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Sample records for head drain line

  1. 241-AY-102 Leak Detection Pit Drain Line Inspection Report

    Energy Technology Data Exchange (ETDEWEB)

    Boomer, Kayle D. [Hanford Site (HNF), Richland, WA (United States); Engeman, Jason K. [Hanford Site (HNF), Richland, WA (United States); Gunter, Jason R. [Hanford Site (HNF), Richland, WA (United States); Joslyn, Cameron C. [Hanford Site (HNF), Richland, WA (United States); Vazquez, Brandon J. [Hanford Site (HNF), Richland, WA (United States); Venetz, Theodore J. [Hanford Site (HNF), Richland, WA (United States); Garfield, John S. [AEM Consulting, Richland, WA (United States)

    2014-01-20

    This document provides a description of the design components, operational approach, and results from the Tank AY-102 leak detection pit drain piping visual inspection. To perform this inspection a custom robotic crawler with a deployment device was designed, built, and operated by IHI Southwest Technologies, Inc. for WRPS to inspect the 6-inch leak detection pit drain line.

  2. Brain drain leads to more physicists heading to the US

    Science.gov (United States)

    Cartwright, Jon

    2010-01-01

    If budgets are too tight at home, academics often flock abroad in what is known as a "brain drain". But now a study by economists in the UK has revealed that elite physicists seem to be more mobile than ever. Having ana lysed the career paths of 158 of the world's most highly cited physicists, Andrew Oswald of the University of Warwick and colleagues found that half do not now work in the countries where they were born (Economic Journal 119 F231).

  3. Interaction between Engineered Cementitious Composites Lining and Foundation Subsurface Drain

    Directory of Open Access Journals (Sweden)

    Cleopatra Panganayi

    2011-01-01

    Full Text Available The effect of cyclic loads on the surface profiles of ECC linings cast on foundations comprising crushed stone and compacted soil was investigated. A geotextile was embedded between the crushed stone and ECC lining for some of the samples. After 28 days of water curing, the hardened surfaces were loaded and monitored for roughness and crack development by measuring surface levels and crack widths, respectively. Neither cracking nor significant variations in the lateral profiles were observed on all the samples for all the loads applied. However, significant variations which depended on the foundation types were observed in the vertical profiles. It was concluded that while ECC can resist cracking due to its high strain capacity, its flexibility causes ECC linings to assume the shape of the foundation material, which can increase the surface roughness at certain loading configurations.

  4. Determination of the crystalline structure of scale solids from the 16H evaporator gravity drain line to tank 38H

    Energy Technology Data Exchange (ETDEWEB)

    Oji, L. N. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-10-01

    August 2015, scale solids from the 16H Evaporator Gravity Drain Line (GDL) to the Tank 38H were delivered to SRNL for analysis. The desired analytical goal was to identify and confirm the crystalline structure of the scale material and determine if the form of the aluminosilicate mineral was consistent with previous analysis of the scale material from the GDL.

  5. Hydrography, HydroLine-The data set is a line feature containing streams, aqueducts, drains, and culverts. It consists of more than 580 segments representing natural surface water flow, as well as channeled water flow., Published in 2005, Davis County Government.

    Data.gov (United States)

    NSGIC Local Govt | GIS Inventory — Hydrography dataset current as of 2005. HydroLine-The data set is a line feature containing streams, aqueducts, drains, and culverts. It consists of more than 580...

  6. Doubled haploid inbred lines USVL048 and USVL131 of heading broccoli

    Science.gov (United States)

    Two inbred lines of heading broccoli (Brassica oleracea L. var. italica), designated USVL048 and USVL131, were released by the Agricultural Research Service of the U.S. Department of Agriculture in 2012. Both of the released lines are doubled haploids originally derived from another culture. As do...

  7. 46 CFR 45.157 - Scuppers and gravity drains.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Scuppers and gravity drains. 45.157 Section 45.157 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) LOAD LINES GREAT LAKES LOAD LINES Conditions of Assignment § 45.157 Scuppers and gravity drains. Scuppers and gravity deck drains from spaces...

  8. Set-up improvement in head and neck radiotherapy using a 3D off-line EPID-based correction protocol and a customised head and neck support.

    NARCIS (Netherlands)

    Lin, E.N.J.T. van; Vight, L.P. van der; Huizenga, H.; Kaanders, J.H.A.M.; Visser, A.G.

    2003-01-01

    PURPOSE: First, to investigate the set-up improvement resulting from the introduction of a customised head and neck (HN) support system in combination with a technologist-driven off-line correction protocol in HN radiotherapy. Second, to define margins for planning target volume definition,

  9. Cytotoxic effects of mistletoe (Viscum album L.) in head and neck squamous cell carcinoma cell lines.

    Science.gov (United States)

    Klingbeil, Ma Fátima G; Xavier, Flávia C A; Sardinha, Luiz R; Severino, Patricia; Mathor, Monica B; Rodrigues, Rodrigo V; Pinto, Décio S

    2013-11-01

    Head and neck squamous cell carcinoma is a complex disease with several etiologic factors and different molecular changes that may trigger certain events; it is also globally one of the most common malignancies in this topography. Extracts from Viscum album L. (VA) (mistletoe) have been used as adjuvant therapies with promising results in several types of cancer, mainly in European countries. In vitro studies have demonstrated that various types of VA may have cytotoxicity in carcinoma cells, activating the apoptotic cascade or leading cells to necrosis. This study aimed to verify the effects of three types of VA extracts (Iscador Qu Spezial, Iscador P and Iscador M) in squamous cell carcinoma of the tongue cell lines SCC9 and SCC25, not previously studied. A concentration of 0.3 mg/ml (IC50) of the drugs induced apoptosis, affecting gene expression and protein levels of AKT, PTEN and CYCLIN D1. It was concluded that VA extracts have a cytotoxic effect on SCC9 and SCC25 cell lines, but while SCC9 cell line was more resistant to the action of the drugs, Iscador Qu Spezial and Iscador M have higher cytotoxic potential in both cell lines compared to Iscador P.

  10. Containment vessel drain system

    Energy Technology Data Exchange (ETDEWEB)

    Harris, Scott G.

    2018-01-30

    A system for draining a containment vessel may include a drain inlet located in a lower portion of the containment vessel. The containment vessel may be at least partially filled with a liquid, and the drain inlet may be located below a surface of the liquid. The system may further comprise an inlet located in an upper portion of the containment vessel. The inlet may be configured to insert pressurized gas into the containment vessel to form a pressurized region above the surface of the liquid, and the pressurized region may operate to apply a surface pressure that forces the liquid into the drain inlet. Additionally, a fluid separation device may be operatively connected to the drain inlet. The fluid separation device may be configured to separate the liquid from the pressurized gas that enters the drain inlet after the surface of the liquid falls below the drain inlet.

  11. QTL Characterization of Fusarium Head Blight Resistance in CIMMYT Bread Wheat Line Soru#1.

    Directory of Open Access Journals (Sweden)

    Xinyao He

    Full Text Available Fusarium head blight (FHB resistant line Soru#1 was hybridized with the German cultivar Naxos to generate 131 recombinant inbred lines for QTL mapping. The population was phenotyped for FHB and associated traits in spray inoculated experiments in El Batán (Mexico, spawn inoculated experiments in Ås (Norway and point inoculated experiments in Nanjing (China, with two field trials at each location. Genotyping was performed with the Illumina iSelect 90K SNP wheat chip, along with a few SSR and STS markers. A major QTL for FHB after spray and spawn inoculation was detected on 2DLc, explaining 15-22% of the phenotypic variation in different experiments. This QTL remained significant after correction for days to heading (DH and plant height (PH, while another QTL for FHB detected at the Vrn-A1 locus on 5AL almost disappeared after correction for DH and PH. Minor QTL were detected on chromosomes 2AS, 2DL, 4AL, 4DS and 5DL. In point inoculated experiments, QTL on 2DS, 3AS, 4AL and 5AL were identified in single environments. The mechanism of resistance of Soru#1 to FHB was mainly of Type I for resistance to initial infection, conditioned by the major QTL on 2DLc and minor ones that often coincided with QTL for DH, PH and anther extrusion (AE. This indicates that phenological and morphological traits and flowering biology play important roles in resistance/escape of FHB. SNPs tightly linked to resistance QTL, particularly 2DLc, could be utilized in breeding programs to facilitate the transfer and selection of those QTL.

  12. Cytotoxic effect of Erythroxylum suberosum combined with radiotherapy in head and neck cancer cell lines

    Energy Technology Data Exchange (ETDEWEB)

    Macedo, Taysa B.C.; Torres, Hianne M.; Yamamoto-Silva, Fernanda Paula; Silva, Maria Alves G. [Universidade Federal de Goias (UFG), Goiania, GO (Brazil). Escola de Odontologia; Elias, Silvia T.; Silveira, Damaris; Magalhaes, Perola O.; Lofrano-Porto, Adriana; Guerra, Eliete N.S., E-mail: elieteneves@unb.br [Universidade de Brasilia (UnB), Brasilia, DF (Brazil). Faculdade de Ciencias da Saude

    2016-01-15

    The mouth and oropharynx cancer is the 6{sup th} most common type of cancer in the world. The treatment may involve surgery, chemotherapy and radiotherapy. More than 50% of drugs against cancer were isolated from natural sources, such as Catharanthus roseus and epipodophyllotoxin, isolated from Podophyllum. The biggest challenge is to maximize the control of the disease, while minimizing morbidity and toxicity to the surrounding normal tissues. The Erythroxylum suberosum is a common plant in the Brazilian Cerrado biome and is popularly known as 'cabelo-de-negro'. The objective of this study was to evaluate the cytotoxic activity of Erythroxylum suberosum plant extracts of the Brazilian Cerrado biome associated with radiotherapy in human cell lines of oral and hypopharynx carcinomas. Cells were treated with aqueous, ethanolic and hexanic extracts of Erythroxylum suberosum and irradiated at 4 Gy, 6 Gy and 8 Gy. Cytotoxicity was evaluated by MTT assay and the absorbance was measured at 570 nm in a Beckman Counter reader. Cisplatin, standard chemotherapy, was used as positive control. The use of Erythroxylum suberosum extracts showed a possible radiosensitizing effect in vitro for head and neck cancer. The cytotoxicity effect in the cell lines was not selective and it is very similar to the effect of standard chemotherapy. The aqueous extract of Erythroxylum suberosum, combined with radiotherapy was the most cytotoxic extract to oral and hypopharynx carcinomas. (author)

  13. Cytotoxic Effect of Erythroxylum suberosum Combined with Radiotherapy in Head and Neck Cancer Cell Lines.

    Science.gov (United States)

    Macedo, Taysa B C; Elias, Silvia T; Torres, Hianne M; Yamamoto-Silva, Fernanda Paula; Silveira, Dâmaris; Magalhães, Pérola O; Lofrano-Porto, Adriana; Guerra, Eliete N S; Silva, Maria Alves G

    2016-01-01

    The mouth and oropharynx cancer is the 6th most common type of cancer in the world. The treatment may involve surgery, chemotherapy and radiotherapy. More than 50% of drugs against cancer were isolated from natural sources, such as Catharanthus roseus and epipodophyllotoxin, isolated from Podophyllum. The biggest challenge is to maximize the control of the disease, while minimizing morbidity and toxicity to the surrounding normal tissues. The Erythroxylum suberosum is a common plant in the Brazilian Cerrado biome and is popularly known as "cabelo-de-negro". The objective of this study was to evaluate the cytotoxic activity of Erythroxylum suberosum plant extracts of the Brazilian Cerrado biome associated with radiotherapy in human cell lines of oral and hypopharynx carcinomas. Cells were treated with aqueous, ethanolic and hexanic extracts of Erythroxylum suberosum and irradiated at 4 Gy, 6 Gy and 8 Gy. Cytotoxicity was evaluated by MTT assay and the absorbance was measured at 570 nm in a Beckman Counter reader. Cisplatin, standard chemotherapy, was used as positive control. The use of Erythroxylum suberosum extracts showed a possible radiosensitizing effect in vitro for head and neck cancer. The cytotoxicity effect in the cell lines was not selective and it is very similar to the effect of standard chemotherapy. The aqueous extract of Erythroxylum suberosum, combined with radiotherapy was the most cytotoxic extract to oral and hypopharynx carcinomas.

  14. Effect of the coffee ingredient cafestol on head and neck squamous cell carcinoma cell lines

    Energy Technology Data Exchange (ETDEWEB)

    Kotowski, Ulana; Heiduschka, Gregor; Eckl-Dorna, Julia; Kranebitter, Veronika; Stanisz, Isabella; Brunner, Markus; Lill, Claudia; Thurnher, Dietmar [Medical University of Vienna, Department of Otorhinolaryngology, Head and Neck Surgery, Vienna (Austria); Seemann, Rudolf [Medical University of Vienna, Departement of Cranio-, Maxillofacial- and Oral Surgery, Vienna (Austria); Schmid, Rainer [Medical University of Vienna, Department of Radiotherapy, Vienna (Austria)

    2015-01-10

    Cafestol is a diterpene molecule found in coffee beans and has anticarcinogenic properties. The aim of the study was to examine the effects of cafestol in head and neck squamous cell carcinoma (HNSCC) cells. Three HNSCC cell lines (SCC25, CAL27 and FaDu) were treated with increasing doses of cafestol. Then combination experiments with cisplatin and irradiation were carried out. Drug interactions and possible synergy were calculated using the combination index analysis. Clonogenic assays were performed after irradiation with 2, 4, 6 and 8 Gy, respectively, and the rate of apoptosis was measured with flow cytometry. Treatment of HNSCC cells with cafestol leads to a dose-dependent reduction of cell viability and to induction of apoptosis. Combination with irradiation shows a reduction of clonogenic survival compared to each treatment method alone. In two of the cell lines a significant additive effect was observed. Cafestol is a naturally occurring effective compound with growth-inhibiting properties in head and neck cancer cells. Moreover, it leads to a significant inhibition of colony formation. (orig.) [German] Cafestol ist ein Diterpen, das in der Kaffeebohne vorkommt und antikanzerogene Eigenschaften besitzt. Ziel der Studie war, die Wirkung von Cafestol auf Kopf-Hals-Tumorzelllinien zu untersuchen. Drei Kopf-Hals-Tumorzelllinien (SCC25, CAL27 und FaDu) wurden mit steigenden Cafestol-Dosen behandelt. Anschliessend fanden Kombinationsexperimente mit Cisplatin und Bestrahlung statt. Die Wechselwirkung zwischen den Substanzen und moegliche synergistische Wirkungen wurden mit dem Combination-Index analysiert. Koloniebildungstests wurden nach Bestrahlung mit 2, 4, 6 und 8 Gy durchgefuehrt. Apoptose wurde mittels Durchflusszytometrie gemessen. Die Behandlung der Kopf-Hals-Tumorzelllinien mit Cafestol fuehrt zu einer dosisabhaengigen Abnahme des Zellueberlebens und zur Induktion von Apoptose. Die Kombination von Cafestol mit Bestrahlung zeigt eine geringere

  15. Cytotoxic Effect of Thiabendazole on Hn5 Head and Neck Squamous Cell Carcinoma Cell Line.

    Science.gov (United States)

    Abassi, Amir Jalal; Mohamadnia, Abdolreza; Parhiz, Seyed Alireza; Azizi Moghadam, Nahid; Bahrami, Naghmeh

    2017-09-01

    Evidence shows thiabendazole has the potential to inhibit angiogenesis in melanoma and fibrosarcoma; however, its effect on oral squamous cell carcinoma has not been previously studied. This study sought to assess the cytotoxic effects of thiabendazole on HN5 head and neck squamous carcinoma cell line. HN5 cell lines were exposed to different concentrations of thiabendazole (prepared from 99% pure powder) for 24, 48 and 72 hours. Cell viability was assessed by the methyl thiazol tetrazolium assay, and IC50 of thiabendazole was calculated. Cells were also exposed to different concentrations of thiabendazole for 48 hours to determine its effect on expression and transcription of vascular endothelial growth factor gene. Expression of vascular endothelial growth factor mRNA was assessed by real-time polymerase chain reaction. The vascular endothelial growth factor release was assessed by the enzyme-linked immunosorbent assay test. In all concentrations of thiabendazole except for 200 and 550μM, cell viability was significantly different at different time points (p< 0.05). At 48 and 72 hours, cell viability at all concentrations of thiabendazole (100-650μM) significantly decreased compared to the control group (zero concentration). In addition, cell viability significantly decreased with an increase in thiabendazole concentration. At 48 hours, expression of vascular endothelial growth factor mRNA was significantly lower in presence of 500μM thiabendazole compared to the control group (p< 0.001) and release of vascular endothelial growth factor was inhibited in a dose-dependent manner. Thiabendazole inhibited the proliferation of HN5 cells in a dose-dependent and time-dependent manner. It also inhibited the expression of vascular endothelial growth factor gene.

  16. Molecular and pathological characterization of Fusarium solani species complex infection in the head and lateral line system of Sphyrna lewini.

    Science.gov (United States)

    Pirarat, Nopadon; Sahatrakul, Komsil; Lacharoje, Sitthichok; Lombardini, Eric; Chansue, Nantarika; Techangamsuwan, Somporn

    2016-08-09

    A severe fungal infection affecting the head and lateral line system was diagnosed in 7 captive scalloped hammerhead sharks Sphyrna lewini in an aquarium in Thailand. Extensive and severe necrotizing cellulitis was consistently observed microscopically along the cephalic and lateral line canals in conjunction with positive fungal cultures for Fusarium sp. Molecular phylogenetic analysis was performed from 3 isolates based on the nucleotide sequences containing internally transcribed spacer (ITS) and a portion of 5.8S and 28S rDNA. The fungus was highly homologous (100%) and closely related to F. solani species complex 2 (FSSC 2), which belongs to Clade 3 of the FSSC. Our results illustrate the histopathological findings and expand upon our knowledge of the prevalence of invasive fusariosis in the head and lateral line system of hammerhead sharks.

  17. Comparative miRNAs analysis of Two contrasting broccoli inbred lines with divergent head-forming capacity under temperature stress.

    Science.gov (United States)

    Chen, Chi-Chien; Fu, Shih-Feng; Norikazu, Monma; Yang, Yau-Wen; Liu, Yu-Ju; Ikeo, Kazuho; Gojobori, Takashi; Huang, Hao-Jen

    2015-12-01

    MicroRNAs (miRNAs) play a vital role in growth, development, and stress response at the post-transcriptional level. Broccoli (Brassica oleracea L. var italic) is an important vegetable crop, and the yield and quality of broccoli are decreased by heat stress. The broccoli inbred lines that are capable of producing head at high temperature in summer are unique varieties in Taiwan. However, knowledge of miRNAomes during the broccoli head formation under heat stress is limited. In this study, molecular characterization of two nearly isogenic lines with contrasting head-forming capacity was investigated. Head-forming capacity was better for heat-tolerant (HT) than heat-sensitive (HS) broccoli under heat stress. By deep sequencing and computational analysis, 20 known miRNAs showed significant differential expression between HT and HS genotypes. According to the criteria for annotation of new miRNAs, 24 novel miRNA sequences with differential expression between the two genotypes were identified. To gain insight into functional significance, 213 unique potential targets of these 44 differentially expressed miRNAs were predicted. These targets were implicated in shoot apical development, phase change, response to temperature stimulus, hormone and energy metabolism. The head-forming capacity of the unique HT line was related to autonomous regulation of Bo-FT genes and less expression level of heat shock protein genes as compared to HS. For the genotypic comparison, a set of miRNAs and their targets had consistent expression patterns in various HT genotypes. This large-scale characterization of broccoli miRNAs and their potential targets is to unravel the regulatory roles of miRNAs underlying heat-tolerant head-forming capacity.

  18. Puppy line, metaphyseal sclerosis, and caudolateral curvilinear and circumferential femoral head osteophytes in early detection of canine hip dysplasia.

    Science.gov (United States)

    Risler, Amanda; Klauer, Julia M; Keuler, Nicholas S; Adams, William M

    2009-01-01

    Ventrodorsal extended hip radiographs were analyzed from Foxhounds, Irish setters, Greyhounds, and Labrador retrievers radiographed four to seven times between 8 and 110 weeks of age. Occurrence in these 91 dogs of a puppy line, an ill-defined zone of proximal femoral metaphyseal sclerosis, a femoral neck linear sclerosis, or circumferential linear femoral head osteophytosis at 15-17 weeks of age were compared with hip joint laxity, as measured by distraction index, and to later findings of caudal curvilinear femoral neck osteophytes, circumferential femoral head osteophytes, hip incongruity consistent with hip dysplasia and degenerative joint disease by 52 weeks of age. A puppy line and/or femoral metaphyseal sclerosis was common at 15-17 weeks of age for dogs at mimimal risk (Greyhounds) and high risk (Foxhounds) of developing early degenerative joint disease associated with canine hip dysplasia. Though 44% of Greyhound hips had puppy lines and 28% had femoral metaphyseal sclerosis at 15-17 weeks of age, no Greyhound had a caudolateral curvilinear osteophyte or circumferential femoral head osteophyte at 24-27 or 52 weeks of age. No significant relationship was found between occurrence of a puppy line, a circumferential femoral head osteophyte or femoral metaphyseal sclerosis at 15-17 weeks and canine hip dysplasia or degenerative joint disease incidence at 42-52 weeks. Presence of a caudolateral curvilinear osteophyte in at least one hip at 24-27 weeks was significantly related to the diagnosis of canine hip dysplasia by 42-52 weeks. When both a caudolateral curvilinear osteophyte and a circumferential femoral head osteophyte were present in a hip at 24-27 weeks, degenerative joint disease was evident in all such hips by 42-52 weeks of age.

  19. Integration of high-risk human papillomavirus into cellular cancer-related genes in head and neck cancer cell lines.

    Science.gov (United States)

    Walline, Heather M; Goudsmit, Christine M; McHugh, Jonathan B; Tang, Alice L; Owen, John H; Teh, Bin T; McKean, Erin; Glover, Thomas W; Graham, Martin P; Prince, Mark E; Chepeha, Douglas B; Chinn, Steven B; Ferris, Robert L; Gollin, Susanne M; Hoffmann, Thomas K; Bier, Henning; Brakenhoff, Ruud; Bradford, Carol R; Carey, Thomas E

    2017-05-01

    Human papillomavirus (HPV)-positive oropharyngeal cancer is generally associated with excellent response to therapy, but some HPV-positive tumors progress despite aggressive therapy. The purpose of this study was to evaluate viral oncogene expression and viral integration sites in HPV16- and HPV18-positive squamous cell carcinoma lines. E6/E7 alternate transcripts were assessed by reverse transcriptase-polymerase chain reaction (RT-PCR). Detection of integrated papillomavirus sequences (DIPS-PCR) and sequencing identified viral insertion sites and affected host genes. Cellular gene expression was assessed across viral integration sites. All HPV-positive cell lines expressed alternate HPVE6/E7 splicing indicative of active viral oncogenesis. HPV integration occurred within cancer-related genes TP63, DCC, JAK1, TERT, ATR, ETV6, PGR, PTPRN2, and TMEM237 in 8 head and neck squamous cell carcinoma (HNSCC) lines but UM-SCC-105 and UM-GCC-1 had only intergenic integration. HPV integration into cancer-related genes occurred in 7 of 9 HPV-positive cell lines and of these 6 were from tumors that progressed. HPV integration into cancer-related genes may be a secondary carcinogenic driver in HPV-driven tumors. © 2017 Wiley Periodicals, Inc. Head Neck 39: 840-852, 2017. © 2017 Wiley Periodicals, Inc.

  20. Drain opener poisoning

    Science.gov (United States)

    Drain opener poisoning can cause symptoms in many parts of the body. BLOOD Severe change in acid level of blood (pH balance), which leads to damage in all of the body organs EYES, EARS, NOSE, AND THROAT Burns to the eyes, which ...

  1. Drain for Gain

    NARCIS (Netherlands)

    Ritzema, H.P.

    2016-01-01

    At present, about 299 Mha (or 18%) of the arable and permanent cropped areas worldwide are irrigated and, although drainage is an important component of irrigation, only 22% of these irrigated lands are drained. As a consequence, salinity and waterlogging problems affect about 10-16% of these

  2. Closed suction drain with bulb

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/patientinstructions/000039.htm Closed suction drain with bulb To use the sharing features on this page, please enable JavaScript. A closed suction drain is used to remove fluids that build ...

  3. Analysis of apoptotic cell death following irradiation in SCC malignant cell lines derived from the head and neck

    Energy Technology Data Exchange (ETDEWEB)

    Uno, Masako [Kawasaki Medical School, Kurashiki, Okayama (Japan)

    2000-07-01

    To explore radiation-resistancy in head and neck squamous cell carcinoma (HNSCC), two HNSCC lines, KB derived from the oral floor and HEp-2 from the larynx, were used to clarify the cellular biological alterations related to apoptotic cell death induced by irradiation. Both cell lines revealed ultrastructual apoptotic morphological changes and showed dose- and time- dependent increase in to the apoptotic fraction examined by the TUNEL method using flow cytometry. The KB cells showed time- and dose-dependent upregulation of membrane Fas (mFas) expression after irradiation. Analysis of alteration in the mRNA expression levels of apoptosis-related genes demonstrated slight upregulation of Fas, Flice, Bax, and TNFRl genes in KB cells and of the Fas ligand gene in HEp-2 cells. In addition, the DcR3 gene, which completes Fas-Fas ligand binding and inhibits Fas-mediated apoptosis, was upregulated in KB cells after irradiation. Based on these results, Fas-mediated apoptotic pathway may be involved in irradiation- induced apoptosis via p53 upregulation. Further investigations are required to resolve questions regarding the radiation-resistancy which often occurs after radiotherapy for head and neck malignancies. (author)

  4. AFFERENT RESPONSE OF A HEAD CANAL NEUROMAST OF THE RUFF (ACERINA-CERNUA) LATERAL LINE

    NARCIS (Netherlands)

    WUBBELS, RJ

    1. The fourth neuromast of the supra-orbital canal of the ruff lateral line is innervated by 300-400 fibres. 2. Afferent activity of 46 fibres was investigated as a function of stimulus amplitude and of stimulus frequency. 3. The dynamic range of the fibres exceeded 30 dB. 4. The gain with respect

  5. Distinct population of highly malignant cells in a head and neck squamous cell carcinoma cell line established by xenograft model

    Directory of Open Access Journals (Sweden)

    Jan Chia-Ing

    2009-11-01

    Full Text Available Abstract The progression and metastasis of solid tumors, including head and neck squamous cell carcinoma (HNSCC, have been related to the behavior of a small subpopulation of cancer stem cells. Here, we have established a highly malignant HNSCC cell line, SASVO3, from primary tumors using three sequential rounds of xenotransplantation. SASVO3 possesses enhanced tumorigenic ability both in vitro and in vivo. Moreover, SASVO3 exhibits properties of cancer stem cells, including that increased the abilities of sphere-forming, the number of side population cells, the potential of transplanted tumor growth and elevated expression of the stem cell marker Bmi1. Injection of SASVO3 into the tail vein of nude mice resulted in lung metastases. These results are consistent with the postulate that the malignant and/or metastasis potential of HNSCC cells may reside in a stem-like subpopulation.

  6. Anticancer activity of Ashwagandha against human head and neck cancer cell lines.

    Science.gov (United States)

    Lee, Haeng-Eun; Shin, Ji-Ae; Jeong, Joseph H; Jeon, Jae-Gyu; Lee, Min-Ho; Cho, Sung-Dae

    2016-03-01

    The aim of this study was to determine the apoptotic activity of methanol extract of Ashwagandha (MEAG) and in human head and neck squamous cell carcinoma (HNSCC) cells and to investigate the underlying mechanisms. We investigated the effects of MEAG on programmed cell death in HNSCC cells using a Live/Dead assay, detection of nuclear morphologic changes, Mitotracker, siRNA knockdown, and RT-PCR. Treatment with MEAG showed dose-dependent growth-inhibitory activity that attribute to caspase-dependent apoptosis. Loss of mitochondrial membrane potential, release of cytochrome c, and activation of caspase 9 suggested that MEAG leads to activation of mitochondria-mediated apoptosis. MEAG selectively upregulated the expression of Bim protein at the transcriptional level and induced the translocation of Bim into the mitochondria. Knockdown of Bim by siRNA partially blocked MEAG-mediated apoptosis. MEAG also caused an increase in truncated Bid (t-Bid), cleaved caspase-8, and death receptor 5 (DR5). Interestingly, withaferin A (WA), a bioactive component of MEAG, clearly induced apoptosis accompanied by upregulation of Bim, t-Bid, caspase-8, and DR5 similar to the effects of MEAG. These suggest that MEAG and WA may be potential natural materials for the treatment of HNSCC. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  7. Afatinib versus methotrexate as second-line treatment in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck progressing on or after platinum-based therapy (LUX-Head & Neck 1)

    DEFF Research Database (Denmark)

    Machiels, Jean-Pascal H; Haddad, Robert I; Fayette, Jérôme

    2015-01-01

    BACKGROUND: Patients with recurrent or metastatic squamous-cell carcinoma of the head and neck (HNSCC) progressing after first-line platinum regimens have a poor prognosis and few treatment options. Afatinib, an irreversible ERBB family blocker, has shown efficacy in a phase 2 study in this setti...

  8. The effect of cilengitide in combination with irradiation and chemotherapy in head and neck squamous cell carcinoma cell lines

    Energy Technology Data Exchange (ETDEWEB)

    Heiduschka, G. [Medical University of Vienna, Department of Otorhinolaryngology, Head and Neck Surgery, Comprehensive Cancer Center, Vienna (Austria); Medical University of Vienna, Clinical Pharmacology, Vienna (Austria); Lill, C.; Schneider, S.; Kotowski, U.; Thurnher, D. [Medical University of Vienna, Department of Otorhinolaryngology, Head and Neck Surgery, Comprehensive Cancer Center, Vienna (Austria); Seemann, R. [Medical University of Vienna, Craniomaxillofacial and Oral Surgery, Vienna (Austria); Kornek, G. [Medical University of Vienna, Internal Medicine, Vienna (Austria); Schmid, R. [Medical University of Vienna, Radiotherapy and Radiobiology, Vienna (Austria)

    2014-05-15

    Integrins are highly attractive targets in oncology due to their involvement in angiogenesis in a wide spectrum of cancer entities. Among several integrin inhibitors under clinical evaluation, cilengitide is the most promising compound. However, little is known about the cellular processes induced during cilengitide therapy in combination with irradiation and cisplatin in head and neck squamous cell carcinoma (HNSCC). The cytostatic effect of cilengitide was assessed by proliferation assay in the three HNSCC cell lines SCC25, FaDu and CAL27. Combination experiments with cisplatin and irradiation were performed. Possible synergistic effects were calculated in combination index (CI) analyses. Colony forming inhibition was investigated in clonogenic assays. Real-time PCR arrays were used to evaluate target protein gene expression patterns. Flow cytometry was used to detect apoptosis. Used alone, cilengitide has only minor cytotoxic effects in HNSCC cell lines. However, combination with cisplatin resulted in synergistic growth inhibition in all three cell lines. Irradiation showed synergism in short-term experiments and in colony forming assays, an additive effect was detected. Real-time PCR assay detected downregulation of the antiapoptotic protein Bcl-2 after exposure of cells to cilengitide. Cilengitide in combination with cisplatin and irradiation may be a feasible option for the treatment of patients with head and neck cancer. However, further investigations are required to understand the exact mechanism that leads to synergistic cytotoxicity. (orig.) [German] Durch ihre Rolle bei der Angiogenese sind Integrine ein attraktives Ziel in der onkologischen Forschung. Der derzeit vielversprechendste Inhibitor dieser Molekuele ist Cilengitide, welches bereits in klinischen Studien getestet wird. Dennoch ist erst wenig ueber die zellulaeren Vorgaenge bekannt, welche durch Cilengitide in Kopf-Hals-Karzinomen (HNSCC) insbesondere in Kombination mit Strahlentherapie und

  9. Alpha-2 Heremans Schmid Glycoprotein (AHSG) Modulates Signaling Pathways in Head and Neck Squamous Cell Carcinoma Cell Line SQ20B

    OpenAIRE

    Thompson, Pamela D.; Sakwe, Amos; Koumangoye, Rainelli; Yarbrough, Wendell G.; Ochieng, Josiah; Marshall, Dana R.

    2013-01-01

    This study was performed to identify the potential role of Alpha-2 Heremans Schmid Glycoprotein (AHSG) in Head and Neck Squamous Cell Carcinoma (HNSCC) tumorigenesis using an HNSCC cell line model. HNSCC cell lines are unique among cancer cell lines, in that they produce endogenous AHSG and do not rely, solely, on AHSG derived from serum. To produce our model, we performed a stable transfection to down-regulate AHSG in the HNSCC cell line SQ20B, resulting in three SQ20B sublines, AH50 with 50...

  10. Optimal shapes for best draining

    Science.gov (United States)

    Sherwood, J. D.

    2009-11-01

    The container shape that minimizes the volume of draining fluid remaining on the walls of the container after it has been emptied from its base is determined. The film of draining fluid is assumed to wet the walls of the container, and is sufficiently thin so that its curvature may be neglected. Surface tension is ignored. The initial value problem for the thickness of a film of Newtonian fluid is studied, and is shown to lead asymptotically to a similarity solution. From this, and from equivalent solutions for power-law fluids, the volume of the residual film is determined. The optimal container shape is not far from hemispherical, to minimize the surface area, but has a conical base to promote draining. The optimal shape for an axisymmetric mixing vessel, with a hole at the center of its base for draining, is also optimal when inverted in the manner of a washed wine glass inverted and left to drain.

  11. Plumbing the brain drain.

    Science.gov (United States)

    Saravia, Nancy Gore; Miranda, Juan Francisco

    2004-08-01

    Opportunity is the driving force of migration. Unsatisfied demands for higher education and skills, which have been created by the knowledge-based global economy, have generated unprecedented opportunities in knowledge-intensive service industries. These multi-trillion dollar industries include information, communication, finance, business, education and health. The leading industrialized nations are also the focal points of knowledge-intensive service industries and as such constitute centres of research and development activity that proactively draw in talented individuals worldwide through selective immigration policies, employment opportunities and targeted recruitment. Higher education is another major conduit of talent from less-developed countries to the centres of the knowledge-based global economy. Together career and educational opportunities drive "brain drain and recirculation". The departure of a large proportion of the most competent and innovative individuals from developing nations slows the achievement of the critical mass needed to generate the enabling context in which knowledge creation occurs. To favourably modify the asymmetric movement and distribution of global talent, developing countries must implement bold and creative strategies that are backed by national policies to: provide world-class educational opportunities, construct knowledge-based research and development industries, and sustainably finance the required investment for these strategies. Brazil, China and India have moved in this direction, offering world-class education in areas crucial to national development, such as biotechnology and information technology, paralleled by investments in research and development. As a result, only a small proportion of the most highly educated individuals migrate from these countries, and research and development opportunities employ national talent and even attract immigrants.

  12. Long-term growth comparison studies of FBS and FBS alternatives in six head and neck cell lines

    Science.gov (United States)

    Wu, Chung-Chun; Fang, Chia-Lang; Chen, Wei-Yu; Chen, Chi-Long

    2017-01-01

    Fetal bovine serum (FBS) is depended upon by investigators as an indispensable supplement in cell and tissue culture systems. Due to increased demand and limited availability, the price of FBS has increased by greater than 300% in the past few years. In addition, there are ethical and scientific controversies about the collection and use of FBS in culture systems. In response to the shortage of FBS, many FBS alternative serum products have been developed. Although many have claimed comparable performance to FBS, their support of long-term cell growth and effects on cell phenotype have not been revealed. In this study, we examined the performances of six bovine calf serum-based FBS alternatives in six head and neck cell lines and compared them with FBS. The results indicate that some of these sera had growth promoting capabilities comparable or superior to that of FBS. Additionally, these alternative sera supported long-term (30 passages) growth of tested cells and exhibited plating efficiencies comparable to that of FBS. Cells cultured in alternative sera also exhibited comparable anchorage-independent growth and similar drug inhibition responses in FBS. Still, caution should be taken in choosing suitable sera given that changes in cell morphology and variations in chemotactic responses were noted for cells maintained in certain sera. These FBS alternatives are more readily available, cost less, and are associated with less ethical concerns, thus making them attractive alternatives to FBS in cell culture systems. PMID:28591207

  13. Long-term growth comparison studies of FBS and FBS alternatives in six head and neck cell lines.

    Directory of Open Access Journals (Sweden)

    Chih-Yeu Fang

    Full Text Available Fetal bovine serum (FBS is depended upon by investigators as an indispensable supplement in cell and tissue culture systems. Due to increased demand and limited availability, the price of FBS has increased by greater than 300% in the past few years. In addition, there are ethical and scientific controversies about the collection and use of FBS in culture systems. In response to the shortage of FBS, many FBS alternative serum products have been developed. Although many have claimed comparable performance to FBS, their support of long-term cell growth and effects on cell phenotype have not been revealed. In this study, we examined the performances of six bovine calf serum-based FBS alternatives in six head and neck cell lines and compared them with FBS. The results indicate that some of these sera had growth promoting capabilities comparable or superior to that of FBS. Additionally, these alternative sera supported long-term (30 passages growth of tested cells and exhibited plating efficiencies comparable to that of FBS. Cells cultured in alternative sera also exhibited comparable anchorage-independent growth and similar drug inhibition responses in FBS. Still, caution should be taken in choosing suitable sera given that changes in cell morphology and variations in chemotactic responses were noted for cells maintained in certain sera. These FBS alternatives are more readily available, cost less, and are associated with less ethical concerns, thus making them attractive alternatives to FBS in cell culture systems.

  14. Characterization and classification of one new cytoplasmic male sterility (CMS) line based on morphological, cytological and molecular markers in non-heading Chinese cabbage (Brassica rapa L.).

    Science.gov (United States)

    Heng, Shuangping; Shi, Dianyi; Hu, Zhenhua; Huang, Tao; Li, Jinping; Liu, Liyan; Xia, Chunxiu; Yuan, Zhenzhen; Xu, Yuejin; Fu, Tingdong; Wan, Zhengjie

    2015-09-01

    A new non-heading Chinese cabbage CMS line M119A was characterized and specific molecular markers were developed to classify different CMS types. One new non-heading Chinese cabbage (Brassica rapa L.) cytoplasmic male sterile (CMS) line M119A was obtained by interspecific crosses between the recently discovered hau CMS line of Brassica juncea and B. rapa. Furthermore, the line was characterized and compared with other five isonuclear-alloplasmic CMS lines. The M119A line produced six stamens without pollen and only two stamen fused together in fewer flowers. Tissue section indicated that anther abortion in M119A may have occurred during differentiation of the archesporial cells without pollen sac. All the six CMS lines were grouped into three types based on the presence of three PCR fragments of 825, 465 and 772 bp amplified with different mitochondrial genes specific primers. The 825-bp fragment was amplified both in 09-10A and H201A using the specific primer pair P-orf224-atp6, and showed 100 % identity with the mitochondrial gene of pol CMS. The 465-bp fragment was amplified in 30A and 105A using the primer pair P-orf138 and shared 100 % identity with the mitochondrial gene of ogu CMS. The 772-bp fragment was amplified in M119A and H203A using the primer pair P-orf288 and showed 100 % identity with the mitochondrial gene of hau CMS. Therefore, these markers could efficiently distinguish different types of isonuclear-alloplasmic CMS lines of non-heading Chinese cabbage, which were useful for improving the efficiency of cross-breeding and heterosis utilization in cruciferous vegetables.

  15. Drain versus No Drain after Thyroidectomy: A prospective ...

    African Journals Online (AJOL)

    Background: Drains have been traditionally used routinely after thyroidectomy despite limited evidence to suggest any benefit. We conducted a prospective randomized clinical study to evaluate the necessity of drainage after thyroid surgery. Methods: This was a prospective randomized clinical study which was conducted ...

  16. Hypomethylation of LINE-1, and not centromeric SAT-α, is associated with centromeric instability in head and neck squamous cell carcinoma.

    Science.gov (United States)

    Martínez, Jorge García; Pérez-Escuredo, Jhudit; Castro-Santos, Patricia; Marcos, César Alvarez; Pendás, José Luis Llorente; Fraga, Mario F; Hermsen, Mario A

    2012-08-01

    Head and neck squamous cell carcinoma (HNSCC) is a tumour type that generally carries very complex chromosomal aberrations. An interesting feature is the elevated occurrence (58 %) of whole arm translocations and isochromosomes, resulting from breakage and illegitimate recombination in centromeric or pericentromeric regions. We hypothesized that alterations in DNA methylation may play a role in the breakage of centromeric repeat sequences in these tumours. We studied the DNA methylation status of global repeats (LINE-1), subtelomeric repeats (D4Z4) and centromeric repeats (SAT-α) in relation to centromeric instability in a series of HNSCC cancer cell lines and primary tumours. We analysed the methylation status by pyrosequencing and the chromosomal aberrations by microarray CGH. We found a significant association between centromeric instability and hypomethylation of LINE-1, but not D4Z4 and SAT-α. These data suggest that centromeric instability is associated with genomic DNA hypomethylation only when occurring at specific DNA repeat sequences.

  17. Alpha-2 Heremans Schmid Glycoprotein (AHSG) Modulates Signaling Pathways in Head and Neck Squamous Cell Carcinoma Cell Line SQ20B

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, Pamela D.; Sakwe, Amos [Department of Biochemistry and Cancer Biology, Meharry Medical College, Nashville, TN 37208 (United States); Koumangoye, Rainelli [Division of Surgical Oncology and Endocrine Surgery, Vanderbilt University Medical Center, Nashville, TN 37232 (United States); Yarbrough, Wendell G. [Division of Otolaryngology, Departments of Surgery and Pathology and Yale Cancer Center, Yale University, New Haven, CT 06520 (United States); Ochieng, Josiah [Department of Biochemistry and Cancer Biology, Meharry Medical College, Nashville, TN 37208 (United States); Marshall, Dana R., E-mail: dmarshall@mmc.edu [Department of Pathology, Anatomy and Cell Biology, Meharry Medical College, Nashville, TN 37208 (United States)

    2014-02-15

    This study was performed to identify the potential role of Alpha-2 Heremans Schmid Glycoprotein (AHSG) in Head and Neck Squamous Cell Carcinoma (HNSCC) tumorigenesis using an HNSCC cell line model. HNSCC cell lines are unique among cancer cell lines, in that they produce endogenous AHSG and do not rely, solely, on AHSG derived from serum. To produce our model, we performed a stable transfection to down-regulate AHSG in the HNSCC cell line SQ20B, resulting in three SQ20B sublines, AH50 with 50% AHSG production, AH20 with 20% AHSG production and EV which is the empty vector control expressing wild-type levels of AHSG. Utilizing these sublines, we examined the effect of AHSG depletion on cellular adhesion, proliferation, migration and invasion in a serum-free environment. We demonstrated that sublines EV and AH50 adhered to plastic and laminin significantly faster than the AH20 cell line, supporting the previously reported role of exogenous AHSG in cell adhesion. As for proliferative potential, EV had the greatest amount of proliferation with AH50 proliferation significantly diminished. AH20 cells did not proliferate at all. Depletion of AHSG also diminished cellular migration and invasion. TGF-β was examined to determine whether levels of the TGF-β binding AHSG influenced the effect of TGF-β on cell signaling and proliferation. Whereas higher levels of AHSG blunted TGF-β influenced SMAD and ERK signaling, it did not clearly affect proliferation, suggesting that AHSG influences on adhesion, proliferation, invasion and migration are primarily due to its role in adhesion and cell spreading. The previously reported role of AHSG in potentiating metastasis via protecting MMP-9 from autolysis was also supported in this cell line based model system of endogenous AHSG production in HNSCC. Together, these data show that endogenously produced AHSG in an HNSCC cell line, promotes in vitro cellular properties identified as having a role in tumorigenesis. Highlights: • Head

  18. LINES

    Directory of Open Access Journals (Sweden)

    Minas Bakalchev

    2015-10-01

    Full Text Available The perception of elements in a system often creates their interdependence, interconditionality, and suppression. The lines from a basic geometrical element have become the model of a reductive world based on isolation according to certain criteria such as function, structure, and social organization. Their traces are experienced in the contemporary world as fragments or ruins of a system of domination of an assumed hierarchical unity. How can one release oneself from such dependence or determinism? How can the lines become less “systematic” and forms more autonomous, and less reductive? How is a form released from modernistic determinism on the new controversial ground? How can these elements or forms of representation become forms of action in the present complex world? In this paper, the meaning of lines through the ideas of Le Corbusier, Leonidov, Picasso, and Hitchcock is presented. Spatial research was made through a series of examples arising from the projects of the architectural studio “Residential Transformations”, which was a backbone for mapping the possibilities ranging from playfulness to exactness, as tactics of transformation in the different contexts of the contemporary world.

  19. Antitumoral effect of PLK-1-inhibitor BI2536 in combination with cisplatin and docetaxel in squamous cell carcinoma cell lines of the head and neck

    Science.gov (United States)

    WAGENBLAST, JENS; HIRTH, DANIEL; ECKARDT, ANNE; LEINUNG, MARTIN; DIENSTHUBER, MARC; STÖVER, TIMO; HAMBEK, MARKUS

    2013-01-01

    Inhibition of the polo-like-kinase-1 (PLK-1) has been shown to be effective in several haematological and solid tumor models. In this systemic in vitro study, the antitumor effect of BI2536, a small molecule inhibitor of PLK-1, in combination with cisplatin and docetaxel was examined in nine squamous cell carcinoma cell lines, most of which had a head and neck origin (SCCHN). Dose escalation studies were conducted with nine SCCHN cell lines using BI2536, cisplatin and docetaxel in cell line-specific concentrations. Growth inhibitory and proapoptotic effects were measured quantitatively using cytohistology and a Human Apoptose Array kit. BI2536 in combination with cisplatin and docetaxel showed a markedly higher antiproliferative and apoptotic activity in the SCCHN cell lines investigated (P≤0.008), compared with single agent cisplatin or docetaxel alone. The findings of this study showed that the addition of PLK-1-inhibitor BI2536 to conventional chemotherapeutic drugs led to a statistically higher antiproliferative and apoptotic effect in SCCHN cell lines compared with cisplatin or docetaxel alone. Inaugurating BI2536 in the clinical setting might enhance the antitumoral activity of conventional drugs, possibly leading to less toxic side effects of cancer therapy. PMID:24649162

  20. State waste discharge permit application, 200-E chemical drain field

    Energy Technology Data Exchange (ETDEWEB)

    1994-06-01

    As part of the Hanford Federal Facility Agreement and Consent Order negotiations (Ecology et al. 1994), the US Department of Energy, Richland Operations Office, the US Environmental Protection Agency, and the Washington State Department of Ecology agreed that liquid effluent discharges to the ground on the Hanford Site which affect groundwater or have the potential to affect ground would be subject to permitting under the structure of Chapter 173-216 (or 173-218 where applicable) of the Washington Administrative Code, the State Waste Discharge Permit Program. As a result of this decision, the Washington State Department of Ecology and the US Department of Energy, Richland Operations Office entered into Consent Order No. DE 91NM-177, (Ecology and DOE-RL 1991). The Consent Order No. DE 91NM-177 requires a series of permitting activities for liquid effluent discharges. This document presents the State Waste Discharge Permit (SWDP) application for the 200-E Chemical Drain Field. Waste water from the 272-E Building enters the process sewer line directly through a floor drain, while waste water from the 2703-E Building is collected in two floor drains, (north and south) that act as sumps and are discharged periodically. The 272-E and 2703-E Buildings constitute the only discharges to the process sewer line and the 200-E Chemical Drain Field.

  1. Measurements of electric field intensity under 750 kV over head lines in an orchard zone

    Energy Technology Data Exchange (ETDEWEB)

    Aleksandrov, G.N.; Kashina, V.A.; Lisochkina, T.V.; Podporkin, G.V.

    1980-01-01

    The maximum electric field intensity was found to take place in the middle of the space between the rows of apple trees and did not exceed 3 kV/m. The orchard layout and the intensity both through the orchard and under the lines where no trees grew (max intensity 10 kV/m) are given. Unpleasant sensations were experienced in the place where no trees grew due to discharges on contact with plants; the discharge currents in the orchard were too low to feel. Determining the suitability of using trees to ensure ecological safety of extrahigh and ultrahigh voltage overhead lines passing near cities is discussed.

  2. Pretreatment microRNA Expression Impacting on Epithelial-to-Mesenchymal Transition Predicts Intrinsic Radiosensitivity in Head and Neck Cancer Cell Lines and Patients.

    Science.gov (United States)

    de Jong, Monique C; Ten Hoeve, Jelle J; Grénman, Reidar; Wessels, Lodewyk F; Kerkhoven, Ron; Te Riele, Hein; van den Brekel, Michiel W M; Verheij, Marcel; Begg, Adrian C

    2015-12-15

    Predominant causes of head and neck cancer recurrence after radiotherapy are rapid repopulation, hypoxia, fraction of cancer stem cells, and intrinsic radioresistance. Currently, intrinsic radioresistance can only be assessed by ex vivo colony assays. Besides being time-consuming, colony assays do not identify causes of intrinsic resistance. We aimed to identify a biomarker for intrinsic radioresistance to be used before start of treatment and to reveal biologic processes that could be targeted to overcome intrinsic resistance. We analyzed both microRNA and mRNA expression in a large panel of head and neck squamous cell carcinoma (HNSCC) cell lines. Expression was measured on both irradiated and unirradiated samples. Results were validated using modified cell lines and a series of patients with laryngeal cancer. miRs, mRNAs, and gene sets that correlated with resistance could be identified from expression data of unirradiated cells. The presence of epithelial-to-mesenchymal transition (EMT) and low expression of miRs involved in the inhibition of EMT were important radioresistance determinants. This finding was validated in two independent cell line pairs, in which the induction of EMT reduced radiosensitivity. Moreover, low expression of the most important miR (miR-203) was shown to correlate with local disease recurrence after radiotherapy in a series of patients with laryngeal cancer. These findings indicate that EMT and low expression of EMT-inhibiting miRs, especially miR-203, measured in pretreatment material, causes intrinsic radioresistance of HNSCC, which could enable identification and treatment modification of radioresistant tumors. Clin Cancer Res; 21(24); 5630-8. ©2015 AACR. ©2015 American Association for Cancer Research.

  3. Non-musicians also have a piano in the head: evidence for spatial-musical associations from line bisection tracking.

    Science.gov (United States)

    Hartmann, Matthias

    2017-02-01

    The spatial representation of ordinal sequences (numbers, time, tones) seems to be a fundamental cognitive property. While an automatic association between horizontal space and pitch height (left-low pitch, right-high pitch) is constantly reported in musicians, the evidence for such an association in non-musicians is mixed. In this study, 20 non-musicians performed a line bisection task while listening to irrelevant high- and low-pitched tones and white noise (control condition). While pitch height had no influence on the final bisection point, participants' movement trajectories showed systematic biases: When approaching the line and touching the line for the first time (initial bisection point), the mouse cursor was directed more rightward for high-pitched tones compared to low-pitched tones and noise. These results show that non-musicians also have a subtle but nevertheless automatic association between pitch height and the horizontal space. This suggests that spatial-musical associations do not necessarily depend on constant sensorimotor experiences (as it is the case for musicians) but rather reflect the seemingly inescapable tendency to represent ordinal information on a horizontal line.

  4. Macrolide Antibiotics Exhibit Cytotoxic Effect under Amino Acid-Depleted Culture Condition by Blocking Autophagy Flux in Head and Neck Squamous Cell Carcinoma Cell Lines

    Science.gov (United States)

    Hirasawa, Kazuhiro; Moriya, Shota; Miyahara, Kana; Kazama, Hiromi; Hirota, Ayako; Takemura, Jun; Abe, Akihisa; Inazu, Masato; Hiramoto, Masaki; Tsukahara, Kiyoaki

    2016-01-01

    Autophagy, a self-digestive system for cytoplasmic components, is required to maintain the amino acid pool for cellular homeostasis. We previously reported that the macrolide antibiotics azithromycin (AZM) and clarithromycin (CAM) have an inhibitory effect on autophagy flux, and they potently enhance the cytocidal effect of various anticancer reagents in vitro. This suggests that macrolide antibiotics can be used as an adjuvant for cancer chemotherapy. Since cancer cells require a larger metabolic demand than normal cells because of their exuberant growth, upregulated autophagy in tumor cells has now become the target for cancer therapy. In the present study, we examined whether macrolides exhibit cytotoxic effect under an amino acid-starving condition in head and neck squamous cancer cell lines such as CAL 27 and Detroit 562 as models of solid tumors with an upregulated autophagy in the central region owing to hypovascularity. AZM and CAM induced cell death under the amino acid-depleted (AAD) culture condition in these cell lines along with CHOP upregulation, although they showed no cytotoxicity under the complete culture medium. CHOP knockdown by siRNA in the CAL 27 cells significantly suppressed macrolide-induced cell death under the AAD culture condition. CHOP-/- murine embryonic fibroblast (MEF) cell lines also attenuated AZM-induced cell death compared with CHOP+/+ MEF cell lines. Using a tet-off atg5 MEF cell line, knockout of atg5, an essential gene for autophagy, also induced cell death and CHOP in the AAD culture medium but not in the complete culture medium. This suggest that macrolide-induced cell death via CHOP induction is dependent on autophagy inhibition. The cytotoxicity of macrolide with CHOP induction was completely cancelled by the addition of amino acids in the culture medium, indicating that the cytotoxicity is due to the insufficient amino acid pool. These data suggest the possibility of using macrolides for “tumor-starving therapy”. PMID

  5. Vaccinia virus outperforms a panel of other poxviruses as a potent oncolytic agent for the control of head and neck squamous cell carcinoma cell lines.

    Science.gov (United States)

    Nichols, Anthony C; Yoo, John; Um, Sung; Mundi, Neil; Palma, David A; Fung, Kevin; Macneil, S Danielle; Koropatnick, James; Mymryk, Joe S; Barrett, John W

    2014-01-01

    Head and neck squamous cell carcinoma (HNSCC) is the fifth most common cancer worldwide. Existing therapies for advanced tumors have high failure rates and can have severe consequences in terms of pain, disfigurement, and poor speech and swallowing function. New treatment strategies are needed to improve outcomes for patients suffering with this disease and oncolytic viruses represent a promising approach. We infected six well-characterized HNSCC cell lines (Cal27, Detroit562, FaDu, SCC4, SCC15, SCC25), with increasing doses of a panel of poxviruses (including myxoma, vaccinia, raccoonpox and tanapox viruses) modified to express green fluorescence protein to determine which virus was the most effective oncolytic agent in cell-based assays. While myxoma, raccoonpox and tanapox displayed differing efficacy in the panel of cell lines, vaccinia virus was the most potent of the tested poxviruses and was highly effective in controlling cell growth in all cell lines. Oncolytic poxviruses, particularly vaccinia virus, were effective in killing HNSCC in vitro and hold promise as potential treatments for patients with HNSCC. Copyright © 2013 S. Karger AG, Basel.

  6. Drain Back, Low Flow Solar Combi Systems

    DEFF Research Database (Denmark)

    Perers, Bengt; Furbo, Simon; Fan, Jianhua

    2014-01-01

    Drain Back systems with ETC collectors are tested and analyzed in a Danish - Chinese cooperation project. Experiences from early work at DTU, with drain back, low flow systems, was used to design two systems: 1) One laboratory system at DTU and 2) One demonstration system in a single family house...... and that the performance can be enhanced. A combination of the drain back- and system expansion vessel was tested successfully. Small initial problems with installation and proposals for design improvements to avoid these in practice are described in the paper. Installer education and training is an important step to have...... success with drain back systems....

  7. Susceptibility to cytotoxic T cell lysis of cancer stem cells derived from cervical and head and neck tumor cell lines.

