WorldWideScience

Sample records for heavy particles induced

  1. Review of Heavy-ion Induced Desorption Studies for Particle Accelerators

    CERN Document Server

    Mahner, E

    2008-01-01

    During high-intensity heavy-ion operation of several particle accelerators worldwide, large dynamic pressure rises of orders of magnitude were caused by lost beam ions that impacted under grazing angle onto the vacuum chamber walls. This ion-induced desorption, observed, for example, at CERN, GSI, and BNL, can seriously limit the ion intensity, luminosity, and beam lifetime of the accelerator. For the heavyion program at CERN's Large Hadron Collider collisions between beams of fully stripped lead (208Pb82+) ions with a beam energy of 2.76 TeV/u and a nominal luminosity of 10**27 cm**-2 s**-1 are foreseen. The GSI future project FAIR (Facility for Antiproton and Ion Research) aims at a beam intensity of 10**12 uranium (238U28+) ions per second to be extracted from the synchrotron SIS18. Over the past years an experimental effort has been made to study the observed dynamic vacuum degradations, which are important to understand and overcome for present and future particle accelerators. The paper reviews the resu...

  2. Light charged particle emission in heavy-ion reactions – What have ...

    Indian Academy of Sciences (India)

    coincidence with gamma rays, fission products, evaporation residues have yielded interesting results which bring out the influence of nuclear structure, nuclear mean field and dynamics on the emission of these particles. Keywords. Light charged particles; heavy-ion induced reactions; particle spectra and angular distri-.

  3. Charges collection induced in APS by heavy particles: influence of design parameters

    International Nuclear Information System (INIS)

    Belredon, Xavier

    2003-01-01

    We have studied the design parameters influence on heavy ions-induced charge collection physics in APS. The goal is to determine the key parameters for an optimised space environment 'particle detector' APS design. It appears that diffusion is the dominant charge collection mechanism in all the studied technology types, with a smaller magnitude in case of epitaxial technologies. Following proton irradiation, a delayed charge collection and loss of collected charges have been observed. These phenomena are explained by the combination of carriers diffusion and action of the traps generated in the device. Even if they cannot be avoid in space applications, these effects are reduced in case of epitaxial technologies. This work led to the design parameters definition of an optimized APS 'particle detector' and to its fabrication. The results obtained on this APS confirm the previous conclusions and let us define the detection range of such detectors from 0.03 to 50 MeV.cm 2 .mg -1 . (author) [fr

  4. Heavy-ion-induced, gate-rupture in power MOSFETs

    International Nuclear Information System (INIS)

    Fischer, T.A.

    1987-01-01

    A new, heavy-ion-induced, burnout mechanism has been experimentally observed in power metal-oxide-semiconductor field-effect transistors (MOSFETs). This mechanism occurs when a heavy, charged particle passes through the gate oxide region of n- or p-channel devices having sufficient gate-to-source or gate-to-drain bias. The gate-rupture leads to significant permanent degradation of the device. A proposed failure mechanism is discussed and experimentally verified. In addition, the absolute immunity of p-channel devices to heavy-ion-induced, semiconductor burnout is demonstrated and discussed along with new, non-destructive, burnout testing methods

  5. Heavy particle radiotherapy: prospects and pitfalls

    International Nuclear Information System (INIS)

    Faju, M.R.

    1980-01-01

    The use of heavy particles in radiotherapy of tumor volumes is examined. Particles considered are protons, helium ions, heavy ions, negative pions, and fast neutrons. Advantages and disadvantages are discussed

  6. Heavy ion and proton-induced single event multiple upset

    International Nuclear Information System (INIS)

    Reed, R.A.; Carts, M.A.; Marshall, P.W.

    1997-01-01

    Individual ionizing heavy ion events are shown to cause two or more adjacent memory cells to change logic states in a high density CMOS SRAM. A majority of the upsets produced by normally incident heavy ions are due to single-particle events that causes a single cell to upset. However, for grazing angles a majority of the upsets produced by heavy-ion irradiation are due to single-particle events that cause two or more cells to change logic states. Experimental evidence of a single proton-induced spallation reaction that causes two adjacent memory cells to change logic states is presented. Results from a dual volume Monte-Carlo simulation code for proton-induced single-event multiple upsets are within a factor of three of experimental data for protons at normal incidence and 70 degrees

  7. Combination of chemotherapy and heavy-ion particle therapy for pancreas cancer

    International Nuclear Information System (INIS)

    Yamada, Shigeru; Ando, Koichi

    2003-01-01

    The purpose of this study is to investigate the combination of chemotherapy and heavy-ion particle therapy for pancreas cancer. We measured surviving fractions in four culture pancreas cancer cells. The cell killing of heavy-ion irradiation is more effective compared to that of X ray irradiation. Gemcitabine induced radiosensitization for pancreas cancer cells. (author)

  8. Combination of chemotherapy and heavy-ion particle therapy for pancreas cancer

    International Nuclear Information System (INIS)

    Yamada, Shigeru; Ando, Koichi

    2004-01-01

    The purpose of this study is to investigate the combination of chemotherapy and heavy-ion particle therapy for pancreas cancer. We measured surviving fractions in four culture pancreas cancer cells. The cell killing of heavy-ion irradiation is more effective compared to that of X ray irradiation. Gemcitabine induced radiosensitization for pancreas cancer cells. (author)

  9. Heavy Particle Beams in Tumor Radiotherapy

    International Nuclear Information System (INIS)

    Ayad, M.

    1999-01-01

    Using heavy particles beam in the tumor radiotherapy is advantageous to the conventional radiation with photons and electrons. One of the advantages of the heavy charged particle is the energy deposition processes which give a well defined range in tissue, a Bragg peak of ionization in the depth-dose distribution and slow scattering, while the dose to the surrounding healthy tissue in the vicinity is minimized. These processes can show the relation between the heavy particle and the conventional radiation is illustrated with respect to the depth dose and the relative dose. The usage of neutrons (Thermal or epithermal) in therapy necessitates implementation of capture material leading to the production of heavy charged particles (a-particles) as a result of the nuclear interaction in between. Experimentally it is found that 80% of the absorbed dose is mainly due to the presence of capture material

  10. Cell inactivation by heavy charged particles

    Energy Technology Data Exchange (ETDEWEB)

    Blakely, E A [Lawrence Berkeley Lab., CA (United States). Cell and Molecular Biology Div.

    1992-06-01

    The inactivation of cells resulting in lethal or aberrant effects by charged particles is of growing interest. Charged particles at extremely high LET are capable of completely eliminating cell-type and cell-line differences in repair capacity. It is still not clear however whether the repair systems are inactivated, or merely that heavy-ion lesions are less repairable. Studies correlating the particle inactivation dose of radioresistant cells with intact DNA analyzed with pulse field gel electrophoresis and other techniques may be useful, but more experiments are also needed to assess the fidelity of repair. For particle irradiations between 40-100 keV/{mu}m there is however evidence for particle-induced activation of specific genes in mammalian cells, and certain repair processes in bacteria. New data are available on the inactivation of developmental processes in several systems including seeds, and cells of the nematode C. elegans. Future experimental and theoretical modeling research emphasis should focus on exploring particle-induced inactivation of endpoints assessing functionality and not just lethality, and on analyzing molecular damage and genetic effects arising in damage but non-inactivated survivors. The discrete nature of selective types of particle damage as a function of radiation quality indicates the value of accelerated ions as probes of normal and aberrant biological processes. Information obtained from molecular analyses of damage and repair must however be integrated into the context of cellular and tissue functions of the organism. (orig.).

  11. Effect of heavy particles in low-energy light-particle processes

    International Nuclear Information System (INIS)

    Chan, L.H.; Hagiwara, T.; Ovrut, B.

    1979-01-01

    The ''decoupling theorem'' of Appelquist and Carazzone is found not always to be applicable to light-scalar-particle processes in spontaneously broken theories. If the Higgs scalar is considered to be light, then Higgs-scalar processes see the effect of heavy fermions and heavy vector gauge bosons at the one-loop level. If there is more than one scalar multiplet in a spontaneously broken gauge theory, the effect of a heavy Higgs particle in light-scalar-particle processes is significant at the tree level. In the latter case, such an effect can be absorbed completely into an effective phi 4 coupling constant, lambda/sub eff/, of the light particle provided that lambda/sub eff/ is positive definite

  12. Combination of chemotherapy and heavy-ion particle therapy for gastrointestinal cancer

    International Nuclear Information System (INIS)

    Yamada, Shigeru; Kitabayashi, Hiroyuki; Furusawa, Yoshiya; Ando, Koichi

    2005-01-01

    The purpose of this study is to investigate the combination of chemotherapy and heavy-ion particle therapy for pancreas and esophageal cancer. We measured surviving fractions in four culture pancreas and esophageal cancer cells. The cell killing of heavy-ion irradiation is more effective compared to that of X ray irradiation. Gemcitabine induced radiosensitization for pancreas cancer cells and also taxotel for esophageal cancer. (author)

  13. Simulation of thermal-neutron-induced single-event upset using particle and heavy-ion transport code system

    International Nuclear Information System (INIS)

    Arita, Yutaka; Kihara, Yuji; Mitsuhasi, Junichi; Niita, Koji; Takai, Mikio; Ogawa, Izumi; Kishimoto, Tadafumi; Yoshihara, Tsutomu

    2007-01-01

    The simulation of a thermal-neutron-induced single-event upset (SEU) was performed on a 0.4-μm-design-rule 4 Mbit static random access memory (SRAM) using particle and heavy-ion transport code system (PHITS): The SEU rates obtained by the simulation were in very good agreement with the result of experiments. PHITS is a useful tool for simulating SEUs in semiconductor devices. To further improve the accuracy of the simulation, additional methods for tallying the energy deposition are required for PHITS. (author)

  14. Heavy-ion radiography applied to charged particle radiotherapy

    International Nuclear Information System (INIS)

    Chen, G.T.Y.; Fabrikant, J.I.; Holley, W.R.; Tobias, C.A.; Castro, J.R.

    1980-01-01

    The objectives of the heavy-ion radiography research program applied to the clinical cancer research program of charged particle radiotherapy have a twofold purpose: (1) to explore the manner in which heavy-ion radiography and CT reconstruction can provide improved tumor localization, treatment planning, and beam delivery for radiotherapy with accelerated heavy charged particles; and (2) to explore the usefulness of heavy-ion radiography in detecting, localizing, and sizing soft tissue cancers in the human body. The techniques and procedures developed for heavy-ion radiography should prove successful in support of charged particle radiotherapy

  15. Heavy particle irradiation, neurochemistry and behavior: thresholds, dose-response curves and recovery of function

    Science.gov (United States)

    Rabin, B. M.; Joseph, J. A.; Shukitt-Hale, B.

    2004-01-01

    Exposure to heavy particles can affect the functioning of the central nervous system (CNS), particularly the dopaminergic system. In turn, the radiation-induced disruption of dopaminergic function affects a variety of behaviors that are dependent upon the integrity of this system, including motor behavior (upper body strength), amphetamine (dopamine)-mediated taste aversion learning, and operant conditioning (fixed-ratio bar pressing). Although the relationships between heavy particle irradiation and the effects of exposure depend, to some extent, upon the specific behavioral or neurochemical endpoint under consideration, a review of the available research leads to the hypothesis that the endpoints mediated by the CNS have certain characteristics in common. These include: (1) a threshold, below which there is no apparent effect; (2) the lack of a dose-response relationship, or an extremely steep dose-response curve, depending on the particular endpoint; and (3) the absence of recovery of function, such that the heavy particle-induced behavioral and neural changes are present when tested up to one year following exposure. The current report reviews the data relevant to the degree to which these characteristics are common to neurochemical and behavioral endpoints that are mediated by the effects of exposure to heavy particles on CNS activity.

  16. Mechanism of 238U disintegration induced by relativistic particles

    International Nuclear Information System (INIS)

    Andronenko, L.N.; Zhdanov, A.A.; Kravtsov, A.V.; Solyakin, G.E.

    2002-01-01

    In heavy-nucleus disintegration induced by a relativistic projectile particle, the production of collinear massive fragments accompanied by numerous charged particles and neutrons is explained in terms of the mechanism of projectile-momentum compensation due to the emission of a particle whose mass is greater than the projectile mass

  17. TOF for heavy stable particle identification

    International Nuclear Information System (INIS)

    Chang, C.Y.

    1983-01-01

    Searching for heavy stable particle production in a new energy region of hadron-hadron collisions is of fundamental theoretical interest. Observation of such particles produced in high energy collisions would indicate the existence of stable heavy leptons or any massive hadronic system carrying new quantum numbers. Experimentally, evidence of its production has not been found for PP collisions either at FNAL or at the CERN ISR for √S = 23 and 62 GeV respectively. However, many theories beyond the standard model do predict its existence on a mass scale ranging from 50 to a few hundred GeV. If so, it would make a high luminosity TeV collider an extremely ideal hunting ground for searching the production of such a speculated object. To measure the mass of a heavy stable charged particle, one usually uses its time of flight (TOF) and/or dE/dX information. For heavy neutral particle, one hopes it may decay at some later time after its production. Hence a pair of jets or a jet associated with a high P/sub t/ muon originated from some places other than the interacting point (IP) of the colliding beams may be a good signal. In this note, we examine the feasibility of TOF measurement on a heavy stable particle produced in PP collisions at √S = 1 TeV and a luminosity of 10 33 cm -2 sec -1 with a single arm spectrometer pointing to the IP

  18. Heavy-Ion-Induced Electronic Desorption of Gas from Metals

    CERN Document Server

    Molvik, A W; Mahner, E; Kireeff Covo, M; Bellachioma, M C; Bender, M; Bieniosek, F M; Hedlund, E; Krämer, A; Kwan, J; Malyshev, O B; Prost, L; Seidl, P A; Westenskow, G; Westerberg, L

    2007-01-01

    During heavy-ion operation in several particle accelerators worldwide, dynamic pressure rises of orders of magnitude were triggered by lost beam ions that bombarded the vacuum chamber walls. This ion-induced molecular desorption, observed at CERN, GSI, and BNL, can seriously limit the ion beam lifetime and intensity of the accelerator. From dedicated test stand experiments we have discovered that heavy-ion-induced gas desorption scales with the electronic energy loss (dEe/dx) of the ions slowing down in matter; but it varies only little with the ion impact angle, unlike electronic sputtering.

  19. Heavy ion induced DNA strand breaks and their repair in diploid cells of the epithelium of the lens

    International Nuclear Information System (INIS)

    Heilman, J.

    1987-11-01

    This diploma thesis investigates by means of alkaline unwinding and neutral elution the induction of DNA strand breaks and of rejoining processes as an effect of irradiation with very heavy, accelerated ions. It is found that: The effectiveness of very heavy ions (Z > 18) increases per particle with higher ordinal number, and with increasing velocities. The relative biological effectiveness increases with higher particle masses and lower velocities. The effects of very heavy ions are determined both by the LET and by the particle track extension (specific energy) of the various particles. Heavy ions are much more effective than X-rays with regard to inducing double strand breaks, as compared to DNA single strand breaks induced. Rejoining processes induced by heavy ions have been found to be delayed and incomplete, as compared to the X-ray effects. The number of rejoining processes decreases with rising ordinal number. The experiments indicate that the irradiation with lead or uranium ions most probably makes rejoining impossible. (orig./MG) [de

  20. Clinical results in heavy particle radiotherapy

    International Nuclear Information System (INIS)

    Castro, J.R.; Quivey, J.M.; Saunders, W.M.; Woodruff, K.H.; Chen, G.T.Y.; Lyman, J.T.; Pitluck, S.; Tobias, C.A.; Walton, R.E.; Peters, T.C.

    1980-01-01

    The chapter presents an overview of the use of heavy particles in human cancer radiotherapy. The biophysical characteristics and rationale for using heavy charged particle therapy are explored. The clinical experience with carbon, neon, argon and helium are summarized for various types of tumors including carcinomas of the uterine cervix and lung, skin melanomas and metastatic sarcomas. No obvious normal tissue complications have appeared

  1. Damage induced in semiconductors by swift heavy ion irradiation

    International Nuclear Information System (INIS)

    Levalois, M.; Marie, P.

    1999-01-01

    The behaviour of semiconductors under swift heavy ion irradiation is different from that of metals or insulators: no spectacular effect induced by the inelastic energy loss has been reported in these materials. We present here a review of irradiation effects in the usual semiconductors (silicon, germanium and gallium arsenide). The damage is investigated by means of electrical measurements. The usual mechanisms of point defect creation can account for the experimental results. Besides, some results obtained on the wide gap semiconductor silicon carbide are reported. Concerning the irradiation effects induced by heavy ions in particle detectors, based on silicon substrate, we show that the deterioration of the detector performances can be explained from the knowledge of the substrate properties which are strongly perturbed after high doses of irradiation. Finally, some future ways of investigation are proposed. The silicon substrate is a good example to compare the irradiation effects with different particles such as electrons, neutrons and heavy ions. It is then necessary to use parameters which account for the local energy deposition, in order to describe the damage in the material

  2. Study of the Particle Production in $^{12}$C Induced Heavy Ion Reactions at 86 MeV/N

    CERN Multimedia

    2002-01-01

    The aim of this experiment is to study various characteristics of light and heavy particle production in |1|2C induced reactions if possible over the whole unexplored energy region 50-86~MeV/N. In particular we want to investigate how the correlations in the multiparticle events can help us to distinguish bet existing models. \\\\ \\\\ Two-proton large-angle correlations and correlations between two heavier (Z~=~1 or 2) particles are studied with scintillator +~NaI and range telescopes, complemented with a 24 telescope scintillator wall for projectile fragments. Thereby we receive information about the reaction plane and the impact parameter in coincidence with the two-particle correlation spectra. Small @Dp correlations can also be studied. The inclusive @p|+ and @p|- production has been followed far below the nucleon-nucleon threshold. Pions are thereby identified from @DE-E correlations and the @p|+ decay in plastic range telescopes. These results are now followed up by @p-projectile fragment and @p-p correlat...

  3. A large area position-sensitive ionization chamber for heavy-ion-induced reaction studies

    CERN Document Server

    Pant, L M; Dinesh, B V; Thomas, R G; Saxena, A; Sawant, Y S; Choudhury, R K

    2002-01-01

    A large area position-sensitive ionization chamber with a wide dynamic range has been developed to measure the mass, charge and energy of the heavy ions and the fission fragments produced in heavy-ion-induced reactions. The split anode geometry of the detector makes it suitable for both particle identification and energy measurements for heavy ions and fission fragments. The detector has been tested with alpha particles from sup 2 sup 4 sup 1 Am- sup 2 sup 3 sup 9 Pu source, fission fragments from sup 2 sup 5 sup 2 Cf and the heavy-ion beams from the 14UD Mumbai Pelletron accelerator facility. Using this detector, measurements on mass and total kinetic energy distributions in heavy-ion-induced fusion-fission reactions have been carried out for a wide range of excitation energies. Results on deep inelastic collisions and mass-energy correlations on different systems using this detector setup are discussed.

  4. Suppression and Two-Particle Correlations of Heavy Mesons in Heavy-Ion Collisions

    Energy Technology Data Exchange (ETDEWEB)

    Cao, Shanshan [Nuclear Science Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720 (United States); Qin, Guang-You [Institute of Particle Physics and Key Laboratory of Quark and Lepton Physics (MOE), Central China Normal University, Wuhan, 430079 (China); Bass, Steffen A. [Department of Physics, Duke University, Durham, NC 27708 (United States)

    2016-12-15

    We study the medium modification of heavy quarks produced in heavy-ion collisions. The evolution of heavy quarks inside the QGP is described using a modified Langevin framework that simultaneously incorporates their collisional and radiative energy loss. Within this framework, we provide good descriptions of the heavy meson suppression and predictions for the two-particle correlation functions of heavy meson pairs.

  5. Exposure to heavy charged particles affects thermoregulation in rats

    International Nuclear Information System (INIS)

    Kandasamy, S.B.; Hunt, W.A.; Dalton, T.K.; Joseph, J.A.; Harris, A.H.; Rabin, B.M.

    1994-01-01

    Rats exposed to 0.1-5 Gy of heavy particles ( 56 Fe, 40 Ar, 20 Ne or 4 He) showed dose-dependent changes in body temperature. Lower doses of all particles produced hyperthermia, and higher doses of 20 Ne and 56 Fe produced hypothermia. Of the four HZE particles, 56 Fe particles were the most potent and 4 He particles were the least potent in producing changes in thermoregulation. The 20 Ne and 40 Ar particles produced an intermediate level of change in body temperature. Significantly greater hyperthermia was produced by exposure to 1 Gy of 20 Ne, 40 Ar and 56 Fe particles than by exposure to 1 Gy of 60 Co γ rays. Pretreating rats with the cyclo-oxygenase inhibitor indomethacin attenuated the hyperthermia produced by exposure to 1 Gy of 56 Fe particles, indicating that prostaglandins mediate 56 Fe-particle-induced hyperthermia. The hypothermia produced by exposure to 5 Gy of 56 Fe particles is mediated by histamine and can be attenuated by treatment with the antihistamines mepyramine and cimetidine. 15 refs., 4 figs

  6. Search for heavy particles

    International Nuclear Information System (INIS)

    Barnett, R.M.

    1977-03-01

    Direct and indirect evidence for the existence of a new heavy quark b and of new heavy neutral leptons N/sub e/ and N/sub μ/ can be sought in neutrino and e + e - scattering. These particles are expected to have right-handed currents. Discussion is given on the characteristics, production and decay of hadrons such as bb, ub and db, and of the massive neutral leptons. Muon number violation with and without N/sub e/ and N/sub μ/ is considered

  7. Particle Interferometry for Relativistic Heavy-Ion Collisions

    CERN Document Server

    Wiedemann, Urs Achim; Wiedemann, Urs Achim; Heinz, Ulrich

    1999-01-01

    In this report we give a detailed account on Hanbury Brown/Twiss (HBT) particle interferometric methods for relativistic heavy-ion collisions. These exploit identical two-particle correlations to gain access to the space-time geometry and dynamics of the final freeze-out stage. The connection between the measured correlations in momentum space and the phase-space structure of the particle emitter is established, both with and without final state interactions. Suitable Gaussian parametrizations for the two-particle correlation function are derived and the physical interpretation of their parameters is explained. After reviewing various model studies, we show how a combined analysis of single- and two-particle spectra allows to reconstruct the final state of relativistic heavy-ion collisions.

  8. Particle production in heavy ion collisions

    International Nuclear Information System (INIS)

    Braun-Munzinger, P.; Redlich, K.; Wroclaw Univ.; Stachel, J.

    2003-04-01

    The status of thermal model descriptions of particle production in heavy ion collisions is presented. We discuss the formulation of statistical models with different implementation of the conservation laws and indicate their applicability in heavy ion and elementary particle collisions. We analyze experimental data on hadronic abundances obtained in ultra-relativistic heavy ion collisions, in a very broad energy range starting from RHIC/BNL (√(s) = 200 A GeV), SPS/CERN (√(s) ≅ 20 A GeV) up to AGS/BNL (√(s) ≅ 5 A GeV) and SIS/GSI (√(s) ≅ 2 A GeV) to test equilibration of the fireball created in the collision. We argue that the statistical approach provides a very satisfactory description of experimental data covering this wide energy range. Any deviations of the model predictions from the data are indicated. We discuss the unified description of particle chemical freeze-out and the excitation functions of different particle species. At SPS and RHIC energy the relation of freeze-out parameters with the QCD phase boundary is analyzed. Furthermore, the application of the extended statistical model to quantitative understanding of open and hidden charm hadron yields is considered. (orig.)

  9. Various light particles emissions accompaning light heavy ion collisions

    International Nuclear Information System (INIS)

    Billerey, R.

    1981-01-01

    In this work we have investigated light particles emission accompanying heavy-ion induced reactions. The experiments were performed at the isochronous cyclotron of the I.S.N. de Grenoble and we got in and out of plane correlations between solid state and gazeous detectors. In 14 N (100 MeV) + 27 Al we have chosen, light particles emitted in coincidence with deep inelastic fragments or evaporation residues have been measured. Likewise we observed the correlations between fragments and fragments. The particularities we found between protons and alpha emissions are to be assigned to differences in separation energies, but their relative energies and angular momenta have also a significant part [fr

  10. Physical aspects of heavy charged particle beams for radiotherapy

    International Nuclear Information System (INIS)

    Kawashima, Katsuhiro

    1989-01-01

    Physical properties of heavy ion beams are discussed to improve the physical dose distributions in view of radiotherapy. Preservation of the structural and functional integrity of adjacent normal tissue is required to achieve great probability of tumor control. This will be accomplished with the reduction of irradiated volume of normal tissues and with greater relative biological effectiveness (RBE) on tumor cells than that on surrounding normal cells. This suggests the use of heavy ion beams as new source of radiation that increases the therapeutic ratio. The basis of the improvement in the physical dose distribution by use of heavy charged particles is due to the finite range of the beams and to the less multiple coulomb scattering of the particles having a heavier atomic mass than proton. The depth dose distributions and dose profiles of heavy particle beams are discussed in this article. The lateral sharpness of heavy charged particles is comparable to the penumbra of high energy photon and electron beams and is not of clinical concern due to less coulomb scattering of heavy ions to lateral direction in traversing a medium. The dose gradient at the end of range of primary beam is dependent upon the energy spread and range straggling of the particles. The magnitude of range straggling is nearly proportional to the range and inversely proportional to the inverse square root of the particle mass. Heavy ion beams also undergo nuclear interactions, in which the primary beam may produce lower atomic number particles. Therefore, the dose beyond the Bragg peak is due to those fragments. Fragmentation increases as a function of the atomic mass to the 2/3 power and with the energy of the particles. Thus, the production of fragments diminishes the depth dose advantages of heavy ions. The choice of ion for radiotherapy may depend on evaluation of important parameter for tumor control. (J.P.N.)

  11. Solar Particle Induced Upsets in the TDRS-1 Attitude Control System RAM During the October 1989 Solar Particle Events

    Science.gov (United States)

    Croley, D. R.; Garrett, H. B.; Murphy, G. B.; Garrard,T. L.

    1995-01-01

    The three large solar particle events, beginning on October 19, 1989 and lasting approximately six days, were characterized by high fluences of solar protons and heavy ions at 1 AU. During these events, an abnormally large number of upsets (243) were observed in the random access memory of the attitude control system (ACS) control processing electronics (CPE) on-board the geosynchronous TDRS-1 (Telemetry and Data Relay Satellite). The RAM unit affected was composed of eight Fairchild 93L422 memory chips. The Galileo spacecraft, launched on October 18, 1989 (one day prior to the solar particle events) observed the fluxes of heavy ions experienced by TDRS-1. Two solid-state detector telescopes on-board Galileo, designed to measure heavy ion species and energy, were turned on during time periods within each of the three separate events. The heavy ion data have been modeled and the time history of the events reconstructed to estimate heavy ion fluences. These fluences were converted to effective LET spectra after transport through the estimated shielding distribution around the TDRS-1 ACS system. The number of single event upsets (SEU) expected was calculated by integrating the measured cross section for the Fairchild 93L422 memory chip with average effective LET spectrum. The expected number of heavy ion induced SEU's calculated was 176. GOES-7 proton data, observed during the solar particle events, were used to estimate the number of proton-induced SEU's by integrating the proton fluence spectrum incident on the memory chips, with the two-parameter Bendel cross section for proton SEU'S. The proton fluence spectrum at the device level was gotten by transporting the protons through the estimated shielding distribution. The number of calculated proton-induced SEU's was 72, yielding a total of 248 predicted SEU'S, very dose to the 243 observed SEU'S. These calculations uniquely demonstrate the roles that solar heavy ions and protons played in the production of SEU

  12. Taking account of the recoil effect under a light particle scattering on two heavy particles

    International Nuclear Information System (INIS)

    Peresypkin, V.V.

    1978-01-01

    Proceeding from the Faddeev equations the derivation of the Bruekner formula describing a light particle scattering by a system of two fixed force centers is presented. Using the zero-range two-particle potential and assuming the ratio of the incident particle mass to the heavy particle mass to be a small perturbation parameter the correction to the Bruekner formula is obtained taking into account the heavy particle recoil

  13. Photon structure functions with heavy particle mass effects

    Energy Technology Data Exchange (ETDEWEB)

    Uematsu, Tsuneo, E-mail: uematsu@scphys.kyoto-u.jp [Graduate School of Science, Kyoto University, Kitashirakawa, Sakyo-ku, Kyoto, 606-8502 (Japan); Maskawa Institute for Science and Culture, Kyoto Sangyo University, Kamigamo, Kita-ku, Kyoto 603-8555 (Japan)

    2013-01-15

    In the framework of the perturbative QCD we investigate heavy particle mass effects on the unpolarized and polarized photon structure functions, F{sub 2}{sup γ} and g{sub 1}{sup γ}, respectively. We present our basic formalism to treat heavy particle mass effects to NLO in perturbative QCD. We also study heavy quark effects on the QCD sum rule for the first moment of g{sub 1}{sup γ}, which is related to axial anomaly. The photon structure function in supersymmetric QCD is also briefly discussed.

  14. Nuclear dynamics in heavy ion induced fusion-fission reactions

    International Nuclear Information System (INIS)

    Kapoor, S.S.

    1992-01-01

    Heavy ion induced fission and fission-like reactions evolve through a complex nuclear dynamics encountered in the medium energy nucleus-nucleus collisions. In the recent years, measurements of the fragment-neutron and fragment-charged particle angular correlations in heavy ion induced fusion-fission reactions, have provided new information on the dynamical times of nuclear deformations of the initial dinuclear complex to the fission saddle point and the scission point. From the studies of fragment angular distributions in heavy ion induced fission it has been possible to infer the relaxation times of the dinuclear complex in the K-degree of freedom and our recent measurements on the entrance channel dependence of fragment anisotropies have provided an experimental signature of the presence of fissions before K-equilibration. This paper reviews recent experimental and theoretical status of the above studies with particular regard to the questions relating to dynamical times, nuclear dissipation and the effect of nuclear dissipation on the K-distributions at the fission saddle in completely equilibrated compound nucleus. (author). 19 refs., 9 figs

  15. Measurement of heavy particle and isotope

    International Nuclear Information System (INIS)

    Matsuoka, Masaru; Kohno, Takeshi; Imai, Takashi; Munakata, Kazuoki

    1987-01-01

    The report describes some achievements made so far in developing heavy particle and isotope measuring equipment that is planned to be mounted on the No.6 technical test satelite of the National Space Development Agency, ETS VI. Some ideas are proposed for such heavy particle and isotope measuring equipment that uses Astromag. The structure of SSD is shown which is planned to be incorporated in the sensor for the equipment. The planned charged particle detector consists of position sensitive detectors, PIN diodes and Si(Li) plates. Tests are made for the basic characteristics of such a detector. The characteristics of a PSD are also investigated. The PSD has a resolution of about 1 mm for 14 MeV He. Tests of a 0.3 mm PIN diode and 1.2 mm Si(Li) is carried out with 234 MeV-nucl Fe beams to determine their pulse height distribution. The PIN diode and Si(Li) are found to have a resolution of 6.79 and 17.6 MeV for energy loss of 158 and 710 MeV, respectively. If developed, a stripe-type Si PIN diode will serve for analysis of isotopes. A conceptual diagram of such a stripe device is proposed. The mechanism of measurement by a heavy particle and isotope detecting system incorporating Astromag is also illustrated. (Nogami, K.)

  16. Mean motion and trajectories of heavy particles falling through a boundary layer

    Energy Technology Data Exchange (ETDEWEB)

    Stout, J.E.; Arya, S.P. [North Carolina State Univ., Raleigh, NC (United States)

    1994-12-31

    As particles fall through a turbulent boundary layer they experience a rather complex and unique time series of aerodynamic forces and, thus, each individual particle follows a rather complex and unique trajectory to the surface. For sufficiently large and heavy particles, the turbulence induced particle motion can be thought of as a small perturbation superimposed on the mean trajectory. By ignoring the turbulent contribution to particle motion it is possible to calculate the trajectory of a particle due to the mean flow alone. The mean trajectory provides an estimate of the ensemble-averaged path of a set of particles released from a given point in the atmosphere. The effect of turbulence on individual particle trajectories, the distribution of particle displacements from the mean trajectory, and their deposition patterns on the surface will be investigated in a separate study, using a random walk model.

  17. Recent advances in heavy-ion-induced fission

    International Nuclear Information System (INIS)

    Plasil, F.

    1984-01-01

    Three topics are discussed. The first deals with results that have been published recently on angular-momentum-dependent fission barriers. They are discussed because of the significance that we attach to them. We feel that, after a decade of study and controversy, we have arrived at a quantitative understanding of the competition between heavy-ion-induced fission and particle emission from compound nuclei at relatively low bombarding energies. The second topic concerns the extension of our heavy-ion-induced fission studies to higher energies. It is clear that in this regime the effects, both of fission following incomplete fusion and of extra-push requirements, need to be considered. Finally, discussed are our recent conclusions concerning the fissionlike decay of products from reactions between two 58 Ni nuclei at an incident energy, E/A, of 15.3 MeV, as well as the impact of our findings on the conclusions drawn from previous, similar measurements. 39 references

  18. Solar particle induced upsets in the TDRS-1 attitude control system RAM during the October 1989 solar particle events

    International Nuclear Information System (INIS)

    Croley, D.R.; Garrett, H.B.; Murphy, G.B.; Garrard, T.L.

    1995-01-01

    The three large solar particle events, beginning on October 19, 1989 and lasting approximately six days, were characterized by high fluences of solar protons and heavy ions at 1 AU. During these events, an abnormally large number of upsets (243) were observed in the random access memory of the attitude control system (ACS) control processing electronics (CPE) on-board the geosynchronous TDRS-1 (Telemetry and Data Relay Satellite). The RAM unit affected was composed of eight Fairchild 93L422 memory chips. The Galileo spacecraft, launched on October 18, 1989 (one day prior to the solar particle events) observed the fluxes of heavy ions experienced by TDRS-1. Two solid-state detector telescopes on-board Galileo, designed to measure heavy ion species and energy, were turned on during time periods within each of the three separate events. The heavy ion data have been modeled and the time history of the events reconstructed to estimate heavy ion fluences. These fluences were converted to effective LET spectra after transport through the estimated shielding distribution around the TDRS-1 ACS system. The number of single event upsets (SEU) expected was calculated by integrating the measured cross section for the Fairchild 93L422 memory chip with average effective LET spectrum. The expected number of heavy ion induced SEU's calculated was 176. GOES-7 proton data, observed during the solar particle events, were used to estimate the number of proton-induced SEU's by integrating the proton fluence spectrum incident on the memory chips, with the two-parameter Bendel cross section for proton SEU's. The proton fluence spectrum at the device level was gotten by transporting the protons through the estimated shielding distribution. The number of calculated proton-induced SEU's was 72, yielding a total of 248 predicted SEU's, very close to the 243 observed SEU's

  19. PHITS-a particle and heavy ion transport code system

    International Nuclear Information System (INIS)

    Niita, Koji; Sato, Tatsuhiko; Iwase, Hiroshi; Nose, Hiroyuki; Nakashima, Hiroshi; Sihver, Lembit

    2006-01-01

    The paper presents a summary of the recent development of the multi-purpose Monte Carlo Particle and Heavy Ion Transport code System, PHITS. In particular, we discuss in detail the development of two new models, JAM and JQMD, for high energy particle interactions, incorporated in PHITS, and show comparisons between model calculations and experiments for the validations of these models. The paper presents three applications of the code including spallation neutron source, heavy ion therapy and space radiation. The results and examples shown indicate PHITS has great ability of carrying out the radiation transport analysis of almost all particles including heavy ions within a wide energy range

  20. On the spatial distribution of small heavy particles in homogeneous shear turbulence

    Science.gov (United States)

    Nicolai, C.; Jacob, B.; Piva, R.

    2013-08-01

    We report on a novel experiment aimed at investigating the effects induced by a large-scale velocity gradient on the turbulent transport of small heavy particles. To this purpose, a homogeneous shear flow at Reλ = 540 and shear parameter S* = 4.5 is set-up and laden with glass spheres whose size d is comparable with the Kolmogorov lengthscale η of the flow (d/η ≈ 1). The particle Stokes number is approximately 0.3. The analysis of the instantaneous particle fields by means of Voronoï diagrams confirms the occurrence of intense turbulent clustering at small scales, as observed in homogeneous isotropic flows. It also indicates that the anisotropy of the velocity fluctuations induces a preferential orientation of the particle clusters. In order to characterize the fine-scale features of the dispersed phase, spatial correlations of the particle field are employed in conjunction with statistical tools recently developed for anisotropic turbulence. The scale-by-scale analysis of the particle field clarifies that isotropy of the particle distribution is tendentially recovered at small separations, even though the signatures of the mean shear persist down to smaller scales as compared to the fluid velocity field.

  1. L X-ray emission induced by heavy ions

    Energy Technology Data Exchange (ETDEWEB)

    Pajek, M. [Institute of Physics, Jan Kochanowski University, 25-406 Kielce (Poland); Banaś, D., E-mail: d.banas@ujk.edu.pl [Institute of Physics, Jan Kochanowski University, 25-406 Kielce (Poland); Braziewicz, J.; Majewska, U.; Semaniak, J. [Institute of Physics, Jan Kochanowski University, 25-406 Kielce (Poland); Fijał-Kirejczyk, I. [The Institute of Atomic Energy, 05-400 Otwock-Świerk (Poland); Jaskóła, M.; Czarnacki, W.; Korman, A. [The National Centre for Nuclear Research, 05-400 Otwock-Świerk (Poland); Kretschmer, W. [Physikalisches Institut, Universität Erlangen-Nürnberg, D-91058 Erlangen (Germany); Mukoyama, T. [Institute for Nuclear Research, Hungarian Academy of Sciences (ATOMKI), H-4026 Debrecen (Hungary); Trautmann, D. [Institut für Physik, Universität Basel, Basel (Switzerland)

    2015-11-15

    Particle-induced X-ray emission (PIXE) technique is usually applied using typically 1 MeV to 3 MeV protons or helium ions, for which the ion-atom interaction is dominated by the single ionization process. For heavier ions the multiple ionization plays an increasingly important role and this process can influence substantially both the X-ray spectra and atomic decay rates. Additionally, the subshell coupling effects are important for the L- and M-shells ionized by heavy ions. Here we discuss the main features of the X-ray emission induced by heavy ions which are important for PIXE applications, namely, the effects of X-ray line shifts and broadening, vacancy rearrangement and change of the fluorescence and Coster–Kronig yields in multiple ionized atoms. These effects are illustrated here by the results of the measurements of L X-ray emission from heavy atoms bombarded by 6 MeV to 36 MeV Si ions, which were reported earlier. The strong L-subshell coupling effects are observed, in particular L{sub 2}-subshell, which can be accounted for within the coupling subshell model (CSM) developed within the semiclassical approximation. Finally, the prospects to use heavy ions in PIXE analysis are discussed.

  2. Quasi-particle interference of heavy fermions in resonant x-ray scattering.

    Science.gov (United States)

    Gyenis, András; da Silva Neto, Eduardo H; Sutarto, Ronny; Schierle, Enrico; He, Feizhou; Weschke, Eugen; Kavai, Mariam; Baumbach, Ryan E; Thompson, Joe D; Bauer, Eric D; Fisk, Zachary; Damascelli, Andrea; Yazdani, Ali; Aynajian, Pegor

    2016-10-01

    Resonant x-ray scattering (RXS) has recently become an increasingly important tool for the study of ordering phenomena in correlated electron systems. Yet, the interpretation of RXS experiments remains theoretically challenging because of the complexity of the RXS cross section. Central to this debate is the recent proposal that impurity-induced Friedel oscillations, akin to quasi-particle interference signals observed with a scanning tunneling microscope (STM), can lead to scattering peaks in RXS experiments. The possibility that quasi-particle properties can be probed in RXS measurements opens up a new avenue to study the bulk band structure of materials with the orbital and element selectivity provided by RXS. We test these ideas by combining RXS and STM measurements of the heavy fermion compound Ce M In 5 ( M = Co, Rh). Temperature- and doping-dependent RXS measurements at the Ce- M 4 edge show a broad scattering enhancement that correlates with the appearance of heavy f -electron bands in these compounds. The scattering enhancement is consistent with the measured quasi-particle interference signal in the STM measurements, indicating that the quasi-particle interference can be probed through the momentum distribution of RXS signals. Overall, our experiments demonstrate new opportunities for studies of correlated electronic systems using the RXS technique.

  3. Systematics of quasi-elastic processes induced by heavy ions

    International Nuclear Information System (INIS)

    Baltz, A.J.

    1976-01-01

    An attempt is made to delineate the areas in the systematics of quasi-elastic processes induced by heavy ions that are well described theoretically from the specific features that seem not to be understood. One- and two-particle transfer reactions are considered. A general systematic seen in transfer angular distribution data and theory, some successes and failures of the DWBA and coupled-channels theories in describing heavy-ion-reaction data, and the specific example 232 Th( 40 Ar,K) and implications for deep inelastic reactions with even heavier projectiles such as Kr and Xe are considered

  4. Light-particle emission and heavy residues from nucleus-nucleus collisions

    International Nuclear Information System (INIS)

    Caplar, R.; Hoelbling, S.; Gentner, R.; Lassen, L.; Oberstedt, A.

    1991-01-01

    We have investigated the interrelation between light-particle multiplicities and mass resp. charge distributions of heavy residues from complete and incomplete fusion of heavy ions. We have shown that a simple statistical model provides the possibility of quantitatively correlating heavy-residue distributions and corresponding light-particle multiplicities both at the Coulomb barrier and at higher energies where preequilibrium emission occurs. (author). 8 refs, 4 figs, 1 tab

  5. Heavy particle production at the SSC

    International Nuclear Information System (INIS)

    Brodsky, S.J.; Haber, H.E.; Gunion, J.F.

    1984-03-01

    Predictions for the production of heavy quarks, supersymmetric particles, and other colored systems at high energy due to intrinsic twist-six components in the proton wavefunction are given. We also suggest the possibility of using asymmetric collision energies (e.g., via intersecting rings at the SSC) in order to facilitate the study of forward and diffractive particle production processes. 9 references

  6. Perturbative effect of heavy particles in an effective-Lagrangian approach

    International Nuclear Information System (INIS)

    Hagiwara, T.; Nakazawa, N.

    1981-01-01

    An effective-Lagrangian approach is summarized to estimate the perturbative effect of heavy-mass particles in the leading-logarithmic approximation: the logarithmic corrections to mass-suppressed amplitudes are given in a concise form. We apply the formalism to a simplified model with two scalar fields where one is heavy and the other is light. We derive an effective Lagrangian by calculating heavy-particle one-loop diagrams. Solving renormalization-group equations derived from the effective Lagrangian by light-particle one-loop corrections, we obtain logarithmic corrections to the mass-suppressed amplitudes. The results are confirmed by explicit two-loop calculation in the full theory, up to order O((1/M 2 )1nM 2 ), where M is a heavy scalar mass. It is found that the boundary condition for solving the renormalization-group equations must be specified by the renormalization at the heavy-particle mass. It must also be emphasized that in an effective-Lagrangian approach minimal subtraction is not a proper method of renormalization. The necessity to adopt the conventional momentum-shell subtraction is stressed. Several applications of this formalism are also mentioned

  7. Development of particle and heavy ion transport code system

    International Nuclear Information System (INIS)

    Niita, Koji

    2004-01-01

    Particle and heavy ion transport code system (PHITS) is 3 dimension general purpose Monte Carlo simulation codes for description of transport and reaction of particle and heavy ion in materials. It is developed on the basis of NMTC/JAM for design and safety of J-PARC. What is PHITS, it's physical process, physical models and development process of PHITC code are described. For examples of application, evaluation of neutron optics, cancer treatment by heavy particle ray and cosmic radiation are stated. JAM and JQMD model are used as the physical model. Neutron motion in six polar magnetic field and gravitational field, PHITC simulation of trace of C 12 beam and secondary neutron track of small model of cancer treatment device in HIMAC and neutron flux in Space Shuttle are explained. (S.Y.)

  8. Potential for heavy particle radiation therapy

    International Nuclear Information System (INIS)

    Raju, M.R.; Phillips, T.L.

    1977-03-01

    Radiation therapy remains one of the major forms of cancer treatment. When x rays are used in radiotherapy, there are large variations in radiation sensitivity among tumors because of the possible differences in the presence of hypoxic but viable tumor cells, differences in reoxygenation during treatment, differences in distribution of the tumor cells in their cell cycle, and differences in repair of sublethal damage. When high-LET particles are used, depending upon the LET distribution, these differences are reduced considerably. Because of these differences between x rays and high-LET particle effects, the high-LET particles may be more effective on tumor cells for a given effect on normal cells. Heavy particles have potential application in improving radiotherapy because of improved dose localization and possible advantages of high-LET particles due to their radiobiological characteristics. Protons, because of their defined range, Bragg peak, and small effects of scattering, have good dose localization characteristics. The use of protons in radiotherapy minimizes the morbidity of radiotherapy treatment and is very effective in treating deep tumors located near vital structures. Fast neutrons have no physical advantages over 60 Co gamma rays but, because of their high-LET component, could be very effective in treating tumors that are resistant to conventional radiations. Negative pions and heavy ions combine some of the advantages of protons and fast neutrons

  9. Amorphization of complex ceramics by heavy-particle irradiations

    International Nuclear Information System (INIS)

    Ewing, R.C.; Wang, L.M.

    1994-11-01

    Complex ceramics, for the purpose of this paper, include materials that are generally strongly bonded (mixed ionic and covalent), refractory and frequently good insulators. They are distinguished from simple, compact ceramics (e.g., MgO and UO 2 ) by structural features which include: (1) open network structures, best characterized by a consideration of the shape, size and connectivity of coordination polyhedra; (2) complex compositions which characteristically lead to multiple cation sites and lower symmetry; (3) directional bonding; (4) bond-type variations within the structure. The heavy particle irradiations include ion-beam irradiations and recoil-nucleus damage resulting from a-decay events from constituent actinides. The latter effects are responsible for the radiation-induced transformation to the metamict state in minerals. The responses of these materials to irradiation are complex, as energy may be dissipated ballistically by transfer of kinetic energy from an incident projectile or radiolytically by conversion of radiation-induced electronic excitations into atomic motion. This results in isolated Frenkel defect pairs, defect aggregates, isolated collision cascades or bulk amorphization. Thus, the amorphization process is heterogeneous. Only recently have there been systematic studies of heavy particle irradiations of complex ceramics on a wide variety of structure-types and compositions as a function of dose and temperature. In this paper, we review the conditions for amorphization for the tetragonal orthosilicate, zircon [ZrSiO 4 ]; the hexagonal orthosilicate/phosphate apatite structure-type [X 10 (ZO 4 ) 6 (F,Cl,O) 2 ]; the isometric pyrochlores [A 1-2 B 2 O 6 (O,OH,F) 0-1p H 2 O] and its monoclinic derivative zirconotite [CaZrTi 2 O 7 ]; the olivine (derivative - hcp) structure types, α- VI A 2 IV BO 4 , and spinel (ccp), γ- VI A 2 IV BO 4

  10. Effect of seeds of heavy charged particles of galactic cosmic radiation

    International Nuclear Information System (INIS)

    Maksimova, Y.N.

    1985-01-01

    The experiments were carried out on Lactuca sativa seeds exposed for 20, 66, 123 and 308 days in a biostack also containing physical detectors of heavy charged particles. The yield of aberrant cells and its dependence on the exposure time and the site where particles hit the object were measured. The cytogenetic examination demonstrated a significant difference between the seeds that were or were not hit by heavy charged particles. A significant contribution of galactic cosmic radiation to the radiobiological effect is indicated. The yield of aberrant cells as a function of the localization of heavy charged particles in the seed is established. The most sensitive target is the root meristem

  11. Cataract production in mice by heavy charged particles

    International Nuclear Information System (INIS)

    Ainsworth, E.H.; Jose, J.; Yang, V.V.; Barker, M.E.

    1981-03-01

    The cataractogenic effects of heavy charged particles have been evaluated in mice in relation to dose and ionization density (LET/sub infinity/). The study was undertaken due to the high potential for eye exposures to HZE particles among SPS personnel working in outer space. This has made it imperative that the relative biological effectiveness (RBE) in relation to LET/sub infinity/ for various particles be defined so that appropriate quality factors (Q) could be assigned for estimation of risk. Although mice and men differ in susceptibility to radiation-induced cataracts, the results from this project should assist in defining appropriate quality factors in relation to LET/sub infinity/, particle mass, charge, or velocity. Evaluation of results indicated that : (1) low single doses (5 to 20 rad) of iron ( 56 Fe) or argon ( 40 Ar) particles are cataractogenic at 11 to 18 months after irradiation; (2) onset and density of the opacification are dose related; (3) cataract density (grade) at 9, 11, 13, and 16 months after irradiation shows partial LET/sub infinity/-dependence; and (4) the severity of cataracts is reduced significantly when 417 rad of 60 Co gamma radiation is given in 24 weekly 17 rad fractions compared to giving this radiation as a single dose, but cataract severity is not reduced by fractionation of 12 C doses over 24 weeks

  12. Constituent quarks and charge particle production in heavy-ion collisions

    International Nuclear Information System (INIS)

    Mishra, Aditya Nath; Mazumder, Rakesh; Sahoo, Raghunath; Nandi, Basanta Kumar

    2012-01-01

    Relativistic heavy-ion collisions aims at producing a state of matter which is governed by partonic degree of freedom. The pseudorapidity density of particle multiplicity and transverse energy are the key observables which provide the properties of matter produced in heavy-ion collisions. Study of their dependence on centrality and collision energy is of paramount importance to understand the particle production mechanism. This may provide insight into the partonic phase that might be created in nuclear collisions. Here, in a constituent quarks framework, charged particle and transverse energy production in heavy-ion collisions are studied both as a function of centrality and collision energy, and hence the study gives a prediction for Pb + Pb collisions

  13. Particle and heavy ion transport code system; PHITS

    International Nuclear Information System (INIS)

    Niita, Koji

    2004-01-01

    Intermediate and high energy nuclear data are strongly required in design study of many facilities such as accelerator-driven systems, intense pulse spallation neutron sources, and also in medical and space technology. There is, however, few evaluated nuclear data of intermediate and high energy nuclear reactions. Therefore, we have to use some models or systematics for the cross sections, which are essential ingredients of high energy particle and heavy ion transport code to estimate neutron yield, heat deposition and many other quantities of the transport phenomena in materials. We have developed general purpose particle and heavy ion transport Monte Carlo code system, PHITS (Particle and Heavy Ion Transport code System), based on the NMTC/JAM code by the collaboration of Tohoku University, JAERI and RIST. The PHITS has three important ingredients which enable us to calculate (1) high energy nuclear reactions up to 200 GeV, (2) heavy ion collision and its transport in material, (3) low energy neutron transport based on the evaluated nuclear data. In the PHITS, the cross sections of high energy nuclear reactions are obtained by JAM model. JAM (Jet AA Microscopic Transport Model) is a hadronic cascade model, which explicitly treats all established hadronic states including resonances and all hadron-hadron cross sections parametrized based on the resonance model and string model by fitting the available experimental data. The PHITS can describe the transport of heavy ions and their collisions by making use of JQMD and SPAR code. The JQMD (JAERI Quantum Molecular Dynamics) is a simulation code for nucleus nucleus collisions based on the molecular dynamics. The SPAR code is widely used to calculate the stopping powers and ranges for charged particles and heavy ions. The PHITS has included some part of MCNP4C code, by which the transport of low energy neutron, photon and electron based on the evaluated nuclear data can be described. Furthermore, the high energy nuclear

  14. Investigation of the production of slow particles in 60 A GeV 16O induced nuclear emulsion reaction

    International Nuclear Information System (INIS)

    Zhang Donghai

    2001-01-01

    The multiplicity distributions and correlations of grey track producing particles (N g ), black track producing particles (N b ) and heavy track producing particles (N h ) have been studied in 60 A GeV 16 O induced nuclear emulsion reaction. The multiplicity distributions of grey particles, black particles and heavy track producing particles can be reproduced by FRITIOF (version 1.7) taking cascade mechanism in to account and DTUNUC2.0 with an incident energy of 200 A GeV. The mean multiplicity of black particles (N b ) increases with the number of grey particle N g up to 10 and then exhibits a saturation for peripheral, central and mini-bias events; the average values of grey particles g > (heavy track producing particles h > increase with increasing values of black particle N b (grey particle N g )

  15. LHCB Searches for long-lived heavy particles at LHCb

    CERN Multimedia

    Marin Benito, Carla

    2014-01-01

    Its forward acceptance and good resolution allow LHCb to perform competitive searches for heavy particles beyond the Standard Model. We report a search for the stau particle with the LHCb detector and give our prospects for searches of Hidden Valley particles.

  16. Effect of heavy charged particles of galactic cosmic radiation on seeds

    International Nuclear Information System (INIS)

    Maksimova, E.N.

    1985-01-01

    The experiments were carried out on Lactuca sativa seeds exposed for 20, 66, 123 and 308 days in a biostack also containing physical detectors of heavy charged particles. The puppose of the experiments was to measure the yield of abberrant cells and its dependence on the exposure time and the site where particles hit the object. The cytogenetic examination demonstrated a significant difference between the seeds that were or were not hit by heavy charged particles. This is indicative of a significant contribution of galactic cosmic radiation to the radiobiological effect. The yield of aberrant cells as a function of the localization of heavy charged particles in the seed was established. The most sensitive target was the root meristem

  17. Radiation chemistry of heavy-particle tracks. I. General considerations

    International Nuclear Information System (INIS)

    Magee, J.L.; Chatterjee, A.

    1980-01-01

    The radiation chemistry of heavy-particle tracks in dilute aqueous solution is considered in a unified manner. Emphasis is on the physical and chemical phenomena which are involved rather than on the construction of models to be used in actual calculations although the latter problem is discussed. A differential segment of a heavy-particle track is composed of two parts which we call core and penumbra; elementary considerations show that all properties of such a differential track can be uniquely specified in terms of a two-parameter system, and we choose energy per nucleon (E) and atomic numbers (Z) as independent parameters. The nature of heavy-particle-track processes varies with the magnitude of the energy deposit (LET), and we discuss three categories of track problems, for low-, intermediate-, and high-LET cases, respectively. Scavenger reactions normally terminate radical recombination in a track, and for heavy-particle tracks we find a criterion involving the scavenger concentration for a convenient separation of core and penumbra into essentially noninteracting parts which can be treated independently. Problems of the core expansion in the three regions are considered, and it is found that a versatile model can be constructed on concepts previously introduced by Ganguly and Magee. A model for the penumbra, based on the authors' electron-track theory, is presented and discussed

  18. Visualisation of γH2AX Foci Caused by Heavy Ion Particle Traversal; Distinction between Core Track versus Non-Track Damage

    Science.gov (United States)

    Nakajima, Nakako Izumi; Brunton, Holly; Watanabe, Ritsuko; Shrikhande, Amruta; Hirayama, Ryoichi; Matsufuji, Naruhiro; Fujimori, Akira; Murakami, Takeshi; Okayasu, Ryuichi; Jeggo, Penny; Shibata, Atsushi

    2013-01-01

    Heavy particle irradiation produces complex DNA double strand breaks (DSBs) which can arise from primary ionisation events within the particle trajectory. Additionally, secondary electrons, termed delta-electrons, which have a range of distributions can create low linear energy transfer (LET) damage within but also distant from the track. DNA damage by delta-electrons distant from the track has not previously been carefully characterised. Using imaging with deconvolution, we show that at 8 hours after exposure to Fe (∼200 keV/µm) ions, γH2AX foci forming at DSBs within the particle track are large and encompass multiple smaller and closely localised foci, which we designate as clustered γH2AX foci. These foci are repaired with slow kinetics by DNA non-homologous end-joining (NHEJ) in G1 phase with the magnitude of complexity diminishing with time. These clustered foci (containing 10 or more individual foci) represent a signature of DSBs caused by high LET heavy particle radiation. We also identified simple γH2AX foci distant from the track, which resemble those arising after X-ray exposure, which we attribute to low LET delta-electron induced DSBs. They are rapidly repaired by NHEJ. Clustered γH2AX foci induced by heavy particle radiation cause prolonged checkpoint arrest compared to simple γH2AX foci following X-irradiation. However, mitotic entry was observed when ∼10 clustered foci remain. Thus, cells can progress into mitosis with multiple clusters of DSBs following the traversal of a heavy particle. PMID:23967070

  19. Plasma polymer-functionalized silica particles for heavy metals removal.

    Science.gov (United States)

    Akhavan, Behnam; Jarvis, Karyn; Majewski, Peter

    2015-02-25

    Highly negatively charged particles were fabricated via an innovative plasma-assisted approach for the removal of heavy metal ions. Thiophene plasma polymerization was used to deposit sulfur-rich films onto silica particles followed by the introduction of oxidized sulfur functionalities, such as sulfonate and sulfonic acid, via water-plasma treatments. Surface chemistry analyses were conducted by X-ray photoelectron spectroscopy and time-of-flight secondary ion mass spectroscopy. Electrokinetic measurements quantified the zeta potentials and isoelectric points (IEPs) of modified particles and indicated significant decreases of zeta potentials and IEPs upon plasma modification of particles. Plasma polymerized thiophene-coated particles treated with water plasma for 10 min exhibited an IEP of less than 3.5. The effectiveness of developed surfaces in the adsorption of heavy metal ions was demonstrated through copper (Cu) and zinc (Zn) removal experiments. The removal of metal ions was examined through changing initial pH of solution, removal time, and mass of particles. Increasing the water plasma treatment time to 20 min significantly increased the metal removal efficiency (MRE) of modified particles, whereas further increasing the plasma treatment time reduced the MRE due to the influence of an ablation mechanism. The developed particulate surfaces were capable of removing more than 96.7% of both Cu and Zn ions in 1 h. The combination of plasma polymerization and oxidative plasma treatment is an effective method for the fabrication of new adsorbents for the removal of heavy metals.

  20. Biological effects of heavy particles

    International Nuclear Information System (INIS)

    Sabatier, L.; Martins, B.; Dutrillaux, B.

    1991-01-01

    The usual definitions of biological dose and biological dosimetry do not fit in case of particles with high linear energy transfer (LET). The dose corresponds to an average value which is not representative of the highly localized energy transfer due to heavy ions. Fortunately, up to now, a biological dosimetry following an exposure to high LET particles is necessary only for cosmonauts. In radiotherapy applications, one exactly knows the nature and energy of incident particle beams. The quality requirements for a good biodosimeter include reliable relation between dose and effect, weak sensitivity to individual variations, reliability and stability of acquired informations against the time delay between exposure and measurements. Nothing is better than the human lymphocyte to be used for measurements that fulfil these requirements. In the case of a manned spaceship, the irradiation dose corresponds to a wide range of radiation (protons, neutrons, heavy ions), and making a dosimetry as well as defining it are of current concern. As yet, there exist two possible definitions, which reduce the dose either to a proton or to a neutron equivalent one. However, such an approximation is not a faithful representation of the irradiation effects and in particular, the long-term effects may be quite different. In the future, it is reasonable to expect an evolution towards technics that enable identifying irradiated cells and quantifying precisely their radiation damage in order to reconstruct the spectrum of particles received by a given cosmonaut in a given time. Let us emphasize that the radiation hazards due to a short stay in space are quite minor, but in the case of a travel to Mars, they cannot be neglected [fr

  1. A facility for low energy charged particle induced reaction studies

    International Nuclear Information System (INIS)

    Vilaithong, T.; Singkarat, S.; Yu, L.D.; Intarasiri, S.; Tippawan, U.

    2000-01-01

    In Chiang Mai, a highly stable low energy ion accelerator (0 - 350 kV) facility is being established. A subnano-second pulsing system will be incorporated into the beam transport line. The detecting system will consist of a time-of-flight charged particle spectrometer and a high resolution gamma-ray system. The new facility will be used in the studies of low energy heavy ion backscattering and charged particle induced cross section measurement in the interests of material characterization and nucleosynthesis. (author)

  2. Long-term changes in amphetamine-induced reinforcement and aversion in rats following exposure to 56Fe particle

    Science.gov (United States)

    Rabin, B. M.; Joseph, J. A.; Shukitt-Hale, B.

    Exposing rats to heavy particles produces alterations in the functioning of dopaminergic neurons and in the behaviors that depend upon the integrity of the dopaminergic system. Two of these dopamine-dependent behaviors include amphetamine-induced reinforcement, measure using the conditioned place preference procedure, and amphetamine-induced reinforcement, measured using the conditioned place preference procedure, and amphetamine-induced aversion, measured using the conditioned taste aversion. Previous research has shown that exposing rats to 1.0 Gy of 1GeV/n 56Fe particles produced a disruption of an amphetamine-induced taste aversion 3 days following exposure, but produced an apparent enhancement of the aversion 112 days following exposure. The present experiments were designed to provide a further evaluation of these results by examining taste aversion learning 154 days following exposure to 1.0Gy 56Fe particles and to establish the convergent validity of the taste aversion results by looking at the effects of exposure on the establishment of an amphetamine-induced conditioned place preference 3, 7, and 16 weeks following irradiation. The taste aversion results failed to confirm the apparent enhancement of the amphetamine-induced CTA observed in the prior experiment. However, exposure to 56Fe particles prevented the acquisition of amphetamine-induced place preference at all three-time intervals. The results are interpreted as indicating that exposure to heavy particles can produce long-term changes in behavioral functioning.

  3. Slow, target associated particles produced in ultrarelativistic heavy-ion interactions

    Energy Technology Data Exchange (ETDEWEB)

    Adamovich, M I; Aggarwal, M M; Alexandrov, Y A; Andreeva, N P; Anson, Z V; Arora, R; Avetyan, F A; Badyal, S K; Basova, E; Bhalla, K B; Bhasin, A; Bhatia, V S; Bogdanov, V G; Bubnov, V I; Burnett, T H; Cai, X; Chasnikov, I Y; Chernova, L P; Chernyavsky, M M; Dressel, B; Eligbaeva, G Z; Eremenko, L E; Friedlander, E M; Gaitinov, A S; Ganssauge, E R; Garpman, S; Gerassimov, S G; Grote, J; Gulamov, K G; Gupta, S K; Gupta, V; Heckman, H H; Huang, H; Jakobsson, B; Judek, B; Kachroo, S; Kadyrov, F G; Kalyachkina, G S; Kanygina, E K; Karabova, M; Kaul, G L; Kaur, M; Kharlamov, S P; Koss, Y; Krasnov,; Kumar,; Lal, P; Larionova,; Lepetan,; Lindstrom,; Liu,; Lokanathan, S; Lord, J; Lukicheva, N S; Luo, S B; Mangotra, L K; Marutyan,; Maslennikova, N V; Mittra, I S; Mookerjee, S; Mueller, C; Nasrulaeva, H; Nasyrov, S H; Navotny, V S; Orlova, G I; Otterlund, I; Palsania, H S; Peresadko, N G; Petrov, N V; Plyushchev, V A; Qian, W Y; Raniwala,; EMU01 Collaboration

    1991-06-20

    The slow, target associated particles produced in ultrarelativistic heavy-ion interactions are a quantitative probe of the cascading processes in the spectator parts of the target nucleus. These processes are directly influenced by the proper timescale for the formation of hadronic matter. In this letter we show experimental data on singly and multiply charged particles, with velocities smaller than 0.7c, produced in ultrarelativistic heavy-ion interactions in nuclear emulsion. (orig.).

  4. Multiple photon emission in heavy particle decays

    International Nuclear Information System (INIS)

    Asakimori, K.; Burnett, T.H.; Cherry, M.L.

    1994-03-01

    Cosmic ray interactions, at energies above 1 TeV/nucleon, in emulsion chambers flown on high altitude balloons have yielded two events showing apparent decays of a heavy particle into one charged particle and four photons. The photons converted into electron pairs very close to the decay vertex. Attempts to explain this decay topology with known particle decays are presented. Unless both events represent a b → u transition, which is statistically unlikely, then other known decay modes for charmed or bottom particles do not account satisfactorily for these observations. This could indicate, possibly, a new decay channel. (author). 7 refs, 6 figs, 2 tabs

  5. Soot particulate size characterisation in a heavy-duty diesel engine for different engine loads by laser-induced incandescence

    NARCIS (Netherlands)

    Bougie, B.; Ganippa, L.C.; Vliet, van A.P.; Meerts, W.L.; Dam, N.J.; Meulen, ter J.J.

    2007-01-01

    Time-resolved laser-induced incandescence was used to estimate primary particle size distributions inside the combustion chamber of a heavy-duty diesel engine as a function of the crank angle, for two different engine loads at two different probe locations. Assuming a log-normal particle size

  6. Development of general-purpose particle and heavy ion transport monte carlo code

    International Nuclear Information System (INIS)

    Iwase, Hiroshi; Nakamura, Takashi; Niita, Koji

    2002-01-01

    The high-energy particle transport code NMTC/JAM, which has been developed at JAERI, was improved for the high-energy heavy ion transport calculation by incorporating the JQMD code, the SPAR code and the Shen formula. The new NMTC/JAM named PHITS (Particle and Heavy-Ion Transport code System) is the first general-purpose heavy ion transport Monte Carlo code over the incident energies from several MeV/nucleon to several GeV/nucleon. (author)

  7. Radiobiology of heavy charged particles

    International Nuclear Information System (INIS)

    Kraft, G.

    1996-11-01

    The increase in the biological efficiency is the major motivation to use ions heavier than protons for therapy. Therefore, the detailed understanding of the radiobiological potential of heavy ions like carbon or oxygen is the basic condition of a proper application of these ions in therapy. But also for the lightest ion, the proton, evidence accumulates that changes in the radiobiological properties at the end of the particle range influence the therapeutic effect. Compared to sparsely ionizing radiation heavy charged particles exhibit a different physical interaction with the target material: The highly charged ions interact mostly via Coulomb forces with the electrons of the target material producing a track of ionizations and highly kinetic electrons along the path of the primary ion. In these tracks damage to the biological structures like the DNA occurs in a non stochastic, but spatially correlated way yielding a dramatic variation in the biological severity of the created damage. In cell-experiments the variation in the relative biological efficiency has been measured for many biological reactions like cell inactivation, chromosome aberrations and DNA damage. An overview on the inactivation data will be given and theoretical approaches will be discussed and compared to experimental data. (orig.)

  8. Treatment of cancer with heavy charged particles

    International Nuclear Information System (INIS)

    Castro, J.R.

    1981-01-01

    The clinical radiotherapy trial has accured 243 patients irradiated with particles and 13 patients irradiated as controls in randomized studies. Of the 243 particle patients, 194 have been treated with helium ions, either solely or in combination with photon irradiation, and 49 have received all or part of their irradiation with one of the heavier particles, either carbon, neon, or argon ions. The project thus can be divided into two general phases: (1) evaluation of improved dose distribution without significant biologic advantage by use of helium ion irradiation; and (2) evaluation of improved dose distribution and enhanced biologic effect by irradiation with heavy charged particles such as carbon, neon, and argon ions

  9. Radiation induced muscositis as space flight risk. Model studies on X-ray and heavy ion irradiated typical oral mucosa models

    International Nuclear Information System (INIS)

    Tschachojan, Viktoria

    2014-01-01

    Humans in exomagnetospheric space are exposed to highly energetic heavy ion radiation which can be hardly shielded. Since radiation-induced mucositis constitutes a severe complication of heavy ion radiotherapy, it would also implicate a serious medical safety risk for the crew members during prolonged space flights such as missions to Moon or Mars. For assessment of risk developing radiation-induced mucositis, three-dimensional organotypic cultures of immortalized human keratinocytes and fibroblasts were irradiated with a 12 C particle beam at high energies or X-Rays. Immunofluorescence stainings were done from cryosections and radiation induced release of cytokines and chemokines was quantified by ELISA from culture supernatants. The major focuses of this study were on 4, 8, 24 and 48 hours after irradiation. The conducted analyses of our mucosa model showed many structural similarities with the native oral mucosa and authentic immunological responses to radiation exposure. Quantification of the DNA damage in irradiated mucosa models revealed about twice as many DSB after heavy-ion irradiation compared to X-rays at definite doses and time points, suggesting a higher gene toxicity of heavy ions. Nuclear factor κB activation was observed after treatment with X-rays or 12 C particles. An activation of NF κB p65 in irradiated samples could not be detected. ELISA analyses showed significantly higher interleukin 6 and interleukin 8 levels after irradiation with X-rays and 12 C particles compared to non-irradiated controls. However, only X-rays induced significantly higher levels of interleukin 1β. Analyses of TNF-α and IFN-γ showed no radiation-induced effects. Further analyses revealed a radiation-induced reduction in proliferation and loss of compactness in irradiated oral mucosa model, which would lead to local lesions in vivo. In this study we revealed that several pro-inflammatory markers and structural changes are induced by X-rays and heavy-ion irradiation

  10. Radiobiology with heavy charged particles: a historical review

    International Nuclear Information System (INIS)

    Skarsgard, L.D.

    1997-01-01

    The presentation will attempt to briefly review some of radiobiological data on the effects of heavy charged particles and to discuss the influence of those studies on the clinical application which followed. (orig./MG)

  11. Radiobiology with heavy charged particles: a historical review

    Energy Technology Data Exchange (ETDEWEB)

    Skarsgard, L D [Dept. of Medical Biophysics, B.C. Cancer Research Centre and TRIUMF, Vancouver (Canada)

    1997-09-01

    The presentation will attempt to briefly review some of radiobiological data on the effects of heavy charged particles and to discuss the influence of those studies on the clinical application which followed. (orig./MG)

  12. Description of current pulses induced by heavy ions in silicon detectors (II)

    Energy Technology Data Exchange (ETDEWEB)

    Hamrita, H. [Institut de Physique Nucleaire, CNRS/IN2P3, Universite Paris-Sud 11, F-91406 Orsay Cedex (France); CEA, LIST, Laboratoire Capteurs et Architectures Electroniques, F-91191 Gif-sur-Yvette Cedex (France); Parlog, M. [LPC, CNRS/IN2P3, ENSICAEN, Universite de Caen, F-14050 Caen Cedex (France); National Institute for Physics and Nuclear Engineering, RO-76900 Bucharest-Magurele (Romania); Borderie, B., E-mail: borderie@ipno.in2p3.fr [Institut de Physique Nucleaire, CNRS/IN2P3, Universite Paris-Sud 11, F-91406 Orsay Cedex (France); Lavergne, L. [Institut de Physique Nucleaire, CNRS/IN2P3, Universite Paris-Sud 11, F-91406 Orsay Cedex (France); Le Neindre, N. [Institut de Physique Nucleaire, CNRS/IN2P3, Universite Paris-Sud 11, F-91406 Orsay Cedex (France); LPC, CNRS/IN2P3, ENSICAEN, Universite de Caen, F-14050 Caen Cedex (France); Rivet, M.F.; Barbey, S. [Institut de Physique Nucleaire, CNRS/IN2P3, Universite Paris-Sud 11, F-91406 Orsay Cedex (France); Bougault, R. [LPC, CNRS/IN2P3, ENSICAEN, Universite de Caen, F-14050 Caen Cedex (France); Chabot, M. [Inst. de Physique Nucleaire, CNRS/IN2P3, Universite Paris-Sud 11, F-91406 Orsay Cedex (France); Chbihi, A. [GANIL (DSM-CEA/CNRS/IN2P3), F-14076 Caen Cedex (France); Cussol, D. [LPC, CNRS/IN2P3, ENSICAEN, Univ. de Caen, F-14050 Caen Cedex (France); Oliveira Santos, F. de [GANIL (DSM-CEA/CNRS/IN2P3), F-14076 Caen Cedex (France); Edelbruck, P. [Inst. de Physique Nucleaire, CNRS/IN2P3, Univ. Paris-Sud 11, F-91406 Orsay Cedex (France); Frankland, J.D. [GANIL (DSM-CEA/CNRS/IN2P3), F-14076 Caen Cedex (France); Galichet, E. [Inst. de Physique Nucleaire, CNRS/IN2P3, Univ. Paris-Sud 11, F-91406 Orsay Cedex (France); Conservatoire National des Arts et Metier, F-75141 Paris Cedex 03 (France); Guinet, D.; Lautesse, Ph. [Inst. de Physique Nucleaire, CNRS/IN2P3, Univ.e Claude Bernard Lyon I, F-69622 Villeurbanne Cedex (France); Lopez, O. [LPC, CNRS/IN2P3, ENSICAEN, Univ. de Caen, F-14050 Caen Cedex (France)

    2011-06-21

    Current pulses induced in a silicon detector by 10 different heavy ion species at known energies around 10 A MeV have been sampled in time at high frequency. Their individual average shapes are quite well reproduced by a fit procedure based on our recent charge carrier collection treatment which considers the progressive extraction of the electrons and holes from the high carrier density zone along the ionizing particle track. This region is assumed to present a supplementary dielectric polarization and consequently a disturbed electric field. The influence of the nature of the heavy ion on the values of the three fit parameters is analyzed.

  13. Productive interactions: heavy particles and non-Gaussianity

    International Nuclear Information System (INIS)

    Flauger, Raphael; Mirbabayi, Mehrdad; Senatore, Leonardo; Silverstein, Eva

    2017-01-01

    We analyze the shape and amplitude of oscillatory features in the primordial power spectrum and non-Gaussianity induced by periodic production of heavy degrees of freedom coupled to the inflaton φ. We find that non-adiabatic production of particles can contribute effects which are detectable or constrainable using cosmological data even if their time-dependent masses are always heavier than the scale φ̇ 1/2 , much larger than the Hubble scale. This provides a new role for UV completion, consistent with the criteria from effective field theory for when heavy fields cannot be integrated out. This analysis is motivated in part by the structure of axion monodromy, and leads to an additional oscillatory signature in a subset of its parameter space. At the level of a quantum field theory model that we analyze in detail, the effect arises consistently with radiative stability for an interesting window of couplings up to of order ∼< 1. The amplitude of the bispectrum and higher-point functions can be larger than that for Resonant Non-Gaussianity, and its signal/noise may be comparable to that of the corresponding oscillations in the power spectrum (and even somewhat larger within a controlled regime of parameters). Its shape is distinct from previously analyzed templates, but was partly motivated by the oscillatory equilateral searches performed recently by the Planck collaboration. We also make some general comments about the challenges involved in making a systematic study of primordial non-Gaussianity.

  14. Productive interactions: heavy particles and non-Gaussianity

    Energy Technology Data Exchange (ETDEWEB)

    Flauger, Raphael [Department of Physics, The University of Texas at Austin, Austin, TX, 78712 (United States); Mirbabayi, Mehrdad [Institute for Advanced Study, Princeton, NJ 08540 (United States); Senatore, Leonardo; Silverstein, Eva, E-mail: flauger@physics.ucsd.edu, E-mail: mehrdadm@ias.edu, E-mail: senatore@stanford.edu, E-mail: evas@slac.stanford.edu [Stanford Institute for Theoretical Physics, Stanford University, Stanford, CA 94305 (United States)

    2017-10-01

    We analyze the shape and amplitude of oscillatory features in the primordial power spectrum and non-Gaussianity induced by periodic production of heavy degrees of freedom coupled to the inflaton φ. We find that non-adiabatic production of particles can contribute effects which are detectable or constrainable using cosmological data even if their time-dependent masses are always heavier than the scale φ̇{sup 1/2}, much larger than the Hubble scale. This provides a new role for UV completion, consistent with the criteria from effective field theory for when heavy fields cannot be integrated out. This analysis is motivated in part by the structure of axion monodromy, and leads to an additional oscillatory signature in a subset of its parameter space. At the level of a quantum field theory model that we analyze in detail, the effect arises consistently with radiative stability for an interesting window of couplings up to of order ∼< 1. The amplitude of the bispectrum and higher-point functions can be larger than that for Resonant Non-Gaussianity, and its signal/noise may be comparable to that of the corresponding oscillations in the power spectrum (and even somewhat larger within a controlled regime of parameters). Its shape is distinct from previously analyzed templates, but was partly motivated by the oscillatory equilateral searches performed recently by the Planck collaboration. We also make some general comments about the challenges involved in making a systematic study of primordial non-Gaussianity.

  15. Universal behavior of charged particle production in heavy ion collisions

    Science.gov (United States)

    Phobos Collaboration; Steinberg, Peter A.; Back, B. B.; Baker, M. D.; Barton, D. S.; Betts, R. R.; Ballintijn, M.; Bickley, A. A.; Bindel, R.; Budzanowski, A.; Busza, W.; Carroll, A.; Decowski, M. P.; Garcia, E.; George, N.; Gulbrandsen, K.; Gushue, S.; Halliwell, C.; Hamblen, J.; Heintzelman, G. A.; Henderson, C.; Hofman, D. J.; Hollis, R. S.; Hołński, R.; Holzman, B.; Iordanova, A.; Johnson, E.; Kane, J. L.; Katzy, J.; Khan, N.; Kucewicz, W.; Kulinich, P.; Kuo, C. M.; Lin, W. T.; Manly, S.; McLeod, D.; Michałowski, J.; Mignerey, A. C.; Nouicer, R.; Olszewski, A.; Pak, R.; Park, I. C.; Pernegger, H.; Reed, C.; Remsberg, L. P.; Reuter, M.; Roland, C.; Roland, G.; Rosenberg, L.; Sagerer, J.; Sarin, P.; Sawicki, P.; Skulski, W.; Steadman, S. G.; Steinberg, P.; Stephans, G. S. F.; Stodulski, M.; Sukhanov, A.; Tang, J.-L.; Teng, R.; Trzupek, A.; Vale, C.; van Nieuwenhuizen, G. J.; Verdier, R.; Wadsworth, B.; Wolfs, F. L. H.; Wosiek, B.; Woźniak, K.; Wuosmaa, A. H.; Wysłouch, B.

    2003-03-01

    The PHOBOS experiment at RHIC has measured the multiplicity of primary charged particles as a function of centrality and pseudorapidity in Au+Au collisions at sqrt(s_NN) = 19.6, 130 and 200 GeV. Two kinds of universal behavior are observed in charged particle production in heavy ion collisions. The first is that forward particle production, over a range of energies, follows a universal limiting curve with a non-trivial centrality dependence. The second arises from comparisons with pp/pbar-p and e+e- data. N_tot/(N_part/2) in nuclear collisions at high energy scales with sqrt(s) in a similar way as N_tot in e+e- collisions and has a very weak centrality dependence. This feature may be related to a reduction in the leading particle effect due to the multiple collisions suffered per participant in heavy ion collisions.

  16. Current signal of silicon detectors facing charged particles and heavy ions

    International Nuclear Information System (INIS)

    Hamrita, H.

    2005-07-01

    This work consisted in collecting and studying for the first time the shapes of current signals obtained from charged particles or heavy ions produced by silicon detectors. The document is divided into two main parts. The first consisted in reducing the experimental data obtained with charged particles as well as with heavy ions. These experiments were performed at the Orsay Tandem and at GANIL using LISE. These two experiments enabled us to create a data base formed of current signals with various shapes and various times of collection. The second part consisted in carrying out a simulation of the current signals obtained from the various ions. To obtain this simulation we propose a new model describing the formation of the signal. We used the data base of the signals obtained in experiments in order to constrain the three parameters of our model. In this model, the charge carriers created are regarded as dipoles and their density is related to the dielectric polarization in the silicon detector. This phenomenon induces an increase in permittivity throughout the range of the incident ion and consequently the electric field between the electrodes of the detector is decreased inside the trace. We coupled with this phenomenon a dissociation and extraction mode of the charge carriers so that they can be moved in the electric field. (author)

  17. Particle morphology and mineral structure of heavy metal-contaminated kaolin soil before and after electrokinetic remediation.

    Science.gov (United States)

    Roach, Nicole; Reddy, Krishna R; Al-Hamdan, Ashraf Z

    2009-06-15

    This study aims to characterize the physical distribution of heavy metals in kaolin soil and the chemical and structural changes in kaolinite minerals that result from electrokinetic remediation. Three bench-scale electrokinetic experiments were conducted on kaolin that was spiked with Cr(VI) alone, Ni (II) alone, and a combination of Cr(VI), Ni(II) and Cd(II) under a constant electric potential of 1VDC/cm for a total duration of 4 days. Transmission electron microscopy (TEM), energy dispersive X-ray spectroscopy (EDX), and X-ray diffraction (XRD) analyses were performed on the soil samples before and after electrokinetic remediation. Results showed that the heavy metal contaminant distribution in the soil samples was not observable using TEM and EDX. EDX detected nickel and chromium on some kaolinite particles and titanium-rich, high-contrast particles, but no separate phases containing the metal contaminants were detected. Small amounts of heavy metal contaminants that were detected by EDX in the absence of a visible phase suggest that ions are adsorbed to kaolinite particle surfaces as a thin coating. There was also no clear correlation between semiquantitative analysis of EDX spectra and measured total metal concentrations, which may be attributed to low heavy metal concentrations and small size of samples used. X-ray diffraction analyses were aimed to detect any structural changes in kaolinite minerals resulting from EK. The diffraction patterns showed a decrease in peak height with decreasing soil pH value, which indicates possible dissolution of kaolinite minerals during electrokinetic remediation. Overall this study showed that the changes in particle morphology were found to be insignificant, but a relationship was found between the crystallinity of kaolin and the pH changes induced by the applied electric potential.

  18. Particle morphology and mineral structure of heavy metal-contaminated kaolin soil before and after electrokinetic remediation

    International Nuclear Information System (INIS)

    Roach, Nicole; Reddy, Krishna R.; Al-Hamdan, Ashraf Z.

    2009-01-01

    This study aims to characterize the physical distribution of heavy metals in kaolin soil and the chemical and structural changes in kaolinite minerals that result from electrokinetic remediation. Three bench-scale electrokinetic experiments were conducted on kaolin that was spiked with Cr(VI) alone, Ni (II) alone, and a combination of Cr(VI), Ni(II) and Cd(II) under a constant electric potential of 1 VDC/cm for a total duration of 4 days. Transmission electron microscopy (TEM), energy dispersive X-ray spectroscopy (EDX), and X-ray diffraction (XRD) analyses were performed on the soil samples before and after electrokinetic remediation. Results showed that the heavy metal contaminant distribution in the soil samples was not observable using TEM and EDX. EDX detected nickel and chromium on some kaolinite particles and titanium-rich, high-contrast particles, but no separate phases containing the metal contaminants were detected. Small amounts of heavy metal contaminants that were detected by EDX in the absence of a visible phase suggest that ions are adsorbed to kaolinite particle surfaces as a thin coating. There was also no clear correlation between semiquantitative analysis of EDX spectra and measured total metal concentrations, which may be attributed to low heavy metal concentrations and small size of samples used. X-ray diffraction analyses were aimed to detect any structural changes in kaolinite minerals resulting from EK. The diffraction patterns showed a decrease in peak height with decreasing soil pH value, which indicates possible dissolution of kaolinite minerals during electrokinetic remediation. Overall this study showed that the changes in particle morphology were found to be insignificant, but a relationship was found between the crystallinity of kaolin and the pH changes induced by the applied electric potential.

  19. Investigation of electrically-active deep levels in single-crystalline diamond by particle-induced charge transient spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Kada, W., E-mail: kada.wataru@gunma-u.ac.jp [Faculty of Science and Technology, Gunma University, Kiryu, Gunma 376-8515 (Japan); Kambayashi, Y.; Ando, Y. [Faculty of Science and Technology, Gunma University, Kiryu, Gunma 376-8515 (Japan); Japan Atomic Energy Agency, Takasaki, Gunma 370-1292 (Japan); Onoda, S. [Japan Atomic Energy Agency, Takasaki, Gunma 370-1292 (Japan); Umezawa, H.; Mokuno, Y. [National Institute of Advanced Industrial Science and Technology (AIST), 1-8-31 Midorigaoka, Ikeda, Osaka 563-8577 (Japan); Shikata, S. [Kwansei Gakuin Univ., 2-1, Gakuen, Mita, Hyogo 669-1337 (Japan); Makino, T.; Koka, M. [Japan Atomic Energy Agency, Takasaki, Gunma 370-1292 (Japan); Hanaizumi, O. [Faculty of Science and Technology, Gunma University, Kiryu, Gunma 376-8515 (Japan); Kamiya, T.; Ohshima, T. [Japan Atomic Energy Agency, Takasaki, Gunma 370-1292 (Japan)

    2016-04-01

    To investigate electrically-active deep levels in high-resistivity single-crystalline diamond, particle-induced charge transient spectroscopy (QTS) techniques were performed using 5.5 MeV alpha particles and 9 MeV carbon focused microprobes. For unintentionally-doped (UID) chemical vapor deposition (CVD) diamond, deep levels with activation energies of 0.35 eV and 0.43 eV were detected which correspond to the activation energy of boron acceptors in diamond. The results suggested that alpha particle and heavy ion induced QTS techniques are the promising candidate for in-situ investigation of deep levels in high-resistivity semiconductors.

  20. Repulsive four-body interactions of α particles and quasistable nuclear α -particle condensates in heavy self-conjugate nuclei

    Science.gov (United States)

    Bai, Dong; Ren, Zhongzhou

    2018-05-01

    We study the effects of repulsive four-body interactions of α particles on nuclear α -particle condensates in heavy self-conjugate nuclei using a semianalytic approach, and find that the repulsive four-body interactions could decrease the critical number of α particles, beyond which quasistable α -particle condensate states can no longer exist, even if these four-body interactions make only tiny contributions to the total energy of the Hoyle-like state of 16O. Explicitly, we study eight benchmark parameter sets, and find that the critical number Ncr decreases by |Δ Ncr|˜1 -4 from Ncr˜11 with vanishing four-body interactions. We also discuss the effects of four-body interactions on energies and radii of α -particle condensates. Our study can be useful for future experiments to study α -particle condensates in heavy self-conjugate nuclei. Also, the experimental determination of Ncr will eventually help establish a better understanding on the α -particle interactions, especially the four-body interactions.

  1. Understanding of the mechanical and structural changes induced by alpha particles and heavy ions in the French simulated nuclear waste glass

    International Nuclear Information System (INIS)

    Karakurt, G.; Abdelouas, A.; Guin, J.-P.; Nivard, M.; Sauvage, T.; Paris, M.; Bardeau, J.-F.

    2016-01-01

    Borosilicate glasses are considered for the long-term confinement of high-level nuclear wastes. External irradiations with 1 MeV He + ions and 7 MeV Au 5+ ions were performed to simulate effects produced by alpha particles and by recoil nuclei in the simulated SON68 nuclear waste glass. To better understand the structural modifications, irradiations were also carried out on a 6-oxides borosilicate glass, a simplified version of the SON68 glass (ISG glass). The mechanical and macroscopic properties of the glasses were studied as function of the deposited electronic and nuclear energies. Alpha particles and gold ions induced a volume change up to −0.7% and −2.7%, respectively, depending on the glass composition. Nano-indentations tests were used to determine the mechanical properties of the irradiated glasses. A decrease of about −22% to −38% of the hardness and a decrease of the reduced Young's modulus by −8% were measured after irradiations. The evolution of the glass structure was studied by Raman spectroscopy, and also 11 B and 27 Al Nuclear Magnetic Resonance (MAS-NMR) on a 20 MeV Kr irradiated ISG glass powder. A decrease of the silica network connectivity after irradiation with alpha particles and gold ions is deduced from the structural changes observations. NMR spectra revealed a partial conversion of BO 4 to BO 3 units but also a formation of AlO 5 and AlO 6 species after irradiation with Kr ions. The relationships between the mechanical and structural changes are also discussed. - Highlights: • Mechanical and structural properties of two borosilicate glass compositions irradiated with alpha particles and heavy ions were investigated. • Both kinds of particles induced a decrease of the hardness, reduced Young's modulus and density. • Electronic and nuclear interactions are responsible for the changes observed. • The evolution of the mechanical properties under irradiation is linked to the changes occured in the

  2. Production of heavy particles by protons on protons

    International Nuclear Information System (INIS)

    Afek, Y.; Margolis, B.; Polvani, L.

    1982-01-01

    We calculate the production of heavy particles in the multi-GeV energy range using parton-model and statistical considerations. We discuss both central production and fragmentation. Our picture has implications for the question of the existence of a limiting temperature in hardron interaction

  3. Effects of heavy particle irradiation and diet on object recognition memory in rats

    Science.gov (United States)

    Rabin, Bernard M.; Carrihill-Knoll, Kirsty; Hinchman, Marie; Shukitt-Hale, Barbara; Joseph, James A.; Foster, Brian C.

    2009-04-01

    On long-duration missions to other planets astronauts will be exposed to types and doses of radiation that are not experienced in low earth orbit. Previous research using a ground-based model for exposure to cosmic rays has shown that exposure to heavy particles, such as 56Fe, disrupts spatial learning and memory measured using the Morris water maze. Maintaining rats on diets containing antioxidant phytochemicals for 2 weeks prior to irradiation ameliorated this deficit. The present experiments were designed to determine: (1) the generality of the particle-induced disruption of memory by examining the effects of exposure to 56Fe particles on object recognition memory; and (2) whether maintaining rats on these antioxidant diets for 2 weeks prior to irradiation would also ameliorate any potential deficit. The results showed that exposure to low doses of 56Fe particles does disrupt recognition memory and that maintaining rats on antioxidant diets containing blueberry and strawberry extract for only 2 weeks was effective in ameliorating the disruptive effects of irradiation. The results are discussed in terms of the mechanisms by which exposure to these particles may produce effects on neurocognitive performance.

  4. Preventive effects of running exercise on bones in heavy ion particle irradiated rats

    International Nuclear Information System (INIS)

    Fukuda, Satoshi; Iida, Haruzo; Yan, Xueming

    2002-01-01

    We examined the effects of running exercise on preventing decreases in bone mineral and tissue volume after heavy ion particle irradiation in rats. Male Wistar rats experienced whole-body irradiation by heavy ion particle beam (C-290 MeV) at doses of 0.5, 1.0, and 5.0 Gy and were divided into voluntary running groups and control groups. Rats in the running groups ran on the treadmill 15 m/mim, 90 min/day for 35 days after exposure. At the end of the experiment, a tibia was obtained from each rat for measurement of bone mineral density (BMD) and cross-sectional area, strength strain index, and bone histomorphometric analysis. The weights of muscles and concentration of serum calcium were measured. Total BMD and trabecular BMD in the metaphysis and cortical BMD of the diaphysis of tibia in the running groups increased. Bone volume and trabecular thickness increased while trabecular separation decreased in the running groups compared to those in the control groups at respective doses. However, the osteoid surface and eroded surface varied in the running groups compared to those of the respective corresponding groups. The dynamic parameters such as mineralizing surface, mineral apposition rate, and bone formation rate in the running groups were varied, probably due to the differences in radiation-induced sensitivities of bones following radiation exposure. The overall results suggest that running exercise might have a beneficial effect on preventing bone mineral loss and changes in bone structure induced by space radiation, but it is necessary to examine the optimal conditions of running exercise response to doses. (author)

  5. Coulomb ionization of inner shells by heavy charged particles

    International Nuclear Information System (INIS)

    Lapicki, G.

    1975-01-01

    The theory of inner-shell Coulomb ionization by heavy charged particles, of atomic number small compared to the target atomic number, is developed through the extension of work by Brandt and his coworkers for K shells to L shells. In slow collisions relative to the characteristic times of the inner shell electrons, the quantum-mechanical predictions in the plane-wave Born approximation (PWBA) can exceed experimental cross sections by orders of magnitude. The effects of the perturbation of the atom by and the Coulomb deflection of the particle during collisions are included in the theory. The perturbed atomic states amount to a binding of the inner-shell electrons to the moving particle in slow collisions, and to a polarization of the inner shells by the particle passing at large impact parameters during nonadiabatic collisions. These effects, not contained in the PWBA, are treated in the framework of the perturbed stationary state (PSS) theory for slow collisions and in terms of the harmonic oscillator model of Ashley, Brandt, and Ritchie for stopping powers in fast collisions. The effect of the Coulomb deflection of the particle in the field of the target nucleus on the cross sections is incorporated in the semiclassical approximation of Bang and Hansteen. Except for the lightest target atoms, the contribution of electron capture by the particles to inner-shell ionizations is shown to be negligible. The theory as developed earlier for the K shell, and here for L shells, agrees well with the vast body of experimental data on inner-shell Coulomb ionization by heavy charged particles

  6. Prediction of beauty particle masses with the heavy quark effective theory

    International Nuclear Information System (INIS)

    Aglietti, U.

    1992-01-01

    Using symmetry properties of the static theory for heavy quarks, the spectrum of beauty particles is predicted in terms of the spectrum of charmed particles. A simple technique for cancelling spin dependent corrections to the static theory is explained and systematically applied. (orig.)

  7. Adaptive response of low linear energy transfer X-rays for protection against high linear energy transfer accelerated heavy ion-induced teratogenesis.

    Science.gov (United States)

    Wang, Bing; Ninomiya, Yasuharu; Tanaka, Kaoru; Maruyama, Kouichi; Varès, Guillaume; Eguchi-Kasai, Kiyomi; Nenoi, Mitsuru

    2012-12-01

    Adaptive response (AR) of low linear energy transfer (LET) irradiations for protection against teratogenesis induced by high LET irradiations is not well documented. In this study, induction of AR by X-rays against teratogenesis induced by accelerated heavy ions was examined in fetal mice. Irradiations of pregnant C57BL/6J mice were performed by delivering a priming low dose from X-rays at 0.05 or 0.30 Gy on gestation day 11 followed one day later by a challenge high dose from either X-rays or accelerated heavy ions. Monoenergetic beams of carbon, neon, silicon, and iron with the LET values of about 15, 30, 55, and 200 keV/μm, respectively, were examined. Significant suppression of teratogenic effects (fetal death, malformation of live fetuses, or low body weight) was used as the endpoint for judgment of a successful AR induction. Existence of AR induced by low-LET X-rays against teratogenic effect induced by high-LET accelerated heavy ions was demonstrated. The priming low dose of X-rays significantly reduced the occurrence of prenatal fetal death, malformation, and/or low body weight induced by the challenge high dose from either X-rays or accelerated heavy ions of carbon, neon or silicon but not iron particles. Successful AR induction appears to be a radiation quality event, depending on the LET value and/or the particle species of the challenge irradiations. These findings would provide a new insight into the study on radiation-induced AR in utero. © 2012 Wiley Periodicals, Inc.

  8. Charged particle induced energy dispersive X-ray analysis

    International Nuclear Information System (INIS)

    Johansson, S.A.E.

    1979-01-01

    This review article deals with the X-ray emission induced by heavy, charged particles and the use of this process as an analytical method (PIXE). The physical processes involved, X-ray emission and the various reactions contributing to the background, are described in some detail. The sensitivity is calculated theoretically and the results compared with practical experience. A discussion is given on how the sensitivity can be optimized. The experimental arrangements are described and the various technical problems discussed. The analytical procedure, especially the sample preparation, is described in considerable detail. A number of typical practical applications are discussed. (author)

  9. Particle-production mechanism in relativistic heavy-ion collisions

    International Nuclear Information System (INIS)

    Bush, B.W.; Nix, J.R.

    1994-01-01

    We discuss the production of particles in relativistic heavy-ion collisions through the mechanism of massive bremsstrahlung, in which massive mesons are emitted during rapid nucleon acceleration. This mechanism is described within the framework of classical hadrodynamics for extended nucleons, corresponding to nucleons of finite size interacting with massive meson fields. This new theory provides a natural covariant microscopic approach to relativistic heavy-ion collisions that includes automatically spacetime nonlocality and retardation, nonequilibrium phenomena, interactions among all nucleons, and particle production. Inclusion of the finite nucleon size cures the difficulties with preacceleration and runaway solutions that have plagued the classical theory of self-interacting point particles. For the soft reactions that dominate nucleon-nucleon collisions, a significant fraction of the incident center-of-mass energy is radiated through massive bremsstrahlung. In the present version of the theory, this radiated energy is in the form of neutral scalar (σ) and neutral vector (ω) mesons, which subsequently decay primarily into pions with some photons also. Additional meson fields that are known to be important from nucleon-nucleon scattering experiments should be incorporated in the future, in which case the radiated energy would also contain isovector pseudoscalar (π + , π - , π 0 ), isovector scalar (δ + , δ - , δ 0 ), isovector vector (ρ + , ρ - , ρ 0 ), and neutral pseudoscalar (η) mesons

  10. Heavy particle track structure parameters for biophysical modelling

    International Nuclear Information System (INIS)

    Watt, D.E.

    1994-01-01

    Averaged values of physical track structure parameters are important in radiobiology and radiological protection for the expression of damage mechanisms and for quantifying radiation effects. To provide a ready reference, tables of relevant quantities have been compiled for heavy charged particles in liquid water. The full tables will be published elsewhere but here illustrative examples are given of the trends for the most important quantities. In the tables, data are given for 74 types of heavy charged particle ranging from protons to uranium ions at specific energies between 0.1 keV/u and 1 GeV/u. Aggregate effects in liquid water are taken into account implicitly in the calculations. Results are presented for instantaneous particle energies and for averages over the charged particle equilibrium spectrum. The latter are of special relevance to radiation dosimetry. Quality parameters calculated are: β 2 ; z 2 /β 2 ; linear primary ionisation and the mean free path between ionisations; LET; track and dose-restricted LET with 100 eV cut-off; relative variances; delta-ray energies and ranges; ion energies and ranges and kerma factors. Here, the procedures used in the calculations are indicated. Representative results are shown in graphical form. The role of the physical track properties is discussed with regard to optimisation of the design of experiments intended to elucidate biological damage mechanisms in mammalian cells and their relevance to radiological protection. ((orig.))

  11. Proceedings of the international heavy particle therapy workshop (PTCOG/EORTC/ECNEU)

    International Nuclear Information System (INIS)

    Blattmann, H.

    1990-07-01

    The International Heavy Particle Therapy Workshop at PSI was an experiment in several ways. For the PTCOG it was the first meeting outside the American continent. It was also the first meeting of PRCOG in conjunction with the EORTC Heavy Particle Therapy Group, which up to now has been dominated by discussion on neutron therapy. A common goal for radiotherapy as well as neutron therapy are all aiming at this goal by improved dose distribution and/or higher biological effectiveness. The meeting at Villigen was an attempt to stimulate discussion between the different groups and to strengthen international collaboration. The large number of proffered oral papers and posters was certainly a sign that the meeting served a need and that particle radiotherapy enjoys growing interest worldwide. 89 tabs., 164 figs., 441 refs

  12. A time of flight detector for high energy heavy particles

    Energy Technology Data Exchange (ETDEWEB)

    Fang, Z.; O`Connor, D.J. [Newcastle Univ., NSW (Australia). Dept. of Physics

    1993-12-31

    As a commonly used method to measure the energy of a particle with known mass, the flight time of the particle travelling over a certain distance is measured. A detector based on this principle is called a time-of-flight (TOF) detector which has attracted interests constantly during the last 15 years. For high energy heavy particle energy detection, TOF detector is an appropriated choice and such a system, developed recently, is described in this paper. 8 refs., 3 figs.

  13. A time of flight detector for high energy heavy particles

    Energy Technology Data Exchange (ETDEWEB)

    Fang, Z; O` Connor, D J [Newcastle Univ., NSW (Australia). Dept. of Physics

    1994-12-31

    As a commonly used method to measure the energy of a particle with known mass, the flight time of the particle travelling over a certain distance is measured. A detector based on this principle is called a time-of-flight (TOF) detector which has attracted interests constantly during the last 15 years. For high energy heavy particle energy detection, TOF detector is an appropriated choice and such a system, developed recently, is described in this paper. 8 refs., 3 figs.

  14. Specific gene mutations induced by heavy ions

    International Nuclear Information System (INIS)

    Freeling, M.; Karoly, C.W.; Cheng, D.S.K.

    1980-01-01

    This report summarizes our heavy-ion research rationale, progress, and plans for the near future. The major project involves selecting a group of maize Adh1 mutants induced by heavy ions and correlating their altered behavior with altered DNA nucleotide sequences and sequence arrangements. This research requires merging the techniques of classical genetics and recombinant DNA technology. Our secondary projects involve (1) the use of the Adh gene in the fruit fly, Drosophila melanogaster, as a second system with which to quantify the sort of specific gene mutants induced by heavy ions as compared to x rays, and (2) the development of a maize Adh1 pollen in situ monitor for environmental mutagens

  15. Heavy-ion induced desorption yields of amorphous carbon films bombarded with 4.2 MeV/u lead ions

    CERN Document Server

    Mahner, E; Küchler, D; Scrivens, R; Costa Pinto, P; Yin Vallgren, C; Bender, M

    2011-01-01

    During the past decade, intense experimental studies on the heavy-ion induced molecular desorption were performed in several particle accelerator laboratories worldwide in order to understand and overcome large dynamic pressure rises caused by lost beam ions. Different target materials and various coatings were studied for desorption and mitigation techniques were applied to heavy-ion accelerators. For the upgrade of the CERN injector complex, a coating of the Super Proton Synchrotron (SPS) vacuum system with a thin film of amorphous carbon is under study to mitigate the electron cloud effect observed during SPS operation with the nominal proton beam for the Large Hadron Collider (LHC). Since the SPS is also part of the heavy-ion injector chain for LHC, dynamic vacuum studies of amorphous carbon films are important to determine their ion induced desorption yields. At the CERN Heavy Ion Accelerator (LINAC 3), carbon-coated accelerator-type stainless steel vacuum chambers were tested for desorption using 4.2 Me...

  16. A map for heavy inertial particles in fluid flows

    Science.gov (United States)

    Vilela, Rafael D.; de Oliveira, Vitor M.

    2017-06-01

    We introduce a map which reproduces qualitatively many fundamental properties of the dynamics of heavy particles in fluid flows. These include a uniform rate of decrease of volume in phase space, a slow-manifold effective dynamics when the single parameter s (analogous of the Stokes number) approaches zero, the possibility of fold caustics in the "velocity field", and a minimum, as a function of s, of the Lyapunov (Kaplan-Yorke) dimension of the attractor where particles accumulate.

  17. Understanding of the mechanical and structural changes induced by alpha particles and heavy ions in the French simulated nuclear waste glass

    Energy Technology Data Exchange (ETDEWEB)

    Karakurt, G., E-mail: karakurt_gokhan@yahoo.fr [SUBATECH, UMR 6457CNRS-IN2P3, Ecole des Mines de Nantes, 4 rue Alfred Kastler, 44307 Nantes (France); Abdelouas, A. [SUBATECH, UMR 6457CNRS-IN2P3, Ecole des Mines de Nantes, 4 rue Alfred Kastler, 44307 Nantes (France); Guin, J.-P.; Nivard, M. [Institut de Physique de Rennes, Université de Rennes 1 – UMR 62051 IPR, 263 avenue du Général Leclerc, 35042 Rennes (France); Sauvage, T. [Laboratoire CEMHTI (Conditions Extrêmes et Matériaux: Haute Température et Irradiation), CNRS UPR, 3079 Orléans (France); Paris, M. [Institut des Matériaux Jean ROUXEL, Université de Nantes, UMR 6502 CNRS, 2 rue de la Houssinière, BP 32229, 44322 Nantes Cedex 03 (France); Bardeau, J.-F. [Institut des Molécules et Matériaux du Mans, UMR CNRS 6283, avenue Olivier Messiaen, 72085 Le Mans (France)

    2016-07-15

    Borosilicate glasses are considered for the long-term confinement of high-level nuclear wastes. External irradiations with 1 MeV He{sup +} ions and 7 MeV Au{sup 5+} ions were performed to simulate effects produced by alpha particles and by recoil nuclei in the simulated SON68 nuclear waste glass. To better understand the structural modifications, irradiations were also carried out on a 6-oxides borosilicate glass, a simplified version of the SON68 glass (ISG glass). The mechanical and macroscopic properties of the glasses were studied as function of the deposited electronic and nuclear energies. Alpha particles and gold ions induced a volume change up to −0.7% and −2.7%, respectively, depending on the glass composition. Nano-indentations tests were used to determine the mechanical properties of the irradiated glasses. A decrease of about −22% to −38% of the hardness and a decrease of the reduced Young's modulus by −8% were measured after irradiations. The evolution of the glass structure was studied by Raman spectroscopy, and also {sup 11}B and {sup 27}Al Nuclear Magnetic Resonance (MAS-NMR) on a 20 MeV Kr irradiated ISG glass powder. A decrease of the silica network connectivity after irradiation with alpha particles and gold ions is deduced from the structural changes observations. NMR spectra revealed a partial conversion of BO{sub 4} to BO{sub 3} units but also a formation of AlO{sub 5} and AlO{sub 6} species after irradiation with Kr ions. The relationships between the mechanical and structural changes are also discussed. - Highlights: • Mechanical and structural properties of two borosilicate glass compositions irradiated with alpha particles and heavy ions were investigated. • Both kinds of particles induced a decrease of the hardness, reduced Young's modulus and density. • Electronic and nuclear interactions are responsible for the changes observed. • The evolution of the mechanical properties under irradiation is linked

  18. Accelerated heavy ions induced DNA double-strand breaks in yeast cells

    International Nuclear Information System (INIS)

    Akpa, T.C.

    1993-01-01

    Yeast cells of strain cerevisiae, were irradiated with monoenergetic heavy ions, X-rays and α particles and assayed for DNA double-strand breaks and cell survival. The method of neutral sucrose gradient velocity sedimentation was used for all heavy-ion experiments because it is a well established technique.The method of pulsed-field gel electrophoresis was used for X-rays, α particles and argon ions. Results show that within the range of LET of the particles used (300 - 10 5 KeV/μm) the induction cross-section for DNA double-strand break is constant between 300 and around 7000 KeV/μm and increases at higher LET values. The inactivation cross-section follow the same trend. The DSB-induction and inactivation cross-section was shown to be linearly related with a slope of (1.01±0.15)/109 gmol-i. The RBE for DSB -induced decreases with LET and tails off at high LET values also. These results when compared with results from literature shows that the trend of induction is first monotonic rise of rate of DSB-induction up to 100keV/μm, followed by a plateau and a further rise which is due to increased effect of energetic γ-rays formed as shown for survival studies and predicted is possible to separate the cell DNA contents into 13 to 15 chromosome bands. The relative decrease in DNA content of the first band as determined by ethidium bromide-UV fluorescence decreases exponentially. The cross-section for DSB-induction determined by this method are (9.8±0.01)dsb/10 12 gmol - 1 Gy - 1, for 80 kV X-rays in haploid 211 yeast strain; (0.04+0.003)dsb/109gmol - 1μm 2 for Am-radioisotope α particles in haploid cells, (0.184±0.034) dsb/10 9 gmol - 1μm 2 in diploid 211*B cells and (0.55±0.04) dsb/10 9 gmol - 1μm 2 for 7MeV Argon ion in the diploid cells. The values are comparable to those obtained with velocity sedimentation technique. However, the reason for the low value obtained for a particle induced DSB in haploid cells is not clear

  19. Current heavy particle medical accelerator programs in Japan

    International Nuclear Information System (INIS)

    Kawachi, K.

    1987-01-01

    The first clinical trial of proton radiotherapy in Japan started at National Institute of Radiological Sciences (NIRS) in 1979. The proton which is provided from the NIRS medical cyclotron, has an energy of 70 MeV, and has been used for only superficial or short range tumor therapy. Recently, the cyclotron has been raised the energy up to 90 MeV and a vertical treatment line of protons has been completed in the basement of the cyclotron building. In 1983, Particle Radiation Medical Science Center (PARMS) of the University of Tsukuba started to treat patients with 250 MeV proton beam. The Institute of Physical and Chemical Research (IPCR) has a plan to construct a heavy ion biomedical irradiation facility in the Ring (Separate Sector) Cyclotron building. The facility will be completed in 1989 and will be used for proton and helium ion therapy. Recently, several hospitals have proposed to construct the dedicated proton therapy facilities. The National Cancer Center of Japan, and the PARMS of the University of Tsukuba have taken active parts in such projects. At present time, there is a step to make a decision of the type of accelerators. Another program is a construction of the NIRS Heavy Particle Medical Accelerator which is possible to provide Helium to Argon ions for therapy. The paper describes the accelerators for proton therapy and for heavy ion therapy in some detail

  20. Charged Particle, Photon Multiplicity, and Transverse Energy Production in High-Energy Heavy-Ion Collisions

    Directory of Open Access Journals (Sweden)

    Raghunath Sahoo

    2015-01-01

    Full Text Available We review the charged particle and photon multiplicities and transverse energy production in heavy-ion collisions starting from few GeV to TeV energies. The experimental results of pseudorapidity distribution of charged particles and photons at different collision energies and centralities are discussed. We also discuss the hypothesis of limiting fragmentation and expansion dynamics using the Landau hydrodynamics and the underlying physics. Meanwhile, we present the estimation of initial energy density multiplied with formation time as a function of different collision energies and centralities. In the end, the transverse energy per charged particle in connection with the chemical freeze-out criteria is discussed. We invoke various models and phenomenological arguments to interpret and characterize the fireball created in heavy-ion collisions. This review overall provides a scope to understand the heavy-ion collision data and a possible formation of a deconfined phase of partons via the global observables like charged particles, photons, and the transverse energy measurement.

  1. Present status and future trends of heavy particle radiotherapy

    International Nuclear Information System (INIS)

    Jones, D.T.L.

