Hazardous substances releases associated with Hurricanes Katrina and Rita in industrial settings, Louisiana and Texas.

Science.gov (United States)

Ruckart, Perri Zeitz; Orr, Maureen F; Lanier, Kenneth; Koehler, Allison

2008-11-15

The scientific literature concerning the public health response to the unprecedented hurricanes striking the Gulf Coast in August and September 2005 has focused mainly on assessing health-related needs and surveillance of injuries, infectious diseases, and other illnesses. However, the hurricanes also resulted in unintended hazardous substances releases in the affected states. Data from two states (Louisiana and Texas) participating in the Hazardous Substances Emergency Events Surveillance (HSEES) system were analyzed to describe the characteristics of hazardous substances releases in industrial settings associated with Hurricanes Katrina and Rita. HSEES is an active multi-state Web-based surveillance system maintained by the Agency for Toxic Substances and Disease Registry (ATSDR). In 2005, 166 hurricane-related hazardous substances events in industrial settings in Louisiana and Texas were reported. Most (72.3%) releases were due to emergency shut downs in preparation for the hurricanes and start-ups after the hurricanes. Emphasis is given to the contributing causal factors, hazardous substances released, and event scenarios. Recommendations are made to prevent or minimize acute releases of hazardous substances during future hurricanes, including installing backup power generation, securing equipment and piping to withstand high winds, establishing procedures to shutdown process operations safely, following established and up-to-date start-up procedures and checklists, and carefully performing pre-start-up safety reviews.

Hazardous substances releases associated with Hurricanes Katrina and Rita in industrial settings, Louisiana and Texas

International Nuclear Information System (INIS)

Ruckart, Perri Zeitz; Orr, Maureen F.; Lanier, Kenneth; Koehler, Allison

2008-01-01

The scientific literature concerning the public health response to the unprecedented hurricanes striking the Gulf Coast in August and September 2005 has focused mainly on assessing health-related needs and surveillance of injuries, infectious diseases, and other illnesses. However, the hurricanes also resulted in unintended hazardous substances releases in the affected states. Data from two states (Louisiana and Texas) participating in the Hazardous Substances Emergency Events Surveillance (HSEES) system were analyzed to describe the characteristics of hazardous substances releases in industrial settings associated with Hurricanes Katrina and Rita. HSEES is an active multi-state Web-based surveillance system maintained by the Agency for Toxic Substances and Disease Registry (ATSDR). In 2005, 166 hurricane-related hazardous substances events in industrial settings in Louisiana and Texas were reported. Most (72.3%) releases were due to emergency shut downs in preparation for the hurricanes and start-ups after the hurricanes. Emphasis is given to the contributing causal factors, hazardous substances released, and event scenarios. Recommendations are made to prevent or minimize acute releases of hazardous substances during future hurricanes, including installing backup power generation, securing equipment and piping to withstand high winds, establishing procedures to shutdown process operations safely, following established and up-to-date start-up procedures and checklists, and carefully performing pre-start-up safety reviews

Hazardous substances releases associated with Hurricanes Katrina and Rita in industrial settings, Louisiana and Texas

Energy Technology Data Exchange (ETDEWEB)

Ruckart, Perri Zeitz [Division of Health Studies, Agency for Toxic Substances and Disease Registry, Atlanta, GA (United States)], E-mail: afp4@cdc.gov; Orr, Maureen F. [Division of Health Studies, Agency for Toxic Substances and Disease Registry, Atlanta, GA (United States); Lanier, Kenneth; Koehler, Allison [Louisiana Department of Health and Hospitals, Office of Public Health, New Orleans, LA (United States)

2008-11-15

The scientific literature concerning the public health response to the unprecedented hurricanes striking the Gulf Coast in August and September 2005 has focused mainly on assessing health-related needs and surveillance of injuries, infectious diseases, and other illnesses. However, the hurricanes also resulted in unintended hazardous substances releases in the affected states. Data from two states (Louisiana and Texas) participating in the Hazardous Substances Emergency Events Surveillance (HSEES) system were analyzed to describe the characteristics of hazardous substances releases in industrial settings associated with Hurricanes Katrina and Rita. HSEES is an active multi-state Web-based surveillance system maintained by the Agency for Toxic Substances and Disease Registry (ATSDR). In 2005, 166 hurricane-related hazardous substances events in industrial settings in Louisiana and Texas were reported. Most (72.3%) releases were due to emergency shut downs in preparation for the hurricanes and start-ups after the hurricanes. Emphasis is given to the contributing causal factors, hazardous substances released, and event scenarios. Recommendations are made to prevent or minimize acute releases of hazardous substances during future hurricanes, including installing backup power generation, securing equipment and piping to withstand high winds, establishing procedures to shutdown process operations safely, following established and up-to-date start-up procedures and checklists, and carefully performing pre-start-up safety reviews.

Surveillance of hazardous substances releases due to system interruptions, 2002.

Science.gov (United States)

Orr, Maureen F; Ruckart, Perri Zeitz

2007-04-11

The Hazardous Substances Emergency Events Surveillance (HSEES) system collected information on 9014 acute hazardous substance releases in 15 participating states in 2002. There were 3749 fixed-facility manufacturing events, of which 2100 involved "interruptions" to normal processing and 1649 "comparisons" that did not involve interruption. Equipment failure (69%) or intentional acts (20%) were the main root factor. Many events occurred in October and November in three states (Texas, Louisiana, and New Jersey), in three manufacturing industries (industrial and miscellaneous chemicals; petroleum refining; and plastics, synthetics, and resins). In interruption events, the substance categories most often released were mixtures, other inorganic substances, and volatile organic compounds and those most often causing injury were acids, chlorine, bases, and ammonia. Comparison events resulted in more acutely injured persons (408 versus 59) and more evacuees (11,318 versus 335) than interruption events and therefore may receive more public health attention. Because of the large number of interruption events, targeted prevention activities, including management of change procedures, lessons-learned implementation, process hazards analysis, and appropriate protection for workers could be economically advantageous and improve environmental quality. Efforts should focus on the identified areas of greater occurrence. The relationship of weather and equipment failure with interruption events needs further investigation.

41 CFR 102-75.340 - Where hazardous substance activity has been identified on property proposed for disposal, what...

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Where hazardous... Provisions Relating to Hazardous Substance Activity § 102-75.340 Where hazardous substance activity has been... offer to purchase and the conveyance document? Where the existence of hazardous substance activity has...

78 FR 69360 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2013-11-19

...] National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List: Partial... and Hazardous Substances Pollution Contingency Plan (NCP). The EPA and the State of California... Corp Air Station Superfund Site without prior Notice of Intent for Partial Deletion because EPA views...

75 FR 43115 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2010-07-23

... and Hazardous Substances Pollution Contingency Plan; National Priorities List: Intent to Partially..., as amended, is an appendix of the National Oil and Hazardous Substances Pollution Contingency Plan... Intent for Partial Deletion because EPA views this as a noncontroversial revision and anticipates no...

76 FR 45484 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2011-07-29

... and Hazardous Substances Pollution Contingency Plan; National Priorities List: Notice of Intent for..., as amended, is an appendix of the National Oil and Hazardous Substances Pollution Contingency Plan... PBL Superfund Site without prior Notice of Intent for Deletion because EPA views this as a...

76 FR 18136 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2011-04-01

... and Hazardous Substances Pollution Contingency Plan; National Priorities List: Deletion of the Norwood... amended, is an appendix of the National Oil and Hazardous Substances Pollution Contingency Plan (NCP). The... we view this as a noncontroversial revision and anticipate no adverse comment. We have explained our...

76 FR 81904 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2011-12-29

... and Hazardous Substances Pollution Contingency Plan; National Priorities List: Deletion of the Hipps..., as amended, is an appendix of the National Oil and Hazardous Substances Pollution Contingency Plan... of Intent to Delete because we view this as a noncontroversial revision and anticipate no adverse...

77 FR 67783 - National Oil and Hazardous Substance Pollution Contingency Plan National Priorities List...

Science.gov (United States)

2012-11-14

... and Hazardous Substance Pollution Contingency Plan National Priorities List: Deletion of the Waste... and Hazardous Substances Pollution Contingency Plan (NCP). EPA and the State of Michigan, through the...-Holland Lagoons Superfund Site without prior Notice of Intent to Delete because we view this as a...

Chemical incidents resulted in hazardous substances releases in the context of human health hazards.

OpenAIRE

Palaszewska-Tkacz, Anna; Czerczak, Sławomir; Konieczko, Katarzyna

2017-01-01

Objectives: The research purpose was to analyze data concerning chemical incidents in Poland collected in 1999–2009 in terms of health hazards. Material and Methods: The data was obtained, using multimodal information technology (IT) system, from chemical incidents reports prepared by rescuers at the scene. The final analysis covered sudden events associated with uncontrolled release of hazardous chemical substances or mixtures, which may potentially lead to human exposure. Releases of uniden...

Sustainable hazardous substances management in the supply chain

NARCIS (Netherlands)

Veenvliet, H.; Valk, van der W.; Weele, van A.J.; Esposito, E.

2012-01-01

Being compliant to legal hazardous substances regulations is difficult for multinational companies that have a global network of suppliers. The presence of these chemicals has to be monitored throughout the supply chain often even up until the raw materials suppliers. Companies have also to deal

75 FR 33747 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2010-06-15

... and Hazardous Substances Pollution Contingency Plan; National Priorities List: Notice of Intent for... Notice of Intent to Delete the soils of Operable Unit 1 and the underlying ground water of the... National Oil and Hazardous Substances Pollution Contingency Plan (NCP). The EPA and the State of Texas...

78 FR 60721 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2013-10-02

...] National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List: Deletion of the... final Notice of Deletion of the Ludlow Sand & Gravel Superfund Site (Site), located in the Town of Paris..., as amended, is an appendix of the National Oil and Hazardous Substances Pollution Contingency Plan...

Hazardous substances in wastewater systems:a delicate issue for wastewater management

OpenAIRE

Palmquist, Helena

2001-01-01

Many substances derived from human activity end up in wastewater systems at some point. A large number of different substances - up to 30,000 - are present in wastewater. Some of them are valuable, such as nitrogen and phosphorus, but there are also hazardous substances such as heavy metals and anthropogenic organic substances. To be able to utilise the wastewater nutrients on arable land (agriculture, forestry or other alternatives), it is of great importance to investigate the sources of ha...

78 FR 48844 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2013-08-12

... and Hazardous Substances Pollution Contingency Plan; National Priorities List: Deletion of the Mosley... National Oil and Hazardous Substances Pollution Contingency Plan (NCP). The EPA and the State of Oklahoma... Deletion of the MRSL Superfund Site without prior Notice of Intent to Delete because we view this as a...

EMERGENCY RESPONSE PROCEDURES FOR CONTROL OF HAZARDOUS SUBSTANCE RELEASES

Science.gov (United States)

Information is provided for selecting the best spill stabilization controls for hazardous substances regulated by the Comprehensive Enviromental Response, Compensation and Liability Act of 1980 (CERCLA). Information is also provided on the onsite assessment of spill severity, app...

78 FR 16612 - National Oil and Hazardous Substances Pollution Contingency Plan; Revision To Increase Public...

Science.gov (United States)

2013-03-18

... Hazardous Substances Pollution Contingency Plan (NCP) to broaden the technology, to include computer... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 300 [EPA-HQ-SFUND-2012-0738; FRL-9791-4] National Oil and Hazardous Substances Pollution Contingency Plan; Revision To Increase Public Availability of the...

75 FR 54821 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List; Intent...

Science.gov (United States)

2010-09-09

... and Hazardous Substance Pollution Contingency Plan; National Priorities List; Intent for Partial... amended, is an Appendix of the National Oil and Hazardous Substances Pollution Contingency Plan (NCP). The... Superfund Site without prior Notice of Intent for Partial Deletion because EPA views this as a...

76 FR 70105 - National Oil and Hazardous Substance Pollution Contingency Plan National Priorities List: Partial...

Science.gov (United States)

2011-11-10

... and Hazardous Substance Pollution Contingency Plan National Priorities List: Partial Deletion of the... appendix of the National Oil and Hazardous Substances Pollution Contingency Plan (NCP). EPA and the State... property PINs listed above. The deletion of these two parcels from the Site affects all surface soils...

75 FR 47521 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List: Intent...

Science.gov (United States)

2010-08-06

... and Hazardous Substance Pollution Contingency Plan; National Priorities List: Intent To Delete the... appendix of the National Oil and Hazardous Substances Pollution Contingency Plan (NCP). The EPA and the... Corporation (Markhams) Superfund Site without prior notice of intent to delete because we view this as a...

Fate and monitoring of hazardous substances in temporary rivers

NARCIS (Netherlands)

Ademollo, N.; Capri, S.; Froebrich, J.; Patrolecco, L.; Polesello, S.; Puddu, A.; Rusconi, M.; Valsecchi, S.

2011-01-01

Under climate-change conditions, temporary rivers will be the dominant surface-water bodies of the Mediterranean region. In order to manage this kind of water body appropriately, it is necessary to understand the chemical and ecological processes that involve hazardous substances in these

Hazardous substances shipping at inland water harbors

International Nuclear Information System (INIS)

Benkovic, Z.

2009-01-01

Safety measures and regulations system covering the aspects of fire protection, professional and ecological safety are aimed to create a safe working environment, by detection and remedy of conditions that are potentially hazardous for the well-being of the employees or are leading to certain undesired events. Such unwanted incidents may result in different consequences: operating person's injury, environment pollution or material damage. This study attempts to illustrate the organization of work during hazardous matter loading and unloading at inland water harbors, based on legal provisions and decrees involving safety precautions, and in order to achieve constant enhancement of operating procedure, decreasing thereby the number of work-related injuries and various accidental situations. Fundamental precondition required to prevent possible accidents and to optimize general safety policy is to recognize and control any danger or potential hazard, as well as to be familiar with the legal provisions covering the inland waterway transport of harmful substances.(author)

41 CFR 102-75.130 - If hazardous substance activity took place on the property, what specific information must an...

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false If hazardous substance... Utilization of Excess Real Property Title Report § 102-75.130 If hazardous substance activity took place on... quantity of such hazardous substance and the time at which such storage, release, or disposal took place...

Small WEEE: determining recyclables and hazardous substances in plastics.

Science.gov (United States)

Dimitrakakis, Emmanouil; Janz, Alexander; Bilitewski, Bernd; Gidarakos, Evangelos

2009-01-30

An examination regarding the determination of recyclables and hazardous substances in small waste electrical and electronic equipment (WEEE) found in the residual household waste stream of the city of Dresden, Germany, is described. Firstly, attitudes towards the disposal of small WEEE in the latter are assessed, and product types and categories which mostly contribute to its composition are identified. Physical parameters which could be used as mechanical sorting criteria are measured, and the material composition of the small WEEE found is determined. The hazardous substances' "base" charge in the residual waste is established by means of atomic absorption spectrometry and ionic chromatography, as a first step in estimating the contribution of small WEEE to its pollutant load. Consequently, the content of small WEEE plastics in key heavy metals and halogens is determined. Key conclusions are drawn concerning the future strategic development and practical implementation of the 2002/96/EC Directive, in relation to small WEEE management and recycling.

Small WEEE: Determining recyclables and hazardous substances in plastics

International Nuclear Information System (INIS)

Dimitrakakis, Emmanouil; Janz, Alexander; Bilitewski, Bernd; Gidarakos, Evangelos

2009-01-01

An examination regarding the determination of recyclables and hazardous substances in small waste electrical and electronic equipment (WEEE) found in the residual household waste stream of the city of Dresden, Germany, is described. Firstly, attitudes towards the disposal of small WEEE in the latter are assessed, and product types and categories which mostly contribute to its composition are identified. Physical parameters which could be used as mechanical sorting criteria are measured, and the material composition of the small WEEE found is determined. The hazardous substances' 'base' charge in the residual waste is established by means of atomic absorption spectrometry and ionic chromatography, as a first step in estimating the contribution of small WEEE to its pollutant load. Consequently, the content of small WEEE plastics in key heavy metals and halogens is determined. Key conclusions are drawn concerning the future strategic development and practical implementation of the 2002/96/EC Directive, in relation to small WEEE management and recycling

Determination of hazardous substances in food basket eggs in Tehran, Iran: A preliminary study

OpenAIRE

Salar-Amoli, Jamileh; Ali-Esfahani, Tahereh

2015-01-01

Extensive distribution of hazardous substances in food chain and the deleterious effect of their residues on public health are a great concern of the society. Chicken eggs, as one of the most popular food commodities, in different parts of Tehran (Iran) were analyzed for two groups of hazardous substances including some organochlorine pesticides (OC) such as aldrin, lindane, dieldrin, dichlorodiphenyltrichloroethane, heptachlor and endusulfan) and heavy metals namely mercury (Hg), arsenic (As...

Agency for Toxic Substances and Disease Registry (ATSDR) Hazardous Waste Site Polygon Data, 1996

Data.gov (United States)

National Aeronautics and Space Administration — The Agency for Toxic Substances and Disease Registry (ATSDR) Hazardous Waste Site Polygon Data, 1996 consists of 2042 polygons for selected hazardous waste sites...

Optimal routing of hazardous substances in time-varying, stochastic transportation networks

International Nuclear Information System (INIS)

Woods, A.L.; Miller-Hooks, E.; Mahmassani, H.S.

1998-07-01

This report is concerned with the selection of routes in a network along which to transport hazardous substances, taking into consideration several key factors pertaining to the cost of transport and the risk of population exposure in the event of an accident. Furthermore, the fact that travel time and the risk measures are not constant over time is explicitly recognized in the routing decisions. Existing approaches typically assume static conditions, possibly resulting in inefficient route selection and unnecessary risk exposure. The report described the application of recent advances in network analysis methodologies to the problem of routing hazardous substances. Several specific problem formulations are presented, reflecting different degrees of risk aversion on the part of the decision-maker, as well as different possible operational scenarios. All procedures explicitly consider travel times and travel costs (including risk measures) to be stochastic time-varying quantities. The procedures include both exact algorithms, which may require extensive computational effort in some situations, as well as more efficient heuristics that may not guarantee a Pareto-optimal solution. All procedures are systematically illustrated for an example application using the Texas highway network, for both normal and incident condition scenarios. The application illustrates the trade-offs between the information obtained in the solution and computational efficiency, and highlights the benefits of incorporating these procedures in a decision-support system for hazardous substance shipment routing decisions

Analysis on the Industrial Design of Food Package and the Component of Hazardous Substance in the Packaging Material

OpenAIRE

Wei-Wen Huang

2015-01-01

Transferring the hazardous chemicals contained in food packaging materials into food would threaten the health of consumers, therefore, the related laws and regulations and the detection method of hazardous substance have been established at home and abroad to ensure the safety to use the food packaging material. According to the analysis on the hazardous component in the food packaging, a set of detection methods for hazardous substance in the food packaging was established in the paper and ...