    Science.gov (United States)

    Liao, Tian; Kaufmann, Andreas M; Qian, Xu; Sangvatanakul, Voramon; Chen, Chao; Kube, Tina; Zhang, Guoyou; Albers, Andreas E

    2013-01-01

    To explore cancer stem cell susceptibility to a host's cytotoxic T lymphocyte (CTL)-mediated immune response. We compared the susceptibility of putative CSC generated from cancer cell lines to immunologic recognition and killing by alloantigen-specific CD8(+) CTL. CSC-enriched spheroid culture-derived cells (SDC) exhibited higher expression of ALDH, ICAM1 and of stem/progenitor cell markers on all 3 tumor cell lines investigated and lower MHC class I on the cervical cancer cell line as compared to their monolayer-derived cells (MDC). The expression of ICAM1 and MHCI was upregulated by IFN-γ treatment. CSC populations were less sensitive to MHC class I-restricted alloantigen-specific CD8(+) CTL lysis as compared to matched MDC. IFN-γ pretreatment resulted in over-proportionally enhanced lysis of SDC. Finally, the subset of ALDH(high) expressing SDC presented more sensitivity toward CD8(+) CTL killing than the ALDH(low) SDC. Tumor therapy resistance has been attributed to cancer stem cells (CSC). We show in vitro susceptibility of CSC to CTL-mediated lysis. Immunotherapy targeting of ALDH(+) CSC may therefore be a promising approach. Our results and method may be helpful for the development and optimization of adjuvants, as here exemplified for INF-γ, for CSC-targeted vaccines, independent of the availability of CSC-specific antigens.

  8. A gamma-ray telescope for on-line measurements of low boron concentrations in a head-phantom for BNCT

    Energy Technology Data Exchange (ETDEWEB)

    Verbakel, W.F.A.R.

    1996-06-01

    In Boron Neutron Capture Therapy the {sup 10}B(n, {alpha}){sup 7}Li reaction is used to create a tumour destructing field by the emitted high-LET (Linear Energy Transfer) particles. This reaction is accompanied by the emission of a photon of energy 478 keV. This can serve as a probe for detection of the reaction rate and thereby provide a tool to assess the boron concentration during therapy. An experimental configuration has been designed for on-line measurements of the {sup 10}B prompt gamma rays in a background of hydrogen neutron capture prompt gamma rays, neutrons and gamma rays coming from the reactor. At a facility with epithermal neutrons of the Low Flux Reactor a head phantom has been irradiated with neutorns. This phantom is filled with water and a small volume of 7.8 cm{sup 3} containing 62 ppm {sup 10}B, simulating a tumour. The experimental configuration for prompt gamma measurements has been expanded to perform tomography. The reconstruction of the position and the size of the tumour and its boron cencentration appeared to be possible. The first experiments at the therapy room in the High Flux Reactor showed that this method can probably be expanded for on-line monitoring of the total boron amount in a patients head. Next to this, Monte Carlo calculations and foil activation measurements have been performed to obtain the neutron spectrum of the epithermal beam of the LFR. With the insight achieved with these calculations it has been possible to optimize the total neutron flux. By introduction of a graphite scatter in the beam tube close to the reactr core, the flux has been rainsed with about 65%. With the computer code DORT neutron distributions over the phantom have been calculated for 47 energy groups. These calculations are necessary for ultimate boron tomography. (orig.).

  9. Alpha-2 Heremans Schmid Glycoprotein (AHSG) modulates signaling pathways in head and neck squamous cell carcinoma cell line SQ20B.

    Science.gov (United States)

    Thompson, Pamela D; Sakwe, Amos; Koumangoye, Rainelli; Yarbrough, Wendell G; Ochieng, Josiah; Marshall, Dana R

    2014-02-15

    This study was performed to identify the potential role of Alpha-2 Heremans Schmid Glycoprotein (AHSG) in Head and Neck Squamous Cell Carcinoma (HNSCC) tumorigenesis using an HNSCC cell line model. HNSCC cell lines are unique among cancer cell lines, in that they produce endogenous AHSG and do not rely, solely, on AHSG derived from serum. To produce our model, we performed a stable transfection to down-regulate AHSG in the HNSCC cell line SQ20B, resulting in three SQ20B sublines, AH50 with 50% AHSG production, AH20 with 20% AHSG production and EV which is the empty vector control expressing wild-type levels of AHSG. Utilizing these sublines, we examined the effect of AHSG depletion on cellular adhesion, proliferation, migration and invasion in a serum-free environment. We demonstrated that sublines EV and AH50 adhered to plastic and laminin significantly faster than the AH20 cell line, supporting the previously reported role of exogenous AHSG in cell adhesion. As for proliferative potential, EV had the greatest amount of proliferation with AH50 proliferation significantly diminished. AH20 cells did not proliferate at all. Depletion of AHSG also diminished cellular migration and invasion. TGF-β was examined to determine whether levels of the TGF-β binding AHSG influenced the effect of TGF-β on cell signaling and proliferation. Whereas higher levels of AHSG blunted TGF-β influenced SMAD and ERK signaling, it did not clearly affect proliferation, suggesting that AHSG influences on adhesion, proliferation, invasion and migration are primarily due to its role in adhesion and cell spreading. The previously reported role of AHSG in potentiating metastasis via protecting MMP-9 from autolysis was also supported in this cell line based model system of endogenous AHSG production in HNSCC. Together, these data show that endogenously produced AHSG in an HNSCC cell line, promotes in vitro cellular properties identified as having a role in tumorigenesis. © 2013 The Authors

  10. To drain or not to drain after thyroid surgery: A randomized ...

    African Journals Online (AJOL)

    Introduction: In many facilities, drains are routinely inserted after thyroidectomy with the aim of preventing hematoma formation and accumulation of seroma. The continued use of drains may be based more on tradition rather than proven scientific evidence. Objective: To assess the benefit of drain use after thyroidectomy by ...

  11. Numerical Study on Draining from Cylindrical Tank Using Stepped Drain Port

    Energy Technology Data Exchange (ETDEWEB)

    Son, Jong Hyeon; Park, Il Seouk [Kyungpook National University, Daegu (Korea, Republic of)

    2014-12-15

    An air-core vortex is generated during draining after stirring a rotating cylindrical tank or after filling it with water. The formation of the air-core vortex and the time of its formation are dependent on drain conditions such as the dimensions of the tank, the initial rotation or stirring speed, and the shape of the drain port. In this study, a draining process using a two-stage drain port was numerically investigated. The length and radius of the first drain stage located in the lower part of the drain port were kept constant, whereas the radius of the second drain stage was varied for simulating the draining process. The simulation was conducted by considering an axisymmetric swirling flow for all cases. The declining water level was monitored by an interface capturing method. Further, the effects of the radius of the second drain stage on the time of formation of the air-core vortex and the internal flow structure were investigated.

  12. Media filter drain : modified design evaluation.

    Science.gov (United States)

    2014-09-01

    The media filter drain (MFD), a stormwater water quality treatment best management practice, consists of media made up of : aggregate, perlite, gypsum and dolomite in a trench located along roadway shoulders with gravel and vegetative pre-filtering f...

  13. A CD44high/EGFRlow subpopulation within head and neck cancer cell lines shows an epithelial-mesenchymal transition phenotype and resistance to treatment.

    Directory of Open Access Journals (Sweden)

    Linnea La Fleur

    Full Text Available Mortality in head and neck squamous cell carcinoma (HNSCC is high due to emergence of therapy resistance which results in local and regional recurrences that may have their origin in resistant cancer stem cells (CSCs or cells with an epithelial-mesenchymal transition (EMT phenotype. In the present study, we investigate the possibility of using the cell surface expression of CD44 and epidermal growth factor receptor (EGFR, both of which have been used as stem cell markers, to identify subpopulations within HNSCC cell lines that differ with respect to phenotype and treatment sensitivity. Three subpopulations, consisting of CD44(high/EGFR(low, CD44(high/EGFR(high and CD44(low cells, respectively, were collected by fluorescence-activated cell sorting. The CD44(high/EGFR(low population showed a spindle-shaped EMT-like morphology, while the CD44(low population was dominated by cobblestone-shaped cells. The CD44(high/EGFR(low population was enriched with cells in G0/G1 and showed a relatively low proliferation rate and a high plating efficiency. Using a real time PCR array, 27 genes, of which 14 were related to an EMT phenotype and two with stemness, were found to be differentially expressed in CD44(high/EGFR(low cells in comparison to CD44(low cells. Moreover, CD44(high/EGFR(low cells showed a low sensitivity to radiation, cisplatin, cetuximab and gefitinib, and a high sensitivity to dasatinib relative to its CD44(high/EGFR(high and CD44(low counterparts. In conclusion, our results show that the combination of CD44 (high and EGFR (low cell surface expression can be used to identify a treatment resistant subpopulation with an EMT phenotype in HNSCC cell lines.

  14. Cost-effectiveness of adding cetuximab to platinum-based chemotherapy for first-line treatment of recurrent or metastatic head and neck cancer.

    Directory of Open Access Journals (Sweden)

    Malek B Hannouf

    Full Text Available PURPOSE: To assess the cost effectiveness of adding cetuximab to platinum-based chemotherapy in first-line treatment of patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC from the perspective of the Canadian public healthcare system. METHODS: We developed a Markov state transition model to project the lifetime clinical and economic consequences of recurrent or metastatic HNSCC. Transition probabilities were derived from a phase III trial of cetuximab in patients with recurrent or metastatic HNSCC. Cost estimates were obtained from London Health Sciences Centre and the Ontario Case Costing Initiative, and expressed in 2011 CAD. A three year time horizon was used. Future costs and health benefits were discounted at 5%. RESULTS: In the base case, cetuximab plus platinum-based chemotherapy compared to platinum-based chemotherapy alone led to an increase of 0.093 QALY and an increase in cost of $36,000 per person, resulting in an incremental cost effectiveness ratio (ICER of $386,000 per QALY gained. The cost effectiveness ratio was most sensitive to the cost per mg of cetuximab and the absolute risk of progression among patients receiving cetuximab. CONCLUSION: The addition of cetuximab to standard platinum-based chemotherapy in first-line treatment of patients with recurrent or metastatic HNSCC has an ICER that exceeds $100,000 per QALY gained. Cetuximab can only be economically attractive in this patient population if the cost of cetuximab is substantially reduced or if future research can identify predictive markers to select patients most likely to benefit from the addition of cetuximab to chemotherapy.

  15. Effects of full-stream carbon filtration on the development of head and lateral line erosion syndrome (HLLES) in ocean surgeon.

    Science.gov (United States)

    Stamper, M Andrew; Kittell, Michele M; Patel, Erin E; Corwin, Allison L

    2011-09-01

    Head and lateral line erosion syndrome (HLLES) is a common but very poorly understood disease of marine aquarium fish. One suspected etiology is the use of granulated activated carbon (GAC) to filter the water. Seventy-two ocean surgeons Acanthurus bahianus were distributed among three carbon-negative control systems and three GAC-treated systems such that each tank contained approximately the same total body mass. Each replicate system was made up of two 250-L circular tanks with a common filtration system (6 fish per tank, 12 fish per replicate system). The GAC-treated tanks were exposed to full-stream, extruded coconut shell activated carbon, which produced a mean total organic carbon content of 0.4 mg/L. The results of this study indicate that extruded coconut shell activated carbon filtering at full-stream rates can cause HLLES-type lesions in ocean surgeons. The HLLES developed exponentially over 15 d, beginning in the chin region. This was followed by pitting in the cheek region, which expanded until erosions coalesced. Once the carbon was discontinued, the processes reversed in a mean time of 49 d. As the lesions healed, they reverted from the coalesced to the pitted stage and then darkened before returning to normal.

  16. Laparoscopic radical prostatectomy: omitting a pelvic drain

    Directory of Open Access Journals (Sweden)

    David Canes

    2008-03-01

    Full Text Available PURPOSE: Our goal was to assess outcomes of a selective drain placement strategy during laparoscopic radical prostatectomy (LRP with a running urethrovesical anastomosis (RUVA using cystographic imaging in all patients. Materials and Methods: A retrospective chart review was performed for all patients undergoing LRP between January 2003 and December 2004. The anastomosis was performed using a modified van Velthoven technique. A drain was placed at the discretion of the senior surgeon when a urinary leak was demonstrated with bladder irrigation, clinical suspicion for a urinary leak was high, or a complex bladder neck reconstruction was performed. Routine postoperative cystograms were obtained. RESULTS: 208 patients underwent LRP with a RUVA. Data including cystogram was available for 206 patients. The overall rate of cystographic urine leak was 5.8%. A drain was placed in 51 patients. Of these, 8 (15.6% had a postoperative leak on cystogram. Of the 157 undrained patients, urine leak was radiographically visible in 4 (2.5%. The higher leak rate in the drained vs. undrained cohort was statistically significant (p = 0.002. Twenty-four patients underwent pelvic lymph node dissection (8 drained, 16 undrained. Three undrained patients developed lymphoceles, which presented clinically on average 3 weeks postoperatively. There were no urinomas or hematomas in either group. CONCLUSIONS: Routine placement of a pelvic drain after LRP with a RUVA is not necessary, unless the anastomotic integrity is suboptimal intraoperatively. Experienced clinical judgment is essential and accurate in identifying patients at risk for postoperative leakage. When suspicion is low, omitting a drain does not increase morbidity.

  17. 21 CFR 868.5995 - Tee drain (water trap).

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Tee drain (water trap). 868.5995 Section 868.5995...) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5995 Tee drain (water trap). (a) Identification. A tee drain (water trap) is a device intended to trap and drain water that collects in ventilator...

  18. Identification of human papillomavirus (HPV) 16 DNA integration and the ensuing patterns of methylation in HPV-associated head and neck squamous cell carcinoma cell lines.

    Science.gov (United States)

    Hatano, Takashi; Sano, Daisuke; Takahashi, Hideaki; Hyakusoku, Hiroshi; Isono, Yasuhiro; Shimada, Shoko; Sawakuma, Kae; Takada, Kentaro; Oikawa, Ritsuko; Watanabe, Yoshiyuki; Yamamoto, Hiroyuki; Itoh, Fumio; Myers, Jeffrey N; Oridate, Nobuhiko

    2017-04-01

    Recent studies showed that human papillomavirus (HPV) integration contributes to the genomic instability seen in HPV-associated head and neck squamous cell carcinoma (HPV-HNSCC). However, the epigenetic alterations induced after HPV integration remains unclear. To identify the molecular details of HPV16 DNA integration and the ensuing patterns of methylation in HNSCC, we performed next-generation sequencing using a target-enrichment method for the effective identification of HPV16 integration breakpoints as well as the characterization of genomic sequences adjacent to HPV16 integration breakpoints with three HPV16-related HNSCC cell lines. The DNA methylation levels of the integrated HPV16 genome and that of the adjacent human genome were also analyzed by bisulfite pyrosequencing. We found various integration loci, including novel integration sites. Integration loci were located predominantly in the intergenic region, with a significant enrichment of the microhomologous sequences between the human and HPV16 genomes at the integration breakpoints. Furthermore, various levels of methylation within both the human genome and the integrated HPV genome at the integration breakpoints in each integrant were observed. Allele-specific methylation analysis suggested that the HPV16 integrants remained hypomethylated when the flanking host genome was hypomethylated. After integration into highly methylated human genome regions, however, the HPV16 DNA became methylated. In conclusion, we found novel integration sites and methylation patterns in HPV-HNSCC using our unique method. These findings may provide insights into understanding of viral integration mechanism and virus-associated carcinogenesis of HPV-HNSCC. © 2016 UICC.

  19. FROM BRAIN DRAIN TO BRAIN NETWORKING

    Directory of Open Access Journals (Sweden)

    Irina BONCEA

    2015-06-01

    Full Text Available Scientific networking is the most accessible way a country can turn the brain drain into brain gain. Diaspora’s members offer valuable information, advice or financial support from the destination country, without being necessary to return. This article aims to investigate Romania’s potential of turning brain drain into brain networking, using evidence from the medical sector. The main factors influencing the collaboration with the country of origin are investigated. The conclusions suggest that Romania could benefit from the diaspora option, through an active implication at institutional level and the implementation of a strategy in this area.

  20. Reverse draining of a magnetic soap film.

    Science.gov (United States)

    Moulton, D E; Pelesko, J A

    2010-04-01

    We investigate the draining of a vertical magnetic soap film in the presence of a strong, nonuniform magnetic field. A colloidal suspension of magnetic nanoparticles in a regular soap solution yields a magnetic soap solution, from which a soap film is formed across an isolated frame. Experiments demonstrate that with a strong magnet placed above the frame, the film may be made to flow upward against gravity. The amount of film draining upward is altered by varying the distance between the frame and magnet. A first mathematical model is developed for the evolution of the film. Simulations demonstrate qualitative agreement with the experiment.

  1. Increased radiosensitivity of HPV-positive head and neck cancer cell lines due to cell cycle dysregulation and induction of apoptosis

    Energy Technology Data Exchange (ETDEWEB)

    Arenz, Andrea; Ziemann, Frank; Wittig, Andrea; Preising, Stefanie; Engenhart-Cabillic, Rita [Philipps-University, Department of Radiotherapy and Radiooncology, BMFZ - Biomedical Research Center, Marburg (Germany); Mayer, Christina; Wagner, Steffen; Klussmann, Jens-Peter; Wittekindt, Claus [Justus Liebig University, Department of Otorhinolaryngology and Head and Neck Surgery, Giessen (Germany); Dreffke, Kirstin [Philipps-University, Institute for Radiobiology and Molecular Radiooncology, Marburg (Germany)

    2014-09-15

    Human Papillomavirus (HPV)-related head and neck squamous cell carcinoma (HNSCC) respond favourably to radiotherapy as compared to HPV-unrelated HNSCC. We investigated DNA damage response in HPV-positive and HPV-negative HNSCC cell lines aiming to identify mechanisms, which illustrate reasons for the increased sensitivity of HPV-positive cancers of the oropharynx. Radiation response including clonogenic survival, apoptosis, DNA double-strand break (DSB) repair, and cell cycle redistribution in four HPV-positive (UM-SCC-47, UM-SCC-104, 93-VU-147T, UPCI:SCC152) and four HPV-negative (UD-SCC-1, UM-SCC-6, UM-SCC-11b, UT-SCC-33) cell lines was evaluated. HPV-positive cells were more radiosensitive (mean SF2: 0.198 range: 0.22-0.18) than HPV-negative cells (mean SF2: 0.34, range: 0.45-0.27; p = 0.010). Irradiated HPV-positive cell lines progressed faster through S-phase showing a more distinct accumulation in G2/M. The abnormal cell cycle checkpoint activation was accompanied by a more pronounced increase of cell death after x-irradiation and a higher number of residual and unreleased DSBs. The enhanced responsiveness of HPV-related HNSCC to radiotherapy might be caused by a higher cellular radiosensitivity due to cell cycle dysregulation and impaired DNA DSB repair. (orig.) [German] Fuer Patienten mit HPV-assoziierten Kopf-Hals-Tumoren (HNSCC) ist im Vergleich zu Patienten mit nicht-HPV-assoziierten Tumoren ein besseres Ueberleben nach Radiotherapie gesichert. Ziel der Untersuchung war die Identifizierung von Unterschieden in der zellulaeren DNA-Schadensantwort von HPV-positiven und HPV-negativen Zelllinien, wodurch die bereits in Erprobung stehende Deeskalation einer Radiotherapie bei Patienten mit HPV-assoziierten HNSCC durch experimentelle Daten abgesichert werden koennte. Klonogenes Ueberleben, Induktion von Apoptose, DNA-Doppelstrang-Reparatur und Zellzyklusverhalten wurden in vier HPV-positiven (UM-SCC-47, UM-SCC-104, 93-VU-147T, UPCI:SCC152) und vier HPV

  2. From Brain Drain to Brain Circulation

    African Journals Online (AJOL)

    Ademu

    problematic for developing nations, where it is widespread. In these countries, higher education and professional certification are often viewed as the surest path to escape from a troubled economy or difficult political situation. Brain drain can be described as “soft brain drain” which is the non-availability of research results ...

  3. The European Politics of Brain Drain

    DEFF Research Database (Denmark)

    Hasselbalch, Jacob

    on the issue. Although the current balance is weighted in favor of a supply-side, employability logic towards brain drain, there is evidence of a schism within the Commission that presents an opportunity to productively engage with other understandings of the issue in pursuit of best practices....

  4. Chronic Cutaneous Draining Sinus of Dental Origin

    African Journals Online (AJOL)

    surgery. It can also result from infection or inflammation. The root canal of a necrotic tooth is a source of predominantly anaerobic microbes. The tooth may present without any symptoms, except a cutaneous draining sinus.[1] Due to the extra-oral location of the sinus, patients tend to seek medical care first. These cutaneous.

  5. Studies on groundwater recharge through surface drains

    African Journals Online (AJOL)

    2005-04-02

    Apr 2, 2005 ... to change in the value of specific yield than hydraulic conductivity. Keywords: finite difference model, groundwater recharge, surface drain, water table. List of symbols a. = area of cross-section of flow at any z ..... avg. wt = Q(t)/(2L*drl). (23). Figure 2. Flow chart of the groundwater recharge model for surface.

  6. The safe use of spinal drains in thoracic aortic surgery.

    Science.gov (United States)

    Field, Mark; Doolan, Jim; Safar, Maria; Kuduvalli, Manoj; Oo, Aung; Mills, Keith; Kendall, Jonathan; Desmond, Michael

    2011-12-01

    Paraplegia is a devastating complication which may occur following surgery on the thoracic aorta. The use of a cerebrospinal fluid drain (CSFD) has helped reduce the incidence of neurological deficit; however, the management of patients with a CSFD postsurgery requires nurses and doctors to have expertise and awareness of the associated complications. The National Patient Safety Agency (UK) has highlighted a number of cases involving inadvertent spinal injections throughout the UK National Health Service (NHS). To this end we have introduced a protocol or 'care bundle' for safe CSFD care as well as drain management. The protocol was developed by medical and nursing staff at our institution based on clinical experience and literature reviews over a two-year period (2008-2010). Interventions undertaken during the development of the protocol included discussion with the UK National Patient Safety Agency (NPSA). Content of the protocol was reviewed by internal regulatory bodies within the hospital prior to ratification and general dissemination. Clear guidance is given within the policy on the standards expected when caring for the line and managing drainage according to agreed parameters of spinal cord perfusion pressure. The protocol constitutes five documents which guide staff in the care of CSFD, its routine management, documentation and interventions necessary once neurological deficit is detected. Document 1 which is a checklist, communication tool and aide-memoire was developed to ensure effective management, when the patient arrives in intensive care unit (ICU) from theatre. Document 2 ensures that early detection of a neurological deficit is noted and with Document 3 is acted upon immediately to reverse the injury. Document 4 provides information on the safe administration of analgesia via the spinal drain and has reference to the Glasgow Coma Scale. Document 5 is a bespoke observation chart for documenting CSFD pressure and cerebrospinal fluid drainage. In

  7. Perfect drain for the Maxwell Fish Eye lens.

    OpenAIRE

    Gonzalez Lopez, Juan Carlos; Benitez Gimenez, Pablo; Miñano Dominguez, Juan Carlos

    2011-01-01

    Perfect imaging of electromagnetic waves using the Maxwell fish eye (MFE) requires a new concept: a point called the perfect drain that we shall call the perfect point drain. From the mathematical point of view, a perfect point drain is just like an ideal point source, except that it drains power from the electromagnetic field instead of generating it. We introduce here the perfect drain for the MFE as a dissipative region of non-zero size that completely drains the power from the point source....

  8. Drain Current Modulation of a Single Drain MOSFET by Lorentz Force for Magnetic Sensing Application.

    Science.gov (United States)

    Chatterjee, Prasenjit; Chow, Hwang-Cherng; Feng, Wu-Shiung

    2016-08-30

    This paper reports a detailed analysis of the drain current modulation of a single-drain normal-gate n channel metal-oxide semiconductor field effect transistor (n-MOSFET) under an on-chip magnetic field. A single-drain n-MOSFET has been fabricated and placed in the center of a square-shaped metal loop which generates the on-chip magnetic field. The proposed device designed is much smaller in size with respect to the metal loop, which ensures that the generated magnetic field is approximately uniform. The change of drain current and change of bulk current per micron device width has been measured. The result shows that the difference drain current is about 145 µA for the maximum applied magnetic field. Such changes occur from the applied Lorentz force to push out the carriers from the channel. Based on the drain current difference, the change in effective mobility has been detected up to 4.227%. Furthermore, a detailed investigation reveals that the device behavior is quite different in subthreshold and saturation region. A change of 50.24 µA bulk current has also been measured. Finally, the device has been verified for use as a magnetic sensor with sensitivity 4.084% (29.6 T(-1)), which is very effective as compared to other previously reported works for a single device.

  9. Carbon accumulation in pristine and drained mires

    Energy Technology Data Exchange (ETDEWEB)

    Maekilae, M.

    2011-07-01

    The carbon accumulation of 73 peat columns from 48 pristine and drained mires was investigated using a total of 367 dates and age-depth models derived from bulk density measurements. Peat columns were collected from mires of varying depth, age, degree of natural state and nutrient conditions in aapa mire and raised bog regions and coastal mires from southern and central Finland and Russian Karelia. Particular attention was paid to the accumulation of carbon over the last 300 years, as this period encompasses the best estimates of the oxic layer (acrotelm) age across the range of sites investigated. In general, drained mires are initially more nutrient-rich than pristine mires. Organic matter decomposes more rapidly at drained sites than at pristine sites, resulting in thinner peat layers and carbon accumulation but a higher dry bulk density and carbon content. The average carbon accumulation was calculated as 24.0 g m-2 yr-1 at pristine sites and 19.4 g m-2 yr-1 at drained sites, while for peat layers younger than 300 years the respective figures were 45.3 and 34.5 g m-2 yr-1 at pristine and drained sites. For the <300-year-old peat layers studied here, the average thickness was 19 cm less and the carbon accumulation rate 10.8 g m-2 yr-1 lower in drained areas than in pristine areas. The amount carbon accumulation of surface peat layers depends upon the mire site type, vegetation and natural state; variations reflect differences in plant communities as well as factors that affect biomass production and decay rates. The highest accumulation rates and thus carbon binding for layers younger than 300 years were measured in the ombrotrophic mire site types (Sphagnum fuscum bog and Sphagnum fuscum pine bog), and the second highest rates in wet, treeless oligotrophic and minerotrophic mire site types. The lowest values of carbon accumulation over the last 300 years were obtained for the most transformed, sparsely forested and forested mire site types, where the water

  10. Climate mitigation scenarios of drained peat soils

    Science.gov (United States)

    Kasimir Klemedtsson, Åsa; Coria, Jessica; He, Hongxing; Liu, Xiangping; Nordén, Anna

    2014-05-01

    The national inventory reports (NIR) submitted to the UNFCCC show Sweden - which as many other countries has wetlands where parts have been drained for agriculture and forestry purposes, - to annually emit 12 million tonnes carbon dioxide equivalents, which is more GHG'es than industrial energy use release in Sweden. Similar conditions can be found in other northern countries, having cool and wet conditions, naturally promoting peat accumulation, and where land use management over the last centuries have promoted draining activities. These drained peatland, though covering only 2% of the land area, have emissions corresponding to 20% of the total reported NIR emissions. This substantial emission contribution, however, is hidden within the Land Use Land Use Change and Forestry sector (LULUCF) where the forest Carbon uptake is even larger, which causes the peat soil emissions become invisible. The only drained soil emission accounted in the Swedish Kyoto reporting is the N2O emission from agricultural drained organic soils of the size 0.5 million tonnes CO2e yr-1. This lack of visibility has made incentives for land use change and management neither implemented nor suggested, however with large potential. Rewetting has the potential to decrease soil mineralization, why CO2 and N2O emissions are mitigated. However if the soil becomes very wet CH4 emission will increase together with hampered plant growth. By ecological modeling, using the CoupModel the climate change mitigation potential have been estimated for four different land use scenarios; 1, Drained peat soil with Spruce (business as usual scenario), 2, raised ground water level to 20 cm depth and Willow plantation, 3, raised ground water level to 10 cm depth and Reed Canary Grass, and 4, rewetting to an average water level in the soil surface with recolonizing wetland plants and mosses. We calculate the volume of biomass production per year, peat decomposition, N2O emission together with nitrate and DOC

  11. Using MODFLOW drains to simulate groundwater flow in a karst environment

    Energy Technology Data Exchange (ETDEWEB)

    Quinn, J.; Tomasko, D.; Glennon, M.A.; Miller, S.F.; McGinnis, L.D.

    1998-07-01

    Modeling groundwater flow in a karst environment is both numerically challenging and highly uncertain because of potentially complex flowpaths and a lack of site-specific information. This study presents the results of MODFLOW numerical modeling in which drain cells in a finite-difference model are used as analogs for preferential flowpaths or conduits in karst environments. In this study, conduits in mixed-flow systems are simulated by assigning connected pathways of drain cells from the locations of tracer releases, sinkholes, or other karst features to outlet springs along inferred flowpaths. These paths are determined by the locations of losing stream segments, ephemeral stream beds, geophysical surveys, fracture lineaments, or other surficial characteristics, combined with the results of dye traces. The elevations of the drains at the discharge ends of the inferred flowpaths are estimated from field data and are adjusted when necessary during model calibration. To simulate flow in a free-flowing conduit, a high conductance is assigned to each drain to eliminate the need for drain-specific information that would be very difficult to obtain. Calculations were performed for a site near Hohenfels, Germany. The potentiometric surface produced by the simulations agreed well with field data. The head contours in the vicinity of the karst features behaved in a manner consistent with a flow system having both diffuse and conduit components, and the sum of the volumetric flow out of the drain cells agreed closely with spring discharges and stream flows. Because of the success of this approach, it is recommended for regional studies in which little site-specific information (e.g., location, number, size, and conductivity of fractures and conduits) is available, and general flow characteristics are desired.

  12. Drained Triaxial Tests on Eastern Scheldt Sand

    DEFF Research Database (Denmark)

    Praastrup, U.; Jakobsen, Kim Parsberg

    In the process of understanding and developing models for geomaterials, the stress-strain behaviour is commonly studied by performing triaxial tests. In the present study static triaxial tests have been performed to gain knowledge of the stress-strain behaviour of frictional materials during mono...... monotonic loading. The tests reported herein are all drained tests, starting from different initial states of stress and following various stress paths. AIl the tests are performed on reconstituted medium dense specimens of Eastern Scheldt Sand....

  13. Gender bias and the female brain drain

    OpenAIRE

    Aniruddha Mitra; James T. Bang

    2010-01-01

    This paper contributes to the emerging literature on gender differences in the causes and consequences of brain drain. Differentiating between gender bias in the access to economic opportunities and gender differentials in economic outcomes, we find that differences in access have a significant impact on the emigration of highly-skilled women relative to that of men. However, differentials in outcomes do not have a significant impact. Additionally, the structure of political institutions in t...

  14. Subarachnoid hemorrhage due to retained lumbar drain.

    Science.gov (United States)

    Guppy, Kern H; Silverthorn, James W; Akins, Paul T

    2011-12-01

    Intrathecal spinal catheters (lumbar drains) are indicated for several medical and surgical conditions. In neurosurgical procedures, they are used to reduce intracranial and intrathecal pressures by diverting CSF. They have also been placed for therapeutic access to administer drugs, and more recently, vascular surgeons have used them to improve spinal cord perfusion during the treatment of thoracic aortic aneurysms. Insertion of these lumbar drains is not without attendant complications. One complication is the shearing of the distal end of the catheter with a resultant retained fragment. The authors report the case of a 65-year-old man who presented with a subarachnoid hemorrhage due to the migration of a retained lumbar drain that sheared off during its removal. To the best of the authors' knowledge, this is the first case of rostral migration of a retained intrathecal catheter causing subarachnoid hemorrhage. The authors review the literature on retained intrathecal spinal catheters, and their findings support either early removal of easily accessible catheters or close monitoring with serial imaging.

  15. Brain drain: Propulsive factors and consequences

    Directory of Open Access Journals (Sweden)

    Dragan ILIC

    2018-01-01

    Full Text Available When speaking about the total number of highly educated individuals’ migration, it is easy to spot that it is rapidly increasing. The brain drain issues should be taken very seriously especially in under developed and in the developing countries, knowing that the human capital is globally mobile and that highly educated individuals can without any issues market their knowledge around the globe. Dealing with it requires a carefully tailored strategy for these countries, which are suffering from severe human capital losses on annual basis. Since the labor markets of today are highly competitive, it is necessary for these countries to secure good advancement and doing business opportunities. The purpose of this research is to provide an insight into the key propulsive factors and potential consequences caused by the brain drain. The method used in order to conduct the research was a carefully designed questionnaire taken by the date subject enrolled at the third and fourth years of state governed and privately owned universities. This research shows that one of the key reasons for brain drain in underdeveloped and in the developing countries is shortage of further educational advancement opportunities.

  16. Retinoid metabolism and all-trans retinoic acid-induced growth inhibition in head and neck squamous cell carcinoma cell lines

    NARCIS (Netherlands)

    Braakhuis, B.J.M.; Klaassen, I.; Leede, B.M. van der; Cloos, J.; Brakenhoff, R.H.; Copper, M.P.; Teerlink, T.; Hendriks, H.F.J.; Saag, P.T. van der; Snow, G.B.

    1997-01-01

    Retinoids can reverse potentially premalignant lesions and prevent second primary tumours in patients with head and neck squamous cell carcinoma (HNSCC). Furthermore, it has been reported that acquired resistance to all-trans retinoic acid (RA) in leukaemia is associated with decreased plasma peak

  17. Design and construction of a French drain for groundwater diversion in solid waste storage area six at the Oak Ridge National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Davis, E.C.; Stansfield, R.G.

    1984-05-01

    Engineering modifiations or engineered barriers have been suggested as a possible means of improving the performance of low-level waste disposal sites located in the humid eastern United States. Design and construction of a passive French drain, located in Solid Waste Storage Area No. 6 at the Oak Ridge National Laboratory. The drain was designed to hydrologically isolate a 0.44-ha area that contains a group of 49 low-level waste trenches by separating it from upgradient groundwater recharge areas. The 252-m drain (maximum depth = 9 m) that surrounds the group of trenches on the north and east sides was excavated, lined with filter fabric, backfilled with crushed stone, and covered with a 0.6 m layer of excavated material at an estimated cost of $153,000. Of the 17 days it took to complete the work, about 5 days were spent excavating sidewall slide material that fell into the drain during excavation. Photography of the drain wall revealed the contorted structure of the weathered shale, which was responsible for many of the slides. Monitoring wells placed at intervals on the drain centerline indicate that groundwater is draining from the surrounding Maryville Formation (Conasauga Group); flows at catch basin No. 2 ranged from a base flow of 4 to 7 L/min to a maximum of 35 L/min, recorded on October 13. In response to groundwater flow in the drain, water levels in several monitoring wells adjacent to the drain have dropped by as much as 2.24 m to an elevation only slightly higher than the bottom of the French drain. In addition to the general lowering of the water table in the vicinity of the drain, water levels in three trenches began to subside, indicating that the drain is beginning to have an effect on the water in the trenches as well. Further monitoring of both drain discharge and water levels in monitoring wells across the site is continuing.

  18. MEDICAL BRAIN DRAIN - A THEORETICAL APPROACH

    Directory of Open Access Journals (Sweden)

    Boncea Irina

    2013-07-01

    Full Text Available Medical brain drain is defined as the migration of health personnel from developing countries to developed countries and between industrialized nations in search for better opportunities. This phenomenon became a global growing concern due to its impact on both the donor and the destination countries. This article aims to present the main theoretical contributions starting from 1950 until today and the historical evolution, in the attempt of correlating the particular case of medical brain drain with the theory and evolution of the brain drain in general. This article raises questions and offers answers, identifies the main issues and looks for possible solutions in order to reduce the emigration of medical doctors. Factors of influence include push (low level of income, poor working conditions, the absence of job openings and social recognition, oppressive political climate and pull (better remuneration and working conditions, prospects for career development, job satisfaction, security factors. Developing countries are confronting with the loss of their most valuable intellectuals and the investment in their education, at the benefit of developed nations. An ethical debate arises as the disparities between countries increases, industrialized nations filling in the gaps in health systems with professionals from countries already facing shortages. However, recent literature emphasizes the possibility of a “beneficial brain drain” through education incentives offered by the emigration prospects. Other sources of “brain gain” for donor country are the remittances, the scientific networks and return migration. Measures to stem the medical brain drain involve the common effort and collaboration between developing and developed countries and international organizations. Measures adopted by donor countries include higher salaries, better working conditions, security, career opportunities, incentives to stimulate return migration. Destination

  19. Effects of drain bias on the statistical variation of double-gate tunnel field-effect transistors

    Science.gov (United States)

    Choi, Woo Young

    2017-04-01

    The effects of drain bias on the statistical variation of double-gate (DG) tunnel field-effect transistors (TFETs) are discussed in comparison with DG metal-oxide-semiconductor FETs (MOSFETs). Statistical variation corresponds to the variation of threshold voltage (V th), subthreshold swing (SS), and drain-induced barrier thinning (DIBT). The unique statistical variation characteristics of DG TFETs and DG MOSFETs with the variation of drain bias are analyzed by using full three-dimensional technology computer-aided design (TCAD) simulation in terms of the three dominant variation sources: line-edge roughness (LER), random dopant fluctuation (RDF) and workfunction variation (WFV). It is observed than DG TFETs suffer from less severe statistical variation as drain voltage increases unlike DG MOSFETs.

  20. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... an IV line, into a vein in your hand or arm. A saline solution may be used ... Tumor Treatment Magnetic Resonance Imaging (MRI) Safety Alzheimer's Disease Head Injury Brain Tumors Images related to Magnetic ...

  1. Hydrological modelling of drained blanket peatland

    Science.gov (United States)

    Ballard, C. E.; McIntyre, N.; Wheater, H. S.; Holden, J.; Wallage, Z. E.

    2011-09-01

    SummaryOpen ditch drainage is a commonly implemented land management practice in upland blanket peatlands, particularly in the UK, where policy decisions between the 1940s and 1970s led to widespread drainage of the uplands. The change in the hydrological regime associated with the drainage of blanket peat is poorly understood, yet has perceived importance for flooding, low flows and water quality. We propose a new simplified physics-based model that allows the associated hydrological processes and flow responses to be explored. The model couples four one-dimensional models to represent a three-dimensional hillslope, allowing for the exploration of flow and water table response throughout the model domain for a range of drainage configurations and peat properties. The model is tested against a data set collected from Oughtershaw Beck, UK, with results showing good model performance for wet periods although less conformity with borehole observations during rewetting periods. A wider exploration of model behaviour indicates that the model is consistent with the hydrological response reported in the literature for a number of drained blanket peat sites, and therefore has potential to provide guidance to decision makers concerning the effects of management practices. Through a global sensitivity analysis, we conclude that further field investigations to assist in the surface and drain roughness parameterisation would help reduce the uncertainty in the model predictions.

  2. Variation in Drain Management After Pancreatoduodenectomy: Early Versus Delayed Removal.

    Science.gov (United States)

    Beane, Joal D; House, Michael G; Ceppa, Eugene P; Dolejs, Scott C; Pitt, Henry A

    2017-10-23

    The objectives are to report practice patterns and management of operatively placed drains and to compare outcomes in patients with early versus delayed drain removal after pancreatoduodenectomy. Early drain removal after pancreatoduodenectomy, when guided by postoperative day (POD) 1 drain fluid amylase (DFA-1), is associated with reduced rates of clinically relevant postoperative pancreatic fistula (CR-POPF). However, whether surgeons have altered their management based on this strategy is unknown. The American College of Surgeons-National Surgical Quality Improvement Program (ACS-NSQIP) 2014 Participant Use File was queried to identify patients having undergone pancreatoduodenectomy (n = 3093). Patients with intraoperatively placed drains were stratified according to measurement of DFA-1 and day of drain removal. Patients with POD 1 DFA-1 of ≤5000 U/L whose drains were removed by POD 3 were propensity score-matched with patients whose drains were removed after POD 3. Of 2698 patients, 580 (21.5%) had a DFA-1 recorded. Measurement of DFA-1 was associated with earlier time to drain removal and shorter postoperative length of stay (P DFA-1 was ≤5000 U/L was associated with significant (P < 0.05) reductions in overall morbidity (35.3% vs 52.3%), CR-POPF (0.9% vs 7.9%), and length of stay (6 vs 8 days). Significant variation exists in the use of drain fluid amylase in the management and timing of surgical drain removal after pancreatoduodenectomy. Clinical outcomes are best when drain fluid amylase is low and operatively placed drains are removed by POD 3.

  3. The effect of retinoic acid on radiosensitivity analyzed by linear-quadratic model and apoptosis in head and neck squamous carcinoma cell lines

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Eun Sook; Kang, Bum Hyun; Heo, Min Suk; Lee, Sam Sun; Choi, Hyun Bae; Choi, Soon Chul; Park, Tae Won [Seoul National Univ. College of Dentistry, Seoul (Korea, Republic of)

    2001-09-15

    To evaluate the effect of all-trans-retinoic acid on radiosensitivity and radiation-induced apoptosis in NHOK, HEp-2 and FaDu cell lines. We measured the changes in survival fraction at 2 Gy (SF2), {alpha} and {beta} after treatment of retinoic acid (1 {mu}M) prior to irradiation with doses of 2, 4, 6 and 10 Gy and correlated the radiosensitizing effect of retinoic acid with them. Also, apoptosis indention was assayed with the flow cytometry on days 1, 2, 3, 4 and 5 after irradiation (2, 10 and 20 Gy) combined with retinoic acid. SF2 values for NHOK, HEp-2 and FaDu cell lines were 0.54, 0.64 and 0.41, respectively and the cell line of FaDu was the most radiosensitive. For cell lines of NHOK and HEp-2, pretreatment of cells with retinoic acid resulted in a significant decrease of the SF2 values. The {alpha}/{beta} ratios of x-ray survival curve were 8.714 (NHOK), 4.098 (HEp-2) and 11.79 (FaDu). The {alpha}/{beta} radio for NHOK decreased on pretreatment with retinoic acid, whereas those for HEp-2 and FaDu increased. Radiation induced apoptosis in all cell lines but, retinoic acid did not affect the apoptosis.

  4. Groundwater Head Control of Catchment Nitrate Export

    Science.gov (United States)

    Musolff, A.; Schmidt, C.; Rode, M.; Fleckenstein, J. H.

    2014-12-01

    Elevated nutrient fluxes from agricultural catchments affect downstream water resources. A method to assess nutrient fluxes is the evaluation of the export regime. The export regime classifies the relation between concentration and discharge and integrates mobilization as well as retention processes. Solutes can be exported chemostatically (variance of concentration regimes of nitrate in a series of neighboring sub-catchments of the Central German River Bode catchment. We found an accretion pattern of nitrate with increasing concentration when discharge is increasing and thus a chemodynamic export regime. Here we follow a nested approach and have a closer look at the controls of nitrate export in the small (1.4 km2) headwater catchment of the Sauerbach stream. The Sauerbach catchment is dominated by agricultural land use and is characterized by tile drains. We hypothesize that discharge as well as nitrate export is controlled by the groundwater head variability over time. To that end we follow a joint data analysis of discharge, groundwater heads and nitrate concentrations in groundwater, tile drains and surface water. At the gauging station the nitrate export is chemodynamic exhibiting the typical accretion pattern also found at the larger scale. Our data analysis shows that nitrate export regime is in two ways controlled by the depth to groundwater and the groundwater head variability: Discharge increases with increasing groundwater heads due to the activation of tile drains. On the other hand, depth to groundwater and passage through the unsaturated zone is the major control of aquifer nitrate concentration. At wells with larger depth to groundwater nitrate concentrations are significantly lower than at more shallow wells indicating retention processes in the unsaturated zone. Therefore the concentration in the stream increases with increasing heads since the activated tiles drain shallow groundwater with higher nitrate concentrations. We can thus show that the

  5. Head Injuries

    Science.gov (United States)

    ... ATV) Safety Balance Disorders Knowing Your Child's Medical History First Aid: Falls First Aid: Head Injuries Preventing Children's Sports Injuries Getting Help: Know the Numbers Concussions Stay ...

  6. Drain Back Systems in Laboratory and in Practice

    DEFF Research Database (Denmark)

    Perers, Bengt; Furbo, Simon; Fan, Jianhua

    2015-01-01

    with less components and that the performance can be enhanced. Also problems with long term degradation of glycol collector loops are totally avoided. A combination of the drain back and system expansion vessel was tested successfully. It is very important to achieve a continuous slope for the pipes...... step to have success with drain back systems. Practices used in glycol systems may give serious failures. Key-words: Drain Back, Low Flow, Solar Combi System, ETC collectors....

  7. Numerical investigation of underground drain radius, depth and location on uplift pressure reduction (Case study: Tabriz diversion dam

    Directory of Open Access Journals (Sweden)

    Farzin Salmasi

    2016-06-01

    Full Text Available Water penetration from beneath of built structures on permeable soils causes uplift force along the contact of structure with foundation. This uplift force reduces hydraulic structure stability. Typically, these instabilities occur due to under-pressure development (uplift force, gradual inner degradation of foundation material (piping or sand boil phenomenon. Thus, it seems necessary to calculate the pressure applied to the contact surface of the dam. One method for preventing piping phenomenon, reduction in exit gradient as well as decrease of uplift force beneath diversion dams includes implementation of weep hole. This study aims to study the effect of radius, depth and location of pipe drains under stilling basin upon how much uplift force decreases. The benefit of this study in agricultural field for soil and water engineers is to have a safe design of lined canals, weirs or diversion dams. To do this, numerical simulation of Tabriz diversion dam with Geo-Studio software was carried out. Results showed that application of drain pipe under the structure reduced uplift force respect to without drain under the structure. Increasing of drain radius; caused reduction of uplift pressure more but increased of seepage flow slightly. Installation of drain in upper part of stilling basin had a tendency to decrease uplift pressure more. Existence of drain near the stilling basin bottom caused in more reducing of uplift pressure than of installation of it in deeper depth

  8. Thermokarst lakes, drainage, and drained basins

    Science.gov (United States)

    Grosse, G.; Jones, B.; Arp, C.; Shroder, John F.

    2013-01-01

    Thermokarst lakes and drained lake basins are widespread in Arctic and sub-Arctic permafrost lowlands with ice-rich sediments. Thermokarst lake formation is a dominant mode of permafrost degradation and is linked to surface disturbance, subsequent melting of ground ice, surface subsidence, water impoundment, and positive feedbacks between lake growth and permafrost thaw, whereas lake drainage generally results in local permafrost aggradation. Thermokarst lakes characteristically have unique limnological, morphological, and biogeochemical characteristics that are closely tied to cold-climate conditions and permafrost properties. Thermokarst lakes also have a tendency toward complete or partial drainage through permafrost degradation and erosion. Thermokarst lake dynamics strongly affect the development of landscape geomorphology, hydrology, and the habitat characteristic of permafrost lowlands.

  9. Fine root production at drained peatland sites

    Energy Technology Data Exchange (ETDEWEB)

    Finer, L. [Finnish Forest Research Inst. (Finland). Joensuu Research Station; Laine, J. [Helsinki Univ. (Finland). Dept. of Forest Ecology

    1996-12-31

    The preliminary results of the Finnish project `Carbon balance of peatlands and climate change` show that fine roots play an important role in carbon cycling on peat soils. After drainage the roots of mire species are gradually replaced by the roots of trees and other forest species. Pine fine root biomass reaches a maximum level by the time of crown closure, some 20 years after drainage on pine mire. The aim of this study is to compare the results of the sequential coring method and the ingrowth bag method used for estimating fine root production on three drained peatland sites of different fertility. The results are preliminary and continuation to the work done in the study Pine root production on drained peatlands, which is part of the Finnish project `Carbon cycling on peatlands and climate change`. In this study the fine root biomass was greater on the poor site than on the rich sites. Pine fine root production increased with the decrease in fertility. Root turnover and the production of field layer species were greater on the rich sites than on the poor site. The results suggested that the in growth bag method measured more root activity than the magnitude of production. More than two growing seasons would have been needed to balance the root dynamics in the in growth bags with the surrounding soil. That time would probably have been longer on the poor site than on the rich ones and longer for pine and field layer consisting of dwarf shrubs than for field layer consisting of sedge like species and birch. (11 refs.)

  10. Importance of including small-scale tile drain discharge in the calibration of a coupled groundwater-surface water catchment model

    DEFF Research Database (Denmark)

    Hansen, Anne Lausten; Refsgaard, Jens Christian; Christensen, Britt Stenhøj Baun

    2013-01-01

    . The results showed that including tile drain data in the calibration of the catchment model improved its general performance for hydraulic heads and stream discharges. However, the model failed to correctly describe the local-scale dynamics of the tile drain discharges, and, furthermore, including the drain...... data in the calibration did not improve the small-scale spatial dynamics. This is mainly believed to be caused by the model's inadequate simulation of local spatial dynamics in hydraulic heads, which we argue is likely due to the lack of sufficient heterogeneity in the geological model.......To use a catchment-scale model to delineate areas with high and low denitrification capacities in the saturated zone of a catchment, the model must have an accurate spatial description of both general large-scale flow patterns on catchment scale and small-scale flow patterns locally within...

  11. Brain drain from developing countries: how can brain drain be converted into wisdom gain?

    OpenAIRE

    Dodani, Sunita; LaPorte, Ronald E

    2005-01-01

    Brain drain is defined as the migration of health personnel in search of the better standard of living and quality of life, higher salaries, access to advanced technology and more stable political conditions in different places worldwide. This migration of health professionals for better opportunities, both within countries and across international borders, is of growing concern worldwide because of its impact on health systems in developing countries. Why do talented people leave their count...

  12. Modeling Subsurface Storm and Tile Drain Systems in GSSHA with SUPERLINK

    Science.gov (United States)

    2014-09-01

    discharge to overland flow. ERDC/CHL TR-14-11 12 3 Tile Drains As described in Chapter 2, pipes in SUPERLINK represent both storm drains and tile...stream network. Storm drains may also function as tile drains as long as saturated groundwater is being simulated in the GSSHA model. The input...requirements for storm drains and tile drains are the same; only the value of hydraulic conductivity for the pipe differs between storm and tile drains

  13. Influence of Hudiara Drain Water Irrigation on Trace Elements Load ...

    African Journals Online (AJOL)

    MICHAEL

    Demand (COD) and Biological Oxygen Demand (BOD) requirements of Drain water were also found higher than the. National Environmental Quality Standards (NEQS) established under the Pakistan Environmental Protection Act, 1997. It was concluded that continuous use of untreated drain's water is not suitable for ...

  14. Drains after Thyroidectomy for Benign Thyroid Disorders; Are ...

    African Journals Online (AJOL)

    hematoma or seroma) and also for detection of continuing bleeding. This is aimed at ... None of the patients in the non-drain group had post-surgical wound infection whereas four (9%) of those who had drains developed wound sepsis.

  15. The stable stiffness triangle - drained sand during deformation cycles

    DEFF Research Database (Denmark)

    Sabaliauskas, Tomas; Ibsen, Lars Bo

    2017-01-01

    Cyclic, drained sand stiffness was observed using the Danish triaxial appa- ratus. New, deformation dependant soil property (the stable stiffness triangle) was detected. Using the the stable stiffness triangle, secant stiffness of drained sand was plausible to predict (and control) even during...

  16. The health workforce crisis: the brain drain scourge.

    Science.gov (United States)

    Ike, Samuel O

    2007-01-01

    The magnitude of the health workforce crisis engendered by brain drain particularly in Africa, and nay more especially Nigeria, has been assuming increasingly alarming proportions in the past three decades. The challenge it poses in meeting the manpower needs in the healthcare sector as well as in the larger economy of the sending countries is enormous. This paper thus sets out to highlight the scope of this brain drain, its effects and the reasons sustaining it, as well as makes concrete suggestions to help stern the tide. A review of the literature on brain drain with particular emphasis on the health workforce sector was done, with focus on Africa, and specifically Nigeria. Literature search was done using mainly the Medline, as well as local journals. The historical perspectives, with the scope of external and internal brain drain are explored. The glaring effects of brain drain both in the global workforce terrain and specifically in the health sectors are portrayed. The countries affected most and the reasons for brain drain are outlined. Strategic steps to redress the brain drain crisis are proffered in this paper. The health workforce crisis resulting from brain drain must be brought to the front-burner of strategic policy decisions leading to paradigm shift in political, social and economic conditions that would serve as incentives to curb the scourge.

  17. Rethinking "Brain Drain" in the Era of Globalisation

    Science.gov (United States)

    Rizvi, Fazal

    2005-01-01

    This paper discusses a range of issues concerning the idea of "brain drain" within the context of recent thinking on transnational mobility. It argues that the traditional analyses of brain drain are not sufficient, and that we can usefully approach the topic from a postcolonial perspective concerned with issues of identity, national…

  18. A new specifically designed forceps for chest drain insertion.

    LENUS (Irish Health Repository)

    Andrews, Emmet

    2012-02-03

    Insertion of a chest drain can be associated with serious complications. It is recommended that the drain is inserted with blunt dissection through the chest wall but there is no specific instrument to aid this task. We describe a new reusable forceps that has been designed specifically to facilitate the insertion of chest drains.A feasibility study of its use in patients who required a chest drain as part of elective cardiothoracic operations was undertaken. The primary end-point was successful and accurate placement of the drain. The operators also completed a questionnaire rating defined aspects of the procedure. The new instrument was used to insert the chest drain in 30 patients (19 male, 11 female; median age 61.5 years (range 16-81 years)). The drain was inserted successfully without the trocar in all cases and there were no complications. Use of the instrument rated as significantly easier relative to experience of previous techniques in all specified aspects. The new device can be used to insert intercostal chest drains safely and efficiently without using the trocar or any other instrument.

  19. Influence of Hudiara Drain Water Irrigation on Trace Elements Load ...

    African Journals Online (AJOL)

    cultivated area along the Drain by lifting the drain's water through electric pumps, peter engines and tractor driven devices. The density of tubewells is 7 pumps per kilometres for irrigating the farmer's fields and it is increasing day by day. Three points were selected for sampling the vegetables along the 54.6 km stretch of ...

  20. Late sensory changes following chest drain insertion during thoracotomy

    DEFF Research Database (Denmark)

    Wildgaard, K; Ringsted, T K; Ravn, J

    2013-01-01

    ) patients, in regard to pain and sensory dysfunction. METHODS: We quantified thermal and pressure thresholds on both the chest drain side and the contralateral side in 11 PTPS patients and 10 pain-free post-thoracotomy patients 33 months after the thoracotomy. On average, each patient had two chest drains...

  1. Analysis of three-dimensional transient seepage into ditch drains ...

    Indian Academy of Sciences (India)

    -dependent three-dimensional seepage into ditch drains from a flat, homogeneous and anisotropic ponded field of finite size,the field being assumed to be surrounded on all its vertical faces by ditch drains with unequal water level heights in ...

  2. Horner's syndrome caused by an intercostal chest drain.

    OpenAIRE

    Campbell, P.; Neil, T; Wake, P. N.

    1989-01-01

    Horner's syndrome occurred in a young woman as a complication of the treatment of a traumatic pneumothorax with an intercostal drain. The nerve damage probably occurred when the lung had fully re-expanded, pressing the tip of the intercostal drain, lying at the apex of the pleural cavity, on to the sympathetic chain.

  3. Use of modflow drain package for simulating inter-basin transfer in abandoned coal mines

    Science.gov (United States)

    Kozar, Mark D.; McCoy, Kurt J.

    2017-01-01

    Simulation of groundwater flow in abandoned mines is difficult, especially where flux to and from mines is unknown or poorly quantified, and inter-basin transfer of groundwater occurs. A 3-year study was conducted in the Elkhorn area, West Virginia to better understand groundwater-flow processes and inter-basin transfer in above drainage abandoned coal mines. The study area was specifically selected, as all mines are located above the elevation of tributary receiving streams, to allow accurate measurements of discharge from mine portals and tributaries for groundwater model calibration. Abandoned mine workings were simulated in several ways, initially as a layer of high hydraulic conductivity bounded by lower permeability rock in adjacent strata, and secondly as rows of higher hydraulic conductivity embedded within a lower hydraulic conductivity coal aquifer matrix. Regardless of the hydraulic conductivity assigned to mine workings, neither approach to simulate mine workings could accurately reproduce the inter-basin transfer of groundwater from adjacent watersheds. To resolve the problem, a third approach was developed. The MODFLOW DRAIN package was used to simulate seepage into and through mine workings discharging water under unconfined conditions to Elkhorn Creek, North Fork, and tributaries of the Bluestone River. Drain nodes were embedded in a matrix of uniform hydraulic conductivity cells that represented the coal mine aquifer. Drain heads were empirically defined from well observations, and elevations were based on structure contours for the Pocahontas No. 3 mine workings. Use of the DRAIN package to simulate mine workings as an internal boundary condition resolved the inter-basin transfer problem, and effectively simulated a shift from a topographic- dominated to a dip-dominated flow system, by dewatering overlying unmined strata and shifting the groundwater drainage divide up dip within the Pocahontas No. 3 coal seam several kilometers into the adjacent

  4. Head Lice

    Science.gov (United States)

    ... 1044-1047. Canyon, DV, Speare R, et al . “Spatial and kinetic factors for the transfer of head ... for children. Natural products can give parents false sense of safety If using a natural product or ...