    1999-01-01

    Fast neutron therapy began as long ago as 1938 and subsequently proton, alpha particle, heavy ion, pion and neutron capture therapy have been used. To date it is estimated that in excess of 45000 people have undergone some form of particle therapy. In the future it is expected that fast neutron therapy will be used for selected tumour types for which neutrons are known to show improved cure rates. The future trends in charged particle therapy will be driven by increasing commercialization. The future of neutron capture therapy will depend on current clinical trials with epithermal neutron beams and the development of new tumour-seeking drugs. (author)

  2. Search for long-lived heavy charged particles using a ring imaging Cherenkov technique at LHCb

    NARCIS (Netherlands)

    Aaij, R.; Adeva, B.; Adinolfi, M.; Affolder, A.; Ajaltouni, Z.; Akar, S.; Albrecht, J.; Alessio, F.; Alexander, M.; Ali, S.; Alkhazov, G.; Cartelle, P. Alvarez; Alves, A. A., Jr.; Amato, S.; Amerio, S.; Amhis, Y.; Everse, LA; Anderlini, L.; Anderson, J.; Andreotti, M.; Andrews, J.E.; Appleby, R. B.; Gutierrez, O. Aquines; Archilli, F.; d'Argent, P.; Artamonov, A.; Artuso, M.; Aslanides, E.; Auriemma, G.; Baalouch, M.; Bachmann, S.; Back, J. J.; Badalov, A.; Baesso, C.; Baldini, W.; Barlow, R. J.; Barschel, C.; Barsuk, S.; Barter, W.; Batozskaya, V.; Battista, V.; Bay, A.; Beaucourt, L.; Beddow, J.; Bedeschi, F.; Bediaga, I.; Bel, L. J.; Belyaev, I.; Ben-Haim, E.; Bencivenni, G.; Benson, S.; Benton, J.; Berezhnoy, A.; Bernet, R.; Bertolin, A.; Bettler, M-O.; Van Beuzekom, Martin; Bien, A.; Bifani, S.; Bird, T.D.; Birnkraut, A.; Bizzeti, A.; Blake, T.; Blanc, F.; Blouw, J.; Blusk, S.; Bocci, V.; Bondar, A.; Bondar, N.; Bonivento, W.; Borghi, S.; Borgia, A.; Borsato, M.; Bowcock, T. J. V.; Bowen, E.; Bozzi, C.; Brett, D.; Britsch, M.; Britton, T.; Brodzicka, J.; Brook, N. H.; Bursche, A.; Buytaert, J.; Cadeddu, S.; Calabrese, R.; Calvi, M.; Calvo Gomez, M.; Campana, P.; Perez, D. H. Campora; Capriotti, L.; Carbone, A.; Carboni, G.; Cardinale, R.; Cardini, A.; Carniti, P.; Carson, L.; Carvalho Akiba, K.; Casanova Mohr, R.; Casse, G.; Cassina, L.; Garcia, L. Castillo; Cattaneo, M.; Cauet, Ch; Cavallero, G.; Cenci, R.; Charles, M.; Charpentier, Ph; Chefdeville, M.; Chen, S.; Cheung, S-F.; Chiapolini, N.; Chrzaszcz, M.; Vidal, X. Cid; Ciezarek, G.; Clarke, P. E. L.; Clemencic, M.; Cliff, H. V.; Closier, J.; Coco, V.; Cogan, J.; Cogneras, E.; Cogoni, V.; Cojocariu, L.; Collazuol, G.; Collins, P.; Comerma-Montells, A.; Contu, A.; Cook, A.; Coombes, M.; Coquereau, S.; Corti, G.; Corvo, M.; Counts, I.; Couturier, B.; Cowan, G. A.; Craik, D. C.; Crocombe, A.; CruzTorres, M.; Cunliffe, S.; Currie, C.R.; D'Ambrosio, C.; Dalseno, J.; David, P. N. Y.; Davis, A.; De Bruyn, K.; De Capua, S.; De Cian, M.; de Miranda, J. M.; Paula, L.E.; da-Silva, W.S.; De Simone, P.; Dean, C-T.; Decamp, D.; Deckenhoff, M.; Del Buono, L.; Deleage, N.; Derkach, D.; Deschamps, O.; Dettori, F.; Dey, B.; Di Canto, A.; Di Ruscio, F.; Dijkstra, H.; Donleavy, S.; Dordei, F.; Dorigo, M.; Dosil Suarez, A.; Dossett, D.; Dovbnya, A.; Dreimanis, K.; Dujany, G.; Dupertuis, F.; Durante, P.; Dzhelyadin, R.; Dziurda, A.; Dzyuba, A.; Easo, S.; Egede, U.; Egorychev, V.; Eidelman, S.; Eisenhardt, S.; Eitschberger, U.; Ekelhof, R.; Eklund, L.; ElRifai, I.; Elsasser, Ch.; Ely, S.; Esen, S.; Evans, H. M.; Evans, T. M.; Falabella, A.; Faerber, C.; Farinelli, C.; Farley, N.; Farry, S.; Fay, R.; Ferguson, D.; Fernandez Albor, V.; Ferrari, F.; Ferreira Rodrigues, F.; Ferro-Luzzi, M.; Filippov, S.; Fiore, M.; Fiorini, M.; Firlej, M.; Fitzpatrick, C.; Fiutowski, T.; Fol, P.; Fontana, Mark; Fontanelli, F.; Forty, R.; De Aguiar Francisco, O.; Frank, M.; Frei, C.; Frosini, M.; Fu, J.; Furfaro, E.; Torreira, A. Gallas; Galli, D.; Gallorini, S.; Gambetta, S.; Gandelman, M.; Gandini, P.; Gao, Y.; Garcia Pardinas, J.; Garofoli, J.; Tico, J. Garra; Garrido, L.; Gascon, D.; Carvalho-Gaspar, M.; Gauld, Rhorry; Gavardi, L.; Gazzoni, G.; Geraci, A.; Gerick, D.; Gersabeck, E.; Gersabeck, M.; Gershon, T. J.; Ghez, Ph; Gianelle, A.; Giani, S.; Gibson, V.; Giubega, L.; Gligorov, V. V.; Goebel, C.; Golubkov, D.; Golutvin, A.; Gomes, A.Q.; Gotti, C.; Gandara, M. Grabalosa; Diaz, R. Graciani; Cardoso, L. A. Granado; Grauges, E.; Graverini, E.; Graziani, G.; Grecu, A.; Greening, E.; Gregson, S.; Griffith, P.; Grillo, L.; Gruenberg, O.; Gui, B.; Gushchin, E.; Guz, Yu; Gys, T.; Hadjivasiliou, C.; Haefeli, G.; Haen, C.; Haines, S. C.; Hall, S.; Hamilton, B.; Hampson, T.; Han, X.; Hansmann-Menzemer, S.; Harnew, N.; Harnew, S. T.; Harrison, J.; He, J.; Head, T.; Heijne, V.; Hennessy, K.; Henrard, P.; Henry, L.; Hernando Morata, J. A.; van Herwijnen, E.; Hess, H.M.; Hicheur, A.; Hill, D.; Hoballah, M.; Hombach, C.; Hulsbergen, W.; Humair, T.; Hussain, N.; Hutchcroft, D. E.; Hynds, D.; Idzik, M.; Ilten, P.; Jacobsson, R.; Jaeger, A.; Jalocha, J.; Jans, E.; Jawahery, A.; Jing, F.; John, M.; Johnson, D.; Jones, C. R.; Joram, C.; Jost, B.; Jurik, N.; Kandybei, S.; Kanso, W.; Karacson, M.; Karbach, T. M.; Karodia, S.; Kelsey, M. H.; Kenyon, I. R.; Kenzie, M.; Ketel, T.; Khanji, B.; Khurewathanakul, C.; Klaver, S.M.; Klimaszewski, K.; Kochebina, O.; Kolpin, M.; Komarov, I.; Koopman, R. F.; Koppenburg, P.; Kravchuk, L.; Kreplin, K.; Kreps, M.; Krocker, G.; Krokovny, P.; Kruse, F.; Kucewicz, W.; Kucharczyk, M.; Kudryavtsev, V.; Kurek, K.; Kvaratskheliya, T.; La Thi, V. N.; Lacarrere, D.; Lafferty, G. D.; Lai, A.; Lambert, D.M.; Lambert, R. W.; Lanfranchi, G.; Langenbruch, C.; Langhans, B.; Latham, T. E.; Lazzeroni, C.; Le Gac, R.; van Leerdam, J.; Lees, J. P.; Lefevre, R.; Leflat, A.; Lefrancois, J.; Leroy, O.; Lesiak, T.; Leverington, B.; Li, Y.; Likhomanenko, T.; Liles, M.; Lindner, R.; Linn, S.C.; Lionetto, F.; Liu, B.; Lohn, S.; Longstaff, I.; Lopes, J. H.; Lucchesi, D.; Luo, H.; Lupato, A.; Luppi, E.; Lupton, O.; Machefert, F.; Machikhiliyan, I. V.; Maciuc, F.; Maev, O.; Malde, S.; Malinin, A.; Manca, G.; Mancinelli, G.; Manning, P.; Mapelli, A.; Maratas, J.; Marchand, J. F.; Marconi, U.; Marin Benito, C.; Marino, P.; Maerki, R.; Marks, J.; Martellotti, G.; Martinelli-Boneschi, F.; Santos, D. Martinez; Martinez-Vidal, F.; Martins Tostes, D.; Massafferri, A.; Matev, R.; Mathe, Z.; Matteuzzi, C.; Mauri, A.; Maurin, B.; Mazurov, A.; McCann, M.; McCarthy, J.; Mcnab, A.; McNulty, R.; McSkelly, B.; Meadows, B. T.; Meier, F.; Meissner, M.; Merk, M.; Milanes, D. A.; Minard, M. N.; Mitzel, D. S.; Molina Rodriguez, J.; Monteil, S.; Morandin, M.; Morawski, P.; Morda, A.; Morello, M. J.; Moron, J.; Morris, A. B.; Mountain, R.; Muheim, F.; Mueller, J.; Mueller, Karl; Mueller, V.; Mussini, M.; Muster, B.; Naik, P.; Nakada, T.; Nandakumar, R.; Nasteva, I.; Needham, M.; Neri, N.; Neubert, S.; Neufeld, N.; Neuner, M.; Nguyen, A. D.; Nguyen, T. D.; Nguyen-Mau, C.; Niess, V.; Niet, R.; Nikitin, N.; Nikodem, T.; Novoselov, A.; O'Hanlon, D. P.; Oblakowska-Mucha, A.; Obraztsov, V.; Ogilvy, S.; Okhrimenko, O.; Oldeman, R.; Onderwater, C. J. G.; Osorio Rodrigues, B.; Otalora Goicochea, J. M.; Otto, E.A.; Owen, R.P.; Oyanguren, A.; Palano, A.; Palombo, F.; Palutan, M.; Panman, J.; Papanestis, A.; Pappagallo, M.; Pappalardo, L.L.; Parkes, C.; Passaleva, G.; Patel, G. D.; Patel, M.; Patrignani, C.; Pearce, D.A.; Pellegrino, A.; Penso, G.; Altarelli, M. Pepe; Perazzini, S.; Perret, P.; Pescatore, L.; Petridis, K.; Petrolini, A.; Olloqui, E. Picatoste; Pietrzyk, B.; Pilar, T.; Pinci, D.; Pistone, A.; Playfer, S.; Plo Casasus, M.; Poikela, T.; Polci, F.; Poluektov, A.; Polyakov, I.; Polycarpo, E.; Popov, A.; Popov, D.; Popovici, B.; Potterat, C.; Price, M. E.; Price, J.D.; Prisciandaro, J.; Pritchard, C.A.; Prouve, C.; Pugatch, V.; Navarro, A. Puig; Punzi, G.; Qian, Y.W.; Quagliani, R.; Rachwal, B.; Rademacker, J. H.; Rakotomiaramanana, B.; Rama, M.; Rangel, M. S.; Raniuk, I.; Rauschmayr, N.; Raven, G.; Redi, F.; Reichert, S.; Reid, M.; dos Reis, A. C.; Ricciardi, S.; Richards, Jennifer S; Rihl, M.; Rinnert, K.; Rives Molina, V.; Robbe, P.; Rodrigues, A. B.; Rodrigues, L.E.T.; Perez, P. Rodriguez; Roiser, S.; Romanovsky, V.; Romero Vidal, A.; Rotondo, M.; Rouvinet, J.; Ruf, T.; Ruiz, van Hapere; Ruiz Valls, P.; Saborido Silva, J. J.; Sagidova, N.; Sail, P.; Saitta, B.; Salustino Guimaraes, V.; Sanchez Mayordomo, C.; Sanmartin Sedes, B.; Santacesaria, R.; Santamarina Rios, C.; Santovetti, E.; Sarti, A.; Satriano, C.; Satta, A.; Saunders, D. M.; Savrina, D.; Schiller, M.; Schindler, R. H.; Schlupp, M.; Schmelling, M.; Schmelzer, T.; Schmidt, B.; Schneider, O.; Schopper, A.; Schune, M. H.; Schwemmer, R.; Sciascia, B.; Sciubba, A.; Semennikov, A.; Sepp, I.; Serra, N.; Serrano, J.; Sestini, L.; Seyfert, P.; Shapkin, M.; Shapoval, I.; Shcheglov, Y.; Shears, T.; Shekhtman, L.; Shevchenko, V.; Shires, A.; Coutinho, R. Silva; Simi, G.; Sirendi, M.; Skidmore, N.; Skillicorn, I.; Skwarnicki, T.; Smith, E.; Smith, E.; Smith, J; Smith, M.; Snoek, H.; Sokoloff, M. D.; Soler, F. J. P.; Soomro, F.; de Souza, D.K.; Souza De Paula, B.; Spaan, B.; Spradlin, P.; Sridharan, S.; Stagni, F.; Stahl, M.; Stahl, S.; Steinkamp, O.; Stenyakin, O.; Sterpka, F.; Stevenson-Moore, P.; Stoica, S.; Stone, S.; Storaci, B.; Stracka, S.; Straticiuc, M.; Straumann, U.; Stroili, R.; Sun, L.; Sutcliffe, W.; Swientek, K.; Swientek, S.; Syropoulos, V.; Szczekowski, M.; Szczypka, P.; Szumlak, T.; T'Jampens, S.; Tekampe, T.; Teklishyn, M.; Tellarini, G.; Teubert, F.; Thomas, C.; Thomas, E.; van Tilburg, J.; Tisserand, V.; Tobin, M. N.; Todd, Jim; Tolk, S.; Tomassetti, L.; Tonelli, D.; Topp-Joergensen, S.; Torr, N.; Tournefier, E.; Tourneur, S.; Trabelsi, K.; Tran, N.T.M.T.; Tresch, M.; Trisovic, A.; Tsaregorodtsev, A.; Tsopelas, P.; Tuning, N.; Garcia, M. Ubeda; Ukleja, A.; Ustyuzhanin, A.; Uwer, U.; Vacca, C.; Vagnoni, V.; Valenti, G.; Vallier, A.; Gomez, R. Vazquez; Vazquez Regueiro, P.; Vazquez Sierra, C.; Vecchi, S.; Velthuis, M.J.; Veltri, M.; Veneziano, G.; Vesterinen, M.; Viaud, B.; Vieira, D.; Vieites Diaz, M.; Vilasis-Cardona, X.; Vollhardt, A.; Volyanskyy, D.; Voong, D.; Vorobyev, A.; Vorobyev, V.; Voss, C.; de Vries, J. A.; Waldi, R.; Wallace, C.; Wallace, R.; Walsh, John; Wandernoth, S.; Wang, J.; Ward, D. R.; Watson, N. K.; Websdale, D.; Weiden, A.; Whitehead, M.; Wiedner, D.; Wilkinson, G.; Wilkinson, M.; Williams, M.; Williams, M.P.; Williams, M.; Wilson, James F; Wimberley, J.; Wishahi, J.; Wislicki, W.; Witek, M.; Wormser, G.; Wotton, S. A.; Wright, S.J.; Wyllie, K.; Xie, Y.; Xu, Z.; Yang, Z.; Yuan, X.; Yushchenko, O.; Zangoli, M.; Zavertyaev, M.; Zhang, L.; Zhang, Y.; Zhelezov, A.; Zhokhov, A.; Zhong, L.

    2015-01-01

    A search is performed for heavy long-lived charged particles using 3.0 fb(-1) of proton-proton collisions collected at √s = 7 and 8 TeV with the LHCb detector. The search is mainly based on the response of the ring imaging Cherenkov detectors to distinguish the heavy, slow-moving particles from

  3. Mini-jet production in proton-antiproton interactions and particle production in heavy-ion collisions

    International Nuclear Information System (INIS)

    Wang Haiqiao.

    1997-04-01

    The thesis is based on the data analysis and detector development of the EMU01/CERN, E863/BNL and UA1/CERN experiments. Particle fluctuations are studied with the scaled factorial moments in the fragmentation region of oxygen induced emulsion interactions from 3.7 to 200 A GeV. The intermittency indices show an energy independent behaviour in the target and projectile regions of pseudorapidity. In order to study the origin of the fluctuations, jet-like and ring-like substructures of particles produced in the azimuthal plane are investigated for the S - Au, S - Em and O - Em interactions at 200 A GeV. The study shows that the two particle azimuthal correlations can be well understood if Bose-Einstein correlations and γ-conversion are included. A nuclear rescattering model, which incorporates the FRITIOF model, has been developed. The model can well describe multiplicity distributions of slow recoiling protons, evaporation particles and their correlations with particles produced in high energy heavy ion collisions. In order to improve the measurements of Pb induced collisions, an automatic system based on the CCD technique and image processing was developed. This system has been used to measure densities of the particles produced. Mini-jet production is studied using the UA1 1987 minimum bias data sample for p (anti) interaction at s 1/2 0 630 GeV. The study shows that the transverse energy distribution of mini-jets is in good agreement with the QCD prediction. The angular distributions of two leading jets show the behaviour of elastic scattering of partons with gluon exchange. 86 refs

  4. Gauge hierarchy, decoupling, and heavy particle effects

    International Nuclear Information System (INIS)

    Yao, York-Peng

    1981-01-01

    This chapter examines the problems of a large gauge hierarchy and decoupling in theories with spontaneously broken symmetry. Attempts to show, with regard to all orders in the loop expansion, that: once a proper identification is made of the light particles and of the heavy particles at the tree level, then such a division will be maintained order by order in the loop expansion without the necessity of fine tuning; there is a local renormalizable effective Lagrangian, composed of light fields only, which can be used to reproduce all the one light particle irreducible Green's functions; and a set of renormalization group equations can be written down, wherein one stays in the lower energy region to correlate the two sets of parameters in the full and the effective light theories. The appendix gives an algebraic rearrangement method which can be efficiently used to calculate the muon effects on the electron anomalous magnetic moment

  5. Heavy-ion radiation induced bystander effect in mice

    Science.gov (United States)

    Liang, Shujian; Sun, Yeqing; Zhang, Meng; Wang, Wei; Cui, Changna

    2012-07-01

    Radiation-induced bystander effect is defined as the induction of damage in neighboring non-hit cells by signals released from directly-irradiated cells. Recently, Low dose of high LET radiation induced bystander effects in vivo have been reported more and more. It has been indicated that radiation induced bystander effect was localized not only in bystander tissues but also in distant organs. Genomic, epigenetic, metabolomics and proteomics play significant roles in regulating heavy-ion radiation stress responses in mice. To identify the molecular mechanism that underlies bystander effects of heavy-ion radiation, the male mice head were exposed to 2000mGy dose of 12C heavy-ion radiation and the distant organ liver was detected on 1h, 6h, 12h and 24h after radiation, respectively. MSAP was used to monitor the level of polymorphic DNA methylation changes. The results show that heavy-ion irradiate mouse head can induce liver DNA methylation changes significantly. The percent of DNA methylation changes are time-dependent and highest at 6h after radiation. We also prove that the hypo-methylation changes on 1h and 6h after irradiation. But the expression level of DNA methyltransferase DNMT3a is not changed. UPLC/Synapt HDMS G2 was employed to detect the proteomics of bystander liver 1h after irradiation. 64 proteins are found significantly different between treatment and control group. GO process show that six of 64 which were unique in irradiation group are associated with apoptosis and DNA damage response. The results suggest that mice head exposed to heavy-ion radiation can induce damage and methylation pattern changed in distant organ liver. Moreover, our findings are important to understand the molecular mechanism of radiation induced bystander effects in vivo.

  6. Searches for long-lived heavy particles, HSCP, monopoles (ATLAS+CMS)

    CERN Document Server

    Lenz, Teresa

    2016-01-01

    Long-lived particles are contained in a variety of beyond Standard Model theories, including supersymmetric models, universal extra dimensions, or technicolor theories. If the lifetime of such a particle is long enough, the particle can enter - or even pass through - the detector before it decays. Therefore, searches for long-lived particles require a very different search strategy compared to conventional searches for particles beyond the Standard Model.If the new particle is not only weakly interacting, the particle can be reconstructed itself and not only via its decay products.A very specific characteristic of such new heavy charged particles is their large ionization losses when traveling through the detector.This article summarizes searches for long-lived particles at the CMS and ATLAS experiments that exploit the potentially high ionization losses per path length ($dE/dx$) of the new particle.The presented searches are performed on 8 and/or 13\\,TeV data. Additionally, an overview of the methodology of ...

  7. Nuclear fission induced by heavy ions

    International Nuclear Information System (INIS)

    Newton, J.O.

    1988-09-01

    Because the accelerators of the 50's and 60's mostly provided beams of light ions, well suited for studying individual quantum states of low angular momentum or reactions involving the transfer of one or two nucleons, the study of fission, being an example of large-scale collective motion, has until recently been outside of the mainstream of nuclear research. This situation has changed in recent years, due to the new generation of accelerators capable of producing beams of heavy ions with energies high enough to overcome the Coulomb barriers of all stable nuclei. These have made possible the study of new examples of large-scale collective motions, involving major rearrangements of nuclear matter, such as deep-inelastic collisions and heavy-ion fusion. Perhaps the most exciting development in the past few years is the discovery that dissipative effects (nuclear viscosity) play an important role in fission induced by heavy ions, contrary to earlier assumptions that the viscosity involved in fission was very weak and played only a minor role. This review will be mainly concerned with developments in heavy-ion induced fission during the last few years and have an emphasis on the very recent results on dissipative effects. Since heavy-ion bombardment usually results in compound systems with high excitation energies and angular momenta, shell effects might be expected to be small, and the subject of low energy fission, where they are important, will not be addressed. 285 refs., 58 figs

  8. Universal behavior of charged particle production in heavy ion collisions at RHIC energies

    Science.gov (United States)

    Steinberg, Peter A.; Back, B. B.; Baker, M. D.; Barton, D. S.; Betts, R. R.; Ballintijn, M.; Bickley, A. A.; Bindel, R.; Budzanowski, A.; Busza, W.; Carroll, A.; Decowski, M. P.; García, E.; George, N.; Gulbrandsen, K.; Gushue, S.; Halliwell, C.; Hamblen, J.; Heintzelman, G. A.; Henderson, C.; Hofman, D. J.; Hollis, R. S.; Holyński, R.; Holzman, B.; Iordanova, A.; Johnson, E.; Kane, J. L.; Katzy, J.; Khan, N.; Kucewicz, W.; Kulinich, P.; Kuo, C. M.; Lin, W. T.; Manly, S.; McLeod, D.; Michałowski, J.; Mignerey, A. C.; Nouicer, R.; Olszewski, A.; Pak, R.; Park, I. C.; Pernegger, H.; Reed, C.; Remsberg, L. P.; Reuter, M.; Roland, C.; Roland, G.; Rosenberg, L.; Sagerer, J.; Sarin, P.; Sawicki, P.; Skulski, W.; Steadman, S. G.; Steinberg, P.; Stephans, G. S. F.; Stodulski, M.; Sukhanov, A.; Tang, J.-L.; Teng, R.; Trzupek, A.; Vale, C.; van Nieuwenhuizen, G. J.; Verdier, R.; Wadsworth, B.; Wolfs, F. L. H.; Wosiek, B.; Woźniak, K.; Wuosmaa, A. H.; Wysłouch, B.; Phobos Collaboration

    2003-04-01

    The PHOBOS experiment at RHIC has measured the multiplicity of primary charged particles as a function of centrality and pseudorapidity in Au+Au collisions at √ SNN = 19.6, 130 and 200 GeV. Two kinds of universal behavior are observed in charged particle production in heavy ion collisions. The first is that forward particle production, over a range of energies, follows a universal limiting curve with a non-trivial centrality dependence. The second arises from comparisons with pp/ overlinepp and e +e - data. / in nuclear collisions at high energy scales with √ s in a similar way as Nch in e +e - collisions and has a very weak centrality dependence. This feature may be related to a reduction in the leading particle effect due to the multiple collisions suffered per participant in heavy ion collisions.

  9. PHITS: Particle and heavy ion transport code system, version 2.23

    International Nuclear Information System (INIS)

    Niita, Koji; Matsuda, Norihiro; Iwamoto, Yosuke; Sato, Tatsuhiko; Nakashima, Hiroshi; Sakamoto, Yukio; Iwase, Hiroshi; Sihver, Lembit

    2010-10-01

    A Particle and Heavy-Ion Transport code System PHITS has been developed under the collaboration of JAEA (Japan Atomic Energy Agency), RIST (Research Organization for Information Science and Technology) and KEK (High Energy Accelerator Research Organization). PHITS can deal with the transport of all particles (nucleons, nuclei, mesons, photons, and electrons) over wide energy ranges, using several nuclear reaction models and nuclear data libraries. Geometrical configuration of the simulation can be set with GG (General Geometry) or CG (Combinatorial Geometry). Various quantities such as heat deposition, track length and production yields can be deduced from the simulation, using implemented estimator functions called 'tally'. The code also has a function to draw 2D and 3D figures of the calculated results as well as the setup geometries, using a code ANGEL. Because of these features, PHITS has been widely used for various purposes such as designs of accelerator shielding, radiation therapy and space exploration. Recently PHITS introduces an event generator for particle transport parts in the low energy region. Thus, PHITS was completely rewritten for the introduction of the event generator for neutron-induced reactions in energy region less than 20 MeV. Furthermore, several new tallis were incorporated for estimation of the relative biological effects. This document provides a manual of the new PHITS. (author)

  10. Cell killing and chromosomal aberration induced by heavy-ion beams in cultured human tumor cells

    International Nuclear Information System (INIS)

    Takakura, K.; Funada, A.; Mohri, M.; Lee, R.; Aoki, M.; Furusawa, Y.; Gotoh, E.

    2003-01-01

    Full text: To clarify the relation between cell death and chromosomal aberration in cultured human tumor cells irradaited with heavy-ion beams. The analyses were carried out on the basis of the linear energy transfer (LET) values of heavy ion beams as radiation source. Exponentially growing human tumor cells, Human Salivary Gland Tumor cells (HSG cells), were irradiated with various high energy heavy ions, such as 13 keV/micrometer carbon (C) ions as low LET charged particle radiation source, 120 keV/ micrometer carbon (C) ions and 440 keV/micrometer iron (Fe) ions as high LET charged particle radiation sources.The cell death was analysed by the colony formation method, and the chromosomal aberration and its repairing kinetics was analysed by prematurely chromosome condensation method (PCC method) using calyculin A. Chromatid-type breaks, isochromatid breaks and exchanges were scored for the samples from the cells keeping with various incubation time after irradiation. The LET dependence of the cell death was similar to that of the chromosome exchange formation after 12 hours incubation. A maximum peak was around 120 keV/micrometer. However it was not similar to the LET dependence of isochromatid breaks or chromatid breaks after 12 hours incubation. These results suggest that the exchanges formed in chromosome after irradiation should be one of essential causes to lead the cell death. The different quality of induced chromosome damage between high-LET and low-LET radiation was also shown. About 89 % and 88 % chromatid breaks induced by X rays and 13 keV/micrometer C ions were rejoined within 12 hours of post-irradiation, though only 71% and 58 % of chromatid breaks induced by 120 keV/micrometer C ions and 440 keV/micrometer Fe ions were rejoined within 12 hours of post-irradiation

  11. Energy distribution of projectile fragment particles in heavy ion therapeutic beam

    Energy Technology Data Exchange (ETDEWEB)

    Matsufuji, Naruhiro; Tomura, Hiromi; Futami, Yasuyuki [National Inst. of Radiological Sciences, Chiba (Japan)] [and others

    1998-03-01

    Production of fragment particles in a patient`s body is one of important problems for heavy charged particle therapy. It is required to know the yield and the energy spectrum for each fragment element - so called `beam quality` to understand the effect of therapeutic beam precisely. In this study, fragment particles produced by practical therapeutic beam of HIMAC were investigated with using tissue-equivalent material and a detector complex. From the results, fragment particles were well identified by difference of their atomic numbers and the beam quality was derived. Responses of the detectors in this energy region were also researched. (author)

  12. [Aerodynamic focusing of particles and heavy molecules

    International Nuclear Information System (INIS)

    de la Mora, J.F.

    1990-01-01

    By accelerating a gas containing suspended particles or large molecules through a converging nozzle, the suspended species may be focused and therefore used to write fine lines on a surface. Our objective was to study the limits on how narrow this focal region could be as a function of particle size. We find that, for monodisperse particles with masses m p some 3.6 x 10 5 times larger than the molecular mass m of the carrier gas (diameters above some 100 angstrom), there is no fundamental obstacle to directly write submicron features. However, this conclusion has been verified experimentally only with particles larger than 0.1 μm. Experimental, theoretical and numerical studies on the defocusing role of Brownian motion for very small particles or heavy molecules have shown that high resolution (purely aerodynamic) focusing is impossible with volatile molecules whose masses are typically smaller than 1000 Dalton. For these, the minimal focal diameter after optimization appears to be 5√(m/m p ) times the nozzle diameter d n . But combinations of focused lasers and aerodynamic focusing appear as promising for direct writing with molecular precursors. Theoretical and numerical schemes capable of predicting the evolution of the focusing beam, including Brownian motion effects, have been developed, although further numerical work would be desirable. 11 refs

  13. Intermittency in the relative separations of tracers and of heavy particles in turbulent flows

    NARCIS (Netherlands)

    Biferale, L.; Lanotte, A.S.; Scatamacchia, R.; Toschi, F.

    2014-01-01

    Results from direct numerical simulations (DNS) of particle relative dispersion in three-dimensional homogeneous and isotropic turbulence at Reynolds number Re_¿ ~ 300 are presented. We study point-like passive tracers and heavy particles, at Stokes number St = 0.6, 1 and 5. Particles are emitted

  14. Population and particle decay of isobaric analog states in medium heavy nuclei

    International Nuclear Information System (INIS)

    Gales, S.

    1980-05-01

    The systematic features of proton stripping and neutron pick-up reactions to Isobaric Analog States in medium heavy nuclei are presented. The ( 3 He,d) reaction investigated at high incident energy is shown to selectively excite high-spin particle-analog states. Similarly the ( 3 He,α) reaction populates hole-analog states. The recent results related to such highly excited states in a wide range of nuclei ( 48 Ca to 208 Pb) are discussed in the framework of the DWBA theory of direct reactions with special emphasis on the treatment of unbound proton states or deeply-bound neutron hole states. The particle decay of Isobaric Analog States are investigated using the ( 3 He,d p) and ( 3 He, α p) sequential processes. The experimental method developed at Orsay (0 0 detection) for particle-particle angular correlations is presented. The advantage and the limits of such approach are illustrated by typical examples of particle decays: core-excited states, neutron particle-hole multiplets and the first observation of the proton emission of hole-analog levels. In conclusion new experimental approaches such as asymmetry measurements for analog states observed in transfer reactions or possible population of double analog states in heavy nuclei are discussed

  15. Heavy-ion induced current through an oxide layer

    International Nuclear Information System (INIS)

    Takahashi, Yoshihiro; Ohki, Takahiro; Nagasawa, Takaharu; Nakajima, Yasuhito; Kawanabe, Ryu; Ohnishi, Kazunori; Hirao, Toshio; Onoda, Shinobu; Mishima, Kenta; Kawano, Katsuyasu; Itoh, Hisayoshi

    2007-01-01

    In this paper, the heavy-ion induced current in MOS structure is investigated. We have measured the transient gate current in a MOS capacitor and a MOSFET induced by single heavy-ions, and found that a transient current can be observed when the semiconductor surface is under depletion condition. In the case of MOSFET, a transient gate current with both positive and negative peaks is observed if the ion hits the gate area, and that the total integrated charge is almost zero within 100-200 ns after irradiation. From these results, we conclude that the radiation-induced gate current is dominated by a displacement current. We also discuss the generation mechanism of the radiation-induced current through the oxide layer by device simulation

  16. Search for Heavy Long-Lived Particles in ATLAS

    CERN Document Server

    Kajomovitz, Enrique

    This thesis presents a search for long-lived particles through a measuremt of their mass performed on a data sample of \\lumi from proton-proton collisions at a centre-of-mass energy $\\sqrt{s} = 7~\\TeV$ collected by the ATLAS detector at the LHC in 2011. The mass of the long-lived particles is estimated from a measurement of their speed, $\\beta$, and their momentum measurements using the relation $m=p/\\beta\\gamma$. Two distinct types of LLPs are sought after; sleptons, the supersymmetric partners of the Standard Model leptons, and \\rhads, colorless bound states that include a colored supersymmetric long-lived particle in addition to colored Standard Model particles. Sleptons are expected to interact with the detector as if they were heavy muons, charged throughout the detector and penetrating. In contrast, \\rhads~may change charge in the detector due to the strong interactions between the light quarks in the \\rhads~with the detector material. Thus, \\rhads~may be charged in the ID and neutral in the MS or...

  17. Transversely Excited Atmospheric CO2 Laser-Induced Plasma Spectroscopy for the Detection of Heavy Metals in Soil

    Science.gov (United States)

    Khumaeni, A.; Sugito, H.; Setia Budi, W.; Yoyo Wardaya, A.

    2018-01-01

    A rapid detection of heavy metals in soil was presented by the metal-assisted gas plasma method using specific characteristics of a pulsed, transversely excited atmospheric (TEA) CO2 laser. The soil particles were placed in a hole made of acrylic plate. The sample was covered by a to prevent the soil particles from being blown off. The mesh also functioned to initiate a luminous plasma. When a TEA CO2 laser (1500 mJ, 200 ns) was focused on the soil sample, passing through the metal mesh, some of the laser energy was used to generate the gas plasma on the mesh surface, and the remaining laser energy was employed to ablate the soil particles. The fine, ablated soil particles moved into the gas plasma region to be dissociated and excited. Using this technique, analysis can be made with reduced sample pretreatment, and therefore a rapid analysis can be performed efficiently. The results proved that the signal to noise ratio (S/N) of the emission spectral lines is much better for the case of the present method (mesh method) compared to the case of standard laser-induced breakdown spectroscopy using the pellet method. Rapid detection of heavy metal elements in soil has been successfully carried out. The detection limits of Cu and Hg in soil were estimated to be 3 and 10 mg/kg, respectively. The present method has good potential for rapid and sensitive detection of heavy metals in soil samples.

  18. Heavy ion induced mutation in arabidopsis

    Energy Technology Data Exchange (ETDEWEB)

    Tano, Shigemitsu [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment

    1997-03-01

    Heavy ions, He, C, Ar and Ne were irradiated to the seeds of Arabidopsis thaliana for inducing the new mutants. In the irradiated generation (M{sub 1}), germination and survival rate were observed to estimate the relative biological effectiveness in relation to the LET including the inactivation cross section. Mutation frequencies were compared by using three kinds of genetic loci after irradiation with C ions and electrons. Several interesting new mutants were selected in the selfed progenies of heavy ion irradiated seeds. (author)

  19. The effects of heavy ion particles on the developing murine cerebellum, with special reference to cell death

    International Nuclear Information System (INIS)

    Kinoshita, Chikako; Yaoi, Takeshi; Fushiki, Shinji; Nojima, Kumie

    2003-01-01

    We report here the effects of heavy ion beams on postnatal mouse cerebellar development, with reference to cell death. Eight-day-old B6C3F1 mice were irradiated with single doses of 0.1, 0.25, 0.5, 1.0, and 2.0 Gy, using a carbon beam of 290 MeV delivered from a heavy ion medical accelerator in Chiba (HIMAC). To compare the effects of X-rays with those of accelerated carbon ions, 8-day-old mice were exposed to X-rays single doses of 0.1, 0.25, 0.5, 1.0, and 2.0 Gy, respectively. Pups were fixed at 1, 6, 12 and 24 hr after exposure to HIMAC beams or X-rays. Four-μm-thick parasagittal sections of the cerebella were processed for hematoxylin-eosin staining as well as for staining with the TUNEL (terminal dUTP nick-end labeling) technique. The density of fragmented nuclei in the external granular layer increased with time, peaking at 6 hr after exposure, in both the HIMAC and X-irradiated groups. In the HIMAC groups, the density was significantly higher in those animals exposed to 0.25 Gy or more compared to 0 Gy, whereas in the X-irradiated groups it was significantly higher in those mice exposed to 0.5 Gy or more. Electron microscopic examinations revealed chromatin condensation in the cell nuclei in the HIMAC groups. This is the first in vivo evidence that apoptotic cell death is induced in developing mouse cerebellum after exposure to heavy ion particles. The difference in the frequency of dying cells between exposure to heavy ion particles and to X-rays may reflect the high linear energy transfer (LET) associated with a heavy ion beam. (author)

  20. Quantum theory of nonadiabatic heavy-particle transfer processes in polar media

    International Nuclear Information System (INIS)

    Kuznetsov, A.M.

    1986-01-01

    For the probability of nonadiabatic transfer of heavy particles, a calculating procedure is proposed which in the case of certain processes allows the interaction between motion of the particle undergoing transfer and motion along other degrees of freedom to be exactly accounted for. In the case of symmetric systems, explicit expressions are obtained for the free energy of activation of the transition and for the tunneling factor which allow for nonadiabaticity of motion of the particle undergoing transfer, both in the region beneath the barrier and in the region that is classically accessible

  1. Elaboration by ion implantation of cobalt nano-particles in silica layers and modifications of their properties by electron and swift heavy ion irradiations

    International Nuclear Information System (INIS)

    D'Orleans, C.

    2003-07-01

    This work aims to investigate the capability of ion irradiations to elaborate magnetic nano-particles in silica layers, and to modify their properties. Co + ions have been implanted at 160 keV at fluences of 2.10 16 , 5.10 16 and 10 17 at/cm 2 , and at temperatures of 77, 295 and 873 K. The dependence of the particle size on the implantation fluence, and more significantly on the implantation temperature has been shown. TEM (transmission electronic microscopy) observations have shown a mean diameter varying from 1 nm for implantations at 2.10 16 Co + /cm 2 at 77 K, to 9.7 nm at 10 17 Co + /cm 2 at 873 K. For high temperature implantations, two regions of particles appear. Simulations based on a kinetic 3-dimensional lattice Monte Carlo method reproduce quantitatively the features observed for implantations. Thermal treatments induce the ripening of the particles. Electron irradiations at 873 K induce an important increase in mean particle sizes. Swift heavy ion irradiations also induce the ripening of the particles for low fluences, and an elongation of the particles in the incident beam direction for high fluences, resulting in a magnetic anisotropy. Mechanisms invoked in thermal spike model could also explain this anisotropic growth. (author)

  2. Semiclassical approach to trajectory effects on the anisotropy coefficient of L3-subshell X-rays induced by slow heavy particles collisions

    International Nuclear Information System (INIS)

    Montenegro, E.C.; Pinho, A.G. de

    1982-01-01

    The deflection and the retardation of a slow bare heavy particle by the repulsive Coulomb field of the target nucleus are known to modify the ionization cross sections of inner shells. It is shown how to calculate these effects in the magnetic substates of the 2p-subshell in the frame of the impact parameter picture. These corrections are essential to understand the energy dependence of the anisotropy coefficient of X-ray emitted in transitions filling an L 3 -subshell vacancy produced by massive particle bombardment. (Author) [pt

  3. Particle Production in Strong Electromagnetic Fields in Relativistic Heavy-Ion Collisions

    Directory of Open Access Journals (Sweden)

    Kirill Tuchin

    2013-01-01

    Full Text Available I review the origin and properties of electromagnetic fields produced in heavy-ion collisions. The field strength immediately after a collision is proportional to the collision energy and reaches ~mπ2 at RHIC and ~10mπ2 at LHC. I demonstrate by explicit analytical calculation that after dropping by about one-two orders of magnitude during the first fm/c of plasma expansion, it freezes out and lasts for as long as quark-gluon plasma lives as a consequence of finite electrical conductivity of the plasma. Magnetic field breaks spherical symmetry in the direction perpendicular to the reaction plane, and therefore all kinetic coefficients are anisotropic. I examine viscosity of QGP and show that magnetic field induces azimuthal anisotropy on plasma flow even in spherically symmetric geometry. Very strong electromagnetic field has an important impact on particle production. I discuss the problem of energy loss and polarization of fast fermions due to synchrotron radiation, consider photon decay induced by magnetic field, elucidate J/ψ dissociation via Lorentz ionization mechanism, and examine electromagnetic radiation by plasma. I conclude that all processes in QGP are affected by strong electromagnetic field and call for experimental investigation.

  4. Heavy particle effects

    International Nuclear Information System (INIS)

    Yao, Y.P.

    1981-01-01

    There are two problems discussed, both of which have to do with dissimilar magnitudes in mass. Theoretically, we can devise the large difference in mass as observed by decreeing some vev, v/sub i/ to be much bigger than the other; or, we can assume that some couplings g/sub i/ are much stronger. These two different assumptions give rise to entirely different patterns of interaction in the resulting theory. The first way to generate a mass hierarchy can be called the soft way, because in the zeroth order, the large mass scale leaves its foot print merely in a few effective parameters of the residual theory. The effective theory is renormalizable, sans anomaly. In this limit, the heavy particles decouple. The second assumption (g/sub j/ much greater than g/sub j'/) to create mass hierarchy does a lot of violence to a theory. Effects of the large mass scale will be felt by the system left behind in many ways. An infinite number of parameters are needed to summarize the effects in this limit. This is called the hard limit. It follows that the resulting effective Lagrangian, if in fact it makes sense to construct one at all, will be non-polynomial and apparently non-renormalizable

  5. Search for heavy neutral leptons, right-handed neutrinos and long-lived particles with the CMS detector

    CERN Document Server

    Negro, Giulia

    2018-01-01

    A selection of recent CMS results on heavy neutral leptons, right-handed neutrinos and long-lived particles is reported. The search for heavy neutral leptons in the trilepton channel and in the same-sign dilepton channel, the search of a $W_R$ decaying into two leptons and two jets through a right-handed neutrino, and the searches on stopped long-lived particles and disappearing tracks are presented.

  6. Search for long-lived heavy charged particles using a ring imaging Cherenkov technique at LHCb

    CERN Document Server

    Aaij, Roel; Adinolfi, Marco; Affolder, Anthony; Ajaltouni, Ziad; Akar, Simon; Albrecht, Johannes; Alessio, Federico; Alexander, Michael; Ali, Suvayu; Alkhazov, Georgy; Alvarez Cartelle, Paula; Alves Jr, Antonio Augusto; Amato, Sandra; Amerio, Silvia; Amhis, Yasmine; An, Liupan; Anderlini, Lucio; Anderson, Jonathan; Andreotti, Mirco; Andrews, Jason; Appleby, Robert; Aquines Gutierrez, Osvaldo; Archilli, Flavio; d'Argent, Philippe; Artamonov, Alexander; Artuso, Marina; Aslanides, Elie; Auriemma, Giulio; Baalouch, Marouen; Bachmann, Sebastian; Back, John; Badalov, Alexey; Baesso, Clarissa; Baldini, Wander; Barlow, Roger; Barschel, Colin; Barsuk, Sergey; Barter, William; Batozskaya, Varvara; Battista, Vincenzo; Bay, Aurelio; Beaucourt, Leo; Beddow, John; Bedeschi, Franco; Bediaga, Ignacio; Bel, Lennaert; Belyaev, Ivan; Ben-Haim, Eli; Bencivenni, Giovanni; Benson, Sean; Benton, Jack; Berezhnoy, Alexander; Bernet, Roland; Bertolin, Alessandro; Bettler, Marc-Olivier; van Beuzekom, Martinus; Bien, Alexander; Bifani, Simone; Bird, Thomas; Birnkraut, Alex; Bizzeti, Andrea; Blake, Thomas; Blanc, Frédéric; Blouw, Johan; Blusk, Steven; Bocci, Valerio; Bondar, Alexander; Bondar, Nikolay; Bonivento, Walter; Borghi, Silvia; Borgia, Alessandra; Borsato, Martino; Bowcock, Themistocles; Bowen, Espen Eie; Bozzi, Concezio; Brett, David; Britsch, Markward; Britton, Thomas; Brodzicka, Jolanta; Brook, Nicholas; Bursche, Albert; Buytaert, Jan; Cadeddu, Sandro; Calabrese, Roberto; Calvi, Marta; Calvo Gomez, Miriam; Campana, Pierluigi; Campora Perez, Daniel; Capriotti, Lorenzo; Carbone, Angelo; Carboni, Giovanni; Cardinale, Roberta; Cardini, Alessandro; Carniti, Paolo; Carson, Laurence; Carvalho Akiba, Kazuyoshi; Casanova Mohr, Raimon; Casse, Gianluigi; Cassina, Lorenzo; Castillo Garcia, Lucia; Cattaneo, Marco; Cauet, Christophe; Cavallero, Giovanni; Cenci, Riccardo; Charles, Matthew; Charpentier, Philippe; Chefdeville, Maximilien; Chen, Shanzhen; Cheung, Shu-Faye; Chiapolini, Nicola; Chrzaszcz, Marcin; Cid Vidal, Xabier; Ciezarek, Gregory; Clarke, Peter; Clemencic, Marco; Cliff, Harry; Closier, Joel; Coco, Victor; Cogan, Julien; Cogneras, Eric; Cogoni, Violetta; Cojocariu, Lucian; Collazuol, Gianmaria; Collins, Paula; Comerma-Montells, Albert; Contu, Andrea; Cook, Andrew; Coombes, Matthew; Coquereau, Samuel; Corti, Gloria; Corvo, Marco; Counts, Ian; Couturier, Benjamin; Cowan, Greig; Craik, Daniel Charles; Crocombe, Andrew; Cruz Torres, Melissa Maria; Cunliffe, Samuel; Currie, Robert; D'Ambrosio, Carmelo; Dalseno, Jeremy; David, Pieter; Davis, Adam; De Bruyn, Kristof; De Capua, Stefano; De Cian, Michel; De Miranda, Jussara; De Paula, Leandro; De Silva, Weeraddana; De Simone, Patrizia; Dean, Cameron Thomas; Decamp, Daniel; Deckenhoff, Mirko; Del Buono, Luigi; Déléage, Nicolas; Derkach, Denis; Deschamps, Olivier; Dettori, Francesco; Dey, Biplab; Di Canto, Angelo; Di Ruscio, Francesco; Dijkstra, Hans; Donleavy, Stephanie; Dordei, Francesca; Dorigo, Mirco; Dosil Suárez, Alvaro; Dossett, David; Dovbnya, Anatoliy; Dreimanis, Karlis; Dujany, Giulio; Dupertuis, Frederic; Durante, Paolo; Dzhelyadin, Rustem; Dziurda, Agnieszka; Dzyuba, Alexey; Easo, Sajan; Egede, Ulrik; Egorychev, Victor; Eidelman, Semen; Eisenhardt, Stephan; Eitschberger, Ulrich; Ekelhof, Robert; Eklund, Lars; El Rifai, Ibrahim; Elsasser, Christian; Ely, Scott; Esen, Sevda; Evans, Hannah Mary; Evans, Timothy; Falabella, Antonio; Färber, Christian; Farinelli, Chiara; Farley, Nathanael; Farry, Stephen; Fay, Robert; Ferguson, Dianne; Fernandez Albor, Victor; Ferrari, Fabio; Ferreira Rodrigues, Fernando; Ferro-Luzzi, Massimiliano; Filippov, Sergey; Fiore, Marco; Fiorini, Massimiliano; Firlej, Miroslaw; Fitzpatrick, Conor; Fiutowski, Tomasz; Fol, Philip; Fontana, Marianna; Fontanelli, Flavio; Forty, Roger; Francisco, Oscar; Frank, Markus; Frei, Christoph; Frosini, Maddalena; Fu, Jinlin; Furfaro, Emiliano; Gallas Torreira, Abraham; Galli, Domenico; Gallorini, Stefano; Gambetta, Silvia; Gandelman, Miriam; Gandini, Paolo; Gao, Yuanning; García Pardiñas, Julián; Garofoli, Justin; Garra Tico, Jordi; Garrido, Lluis; Gascon, David; Gaspar, Clara; Gauld, Rhorry; Gavardi, Laura; Gazzoni, Giulio; Geraci, Angelo; Gerick, David; Gersabeck, Evelina; Gersabeck, Marco; Gershon, Timothy; Ghez, Philippe; Gianelle, Alessio; Gianì, Sebastiana; Gibson, Valerie; Giubega, Lavinia-Helena; Gligorov, V.V.; Göbel, Carla; Golubkov, Dmitry; Golutvin, Andrey; Gomes, Alvaro; Gotti, Claudio; Grabalosa Gándara, Marc; Graciani Diaz, Ricardo; Granado Cardoso, Luis Alberto; Graugés, Eugeni; Graverini, Elena; Graziani, Giacomo; Grecu, Alexandru; Greening, Edward; Gregson, Sam; Griffith, Peter; Grillo, Lucia; Grünberg, Oliver; Gui, Bin; Gushchin, Evgeny; Guz, Yury; Gys, Thierry; Hadjivasiliou, Christos; Haefeli, Guido; Haen, Christophe; Haines, Susan; Hall, Samuel; Hamilton, Brian; Hampson, Thomas; Han, Xiaoxue; Hansmann-Menzemer, Stephanie; Harnew, Neville; Harnew, Samuel; Harrison, Jonathan; He, Jibo; Head, Timothy; Heijne, Veerle; Hennessy, Karol; Henrard, Pierre; Henry, Louis; Hernando Morata, Jose Angel; van Herwijnen, Eric; Heß, Miriam; Hicheur, Adlène; Hill, Donal; Hoballah, Mostafa; Hombach, Christoph; Hulsbergen, Wouter; Humair, Thibaud; Hussain, Nazim; Hutchcroft, David; Hynds, Daniel; Idzik, Marek; Ilten, Philip; Jacobsson, Richard; Jaeger, Andreas; Jalocha, Pawel; Jans, Eddy; Jawahery, Abolhassan; Jing, Fanfan; John, Malcolm; Johnson, Daniel; Jones, Christopher; Joram, Christian; Jost, Beat; Jurik, Nathan; Kandybei, Sergii; Kanso, Walaa; Karacson, Matthias; Karbach, Moritz; Karodia, Sarah; Kelsey, Matthew; Kenyon, Ian; Kenzie, Matthew; Ketel, Tjeerd; Khanji, Basem; Khurewathanakul, Chitsanu; Klaver, Suzanne; Klimaszewski, Konrad; Kochebina, Olga; Kolpin, Michael; Komarov, Ilya; Koopman, Rose; Koppenburg, Patrick; Kravchuk, Leonid; Kreplin, Katharina; Kreps, Michal; Krocker, Georg; Krokovny, Pavel; Kruse, Florian; Kucewicz, Wojciech; Kucharczyk, Marcin; Kudryavtsev, Vasily; Kurek, Krzysztof; Kvaratskheliya, Tengiz; La Thi, Viet Nga; Lacarrere, Daniel; Lafferty, George; Lai, Adriano; Lambert, Dean; Lambert, Robert W; Lanfranchi, Gaia; Langenbruch, Christoph; Langhans, Benedikt; Latham, Thomas; Lazzeroni, Cristina; Le Gac, Renaud; van Leerdam, Jeroen; Lees, Jean-Pierre; Lefèvre, Regis; Leflat, Alexander; Lefrançois, Jacques; Leroy, Olivier; Lesiak, Tadeusz; Leverington, Blake; Li, Yiming; Likhomanenko, Tatiana; Liles, Myfanwy; Lindner, Rolf; Linn, Christian; Lionetto, Federica; Liu, Bo; Lohn, Stefan; Longstaff, Iain; Lopes, Jose; Lucchesi, Donatella; Luo, Haofei; Lupato, Anna; Luppi, Eleonora; Lupton, Oliver; Machefert, Frederic; Machikhiliyan, Irina V; Maciuc, Florin; Maev, Oleg; Malde, Sneha; Malinin, Alexander; Manca, Giulia; Mancinelli, Giampiero; Manning, Peter Michael; Mapelli, Alessandro; Maratas, Jan; Marchand, Jean François; Marconi, Umberto; Marin Benito, Carla; Marino, Pietro; Märki, Raphael; Marks, Jörg; Martellotti, Giuseppe; Martinelli, Maurizio; Martinez Santos, Diego; Martinez Vidal, Fernando; Martins Tostes, Danielle; Massafferri, André; Matev, Rosen; Mathe, Zoltan; Matteuzzi, Clara; Mauri, Andrea; Maurin, Brice; Mazurov, Alexander; McCann, Michael; McCarthy, James; McNab, Andrew; McNulty, Ronan; McSkelly, Ben; Meadows, Brian; Meier, Frank; Meissner, Marco; Merk, Marcel; Milanes, Diego Alejandro; Minard, Marie-Noelle; Mitzel, Dominik Stefan; Molina Rodriguez, Josue; Monteil, Stephane; Morandin, Mauro; Morawski, Piotr; Mordà, Alessandro; Morello, Michael Joseph; Moron, Jakub; Morris, Adam Benjamin; Mountain, Raymond; Muheim, Franz; Müller, Janine; Müller, Katharina; Müller, Vanessa; Mussini, Manuel; Muster, Bastien; Naik, Paras; Nakada, Tatsuya; Nandakumar, Raja; Nasteva, Irina; Needham, Matthew; Neri, Nicola; Neubert, Sebastian; Neufeld, Niko; Neuner, Max; Nguyen, Anh Duc; Nguyen, Thi-Dung; Nguyen-Mau, Chung; Niess, Valentin; Niet, Ramon; Nikitin, Nikolay; Nikodem, Thomas; Novoselov, Alexey; O'Hanlon, Daniel Patrick; Oblakowska-Mucha, Agnieszka; Obraztsov, Vladimir; Ogilvy, Stephen; Okhrimenko, Oleksandr; Oldeman, Rudolf; Onderwater, Gerco; Osorio Rodrigues, Bruno; Otalora Goicochea, Juan Martin; Otto, Adam; Owen, Patrick; Oyanguren, Maria Aranzazu; Palano, Antimo; Palombo, Fernando; Palutan, Matteo; Panman, Jacob; Papanestis, Antonios; Pappagallo, Marco; Pappalardo, Luciano; Parkes, Christopher; Passaleva, Giovanni; Patel, Girish; Patel, Mitesh; Patrignani, Claudia; Pearce, Alex; Pellegrino, Antonio; Penso, Gianni; Pepe Altarelli, Monica; Perazzini, Stefano; Perret, Pascal; Pescatore, Luca; Petridis, Konstantinos; Petrolini, Alessandro; Picatoste Olloqui, Eduardo; Pietrzyk, Boleslaw; Pilař, Tomas; Pinci, Davide; Pistone, Alessandro; Playfer, Stephen; Plo Casasus, Maximo; Poikela, Tuomas; Polci, Francesco; Poluektov, Anton; Polyakov, Ivan; Polycarpo, Erica; Popov, Alexander; Popov, Dmitry; Popovici, Bogdan; Potterat, Cédric; Price, Eugenia; Price, Joseph David; Prisciandaro, Jessica; Pritchard, Adrian; Prouve, Claire; Pugatch, Valery; Puig Navarro, Albert; Punzi, Giovanni; Qian, Wenbin; Quagliani, Renato; Rachwal, Bartolomiej; Rademacker, Jonas; Rakotomiaramanana, Barinjaka; Rama, Matteo; Rangel, Murilo; Raniuk, Iurii; Rauschmayr, Nathalie; Raven, Gerhard; Redi, Federico; Reichert, Stefanie; Reid, Matthew; dos Reis, Alberto; Ricciardi, Stefania; Richards, Sophie; Rihl, Mariana; Rinnert, Kurt; Rives Molina, Vincente; Robbe, Patrick; Rodrigues, Ana Barbara; Rodrigues, Eduardo; Rodriguez Perez, Pablo; Roiser, Stefan; Romanovsky, Vladimir; Romero Vidal, Antonio; Rotondo, Marcello; Rouvinet, Julien; Ruf, Thomas; Ruiz, Hugo; Ruiz Valls, Pablo; Saborido Silva, Juan Jose; Sagidova, Naylya; Sail, Paul; Saitta, Biagio; Salustino Guimaraes, Valdir; Sanchez Mayordomo, Carlos; Sanmartin Sedes, Brais; Santacesaria, Roberta; Santamarina Rios, Cibran; Santovetti, Emanuele; Sarti, Alessio; Satriano, Celestina; Satta, Alessia; Saunders, Daniel Martin; Savrina, Darya; Schiller, Manuel; Schindler, Heinrich; Schlupp, Maximilian; Schmelling, Michael; Schmelzer, Timon; Schmidt, Burkhard; Schneider, Olivier; Schopper, Andreas; Schune, Marie Helene; Schwemmer, Rainer; Sciascia, Barbara; Sciubba, Adalberto; Semennikov, Alexander; Sepp, Indrek; Serra, Nicola; Serrano, Justine; Sestini, Lorenzo; Seyfert, Paul; Shapkin, Mikhail; Shapoval, Illya; Shcheglov, Yury; Shears, Tara; Shekhtman, Lev; Shevchenko, Vladimir; Shires, Alexander; Silva Coutinho, Rafael; Simi, Gabriele; Sirendi, Marek; Skidmore, Nicola; Skillicorn, Ian; Skwarnicki, Tomasz; Smith, Edmund; Smith, Eluned; Smith, Jackson; Smith, Mark; Snoek, Hella; Sokoloff, Michael; Soler, Paul; Soomro, Fatima; Souza, Daniel; Souza De Paula, Bruno; Spaan, Bernhard; Spradlin, Patrick; Sridharan, Srikanth; Stagni, Federico; Stahl, Marian; Stahl, Sascha; Steinkamp, Olaf; Stenyakin, Oleg; Sterpka, Christopher Francis; Stevenson, Scott; Stoica, Sabin; Stone, Sheldon; Storaci, Barbara; Stracka, Simone; Straticiuc, Mihai; Straumann, Ulrich; Stroili, Roberto; Sun, Liang; Sutcliffe, William; Swientek, Krzysztof; Swientek, Stefan; Syropoulos, Vasileios; Szczekowski, Marek; Szczypka, Paul; Szumlak, Tomasz; T'Jampens, Stephane; Tekampe, Tobias; Teklishyn, Maksym; Tellarini, Giulia; Teubert, Frederic; Thomas, Christopher; Thomas, Eric; van Tilburg, Jeroen; Tisserand, Vincent; Tobin, Mark; Todd, Jacob; Tolk, Siim; Tomassetti, Luca; Tonelli, Diego; Topp-Joergensen, Stig; Torr, Nicholas; Tournefier, Edwige; Tourneur, Stephane; Trabelsi, Karim; Tran, Minh Tâm; Tresch, Marco; Trisovic, Ana; Tsaregorodtsev, Andrei; Tsopelas, Panagiotis; Tuning, Niels; Ubeda Garcia, Mario; Ukleja, Artur; Ustyuzhanin, Andrey; Uwer, Ulrich; Vacca, Claudia; Vagnoni, Vincenzo; Valenti, Giovanni; Vallier, Alexis; Vazquez Gomez, Ricardo; Vazquez Regueiro, Pablo; Vázquez Sierra, Carlos; Vecchi, Stefania; Velthuis, Jaap; Veltri, Michele; Veneziano, Giovanni; Vesterinen, Mika; Viaud, Benoit; Vieira, Daniel; Vieites Diaz, Maria; Vilasis-Cardona, Xavier; Vollhardt, Achim; Volyanskyy, Dmytro; Voong, David; Vorobyev, Alexey; Vorobyev, Vitaly; Voß, Christian; de Vries, Jacco; Waldi, Roland; Wallace, Charlotte; Wallace, Ronan; Walsh, John; Wandernoth, Sebastian; Wang, Jianchun; Ward, David; Watson, Nigel; Websdale, David; Weiden, Andreas; Whitehead, Mark; Wiedner, Dirk; Wilkinson, Guy; Wilkinson, Michael; Williams, Mark Richard James; Williams, Matthew; Williams, Mike; Wilson, Fergus; Wimberley, Jack; Wishahi, Julian; Wislicki, Wojciech; Witek, Mariusz; Wormser, Guy; Wotton, Stephen; Wright, Simon; Wyllie, Kenneth; Xie, Yuehong; Xu, Zhirui; Yang, Zhenwei; Yuan, Xuhao; Yushchenko, Oleg; Zangoli, Maria; Zavertyaev, Mikhail; Zhang, Liming; Zhang, Yanxi; Zhelezov, Alexey; Zhokhov, Anatoly; Zhong, Liang

    2015-12-15

    A search is performed for heavy long-lived charged particles using 3.0 fb$^{-1}$ of pp collisions collected at $\\sqrt{s}$= 7 and 8 TeV with the LHCb detector. The search is mainly based on the response of the ring imaging Cherenkovdetectors to distinguish the heavy, slow-moving particles from muons. No evidence is found for the production of such long-lived states. The results are expressed as limits on the Drell-Yan production of pairs of long-lived particles, with both particles in the LHCb pseudorapidity acceptance, $1.8 < \\eta < 4.9$. The mass-dependent cross-section upper limits are in the range 2-4 fb (at 95\\% CL) for masses between 124 and 309 GeV/c$^2$.

  7. Dose calculations algorithm for narrow heavy charged-particle beams

    Energy Technology Data Exchange (ETDEWEB)

    Barna, E A; Kappas, C [Department of Medical Physics, School of Medicine, University of Patras (Greece); Scarlat, F [National Institute for Laser and Plasma Physics, Bucharest (Romania)

    1999-12-31

    The dose distributional advantages of the heavy charged-particles can be fully exploited by using very efficient and accurate dose calculation algorithms, which can generate optimal three-dimensional scanning patterns. An inverse therapy planning algorithm for dynamically scanned, narrow heavy charged-particle beams is presented in this paper. The irradiation `start point` is defined at the distal end of the target volume, right-down, in a beam`s eye view. The peak-dose of the first elementary beam is set to be equal to the prescribed dose in the target volume, and is defined as the reference dose. The weighting factor of any Bragg-peak is determined by the residual dose at the point of irradiation, calculated as the difference between the reference dose and the cumulative dose delivered at that point of irradiation by all the previous Bragg-peaks. The final pattern consists of the weighted Bragg-peaks irradiation density. Dose distributions were computed using two different scanning steps equal to 0.5 mm, and 1 mm respectively. Very accurate and precise localized dose distributions, conform to the target volume, were obtained. (authors) 6 refs., 3 figs.

  8. Heavy particle transport in sputtering systems

    Science.gov (United States)

    Trieschmann, Jan

    2015-09-01

    This contribution aims to discuss the theoretical background of heavy particle transport in plasma sputtering systems such as direct current magnetron sputtering (dcMS), high power impulse magnetron sputtering (HiPIMS), or multi frequency capacitively coupled plasmas (MFCCP). Due to inherently low process pressures below one Pa only kinetic simulation models are suitable. In this work a model appropriate for the description of the transport of film forming particles sputtered of a target material has been devised within the frame of the OpenFOAM software (specifically dsmcFoam). The three dimensional model comprises of ejection of sputtered particles into the reactor chamber, their collisional transport through the volume, as well as deposition of the latter onto the surrounding surfaces (i.e. substrates, walls). An angular dependent Thompson energy distribution fitted to results from Monte-Carlo simulations is assumed initially. Binary collisions are treated via the M1 collision model, a modified variable hard sphere (VHS) model. The dynamics of sputtered and background gas species can be resolved self-consistently following the direct simulation Monte-Carlo (DSMC) approach or, whenever possible, simplified based on the test particle method (TPM) with the assumption of a constant, non-stationary background at a given temperature. At the example of an MFCCP research reactor the transport of sputtered aluminum is specifically discussed. For the peculiar configuration and under typical process conditions with argon as process gas the transport of aluminum sputtered of a circular target is shown to be governed by a one dimensional interaction of the imposed and backscattered particle fluxes. The results are analyzed and discussed on the basis of the obtained velocity distribution functions (VDF). This work is supported by the German Research Foundation (DFG) in the frame of the Collaborative Research Centre TRR 87.

  9. Heavy particle beam cancer treatment apparatus, HIMAC, and clinical trial

    International Nuclear Information System (INIS)

    Soga, Fuminori

    1994-01-01

    The clinical trial was begun in June, 1994, on the treatment of cancer patients using heavy particle beam for the first time in Japan in National Institute of Radiological Sciences. It is the result of promoting the construction of Heavy Ion Medical Accelerator in Chiba (HIMAC) with the first period construction cost of 32.6 billion yen as a part of the 10 year general strategy against cancer. This is only one facility of this kind in the world. The features of heavy particle beam as radiation therapy are the excellent concentration of dose distribution, biological effect and so on. The nuclides to be used are those having the atomic number from helium to argon. The acceleration energy of ions was set at 800 MeV per nucleon so as to reach 30 cm in human bodies. The beam intensity is 5 Gy/min to finish irradiation within 1 min. The maximum irradiation field is 22 cm in diameter. The specification of the HIMAC accelerator is summarized. The Penning Ionization Gauge and the electron cyclotron resonance ion sources were installed for the reliability. The radio frequency quadrupole linear accelerator is suitable to accelerate low velocity, high intensity beam. Two synchrotrons of 41 m mean diameter are installed. High energy beam transport system, irradiation equipment, and the clinical trial are reported. (K.I.)

  10. Heavy-ion-induced bystander killing of human lung cancer cells. Role of gap junctional intercellular communication

    International Nuclear Information System (INIS)

    Harada, Kosaku; Nonaka, Tetsuo; Hamada, Nobuyuki; Sakurai, Hideyuki; Hasegawa, Masatoshi; Kobayashi, Yasuhiko; Nakano, Takashi; Funayama, Tomoo; Kakizaki, Takehiko

    2009-01-01

    The aim of the present study was to clarify the mechanisms of cell death induced by heavy-ion irradiation focusing on the bystander effect in human lung cancer A549 cells. In microbeam irradiation, each of 1, 5, and 25 cells under confluent cell conditions was irradiated with 1, 5, or 10 particles of carbon ions (220 MeV), and then the surviving fraction of the population was measured by a clonogenic assay in order to investigate the bystander effect of heavy-ions. In this experiment, the limited number of cells (0.0001-0.002%, 5-25 cells) under confluent cell conditions irradiated with 5 or 10 carbon ions resulted in an exaggerated 8-14% increase in cell death by clonogenic assay. However, these overshooting responses were not observed under exponentially growing cell conditions. Furthermore, these responses were inhibited in cells treated with an inhibitor of gap junctional intercellular communication (GJIC), whereas they were markedly enhanced by the addition of a stimulator of GJIC. The present results suggest that bystander cell killing by heavy-ions was induced mainly by direct cell-to-cell communication, such as GJIC, which might play important roles in bystander responses. (author)

  11. Heavy charged particle therapy

    International Nuclear Information System (INIS)

    Mizoe, Jun-etsu

    1995-01-01

    A pilot study of heavy charged particles with heavy ion medical accelerator in Chiba (HIMAC) for advanced H and N cancer has been carried out from June 1994 at National Institute of Radiological Sciences (NIRS). As of the beginning of August 1994, three patients were treated by 290 MeV carbon ions. The patients had adenocarcinoma of the cheek mucosa, squamous cell carcinoma of the ethmoid sinus and adenoid cystic carcinoma of the sublingual gland. Patients were immobilized by individual head coach and thermosplint facial shell. Individual collimators and bolus were also prepared for each ports. Dose fractionation for the initial pilot study group was 16.2 GyE/18 fractions/6 weeks, which would be equivalent to standard fractionation of 60.0 Gy/30 fractions/6 weeks with photons. This dose fractionation was considered to be 20% lesser than 75 GyE/37.5 fractions/7.5 weeks, which is estimated to be maximum tolerance dose for advanced H and N cancers. HIMAC worked well and there was no major trouble causing any treatment delay. Acute skin reactions of 3 patients were 2 cases of bright erythema with patchy moist desquamation and one of dull erythema, which were evaluated as equivalent reaction with irradiated dose. Acute mucosa reactions appeared to have lesser reaction than predicted mucositis. Tumor reactions of three patients were partial reaction (PR) at the end of treatment and nearly complete remission (CR) after 6 months of treatment. From October 1994, we started to treat patients with advanced H and N cancer with 10% high dose than previous dose. And new candidates of pilot study with non small cell lung cancer, brain tumor and carcinoma of the tongue were entered into pilot study. At the end of February 1995, a total of 21 patients were treated by carbon ions. (J.P.N.)

  12. Three- and two-point one-loop integrals in heavy particle effective theories

    International Nuclear Information System (INIS)

    Bouzas, A.O.

    2000-01-01

    We give a complete analytical computation of three- and two-point loop integrals occurring in heavy particle theories, involving a velocity change, for arbitrary real values of the external masses and residual momenta. (orig.)

  13. Search for long-lived heavy charged particles using a ring imaging Cherenkov technique at LHCb.

    Science.gov (United States)

    Aaij, R; Adeva, B; Adinolfi, M; Affolder, A; Ajaltouni, Z; Akar, S; Albrecht, J; Alessio, F; Alexander, M; Ali, S; Alkhazov, G; Alvarez Cartelle, P; Alves, A A; Amato, S; Amerio, S; Amhis, Y; An, L; Anderlini, L; Anderson, J; Andreotti, M; Andrews, J E; Appleby, R B; Aquines Gutierrez, O; Archilli, F; d'Argent, P; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Baalouch, M; Bachmann, S; Back, J J; Badalov, A; Baesso, C; Baldini, W; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Batozskaya, V; Battista, V; Bay, A; Beaucourt, L; Beddow, J; Bedeschi, F; Bediaga, I; Bel, L J; Belyaev, I; Ben-Haim, E; Bencivenni, G; Benson, S; Benton, J; Berezhnoy, A; Bernet, R; Bertolin, A; Bettler, M-O; van Beuzekom, M; Bien, A; Bifani, S; Bird, T; Birnkraut, A; Bizzeti, A; Blake, T; Blanc, F; Blouw, J; Blusk, S; Bocci, V; Bondar, A; Bondar, N; Bonivento, W; Borghi, S; Borgia, A; Borsato, M; Bowcock, T J V; Bowen, E; Bozzi, C; Brett, D; Britsch, M; Britton, T; Brodzicka, J; Brook, N H; Bursche, A; Buytaert, J; Cadeddu, S; Calabrese, R; Calvi, M; Calvo Gomez, M; Campana, P; Campora Perez, D; Capriotti, L; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carniti, P; Carson, L; Carvalho Akiba, K; Casanova Mohr, R; Casse, G; Cassina, L; Castillo Garcia, L; Cattaneo, M; Cauet, Ch; Cavallero, G; Cenci, R; Charles, M; Charpentier, Ph; Chefdeville, M; Chen, S; Cheung, S F; Chiapolini, N; Chrzaszcz, M; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Coco, V; Cogan, J; Cogneras, E; Cogoni, V; Cojocariu, L; Collazuol, G; Collins, P; Comerma-Montells, A; Contu, A; Cook, A; Coombes, M; Coquereau, S; Corti, G; Corvo, M; Counts, I; Couturier, B; Cowan, G A; Craik, D C; Crocombe, A; Cruz Torres, M; Cunliffe, S; Currie, R; D'Ambrosio, C; Dalseno, J; David, P N Y; Davis, A; De Bruyn, K; De Capua, S; De Cian, M; De Miranda, J M; De Paula, L; De Silva, W; De Simone, P; Dean, C T; Decamp, D; Deckenhoff, M; Del Buono, L; Déléage, N; Derkach, D; Deschamps, O; Dettori, F; Dey, B; Di Canto, A; Di Ruscio, F; Dijkstra, H; Donleavy, S; Dordei, F; Dorigo, M; Dosil Suárez, A; Dossett, D; Dovbnya, A; Dreimanis, K; Dujany, G; Dupertuis, F; Durante, P; Dzhelyadin, R; Dziurda, A; Dzyuba, A; Easo, S; Egede, U; Egorychev, V; Eidelman, S; Eisenhardt, S; Eitschberger, U; Ekelhof, R; Eklund, L; El Rifai, I; Elsasser, Ch; Ely, S; Esen, S; Evans, H M; Evans, T; Falabella, A; Färber, C; Farinelli, C; Farley, N; Farry, S; Fay, R; Ferguson, D; Fernandez Albor, V; Ferrari, F; Ferreira Rodrigues, F; Ferro-Luzzi, M; Filippov, S; Fiore, M; Fiorini, M; Firlej, M; Fitzpatrick, C; Fiutowski, T; Fol, P; Fontana, M; Fontanelli, F; Forty, R; Francisco, O; Frank, M; Frei, C; Frosini, M; Fu, J; Furfaro, E; Gallas Torreira, A; Galli, D; Gallorini, S; Gambetta, S; Gandelman, M; Gandini, P; Gao, Y; García Pardiñas, J; Garofoli, J; Garra Tico, J; Garrido, L; Gascon, D; Gaspar, C; Gauld, R; Gavardi, L; Gazzoni, G; Geraci, A; Gerick, D; Gersabeck, E; Gersabeck, M; Gershon, T; Ghez, Ph; Gianelle, A; Gianì, S; Gibson, V; Giubega, L; Gligorov, V V; Göbel, C; Golubkov, D; Golutvin, A; Gomes, A; Gotti, C; Grabalosa Gándara, M; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graverini, E; Graziani, G; Grecu, A; Greening, E; Gregson, S; Griffith, P; Grillo, L; Grünberg, O; Gui, B; Gushchin, E; Guz, Yu; Gys, T; Hadjivasiliou, C; Haefeli, G; Haen, C; Haines, S C; Hall, S; Hamilton, B; Hampson, T; Han, X; Hansmann-Menzemer, S; Harnew, N; Harnew, S T; Harrison, J; He, J; Head, T; Heijne, V; Hennessy, K; Henrard, P; Henry, L; Hernando Morata, J A; van Herwijnen, E; Heß, M; Hicheur, A; Hill, D; Hoballah, M; Hombach, C; Hulsbergen, W; Humair, T; Hussain, N; Hutchcroft, D; Hynds, D; Idzik, M; Ilten, P; Jacobsson, R; Jaeger, A; Jalocha, J; Jans, E; Jawahery, A; Jing, F; John, M; Johnson, D; Jones, C R; Joram, C; Jost, B; Jurik, N; Kandybei, S; Kanso, W; Karacson, M; Karbach, T M; Karodia, S; Kelsey, M; Kenyon, I R; Kenzie, M; Ketel, T; Khanji, B; Khurewathanakul, C; Klaver, S; Klimaszewski, K; Kochebina, O; Kolpin, M; Komarov, I; Koopman, R F; Koppenburg, P; Kravchuk, L; Kreplin, K; Kreps, M; Krocker, G; Krokovny, P; Kruse, F; Kucewicz, W; Kucharczyk, M; Kudryavtsev, V; Kurek, K; Kvaratskheliya, T; La Thi, V N; Lacarrere, D; Lafferty, G; Lai, A; Lambert, D; Lambert, R W; Lanfranchi, G; Langenbruch, C; Langhans, B; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Lees, J P; Lefèvre, R; Leflat, A; Lefrançois, J; Leroy, O; Lesiak, T; Leverington, B; Li, Y; Likhomanenko, T; Liles, M; Lindner, R; Linn, C; Lionetto, F; Liu, B; Lohn, S; Longstaff, I; Lopes, J H; Lucchesi, D; Luo, H; Lupato, A; Luppi, E; Lupton, O; Machefert, F; Machikhiliyan, I V; Maciuc, F; Maev, O; Malde, S; Malinin, A; Manca, G; Mancinelli, G; Manning, P; Mapelli, A; Maratas, J; Marchand, J F; Marconi, U; Marin Benito, C; Marino, P; Märki, R; Marks, J; Martellotti, G; Martinelli, M; Martinez Santos, D; Martinez Vidal, F; Martins Tostes, D; Massafferri, A; Matev, R; Mathe, Z; Matteuzzi, C; Mauri, A; Maurin, B; Mazurov, A; McCann, M; McCarthy, J; McNab, A; McNulty, R; McSkelly, B; Meadows, B; Meier, F; Meissner, M; Merk, M; Milanes, D A; Minard, M N; Mitzel, D S; Molina Rodriguez, J; Monteil, S; Morandin, M; Morawski, P; Mordà, A; Morello, M J; Moron, J; Morris, A B; Mountain, R; Muheim, F; Müller, J; Müller, K; Müller, V; Mussini, M; Muster, B; Naik, P; Nakada, T; Nandakumar, R; Nasteva, I; Needham, M; Neri, N; Neubert, S; Neufeld, N; Neuner, M; Nguyen, A D; Nguyen, T D; Nguyen-Mau, C; Niess, V; Niet, R; Nikitin, N; Nikodem, T; Novoselov, A; O'Hanlon, D P; Oblakowska-Mucha, A; Obraztsov, V; Ogilvy, S; Okhrimenko, O; Oldeman, R; Onderwater, C J G; Osorio Rodrigues, B; Otalora Goicochea, J M; Otto, A; Owen, P; Oyanguren, A; Palano, A; Palombo, F; Palutan, M; Panman, J; Papanestis, A; Pappagallo, M; Pappalardo, L L; Parkes, C; Passaleva, G; Patel, G D; Patel, M; Patrignani, C; Pearce, A; Pellegrino, A; Penso, G; Pepe Altarelli, M; Perazzini, S; Perret, P; Pescatore, L; Petridis, K; Petrolini, A; Picatoste Olloqui, E; Pietrzyk, B; Pilař, T; Pinci, D; Pistone, A; Playfer, S; Plo Casasus, M; Poikela, T; Polci, F; Poluektov, A; Polyakov, I; Polycarpo, E; Popov, A; Popov, D; Popovici, B; Potterat, C; Price, E; Price, J D; Prisciandaro, J; Pritchard, A; Prouve, C; Pugatch, V; Puig Navarro, A; Punzi, G; Qian, W; Quagliani, R; Rachwal, B; Rademacker, J H; Rakotomiaramanana, B; Rama, M; Rangel, M S; Raniuk, I; Rauschmayr, N; Raven, G; Redi, F; Reichert, S; Reid, M M; Dos Reis, A C; Ricciardi, S; Richards, S; Rihl, M; Rinnert, K; Rives Molina, V; Robbe, P; Rodrigues, A B; Rodrigues, E; Rodriguez Perez, P; Roiser, S; Romanovsky, V; Romero Vidal, A; Rotondo, M; Rouvinet, J; Ruf, T; Ruiz, H; Ruiz Valls, P; Saborido Silva, J J; Sagidova, N; Sail, P; Saitta, B; Salustino Guimaraes, V; Sanchez Mayordomo, C; Sanmartin Sedes, B; Santacesaria, R; Santamarina Rios, C; Santovetti, E; Sarti, A; Satriano, C; Satta, A; Saunders, D M; Savrina, D; Schiller, M; Schindler, H; Schlupp, M; Schmelling, M; Schmelzer, T; Schmidt, B; Schneider, O; Schopper, A; Schune, M H; Schwemmer, R; Sciascia, B; Sciubba, A; Semennikov, A; Sepp, I; Serra, N; Serrano, J; Sestini, L; Seyfert, P; Shapkin, M; Shapoval, I; Shcheglov, Y; Shears, T; Shekhtman, L; Shevchenko, V; Shires, A; Silva Coutinho, R; Simi, G; Sirendi, M; Skidmore, N; Skillicorn, I; Skwarnicki, T; Smith, E; Smith, E; Smith, J; Smith, M; Snoek, H; Sokoloff, M D; Soler, F J P; Soomro, F; Souza, D; Souza De Paula, B; Spaan, B; Spradlin, P; Sridharan, S; Stagni, F; Stahl, M; Stahl, S; Steinkamp, O; Stenyakin, O; Sterpka, F; Stevenson, S; Stoica, S; Stone, S; Storaci, B; Stracka, S; Straticiuc, M; Straumann, U; Stroili, R; Sun, L; Sutcliffe, W; Swientek, K; Swientek, S; Syropoulos, V; Szczekowski, M; Szczypka, P; Szumlak, T; T'Jampens, S; Tekampe, T; Teklishyn, M; Tellarini, G; Teubert, F; Thomas, C; Thomas, E; van Tilburg, J; Tisserand, V; Tobin, M; Todd, J; Tolk, S; Tomassetti, L; Tonelli, D; Topp-Joergensen, S; Torr, N; Tournefier, E; Tourneur, S; Trabelsi, K; Tran, M T; Tresch, M; Trisovic, A; Tsaregorodtsev, A; Tsopelas, P; Tuning, N; Ubeda Garcia, M; Ukleja, A; Ustyuzhanin, A; Uwer, U; Vacca, C; Vagnoni, V; Valenti, G; Vallier, A; Vazquez Gomez, R; Vazquez Regueiro, P; Vázquez Sierra, C; Vecchi, S; Velthuis, J J; Veltri, M; Veneziano, G; Vesterinen, M; Viaud, B; Vieira, D; Vieites Diaz, M; Vilasis-Cardona, X; Vollhardt, A; Volyanskyy, D; Voong, D; Vorobyev, A; Vorobyev, V; Voß, C; de Vries, J A; Waldi, R; Wallace, C; Wallace, R; Walsh, J; Wandernoth, S; Wang, J; Ward, D R; Watson, N K; Websdale, D; Weiden, A; Whitehead, M; Wiedner, D; Wilkinson, G; Wilkinson, M; Williams, M; Williams, M P; Williams, M; Wilson, F F; Wimberley, J; Wishahi, J; Wislicki, W; Witek, M; Wormser, G; Wotton, S A; Wright, S; Wyllie, K; Xie, Y; Xu, Z; Yang, Z; Yuan, X; Yushchenko, O; Zangoli, M; Zavertyaev, M; Zhang, L; Zhang, Y; Zhelezov, A; Zhokhov, A; Zhong, L

    A search is performed for heavy long-lived charged particles using 3.0 [Formula: see text] of proton-proton collisions collected at [Formula: see text][Formula: see text] 7 and 8  TeV with the LHCb detector. The search is mainly based on the response of the ring imaging Cherenkov detectors to distinguish the heavy, slow-moving particles from muons. No evidence is found for the production of such long-lived states. The results are expressed as limits on the Drell-Yan production of pairs of long-lived particles, with both particles in the LHCb pseudorapidity acceptance, [Formula: see text]. The mass-dependent cross-section upper limits are in the range 2-4 fb (at 95 % CL) for masses between 14 and 309 [Formula: see text].

  14. Effect of particle-induced displacements on the critical temperature of YBa2Cu3O7-δ

    International Nuclear Information System (INIS)

    Summers, G.P.; Burke, E.A.; Chrisey, D.B.; Nastasi, M.; Tesmer, J.R.

    1989-01-01

    The particle-induced depression of the superconducting critical temperature T c of YBa 2 Cu 3 O 7-δ is shown to be directly proportional, over seven orders of magnitude, to the nonionizing energy deposited in the lattice by primary knock-on atoms displaced by incident electrons, protons, and heavy ions. It is concluded that ΔT c is proportional only to the average number of defects produced and can therefore be predicted for any particle, energy, and fluence from a calculation of the nonionizing energy loss

  15. Large-eddy simulation of heavy particle dispersion in wall-bounded turbulent flows

    Energy Technology Data Exchange (ETDEWEB)

    Salvetti, M.V. [DICI, University of Pisa, I-56122 Pisa (Italy)

    2015-03-10

    Capabilities and accuracy issues in Lagrangian tracking of heavy particles in velocity fields obtained from large-eddy simulations (LES) of wall-bounded turbulent flows are reviewed. In particular, it is shown that, if no subgrid scale (SGS) model is added to the particle motion equations, particle preferential concentration and near-wall accumulation are significantly underestimated. Results obtained with SGS modeling for the particle motion equations based on approximate deconvolution are briefly recalled. Then, the error purely due to filtering in particle tracking in LES flow fields is singled out and analyzed. The statistical properties of filtering errors are characterized in turbulent channel flow both from an Eulerian and a Lagrangian viewpoint. Implications for stochastic SGS modeling in particle motion equations are briefly outlined.

  16. A new tagger for hadronically decaying heavy particles at the LHC

    Energy Technology Data Exchange (ETDEWEB)

    Lapsien, T.; Kogler, R.; Haller, J. [Universitaet Hamburg, Institut fuer Experimentalphysik, Hamburg (Germany)

    2016-11-15

    A new algorithm for the identification of boosted, hadronically decaying, heavy particles at the LHC is presented. The algorithm is based on the known procedure of jet clustering with variable distance parameter R and adapts the jet size to its transverse momentum p{sub T}. Subjets are found using a mass jump condition. The resulting algorithm - called Heavy Object Tagger with Variable R (HOTVR) - features little algorithmic complexity and combines jet clustering, subjet finding and rejection of soft clusters in one sequence. While the HOTVR algorithm can be used for the identification of any heavy object decaying hadronically, e.g. W, Z, H, t, or possible new heavy resonances, this paper targets specifically the tagging of boosted top quarks. The studies presented here demonstrate a stable performance of the HOTVR algorithm in a wide range of top quark p{sub T}, from low p{sub T}, where the decay products can be resolved, to the region of boosted decays at high p{sub T}. (orig.)

  17. Scale-similar clustering of heavy particles in the inertial range of turbulence

    Science.gov (United States)

    Ariki, Taketo; Yoshida, Kyo; Matsuda, Keigo; Yoshimatsu, Katsunori

    2018-03-01

    Heavy particle clustering in turbulence is discussed from both phenomenological and analytical points of view, where the -4 /3 power law of the pair-correlation function is obtained in the inertial range. A closure theory explains the power law in terms of the balance between turbulence mixing and preferential-concentration mechanism. The obtained -4 /3 power law is supported by a direct numerical simulation of particle-laden turbulence.

  18. Repair pathways for heavy ion-induced complex DNA double strand breaks

    International Nuclear Information System (INIS)

    Yajima, Hirohiko; Nakajima, Nakako; Hirakawa, Hirokazu; Murakami, Takeshi; Okayasu, Ryuichi; Fujimori, Akira

    2012-01-01

    DNA double strand break (DSB) induced by ionizing radiation (IR) is a deleterious damage leading to cell death and genome instability if not properly repaired. It is well known that DSB is repaired by two major pathways, non-homologous end-joining (NHEJ) and homologous recombination (HR). It is also known that NHEJ is dominant throughout the cell cycle after X- or gamma-ray irradiation in mammalian cells, Meanwhile, it is thought that heavy-ion radiation (e.g., carbon-ions, iron-ions) gives rise to clustered DNA damages consisting of not only strand breaks but also aberrant bases in the vicinity of DSBs (complex DSBs). Our previous work suggested that the efficiency of NHEJ is diminished for repair of complex DSBs induced by heavy-ion radiation. We thought that this difficulty in NHEJ process associated with heavy ion induced complex DNA damage might be extended to HR process in cells exposed to heavy ions. In order to find out if this notion is true or not, exposed human cells to X-rays and heavy-ions, and studied HR associated processes at the molecular level. Our result indicates that complex DSBs induced by heavy ions effectively evoke DNA end resection activity during the HR process. Together with our results, a relevant recent progress in the field of DNA DSB repair will be discussed. (author)

  19. Effects of heavy particle irradiation on central nervous system

    International Nuclear Information System (INIS)

    Nojima, Kumie; Nakadai, Taeko; Khono, Yukio

    2006-01-01

    Effects of low dose heavy particle radiation to central nervous system were studied using human embryonal carcinoma (Ntera2=NT2) and Human neuroblastoma cell (NB1). They exposed to heavy ions and X ray 80% confluent cells in culture bottles. The cells were different type about growth and differentiation in the neuron. The apoptosis profile was measured by AnnexinV-EGFP, PI stained and fluorescence-activated cell sorter (FACS). Memory and learning function of adult mice were studied using water maze test after carbon- or iron-ion irradiation. Memory functions were rapidly decreased after irradiation both ions. Iron -ion group were recovered 20 weeks after irradiation C-ion group were recovered 25 weeks after irradiation. Tier memory were still keep at over 100 weeks after irradiation. (author)

  20. Searching for squeezed particle-antiparticle correlations in high-energy heavy-ion collisions

    International Nuclear Information System (INIS)

    Padula, Sandra S.; Socolowski, O. Jr.

    2010-01-01

    Squeezed correlations of particle-antiparticle pairs were predicted to exist if the hadron masses were modified in the hot and dense medium formed in high-energy heavy-ion collisions. Although well-established theoretically, they have not yet been observed experimentally. We suggest here a clear method to search for such a signal by analyzing the squeezed correlation functions in terms of measurable quantities. We illustrate this suggestion for simulated φφ pairs at the Relativistic Heavy Ion Collider (RHIC) energies.

  1. Physical fundamentals of the application of heavy charged particles in radiotherapy

    International Nuclear Information System (INIS)

    Bueche, G.

    1977-01-01

    In the chapter 'Medical Applications' A 'Radiotherapy' of the study, the following subjects are treated in detail by various authors: Physical fundamentals of the application of heavy charged particles in radiotherapy-radiation-biological fundamentals; clinical aspects of radiotherapy with protons and negative pions; patients and clinical dosimetry. (MG) [de

  2. Problem of α-clustering levels in heavy nuclei

    International Nuclear Information System (INIS)

    Kadmenskij, V.G.; Kadmenskij, S.G.; Kurgalin, S.D.; Furman, V.I.

    1982-01-01

    From the optical model analysis of elastic scattering and absorption cross sections of α-particles including the (n,α) reaction induced by resonance neutrons it may be concluded that the conception of black nucleus is valid for α-particles. It was shown that the magnitudes of α-particle surface spectroscopic factors did not exceed 10sup(-2) for all the known α-transitions both in spherical and deformed heavy nuclei accounting for the ambiguities of the optical model potential. The possibilities of extracting the α-particles form factors of low-lying nuclear states from α-transfer reaction data are considered. From all the data considered it is concluded that there is no evidence for the revealing of α-clustering levels in heavy nuclei. (author)

  3. Physics and radiobiology of heavy charged particles in relation to the use of ion beams for therapy

    International Nuclear Information System (INIS)

    Kraft, G.; Haberer, T.; Schardt, D.; Scholz, M.

    1993-07-01

    Heavy charged particles are the most advanced tool of an external subcutane radiotherapy of deep seated tumors. Small angular- and lateral-scattering and the increase of the energy deposition with penetration depth are the physical basis for a more efficient tumor targeting. High biological efficiency in the tumor is the prerequisite for a successful treatment of tumors radioresistant against sparsely ionizing radiation. The possibility to perform target conform irradiation and to control the achieved/actual distribution using PET techniques guarantees that biological highly efficient stepping particles can be restricted to the tumor volume only. Although the physical and radiobiological properties of ion beams are very favourable for therapy, the necessity to produce these particles in an accelerator restricts a general application of heavy ions up to now. Presently the heavy ion accelerator SIS at GSI is the only source of heavy ion beams, sufficient in energy and intensity for therapy. A therapy unit is in preparation at GSI, the status of this project is given at the end of the paper. (orig.)

  4. Hard scattering contribution to particle production in high energy heavy-ion collisions

    International Nuclear Information System (INIS)

    Pareek, Pooja; Mishra, Aditya Nath; Sahoo, Pragati; Sahoo, Raghunath

    2014-01-01

    Global observables like the multiplicity of produced charged particles and transverse energy, are the key observables used to characterize the properties of the matter created in heavy-ion collisions. In order to study the dependence of the charged particle density on colliding system, center of mass energy and collision centrality, there have been measurements starting few GeV to TeV energies at LHC. There is a need to understand the particle production contribution coming from the QCD hard processes, which scale with number of binary nucleon-nucleon collisions, N coll and soft processes scaling with number of participant nucleons, N part

  5. Epigenetic Analysis of Heavy-ion Radiation Induced Bystander Effects in Mice

    Science.gov (United States)

    Zhang, Meng; Sun, Yeqing; Cui, Changna; Xue, Bei

    Abstract: Radiation-induced bystander effect was defined as the induction of damage in neighboring non-hit cells by signals released from directly-irradiated cells. Recently, low dose of high LET radiation induced bystander effects in vivo have been reported more and more. It has been indicated that radiation induced bystander effect was localized not only in bystander tissues but also in distant organs. Genomic, epigenetic and proteomics plays significant roles in regulating heavy-ion radiation stress responses in mice. To identify the molecular mechanism that underlies bystander effects of heavy-ion radiation, the male Balb/c and C57BL mice were exposed head-only to 40, 200, 2000mGy dose of (12) C heavy-ion radiation, while the rest of the animal body was shielded. Directly radiation organ ear and the distant organ liver were detected on 1h, 6h, 12h and 24h after radiation, respectively. Methylation-sensitive amplification polymorphism (MSAP) was used to monitor the level of polymorphic genomic DNA methylation changed with dose and time effects. The results show that heavy-ion irradiated mouse head could induce genomic DNA methylation changes significantly in both the directly radiation organ ear and the distant organ liver. The percent of DNA methylation changes were time-dependent and tissue-specific. Demethylation polymorphism rate was highest separately at 1 h in 200 mGy and 6 h in 2000 mGy after irradiation. The global DNA methylation changes tended to occur in the CG sites. The results illustrated that genomic methylation changes of heavy ion radiation-induced bystander effect in liver could be obvious 1 h after radiation and achieved the maximum at 6 h, while the changes could recover gradually at 12 h. The results suggest that mice head exposed to heavy-ion radiation can induce damage and methylation pattern changed in both directly radiation organ ear and distant organ liver. Moreover, our findings are important to understand the molecular mechanism of

  6. Attempts of local irradiation of cells by microbeam. From ultraviolet to heavy particles

    Energy Technology Data Exchange (ETDEWEB)

    Kobayashi, Yasuhiko [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment

    2002-03-01

    This review describes the history of attempts of local irradiation of cells by microbeam and present status of the study. Local irradiation of cells was attempted as early as in 1912 with use of short {alpha}-particle range and of focused UV beams. After the war, laser microbeams were then developed for microsurgery in embryology. In addition, microbeams of electron generated from the gun and of X-ray collimated were developed. In 1950s, the electron microbeam was generated from Van de Graaff accelerator in Chicago University and proton, deuteron and He-ion microbeams from the cyclotron, in BNL. In 1980s, Gesellschaft fuer Schwerionenforshung (Germany) used heavy ion microbeams from C to U generated from the linear accelerator and PNL, proton to {sup 4}He-ion microbeams from the tandem-electrostatic accelerator. At present in 2002, the equipments for microbeam for cell irradiation are the Van de Graaff accelerators in Gray Cancer Institute (England) and in Columbia University, and the cyclotron in TIARA in Japan. The purpose of the study in TIARA is to develop a system to generate heavy particle microbeams for cell irradiation for analysis of the biological effect of ultra-low fluence, high LET heavy particles like the galactic cosmic ray. Recently, the CHO-KI cell nucleus is irradiated by {sup 40}Ar and {sup 20}Ne ions. (K.H.)

  7. Attempts of local irradiation of cells by microbeam. From ultraviolet to heavy particles

    International Nuclear Information System (INIS)

    Kobayashi, Yasuhiko

    2002-01-01

    This review describes the history of attempts of local irradiation of cells by microbeam and present status of the study. Local irradiation of cells was attempted as early as in 1912 with use of short α-particle range and of focused UV beams. After the war, laser microbeams were then developed for microsurgery in embryology. In addition, microbeams of electron generated from the gun and of X-ray collimated were developed. In 1950s, the electron microbeam was generated from Van de Graaff accelerator in Chicago University and proton, deuteron and He-ion microbeams from the cyclotron, in BNL. In 1980s, Gesellschaft fuer Schwerionenforshung (Germany) used heavy ion microbeams from C to U generated from the linear accelerator and PNL, proton to 4 He-ion microbeams from the tandem-electrostatic accelerator. At present in 2002, the equipments for microbeam for cell irradiation are the Van de Graaff accelerators in Gray Cancer Institute (England) and in Columbia University, and the cyclotron in TIARA in Japan. The purpose of the study in TIARA is to develop a system to generate heavy particle microbeams for cell irradiation for analysis of the biological effect of ultra-low fluence, high LET heavy particles like the galactic cosmic ray. Recently, the CHO-KI cell nucleus is irradiated by 40 Ar and 20 Ne ions. (K.H.)

  8. Brain signaling and behavioral responses induced by exposure to (56)Fe-particle radiation

    Science.gov (United States)

    Denisova, N. A.; Shukitt-Hale, B.; Rabin, B. M.; Joseph, J. A.

    2002-01-01

    Previous experiments have demonstrated that exposure to 56Fe-particle irradiation (1.5 Gy, 1 GeV) produced aging-like accelerations in neuronal and behavioral deficits. Astronauts on long-term space flights will be exposed to similar heavy-particle radiations that might have similar deleterious effects on neuronal signaling and cognitive behavior. Therefore, the present study evaluated whether radiation-induced spatial learning and memory behavioral deficits are associated with region-specific brain signaling deficits by measuring signaling molecules previously found to be essential for behavior [pre-synaptic vesicle proteins, synaptobrevin and synaptophysin, and protein kinases, calcium-dependent PRKCs (also known as PKCs) and PRKA (PRKA RIIbeta)]. The results demonstrated a significant radiation-induced increase in reference memory errors. The increases in reference memory errors were significantly negatively correlated with striatal synaptobrevin and frontal cortical synaptophysin expression. Both synaptophysin and synaptobrevin are synaptic vesicle proteins that are important in cognition. Striatal PRKA, a memory signaling molecule, was also significantly negatively correlated with reference memory errors. Overall, our findings suggest that radiation-induced pre-synaptic facilitation may contribute to some previously reported radiation-induced decrease in striatal dopamine release and for the disruption of the central dopaminergic system integrity and dopamine-mediated behavior.

  9. Bibliography of molecular dissociation in heavy particle collisions, 1950--75

    Energy Technology Data Exchange (ETDEWEB)

    McDaniel, E.W.; Barnett, C.F.; Crandall, D.H.; Gilbody, H.B.; Kirkpatrick, M.I.; Phaneuf, R.A.; Thomas, E.W.

    1979-02-01

    This annotated bibliography lists published work on molecular dissociation in heavy particle collisions for the period 1950 to 1975. Sources include scientific journals, abstract compilations, conference proceedings, books, and reports. The bibliography is arranged alphabetically by author. Each entry indicates whether the work was experimental or theoretical, what energy range was covered, and what reactants were investigated. Following the bibliographical listing are indexes of reactants and authors.

  10. Bibliography of molecular dissociation in heavy particle collisions, 1950--75

    International Nuclear Information System (INIS)

    McDaniel, E.W.; Barnett, C.F.; Crandall, D.H.; Gilbody, H.B.; Kirkpatrick, M.I.; Phaneuf, R.A.; Thomas, E.W.

    1979-02-01

    This annotated bibliography lists published work on molecular dissociation in heavy particle collisions for the period 1950 to 1975. Sources include scientific journals, abstract compilations, conference proceedings, books, and reports. The bibliography is arranged alphabetically by author. Each entry indicates whether the work was experimental or theoretical, what energy range was covered, and what reactants were investigated. Following the bibliographical listing are indexes of reactants and authors

  11. Bibliography of electron transfer in heavy particle collisions, 1950--1975

    International Nuclear Information System (INIS)

    Hawthorne, S.W.; Barnett, C.F.; Crandall, D.H.; Gilbody, H.B.; Kirkpatrick, M.I.; McDaniel, E.; Phaneuf, R.A.; Thomas, E.W.

    1979-02-01

    This annotated bibliography lists published work on electron transfer in heavy particle collisions for the period 1950 to 1975. Sources include scientific journals, abstract compilations, conference proceedings, books, and reports. The bibliography is arranged alphabetically by author. Each entry indicates whether the work was experimental or theoretical, what energy range was covered, and what reactants were investigated. Following the bibliographical listing are indexes of reactants and authors

  12. Numerical analysis of energy density and particle density in high energy heavy-ion collisions

    International Nuclear Information System (INIS)

    Fu Yuanyong; Lu Zhongdao

    2004-01-01

    Energy density and particle density in high energy heavy-ion collisions are calculated with infinite series expansion method and Gauss-Laguerre formulas in numerical integration separately, and the results of these two methods are compared, the higher terms and linear terms in series expansion are also compared. The results show that Gauss-Laguerre formulas is a good method in calculations of high energy heavy-ion collisions. (author)

  13. (d,p)-transfer induced fission of heavy radioactive beams

    CERN Document Server

    Veselsky, Martin

    2012-01-01

    (d,p)-transfer induced fission is proposed as a tool to study low energy fission of exotic heavy nuclei. Primary goal is to directly determine the fission barrier height of proton-rich fissile nuclei, preferably using the radio-active beams of isotopes of odd elements, and thus confirm or exclude the low values of fission barrier heights, typically extracted using statistical calculations in the compound nucleus reactions at higher excitation energies. Calculated fission cross sections in transfer reactions of the radioactive beams show sufficient sensitivity to fission barrier height. In the probable case that fission rates will be high enough, mass asymmetry of fission fragments can be determined. Results will be relevant for nuclear astrophysics and for production of super-heavy nuclei. Transfer induced fission offers a possibility for systematic study the low energy fission of heavy exotic nuclei at the ISOLDE.

  14. CHARGE-2/C, Flux and Dose Behind Shield from Electron, Proton, Heavy Particle Irradiation

    International Nuclear Information System (INIS)

    Ucker, W.R.; Lilley, J.R.

    1994-01-01

    1 - Description of problem or function: The CHARGE code computes flux spectra, dose and other response rates behind a multilayered spherical or infinite planar shield exposed to isotopic fluxes of electrons, protons and heavy charged particles. The doses, or other responses, to electron, primary proton, heavy particle, electron Bremsstrahlung, secondary proton, and secondary neutron radiations are calculated as a function of penetration into the shield; the materials of each layer may be mixtures of elements contained in the accompanying data library, or supplied by the user. The calculation may optionally be halted before the entire shield is traversed by specifying a minimum total dose rate; the computation stops when the dose drops below this value. The ambient electron, proton and heavy particle spectra may be specified in tabular or functional form. These incident charged particle spectra are divided into energy bands or groups, the number or spacing of which are controlled by input data. The variation of the group boundary energies and group spectra as a function of shield penetration uniquely determines charged particle dose rates and secondary particle production rates. The charged particle shielding calculation is essentially the integration of the range- energy equation which expresses the variation of particle energy wit distance travelled. 2 - Method of solution: The 'straight-ahead' approximation is used throughout, that is the changes in particle direction of motion due to elastic scattering are ignored. This approximation is corrected, in the case of electrons, by applying transmission factors obtained from Monte Carlo calculations. Inelastic scattering between protons and the shielding material is assumed to produce two classes of secondaries 1) Cascade protons and neutrons, emitted in the same direction as the primaries 2) Evaporation neutrons, emitted isotropically. The transmission of secondary protons is analyzed in exactly the same way as the

  15. Removal of heavy metals using bentonite supported nano-zero valent iron particles

    Science.gov (United States)

    Zarime, Nur Aishah; Yaacob, Wan Zuhari Wan; Jamil, Habibah

    2018-04-01

    This study reports the composite nanoscale zero-valent iron (nZVI) which was successfully synthesized using low cost natural clay (bentonite). Bentonite composite nZVI (B-nZVI) was introduced to reduce the agglomeration of nZVI particles, thus will used for heavy metals treatment. The synthesized material was analyzed using physical, mineralogy and morphology analysis such as Brunnaer-Emmett-Teller (BET) surface area, Field Emission Scanning Electron Microscopy (FESEM), X-Ray Diffraction (XRD), Fourier Transform Infrared (FTIR) and X-ray Photoelectron Spectroscopy (XPS). The batch adsorption test of Bentonite and B-nZVI with heavy metals solutions (Pb, Cu, Cd, Co, Ni and Zn) was also conducted to determine their effectiveness in removing heavy metals. Through Batch test, B-nZVI shows the highest adsorption capacity (qe= 50.25 mg/g) compared to bentonite (qe= 27.75 mg/g). This occurred because B-nZVI can reduce aggregation of nZVI, dispersed well in bentonite layers thus it can provide more sites for adsorbing heavy metals.

  16. Emission of high-energy, light particles from intermediate-energy heavy-ion reactions

    International Nuclear Information System (INIS)

    Ball, J.B.; Auble, R.L.

    1982-01-01

    One of the early surprises in examining reaction products from heavy ion reactions at 10 MeV/nucleon and above was the large yield of light particles emitted and the high energies to which the spectra of these particles extended. The interpretation of the origin of the high energy light ions has evolved from a picture of projectile excitation and subsequent evaporation to one of pre-equilibrium (or nonequilibrium) emission. The time scale for particle emission has thus moved from one that occurs following the initial collision to one that occurs at the very early stages of the collision. Research at ORNL on this phenomenon is reviewed

  17. Heavy ion transfer reactions

    International Nuclear Information System (INIS)

    Weisser, D.C.

    1977-06-01

    To complement discussions on the role of γ rays in heavy ion induced reactions, the author discusses the role played by particle detection. Transfer reactions are part of this subject and are among those in which one infers the properties of the residual nucleus in a reaction by observing the emerging light nucleus. Inelastic scattering ought not be excluded from this subject, although no particles are transferred, because of the role it plays in multistep reactions and in fixing O.M. parameters describing the entrance channel of the reaction. Heavy ion transfer reaction studies have been under study for some years and yet this research is still in its infancy. The experimental techniques are difficult and the demands on theory rigorous. One of the main products of heavy ion research has been the thrust to re-examine the assumptions of reaction theory and now include many effects neglected for light ion analysis. This research has spurred the addition of multistep processes to simple direct processes and coupled channel calculations. (J.R.)

  18. Swift Heavy Ion Induced Modification of Aliphatic Polymers

    OpenAIRE

    Hossain, Umme Habiba

    2015-01-01

    In this thesis, the high energy heavy ion induced modification of aliphatic polymers is studied. Two polymer groups, namely polyvinyl polymers (PVF, PVAc, PVA and PMMA) and fluoropolymers (PVDF, ETFE, PFA and FEP) were used in this work. Polyvinyl polymers were investigated since they will be used as insulating materials in the superconducting magnets of the new ion accelerators of the planned International Facility for Antiproton and Ion Research (FAIR) at the GSI Helmholtz-Centre of Heavy I...

  19. Heavy particle signatures in cosmological correlation functions with tensor modes

    Science.gov (United States)

    Saito, Ryo; Kubota, Takahiro

    2018-06-01

    We explore the possibility to make use of cosmological data to look for signatures of unknown heavy particles whose masses are on the order of the Hubble parameter during the time of inflation. To be more specific we take up the quasi-single field inflation model, in which the isocurvaton σ is supposed to be the heavy particle. We study correlation functions involving both scalar (ζ ) and tensor (γ ) perturbations and search for imprints of the σ-particle effects. We make use of the technique of the effective field theory for inflation to derive the ζ σ and γ ζ σ couplings. With these couplings we compute the effects due to σ to the power spectrum langle ζ ζ rangle and correlations langle γs ζ ζ rangle and langle γs1 γ s2 ζ ζ rangle , where s, s1 and s2 are the polarization indices of gravitons. Numerical analyses of the σ-mass effects to these correlations are presented. It is argued that future precise observations of these correlations could make it possible to measure the σ-mass and the strength of the ζ σ and γ ζ σ couplings. As an extension to the N-graviton case we also compute the correlations langle γ s1 ... γ sN ζ ζ rangle and langle γ s1 ... ... γ s2N ζ ζ rangle and their σ-mass effects. It is suggested that larger N correlation functions are useful to probe larger σ-mass.

  20. Cell cycle delays induced by heavy ion irradiation of synchronous mammalian cells

    International Nuclear Information System (INIS)

    Scholz, M.; Kraft-Weyrather, W.; Ritter, S.; Kraft, G.

    1994-01-01

    Cell cycle delays in V79 Chinese hamster cells induced by heavy ion exposure have been investigated using flow cytometry. Synchronous cell populations in G 1 -, S- and late-S/G 2 M-phase were used. Cells were irradiated with particles from Z = 10 (neon) up to Z = 96 (uranium) in the energy range from 2.4 to 17.4 MeV/u and the LET range from 415 to 16225 keV/μm at the UNILAC at GSI, Darmstadt. For comparison, experiments with 250 kV X-rays were performed. For light particles like neon, cell cycle perturbations comparable to those after X-ray irradiation were found, and with increasing LET an increasing delay per particle traversal was observed. For the highest LET-values, extended delays in G 1 -, S- and G 2 M-phase were detected immediately after irradiation. A large fraction of the cells remained in S-phase or G 2 M-phase up to 48 h or longer after irradiation. No significant cell age dependence of cycle delays was detected for the very high LET values. In addition to cell cycle delays, two effects related to the DNA-content as determined by flow cytometry were found after irradiation with very high LET particles, which were attributed to cell fusion and to drastic morphological changes of the cells. Estimations based on the dose deposited by a single particle hit in the cell nucleus and the actual number of hits show, that the basic trend of the experimental results can be explained by the stochastic properties of particle radiation. (orig.)