78 FR 73449 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2013-12-06

... Substances Pollution Contingency Plan (NCP). This partial deletion pertains to the soil of 1,154 residential...] National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List: Partial Deletion of the Omaha Lead Superfund Site AGENCY: Environmental Protection Agency (EPA). ACTION: Final rule...

78 FR 11620 - National Oil and Hazardous Substances Pollution Contingency Plan National Priorities List...

Science.gov (United States)

2013-02-19

... and Hazardous Substances Pollution Contingency Plan National Priorities List: Deletion of the Kerr... Substances Pollution Contingency Plan (NCP). EPA and the State of Illinois, through the Illinois... because we view this as a noncontroversial revision and anticipate no adverse comment. We have explained...

76 FR 20605 - National Oil and Hazardous Substance Pollution Contingency Plan National Priorities List...

Science.gov (United States)

2011-04-13

... and Hazardous Substance Pollution Contingency Plan National Priorities List: Deletion of the... Substances Pollution Contingency Plan (NCP). EPA and the State of Michigan, through the Michigan Department... Delete because we view this as a noncontroversial revision and anticipate no adverse comment. We have...

78 FR 45905 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2013-07-30

... and Hazardous Substances Pollution Contingency Plan; National Priorities List: Deletion of the Craig... Substances Pollution Contingency Plan (NCP). The EPA and the Commonwealth of Pennsylvania, through the... Craig Farm Drum Superfund Site without prior Notice of Intent to Delete because we view this as a...

76 FR 32115 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2011-06-03

... and Hazardous Substances Pollution Contingency Plan; National Priorities List: Intent To Delete the... Substances Pollution Contingency Plan (NCP). The EPA and the State of Delaware, through the Delaware... Delete because EPA views this as a noncontroversial revision and anticipates no adverse comment. We have...

78 FR 45167 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2013-07-26

... and Hazardous Substances Pollution Contingency Plan; National Priorities List: Deletion of the Cannon... Substances Pollution Contingency Plan (NCP). The EPA and the State of Massachusetts, through the...), Superfund Site without prior Notice of Intent to Delete because we view this as a noncontroversial revision...

Reporting continuous releases of hazardous and extremely hazardous substances under CERCLA and EPCRA

International Nuclear Information System (INIS)

1995-01-01

This guidance is designed to provide basic instruction to US DOE and DOE operations contractor personnel on how to characterize CERCLA and EPCRA hazardous substance releases as continuous and how to prepare and deliver continuousreleasee reports to Federal, State, and local authorities. DOE staff should use this guidance as an overview of the continuous release requirements, a quick ready reference guide for specific topics concerning continuous releases and a step-by-step guide for the process of identifying and reporting continuous releases

76 FR 50441 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2011-08-15

... and Hazardous Substance Pollution Contingency Plan; National Priorities List: Deletion of the... Substances Pollution Contingency Plan (NCP). The EPA and the State of New Jersey, through the New Jersey... Deletion of the Sayreville Landfill Superfund Site without prior Notice of Intent to Delete because we view...

78 FR 66325 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2013-11-05

...] National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List: Deletion of the... Substances Pollution Contingency Plan (NCP). The EPA and the State of South Carolina, through the South... because we view this as a noncontroversial revision and anticipate no adverse comment. We have explained...

EXPOSURE TO HAZARDOUS SUBSTANCES AND MALE REPRODUCTIVE HEALTH: A RESEARCH FRAMEWORK

Science.gov (United States)

The discovery in the mid-1970s that occupational exposures to pesticides could diminish or destroy the fertility of workers sparked concern about the effects of hazardous substances on male reproductive health. More recently, there is evidence that sperm quantity and quality may ...

41 CFR 102-75.135 - If no hazardous substance activity took place on the property, what specific information must an...

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false If no hazardous... DISPOSAL Utilization of Excess Real Property Title Report § 102-75.135 If no hazardous substance activity... hazardous substance activity took place, the reporting agency must include the following statement: The...

76 FR 70057 - National Oil and Hazardous Substance Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2011-11-10

... and Hazardous Substance Pollution Contingency Plan; National Priorities List: Partial Deletion of the...). Refer to Figures 1 to 3 in the deletion docket to view the location of the two parcels being proposed... Substances Pollution Contingency Plan (NCP). This direct final partial deletion is being published by EPA...

78 FR 60809 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2013-10-02

...] National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List: Deletion of the... Substances Pollution Contingency Plan (NCP). EPA and the State of New York, through the New York State... Deletion of the Site without prior Notice of Intent to Delete because EPA views this as a noncontroversial...

Risk management of hazardous substances in a circular economy.

Science.gov (United States)

Bodar, Charles; Spijker, Job; Lijzen, Johannes; Waaijers-van der Loop, Susanne; Luit, Richard; Heugens, Evelyn; Janssen, Martien; Wassenaar, Pim; Traas, Theo

2018-04-15

The ambitions for a circular economy are high and unambiguous, but day-to-day experience shows that the transition still has many difficulties to overcome. One of the current hurdles is the presence of hazardous substances in waste streams that enter or re-enter into the environment or the technosphere. The key question is: do we have the appropriate risk management tools to control any risks that might arise from the re-using and recycling of materials? We present some recent cases that illustrate current practice and complexity in the risk management of newly-formed circular economy chains. We also highlight how separate legal frameworks are still disconnected from each other in these cases, and how circular economy initiatives interlink with the European REACH regulation. Furthermore, we introduce a novel scheme describing how to decide whether a(n)(additional) risk assessment is necessary with regard to the re-use of materials containing hazardous substances. Finally, we present our initial views on new concepts for the fundamental integration of sustainability and safety aspects. These concepts should be the building blocks for the near future shifts in both policy frameworks and voluntary initiatives that support a sound circular economy transition. Copyright © 2018 Elsevier Ltd. All rights reserved.

Recommended approaches to the scientific evaluation of ecotoxicological hazards and risks of endocrine-active substances

DEFF Research Database (Denmark)

Matthiessen, Peter; Ankley, Gerald T.; Biever, Ronald C

2017-01-01

A SETAC Pellston Workshop(®) "Environmental Hazard and Risk Assessment Approaches for Endocrine-Active Substances (EHRA)" was held in February 2016 in Pensacola, Florida, USA. The primary objective of the workshop was to provide advice, based on current scientific understanding, to regulators...... and policy makers; the aim being to make considered, informed decisions on whether to select an ecotoxicological hazard- or a risk-based approach for regulating a given endocrine-disrupting substance (EDS) under review. The workshop additionally considered recent developments in the identification of EDS...... at multiple biological levels of organization for 1 or more ecologically relevant taxa. The substances selected were 17α-ethinylestradiol, perchlorate, propiconazole, 17β-trenbolone, tributyltin, and vinclozolin. The 6 case studies were not comprehensive safety evaluations but provided foundations...

Recommended approaches to the scientific evaluation of ecotoxicological hazards and risks of endocrine-active substances

Science.gov (United States)

Matthiessen, Peter; Ankley, Gerald T.; Biever, Ronald C.; Bjerregaard, Poul; Borgert, Christopher; Brugger, Kristin; Blankinship, Amy; Chambers, Janice; Coady, Katherine K.; Constantine, Lisa; Dang, Zhichao; Denslow, Nancy D.; Dreier, David; Dungey, Steve; Gray, L. Earl; Gross, Melanie; Guiney, Patrick D.; Hecker, Markus; Holbech, Henrik; Iguchi, Taisen; Kadlec, Sarah; Karouna-Renier, Natalie K.; Katsiadaki, Ioanna; Kawashima, Yukio; Kloas, Werner; Krueger, Henry; Kumar, Anu; Lagadic, Laurent; Leopold, Annegaaike; Levine, Steven L.; Maack, Gerd; Marty, Sue; Meador, James P.; Mihaich, Ellen; Odum, Jenny; Ortego, Lisa; Parrott, Joanne L.; Pickford, Daniel; Roberts, Mike; Schaefers, Christoph; Schwarz, Tamar; Solomon, Keith; Verslycke, Tim; Weltje, Lennart; Wheeler, James R.; Williams, Mike; Wolf, Jeffery C.; Yamazaki, Kunihiko

2017-01-01

A SETAC Pellston Workshop® “Environmental Hazard and Risk Assessment Approaches for Endocrine-Active Substances (EHRA)” was held in February 2016 in Pensacola, Florida, USA. The primary objective of the workshop was to provide advice, based on current scientific understanding, to regulators and policy makers; the aim being to make considered, informed decisions on whether to select an ecotoxicological hazard- or a risk-based approach for regulating a given endocrine-disrupting substance (EDS) under review. The workshop additionally considered recent developments in the identification of EDS. Case studies were undertaken on 6 endocrine-active substances (EAS—not necessarily proven EDS, but substances known to interact directly with the endocrine system) that are representative of a range of perturbations of the endocrine system and considered to be data rich in relevant information at multiple biological levels of organization for 1 or more ecologically relevant taxa. The substances selected were 17α-ethinylestradiol, perchlorate, propiconazole, 17β-trenbolone, tributyltin, and vinclozolin. The 6 case studies were not comprehensive safety evaluations but provided foundations for clarifying key issues and procedures that should be considered when assessing the ecotoxicological hazards and risks of EAS and EDS. The workshop also highlighted areas of scientific uncertainty, and made specific recommendations for research and methods-development to resolve some of the identified issues. The present paper provides broad guidance for scientists in regulatory authorities, industry, and academia on issues likely to arise during the ecotoxicological hazard and risk assessment of EAS and EDS. The primary conclusion of this paper, and of the SETAC Pellston Workshop on which it is based, is that if data on environmental exposure, effects on sensitive species and life-stages, delayed effects, and effects at low concentrations are robust, initiating environmental risk

77 FR 73289 - Hazardous Substances and Articles; Administration and Enforcement Regulations: Revisions to...

Science.gov (United States)

2012-12-10

... of Animals, and the Physicians Committee for Responsible Medicine. 1. Non-animal Testing Alternatives... Hazardous Substances Act (FHSA). DATES: This rule is effective on January 9, 2013. FOR FURTHER INFORMATION... proposed amendments to the regulations that interpret, supplement, or provide alternatives to definitions...

Detecting marine hazardous substances and organisms: sensors for pollutants, toxins, and pathogens

Directory of Open Access Journals (Sweden)

O. Zielinski

2009-09-01

Full Text Available Marine environments are influenced by a wide diversity of anthropogenic and natural substances and organisms that may have adverse effects on human health and ecosystems. Real-time measurements of pollutants, toxins, and pathogens across a range of spatial scales are required to adequately monitor these hazards, manage the consequences, and to understand the processes governing their magnitude and distribution. Significant technological advancements have been made in recent years for the detection and analysis of such marine hazards. In particular, sensors deployed on a variety of mobile and fixed-point observing platforms provide a valuable means to assess hazards. In this review, we present state-of-the-art of sensor technology for the detection of harmful substances and organisms in the ocean. Sensors are classified by their adaptability to various platforms, addressing large, intermediate, or small areal scales. Current gaps and future demands are identified with an indication of the urgent need for new sensors to detect marine hazards at all scales in autonomous real-time mode. Progress in sensor technology is expected to depend on the development of small-scale sensor technologies with a high sensitivity and specificity towards target analytes or organisms. However, deployable systems must comply with platform requirements as these interconnect the three areal scales. Future developments will include the integration of existing methods into complex and operational sensing systems for a comprehensive strategy for long-term monitoring. The combination of sensor techniques on all scales will remain crucial for the demand of large spatial and temporal coverage.

Recommended approaches to the scientific evaluation of ecotoxicological hazards and risks of endocrine-active substances.

Science.gov (United States)

Matthiessen, Peter; Ankley, Gerald T; Biever, Ronald C; Bjerregaard, Poul; Borgert, Christopher; Brugger, Kristin; Blankinship, Amy; Chambers, Janice; Coady, Katherine K; Constantine, Lisa; Dang, Zhichao; Denslow, Nancy D; Dreier, David A; Dungey, Steve; Gray, L Earl; Gross, Melanie; Guiney, Patrick D; Hecker, Markus; Holbech, Henrik; Iguchi, Taisen; Kadlec, Sarah; Karouna-Renier, Natalie K; Katsiadaki, Ioanna; Kawashima, Yukio; Kloas, Werner; Krueger, Henry; Kumar, Anu; Lagadic, Laurent; Leopold, Annegaaike; Levine, Steven L; Maack, Gerd; Marty, Sue; Meador, James; Mihaich, Ellen; Odum, Jenny; Ortego, Lisa; Parrott, Joanne; Pickford, Daniel; Roberts, Mike; Schaefers, Christoph; Schwarz, Tamar; Solomon, Keith; Verslycke, Tim; Weltje, Lennart; Wheeler, James R; Williams, Mike; Wolf, Jeffrey C; Yamazaki, Kunihiko

2017-03-01

A SETAC Pellston Workshop ® "Environmental Hazard and Risk Assessment Approaches for Endocrine-Active Substances (EHRA)" was held in February 2016 in Pensacola, Florida, USA. The primary objective of the workshop was to provide advice, based on current scientific understanding, to regulators and policy makers; the aim being to make considered, informed decisions on whether to select an ecotoxicological hazard- or a risk-based approach for regulating a given endocrine-disrupting substance (EDS) under review. The workshop additionally considered recent developments in the identification of EDS. Case studies were undertaken on 6 endocrine-active substances (EAS-not necessarily proven EDS, but substances known to interact directly with the endocrine system) that are representative of a range of perturbations of the endocrine system and considered to be data rich in relevant information at multiple biological levels of organization for 1 or more ecologically relevant taxa. The substances selected were 17α-ethinylestradiol, perchlorate, propiconazole, 17β-trenbolone, tributyltin, and vinclozolin. The 6 case studies were not comprehensive safety evaluations but provided foundations for clarifying key issues and procedures that should be considered when assessing the ecotoxicological hazards and risks of EAS and EDS. The workshop also highlighted areas of scientific uncertainty, and made specific recommendations for research and methods-development to resolve some of the identified issues. The present paper provides broad guidance for scientists in regulatory authorities, industry, and academia on issues likely to arise during the ecotoxicological hazard and risk assessment of EAS and EDS. The primary conclusion of this paper, and of the SETAC Pellston Workshop on which it is based, is that if data on environmental exposure, effects on sensitive species and life-stages, delayed effects, and effects at low concentrations are robust, initiating environmental risk

Hazardous substances in electronics: the effects of European Union risk regulation on China

NARCIS (Netherlands)

Biedenkopf, K.

2012-01-01

This article argues that European Union (EU) risk regulation of hazardous substances in electrical and electronic equipment (EEE) was both a trigger and formative factor in the development of similar Chinese regulation. The attractiveness and global interdependence of the EU market in EEE impelled a

Landfills as sinks for (hazardous) substances.

Science.gov (United States)

Scharff, Heijo

2012-12-01

The primary goal of waste regulations is to protect human health and the environment. This requires the removal from the material cycle of those materials that cannot be processed without harm. Policies to promote recycling hold a risk that pollutants are dispersed. Materials have an environmental impact during their entire life cycle from extraction through production, consumption and recycling to disposal. Essentially there are only two routes for pollutants that cannot be rendered harmless: storage in sinks or dispersion into the environment. Many sinks do not contain substances absolutely, but result in slow dispersion. Dispersion leads to exposure and impact to human health and the environment. It is therefore important to assess the impact of the release to the environment. Based on various sources this paper discusses important material flows and their potential impact. This is compared with the intentions and achievements of European environmental and resource policy. The polluter pays principle is being implemented in Europe, but lags behind implementation of waste management regulations. As long as producers are allowed to add hazardous substances to their products and don't take their products back, it is in society's best interest to carefully consider whether recycling or storage in a sink is the better solution. This requires further development of life-cycle assessment tools and harmonization of regulations. In many cases the sink is unavoidable. Landfills as sinks will be needed in the future. Fail-safe design and construction as well as sustainable management of landfills must be further developed.

Pesticides; resource recovery; hazardous substances and oil spill responses; waste disposal; biological effects

International Nuclear Information System (INIS)

Anon.

1991-01-01

In the category of pesticides this volume features close to sixty standard test method, practices, and guides for evaluating the properties and efficacy of pesticides and antimicrobial agents. Also covered are standards for hazardous substances, oil spell responses, waste disposal, and biological effects of these materials

Environmental hazard and risk characterisation of petroleum substances: a guided "walking tour" of petroleum hydrocarbons.

Science.gov (United States)

Bierkens, Johan; Geerts, Lieve

2014-05-01

Petroleum substances are used in large quantities, primarily as fuels. They are complex mixtures whose major constituents are hydrocarbons derived from crude oil by distillation and fractionation. Determining the complete molecular composition of petroleum and its refined products is not feasible with current analytical techniques because of the huge number of molecular components. This complex nature of petroleum products, with their varied number of constituents, all of them exhibiting different fate and effect characteristics, merits a dedicated hazard and risk assessment approach. From a regulatory perspective they pose a great challenge in a number of REACH processes, in particular in the context of dossier and substance evaluation but also for priority setting activities. In order to facilitate the performance of hazard and risk assessment for petroleum substances the European oil company association, CONCAWE, has developed the PETROTOX and PETRORISK spreadsheet models. Since the exact composition of many petroleum products is not known, an underlying assumption of the PETROTOX and PETRORISK tools is that the behaviour and fate of a total petroleum substance can be simulated based on the physical-chemical properties of representative structures mapped to hydrocarbon blocks (HBs) and on the relative share of each HB in the total mass of the product. To assess how differing chemical compositions affect the simulated chemical fate and toxicity of hydrocarbon mixtures, a series of model simulations were run using an artificial petroleum substance, containing 386 (PETROTOX) or 160 (PETRORISK) HBs belonging to different chemical classes and molecular weight ranges, but with equal mass assigned to each of them. To this artificial petroleum substance a guided series of subsequent modifications in mass allocation to a delineated number of HBs belonging to different chemical classes and carbon ranges was performed, in what we perceived as a guided "walking tour

75 FR 38100 - National Institute of Environmental Health Sciences Superfund Hazardous Substance Research and...

Science.gov (United States)

2010-07-01

...- traditional communication methods to make the significance and applicability of SRP-funded research... and Social Sciences Research, and National Institute of Biomedical Imaging and Bioengineering. [cir... Superfund Hazardous Substance Research and Training Program Strategic Plan; Request for Comments ACTION...

