGS Patricia Dario El-Moor Hadjab (UNB Paulo Eduardo Teixeira (UNESP-Marília Paulo Henrique Martinez (UNESP Paulo Roberto Rodrigues Soares (UFRGS Pedro Eduardo Mesquita de Monteiro Marinho (Museu de Astronomia e Ciências Afins/UNIRIO Petrônio José Domingues (UFS Pompilio Locks Filho (UDESC Rauer Ribeiro Rodrigues (UFMS Rodrigo Stumpf González (UFRGS Roswithia Weber (FEEVALE Thiago Barcelos Soliva (UFRJ

  15. Selected Abstracts of the 6th International Congress of UENPS; Valencia (Spain; November 23rd-25th 2016; Session “Neonatology and NICU clinical care and practices”

    Directory of Open Access Journals (Sweden)

    --- Various Authors

    2016-11-01

    NEONATAL UNIT – A MULTIMODALITY APPROACH • H. Ibrahim, B. Ofoegbu, L. Yahya, K. Catroon, L. GhassaABS 13. NEONATAL DEATH NOT ARISING FROM PRETERM BIRTH IN A HIGH COMPLEXITY HEALTHCARE UNIT • A. Morillo, A. Riverola, J. Clotet, J. Silla, A. Garcia-AlixABS 14. IMPROVING EFFICIENCY AND QUALITY OF NEONATAL CLINICAL RECORDS • C. Harvey, D. LeemonABS 15. VACTERL ASSOCIATIONS: WHEN SHOULD PEDIATRICIANS THINK ABOUT THEM? • H. Chourou, F. Ayari, H. Mannai, I. Ksibi, N. Ben Ameur, M. Cheour, M. Ben Amara, S. KacemABS 16. JEUNE ASPHYXIATING THORACIC DYSTROPHY: A CASE REPORT • H. Mannai, F. Ayari, H. Chourou, I. Ksibi, N. Ben Ameur, M. Cheour, M. Ben Amara, S. KacemABS 17. PERSISTENT CLOACA IN A FEMALE NEWBORN • N. Šarlić, L. Mihovilović Prajz, J. Borošak, J. Tumbri; R. Ribičić, S. Rudman, N. Bilić, V. KošecABS 18. LATE CORD CLAMPING IN INFANTS OF DIABETIC MOTHERS • I. Vural, H. Ozdemir, A.G. Teker, A. Memisoglu, D. Save, H. Bilgen, E. OzekABS 19. STRESS BIOMARKERS IN HEALTHY PREGNANT WOMEN WITH PREVIOUS TRAUMAS • C. Cháfer-Pericás, M. Vento, P. Pacheco, A. Sanz-Bermejo, A. Redondo, D. García-Marqués, M.L. Monteagudo, M.J. Miragaya, A. García-BlancoABS 20. ASSESSING PARENTING SELF-EFFICACY BEFORE AND AFTER APPLYING A SPECIFIC TRAINING PROGRAM FOR PARENTS (CAP-PREM: PRETERM CAPACITATION DURING HOSPITALIZATION OF PRETERM NEONATES • S. Caballero, M. Arriaga, M.C. Moya, I. Echevarria, M. Martinez-Alegría, E. Cano, V. Barrera, M.S. Castillo, M. Sánchez LunaABS 21. MANAGEMENT OF ERROR DURING DRUG THERAPY • A. Portanova, F. Piersigilli, C. Auriti, N. Gioggi, G. Marrocco, P. Bagolan, A. DottaABS 22. MULTIDISCIPLINARY SIMULATION TRAININGS FOR IMPROVED MANAGEMENT OF NEONATAL EMERGENCIES • E. Saik, K. Pielberg, L. Jõgis, L. SüvariABS 23. NEONATAL MARFAN SYNDROME • T. Jurko, A. Jurko jr., A. Jurko, M. Minarik, J. Krsiakova, M. Zibolen, K. MatasovaABS 24. LONG-TERM AND SHORT-TERM EFFECTS OF PROPRANOLOL HYDROCHLORIDE TREATMENT

  16. Spatial variability of soil magnetic susceptibility in an agricultural field located in Eastern Ukraine

    Science.gov (United States)