  5. Design criteria Drain Rerouting Project 93-OR-EW-2

    Energy Technology Data Exchange (ETDEWEB)

    1993-04-01

    This document contains the design criteria to be used by the architect-engineer (A--E) in the performance of Title I and II design for the Drain Rerouting Project. The Drain Rerouting project at the US Department of Energy`s (DOE) Oak Ridge Reservation in Oak Ridge, Tennessee will provide the Y-12 Plant with the capability to reroute particular drains within buildings 9202, 9203 and 9995. Process drains that are presently connected to the storm sewer shall be routed to the sanitary sewer to ensure that any objectionable material inadvertently discharged into process drains will not discharge to East Fork Popular Creek (EFPC) without treatment. The project will also facilitate compliance with the Y-12 Plant`s National Pollutant Discharge Elimination System (NPDES) discharge permit and allow for future pretreatment of once-through coolant.

  6. Nitrate dynamics in artificially drained nested watersheds

    Science.gov (United States)

    Billy, C.; Birgand, F.; Sebilo, M.; Billen, G.; Tournebize, J.; Kao, C.

    There is concern that subsurface drainage, by destroying or by-passing active denitrification areas, may prevent nitrate retention processes and enhance nitrate contamination of surface water by agriculture. To address this question, we studied the flow and concentration signatures of drainage waters and their transformations in a series of 5 nested watersheds, from 1 to 100 km 2 area, in the Brie region near Paris (France). At all scales, nitrate concentrations are generally higher during the winter drainage season compared to the low flow periods (late spring to early fall). High nitrate concentrations characterizing drainage waters are visible at the 1st, 2nd and 3rd stream order but are “diluted” by surface runoff from forested zones and buffered by groundwater contributions. The analysis of nitrate chemographs and nitrate budgets established for the different nested watersheds show significant nitrogen retention. Isotopic measurements indicate that the nitrate pool is enriched in δ 15N- NO3- as its concentration decreases. Direct estimation of benthic denitrification with benthic chambers allowed concluding that benthic denitrification is not the only retention mechanism and that “underground” denitrification, affecting nitrate on its way from the base of the root zone down to the limit of the river bed, may in fact dominate nitrogen retention processes even in this intensively drained watershed.

  7. LIGHT regulates inflamed draining lymph node hypertrophy

    Science.gov (United States)

    Zhu, Mingzhao; Yang, Yajun; Wang, Yugang; Wang, Zhongnan; Fu, Yang-Xin

    2011-01-01

    Lymph node (LN) hypertrophy, the increased cellularity of LNs, is the major indication of the initiation and expansion of the immune response against infection, vaccination, cancer or autoimmunity. The mechanisms underlying LN hypertrophy remain poorly defined. Here, we demonstrate that LIGHT (TNFSF14) is a novel factor essential for LN hypertrophy after CFA immunization. Mechanistically, LIGHT is required for the influx of lymphocytes into but not egress out of LNs. In addition, LIGHT is required for DC migration from the skin to draining LNs. Compared with WT mice, LIGHT−/− mice express lower levels of chemokines in skin and addressins in LN vascular endothelial cells after CFA immunization. We unexpectedly observed that LIGHT from radioresistant rather than radiosensitive cells, likely Langerhans cells, is required for LN hypertrophy. Importantly, antigen-specific T cell responses were impaired in DLN of LIGHT−/− mice, suggesting the importance of LIGHT regulation of LN hypertrophy in the generation of an adaptive immune response. Collectively, our data reveal a novel cellular and molecular mechanism for the regulation of LN hypertrophy and its potential impact on the generation of an optimal adaptive immune response. PMID:21572030

  8. Field experiments to evaluate nitrate-leaching from drained agriculturally used areas

    Science.gov (United States)

    Bednorz, Denise; Tauchnitz, Nadine; Christen, Olaf; Rupp, Holger; Meissner, Ralph

    2016-04-01

    Agricultural land use is one of the main sources for diffuse nitrogen (N) inputs into surface- and groundwater. To fulfill the objectives of the European water protection policy it is mandatory to optimize agricultural management and to adopt it to site specific conditions. N present in soil is dominated by organic N, and after mineralization inorganic plant available N, obtaining the components ammonia and nitrate (NO3-N). In the environment, NO3-N occurs as the negatively charged ion NO3- which is generally solved. Thus, NO3-N is the major N-species in waters, whereas its transport is directly influenced by the flow regime. In dependence of soil type and meteorological conditions, subsurface drainage was often installed to prevent water logged zones as a requirement for agricultural use. But drainage systems were often discussed as one of the main sources for NO3-N inputs into surface water due to temporary high discharge rates and short residence time of soil water resulting in limited conditions for NO3-N degradation via denitrification. In the study presented herein, two adjacent tile-drained agriculturally used areas with adjusted agronomic conditions but different soil properties were investigated regarding their flow regime and their N-kinetic from 11/1/2013 until 10/31/2015. Both fields obtained the same size and drainage network (drain depth 0.8 m, gab distance 10 m). Field I was influenced by confined groundwater conditions due to an alternating strata of sandy and loamy layers. Field II was impermeable from a depth of one meter, showing a backwater influenced flow regime. The temporal course of soil moisture (35, 60 and 85 cm depth), drain rate as well as ground- and backwater head was registered continuously at both sites. Furthermore NH4-N- and NO3-N-concentrations (cNO3-N) in each compartment were measured. The experimental results showed that field I revealed significantly lower discharged drain rates and NO3-N-loads (17.1 mm and 2.5 kg N

  9. The Critical Height of a Liquid Being Drained from the Tank with Bell-Mouth Drain Port

    Directory of Open Access Journals (Sweden)

    J. Mohammadi

    2012-01-01

    Full Text Available Vortexing occurs during draining of liquid from tanks. We studied the critical height of a liquid being drained from tank, that is, the liquid height at the moment when the air-core vortex reaches to the drain port. We firstly performed some experiments for determining the critical height, and then based upon the information obtained from the experiments; a simple analytical expression was derived to predict the critical height. The experimental results show that the vortex suppressor, which is suggested in the present paper, could effectively reduce the strength of vortex and consequently reduce the critical height. The results also show that the new analytical expression can predict the critical height with less than 20% error when vortex suppressor is used. To the best of our knowledge, draining from tanks with bell-mouth drain ports has not been paid attention to by other authors.

  10. A novel thin-film transistor with step gate-overlapped lightly doped drain and raised source/drain design

    Science.gov (United States)

    Chien, Feng-Tso; Chen, Jian-Liang; Chen, Chien-Ming; Chen, Chii-Wen; Cheng, Ching-Hwa; Chiu, Hsien-Chin

    2017-11-01

    In this paper, a novel step gate-overlapped lightly doped drain (GOLDD) with raised source/drain (RSD) structure (SGORSD) is proposed for TFT electronic device application. The new SGORSD structure could obtain a low electric field at channel near the drain side owing to a step GOLDD design. Compared to the conventional device, the SGORSD TFT exhibits a better kink effect and higher breakdown performance due to the reduced drain electric field (D-EF). In addition, the leakage current also can be suppressed. Moreover, the device stability, such as the threshold voltage shift and drain current degradation under a high gate bias, is improved by the design of SGORSD structure. Therefore, this novel step GOLDD structure can be a promising design to be used in active-matrix flat panel electronics.

  11. "E" Heating Head

    Science.gov (United States)

    Fox, Robert L.; Swaim, Robert J.; Johnson, Samuel D.; Coultrip, Robert H.; Phillips, W. Morris; Copeland, Carl E.

    1994-01-01

    Two separate areas heated inductively for adhesive bonding in single operation. "E" heating head developed to satisfy need for fast-acting and reliable induction heating device. Used in attaching "high-hat" stiffeners to aircraft panels. Incorporates principles and circuitry of toroid joining gun. Width and length configured to provide variously sized heat zones, depending on bonding requirements. Lightweight, portable and provides rapid, reliable heating of dual areas in any environment. Well suited for flight-line and depot maintenance, and battlefield repair. Also useful in automotive assembly lines to strengthen automobile panels.

  12. Out of Our Heads! Four perspectives on the curation of an on-line exhibition of medically themed artwork by UK medical undergraduates

    Directory of Open Access Journals (Sweden)

    Trevor Thompson

    2010-11-01

    Full Text Available The Medical School at Bristol University is noted for offering, and in some instances requiring, its students to work creatively with medical themes. Students, artists, educationalists and a web designer have worked to create an on-line exhibition of the resulting creative output. This can be viewed at www.outofourheads.net. This site is a themed repository of poetry, prose, drawings, paintings, cartoons, films, music, dance and rap. Most works come with commentaries that can be as illuminating as the works they describe. The site invites comment and welcomes new postings from anyone connected to medicine. As an alternative to the conventional pedagogical report, and in keeping with the subject matter, in this paper we tell the story of this unique educational enterprise through the narratives of four of its principle architects. The ‘Teacher's Tale’, the ‘Designer's Tale’, the ‘Curator's Tale’ and the ‘Artist's Tale’ offer different, personal, tellings of how the site came to be. Each tale contains hypertext links to notable works on the site some of which have become teaching resources within the institution. This paper is of relevance to anyone who seeks to explore and champion the human insights of this privileged community.

  13. Out of Our Heads! Four perspectives on the curation of an on-line exhibition of medically themed artwork by UK medical undergraduates.

    Science.gov (United States)

    Thompson, Trevor; van de Klee, Danny; Lamont-Robinson, Catherine; Duffin, Will

    2010-11-26

    The Medical School at Bristol University is noted for offering, and in some instances requiring, its students to work creatively with medical themes. Students, artists, educationalists and a web designer have worked to create an on-line exhibition of the resulting creative output. This can be viewed at www.outofourheads.net. This site is a themed repository of poetry, prose, drawings, paintings, cartoons, films, music, dance and rap. Most works come with commentaries that can be as illuminating as the works they describe. The site invites comment and welcomes new postings from anyone connected to medicine. As an alternative to the conventional pedagogical report, and in keeping with the subject matter, in this paper we tell the story of this unique educational enterprise through the narratives of four of its principle architects. The 'Teacher's Tale', the 'Designer's Tale', the 'Curator's Tale' and the 'Artist's Tale' offer different, personal, tellings of how the site came to be. Each tale contains hypertext links to notable works on the site some of which have become teaching resources within the institution. This paper is of relevance to anyone who seeks to explore and champion the human insights of this privileged community.

  14. Three-dimensional computed tomographic evaluation of bilateral sagittal split osteotomy lingual fracture line and le fort I pterygomaxillary separation in orthognathic surgery using cadaver heads: ultrasonic osteotome versus conventional saw.

    Science.gov (United States)

    Dammous, Sophie; Dupont, Quentin; Gilles, Roland

    2015-06-01

    The purpose of this study was to observe the quality of the fracture line on the lingual side of the mandible after sagittal split osteotomy and the quality of pterygomaxillary separation after Le Fort I osteotomy using the BoneScalpel ultrasonic osteotome. Bimaxillary procedures, according to the standard protocol, were performed using 10 fresh cadaver heads. The ultrasonic osteotome was used in the study group, and a reciprocating saw was used in the control group. Three-dimensional reconstructions of postoperative computed tomographic scans were obtained. The lingual ramus fracture pattern and the pterygomaxillary separation pattern were observed, classified, and compared. Postoperative dissections of the skulls were performed to assess the integrity of the infra-alveolar nerve and the descending palatine artery. No significant differences were found in the cutting time of bone between the BoneScalpel and the sagittal saw. Of the sagittal split osteotomies in the study group, 90% showed a good pattern (vertical pattern of fracture line extending to the inferior border of the mandible running behind the mandibular canal) compared with 50% of the sagittal split osteotomies in the control group. Ideal separation of the pterygoid plates without fractures was observed in 80% of the Le Fort I osteotomies in the study group compared with 50% of the osteotomies in the control group. High-level fractures occurred in 30% of cases in the control group compared with none in the study group. The integrities of the infra-alveolar nerve and the descending palatine artery were preserved in all cases. Use of the ultrasonic BoneScalpel did not require more time than the conventional method. An improved pattern of lingual fracture lines in mandibular sagittal split osteotomy procedures and the pattern of pterygomaxillary separation in Le Fort I osteotomy procedures were observed. Copyright © 2015 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc

  15. Analytical model for vacuum consolidation incorporating soil disturbance caused by mandrel-driven drains

    National Research Council Canada - National Science Library

    Indraratna, Buddhima; Kelly, Richard; Perera, Darshana; Rujikiatkamjorn, Cholachat; Leroueil, Serge

    ... as a result of drain installation. The soil samples were obtained from various locations after drain installation to determine the characteristics of soil surrounding the vertical drain in terms of compressibility and permeability...

  16. Sediment Mobilization in Ravines Draining Minnesota Cropland

    Science.gov (United States)

    Choquette, A. W.; Triplett, L.; Gran, K. B.

    2013-12-01

    In recent years, studies have found that Lake Pepin, a naturally-dammed lake on the Mississippi River on the border of Minnesota and Wisconsin, is filling in with sediment at an alarming rate. Most of this sediment comes from the Minnesota River, which contributes about 80% of all the sediment being deposited in Lake Pepin, even though it contains only 35% of the upstream area. This study focuses on understanding sediment derived from ravine erosion in a tributary of the Minnesota River basin through event monitoring of two ravines in the Le Sueur River watershed. Ravines represent one of the key sediment sources in the Le Sueur watershed, with sediment mobilized through ravine widening and headcutting. In addition, sediment may be mobilized through riverbank and bluff erosion and erosion of the topsoil. A major effort is underway to reduce the amount of sediment in the Minnesota River and Lake Pepin, so we must discover what is causing the sediment to be mobilized and when. Dominant land use in the area is agricultural with over 90% of the crops consisting of row crops. Field drainage in these agricultural areas is heavily influenced by the installation of drainage ditches and drain tile. While this has increased crop yield, it has altered the natural drainage of the area. Southern Minnesota is covered by a thick layer of glacial till allowing the landscape to rapidly respond to hydrologic conditions within a relatively short amount of time, and those changes could include ravine widening or elongation. To better understand how ravines respond to different hydrologic events, we monitored ravines over the course of one monitoring season. From April-October 2013, three Sigma 930 automated samplers measured discharge and collected water samples for total suspended sediment analysis at three sites in two ravines. We tested whether the volume, intensity or seasonality of precipitation events is most important in mobilizing sediment in the ravines. Data are being

  17. Ethics and policy of medical brain drain: a review.

    Science.gov (United States)

    Kollar, Eszter; Buyx, Alena

    2013-10-25

    Health-worker migration, commonly called "medical brain drain", refers to the mass migration of trained and skilled health professionals (doctors, nurses, midwives) from low-income to high-income countries. This is currently leaving a significant number of poor countries, particularly in sub-Saharan Africa, with critical staff shortages in the healthcare sector. A broad consensus exists that, where medical brain drain exacerbates such shortages, it is unethical, and this review presents the main arguments underpinning this view. Notwithstanding the general agreement, which policies are justifiable on ethical grounds to tackle brain drain and how best to go about implementing them remains controversial. The review offers a discussion of the specific ethical issues that have to be taken into account when deciding which policy measures to prioritise and suggests a strategy of policy implementation to address medical brain drain as a matter of urgency.

  18. The Hunter Drain Stillwater National Wildlife Refuge Fallon, Nevada

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This document outlines water quality concerns related to the operation of the Hunter Drain located in the vicinity of the Stillwater National Wildlife Refuge. This...

  19. Development of Charge Drain Coatings: Final CRADA Report

    Energy Technology Data Exchange (ETDEWEB)

    Elam, Jeffrey W. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2017-01-17

    The primary goal of this CRADA project was to develop and optimize tunable resistive coatings prepared by atomic layer deposition (ALD) for use as charge-drain coatings on the KLA-Tencor digital pattern generators (DPGs).

  20. Head Start.

    Science.gov (United States)

    Greenman, Geri

    2000-01-01

    Discusses an art project in which students created drawings of mop heads. Explains that the approach of drawing was more important than the subject. States that the students used the chiaroscuro technique, used by Rembrandt and Caravaggio, in which light appears out of the darkness. (CMK)

  1. Characteristics of the overflow pollution of storm drains with inappropriate sewage entry.

    Science.gov (United States)

    Yin, Hailong; Lu, Yi; Xu, Zuxin; Li, Huaizheng; Schwegler, Benedict R

    2017-02-01

    To probe the overflow pollution of separate storm drains with inappropriate sewage entries, in terms of the relationship between sewage entries and the corresponding dry-weather and wet-weather overflow, the monitoring activities were conducted in a storm drainage system in the Shanghai downtown area (374 ha). In this study site, samples from inappropriately entered dry-weather sewage and the overflow due to storm pumps operation on dry-weather and wet-weather days were collected and then monitored for six water quality constituents. It was found that overflow concentrations of dry-weather period could be higher than those of wet-weather period; under wet-weather period, the overflow concentrations of storm drains were close to or even higher than that of combined sewers. Relatively strong first flush mostly occurred under heavy rain that satisfied critical rainfall amount, maximum rainfall intensity, and maximum pumping discharge, while almost no first flush effect or only weak first flush effect was found for the other rainfall events. Such phenomenon was attributed to lower in-line pipe storage as compared to that of the combined sewers, and serious sediment accumulation within the storm pipes due to sewage entry. For this kind of system, treating a continuous overflow rate is a better strategy than treating the maximum amount of early part of the overflow. Correcting the key inappropriate sewage entries into storm drains should also be focused.

  2. Brain drain from developing countries: how can brain drain be converted into wisdom gain?

    Science.gov (United States)

    Dodani, Sunita; LaPorte, Ronald E

    2005-11-01

    Brain drain is defined as the migration of health personnel in search of the better standard of living and quality of life, higher salaries, access to advanced technology and more stable political conditions in different places worldwide. This migration of health professionals for better opportunities, both within countries and across international borders, is of growing concern worldwide because of its impact on health systems in developing countries. Why do talented people leave their countries and go abroad? What are the consequences of such migrations especially on the educational sector? What policies can be adopted to stem such movements from developing countries to developed countries? This article seeks to raise questions, identify key issues and provide solutions which would enable immigrant health professionals to share their knowledge, skills and innovative capacities and thereby enhancing the economic development of their countries.

  3. An iterative method for estimating solute travel times to ditch drains under steady recharge and ponded conditions

    Science.gov (United States)

    Barua, Gautam; Patidar, M. K.

    2017-03-01

    An iterative procedure is worked out for estimating solute travel times in a subsurface system by making use of the velocity and streamline distributions pertinent to the system. The developed method is then being applied to study the solute travel times to ditch drains originating from a field being subjected to a uniform (1) recharge and (2) ponding field over the surface of the soil. For case (1), both single and layered soils are being considered to estimate the travel times. The developed mathematical procedure is simple to use, robust, reasonably accurate even if being used with a lesser division of a streamline and completely eliminates the necessity of determination of any integrals for estimating the travel times—integrals which, in the methods generally been employed for estimating the travel times from steady-state analytical groundwater models, would otherwise need be evaluated. The study shows that travel times of water particles traversing through a layered soil being subjected to a uniform recharge at the surface are sensitive to the directional conductivities, anisotropy ratio (defined here as the ratio between horizontal and vertical hydraulic conductivities of soil) and thickness of individual layers of a soil profile as well as to the magnitude of the steady-state recharge on the surface of the soil. For the ponded drainage scenarios also, directional conductivities and thickness of a soil profile, extent of partial penetration and width of the ditch drains, levels of water head at the surface of the soil as well as on the ditches are observed to influence the travel times in a noticeable way. The proposed method is important as it provides simple and accurate estimations of migration times of pollutants to subsurface drains under different drainage situations; it can also be used to assess the time of reclamation of a salt-affected or waterlogged soil being drained by a network of subsurface drains being installed for the purpose from the

  4. Nurses’ Knowledge Levels of Chest Drain Management: A Descriptive Study

    Directory of Open Access Journals (Sweden)

    Merve Tarhan

    2016-12-01

    Full Text Available Objective: The physician is responsible for inserting one or more chest tubes into the pleural space or the mediastinal space and connecting them to an appropriate drainage system. When the general principles about care of patients with chest drains were implemented correctly and effectively by nurses, nurse will contribute to accelerate the healing process of patients. In this context, the aim of this study was to determine the nurses’ level of knowledge regarding the care of patients with chest drains. Methods: The study was conducted with 153 nurses who worked in a chest diseases and thoracic surgery hospital in July 2014. Questionnaire form of 35 questions prepared by investigators was used to collect data. For the analysis of results, frequency tests, independent sample t-test and oneway ANOVA test were used. Results: 69.3% of nurses stated that they had obtained information from colleguages. 35.3% considered their knowledge about chest drain management to be inadequate. 55.6% scored 13 points and above from knowledge questionnaire about chest drain management. There were statistically significant difference between knowledge level and educational background, clinic work type, working unit, years of professional experience and institutional experience, frequency of contact patients with chest drain and perception of knowledge level (p<0.05. Conclusion: Results of this study indicate that lack of evidence-based nursing care and insufficient training has resulted in uncertainty and knowledge deficit in important aspects of chest drain care. It can be concluded that nurses receive training needs and training protocols are about chest drain management.

  5. Development of a 3D-printed external ventricular drain placement simulator: technical note.

    Science.gov (United States)

    Tai, Bruce L; Rooney, Deborah; Stephenson, Francesca; Liao, Peng-Siang; Sagher, Oren; Shih, Albert J; Savastano, Luis E

    2015-10-01

    In this paper, the authors present a physical model developed to simulate accurate external ventricular drain (EVD) placement with realistic haptic and visual feedbacks to serve as a platform for complete procedural training. Insertion of an EVD via ventriculostomy is a common neurosurgical procedure used to monitor intracranial pressures and/or drain CSF. Currently, realistic training tools are scarce and mainly limited to virtual reality simulation systems. The use of 3D printing technology enables the development of realistic anatomical structures and customized design for physical simulators. In this study, the authors used the advantages of 3D printing to directly build the model geometry from stealth head CT scans and build a phantom brain mold based on 3D scans of a plastinated human brain. The resultant simulator provides realistic haptic feedback during a procedure, with visualization of catheter trajectory and fluid drainage. A multiinstitutional survey was also used to prove content validity of the simulator. With minor refinement, this simulator is expected to be a cost-effective tool for training neurosurgical residents in EVD placement.

  6. Is HEADS in our heads?

    DEFF Research Database (Denmark)

    Boisen, Kirsten A; Hertz, Pernille Grarup; Blix, Charlotte

    2016-01-01

    BACKGROUND: Outpatient clinic visits are a window of opportunity to address health risk behaviors and promote a healthier lifestyle among young people. The HEADS (Home, Education, Eating, Activities, Drugs [i.e. substance use including tobacco, alcohol, and illegal drugs], Sexuality [including...... contraception], Safety, Self-harm) interview is a feasible way of exploring health risk behaviors and resilience. OBJECTIVE: The purpose of this study was to evaluate how often HEADS topics were addressed according to young patients and staff in pediatric and adult outpatient clinics. METHODS: We conducted...... care professionals participated. We found only small reported differences between staff and young patients regarding whether home, education, and activity were addressed. However, staff reported twice the rate of addressing smoking, alcohol, illegal drugs, sexuality, and contraception compared to young...

  7. Drain Site Hernia in an Adult: A Case Report | Makama | West ...

    African Journals Online (AJOL)

    BACKGROUND: Surgical drains, as useful as they are, have been noted not to be without complications. Small bowel herniation through a previous drain site is a rare complication of abdominal drain insertion. OBJECTIVE: To report a case of strangulated hernia through a drain site. METHODS: A 46-year-old civil servant ...

  8. On the use of drains in orthopedic and trauma | Lawal | Nigerian ...

    African Journals Online (AJOL)

    Those patients whose wounds were drained had no need for drain change thus making the wound care less eventful. Conclusion: Postoperative wound drains make for neat postoperative period with less tissue swelling. There was no statistically significant differences between the drained and undrained wounds in terms of ...

  9. Viscosity dependent dual-permeability modeling of liquid manure movement in layered, macroporous, tile drained soil

    Science.gov (United States)

    Frey, Steven K.; Rudolph, David L.; Lapen, David R.; Ball Coelho, Bonnie R.

    2012-06-01

    A scarcity of information exists on how physical processes govern the movement of liquid manure, or other viscous fluids, through layered macroporous soils. To elucidate these complex flow and transport phenomena, a viscosity dependent, two-dimensional dual-permeability model that considers macropore anisotropy is employed to simulate field experiments where liquid swine manure (LSM) was applied to silt loam with both a soil crust and plowpan layer present. Using data from the field experiment as a benchmark, the model was used to predict nutrient (NH4-N and total P) breakthrough to tile drains; and to assess the influence of reduced permeability crust and plowpan layers, and fluid viscosity, on solute movement within 48 h of LSM application. Results demonstrate the importance of viscosity on flow and transport in macroporous soils. By increasing LSM viscosity, nutrient breakthrough to tile drains can be greatly reduced, and near surface nutrient retention can increase. The presence of a nonmacroporous soil crust layer can also lead to reduced nutrient concentrations in tile discharge by reducing pressure heads in the underlying A-horizon soil matrix, resulting in reduced macropore flow; whereas a low permeability plowpan layer at the base of the A horizon can increase pressure heads in the A-horizon soil matrix and lead to increased macropore flow. Multiple target point parameter sensitivity analysis revealed that relative parameter sensitivity can be a transient characteristic, and that hydraulic properties of the A and B horizon tend to exhibit their greatest influence over the respective early and late time solute breakthrough characteristics.

  10. Thoracoscopic pulmonary wedge resection without post-operative chest drain

    DEFF Research Database (Denmark)

    Holbek, Bo Laksafoss; Hansen, Henrik Jessen; Kehlet, Henrik

    2016-01-01

    effusion and coagulopathy. Chest X-rays were done twice on the day of surgery. 30-day complications were compiled from patient records. RESULTS: 49 patients underwent 51 unilateral VATS wedge resections without using a post-operative chest drain. No patient required reinsertion of a chest drain. 30 (59...... %) patients had a pneumothorax of mean size 12 ± 12 mm on supine 8-h post-operative X-ray for which the majority resolved spontaneously within 2-week control. There were no complications on 30-day follow-up. Median length of stay was 1 day. CONCLUSIONS: The results support that VATS wedge resection...... for pulmonary nodules without a post-operative chest drain may be safe in a selected group of patients....

  11. Comparison of drain clamp after bilateral total knee arthroplasty.

    Science.gov (United States)

    Madadi, Firooz; Mehrvarz, Amir Sarshekeh; Madadi, Firoozeh; Boreiri, Majid; Abachizadeh, Kambiz; Ershadi, Ali

    2010-12-01

    Suction drains provide an easy and feasible method for controlling hemorrhage after total knee arthroplasty. However, there has been no compromise regarding the optimum clamping time for these drains. We conducted a randomized clinical trial in 50 patients to compare 12-hour drain clamping and continuous drainage after total knee arthroplasty in terms of wound complications, blood loss, and articular arc of motion. To eliminate any other factor except duration of clamping, we chose to compare only knees belonging to a single patient and to restrict the study to those knees undergoing surgery due to osteoarthritis. From a total of 100 knees (50 patients) studied, the 12-hour-clamping method resulted in a significantly smaller amount of postoperative blood loss (p < 0.001). The passive ranges of motion and wound complications were not significantly different between the two groups.

  12. Predicting artificailly drained areas by means of selective model ensemble

    DEFF Research Database (Denmark)

    Møller, Anders Bjørn; Beucher, Amélie; Iversen, Bo Vangsø

    produced with one of these approaches, a better prediction can be achieved by combining the predictions of several models (Caruana et al., 2004, Sollich and Krogh, 1996). As more approaches become available, the importance of the method used for selecting the models for use in the ensemble increases....... The study aims firstly to train a large number of models to predict the extent of artificially drained areas using various machine learning approaches. Secondly, the study will develop a method for selecting the models, which give a good prediction of artificially drained areas, when used in conjunction...... method, when selecting the models. In this way, the developed method should be able to produce a highly accurate and robust map of artificially drained areas within a limited span of time....

  13. Randomized Controlled Trial to Reduce Bacterial Colonization of Surgical Drains After Breast and Axillary Operations

    Science.gov (United States)

    Degnim, Amy C.; Scow, Jeffrey S.; Hoskin, Tanya L.; Miller, Joyce P.; Loprinzi, Margie; Boughey, Judy C.; Jakub, James W.; Throckmorton, Alyssa; Patel, Robin; Baddour, Larry M.

    2014-01-01

    Objective To determine if bacterial colonization of drains can be reduced by local antiseptic interventions. Summary Background Drains are a potential source of bacterial entry into surgical wounds and may contribute to surgical site infection (SSI) after breast surgery. Methods Following IRB approval, patients undergoing total mastectomy and/or axillary lymph node dissection were randomized to standard drain care (control) or drain antisepsis (treated). Standard drain care comprised twice daily cleansing with alcohol swabs. Antisepsis drain care included 1) a chlorhexidine disc at the drain exit site and 2) irrigation of the drain bulb twice daily with dilute sodium hypochlorite (Dakin’s) solution. Cultures results of drain fluid and tubing were compared between control and antisepsis groups. Results Overall, 100 patients with 125 drains completed the study with 48 patients (58 drains) in the control group and 52 patients (67 drains) in the antisepsis group. Cultures of drain bulb fluid at one week were positive (1+ or greater growth) in 66% (38/58) of control drains compared to 21% of antisepsis drains (14/67), (p=0.0001). Drain tubing cultures demonstrated >50 CFU in 19% (8/43) of control drains versus 0% (0/53) of treated drains (p=0.004). SSI was diagnosed in 6 patients (6%) - 5 patients in the control group and 1 patient in the antisepsis group (p=0.06). Conclusions Simple and inexpensive local antiseptic interventions with a chlorhexidine disc and hypochlorite solution reduce bacterial colonization of drains. Based on these data, further study of drain antisepsis and its potential impact on SSI rate is warranted. PMID:23518704

  14. Set-up errors and planning target volume margins in head and neck cancer radiotherapy: a clinical study of image guidance with on-line cone-beam computed tomography.

    Science.gov (United States)

    Dionisi, Francesco; Palazzi, Mauro Filippo; Bracco, Francesco; Brambilla, Maria Grazia; Carbonini, Claudia; Asnaghi, Diego Dario; Monti, Angelo Filippo; Torresin, Alberto

    2013-06-01

    Set-up errors represent a source of uncertainty in head and neck (H&N) cancer radiotherapy. The present study evaluated set-up accuracy with the use of cone-beam computed tomography (CBCT) in order to establish the proper clinical target volume (CTV) to planning target volume (PTV) margins to be adopted. Local set-up accuracy was analysed for 44 H&N cancer patients since the implementation of CBCT. An on-line correction protocol was adopted, with the first 3 scans used to correct systematic errors with a 3-mm action level. The overall mean displacement (M), the population systematic (Σ) and random (σ) errors and the 3D vector length were calculated. PTV margins were calculated according to the van Herk formula (2.5Σ + 0.7σ). A total of 420 CBCT scans were analysed. A systematic correction was needed in 43% of patients. The value of M was <1 mm in all directions; the values of Σ and σ ranged over 1-1.2 and 1.4-1.9 mm, respectively. Pre-correction PTV margins were 3.48, 4.08 and 4.33 mm along the 3 axes. The PTV margins calculated after online correction were <2.5 mm in all directions. Kilovoltage CBCT is effective in evaluating set-up accuracy in H&N patients. CTV-PTV margins of 5 mm are safe and are currently adopted at our centre; however, some special situations, such as re-irradiation or the close proximity of organs at risk and high-dose regions, could benefit from daily image registration and lower (i.e., 3 mm) margins.

  15. Rare bile duct anomaly: B3 duct draining to gallbladder

    Directory of Open Access Journals (Sweden)

    Seung Eun Lee

    2016-01-01

    Full Text Available A 10-year-old girl presented with recurrent right upper abdominal pain and dyspepsia. Magnetic resonance cholangiopancreatography revealed a dilated common channel of intrahepatic bile duct of segment 3 (B3 and segment 4 (B4 drained into the gallbladder directly. The patient underwent laparoscopic cholecystectomy and Roux-en Y hepaticojejunostomy (B3-jejunostomy. Among the anatomical variability of the biliary system, the cholecystohepatic ducts are controversial in existence and incidence. We report a very rare variant of a cholecystohepatic duct in which the B3 duct drained into gallbladder directly and to the best of our knowledge this is the first report.

  16. The African brain drain: causes and policy prescriptions.

    Science.gov (United States)

    Danso, K

    1995-01-01

    "This article analyzes the causes of the African Brain Drain. It also identifies policy prescriptions to stem the tide of the brain drain....The analysis shows that African governments should try to retain their skilled personnel by significantly improving their economies so as to provide the basic necessities of life to their people. African governments should also democratize their political institutions and respect individual human rights. Finally, they should create a conducive socio political environment for the skilled professional to operate, otherwise even the most patriotic of them would be tempted to emigrate." excerpt

  17. Study of drain-extended NMOS under electrostatic discharge stress in 28 nm and 40 nm CMOS process

    Science.gov (United States)

    Wang, Weihuai; Jin, Hao; Dong, Shurong; Zhong, Lei; Han, Yan

    2016-02-01

    Researches on the electrostatic discharge (ESD) performance of drain-extended NMOS (DeNMOS) under the state-of-the-art 28 nm and 40 nm bulk CMOS process are performed in this paper. Three distinguishing phases of avalanche breakdown stage, depletion region push-out stage and parasitic NPN turn on stage of the gate-grounded DeNMOS (GG-DeNMOS) fabricated under 28 nm CMOS process measured with transmission line pulsing (TLP) test are analyzed through TCAD simulations and tape-out silicon verification detailedly. Damage mechanisms and failure spots of GG-DeNMOS under both CMOS processes are thermal breakdown of drain junction. Improvements based on the basic structure adjustments can increase the GG-DeNMOS robustness from original 2.87 mA/μm to the highest 5.41 mA/μm. Under 40 nm process, parameter adjustments based on the basic structure have no significant benefits on the robustness improvements. By inserting P+ segments in the N+ implantation of drain or an entire P+ strip between the N+ implantation of drain and polysilicon gate to form the typical DeMOS-SCR (silicon-controlled rectifier) structure, the ESD robustness can be enhanced from 1.83 mA/μm to 8.79 mA/μm and 29.78 mA/μm, respectively.

  18. Surgical Drains: What the Resident Needs To Know | Makama ...

    African Journals Online (AJOL)

    Results: Drains remove content of body organs, secretion of body cavities and tissue fluids such as blood, serum, lymph and other body fluid that accumulate in wound bed after surgical procedures. Therefore, reduction of pressure to surgical site as well as adjacent organs, nerves and blood vessels, enhances wound ...

  19. Brain Drain: A Child's Brain on Poverty. Poverty Fact Sheet

    Science.gov (United States)

    Damron, Neil

    2015-01-01

    "Brain Drain: A Child's Brain on Poverty," released in March 2015 and prepared by intern Neil Damron, explores the brain's basic anatomy and recent research findings suggesting that poverty affects the brain development of infants and young children and the potential lifelong effects of the changes. The sheet draws from a variety of…

  20. Watershed Models for Predicting Nitrogen Loads from Artificially Drained Lands

    Science.gov (United States)

    R. Wayne Skaggs; George M. Chescheir; Glenn Fernandez; Devendra M. Amatya

    2003-01-01

    Non-point sources of pollutants originate at the field scale but water quality problems usually occur at the watershed or basin scale. This paper describes a series of models developed for poorly drained watersheds. The models use DRAINMOD to predict hydrology at the field scale and a range of methods to predict channel hydraulics and nitrogen transport. In-stream...

  1. Brain drain and capacity building in Africa | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2011-02-01

    Feb 1, 2011 ... In 25 years, Africa will be empty of brains.” That dire warning, from Dr Lalla Ben Barka of the UN Economic Commission for Africa (ECA), reflects the growing alarm over Africa's increasing exodus of human capital. Data on brain drain in Africa is scarce and inconsistent; however, statistics show a continent ...

  2. Emergency medicine program targets "brain drain" in Ethiopia ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    15 juil. 2014 ... "brain drain" in Ethiopia. Dr Dave MacKinnon gives a demonstration on casting to medical residents in Addis Ababa. Over the last three decades, 4,000 doctors have left Ethiopia for specialized training abroad. But very few return home to practice their specialty. Now, thanks to the Toronto-Addis Ababa ...

  3. Organic loss in drained wetland: managing the carbon footprint

    NARCIS (Netherlands)

    Durham, B.; van de Noort, R.; Martens, V.V.; Vorenhout, M.

    2012-01-01

    The recent installation of land drains at Star Carr, Yorkshire, UK, has been linked with loss of preservation quality in this important Mesolithic buried landscape, challenging the PARIS principle. Historically captured organic carbon, including organic artefacts, is being converted to soluble

  4. Brain drain or brain gain : The case of Suriname

    NARCIS (Netherlands)

    T.W. Dulam (Tina)

    2015-01-01

    markdownabstractAbstract Brain drain refers to the emigration of highly skilled individuals mostly from a less developed (home) to a developed country (destination) thereby reducing the capacity of the home country to generate welfare for its population. In the literature there is much written

  5. Short-channel drain current model for asymmetric heavily / lightly ...

    Indian Academy of Sciences (India)

    PRADIPTA DUTTA

    2017-07-29

    Jul 29, 2017 ... transistors (MOSFETs) is a good practice for semicon- ductor industry to achieve higher packing density and better circuit performance. But down-scaling has some disadvantages also. These small scaled devices suffer from various types of short channel effects like veloc- ity saturation, drain-induced ...

  6. A Study of Factors Influencing Brain Drain among Medical ...

    African Journals Online (AJOL)

    This economic situation deeply affected the medical groups that migration became the chorus of the medical personnel. This perennial situation made the study to examine the factors influencing brain drain among the medical personnel in Nigeria, using a selected University Teaching Hospital Complex as a case study.

  7. Reversing brain drain in Africa by engaging the diaspora ...

    African Journals Online (AJOL)

    The impacts of brain drain in Africa are phenomenal. In the lst five decades of the continent's political history, political and economic factors have collectively acted as push factors in the migration of young Africans from the continent. As such, reducing, reversing and mitigated the effects of emigration from Africa have been a ...

  8. Diasporic and Discursive Eruptions in the New Zealand Brain Drain.

    Science.gov (United States)

    Boshier, Roger

    2002-01-01

    Human and social capital discourses attempt to explain New Zealand's brain drain. Solutions related to each discourse involve offering incentives for returning or creating links so that expatriates can contribute to their homeland from abroad. Establishing such "diaspora networks" might be the role of adult education. (Contains 43…

  9. Does State Merit-Based Aid Stem Brain Drain?

    Science.gov (United States)

    Zhang, Liang; Ness, Erik C.

    2010-01-01

    In this study, the authors use college enrollment and migration data to test the brain drain hypothesis. Their results suggest that state merit scholarship programs do indeed stanch the migration of "best and brightest" students to other states. In the aggregate and on average, the implementation of state merit aid programs increases the…

  10. Moving Policy Forward: "Brain Drain" as a Wicked Problem

    Science.gov (United States)

    Logue, Danielle

    2009-01-01

    The mobility of scientists and the concerns surrounding "brain drain" are not new. Even in the Ptolemic dynasty, the first king set out to attract and influence the movements of scholars to shift the centre of learning from Athens to Alexandria. Yet after all this time, there is still much policy discourse and debate focused on attempting to…

  11. Brain Drain in Higher Education: Lost Hope or Opportunity?

    Science.gov (United States)

    Odhiambo, George

    2012-01-01

    The flight of human capital is a phenomenon that has been of concern to academics and development practitioners for decades but unfortunately, there is no systematic record of the number of skilled professionals that many African countries have continued to lose to the developed world. Termed the "brain drain", it represents the loss of…

  12. Can a brain drain be good for growth?

    NARCIS (Netherlands)

    Mountford, A.W.

    1995-01-01

    This paper shows how a brain drain - the emigration of agents with a relatively high level of human capital in an economy - can paradoxically increase the productivity of an economy where productivity is a function of the average level of human capital. The model uses Galor and Tsiddon's model of

  13. Peritoneal Drains in Perforated Appendicitis without Peritonitis: A ...

    African Journals Online (AJOL)

    Background: Appendicitis is recognized worldwide as the commonest surgical emergency. Its management becomes more challenging when the patient presents with perforated appendicitis In the western world To determine the value of peritoneal drains in patients operated with an appendicular pathology more advanced ...

  14. Xpand chest drain: assessing equivalence to current standard ...

    African Journals Online (AJOL)

    Background. Penetrating chest trauma is a leading cause of admission to South African emergency departments. The resultant pneumo-/haemothoraces are currently routinely treated by means of standard underwater bottle drainage. A South African company, Sinapi Biomedical, recently launched the Xpand chest drain.

  15. Drains after Thyroidectomy for Benign Thyroid Disorders; Are ...

    African Journals Online (AJOL)

    Drains after Thyroidectomy for Benign Thyroid Disorders; Are Associated With More Pain, Wound Infection and Prolonged Hospital Stay. ... The PDF file you selected should load here if your Web browser has a PDF reader plug-in installed (for example, a recent version of Adobe Acrobat Reader). If you would like more ...

  16. The syringe suction drain - A unique improvisation in rural plastic ...

    African Journals Online (AJOL)

    Background: Closed suction drains are often needed in surgical practice. However, they are luxury in rural plastic surgery practice. This study highlights how syringes have become a reliable substitute. Materials and methods: This is a prospective study of the surgical outcome of patient who had various plastic surgical ...

  17. Case Report: Supernumerary right renal vein draining inferior to the ...

    African Journals Online (AJOL)

    With recent increase in renal transplantations, renovascular reconstructions and imaging advances, meticulous knowledge of the normal and variant anatomy of the renal vasculature is important to avoid potential pitfalls. We report a case of an accessory renal vein arising from the right kidney, and draining into the inferior ...

  18. New SWAT tile drain equations: Modifications, Calibration, Validation, and Application

    Science.gov (United States)

    Subsurface tile drainage is a commonly used agricultural practice to enhance crop yield in poorly drained but highly productive soils in many other regions of the world. However, the presence of subsurface tile drainage systems also expedites the transport of nitrate-nitrogen (NO3-N) and other chemi...

  19. High drain amylase and lipase values predict post-operative ...

    African Journals Online (AJOL)

    Background: Post-operative pancreatitis is a severe complication after cyst excision with hepaticoenterostomy (CEHE) for choledochal cysts. The aim of this study was to examine the dynamic post-operative changes in drain amylase and lipase values after CEHE for choledochal cysts, and then compare these values with ...

  20. English and the Brain Drain : An Uncertain Relationship

    NARCIS (Netherlands)

    Houtkamp, C.

    2016-01-01

    In his book Linguistic Justice for Europe and the World, Van Parijs analyses in one of his chapters the brain drain from non-Anglophone to Anglophone countries, which hurts the economic development of the nonAnglophone states. Van Parijs deems it clear that English is a very important factor to

  1. Water balance of drained plantation watersheds in North Carolina

    Science.gov (United States)

    Johnny M. Grace; R. W. Skaggs

    2006-01-01

    A 3-year study to evaluate the effect of thinning on the hydrology of a drained loblolly pine (Pinus taeda L.) plantation was conducted in eastern North Carolina. The study utilized a paired watershed design with a 40-ha thinned watershed (WS5) and a 16-ha control watershed (WS2). Data from the field experiment conducted from 1999-2002 was used to...

  2. Domestic wastewater treatment with a vertical completely drained ...

    African Journals Online (AJOL)

    Domestic wastewater treatment with a vertical completely drained pilot scale constructed wetland planted with Amaranthus hybridus. ... +: 69%, PO4 3-: 67%) than in the control (NH4 +: 15%; PO4 3-: 56%). However the important oxidation of NH4 + to NO2 - and NO3 - provoked their accumulation in these beds filtrates than ...

  3. Xpand chest drain: assessing equivalence to current standard ...

    African Journals Online (AJOL)

    our current treatment modalities and search for more cost- effective means of treatment. Underwater seal drainage was first described by Playfair1 in 1875 and has become the standard form of chest drainage throughout the world. In South Africa the underwater drain. (UWD) is the most common device used for chest ...

  4. Studies on groundwater recharge through surface drains | Singh ...

    African Journals Online (AJOL)

    ... for the estimation of groundwater recharge through surface drains for both free flow as well as detained flow conditions. The Dupuit-Forchheimmer equation is solved using the Crank-Nicolson central finite difference scheme, to obtain the mound height matrix. The Gaussian elimination method was used to solve the matrix ...

  5. Head First 2D Geometry

    CERN Document Server

    Fallow), Stray

    2009-01-01

    Having trouble with geometry? Do Pi, The Pythagorean Theorem, and angle calculations just make your head spin? Relax. With Head First 2D Geometry, you'll master everything from triangles, quads and polygons to the time-saving secrets of similar and congruent angles -- and it'll be quick, painless, and fun. Through entertaining stories and practical examples from the world around you, this book takes you beyond boring problems. You'll actually use what you learn to make real-life decisions, like using angles and parallel lines to crack a mysterious CSI case. Put geometry to work for you, and

  6. Drain fistulography: Radiological sphincter identification in high anal fistulae. Drain-Fistulographie. Radiologische Sphinkteridentifikation bei hohen Analfisteln

    Energy Technology Data Exchange (ETDEWEB)

    Barton, P. (Abt. fuer Roentgendiagnostik, 1. Chirurgische Universitaetsklinik, Vienna (Austria)); Wunderlich, M. (Krankenhaus Hollabrunn (Austria). Chirurgische Abt.); Herbst, F. (1. Chirurgische Universitaetsklinik, Vienna (Austria)); Jantsch, H. (Abt. fuer Roentgendiagnostik, 1. Chirurgische Universitaetsklinik, Vienna (Austria)); Waneck, R. (Abt. fuer Roentgendiagnostik, 1. Chirurgische Universitaetsklinik, Vienna (Austria)); Lechner, G. (Abt. fuer Roentgendiagnostik, 1. Chirurgische Universitaetsklinik, Vienna (Austria))

    1993-07-01

    To warrant permanent surgical cure of high anal fistulae, while avoiding at the same time faecal incontinence due to inadvertent division of the puborectalis muscle, distinction between a trans- and suprasphincteric fistula track is essential. This differentiation is often crucial, since digital-rectal palpation and conventional fistulography tend to be unreliable. Therefore we developed a radiological technique of imaging the anorectal fistulous track, 'drain fistulography'. After silicon drainage of the fistula the contrast-visualization of anal canal, rectum and fistula drain allows to assess the topographic relation between fistula and anal sphincters as well as the sphincteric functional component above the fistula. A transsphincteric fistula track was demonstrated in 7 of 8 patients (5 with recurrent fistulae) by means of 'drain fistulography', permitting complete laying open of each fistula in a second operation. In one patient a supraphincteric fistula track was found and a 'mucosal flap repair' was carried out. After a mean observation time of 53 months all patients are perfectly continent and free of recurrence. The method of 'drain fistulography' is a valuable diagnostic tool to select the appropriate definitive surgical procedure in the treatment of high anal fistulae. (orig.)

  7. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... of the Head? What is CT Scanning of the Head? Computed tomography, more commonly known as a ... of page What are some common uses of the procedure? CT scanning of the head is typically ...

  8. Assessing the drain estuaries’ water quality in response to pollution abatement

    Directory of Open Access Journals (Sweden)

    Alaa Farouk Abukila

    2015-04-01

    Full Text Available To assess 12 years of pollution abatement efforts in all drain estuaries in Northern Egypt, which discharge to Northern Lakes and the Mediterranean Sea, this paper provides temporal trends in water quality indices from 2002 to 2013. For the estuary of 20 drains: one drain had insufficient data to analyze for trends (Burullus Drain, four drains had significant increase in water quality index (WQI score (Bahr ElBaqar Drain, Drain No. 1, Tabia Drain and No. 11 Drain, one drain had significant declination in water quality score over the tested time period (Ramsis Drain. While the rest (14 drains showed insignificant trend in either direction (improving or declining. Water quality fluctuated over that time period. On average, temporal changes in excursions of coliform count from their threshold can explain 83.3% of the temporal variability observed in water quality indicators monitored in all drain estuaries (38.9%% < R2 < 89.2%. Therefore, the most effective water quality variables among a set of variables affecting the WQI score was total coliform.

  9. Control of Culex quinquefasciatus in a storm drain system in Florida using attractive toxic sugar baits.

    Science.gov (United States)

    Müller, G C; Junnila, A; Qualls, W; Revay, E E; Kline, D L; Allan, S; Schlein, Y; Xue, R D

    2010-12-01

    Attractive toxic sugar baits (ATSBs) were used to control mosquitoes in the storm drains of a residential area on the outskirts of St Augustine, Florida. The drainage system was newly constructed and no mosquitoes were breeding inside it. The area covered by the storm drains was divided in half; 10 drains served as control drains and 16 drains served as experimental drains. The baits, which consisted of a mixture of brown sugar, fruit juice, green dye marker and boric acid, were presented at the entrances of the treated drains and exit traps were positioned over the drain openings and the connecting tubes leading to retention ponds. Similar baits with orange dye and without toxin were presented at the entrances of control drains. A total of 220 pupae of Culex quinquefasciatus (Diptera: Culicidae) were released in each control and toxin-treated drain, and the numbers of recovered mosquitoes were examined to determine the effectiveness of ATSBs in the storm drain system. An average of 178.2 mosquitoes exited each drain in the control area; 87.0% of these had fed on the baits and were stained orange, whereas 13.0% were unstained. In the toxin-treated drains, 83.7% of hatched females and 86.6% of hatched males were controlled by the baits. © 2010 The Authors. Medical and Veterinary Entomology © 2010 The Royal Entomological Society.

  10. Advanced source/drain and contact design for nanoscale CMOS

    Science.gov (United States)

    Vega, Reinaldo

    The development of nanoscale MOSFETs has given rise to increased attention paid to the role of parasitic source/drain and contact resistance as a performance-limiting factor. Dopant-segregated Schottky (DSS) source/drain MOSFETs have become popular in recent years to address this series resistance issue, since DSS source/drain regions comprise primarily of metal or metal silicide. The small source/drain extension (SDE) regions extending from the metallic contact regions are an important design parameter in DSS MOSFETs, since their size and concentration affect contact resistance, series resistance, band-to-band tunneling (BTBT), SDE tunneling, and direct source-to-drain tunneling (DSDT) leakage. This work investigates key design issues surrounding DSS MOSFETs from both a modeling and experimental perspective, including the effect of SDE design on ambipolar leakage, the effect of random dopant fluctuation (RDF) on specific contact resistivity, 3D FinFET source/drain and contact design optimization, and experimental methods to achieve tuning of the SDE region. It is found that DSS MOSFETs are appropriate for thin body high performance (HP) and low operating power (LOP) MOSFETs, but not low standby power (LSTP) MOSFETs, due to a trade-off between ambipolar leakage and contact resistance. It is also found that DSDT will not limit DSS MOSFET scalability, nor will RDF limit contact resistance scaling, at the end of the CMOS roadmap. Furthermore, it is found that SDE tunability in DSS MOSFETs is achievable in the real-world, for an implant-to-silicide (ITS) process, by employing fluorine implant prior to metal deposition and silicidation. This is found to open up the DSS process design space for the trade-off between SDE junction depth and contact resistance. Si1-xGex process technology is also explored, and Ge melt processing is found to be a promising low-cost alternative to epitaxial Si1-xGex growth for forming crystalline Si1-xGe x films. Finally, a new device

  11. Head Impact Laboratory (HIL)

    Data.gov (United States)

    Federal Laboratory Consortium — The HIL uses testing devices to evaluate vehicle interior energy attenuating (EA) technologies for mitigating head injuries resulting from head impacts during mine/...

  12. Reduction in wick drain effectiveness with spacing for Utah silts and clays.

    Science.gov (United States)

    2012-04-01

    Although decreasing the spacing of vertical drains usually decreases the time for consolidation, previous field tests have shown that there is a critical drain spacing for which tighter spacing does not decrease the time for consolidation. This...

  13. An experimental study on recovering heat from domestic drain water

    Science.gov (United States)

    Ramadan, Mohamad; Al Shaer, Ali; Haddad, Ahmad; Khaled, Mahmoud

    2016-07-01

    This paper concerns an experimental study on a system of heat recovery applied to domestic drain water pipes. The concept suggested consists of using the heat still present in the drain water as a preheating/heating source to the cold water supply of the building. To proceed, an appropriate experimental setup is developed and a coil heat exchanger is used as heat transfer device in the recovery system. Several scenarios are simulated and corresponding parameters are recorded and analyzed. It was shown that the suggested recovery concept can considerably preheat the cold water supply and then decrease the energy consumption. Particularly, up to 8.6 kW of heat were recovered when the cold water supply is initially at 3 °C.

  14. Return Migration After Brain Drain: An Agent Based Simulation Approach

    CERN Document Server

    Biondo, A E; Rapisarda, A

    2012-01-01

    The Brain Drain phenomenon is particularly heterogeneous and is characterized by peculiar specifications. It influences the economic fundamentals of both the country of origin and the host one in terms of human capital accumulation. Here, the brain drain is considered from a microeconomic perspective: more precisely we focus on the individual rational decision to return, referring it to the social capital owned by the worker. The presented model, restricted to the case of academic personnel, compares utility levels to justify agent's migration conduct and to simulate several scenarios with a NetLogo agent based model. In particular, we developed a simulation framework based on two fundamental individual features, i.e. risk aversion and initial expectation, which characterize the dynamics of different agents according to the random evolution of their personal social networks. Our main result is that, according to the value of risk aversion and initial expectation, the probability of return migration depends on...

  15. On the use of drains in orthopedic and trauma

    African Journals Online (AJOL)

    2013-11-08

    Nov 8, 2013 ... On the use of drains in orthopedics and trauma. 367. Nigerian Journal of Clinical Practice • May-Jun 2014 • Vol 17 • Issue 3 may be incurred by the patient, not to mention the distress cause to the patient for another visit to the theatre.[4‑7] In a study of Orthopedic surgeons of the mid‑Trent region of the.

  16. Brain drain or brain gain: The case of Suriname

    OpenAIRE

    Dulam, Tina

    2015-01-01

    markdownabstractAbstract Brain drain refers to the emigration of highly skilled individuals mostly from a less developed (home) to a developed country (destination) thereby reducing the capacity of the home country to generate welfare for its population. In the literature there is much written about this phenomenon, but there is a new theory, entitled brain gain. This theory suggests that the prospect of emigrating and earning higher income when being highly educated encourages the remaining ...

  17. Modeling Draining Flow in Mobile and Immobile Soap Films.

    Science.gov (United States)

    Schwartz; Roy

    1999-10-01

    A mathematical model is constructed to describe the two-dimensional flow in a vertical soap film that is draining under gravity. An asymptotic analysis is employed that uses the long-wave or "lubrication" approximation. The modeling results in three coupled partial differential equations that include a number of dimensionless input parameters. The equations are solved numerically. The three functions calculated, as they vary in space and time, are the film thickness, the surface concentration of an assumed insoluble surfactant, and the slip or surface velocity. The film is assumed to be supported by "wire frame" elements at both the top and the bottom; thus the liquid area and the total surfactant are conserved in the simulation. A two-term "disjoining" pressure is included in the model that allows the development of thin, stable, i.e., "black," films. While the model uses a simplified picture of the relevant physics, it appears to capture observed soap film shape evolution over a large range of surfactant concentrations. The model predicts that, depending on the amount of surfactant that is present, the film profile will pass through several distinct phases. These are (i) rapid initial draining with surfactant transport, (ii) slower draining with an almost immobile interface due to the surface tension gradient effect, and (iii) eventual formation of black spots at various locations on the film. This work is relevant to basic questions concerning surfactant efficacy, as well as to specific questions concerning film and foam draining due to gravity. Prospects for extension to three-dimensional soap film flows are also considered. Copyright 1999 Academic Press.