76 FR 510 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2011-01-05

..., Intergovernmental relations, Penalties, Reporting and recordkeeping requirements, Superfund, Water pollution control... and Hazardous Substances Pollution Contingency Plan; National Priorities List: Partial Deletion of the... Site is located in Albuquerque, Bernalillo County, New Mexico. After this deletion, this 62 acres will...

76 FR 11350 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2011-03-02

..., Reporting and recordkeeping requirements, Superfund, Water pollution control, Water supply. Dated: February... and Hazardous Substances Pollution Contingency Plan; National Priorities List: Partial Deletion of the... Mexico, from the National Priorities List (NPL). The NPL, promulgated pursuant to section 105 of the...

Ecotoxicological hazard and risk assessment of endocrine active substances.

Science.gov (United States)

Leopold, Annegaaike; Roberts, Mike; Matthiessen, Peter

2017-03-01

This collection of papers provides state-of-the-art science on a complex topic that has been challenging for scientists and regulators for a long time. The papers emanated from the Society of Environmental Toxicology and Chemistry (SETAC) Pellston Workshop ® Environmental Hazard and Risk Assessment Approaches for Endocrine-Active Substances (EHRA). Forty-eight international experts met in early February 2016 to discuss whether the environmental risks posed by endocrine-disrupting substances (EDS) can be reliably assessed. The primary conclusion of the workshop was that if data on environmental exposure, effects on sensitive species and life-stages, delayed effects, and effects at low concentrations are robust, initiating environmental risk assessment of EDS is scientifically sound and reliable. Integr Environ Assess Manag 2017;13:264-266. © 2016 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals, Inc. on behalf of Society of Environmental Toxicology & Chemistry (SETAC). © 2016 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals, Inc. on behalf of Society of Environmental Toxicology & Chemistry (SETAC).

77 FR 31215 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2012-05-25

... and Hazardous Substances Pollution Contingency Plan; National Priorities List: Partial Deletion of the... the surface soil, unsaturated subsurface soil, surface water and sediments of Operable Unit (OU) 1...: The Environmental Protection Agency (EPA) Region 8 announces the deletion of Operable Unit (OU) 1--the...

78 FR 47267 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2013-08-05

... and Hazardous Substances Pollution Contingency Plan; National Priorities List: Deletion of the... Contingency Plan (NCP). The EPA and the State of Oklahoma, through the Oklahoma Department of Environmental... without prior Notice of Intent to Delete because we view this as a noncontroversial revision and...

76 FR 51316 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2011-08-18

... and Hazardous Substances Pollution Contingency Plan; National Priorities List: Deletion of the... Contingency Plan (NCP). The EPA and the Commonwealth of Puerto Rico, through the Puerto Rico Environmental... Site without prior Notice of Intent to Delete because we view this as a noncontroversial revision and...

78 FR 44512 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2013-07-24

... and Hazardous Substances Pollution Contingency Plan; National Priorities List: Deletion of the Sola... Pollution Contingency Plan (NCP). The EPA and the State of California, through the Regional Water Quality...., Inc. Superfund Site without prior Notice of Intent to Delete because we view this as a...

40 CFR 355.12 - What quantities of extremely hazardous substances trigger emergency planning requirements?

Science.gov (United States)

2010-07-01

... EMERGENCY PLANNING AND NOTIFICATION Emergency Planning Who Must Comply § 355.12 What quantities of extremely... 40 Protection of Environment 27 2010-07-01 2010-07-01 false What quantities of extremely hazardous substances trigger emergency planning requirements? 355.12 Section 355.12 Protection of Environment...

75 FR 55479 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2010-09-13

... and Hazardous Substances Pollution Contingency Plan; National Priorities List: Partial Deletion of the... . SUPPLEMENTARY INFORMATION: The portion of the site to be deleted from the NPL is the surface media (soil... further actions. List of Subjects in 40 CFR Part 300 Environmental protection, Air pollution control...

76 FR 45483 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2011-07-29

... and Hazardous Substances Pollution Contingency Plan; National Priorities List: Notice of Intent for... Contingency Plan (NCP). The EPA and the State of Texas, through the Texas Commission on Environmental Quality... Notice of Deletion for SMPA Superfund Site without prior Notice of Intent for Deletion because EPA views...

77 FR 43567 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2012-07-25

... and Hazardous Substances Pollution Contingency Plan; National Priorities List: Deletion of the Fort... Contingency Plan (NCP). The EPA and the State of New Jersey, through the NJ Department of Environmental... Intent to Delete because we view this as a noncontroversial revision and anticipate no adverse comment...

Development of acute exposure guideline levels for airborne exposures to hazardous substances.

Science.gov (United States)

Krewski, Daniel; Bakshi, Kulbir; Garrett, Roger; Falke, Ernest; Rusch, George; Gaylor, David

2004-04-01

Hazardous substances can be released into the atmosphere due to industrial and transportation accidents, fires, tornadoes, earthquakes, and terrorists, thereby exposing workers and the nearby public to potential adverse health effects. Various enforceable guidelines have been set by regulatory agencies for worker and ambient air quality. However, these exposure levels generally are not applicable to rare lifetime acute exposures, which possibly could occur at high concentrations. Acute exposure guideline levels (AEGLs) provide estimates of concentrations for airborne exposures for an array of short durations that possibly could cause mild (AEGL-1), severe, irreversible, potentially disabling adverse health effects (AEGL-2), or life threatening effects (AEGL-3). These levels can be useful for emergency responders and planners in reducing or eliminating potential risks to the public. Procedures and methodologies for deriving AEGLs are reviewed in this paper that have been developed in the United States, with direct input from international representatives of OECD member-countries, by the National Advisory Committee for Acute Exposure Guidelines for Hazardous Substances and reviewed by the National Research Council. Techniques are discussed for the extrapolation of effects across different exposure durations. AEGLs provide a viable approach for assisting in the prevention, planning, and response to acute airborne exposures to toxic agents.

Differences in relationship conflict, attachment, and depression in treatment-seeking veterans with hazardous substance use, PTSD, or PTSD and hazardous substance use.

Science.gov (United States)

Owens, Gina P; Held, Philip; Blackburn, Laura; Auerbach, John S; Clark, Allison A; Herrera, Catherine J; Cook, Jerome; Stuart, Gregory L

2014-05-01

Veterans (N = 133) who were seeking treatment in either the Posttraumatic Stress Program or Substance Use Disorders Program at a Veterans Affairs Medical Center (VAMC) and, based on self-report of symptoms, met clinical norms for posttraumatic stress disorder (PTSD) or hazardous substance use (HSU) completed a survey related to relationship conflict behaviors, attachment styles, and depression severity. Participants were grouped into one of three categories on the basis of clinical norm criteria: PTSD only, HSU only, and PTSD + HSU. Participants completed the PTSD Checklist-Military, Experiences in Close Relationships Scale-Short Form, Center for Epidemiologic Studies-Depression scale, Alcohol Use Disorders Identification Test, Drug Use Disorders Identification Test, and Psychological Aggression and Physical Violence subscales of the Conflict Tactics Scale. Most participants were male and Caucasian. Significant differences were found between groups on depression, avoidant attachment, psychological aggression perpetration and victimization, and physical violence perpetration and victimization. Post hoc analyses revealed that the PTSD + HSU group had significantly higher levels of depression, avoidant attachment, and psychological aggression than the HSU only group. The PTSD + HSU group had significantly higher levels of physical violence than did the PTSD only group, but both groups had similar mean scores on all other variables. Potential treatment implications are discussed.

utilization of adsorption and/or liquid membranes techniques in treatment of some hazardous substances

International Nuclear Information System (INIS)

Hussin, L.M.S.

2011-01-01

environmental pollution, as a consequence of the industrialization process, is one of the major problems that has to be solved and controlled. The most important treatment processes for metals and dyes contaminated waste streams include chemical precipitation, membrane, filtration, ion exchange, carbon adsorption and coprecipitation/adsorption. However, all these techniques have their inherent advantages and limitations in applications. These processes usually need expensive facility and high maintenance cost. Therefore, there is a need for more economical alternative technologies for the treatment of metals and dyes contaminated waste streams. The aim of present work is to study the treatment of some hazardous substances such as heavy metals e.g. ( lead, cobalt and strontium) and dyes e.g. ( acid red 73, and acid blue 74 ) using either adsorption or liquid emulsion membrane techniques. The experimental part deals with the application of adsorption and liquid emulsion membrane techniques for removal of some hazardous substances such as metal ions ( lead, cobalt and strontium) and dyes (acid red 73 and acid blue 74). All the apparatus and techniques employed were described.

Recommended approaches to the scientific evaluation of ecotoxicological hazards and risks of endocrine‐active substances

Science.gov (United States)

A SETAC Pellston Workshop™ ?‘Environmental Hazard and Risk Assessment Approaches for Endocrine-Active Substances (EHRA)’ was held from 31st January to 5th February 2016 in Pensacola, Florida, USA. The primary aim of the workshop was to provide objective advice, based on current s...

16 CFR 1500.5 - Hazardous mixtures.

Science.gov (United States)

2010-01-01

..., flammable, sensitizing, or pressure-generating properties of a substance from what is known about its... Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FEDERAL HAZARDOUS SUBSTANCES ACT REGULATIONS HAZARDOUS SUBSTANCES AND ARTICLES; ADMINISTRATION AND ENFORCEMENT REGULATIONS § 1500.5 Hazardous mixtures...

''Hazardous'' terminology

International Nuclear Information System (INIS)

Powers, J.

1991-01-01

A number of terms (e.g., ''hazardous chemicals,'' ''hazardous materials,'' ''hazardous waste,'' and similar nomenclature) refer to substances that are subject to regulation under one or more federal environmental laws. State laws and regulations also provide additional, similar, or identical terminology that may be confused with the federally defined terms. Many of these terms appear synonymous, and it easy to use them interchangeably. However, in a regulatory context, inappropriate use of narrowly defined terms can lead to confusion about the substances referred to, the statutory provisions that apply, and the regulatory requirements for compliance under the applicable federal statutes. This information Brief provides regulatory definitions, a brief discussion of compliance requirements, and references for the precise terminology that should be used when referring to ''hazardous'' substances regulated under federal environmental laws. A companion CERCLA Information Brief (EH-231-004/0191) addresses ''toxic'' nomenclature

46 CFR 151.03-30 - Hazardous material.

Science.gov (United States)

2010-10-01

... hazardous material means a liquid material or substance that is— (a) Flammable or combustible; (b) Designated a hazardous substance under section 311(b) of the Federal Water Pollution Control Act (33 U.S.C... Agency designates hazardous substances in 40 CFR Table 116.4A. The Coast Guard designates hazardous...

Comparison of the rationale used in setting occupational exposure standards for ionizing radiation and hazardous chemical substances

International Nuclear Information System (INIS)

Halton, D.M.

1986-12-01

Ten chemicals which create significant occupational hazard are reviewed. They are toluene diisocyanate, hydrogen fluoride, n-hexane, carbon disulphide, cadmium, inorganic mercury, cobalt, nitroglycerol, silica and vinyl chloride. Each is discussed under the headings of physiological intake and elimination in humans, characteristics of acute and chronic toxicity, sites of occupational exposure and rationale for limits of such exposure. Since radioactive substances yield ionizing radiation as the common hazard the treatment of the current permissible levels of exposure is somewhat simpler. Having set out industrial standards for exposure to hazardous substances and radionuclides, a detailed comparison is made. Exposure limits to ioninzing radiation are sufficiently low to remove the appearance of directly related injury. It is expected however that low level exposure may have a stochastic effect, that is, there is the possibility of a slightly increased incidence of neoplasms in a large exposed population, but numbers will be too small to be able to attribute any particular case to the exposure. TLVs on the other hand, depending on the particular chemical, may be high enough in the workplace to permit some directly related signs or symptoms in the exposed individual. 244 refs

Strategy for the investigation of hazardous substances in industrial effluents: IDA (Industrial Discharge Assessment)

Energy Technology Data Exchange (ETDEWEB)

Reemtsma, T.; Klinkow, N.

2001-08-01

The assessment of amounts and effects of hazardous substances in industrial effluents necessitates a combination of chemical and biological investigations. Therefore in this study a strategy for the investigation of hazardous substances in wastewater discharges was developed which connects the parameters persistence, bioaccumulation, and aquatic toxicity. The strategy IDA (Industrial Discharge Assessment) was elaborated based on the evaluation of existing investigation strategies and the available test systems. The strategy has a modular structure to assure a flexible investigation with regard to the particularities of a given wastewater. After the determination of acute and chronic toxicity and genotoxicity a microbial degradation test is carried out to obtain the persistent wastewater fraction. The bioaccumulating substances are determined from this fraction by solid-phase extraction. Within the strategy differences between direct and indirect discharges are taken into account and particulate matter is considered as well. By the modular linking it can be determined if a wastewater contains toxic and persistent and bioaccumulating substances, which present an important potential of hazard for the aquatic environment. The first application of the strategy on three wastewater samples of the chemical and the metal processing industry showed that the strategy can be used as planned. (orig.) [German] Die Erfassung der Gehalte und Wirkungen gefaehrlicher Stoffe in Abwassereinleitungen der Industrie erfordert eine Kombination chemischer und biologischer Untersuchungen, die ueber das bisher in der AbwV festgelegte Mass hinausgeht. In dieser Studie wurde deshalb eine Untersuchungsstrategie fuer gefaehrliche Stoffe in Abwasserleitungen entwickelt, die die Parameter Persistenz, Bioakkumulierbarkeit und Toxizitaet auch experimentell verknuepft. Die Ausarbeitung erfolgte nach Auswertung der international bestehenden Untersuchungsstrategien sowie der zur Verfuegung stehenden

Reporting releases of hazardous substances under CERCLA and EPCRA

International Nuclear Information System (INIS)

Dailey, R.

1990-04-01

Several federal environmental laws requires that ''release of hazardous substances to the environment'' above certain threshold amounts -- Reportable Quantities or RQs -- be reported. Current and proposed regulations under these statutes are unclear and make full compliance difficult. Nevertheless, failure to comply could result in civil or criminal penalties. In response to questions raised by several DOE Field Elements, this Information Brief is part of a series that will provide updated information on this and other CERCLA issues. The Environmental Guidance Division (EH-231) has responded to those questions relating the reporting of releases for which EPA has a clearly articulated position. EPA's position on other questions raised by Field Elements has been equivocal; DOE is working with EPA to resolve these outstanding issues. Additional information briefs on reporting releases will be issued as a clear position is defined

In vivo laser scanning microscopic investigation of the decontamination of hazardous substances from the human skin

International Nuclear Information System (INIS)

Lademann, J; Patzelt, A; Schanzer, S; Richter, H; Sterry, W; Gross, I; Menting, K H; Frazier, L; Antoniou, C

2010-01-01

The stimulation of the penetration of topically applied substances into the skin is a topic of intensive dermatological and pharmacological research. In this context, it was found that in addition to the intercellular penetration, the follicular penetration also represents an efficient penetration pathway. The hair follicles act as a long-term reservoir for topically applied substances. They are surrounded by all important target structures, such as blood capillaries, stem and dendritic cells. Therefore, the hair follicles, as well as the skin, need to be protected from hazardous substances. The traditional method of decontamination after respective accidental contacts consists of an intensive washing of the skin. However, during this mechanical procedure, the substances can be pushed even deeper into the hair follicles. In the present study, absorbent materials were applied to remove a fluorescent model substance from the skin without inducing mechanical stress. The results were compared to the decontamination effects obtained by intensive washing. Investigations were performed by means of in vivo laser scanning microscopy (LSM). The comparison revealed that decontamination with absorbent materials is more effective than decontamination with washing processes

Biological monitoring of organic substances in workers of a hazardous waste incinerator

Energy Technology Data Exchange (ETDEWEB)

Agramunt, C.; Domingo, J.L.; Bocio, A.; Nadal, M. [Lab. of Toxicology and Environmental Health, Reus (Spain); Muller, L. [SGS GmbH, Antwerpen (Belgium)

2004-09-15

In recent years, incineration has been one of the most frequently used technologies for hazardous waste treatment. However, health risks and the potential environmental impact of hazardous waste incinerators (HWI) are still issues of major concern. The reason is the association of stack emissions of semivolatile and volatile compounds from HWI with their potential adverse health effects. Some compounds of special interest are polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs). In relation to this, HWI workers can be potentially exposed to PCDD/Fs, polychlorinated biphenyls (PCBs) and other pollutants with a well-known toxicity. Since 1999, the only HWI in Spain has been operating in Constanti (Tarragona, Catalonia). It has a burning furnace that operates at a temperature of 1100 C and can burn 30,000 tons of hazardous waste per year. The purpose of the present survey was to determine after four years of regular operations in the facility, the concentrations in blood and urine of the HWI workers of a number of organic substances directly related with HWI and to which workers could be exposed. Human biological monitoring evaluates the degree of internal exposure to a defined environmental or occupational pollutant of individuals or population groups. The results of the current study have been compared with the baseline levels.

Remediation of sites with mixed contamination of radioactive and other hazardous substances

International Nuclear Information System (INIS)

2006-01-01

The IAEA attaches great importance to the dissemination of information that can assist Member States with the development, implementation, maintenance and continuous improvement of systems, programmes and activities that support the management of the legacies of past practices and accidents. In response to this, the IAEA has initiated a comprehensive programme of work covering all aspects of environmental remediation. Mixed radioactive and hazardous substances contamination poses a particular challenge because of the combination of types of hazards and potential exposures. While radionuclides and toxic (heavy) metals pose similar and mostly compatible challenges, organic contaminants often require different approaches that may not be compatible with the former. Additional complexity is introduced into the problem by a different and sometimes conflicting regulatory framework for radiological and non-radiological contamination, including the prescribed waste management routes. In consideration of the added complexities of remediating (mixed) contamination, the IAEA has determined that this subject sufficiently warrants the development of a specialized report for assisting Member States. Topics discussed are types of sites, hazards and contaminant behaviour; regulatory implications; implications for worker health and safety; implications for sampling and analysis; elements of the remediation process; technology evaluation and selection; monitored non-intervention; blocking of pathways; removal of the source term; ex-situ treatment followed by case studies and a glossary

Dog and Cat Exposures to Hazardous Substances Reported to the Kansas State Veterinary Diagnostic Laboratory: 2009–2012

OpenAIRE

Mahdi, Ali; Van der Merwe, Deon

2013-01-01

Pet dogs and cats in the USA are commonly exposed to potentially hazardous substances found in domestic environments. Requests for assistance and advice received by the Kansas State Veterinary Diagnostic Laboratory regarding exposures in dogs and cats to substances perceived by their caretakers to be potentially harmful included 1,616 phone calls, over a 3-year period covering 2009–2012. Enquiries occurred more often during summer. Dogs were involved in 84.7 % of calls and cats in 15.3 %. Ora...