  1. Search for Heavy Stable and Long-Lived Particles in $e^{+}e^{-}$ Collisions at $\\sqrt{s}$=189 GeV

    CERN Document Server

    Abreu, P.; Adye, T.; Adzic, P.; Albrecht, Z.; Alderweireld, T.; Alekseev, G.D.; Alemany, R.; Allmendinger, T.; Allport, P.P.; Almehed, S.; Amaldi, U.; Amapane, N.; Amato, S.; Anassontzis, E.G.; Andersson, P.; Andreazza, A.; Andringa, S.; Antilogus, P.; Apel, W.D.; Arnoud, Y.; Asman, B.; Augustin, J.E.; Augustinus, A.; Baillon, P.; Bambade, P.; Barao, F.; Barbiellini, G.; Barbier, R.; Bardin, Dmitri Yu.; Barker, G.J.; Baroncelli, A.; Battaglia, M.; Baubillier, M.; Becks, K.H.; Begalli, M.; Behrmann, A.; Beilliere, P.; Belokopytov, Yu.; Belous, K.; Benekos, N.C.; Benvenuti, A.C.; Berat, C.; Berggren, M.; Bertrand, D.; Besancon, M.; Bigi, M.; Bilenky, Mikhail S.; Bizouard, M.A.; Bloch, D.; Blom, H.M.; Bonesini, M.; Boonekamp, M.; Booth, P.S.L.; Borgland, A.W.; Borisov, G.; Bosio, C.; Botner, O.; Boudinov, E.; Bouquet, B.; Bourdarios, C.; Bowcock, T.J.V.; Boyko, I.; Bozovic, I.; Bozzo, M.; Bracko, M.; Branchini, P.; Brenner, R.A.; Bruckman, P.; Brunet, J.M.; Bugge, L.; Buran, T.; Buschbeck, B.; Buschmann, P.; Cabrera, S.; Caccia, M.; Calvi, M.; Camporesi, T.; Canale, V.; Carena, F.; Carroll, L.; Caso, C.; Castillo Gimenez, M.V.; Cattai, A.; Cavallo, F.R.; Chabaud, V.; Chapkin, M.; Charpentier, P.; Checchia, P.; Chelkov, G.A.; Chierici, R.; Chliapnikov, P.; Chochula, P.; Chorowicz, V.; Chudoba, J.; Cieslik, K.; Collins, P.; Contri, R.; Cortina, E.; Cosme, G.; Cossutti, F.; Crawley, H.B.; Crennell, D.; Crepe-Renaudin, Sabine; Crosetti, G.; Cuevas Maestro, J.; Czellar, S.; Davenport, M.; Da Silva, W.; Della Ricca, G.; Delpierre, P.; Demaria, N.; De Angelis, A.; De Boer, W.; De Clercq, C.; De Lotto, B.; De Min, A.; De Paula, L.; Dijkstra, H.; Di Ciaccio, L.; Dolbeau, J.; Doroba, K.; Dracos, M.; Drees, J.; Dris, M.; Duperrin, A.; Durand, J.D.; Eigen, G.; Ekelof, T.; Ekspong, G.; Ellert, M.; Elsing, M.; Engel, J.P.; Espirito Santo, M.C.; Fanourakis, G.; Fassouliotis, D.; Fayot, J.; Feindt, M.; Ferrer, A.; Ferrer-Ribas, E.; Ferro, F.; Fichet, S.; Firestone, A.; Flagmeyer, U.; Foeth, H.; Fokitis, E.; Fontanelli, F.; Franek, B.; Frodesen, A.G.; Fruhwirth, R.; Fulda-Quenzer, F.; Fuster, J.; Galloni, A.; Gamba, D.; Gamblin, S.; Gandelman, M.; Garcia, C.; Gaspar, C.; Gaspar, M.; Gasparini, U.; Gavillet, P.; Gazis, Evangelos; Gele, D.; Geralis, T.; Ghodbane, N.; Gil Botella, Ines; Glege, F.; Gokieli, R.; Golob, B.; Gomez-Ceballos, G.; Goncalves, P.; Gonzalez Caballero, I.; Gopal, G.; Gorn, L.; Gouz, Yu.; Gracco, V.; Grahl, J.; Graziani, E.; Gris, P.; Grosdidier, G.; Grzelak, K.; Guy, J.; Haag, C.; Hahn, F.; Hahn, S.; Haider, S.; Hallgren, A.; Hamacher, K.; Hansen, J.; Harris, F.J.; Hedberg, V.; Heising, S.; Hernandez, J.J.; Herquet, P.; Herr, H.; Hessing, T.L.; Heuser, J.M.; Higon, E.; Holmgren, S.O.; Holt, P.J.; Hoorelbeke, S.; Houlden, M.; Hrubec, J.; Huber, M.; Huet, K.; Hughes, G.J.; Hultqvist, K.; Jackson, John Neil; Jacobsson, R.; Jalocha, P.; Janik, R.; Jarlskog, C.; Jarlskog, G.; Jarry, P.; Jean-Marie, B.; Jeans, D.; Johansson, Erik Karl; Jonsson, P.; Joram, C.; Juillot, P.; Jungermann, L.; Kapusta, Frederic; Karafasoulis, K.; Katsanevas, S.; Katsoufis, E.C.; Keranen, R.; Kernel, G.; Kersevan, B.P.; Khokhlov, Yu.A.; Khomenko, B.A.; Khovanski, N.N.; Kiiskinen, A.; King, B.; Kinvig, A.; Kjaer, N.J.; Klapp, O.; Klein, Hansjorg; Kluit, P.; Kokkinias, P.; Kostioukhine, V.; Kourkoumelis, C.; Kouznetsov, O.; Krammer, M.; Kriznic, E.; Krumstein, Z.; Kubinec, P.; Kurowska, J.; Kurvinen, K.; Lamsa, J.W.; Lane, D.W.; Lapin, V.; Laugier, J.P.; Lauhakangas, R.; Leder, G.; Ledroit, Fabienne; Lefebure, V.; Leinonen, L.; Leisos, A.; Leitner, R.; Lenzen, G.; Lepeltier, V.; Lesiak, T.; Lethuillier, M.; Libby, J.; Liebig, W.; Liko, D.; Lipniacka, A.; Lippi, I.; Loerstad, B.; Loken, J.G.; Lopes, J.H.; Lopez, J.M.; Lopez-Fernandez, R.; Loukas, D.; Lutz, P.; Lyons, L.; MacNaughton, J.; Mahon, J.R.; Maio, A.; Malek, A.; Malmgren, T.G.M.; Maltezos, S.; Malychev, V.; Mandl, F.; Marco, J.; Marco, R.; Marechal, B.; Margoni, M.; Marin, J.C.; Mariotti, C.; Markou, A.; Martinez-Rivero, C.; Martinez-Vidal, F.; Marti i Garcia, S.; Masik, J.; Mastroyiannopoulos, N.; Matorras, F.; Matteuzzi, C.; Matthiae, G.; Mazzucato, F.; Mazzucato, M.; McCubbin, M.; McKay, R.; McNulty, R.; McPherson, G.; Meroni, C.; Meyer, W.T.; Miagkov, A.; Migliore, E.; Mirabito, L.; Mitaroff, W.A.; Mjoernmark, U.; Moa, T.; Moch, M.; Moller, Rasmus; Monig, Klaus; Monge, M.R.; Moraes, D.; Moreau, X.; Morettini, P.; Morton, G.; Mueller, U.; Muenich, K.; Mulders, M.; Mulet-Marquis, C.; Muresan, R.; Murray, W.J.; Muryn, B.; Myatt, G.; Myklebust, T.; Naraghi, F.; Nassiakou, M.; Navarria, F.L.; Navas, Sergio; Nawrocki, K.; Negri, P.; Neufeld, N.; Nicolaidou, R.; Nielsen, B.S.; Niezurawski, P.; Nikolenko, M.; Nomokonov, V.; Nygren, A.; Obraztsov, V.; Olshevski, A.G.; Onofre, A.; Orava, R.; Orazi, G.; Osterberg, K.; Ouraou, A.; Paganoni, M.; Paiano, S.; Pain, R.; Paiva, R.; Palacios, J.; Palka, H.; Papadopoulou, T.D.; Pape, L.; Parkes, C.; Parodi, F.; Parzefall, U.; Passeri, A.; Passon, O.; Pavel, T.; Pegoraro, M.; Peralta, L.; Pernicka, M.; Perrotta, A.; Petridou, C.; Petrolini, A.; Phillips, H.T.; Pierre, F.; Pimenta, M.; Piotto, E.; Podobnik, T.; Pol, M.E.; Polok, G.; Poropat, P.; Pozdniakov, V.; Privitera, P.; Pukhaeva, N.; Pullia, A.; Radojicic, D.; Ragazzi, S.; Rahmani, H.; Rames, J.; Ratoff, P.N.; Read, Alexander L.; Rebecchi, P.; Redaelli, Nicola Giuseppe; Regler, M.; Rehn, J.; Reid, D.; Reinhardt, R.; Renton, P.B.; Resvanis, L.K.; Richard, F.; Ridky, J.; Rinaudo, G.; Ripp-Baudot, Isabelle; Rohne, O.; Romero, A.; Ronchese, P.; Rosenberg, E.I.; Rosinsky, P.; Roudeau, P.; Rovelli, T.; Royon, C.; Ruhlmann-Kleider, V.; Ruiz, A.; Saarikko, H.; Sacquin, Y.; Sadovsky, A.; Sajot, G.; Salt, J.; Sampsonidis, D.; Sannino, M.; Schwemling, P.; Schwering, B.; Schwickerath, U.; Scuri, Fabrizio; Seager, P.; Sedykh, Y.; Segar, A.M.; Seibert, N.; Sekulin, R.; Shellard, R.C.; Siebel, M.; Simard, L.; Simonetto, F.; Sisakian, A.N.; Smadja, G.; Smirnova, O.; Smith, G.R.; Solovianov, O.; Sopczak, A.; Sosnowski, R.; Spassov, T.; Spiriti, E.; Squarcia, S.; Stanescu, C.; Stanic, S.; Stanitzki, M.; Stevenson, K.; Stocchi, A.; Strauss, J.; Strub, R.; Stugu, B.; Szczekowski, M.; Szeptycka, M.; Tabarelli, T.; Taffard, A.; Tegenfeldt, F.; Terranova, F.; Thomas, J.; Timmermans, Jan; Tinti, N.; Tkatchev, L.G.; Tobin, M.; Todorova, S.; Tomaradze, A.; Tome, B.; Tonazzo, A.; Tortora, L.; Tortosa, P.; Transtromer, G.; Treille, D.; Tristram, G.; Trochimczuk, M.; Troncon, C.; Turluer, M.L.; Tyapkin, I.A.; Tyapkin, P.; Tzamarias, S.; Ullaland, O.; Uvarov, V.; Valenti, G.; Vallazza, E.; Van Dam, Piet; Van den Boeck, W.; Van Doninck, Walter; Van Eldik, J.; Van Lysebetten, A.; van Remortel, N.; Van Vulpen, I.; Vegni, G.; Ventura, L.; Venus, W.; Verbeure, F.; Verdier, P.; Verlato, M.; Vertogradov, L.S.; Verzi, V.; Vilanova, D.; Vitale, L.; Vlasov, E.; Vodopianov, A.S.; Voulgaris, G.; Vrba, V.; Wahlen, H.; Walck, C.; Washbrook, A.J.; Weiser, C.; Wicke, D.; Wickens, J.H.; Wilkinson, G.R.; Winter, M.; Witek, M.; Wolf, G.; Yi, J.; Yushchenko, O.; Zalewska, A.; Zalewski, P.; Zavrtanik, D.; Zevgolatakos, E.; Zimine, N.I.; Zintchenko, A.; Zoller, P.; Zucchelli, G.C.; Zumerle, G.

    2000-01-01

    A search for stable and long-lived heavy charged particles was performed using the data taken by the DELPHI experiment at an energy of 189 GeV. The Cherenkov light detected in the Ring Imaging Cherenkov Detectorand the ionisation loss measured in the Time Projection Chamber were used to identify heavy particles passing through the detector. No evidence for the production of such particles has been found, therefore exclusion limits at 95% confidence level were derived on the masses of left and right handed smuons and staus. The results were combined with previous DELPHI searches in this channel.Including previous DELPHI re-020

  2. Radiation induced muscositis as space flight risk. Model studies on X-ray and heavy ion irradiated typical oral mucosa models; Strahlungsinduzierte Mukositis als Risiko der Raumfahrt. Modelluntersuchungen an Roentgen- und Schwerionen-bestrahlten organotypischen Mundschleimhaut-Modellen

    Energy Technology Data Exchange (ETDEWEB)

    Tschachojan, Viktoria

    2014-07-29

    Humans in exomagnetospheric space are exposed to highly energetic heavy ion radiation which can be hardly shielded. Since radiation-induced mucositis constitutes a severe complication of heavy ion radiotherapy, it would also implicate a serious medical safety risk for the crew members during prolonged space flights such as missions to Moon or Mars. For assessment of risk developing radiation-induced mucositis, three-dimensional organotypic cultures of immortalized human keratinocytes and fibroblasts were irradiated with a {sup 12}C particle beam at high energies or X-Rays. Immunofluorescence stainings were done from cryosections and radiation induced release of cytokines and chemokines was quantified by ELISA from culture supernatants. The major focuses of this study were on 4, 8, 24 and 48 hours after irradiation. The conducted analyses of our mucosa model showed many structural similarities with the native oral mucosa and authentic immunological responses to radiation exposure. Quantification of the DNA damage in irradiated mucosa models revealed about twice as many DSB after heavy-ion irradiation compared to X-rays at definite doses and time points, suggesting a higher gene toxicity of heavy ions. Nuclear factor κB activation was observed after treatment with X-rays or {sup 12}C particles. An activation of NF κB p65 in irradiated samples could not be detected. ELISA analyses showed significantly higher interleukin 6 and interleukin 8 levels after irradiation with X-rays and {sup 12}C particles compared to non-irradiated controls. However, only X-rays induced significantly higher levels of interleukin 1β. Analyses of TNF-α and IFN-γ showed no radiation-induced effects. Further analyses revealed a radiation-induced reduction in proliferation and loss of compactness in irradiated oral mucosa model, which would lead to local lesions in vivo. In this study we revealed that several pro-inflammatory markers and structural changes are induced by X-rays and heavy

  3. Measuring Density Profiles of Electrons and Heavy Particles in a Stable Axially Blown Arc

    Science.gov (United States)

    Carstensen, J.; Stoller, P.; Galletti, B.; Doiron, C. B.; Sokolov, A.

    2017-08-01

    Two-color spatial carrier wave interferometry employing pulsed 532- and 671-nm lasers is used to measure the electron-density and heavy-particle-density profiles in the stagnation point of a stable, axially blown arc in argon for currents of 50 to 200 A and stagnation point pressures of 0.2 to 16 bar. This technique takes advantage of the fact that the free-electron contribution to the refractive index depends strongly on the wavelength, while that of the heavy particles does not. The high spatial resolution achieved allows the hot core of the arc to be readily distinguished from the surrounding boundary layer. A custom-built test device is used to ensure flow conditions that lead to a stable, axisymmetric arc; this permits the reconstruction of the density and temperature profiles using a single projection (interferometric image) of the refractive-index distribution through the arc (at two wavelengths). The arc radius determined from the heavy-particle density decreases with increasing stagnation pressure and increases with the current. These measurements are in good agreement with a simple axially blown arc model taking into account Ohmic heating, radiation losses, and enthalpy flow for core temperatures of approximately 16 500 K. The measured electron density at the center of the arc agrees well with a prediction based on local thermodynamic equilibrium.

  4. Electron emission from solids induced by swift heavy ions

    International Nuclear Information System (INIS)

    Xiao Guoqing

    2000-01-01

    The recent progresses in experimental and theoretical studies of the collision between swift heavy ion and solids as well as electron emission induced by swift heavy ion in solids were briefly reviewed. Three models, Coulomb explosion, thermal spike and repulsive long-lived states, for interpreting the atomic displacements stimulated by the electronic energy loss were discussed. The experimental setup and methods for measuring the electron emission from solids were described. The signification deviation from a proportionality between total electron emission yields and electronic stopping power was found. Auger-electron and convoy-electron spectra are thought to be a probe for investigating the microscopic production mechanisms of the electronic irradiation-damage. Electron temperature and track potential at the center of nuclear tracks in C and polypropylene foils induced by 5 MeV/u heavy ions, which are related to the electronic excitation density in metals and insulators respectively, were extracted by measuring the high resolution electron spectra

  5. Cataractogenic effects of heavy charged particles in mice

    International Nuclear Information System (INIS)

    Ainsworth, E.J.; Jose, J.G.; Yang, V.V.; Barker, M.E.

    1980-01-01

    The effects of heavy charged particles on the crystalline lens of the eye of mice are important because this tissue has proven susceptible to other forms of high-LET radiation. This report summarizes the results currently available from a prospectively designed study to explore the LET dependence of the cataractogenic process. The present results are consistent with a high cataractogenic effect at 100 keV/μm, because plateau argon 40 ions, with an LET in this range, produce higher average cataracts scores at 9, 11 and 13 months than do carbon 12 or neon 20 ions. In the electron micrographs, significant changes were observed from the controls

  6. Recent heavy particle decay in a matter dominated universe

    Science.gov (United States)

    Olive, K. A.; Seckel, D.; Vishniac, E.

    1984-09-01

    The cold matter scenario for galaxy formation solves the dark matter problem very nicely on small scales corresponding to galaxies and clusters of galaxies. It is, however, difficult to reconcile with a Universe with an Einstein-deSitter value of (UC OMEGA) = 1. Cold matter and (UC OMEGA) = 1 can be made compatible while retaining the feature that the Universe is matter dominated today. This is done by means of heavy (cold) particles whose decay subsequently leads to the unbinding of a large fraction of lighter clustered matter.

  7. Recent heavy-particle decay in a matter-dominated universe

    Energy Technology Data Exchange (ETDEWEB)

    Olive, K.A.; Seckel, D.; Vishniac, E.

    1985-05-01

    The cold-matter scenario for galaxy formation solves the dark-matter problem very nicely on small scales corresponding to galaxies and clusters of galaxies. It is, however, difficult to reconcile with a universe with an Einstein-deSitter value of ..cap omega.. = 1. We will show here that cold matter and ..cap omega.. = 1 can be made compatible while retaining the feature that the universe is matter-dominated today. This is done by means of heavy (cold) particles whose decay subsequently leads to the unbinding of a large fraction of lighter clustered matter.

  8. Recent heavy particle decay in a matter dominated universe

    International Nuclear Information System (INIS)

    Olive, K.A.; Seckel, D.; Vishniac, E.

    1984-09-01

    The cold matter scenario for galaxy formation solves the dark matter problem very nicely on small scales corresponding to galaxies and clusters of galaxies. It is, however, difficult to reconcile with a Universe with an Einstein-deSitter value of Ω = 1. We will show here that cold matter and Ω = 1 can be made compatible while retaining the feature that the Universe is matter dominated today. This is done by means of heavy (cold) particles whose decay subsequently leads to the unbinding of a large fraction of lighter clustered matter. 33 references

  9. Recent heavy-particle decay in a matter-dominated universe

    International Nuclear Information System (INIS)

    Olive, K.A.; Seckel, D.; Vishniac, E.

    1985-01-01

    The cold-matter scenario for galaxy formation solves the dark-matter problem very nicely on small scales corresponding to galaxies and clusters of galaxies. It is, however, difficult to reconcile with a universe with an Einstein-deSitter value of Ω = 1. We will show here that cold matter and Ω = 1 can be made compatible while retaining the feature that the universe is matter-dominated today. This is done by means of heavy (cold) particles whose decay subsequently leads to the unbinding of a large fraction of lighter clustered matter

  10. Recent heavy-particle decay in a matter-dominated universe

    Science.gov (United States)

    Olive, K. A.; Seckel, D.; Vishniac, E.

    1985-05-01

    The cold-matter scenario for galaxy formation solves the dark-matter problem very nicely on small scales corresponding to galaxies and clusters of galaxies. It is, however, difficult to reconcile with a universe with an Einstein-deSitter value of Ω = 1. It is shown here that cold matter and Ω = 1 can be made compatible while retaining the feature that the universe is matter-dominated today. This is done by means of heavy (cold) particles whose decay subsequently leads to the unbinding of a large fraction of lighter clustered matter.

  11. Recent heavy particle decay in a matter dominated universe

    Energy Technology Data Exchange (ETDEWEB)

    Olive, K.A.; Seckel, D.; Vishniac, E.

    1984-09-01

    The cold matter scenario for galaxy formation solves the dark matter problem very nicely on small scales corresponding to galaxies and clusters of galaxies. It is, however, difficult to reconcile with a Universe with an Einstein-deSitter value of ..cap omega.. = 1. We will show here that cold matter and ..cap omega.. = 1 can be made compatible while retaining the feature that the Universe is matter dominated today. This is done by means of heavy (cold) particles whose decay subsequently leads to the unbinding of a large fraction of lighter clustered matter. 33 references.

  12. Search for Heavy Stable Charged Particles in pp collisions at $\\sqrt{s}$ = 7 TeV

    CERN Document Server

    Khachatryan, Vardan; Tumasyan, Armen; Adam, Wolfgang; Bergauer, Thomas; Dragicevic, Marko; Erö, Janos; Fabjan, Christian; Friedl, Markus; Fruehwirth, Rudolf; Ghete, Vasile Mihai; Hammer, Josef; Haensel, Stephan; Hartl, Christian; Hoch, Michael; Hörmann, Natascha; Hrubec, Josef; Jeitler, Manfred; Kasieczka, Gregor; Kiesenhofer, Wolfgang; Krammer, Manfred; Liko, Dietrich; Mikulec, Ivan; Pernicka, Manfred; Rohringer, Herbert; Schöfbeck, Robert; Strauss, Josef; Taurok, Anton; Teischinger, Florian; Waltenberger, Wolfgang; Walzel, Gerhard; Widl, Edmund; Wulz, Claudia-Elisabeth; Mossolov, Vladimir; Shumeiko, Nikolai; Suarez Gonzalez, Juan; Benucci, Leonardo; Ceard, Ludivine; Cerny, Karel; De Wolf, Eddi A.; Janssen, Xavier; Maes, Thomas; Mucibello, Luca; Ochesanu, Silvia; Roland, Benoit; Rougny, Romain; Selvaggi, Michele; Van Haevermaet, Hans; Van Mechelen, Pierre; Van Remortel, Nick; Adler, Volker; Beauceron, Stephanie; Blekman, Freya; Blyweert, Stijn; D'Hondt, Jorgen; Devroede, Olivier; Gonzalez Suarez, Rebeca; Kalogeropoulos, Alexis; Maes, Joris; Maes, Michael; Tavernier, Stefaan; Van Doninck, Walter; Van Mulders, Petra; Van Onsem, Gerrit Patrick; Villella, Ilaria; Charaf, Otman; Clerbaux, Barbara; De Lentdecker, Gilles; Dero, Vincent; Gay, Arnaud; Hammad, Gregory Habib; Hreus, Tomas; Marage, Pierre Edouard; Thomas, Laurent; Vander Velde, Catherine; Vanlaer, Pascal; Wickens, John; Costantini, Silvia; Grunewald, Martin; Klein, Benjamin; Marinov, Andrey; Mccartin, Joseph; Ryckbosch, Dirk; Thyssen, Filip; Tytgat, Michael; Vanelderen, Lukas; Verwilligen, Piet; Walsh, Sinead; Zaganidis, Nicolas; Basegmez, Suzan; Bruno, Giacomo; Caudron, Julien; De Favereau De Jeneret, Jerome; Delaere, Christophe; Demin, Pavel; Favart, Denis; Giammanco, Andrea; Grégoire, Ghislain; Hollar, Jonathan; Lemaitre, Vincent; Liao, Junhui; Militaru, Otilia; Ovyn, Severine; Pagano, Davide; Pin, Arnaud; Piotrzkowski, Krzysztof; Quertenmont, Loic; Schul, Nicolas; Beliy, Nikita; Caebergs, Thierry; Daubie, Evelyne; Alves, Gilvan; De Jesus Damiao, Dilson; Pol, Maria Elena; Henrique Gomes E Souza, Moacyr; Carvalho, Wagner; Melo Da Costa, Eliza; De Oliveira Martins, Carley; Fonseca De Souza, Sandro; Mundim, Luiz; Nogima, Helio; Oguri, Vitor; Prado Da Silva, Wanda Lucia; Santoro, Alberto; Silva Do Amaral, Sheila Mara; Sznajder, Andre; De Almeida Dias, Flavia; Ferreira Dias, Marco Andre; Tomei, Thiago; De Moraes Gregores, Eduardo; Da Cunha Marinho, Franciole; Novaes, Sergio F.; Padula, Sandra; Darmenov, Nikolay; Dimitrov, Lubomir; Genchev, Vladimir; Iaydjiev, Plamen; Piperov, Stefan; Rodozov, Mircho; Stoykova, Stefka; Sultanov, Georgi; Tcholakov, Vanio; Trayanov, Rumen; Vankov, Ivan; Dyulendarova, Milena; Hadjiiska, Roumyana; Kozhuharov, Venelin; Litov, Leander; Marinova, Evelina; Mateev, Matey; Pavlov, Borislav; Petkov, Peicho; Bian, Jian-Guo; Chen, Guo-Ming; Chen, He-Sheng; Jiang, Chun-Hua; Liang, Dong; Liang, Song; Wang, Jian; Wang, Jian; Wang, Xianyou; Wang, Zheng; Xu, Ming; Yang, Min; Zang, Jingjing; Zhang, Zhen; Ban, Yong; Guo, Shuang; Li, Wenbo; Mao, Yajun; Qian, Si-Jin; Teng, Haiyun; Zhang, Linlin; Zhu, Bo; Cabrera, Andrés; Gomez Moreno, Bernardo; Ocampo Rios, Alberto Andres; Osorio Oliveros, Andres Felipe; Sanabria, Juan Carlos; Godinovic, Nikola; Lelas, Damir; Lelas, Karlo; Plestina, Roko; Polic, Dunja; Puljak, Ivica; Antunovic, Zeljko; Dzelalija, Mile; Brigljevic, Vuko; Duric, Senka; Kadija, Kreso; Morovic, Srecko; Attikis, Alexandros; Galanti, Mario; Mousa, Jehad; Nicolaou, Charalambos; Ptochos, Fotios; Razis, Panos A.; Rykaczewski, Hans; Assran, Yasser; Mahmoud, Mohammed; Hektor, Andi; Kadastik, Mario; Kannike, Kristjan; Müntel, Mait; Raidal, Martti; Rebane, Liis; Azzolini, Virginia; Eerola, Paula; Czellar, Sandor; Härkönen, Jaakko; Heikkinen, Mika Aatos; Karimäki, Veikko; Kinnunen, Ritva; Klem, Jukka; Kortelainen, Matti J.; Lampén, Tapio; Lassila-Perini, Kati; Lehti, Sami; Lindén, Tomas; Luukka, Panja-Riina; Mäenpää, Teppo; Tuominen, Eija; Tuominiemi, Jorma; Tuovinen, Esa; Ungaro, Donatella; Wendland, Lauri; Banzuzi, Kukka; Korpela, Arja; Tuuva, Tuure; Sillou, Daniel; Besancon, Marc; Choudhury, Somnath; Dejardin, Marc; Denegri, Daniel; Fabbro, Bernard; Faure, Jean-Louis; Ferri, Federico; Ganjour, Serguei; Gentit, François-Xavier; Givernaud, Alain; Gras, Philippe; Hamel de Monchenault, Gautier; Jarry, Patrick; Locci, Elizabeth; Malcles, Julie; Marionneau, Matthieu; Millischer, Laurent; Rander, John; Rosowsky, André; Shreyber, Irina; Titov, Maksym; Verrecchia, Patrice; Baffioni, Stephanie; Beaudette, Florian; Bianchini, Lorenzo; Bluj, Michal; Broutin, Clementine; Busson, Philippe; Charlot, Claude; Dahms, Torsten; Dobrzynski, Ludwik; Granier de Cassagnac, Raphael; Haguenauer, Maurice; Miné, Philippe; Mironov, Camelia; Ochando, Christophe; Paganini, Pascal; Sabes, David; Salerno, Roberto; Sirois, Yves; Thiebaux, Christophe; Wyslouch, Bolek; Zabi, Alexandre; Agram, Jean-Laurent; Andrea, Jeremy; Besson, Auguste; Bloch, Daniel; Bodin, David; Brom, Jean-Marie; Cardaci, Marco; Chabert, Eric Christian; Collard, Caroline; Conte, Eric; Drouhin, Frédéric; Ferro, Cristina; Fontaine, Jean-Charles; Gelé, Denis; Goerlach, Ulrich; Greder, Sebastien; Juillot, Pierre; Karim, Mehdi; Le Bihan, Anne-Catherine; Mikami, Yoshinari; Van Hove, Pierre; Fassi, Farida; Mercier, Damien; Baty, Clement; Beaupere, Nicolas; Bedjidian, Marc; Bondu, Olivier; Boudoul, Gaelle; Boumediene, Djamel; Brun, Hugues; Chanon, Nicolas; Chierici, Roberto; Contardo, Didier; Depasse, Pierre; El Mamouni, Houmani; Falkiewicz, Anna; Fay, Jean; Gascon, Susan; Ille, Bernard; Kurca, Tibor; Le Grand, Thomas; Lethuillier, Morgan; Mirabito, Laurent; Perries, Stephane; Sordini, Viola; Tosi, Silvano; Tschudi, Yohann; Verdier, Patrice; Xiao, Hong; Roinishvili, Vladimir; Anagnostou, Georgios; Edelhoff, Matthias; Feld, Lutz; Heracleous, Natalie; Hindrichs, Otto; Jussen, Ruediger; Klein, Katja; Merz, Jennifer; Mohr, Niklas; Ostapchuk, Andrey; Perieanu, Adrian; Raupach, Frank; Sammet, Jan; Schael, Stefan; Sprenger, Daniel; Weber, Hendrik; Weber, Martin; Wittmer, Bruno; Ata, Metin; Bender, Walter; Erdmann, Martin; Frangenheim, Jens; Hebbeker, Thomas; Hinzmann, Andreas; Hoepfner, Kerstin; Hof, Carsten; Klimkovich, Tatsiana; Klingebiel, Dennis; Kreuzer, Peter; Lanske, Dankfried; Magass, Carsten; Masetti, Gianni; Merschmeyer, Markus; Meyer, Arnd; Papacz, Paul; Pieta, Holger; Reithler, Hans; Schmitz, Stefan Antonius; Sonnenschein, Lars; Steggemann, Jan; Teyssier, Daniel; Bontenackels, Michael; Davids, Martina; Duda, Markus; Flügge, Günter; Geenen, Heiko; Giffels, Manuel; Haj Ahmad, Wael; Heydhausen, Dirk; Kress, Thomas; Kuessel, Yvonne; Linn, Alexander; Nowack, Andreas; Perchalla, Lars; Pooth, Oliver; Rennefeld, Jörg; Sauerland, Philip; Stahl, Achim; Thomas, Maarten; Tornier, Daiske; Zoeller, Marc Henning; Aldaya Martin, Maria; Behrenhoff, Wolf; Behrens, Ulf; Bergholz, Matthias; Borras, Kerstin; Cakir, Altan; Campbell, Alan; Castro, Elena; Dammann, Dirk; Eckerlin, Guenter; Eckstein, Doris; Flossdorf, Alexander; Flucke, Gero; Geiser, Achim; Glushkov, Ivan; Hauk, Johannes; Jung, Hannes; Kasemann, Matthias; Katkov, Igor; Katsas, Panagiotis; Kleinwort, Claus; Kluge, Hannelies; Knutsson, Albert; Krücker, Dirk; Kuznetsova, Ekaterina; Lange, Wolfgang; Lohmann, Wolfgang; Mankel, Rainer; Marienfeld, Markus; Melzer-Pellmann, Isabell-Alissandra; Meyer, Andreas Bernhard; Mnich, Joachim; Mussgiller, Andreas; Olzem, Jan; Parenti, Andrea; Raspereza, Alexei; Raval, Amita; Schmidt, Ringo; Schoerner-Sadenius, Thomas; Sen, Niladri; Stein, Matthias; Tomaszewska, Justyna; Volyanskyy, Dmytro; Walsh, Roberval; Wissing, Christoph; Autermann, Christian; Bobrovskyi, Sergei; Draeger, Jula; Enderle, Holger; Gebbert, Ulla; Kaschube, Kolja; Kaussen, Gordon; Klanner, Robert; Lange, Jörn; Mura, Benedikt; Naumann-Emme, Sebastian; Nowak, Friederike; Pietsch, Niklas; Sander, Christian; Schettler, Hannes; Schleper, Peter; Schröder, Matthias; Schum, Torben; Schwandt, Joern; Srivastava, Ajay Kumar; Stadie, Hartmut; Steinbrück, Georg; Thomsen, Jan; Wolf, Roger; Barth, Christian; Bauer, Julia; Buege, Volker; Chwalek, Thorsten; De Boer, Wim; Dierlamm, Alexander; Dirkes, Guido; Feindt, Michael; Gruschke, Jasmin; Hackstein, Christoph; Hartmann, Frank; Heindl, Stefan Michael; Heinrich, Michael; Held, Hauke; Hoffmann, Karl-Heinz; Honc, Simon; Kuhr, Thomas; Martschei, Daniel; Mueller, Steffen; Müller, Thomas; Niegel, Martin; Oberst, Oliver; Oehler, Andreas; Ott, Jochen; Peiffer, Thomas; Piparo, Danilo; Quast, Gunter; Rabbertz, Klaus; Ratnikov, Fedor; Renz, Manuel; Saout, Christophe; Scheurer, Armin; Schieferdecker, Philipp; Schilling, Frank-Peter; Schott, Gregory; Simonis, Hans-Jürgen; Stober, Fred-Markus Helmut; Troendle, Daniel; Wagner-Kuhr, Jeannine; Zeise, Manuel; Zhukov, Valery; Ziebarth, Eva Barbara; Daskalakis, Georgios; Geralis, Theodoros; Kesisoglou, Stilianos; Kyriakis, Aristotelis; Loukas, Demetrios; Manolakos, Ioannis; Markou, Athanasios; Markou, Christos; Mavrommatis, Charalampos; Petrakou, Eleni; Gouskos, Loukas; Mertzimekis, Theodoros; Panagiotou, Apostolos; Evangelou, Ioannis; Foudas, Costas; Kokkas, Panagiotis; Manthos, Nikolaos; Papadopoulos, Ioannis; Patras, Vaios; Triantis, Frixos A.; Aranyi, Attila; Bencze, Gyorgy; Boldizsar, Laszlo; Debreczeni, Gergely; Hajdu, Csaba; Horvath, Dezso; Kapusi, Anita; Krajczar, Krisztian; Laszlo, Andras; Sikler, Ferenc; Vesztergombi, Gyorgy; Beni, Noemi; Molnar, Jozsef; Palinkas, Jozsef; Szillasi, Zoltan; Veszpremi, Viktor; Raics, Peter; Trocsanyi, Zoltan Laszlo; Ujvari, Balazs; Bansal, Sunil; Beri, Suman Bala; Bhatnagar, Vipin; Dhingra, Nitish; Jindal, Monika; Kaur, Manjit; Kohli, Jatinder Mohan; Mehta, Manuk Zubin; Nishu, Nishu; Saini, Lovedeep Kaur; Sharma, Archana; Singh, Anil; Singh, Jas Bir; Singh, Supreet Pal; Ahuja, Sudha; Bhattacharya, Satyaki; Choudhary, Brajesh C.; Gupta, Pooja; Jain, Sandhya; Jain, Shilpi; Kumar, Ashok; Shivpuri, Ram Krishen; Choudhury, Rajani Kant; Dutta, Dipanwita; Kailas, Swaminathan; Kataria, Sushil Kumar; Mohanty, Ajit Kumar; Pant, Lalit Mohan; Shukla, Prashant; Aziz, Tariq; Guchait, Monoranjan; Gurtu, Atul; Maity, Manas; Majumder, Devdatta; Majumder, Gobinda; Mazumdar, Kajari; Mohanty, Gagan Bihari; Saha, Anirban; Sudhakar, Katta; Wickramage, Nadeesha; Banerjee, Sudeshna; Dugad, Shashikant; Mondal, Naba Kumar; Arfaei, Hessamaddin; Bakhshiansohi, Hamed; Etesami, Seyed Mohsen; Fahim, Ali; Hashemi, Majid; Jafari, Abideh; Khakzad, Mohsen; Mohammadi, Abdollah; Mohammadi Najafabadi, Mojtaba; Paktinat Mehdiabadi, Saeid; Safarzadeh, Batool; Zeinali, Maryam; Abbrescia, Marcello; Barbone, Lucia; Calabria, Cesare; Colaleo, Anna; Creanza, Donato; De Filippis, Nicola; De Palma, Mauro; Dimitrov, Anton; Fiore, Luigi; Iaselli, Giuseppe; Lusito, Letizia; Maggi, Giorgio; Maggi, Marcello; Manna, Norman; Marangelli, Bartolomeo; My, Salvatore; Nuzzo, Salvatore; Pacifico, Nicola; Pierro, Giuseppe Antonio; Pompili, Alexis; Pugliese, Gabriella; Romano, Francesco; Roselli, Giuseppe; Selvaggi, Giovanna; Silvestris, Lucia; Trentadue, Raffaello; Tupputi, Salvatore; Zito, Giuseppe; Abbiendi, Giovanni; Benvenuti, Alberto; Bonacorsi, Daniele; Braibant-Giacomelli, Sylvie; Brigliadori, Luca; Capiluppi, Paolo; Castro, Andrea; Cavallo, Francesca Romana; Cuffiani, Marco; Dallavalle, Gaetano-Marco; Fabbri, Fabrizio; Fanfani, Alessandra; Fasanella, Daniele; Giacomelli, Paolo; Giunta, Marina; Marcellini, Stefano; Meneghelli, Marco; Montanari, Alessandro; Navarria, Francesco; Odorici, Fabrizio; Perrotta, Andrea; Primavera, Federica; Rossi, Antonio; Rovelli, Tiziano; Siroli, Gianni; Travaglini, Riccardo; Albergo, Sebastiano; Cappello, Gigi; Chiorboli, Massimiliano; Costa, Salvatore; Tricomi, Alessia; Tuve, Cristina; Barbagli, Giuseppe; Ciulli, Vitaliano; Civinini, Carlo; D'Alessandro, Raffaello; Focardi, Ettore; Frosali, Simone; Gallo, Elisabetta; Genta, Chiara; Lenzi, Piergiulio; Meschini, Marco; Paoletti, Simone; Sguazzoni, Giacomo; Tropiano, Antonio; Benussi, Luigi; Bianco, Stefano; Colafranceschi, Stefano; Fabbri, Franco; Piccolo, Davide; Fabbricatore, Pasquale; Musenich, Riccardo; Benaglia, Andrea; De Guio, Federico; Di Matteo, Leonardo; Ghezzi, Alessio; Malberti, Martina; Malvezzi, Sandra; Martelli, Arabella; Massironi, Andrea; Menasce, Dario; Moroni, Luigi; Paganoni, Marco; Pedrini, Daniele; Ragazzi, Stefano; Redaelli, Nicola; Sala, Silvano; Tabarelli de Fatis, Tommaso; Tancini, Valentina; Buontempo, Salvatore; Carrillo Montoya, Camilo Andres; Cimmino, Anna; De Cosa, Annapaola; De Gruttola, Michele; Fabozzi, Francesco; Iorio, Alberto Orso Maria; Lista, Luca; Merola, Mario; Noli, Pasquale; Paolucci, Pierluigi; Azzi, Patrizia; Bacchetta, Nicola; Bellan, Paolo; Bisello, Dario; Branca, Antonio; Carlin, Roberto; Conti, Enrico; De Mattia, Marco; Dorigo, Tommaso; Fanzago, Federica; Gasparini, Fabrizio; Giubilato, Piero; Gonella, Franco; Gresele, Ambra; Lacaprara, Stefano; Lazzizzera, Ignazio; Margoni, Martino; Mazzucato, Mirco; Meneguzzo, Anna Teresa; Nespolo, Massimo; Pegoraro, Matteo; Perrozzi, Luca; Pozzobon, Nicola; Ronchese, Paolo; Torassa, Ezio; Tosi, Mia; Triossi, Andrea; Vanini, Sara; Ventura, Sandro; Zumerle, Gianni; Baesso, Paolo; Berzano, Umberto; Riccardi, Cristina; Torre, Paola; Vitulo, Paolo; Viviani, Claudio; Biasini, Maurizio; Bilei, Gian Mario; Caponeri, Benedetta; Fanò, Livio; Lariccia, Paolo; Lucaroni, Andrea; Mantovani, Giancarlo; Menichelli, Mauro; Nappi, Aniello; Santocchia, Attilio; Servoli, Leonello; Taroni, Silvia; Valdata, Marisa; Volpe, Roberta; Azzurri, Paolo; Bagliesi, Giuseppe; Bernardini, Jacopo; Boccali, Tommaso; Broccolo, Giuseppe; Castaldi, Rino; D'Agnolo, Raffaele Tito; Dell'Orso, Roberto; Fiori, Francesco; Foà, Lorenzo; Giassi, Alessandro; Kraan, Aafke; Ligabue, Franco; Lomtadze, Teimuraz; Martini, Luca; Messineo, Alberto; Palla, Fabrizio; Palmonari, Francesco; Sarkar, Subir; Segneri, Gabriele; Serban, Alin Titus; Spagnolo, Paolo; Tenchini, Roberto; Tonelli, Guido; Venturi, Andrea; Verdini, Piero Giorgio; Barone, Luciano; Cavallari, Francesca; Del Re, Daniele; Di Marco, Emanuele; Diemoz, Marcella; Franci, Daniele; Grassi, Marco; Longo, Egidio; Organtini, Giovanni; Palma, Alessandro; Pandolfi, Francesco; Paramatti, Riccardo; Rahatlou, Shahram; Amapane, Nicola; Arcidiacono, Roberta; Argiro, Stefano; Arneodo, Michele; Biino, Cristina; Botta, Cristina; Cartiglia, Nicolo; Castello, Roberto; Costa, Marco; Demaria, Natale; Graziano, Alberto; Mariotti, Chiara; Marone, Matteo; Maselli, Silvia; Migliore, Ernesto; Mila, Giorgia; Monaco, Vincenzo; Musich, Marco; Obertino, Maria Margherita; Pastrone, Nadia; Pelliccioni, Mario; Romero, Alessandra; Ruspa, Marta; Sacchi, Roberto; Sola, Valentina; Solano, Ada; Staiano, Amedeo; Trocino, Daniele; Vilela Pereira, Antonio; Ambroglini, Filippo; Belforte, Stefano; Cossutti, Fabio; Della Ricca, Giuseppe; Gobbo, Benigno; Montanino, Damiana; Penzo, Aldo; Heo, Seong Gu; Chang, Sunghyun; Chung, Jin Hyuk; Kim, Dong Hee; Kim, Gui Nyun; Kim, Ji Eun; Kong, Dae Jung; Park, Hyangkyu; Son, Dohhee; Son, Dong-Chul; Kim, Jaeho; Kim, Jae Yool; Song, Sanghyeon; Choi, Suyong; Hong, Byung-Sik; Jo, Mihee; Kim, Hyunchul; Kim, Ji Hyun; Kim, Tae Jeong; Lee, Kyong Sei; Moon, Dong Ho; Park, Sung Keun; Rhee, Han-Bum; Seo, Eunsung; Shin, Seungsu; Sim, Kwang Souk; Choi, Minkyoo; Kang, Seokon; Kim, Hyunyong; Park, Chawon; Park, Inkyu; Park, Sangnam; Ryu, Geonmo; Choi, Young-Il; Choi, Young Kyu; Goh, Junghwan; Lee, Jongseok; Lee, Sungeun; Seo, Hyunkwan; Yu, Intae; Bilinskas, Mykolas Jurgis; Grigelionis, Ignas; Janulis, Mindaugas; Martisiute, Dalia; Petrov, Pavel; Sabonis, Tomas; Castilla Valdez, Heriberto; De La Cruz Burelo, Eduard; Lopez-Fernandez, Ricardo; Sánchez Hernández, Alberto; Villasenor-Cendejas, Luis Manuel; Carrillo Moreno, Salvador; Vazquez Valencia, Fabiola; Salazar Ibarguen, Humberto Antonio; Casimiro Linares, Edgar; Morelos Pineda, Antonio; Reyes-Santos, Marco A.; Allfrey, Philip; Krofcheck, David; Butler, Philip H.; Doesburg, Robert; Silverwood, Hamish; Ahmad, Muhammad; Ahmed, Ijaz; Asghar, Muhammad Irfan; Hoorani, Hafeez R.; Khan, Wajid Ali; Khurshid, Taimoor; Qazi, Shamona; Cwiok, Mikolaj; Dominik, Wojciech; Doroba, Krzysztof; Kalinowski, Artur; Konecki, Marcin; Krolikowski, Jan; Frueboes, Tomasz; Gokieli, Ryszard; Górski, Maciej; Kazana, Malgorzata; Nawrocki, Krzysztof; Romanowska-Rybinska, Katarzyna; Szleper, Michal; Wrochna, Grzegorz; Zalewski, Piotr; Almeida, Nuno; David Tinoco Mendes, Andre; Faccioli, Pietro; Ferreira Parracho, Pedro Guilherme; Gallinaro, Michele; Sá Martins, Pedro; Musella, Pasquale; Nayak, Aruna; Ribeiro, Pedro Quinaz; Seixas, Joao; Silva, Pedro; Varela, Joao; Wöhri, Hermine Katharina; Belotelov, Ivan; Bunin, Pavel; Finger, Miroslav; Finger Jr., Michael; Golutvin, Igor; Kamenev, Alexey; Karjavin, Vladimir; Kozlov, Guennady; Lanev, Alexander; Moisenz, Petr; Palichik, Vladimir; Perelygin, Victor; Shmatov, Sergey; Smirnov, Vitaly; Volodko, Anton; Zarubin, Anatoli; Bondar, Nikolai; Golovtsov, Victor; Ivanov, Yury; Kim, Victor; Levchenko, Petr; Murzin, Victor; Oreshkin, Vadim; Smirnov, Igor; Sulimov, Valentin; Uvarov, Lev; Vavilov, Sergey; Vorobyev, Alexey; Andreev, Yuri; Gninenko, Sergei; Golubev, Nikolai; Kirsanov, Mikhail; Krasnikov, Nikolai; Matveev, Viktor; Pashenkov, Anatoli; Toropin, Alexander; Troitsky, Sergey; Epshteyn, Vladimir; Gavrilov, Vladimir; Kaftanov, Vitali; Kossov, Mikhail; Krokhotin, Andrey; Lychkovskaya, Natalia; Safronov, Grigory; Semenov, Sergey; Stolin, Viatcheslav; Vlasov, Evgueni; Zhokin, Alexander; Boos, Edouard; Dubinin, Mikhail; Dudko, Lev; Ershov, Alexander; Gribushin, Andrey; Kodolova, Olga; Lokhtin, Igor; Obraztsov, Stepan; Petrushanko, Sergey; Sarycheva, Ludmila; Savrin, Viktor; Snigirev, Alexander; Andreev, Vladimir; Azarkin, Maksim; Dremin, Igor; Kirakosyan, Martin; Rusakov, Sergey V.; Vinogradov, Alexey; Azhgirey, Igor; Bitioukov, Sergei; Grishin, Viatcheslav; Kachanov, Vassili; Konstantinov, Dmitri; Korablev, Andrey; Krychkine, Victor; Petrov, Vladimir; Ryutin, Roman; Slabospitsky, Sergey; Sobol, Andrei; Tourtchanovitch, Leonid; Troshin, Sergey; Tyurin, Nikolay; Uzunian, Andrey; Volkov, Alexey; Adzic, Petar; Djordjevic, Milos; Krpic, Dragomir; Milosevic, Jovan; Aguilar-Benitez, Manuel; Alcaraz Maestre, Juan; Arce, Pedro; Battilana, Carlo; Calvo, Enrique; Cepeda, Maria; Cerrada, Marcos; Colino, Nicanor; De La Cruz, Begona; Diez Pardos, Carmen; Domínguez Vázquez, Daniel; Fernandez Bedoya, Cristina; Fernández Ramos, Juan Pablo; Ferrando, Antonio; Flix, Jose; Fouz, Maria Cruz; Garcia-Abia, Pablo; Gonzalez Lopez, Oscar; Goy Lopez, Silvia; Hernandez, Jose M.; Josa, Maria Isabel; Merino, Gonzalo; Puerta Pelayo, Jesus; Redondo, Ignacio; Romero, Luciano; Santaolalla, Javier; Willmott, Carlos; Albajar, Carmen; Codispoti, Giuseppe; de Trocóniz, Jorge F; Cuevas, Javier; Fernandez Menendez, Javier; Folgueras, Santiago; Gonzalez Caballero, Isidro; Lloret Iglesias, Lara; Vizan Garcia, Jesus Manuel; Brochero Cifuentes, Javier Andres; Cabrillo, Iban Jose; Calderon, Alicia; Chamizo Llatas, Maria; Chuang, Shan-Huei; Duarte Campderros, Jordi; Felcini, Marta; Fernandez, Marcos; Gomez, Gervasio; Gonzalez Sanchez, Javier; Jorda, Clara; Lobelle Pardo, Patricia; Lopez Virto, Amparo; Marco, Jesus; Marco, Rafael; Martinez Rivero, Celso; Matorras, Francisco; Munoz Sanchez, Francisca Javiela; Piedra Gomez, Jonatan; Rodrigo, Teresa; Ruiz Jimeno, Alberto; Scodellaro, Luca; Sobron Sanudo, Mar; Vila, Ivan; Vilar Cortabitarte, Rocio; Abbaneo, Duccio; Auffray, Etiennette; Auzinger, Georg; Baillon, Paul; Ball, Austin; Barney, David; Bell, Alan James; Benedetti, Daniele; Bernet, Colin; Bialas, Wojciech; Bloch, Philippe; Bocci, Andrea; Bolognesi, Sara; Breuker, Horst; Brona, Grzegorz; Bunkowski, Karol; Camporesi, Tiziano; Cano, Eric; Cerminara, Gianluca; Christiansen, Tim; Coarasa Perez, Jose Antonio; Curé, Benoît; D'Enterria, David; De Roeck, Albert; Duarte Ramos, Fernando; Elliott-Peisert, Anna; Frisch, Benjamin; Funk, Wolfgang; Gaddi, Andrea; Gennai, Simone; Georgiou, Georgios; Gerwig, Hubert; Gigi, Dominique; Gill, Karl; Giordano, Domenico; Glege, Frank; Gomez-Reino Garrido, Robert; Gouzevitch, Maxime; Govoni, Pietro; Gowdy, Stephen; Guiducci, Luigi; Hansen, Magnus; Harvey, John; Hegeman, Jeroen; Hegner, Benedikt; Henderson, Conor; Hesketh, Gavin; Hoffmann, Hans Falk; Honma, Alan; Innocente, Vincenzo; Janot, Patrick; Karavakis, Edward; Lecoq, Paul; Leonidopoulos, Christos; Lourenco, Carlos; Macpherson, Alick; Maki, Tuula; Malgeri, Luca; Mannelli, Marcello; Masetti, Lorenzo; Meijers, Frans; Mersi, Stefano; Meschi, Emilio; Moser, Roland; Mozer, Matthias Ulrich; Mulders, Martijn; Nesvold, Erik; Nguyen, Matthew; Orimoto, Toyoko; Orsini, Luciano; Perez, Emmanuelle; Petrilli, Achille; Pfeiffer, Andreas; Pierini, Maurizio; Pimiä, Martti; Polese, Giovanni; Racz, Attila; Rolandi, Gigi; Rommerskirchen, Tanja; Rovelli, Chiara; Rovere, Marco; Sakulin, Hannes; Schäfer, Christoph; Schwick, Christoph; Segoni, Ilaria; Sharma, Archana; Siegrist, Patrice; Simon, Michal; Sphicas, Paraskevas; Spiga, Daniele; Spiropulu, Maria; Stöckli, Fabian; Stoye, Markus; Tropea, Paola; Tsirou, Andromachi; Tsyganov, Andrey; Veres, Gabor Istvan; Vichoudis, Paschalis; Voutilainen, Mikko; Zeuner, Wolfram Dietrich; Bertl, Willi; Deiters, Konrad; Erdmann, Wolfram; Gabathuler, Kurt; Horisberger, Roland; Ingram, Quentin; Kaestli, Hans-Christian; König, Stefan; Kotlinski, Danek; Langenegger, Urs; Meier, Frank; Renker, Dieter; Rohe, Tilman; Sibille, Jennifer; Starodumov, Andrei; Bortignon, Pierluigi; Caminada, Lea; Chen, Zhiling; Cittolin, Sergio; Dissertori, Günther; Dittmar, Michael; Eugster, Jürg; Freudenreich, Klaus; Grab, Christoph; Hervé, Alain; Hintz, Wieland; Lecomte, Pierre; Lustermann, Werner; Marchica, Carmelo; Martinez Ruiz del Arbol, Pablo; Meridiani, Paolo; Milenovic, Predrag; Moortgat, Filip; Nef, Pascal; Nessi-Tedaldi, Francesca; Pape, Luc; Pauss, Felicitas; Punz, Thomas; Rizzi, Andrea; Ronga, Frederic Jean; Rossini, Marco; Sala, Leonardo; Sanchez, Ann - Karin; Sawley, Marie-Christine; Stieger, Benjamin; Tauscher, Ludwig; Thea, Alessandro; Theofilatos, Konstantinos; Treille, Daniel; Urscheler, Christina; Wallny, Rainer; Weber, Matthias; Wehrli, Lukas; Weng, Joanna; Aguiló, Ernest; Amsler, Claude; Chiochia, Vincenzo; De Visscher, Simon; Favaro, Carlotta; Ivova Rikova, Mirena; Millan Mejias, Barbara; Regenfus, Christian; Robmann, Peter; Schmidt, Alexander; Snoek, Hella; Wilke, Lotte; Chang, Yuan-Hann; Chen, Kuan-Hsin; Chen, Wan-Ting; Dutta, Suchandra; Go, Apollo; Kuo, Chia-Ming; Li, Syue-Wei; Lin, Willis; Liu, Ming-Hsiung; Liu, Zong-Kai; Lu, Yun-Ju; Wu, Jing-Han; Yu, Shin-Shan; Bartalini, Paolo; Chang, Paoti; Chang, You-Hao; Chang, Yu-Wei; Chao, Yuan; Chen, Kai-Feng; Hou, George Wei-Shu; Hsiung, Yee; Kao, Kai-Yi; Lei, Yeong-Jyi; Lu, Rong-Shyang; Shiu, Jing-Ge; Tzeng, Yeng-Ming; Wang, Minzu; Adiguzel, Aytul; Bakirci, Mustafa Numan; Cerci, Salim; Dozen, Candan; Dumanoglu, Isa; Eskut, Eda; Girgis, Semiray; Gokbulut, Gul; Guler, Yalcin; Gurpinar, Emine; Hos, Ilknur; Kangal, Evrim Ersin; Karaman, Turker; Kayis Topaksu, Aysel; Nart, Alisah; Onengut, Gulsen; Ozdemir, Kadri; Ozturk, Sertac; Polatoz, Ayse; Sogut, Kenan; Tali, Bayram; Topakli, Huseyin; Uzun, Dilber; Vergili, Latife Nukhet; Vergili, Mehmet; Zorbilmez, Caglar; Akin, Ilina Vasileva; Aliev, Takhmasib; Bilmis, Selcuk; Deniz, Muhammed; Gamsizkan, Halil; Guler, Ali Murat; Ocalan, Kadir; Ozpineci, Altug; Serin, Meltem; Sever, Ramazan; Surat, Ugur Emrah; Yildirim, Eda; Zeyrek, Mehmet; Deliomeroglu, Mehmet; Demir, Durmus; Gülmez, Erhan; Halu, Arda; Isildak, Bora; Kaya, Mithat; Kaya, Ozlem; Ozkorucuklu, Suat; Sonmez, Nasuf; Levchuk, Leonid; Bell, Peter; Bostock, Francis; Brooke, James John; Cheng, Teh Lee; Clement, Emyr; Cussans, David; Frazier, Robert; Goldstein, Joel; Grimes, Mark; Hansen, Maria; Hartley, Dominic; Heath, Greg P.; Heath, Helen F.; Huckvale, Benedickt; Jackson, James; Kreczko, Lukasz; Metson, Simon; Newbold, Dave M.; Nirunpong, Kachanon; Poll, Anthony; Senkin, Sergey; Smith, Vincent J.; Ward, Simon; Basso, Lorenzo; Bell, Ken W.; Belyaev, Alexander; Brew, Christopher; Brown, Robert M.; Camanzi, Barbara; Cockerill, David J.A.; Coughlan, John A.; Harder, Kristian; Harper, Sam; Kennedy, Bruce W.; Olaiya, Emmanuel; Petyt, David; Radburn-Smith, Benjamin Charles; Shepherd-Themistocleous, Claire; Tomalin, Ian R.; Womersley, William John; Worm, Steven; Bainbridge, Robert; Ball, Gordon; Ballin, Jamie; Beuselinck, Raymond; Buchmuller, Oliver; Colling, David; Cripps, Nicholas; Cutajar, Michael; Davies, Gavin; Della Negra, Michel; Fulcher, Jonathan; Futyan, David; Guneratne Bryer, Arlo; Hall, Geoffrey; Hatherell, Zoe; Hays, Jonathan; Iles, Gregory; Karapostoli, Georgia; Lyons, Louis; Magnan, Anne-Marie; Marrouche, Jad; Nandi, Robin; Nash, Jordan; Nikitenko, Alexander; Papageorgiou, Anastasios; Pesaresi, Mark; Petridis, Konstantinos; Pioppi, Michele; Raymond, David Mark; Rompotis, Nikolaos; Rose, Andrew; Ryan, Matthew John; Seez, Christopher; Sharp, Peter; Sparrow, Alex; Tapper, Alexander; Tourneur, Stephane; Vazquez Acosta, Monica; Virdee, Tejinder; Wakefield, Stuart; Wardrope, David; Whyntie, Tom; Barrett, Matthew; Chadwick, Matthew; Cole, Joanne; Hobson, Peter R.; Khan, Akram; Kyberd, Paul; Leslie, Dawn; Martin, William; Reid, Ivan; Teodorescu, Liliana; Hatakeyama, Kenichi; Bose, Tulika; Carrera Jarrin, Edgar; Clough, Andrew; Fantasia, Cory; Heister, Arno; St. John, Jason; Lawson, Philip; Lazic, Dragoslav; Rohlf, James; Sperka, David; Sulak, Lawrence; Avetisyan, Aram; Bhattacharya, Saptaparna; Chou, John Paul; Cutts, David; Ferapontov, Alexey; Heintz, Ulrich; Jabeen, Shabnam; Kukartsev, Gennadiy; Landsberg, Greg; Narain, Meenakshi; Nguyen, Duong; Segala, Michael; Speer, Thomas; Tsang, Ka Vang; Borgia, Maria Assunta; Breedon, Richard; Calderon De La Barca Sanchez, Manuel; Cebra, Daniel; Chauhan, Sushil; Chertok, Maxwell; Conway, John; Cox, Peter Timothy; Dolen, James; Erbacher, Robin; Friis, Evan; Ko, Winston; Kopecky, Alexandra; Lander, Richard; Liu, Haidong; Maruyama, Sho; Miceli, Tia; Nikolic, Milan; Pellett, Dave; Robles, Jorge; Salur, Sevil; Schwarz, Thomas; Searle, Matthew; Smith, John; Squires, Michael; Tripathi, Mani; Vasquez Sierra, Ricardo; Veelken, Christian; Andreev, Valeri; Arisaka, Katsushi; Cline, David; Cousins, Robert; Deisher, Amanda; Duris, Joseph; Erhan, Samim; Farrell, Chris; Hauser, Jay; Ignatenko, Mikhail; Jarvis, Chad; Plager, Charles; Rakness, Gregory; Schlein, Peter; Tucker, Jordan; Valuev, Vyacheslav; Babb, John; Clare, Robert; Ellison, John Anthony; Gary, J William; Giordano, Ferdinando; Hanson, Gail; Jeng, Geng-Yuan; Kao, Shih-Chuan; Liu, Feng; Liu, Hongliang; Luthra, Arun; Nguyen, Harold; Pasztor, Gabriella; Satpathy, Asish; Shen, Benjamin C.; Stringer, Robert; Sturdy, Jared; Sumowidagdo, Suharyo; Wilken, Rachel; Wimpenny, Stephen; Andrews, Warren; Branson, James G.; Cerati, Giuseppe Benedetto; Dusinberre, Elizabeth; Evans, David; Golf, Frank; Holzner, André; Kelley, Ryan; Lebourgeois, Matthew; Letts, James; Mangano, Boris; Muelmenstaedt, Johannes; Padhi, Sanjay; Palmer, Christopher; Petrucciani, Giovanni; Pi, Haifeng; Pieri, Marco; Ranieri, Riccardo; Sani, Matteo; Sharma, Vivek; Simon, Sean; Tu, Yanjun; Vartak, Adish; Würthwein, Frank; Yagil, Avraham; Barge, Derek; Bellan, Riccardo; Campagnari, Claudio; D'Alfonso, Mariarosaria; Danielson, Thomas; Flowers, Kristen; Geffert, Paul; Incandela, Joe; Justus, Christopher; Kalavase, Puneeth; Koay, Sue Ann; Kovalskyi, Dmytro; Krutelyov, Vyacheslav; Lowette, Steven; Mccoll, Nickolas; Pavlunin, Viktor; Rebassoo, Finn; Ribnik, Jacob; Richman, Jeffrey; Rossin, Roberto; Stuart, David; To, Wing; Vlimant, Jean-Roch; Bornheim, Adolf; Bunn, Julian; Chen, Yi; Gataullin, Marat; Kcira, Dorian; Litvine, Vladimir; Ma, Yousi; Mott, Alexander; Newman, Harvey B.; Rogan, Christopher; Timciuc, Vladlen; Traczyk, Piotr; Veverka, Jan; Wilkinson, Richard; Yang, Yong; Zhu, Ren-Yuan; Akgun, Bora; Carroll, Ryan; Ferguson, Thomas; Iiyama, Yutaro; Jang, Dong Wook; Jun, Soon Yung; Liu, Yueh-Feng; Paulini, Manfred; Russ, James; Terentyev, Nikolay; Vogel, Helmut; Vorobiev, Igor; Cumalat, John Perry; Dinardo, Mauro Emanuele; Drell, Brian Robert; Edelmaier, Christopher; Ford, William T.; Heyburn, Bernadette; Luiggi Lopez, Eduardo; Nauenberg, Uriel; Smith, James; Stenson, Kevin; Ulmer, Keith; Wagner, Stephen Robert; Zang, Shi-Lei; Agostino, Lorenzo; Alexander, James; Chatterjee, Avishek; Das, Souvik; Eggert, Nicholas; Fields, Laura Johanna; Gibbons, Lawrence Kent; Heltsley, Brian; Hopkins, Walter; Khukhunaishvili, Aleko; Kreis, Benjamin; Kuznetsov, Valentin; Nicolas Kaufman, Gala; Patterson, Juliet Ritchie; Puigh, Darren; Riley, Daniel; Ryd, Anders; Shi, Xin; Sun, Werner; Teo, Wee Don; Thom, Julia; Thompson, Joshua; Vaughan, Jennifer; Weng, Yao; Winstrom, Lucas; Wittich, Peter; Biselli, Angela; Cirino, Guy; Winn, Dave; Abdullin, Salavat; Albrow, Michael; Anderson, Jacob; Apollinari, Giorgio; Atac, Muzaffer; Bakken, Jon Alan; Banerjee, Sunanda; Bauerdick, Lothar A.T.; Beretvas, Andrew; Berryhill, Jeffrey; Bhat, Pushpalatha C.; Bloch, Ingo; Borcherding, Frederick; Burkett, Kevin; Butler, Joel Nathan; Chetluru, Vasundhara; Cheung, Harry; Chlebana, Frank; Cihangir, Selcuk; Demarteau, Marcel; Eartly, David P.; Elvira, Victor Daniel; Esen, Selda; Fisk, Ian; Freeman, Jim; Gao, Yanyan; Gottschalk, Erik; Green, Dan; Gunthoti, Kranti; Gutsche, Oliver; Hahn, Alan; Hanlon, Jim; Harris, Robert M.; Hirschauer, James; Hooberman, Benjamin; James, Eric; Jensen, Hans; Johnson, Marvin; Joshi, Umesh; Khatiwada, Rakshya; Kilminster, Benjamin; Klima, Boaz; Kousouris, Konstantinos; Kunori, Shuichi; Kwan, Simon; Limon, Peter; Lipton, Ron; Lykken, Joseph; Maeshima, Kaori; Marraffino, John Michael; Mason, David; McBride, Patricia; McCauley, Thomas; Miao, Ting; Mishra, Kalanand; Mrenna, Stephen; Musienko, Yuri; Newman-Holmes, Catherine; O'Dell, Vivian; Popescu, Sorina; Pordes, Ruth; Prokofyev, Oleg; Saoulidou, Niki; Sexton-Kennedy, Elizabeth; Sharma, Seema; Soha, Aron; Spalding, William J.; Spiegel, Leonard; Tan, Ping; Taylor, Lucas; Tkaczyk, Slawek; Uplegger, Lorenzo; Vaandering, Eric Wayne; Vidal, Richard; Whitmore, Juliana; Wu, Weimin; Yang, Fan; Yumiceva, Francisco; Yun, Jae Chul; Acosta, Darin; Avery, Paul; Bourilkov, Dimitri; Chen, Mingshui; Di Giovanni, Gian Piero; Dobur, Didar; Drozdetskiy, Alexey; Field, Richard D.; Fisher, Matthew; Fu, Yu; Furic, Ivan-Kresimir; Gartner, Joseph; Goldberg, Sean; Kim, Bockjoo; Klimenko, Sergey; Konigsberg, Jacobo; Korytov, Andrey; Kropivnitskaya, Anna; Kypreos, Theodore; Matchev, Konstantin; Mitselmakher, Guenakh; Muniz, Lana; Pakhotin, Yuriy; Prescott, Craig; Remington, Ronald; Schmitt, Michael Houston; Scurlock, Bobby; Sellers, Paul; Skhirtladze, Nikoloz; Wang, Dayong; Yelton, John; Zakaria, Mohammed; Ceron, Cristobal; Gaultney, Vanessa; Kramer, Laird; Lebolo, Luis Miguel; Linn, Stephan; Markowitz, Pete; Martinez, German; Rodriguez, Jorge Luis; Adams, Todd; Askew, Andrew; Bandurin, Dmitry; Bochenek, Joseph; Chen, Jie; Diamond, Brendan; Gleyzer, Sergei V; Haas, Jeff; Hagopian, Sharon; Hagopian, Vasken; Jenkins, Merrill; Johnson, Kurtis F.; Prosper, Harrison; Sekmen, Sezen; Veeraraghavan, Venkatesh; Baarmand, Marc M.; Dorney, Brian; Guragain, Samir; Hohlmann, Marcus; Kalakhety, Himali; Ralich, Robert; Vodopiyanov, Igor; Adams, Mark Raymond; Anghel, Ioana Maria; Apanasevich, Leonard; Bai, Yuting; Bazterra, Victor Eduardo; Betts, Russell Richard; Callner, Jeremy; Cavanaugh, Richard; Dragoiu, Cosmin; Garcia-Solis, Edmundo Javier; Gerber, Cecilia Elena; Hofman, David Jonathan; Khalatyan, Samvel; Lacroix, Florent; O'Brien, Christine; Silvestre, Catherine; Smoron, Agata; Strom, Derek; Varelas, Nikos; Akgun, Ugur; Albayrak, Elif Asli; Bilki, Burak; Cankocak, Kerem; Clarida, Warren; Duru, Firdevs; Lae, Chung Khim; McCliment, Edward; Merlo, Jean-Pierre; Mermerkaya, Hamit; Mestvirishvili, Alexi; Moeller, Anthony; Nachtman, Jane; Newsom, Charles Ray; Norbeck, Edwin; Olson, Jonathan; Onel, Yasar; Ozok, Ferhat; Sen, Sercan; Wetzel, James; Yetkin, Taylan; Yi, Kai; Barnett, Bruce Arnold; Blumenfeld, Barry; Bonato, Alessio; Eskew, Christopher; Fehling, David; Giurgiu, Gavril; Gritsan, Andrei; Guo, Zijin; Hu, Guofan; Maksimovic, Petar; Rappoccio, Salvatore; Swartz, Morris; Tran, Nhan Viet; Whitbeck, Andrew; Baringer, Philip; Bean, Alice; Benelli, Gabriele; Grachov, Oleg; Murray, Michael; Noonan, Daniel; Radicci, Valeria; Sanders, Stephen; Wood, Jeffrey Scott; Zhukova, Victoria; Bolton, Tim; Chakaberia, Irakli; Ivanov, Andrew; Makouski, Mikhail; Maravin, Yurii; Shrestha, Shruti; Svintradze, Irakli; Wan, Zongru; Gronberg, Jeffrey; Lange, David; Wright, Douglas; Baden, Drew; Boutemeur, Madjid; Eno, Sarah Catherine; Ferencek, Dinko; Gomez, Jaime; Hadley, Nicholas John; Kellogg, Richard G.; Kirn, Malina; Lu, Ying; Mignerey, Alice; Rossato, Kenneth; Rumerio, Paolo; Santanastasio, Francesco; Skuja, Andris; Temple, Jeffrey; Tonjes, Marguerite; Tonwar, Suresh C.; Twedt, Elizabeth; Alver, Burak; Bauer, Gerry; Bendavid, Joshua; Busza, Wit; Butz, Erik; Cali, Ivan Amos; Chan, Matthew; Dutta, Valentina; Everaerts, Pieter; Gomez Ceballos, Guillelmo; Goncharov, Maxim; Hahn, Kristan Allan; Harris, Philip; Kim, Yongsun; Klute, Markus; Lee, Yen-Jie; Li, Wei; Loizides, Constantinos; Luckey, Paul David; Ma, Teng; Nahn, Steve; Paus, Christoph; Ralph, Duncan; Roland, Christof; Roland, Gunther; Rudolph, Matthew; Stephans, George; Sumorok, Konstanty; Sung, Kevin; Wenger, Edward Allen; Xie, Si; Yang, Mingming; Yilmaz, Yetkin; Yoon, Sungho; Zanetti, Marco; Cole, Perrie; Cooper, Seth; Cushman, Priscilla; Dahmes, Bryan; De Benedetti, Abraham; Dudero, Phillip Russell; Franzoni, Giovanni; Haupt, Jason; Klapoetke, Kevin; Kubota, Yuichi; Mans, Jeremy; Rekovic, Vladimir; Rusack, Roger; Sasseville, Michael; Singovsky, Alexander; Cremaldi, Lucien Marcus; Godang, Romulus; Kroeger, Rob; Perera, Lalith; Rahmat, Rahmat; Sanders, David A; Summers, Don; Bloom, Kenneth; Bose, Suvadeep; Butt, Jamila; Claes, Daniel R.; Dominguez, Aaron; Eads, Michael; Keller, Jason; Kelly, Tony; Kravchenko, Ilya; Lazo-Flores, Jose; Lundstedt, Carl; Malbouisson, Helena; Malik, Sudhir; Snow, Gregory R.; Baur, Ulrich; Godshalk, Andrew; Iashvili, Ia; Kharchilava, Avto; Kumar, Ashish; Shipkowski, Simon Peter; Smith, Kenneth; Alverson, George; Barberis, Emanuela; Baumgartel, Darin; Boeriu, Oana; Chasco, Matthew; Kaadze, Ketino; Reucroft, Steve; Swain, John; Wood, Darien; Zhang, Jinzhong; Anastassov, Anton; Kubik, Andrew; Odell, Nathaniel; Ofierzynski, Radoslaw Adrian; Pollack, Brian; Pozdnyakov, Andrey; Schmitt, Michael Henry; Stoynev, Stoyan; Velasco, Mayda; Won, Steven; Antonelli, Louis; Berry, Douglas; Hildreth, Michael; Jessop, Colin; Karmgard, Daniel John; Kolb, Jeff; Kolberg, Ted; Lannon, Kevin; Luo, Wuming; Lynch, Sean; Marinelli, Nancy; Morse, David Michael; Pearson, Tessa; Ruchti, Randy; Slaunwhite, Jason; Valls, Nil; Warchol, Jadwiga; Wayne, Mitchell; Ziegler, Jill; Bylsma, Ben; Durkin, Lloyd Stanley; Gu, Jianhui; Hill, Christopher; Killewald, Phillip; Kotov, Khristian; Ling, Ta-Yung; Rodenburg, Marissa; Williams, Grayson; Adam, Nadia; Berry, Edmund; Elmer, Peter; Gerbaudo, Davide; Halyo, Valerie; Hebda, Philip; Hunt, Adam; Jones, John; Laird, Edward; Lopes Pegna, David; Marlow, Daniel; Medvedeva, Tatiana; Mooney, Michael; Olsen, James; Piroué, Pierre; Quan, Xiaohang; Saka, Halil; Stickland, David; Tully, Christopher; Werner, Jeremy Scott; Zuranski, Andrzej; Acosta, Jhon Gabriel; Huang, Xing Tao; Lopez, Angel; Mendez, Hector; Oliveros, Sandra; Ramirez Vargas, Juan Eduardo; Zatserklyaniy, Andriy; Alagoz, Enver; Barnes, Virgil E.; Bolla, Gino; Borrello, Laura; Bortoletto, Daniela; Everett, Adam; Garfinkel, Arthur F.; Gecse, Zoltan; Gutay, Laszlo; Hu, Zhen; Jones, Matthew; Koybasi, Ozhan; Laasanen, Alvin T.; Leonardo, Nuno; Liu, Chang; Maroussov, Vassili; Merkel, Petra; Miller, David Harry; Neumeister, Norbert; Potamianos, Karolos; Shipsey, Ian; Silvers, David; Svyatkovskiy, Alexey; Yoo, Hwi Dong; Zablocki, Jakub; Zheng, Yu; Jindal, Pratima; Parashar, Neeti; Boulahouache, Chaouki; Cuplov, Vesna; Ecklund, Karl Matthew; Geurts, Frank J.M.; Liu, Jinghua H.; Morales, Jafet; Padley, Brian Paul; Redjimi, Radia; Roberts, Jay; Zabel, James; Betchart, Burton; Bodek, Arie; Chung, Yeon Sei; Covarelli, Roberto; de Barbaro, Pawel; Demina, Regina; Eshaq, Yossof; Flacher, Henning; Garcia-Bellido, Aran; Goldenzweig, Pablo; Gotra, Yury; Han, Jiyeon; Harel, Amnon; Miner, Daniel Carl; Orbaker, Douglas; Petrillo, Gianluca; Vishnevskiy, Dmitry; Zielinski, Marek; Bhatti, Anwar; Demortier, Luc; Goulianos, Konstantin; Lungu, Gheorghe; Mesropian, Christina; Yan, Ming; Atramentov, Oleksiy; Barker, Anthony; Duggan, Daniel; Gershtein, Yuri; Gray, Richard; Halkiadakis, Eva; Hidas, Dean; Hits, Dmitry; Lath, Amitabh; Panwalkar, Shruti; Patel, Rishi; Richards, Alan; Rose, Keith; Schnetzer, Steve; Somalwar, Sunil; Stone, Robert; Thomas, Scott; Cerizza, Giordano; Hollingsworth, Matthew; Spanier, Stefan; Yang, Zong-Chang; York, Andrew; Asaadi, Jonathan; Eusebi, Ricardo; Gilmore, Jason; Gurrola, Alfredo; Kamon, Teruki; Khotilovich, Vadim; Montalvo, Roy; Nguyen, Chi Nhan; Osipenkov, Ilya; Pivarski, James; Safonov, Alexei; Sengupta, Sinjini; Tatarinov, Aysen; Toback, David; Weinberger, Michael; Akchurin, Nural; Bardak, Cemile; Damgov, Jordan; Jeong, Chiyoung; Kovitanggoon, Kittikul; Lee, Sung Won; Mane, Poonam; Roh, Youn; Sill, Alan; Volobouev, Igor; Wigmans, Richard; Yazgan, Efe; Appelt, Eric; Brownson, Eric; Engh, Daniel; Florez, Carlos; Gabella, William; Johns, Willard; Kurt, Pelin; Maguire, Charles; Melo, Andrew; Sheldon, Paul; Velkovska, Julia; Arenton, Michael Wayne; Balazs, Michael; Boutle, Sarah; Buehler, Marc; Conetti, Sergio; Cox, Bradley; Francis, Brian; Hirosky, Robert; Ledovskoy, Alexander; Lin, Chuanzhe; Neu, Christopher; Yohay, Rachel; Gollapinni, Sowjanya; Harr, Robert; Karchin, Paul Edmund; Lamichhane, Pramod; Mattson, Mark; Milstène, Caroline; Sakharov, Alexandre; Anderson, Michael; Bachtis, Michail; Bellinger, James Nugent; Carlsmith, Duncan; Dasu, Sridhara; Efron, Jonathan; Gray, Lindsey; Grogg, Kira Suzanne; Grothe, Monika; Hall-Wilton, Richard; Herndon, Matthew; Klabbers, Pamela; Klukas, Jeffrey; Lanaro, Armando; Lazaridis, Christos; Leonard, Jessica; Lomidze, David; Loveless, Richard; Mohapatra, Ajit; Reeder, Don; Ross, Ian; Savin, Alexander; Smith, Wesley H.; Swanson, Joshua; Weinberg, Marc

    2011-01-01

    The result of a search at the LHC for heavy stable charged particles produced in pp collisions at sqrt(s) = 7 TeV is described. The data sample was collected with the CMS detector and corresponds to an integrated luminosity of 3.1 inverse picobarns. Momentum and ionization-energy-loss measurements in the inner tracker detector are used to identify tracks compatible with heavy slow-moving particles. Additionally, tracks passing muon identification requirements are also analyzed for the same signature. In each case, no candidate passes the selection, with an expected background of less than 0.1 events. A lower limit at the 95% confidence level on the mass of a stable gluino is set at 398 GeV/c2, using a conventional model of nuclear interactions that allows charged hadrons containing this particle to reach the muon detectors. A lower limit of 311 GeV/c2 is also set for a stable gluino in a conservative scenario of complete charge suppression, where any hadron containing this particle becomes neutral before rea...

  13. 3D-structured illumination microscopy reveals clustered DNA double-strand break formation in widespread γH2AX foci after high LET heavy-ion particle radiation.

    Science.gov (United States)

    Hagiwara, Yoshihiko; Niimi, Atsuko; Isono, Mayu; Yamauchi, Motohiro; Yasuhara, Takaaki; Limsirichaikul, Siripan; Oike, Takahiro; Sato, Hiro; Held, Kathryn D; Nakano, Takashi; Shibata, Atsushi

    2017-12-12

    DNA double-strand breaks (DSBs) induced by ionising radiation are considered the major cause of genotoxic mutations and cell death. While DSBs are dispersed throughout chromatin after X-rays or γ-irradiation, multiple types of DNA damage including DSBs, single-strand breaks and base damage can be generated within 1-2 helical DNA turns, defined as a complex DNA lesion, after high Linear Energy Transfer (LET) particle irradiation. In addition to the formation of complex DNA lesions, recent evidence suggests that multiple DSBs can be closely generated along the tracks of high LET particle irradiation. Herein, by using three dimensional (3D)-structured illumination microscopy, we identified the formation of 3D widespread γH2AX foci after high LET carbon-ion irradiation. The large γH2AX foci in G 2 -phase cells encompassed multiple foci of replication protein A (RPA), a marker of DSBs undergoing resection during homologous recombination. Furthermore, we demonstrated by 3D analysis that the distance between two individual RPA foci within γH2AX foci was approximately 700 nm. Together, our findings suggest that high LET heavy-ion particles induce clustered DSB formation on a scale of approximately 1 μm 3 . These closely localised DSBs are considered to be a risk for the formation of chromosomal rearrangement after heavy-ion irradiation.

  14. Effects of Heavy particle ray on regeneration and reproduction with planarian

    International Nuclear Information System (INIS)

    Watanabe, Kaori; Matsumoto, Midori; Nojima, Kumie

    2006-01-01

    Space age is coming and many topics on cosmic space are pointed out like zero gravity and cosmic ray. Planarian is one of the attractive organisms, which could be a useful laboratory animal for space science. It is famous for its remarkable regeneration ability by pluripotent stem cells called neoblast. And they can produce their offspring by asexual reproduction and sexual reproduction. In this study, we focused on effects of the cosmic ray on the regeneration and the reproduction with planarian. As it has known that the major effective cosmic ray is a heavy particle ray, effects of the heavy particle ray on the regeneration and the reproduction was researched with C290, which is carbon ion beam, and Fe500, which is iron ion beam. In asexual reproduction worms, the irradiations of both beams had effects on dose dependency. The minimum lethal doses of both beams were 6 Gy and their neoblasts were disappeared. And in sexual reproduction worms, the irradiations of both beams also effects on dose dependency and the minimum lethal doses were 12 Gy. It showed that the relative biological effectiveness is different on the reproduction system in planarian. (author)

  15. Clustered DNA damage induced by proton and heavy ion irradiation

    International Nuclear Information System (INIS)

    Davidkova, M.; Pachnerova Brabcova, K; Stepan, V.; Vysin, L.; Sihver, L.; Incerti, S.

    2014-01-01

    Ionizing radiation induces in DNA strand breaks, damaged bases and modified sugars, which accumulate with increasing density of ionizations in charged particle tracks. Compared to isolated DNA damage sites, the biological toxicity of damage clusters can be for living cells more severe. We investigated the clustered DNA damage induced by protons (30 MeV) and high LET radiation (C 290 MeV/u and Fe 500 MeV/u) in pBR322 plasmid DNA. To distinguish between direct and indirect pathways of radiation damage, the plasmid was irradiated in pure water or in aqueous solution of one of the three scavengers (coumarin-3-carboxylic acid, dimethylsulfoxide, and glycylglycine). The goal of the contribution is the analysis of determined types of DNA damage in dependence on radiation quality and related contribution of direct and indirect radiation effects. The yield of double strand breaks (DSB) induced in the DNA plasmid-scavenger system by heavy ion radiation was found to decrease with increasing scavenging capacity due to reaction with hydroxyl radical, linearly with high correlation coefficients. The yield of non-DSB clusters was found to occur twice as much as the DSB. Their decrease with increasing scavenging capacity had lower linear correlation coefficients. This indicates that the yield of non-DSB clusters depends on more factors, which are likely connected to the chemical properties of individual scavengers. (authors)

  16. Search for Heavy Stable Charged Particles at $\\sqrt{s}$ = 13 TeV Utilizing a Multivariate Approach

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00375809

    Heavy stable charged particles (HSCPs) have been searched for at the Large Hadron Collider since its initial data taking in 2010. The search for heavy stable charged particles provide a means of directly probing the new physics realm, as they produce a detector signature unlike any particle discovered to date. The goal of this research is to investigate an idea that was introduced in the later stages of 2010-2012 data taking period. Rather than utilizing the current tight selection on the calculated particle mass the hypothesis is that by incorporating a multivariate approach, specif- ically an artificial neural network, the remaining selection criteria could be loosened allowing for a greater signal acceptance while maintaining acceptable background rejection via the multivariate discriminator from the artificial neural network. The increase in signal acceptance and retention or increase in background rejection increases the discovery potential for HSCPs and as a secondary objective calculates improved limit...

  17. Characterization of the Particle Size Fraction associated with Heavy Metals in Suspended Sediments of the Yellow River

    Directory of Open Access Journals (Sweden)

    Qingzhen Yao

    2015-06-01

    Full Text Available Variations in the concentrations of particulate heavy metals and fluxes into the sea in the Yellow River were examined based on observational and measured data from January 2009 to December 2010. A custom-built water elutriation apparatus was used to separate suspended sediments into five size fractions. Clay and very fine silt is the dominant fraction in most of the suspended sediments, accounting for >40% of the samples. Cu, Pb, Zn, Cr, Fe and Mn are slightly affected by anthropogenic activities, while Cd is moderate affected. The concentrations of heavy metals increased with decrease in particle size. For suspended sediments in the Yellow River, on average 78%–82% of the total heavy metal loading accumulated in the <16 μm fraction. About 43% and 53% of heavy metal in 2009 and 2010 respectively, were readily transported to the Bohai Sea with “truly suspended” particles, which have potentially harmful effects on marine organisms.

  18. Solid Particle Number Emission Factors of Euro VI Heavy-Duty Vehicles on the Road and in the Laboratory

    Science.gov (United States)

    Giechaskiel, Barouch

    2018-01-01

    Particulate matter (PM), and in particular ultrafine particles, have a negative impact on human health. The contribution of vehicle PM emissions to air pollution is typically quantified with emission inventories, which need vehicle emission factors as input. Heavy-duty vehicles, although they represent a small percentage of the vehicle population in nearly every major country, contribute the majority of the on-road PM emissions. However, the published data of modern heavy-duty vehicle emissions are scarce, and for the newest Euro VI technologies, almost non-existent. The main objective of this paper is to present Solid Particle Number (SPN) emission factors from Euro VI heavy-duty vehicles using diesel, Compressed Natural Gas (CNG), or Liquefied Natural Gas (LNG). Urban, rural and motorway (highway) emissions were determined on the road at various European cities using SPN Portable Emission Measurement Systems (PEMS). Additional tests on a heavy-duty chassis dynamometer showed that the solid sub-23 nm fraction, which is not covered at the moment in the European regulation, is high, especially for CNG engines. The significant contribution of regeneration events and the effect of ambient temperature and engine cold-start on particle emissions were also discussed. PMID:29425174

  19. Solid Particle Number Emission Factors of Euro VI Heavy-Duty Vehicles on the Road and in the Laboratory

    Directory of Open Access Journals (Sweden)

    Barouch Giechaskiel

    2018-02-01

    Full Text Available Particulate matter (PM, and in particular ultrafine particles, have a negative impact on human health. The contribution of vehicle PM emissions to air pollution is typically quantified with emission inventories, which need vehicle emission factors as input. Heavy-duty vehicles, although they represent a small percentage of the vehicle population in nearly every major country, contribute the majority of the on-road PM emissions. However, the published data of modern heavy-duty vehicle emissions are scarce, and for the newest Euro VI technologies, almost non-existent. The main objective of this paper is to present Solid Particle Number (SPN emission factors from Euro VI heavy-duty vehicles using diesel, Compressed Natural Gas (CNG, or Liquefied Natural Gas (LNG. Urban, rural and motorway (highway emissions were determined on the road at various European cities using SPN Portable Emission Measurement Systems (PEMS. Additional tests on a heavy-duty chassis dynamometer showed that the solid sub-23 nm fraction, which is not covered at the moment in the European regulation, is high, especially for CNG engines. The significant contribution of regeneration events and the effect of ambient temperature and engine cold-start on particle emissions were also discussed.

  20. Solid Particle Number Emission Factors of Euro VI Heavy-Duty Vehicles on the Road and in the Laboratory.

    Science.gov (United States)

    Giechaskiel, Barouch

    2018-02-09

    Particulate matter (PM), and in particular ultrafine particles, have a negative impact on human health. The contribution of vehicle PM emissions to air pollution is typically quantified with emission inventories, which need vehicle emission factors as input. Heavy-duty vehicles, although they represent a small percentage of the vehicle population in nearly every major country, contribute the majority of the on-road PM emissions. However, the published data of modern heavy-duty vehicle emissions are scarce, and for the newest Euro VI technologies, almost non-existent. The main objective of this paper is to present Solid Particle Number (SPN) emission factors from Euro VI heavy-duty vehicles using diesel, Compressed Natural Gas (CNG), or Liquefied Natural Gas (LNG). Urban, rural and motorway (highway) emissions were determined on the road at various European cities using SPN Portable Emission Measurement Systems (PEMS). Additional tests on a heavy-duty chassis dynamometer showed that the solid sub-23 nm fraction, which is not covered at the moment in the European regulation, is high, especially for CNG engines. The significant contribution of regeneration events and the effect of ambient temperature and engine cold-start on particle emissions were also discussed.

  1. Somatic mutation in larvae of the silkworm, Bombyx mori, induced by heavy ion irradiation to diapause eggs

    Energy Technology Data Exchange (ETDEWEB)

    Kotani, Eiji; Furusawa, Toshiharu [Kyoto Inst. of Tech. (Japan). Faculty of Textile Science; Nagaoka, Shunji [Fujita Health Univ., Toyoake, Aichi (Japan). School of Health Sciences] [and others

    2002-12-01

    In order to investigate whether eggs of the black-striped strain (P{sup S}) of the silkworm, Bombyx mori, represent an appropriate model for estimating the biological effect of cosmic radiation, radiosensitivity of the eggs against X-rays and heavy ion particles was examined as ground-based experiments. The exposure of diapause eggs to X-rays or heavy ion particles resulted in somatic mutations appearing as a white spot on the black integument during larval stage. Irradiation of non-diapause eggs with X-rays demonstrated a significant difference in frequency of the mutation between fractionated and single administration doses, but no difference was observed in diapause eggs. Incidence of the mutation as induced by carbon ion beams for 15-day old eggs was higher for eggs that had been kept at 15 deg C than those kept at 25 deg C. Neon beam irradiation of diapause eggs displayed dose- and linear energy transfer (LET)-dependent effects, causing a maximal rate of the mutation at 150 keV/{mu}m. These results confirm that B. mori eggs represent valid models for estimating the biological effects of cosmic radiation. (author)

  2. Light particle and gamma ray emission measurements in heavy-ion reactions. Progress report

    International Nuclear Information System (INIS)

    Petitt, G.A.

    1982-01-01

    The development of a position-sensitive neutron detector and a data acquisition system at HHIRF for studying light particle emission in heavy ion reactions is described. Results are presented and discussed for the reactions 12 C + 158 Gd, 13 C + 157 Gd, and 20 Ne + 150 Nd

  3. Multifragmentation in intermediate energy 129Xe-induced heavy-ion reactions

    International Nuclear Information System (INIS)

    Tso, Kin.

    1996-05-01

    The 129 Xe-induced reactions on nat Cu, 89 Y, 165 Ho, and 197 Au at bombarding energies of E/A = 40 ampersand 60 MeV have been studied theoretically and experimentally in order to establish the underlying mechanism of multifragmentation at intermediate energy heavy-Ion collisions. Nuclear disks formed in central heavy-ion collisions, as simulated by means of Boltzmann-like kinetic equations, break up into several fragments due to a new kind of Rayleigh-like surface instability. A sheet of liquid, stable in the limit of non-interacting surfaces, is shown to become unstable due to surface-surface interactions. The onset of this instability is determined analytically. A thin bubble behaves like a sheet and is susceptible to the surface instability through the crispation mode. The Coulomb effects associated with the depletion of charges in the central cavity of nuclear bubbles are investigated. The onset of Coulomb instability is demonstrated for perturbations of the radial mode. Experimental intermediate-mass-fragment multiplicity distributions for the 129 Xe-induced reactions are shown to be binomial at each transverse energy. From these distributions, independent of the specific target, an elementary binary decay probability p can be extracted that has a thermal dependence. Thus it is inferred that multifragmentation is reducible to a combination of nearly independent emission processes. If sequential decay is assumed, the increase of p with transverse energy implies a contraction of the emission time scale. The sensitivity of p to the lower Z threshold in the definition of intermediate-mass-fragments points to a physical Poisson simulations of the particle multiplicities show that the weak auto-correlation between the fragment multiplicity and the transverse energy does not distort a Poisson distribution into a binomial distribution. The effect of device efficiency on the experimental results has also been studied

  4. The effects of heavy particle irradiation on exploration and response to environmental change

    Science.gov (United States)

    Casadesus, G.; Shukitt-Hale, B.; Cantuti-Castelvetri, I.; Rabin, B.; Joseph, J.

    Free radicals produced by exposure to heavy particles have been found to produce motor and behavioral toxicity effects in rats similar to those found during aging. The present research was designed to investigate the effects of exposure to 56Fe particles on the ability to detect novel arrangements in a given environment of male Sprague-Dawley rats. Using a test of spatial memory previously demonstrated to be sensitive to aging, open-field activity and reaction to spatial and non-spatial changes were measured in a group that received a dose of 1.5 Gy (n=10) of 56Fe heavy particle radiation or in non- radiated controls. Animals irradiated with 1.5 Gy of56Fe particles exhibited some age-like effects in animals tested, even though they were for the most part, subtle. Animals took longer to enter, visited less and spent significantly less time in the middle and the center portions of the open-field independently of total frequency and duration of activity of both groups. Likewise, irradiated subjects reacted significantly more to novel objects placed in the open-field than did controls. However, irradiated subjects did not vary from controls in their exploration patterns when objects in the open-field were spatially rearranged. Thus, irradiation with a dose of 1.5 Gy of 56Fe high-energy particle radiation elicited age-like effects in general open-field exploratory behavior, but did not elicit age- like effects during the spatial and non-spatial rearrangement tasks. Supported by N.A.S.A. Grant NAG9-1190.

  5. Summary report on first research coordination meeting on heavy charged-particle interaction data for radiotherapy

    International Nuclear Information System (INIS)

    Palmans, H.; Noy, R.C.

    2008-04-01

    A summary is given of the First Research Coordination Meeting on Heavy Charged-Particle Interaction Data for Radiotherapy. A programme to compile and evaluate charged-particle nuclear data for therapeutic applications was proposed. Detailed coordinated research proposals were also agreed. Technical discussions and the resulting work plan of the Coordinated Research Project are summarized, along with actions and deadlines. (author)

  6. Systematics of Charged Particle Production in Heavy-Ion Collisions with the PHOBOS Detector at Rhic

    Science.gov (United States)

    Steinberg, Peter A.; Back, B. B.; Baker, M. D.; Barton, D. S.; Betts, R. R.; Bindel, R.; Budzanowski, A.; Busza, W.; Carroll, A.; Corbo, J.; Decowski, M. P.; Garcia, E.; George, N.; Gulbrandsen, K.; Gushue, S.; Halliwell, C.; Hamblen, J.; Henderson, C.; Hicks, D.; Hofman, D.; Hollis, R. S.; Hołyński, R.; Holzman, B.; Iordanova, A.; Johnson, E.; Kane, J.; Katzy, J.; Khan, N.; Kucewicz, W.; Kulinich, P.; Kuo, C. M.; Lin, W. T.; Manly, S.; McLeod, D.; Michałowski, J.; Mignerey, A.; Mülmenstädt, J.; Nouicer, R.; Olszewski, A.; Pak, R.; Park, I. C.; Pernegger, H.; Rafelski, M.; Rbeiz, M.; Reed, C.; Remsberg, L. P.; Reuter, M.; Roland, C.; Roland, G.; Rosenberg, L.; Sagerer, J.; Sarin, P.; Sawicki, P.; Skulski, W.; Steadman, S. G.; Steinberg, P.; Stephans, G. S. F.; Stodulski, M.; Sukhanov, A.; Tang, J.-L.; Teng, R.; Trzupek, A.; Vale, C.; van Nieuwenhuizen, G. J.; Verdier, R.; Wadsworth, B.; Wolfs, F. L. H.; Wosiek, B.; Woźniak, K.; Wuosmaa, A. H.; Wysłouch, B.

    2002-03-01

    The multiplicity of charged particles produced in Au+Au collisions as a function of energy, centrality, rapidity and azimuthal angle has been measured with the PHOBOS detector at RHIC. These results contribute to our understanding of the initial state of heavy ion collisions and provide a means to compare basic features of particle production in nuclear collisions with more elementary systems.

  7. Aerodynamic focusing of particles and heavy molecules: First annual report

    International Nuclear Information System (INIS)

    de la Mora, J.F.

    1988-01-01

    Our first goal was to investigate the phenomenon of aerodynamic focusing in supersonic free jets, in order to assess its potential technological uses in /open quotes/direct writing/close quotes/ and other energy-related applications. Our research program divides itself naturally into two chapters: on focusing microscopic particles, and on focusing individual molecules of heavy vapors carried in jets of He and H 2 . In both lines we combine diverse experimental and theoretical methods of attack. 3 refs., 4 figs

  8. DNA damage and repair in oncogenic transformation by heavy ion radiation

    Science.gov (United States)

    Yang, T. C.; Mei, M.; George, K. A.; Craise, L. M.

    1996-01-01

    Energetic heavy ions are present in galactic cosmic rays and solar particle events. One of the most important late effects in risk assessment is carcinogenesis. We have studied the carcinogenic effects of heavy ions at the cellular and molecular levels and have obtained quantitative data on dose-response curves and on the repair of oncogenic lesions for heavy particles with various charges and energies. Studies with repair inhibitors and restriction endonucleases indicated that for oncogenic transformation DNA is the primary target. Results from heavy ion experiments showed that the cross section increased with LET and reached a maximum value of about 0.02 micrometer2 at about 500 keV/micrometer. This limited size of cross section suggests that only a fraction of cellular genomic DNA is important in radiogenic transformation. Free radical scavengers, such as DMSO, do not give any effect on induction of oncogenic transformation by 600 MeV/u iron particles, suggesting most oncogenic damage induced by high-LET heavy ions is through direct action. Repair studies with stationary phase cells showed that the amount of reparable oncogenic lesions decreased with an increase of LET and that heavy ions with LET greater than 200 keV/micrometer produced only irreparable oncogenic damage. An enhancement effect for oncogenic transformation was observed in cells irradiated by low-dose-rate argon ions (400 MeV/u; 120 keV/micrometer). Chromosomal aberrations, such as translocation and deletion, but not sister chromatid exchange, are essential for heavy-ion-induced oncogenic transformation. The basic mechanism(s) of misrepair of DNA damage, which form oncogenic lesions, is unknown.

  9. Flow induced crystallisation of penetrable particles

    Science.gov (United States)

    Scacchi, Alberto; Brader, Joseph M.

    2018-03-01

    For a system of Brownian particles interacting via a soft exponential potential we investigate the interaction between equilibrium crystallisation and spatially varying shear flow. For thermodynamic state points within the liquid part of the phase diagram, but close to the crystallisation phase boundary, we observe that imposing a Poiseuille flow can induce nonequilibrium crystalline ordering in regions of low shear gradient. The physical mechanism responsible for this phenomenon is shear-induced particle migration, which causes particles to drift preferentially towards the center of the flow channel, thus increasing the local density in the channel center. The method employed is classical dynamical density functional theory.

  10. The role of particle-size soil fractions in the adsorption of heavy metals

    Science.gov (United States)

    Mandzhieva, Saglara; Minkina, Tatiana; Pinsky, David; Batukaev, Abdulmalik; Kalinitchenko, Valeriy; Sushkova, Svetlana; Chaplygin, Viktor; Dikaev, Zaurbek; Startsev, Viktor; Bakoev, Serojdin

    2014-05-01

    Ion-exchange adsorption phenomena are important in the immobilization of heavy metals (HMs) by soils. Numerous works are devoted to the study of this problem. However, the interaction features of different particle-size soil fractions and their role in the immobilization of HMs studied insufficiently. Therefore, the assessment of the effect of the particle-size distribution on the adsorption properties of soils is a vital task. The parameters of Cu2+, Pb2+ and Zn2+ adsorption by chernozems of the south of Russia and their particle-size fractions were studied. In the particle-size fractions separated from the soils, the concentrations of Cu2+, Pb2+, and Zn2 decreased with the decreasing particle size. The parameters of the adsorption values of k (the constant of the affinity)and Cmax.(the maximum adsorption of the HMs) characterizing the adsorption of HMs by the southern chernozem and its particle-size fractions formed the following sequence: silt > clay > entire soil. The adsorption capacity of chernozems for Cu2+, Pb2+, and Zn2+ depending on the particle-size distribution decreased in the following sequence: clay loamy ordinary chernozem clay loamy southern chernozem> loamy southern chernozem> loamy sandy southern chernozem. According to the parameters of the adsorption by the different particle-size fractions, the heavy metal cations form a sequence analogous to that obtained for the entire soils: Cu2+ ≥ Pb2+ > Zn2+. The parameters of the heavy metal adsorption by similar particle-size fractions separated from different soils decreased in the following order: clay loamy chernozem> loamy chernozem> loamy sandy chernozem. The analysis of the changes in the parameters of the Cu2+, Pb2+, and Zn2+ adsorption by the studied soils and their particle-size fractions showed that the extensive adsorption characteristic - the maximum adsorption (Cmax.) - is a less sensitive parameter characterizing the adsorption capacity of the soils than the intensive characteristic of

  11. Bibliography of ionization and stripping in heavy particle collisions, 1950--1975

    International Nuclear Information System (INIS)

    Hawthorne, S.W.; McDaniel, E.W.; Barnett, C.F.; Crandall, D.H.; Gilbody, H.B.; Kirkpatrick, M.I.; Phaneuf, R.A.; Thomas, E.W.

    1979-02-01

    This annotated bibliography lists published work on ionization and stripping in heavy particle collisions for the period 1950 to 1975. Sources include scientific journals, abstract compilations, conference proceedings, books, and reports. The bibliography is arranged alphabetically by author. Each entry indicates whether the work was experimental or theoretical, what energy range was covered, and what reactants were investigated. Following the bibliographical listing are indexes of reactants and authors

  12. Light particle emission measurements in heavy ion reactions: Progress report, June 1, 1987-May 31, 1988

    International Nuclear Information System (INIS)

    Petitt, G.A.

    1988-01-01

    This paper discusses work on heavy ion reactions done at Georgia State University. Topics and experiments discussed are: energy division in damped reactions between 58 Ni projectiles and 165 Ho and 58 Ni targets using time-of-flight methods; particle-particle correlations; and development works on the Hili detector system. 10 refs., 9 figs

  13. Multifragmentation induced by light relativistic projectiles and heavy ions: similarities and differences

    International Nuclear Information System (INIS)

    Karnaukhov, V.A.; Avdeev, S.P.; Kuznetsov, V.D.

    1998-01-01

    The experimental data on fragment multiplicities, their energy and charge distributions, the emission times are considered for the nuclear multifragmentation process induced by relativistic light projectiles (protons, helium) and heavy ions. With light projectiles, the multifragmentation is a pure 'thermal' process, well described by the statistical models. Heavy-ion-induced multifragmentation is influenced by dynamic effects related first of all to the compression of the system in the collision. But statistical models can also be applied to rendering the partition of the system if the excitation energy is less than 10 MeV/nucleon and compression is modest. For the central collision of heavy ions the statistical approach fails to describe the data

  14. Gauge bosons and heavy quarks: Proceedings of Summer Institute on Particle Physics

    Energy Technology Data Exchange (ETDEWEB)

    Hawthorne, J.F. (ed.)

    1991-01-01

    This report contains papers on the following topics: Z decays and tests of the standard model; future possibilities for LEP; studies of the interactions of electroweak gauge bosons; top quark topics; the next linear collider; electroweak processes in hadron colliders; theoretical topics in B-physics; experimental aspects of B-physics; B-factory storage ring design; rare kaon decays; CP violation in K{sup 0} decays at CERN; recent K{sup 0} decay results from Fermilab E-731; results from LEP on heavy quark physics; review of recent results on heavy flavor production; weak matrix elements and the determination of the weak mixing angles; recent results from CLEO I and a glance at CLEO II data; recent results from ARGUS; neutrino lepton physics with the CHARM 2 detector; recent results from the three TRISTAN experiments; baryon number violation at high energy in the standard model: fact or fiction New particle searches at LEP; review of QCD at LEP; electroweak interactions at LEP; recent results on W physics from the UA2 experiment at the CERN {rho}{bar {rho}} collider; B physics at CDF; and review of particle astrophysics.

  15. Gauge bosons and heavy quarks: Proceedings of Summer Institute on Particle Physics

    International Nuclear Information System (INIS)

    Hawthorne, J.F.

    1991-01-01

    This report contains papers on the following topics: Z decays and tests of the standard model; future possibilities for LEP; studies of the interactions of electroweak gauge bosons; top quark topics; the next linear collider; electroweak processes in hadron colliders; theoretical topics in B-physics; experimental aspects of B-physics; B-factory storage ring design; rare kaon decays; CP violation in K 0 decays at CERN; recent K 0 decay results from Fermilab E-731; results from LEP on heavy quark physics; review of recent results on heavy flavor production; weak matrix elements and the determination of the weak mixing angles; recent results from CLEO I and a glance at CLEO II data; recent results from ARGUS; neutrino lepton physics with the CHARM 2 detector; recent results from the three TRISTAN experiments; baryon number violation at high energy in the standard model: fact or fiction? New particle searches at LEP; review of QCD at LEP; electroweak interactions at LEP; recent results on W physics from the UA2 experiment at the CERN ρ bar ρ collider; B physics at CDF; and review of particle astrophysics

  16. Catapult mechanism for fast particle emission in fission and heavy ion reactions

    International Nuclear Information System (INIS)

    Maedler, P.

    1984-01-01

    The fission processes of slabs of nuclear matter is modelled in the Hartree-Fock time dependence approximation by adding an initial collective velocity field to the static self-consistent solution. In dependence on its amplitude either large amplitude density oscillations are excited or fission occurs. The final disintegration of the slab proceeds on a time scale 10 -22 s and is characterized by a sharp peak in the actual velocity field in the region of the ''snatching'' inner low density tails. A characteristic time later a low density lump correlated with a peak in the velocity field energies in front of the fragments. These particles are called ''catapult particles''. Recent experimental results possibly provide evidence for catapult neutrons in low-energy fission. The significance of the catapult mechanism for fast particle emission in the exit channel of heavy ion reactions is discussed

  17. Heavy ion therapy: Bevalac epoch

    International Nuclear Information System (INIS)

    Castro, J.R.

    1993-10-01

    An overview of heavy ion therapy at the Bevelac complex (SuperHILac linear accelerator + Bevatron) is given. Treatment planning, clinical results with helium ions on the skull base and uveal melanoma, clinical results with high-LET charged particles, neon radiotherapy of prostate cancer, heavy charged particle irradiation for unfavorable soft tissue sarcoma, preliminary results in heavy charged particle irradiation of bone sarcoma, and irradiation of bile duct carcinoma with charged particles and-or photons are all covered

  18. A Random-Walk-Model for heavy metal particles in natural waters; Ein Random-Walk-Modell fuer Schwermetallpartikel in natuerlichen Gewaessern

    Energy Technology Data Exchange (ETDEWEB)

    Wollschlaeger, A.

    1996-12-31

    The presented particle tracking model is for the numerical calculation of heavy metal transport in natural waters. The Navier-Stokes-Equations are solved with the Finite-Element-Method. The advective movement of the particles is interpolated from the velocities on the discrete mesh. The influence of turbulence is simulated with a Random-Walk-Model where particles are distributed due to a given probability function. Both parts are added and lead to the new particle position. The characteristics of the heavy metals are assigned to the particules as their attributes. Dissolved heavy metals are transported only by the flow. Heavy metals which are bound to particulate matter have an additional settling velocity. The sorption and the remobilization processes are approximated through a probability law which maintains the proportionality ratio between dissolved heavy metals and those which are bound to particulate matter. At the bed heavy metals bound to particulate matter are subjected to deposition and erosion processes. The model treats these processes by considering the absorption intensity of the heavy metals to the bottom sediments. Calculations of the Weser estuary show that the particle tracking model allows the simulation of the heavy metal behaviour even under complex flow conditions. (orig.) [Deutsch] Das vorgestellte Partikelmodell dient zur numerischen Berechnung des Schwermetalltransports in natuerlichen Gewaessern. Die Navier-Stokes-Gleichungen werden mit der Methode der Finiten Elemente geloest. Die advektive Bewegung der Teilchen ergibt sich aus der Interpolation der Geschwindigkeiten auf dem diskreten Netz. Der Einfluss der Turbulenz wird mit einem Random-Walk-Modell simuliert, bei dem sich die Partikel anhand einer vorgegebenen Wahrscheinlichkeitsfunktion verteilen. Beide Bewegungsanteile werden zusammengefasst und ergeben die neue Partikelposition. Die Eigenschaften der Schwermetalle werden den Partikeln als Attribute zugeordnet. Geloeste Schwermetalle

  19. Working group report: Heavy-ion physics and quark-gluon plasma

    Indian Academy of Sciences (India)

    High energy photons from relativistic heavy ion collider: Dinesh K Srivastava. 7. On the ..... use them it is mandatory to measure very low-energy particles and to ..... moving test charge resulting in a wake in the induced charge due to dynamical.

  20. Generating heavy particles with energy and momentum conservation

    Science.gov (United States)

    Mereš, Michal; Melo, Ivan; Tomášik, Boris; Balek, Vladimír; Černý, Vladimír

    2011-12-01

    -body decays of heavy resonances. After all momenta are generated this way, they are reshuffled. Each particle undergoes a collision with some other partner such that in the pair center of mass system the new directions of momenta are distributed isotropically. After each particle collides only a few times, the momenta are distributed evenly across the whole available phase space. Starting with GENBOD is not essential for the procedure but it improves the performance. Running time: This depends on the number of particles and number of events one wants to generate. On a LINUX PC with 2 GHz processor, generation of 1000 events with 10 particles each takes about 3 s.

  1. The Responses of Antioxidant System against the Heavy Metal-Induced Stress in Tomato

    Directory of Open Access Journals (Sweden)

    Dursun KISA

    2017-12-01

    Full Text Available Plants maintain their life cycles under the various environmental conditions such as oxidative stress induced by heavy metals. Accumulation of metal ions in plants causes the formation of free radicals and stimulates the antioxidative defense systems. In this study, the activities of APX, POD, and SOD are investigated in the leaves and roots of tomato cultivated under the heavy metal-induced stress. The activities of APX, POD, and SOD exhibited remarkable induction with the treatment of Cd, Cu and Pb (10, 20 and 50 ppm in the leaves of tomato compared to control plants except for 50 ppm Pb. In roots, APX activity changed depending on the heavy metal types and concentrations, while Cd clearly increased it with stress conditions, but Cu decreased in tomato compared to control. The activity of POD clearly exhibited that the all doses of heavy metals reduced the enzyme activity in roots polluted with heavy metals. The treatment of Cd (10, 20 and 50 ppm significantly increased the activity of SOD, however, Cu showed the opposite effect which significantly decreased with increasing doses in roots compared to uncontaminated plants. Also, roots from plants grown on the high concentration of Pb (20 and 50 ppm induced the activity of SOD. Briefly, it is clear responses which Cd significantly raised the activities of APX and SOD in leaves and roots of tomato. The decreases caused by these metals in the activity of POD and Cu in the activities of APX and SOD in roots of tomato can be clarified by the result of heavy metal-induced the over production of free radical.

  2. Impact-parameter dependence of the electromagnetic particle production in ultrarelativistic heavy-ion collisions

    International Nuclear Information System (INIS)

    Vidovic, M.; Greiner, M.; Best, C.; Soff, G.

    1992-08-01

    The cross section for the electromagentic production of different particles in heavy-ion collision is derived within the external field approach. The underlying assumption leading to the equivalent photon method is that the transverse components of the virtual photon momenta are small compared to their longitudinal components. Introducing polarized photon-fusion cross sections, it is possible to generalize the equivalent photon method to describe the impact- parameter dependence of the particle production. The impact- parameter dependent production of scalar and pseudoscalar (spin 0) bosons, charged (spin 0) boson pairs and fermion pairs is discussed in general. (orig.)

  3. Impact of the track structure of heavy charged particles on cytogenetic damage in human blood lymphocytes

    Science.gov (United States)

    Lee, Ryonfa; Nasonova, Elena; Sommer, Sylwetster; Hartel, Carola; Durante, Marco; Ritter, Sylvia

    In space, astronauts are unavoidably exposed to charged particles from protons to irons. For a better estimate of the health risks of astronauts, further knowledge on the biological effects of charged particles, in particular the induction of cytogenetic damage is required. One im-portant factor that determines the biological response is the track structure of particles, i.e. their microscopic dose deposition in cells. The aim of the present study was to assess the influence of track structure of heavy ions on the yield and the quality of cytogenetic damage in human peripheral blood lymphocytes representing normal tissue. Cells were irradiated with 9.5 MeV/u C-ions or 990 MeV/u Fe-ions which have a comparable LET (175 keV/µm and 155 keV/µm, respectively) but a different track radius (2.3 and 6200 µm, respectively). When aberrations were analyzed in first cycle metaphases collected at different post-irradiation times (48-84 h) following fluorescence plus Giemsa staining, an increase in the aberration yield with sampling time was observed for both radiation qualities reflecting a damage dependent cell cycle progression delay to mitosis. The pronounced differences in the aberration frequency per cell are attributable to the stochastic distribution of particle traversals per cell nucleus (radius: 2.8 µm). Following C-ion exposure we found a high fraction of non-aberrant cells in samples collected at 48 h which represent cells not directly hit by a particle and slightly damaged cells that successfully repaired the induced lesions. In addition, at higher C-ion fluences the aberra-tion yield saturated, suggesting that a fraction of lymphocytes receiving multiple particle hits is not able to reach mitosis. On the other hand, at 48 h after Fe-ion exposure the proportion of non-aberrant cells is lower than after C-ion irradiation clearly reflecting the track structure of high energy particles (i.e. more homogeneous dose deposition compared to low energy C

  4. Bibliography of atomic and molecular excitation in heavy particle collisions, 1950--1975

    International Nuclear Information System (INIS)

    Hawthorne, S.W.; Thomas, E.W.; Barnett, C.F.; Crandall, D.H.; Gilbody, H.B.; Kirkpatrick, M.I.; McDaniel, E.W.; Phaneuf, R.A.

    1979-02-01

    This annotated bibliography lists published work on atomic and molecular excitation in heavy particle collisions for the period 1950 to 1975. Sources include scientific journals, abstract compilations, conference proceedings, books, and reports. The bibliography is arranged alphabetically by author. Each entry indicates whether the work was experimental or theoretical, what energy range was covered, and what reactants were investigated. Following the bibliographical listing are indexes of reactions and authors

  5. Response of mouse skin and bone marrow to heavy charged particles

    International Nuclear Information System (INIS)

    Ainsworth, E.J.

    1980-01-01

    Because of the desirability to determine RBE at therapeutically relevant dose levels, our approach was to use a challenge-dose technique. This challenge-dose technique assesses injury accumulation and repair or recovery following administration of comparatively low doses by challenging animals. No previous studies have been conducted using CFU-S irradiated in vivo as a model system to assess the RBE of heavy charged particles for either cell killing or for late effects. The goal of the CFU-S studies reported here was to determine the RBE for cell killing, and to use these data to design experiments to explore the effects of HZE particle dose fractionation on femur CFU-S repopulation and on late effects indicated by a reduction in the size of the CFU-S compartment

  6. Beam instability during high-current heavy-ion beam transport

    International Nuclear Information System (INIS)

    Kikuchi, T.; Someya, T.; Kawata, S.; Nakajima, M.; Horioka, K.

    2005-01-01

    In driver system for heavy ion inertial fusion, beam dynamics is investigated by particle-in-cell simulations during final beam bunching. The particle simulations predict that the beam is transported with the localized transverse charge distribution induced by the strong space charge effect. The calculation results also show that the emittance growth during the longitudinal bunch compression for various particle distributions at the initial conditions and with two types of transverse focusing model, which are a continuous focusing and an alternating gradient focusing lattice configurations. (author)

  7. Nuclear research with heavy ions. Annual progress report, January 1, 1977--December 31, 1977

    International Nuclear Information System (INIS)

    Kaplan, M.

    1977-10-01

    The experimental research program consists of several interrelated parts: (1) Reactions of Very Heavy Ions with Complex Nuclei; (2) Studies of Compound Nucleus Reactions Induced by Heavy Ions; and (3) Recoil Studies of Heavy Ion Reactions. Using solid-state detector telescopes and gas-ionization detector telescopes we have studied the emission of 1 H, 2 H, 3 H, 4 He and heavy fragments from the reactions of 720 MeV 86 Kr with 197 Au. Coincidence measurements between light charged particles and a heavy fragment indicate that most of the observed 4 He particles are evaporated by equilibrated Kr*-like and Au*-like excited products from deep inelastic reactions, but a significant number of preequilibrium 4 He particles seem to be emitted in directions normal to the separating fragments. Studies of angular correlations between two heavy fragments provide strong evidence for sequential fission of the Au*-like reaction fragments, and the probability of this process has been estimated as a function of Q, the energy damping in the primary collision. Parallel studies of charged particle emission, fission, and evaporation residues in compound nucleus reactions map out the de-excitation characteristics of highly excited heavy nuclei as functions of E* and J. Results are presented for the compound nucleus 194 Hg formed at matched excitation energies via different entrance channels

  8. A review on recent light particle correlation data from heavy ion collisions at intermediate and low energies

    International Nuclear Information System (INIS)

    Ardouin, D.