  18. Methane fluxes from waterlogged and drained Histosols of highland areas

    Directory of Open Access Journals (Sweden)

    Marcos Fernando Glück Rachwal

    2014-04-01

    Full Text Available Soil can be either source or sink of methane (CH4, depending on the balance between methanogenesis and methanotrophy, which are determined by pedological, climatic and management factors. The objective of this study was to assess the impact of drainage of a highland Haplic Histosol on CH4 fluxes. Field research was carried out in Ponta Grossa (Paraná, Brazil based on the measurement of CH4 fluxes by the static chamber method in natural and drained Histosol, over one year (17 sampling events. The natural Histosol showed net CH4 eflux, with rates varying from 238 µg m-2 h-1 CH4, in cool/cold periods, to 2,850 µg m-2 h-1 CH4, in warm/hot periods, resulting a cumulative emission of 116 kg ha-1 yr-1 CH4. In the opposite, the drained Histosol showed net influx of CH4 (-39 to -146 µg m-2 h-1, which resulted in a net consumption of 9 kg ha-1 yr-1 CH4. The main driving factors of CH4 consumption in the drained soil were the lowering of the water-table (on average -57 cm, vs -7 cm in natural soil and the lower water content in the 0-10 cm layer (average of 5.5 kg kg-1, vs 9.9 kg kg-1 in natural soil. Although waterlogged Histosols of highland areas are regarded as CH4 sources, they fulfill fundamental functions in the ecosystem, such as the accumulation of organic carbon (581 Mg ha-1 C to a depth of 1 m and water (8.6 million L ha-1 = 860 mm to a depth of 1 m. For this reason, these soils must not be drained as an alternative to mitigate CH4 emission, but effectively preserved.

  19. Theoretical computation background for transformation of foundations using pile drains

    Directory of Open Access Journals (Sweden)

    Ter-Martirosyan Zaven

    2017-01-01

    Full Text Available In the design of foundations for buildings and structures of various purposes, including improved risk, weak water-saturated clay soils with low mechanical characteristics are often found on a construction site. One of the possible ways of using them as a foundation is to seal them in various ways, including using pile drains of sand or rock stone material that are capable of both absorbing the load at the base and accelerating the process of filtration consolidation. This paper describes an analytical solution to the problem of interaction between the pile and the mattress with the surrounding soil of the foundation, taking into account the possibility of expanding the pile shaft. Solutions are obtained for determining the stresses in the shaft of the pile drain and in the soil under the mattress. The solution takes into account the influence of the pre-stressed state of the foundation after compaction on the formation of a stress-strain state during the erection and operation of structures. The solutions are relevant for consolidating pile drains made of rubble or for jet grouting piles, the rigidity of which is comparable to the rigidity of the surrounding soil. The paper describes the technique for determining the characteristics of the strength and deformability of the converted foundation and the results of large-scale tests at the experimental site for the construction of a large energy facility in Russia.

  20. 7 CFR 58.416 - Cheese vats, tanks and drain tables.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Cheese vats, tanks and drain tables. 58.416 Section 58... Service 1 Equipment and Utensils § 58.416 Cheese vats, tanks and drain tables. (a) The vats, tanks and drain tables used for making cheese should be of metal construction with adequate jacket capacity for...

  1. 14 CFR 25.1455 - Draining of fluids subject to freezing.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Draining of fluids subject to freezing. 25.1455 Section 25.1455 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... § 25.1455 Draining of fluids subject to freezing. If fluids subject to freezing may be drained...

  2. Prediction of Long-Term Drainage-Water Salinity of Pipe Drains

    NARCIS (Netherlands)

    Kelleners, T.J.; Kamra, S.K.; Jhorar, R.K.

    2000-01-01

    Long term drainage water salinity of pipe drains is modeled with the advection-dispersion equation for the zone above drain level and stream functions for the zone below drain level. Steady-state water flow is assumed. The model is applied to two experimental pipe drainage sites in Haryana State,

  3. The Simple Urine Bag as Wound Drain Post-Craniotomy in a Low ...

    African Journals Online (AJOL)

    Background: In the face of the practical non-availability of custom-made surgical wound drain materials, many other substitutes are used in developing countries. ... Data analyzed include the patients' brief demographics; the types of cranial surgery in which drain was used; the drain performance, and any associated ...

  4. Advantage of Plasma Doping for Source/Drain Extension in Bulk Fin Field Effect Transistor

    Science.gov (United States)

    Izumida, Takashi; Okano, Kimitoshi; Kanemura, Takahisa; Kondo, Masaki; Inaba, Satoshi; Itoh, Sanae; Aoki, Nobutoshi; Toyoshima, Yoshiaki

    2011-04-01

    The impact of plasma doping (PD) on the formation of source/drain extension (SDE) is demonstrated for a p-type bulk fin field effect transistor (FinFET). The impurity distribution in a narrow fin (15 nm) was analyzed with atom probe tomography (APT) and secondary ion mass spectroscopy (SIMS). The lateral distribution of boron in the Si fin by the PD is similar to the case with conventional beam-line ion implantation (BL). However, the vertical distribution of boron by the PD is much steeper than that by the conventional BL. TCAD simulations show that the driving current of the FinFET fabricated by the PD is 34% higher than that of the FinFET fabricated by the BL under the same off-leakage current. Therefore, the PD is a key technology for fabricating the SDE of narrow bulk-FinFETs in the future.

  5. Naegleria fowleri from a canal draining cooling water from a factory.

    Science.gov (United States)

    Cerva, L; Jecná, P; Hyhlík, R

    1980-01-01

    In 1968, a canal draining cooling water from a factory was found to be the source of infection with primary amoebic meningoencephalitis (PAME) (one case). The bed of the canal lined with stone slabs was about 2 m wide, the flow rate of water was approximately 2 m/sec. Average annual water temperatures ranged from 27-30 degrees C. In culture, Naegleria fowleri was not found in the water of the canal, but it was present in scrapings off the canal walls and in its bottom sediment for a length of about 2 km starting at the site of the outlet of the water from the factory. The maximum number of amoebae in 1 liter of the sample was 800 individuals. The present paper discusses the detective efficacy of the culture methods employed, and the epidemiological bearing of the findings.

  6. An economic perspective on Malawi's medical "brain drain"

    Directory of Open Access Journals (Sweden)

    Mohiddin Abdu

    2006-12-01

    Full Text Available Abstract Background The medical "brain drain" has been described as rich countries "looting" doctors and nurses from developing countries undermining their health systems and public health. However this "brain-drain" might also be seen as a success in the training and "export" of health professionals and the benefits this provides. This paper illustrates the arguments and possible policy options by focusing on the situation in one of the poorest countries in the world, Malawi. Discussion Many see this "brain drain" of medical staff as wrong with developed countries exploiting poorer ones. The effects are considerable with Malawi facing high vacancy rates in its public health system, and with migration threatening to outstrip training despite efforts to improve pay and conditions. This shortage of staff has made it more challenging for Malawi to deliver on its Essential Health Package and to absorb new international health funding. Yet, without any policy effort Malawi has been able to demonstrate its global competitiveness in the training ("production" of skilled health professionals. Remittances from migration are a large and growing source of foreign exchange for poor countries and tend to go directly to households. Whilst the data for Malawi is limited, studies from other poor countries demonstrate the power of remittances in significantly reducing poverty. Malawi can benefit from the export of health professionals provided there is a resolution of the situation whereby the state pays for training and the benefits are gained by the individual professional working abroad. Solutions include migrating staff paying back training costs, or rich host governments remitting part of a tax (e.g. income or national insurance to the Malawi government. These schemes would allow Malawi to scale up training of health professionals for local needs and to work abroad. Summary There is concern about the negative impacts of the medical "brain-drain". However a

  7. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... News Physician Resources Professions Site Index A-Z Computed Tomography (CT) - Head Computed tomography (CT) of the head uses special x-ray ... Head? What is CT Scanning of the Head? Computed tomography, more commonly known as a CT or CAT ...

  8. Imaging of accidental paediatric head trauma

    Energy Technology Data Exchange (ETDEWEB)

    Tang, Phua Hwee [KK Women' s and Children' s Hospital, Department of Diagnostic Imaging, Singapore (Singapore); Lim, Choie Cheio Tchoyoson [National Neuroscience Institute, Department of Neuroradiology, Singapore (Singapore)

    2009-05-15

    Head trauma is the most common form of injury sustained in serious childhood trauma and remains one of the top three causes of death despite improved road planning and safety laws. CT remains the first-line investigation for paediatric head trauma, although MRI may be more sensitive at picking up the full extent of injuries and may be useful for prognosis. Follow-up imaging should be tailored to answer the specific clinical question and to look for possible complications. (orig.)

  9. A retrospective study of the use of active suction wound drains in dogs and cats.

    Science.gov (United States)

    Bristow, P C; Halfacree, Z J; Baines, S J

    2015-05-01

    To report indications for use and complications associated with commonly used closed active suction wound drains in a large number of clinical cases. Retrospective review of medical case records (from 2004 to 2010) for dogs and cats that had a closed active suction drain placed into a wound. Only the four most common drain types were included: Mini Redovac®, Redovac®, Jackson Pratt® and Wound Evac®. Two hundred and fifty-three drains were placed in 33 cats and 195 dogs. Mini Redovac drains were used most frequently in cats (76 · 5%) and Redovac drains in dogs (54 · 3%). The infection rate for clean surgeries in dogs was 15 · 6% (unattainable in cats). Major complications occurred in four dogs; minor complications occurred in 12 drains in cats (35 · 3%), and in 74 drains in dogs (33 · 8%). There was no statistically significant association between the type of drain and complication rate for either species. Although closed active suction drains can be used with low risk of major complications, they lead to a high rate of infection in clean surgeries in dogs. It is recommended that such drains are kept in place for the shortest time possible and that strict asepsis is adhered to both during placement and management. © 2015 British Small Animal Veterinary Association.

  10. Drain current local variability from linear to saturation region in 28 nm bulk NMOSFETs

    Science.gov (United States)

    Karatsori, T. A.; Theodorou, C. G.; Haendler, S.; Dimitriadis, C. A.; Ghibaudo, G.

    2017-02-01

    In this work, we investigate the impact of the source - drain series resistance mismatch on the drain current variability in 28 nm bulk MOSFETs. For the first time, a mismatch model including the local fluctuations of the threshold voltage (Vt), the drain current gain factor (β) and the source - drain series resistance (RSD) in both linear and saturation regions is presented. Furthermore, it is demonstrated that the influence of the source - drain series resistance mismatch is attenuated in the saturation region, due to the weaker sensitivity of the drain current variability on the series resistance variation. The experimental results were further verified by numerical simulations of the drain current characteristics with sensitivity analysis of the MOSFET parameters Vt, β and RSD.

  11. Is a closed-suction drain advantageous for penile implant surgery? The debate continues.

    Science.gov (United States)

    Kramer, Andrew; Goldmark, Ellen; Greenfield, Jason

    2011-02-01

    The debate about leaving a closed-suction drain during penile implant surgery remains unsolved. What is the current thinking about the pros and cons of leaving a scrotal drain for inflatable penile implant (IPP) surgery? The aim of this study is to explore the fund of existing information, and formulate a point and counterpoint debate analyzing the drain issue for implant surgery. Two differing points of view are given to answer the question of benefit vs. risk drains in implant patients. To facilitate the debate about a longstanding urologic question. There are two conflicting points presented in this manuscript, one supporting drain placement, the other opposing it in light of the risks and benefits. Without prospective randomized controlled trials specifically looking at drain placement following IPP, it is unclear whether or not this intervention is beneficial. Until a study of this type is performed, leaving a drain will largely remain a surgeon preference. © 2010 International Society for Sexual Medicine.

  12. India: 'brain drain' or the migration of talent?

    Science.gov (United States)

    Oommen, T K

    1989-09-01

    2 views on "brain drain" exist: 1) LDCs lose their enormous investments on higher education when skilled people migrate to other countries and 2) LDCs are exaggerating the problem and only a few skilled people migrate at 1 time. India does not completely lose its investment in education when professionals migrate, since the migrants still contribute to knowledge and also send remittances to relatives in India. Unemployed educated people would cause a greater drain on India's resources than educated migrants. The author prefers the phrase migration of talent to brain drain, since the former indicates a 2-way movement. Most migrants from LDCs are students. About 11,000 university graduates leave India every year for advanced study and/or work. A conservative estimate is that 2500 will remain abroad permanently. Most professionals who migrate go to the US and Canada. Factors promoting migration include 1) unemployment, 2) immigration rules, 3) colonial links, 4) financial incentives and material benefits, 5) pursuit of higher education, 6) improvement of working conditions and facilities, 7) avoidance of excessive bureaucratic procedures, and 8) compensation for the mismatch between Indian education and employment. Reasons for returning to India include 1) deference to wives who were unable to adjust to a foreign way of life, 2) contributing to Indian development, and 3) racial discrimination. It will probably not be possible to lure back migrants who left for material reasons. Attractive job offers could entice back those who left for advanced training. To encourage the return of those who left to pursue high quality research, India must 1) increase expenditure on research and development, possibly through the private industrial sector, 2) promote travel to other countries for professional enrichment, and 3) improve conditions of research work. The article concludes with an analysis of migration of talent from 3 perspectives: 1) the individual, 2) the nation

  13. Randomized trial of drain antisepsis after mastectomy and immediate prosthetic breast reconstruction.

    Science.gov (United States)

    Degnim, Amy C; Hoskin, Tanya L; Brahmbhatt, Rushin D; Warren-Peled, Anne; Loprinzi, Margie; Pavey, Emily S; Boughey, Judy C; Hieken, Tina J; Jacobson, Steven; Lemaine, Valerie; Jakub, James W; Irwin, Chetan; Foster, Robert D; Sbitany, Hani; Saint-Cyr, Michel; Duralde, Erin; Ramaker, Sheri; Chin, Robin; Sieg, Monica; Wildeman, Melissa; Scow, Jeffrey S; Patel, Robin; Ballman, Karla; Baddour, Larry M; Esserman, Laura J

    2014-10-01

    In this 2-site randomized trial, we investigated the effect of antiseptic drain care on bacterial colonization of surgical drains and infection after immediate prosthetic breast reconstruction. With IRB approval, we randomized patients undergoing bilateral mastectomy and reconstruction to drain antisepsis (treatment) for one side, with standard drain care (control) for the other. Antisepsis care included both: chlorhexidine disc dressing at drain exit site(s) and irrigation of drain bulbs twice daily with dilute sodium hypochlorite solution. Cultures were obtained from bulb fluid at 1 week and at drain removal, and from the subcutaneous drain tubing at removal. Positive cultures were defined as ≥1+ growth for fluid and >50 CFU for tubing. Cultures of drain bulb fluid at 1 week (the primary endpoint) were positive in 9.9 % of treatment sides (10 of 101) versus 20.8 % (21 of 101) of control sides (p = 0.02). Drain tubing cultures were positive in 0 treated drains versus 6.2 % (6 of 97) of control drains (p = 0.03). Surgical site infection occurred within 30 days in 0 antisepsis sides versus 3.8 % (4 of 104) of control sides (p = 0.13), and within 1 year in three of 104 (2.9 %) of antisepsis sides versus 6 of 104 (5.8 %) of control sides (p = 0.45). Clinical infection occurred within 1 year in 9.7 % (6 of 62) of colonized sides (tubing or fluid) versus 1.5 % (2 of 136) of noncolonized sides (p = 0.03). Simple and inexpensive local antiseptic interventions with a chlorhexidine disc and hypochlorite solution reduce bacterial colonization of drains, and reduced drain colonization was associated with fewer infections.

  14. Primum Nocere: Medical Brain Drain and the Duty to Stay.

    Science.gov (United States)

    Ferracioli, Luara; De Lora, Pablo

    2015-10-01

    In this essay, we focus on the moral justification of a highly controversial measure to redress medical brain drain: the duty to stay. We argue that the moral justification for this duty lies primarily in the fact that medical students impose high risks on their fellow citizens while receiving their medical training, which in turn gives them a reciprocity-based reason to temporarily prioritize the medical needs of their fellow citizens. © The Author 2015. Published by Oxford University Press, on behalf of the Journal of Medicine and Philosophy Inc. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  15. Brain-drain and health care delivery in developing countries.

    Science.gov (United States)

    Misau, Yusuf Abdu; Al-Sadat, Nabilla; Gerei, Adamu Bakari

    2010-09-01

    Migration of health workers 'Brain drain' is defined as the movement of health personnel in search of a better standard of living and life quality, higher salaries, access to advanced technology and more stable political conditions in different places worldwide. The debate about migration of health workers from the developing to the developed world has remained pertinent for decades now. Regardless of the push and pull factors, migration of health care workers from developing countries to developed ones, have done more harm than good on the health care deliveries in the developing countries. This article reviews the literature on the effects of cross-border migration of health care professionals.

  16. Right superior vena cava draining into the left atrium

    Energy Technology Data Exchange (ETDEWEB)

    Calcagni, Giulio; Sidi, Daniel; Bonnet, Damien [University Rene Descartes-Paris 5, Department of Paediatric Cardiology, Hopital Necker-Enfants Malades, Paris (France); Batisse, Alain [Institut de Puericulture et de Perinatalogie, Paris (France); Vouhe, Pascal [University Rene Descartes-Paris 5, Department of Paediatric Cardiac Surgery, Hopital Necker-Enfants Malades, Paris (France); Ou, Phalla [University Rene Descartes-Paris 5, Department of Paediatric Cardiology, Hopital Necker-Enfants Malades, Paris (France); University Rene Descartes-Paris 5, Department of Pediatric Radiology, Hopital Necker-Enfants Malades, Paris (France)

    2008-08-15

    The right superior vena cava draining into the left atrium is a rare malformation causing cyanosis and clubbing in patients in whom no other signs of congenital heart defect are present. Diagnosis may be difficult as cyanosis may be mild and the anomaly is not always easily detectable by echocardiography. For this reason we report a 13-month-old male in whom we confirmed the clinical and echocardiographic suspicion of anomalous drainage of the right superior vena cava using multidetector CT. This allowed successful surgical reconnection of the right superior vena cava to the right atrium. (orig.)

  17. Application of Prefabricated Vertical Drain in Soil Improvement

    Directory of Open Access Journals (Sweden)

    Tedjakusuma B.

    2012-01-01

    Full Text Available Although the use of Prefabricated Vertical Drain (PVD in soil improvement is not new, this paper is interesting since it gives the full spectrum from preliminary design stage; trial embankment and pilot test to final soil improvement. The final installation of the PVD was based on the soil investigation report and the results of instrumentation monitoring. Finally, using back analysis, vertical and horizontal coefficients of consolidation and compression index can be determined, which can be applied to predict a more accurate prediction of settlement.

  18. Fat Harvest Using a Closed-Suction Drain

    Directory of Open Access Journals (Sweden)

    Kavit Amin

    2016-05-01

    Full Text Available We propose a safe, simple, and novel method to harvest fat using a standard liposuction cannula and a Redivac or alternative closed-suction drain. The authors have used this technique for both 'dry' and 'wet' liposuction. This technique is both easy to perform and cost-effective whilst providing both a silent and relatively atraumatic fat harvest. The lower negative pressure compared with traditional harvesting systems likely preserves fat integrity for lipofilling. This method maximises resources already held within a hospital environment.

  19. Responses of Young Slash Pine on Poorly Drained to Somewhat Poorly Drained Silt Loam Soils to Site Preparation and Fertilization Treatments

    Science.gov (United States)

    James D. Haywood

    1995-01-01

    Slash pines (Pinus elliottii Engelm. var. elliottii) were planted on poorly drained Wrightsville and somewhat poorly drained Vidrine silt loam soils in southwest Louisiana. Neither flat disking nor bedding increased pine growth and yield substantially after nine growing seasons, but broadcast application of triple superphoshate...

  20. Irradiation-induced regulation of plasminogen activator inhibitor type-1 and vascular endothelial growth factor in six human squamous cell carcinoma lines of the head and neck; Bestrahlungsinduzierte Regulation des Plasminogenaktivator-Inhibitor Typ 1 (PAI-1) und des vaskulaeren endothelialen Wachstumsfaktors (VEGF) in sechs Plattenepithelkarzinomzelllinien der Kopf-Hals-Region

    Energy Technology Data Exchange (ETDEWEB)

    Artman, Meri Tuuli

    2014-01-29

    Radiation therapy is frequently used to treat squamous cell carcinoma of the head and neck (SCCHN), although, it can be unsuccessful due to radiation resistance of the tumor. Currently, there are no established predictive markers for radiation resistance in SCCHN. The aim of this work was to investigate PAI-1 and VEGF secretion as markers for radiation resistance in six human SCCHN cell lines. The cell lines differed in their basal secretion levels and in their in vitro radiation sensitivity. PAI-1 and VEGF levels increased after irradiation in a dose-dependent manner. A significant correlation was detected between radiation-induced PAI-1 and VEGF secretion, which suggests that irradiation-induced secretion of PAI-1 and VEGF are partially regulated by related mechanisms. However, neither basal levels nor radiation-induced PAI-1 and VEGF secretion correlated with radiation resistance. Therefore, PAI-1 and VEGF are most likely not predictive markers for radiation resistance in SCCHN.

  1. English and the Brain Drain: an Uncertain Relationship

    Directory of Open Access Journals (Sweden)

    Houtkamp Christopher

    2016-10-01

    Full Text Available In his book Linguistic Justice for Europe and the World, Van Parijs analyses in one of his chapters the brain drain from non-Anglophone to Anglophone countries, which hurts the economic development of the non-Anglophone states. Van Parijs deems it clear that English is a very important factor to explain high-skilled migration. He, therefore, urges the non-Anglophone countries to relax their linguistic territorial constraints and allow English as a communication language in many different sectors, most notably higher education and scientific research. This would remove the incentive for potential expatriate brains to migrate for linguistic reasons. This article takes a closer look at Van Parijs’ reasoning and proposed solutions. It is concluded that the assumed connection between English and high-skilled migration cannot be proven empirically for research on this topic is scarcely available. Furthermore, the solutions presented by Van Parijs will produce uncertain results at best. Van Parijs rightfully puts the brain drain problem on the political and research agenda, but much more additional studies are needed to formulate solid solutions.

  2. Consolidation by Prefabricated Vertical Drains with a Threshold Gradient

    Directory of Open Access Journals (Sweden)

    Xiao Guo

    2014-01-01

    Full Text Available This paper shows the development of an approximate analytical solution of radial consolidation by prefabricated vertical drains with a threshold gradient. To understand the effect of the threshold gradient on consolidation, a parametric analysis was performed using the present solution. The applicability of the present solution was demonstrated in two cases, wherein the comparisons with Hansbo’s results and observed data were conducted. It was found that (1 the flow with the threshold gradient would not occur instantaneously throughout the whole unit cell. Rather, it gradually occurs from the vertical drain to the outside; (2 the moving boundary would never reach the outer radius of influence if R+1

  3. Head injury - first aid

    Science.gov (United States)

    ... medlineplus.gov/ency/article/000028.htm Head injury - first aid To use the sharing features on this page, ... a concussion can range from mild to severe. First Aid Learning to recognize a serious head injury and ...

  4. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... the head is typically used to detect: bleeding, brain injury and skull fractures in patients with head injuries. ... hard time staying still, are claustrophobic or have chronic pain, you may find a CT exam to ...

  5. Head and face reconstruction

    Science.gov (United States)

    ... medlineplus.gov/ency/article/002980.htm Head and face reconstruction To use the sharing features on this page, please enable JavaScript. Head and face reconstruction is surgery to repair or reshape deformities ...

  6. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... the limitations of CT Scanning of the Head? What is CT Scanning of the Head? Computed tomography, ... than regular radiographs (x-rays). top of page What are some common uses of the procedure? CT ...

  7. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... for Brain Tumors Radiation Therapy for Head and Neck Cancer Others American Stroke Association National Stroke Association ... Computer Tomography (CT) Safety During Pregnancy Head and Neck Cancer X-ray, Interventional Radiology and Nuclear Medicine ...

  8. Newborn head molding

    Science.gov (United States)

    Newborn cranial deformation; Molding of the newborn's head; Neonatal care - head molding ... The bones of a newborn baby's skull are soft and flexible, with gaps between the plates of bone. The spaces between the bony plates of ...

  9. Drain Insertion in Chronic Subdural Hematoma: An International Survey of Practice.

    Science.gov (United States)

    Soleman, Jehuda; Kamenova, Maria; Lutz, Katharina; Guzman, Raphael; Fandino, Javier; Mariani, Luigi

    2017-08-01

    To investigate whether, after the publication of grade I evidence that it reduces recurrence rates, the practice of drain insertion after burr-hole drainage of chronic subdural hematoma has changed. Further, we aimed to document various practice modalities concerning the insertion of a drain adopted by neurosurgeons internationally. We administered a survey to neurosurgeons worldwide with questions relating to the surgical treatment of chronic subdural hematoma, with an emphasis on their practices concerning the use of a drain. The preferred surgical technique was burr-hole drainage (89%). Most surgeons prefer to place a drain (80%), whereas in 56% of the cases the reason for not placing a drain was brain expansion after evacuation. Subdural drains are placed by 50% and subperiosteal drains by 27% of the responders, whereas 23% place primarily a subdural drain if possible and otherwise a subperiosteal drain. Three quarters of the responders leave the drain for 48 hours and give prophylactic antibiotic treatment, mostly a single-shot dose intraoperatively (70%). Routine postoperative computed tomography is done by 59% mostly within 24-48 hours after surgery (94%). Adjunct treatment to surgery rarely is used (4%). The publication of grade I evidence in favor of drain use influenced positively this practice worldwide. Some surgeons are still reluctant to insert a drain, especially when the subdural space is narrow after drainage of the hematoma. The insertion of a subperiosteal drain could be a good alternative solution. However, its outcome and efficacy must be evaluated in larger studies. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Estimating drain flow from measured water table depth in layered soils under free and controlled drainage

    Science.gov (United States)

    Saadat, Samaneh; Bowling, Laura; Frankenberger, Jane; Kladivko, Eileen

    2018-01-01

    Long records of continuous drain flow are important for quantifying annual and seasonal changes in the subsurface drainage flow from drained agricultural land. Missing data due to equipment malfunction and other challenges have limited conclusions that can be made about annual flow and thus nutrient loads from field studies, including assessments of the effect of controlled drainage. Water table depth data may be available during gaps in flow data, providing a basis for filling missing drain flow data; therefore, the overall goal of this study was to examine the potential to estimate drain flow using water table observations. The objectives were to evaluate how the shape of the relationship between drain flow and water table height above drain varies depending on the soil hydraulic conductivity profile, to quantify how well the Hooghoudt equation represented the water table-drain flow relationship in five years of measured data at the Davis Purdue Agricultural Center (DPAC), and to determine the impact of controlled drainage on drain flow using the filled dataset. The shape of the drain flow-water table height relationship was found to depend on the selected hydraulic conductivity profile. Estimated drain flow using the Hooghoudt equation with measured water table height for both free draining and controlled periods compared well to observed flow with Nash-Sutcliffe Efficiency values above 0.7 and 0.8 for calibration and validation periods, respectively. Using this method, together with linear regression for the remaining gaps, a long-term drain flow record for a controlled drainage experiment at the DPAC was used to evaluate the impacts of controlled drainage on drain flow. In the controlled drainage sites, annual flow was 14-49% lower than free drainage.

  11. Head impact exposure in collegiate football players.

    Science.gov (United States)

    Crisco, Joseph J; Wilcox, Bethany J; Beckwith, Jonathan G; Chu, Jeffrey J; Duhaime, Ann-Christine; Rowson, Steven; Duma, Stefan M; Maerlender, Arthur C; McAllister, Thomas W; Greenwald, Richard M

    2011-10-13

    In American football, impacts to the helmet and the resulting head accelerations are the primary cause of concussion injury and potentially chronic brain injury. The purpose of this study was to quantify exposures to impacts to the head (frequency, location and magnitude) for individual collegiate football players and to investigate differences in head impact exposure by player position. A total of 314 players were enrolled at three institutions and 286,636 head impacts were recorded over three seasons. The 95th percentile peak linear and rotational acceleration and HITsp (a composite severity measure) were 62.7g, 4378rad/s(2) and 32.6, respectively. These exposure measures as well as the frequency of impacts varied significantly by player position and by helmet impact location. Running backs (RB) and quarter backs (QB) received the greatest magnitude head impacts, while defensive line (DL), offensive line (OL) and line backers (LB) received the most frequent head impacts (more than twice as many than any other position). Impacts to the top of the helmet had the lowest peak rotational acceleration (2387rad/s(2)), but the greatest peak linear acceleration (72.4g), and were the least frequent of all locations (13.7%) among all positions. OL and QB had the highest (49.2%) and the lowest (23.7%) frequency, respectively, of front impacts. QB received the greatest magnitude (70.8g and 5428rad/s(2)) and the most frequent (44% and 38.9%) impacts to the back of the helmet. This study quantified head impact exposure in collegiate football, providing data that is critical to advancing the understanding of the biomechanics of concussive injuries and sub-concussive head impacts. Copyright © 2011 Elsevier Ltd. All rights reserved.

  12. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... limitations of CT Scanning of the Head? What is CT Scanning of the Head? Computed tomography, more commonly known as a ... top of page What are some common uses of the procedure? CT scanning of the head is ...

  13. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... Computed tomography (CT) of the head uses special x-ray equipment to help assess head injuries, severe headaches, dizziness, and other symptoms of ... content. Related Articles and Media Radiation Dose in X-Ray and CT ... Perfusion of the Head CT Angiography (CTA) Stroke Brain Tumors Computer Tomography ( ...

  14. Brain drain and health workforce distortions in Mozambique.

    Directory of Open Access Journals (Sweden)

    Kenneth Sherr

    Full Text Available Trained human resources are fundamental for well-functioning health systems, and the lack of health workers undermines public sector capacity to meet population health needs. While external brain drain from low and middle-income countries is well described, there is little understanding of the degree of internal brain drain, and how increases in health sector funding through global health initiatives may contribute to the outflow of health workers from the public sector to donor agencies, non-governmental organisations (NGOs, and the private sector.An observational study was conducted to estimate the degree of internal and external brain drain among Mozambican nationals qualifying from domestic and foreign medical schools between 1980-2006. Data were collected 26-months apart in 2008 and 2010, and included current employment status, employer, geographic location of employment, and main work duties.Of 723 qualifying physicians between 1980-2006, 95.9% (693 were working full-time, including 71.1% (493 as clinicians, 20.5% (142 as health system managers, and 6.9% (48 as researchers/professors. 25.5% (181 of the sample had left the public sector, of which 62.4% (113 continued working in-country and 37.6% (68 emigrated from Mozambique. Of those cases of internal migration, 66.4% (75 worked for NGOs, 21.2% (24 for donor agencies, and 12.4% (14 in the private sector. Annual incidence of physician migration was estimated to be 3.7%, predominately to work in the growing NGO sector. An estimated 36.3% (41/113 of internal migration cases had previously held senior-level management positions in the public sector.Internal migration is an important contributor to capital flight from the public sector, accounting for more cases of physician loss than external migration in Mozambique. Given the urgent need to strengthen public sector health systems, frank reflection by donors and NGOs is needed to assess how hiring practices may undermine the very systems they

  15. Greenhouse gases emission from the sewage draining rivers.

    Science.gov (United States)

    Hu, Beibei; Wang, Dongqi; Zhou, Jun; Meng, Weiqing; Li, Chongwei; Sun, Zongbin; Guo, Xin; Wang, Zhongliang

    2018-01-15

    Carbon dioxide (CO2), methane (CH4) and nitrous oxide (N2O) concentration, saturation and fluxes in rivers (Beitang drainage river, Dagu drainage rive, Duliujianhe river, Yongdingxinhe river and Nanyunhe river) of Tianjin city (Haihe watershed) were investigated during July and October in 2014, and January and April in 2015 by static headspace gas chromatography method and the two-layer model of diffusive gas exchange. The influence of environmental variables on greenhouse gases (GHGs) concentration under the disturbance of anthropogenic activities was discussed by Spearman correlative analysis and multiple stepwise regression analysis. The results showed that the concentration and fluxes of CO2, CH4 and N2O were seasonally variable with >winter>fall>summer, spring>summer>winter>fall and summer>spring>winter>fall for concentrations and spring>summer>fall>winter, spring>summer>winter>fall and summer>spring>fall>winter for fluxes respectively. The GHGs concentration and saturation were higher in comprehensively polluted river sites and lower in lightly polluted river sites. The three GHGs emission fluxes in two sewage draining rivers of Tianjin were clearly higher than those of other rivers (natural rivers) and the spatial variation of CH4 was more obvious than the others. CO2 and N2O air-water interface emission fluxes of the sewage draining rivers in four seasons were about 1.20-2.41 times and 1.13-3.12 times of those in the natural rivers. The CH4 emission fluxes of the sewage draining rivers were 3.09 times in fall to 10.87 times in spring of those in the natural rivers in different season. The wind speed, water temperature and air temperature were related to GHGs concentrations. Nitrate and nitrite (NO3-+NO2--N) and ammonia (NH4+-N) were positively correlated with CO2 concentration and CH4 concentration; and dissolved oxygen (DO) concentration was negatively correlated with CH4 concentration and N2O concentration. The effect of human activities on carbon and

  16. RF power FinFET transistors with a wide drain-extended fin

    Science.gov (United States)

    Chen, Bo-Yuan; Chen, Kun-Ming; Chiu, Chia-Sung; Huang, Guo-Wei; Chen, Hsiu-Chih; Chen, Chun-Chi; Hsueh, Fu-Kuo; Chen, Min-Cheng; Chang, Edward Yi

    2017-04-01

    Drain-extended FinFET transistors for RF power applications have been fabricated and is presented in this paper. Power FinFETs with a wide drain extension are proposed to reduce the drain resistance. Compared with conventional drain-extended FinFETs, our proposed new devices exhibit lower on-resistances and better high-frequency performances while keeping a similar breakdown voltage. The enhancements of the on-resistance and peak cutoff frequency are 16 and 56%, respectively, under an optimal drain-extension layout. These experimental results suggest that FinFET transistors with a wide drain extension could be used for RF power applications, increasing the possibility of integrating RF power parts into future FinFET system-on-a-chip technologies.

  17. The Effect of Coriolis Force on the Formation of Dip on the Free Surface of Water Draining from a Tank

    Energy Technology Data Exchange (ETDEWEB)

    Jo, Jong Chull; Kang, Dong Gu; Kim, Hho Jhung; Roh, Kyung Wan; Yune, Young Gill [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2007-10-15

    For the case of RWT (refueling water tank) connecting to the ECC (emergency core cooling) line, it can be surmised that there is a possibility of ECC pump failure due to air ingression into the ECC supply line even before the RWT is drained away. Therefore, it is important to check if the operational limit of the RWT water level is set at a value higher than the critical height that causes a dip formation on the free surface of a draining liquid. In the previous work, such complex unsteady flow fields both in a simple water tank and in the RWT at the Korean standard nuclear power plant have been simulated using the CFX5.10 code which is well-known as one of the well-validated commercial CFD (Computational Fluid Dynamics) codes. However, for the simplicity of those calculations the Coriolis force has not been taken into account. Thus, in the present paper, the effect of Coriolis force-induced vortex flow on the dip formation of dip has been investigated for the simple water tank to confirm validity of the previous work. To do this the unsteady flow fields accompanied by vortex in the simple water tank has been simulated using the CFX5.10 code.

  18. The Requirement of Sutures to Close Intercostal Drains Site Wounds in Thoracic Surgery.

    Science.gov (United States)

    Smelt, Jeremy L C; Simon, Natalie; Veres, Lukacs; Harrison-Phipps, Karen; Bille, Andrea

    2018-02-01

    Chest drains are used routinely in thoracic surgery. Often a pursestring or mattress suture is used to facilitate closure of the defect on removal of the drain. This stitch can cause an unsightly scar, increase drain removal pain, and necessitate that the patient attend a community health care center to have this removed. The objective of this study was to assess whether this stitch is necessary in modern thoracic surgical practice. Data from a single surgeon's practice were collected over an 18-month period. During this time, all patients who underwent both emergency and elective thoracic surgery who had at least one postoperative chest drain of 28F or above inserted were included in the study. The surgeon did not routinely use a suture to close the drain site. In all, 312 patients underwent thoracic surgery during the 18-month period. Each patient had a range of 1 to 3 drains inserted of a size between 28F and 32F. No patients had drain sutures for closure of the drain site. Four patients had pneumothoraces after drain removal requiring further chest drain insertion. Five patients had superficial drain site infections. A single patient had to have a suture inserted at a local hospital owing to leakage from the drain site. The use of pursestring sutures in thoracic surgery is an outdated practice that causes not only unsightly scars but is also associated with increased pain. Furthermore, these unnecessary pursestring sutures place a burden on the patient and health care system to have them removed. Copyright © 2018 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  19. Effect of an intervention in storm drains to prevent Aedes aegypti reproduction in Salvador, Brazil

    OpenAIRE

    Souza, Raquel Lima; Mugabe, V?nio Andr?; Paploski,Igor Adolfo Dexheimer; Rodrigues, Moreno S.; Moreira, Patr?cia Sousa dos Santos; Nascimento, Leile Camila Jacob; Roundy, Christopher Michael; Weaver, Scott C.; Reis, Mitermayer Galv?o; Kitron, Uriel; Ribeiro,Guilherme Sousa

    2017-01-01

    Background Aedes aegypti, the principal vector for dengue, chikungunya and Zika viruses, is a synanthropic species that uses stagnant water to complete its reproductive cycle. In urban settings, rainfall water draining structures, such as storm drains, may retain water and serve as a larval development site for Aedes spp. reproduction. Herein, we describe the effect of a community-based intervention on preventing standing water accumulation in storm drains and their consequent infestation by ...

  20. Effect of an intervention in storm drains to prevent Aedes aegypti reproduction in Salvador, Brazil.

    Science.gov (United States)

    Souza, Raquel Lima; Mugabe, Vánio André; Paploski, Igor Adolfo Dexheimer; Rodrigues, Moreno S; Moreira, Patrícia Sousa Dos Santos; Nascimento, Leile Camila Jacob; Roundy, Christopher Michael; Weaver, Scott C; Reis, Mitermayer Galvão; Kitron, Uriel; Ribeiro, Guilherme Sousa

    2017-07-11

    Aedes aegypti, the principal vector for dengue, chikungunya and Zika viruses, is a synanthropic species that uses stagnant water to complete its reproductive cycle. In urban settings, rainfall water draining structures, such as storm drains, may retain water and serve as a larval development site for Aedes spp. reproduction. Herein, we describe the effect of a community-based intervention on preventing standing water accumulation in storm drains and their consequent infestation by adult and immature Ae. aegypti and other mosquitoes. Between April and May of 2016, local residents association of Salvador, Brazil, after being informed of water accumulation and Ae. aegypti infestation in the storm drains in their area, performed an intervention on 52 storm drains. The intervention consisted of placing concrete at the bottom of the storm drains to elevate their base to the level of the outflow tube, avoiding water accumulation, and placement of a metal mesh covering the outflow tube to avoid its clogging with debris. To determine the impact of the intervention, we compared the frequency at which the 52 storm drains contained water, as well as adult and immature mosquitoes using data from two surveys performed before and two surveys performed after the intervention. During the pre-intervention period, water accumulated in 48 (92.3%) of the storm drains, and immature Ae. aegypti were found in 11 (21.2%) and adults in 10 (19.2%). After the intervention, water accumulated in 5 (9.6%) of the storm drains (P storm drains also decreased after the intervention. This study exemplifies how a simple intervention targeting storm drains can result in a major reduction of water retention, and, consequently, impact Ae. aegypti larval populations. Larger and multi-center evaluations are needed to confirm the potential of citywide structural modifications of storm drains to reduce Aedes spp. infestation level.

  1. Magnetic Resonance Imaging (MRI) -- Head

    Science.gov (United States)

    ... News Physician Resources Professions Site Index A-Z Magnetic Resonance Imaging (MRI) - Head Magnetic resonance imaging (MRI) of the head ... limitations of MRI of the Head? What is MRI of the Head? Magnetic resonance imaging (MRI) is ...

  2. Revisited approach for the characterization of Gate Induced Drain Leakage

    Science.gov (United States)

    Rafhay, Quentin; Xu, Cuiqin; Batude, Perrine; Mouis, Mireille; Vinet, Maud; Ghibaudo, Gérard

    2012-05-01

    This work presents a critical review and a re-investigation of the electrical characterization of Gate Induced Drain Leakage (GIDL) [1,2]. The underlying assumptions of the previously proposed extraction methods are exposed and their ability to capture Band-to-Trap mechanisms is discussed. A new approach is introduced to overcome some of the limiting assumptions made by the previous extraction methods. This new approach is benchmarked against the previously proposed ones. The results show that it enables a better extraction of the GIDL parameters compared to the conventional methods, by using the voltage dependency of the activation energy to gain insight in the electric field responsible for Band-to-Band Tunneling in the device. Finally, the experimental application of this new approach is carried out on cold process FDSOI MOSFET and confirms the ability of this new method to quantify the impact of trap assisted tunneling on GIDL.

  3. Differential radiodiagnosis of draining pararectal cysts and rectal fistulas

    Energy Technology Data Exchange (ETDEWEB)

    Mushnikova, V.N.; Savvateeva, N.Yu.; Arablinskij, V.M.

    Proceeding from an analysis of multimodality examination and treatment of patients with difficulties in differential diagnosis, it has been established that proctography and fistulography play the most important role in radiodiagnosis. The presence of a multichamber cavity with clear even contours at the level of the medium- or lower ampullar region of the rectum is characteristic of draining pararectal cysts. The fustulous passage is single and unramified. Usually there is no connection between the cavity and fistula with the rectum. In rectal fistulas as a result of chronic periproctites the cavity is single, of uneven shape with unclear irregular contours at the level of the anal canal or lower ampullar region of the rectum. The fustulous passage is ramified, frequently connected with the rectal lumen.

  4. Wettable Ceramic-Based Drained Cathode Technology for Aluminum Electrolysis

    Energy Technology Data Exchange (ETDEWEB)

    J.N. Bruggeman; T.R. Alcorn; R. Jeltsch; T. Mroz

    2003-01-09

    The goal of the project was to develop the ceramic based materials, technology, and necessary engineering packages to retrofit existing aluminum reduction cells in order to reduce energy consumption required for making primary aluminum. The ceramic materials would be used in a drained cathode configuration which would provide a stable, molten aluminum wetted cathode surface, allowing the reduction of the anode-cathode distance, thereby reducing the energy consumption. This multi-tasked project was divided into three major tasks: (1) Manufacturing and laboratory scale testing/evaluation of the ceramic materials, (2) Pilot scale testing of qualified compositions from the first task, and (3) Designing, retrofitting, and testing the ceramic materials in industrial cells at Kaiser Mead plant in Spokane, Washington. Specific description of these major tasks can be found in Appendix A - Project Scope. Due to the power situation in the northwest, the Mead facility was closed, thus preventing the industrial cell testing.

  5. How Do Meningeal Lymphatic Vessels Drain the CNS?

    Science.gov (United States)

    Raper, Daniel; Louveau, Antoine; Kipnis, Jonathan

    2016-09-01

    The many interactions between the nervous and the immune systems, which are active in both physiological and pathological states, have recently become more clearly delineated with the discovery of a meningeal lymphatic system capable of carrying fluid, immune cells, and macromolecules from the central nervous system (CNS) to the draining deep cervical lymph nodes. However, the exact localization of the meningeal lymphatic vasculature and the path of drainage from the cerebrospinal fluid (CSF) to the lymphatics remain poorly understood. Here, we discuss the potential differences between peripheral and CNS lymphatic vessels and examine the purported mechanisms of CNS lymphatic drainage, along with how these may fit into established patterns of CSF flow. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. Centrifuge modelling of drained lateral pile - soil response

    DEFF Research Database (Denmark)

    Klinkvort, Rasmus Tofte

    popular foundation methods today for offshore wind turbines. These piles are often installed in dense sand at water depths ranging from 10-30 meters. A monopile is a single, large diameter tubular steel pile. The current design methodology originates from tests on long slender piles but is also used...... for monopiles today. Therefore it appears that the methodology for monopiles lacks scientific justification and a better understanding of rigid piles is needed. More than 70 centrifuge tests on laterally loaded rigid model piles have been carried out in connection with this thesis to get a better understanding...... of rigid piles. The tests have been performed in homogeneously dense dry or saturated Fontainebleau sand in order to mimic simplified drained offshore soil conditions. Approximately half of the tests have been carried out to investigate the centrifuge procedure in order to create a methodology of testing...

  7. External ventricular drain causes brain tissue damage: an imaging study.

    Science.gov (United States)

    Ortolano, Fabrizio; Carbonara, Marco; Stanco, Antonella; Civelli, Vittorio; Carrabba, Giorgio; Zoerle, Tommaso; Stocchetti, Nino

    2017-10-01

    An external ventricular drain (EVD) is used to measure intracranial pressure (ICP) and to drain cerebrospinal fluid (CSF). The procedure is generally safe, but parenchymal sequelae are reported as a possible side effect, with variable incidence. We investigated the mechanical sequelae of EVD insertion and their clinical significance in acute brain-injured patients, with a special focus on hemorrhagic lesions. Mechanical sequelae of EVD insertion were detected in patients by computed tomography (CT) and magnetic resonance imaging (MRI), performed for clinical purposes. In 155 patients we studied the brain tissue surrounding the EVD by CT scan (all patients) and MRI (16 patients); 53 patients were studied at three time points (day 1-2, day 3-10, >10 days after EVD placement) to document the lesion time course. Small hemorrhages, with a hyperdense core surrounded by a hypodense area, were identified by CT scan in 33 patients. The initial average (hyper- + hypodense) lesion volume was 8.16 ml, increasing up to 15 ml by >10 days after EVD insertion. These lesions were not accompanied by neurologic deterioration or ICP elevation. History of arterial hypertension, coagulation abnormalities and multiple EVD insertions were significantly associated with hemorrhages. In 122 non-hemorrhagic patients, we detected very small hypodense areas (average volume 0.38 ml) surrounding the catheter. At later times these hypodensities slightly increased. MRI studies in 16 patients identified both intra- and extracellular edema around the catheters. The extracellular component increased with time. EVD insertion, even when there are no clinically important complications, causes a tissue reaction with minimal bleedings and small areas of brain edema.

  8. Head First jQuery

    CERN Document Server

    Benedetti, Ryan

    2011-01-01

    Want to add more interactivity and polish to your websites? Discover how jQuery can help you build complex scripting functionality in just a few lines of code. With Head First jQuery, you'll quickly get up to speed on this amazing JavaScript library by learning how to navigate HTML documents while handling events, effects, callbacks, and animations. By the time you've completed the book, you'll be incorporating Ajax apps, working seamlessly with HTML and CSS, and handling data with PHP, MySQL and JSON. If you want to learn-and understand-how to create interactive web pages, unobtrusive scrip

  9. Analysis of three-dimensional transient seepage into ditch drains ...

    Indian Academy of Sciences (India)

    Ratan Sarmah

    runs have been made use of to obtain solution to the con- sidered problem. Double Fourier runs have been made for tackling the boundary conditions and the triple Fourier run has been made to negotiate the initial condition of the problem. The transient expressions for the hydraulic head, top and side discharges pertinent ...

  10. Visual perception of axes of head rotation

    Directory of Open Access Journals (Sweden)

    David Mattijs Arnoldussen

    2013-02-01

    Full Text Available Registration of ego-motion is important to accurately navigate through space. Movements of the head and eye relative to space are registered through the vestibular system and optical flow, respectively. Here, we address three questions concerning the visual registration of self-rotation. 1. Eye-in-head movements provide a link between the motion signals received by sensors in the moving eye and sensors in the moving head. How are these signals combined into an ego-rotation percept? We combined optic flow of simulated forward and rotational motion of the eye with different levels of eye-in-head rotation for a stationary head. We dissociated simulated gaze rotation and head rotation by different levels of eye-in-head pursuit.We found that perceived rotation matches simulated head- not gaze-rotation. This rejects a model for perceived self-rotation that relies on the rotation of the gaze line. Rather, eye-in-head signals serve to transform the optic flow’s rotation information, that specifies rotation of the scene relative to the eye, into a rotation relative to the head. This suggests that transformed visual self-rotation signals may combine with vestibular signals.2. Do transformed visual self-rotation signals reflect the arrangement of the semicircular canals (SCC? Previously, we found sub-regions within MST and V6+ that respond to the speed of the simulated head rotation. Here, we re-analyzed those BOLD signals for the presence of a spatial dissociation related to the axes of visually simulated head rotation, such as have been found in sub-cortical regions of various animals. Contrary, we found a rather uniform BOLD response to simulated rotation along the three SCC axes.3. We investigated if subject’s sensitivity to the direction of the head rotation axis shows SCC axes specifcity. We found that sensitivity to head rotation is rather uniformly distributed, suggesting that in human cortex, visuo-vestibular integration is not arranged into

  11. Head Injuries in Soccer.

    Science.gov (United States)

    Myrick, Karen M

    2016-07-01

    Soccer is currently the most popular and fastest growing sport worldwide, with approximately 265 million registered soccer players existing around the world. The popularity of the sport, coupled with the high incidence of 18.8-21.5 head injuries per 1,000 player hours reported, make it essential that clinicians, coaches, and the athletes, have a solid understanding of head injuries. The successful rehabilitation of athletes with head injuries relies upon early and accurate identification strategies and implementation of appropriate return to play measures across all areas in the continuum of care. Soccer is a frequently played sport, and head injuries are common. Therefore, it is imperative that clinicians, coaches, and the athletes themselves have a solid understanding of head injury prevention, diagnosis, and treatment options. The purpose of this article was to provide rehabilitation nurses with current information regarding frequently occurring head injuries in the widespread sport of soccer. © 2015 Association of Rehabilitation Nurses.

  12. Cranial surgery without head shaving.

    Science.gov (United States)

    Tokimura, Hiroshi; Tajitsu, Kenichiro; Tsuchiya, Masahiro; Yamahata, Hitoshi; Taniguchi, Ayumi; Takayama, Kenji; Kaji, Masatomo; Hirabaru, Masashi; Hirayama, Takahisa; Shinsato, Tomomi; Arita, Kazunori

    2009-12-01

    Based on a series of 632 patients who underwent craniotomy without head shaving, we report the efficacy and safety of our simplified procedure and document the usefulness of the electrosurgical scalpel. After brushing a chlorhexidine-alcohol solution onto the craniotomy site, the hair was parted from the incision line and fixed with adhesive paper drapes. In recent cases, electrosurgical scalpels were used for scalp- and subcutaneous dissection. At the end of surgery, the wound was closed in the usual manner, taking care that no hair was in the wound and the hair and wound were rinsed with clean water in the operating room. We did not apply disinfectant for postoperative wound care, rather, the hair was shampooed on the 2nd, 4th, and 6th postoperative day. Among 632 patients who underwent cranial surgery without head shaving, only 7 (1.1%) developed postoperative wound infections. None of the 34 patients who underwent craniotomy using the electrosurgical scalpel developed wound infections. Our simplified cranial surgery without head shaving does not increase the risk of wound infection. Because the use of the electrosurgical scalpel for skin and soft tissue dissection minimizes bleeding, the probability of wound infection appears to be reduced.

  13. Head and Neck

    DEFF Research Database (Denmark)

    Højgaard, Liselotte; Berthelsen, Anne Kiil; Loft, Annika

    2014-01-01

    Positron emission tomography (PET)/computed tomography with FDG of the head and neck region is mainly used for the diagnosis of head and neck cancer, for staging, treatment evaluation, relapse, and planning of surgery and radio therapy. This article is a practical guide of imaging techniques......, including a detailed protocol for FDG PET in head and neck imaging, physiologic findings, and pitfalls in selected case stories....

  14. Source/Drain Engineering for High Performance Vertical MOSFET

    Science.gov (United States)

    Imamoto, Takuya; Endoh, Tetsuo

    In this paper, Source/Drain (S/i>/D) engineering for high performance (HP) Vertical MOSFET (V-MOSFET) in 3Xnm generation and its beyond is investigated, by using gradual S/i>/D profile while degradation of driving current (ION) due to the parasitic series resistance (Rpara) is minimized through two-dimensional device simulation taking into account for gate-induced-drain-leakage (GIDL). In general, it is significant to reduce spreading resistance in the case of conventional Planar MOSFET. Therefore, in this study, we focused and analyzed the abruptness of diffusion layer that is still importance parameter in V-MOSFET. First, for improving the basic device performance such as subthreshold swing (SS), ION, and Rpara, S/D engineering is investigated. The dependency of device performance on S/D abruptness (σS/D) for various Lightly Doped Drain Extension (LDD) abruptness (σLDD) is analyzed. In this study, Spacer Length (LSP) is defined as a function of σS/D. As σS/D becomes smaller and S/D becomes more abrupt, LSP becomes shorter. SS depends on the σS/D rather than the σLDD. ION has the peak value of 1750µA/µm at σS/D =2nm/dec. and σLDD=3nm/dec. when the silicon pillar diameter (D) is 30nm and the gate length (Lg) is 60nm. As σS/D becomes small, higher ION is obtained due to reduction of Rpara while SS is degraded. However, when σS/D becomes too small in the short channel devices (Lg =60nm and Lg =45nm), ION is degraded because the leakage current due to GIDL is increased and reaches IOFF limit of 100nA/µm. In addition, as σLDD becomes larger, larger ION is obtained in the case of Lg =100nm and Lg =60nm because channel length becomes shorter. On the other hand, in the case of Lg =45nm, as σLDD becomes larger, ION is degraded because short channel effect (SCE) becomes significant. Next, the dependency of the basic device performance on D is investigated. By slimming D from 30nm to 10nm, while SS is improved and approaches the ideal value of 60mV/Decade, ION

  15. Investigation of mechanisms governing electrowetting and hydrodynamic interactions in the presence of draining channels

    Science.gov (United States)

    Gupta, Rohini

    Modulation of solid-liquid interfacial interactions via electric field (or electrowetting) is an effective method to deform and move liquid drops on solid surfaces in micro-/nanoscale systems. The deformation and motion of a liquid drop on a solid surface in response to an external driving force is hindered by pinning of triple contact line. A better understanding of the mechanisms and limitations of electrowetting is warranted for design and optimization of active micro-/nanoscale systems. Modulation of hydrodynamic interactions via surface structures may contribute to the adhesion and locomotion mechanisms employed by tree frogs under flooded conditions: a better understanding of which will facilitate design of biomimetic systems inspired by the same. This thesis summarizes the results of investigation of the mechanisms and limitations of electrowetting (electrowetting on dielectric and potential-induced molecular reorganization) and the hydrodynamic interactions in the presence of draining channels. The mechanism at play during electrowetting on dielectric is probed via capillary condensation inside surface force apparatus. Height of a nanometer-sized annular water meniscus is measured and observed to be independent of the applied potential. These nanoscale electrowetting measurements unequivocally demonstrate that spreading of a liquid conductive drop on a charged dielectric is driven by electromechanics and not by a change in solid-liquid interfacial energy. Macroscopic electrowetting response of substrates with a range of contact angle hysteresis is characterized to quantify the relationship between contact angle hysteresis, threshold potential for liquid actuation, and electrowetting hysteresis. These results are interpreted within the electromechanical framework corrected for pinning of the moving triple contact line and demonstrate that the electrowetting hysteresis and the contact angle hysteresis are equal in magnitude. Alternatively, potential

  16. Influence of thinning operations on the hydrology of a drained coastal plantation watershed

    Science.gov (United States)

    Johnny M. Grace; R.W. Skaggs; H.R. Malcom; G.M. Chescheir; D.K. Cassel

    2003-01-01

    Forest management activities such as harvesting, thinning, and site preparation can affect the hydrologic behavior of watersheds on poorly drained soils. The effects of thinning on hydrology are presented for an artificially drained pine plantation paired watershed in eastern North Carolina. Outflow and water table depths were monitored over a 3-year study period...