    Menshov, Oleksandr; Pereira, Paulo; Kruglov, Oleksandr

    2015-04-01

    System Science, 11, 2285-2293. Jeleńska, M., Hasso-Agopsowicz, A., Kopcewicz, B., Sukhorada, A., Tyamina, K., Kądziałko-Hofmokl, M., Matviishina, Z. (2004) Magnetic properties of the profiles of polluted and non-polluted soils. A case study from Ukraine. Geophys. J. Int., 159, 104-116. Morton-Bernea, O., Hernandez, E., Martinez-Pichardo, E., Soler-Arechalde, A.M., Santa Cruz, R.L., Gonzalez-Hernandez, G., Beramendi-Orosco, L., Urritia-Fucugaushi, J. (2009) Mexico city topsoils: Heavy metals vs. magnetic susceptibility. Geoderma, 151, 121-125. Pereira, P., Cerdà, A., Úbeda, X., Mataix-Solera, J. Arcenegui, V., Zavala, L. Modelling the impacts of wildfire on ash thickness in a short-term period, Land Degradation and Development, (In Press), DOI: 10.1002/ldr.2195 Pereira, P., Cerdà, A., Úbeda, X., Mataix-Solera, J., Jordan, A. Burguet, M. (2013) Spatial models for monitoring the spatio-temporal evolution of ashes after fire - a case study of a burnt grassland in Lithuania, Solid Earth, 4, 153-165.

  17. Mixed Th2 and non-Th2 inflammatory pattern in the asthma–COPD overlap: a network approach

    Directory of Open Access Journals (Sweden)

    Pérez de Llano L

    2018-02-01

    Full Text Available Luis Pérez de Llano,1,* Borja G Cosío,2,3,* Amanda Iglesias,3 Natividad de las Cuevas,4 Juan Jose Soler-Cataluña,3,5 Jose Luis Izquierdo,6 Jose Luis López-Campos,3,7 Carmen Calero,7 Vicente Plaza,3,8–10 Marc Miravitlles,3,11 Alfons Torrego,8–10 Eva Martinez-Moragon,12 Joan B Soriano,13 Antolin Lopez Viña,14 Irina Bobolea15 On behalf of the CHACOS Study Group 1Department of Respiratory Medicine, Hospital Lucus Augusti, Lugo, Spain; 2Department of Respiratory Medicine, Hospital Universitario Son Espases-IdISBa, Palma de Mallorca, Spain; 3CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain; 4Department of Allergy, Hospital 12 de Octubre, Madrid, Spain; 5Department of Respiratory Medicine, Hospital Arnau de Vilanova, Valencia, Spain; 6Department of Respiratory Medicine, Hospital Universitario de Guadalajara, Guadalajara, Spain; 7Department of Respiratory Medicine, Hospital Virgen del Rocío, Sevilla, Spain; 8Department of Respiratory Medicine, Hospital de la Santa Creu y Sant Pau, Barcelona, Spain; 9Institut d’Investigació Biomédica Sant Pau, IIB Sant Pau, Barcelona, Spain; 10Department of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain; 11Department of Respiratory Medicine, Hospital Universitari Vall d’Hebron, Barcelona, Spain; 12Department of Respiratory Medicine, Hospital Dr Peset, Valencia, Spain; 13Instituto de Investigación Hospital de la Princesa, Universidad Autónoma de Madrid, Madrid, Spain; 14Department of Respiratory Medicine, Hospital Puerta de Hierro, Madrid, Spain; 15Servei de Pneumologia i Alergia, Hospital Clinic, Barcelona, Spain *These authors contributed equally to this work Introduction: The asthma–chronic obstructive pulmonary disease (COPD overlap (ACO is a clinical condition that combines features of those two diseases, and that is difficult to define due to the lack of understanding of the underlying mechanisms. Determining systemic mediators may help clarify

  18. Soil water erosion on Mediterranean vineyards. A review based on published data

    Science.gov (United States)