Hazardous Waste

Science.gov (United States)

... chemicals can still harm human health and the environment. When you throw these substances away, they become hazardous waste. Some hazardous wastes come from products in our homes. Our garbage can include such hazardous wastes as old batteries, bug spray cans and paint thinner. U.S. residents ...

Transportation of hazardous goods

CERN Multimedia

TS Department

2008-01-01

A general reminder: any transportation of hazardous goods by road is subject to the European ADR rules. The goods concerned are essentially the following: Explosive substances and objects; Gases (including aerosols and non-flammable gases such as helium and nitrogen); Flammable substances and liquids (inks, paints, resins, petroleum products, alcohols, acetone, thinners); Toxic substances (acids, thinners); Radioactive substances; Corrosive substances (paints, acids, caustic products, disinfectants, electrical batteries). Any requests for the transport of hazardous goods must be executed in compliance with the instructions given at this URL: http://ts-dep.web.cern.ch/ts-dep/groups/he/HH/adr.pdf Heavy Handling Section TS-HE-HH 73793 - 160364

A Risk Assessment Model for Water Resources: releases of dangerous and hazardous substances.

Science.gov (United States)

Rebelo, Anabela; Ferra, Isabel; Gonçalves, Isolina; Marques, Albertina M

2014-07-01

Many dangerous and hazardous substances are used, transported and handled daily in diverse situations, from domestic use to industrial processing, and during those operations, spills or other anomalous situations may occur that can lead to contaminant releases followed by contamination of surface water or groundwater through direct or indirect pathways. When dealing with this problem, rapid, technically sound decisions are desirable, and the use of complex methods may not be able to deliver information quickly. This work describes a simple conceptual model established on multi-criteria based analysis involving a strategic appraisal for contamination risk assessment to support local authorities on rapid technical decisions. The model involves a screening for environmental risk sources, focussing on persistent, bioaccumulative and toxic (PBT) substances that may be discharged into water resources. It is a simple tool that can be used to follow-up actual accident scenarios in real time and to support daily activities, such as site-inspections. Copyright © 2014 Elsevier Ltd. All rights reserved.

Hazardous materials and toxic substances - Status report

International Nuclear Information System (INIS)

Sommerlad, R.E.

1991-01-01

The paper first forecasts what the status of hazardous wastes should be in the year 2028. The author believes all the problems will be solved: no new hazardous wastes will be being generated and the current hazardous waste problems will have been cleared up by common sense engineering. He then describes the current status of waste management of hazardous wastes, the regulatory situation, as well as combustion test programs

The hazardous priority substances in Italy: National rules and environmental quality standard in marine environment

International Nuclear Information System (INIS)

Maggi, Chiara; Onorati, Fulvio; Lamberti, Claudia Virno; Cicero, Anna Maria

2008-01-01

Article number 16 of the Water Framework Directive (Directive 2000/60/EC) lays down the community strategy for establishment of harmonised quality standards for the priority substances and other substances posing a significant risk to the aquatic environment. In order to achieve the protection objectives of the Directive 2000/60/EC, the Italian Ministry of the Environment proposed the quality standards for surface water, sediments and biota related to the priority substances listed in the decision No. 2455/2001/EC of the European Parliament and of the Council of November 20 (2001) [Decision N. 2455/2001/EC of the European Parliament and of the Council of 20 November 2001. The list of priority substances in the field of water policy and amending Directive 2000/60/EC. Official Journal of the European Communities, 15.12.2001, p. 5]. Particularly, for the protection of the marine environment, the proposed Italian rules state that, from 1 January 2021, the concentrations of the hazardous priority substances in Italian marine and lagoon waters must be near the natural background for natural substances, like metals, and near zero for the anthropogenic one. According to Directive 2000/60/EC, the Italian Ministry of Environment issued in 2003 Decree 367 in which has derived 160 Environmental Quality Standard (EQS) for water and 27 Environmental Quality Objective (EQO) for sediment of marine coastal area, lagoons and coastal ponds. Biota quality standards have still to be fixed. The paper illustrates the criteria applied for the definition of the quality standards and some comments are presented

Maintenance and hazardous substances

NARCIS (Netherlands)

Kuhl, K.; Terwoert, J.; Cabecas, J.J.M.

2012-01-01

Maintenance workers come into close contact with a broad variety of often hazardous chemicals. Depending on the specific type, these chemicals may not only cause diseases like skin sores or cancer, but many of them are highly flammable and explosive. This e-facts focuses on the specific risks

Hazardous Substance Release Reporting Under CERCLA, EPCR {section}304 and DOE Emergency Management System (EMS) and DOE Occurrence Reporting Requirements. Environmental Guidance

Energy Technology Data Exchange (ETDEWEB)

Traceski, T.T.

1994-06-01

Releases of various substances from DOE facilities may be subject to reporting requirements under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) and the Emergency Planning and Community Right-to-Know Act (EPCRA), as well as DOE`s internal ``Occurrence Reporting and Processing of Operations Information`` and the ``Emergency Management System`` (EMS). CERCLA and EPCPA are Federal laws that require immediate reporting of a release of a Hazardous Substance (HS) and an Extremely Hazardous Substance (EHS), respectively, in a Reportable Quantity (RQ) or more within a 24-hour period. This guidance uses a flowchart, supplemental information, and tables to provide an overview of the process to be followed, and more detailed explanations of the actions that must be performed, when chemical releases of HSs, EHSs, pollutants, or contaminants occur at DOE facilities. This guidance should be used in conjunction with, rather than in lieu of, applicable laws, regulations, and DOE Orders. Relevant laws, regulations, and DOE Orders are referenced throughout this guidance.

Federal regulation on the handling of substances constituting a hazard to water; Bundeseinheitliche Regelung des Umgangs mit wassergefaehrdenden Stoffen

Energy Technology Data Exchange (ETDEWEB)

Hollaender, Robert; Unnerstall, Herwig; Skiba, Katja; Katscher, Henriette; Kochmann, Linda; Enderlein, Frank [Leipzig Univ. (Germany). Professur fuer Umwelttechnik und -management; Helmholtzzentrum fuer Umweltforschung - ufz, Leipzig (Germany). Dept. Umwelt- und Planungsrecht; Sachverstaendigenorganisation AGU-TSO e.V., Bergen b. Auerbach (Germany)

2010-03-15

Subject of the research project was preliminary work for a draft of the federal ordinance on the handling of substances constituting a hazard to water. Basis was the draft for an Environmental Code by the Federal Ministry for the Environment from 25. June 2007 and 03. July 2008, Part II on water management. This report includes an analysis of the existing ordinances of the Laender (to be replaced by the new federal ordinance), a survey on problems with their enforcement, an analysis of European Directives on relevant implementation requirements, an analysis of the relation to the legislation on construction products, a comparison to regulations of other European Countries for the protection of water against hazardous substances, an approach for obligations of an ordinance, a preliminary draft of an ordinance, a concept for a system of related Technical Rules and finally an evaluation of possible costs of operators and of additional tasks of authorities due to obligations in the preliminary draft. (orig.)

The evaluation of an analytical protocol for the determination of substances in waste for hazard classification

Energy Technology Data Exchange (ETDEWEB)

Hennebert, Pierre, E-mail: pierre.hennebert@ineris.fr [INERIS – Institut National de l’Environnement Industriel et des Risques, Domaine du Petit Arbois BP33, F-13545 Aix-en-Provence (France); Papin, Arnaud [INERIS, Parc Technologique ALATA, BP No. 2, 60550 Verneuil en Halatte (France); Padox, Jean-Marie [INERIS – Institut National de l’Environnement Industriel et des Risques, Domaine du Petit Arbois BP33, F-13545 Aix-en-Provence (France); Hasebrouck, Benoît [INERIS, Parc Technologique ALATA, BP No. 2, 60550 Verneuil en Halatte (France)

2013-07-15

Highlights: • Knowledge of wastes in substances will be necessary to assess HP1–HP15 hazard properties. • A new analytical protocol is proposed for this and tested by two service laboratories on 32 samples. • Sixty-three percentage of the samples have a satisfactory analytical balance between 90% and 110%. • Eighty-four percentage of the samples were classified identically (Seveso Directive) for their hazardousness by the two laboratories. • The method, in progress, is being normalized in France and is be proposed to CEN. - Abstract: The classification of waste as hazardous could soon be assessed in Europe using largely the hazard properties of its constituents, according to the the Classification, Labelling and Packaging (CLP) regulation. Comprehensive knowledge of the component constituents of a given waste will therefore be necessary. An analytical protocol for determining waste composition is proposed, which includes using inductively coupled plasma (ICP) screening methods to identify major elements and gas chromatography/mass spectrometry (GC–MS) screening techniques to measure organic compounds. The method includes a gross or indicator measure of ‘pools’ of higher molecular weight organic substances that are taken to be less bioactive and less hazardous, and of unresolved ‘mass’ during the chromatography of volatile and semi-volatile compounds. The concentration of some elements and specific compounds that are linked to specific hazard properties and are subject to specific regulation (examples include: heavy metals, chromium(VI), cyanides, organo-halogens, and PCBs) are determined by classical quantitative analysis. To check the consistency of the analysis, the sum of the concentrations (including unresolved ‘pools’) should give a mass balance between 90% and 110%. Thirty-two laboratory samples comprising different industrial wastes (liquids and solids) were tested by two routine service laboratories, to give circa 7000 parameter

Uncertainties in biological responses that influence hazard and risk approaches to the regulation of endocrine active substances.

Science.gov (United States)

Parrott, Joanne L; Bjerregaard, Poul; Brugger, Kristin E; Gray, L Earl; Iguchi, Taisen; Kadlec, Sarah M; Weltje, Lennart; Wheeler, James R

2017-03-01

Endocrine-disrupting substances (EDS) may have certain biological effects including delayed effects, multigenerational effects, and may display nonmonotonic dose-response (NMDR) relationships that require careful consideration when determining environmental hazards. Endocrine disrupting substances can have specific and profound effects when exposure occurs during sensitive windows of the life cycle (development, reproduction). This creates the potential for delayed effects that manifest when exposure has ceased, possibly in a different life stage. This potential underscores the need for testing in appropriate (sensitive) life stages and full life cycle designs. Such tests are available in the Organisation for Economic Co-operation and Development (OECD) tool box and should be used to derive endpoints that can be considered protective of all life stages. Similarly, the potential for effects to be manifest in subsequent generations (multigenerational effects) has also been raised as a potential issue in the derivation of appropriate endpoints for EDS. However, multigenerational studies showing increasing sensitivity of successive generations are uncommon. Indeed this is reflected in the design of new higher tier tests to assess endocrine active substances (EAS) that move to extended one-generation designs and away from multi-generational studies. The occurrence of NMDRs is also considered a limiting factor for reliable risk assessment of EDS. Evidence to date indicates NMDRs are more prevalent in in vitro and mechanistic data, not often translating to adverse apical endpoints that would be used in risk assessment. A series of steps to evaluate NMDRs in the context of endocrine hazard and risk assessment procedures is presented. If careful consideration of delayed, multigenerational effects and NMDRs is made, it is feasible to assess environmental endocrine hazards and derive robust apical endpoints for risk assessment procedures ensuring a high level of environmental

78 FR 9311 - Hazard Communication; Corrections and Technical Amendment

Science.gov (United States)

2013-02-08

....1044, Appendix Reference to ``Class IIIA combustible B. liquid'' is corrected to ``Category 4 flammable..., Fire prevention, Hazard communication, Hazardous substances, Occupational safety and health. 29 CFR... Asbestos, Construction industry, Fire prevention, Hazardous substances, Occupational safety and health...

Hazardous Substances Data Bank (HSDB)

Data.gov (United States)

U.S. Department of Health & Human Services — Comprehensive, peer-reviewed toxicology data for about 5,000 chemicals. The data bank focuses on the toxicology of potentially hazardous chemicals. It is enhanced...

The relevance of national and international initiatives on toxic substances to the management of hazardous air pollutants in Canada

Energy Technology Data Exchange (ETDEWEB)

Buccini, J.

2001-03-30

The Canadian Council of Ministers of the Environment (CCME), seeking guidance on current and emerging national and international initiatives, activities, and programs that could impact on the management of hazardous air pollutants (HAPs) in Canada, commissioned the author to prepare this document. In this report, HAPs are defined as toxic substances subject to airborne transport as a significant route of environmental distribution and/or exposure. Heavy metals and persistent organic pollutants (POPs) were included in this definition. A model, known as toxics cycle, represented the four distinct stages of the process of selecting substances for risk assessment and management: problem identification and priority setting, risk assessment, risk management, and monitoring and evaluation. A large number of international activities were reviewed, such as research, hazard and risk assessment, risk management, and monitoring and surveillance programs. The present report only deals with the programs that had been identified in the National Air Issues Coordinating Committee-Other Air Issues (NAICC-A) of the CCME report published in 1999 and which had recent or foreseen impacts. Five bi-lateral and multi-lateral agreements on persistent toxic substances, as well as national, regional and global programs, activities, and initiatives concerning the assessment of the hazards and risks of chemicals and actions were reviewed. It was recommended that initiatives at all levels continue to be monitored and that Environment Canada continue to be the conduit of information at the international level. Issues and opportunities must be identified by all jurisdictions with regard to risk management. It was suggested by the author that risk assessment be conducted by Environment Canada and the attention of the HAP group be drawn on specific topics as required. 2 tabs., 1 fig.

Restriction of the use of hazardous substances (RoHS in the personal computer segment: analysis of the strategic adoption by the manufacturers settled in Brazil

Directory of Open Access Journals (Sweden)

Ademir Brescansin

2015-09-01

Full Text Available The enactment of the RoHS Directive (Restriction of Hazardous Substances in 2003, limiting the use of certain hazardous substances in electronic equipment has forced companies to adjust their products to comply with this legislation. Even in the absence of similar legislation in Brazil, manufacturers of personal computers which are located in this country have been seen to adopt RoHS for products sold in the domestic market and abroad. The purpose of this study is to analyze whether these manufacturers have really adopted RoHS, focusing on their motivations, concerns, and benefits. This is an exploratory study based on literature review and interviews with HP, Dell, Sony, Lenovo, Samsung, LG, Itautec, and Positivo, using summative content analysis. The results showed that initially, global companies adopted RoHS to market products in Europe, and later expanded this practice to all products. Brazilian companies, however, adopted RoHS to participate in the government’s sustainable procurement bidding processes. It is expected that this study can assist manufacturers in developing strategies for reducing or eliminating hazardous substances in their products and processes, as well as help the government to formulate public policies on reducing risks of environmental contamination.

Work environments and exposure to hazardous substances in korean tire manufacturing.

Science.gov (United States)

Lee, Naroo; Lee, Byung-Kyu; Jeong, Sijeong; Yi, Gwang Yong; Shin, Jungah

2012-06-01

The purpose of this study is to evaluate the tire manufacturing work environments extensively and to identify workers' exposure to hazardous substances in various work processes. Personal air sampling was conducted to measure polycyclic aromatic hydrocarbons, carbon disulfide, 1,3-butadiene, styrene, methyl isobutyl ketone, methylcyclohexane, formaldehyde, sulfur dioxide, and rubber fume in tire manufacturing plants using the National Institute for Occupational Safety Health Manual of Analytical Methods. Noise, carbon monoxide, and heat stress exposure were evaluated using direct reading instruments. Past concentrations of rubber fume were assessed using regression analysis of total particulate data from 2003 to 2007, after identifying the correlation between the concentration of total particulate and rubber fume. Workers were exposed to rubber fume that exceeded 0.6 mg/m(3), the maximum exposure limit of the UK, in curing and production management processes. Forty-seven percent of workers were exposed to noise levels exceeding 85 dBA. Workers in the production management process were exposed to 28.1℃ (wet bulb globe temperature value, WBGT value) even when the outdoor atmosphere was 2.7℃ (WBGT value). Exposures to other substances were below the limit of detection or under a tenth of the threshold limit values given by the American Conference of Governmental Industrial Hygienists. To better classify exposure groups and to improve work environments, examining closely at rubber fume components and temperature as risk indicators in tire manufacturing is recommended.

Overview of major hazards. Part 2: Source term; dispersion; combustion; blast, missiles, venting; fire; radiation; runaway reactions; toxic substances; dust explosions

Science.gov (United States)

Vilain, J.

Approaches to major hazard assessment and prediction are reviewed. Source term: (phenomenology/modeling of release, influence on early stages of dispersion); dispersion (atmospheric advection, diffusion and deposition, emphasis on dense/cold gases); combustion (flammable clouds and mists covering flash fires, deflagration, transition to detonation; mostly unconfined/partly confined situations); blast formation, propagation, interaction with structures; catastrophic fires (pool fires, torches and fireballs; highly reactive substances) runaway reactions; features of more general interest; toxic substances, excluding toxicology; and dust explosions (phenomenology and protective measures) are discussed.

The National Library of Medicine's (NLM) Hazardous Substances Data Bank (HSDB): background, recent enhancements and future plans.

Science.gov (United States)

Fonger, George Charles; Hakkinen, Pertti; Jordan, Shannon; Publicker, Stephanie

2014-11-05

The National Library of Medicine's (NLM) Division of Specialized Information Services (SIS) Toxicology and Environmental Health Information Program is responsible for the management of the online Hazardous Substances Data Bank (HSDB). HSDB, a part of NLM's Toxicology Data Network (TOXNET(®)), is a file of chemical/substance information with one record for each specific chemical or substance, or for a category of chemicals or substances. Like the rest of TOXNET's databases and other resources, HSDB is available online at no cost to global users. HSDB has approximately 5600 chemicals and substances, with a focus on toxicology information and also on human exposure, industrial hygiene, emergency handling procedures, environmental fate, regulatory requirements, and related areas of likely interest to HSDB users. All data are from a core set of books, government documents, technical reports, selected primary journal literature, and other online sources of information, with a goal of linking the HSDB content to as much publicly available information as possible. HSDB's content is peer-reviewed by the Scientific Review Panel, a group of experts in the areas covering the scope of HSDB content. Recent enhancements include the addition of chemical structures to HSDB records, the addition of new subfields such as age groups for human data, more occupational exposure standards, and the addition of information on numerous nanomaterials. Examples of future plans include providing more exposure-related information, e.g., uses of a chemical or substance in consumer products; the addition of information summaries aimed towards consumers and other members of the public wanting to learn about a chemical or substance; more visual content such as diagrams (images) of the pathways of metabolism of a substance; and enhanced search features and navigation. Published by Elsevier Ireland Ltd.

Development of a Hazard Classification Scheme for Substances Used in the Fraudulent Adulteration of Foods.