    1996-01-01

    A review of recent two-particle interferometry data for heavy-ion collisions in the domain of energy between ten and a few hundreds of MeV/nucleon is presented. Not only identical particles but unlike particle correlations have been used successfully as a probe for space-time dynamics of the collision process. Due to the availability of new dedicated charged particles or photon multi-detectors, the field of particle interferometry is moving to a good level of quantitative description: excitation energy and impact parameter dependences are now provided which should stimulate additional theoretical calculations for two-particle cross sections and emission of light fragments. (author)

  9. Direct Observation of Heavy-Tailed Storage Times of Bed Load Tracer Particles Causing Anomalous Superdiffusion

    Science.gov (United States)

    Bradley, D. Nathan

    2017-12-01

    A consensus has formed that the step length distribution of fluvial bed load is thin tailed and that the observed anomalous superdiffusion of bed load tracer particles must arise from heavy-tailed resting times. However, heavy-tailed resting times have never been directly observed in the field over multiple floods. Using 9 years of data from a large bed load tracer experiment, I show that the spatial variance of the tracer plume scales faster than linearly with integrated excess stream power, indicating anomalous superdiffusion. The superdiffusion is caused by a heavy-tailed distribution of observed storage times that is fit with a truncated Pareto distribution with a tail parameter that is predicted by anomalous diffusion theory. The heavy-tailed distribution of storage times causes the tracer virtual velocity to slow over time, indicated by a sublinear increase in the mean displacement that is predicted by the storage time distribution tail parameter.

  10. Activation cross-section data for -particle-induced nuclear reactions ...

    Indian Academy of Sciences (India)

    B M ALI

    2018-02-20

    particle-induced nuclear reactions on natural vanadium up to 20 MeV. It should be mentioned that this study represents a part of (a supplement) systematical study of charged particles-induced nuclear reactions. Earlier studies were.

  11. Heavy metal and abiotic stress inducible metallothionein isoforms from Prosopis juliflora (SW) D.C. show differences in binding to heavy metals in vitro.

    Science.gov (United States)

    Usha, B; Venkataraman, Gayatri; Parida, Ajay

    2009-01-01

    Prosopis juliflora is a tree species that grows well in heavy metal laden industrial sites and accumulates heavy metals. To understand the possible contribution of metallothioneins (MTs) in heavy metal accumulation in P. juliflora, we isolated and compared the metal binding ability of three different types of MTs (PjMT1-3). Glutathione S-transferase fusions of PjMTs (GSTMT1-3) were purified from Escherichia coli cells grown in the presence of 0.3 mM cadmium, copper or zinc. Analysis of metal bound fusion proteins using atomic absorption spectrometry showed that PjMT1 bound higher levels of all three heavy metals as compared to PjMT2 and PjMT3. A comparative analysis of the genomic regions (including promoter for all three PjMTs) is also presented. All three PjMTs are induced by H(2)O(2) and ABA applications. PjMT1 and PjMT2 are induced by copper and zinc respectively while PjMT3 is induced by copper, zinc and cadmium. Variation in induction of PjMTs in response to metal exposure and their differential binding to metals suggests that each MT has a specific role in P. juliflora. Of the three MTs analyzed, PjMT1 shows maximum heavy metal sequestration and is thus a potential candidate for use in heavy metal phytoremediation.

  12. Heavy metal-induced cytotoxicity to cultured human epidermal keratinocytes and effects of antioxidants.

    Science.gov (United States)

    Kappus, H; Reinhold, C

    1994-04-01

    Human epidermal keratinocytes which have been cultured were treated with the heavy metal ions of cadmium, mercury, copper and zinc. Cytotoxicity was measured either by protein estimation or by using the neutral red assay. Antioxidants were added in order to find out whether heavy metal-induced cytotoxicity is related to oxidative stress. All metals used showed considerable cytotoxic effects within 24 h in moderate concentrations. None of the antioxidants vitamin E (alpha-tocopherol), pyrogallol, propyl gallate, BHT or ebselen showed any protective or preventive effect. This indicates that oxidative stress may not be involved in the cytotoxicity induced by heavy metals in human epidermal keratinocytes. The cells used are, however, a valuable tool to study mechanisms of cytotoxicity.

  13. Strange Particles and Heavy Ion Physics

    Energy Technology Data Exchange (ETDEWEB)

    Bassalleck, Bernd [Univ. of New Mexico, Albuquerque, NM (United States). Dept. of Physics and Astronomy; Fields, Douglas [Univ. of New Mexico, Albuquerque, NM (United States). Dept. of Physics and Astronomy

    2016-04-28

    This very long-running grant has supported many experiments in nuclear and particle physics by a group from the University of New Mexico. The gamut of these experiments runs from many aspects of Strangeness Nuclear Physics, to rare Kaon decays, to searches for exotic Hadrons such as Pentaquark or H-Dibaryon, and finally to Spin Physics within the PHENIX collaboration at RHIC. These experiments were performed at a number of laboratories worldwide: first and foremost at Brookhaven National Lab (BNL), but also at CERN, KEK, and most recently at J-PARC. In this Final Technical Report we summarize progress and achievements for this award since our last Progress Report, i.e. for the period of fall 2013 until the award’s termination on November 30, 2015. The report consists of two parts, representing our two most recent experimental efforts, participation in the Nucleon Spin Physics program of the PHENIX experiment at RHIC, the Relativistic Heavy Ion Collider at BNL – Task 1, led by Douglas Fields; and participation in several Strangeness Nuclear Physics experiments at J-PARC, the Japan Proton Accelerator Research Center in Tokai-mura, Japan – Task 2, led by Bernd Bassalleck.

  14. Charged particle yields and spectra in p+p and Heavy Ion Collisions with ATLAS at the LHC

    CERN Document Server

    Dolejší, J; The ATLAS collaboration

    2010-01-01

    The ATLAS experiment has extensive charged particle tracking over full azimuth and within |eta|<2.5. The spectrometer consists of three pixel layers and four double-layer strip layers, giving 11 space points in all. The existing tracking software used for proton-proton collisions has been optimized for the high-multiplicity heavy ion environment. Extensions of the existing tracking to lower pT (100 MeV) using tracks and pixel tracklets, work underway for p+p, will be discussed in the context of heavy ion collisions. Finally, by correlating high momentum tracks with the ATLAS calorimetry, fake tracks can also be rejected at very high pT. The physics performance of the ATLAS inner detector for dN/deta, inclusive particle spectra, and two-particle correlations (in delta-eta and delta-phi) will be discussed. The tracking performance within jets, which is essential for the measurement of jet fragmentation functions, will also be presented.

  15. Geraniin suppresses RANKL-induced osteoclastogenesis in vitro and ameliorates wear particle-induced osteolysis in mouse model

    Energy Technology Data Exchange (ETDEWEB)

    Xiao, Fei; Zhai, Zanjing; Jiang, Chuan; Liu, Xuqiang; Li, Haowei; Qu, Xinhua [Department of Orthopedics, Shanghai Key Laboratory of Orthopedic Implant, Shanghai Ninth People' s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai (China); Ouyang, Zhengxiao [Department of Orthopedics, Shanghai Key Laboratory of Orthopedic Implant, Shanghai Ninth People' s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai (China); Department of Orthopaedics, Hunan Provincial Tumor Hospital and Tumor Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan 410013 (China); Fan, Qiming; Tang, Tingting [Department of Orthopedics, Shanghai Key Laboratory of Orthopedic Implant, Shanghai Ninth People' s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai (China); Qin, An, E-mail: dr.qinan@gmail.com [Department of Orthopedics, Shanghai Key Laboratory of Orthopedic Implant, Shanghai Ninth People' s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai (China); Gu, Dongyun, E-mail: dongyungu@gmail.com [Department of Orthopedics, Shanghai Key Laboratory of Orthopedic Implant, Shanghai Ninth People' s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai (China); Engineering Research Center of Digital Medicine and Clinical Translation, Ministry of Education of PR China (China); School of Biomedical Engineering, Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030 (China)

    2015-01-01

    Wear particle-induced osteolysis and subsequent aseptic loosening remains the most common complication that limits the longevity of prostheses. Wear particle-induced osteoclastogenesis is known to be responsible for extensive bone erosion that leads to prosthesis failure. Thus, inhibition of osteoclastic bone resorption may serve as a therapeutic strategy for the treatment of wear particle induced osteolysis. In this study, we demonstrated for the first time that geraniin, an active natural compound derived from Geranium thunbergii, ameliorated particle-induced osteolysis in a Ti particle-induced mouse calvaria model in vivo. We also investigated the mechanism by which geraniin exerts inhibitory effects on osteoclasts. Geraniin inhibited RANKL-induced osteoclastogenesis in a dose-dependent manner, evidenced by reduced osteoclast formation and suppressed osteoclast specific gene expression. Specially, geraniin inhibited actin ring formation and bone resorption in vitro. Further molecular investigation demonstrated geraniin impaired osteoclast differentiation via the inhibition of the RANKL-induced NF-κB and ERK signaling pathways, as well as suppressed the expression of key osteoclast transcriptional factors NFATc1 and c-Fos. Collectively, our data suggested that geraniin exerts inhibitory effects on osteoclast differentiation in vitro and suppresses Ti particle-induced osteolysis in vivo. Geraniin is therefore a potential natural compound for the treatment of wear particle induced osteolysis in prostheses failure. - Highlights: • Geraniin suppresses osteoclasts formation and function in vitro. • Geraniin impairs RANKL-induced nuclear factor-κB and ERK signaling pathway. • Geraniin suppresses osteolysis in vivo. • Geraniin may be used for treating osteoclast related diseases.

  16. Synergistic effects in radiation-induced particle ejection from solid surfaces

    International Nuclear Information System (INIS)

    Itoh, Noriaki

    1990-01-01

    A description is given on radiation-induced particle ejection from solid surfaces, emphasizing synergistic effects arising from multi-species particle irradiation and from irradiation under complex environments. First, it is pointed out that synergisms can be treated by introducing the effects of material modification on radiation-induced particle ejection. As examples of the effects of surface modification on the sputtering induced by elastic encounters, sputtering of alloys and chemical sputtering of graphite are briefly discussed. Then the particle ejection induced by electronic encounters is explained emphasizing the difference in the behaviors from materials to materials. The possible synergistic effects of electronic and elastic encounters are also described. Lastly, we point out the importance of understanding the elementary processes of material-particle interaction and of developing computer codes describing material behaviors under irradiation. (author)

  17. Effect of Turbulence Internal Structure on Diffusion of Heavy Inertial Particles

    Directory of Open Access Journals (Sweden)

    I. V. Derevich

    2015-01-01

    Full Text Available Based on the spectral expansion of Euler correlation of the carrier medium the a closed system of functional equations for the Lagrange spectra of heavy inertial particles and the velocity fluctuations of the carrier medium on the particle trajectory have been obtained. To split the fourth moments the approximation of quasinormality and velocity fluctuations of particles is performed by a random Gaussian process. The approximate self-consistent method is proposed for solving the resulting system of functional equations. The influence of the particle inertia, the velocity of the averaged slip and microstructure of velocity fluctuations of the medium on the parameters of the chaotic motion of an impurity has been studied. It is shown that the difference in integral time scales of Eulerian and Lagrangian correlations is associated with the spatial microstructure of velocity fluctuations of the medium. It is established that in the absence of mass forces, the coefficient of the stationary diffusion of inertial particles is always greater than the diffusion coefficient of inertialess impurity. The dependence of the turbulent diffusion coefficient of particles impurity on the structural parameter of turbulence has been illustrated. The spectrum of Euler correlations of medium velocity fluctuations is modeled by Karman distributions. The influence of the particle inertia, the velocity of the averaged slip and microstructure of velocity fluctuations of the medium on the parameters of the chaotic motion of an impurity has been studied. It is shown that the difference in integral time scales of Eulerian and Lagrangian correlations is associated with the spatial microstructure of velocity fluctuations of the medium. It is established that in the absence of mass forces, the coefficient of the stationary diffusion of inertial particles is always larger than the diffusion coefficient of inertialess impurity. The dependence of the turbulent diffusion

  18. Transport of intense particle beams with application to heavy ion fusion

    International Nuclear Information System (INIS)

    Buchanan, H.L.; Chambers, F.W.; Lee, E.P.; Yu, S.S.; Briggs, R.J.; Rosenbluth, M.N.

    1979-01-01

    An attractive feature of the high energy (> GeV) heavy ion beam approach to inertial fusion, as compared with other particle beam systems, is the relative simplicity involved in the transport and focusing of energy on the target inside a reactor chamber. While this focusing could be done in vacuum by conventional methods with multiple beams, there are significant advantages in reactor design if one can operate at gas pressures around one torr. In this paper we summarize the results of our studies of heavy ion beam transport in gases. With good enough charge and current neutralization, one could get a ballistically-converging beam envelope down to a few millimeters over a 10 meter path inside the chamber. Problems of beam filamentation place important restrictions on this approach. We also discuss transport in a self-focused mode, where a relatively stable pressure window is predicted similar to the observed window for electron beam transport

  19. Effects of heavy particle irradiation on central nervous system

    International Nuclear Information System (INIS)

    Nojima, Kumie; Liu Cuihua; Nagaoka, Shunji

    2003-01-01

    Effects of low dose heavy particle radiation to central nervous system were studied using mouse neonatal brain cells in culture exposed to heavy ions and X ray at fifth days of the culture. The subsequent biological effects were evaluated by an induction of apoptosis and the survivability of neurons focusing on the dependencies of the animal strains with different genetic types, and linear energy transfer (LET) of the different nucleons. Of the three mouse strains tested, severe combined immunodeficiency (SCID), B6 and C3H, used for brain cell culture, SCID was the most sensitive and C3H the least sensitive to both X-ray and carbon ion (290 MeV/n) when compared by 10% apoptotic induction. The LET dependency was compared with using SCID cells exposing to different ions, (X, C, Si, Ar, and Fe). Although no detectable LET dependency was observed at higher dose than 1 Gy, an enhancement was observed in the high LET region and at lower dose than 0.5 Gy. The survivability profiles of the neurons were different in the mouse strains and ions. Memory and learning function of adult mice were studied using water maze test after localized carbon- or iron-ion irradiation to hippocampus area. (author)

  20. Particle size distribution and characteristics of heavy metals in road-deposited sediments from Beijing Olympic Park.

    Science.gov (United States)

    Li, Haiyan; Shi, Anbang; Zhang, Xiaoran

    2015-06-01

    Due to rapid urbanization and industrialization, heavy metals in road-deposited sediments (RDSs) of parks are emitted into the terrestrial, atmospheric, and water environment, and have a severe impact on residents' and tourists' health. To identify the distribution and characteristic of heavy metals in RDS and to assess the road environmental quality in Chinese parks, samples were collected from Beijing Olympic Park in the present study. The results indicated that particles with small grain size (Pb>Cu>Zn. This study analyzed the mobility of heavy metals in sediments using partial sequential extraction with the Tessier procedure. The results revealed that the apparent mobility and potential metal bioavailability of heavy metals in the sediments, based on the exchangeable and carbonate fractions, decreased in the order: Cd>Zn≈Pb>Cu. Copyright © 2015. Published by Elsevier B.V.

  1. Search for heavy resonances in two-particle final states with leptons, jets and photons at CMS

    CERN Document Server

    Gueth, Andreas

    2014-01-01

    At the LHC, the production of heavy resonances decaying into a pair of particles can be probed at unprecedented centre-of-mass energies. Two-particle resonances are predicted in a variety of BSM models and can be searched for in a largely model-independent fashion. Results from searches for resonances in final states with leptons, jets and photons based on the full dataset of 20/fb taken by the CMS detector in 2012 in proton-proton collisions at a centre-of-mass energy of 8 TeV are presented. They are interpreted in terms of various theories of BSM physics ranging from generic heavy resonances such as the Z' to excited quarks or Randall-Sundrum gravitons. In the absence of a significant deviation from the expected SM background 95\\% CL limits are set on model parameters of the theories under study.

  2. Nuclear research with heavy ions. Annual progress report, January 1, 1979-December 31, 1979

    International Nuclear Information System (INIS)

    Kaplan, M.

    1979-10-01

    The experimental research emphasizes the detection and measurement of light charged particles emitted in reactions between heavy ions and complex nuclei. The program involves a collaboration between Carnegie-Mellon University and SUNY at Stony Brook, and utilizes the SuperHILAC and 88'' cyclotron accelerator facilities of the Lawrence Berkeley Laboratory. Correlations between light charged particles and heavy fragments provide detailed insights into the dynamics of the reaction mechanism. The light charged particles evaporated from fully accelerated fragments yield information on the excitation energies and spins of the equilibrated reaction products, whereas those particles that are emitted prior to thermal equilibration give a view of the early stages of the reaction. Experimental results of fusion and charged particle emission cross sections are discussed for a variety of heavy ion reactions, particularly those induced by 40 Ar ions. The theoretical development of the statistical model as applied to particle evaporation is reviewed, and semiempirical methods for facilitating comparisons with experimental data are presented. Current results from singles and coincidence experiments are given in detail for reactions of 340-MeV 40 Ar with Au, and analyses of average spins and energy sharing among particles are discussed

  3. Swift heavy ion induced modification of aliphatic polymers

    International Nuclear Information System (INIS)

    Hossain, Umme Habiba

    2015-01-01

    In this thesis, the high energy heavy ion induced modification of aliphatic polymers is studied. Two polymer groups, namely polyvinyl polymers (PVF, PVAc, PVA and PMMA) and fluoropolymers (PVDF, ETFE, PFA and FEP) were used in this work. Polyvinyl polymers were investigated since they will be used as insulating materials in the superconducting magnets of the new ion accelerators of the planned International Facility for Antiproton and Ion Research (FAIR) at the GSI Helmholtz-Centre of Heavy Ion Research (GSI) in Darmstadt. In order to study ion-beam induced degradation, all polymer foils were irradiated at the GSI linear accelerator UNILAC using several projectiles (U, Au, Sm, Xe) and experimentation sites (beam lines X0 and M3) over a large fluence regime (1 x 10 10 - 5 x 10 12 ions/cm 2 ). Five independent techniques, namely infrared (FT-IR) and ultraviolet-visible (UV-Vis) spectroscopy, residual gas analysis (RGA), thermal gravimetric analysis (TGA), and mass loss analysis (ML), were used to analyze the irradiated samples. FT-IR spectroscopy revealed that ion irradiation led to the decrease of characteristic band intensities showing the general degradation of the polymers, with scission of side groups and the main backbone. As a consequence of the structural modification, new bands appeared. UV-Vis transmission analysis showed an absorption edge shift from the ultraviolet region towards the visible region indicating double bond and conjugated double bond formation. On-line massspectrometric residual gas analysis showed the release of small gaseous fragment molecules. TGA analysis gave evidence of a changed thermal stability. With ML analysis, the considerable mass loss was quantified. The results of the five complementary analytical methods show how heavy ion irradiation changes the molecular structure of the polymers. Molecular degradation mechanisms are postulated. The amount of radiation damage is found to be sensitive to the used type of ionic species. While

  4. Closed form formula for the exchange integrals in the impact-parameter treatment of heavy-particle collisions

    International Nuclear Information System (INIS)

    Kocbach, Ladislav; Liska, Richard

    1994-01-01

    The three-dimensional exchange integrals in the impact-parameter treatment of heavy particle collisions can be transformed to one-dimensional integrals over finite range. The closed form formula for the integrands of these one-dimensional integrals is derived. (Author)

  5. A BGO detector array and its application in intermediate energy heavy ion experiments

    International Nuclear Information System (INIS)

    Li Zuyu; Jin Genming; He Zhiyong; Duan Limin; Wu Heyu; Qi Yujin; Luo Qingzheng; Zhang Baoguo; Wen Wanxin; Dai Guangxi

    1996-01-01

    A BGO crystal (Bi 4 Ge 3 O 12 ) as the E detector of ΔE-E for identification of reaction products has been used for detecting the charged particles emitting from the 25 MeV 40 Ar induced reaction. The responses of the BGO crystal to various light charged particles were measured. A close-packed hexagonal array consisting of thirteen ΔE-E telescopes (Si-BGO) has been developed to detect the light charged particles interfering with each other in intermediate-energy heavy-ion induced reactions. Some applications of this telescope array are also described. (orig.)

  6. Multifragmentation in intermediate energy 129Xe-induced heavy-ion reactions

    Energy Technology Data Exchange (ETDEWEB)

    Tso, Kin [Univ. of California, Berkeley, CA (United States)

    1996-05-01

    The 129Xe-induced reactions on natCu, 89Y, 165Ho, and 197Au at bombarding energies of E/A = 40 & 60 MeV have been studied theoretically and experimentally in order to establish the underlying mechanism of multifragmentation at intermediate energy heavy-Ion collisions. Nuclear disks formed in central heavy-ion collisions, as simulated by means of Boltzmann-like kinetic equations, break up into several fragments due to a new kind of Rayleigh-like surface instability. A sheet of liquid, stable in the limit of non-interacting surfaces, is shown to become unstable due to surface-surface interactions. The onset of this instability is determined analytically. A thin bubble behaves like a sheet and is susceptible to the surface instability through the crispation mode. The Coulomb effects associated with the depletion of charges in the central cavity of nuclear bubbles are investigated. The onset of Coulomb instability is demonstrated for perturbations of the radial mode. Experimental intermediate-mass-fragment multiplicity distributions for the 129Xe-induced reactions are shown to be binomial at each transverse energy. From these distributions, independent of the specific target, an elementary binary decay probability p can be extracted that has a thermal dependence. Thus it is inferred that multifragmentation is reducible to a combination of nearly independent emission processes. If sequential decay is assumed, the increase of p with transverse energy implies a contraction of the emission time scale. The sensitivity of p to the lower Z threshold in the definition of intermediate-mass-fragments points to a physical Poisson simulations of the particle multiplicities show that the weak auto-correlation between the fragment multiplicity and the transverse energy does not distort a Poisson distribution into a binomial distribution. The effect of device efficiency on the experimental results has also been studied.

  7. A new formulation of the effective theory for heavy particles

    International Nuclear Information System (INIS)

    Aglietti, U.; Capitani, S.

    1994-01-01

    We derive the effective theories for heavy particles with a functional integral approach by integrating away the states with high velocity and with high virtuality. This formulation is non-perturbative and has a close connection with the Wilson renormalization group transformation. The fixed point hamiltonian of our transformation coincides with the static hamiltonian and irrelevant operators can be identified with the usual 1/M corrections to the static theory. No matching condition has to be imposed between the full and the static theory operators with our approach. The values of the matching constants come out as a dynamical effect of the renormalization group flow. ((orig.))

  8. Characterization of radiation damage induced by swift heavy ions in graphite

    Energy Technology Data Exchange (ETDEWEB)

    Hubert, Christian

    2016-05-15

    Graphite is a classical material in neutron radiation environments, being widely used in nuclear reactors and power plants as a moderator. For high energy particle accelerators, graphite provides ideal material properties because of the low Z of carbon and its corresponding low stopping power, thus when ion projectiles interact with graphite is the energy deposition rather low. This work aims to improve the understanding of how the irradiation with swift heavy ions (SHI) of kinetic energies in the range of MeV to GeV affects the structure of graphite and other carbon-based materials. Special focus of this project is given to beam induced changes of thermo-mechanical properties. For this purpose the Highly oriented pyrolytic graphite (HOPG) and glassy carbon (GC) (both serving as model materials), isotropic high density polycrystalline graphite (PG) and other carbon based materials like carbon fiber carbon composites (CFC), chemically expanded graphite (FG) and molybdenum carbide enhanced graphite composites (MoC) were exposed to different ions ranging from {sup 131}Xe to {sup 238}U provided by the UNILAC accelerator at GSI in Darmstadt, Germany. To investigate structural changes, various in-situ and off-line measurements were performed including Raman spectroscopy, x-ray diffraction and x-ray photo-electron spectroscopy. Thermo-mechanical properties were investigated using the laser-flash-analysis method, differential scanning calorimetry, micro/nano-indentation and 4-point electrical resistivity measurements. Beam induced stresses were investigated using profilometry. Obtained results provided clear evidence that ion beam-induced radiation damage leads to structural changes and degradation of thermal, mechanical and electrical properties of graphite. PG transforms towards a disordered sp2 structure, comparable to GC at high fluences. Irradiation-induced embrittlement is strongly reducing the lifetime of most high-dose exposed accelerator components. For

  9. Pre-equilibrium (exciton) model and the heavy-ion reactions with cluster emission

    CERN Document Server

    Betak, E

    2015-01-01

    We bring the possibility to include the cluster emission into the statistical pre-equilibrium (exciton) model enlarged for considering also the heavy ion collisions. At this moment, the calculations have been done without treatment of angular momentum variables, but all the approach can be straightforwardly applied to heavy-ion reactions with cluster emission including the angular momentum variables. The direct motivation of this paper is a possibility of producing the superdeformed nuclei, which are easier to be detected in heavy-ion reactions than in those induced by light projectiles (nucleons, deuterons, $\\alpha$-particles).

  10. Scaling theory of tunneling diffusion of a heavy particle interacting with phonons

    Science.gov (United States)

    Itai, K.

    1988-05-01

    The author discusses motion of a heavy particle in a d-dimensional lattice interacting with phonons by different couplings. The models discussed are characterized by the dimension (d) and the set of two indices (λ,ν) which specify the momentum dependence of the dispersion of phonon energy (ω~kν) and of the particle-phonon coupling (~kλ). Scaling equations are derived by eliminating the short-time behavior in a renormalization-group scheme using Feynman's path-integral method, and the technique developed by Anderson, Yuval, and Hamann for the Kondo problem. The scaling equations show that the particle is localized in the strict sense when (2λ+d+2)/ν2. In the marginal case, i.e., (2λ+d+2)/ν=2, localization occurs for couplings larger than a critical value. This marginal case shows Ohmic dissipation and is a close analogy to the Caldeira-Leggett model for macroscopic quantum tunneling and the hopping models of Schmid's type. For large-enough (2λ+d+2)/ν, the particle is considered practically localized, but the origin of the localization is quite different from that for (2λ+d+2)/ν<=2. .AE

  11. Relative biological effectiveness of protons and heavy particles

    International Nuclear Information System (INIS)

    Vyglenov, A.; Fedorenko, B.; Kabachenko, A.

    1986-01-01

    The genetic effectiveness was studied of protons (9 GeB/nuclon, 0,72 Gy/min), α-particles (4 GeB/nuclon, 0,9 Gy/min) and carbon ions (4 GeB/nuclon 0,36 Gy/min). The translocation yield in mouse spermatogonia was used as indicator of radiation-induced genetic injury. Reciprocal translocation were registered six months after the irradiation on spermatocytes in diakinesmetaphase I. Comparison was made with gamma-irradiated animals from 60 Co source with dose rate 1,44 Gy/min. The relative biological effectiveness (RBE) was determined by comparing the regression coefficients from the linear dose translocation yield dependency. The values of the RBE coefficients were 0.8, 0.9 and 1.2, accordingly for protons, α-particles and carbon ions

  12. Monte Carlo simulation of particle-induced bit upsets

    Science.gov (United States)

    Wrobel, Frédéric; Touboul, Antoine; Vaillé, Jean-Roch; Boch, Jérôme; Saigné, Frédéric

    2017-09-01

    We investigate the issue of radiation-induced failures in electronic devices by developing a Monte Carlo tool called MC-Oracle. It is able to transport the particles in device, to calculate the energy deposited in the sensitive region of the device and to calculate the transient current induced by the primary particle and the secondary particles produced during nuclear reactions. We compare our simulation results with SRAM experiments irradiated with neutrons, protons and ions. The agreement is very good and shows that it is possible to predict the soft error rate (SER) for a given device in a given environment.

  13. Monte Carlo simulation of particle-induced bit upsets

    Directory of Open Access Journals (Sweden)

    Wrobel Frédéric

    2017-01-01

    Full Text Available We investigate the issue of radiation-induced failures in electronic devices by developing a Monte Carlo tool called MC-Oracle. It is able to transport the particles in device, to calculate the energy deposited in the sensitive region of the device and to calculate the transient current induced by the primary particle and the secondary particles produced during nuclear reactions. We compare our simulation results with SRAM experiments irradiated with neutrons, protons and ions. The agreement is very good and shows that it is possible to predict the soft error rate (SER for a given device in a given environment.

  14. Light particle and gamma ray emission measurements in heavy ion reactions. Progress report

    International Nuclear Information System (INIS)

    Petitt, G.A.

    1983-01-01

    Studies of neutron and charged particle emission in heavy ion reactions using the facilities at the HHIRF and the new computer facilities at Georgia State are briefly described. A progress report for 1982 to 1983 is combined with a proposal for work to be performed during 1983 to 1984. Present activities and immediate plans for a run already approved by the Program Advisory Committee of the HHIRF are discussed

  15. On-line mass spectometry of nuclear reactions induced by heavy ions

    International Nuclear Information System (INIS)

    Saint Simon, M. de.

    1977-01-01

    The adaptation of the on-line mass-spectrometric technique to the special conditions of heavy ion induced reactions is described. The method is very selective about A and Z, even for the very heavy reaction products in counterpart of the limitation of its applications to the alkaline elements only. This method is used in order to study the effects of angular momentum brought by the projectile in the complete fusion process and in the following neutron evaporation. The analysis of excitation functions shows that the increase in mass of the projectile has not always the effect of increasing the rotation energy of the compound nucleus. The on-line mass spectrometry has allowed to study heavy ion induced fission. Measurements of complementary isotopic distributions of fission products make it possible to explain that the total number of neutrons emitted per fission can be always deduced from the fragment excitation energy. The study of the isotope distribution variance shows that the statistical model for fission is in good agreement with experimental results after taking into account the non-fusion processes [fr

  16. Charged particle induced delayed X-rays (DEX) for the analysis of intermediate and heavy elements

    Science.gov (United States)

    Pillay, A. E.; Erasmus, C. S.; Andeweg, A. H.; Sellschop, J. P. F.; Annegarn, H. J.; Dunn, J.

    1988-12-01

    The emission of K X-rays from proton-rich and metastable radionuclides, following proton activation of the stable isotopes of the elements of interest, has not been widely used as a means of analysis. The thrust of this paper proposes a nuclear technique using delayed X-rays for the analysis of low concentrations of intermediate and heavy elements. The method is similar to the delayed gamma-ray technique. Proton bombardment induces mainly (p, n) reactions whereas the delayed X-rays originate largely from e --capture and isomeric transition. Samples of rare earth and platinum group elements (PGE), in the form of compacted powders, were irradiated with an 11 MeV proton beam and delayed X-rays detected with a 100 mm 2 Ge detector. Single element spectra for a range of rare earths and PGEs are presented. Analytical conditions are demonstrated for Pd in the range 0.1-5%. Spectra from actual geological samples of a PGE ore, preconcentrated by fire-assay, and monazite are presented. All six platinum group elements are visible and interference-free in a single spectrum, a marked advance on other nuclear techniques for these elements, including PIXE and neutron activation analysis (NAA).

  17. Cell and tissue kinetics of the subependymal layer in mouse brain following heavy charged particle irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Manley, N.B.; Fabrikant, J.I.; Alpen, E.L.

    1988-12-01

    The following studies investigate the cellular response and cell population kinetics of the subependymal layer in the mouse brain exposed to heavy charged particle irradiation. Partial brain irradiation with helium and neon ions was confined to one cortex of the brain. Both the irradiated and the unirradiated contralateral cortex showed similar disturbances of the cell and tissue kinetics in the subependymal layers. The irradiated hemisphere exhibited histological damage, whereas the unirradiated side appeared normal histologically. This study concerns the cell population and cell cycle kinetics of the subependymal layer in the mouse brain, and the effects of charged particle irradiations on this cell population. Quantitative high resolution autoradiography was used to study the kinetic parameters in this cell layer. This study should help in understanding the effects of these high-energy heavy ions on normal mammalian brain tissue. The response of the mammalian brain exposure to charged particle ionizing radiation may be extremely variable. It varies from minimal physiological changes to overt tissue necrosis depending on a number of factors such as: the administered dose, dose-rate, the volume of the irradiated tissue, and the biological end-point being examined.

  18. Study of transient current induced by heavy-ion microbeams in Si and GaAs

    Energy Technology Data Exchange (ETDEWEB)

    Hirao, Toshio; Nashiyama, Isamu; Kamiya, Tomihiro; Suda, Tamotu [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment

    1997-03-01

    Heavy-ion microbeams were applied to the study of mechanism of single event upset (SEU). Transient current induced in p{sup +}n junction diodes by strike of heavy ion microbeam were measured by using a high-speed digitizing sampling system. (author)

  19. Transverse energy per charged particle in heavy-ion collisions: Role of collective flow

    Science.gov (United States)

    Kumar Tiwari, Swatantra; Sahoo, Raghunath

    2018-03-01

    The ratio of (pseudo)rapidity density of transverse energy and the (pseudo)rapidity density of charged particles, which is a measure of the mean transverse energy per particle, is an important observable in high energy heavy-ion collisions. This ratio reveals information about the mechanism of particle production and the freeze-out criteria. Its collision energy and centrality dependence is almost similar to the chemical freeze-out temperature until top Relativistic Heavy-Ion Collider (RHIC) energy. The Large Hadron Collider (LHC) measurement at √{s_{NN}} = 2.76 TeV brings up new challenges towards understanding the phenomena like gluon saturation and role of collective flow, etc. being prevalent at high energies, which could contribute to the above observable. Statistical Hadron Gas Model (SHGM) with a static fireball approximation has been successful in describing both the centrality and energy dependence until top RHIC energies. However, the SHGM predictions for higher energies lie well below the LHC data. In order to understand this, we have incorporated collective flow in an excluded-volume SHGM (EV-SHGM). Our studies suggest that the collective flow plays an important role in describing E T/ N ch and it could be one of the possible parameters to explain the rise observed in E T/ N ch from RHIC to LHC energies. Predictions are made for E T/ N ch , participant pair normalized-transverse energy per unit rapidity and the Bjorken energy density for Pb+Pb collisions at √{s_{NN}} = 5.02 TeV at the Large Hadron Collider.

  20. Selective population of high-j states via heavy-ion-induced transfer reactions

    International Nuclear Information System (INIS)

    Bond, P.D.

    1982-01-01

    One of the early hopes of heavy-ion-induced transfer reactions was to populate states not seen easily or at all by other means. To date, however, I believe it is fair to say that spectroscopic studies of previously unknown states have had, at best, limited success. Despite the early demonstration of selectivity with cluster transfer to high-lying states in light nuclei, the study of heavy-ion-induced transfer reactions has emphasized the reaction mechanism. The value of using two of these reactions for spectroscopy of high spin states is demonstrated: 143 Nd( 16 O, 15 O) 144 Nd and 170 Er( 16 O, 15 Oγ) 171 Er

  1. Composition variations of low energy heavy ions during large solar energetic particle events

    Energy Technology Data Exchange (ETDEWEB)

    Ho, George C., E-mail: George.Ho@jhuapl.edu; Mason, Glenn M., E-mail: Glenn.Mason@jhuapl.edu [Johns Hopkins University Applied Physics Laboratory, Laurel, MD 20723 (United States)

    2016-03-25

    The time-intensity profile of large solar energetic particle (SEP) event is well organized by solar longitude as observed at Earth orbit. This is mostly due to different magnetic connection to the shock that is associated with large SEP event propagates from the Sun to the heliosphere. Earlier studies have shown event averaged heavy ion abundance ratios can also vary as a function of solar longitude. It was found that the Fe/O ratio for high energy particle (>10 MeV/nucleon) is higher for those western magnetically well connected events compare to the eastern events as observed at L1 by the Advanced Composition Explorer (ACE) spacecraft. In this paper, we examined the low energy (∼1 MeV/nucleon) heavy ions in 110 isolated SEP events from 2009 to the end of 2014. In addition, the optical and radio signatures for all of our events are identified and when data are available we also located the associated coronal mass ejection (CME) data. Our survey shows a higher Fe/O ratio at events in the well-connected region, while there are no corrections between the event averaged elemental composition with the associated coronal mass ejection speed. This is inconsistent with the higher energy results, but inline with other recent low-energy measurements.

  2. Inflaton decay and heavy particle production with negative coupling

    International Nuclear Information System (INIS)

    Greene, B.R.; Prokopec, T.; Roos, T.G.

    1997-01-01

    We study the decay of the inflaton in a general Z 2 xZ 2 symmetric two scalar theory. Since the dynamics of the system is dominated by states with large occupation numbers which admit a semiclassical description, the decay can be studied by solving the classical equations of motion on the lattice. Of particular interest is the case when the cross coupling between the inflaton and the second scalar field is negative, which is naturally allowed in many realistic models. While the inflaton decays via parametric resonance in the positive coupling case we find that for negative coupling there is a new mechanism of particle production which we call negative coupling instability. Because of this new mechanism the variances of the fields grow significantly larger before the production is shut off by the back reaction of the created particles, which could have important consequences for symmetry restoration by nonthermal phase transitions. We also find that heavy particles are produced much more efficiently with negative coupling, which is of prime importance for GUT baryogenesis. Using a simple toy model for baryogenesis and the results of our lattice simulations we show that for natural values of the cross coupling enough 10 14 GeV bosons are created to produce a baryon to entropy ratio consistent with observation. This is to be contrasted with the situation for positive coupling, where the value of the cross coupling required to produce such massive particles is technically unnatural. In addition to our numerical results we obtain analytical estimates for the maximum variances of the fields in an expanding universe for all cases of interest: massive and massless inflaton, positive and negative cross coupling, with and without significant self-interactions for the second field. copyright 1997 The American Physical Society

  3. Electron-positron pair creation in heavy ion collisions

    International Nuclear Information System (INIS)

    Kienle, P.

    1987-08-01

    We review here the status of experiments to study the electron positron pair creation in heavy ion atom collisions at bombarding energies close to the Coulomb barrier. The disentanglement and characterisation of various sources of positrons observed in such collisions are described with a focus on the monoenergetic electron positron pairs observed. They seem to originate from the two-body decay of a family of neutral particles with masses of about 3 m e and life times in the range of 6x10 -14 s -10 s, produced by high Coulomb fields. First attempts were made to create these particles by resonant Bhabha scattering. First we present some experimental methods for high efficiency positron spectroscopy in heavy ion collisions. Then we describe the discovery of positron creation induced by strong time changing Coulomb fields. (orig./HSI)

  4. Differential Superiority of Heavy Charged-Particle Irradiation to X-Rays: Studies on Biological Effectiveness and Side Effect Mechanisms in Multicellular Tumor and Normal Tissue Models.

    Science.gov (United States)

    Walenta, Stefan; Mueller-Klieser, Wolfgang

    2016-01-01

    This review is focused on the radiobiology of carbon ions compared to X-rays using multicellular models of tumors and normal mucosa. The first part summarizes basic radiobiological effects, as observed in cancer cells. The second, more clinically oriented part of the review, deals with radiation-induced cell migration and mucositis. Multicellular spheroids from V79 hamster cells were irradiated with X-rays or carbon ions under ambient or restricted oxygen supply conditions. Reliable oxygen enhancement ratios could be derived to be 2.9, 2.8, and 1.4 for irradiation with photons, (12)C(+6) in the plateau region, and (12)C(+6) in the Bragg peak, respectively. Similarly, a relative biological effectiveness of 4.3 and 2.1 for ambient pO2 and hypoxia was obtained, respectively. The high effectiveness of carbon ions was reflected by an enhanced accumulation of cells in G2/M and a dose-dependent massive induction of apoptosis. These data clearly show that heavy charged particles are more efficient in sterilizing tumor cells than conventional irradiation even under hypoxic conditions. Clinically relevant doses (3 Gy) of X-rays induced an increase in migratory activity of U87 but not of LN229 or HCT116 tumor cells. Such an increase in cell motility following irradiation in situ could be the source of recurrence. In contrast, carbon ion treatment was associated with a dose-dependent decrease in migration with all cell lines and under all conditions investigated. The radiation-induced loss of cell motility was correlated, in most cases, with corresponding changes in β1 integrin expression. The photon-induced increase in cell migration was paralleled by an elevated phosphorylation status of the epidermal growth factor receptor and AKT-ERK1/2 pathway. Such a hyperphosphorylation did not occur during (12)C(+6) irradiation under all conditions registered. Comparing the gene toxicity of X-rays with that of particles using the γH2AX technique in organotypic cultures of the oral

  5. Differential Superiority of Heavy Charged-Particle Irradiation to X-Rays: Studies on Biological Effectiveness and Side Effect Mechanisms in Multicellular Tumor and Normal Tissue Models

    Science.gov (United States)

    Walenta, Stefan; Mueller-Klieser, Wolfgang

    2016-01-01

    This review is focused on the radiobiology of carbon ions compared to X-rays using multicellular models of tumors and normal mucosa. The first part summarizes basic radiobiological effects, as observed in cancer cells. The second, more clinically oriented part of the review, deals with radiation-induced cell migration and mucositis. Multicellular spheroids from V79 hamster cells were irradiated with X-rays or carbon ions under ambient or restricted oxygen supply conditions. Reliable oxygen enhancement ratios could be derived to be 2.9, 2.8, and 1.4 for irradiation with photons, 12C+6 in the plateau region, and 12C+6 in the Bragg peak, respectively. Similarly, a relative biological effectiveness of 4.3 and 2.1 for ambient pO2 and hypoxia was obtained, respectively. The high effectiveness of carbon ions was reflected by an enhanced accumulation of cells in G2/M and a dose-dependent massive induction of apoptosis. These data clearly show that heavy charged particles are more efficient in sterilizing tumor cells than conventional irradiation even under hypoxic conditions. Clinically relevant doses (3 Gy) of X-rays induced an increase in migratory activity of U87 but not of LN229 or HCT116 tumor cells. Such an increase in cell motility following irradiation in situ could be the source of recurrence. In contrast, carbon ion treatment was associated with a dose-dependent decrease in migration with all cell lines and under all conditions investigated. The radiation-induced loss of cell motility was correlated, in most cases, with corresponding changes in β1 integrin expression. The photon-induced increase in cell migration was paralleled by an elevated phosphorylation status of the epidermal growth factor receptor and AKT-ERK1/2 pathway. Such a hyperphosphorylation did not occur during 12C+6 irradiation under all conditions registered. Comparing the gene toxicity of X-rays with that of particles using the γH2AX technique in organotypic cultures of the oral mucosa, the

  6. Response of radiochromic dye films to low energy heavy charged particles

    CERN Document Server

    Buenfil, A E; Gamboa-Debuen, I; Aviles, P; Avila, O; Olvera, C; Robledo, R; Rodriguez-Ponce, M; Mercado-Uribe, H; Rodriguez-Villafuerte, M; Brandan, M E

    2002-01-01

    We have studied the possible use of radiochromic dye films (RCF) as heavy charged particle dosemeters. We present the results of irradiating two commercial RCF (GafChromic HD-810 and MD-55-1) with 1.5, 2.9 and 4.4 MeV protons, 1.4, 2.8, 4.7, 5.9, 6.8 MeV sup 4 He ions and 8.5 and 12.4 MeV sup 1 sup 2 C ions, at proton doses from about 1 Gy up to 3 kGy, helium ions doses from 3 Gy to 5 kGy and carbon ion doses from 30 Gy to 20 kGy. The films were scanned and digitized using commercial equipment. For a given particle, the response per unit dose at different energies indicates an energy dependence of the sensitivity, which is discussed. Comparison was made for the use of a standard spectrophotometer to obtain optical density readings versus a white light scanner.

  7. Heavy-metal-induced reactive oxygen species: phytotoxicity and physicochemical changes in plants.

    Science.gov (United States)

    Shahid, Muhammad; Pourrut, Bertrand; Dumat, Camille; Nadeem, Muhammad; Aslam, Muhammad; Pinelli, Eric

    2014-01-01

    As a result of the industrial revolution, anthropogenic activities have enhanced there distribution of many toxic heavy metals from the earth's crust to different environmental compartments. Environmental pollution by toxic heavy metals is increasing worldwide, and poses a rising threat to both the environment and to human health.Plants are exposed to heavy metals from various sources: mining and refining of ores, fertilizer and pesticide applications, battery chemicals, disposal of solid wastes(including sewage sludge), irrigation with wastewater, vehicular exhaust emissions and adjacent industrial activity.Heavy metals induce various morphological, physiological, and biochemical dysfunctions in plants, either directly or indirectly, and cause various damaging effects. The most frequently documented and earliest consequence of heavy metal toxicity in plants cells is the overproduction of ROS. Unlike redox-active metals such as iron and copper, heavy metals (e.g, Pb, Cd, Ni, AI, Mn and Zn) cannot generate ROS directly by participating in biological redox reactions such as Haber Weiss/Fenton reactions. However, these metals induce ROS generation via different indirect mechanisms, such as stimulating the activity of NADPH oxidases, displacing essential cations from specific binding sites of enzymes and inhibiting enzymatic activities from their affinity for -SH groups on the enzyme.Under normal conditions, ROS play several essential roles in regulating the expression of different genes. Reactive oxygen species control numerous processes like the cell cycle, plant growth, abiotic stress responses, systemic signalling, programmed cell death, pathogen defence and development. Enhanced generation of these species from heavy metal toxicity deteriorates the intrinsic antioxidant defense system of cells, and causes oxidative stress. Cells with oxidative stress display various chemical,biological and physiological toxic symptoms as a result of the interaction between ROS and

  8. Alpha-particle energy spectra measured at forward angles in heavy-ion-induced reactions

    International Nuclear Information System (INIS)

    Borcea, C.; Cierlic, E.; Kalpakchieva, R.; Oganessian, Yu.Ts.; Penionzhkevich, Yu.E.

    1980-01-01

    Energy spectra have been measured for α-particles emitted in the bombardment of 159 Tb, 181 Ta, 197 Au, and 232 Th nuclei by 20 Ne, 22 Ne, and 40 Ar projectiles. The reaction products emitted in the angular range (0+-2)deg relative to the beam direction were analyzed using a magnetic spectrometer and detected by means of a semiconductor ΔE-E telescope. It was found that in all cases the experimentally measured maximum α-particle energy almost amounts to the maximum possible value calculated from the reaction energy balance for a two-body exit channel. A correlation was found between the measured absolute cross section in different target-projectile combinations and the α-particle binding energy in the target nuclei. On the basis of the obtained results a conclusion has been drawn that the α-particles are emitted in the early stage of the reaction

  9. Pre-equilibrium emission of nucleons from reactions induced by medium-energy heavy ions

    International Nuclear Information System (INIS)

    Korolija, M.; Holuh, E.; Cindro, N.; Hilscher, D.

    1984-01-01

    Recent data on fast-nucleon emission in heavy-ion-induced reactions are analysed successfully in terms of pre-equilibrium models; it is shown that the relevant parameters of those models preserve the physical meaning they have in light-ion-induced reactions. The initial exciton number obtained from a Griffin-plot analysis and the initial number of degrees of freedom, which is the relevant parameter of the modified HMB model, appear to be approximately equal for a given reaction at a given energy. It is inferred that, for heavy-ion reactions, the determination of such a parameter is substantially dominated by the centre-of-mass energy per nucleon above the Coulomb barrier, in contrast with the results of nucleon-induced reactions

  10. Molecular Mechanisms of Particle Ration Induced Apoptosis in Lymphocyte

    Science.gov (United States)

    Shi, Yufang

    Space radiation, composed of high-energy charged nuclei (HZE particles) and protons, has been previously shown to severely impact immune homeostasis in mice. To determine the molecular mechanisms that mediate acute lymphocyte depletion following exposure to HZE particle radiation mice were exposed to particle radiation beams at Brookhaven National Laboratory. We found that mice given whole body 5 6Fe particle irradiation (1GeV /n) had dose-dependent losses in total lymphocyte numbers in the spleen and thymus (using 200, 100 and 50 cGy), with thymocytes being more sensitive than splenocytes. All phenotypic subsets were reduced in number. In general, T cells and B cells were equally sensitive, while CD8+ T cells were more senstive than CD4+ T cells. In the thymus, immature CD4+CD8+ double-positive thymocytes were exquisitely sensitive to radiation-induced losses, single-positive CD4 or CD8 cells were less sensitive, and the least mature double negative cells were resistant. Irradiation of mice deficient in genes encoding essential apoptosis-inducing proteins revealed that the mechanism of lymphocyte depletion is independent of Fas ligand and TRAIL (TNF-ralated apoptosis-inducing ligand), in contrast to γ-radiation-induced lymphocyte losses which require the Fas-FasL pathway. Using inhibitors in vitro, lymphocyte apoptosis induced by HZE particle radiation was found to be caspase dependent, and not involve nitric oxide or oxygen free radicals.

  11. The semiclassical approximation for L- and M-shell coulomb ionization by heavy charged particles

    International Nuclear Information System (INIS)

    Kocbach, L.

    1975-08-01

    The semiclassical approximation with straight line trajectories is applied to the Coulomb ionization of K-, L- and M-shells by heavy charged particles. The calculational aspects are discussed in detail. Scaling relations for the experimentally relevant quantities are derived. The theoretical predictions are compared with experimental data. The relation of the present work to earlier SCA results and the PWBA results is discussed in detail. (auth)

  12. Search in leptonic channels for heavy resonances decaying to long-lived neutral particles

    Energy Technology Data Exchange (ETDEWEB)

    Chatrchyan, S.; Khachatryan, V.; Sirunyan, A. M.; Tumasyan, A.; Adam, W.; Aguilo, E.; Bergauer, T.; Dragicevic, M.; Erö, J.; Fabjan, C.; Friedl, M.; Frühwirth, R.; Ghete, V. M.; Hörmann, N.; Hrubec, J.; Jeitler, M.; Kiesenhofer, W.; Knünz, V.; Krammer, M.; Krätschmer, I.; Liko, D.; Mikulec, I.; Pernicka, M.; Rabady, D.; Rahbaran, B.; Rohringer, C.; Rohringer, H.; Schöfbeck, R.; Strauss, J.; Taurok, A.; Waltenberger, W.; Wulz, C. -E.; Mossolov, V.; Shumeiko, N.; Suarez Gonzalez, J.; Alderweireldt, S.; Bansal, M.; Bansal, S.; Cornelis, T.; De Wolf, E. A.; Janssen, X.; Luyckx, S.; Mucibello, L.; Ochesanu, S.; Roland, B.; Rougny, R.; Selvaggi, M.; Van Haevermaet, H.; Van Mechelen, P.; Van Remortel, N.; Van Spilbeeck, A.; Blekman, F.; Blyweert, S.; D’Hondt, J.; Gonzalez Suarez, R.; Kalogeropoulos, A.; Maes, M.; Olbrechts, A.; Tavernier, S.; Van Doninck, W.; Van Mulders, P.; Van Onsem, G. P.; Villella, I.; Clerbaux, B.; De Lentdecker, G.; Dero, V.; Gay, A. P. R.; Hreus, T.; Léonard, A.; Marage, P. E.; Mohammadi, A.; Reis, T.; Thomas, L.; Vander Velde, C.; Vanlaer, P.; Wang, J.; Adler, V.; Beernaert, K.; Cimmino, A.; Costantini, S.; Garcia, G.; Grunewald, M.; Klein, B.; Lellouch, J.; Marinov, A.; Mccartin, J.; Ocampo Rios, A. A.; Ryckbosch, D.; Sigamani, M.; Strobbe, N.; Thyssen, F.; Tytgat, M.; Walsh, S.; Yazgan, E.; Zaganidis, N.; Basegmez, S.; Bruno, G.; Castello, R.; Ceard, L.; Delaere, C.; du Pree, T.; Favart, D.; Forthomme, L.; Giammanco, A.; Hollar, J.; Lemaitre, V.; Liao, J.; Militaru, O.; Nuttens, C.; Pagano, D.; Pin, A.; Piotrzkowski, K.; Vizan Garcia, J. M.; Beliy, N.; Caebergs, T.; Daubie, E.; Hammad, G. H.; Alves, G. A.; Correa Martins, M.; Martins, T.; Pol, M. E.; Souza, M. H. G.; Aldá, W. L.; Carvalho, W.; Custódio, A.; Da Costa, E. M.; De Jesus Damiao, D.; De Oliveira Martins, C.; Fonseca De Souza, S.; Malbouisson, H.; Malek, M.; Matos Figueiredo, D.; Mundim, L.; Nogima, H.; Prado Da Silva, W. 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A.; D’Enterria, D.; Dabrowski, A.; De Roeck, A.; Di Guida, S.; Dobson, M.; Dupont-Sagorin, N.; Elliott-Peisert, A.; Frisch, B.; Funk, W.; Georgiou, G.; Giffels, M.; Gigi, D.; Gill, K.; Giordano, D.; Girone, M.; Giunta, M.; Glege, F.; Gomez-Reino Garrido, R.; Govoni, P.; Gowdy, S.; Guida, R.; Hammer, J.; Hansen, M.; Harris, P.; Hartl, C.; Harvey, J.; Hegner, B.; Hinzmann, A.; Innocente, V.; Janot, P.; Kaadze, K.; Karavakis, E.; Kousouris, K.; Lecoq, P.; Lee, Y. -J.; Lenzi, P.; Lourenço, C.; Magini, N.; Mäki, T.; Malberti, M.; Malgeri, L.; Mannelli, M.; Masetti, L.; Meijers, F.; Mersi, S.; Meschi, E.; Moser, R.; Mulders, M.; Musella, P.; Nesvold, E.; Orsini, L.; Palencia Cortezon, E.; Perez, E.; Perrozzi, L.; Petrilli, A.; Pfeiffer, A.; Pierini, M.; Pimiä, M.; Piparo, D.; Polese, G.; Quertenmont, L.; Racz, A.; Reece, W.; Rodrigues Antunes, J.; Rolandi, G.; Rovelli, C.; Rovere, M.; Sakulin, H.; Santanastasio, F.; Schäfer, C.; Schwick, C.; Segoni, I.; Sekmen, S.; Sharma, A.; Siegrist, P.; Silva, P.; Simon, M.; Sphicas, P.; Spiga, D.; Tsirou, A.; Veres, G. I.; Vlimant, J. R.; Wöhri, H. K.; Worm, S. D.; Zeuner, W. D.; Bertl, W.; Deiters, K.; Erdmann, W.; Gabathuler, K.; Horisberger, R.; Ingram, Q.; Kaestli, H. C.; König, S.; Kotlinski, D.; Langenegger, U.; Meier, F.; Renker, D.; Rohe, T.; Bachmair, F.; Bäni, L.; Bortignon, P.; Buchmann, M. A.; Casal, B.; Chanon, N.; Deisher, A.; Dissertori, G.; Dittmar, M.; Donegà, M.; Dünser, M.; Eller, P.; Eugster, J.; Freudenreich, K.; Grab, C.; Hits, D.; Lecomte, P.; Lustermann, W.; Marini, A. C.; Martinez Ruiz del Arbol, P.; Mohr, N.; Moortgat, F.; Nägeli, C.; Nef, P.; Nessi-Tedaldi, F.; Pandolfi, F.; Pape, L.; Pauss, F.; Peruzzi, M.; Ronga, F. J.; Rossini, M.; Sala, L.; Sanchez, A. K.; Starodumov, A.; Stieger, B.; Takahashi, M.; Tauscher, L.; Thea, A.; Theofilatos, K.; Treille, D.; Urscheler, C.; Wallny, R.; Weber, H. A.; Wehrli, L.; Amsler, C.; Chiochia, V.; De Visscher, S.; Favaro, C.; Ivova Rikova, M.; Kilminster, B.; Millan Mejias, B.; Otiougova, P.; Robmann, P.; Snoek, H.; Tupputi, S.; Verzetti, M.; Chang, Y. H.; Chen, K. H.; Ferro, C.; Kuo, C. M.; Li, S. W.; Lin, W.; Lu, Y. J.; Singh, A. P.; Volpe, R.; Yu, S. S.; Bartalini, P.; Chang, P.; Chang, Y. H.; Chang, Y. W.; Chao, Y.; Chen, K. F.; Dietz, C.; Grundler, U.; Hou, W. -S.; Hsiung, Y.; Kao, K. Y.; Lei, Y. J.; Lu, R. -S.; Majumder, D.; Petrakou, E.; Shi, X.; Shiu, J. G.; Tzeng, Y. M.; Wan, X.; Wang, M.; Asavapibhop, B.; Simili, E.; Srimanobhas, N.; Suwonjandee, N.; Adiguzel, A.; Bakirci, M. N.; Cerci, S.; Dozen, C.; Dumanoglu, I.; Eskut, E.; Girgis, S.; Gokbulut, G.; Gurpinar, E.; Hos, I.; Kangal, E. E.; Karaman, T.; Karapinar, G.; Kayis Topaksu, A.; Onengut, G.; Ozdemir, K.; Ozturk, S.; Polatoz, A.; Sogut, K.; Sunar Cerci, D.; Tali, B.; Topakli, H.; Vergili, L. N.; Vergili, M.; Akin, I. V.; Aliev, T.; Bilin, B.; Bilmis, S.; Deniz, M.; Gamsizkan, H.; Guler, A. M.; Ocalan, K.; Ozpineci, A.; Serin, M.; Sever, R.; Surat, U. E.; Yalvac, M.; Yildirim, E.; Zeyrek, M.; Gülmez, E.; Isildak, B.; Kaya, M.; Kaya, O.; Ozkorucuklu, S.; Sonmez, N.; Bahtiyar, H.; Barlas, E.; Cankocak, K.; Günaydin, Y. O.; Vardarlí, F. I.; Yücel, M.; Levchuk, L.; Brooke, J. J.; Clement, E.; Cussans, D.; Flacher, H.; Frazier, R.; Goldstein, J.; Grimes, M.; Heath, G. P.; Heath, H. F.; Kreczko, L.; Metson, S.; Newbold, D. M.; Nirunpong, K.; Poll, A.; Senkin, S.; Smith, V. J.; Williams, T.; Basso, L.; Bell, K. W.; Belyaev, A.; Brew, C.; Brown, R. M.; Cockerill, D. J. A.; Coughlan, J. A.; Harder, K.; Harper, S.; Jackson, J.; Kennedy, B. W.; Olaiya, E.; Petyt, D.; Radburn-Smith, B. C.; Shepherd-Themistocleous, C. H.; Tomalin, I. R.; Womersley, W. J.; Bainbridge, R.; Ball, G.; Beuselinck, R.; Buchmuller, O.; Colling, D.; Cripps, N.; Cutajar, M.; Dauncey, P.; Davies, G.; Della Negra, M.; Ferguson, W.; Fulcher, J.; Futyan, D.; Gilbert, A.; Guneratne Bryer, A.; Hall, G.; Hatherell, Z.; Hays, J.; Iles, G.; Jarvis, M.; Karapostoli, G.; Kenzie, M.; Lyons, L.; Magnan, A. -M.; Marrouche, J.; Mathias, B.; Nandi, R.; Nash, J.; Nikitenko, A.; Pela, J.; Pesaresi, M.; Petridis, K.; Pioppi, M.; Raymond, D. M.; Rogerson, S.; Rose, A.; Seez, C.; Sharp, P.; Sparrow, A.; Stoye, M.; Tapper, A.; Vazquez Acosta, M.; Virdee, T.; Wakefield, S.; Wardle, N.; Whyntie, T.; Chadwick, M.; Cole, J. E.; Hobson, P. R.; Khan, A.; Kyberd, P.; Leggat, D.; Leslie, D.; Martin, W.; Reid, I. D.; Symonds, P.; Teodorescu, L.; Turner, M.; Hatakeyama, K.; Liu, H.; Scarborough, T.; Charaf, O.; Cooper, S. I.; Henderson, C.; Rumerio, P.; Avetisyan, A.; Bose, T.; Fantasia, C.; Heister, A.; St. John, J.; Lawson, P.; Lazic, D.; Rohlf, J.; Sperka, D.; Sulak, L.; Alimena, J.; Bhattacharya, S.; Christopher, G.; Cutts, D.; Demiragli, Z.; Ferapontov, A.; Garabedian, A.; Heintz, U.; Jabeen, S.; Kukartsev, G.; Laird, E.; Landsberg, G.; Luk, M.; Narain, M.; Segala, M.; Sinthuprasith, T.; Speer, T.; Breedon, R.; Breto, G.; Calderon De La Barca Sanchez, M.; Chauhan, S.; Chertok, M.; Conway, J.; Conway, R.; Cox, P. T.; Dolen, J.; Erbacher, R.; Gardner, M.; Houtz, R.; Ko, W.; Kopecky, A.; Lander, R.; Mall, O.; Miceli, T.; Nelson, R.; Pellett, D.; Ricci-Tam, F.; Rutherford, B.; Searle, M.; Smith, J.; Squires, M.; Tripathi, M.; Vasquez Sierra, R.; Yohay, R.; Andreev, V.; Cline, D.; Cousins, R.; Duris, J.; Erhan, S.; Everaerts, P.; Farrell, C.; Hauser, J.; Ignatenko, M.; Jarvis, C.; Rakness, G.; Schlein, P.; Traczyk, P.; Valuev, V.; Weber, M.; Babb, J.; Clare, R.; Dinardo, M. E.; Ellison, J.; Gary, J. W.; Giordano, F.; Hanson, G.; Liu, H.; Long, O. R.; Luthra, A.; Nguyen, H.; Paramesvaran, S.; Sturdy, J.; Sumowidagdo, S.; Wilken, R.; Wimpenny, S.; Andrews, W.; Branson, J. G.; Cerati, G. B.; Cittolin, S.; Evans, D.; Holzner, A.; Kelley, R.; Lebourgeois, M.; Letts, J.; Macneill, I.; Mangano, B.; Padhi, S.; Palmer, C.; Petrucciani, G.; Pieri, M.; Sani, M.; Sharma, V.; Simon, S.; Sudano, E.; Tadel, M.; Tu, Y.; Vartak, A.; Wasserbaech, S.; Würthwein, F.; Yagil, A.; Yoo, J.; Barge, D.; Bellan, R.; Campagnari, C.; D’Alfonso, M.; Danielson, T.; Flowers, K.; Geffert, P.; George, C.; Golf, F.; Incandela, J.; Justus, C.; Kalavase, P.; Kovalskyi, D.; Krutelyov, V.; Lowette, S.; Magaña Villalba, R.; Mccoll, N.; Pavlunin, V.; Ribnik, J.; Richman, J.; Rossin, R.; Stuart, D.; To, W.; West, C.; Apresyan, A.; Bornheim, A.; Chen, Y.; Di Marco, E.; Duarte, J.; Gataullin, M.; Ma, Y.; Mott, A.; Newman, H. B.; Rogan, C.; Spiropulu, M.; Timciuc, V.; Veverka, J.; Wilkinson, R.; Xie, S.; Yang, Y.; Zhu, R. Y.; Azzolini, V.; Calamba, A.; Carroll, R.; Ferguson, T.; Iiyama, Y.; Jang, D. W.; Liu, Y. F.; Paulini, M.; Vogel, H.; Vorobiev, I.; Cumalat, J. P.; Drell, B. R.; Ford, W. T.; Gaz, A.; Luiggi Lopez, E.; Smith, J. G.; Stenson, K.; Ulmer, K. A.; Wagner, S. R.; Alexander, J.; Chatterjee, A.; Eggert, N.; Gibbons, L. K.; Heltsley, B.; Hopkins, W.; Khukhunaishvili, A.; Kreis, B.; Mirman, N.; Nicolas Kaufman, G.; Patterson, J. R.; Ryd, A.; Salvati, E.; Sun, W.; Teo, W. D.; Thom, J.; Thompson, J.; Tucker, J.; Vaughan, J.; Weng, Y.; Winstrom, L.; Wittich, P.; Winn, D.; Abdullin, S.; Albrow, M.; Anderson, J.; Bauerdick, L. A. T.; Beretvas, A.; Berryhill, J.; Bhat, P. C.; Burkett, K.; Butler, J. N.; Chetluru, V.; Cheung, H. W. K.; Chlebana, F.; Elvira, V. D.; Fisk, I.; Freeman, J.; Gao, Y.; Green, D.; Gutsche, O.; Hanlon, J.; Harris, R. M.; Hirschauer, J.; Hooberman, B.; Jindariani, S.; Johnson, M.; Joshi, U.; Klima, B.; Kunori, S.; Kwan, S.; Leonidopoulos, C.; Linacre, J.; Lincoln, D.; Lipton, R.; Lykken, J.; Maeshima, K.; Marraffino, J. M.; Martinez Outschoorn, V. I.; Maruyama, S.; Mason, D.; McBride, P.; Mishra, K.; Mrenna, S.; Musienko, Y.; Newman-Holmes, C.; O’Dell, V.; Prokofyev, O.; Sexton-Kennedy, E.; Sharma, S.; Spalding, W. J.; Spiegel, L.; Taylor, L.; Tkaczyk, S.; Tran, N. V.; Uplegger, L.; Vaandering, E. W.; Vidal, R.; Whitmore, J.; Wu, W.; Yang, F.; Yun, J. C.; Acosta, D.; Avery, P.; Bourilkov, D.; Chen, M.; Cheng, T.; Das, S.; De Gruttola, M.; Di Giovanni, G. P.; Dobur, D.; Drozdetskiy, A.; Field, R. D.; Fisher, M.; Fu, Y.; Furic, I. K.; Gartner, J.; Hugon, J.; Kim, B.; Konigsberg, J.; Korytov, A.; Kropivnitskaya, A.; Kypreos, T.; Low, J. F.; Matchev, K.; Milenovic, P.; Mitselmakher, G.; Muniz, L.; Park, M.; Remington, R.; Rinkevicius, A.; Sellers, P.; Skhirtladze, N.; Snowball, M.; Yelton, J.; Zakaria, M.; Gaultney, V.; Hewamanage, S.; Lebolo, L. M.; Linn, S.; Markowitz, P.; Martinez, G.; Rodriguez, J. L.; Adams, T.; Askew, A.; Bochenek, J.; Chen, J.; Diamond, B.; Gleyzer, S. V.; Haas, J.; Hagopian, S.; Hagopian, V.; Jenkins, M.; Johnson, K. F.; Prosper, H.; Veeraraghavan, V.; Weinberg, M.; Baarmand, M. M.; Dorney, B.; Hohlmann, M.; Kalakhety, H.; Vodopiyanov, I.; Yumiceva, F.; Adams, M. R.; Apanasevich, L.; Bai, Y.; Bazterra, V. E.; Betts, R. R.; Bucinskaite, I.; Callner, J.; Cavanaugh, R.; Evdokimov, O.; Gauthier, L.; Gerber, C. E.; Hofman, D. J.; Khalatyan, S.; Lacroix, F.; O’Brien, C.; Silkworth, C.; Strom, D.; Turner, P.; Varelas, N.; Akgun, U.; Albayrak, E. A.; Bilki, B.; Clarida, W.; Duru, F.; Griffiths, S.; Merlo, J. -P.; Mermerkaya, H.; Mestvirishvili, A.; Moeller, A.; Nachtman, J.; Newsom, C. R.; Norbeck, E.; Onel, Y.; Ozok, F.; Sen, S.; Tan, P.; Tiras, E.; Wetzel, J.; Yetkin, T.; Yi, K.; Barnett, B. A.; Blumenfeld, B.; Bolognesi, S.; Fehling, D.; Giurgiu, G.; Gritsan, A. V.; Guo, Z. J.; Hu, G.; Maksimovic, P.; Swartz, M.; Whitbeck, A.; Baringer, P.; Bean, A.; Benelli, G.; Kenny, R. P.; Murray, M.; Noonan, D.; Sanders, S.; Stringer, R.; Tinti, G.; Wood, J. S.; Barfuss, A. F.; Bolton, T.; Chakaberia, I.; Ivanov, A.; Khalil, S.; Makouski, M.; Maravin, Y.; Shrestha, S.; Svintradze, I.; Gronberg, J.; Lange, D.; Rebassoo, F.; Wright, D.; Baden, A.; Calvert, B.; Eno, S. C.; Gomez, J. A.; Hadley, N. J.; Kellogg, R. G.; Kirn, M.; Kolberg, T.; Lu, Y.; Marionneau, M.; Mignerey, A. C.; Pedro, K.; Peterman, A.; Skuja, A.; Temple, J.; Tonjes, M. B.; Tonwar, S. C.; Apyan, A.; Bauer, G.; Bendavid, J.; Busza, W.; Butz, E.; Cali, I. A.; Chan, M.; Dutta, V.; Gomez Ceballos, G.; Goncharov, M.; Kim, Y.; Klute, M.; Krajczar, K.; Levin, A.; Luckey, P. D.; Ma, T.; Nahn, S.; Paus, C.; Ralph, D.; Roland, C.; Roland, G.; Rudolph, M.; Stephans, G. S. F.; Stöckli, F.; Sumorok, K.; Sung, K.; Velicanu, D.; Wenger, E. A.; Wolf, R.; Wyslouch, B.; Yang, M.; Yilmaz, Y.; Yoon, A. S.; Zanetti, M.; Zhukova, V.; Dahmes, B.; De Benedetti, A.; Franzoni, G.; Gude, A.; Kao, S. C.; Klapoetke, K.; Kubota, Y.; Mans, J.; Pastika, N.; Rusack, R.; Sasseville, M.; Singovsky, A.; Tambe, N.; Turkewitz, J.; Cremaldi, L. M.; Kroeger, R.; Perera, L.; Rahmat, R.; Sanders, D. A.; Avdeeva, E.; Bloom, K.; Bose, S.; Claes, D. R.; Dominguez, A.; Eads, M.; Keller, J.; Kravchenko, I.; Lazo-Flores, J.; Malik, S.; Snow, G. R.; Godshalk, A.; Iashvili, I.; Jain, S.; Kharchilava, A.; Kumar, A.; Rappoccio, S.; Wan, Z.; Alverson, G.; Barberis, E.; Baumgartel, D.; Chasco, M.; Haley, J.; Nash, D.; Orimoto, T.; Trocino, D.; Wood, D.; Zhang, J.; Anastassov, A.; Hahn, K. A.; Kubik, A.; Lusito, L.; Mucia, N.; Odell, N.; Ofierzynski, R. A.; Pollack, B.; Pozdnyakov, A.; Schmitt, M.; Stoynev, S.; Velasco, M.; Won, S.; Berry, D.; Brinkerhoff, A.; Chan, K. M.; Hildreth, M.; Jessop, C.; Karmgard, D. J.; Kolb, J.; Lannon, K.; Luo, W.; Lynch, S.; Marinelli, N.; Morse, D. M.; Pearson, T.; Planer, M.; Ruchti, R.; Slaunwhite, J.; Valls, N.; Wayne, M.; Wolf, M.; Antonelli, L.; Bylsma, B.; Durkin, L. S.; Hill, C.; Hughes, R.; Kotov, K.; Ling, T. Y.; Puigh, D.; Rodenburg, M.; Vuosalo, C.; Williams, G.; Winer, B. L.; Berry, E.; Elmer, P.; Halyo, V.; Hebda, P.; Hegeman, J.; Hunt, A.; Jindal, P.; Koay, S. A.; Lopes Pegna, D.; Lujan, P.; Marlow, D.; Medvedeva, T.; Mooney, M.; Olsen, J.; Piroué, P.; Quan, X.; Raval, A.; Saka, H.; Stickland, D.; Tully, C.; Werner, J. S.; Zenz, S. C.; Zuranski, A.; Brownson, E.; Lopez, A.; Mendez, H.; Ramirez Vargas, J. E.; Alagoz, E.; Barnes, V. E.; Benedetti, D.; Bolla, G.; Bortoletto, D.; De Mattia, M.; Everett, A.; Hu, Z.; Jones, M.; Koybasi, O.; Kress, M.; Laasanen, A. T.; Leonardo, N.; Maroussov, V.; Merkel, P.; Miller, D. H.; Neumeister, N.; Shipsey, I.; Silvers, D.; Svyatkovskiy, A.; Vidal Marono, M.; Yoo, H. D.; Zablocki, J.; Zheng, Y.; Guragain, S.; Parashar, N.; Adair, A.; Akgun, B.; Boulahouache, C.; Ecklund, K. M.; Geurts, F. J. M.; Li, W.; Padley, B. P.; Redjimi, R.; Roberts, J.; Zabel, J.; Betchart, B.; Bodek, A.; Chung, Y. S.; Covarelli, R.; de Barbaro, P.; Demina, R.; Eshaq, Y.; Ferbel, T.; Garcia-Bellido, A.; Goldenzweig, P.; Han, J.; Harel, A.; Miner, D. C.; Vishnevskiy, D.; Zielinski, M.; Bhatti, A.; Ciesielski, R.; Demortier, L.; Goulianos, K.; Lungu, G.; Malik, S.; Mesropian, C.; Arora, S.; Barker, A.; Chou, J. P.; Contreras-Campana, C.; Contreras-Campana, E.; Duggan, D.; Ferencek, D.; Gershtein, Y.; Gray, R.; Halkiadakis, E.; Hidas, D.; Lath, A.; Panwalkar, S.; Park, M.; Patel, R.; Rekovic, V.; Robles, J.; Rose, K.; Salur, S.; Schnetzer, S.; Seitz, C.; Somalwar, S.; Stone, R.; Thomas, S.; Walker, M.; Cerizza, G.; Hollingsworth, M.; Spanier, S.; Yang, Z. C.; York, A.; Eusebi, R.; Flanagan, W.; Gilmore, J.; Kamon, T.; Khotilovich, V.; Montalvo, R.; Osipenkov, I.; Pakhotin, Y.; Perloff, A.; Roe, J.; Safonov, A.; Sakuma, T.; Sengupta, S.; Suarez, I.; Tatarinov, A.; Toback, D.; Akchurin, N.; Damgov, J.; Dragoiu, C.; Dudero, P. R.; Jeong, C.; Kovitanggoon, K.; Lee, S. W.; Libeiro, T.; Volobouev, I.; Appelt, E.; Delannoy, A. G.; Florez, C.; Greene, S.; Gurrola, A.; Johns, W.; Kurt, P.; Maguire, C.; Melo, A.; Sharma, M.; Sheldon, P.; Snook, B.; Tuo, S.; Velkovska, J.; Arenton, M. W.; Balazs, M.; Boutle, S.; Cox, B.; Francis, B.; Goodell, J.; Hirosky, R.; Ledovskoy, A.; Lin, C.; Neu, C.; Wood, J.; Gollapinni, S.; Harr, R.; Karchin, P. E.; Kottachchi Kankanamge Don, C.; Lamichhane, P.; Sakharov, A.; Anderson, M.; Belknap, Donald A.; Borrello, L.; Carlsmith, D.; Cepeda, M.; Dasu, S.; Friis, E.; Gray, L.; Grogg, K. S.; Grothe, M.; Hall-Wilton, R.; Herndon, M.; Hervé, A.; Klabbers, P.; Klukas, J.; Lanaro, A.; Lazaridis, C.; Loveless, R.; Mohapatra, A.; Mozer, M. U.; Ojalvo, I.; Palmonari, F.; Pierro, G. A.; Ross, I.; Savin, A.; Smith, W. H.; Swanson, J.

    2013-02-01

    A search is performed for heavy resonances decaying to two long-lived massive neutral particles, each decaying to leptons. The experimental signature is a distinctive topology consisting of a pair of oppositely charged leptons originating at a separated secondary vertex. Events were collected by the CMS detector at the LHC during pp collisions at TeV, and selected from data samples corresponding to 4.1 (5.1) fb-1 of integrated luminosity in the electron (muon) channel. No significant excess is observed above standard model expectations, and an upper limit is set with 95% confidence level on the production cross section times the branching fraction to leptons, as a function of the long-lived massive neutral particle lifetime.

  13. Nitric oxide-mediated bystander signal transduction induced by heavy-ion microbeam irradiation

    Science.gov (United States)

    Tomita, Masanori; Matsumoto, Hideki; Funayama, Tomoo; Yokota, Yuichiro; Otsuka, Kensuke; Maeda, Munetoshi; Kobayashi, Yasuhiko

    2015-07-01

    In general, a radiation-induced bystander response is known to be a cellular response induced in non-irradiated cells after receiving bystander signaling factors released from directly irradiated cells within a cell population. Bystander responses induced by high-linear energy transfer (LET) heavy ions at low fluence are an important health problem for astronauts in space. Bystander responses are mediated via physical cell-cell contact, such as gap-junction intercellular communication (GJIC) and/or diffusive factors released into the medium in cell culture conditions. Nitric oxide (NO) is a well-known major initiator/mediator of intercellular signaling within culture medium during bystander responses. In this study, we investigated the NO-mediated bystander signal transduction induced by high-LET argon (Ar)-ion microbeam irradiation of normal human fibroblasts. Foci formation by DNA double-strand break repair proteins was induced in non-irradiated cells, which were co-cultured with those irradiated by high-LET Ar-ion microbeams in the same culture plate. Foci formation was suppressed significantly by pretreatment with an NO scavenger. Furthermore, NO-mediated reproductive cell death was also induced in bystander cells. Phosphorylation of NF-κB and Akt were induced during NO-mediated bystander signaling in the irradiated and bystander cells. However, the activation of these proteins depended on the incubation time after irradiation. The accumulation of cyclooxygenase-2 (COX-2), a downstream target of NO and NF-κB, was observed in the bystander cells 6 h after irradiation but not in the directly irradiated cells. Our findings suggest that Akt- and NF-κB-dependent signaling pathways involving COX-2 play important roles in NO-mediated high-LET heavy-ion-induced bystander responses. In addition, COX-2 may be used as a molecular marker of high-LET heavy-ion-induced bystander cells to distinguish them from directly irradiated cells, although this may depend on the time

  14. Inner shell coulomb ionization by heavy charged particles studied by the SCA model

    International Nuclear Information System (INIS)

    Hansteen, J.M.

    1976-06-01

    An outline is given of the development of and some achievements hitherto gained from the semi-classical approximation (SCA) model of atomic Coulomb excitation by heavy charged particles. A few very recent results (1975-1976) are incorporated in the discussion. The SCA model has by now reached a mature state. Hence it seems reasonable to regard the atomic Coulomb excitation phenomenon as part of the extremely complicated excitation mechanism operative in the general ion-atom collision. A clear understanding of the complicated X-ray producing mechanisms in heavy-ion-atom collisions is lacking at present. Despite these facts, the conceptually simple SCA model has furthered our understanding far beyond initial expectations. Moreover, this model has at the same time provided a well-founded starting point for continued researches in this rapidly expanding field of physics. (JIW)

  15. Stable Heavy Hadrons in ATLAS

    CERN Document Server

    Mackeprang, Rasmus

    2007-01-01

    Several extensions to the SM feature heavy long-lived particles with masses of O(10^2-10^3 GeV) and mean lifetimes fulfilling $CT \\geq 10m$. Among such theories are supersymmetric scenarios as well as extra-dimensional models in which the heavy new particles are seen as Kaluza-Klein excitations of the well-known SM particles. Such particles will, from the point of view of a collider experiment be seen as stable. This thesis is concerned with the case where the exotic heavy particles emph{can} be considered stable while traversing the detector. Specifically the case is considered where the particles in question carry the charge of the strong nuclear force, commonly referred to as emph{colour charge}. A simulation kit has been developed using GEANT4. This framework is the current standard in experimental particle physics for the simulation of interactions of particles with matter, and it is used extensively for detector simulation. The simulation describes the interactions of these particles with matter which i...

  16. Heavy-heavy and heavy-light quarks interactions generated by QCD vacuum

    Directory of Open Access Journals (Sweden)

    Musakhanov Mirzayusuf

    2017-01-01

    Full Text Available The QCD vacuum is populated by instantons that correspond to the tunneling processes in the vacuum. This mechanism creates the strong vacuum gluon fields. As result, the QCD vacuum instantons induce very strong interactions between light quarks, initially almost massless. Such a strong interactions bring a large dynamical mass M of the light quarks and bound them to produce almost massless pions in accordance with the spontaneous breaking of the chiral symmetry (SBCS. On the other hand, the QCD vacuum instantons also interact with heavy quarks and responsible for the generation of the heavy-heavy and heavy-light quarks interactions, with a traces of the SBCS. If we take the average instanton size ρ¯=0.33$\\bar \\rho = 0.33$ fm, and the average inter-instanton distance R¯=1$\\bar R = 1$ fm we obtain the dynamical light quark mass to be M = 365 MeV and the instanton media contribution to the heavy quark mass ΔM=70 MeV. These factors define the coupling between heavy-light and heavy-heavy quarks induced by the QCD vacuum instantons. We consider first the instanton effects on the heavy-heavy quarks potential, including its spin-dependent part. We also discuss those effects on the masses of the charmonia and their hyperfine mass splittings. At the second part we discuss the interaction between a heavy and light quarks generated by instantons and it’s effects.

  17. Theory of one-dimensional hopping motion of a heavy particle interacting with phonons by different couplings

    Science.gov (United States)

    Itai, K.

    1987-02-01

    Two models which describe one-dimensional hopping motion of a heavy particle interacting with phonons are discussed. Model A corresponds to hopping in 1D metals or to the polaron problem. In model B the momentum dependence of the particle-phonon coupling is proportional to k-1/2. The scaling equations show that only in model B does localization occur for a coupling larger than a critical value. In the localization region this model shows close analogy to the Caldeira-Leggett model for macroscopic quantum tunneling.

  18. The average angular distribution of emitted particles in multi-step compound processes

    International Nuclear Information System (INIS)

    Bonetti, R.; Carlson, B.V.; Hussein, M.S.; Toledo, A.S. de

    1983-05-01

    A simple model for the differential cross-section that describes the angular distribution of emitted particles in heavy-ion induced multi-step compound reactions, is constructed. It is suggested that through a careful analysis of the deviations of the experimental data from the pure Hauser-Feshbach behaviour may shed light on the physical nature of the pre-compound, heavy-ion configuration. (Author) [pt

  19. Particle induced x-ray emission studies of some Indian medicinal plants

    International Nuclear Information System (INIS)

    Nomita Devi, K.; Nandakumar Sarma, H.; Kumar, Sanjiv

    2007-01-01

    Medicinal herbs have been used from antiquity by humanity. This paper discusses the elemental composition and concentration of ten Indian medicinal plants investigated by particle induced X-ray emission (PIXE) technique. The accuracy and precision of the technique were assured by analyzing three Certified Standard Reference Materials -cabbage- (GBW 08504, China), wheat flour (NIST-8436) and bovine liver (NIST-1577b). The element K, Ca, Mn, Fe, Cu and Zn were found to be present in all the samples in varying concentrations. No toxic heavy metals such as As, Pb and Hg were detected in the studied plants. The range of the elemental concentrations in dry weight has been found to vary from 4.69x10 4 mg/kg to 1.81 mg/kg in the plants. The results also show that these plants contain elements of vital importance in man's metabolism and that are needed for growth and developments, prevention and heating of diseases. (author)

  20. Heavy Metal-Induced Oxidative DNA Damage in Earthworms: A Review

    Directory of Open Access Journals (Sweden)

    Takeshi Hirano

    2010-01-01

    Full Text Available Earthworms can be used as a bio-indicator of metal contamination in soil, Earlier reports claimed the bioaccumulation of heavy metals in earthworm tissues, while the metal-induced mutagenicity reared in contaminated soils for long duration. But we examined the metal-induced mutagenicity in earthworms reared in metal containing culture beddings. In this experiment we observed the generation of 8-oxoguanine (8-oxo-Gua in earthworms exposed to cadmium and nickel in soil. 8-oxo-Gua is a major premutagenic form of oxidative DNA damage that induces GC-to-TA point mutations, leading to carcinogenesis.

  1. The Current Status and Future Directions of Heavy Charged Particle Therapy in Medicine

    Science.gov (United States)

    Levy, Richard P.; Blakely, Eleanor A.; Chu, William T.; Coutrakon, George B.; Hug, Eugen B.; Kraft, Gerhard; Tsujii, Hirohiko

    2009-03-01

    As aggressive, 3D-conformal treatment has become the clearly accepted goal of radiation oncology, heavy charged-particle treatment with protons and heavier ions has concurrently and relentlessly ascended to the forefront. Protons and helium nuclei, with relatively low linear-energy-transfer (LET) properties, have consistently been demonstrated to be beneficial for aggressive (high-dose) local treatment of many types of tumors. Protons have been applied to the majority of solid tumors, and have reached a high degree of general acceptance in radiation oncology after three decades and 55,000 patients treated. However, some 15% to 20% of tumor types have proven resistant to even the most aggressive low-LET irradiation. For these radio-resistant tumors, treatment with heavier ions (e.g., carbon) offers great potential benefit. These high-LET particles have increased relative biological effectiveness (RBE) that reaches its maximum in the Bragg peak. Irradiation with these heavier ions offers the unique combination of excellent 3D-dose distribution and increased RBE. We are presently witnessing several, important parallel developments in particle therapy. Protons will likely continue their exponential growth phase, and more compact design systems will make protons available to a larger patient population—thus becoming the "heavy charged particle of choice" for Cancer Centers with limited financial resources. In parallel, major academic efforts will further advance the field of heavier ion therapy, exploring all opportunities for particle treatment and continuing the search for the ideal particle(s) for specific tumors. The future of ion therapy will be best realized by clinical trials that have ready access to top-quality delivery of both protons and heavier ions that can be accurately shaped for treatment of a specific pathology, and which will permit direct randomized-trial comparison of the effectiveness of the various ions for different diseases. Optimal results

  2. Differential effects of p53 on bystander phenotypes induced by gamma ray and high LET heavy ion radiation

    Science.gov (United States)

    He, Mingyuan; Dong, Chen; Konishi, Teruaki; Tu, Wenzhi; Liu, Weili; Shiomi, Naoko; Kobayashi, Alisa; Uchihori, Yukio; Furusawa, Yoshiya; Hei, Tom K.; Dang, Bingrong; Shao, Chunlin

    2014-04-01

    High LET particle irradiation has several potential advantages over γ-rays such as p53-independent response. The purpose of this work is to disclose the effect of p53 on the bystander effect induced by different LET irradiations and underlying mechanism. Lymphocyte cells of TK6 (wild type p53) and HMy2.CIR (mutated p53) were exposed to either low or high LET irradiation, then their mitochondrial dysfunction and ROS generation were detected. The micronuclei (MN) induction in HL-7702 hepatocytes co-cultured with irradiated lymphocytes was also measured. It was found that the mitochondrial dysfunction, p66Shc activation, and intracellular ROS were enhanced in TK6 but not in HMy2.CIR cells after γ-ray irradiation, but all of them were increased in both cell lines after carbon and iron irradiation. Consistently, the bystander effect of MN formation in HL-7702 cells was only triggered by γ-irradiated TK6 cells but not by γ-irradiated HMy2.CIR cells. But this bystander effect was induced by both lymphocyte cell lines after heavy ion irradiation. PFT-μ, an inhibitor of p53, only partly inhibited ROS generation and bystander effect induced by 30 keV/μm carbon-irradiated TK6 cells but failed to suppress the bystander effect induced by the TK6 cells irradiated with either 70 keV/μm carbon or 180 keV/μm iron. The mitochondrial inhibitors of rotenone and oligomycin eliminated heavy ion induced ROS generation in TK6 and HMy2.CIR cells and hence diminished the bystander effect on HL-7702 cells. These results clearly demonstrate that the bystander effect is p53-dependent for low LET irradiation, but it is p53-independent for high LET irradiation which may be because of p53-independent ROS generation due to mitochondrial dysfunction.

  3. Neutron-Induced Charged Particle Studies at LANSCE

    Science.gov (United States)

    Lee, Hye Young; Haight, Robert C.

    2014-09-01

    Direct measurements on neutron-induced charged particle reactions are of interest for nuclear astrophysics and applied nuclear energy. LANSCE (Los Alamos Neutron Science Center) produces neutrons in energy of thermal to several hundreds MeV. There has been an effort at LANSCE to upgrade neutron-induced charged particle detection technique, which follows on (n,z) measurements made previously here and will have improved capabilities including larger solid angles, higher efficiency, and better signal to background ratios. For studying cross sections of low-energy neutron induced alpha reactions, Frisch-gridded ionization chamber is designed with segmented anodes for improving signal-to-noise ratio near reaction thresholds. Since double-differential cross sections on (n,p) and (n,a) reactions up to tens of MeV provide important information on deducing nuclear level density, the ionization chamber will be coupled with silicon strip detectors (DSSD) in order to stop energetic charged particles. In this paper, we will present the status of this development including the progress on detector design, calibrations and Monte Carlo simulations. This work is funded by the US Department of Energy - Los Alamos National Security, LLC under Contract DE-AC52-06NA25396.

  4. Heavy Metals Induce Iron Deficiency Responses at Different Hierarchic and Regulatory Levels.

    Science.gov (United States)

    Lešková, Alexandra; Giehl, Ricardo F H; Hartmann, Anja; Fargašová, Agáta; von Wirén, Nicolaus

    2017-07-01

    In plants, the excess of several heavy metals mimics iron (Fe) deficiency-induced chlorosis, indicating a disturbance in Fe homeostasis. To examine the level at which heavy metals interfere with Fe deficiency responses, we carried out an in-depth characterization of Fe-related physiological, regulatory, and morphological responses in Arabidopsis ( Arabidopsis thaliana ) exposed to heavy metals. Enhanced zinc (Zn) uptake closely mimicked Fe deficiency by leading to low chlorophyll but high ferric-chelate reductase activity and coumarin release. These responses were not caused by Zn-inhibited Fe uptake via IRON-REGULATED TRANSPORTER (IRT1). Instead, Zn simulated the transcriptional response of typical Fe-regulated genes, indicating that Zn affects Fe homeostasis at the level of Fe sensing. Excess supplies of cobalt and nickel altered root traits in a different way from Fe deficiency, inducing only transient Fe deficiency responses, which were characterized by a lack of induction of the ethylene pathway. Cadmium showed a rather inconsistent influence on Fe deficiency responses at multiple levels. By contrast, manganese evoked weak Fe deficiency responses in wild-type plants but strongly exacerbated chlorosis in irt1 plants, indicating that manganese antagonized Fe mainly at the level of transport. These results show that the investigated heavy metals modulate Fe deficiency responses at different hierarchic and regulatory levels and that the interaction of metals with physiological and morphological Fe deficiency responses is uncoupled. Thus, this study not only emphasizes the importance of assessing heavy metal toxicities at multiple levels but also provides a new perspective on how Fe deficiency contributes to the toxic action of individual heavy metals. © 2017 American Society of Plant Biologists. All Rights Reserved.

  5. Medium-energy electrons and heavy ions in Jupiter's magnetosphere - Effects of lower hybrid wave-particle interactions

    Science.gov (United States)

    Barbosa, D. D.

    1986-01-01

    A theory of medium-energy (about keV) electrons and heavy ions in Jupiter's magnetosphere is presented. Lower hybrid waves are generated by the combined effects of a ring instability of neutral wind pickup ions and the modified two-stream instability associated with transport of cool Iogenic plasma. The quasi-linear energy diffusion coefficient for lower hybrid wave-particle interactions is evaluated, and several solutions to the diffusion equation are given. Calculations based on measured wave properties show that the noise substantially modifies the particle distribution functions. The effects are to accelerate superthermal ions and electrons to keV energies and to thermalize the pickup ions on time scales comparable to the particle residence time. The S(2+)/S(+) ratio at medium energies is a measure of the relative contribution from Iogenic thermal plasma and neutral wind ions, and this important quantity should be determined from future measurements. The theory also predicts a preferential acceleration of heavy ions with an accleration time that scales inversely with the root of the ion mass. Electrons accelerated by the process contribute to further reionization of the neutral wind by electron impact, thus providing a possible confirmation of Alfven's critical velocity effect in the Jovian magnetosphere.

  6. Elastic and radiative heavy quark interactions in ultra-relativistic heavy-ion collisions

    International Nuclear Information System (INIS)

    Uphoff, Jan; Fochler, Oliver; Xu, Zhe; Greiner, Carsten

    2015-01-01

    Elastic and radiative heavy quark interactions with light partons are studied with the partonic transport model named the Boltzmann approach to multiparton scatterings (BAMPSs). After calculating the cross section of radiative processes for finite masses in the improved Gunion–Bertsch approximation and verifying this calculation by comparing to the exact result, we study elastic and radiative heavy quark energy loss in a static medium of quarks and gluons. Furthermore, the full 3 + 1D space–time evolution of gluons, light quarks, and heavy quarks in ultra-relativistic heavy-ion collisions at the BNL Relativistic Heavy-Ion Collider (RHIC) and the CERN Large Hadron Collider (LHC) are calculated with BAMPS including elastic and radiative heavy flavor interactions. Treating light and heavy particles on the same footing in the same framework, we find that the experimentally measured nuclear modification factor of charged hadrons and D mesons at the LHC can be simultaneously described. In addition, we calculate the heavy flavor evolution with an improved screening procedure from hard-thermal-loop calculations and confront the results with experimental data of the nuclear modification factor and the elliptic flow of heavy flavor particles at the RHIC and the LHC. (paper)

  7. Composition of heavy ions in solar energetic particle events

    International Nuclear Information System (INIS)

    Fan, C.Y.; Gloeckler, G.

    1983-01-01

    Recent advances in determining the elemental, charge state, and isotopic composition of approximatelt 1 to 20 MeV per nucleon ions in solar energetic particle (SEP) events and outline our current understanding of the nature of solar and interplanetary processes which may explain the observations. Average values of relative abundances measured in a large number of SEP events were found to be roughly energy independent in the approx. 1 to approx. 20 MeV per nucleon range, and showed a systematic deviation from photospheric abundances which seems to be organized in terms of the first ionization potential of the ion. Direct measurements of the charge states of SEPs revealed the surprisingly common presence of energetic He(+) along with heavy ion with typically coronal ionization states. High resolution measurements of isotopic abundance ratios in a small number of SEP events showed these to be consistent with the universal composition except for the puzzling overabundance of the SEP(22)Ne/(20)Ne relative to this isotopes ratio in the solar wind. The broad spectrum of observed elemental abundance variations, which in their extreme result in composition anomalies characteristic of (3)He rich, heavy ion rich and carbon poor SEP events, along with direct measurements of the ionization states of SEPs provided essential information on the physical characteristics of, and conditions in the source regions, as well as important constraints to possible models for SEP production

  8. Effects of heavy particle irradiation on central nervous system

    International Nuclear Information System (INIS)

    Nojima, Kumie; Nakadai, Taeko; Khono, Yukio; Nagaoka, Shunji

    2004-01-01

    Effects of low dose heavy particle radiation to central nervous system were studied using mouse neonatal brain cells in culture exposed to heavy ions and X ray at fifth days of the culture. The subsequent biological effects were evaluated by an induction of apoptosis and the survivability of neurons focusing on the dependencies of the animal strains with different genetic types, and linear energy transfer (LET) of the different nucleons. Of the three mouse strains tested, SCID, B6, B6C3F1 and C3H, used for brain cell culture, SCID was the most sensitive. Radiation sensitivity of these cells ware SCID>B6>B6C3F1>C3H to both X-ray and carbon ion (290 MeV/n) when compared by 10% apoptotic induction. The LET dependency was compared with using SCID cells exposing to different ions, (X, C, Si, Ar, and Fe). Although no detectable LET dependency was observed at higher dose than 1 Gy, an enhancement was observed in the high LET region and at lower dose than 0.5 Gy. The survivability profiles of the neurons were different in the mouse strains and ions. Memory and learning function of adult mice were studied using water maze test after localized carbon- or iron-ion irradiation to hippocampus area. Memory function were rapidly decrease after irradiation both ions. C-ion group were recovered 20 weeks after irradiation, but Iron group were different. (author)

  9. Multiparticle production in heavy-ion reactions

    International Nuclear Information System (INIS)

    Pelte, D.

    1980-01-01

    This lecture is concerned with the question how many particles and what kind of them are produced in heavy-ion collisions at energies about 10 MeV/n. We tend to assume that heavy-ion reactions at this energy are binary reactions. The experimental set consisting of two large ionization chambers serving to detection, in coincidence, the reaction fragments is described. With this set-up a number of reactions induced on 27 Al, 28 Si and 40 Ca by the 32 S beam of 135 and 190 MeV energy has been studied. Two-fragments inclusive and exclusive reactions were investigated. The assumption of a sequential statistical decay gives the best agreement with the data for all analyzed cases. (H.M.)

  10. Test particle modeling of wave-induced energetic electron precipitation

    International Nuclear Information System (INIS)

    Chang, H.C.; Inan, U.S.

    1985-01-01

    A test particle computer model of the precipitation of radiation belt electrons is extended to compute the dynamic energy spectrum of transient electron fluxes induced by short-duration VLF wave packets traveling along the geomagnetic field lines. The model is adapted to estimate the count rate and associated spectrum of precipitated electrons that would be observed by satellite-based particle detectors with given geometric factor and orientation with respect to the magnetic field. A constant-frequency wave pulse and a lightning-induced whistler wave packet are used as examples of the stimulating wave signals. The effects of asymmetry of particle mirror heights in the two hemispheres and the atmospheric backscatter of loss cone particles on the computed precipitated fluxes are discussed

  11. Particle and jet production in heavy-ion collisions with the ATLAS detector at LHC

    CERN Document Server

    Debbe, R; The ATLAS collaboration

    2012-01-01

    Particles and jets produced in heavy ion collisions are used to understand the hot, dense matter created in these interactions. Because of its wide angular coverage, highly hermetic design, and high pT capabilities, the ATLAS detector at the LHC provides an ideal environment in which to study these collisions. ATLAS has measured a wide variety of observables characterizing the bulk medium properties as well as the response of the medium to high-pT probes. Measurements have been made of charged particle multiplicity, elliptic flow, and higher-order particle flow, which allow characterization of global properties of the system. For the first time at this energy, elliptic and higher order flow has been measured over 5 units of pseudorapidity, from -2.5 to 2.5, and over a broad range in transverse momentum, 0.5-20 GeV. The higher-order particle flow studies are providing new insight into the role of initial state geometric fluctuations in these observables, with results obtained for the first through the sixth Fo...

  12. Study of the interaction between heavy ions and integrated circuits using a pulsed laser beam

    International Nuclear Information System (INIS)

    Lewis, D.; Fouillat, P.; Pouget, V.; Lapuyade, H.

    2002-01-01

    A new pulsed laser beam equipment dedicated to the characterization of integrated circuit is presented. Using ultra-short laser pulses is a convenient way to simulate experimentally the spatial environment of integrated circuits when interactions with heavy ions occur. This experimental set-up can be considered as a complementary tool for particle accelerators to evaluate the hardness assurance of integrated circuits for space applications. These particles generate temporally electrical disturbance called Single Event Effect (SEE). The theoretical approach of an equivalence between heavy ions and a laser pulses is discussed. The experimental set-up and some relevant operational methodologies are presented. Experimental results demonstrate that the induced electrical responses due to an heavy ion or a laser pulse are quite similar. Some sensitivity mappings of integrated circuits provided by this test bench illustrate the capabilities and the limitations of this laser-based technique. Contrary to the particle accelerators, it provides useful information concerning the spatial and temporal dependences of SEE mechanisms. (authors)

  13. Defects induced by swift heavy ions in the 18R martensite of Cu-Zn-Al alloy

    International Nuclear Information System (INIS)

    Zelaya, Eugenia; Tolley, Alfredo; Condo, Adriana; Lovey, Francisco; Schumacher, G

    2003-01-01

    The swift heavy ion incidence over the surface of a given material produces a strong energy deposition in a nanometric scale.Swift heavy ions, of the order of one thousand of MeV, deposit their energy as electronic excitations.This highly localized deposition can induce metastable transformations within the material. For example, in martensitic NiTi alloys irradiated with swift heavy ions, it has been observed changes on the martensitic transformation temperature and amorphous areas induced by the irradiation.In this work, the effects produced by swift heavy ions on the martensitic 18R structure of Cu-Zn-Al alloy (Cu - 12.17 Zn - 17.92 Al, in %at) were analyzed.Crystalline samples were irradiated in a direction close to the [2 1 0] of 18R with Xe + 230 MeV, Au + of 350 MeV and Kr + of 200 MeV ion beams.Defects of the order of nanometers induced by the irradiation were observed by transmission electron microscopy (TEM) and high resolution electron microscopy (HREM).It was also observed, that the average size of the irradiation defects induced by Au + ion is larger than those induced by Xe + and Kr + ions.In this case, no relationship between the observed defects and the energy deposition was found in the 23 keV/nn to 48 keV/nn range

  14. Trace determination of heavy metal concentrations in fauna, flora and salt samples from Black Sea waters by charged particles - induced X-rays

    International Nuclear Information System (INIS)

    Badica, T.; Ciortea, C.; Dima, S.; Petrovici, A.; Popescu, I.; Serbanescu, O.

    1977-01-01

    Studies were performed on Black Sea pollution by charged particles induced X-rays spectra analysis, using alpha and 16 O beams. Fauna, flora and salt samples were analysed. We found some of the concentrations of pollutant elements to be below the accepted levels. (author)

  15. Multiple Coulomb scattering of high-energy heavy charged particle beams used in biology and medicine

    International Nuclear Information System (INIS)

    Wong, M.; Schimmerling, W.; Ludewigt, B.; Phillips, M.; Curtis, S.; Tobias, C.A.

    1987-01-01

    The authors measured lateral displacement and angular distributions of high-energy heavy charged particles emerging from a target at the Lawrence Berkeley Laboratory BEVALAC with beams used in radiobiology experiments. Multiple Coulomb scattering occurring in the target material generally spreads the beam laterally and increases its divergence. The apparatus consists of four sets of position-sensitive semiconductor detectors located along the beam line. Each providing two position signals and one energy signal. The difference between the two position signals is used to determine the particle position in one dimension. The two position signals are constrained to add up to the energy deposition signal in order to reject multiple-particle traversals. The vector directions for the incident and emerging particles are reconstructed in three dimensions from their measured coordinated positions. Lateral and angular distributions are reported for beams of high-energy neon, iron and uranium ions incident on targets of aluminum, cooper, lead and water

  16. Mathematic Model of Technical Process of Heavy Mixtures Classifying on the Basis of Dispersion of Particles Flight Path

    OpenAIRE

    Normahmad Ravshanov; Bozorboy Palvanov; Gulnora Shermatova

    2014-01-01

    The article presents mathematic model and results of computer calculations of heavy mixtures classifying and farm crops full seeds selection. They enable to determine major process parameters and variation range, providing maximum dispersion of particles flight path, depending on feedstock modules.

  17. Inducing Lift on Spherical Particles by Traveling Magnetic Fields

    Science.gov (United States)

    Mazuruk, Konstantin; Grugel, Richard N.; Rose, M. Franklin (Technical Monitor)

    2001-01-01

    Gravity induced sedimentation of suspensions is a serious drawback to many materials and biotechnology processes, a factor that can, in principle, be overcome by utilizing an opposing Lorentz body force. In this work we demonstrate the utility of employing a traveling magnetic field (TMF) to induce a lifting force on particles dispersed in the fluid. Theoretically, a model has been developed to ascertain the net force, induced by TMF, acting on a spherical body as a function of the fluid medium's electrical conductivity and other parameters. Experimentally, the model is compared to optical observations of particle motion in the presence of TMF.

  18. DNA damage and chromosome aberration induced by heavy-ion beams

    International Nuclear Information System (INIS)

    Takakura, Kahoru; Funada, Aya; Aoki, Mizuho; Furusawa, Yoshiya

    2003-01-01

    The aim of this study is to clarify the relation between cell death and chromosomal aberration in cultured human cells (human salivary gland (HSG) tumor cells and GM05389 human normal fibroblasts) irradiated with heavy ion beams on the basis of linear energy transfer (LET) values. The LET dependences of cell death were observed for the both cells by the method of colony assay. The LET dependences of the chromosomal aberrations, breaks and gaps, isochromatid breaks and exchanges were also observed for the both cells using the premature chromosome condensation (PCC) method. From these results it is suggested that exchange formation is essential for the cell death caused by heavy ion beam irradiation. It is suspected that the densely ionizing track structure of hight LET heavy ions inhibits the effective repair in the chromatid breaks and isochromatid breaks and finally induce much exchange in the cells, which should be essential cause of cell death. (author)

  19. Particle-induced pulmonary acute phase response may be the causal link between particle inhalation and cardiovascular disease

    DEFF Research Database (Denmark)

    Saber, Anne T.; Jacobsen, Nicklas R.; Jackson, Petra

    2014-01-01

    Inhalation of ambient and workplace particulate air pollution is associated with increased risk of cardiovascular disease. One proposed mechanism for this association is that pulmonary inflammation induces a hepatic acute phase response, which increases risk of cardiovascular disease. Induction...... epidemiological studies. In this review, we present and review emerging evidence that inhalation of particles (e.g., air diesel exhaust particles and nanoparticles) induces a pulmonary acute phase response, and propose that this induction constitutes the causal link between particle inhalation and risk...

  20. Cancellation of leading divergences in left-right electroweak model and heavy particles

    International Nuclear Information System (INIS)

    Andrianov, A.A.; Romanenko, N.V.

    1997-01-01

    The fine-tuning principles are analyzed in search for estimation of heavy-particle masses in the left-right symmetric model. The modification of Veltman condition based on the hypothesis of the compression between fermion and boson energies within the left-right model multiples is proposed. The hypothesis is supplied with the requirement of the stability under rescaling. With regard to these requirements the necessity of existence of right-handed Majorana neutrinos with masses of order of right-handed gauge bosons is shown and estimations on the top-quark which are in a good agreement with the experimental value are obtained

  1. Current signal of silicon detectors facing charged particles and heavy ions; Reponse en courant des detecteurs silicium aux particules chargees et aux ions lourds

    Energy Technology Data Exchange (ETDEWEB)

    Hamrita, H

    2005-07-01

    This work consisted in collecting and studying for the first time the shapes of current signals obtained from charged particles or heavy ions produced by silicon detectors. The document is divided into two main parts. The first consisted in reducing the experimental data obtained with charged particles as well as with heavy ions. These experiments were performed at the Orsay Tandem and at GANIL using LISE. These two experiments enabled us to create a data base formed of current signals with various shapes and various times of collection. The second part consisted in carrying out a simulation of the current signals obtained from the various ions. To obtain this simulation we propose a new model describing the formation of the signal. We used the data base of the signals obtained in experiments in order to constrain the three parameters of our model. In this model, the charge carriers created are regarded as dipoles and their density is related to the dielectric polarization in the silicon detector. This phenomenon induces an increase in permittivity throughout the range of the incident ion and consequently the electric field between the electrodes of the detector is decreased inside the trace. We coupled with this phenomenon a dissociation and extraction mode of the charge carriers so that they can be moved in the electric field. (author)

  2. DRIFT-INDUCED PERPENDICULAR TRANSPORT OF SOLAR ENERGETIC PARTICLES

    International Nuclear Information System (INIS)

    Marsh, M. S.; Dalla, S.; Kelly, J.; Laitinen, T.

    2013-01-01

    Drifts are known to play a role in galactic cosmic ray transport within the heliosphere and are a standard component of cosmic ray propagation models. However, the current paradigm of solar energetic particle (SEP) propagation holds the effects of drifts to be negligible, and they are not accounted for in most current SEP modeling efforts. We present full-orbit test particle simulations of SEP propagation in a Parker spiral interplanetary magnetic field (IMF), which demonstrate that high-energy particle drifts cause significant asymmetric propagation perpendicular to the IMF. Thus in many cases the assumption of field-aligned propagation of SEPs may not be valid. We show that SEP drifts have dependencies on energy, heliographic latitude, and charge-to-mass ratio that are capable of transporting energetic particles perpendicular to the field over significant distances within interplanetary space, e.g., protons of initial energy 100 MeV propagate distances across the field on the order of 1 AU, over timescales typical of a gradual SEP event. Our results demonstrate the need for current models of SEP events to include the effects of particle drift. We show that the drift is considerably stronger for heavy ion SEPs due to their larger mass-to-charge ratio. This paradigm shift has important consequences for the modeling of SEP events and is crucial to the understanding and interpretation of in situ observations

  3. Nuclear polarization potential due to particle transfer in heavy-ion collisions

    International Nuclear Information System (INIS)

    Landowne, S.; Dasso, C.H.; Winther, A.; Pollarolo, G.

    1986-01-01

    The effective interaction which determines the elastic scattering of heavy composite systems consists of a ''bare'' real potential V, noramally identified with the folding model, a renormalization term or ''polarization potential'' ΔV and an imaginary ''absorptive potential'' iW. The latter contributions originate from the couplings to intrinsic degrees of freedom. While iW is a conspicuous feature of all optical model analyses, the related term ΔV has received relatively little attention until recently. The microscopic structure of ΔV + iW is examined using second-order semi-classical perturbation theory. Focus is on the long-range part of ΔV which is governed by single-particle transfer reactions between the colliding systems

  4. Nuclear polarization potential due to particle transfer in heavy-ion collisions

    International Nuclear Information System (INIS)

    Landowne, S.; Dasso, C.H.; Winther, A.; Pollarolo, G.

    1986-01-01

    The effective interaction which determines the elastic scattering of heavy composite systems consists of a bare real potential V, normally identified with the folding model, a renormalization term or polarization potential ΔV and an imaginary absorptive potential iW. The latter contributions originate from the couplings to intrinsic degrees of freedom. While iW is a conspicuous feature of all optical model analyses, the related term ΔV has received relatively little attention until recently. Here the authors examine the microscopic structure of ΔV + IW using second-order semi-classical perturbation theory. In particular, they focus on the long-range part of ΔV which is governed by single-particle transfer reactions between the colliding systems

  5. 3D quantification of brain microvessels exposed to heavy particle radiation

    International Nuclear Information System (INIS)

    Hintermueller, C; Stampanoni, M; Coats, J S; Obenaus, A; Nelson, G; Krucker, T

    2009-01-01

    Space radiation with high energy particles and cosmic rays presents a significant hazard to spaceflight crews. Recent reviews of the health risk to astronauts from ionizing radiation concluded to establish a level of risk which may indicate the possible performance decrements and decreased latency of late dysfunction syndromes (LDS) of the brain. A hierarchical imaging approach developed at ETH Zuerich and PSI, which relies on synchrotron based X-ray Tomographic Microscopy (SRXTM), was used to visualize and analyze 3D vascular structures down to the capillary level in their precise anatomical context. Various morphological parameters, such as overall vessel volume, vessel thickness and spacing, are extracted to characterize the vascular structure within a region of interest. For a first quantification of the effect of high energy particles on the vasculature we scanned a set of 6 animals, all of same age. The animals were irradiated with 1 Gy, 2 Gy and 4 Gy of 600MeV 56 Fe heavy particles simulating the space radiation environment. We found that with increasing dose the diameter of vessels and the overall vessel volume are decreased whereas the vessel spacing is increased. As these parameters reflect blood flow in three-dimensional space they can be used as indicators for the degree of vascular efficiency which can have an impact on the function and development of lung tissue or tumors.

  6. Mutation induction by heavy ions

    Science.gov (United States)

    Kiefer, J.; Stoll, U.; Schneider, E.

    1994-10-01

    Mutation induction by heavy ions is compared in yeast and mammalian cells. Since mutants can only be recovered in survivors the influence of inactivation cross sections has to be taken into account. It is shown that both the size of the sensitive cellular site as well as track structure play an important role. Another parameter which influences the probability of mutation induction is repair: Contrary to naive assumptions primary radiation damage does not directly lead to mutations but requires modification to reconstitute the genetic machinery so that mutants can survive. The molecular structure of mutations was analyzed after exposure to deuterons by amplification with the aid of polymerase chain reaction. The results-although preliminary-demonstrate that even with densely ionizing particles a large fraction does not carry big deletions which suggests that point mutations may also be induced by heavy ions.

  7. Results of heavy ion radiotherapy

    International Nuclear Information System (INIS)

    Castro, J.R.

    1994-04-01

    The potential of heavy ion therapy for clinical use in cancer therapy stems from the biological parameters of heavy charged particles, and their precise dose localization. Biologically, carbon, neon and other heavy ion beams (up to about silicon) are clinically useful in overcoming the radioresistance of hypoxic tumors, thus increasing biological effectiveness relative to low-LET x-ray or electron beams. Cells irradiated by heavy ions show less variation in cell-cycle related radiosensitivity and decreased repair of radiation injury. The physical parameters of these heavy charged particles allow precise delivery of high radiation doses to tumors while minimizing irradiation of normal tissues. Clinical use requires close interaction between radiation oncologists, medical physicists, accelerator physicists, engineers, computer scientists and radiation biologists

  8. Polution of the environment by heavy metals

    International Nuclear Information System (INIS)

    Houtman, J.P.W.

    1980-01-01

    An overview is given of the problems caused by pollution of the environment by heavy metals and the important role played by nuclear examination methods such as activation analysis and particle induced X-ray emission. A number of examples taken from work initiated by the interuniversitair Reactor Instituut, demonstrate that this research should be continued and extended, particularly in relation to the expected increase in the use of coal for energy generation in electricity centres. (C.F.)