    Prosdocimi, Massimo; Cerdà, Artemi; Tarolli, Paolo

    2015-04-01

    soil and water management techniques to the farmers and implement soil erosion mitigation policies at appropriate spatial scales. Acknowledgements The RECARE project is funded by the European Commission FP7 program, ENV.2013.6.2-4 "Sustainable land care in Europe". References Blavet, D., De Noni, G., Le Bissonnais, Y., Leonard, M., Maillo, L., Laurent, J.Y., Asseline, J., Leprun, J. C., Arshad, M. A., Roose, E.: Effect of land use and management on the early stages of soil water erosion in French Mediterranean vineyards, Soil & Tillage Research, 106, 124-136, 2009. Brenot, J., Quiquerez, A., Petit, C., Garcia, J.-P., Davy, P.: Soil erosion rates in Burgundian vineyards, Bolletino della Società Geologica Italiana, Volume Speciale 6, 169-174, 2006. Casalí, J., Giménez, R., De Santisteban, L., Alvarez-Mozos, J., Mena, J., Del Valle de Lersundi, J.: Determination of long-term erosion rates in vineyards of Navarre (Spain) using botanical benchmarks, Catena, 78, 12-19, doi:10.1016/ j.catena.2009.02.015, 2009. Cerdà, A., Doerr, S. H.: Soil wettability, runoff and erodibility of major dry-Mediterranean land use types on calcareous soils, Hydrological Processes, 21, 2325-2336, doi: 10.1016/j.catena.2008.03.010, 2007. Ferrero, A., Usowicz, B., Lipiec, J.: Effects of tractor traffic on spatial variability of soil strength and water content in grass covered and cultivated sloping vineyard, Soil & Tillage Research, 84, 127-138, 2005. Leh, M., Bajwa, S., Chaubey, I.: Impact of land use change on erosion risk: and integrated remote sensing geographic information system and modeling methodology, Land Degradation & Development, 24, 409- 421, doi 10.1002/ldr.1137, 2013. Leonard, J., Andrieux, P.: Infiltration characteristics of soils in Mediterranean vineyards in southern France, Catena, 32, 209-223, 1998. Martinez-Casasnovas, J. A., Ramos, M. C., Benites, G.: Soil and water assessment tool soil loss simulation at the sub-basin scale in the Alt Penedès-Anoia vineyard region (NE

  19. The relationship between the connecting peptide of recombined single chain insulin and its biological function

    Institute of Scientific and Technical Information of China (English)

    HUANG; Yiding; (

    2001-01-01

    . et al., The role of C-terminus of insulin B chain and the amino group of B29Lys side chain in the growth promoting activities of insulin, Acta Biochim. Biophys. Sin., 1999, 31: 274-278.[24]Yang, J. T., Wu, C. S., Martinez, H. M., Calculation of protein conformation from circular dichroism, Meth. Enzym., 1986, 130: 208-269.[25]Mirmira, R. G., Tager, H. S., Role of the phenylalanine B24 side chain in directing insulin interaction with its receptor, Importance of main chain conformation, J. Biol. Chem., 1989, 264: 6349-6354.[26]Inouye, M., Intramolecular chaperone: the role of the pro-peptide in protein folding, Enzyme, 1991, 45: 314-321.[27]Murray-Rust, J., McLeod, A. N., Blundell, T. L. et al., Structure and evolution of insulins: Implications for receptor binding, Bioassays, 1992, 14: 325-331.[28]Cheng, S. G., Kim, D. Y., Chio, K. D. et al., Human insulin production from a novel miniproinsulin which has high receptor-binding activity, Biochem. J., 1998, 329: 631-635.

  20. Recording, Visualization and Documentation of 3D Spatial Data for Monitoring Topography in Areas of Cultural Heritage

    Science.gov (United States)

    Maravelakis, Emmanouel; Konstantaras, Antonios; Axaridou, Anastasia; Chrysakis, Ioannis; Xinogalos, Michalis

    2014-05-01

    . Journal of Archaeological Science 40, 176-189 (2012) [6] Sinclair, P., Addis, M., Choi, F., Doerr, M., Lewis, P., Martinez, K.: The Use of CRM Core in Multimedia Annotation. In: First International Workshop on Semantic Web Annotations for Multimedia (2006) [7] Zhiming, Z., et al.: Scientific workflow management: between generality and applicability. In: Proc. the 5th International Conference on Quality Software, Melbourne, Australia, pp. 19-20 (2005) [8] Infrastructure for Spatial Information in Europe. INSPIRE Architecture and Standards Position Paper (2002) [9] Doerr, M., Kritsotaki, A.: Documenting events in metadata. In: The e-volution of Information Communication Technology in Cultural Heritage, pp. 56-61 (2006) [10] Maravelakis, E., Konstantaras, A., Kritsotaki, A., Angelakis, D. and Xinogalos, M.: Analysing User Needs for a Unified 3D Metadata Recording and Exploitation of Cultural Heritage Monuments System, Advances in Visual Computing, Lecture Notes in Computer Science Volume 8034, pp 138-147, (2013) [11] Maravelakis, E., Andrianakis, M., Psarakis, K., Bolanakis, N., Tzatzanis, G., Bilalis, N., Antoniadis, A.: Lessons Learned from Cultural Heritage Digitisation Projects in Crete. In: Proceedings of the 14th International Conference on Virtual Systems and Multimedia, pp. 152-156 (2008)