Science.gov (United States)

Everstine, Karen; Abt, Eileen; McColl, Diane; Popping, Bert; Morrison-Rowe, Sara; Lane, Richard W; Scimeca, Joseph; Winter, Carl; Ebert, Andrew; Moore, Jeffrey C; Chin, Henry B

2018-01-01

Food fraud, the intentional misrepresentation of the true identity of a food product or ingredient for economic gain, is a threat to consumer confidence and public health and has received increased attention from both regulators and the food industry. Following updates to food safety certification standards and publication of new U.S. regulatory requirements, we undertook a project to (i) develop a scheme to classify food fraud-related adulterants based on their potential health hazard and (ii) apply this scheme to the adulterants in a database of 2,970 food fraud records. The classification scheme was developed by a panel of experts in food safety and toxicology from the food industry, academia, and the U.S. Food and Drug Administration. Categories and subcategories were created through an iterative process of proposal, review, and validation using a subset of substances known to be associated with the fraudulent adulteration of foods. Once developed, the scheme was applied to the adulterants in the database. The resulting scheme included three broad categories: 1, potentially hazardous adulterants; 2, adulterants that are unlikely to be hazardous; and 3, unclassifiable adulterants. Categories 1 and 2 consisted of seven subcategories intended to further define the range of hazard potential for adulterants. Application of the scheme to the 1,294 adulterants in the database resulted in 45% of adulterants classified in category 1 (potentially hazardous). Twenty-seven percent of the 1,294 adulterants had a history of causing consumer illness or death, were associated with safety-related regulatory action, or were classified as allergens. These results reinforce the importance of including a consideration of food fraud-related adulterants in food safety systems. This classification scheme supports food fraud mitigation efforts and hazard identification as required in the U.S. Food Safety Modernization Act Preventive Controls Rules.

Process for determining the remediation category of hazardous substance sites

International Nuclear Information System (INIS)

Sieben, A.K.

1994-01-01

An evaluation process has been developed that aids in selecting the appropriate remediation category of hazardous substance sites. Three general remediation categories have been established: No further Action: Potential Early Action: and Defer for RI/FS or Transition/Decontamination and Decommissioning. This evaluation method is a preliminary screening process only and will not identify the most appropriate remediation alternative for each site. The remedy selection process can proceed only after a remediation category is determined for each site. All sites are evaluated at a preliminary screening level to determine the general remediation category. After the first screen, a secondary evaluation is performed on both the PEA sites and the DEFER sites. For PEAs, this secondary evaluation will incorporate additional specific factors, such as a screening level risk assessment. For the DEFER sites feasibility factors will be used to distinguish between the sites which should undergo a normal RI/FS and the sites which will be recommended to be remediated in association with D ampersand D of buildings. Ultimately, all of the sites will be placed into one of four remediation categories

Transportation of Hazardous Evidentiary Material.

Energy Technology Data Exchange (ETDEWEB)

Osborn, Douglas.

2005-06-01

This document describes the specimen and transportation containers currently available for use with hazardous and infectious materials. A detailed comparison of advantages, disadvantages, and costs of the different technologies is included. Short- and long-term recommendations are also provided.3 DraftDraftDraftExecutive SummaryThe Federal Bureau of Investigation's Hazardous Materials Response Unit currently has hazardous material transport containers for shipping 1-quart paint cans and small amounts of contaminated forensic evidence, but the containers may not be able to maintain their integrity under accident conditions or for some types of hazardous materials. This report provides guidance and recommendations on the availability of packages for the safe and secure transport of evidence consisting of or contaminated with hazardous chemicals or infectious materials. Only non-bulk containers were considered because these are appropriate for transport on small aircraft. This report will addresses packaging and transportation concerns for Hazardous Classes 3, 4, 5, 6, 8, and 9 materials. If the evidence is known or suspected of belonging to one of these Hazardous Classes, it must be packaged in accordance with the provisions of 49 CFR Part 173. The anthrax scare of several years ago, and less well publicized incidents involving unknown and uncharacterized substances, has required that suspicious substances be sent to appropriate analytical laboratories for analysis and characterization. Transportation of potentially hazardous or infectious material to an appropriate analytical laboratory requires transport containers that maintain both the biological and chemical integrity of the substance in question. As a rule, only relatively small quantities will be available for analysis. Appropriate transportation packaging is needed that will maintain the integrity of the substance, will not allow biological alteration, will not react chemically with the substance being

Study on hazardous substances contained in radioactive waste

International Nuclear Information System (INIS)

Kuroki, Ryoichiro; Takahashi, Kuniaki

2008-01-01

It is necessary that the technical criteria is established concerning waste package for disposal of the TRU waste generated in Japan Atomic Energy Agency. And it is important to consider the criteria not only in terms of radioactivity but also in terms of chemical hazard and criticality. Therefore the environmental impact of hazardous materials and possibility of criticality were investigated to decide on technical specification of radioactive waste packages. The contents and results are as following. (1) Concerning hazardous materials included in TRU waste, regulations on disposal of industrial wastes and on environmental preservation were investigated. (2) The assessment methods for environmental impact of hazardous materials included in radioactive waste in U.K, U.S.A. and France were investigated. (3) The parameters for mass transport assessment about migration of hazardous materials in waste packages around disposal facilities were compiled. And the upper limits of amounts of hazardous materials in waste packages to satisfy the environmental standard were calculated with mass transport assessment for some disposal concepts. (4) It was suggested from criticality analysis for waste packages in disposal facility that the occurrence of criticality was almost impossible under the realistic conditions. (author)

Development of a unified federal/state coastal/inland oil and hazardous substance contingency plan for the state of Alaska

International Nuclear Information System (INIS)

Lautenberger, C.; Pearson, L.

1993-01-01

Passage of the US Oil Pollution Act (OPA) of 1990 expanded the existing federal planning and response framework in several ways. The OPA created a new requirement for facility and tank vessel response plans and creates an area-level planning and coordination structure to help supplement federal, regional, and local planning efforts. The OPA amended the existing Clean Water Act's section 311(j)(4), which establishes area committees and area contingency plans as primary components of this structure. In 1980, the Alaska legislature enacted legislation which defines the state's policies regarding oil spills. Following the 1989 Exxon Valdez spill, additional legislation was passed to expand and strengthen the state's oil spill program. Specifically, in 1989 the Senate Bill 261 required the Alaska Department of Environmental Conservation to develop, annually review, and revise the State Oil and Hazardous Substance Contingency Plans (State Master and Regional Plans). State regional plans serve as annexes to the State Master Plan. The coordinated and cooperative efforts by government agencies and local entities toward creating a unified federal/state, coastal/inland Oil and Hazardous Substance Contingency Plan are presented, along with the development and progress of unified area/regional contingency plans for Alaska. 3 figs

30 CFR 47.21 - Identifying hazardous chemicals.

Science.gov (United States)

2010-07-01

..., subpart Z, Toxic and Hazardous Substances. (4) American Conference of Governmental Industrial Hygienists... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Identifying hazardous chemicals. 47.21 Section... TRAINING HAZARD COMMUNICATION (HazCom) Hazard Determination § 47.21 Identifying hazardous chemicals. The...

Methodology for environmental assessments of oil and hazardous substance spills

Science.gov (United States)

Davis, W. P.; Scott, G. I.; Getter, C. D.; Hayes, M. O.; Gundlach, E. R.

1980-03-01

Scientific assessment of the complex environmental consequences of large spills of oil or other hazardous substances has stimulated development of improved strategies for rapid and valid collection and processing of ecological data. The combination of coastal processes and geological measurements developed by Hayes & Gundlach (1978), together with selected field biological and chemical observations/measurements, provide an ecosystem impact assessment approach which is termed “integrated zonal method of ecological impact assessment.” Ecological assessment of oil and hazardous material spills has been divided into three distinct phases: (1) first-order response studies — conducted at the time of the initial spill event, which gather data to document acute impacts and assist decision-makers in prioritization of cleanup efforts and protection of ecologically sensitive habitats, (2) second-order response studies — conducted two months to one year post-spill, which document any delayed mortality and attempt to identify potential sublethal impacts in sensitive species, and (3) third-order response studies — conducted one to three years post-spill, to document chronic impacts (both lethal and sublethal) to specific indicator species. Data collected during first-order response studies are gathered in a quantitative manner so that the initial assessment may become a baseline for later, more detailed, post-spill scientific efforts. First- and second-order response studies of the “Peck Slip” oil spill in Puerto Rico illustrate the usefulness of this method. The need for contingency planning before a spill has been discussed along with the use of the Vulnerability Index, a method in which coastal environments are classified on a scale of 1 10, based upon their potential susceptibility to oiling. A study of the lower Cook Inlet section of the Alaskan coast illustrates the practical application of this method.

Hazards of Illicit Methamphetamine Production and Efforts at Reduction: Data from the Hazardous Substances Emergency Events Surveillance System

Science.gov (United States)

Melnikova, Natalia; Welles, Wanda Lizak; Wilburn, Rebecca E.; Rice, Nancy; Wu, Jennifer; Stanbury, Martha

2011-01-01

Objectives. Methamphetamine (meth) is a highly addictive drug of abuse that can easily be made in small illegal laboratories from household chemicals that are highly toxic and dangerous. Meth labs have been found in locations such as homes, outbuildings, motels, and cars. Its production endangers the “cook,” neighbors, responders, and the environment. This article describes surveillance data used to examine the emergence and public health impacts of illicit clandestine meth labs, as well as two states' efforts to thwart lab operations and prevent responder injuries. Methods. We analyzed data collected from 2001 to 2008 by 18 states participating in the Agency for Toxic Substances and Disease Registry's Hazardous Substances Emergency Events Surveillance (HSEES) Program to examine the occurrence and public health impacts of clandestine meth production. Results. HSEES data indicate that the majority of clandestine meth lab events occurred in residential areas. About 15% of meth lab events required evacuation. Nearly one-fourth of these events resulted in injuries, with 902 reported victims. Most victims (61%) were official responders, and one-third were members of the general public. Since 2004, with the implementation of local and federal laws and prevention activities, the number of meth lab events has declined. Increased education and training of first responders has led to decreased injuries among police officers, firefighters, and emergency medical personnel. Conclusions. HSEES data provided a good data source for monitoring the emergence of domestic clandestine meth production, the associated public health effects, and the results of state and federal efforts to promote actions to address the problem. PMID:21563719

Analysis of the utilization of existing test data for phase-in substance registration under the Act on the Registration and Evaluation, etc. of Chemical Substances.

Science.gov (United States)

Choi, Bong-In; Kwak, Yeong-Don; Jung, Yu-Mi; Ryu, Byung-Taek; Kim, Chang Gyun

2015-01-01

Approximately 2000 phase-in substances are subject to registration according to the Act on the Registration and Evaluation, etc. of Chemical Substances (KREACH), and the expected testing cost is 2.06 trillion Korean won assuming all the test data required for registration are acquired. The extent to which these enormous test costs can be reduced depends on the availability of existing data that can be used to meet the requirements of the K-REACH we examined the current availability of test data that can be used for chemical substance registration. We analyzed the possibility of utilizing the existing test data obtained from 16 reference databases for 369 of 518 kinds of phase-in substances subject to registration that were reported in last October 2014. The physical and chemical properties were available for 57.1% of substances, whereas data regarding human hazards and environmental hazards were available at considerably lower rates, 8.5% and 11.8%, respectively. Physical and chemical properties were available for a fairly high proportion, whereas human hazards and environmental hazards were reported for considerably fewer substances.

Modified hazard ranking system for sites with mixed radioactive and hazardous wastes. User manual

International Nuclear Information System (INIS)

Hawley, K.A.; Peloquin, R.A.; Stenner, R.D.

1986-04-01

This document describes both the original Hazard Ranking System and the modified Hazard Ranking System as they are to be used in evaluating the relative potential for uncontrolled hazardous substance facilities to cause human health or safety problems or ecological or environmental damage. Detailed instructions for using the mHRS/HRS computer code are provided, along with instructions for performing the calculations by hand. Uniform application of the ranking system will permit the DOE to identify those releases of hazardous substances that pose the greatest hazard to humans or the environment. However, the mHRS/HRS by itself cannot establish priorities for the allocation of funds for remedial action. The mHRS/HRS is a means for applying uniform technical judgment regarding the potential hazards presented by a facility relative to other facilities. It does not address the feasibility, desirability, or degree of cleanup required. Neither does it deal with the readiness or ability of a state to carry out such remedial action, as may be indicated, or to meet other conditions prescribed in CERCLA. 13 refs., 13 figs., 27 tabs

Modified hazard ranking system for sites with mixed radioactive and hazardous wastes. User manual.

Energy Technology Data Exchange (ETDEWEB)

Hawley, K.A.; Peloquin, R.A.; Stenner, R.D.

1986-04-01

This document describes both the original Hazard Ranking System and the modified Hazard Ranking System as they are to be used in evaluating the relative potential for uncontrolled hazardous substance facilities to cause human health or safety problems or ecological or environmental damage. Detailed instructions for using the mHRS/HRS computer code are provided, along with instructions for performing the calculations by hand. Uniform application of the ranking system will permit the DOE to identify those releases of hazardous substances that pose the greatest hazard to humans or the environment. However, the mHRS/HRS by itself cannot establish priorities for the allocation of funds for remedial action. The mHRS/HRS is a means for applying uniform technical judgment regarding the potential hazards presented by a facility relative to other facilities. It does not address the feasibility, desirability, or degree of cleanup required. Neither does it deal with the readiness or ability of a state to carry out such remedial action, as may be indicated, or to meet other conditions prescribed in CERCLA. 13 refs., 13 figs., 27 tabs.

75 FR 78918 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Removal of...

Science.gov (United States)

2010-12-17

... and Community Right-to-Know Act FDA Food and Drug Administration HSWA Hazardous and Solid Waste...(f)), and hazardous substances (40 CFR 302.4) based solely upon the evidence that it is a potential... subsequently identified as hazardous wastes in Sec. 261.33(f) based solely on their potential for carcinogenic...

Effects of major depression on remission and relapse of substance dependence.

Science.gov (United States)

Hasin, Deborah; Liu, Xinhua; Nunes, Edward; McCloud, Steven; Samet, Sharon; Endicott, Jean

2002-04-01

The effects of major depressive disorder (MDD) on the course of substance dependence may differ depending on the temporal relationship of depression to dependence. We investigated the effects of MDD on the outcome of substance dependence under 3 circumstances: (1) lifetime onset of MDD prior to lifetime onset of dependence onset, (2) current MDD occurring during a period of abstinence, and (3) current MDD during substance use that exceeded the expected effects of intoxication or withdrawal. A sample of 250 inpatients with DSM-IV cocaine, heroin, and/or alcohol dependence were followed up at 6, 12, and 18 months. The Psychiatric Research Interview for Substance and Mental Disorders (PRISM) was used to make DSM-IV diagnoses. Using Cox proportional hazards models, stable remissions (those lasting at least 26 weeks) from DSM-IV cocaine, heroin, and/or alcohol dependence and from use were studied, as well as subsequent relapses of dependence and use. Patients with current substance-induced MDD were less likely to remit from dependence (adjusted hazards ratio, 0.11) than patients with no baseline MDD. A history of MDD prior to lifetime onset of substance dependence also reduced the likelihood of remission relative to the absence of such a history (adjusted hazard ratio, 0.49). Major depressive disorder during sustained abstinence predicted dependence relapse (adjusted hazards ratio, 3.07) and substance use after hospital discharge compared with those without abstinence MDD (adjusted hazards ratio, 1.45). The timing of depressive episodes relative to substance dependence served as an important factor in the remission and relapse of substance dependence and substance use.

77 FR 60935 - Hazardous Materials: Minor Editorial Corrections and Clarifications (RRR)

Science.gov (United States)

2012-10-05

... flammable cryogenic liquid is not received by the consignee within 20 days from the date of shipment.... * * * * * Container ship * * * * * * * * Hazardous material means a substance or material that the Secretary of... transportation law (49 U.S.C. 5103). The term includes hazardous substances, hazardous wastes, marine pollutants...

Hazardous materials

Science.gov (United States)

... substances that could harm human health or the environment. Hazardous means dangerous, so these materials must be ... M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health ...

Toxicology primer: understanding workplace hazards and protecting worker health.

Science.gov (United States)

Arble, Janice

2004-06-01

Hazardous substances are ubiquitous in the environment and common in industrialized societies. Serious harm can occur with sufficient exposures under certain conditions. However, much harm can be avoided if hazardous substances are handled with respect and appreciation for their use and potential. Occupational health nurses must be aware of potential hazards to employees in the work environment and apply scientific principles to their practice of promoting worker safety and health.

Managing hazardous activities and substances

International Nuclear Information System (INIS)

Morgenroth, V.H.

1994-01-01

The primary purpose of this paper is to provide background information on the process, principles and policies being employed in OECD Member Countries for managing hazardous activities (non-nuclear) and products involving chemicals (non-radioactive). In addition, the author highlights certain areas in the risk management process where certain assumptions and conclusions may be of particular relevance to the goal of a review, reconsideration and restatement of the strategy of geological disposal of radioactive wastes. (O.L.)

Hazard classification or risk assessment

DEFF Research Database (Denmark)

Hass, Ulla

2013-01-01

The EU classification of substances for e.g. reproductive toxicants is hazard based and does not to address the risk suchsubstances may pose through normal, or extreme, use. Such hazard classification complies with the consumer's right to know. It is also an incentive to careful use and storage...

Dog and cat exposures to hazardous substances reported to the Kansas State Veterinary Diagnostic Laboratory: 2009-2012.

Science.gov (United States)

Mahdi, Ali; Van der Merwe, Deon

2013-06-01

Pet dogs and cats in the USA are commonly exposed to potentially hazardous substances found in domestic environments. Requests for assistance and advice received by the Kansas State Veterinary Diagnostic Laboratory regarding exposures in dogs and cats to substances perceived by their caretakers to be potentially harmful included 1,616 phone calls, over a 3-year period covering 2009-2012. Enquiries occurred more often during summer. Dogs were involved in 84.7 % of calls and cats in 15.3 %. Oral exposures were reported in 95.5 % of calls, dermal exposures in 3.7 % of calls, inhalation exposures in 0.6 % of calls, and parenteral exposures in 0.2 % of calls. Therapeutic drugs were the most frequently reported substances, accounting for 35.4 % of calls, followed by household chemicals (15.5 %); foods (14.8 %); pesticides (13.9 %); plants (12 %), industrial chemicals and fertilizers (3.6 %); cosmetics and personal care products (2.8 %); and animal, insect, and microorganism toxins (2.1 %). Although requests for information or assistance are not a measure of poisoning incidence, it can provide insight regarding relative exposure rates, help to identify changing exposure trends and emerging exposures, and reflect the public concern regarding actual or apparent harmful exposures in pets.