  9. Heavy-ion-induced sucrose radicals investigated using EPR and UV spectroscopy

    Science.gov (United States)

    Nakagawa, Kouichi; Karakirova, Yordanka; Yordanov, Nicola D.

    2015-01-01

    The potential use of a sucrose dosimeter for estimating both linear energy transfer (LET) and the absorbed dose of heavy ion and X-ray radiation was investigated. The stable free radicals were produced when sucrose was irradiated with heavy ions, such as helium, carbon, silicon and neon ions, and when the X-ray radiation was similar to the obtained electron paramagnetic resonance (EPR) spectra, which were ∼7 mT wide and composed of several hyperfine structures. In addition, the total spin concentration resulting from heavy-ion irradiation increased linearly as the absorbed dose increased, and decreased logarithmically as the LET increased. These empirical relations imply that the LET at a certain dose can be determined from the spin concentration. For sucrose and alanine, both cross-sections following C-ion irradiation with a 50 Gy dose were ∼1.3 × 10−12 [μm2], taking into account the molecular size of the samples. The values of these cross-sections imply that multiple ionizing particles were involved in the production of stable radicals. Furthermore, UV absorbance at 267 nm of an aqueous solution of irradiated sucrose was found to linearly increase with increasing absorbed dose. Therefore, the EPR and UV results suggest that sucrose can be a useful dosimeter for heavy-ion irradiation. PMID:25480828

  10. On the transport, segregation, and dispersion of heavy and light particles interacting with rising thermal plumes

    Science.gov (United States)

    Lappa, Marcello

    2018-03-01

    A systematic numerical analysis is carried out on the multiplicity of patterns produced by inertial particles dispersed in a fluid and localized gravitational convection developing in the form of a rising thermal plume. In particular, specific numerical examples are presented to provide inputs for an increased understanding of the underlying flow-particle interaction mechanisms and cause-and-effect relationships. A rich spectrum of convective dynamics is obtained at the relatively high value of the considered Rayleigh number (Ra = 108), which naturally allows the investigation of several intriguing effects (including, but not limited to, particle interaction with plume jet, associated vortices, shear instabilities, and symmetry breaking phenomena). An important degree of freedom is introduced in the problem by changing the particle viscous drag through proper tuning of the related Stokes number (St). Similarly, inertia and weight of solid matter are varied parametrically by performing numerical simulations for both light and heavy particles at different values of the Froude number. This framework lets us identify the average behavior of particles by revealing the mean evolution. We connect such statistics to the behavior of the temporally evolving thermal plume, giving deeper insights into the particle transport mechanisms and associated dissipative dynamics.

  11. Mathematic Model of Technical Process of Heavy Mixtures Classifying on the Basis of Dispersion of Particles Flight Path

    Directory of Open Access Journals (Sweden)

    Normahmad Ravshanov

    2014-05-01

    Full Text Available The article presents mathematic model and results of computer calculations of heavy mixtures classifying and farm crops full seeds selection. They enable to determine major process parameters and variation range, providing maximum dispersion of particles flight path, depending on feedstock modules.

  12. Heavy inertial particles in turbulent flows gain energy slowly but lose it rapidly

    Science.gov (United States)

    Bhatnagar, Akshay; Gupta, Anupam; Mitra, Dhrubaditya; Pandit, Rahul

    2018-03-01

    We present an extensive numerical study of the time irreversibility of the dynamics of heavy inertial particles in three-dimensional, statistically homogeneous, and isotropic turbulent flows. We show that the probability density function (PDF) of the increment, W (τ ) , of a particle's energy over a time scale τ is non-Gaussian, and skewed toward negative values. This implies that, on average, particles gain energy over a period of time that is longer than the duration over which they lose energy. We call this slow gain and fast loss. We find that the third moment of W (τ ) scales as τ3 for small values of τ . We show that the PDF of power-input p is negatively skewed too; we use this skewness Ir as a measure of the time irreversibility and we demonstrate that it increases sharply with the Stokes number St for small St; this increase slows down at St≃1 . Furthermore, we obtain the PDFs of t+ and t-, the times over which p has, respectively, positive or negative signs, i.e., the particle gains or loses energy. We obtain from these PDFs a direct and natural quantification of the slow gain and fast loss of the energy of the particles, because these PDFs possess exponential tails from which we infer the characteristic loss and gain times tloss and tgain, respectively, and we obtain tlossprobability in the strain-dominated region than in the vortical one; in contrast, the slow gain in the energy of the particles is equally likely in vortical or strain-dominated regions of the flow.

  13. Transverse energy and charged particle production in heavy-ion collisions: from RHIC to LHC

    International Nuclear Information System (INIS)

    Sahoo, Raghunath; Mishra, Aditya Nath

    2014-01-01

    We study the charged particle and transverse energy production mechanism from AGS, SPS, Relativistic Heavy-Ion Collider (RHIC) to Large Hadron Collider (LHC) energies in the framework of nucleon and quark participants. At RHIC and LHC energies, the number of nucleons-normalized charged particle and transverse energy density in pseudorapidity, which shows a monotonic rise with centrality, turns out to be an almost centrality independent scaling behavior when normalized to the number of participant quarks. A universal function which is a combination of logarithmic and power-law, describes well the charged particle and transverse energy production both at nucleon and quark participant level for the whole range of collision energies. Energy dependent production mechanisms are discussed both for nucleonic and partonic level. Predictions are made for the pseudorapidity densities of transverse energy, charged particle multiplicity and their ratio (the barometric observable, [dE T /dη]/[dN ch /dη] ≡ E T /N ch ) at mid-rapidity for Pb + Pb collisions at √s NN = 5.5 TeV. A comparison with models based on gluon saturation and statistical hadron gas is made for the energy dependence of E T /N ch . (author)

  14. Halogenated salicylaldehyde azines: The heavy atom effect on aggregation-induced emission enhancement properties

    International Nuclear Information System (INIS)

    Chen, Xiao-tong; Tong, Ai-jun

    2014-01-01

    This study investigates the heavy-atom effect (HAE) on aggregation-induced emission enhancement (AIEE) properties of salicylaldehyde azines. For this purpose, a series of halogenated salicylaldehyde azine derivatives, namely, chloro-salicylaldehyde azine (1), bromo-salicylaldehyde azine (2) and iodo-salicylaldehyde azine (3) are synthesized. 1 and 2 display typical AIEE characteristics of salicylaldehyde azine compounds; whereas for the iodo-substituent in 3, is found to be effective “external” heavy atom quenchers to salicylaldehyde azine fluorescence in aggregated state. Based on its weak fluorescence in aggregated state and relative strong fluorescence in dispersed state, 3 can also be applied as a turn-on fluorescence probe for egg albumin detection attributed to hydrophobic interaction. -- Highlights: • This study investigates the heavy-atom effect (HAE) on aggregation-induced emission enhancement (AIEE) properties of salicylaldehyde azines. • Chloro- and bromo-salicylaldehyde display typical AIEE properties of salicylaldehyde azine, whereas the iodo-substitute quenches AIEE in aggregated state. • Iodo-salicylaldehyde can be applied as a turn-on fluorescence probe for egg albumin detection attributed to hydrophobic interaction

  15. Investigation of structural materials of reactors using high-energy heavy-ion irradiations

    International Nuclear Information System (INIS)

    Wang Zhiguang

    2007-01-01

    Radiation damage in structural materials of fission/fusion reactors is mainly attributed to the evolution of intensive atom displacement damage induced by energetic particles (n, α and/or fission fragments) and high-rate helium doping by direct α particle bombardments and/or (n, α) reactions. It can cause severe degradation of reactor structural materials such as surface blistering, bulk void swelling, deformation, fatigue, embrittlement, stress erosion corrosion and so on that will significantly affect the operation safety of reactors. However, up to now, behavior of structural materials at the end of their service can hardly be fully tested in a real reactor. In the present work, damage process in reactor structural materials is briefly introduced, then the advantages of energetic ion implantation/irradiation especially high-energy heavy ion irradiation are discussed, and several typical examples on simulation of radiation effects in reactor candidate structural materials using high-energy heavy ion irradiations are pronounced. Experimental results and theoretical analysis suggested that irradiation with energetic particles especially high-energy heavy ions is very useful technique for simulating the evolution of microstructures and macro-properties of reactor structural materials. Furthermore, an on-going plan of material irradiation experiments using high energy H- and He-ions based on the Heavy Ion Research Facilities in Lanzhou (HIRFL) is also briefly interpreted. (authors)

  16. Search for metastable heavy charged particles with large ionisation energy loss in $pp$ collisions at $\\sqrt{s}$ = 8 TeV using the ATLAS experiment

    CERN Document Server

    Aad, Georges; Abdallah, Jalal; Abdinov, Ovsat; Aben, Rosemarie; Abolins, Maris; AbouZeid, Ossama; Abramowicz, Halina; Abreu, Henso; Abreu, Ricardo; Abulaiti, Yiming; Acharya, Bobby Samir; Adamczyk, Leszek; Adams, David; Adelman, Jahred; Adomeit, Stefanie; Adye, Tim; Affolder, Tony; Agatonovic-Jovin, Tatjana; Agricola, Johannes; Aguilar-Saavedra, Juan Antonio; Ahlen, Steven; Ahmadov, Faig; Aielli, Giulio; Akerstedt, Henrik; Åkesson, Torsten Paul Ake; Akimov, Andrei; Alberghi, Gian Luigi; Albert, Justin; Albrand, Solveig; Alconada Verzini, Maria Josefina; Aleksa, Martin; Aleksandrov, Igor; Alexa, Calin; Alexander, Gideon; Alexopoulos, Theodoros; Alhroob, Muhammad; Alimonti, Gianluca; Alio, Lion; Alison, John; Alkire, Steven Patrick; Allbrooke, Benedict; Allport, Phillip; Aloisio, Alberto; Alonso, Alejandro; Alonso, Francisco; Alpigiani, Cristiano; Altheimer, Andrew David; Alvarez Gonzalez, Barbara; Άlvarez Piqueras, Damián; Alviggi, Mariagrazia; Amadio, Brian Thomas; Amako, Katsuya; Amaral Coutinho, Yara; Amelung, Christoph; Amidei, Dante; Amor Dos Santos, Susana Patricia; Amorim, Antonio; Amoroso, Simone; Amram, Nir; Amundsen, Glenn; Anastopoulos, Christos; Ancu, Lucian Stefan; Andari, Nansi; Andeen, Timothy; Anders, Christoph Falk; Anders, Gabriel; Anders, John Kenneth; Anderson, Kelby; Andreazza, Attilio; Andrei, George Victor; Angelidakis, Stylianos; Angelozzi, Ivan; Anger, Philipp; Angerami, Aaron; Anghinolfi, Francis; Anisenkov, Alexey; Anjos, Nuno; Annovi, Alberto; Antonelli, Mario; Antonov, Alexey; Antos, Jaroslav; Anulli, Fabio; Aoki, Masato; Aperio Bella, Ludovica; Arabidze, Giorgi; Arai, Yasuo; Araque, Juan Pedro; Arce, Ayana; Arduh, Francisco Anuar; Arguin, Jean-Francois; Argyropoulos, Spyridon; Arik, Metin; Armbruster, Aaron James; Arnaez, Olivier; Arnal, Vanessa; Arnold, Hannah; Arratia, Miguel; Arslan, Ozan; Artamonov, Andrei; Artoni, Giacomo; Asai, Shoji; Asbah, Nedaa; Ashkenazi, Adi; Åsman, Barbro; Asquith, Lily; Assamagan, Ketevi; Astalos, Robert; Atkinson, Markus; Atlay, Naim Bora; Augsten, Kamil; Aurousseau, Mathieu; Avolio, Giuseppe; Axen, Bradley; Ayoub, Mohamad Kassem; Azuelos, Georges; Baak, Max; Baas, Alessandra; Baca, Matthew John; Bacci, Cesare; Bachacou, Henri; Bachas, Konstantinos; Backes, Moritz; Backhaus, Malte; Bagiacchi, Paolo; Bagnaia, Paolo; Bai, Yu; Bain, Travis; Baines, John; Baker, Oliver Keith; Baldin, Evgenii; Balek, Petr; Balestri, Thomas; Balli, Fabrice; Banas, Elzbieta; Banerjee, Swagato; Bannoura, Arwa A E; Bansil, Hardeep Singh; Barak, Liron; Barberio, Elisabetta Luigia; Barberis, Dario; Barbero, Marlon; Barillari, Teresa; Barisonzi, Marcello; Barklow, Timothy; Barlow, Nick; Barnes, Sarah Louise; Barnett, Bruce; Barnett, Michael; Barnovska, Zuzana; Baroncelli, Antonio; Barone, Gaetano; Barr, Alan; Barreiro, Fernando; Barreiro Guimarães da Costa, João; Bartoldus, Rainer; Barton, Adam Edward; Bartos, Pavol; Basalaev, Artem; Bassalat, Ahmed; Basye, Austin; Bates, Richard; Batista, Santiago Juan; Batley, Richard; Battaglia, Marco; Bauce, Matteo; Bauer, Florian; Bawa, Harinder Singh; Beacham, James Baker; Beattie, Michael David; Beau, Tristan; Beauchemin, Pierre-Hugues; Beccherle, Roberto; Bechtle, Philip; Beck, Hans Peter; Becker, Anne Kathrin; Becker, Maurice; Becker, Sebastian; Beckingham, Matthew; Becot, Cyril; Beddall, Andrew; Beddall, Ayda; Bednyakov, Vadim; Bee, Christopher; Beemster, Lars; Beermann, Thomas; Begel, Michael; Behr, Janna Katharina; Belanger-Champagne, Camille; Bell, William; Bella, Gideon; Bellagamba, Lorenzo; Bellerive, Alain; Bellomo, Massimiliano; Belotskiy, Konstantin; Beltramello, Olga; Benary, Odette; Benchekroun, Driss; Bender, Michael; Bendtz, Katarina; Benekos, Nektarios; Benhammou, Yan; Benhar Noccioli, Eleonora; Benitez Garcia, Jorge-Armando; Benjamin, Douglas; Bensinger, James; Bentvelsen, Stan; Beresford, Lydia; Beretta, Matteo; Berge, David; Bergeaas Kuutmann, Elin; Berger, Nicolas; Berghaus, Frank; Beringer, Jürg; Bernard, Clare; Bernard, Nathan Rogers; Bernius, Catrin; Bernlochner, Florian Urs; Berry, Tracey; Berta, Peter; Bertella, Claudia; Bertoli, Gabriele; Bertolucci, Federico; Bertsche, Carolyn; Bertsche, David; Besana, Maria Ilaria; Besjes, Geert-Jan; Bessidskaia Bylund, Olga; Bessner, Martin Florian; Besson, Nathalie; Betancourt, Christopher; Bethke, Siegfried; Bevan, Adrian John; Bhimji, Wahid; Bianchi, Riccardo-Maria; Bianchini, Louis; Bianco, Michele; Biebel, Otmar; Biedermann, Dustin; Bieniek, Stephen Paul; Biglietti, Michela; Bilbao De Mendizabal, Javier; Bilokon, Halina; Bindi, Marcello; Binet, Sebastien; Bingul, Ahmet; Bini, Cesare; Biondi, Silvia; Black, Curtis; Black, James; Black, Kevin; Blackburn, Daniel; Blair, Robert; Blanchard, Jean-Baptiste; Blanco, Jacobo Ezequiel; Blazek, Tomas; Bloch, Ingo; Blocker, Craig; Blum, Walter; Blumenschein, Ulrike; Bobbink, Gerjan; Bobrovnikov, Victor; Bocchetta, Simona Serena; Bocci, Andrea; Bock, Christopher; Boehler, Michael; Bogaerts, Joannes Andreas; Bogavac, Danijela; Bogdanchikov, Alexander; Bohm, Christian; Boisvert, Veronique; Bold, Tomasz; Boldea, Venera; Boldyrev, Alexey; Bomben, Marco; Bona, Marcella; Boonekamp, Maarten; Borisov, Anatoly; Borissov, Guennadi; Borroni, Sara; Bortfeldt, Jonathan; Bortolotto, Valerio; Bos, Kors; Boscherini, Davide; Bosman, Martine; Boudreau, Joseph; Bouffard, Julian; Bouhova-Thacker, Evelina Vassileva; Boumediene, Djamel Eddine; Bourdarios, Claire; Bousson, Nicolas; Boveia, Antonio; Boyd, James; Boyko, Igor; Bozic, Ivan; Bracinik, Juraj; Brandt, Andrew; Brandt, Gerhard; Brandt, Oleg; Bratzler, Uwe; Brau, Benjamin; Brau, James; Braun, Helmut; Brazzale, Simone Federico; Breaden Madden, William Dmitri; Brendlinger, Kurt; Brennan, Amelia Jean; Brenner, Lydia; Brenner, Richard; Bressler, Shikma; Bristow, Kieran; Bristow, Timothy Michael; Britton, Dave; Britzger, Daniel; Brochu, Frederic; Brock, Ian; Brock, Raymond; Bronner, Johanna; Brooijmans, Gustaaf; Brooks, Timothy; Brooks, William; Brosamer, Jacquelyn; Brost, Elizabeth; Brown, Jonathan; Bruckman de Renstrom, Pawel; Bruncko, Dusan; Bruneliere, Renaud; Bruni, Alessia; Bruni, Graziano; Bruschi, Marco; Bruscino, Nello; Bryngemark, Lene; Buanes, Trygve; Buat, Quentin; Buchholz, Peter; Buckley, Andrew; Buda, Stelian Ioan; Budagov, Ioulian; Buehrer, Felix; Bugge, Lars; Bugge, Magnar Kopangen; Bulekov, Oleg; Bullock, Daniel; Burckhart, Helfried; Burdin, Sergey; Burgard, Carsten Daniel; Burghgrave, Blake; Burke, Stephen; Burmeister, Ingo; Busato, Emmanuel; Büscher, Daniel; Büscher, Volker; Bussey, Peter; Butler, John; Butt, Aatif Imtiaz; Buttar, Craig; Butterworth, Jonathan; Butti, Pierfrancesco; Buttinger, William; Buzatu, Adrian; Buzykaev, Aleksey; Cabrera Urbán, Susana; Caforio, Davide; Cairo, Valentina; Cakir, Orhan; Calace, Noemi; Calafiura, Paolo; Calandri, Alessandro; Calderini, Giovanni; Calfayan, Philippe; Caloba, Luiz; Calvet, David; Calvet, Samuel; Camacho Toro, Reina; Camarda, Stefano; Camarri, Paolo; Cameron, David; Caminal Armadans, Roger; Campana, Simone; Campanelli, Mario; Campoverde, Angel; Canale, Vincenzo; Canepa, Anadi; Cano Bret, Marc; Cantero, Josu; Cantrill, Robert; Cao, Tingting; Capeans Garrido, Maria Del Mar; Caprini, Irinel; Caprini, Mihai; Capua, Marcella; Caputo, Regina; Cardarelli, Roberto; Cardillo, Fabio; Carli, Tancredi; Carlino, Gianpaolo; Carminati, Leonardo; Caron, Sascha; Carquin, Edson; Carrillo-Montoya, German D; Carter, Janet; Carvalho, João; Casadei, Diego; Casado, Maria Pilar; Casolino, Mirkoantonio; Castaneda-Miranda, Elizabeth; Castelli, Angelantonio; Castillo Gimenez, Victoria; Castro, Nuno Filipe; Catastini, Pierluigi; Catinaccio, Andrea; Catmore, James; Cattai, Ariella; Caudron, Julien; Cavaliere, Viviana; Cavalli, Donatella; Cavalli-Sforza, Matteo; Cavasinni, Vincenzo; Ceradini, Filippo; Cerio, Benjamin; Cerny, Karel; Santiago Cerqueira, Augusto; Cerri, Alessandro; Cerrito, Lucio; Cerutti, Fabio; Cerv, Matevz; Cervelli, Alberto; Cetin, Serkant Ali; Chafaq, Aziz; Chakraborty, Dhiman; Chalupkova, Ina; Chang, Philip; Chapman, John Derek; Charlton, Dave; Chau, Chav Chhiv; Chavez Barajas, Carlos Alberto; Cheatham, Susan; Chegwidden, Andrew; Chekanov, Sergei; Chekulaev, Sergey; Chelkov, Gueorgui; Chelstowska, Magda Anna; Chen, Chunhui; Chen, Hucheng; Chen, Karen; Chen, Liming; Chen, Shenjian; Chen, Xin; Chen, Ye; Cheng, Hok Chuen; Cheng, Yangyang; Cheplakov, Alexander; Cheremushkina, Evgenia; Cherkaoui El Moursli, Rajaa; Chernyatin, Valeriy; Cheu, Elliott; Chevalier, Laurent; Chiarella, Vitaliano; Chiarelli, Giorgio; Childers, John Taylor; Chiodini, Gabriele; Chisholm, Andrew; Chislett, Rebecca Thalatta; Chitan, Adrian; Chizhov, Mihail; Choi, Kyungeon; Chouridou, Sofia; Chow, Bonnie Kar Bo; Christodoulou, Valentinos; Chromek-Burckhart, Doris; Chudoba, Jiri; Chuinard, Annabelle Julia; Chwastowski, Janusz; Chytka, Ladislav; Ciapetti, Guido; Ciftci, Abbas Kenan; Cinca, Diane; Cindro, Vladimir; Cioara, Irina Antonela; Ciocio, Alessandra; Citron, Zvi Hirsh; Ciubancan, Mihai; Clark, Allan G; Clark, Brian Lee; Clark, Philip James; Clarke, Robert; Cleland, Bill; Clement, Christophe; Coadou, Yann; Cobal, Marina; Coccaro, Andrea; Cochran, James H; Coffey, Laurel; Cogan, Joshua Godfrey; Colasurdo, Luca; Cole, Brian; Cole, Stephen; Colijn, Auke-Pieter; Collot, Johann; Colombo, Tommaso; Compostella, Gabriele; Conde Muiño, Patricia; Coniavitis, Elias; Connell, Simon Henry; Connelly, Ian; Consonni, Sofia Maria; Consorti, Valerio; Constantinescu, Serban; Conta, Claudio; Conti, Geraldine; Conventi, Francesco; Cooke, Mark; Cooper, Ben; Cooper-Sarkar, Amanda; Cornelissen, Thijs; Corradi, Massimo; Corriveau, Francois; Corso-Radu, Alina; Cortes-Gonzalez, Arely; Cortiana, Giorgio; Costa, Giuseppe; Costa, María José; Costanzo, Davide; Côté, David; Cottin, Giovanna; Cowan, Glen; Cox, Brian; Cranmer, Kyle; Cree, Graham; Crépé-Renaudin, Sabine; Crescioli, Francesco; Cribbs, Wayne Allen; Crispin Ortuzar, Mireia; Cristinziani, Markus; Croft, Vince; Crosetti, Giovanni; Cuhadar Donszelmann, Tulay; Cummings, Jane; Curatolo, Maria; Cuthbert, Cameron; Czirr, Hendrik; Czodrowski, Patrick; D'Auria, Saverio; D'Onofrio, Monica; Da Cunha Sargedas De Sousa, Mario Jose; Da Via, Cinzia; Dabrowski, Wladyslaw; Dafinca, Alexandru; Dai, Tiesheng; Dale, Orjan; Dallaire, Frederick; Dallapiccola, Carlo; Dam, Mogens; Dandoy, Jeffrey Rogers; Dang, Nguyen Phuong; Daniells, Andrew Christopher; Danninger, Matthias; Dano Hoffmann, Maria; Dao, Valerio; Darbo, Giovanni; Darmora, Smita; Dassoulas, James; Dattagupta, Aparajita; Davey, Will; David, Claire; Davidek, Tomas; Davies, Eleanor; Davies, Merlin; Davison, Peter; Davygora, Yuriy; Dawe, Edmund; Dawson, Ian; Daya-Ishmukhametova, Rozmin; De, Kaushik; de Asmundis, Riccardo; De Benedetti, Abraham; De Castro, Stefano; De Cecco, Sandro; De Groot, Nicolo; de Jong, Paul; De la Torre, Hector; De Lorenzi, Francesco; De Nooij, Lucie; De Pedis, Daniele; De Salvo, Alessandro; De Sanctis, Umberto; De Santo, Antonella; De Vivie De Regie, Jean-Baptiste; Dearnaley, William James; Debbe, Ramiro; Debenedetti, Chiara; Dedovich, Dmitri; Deigaard, Ingrid; Del Peso, Jose; Del Prete, Tarcisio; Delgove, David; Deliot, Frederic; Delitzsch, Chris Malena; Deliyergiyev, Maksym; Dell'Acqua, Andrea; Dell'Asta, Lidia; Dell'Orso, Mauro; Della Pietra, Massimo; della Volpe, Domenico; Delmastro, Marco; Delsart, Pierre-Antoine; Deluca, Carolina; DeMarco, David; Demers, Sarah; Demichev, Mikhail; Demilly, Aurelien; Denisov, Sergey; Derendarz, Dominik; Derkaoui, Jamal Eddine; Derue, Frederic; Dervan, Paul; Desch, Klaus Kurt; Deterre, Cecile; Deviveiros, Pier-Olivier; Dewhurst, Alastair; Dhaliwal, Saminder; Di Ciaccio, Anna; Di Ciaccio, Lucia; Di Domenico, Antonio; Di Donato, Camilla; Di Girolamo, Alessandro; Di Girolamo, Beniamino; Di Mattia, Alessandro; Di Micco, Biagio; Di Nardo, Roberto; Di Simone, Andrea; Di Sipio, Riccardo; Di Valentino, David; Diaconu, Cristinel; Diamond, Miriam; Dias, Flavia; Diaz, Marco Aurelio; Diehl, Edward; Dietrich, Janet; Diglio, Sara; Dimitrievska, Aleksandra; Dingfelder, Jochen; Dita, Petre; Dita, Sanda; Dittus, Fridolin; Djama, Fares; Djobava, Tamar; Djuvsland, Julia Isabell; Barros do Vale, Maria Aline; Dobos, Daniel; Dobre, Monica; Doglioni, Caterina; Dohmae, Takeshi; Dolejsi, Jiri; Dolezal, Zdenek; Dolgoshein, Boris; Donadelli, Marisilvia; Donati, Simone; Dondero, Paolo; Donini, Julien; Dopke, Jens; Doria, Alessandra; Dova, Maria-Teresa; Doyle, Tony; Drechsler, Eric; Dris, Manolis; Dubreuil, Emmanuelle; Duchovni, Ehud; Duckeck, Guenter; Ducu, Otilia Anamaria; Duda, Dominik; Dudarev, Alexey; Duflot, Laurent; Duguid, Liam; Dührssen, Michael; Dunford, Monica; Duran Yildiz, Hatice; Düren, Michael; Durglishvili, Archil; Duschinger, Dirk; Dyndal, Mateusz; Eckardt, Christoph; Ecker, Katharina Maria; Edgar, Ryan Christopher; Edson, William; Edwards, Nicholas Charles; Ehrenfeld, Wolfgang; Eifert, Till; Eigen, Gerald; Einsweiler, Kevin; Ekelof, Tord; El Kacimi, Mohamed; Ellert, Mattias; Elles, Sabine; Ellinghaus, Frank; Elliot, Alison; Ellis, Nicolas; Elmsheuser, Johannes; Elsing, Markus; Emeliyanov, Dmitry; Enari, Yuji; Endner, Oliver Chris; Endo, Masaki; Erdmann, Johannes; Ereditato, Antonio; Ernis, Gunar; Ernst, Jesse; Ernst, Michael; Errede, Steven; Ertel, Eugen; Escalier, Marc; Esch, Hendrik; Escobar, Carlos; Esposito, Bellisario; Etienvre, Anne-Isabelle; Etzion, Erez; Evans, Hal; Ezhilov, Alexey; Fabbri, Laura; Facini, Gabriel; Fakhrutdinov, Rinat; Falciano, Speranza; Falla, Rebecca Jane; Faltova, Jana; Fang, Yaquan; Fanti, Marcello; Farbin, Amir; Farilla, Addolorata; Farooque, Trisha; Farrell, Steven; Farrington, Sinead; Farthouat, Philippe; Fassi, Farida; Fassnacht, Patrick; Fassouliotis, Dimitrios; Faucci Giannelli, Michele; Favareto, Andrea; Fayard, Louis; Federic, Pavol; Fedin, Oleg; Fedorko, Wojciech; Feigl, Simon; Feligioni, Lorenzo; Feng, Cunfeng; Feng, Eric; Feng, Haolu; Fenyuk, Alexander; Feremenga, Last; Fernandez Martinez, Patricia; Fernandez Perez, Sonia; Ferrando, James; Ferrari, Arnaud; Ferrari, Pamela; Ferrari, Roberto; Ferreira de Lima, Danilo Enoque; Ferrer, Antonio; Ferrere, Didier; Ferretti, Claudio; Ferretto Parodi, Andrea; Fiascaris, Maria; Fiedler, Frank; Filipčič, Andrej; Filipuzzi, Marco; Filthaut, Frank; Fincke-Keeler, Margret; Finelli, Kevin Daniel; Fiolhais, Miguel; Fiorini, Luca; Firan, Ana; Fischer, Adam; Fischer, Cora; Fischer, Julia; Fisher, Wade Cameron; Fitzgerald, Eric Andrew; Flaschel, Nils; Fleck, Ivor; Fleischmann, Philipp; Fleischmann, Sebastian; Fletcher, Gareth Thomas; Fletcher, Gregory; Fletcher, Rob Roy MacGregor; Flick, Tobias; Floderus, Anders; Flores Castillo, Luis; Flowerdew, Michael; Formica, Andrea; Forti, Alessandra; Fournier, Daniel; Fox, Harald; Fracchia, Silvia; Francavilla, Paolo; Franchini, Matteo; Francis, David; Franconi, Laura; Franklin, Melissa; Frate, Meghan; Fraternali, Marco; Freeborn, David; French, Sky; Friedrich, Felix; Froidevaux, Daniel; Frost, James; Fukunaga, Chikara; Fullana Torregrosa, Esteban; Fulsom, Bryan Gregory; Fusayasu, Takahiro; Fuster, Juan; Gabaldon, Carolina; Gabizon, Ofir; Gabrielli, Alessandro; Gabrielli, Andrea; Gach, Grzegorz; Gadatsch, Stefan; Gadomski, Szymon; Gagliardi, Guido; Gagnon, Pauline; Galea, Cristina; Galhardo, Bruno; Gallas, Elizabeth; Gallop, Bruce; Gallus, Petr; Galster, Gorm Aske Gram Krohn; Gan, KK; Gao, Jun; Gao, Yanyan; Gao, Yongsheng; Garay Walls, Francisca; Garberson, Ford; García, Carmen; García Navarro, José Enrique; Garcia-Sciveres, Maurice; Gardner, Robert; Garelli, Nicoletta; Garonne, Vincent; Gatti, Claudio; Gaudiello, Andrea; Gaudio, Gabriella; Gaur, Bakul; Gauthier, Lea; Gauzzi, Paolo; Gavrilenko, Igor; Gay, Colin; Gaycken, Goetz; Gazis, Evangelos; Ge, Peng; Gecse, Zoltan; Gee, Norman; Geerts, Daniël Alphonsus Adrianus; Geich-Gimbel, Christoph; Geisler, Manuel Patrice; Gemme, Claudia; Genest, Marie-Hélène; Gentile, Simonetta; George, Matthias; George, Simon; Gerbaudo, Davide; Gershon, Avi; Ghasemi, Sara; Ghazlane, Hamid; Giacobbe, Benedetto; Giagu, Stefano; Giangiobbe, Vincent; Giannetti, Paola; Gibbard, Bruce; Gibson, Stephen; Gilchriese, Murdock; Gillam, Thomas; Gillberg, Dag; Gilles, Geoffrey; Gingrich, Douglas; Giokaris, Nikos; Giordani, MarioPaolo; Giorgi, Filippo Maria; Giorgi, Francesco Michelangelo; Giraud, Pierre-Francois; Giromini, Paolo; Giugni, Danilo; Giuliani, Claudia; Giulini, Maddalena; Gjelsten, Børge Kile; Gkaitatzis, Stamatios; Gkialas, Ioannis; Gkougkousis, Evangelos Leonidas; Gladilin, Leonid; Glasman, Claudia; Glatzer, Julian; Glaysher, Paul; Glazov, Alexandre; Goblirsch-Kolb, Maximilian; Goddard, Jack Robert; Godlewski, Jan; Goldfarb, Steven; Golling, Tobias; Golubkov, Dmitry; Gomes, Agostinho; Gonçalo, Ricardo; Goncalves Pinto Firmino Da Costa, Joao; Gonella, Laura; González de la Hoz, Santiago; Gonzalez Parra, Garoe; Gonzalez-Sevilla, Sergio; Goossens, Luc; Gorbounov, Petr Andreevich; Gordon, Howard; Gorelov, Igor; Gorini, Benedetto; Gorini, Edoardo; Gorišek, Andrej; Gornicki, Edward; Goshaw, Alfred; Gössling, Claus; Gostkin, Mikhail Ivanovitch; Goujdami, Driss; Goussiou, Anna; Govender, Nicolin; Gozani, Eitan; Grabas, Herve Marie Xavier; Graber, Lars; Grabowska-Bold, Iwona; Gradin, Per Olov Joakim; Grafström, Per; Grahn, Karl-Johan; Gramling, Johanna; Gramstad, Eirik; Grancagnolo, Sergio; Gratchev, Vadim; Gray, Heather; Graziani, Enrico; Greenwood, Zeno Dixon; Gregersen, Kristian; Gregor, Ingrid-Maria; Grenier, Philippe; Griffiths, Justin; Grillo, Alexander; Grimm, Kathryn; Grinstein, Sebastian; Gris, Philippe Luc Yves; Grivaz, Jean-Francois; Grohs, Johannes Philipp; Grohsjean, Alexander; Gross, Eilam; Grosse-Knetter, Joern; Grossi, Giulio Cornelio; Grout, Zara Jane; Guan, Liang; Guenther, Jaroslav; Guescini, Francesco; Guest, Daniel; Gueta, Orel; Guido, Elisa; Guillemin, Thibault; Guindon, Stefan; Gul, Umar; Gumpert, Christian; Guo, Jun; Guo, Yicheng; Gupta, Shaun; Gustavino, Giuliano; Gutierrez, Phillip; Gutierrez Ortiz, Nicolas Gilberto; Gutschow, Christian; Guyot, Claude; Gwenlan, Claire; Gwilliam, Carl; Haas, Andy; Haber, Carl; Hadavand, Haleh Khani; Haddad, Nacim; Haefner, Petra; Hageböck, Stephan; Hajduk, Zbigniew; Hakobyan, Hrachya; Haleem, Mahsana; Haley, Joseph; Hall, David; Halladjian, Garabed; Hallewell, Gregory David; Hamacher, Klaus; Hamal, Petr; Hamano, Kenji; Hamilton, Andrew; Hamity, Guillermo Nicolas; Hamnett, Phillip George; Han, Liang; Hanagaki, Kazunori; Hanawa, Keita; Hance, Michael; Hanke, Paul; Hanna, Remie; Hansen, Jørgen Beck; Hansen, Jorn Dines; Hansen, Maike Christina; Hansen, Peter Henrik; Hara, Kazuhiko; Hard, Andrew; Harenberg, Torsten; Hariri, Faten; Harkusha, Siarhei; Harrington, Robert; Harrison, Paul Fraser; Hartjes, Fred; Hasegawa, Makoto; Hasegawa, Satoshi; Hasegawa, Yoji; Hasib, A; Hassani, Samira; Haug, Sigve; Hauser, Reiner; Hauswald, Lorenz; Havranek, Miroslav; Hawkes, Christopher; Hawkings, Richard John; Hawkins, Anthony David; Hayashi, Takayasu; Hayden, Daniel; Hays, Chris; Hays, Jonathan Michael; Hayward, Helen; Haywood, Stephen; Head, Simon; Heck, Tobias; Hedberg, Vincent; Heelan, Louise; Heim, Sarah; Heim, Timon; Heinemann, Beate; Heinrich, Lukas; Hejbal, Jiri; Helary, Louis; Hellman, Sten; Hellmich, Dennis; Helsens, Clement; Henderson, James; Henderson, Robert; Heng, Yang; Hengler, Christopher; Henrichs, Anna; Henriques Correia, Ana Maria; Henrot-Versille, Sophie; Herbert, Geoffrey Henry; Hernández Jiménez, Yesenia; Herrberg-Schubert, Ruth; Herten, Gregor; Hertenberger, Ralf; Hervas, Luis; Hesketh, Gavin Grant; Hessey, Nigel; Hetherly, Jeffrey Wayne; Hickling, Robert; Higón-Rodriguez, Emilio; Hill, Ewan; Hill, John; Hiller, Karl Heinz; Hillier, Stephen; Hinchliffe, Ian; Hines, Elizabeth; Hinman, Rachel Reisner; Hirose, Minoru; Hirschbuehl, Dominic; Hobbs, John; Hod, Noam; Hodgkinson, Mark; Hodgson, Paul; Hoecker, Andreas; Hoeferkamp, Martin; Hoenig, Friedrich; Hohlfeld, Marc; Hohn, David; Holmes, Tova Ray; Homann, Michael; Hong, Tae Min; Hooft van Huysduynen, Loek; Hopkins, Walter; Horii, Yasuyuki; Horton, Arthur James; Hostachy, Jean-Yves; Hou, Suen; Hoummada, Abdeslam; Howard, Jacob; Howarth, James; Hrabovsky, Miroslav; Hristova, Ivana; Hrivnac, Julius; Hryn'ova, Tetiana; Hrynevich, Aliaksei; Hsu, Catherine; Hsu, Pai-hsien Jennifer; Hsu, Shih-Chieh; Hu, Diedi; Hu, Qipeng; Hu, Xueye; Huang, Yanping; Hubacek, Zdenek; Hubaut, Fabrice; Huegging, Fabian; Huffman, Todd Brian; Hughes, Emlyn; Hughes, Gareth; Huhtinen, Mika; Hülsing, Tobias Alexander; Huseynov, Nazim; Huston, Joey; Huth, John; Iacobucci, Giuseppe; Iakovidis, Georgios; Ibragimov, Iskander; Iconomidou-Fayard, Lydia; Ideal, Emma; Idrissi, Zineb; Iengo, Paolo; Igonkina, Olga; Iizawa, Tomoya; Ikegami, Yoichi; Ikematsu, Katsumasa; Ikeno, Masahiro; Ilchenko, Iurii; Iliadis, Dimitrios; Ilic, Nikolina; Ince, Tayfun; Introzzi, Gianluca; Ioannou, Pavlos; Iodice, Mauro; Iordanidou, Kalliopi; Ippolito, Valerio; Irles Quiles, Adrian; Isaksson, Charlie; Ishino, Masaya; Ishitsuka, Masaki; Ishmukhametov, Renat; Issever, Cigdem; Istin, Serhat; Iturbe Ponce, Julia Mariana; Iuppa, Roberto; Ivarsson, Jenny; Iwanski, Wieslaw; Iwasaki, Hiroyuki; Izen, Joseph; Izzo, Vincenzo; Jabbar, Samina; Jackson, Brett; Jackson, Matthew; Jackson, Paul; Jaekel, Martin; Jain, Vivek; Jakobs, Karl; Jakobsen, Sune; Jakoubek, Tomas; Jakubek, Jan; Jamin, David Olivier; Jana, Dilip; Jansen, Eric; Jansky, Roland; Janssen, Jens; Janus, Michel; Jarlskog, Göran; Javadov, Namig; Javůrek, Tomáš; Jeanty, Laura; Jejelava, Juansher; Jeng, Geng-yuan; Jennens, David; Jenni, Peter; Jentzsch, Jennifer; Jeske, Carl; Jézéquel, Stéphane; Ji, Haoshuang; Jia, Jiangyong; Jiang, Yi; Jiggins, Stephen; Jimenez Pena, Javier; Jin, Shan; Jinaru, Adam; Jinnouchi, Osamu; Joergensen, Morten Dam; Johansson, Per; Johns, Kenneth; Jon-And, Kerstin; Jones, Graham; Jones, Roger; Jones, Tim; Jongmanns, Jan; Jorge, Pedro; Joshi, Kiran Daniel; Jovicevic, Jelena; Ju, Xiangyang; Jung, Christian; Jussel, Patrick; Juste Rozas, Aurelio; Kaci, Mohammed; Kaczmarska, Anna; Kado, Marumi; Kagan, Harris; Kagan, Michael; Kahn, Sebastien Jonathan; Kajomovitz, Enrique; Kalderon, Charles William; Kama, Sami; Kamenshchikov, Andrey; Kanaya, Naoko; Kaneti, Steven; Kantserov, Vadim; Kanzaki, Junichi; Kaplan, Benjamin; Kaplan, Laser Seymour; Kapliy, Anton; Kar, Deepak; Karakostas, Konstantinos; Karamaoun, Andrew; Karastathis, Nikolaos; Kareem, Mohammad Jawad; Karnevskiy, Mikhail; Karpov, Sergey; Karpova, Zoya; Karthik, Krishnaiyengar; Kartvelishvili, Vakhtang; Karyukhin, Andrey; Kashif, Lashkar; Kass, Richard; Kastanas, Alex; Kataoka, Yousuke; Kato, Chikuma; Katre, Akshay; Katzy, Judith; Kawagoe, Kiyotomo; Kawamoto, Tatsuo; Kawamura, Gen; Kazama, Shingo; Kazanin, Vassili; Keeler, Richard; Kehoe, Robert; Keller, John; Kempster, Jacob Julian; Keoshkerian, Houry; Kepka, Oldrich; Kerševan, Borut Paul; Kersten, Susanne; Keyes, Robert; Khalil-zada, Farkhad; Khandanyan, Hovhannes; Khanov, Alexander; Kharlamov, Alexey; Khoo, Teng Jian; Khovanskiy, Valery; Khramov, Evgeniy; Khubua, Jemal; Kido, Shogo; Kim, Hee Yeun; Kim, Shinhong; Kim, Young-Kee; Kimura, Naoki; Kind, Oliver Maria; King, Barry; King, Matthew; King, Samuel Burton; Kirk, Julie; Kiryunin, Andrey; Kishimoto, Tomoe; Kisielewska, Danuta; Kiss, Florian; Kiuchi, Kenji; Kivernyk, Oleh; Kladiva, Eduard; Klein, Matthew Henry; Klein, Max; Klein, Uta; Kleinknecht, Konrad; Klimek, Pawel; Klimentov, Alexei; Klingenberg, Reiner; Klinger, Joel Alexander; Klioutchnikova, Tatiana; Kluge, Eike-Erik; Kluit, Peter; Kluth, Stefan; Knapik, Joanna; Kneringer, Emmerich; Knoops, Edith; Knue, Andrea; Kobayashi, Aine; Kobayashi, Dai; Kobayashi, Tomio; Kobel, Michael; Kocian, Martin; Kodys, Peter; Koffas, Thomas; Koffeman, Els; Kogan, Lucy Anne; Kohlmann, Simon; Kohout, Zdenek; Kohriki, Takashi; Koi, Tatsumi; Kolanoski, Hermann; Koletsou, Iro; Komar, Aston; Komori, Yuto; Kondo, Takahiko; Kondrashova, Nataliia; Köneke, Karsten; König, Adriaan; Kono, Takanori; Konoplich, Rostislav; Konstantinidis, Nikolaos; Kopeliansky, Revital; Koperny, Stefan; Köpke, Lutz; Kopp, Anna Katharina; Korcyl, Krzysztof; Kordas, Kostantinos; Korn, Andreas; Korol, Aleksandr; Korolkov, Ilya; Korolkova, Elena; Kortner, Oliver; Kortner, Sandra; Kosek, Tomas; Kostyukhin, Vadim; Kotov, Vladislav; Kotwal, Ashutosh; Kourkoumeli-Charalampidi, Athina; Kourkoumelis, Christine; Kouskoura, Vasiliki; Koutsman, Alex; Kowalewski, Robert Victor; Kowalski, Tadeusz; Kozanecki, Witold; Kozhin, Anatoly; Kramarenko, Viktor; Kramberger, Gregor; Krasnopevtsev, Dimitriy; Krasny, Mieczyslaw Witold; Krasznahorkay, Attila; Kraus, Jana; Kravchenko, Anton; Kreiss, Sven; Kretz, Moritz; Kretzschmar, Jan; Kreutzfeldt, Kristof; Krieger, Peter; Krizka, Karol; Kroeninger, Kevin; Kroha, Hubert; Kroll, Joe; Kroseberg, Juergen; Krstic, Jelena; Kruchonak, Uladzimir; Krüger, Hans; Krumnack, Nils; Kruse, Amanda; Kruse, Mark; Kruskal, Michael; Kubota, Takashi; Kucuk, Hilal; Kuday, Sinan; Kuehn, Susanne; Kugel, Andreas; Kuger, Fabian; Kuhl, Andrew; Kuhl, Thorsten; Kukhtin, Victor; Kulchitsky, Yuri; Kuleshov, Sergey; Kuna, Marine; Kunigo, Takuto; Kupco, Alexander; Kurashige, Hisaya; Kurochkin, Yurii; Kus, Vlastimil; Kuwertz, Emma Sian; Kuze, Masahiro; Kvita, Jiri; Kwan, Tony; Kyriazopoulos, Dimitrios; La Rosa, Alessandro; La Rosa Navarro, Jose Luis; La Rotonda, Laura; Lacasta, Carlos; Lacava, Francesco; Lacey, James; Lacker, Heiko; Lacour, Didier; Lacuesta, Vicente Ramón; Ladygin, Evgueni; Lafaye, Remi; Laforge, Bertrand; Lagouri, Theodota; Lai, Stanley; Lambourne, Luke; Lammers, Sabine; Lampen, Caleb; Lampl, Walter; Lançon, Eric; Landgraf, Ulrich; Landon, Murrough; Lang, Valerie Susanne; Lange, J örn Christian; Lankford, Andrew; Lanni, Francesco; Lantzsch, Kerstin; Lanza, Agostino; Laplace, Sandrine; Lapoire, Cecile; Laporte, Jean-Francois; Lari, Tommaso; Lasagni Manghi, Federico; Lassnig, Mario; Laurelli, Paolo; Lavrijsen, Wim; Law, Alexander; Laycock, Paul; Lazovich, Tomo; Le Dortz, Olivier; Le Guirriec, Emmanuel; Le Menedeu, Eve; LeBlanc, Matthew Edgar; LeCompte, Thomas; Ledroit-Guillon, Fabienne Agnes Marie; Lee, Claire Alexandra; Lee, Shih-Chang; Lee, Lawrence; Lefebvre, Guillaume; Lefebvre, Michel; Legger, Federica; Leggett, Charles; Lehan, Allan; Lehmann Miotto, Giovanna; Lei, Xiaowen; Leight, William Axel; Leisos, Antonios; Leister, Andrew Gerard; Leite, Marco Aurelio Lisboa; Leitner, Rupert; Lellouch, Daniel; Lemmer, Boris; Leney, Katharine; Lenz, Tatjana; Lenzi, Bruno; Leone, Robert; Leone, Sandra; Leonidopoulos, Christos; Leontsinis, Stefanos; Leroy, Claude; Lester, Christopher; Levchenko, Mikhail; Levêque, Jessica; Levin, Daniel; Levinson, Lorne; Levy, Mark; Lewis, Adrian; Leyko, Agnieszka; Leyton, Michael; Li, Bing; Li, Haifeng; Li, Ho Ling; Li, Lei; Li, Liang; Li, Shu; Li, Yichen; Liang, Zhijun; Liao, Hongbo; Liberti, Barbara; Liblong, Aaron; Lichard, Peter; Lie, Ki; Liebal, Jessica; Liebig, Wolfgang; Limbach, Christian; Limosani, Antonio; Lin, Simon; Lin, Tai-Hua; Linde, Frank; Lindquist, Brian Edward; Linnemann, James; Lipeles, Elliot; Lipniacka, Anna; Lisovyi, Mykhailo; Liss, Tony; Lissauer, David; Lister, Alison; Litke, Alan; Liu, Bo; Liu, Dong; Liu, Hao; Liu, Jian; Liu, Jianbei; Liu, Kun; Liu, Lulu; Liu, Miaoyuan; Liu, Minghui; Liu, Yanwen; Livan, Michele; Lleres, Annick; Llorente Merino, Javier; Lloyd, Stephen; Lo Sterzo, Francesco; Lobodzinska, Ewelina; Loch, Peter; Lockman, William; Loebinger, Fred; Loevschall-Jensen, Ask Emil; Loginov, Andrey; Lohse, Thomas; Lohwasser, Kristin; Lokajicek, Milos; Long, Brian Alexander; Long, Jonathan; Long, Robin Eamonn; Looper, Kristina Anne; Lopes, Lourenco; Lopez Mateos, David; Lopez Paredes, Brais; Lopez Paz, Ivan; Lorenz, Jeanette; Lorenzo Martinez, Narei; Losada, Marta; Loscutoff, Peter; Lösel, Philipp Jonathan; Lou, XinChou; Lounis, Abdenour; Love, Jeremy; Love, Peter; Lu, Nan; Lubatti, Henry; Luci, Claudio; Lucotte, Arnaud; Luehring, Frederick; Lukas, Wolfgang; Luminari, Lamberto; Lundberg, Olof; Lund-Jensen, Bengt; Lynn, David; Lysak, Roman; Lytken, Else; Ma, Hong; Ma, Lian Liang; Maccarrone, Giovanni; Macchiolo, Anna; Macdonald, Calum Michael; Maček, Boštjan; Machado Miguens, Joana; Macina, Daniela; Madaffari, Daniele; Madar, Romain; Maddocks, Harvey Jonathan; Mader, Wolfgang; Madsen, Alexander; Maeda, Junpei; Maeland, Steffen; Maeno, Tadashi; Maevskiy, Artem; Magradze, Erekle; Mahboubi, Kambiz; Mahlstedt, Joern; Maiani, Camilla; Maidantchik, Carmen; Maier, Andreas Alexander; Maier, Thomas; Maio, Amélia; Majewski, Stephanie; Makida, Yasuhiro; Makovec, Nikola; Malaescu, Bogdan; Malecki, Pawel; Maleev, Victor; Malek, Fairouz; Mallik, Usha; Malon, David; Malone, Caitlin; Maltezos, Stavros; Malyshev, Vladimir; Malyukov, Sergei; Mamuzic, Judita; Mancini, Giada; Mandelli, Beatrice; Mandelli, Luciano; Mandić, Igor; Mandrysch, Rocco; Maneira, José; Manfredini, Alessandro; Manhaes de Andrade Filho, Luciano; Manjarres Ramos, Joany; Mann, Alexander; Manousakis-Katsikakis, Arkadios; Mansoulie, Bruno; Mantifel, Rodger; Mantoani, Matteo; Mapelli, Livio; March, Luis; Marchiori, Giovanni; Marcisovsky, Michal; Marino, Christopher; Marjanovic, Marija; Marley, Daniel; Marroquim, Fernando; Marsden, Stephen Philip; Marshall, Zach; Marti, Lukas Fritz; Marti-Garcia, Salvador; Martin, Brian Thomas; Martin, Tim; Martin, Victoria Jane; Martin dit Latour, Bertrand; Martinez, Mario; Martin-Haugh, Stewart; Martoiu, Victor Sorin; Martyniuk, Alex; Marx, Marilyn; Marzano, Francesco; Marzin, Antoine; Masetti, Lucia; Mashimo, Tetsuro; Mashinistov, Ruslan; Masik, Jiri; Maslennikov, Alexey; Massa, Ignazio; Massa, Lorenzo; Massol, Nicolas; Mastrandrea, Paolo; Mastroberardino, Anna; Masubuchi, Tatsuya; Mättig, Peter; Mattmann, Johannes; Maurer, Julien; Maxfield, Stephen; Maximov, Dmitriy; Mazini, Rachid; Mazza, Simone Michele; Mazzaferro, Luca; Mc Goldrick, Garrin; Mc Kee, Shawn Patrick; McCarn, Allison; McCarthy, Robert; McCarthy, Tom; McCubbin, Norman; McFarlane, Kenneth; Mcfayden, Josh; Mchedlidze, Gvantsa; McMahon, Steve; McPherson, Robert; Medinnis, Michael; Meehan, Samuel; Mehlhase, Sascha; Mehta, Andrew; Meier, Karlheinz; Meineck, Christian; Meirose, Bernhard; Mellado Garcia, Bruce Rafael; Meloni, Federico; Mengarelli, Alberto; Menke, Sven; Meoni, Evelin; Mercurio, Kevin Michael; Mergelmeyer, Sebastian; Mermod, Philippe; Merola, Leonardo; Meroni, Chiara; Merritt, Frank; Messina, Andrea; Metcalfe, Jessica; Mete, Alaettin Serhan; Meyer, Carsten; Meyer, Christopher; Meyer, Jean-Pierre; Meyer, Jochen; Meyer Zu Theenhausen, Hanno; Middleton, Robin; Miglioranzi, Silvia; Mijović, Liza; Mikenberg, Giora; Mikestikova, Marcela; Mikuž, Marko; Milesi, Marco; Milic, Adriana; Miller, David; Mills, Corrinne; Milov, Alexander; Milstead, David; Minaenko, Andrey; Minami, Yuto; Minashvili, Irakli; Mincer, Allen; Mindur, Bartosz; Mineev, Mikhail; Ming, Yao; Mir, Lluisa-Maria; Mitani, Takashi; Mitrevski, Jovan; Mitsou, Vasiliki A; Miucci, Antonio; Miyagawa, Paul; Mjörnmark, Jan-Ulf; Moa, Torbjoern; Mochizuki, Kazuya; Mohapatra, Soumya; Mohr, Wolfgang; Molander, Simon; Moles-Valls, Regina; Mönig, Klaus; Monini, Caterina; Monk, James; Monnier, Emmanuel; Montejo Berlingen, Javier; Monticelli, Fernando; Monzani, Simone; Moore, Roger; Morange, Nicolas; Moreno, Deywis; Moreno Llácer, María; Morettini, Paolo; Morgenstern, Marcus; Mori, Daniel; Morii, Masahiro; Morinaga, Masahiro; Morisbak, Vanja; Moritz, Sebastian; Morley, Anthony Keith; Mornacchi, Giuseppe; Morris, John; Mortensen, Simon Stark; Morton, Alexander; Morvaj, Ljiljana; Mosidze, Maia; Moss, Josh; Motohashi, Kazuki; Mount, Richard; Mountricha, Eleni; Mouraviev, Sergei; Moyse, Edward; Muanza, Steve; Mudd, Richard; Mueller, Felix; Mueller, James; Mueller, Ralph Soeren Peter; Mueller, Thibaut; Muenstermann, Daniel; Mullen, Paul; Mullier, Geoffrey; Murillo Quijada, Javier Alberto; Murray, Bill; Musheghyan, Haykuhi; Musto, Elisa; Myagkov, Alexey; Myska, Miroslav; Nachman, Benjamin Philip; Nackenhorst, Olaf; Nadal, Jordi; Nagai, Koichi; Nagai, Ryo; Nagai, Yoshikazu; Nagano, Kunihiro; Nagarkar, Advait; Nagasaka, Yasushi; Nagata, Kazuki; Nagel, Martin; Nagy, Elemer; Nairz, Armin Michael; Nakahama, Yu; Nakamura, Koji; Nakamura, Tomoaki; Nakano, Itsuo; Namasivayam, Harisankar; Naranjo Garcia, Roger Felipe; Narayan, Rohin; Naumann, Thomas; Navarro, Gabriela; Nayyar, Ruchika; Neal, Homer; Nechaeva, Polina; Neep, Thomas James; Nef, Pascal Daniel; Negri, Andrea; Negrini, Matteo; Nektarijevic, Snezana; Nellist, Clara; Nelson, Andrew; Nemecek, Stanislav; Nemethy, Peter; Nepomuceno, Andre Asevedo; Nessi, Marzio; Neubauer, Mark; Neumann, Manuel; Neves, Ricardo; Nevski, Pavel; Newman, Paul; Nguyen, Duong Hai; Nickerson, Richard; Nicolaidou, Rosy; Nicquevert, Bertrand; Nielsen, Jason; Nikiforou, Nikiforos; Nikiforov, Andriy; Nikolaenko, Vladimir; Nikolic-Audit, Irena; Nikolopoulos, Konstantinos; Nilsen, Jon Kerr; Nilsson, Paul; Ninomiya, Yoichi; Nisati, Aleandro; Nisius, Richard; Nobe, Takuya; Nomachi, Masaharu; Nomidis, Ioannis; Nooney, Tamsin; Norberg, Scarlet; Nordberg, Markus; Novgorodova, Olga; Nowak, Sebastian; Nozaki, Mitsuaki; Nozka, Libor; Ntekas, Konstantinos; Nunes Hanninger, Guilherme; Nunnemann, Thomas; Nurse, Emily; Nuti, Francesco; O'Brien, Brendan Joseph; O'grady, Fionnbarr; O'Neil, Dugan; O'Shea, Val; Oakham, Gerald; Oberlack, Horst; Obermann, Theresa; Ocariz, Jose; Ochi, Atsuhiko; Ochoa, Ines; Ochoa-Ricoux, Juan Pedro; Oda, Susumu; Odaka, Shigeru; Ogren, Harold; Oh, Alexander; Oh, Seog; Ohm, Christian; Ohman, Henrik; Oide, Hideyuki; Okamura, Wataru; Okawa, Hideki; Okumura, Yasuyuki; Okuyama, Toyonobu; Olariu, Albert; Olivares Pino, Sebastian Andres; Oliveira Damazio, Denis; Oliver Garcia, Elena; Olszewski, Andrzej; Olszowska, Jolanta; Onofre, António; Onyisi, Peter; Oram, Christopher; Oreglia, Mark; Oren, Yona; Orestano, Domizia; Orlando, Nicola; Oropeza Barrera, Cristina; Orr, Robert; Osculati, Bianca; Ospanov, Rustem; Otero y Garzon, Gustavo; Otono, Hidetoshi; Ouchrif, Mohamed; Ouellette, Eric; Ould-Saada, Farid; Ouraou, Ahmimed; Oussoren, Koen Pieter; Ouyang, Qun; Ovcharova, Ana; Owen, Mark; Owen, Rhys Edward; Ozcan, Veysi Erkcan; Ozturk, Nurcan; Pachal, Katherine; Pacheco Pages, Andres; Padilla Aranda, Cristobal; Pagáčová, Martina; Pagan Griso, Simone; Paganis, Efstathios; Paige, Frank; Pais, Preema; Pajchel, Katarina; Palacino, Gabriel; Palestini, Sandro; Palka, Marek; Pallin, Dominique; Palma, Alberto; Pan, Yibin; Panagiotopoulou, Evgenia; Pandini, Carlo Enrico; Panduro Vazquez, William; Pani, Priscilla; Panitkin, Sergey; Pantea, Dan; Paolozzi, Lorenzo; Papadopoulou, Theodora; Papageorgiou, Konstantinos; Paramonov, Alexander; Paredes Hernandez, Daniela; Parker, Michael Andrew; Parker, Kerry Ann; Parodi, Fabrizio; Parsons, John; Parzefall, Ulrich; Pasqualucci, Enrico; Passaggio, Stefano; Pastore, Fernanda; Pastore, Francesca; Pásztor, Gabriella; Pataraia, Sophio; Patel, Nikhul; Pater, Joleen; Pauly, Thilo; Pearce, James; Pearson, Benjamin; Pedersen, Lars Egholm; Pedersen, Maiken; Pedraza Lopez, Sebastian; Pedro, Rute; Peleganchuk, Sergey; Pelikan, Daniel; Penc, Ondrej; Peng, Cong; Peng, Haiping; Penning, Bjoern; Penwell, John; Perepelitsa, Dennis; Perez Codina, Estel; Pérez García-Estañ, María Teresa; Perini, Laura; Pernegger, Heinz; Perrella, Sabrina; Peschke, Richard; 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    2015-09-03

    Many extensions of the Standard Model predict the existence of charged heavy long-lived particles, such as $R$-hadrons or charginos. These particles, if produced at the Large Hadron Collider, should be moving non-relativistically and are therefore identifiable through the measurement of an anomalously large specific energy loss in the ATLAS pixel detector. Measuring heavy long-lived particles through their track parameters in the vicinity of the interaction vertex provides sensitivity to metastable particles with lifetimes from 0.6 ns to 30 ns. A search for such particles with the ATLAS detector at the Large Hadron Collider is presented, based on a data sample corresponding to an integrated luminosity of 18.4 fb$^{-1}$ of $pp$ collisions at $\\sqrt{s}$ = 8 TeV. No significant deviation from the Standard Model background expectation is observed, and lifetime-dependent upper limits on $R$-hadrons and chargino production are set. Gluino $R$-hadrons with 10 ns lifetime and masses up to 1185 GeV are excluded at 95%...

  17. Passing particle toroidal precession induced by electric field in a tokamak

    International Nuclear Information System (INIS)

    Andreev, V. V.; Ilgisonis, V. I.; Sorokina, E. A.

    2013-01-01

    Characteristics of a rotation of passing particles in a tokamak with radial electric field are calculated. The expression for time-averaged toroidal velocity of the passing particle induced by the electric field is derived. The electric-field-induced additive to the toroidal velocity of the passing particle appears to be much smaller than the velocity of the electric drift calculated for the poloidal magnetic field typical for the trapped particle. This quantity can even have the different sign depending on the azimuthal position of the particle starting point. The unified approach for the calculation of the bounce period and of the time-averaged toroidal velocity of both trapped and passing particles in the whole volume of plasma column is presented. The results are obtained analytically and are confirmed by 3D numerical calculations of the trajectories of charged particles

  18. Passing particle toroidal precession induced by electric field in a tokamak

    Energy Technology Data Exchange (ETDEWEB)

    Andreev, V. V. [Peoples' Friendship University of Russia, Ordzhonikidze St. 3, Moscow 117198 (Russian Federation); Ilgisonis, V. I.; Sorokina, E. A. [Peoples' Friendship University of Russia, Ordzhonikidze St. 3, Moscow 117198 (Russian Federation); NRC “Kurchatov Institute”, Kurchatov Sq. 1, Moscow 123182 (Russian Federation)

    2013-12-15

    Characteristics of a rotation of passing particles in a tokamak with radial electric field are calculated. The expression for time-averaged toroidal velocity of the passing particle induced by the electric field is derived. The electric-field-induced additive to the toroidal velocity of the passing particle appears to be much smaller than the velocity of the electric drift calculated for the poloidal magnetic field typical for the trapped particle. This quantity can even have the different sign depending on the azimuthal position of the particle starting point. The unified approach for the calculation of the bounce period and of the time-averaged toroidal velocity of both trapped and passing particles in the whole volume of plasma column is presented. The results are obtained analytically and are confirmed by 3D numerical calculations of the trajectories of charged particles.

  19. Aerosol nucleation induced by a high energy particle beam

    DEFF Research Database (Denmark)

    Enghoff, Martin Andreas Bødker; Pedersen, Jens Olaf Pepke; Uggerhøj, Ulrik I.

    2011-01-01

    We have studied sulfuric acid aerosol nucleation in an atmospheric pressure reaction chamber using a 580 MeV electron beam to ionize the volume of the reaction chamber. We find a clear contribution from ion-induced nucleation and consider this to be the first unambiguous observation of the ion......-effect on aerosol nucleation using a particle beam under conditions that resemble the Earth's atmosphere. By comparison with ionization using a gamma source we further show that the nature of the ionizing particles is not important for the ion-induced component of the nucleation. This implies that inexpensive...... ionization sources - as opposed to expensive accelerator beams - can be used for investigations of ion-induced nucleation....

  20. Electromagnetic production of Higgs bosons, SUSY particles, glueballs and mesons in ultrarelativistic heavy-ion collisions

    International Nuclear Information System (INIS)

    Greiner, M.; Soff, G.

    1992-12-01

    The electromagnetic creation of various exotic particles in ultrarelativistic heavy-ion collisions is discussed. The production of intermediate mass Higgs bosons of the minimal supersymmetric extension of the Standard Model is enhanced over the Standard Model Higgs boson formation for certain model parameter choices and as a consequence might be detectable at LCH and SSC. We also investigate the electromagnetic generation of supersymmetric fermions and bosons as well as glueballs, mesons and fermions. (orig.)

  1. Heavy ion induced genetic effects in mammalian cells. Final report

    International Nuclear Information System (INIS)

    Kiefer, J.; Brend'amour, M.; Casares, A.; Egenolf, R.; Gutermuth, F.; Ikpeme, S.E.; Koch, S.; Kost, M.; Loebrich, M.; Pross, H.D.; Russmann, C.; Schmidt, P.; Schneider, E.; Stoll, U.; Weber, K.J.

    2001-01-01

    DNA double-strand breaks (DSBs) are generally assumed to be the most relevant initial event producing radiation-induced cellular lethality, as well as mutations and transformations. The dependence of their formation on radiation quality has been recently reviewed. Contrary to earlier observations there seems to be now agreement that the RBE does not increase above unity with increasing LET in mammalian cells when conventional techniques are applied which are not able to resolve smaller fragments. If they are, however, included in the analysis maximum RBE values around 2 are obtained. The situation is different with yeast: An increased effectiveness for DSB induction has been reported with alpha particles, as well as for heavy ions. This may be due to differences in methods or to chromosomal structure, as discussed in more detail in this paper. DSB induction was measured for a LET range of 100 to 11500 keV/? m in yeast cells using pulsed field gel electrophoresis. Under the conditions applied the chromosomes of the yeast cells could be separated according to size allowing the direct quantification of the DSB yield by measuring the intensity of the largest chromosomes. The results demonstrate clearly that DSB induction in yeast depends on radiation quality. The derived cross-sections for DSB induction were also compared to those for cell inactivation determined in parallel experiments under identical irradiation conditions. (orig.)

  2. An effective method for detection and analysis of DNA damage induced by heavy-ion beams

    International Nuclear Information System (INIS)

    Kazama, Y.; Saito, H.; Fujiwara, M.; Matsuyama, T.; Hayashi, Y.; Ryuto, H.; Fukunishi, N.; Abe, T.

    2007-01-01

    We have developed an efficient system to detect and analyze DNA mutations induced by heavy-ion beams in Arabidopsis thaliana. In this system, a stable transgenic Arabidopsis line that constitutively expresses a yellow fluorescent protein (YFP) by a single-copy gene at a genomic locus was constructed and irradiated with heavy-ion beams. The YFP gene is a target of mutagenesis, and its loss of function or expression can easily be detected by the disappearance of YFP signals in planta under microscopy. With this system, a sup(12)Csup(6+)- induced mutant with single deletion and multiple base changes was isolated

  3. Heavy baryons in the heavy quark effective theory

    International Nuclear Information System (INIS)

    Koerner, J.G.; Thompson, G.

    1991-10-01

    We give a mini-review of recent results on current-induced transitions between heavy baryons (and between heavy and light baryons) in the light of the new spin and flavour symmetries of the Heavy Quark Effective Theory (HQET). We discuss the structure of the 1/m corrections to the heavy mass limit and outline a diagrammatic proof that there are no 0(1/m) correction to the Voloshin-Shifman normalization condition at zero recoil. (orig.)

  4. In vitro neurotoxic effects of 1 GeV/n iron particles assessed in retinal explants.

    Science.gov (United States)

    Vazquez, M E; Kirk, E

    2000-01-01

    The heavy ion component of the cosmic radiation remains problematic to the assessment of risk in manned space flight. The biological effectiveness of HZE particles has yet to be established, particularly with regard to nervous tissue. Using heavy ions accelerated at the AGS of Brookhaven National Laboratory, we study the neurotoxic effects of iron particles. We exposed retinal explants, taken from chick embryos, to determine the dose response relationships for neurite outgrowth. Morphometric techniques were used to evaluate the in vitro effects of 1 GeV/a iron particles (LET 148 keV/micrometer). Iron particles produced a dose-dependent reduction of neurite outgrowth with a maximal effect achieved with a dose of 100 cGy. Doses as low as 10-50 cGy were able to induce reductions of the neurite outgrowth as compared to the control group. Neurite generation is a more sensitive parameter than neurite elongation, suggesting different mechanism of radiation damage in our model. These results showed that low doses/fluences of iron particles could impair the retinal ganglion cells' capacity to generate neurites indicating the highly neurotoxic capability of this heavy charged particle.

  5. Effects of heavy ion radiation on the brain vascular system and embryonic development

    Science.gov (United States)

    Yang, T. C.; Tobias, C. A.

    Using neonatal rats as a model system, we investigated the response of the brain vascular system to ionizing radiation and found that distinct petechial hemorrages developed in the cerebral cortex within a few hours after irradiation, reached a maximum about 13 to 24 hours, and decreased exponentially with time. No brain hemorrhage was found in neonatal rats 12 days after irradiation. Our experimental results indicate that a dose of a few hundred rad of X rays can induce a significant number of hemorrhages in the brain, and the number of lesions increases exponentially with dose. Heavy ions induce more hemorrhages than X rays for a given dose, and the RBE for 670 MeV/u neon particles ranges from about 2.0 for low doses to about 1.4 for high doses. A histological study on the hemorrhages indicates that a large number of red blood cells leak from the blood vessels. The radiation-induced hemorrhages may be a result of some capillary membrane damages or reproductive death of some blood vessel epithelial cells. The fast onset of hemorrhage after irradiation suggests that some membrane damage may be involved. The effect of heavy-ion radiation on the embryonic development was studied with energetic iron particles. Pregnant mice were whole-body irradiated with 600 MeV/u iron particles on day 6 of gestation and were sacrificed 12 days after irradiation. Various physical abnormalities were observed, and embryos irradiated with 1 rad iron particles showed retardation of body development.

  6. Anisotropic flow studies with identified particles with ALICE: a tool to probe different stages of a heavy-ion collision

    CERN Multimedia

    CERN. Geneva

    2017-01-01

    Anisotropic flow studies play a crucial role in the characterization of the nature of the quark gluon plasma (QGP) created in collisions of heavy ions at ultra-relativistic energies. These studies rely on measuring the coefficients vn of the Fourier expansion of the azimuthal particle distribution. They have been essential in establishing that the QGP is a strongly coupled, almost perfect fluid. In this seminar, I review the latest results from measurements of elliptic (v2), triangular (v3), quadrangular (v4) and pentagonal (v5) flow of identified particles at the LHC measured with ALICE. I will discuss how these results allow us to gain insight into the transport properties of the QGP and the initial conditions of a heavy-ion collision. In addition, they reveal the role of different hadronisation mechanisms as well as the highly dissipative hadronic rescattering phase to the development of vn.

  7. Search for Stable Heavy Charged Particles in $e^+ e^-$ Collisions at $\\sqrt{s}$ = 130-136, 161 and 172 GeV

    CERN Document Server

    Abreu, P; Adye, T; Ajinenko, I; Alekseev, G D; Alemany, R; Allport, P P; Almehed, S; Amaldi, Ugo; Amato, S; Andreazza, A; Andrieux, M L; Antilogus, P; Apel, W D; Åsman, B; Augustin, J E; Augustinus, A; Baillon, Paul; Bambade, P; Barão, F; Barbi, M S; Barbiellini, Guido; Bardin, Dimitri Yuri; Barker, G; Baroncelli, A; Bärring, O; Barrio, J A; Bartl, Walter; Bates, M J; Battaglia, Marco; Baubillier, M; Baudot, J; Becks, K H; Begalli, M; Beillière, P; Belokopytov, Yu A; Belous, K S; Benvenuti, Alberto C; Berggren, M; Bertini, D; Bertrand, D; Besançon, M; Bianchi, F; Bigi, M; Bilenky, S M; Billoir, P; Bizouard, M A; Bloch, D; Blume, M; Bolognese, T; Bonesini, M; Bonivento, W; Booth, P S L; Borisov, G; Bosio, C; Botner, O; Boudinov, E; Bouquet, B; Bourdarios, C; Bowcock, T J V; Bozzo, M; Branchini, P; Brand, K D; Brenke, T; Brenner, R A; Bricman, C; Brown, R C A; Brückman, P; Brunet, J M; Bugge, L; Buran, T; Burgsmüller, T; Buschmann, P; Cabrera, S; Caccia, M; Calvi, M; Camacho-Rozas, A J; Camporesi, T; Canale, V; Canepa, M; Cankocak, K; Cao, F; Carena, F; Carroll, L; Caso, Carlo; Castillo-Gimenez, M V; Cattai, A; Cavallo, F R; Chabaud, V; Charpentier, P; Chaussard, L; Checchia, P; Chelkov, G A; Chen, M; Chierici, R; Chliapnikov, P V; Chochula, P; Chorowicz, V; Cindro, V; Collins, P; Contri, R; Cortina, E; Cosme, G; Cossutti, F; Cowell, J H; Crawley, H B; Crennell, D J; Crosetti, G; Cuevas-Maestro, J; Czellar, S; Dahl-Jensen, Erik; Dahm, J; D'Almagne, B; Dam, M; Damgaard, G; Dauncey, P D; Davenport, Martyn; Da Silva, W; Defoix, C; Deghorain, A; Della Ricca, G; Delpierre, P A; Demaria, N; De Angelis, A; de Boer, Wim; De Brabandere, S; De Clercq, C; La Vaissière, C de; De Lotto, B; De Min, A; De Paula, L S; De Saint-Jean, C; Dijkstra, H; Di Ciaccio, Lucia; Di Diodato, A; Djama, F; Djannati, A; Dolbeau, J; Doroba, K; Dracos, M; Drees, J; Drees, K A; Dris, M; Durand, J D; Edsall, D M; Ehret, R; Eigen, G; Ekelöf, T J C; Ekspong, Gösta; Elsing, M; Engel, J P; Erzen, B; Espirito-Santo, M C; Falk, E; Fassouliotis, D; Feindt, Michael; Fenyuk, A; Ferrer, A; Fichet, S; Filippas-Tassos, A; Firestone, A; Fischer, P A; Föth, H; Fokitis, E; Fontanelli, F; Formenti, F; Franek, B J; Frenkiel, P; Fries, D E C; Frodesen, A G; Frühwirth, R; Fulda-Quenzer, F; Fuster, J A; Galloni, A; Gamba, D; Gandelman, M; García, C; García, J; Gaspar, C; Gasparini, U; Gavillet, P; Gazis, E N; Gelé, D; Gerber, J P; Gerdyukov, L N; Gokieli, R; Golob, B; Gopal, Gian P; Gorn, L; Górski, M; Guz, Yu; Gracco, Valerio; Graziani, E; Green, C; Grefrath, A; Gris, P; Grosdidier, G; Grzelak, K; Gumenyuk, S A; Gunnarsson, P; Günther, M; Guy, J; Hahn, F; Hahn, S; Hajduk, Z; Hallgren, A; Hamacher, K; Harris, F J; Hedberg, V; Henriques, R P; Hernández, J J; Herquet, P; Herr, H; Hessing, T L; Heuser, J M; Higón, E; Hilke, Hans Jürgen; Hill, T S; Holmgren, S O; Holt, P J; Holthuizen, D J; Hoorelbeke, S; Houlden, M A; Hrubec, Josef; Huet, K; Hultqvist, K; Jackson, J N; Jacobsson, R; Jalocha, P; Janik, R; Jarlskog, C; Jarlskog, G; Jarry, P; Jean-Marie, B; Johansson, E K; Jönsson, L B; Jönsson, P E; Joram, Christian; Juillot, P; Kaiser, M; Kapusta, F; Karafasoulis, K; Karlsson, M; Karvelas, E; Katsanevas, S; Katsoufis, E C; Keränen, R; Khokhlov, Yu A; Khomenko, B A; Khovanskii, N N; King, B J; Kjaer, N J; Klapp, O; Klein, H; Klovning, A; Kluit, P M; Kokkinias, P; Konoplyannikov, A K; Koratzinos, M; Korcyl, K; Kostyukhin, V; Kourkoumelis, C; Kuznetsov, O; Krammer, Manfred; Kreuter, C; Kronkvist, I J; Krumshtein, Z; Krupinski, W; Kubinec, P; Kucewicz, W; Kurvinen, K L; Lacasta, C; Laktineh, I; Lamsa, J; Lanceri, L; Lane, D W; Langefeld, P; Laugier, J P; Lauhakangas, R; Leder, Gerhard; Ledroit, F; Lefébure, V; Legan, C K; Leitner, R; Lemonne, J; Lenzen, Georg; Lepeltier, V; Lesiak, T; Libby, J; Liko, D; Lindner, R; Lipniacka, A; Lippi, I; Lörstad, B; Loken, J G; López, J M; Loukas, D; Lutz, P; Lyons, L; MacNaughton, J N; Maehlum, G; Mahon, J R; Malmgren, T G M; Malychev, V; Mandl, F; Marco, J; Marco, R P; Maréchal, B; Margoni, M; Marin, J C; Mariotti, C; Markou, A; Martínez-Rivero, C; Martínez-Vidal, F; Martí i García, S; Matorras, F; Matteuzzi, C; Matthiae, Giorgio; Mazzucato, M; McCubbin, M L; McKay, R; McNulty, R; Medbo, J; Merk, M; Meroni, C; Meyer, S; Meyer, W T; Michelotto, M; Migliore, E; Mirabito, L; Mitaroff, Winfried A; Mjörnmark, U; Moa, T; Møller, R; Mönig, K; Monge, M R; Morettini, P; Müller, H; Münich, K; Mulders, M; Mundim, L M; Murray, W J; Muryn, B; Myatt, Gerald; Naraghi, F; Navarria, Francesco Luigi; Navas, S; Nawrocki, K; Negri, P; Némécek, S; Neumann, W; Neumeister, N; Nicolaidou, R; Nielsen, B S; Nieuwenhuizen, M; Nikolaenko, V; Niss, P; Nomerotski, A; Normand, Ainsley; Novák, M; Oberschulte-Beckmann, W; Obraztsov, V F; Olshevskii, A G; Onofre, A; Orava, Risto; Österberg, K; Ouraou, A; Paganini, P; Paganoni, M; Pagès, P; Pain, R; Palka, H; Papadopoulou, T D; Papageorgiou, K; Pape, L; Parkes, C; Parodi, F; Passeri, A; Pegoraro, M; Peralta, L; Pernicka, Manfred; Perrotta, A; Petridou, C; Petrolini, A; Phillips, H T; Piana, G; Pierre, F; Pimenta, M; Podobnik, T; Podobrin, O; Pol, M E; Polok, G; Poropat, P; Pozdnyakov, V; Privitera, P; Pukhaeva, N; Pullia, Antonio; Radojicic, D; Ragazzi, S; Rahmani, H; Rames, J; Ratoff, P N; Read, A L; Reale, M; Rebecchi, P; Redaelli, N G; Regler, Meinhard; Reid, D; Reinhardt, R; Renton, P B; Resvanis, L K; Richard, F; Richardson, J; Rídky, J; Rinaudo, G; Ripp, I; Romero, A; Roncagliolo, I; Ronchese, P; Roos, L; Rosenberg, E I; Roudeau, Patrick; Rovelli, T; Ruhlmann-Kleider, V; Ruiz, A; Rybicki, K; Saarikko, H; Sacquin, Yu; Sadovskii, A; Sahr, O; Sajot, G; Salt, J; Sánchez, J; Sannino, M; Schimmelpfennig, M; Schneider, H; Schwickerath, U; Schyns, M A E; Sciolla, G; Scuri, F; Seager, P; Sedykh, Yu; Segar, A M; Seitz, A; Sekulin, R L; Serbelloni, L; Shellard, R C; Siegrist, P; Silvestre, R; Simonetti, S; Simonetto, F; Sissakian, A N; Sitár, B; Skaali, T B; Smadja, G; Smirnov, N; Smirnova, O G; Smith, G R; Solovyanov, O; Sosnowski, R; Souza-Santos, D; Spassoff, Tz; Spiriti, E; Sponholz, P; Squarcia, S; Stampfer, D; Stanescu, C; Stanic, S; Stapnes, Steinar; Stavitski, I; Stevenson, K; Stocchi, A; Strauss, J; Strub, R; Stugu, B; Szczekowski, M; Szeptycka, M; Tabarelli de Fatis, T; Tavernet, J P; Chernyaev, E; Thomas, J; Tilquin, A; Timmermans, J; Tkatchev, L G; Todorov, T; Todorova, S; Toet, D Z; Tomaradze, A G; Tomé, B; Tonazzo, A; Tortora, L; Tranströmer, G; Treille, D; Tristram, G; Trombini, A; Troncon, C; Tsirou, A L; Turluer, M L; Tyapkin, I A; Tyndel, M; Tzamarias, S; Überschär, B; Ullaland, O; Uvarov, V; Valenti, G; Vallazza, E; Van der Velde, C; van Apeldoorn, G W; van Dam, P; Van Doninck, W K; Van Eldik, J; Van Lysebetten, A; Vassilopoulos, N; Vegni, G; Ventura, L; Venus, W A; Verbeure, F; Verlato, M; Vertogradov, L S; Vilanova, D; Vincent, P; Vitale, L; Vodopyanov, A S; Vrba, V; Wahlen, H; Walck, C; Weierstall, M; Weilhammer, Peter; Weiser, C; Wetherell, Alan M; Wicke, D; Wickens, J H; Wielers, M; Wilkinson, G R; Williams, W S C; Winter, M; Witek, M; Wlodek, T; Woschnagg, K; Yip, K; Yushchenko, O P; Zach, F; Zaitsev, A; Zalewska-Bak, A; Zalewski, Piotr; Zavrtanik, D; Zevgolatakos, E; Zimin, N I; Zito, M; Zontar, D; Zucchelli, G C; Zumerle, G

    1997-01-01

    A search for stable or long-lived heavy charged particles in $e^+e^-$ interactions at energies of 130-136, 161 and 172 GeV has been performed using the data taken by the DELPHI experiment at LEP. The search is based on particle identification provided by the Time Projection Chamber and the Ring Imaging Cherenkov detector. Upper limits at 95\\% confidence level are derived on the cross-section for heavy long-lived pair-produced charge $\\pm e$ and $\\pm 2/3e$ particles in the range of 0.4-2.3 pb for masses from 45 to 84 GeV/$c^2$. Within supersymmetric extensions of the Standard Model, long-lived charginos with masses from 45 to 84 (80)~GeV/$c^2$ for high (low) sneutrino masses can be excluded at 95\\% confidence level. %Mass limits for long-lived sleptons are obtained. %For selectrons no general mass limits can be given. Left-handed (right-handed) long-lived or stable smuons and staus with masses between 45 and 68 (65)~GeV/$c^2$ can be excluded at 95\\% confidence level.

  8. Heavy-ion research at the tandem and superconducting linac accelerators

    International Nuclear Information System (INIS)

    Anon.

    1980-01-01

    The heavy-ion research program at the Argonne Physics Division is principally aimed at the study of nuclear structure and its manifestation in heavy-ion induced nuclear reactions. In order to extract information on nuclear structure, measurements with high precision often need to be performed. Such measurements are now carried out at the tandem-linac accelerator over a wide energy range. The investigation of high-spin states near the yrast line has provided much new information on the behavior of nuclei at high angular momentum. Argonne work has concentrated on nuclei where high-spin isomers, the so-called yrast traps, are prevalent. The resonance effects observed previously in the 24 Mg( 16 O, 12 C) 28 Si reactions have been further explored through both additional measurements and a new quantitative method of analysis. The measurements were extended in energy and angular range and to various exit channels as well as similar systems. Several measurements were performed to investigate the reaction mechanisms in heavy-ion induced reactions and to map out the distribution of reaction strength as a function of energy and target-projectile masses energy regions previously not accessible. The behavior of the quasi- and deep-inelastic reaction cross sections was studied as a function of energy for medium-heavy systems, the production of inclusive alpha-particle yields for 16 O beams at energies E/A greater than or equal to 5 MeV/nucleon, and excitation functions, mass and kinetic energy distributions for heavy-ion induced fusion-fission reactions

  9. Optically induced rotation of Rayleigh particles by vortex beams with different states of polarization

    International Nuclear Information System (INIS)

    Li, Manman; Yan, Shaohui; Yao, Baoli; Liang, Yansheng; Lei, Ming; Yang, Yanlong

    2016-01-01

    Optical vortex beams carry optical orbital angular momentum (OAM) and can induce an orbital motion of trapped particles in optical trapping. We show that the state of polarization (SOP) of vortex beams will affect the details of this optically induced orbital motion to some extent. Numerical results demonstrate that focusing the vortex beams with circular, radial or azimuthal polarizations can induce a uniform orbital motion on a trapped Rayleigh particle, while in the focal field of the vortex beam with linear polarization the particle experiences a non-uniform orbital motion. Among the formers, the vortex beam with circular polarization induces a maximum optical torque on the particle. Furthermore, by varying the topological charge of the vortex beams, the vortex beam with circular polarization gives rise to an optimum torque superior to those given by the other three vortex beams. These facts suggest that the circularly polarized vortex beam is more suitable for rotating particles. - Highlights: • States of polarization of vortex beams affect the optically induced orbital motion of particles. • The dependences of the force and orbital torque on the topological charge, the size and the absorptivity of particles were calculated. • Focused vortex beams with circular, radial or azimuthal polarizations induce a uniform orbital motion on particles. • Particles experience a non-uniform orbital motion in the focused linearly polarized vortex beam. • The circularly polarized vortex beam is a superior candidate for rotating particles.

  10. Heavy baryons

    International Nuclear Information System (INIS)

    Koerner, J.G.

    1994-06-01

    We review the experimental and theoretical status of baryons containing one heavy quark. The charm and bottom baryon states are classified and their mass spectra are listed. The appropriate theoretical framework for the description of heavy baryons is the Heavy Quark Effective Theory, whose general ideas and methods are introduced and illustrated in specific examples. We present simple covariant expressions for the spin wave functions of heavy baryons including p-wave baryons. The covariant spin wave functions are used to determine the Heavy Quark Symmetry structure of flavour-changing current-induced transitions between heavy baryons as well as one-pion and one-photon transitions between heavy baryons of the same flavour. We discuss 1/m Q corrections to the current-induced transitions as well as the structure of heavy to light baryon transitions. Whenever possible we attempt to present numbers to compare with experiment by making use of further model-dependent assumptions as e.g. the constituent picture for light quarks. We highlight recent advances in the theoretical understanding of the inclusive decays of hadrons containing one heavy quark including polarization. For exclusive semileptonic decays we discuss rates, angular decay distributions and polarization effects. We provide an update of the experimental and theoretical status of lifetimes of heavy baryons and of exclusive nonleptonic two body decays of charm baryons. (orig.)

  11. Nuclei at the limits of particle stability

    International Nuclear Information System (INIS)

    Mueller, A.C.

    1993-01-01

    The properties and synthesis of nuclei at the limits of particle stability are reviewed. Nuclear reactions were induced and studied by means of the 'exotic' nuclear beams, i.e. beams of radioactive drip-line nuclei. The beams are mostly generated in heavy-ion projectile fragmentation. The cases of both neutron-rich and proton-rich nuclei are discussed. (K.A.) 270 refs.; 13 figs.; 1 tab

  12. Influence of Magnolol on the bystander effect induced by alpha-particle irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Wong, T.P.W.; Law, Y.L. [Department of Physics and Materials Science, City University of Hong Kong, Tat Chee Avenue, Kowloon Tong (Hong Kong); Tse, A.K.W.; Fong, W.F. [Research and Development Division, School of Chinese Medicine, Hong Kong Baptist University, Baptist University Road, Kowloon Tong (Hong Kong); Yu, K.N. [Department of Physics and Materials Science, City University of Hong Kong, Tat Chee Avenue, Kowloon Tong (Hong Kong)], E-mail: peter.yu@cityu.edu.hk

    2010-04-15

    In this work, the influence of Magnolol on the bystander effect in alpha-particle irradiated Chinese hamster ovary (CHO) cells was examined. The bystander effect was studied through medium transfer experiments. Cytokinesis-block micronucleus (CBMN) assay was performed to quantify the chromosome damage induced by alpha-particle irradiation. Our results showed that the alpha-particle induced micronuclei (MN) frequencies were suppressed with the presence of Magnolol.

  13. Heavy color-octet particles at the LHC

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Chien-Yi [Department of Physics, Brookhaven National Laboratory,Upton, NY 11973 (United States); Freitas, Ayres; Han, Tao [PITTsburgh Particle physics, Astrophysics, and Cosmology Center (PITT PACC),Department of Physics & Astronomy, University of Pittsburgh, Pittsburgh, PA 15260 (United States); Lee, Keith S.M. [Perimeter Institute for Theoretical Physics,Waterloo, ON N2L 2Y5 (Canada); Department of Physics & Astronomy, University of Waterloo,Waterloo, ON N2L 3G1 (Canada)

    2015-05-26

    Many new-physics models, especially those with a color-triplet top-quark partner, contain a heavy color-octet state. The “naturalness” argument for a light Higgs boson requires that the color-octet state be not much heavier than a TeV, and thus it can be pair-produced with large cross sections at high-energy hadron colliders. It may decay preferentially to a top quark plus a top partner, which subsequently decays to a top quark plus a color-singlet state. This singlet can serve as a WIMP dark-matter candidate. Such decay chains lead to a spectacular signal of four top quarks plus missing energy. We pursue a general categorization of the color-octet states and their decay products according to their spin and gauge quantum numbers. We review the current bounds on the new states at the LHC and study the expected discovery reach at the 8-TeV and 14-TeV runs. We also present the production rates at a future 100-TeV hadron collider, where the cross sections will be many orders of magnitude greater than at the 14-TeV LHC. Furthermore, we explore the extent to which one can determine the color octet’s mass, spin, and chiral couplings. Finally, we propose a test to determine whether the fermionic color octet is a Majorana particle.

  14. Different particle determinants induce apoptosis and cytokine release in primary alveolar macrophage cultures

    Directory of Open Access Journals (Sweden)

    Schwarze Per E

    2006-06-01

    Full Text Available Abstract Background Particles are known to induce both cytokine release (MIP-2, TNF-α, a reduction in cell viability and an increased apoptosis in alveolar macrophages. To examine whether these responses are triggered by the same particle determinants, alveolar macrophages were exposed in vitro to mineral particles of different physical-chemical properties. Results The crystalline particles of the different stone types mylonite, gabbro, basalt, feldspar, quartz, hornfels and fine grain syenite porphyr (porphyr, with a relatively equal size distribution (≤ 10 μm, but different chemical/mineral composition, all induced low and relatively similar levels of apoptosis. In contrast, mylonite and gabbro induced a marked MIP-2 response compared to the other particles. For particles of smaller size, quartz (≤ 2 μm seemed to induce a somewhat stronger apoptotic response than even smaller quartz (≤ 0.5 μm and larger quartz (≤ 10 μm in relation to surface area, and was more potent than hornfels and porphyr (≤ 2 μm. The reduction in cell viability induced by quartz of the different sizes was roughly similar when adjusted to surface area. With respect to cytokines, the release was more marked after exposure to quartz ≤ 0.5 μm than to quartz ≤ 2 μm and ≤ 10 μm. Furthermore, hornfels (≤ 2 μm was more potent than the corresponding hornfels (≤ 10 μm and quartz (≤ 2 μm to induce cytokine responses. Pre-treatment of hornfels and quartz particles ≤ 2 μm with aluminium lactate, to diminish the surface reactivity, did significantly reduce the MIP-2 response to hornfels. In contrast, the apoptotic responses to the particles were not affected. Conclusion These results indicate that different determinants of mineral/stone particles are critical for inducing cytokine responses, reduction in cell viability and apoptosis in alveolar macrophages. The data suggest that the particle surface reactivity was critical for cytokine responses

  15. Tumor necrosis factor is not required for particle-induced genotoxicity and pulmonary inflammation

    Energy Technology Data Exchange (ETDEWEB)

    Saber, Anne T.; Bornholdt, Jette; Dybdahl, Marianne; Sharma, Anoop K.; Vogel, Ulla; Wallin, Haakan [National Institute of Occupational Health, Copenhagen (Denmark); Loft, Steffen [Copenhagen University, Institute of Public Health, Copenhagen (Denmark)

    2005-03-01

    Particle-induced carcinogenicity is not well understood, but might involve inflammation. The proinflammatory cytokine tumor necrosis factor (TNF) is considered to be an important mediator in inflammation. We investigated its role in particle-induced inflammation and DNA damage in mice with and without TNF signaling. TNF-/- mice and TNF+/+ mice were exposed by inhalation to 20 mg m{sup -3} carbon black (CB), 20 mg m{sup -3} diesel exhaust particles (DEP), or filtered air for 90 min on each of four consecutive days. DEP, but not CB particles, induced infiltration of neutrophilic granulocutes into the lung lining fluid (by the cellular fraction in the bronchoalveolar lavage fluid), and both particle types induced interleukin-6 mRNA in the lung tissue. Surprisingly, TNF-/- mice were intact in these inflammatory responses. There were more DNA strand breaks in the BAL cells of DEP-exposed TNF-/- mice and CB-exposed mice compared with the air-exposed mice. Thus, the CB-induced DNA damage in BAL-cells was independent of neutrophil infiltration. The data indicate that an inflammatory response was not a prerequisite for DNA damage, and TNF was not required for the induction of inflammation by DEP and CB particles. (orig.)

  16. Effect of position and momentum constraints on charge distribution in heavy-ion collisions

    International Nuclear Information System (INIS)

    Rajni; Kumar, Suneel

    2012-01-01

    The rich phenomenology of multifragmentation has been widely explored after two decades of its discovery. It has been experimentally shown that in one single heavy ion collision many intermediate mass fragments (IMFs) are produced, where IMFs are defined as fragments with 5 ≤ A ≤ A tot /6. In the earlier literature, the multifragmentation was studied by Jakobsson et al. who measured the charge particle distribution along with their kinetic energy spectra in 16 O/ 36 Ar induced reaction between 25 and 200 MeV/nucleon representing the various phenomena in heavy ion collisions

  17. Heavy-ion irradiation induced diamond formation in carbonaceous materials

    International Nuclear Information System (INIS)

    Daulton, T. L.

    1999-01-01

    The basic mechanisms of metastable phase formation produced under highly non-equilibrium thermodynamic conditions within high-energy particle tracks are investigated. In particular, the possible formation of diamond by heavy-ion irradiation of graphite at ambient temperature is examined. This work was motivated, in part, by earlier studies which discovered nanometer-grain polycrystalline diamond aggregates of submicron-size in uranium-rich carbonaceous mineral assemblages of Precambrian age. It was proposed that the radioactive decay of uranium formed diamond in the fission particle tracks produced in the carbonaceous minerals. To test the hypothesis that nanodiamonds can form by ion irradiation, fine-grain polycrystalline graphite sheets were irradiated with 400 MeV Kr ions. The ion irradiated graphite (and unirradiated graphite control) were then subjected to acid dissolution treatments to remove the graphite and isolate any diamonds that were produced. The acid residues were then characterized by analytical and high-resolution transmission electron microscopy. The acid residues of the ion-irradiated graphite were found to contain ppm concentrations of nanodiamonds, suggesting that ion irradiation of bulk graphite at ambient temperature can produce diamond

  18. Particle induced X-ray emission

    International Nuclear Information System (INIS)

    Cohen, D.D.

    1991-08-01

    The accelerator based ion beam technique of Particle Induced X-ray Emission (PIXE) is discussed in some detail. This report pulls together all major reviews and references over the last ten years and reports on PIXE in vacuum and using external beams. The advantages, limitations, costs and types of studies that may be undertaken using an accelerator based ion beam technique such as PIXE, are also discussed. 25 refs., 7 tabs., 40 figs

  19. Pion production and particle correlations

    International Nuclear Information System (INIS)

    Kristiansson, P.

    1985-10-01

    Intermediate energy heavy ion collisions have been studied using the carbon-beam produced at the CERN SC-accelerator. Cross-sections for π + and π - have been measured over a wide range of large angles at 60, 75 and 86 MeV/nucleon. The yields and shapes are compared to a nucleon-nucleon scattering approach, which underestimates the yields by orders of magnitude. The π - /π + -ratio observed is close to unity for 12 C + 12 C, but the enhancement for 12 C + 208 Pb is much larger than expected from the neutron excess in 208 Pb. Large-angle light-particle correlations for 86 MeV/nucleon carbon induced reactions on different targets (C, Al, Cu, Au) have been studied. An excess of correlations is observed in the particle-particle scattering plane. The strength of this effect increases with observed particle mass and decreases with target mass. (author)

  20. Delivery of single accelerated particles

    International Nuclear Information System (INIS)

    McNulty, P.J.; Pease, V.P.; Bond, V.P.; Schimmerling, W.; Vosburgh, K.G.; Crebbin, K.; Everette, W.; Howard, J.

    1978-01-01

    It is desirable for certain experiments involving accelerators to have the capability of delivering just a single beam particle to the target area. The essential features of such a one-at-a-time facility are discussed. Two such facilities are described which were implemented at high-energy heavy ion accelerators without having to make major structural changes in the existing beam lines or substantially interfering with other accelerator uses. Two accelerator facilities are described which had the capability of delivering a single beam particle to the target area. This feature is necessary in certain experiments investigating visual phenomena induced by charged particles, other single particle interactions in biology, and other experiments in which the low intensities of cosmic rays need to be simulated. Both facilities were implemented without having to make structural changes in the existing beam lines or substantially interfering with other accelerator uses. (Auth.)

  1. Movement of heavy particles in tornadoes

    Science.gov (United States)

    Ingel, L. Kh.

    2017-07-01

    The horizontal movement of inertial particles in the intensive vortices, where the centrifugal force can be substantially higher than the gravity, is studied analytically. A similar problem was studied earlier for small (Stokes) particles at low Reynolds number, which allow one to be limited to the linear resistance law. It is shown that the previous results to a great extent can be extrapolated to the case of considerably heavier particles (e.g., water droplets with a diameter up to 1 mm at Reynolds numbers up to 103). The nonlinear nature of the resistance, i.e., its dependence on the particle velocity relative to the medium, should be taken into account for such particles. Some general laws are established for particle dynamics. In particular, their tangential velocity is close to the velocity of the medium, while the radial velocity is substantially lower (it is close on the order of magnitude to the geometric mean of the particle tangential velocity and the difference between the latter and the tangential velocity of the medium). The limits of applicability of the results are found, i.e., the restrictions to the size and mass/density of particles.

  2. Impact parameter dependence of the specific entropy and the light particle yield in relativistic heavy ion collisions

    International Nuclear Information System (INIS)

    Gudima, K.K.; Toneev, V.D.

    1986-01-01

    The connection between the fragment yield and the associated specific entropy of particles produced in the course of a relativistic heavy ion collision is studied within the cascade approach. The essential impact parameter dependence of the fragment yield indicates that the specific entropy increases with impact parameter and that the critical density of the system decay is the larger the more central the collision process is. The results show that the thermodynamical equilibrium limit for the entropy production is not reached for such heavy systems as Nb+Nb at 400 MeV/nucleon and that the finite size effects and the dynamical freeze-out process are dominant factors in determining the cluster yield

  3. Heavy Metals Induce Iron Deficiency Responses at Different Hierarchic and Regulatory Levels1[OPEN

    Science.gov (United States)

    2017-01-01

    In plants, the excess of several heavy metals mimics iron (Fe) deficiency-induced chlorosis, indicating a disturbance in Fe homeostasis. To examine the level at which heavy metals interfere with Fe deficiency responses, we carried out an in-depth characterization of Fe-related physiological, regulatory, and morphological responses in Arabidopsis (Arabidopsis thaliana) exposed to heavy metals. Enhanced zinc (Zn) uptake closely mimicked Fe deficiency by leading to low chlorophyll but high ferric-chelate reductase activity and coumarin release. These responses were not caused by Zn-inhibited Fe uptake via IRON-REGULATED TRANSPORTER (IRT1). Instead, Zn simulated the transcriptional response of typical Fe-regulated genes, indicating that Zn affects Fe homeostasis at the level of Fe sensing. Excess supplies of cobalt and nickel altered root traits in a different way from Fe deficiency, inducing only transient Fe deficiency responses, which were characterized by a lack of induction of the ethylene pathway. Cadmium showed a rather inconsistent influence on Fe deficiency responses at multiple levels. By contrast, manganese evoked weak Fe deficiency responses in wild-type plants but strongly exacerbated chlorosis in irt1 plants, indicating that manganese antagonized Fe mainly at the level of transport. These results show that the investigated heavy metals modulate Fe deficiency responses at different hierarchic and regulatory levels and that the interaction of metals with physiological and morphological Fe deficiency responses is uncoupled. Thus, this study not only emphasizes the importance of assessing heavy metal toxicities at multiple levels but also provides a new perspective on how Fe deficiency contributes to the toxic action of individual heavy metals. PMID:28500270

  4. Application of microbeam in bio-science and life science. Biological effects induced in bystander cells by particle microbeams

    International Nuclear Information System (INIS)

    Suzuki, Masao

    2006-01-01

    Biological events occurring in cells directly hit by radiation appear in bystander cells nearby not hit directly, which is called the bystander effect. This review describes the events and mechanisms of biological bystander effect yielded by the low-dose radiation including the microbeam. Bystander effects, particularly by charged particle beams, have been studied by two representative approaches by α-ray from plutonium (stochastic irradiation) and by particle microbeams (targeted irradiation), where a bystander effect like chromosome aberrations is shown to occur by communication between irradiated and non-irradiated cells through gap junction. Bystander effects that do not require the cell contact also occur in the irradiated cell-conditioned medium (ICCM), where, not only the short-life radicals like reactive oxygen species and NO, but also more long-life factors participate. Authors have shown the presence of such bystander-inducing factors in ICCM, producing the aberrations even 48 hr after irradiation of either low or high linear energy transfer (LET) radiation. Bystander effects can be important from the aspect of risk assessments of radiation in the terrestrial/spatial environment involving aircraft as well as in cancer therapy by low-dose heavy particle beams. (T.I)

  5. Study of the continuum in heavy ion inelastic spectra by light particle coincidence measurements

    International Nuclear Information System (INIS)

    Scarpaci, J.A.; Blumenfeld, Y.; Chomaz, P.; Frascaria, N.; Garron, J.P.; Roynette, J.C.; Suomijarvi, T.; Van der Woude, A.; Alamanos, N.; Fernandez, B.; Gillibert, A.; Van der Woude, A.; Lepine, A.

    1990-01-01

    The continuum in heavy ion inelastic spectra contains, in addition to the excitation of target nucleus states, contributions from pick-up break-up and knock out reactions. In the case of the 40 Ca + 40 Ca collision at 50 MeV/N these contributions are separated and their relative importance assessed by the measurement of light charged particles in coincidence with the inelastically scattered fragments. The pick-up break-up contribution is found to make up less than half of the cross section at high excitation energies, conversely, the knock out process is important

  6. Probability of K atomic shell ionization by heavy particles impact, in functions of the scattering angle

    International Nuclear Information System (INIS)

    Oliveira, P.M.C. de.

    1976-12-01

    A method of calculation of the K atomic shell ionization probability by heavy particles impact, in the semi-classical approximation is presented. In this approximation, the projectile has a classical trajectory. The potential energy due to the projectile is taken as perturbation of the Hamiltonian of the neutral atom. We use scaled Thomas-Fermi wave function for the atomic electrons. The method is valid for intermediate atomic number elements and particle energies of some MeV. Probabilities are calculated for the case of Ag (Z = 47) and protons of 1 and 2 MeV. Results are given as function of scattering angle, and agree well known experimental data and also improve older calculations. (Author) [pt

  7. Probiotics protect mice from CoCrMo particles-induced osteolysis

    Directory of Open Access Journals (Sweden)

    Wang Z

    2017-07-01

    Full Text Available Zhenheng Wang,* Kaiwen Xue,* Maosheng Bai, Zhantao Deng, Jingjing Gan, Gang Zhou, Hongbo Qian,* Nirong Bao, Jianning Zhao Department of Orthopaedics, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, People’s Republic of China *These authors contributed equally to this work Abstract: Wear particle-induced inflammatory osteolysis is the primary cause of aseptic loosening, which is the most common reason for total hip arthroplasty (THA failure in the med- and long term. Recent studies have suggested an important role of gut microbiota (GM in modulating the host metabolism and immune system, leading to alterations in bone mass. Probiotic bacteria administered in adequate amounts can alter the composition of GM and confer health benefits to the host. Given the inflammatory osteolysis that occurs in wear debris-induced prosthesis loosening, we examined whether the probiotic Lactobacillus casei could reduce osteolysis in a mouse calvarial resorption model. In this study, L. casei markedly protected mice from CoCrMo particles (CoPs-induced osteolysis. Osteoclast gene markers and the number of osteoclasts were significantly decreased in L. casei-treated mice. Probiotic treatment decreased the M1-like macrophage phenotype indicated by downregulation of tumor necrosis factor α (TNF-α, interleukin (IL-6 and inducible nitric oxide synthase (iNOS and increased the M2-like macrophage phenotype indicated by upregulation of IL-4, IL-10 and arginase. Collectively, these results indicated that the L. casei treatment modulated the immune status and suppressed wear particle-induced osteolysis in vivo. Thus, probiotic treatment may represent a potential preventive and therapeutic approach to reduced wear debris-induced osteolysis. Keywords: wear particles, gut microbiota, nanotoxicity, macrophage polarization, inflammatory cytokines, aseptic loosening

  8. Chemical Potentials of Quarks Extracted from Particle Transverse Momentum Distributions in Heavy Ion Collisions at RHIC Energies

    International Nuclear Information System (INIS)

    Zhao, Hong; Liu, Fu-Hu

    2014-01-01

    In the framework of a multisource thermal model, the transverse momentum distributions of charged particles produced in nucleus-nucleus (A-A) and deuteron-nucleus (d-A) collisions at relativistic heavy ion collider (RHIC) energies are investigated by a two-component revised Boltzmann distribution. The calculated results are in agreement with the PHENIX experimental data. It is found that the source temperature increases obviously with increase of the particle mass and incident energy, but it does not show an obvious change with the collision centrality. Then, the values of chemical potentials for up, down, and strange quarks can be obtained from the antiparticle to particle yield ratios in a wide transverse momentum range. The relationship between the chemical potentials of quarks and the transverse momentum with different centralities is investigated, too

  9. COMPARISON OF THE PARTICLE SIZE DISTRIBUTION OF HEAVY-DUTY DIESEL EXHAUST USING A DILUTION TAIL-PIPE SAMPLER AND IN-PLUME SAMPLER DURING ON-ROAD OPERATION

    Science.gov (United States)

    The paper compares the particle size distribution of heavy-duty diesel exhaust using a dilution tail-pipe sampler and an in-plume sampler during on-road operation. EPA's On-road Diesel Emissions Characterization Facility, modified to incorporate particle measurement instrumentat...

  10. Study of irradiation induced defects and phase instability in β phase of Zr Excel alloy with in-situ heavy ion irradiation

    International Nuclear Information System (INIS)

    Yu, H.; Yao, Z.; Kirk, M.A.; Daymond, M.R.

    2015-01-01

    In situ heavy ion irradiation with 1 MeV Kr"2"+ was carried out to study irradiation induced phase change and atomic lattice defects in theβ phase of Zr Excel alloy. No decomposition of β-Zr was observed under irradiation at either 200 "oC or 450 "oC. However, ω-Zr particles experienced shape change and shrinkage associated enrichment of Fe in the β/ω interface at 200 "oC irradiation but not at 450 "oC. The defect evolution in the β-phase was examined with single phase Zr-20Nb alloy. It was found that dislocation loops with Burgers vector 1/2 and both present in β-Zr under room temperature irradiation. (author)

  11. Heavy metal toxicity and bioavailability of dissolved nutrients to a bacterivorous flagellate are linked to suspended particle physical properties

    International Nuclear Information System (INIS)

    Boenigk, Jens; Wiedlroither, Anneliese; Pfandl, Karin

    2005-01-01

    Many dissolved substances attach easily to sediment particles. In the presence of suspended sediments bioavailability of dissolved substances is therefore, usually reduced and clays are even applied to 'wash' natural waters upon pollution. In organisms which feed on food organisms in the size range of these suspended sediment particles, however, bioavailability of such substances may even increase. For microorganisms the interaction with dissolved substances and suspended sediment particles so far has hardly been investigated. We specifically tested: (1) the importance of suspended particles as an uptake route for dissolved substances; and (2) the significance of particle surface properties, i.e. surface load and mineralogy. As a model system we used an axenically cultured strain of a widespread and often abundant flagellate ('Spumella-like' flagellate strain JBM10). We tested the toxicity of cadmium (II) and mercury (II) as well as availability of dissolved organic matter (DOM) in the absence as well as in the presence of different natural clays, i.e. a kaolinite, a montmorillonite, and a mixed clay, and of artificial silicate particles of different surface charge. When applied separately the presence of the heavy metals cadmium and mercury as well as of suspended particles negatively affected the investigated flagellate but nutritive organics supported growth of the investigated flagellate. Toxic stress response comprises behavioral changes including enhanced swimming activity and stress egestion of ingested particles and was generally similar for a variety of different flagellate species. In combination with suspended particles, the respective effect of trace metals and nutritive substances decreased. Regarding the particle quality, cadmium toxicity increased with increasingly negative surface charge, i.e. increasing surface density of silanol groups (Pearson's product moment, P = 0.005). For mercury particle mineralogy still had a significant effect (P < 0

  12. Seasonal variations of total suspended particles (TSP) and heavy metals under tropical conditions in Rio de Janeiro, Brazil

    International Nuclear Information System (INIS)

    Pfeiffer, W.C.; Trindade, H.A.; Costa-Ribeiro, C.; Londres, H.; Oliveira, A.E.

    The total suspended particle (TSP) and heavy metal concentrations are studied in Rio de Janeiro, Brazil from 1974 until 1981. The principal aims are to determine how these things vary in two different areas and how meteorological parameters responsible for the transport and dilution of atmospheric pollutants affect these areas. (M.A.C.) [pt

  13. Laser-induced breakdown spectroscopy for quantification of heavy metals in soils and sediments

    CSIR Research Space (South Africa)

    Ambushe, AA

    2010-09-01

    Full Text Available Laser-induced breakdown spectroscopy (LIBS) will be used to determine the contents of heavy metals in soils and sediments. LIBS results will be compared with the results obtained by inductively coupled plasma-optical emission spectrometry (ICP...

  14. Particle and heavy ion transport code system, PHITS, version 2.52

    International Nuclear Information System (INIS)

    Sato, Tatsuhiko; Matsuda, Norihiro; Hashimoto, Shintaro; Iwamoto, Yosuke; Noda, Shusaku; Ogawa, Tatsuhiko; Nakashima, Hiroshi; Fukahori, Tokio; Okumura, Keisuke; Kai, Tetsuya; Niita, Koji; Iwase, Hiroshi; Chiba, Satoshi; Furuta, Takuya; Sihver, Lembit

    2013-01-01

    An upgraded version of the Particle and Heavy Ion Transport code System, PHITS2.52, was developed and released to the public. The new version has been greatly improved from the previously released version, PHITS2.24, in terms of not only the code itself but also the contents of its package, such as the attached data libraries. In the new version, a higher accuracy of simulation was achieved by implementing several latest nuclear reaction models. The reliability of the simulation was improved by modifying both the algorithms for the electron-, positron-, and photon-transport simulations and the procedure for calculating the statistical uncertainties of the tally results. Estimation of the time evolution of radioactivity became feasible by incorporating the activation calculation program DCHAIN-SP into the new package. The efficiency of the simulation was also improved as a result of the implementation of shared-memory parallelization and the optimization of several time-consuming algorithms. Furthermore, a number of new user-support tools and functions that help users to intuitively and effectively perform PHITS simulations were developed and incorporated. Due to these improvements, PHITS is now a more powerful tool for particle transport simulation applicable to various research and development fields, such as nuclear technology, accelerator design, medical physics, and cosmic-ray research. (author)

  15. Heavy inertial particles in turbulent flows gain energy slowly but lose it rapidly.

    Science.gov (United States)

    Bhatnagar, Akshay; Gupta, Anupam; Mitra, Dhrubaditya; Pandit, Rahul

    2018-03-01

    We present an extensive numerical study of the time irreversibility of the dynamics of heavy inertial particles in three-dimensional, statistically homogeneous, and isotropic turbulent flows. We show that the probability density function (PDF) of the increment, W(τ), of a particle's energy over a time scale τ is non-Gaussian, and skewed toward negative values. This implies that, on average, particles gain energy over a period of time that is longer than the duration over which they lose energy. We call this slow gain and fast loss. We find that the third moment of W(τ) scales as τ^{3} for small values of τ. We show that the PDF of power-input p is negatively skewed too; we use this skewness Ir as a measure of the time irreversibility and we demonstrate that it increases sharply with the Stokes number St for small St; this increase slows down at St≃1. Furthermore, we obtain the PDFs of t^{+} and t^{-}, the times over which p has, respectively, positive or negative signs, i.e., the particle gains or loses energy. We obtain from these PDFs a direct and natural quantification of the slow gain and fast loss of the energy of the particles, because these PDFs possess exponential tails from which we infer the characteristic loss and gain times t_{loss} and t_{gain}, respectively, and we obtain t_{loss}particles is equally likely in vortical or strain-dominated regions of the flow.