  17. Mandibular impacted third molar Surgery and Drains: a review of the ...

    African Journals Online (AJOL)

    Oral surgeons have used drains after the surgical removal of mandibular impacted third molars to minimize postoperative morbidity with varying degrees of success. The use of a drain in association with primary suture after the surgical removal of the impacted lower third molars allows the patient to experience a more ...

  18. 77 FR 30886 - Virginia Graeme Baker Pool and Spa Safety Act; Interpretation of Unblockable Drain

    Science.gov (United States)

    2012-05-24

    ... Baker Pool and Spa Safety Act; Interpretation of Unblockable Drain AGENCY: Consumer Product Safety... interpretation of the term ``unblockable drain,'' as used in the Virginia Graeme Baker Pool and Spa Safety Act... document does not alter the current requirement that public pools and spas be in compliance with the VGBA...

  19. Laparoscopic elective cholecystectomy with and without drain: A controlled randomised trial

    Directory of Open Access Journals (Sweden)

    Gouda El-labban

    2012-01-01

    Full Text Available Background : Laparoscopic cholecystectomy is the main method of treatment of symptomatic gallstones. Routine drainage after laparoscopic cholecystectomy is an issue of considerable debate. Therefore, a controlled randomised trial was designed to assess the value of drains in elective laparoscopic cholecystectomy. Materials and Methods: During a two-year period (From April 2008 to January 2010, 80 patients were simply randomised to have a drain placed (group A, an 8-mm pentose tube drain was retained below the liver bed, whereas 80 patients were randomised not to have a drain (group B placed in the subhepatic space. End points of this trial were to detect any differences in morbidity, postoperative pain, wound infection and hospital stay between the two groups. Results : There was no mortality in either group and no statistically significant difference in postoperative pain, nausea and vomiting, wound infection or abdominal collection between the two groups. However, hospital stay was longer in the drain group than in group without drain and it is appearing that the use of drain delays hospital discharge. Conclusion : The routine use of a drain in non-complicated laparoscopic cholecystectomy has nothing to offer; in contrast, it is associated with longer hospital stay.

  20. Drain Tube-Induced Jejunal Penetration Masquerading as Bile Leak following Whipple’s Operation

    Directory of Open Access Journals (Sweden)

    Sang Ho Bae

    2011-05-01

    Full Text Available A 70-year-old man had undergone pancreaticoduodenectomy due to a distal common bile duct malignancy. After the operation, serous fluid discharge decreased from two drain tubes in the retroperitoneum. Over four weeks, the appearance of the serous fluid changed to a greenish bile color and the patient persistently drained over 300 ml/day. Viewed as bile leak at the choledochojejunostomy, treatment called for endoscopic diagnosis and therapy. Cap-fitted forward-viewing endoscopy demonstrated that the distal tip of a pancreatic drain catheter inserted at the pancreaticojejunostomy site had penetrated the opposite jejunum wall. One of the drain tubes primarily placed in the retroperitoneum had also penetrated the jejunum wall, with the distal tip positioned near the choledochojejunostomy site. No leak of contrast appeared beyond the jejunum or anastomosis site. Following repositioning of a penetrating catheter of the pancreaticojejunostomy, four days later, the patient underwent removal of two drain tubes without additional complications. In conclusion, the distal tip of the catheter, placed to drain pancreatic juice, penetrated the jejunum wall and may have caused localized perijejunal inflammation. The other drain tube, placed in the retroperitoneal space, might then have penetrated the inflamed wall of the jejunum, allowing persistent bile drainage via the drain tube. The results masqueraded as bile leakage following pancreaticoduodenectomy.

  1. The current state of the evidence for the use of drains in spinal surgery: systematic review.

    Science.gov (United States)

    Patel, Salil B; Griffiths-Jones, William; Jones, Conor S; Samartzis, Dino; Clarke, Andrew J; Khan, Shahid; Stokes, Oliver M

    2017-11-01

    Search for evidence pertaining to the effectiveness of drains used in spinal surgeries. PubMed and EMBASE databases were searched for articles pertaining to the use of drains in all types of spinal surgery. The bibliographies of relevant studies were searched for additional papers that met the initial inclusion criteria. Level I and II studies were scored according to guidelines in the Cochrane Collaboration Back Review Group. We utilised the Population, Intervention, Comparison, Outcomes and Study design (PICOS) method to define our study eligibility criteria. Nineteen papers were identified: four level I studies, eight level III studies and seven level IV studies. The four level I, involving the randomization of patients into 'drain' and 'non-drain' groups, identified a total of 363 patients. Seven of the eight level III retrospective studies concluded that the use of drains did not reduce complications. Two of the seven level IV studies agreed with this conclusion. The remaining five level IV studies reported the benefits of lumbar drainage following dural tears. There is a paucity of published literature on the use of drains following spinal surgery. This is the first study to assess the evidence for the benefits of drains post-operatively in spinal surgery. The identified studies have shown that drains do not reduce the incidence of complications in anterior cervical discectomy and fusion, one and two level posterior cervical fusions, lumbar laminectomies, lumbar decompressions or discectomies and posterior spinal fusion for adolescent scoliosis. Further level I and II studies are needed.

  2. 7 CFR 58.425 - Conveyor for moving and draining block or barrel cheese.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Conveyor for moving and draining block or barrel... and Grading Service 1 Equipment and Utensils § 58.425 Conveyor for moving and draining block or barrel cheese. The conveyor shall be constructed so that it will not contaminate the cheese and be easily...

  3. Filling, storing and draining. Three key aspects of landslide hydrology

    Science.gov (United States)

    Bogaard, Thom; Greco, Roberto

    2016-04-01

    Rainfall-triggered landslides are among the most widespread hazards in the world. The hydrology in and around a landslide area is key to pore pressure build-up in the soil skeleton which reduces shear strength due to the buoyancy force exerted by water in a saturated soil and to soil suction in an unsaturated soil. Extraordinary precipitation events trigger most of the landslides, but, at the same time, the vast majority of slopes do not fail. The intriguing question is: 'When and where exactly can a slope become triggered to slide and flow downwards?' The objective of this article is to present and discuss landslide hydrology at three scales - pore, hillslope, and catchment - which, taken together, give an overview of this interdisciplinary science. In fact, for rainfall-triggered landslides to occur, an unfavourable hydrological interplay should exist between fast and/or prolonged infiltration, and a relatively 'slow' drainage. The competition of water storage, pressure build-up and the subsequently induced drainage contains the importance of the timing, which is indisputably one of the more delicate but relevant aspects of landslide modelling, the overlay of hydrological processes with different time scales. As slopes generally remain stable, we can argue that effective drainage mechanisms spontaneously develop, as the best for a slope to stay stable is getting rid of the overload of water (above field capacity), either vertically or laterally. So, landslide hydrology could be framed as 'Filling-Storing-Draining'. Obviously, 'Storing' is added to stress the importance of dynamic pressure build-up for slope stability. 'Draining' includes all removal of water from the system (vertical and lateral flow, evaporation and transpiration) and thus pore water pressure release. Furthermore, by addressing landslide hydrology from both earth sciences and soil mechanics perspectives, we aim to manifest the hydrological processes in hillslopes and their influence on behaviour

  4. BRAIN DRAIN IN THE GLOBALIZATION ERA: THE CASE OF ROMANIA

    Directory of Open Access Journals (Sweden)

    MARIANA BĂLAN

    2017-06-01

    Full Text Available Migration is an old phenomenon in the history of humankind. However, the magnitude, complexity, and structure of migration flows in the global era are all unprecedented. According to the United Nations Report “Trends in International Migrant Stock: the 2015 Revision” at world level 244 million international migrants were recorded in 2015. With the increase in the number of migrants, the emigration of ‘high-skilled’ individuals is also growing. OECD and United Nation Statistics show that in the last decade the number of migrants with tertiary education increased by about 70%. Brain drain is also a well-known phenomenon. Highly educated individuals and scientists have travelled the world in all centuries in search of better study and research, and working conditions, and of new opportunities. Nowadays, in the era of globalisation and, implicitly, of swifter development of international markets, the emigration rate of high-skilled experts exceeds the total emigration rate, which shows the selectiveness of migration at educational level. The paper presents a brief analysis of the interdependencies between migration and globalisation and of the effects of globalisation on the migration of high-skilled individuals. The trends, structure, and volume of high-skilled labour force from Romania are analysed along with the effects generated by them.

  5. Hydraulic Capacity of an ADA Compliant Street Drain Grate

    Energy Technology Data Exchange (ETDEWEB)

    Lottes, Steven A. [Argonne National Lab. (ANL), Argonne, IL (United States); Bojanowski, Cezary [Argonne National Lab. (ANL), Argonne, IL (United States)

    2015-09-01

    Resurfacing of urban roads with concurrent repairs and replacement of sections of curb and sidewalk may require pedestrian ramps that are compliant with the American Disabilities Act (ADA), and when street drains are in close proximity to the walkway, ADA compliant street grates may also be required. The Minnesota Department of Transportation ADA Operations Unit identified a foundry with an available grate that meets ADA requirements. Argonne National Laboratory’s Transportation Research and Analysis Computing Center used full scale three dimensional computational fluid dynamics to determine the performance of the ADA compliant grate and compared it to that of a standard vane grate. Analysis of a parametric set of cases was carried out, including variation in longitudinal, gutter, and cross street slopes and the water spread from the curb. The performance of the grates was characterized by the fraction of the total volume flow approaching the grate from the upstream that was captured by the grate and diverted into the catch basin. The fraction of the total flow entering over the grate from the side and the fraction of flow directly over a grate diverted into the catch basin were also quantities of interest that aid in understanding the differences in performance of the grates. The ADA compliant grate performance lagged that of the vane grate, increasingly so as upstream Reynolds number increased. The major factor leading to the performance difference between the two grates was the fraction of flow directly over the grates that is captured by the grates.

  6. BRAIN DRAIN – BRAIN GAIN: SLOVAK STUDENTS AT CZECH UNIVERSITIES

    Directory of Open Access Journals (Sweden)

    FISCHER, Jakub

    2015-09-01

    Full Text Available The Slovak Republic is experiencing a growing brain drain of elite secondary school students. Slovak human capital flows chiefly to Czech Higher Education Institutes (HEIs. The aim of this paper is to analyse who these Slovak students are to create a complete profile of Slovak students at Czech HEIs. We used a unique dataset based on the surveys EUROSTUDENT V and DOKTORANDI 2014 to explore differences between Czech and Slovak students, their financial situation and the functionality of the intergenerational transmission mechanism. We have found that Slovak students at Czech HEIs come from highly educated families and from the middle and higher class families significantly more often than Czech students at Czech HEIs or Slovak students at Slovak HEIs. Approximately 80% of them came from grammar schools. Slovak students also often have better language skills. We have discovered that Slovak students at Czech HEIs enjoy certain social benefits, slightly more often they have higher monthly income compared to Czech students, and they work slightly less often during their studies. Finally, according to our findings, Slovak doctoral students are often reluctant to return back to the Slovak Republic or to stay in the Czech Republic.

  7. Oculo-peritoneal shunt: draining aqueous humor to the peritoneum

    Directory of Open Access Journals (Sweden)

    Ana Maldonado-Junyent

    2015-04-01

    Full Text Available In 2010, there were estimated to be approximately 60.5 million people with glaucoma. This number is expected to increase to 79.6 million by 2020. In 2010, there were 8.4 million people with bilateral blindness caused by glaucoma, and this number is expected in increase to 11.2 million by 2020. Filtering implants are special devices that have been developed to reduce intraocular pressure in patients with refractory glaucoma. The success rate of these implants is relatively low, and they continue to fail over time. To avoid failure caused by the formation of scar tissue around the implants, attempts have been made to drain the aqueous humor to various sites, including the venous system, lacrimal sac, sinuses, and conjunctival fornix. Recently, a system to shunt aqueous humor from the anterior chamber to the peritoneum has been developed. The surgical technique involved in this system is a modification of the technique currently used by neurosurgeons for the treatment of hydrocephalus. We present the first case operated using this technique.

  8. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... Computed tomography (CT) of the head uses special x-ray equipment to help assess head injuries, severe headaches, ... is a diagnostic medical test that, like traditional x-rays, produces multiple images or pictures of the inside ...

  9. Head Injuries in Children

    Science.gov (United States)

    Pennington, Nicole

    2010-01-01

    School nurses play a crucial role in injury prevention and initial treatment when injuries occur at school. The role of school nurses includes being knowledgeable about the management of head injuries, including assessment and initial treatment. The school nurse must be familiar with the outcomes of a head injury and know when further evaluation…

  10. Abnormal Head Position

    Science.gov (United States)

    ... non-ocular causes of an abnormal head position? Congenital shortening of the neck muscles (sternocleidomastoid) can cause a head tilt. This is ... amblyopia) are other treatment alternatives. Physical therapy helps congenital torticollis from tight neck muscles. Updated ... Terms & Conditions Most Common ...

  11. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... the limitations of CT Scanning of the Head? What is CT Scanning of the Head? Computed tomography, more commonly known as a CT or CAT scan, is a diagnostic medical test that, like traditional x-rays, produces multiple images or pictures of the inside of ...

  12. Head Start in Action.

    Science.gov (United States)

    Riley, Clara M. D.; Epps, Frances M. J.

    Records and observations from a summer Head Start program, conducted in Los Angeles by Delta Sigma Theta, are delineated in this book. It relates firsthand experiences of the participating personnel as they developed and implemented a Head Start program for some 300 children. The book is divided into three sections. Section I,…

  13. Bloodstream infection following 217 consecutive systemic-enteric drained pancreas transplants

    Directory of Open Access Journals (Sweden)

    Mark Walter

    2006-08-01

    Full Text Available Abstract Background Combined kidney pancreas transplantation (PTx evolved as excellent treatment for diabetic nephropathy. Infections remain common and serious complications. Methods 217 consecutive enteric drained PTxs performed from 1997 to 2004 were retrospectively analyzed with regard to bloodstream infection. Immunosuppression consisted of antithymocyteglobuline induction, tacrolimus, mycophenolic acid and steroids for the majority of cases. Standard perioperative antimicrobial prophylaxis consisted of pipercillin/tazobactam in combination with ciprofloxacin and fluconazole. Results One year patient, pancreas and kidney graft survival were 96.4%, 88.5% and 94.8%, surgical complication rate was 35%, rejection rate 30% and rate of infection 59%. In total 46 sepsis episodes were diagnosed in 35 patients (16% with a median onset on day 12 (range 1–45 post transplant. Sepsis source was intraabdominal infection (IAI (n = 21, a contaminated central venous line (n = 10, wound infection (n = 5, urinary tract infection (n = 2 and graft transmitted (n = 2. Nine patients (4% experienced multiple episodes of sepsis. Overall 65 pathogens (IAI sepsis 39, line sepsis 15, others 11 were isolated from blood. Gram positive cocci accounted for 50 isolates (77%: Coagulase negative staphylococci (n = 28, i.e. 43% (nine multi-resistant, Staphylococcus aureus (n = 11, i.e. 17% (four multi-resistant, enterococci (n = 9, i.e. 14% (one E. faecium. Gram negative rods were cultured in twelve cases (18%. Patients with blood borne infection had a two year pancreas graft survival of 76.5% versus 89.4% for those without sepsis (p = 0.036, patient survival was not affected. Conclusion Sepsis remains a serious complication after PTx with significantly reduced pancreas graft, but not patient survival. The most common source is IAI.

  14. Historical peat loss explains limited short-term response of drained blanket bogs to rewetting.

    Science.gov (United States)

    Williamson, Jennifer; Rowe, Edwin; Reed, David; Ruffino, Lucia; Jones, Peter; Dolan, Rachel; Buckingham, Helen; Norris, David; Astbury, Shaun; Evans, Chris D

    2017-03-01

    This study assessed the short-term impacts of ditch blocking on water table depth and vegetation community structure in a historically drained blanket bog. A chronosequence approach was used to compare vegetation near ditches blocked 5 years, 4 years and 1 year prior to the study with vegetation near unblocked ditches. Plots adjacent to and 3 m away from 70 ditches within an area of blanket bog were assessed for floristic composition, aeration depth using steel bars, and topography using LiDAR data. No changes in aeration depth or vegetation parameters were detected as a function of ditch-blocking, time since blocking, or distance from the ditch, with the exception of non-Sphagnum bryophytes which had lower cover in quadrats adjacent to ditches that had been blocked for 5 years. Analysis of LiDAR data and the observed proximity of the water table to the peat surface led us to conclude that the subdued ecosystem responses to ditch-blocking were the result of historical peat subsidence within a 4-5 m zone either side of each ditch, which had effectively lowered the peat surface to the new, ditch-influenced water table. We estimate that this process led to the loss of around 500,000 m3 peat within the 38 km2 study area following drainage, due to a combination of oxidation and compaction. Assuming that 50% of the volume loss was due to oxidation, this amounts to a carbon loss of 11,000 Mg C over this area, i.e. 3 Mg C ha-1. The apparent 'self-rewetting' of blanket bogs in the decades following drainage has implications for their restoration as it suggests that there may not be large quantities of dry peat left to rewet, and that there is a risk of inundation (potentially leading to high methane emissions) along subsided ditch lines. Many peatland processes are likely to be maintained in drained blanket bog, including support of typical peatland vegetation, but infilling of lost peat and recovery of original C stocks are likely to take longer than is generally

  15. Rainfall, discharge, and water-quality data during stormwater monitoring, H-1 storm drain, Oahu, Hawaii, July 1, 2009, to June 30, 2010

    Science.gov (United States)

    Presley, Todd K.; Jamison, Marcael T.J.

    2010-01-01

    Canal. The discrete samples were analyzed for some or all of the following constituents: total suspended solids, nutrients, oil and grease, and selected dissolved (filtered) trace metals (cadmium, chromium, nickel, copper, lead, and zinc). Five quality-assurance/quality-control samples were analyzed during the year. These samples included one laboratory-duplicate, one field-duplicate, and one matrix-spike sample prepared and analyzed with the storm samples. In addition, two inorganic blank-water samples, one sample at the H-1 storm drain and one sample at the Manoa-Palolo Drainage Canal, were collected by running the blank water (water purified of all inorganic constituents) through the sampling and processing systems after cleaning automatic sampler lines to verify that the sampling lines were not contaminated.

  16. Oxic limestone drains for treatment of dilute, acidic mine drainage

    Science.gov (United States)

    Cravotta, Charles A.

    1998-01-01

    Limestone treatment systems can be effective for remediation of acidic mine drainage (AMD) that contains moderate concentrations of dissolved O2 , Fe3+ , or A13+ (1‐5 mg‐L‐1 ). Samples of water and limestone were collected periodically for 1 year at inflow, outflow, and intermediate points within underground, oxic limestone drains (OLDs) in Pennsylvania to evaluate the transport of dissolved metals and the effect of pH and Fe‐ and Al‐hydrolysis products on the rate of limestone dissolution. The influent was acidic and relatively dilute (pH 1 mg‐L‐1 ) but was near neutral (pH = 6.2‐7.0); Fe and Al decreased to less than 5% of influent concentrations. As pH increased near the inflow, hydrous Fe and Al oxides precipitated in the OLDs. The hydrous oxides, nominally Fe(OH)3 and AI(OH)3, were visible as loosely bound, orange‐yellow coatings on limestone near the inflow. As time elapsed, Fe(OH)3 and AI(OH)3 particles were transported downflow. During the first 6 months of the experiment, Mn 2+ was transported conservatively through the OLDs; however, during the second 6 months, concentrations of Mn in effluent decreased by about 50% relative to influent. The accumulation of hydrous oxides and elevated pH (>5) in the downflow part of the OLDs promoted sorption and coprecipitation of Mn as indicated by its enrichment relative to Fe in hydrous‐oxide particles and coatings on limestone. Despite thick (~1 mm) hydrous‐oxide coatings on limestone near the inflow, CaCO3 dissolution was more rapid near the inflow than at downflow points within the OLD where the limestone was not coated. The rate of limestone dissolution decreased with increased residence time, pH, and concentrations of Ca2+ and HCO3‐ and decreased PCO2. The following overall reaction shows alkalinity as an ultimate product of the iron hydrolysis reaction in an OLD:Fe2+ + 0.25 O2 +CaCO3 + 2.5 H2O --> Fe(OH)3 + 2 Ca2+ + 2 HCO3-where 2 moles of CaCO3 dissolve for each mole of Fe(OH)3 produced

  17. Homogenization of one-dimensional draining through heterogeneous porous media including higher-order approximations

    Science.gov (United States)

    Anderson, Daniel M.; McLaughlin, Richard M.; Miller, Cass T.

    2018-02-01

    We examine a mathematical model of one-dimensional draining of a fluid through a periodically-layered porous medium. A porous medium, initially saturated with a fluid of a high density is assumed to drain out the bottom of the porous medium with a second lighter fluid replacing the draining fluid. We assume that the draining layer is sufficiently dense that the dynamics of the lighter fluid can be neglected with respect to the dynamics of the heavier draining fluid and that the height of the draining fluid, represented as a free boundary in the model, evolves in time. In this context, we neglect interfacial tension effects at the boundary between the two fluids. We show that this problem admits an exact solution. Our primary objective is to develop a homogenization theory in which we find not only leading-order, or effective, trends but also capture higher-order corrections to these effective draining rates. The approximate solution obtained by this homogenization theory is compared to the exact solution for two cases: (1) the permeability of the porous medium varies smoothly but rapidly and (2) the permeability varies as a piecewise constant function representing discrete layers of alternating high/low permeability. In both cases we are able to show that the corrections in the homogenization theory accurately predict the position of the free boundary moving through the porous medium.

  18. Maintenance of agricultural drains alters physical habitat, but not macroinvertebrate assemblages exploited by fishes.

    Science.gov (United States)

    Ward-Campbell, Belinda; Cottenie, Karl; Mandrak, Nicholas; McLaughlin, Robert

    2017-12-01

    The effects of drain maintenance on fish habitat and benthic macroinvertebrate assemblages (fish prey) were investigated for eight agricultural drains in southwestern Ontario, Canada. Our investigation employed a replicated Before-After-Control-Impact (BACI) design where each maintained section of a drain was paired with an unmaintained section downstream and an unmaintained section on a nearby reference drain of similar size and position in the watershed. Seven variables characterizing physical habitat features important to fishes and three variables characterizing the taxonomic abundance, densities, and relative densities of benthic macroinvertebrates were measured before drain maintenance and 10-12 times over 2 years following maintenance. Pulse responses were detected for three habitat variables quantifying vegetative cover: percent vegetation on the bank, percent in-stream vegetation, and percent cover. All three variables returned to pre-maintenance levels within two years of maintenance. No consistent changes were observed in the remaining habitat features or in the richness and densities of benthic invertebrate assemblages following drain maintenance. Our findings suggest that key features of fish habitat, structural properties and food availability, are resistant to drain maintenance. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Effects of pond draining on biodiversity and water quality of farm ponds.

    Science.gov (United States)

    Usio, Nisikawa; Imada, Miho; Nakagawa, Megumi; Akasaka, Munemitsu; Takamura, Noriko

    2013-12-01

    Farm ponds have high conservation value because they contribute significantly to regional biodiversity and ecosystem services. In Japan pond draining is a traditional management method that is widely believed to improve water quality and eradicate invasive fish. In addition, fishing by means of pond draining has significant cultural value for local people, serving as a social event. However, there is a widespread belief that pond draining reduces freshwater biodiversity through the extirpation of aquatic animals, but scientific evaluation of the effectiveness of pond draining is lacking. We conducted a large-scale field study to evaluate the effects of pond draining on invasive animal control, water quality, and aquatic biodiversity relative to different pond-management practices, pond physicochemistry, and surrounding land use. The results of boosted regression-tree models and analyses of similarity showed that pond draining had little effect on invasive fish control, water quality, or aquatic biodiversity. Draining even facilitated the colonization of farm ponds by invasive red swamp crayfish (Procambarus clarkii), which in turn may have detrimental effects on the biodiversity and water quality of farm ponds. Our results highlight the need for reconsidering current pond management and developing management plans with respect to multifunctionality of such ponds. Efectos del Drenado de Estanques sobre la Biodiversidad y la Calidad del Agua en Estanques de Cultivo. © 2013 Society for Conservation Biology.

  20. Inverse problem in anisotropic poroelasticity: Drained constants from undrained ultrasound measurements

    Energy Technology Data Exchange (ETDEWEB)

    Berryman, J.G.; Nakagawa, S.

    2009-11-20

    Poroelastic analysis has traditionally focused on the relationship between dry or drained constants which are assumed known and the saturated or undrained constants which are assumed unknown. However, there are many applications in this field of study for which the main measurements can only be made on the saturated/undrained system, and then it is uncertain what the eects of the uids were on the system, since the drained constants remain a mystery. The work presented here shows how to deduce drained constants from undrained constants for anisotropic systems having symmetries ranging from isotropic to orthotropic. Laboratory ultrasound data are then inverted for the drained constants in three granular packings: one of glass beads, and two others for distinct types of more or less angular sand grain packings. Experiments were performed under uniaxial stress, which resulted in hexagonal (transversely isotropic) symmetry of the poroelastic response. One important conclusion from the general analysis is that the drained constants are uniquely related to the undrained constants, assuming that porosity, grain bulk modulus, and pore uid bulk modulus are already known. Since the resulting system of equations for all the drained constants is linear, measurement error in undrained constants also propagates linearly into the computed drained constants.

  1. Stormwater drains and catch basins as sources for production of Aedes aegypti and Culex quinquefasciatus.

    Science.gov (United States)

    Arana-Guardia, Roger; Baak-Baak, Carlos M; Loroño-Pino, María Alba; Machain-Williams, Carlos; Beaty, Barry J; Eisen, Lars; García-Rejón, Julián E

    2014-06-01

    We present data showing that structures serving as drains and catch basins for stormwater are important sources for production of the mosquito arbovirus vectors Aedes aegypti and Culex quinquefasciatus in Mérida City, México. We examined 1761 stormwater drains - located in 45 different neighborhoods spread across the city - over dry and wet seasons from March 2012 to March 2013. Of the examined stormwater drains, 262 (14.9%) held water at the time they were examined and 123 yielded mosquito immatures. In total, we collected 64,560 immatures representing nine species. The most commonly encountered species were Cx. quinquefasciatus (n=39,269) and Ae. aegypti (n=23,313). Ae. aegypti and Cx. quinquefasciatus were collected during all 11 months when we found water-filled stormwater drains, and both were found in stormwater drains located throughout Mérida City. We also present data for associations between structural characteristics of stormwater drains or water-related characteristics and the abundance of mosquito immatures. In conclusion, stormwater drains produce massive numbers of Ae. aegypti and Cx. quinquefasciatus across Mérida City, both in the wet and dry seasons, and represent non-residential development sites that should be strongly considered for inclusion in the local mosquito surveillance and control program. Copyright © 2014. Published by Elsevier B.V.

  2. Assessing the biodegradability of microparticles disposed down the drain.

    Science.gov (United States)

    McDonough, Kathleen; Itrich, Nina; Casteel, Kenneth; Menzies, Jennifer; Williams, Tom; Krivos, Kady; Price, Jason

    2017-05-01

    Microparticles made from naturally occurring materials or biodegradable plastics such as poly(3-hydroxy butyrate)-co-(3-hydroxy valerate), PHBV, are being evaluated as alternatives to microplastics in personal care product applications but limited data is available on their ultimate biodegradability (mineralization) in down the drain environmental compartments. An OECD 301B Ready Biodegradation Test was used to quantify ultimate biodegradability of microparticles made of PHBV foam, jojoba wax, beeswax, rice bran wax, stearyl stearate, blueberry seeds and walnut shells. PHBV polymer was ready biodegradable reaching 65.4 ± 4.1% evolved CO2 in 5 d and 90.5 ± 3.1% evolved CO2 in 80 d. PHBV foam microparticles (125-500 μm) were mineralized extensively with >66% CO2 evolution in 28 d and >82% CO2 evolution in 80 d. PHBV foam microparticles were mineralized at a similar rate and extent as microparticles made of jojoba wax, beeswax, rice bran wax, and stearyl stearate which reached 84.8  ± 4.8, 84.9  ± 2.2, 82.7  ± 4.7, and 86.4 ± 3.2% CO2 evolution respectively in 80 d. Blueberry seeds and walnut shells mineralized more slowly only reaching 39.3  ± 6.9 and 5.1 ± 2.8% CO2 evolution in 80 d respectively. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Seasonal thaw settlement at drained thermokarst lake basins, Arctic Alaska

    Science.gov (United States)

    Liu, Lin; Schaefer, Kevin; Gusmeroli, Alessio; Grosse, Guido; Jones, Benjamin M.; Zhang, Tinjun; Parsekian, Andrew; Zebker, Howard

    2014-01-01

    Drained thermokarst lake basins (DTLBs) are ubiquitous landforms on Arctic tundra lowland. Their dynamic states are seldom investigated, despite their importance for landscape stability, hydrology, nutrient fluxes, and carbon cycling. Here we report results based on high-resolution Interferometric Synthetic Aperture Radar (InSAR) measurements using space-borne data for a study area located on the North Slope of Alaska near Prudhoe Bay, where we focus on the seasonal thaw settlement within DTLBs, averaged between 2006 and 2010. The majority (14) of the 18 DTLBs in the study area exhibited seasonal thaw settlement of 3–4 cm. However, four of the DTLBs examined exceeded 4 cm of thaw settlement, with one basin experiencing up to 12 cm. Combining the InSAR observations with the in situ active layer thickness measured using ground penetrating radar and mechanical probing, we calculated thaw strain, an index of thaw settlement strength along a transect across the basin that underwent large thaw settlement. We found thaw strains of 10–35% at the basin center, suggesting the seasonal melting of ground ice as a possible mechanism for the large settlement. These findings emphasize the dynamic nature of permafrost landforms, demonstrate the capability of the InSAR technique to remotely monitor surface deformation of individual DTLBs, and illustrate the combination of ground-based and remote sensing observations to estimate thaw strain. Our study highlights the need for better description of the spatial heterogeneity of landscape-scale processes for regional assessment of surface dynamics on Arctic coastal lowlands.

  4. Baseline head in Olkiluoto

    Energy Technology Data Exchange (ETDEWEB)

    Ahokas, H.; Tammisto, E.; Lehtimaeki, T. (Poeyry Environment Oy, Vantaa (Finland))

    2008-11-15

    As part of the programme for the final disposal of the spent nuclear fuel, Posiva Oy investigates the prevailing hydrological conditions on Olkiluoto island. The hydrological investigations have included several kinds of hydrological tests such as measurements of hydraulic conductivity by flow logging and a double-packer tool as well as interference tests by pumping, in order to study the hydraulic connections between the drillholes. In addition, long-term monitoring of groundwater level and groundwater head as well as measurements of flow conditions in open drillholes, groundwater salinity (in situ EC), precipitation (including snow), sea-water level, surface flow (runoff) etc. have been part of the investigation programme aiming at the characterization of the bedrock. The data have been used in the compilation of deterministic hydro-zones and hydraulic properties for numerical flow modelling to study the flow pattern on Olkiluoto island. In addition, the compiled bedrock models have been used in the planning of the repository layout and in the analyses of the transport of radionuclides and the functionality of engineered barriers. This report focuses on the measurements of groundwater head by means of multi-packers and in connection with flow loggings. The determination of the undisturbed groundwater head (baseline head) in terms of the in situ fresh water head is the main goal of this report. The density of groundwater is strongly dependent on salinity and due to the saline groundwater deep in the bedrock in Olkiluoto the term fresh water head is used instead of hydraulic head. Taking the density of groundwater into account, the gradient of the residual pressure, which actually causes groundwater flow can be calculated. The measured and calculated heads are converted into corresponding in situ fresh water heads, which correspond to the water level (metres above sea level) in the hose that runs from the packed-off section to the ground surface. This means that

  5. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... the limitations of MRI of the Head? What is MRI of the Head? Magnetic resonance imaging (MRI) is a noninvasive ... top of page What are some common uses of the procedure? MR imaging of the head is ...

  6. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... MRI of the Head? What is MRI of the Head? Magnetic resonance imaging (MRI) is a noninvasive ... of page What are some common uses of the procedure? MR imaging of the head is performed ...

  7. Use of multiple drains after mastectomy is associated with more patient discomfort and longer postoperative stay.

    Science.gov (United States)

    Saratzis, Athanasios; Soumian, Soni; Willetts, Rachel; Rastall, Sarah; Stonelake, Paul S

    2009-11-01

    Seromas constitute a common complication following surgery for breast cancer, and closed drainage is used routinely to reduce its incidence. The aim of this study was to evaluate the influence of number of drains on patient discomfort, seroma formation, and hospital stay during the immediate postoperative period after mastectomy for breast cancer. Based on a retrospective review of our clinical database, 110 consecutive patients from January 2004 through January 2006 who had undergone a mastectomy and axillary clearance for breast cancer were sent a simple postal questionnaire for collection of data. A total of 70 patients responded (all women; mean age, 69.4 +/- 11.4 years). Twenty-seven patients (38.57%) had 3 drains implanted unilaterally, 24 (34.28%) had 2, and 19 (27.14%) had 1 drain. They were divided into 2 groups: the first group with 1 drain (19 patients) and the other with 2 or 3 drains (51 patients). Median postoperative hospital stay was 2 days (range, 1-8 days); patients with 1 drain had a significantly shorter postoperative hospital stay (median, 2 days [range, 1-4 days] vs. 2 days [range, 1-8 days]; Mann-Whitney U test, P = .02). A total of 15 patients (21.43%) complained of a seroma. There was no difference in seroma rates between groups. Patients who had a single drain implanted had a significantly lower rate of discomfort (median, 2 [range, 1-5] vs. 3 [range, 1-7]; Mann-Whitney U test; P = .04). The number of drains used after a mastectomy for breast cancer did not significantly affect the rate or amount of seromas in this study, but the use of a single drain after mastectomy was significantly associated with less discomfort and shorter postoperative hospital stay.

  8. Ulnar head replacement.

    Science.gov (United States)

    Herbert, Timothy J; van Schoonhoven, Joerg

    2007-03-01

    Recent years have seen an increasing awareness of the anatomical and biomechanical significance of the distal radioulnar joint (DRUJ). With this has come a more critical approach to surgical management of DRUJ disorders and a realization that all forms of "excision arthroplasty" can only restore forearm rotation at the expense of forearm stability. This, in turn, has led to renewed interest in prosthetic replacement of the ulnar head, a procedure that had previously fallen into disrepute because of material failures with early implants, in particular, the Swanson silicone ulnar head replacement. In response to these early failures, a new prosthesis was developed in the early 1990s, using materials designed to withstand the loads across the DRUJ associated with normal functional use of the upper limb. Released onto the market in 1995 (Herbert ulnar head prosthesis), clinical experience during the last 10 years has shown that this prosthesis is able to restore forearm function after ulnar head excision and that the materials (ceramic head and noncemented titanium stem), even with normal use of the limb, are showing no signs of failure in the medium to long term. As experience with the use of an ulnar head prosthesis grows, so does its acceptance as a viable and attractive alternative to more traditional operations, such as the Darrach and Sauve-Kapandji procedures. This article discusses the current indications and contraindications for ulnar head replacement and details the surgical procedure, rehabilitation, and likely outcomes.

  9. Drainage of shallow peat harvesting areas with pipe drains; Mataloituneen turvekentaen kuivatus putkisalaojilla

    Energy Technology Data Exchange (ETDEWEB)

    Klemetti, V.; Saenkiaho, K. [Vapo Oy, Jyvaeskylae (Finland); Rautiainen, O. [Ojamarkkinointi Oy, Heinola (Finland)

    1996-12-31

    This study aims to develop pipe draining technics in peat harvesting areas, which have been in active use so long time that the remaining peat layer is about one meter thick. The method should be technically and economically feasible as well as environmentally acceptable. Special attention is paid to pipe installation techniques, drain spacing and impacts on watercourses, which receive the drainage waters. After pipe installation the area is monitored by measuring pipe runoffs, water tables, moisture content of peat and quality of drain water

  10. An exact solution to the draining reservoir problem of the incompressible and non-viscous liquid

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Seok-In [Department of Science Education, Gyeongin National University of Education, Anyang 430-739 (Korea, Republic of)], E-mail: sihongtao@hanmail.net

    2009-03-15

    The exact expressions for the drain time and the height, velocity and acceleration of the free surface are found for the draining reservoir problem of the incompressible and non-viscous liquid. Contrary to the conventional approximate results, they correctly describe the initial time dependence of the liquid velocity and acceleration. Torricelli's law does not hold in the initial transient region, which imposes restrictions on the validity of the analogy between the drain system and the electric circuit (Ohm's law)

  11. Drainage of shallow peat harvesting areas with pipe drains; Madaltuneen turvetuotantokentaen kuivatustutkimus

    Energy Technology Data Exchange (ETDEWEB)

    Klemetti, V. [Vapo Oy, Jyvaeskylae (Finland)

    1997-12-01

    This study aims to develop pipe draining techniques in peat harvesting areas, which have been in active use so long time that the remaining peat layer is about one meter thick. The method should be technically and economically feasible as well as environmentally acceptable. Special attention is paid to pipe installation techniques, drain spacing and impacts on watercourses, which receive the drainage waters. After pipe installation the area was monitored by measuring pipe runoffs, water tables, moisture content of peat and quality of drain water. These are the results of second year. (orig.)

  12. Detecting peatland drains with Object Based Image Analysis and Geoeye-1 imagery

    Directory of Open Access Journals (Sweden)

    J. Connolly

    2017-03-01

    Full Text Available Abstract Background Peatlands play an important role in the global carbon cycle. They provide important ecosystem services including carbon sequestration and storage. Drainage disturbs peatland ecosystem services. Mapping drains is difficult and expensive and their spatial extent is, in many cases, unknown. An object based image analysis (OBIA was performed on a very high resolution satellite image (Geoeye-1 to extract information about drain location and extent on a blanket peatland in Ireland. Two accuracy assessment methods: Error matrix and the completeness, correctness and quality (CCQ were used to assess the extracted data across the peatland and at several sub sites. The cost of the OBIA method was compared with manual digitisation and field survey. The drain maps were also used to assess the costs relating to blocking drains vs. a business-as-usual scenario and estimating the impact of each on carbon fluxes at the study site. Results The OBIA method performed well at almost all sites. Almost 500 km of drains were detected within the peatland. In the error matrix method, overall accuracy (OA of detecting the drains was 94% and the kappa statistic was 0.66. The OA for all sub-areas, except one, was 95–97%. The CCQ was 85%, 85% and 71% respectively. The OBIA method was the most cost effective way to map peatland drains and was at least 55% cheaper than either field survey or manual digitisation, respectively. The extracted drain maps were used constrain the study area CO2 flux which was 19% smaller than the prescribed Peatland Code value for drained peatlands. Conclusions The OBIA method used in this study showed that it is possible to accurately extract maps of fine scale peatland drains over large areas in a cost effective manner. The development of methods to map the spatial extent of drains is important as they play a critical role in peatland carbon dynamics. The objective of this study was to extract data on the spatial extent of

  13. Detecting peatland drains with Object Based Image Analysis and Geoeye-1 imagery.

    Science.gov (United States)

    Connolly, J; Holden, N M

    2017-12-01

    Peatlands play an important role in the global carbon cycle. They provide important ecosystem services including carbon sequestration and storage. Drainage disturbs peatland ecosystem services. Mapping drains is difficult and expensive and their spatial extent is, in many cases, unknown. An object based image analysis (OBIA) was performed on a very high resolution satellite image (Geoeye-1) to extract information about drain location and extent on a blanket peatland in Ireland. Two accuracy assessment methods: Error matrix and the completeness, correctness and quality (CCQ) were used to assess the extracted data across the peatland and at several sub sites. The cost of the OBIA method was compared with manual digitisation and field survey. The drain maps were also used to assess the costs relating to blocking drains vs. a business-as-usual scenario and estimating the impact of each on carbon fluxes at the study site. The OBIA method performed well at almost all sites. Almost 500 km of drains were detected within the peatland. In the error matrix method, overall accuracy (OA) of detecting the drains was 94% and the kappa statistic was 0.66. The OA for all sub-areas, except one, was 95-97%. The CCQ was 85%, 85% and 71% respectively. The OBIA method was the most cost effective way to map peatland drains and was at least 55% cheaper than either field survey or manual digitisation, respectively. The extracted drain maps were used constrain the study area CO 2 flux which was 19% smaller than the prescribed Peatland Code value for drained peatlands. The OBIA method used in this study showed that it is possible to accurately extract maps of fine scale peatland drains over large areas in a cost effective manner. The development of methods to map the spatial extent of drains is important as they play a critical role in peatland carbon dynamics. The objective of this study was to extract data on the spatial extent of drains on a blanket bog in the west of Ireland. The

  14. Computed Tomography (CT) -- Head

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    Full Text Available ... you! Do you have a personal story about radiology? Share your patient story here Images × Image Gallery ... Pregnancy Head and Neck Cancer X-ray, Interventional Radiology and Nuclear Medicine Radiation Safety Images related to ...

  15. Computed Tomography (CT) -- Head

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    Full Text Available ... Tomography (CT) Safety During Pregnancy Head and Neck Cancer X-ray, Interventional Radiology and Nuclear ... or other physician. To locate a medical imaging or radiation oncology provider in your community, you can search the ...

  16. Overview of Head Injuries

    Science.gov (United States)

    ... brain. If the head injury is very severe, mechanical ventilation may be used. Doctors control blood pressure and minimize the amount of brain swelling by adjusting the amount of intravenous fluids given and sometimes by giving intravenous drugs that ...

  17. Computed Tomography (CT) -- Head

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    Full Text Available ... headaches, dizziness, and other symptoms of aneurysm, bleeding, stroke and brain tumors. It also helps your doctor ... scanning provides more detailed information on head injuries, stroke , brain tumors and other brain diseases than regular ...

  18. Computed Tomography (CT) -- Head

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    Full Text Available ... be necessary. Your doctor will explain the exact reason why another exam is requested. Sometimes a follow- ... limitations of CT Scanning of the Head? A person who is very large may not fit into ...

  19. Computed Tomography (CT) -- Head

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    Full Text Available ... medically necessary because of potential risk to the baby. This risk is, however, minimal with head CT ... intravenous contrast indicate mothers should not breastfeed their babies for 24-48 hours after contrast medium is ...

  20. Computed Tomography (CT) -- Head

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    Full Text Available ... assess head injuries, severe headaches, dizziness, and other symptoms of aneurysm, bleeding, stroke and brain tumors. It ... within the brain shortly after a patient exhibits symptoms of a stroke. a stroke, especially with a ...

  1. Computed Tomography (CT) -- Head

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    Full Text Available ... scans in children should always be done with low-dose technique. top of page What are the ... page Additional Information and Resources RTAnswers.org Radiation Therapy for Brain Tumors Radiation Therapy for Head and ...

  2. Computed Tomography (CT) -- Head

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    Full Text Available ... this tunnel. Rotating around you, the x-ray tube and electronic x-ray detectors are located opposite ... medically necessary because of potential risk to the baby. This risk is, however, minimal with head CT ...

  3. Computed Tomography (CT) -- Head

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    Full Text Available ... microphone. top of page How does the procedure work? In many ways CT scanning works very much ... head CT scanning. Manufacturers of intravenous contrast indicate mothers should not breastfeed their babies for 24-48 ...

  4. Computed Tomography (CT) -- Head

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    Full Text Available ... special x-ray equipment to help assess head injuries, severe headaches, dizziness, and other symptoms of aneurysm, ... cancer. In emergency cases, it can reveal internal injuries and bleeding quickly enough to help save lives. ...

  5. Computed Tomography (CT) -- Head

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    Full Text Available ... traditional x-rays, particularly of soft tissues and blood vessels. CT scanning provides more detailed information on head injuries, stroke , brain tumors and other brain diseases than regular radiographs (x-rays). top of page ...

  6. Computed Tomography (CT) -- Head

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    Full Text Available ... used to detect: bleeding, brain injury and skull fractures in patients with head injuries. bleeding caused by ... a few seconds, and even faster in small children. Such speed is beneficial for all patients but ...

  7. TCGA head Neck

    Science.gov (United States)

    Investigators with The Cancer Genome Atlas (TCGA) Research Network have discovered genomic differences – with potentially important clinical implications – in head and neck cancers caused by infection with the human papillomavirus (HPV).

  8. Computed Tomography (CT) -- Head

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    Full Text Available ... microphone. top of page How does the procedure work? In many ways CT scanning works very much ... for Head and Neck Cancer Others American Stroke Association National Stroke Association top of page This page ...

  9. Computed Tomography (CT) -- Head

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    Full Text Available ... images of internal organs, bones, soft tissue and blood vessels provide greater detail than traditional x-rays, particularly of soft tissues and blood vessels. CT scanning provides more detailed information on head ...

  10. Computed Tomography (CT) -- Head

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    Full Text Available ... sometimes compared to looking into a loaf of bread by cutting the loaf into thin slices. When ... for Brain Tumors Radiation Therapy for Head and Neck Cancer Others American Stroke Association National Stroke Association ...

  11. Early Head Start Evaluation

    Data.gov (United States)

    U.S. Department of Health & Human Services — Longitudinal information from an evaluation where children were randomly assigned to Early Head Start or community services as usual;direct assessments and...

  12. Head Start Impact Study

    Data.gov (United States)

    U.S. Department of Health & Human Services — Nationally representative, longitudinal information from an evaluation where children were randomly assigned to Head Start or community services as usual;direct...

  13. Head CT scan

    Science.gov (United States)

    ... be: Stored Viewed on a monitor Printed on film Three-dimensional models of the head area can ... when you have certain other signs or symptoms Hearing loss (in some people) Symptoms of damage to ...

  14. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... and other symptoms of aneurysm, bleeding, stroke and brain tumors. It also helps your doctor to evaluate your ... provides more detailed information on head injuries, stroke , brain tumors and other brain diseases than regular radiographs (x- ...

  15. Head and Neck Cancer

    Science.gov (United States)

    ... increase the risk of head and neck cancer. Environmental or occupational inhalants. Inhaling asbestos, wood dust, paint ... from the American Society of Clinical Oncology. Review dictionary articles to help understand medical phrases and terms ...

  16. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... used to detect: bleeding, brain injury and skull fractures in patients with head injuries. bleeding caused by ... are present in the paranasal sinuses. plan radiation therapy for cancer of the brain or other tissues. ...

  17. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... used to detect: bleeding, brain injury and skull fractures in patients with head injuries. bleeding caused by ... is also performed to: evaluate the extent of bone and soft tissue damage in patients with facial ...

  18. The interaction of plume heads with compositional discontinuities in the Earth's mantle

    Science.gov (United States)

    Manga, Michael; Stone, Howard A.; O'Connell, Richard J.

    1993-01-01

    The effects of compositional discontinuities of density and viscosity in the Earth's mantle on the ascent of mantle plume heads is studied using a boundary integral numerical technique. Three specific problems are considered: (1) a plume head rising away from a deformable interface, (2) a plume head passing through an interface, and (3) a plume head approaching the surface of the Earth. For the case of a plume attached to a free-surface, the calculated time-dependent plume shapesare compared with experimental results. Two principle modes of plume head deformation are observed: plume head elingation or the formation of a cavity inside the plume head. The inferred structure of mantle plumes, namely, a large plume head with a long tail, is characteristic of plumes attached to their source region, and also of buoyant material moving away from an interface and of buoyant material moving through an interface from a high- to low-viscosity region. As a rising plume head approaches the upper mantle, most of the lower mantle will quickly drain from the gap between the plume head and the upper mantle if the plume head enters the upper mantle. If the plume head moves from a high- to low-viscosity region, the plume head becomes significantly elongated and, for the viscosity contrasts thought to exist in the Earth, could extend from the 670 km discontinuity to the surface. Plume heads that are extended owing to a viscosity decrease in the upper mantle have a cylindrical geometry. The dynamic surface topography induced by plume heads is bell-shaped when the top of the plume head is at depths greater than about 0.1 plume head radii. As the plume head approaches the surface and spreads, the dynamic topography becomes plateau-shaped. The largest stresses are produced in the early stages of plume spreading when the plume head is still nearly spherical, and the surface expression of these stresses is likely to be dominated by radial extension. As the plume spreads, compressional

  19. Systematic review and meta-analysis of wound drains after thyroid surgery.

    LENUS (Irish Health Repository)

    Woods, R S R

    2014-04-01

    Drainage after routine thyroid and parathyroid surgery remains controversial. However, there is increasing evidence from a number of randomized clinical trials (RCTs) suggesting no benefit from the use of drains.

  20. Compositional and functional stability of aerobic methane consuming communities in drained and rewetted peat meadows

    NARCIS (Netherlands)

    Krause, Sascha; Niklaus, Pascal A.; Morcillo, Sara Badwan; Meima-Franke, M.; Lüke, Claudia; Reim, Andreas; Bodelier, Paul L.E.

    2015-01-01

    The restoration of peatlands is an important strategy to counteract subsidence and loss of biodiversity. However, responses of important microbial soil processes are poorly understood. We assessed functioning, diversity, and spatial organization of methanotrophic communities in drained and rewetted

  1. Carbon balance of rewetted and drained peat soils used for biomass production: A mesocosm study

    DEFF Research Database (Denmark)

    Karki, Sandhya; Elsgaard, Lars; Kandel, Tanka

    2016-01-01

    Rewetting of drained peatlands has been recommended to reduce CO2 emissions and to restore the carbon sink function of peatlands. Recently, the combination of rewetting and biomass production (paludiculture) has gained interest as a possible land use option in peatlands for obtaining such benefits...... of lower CO2 emissions without losing agricultural land. The present study quantified the carbon balance (CO2, CH4 and harvested biomass C) of rewetted and drained peat soils under intensively managed reed canary grass (RCG) cultivation. Mesocosms were maintained at five different ground water levels (GWL...... closed chamber methods. The average dry biomass yield was significantly lower from rewetted peat soils (12 Mg ha−1) than drained peat soils (15 Mg ha−1). Also, CO2 fluxes of gross primary production (GPP) and ecosystem respiration (ER) from rewetted peat soils were significantly lower than drained peat...

  2. Numerical Simulation of Liquids Draining From a Tank Using OpenFOAM

    Science.gov (United States)

    Sakri, Fadhilah Mohd; Sukri Mat Ali, Mohamed; Zaki Shaikh Salim, Sheikh Ahmad; Muhamad, Sallehuddin

    2017-08-01

    Accurate simulation of liquids draining is a challenging task. It involves two phases flow, i.e. liquid and air. In this study draining a liquid from a cylindrical tank is numerically simulated using OpenFOAM. OpenFOAM is an open source CFD package and it becomes increasingly popular among the academician and also industries. Comparisons with theoretical and results from previous published data confirmed that OpenFOAM is able to simulate the liquids draining very well. This is done using the gas-liquid interface solver available in the standard library of OpenFOAM. Additionally, this study was also able to explain the physics flow of the draining tank.

  3. Drain-Site Hernia Containing the Vermiform Appendix: Report of a Case

    Directory of Open Access Journals (Sweden)

    Markus Gass

    2013-01-01

    Full Text Available The herniated vermiform appendix has been described as content of every hernia orifice in the right lower quadrant. While the femoral and inguinal herniated vermiform appendix is frequent enough to result in an own designation, port-site or even drain-site hernias are less frequently described. We report the case of a 62-year-old woman who presented with right lower quadrant pain seven years after Roux-en-Y Cystojejunostomy for a pancreatic cyst. CT scan showed herniation of the vermiform appendix through a former drain-site. A diagnostic laparoscopy with appendectomy and direct closure of the abdominal wall defect combined with mesh reinforcement was performed. Despite the decreasing use of intraperitoneal drains over the recent years, a multitude of patients had intraperitoneal drainage in former times. These patients face nowadays the risk of drain-site hernias with sometimes even unexpected structures inside.

  4. Evaluating Use of Sub-Grade Drains with PFC for Stormwater Drainage : final report.

    Science.gov (United States)

    2017-08-01

    The overarching objective of this project is to evaluate the effectiveness of incorporated subgrade drain (usually called underdrain) in the permeable friction course (PFC) pavement to facilitate drainage of stormwater within and on the pavemen...

  5. Media filter drain : modified design evaluation and existing design longevity evaluation.

    Science.gov (United States)

    2014-02-01

    The media filter drain (MFD), a stormwater water quality treatment best management practice, consists of media made up of : aggregate, perlite, gypsum and dolomite in a trench located along roadway shoulders with gravel and vegetative pre-filtering :...

  6. The Role of CorrugateDrain In Decreasing Postoperative Complication Of Penile Fracture Surgery

    Directory of Open Access Journals (Sweden)

    Salam Abd El-Ameer Almosawi

    2017-12-01

    Full Text Available Objective:tostudy the role of corrugate drain (which is used by some urosurgeons followed surgical correction of fractured penis in decreasing post operative complications such as penile swelling, pain and curvature. Patient and method:comparative cross sectional study was carried out at the urological department of Al-Hilla teaching hospital from March 2008 to April 2011. Twenty male patients (age between 21-40 years admitted to the urological department in Al-Hila teaching hospital suffering from penile fracture from March 2008 to April 2011 were included in this study. Immediate surgical repair done to all those patients ,corrugate drain put post operatively for 10 patients while the remaining 10 patients without drains. All patients are fallowed for at least 3 months regarding postoperative penile swelling, deformity, pain and sexual function. Result:regarding age distribution of patients suffering from fracture penis, from twenty patients included in this study 11 patients their agerange from (20-30years, 7 patients their age group range from (31-45years and only 2 patients their age range from (46-60years. Fifteen patients are married and only 5 patients are unmarried. No one develop postoperative penile swelling in patients with corrugate drain and only one patient develops swelling in patients without corrugate drain. Regarding postoperative pain, in patients surgically corrected with drain, 6 patients develop pain and only 2 patients surgically corrected without drain develops pain. Conclusion:No beneficial effect of corrugate drain in decreasing postoperative penile swelling or curvature and on the other hand it increase post operative penile pain.

  7. The Role of CorrugateDrain In Decreasing Postoperative Complication Of Penile Fracture Surgery

    Directory of Open Access Journals (Sweden)

    Salam Abd El-Ameer Almosawi

    2017-12-01

    Full Text Available Objective:tostudy the role of corrugate drain (which is used by some urosurgeons followed surgical correction of fractured penis in decreasing post operative complications such as penile swelling, pain and curvature. Patient and method:comparative cross sectional study was carried out at the urological department of Al-Hilla teaching hospital from March 2008 to April 2011. Twenty male patients (age between 21-40 years admitted to the urological department in Al-Hila teaching hospital suffering from penile fracture from March 2008 to April 2011 were included in this study. Immediate surgical repair done to all those patients ,corrugate drain put post operatively for 10 patients while the remaining 10 patients without drains. All patients are fallowed for at least 3 months regarding postoperative penile swelling, deformity, pain and sexual function. Result:regarding age distribution of patients suffering from fracture penis, from twenty patients included in this study 11 patients their agerange from (20-30years, 7 patients their age group range from (31-45years and only 2 patients their age range from (46-60years. Fifteen patients are married and only 5 patients are unmarried. No one develop postoperative penile swelling in patients with corrugate drain and only one patient develops swelling in patients without corrugate drain. Regarding postoperative pain, in patients surgically corrected with drain, 6 patients develop pain and only 2 patients surgically corrected without drain develops pain. Conclusion:No beneficial effect of corrugate drain in decreasing postoperative penile swelling or curvature and on the other hand it increase post operative penile pain

  8. Suction Drain Tip Culture after Spine Surgery: Can It Predict a Surgical Site Infection?

    OpenAIRE

    Ahn, Jae-Sung; Lee, Ho-Jin; Park, Eugene; Park, Il-Young; Lee, Jae Won

    2015-01-01

    Study Design Retrospective clinical study. Purpose To assess the diagnostic value of suction drain tip culture in patients undergoing primary posterior spine surgery. Overview of Literature To date, the diagnostic value of suction drain tip culture for predicting surgical site infection (SSI) has not been firmly established in orthopedic or spinal surgery. Methods In total, 133 patients who underwent primary posterior spine surgery from January 2013 to April 2015 were included in this retrosp...