40 CFR 68.50 - Hazard review.

Science.gov (United States)

2010-07-01

... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CHEMICAL ACCIDENT PREVENTION PROVISIONS Program 2 Prevention Program § 68.50 Hazard review. (a) The owner or operator shall conduct a review of the hazards associated with the regulated substances, process, and...

Analysis of hazardous substances released during CFRP laser processing

Science.gov (United States)

Hustedt, Michael; Walter, Juergen; Bluemel, Sven; Jaeschke, Peter; Kaierle, Stefan

2017-02-01

Due to their outstanding mechanical properties, in particular their high specific strength parallel to the carbon fibers, carbon fiber reinforced plastics (CFRP) have a high potential regarding resource-efficient lightweight construction. Consequently, these composite materials are increasingly finding application in important industrial branches such as aircraft, automotive and wind energy industry. However, the processing of these materials is highly demanding. On the one hand, mechanical processing methods such as milling or drilling are sometimes rather slow, and they are connected with notable tool wear. On the other hand, thermal processing methods are critical as the two components matrix and reinforcement have widely differing thermophysical properties, possibly leading to damages of the composite structure in terms of pores or delamination. An emerging innovative method for processing of CFRP materials is the laser technology. As principally thermal method, laser processing is connected with the release of potentially hazardous, gaseous and particulate substances. Detailed knowledge of these process emissions is the basis to ensure the protection of man and the environment, according to the existing legal regulations. This knowledge will help to realize adequate protective measures and thus strengthen the development of CFRP laser processing. In this work, selected measurement methods and results of the analysis of the exhaust air and the air at the workplace during different laser processes with CFRP materials are presented. The investigations have been performed in the course of different cooperative projects, funded by the German Federal Ministry of Education and Research (BMBF) in the course of the funding initiative "Photonic Processes and Tools for Resource-Efficient Lightweight Structures".

An ecodesign method for reducing the effects of hazardous substances in the product lifecycle

Science.gov (United States)

Simanovska, J.; Valters, K.; Bažbauers, G.; Luttropp, C.

2012-10-01

Growing evidence on the indoor and outdoor pollution caused by the flow of man-made products urges that the content and leaching of hazardous substances from products be minimised. One of the ways to reduce the potential adverse impacts caused by these substances could be via ecodesign - i.e. through the consideration of lifecycle-related environmental aspects during the product development. The authors’ review of the existing ecodesign methods highlights the weakness of these methods in identifying and assessing the health-related and environmental impacts of hazardous substances contained in products, especially with regard to the exposure assessment. Therefore, a new, semi-quantitative screening ecodesign method applicable for different types of products has been developed. The method ranks the most severe hazards based on the classification according to the Globally Harmonised System together with the exposure evaluation as well as integrates the aspects of material efficiency. This method is suitable for use in the product development process, requiring decisions to be made based on limited information while integrating the main principles of a scientific risk assessment for chemicals. Application of the method is demonstrated with a case study on products made of plywood. The method makes it possible to identify the needs for and elaboration of ecodesign proposals, and fosters communication and information exchange throughout the supply chain. Augošs pierādījumu daudzums par produktu sastāvā esošo kaitīgo ķīmisko vielu nelabvēlīgo ietekmi uz vidi un cilvēku veselību liecina par nepieciešamību samazināt šādu vielu saturu produktos un izdalīšanos no tiem, ko varētu realizēt ar ekodizaina palīdzību. Pārskatot zinātniskās publikācijas ekodizaina jomā, konstatēts, ka pašreiz ekodizaina metodes nepilnīgi nodrošina materiālu sastāvā esošo vielu kaitīgās ietekmes uz cilvēku veselību un apkārtējo vidi novēršanu. T�

Surveillance of Washington OSHA exposure data to identify uncharacterized or emerging occupational health hazards.

Science.gov (United States)

Lofgren, Don J; Reeb-Whitaker, Carolyn K; Adams, Darrin

2010-07-01

Chemical substance exposure data from the Washington State Occupational Safety and Health Administration (OSHA) program were reviewed to determine if inspections conducted as a result of a report of a hazard from a complainant or referent may alert the agency to uncharacterized or emerging health hazards. Exposure and other electronically stored data from 6890 health inspection reports conducted between April 2003 and August 2008 were extracted from agency records. A total of 515 (7%) inspections with one or more personal airborne chemical substance samples were identified for further study. Inspections by report of a hazard and by targeting were compared for the following: number of inspections, number and percentage of inspections with workers exposed to substances above an agency's permissible exposure limit, types of industries inspected, and number and type of chemical substances assessed. Report of a hazard inspections documented work sites with worker overexposure at the same rate as agency targeted inspections (approximately 35% of the time), suggesting that complainants and referents are a credible pool of observers capable of directing the agency to airborne chemical substance hazards. Report of a hazard inspections were associated with significantly broader distribution of industries as well as a greater variety of chemical substance exposures than were targeted inspections. Narrative text that described business type and processes inspected was more useful than NAICS codes alone and critical in identifying processes and industries that may be associated with new hazards. Finally, previously identified emerging hazards were found among the report of a hazard data. These findings indicate that surveillance of OSHA inspection data can be a valid tool to identify uncharacterized and emerging health hazards. Additional research is needed to develop criteria for objective review and prioritization of the data for intervention. Federal OSHA and other state

Top five industries resulting in injuries from acute chemical incidents—Hazardous Substance Emergency Events Surveillance, nine states, 1999-2008.

Science.gov (United States)

Anderson, Ayana R; Wu, Jennifer

2015-04-10

Because industries using and/or producing chemicals are located in close proximity to populated areas, U.S. residents are at risk for unintentional chemical exposures. 1999-2008. The Hazardous Substances Emergency Events Surveillance (HSEES) system was operated by the Agency for Toxic Substances and Disease Registry during January 1991-September 2009 to collect data that would enable researchers to describe the public health consequences of chemical releases and to develop activities aimed at reducing the harm from such releases. This report summarizes data for the top five industries resulting in injuries from an acute chemical incident (lasting truck transportation, educational services, chemical manufacturing, utilities, and food manufacturing) accounted for approximately one third of all incidents in which persons were injured as a result of unintentional release of chemicals; the same five industries were responsible for approximately one third of all persons injured as a result of such releases. Acute chemical incidents in these five industries resulted in serious public health implications including the need for evacuations, morbidity, and mortality. PUBLIC HEALTH IMPLICATIONS: Targeting chemical incident prevention and preparedness activities towards these five industries provides an efficient use of resources for reducing chemical exposures. A variety of methods can be used to minimize chemical releases in industries. One example is the Occupational Safety and Health Administration's hierarchy of controls model, which focuses on controlling exposures to occupational hazards. The hierarchy includes elimination, substitution, engineering controls, administrative controls, and use of personal protective equipment.

Contingency plan for the Lawrence Livermore National Laboratory, Site 300, hazardous waste operations

International Nuclear Information System (INIS)

Gonzalez, M.A.

1983-01-01

This contingency plan for hazardous waste release provides guidance for coordinating response efforts. With a goal to minimize hazards to human health and life; and protect livestock, wildlife, the environment, and property in the event of a fire, explosion, or any unplanned release of hazardous substances or mixtures to the air, water, or soil. In this document, hazardous waste includes all waste substances or mixtures that: contain any of the hazardous substances listed in the Resource Conservation and Recovery Act; have the characteristic of being toxic, flammable, reactive, corrosive, an irritant, and/or a strong sensitizer; are radioactive and are used in experiments at Site 300; or could have a significant effect on the environment. This Plan includes an overview of emergency response capabilities; and responsibilities assigned to both LLNL and non-LLNL emergency response personel

The evaluation of an analytical protocol for the determination of substances in waste for hazard classification.

Science.gov (United States)

Hennebert, Pierre; Papin, Arnaud; Padox, Jean-Marie; Hasebrouck, Benoît

2013-07-01

The classification of waste as hazardous could soon be assessed in Europe using largely the hazard properties of its constituents, according to the the Classification, Labelling and Packaging (CLP) regulation. Comprehensive knowledge of the component constituents of a given waste will therefore be necessary. An analytical protocol for determining waste composition is proposed, which includes using inductively coupled plasma (ICP) screening methods to identify major elements and gas chromatography/mass spectrometry (GC-MS) screening techniques to measure organic compounds. The method includes a gross or indicator measure of 'pools' of higher molecular weight organic substances that are taken to be less bioactive and less hazardous, and of unresolved 'mass' during the chromatography of volatile and semi-volatile compounds. The concentration of some elements and specific compounds that are linked to specific hazard properties and are subject to specific regulation (examples include: heavy metals, chromium(VI), cyanides, organo-halogens, and PCBs) are determined by classical quantitative analysis. To check the consistency of the analysis, the sum of the concentrations (including unresolved 'pools') should give a mass balance between 90% and 110%. Thirty-two laboratory samples comprising different industrial wastes (liquids and solids) were tested by two routine service laboratories, to give circa 7000 parameter results. Despite discrepancies in some parameters, a satisfactory sum of estimated or measured concentrations (analytical balance) of 90% was reached for 20 samples (63% of the overall total) during this first test exercise, with identified reasons for most of the unsatisfactory results. Regular use of this protocol (which is now included in the French legislation) has enabled service laboratories to reach a 90% mass balance for nearly all the solid samples tested, and most of liquid samples (difficulties were caused in some samples from polymers in solution and

Dermal uptake of petroleum substances

NARCIS (Netherlands)

Jakasa, Ivone; Kezic, Sanja; Boogaard, Peter J.

2015-01-01

Petroleum products are complex substances comprising varying amounts of linear and branched alkanes, alkenes, cycloalkanes, and aromatics which may penetrate the skin at different rates. For proper interpretation of toxic hazard data, understanding their percutaneous absorption is of paramount

Hazard Communication Standard

International Nuclear Information System (INIS)

Sichak, S.

1991-01-01

The current rate of technological advances has brought with it an overwhelming increase in the usage of chemicals in the workplace and in the home. Coupled to this increase has been a heightened awareness in the potential for acute and chronic injuries attributable to chemical insults. The Hazard Communication Standard has been introduced with the desired goal of reducing workplace exposures to hazardous substances and thereby achieving a corresponding reduction in adverse health effects. It was created and proclaimed by the US Department of Labor and regulated by the Occupational Safety and Health Administration. 1 tab

Robotics and artificial intelligence for hazardous environments

International Nuclear Information System (INIS)

Spelt, P.F.

1993-01-01

In our technological society, hazardous materials including toxic chemicals, flammable, explosive, and radioactive substances, and biological agents, are used and handled routinely. Each year, many workers who handle these substances are accidently contaminated, in some cases resulting in injury, death, or chronic disabilities. If these hazardous materials could be handled remotely, either with a teleoperated robot (operated by a worker in a safe location) or by an autonomous robot, then human suffering and economic costs of accidental exposures could be dramatically reduced. At present, it is still difficult for commercial robotic technology to completely replace humans involved in performing complex work tasks in hazardous environments. The robotics efforts at the Center for Engineering Systems Advanced Research represent a significant effort at contributing to the advancement of robotics for use in hazardous environments. While this effort is very broad-based, ranging from dextrous manipulation to mobility and integrated sensing, the technical portion of this paper will focus on machine learning and the high-level decision making needed for autonomous robotics

Determination of Substances Content of Soil Surface Using Fast Neutron Activation Analysis

International Nuclear Information System (INIS)

Elin Nuraini; Elisabeth; Sunardi

2002-01-01

Determination of substances content of soil surface using neutron activation analysis has been performed. The aim of this research is to determine whether there are any dangerous, hazardous and toxic substances that released from The Research and Development Center for Advanced Technology (RDCAT) as a government institution has possibility in releasing that substances to the environment by surface water, sewage or rain water that give any dangerous the environmental. The fast neutron activation analysis was used to analyze the type and concentration of substances qualitative and quantitatively. The quantitative analysis was performed using relative method. Samples were counted using NaI(TI) detector. The result showed that there are several substances such as Mn-55, Fe-56, P-31, Al-27. Zn,65 and Mg-24. And there are found any hazardous, dangerous and toxic substances in the samples that causing any danger to human and environment. (author)

[Airport security check of medical substances used during patient repatriation].

Science.gov (United States)

Felkai, Péter

2012-09-16

During airport security check of passenger luggage, hazardous items and substances are prohibited to be taken into the restricted safety zone of the airport and the aircraft. Among equipment of the medical staff escorting the patient, there are several devices and materials which are considered hazardous for security reasons. However, medical equipment and substances are indispensable for treating patients during the flight. The aim of the author was to present his experience obtained with the use of an instrument developed for testing liquids, aerosols and gels for security reasons. An instrument based on Raman spectroscopy was used for the identification of medical substances. The results confirmed that the instrument was able to recognize the tested medical substances. The non-destructive testing maintained sample integrity and asepsis. The data indicate that the instrument has a promising utility for the identification of medical substances. It seems important that during repatriation medical substances should be selected not only on the ground of their medical necessity, but their packaging should be also taken into consideration. It is necessary to perform more tests on different medical substances used in emergency care in order to make the database of medical substances stored in the library of instrument more complete.

Preliminary Hazard Classification of the 1714-N, Lead Storage

International Nuclear Information System (INIS)

Kerr, N. R.

1999-01-01

The 1714-N, -NA and -NB is a building segment that was deactivated under the N Area Deactivation Project. During the deactivation the building was designated as an area to store recycled or reused lead products. This document presents the Preliminary Hazard Classification (PHC) for the continued storage of lead products by Bechtel Hanford, Inc. (BHI). Two types of hazardous substances are the focus of this PHC: lead and residual radiological contamination. An evaluation contained in this PHC concludes that there is little risk from the remaining hazardous substances. It was further concluded that standard institutional controls that are implemented under the BHI contract provide adequate protection to people and the environment. No further safety analysis documentation is required for the continued lead storage

Soil contamination in south Backa region of Serbia with dangerous and harmful substances

Directory of Open Access Journals (Sweden)

Maksimović Livija

2012-01-01

Full Text Available Soil samples in disturbed state were taken in order to control fertility and monitor contents of harmful and hazardous substances in Vojvodina soils and possibilities of soil degradation in general. Moderately contaminated soils were selected for examination. Microbial activity in contaminated soil and the impact of harmful and hazardous substances (pesticides on soil microorganisms were observed and most resistant microorganisms were isolated. Vegetation experiments were organized to study the effect of chelating agents EDTA and EDDS on copper adoption and translocation in rapeseed and sunflower. Importance of some ions in the complexation of copper chelators and their undesirable effects on copper uptake were established. Field trials were organized to study the effect of hydrogel on water uptakes by plants, increase in rate and the increase in rate of removal of hazardous and harmful substances from soil solution. At all phases of the project, we monitored the effectiveness of soil bioremediation soils by means of the application of chelating agents, stimulative preparations such as hydrogel and certain microorganisms. It effectiveness was measured in terms of plant growth rate and intensity in removal of hazardous and harmful substances from contaminated soil.

Hazardous air pollutants; Yugai taiki osen busshitsu

Energy Technology Data Exchange (ETDEWEB)

Ogata, A

2000-02-14

Hazardous air pollutants (HAPs) are chemical substances listed up since those have a fear of increasing carcinogenic danger even in a small quantity by a long-term exposure. In Europe and Japan, approximately 200 names of substances are known. Concretely, they are particulate substnaces such as floating dusts, gaseous inorganics such as fluorine compound and chroline gas, volatile organic compounds (VOCs). Among those, especially, 22 substances are cited as those that Japan tackles in priority. HAPs explained in this paper mean mostly VOCs such as benzene, tetrachloroethylene and trichloroethylene among those. (NEDO)

Toxic substances registry system: Index of material safety data sheets

Science.gov (United States)

1993-01-01

The Material Safety Data Sheets (MSDS's) listed in this index reflect product inventories and associated MSDS's which were submitted to the Toxic Substances Registry database maintained by the Base Operations Contractor at the Kennedy Space Center. The purpose of this index is to provide KSC government, contractor, and tenant organizations a means to access information on the hazards associated with these chemicals. The Toxic Substance Registry Service (TSRS) was established to manage information dealing with the storage and use of toxic and otherwise hazardous materials at KSC. As a part of this service, the BOC Environmental Health Services maintains a central repository of MSDS's which were provided to TSRS. The data on the TSRS are obtained from NASA, contractor, and tenant organizations who use or store hazardous materials at KSC. It is the responsibility of these organizations to conduct inventories, obtain MSDS's, distribute Hazard Communication information to their employees, and otherwise implement compliance with appropriate Federal, State, and NASA Hazard Communication and Worker Right-to-Know regulations and policies.

Hazard analysis in uranium hexafluoride production facility

International Nuclear Information System (INIS)

Marin, Maristhela Passoni de Araujo

1999-01-01

The present work provides a method for preliminary hazard analysis of nuclear fuel cycle facilities. The proposed method identify both chemical and radiological hazards, as well as the consequences associated with accident scenarios. To illustrate the application of the method, a uranium hexafluoride production facility was selected. The main hazards are identified and the potential consequences are quantified. It was found that, although the facility handles radioactive material, the main hazards as associated with releases of toxic chemical substances such as hydrogen fluoride, anhydrous ammonia and nitric acid. It was shown that a contention bung can effectively reduce the consequences of atmospheric release of toxic materials. (author)

A re-evaluation of PETROTOX for predicting acute and chronic toxicity of petroleum substances.

Science.gov (United States)

Redman, Aaron D; Parkerton, Thomas F; Leon Paumen, Miriam; Butler, Josh D; Letinski, Daniel J; den Haan, Klass

2017-08-01

The PETROTOX model was developed to perform aquatic hazard assessment of petroleum substances based on substance composition. The model relies on the hydrocarbon block method, which is widely used for conducting petroleum substance risk assessments providing further justification for evaluating model performance. Previous work described this model and provided a preliminary calibration and validation using acute toxicity data for limited petroleum substance. The objective of the present study was to re-evaluate PETROTOX using expanded data covering both acute and chronic toxicity endpoints on invertebrates, algae, and fish for a wider range of petroleum substances. The results indicated that recalibration of 2 model parameters was required, namely, the algal critical target lipid body burden and the log octanol-water partition coefficient (K OW ) limit, used to account for reduced bioavailability of hydrophobic constituents. Acute predictions from the updated model were compared with observed toxicity data and found to generally be within a factor of 3 for algae and invertebrates but overestimated fish toxicity. Chronic predictions were generally within a factor of 5 of empirical data. Furthermore, PETROTOX predicted acute and chronic hazard classifications that were consistent or conservative in 93 and 84% of comparisons, respectively. The PETROTOX model is considered suitable for the purpose of characterizing petroleum substance hazard in substance classification and risk assessments. Environ Toxicol Chem 2017;36:2245-2252. © 2017 SETAC. © 2017 SETAC.