  16. Italian Physical Society Search for metastable heavy charged particles with large ionisation energy loss in $pp$ collisions at $\\sqrt s = 13$ TeV using the ATLAS experiment

    CERN Document Server

    Gaudiello, A

    2017-01-01

    Many extensions of the Standard Model predict the existence of charged and heavy long-lived particles, such as R-hadrons. These particles, if produced at the Large Hadron Collider (LHC), should be non-relativistic and are therefore identifiable through the measurement of an anomalously large energy loss in the ATLAS Pixel Detector. The search for heavy long-lived particles using track information in the vicinity of the interaction vertex is sensitive for values of their lifetime in the nanosecond range. The research of metastable and stable R-hadrons with the ATLAS detector using 2015 LHC data is here reported.

  17. The heavy ion therapy project at GSI

    International Nuclear Information System (INIS)

    Kraft, G.; Becher, W.; Blasche, K.; Boehne, D.; Fischer, B.; Geissel, H.; Haberer, T.; Klabunde, J.; Kraft-Weyrather, W.; Langenbeck, G.; Muenzenberg, G.; Ritter, S.; Roesch, W.; Schardt, D.; Stelzer, H.; Schwab, T.; Gademann, G.

    1991-03-01

    The use of heavy charged particles in radiotherapy has two major advantages: Firstly, particle beams exhibit a superior dose distribution because of reduced lateral scattering, the finite range of the particles and the increased dose deposition towards the end of the particle track. Secondly, heavy ions exhibit an increased biological efficiency in the region of the increased energy deposition. This diminishes the differences in the radio response between well oxygenated and hypoxic cells as well as differences between fast and slowly proliferating cells. In addition, with high values for relative biological efficiencies, the repair capacity of cells in the tumor are selectively reduced. Both effects, the high energy deposition and the increased RBE values at the end of the particle tracks, are due to the different interaction mechanism of heavy ions with the target material and open a new field of precision and efficiency in radiotherapy. (orig.)

  18. Antitumor bystander effect induced by radiation-inducible target gene therapy combined with α particle irradiation

    International Nuclear Information System (INIS)

    Liu Hui; Jin Chufeng; Wu Yican; Ge Shenfang; Wu Lijun; FDS Team

    2012-01-01

    In this work, we investigated the bystander effect of the tumor and normal cells surrounding the target region caused by radiation-inducible target gene therapy combined with α-particle irradiation. The receptor tumor cell A549 and normal cell MRC-5 were co-cultured with the donor cells irradiated to 0.5 Gy or the non-irradiated donor cells, and their survival and apoptosis fractions were evaluated. The results showed that the combined treatment of Ad-ET and particle irradiation could induce synergistic antitumor effect on A549 tumor cell, and the survival fraction of receptor cells co-cultured with the irradiated cells decreased by 6%, compared with receptor cells co-cultured with non-irradiated cells, and the apoptosis fraction increased in the same circumstance, but no difference was observed with the normal cells. This study demonstrates that Ad-ET combined with α-particle irradiation can significantly cause the bystander effect on neighboring tumor cells by inhibiting cell growth and inducing apoptosis, without obvious toxicity to normal cells. This suggests that combining radiation-inducible TRAIL gene therapy and irradiation may improve tumor treatment efficacy by specifically targeting tumor cells and even involving the neighboring tumor cells. (authors)

  19. Defect production and subsequent effects induced by electronic energy loss of swift heavy ion

    International Nuclear Information System (INIS)

    Hou Mingdong; Liu Jie; Sun Youmei; Yin Jingmin; Yao Huijun; Duan Jinglai; Mo Dan; Zhang Ling; Chen Yanfeng; Chinese Academy of Sciences, Beijing

    2008-01-01

    Swift heavy ion in matter is one of forfront fields of nuclear physics in the world. A series of new phenomena were discovered in recent years. The history and sta- tus on the development of this field were reviewed. Electronic energy loss effects induced by swift heavy ion irradiation, such as defect production and evolution, ion latent track formation, phase transformation and anisotropy plastic deformation were introduced emphatically. A trend of future investigation was explored. (authors)

  20. Analysis of multi-fragmentation reactions induced by relativistic heavy ions using the statistical multi-fragmentation model

    Energy Technology Data Exchange (ETDEWEB)

    Ogawa, T., E-mail: ogawa.tatsuhiko@jaea.go.jp [Research Group for Radiation Protection, Division of Environment and Radiation Sciences, Nuclear Science and Engineering Directorate, Japan Atomic Energy Agency, Shirakata-Shirane, Tokai, Ibaraki 319-1195 (Japan); Sato, T.; Hashimoto, S. [Research Group for Radiation Protection, Division of Environment and Radiation Sciences, Nuclear Science and Engineering Directorate, Japan Atomic Energy Agency, Shirakata-Shirane, Tokai, Ibaraki 319-1195 (Japan); Niita, K. [Research Organization for Information Science and Technology, Shirakata-shirane, Tokai, Ibaraki 319-1188 (Japan)

    2013-09-21

    The fragmentation cross-sections of relativistic energy nucleus–nucleus collisions were analyzed using the statistical multi-fragmentation model (SMM) incorporated with the Monte-Carlo radiation transport simulation code particle and heavy ion transport code system (PHITS). Comparison with the literature data showed that PHITS-SMM reproduces fragmentation cross-sections of heavy nuclei at relativistic energies better than the original PHITS by up to two orders of magnitude. It was also found that SMM does not degrade the neutron production cross-sections in heavy ion collisions or the fragmentation cross-sections of light nuclei, for which SMM has not been benchmarked. Therefore, SMM is a robust model that can supplement conventional nucleus–nucleus reaction models, enabling more accurate prediction of fragmentation cross-sections.

  1. Analysis of multi-fragmentation reactions induced by relativistic heavy ions using the statistical multi-fragmentation model

    International Nuclear Information System (INIS)

    Ogawa, T.; Sato, T.; Hashimoto, S.; Niita, K.

    2013-01-01

    The fragmentation cross-sections of relativistic energy nucleus–nucleus collisions were analyzed using the statistical multi-fragmentation model (SMM) incorporated with the Monte-Carlo radiation transport simulation code particle and heavy ion transport code system (PHITS). Comparison with the literature data showed that PHITS-SMM reproduces fragmentation cross-sections of heavy nuclei at relativistic energies better than the original PHITS by up to two orders of magnitude. It was also found that SMM does not degrade the neutron production cross-sections in heavy ion collisions or the fragmentation cross-sections of light nuclei, for which SMM has not been benchmarked. Therefore, SMM is a robust model that can supplement conventional nucleus–nucleus reaction models, enabling more accurate prediction of fragmentation cross-sections

  2. A new setup for the investigation of swift heavy ion induced particle emission and surface modifications

    Energy Technology Data Exchange (ETDEWEB)

    Meinerzhagen, F.; Breuer, L.; Bukowska, H.; Herder, M.; Schleberger, M.; Wucher, A. [Fakultät für Physik, Universität Duisburg-Essen and Cenide, 47057 Duisburg (Germany); Bender, M.; Severin, D. [GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291 Darmstadt (Germany); Lebius, H. [CIMAP (CEA-CNRS-ENSICAEN-UCN), 14070 Caen Cedex 5 (France)

    2016-01-15

    The irradiation with fast ions with kinetic energies of >10 MeV leads to the deposition of a high amount of energy along their trajectory (up to several ten keV/nm). The energy is mainly transferred to the electronic subsystem and induces different secondary processes of excitations, which result in significant material modifications. A new setup to study these ion induced effects on surfaces will be described in this paper. The setup combines a variable irradiation chamber with different techniques of surface characterizations like scanning probe microscopy, time-of-flight secondary ion, and neutral mass spectrometry, as well as low energy electron diffraction under ultra high vacuum conditions, and is mounted at a beamline of the universal linear accelerator (UNILAC) of the GSI facility in Darmstadt, Germany. Here, samples can be irradiated with high-energy ions with a total kinetic energy up to several GeVs under different angles of incidence. Our setup enables the preparation and in situ analysis of different types of sample systems ranging from metals to insulators. Time-of-flight secondary ion mass spectrometry enables us to study the chemical composition of the surface, while scanning probe microscopy allows a detailed view into the local electrical and morphological conditions of the sample surface down to atomic scales. With the new setup, particle emission during irradiation as well as persistent modifications of the surface after irradiation can thus be studied. We present first data obtained with the new setup, including a novel measuring protocol for time-of-flight mass spectrometry with the GSI UNILAC accelerator.

  3. Radiation defects in lithium fluoride induced by heavy ions

    Energy Technology Data Exchange (ETDEWEB)

    Trautmann, C.; Schwartz, K.; Steckenreiter, T. [Gesellschaft fuer Schwerionenforschung mbH, Darmstadt (Germany); Costantini, J.M. [CEA Centre d`Etudes de Bruyeres-le-Chatel, 91 (France). DPTA/SPMC; Toulemonde, M. [Centre Interdisciplinaire de Recherches avec les Ions Lourds (CIRIL), 14 - Caen (France)

    1998-07-01

    Single crystals of lithium fluoride were irradiated with various species of heavy ions in the energy regime between 1 and 30 MeV/u. The induced radiation damage was studied with techniques such as optical absorption spectroscopy, small-angle x-ray scattering, chemical etching and profilometry, complemented by annealing experiments. Clear evidence is given for a complex track structure and defect morphology. Single defects such as F-centers are produced in a large halo of several tens of nanometers around the ion trajectory. The defect creation in this zone is similar to that under conventional radiation. For heavy ions above a critical energy loss of 10 keV/nm, new effects occur within a very small core region of 2-4 nm in diameter. The damage in this zone is responsible for chemical etching and for a characteristic anisotropic x-ray scattering. It is assumed that in this core, complex defect aggregates (e.g., cluster of color centers, molecular anions and vacancies) are created. Their formation is only slightly influenced by the irradiation temperature and takes place even at 15 K where diffusion processes of primary defects are frozen. Furthermore, irradiation with heavy ions leads to pronounced swelling effects which can be related to an intermediate zone of around 10 nm around the ion path. (orig.) 40 refs.

  4. LATTICE SIMULATIONS OF THE THERMODYNAMICS OF STRONGLY INTERACTING ELEMENTARY PARTICLES AND THE EXPLORATION OF NEW PHASES OF MATTER IN RELATIVISTIC HEAVY ION COLLISIONS

    International Nuclear Information System (INIS)

    KARSCH, F.

    2006-01-01

    At high temperatures or densities matter formed by strongly interacting elementary particles (hadronic matter) is expected to undergo a transition to a new form of matter--the quark gluon plasma--in which elementary particles (quarks and gluons) are no longer confined inside hadrons but are free to propagate in a thermal medium much larger in extent than the typical size of a hadron. The transition to this new form of matter as well as properties of the plasma phase are studied in large scale numerical calculations based on the theory of strong interactions--Quantum Chromo Dynamics (QCD). Experimentally properties of hot and dense elementary particle matter are studied in relativistic heavy ion collisions such as those currently performed at the relativistic heavy ion collider (RHIC) at BNL. We review here recent results from studies of thermodynamic properties of strongly interacting elementary particle matter performed on Teraflops-Computer. We present results on the QCD equation of state and discuss the status of studies of the phase diagram at non-vanishing baryon number density

  5. Reaction mechanism and spectroscopy of transfer reactions induced by heavy ions

    International Nuclear Information System (INIS)

    Lemaire, M.-C.

    1977-01-01

    The specific features displayed by data on heavy ion elastic and inelastic angular distributions are discussed, and their physical origin is pointed out from semi-classical calculations in counterpart ambiguities in the phenomenological description of the optical potential appear. Two nucleon transfer reactions induced by heavy ions successfully point out important contributions of a two-step process where the transfer is proceeding via target and residual nucleus inelastic excitation. At incident energies not too high above the Coulomb barrier, such process produces clear shape changes between different final state angular distributions. At higher incident energy, the angular distributions are forward peaked and display oscillations for both mechanisms. As for four-nucleon transfer reactions, the existing data suggest that the nucleons are well transferred into a Os relative

  6. Correction of Doppler broadening of {gamma}-ray lines induced by particle emission in heavy-ion induced fusion-evaporation reactions

    Energy Technology Data Exchange (ETDEWEB)

    Nyberg, J; Seweryniak, D; Fahlander, C; Insua-Cao, P [Uppsala Univ. (Sweden). Dept. of Radiation Sciences; Johnson, A; Cederwall, B [Manne Siegbahn Inst. of Physics, Stockholm (Sweden); [Royal Inst. of Tech., Stockholm (Sweden); Adamides, E; Piiparinen, M [National Centre for Scientific Research, Ag. Paraskevi, Attiki (Greece); Atac, A; Norlin, L O [Niels Bohr Inst., Copenhagen (Denmark); Ideguchi, E; Mitarai, S [Kyushu Univ., Fukuoka (Japan). Dept. of Physics; Julin, R; Juutinen, S; Tormanen, S; Virtanen, A [Jyvaeskylae Univ. (Finland). Dept. of Physics; Karczmarczyk, W; Kownacki, J [Warsaw Univ. (Poland); Schubart, R [Hahn-Meitner-Institut Berlin GmbH (Germany)

    1992-08-01

    The effect of particle emission on the peak shape of {gamma}-ray lines have been investigated using the NORDBALL detector system. By detecting neutrons, protons and {alpha} particles emitted in the {sup 32}S (95 MeV) + {sup 27}Al reaction, the energy and direction of emission of the residual nuclei could be determined and subsequently used for an event-by -event Doppler correction of the detected {gamma} rays. Extensive Monte Carlo simulations were performed to study how the different Doppler phenomena influence the peak shape and in particular which particle detector properties are important for the Doppler correction. (author). 2 refs., 1 tab., 4 figs.

  7. Effect of heavy ion irradiation on thermodynamically equilibrium Zr-Excel alloy

    Science.gov (United States)

    Yu, Hongbing; Liang, Jianlie; Yao, Zhongwen; Kirk, Mark A.; Daymond, Mark R.

    2017-05-01

    The thermodynamically equilibrium state was achieved in a Zr-Sn-Nb-Mo alloy by long-term annealing at an intermediate temperature. The fcc intermetallic Zr(Mo, Nb)2 enriched with Fe was observed at the equilibrium state. In-situ 1 MeV Kr2+ heavy ion irradiation was performed in a TEM to study the stability of the intermetallic particles under irradiation and the effects of the intermetallic particle on the evolution of type dislocation loops at different temperatures from 80 to 550 °C. Chemi-STEM elemental maps were made at the same particles before and after irradiation up to 10 dpa. It was found that no elemental redistribution occurs at 200 °C and below. Selective depletion of Fe was observed from some precipitates under irradiation at higher temperatures. No change in the morphology of particles and no evidence showing a crystalline to amorphous transformation were observed at all irradiation temperatures. The formation of type dislocation loops was observed under irradiation at 80 and 200 °C, but not at 450 and 550 °C. The loops were non-uniformly distributed; a localized high density of type dislocation loops were observed near the second phase particles; we suggest that loop nucleation is favored as a result of the stress induced by the particles, rather than by elemental redistribution. The stability of the second phase particles and the formation of the type loops under heavy ion irradiation are discussed.

  8. Method of determining the partial cross sections in a heavy liquid. Application to the production of strange particles by high energy π"-

    International Nuclear Information System (INIS)

    Lloret, Antonio

    1964-01-01

    This research thesis reports the study if the measurement of cross sections on proton, and more particularly the development of a method of determination of cross sections which takes problems raised by a heavy liquid into account. This method is applied with sufficiently high energies for the Fermi momentum to have no influence on cross sections. The author first presents the general method of determination of partial cross sections in a heavy liquid: case of a hydrogen chamber, ideal case of a heavy liquid chamber without possibility of secondary interactions nor evaporations, search for a formula removing secondary interactions, correction due to the fact that the number of neutrons is not equal to the number of protons in the mixture nuclei, application to cross sections of production of high energy strange particles, calculation of the number of produced high energy particles. The experiment is then presented with its chamber, its measurement and calculation techniques. The author then reports and discusses cross section calculations and compares results with those of previous experiments. The last part addresses the study of secondary interactions in nuclei

  9. Applications of particle induced X-ray emission

    International Nuclear Information System (INIS)

    Akselsson, K. R.

    1978-01-01

    In Particle Induced X-ray Emission (PIXE) analysis samples are bombarded by protons or α-particles of a few MeV/u. The induced characteristic x-rays are detected with a x-ray detector e.g. a Si(Li)-detector. The energies of the x-ray peaks are characteristic for the elements in the samples and the intensities of the x-ray transitions are proportional to the abundances of the elements. The research area which first attracted those of us working with PIXE was the study of sources, transport and deposition of airborne particulates. Sources, transport, wet deposition, other applications where PIXE is already known to be competitive are trace elemental analysis of water below the ppb-level and analyses requiring a space resolution of 1-10μ. However, there is still much to do for physicists in developing the full potential of low-energy accelerators as analytical tools in multidisciplinary teams. (JIW)

  10. Hartree--Slater calculation of the cross section for L-shell ionization of argon by simple heavy charged particles

    International Nuclear Information System (INIS)

    Choi, B.

    1975-01-01

    The cross sections for L-shell and subshell ionization by direct Coulomb excitation of argon by incident heavy charged particles are evaluated. Incident particles are described in the plane-wave Born approximation, and nonrelativistic Hartree-Slater (HS) wave functions are used for the atomic electrons. Form factors, energy distributions, and ionization cross sections are compared with those obtained from screened hydrogenic wave functions. At most incident energies, the HS results for the total ionization cross section are only slightly smaller than those obtained with screened hydrogenic wave functions, but considerable discrepancies are found for form factors and energy distributions near the ionization threshold

  11. Introduction of chromosome aberrations in mammalian cells after heavy ion exposure

    International Nuclear Information System (INIS)

    Ritter, S.; Kraft-Weyrather, W.; Scholz, M.; Kraft, G.

    1991-01-01

    The induction of chromosome aberrations by heavy charged particles was studied in V79 Chinese hamster cells over a wide range of energies (3-100 MeV/u) and LET (20-16000 keV/μm). For comparison, X-ray experiments were performed. Our data indicate quantitative and qualitative differences in the response of cells to particle and x-ray irradiation. For the same level of cell survival the amount of damaged cells which can be observed is smaller in heavy ion (11.4 MeV/u Ar) irradiated samples. The highest yield of damaged cells is found 8 to 12 hours after particle irradiation and 4 hours after x-irradiation. Differences in the amounts of damaged cells are attributed to cell cycle perturbations which interfere with the expression of damage. After heavy ion exposure the amount of cells reaching mitosis (mitotic index) decreases drastically and not all damaged cells reach mitosis with 48 hours after exposure. A portion of cells die in interphase. Cell cycle delays induced by x-ray irradiation are less pronounced and all cells reach the first post-irradiation mitosis within 24 hours after irradiation. Additionally, the damage produced by charged particles seems to be more severe. The disintegration of chromosomes was only observed after high LET radiation; an indication of the high and local energy deposition in the particle track. Only cross sections for the induction of chromosome aberrations in mitotic cells were reported in this paper because of the problems arising from the drastic cell cycle perturbations. In this case, cells were irradiated in mitosis and assayed immediately. (orig.)

  12. Effects of heavy-ion radiation on the brain vascular system

    International Nuclear Information System (INIS)

    Yang, T.C.; Craise, L.M.; Tobias, C.A.

    1985-01-01

    In the laboratory, the authors have been studying the effects of heavy-ion radiation on the vascular system, using neonatal rats as a model system. They investigated the response of the brain vascular system to ionizing radiation and found that distinct petechial hemorrhages developed in the cerebral cortex within a few hours after irradiation, reached a maximum after about 13 to 24 hours, and then decreased exponentially with time. No brain hemorrhage was found in neonatal rats 12 days after irradiation. Heavy ions induce more hemorrhages than x rays for a given dose, and the RBE for 670-MeV/u neon particles ranges from about 2.0 for low doses to about 1.4 for high doses

  13. Corrections to the rho-parameter due to a heavy Higgs particle

    International Nuclear Information System (INIS)

    Bij, J.J. van der.

    1983-01-01

    The main part of this thesis is concerned with the calculation of the two-loop contribution to the rho-parameter, i.e. the ratio of charged and neutral vector boson masses, due to a heavy Higgs particle. It involves the calculation of a large number of Feynman diagrams. The result is that a contribution growing like m 2 exists (m = Higgs mass), but it does not correspond to the poles at n=3 in the non-linear model. First the model is introduced, the precise definition of rho is given and the formal connection with the non-linear model is derived. Then the one-loop infinities are calculated. It is shown that no m 2 corrections are observable in one loop and the log m 2 correction to rho is calculated. Finally the two-loop correction to rho is calculated. (Auth.)

  14. Particles from wood smoke and traffic induce differential pro-inflammatory response patterns in co-cultures

    International Nuclear Information System (INIS)

    Kocbach, Anette; Herseth, Jan Inge; Lag, Marit; Refsnes, Magne; Schwarze, Per E.

    2008-01-01

    The inflammatory potential of particles from wood smoke and traffic has not been well elucidated. In this study, a contact co-culture of monocytes and pneumocytes was exposed to 10-40 μg/cm 2 of particles from wood smoke and traffic for 12, 40 and 64 h to determine their influence on pro-inflammatory cytokine release (TNF-α, IL-1, IL-6, IL-8) and viability. To investigate the role of organic constituents in cytokine release the response to particles, their organic extracts and the washed particles were compared. Antagonists were used to investigate source-dependent differences in intercellular signalling (TNF-α, IL-1). The cytotoxicity was low after exposure to particles from both sources. However, wood smoke, and to a lesser degree traffic-derived particles, induced a reduction in cell number, which was associated with the organic fraction. The release of pro-inflammatory cytokines was similar for both sources after 12 h, but traffic induced a greater release than wood smoke particles with increasing exposure time. The organic fraction accounted for the majority of the cytokine release induced by wood smoke, whereas the washed traffic particles induced a stronger response than the corresponding organic extract. TNF-α and IL-1 antagonists reduced the release of IL-8 induced by particles from both sources. In contrast, the IL-6 release was only reduced by the IL-1 antagonist during exposure to traffic-derived particles. In summary, particles from wood smoke and traffic induced differential pro-inflammatory response patterns with respect to cytokine release and cell number. Moreover, the influence of the organic particle fraction and intercellular signalling on the pro-inflammatory response seemed to be source-dependent

  15. Techniques for the research on mass deposition effects in the bio-materials induced by heavy ion implantation

    International Nuclear Information System (INIS)

    Yuan Shibin; Wei Zengquan; Li Qiang

    2002-01-01

    Researchers have used heavy ion beams to implant small biomolecules, followed by advanced instrumental analysis to make preliminary studies on mass deposition induced by ion implantation. But research reports on the biological effects, i.e. mass deposition effects induced by mass deposition in living tissues, cells and macro-biomolecules have not been delivered hitherto. In the near future radioactive heavy ion beams will be possible to implant living cells and biomolecules, and auto-radiography, radioactive measurements and molecular biological techniques will be employed to further studies on the effects

  16. Study of Particle Production and Nuclear Fragmentation in Relativistic Heavy-Ion Collisions in Nuclear Emulsions

    CERN Multimedia

    2002-01-01

    % EMU11 \\\\ \\\\ We propose to use nuclear emulsions for the study of nuclear collisions of $^{207}$Pb, $^{197}$Au, and any other heavy-ion beams when they are available. We have, in the past, used $^{32}$S at 200A~GeV and $^{16}$O at 200A and 60A~GeV from CERN (Experiment EMU08) and at present the analysis is going on with $^{28}$Si beam from BNL at 14.5A~GeV. It will be important to compare the previous and the present investigations with the new $^{207}$Pb beam at 60-160A~GeV. We want to measure in nuclear emulsion, on an event by event basis, shower particle multiplicity, pseudorapidity density and density fluctuations of charged particles, charge multiplicity and angular distributions of projectile fragments, production and interaction cross-sections of heavily ionizing particles emitted from the target fragmentation. Special emphasis will be placed on the analysis of events produced in the central collisions which are selected on the basis of low energy fragments emitted from the target excitation. It woul...

  17. Antioxidant effect of vitamin E treatment on some heavy metals-induced renal and testicular injuries in male mice

    OpenAIRE

    Al-Attar, Atef M.

    2010-01-01

    Toxic heavy metals in water, air and soil are global problems that are a growing threat to humanity. Heavy metals are widely distributed in the environment and some of them occur in food, water, air and tissues even in the absence of occupational exposure. The antioxidant and protective influences of vitamin E on a mixture of some heavy metals (Pb, Hg, Cd and Cu)-induced oxidative stress and renal and testicular injuries were evaluated in male mice. Exposure of mice to these heavy metals in d...

  18. Detection of Genetic Variations in Marine Algae Ulva lactuca (Chlorophyta Induced by Heavy Metal Pollutants

    Directory of Open Access Journals (Sweden)

    Basel Saleh

    2015-09-01

    Full Text Available Ulva lactuca (Chlorophyta green macroalgae has been successfully used as bioindicator for heavy metals pollution in ecosystems. Random amplified microsatellite polymorphism (RAMP marker was employed to investigate genetic DNA pattern variability in green U. lactuca 5 days after exposure to Cu, Pb, Cd and Zn heavy metals stress. Genomic template stability (GTS% value was employed as a qualitative DNA changes measurement based on RAMP technique. In this respect, estimated GTS% value was recorded to be 65.215, 64.630, 59.835 and 59.250% for Pb, Cu, Cd and Zn treatment, respectively. Moreover, genetic similarity (GS induced by the above heavy metals was also evaluated to measure genetic distance between algae treated plants and their respective control. In this respect, estimated GS values generated by RAMP marker ranged between 0.576 (between control and Zn treatment - 0.969 (for both case; between Pb and Cu and between Cd and Zn treatment with an average of 0.842. Based upon data presented herein based on variant bands number (VB, GTS% and GS values; the present study could be suggested that Pb and Cu followed similar tendency at genomic DNA changes. Similar finding was also observed with Cd and Zn ions. Thereby, RAMP marker successfully highlighted DNA change patterns induced by heavy metals stress.

  19. Preparing poly (caprolactone) micro-particles through solvent-induced phase separation

    DEFF Research Database (Denmark)

    Li, Xiaoqiang; Kanjwal, Muzafar Ahmed; Stephansen, Karen

    2012-01-01

    Poly (caprolactone) (PCL) particles with the size distribution from 1 to 100 μm were prepared through solvent-induced phase separation, in which polyvinyl-alcohol (PVA) was used as the matrix-forming polymer to stabilize PCL particles. The cloud point data of PCL-acetone-water was determined...

  20. Heavy particle detection characteristics of an MWPC operating at low (1 <= p <= 30 mbar) gas pressures

    International Nuclear Information System (INIS)

    Moeller, G.; Presser, G.; Staehler, J.

    1981-01-01

    Pulse heights, timing properties and detection efficiencies of an MWPC were measured with 5.5 MeV alpha particles for different counting gases at low pressures. The pulse heights show a striking nonmonotonic dependence on the gas pressure that can be explained by a simple model of the amplification process at high reduced electric fields. The consequences of the observed pressure dependence of pulse heights for the detection of heavy ions with low pressure MWPCs are discussed. (orig.)

  1. Implications of a high-mass diphoton resonance for heavy quark searches

    Energy Technology Data Exchange (ETDEWEB)

    Banerjee, Shankha; Barducci, Daniele; Bélanger, Geneviève; Delaunay, Cédric [LAPTh, Université Savoie Mont Blanc, CNRS B.P. 110,F-74941 Annecy-le-Vieux (France)

    2016-11-25

    Heavy vector-like quarks coupled to a scalar S will induce a coupling of this scalar to gluons and possibly (if electrically charged) photons. The decay of the heavy quark into Sq, with q being a Standard Model quark, provides, if kinematically allowed, new channels for heavy quark searches. Inspired by naturalness considerations, we consider the case of a vector-like partner of the top quark. For illustration, we show that a singlet partner can be searched for at the 13 TeV LHC through its decay into a scalar resonance in the 2γ+ℓ+X final states, especially if the diphoton branching ratio of the scalar S is further enhanced by the contribution of non coloured particles. We then show that conventional heavy quark searches are also sensitive to this new decay mode, when S decays hadronically, by slightly tightening the current selection cuts. Finally, we comment about the possibility of disentangling, by scrutinising appropriate kinematic distributions, heavy quark decays to St from other standard decay modes.

  2. Preequilibrium particle emissions and in-medium effects on the pion production in heavy-ion collisions

    Energy Technology Data Exchange (ETDEWEB)

    Feng, Zhao-Qing [Chinese Academy of Sciences, Institute of Modern Physics, Lanzhou (China)

    2017-02-15

    Within the framework of the Lanzhou quantum molecular dynamics (LQMD) transport model, pion dynamics in heavy-ion collisions near threshold energies and the emission of preequilibrium particles (nucleons and light complex fragments) have been investigated. A density, momentum and isospin-dependent pion-nucleon potential based on the Δ-hole model is implemented in the transport approach, which slightly leads to the increase of the π{sup -}/π{sup +} ratio, but reduces the total pion yields. It is found that a bump structure of the π{sup -}/π{sup +} ratio in the kinetic energy spectra appears at the pion energy close to the Δ(1232) resonance region. The yield ratios of neutrons to protons from the squeeze-out particles perpendicular to the reaction plane are sensitive to the stiffness of nuclear symmetry energy, in particular at the high-momentum (kinetic energy) tails. (orig.)

  3. Pre-scission particle and gamma-ray emission in heavy-ion induced fission

    International Nuclear Information System (INIS)

    Newton, J.O.

    1989-02-01

    An introduction is given to the physics of the equilibrium transition model and of dissipative nuclear dynamics. Experimental data on pre-scission particle and gamma-ray emission and their interpretation are reviewed. They appear to indicate overdamped motion of the nuclear fluid. A time scale for compound-nucleus fission of about 30x10 -21 sec or greater is indicated, whilst that for quasi- or fast-fission is somewhat shorter. 99 refs., 28 figs

  4. Heavy-Ion Collimation at the Large Hadron Collider Simulations and Measurements

    CERN Document Server

    AUTHOR|(CDS)2083002; Wessels, Johannes Peter; Bruce, Roderik; Wessels, Johannes Peter; Bruce, Roderik

    The CERN Large Hadron Collider (LHC) stores and collides proton and $^{208}$Pb$^{82+}$ beams of unprecedented energy and intensity. Thousands of superconducting magnets, operated at 1.9 K, guide the very intense and energetic particle beams, which have a large potential for destruction. This implies the demand for a multi-stage collimation system to provide protection from beam-induced quenches or even hardware damage. In heavy-ion operation, ion fragments with significant rigidity offsets can still scatter out of the collimation system. When they irradiate the superconducting LHC magnets, the latter risk to quench (lose their superconducting property). These secondary collimation losses can potentially impose a limitation for the stored heavy-ion beam energy. Therefore, their distribution in the LHC needs to be understood by sophisticated simulations. Such simulation tools must accurately simulate the particle motion of many different nuclides in the magnetic LHC lattice and simulate their interaction with t...

  5. Observation of an Energy-Dependent Difference in Elliptic Flow between Particles and Antiparticles in Relativistic Heavy Ion Collisions

    Czech Academy of Sciences Publication Activity Database

    Adamczyk, L.; Adkins, J. K.; Agakishiev, G.; Aggarwal, M. M.; Ahammed, Z.; Alekseev, I.; Alford, J.; Anson, C.; Barnovská, Zuzana; Bielčík, J.; Bielčíková, Jana; Chaloupka, P.; Chung, Paul; Hajková, O.; Kapitán, Jan; Pachr, M.; Rusňák, Jan; Šumbera, Michal; Tlustý, David

    2013-01-01

    Roč. 110, č. 14 (2013), s. 142301 ISSN 0031-9007 R&D Projects: GA ČR GA13-20841S Institutional support: RVO:61389005 Keywords : STAR * elliptic flow * heavy ion collisions * particles and antiparticles comparations Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders Impact factor: 7.728, year: 2013 http://prl. aps .org/pdf/PRL/v110/i14/e142301

  6. Elastohydrodynamic lubrication in point contact on the surfaces of particle-reinforced composite

    Science.gov (United States)

    Chen, Keying; Zeng, Liangcai; Wu, Zhenpeng; Zheng, Feilong

    2018-04-01

    Appreciable friction and serious wear are common challenges in the operation of advanced manufacturing equipment, and friction pairs may be susceptible to damage even with oil lubrication when point contact exists. In this study, a type of particle-reinforced composite material is introduced for one of the components of a heavy-load contact pair, and the performance improvement of elastohydrodynamic lubrication (EHL) is analyzed considering the rheological properties of non-Newtonian fluids. The Ree-Eyring EHL model is used considering the surface of the particle-reinforced composite, in which the film thickness includes the particle-induced elastic deformation. The problem of inclusions with different eigenstrains is solved by using Galerkin vectors. The influences of particle properties, size, burial depth, and interparticle distance on point-contact EHL are investigated. Furthermore, using several cases, the structural parameters of the particles in the composites are optimized, and an appropriate parameter range is obtained with the goal of reducing friction. Finally, the results for the EHL traction coefficient demonstrate that appropriate particle properties, size, burial depth, and interparticle distance can effectively reduce the traction coefficient in heavy-load contact.

  7. [Studies of heavy-ion induced reactions]: Annual progress report

    International Nuclear Information System (INIS)

    Mignerey, A.C.

    1986-10-01

    An experiment was performed at the Lawrence Berkeley Laboratory Bevalac, extending previous studies using inverse reactions to 50 MeV/u 139 La incident on targets of C and Al. Studies of excitation energy division in lower energy division in lower energy heavy-ion reactions were furthered using kinematic coincidences to measure the excitation energies of primary products in the Fe + Ho reaction at 12 MeV/u. These results will provide important systematics for comparisons with previous measurements at 9 MeV/u on the same system and at 15 MeV/u on the Fe + Fe and Fe + U systems. Also studied were different aspects of 15 MeV/u Fe-induced reactions, with experiments performed at the Oak Ridge HHIRF. The first three contributions of this report constitute a major portion of the results from this research. Finally, at the Lawrence Berkeley Laboratory Bevalac a large detector array for coincident detection of fragmentation products in heavy-ion collisions below 100 MeV/u is being built. A list of publications, personnel, and activities is provided

  8. Rare particles

    International Nuclear Information System (INIS)

    Kutschera, W.

    1984-01-01

    The use of Accelerator Mass Spectrometry (AMS) to search for hypothetical particles and known particles of rare processes is discussed. The hypothetical particles considered include fractionally charged particles, anomalously heavy isotopes, and superheavy elements. The known particles produced in rare processes discussed include doubly-charged negative ions, counting neutrino-produced atoms in detectors for solar neutrino detection, and the spontaneous emission of 14 C from 223 Ra. 35 references

  9. Study of irradiation induced defects and phase instability in β phase of Zr Excel alloy with in-situ heavy ion irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Yu, H.; Yao, Z., E-mail: 12hy1@queensu.ca [Queen' s University, Department of Mechanical and Materials Engineering, Kingston, ON (Canada); Kirk, M.A. [Argonne National Laboratory, Materials Science Division, Argonne, IL (United States); Daymond, M.R. [Queen' s University, Department of Mechanical and Materials Engineering, Kingston, ON (Canada)

    2015-07-01

    In situ heavy ion irradiation with 1 MeV Kr{sup 2+} was carried out to study irradiation induced phase change and atomic lattice defects in theβ phase of Zr Excel alloy. No decomposition of β-Zr was observed under irradiation at either 200 {sup o}C or 450 {sup o}C. However, ω-Zr particles experienced shape change and shrinkage associated enrichment of Fe in the β/ω interface at 200 {sup o}C irradiation but not at 450 {sup o}C. The defect evolution in the β-phase was examined with single phase Zr-20Nb alloy. It was found that dislocation loops with Burgers vector 1/2<111> and <001> both present in β-Zr under room temperature irradiation. (author)

  10. Subway particles are more genotoxic than street particles and induce oxidative stress in cultured human lung cells.

    Science.gov (United States)

    Karlsson, Hanna L; Nilsson, Lennart; Möller, Lennart

    2005-01-01

    Epidemiological studies have shown an association between airborne particles and a wide range of adverse health effects. The mechanisms behind these effects include oxidative stress and inflammation. Even though traffic gives rise to high levels of particles in the urban air, people are exposed to even higher levels in the subway. However, there is a lack of knowledge regarding how particles from different urban subenvironments differ in toxicity. The main aim of the present study was to compare the ability of particles from a subway station and a nearby very busy urban street, respectively, to damage DNA and to induce oxidative stress. Cultured human lung cells (A549) were exposed to particles, DNA damage was analyzed using single cell gel electrophoresis (the comet assay), and the ability to induce oxidative stress was measured as 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) formation in lung cell DNA. We found that the subway particles were approximately eight times more genotoxic and four times more likely to cause oxidative stress in the lung cells. When the particles, water extracts from the particles, or particles treated with the metal chelator deferoxamine mesylate were incubated with 2'-deoxyguanosine (dG) and 8-oxodG was analyzed, we found that the oxidative capacity of the subway particles was due to redox active solid metals. Furthermore, analysis of the atomic composition showed that the subway particles to a dominating degree (atomic %) consisted of iron, mainly in the form of magnetite (Fe3O4). By using electron microscopy, the interaction between the particles and the lung cells was shown. The in vitro reactivity of the subway particles in combination with the high particle levels in subway systems give cause of concern due to the high number of people that are exposed to subway particles on a daily basis. To what extent the subway particles cause health effects in humans needs to be further evaluated.

  11. Composition of heavy ions in solar energetic particle events

    International Nuclear Information System (INIS)

    Fan, C.Y.; Gloeckler, G.

    1983-01-01

    The elemental, charge state, and isotopic composition of approximately 1 to 20 MeV per nucleon ions in solar energetic particle (SEP) events was determined and current understanding of the nature of solar and interplanetary processes which may explain the observations are outlined. The composition within individual SEP events may vary both with time and energy, and will in general be different from that in other SEP events. Average values of relative abundances measured in a large number of SEP events, however are found to be roughly energy independent in the approximately 1 to approximately 20 MeV per nucleon range, and show a systematic deviation from photospheric abundances which seem to be organized in terms of the first ionization potential of the ion. Direct measurements of the charge states of SEPs have revealed the surprisingly common presence of energetic He(+) along with heavy ions with typical coronal ionization states. High resolution measurements of isotopic abundance ratios in a small number of SEP events show these to be consistent with the universal composition except for the puzzling overabundance of the SEP Ne-22 relative to this isotopes ratio in the solar wind

  12. NLO corrections to production of heavy particles at hadron colliders

    International Nuclear Information System (INIS)

    Pagani, Davide

    2013-01-01

    In this thesis we study specific aspects of the production of heavy particles at hadron colliders, with emphasis on precision predictions including next-to-leading order (NLO) corrections from the strong and electroweak interactions. In the first part of the thesis we consider the top quark charge asymmetry. In particular, we discuss in detail the calculation of the electroweak contributions from the asymmetric part of the top quark pair production cross section at O(α 2 s α) and O(α 2 ) and their numerical impact on predictions for the asymmetry measurements at the Tevatron. These electroweak contributions provide a non-negligible addition to the QCD-induced asymmetry with the same overall sign and, in general, enlarge the Standard Model predictions by a factor around 1.2, diminishing the deviations from experimental measurements. In the second part of the thesis we consider the production of squarks, the supersymmetric partners of quarks, at the Large Hadron Collider (LHC). We discuss the calculation of the contribution of factorizable NLO QCD corrections to the production of squark-squark pairs combined at fully differential level with squark decays. Combining the production process with two different configurations for the squark decays, our calculation is used to provide precise phenomenological predictions for two different experimental signatures that are important for the search of supersymmetry at the LHC. We focus, for one signature, on the impact of our results on important physical differential distributions and on cut-and-count searches performed by the ATLAS and CMS collaborations. Considering the other signature, we analyze the effects from NLO QCD corrections and from the combination of production and decays on distributions relevant for parameter determination. In general, factorizable NLO QCD corrections have to be taken into account to obtain precise phenomenological predictions for the analyzed distributions and inclusive quantities. Moreover

  13. [Relativistic heavy ion research

    International Nuclear Information System (INIS)

    1990-01-01

    At Brookhaven National Laboratory, participation in the E802 Experiment, which is the first major heavy-ion experiment at the BNL-AGS, was the main focus of the group during the past four years. The emphases of the E802 experiment were on (a) accurate particle identification and measurements of spectra over a wide kinematical domain (5 degree LAB < 55 degree, p < 20 GeV/c); and (b) measurements of small-angle two-particle correlations, with event characterization tools: multiplicity array, forward and large-angle calorimeters. This experiment and other heavy ion collision experiments are discussed in this report

  14. Simulation of diffusion-induced stress using reconstructed electrodes particle structures generated by micro/nano-CT

    International Nuclear Information System (INIS)

    Lim, Cheolwoong; Yan Bo; Yin Leilei; Zhu Likun

    2012-01-01

    Highlights: ► The microstructure of LIB electrodes was obtained by X-ray micro/nano-CT. ► We studied diffusion-induced stresses based on realistic 3D microstructures. ► Stresses depend on geometric characteristics of electrode particle. ► Stresses in a real particle are much higher than those in a spherical particle. - Abstract: Lithium ion batteries experience diffusion-induced stresses during charge and discharge processes which can cause electrode failure in the form of fracture. Previous diffusion-induced stress models and simulations are mainly based on simple active material particle structures, such as spheres and ellipsoids. However, the simple structure model cannot reveal the stress development in a real complex lithium ion battery electrode. In this paper, we studied the diffusion-induced stresses numerically based on a realistic morphology of reconstructed particles during the lithium ion intercalation process. The morphology of negative and positive active materials of a lithium ion battery was determined using X-ray micro/nano computed tomography technology. Diffusion-induced stresses were simulated at different C rates under galvonostatic conditions and compared with spherical particles. The simulation results show that the intercalation stresses of particles depend on their geometric characteristics. The highest von Mises stress and Tresca stress in a real particle are several times higher than the stresses in a spherical particle with the same volume.

  15. Mesh Refinement for Particle-In-Cell Plasma Simulations: Applications to - and benefits for - Heavy-Ion-Fusion

    International Nuclear Information System (INIS)

    Vay, J.-L.; Colella, P.; McCorquodale, P.; Van Straalen, B.; Friedman, A.; Grote, D.P.

    2002-01-01

    The numerical simulation of the driving beams in a heavy ion fusion power plant is a challenging task, and simulation of the power plant as a whole, or even of the driver, is not yet possible. Despite the rapid progress in computer power, past and anticipated, one must consider the use of the most advanced numerical techniques, if we are to reach our goal expeditiously. One of the difficulties of these simulations resides in the disparity of scales, in time and in space, which must be resolved. When these disparities are in distinctive zones of the simulation region, a method which has proven to be effective in other areas (e.g., fluid dynamics simulations) is the mesh refinement technique. They discuss the challenges posed by the implementation of this technique into plasma simulations (due to the presence of particles and electromagnetic waves). They will present the prospects for and projected benefits of its application to heavy ion fusion. In particular to the simulation of the ion source and the final beam propagation in the chamber. A collaboration project is under way at LBNL between the Applied Numerical Algorithms Group (ANAG) and the HIF group to couple the Adaptive Mesh Refinement (AMR) library (CHOMBO) developed by the ANAG group to the Particle-In-Cell accelerator code WARP developed by the HIF-VNL. They describe their progress and present their initial findings

  16. Monte Carlo simulation of fast electrons and heavy particles in the CDS of nitrogen dc glow discharge

    International Nuclear Information System (INIS)

    Yu, W.; Zhang, L.Z.; Wang, J.L.; Han, L.; Fu, G.S.

    2001-01-01

    The characteristics of fast electrons (e - ) and heavy particles (N 2 + , N + , N 2f , N f ) in the cathode dark space (CDS) of nitrogen dc glow discharge are simultaneously studied by Monte Carlo simulation. The calculated energy and angular distributions of these particles at different positions from the cathode provide a clear picture of their transport behaviours within the CDS. The density and mean energy of these particles indicate that the electrons and the atomic ions (N + ) are the main high-energy species and the molecular ions (N 2 + ) are the major ions in the CDS. It can be seen from the energy distributions of the bombarding particles at the cathode surface that the molecular ions and the fast atoms (N f ) are the main active species participating in the cathode nitride material synthesis process. The influence of the backscattering of the electrons from the negative glow to the CDS is also investigated. All the calculated results provide good information on the spatial characteristics of the particles considered in this paper and also their internal connections in the CDS of nitrogen dc glow discharge. (author)

  17. Vortex-Breakdown-Induced Particle Capture in Branching Junctions.

    Science.gov (United States)

    Ault, Jesse T; Fani, Andrea; Chen, Kevin K; Shin, Sangwoo; Gallaire, François; Stone, Howard A

    2016-08-19

    We show experimentally that a flow-induced, Reynolds number-dependent particle-capture mechanism in branching junctions can be enhanced or eliminated by varying the junction angle. In addition, numerical simulations are used to show that the features responsible for this capture have the signatures of classical vortex breakdown, including an approach flow aligned with the vortex axis and a pocket of subcriticality. We show how these recirculation regions originate and evolve and suggest a physical mechanism for their formation. Furthermore, comparing experiments and numerical simulations, the presence of vortex breakdown is found to be an excellent predictor of particle capture. These results inform the design of systems in which suspended particle accumulation can be eliminated or maximized.

  18. Trends of light particle spectra observed in nucleus-nucleus collisions

    International Nuclear Information System (INIS)

    Awes, T.C.; Poggi, G.; Saini, S.; Gelbke, C.K.; Legrain, R.; Westfall, G.D.

    1981-01-01

    The emission of energetic light particles (p,d,t) has been studied for 16 O induced reactions on Al, Zr and Au targets at the incident energies of 140, 215 and 310 MeV. The light-particle energy spectra have been analyzed in terms of a moving thermal source. The apparent temperatures exhibit a systematic variation as a function of the incident energy per nucleon above the Coulomb barrier. The observed trend can be extrapolated in a smooth fashion to temperatures obtained in relativistic heavy-ion collisions. (orig.)

  19. Proceedings of the 12. International Symposium on Nuclear Physics - Heavy-Ion Collisions and Nuclear Fission - organized by the Technical University of Dresden, November 22-26, 1982 in Gaussig (GDR)

    International Nuclear Information System (INIS)

    Reif, R.; Teichert, J.

    1982-12-01

    The following problems in experimental and theoretical investigations of heavy-ion reactions and the dynamics of nuclear fission processes are discussed: (1) emission of fast light particles in heavy-ion collisions, preequilibrium effects; (2) dynamics of deep inelastic heavy-ion reactions; (3) selected topics in quasi-elastic heavy-ion collisions; and (4) collective transport theory for fission, cross sections and neutron spectra of fission. Problems of neutron induced reactions and nuclear data evaluation are also covered. (author)

  20. Analysis of propeller-induced ground vortices by particle image velocimetry

    NARCIS (Netherlands)

    Yang, Y.; Sciacchitano, A.; Veldhuis, L.L.M.; Eitelberg, G.

    2017-01-01

    Abstract: The interaction between a propeller and its self-induced vortices originating on the ground is investigated in a scaled experiment. The velocity distribution in the flow field in two different planes containing the self-induced vortices is measured by particle image velocimetry (PIV).

  1. Analysis of heavy metals in road-deposited sediments.

    Science.gov (United States)

    Herngren, Lars; Goonetilleke, Ashantha; Ayoko, Godwin A

    2006-07-07

    Road-deposited sediments were analysed for heavy metal concentrations at three different landuses (residential, industrial, commercial) in Queensland State, Australia. The sediments were collected using a domestic vacuum cleaner which was proven to be highly efficient in collecting sub-micron particles. Five particle sizes were analysed separately for eight heavy metal elements (Zn, Fe, Pb, Cd, Cu, Cr, Al and Mn). At all sites, the maximum concentration of the heavy metals occurred in the 0.45-75 microm particle size range, which conventional street cleaning services do not remove efficiently. Multicriteria decision making methods (MCDM), PROMETHEE and GAIA, were employed in the data analysis. PROMETHEE, a non-parametric ranking analysis procedure, was used to rank the metal contents of the sediments sampled at each site. The most polluted site and particle size range were the industrial site and the 0.45-75 microm range, respectively. Although the industrial site displayed the highest metal concentrations, the highest heavy metal loading coincided with the highest sediment load, which occurred at the commercial site. GAIA, a special form of principal component analysis, was applied to determine correlations between the heavy metals and particle size ranges and also to assess possible correlation with total organic carbon (TOC). The GAIA-planes revealed that irrespective of the site, most of the heavy metals are adsorbed to sediments below 150 microm. A weak correlation was found between Zn, Mn and TOC at the commercial site. This could lead to higher bioavailability of these metals through complexation reactions with the organic species in the sediments.

  2. Exhaust particle and NOx emission performance of an SCR heavy duty truck operating in real-world conditions

    Science.gov (United States)

    Saari, Sampo; Karjalainen, Panu; Ntziachristos, Leonidas; Pirjola, Liisa; Matilainen, Pekka; Keskinen, Jorma; Rönkkö, Topi

    2016-02-01

    Particle and NOx emissions of an SCR equipped HDD truck were studied in real-world driving conditions using the "Sniffer" mobile laboratory. Real-time CO2 measurement enables emission factor calculation for NOx and particles. In this study, we compared three different emission factor calculation methods and characterised their suitability for real-world chasing experiments. The particle number emission was bimodal and dominated by the nucleation mode particles (diameter below 23 nm) having emission factor up to 1 × 1015 #/kgfuel whereas emission factor for soot (diameter above 23 nm that is consistent with the PMP standard) was typically 1 × 1014 #/kgfuel. The effect of thermodenuder on the exhaust particles indicated that the nucleation particles consisted mainly of volatile compounds, but sometimes there also existed a non-volatile core. The nucleation mode particles are not controlled by current regulations in Europe. However, these particles consistently form under atmospheric dilution in the plume of the truck and constitute a health risk for the human population that is exposed to those. Average NOx emission was 3.55 g/kWh during the test, whereas the Euro IV emission limit over transient testing is 3.5 g NOx/kWh. The on-road emission performance of the vehicle was very close to the expected levels, confirming the successful operation of the SCR system of the tested vehicle. Heavy driving conditions such as uphill driving increased both the NOx and particle number emission factors whereas the emission factor for soot particle number remains rather constant.

  3. Differential superiority of heavy charged-particle irradiation to x-rays: Studies on biological effectivenes and side effect mechanisms in multicellular tumor and normal tissue models

    Directory of Open Access Journals (Sweden)

    Stefan eWalenta

    2016-02-01

    Full Text Available This review is focused on the radiobiology of carbon ions compared to x-rays using multicellular models of tumors and normal mucosa. The first part summarizes basic radiobiological effects, as observed in cancer cells. The second, more clinically oriented part of the review deals with radiation-induced cell migration and mucositis.Multicellular spheroids (MCS from V79 hamster cells were irradiated with x-rays or carbon ions under ambient or restricted oxygen supply conditions. Oxygen enhancement ratios (OER were 2.9, 2.8, and 1.4 for irradiation with photons, 12C+6 in the plateau region, and 12C+6 in the Bragg peak, respectively. A relative biological effectiveness (RBE of 4.3 and 2.1 for ambient pO2 and hypoxia was obtained, respectively. The high effectiveness of carbon ions was reflected by an enhanced accumulation of cells in G2/M, and a dose-dependent massive induction of apoptosis. Clinically relevant doses (3 Gy of x-rays induced an increase in migratory activity of U87 but not of LN229 or HCT116 tumor cells. Such an increase in cell motility following irradiation in situ could be the source of recurrence. In contrast, carbon ion treatment was associated with a dose-dependent decrease in migration with all cell lines and under all conditions investigated. The radiation-induced loss of cell motility was correlated, in most cases, with corresponding changes in 1 integrin expression. Unlike with particles, the photon-induced increase in cell migration was paralleled by an elevated phosphorylation status of the epidermal growth factor receptor (EGFR and AKT-ERK1/2 pathway. Comparing the gene toxicity of x-rays with that of particles using the gamma-H2AX technique in organotypic cultures of the oral mucosa, the superior effectiveness of heavy ions was confirmed by a two-fold higher number of foci per nucleus. Pro-inflammatory signs, however, were similar for both treatment modalities, e. g., the activation of NFkappaB, and the release of IL

  4. Effect of heavy ion irradiation on thermodynamically equilibrium Zr-Excel alloy

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Hongbing [Department of Mechanical and Materials Engineering, Queen' s University, Kingston, ON, K7L 3N6 (Canada); Liang, Jianlie [Department of Mechanical and Materials Engineering, Queen' s University, Kingston, ON, K7L 3N6 (Canada); College of Science, Guangxi University for Nationalities, 188, East Da Xue Rd., Nanning, Guangxi, 530006 P.R.C (China); Yao, Zhongwen, E-mail: yaoz@queensu.ca [Department of Mechanical and Materials Engineering, Queen' s University, Kingston, ON, K7L 3N6 (Canada); Kirk, Mark A. [Material Science Division Argonne National Laboratory, Argonne, IL 60439 (United States); Daymond, Mark R., E-mail: mark.daymond@queensu.ca [Department of Mechanical and Materials Engineering, Queen' s University, Kingston, ON, K7L 3N6 (Canada)

    2017-05-15

    The thermodynamically equilibrium state was achieved in a Zr-Sn-Nb-Mo alloy by long-term annealing at an intermediate temperature. The fcc intermetallic Zr(Mo, Nb){sub 2} enriched with Fe was observed at the equilibrium state. In-situ 1 MeV Kr{sup 2+} heavy ion irradiation was performed in a TEM to study the stability of the intermetallic particles under irradiation and the effects of the intermetallic particle on the evolution of type dislocation loops at different temperatures from 80 to 550 °C. Chemi-STEM elemental maps were made at the same particles before and after irradiation up to 10 dpa. It was found that no elemental redistribution occurs at 200 °C and below. Selective depletion of Fe was observed from some precipitates under irradiation at higher temperatures. No change in the morphology of particles and no evidence showing a crystalline to amorphous transformation were observed at all irradiation temperatures. The formation of type dislocation loops was observed under irradiation at 80 and 200 °C, but not at 450 and 550 °C. The loops were non-uniformly distributed; a localized high density of type dislocation loops were observed near the second phase particles; we suggest that loop nucleation is favored as a result of the stress induced by the particles, rather than by elemental redistribution. The stability of the second phase particles and the formation of the type loops under heavy ion irradiation are discussed.

  5. Epstein–Barr virus particles induce centrosome amplification and chromosomal instability

    Science.gov (United States)

    Shumilov, Anatoliy; Tsai, Ming-Han; Schlosser, Yvonne T.; Kratz, Anne-Sophie; Bernhardt, Katharina; Fink, Susanne; Mizani, Tuba; Lin, Xiaochen; Jauch, Anna; Mautner, Josef; Kopp-Schneider, Annette; Feederle, Regina; Hoffmann, Ingrid; Delecluse, Henri-Jacques

    2017-01-01

    Infections with Epstein–Barr virus (EBV) are associated with cancer development, and EBV lytic replication (the process that generates virus progeny) is a strong risk factor for some cancer types. Here we report that EBV infection of B-lymphocytes (in vitro and in a mouse model) leads to an increased rate of centrosome amplification, associated with chromosomal instability. This effect can be reproduced with virus-like particles devoid of EBV DNA, but not with defective virus-like particles that cannot infect host cells. Viral protein BNRF1 induces centrosome amplification, and BNRF1-deficient viruses largely lose this property. These findings identify a new mechanism by which EBV particles can induce chromosomal instability without establishing a chronic infection, thereby conferring a risk for development of tumours that do not necessarily carry the viral genome. PMID:28186092

  6. Analysis of charged particle induced reactions for beam monitor applications

    Energy Technology Data Exchange (ETDEWEB)

    Surendra Babu, K. [IOP, Academia Sinica, Taipe, Taiwan (China); Lee, Young-Ouk [Nuclear Data Evaluation Laboratory, Korea Atomic Energy Research Institute (Korea, Republic of); Mukherjee, S., E-mail: smukherjee_msuphy@yahoo.co.in [Department of Physics, Faculty of Science, M.S. University of Baroda, Vadodara 390 002 (India)

    2012-07-15

    The reaction cross sections for different residual nuclides produced in the charged particle (p, d, {sup 3}He and {alpha}) induced reactions were calculated and compared with the existing experimental data which are important for beam monitoring and medical diagnostic applications. A detailed literature compilation and comparison were made on the available data sets for the above reactions. These calculations were carried out using the statistical model code TALYS up to 100 MeV, which contains Kalbach's latest systematic for the emission of complex particles and complex particle-induced reactions. All optical model calculations were performed by ECIS-03, which is built into TALYS. The level density, optical model potential parameters were adjusted to get the better description of experimental data. Various pre-equilibrium models were used in the present calculations with default parameters.

  7. Particle number and particulate mass emissions of heavy duty vehicles in real operating conditions

    Directory of Open Access Journals (Sweden)

    Rymaniak Lukasz

    2017-01-01

    Full Text Available The article investigates the issue of PM emissions from HDV vehicles. The theoretical part discusses the problem of emission of this toxic compound in terms of particle structure taking into account the mass and dimensions of PM. Next, the methodology of the research and the results of the measurements performed under the conditions of actual operation were presented. The test drive routes were chosen in accordance with the operational purpose of the selected test vehicles. Two heavy vehicles were used for the study: a tractor with trailer and an eighteen meter long city bus. The test vehicles complied with the Euro V standard, with the second vehicle additionally complying with the EEV standard and being equipped with a DPF. The analysis of the research results was performed in the aspect of determining the operating time densities of vehicles and their drive systems as well as defining their emission characteristics and ecological indicators. PM and PN emissions were measured in the tests and particle size distribution was determined. It was shown that the exhaust gas after treatment system used in the city bus had a positive influence on the ecological indicators and had contributed to the reduction of PN emissions for heavier particles.

  8. High energy hadron-induced errors in memory chips

    Energy Technology Data Exchange (ETDEWEB)

    Peterson, R.J. [University of Colorado, Boulder, CO (United States)

    2001-09-01

    We have measured probabilities for proton, neutron and pion beams from accelerators to induce temporary or soft errors in a wide range of modern 16 Mb and 64 Mb dRAM memory chips, typical of those used in aircraft electronics. Relations among the cross sections for these particles are deduced, and failure rates for aircraft avionics due to cosmic rays are evaluated. Measurement of alpha pha particle yields from pions on aluminum, as a surrogate for silicon, indicate that these reaction products are the proximate cause of the charge deposition resulting in errors. Heavy ions can cause damage to solar panels and other components in satellites above the atmosphere, by the heavy ionization trails they leave. However, at the earth's surface or at aircraft altitude it is known that cosmic rays, other than heavy ions, can cause soft errors in memory circuit components. Soft errors are those confusions between ones and zeroes that cause wrong contents to be stored in the memory, but without causing permanent damage to the circuit. As modern aircraft rely increasingly upon computerized and automated systems, these soft errors are important threats to safety. Protons, neutrons and pions resulting from high energy cosmic ray bombardment of the atmosphere pervade our environment. These particles do not induce damage directly by their ionization loss, but rather by reactions in the materials of the microcircuits. We have measured many cross sections for soft error upsets (SEU) in a broad range of commercial 16 Mb and 64 Mb dRAMs with accelerator beams. Here we define {sigma} SEU = induced errors/number of sample bits x particles/cm{sup 2}. We compare {sigma} SEU to find relations among results for these beams, and relations to reaction cross sections in order to systematize effects. We have modelled cosmic ray effects upon the components we have studied. (Author)

  9. High energy hadron-induced errors in memory chips

    International Nuclear Information System (INIS)

    Peterson, R.J.

    2001-01-01

    We have measured probabilities for proton, neutron and pion beams from accelerators to induce temporary or soft errors in a wide range of modern 16 Mb and 64 Mb dRAM memory chips, typical of those used in aircraft electronics. Relations among the cross sections for these particles are deduced, and failure rates for aircraft avionics due to cosmic rays are evaluated. Measurement of alpha pha particle yields from pions on aluminum, as a surrogate for silicon, indicate that these reaction products are the proximate cause of the charge deposition resulting in errors. Heavy ions can cause damage to solar panels and other components in satellites above the atmosphere, by the heavy ionization trails they leave. However, at the earth's surface or at aircraft altitude it is known that cosmic rays, other than heavy ions, can cause soft errors in memory circuit components. Soft errors are those confusions between ones and zeroes that cause wrong contents to be stored in the memory, but without causing permanent damage to the circuit. As modern aircraft rely increasingly upon computerized and automated systems, these soft errors are important threats to safety. Protons, neutrons and pions resulting from high energy cosmic ray bombardment of the atmosphere pervade our environment. These particles do not induce damage directly by their ionization loss, but rather by reactions in the materials of the microcircuits. We have measured many cross sections for soft error upsets (SEU) in a broad range of commercial 16 Mb and 64 Mb dRAMs with accelerator beams. Here we define σ SEU = induced errors/number of sample bits x particles/cm 2 . We compare σ SEU to find relations among results for these beams, and relations to reaction cross sections in order to systematize effects. We have modelled cosmic ray effects upon the components we have studied. (Author)

  10. Heavy particle decay studies using different versions of nuclear potentials

    Science.gov (United States)

    Santhosh, K. P.; Sukumaran, Indu

    2017-10-01

    The heavy particle decay from 212-240Pa , 219-245Np , 228-246Pu , 230-249Am , and 232-252Cm leading to doubly magic 208Pb and its neighboring nuclei have been studied using fourteen versions of nuclear potentials. The study has shown that the barrier penetrability as well as the decay half-lives are found to vary with the nuclear potential used. The investigated decay events of the emission of the clusters 22Ne , 24Ne , 26Mg , 28Mg , 32Si and 33Si are not experimentally detected yet but may be detectable in the future. As most of the half-lives predicted are found to lie within the experimental upper limit, T 1/2 parents with varying slopes and intercepts. Also, it is to be noted that the linearity of the GN plots is unaltered using different nuclear potentials. The universal curve studied ( log10 T 1/2 vs. -ln P for various clusters emitted from various parents shows a linear behavior with the same slope and intercept irrespective of the nuclear potential used.

  11. Heavy-ion induced multinucleon transfer reactions in the 2s--1d shell

    International Nuclear Information System (INIS)

    Olmer, C.

    1975-01-01

    In order to investigate whether new nuclear structure information can be obtained from studying the direct transfer of more than two nucleons using heavy-ion projectiles, we have investigated the 28 Si( 16 O, 12 C) 32 S and 12 C( 14 N,d) 24 Mg reactions as candidates for the direct transfer of four- and twelve-nucleons, respectively. The counter telescope-position sensitive detector kinematic coincidence method--both angular distributions (22 0 less than theta/sub L/ less than 95 0 , E/sub L/ = 55.54 MeV) and excitation functions (theta/sub L/ = 26 0 , 50 less than E/sub L/ less than 63 MeV) were obtained for strongly excited states below 10 MeV in excitation in the first reaction. For the 12 C + 14 N interaction, a measurement of the angular distributions (25 0 less than theta/sub L/ less than 140 0 , E/sub L/ = 20,25 MeV) for proton, deuteron and alpha-particle emission to many low-lying states sufficed for the present purposes. Comparison of Hauser-Feshbach statistical model calculations with these data indicated that the light-particle production from the 12 C + 14 N interaction as investigated here is predominantly compound nuclear in nature. The selectively strong population of a few states in 32 S by the 28 Si-( 16 O, 12 C) 32 S reaction is primarily direct. The structure of these states was deduced from available light-ion-induced transfer reaction studies and shell model calculations; the importance of shell model configurations is indicated, and an alpha-particle transfer model can not account for the observed selectivity. Calculations of the 28 Si( 16 O, 12 C) 32 S reaction with a microscopic multinucleon transfer code indicate selectivities consistent with the present results. Moreover, the calculations suggest the presence of other, unexpected selectivities, all of which may be understood on a physical basis, and some of which appear as an extension of a similar effect seen in two-nucleon transfer reactions

  12. Heavy metal pollution decreases microbial abundance, diversity and activity within particle-size fractions of a paddy soil.

    Science.gov (United States)

    Chen, Junhui; He, Feng; Zhang, Xuhui; Sun, Xuan; Zheng, Jufeng; Zheng, Jinwei

    2014-01-01

    Chemical and microbial characterisations of particle-size fractions (PSFs) from a rice paddy soil subjected to long-term heavy metal pollution (P) and nonpolluted (NP) soil were performed to investigate whether the distribution of heavy metals (Cd, Cu, Pb and Zn) regulates microbial community activity, abundance and diversity at the microenvironment scale. The soils were physically fractionated into coarse sand, fine sand, silt and clay fractions. Long-term heavy metal pollution notably decreased soil basal respiration (a measurement of the total activity of the soil microbial community) and microbial biomass carbon (MBC) across the fractions by 3-45% and 21-53%, respectively. The coarse sand fraction was more affected by pollution than the clay fraction and displayed a significantly lower MBC content and respiration and dehydrogenase activity compared with the nonpolluted soils. The abundances and diversities of bacteria were less affected within the PSFs under pollution. However, significant decreases in the abundances and diversities of fungi were noted, which may have strongly contributed to the decrease in MBC. Sequencing of denaturing gradient gel electrophoresis bands revealed that the groups Acidobacteria, Ascomycota and Chytridiomycota were clearly inhibited under pollution. Our findings suggest that long-term heavy metal pollution decreased the microbial biomass, activity and diversity in PSFs, particularly in the large-size fractions. © 2013 Federation of European Microbiological Societies. Published by John Wiley & Sons Ltd. All rights reserved.

  13. Experimental and theoretical study of heavy ion slowing down in solid targets

    International Nuclear Information System (INIS)

    Mehana, A.

    1993-06-01

    Heavy ion energy losses in C, Al, Cu, Ag, Ta and Au solid targets have been measured at high energy (0.2 to 5 MeV/u), using the backward secondary ion technique, and at low energy (0.1 to 0.25 MeV/u) for the C, N and O ions, using the particle backscatter method. A brief review of the various matter-induced charged particle slowing down theories, and especially the Lindhard dielectric theory, is first presented. Then, the various models for the evaluation of the effective charge and of the high order correction, are discussed and compared. Experimental techniques and data processing methods are described, and the experimental results are compared to calculations derived from the dielectric theory. In particular, the effective charges and the high order corrections (Barkas-Bloch) are examined and compared to the models for the determination of the z 3 and z 4 terms for heavy ions

  14. Lateral Tension-Induced Penetration of Particles into a Liposome

    Directory of Open Access Journals (Sweden)

    Kazuki Shigyou

    2017-07-01

    Full Text Available It is important that we understand the mechanism of the penetration of particles into a living cell to achieve advances in bionanotechnology, such as for treatment, visualization within a cell, and genetic modification. Although there have been many studies on the application of functional particles to cells, the basic mechanism of penetration across a biological membrane is still poorly understood. Here we used a model membrane system to demonstrate that lateral membrane tension drives particle penetration across a lipid bilayer. After the application of osmotic pressure, fully wrapped particles on a liposome surface were found to enter the liposome. We discuss the mechanism of the tension-induced penetration in terms of narrow constriction of the membrane at the neck part. The present findings are expected to provide insight into the application of particles to biological systems.

  15. Efimov States of Heavy Impurities in a Bose-Einstein Condensate

    DEFF Research Database (Denmark)

    Zinner, Nikolaj Thomas

    2013-01-01

    We consider the problem of two heavy impurity particles embedded in a gas of weakly-interacting light mass bosonic particles in the condensed state. Using the Bogoliubov approach to describe the bosonic gas and the Born-Oppenheimer approximation for the three-body dynamics, we calculate the modif......We consider the problem of two heavy impurity particles embedded in a gas of weakly-interacting light mass bosonic particles in the condensed state. Using the Bogoliubov approach to describe the bosonic gas and the Born-Oppenheimer approximation for the three-body dynamics, we calculate...... the modification to the heavy-heavy two-body potential due to the presence of the condensate. For the case of resonant interaction between the light bosons and the impurities, we present (semi)-analytical results for the potential in the limit of a large condensate coherence length. In particular, we find...

  16. Heavy metals induce oxidative stress and trigger oxidative stress-mediated heat shock protein (hsp) modulation in the intertidal copepod Tigriopus japonicus.

    Science.gov (United States)

    Kim, Bo-Mi; Rhee, Jae-Sung; Jeong, Chang-Bum; Seo, Jung Soo; Park, Gyung Soo; Lee, Young-Mi; Lee, Jae-Seong

    2014-11-01

    Heat shock proteins (hsps) are induced by a wide range of environmental stressors including heavy metals in aquatic organisms. However, the effect of heavy metals on zooplankton at the molecular level remains still unclear. In this study, we measured the intracellular reactive oxygen species (ROS) level and the antioxidant enzyme activities for 96 h after exposure to five heavy metals: arsenic (As), cadmium (Cd), copper (Cu), silver (Ag), and zinc (Zn) in the intertidal copepod Tigriopus japonicus. Activities of the antioxidant enzymes were highly elevated in metal-exposed copepods, indicating that heavy metals can induce oxidative stress by generating ROS, and stimulate the involvement of antioxidant enzymes as cellular defense mechanisms. Subsequently, transcriptional changes in hsp gene families were further investigated in the metal-exposed groups for 96 h. The ROS level and glutathione (GSH) content were significantly increased in Ag-, As-, and Cu-exposed copepods, while they were only slightly elevated in Cd- and Zn-exposed groups. Based on the numbers of significantly modulated hsp genes and their expression levels for 96 h, we measured the effect of heavy metals to stress genes of T. japonicus in the following order: Cu > Zn > Ag > As > Cd, implying that Cu acts as a stronger oxidative stress inducer than other heavy metals. Of them, the expression of hsp20 and hsp70 genes was substantially modulated by exposure to heavy metals, indicating that these genes would provide a sensitive molecular biomarker for aquatic monitoring of heavy metal pollution. Copyright © 2014 Elsevier Inc. All rights reserved.

  17. Quantitative laser-induced fluorescence measurements of nitric oxide in a heavy-duty Diesel engine

    NARCIS (Netherlands)

    Verbiezen, K.; Klein-Douwel, R. J. H.; van Viet, A. P.; Donkerbroek, A. J.; Meerts, W. L.; Dam, N. J.; ter Meulen, J. J.

    2007-01-01

    We present quantitative, in-cylinder, UV-laser-induced fluorescence measurements of nitric oxide in a heavy-duty Diesel engine. Processing of the raw fluorescence signals includes a detailed correction, based on additional measurements, for the effect of laser beam and fluorescence attenuation, and

  18. Search for heavy long-lived multi-charged particles in $pp$ collisions at $\\sqrt{s}$=8 TeV using the ATLAS detector

    CERN Document Server

    Aad, Georges; Abdallah, Jalal; Abdinov, Ovsat; Aben, Rosemarie; Abolins, Maris; AbouZeid, Ossama; Abramowicz, Halina; Abreu, Henso; Abreu, Ricardo; Abulaiti, Yiming; Acharya, Bobby Samir; Adamczyk, Leszek; Adams, David; Adelman, Jahred; Adomeit, Stefanie; Adye, Tim; Affolder, Tony; Agatonovic-Jovin, Tatjana; Aguilar-Saavedra, Juan Antonio; Ahlen, Steven; Ahmadov, Faig; Aielli, Giulio; Akerstedt, Henrik; Åkesson, Torsten Paul Ake; Akimoto, Ginga; Akimov, Andrei; Alberghi, Gian Luigi; Albert, Justin; Albrand, Solveig; Alconada Verzini, Maria Josefina; Aleksa, Martin; Aleksandrov, Igor; Alexa, Calin; Alexander, Gideon; Alexopoulos, Theodoros; Alhroob, Muhammad; Alimonti, Gianluca; Alio, Lion; Alison, John; Alkire, Steven Patrick; Allbrooke, Benedict; Allport, Phillip; Aloisio, Alberto; Alonso, Alejandro; Alonso, Francisco; Alpigiani, Cristiano; Altheimer, Andrew David; Alvarez Gonzalez, Barbara; Άlvarez Piqueras, Damián; Alviggi, Mariagrazia; Amako, Katsuya; Amaral Coutinho, Yara; Amelung, Christoph; Amidei, Dante; Amor Dos Santos, Susana Patricia; Amorim, Antonio; Amoroso, Simone; Amram, Nir; Amundsen, Glenn; Anastopoulos, Christos; Ancu, Lucian Stefan; Andari, Nansi; Andeen, Timothy; Anders, Christoph Falk; Anders, Gabriel; Anders, John Kenneth; Anderson, Kelby; Andreazza, Attilio; Andrei, George Victor; Angelidakis, Stylianos; Angelozzi, Ivan; Anger, Philipp; Angerami, Aaron; Anghinolfi, Francis; Anisenkov, Alexey; Anjos, Nuno; Annovi, Alberto; Antonelli, Mario; Antonov, Alexey; Antos, Jaroslav; Anulli, Fabio; Aoki, Masato; Aperio Bella, Ludovica; Arabidze, Giorgi; Arai, Yasuo; Araque, Juan Pedro; Arce, Ayana; Arduh, Francisco Anuar; Arguin, Jean-Francois; Argyropoulos, Spyridon; Arik, Metin; Armbruster, Aaron James; Arnaez, Olivier; Arnal, Vanessa; Arnold, Hannah; Arratia, Miguel; Arslan, Ozan; Artamonov, Andrei; Artoni, Giacomo; Asai, Shoji; Asbah, Nedaa; Ashkenazi, Adi; Åsman, Barbro; Asquith, Lily; Assamagan, Ketevi; Astalos, Robert; Atkinson, Markus; Atlay, Naim Bora; Auerbach, Benjamin; Augsten, Kamil; Aurousseau, Mathieu; Avolio, Giuseppe; Axen, Bradley; Ayoub, Mohamad Kassem; Azuelos, Georges; Baak, Max; Baas, Alessandra; Bacci, Cesare; Bachacou, Henri; Bachas, Konstantinos; Backes, Moritz; Backhaus, Malte; Bagiacchi, Paolo; Bagnaia, Paolo; Bai, Yu; Bain, Travis; Baines, John; Baker, Oliver Keith; Balek, Petr; Balestri, Thomas; Balli, Fabrice; Banas, Elzbieta; Banerjee, Swagato; Bannoura, Arwa A E; Bansil, Hardeep Singh; Barak, Liron; Barberio, Elisabetta Luigia; Barberis, Dario; Barbero, Marlon; Barillari, Teresa; Barisonzi, Marcello; Barklow, Timothy; Barlow, Nick; Barnes, Sarah Louise; Barnett, Bruce; Barnett, Michael; Barnovska, Zuzana; Baroncelli, Antonio; Barone, Gaetano; Barr, Alan; Barreiro, Fernando; Barreiro Guimarães da Costa, João; Bartoldus, Rainer; Barton, Adam Edward; Bartos, Pavol; Basalaev, Artem; Bassalat, Ahmed; Basye, Austin; Bates, Richard; Batista, Santiago Juan; Batley, Richard; Battaglia, Marco; Bauce, Matteo; Bauer, Florian; Bawa, Harinder Singh; Beacham, James Baker; Beattie, Michael David; Beau, Tristan; Beauchemin, Pierre-Hugues; Beccherle, Roberto; Bechtle, Philip; Beck, Hans Peter; Becker, Anne Kathrin; Becker, Maurice; Becker, Sebastian; Beckingham, Matthew; Becot, Cyril; Beddall, Andrew; Beddall, Ayda; Bednyakov, Vadim; Bee, Christopher; Beemster, Lars; Beermann, Thomas; Begel, Michael; Behr, Janna Katharina; Belanger-Champagne, Camille; Bell, William; Bella, Gideon; Bellagamba, Lorenzo; Bellerive, Alain; Bellomo, Massimiliano; Belotskiy, Konstantin; Beltramello, Olga; Benary, Odette; Benchekroun, Driss; Bender, Michael; Bendtz, Katarina; Benekos, Nektarios; Benhammou, Yan; Benhar Noccioli, Eleonora; Benitez Garcia, Jorge-Armando; Benjamin, Douglas; Bensinger, James; Bentvelsen, Stan; Beresford, Lydia; Beretta, Matteo; Berge, David; Bergeaas Kuutmann, Elin; Berger, Nicolas; Berghaus, Frank; Beringer, Jürg; Bernard, Clare; Bernard, Nathan Rogers; Bernius, Catrin; Bernlochner, Florian Urs; Berry, Tracey; Berta, Peter; Bertella, Claudia; Bertoli, Gabriele; Bertolucci, Federico; Bertsche, Carolyn; Bertsche, David; Besana, Maria Ilaria; Besjes, Geert-Jan; Bessidskaia Bylund, Olga; Bessner, Martin Florian; Besson, Nathalie; Betancourt, Christopher; Bethke, Siegfried; Bevan, Adrian John; Bhimji, Wahid; Bianchi, Riccardo-Maria; Bianchini, Louis; Bianco, Michele; Biebel, Otmar; Bieniek, Stephen Paul; Biglietti, Michela; Bilbao De Mendizabal, Javier; Bilokon, Halina; Bindi, Marcello; Binet, Sebastien; Bingul, Ahmet; Bini, Cesare; Black, Curtis; Black, James; Black, Kevin; Blackburn, Daniel; Blair, Robert; Blanchard, Jean-Baptiste; Blanco, Jacobo Ezequiel; Blazek, Tomas; Bloch, Ingo; Blocker, Craig; Blum, Walter; Blumenschein, Ulrike; Bobbink, Gerjan; Bobrovnikov, Victor; Bocchetta, Simona Serena; Bocci, Andrea; Bock, Christopher; Boehler, Michael; Bogaerts, Joannes Andreas; Bogdanchikov, Alexander; Bohm, Christian; Boisvert, Veronique; Bold, Tomasz; Boldea, Venera; Boldyrev, Alexey; Bomben, Marco; Bona, Marcella; Boonekamp, Maarten; Borisov, Anatoly; Borissov, Guennadi; Borroni, Sara; Bortfeldt, Jonathan; Bortolotto, Valerio; Bos, Kors; Boscherini, Davide; Bosman, Martine; Boudreau, Joseph; Bouffard, Julian; Bouhova-Thacker, Evelina Vassileva; Boumediene, Djamel Eddine; Bourdarios, Claire; Bousson, Nicolas; Boveia, Antonio; Boyd, James; Boyko, Igor; Bozic, Ivan; Bracinik, Juraj; Brandt, Andrew; Brandt, Gerhard; Brandt, Oleg; Bratzler, Uwe; Brau, Benjamin; Brau, James; Braun, Helmut; Brazzale, Simone Federico; Brendlinger, Kurt; Brennan, Amelia Jean; Brenner, Lydia; Brenner, Richard; Bressler, Shikma; Bristow, Kieran; Bristow, Timothy Michael; Britton, Dave; Britzger, Daniel; Brochu, Frederic; Brock, Ian; Brock, Raymond; Bronner, Johanna; Brooijmans, Gustaaf; Brooks, Timothy; Brooks, William; Brosamer, Jacquelyn; Brost, Elizabeth; Brown, Jonathan; Bruckman de Renstrom, Pawel; Bruncko, Dusan; Bruneliere, Renaud; Bruni, Alessia; Bruni, Graziano; Bruschi, Marco; Bryngemark, Lene; Buanes, Trygve; Buat, Quentin; Buchholz, Peter; Buckley, Andrew; Buda, Stelian Ioan; Budagov, Ioulian; Buehrer, Felix; Bugge, Lars; Bugge, Magnar Kopangen; Bulekov, Oleg; Bullock, Daniel; Burckhart, Helfried; Burdin, Sergey; Burghgrave, Blake; Burke, Stephen; Burmeister, Ingo; Busato, Emmanuel; Büscher, Daniel; Büscher, Volker; Bussey, Peter; Butler, John; Butt, Aatif Imtiaz; Buttar, Craig; Butterworth, Jonathan; Butti, Pierfrancesco; Buttinger, William; Buzatu, Adrian; Buzykaev, Aleksey; Cabrera Urbán, Susana; Caforio, Davide; Cairo, Valentina; Cakir, Orhan; Calafiura, Paolo; Calandri, Alessandro; Calderini, Giovanni; Calfayan, Philippe; Caloba, Luiz; Calvet, David; Calvet, Samuel; Camacho Toro, Reina; Camarda, Stefano; Camarri, Paolo; Cameron, David; Caminada, Lea Michaela; Caminal Armadans, Roger; Campana, Simone; Campanelli, Mario; Campoverde, Angel; Canale, Vincenzo; Canepa, Anadi; Cano Bret, Marc; Cantero, Josu; Cantrill, Robert; Cao, Tingting; Capeans Garrido, Maria Del Mar; Caprini, Irinel; Caprini, Mihai; Capua, Marcella; Caputo, Regina; Cardarelli, Roberto; Carli, Tancredi; Carlino, Gianpaolo; Carminati, Leonardo; Caron, Sascha; Carquin, Edson; Carrillo-Montoya, German D; Carter, Janet; Carvalho, João; Casadei, Diego; Casado, Maria Pilar; Casolino, Mirkoantonio; Castaneda-Miranda, Elizabeth; Castelli, Angelantonio; Castillo Gimenez, Victoria; Castro, Nuno Filipe; Catastini, Pierluigi; Catinaccio, Andrea; Catmore, James; Cattai, Ariella; Caudron, Julien; Cavaliere, Viviana; Cavalli, Donatella; Cavalli-Sforza, Matteo; Cavasinni, Vincenzo; Ceradini, Filippo; Cerio, Benjamin; Cerny, Karel; Santiago Cerqueira, Augusto; Cerri, Alessandro; Cerrito, Lucio; Cerutti, Fabio; Cerv, Matevz; Cervelli, Alberto; Cetin, Serkant Ali; Chafaq, Aziz; Chakraborty, Dhiman; Chalupkova, Ina; Chang, Philip; Chapleau, Bertrand; Chapman, John Derek; Charlton, Dave; Chau, Chav Chhiv; Chavez Barajas, Carlos Alberto; Cheatham, Susan; Chegwidden, Andrew; Chekanov, Sergei; Chekulaev, Sergey; Chelkov, Gueorgui; Chelstowska, Magda Anna; Chen, Chunhui; Chen, Hucheng; Chen, Karen; Chen, Liming; Chen, Shenjian; Chen, Xin; Chen, Ye; Cheng, Hok Chuen; Cheng, Yangyang; Cheplakov, Alexander; Cheremushkina, Evgenia; Cherkaoui El Moursli, Rajaa; Chernyatin, Valeriy; Cheu, Elliott; Chevalier, Laurent; Chiarella, Vitaliano; Childers, John Taylor; Chiodini, Gabriele; Chisholm, Andrew; Chislett, Rebecca Thalatta; Chitan, Adrian; Chizhov, Mihail; Choi, Kyungeon; Chouridou, Sofia; Chow, Bonnie Kar Bo; Christodoulou, Valentinos; Chromek-Burckhart, Doris; Chu, Ming-Lee; Chudoba, Jiri; Chuinard, Annabelle Julia; Chwastowski, Janusz; Chytka, Ladislav; Ciapetti, Guido; Ciftci, Abbas Kenan; Cinca, Diane; Cindro, Vladimir; Cioara, Irina Antonela; Ciocio, Alessandra; Citron, Zvi Hirsh; Ciubancan, Mihai; Clark, Allan G; Clark, Brian Lee; Clark, Philip James; Clarke, Robert; Cleland, Bill; Clement, Christophe; Coadou, Yann; Cobal, Marina; Coccaro, Andrea; Cochran, James H; Coffey, Laurel; Cogan, Joshua Godfrey; Cole, Brian; Cole, Stephen; Colijn, Auke-Pieter; Collot, Johann; Colombo, Tommaso; Compostella, Gabriele; Conde Muiño, Patricia; Coniavitis, Elias; Connell, Simon Henry; Connelly, Ian; Consonni, Sofia Maria; Consorti, Valerio; Constantinescu, Serban; Conta, Claudio; Conti, Geraldine; Conventi, Francesco; Cooke, Mark; Cooper, Ben; Cooper-Sarkar, Amanda; Cornelissen, Thijs; Corradi, Massimo; Corriveau, Francois; Corso-Radu, Alina; Cortes-Gonzalez, Arely; Cortiana, Giorgio; Costa, Giuseppe; Costa, María José; Costanzo, Davide; Côté, David; Cottin, Giovanna; Cowan, Glen; Cox, Brian; Cranmer, Kyle; Cree, Graham; Crépé-Renaudin, Sabine; Crescioli, Francesco; Cribbs, Wayne Allen; Crispin Ortuzar, Mireia; Cristinziani, Markus; Croft, Vince; Crosetti, Giovanni; Cuhadar Donszelmann, Tulay; Cummings, Jane; Curatolo, Maria; Cuthbert, Cameron; Czirr, Hendrik; Czodrowski, Patrick; D'Auria, Saverio; D'Onofrio, Monica; Da Cunha Sargedas De Sousa, Mario Jose; Da Via, Cinzia; Dabrowski, Wladyslaw; Dafinca, Alexandru; Dai, Tiesheng; Dale, Orjan; Dallaire, Frederick; Dallapiccola, Carlo; Dam, Mogens; Dandoy, Jeffrey Rogers; Dang, Nguyen Phuong; Daniells, Andrew Christopher; Danninger, Matthias; Dano Hoffmann, Maria; Dao, Valerio; Darbo, Giovanni; Darmora, Smita; Dassoulas, James; Dattagupta, Aparajita; Davey, Will; David, Claire; Davidek, Tomas; Davies, Eleanor; Davies, Merlin; Davison, Peter; Davygora, Yuriy; Dawe, Edmund; Dawson, Ian; Daya-Ishmukhametova, Rozmin; De, Kaushik; de Asmundis, Riccardo; De Castro, Stefano; De Cecco, Sandro; De Groot, Nicolo; de Jong, Paul; De la Torre, Hector; De Lorenzi, Francesco; De Nooij, Lucie; De Pedis, Daniele; De Salvo, Alessandro; De Sanctis, Umberto; De Santo, Antonella; De Vivie De Regie, Jean-Baptiste; Dearnaley, William James; Debbe, Ramiro; Debenedetti, Chiara; Dedovich, Dmitri; Deigaard, Ingrid; Del Peso, Jose; Del Prete, Tarcisio; Delgove, David; Deliot, Frederic; Delitzsch, Chris Malena; Deliyergiyev, Maksym; Dell'Acqua, Andrea; Dell'Asta, Lidia; Dell'Orso, Mauro; Della Pietra, Massimo; della Volpe, Domenico; Delmastro, Marco; Delsart, Pierre-Antoine; Deluca, Carolina; DeMarco, David; Demers, Sarah; Demichev, Mikhail; Demilly, Aurelien; Denisov, Sergey; Derendarz, Dominik; Derkaoui, Jamal Eddine; Derue, Frederic; Dervan, Paul; Desch, Klaus Kurt; Deterre, Cecile; Deviveiros, Pier-Olivier; Dewhurst, Alastair; Dhaliwal, Saminder; Di Ciaccio, Anna; Di Ciaccio, Lucia; Di Domenico, Antonio; Di Donato, Camilla; Di Girolamo, Alessandro; Di Girolamo, Beniamino; Di Mattia, Alessandro; Di Micco, Biagio; Di Nardo, Roberto; Di Simone, Andrea; Di Sipio, Riccardo; Di Valentino, David; Diaconu, Cristinel; Diamond, Miriam; Dias, Flavia; Diaz, Marco Aurelio; Diehl, Edward; Dietrich, Janet; Diglio, Sara; Dimitrievska, Aleksandra; Dingfelder, Jochen; Dita, Petre; Dita, Sanda; Dittus, Fridolin; Djama, Fares; Djobava, Tamar; Djuvsland, Julia Isabell; Barros do Vale, Maria Aline; Dobos, Daniel; Dobre, Monica; Doglioni, Caterina; Dohmae, Takeshi; Dolejsi, Jiri; Dolezal, Zdenek; Dolgoshein, Boris; Donadelli, Marisilvia; Donati, Simone; Dondero, Paolo; Donini, Julien; Dopke, Jens; Doria, Alessandra; Dova, Maria-Teresa; Doyle, Tony; Drechsler, Eric; Dris, Manolis; Dubreuil, Emmanuelle; Duchovni, Ehud; Duckeck, Guenter; Ducu, Otilia Anamaria; Duda, Dominik; Dudarev, Alexey; Duflot, Laurent; Duguid, Liam; Dührssen, Michael; Dunford, Monica; Duran Yildiz, Hatice; Düren, Michael; Durglishvili, Archil; Duschinger, Dirk; Dyndal, Mateusz; Eckardt, Christoph; Ecker, Katharina Maria; Edgar, Ryan Christopher; Edson, William; Edwards, Nicholas Charles; Ehrenfeld, Wolfgang; Eifert, Till; Eigen, Gerald; Einsweiler, Kevin; Ekelof, Tord; El Kacimi, Mohamed; Ellert, Mattias; Elles, Sabine; Ellinghaus, Frank; Elliot, Alison; Ellis, Nicolas; Elmsheuser, Johannes; Elsing, Markus; Emeliyanov, Dmitry; Enari, Yuji; Endner, Oliver Chris; Endo, Masaki; Erdmann, Johannes; Ereditato, Antonio; Ernis, Gunar; Ernst, Jesse; Ernst, Michael; Errede, Steven; Ertel, Eugen; Escalier, Marc; Esch, Hendrik; Escobar, Carlos; Esposito, Bellisario; Etienvre, Anne-Isabelle; Etzion, Erez; Evans, Hal; Ezhilov, Alexey; Fabbri, Laura; Facini, Gabriel; Fakhrutdinov, Rinat; Falciano, Speranza; Falla, Rebecca Jane; Faltova, Jana; Fang, Yaquan; Fanti, Marcello; Farbin, Amir; Farilla, Addolorata; Farooque, Trisha; Farrell, Steven; Farrington, Sinead; Farthouat, Philippe; Fassi, Farida; Fassnacht, Patrick; Fassouliotis, Dimitrios; Faucci Giannelli, Michele; Favareto, Andrea; Fayard, Louis; Federic, Pavol; Fedin, Oleg; Fedorko, Wojciech; Feigl, Simon; Feligioni, Lorenzo; Feng, Cunfeng; Feng, Eric; Feng, Haolu; Fenyuk, Alexander; Fernandez Martinez, Patricia; Fernandez Perez, Sonia; Ferrando, James; Ferrari, Arnaud; Ferrari, Pamela; Ferrari, Roberto; Ferreira de Lima, Danilo Enoque; Ferrer, Antonio; Ferrere, Didier; Ferretti, Claudio; Ferretto Parodi, Andrea; Fiascaris, Maria; Fiedler, Frank; Filipčič, Andrej; Filipuzzi, Marco; Filthaut, Frank; Fincke-Keeler, Margret; Finelli, Kevin Daniel; Fiolhais, Miguel; Fiorini, Luca; Firan, Ana; Fischer, Adam; Fischer, Cora; Fischer, Julia; Fisher, Wade Cameron; Fitzgerald, Eric Andrew; Flechl, Martin; Fleck, Ivor; Fleischmann, Philipp; Fleischmann, Sebastian; Fletcher, Gareth Thomas; Fletcher, Gregory; Flick, Tobias; Floderus, Anders; Flores Castillo, Luis; Flowerdew, Michael; Formica, Andrea; Forti, Alessandra; Fournier, Daniel; Fox, Harald; Fracchia, Silvia; Francavilla, Paolo; Franchini, Matteo; Francis, David; Franconi, Laura; Franklin, Melissa; Fraternali, Marco; Freeborn, David; French, Sky; Friedrich, Felix; Froidevaux, Daniel; Frost, James; Fukunaga, Chikara; Fullana Torregrosa, Esteban; Fulsom, Bryan Gregory; Fuster, Juan; Gabaldon, Carolina; Gabizon, Ofir; Gabrielli, Alessandro; Gabrielli, Andrea; Gadatsch, Stefan; Gadomski, Szymon; Gagliardi, Guido; Gagnon, Pauline; Galea, Cristina; Galhardo, Bruno; Gallas, Elizabeth; Gallop, Bruce; Gallus, Petr; Galster, Gorm Aske Gram Krohn; Gan, KK; Gao, Jun; Gao, Yanyan; Gao, Yongsheng; Garay Walls, Francisca; Garberson, Ford; García, Carmen; García Navarro, José Enrique; Garcia-Sciveres, Maurice; Gardner, Robert; Garelli, Nicoletta; Garonne, Vincent; Gatti, Claudio; Gaudiello, Andrea; Gaudio, Gabriella; Gaur, Bakul; Gauthier, Lea; Gauzzi, Paolo; Gavrilenko, Igor; Gay, Colin; Gaycken, Goetz; Gazis, Evangelos; Ge, Peng; Gecse, Zoltan; Gee, Norman; Geerts, Daniël Alphonsus Adrianus; Geich-Gimbel, Christoph; Geisler, Manuel Patrice; Gemme, Claudia; Genest, Marie-Hélène; Gentile, Simonetta; George, Matthias; George, Simon; Gerbaudo, Davide; Gershon, Avi; Ghazlane, Hamid; Giacobbe, Benedetto; Giagu, Stefano; Giangiobbe, Vincent; Giannetti, Paola; Gibbard, Bruce; Gibson, Stephen; Gilchriese, Murdock; Gillam, Thomas; Gillberg, Dag; Gilles, Geoffrey; Gingrich, Douglas; Giokaris, Nikos; Giordani, MarioPaolo; Giorgi, Filippo Maria; Giorgi, Francesco Michelangelo; Giraud, Pierre-Francois; Giromini, Paolo; Giugni, Danilo; Giuliani, Claudia; Giulini, Maddalena; Gjelsten, Børge Kile; Gkaitatzis, Stamatios; Gkialas, Ioannis; Gkougkousis, Evangelos Leonidas; Gladilin, Leonid; Glasman, Claudia; Glatzer, Julian; Glaysher, Paul; Glazov, Alexandre; Goblirsch-Kolb, Maximilian; Goddard, Jack Robert; Godlewski, Jan; Goldfarb, Steven; Golling, Tobias; Golubkov, Dmitry; Gomes, Agostinho; Gonçalo, Ricardo; Goncalves Pinto Firmino Da Costa, Joao; Gonella, Laura; González de la Hoz, Santiago; Gonzalez Parra, Garoe; Gonzalez-Sevilla, Sergio; Goossens, Luc; Gorbounov, Petr Andreevich; Gordon, Howard; Gorelov, Igor; Gorini, Benedetto; Gorini, Edoardo; Gorišek, Andrej; Gornicki, Edward; Goshaw, Alfred; Gössling, Claus; Gostkin, Mikhail Ivanovitch; Goujdami, Driss; Goussiou, Anna; Govender, Nicolin; Grabas, Herve Marie Xavier; Graber, Lars; Grabowska-Bold, Iwona; Grafström, Per; Grahn, Karl-Johan; Gramling, Johanna; Gramstad, Eirik; Grancagnolo, Sergio; Grassi, Valerio; Gratchev, Vadim; Gray, Heather; Graziani, Enrico; Greenwood, Zeno Dixon; Gregersen, Kristian; Gregor, Ingrid-Maria; Grenier, Philippe; Griffiths, Justin; Grillo, Alexander; Grimm, Kathryn; Grinstein, Sebastian; Gris, Philippe Luc Yves; Grivaz, Jean-Francois; Grohs, Johannes Philipp; Grohsjean, Alexander; Gross, Eilam; Grosse-Knetter, Joern; Grossi, Giulio Cornelio; Grout, Zara Jane; Guan, Liang; Guenther, Jaroslav; Guescini, Francesco; Guest, Daniel; Gueta, Orel; Guido, Elisa; Guillemin, Thibault; Guindon, Stefan; Gul, Umar; Gumpert, Christian; Guo, Jun; Gupta, Shaun; Gutierrez, Phillip; Gutierrez Ortiz, Nicolas Gilberto; Gutschow, Christian; Guyot, Claude; Gwenlan, Claire; Gwilliam, Carl; Haas, Andy; Haber, Carl; Hadavand, Haleh Khani; Haddad, Nacim; Haefner, Petra; Hageböck, Stephan; Hajduk, Zbigniew; Hakobyan, Hrachya; Haleem, Mahsana; Haley, Joseph; Hall, David; Halladjian, Garabed; Hallewell, Gregory David; Hamacher, Klaus; Hamal, Petr; Hamano, Kenji; Hamer, Matthias; Hamilton, Andrew; Hamilton, Samuel; Hamity, Guillermo Nicolas; Hamnett, Phillip George; Han, Liang; Hanagaki, Kazunori; Hanawa, Keita; Hance, Michael; Hanke, Paul; Hanna, Remie; Hansen, Jørgen Beck; Hansen, Jorn Dines; Hansen, Maike Christina; Hansen, Peter Henrik; Hara, Kazuhiko; Hard, Andrew; Harenberg, Torsten; Hariri, Faten; Harkusha, Siarhei; Harrington, Robert; Harrison, Paul Fraser; Hartjes, Fred; Hasegawa, Makoto; Hasegawa, Satoshi; Hasegawa, Yoji; Hasib, A; Hassani, Samira; Haug, Sigve; Hauser, Reiner; Hauswald, Lorenz; Havranek, Miroslav; Hawkes, Christopher; Hawkings, Richard John; Hawkins, Anthony David; Hayashi, Takayasu; Hayden, Daniel; Hays, Chris; Hays, Jonathan Michael; Hayward, Helen; Haywood, Stephen; Head, Simon; Heck, Tobias; Hedberg, Vincent; Heelan, Louise; Heim, Sarah; Heim, Timon; Heinemann, Beate; Heinrich, Lukas; Hejbal, Jiri; Helary, Louis; Hellman, Sten; Hellmich, Dennis; Helsens, Clement; Henderson, James; Henderson, Robert; Heng, Yang; Hengler, Christopher; Henrichs, Anna; Henriques Correia, Ana Maria; Henrot-Versille, Sophie; Herbert, Geoffrey Henry; Hernández Jiménez, Yesenia; Herrberg-Schubert, Ruth; Herten, Gregor; Hertenberger, Ralf; Hervas, Luis; Hesketh, Gavin Grant; Hessey, Nigel; Hetherly, Jeffrey Wayne; Hickling, Robert; Higón-Rodriguez, Emilio; Hill, Ewan; Hill, John; Hiller, Karl Heinz; Hillier, Stephen; Hinchliffe, Ian; Hines, Elizabeth; Hinman, Rachel Reisner; Hirose, Minoru; Hirschbuehl, Dominic; Hobbs, John; Hod, Noam; Hodgkinson, Mark; Hodgson, Paul; Hoecker, Andreas; Hoeferkamp, Martin; Hoenig, Friedrich; Hohlfeld, Marc; Hohn, David; Holmes, Tova Ray; Homann, Michael; Hong, Tae Min; Hooft van Huysduynen, Loek; Hopkins, Walter; Horii, Yasuyuki; Horton, Arthur James; Hostachy, Jean-Yves; Hou, Suen; Hoummada, Abdeslam; Howard, Jacob; Howarth, James; Hrabovsky, Miroslav; Hristova, Ivana; Hrivnac, Julius; Hryn'ova, Tetiana; Hrynevich, Aliaksei; Hsu, Catherine; Hsu, Pai-hsien Jennifer; Hsu, Shih-Chieh; Hu, Diedi; Hu, Qipeng; Hu, Xueye; Huang, Yanping; Hubacek, Zdenek; Hubaut, Fabrice; Huegging, Fabian; Huffman, Todd Brian; Hughes, Emlyn; Hughes, Gareth; Huhtinen, Mika; Hülsing, Tobias Alexander; Huseynov, Nazim; Huston, Joey; Huth, John; Iacobucci, Giuseppe; Iakovidis, Georgios; Ibragimov, Iskander; Iconomidou-Fayard, Lydia; Ideal, Emma; Idrissi, Zineb; Iengo, Paolo; Igonkina, Olga; Iizawa, Tomoya; Ikegami, Yoichi; Ikematsu, Katsumasa; Ikeno, Masahiro; Ilchenko, Iurii; Iliadis, Dimitrios; Ilic, Nikolina; Inamaru, Yuki; Ince, Tayfun; Ioannou, Pavlos; Iodice, Mauro; Iordanidou, Kalliopi; Ippolito, Valerio; Irles Quiles, Adrian; Isaksson, Charlie; Ishino, Masaya; Ishitsuka, Masaki; Ishmukhametov, Renat; Issever, Cigdem; Istin, Serhat; Iturbe Ponce, Julia Mariana; Iuppa, Roberto; Ivarsson, Jenny; Iwanski, Wieslaw; Iwasaki, Hiroyuki; Izen, Joseph; Izzo, Vincenzo; Jabbar, Samina; Jackson, Brett; Jackson, Matthew; Jackson, Paul; Jaekel, Martin; Jain, Vivek; Jakobs, Karl; Jakobsen, Sune; Jakoubek, Tomas; Jakubek, Jan; Jamin, David Olivier; Jana, Dilip; Jansen, Eric; Jansky, Roland; Janssen, Jens; Janus, Michel; Jarlskog, Göran; Javadov, Namig; Javůrek, Tomáš; Jeanty, Laura; Jejelava, Juansher; Jeng, Geng-yuan; Jennens, David; Jenni, Peter; Jentzsch, Jennifer; Jeske, Carl; Jézéquel, Stéphane; Ji, Haoshuang; Jia, Jiangyong; Jiang, Yi; Jiggins, Stephen; Jimenez Pena, Javier; Jin, Shan; Jinaru, Adam; Jinnouchi, Osamu; Joergensen, Morten Dam; Johansson, Per; Johns, Kenneth; Jon-And, Kerstin; Jones, Graham; Jones, Roger; Jones, Tim; Jongmanns, Jan; Jorge, Pedro; Joshi, Kiran Daniel; Jovicevic, Jelena; Ju, Xiangyang; Jung, Christian; Jussel, Patrick; Juste Rozas, Aurelio; Kaci, Mohammed; Kaczmarska, Anna; Kado, Marumi; Kagan, Harris; Kagan, Michael; Kahn, Sebastien Jonathan; Kajomovitz, Enrique; Kalderon, Charles William; Kama, Sami; Kamenshchikov, Andrey; Kanaya, Naoko; Kaneda, Michiru; Kaneti, Steven; Kantserov, Vadim; Kanzaki, Junichi; Kaplan, Benjamin; Kapliy, Anton; Kar, Deepak; Karakostas, Konstantinos; Karamaoun, Andrew; Karastathis, Nikolaos; Kareem, Mohammad Jawad; Karnevskiy, Mikhail; Karpov, Sergey; Karpova, Zoya; Karthik, Krishnaiyengar; Kartvelishvili, Vakhtang; Karyukhin, Andrey; Kashif, Lashkar; Kass, Richard; Kastanas, Alex; Kataoka, Yousuke; Katre, Akshay; Katzy, Judith; Kawagoe, Kiyotomo; Kawamoto, Tatsuo; Kawamura, Gen; Kazama, Shingo; Kazanin, Vassili; Kazarinov, Makhail; Keeler, Richard; Kehoe, Robert; Keller, John; Kempster, Jacob Julian; Keoshkerian, Houry; Kepka, Oldrich; Kerševan, Borut Paul; Kersten, Susanne; Keyes, Robert; Khalil-zada, Farkhad; Khandanyan, Hovhannes; Khanov, Alexander; Kharlamov, Alexey; Khoo, Teng Jian; Khovanskiy, Valery; Khramov, Evgeniy; Khubua, Jemal; Kim, Hee Yeun; Kim, Hyeon Jin; Kim, Shinhong; Kim, Young-Kee; Kimura, Naoki; Kind, Oliver Maria; King, Barry; King, Matthew; King, Robert Steven Beaufoy; King, Samuel Burton; Kirk, Julie; Kiryunin, Andrey; Kishimoto, Tomoe; Kisielewska, Danuta; Kiss, Florian; Kiuchi, Kenji; Kivernyk, Oleh; Kladiva, Eduard; Klein, Matthew Henry; Klein, Max; Klein, Uta; Kleinknecht, Konrad; Klimek, Pawel; Klimentov, Alexei; Klingenberg, Reiner; Klinger, Joel Alexander; Klioutchnikova, Tatiana; Klok, Peter; Kluge, Eike-Erik; Kluit, Peter; Kluth, Stefan; Kneringer, Emmerich; Knoops, Edith; Knue, Andrea; Kobayashi, Aine; Kobayashi, Dai; Kobayashi, Tomio; Kobel, Michael; Kocian, Martin; Kodys, Peter; Koffas, Thomas; Koffeman, Els; Kogan, Lucy Anne; Kohlmann, Simon; Kohout, Zdenek; Kohriki, Takashi; Koi, Tatsumi; Kolanoski, Hermann; Koletsou, Iro; Komar, Aston; Komori, Yuto; Kondo, Takahiko; Kondrashova, Nataliia; Köneke, Karsten; König, Adriaan; König, Sebastian; Kono, Takanori; Konoplich, Rostislav; Konstantinidis, Nikolaos; Kopeliansky, Revital; Koperny, Stefan; Köpke, Lutz; Kopp, Anna Katharina; Korcyl, Krzysztof; Kordas, Kostantinos; Korn, Andreas; Korol, Aleksandr; Korolkov, Ilya; Korolkova, Elena; Kortner, Oliver; Kortner, Sandra; Kosek, Tomas; Kostyukhin, Vadim; Kotov, Vladislav; Kotwal, Ashutosh; Kourkoumeli-Charalampidi, Athina; Kourkoumelis, Christine; Kouskoura, Vasiliki; Koutsman, Alex; Kowalewski, Robert Victor; Kowalski, Tadeusz; Kozanecki, Witold; Kozhin, Anatoly; Kramarenko, Viktor; Kramberger, Gregor; Krasnopevtsev, Dimitriy; Krasny, Mieczyslaw Witold; Krasznahorkay, Attila; Kraus, Jana; Kravchenko, Anton; Kreiss, Sven; Kretz, Moritz; Kretzschmar, Jan; Kreutzfeldt, Kristof; Krieger, Peter; Krizka, Karol; Kroeninger, Kevin; Kroha, Hubert; Kroll, Joe; Kroseberg, Juergen; Krstic, Jelena; Kruchonak, Uladzimir; Krüger, Hans; Krumnack, Nils; Krumshteyn, Zinovii; Kruse, Amanda; Kruse, Mark; Kruskal, Michael; Kubota, Takashi; Kucuk, Hilal; Kuday, Sinan; Kuehn, Susanne; Kugel, Andreas; Kuger, Fabian; Kuhl, Andrew; Kuhl, Thorsten; Kukhtin, Victor; Kulchitsky, Yuri; Kuleshov, Sergey; Kuna, Marine; Kunigo, Takuto; Kupco, Alexander; Kurashige, Hisaya; Kurochkin, Yurii; Kurumida, Rie; Kus, Vlastimil; Kuwertz, Emma Sian; Kuze, Masahiro; Kvita, Jiri; Kwan, Tony; Kyriazopoulos, Dimitrios; La Rosa, Alessandro; La Rosa Navarro, Jose Luis; La Rotonda, Laura; Lacasta, Carlos; Lacava, Francesco; Lacey, James; Lacker, Heiko; Lacour, Didier; Lacuesta, Vicente Ramón; Ladygin, Evgueni; Lafaye, Remi; Laforge, Bertrand; Lagouri, Theodota; Lai, Stanley; Lambourne, Luke; Lammers, Sabine; Lampen, Caleb; Lampl, Walter; Lançon, Eric; Landgraf, Ulrich; Landon, Murrough; Lang, Valerie Susanne; Lange, J örn Christian; Lankford, Andrew; Lanni, Francesco; Lantzsch, Kerstin; Laplace, Sandrine; Lapoire, Cecile; Laporte, Jean-Francois; Lari, Tommaso; Lasagni Manghi, Federico; Lassnig, Mario; Laurelli, Paolo; Lavrijsen, Wim; Law, Alexander; Laycock, Paul; Le Dortz, Olivier; Le Guirriec, Emmanuel; Le Menedeu, Eve; LeBlanc, Matthew Edgar; LeCompte, Thomas; Ledroit-Guillon, Fabienne Agnes Marie; Lee, Claire Alexandra; Lee, Shih-Chang; Lee, Lawrence; Lefebvre, Guillaume; Lefebvre, Michel; Legger, Federica; Leggett, Charles; Lehan, Allan; Lehmann Miotto, Giovanna; Lei, Xiaowen; Leight, William Axel; Leisos, Antonios; Leister, Andrew Gerard; Leite, Marco Aurelio Lisboa; Leitner, Rupert; Lellouch, Daniel; Lemmer, Boris; Leney, Katharine; Lenz, Tatjana; Lenzi, Bruno; Leone, Robert; Leone, Sandra; Leonidopoulos, Christos; Leontsinis, Stefanos; Leroy, Claude; Lester, Christopher; Levchenko, Mikhail; Levêque, Jessica; Levin, Daniel; Levinson, Lorne; Levy, Mark; Lewis, Adrian; Leyko, Agnieszka; Leyton, Michael; Li, Bing; Li, Haifeng; Li, Ho Ling; Li, Lei; Li, Liang; Li, Shu; Li, Yichen; Liang, Zhijun; Liao, Hongbo; Liberti, Barbara; Liblong, Aaron; Lichard, Peter; Lie, Ki; Liebal, Jessica; Liebig, Wolfgang; Limbach, Christian; Limosani, Antonio; Lin, Simon; Lin, Tai-Hua; Linde, Frank; Lindquist, Brian Edward; Linnemann, James; Lipeles, Elliot; Lipniacka, Anna; Lisovyi, Mykhailo; Liss, Tony; Lissauer, David; Lister, Alison; Litke, Alan; Liu, Bo; Liu, Dong; Liu, Jian; Liu, Jianbei; Liu, Kun; Liu, Lulu; Liu, Miaoyuan; Liu, Minghui; Liu, Yanwen; Livan, Michele; Lleres, Annick; Llorente Merino, Javier; Lloyd, Stephen; Lo Sterzo, Francesco; Lobodzinska, Ewelina; Loch, Peter; Lockman, William; Loebinger, Fred; Loevschall-Jensen, Ask Emil; Loginov, Andrey; Lohse, Thomas; Lohwasser, Kristin; Lokajicek, Milos; Long, Brian Alexander; Long, Jonathan; Long, Robin Eamonn; Looper, Kristina Anne; Lopes, Lourenco; Lopez Mateos, David; Lopez Paredes, Brais; Lopez Paz, Ivan; Lorenz, Jeanette; Lorenzo Martinez, Narei; Losada, Marta; Loscutoff, Peter; Lösel, Philipp Jonathan; Lou, XinChou; Lounis, Abdenour; Love, Jeremy; Love, Peter; Lu, Nan; Lubatti, Henry; Luci, Claudio; Lucotte, Arnaud; Luehring, Frederick; Lukas, Wolfgang; Luminari, Lamberto; Lundberg, Olof; Lund-Jensen, Bengt; Lynn, David; Lysak, Roman; Lytken, Else; Ma, Hong; Ma, Lian Liang; Maccarrone, Giovanni; Macchiolo, Anna; Macdonald, Calum Michael; Machado Miguens, Joana; Macina, Daniela; Madaffari, Daniele; Madar, Romain; Maddocks, Harvey Jonathan; Mader, Wolfgang; Madsen, Alexander; Maeland, Steffen; Maeno, Tadashi; Maevskiy, Artem; Magradze, Erekle; Mahboubi, Kambiz; Mahlstedt, Joern; Maiani, Camilla; Maidantchik, Carmen; Maier, Andreas Alexander; Maier, Thomas; Maio, Amélia; Majewski, Stephanie; Makida, Yasuhiro; Makovec, Nikola; Malaescu, Bogdan; Malecki, Pawel; Maleev, Victor; Malek, Fairouz; Mallik, Usha; Malon, David; Malone, Caitlin; Maltezos, Stavros; Malyshev, Vladimir; Malyukov, Sergei; Mamuzic, Judita; Mancini, Giada; Mandelli, Beatrice; Mandelli, Luciano; Mandić, Igor; Mandrysch, Rocco; Maneira, José; Manfredini, Alessandro; Manhaes de Andrade Filho, Luciano; Manjarres Ramos, Joany; Mann, Alexander; Manning, Peter; Manousakis-Katsikakis, Arkadios; Mansoulie, Bruno; Mantifel, Rodger; Mantoani, Matteo; Mapelli, Livio; March, Luis; Marchiori, Giovanni; Marcisovsky, Michal; Marino, Christopher; Marjanovic, Marija; Marroquim, Fernando; Marsden, Stephen Philip; Marshall, Zach; Marti, Lukas Fritz; Marti-Garcia, Salvador; Martin, Brian Thomas; Martin, Tim; Martin, Victoria Jane; Martin dit Latour, Bertrand; Martinez, Mario; Martin-Haugh, Stewart; Martoiu, Victor Sorin; Martyniuk, Alex; Marx, Marilyn; Marzano, Francesco; Marzin, Antoine; Masetti, Lucia; Mashimo, Tetsuro; Mashinistov, Ruslan; Masik, Jiri; Maslennikov, Alexey; Massa, Ignazio; Massa, Lorenzo; Massol, Nicolas; Mastrandrea, Paolo; Mastroberardino, Anna; Masubuchi, Tatsuya; Mättig, Peter; Mattmann, Johannes; Maurer, Julien; Maxfield, Stephen; Maximov, Dmitriy; Mazini, Rachid; Mazza, Simone Michele; Mazzaferro, Luca; Mc Goldrick, Garrin; Mc Kee, Shawn Patrick; McCarn, Allison; McCarthy, Robert; McCarthy, Tom; McCubbin, Norman; McFarlane, Kenneth; Mcfayden, Josh; Mchedlidze, Gvantsa; McMahon, Steve; McPherson, Robert; Medinnis, Michael; Meehan, Samuel; Mehlhase, Sascha; Mehta, Andrew; Meier, Karlheinz; Meineck, Christian; Meirose, Bernhard; Mellado Garcia, Bruce Rafael; Meloni, Federico; Mengarelli, Alberto; Menke, Sven; Meoni, Evelin; Mercurio, Kevin Michael; Mergelmeyer, Sebastian; Mermod, Philippe; Merola, Leonardo; Meroni, Chiara; Merritt, Frank; Messina, Andrea; Metcalfe, Jessica; Mete, Alaettin Serhan; Meyer, Carsten; Meyer, Christopher; Meyer, Jean-Pierre; Meyer, Jochen; Middleton, Robin; Miglioranzi, Silvia; Mijović, Liza; Mikenberg, Giora; Mikestikova, Marcela; Mikuž, Marko; Milesi, Marco; Milic, Adriana; Miller, David; Mills, Corrinne; Milov, Alexander; Milstead, David; Minaenko, Andrey; Minami, Yuto; Minashvili, Irakli; Mincer, Allen; Mindur, Bartosz; Mineev, Mikhail; Ming, Yao; Mir, Lluisa-Maria; Mitani, Takashi; Mitrevski, Jovan; Mitsou, Vasiliki A; Miucci, Antonio; Miyagawa, Paul; Mjörnmark, Jan-Ulf; Moa, Torbjoern; Mochizuki, Kazuya; Mohapatra, Soumya; Mohr, Wolfgang; Molander, Simon; Moles-Valls, Regina; Mönig, Klaus; Monini, Caterina; Monk, James; Monnier, Emmanuel; Montejo Berlingen, Javier; Monticelli, Fernando; Monzani, Simone; Moore, Roger; Morange, Nicolas; Moreno, Deywis; Moreno Llácer, María; Morettini, Paolo; Morgenstern, Marcus; Morii, Masahiro; Morinaga, Masahiro; Morisbak, Vanja; Moritz, Sebastian; Morley, Anthony Keith; Mornacchi, Giuseppe; Morris, John; Mortensen, Simon Stark; Morton, Alexander; Morvaj, Ljiljana; Mosidze, Maia; Moss, Josh; Motohashi, Kazuki; Mount, Richard; Mountricha, Eleni; Mouraviev, Sergei; Moyse, Edward; Muanza, Steve; Mudd, Richard; Mueller, Felix; Mueller, James; Mueller, Klemens; Mueller, Ralph Soeren Peter; Mueller, Thibaut; Muenstermann, Daniel; Mullen, Paul; Munwes, Yonathan; Murillo Quijada, Javier Alberto; Murray, Bill; Musheghyan, Haykuhi; Musto, Elisa; Myagkov, Alexey; Myska, Miroslav; Nackenhorst, Olaf; Nadal, Jordi; Nagai, Koichi; Nagai, Ryo; Nagai, Yoshikazu; Nagano, Kunihiro; Nagarkar, Advait; Nagasaka, Yasushi; Nagata, Kazuki; Nagel, Martin; Nagy, Elemer; Nairz, Armin Michael; Nakahama, Yu; Nakamura, Koji; Nakamura, Tomoaki; Nakano, Itsuo; Namasivayam, Harisankar; Naranjo Garcia, Roger Felipe; Narayan, Rohin; Naumann, Thomas; Navarro, Gabriela; Nayyar, Ruchika; Neal, Homer; Nechaeva, Polina; Neep, Thomas James; Nef, Pascal Daniel; Negri, Andrea; Negrini, Matteo; Nektarijevic, Snezana; Nellist, Clara; Nelson, Andrew; Nemecek, Stanislav; Nemethy, Peter; Nepomuceno, Andre Asevedo; Nessi, Marzio; Neubauer, Mark; Neumann, Manuel; Neves, Ricardo; Nevski, Pavel; Newman, Paul; Nguyen, Duong Hai; Nickerson, Richard; Nicolaidou, Rosy; Nicquevert, Bertrand; Nielsen, Jason; Nikiforou, Nikiforos; Nikiforov, Andriy; Nikolaenko, Vladimir; Nikolic-Audit, Irena; Nikolopoulos, Konstantinos; Nilsen, Jon Kerr; Nilsson, Paul; Ninomiya, Yoichi; Nisati, Aleandro; Nisius, Richard; Nobe, Takuya; Nomachi, Masaharu; Nomidis, Ioannis; Nooney, Tamsin; Norberg, Scarlet; Nordberg, Markus; Novgorodova, Olga; Nowak, Sebastian; Nozaki, Mitsuaki; Nozka, Libor; Ntekas, Konstantinos; Nunes Hanninger, Guilherme; Nunnemann, Thomas; Nurse, Emily; Nuti, Francesco; O'Brien, Brendan Joseph; O'grady, Fionnbarr; O'Neil, Dugan; O'Shea, Val; Oakham, Gerald; Oberlack, Horst; Obermann, Theresa; Ocariz, Jose; Ochi, Atsuhiko; Ochoa, Ines; Ochoa-Ricoux, Juan Pedro; Oda, Susumu; Odaka, Shigeru; Ogren, Harold; Oh, Alexander; Oh, Seog; Ohm, Christian; Ohman, Henrik; Oide, Hideyuki; Okamura, Wataru; Okawa, Hideki; Okumura, Yasuyuki; Okuyama, Toyonobu; Olariu, Albert; Olivares Pino, Sebastian Andres; Oliveira Damazio, Denis; Oliver Garcia, Elena; Olszewski, Andrzej; Olszowska, Jolanta; Onofre, António; Onyisi, Peter; Oram, Christopher; Oreglia, Mark; Oren, Yona; Orestano, Domizia; Orlando, Nicola; Oropeza Barrera, Cristina; Orr, Robert; Osculati, Bianca; Ospanov, Rustem; Otero y Garzon, Gustavo; Otono, Hidetoshi; Ouchrif, Mohamed; Ouellette, Eric; Ould-Saada, Farid; Ouraou, Ahmimed; Oussoren, Koen Pieter; Ouyang, Qun; Ovcharova, Ana; Owen, Mark; Owen, Rhys Edward; Ozcan, Veysi Erkcan; Ozturk, Nurcan; Pachal, Katherine; Pacheco Pages, Andres; Padilla Aranda, Cristobal; Pagáčová, Martina; Pagan Griso, Simone; Paganis, Efstathios; Pahl, Christoph; Paige, Frank; Pais, Preema; Pajchel, Katarina; Palacino, Gabriel; Palestini, Sandro; Palka, Marek; Pallin, Dominique; Palma, Alberto; Pan, Yibin; Panagiotopoulou, Evgenia; Pandini, Carlo Enrico; Panduro Vazquez, William; Pani, Priscilla; Panitkin, Sergey; Pantea, Dan; Paolozzi, Lorenzo; Papadopoulou, Theodora; Papageorgiou, Konstantinos; Paramonov, Alexander; Paredes Hernandez, Daniela; Parker, Michael Andrew; Parker, Kerry Ann; Parodi, Fabrizio; Parsons, John; Parzefall, Ulrich; Pasqualucci, Enrico; Passaggio, Stefano; Pastore, Fernanda; Pastore, Francesca; Pásztor, Gabriella; Pataraia, Sophio; Patel, Nikhul; Pater, Joleen; Pauly, Thilo; Pearce, James; Pearson, Benjamin; Pedersen, Lars Egholm; Pedersen, Maiken; Pedraza Lopez, Sebastian; Pedro, Rute; Peleganchuk, Sergey; Pelikan, Daniel; Peng, Haiping; Penning, Bjoern; Penwell, John; Perepelitsa, Dennis; Perez Codina, Estel; Pérez García-Estañ, María Teresa; Perini, Laura; Pernegger, Heinz; Perrella, Sabrina; Peschke, Richard; Peshekhonov, Vladimir; Peters, Krisztian; Peters, Yvonne; Petersen, Brian; Petersen, Troels; Petit, Elisabeth; Petridis, Andreas; Petridou, Chariclia; Petrolo, Emilio; Petrucci, Fabrizio; Pettersson, Nora Emilia; Pezoa, Raquel; Phillips, Peter William; Piacquadio, Giacinto; Pianori, Elisabetta; Picazio, Attilio; Piccaro, Elisa; Piccinini, Maurizio; Pickering, Mark Andrew; Piegaia, Ricardo; Pignotti, David; Pilcher, James; Pilkington, Andrew; Pina, João Antonio; Pinamonti, Michele; Pinfold, James; Pingel, Almut; Pinto, Belmiro; Pires, Sylvestre; Pitt, Michael; Pizio, Caterina; Plazak, Lukas; Pleier, Marc-Andre; Pleskot, Vojtech; Plotnikova, Elena; Plucinski, Pawel; Pluth, Daniel; Poettgen, Ruth; Poggioli, Luc; Pohl, David-leon; Polesello, Giacomo; Policicchio, Antonio; Polifka, Richard; Polini, Alessandro; Pollard, Christopher Samuel; Polychronakos, Venetios; Pommès, Kathy; Pontecorvo, Ludovico; Pope, Bernard; Popeneciu, Gabriel Alexandru; Popovic, Dragan; Poppleton, Alan; Pospisil, Stanislav; Potamianos, Karolos; Potrap, Igor; Potter, Christina; Potter, Christopher; Poulard, Gilbert; Poveda, Joaquin; Pozdnyakov, Valery; Pralavorio, Pascal; Pranko, Aliaksandr; Prasad, Srivas; Prell, Soeren; Price, Darren; Price, Lawrence; Primavera, Margherita; Prince, Sebastien; Proissl, Manuel; Prokofiev, Kirill; Prokoshin, Fedor; Protopapadaki, Eftychia-sofia; Protopopescu, Serban; Proudfoot, James; Przybycien, Mariusz; Ptacek, Elizabeth; Puddu, Daniele; Pueschel, Elisa; Puldon, David; Purohit, Milind; Puzo, Patrick; Qian, Jianming; Qin, Gang; Qin, Yang; Quadt, Arnulf; Quarrie, David; Quayle, William; Queitsch-Maitland, Michaela; Quilty, Donnchadha; Raddum, Silje; Radeka, Veljko; Radescu, Voica; Radhakrishnan, Sooraj Krishnan; Radloff, Peter; Rados, Pere; Ragusa, Francesco; Rahal, Ghita; Rajagopalan, Srinivasan; Rammensee, Michael; Rangel-Smith, Camila; Rauscher, Felix; Rave, Stefan; Ravenscroft, Thomas; Raymond, Michel; Read, Alexander Lincoln; Readioff, Nathan Peter; Rebuzzi, Daniela; Redelbach, Andreas; Redlinger, George; Reece, Ryan; Reeves, Kendall; Rehnisch, Laura; Reisin, Hernan; Relich, Matthew; Rembser, Christoph; Ren, Huan; Renaud, Adrien; Rescigno, Marco; Resconi, Silvia; Rezanova, Olga; Reznicek, Pavel; Rezvani, Reyhaneh; Richter, Robert; Richter, Stefan; Richter-Was, Elzbieta; Ricken, Oliver; Ridel, Melissa; Rieck, Patrick; Riegel, Christian Johann; Rieger, Julia; Rijssenbeek, Michael; Rimoldi, Adele; Rinaldi, Lorenzo; Ristić, Branislav; Ritsch, Elmar; Riu, Imma; Rizatdinova, Flera; Rizvi, Eram; Robertson, Steven; Robichaud-Veronneau, Andree; Robinson, Dave; Robinson, James; Robson, Aidan; Roda, Chiara; Roe, Shaun; Røhne, Ole; Rolli, Simona; Romaniouk, Anatoli; Romano, Marino; Romano Saez, Silvestre Marino; Romero Adam, Elena; Rompotis, Nikolaos; Ronzani, Manfredi; Roos, Lydia; Ros, Eduardo; Rosati, Stefano; Rosbach, Kilian; Rose, Peyton; Rosendahl, Peter Lundgaard; Rosenthal, Oliver; Rossetti, Valerio; Rossi, Elvira; Rossi, Leonardo Paolo; Rosten, Rachel; Rotaru, Marina; Roth, Itamar; Rothberg, Joseph; Rousseau, David; Royon, Christophe; Rozanov, Alexandre; Rozen, Yoram; Ruan, Xifeng; Rubbo, Francesco; Rubinskiy, Igor; Rud, Viacheslav; Rudolph, Christian; Rudolph, Matthew Scott; Rühr, Frederik; Ruiz-Martinez, Aranzazu; Rurikova, Zuzana; Rusakovich, Nikolai; Ruschke, Alexander; Russell, Heather; Rutherfoord, John; Ruthmann, Nils; Ryabov, Yury; Rybar, Martin; Rybkin, Grigori; Ryder, Nick; Saavedra, Aldo; Sabato, Gabriele; Sacerdoti, Sabrina; Saddique, Asif; Sadrozinski, Hartmut; Sadykov, Renat; Safai Tehrani, Francesco; Saimpert, Matthias; Sakamoto, Hiroshi; Sakurai, Yuki; Salamanna, Giuseppe; Salamon, Andrea; Saleem, Muhammad; Salek, David; Sales De Bruin, Pedro Henrique; Salihagic, Denis; Salnikov, Andrei; Salt, José; Salvatore, Daniela; Salvatore, Pasquale Fabrizio; Salvucci, Antonio; Salzburger, Andreas; Sampsonidis, Dimitrios; Sanchez, Arturo; Sánchez, Javier; Sanchez Martinez, Victoria; Sandaker, Heidi; Sandbach, Ruth Laura; Sander, Heinz Georg; Sanders, Michiel; Sandhoff, Marisa; Sandoval, Carlos; Sandstroem, Rikard; Sankey, Dave; Sannino, Mario; Sansoni, Andrea; Santoni, Claudio; Santonico, Rinaldo; Santos, Helena; Santoyo Castillo, Itzebelt; Sapp, Kevin; Sapronov, Andrey; Saraiva, João; Sarrazin, Bjorn; Sasaki, Osamu; Sasaki, Yuichi; Sato, Koji; Sauvage, Gilles; Sauvan, Emmanuel; Savage, Graham; Savard, Pierre; Sawyer, Craig; Sawyer, Lee; Saxon, James; Sbarra, Carla; Sbrizzi, Antonio; Scanlon, Tim; Scannicchio, Diana; Scarcella, Mark; Scarfone, Valerio; Schaarschmidt, Jana; Schacht, Peter; Schaefer, Douglas; Schaefer, Ralph; Schaeffer, Jan; Schaepe, Steffen; Schaetzel, Sebastian; Schäfer, Uli; Schaffer, Arthur; Schaile, Dorothee; Schamberger, R.Dean; Scharf, Veit; Schegelsky, Valery; Scheirich, Daniel; Schernau, Michael; Schiavi, Carlo; Schillo, Christian; Schioppa, Marco; Schlenker, Stefan; Schmidt, Evelyn; Schmieden, Kristof; Schmitt, Christian; Schmitt, Sebastian; Schmitt, Stefan; Schneider, Basil; Schnellbach, Yan Jie; Schnoor, Ulrike; Schoeffel, Laurent; Schoening, Andre; Schoenrock, Bradley Daniel; Schopf, Elisabeth; Schorlemmer, Andre Lukas; Schott, Matthias; Schouten, Doug; Schovancova, Jaroslava; Schramm, Steven; Schreyer, Manuel; Schroeder, Christian; Schuh, Natascha; Schultens, Martin Johannes; Schultz-Coulon, Hans-Christian; Schulz, Holger; Schumacher, Markus; Schumm, Bruce; Schune, Philippe; Schwanenberger, Christian; Schwartzman, Ariel; Schwarz, Thomas Andrew; Schwegler, Philipp; Schwemling, Philippe; Schwienhorst, Reinhard; Schwindling, Jerome; Schwindt, Thomas; Schwoerer, Maud; Sciacca, Gianfranco; Scifo, Estelle; Sciolla, Gabriella; Scuri, Fabrizio; Scutti, Federico; Searcy, Jacob; Sedov, George; Sedykh, Evgeny; Seema, Pienpen; Seidel, Sally; Seiden, Abraham; Seifert, Frank; Seixas, José; Sekhniaidze, Givi; Sekhon, Karishma; Sekula, Stephen; Selbach, Karoline Elfriede; Seliverstov, Dmitry; Semprini-Cesari, Nicola; Serfon, Cedric; Serin, Laurent; Serkin, Leonid; Serre, Thomas; Sessa, Marco; Seuster, Rolf; Severini, Horst; Sfiligoj, Tina; Sforza, Federico; Sfyrla, Anna; Shabalina, Elizaveta; Shamim, Mansoora; Shan, Lianyou; Shang, Ruo-yu; Shank, James; Shapiro, Marjorie; Shatalov, Pavel; Shaw, Kate; Shaw, Savanna Marie; Shcherbakova, Anna; Shehu, Ciwake Yusufu; Sherwood, Peter; Shi, Liaoshan; Shimizu, Shima; Shimmin, Chase Owen; Shimojima, Makoto; Shiyakova, Mariya; Shmeleva, Alevtina; Shoaleh Saadi, Diane; Shochet, Mel; Shojaii, Seyedruhollah; Shrestha, Suyog; Shulga, Evgeny; Shupe, Michael; Shushkevich, Stanislav; Sicho, Petr; Sidiropoulou, Ourania; Sidorov, Dmitri; Sidoti, Antonio; Siegert, Frank; Sijacki, Djordje; Silva, José; Silver, Yiftah; Silverstein, Samuel; Simak, Vladislav; Simard, Olivier; Simic, Ljiljana; Simion, Stefan; Simioni, Eduard; Simmons, Brinick; Simon, Dorian; Simoniello, Rosa; Sinervo, Pekka; Sinev, Nikolai; Siragusa, Giovanni; Sisakyan, Alexei; Sivoklokov, Serguei; Sjölin, Jörgen; Sjursen, Therese; Skinner, Malcolm Bruce; Skottowe, Hugh Philip; Skubic, Patrick; Slater, Mark; Slavicek, Tomas; Slawinska, Magdalena; Sliwa, Krzysztof; Smakhtin, Vladimir; Smart, Ben; Smestad, Lillian; Smirnov, Sergei; Smirnov, Yury; Smirnova, Lidia; Smirnova, Oxana; Smith, Matthew; Smizanska, Maria; Smolek, Karel; Snesarev, Andrei; Snidero, Giacomo; Snyder, Scott; Sobie, Randall; Socher, Felix; Soffer, Abner; Soh, Dart-yin; Solans, Carlos; Solar, Michael; Solc, Jaroslav; Soldatov, Evgeny; Soldevila, Urmila; Solodkov, Alexander; Soloshenko, Alexei; Solovyanov, Oleg; Solovyev, Victor; Sommer, Philip; Song, Hong Ye; Soni, Nitesh; Sood, Alexander; Sopczak, Andre; Sopko, Bruno; Sopko, Vit; Sorin, Veronica; Sosa, David; Sosebee, Mark; Sotiropoulou, Calliope Louisa; Soualah, Rachik; Soueid, Paul; Soukharev, Andrey; South, David; Spagnolo, Stefania; Spalla, Margherita; Spanò, Francesco; Spearman, William Robert; Spettel, Fabian; Spighi, Roberto; Spigo, Giancarlo; Spiller, Laurence Anthony; Spousta, Martin; Spreitzer, Teresa; St Denis, Richard Dante; Staerz, Steffen; Stahlman, Jonathan; Stamen, Rainer; Stamm, Soren; Stanecka, Ewa; Stanescu, Cristian; Stanescu-Bellu, Madalina; Stanitzki, Marcel Michael; Stapnes, Steinar; Starchenko, Evgeny; Stark, Jan; Staroba, Pavel; Starovoitov, Pavel; Staszewski, Rafal; Stavina, Pavel; Steinberg, Peter; Stelzer, Bernd; Stelzer, Harald Joerg; Stelzer-Chilton, Oliver; Stenzel, Hasko; Stern, Sebastian; Stewart, Graeme; Stillings, Jan Andre; Stockton, Mark; Stoebe, Michael; Stoicea, Gabriel; Stolte, Philipp; Stonjek, Stefan; Stradling, Alden; Straessner, Arno; Stramaglia, Maria Elena; Strandberg, Jonas; Strandberg, Sara; Strandlie, Are; Strauss, Emanuel; Strauss, Michael; Strizenec, Pavol; Ströhmer, Raimund; Strom, David; Stroynowski, Ryszard; Strubig, Antonia; Stucci, Stefania Antonia; Stugu, Bjarne; Styles, Nicholas Adam; Su, Dong; Su, Jun; Subramaniam, Rajivalochan; Succurro, Antonella; Sugaya, Yorihito; Suhr, Chad; Suk, Michal; Sulin, Vladimir; Sultansoy, Saleh; Sumida, Toshi; Sun, Siyuan; Sun, Xiaohu; Sundermann, Jan Erik; Suruliz, Kerim; Susinno, Giancarlo; Sutton, Mark; Suzuki, Shota; Suzuki, Yu; Svatos, Michal; Swedish, Stephen; Swiatlowski, Maximilian; Sykora, Ivan; Sykora, Tomas; Ta, Duc; Taccini, Cecilia; Tackmann, Kerstin; Taenzer, Joe; Taffard, Anyes; Tafirout, Reda; Taiblum, Nimrod; Takai, Helio; Takashima, Ryuichi; Takeda, Hiroshi; Takeshita, Tohru; Takubo, Yosuke; Talby, Mossadek; Talyshev, Alexey; Tam, Jason; Tan, Kong Guan; Tanaka, Junichi; Tanaka, Reisaburo; Tanaka, Satoshi; Tanaka, Shuji; Tannenwald, Benjamin Bordy; Tannoury, Nancy; Tapprogge, Stefan; Tarem, Shlomit; Tarrade, Fabien; Tartarelli, Giuseppe Francesco; Tas, Petr; Tasevsky, Marek; Tashiro, Takuya; Tassi, Enrico; Tavares Delgado, Ademar; Tayalati, Yahya; Taylor, Frank; Taylor, Geoffrey; Taylor, Wendy; Teischinger, Florian Alfred; Teixeira Dias Castanheira, Matilde; Teixeira-Dias, Pedro; Temming, Kim Katrin; Ten Kate, Herman; Teng, Ping-Kun; Teoh, Jia Jian; Tepel, Fabian-Phillipp; Terada, Susumu; Terashi, Koji; Terron, Juan; Terzo, Stefano; Testa, Marianna; Teuscher, Richard; Therhaag, Jan; Theveneaux-Pelzer, Timothée; Thomas, Juergen; Thomas-Wilsker, Joshuha; Thompson, Emily; Thompson, Paul; Thompson, Ray; Thompson, Stan; Thomsen, Lotte Ansgaard; Thomson, Evelyn; Thomson, Mark; Thun, Rudolf; Tibbetts, Mark James; Ticse Torres, Royer Edson; Tikhomirov, Vladimir; Tikhonov, Yury; Timoshenko, Sergey; Tiouchichine, Elodie; Tipton, Paul; Tisserant, Sylvain; Todorov, Theodore; Todorova-Nova, Sharka; Tojo, Junji; Tokár, Stanislav; Tokushuku, Katsuo; Tollefson, Kirsten; Tolley, Emma; Tomlinson, Lee; Tomoto, Makoto; Tompkins, Lauren; Toms, Konstantin; Torrence, Eric; Torres, Heberth; Torró Pastor, Emma; Toth, Jozsef; Touchard, Francois; Tovey, Daniel; Trefzger, Thomas; Tremblet, Louis; Tricoli, Alessandro; Trigger, Isabel Marian; Trincaz-Duvoid, Sophie; Tripiana, Martin; Trischuk, William; Trocmé, Benjamin; Troncon, Clara; Trottier-McDonald, Michel; Trovatelli, Monica; True, Patrick; Truong, Loan; Trzebinski, Maciej; Trzupek, Adam; Tsarouchas, Charilaos; Tseng, Jeffrey; Tsiareshka, Pavel; Tsionou, Dimitra; Tsipolitis, Georgios; Tsirintanis, Nikolaos; Tsiskaridze, Shota; Tsiskaridze, Vakhtang; Tskhadadze, Edisher; Tsukerman, Ilya; Tsulaia, Vakhtang; Tsuno, Soshi; Tsybychev, Dmitri; Tudorache, Alexandra; Tudorache, Valentina; Tuna, Alexander Naip; Tupputi, Salvatore; Turchikhin, Semen; Turecek, Daniel; Turra, Ruggero; Turvey, Andrew John; Tuts, Michael; Tykhonov, Andrii; Tylmad, Maja; Tyndel, Mike; Ueda, Ikuo; Ueno, Ryuichi; Ughetto, Michael; Ugland, Maren; Uhlenbrock, Mathias; Ukegawa, Fumihiko; Unal, Guillaume; Undrus, Alexander; Unel, Gokhan; Ungaro, Francesca; Unno, Yoshinobu; Unverdorben, Christopher; Urban, Jozef; Urquijo, Phillip; Urrejola, Pedro; Usai, Giulio; Usanova, Anna; Vacavant, Laurent; Vacek, Vaclav; Vachon, Brigitte; Valderanis, Chrysostomos; Valencic, Nika; Valentinetti, Sara; Valero, Alberto; Valery, Loic; Valkar, Stefan; Valladolid Gallego, Eva; Vallecorsa, Sofia; Valls Ferrer, Juan Antonio; Van Den Wollenberg, Wouter; Van Der Deijl, Pieter; van der Geer, Rogier; van der Graaf, Harry; Van Der Leeuw, Robin; van Eldik, Niels; van Gemmeren, Peter; Van Nieuwkoop, Jacobus; van Vulpen, Ivo; van Woerden, Marius Cornelis; Vanadia, Marco; Vandelli, Wainer; Vanguri, Rami; Vaniachine, Alexandre; Vannucci, Francois; Vardanyan, Gagik; Vari, Riccardo; Varnes, Erich; Varol, Tulin; Varouchas, Dimitris; Vartapetian, Armen; Varvell, Kevin; Vazeille, Francois; Vazquez Schroeder, Tamara; Veatch, Jason; Veloso, Filipe; Velz, Thomas; 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Wang, Chao; Wang, Fuquan; Wang, Haichen; Wang, Hulin; Wang, Jike; Wang, Jin; Wang, Kuhan; Wang, Rui; Wang, Song-Ming; Wang, Tan; Wang, Xiaoxiao; Wanotayaroj, Chaowaroj; Warburton, Andreas; Ward, Patricia; Wardrope, David Robert; Warsinsky, Markus; Washbrook, Andrew; Wasicki, Christoph; Watkins, Peter; Watson, Alan; Watson, Ian; Watson, Miriam; Watts, Gordon; Watts, Stephen; Waugh, Ben; Webb, Samuel; Weber, Michele; Weber, Stefan Wolf; Webster, Jordan S; Weidberg, Anthony; Weinert, Benjamin; Weingarten, Jens; Weiser, Christian; Weits, Hartger; Wells, Phillippa; Wenaus, Torre; Wengler, Thorsten; Wenig, Siegfried; Wermes, Norbert; Werner, Matthias; Werner, Per; Wessels, Martin; Wetter, Jeffrey; Whalen, Kathleen; Wharton, Andrew Mark; White, Andrew; White, Martin; White, Ryan; White, Sebastian; Whiteson, Daniel; Wickens, Fred; Wiedenmann, Werner; Wielers, Monika; Wienemann, Peter; Wiglesworth, Craig; Wiik-Fuchs, Liv Antje Mari; Wildauer, Andreas; Wilkens, Henric George; Williams, Hugh; Williams, Sarah; Willis, Christopher; Willocq, Stephane; Wilson, Alan; Wilson, John; Wingerter-Seez, Isabelle; Winklmeier, Frank; Winter, Benedict Tobias; Wittgen, Matthias; Wittkowski, Josephine; Wollstadt, Simon Jakob; Wolter, Marcin Wladyslaw; Wolters, Helmut; Wosiek, Barbara; Wotschack, Jorg; Woudstra, Martin; Wozniak, Krzysztof; Wu, Mengqing; Wu, Miles; Wu, Sau Lan; Wu, Xin; Wu, Yusheng; Wyatt, Terry Richard; Wynne, Benjamin; Xella, Stefania; Xu, Da; Xu, Lailin; Yabsley, Bruce; Yacoob, Sahal; Yakabe, Ryota; Yamada, Miho; Yamaguchi, Yohei; Yamamoto, Akira; Yamamoto, Shimpei; Yamanaka, Takashi; Yamauchi, Katsuya; Yamazaki, Yuji; Yan, Zhen; Yang, Haijun; Yang, Hongtao; Yang, Yi; Yao, Liwen; Yao, Weiming; Yasu, Yoshiji; Yatsenko, Elena; Yau Wong, Kaven Henry; Ye, Jingbo; Ye, Shuwei; Yeletskikh, Ivan; Yen, Andy L; Yildirim, Eda; Yorita, Kohei; Yoshida, Rikutaro; Yoshihara, Keisuke; Young, Charles; Young, Christopher John; Youssef, Saul; Yu, David Ren-Hwa; Yu, Jaehoon; Yu, Jiaming; Yu, Jie; Yuan, Li; Yurkewicz, Adam; Yusuff, Imran; Zabinski, Bartlomiej; Zaidan, Remi; Zaitsev, Alexander; Zalieckas, Justas; Zaman, Aungshuman; Zambito, Stefano; Zanello, Lucia; Zanzi, Daniele; Zeitnitz, Christian; Zeman, Martin; Zemla, Andrzej; Zengel, Keith; Zenin, Oleg; Ženiš, Tibor; Zerwas, Dirk; Zhang, Dongliang; Zhang, Fangzhou; Zhang, Jinlong; Zhang, Lei; Zhang, Ruiqi; Zhang, Xueyao; Zhang, Zhiqing; Zhao, Xiandong; Zhao, Yongke; Zhao, Zhengguo; Zhemchugov, Alexey; Zhong, Jiahang; Zhou, Bing; Zhou, Chen; Zhou, Lei; Zhou, Li; Zhou, Ning; Zhu, Cheng Guang; Zhu, Hongbo; Zhu, Junjie; Zhu, Yingchun; Zhuang, Xuai; Zhukov, Konstantin; Zibell, Andre; Zieminska, Daria; Zimine, Nikolai; Zimmermann, Christoph; Zimmermann, Stephanie; Zinonos, Zinonas; Zinser, Markus; Ziolkowski, Michael; Živković, Lidija; Zobernig, Georg; Zoccoli, Antonio; zur Nedden, Martin; Zurzolo, Giovanni; Zwalinski, Lukasz