  9. Highway filter drain waste arisings: a challenge for urban source control management?

    Science.gov (United States)

    Ellis, J B; Rowlands, E G

    2007-01-01

    Essential maintenance activities on highway BMP drainage controls involve refurbishment of filter (French) drains which can generate substantial amounts of "controlled waste". An innovative procedure for their re-instatement is described which offers a more sustainable option for filter drain/trench management. The quality classification of these waste arisings is problematical and it is difficult to reliably identify the risks posed by such materials and the most effective forms of management and disposal options.

  10. Measurement and analysis of source/drain contact resistance in FinFETs

    Science.gov (United States)

    Dixit, Abhisek; Collaert, Nadine; Jurczak, Malgorzata

    2012-10-01

    FinFET is a key device architecture for the 22-nm CMOS and beyond technology nodes. If special care is not taken, these devices could suffer from high series resistance due to the narrow width of their source/drain regions. Using the electrical characterization of fabricated devices, we extract and analyze the dominant component of this series resistance, namely the source/drain contact resistance.

  11. Human capital in European peripheral regions: brain - drain and brain - gain

    OpenAIRE

    Coenen, Franciscus H.J.M.

    2004-01-01

    Project goal - The overall goal of the project is to build a legitimate transnational network to transfer ideas and experiences and implement measures to reduce brain drain and foster brain gain while reinforcing the economical and spatial development of peripheral regions in NWE. This means a higher quality of life for the inhabitants of these regions combined with a healthy environment. To reach this goal, the project group will study the effects of brain drain/brain gain, co-ordinate appro...

  12. Superior epigastric artery pseudoaneurysm- a rare complication of chest drain insertion in coronary artery bypass grafting

    Directory of Open Access Journals (Sweden)

    Ward Nick

    2007-04-01

    Full Text Available Abstract Background Although chest drain insertion during coronary artery bypass grafting is a fairly standard procedure, however it may result in extremely rare complications. Case presentation This is the first case being reported that demonstrates a pseudoaneurysm of superior epigastric artery resulting from chest drain insertion following coronary artery bypass grafting. Conclusion Adequate caution should be used along with good understanding of the anatomical landmarks during apparently simple and standard operative procedures.

  13. The relationship between drained angle and flow rate of size fractions of powder excipients.

    Science.gov (United States)

    Sklubalová, Z; Zatloukal, Z

    2009-12-01

    The influence of powder size of chosen pharmaceutical powder excipients on drained angle as well as the correlation between drained angle and the mass flow rate of certain powder size fractions were investigated in this work. A method of the indirect estimation of the three-dimensional drained angle from the mass of the residual powder was used experimentally to study the influence of powder size fractions in range of 0.200-0.630 mm for sodium chloride, sodium citrate, potassium chloride, and potassium citrate. Failures of flow significantly increased the drained angles for powder size fraction of 0.200-0.250 mm. For the uniformly flowable powder size fraction of 0.400-0.500 mm, the faster the flow rate, the smaller drained angles were observed for excipients investigated. To estimate parameters of the flow equation, the measurement of material flow rates from the hopper of different orifice sizes is needed, while the estimation of drained angle is much easier needing only one hopper. Finally, the increase of the hopper wall angle of the standard conical hopper to 70 degrees could be recommended to achieve uniform mass flow and to reduce the adverse effect of powder gliding along the hopper walls.

  14. Laparoscopic retrieval of retained intraperitoneal drain in the immediate postoperative period Report of two cases.

    Science.gov (United States)

    Carlomagno, Nicola; Santangelo, Michele; Grassia, Sebastiano; La Tessa, Cristina; Renda, Andrea

    2012-10-23

    AIM: The purpose of this study is to analyze a "rare" complication on the management of abdominal surgical drains: abdominal drainage's retention. Starting from our experience we reviewed literature on this topic MATERIAL OF STUDY: We report two cases (occurred on 2004 and 2010) of retained intraperitoneal drain occurred in the immediate postoperative period after laparoscopic cholecystectomy. RESULTS: Both patients were successfully treated by early laparoscopic removal. DISCUSSION: We compared our experience with literature. Incidence, ethiology, prevention, diagnosis and treatment of this rare complication are analysed. We also considered the guidelines in the placement of intraperitoneal drains, the different fixation techniques, the causes of fragmentation of the drainage and removal techniques. CONCLUSIONS: Retained intraperitoneal drain secondary to fracture and adhesion in the immediate postoperative period is rare but probably underestimated surgical complication. It is impossible to know its real incidence. The role of laparoscopy is emphasized because this approach is cosmetically acceptable, contributes to early recovery and discharge of the patient, and helps to lessen the friction in worsening doctor-patient relationship. KEY WORDS: Abdominal drainage, Drain-related complications, Laparoscopy, Retained intraperitoneal drain.

  15. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... News Physician Resources Professions Site Index A-Z Magnetic Resonance Imaging (MRI) - Head Magnetic resonance imaging (MRI) of the head ... limitations of MRI of the Head? What is MRI of the Head? Magnetic resonance imaging (MRI) is ...

  16. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... Physician Resources Professions Site Index A-Z Magnetic Resonance Imaging (MRI) - Head Magnetic resonance imaging (MRI) of the head uses a powerful ... Head? What is MRI of the Head? Magnetic resonance imaging (MRI) is a noninvasive medical test that ...

  17. Reverse blocking characteristics and mechanisms in Schottky-drain AlGaN/GaN HEMT with a drain field plate and floating field plates

    Science.gov (United States)

    Wei, Mao; Wei-Bo, She; Cui, Yang; Jin-Feng, Zhang; Xue-Feng, Zheng; Chong, Wang; Yue, Hao

    2016-01-01

    In this paper, a novel AlGaN/GaN HEMT with a Schottky drain and a compound field plate (SD-CFP HEMT) is presented for the purpose of better reverse blocking capability. The compound field plate (CFP) consists of a drain field plate (DFP) and several floating field plates (FFPs). The physical mechanisms of the CFP to improve the reverse breakdown voltage and to modulate the distributions of channel electric field and potential are investigated by two-dimensional numerical simulations with Silvaco-ATLAS. Compared with the HEMT with a Schottky drain (SD HEMT) and the HEMT with a Schottky drain and a DFP (SD-FP HEMT), the superiorities of SD-CFP HEMT lie in the continuous improvement of the reverse breakdown voltage by increasing the number of FFPs and in the same fabrication procedure as the SD-FP HEMT. Two useful optimization laws for the SD-CFP HEMTs are found and extracted from simulation results. The relationship between the number of the FFPs and the reverse breakdown voltage as well as the FP efficiency in SD-CFP HEMTs are discussed. The results in this paper demonstrate a great potential of CFP for enhancing the reverse blocking ability in AlGaN/GaN HEMT and may be of great value and significance in the design and actual manufacture of SD-CFP HEMTs. Project supported by the National Natural Science Foundation of China (Grant Nos. 61204085, 61334002, 61306017, 61474091, 61574112, and 61574110).

  18. Aerobic Heterotrophic Biodégradation in Polluted Drains and Sewers: The drain and sewer as dual-phase biological reactors

    NARCIS (Netherlands)

    Cao, Y.S.

    1994-01-01

    Wastewater collection systems such as sewers, sewage drains, and polluted shallow aquatic systems such as rivers, streams, and lagoons are characterized by the fact that both suspended and attached biomass exist and function. They are dual-phase systems. Contrary to biofilm dominated systems such as

  19. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... it will be swallowed, injected through an intravenous line (IV) or, rarely, administered by enema. Next, the ... When you enter the CT scanner, special light lines may be seen projected onto your body, and ...

  20. Pesticide leaching via subsurface drains in different hydrologic situations

    Science.gov (United States)

    Zajíček, Antonín; Fučík, Petr; Liška, Marek; Dobiáš, Jakub

    2017-04-01

    esticides and their degradates in tile drainage waters were studied in two small, predominantly agricultural, tile-drained subcatchments in the Bohemian-Moravian Highlands, Czech Republic. The goal was to evaluate their occurence and the dymamics of their concentrations in drainage waters in different hydrologic situations using discharge and concentration monitoring together with 18O and 2H isotope analysis for Mean Residence Time (MRT) estimation and hydrograph separations during rainfall - runoff (R-R) events. The drainage and stream discharges were measured continuously at the closing outlets of three drainage groups and one small stream. During periods of prevailing base and interflow, samples were collected manually in two-week intervals for isotope analysis and during the spraying period (March to October) also for pesticide analysis. During R-R events, samples were taken by automatic samplers in intervals varying from 20 min (summer) to 1 hour (winter). To enable isotopic analysis, precipitation was sampled both manually at two-week intervals and also using an automatic rainfall sampler which collected samples of precipitation during the R-R events at 20-min. intervals. The isotopic analysis showed, that MRT of drainage base flow and interflow varies from 2,2 to 3,3 years, while MRT of base flow and interflow in surface stream is several months. During R-R events, the proportion of event water varied from 0 to 60 % in both drainage and surface runoff. The occurrence of pesticides and their degradates in drainage waters is strongly dependent on the hydrologic situation. While degradates were permanently present in drainage waters in high but varying concentrations according to instantaneous runoff composition, parent matters were detected almost exclusively during R-R events. In periods with prevailing base flow and interflow (grab samples), especially ESA forms of chloracetanilide degradates occured in high concentrations in all samples. Average sum of

  1. Forecasting Selenium Discharges to the San Francisco Bay-Delta Estuary: Ecological Effects of A Proposed San Luis Drain Extension

    Science.gov (United States)

    Presser, Theresa S.; Luoma, Samuel N.

    2006-01-01

    , and effects of selenium released to the Bay-Delta through use of (1) historical land-use, drainage, alluvial-fill, and runoff databases; (2) existing knowledge concerning biogeochemical reactions and physiological parameters of selenium (e.g., speciation, partitioning between dissolved and particulate forms, and bivalve assimilation efficiency); and (3) site-specific data mainly from 1986 to 1996 for clams and bottom-feeding fish and birds. Selenium load scenarios consider effluents from North Bay oil refineries and discharges of agricultural drainage from the San Joaquin Valley to enable calculation of (a) a composite freshwater endmember selenium concentration at the head of the estuary; and (b) a selenium concentration at a selected seawater location (Carquinez Strait) as a foundation for modeling. Analysis of selenium effects also takes into account the mode of conveyance for agricultural drainage (i.e., the San Luis Drain or San Joaquin River); and flows of the Sacramento River and San Joaquin River on a seasonal or monthly basis. Load scenarios for San Joaquin Valley mirror predictions made since 1955 of a worsening salt (and by inference, selenium) build-up exacerbated by an arid climate and massive irrigation. The reservoir of selenium in the San Joaquin Valley is sufficient to provide loading at an annual rate of approximately 42,500 pounds of selenium to a Bay-Delta disposal point for 63 to 304 years at the lower range of projections presented here, even if influx of selenium from the California Coast Ranges could be curtailed. Disposal of wastewaters on an annual basis outside of the San Joaquin Valley may slow the degradation of valley resources, but drainage alone cannot alleviate the salt and selenium build-up in the San Joaquin Valley, at least within a century. Load scenarios also show the different proportions of selenium loading to the Bay-Delta. Oil refinery loads from 1986 to 1992 ranged from 8.5 to 20 pounds of selenium per day;

  2. Effect of head model on Monte Carlo modeling of spatial sensitivity distribution for functional near-infrared spectroscopy

    Directory of Open Access Journals (Sweden)

    Ting Li

    2015-09-01

    Full Text Available Modeling Light propagation within human head to deduce spatial sensitivity distribution (SSD is important for Near-infrared spectroscopy (NIRS/imaging (NIRI and diffuse correlation tomography. Lots of head models have been used on this issue, including layered head model, artificial simplified head model, MRI slices described head model, and visible human head model. Hereinto, visible Chinese human (VCH head model is considered to be a most faithful presentation of anatomical structure, and has been highlighted to be employed in modeling light propagation. However, it is not practical for all researchers to use VCH head models and actually increasing number of people are using magnet resonance imaging (MRI head models. Here, all the above head models were simulated and compared, and we focused on the effect of using different head models on predictions of SSD. Our results were in line with the previous reports on the effect of cerebral cortex folding geometry. Moreover, the influence on SSD increases with the fidelity of head models. And surprisingly, the SSD percentages in scalp and gray matter (region of interest in MRI head model were found to be 80% and 125% higher than in VCH head model. MRI head models induced nonignorable discrepancy in SSD estimation when compared with VCH head model. This study, as we believe, is the first to focus on comparison among full serials of head model on estimating SSD, and provided quantitative evidence for MRI head model users to calibrate their SSD estimation.

  3. Pediatric head injury.

    Science.gov (United States)

    Tulipan, N

    1998-01-01

    Pediatric head injury is a public health problem that exacts a high price from patients, their families and society alike. While much of the brain damage in head-injured patients occurs at the moment of impact, secondary injuries can be prevented by aggressive medical and surgical intervention. Modern imaging devices have simplified the task of diagnosing intracranial injuries. Recent advances in monitoring technology have made it easier to assess the effectiveness of medical therapy. These include intracranial pressure monitoring devices that are accurate and safe, and jugular bulb monitoring which provides a continuous, qualitative measure of cerebral blood flow. The cornerstones of treatment remain hyperventilation and osmotherapy. Despite maximal treatment, however, the mortality and morbidity associated with pediatric head injury remains high. Reduction of this mortality and morbidity will likely depend upon prevention rather than treatment.

  4. Management Controversies in Head and Neck Melanoma: A Systematic Review.

    Science.gov (United States)

    Zenga, Joseph; Nussenbaum, Brian; Cornelius, Lynn A; Linette, Gerald P; Desai, Shaun C

    2017-01-01

    Head and neck melanoma is one of the leading causes of death in the United States and is currently increasing in prevalence. While there is a tremendous amount of research published on melanoma, the actual evidence for complex clinical decision-making can be difficult to interpret and to stay up-to-date on current clinical standards. To address, in a systematic and evidence-based approach, the most common clinical controversies with regard to the workup and management of head and neck melanoma. A PubMed and Medline search was performed of the entire English literature with respect to head and neck melanoma. Priority of review was given to those studies with higher-quality levels of evidence. Main topics reviewed in this article include workup for new melanoma, surgical treatment of the primary site, surgical treatment of the neck, adjuvant radiation therapy, and systemic therapy. Levels of evidence are used for each controversial clinical question to help the clinician understand the reliability of the current evidence when making complex clinical decisions for melanoma management of the head and neck. However, much of the work done in melanoma, particularly large randomized clinical trials, includes many other regions of the body. Therefore, these data must be interpreted in light of the potential differences in clinical behavior and draining lymphatics between trunk, limbs, and head and neck subsites. The management of head and neck melanoma requires a multidisciplinary approach, particularly for advanced-stage disease. An in-depth knowledge of the current evidence available will help guide the surgeon in the management of this difficult disease.

  5. Hydra multiple head star sensor and its in-flight self-calibration of optical heads alignment

    Science.gov (United States)

    Majewski, L.; Blarre, L.; Perrimon, N.; Kocher, Y.; Martinez, P. E.; Dussy, S.

    2017-11-01

    HYDRA is EADS SODERN new product line of APS-based autonomous star trackers. The baseline is a multiple head sensor made of three separated optical heads and one electronic unit. Actually the concept which was chosen offers more than three single-head star trackers working independently. Since HYDRA merges all fields of view the result is a more accurate, more robust and completely autonomous multiple-head sensor, releasing the AOCS from the need to manage the outputs of independent single-head star trackers. Specific to the multiple head architecture and the underlying data fusion, is the calibration of the relative alignments between the sensor optical heads. The performance of the sensor is related to its estimation of such alignments. HYDRA design is first reminded in this paper along with simplification it can bring at system level (AOCS). Then self-calibration of optical heads alignment is highlighted through descriptions and simulation results, thus demonstrating the performances of a key part of HYDRA multiple-head concept.

  6. Texturing of Surface of 3D Human Head Model

    Directory of Open Access Journals (Sweden)

    V. Michalcin

    2004-12-01

    Full Text Available The paper deals with an algorithm of texturing of the surface of 3Dhuman head model. The proposed algorithm generates a textureconsequently of several camera frames of the input video sequence. Thetexture values from the camera frames are mapped on the surface of the3D human head model using perspective projection, scan line and 3Dmotion estimation. To decrease the number of camera frames a filling ofempty places by a simple interpolation method has been done in thetexture plane.

  7. Radiation dose associated with CT-guided drain placement for pediatric patients

    Energy Technology Data Exchange (ETDEWEB)

    Schwartz, Cody J.; Isaacson, Ari J.; Fordham, Lynn Ansley; Ivanovic, Marija; Dixon, Robert G. [University of North Carolina at Chapel Hill, Department of Radiology, UNC Health Care, Chapel Hill, NC (United States); Taylor, J.B. [University of North Carolina at Chapel Hill, Environment, Health and Safety, Chapel Hill, NC (United States)

    2017-05-15

    To date, there are limited radiation dose data on CT-guided procedures in pediatric patients. Our goal was to quantify the radiation dose associated with pediatric CT-guided drain placement and follow-up drain evaluations in order to estimate effective dose. We searched the electronic medical record and picture archiving and communication system (PACS) to identify all pediatric (<18 years old) CT-guided drain placements performed between January 2008 and December 2013 at our institution. We compiled patient data and radiation dose information from CT-guided drain placements as well as pre-procedural diagnostic CTs and post-procedural follow-up fluoroscopic abscess catheter injections (sinograms). Then we converted dose-length product, fluoroscopy time and number of acquisitions to effective doses using Monte Carlo simulations and age-appropriate conversion factors based on annual quality-control testing. Fifty-two drainages were identified with mean patient age of 11.0 years (5 weeks to 17 years). Most children had diagnoses of appendicitis (n=23) or inflammatory bowel disease (n=11). Forty-seven patients had diagnostic CTs, with a mean effective dose of 7.3 mSv (range 1.1-25.5 mSv). Drains remained in place for an average of 16.9 days (range 0-75 days), with an average of 0.9 (0-5) sinograms per patient in follow-up. The mean effective dose for all drainages and follow-up exams was 5.3 mSv (0.7-17.1) and 62% (32/52) of the children had effective doses less than 5 mSv. The majority of pediatric patients who have undergone CT-guided drain placements at our institution have received total radiation doses on par with diagnostic ranges. This information could be useful when describing the dose of radiation to parents and providers when CT-guided drain placement is necessary. (orig.)

  8. Pancreatoduodenectomy: role of drain fluid analysis in the management of pancreatic fistula.

    Science.gov (United States)

    Kong, Justin; Gananadha, Sivakumar; Hugh, Thomas J; Samra, Jaswinder S

    2008-04-01

    Pancreatic fistula remains an important cause of death following pancreatoduodenectomy. There is still uncertainty regarding the use of drains following pancreatoduodenectomy with recent reports suggesting that it might be harmful with increased complications. We evaluated the use of drain fluid analysis in the management of patients following pancreatoduodenectomy. A prospective study was conducted on all patients undergoing pancreatoduodenectomy at two hospitals between April 2004 and August 2006. Drain fluid analysis was carried out from day 3 to day 5. These data were collected with the clinical pictures of the patients and with subsequent radiological assessment. Fifty consecutive patients underwent modified extended pancreatoduodenectomy for a periampullary tumour. In patients with no clinical evidence of a fistula, the mean postoperative drain fluid amylase levels were as follows: on postoperative day 3 it was 262 U/mL (standard error of mean 69), on postoperative day 4 it was 112 U/mL (standard error of mean 47) and on postoperative day 5 it was 125 U/mL (standard error of mean 64). Only three (6/6, 50%) of these patients had clinical features suggestive of a leak and were found to have a pancreatic fistula on subsequent imaging. There was no correlation between the total or mean volumes of drainage and development of a pancreatic fistula. The drain fluid analysis did not provide additional information that was not already evident from the clinical picture of the patient. Drain fluid analysis had no effect on patients with a biochemical leak only. Patients who had a significant disruption of their pancreatic anastamosis did not need biochemical analysis as the character, that is, turbidity of the drain fluid was an equally reliable indicator of the underlying pathology.

  9. Head First Statistics

    CERN Document Server

    Griffiths, Dawn

    2009-01-01

    Wouldn't it be great if there were a statistics book that made histograms, probability distributions, and chi square analysis more enjoyable than going to the dentist? Head First Statistics brings this typically dry subject to life, teaching you everything you want and need to know about statistics through engaging, interactive, and thought-provoking material, full of puzzles, stories, quizzes, visual aids, and real-world examples. Whether you're a student, a professional, or just curious about statistical analysis, Head First's brain-friendly formula helps you get a firm grasp of statistics

  10. Head and Neck Reconstruction.

    Science.gov (United States)

    Wong, Shannon; Melin, Alyson; Reilly, Debra

    2017-10-01

    Management of head and neck burns involves acute and intermediate phases. Acutely, the goals are establish a secure airway and treat life-threatening injuries. Then, optimize nutrition, assess extent of the burn, perform local wound care, and provide eye protection. Management depends on the degree of the head and neck burn. Postinjury splinting and rehabilitation are vital to healing. After the acute inflammation has resolved and the scars have matured, reconstruction begins with the goals of restoring both function and aesthetics. Reconstruction ranges from simple scar release, to skin grafting, and possibly free flap reconstruction. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. Head first Ajax

    CERN Document Server

    Riordan, Rebecca M

    2008-01-01

    Ajax is no longer an experimental approach to website development, but the key to building browser-based applications that form the cornerstone of Web 2.0. Head First Ajax gives you an up-to-date perspective that lets you see exactly what you can do -- and has been done -- with Ajax. With it, you get a highly practical, in-depth, and mature view of what is now a mature development approach. Using the unique and highly effective visual format that has turned Head First titles into runaway bestsellers, this book offers a big picture overview to introduce Ajax, and then explores the use of ind

  12. On the extraction of the external drain and source resistors and effective channel length in Si-MOSFET

    Science.gov (United States)

    Joodaki, M.

    2015-09-01

    This paper focuses on the extraction of drain/source resistance and effective channel length (Leff) of the silicon MOSFET in the linear drain current region. Leff is expressed as a function of drain/source resistance, drain current, threshold voltage, drain voltage, and body-effect coefficient. Using this definition, an additional component of drain/source resistance in the linear drain current region, inversion charge reduction resistance (RΔQ), is introduced which results from the influence of drain/source resistors, internal source/body voltage and drain voltage on the total inversion charge. Finally, a new method for extraction of the drain/source resistance is developed. In this method several parameters that have impact on device behavior are considered. The parameters include gate voltage dependency, short channel effects, and poly gate length dependency. The results presented here are not only very useful for accurate device modeling and characterization, but are also vital to better understanding of the device physics. Furthermore, they can describe shortcomings of the other methods which use devices of different gate lengths. The extracted linear model provides less than 1.07% and 3.3% average absolute error and maximum error, respectively, for all seven devices under test over the gate voltage range of 0.75-2 V.

  13. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available Toggle navigation Test/Treatment Patient Type Screening/Wellness Disease/Condition Safety En Español More Info Images/Videos ... head injuries, stroke , brain tumors and other brain diseases than regular radiographs (x-rays). top of page ...

  14. Lubricating the swordfish head

    NARCIS (Netherlands)

    Videler, John J.; Haydar, Deniz; Snoek, Roelant; Hoving, Henk-Jan T.; Szabo, Ben G.

    The swordfish is reputedly the fastest swimmer on Earth. The concave head and iconic sword are unique characteristics, but how they contribute to its speed is still unknown. Recent computed tomography scans revealed a poorly mineralised area near the base of the rostrum. Here we report, using

  15. Waco Head Start Program.

    Science.gov (United States)

    Porter, Para

    The Economic Opportunity Act of 1964 led to the formation of three separate Head Start Programs in Waco, Texas. The first year, 1,500 children were involved. Of these, 40 percent were Negro, 30 percent Latin American, and 30 percent white. All teachers received a week of preparatory study at the University of Texas. The program involved four areas…

  16. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available Toggle navigation Test/Treatment Patient Type Screening/Wellness Disease/Condition Safety En Español More Info Images/Videos About Us News Physician Resources Professions Site Index A-Z Computed Tomography (CT) - Head ...

  17. Ultrasound: Head (For Parents)

    Science.gov (United States)

    ... a safe and painless test that uses sound waves to make images of the brain. During the examination, an ultrasound machine sends sound ... The fontanel provides an opening for the sound waves to get through and reach the brain. Why It's Done Doctors order head ultrasounds when ...

  18. Silva as the Head

    DEFF Research Database (Denmark)

    Svabo, Connie

    2015-01-01

    The head of the performance design programme is substituted by a sister's academy delegate. this performance situation formed part of a week of semesterstart where the students and professors visited Sister's Academy, Malmø. I participated in the Sister's Academy as visiting researcher and here...

  19. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... full size with caption Pediatric Content Some imaging tests and treatments have special pediatric considerations. The teddy bear denotes child-specific content. Related Articles and Media Radiation Dose in X-Ray and CT Exams Blood Clots CT Perfusion of the Head CT Angiography ( ...

  20. Outbreak of severe Pseudomonas aeruginosa infections caused by a contaminated drain in a whirlpool bathtub.

    Science.gov (United States)

    Berrouane, Y F; McNutt, L A; Buschelman, B J; Rhomberg, P R; Sanford, M D; Hollis, R J; Pfaller, M A; Herwaldt, L A

    2000-12-01

    During a 14-month period, 7 patients with hematological malignancies acquired serious infections caused by a single strain of multiply resistant Pseudomonas aeruginosa. A case-control study, culture surveys, and pulsed-field gel electrophoresis implicated a whirlpool bathtub on the unit as the reservoir. All case patients and 32% of control patients used this bathtub (P=.003). The epidemic strain was found only in cultures of samples taken from the bathtub. The drain of the whirlpool bathtub, which was contaminated with the epidemic strain, closed approximately 2.54 cm below the drain's strainer. Water from the faucet, which was not contaminated, became contaminated with P. aeruginosa from the drain when the tub was filled. The design of the drain allowed the epidemic strain to be transmitted to immunocompromised patients who used the whirlpool bathtub. Such tubs are used in many hospitals, and they may be an unrecognized source of nosocomial infections. This potential source of infection could be eliminated by using whirlpool bathtubs with drains that seal at the top.

  1. Effect of tunnel length on infection rate in patients with external ventricular drain.

    Science.gov (United States)

    Rafiq, Mirza Faisal Ahmed; Ahmed, Noor; Ali, Shafqut

    2011-01-01

    External ventricular drain involves catheter placement in ventricles of brain. It is used for various purposes. Basic theme is to drain cerebrospinal fluid so as to control intracranial pressure. This study was carried out to see the effect of tunnel length on rate of infection. This was a cross-sectional study carried out in Department of Neurosurgery, Pakistan Institute of Medical Sciences, Islamabad during 14 months from 1st December 2008 to 31 January 2010. External ventricular drain was placed in admitted patients after meticulous aseptic technique in operation theatre at right Kocher's point. It was carried out through a scalp tunnel and was connected to drainage bag through a drip set. Both long (> 5 Cm) and short (drain). All patients received prophylactic Ceftriaxone. Among 76 patients long tunnel was made in 44 (57.9%) and short in 32 (42.1%). Three patients (3.9%) with long tunnel while 6 (7.9%) patients with short tunnel had infection. The overall infection was in 9 (11.8%) patients. External ventricular drain tunnel length strongly influences the rate of infection.

  2. Stemming the Impact of Health Professional Brain Drain from Africa: A Systemic Review of Policy Options.

    Science.gov (United States)

    Zimbudzi, Edward

    2013-06-25

    Africa has been losing professionally trained health workers who are the core of the health system of this continent for many years. Faced with an increased burden of disease and coupled by a massive exodus of the health workforce, the health systems of many African nations are risking complete paralysis. Several studies have suggested policy options to reduce brain drain from Africa. The purpose of this paper is to review possible policies, which can stem the impact of health professional brain drain from Africa. A systemic literature review was conducted. Cinahl, Science Direct and PubMed databases were searched with the following terms: health professional brain drain from Africa and policies for reducing impact of brain drain from Africa. References were also browsed for relevant articles. A total of 425 articles were available for the study but only 23 articles met the inclusion criteria. The review identified nine policy options, which were being implemented in Africa, but the most common was task shifting which had success in several African countries. This review has demonstrated that there is considerable consensus on task shifting as the most appropriate and sustainable policy option for reducing the impact of health professional brain drain from Africa.

  3. Stemming the impact of health professional brain drain from Africa: a systemic review of policy options

    Directory of Open Access Journals (Sweden)

    Edward Zimbudzi

    2013-06-01

    Full Text Available Africa has been losing professionally trained health workers who are the core of the health system of this continent for many years. Faced with an increased burden of disease and coupled by a massive exodus of the health workforce, the health systems of many African nations are risking complete paralysis. Several studies have suggested policy options to reduce brain drain from Africa. The purpose of this paper is to review possible policies, which can stem the impact of health professional brain drain from Africa. A systemic literature review was conducted. Cinahl, Science Direct and PubMed databases were searched with the following terms: health professional brain drain from Africa and policies for reducing impact of brain drain from Africa. References were also browsed for relevant articles. A total of 425 articles were available for the study but only 23 articles met the inclusion criteria. The review identified nine policy options, which were being implemented in Africa, but the most common was task shifting which had success in several African countries. This review has demonstrated that there is considerable consensus on task shifting as the most appropriate and sustainable policy option for reducing the impact of health professional brain drain from Africa.

  4. Sensitivity of carbon gas fluxes to weather variability on pristine, drained and rewetted temperate bogs

    Directory of Open Access Journals (Sweden)

    Z. Urbanová

    2013-05-01

    Full Text Available Climate change is considered to alter the functioning of boreal peatland ecosystems, but the vulnerability of pristine, rewetted and drained peatlands to climate change in temperate regions is unknown. We measured carbon (C gas exchange during wet (2009 and dry (2010 growing periods in pristine, drained and rewetted sites in mountain bogs in the Bohemian Forest (Czech Republic. Wetter lawns with sedges and drier habitats dominated by ericaceous shrubs were distinguished and studied at each site. Methane (CH4 emissions, which decreased in the order pristine > rewetted > drained, were generally lower during the 2010 growing period than in 2009 as a consequence of a drought. During the drought in 2010, photosynthesis (PG in the drier habitats with shrub vegetation increased on pristine and rewetted sites, while total respiration (RECO remained the same. Communities dominated by sedges maintained similar rates of PG and RECO during both growing periods. Generally, this led to higher C accumulation during the drought on pristine and rewetted bogs. At the drained bog site, the decreased water table (WT during the drought led to increased PG and RECO, such that the net C accumulation was similar in the two years. Drained peatlands may be more threatened by future climate change than pristine or rewetted peatlands because of their limited buffering capacity for decreased WT. In the case of further decreases in WT, they could lose the peatland vegetation and functions that have partly persisted through decades of drainage.

  5. Contribution of household herbicide usage to glyphosate and its degradate aminomethylphosphonic acid in surface water drains.

    Science.gov (United States)

    Ramwell, Carmel T; Kah, Melanie; Johnson, Paul D

    2014-12-01

    It is necessary to understand the extent to which different sources of pesticides contribute to surface water contamination in order to focus preventive measures appropriately. The extent to which glyphosate use in the home and garden sector may contribute to surface water contamination has not previously been quantified. The aim of this study was to quantify the widely used herbicide glyphosate and its degradation product aminomethylphosphonic acid (AMPA) in surface water drains (storm drains) that could be attributed to amateur, non-professional usage alone. Maximum glyphosate and AMPA concentrations in surface water drains were 8.99 and 1.15 µg L(-1) respectively after the first rain event following the main application period, but concentrations rapidly declined to <1.5 and <0.5 µg L(-1) . The AMPA:glyphosate ratio was typically 0.35. Less than 1% of the applied glyphosate was recovered in drain water. Glyphosate and AMPA losses from urban areas that arise solely from amateur usage have been quantified. In spite of overdosing occurring, glyphosate concentrations in drain flow were lower than concentrations reported elsewhere from professional use in urban areas. © 2014 Society of Chemical Industry.

  6. [Risk of ventriculitis associated to the care of the ventricular drain in neurocritical patients].

    Science.gov (United States)

    Rivas-Rodriguez, Aida; Suarez-Mier, Belén; Rivas-Rodriguez, Lidia; Lana, Alberto

    2016-04-16

    To analyze the risk of ventriculitis associated to the care of the external ventricular drain. Case-control study among a sample of neurocritical patients of the University Hospital of Asturias (Spain) who carried a ventricular catheter (n = 127; 49 cases and 78 controls). Main outcome was the diagnosis of ventriculitus, according to established criteria. Independent variables were related to the catheter management, including nursing cares of the insertion point, administration of intrathecal medication, flushes, changes and mobilization of the catheter. Other variables (age, sex, APACHE score, admission diagnosis, comorbidity, antibiotics, time to insertion and permanence time of the drain) were studied as covariates. Nursing catheter cares (OR 3.8; 95% CI: 1.1-13.9) and administration of intrathecal medication (OR: 7.1; 95% CI: 2.1-23.6) were significantly associated with ventriculitis. After adjustment by the number of days at risk, the effect of nursing cares disappeared (OR 1.4; 95% CI: 0.3-6.6). Intrathecal medication and nursing cares seem to be associated with ventriculitis. The administration of medication by the ventricular drain really reflects that the physicians suspect ventriculitis before the diagnosis is confirmed and, therefore, they prescribe this medication. However, as the duration of drain increases the frequency of nursing cares, it seems prudent to recommend not lengthen the permanence of the ventricular drain and to improve the training of nurses.

  7. Effects of Source and Drain Resistances on Analytical Model Parameters for 20nm MOSFETs

    Science.gov (United States)

    Yoon, Jong Chul; Nakade, Yasunari; Hiroki, Akira; Inoue, Fumitaka; Tomiyama, Kenji

    In this work, the effects of source and drain resistances (RS, RD) on device characteristics are investigated for sub-20nm MOSFETs. The current driving capability is calculated for several structures such as planar bulk, SOI, and Multi gate MOSFETs by using the ITRS data. It is found that the degradation of the drain currents due to RS and RD becomes significant as the gate lengths are scale down to sub-20nm region. In order to investigate the effects of RS and RD on the device parameters such as the channel length modulation coefficient λ and the saturation drain current IDSAT, the drain currents are simulated by using the circuit simulation. The intrinsic MOSFET model parameters were extracted from the experimental ID-VD characteristic of 20nm nMOSFET. The source and drain resistances are changed from 0 to 100 ohm. It is found that the degradation of IDSAT due to RS and RD shows the linear gate voltage dependence. For the long channel MOSFET, the degradation of λ shows the linear gate voltage dependence. On the contrary, for the short channel MOSFET, the degradation of λ shows the little gate voltage dependence.

  8. Head nurses as middle managers.

    Science.gov (United States)

    Johnston, P F

    1983-11-01

    The relationship between head nurses and their staff nurses influences staff turnover rates and job satisfaction. In this article the author describes the measures taken by the management of Greater Southeast Community Hospital in response to an increasing turnover rate among staff RNs. In recognition of the head nurse role vis-d-vis attrition rates and job satisfaction, head nurses were upgraded to department head status and rigorous head nurse performance standards were developed. These standards required clinical expertise, managerial competence, and accountability. It is the author's contention that clinical practice and staff morale are directly related to a clearly defined head nurse role.

  9. Head Tilting Elicited by Head Turning in Three Dogs with Hypoplastic Cerebellar Nodulus and Ventral Uvula

    Directory of Open Access Journals (Sweden)

    Shinji Tamura

    2016-11-01

    Full Text Available The nodulus and ventral uvula (NU of the cerebellum play a major role in vestibular function in humans and experimental animals; however, there is almost no information about NU function in the veterinary clinical literature. In this report, we describe three canine cases diagnosed with presumptive NU hypoplasia. Of them, one adult dog presented with cervical intervertebral disk disease, and two juvenile dogs presented with signs of central vestibular disease. Interestingly, an unusual and possibly overlooked neurological sign that we called positioning head tilt was observed in these dogs. The dogs were able to turn freely in any direction at will. The head was in a level position when static or when the dog walked in a straight line. However, the head was tilted to the opposite side when the dog turned. Veterinary clinicians should be aware of this neurological sign, which has not been reported previously, and its application in lesion localization in dogs.

  10. Head injuries, heading, and the use of headgear in soccer.

    Science.gov (United States)

    Niedfeldt, Mark W

    2011-01-01

    Soccer has more than 265 million players around the world and is the only contact sport with purposeful use of the head for controlling and advancing the ball. Head contact in soccer has the potential to cause acute traumatic brain injury including concussion or, potentially, a pattern of chronic brain injury. Although early retrospective research on the effects of soccer heading seemed to suggest that purposeful heading may contribute to long-term cognitive impairment, prospective controlled studies do not support this and, in fact, suggest that purposeful heading may not be a risk factor for cognitive impairment. Headgear has not been shown to be effective in reducing ball impact but may be helpful in reducing the force of non-ball-related impacts to the head. There are concerns that universal use of headgear may cause more aggressive heading and head challenges, leading to increased risk of injury.

  11. Postoperative use of drain in thyroid lobectomy – a randomized clinical trial conducted at Civil Hospital, Karachi, Pakistan

    Directory of Open Access Journals (Sweden)

    Memon Zahid

    2012-09-01

    Full Text Available Abstract Background Thyroidectomy is a common surgical procedure, after which drains are placed routinely. This study aims to assess the benefits of placing postoperative drains, its complications and affects on postoperative stay, in thyroid lobectomy. Methodology Randomized Clinical Trial of 60 goitre patients undergoing lobectomy was conducted at Civil Hospital Karachi, during July’11-December’11. Patients were randomly assigned into drain and non drain groups. Patient demographics, labs and complications were noted. Ultrasound of neck was performed on both groups. For drain group, the amount of fluid present in the surgical bed and redivac drain was added to calculate fluid collection while in non drain group it was calculated by ultrasound of neck on first and second post-op days. Data was entered and analyzed on SPSS v16 using Independent T tests. Result The mean total drain output for 2 days in non-drain group was significantly lower 10.67 (±9.072 ml while in drain group was 30.97 (±42.812 ml (p = 0.014. The mean postoperative stay of drain group (79.2 ±15.63 hours was significantly higher, as compared to mean postoperative stay of non drain group (50.4 ±7.32 hours. Mean Visual Analogue Score (VAS for pain day 1 (6.2 ±0.997 and day 2 (4.17 ±0.95 in drain group were significantly higher compared to day 1 (2.6 ±1.163 and day 2 (1.3 ±0.877 of non drain group. From drain group, 2 patients complained of stridor, dyspnea on Day 1 which subsided by Day 2 and 1 case of voice change, with no such complains in non drain group. No patients from both groups developed seroma, wound infection or hematoma. Conclusion In uncomplicated surgeries especially for lobectomy, use of drain can be omitted.

  12. Radial Head Fractures

    Science.gov (United States)

    Jordan, Robert W.; Jones, Alistair DR.

    2017-01-01

    Background: Radial head fractures are common elbow injuries in adults and are frequently associated with additional soft tissue and bone injuries. Methods: A literature search was performed and the authors’ personal experiences are reported. Results: Mason type I fractures are treated non-operatively with splinting and early mobilisation. The management of Mason type II injuries is less clear with evidence supporting both non-operative treatment and internal fixation. The degree of intra-articular displacement and angulation acceptable for non-operative management has yet to be conclusively defined. Similarly the treatment of type III and IV fractures remain controversial. Traditional radial head excision is associated with valgus instability and should be considered only for patients with low functional demands. Comparative studies have shown improved results from internal fixation over excision. Internal fixation should only be attempted when anatomic reduction and initiation of early motion can be achieved. Authors have reported that results from fixation are poorer and complication rates are higher if more than three fragments are present. Radial head arthroplasty aims to reconstruct the native head and is indicated when internal fixation is not feasible and in the presence of complex elbow injuries. Overstuffing of the radiocapitellar joint is a frequent technical fault and has significant adverse effects on elbow biomechanics. Modular design improves the surgeon’s ability to reconstruct the native joint. Two randomised controlled trials have shown improved clinical outcomes and lower complication rate following arthroplasty when compared to internal fixation. Conclusion: We have presented details regarding the treatment of various types of radial head fractures - further evidence, however, is still required to provide clarity over the role of these different management strategies. PMID:29290880

  13. Fine-grained linings of leveed channels facilitate runout of granular flows

    Science.gov (United States)

    Kokelaar, B.P.; Graham, R. L.; Gray, J.M.N.T.; Vallance, James W.

    2014-01-01

    Catastrophic dense granular flows, such as occur in rock avalanches, debris flows and pyroclastic flows, move as fully shearing mixtures that have approximately 60 vol.% solids and tend to segregate to form coarse-grained fronts and leveed channels. Levees restrict spreading of unconfined flows and form as coarse particles that become concentrated in the top of the flow are transported to the front and then advect to the sides in the flow head. Channels from which most material has drained away down slope are commonly lined with fine-grained deposit, widely thought to remain from the tail of the waning flow. We show how segregation in experimental dense flows of carborundum or sand (300–425 μm) mixed with spherical fine ballotini (150–250 μm), on rough slopes of 27–29°, produces fine-grained channel linings that are deposited with the levees, into which they grade laterally. Maximum runout distance is attained with mixtures containing 30–40% sand, just sufficient to segregate and form levees that are adequately robust to restrict the spreading attributable to the low-friction fines. Resin impregnation and serial sectioning of deliberately arrested experimental flows shows how fines-lined levees form from the flow head; the flows create their own stable ‘conduit’ entirely from the front, which in a geophysical context can play an important mechanistic role in facilitating runout. The flow self-organization ensures that low-friction fines at the base of the segregated channel flow shear over fine-grained substrate in the channel, thus reducing frictional energy losses. We propose that in pyroclastic flows and debris flows, which have considerable mobility attributable to pore-fluid pressures, such fine-grained flow-contact zones form similarly and not only reduce frictional energy losses but also reduce flow–substrate permeability so as to enhance pore-fluid pressure retention. Thus the granular flow self-organization that produces fine

  14. Delayed pressure urticaria - dapsone heading for first-line therapy?

    Science.gov (United States)

    Grundmann, Sonja Alexandra; Kiefer, Sabine; Luger, Thomas Anton; Brehler, Randolf

    2011-11-01

    Pressure urticaria as a subform of physical urticaria is rare and treatment is often difficult. Established therapeutic regimes include antihistamines (generally exceeding approved dosages in order to achieve a therapeutic benefit) or antihistamines combined with montelukast. Complete relief of symptoms is difficult. We used dapsone as an early therapeutic alternative in the event of treatment failure and established a standardized therapeutic regime at our clinic. We surveyed 31 patients retrospectively who had received dapsone between 2003-2009. In 74 % of patients in whom symptoms persisted despite established therapies, the results of treatment with dapsone were good or very good. Longer-term pressure urticaria and the co-existence of a chronic spontaneous urticaria were associated with a smaller benefit (pdapsone in patients with pressure urticaria has such a good risk-benefit ratio that we support early treatment initiation. © The Authors • Journal compilation © Blackwell Verlag GmbH, Berlin.

  15. Pesticide transport to tile-drained fields in SWAT model – macropore flow and sediment

    DEFF Research Database (Denmark)

    Lu, Shenglan; Trolle, Dennis; Blicher-Mathiesen, Gitte

    2015-01-01

    as a fraction of effective rainfall and transported to the tile drains directly. Macropore sediment transport is calculated similarly to the MACRO model (Jarvis et al., 1999). Mobile pesticide transport is calculated with a decay function with the flow, whereas sorbed pesticides transport is associated......Preferential flow and colloidal facilitated transport via macopores connected to tile drains are the main pathways for pesticide transport from agricultural areas to surface waters in some area. We developed a macropore flow module and a sediment transport module for the Soil and Water Assessment...... Tool (SWAT) to simulate transport of both mobile (e.g. Bentazon) and strongly sorbed (e.g. Diuron) pesticides in tile drains. Macropore flow is initiated when soil water content exceeds a threshold and rainfall intensity exceeds infiltration capacity. The amount of macropore flow is calculated...

  16. Modeling the drain current and its equation parameters for lightly doped symmetrical double-gate MOSFETs

    Science.gov (United States)

    Bhartia, Mini; Chatterjee, Arun Kumar

    2015-04-01

    A 2D model for the potential distribution in silicon film is derived for a symmetrical double gate MOSFET in weak inversion. This 2D potential distribution model is used to analytically derive an expression for the subthreshold slope and threshold voltage. A drain current model for lightly doped symmetrical DG MOSFETs is then presented by considering weak and strong inversion regions including short channel effects, series source to drain resistance and channel length modulation parameters. These derived models are compared with the simulation results of the SILVACO (Atlas) tool for different channel lengths and silicon film thicknesses. Lastly, the effect of the fixed oxide charge on the drain current model has been studied through simulation. It is observed that the obtained analytical models of symmetrical double gate MOSFETs are in good agreement with the simulated results for a channel length to silicon film thickness ratio greater than or equal to 2.

  17. Interpretation of Cone Penetration Testing in Silty Soils Conducted under Partially Drained Conditions

    DEFF Research Database (Denmark)

    Holmsgaard, Rikke; Nielsen, Benjaminn Nordahl; Ibsen, Lars Bo

    2016-01-01

    The standard penetration rate used in cone penetration tests (CPTs) is 20 mm=s, regardless of soil type, which yields fully drained penetration in sand and fully undrained penetration in clay. However, for silty soils that represent an intermediate grain size composition and unique characteristics...... compared with sand and clay, the standard rate of penetration results in partially drained penetration, often leading to misinterpretation of this soil type. In this study, 15 CPTs, with penetration rates varying from 0.5 to 60 mm=s, were performed at a test site in northern Denmark, where the subsoil...... penetration rate. Also evaluated and presented in this paper is how cone resistance obtained under partially drained conditions underestimates the interpreted relative density Dr and friction angle ?. Triaxial test results on undisturbed silt samples were applied for this analysis. © 2015. American Society...

  18. Short-channel drain current model for asymmetric heavily / lightly doped DG MOSFETs

    Science.gov (United States)

    Dutta, Pradipta; Syamal, Binit; Koley, Kalyan; Dutta, Arka; Sarkar, C. K.

    2017-08-01

    The paper presents a drain current model for double gate metal oxide semiconductor field effect transistors (DG MOSFETs) based on a new velocity saturation model that accounts for short-channel velocity saturation effect independently in the front and the back gate controlled channels under asymmetric front and back gate bias and oxide thickness. To determine the front and the back-channel velocity saturation, drain-induced barrier lowering is evaluated by effective gate voltages at the front and back gates obtained from surface potential at the threshold condition after considering symmetric and asymmetric front and back oxide thickness. The model also incorporates surface roughness scattering and ionized impurity scattering to estimate drain current for heavily / lightly doped channel for short-channel asymmetric DG MOSFET and a good agreement has been achieved with TCAD simulations, with a relative error of around 3-7%.

  19. Use of closed suction devices and other drains in spinal surgery: results of an online, Germany-wide questionnaire.

    Science.gov (United States)

    von Eckardstein, Kajetan L; Dohmes, Jaqueline E; Rohde, Veit

    2016-03-01

    The risks of drains in spine surgery (e.g., increasing venous plexus bleeding, maintaining CSF leakage, and infections) must be balanced with their benefits (e.g., reduced rate of postoperative hematoma and seroma formation). Little is known about factors that influence surgeons' decision to employ a drain. We conducted a survey among German spine surgeons regarding their use of drains. Neurosurgical and orthopedic departments along with privately practicing neurosurgeons were invited to complete an online questionnaire featuring general and case-specific questions with regard to drain placement. We received 163 questionnaires (private practice and small-volume centers 36.1%, medium- and large-volume centers 43.6%, university centers 20.2%). Factors influencing the decision to use a drain include size of wound, type of procedure, hemostasis at the end of the procedure, and coagulopathies; factors found to be less important include overall blood loss, body mass index, and implants. 31% of surgeons will use drains for microdiskectomies. For other pathologies, percentages are as follows: anterior cervical diskectomy and fusion, 58%; cervical laminoplasty, 62%; hemilaminectomy for bisegmental lumbar stenosis, 69%; transpedicular instrumentation, 88%; vertebral body replacement for metastasis, 94%. Over half of those who usually employ a drain will not use a drain in cases of unintentional durotomy. In terms of indication, duration, and safety measures, use of drains in spinal surgery is heterogeneous. The majority of surgeons prefer drains to suction in most cases, except for microdiskectomies, for which only 31% will use a drain. Nearly all colleagues discontinue drains by day 4.

  20. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... News Physician Resources Professions Site Index A-Z Magnetic Resonance Imaging (MRI) - Head Magnetic resonance imaging (MRI) of the head uses a powerful magnetic field, radio waves and a computer to produce ...

  1. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... content. Related Articles and Media MR Angiography (MRA) Magnetic Resonance, Functional (fMRI) - Brain Head and Neck Cancer Treatment Brain Tumor Treatment Magnetic Resonance Imaging (MRI) Safety Alzheimer's Disease Head Injury Brain ...

  2. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... Articles and Media MR Angiography (MRA) Magnetic Resonance, Functional (fMRI) - Brain Head and Neck Cancer Treatment Brain Tumor Treatment Magnetic Resonance Imaging (MRI) Safety Alzheimer's Disease Head Injury Brain Tumors Images related to ...

  3. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... are the limitations of MRI of the Head? What is MRI of the Head? Magnetic resonance imaging ( ... brain) in routine clinical practice. top of page What are some common uses of the procedure? MR ...

  4. Childhood Head and Neck Irradiation

    Science.gov (United States)

    ... Thyroid Association ® www.thyroid.org Childhood Head & Neck Irradiation What is the thyroid gland? The thyroid gland ... Thyroid Association ® www.thyroid.org Childhood Head & Neck Irradiation Thyroid nodules (see Thyroid Nodule brochure) • Thyroid nodules ...

  5. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... for Brain Tumors Radiation Therapy for Head and Neck Cancer Others : American Stroke Association National Stroke Association ... MRA) Magnetic Resonance, Functional (fMRI) - Brain Head and Neck Cancer Treatment Brain Tumor Treatment Magnetic Resonance Imaging ( ...

  6. The hydrology of a drained topographical depression within an agricutlural field in north-central Iowa

    Science.gov (United States)

    Roth, Jason L.; Capel, Paul D.

    2012-01-01

    North-central Iowa is an agriculturally intensive area comprising the southeastern portion of the Prairie Pothole Region, a landscape containing a high density of enclosed topographical depressions. Artificial drainage practices have been implemented throughout the area to facilitate agricultural production. Vertical surface drains are utilized to drain the topographical depressions that accumulate water. This study focuses on the hydrology of a drained topographical depression located in a 39.5 ha agricultural field. To assess the hydrology of the drained depression, a water balance was constructed for 11 ponding events during the 2008 growing season. Continuous pond and groundwater level data were obtained with pressure transducers. Flows into the vertical surface drain were calculated based on pond depth. Precipitation inflows and evaporative outflows of the ponds were calculated using climatic data. Groundwater levels were used to assess groundwater/pond interactions. Results of the water balances show distinct differences between the inflows to and outflows from the depression based on antecedent conditions. In wet conditions, groundwater inflow sustained the ponds. The ponds receded only after the groundwater level declined to below the land surface. In drier conditions, groundwater was not a source of water to the depression. During these drier conditions, infiltration comprised 30% of the outflows from the depression during declining pond stages. Over the entire study period, the surface drain, delivering water to the stream, was the largest outflow from the pond, accounting for 97% of the outflow, while evapotranspiration was just 2%. Precipitation onto the pond surface proved to be a minor component, accounting for 4% of the total inflows.

  7. Effects of Drains on Pain, Comfort and Anxiety in Patients Undergone Surgery

    Directory of Open Access Journals (Sweden)

    Ummu Yildiz Findik

    2013-01-01

    Full Text Available Backround: Surgical drains negatively affect patients’ comfort, cause anxiety along with pain, as they are used to promote healing after surgery.Purpose: This study aimed to determine pain, comfort and anxiety levels of patients with drains postoperatively.Methodology: Research was performed with 192 patients undergone abdominal, neck, breast and open heart surgery and had surgical and underwater chest drains at the postoperative period. Patient Information Form, Numerical Pain Scale, General Comfort Questionnaire and Trait Anxiety Scale was used for collection of data. In evaluating the data, we used the t-test, variance and correlation analysis, mean, percentage and frequency.Results: The patients’ mean score of pain was 4.67±2.93, comfort was 2.75±0.29 and anxiety was 39.31±9.21. It was found statistically significant that the comfort level decreases as the pain level increases and that the patients undergone open heart surgery and with underwater chest drains have higher pain levels. It was found statistically significant that, comfort level in patients undergone abdominal or cardiac surgery is lower than patients undergone breast or neck surgery, and that the comfort level decreases as the duration of drains increases. The increasing state anxiety while pain increases and comfort decreases was found statistically significant.Conclusions: Surgeries and drains applied after these procedures decrease the comfort level of the patients as increases the pain level. Also, pain and discomfort increase the patients’ anxiety. Nurses who providing care to these patients are suggested to improve measures about pain and anxiety reduction for maintaining of comfort.

  8. Numerical simulation of draining and drying procedure for the ITER Generic Equatorial Port Plug cooling system

    Energy Technology Data Exchange (ETDEWEB)

    Tanchuk, Victor, E-mail: Victor.Tanchuk@sintez.niiefa.spb.su [JSC “D.V. Efremov Institute of Electrophysical Apparatus”, 196641 St. Petersburg (Russian Federation); Grigoriev, Sergey; Lyublin, Boris [JSC “D.V. Efremov Institute of Electrophysical Apparatus”, 196641 St. Petersburg (Russian Federation); Maquet, Philippe [ITER Organization, Route de Vinon sur Verdon, 13115 St Paul-lez-Durance (France); Senik, Konstantin [JSC “D.V. Efremov Institute of Electrophysical Apparatus”, 196641 St. Petersburg (Russian Federation); Pak, Sunil [National Fusion Research Institute, Daejeon (Korea, Republic of); Udintsev, Victor [ITER Organization, Route de Vinon sur Verdon, 13115 St Paul-lez-Durance (France)

    2016-11-01

    Highlights: • The cooling system of the ITER Generic Equatorial Port Plug (GEPP) is of a complicated combination of horizontal and vertical channels. • The calculation model for the entire GEPP cooling circuit comprising 12 sub-circuits and built up of 2421 finite-volume elements has been developed. • Transient analysis of this model simulating the draining procedure by the KORSAR/B1 code has been performed. • Water in amount of 263 g of initial 531 kg in the GEPP remains in the dead-ends of the DSM and DFW channels in 150 s of draining procedure. • Almost 3 h are required to boil off 263 g of water trapped in the dead-ends. - Abstract: For effective vacuum leak testing all cooling circuits serving the ITER vessel and in-vessel components shall be drained and dried so that after this procedure taking less than 100 h the purge gas passing through a component has water content less than 100 ppm. This process is four-stage, with the first stage using a short blast of compressed nitrogen to blow most of water in the coolant channels out of the circuit. This process is hindered by volumes which trap water due to gravity. To remove the trapped water, it is necessary, first, to heat up the structure by hot and compressed nitrogen, and then water is evaporated by depressurized nitrogen. The cooling system of the ITER Diagnostic Equatorial Port Plugs is of a complicated hydraulic configuration. The system branching might make difficult removal of water from the piping in the scheduled draining mode. The authors have proposed the KORSAR computation code to simulate draining of the GEPP cooling circuit. The numerical simulation performed has made it possible to describe the process dynamics during draining of the entire GEPP cooling circuit and to define the process time, amount and location of residual water and evolution of two-phase flow regime.