Transportation training: Focusing on movement of hazardous substances and wastes

International Nuclear Information System (INIS)

Jones, E.; Moreland, W.M.

1988-01-01

Over the past 25 years extensive federal legislation involving the handling and transport of hazardous materials/waste has been passed that has resulted in numerous overlapping regulations administered and enforced by different federal agencies. The handling and transport of hazardous materials/waste involves a significant number of workers who are subject to a varying degree of risk should an accident occur during handling or transport. Effective transportation training can help workers address these risks and mitigate them, and at the same time enable ORNL to comply with the federal regulations concerning the transport of hazardous materials/waste. This presentation will outline how the Environmental and Health Protection Division's Technical Resources and Training Program at the Oak Ridge National Laboratory, working with transportation and waste disposal personnel, are developing and implementing a comprehensive transportation safety training program to meet the needs of our workers while satisfying appropriate federal regulations. 8 refs., 5 figs., 3 tabs

Waste paper for recycling: Overview and identification of potentially critical substances

DEFF Research Database (Denmark)

Pivnenko, Kostyantyn; Eriksson, Eva; Astrup, Thomas Fruergaard

2015-01-01

by nearly 20% within the last decade or so, reaching a level of almost 72% in 2012. With increasing recycling rates, lower quality paper fractions may be included. This may potentially lead to accumulation or un-intended spreading of chemical substances contained in paper, e.g. by introducing chemicals...... contained in waste paper into the recycling loop. This study provides an overview of chemicals potentially present in paper and applies a sequential hazard screening procedure based on the intrinsic hazard, physical-chemical and biodegradability characteristics of the substances. Based on the results, 51...

78 FR 60755 - Hazardous Materials: Enhanced Enforcement Procedures-Resumption of Transportation

Science.gov (United States)

2013-10-02

... material,'' we envisioned etiological agents, such as biological products, infectious substances, medical... accidents or incidents involving the transportation of hazardous material. In order to achieve a uniform... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration 49 CFR Part...

Hazardous materials management and compliance training

International Nuclear Information System (INIS)

Dalton, T.F.

1991-01-01

OSHA training for hazardous waste site workers is required by the Superfund Amendments and Reauthorization Act of 1986 (SARA). In December 1986, a series of regulations was promulgated by OSHA on an interim basis calling for the training of workers engaged in hazardous waste operations. Subsequent to these interim regulations, final rules were promulgated and these final rules on hazardous waste operations and emergency response became effective on March 6, 1990. OSHA has conducted hearings on the accreditation of training programs. OSHA would like to follow the accreditation process under the AHERA regulations for asbestos, in which the model plan for accreditation of asbestos abatement training was included in Section 206 of Title 11 of the Toxic Substance Control Act (TSCA). OSHA proposed on January 26, 1990, to perform the accreditation of training programs for hazardous waste operations and that proposal suggested that they follow the model plan similar to the one used for AHERA. They did not propose to accredited training programs for workers engaged in emergency response. These new regulations pose a significant problem to the various contractors and emergency responders who deal with hazardous materials spill response, cleanup and site remediation since these programs have expanded so quickly that many people are not familiar with what particular segment of the training they are required to have and whether or not programs that have yet to be accredited are satisfactory for this type of training. Title III of SARA stipulates a training program for first responders which includes local emergency response organizations such as firemen and policemen. The purpose of this paper is to discuss the needs of workers at hazardous waste site remediation projects and workers who are dealing with hazardous substances, spill response and cleanup

A Marine Hazardous Substances Data System. Volume 2.

Science.gov (United States)

1985-12-01

HAZARDOUS CARGOS (CONT’D) *20-DEC-85 CHEMICAL NAIIE CHRIS CFR OTHER TLV-TWA SEG CODE ROUTE PPM NO. WAX : CANDELILLA D 684 WAX . CARNAUBA WCA D 685 WAX ...50 693 * WAX : PARAFFIN IJPF D 2 MG/M3 696 MXYLENE XLM D 100 693 O-XYLENE XLO D 100 694 P-XYLENE XLP D 100 695 ZINC DIALKYLDITHIOPHOSPHATE ZDP D 10

An OSHA based approach to safety analysis for nonradiological hazardous materials

International Nuclear Information System (INIS)

Yurconic, M.

1992-08-01

The PNL method for chemical hazard classification defines major hazards by means of a list of hazardous substances (or chemical groups) with associated trigger quantities. In addition, the functional characteristics of the facility being classified is also be factored into the classification. In this way, installations defined as major hazard will only be those which have the potential for causing very serious incidents both on and off site. Because of the diversity of operations involving chemicals, it may not be possible to restrict major hazard facilities to certain types of operations. However, this hazard classification method recognizes that in the industrial sector major hazards are most commonly associated with activities involving very large quantities of chemicals and inherently energetic processes. These include operations like petrochemical plants, chemical production, LPG storage, explosives manufacturing, and facilities which use chlorine, ammonia, or other highly toxic gases in bulk quantities. The basis for this methodology is derived from concepts used by OSHA in its proposed chemical process safety standard, the Dow Fire and Explosion Index Hazard Classification Guide, and the International Labor Office's program on chemical safety. For the purpose of identifying major hazard facilities, this method uses two sorting criteria, (1) facility function and processes and (2) quantity of substances to identify facilities requiringclassification. Then, a measure of chemical energy potential (material factor) is used to identify high hazard class facilities

Hazard reduction for the application of titania nanoparticles in environmental technology

NARCIS (Netherlands)

Reijnders, L.

2008-01-01

Photocatalytically active titania (TiO2) nanoparticles are applied, and considered for application, in the degradation of hazardous substances. However, these nanoparticles are also hazardous by themselves. High efficiency immobilization of TiO2 nanoparticles on large inorganic supports that are not

APROBA-Plus: A probabilistic tool to evaluate and express uncertainty in hazard characterization and exposure assessment of substances.

Science.gov (United States)

Bokkers, Bas G H; Mengelers, Marcel J; Bakker, Martine I; Chiu, Weihsueh A; Slob, Wout

2017-12-01

To facilitate the application of probabilistic risk assessment, the WHO released the APROBA tool. This tool applies lognormal uncertainty distributions to the different aspects of the hazard characterization, resulting in a probabilistic health-based guidance value. The current paper describes an extension, APROBA-Plus, which combines the output from the probabilistic hazard characterization with the probabilistic exposure to rapidly characterize risk and its uncertainty. The uncertainty in exposure is graphically compared with the uncertainty in the target human dose, i.e. the dose that complies with the specified protection goals. APROBA-Plus is applied to several case studies, resulting in distinct outcomes and illustrating that APROBA-Plus could serve as a standard extension of routine risk assessments. By visualizing the uncertainties, APROBA-Plus provides a more transparent and informative outcome than the more usual deterministic approaches, so that risk managers can make better informed decisions. For example, APROBA-Plus can help in deciding whether risk-reducing measures are warranted or that a refined risk assessment would first be needed. If the latter, the tool can be used to prioritize possible refinements. APROBA-Plus may also be used to rank substances into different risk categories, based on potential health risks without being compromised by different levels of conservatism that may be associated with point estimates of risk. Copyright © 2017 Elsevier Ltd. All rights reserved.

Radioactive hazards

International Nuclear Information System (INIS)

Gill, J.R.

1980-01-01

The use of radioactive substances in hospital laboratories is discussed and the attendant hazards and necessary precautions examined. The new legislation under the Health and Safety at Work Act which, it is proposed, will replace existing legal requirements in the field of health and safety at work by a system of regulations and approved codes of practice designed to maintain or improve the standards of health, safety and welfare already established, is considered with particular reference to protection against ionising radiations. (UK)

77 FR 3223 - National Emissions Standards for Hazardous Air Pollutants: Mineral Wool Production and Wool...

Science.gov (United States)

2012-01-23

... Emission Standards for Hazardous Air Pollutants: Mineral Wool Production Risk and Technology Review..., Administrative practice and procedure, Air pollution control, Hazardous substances, Intergovernmental relations... National Emissions Standards for Hazardous Air Pollutants: Mineral Wool Production and Wool Fiberglass...

The hazard communication of fragrance allergens must be improved.

Science.gov (United States)

Klaschka, Ursula

2013-07-01

Contact allergy is a global health problem that could be alleviated considerably if the general public could reduce contact to sensitizers. Efficient hazard communication would be a valuable instrument to achieve this. What do current regulations concerning fragrance sensitizers in cosmetic products in Europe contribute? For example, there are bans and restrictions according to the Cosmetic Regulation, there is the "26 allergens rule" that requires that the names of some allergenic fragrance ingredients are listed on the containers, there is labeling and classification of hazardous products according to Regulation 1272/2008, and there is the regulation concerning the registration, evaluation, authorization and restriction of chemicals (REACH). Do these regulations increase consumer protection by suitable hazard communication instruments? Four main problems were identified. First, according to the 26 allergens rule, consumers carry a very large part of the responsibility for risk reduction management. They need to be capable and motivated to recognize the names of strong allergens listed in the ingredient list and decide for themselves whether they want to run the risk or not, provided that they are aware of their responsibility. Second, cosmetic products do not need to be classified and labeled like other consumer goods, according to the European Commission Regulation 1272/2008, if they contain hazardous substances. Third, some pictograms for hazardous substances, for example, the exclamation mark for sensitizers, are not well understood by the majority of the general public. Fourth, very often, the design of cosmetic containers implies health and well being, even if the respective products contain sensitizers or other hazardous substances. Against this background, the following improvements are proposed: 1) the 26 allergens rule needs revision, 2) the exception for cosmetic products from labeling and classification should be abolished, 3) a new self

40 CFR 280.42 - Requirements for hazardous substance UST systems.

Science.gov (United States)

2010-07-01

... automatic line leak detector in accordance with § 280.44(a). (5) Other methods of release detection may be...-water intrusion with the ability to contain or detect a release of regulated substances; and (iii...

Journal of NIRE, Vol. 5, No. 1, January 1996. Special issue: Behavior in the environment and countermeasure technology of hazardous chemicals

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-01-01

Contents: Technique for Management of Hazardous Chemical Substances --Risk Assessment; Behaviors of Chemicals in the Aquatic Environment; Numerical Model of Chemical Fate in an Environment; Source Characterization and Chemical Processes of Volatile Organic Compounds in the Atmosphere; Development of Sensor for Hazardous Substances; Removal of Chemical Substances from the Atmosphere by Photocatalysis; Microbial Degradation of Organic Xenobiotics in Environment.

Hazard ranking systems for chemical wastes and chemical waste sites

International Nuclear Information System (INIS)

Waters, R.D.; Parker, F.L.; Crutcher, M.R.

1991-01-01

Hazardous materials and substances have always existed in the environment. Mankind has evolved to live with some degree of exposure to toxic materials. Until recently the risk has been from natural toxins or natural background radiation. While rapid technological advances over the past few decades have improved the lifestyle of our society, they have also dramatically increased the availability, volume and types of synthetic and natural hazardous materials. Many of their effects are as yet uncertain. Products and manufacturing by-products that no longer serve a useful purpose are deemed wastes. For some waste products land disposal will always be their ultimate fate. Hazardous substances are often included in the waste products. One needs to classify wastes by degree of hazard (risk). Risk (degree of probability of loss) is usually defined for risk assessment as probability of an occurrence times the consequences of the occurrence. Perhaps even more important than the definition of risk is the choice of a risk management strategy. The choice of strategy will be strongly influenced by the decision criteria used. Those decision criteria could be utility (the greatest happiness of the greatest number), rights or technology based or some combination of the three. It is necessary to make such choices about the definition of risks and criteria for management. It is clear that these are social (i.e., political) and value choices and science has little to say on this matter. This is another example of what Alvin Weinberg has named Transcience where the subject matter is scientific and technical but the choices are social, political and moral. This paper shall deal only with the scientific and technical aspects of the hazardous waste problem to create a hazardous substances classification system

Self-Medication: potential risks and hazards among pregnant ...

African Journals Online (AJOL)

Self-Medication: potential risks and hazards among pregnant women in Uyo, ... Reasons for using these substances range from protection from witches and ... shows that self-medication is common among pregnant women in our environment.

Waste paper for recycling: Overview and identification of potentially critical substances.

Science.gov (United States)

Pivnenko, Kostyantyn; Eriksson, Eva; Astrup, Thomas F

2015-11-01

Paper product manufacturing involves a variety of chemicals used either directly in paper and pulp production or in the conversion processes (i.e. printing, gluing) that follow. Due to economic and environmental initiatives, paper recycling rates continue to rise. In Europe, recycling has increased by nearly 20% within the last decade or so, reaching a level of almost 72% in 2012. With increasing recycling rates, lower quality paper fractions may be included. This may potentially lead to accumulation or un-intended spreading of chemical substances contained in paper, e.g. by introducing chemicals contained in waste paper into the recycling loop. This study provides an overview of chemicals potentially present in paper and applies a sequential hazard screening procedure based on the intrinsic hazard, physical-chemical and biodegradability characteristics of the substances. Based on the results, 51 substances were identified as potentially critical (selected mineral oils, phthalates, phenols, parabens, as well as other groups of chemicals) in relation to paper recycling. It is recommended that these substances receive more attention in waste paper. Copyright © 2015 Elsevier Ltd. All rights reserved.

Measures of Physical and Mental Independence Among HIV-Positive Individuals: Impact of Substance Use Disorder.

Science.gov (United States)

Christensen, Bianca; Qin, Zijian; Byrd, Desiree A; Yu, Fang; Morgello, Susan; Gelman, Benjamin B; Moore, David J; Grant, Igor; Singer, Elyse J; Fox, Howard S; Baccaglini, Lorena

2017-10-01

With the transition of HIV infection from an acute to a chronic disease after the introduction of antiretroviral medications, there has been an increased focus on long-term neurocognitive and other functional outcomes of HIV patients. Thus, we assessed factors, particularly history of a substance use disorder, associated with time to loss of measures of physical or mental independence among HIV-positive individuals. Data were obtained from the National NeuroAIDS Tissue Consortium. Kaplan-Meier and Cox proportional hazards regression analyses were used to estimate the time since HIV diagnosis to loss of independence, and to identify associated risk factors. HIV-positive participants who self-identified as physically (n = 698) or mentally (n = 616) independent on selected activities of daily living at baseline were eligible for analyses. A history of substance use disorder was associated with a higher hazard of loss of both physical and mental independence [adjusted hazard ratio (HR) = 1.71, 95% confidence interval (95% CI): 1.07-2.78; adjusted HR = 1.67, 95% CI: 1.11-2.52, respectively]. After adjusting for substance use disorder and other covariates, older age at diagnosis and female gender were associated with higher hazards of loss of both physical and mental independence, non-white participants had higher hazards of loss of physical independence, whereas participants with an abnormal neurocognitive diagnosis and fewer years of education had higher hazards of loss of mental independence. In summary, history of substance use disorder was associated with loss of measures of both physical and mental independence. The nature of this link and the means to prevent such loss of independence need further investigation.

The Problems of implementation of the European Union directives for electrical and electronic equipment hazardousness

OpenAIRE

Vaišvila, Anicetas; Vaičikonis, Eduardas

2006-01-01

The problems of implementation of two new EU Directives is discussed in this article. It is so called WEEE (Waste Electrical and Electronic Equipment) and RoHS (Restriction of use of certain Hazardous Substances in electrical and electronic equipment), as well as influence of these directives to quality and environmental management systems. The RoHS directive requires a number of potentially hazardous substances (lead, mercury, cadmium, hexavalent chromium, polybrominated byphenyls (PBB) and ...

Screening for prenatal substance use: development of the Substance Use Risk Profile-Pregnancy scale.

Science.gov (United States)

Yonkers, Kimberly A; Gotman, Nathan; Kershaw, Trace; Forray, Ariadna; Howell, Heather B; Rounsaville, Bruce J

2010-10-01

To report on the development of a questionnaire to screen for hazardous substance use in pregnant women and to compare the performance of the questionnaire with other drug and alcohol measures. Pregnant women were administered a modified TWEAK (Tolerance, Worried, Eye-openers, Amnesia, K[C] Cut Down) questionnaire, the 4Ps Plus questionnaire, items from the Addiction Severity Index, and two questions about domestic violence (N=2,684). The sample was divided into "training" (n=1,610) and "validation" (n=1,074) subsamples. We applied recursive partitioning class analysis to the responses from individuals in the training subsample that resulted in a three-item Substance Use Risk Profile-Pregnancy scale. We examined sensitivity, specificity, and the fit of logistic regression models in the validation subsample to compare the performance of the Substance Use Risk Profile-Pregnancy scale with the modified TWEAK and various scoring algorithms of the 4Ps. The Substance Use Risk Profile-Pregnancy scale is comprised of three informative questions that can be scored for high- or low-risk populations. The Substance Use Risk Profile-Pregnancy scale algorithm for low-risk populations was mostly highly predictive of substance use in the validation subsample (Akaike's Information Criterion=579.75, Nagelkerke R=0.27) with high sensitivity (91%) and adequate specificity (67%). The high-risk algorithm had lower sensitivity (57%) but higher specificity (88%). The Substance Use Risk Profile-Pregnancy scale is simple and flexible with good sensitivity and specificity. The Substance Use Risk Profile-Pregnancy scale can potentially detect a range of substances that may be abused. Clinicians need to further assess women with a positive screen to identify those who require treatment for alcohol or illicit substance use in pregnancy. III.