    2015-08-08

    A search for heavy long-lived multi-charged particles is performed using the ATLAS detector at the LHC. Data collected in 2012 at $\\sqrt{s}$=8 TeV from $pp$ collisions corresponding to an integrated luminosity of $20.3$ fb$^{-1}$ are examined. Particles producing anomalously high ionisation, consistent with long-lived massive particles with electric charges from $|q|=2e$ to $|q|=6e$ are searched for. No signal candidate events are observed, and 95% confidence level cross-section upper limits are interpreted as lower mass limits for a Drell--Yan production model. The mass limits range between 660 and 785 GeV.

  19. Heavy-ion radiography

    International Nuclear Information System (INIS)

    Fabrikant, J.I.; Tobias, C.A.; Holley, W.R.; Benton, E.V.; Woodruff, K.H.; MacFarland, E.W.

    1983-01-01

    High energy, heavy-ion beams offer superior discrimination of tissue electron densities at very low radiation doses. This characteristic has potential for diagnostic medical imaging of neoplasms arising in the soft tissues and organs because it can detect smaller inhomogeneities than x rays. Heavy-ion imaging may also increase the accuracy of cancer radiotherapy planning involving use of accelerated charged particles. In the current physics research program of passive heavy-ion imaging, critical modulation transfer function tests are being carried out in heavy-ion projection radiography and heavy-ion computerized tomography. The research goal is to improve the heavy-ion imaging method until it reaches the limits of its theoretical resolution defined by range straggling, multiple scattering, and other factors involved in the beam quality characteristics. Clinical uses of the imaging method include the application of heavy-ion computerized tomography to heavy-ion radiotherapy planning, to the study of brain tumors and other structures of the head, and to low-dose heavy-ion projection mammography, particularly for women with dense breasts where other methods of diagnosis fail. The ions used are primarily 300 to 570 MeV/amu carbon and neon ions accelerated at the Lawrence Berkeley Laboratory Bevalac

  20. Time-response characteristic and potential biomarker identification of heavy metal induced toxicity in zebrafish.

    Science.gov (United States)

    Yin, Jian; Wang, Ai-Ping; Li, Wan-Fang; Shi, Rui; Jin, Hong-Tao; Wei, Jin-Feng

    2018-01-01

    The present work aims to explore the time-response (from 24 h to 96 h) characteristic and identify early potential sensitive biomarkers of copper (Cu) (as copper chloride dihydrate), cadmium (Cd) (as cadmium acetate), lead (Pb) (as lead nitrate) and chromium (Cr) (as potassium dichromate) exposure in adult zebrafish, focusing on reactive oxygen species (ROS), SOD activity, lipid peroxidation and gene expression related to oxidative stress and inflammatory response. Furthermore, the survival rate decreased apparently by a concentration-dependent manner after Cu, Cr, Cd and Pb exposure, and we selected non-lethal concentrations 0.05 mg/L for Cu, 15 mg/L for Cr, 3 mg/L for Cd and 93.75μg/L for Pb to test the effect on the following biological indicators. Under non-lethal concentration, the four heavy metals have no apparent histological change in adult zebrafish gills. Similar trends in ROS production, MDA level and SOD activity were up-regulated by the four heavy metals, while MDA level responded more sensitive to Pb by time-dependent manner than the other three heavy metals. In addition, mRNA levels related to antioxidant system (SOD1, SOD2 and Nrf2) were up-regulated by non-lethal concentration Cu, Cr, Cd and Pb exposure. MDA level and SOD1 gene have a more delayed response to heavy metals. Genes related to immunotoxicity were increased significantly after heavy metals exposure at non-lethal concentrations. TNF-α and IL-1β gene have similar sensibility to the four heavy metals, while IL-8 gene was more responsive to Cr, Cd and Pb exposure at 48 h groups and IFN-γ gene showed more sensitivity to Cu at 48 h groups than the other heavy metals. In conclusion, the present works have suggested that the IFN-γ gene may applied as early sensitive biomarker to identify Cu-induced toxicity, while MDA content and IL-8 gene may use as early sensitive biomarkers for evaluating the risk of Pb exposure. Moreover, IL-8 and IFN-γ gene were more responsive to heavy

  1. Dual neutral particle induced transmutation in CINDER2008

    Energy Technology Data Exchange (ETDEWEB)

    Martin, W.J., E-mail: wjmarti@sandia.gov [Sandia National Laboratories, Albuquerque, NM 87185 (United States); University of New Mexico, Albuquerque, NM 87131 (United States); Oliveira, C.R.E. de; Hecht, A.A. [University of New Mexico, Albuquerque, NM 87131 (United States)

    2014-12-11

    Although nuclear transmutation methods for fission have existed for decades, the focus has been on neutron-induced reactions. Recent novel concepts have sought to use both neutrons and photons for purposes such as active interrogation of cargo to detect the smuggling of highly enriched uranium, a concept that would require modeling the transmutation caused by both incident particles. As photonuclear transmutation has yet to be modeled alongside neutron-induced transmutation in a production code, new methods need to be developed. The CINDER2008 nuclear transmutation code from Los Alamos National Laboratory is extended from neutron applications to dual neutral particle applications, allowing both neutron- and photon-induced reactions for this modeling with a focus on fission. Following standard reaction modeling, the induced fission reaction is understood as a two-part reaction, with an entrance channel to the excited compound nucleus, and an exit channel from the excited compound nucleus to the fission fragmentation. Because photofission yield data—the exit channel from the compound nucleus—are sparse, neutron fission yield data are used in this work. With a different compound nucleus and excitation, the translation to the excited compound state is modified, as appropriate. A verification and validation of these methods and data has been performed. This has shown that the translation of neutron-induced fission product yield sets, and their use in photonuclear applications, is appropriate, and that the code has been extended correctly. - Highlights: • The CINDER2008 transmutation code was modified to include photon-induced transmutation tracking. • A photonuclear interaction library was created to allow CINDER2008 to track photonuclear interactions. • Photofission product yield data sets were created using fission physics similarities with neutron-induced fission.

  2. Heavy Ion Microbeam- and Broadbeam-Induced Transients in SiGe HBTs

    Science.gov (United States)

    Pellish, Jonathan A.; Reed, Robert A.; McMorrow, Dale; Vizkelethy, Gyorgy; Ferlet-Cavrois, Veronique; Baggio, Jacques; Duhamel, Olivier; Moen, Kurt A.; Phillips, Stanley D.; Diestelhorst, Ryan M.; hide

    2009-01-01

    SiGe HBT heavy ion-induced current transients are measured using Sandia National Laboratories microbeam and high- and low-energy broadbeam sources at the Grand Accelerateur National d'Ions Lourds and the University of Jyvaskyla. The data were captured using a custom broadband IC package and real-time digital phosphor oscilloscopes with at least 16 GHz of analog bandwidth. These data provide detailed insight into the effects of ion strike location, range, and LET.

  3. Study of α-particle multiplicity in 16O+196Pt fusion-fission reaction

    International Nuclear Information System (INIS)

    Kapoor, K.; Kumar, A.; Bansal, N.

    2016-01-01

    Study of dynamics of fusion-fission reaction is one of the interesting parts of heavy-ion-induced nuclear reaction. Extraction of fission time scales using different probes is of central importance for understanding the dynamics of fusion-fission process. In the past, extensive theoretical and experimental efforts have been made to understand the various aspects of the heavy ion induced fusion-fission reactions. Compelling evidences have been obtained from the earlier studies that the fission decay of hot nuclei is protracted process i.e. slowed down relative to the expectations of the standard statistical model, and large dynamical delays are required due to this hindrance. Nuclear dissipation is assumed to be responsible for this delay and more light particles are expected to be emitted during the fission process. One of neutron multiplicity measurements have been performed for the 16,18 O+ 194,198 Pt populating the CN 210,212,214,216 Rn and observed fission delay due to nuclear viscosity. In order to have complete understanding for the dynamics of 212 Rn nucleus, we measured the charged particle multiplicity for 16 O+ 196 Pt system. Study of charged particles will give us more information about the emitter in comparison to neutrons as charged particles faces Coulomb barrier and are more sensitive probe for understanding the dynamics of fusion-fission reactions. In the present work, we are reporting some of the preliminary results of charged particle multiplicity

  4. Review of Particle Physics, 2012-2013

    CERN Document Server

    Beringer, J; Barnett, R M; Copic, K; Dahl, O; Groom, D E; Lin, C J; Lys, J; Murayama, H; Wohl, C G; Yao, W M; Zyla, P A; Amsler, C; Antonelli, M; Asner, D M; Baer, H; Band, H R; Basaglia, T; Bauer, C W; Beatty, J J; Belousov, V I; Bergren, E; Bernardi, G; Bertl, W; Bethke, S; Bichsel, H; Biebel, O; Blucher, E; Blusk, S; Brooijmans, G; Buchmueller, O; Cahn, R N; Carena, M; Ceccucci, A; Chakraborty, D; Chen, M C; Chivukula, R S; Cowan, G; D'Ambrosio, G; Damour, T; de Florian, D; de Gouvea, A; DeGrand, T; de Jong, P; Dissertori, G; Dobrescu, B; Doser, M; Drees, M; Edwards, D A; Eidelman, S; Erler, J; Ezhela, V V; Fetscher, W; Fields, B D; Foster, B; Gaisser, T K; Garren, L; Gerber, H J; Gerbier, G; Gherghetta, T; Golwala, S; Goodman, M; Grab, C; Gritsan, A V; Grivaz, J F; Grunewald, M; Gurtu, A; Gutsche, T; Haber, H E; Hagiwara, K; Hagmann, C; Hanhart, C; Hashimoto, S; Hayes, K G; Heffner, M; Heltsley, B; Hernandez-Rey, J J; Hikasa, K; Hocker, A; Holder, J; Holtkamp, A; Huston, J; Jackson, J D; Johnson, K F; Junk, T; Karlen, D; Kirkby, D; Klein, S R; Klempt, E; Kowalewski, R V; Krauss, F; Kreps, M; Krusche, B; Kuyanov, Yu.V; Kwon, Y; Lahav, O; Laiho, J; Langacker, P; Liddle, A; Ligeti, Z; Liss, T M; Littenberg, L; Lugovsky, K S; Lugovsky, S B; Mannel, T; Manohar, A V; Marciano, W J; Martin, A D; Masoni, A; Matthews, J; Milstead, D; Miquel, R; Monig, K; Moortgat, F; Nakamura, K; Narain, M; Nason, P; Navas, S; Neubert, M; Nevski, P; Nir, Y; Olive, K A; Pape, L; Parsons, J; Patrignani, C; Peacock, J A; Petcov, S T; Piepke, A; Pomarol, A; Punzi, G; Quadt, A; Raby, S; Raffelt, G; Ratcliff, B N; Richardson, P; Roesler, S; Rolli, S; Romaniouk, A; Rosenberg, L J; Rosner, J L; Sachrajda, C T; Sakai, Y; Salam, G P; Sarkar, S; Sauli, F; Schneider, O; Scholberg, K; Scott, D; Seligman, W G; Shaevitz, M H; Sharpe, S R; Silari, M; Sjostrand, T; Skands, P; Smith, J G; Smoot, G F; Spanier, S; Spieler, H; Stahl, A; Stanev, T; Stone, S L; Sumiyoshi, T; Syphers, M J; Takahashi, F; Tanabashi, M; Terning, J; Titov, M; Tkachenko, N P; Tornqvist, N A; Tovey, D; Valencia, G; van Bibber, K; Venanzoni, G; Vincter, M G; Vogel, P; Vogt, A; Walkowiak, W; Walter, C W; Ward, D R; Watari, T; Weiglein, G; Weinberg, E J; Wiencke, L R; Wolfenstein, L; Womersley, J; Woody, C L; Workman, R L; Yamamoto, A; Zeller, G P; Zenin, O V; Zhang, J; Zhu, R Y; Harper, G; Lugovsky, V S; Schaffner, P

    2012-01-01

    This biennial Review summarizes much of particle physics. Using data from previous editions, plus 2658 new measurements from 644 papers, we list, evaluate, and average measured properties of gauge bosons, leptons, quarks, mesons, and baryons. We summarize searches for hypothetical particles such as Higgs bosons, heavy neutrinos, and supersymmetric particles. All the particle properties and search limits are listed in Summary Tables. We also give numerous tables, figures, formulae, and reviews of topics such as the Standard Model, particle detectors, probability, and statistics. Among the 112 reviews are many that are new or heavily revised including those on Heavy-Quark and Soft-Collinear Effective Theory, Neutrino Cross Section Measurements, Monte Carlo Event Generators, Lattice QCD, Heavy Quarkonium Spectroscopy, Top Quark, Dark Matter, Vcb & Vub, Quantum Chromodynamics, High-Energy Collider Parameters, Astrophysical Constants, Cosmological Parameters, and Dark Matter.

  5. Intense heavy ion beam-induced effects in carbon-based stripper foils

    Energy Technology Data Exchange (ETDEWEB)

    Kupka, Katharina

    2016-08-15

    Amorphous carbon or carbon-based stripper foils are commonly applied in accelerator technology for electron stripping of ions. At the planned facility for antiproton and ion research (FAIR) at the Helmholtzzentrum fuer Schwerionenforschung (GSI), Darmstadt, thin carbon stripper foils provide an option for directly delivering ions of intermediate charge states to the heavy ion synchrotron, SIS 18, in order to mitigate space charge limitations during high-intensity operation. In case of desired high end-energies in the synchrotron, a second stripping process by a thicker carbon foil provides ions of higher charge states for injection into the SIS18. High beam intensities and a pulsed beam structure as foreseen at FAIR pose new challenges to the stripper foils which experience enhanced degradation by radiation damage, thermal effects, and stress waves. In order to ensure reliable accelerator operation, radiation-hard stripper foils are required. This thesis aims to a better understanding of processes leading to degradation of carbon-based thin foils. Special focus is placed on ion-beam induced structure and physical property changes and on the influence of different beam parameters. Irradiation experiments were performed at the M3-beamline of the universal linear accelerator (UNILAC) at GSI, using swift heavy ion beams with different pulse lengths and repetition rates. Tested carbon foils were standard amorphous carbon stripper foils produced by the GSI target laboratory, as well as commercial amorphous and diamond-like carbon foils and buckypaper foils. Microstructural changes were investigated with various methods such as optical microscopy, scanning electron microscopy (SEM), profilometry and chromatic aberration measurements. For the investigation of structural changes X-ray photoelectron spectroscopy (XPS), Raman spectroscopy, high resolution transmission electron microscopy (HRTEM), in-situ Fourier-transform infrared spectroscopy (FTIR) and small angle X

  6. Intense heavy ion beam-induced effects in carbon-based stripper foils

    International Nuclear Information System (INIS)

    Kupka, Katharina

    2016-08-01

    Amorphous carbon or carbon-based stripper foils are commonly applied in accelerator technology for electron stripping of ions. At the planned facility for antiproton and ion research (FAIR) at the Helmholtzzentrum fuer Schwerionenforschung (GSI), Darmstadt, thin carbon stripper foils provide an option for directly delivering ions of intermediate charge states to the heavy ion synchrotron, SIS 18, in order to mitigate space charge limitations during high-intensity operation. In case of desired high end-energies in the synchrotron, a second stripping process by a thicker carbon foil provides ions of higher charge states for injection into the SIS18. High beam intensities and a pulsed beam structure as foreseen at FAIR pose new challenges to the stripper foils which experience enhanced degradation by radiation damage, thermal effects, and stress waves. In order to ensure reliable accelerator operation, radiation-hard stripper foils are required. This thesis aims to a better understanding of processes leading to degradation of carbon-based thin foils. Special focus is placed on ion-beam induced structure and physical property changes and on the influence of different beam parameters. Irradiation experiments were performed at the M3-beamline of the universal linear accelerator (UNILAC) at GSI, using swift heavy ion beams with different pulse lengths and repetition rates. Tested carbon foils were standard amorphous carbon stripper foils produced by the GSI target laboratory, as well as commercial amorphous and diamond-like carbon foils and buckypaper foils. Microstructural changes were investigated with various methods such as optical microscopy, scanning electron microscopy (SEM), profilometry and chromatic aberration measurements. For the investigation of structural changes X-ray photoelectron spectroscopy (XPS), Raman spectroscopy, high resolution transmission electron microscopy (HRTEM), in-situ Fourier-transform infrared spectroscopy (FTIR) and small angle X

  7. Cement analysis by particle-induced prompt photon spectrometry: comparison of the effect of different charged particle beams

    International Nuclear Information System (INIS)

    Gihwala, D.; Peisach, M.

    1985-01-01

    Standard cements were analysed by particle-induced prompt photon spectrometry (PIPPS) using 4,75-MeV protons, 5-MeV 4 He+ ions, and 2-MeV deuterons. Precision and sensitivity attainable were compared. Protons and alpha-particles were comparable for the determination of F, Na, Mg and Si. Protons were preferred for P and Ca, and alpha-particles for the direct determination of O. Sources of interference are discussed with particular reference to delayed gamma-ray emission from deuteron bombardment

  8. The rotationally induced quadrupole pair field in the particle-rotor model

    International Nuclear Information System (INIS)

    Almberger, J.

    1980-04-01

    A formalism is developed which makes it possible to consider the influence of the rotationally induced quadrupole pair field and corresponding quasi-particle residual interactions within the particle-rotor model. The Y 21 pair field renormalizes both the Coriolis and the recoil interactions. (Auth.)

  9. Spin-selective depopulation of triplet sublevels in rapidly rotating triplet exciplexes detected by a heavy-atom-induced magnetic field effect

    OpenAIRE

    Steiner, Ulrich

    1980-01-01

    A mechanism is presented explaining a reported heavy-atom-induced magnetic field effect as a consequence of non-equilibrium triplet sublevel population in an intermediate exciplex. The triplet exciplex spin polarization is induced by sub-level-selective intersystem crossing from the exciplex triplet to its singlet ground state and is decreased by an external magnetic field. The theory accounts almost quantitatively for the observed influence of magnetic field strength and heavy-atom substitue...

  10. On the production of shower particles from light (Cno) and heavy (Ag Br) emulsion nuclei at Dubna energy

    International Nuclear Information System (INIS)

    EI-Nagdy, M.S.; Abdel-Waged, Kh; Abdel-Halim, S.M.; Khalil, E.I.

    2000-01-01

    The reaction cross sections for p, d, He, C, Mg and S beams with different chemical components of emulsion nuclei at 4.5 A GeV/c have been studied with high statistics, and were compared with the calculations according to Glauber model. The multiplicity distributions of shower produced particles from these interactions with light and heavy emulsion nuclei are analyzed in terms of the negative binomial and Poisson distribution laws

  11. Lifetimes of heavy flavour particles

    International Nuclear Information System (INIS)

    Forty, R.

    1994-01-01

    The lifetimes of heavy-flavour hadrons are reviewed. After a brief discussion of the theoretical predictions, the problem of averaging lifetime measurements is discussed. The various experimental measurements are then presented and suitable averages performed. Charmed meson lifetimes are now measured to the few percent level, better that theory can predict, whilst for charmed baryons the lifetime hierarchy has been established for the first time. For beauty hadrons the lifetimes are measured at the 6-10 % level, and are in reasonable agreement with theoretical expectations. Beauty baryon studies ar just beginning. (author)

  12. Behavioral effects of heavy ions and protons and potential countermeasure agents

    Science.gov (United States)

    Vazquez, M.; Gatley, J.; Bruneus, M.; Koslosky, S.; Billups, A.

    Space travel beyond the Earth's protective magnetic field (for example, to Mars) will involve exposure of astronauts to irradiation by high-energy nuclei such as 56 Fe, which are a component of galactic cosmic rays. These particles have high linear energy transfer (LET) and are expected to irreversibly damage cells they traverse. Exposure to HZE radiation may therefore cause progressive deterioration of brain function, adding to other inescapable damage involved in normal aging. We propose a study of the hypothesis that long-term behavioral alterations are induced after exposure of the brain to 1 GeV/n iron and silicon particles with fluences of 1 to 8 particles/cell targets. Previous studies support this notion but are not definitive, especially with regard to long-term effects. Our principal goal is to examine the neurological effects of high-LET radiation on C57BL/6 mice using a series of behavioral tests to unveil the temporal expression of altered behaviors in the radiation response, as well as the means, which can modulate these responses. The studies planned in this project are designed to: 1) Characterize the behavioral consequences after exposure to low-fluences of heavy ions and protons on C57BL/6 mice. The main behavioral endpoints to be used in these studies are locomotor activity to evaluate the integrity of striatal dopaminergic pathways, and spatial reference memory to probe hippocampal cholinergic pathways. 2) Characterize the neurochemical and structural changes induced by heavy ions and protons. 3) To develop countermeasures to protect neural cell populations exposed to low fluences of heavy ions and protons. The project will test methods to protect injured neural cells based on their molecular and cellular mechanisms that may regulate neural cell survival in the central nervous system. Among the methods that will be studied is the direct administration of neuroprotective molecules as well as the modulation of apoptotic pathways by pharmacological

  13. Heavy ion accelerators

    International Nuclear Information System (INIS)

    Schmelzer, C.

    1974-01-01

    This review of the present state of work on heavy-ion accelerators pays particular attention to the requirements for nuclear research. It is divided into the following sections: single-particle versus collective acceleration, heavy-ion accelerators, beam quality, and a status report on the UNILAC facility. Among the topics considered are the recycling cyclotron, linacs with superconducting resonators, and acceleration to the GeV/nucleon range. (8 figures, 2 tables) (U.S.)

  14. Occurrence and distribution of heavy metals in indoor settled ...

    African Journals Online (AJOL)

    The results showed widespread heavy metals contamination especially Fe and Zn, which were present as the highest concentration while Cd was the lowest in the settled particles (dust). The order of occurrence of heavy metals in settled particles (dust) collected indoor in 2007 and 2008 respectively were as follows, ...

  15. Heavy-Ion Collimation at the Large Hadron Collider: Simulations and Measurements

    OpenAIRE

    Hermes, Pascal Dominik; Wessels, Johannes Peter; Bruce, Roderik; Wessels, Johannes Peter; Bruce, Roderik

    2017-01-01

    The CERN Large Hadron Collider (LHC) stores and collides proton and $^{208}$Pb$^{82+}$ beams of unprecedented energy and intensity. Thousands of superconducting magnets, operated at 1.9 K, guide the very intense and energetic particle beams, which have a large potential for destruction. This implies the demand for a multi-stage collimation system to provide protection from beam-induced quenches or even hardware damage. In heavy-ion operation, ion fragments with significant rigidity offsets ca...

  16. Identified particle yield associated with a high-$p_T$ trigger particle at the LHC

    CERN Document Server

    Veldhoen, Misha; van Leeuwen, Marco

    Identified particle production ratios are important observables, used to constrain models of particle production in heavy-ion collisions. Measurements of the inclusive particle ratio in central heavy-ion collisions showed an increase of the baryon-to-meson ratio compared to proton-proton collisions at intermediate pT, the so-called baryon anomaly. One possible explanation of the baryon anomaly is that partons from the thermalized deconfined QCD matter hadronize in a different way compared to hadrons produced in a vacuum jet. In this work we extend on previous measurements by measuring particle ratios in the yield associated with a high-pT trigger particle. These measurements can potentially further constrain the models of particle production since they are sensitive to the difference between particles from a jet and particles that are produced in the bulk. We start by developing a particle identification method that uses both the specific energy loss of a particle and the time of flight. From there, we presen...

  17. Charged particle multiplicities in heavy and light quark initiated events above the $Z^0$ peak

    CERN Document Server

    Abbiendi, G.; Akesson, P.F.; Alexander, G.; Allison, John; Amaral, P.; Anagnostou, G.; Anderson, K.J.; Arcelli, S.; Asai, S.; Axen, D.; Azuelos, G.; Bailey, I.; Barberio, E.; Barlow, R.J.; Batley, R.J.; Bechtle, P.; Behnke, T.; Bell, Kenneth Watson; Bell, P.J.; Bella, G.; Bellerive, A.; Benelli, G.; Bethke, S.; Biebel, O.; Bloodworth, I.J.; Boeriu, O.; Bock, P.; Bonacorsi, D.; Boutemeur, M.; Braibant, S.; Brigliadori, L.; Brown, Robert M.; Buesser, K.; Burckhart, H.J.; Campana, S.; Carnegie, R.K.; Caron, B.; Carter, A.A.; Carter, J.R.; Chang, C.Y.; Charlton, David G.; Csilling, A.; Cuffiani, M.; Dado, S.; Dallison, S.; De Roeck, A.; De Wolf, E.A.; Desch, K.; Dienes, B.; Donkers, M.; Dubbert, J.; Duchovni, E.; Duckeck, G.; Duerdoth, I.P.; Elfgren, E.; Etzion, E.; Fabbri, F.; Feld, L.; Ferrari, P.; Fiedler, F.; Fleck, I.; Ford, M.; Frey, A.; Furtjes, A.; Gagnon, P.; Gary, John William; Gaycken, G.; Geich-Gimbel, C.; Giacomelli, G.; Giacomelli, P.; Giunta, Marina; Goldberg, J.; Gross, E.; Grunhaus, J.; Gruwe, M.; Gunther, P.O.; Gupta, A.; Hajdu, C.; Hamann, M.; Hanson, G.G.; Harder, K.; Harel, A.; Harin-Dirac, M.; Hauschild, M.; Hauschildt, J.; Hawkes, C.M.; Hawkings, R.; Hemingway, R.J.; Hensel, C.; Herten, G.; Heuer, R.D.; Hill, J.C.; Hoffman, Kara Dion; Homer, R.J.; Horvath, D.; Howard, R.; Igo-Kemenes, P.; Ishii, K.; Jeremie, H.; Jovanovic, P.; Junk, T.R.; Kanaya, N.; Kanzaki, J.; Karapetian, G.; Karlen, D.; Kartvelishvili, V.; Kawagoe, K.; Kawamoto, T.; Keeler, R.K.; Kellogg, R.G.; Kennedy, B.W.; Kim, D.H.; Klein, K.; Klier, A.; Kluth, S.; Kobayashi, T.; Kobel, M.; Komamiya, S.; Kormos, Laura L.; Kramer, T.; Kress, T.; Krieger, P.; von Krogh, J.; Krop, D.; Kruger, K.; Kuhl, T.; Kupper, M.; Lafferty, G.D.; Landsman, H.; Lanske, D.; Layter, J.G.; Leins, A.; Lellouch, D.; Lettso, J.; Levinson, L.; Lillich, J.; Lloyd, S.L.; Loebinger, F.K.; Lu, J.; Ludwig, J.; Macpherson, A.; Mader, W.; Marcellini, S.; Marchant, T.E.; Martin, A.J.; Martin, J.P.; Masetti, G.; Mashimo, T.; Mattig, Peter; McDonald, W.J.; McKenna, J.; McMahon, T.J.; McPherson, R.A.; Meijers, F.; Mendez-Lorenzo, P.; Menges, W.; Merritt, F.S.; Mes, H.; Michelini, A.; Mihara, S.; Mikenberg, G.; Miller, D.J.; Moed, S.; Mohr, W.; Mori, T.; Mutter, A.; Nagai, K.; Nakamura, I.; Neal, H.A.; Nisius, R.; O'Neale, S.W.; Oh, A.; Okpara, A.; Oreglia, M.J.; Orito, S.; Pahl, C.; Pasztor, G.; Pater, J.R.; Patrick, G.N.; Pilcher, J.E.; Pinfold, J.; Plane, David E.; Poli, B.; Polok, J.; Pooth, O.; Przybycien, M.; Quadt, A.; Rabbertz, K.; Rembser, C.; Renkel, P.; Rick, H.; Roney, J.M.; Rosati, S.; Rozen, Y.; Runge, K.; Sachs, K.; Saeki, T.; Sahr, O.; Sarkisyan, E.K.G.; Schaile, A.D.; Schaile, O.; Scharff-Hansen, P.; Schieck, J.; Schoerner-Sadenius, Thomas; Schroder, Matthias; Schumacher, M.; Schwick, C.; Scott, W.G.; Seuster, R.; Shears, T.G.; Shen, B.C.; Sherwood, P.; Siroli, G.; Skuja, A.; Smith, A.M.; Sobie, R.; Soldner-Rembold, S.; Spano, F.; Stahl, A.; Stephens, K.; Strom, David M.; Strohmer, R.; Tarem, S.; Tasevsky, M.; Taylor, R.J.; Teuscher, R.; Thomson, M.A.; Torrence, E.; Toya, D.; Tran, P.; Trefzger, T.; Tricoli, A.; Trigger, I.; Trocsanyi, Z.; Tsur, E.; Turner-Watson, M.F.; Ueda, I.; Ujvari, B.; Vachon, B.; Vollmer, C.F.; Vannerem, P.; Verzocchi, M.; Voss, H.; Vossebeld, J.; Waller, D.; Ward, C.P.; Ward, D.R.; Watkins, P.M.; Watson, A.T.; Watson, N.K.; Wells, P.S.; Wengler, T.; Wermes, N.; Wetterling, D.; Wilson, G.W.; Wilson, J.A.; Wolf, G.; Wyatt, T.R.; Yamashita, S.; Zer-Zion, D.; Zivkovic, Lidija

    2002-01-01

    We have measured the mean charged particle multiplicities separately for bbbar, ccbar and light quark (uubar, ddbar, ssbar) initiated events produced in e+e- annihilations at LEP. The data were recorded with the OPAL detector at eleven different energies above Z0 peak, corresponding to the full statistics collected at LPE1.5 and LEP2. The difference in mean charged and particle multiplicities for bbbar and light quark events, delta_bl, measured over this energy range is consistent with an energy independent behaviour, as predicted by QCD, but is inconsistent with the prediction of a more phenomenological approach which assumes that the multiplicity accompanying the decay of a heavy quark is independent of the quark mass itself. Our results, which can be combined into the single measurement delta_bl = 3.44+-0.40(stat)+-0.89(syst) at a luminosity weighted average centre-of mass energy of 195 GeV, are also consistent with an energy independent behaviour as extrapolated from lower energy data.

  18. Study of the angular correlation between heavy-flavour decay electrons and charged unidentified particles in pp and p-Pb collisions with ALICE

    CERN Document Server

    Pereira De Oliveira Filho, Elienos

    The aim of relativistic heavy-ion collisions is to investigate the properties of the Quark-Gluon Plasma (QGP) phase, that is achieved at high-enough temperatures and/or densities. In this context, light on heavy-ion collisions (e. g. p-Pb) are used to assess Cold Nuclear Matter effects (CNM), while elementary hadronic collisions (e. g. proton-proton) provide tests for QCD (Quantum Chromodynamics) based calculations and baseline for studies with heavy- ions. Heavy quarks, i. e. charm and beauty, are very convenient in the characterization of the QGP. They are produced via initial hard parton-parton scatterings at the early stages of the collision and, therefore, they are a self-generated probe for the system created in the reaction. In this work the angular correlation between electrons from heavy-flavour hadron decays and charged particles was studied in pp (2.76 and 7 TeV) and p-Pb (5.02 TeV) collisions at the CERN Large Hadron Collider, using the ALICE detector. The correlation strengths were evaluated as a...

  19. High mass asymmetry in spontaneous and induced desintegration of heavy nuclei

    International Nuclear Information System (INIS)

    Tavares, O.A.P.

    1978-01-01

    The experimental and theoretical results related to a new rupture mode of heavy ions (A>230) in mass fragments more different than ordinary ission products, are presented and disussed. Experiences of long exposure time by nuclear emulsion technique, show that, the U 238 is also a spontaneous emitter of ions with mass number between 20 and 70. The results are interpreted as a high mass asymmetry in fission process or as a nucleon cluster emission mechanism by potential barrier penetration. Preliminary estimation show good agreement with experimental results for U 238 . Glass laminas with uranium thin films prepared 16 years ago, are also analysed aiming to confirm these results. Several experiences with nuclear emulsions and mica sandwich, and radiochemical data show to be possible heavy ion emission from U 238 induced by photons of low energy as well as neutrons of reactor (M.C.K.) [pt

  20. Heavy-light fermion mixtures at unitarity

    Energy Technology Data Exchange (ETDEWEB)

    Gezerlis, Alexandros [Los Alamos National Laboratory; Carlson, Joseph [Los Alamos National Laboratory; Gandol, S [UNIV. ILL; Schmidt, E [ITALY

    2009-01-01

    We investigate fermion pairing in the unitary regime for a mass ratio corresponding to a {sup 6}Li-{sup 40}K mixture using quantum Monte Carlo methods. The ground-state energy and the average light- and heavy-particle excitation spectrum for the unpolarized superfluid state are nearly independent of the mass ratio. In the majority light system, the polarized superfluid is close to the energy of a phase separated mixture of nearly fully polarized normal and unpolarized superfluid. For a majority of heavy particles, we find an energy minimum for a normal state with a ratio of {approx}3:1 heavy to light particles. A slight increase in attraction to k{sub F}a{approx}2.5 yields a ground state energy of nearly zero for this ratio. A cold unpolarized system in a harmonic trap at unitarity should phase separate into three regions, with a shell of unpolarized superfluid in the middle.

  1. An intranuclear cascade calculation of high-energy heavy-ion interactions

    International Nuclear Information System (INIS)

    Yariv, Y.; Fraenkel, Z.

    1979-01-01

    The intranuclear cascade model of Chen is extended to high-energy reactions between two heavy ions. The results of the calculations are compared with experimental results for the inclusive proton and pion cross sections, two-particle correlations, particle multiplicity distributions and spallation cross section distributions from light ( 12 C+ 12 C) to heavy( 40 Ar + 238 U) projectile-target systems in the laboratory bombarding energy range E/A=250-1000 MeV. The comparison shows that the model is fairly successful in reproducing the various aspects of high-energy reactions between heavy ions. It is also shown that the assumption that high particle multiplicities are indicative of ''central'' (small impact parameter) collisions are well founded for heavy projectile-target systems. (B.G.)

  2. High-energy elastic recoil detection heavy ions for light element analysis

    International Nuclear Information System (INIS)

    Goppelt-Langer, P.; Yamamoto, S.; Takeshita, H.; Aoki, Y.; Naramoto, H.

    1994-01-01

    The detection of light and medium heavy elements in not homogeneous solids is a severe problem in ion beam analysis. Heavy elements can be detected by the well established Rutherford backscattering technique (RBS). In a homogeneous host material most impurities can be easily analyzed by secondary ion mass spectroscopy (SIMS). Some isotopes ( 3 He, 6 Li, 10 B) can be measured by nuclear reaction analysis (NRA) using thermal neutrons inducing (n, p) or (n, α) reactions. Others can be detected by energetic ion beams by nuclear reactions (e.g. 15 N( 1 H, αγ) 12 C for analysis of hydrogen). A high content of H, D or T can be also determined by elastic recoil detection using an energetic He beam. The latter technique has been developed to a universal method for detection of light and heavy elements in any target, using a high energetic heavy ion beam and a detector system, which is able to identify the recoils and delivers energy and position of the particles. (author)

  3. Soft radiation in heavy-particle pair production: All-order colour structure and two-loop anomalous dimension

    International Nuclear Information System (INIS)

    Beneke, M.; Falgari, P.; Schwinn, C.

    2010-01-01

    We consider the total production cross section of heavy coloured particle pairs in hadronic collisions at the production threshold. We construct a basis in colour space that diagonalizes to all orders in perturbation theory the soft function, which appears in a new factorization formula for the combined resummation of soft gluon and Coulomb gluon effects. This extends recent results on the structure of soft anomalous dimensions and allows us to determine an analytic expression for the two-loop soft anomalous dimension at threshold for all production processes of interest.

  4. Heavy particle clinical radiotherapy trial at Lawrence Berkeley Laboratory. Progress report, July 1975-July 1979

    International Nuclear Information System (INIS)

    Castro, J.R.

    1979-01-01

    The primary objectives of the clinical radiotherapy program are: to evaluate the potential of improved dose localization particularly as exemplified by helium ion irradiation; and to evaluate the combined potential of improved dose localization and increased biologic effect available with heavier ions such as carbon, neon, and argon. It was possible to make modifications rapidly to provide for large field, fractionated, Bragg peak irradiation at the 184-inch cyclotron with the helium ion beam. This allowed the opportunity to gain experience with charged particle irradiation treatment techniques, patient immobilization techniques, treatment planning and dosimetry studies including the utilization of CT scanning for tumor localization and charged particle dose distributions as well as beginning studies in compensating for tissue inhomogeneities in the beam path. These treatment techniques have been directly transferable to the Bevalac facility where a similar patient positioner has been installed for human irradiation with heavier particles. For the studies both with helium and now with heavier particles, patients with multiple skin and subcutaneous metastatic nodules for evaluation of skin RBE data and patients with locally advanced and/or unresectable tumors unlikely to be effectively treated by any conventional modality were sought. In order to facilitate intercomparison with megavoltage irradiation techniques, a conventional dose fractionation scheme has been adopted. A few exceptions to this dose specification scheme have been patients in which pulmonary, subcutaneous or skin nodules have been irradiated with larger fraction sizes ranging up to 400 rads per fraction in order to obtain clinical RBE studies in 8 to 10 fractions of heavy particles

  5. Very heavy dark Skyrmions

    International Nuclear Information System (INIS)

    Dick, Rainer

    2017-01-01

    A dark sector with a solitonic component provides a means to circumvent the problem of generically low annihilation cross sections of very heavy dark matter particles. At the same time, enhanced annihilation cross sections are necessary for indirect detection of very heavy dark matter components beyond 100 TeV. Non-thermally produced dark matter in this mass range could therefore contribute to the cosmic γ-ray and neutrino flux above 100 TeV, and massive Skyrmions provide an interesting framework for the discussion of these scenarios. Therefore a Higgs portal and a neutrino portal for very heavy Skyrmion dark matter are discussed. The Higgs portal model demonstrates a dark mediator bottleneck, where limitations on particle annihilation cross sections will prevent a signal from the potentially large soliton annihilation cross sections. This problem can be avoided in models where the dark mediator decays. This is illustrated by the neutrino portal for Skyrmion dark matter. (orig.)

  6. Very heavy dark Skyrmions

    Energy Technology Data Exchange (ETDEWEB)

    Dick, Rainer [University of Saskatchewan, Department of Physics and Engineering Physics, Saskatoon, SK (Canada)

    2017-12-15

    A dark sector with a solitonic component provides a means to circumvent the problem of generically low annihilation cross sections of very heavy dark matter particles. At the same time, enhanced annihilation cross sections are necessary for indirect detection of very heavy dark matter components beyond 100 TeV. Non-thermally produced dark matter in this mass range could therefore contribute to the cosmic γ-ray and neutrino flux above 100 TeV, and massive Skyrmions provide an interesting framework for the discussion of these scenarios. Therefore a Higgs portal and a neutrino portal for very heavy Skyrmion dark matter are discussed. The Higgs portal model demonstrates a dark mediator bottleneck, where limitations on particle annihilation cross sections will prevent a signal from the potentially large soliton annihilation cross sections. This problem can be avoided in models where the dark mediator decays. This is illustrated by the neutrino portal for Skyrmion dark matter. (orig.)

  7. Statistical and direct decay of high-lying single-particle excitations

    International Nuclear Information System (INIS)

    Gales, S.

    1993-01-01

    Transfer reactions induced by hadronic probes at intermediate energies have revealed a rich spectrum of high-lying excitations embedded in the nuclear continuum. The investigation of their decay properties is believed to be a severe test of their microscopic structure as predicted by microscopic nuclear models. In addition the degree of damping of these simple modes in the nuclear continuum can be obtained by means of the measured particle (n,p) decay branching ratios. The neutron and proton decay studies of high-lying single-particle states in heavy nuclei are presented. (author). 13 refs., 9 figs

  8. Determination of cross sections of nuclear reactions to use Al as monitoring foil in heavy ion irradiation with 20Ne projectile

    International Nuclear Information System (INIS)

    Chowdhury, D.P.; Datta, J.; Guin, R.; Verma, R.

    2009-01-01

    The beam current is generally accurately measured using monitoring foils during the irradiation of thick samples by high energy ion beams. The cross sections of many nuclear reactions induced by light particles are available in literature for use as monitoring foil. However, such cross sections of heavy ion induced reactions are not reported much for their use in applied works. We have determined cross sections of two nuclear reactions, 27 Al ( 20 Ne,2p2n) 43 Sc and 27 Al ( 20 Ne, 2pn) 44m Sc, to use Al as monitoring foil for the irradiation with 20 Ne heavy ion beam. (author)

  9. Alpha Particles Induce Autophagy in Multiple Myeloma Cells.

    Science.gov (United States)

    Gorin, Jean-Baptiste; Gouard, Sébastien; Ménager, Jérémie; Morgenstern, Alfred; Bruchertseifer, Frank; Faivre-Chauvet, Alain; Guilloux, Yannick; Chérel, Michel; Davodeau, François; Gaschet, Joëlle

    2015-01-01

    Radiation emitted by the radionuclides in radioimmunotherapy (RIT) approaches induce direct killing of the targeted cells as well as indirect killing through the bystander effect. Our research group is dedicated to the development of α-RIT, i.e., RIT using α-particles especially for the treatment of multiple myeloma (MM). γ-irradiation and β-irradiation have been shown to trigger apoptosis in tumor cells. Cell death mode induced by (213)Bi α-irradiation appears more controversial. We therefore decided to investigate the effects of (213)Bi on MM cell radiobiology, notably cell death mechanisms as well as tumor cell immunogenicity after irradiation. Murine 5T33 and human LP-1 MM cell lines were used to study the effects of such α-particles. We first examined the effects of (213)Bi on proliferation rate, double-strand DNA breaks, cell cycle, and cell death. Then, we investigated autophagy after (213)Bi irradiation. Finally, a coculture of dendritic cells (DCs) with irradiated tumor cells or their culture media was performed to test whether it would induce DC activation. We showed that (213)Bi induces DNA double-strand breaks, cell cycle arrest, and autophagy in both cell lines, but we detected only slight levels of early apoptosis within the 120 h following irradiation in 5T33 and LP-1. Inhibition of autophagy prevented (213)Bi-induced inhibition of proliferation in LP-1 suggesting that this mechanism is involved in cell death after irradiation. We then assessed the immunogenicity of irradiated cells and found that irradiated LP-1 can activate DC through the secretion of soluble factor(s); however, no increase in membrane or extracellular expression of danger-associated molecular patterns was observed after irradiation. This study demonstrates that (213)Bi induces mainly necrosis in MM cells, low levels of apoptosis, and autophagy that might be involved in tumor cell death.

  10. Heavy flavour production at RHIC and LHC

    Directory of Open Access Journals (Sweden)

    Innocenti Gian Michele

    2018-01-01

    Full Text Available In this proceedings, I present selected experimental results on heavy-flavour production at RHIC and at the LHC, which were presented at the Strangeness in Quark Matter 2017 conference. I will present a brief introduction to the heavy-flavour physics in heavy ion collisions and I will focus on recents measurements of in-medium energy loss and and collective properties of heavy-flavour particles, which provided important information on the mechanisms of heavy flavour interaction with the hot and dense medium created in ultra-relativistic heavy-ion collisions.

  11. Special topics. Advances of radiation biology in heavy particle therapy- review. Effects of photon and heavy particle irradiation on metastasis and angiogenesis

    International Nuclear Information System (INIS)

    Ogata, Toshiyuki; Teshima, Teruki; Takahashi, Yutaka; Matsuura, Nariaki; Furusawa, Yoshiya

    2009-01-01

    Described are effects of photon and heavy particle (HP) irradiation on the process of tumor metastasis (MT) and accompanying angiogenesis (AG) at molecular, cellular and animal levels. Recent animal studies of molecular mechanistic elucidation of increased MT by photon have revealed the participation of activated proteins like matrix metalloproteinase (MMP) and integrins, of increased secretion of growth factors, of up-regulation of receptors like for that of urokinase-type plasminogen activator under hypoxia, and so on. Authors have studied the effect of HP on cellular MMP and integrins and on MT in tumor-bearing mice, and suggested a suppression of MT by HP. Vascular endothelial cells, playing a major role in AG, are resistant to low dose (e.g., 3 Gy) radiation and sensitive to higher dose (9-20 Gy), which has resulted in various complicating findings on MT. There are also many findings on MT and/or AG relations with various treatments like surgical or photon treatment of the primary tumor and AG suppressive substances, where further examinations are necessary for practical use of photon/drug therapy to prevent MT through AG participation. Authors have implicated in vitro that HP, even at low dose (0.1 Gy, sublethal), can suppress MT through AG mechanism. Thus prevention of MT by HP is thought promising in future when their mutual interaction is elucidated more clearly. (K.T.)

  12. Radiation-induced transmission spectral variations of Ce3+-doped heavy germanate glasses

    International Nuclear Information System (INIS)

    Yang Yunxia; Baccaro, S.; Cecilia, A.; Rao Jinhua; Zhang Junbiao; Xia Fang; Chen Guorong

    2005-01-01

    Radiation-induced transmission spectral variations of Ce 3+ -doped heavy germanate glasses used as scintillating materials are presented. Glass matrix contains mainly GeO 2 , BaO and Gd 2 O 3 with a density higher than 5 g/cm 3 . Glasses are melted in the different atmosphere. The transmission spectra of glasses before and after radiation treatments are measured and compared. Unlike exhibiting the monotonous deterioration effect on the glass matrix, radiation plays the radiation protection role, even making enhanced transmission of Ce 3+ -doped glasses, depending upon glass melting atmosphere and radiation dose. Radiation-induced reducing and oxidizing mechanism is proposed to explain phenomena

  13. Elaboration by ion implantation of cobalt nano-particles in silica layers and modifications of their properties by electron and swift heavy ion irradiations; Elaboration par implantation ionique de nanoparticules de cobalt dans la silice et modifications de leurs proprietes sous irradiation d'electrons et d'ions de haute energie

    Energy Technology Data Exchange (ETDEWEB)

    D' Orleans, C

    2003-07-15

    This work aims to investigate the capability of ion irradiations to elaborate magnetic nano-particles in silica layers, and to modify their properties. Co{sup +} ions have been implanted at 160 keV at fluences of 2.10{sup 16}, 5.10{sup 16} and 10{sup 17} at/cm{sup 2}, and at temperatures of 77, 295 and 873 K. The dependence of the particle size on the implantation fluence, and more significantly on the implantation temperature has been shown. TEM (transmission electronic microscopy) observations have shown a mean diameter varying from 1 nm for implantations at 2.10{sup 16} Co{sup +}/cm{sup 2} at 77 K, to 9.7 nm at 10{sup 17} Co{sup +}/cm{sup 2} at 873 K. For high temperature implantations, two regions of particles appear. Simulations based on a kinetic 3-dimensional lattice Monte Carlo method reproduce quantitatively the features observed for implantations. Thermal treatments induce the ripening of the particles. Electron irradiations at 873 K induce an important increase in mean particle sizes. Swift heavy ion irradiations also induce the ripening of the particles for low fluences, and an elongation of the particles in the incident beam direction for high fluences, resulting in a magnetic anisotropy. Mechanisms invoked in thermal spike model could also explain this anisotropic growth. (author)

  14. NMR relaxation induced by iron oxide particles: testing theoretical models.

    Science.gov (United States)

    Gossuin, Y; Orlando, T; Basini, M; Henrard, D; Lascialfari, A; Mattea, C; Stapf, S; Vuong, Q L

    2016-04-15

    Superparamagnetic iron oxide particles find their main application as contrast agents for cellular and molecular magnetic resonance imaging. The contrast they bring is due to the shortening of the transverse relaxation time T 2 of water protons. In order to understand their influence on proton relaxation, different theoretical relaxation models have been developed, each of them presenting a certain validity domain, which depends on the particle characteristics and proton dynamics. The validation of these models is crucial since they allow for predicting the ideal particle characteristics for obtaining the best contrast but also because the fitting of T 1 experimental data by the theory constitutes an interesting tool for the characterization of the nanoparticles. In this work, T 2 of suspensions of iron oxide particles in different solvents and at different temperatures, corresponding to different proton diffusion properties, were measured and were compared to the three main theoretical models (the motional averaging regime, the static dephasing regime, and the partial refocusing model) with good qualitative agreement. However, a real quantitative agreement was not observed, probably because of the complexity of these nanoparticulate systems. The Roch theory, developed in the motional averaging regime (MAR), was also successfully used to fit T 1 nuclear magnetic relaxation dispersion (NMRD) profiles, even outside the MAR validity range, and provided a good estimate of the particle size. On the other hand, the simultaneous fitting of T 1 and T 2 NMRD profiles by the theory was impossible, and this occurrence constitutes a clear limitation of the Roch model. Finally, the theory was shown to satisfactorily fit the deuterium T 1 NMRD profile of superparamagnetic particle suspensions in heavy water.

  15. Groomed jets in heavy-ion collisions: sensitivity to medium-induced bremsstrahlung

    Energy Technology Data Exchange (ETDEWEB)

    Mehtar-Tani, Yacine [Institute of Nuclear Theory, University of Washington,Seattle, WA 98195-1550 (United States); Tywoniuk, Konrad [Theoretical Physics Department, CERN,1211 Geneva 23 (Switzerland)

    2017-04-21

    We argue that contemporary jet substructure techniques might facilitate a more direct measurement of hard medium-induced gluon bremsstrahlung in heavy-ion collisions, and focus specifically on the “soft drop declustering” procedure that singles out the two leading jet substructures. Assuming coherent jet energy loss, we find an enhancement of the distribution of the energy fractions shared by the two substructures at small subjet energy caused by hard medium-induced gluon radiation. Departures from this approximation are discussed, in particular, the effects of colour decoherence and the contamination of the grooming procedure by soft background. Finally, we propose a complementary observable, that is the ratio of the two-pronged probability in Pb-Pb to proton-proton collisions and discuss its sensitivity to various energy loss mechanisms.

  16. Groomed jets in heavy-ion collisions: sensitivity to medium-induced bremsstrahlung

    CERN Document Server

    Mehtar-Tani, Yacine

    2017-04-21

    We argue that contemporary jet substructure techniques might facilitate a more direct measurement of hard medium-induced gluon bremsstrahlung in heavy-ion collisions, and focus specifically on the "soft drop declustering" procedure that singles out the two leading jet substructures. Assuming coherent jet energy loss, we find an enhancement of the distribution of the energy fractions shared by the two substructures at small subjet energy caused by hard medium-induced gluon radiation. Departures from this approximation are discussed, in particular, the effects of colour decoherence and the contamination of the grooming procedure by soft background. Finally, we propose a complementary observable, that is the ratio of the two-pronged probability in Pb-Pb to proton-proton collisions and discuss its sensitivity to various energy loss mechanisms.

  17. Groomed jets in heavy-ion collisions: sensitivity to medium-induced bremsstrahlung

    Science.gov (United States)

    Mehtar-Tani, Yacine; Tywoniuk, Konrad

    2017-04-01

    We argue that contemporary jet substructure techniques might facilitate a more direct measurement of hard medium-induced gluon bremsstrahlung in heavy-ion collisions, and focus specifically on the "soft drop declustering" procedure that singles out the two leading jet substructures. Assuming coherent jet energy loss, we find an enhancement of the distribution of the energy fractions shared by the two substructures at small subjet energy caused by hard medium-induced gluon radiation. Departures from this approximation are discussed, in particular, the effects of colour decoherence and the contamination of the grooming procedure by soft background. Finally, we propose a complementary observable, that is the ratio of the two-pronged probability in Pb-Pb to proton-proton collisions and discuss its sensitivity to various energy loss mechanisms.

  18. Groomed jets in heavy-ion collisions: sensitivity to medium-induced bremsstrahlung

    International Nuclear Information System (INIS)

    Mehtar-Tani, Yacine; Tywoniuk, Konrad

    2017-01-01

    We argue that contemporary jet substructure techniques might facilitate a more direct measurement of hard medium-induced gluon bremsstrahlung in heavy-ion collisions, and focus specifically on the “soft drop declustering” procedure that singles out the two leading jet substructures. Assuming coherent jet energy loss, we find an enhancement of the distribution of the energy fractions shared by the two substructures at small subjet energy caused by hard medium-induced gluon radiation. Departures from this approximation are discussed, in particular, the effects of colour decoherence and the contamination of the grooming procedure by soft background. Finally, we propose a complementary observable, that is the ratio of the two-pronged probability in Pb-Pb to proton-proton collisions and discuss its sensitivity to various energy loss mechanisms.

  19. The effects of particle size distribution and induced unpinning during grain growth

    International Nuclear Information System (INIS)

    Thompson, G.S.; Rickman, J.M.; Harmer, M.P.; Holm, E.A.

    1996-01-01

    The effect of a second-phase particle size distribution on grain boundary pinning was studied using a Monte Carlo simulation technique. Simulations were run using a constant number density of both whisker and rhombohedral particles, and the effect of size distribution was studied by varying the standard deviation of the distribution around a constant mean particle size. The results of present simulations indicate that, in accordance with the stereological assumption of the topological pinning model, changes in distribution width had no effect on the pinned grain size. The effect of induced unpinning of particles on microstructure was also studied. In contrast to predictions of the topological pinning model, a power law dependence of pinned grain size on particle size was observed at T=0.0. Based on this, a systematic deviation to the stereological predictions of the topological pinning model is observed. The results of simulations at higher temperatures indicate an increasing power law dependence of pinned grain size on particle size, with the slopes of the power law dependencies fitting an Arrhenius relation. The effect of induced unpinning of particles was also studied in order to obtain a correlation between particle/boundary concentration and equilibrium grain size. The results of simulations containing a constant number density of monosized rhombohedral particles suggest a strong power law correlation between the two parameters. copyright 1996 Materials Research Society

  20. Hiding a Heavy Higgs Boson at the 7 TeV LHC

    Energy Technology Data Exchange (ETDEWEB)

    Bai, Yang; Fan, JiJi; Hewett, JoAnne L.

    2012-03-20

    A heavy Standard Model Higgs boson is not only disfavored by electroweak precision observables but is also excluded by direct searches at the 7 TeV LHC for a wide range of masses. Here, we examine scenarios where a heavy Higgs boson can be made consistent with both the indirect constraints and the direct null searches by adding only one new particle beyond the Standard Model. This new particle should be a weak multiplet in order to have additional contributions to the oblique parameters. If it is a color singlet, we find that a heavy Higgs with an intermediate mass of 200-300 GeV can decay into the new states, suppressing the branching ratios for the standard model modes, and thus hiding a heavy Higgs at the LHC. If the new particle is also charged under QCD, the Higgs production cross section from gluon fusion can be reduced significantly due to the new colored particle one-loop contribution. Current collider constraints on the new particles allow for viable parameter space to exist in order to hide a heavy Higgs boson. We categorize the general signatures of these new particles, identify favored regions of their parameter space and point out that discovering or excluding them at the LHC can provide important indirect information for a heavy Higgs. Finally, for a very heavy Higgs boson, beyond the search limit at the 7 TeV LHC, we discuss three additional scenarios where models would be consistent with electroweak precision tests: including an additional vector-like fermion mixing with the top quark, adding another U(1) gauge boson and modifying triple-gauge boson couplings.

  1. Scattering of mass-3 projectiles from heavy nuclei

    International Nuclear Information System (INIS)

    Mukhopadyay, S.; Srivastava, D.K.; Ganguly, N.K.

    1976-01-01

    The interaction between heavy ions is a subject of great interest. It is well known that α-particle scattering shows most of the features which are observed in heavy ion scattering. In as much as mass-3 system is intermediate between heavy and light particles it will be interesting to investigate the scattering of mass-3 projectiles to see if it is possible to extend it to study the heavy ion scattering. Indeed; it has been seen that the 'molecular type' potentials, with a soft repulsive core and a shallow attractive well used for heavy ion collisions can be used to fit the elastic scattering data of mass-3 projectiles also. In the first part of this paper, a description is given of how this potential is generated with a special emphasis on saturation and second order effect through a density dependent interaction between nucleon and mass-3 projectiles. In the second part it is shown that the asymmetry dependence observed in the potential describing the scattering of mass-3 particles from heavier nuclei actually originates from the isospin interaction, when triton and helion are treated as two members of an isospin doublet. (Auth.)

  2. Heavy ion radiation biology research facility and ongoing activities at the Inter-University Accelerator Centre, New Delhi

    International Nuclear Information System (INIS)

    Sarma, Asitikantha

    2014-01-01

    Heavy Ion Radiation Biology is an interdisciplinary science involving use of charged particle accelerator in the study of molecular biology. It is the study of the interaction of a beam of swift heavy ions with a biological system. In contrast to the sparsely ionizing photon or electron radiation, the high velocity charged heavy ions leave a track of densely populated ionization sites resulting in clustered DNA damage. The growing interest in this field encompasses the studies in gene expression, mechanisms of cell death, DNA damage and repair, signal transduction etc. induced because of this unique assault on the genetic material. IUAC radiation biology programme is focused on the in-vitro studies of different effects of heavy ion irradiation on eukaryotic cells. The facility provides a laboratory for pre and post irradiation treatment of samples. The irradiation system called ASPIRE (Automatic Sample Positioning for Irradiation in Radiation Biology Experiments) is installed at the dedicated Radiation Biology Beam line. It produces a nearly uniform flux distribution over a irradiation field of 40 mm diameter. The particle doses can be preselected and repeated within inherent statistical accuracy. The particle energy can also be measured. The facility is at present utilized by the University researchers of India. A few results obtained by the investigators would be presented. The outcome of the research in heavy ion radiation biology would be of immense use in augmenting the efficacy of Hadron therapy of cancer. The results would also contribute to the field of space radiation protection. It would also help in understanding the phenomena subsequent to complex DNA damage. (author)

  3. Searching for Heavy Photons with Detached Verices in the Heavy Photon Search Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Szumila-Vance, Holly [Old Dominion Univ., Norfolk, VA (United States); Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States)

    2017-08-01

    The Jefferson Lab Heavy Photon Search (HPS) experiment is searching for a hypothetical massive particle called the heavy photon which could mediate a dark electromagnetic-type force. If heavy photons kinetically mix with Standard Model photons, they may be radiated by electrons scattering from a heavy nucleus and then decay to e+e- pairs. HPS uniquely searches for heavy photons that either decay at the target or a measurable distance after. The experiment utilizes a silicon vertex tracker (SVT) for momentum and vertex reconstruction, together with an electromagnetic calorimeter for measuring particle energies and triggering events. The HPS experiment took its first data during the spring 2015 engineering run using a 1 GeV electron beam incident on a tungsten target and its second data in the spring of 2016 at a beam energy of 2.3 GeV. The 2015 run obtained two days of production data that was used for the first physics results. The analysis of the data was conducted as a blinded analysis by tuning cuts on 10% of the data. This dissertation discusses the displaced vertex search for heavy photons in the 2015 engineering run. It describes the theoretical motivation for looking for heavy photons and provides an overview of the HPS experimental design and performance. The performance details of the experiment are primarily derived from the 2015 engineering run with some discussion from the higher energy running in 2016. This dissertation further discusses the cuts used to optimize the displaced vertex search and the results of the search. The displaced vertex search did not set a limit on the heavy photon but did validate the methodology for conducting the search. Finally, we used the full data set to make projections and guide future analyses.

  4. Effect of heavy atoms on photochemically induced dynamic nuclear polarization in liquids

    Science.gov (United States)

    Okuno, Yusuke; Cavagnero, Silvia

    2018-01-01

    Given its short hyperpolarization time (∼10-6 s) and mostly non-perturbative nature, photo-chemically induced dynamic nuclear polarization (photo-CIDNP) is a powerful tool for sensitivity enhancement in nuclear magnetic resonance. In this study, we explore the extent of 1H-detected 13C nuclear hyperpolarization that can be gained via photo-CIDNP in the presence of small-molecule additives containing a heavy atom. The underlying rationale for this methodology is the well-known external-heavy-atom (EHA) effect, which leads to significant enhancements in the intersystem-crossing rate of selected photosensitizer dyes from photoexcited singlet to triplet. We exploited the EHA effect upon addition of moderate amounts of halogen-atom-containing cosolutes. The resulting increase in the transient triplet-state population of the photo-CIDNP sensitizer fluorescein resulted in a significant increase in the nuclear hyperpolarization achievable via photo-CIDNP in liquids. We also explored the internal-heavy-atom (IHA) effect, which is mediated by halogen atoms covalently incorporated into the photosensitizer dye. Widely different outcomes were achieved in the case of EHA and IHA, with EHA being largely preferable in terms of net hyperpolarization.

  5. Implications of heavy-ion induced satellite x-ray emission. I. Introduction

    International Nuclear Information System (INIS)

    Raman, S.; Vane, C.R.

    1983-01-01

    Regardless of how they are induced, x-ray spectra are sensitive to the chemical environment of the emitting atom and can yield information on the atomic and electronic structure of host materials. Those spectra resulting from light ion and heavy ion excitations are the main topics covered in this series of papers. Highly energetic heavy ions are capable of producing multiple innershell ionization. The resulting spectrum of x-rays from a particular target atom is composed of a complex series of satellite lines. Environmental effects give rise to the redistribution of intensity from one satellite group to another. These changes can be correlated with one satellite group to another. These changes can be correlated with bulk chemical properties (valence electron densities, effective charges, covalencies, etc.). The possibility of obtaining new chemical information (for example, in implanted materials and in metal alloys) exists but requires greater experimental and theoretical understanding of both parametric variations and the fine structure of satellite lines

  6. Heavy-ion collimation at the Large Hadron Collider. Simulations and measurements

    Energy Technology Data Exchange (ETDEWEB)

    Hermes, Pascal Dominik

    2016-12-19

    The CERN Large Hadron Collider (LHC) stores and collides proton and {sup 208}Pb{sup 82+} beams of unprecedented energy and intensity. Thousands of superconducting magnets, operated at 1.9 K, guide the very intense and energetic particle beams, which have a large potential for destruction. This implies the demand for a multi-stage collimation system to provide protection from beam-induced quenches or even hardware damage. In heavy-ion operation, ion fragments with significant rigidity offsets can still scatter out of the collimation system. When they irradiate the superconducting LHC magnets, the latter risk to quench (lose their superconducting property). These secondary collimation losses can potentially impose a limitation for the stored heavy-ion beam energy. Therefore, their distribution in the LHC needs to be understood by sophisticated simulations. Such simulation tools must accurately simulate the particle motion of many different nuclides in the magnetic LHC lattice and simulate their interaction with the collimators. Previous simulation tools used simplified models for the simulation of particle-matter interaction and showed discrepancies compared to the measured loss patterns. This thesis describes the development and application of improved heavy-ion collimation simulation tools. Two different approaches are presented to provide these functionalities. In the first presented tool, called STIER, fragmentation at the primary collimator is simulated with the Monte-Carlo event generator FLUKA. The ion fragments scattered out of the primary collimator are subsequently tracked as protons with ion-equivalent rigidities in the existing proton tracking tool SixTrack. This approach was used to prepare the collimator settings for the 2015 LHC heavy-ion run and its predictions allowed reducing undesired losses. More accurate simulation results are obtained with the second presented simulation tool, in which SixTrack is extended to track arbitrary heavy ions. This new

  7. Heavy-ion collimation at the Large Hadron Collider. Simulations and measurements

    International Nuclear Information System (INIS)

    Hermes, Pascal Dominik

    2016-01-01

    The CERN Large Hadron Collider (LHC) stores and collides proton and 208 Pb 82+ beams of unprecedented energy and intensity. Thousands of superconducting magnets, operated at 1.9 K, guide the very intense and energetic particle beams, which have a large potential for destruction. This implies the demand for a multi-stage collimation system to provide protection from beam-induced quenches or even hardware damage. In heavy-ion operation, ion fragments with significant rigidity offsets can still scatter out of the collimation system. When they irradiate the superconducting LHC magnets, the latter risk to quench (lose their superconducting property). These secondary collimation losses can potentially impose a limitation for the stored heavy-ion beam energy. Therefore, their distribution in the LHC needs to be understood by sophisticated simulations. Such simulation tools must accurately simulate the particle motion of many different nuclides in the magnetic LHC lattice and simulate their interaction with the collimators. Previous simulation tools used simplified models for the simulation of particle-matter interaction and showed discrepancies compared to the measured loss patterns. This thesis describes the development and application of improved heavy-ion collimation simulation tools. Two different approaches are presented to provide these functionalities. In the first presented tool, called STIER, fragmentation at the primary collimator is simulated with the Monte-Carlo event generator FLUKA. The ion fragments scattered out of the primary collimator are subsequently tracked as protons with ion-equivalent rigidities in the existing proton tracking tool SixTrack. This approach was used to prepare the collimator settings for the 2015 LHC heavy-ion run and its predictions allowed reducing undesired losses. More accurate simulation results are obtained with the second presented simulation tool, in which SixTrack is extended to track arbitrary heavy ions. This new tracking

  8. Swift heavy ion induced modification of aliphatic polymers

    Energy Technology Data Exchange (ETDEWEB)

    Hossain, Umme Habiba

    2015-01-15

    In this thesis, the high energy heavy ion induced modification of aliphatic polymers is studied. Two polymer groups, namely polyvinyl polymers (PVF, PVAc, PVA and PMMA) and fluoropolymers (PVDF, ETFE, PFA and FEP) were used in this work. Polyvinyl polymers were investigated since they will be used as insulating materials in the superconducting magnets of the new ion accelerators of the planned International Facility for Antiproton and Ion Research (FAIR) at the GSI Helmholtz-Centre of Heavy Ion Research (GSI) in Darmstadt. In order to study ion-beam induced degradation, all polymer foils were irradiated at the GSI linear accelerator UNILAC using several projectiles (U, Au, Sm, Xe) and experimentation sites (beam lines X0 and M3) over a large fluence regime (1 x 10{sup 10} - 5 x 10{sup 12} ions/cm{sup 2}). Five independent techniques, namely infrared (FT-IR) and ultraviolet-visible (UV-Vis) spectroscopy, residual gas analysis (RGA), thermal gravimetric analysis (TGA), and mass loss analysis (ML), were used to analyze the irradiated samples. FT-IR spectroscopy revealed that ion irradiation led to the decrease of characteristic band intensities showing the general degradation of the polymers, with scission of side groups and the main backbone. As a consequence of the structural modification, new bands appeared. UV-Vis transmission analysis showed an absorption edge shift from the ultraviolet region towards the visible region indicating double bond and conjugated double bond formation. On-line massspectrometric residual gas analysis showed the release of small gaseous fragment molecules. TGA analysis gave evidence of a changed thermal stability. With ML analysis, the considerable mass loss was quantified. The results of the five complementary analytical methods show how heavy ion irradiation changes the molecular structure of the polymers. Molecular degradation mechanisms are postulated. The amount of radiation damage is found to be sensitive to the used type of ionic

  9. Study of the effect of heavy ion energy on the sensitivity of electronic devices

    International Nuclear Information System (INIS)

    Raine, M.

    2011-01-01

    This thesis studies the sensitivity of advanced electronic devices in radiative environments. The work deals with the detailed modeling of the deposited energy induced by heavy-ion in matter, and the influence of taking it into account in the tools simulating the response of irradiated devices. To do so, a simulation chain was developed, combining different calculation codes at various scales. In a first step, the particle-matter interaction code Geant4 is used to model the heavy ion track. These tracks are then implemented in a TCAD simulator, in order to study the response of elementary transistors to these detailed energy deposits. This step is completed with experimental measurements. Finally, the study is extended to the circuit level, by interfacing the heavy ion tracks with a SEE prediction tool. These different steps evidence the need for taking into account the radial extension of the ion track to all simulation levels, to adequately model the response of advanced devices under heavy ion irradiations. (author) [fr

  10. Heavy metal immobilization via microbially induced carbonate precipitation and co-precipitation

    Science.gov (United States)

    Lauchnor, E. G.; Stoick, E.

    2017-12-01

    Microbially induced CaCO3 precipitation (MICP) has been successfully used in applications such as porous media consolidation and sealing of leakage pathways in the subsurface, and it has the potential to be used for remediation of metal and radionuclide contaminants in surface and groundwater. In this work, MICP is investigated for removal of dissolved heavy metals from contaminated mine discharge water via co-precipitation in CaCO3 or formation of other metal carbonates. The bacterially catalyzed hydrolysis of urea produces inorganic carbon and ammonium and increases pH and the saturation index of carbonate minerals to promote precipitation of CaCO3. Other heavy metal cations can be co-precipitated in CaCO3 as impurities or by replacing Ca2+ in the crystal lattice. We performed laboratory batch experiments of MICP in alkaline mine drainage sampled from an abandoned mine site in Montana and containing a mixture of heavy metals at near neutral pH. Both a model bacterium, Sporosarcina pasteurii, and a ureolytic bacterium isolated from sediments on the mine site were used to promote MICP. Removal of dissolved metals from the aqueous phase was determined via inductively coupled plasma mass spectrometry and resulting precipitates were analyzed via electron microscopy and energy dispersive x-ray spectroscopy (EDX). Both S. pasteurii and the native ureolytic isolate demonstrated ureolysis, increased the pH and promoted precipitation of CaCO3 in batch tests. MICP by the native bacterium reduced concentrations of the heavy metals zinc, copper, cadmium, nickel and manganese in the water. S. pasteurii was also able to promote MICP, but with less removal of dissolved metals. Analysis of precipitates revealed calcium carbonate and phosphate minerals were likely present. The native isolate is undergoing identification via 16S DNA sequencing. Ongoing work will evaluate biofilm formation and MICP by the isolate in continuous flow, gravel-filled laboratory columns. This research

  11. Study of heavy flavored particles

    International Nuclear Information System (INIS)

    1991-01-01

    This report discusses progress on the following topics: time-of- flight system; charmed baryon production and decays; D decays to baryons; measurement of sigma plus particles magnetic moments; and strong interaction coupling

  12. Weak decays of heavy quarks

    International Nuclear Information System (INIS)

    Gaillard, M.K.

    1978-08-01

    The properties that may help to identify the two additional quark flavors that are expected to be discovered. These properties are lifetime, branching ratios, selection rules, and lepton decay spectra. It is also noted that CP violation may manifest itself more strongly in heavy particle decays than elsewhere providing a new probe of its origin. The theoretical progress in the understanding of nonleptonic transitions among lighter quarks, nonleptonic K and hyperon decay amplitudes, omega minus and charmed particle decay predictions, and lastly the Kobayashi--Maskawa model for the weak coupling of heavy quarks together with the details of its implications for topology and bottomology are treated. 48 references

  13. Experimental studies of heavy-ion slowing down in matter

    International Nuclear Information System (INIS)

    Geissel, H.; Weick, H.; Scheidenberger, C.; Bimbot, R.; Gardes, D.

    2002-08-01

    Measurements of heavy-ion slowing down in matter differ in many aspects from experiments with light particles like protons and α-particles. An overview of the special experimental requirements, methods, data analysis and interpretation is presented for heavy-ion stopping powers, energy- and angular-straggling and ranges in the energy domain from keV/u up to GeV/u. Characteristic experimental results are presented and compared with theory and semiempirical predictions. New applications are outlined, which represent a challenge to continuously improve the knowledge of heavy-ion slowing down. (orig.)

  14. Toll-like receptors-2 and 4 are overexpressed in an experimental model of particle-induced osteolysis.

    Science.gov (United States)

    Valladares, Roberto D; Nich, Christophe; Zwingenberger, Stefan; Li, Chenguang; Swank, Katherine R; Gibon, Emmanuel; Rao, Allison J; Yao, Zhenyu; Goodman, Stuart B

    2014-09-01

    Aseptic loosening secondary to particle-associated periprosthetic osteolysis remains a major cause of failure of total joint replacements (TJR) in the mid- and long term. As sentinels of the innate immune system, macrophages are central to the recognition and initiation of the inflammatory cascade, which results in the activation of bone resorbing osteoclasts. Toll-like receptors (TLRs) are involved in the recognition of pathogen-associated molecular patterns and danger-associated molecular patterns. Experimentally, polymethylmethacrylate and polyethylene (PE) particles have been shown to activate macrophages via the TLR pathway. The specific TLRs involved in PE particle-induced osteolysis remain largely unknown. We hypothesized that TLR-2, -4, and -9 mediated responses play a critical role in the development of PE wear particle-induced osteolysis in the murine calvarium model. To test this hypothesis, we first demonstrated that PE particles caused observable osteolysis, visible by microCT and bone histomorphometry when the particles were applied to the calvarium of C57BL/6 mice. The number of TRAP positive osteoclasts was significantly greater in the PE-treated group when compared to the control group without particles. Finally, using immunohistochemistry, TLR-2 and TLR-4 were highly expressed in PE particle-induced osteolytic lesions, whereas TLR-9 was downregulated. TLR-2 and -4 may represent novel therapeutic targets for prevention of wear particle-induced osteolysis and accompanying TJR failure. © 2013 Wiley Periodicals, Inc.

  15. Heavy flavour production in 13 TeV pp collisions

    CERN Multimedia

    Braun, Svende Annelies

    2015-01-01

    This summer first data at the unprecedented energy of 13 TeV is collected at the LHC. This opens a new era in searches for new particles and precision tests of the Standard Model. Heavy flavour production plays an important role both as precision QCD test and as backgrounds for new particles. The first measurements of heavy flavour production are presented.

  16. Heavy ion and hadron reactions in emulsion

    International Nuclear Information System (INIS)

    Otterlund, I.

    1979-04-01

    Recent results from heavy ion and hadron reactions in emulsion are reviewed. General properties of hadron-reaction multiplicities and their correlation to the production of recoiling protons are given. Properties of pseudo-rapidity distributions of shower-particles especially the particle production in the central region of pseudo-rapidity will be discussed. Non-peripheral heavy ion reactions are compared to recent participant-spectator model calculations. Very energetic cosmic ray events will be examined in the light of recent results from hadron-nucleus reactions. (author)

  17. Elaboration by ion implantation of cobalt nano-particles in silica layers and modifications of their properties by electron and swift heavy ion irradiations; Elaboration par implantation ionique de nanoparticules de cobalt dans la silice et modifications de leurs proprietes sous irradiation d'electrons et d'ions de haute energie

    Energy Technology Data Exchange (ETDEWEB)

    D' Orleans, C

    2003-07-15

    This work aims to investigate the capability of ion irradiations to elaborate magnetic nano-particles in silica layers, and to modify their properties. Co{sup +} ions have been implanted at 160 keV at fluences of 2.10{sup 16}, 5.10{sup 16} and 10{sup 17} at/cm{sup 2}, and at temperatures of 77, 295 and 873 K. The dependence of the particle size on the implantation fluence, and more significantly on the implantation temperature has been shown. TEM (transmission electronic microscopy) observations have shown a mean diameter varying from 1 nm for implantations at 2.10{sup 16} Co{sup +}/cm{sup 2} at 77 K, to 9.7 nm at 10{sup 17} Co{sup +}/cm{sup 2} at 873 K. For high temperature implantations, two regions of particles appear. Simulations based on a kinetic 3-dimensional lattice Monte Carlo method reproduce quantitatively the features observed for implantations. Thermal treatments induce the ripening of the particles. Electron irradiations at 873 K induce an important increase in mean particle sizes. Swift heavy ion irradiations also induce the ripening of the particles for low fluences, and an elongation of the particles in the incident beam direction for high fluences, resulting in a magnetic anisotropy. Mechanisms invoked in thermal spike model could also explain this anisotropic growth. (author)

  18. Heavy-ion microbeam system at JAEA-Takasaki for microbeam biology

    International Nuclear Information System (INIS)

    Funayama, Tomoo; Wada, Seiichi; Yokota, Yuichiro

    2008-01-01

    Research concerning cellular responses to low dose irradiation, radiation-induced bystander effects, and the biological track structure of charged particles has recently received particular attention in the field of radiation biology. Target irradiation employing a microbeam represents a useful means of advancing this research by obviating some of the disadvantages associated with the conventional irradiation strategies. The heavy-ion microbeam system at Japan Atomic Energy Agency (JAEA)-Takasaki, which was planned in 1987 and started in the early 1990's, can provide target irradiation of heavy charged particles to biological material at atmospheric pressure using a minimum beam size 5 μm in diameter. A variety of biological material has been irradiated using this microbeam system including cultured mammalian and higher plant cells, isolated fibers of mouse skeletal muscle, silkworm (Bombyx mori) embryos and larvae, Arabidopsis thaliana roots, and the nematode Caenorhabditis elegans. The system can be applied to the investigation of mechanisms within biological organisms not only in the context of radiation biology, but also in the fields of general biology such as physiology, developmental biology and neurobiology, and should help to establish and contribute to the field of 'microbeam biology'. (author)

  19. Fragment formation in GeV-energy proton and light heavy-ion induced reactions

    International Nuclear Information System (INIS)

    Murakami, T.; Haga, M.; Haseno, M.

    2002-01-01

    We have investigated similarities and differences among the fragment formation processes in GeV-energy light-ion and light heavy-ion induced reactions. We have newly measured inclusive and exclusive energy spectra of intermediate mass fragments (3 ≤ Z ≤ 30; IMFs) for 8-GeV 16 O and 20 Ne and 12-GeV 20 Ne induced target multifragmentations (TMFs) in order to compare them with those previously measured for 8- and 12-GeV proton induced TMFs. We fond noticeable difference in their spectrum shapes and magnitudes but all of them clearly indicate the existence of sideward-peaked components, indicating fragment formations are mainly dictated not by a incident energy per nucleon but by a total energy of the projectile. (author)

  20. Trace metal analysis in sea grasses from Mexican Caribbean Coast by particle induced X-ray emission (PIXE)

    International Nuclear Information System (INIS)

    Solis, C.; Issac O, K.; Martinez, A.; Lavoisier, E.; Martinez, M. A.

    2008-01-01

    The growing urban and tourist activity in the Mexican Caribbean coasts has resulted in an increase of chemical substances, metals in particular, discharged to the coastal waters. In order to reach an adequate management and conservation of these marine ecosystems it is necessary to perform an inventory of the actual conditions that reflect the vulnerability and the level of damage. Sea-grasses are considered good biological indicators of heavy metal contamination in marine systems. The goal of this preliminary work is to evaluate the concentrations of trace metals such as Cr, Mn, Fe, Co, Cu, Zn, and Pb in Thalassia testudinum, a very common sea-grass in the Mexican Caribbean Sea. Samples were collected from several locations in the coasts of the Yucatan Peninsula: Holbox, Blanquizal and Punta Allen, areas virtually uninfluenced by anthropogenic activities. Trace elements in different part plants were determined by particle induced X-ray emission (PIXE). This is a very suitable technique since it offers a fast, accurate and multi-element analysis. Also, the analysis by PIXE can be performed directly on powdered leaves without a laborious sample preparation. The trace metal concentration determined in sea-grasses growing in Caribbean generally fall in the range of the lowest valuables reported for sea grasses from the Gulf of Mexico. The results indicate that the studied areas do not present contamination by heavy metals. (Author)

  1. Heavy accelerated nuclei in biomedical research

    International Nuclear Information System (INIS)

    Tobias, C.A.