  9. Symptoms from repeated intentional and unintentional head impact in soccer players.

    Science.gov (United States)

    Stewart, Walter F; Kim, Namhee; Ifrah, Chloe S; Lipton, Richard B; Bachrach, Tamar A; Zimmerman, Molly E; Kim, Mimi; Lipton, Michael L

    2017-02-28

    To determine the rate and differential contribution of heading vs unintentional head impacts (e.g., head to head, goal post) to CNS symptoms in adult amateur soccer players. Amateur soccer players completed baseline and serial on-line 2-week recall questionnaires (HeadCount) and reported (1) soccer practice and games, (2) heading and unintentional soccer head trauma, and (3) frequency and severity (mild to very severe) of CNS symptoms. For analysis, CNS symptoms were affirmed if one or more moderate, severe, or very severe episodes were reported in a 2-week period. Repeated measures logistic regression was used to assess if 2-week heading exposure (i.e., 4 quartiles) or unintentional head impacts (i.e., 0, 1, 2+) were associated with CNS symptoms. A total of 222 soccer players (79% male) completed 470 HeadCount questionnaires. Mean (median) heading/2 weeks was 44 (18) for men and 27 (9.5) for women. One or more unintentional head impacts were reported by 37% of men and 43% of women. Heading-related symptoms were reported in 20% (93 out of 470) of the HeadCounts. Heading in the highest quartile was significantly associated with CNS symptoms (odds ratio [OR] 3.17, 95% confidence interval [CI] 1.57-6.37) when controlling for unintentional exposure. Those with 2+ unintentional exposures were at increased risk for CNS symptoms (OR 6.09, 95% CI 3.33-11.17) as were those with a single exposure (OR 2.98, 95% CI 1.69-5.26) when controlling for heading. Intentional (i.e., heading) and unintentional head impacts are each independently associated with moderate to very severe CNS symptoms. © 2017 American Academy of Neurology.

  10. Looped Penrose Drain for Minimally Invasive Treatment of Complex Superficial Abscesses of the Hand

    Science.gov (United States)

    Ugrinich, Marija; Chang, Benjamin

    2009-01-01

    Complex superficial abscesses are a common occurrence that traditionally have been treated by making relatively large incisions over the surface of the abscess, in order to ensure drainage and access for packing and dressing changes. The authors outline a minimally invasive technique that can be used for draining complex subcutaneous abscesses that extend over a large surface area. It is a simple technique utilizing multiple small incisions and looped penrose drains. This technique has been found to be very effective in many areas of the body and has multiple advantages over traditional incision, drainage, gauze packing, and dressing changes. PMID:19921343

  11. An Automated Approach to Agricultural Tile Drain Detection and Extraction Utilizing High Resolution Aerial Imagery and Object-Based Image Analysis

    Science.gov (United States)

    Johansen, Richard A.

    Subsurface drainage from agricultural fields in the Maumee River watershed is suspected to adversely impact the water quality and contribute to the formation of harmful algal blooms (HABs) in Lake Erie. In early August of 2014, a HAB developed in the western Lake Erie Basin that resulted in over 400,000 people being unable to drink their tap water due to the presence of a toxin from the bloom. HAB development in Lake Erie is aided by excess nutrients from agricultural fields, which are transported through subsurface tile and enter the watershed. Compounding the issue within the Maumee watershed, the trend within the watershed has been to increase the installation of tile drains in both total extent and density. Due to the immense area of drained fields, there is a need to establish an accurate and effective technique to monitor subsurface farmland tile installations and their associated impacts. This thesis aimed at developing an automated method in order to identify subsurface tile locations from high resolution aerial imagery by applying an object-based image analysis (OBIA) approach utilizing eCognition. This process was accomplished through a set of algorithms and image filters, which segment and classify image objects by their spectral and geometric characteristics. The algorithms utilized were based on the relative location of image objects and pixels, in order to maximize the robustness and transferability of the final rule-set. These algorithms were coupled with convolution and histogram image filters to generate results for a 10km2 study area located within Clay Township in Ottawa County, Ohio. The eCognition results were compared to previously collected tile locations from an associated project that applied heads-up digitizing of aerial photography to map field tile. The heads-up digitized locations were used as a baseline for the accuracy assessment. The accuracy assessment generated a range of agreement values from 67.20% - 71.20%, and an average

  12. High Line

    DEFF Research Database (Denmark)

    Kiib, Hans

    2015-01-01

    factories and warehouses on Gansevoort Street. Today the High Line is a beautiful park covered with new tiles, viewing platforms and smaller recreational areas. The park bridge has simple, uniform, urban fittings and features a variety of flowering plants, grasses, shrubs and trees from around the world......, and galleries. With the High Line, a new urban architectural typology has been created that is aesthetically enriching and sets new standards for urban transformation and urban life. “The park accommodates the wild, the cultivated, the intimate and the social. Access points are durational experiences designed...

  13. Where are we heading

    Energy Technology Data Exchange (ETDEWEB)

    Noto, L.A. [Mobil Corporation, (United States)

    1996-12-31

    The present paper deals with different aspects connected to the global petroleum industry by discussing the way of heading. The aspects cover themes like new frontiers, new relationships, sanctions, global climate change, new alliances and new technology. New frontiers and relationships concern domestic policy affecting the industry, and sanctions are discussed in connection with trade. The author discusses the industry`s participation in the global environmental policy and new alliances to provide greater opportunity for developing new technology

  14. Radial Head Fractures

    OpenAIRE

    Jordan, Robert W.; Jones, Alistair DR.

    2017-01-01

    Background: Radial head fractures are common elbow injuries in adults and are frequently associated with additional soft tissue and bone injuries. Methods: A literature search was performed and the authors’ personal experiences are reported. Results: Mason type I fractures are treated non-operatively with splinting and early mobilisation. The management of Mason type II injuries is less clear with evidence supporting both non-operative treatment and internal fixation. The degree of intra-arti...

  15. Venous injury in abusive head trauma

    Energy Technology Data Exchange (ETDEWEB)

    Choudhary, Arabinda K. [Nemours A. I. duPont Hospital for Children, Department of Radiology, Wilmington, DE (United States); Bradford, Ray; Thamburaj, K.; Boal, Danielle K.B. [Hershey Medical Center, Department of Radiology, Hershey, PA (United States); Dias, Mark S. [Hershey Medical Center, Department of Neurosurgery, Hershey, PA (United States)

    2015-11-15

    Abusive head trauma (AHT) is an important cause of serious brain injury in infants and young children who have characteristic clinical and imaging findings that are discordant with the clinical history provided. Recent attention has focused on abnormalities of the cranial venous sinuses and cortical veins, both on MRI and at autopsy. Although many have interpreted these to be secondary to the AHT, some have recently argued that these venous abnormalities represent primary cortical sinus and venous thrombosis that leads secondarily to subdural hemorrhage and secondary brain injury. Direct trauma to the veins and sinuses has been reported at autopsy in AHT, but there has been no systematic study of venous abnormalities in cases of AHT. The purpose of this study was to define the incidence and characteristics of venous and sinus abnormalities in AHT. We included all children <36 months of age who were diagnosed with abusive head trauma between 2001 and 2012 and who had MRI and magnetic resonance (MR) venography as part of their diagnostic workup. We analyzed age, gender and clinical findings. MRI and MR venography were analyzed independently by two neuroradiologists with a focus on abnormalities involving the intracranial veins and venous sinuses. A total of 45 children were included. The median age was 3 months (range 15 days to 31 months) and 28 were boys (62%). Clinical findings included retinal hemorrhage in 71% and extracranial fractures in 55%. CT or MRI demonstrated subdural hemorrhage in 41 (91%); none had subdural effusions. In 31 cases (69%) MR venography demonstrated mass effect on the venous sinuses or cortical draining veins, with either displacement or partial or complete effacement of the venous structures from an adjacent subdural hematoma or brain swelling. We also describe the lollipop sign, which represents direct trauma to the cortical bridging veins and was present in 20/45 (44%) children. Evidence of displacement or compression of cortical veins

  16. DETERMINATION OF LIQUID FILM THICKNESS FOLLOWING DRAINING OF CONTACTORS, VESSELS, AND PIPES IN THE MCU PROCESS

    Energy Technology Data Exchange (ETDEWEB)

    Poirier, M; Fernando Fondeur, F; Samuel Fink, S

    2006-06-06

    The Department of Energy (DOE) identified the caustic side solvent extraction (CSSX) process as the preferred technology to remove cesium from radioactive waste solutions at the Savannah River Site (SRS). As a result, Washington Savannah River Company (WSRC) began designing and building a Modular CSSX Unit (MCU) in the SRS tank farm to process liquid waste for an interim period until the Salt Waste Processing Facility (SWPF) begins operations. Both the solvent and the strip effluent streams could contain high concentrations of cesium which must be removed from the contactors, process tanks, and piping prior to performing contactor maintenance. When these vessels are drained, thin films or drops will remain on the equipment walls. Following draining, the vessels will be flushed with water and drained to remove the flush water. The draining reduces the cesium concentration in the vessels by reducing the volume of cesium-containing material. The flushing, and subsequent draining, reduces the cesium in the vessels by diluting the cesium that remains in the film or drops on the vessel walls. MCU personnel requested that Savannah River National Laboratory (SRNL) researchers conduct a literature search to identify models to calculate the thickness of the liquid films remaining in the contactors, process tanks, and piping following draining of salt solution, solvent, and strip solution. The conclusions from this work are: (1) The predicted film thickness of the strip effluent is 0.010 mm on vertical walls, 0.57 mm on horizontal walls and 0.081 mm in horizontal pipes. (2) The predicted film thickness of the salt solution is 0.015 mm on vertical walls, 0.74 mm on horizontal walls, and 0.106 mm in horizontal pipes. (3) The predicted film thickness of the solvent is 0.022 mm on vertical walls, 0.91 mm on horizontal walls, and 0.13 mm in horizontal pipes. (4) The calculated film volume following draining is: (a) Salt solution receipt tank--1.6 gallons; (b) Salt solution feed

  17. The lymphatic vascular system of the mouse head.

    Science.gov (United States)

    Lohrberg, Melanie; Wilting, Jörg

    2016-12-01

    Histological studies of the lymphatic vascular system in adult mice are hampered because bones cannot be sectioned properly. Here, we decalcified the heads of 14-day-old mice, embedded them in paraffin and stained resultant serial sections with the lymphendothelial-specific antibodies Lyve-1 and Podoplanin. We show that the tissues with the highest lymphatic vascular density are the dermis and the oral mucous membranes. In contrast, the nasal mucous membrane is devoid of lymphatics, except for its most basal parts below the vomeronasal organ. The inferior nasal turbinate contains numerous lymphatics and is connected to the nasolacrimal duct (NLD), which is ensheathed by a dense network of lymphatics. The lymphatics of the eye lids and conjunctiva are connected to those of the inferior nasal turbinate. We suggest that cerebro-spinal fluid (CSF) can drain via the optic nerve and NLD lymphatics, whereas CSF drained via the Fila olfactoria into the nasal mucous membrane is used for moisturization of the respiratory air. Tongue, palatine and buccal mucous membranes possess numerous lymphatics, whereas the dental pulp has none. Lymphatics are present in the maxillary gland and close to the temporomandibular joint, suggesting the augmentation of lymph flow by chewing and yawning. Lymphatics can also be found in the dura mater and in the dural septae entering into deeper parts of the brain. Our findings are discussed with regard to CSF drainage and potential routes for ocular tumor dissemination.

  18. Lipoabdominoplasty without drains or progressive tension sutures: an analysis of 100 consecutive patients.

    Science.gov (United States)

    Epstein, Sarah; Epstein, Michael A; Gutowski, Karol A

    2015-05-01

    Subcutaneous surgical drains are commonly used in abdominoplasties to prevent seromas but are not tolerated well by patients and add additional discomfort after the procedure. The lipoabdominoplasty modification may create a more favorable surgical field to reduce the need for surgical drains without increasing seroma formation. The goal of this review was to determine if surgical drains can be completely eliminated in lipoabdominoplasty procedures without an increased risk of seromas. The authors conducted a retrospective chart review of 100 consecutive standard, extended, and circumferential lipoabdominoplasty patients done by a single surgeon with at least a 3-month follow-up period. Seroma was identified in 5% of patients, hematoma and abscess each in 2% of patients, and granuloma, cellulitis, and delayed wound healing each in 1% of patients. The use of discontinuous undermining with liposuction, limited direct undermining in the midline, preservation of a thin layer of fibrofatty tissue on the superficial abdominal wall fascia, and targeted surgical site compression can eliminate the need for surgical drains without increasing seroma rates. © 2015 The American Society for Aesthetic Plastic Surgery, Inc. Reprints and permission: journals.permissions@oup.com.

  19. X-DRAIN and XDS: a simplified road erosion prediction method

    Science.gov (United States)

    William J. Elliot; David E. Hall; S. R. Graves

    1998-01-01

    To develop a simple road sediment delivery tool, the WEPP program modeled sedimentation from forest roads for more than 50,000 combinations of distance between cross drains, road gradient, soil texture, distance from stream, steepness of the buffer between the road and the stream, and climate. The sediment yield prediction from each of these runs was stored in a data...

  20. Increased water yields following harvesting operations on a drained coastal watershed

    Science.gov (United States)

    Johnny M. Grace; R.W. Skaggs; H.R. Malcom; G.M. Chescheir; D.K. Cassel

    2003-01-01

    Forest harvesting operations have been reported to affect annual and seasonal outflow characteristics from drained forest watersheds. Increases in forest outflow, nutrient concentrations, and suspended sediments are commonly seen as a result of these forest management activities. Thus, it is important to assess the impact of forest management activities on hydrology,...

  1. Observation Bias Correction Reveals More Rapidly Draining Lakes on the Greenland Ice Sheet

    Science.gov (United States)

    Cooley, Sarah W.; Christoffersen, Poul

    2017-10-01

    Rapid drainage of supraglacial lakes on the Greenland Ice Sheet enables the establishment of surface-to-bed hydrologic connections and subsequent basal water delivery. Estimates of the number and spatial distribution of rapidly draining lakes vary widely, and no study has so far quantified the impact of observation bias due to cloud cover in satellite imagery on reported frequency of rapid lake drainage. To better understand the rapid drainage mechanism, we map and track an average of 515 supraglacial lakes per year in central West Greenland from 2000 to 2015. We test four previously published definitions of rapid lake drainage and find the proportion of rapidly draining lakes to vary from 3% to 38% and to be strongly dependent on observation frequency. We then apply an observation bias correction and test three new drainage criteria, which reveal a bias-corrected rapid drainage probability of 36-45%. When observation bias is addressed, we can also show that lakes above 1,600 m are as likely to drain rapidly as lakes located at lower elevations. We conclude that inconsistent detection methodologies and observation bias have obscured the true frequency of rapidly draining lakes and that the rapid lake drainage mechanism will establish surface-to-bed hydrologic connections at increasing distance from the margin as supraglacial lakes expand inland under climate warming.

  2. Human capital in European peripheral regions: brain - drain and brain - gain

    NARCIS (Netherlands)

    Coenen, Franciscus H.J.M.

    2004-01-01

    Project goal - The overall goal of the project is to build a legitimate transnational network to transfer ideas and experiences and implement measures to reduce brain drain and foster brain gain while reinforcing the economical and spatial development of peripheral regions in NWE. This means a

  3. Antimony retention and release from drained and waterlogged shooting range soil under field conditions

    NARCIS (Netherlands)

    Hockmann, K.; Tandy, S.; Lenz, M.; Reiser, R.; Conesa, H.; Keller, M.; Studer, B.; Schulin, R.

    2015-01-01

    Many soils polluted by antimony (Sb) are subject to fluctuating waterlogging conditions; yet, little is known about how these affect the mobility of this toxic element under field conditions. Here, we compared Sb leaching from a calcareous shooting range soil under drained and waterlogged conditions

  4. Photoactive TiO2 Films Formation by Drain Coating for Endosulfan Degradation

    Directory of Open Access Journals (Sweden)

    Natalia Tapia-Orozco

    2013-01-01

    Full Text Available Heterogeneous photocatalysis is an advanced oxidation process in which a photoactive catalyst, such as TiO2, is attached to a support to produce free radical species known as reactive oxygen species (ROS that can be used to break down toxic organic compounds. In this study, the draining time, annealing temperature, and draining/annealing cycles for TiO2 films grown by the drain coating method were evaluated using a 23 factorial experimental design to determine the photoactivity of the films via endosulfan degradation. The TiO2 films prepared with a large number of draining/annealing cycles at high temperatures enhanced (P>0.05 endosulfan degradation and superoxide radical generation after 30 minutes of illumination with UV light. We demonstrated a negative correlation (R2=0.69; P>0.01 between endosulfan degradation and superoxide radical generation. The endosulfan degradation rates were the highest at 30 minutes with the F6 film. In addition, films prepared using conditions F1, F4, and F8 underwent an adsorption/desorption process. The kinetic reaction constants, Kapp (min−1, were 0.0101, 0.0080, 0.0055, 0.0048, and 0.0035 for F6, F2, F5, F3, and F1, respectively. The endosulfan metabolites alcohol, ether, and lactone were detected and quantified at varying levels in all photocatalytic assays.

  5. Oral tolerance is determined at the level of draining lymph nodes

    NARCIS (Netherlands)

    Wilsem, van E.G.; BrevÃ, J.; Savelkoul, H.; Claessen, A.; Scheper, R.J.; Kraal, G.

    1995-01-01

    In the skin and in the epithelium of the oral mucosa a comparable network of Langerhans cells can be found. Antigen application on either epithelium leads to rapid emigration of Langerhans cells to the draining lymph nodes. Application on the oral mucosa leads to tolerance induction while

  6. Outcome in primary cemented total knee arthroplasty with or without drain A prospective comparative study

    Directory of Open Access Journals (Sweden)

    Rafal Keska

    2014-01-01

    Conclusions: The present study conclude that there is no rationale for the use of drain after primary TKA. There are benefits in terms of lower opioid intake, lower blood loss on the first postoperative day and lower need for dressing reinforcement during hospitalization.

  7. Assessing the role of artificially drained agricultural land for climate change mitigation in Ireland

    NARCIS (Netherlands)

    Paul, Carsten; Fealy, Réamonn; Fenton, Owen; Lanigan, Gary; O'Sullivan, Lilian; Schulte, Rogier P.O.

    2018-01-01

    In 2014 temperate zone emission factor revisions were published in the IPCC Wetlands Supplement. Default values for direct CO2 emissions of artificially drained organic soils were increased by a factor of 1.6 for cropland sites and by factors ranging from 14 to 24 for grassland sites. This

  8. Development and testing of watershed-scale models for poorly drained soils

    Science.gov (United States)

    Glenn P. Fernandez; George M. Chescheir; R. Wayne Skaggs; Devendra M. Amatya

    2005-01-01

    Watershed-scale hydrology and water quality models were used to evaluate the crrmulative impacts of land use and management practices on dowrzstream hydrology and nitrogen loading of poorly drained watersheds. Field-scale hydrology and nutrient dyyrutmics are predicted by DRAINMOD in both models. In the first model (DRAINMOD-DUFLOW), field-scale predictions are coupled...

  9. Nutrient limitations in wet, drained and rewetted fen meadows : evaluation of methods and results

    NARCIS (Netherlands)

    Van Duren, IC; Pegtel, DM

    2000-01-01

    Restoration of wet grassland communities on peat soils involves management of nutrient supply and hydrology. The concept of nutrient limitation was discussed as well as its interaction with drainage and rewetting of severely drained peat soils. Different methods of assessing nutrient limitation were

  10. Brain drain as a clog in the wheel of Nigeria's development: The ...

    African Journals Online (AJOL)

    This study critically examines the brain drain phenomenon and its causes in Nigeria. These causes range from lack of employment, poor remuneration for top flight intellectuals and professionals, political instability, security risks to lack of research and other facilities (including inadequacy of research funds and professional ...

  11. External ventricular drain as a nontraumatic suction device in carotid endarterectomy

    OpenAIRE

    Jukes, Alistair; Allan, Rodney

    2017-01-01

    Carotid endarterectomy is a commonly performed operation to remove plaque at the region of the carotid bifurcation. We present our technique to keep the field clear and to minimize potential trauma to the carotid using a neurosurgical external ventricular drain passed behind the common carotid and placed in the dependent position under the arteriotomy.

  12. External ventricular drain as a nontraumatic suction device in carotid endarterectomy

    Directory of Open Access Journals (Sweden)

    Alistair Jukes, MBBS(Hons, BLibStud

    2017-03-01

    Full Text Available Carotid endarterectomy is a commonly performed operation to remove plaque at the region of the carotid bifurcation. We present our technique to keep the field clear and to minimize potential trauma to the carotid using a neurosurgical external ventricular drain passed behind the common carotid and placed in the dependent position under the arteriotomy.

  13. Academic Brain Drain: Impact and Implications for Public Higher Education Quality in Kenya

    Science.gov (United States)

    Odhiambo, George O.

    2013-01-01

    The flight of human capital is a phenomenon that has been of concern to academics and development practitioners for decades. Unfortunately, there is no systematic record of the number of skilled professionals that many African countries have continued to lose to the developed world. Termed the "brain drain", it represents the loss of…

  14. The Brain Drain in Mexico--A Subject for Research...or Agenda?

    Science.gov (United States)

    Aupetit, Sylvie Didou

    2006-01-01

    The purpose of this article is to analyse the present state of the discussion and data regarding the brain drain in Mexico. From current data, recent trends show certain peculiarities in the national picture, pointing to an increase in the number of free movers, and a decrease in the number of young people who obtain Mexican government…

  15. Restructuring brain drain: strengthening governance and financing for health worker migration.

    Science.gov (United States)

    Mackey, Tim K; Liang, Bryan A

    2013-01-15

    Health worker migration from resource-poor countries to developed countries, also known as ''brain drain'', represents a serious global health crisis and a significant barrier to achieving global health equity. Resource-poor countries are unable to recruit and retain health workers for domestic health systems, resulting in inadequate health infrastructure and millions of dollars in healthcare investment losses. Using acceptable methods of policy analysis, we first assess current strategies aimed at alleviating brain drain and then propose our own global health policy based solution to address current policy limitations. Although governments and private organizations have tried to address this policy challenge, brain drain continues to destabilise public health systems and their populations globally. Most importantly, lack of adequate financing and binding governance solutions continue to fail to prevent health worker brain drain. In response to these challenges, the establishment of a Global Health Resource Fund in conjunction with an international framework for health worker migration could create global governance for stable funding mechanisms encourage equitable migration pathways, and provide data collection that is desperately needed.

  16. Reverse Brain Drain of South Asian IT Professionals: A Quantitative Repatriation Study

    Science.gov (United States)

    Suppiah, Nithiyananthan

    2014-01-01

    The purpose of the present quantitative correlational study was to examine if a relationship existed between the RBD phenomenon and cultural, economic, or political factors of the native countries of South Asian IT professionals living in the United States. The study on reverse brain drain was conducted to explore a growing phenomenon in the…

  17. Brain drain of brain gain? Hoger opgeleiden in grote steden in Nederland

    NARCIS (Netherlands)

    Venhorst, V.A; Edzes, A.J.E.; Broersma, L.; Dijk, J. van

    2011-01-01

    Voor u ligt de eindrapportage van het Nicis onderzoeksproject ‘Hoger opgeleiden in grote steden in Nederland; Brain drain of brain gain?’. Gemeenten in Nederland maken zich zorgen over de mate waarin ze afgestudeerden voor de eigen arbeids- en woningmarkt kunnen behouden. Er is zowel vanuit de

  18. Stopping the Brain Drain of Skilled Veteran Teachers: Retaining and Valuing Their Hard-Won Experience

    Science.gov (United States)

    Fibkins, William L.

    2011-01-01

    Veteran educators are being encouraged to take early retirement in order to create jobs for less-experienced, lower-paid novices. Veteran educators are not alone: early retirement promotions have become the norm for aging workers in America. Consequently, there is a brain-drain of skilled workers at the national, state, and local levels. The early…

  19. Impact of drain water on water quality and eutrophication status of ...

    African Journals Online (AJOL)

    The ecological and biological status of Lake Burullus was examined in 2006 to determine its water quality and eutrophication status in response to the quality and quantity of drain water entering it. The lake suffers from excessive nutrient concentrations. Chlorophyll a showed wide variations over the sampling period with ...

  20. The routine use of post-operative drains in thyroid surgery: an outdated concept.

    LENUS (Irish Health Repository)

    Prichard, R S

    2010-01-01

    The use of surgical drains in patients undergoing thyroid surgery is standard surgical teaching. Life-threatening complications, arising from post-operative haematomas, mandates their utilization. There is increasing evidence to suggest that this is an outdated practice. This paper determines whether thyroid surgery can be safely performed without the routine use of drains. A retrospective review of patients undergoing thyroid surgery, over a three year period was performed and post-operative complications documented. One hundred and four thyroidectomies were performed. 63 (60.6%) patients had a partial thyroidectomy, 27 (25.9%) had a total thyroidectomy and 14 (13.5%) had a sub-total thyroidectomy. Suction drains were not inserted in any patient. A cervical haematoma did not develop in any patient in this series and no patient required re-operation. There is no evidence to suggest the routine use of surgical drains following uncomplicated thyroid surgery reduces the rate of haematoma formation or re-operation rates and indeed is now unwarranted.

  1. Long-term hydrology and water quality of a drained pine plantation in North Carolina

    Science.gov (United States)

    D.M. Amatya; R.W. Skaggs

    2011-01-01

    Long-term data provide a basis for understanding natural variability, reducing uncertainty in model inputs and parameter estimation, and developing new hypotheses. This article evaluates 21 years (1988-2008) of hydrologic data and 17 years (1988-2005) of water quality data from a drained pine plantation in eastern North Carolina. The plantation age was 14 years at the...

  2. Addressing agricultural phosphorus loss in artificially drained landscapes with 4R nutrient management practices

    Science.gov (United States)

    Agricultural phosphorus (P) loss has been linked to the eutrophication of surface water bodies throughout the world and minimizing offsite P transport continues to be a priority in many watersheds. In the U.S. Midwest and other tile-drained regions, there is a critical need to identify nutrient mana...

  3. 76 FR 62605 - Virginia Graeme Baker Pool and Spa Safety Act; Interpretation of Unblockable Drain

    Science.gov (United States)

    2011-10-11

    ... COMMISSION 16 CFR Part 1450 Virginia Graeme Baker Pool and Spa Safety Act; Interpretation of Unblockable... ``unblockable drain'' as used in the Virginia Graeme Baker Pool and Spa Safety Act (``VGB Act'').\\1\\ \\1\\ The... pools and spas be in compliance with the VGB Act, which became effective December 19, 2008. Any public...

  4. Quality Education Improvement: Yemen and the Problem of the "Brain Drain"

    Science.gov (United States)

    Muthanna, Abdulghani

    2015-01-01

    This paper presents an overview of the problems that hinder improvement of the quality of education in Yemen, with a particular focus on higher education institutions. It discusses in particular the problem of the brain drain and why this phenomenon is occurring in Yemen. Semi-structured interviews with three professors at higher education…

  5. Drainage Water Salinity of Tubewells and Pipe Drains: A Case Study from Pakistan

    NARCIS (Netherlands)

    Kelleners, T.J.; Chaudhry, M.R.

    1998-01-01

    Drainage water salinity data from 71 public deep tubewells and 79 pipe drainage units near Faisalabad, Pakistan, were studied. Drainage water salinity of the tubewells and the pipe drains remained approximately constant with time. This was attributed to the deep, highly conductive, unconfined

  6. Corn stover harvest increases herbicide movement to subsurface drains – Root Zone Water Quality Model simulations

    Science.gov (United States)

    BACKGROUND: Removal of crop residues for bioenergy production can alter soil hydrologic properties, but there is little information on its impact on transport of herbicides and their degradation products to subsurface drains. The Root Zone Water Quality Model, previously calibrated using measured fl...

  7. 40 CFR 63.136 - Process wastewater provisions-individual drain systems.

    Science.gov (United States)

    2010-07-01

    ... carrying Group 1 wastewater are not required to have a flexible cap or extended subsurface discharging pipe..., the owner or operator shall either extend the pipe discharging the wastewater below the liquid surface in the water seal of the receiving drain, or install a flexible shield (or other enclosure which...

  8. Enterococcus faecalis surface proteins determine its adhesion mechanism to bile drain materials

    NARCIS (Netherlands)

    Waar, K; van der Mei, HC; Harmsen, HJM; Degener, JE; Busscher, HJ

    An important step in infections associated with biliary drains is adhesion of micro-organisms to the surface. In this study the role of three surface proteins of Enterococcus faecalis (enterococcal surface protein, aggregation substances 1 and 373) in the adhesion to silicone rubber,

  9. Analytical Solution for Transient Water Table Heights and Outflows from Inclined Ditch-Drained Terrains

    NARCIS (Netherlands)

    Verhoest, N.E.C.; Pauwels, V.R.N.; Troch, P.A.; Troch, De F.P.

    2002-01-01

    This paper presents two analytical solutions of the linearized Boussinesq equation for an inclined aquifer, drained by ditches, subjected to a constant recharge rate. These solutions are based on different initial conditions. First, the transient solution is obtained for an initially fully saturated

  10. Impacts of fertilization on water quality of a drained pine plantation: a worse case scenario

    Science.gov (United States)

    Bray J. Beltran; Devendra M. Amatya; Mohamed Youssef; Martin Jones; Timothy J. Skaggs Callahan

    2010-01-01

    Intensive plantation forestry will be increasingly important in the next 50 yr to meet the high demand for domestic wood in the United States. However, forest management practices can substantially infl uence downstream water quality and ecology. Th is study analyses, the eff ect of fertilization on effl uent water quality of a low gradient drained coastal pine...

  11. Performance Evaluation and Design Considerations of Electrically Activated Drain Extension Tunneling GNRFET: A Quantum Simulation Study

    Science.gov (United States)

    Ghoreishi, Seyed Saleh; Yousefi, Reza; Taghavi, Neda

    2017-11-01

    In this paper, a tunneling graphene nanoribbon field effect transistor with electrically activated drain extension, namely, EA-T-GNRFET, is proposed. The proposed structure includes a side gate at the drain side with a constant voltage and length of 0.4 V and 15 nm, respectively. Simulations are performed based on the non-equilibrium Green's function method coupled with the Poisson equation in the mode space representation. This side gate creates an additional step in potential profile at the drain side, which increases and decreases the width of tunneling barrier and leakage current, respectively. Furthermore, the proposed structure has lower drain induced barrier thinning, lower sub-threshold swing (SS) and higher I ON/ I OFF ratio than the conventional structure. Also, other characteristics of the device such as switching delay ( τ ), power delay product (PDP) and unity-gain frequency ( f t) are improved in the proposed device. These advantages make EA-T-GNRFET more suitable for digital and analog applications.

  12. Structure of a steady drain-hole vortex in a viscous fluid

    DEFF Research Database (Denmark)

    Bøhling, Lasse; Andersen, Anders Peter; Fabre, D.

    2010-01-01

    We use direct numerical simulations to study a steady bathtub vortex in a cylindrical tank with a central drain-hole, a fiat stress-free surface and velocity prescribed at the inlet. We find that the qualitative structure of the meridional flow does not depend on the radial Reynolds number, where...

  13. Phosphorus dynamics in long-term flooded, drained and reflooded soils

    Science.gov (United States)

    In flooded areas, soils are often exposed to standing water and subsequent drainage, thus over fertilization can release excess phosphorus (P) into surface water and groundwater. To investigate P release and transformation processes in flooded alkaline soils, we flooded-drained-reflooded two soils f...

  14. Computed Tomography (CT) -- Head

    Medline Plus

    Full Text Available ... exam, it will be swallowed, injected through an intravenous line (IV) or, rarely, administered by enema. Next, ... you tolerate the CT scanning procedure. If an intravenous contrast material is used, you will feel a ...

  15. Effect of One versus Two Drain Insertion on Postoperative Seroma Formation after Modified Radical Mastectomy

    Directory of Open Access Journals (Sweden)

    farzaneh ebrahimifard

    2016-04-01

    Full Text Available Background: Modified radical mastectomy (MRM is still one of globally accepted surgical techniques for breast cancer and in some selected patient is the gold standard type of surgery. The most frequent complication of this procedure is seroma under skin flaps or in the axilla as reported as much as 30% in some studies. The use of closed suction drainage system to reduce the incidence of this complication has been routinely accepted by surgeons; however, length of catheter stay and the number of catheters inserted in the wound are still controversial. The present study compares the results of single versus double drain insertion in patients undergoing MRM for breast cancer.Materials and Methods: The study was conducted on 100 women with breast cancer who were candidate for MRM surgery during 2007-2010 referred to Modarres hospital, Tehran, Iran as a randomized group matched controlled trial.Results: There was no significant difference between the two groups in terms of age, BMI, and tumor weight (P=0.406 (Table 1. Similarly, the difference between the two groups was insignificant in tumor size (T and number of lymph nodes involved (P=0.145. There was no significant difference between the two groups in timing of axillary drain removal (P=0.064. No significant differences were observed between the two groups in mean aspirated fluid (P=0.071 and mean aspirated sera (P=0.484 after removal of drains.Conclusion: This study revealed one drain insertion in MRM surgery is as effective as two drain and probably less morbidity and cost.

  16. Continuous high-pressure negative suction drain: new powerful tool for closed wound management: clinical experience.

    Science.gov (United States)

    Shin, Seung Jun; Han, DaeHee; Song, Hyunsuk; Jang, Yu Jin; Park, Dong Ha; Park, Myong Chul

    2014-07-01

    Although various reconstructive flap surgeries have been successfully performed, there still are difficult wound complications, such as seroma formation, wound margin necrosis, delayed wound healing, and even flap failures. The negative-pressure wound therapy has been described in detail in the literature to assist open chronic/complex wound closure in reconstructive surgery. However, the negative-pressure wound therapy was difficult to be applied under the incisional closed wounds. A total of 23 patients underwent the various reconstructive flap surgeries with continuous high-pressure negative suction drain. Instead of using regular suction units, Barovac (50-90 mm Hg, Sewoon Medical, Seoul, Republic of Korea) drainage tubes were connected to the wall suction unit, providing continuous high-powered negative pressure. In addition, continuous subatmospheric suction pressure (100-300 mm Hg) was applied. Outcome of the measures was obtained from the incidence of seroma, volume of postoperative drainage, hospitalization period, and incidence of other typical wound complications. Dead space was evaluated postoperatively with ultrasonography. Using continuous high-pressure negative suction drain, successful management of seroma was obtained without any major complication such as wound infection, flap loss, and wound margin necrosis, except for only 1 case of seroma after discharge from the hospital. The indwelling time of the drain in the latissimus dorsi donor site was significantly reduced in comparison with the authors' previous data (P = 0.047). The volume of drainage and hospitalization period were also reduced; however, these were not statistically significant. The dead space with continuous high-pressure negative suction drain was more reduced than in the control group in the immediate postoperative period and confirmed with ultrasonography. Continuous high-pressure negative suction drain might be the simple and powerful solution in the management of challenging

  17. Disinfection of drain water of tomato by means of UV radiation and slow sand filtration in real greenhouse circumstances.

    Science.gov (United States)

    De Rocker, E; Goen, K; Van Poucke, K

    2006-01-01

    The efficiency of the disinfection of drain water was tested at 11 greenhouses with tomato cultivation on rockwool substrate in Flanders (Belgium) by means of mycological analysis. In addition the presence of phytopathogenic fungi in the drain water was analysed at 2 supplementary greenhouses with recirculation without disinfection.

  18. Beyond Brain Drain: The Dynamics of Geographic Mobility and Educational Attainment of B.C. Young Women and Men

    Science.gov (United States)

    Andres, Lesley; Licker, Aaron

    2004-01-01

    In recent years, the topic of "brain drain" has gained considerable attention, both in public and intellectual spheres. Despite the media frenzy, few data sets and related studies exist to examine the nature and extent to which brain drain occurs. The purpose of this study is to extend the scope of the way we think about "brain…

  19. Novel pod for chlorine dioxide generation and delivery to control aerobic bacteria on the inner surface of floor drains

    Science.gov (United States)

    Floor drains in poultry processing and further processing plants are a harborage site for bacteria both free swimming and in biofilms. This population can include Listeria monocytogenes which has been shown to have potential for airborne spreading from mishandled open drains. Chlorine dioxide (ClO...

  20. Viscosity-dependent drain current noise of AlGaN/GaN high electron mobility transistor in polar liquids

    Energy Technology Data Exchange (ETDEWEB)

    Fang, J. Y.; Hsu, C. P.; Kang, Y. W.; Fang, K. C.; Kao, W. L.; Yao, D. J.; Chen, C. C.; Li, S. S.; Yeh, J. A.; Wang, Y. L. [Institute of Nanoengineering and Microsystems, National Tsing Hua University, Hsinchu 300, Taiwan (China); Lee, G. Y.; Chyi, J. I. [Department of Electrical engineering, National Central University, Jhongli City, Taoyuan County 32001, Taiwan (China); Hsu, C. H. [Division of Medical Engineering, National Health Research Institutes, MiaoLi, Taiwan (China); Huang, Y. F. [Department of Biomedical Engineering and Environmental Science, National Tsing Hua University, Hsinchu 300, Taiwan (China); Ren, F. [Department of Chemical Engineering, University of Florida, Gainesville, Florida 32611 (United States)

    2013-11-28

    The drain current fluctuation of ungated AlGaN/GaN high electron mobility transistors (HEMTs) measured in different fluids at a drain-source voltage of 0.5 V was investigated. The HEMTs with metal on the gate region showed good current stability in deionized water, while a large fluctuation in drain current was observed for HEMTs without gate metal. The fluctuation in drain current for the HEMTs without gate metal was observed and calculated as standard deviation from a real-time measurement in air, deionized water, ethanol, dimethyl sulfoxide, ethylene glycol, 1,2-butanediol, and glycerol. At room temperature, the fluctuation in drain current for the HEMTs without gate metal was found to be relevant to the dipole moment and the viscosity of the liquids. A liquid with a larger viscosity showed a smaller fluctuation in drain current. The viscosity-dependent fluctuation of the drain current was ascribed to the Brownian motions of the liquid molecules, which induced a variation in the surface dipole of the gate region. This study uncovers the causes of the fluctuation in drain current of HEMTs in fluids. The results show that the AlGaN/GaN HEMTs may be used as sensors to measure the viscosity of liquids within a certain range of viscosity.

  1. Is open surgery for head and neck cancers truly declining?

    NARCIS (Netherlands)

    Hartl, D.M.; Brasnu, D.F.; Shah, J.P.; Hinni, M.L.; Takes, R.P.; Olsen, K.D.; Kowalski, L.P.; Rodrigo, J.P.; Strojan, P.; Wolf, G.T.; Rinaldo, A.; Suarez, C.; Mendenhall, W.M.; Paleri, V.; Forastiere, A.A.; Werner, J.A.; Ferlito, A.

    2013-01-01

    In the past two decades, major modifications in the way we treat head and neck cancers, due to advances in technology and medical oncology, have led to a decline in the use of open surgery as first-line treatment of cancers arising from several primary tumor sites. The incidence of tobacco- and

  2. Head First Web Design

    CERN Document Server

    Watrall, Ethan

    2008-01-01

    Want to know how to make your pages look beautiful, communicate your message effectively, guide visitors through your website with ease, and get everything approved by the accessibility and usability police at the same time? Head First Web Design is your ticket to mastering all of these complex topics, and understanding what's really going on in the world of web design. Whether you're building a personal blog or a corporate website, there's a lot more to web design than div's and CSS selectors, but what do you really need to know? With this book, you'll learn the secrets of designing effecti

  3. Head First Python

    CERN Document Server

    Barry, Paul

    2010-01-01

    Ever wished you could learn Python from a book? Head First Python is a complete learning experience for Python that helps you learn the language through a unique method that goes beyond syntax and how-to manuals, helping you understand how to be a great Python programmer. You'll quickly learn the language's fundamentals, then move onto persistence, exception handling, web development, SQLite, data wrangling, and Google App Engine. You'll also learn how to write mobile apps for Android, all thanks to the power that Python gives you. We think your time is too valuable to waste struggling with

  4. Head first C#

    CERN Document Server

    Stellman, Andrew

    2010-01-01

    You want to learn C# programming, but you're not sure you want to suffer through another tedious technical book. You're in luck: Head First C# introduces this language in a fun, visual way. You'll quickly learn everything from creating your first program to learning sophisticated coding skills with C# 4.0, Visual Studio 2010 and .NET 4, while avoiding common errors that frustrate many students. The second edition offers several hands-on labs along the way to help you build and test programs using skills you've learned up to that point. In the final lab, you'll put everything together. From o

  5. Head first C#

    CERN Document Server

    Stellman, Andrew

    2008-01-01

    Head First C# is a complete learning experience for object-oriented programming, C#, and the Visual Studio IDE. Built for your brain, this book covers C# 3.0 and Visual Studio 2008, and teaches everything from language fundamentals to advanced topics including garbage collection, extension methods, and double-buffered animation. You'll also master C#'s hottest and newest syntax, LINQ, for querying SQL databases, .NET collections, and XML documents. By the time you're through, you'll be a proficient C# programmer, designing and coding large-scale applications. Every few chapters you will come

  6. Head First Mobile Web

    CERN Document Server

    Gardner, Lyza; Grigsby, Jason

    2011-01-01

    Despite the huge number of mobile devices and apps in use today, your business still needs a website. You just need it to be mobile. Head First Mobile Web walks you through the process of making a conventional website work on a variety smartphones and tablets. Put your JavaScript, CSS media query, and HTML5 skills to work-then optimize your site to perform its best in the demanding mobile market. Along the way, you'll discover how to adapt your business strategy to target specific devices. Navigate the increasingly complex mobile landscapeTake both technical and strategic approaches to mobile

  7. Fracture mapping of displaced partial articular fractures of the radial head

    NARCIS (Netherlands)

    Mellema, Jos J.; Eygendaal, Denise; van Dijk, C. Niek; Ring, David; Doornberg, Job N.

    2016-01-01

    Recognition of patterns of traumatic elbow instability helps anticipate specific fracture characteristics and associated injuries. The objective of this study was to assess the association of fracture line distribution and location of displaced partial articular radial head fractures with specific

  8. Comparison of sediment supply to San Francisco Bay from watersheds draining the Bay Area and the Central Valley of California

    Science.gov (United States)

    McKee, L.J.; Lewicki, M.; Schoellhamer, D.H.; Ganju, N.K.

    2013-01-01

    Quantifying suspended sediment loads is important for managing the world's estuaries in the context of navigation, pollutant transport, wetland restoration, and coastal erosion. To address these needs, a comprehensive analysis was completed on sediment supply to San Francisco Bay from fluvial sources. Suspended sediment, optical backscatter, velocity data near the head of the estuary, and discharge data obtained from the output of a water balance model were used to generate continuous suspended sediment concentration records and compute loads to the Bay from the large Central Valley watershed. Sediment loads from small tributary watersheds around the Bay were determined using 235 station-years of suspended sediment data from 38 watershed locations, regression analysis, and simple modeling. Over 16 years, net annual suspended sediment load to the head of the estuary from its 154,000 km2 Central Valley watershed varied from 0.13 to 2.58 (mean = 0.89) million metric t of suspended sediment, or an average yield of 11 metric t/km2/yr. Small tributaries, totaling 8145 km2, in the nine-county Bay Area discharged between 0.081 and 4.27 (mean = 1.39) million metric t with a mean yield of 212 metric t/km2/yr. The results indicate that the hundreds of urbanized and tectonically active tributaries adjacent to the Bay, which together account for just 5% of the total watershed area draining to the Bay and provide just 7% of the annual average fluvial flow, supply 61% of the suspended sediment. The small tributary loads are more variable (53-fold between years compared to 21-fold for the inland Central Valley rivers) and dominated fluvial sediment supply to the Bay during 10 out of 16 yr. If San Francisco Bay is typical of other estuaries in active tectonic or climatically variable coastal regimes, managers responsible for water quality, dredging and reusing sediment accumulating in shipping channels, or restoring wetlands in the world's estuaries may need to more carefully

  9. 46 CFR 7.70 - Folly Island, SC to Hilton Head Island, SC.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Folly Island, SC to Hilton Head Island, SC. 7.70 Section... BOUNDARY LINES Atlantic Coast § 7.70 Folly Island, SC to Hilton Head Island, SC. (a) A line drawn from the southernmost extremity of Folly Island to latitude 32°35′ N. longitude 79°58.2′ W. (Stono Inlet Lighted Whistle...

  10. production lines

    Directory of Open Access Journals (Sweden)

    Jingshan Li

    2000-01-01

    Full Text Available In this work, serial production lines with finished goods buffers operating in the pull regime are considered. The machines are assumed to obey Bernoulli reliability model. The problem of satisfying customers demand is addressed. The level of demand satisfaction is quantified by the due-time performance (DTP, which is defined as the probability to ship to the customer a required number of parts during a fixed time interval. Within this scenario, the definitions of DTP bottlenecks are introduced and a method for their identification is developed.

  11. Dissolved organic nitrogen (DON) losses from nested artificially drained lowland catchments with contrasting soil types

    Science.gov (United States)

    Tiemeyer, Bärbel; Kahle, Petra; Lennartz, Bernd

    2010-05-01

    Artificial drainage is a common practice to improve moisture and aeration conditions of agricultural land. It shortens the residence time of water in the soil and may therefore contribute to the degradation of peatlands as well as to the still elevated level of diffuse pollution of surface water bodies, particularly if flow anomalies like preferential flow cause a further acceleration of water and solute fluxes. Especially in the case of nitrate, artificially drained sub-catchments are found to control the catchment-scale nitrate losses. However, it is frequently found that nitrate losses and nitrogen field balances do not match. At the same time, organic fertilizers are commonly applied and, especially in lowland catchments, organic soils have been drained for agricultural use. Thus, the question arises whether dissolved organic nitrogen (DON) forms an important component of the nitrogen losses from artificially drained catchments. However, in contrast to nitrate and even to dissolved organic carbon (DOC), this component is frequently overlooked, especially in nested catchment studies with different soil types and variable land use. Here, we will present data from a hierarchical water quantity and quality measurement programme in the federal state Mecklenburg-Vorpommern (North-Eastern Germany). The monitoring programme in the pleistocene lowland catchment comprises automatic sampling stations at a collector drain outlet (4.2 ha catchment), at a ditch draining arable land on mineral soils (179 ha), at a ditch mainly draining grassland on organic soils (85 ha) and at a brook with a small rural catchment (15.5 km²) of mixed land use and soil types. At all sampling stations, daily to weekly composite samples were taken, while the discharge and the meteorological data were recorded continuously. Water samples were analyzed for nitrate-nitrogen, ammonium-nitrogen and total nitrogen. We will compare two years: 2006/07 was a very wet year (P = 934 mm) with a high summer

  12. Suction on chest drains following lung resection: evidence and practice are not aligned.

    Science.gov (United States)

    Lang, Peter; Manickavasagar, Menaka; Burdett, Clare; Treasure, Tom; Fiorentino, Francesca

    2016-02-01

    A best evidence topic in Interactive CardioVascular and Thoracic Surgery (2006) looked at application of suction to chest drains following pulmonary lobectomy. After screening 391 papers, the authors analysed six studies (five randomized controlled trials [RCTs]) and found no evidence in favour of postoperative suction in terms of air leak duration, time to chest drain removal or length of stay. Indeed, suction was found to be detrimental in four studies. We sought to determine whether clinical practice is consistent with published evidence by surveying thoracic units nationally and performing a meta-analysis of current best evidence. We systematically searched MEDLINE, EMBASE and CENTRAL for RCTs, comparing outcomes with and without application of suction to chest drains after lung surgery. A meta-analysis was performed using RevMan(©) software. A questionnaire concerning chest drain management and suction use was emailed to a clinical representative in every thoracic unit. Eight RCTs, published 2001-13, with 31-500 participants, were suitable for meta-analysis. Suction prolonged length of stay (weighted mean difference [WMD] 1.74 days; 95% confidence interval [CI] 1.17-2.30), chest tube duration (WMD 1.77 days; 95% CI 1.47-2.07) and air leak duration (WMD 1.47 days; 95% CI 1.45-2.03). There was no difference in occurrence of prolonged air leak. Suction was associated with fewer instances of postoperative pneumothorax. Twenty-five of 39 thoracic units responded to the national survey. Suction is routinely used by all surgeons in 11 units, not by any surgeon in 5 and by some surgeons in 9. Of the 91 surgeons represented, 62 (68%) routinely used suction. Electronic drains are used in 15 units, 10 of which use them routinely. Application of suction to chest drains following non-pneumonectomy lung resection is common practice. Suction has an effect in hastening the removal of air and fluid in clinical experience but a policy of suction after lung resection has not

  13. An approach for understanding the heredity of two quality traits (head color and tightness in globe artichoke (Cynara scolymus L.

    Directory of Open Access Journals (Sweden)

    Cravero Vanina Pamela

    2005-01-01

    Full Text Available The inheritance of head color and tightness in globe artichoke was studied utilizing crosses between inbreed lines and between clones and self-pollinated clones from different genetic origins. These genetic materials were sowed in a completely randomized design with 20 plants per plot and genotype. Globe artichoke heads were classified into three colors (purple-green, purple and green and three head tightness types (compact, fairly compact and soft and the segregating ratios for these traits tested in each offspring using the chi-square test. Crosses between green and purple inbreed lines produced only purple-green heads but F2 generation segregated at a purple-green:purple:green ratio of 9:3:4. The self-pollinated compact head clones produced a compact head:fairly compact head:soft head ratio of 12:3:1. The remaining crosses between lines and among clones and backcrosses verified these ratios. These results suggest that two loci with a simple recessive epistasis are involved in the inheritance of head color and that two loci with simple dominant epistasis are involved in the expression of the different head tightness types. The inheritance models proposed here could be helpful in predicting the appearance of artichoke heads if breeders need to obtain hybrid seeds for a desirable phenotype.

  14. Manual of head and neck imaging

    Energy Technology Data Exchange (ETDEWEB)

    Raghavan, Prashant [Maryland University School of Medicine, Baltimore, MD (United States). Div. of Neuroradiology; Mukherjee, Sugoto [Virginia University Health System, Charlottesville, VA (United States). Div. of Neuroradiology; Jameson, Mark J. [Virginia University Health System, Charlottesville, VA (United States). Div. of Head and Neck Surgical Oncology; Wintermark, Max [Virginia University Health System, Charlottesville, VA (United States). Dept. of Radiology and Medical Imaging

    2014-06-01

    Easy-to-read short chapters. Tables, checklists, and algorithms to assist in arriving at a quick diagnosis. Clinical pearls that will enable the radiologist to issue a relevant report. One-stop resource when preparing for radiology and otolaryngology exams. Line diagrams to illustrate key concepts. This book is designed as an easily readable manual that will be of great practical value for radiology and otolaryngology residents during their clinical rotations. Key facts on head and neck imaging are presented in short chapters written in an easily readable style. Line drawings are used to illustrate key concepts, and tables, checklists, and algorithms will enable the readers to arrive at a quick diagnosis. In addition, emphasis is placed on clinical pearls that will assist them in preparing suitable reports. The Manual of Head and Neck Imaging is sized to allow residents to read it completely within a matter of days, and it will also serve as an ideal quick reference guide as different clinical situations arise.

  15. HEADS UP : Sensorimotor control of the head-neck system

    NARCIS (Netherlands)

    Forbes, P.A.

    2014-01-01

    Head-neck stabilization is inherently challenging even when stationary, requiring constant vigilance to counter the downward pull of gravity. It involves a highly complex biomechanical system comprised of a large mass (the head) balanced on top of seven vertebrae (the neck), that are in turn

  16. Physicians' brain drain in Greece: a perspective on the reasons why and how to address it.

    Science.gov (United States)

    Ifanti, Amalia A; Argyriou, Andreas A; Kalofonou, Foteini H; Kalofonos, Haralabos P

    2014-08-01

    This review study explores the "brain drain" currently evident amongst physicians in Greece, which is closely linked to the country's severe financial woes. In particular, it shows that the Greek healthcare labour market offers few opportunities and thus physicians are forsaking their homeland to seek jobs abroad. The main causes generating or greatly inflating the brain drain of Greek physicians are unemployment, job insecurity, income reduction, over-taxation, together with limited budgets for research institutes. It is argued that, to stop the evolving mass exodus of skilled medical staff, policy-makers should implement fiscal and human-centred approaches, thoroughly safeguarding both the right of skilled Greek physicians to work in their homeland with motivation and dignity, but also of Greek citizens to continue receiving high-quality healthcare by skilled physicians at times when this is mostly needed. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  17. Catheters, wires, tubes and drains on postoperative radiographs of pediatric cardiac patients: the whys and wherefores

    Energy Technology Data Exchange (ETDEWEB)

    Teele, Sarah A.; Thiagarajan, Ravi R. [Children' s Hospital Boston, Department of Cardiology, Boston, MA (United States); Harvard Medical School, Department of Pediatrics, Boston, MA (United States); Emani, Sitaram M. [Children' s Hospital Boston, Department of Cardiac Surgery, Boston, MA (United States); Harvard Medical School, Department of Surgery, Boston, MA (United States); Teele, Rita L. [Harvard Medical School, Department of Radiology, Boston, MA (United States); Starship Children' s Hospital, Department of Radiology, Grafton (New Zealand)

    2008-10-15

    Surgical treatment of congenital heart disease has advanced dramatically since the first intracardiac repairs in the mid-20th century. Previously inoperable lesions have become the focus of routine surgery and patients are managed successfully in intensive care units around the world. As a result, increasing numbers of postoperative images are processed by departments of radiology in children's hospitals. It is important that the radiologist accurately documents and describes the catheters, wires, tubes and drains that are present on the chest radiograph. This article reviews the reasons for the placement and positioning of perioperative equipment in children who have surgical repair of atrial septal defect, ventricular septal defect or transposition of the great arteries. Also included are a brief synopsis of each cardiac anomaly, the surgical procedure for its correction, and an in-depth discussion of the postoperative chest radiograph including illustrations of catheters, wires, tubes and drains. (orig.)

  18. Enhancement-mode Ga2O3 MOSFETs with Si-ion-implanted source and drain

    Science.gov (United States)

    Wong, Man Hoi; Nakata, Yoshiaki; Kuramata, Akito; Yamakoshi, Shigenobu; Higashiwaki, Masataka

    2017-04-01

    Enhancement-mode β-Ga2O3 metal-oxide-semiconductor field-effect transistors with low series resistance were achieved by Si-ion implantation doping of the source/drain contacts and access regions. An unintentionally doped Ga2O3 channel with low background carrier concentration that was fully depleted at a gate bias of 0 V gave rise to a positive threshold voltage without additional constraints on the channel dimensions or device architecture. Transistors with a channel length of 4 µm delivered a maximum drain current density (I DS) of 1.4 mA/mm and an I DS on/off ratio near 106. Nonidealities associated with the Al2O3 gate dielectric as well as their impact on enhancement-mode device performance are discussed.

  19. Analytical drain current model for Gate and Channel Engineered RingFET (GCE-RingFET)

    Science.gov (United States)

    Kumar, Sachin; Kumari, Vandana; Singh, Sanjeev; Saxena, Manoj; Gupta, Mridula

    2017-11-01

    In this work, an analytical drain current model for Gate and Channel Engineered RingFET (GCE-RingFET) has been developed by solving 2D-Poisson equation in cylindrical coordinates. The authenticity of proposed model for GCE-RingFET architecture has been justified by comparing the analytical results with simulation results obtained using ATLAS 3D device simulation. Performance comparison of GCE-RingFET with the conventional RingFET device architectures has been performed. Various important performance metrics such as surface potential, transfer characteristic (Ids-Vgs), ION/IOFF ratio, Threshold voltage roll off, Sub-threshold Slope (SS), Drain Induced Barrier Lowering (DIBL), Trans-conductance Generation Efficiency (gm/Ids), have been investigated.

  20. Ubuntunet Alliance: A Collaborative Research Platform for Sharing of Technological Tools for Eradication of Brain Drain

    Directory of Open Access Journals (Sweden)

    Jameson Mbale

    2012-12-01

    Full Text Available The UbuntuNet Alliance Alliance is well-placed to facilitate interaction between education and research institutions and the African academic and researcher in the Diaspora so that together they can strengthen research that will exploit new technological tools and increase the industrial base. It is envisaged that the Alliance will become an important vehicle for linkages that will facilitate repatriation of scientific knowledge and skills to Africa and even help reduce and eventually eradicate the brain drain which has taken so many excellent intellectuals to the developed world. As organisational vehicles for inter-institutional collaboration both established and emerging NRENs can play a critical role in reversing these trends and in mitigating what appears to be the negative impact of the brain drain.