    1987-01-01

    Accelerated atomic nuclei in physics accelerators have been used in basic biological research and in applied medical diagnostic and therapeutic studies for the past 50 years. The passage of single heavy particles through the cell nucleus is capable of producing multiple DNA double-strand scission and chromatin breaks. According to the Repair-Misrepair model, the high biological effectiveness of high-LET particles is due to misrepair and misrejoining of the breaks. The Bragg depth ionization effect allows heavy particles to deposit considerably more energy deep in tissue than at the surface, and this property has been used for great improvements in the radiation therapy of localized tumors. Recent advances in producing radioactive beams will allow verification of therapeutic administration of such beams. The radioactive beams also open a new field of Nuclear Medicine. There is increasing interest in building special biomedical light and heavy-ion accelerators. These will be used not only for therapy but also for diagnosis, for the study of radiation hazards in space flight, and for basic molecular and cellular understanding of the mechanisms of radiation effect

  2. Clinical results of stereotactic heavy-charged-particle radiosurgery for intracranial angiographically occult vascular malformations

    International Nuclear Information System (INIS)

    Levy, R.P.; Fabrikant, J.I.; Phillips, M.H.; Frankel, K.A.; Steinberg, G.K.; Marks, M.P.; DeLaPaz, R.L.; Chuang, F.Y.S.; Lyman, J.T.

    1989-12-01

    Angiographically occult vascular malformations (AOVMs) of the brain have been recognized for many years to cause neurologic morbidity and mortality. They generally become symptomatic due to intracranial hemorrhage, focal mass effect, seizures or headaches. The true incidence of AOVMs is unknown, but autopsy studies suggest that they are more common than high-flow angiographically demonstrable arteriovenous malformations (AVMs). We have developed stereotactic heavy-charged-particle Bragg peak radiosurgery for the treatment of inoperable intracranial vascular malformations, using the helium ion beams at the Lawrence Berkeley Laboratory 184-inch Synchrocyclotron and Bevatron. This report describes the protocol for patient selection, radiosurgical treatment planning method, clinical and neuroradiologic results and complications encountered, and discusses the strengths and limitations of the method. 10 refs., 1 fig

  3. Clinical results of stereotactic heavy-charged-particle radiosurgery for intracranial angiographically occult vascular malformations

    Energy Technology Data Exchange (ETDEWEB)

    Levy, R.P.; Fabrikant, J.I.; Phillips, M.H.; Frankel, K.A.; Steinberg, G.K.; Marks, M.P.; DeLaPaz, R.L.; Chuang, F.Y.S.; Lyman, J.T.

    1989-12-01

    Angiographically occult vascular malformations (AOVMs) of the brain have been recognized for many years to cause neurologic morbidity and mortality. They generally become symptomatic due to intracranial hemorrhage, focal mass effect, seizures or headaches. The true incidence of AOVMs is unknown, but autopsy studies suggest that they are more common than high-flow angiographically demonstrable arteriovenous malformations (AVMs). We have developed stereotactic heavy-charged-particle Bragg peak radiosurgery for the treatment of inoperable intracranial vascular malformations, using the helium ion beams at the Lawrence Berkeley Laboratory 184-inch Synchrocyclotron and Bevatron. This report describes the protocol for patient selection, radiosurgical treatment planning method, clinical and neuroradiologic results and complications encountered, and discusses the strengths and limitations of the method. 10 refs., 1 fig.

  4. Investigation of energetic particle induced geodesic acoustic mode

    Science.gov (United States)

    Schneller, Mirjam; Fu, Guoyong; Chavdarovski, Ilija; Wang, Weixing; Lauber, Philipp; Lu, Zhixin

    2017-10-01

    Energetic particles are ubiquitous in present and future tokamaks due to heating systems and fusion reactions. Anisotropy in the distribution function of the energetic particle population is able to excite oscillations from the continuous spectrum of geodesic acoustic modes (GAMs), which cannot be driven by plasma pressure gradients due to their toroidally and nearly poloidally symmetric structures. These oscillations are known as energetic particle-induced geodesic acoustic modes (EGAMs) [G.Y. Fu'08] and have been observed in recent experiments [R. Nazikian'08]. EGAMs are particularly attractive in the framework of turbulence regulation, since they lead to an oscillatory radial electric shear which can potentially saturate the turbulence. For the presented work, the nonlinear gyrokinetic, electrostatic, particle-in-cell code GTS [W.X. Wang'06] has been extended to include an energetic particle population following either bump-on-tail Maxwellian or slowing-down [Stix'76] distribution function. With this new tool, we study growth rate, frequency and mode structure of the EGAM in an ASDEX Upgrade-like scenario. A detailed understanding of EGAM excitation reveals essential for future studies of EGAM interaction with micro-turbulence. Funded by the Max Planck Princeton Research Center. Computational resources of MPCDF and NERSC are greatefully acknowledged.

  5. Bound states of a light atom and two heavy dipoles in two dimensions

    DEFF Research Database (Denmark)

    Rosa, D. S.; Bellotti, F. F.; Jensen, Aksel Stenholm

    2016-01-01

    We study a three-body system, formed by a light particle and two identical heavy dipoles, in two dimensions in the Born-Oppenheimer approximation. We present the analytic light-particle wave function resulting from an attractive zero-range potential between the light and each of the heavy particles...

  6. Monitoring of heavy metal particle emission in the exhaust duct of a foundry using LIBS

    International Nuclear Information System (INIS)

    Dutouquet, C.; Le Bihan, O.; Dermigny, A.; Frejafon, E.; Gallou, G.; Sirven, J.B.; Torralba, B.

    2014-01-01

    Heavy metals have long been known to be detrimental to human health and the environment.Their emission is mainly considered to occur via the atmospheric route. Most of airborne heavy metals are of anthropogenic origin and produced through combustion processes at industrial sites such as incinerators and foundries. Current regulations impose threshold limits on heavy metal emissions. The reference method currently implemented for quantitative measurements at exhaust stacks consists of on-site sampling of heavy metals on filters for the particulate phase (the most prominent and only fraction considered in this study) prior to subsequent laboratory analysis. Results are therefore known only a few days after sampling. Stiffer regulations require the development of adapted tools allowing automatic, on-site or even in-situ measurements with temporal resolutions. The Laser-Induced Breakdown Spectroscopy (LIBS) technique was deemed as a potential candidate to meet these requirements. On site experiments were run by melting copper bars and monitoring emission of this element in an exhaust duct at a pilot-scale furnace in a French research center dedicated to metal casting. Two approaches designated as indirect and direct analysis were broached in these experiments. The former corresponds to filter enrichment prior to subsequent LIBS interrogation whereas the latter entails laser focusing right through the aerosol for detection. On-site calibration curves were built and compared with those obtained at laboratory scale in order to investigate possible matrix and analyte effects. Eventually, the obtained results in terms of detection limits and quantitative temporal monitoring of copper emission clearly emphasize the potentialities of the direct LIBS measurements. (authors)

  7. Failla Memorial lecture. The future of heavy-ion science in biology and medicine.

    Science.gov (United States)

    Tobias, C A

    1985-07-01

    Interplanetary space contains fluxes of fast moving atomic nuclei. The distribution of these reflects the atomic composition of the universe, and such particles may pose limitations for space flight and for life in space. Over the past 50 years, since the invention of Ernest Lawrence's cyclotron, advances in accelerator technology have permitted the acceleration of charged nuclei to very high velocities. Currently, beams of any stable isotope species up to uranium are available at kinetic energies of several hundred MeV/nucleon at the Berkeley Bevalac. Recently, new areas of particle physics research relating to the mechanisms of spallation and fission have opened up for investigation, and it is now realistic to search for nuclear super-dense states that might be produced in heavy nuclear collisions. The heavy ions hold interest for a broad spectrum of research because of their effectiveness in producing a series of major lesions in DNA along single particle tracks and because of the Bragg depth ionization properties that allow the precise deposition of highly localized doses deep in the human body. Individual heavy ions can also interrupt the continuity of membraneous regions in cells. Heavy ions, when compared to low-LET radiation, have increased effectiveness for mammalian cell lethality, chromosome mutations, and cell transformation. The molecular mechanisms are not completely understood but appear to involve fragmentation and reintegration of DNA. Cells attempt to repair these lesions, and many of the deleterious effects are due to misrepair or misrejoining of DNA. Heavy ions do not require the presence of oxygen for producing their effects, and hypoxic cells in necrotic regions have nearly the same sensitivity as cells in well-oxygenated tissues. Heavy ions are effective in delaying or blocking the cell division process. Heavy ions are also strong enhancers of viral-induced cell transformation, a process that requires integration of foreign DNA. Some cell

  8. Search for heavy long-lived charged particles in pp collisions at $\\sqrt{s}$=7 TeV

    CERN Document Server

    Chatrchyan, Serguei; Sirunyan, Albert M; Tumasyan, Armen; Adam, Wolfgang; Bergauer, Thomas; Dragicevic, Marko; Erö, Janos; Fabjan, Christian; Friedl, Markus; Fruehwirth, Rudolf; Ghete, Vasile Mihai; Hammer, Josef; Hörmann, Natascha; Hrubec, Josef; Jeitler, Manfred; Kiesenhofer, Wolfgang; Knünz, Valentin; Krammer, Manfred; Liko, Dietrich; Mikulec, Ivan; Pernicka, Manfred; Rahbaran, Babak; Rohringer, Christine; Rohringer, Herbert; Schöfbeck, Robert; Strauss, Josef; Taurok, Anton; Teischinger, Florian; Wagner, Philipp; Waltenberger, Wolfgang; Walzel, Gerhard; Widl, Edmund; Wulz, Claudia-Elisabeth; Mossolov, Vladimir; Shumeiko, Nikolai; Suarez Gonzalez, Juan; Bansal, Sunil; Cerny, Karel; Cornelis, Tom; De Wolf, Eddi A; Janssen, Xavier; Luyckx, Sten; Maes, Thomas; Mucibello, Luca; Ochesanu, Silvia; Roland, Benoit; Rougny, Romain; Selvaggi, Michele; Van Haevermaet, Hans; Van Mechelen, Pierre; Van Remortel, Nick; Van Spilbeeck, Alex; Blekman, Freya; Blyweert, Stijn; D'Hondt, Jorgen; Gonzalez Suarez, Rebeca; Kalogeropoulos, Alexis; Maes, Michael; Olbrechts, Annik; Van Doninck, Walter; Van Mulders, Petra; Van Onsem, Gerrit Patrick; Villella, Ilaria; Charaf, Otman; Clerbaux, Barbara; De Lentdecker, Gilles; Dero, Vincent; Gay, Arnaud; Hreus, Tomas; Léonard, Alexandre; Marage, Pierre Edouard; Reis, Thomas; Thomas, Laurent; Vander Velde, Catherine; Vanlaer, Pascal; Adler, Volker; Beernaert, Kelly; Cimmino, Anna; Costantini, Silvia; Garcia, Guillaume; Grunewald, Martin; Klein, Benjamin; Lellouch, Jérémie; Marinov, Andrey; Mccartin, Joseph; Ocampo Rios, Alberto Andres; Ryckbosch, Dirk; Strobbe, Nadja; Thyssen, Filip; Tytgat, Michael; Vanelderen, Lukas; Verwilligen, Piet; Walsh, Sinead; Yazgan, Efe; Zaganidis, Nicolas; Basegmez, Suzan; Bruno, Giacomo; Ceard, Ludivine; Delaere, Christophe; Du Pree, Tristan; Favart, Denis; Forthomme, Laurent; Giammanco, Andrea; Hollar, Jonathan; Lemaitre, Vincent; Liao, Junhui; Militaru, Otilia; Nuttens, Claude; Pagano, Davide; Pin, Arnaud; Piotrzkowski, Krzysztof; Schul, Nicolas; Beliy, Nikita; Caebergs, Thierry; Daubie, Evelyne; Hammad, Gregory Habib; Alves, Gilvan; Correa Martins Junior, Marcos; De Jesus Damiao, Dilson; Martins, Thiago; Pol, Maria Elena; Henrique Gomes E Souza, Moacyr; Aldá Júnior, Walter Luiz; Carvalho, Wagner; Custódio, Analu; Melo Da Costa, Eliza; De Oliveira Martins, Carley; Fonseca De Souza, Sandro; Matos Figueiredo, Diego; Mundim, Luiz; Nogima, Helio; Oguri, Vitor; Prado Da Silva, Wanda Lucia; Santoro, Alberto; Silva Do Amaral, Sheila Mara; Soares Jorge, Luana; Sznajder, Andre; Souza Dos Anjos, Tiago; Bernardes, Cesar Augusto; De Almeida Dias, Flavia; Tomei, Thiago; De Moraes Gregores, Eduardo; Lagana, Caio; Da Cunha Marinho, Franciole; Mercadante, Pedro G; Novaes, Sergio F; Padula, Sandra; Genchev, Vladimir; Iaydjiev, Plamen; Piperov, Stefan; Rodozov, Mircho; Stoykova, Stefka; Sultanov, Georgi; Tcholakov, Vanio; Trayanov, Rumen; Vutova, Mariana; Dimitrov, Anton; Hadjiiska, Roumyana; Kozhuharov, Venelin; Litov, Leander; Pavlov, Borislav; Petkov, Peicho; Bian, Jian-Guo; Chen, Guo-Ming; Chen, He-Sheng; Jiang, Chun-Hua; Liang, Dong; Liang, Song; Meng, Xiangwei; Tao, Junquan; Wang, Jian; Wang, Jian; Wang, Xianyou; Wang, Zheng; Xiao, Hong; Xu, Ming; Zang, Jingjing; Zhang, Zhen; Asawatangtrakuldee, Chayanit; Ban, Yong; Guo, Shuang; Guo, Yifei; Li, Wenbo; Liu, Shuai; Mao, Yajun; Qian, Si-Jin; Teng, Haiyun; Wang, Siguang; Zhu, Bo; Zou, Wei; Avila, Carlos; Gomez Moreno, Bernardo; Osorio Oliveros, Andres Felipe; Sanabria, Juan Carlos; Godinovic, Nikola; Lelas, Damir; Plestina, Roko; Polic, Dunja; Puljak, Ivica; Antunovic, Zeljko; Dzelalija, Mile; Kovac, Marko; Brigljevic, Vuko; Duric, Senka; Kadija, Kreso; Luetic, Jelena; Morovic, Srecko; Attikis, Alexandros; Galanti, Mario; Mavromanolakis, Georgios; Mousa, Jehad; Nicolaou, Charalambos; Ptochos, Fotios; Razis, Panos A; Finger, Miroslav; Finger Jr, Michael; Assran, Yasser; Elgammal, Sherif; Ellithi Kamel, Ali; Khalil, Shaaban; Mahmoud, Mohammed; Radi, Amr; Kadastik, Mario; Müntel, Mait; Raidal, Martti; Rebane, Liis; Tiko, Andres; Azzolini, Virginia; Eerola, Paula; Fedi, Giacomo; Voutilainen, Mikko; Härkönen, Jaakko; Heikkinen, Mika Aatos; Karimäki, Veikko; Kinnunen, Ritva; Kortelainen, Matti J; Lampén, Tapio; Lassila-Perini, Kati; Lehti, Sami; Lindén, Tomas; Luukka, Panja-Riina; Mäenpää, Teppo; Peltola, Timo; Tuominen, Eija; Tuominiemi, Jorma; Tuovinen, Esa; Ungaro, Donatella; Wendland, Lauri; Banzuzi, Kukka; Korpela, Arja; Tuuva, Tuure; Besancon, Marc; Choudhury, Somnath; Dejardin, Marc; Denegri, Daniel; Fabbro, Bernard; Faure, Jean-Louis; Ferri, Federico; Ganjour, Serguei; Givernaud, Alain; Gras, Philippe; Hamel de Monchenault, Gautier; Jarry, Patrick; Locci, Elizabeth; Malcles, Julie; Millischer, Laurent; Nayak, Aruna; Rander, John; Rosowsky, André; Shreyber, Irina; Titov, Maksym; Baffioni, Stephanie; Beaudette, Florian; Benhabib, Lamia; Bianchini, Lorenzo; Bluj, Michal; Broutin, Clementine; Busson, Philippe; Charlot, Claude; Daci, Nadir; Dahms, Torsten; Dobrzynski, Ludwik; Granier de Cassagnac, Raphael; Haguenauer, Maurice; Miné, Philippe; Mironov, Camelia; Ochando, Christophe; Paganini, Pascal; Sabes, David; Salerno, Roberto; Sirois, Yves; Veelken, Christian; Zabi, Alexandre; Agram, Jean-Laurent; Andrea, Jeremy; Bloch, Daniel; Bodin, David; Brom, Jean-Marie; Cardaci, Marco; Chabert, Eric Christian; Collard, Caroline; Conte, Eric; Drouhin, Frédéric; Ferro, Cristina; Fontaine, Jean-Charles; Gelé, Denis; Goerlach, Ulrich; Juillot, Pierre; Karim, Mehdi; Le Bihan, Anne-Catherine; Van Hove, Pierre; Fassi, Farida; Mercier, Damien; Beauceron, Stephanie; Beaupere, Nicolas; Bondu, Olivier; Boudoul, Gaelle; Brun, Hugues; Chasserat, Julien; Chierici, Roberto; Contardo, Didier; Depasse, Pierre; El Mamouni, Houmani; Fay, Jean; Gascon, Susan; Gouzevitch, Maxime; Ille, Bernard; Kurca, Tibor; Lethuillier, Morgan; Mirabito, Laurent; Perries, Stephane; Sordini, Viola; Tosi, Silvano; Tschudi, Yohann; Verdier, Patrice; Viret, Sébastien; Tsamalaidze, Zviad; Anagnostou, Georgios; Beranek, Sarah; Edelhoff, Matthias; Feld, Lutz; Heracleous, Natalie; Hindrichs, Otto; Jussen, Ruediger; Klein, Katja; Merz, Jennifer; Ostapchuk, Andrey; Perieanu, Adrian; Raupach, Frank; Sammet, Jan; Schael, Stefan; Sprenger, Daniel; Weber, Hendrik; Wittmer, Bruno; Zhukov, Valery; Ata, Metin; Caudron, Julien; Dietz-Laursonn, Erik; Duchardt, Deborah; Erdmann, Martin; Güth, Andreas; Hebbeker, Thomas; Heidemann, Carsten; Hoepfner, Kerstin; Klimkovich, Tatsiana; Klingebiel, Dennis; Kreuzer, Peter; Lanske, Dankfried; Lingemann, Joschka; Magass, Carsten; Merschmeyer, Markus; Meyer, Arnd; Olschewski, Mark; Papacz, Paul; Pieta, Holger; Reithler, Hans; Schmitz, Stefan Antonius; Sonnenschein, Lars; Steggemann, Jan; Teyssier, Daniel; Weber, Martin; Bontenackels, Michael; Cherepanov, Vladimir; Davids, Martina; Flügge, Günter; Geenen, Heiko; Geisler, Matthias; Haj Ahmad, Wael; Hoehle, Felix; Kargoll, Bastian; Kress, Thomas; Kuessel, Yvonne; Linn, Alexander; Nowack, Andreas; Perchalla, Lars; Pooth, Oliver; Rennefeld, Jörg; Sauerland, Philip; Stahl, Achim; Aldaya Martin, Maria; Behr, Joerg; Behrenhoff, Wolf; Behrens, Ulf; Bergholz, Matthias; Bethani, Agni; Borras, Kerstin; Burgmeier, Armin; Cakir, Altan; Calligaris, Luigi; Campbell, Alan; Castro, Elena; Costanza, Francesco; Dammann, Dirk; Eckerlin, Guenter; Eckstein, Doris; Fischer, David; Flucke, Gero; Geiser, Achim; Glushkov, Ivan; Habib, Shiraz; Hauk, Johannes; Jung, Hannes; Kasemann, Matthias; Katsas, Panagiotis; Kleinwort, Claus; Kluge, Hannelies; Knutsson, Albert; Krämer, Mira; Krücker, Dirk; Kuznetsova, Ekaterina; Lange, Wolfgang; Lohmann, Wolfgang; Lutz, Benjamin; Mankel, Rainer; Marfin, Ihar; Marienfeld, Markus; Melzer-Pellmann, Isabell-Alissandra; Meyer, Andreas Bernhard; Mnich, Joachim; Mussgiller, Andreas; Naumann-Emme, Sebastian; Olzem, Jan; Perrey, Hanno; Petrukhin, Alexey; Pitzl, Daniel; Raspereza, Alexei; Ribeiro Cipriano, Pedro M; Riedl, Caroline; Rosin, Michele; Salfeld-Nebgen, Jakob; Schmidt, Ringo; Schoerner-Sadenius, Thomas; Sen, Niladri; Spiridonov, Alexander; Stein, Matthias; Walsh, Roberval; Wissing, Christoph; Autermann, Christian; Blobel, Volker; Bobrovskyi, Sergei; Draeger, Jula; Enderle, Holger; Erfle, Joachim; Gebbert, Ulla; Görner, Martin; Hermanns, Thomas; Höing, Rebekka Sophie; Kaschube, Kolja; Kaussen, Gordon; Kirschenmann, Henning; Klanner, Robert; Lange, Jörn; Mura, Benedikt; Nowak, Friederike; Pietsch, Niklas; Rathjens, Denis; Sander, Christian; Schettler, Hannes; Schleper, Peter; Schlieckau, Eike; Schmidt, Alexander; Schröder, Matthias; Schum, Torben; Seidel, Markus; Stadie, Hartmut; Steinbrück, Georg; Thomsen, Jan; Barth, Christian; Berger, Joram; Chwalek, Thorsten; De Boer, Wim; Dierlamm, Alexander; Feindt, Michael; Guthoff, Moritz; Hackstein, Christoph; Hartmann, Frank; Heinrich, Michael; Held, Hauke; Hoffmann, Karl-Heinz; Honc, Simon; Katkov, Igor; Komaragiri, Jyothsna Rani; Martschei, Daniel; Mueller, Steffen; Müller, Thomas; Niegel, Martin; Nürnberg, Andreas; Oberst, Oliver; Oehler, Andreas; Ott, Jochen; Peiffer, Thomas; Quast, Gunter; Rabbertz, Klaus; Ratnikov, Fedor; Ratnikova, Natalia; Röcker, Steffen; Saout, Christophe; Scheurer, Armin; Schilling, Frank-Peter; Schmanau, Mike; Schott, Gregory; Simonis, Hans-Jürgen; Stober, Fred-Markus Helmut; Troendle, Daniel; Ulrich, Ralf; Wagner-Kuhr, Jeannine; Weiler, Thomas; Zeise, Manuel; Ziebarth, Eva Barbara; Daskalakis, Georgios; Geralis, Theodoros; Kesisoglou, Stilianos; Kyriakis, Aristotelis; Loukas, Demetrios; Manolakos, Ioannis; Markou, Athanasios; Markou, Christos; Mavrommatis, Charalampos; Ntomari, Eleni; Gouskos, Loukas; Mertzimekis, Theodoros; Panagiotou, Apostolos; Saoulidou, Niki; Evangelou, Ioannis; Foudas, Costas; Kokkas, Panagiotis; Manthos, Nikolaos; Papadopoulos, Ioannis; Patras, Vaios; Bencze, Gyorgy; Hajdu, Csaba; Hidas, Pàl; Horvath, Dezso; Krajczar, Krisztian; Radics, Balint; Sikler, Ferenc; Veszpremi, Viktor; Vesztergombi, Gyorgy; Beni, Noemi; Czellar, Sandor; Molnar, Jozsef; Palinkas, Jozsef; Szillasi, Zoltan; Karancsi, János; Raics, Peter; Trocsanyi, Zoltan Laszlo; Ujvari, Balazs; Beri, Suman Bala; Bhatnagar, Vipin; Dhingra, Nitish; Gupta, Ruchi; Jindal, Monika; Kaur, Manjit; Kohli, Jatinder Mohan; Mehta, Manuk Zubin; Nishu, Nishu; Saini, Lovedeep Kaur; Sharma, Archana; Singh, Jasbir; Singh, Supreet Pal; Ahuja, Sudha; Bhardwaj, Ashutosh; Choudhary, Brajesh C; Kumar, Ashok; Kumar, Arun; Malhotra, Shivali; Naimuddin, Md; Ranjan, Kirti; Sharma, Varun; Shivpuri, Ram Krishen; Banerjee, Sunanda; Bhattacharya, Satyaki; Dutta, Suchandra; Gomber, Bhawna; Jain, Sandhya; Jain, Shilpi; Khurana, Raman; Sarkar, Subir; Abdulsalam, Abdulla; Choudhury, Rajani Kant; Dutta, Dipanwita; Kailas, Swaminathan; Kumar, Vineet; Mohanty, Ajit Kumar; Pant, Lalit Mohan; Shukla, Prashant; Aziz, Tariq; Ganguly, Sanmay; Guchait, Monoranjan; Gurtu, Atul; Maity, Manas; Majumder, Gobinda; Mazumdar, Kajari; Mohanty, Gagan Bihari; Parida, Bibhuti; Sudhakar, Katta; Wickramage, Nadeesha; Banerjee, Sudeshna; Dugad, Shashikant; Arfaei, Hessamaddin; Bakhshiansohi, Hamed; Etesami, Seyed Mohsen; Fahim, Ali; Hashemi, Majid; Hesari, Hoda; Jafari, Abideh; Khakzad, Mohsen; Mohammadi, Abdollah; Mohammadi Najafabadi, Mojtaba; Paktinat Mehdiabadi, Saeid; Safarzadeh, Batool; Zeinali, Maryam; Abbrescia, Marcello; Barbone, Lucia; Calabria, Cesare; Chhibra, Simranjit Singh; Colaleo, Anna; Creanza, Donato; De Filippis, Nicola; De Palma, Mauro; Fiore, Luigi; Iaselli, Giuseppe; Lusito, Letizia; Maggi, Giorgio; Maggi, Marcello; Marangelli, Bartolomeo; My, Salvatore; Nuzzo, Salvatore; Pacifico, Nicola; Pompili, Alexis; Pugliese, Gabriella; Selvaggi, Giovanna; Silvestris, Lucia; Singh, Gurpreet; Zito, Giuseppe; Abbiendi, Giovanni; Benvenuti, Alberto; Bonacorsi, Daniele; Braibant-Giacomelli, Sylvie; Brigliadori, Luca; Capiluppi, Paolo; Castro, Andrea; Cavallo, Francesca Romana; Cuffiani, Marco; Dallavalle, Gaetano-Marco; Fabbri, Fabrizio; Fanfani, Alessandra; Fasanella, Daniele; Giacomelli, Paolo; Grandi, Claudio; Guiducci, Luigi; Marcellini, Stefano; Masetti, Gianni; Meneghelli, Marco; Montanari, Alessandro; Navarria, Francesco; Odorici, Fabrizio; Perrotta, Andrea; Primavera, Federica; Rossi, Antonio; Rovelli, Tiziano; Siroli, Gianni; Travaglini, Riccardo; Albergo, Sebastiano; Cappello, Gigi; Chiorboli, Massimiliano; Costa, Salvatore; Potenza, Renato; Tricomi, Alessia; Tuve, Cristina; Barbagli, Giuseppe; Ciulli, Vitaliano; Civinini, Carlo; D'Alessandro, Raffaello; Focardi, Ettore; Frosali, Simone; Gallo, Elisabetta; Gonzi, Sandro; Meschini, Marco; Paoletti, Simone; Sguazzoni, Giacomo; Tropiano, Antonio; Benussi, Luigi; Bianco, Stefano; Colafranceschi, Stefano; Fabbri, Franco; Piccolo, Davide; Fabbricatore, Pasquale; Musenich, Riccardo; Benaglia, Andrea; De Guio, Federico; Di Matteo, Leonardo; Fiorendi, Sara; Gennai, Simone; Ghezzi, Alessio; Malvezzi, Sandra; Manzoni, Riccardo Andrea; Martelli, Arabella; Massironi, Andrea; Menasce, Dario; Moroni, Luigi; Paganoni, Marco; Pedrini, Daniele; Ragazzi, Stefano; Redaelli, Nicola; Sala, Silvano; Tabarelli de Fatis, Tommaso; Buontempo, Salvatore; Carrillo Montoya, Camilo Andres; Cavallo, Nicola; De Cosa, Annapaola; Dogangun, Oktay; Fabozzi, Francesco; Iorio, Alberto Orso Maria; Lista, Luca; Meola, Sabino; Merola, Mario; Paolucci, Pierluigi; Azzi, Patrizia; Bacchetta, Nicola; Bellan, Paolo; Bisello, Dario; Branca, Antonio; Carlin, Roberto; Checchia, Paolo; Dorigo, Tommaso; Gasparini, Fabrizio; Gasparini, Ugo; Gozzelino, Andrea; Kanishchev, Konstantin; Lacaprara, Stefano; Lazzizzera, Ignazio; Margoni, Martino; Meneguzzo, Anna Teresa; Nespolo, Massimo; Perrozzi, Luca; Pozzobon, Nicola; Ronchese, Paolo; Simonetto, Franco; Torassa, Ezio; Tosi, Mia; Vanini, Sara; Zotto, Pierluigi; Gabusi, Michele; Ratti, Sergio P; Riccardi, Cristina; Torre, Paola; Vitulo, Paolo; Bilei, Gian Mario; Fanò, Livio; Lariccia, Paolo; Lucaroni, Andrea; Mantovani, Giancarlo; Menichelli, Mauro; Nappi, Aniello; Romeo, Francesco; Saha, Anirban; Santocchia, Attilio; Taroni, Silvia; Azzurri, Paolo; Bagliesi, Giuseppe; Boccali, Tommaso; Broccolo, Giuseppe; Castaldi, Rino; D'Agnolo, Raffaele Tito; Dell'Orso, Roberto; Fiori, Francesco; Foà, Lorenzo; Giassi, Alessandro; Kraan, Aafke; Ligabue, Franco; Lomtadze, Teimuraz; Martini, Luca; Messineo, Alberto; Palla, Fabrizio; Palmonari, Francesco; Rizzi, Andrea; Serban, Alin Titus; Spagnolo, Paolo; Squillacioti, Paola; Tenchini, Roberto; Tonelli, Guido; Venturi, Andrea; Verdini, Piero Giorgio; Barone, Luciano; Cavallari, Francesca; Del Re, Daniele; Diemoz, Marcella; Fanelli, Cristiano; Grassi, Marco; Longo, Egidio; Meridiani, Paolo; Micheli, Francesco; Nourbakhsh, Shervin; Organtini, Giovanni; Pandolfi, Francesco; Paramatti, Riccardo; Rahatlou, Shahram; Sigamani, Michael; Soffi, Livia; Amapane, Nicola; Arcidiacono, Roberta; Argiro, Stefano; Arneodo, Michele; Biino, Cristina; Botta, Cristina; Cartiglia, Nicolo; Castello, Roberto; Costa, Marco; Dellacasa, Giulio; Demaria, Natale; Graziano, Alberto; Mariotti, Chiara; Maselli, Silvia; Migliore, Ernesto; Monaco, Vincenzo; Musich, Marco; Obertino, Maria Margherita; Pastrone, Nadia; Pelliccioni, Mario; Potenza, Alberto; Romero, Alessandra; Ruspa, Marta; Sacchi, Roberto; Solano, Ada; Staiano, Amedeo; Vilela Pereira, Antonio; Belforte, Stefano; Cossutti, Fabio; Della Ricca, Giuseppe; Gobbo, Benigno; Marone, Matteo; Montanino, Damiana; Penzo, Aldo; Schizzi, Andrea; Heo, Seong Gu; Kim, Tae Yeon; Nam, Soon-Kwon; Chang, Sunghyun; Chung, Jin Hyuk; Kim, Dong Hee; Kim, Gui Nyun; Kong, Dae Jung; Park, Hyangkyu; Ro, Sang-Ryul; Son, Dong-Chul; Son, Taejin; Kim, Jae Yool; Kim, Zero Jaeho; Song, Sanghyeon; Jo, Hyun Yong; Choi, Suyong; Gyun, Dooyeon; Hong, Byung-Sik; Jo, Mihee; Kim, Hyunchul; Kim, Tae Jeong; Lee, Kyong Sei; Moon, Dong Ho; Park, Sung Keun; Seo, Eunsung; Choi, Minkyoo; Kang, Seokon; Kim, Hyunyong; Kim, Ji Hyun; Park, Chawon; Park, Inkyu; Park, Sangnam; Ryu, Geonmo; Cho, Yongjin; Choi, Young-Il; Choi, Young Kyu; Goh, Junghwan; Kim, Min Suk; Kwon, Eunhyang; Lee, Byounghoon; Lee, Jongseok; Lee, Sungeun; Seo, Hyunkwan; Yu, Intae; Bilinskas, Mykolas Jurgis; Grigelionis, Ignas; Janulis, Mindaugas; Juodagalvis, Andrius; Castilla-Valdez, Heriberto; De La Cruz-Burelo, Eduard; Heredia-de La Cruz, Ivan; Lopez-Fernandez, Ricardo; Magaña Villalba, Ricardo; Martínez-Ortega, Jorge; Sánchez-Hernández, Alberto; Villasenor-Cendejas, Luis Manuel; Carrillo Moreno, Salvador; Vazquez Valencia, Fabiola; Salazar Ibarguen, Humberto Antonio; Casimiro Linares, Edgar; Morelos Pineda, Antonio; Reyes-Santos, Marco A; Krofcheck, David; Bell, Alan James; Butler, Philip H; Doesburg, Robert; Reucroft, Steve; Silverwood, Hamish; Ahmad, Muhammad; Asghar, Muhammad Irfan; Hoorani, Hafeez R; Khalid, Shoaib; Khan, Wajid Ali; Khurshid, Taimoor; Qazi, Shamona; Shah, Mehar Ali; Shoaib, Muhammad; Brona, Grzegorz; Bunkowski, Karol; Cwiok, Mikolaj; Dominik, Wojciech; Doroba, Krzysztof; Kalinowski, Artur; Konecki, Marcin; Krolikowski, Jan; Bialkowska, Helena; Boimska, Bozena; Frueboes, Tomasz; Gokieli, Ryszard; Górski, Maciej; Kazana, Malgorzata; Nawrocki, Krzysztof; Romanowska-Rybinska, Katarzyna; Szleper, Michal; Wrochna, Grzegorz; Zalewski, Piotr; Almeida, Nuno; Bargassa, Pedrame; David Tinoco Mendes, Andre; Faccioli, Pietro; Ferreira Parracho, Pedro Guilherme; Gallinaro, Michele; Musella, Pasquale; Seixas, Joao; Varela, Joao; Vischia, Pietro; Belotelov, Ivan; Bunin, Pavel; Gavrilenko, Mikhail; Golutvin, Igor; Kamenev, Alexey; Karjavin, Vladimir; Kozlov, Guennady; Lanev, Alexander; Malakhov, Alexander; Moisenz, Petr; Palichik, Vladimir; Perelygin, Victor; Savina, Maria; Shmatov, Sergey; Smirnov, Vitaly; Volodko, Anton; Zarubin, Anatoli; Evstyukhin, Sergey; Golovtsov, Victor; Ivanov, Yury; Kim, Victor; Levchenko, Petr; Murzin, Victor; Oreshkin, Vadim; Smirnov, Igor; Sulimov, Valentin; Uvarov, Lev; Vavilov, Sergey; Vorobyev, Alexey; Vorobyev, Andrey; Andreev, Yuri; Dermenev, Alexander; Gninenko, Sergei; Golubev, Nikolai; Kirsanov, Mikhail; Krasnikov, Nikolai; Matveev, Viktor; Pashenkov, Anatoli; Tlisov, Danila; Toropin, Alexander; Epshteyn, Vladimir; Erofeeva, Maria; Gavrilov, Vladimir; Kossov, Mikhail; Lychkovskaya, Natalia; Popov, Vladimir; Safronov, Grigory; Semenov, Sergey; Stolin, Viatcheslav; Vlasov, Evgueni; Zhokin, Alexander; Belyaev, Andrey; Boos, Edouard; Dubinin, Mikhail; Dudko, Lev; Ershov, Alexander; Gribushin, Andrey; Klyukhin, Vyacheslav; Kodolova, Olga; Lokhtin, Igor; Markina, Anastasia; Obraztsov, Stepan; Perfilov, Maxim; Petrushanko, Sergey; Popov, Andrey; Sarycheva, Ludmila; Savrin, Viktor; Snigirev, Alexander; Andreev, Vladimir; Azarkin, Maksim; Dremin, Igor; Kirakosyan, Martin; Leonidov, Andrey; Mesyats, Gennady; Rusakov, Sergey V; Vinogradov, Alexey; Azhgirey, Igor; Bayshev, Igor; Bitioukov, Sergei; Grishin, Viatcheslav; Kachanov, Vassili; Konstantinov, Dmitri; Korablev, Andrey; Krychkine, Victor; Petrov, Vladimir; Ryutin, Roman; Sobol, Andrei; Tourtchanovitch, Leonid; Troshin, Sergey; Tyurin, Nikolay; Uzunian, Andrey; Volkov, Alexey; Adzic, Petar; Djordjevic, Milos; Ekmedzic, Marko; Krpic, Dragomir; Milosevic, Jovan; Aguilar-Benitez, Manuel; Alcaraz Maestre, Juan; Arce, Pedro; Battilana, Carlo; Calvo, Enrique; Cerrada, Marcos; Chamizo Llatas, Maria; Colino, Nicanor; De La Cruz, Begona; Delgado Peris, Antonio; Diez Pardos, Carmen; Domínguez Vázquez, Daniel; Fernandez Bedoya, Cristina; Fernández Ramos, Juan Pablo; Ferrando, Antonio; Flix, Jose; Fouz, Maria Cruz; Garcia-Abia, Pablo; Gonzalez Lopez, Oscar; Goy Lopez, Silvia; Hernandez, Jose M; Josa, Maria Isabel; Merino, Gonzalo; Puerta Pelayo, Jesus; Redondo, Ignacio; Romero, Luciano; Santaolalla, Javier; Senghi Soares, Mara; Willmott, Carlos; Albajar, Carmen; Codispoti, Giuseppe; de Trocóniz, Jorge F; Cuevas, Javier; Fernandez Menendez, Javier; Folgueras, Santiago; Gonzalez Caballero, Isidro; Lloret Iglesias, Lara; Piedra Gomez, Jonatan; Vizan Garcia, Jesus Manuel; Brochero Cifuentes, Javier Andres; Cabrillo, Iban Jose; Calderon, Alicia; Chuang, Shan-Huei; Duarte Campderros, Jordi; Felcini, Marta; Fernandez, Marcos; Gomez, Gervasio; Gonzalez Sanchez, Javier; Jorda, Clara; Lobelle Pardo, Patricia; Lopez Virto, Amparo; Marco, Jesus; Marco, Rafael; Martinez Rivero, Celso; Matorras, Francisco; Munoz Sanchez, Francisca Javiela; Rodrigo, Teresa; Rodríguez-Marrero, Ana Yaiza; Ruiz-Jimeno, Alberto; Scodellaro, Luca; Sobron Sanudo, Mar; Vila, Ivan; Vilar Cortabitarte, Rocio; Abbaneo, Duccio; Auffray, Etiennette; Auzinger, Georg; Baillon, Paul; Ball, Austin; Barney, David; Bernet, Colin; Bianchi, Giovanni; Bloch, Philippe; Bocci, Andrea; Bonato, Alessio; Breuker, Horst; Camporesi, Tiziano; Cerminara, Gianluca; Christiansen, Tim; Coarasa Perez, Jose Antonio; D'Enterria, David; De Roeck, Albert; Di Guida, Salvatore; Dobson, Marc; Dupont-Sagorin, Niels; Elliott-Peisert, Anna; Frisch, Benjamin; Funk, Wolfgang; Georgiou, Georgios; Giffels, Manuel; Gigi, Dominique; Gill, Karl; Giordano, Domenico; Giunta, Marina; Glege, Frank; Gomez-Reino Garrido, Robert; Govoni, Pietro; Gowdy, Stephen; Guida, Roberto; Hansen, Magnus; Harris, Philip; Hartl, Christian; Harvey, John; Hegner, Benedikt; Hinzmann, Andreas; Innocente, Vincenzo; Janot, Patrick; Kaadze, Ketino; Karavakis, Edward; Kousouris, Konstantinos; Lecoq, Paul; Lenzi, Piergiulio; Lourenco, Carlos; Maki, Tuula; Malberti, Martina; Malgeri, Luca; Mannelli, Marcello; Masetti, Lorenzo; Meijers, Frans; Mersi, Stefano; Meschi, Emilio; Moser, Roland; Mozer, Matthias Ulrich; Mulders, Martijn; Nesvold, Erik; Nguyen, Matthew; Orimoto, Toyoko; Orsini, Luciano; Palencia Cortezon, Enrique; Perez, Emmanuelle; Petrilli, Achille; Pfeiffer, Andreas; Pierini, Maurizio; Pimiä, Martti; Piparo, Danilo; Polese, Giovanni; Quertenmont, Loic; Racz, Attila; Reece, William; Rodrigues Antunes, Joao; Rolandi, Gigi; Rommerskirchen, Tanja; Rovelli, Chiara; Rovere, Marco; Sakulin, Hannes; Santanastasio, Francesco; Schäfer, Christoph; Schwick, Christoph; Segoni, Ilaria; Sekmen, Sezen; Sharma, Archana; Siegrist, Patrice; Silva, Pedro; Simon, Michal; Sphicas, Paraskevas; Spiga, Daniele; Spiropulu, Maria; Stoye, Markus; Tsirou, Andromachi; Veres, Gabor Istvan; Vlimant, Jean-Roch; Wöhri, Hermine Katharina; Worm, Steven; Zeuner, Wolfram Dietrich; Bertl, Willi; Deiters, Konrad; Erdmann, Wolfram; Gabathuler, Kurt; Horisberger, Roland; Ingram, Quentin; Kaestli, Hans-Christian; König, Stefan; Kotlinski, Danek; Langenegger, Urs; Meier, Frank; Renker, Dieter; Rohe, Tilman; Sibille, Jennifer; Bäni, Lukas; Bortignon, Pierluigi; Buchmann, Marco-Andrea; Casal, Bruno; Chanon, Nicolas; Chen, Zhiling; Deisher, Amanda; Dissertori, Günther; Dittmar, Michael; Dünser, Marc; Eugster, Jürg; Freudenreich, Klaus; Grab, Christoph; Lecomte, Pierre; Lustermann, Werner; Marini, Andrea Carlo; Martinez Ruiz del Arbol, Pablo; Mohr, Niklas; Moortgat, Filip; Nägeli, Christoph; Nef, Pascal; Nessi-Tedaldi, Francesca; Pape, Luc; Pauss, Felicitas; Peruzzi, Marco; Ronga, Frederic Jean; Rossini, Marco; Sala, Leonardo; Sanchez, Ann - Karin; Starodumov, Andrei; Stieger, Benjamin; Takahashi, Maiko; Tauscher, Ludwig; Thea, Alessandro; Theofilatos, Konstantinos; Treille, Daniel; Urscheler, Christina; Wallny, Rainer; Weber, Hannsjoerg Artur; Wehrli, Lukas; Aguilo, Ernest; Amsler, Claude; Chiochia, Vincenzo; De Visscher, Simon; Favaro, Carlotta; Ivova Rikova, Mirena; Millan Mejias, Barbara; Otiougova, Polina; Robmann, Peter; Snoek, Hella; Tupputi, Salvatore; Verzetti, Mauro; Chang, Yuan-Hann; Chen, Kuan-Hsin; Go, Apollo; Kuo, Chia-Ming; Li, Syue-Wei; Lin, Willis; Liu, Zong-Kai; Lu, Yun-Ju; Mekterovic, Darko; Singh, Anil; Volpe, Roberta; Yu, Shin-Shan; Bartalini, Paolo; Chang, Paoti; Chang, You-Hao; Chang, Yu-Wei; Chao, Yuan; Chen, Kai-Feng; Dietz, Charles; Grundler, Ulysses; Hou, George Wei-Shu; Hsiung, Yee; Kao, Kai-Yi; Lei, Yeong-Jyi; Lu, Rong-Shyang; Majumder, Devdatta; Petrakou, Eleni; Shi, Xin; Shiu, Jing-Ge; Tzeng, Yeng-Ming; Wang, Minzu; Adiguzel, Aytul; Bakirci, Mustafa Numan; Cerci, Salim; Dozen, Candan; Dumanoglu, Isa; Eskut, Eda; Girgis, Semiray; Gokbulut, Gul; Hos, Ilknur; Kangal, Evrim Ersin; Karapinar, Guler; Kayis Topaksu, Aysel; Onengut, Gulsen; Ozdemir, Kadri; Ozturk, Sertac; Polatoz, Ayse; Sogut, Kenan; Sunar Cerci, Deniz; Tali, Bayram; Topakli, Huseyin; Vergili, Latife Nukhet; Vergili, Mehmet; Akin, Ilina Vasileva; Aliev, Takhmasib; Bilin, Bugra; Bilmis, Selcuk; Deniz, Muhammed; Gamsizkan, Halil; Guler, Ali Murat; Ocalan, Kadir; Ozpineci, Altug; Serin, Meltem; Sever, Ramazan; Surat, Ugur Emrah; Yalvac, Metin; Yildirim, Eda; Zeyrek, Mehmet; Deliomeroglu, Mehmet; Gülmez, Erhan; Isildak, Bora; Kaya, Mithat; Kaya, Ozlem; Ozkorucuklu, Suat; Sonmez, Nasuf; Cankocak, Kerem; Levchuk, Leonid; Bostock, Francis; Brooke, James John; Clement, Emyr; Cussans, David; Flacher, Henning; Frazier, Robert; Goldstein, Joel; Grimes, Mark; Heath, Greg P; Heath, Helen F; Kreczko, Lukasz; Metson, Simon; Newbold, Dave M; Nirunpong, Kachanon; Poll, Anthony; Senkin, Sergey; Smith, Vincent J; Williams, Thomas; Basso, Lorenzo; Bell, Ken W; Belyaev, Alexander; Brew, Christopher; Brown, Robert M; Cockerill, David JA; Coughlan, John A; Harder, Kristian; Harper, Sam; Jackson, James; Kennedy, Bruce W; Olaiya, Emmanuel; Petyt, David; Radburn-Smith, Benjamin Charles; Shepherd-Themistocleous, Claire; Tomalin, Ian R; Womersley, William John; Bainbridge, Robert; Ball, Gordon; Beuselinck, Raymond; Buchmuller, Oliver; Colling, David; Cripps, Nicholas; Cutajar, Michael; Dauncey, Paul; Davies, Gavin; Della Negra, Michel; Ferguson, William; Fulcher, Jonathan; Futyan, David; Gilbert, Andrew; Guneratne Bryer, Arlo; Hall, Geoffrey; Hatherell, Zoe; Hays, Jonathan; Iles, Gregory; Jarvis, Martyn; Karapostoli, Georgia; Lyons, Louis; Magnan, Anne-Marie; Marrouche, Jad; Mathias, Bryn; Nandi, Robin; Nash, Jordan; Nikitenko, Alexander; Papageorgiou, Anastasios; Pela, Joao; Pesaresi, Mark; Petridis, Konstantinos; Pioppi, Michele; Raymond, David Mark; Rogerson, Samuel; Rompotis, Nikolaos; Rose, Andrew; Ryan, Matthew John; Seez, Christopher; Sharp, Peter; Sparrow, Alex; Tapper, Alexander; Vazquez Acosta, Monica; Virdee, Tejinder; Wakefield, Stuart; Wardle, Nicholas; Whyntie, Tom; Barrett, Matthew; Chadwick, Matthew; Cole, Joanne; Hobson, Peter R; Khan, Akram; Kyberd, Paul; Leggat, Duncan; Leslie, Dawn; Martin, William; Reid, Ivan; Symonds, Philip; Teodorescu, Liliana; Turner, Mark; Hatakeyama, Kenichi; Liu, Hongxuan; Scarborough, Tara; Henderson, Conor; Rumerio, Paolo; Avetisyan, Aram; Bose, Tulika; Fantasia, Cory; Heister, Arno; St John, Jason; Lawson, Philip; Lazic, Dragoslav; Rohlf, James; Sperka, David; Sulak, Lawrence; Alimena, Juliette; Bhattacharya, Saptaparna; Cutts, David; Ferapontov, Alexey; Heintz, Ulrich; Jabeen, Shabnam; Kukartsev, Gennadiy; Landsberg, Greg; Luk, Michael; Narain, Meenakshi; Nguyen, Duong; Segala, Michael; Sinthuprasith, Tutanon; Speer, Thomas; Tsang, Ka Vang; Breedon, Richard; Breto, Guillermo; Calderon De La Barca Sanchez, Manuel; Chauhan, Sushil; Chertok, Maxwell; Conway, John; Conway, Rylan; Cox, Peter Timothy; Dolen, James; Erbacher, Robin; Gardner, Michael; Houtz, Rachel; Ko, Winston; Kopecky, Alexandra; Lander, Richard; Mall, Orpheus; Miceli, Tia; Nelson, Randy; Pellett, Dave; Rutherford, Britney; Searle, Matthew; Smith, John; Squires, Michael; Tripathi, Mani; Vasquez Sierra, Ricardo; Andreev, Valeri; Cline, David; Cousins, Robert; Duris, Joseph; Erhan, Samim; Everaerts, Pieter; Farrell, Chris; Hauser, Jay; Ignatenko, Mikhail; Plager, Charles; Rakness, Gregory; Schlein, Peter; Tucker, Jordan; Valuev, Vyacheslav; Weber, Matthias; Babb, John; Clare, Robert; Dinardo, Mauro Emanuele; Ellison, John Anthony; Gary, J William; Giordano, Ferdinando; Hanson, Gail; Jeng, Geng-Yuan; Liu, Hongliang; Long, Owen Rosser; Luthra, Arun; Nguyen, Harold; Paramesvaran, Sudarshan; Sturdy, Jared; Sumowidagdo, Suharyo; Wilken, Rachel; Wimpenny, Stephen; Andrews, Warren; Branson, James G; Cerati, Giuseppe Benedetto; Cittolin, Sergio; Evans, David; Golf, Frank; Holzner, André; Kelley, Ryan; Lebourgeois, Matthew; Letts, James; Macneill, Ian; Mangano, Boris; Muelmenstaedt, Johannes; Padhi, Sanjay; Palmer, Christopher; Petrucciani, Giovanni; Pieri, Marco; Ranieri, Riccardo; Sani, Matteo; Sharma, Vivek; Simon, Sean; Sudano, Elizabeth; Tadel, Matevz; Tu, Yanjun; Vartak, Adish; Wasserbaech, Steven; Würthwein, Frank; Yagil, Avraham; Yoo, Jaehyeok; Barge, Derek; Bellan, Riccardo; Campagnari, Claudio; D'Alfonso, Mariarosaria; Danielson, Thomas; Flowers, Kristen; Geffert, Paul; Incandela, Joe; Justus, Christopher; Kalavase, Puneeth; Koay, Sue Ann; Kovalskyi, Dmytro; Krutelyov, Vyacheslav; Lowette, Steven; Mccoll, Nickolas; Pavlunin, Viktor; Rebassoo, Finn; Ribnik, Jacob; Richman, Jeffrey; Rossin, Roberto; Stuart, David; To, Wing; West, Christopher; Apresyan, Artur; Bornheim, Adolf; Chen, Yi; Di Marco, Emanuele; Duarte, Javier; Gataullin, Marat; Ma, Yousi; Mott, Alexander; Newman, Harvey B; Rogan, Christopher; Timciuc, Vladlen; Traczyk, Piotr; Veverka, Jan; Wilkinson, Richard; Yang, Yong; Zhu, Ren-Yuan; Akgun, Bora; Carroll, Ryan; Ferguson, Thomas; Iiyama, Yutaro; Jang, Dong Wook; Liu, Yueh-Feng; Paulini, Manfred; Vogel, Helmut; Vorobiev, Igor; Cumalat, John Perry; Drell, Brian Robert; Edelmaier, Christopher; Ford, William T; Gaz, Alessandro; Heyburn, Bernadette; Luiggi Lopez, Eduardo; Smith, James; Stenson, Kevin; Ulmer, Keith; Wagner, Stephen Robert; Agostino, Lorenzo; Alexander, James; Chatterjee, Avishek; Eggert, Nicholas; Gibbons, Lawrence Kent; Heltsley, Brian; Hopkins, Walter; Khukhunaishvili, Aleko; Kreis, Benjamin; Mirman, Nathan; Nicolas Kaufman, Gala; Patterson, Juliet Ritchie; Ryd, Anders; Salvati, Emmanuele; Sun, Werner; Teo, Wee Don; Thom, Julia; Thompson, Joshua; Vaughan, Jennifer; Weng, Yao; Winstrom, Lucas; Wittich, Peter; Winn, Dave; Abdullin, Salavat; Albrow, Michael; Anderson, Jacob; Bauerdick, Lothar AT; Beretvas, Andrew; Berryhill, Jeffrey; Bhat, Pushpalatha C; Bloch, Ingo; Burkett, Kevin; Butler, Joel Nathan; Chetluru, Vasundhara; Cheung, Harry; Chlebana, Frank; Elvira, Victor Daniel; Fisk, Ian; Freeman, Jim; Gao, Yanyan; Green, Dan; Gutsche, Oliver; Hahn, Alan; Hanlon, Jim; Harris, Robert M; Hirschauer, James; Hooberman, Benjamin; Jindariani, Sergo; Johnson, Marvin; Joshi, Umesh; Kilminster, Benjamin; Klima, Boaz; Kunori, Shuichi; Kwan, Simon; Lincoln, Don; Lipton, Ron; Lueking, Lee; Lykken, Joseph; Maeshima, Kaori; Marraffino, John Michael; Maruyama, Sho; Mason, David; McBride, Patricia; Mishra, Kalanand; Mrenna, Stephen; Musienko, Yuri; Newman-Holmes, Catherine; O'Dell, Vivian; Prokofyev, Oleg; Sexton-Kennedy, Elizabeth; Sharma, Seema; Spalding, William J; Spiegel, Leonard; Tan, Ping; Taylor, Lucas; Tkaczyk, Slawek; Tran, Nhan Viet; Uplegger, Lorenzo; Vaandering, Eric Wayne; Vidal, Richard; Whitmore, Juliana; Wu, Weimin; Yang, Fan; Yumiceva, Francisco; Yun, Jae Chul; Acosta, Darin; Avery, Paul; Bourilkov, Dimitri; Chen, Mingshui; Das, Souvik; De Gruttola, Michele; Di Giovanni, Gian Piero; Dobur, Didar; Drozdetskiy, Alexey; Field, Richard D; Fisher, Matthew; Fu, Yu; Furic, Ivan-Kresimir; Gartner, Joseph; Hugon, Justin; Kim, Bockjoo; Konigsberg, Jacobo; Korytov, Andrey; Kropivnitskaya, Anna; Kypreos, Theodore; Low, Jia Fu; Matchev, Konstantin; Milenovic, Predrag; Mitselmakher, Guenakh; Muniz, Lana; Remington, Ronald; Rinkevicius, Aurelijus; Sellers, Paul; Skhirtladze, Nikoloz; Snowball, Matthew; Yelton, John; Zakaria, Mohammed; Gaultney, Vanessa; Lebolo, Luis Miguel; Linn, Stephan; Markowitz, Pete; Martinez, German; Rodriguez, Jorge Luis; Adams, Todd; Askew, Andrew; Bochenek, Joseph; Chen, Jie; Diamond, Brendan; Gleyzer, Sergei V; Haas, Jeff; Hagopian, Sharon; Hagopian, Vasken; Jenkins, Merrill; Johnson, Kurtis F; Prosper, Harrison; Veeraraghavan, Venkatesh; Weinberg, Marc; Baarmand, Marc M; Dorney, Brian; Hohlmann, Marcus; Kalakhety, Himali; Vodopiyanov, Igor; Adams, Mark Raymond; Anghel, Ioana Maria; Apanasevich, Leonard; Bai, Yuting; Bazterra, Victor Eduardo; Betts, Russell Richard; Callner, Jeremy; Cavanaugh, Richard; Dragoiu, Cosmin; Evdokimov, Olga; Garcia-Solis, Edmundo Javier; Gauthier, Lucie; Gerber, Cecilia Elena; Hofman, David Jonathan; Khalatyan, Samvel; Lacroix, Florent; Malek, Magdalena; O'Brien, Christine; Silkworth, Christopher; Strom, Derek; Varelas, Nikos; Akgun, Ugur; Albayrak, Elif Asli; Bilki, Burak; Chung, Kwangzoo; Clarida, Warren; Duru, Firdevs; Griffiths, Scott; Lae, Chung Khim; Merlo, Jean-Pierre; Mermerkaya, Hamit; Mestvirishvili, Alexi; Moeller, Anthony; Nachtman, Jane; Newsom, Charles Ray; Norbeck, Edwin; Olson, Jonathan; Onel, Yasar; Ozok, Ferhat; Sen, Sercan; Tiras, Emrah; Wetzel, James; Yetkin, Taylan; Yi, Kai; Barnett, Bruce Arnold; Blumenfeld, Barry; Bolognesi, Sara; Fehling, David; Giurgiu, Gavril; Gritsan, Andrei; Guo, Zijin; Hu, Guofan; Maksimovic, Petar; Rappoccio, Salvatore; Swartz, Morris; Whitbeck, Andrew; Baringer, Philip; Bean, Alice; Benelli, Gabriele; Grachov, Oleg; Kenny Iii, Raymond Patrick; Murray, Michael; Noonan, Daniel; Radicci, Valeria; Sanders, Stephen; Stringer, Robert; Tinti, Gemma; Wood, Jeffrey Scott; Zhukova, Victoria; Barfuss, Anne-Fleur; Bolton, Tim; Chakaberia, Irakli; Ivanov, Andrew; Khalil, Sadia; Makouski, Mikhail; Maravin, Yurii; Shrestha, Shruti; Svintradze, Irakli; Gronberg, Jeffrey; Lange, David; Wright, Douglas; Baden, Drew; Boutemeur, Madjid; Calvert, Brian; Eno, Sarah Catherine; Gomez, Jaime; Hadley, Nicholas John; Kellogg, Richard G; Kirn, Malina; Kolberg, Ted; Lu, Ying; Marionneau, Matthieu; Mignerey, Alice; Peterman, Alison; Rossato, Kenneth; Skuja, Andris; Temple, Jeffrey; Tonjes, Marguerite; Tonwar, Suresh C; Twedt, Elizabeth; Bauer, Gerry; Bendavid, Joshua; Busza, Wit; Butz, Erik; Cali, Ivan Amos; Chan, Matthew; Dutta, Valentina; Gomez Ceballos, Guillelmo; Goncharov, Maxim; Hahn, Kristan Allan; Kim, Yongsun; Klute, Markus; Lee, Yen-Jie; Li, Wei; Luckey, Paul David; Ma, Teng; Nahn, Steve; Paus, Christoph; Ralph, Duncan; Roland, Christof; Roland, Gunther; Rudolph, Matthew; Stephans, George; Stöckli, Fabian; Sumorok, Konstanty; Sung, Kevin; Velicanu, Dragos; Wenger, Edward Allen; Wolf, Roger; Wyslouch, Bolek; Xie, Si; Yang, Mingming; Yilmaz, Yetkin; Yoon, Sungho; Zanetti, Marco; Cooper, Seth; Cushman, Priscilla; Dahmes, Bryan; De Benedetti, Abraham; Franzoni, Giovanni; Gude, Alexander; Haupt, Jason; Kao, Shih-Chuan; Klapoetke, Kevin; Kubota, Yuichi; Mans, Jeremy; Pastika, Nathaniel; Rusack, Roger; Sasseville, Michael; Singovsky, Alexander; Tambe, Norbert; Turkewitz, Jared; Cremaldi, Lucien Marcus; Kroeger, Rob; Perera, Lalith; Rahmat, Rahmat; Sanders, David A; Avdeeva, Ekaterina; Bloom, Kenneth; Bose, Suvadeep; Butt, Jamila; Claes, Daniel R; Dominguez, Aaron; Eads, Michael; Jindal, Pratima; Keller, Jason; Kravchenko, Ilya; Lazo-Flores, Jose; Malbouisson, Helena; Malik, Sudhir; Snow, Gregory R; Baur, Ulrich; Godshalk, Andrew; Iashvili, Ia; Jain, Supriya; Kharchilava, Avto; Kumar, Ashish; Shipkowski, Simon Peter; Smith, Kenneth; Alverson, George; Barberis, Emanuela; Baumgartel, Darin; Chasco, Matthew; Haley, Joseph; Trocino, Daniele; Wood, Darien; Zhang, Jinzhong; Anastassov, Anton; Kubik, Andrew; Mucia, Nicholas; Odell, Nathaniel; Ofierzynski, Radoslaw Adrian; Pollack, Brian; Pozdnyakov, Andrey; Schmitt, Michael Henry; Stoynev, Stoyan; Velasco, Mayda; Won, Steven; Antonelli, Louis; Berry, Douglas; Brinkerhoff, Andrew; Hildreth, Michael; Jessop, Colin; Karmgard, Daniel John; Kolb, Jeff; Lannon, Kevin; Luo, Wuming; Lynch, Sean; Marinelli, Nancy; Morse, David Michael; Pearson, Tessa; Ruchti, Randy; Slaunwhite, Jason; Valls, Nil; Warchol, Jadwiga; Wayne, Mitchell; Wolf, Matthias; Ziegler, Jill; Bylsma, Ben; Durkin, Lloyd Stanley; Hill, Christopher; Hughes, Richard; Killewald, Phillip; Kotov, Khristian; Ling, Ta-Yung; Puigh, Darren; Rodenburg, Marissa; Vuosalo, Carl; Williams, Grayson; Winer, Brian L; Adam, Nadia; Berry, Edmund; Elmer, Peter; Gerbaudo, Davide; Halyo, Valerie; Hebda, Philip; Hegeman, Jeroen; Hunt, Adam; Laird, Edward; Lopes Pegna, David; Lujan, Paul; Marlow, Daniel; Medvedeva, Tatiana; Mooney, Michael; Olsen, James; Piroué, Pierre; Quan, Xiaohang; Raval, Amita; Saka, Halil; Stickland, David; Tully, Christopher; Werner, Jeremy Scott; Zuranski, Andrzej; Acosta, Jhon Gabriel; Brownson, Eric; Huang, Xing Tao; Lopez, Angel; Mendez, Hector; Oliveros, Sandra; Ramirez Vargas, Juan Eduardo; Zatserklyaniy, Andriy; Alagoz, Enver; Barnes, Virgil E; Benedetti, Daniele; Bolla, Gino; Bortoletto, Daniela; De Mattia, Marco; Everett, Adam; Hu, Zhen; Jones, Matthew; Koybasi, Ozhan; Kress, Matthew; Laasanen, Alvin T; Leonardo, Nuno; Maroussov, Vassili; Merkel, Petra; Miller, David Harry; Neumeister, Norbert; Shipsey, Ian; Silvers, David; Svyatkovskiy, Alexey; Vidal Marono, Miguel; Yoo, Hwi Dong; Zablocki, Jakub; Zheng, Yu; Guragain, Samir; Parashar, Neeti; Adair, Antony; Boulahouache, Chaouki; Cuplov, Vesna; Ecklund, Karl Matthew; Geurts, Frank JM; Padley, Brian Paul; Redjimi, Radia; Roberts, Jay; Zabel, James; Betchart, Burton; Bodek, Arie; Chung, Yeon Sei; Covarelli, Roberto; de Barbaro, Pawel; Demina, Regina; Eshaq, Yossof; Garcia-Bellido, Aran; Goldenzweig, Pablo; Gotra, Yury; Han, Jiyeon; Harel, Amnon; Korjenevski, Sergey; Miner, Daniel Carl; Vishnevskiy, Dmitry; Zielinski, Marek; Bhatti, Anwar; Ciesielski, Robert; Demortier, Luc; Goulianos, Konstantin; Lungu, Gheorghe; Malik, Sarah; Mesropian, Christina; Arora, Sanjay; Barker, Anthony; Chou, John Paul; Contreras-Campana, Christian; Contreras-Campana, Emmanuel; Duggan, Daniel; Ferencek, Dinko; Gershtein, Yuri; Gray, Richard; Halkiadakis, Eva; Hidas, Dean; Hits, Dmitry; Lath, Amitabh; Panwalkar, Shruti; Park, Michael; Patel, Rishi; Rekovic, Vladimir; Richards, Alan; Robles, Jorge; Rose, Keith; Salur, Sevil; Schnetzer, Steve; Seitz, Claudia; Somalwar, Sunil; Stone, Robert; Thomas, Scott; Cerizza, Giordano; Hollingsworth, Matthew; Spanier, Stefan; Yang, Zong-Chang; York, Andrew; Eusebi, Ricardo; Flanagan, Will; Gilmore, Jason; Kamon, Teruki; Khotilovich, Vadim; Montalvo, Roy; Osipenkov, Ilya; Pakhotin, Yuriy; Perloff, Alexx; Roe, Jeffrey; Safonov, Alexei; Sakuma, Tai; Sengupta, Sinjini; Suarez, Indara; Tatarinov, Aysen; Toback, David; Akchurin, Nural; Damgov, Jordan; Dudero, Phillip Russell; Jeong, Chiyoung; Kovitanggoon, Kittikul; Lee, Sung Won; Libeiro, Terence; Roh, Youn; Volobouev, Igor; Appelt, Eric; Engh, Daniel; Florez, Carlos; Greene, Senta; Gurrola, Alfredo; Johns, Willard; Kurt, Pelin; Maguire, Charles; Melo, Andrew; Sheldon, Paul; Snook, Benjamin; Tuo, Shengquan; Velkovska, Julia; Arenton, Michael Wayne; Balazs, Michael; Boutle, Sarah; Cox, Bradley; Francis, Brian; Goodell, Joseph; Hirosky, Robert; Ledovskoy, Alexander; Lin, Chuanzhe; Neu, Christopher; Wood, John; Yohay, Rachel; Gollapinni, Sowjanya; Harr, Robert; Karchin, Paul Edmund; Kottachchi Kankanamge Don, Chamath; Lamichhane, Pramod; Sakharov, Alexandre; Anderson, Michael; Bachtis, Michail; Belknap, Donald; Borrello, Laura; Carlsmith, Duncan; Cepeda, Maria; Dasu, Sridhara; Gray, Lindsey; Grogg, Kira Suzanne; Grothe, Monika; Hall-Wilton, Richard; Herndon, Matthew; Hervé, Alain; Klabbers, Pamela; Klukas, Jeffrey; Lanaro, Armando; Lazaridis, Christos; Leonard, Jessica; Loveless, Richard; Mohapatra, Ajit; Ojalvo, Isabel; Pierro, Giuseppe Antonio; Ross, Ian; Savin, Alexander; Smith, Wesley H; Swanson, Joshua

    2013-07-16

    The result of a search for heavy long-lived charged particles produced in pp collisions at $\\sqrt{s}$ = 7 TeV at the LHC is described. The data sample has been collected using the CMS detector and corresponds to an integrated luminosity of 5.0 inverse femtobarns. The inner tracking detectors are used to define a sample of events containing tracks with high momentum and high ionization energy loss. A second sample of events with high-momentum and high-ionization tracks satisfying muon identification and long time-of-flight criteria is analyzed independently. In both cases, the results are consistent with the expected background estimated from data. The results are used to establish cross section limits as a function of mass within the context of models with long-lived gluinos, scalar top quarks and scalar taus. Cross section limits on hyper-meson particles, containing new elementary long-lived hyper-quarks predicted by a vector-like confinement model, are also presented. Lower limits at 95% confidence level on...

  9. Visualization of DNA clustered damage induced by heavy ion exposure

    International Nuclear Information System (INIS)

    Tomita, M.; Yatagai, F.

    2003-01-01

    Full text: DNA double-strand breaks (DSBs) are the most lethal damage induced by ionizing radiations. Accelerated heavy-ions have been shown to induce DNA clustered damage, which is two or more DNA lesions induced within a few helical turns. Higher biological effectiveness of heavy-ions could be provided predominantly by induction of complex DNA clustered damage, which leads to non-repairable DSBs. DNA-dependent protein kinase (DNA-PK) is composed of catalytic subunit (DNA-PKcs) and DNA-binding heterodimer (Ku70 and Ku86). DNA-PK acts as a sensor of DSB during non-homologous end-joining (NHEJ), since DNA-PK is activated to bind to the ends of double-stranded DNA. On the other hand, NBS1 and histone H2AX are essential for DSB repair by homologous recombination (HR) in higher vertebrate cells. Here we report that phosphorylated H2AX at Ser139 (named γ-H2AX) and NBS1 form large undissolvable foci after exposure to accelerated Fe ions, while DNA-PKcs does not recognize DNA clustered damage. NBS1 and γ-H2AX colocalized with forming discrete foci after exposure to X-rays. At 0.5 h after Fe ion irradiation, NBS1 and γ-H2AX also formed discrete foci. However, at 3-8 h after Fe ion irradiation, highly localized large foci turned up, while small discrete foci disappeared. Large NBS1 and γ-H2AX foci were remained even 16 h after irradiation. DNA-PKcs recognized Ku-binding DSB and formed foci shortly after exposure to X-rays. DNA-PKcs foci were observed 0.5 h after 5 Gy of Fe ion irradiation and were almost completely disappeared up to 8 h. These results suggest that NBS1 and γ-H2AX can be utilized as molecular marker of DNA clustered damage, while DNA-PK selectively recognizes repairable DSBs by NHEJ

  10. Search for short-lived particles produced on nuclei with a heavy liquid mini bubble chamber

    CERN Multimedia

    2002-01-01

    The aim of this experiment is to search for short-lived particles produced in hadronic interactions on nuclei with our high resolution heavy liquid mini bubble chamber BIBC, aiming to establish the cross-section for associated production in hadron-nucleus collisions, its $A$-dependence and an approximate value of the lifetime. The chamber will be operated at a bubble density of 290 bubbles/cm and with an apparent bubble size of 30 $\\mu$m in real space. In test runs at CERN we measured detection efficiencies which, together with simulations of $D\\bar{D}$ production and decay, lead to a sensitivity of 0.25 events/($\\mu$b/N) per day if the lifetime is of the order of $5\\times10^{-13}$s. A null result after 10 days running time would set an upper limit on the production cross section to $3 \\mu$b. \\\\ \\\\ In order to measure the momenta of charged decay products of short-lived particles, the bubble chamber will be placed 1.80 m upstream of the streamer chamber of the NA5 experiment (MPI). The geometrical acceptance ...

  11. Dynamical decay of nuclei at high temperature: competition between particle emission and fission decay

    International Nuclear Information System (INIS)

    Delagrange, H.; Gregoire, C.; Scheuter, F.; Abe, Y.

    1985-06-01

    A generalized diffusion equation is propounded to follow the time evolution of an excited nucleus towards fission including along the particle decay. This theoretical model is built in order to try to analyse the anomalous behaviour of particle emission observed in many experimental data for heavy-ion induced reactions. Some calculations for the systems 194 Hg, 170 Yb and 248 Cf are presented. A possible extension of this generalized formalism is suggested to deal more consistently with the experimental data. 52 refs. 10 figs.

  12. 7th high energy heavy ion study

    International Nuclear Information System (INIS)

    Bock, R.; Gutbrod, H.H.; Stock, R.

    1985-03-01

    These proceedings contain the articles presented at the named conference. They deal with relativistic heavy ion reactions, the expansion and freeze-out of nuclear matter, anomalon experiments, and multifragmentation and particle correlations in heavy ion reactions. See hints under the relevant topics. (HSI)

  13. Search for heavy long-lived particles that decay to photons at CDF II.

    Science.gov (United States)

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James, E; Jang, D; Jayatilaka, B; Jeans, D; Jeon, E J; Jindariani, S; Johnson, W; Jones, M; Joo, K K; Jun, S Y; Jung, J E; Junk, T R; Kamon, T; Karchin, P E; Kato, Y; Kemp, Y; Kephart, R; Kerzel, U; Khotilovich, V; Kilminster, B; Kim, D H; Kim, H S; Kim, J E; Kim, M J; Kim, S B; Kim, S H; Kim, Y K; Kimura, N; Kirsch, L; Klimenko, S; Klute, M; Knuteson, B; Ko, B R; Kondo, K; Kong, D J; Konigsberg, J; Korytov, A; Kotwal, A V; Kraan, A C; Kraus, J; Kreps, M; Kroll, J; Krumnack, N; Kruse, M; Krutelyov, V; Kubo, T; Kuhlmann, S E; Kuhr, T; Kulkarni, N P; Kusakabe, Y; Kwang, S; Laasanen, A T; Lai, S; Lami, S; Lammel, S; Lancaster, M; Lander, R L; Lannon, K; Lath, A; Latino, G; Lazzizzera, I; LeCompte, T; Lee, E; Lee, J; Lee, J; Lee, Y J; Lee, S W; Lefèvre, R; Leonardo, N; Leone, S; Levy, S; Lewis, J D; Lin, C; Lin, C S; Lindgren, M; Lipeles, E; Lister, A; Litvintsev, D O; Liu, T; Lockyer, N S; Loginov, A; Loreti, M; Lu, R-S; Lucchesi, D; Lujan, P; Lukens, P; Lungu, G; Lyons, L; Lys, J; Lysak, R; Lytken, E; Mack, P; MacQueen, D; Madrak, R; Maeshima, K; Makhoul, K; Maki, T; Maksimovic, P; Malde, S; Malik, S; Manca, G; Margaroli, F; Marginean, R; Marino, C; Marino, C P; Martin, A; Martin, M; Martin, V; Martínez, M; Martínez-Ballarín, R; Maruyama, T; Mastrandrea, P; Masubuchi, T; Matsunaga, H; Mattson, M E; Mazini, R; Mazzanti, P; McFarland, K S; McIntyre, P; McNulty, R; Mehta, A; Mehtala, P; Menzemer, S; Menzione, A; Merkel, P; Mesropian, C; Messina, A; Miao, T; Miladinovic, N; Miles, J; Miller, R; Mills, C; Milnik, M; Mitra, A; Mitselmakher, G; Miyamoto, A; Moed, S; Moggi, N; Mohr, B; Moon, C S; Moore, R; Morello, M; Movilla Fernandez, P; Mülmenstädt, J; Mukherjee, A; Muller, Th; Mumford, R; Murat, P; Mussini, M; Nachtman, J; Nagano, A; Naganoma, J; Nakamura, K; Nakano, I; Napier, A; Necula, V; Neu, C; Neubauer, M S; Nielsen, J; Nodulman, L; Norniella, O; Nurse, E; Oh, S H; Oh, Y D; Oksuzian, I; Okusawa, T; Oldeman, R; Orava, R; Osterberg, K; Pagliarone, C; Palencia, E; Papadimitriou, V; Papaikonomou, A; Paramonov, A A; Parks, B; Pashapour, S; Patrick, J; Pauletta, G; Paulini, M; Paus, C; Pellett, D E; Penzo, A; Phillips, T J; Piacentino, G; Piedra, J; Pinera, L; Pitts, K; Plager, C; Pondrom, L; Portell, X; Poukhov, O; Pounder, N; Prakoshyn, F; Pronko, A; Proudfoot, J; Ptohos, F; Punzi, G; Pursley, J; Rademacker, J; Rahaman, A; Ramakrishnan, V; Ranjan, N; Redondo, I; Reisert, B; Rekovic, V; Renton, P; Rescigno, M; Richter, S; Rimondi, F; Ristori, L; Robson, A; Rodrigo, T; Rogers, E; Rolli, S; Roser, R; Rossi, M; Rossin, R; Roy, P; Ruiz, A; Russ, J; Rusu, V; Saarikko, H; Safonov, A; Sakumoto, W K; Salamanna, G; Saltó, O; Santi, L; Sarkar, S; Sartori, L; Sato, K; Savard, P; Savoy-Navarro, A; Scheidle, T; Schlabach, P; Schmidt, E E; Schmidt, M P; Schmitt, M; Schwarz, T; Scodellaro, L; Scott, A L; Scribano, A; Scuri, F; Sedov, A; Seidel, S; Seiya, Y; Semenov, A; Sexton-Kennedy, L; Sfyrla, A; Shalhout, S Z; Shapiro, M D; Shears, T; Shepard, P F; Sherman, D; Shimojima, M; Shochet, M; Shon, Y; Shreyber, I; Sidoti, A; Sinervo, P; Sisakyan, A; Slaughter, A J; Slaunwhite, J; Sliwa, K; Smith, J R; Snider, F D; Snihur, R; Soderberg, M; Soha, A; Somalwar, S; Sorin, V; Spalding, J; Spinella, F; Spreitzer, T; Squillacioti, P; Stanitzki, M; Staveris-Polykalas, A; St Denis, R; Stelzer, B; Stelzer-Chilton, O; Stentz, D; Strologas, J; Stuart, D; Suh, J S; Sukhanov, A; Sun, H; Suslov, I; Suzuki, T; Taffard, A; Takashima, R; Takeuchi, Y; Tanaka, R; Tecchio, M; Teng, P K; Terashi, K; Thom, J; Thompson, A S; Thomson, E; Tipton, P; Tiwari, V; Tkaczyk, S; Toback, D; Tokar, S; Tollefson, K; Tomura, T; Tonelli, D; Torre, S; Torretta, D; Tourneur, S; Trischuk, W; Tsuno, S; Tu, Y; Turini, N; Ukegawa, F; Uozumi, S; Vallecorsa, S; van Remortel, N; Varganov, A; Vataga, E; Vazquez, F; Velev, G; Veramendi, G; Veszpremi, V; Vidal, M; Vidal, R; Vila, I; Vilar, R; Vine, T; Vollrath, I; Volobouev, I; Volpi, G; Würthwein, F; Wagner, P; Wagner, R G; Wagner, R L; Wagner, J; Wagner, W; Wallny, R; Wang, S M; Warburton, A; Waters, D; Weinberger, M; Wester, W C; Whitehouse, B; Whiteson, D; Wicklund, A B; Wicklund, E; Williams, G; Williams, H H; Wilson, P; Winer, B L; Wittich, P; Wolbers, S; Wolfe, C; Wright, T; Wu, X; Wynne, S M; Yagil, A; Yamamoto, K; Yamaoka, J; Yamashita, T; Yang, C; Yang, U K; Yang, Y C; Yao, W M; Yeh, G P; Yoh, J; Yorita, K; Yoshida, T; Yu, G B; Yu, I; Yu, S S; Yun, J C; Zanello, L; Zanetti, A; Zaw, I; Zhang, X; Zhou, J; Zucchelli, S

    2007-09-21

    We present the first search for heavy, long-lived particles that decay to photons at a hadron collider. We use a sample of gamma + jet + missing transverse energy events in pp[over] collisions at square root[s] = 1.96 TeV taken with the CDF II detector. Candidate events are selected based on the arrival time of the photon at the detector. Using an integrated luminosity of 570 pb(-1) of collision data, we observe 2 events, consistent with the background estimate of 1.3+/-0.7 events. While our search strategy does not rely on model-specific dynamics, we set cross section limits in a supersymmetric model with [Formula: see text] and place the world-best 95% C.L. lower limit on the [Formula: see text] mass of 101 GeV/c(2) at [Formula: see text].

  14. Carbon Heavy-ion Radiation Induced Biological effects on Oryza sativa L.

    Science.gov (United States)

    Zhang, Meng; Sun, Yeqing; Li, Xishan; Gong, Ning; Meng, Qingmei; Liu, Jiawei; Wang, Ting

    2016-07-01

    Large number of researches on rice after spaceflights indicated that rice was a favorable model organism to study biological effects induced by space radiation. The stimulative effect could often be found on rice seedlings after irradiation by low-dose energetic heavy-ion radiation. Spaceflight also could induce stimulative effect on kinds of seeds. To further understand the mechanism of low-dose radiation biological effects and the dose range, the germinated rice seeds which were irradiated by different doses of carbon heavy-ion (0, 0.02, 0.1, 0.2, 1, 2, 5, 10, 15 and 20Gy, LET=27.3keV/µm) were used as materials to study. By investigating the variation of rice phenotype under different doses, we found that 2Gy radiation dose was a dividing point of the phenotypic variation. Transmission electron microscopy was used to observe the variation of mitochondria, chloroplast, endoplasmic reticulum, ribosome and nucleus in mesophyll cell of rice apical meristem at 24 hours after radiation with different doses. The cells were not apparently physiologically damaged when the dose of radiation was less than 2Gy. The number of chloroplast did not change significantly, but the number of mitochondria was significantly increased, and gathered around in the chloroplast and endoplasmic reticulum; the obvious lesion of chloroplast and mitochondria were found at the mesophyll cells when radiation dose was higher than 2Gy. The mitochondria were swelling and appearing blurred crest. The chloroplast and mitochondrial mutation rate increased significantly (pmitochondrial was an important organelle involved in the antioxidative systems, its dysfunction could result in the increase of reactive oxygen species and lipid peroxidation. We found that the growth stimulation induced by low-dose radiation mainly occurred at three-leaf stage along with the increasing activity of antioxidase system and damages of lipid peroxidation. We also found that the relative expression of genes sdhb and aox1a

  15. Alpha-particles induce autophagy in multiple myeloma cells

    Directory of Open Access Journals (Sweden)

    Joelle Marcelle Gaschet

    2015-10-01

    Full Text Available Objectives: Radiations emitted by the radionuclides in radioimmunotherapy (RIT approaches induce direct killing of the targeted cells as well as indirect killing through bystander effect. Our research group is dedicated to the development of α-RIT, i.e RIT using α-particles especially for the treatment of multiple myeloma (MM. γ-irradiation and β-irradiation have been shown to trigger apoptosis in tumor cells. Cell death mode induced by 213Bi α-irradiation appears more controversial. We therefore decided to investigate the effects of 213Bi on MM cell radiobiology, notably cell death mechanisms as well as tumor cell immunogenicity after irradiation.Methods: Murine 5T33 and human LP-1 multiple myeloma (MM cell lines were used to study the effects of such α-particles. We first examined the effects of 213Bi on proliferation rate, double strand DNA breaks, cell cycle and cell death. Then, we investigated autophagy after 213Bi irradiation. Finally, a co-culture of dendritic cells (DC with irradiated tumour cells or their culture media was performed to test whether it would induce DC activation.Results: We showed that 213Bi induces DNA double strand breaks, cell cycle arrest and autophagy in both cell lines but we detected only slight levels of early apoptosis within the 120 hours following irradiation in 5T33 and LP-1. Inhibition of autophagy prevented 213Bi induced inhibition of proliferation in LP-1 suggesting that this mechanism is involved in cell death after irradiation. We then assessed the immunogenicity of irradiated cells and found that irradiated LP-1 can activate DC through the secretion of soluble factor(s, however no increase in membrane or extracellular expression of danger associated molecular patterns (DAMPs was observed after irradiation.Conclusion: This study demonstrates that 213Bi induces mainly necrosis in MM cells, low levels of apoptosis and also autophagy that might be involved in tumor cell death.

  16. Laser-induced breakdown spectroscopy for detection of heavy metals in environmental samples

    Science.gov (United States)

    Wisbrun, Richard W.; Schechter, Israel; Niessner, Reinhard; Schroeder, Hartmut

    1993-03-01

    The application of LIBS technology as a sensor for heavy metals in solid environmental samples has been studied. This specific application introduces some new problems in the LIBS analysis. Some of them are related to the particular distribution of contaminants in the grained samples. Other problems are related to mechanical properties of the samples and to general matrix effects, like the water and organic fibers content of the sample. An attempt has been made to optimize the experimental set-up for the various involved parameters. The understanding of these factors has enabled the adjustment of the technique to the substrates of interest. The special importance of the grain size and of the laser-induced aerosol production is pointed out. Calibration plots for the analysis of heavy metals in diverse sand and soil samples have been carried out. The detection limits are shown to be usually below the recent regulation restricted concentrations.

  17. Optimization of laser-induced breakdown spectroscopy for coal powder analysis with different particle flow diameters

    Energy Technology Data Exchange (ETDEWEB)

    Yao, Shunchun, E-mail: epscyao@scut.edu.cn [School of Electric Power, South China University of Technology, Guangzhou, Guangdong 510640 (China); State Key Laboratory of Pulsed Power Laser Technology, Electronic Engineering Institute, Hefei 230037 (China); Xu, Jialong; Dong, Xuan; Zhang, Bo; Zheng, Jianping [School of Electric Power, South China University of Technology, Guangzhou, Guangdong 510640 (China); Lu, Jidong, E-mail: jdlu@scut.edu.cn [School of Electric Power, South China University of Technology, Guangzhou, Guangdong 510640 (China)

    2015-08-01

    The on-line measurement of coal is extremely useful for emission control and combustion process optimization in coal-fired plant. Laser-induced breakdown spectroscopy was employed to directly analyze coal particle flow. A set of tapered tubes were proposed for beam-focusing the coal particle flow to different diameters. For optimizing the measurement of coal particle flow, the characteristics of laser-induced plasma, including optical breakdown, the relative standard deviation of repeated measurement, partial breakdown spectra ratio and line intensity, were carefully analyzed. The comparison of the plasma characteristics among coal particle flow with different diameters showed that air breakdown and the random change in plasma position relative to the collection optics could significantly influence on the line intensity and the reproducibility of measurement. It is demonstrated that the tapered tube with a diameter of 5.5 mm was particularly useful to enrich the coal particles in laser focus spot as well as to reduce the influence of air breakdown and random changes of plasma in the experiment. - Highlights: • Tapered tube was designed for beam-focusing the coal particle flow as well as enriching the particles in laser focus spot. • The characteristics of laser-induced plasma of coal particle flow were investigated carefully. • An appropriate diameter of coal particle flow was proven to benefit for improving the performance of LIBS measurement.

  18. Resonant pickups for non-destructive single-particle detection in heavy-ion storage rings and first experimental results

    Energy Technology Data Exchange (ETDEWEB)

    Sanjari, Mohammad Shahab

    2013-04-26

    Nuclear astrophysics studies on highly charged radionuclides benefit from accelerator facilities with storage rings, where exotic nuclides produced with small yields can be efficiently investigated. Currently there are two accelerator facilities capable of storing highly charged heavy ions, GSI in Darmstadt and IMP in Lanzhou. Non-destructive detection methods are often used for in-flight measurements based on frequency analysis. The sensitivity of such detection systems are of primary importance specially when number of stored ions is small. Furthermore, since the exotic nuclides of interest are as a rule short-lived, the detectors must be fast. One common form of such detectors are parallel plate SCHOTTKY monitors, on which particles induce a mirror charge at each passage. This method has been successfully used at ESR experimental storage ring of GSI since 1991. In this work we describe a new resonant SCHOTTKY pickup operating as a high sensitive cavity current monitor which was mounted and commissioned in the ESR early 2010. It was successfully used in several storage ring experiments. A very similar pickup was mounted in CSRe at IMP Lanzhou in 2011. First in-ring tests have been performed and new experimental results are pending. The spectral analysis of acquired signals by the new detector has enabled a broad range of new physics experiments. The theory of operation and first experimental results and future perspectives are presented in this thesis.

  19. Resonant pickups for non-destructive single-particle detection in heavy-ion storage rings and first experimental results

    International Nuclear Information System (INIS)

    Sanjari, Mohammad Shahab

    2013-01-01

    Nuclear astrophysics studies on highly charged radionuclides benefit from accelerator facilities with storage rings, where exotic nuclides produced with small yields can be efficiently investigated. Currently there are two accelerator facilities capable of storing highly charged heavy ions, GSI in Darmstadt and IMP in Lanzhou. Non-destructive detection methods are often used for in-flight measurements based on frequency analysis. The sensitivity of such detection systems are of primary importance specially when number of stored ions is small. Furthermore, since the exotic nuclides of interest are as a rule short-lived, the detectors must be fast. One common form of such detectors are parallel plate SCHOTTKY monitors, on which particles induce a mirror charge at each passage. This method has been successfully used at ESR experimental storage ring of GSI since 1991. In this work we describe a new resonant SCHOTTKY pickup operating as a high sensitive cavity current monitor which was mounted and commissioned in the ESR early 2010. It was successfully used in several storage ring experiments. A very similar pickup was mounted in CSRe at IMP Lanzhou in 2011. First in-ring tests have been performed and new experimental results are pending. The spectral analysis of acquired signals by the new detector has enabled a broad range of new physics experiments. The theory of operation and first experimental results and future perspectives are presented in this thesis.

  20. The role of soil's particle-size fractions in the adsorption of heavy metals

    Directory of Open Access Journals (Sweden)

    Saglara Mandzhieva

    2014-08-01

    Full Text Available The parameters of adsorption of Cu2+, Pb2+, and Zn2+ cations by southern chernozem and their particle-size fractions were studied. The adsorption of metals by soils and the strength of their fixation on the surface of soil particles under both mono- and poly-element contamination decreased with the decreasing proportion of fine fractions in the soil. The aim of this work was to study the effect of the particle-size distribution and the silt and physical clay fractions on the adsorption of copper, lead, and zinc by chernozems. The objects of study included the upper humus horizons of different southern chernozems of the Rostov oblast. To study the ion-exchange adsorption of the Cu2+, Pb2+, and Zn2+ cations, the soil in the natural ionic form was disaggregated using a pestle with a rubber head and sieved through a 1mm sieve. The soil samples were treated with solutions of Cu2+, Pb2+, and Zn2+ nitrates and acetates at the separate and simultaneous presence of heavy metals (HMs. In the solutions with the simultaneous presence of HMs, their molar concentrations were similar. The concentrations of the initial solutions varied in the range from 0.05 to 1 mM/l. The soil: solution ratio was 1:10. The contents of HMs in the filtrates were determined by atomic absorption spectrophotometry. The contents of adsorbed HM cations were calculated from the difference between the metal concentrations in the initial and equilibrium solutions. The increase in the degree of dispersion of the particle-size fractions in similar soils resulted not only in an increase in the content of adsorbed HMs but also in an enhancement of their fixation on the surface of the fine particles. Therefore, the adsorption capacity of the Lower Don soils for Cu2+, Pb2+, and Zn2+ decreased in the following sequence: clay loamy southern chernozem > loamy southern chernozem > loamy sandy southern chernozem. This was related to the qualitative differences in the mineralogy and chemistry of

  1. Spatiotemporal kinetics of γ-H2AX protein on charged particles induced DNA damage

    Energy Technology Data Exchange (ETDEWEB)

    Niu, H., E-mail: hniu@mx.nthu.edu.tw [Nuclear Science and Technology Development Center, National Tsing Hua University, Hsinchu, Taiwan (China); Chang, H.C. [Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan (China); Cho, I.C. [Institute for Radiological Research, Chang Gung University and Chang Gung Memorial Hospital, Taoyuan, Taiwan (China); Chen, C.H. [Nuclear Science and Technology Development Center, National Tsing Hua University, Hsinchu, Taiwan (China); Liu, C.S. [Cancer Center of Taipei Veterans General Hospital, Taipei, Taiwan (China); Chou, W.T. [Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan (China)

    2014-08-15

    Highlights: • Charged particles can induce more complex DNA damages, and these complex damages have higher ability to cause the cell death or cell carcinogenesis. • In this study, we used γ-H2AX protein to investigate the spatiotemporal kinetics of DNA double strand breaks in particle irradiated HeLa cells. • The HeLa cells were irradiated by 400 keV alpha-particles in four different dosages. • The result shows that a good linear relationship can be observed between foci number and radiation dose. • The data shows that the dissolution rate of γ-H2AX foci agree with the two components DNA repairing model, and it was decreasing as the radiation dose increased. • These results suggest that charged particles can induce more complex DNA damages and causing the retardation of DNA repair. - Abstract: In several researches, it has been demonstrated that charged particles can induce more complex DNA damages. These complex damages have higher ability to cause the cell death or cell carcinogenesis. For this reason, clarifying the DNA repair mechanism after charged particle irradiation plays an important role in the development of charged particle therapy and space exploration. Unfortunately, the detail spatiotemporal kinetic of DNA damage repair is still unclear. In this study, we used γ-H2AX protein to investigate the spatiotemporal kinetics of DNA double strand breaks in alpha-particle irradiated HeLa cells. The result shows that the intensity of γ-H2AX foci increased gradually, and reached to its maximum at 30 min after irradiation. A good linear relationship can be observed between foci intensity and radiation dose. After 30 min, the γ-H2AX foci intensity was decreased with time passed, but remained a large portion (∼50%) at 48 h passed. The data show that the dissolution rate of γ-H2AX foci agreed with two components DNA repairing model. These results suggest that charged particles can induce more complex DNA damages and causing the retardation of DNA

  2. Energy dependence and temporal evolution of the 3He/4He ratios in heavy-ion-rich energetic particle events

    International Nuclear Information System (INIS)

    Moebius, E.; Hovestadt, D.; Klecker, B.; Gloeckler, G.

    1980-01-01

    The energy dependence of the 3 He/ 4 He ratio between 0.44 and 4.1 MeV per nucleon has been studied for six heavy-ion--rich events observed in 1974 and 1976 using the low-energy dE/dx versus E Ultralow-Energy Particle telescope (ULET) on IMP 8. We find that all selected heavy-ion--rich events are also enriched in 3 He, that the 3 He/ 4 He He ratio decreases with decreasing energies, and that a rapid temporal evolution of the 3 He/ 4 He and the Fe/(H+He) ratios is strongly correlated during one event with the maximum value at the onset. These results are discussed in terms of a model which is based on preferential injection of 3 He and Fe resulting from turbulent ion heating and subsequent Fermi acceleration

  3. Suppressing Heavy Metal Leaching through Ball Milling of Fly Ash

    Directory of Open Access Journals (Sweden)

    Zhiliang Chen

    2016-07-01

    Full Text Available Ball milling is investigated as a method of reducing the leaching concentration (often termed stablilization of heavy metals in municipal solid waste incineration (MSWI fly ash. Three heavy metals (Cu, Cr, Pb loose much of their solubility in leachate by treating fly ash in a planetary ball mill, in which collisions between balls and fly ash drive various physical processes, as well as chemical reactions. The efficiency of stabilization is evaluated by analysing heavy metals in the leachable fraction from treated fly ash. Ball milling reduces the leaching concentration of Cu, Cr, and Pb, and water washing effectively promotes stabilization efficiency by removing soluble salts. Size distribution and morphology of particles were analysed by laser particle diameter analysis and scanning electron microscopy. X-ray diffraction analysis reveals significant reduction of the crystallinity of fly ash by milling. Fly ash particles can be activated through this ball milling, leading to a significant decrease in particle size, a rise in its BET-surface, and turning basic crystals therein into amorphous structures. The dissolution rate of acid buffering materials present in activated particles is enhanced, resulting in a rising pH value of the leachate, reducing the leaching out of some heavy metals.

  4. Heavy ion induced fission between 10 and 100 MeV/u

    International Nuclear Information System (INIS)

    Steckmeyer, J.C.; Tamain, B.

    1986-05-01

    Heavy ion induced fission between 10 and 100 MeV/u is discussed. It is shown that one can obtain information on fusion limits and on typical times characterizing nuclear matter. Intermediate energy heavy ions can be used to build very excited fusion nuclei. Section I shows that fission can then be used as a tool to test the fusion mechanism and to discover what are the extreme limits concerning fusion and hot nuclei formation. In section II, it is shown that when very hot nuclei are built, fission evaporation competition cannot any longer be fully described in the usual way by the statistical model. New features as dynamical aspects or cluster evaporation modify dramatically the landscape. Concerning the detailed fission properties of very hot nuclei (for instance fragments properties), no strong deviations from the already know systematics has been obtained. However, very few detailed studies are yet available and a clear experimental program has to be developed in order to progress. From a theoretical point of view, it is rather necessary to described fission and evaporation is an unified way

  5. Monitoring of heavy metal particle emission in the exhaust duct of a foundry using LIBS.

    Science.gov (United States)

    Dutouquet, C; Gallou, G; Le Bihan, O; Sirven, J B; Dermigny, A; Torralba, B; Frejafon, E

    2014-09-01

    Heavy metals have long been known to be detrimental to human health and the environment. Their emission is mainly considered to occur via the atmospheric route. Most of airborne heavy metals are of anthropogenic origin and produced through combustion processes at industrial sites such as incinerators and foundries. Current regulations impose threshold limits on heavy metal emissions. The reference method currently implemented for quantitative measurements at exhaust stacks consists of on-site sampling of heavy metals on filters for the particulate phase (the most prominent and only fraction considered in this study) prior to subsequent laboratory analysis. Results are therefore known only a few days after sampling. Stiffer regulations require the development of adapted tools allowing automatic, on-site or even in-situ measurements with temporal resolutions. The Laser-Induced Breakdown Spectroscopy (LIBS) technique was deemed as a potential candidate to meet these requirements. On site experiments were run by melting copper bars and monitoring emission of this element in an exhaust duct at a pilot-scale furnace in a French research center dedicated to metal casting. Two approaches designated as indirect and direct analysis were broached in these experiments. The former corresponds to filter enrichment prior to subsequent LIBS interrogation whereas the latter entails laser focusing right through the aerosol for detection. On-site calibration curves were built and compared with those obtained at laboratory scale in order to investigate possible matrix and analyte effects. Eventually, the obtained results in terms of detection limits and quantitative temporal monitoring of copper emission clearly emphasize the potentialities of the direct LIBS measurements. Copyright © 2014 Elsevier B.V. All rights reserved.

  6. Total Particle Number Emissions from Modern Diesel, Natural Gas, and Hybrid Heavy-Duty Vehicles During On-Road Operation.

    Science.gov (United States)

    Wang, Tianyang; Quiros, David C; Thiruvengadam, Arvind; Pradhan, Saroj; Hu, Shaohua; Huai, Tao; Lee, Eon S; Zhu, Yifang

    2017-06-20

    Particle emissions from heavy-duty vehicles (HDVs) have significant environmental and public health impacts. This study measured total particle number emission factors (PNEFs) from six newly certified HDVs powered by diesel and compressed natural gas totaling over 6800 miles of on-road operation in California. Distance-, fuel- and work-based PNEFs were calculated for each vehicle. Distance-based PNEFs of vehicles equipped with original equipment manufacturer (OEM) diesel particulate filters (DPFs) in this study have decreased by 355-3200 times compared to a previous retrofit DPF dynamometer study. Fuel-based PNEFs were consistent with previous studies measuring plume exhaust in the ambient air. Meanwhile, on-road PNEF shows route and technology dependence. For vehicles with OEM DPFs and Selective Catalytic Reduction Systems, PNEFs under highway driving (i.e., 3.34 × 10 12 to 2.29 × 10 13 particles/mile) were larger than those measured on urban and drayage routes (i.e., 5.06 × 10 11 to 1.31 × 10 13 particles/mile). This is likely because a significant amount of nucleation mode volatile particles were formed when the DPF outlet temperature reached a critical value, usually over 310 °C, which was commonly achieved when vehicle speed sustained over 45 mph. A model year 2013 diesel HDV produced approximately 10 times higher PNEFs during DPF active regeneration events than nonactive regeneration.

  7. Characterization of Inherent Particles and Mechanism of Thermal Stress Induced Particle Formation in HSV-2 Viral Vaccine Candidate.

    Science.gov (United States)

    Li, Lillian; Kirkitadze, Marina; Bhandal, Kamaljit; Roque, Cristopher; Yang, Eric; Carpick, Bruce; Rahman, Nausheen

    2017-11-10

    Vaccine formulations may contain visible and/or subvisible particles, which can vary in both size and morphology. Extrinsic particles, which are particles not part of the product such as foreign contaminants, are generally considered undesirable and should be eliminated or controlled in injectable products. However, biological products, in particular vaccines, may also contain particles that are inherent to the product. Here we focus on the characterization of visible and subvisible particles in a live, replication-deficient viral vaccine candidate against HSV genital herpes in an early developmental stage. HSV-2 viral vaccine was characterized using a panel of analytical methods, including Fourier transform infrared spectroscopy (FTIR), sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), Western blot, liquid chromatography-mass spectrometry (LC-MS), light microscopy, transmission electron microscopy (TEM), micro-flow imaging (MFI), dynamic light scattering (DLS), right angle light scattering (RALS), and intrinsic fluorescence. Particles in HSV-2 vaccine typically ranged from hundreds of nanometers to hundreds of micrometers in size and were determined to be inherent to the product. The infectious titer did not correlate with any trend in subvisible particle concentration and size distribution as shown by DLS, MFI, and TEM under stressed conditions. This suggested that particle changes in the submicron range were related to HSV-2 virion structure and had direct impact on biological activity. It was also observed that subvisible and visible particles could induce aggregation in the viral product. The temperature induced aggregation was observed by RALS, intrinsic fluorescence, and DLS. The increase of subvisible particle size with temperature could be fitted to a two-step thermokinetic model. Visible and subvisible particles were found to be inherent to the HSV-2 viral vaccine product. The mechanism of protein aggregation was discussed and a two

  8. Toxicogenomic analysis of the particle dose- and size-response relationship of silica particles-induced toxicity in mice

    International Nuclear Information System (INIS)

    Lu Xiaoyan; Jin Tingting; Jin Yachao; Wu Leihong; Hu Bin; Tian Yu; Fan Xiaohui

    2013-01-01

    This study investigated the relationship between particle size and toxicity of silica particles (SP) with diameters of 30, 70, and 300 nm, which is essential to the safe design and application of SP. Data obtained from histopathological examinations suggested that SP of these sizes can all induce acute inflammation in the liver. In vivo imaging showed that intravenously administrated SP are mainly present in the liver, spleen and intestinal tract. Interestingly, in gene expression analysis, the cellular response pathways activated in the liver are predominantly conserved independently of particle dose when the same size SP are administered or are conserved independently of particle size, surface area and particle number when nano- or submicro-sized SP are administered at their toxic doses. Meanwhile, integrated analysis of transcriptomics, previous metabonomics and conventional toxicological results support the view that SP can result in inflammatory and oxidative stress, generate mitochondrial dysfunction, and eventually cause hepatocyte necrosis by neutrophil-mediated liver injury. (paper)

  9. 4. Workshop on heavy charged particles in biology and medicine in connection with the XV PTCOG meeting. Book of abstracts

    International Nuclear Information System (INIS)

    Kraft, G.

    1991-09-01

    The fourth workshop on heavy charged particles in biology and medicine is held after a long break of 4 years. For the biological response of cells or subcellar objects, the experiment is still the only source of safe information. A large and still growing community performs these experiments as it is demonstrated by the numerous presentations of this workshop. This research has been extended to a more molecular level like DNA as well as to completly different systems like the cellular membran. There again, new and surprising results have been found. Finally, the problems of radiobiological research has stimulated atomic physicists to reconsider and to measure the emission of electrons in heavy ion-atom collisions. These experiments indicate that the conventional understanding of track formation has to be revised too. (orig./VHE)

  10. Detection of heavy metals in soils by laser-induced breakdown spectroscopy (LIBS)

    International Nuclear Information System (INIS)

    Sirven, Jean-Baptiste

    2006-01-01

    In the fields of analysis, control and physical measurement, the laser constitutes a particularly powerful and multi-purpose metrological tool, capable to bring concrete solutions to various matters, including of a societal nature. Among the latter, contamination of sites and soils by heavy metals is an important issue of public health which requires to have measurement means adapted to existing regulations and whose use be sufficiently flexible. As a fast technique which does not need any sample preparation, laser-induced breakdown spectroscopy (LIBS) offers very interesting advantages for making on-site measurements of heavy metals content at the 10-ppm level; the design of a portable system is conceivable in the medium term. In this work we first show that the femtosecond regime presents no advantages with respect to the standard nanosecond regime for our issue. Then we implement an advanced treatment of LIBS spectra by chemometric techniques whose performances significantly improve the results of qualitative and quantitative analyses of soils samples. (author)

  11. Searching for Jets in Heavy Ion Collisions

    International Nuclear Information System (INIS)

    Salur, Sevil

    2008-01-01

    Jet quenching measurements using leading particles and their correlations suffer from known biases, which can be removed via direct reconstruction of jets in central heavy ion collisions. In this talk, we discuss several modern jet reconstruction algorithms and background subtraction techniques that are appropriate to heavy ion collisions

  12. Erratum: Erratum to: Thermodynamic implications of the gravitationally induced particle creation scenario

    Science.gov (United States)

    Saha, Subhajit; Mondal, Anindita

    2018-04-01

    We would like to rectify an error regarding the validity of the first law of thermodynamics (FLT) on the apparent horizon of a spatially flat Friedmann-Lemaitre-Robertson-Walker (FLRW) universe for the gravitationally induced particle creation scenario with constant specific entropy and an arbitrary particle creation rate (see Sect. 3.1 of original article)

  13. Theory and phenomenology of the MSSM with heavy scalars

    International Nuclear Information System (INIS)

    Bernal Hernandez, N.

    2008-09-01

    This work is dedicated to the study of different phenomenological aspects of supersymmetry with on one hand the physics of the Minimal Supersymmetric Standard Model (MSSM) in the case of heavy scalar superparticles and its implications at the LHC and on the other hand the characteristics of black matter particles and their detection in colliders and in astro-particle experiments. The first chapter presents the Standard Model, the supersymmetry theory and how the supersymmetric extension of the Standard Model can solve some concerns of the Standard Model. In the second chapter we present the MSSM with heavy scalars. In this model all the scalar particles have masses beyond the TeV and consequently even next generations of colliders will not be able to detect them. We recall why heavy scalars are necessary. In the third chapter we present the construction of MSSM parameters with heavy scalars and we show that the future ILC (International Linear Collider) will be able to set the value of these parameters with a satisfactory accuracy. The last chapter deals with dark matter particles like WIMPS, their detection sensitivity in the XENON experiment and the reconstruction of their masses will be analyzed. We have also studied the direct detection of WIMPS via the observation of some products of their annihilation

  14. Quantitative nitric oxide measurements by means of laser-induced fluorescence in a heavy-duty Diesel engine

    NARCIS (Netherlands)

    Verbiezen, K.; Vliet, van A.P.; Klein-Douwel, R.J.H.; Ganippa, L.C.; Bougie, H.J.T.; Meerts, W.L.; Dam, N.J.; Meulen, ter J.J.

    2005-01-01

    Quantitative in-cylinder laser-induced fluorescence measurements ofnitric oxide in a heavy-duty Diesel engine are presented. Special attention is paid to experimental techniques to assess the attenuation of the laser beam and the fluorescence signal by the cylinder contents.This attenuation can be

  15. Simulation study of radial dose due to the irradiation of a swift heavy ion aiming to advance the treatment planning system for heavy particle cancer therapy: The effect of emission angles of secondary electrons

    Energy Technology Data Exchange (ETDEWEB)

    Moribayashi, Kengo, E-mail: moribayashi.kengo@jaea.go.jp

    2015-12-15

    A radial dose simulation model has been proposed in order to advance the treatment planning system for heavy particle cancer therapy. Here, the radial dose is the dose due to the irradiation of a heavy ion as a function of distances from this ion path. The model proposed here may overcome weak points of paradigms that are employed to produce the conventional radial dose distributions. To provide the radial dose with higher accuracy, this paper has discussed the relationship between the emission angles of secondary electrons and the radial dose. It is found that the effect of emission angles becomes stronger on the radial dose with increasing energies of the secondary electrons.

  16. New particle searches and discoveries

    International Nuclear Information System (INIS)

    Trippe, T.G.; Barbaro-Galtieri, A.; Horne, C.P.; Kelly, R.L.; Rittenberg, A.; Rosenfeld, A.H.; Yost, G.P.; Armstrong, B.; Bricman, C.; Hemingway, R.J.; Losty, M.J.; Roos, M.

    1977-01-01

    This supplement to the 1976 edition of 'Review of particle properties', Particle Data Group [Rev. Mod. Phys. 48, No. 2, Part II (1976)], contains tabulations of experimental data bearing on the 'new particles' and related topics; categories covered include charmed particles, psi's and their decay products, and heavy leptons. Errata to the previous edition are also given. (Auth.)

  17. Radial diffusion of toroidally trapped particles induced by lower hybrid and fast waves

    International Nuclear Information System (INIS)

    Krlin, L.

    1992-10-01

    The interaction of RF field with toroidally trapped particles (bananas) can cause their intrinsic stochastically diffusion both in the configuration and velocity space. In RF heating and/or current drive regimes, RF field can interact with plasma particles and with thermonuclear alpha particles. The aim of this contribution is to give some analytical estimates of induced radial diffusion of alphas and of ions. (author)

  18. Mesh refinement for particle-in-cell plasma simulations: Applications to - and benefits for HIF (heavy ion fusion)

    International Nuclear Information System (INIS)

    Vay, J.L.; Colella, P.; McCorquodale, P.; Van Straalen, B.; Friedman, A.; Grote, D.P.

    2002-01-01

    The numerical simulation of the driving beams in a heavy ion fusion power plant is a challenging task, and simulation of the power plant as a whole, or even of the drive,r is not yet possible. Despite the rapid progress in computer power, past and anticipated, one must consider the use of the most advanced numerical techniques, if they are to reach the goal expeditiously. One of the difficulties of these simulations resides in the disparity of scales, in time and in space, which must be resolved. When these disparities are in distinctive zones of the simulation region, a method which has proven to be effective in other areas (e.g., fluid dynamics simulations) is the mesh refinement technique. They discuss the challenges posed by the implementation of this technique into plasma simulations (due to the presence of particles and electromagnetic waves). They will present the prospects for and projected benefits of its application to heavy ion fusion, in particular to the simulation of the ion source and the final beam propagation in the chamber

  19. Monitoring transport and equilibrium of heavy metals in soil using induced polarization

    Science.gov (United States)

    Shalem, T.; Huisman, J. A.; Zimmermann, E.; Furman, A.

    2017-12-01

    Soil and groundwater pollution in general, and by heavy metals in particular, is a major threat to human health, and especially in rapidly developing regions, such as China. Fast, accurate and low-cost measurement of heavy metal contamination is of high desire. Spectral induced polarization (SIP) may be an alternative to the tedious sampling techniques typically used. In the SIP method, an alternating current at a range of low frequencies is injected into the soil and the resultant potential is measured along the current's path. SIP is a promising method for monitoring heavy metals, because it is sensitive to the chemical composition of both the absorbed ions on the soil minerals and the pore fluid and to the interface between the two. The high sorption affinity of heavy metals suggests that their electrical signature may be significant, even at relatively low concentrations. The goal of this research is to examine the electrical signature of soil contaminated by heavy metals and of the pollution transport and remediation processes, in a non-tomographic fashion. Specifically, we are looking at the SIP response of various heavy metals in several settings: 1) at equilibrium state in batch experiments; 2) following the progress of a pollution front along a soil column through flow experiments and 3) monitoring the extraction of the contaminant by a chelating agent. Using the results, we develop and calibrate a multi-Cole-Cole model to separate the electrochemical and the interfacial components of the polarization. Last, we compare our results to the electrical signature of contaminated soil from southern China. Results of single metals from both batch and flow experiments display a shift of the relaxation time and a decrease in the phase response of the soil with increase of the metal concentration, suggesting strong sorption of the metals on the stern layer. Preliminary results also show evidence of electrodic polarization, assuming to be related to the formation of

  20. Quasi-elastic scattering an alternative tool for mapping the fusion barriers for heavy-ion induced fusion reaction

    International Nuclear Information System (INIS)

    Behera, B.R.

    2016-01-01

    Heavy element synthesis through heavy-ion induced fusion reaction is an active field in contemporary nuclear physics. Exact knowledge of fusion barrier is one of the essential parameters for planning any experiments for heavy element production. Theoretically there are many models available to predict the exact barrier. Though these models are successful for predicting the fusion of medium mass nuclei, it somehow fails for predicting the exact location of barrier for fusion of heavy nuclei. Experimental determination of barrier for such reactions is required for future experiments for the synthesis of heavy elements. Traditionally fusion barrier is determined taking a double derivative of fusion excitation function. However, such method is difficult in case of fusion of heavy nuclei due to its very low fusion/capture cross section and its experimental complications. Alternatively fusion barrier can be determined by measuring the quasi-elastic cross section at backward angles. This method can be applied for determining the fusion barrier for the fusion of heavy nuclei. Experimental determination of fusion barrier by different methods and comparison of the fusion excitation function and quasi-elastic scattering methods for the determination of fusion barrier are reviewed. At IUAC, New Delhi recently a program has been started for the measurement of fusion barrier through quasi-elastic scattering methods. The experimental facility and the first results of the experiments carried out with this facility are presented. (author)