  1. Canine scent detection and microbial source tracking of human waste contamination in storm drains.

    Science.gov (United States)

    Van De Werfhorst, Laurie C; Murray, Jill L S; Reynolds, Scott; Reynolds, Karen; Holden, Patricia A

    2014-06-01

    Human fecal contamination of surface waters and drains is difficult to diagnose. DNA-based and chemical analyses of water samples can be used to specifically quantify human waste contamination, but their expense precludes routine use. We evaluated canine scent tracking, using two dogs trained to respond to the scent of municipal wastewater, as a field approach for surveying human fecal contamination. Fecal indicator bacteria, as well as DNA-based and chemical markers of human waste, were analyzed in waters sampled from canine scent-evaluated sites (urban storm drains and creeks). In the field, the dogs responded positively (70% and 100%) at sites for which sampled waters were then confirmed as contaminated with human waste. When both dogs indicated a negative response, human waste markers were absent. Overall, canine scent tracking appears useful for prioritizing sampling sites for which DNA-based and similarly expensive assays can confirm and quantify human waste contamination.

  2. Parallel Lines

    Directory of Open Access Journals (Sweden)

    James G. Worner

    2017-05-01

    Full Text Available James Worner is an Australian-based writer and scholar currently pursuing a PhD at the University of Technology Sydney. His research seeks to expose masculinities lost in the shadow of Australia’s Anzac hegemony while exploring new opportunities for contemporary historiography. He is the recipient of the Doctoral Scholarship in Historical Consciousness at the university’s Australian Centre of Public History and will be hosted by the University of Bologna during 2017 on a doctoral research writing scholarship.   ‘Parallel Lines’ is one of a collection of stories, The Shapes of Us, exploring liminal spaces of modern life: class, gender, sexuality, race, religion and education. It looks at lives, like lines, that do not meet but which travel in proximity, simultaneously attracted and repelled. James’ short stories have been published in various journals and anthologies.

  3. Brain Drain

    Directory of Open Access Journals (Sweden)

    Mark Cripsin Miller

    2006-04-01

    Full Text Available Ce texte, qui sera publié dans la revue Context (n°9 et que Mark Crispin Miller et l’éditeur nous ont généreusement permis de reproduire, est un papier d’humeur qui tente de relier deux aspects de la culture américaine, à savoir d’un côté la liberté de la parole « démocratique» auquel le médium d’internet a donné une nouvelle dimension, et de l’autre l’anti‑intellectualisme — vrai ou supposé — de cette même culture. En cela, il touche à un débat fondamental pour l’étude des Etats‑Unis. Ce premier numéro de TransatlanticA, du portrait de Tocqueville à la peinture américaine du XIXe siècle exposée à Giverny, lui fait une large place.

  4. Carbon dioxide flux from rice paddy soils in central China: effects of intermittent flooding and draining cycles.

    Science.gov (United States)

    Liu, Yi; Wan, Kai-yuan; Tao, Yong; Li, Zhi-guo; Zhang, Guo-shi; Li, Shuang-lai; Chen, Fang

    2013-01-01

    A field experiment was conducted to (i) examine the diurnal and seasonal soil carbon dioxide (CO(2)) fluxes pattern in rice paddy fields in central China and (ii) assess the role of floodwater in controlling the emissions of CO(2) from soil and floodwater in intermittently draining rice paddy soil. The soil CO(2) flux rates ranged from -0.45 to 8.62 µmol.m(-2).s(-1) during the rice-growing season. The net effluxes of CO(2) from the paddy soil were lower when the paddy was flooded than when it was drained. The CO(2) emissions for the drained conditions showed distinct diurnal variation with a maximum efflux observed in the afternoon. When the paddy was flooded, daytime soil CO(2) fluxes reversed with a peak negative efflux just after midday. In draining/flooding alternating periods, a sudden pulse-like event of rapidly increasing CO(2) efflux occured in response to re-flooding after draining. Correlation analysis showed a negative relation between soil CO(2) flux and temperature under flooded conditions, but a positive relation was found under drained conditions. The results showed that draining and flooding cycles play a vital role in controlling CO(2) emissions from paddy soils.

  5. Hydrology and Water Quality of a Drained Loblolly Pine Plantation in Coastal North Carolina

    Science.gov (United States)

    Devendra M. Amatya; R. W. Skaggs; J. W. Gilliam

    2006-01-01

    This paper evaluates 17 years (1988-2004) of hydrologic and water quality data from a drained pine plantation in eastern North Carolina. The plantation age was 14 years at the beginning of the investigation (1988) and 30 years at the end of (2004). The 17-year average rainfall of 1538 mm was 11% higher that the 50-year (1951 – 2000) long-term data of 1391 mm observed...

  6. Temperature dependence of drain-induced barrier lowering in deep submicrometre MOSFETs

    Science.gov (United States)

    Fikry, W.; Ghibaudo, G.; Dutoit, M.

    1994-05-01

    A new method for extracting the drain-induced barrier lowering (DIBL) parameter in an MOS transistor is proposed. This method is used to study the influence of temperature on the DIBL effect. It is found that the DIBL parameter is almost independent of temperature between 50 and 300 K. This method also makes it possible to recalculate the intrinsic output characteristics that the device would have in the absence of DIBL, and, in turn, to evaluate the intrinsic device saturation parameters.

  7. Developing Science: Scientific Performance and Brain Drains in the Developing World

    OpenAIRE

    Weinberg, Bruce A.

    2011-01-01

    Establishing a strong scientific community is important as countries develop, which requires both producing and retaining of important scientists. We show that developing countries produce a sizeable number of important scientists, but that they experience a tremendous brain drain. Education levels, population, and per capita GDP are positively related to the number of important scientists born in and staying in a country. Our analysis indicates that democracy and urbanization are associated ...

  8. Lawps ion exchange column gravity drain of spherical resorcinol formaldehyde resin

    Energy Technology Data Exchange (ETDEWEB)

    Duignan, M. R. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Herman, D. T. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Restivo, M. L. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Burket, P. R. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-01-28

    Experiments at several different scales were performed to understand the removal of spherical resorcinol formaldehyde (sRF) ion exchange resin using a gravity drain system with a valve located above the resin screen in the ion exchange column (IXC). This is being considered as part of the design for the Low Activity Waste Pretreatment System (LAWPS) to be constructed at the DOE Hanford Site.

  9. Bilateral superior vena cava with right superior vena cava draining into left atrium.

    Science.gov (United States)

    Alghamdi, Mohammed H; Elfaki, Wafa; Al-Habshan, Fahad; Aljarallah, Abdullah S

    2015-04-01

    Anomalies of systemic venous return are extremely heterogeneous congenital malformations with variable ranges from completely normal physiology to severe forms of right to left shunting requiring surgical treatment. Anomalous drainage of a right-sided superior vena cava (SVC) to the left atrium (LA) is one of the rarest variants of systemic venous return anomalies, characterized by right-to-left shunt physiology and cyanosis. Here we report a 2 years old girl presented with cyanosis which was observed shortly after birth by her parents but not further investigated. She is otherwise active girl and with normal growth and development. Her clinical examination was unremarkable apart from mild clubbing of the fingers and low oxygen saturation of 88-90% in room air. Her ECG and chest X-ray were unremarkable. Echocardiography showed bilateral SVC connected by a small innominate vein. The right SVC drains directly into the LA while the left SVC drains into the right atrium (RA) via a dilated coronary sinus. There is a small superior sinus venosus type atrial septum defect (ASD) with left to right shunt. Also, there is partial anomalous pulmonary venous return with right upper and right middle pulmonary veins draining directly into the right SVC, which is connected to LA. The right lower pulmonary vein and left pulmonary veins drain directly to LA. The rest of her echocardiography demonstrated normal heart structures and function. This patient was referred for surgical correction, including baffling of the right SVC to the RA and closure of the ASD. We describe this case to highlight the importance of recognizing this rare anomalous systemic venous connection as one of the very rare causes of cyanosis in the pediatric age group as well as at older age.

  10. Managing health worker migration: a qualitative study of the Philippine response to nurse brain drain

    Directory of Open Access Journals (Sweden)

    Dimaya Roland M

    2012-12-01

    Full Text Available Abstract Background The emigration of skilled nurses from the Philippines is an ongoing phenomenon that has impacted the quality and quantity of the nursing workforce, while strengthening the domestic economy through remittances. This study examines how the development of brain drain-responsive policies is driven by the effects of nurse migration and how such efforts aim to achieve mind-shifts among nurses, governing and regulatory bodies, and public and private institutions in the Philippines and worldwide. Methods Interviews and focus group discussions were conducted to elicit exploratory perspectives on the policy response to nurse brain drain. Interviews with key informants from the nursing, labour and immigration sectors explored key themes behind the development of policies and programmes that respond to nurse migration. Focus group discussions were held with practising nurses to understand policy recipients’ perspectives on nurse migration and policy. Results Using the qualitative data, a thematic framework was created to conceptualize participants’ perceptions of how nurse migration has driven the policy development process. The framework demonstrates that policymakers have recognised the complexity of the brain drain phenomenon and are crafting dynamic policies and programmes that work to shift domestic and global mindsets on nurse training, employment and recruitment. Conclusions Development of responsive policy to Filipino nurse brain drain offers a glimpse into a domestic response to an increasingly prominent global issue. As a major source of professionals migrating abroad for employment, the Philippines has formalised efforts to manage nurse migration. Accordingly, the Philippine paradigm, summarised by the thematic framework presented in this paper, may act as an example for other countries that are experiencing similar shifts in healthcare worker employment due to migration.

  11. Managing health worker migration: a qualitative study of the Philippine response to nurse brain drain.

    Science.gov (United States)

    Dimaya, Roland M; McEwen, Mary K; Curry, Leslie A; Bradley, Elizabeth H

    2012-12-19

    The emigration of skilled nurses from the Philippines is an ongoing phenomenon that has impacted the quality and quantity of the nursing workforce, while strengthening the domestic economy through remittances. This study examines how the development of brain drain-responsive policies is driven by the effects of nurse migration and how such efforts aim to achieve mind-shifts among nurses, governing and regulatory bodies, and public and private institutions in the Philippines and worldwide. Interviews and focus group discussions were conducted to elicit exploratory perspectives on the policy response to nurse brain drain. Interviews with key informants from the nursing, labour and immigration sectors explored key themes behind the development of policies and programmes that respond to nurse migration. Focus group discussions were held with practising nurses to understand policy recipients' perspectives on nurse migration and policy. Using the qualitative data, a thematic framework was created to conceptualize participants' perceptions of how nurse migration has driven the policy development process. The framework demonstrates that policymakers have recognised the complexity of the brain drain phenomenon and are crafting dynamic policies and programmes that work to shift domestic and global mindsets on nurse training, employment and recruitment. Development of responsive policy to Filipino nurse brain drain offers a glimpse into a domestic response to an increasingly prominent global issue. As a major source of professionals migrating abroad for employment, the Philippines has formalised efforts to manage nurse migration. Accordingly, the Philippine paradigm, summarised by the thematic framework presented in this paper, may act as an example for other countries that are experiencing similar shifts in healthcare worker employment due to migration.

  12. Network theory: key issues for the analysis of the "brain drain"

    Directory of Open Access Journals (Sweden)

    Diana Carolina Henao

    2012-12-01

    Full Text Available This paper offers an analysis of the brain drain from the perspective of the network theory. Some definitions and key concepts of the network theory have been discussed in relation to criteria and reasons that are taken into account by people with broad educational capital from developing countries who are involved in the research in different areas of knowledge and who seek to adapt to other scientific collaboration networks in the developed countries.

  13. Denial of student visas leads to brain drain from university research

    CERN Multimedia

    Wertheimer, L K

    2002-01-01

    America's move to shut the gate on student visas after the terrorist attack on the Twin Towers, has created a brain drain for universities that rely on top foreign students to help with scientific research. Professors, graduate school deans and officials from national science societies say hundreds of foreign students recruited to work on projects in such areas as physics, math and petroleum engineering they couldn't get visas this fall. Some gave up and went to other countries instead (2 pages).

  14. Variations in Draining Patterns of Right Pulmonary Veins at the Hilum and an Anatomical Classification

    OpenAIRE

    Rajeshwari, M. S.; Ranganath, Priya

    2012-01-01

    Pulmonary veins carry oxygenated blood from the lungs to the left atrium. Variations are quite common in the pattern of drainage. The present study was undertaken to evaluate the incidence of different draining patterns of the right pulmonary veins at the hilum by dissecting the human fixed cadaveric lungs. Clinically, pulmonary veins have been demonstrated to often play an important role in generating atrial fibrillation. Hence, it is important to look into the anatomy of the veins during MR...

  15. Giant Right Coronary Artery Aneurysm Associated with a Fistula Draining into the Superior Vena Cava.

    Science.gov (United States)

    Dolapoglu, Ahmet; Ott, David A

    2016-08-01

    Giant coronary artery aneurysm associated with a coronary-cameral fistula is an uncommon condition. Such aneurysms are usually associated with other cardiac diseases, such as coronary atherosclerosis, and therefore might augment myocardial ischemia in adults. The main indications for surgical intervention are severe coexisting coronary artery disease, evidence of embolization, and aneurysmal enlargement or rupture. We describe a large right coronary artery aneurysm and a coronary-cameral fistula that drained into the superior vena cava. The surgical repair was successful.

  16. THE EFFECTS OF AN INCENTIVE MECHANISM ON BRAIN DRAIN IN THE HOTEL INDUSTRY

    OpenAIRE

    Zhao, Danni

    2016-01-01

    This thesis studies the effects of incentive mechanism on brain drain in hotel industry. As for the reason why this topic is chosen, it is regarding to the author's previous working experiences in the hotel industry. After the training practice in several different hotels, it is notable that Chinese hotel industry is confronted with a severe problem of high employee turnover. While the normal human resource turnover rate should remain between 5% and 10%, the average figure for the hotel staff...

  17. Efficacy of tranexamic acid plus drain-clamping to reduce blood loss in total knee arthroplasty: A meta-analysis.

    Science.gov (United States)

    Zhang, Yan; Zhang, Jun-Wei; Wang, Bao-Hua

    2017-06-01

    Perioperative blood loss is still an unsolved problem in total knee arthroplasty (TKA). The efficacy of the preoperative use of tranexamic acid (TXA) plus drain-clamping to reduce blood loss in TKA has been debated. This meta-analysis aimed to illustrate the efficacy of TXA plus drain-clamping to reduce blood loss in patients who underwent a TKA. In February 2017, a systematic computer-based search was conducted in PubMed, EMBASE, Web of Science, the Cochrane Database of Systematic Reviews, and Google Scholar. Data from patients prepared for TKA in studies that compared TXA plus drain-clamping versus TXA alone, drain-clamping alone, or controls were retrieved. The primary endpoint was the need for transfusion. The secondary outcomes were total blood loss, blood loss in drainage, the decrease in hemoglobin, and the occurrence of deep venous thrombosis. After testing for publication bias and heterogeneity between studies, data were aggregated for random-effects models when necessary. Ultimately, 5 clinical studies with 618 patients (TXA plus drain-clamping group = 249, control group = 130, TXA-alone group = 60, and drain-clamping group = 179) were included. TXA plus drain-clamping could decrease the need for transfusion, total blood loss, blood loss in drainage, and the decrease in hemoglobin than could the control group, the TXA-alone group, and the drain-clamping group (P  .05). TXA plus drain-clamping can achieve the maximum effects of hemostasis in patients prepared for primary TKA. Because the number and the quality of the included studies were limited, more high-quality randomized controlled trials are needed to identify the optimal dose of TXA and the clamping hours in patients prepared for TKA.

  18. Suction drains in esthetic breast implant exchange are associated with surgical site infections: A retrospective cohort study.

    Science.gov (United States)

    Hadad, Eran; Wiser, Itay; Rosenthal, Adaya; Landau, Geva; Ziv, Ella; Heller, Lior

    2017-11-01

    Surgical site infection (SSI) following esthetic breast implant exchange occurs in up to 2% of procedures. The effect of suction drains on SSI risk in these cases remains controversial. This study aimed to assess the SSI risk in the presence of suction drains after esthetic exchange of breast implants. This is a retrospective cohort study of patients undergoing esthetic breast implant exchange between 2012 and 2015. SSI was determined according to the definition of the Center for Disease Control and Prevention. Multivariate analysis using a logistic regression model to identify independent risk factors for SSI was performed. A total of 256 women (504 breasts) met the inclusion criteria and were included in the study. The mean age was 44 ± 11 years. The mean operative time was 93 ± 40 min. The mean implant age at the time of the exchange was 10.3 ± 6.5 years. Suction drains were used in 229 breasts (45.4%) and were removed after 6 ± 7 days. Twenty (4%) breasts were diagnosed with SSI, of which 17 had suction drains. Suction drain use and days until drain removal were associated with a higher risk of SSI (85.0% vs. 43.8%, p suction drains remained an independent risk factor for SSI after adjustment for age, smoking, and previous capsular contracture (OR = 10.66, CI 95% 2.42-46.82). Suction drain use in esthetic breast implant exchange is associated with an increased risk of SSI. Surgeons should carefully consider using suction drains in selected cases only. Copyright © 2017 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

  19. Si nanowire p-FET with asymmetric source-drain I-V characteristics

    Science.gov (United States)

    Lee, Sang-Kwon; Lee, Seung-Yong; Rogdakis, Konstantinos; Jang, Chan-Oh; Kim, Dong-Joo; Bano, Edwige; Zekentes, Konstantinos

    2009-03-01

    We report on the electrical characteristics and the effects of source/drain Schottky barrier heights (SBHs) in a lightly implanted silicon nanowire field-effect transistor (SiNW FET). We prepared the SiNW FETs by boron implantation with a dose of 1×10 12 ions/cm 2 and an energy of 10 keV. Our results indicated that the nature of the metal-contacts on the source/drain electrodes had a significant impact on the current-voltage characteristics for B-implanted SiNW FETs. The current-voltage (ID-V) characteristics for the B-implanted SiNW FETs with a symmetric IV behavior exhibited a clear p-channel FET behavior with a field-effect mobility of ˜0.4 cm 2/V s and a hole concentration of ˜1.7×10 17 cm -3. A 2D ATLAS simulation (SILVACO Inc.) with two different Schottky barrier heights of source/drain contacts to the SiNW supported the experimental results well.

  20. Antimony retention and release from drained and waterlogged shooting range soil under field conditions.

    Science.gov (United States)

    Hockmann, Kerstin; Tandy, Susan; Lenz, Markus; Reiser, René; Conesa, Héctor M; Keller, Martin; Studer, Björn; Schulin, Rainer

    2015-09-01

    Many soils polluted by antimony (Sb) are subject to fluctuating waterlogging conditions; yet, little is known about how these affect the mobility of this toxic element under field conditions. Here, we compared Sb leaching from a calcareous shooting range soil under drained and waterlogged conditions using four large outdoor lysimeters. After monitoring the leachate samples taken at bi-weekly intervals for >1.5 years under drained conditions, two of the lysimeters were subjected to waterlogging with a water table fluctuating according to natural rainfall water infiltration. Antimony leachate concentrations under drained conditions showed a strong seasonal fluctuation between 110 μg L(-1) in summer and Antimony speciation measurements in soil solution indicated that this decrease in Sb(V) concentrations was attributable to the reduction of Sb(V) to Sb(III) and the stronger sorption affinity of the latter to iron (Fe) (hydr)oxide phases. Our results demonstrate the importance of considering seasonal and waterlogging effects in the assessment of the risks from Sb-contaminated sites. Copyright © 2014 Elsevier Ltd. All rights reserved.

  1. Sediment and Nutrient Contributions from Subsurface Drains and Point Sources to an Agricultural Watershed

    Directory of Open Access Journals (Sweden)

    Bonnie Ball Coelho

    2010-03-01

    Full Text Available Excess sediment and nutrients in surface waters can threaten aquatic life. To determine the relative importance of subsurface drainage as a pathway for movement of sediment and nutrients to surface waters, loading from various tile systems was compared to that from sewage treatment plants (STP within the same watershed. Movement through tiles comprised 1 to 8% of estimated total (overland plus tile annual sediment loading from the respective areas drained by the tile. Load during the growing season from five closed drain- age systems without surface inlets averaged 5 kg sediment/ha, 0.005 kg dissolved reactive P (DRP/ha, 0.003 kg NH4-N/ha, and 3.8 kg NO3-N/ha; and from two open drainage systems with surface inlets averaged 14 kg sediment/ha, 0.03 kg DRP/ha, 0.04 kg NH4-N/ha, and 3.1 kg NO3-N/ha. The eight STP contributed about 44 530 kg suspended sediments, 3380 kg total P, 1340 kg NH4-N, and 116 900 kg NO3-N to the watershed annually. Drainage systems added less NH4-N and P, but more NO3-N and suspended solids to surface waters than STP. Tile drainage pathways for NO3-N, STP in the case of P, and overland pathways for sediment are indicated as targets to control loading in artificially drained agricultural watersheds.

  2. CMOS Application of Schottky Source/Drain SOI MOSFET with Shallow Doped Extension

    Science.gov (United States)

    Matsumoto, Sumie; Nishisaka, Mika; Asano, Tanemasa

    2004-04-01

    The silicon-on-insulator metal-oxide-semiconductor field-effect transistor (SOI MOSFET) whose source/drain is composed of Schottky contacts and a shallow-doped extension is investigated. It is demonstrated that the incorporation of the shallow-doped extension into the Schottky source/drain can increase the current drive and reduce the leakage current under reverse bias for both n-channel and p-channel devices. The shallow doping is performed by implanting Sb for n-channel devices, and BF2 or Ga for p-channel devices. The effect of Schottky contacts on the floating body effect (FBE) is investigated by analyzing the lateral bipolar characteristics of these devices. By employing the shallow-doped extension, a complementary MOS (CMOS) of the Schottky source/drain can be fabricated using single metal (cobalt, in this work) silicide. The stability of CMOS operation with the proposed devices under a high supply voltage is demonstrated by comparing it with a conventional pn-junction SOI MOSFET. It is also demonstrated from the characteristics of the CMOS-inverter ring oscillator that the proposed device operates at speeds as high as or even higher than that of the conventional SOI MOSFET.

  3. [Telescience : Feasibility studies, definition and a fair answer to the scientific brain drain].

    Science.gov (United States)

    Craemer, E M; Bassa, B; Jacobi, C; Becher, H; Meyding-Lamadé, U

    2017-02-01

    What is telescience? Is it feasible to transfer academic information with the help of telematics to educate and teach young scientists over large distances? The term telescience has so far not been defined but covers a variety of possibilities, which could be successfully implemented worldwide. This article gives examples and highlights the feasibility analysis of telescience. We have carried out feasibility analyses for neurological functional diagnostics, an epidemiological cross-sectional study as well as a laboratory study for detection of thrombocyte function during dengue fever with the help of telemedicine. The basis for all these projects was a telemedical transcontinental cooperation over a distance of 12,000 km. All performed studies demonstrated the feasibility. With the help of telematics the laboratory techniques, planning, conduction and interpretation of results as well as publication skills can be transferred. Telescience is feasible. Our studies showed that telescience is a very promising option to transfer knowledge, which will help to enable professional expertise to be transferred directly to the region/country without a brain drain. All too often young motivated scientists are enticed to move to well-known institutions, which involves the danger of a brain drain. Brain drain can be avoided in favor of local implementation of scientific projects. Our results illustrate that it is feasible to educate and guide scientists with the help of telematics infrastructures.

  4. The "brain drain" of health care workers: causes, solutions and the example of Jamaica.

    Science.gov (United States)

    Lofters, Aisha K

    2012-07-18

    Despite much media attention being given to the physician shortage in Canada in recent years, this shortage pales in comparison to that seen in many middle- and low-income countries. A major cause of the shortage in these countries is the migration of health care workers from developing to developed nations, a phenomenon known as the "brain drain". The loss of these workers is having devastating impacts globally, particularly in Sub-Saharan Africa and the Caribbean. Causes of the "brain drain" are numerous and include poor working conditions in poorer countries and active recruitment by richer countries. Jamaica has been one of the countries in the Caribbean hardest hit by mass migration of health care workers. The multiple dimensions of Jamaica's health worker "brain drain" illustrate both the complexity of the issues reviewed in this commentary, and the net loss for low- and middle-income countries. Creative and sustainable solutions to the problem are actively being sought globally, but will require commitment and support from all nations as well as from international funding bodies if meaningful impacts on health are to be realized.

  5. Stable carbon and nitrogen isotopes in vertical peat profiles of natural and drained boreal peatlands

    Science.gov (United States)

    Nykänen, Hannu; Mpamah, Promise; Rissanen, Antti; Pitkänen, Aki; Turunen, Jukka; Simola, Heikki

    2015-04-01

    Peatlands form a significant carbon pool in the global carbon cycle. Change in peat hydrology, due to global warming is projected to change microbiological processes and peat carbon pool. We tested if bulk stable carbon and nitrogen isotopes serve as indicators of severe long term drying in peatlands drained for forestry. Depth profile analysis of peat, for their carbon and nitrogen content as well as their carbon and nitrogen stable isotopic signatures, were conducted for peatlands in southern and eastern Finland, having ombrotrophic and minerotrophic natural and corresponding drained pairs or separate drained sites. The selection of sites allowed us to compare changes due to different fertility and changes due to long term artificial drying. Drainage lasting over 40 years has led to changes in hydrology, vegetation, nutrient mineralization and respiration. Furthermore, increased nutrient uptake and possible recycling of peat nitrogen and carbon trough vegetation back to the peat surface, also possibly has an effect on the stable isotopic composition of peat carbon and nitrogen. We think that drainage induced changes somehow correspond to those caused by changed hydrology due to climate change. We will present data from these measurements and discuss their implications for carbon and nitrogen flows in peatlands.

  6. Correlation between ATLS training and junior doctors' anatomical knowledge of intercostal chest drain insertion.

    Science.gov (United States)

    Kong, Victor Y; Oosthuizen, George V; Sartorius, Benn; Keene, Claire M; Clarke, Damian L

    2015-01-01

    To review the ability of junior doctors (JDs) in identifying the correct anatomical site for intercostal chest drain insertion and whether prior Advanced Trauma Life Support (ATLS) training influences this. We performed a prospective, observational study using a structured survey and asked a group of JDs (postgraduate year 1 [PGY1] or year 2 [PGY2]) to indicate on a photograph the exact preferred site for intercostal chest drain insertion. This study was conducted in a large metropolitan university hospital in South Africa. A total of 152 JDs participated in the study. Among them, 63 (41%) were men, and the mean age was 24 years. There were 90 (59%) PGY1 doctors and 62 (41%) PGY2 doctors. Overall, 28% (42/152) of all JDs correctly identified the site that was located within the accepted safe triangle. A significantly higher proportion of PGY2 doctors selected the correct site when compared with PGY1 doctors (39% vs 20%, p = 0.026). Those who had prior ATLS provider training were 6.8 times more likely to be able to identify the correct site (RR = 6.8, 95% CI: 3.7-12.5). Most of the JDs do not have sufficient anatomical knowledge to identify the safe insertion site for intercostal chest drain. Those who had undergone ATLS training were more likely to be able to identify the safe insertion site. Copyright © 2015 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

  7. Draining T-Tube Jejunostomy: A Technique to Get Out of Trouble.

    Science.gov (United States)

    Serrano, Oscar K; Solsky, Ian; Sandoval, Eduardo; Berlin, Arnold; Bellemare, Sarah

    2016-06-01

    A perforated viscus in the postpancreaticoduodenectomy setting is a rare phenomenon and a devastating complication. In this situation, adherence to damage-control principles demands minimizing the operative intervention while addressing the intestinal perforation as a way to mitigate the injurious effects on a complex gastrointestinal reconstruction. Herein, we describe our intraoperative decision-making with an unconventional approach in the management of a perforated viscus in the postpancreaticoduodenectomy setting using a draining T-tube jejunostomy. Our patient recovered remarkably well from this and was discharged from the hospital in six days with a controlled draining T-tube jejunostomy, which was subsequently removed on postoperative day 35. Our case illustrates an important option when dealing with a perforated viscus in the complex gastrointestinal surgery patient that has minimal morbidity, adequate source control, and the potential for an excellent clinical outcome. As surgical care continues to be delivered in a specialty-driven manner, a draining T-tube jejunostomy presents the ideal technique to get out of trouble for the general surgeon practicing in the community who may not be as experienced with complex gastrointestinal surgery.

  8. Wound healing without drains in posterior spinal fusion in idiopathic scoliosis.

    Science.gov (United States)

    Alsiddiky, Abdulmonem; Nisar, Kaleem Ahmed; Alhuzaimi, Fahad; Albishi, Waleed; Alnuaim, Bader; Albarrag, Mohammed; Bakarman, Khalid; Meo, Sultan Ayoub

    2013-08-01

    To determine the frequency of wound infection and neurological injuries in patients with idiopathic scoliosis who underwent posterior spinal fusion without use of drains. Case series. Department of Orthopaedics, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia, from February 2007 to June 2010. Patients who underwent similar technique of posterior spinal fusion instrumentation for the correction of scoliosis without use of drain were included. Wound Demographics, wound healing, complications and duration of hospital stay were considered and described as frequency and mean values. The average age at the time of surgery was 12.80 ± 1.30 years, duration of surgery was 3.80 ± 0.86 hours, hospital stay was 3.84 ± 0.78 days and patients were followed-up over the last 30 months. There was no incidence of any neurological complication and deep infection. However, only 2 (4.16%) cases with superficial skin infection were treated with dressing and antibiotics with full recovery. The wound healing is adequate without using drain for patients with idiopathic scoliosis who underwent posterior spinal fusion and instrumentation when good wash, watertight closure technique and appropriate antibiotics coverage is provided.

  9. The health effects of swimming in ocean water contaminated by storm drain runoff.

    Science.gov (United States)

    Haile, R W; Witte, J S; Gold, M; Cressey, R; McGee, C; Millikan, R C; Glasser, A; Harawa, N; Ervin, C; Harmon, P; Harper, J; Dermand, J; Alamillo, J; Barrett, K; Nides, M; Wang, G

    1999-07-01

    Waters adjacent to the County of Los Angeles (CA) receive untreated runoff from a series of storm drains year round. Many other coastal areas face a similar situation. To our knowledge, there has not been a large-scale epidemiologic study of persons who swim in marine waters subject to such runoff. We report here results of a cohort study conducted to investigate this issue. Measures of exposure included distance from the storm drain, selected bacterial indicators (total and fecal coliforms, enterococci, and Escherichia coli), and a direct measure of enteric viruses. We found higher risks of a broad range of symptoms, including both upper respiratory and gastrointestinal, for subjects swimming (a) closer to storm drains, (b) in water with high levels of single bacterial indicators and a low ratio of total to fecal coliforms, and (c) in water where enteric viruses were detected. The strength and consistency of the associations we observed across various measures of exposure imply that there may be an increased risk of adverse health outcomes associated with swimming in ocean water that is contaminated with untreated urban runoff.

  10. Simulation and Experimentation for Low Density Drain AlGaN/GaN HEMT

    Science.gov (United States)

    Wang, Chong; He, Yun-Long; Ding, Ning; Zheng, Xue-Feng; Zhang, Peng; Ma, Xiao-Hua; Zhang, Jin-Cheng; Hao, Yue

    2014-03-01

    In order to improve the breakdown voltage of AlGaN/GaN high electron mobility transistors (HEMTs), we report a feasible method of low density drain (LDD) HEMT. The fluoride-based plasma treatment using CF4 gas is performed on the drain-side of the gate edge. The channel two-dimensional electron gas (2DEG) concentrations are modulated by fluoride plasma treatment, and the peak electric field at the gate edge is effectively reduced, so the breakdown voltage is improved. The electric field distributions of the LDD-HEMTs are simulated using the Silvaco software, and the peak of the electric field on the gate edge is effectively reduced. Experimental results show that, compared with the conventional HEMT, LDD-HEMTs have a lower reverse leakage current of the gate, and the breakdown voltage is increased by 36%. The current collapse characteristics of the LDD-HEMTs are confirmed by dual-pulse measurement, and an obvious pulse current reduction is due to the surface states by implanting F ions between the gate and the drain.

  11. Antibiogram profie of Pseudomonas aeruginosa isolated from some selected hospital environmental drains

    Directory of Open Access Journals (Sweden)

    Ekioba Olohigbe Imanah

    2017-10-01

    Full Text Available Objective: To isolate, identify and characterize Pseudomonas aeruginosa (P. aeruginosa from hospital drains using culture-based and PCR methods. Methods: Wastewater samples were obtained from hospital drains between August and October, 2015, using standard culture-based methods for isolation of P. aeruginosa. The isolates were further confirmed by specie-specific primer sets. Antimicrobial susceptibility testing of the isolates was conducted using the Kirby-Bauer disc diffusion method. Results: The mean P. aeruginosa population densities were expressed ranging between (1.7 × 105 ± 0.1 and (6.1 × 105 ± 0.2 CFU/mL. The antimicrobial susceptibility profile of the P. aeruginosa isolates revealed that all the isolates 96/96 (100% were resistant to penicillins (amoxicillin and cloxacillin as well as penicillin/β-lactamase inhibitor (augmentin while sensitivity was observed in carbapenems [imipenem 96/96 (100%]. The multiple antimicrobial resistance index of the P. aeruginosa to the antimicrobials used ranged from 0.33 to 0.89 while the multidrug resistant profile revealed resistance to augmentin, amoxicillin, cloxacillin. Conclusions: The present study reveals that hospital drains are potential reservoirs of multiple antibiotic resistances of P. aeruginosa.

  12. Carbon storage change in a partially forestry-drained boreal mire determined through peat column inventories

    Energy Technology Data Exchange (ETDEWEB)

    Pitkanen, A.; Tahvanainen, T.; Simola, H. [Univ. of Eastern Finland, Joensuu (Finland). Dept. pf Biology; Turunen, J. [Geological Survey of Finland, Kuopio (Finland)

    2013-09-01

    To study the impact of forestry drainage on peat carbon storage, we cored paired quantitative peat samples from undrained and drained sides of an eccentric bog. Five pairs of 0 to {<=} 100-cm-deep surface-peat cores, and a pair of profiles representing the full peat deposit provided stratigraphic evidence of marked loss of surface peat due to drainage. For the drained side cores, we found a relative subsidence of 25-37 cm of the surface, and a loss of about 10 kg{sub DW}{sup m-2}, corresponding to 131 {+-} 28 g C m{sup -2} a{sup -1} (mean {+-} SE) for the post-drainage period. Similar peat loss was also found in the full deposit profiles, thus lending credibility to the whole-column inventory approach, even though the decrease (9 kg{sub DW} m{sup -2}) was relatively small in comparison with the total carbon storage (233 and 224 kg{sub DW} m{sup -2} for the undrained and drained sides, respectively). (orig.)

  13. Un método alternativo para fijar drenajes An alternative way to secure drains

    Directory of Open Access Journals (Sweden)

    F. Solesio Pilarte

    2009-09-01

    Full Text Available La colocación de drenajes en las intervenciones quirúrgicas es una práctica muy habitual en la mayoría de las operaciones de Cirugía Plástica y también de otras especialidades, pero en ocasiones su objetivo fracasa al deslizarse el drenaje. Diversos autores han propuesto varios métodos de sujeción de los drenajes a la piel con distinto grado de aceptación. El más empleado es el método de "sandalia romana" que, si no se realiza correctamente resulta ineficaz. En el presente artículo analizamos dónde y por qué falla frecuentemente dicho método y proponemos un procedimiento alternativo, sencillo y seguro para la fijación de drenajes quirúrgicos, el uso del ballestrinque.Using drains in Plastic Surgery and other specialties is a very common practice. Sometimes the procedure fails when drains slide. Several securing methods have been reported in literature by authors with different grades of acceptance. The most commonly used one is the "roman sandal tying up", which results useless if not done correctly. For this reason we decided to analyze where and why such a method fails and propose an alternative, easy and trustable method to secure surgical drains: the clove hitch knot.

  14. Womanhood in Bessie Head's fiction

    African Journals Online (AJOL)

    confronted with gender discrimination in addition ;to the racial and ethnic marginality she had suffered since childhood. When the discovery of. Margaret's Basarwa origins culminate in the decision to get rid of her, Head points to the multiplicity of her problems. Head demonstrates that Margaret's womanhood comes into ...

  15. Analytical modelling of soccer heading

    Indian Academy of Sciences (India)

    Heading occur frequently in soccer games and studies have shown that repetitive heading of the soccer ball could result in degeneration of brain cells and lead to mild traumatic brain injury. This study proposes a two degree-of-freedom linear mathematical model to study the impact of the soccer ball on the brain. The model ...

  16. The head-mounted microscope.

    Science.gov (United States)

    Chen, Ting; Dailey, Seth H; Naze, Sawyer A; Jiang, Jack J

    2012-04-01

    Microsurgical equipment has greatly advanced since the inception of the microscope into the operating room. These advancements have allowed for superior surgical precision and better post-operative results. This study focuses on the use of the Leica HM500 head-mounted microscope for the operating phonosurgeon. The head-mounted microscope has an optical zoom from 2× to 9× and provides a working distance from 300 mm to 700 mm. The headpiece, with its articulated eyepieces, adjusts easily to head shape and circumference, and offers a focus function, which is either automatic or manually controlled. We performed five microlaryngoscopic operations utilizing the head-mounted microscope with successful results. By creating a more ergonomically favorable operating posture, a surgeon may be able to obtain greater precision and success in phonomicrosurgery. Phonomicrosurgery requires the precise manipulation of long-handled cantilevered instruments through the narrow bore of a laryngoscope. The head-mounted microscope shortens the working distance compared with a stand microscope, thereby increasing arm stability, which may improve surgical precision. Also, the head-mounted design permits flexibility in head position, enabling operator comfort, and delaying musculoskeletal fatigue. A head-mounted microscope decreases the working distance and provides better ergonomics in laryngoscopic microsurgery. These advances provide the potential to promote precision in phonomicrosurgery. Copyright © 2011 The American Laryngological, Rhinological, and Otological Society, Inc.

  17. 49 CFR 572.112 - Head assembly.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Head assembly. 572.112 Section 572.112... 50th Percentile Male § 572.112 Head assembly. The head assembly consists of the head (drawing 78051-61X...) accelerometers that are mounted in conformance to § 572.36 (c). (a) Test procedure. (1) Soak the head assembly in...

  18. 49 CFR 572.192 - Head assembly.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Head assembly. 572.192 Section 572.192... Dummy, Small Adult Female § 572.192 Head assembly. (a) The head assembly consists of the head (180-1000...) of this section, the head assembly shall meet performance requirements specified in paragraph (c) of...

  19. Synchronous Firefly Algorithm for Cluster Head Selection in WSN.

    Science.gov (United States)

    Baskaran, Madhusudhanan; Sadagopan, Chitra

    2015-01-01

    Wireless Sensor Network (WSN) consists of small low-cost, low-power multifunctional nodes interconnected to efficiently aggregate and transmit data to sink. Cluster-based approaches use some nodes as Cluster Heads (CHs) and organize WSNs efficiently for aggregation of data and energy saving. A CH conveys information gathered by cluster nodes and aggregates/compresses data before transmitting it to a sink. However, this additional responsibility of the node results in a higher energy drain leading to uneven network degradation. Low Energy Adaptive Clustering Hierarchy (LEACH) offsets this by probabilistically rotating cluster heads role among nodes with energy above a set threshold. CH selection in WSN is NP-Hard as optimal data aggregation with efficient energy savings cannot be solved in polynomial time. In this work, a modified firefly heuristic, synchronous firefly algorithm, is proposed to improve the network performance. Extensive simulation shows the proposed technique to perform well compared to LEACH and energy-efficient hierarchical clustering. Simulations show the effectiveness of the proposed method in decreasing the packet loss ratio by an average of 9.63% and improving the energy efficiency of the network when compared to LEACH and EEHC.

  20. A prospective randomised study to compare the utility and outcomes of subdural and subperiosteal drains for the treatment of chronic subdural haematoma.

    LENUS (Irish Health Repository)

    Kaliaperumal, Chandrasekaran

    2012-11-01

    The usage of a drain following evacuation of a chronic subdural haematoma (CSDH) is known to reduce recurrence. In this study we aim to compare the clinical outcomes and recurrence rate of utilising two different types of drains (subperiosteal and subdural drain) following drainage of a CSDH.

  1. A COMPARATIVE STUDY IN HERNIOPLASTY WITH AND WITHOUT DRAIN AND THE ASSOCIATED COMPLICATIONS

    Directory of Open Access Journals (Sweden)

    Amruthavalli Bayya Venkatesulu

    2017-03-01

    Full Text Available BACKGROUND The present study is a comparative study to compare in Lichtenstein’s mesh repair, the need of a subcutaneous suction drain in inguinal hernias at Government General Hospital, Guntur. To study the advantages and disadvantages of using subcutaneous suction drain in Lichtenstein’s hernioplasty. MATERIALS AND METHODS In the present study, out of 50 patients,32% of patients who had undergone drainage group complained of pain and 8% of patients who had undergone non-drainage complained of pain. In our study, 0% and 4% of patients developed haematoma in drainage and non-drainage group, respectively. 12% of patients in drainage group developed seroma and 12% of patients in non-drainage group developed seroma. In the present study, 16% of cases in drainage and 20% in non-drainage group. In the present study, patients in drainage group mean postoperative hospital stay is 9.1 days and in non-drainage group is 6.7 days. The average duration of postoperative hospital stay in patients of drainage group is higher than in non-drainage group with the above results, the early postoperative complications like pain, mean postoperative stay in hospital are increased in Lichtenstein’s with drainage group. The early postoperative complications like seroma, haematoma and wound infection rates are similar in both drainage and non-drainage groups. So, it appears that suction drain usage can be restricted in Lichtenstein’s tension free mesh repair in simple inguinal hernias unless the hernia is complicated or there is extensive dissection. RESULTS The details of all the (50 cases were drawn as master chart with regard of relevance. Statistical analysis was done using Epi info version 3.5.3. P value is calculated using Chi-square test. CONCLUSION In the present study, 50 patients with inguinal hernia who had undergone Lichtenstein’s hernioplasty with subcutaneous suction drain are compared with those who had undergone Lichtenstein’s hernioplasty

  2. VT Digital Line Graph Miscellaneous Transmission Lines

    Data.gov (United States)

    Vermont Center for Geographic Information — (Link to Metadata) This datalayer is comprised of Miscellaineous Transmission Lines. Digital line graph (DLG) data are digital representations of cartographic...

  3. Association between temporomandibular disorders and abnormal head postures

    Directory of Open Access Journals (Sweden)

    Evandro Francisco FAULIN

    2015-01-01

    Full Text Available This study examines the possible correlation between the prevalence of temporomandibular disorders (TMD and different head postures in the frontal and sagittal planes using photographs of undergraduate students in the School of Dentistry at the Universidade de Brasília - UnB, Brazil. In this nonrandomized, cross-sectional study, the diagnoses of TMD were made with the Research Diagnostic Criteria (RDC/TMD axis I. The craniovertebral angle was used to evaluate forward head posture in the sagittal plane, and the interpupillary line was used to measure head tilt in the frontal plane. The measurements to evaluate head posture were made using the Software for the Assessment of Posture (SAPO. Students were divided into two study groups, based on the presence or absence of TMD. The study group comprised 46 students and the control group comprised 80 students. Data about head posture and TMD were analyzed with the Statistical Package for the Social Sciences, version 13. Most cases of TMD were classified as degenerative processes (group III, followed by disk displacement (group II and muscle disorders (group I. There was no sex predominance for the type of disorder. No association was found between prevalence rates for head postures in the frontal plane and the occurrence of TMD. The same result was found for the association of TMD diagnosis with craniovertebral angle among men and women, and the group that contained both men and women. Abnormal head postures were common among individuals both with and without TMD. No association was found between head posture evaluated in the frontal and sagittal planes and TMD diagnosis with the use of RDC/TMD.

  4. NC-Impacts of Peatland Ditching and Draining on Water Quality and Carbon Sequestration Benefits of Peatland Restoration

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Re-wetting peatlands through hydrology restoration on Pocosin Lakes National Wildlife Refuge will return previous drained wetlands to a more nature state and is...

  5. A Compositional Study Of The Phytoplankton Of Lake Drummond And The Rivers And Canals That Drain The Dismal Swamp

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — A six-week study of the phytoplankton in Lake Drummond and the canals and river which drain the Dismal Swamp resulted in the identification of 110 species. These...

  6. Bilateral abducens nerve and right facial nerve palsy occuring after head trauma

    Directory of Open Access Journals (Sweden)

    ismail Boyraz

    2016-06-01

    Full Text Available Lesions of the nervus abducens, the 6th cranial nerve tend to be rare, usually occur suddenly following head injuries. A 43-year-old male patient presented with a history of fall from a height due to an occupational accident on the date of 11.01.2014. Cranial tomography demonstrated bilateral epidural hematoma. The epidural hematoma was drained during the operation. After the surgery, eye examination showed no vision loss, except limited bilateral lateral gaze. When the patient was unable to walk due to diplopia, he was advised to close one eye. On the right side, there were findings suggesting central facial paralysis. There may be multiple cranial nerve damage following head injury. Therefore, all cranial nerves should be thoroughly examined. [J Contemp Med 2016; 6(2.000: 110-113

  7. Impact of a drain field plate on the breakdown characteristics of AlInN/GaN MOSHEMT

    Science.gov (United States)

    Jena, Kanjalochan; Swain, Raghunandan; Lenka, T. R.

    2015-11-01

    In this paper, a novel AlInN/GaN metal oxide semiconductor high electron mobility transistor (MOSHEMT) employing the drain field plate technique is proposed and the effect of a drain field plate on the breakdown voltage (BV) is investigated. A reduction of the peak electric field is required to achieve AlInN/GaN MOSHEMTs with a high BV. The proposed AlInN/GaN MOSHEMT with both gate and drain field plates simultaneously reduces the electric field concentration at the gate and the drain edge by decreasing the potential gradient along the channel for the 2 dimensional electron gas (2DEG). The reduction in the peak electric field at the drain edge of the proposed device leads to a 57% increase in BV compared with the BV for an AlInN/GaN MOSHEMT with a gate field plate only. A significantly higher BV can be achieved by optimizing the gate-to-drain distance (L gd ), the length of the drain field plate (L dfp ) and the thickness of the SiN passivation layer thickness (T SiN ). A detailed breakdown analysis of the device was carried out using Silvaco Technology Computer Aided Design (TCAD). The detailed numerical simulations were done by using the non-local energy balance (EB) transport model, which was calibrated with the previously published experimental results. The results showed a great potential for applications of the drain-field-plated AlInN/GaN MOSHEMT to deliver high currents and high powers in microwave technologies.

  8. Influence of slow-release urea on nitrogen balance and portal-drained visceral nutrient flux in beef steers

    DEFF Research Database (Denmark)

    Taylor-Edwards, C C; Elam, N A; Kitts, S E

    2009-01-01

    Two experiments were conducted to evaluate the effects of slow-release urea (SRU) versus feed-grade urea on portal-drained visceral (PDV) nutrient flux, nutrient digestibility, and total N balance in beef steers.......Two experiments were conducted to evaluate the effects of slow-release urea (SRU) versus feed-grade urea on portal-drained visceral (PDV) nutrient flux, nutrient digestibility, and total N balance in beef steers....

  9. Landslides at Beachy Head, Sussex

    OpenAIRE

    Pennington, Catherine

    2007-01-01

    Beachy Head (Figures 1 and 2) is a famous natural and historic site and tourist attraction on the south coast. The cliff top area is part of the Downland Country Park managed by Eastbourne District Council. The section of cliff surveyed at Beachy Head is situated to the east of the modern lighthouse. The survey spans a 400 m south-facing stretch of beach with a cliff height of between 120 and 160 m. Cliffs and lighthouse at Beachy Head As part of a programme of work monitoring coast...

  10. Return of the talking heads

    DEFF Research Database (Denmark)

    Reinecke Hansen, Kenneth; Bro, Peter; Andersson, Ralf

    2016-01-01

    . In order to analyze the latest development entering the third wave, we propose a theoretically based dramaturgical model for the television news item. The analysis concludes that, with the current ‘return’ of the talking heads format, the pre-produced and pre-packaged bulletin program about past events......The present article suggests that the brief history of Western television news dramaturgy can be expounded as three major waves: from the early days of the talking heads in the studio, over the narrativization of the field report to a (re-)current studio- and field-based talking heads format...

  11. Predictive Compensator Optimization for Head Tracking Lag in Virtual Environments

    Science.gov (United States)

    Adelstein, Barnard D.; Jung, Jae Y.; Ellis, Stephen R.

    2001-01-01

    We examined the perceptual impact of plant noise parameterization for Kalman Filter predictive compensation of time delays intrinsic to head tracked virtual environments (VEs). Subjects were tested in their ability to discriminate between the VE system's minimum latency and conditions in which artificially added latency was then predictively compensated back to the system minimum. Two head tracking predictors were parameterized off-line according to cost functions that minimized prediction errors in (1) rotation, and (2) rotation projected into translational displacement with emphasis on higher frequency human operator noise. These predictors were compared with a parameterization obtained from the VE literature for cost function (1). Results from 12 subjects showed that both parameterization type and amount of compensated latency affected discrimination. Analysis of the head motion used in the parameterizations and the subsequent discriminability results suggest that higher frequency predictor artifacts are contributory cues for discriminating the presence of predictive compensation.

  12. Changes in neck muscle electromyography and forward head posture of children when carrying schoolbags.

    Science.gov (United States)

    Kim, M H; Yi, C H; Kwon, O Y; Cho, S H; Yoo, W G

    2008-06-01

    This study tested the effects of three alternative types of backpack on head posture and neck muscle electromyography (EMG) in children. Four loading conditions were tested: no pack; a backpack; a double pack; a modified double pack (designed with a backpack and a front pack weighing 10% and 5% of body weight, respectively). Dependent variables were neck muscle activity, forward head angle and forward head distance (the perpendicular distance from C7 to a vertical line through the tragus of the ear). Fifteen children were asked to walk at a speed of 0.8 m/s on a treadmill. The EMG activity of upper trapezius, sternocleidomastoid and midcervical paraspinals muscles and the forward head angle and forward head distance were all significantly higher when carrying a backpack than for the other conditions. When carrying a double pack, there was a backward head posture characterised by an increased negative forward head angle, decreased forward head distance, increased sternocleidomastoid EMG signal and decreased midcervical paraspinals EMG signal, compared to carrying no pack. When carrying a modified double pack, the forward head angle and forward head distance decreased when compared to carrying a backpack. These findings indicate that the modified double pack minimises postural deviation.

  13. QTL mapping of leafy heads by genome resequencing in the RIL population of Brassica rapa.

    Directory of Open Access Journals (Sweden)

    Xiang Yu

    Full Text Available Leaf heads of cabbage (Brassica oleracea, Chinese cabbage (B. rapa, and lettuce (Lactuca sativa are important vegetables that supply mineral nutrients, crude fiber and vitamins in the human diet. Head size, head shape, head weight, and heading time contribute to yield and quality. In an attempt to investigate genetic basis of leafy head in Chinese cabbage (B. rapa, we took advantage of recent technical advances of genome resequencing to perform quantitative trait locus (QTL mapping using 150 recombinant inbred lines (RILs derived from the cross between heading and non-heading Chinese cabbage. The resequenced genomes of the parents uncovered more than 1 million SNPs. Genotyping of RILs using the high-quality SNPs assisted by Hidden Markov Model (HMM generated a recombination map. The raw genetic map revealed some physical assembly error and missing fragments in the reference genome that reduced the quality of SNP genotyping. By deletion of the genetic markers in which recombination rates higher than 20%, we have obtained a high-quality genetic map with 2209 markers and detected 18 QTLs for 6 head traits, from which 3 candidate genes were selected. These QTLs provide the foundation for study of genetic basis of leafy heads and the other complex traits.

  14. Counting heads in Cairo.

    Science.gov (United States)

    1994-09-14

    Representatives of 182 nations gathered in Cairo in September, 1994, at the Un Conference on Population and Development. The resulting 113-page Draft Program of Action contains sober discussions on demographic issues, including projections of population increase in the decades ahead. It focuses on the potential growth of famine, disease, warfare, environmental degradation, and general human misery if the world's population cannot be stabilized at around 8 billion in the next 20 years. The 1994 figure stands at about 5.7 billion, and there will be 12.5 billion people if no action is taken. Previous conferences hosted under the UN helped spark a remarkable decline in fertility rates, especially in Indonesia and Thailand. Even in populous Bangladesh, some 40% of women now use contraceptives, while the fertility rate has dropped from 7 to 4.2 in 2 decades. The proposals debated in Cairo include sustainable development, gender equality, and the empowerment of women. Whatever the country or culture, fertility rates tend to fall dramatically as women become more educated. This has been borne out almost everywhere, most notably in Japan and Singapore. The conference has been criticized by the Vatican as advocating an international standard for easy abortion, encouraging sex education for teenagers, and sanctioning marriages other than between a man and a woman. Some conservative Muslim thinkers have also complained that it promotes Western values and fosters illicit sex. Many supporters of population planning have argued that the empowerment of women will reduce the incidence of abortion. The Cairo document will alienate many across Asia with its references to the plurality of family forms, including the large number of households headed by single parents. The one goal on which everyone can agree is the need to promote policies that will stabilize the global headcount.

  15. Gate Last Indium-Gallium-Arsenide MOSFETs with Regrown Source-Drain Regions and ALD Dielectrics

    Science.gov (United States)

    Carter, Andrew Daniel

    III-V-based MOSFETs have the potential to exceed the performance of silicon-based MOSFETs due to the semiconductor's small electron effective mass. Modern silicon-based MOSFETs with 22 nm gate lengths utilize high-k gate insulators and non-planar device geometries to optimize device performance. III-V HEMT technology has achieved similar gate lengths, but large source-drain access resistances and the lack of high-quality gate insulators prevent further device performance scaling. Sub-22 nm gate length III-V MOSFETs require metal-semiconductor contact resistivity to be less than 1 ohm-micron squared, gate insulators with less than 1 nm effective oxide thickness, and semiconductor-insulator interface trap densities less than 2E12 per square centimeter per electron volt. This dissertation presents InGaAs-based III-V MOSFET process flows and device results to assess their use in VLSI circuits. Previous III-V MOSFET results focused on long (>100 nm) gate lengths and ion implantation for source-drain region formation. Scaling III-V MOSFETs to shorter gate lengths requires source-drain regions that have low sheet resistance, high mobile charge densities, and low metal-semiconductor contact resistance. MBE- and MOCVD-based raised epitaxial source-drain regrowth meet these requirements. MBE InAs source-drain regrowth samples have shown 0.5 to 2 ohm-micron squared metal semiconductor contact resistivities. MOCVD InGaAs source-drain regrowth samples have shown resistance to InGaAs MOSFETs. Gate insulators on III-V materials require large conduction band offsets to the channel, high dielectric permittivities, and low semiconductor-insulator interface trap densities. An in-situ hydrogen plasma / trimethylaluminum treatment has been developed to lower the gate semiconductor-insulator interface trap density. This treatment, done immediately before gate insulator deposition, has been shown to lower MOS capacitor interface trap densities by more than a factor of two. Devices using

  16. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... digital cloud server. Currently, MRI is the most sensitive imaging test of the head (particularly the brain) ... Society of Urogenital Radiology note that the available data suggest that it is safe to continue breastfeeding ...

  17. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... medically necessary. MRI may not always distinguish between cancer tissue and fluid, known as edema . MRI typically ... Brain Tumors Radiation Therapy for Head and Neck Cancer Others : American Stroke Association National Stroke Association top ...

  18. Magnetic Resonance Imaging (MRI) -- Head

    Medline Plus

    Full Text Available ... a computer to produce detailed pictures of the brain and other cranial structures that are clearer and ... sensitive imaging test of the head (particularly the brain) in routine clinical practice. top of page What ...

  19. Magnetic Resonance Imaging (MRI) -- Head

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    Full Text Available ... of the head (particularly the brain) in routine clinical practice. top of page What are some common ... acutely injured; however, this decision is based on clinical judgment. This is because traction devices and many ...

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    Full Text Available ... MRI scanners are air-conditioned and well-lit. Music may be played through the headphones to help ... page Additional Information and Resources RTAnswers.org : Radiation Therapy for Brain Tumors Radiation Therapy for Head and ...