KNOWLEDGE DATABASE ON CHEMICAL AND AEROSOL HAZARDS CHEMPYŁ AVAILABLE IN CIOP-PIB PORTAL

Directory of Open Access Journals (Sweden)

Elżbieta Dobrzyńska

2016-12-01

Full Text Available CHEMPYŁ database, which is available on the website of the Central Institute for Labour Protection – National Research Institute, is a source of information for employers, employees and specialists of health and safety in the field of chemical and aerosol hazards at the workplace. The most useful materials in this field, collected in one place in the database are aimed to help in the efficient management of occupational risks associated with the presence of hazardous chemical substances and its mixtures in the working environment. The online CHEMPYŁ database contains sets of definitions, legal acts, database of hazardous chemicals and dusts, as well as the measurement results in form of sixteen separate sections and subsections. The database of measurement results is a collection of practical information on exposure to harmful chemical substances, the results of their qualitative and quantitative measurements in air at the exemplary workplaces or exemplary technological processes from various economy sectors and occupational risk assessment connected with it. The database on hazardous chemicals covers over five hundred and sixty substances, mainly with fixed values of maximum admissible concentrations in Poland, but also more than a thousand substances classified as carcinogenic and mutagenic according to the CLP Regulation, and this material is continuously expanded. Extensive materials are collected in the sections on assessment of occupational exposure to chemicals and dust, as well as risk assessment associated with their use and/or presence at the workplace. Apart from the materials on risk assessment in inhalation and dermal exposure or risk of explosion and fire, data were complemented with non-measurement methods for assessing exposure and occupational risk for carcinogenic and mutagenic substances, and methods to assess the risks associated with chemical substances of nanometric dimensions. Forum, which was created in 2015, allows

Industrial ecology: Environmental chemistry and hazardous waste

Energy Technology Data Exchange (ETDEWEB)

Manahan, S.E. [Univ. of Missouri, Columbia, MO (United States). Dept. of Chemistry

1999-01-01

Industrial ecology may be a relatively new concept -- yet it`s already proven instrumental for solving a wide variety of problems involving pollution and hazardous waste, especially where available material resources have been limited. By treating industrial systems in a manner that parallels ecological systems in nature, industrial ecology provides a substantial addition to the technologies of environmental chemistry. Stanley E. Manahan, bestselling author of many environmental chemistry books for Lewis Publishers, now examines Industrial Ecology: Environmental Chemistry and Hazardous Waste. His study of this innovative technology uses an overall framework of industrial ecology to cover hazardous wastes from an environmental chemistry perspective. Chapters one to seven focus on how industrial ecology relates to environmental science and technology, with consideration of the anthrosphere as one of five major environmental spheres. Subsequent chapters deal specifically with hazardous substances and hazardous waste, as they relate to industrial ecology and environmental chemistry.

The underground diposal of hazardous wastes - necessity, possibilities and limitations

International Nuclear Information System (INIS)

Herrmann, A.G.; Brumsack, H.J.; Heinrichs, H.

1985-01-01

The natural geochemical cycles of many elements in the atmosphere, hydrosphere, and pedosphere have been changed during the past decades by anthropogenic activities. To put a stop to this development, a drastic reduction of the uncontrolled dispersal of potentially hazardous substances into our environment is necessary, compelling the need for the safe disposal of radioactive and nonradioactive hazardous wastes far away from the biosphere. The amount of potentially hazardous waste produced annually in West Germany is larger by a factor of at least 20 than the volume of hazardous material for which suitable underground disposal sites are planned and available at present. (orig.)

Development of tools for integrated monitoring and assessment of hazardous substances and their biological effects in the Baltic Sea.

Science.gov (United States)

Lehtonen, Kari K; Sundelin, Brita; Lang, Thomas; Strand, Jakob

2014-02-01

The need to develop biological effects monitoring to facilitate a reliable assessment of hazardous substances has been emphasized in the Baltic Sea Action Plan of the Helsinki Commission. An integrated chemical-biological approach is vitally important for the understanding and proper assessment of anthropogenic pressures and their effects on the Baltic Sea. Such an approach is also necessary for prudent management aiming at safeguarding the sustainable use of ecosystem goods and Services. The BEAST project (Biological Effects of Anthropogenic Chemical Stress: Tools for the Assessment of Ecosystem Health) set out to address this topic within the BONUS Programme. BEAST generated a large amount of quality-assured data on several biological effects parameters (biomarkers) in various marine species in different sub-regions of the Baltic Sea. New indicators (biological response measurement methods) and management tools (integrated indices) with regard to the integrated monitoring approach were suggested.

Experiences from the exercise ''MERLIN'' for the detection of radioactive substances with the participation of special-purpose vehicles

International Nuclear Information System (INIS)

Griesbach, M.

2009-01-01

Experiences of an exercise with hazardous goods, in particular with radioactive substances (measurements and taking environmental samples) are described. Several special-purpose vehicles with equipment and specially trained crews were used together with radiation protection experts according to the concept of Hesse. It has been the greatest exercise in Hesse with regard to hazardous goods and in particular with regard to ''incidents with radioactive substances''. (orig.)

Household hazardous waste

DEFF Research Database (Denmark)

Fjelsted, Lotte; Christensen, Thomas Højlund

2007-01-01

.) comprised 15-25% and foreign items comprised 10-20%. Water-based paint was the dominant part of the paint waste. The chemical composition of the paint waste and the paint-like waste was characterized by an analysis of 27 substances in seven waste fractions. The content of critical substances was tow......'Paint waste', a part of the 'household hazardous waste', amounting to approximately 5 tonnes was collected from recycling stations in two Danish cities. Sorting and analyses of the waste showed paint waste comprised approximately 65% of the mass, paint-like waste (cleaners, fillers, etc...... and the paint waste was less contaminated with heavy metals than was the ordinary household waste. This may suggest that households no longer need to source-segregate their paint if the household waste is incinerated, since the presence of a small quantity of solvent-based paint will not be harmful when...

40 CFR 721.72 - Hazard communication program.

Science.gov (United States)

2010-07-01

..., processed, or used in the employer's workplace, the employer must add the new information to the MSDS before... implement a written hazard communication program for the substance in each workplace. The written program... the workplace or for individual work areas. (2) The methods the employer will use to inform employees...

Hazardous and Noxious Substances (HNS) in the marine environment: prioritizing HNS that pose major risk in a European context.

Science.gov (United States)

Neuparth, T; Moreira, S; Santos, M M; Reis-Henriques, M A

2011-01-01

Increases in the maritime transportation of Hazardous and Noxious Substances (HNS), alongside the need for an effective response to HNS spills have led environmental managers and the scientific community to focus attention on HNS spill preparedness and responsiveness. In the context of the ARCOPOL project, a weight-of-evidence approach was developed aimed at prioritizing HNS that pose major environmental risks to European waters. This approach takes into consideration the occurrence probability of HNS spills in European Atlantic waters and the severity of exposure associated with their physico-chemical properties and toxicity to marine organisms. Additionally, a screening analysis of the toxicological information available for the prioritization of HNS was performed. Here we discuss the need for a prioritization methodology to select HNS that are likely to cause severe marine environmental effects as an essential step towards the establishment of a more effective preparedness and response to HNS incidents. Copyright © 2010 Elsevier Ltd. All rights reserved.

Risk factors for hazardous events in olfactory-impaired patients.

Science.gov (United States)

Pence, Taylor S; Reiter, Evan R; DiNardo, Laurence J; Costanzo, Richard M

2014-10-01

Normal olfaction provides essential cues to allow early detection and avoidance of potentially hazardous situations. Thus, patients with impaired olfaction may be at increased risk of experiencing certain hazardous events such as cooking or house fires, delayed detection of gas leaks, and exposure to or ingestion of toxic substances. To identify risk factors and potential trends over time in olfactory-related hazardous events in patients with impaired olfactory function. Retrospective cohort study of 1047 patients presenting to a university smell and taste clinic between 1983 and 2013. A total of 704 patients had both clinical olfactory testing and a hazard interview and were studied. On the basis of olfactory function testing results, patients were categorized as normosmic (n = 161), mildly hyposmic (n = 99), moderately hyposmic (n = 93), severely hyposmic (n = 142), and anosmic (n = 209). Patient evaluation including interview, examination, and olfactory testing. Incidence of specific olfaction-related hazardous events (ie, burning pots and/or pans, starting a fire while cooking, inability to detect gas leaks, inability to detect smoke, and ingestion of toxic substances or spoiled foods) by degree of olfactory impairment. The incidence of having experienced any hazardous event progressively increased with degree of impairment: normosmic (18.0%), mildly hyposmic (22.2%), moderately hyposmic (31.2%), severely hyposmic (32.4%), and anosmic (39.2%). Over 3 decades there was no significant change in the overall incidence of hazardous events. Analysis of demographic data (age, sex, race, smoking status, and etiology) revealed significant differences in the incidence of hazardous events based on age (among 397 patients hazardous event, vs 31 of 146 patients ≥65 years [21.3%]; P hazardous event, vs 73 of 265 men [27.6%]; P = .009), and race (among 98 African Americans, 41 [41.8%] with hazardous event, vs 134 of 434 whites [30.9%]; P = .04

Chemical dependency: An occupational hazard in the field of anaesthesia

International Nuclear Information System (INIS)

Ismail, S.

2010-01-01

The medical personnel are vulnerable to substance abuse and dependence due to ready access to substance of abuse. Addiction is considered as an occupational hazard for those involved in the practice of anaesthesia for the same reason. Substance abuse is defined as a psychosocial biogenetic disease, which results from dynamic interplay between a susceptible host and favourable environment. According to the fifth and the last National Survey on Drug Abuse (NSDA) in 1993 by Pakistan Narcotic Control, there are nearly three million drug dependants Review Article Chemical dependency: An occupational hazard in the field of anaesthesia Samina Ismail Department of Anaesthesia, Aga Khan University Hospital, Karachi. in Pakistan, but no data is available to determine the prevalence among medical or anaesthesia personnel. In order to handle the rising trend of chemical abuse, we need to have more surveys and studies on this subject, written policy and educational programme in postgraduate training with proper control and frequent checking of narcotic dispensing. Reporting of drug abuse and rehabilitation of affected doctors are areas which need to be worked upon. (author)

Priority ranking of substances hazardous to the aquatic system according to their exposure and effects for 1993/94; Reihung gewaesserrelevanter, gefaehrlicher Stoffe aufgrund ihrer Exposition und Wirkung fuer 1993/94

Energy Technology Data Exchange (ETDEWEB)

Herrchen, M.; Mueller, M.; Storm, U.; Storm, A.

1997-10-01

For the identification of substances occuring in surface waters and being hazardous to the aquatic ecosystem a tiered selection scheme has been developed and applied in a previous project (Application of a selection scheme for the identification of substances hazardous to the acquatic system, No.: 102 04 109). On the first tier, substances occuring in surface waters were identified by comparison with substances in international lists (such as lists I and II of the Directive 76 464 EEC and annex 1A and 1D of the 3. International North Sea Conference). For substances which are detected in monitoring programs but are not listed in the international lists as well as for substances which are detected in monitoring programs but are not listed in the above lists, the second tier was applied. That comprised a substance ranking according to their hazard for aquatic organisms using a scoring system. For the exposure assessment monitored concentrations are used in order to avoid false positive or negative results. For the effect assessment the respective part of the IPS-system (developed within the EU for the ranking of Existing Chemicals) was used. Direct and indirect effects (bioaccumulation) are considered. On the third tier a source identification was performed identifying point and diffuse sources. Within the framework of the actual project an actualisation of the above feasibility study was performed: monitoring data were taken from 1993 and 1994; additionally, data from the North Sea as well as sediment data were considered. The software was improved in order to enable an easy calculation and assessment of the different results (e.g. use of mean or median values as input for the second tier, differentiation according to various streams; consideration of the statement `not detectable`). The software programme also enables a further implementation of actual data in the near future. (orig.) [Deutsch] Zur Identifizierung von gewaesserrelevanten, gefaehrlichen Stoffen wurde

Stimulant ADHD medication and risk for substance abuse.

Science.gov (United States)

Chang, Zheng; Lichtenstein, Paul; Halldner, Linda; D'Onofrio, Brian; Serlachius, Eva; Fazel, Seena; Långström, Niklas; Larsson, Henrik

2014-08-01

There are persistent concerns of long-term effects of stimulant ADHD medication on the development of substance abuse. Using Swedish national registers, we studied all individuals born between 1960 and 1998 and diagnosed with ADHD (26,249 men and 12,504 women). We investigated the association between stimulant ADHD medication in 2006 and substance abuse during 2009. Substance abuse was indexed by substance-related death, crime, or hospital visits. ADHD medication was not associated with increased rate of substance abuse. Actually, the rate during 2009 was 31% lower among those prescribed ADHD medication in 2006, even after controlling for medication in 2009 and other covariates (hazard ratio: 0.69; 95% confidence interval: 0.57-0.84). Also, the longer the duration of medication, the lower the rate of substance abuse. Similar risk reductions were suggested among children and when investigating the association between stimulant ADHD medication and concomitant short-term abuse. We found no indication of increased risks of substance abuse among individuals prescribed stimulant ADHD medication; if anything, the data suggested a long-term protective effect on substance abuse. Although stimulant ADHD medication does not seem to increase the risk for substance abuse, clinicians should remain alert to the potential problem of stimulant misuse and diversion in ADHD patients. © 2013 The Authors. Journal of Child Psychology and Psychiatry © 2013 Association for Child and Adolescent Mental Health.

29 CFR 570.57 - Exposure to radioactive substances and to ionizing radiations (Order 6).

Science.gov (United States)

2010-07-01

... to Their Health or Well-Being § 570.57 Exposure to radioactive substances and to ionizing radiations... radioactive substances and to ionizing radiations are particularly hazardous and detrimental to health for... involves exposure to ionizing radiations in excess of 0.5 rem per year. (b) Definitions. As used in this...

Risk assessment of hazardous waste transport - perspectives of GIS application

International Nuclear Information System (INIS)

Lazar, R.E.; Dumitrescu, M.; Stefanescu, I.

2001-01-01

Due to the increasing public awareness of the potential risks associated with waste transport, the environmental impact assessment of this activity has become an issue of major importance. This paper presents a project proposal, which can establish a national action plan for waste transport evaluation. Such a programme is sustained by the necessity to obtain an adequate method for the rapid and efficient estimation of individual and social risks due to the transport of hazardous substances in Romania. The main objective is to develop regional strategies for risk assessment in comprising: establishing the areas that must be investigated and their particular characteristics; identifying the transport activities in the areas; determining hazards; establishing the analysis criteria and prioritizing the study areas; evaluating continuous emissions; studying major accidents; studying population health; classifying the risks; establishing regional strategies; implementing political and regulatory measures. The project expectation is to provide a decision tool for risk managers and authorities in order to control or limit transportation and the storage of hazardous substances.(author)

Food contamination with environmentally hazardous chemical substances. Kontamination von Lebensmitteln mit Umweltchemikalien

Energy Technology Data Exchange (ETDEWEB)

Petz, M [Wuppertal Univ. (Gesamthochschule) (Germany, F.R.). Fachbereich 9 - Naturwissenschaften 2 - Chemie - Biologie

1990-01-01

The author explains the difference between residues and contaminants in food. Of the contaminants, the heavy metals lead, cadmium and mercury are discussed at length, e.g. their pathway through the food chain and their accumulation in plants, animals, and humans etc. PCB in food and in mother's milk are gone into, as are the consequences of this contamination. Finally, dibenzofuranes and dibenzodioxins are mentioned, again with a view to the contamination of mother's milk. The health hazards from contaminated food is related to the health hazards of malnutrition and overeating. (MG).

Presence of selected priority and personal care substances in an onsite bathroom greywater treatment facility

DEFF Research Database (Denmark)

Eriksson, Eva; Donner, E.; Ledin, Anna

2010-01-01

-out Priority/Priority Hazardous Substances (PS/PHS) is growing, and it is vital to know their sources and flows in order to generate sustainable emission control strategies. The main objective of this study was to quantify the concentrations and loads of PS/PHS and personal care substances in bathroom...

The dilemma in prioritizing chemicals for environmental analysis: known versus unknown hazards.

Science.gov (United States)

Anna, Sobek; Sofia, Bejgarn; Christina, Rudén; Magnus, Breitholtz

2016-08-10

A major challenge for society is to manage the risks posed by the many chemicals continuously emitted to the environment. All chemicals in production and use cannot be monitored and science-based strategies for prioritization are essential. In this study we review available data to investigate which substances are included in environmental monitoring programs and published research studies reporting analyses of chemicals in Baltic Sea fish between 2000 and 2012. Our aim is to contribute to the discussion of priority settings in environmental chemical monitoring and research, which is closely linked to chemical management. In total, 105 different substances or substance groups were analyzed in Baltic Sea fish. Polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans (PCDD/Fs) and polychlorinated biphenyls (PCBs) were the most studied substances or substance groups. The majority, 87%, of all analyses comprised 20% of the substances or substance groups, whereas 46 substance groups (44%) were analyzed only once. Almost three quarters of all analyses regarded a POP-substance (persistent organic pollutant). These results demonstrate that the majority of analyses on environmental contaminants in Baltic Sea fish concern a small number of already regulated chemicals. Legacy pollutants such as POPs pose a high risk to the Baltic Sea due to their hazardous properties. Yet, there may be a risk that prioritizations for chemical analyses are biased based on the knowns of the past. Such biases may lead to society failing in identifying risks posed by yet unknown hazardous chemicals. Alternative and complementary ways to identify priority chemicals are needed. More transparent communication between risk assessments performed as part of the risk assessment process within REACH and monitoring programs, and information on chemicals contained in consumer articles, would offer ways to identify chemicals for environmental analysis.

Food contamination with environmentally hazardous chemical substances. Kontamination von Lebensmitteln mit Umweltchemikalien

Energy Technology Data Exchange (ETDEWEB)

Petz, M. (Wuppertal Univ. (Gesamthochschule) (Germany, F.R.). Fachbereich 9 - Naturwissenschaften 2 - Chemie - Biologie)

1990-01-01

The author explains the difference between residues and contaminants in food. Of the contaminants, the heavy metals lead, cadmium and mercury are discussed at length, e.g. their pathway through the food chain and their accumulation in plants, animals, and humans etc. PCB in food and in mother's milk are gone into, as are the consequences of this contamination. Finally, dibenzofuranes and dibenzodioxins are mentioned, again with a view to the contamination of mother's milk. The health hazards from contaminated food is related to the health hazards of malnutrition and overeating. (MG).

Defining utility trace substance emissions and risks

International Nuclear Information System (INIS)

Torrens, I.M.

1993-01-01

An update is presented on the activities of EPRI and other organizations, including DOE, aimed at improving the quality of available information on utility trace element emissions, control technologies and risks. Because of these efforts, the state of knowledge is advancing rapidly. The 1990 Clean Air Act Amendments aim to reduce emissions of 189 substances that they designate as hazardous air pollutants - commonly called air toxics. The more neutral term open-quotes trace substancesclose quotes is used in this paper, since most are emitted in extremely low concentrations from utility stacks. The degree of toxicity or hazard at these concentrations is subject to considerable uncertainty, and clarifying this is one of the objectives of the work in progress. The most clear and urgent need emanating from the CAAA has been to obtain reliable information on which of the substances on the CAAA list are emitted from different types of power plants - in what amounts, what risks they pose, how much is removed by today's pollution control equipment. EPRI is addressing the issue on several fronts, e.g.; developing a data base and tools that will enable utilities to estimate emissions levels from their power facilities, given the types of fuels burned and plant characteristics; developing a better understanding of how emissions are transported and transformed before they encounter humans and ecological systems; and assessing the risk to public health and the environment posed by utility releases of these substances

75 FR 28227 - National Emission Standards for Hazardous Air Pollutants: Gold Mine Ore Processing and Production...

Science.gov (United States)

2010-05-20

...-AP48 National Emission Standards for Hazardous Air Pollutants: Gold Mine Ore Processing and Production... published a proposed rule for mercury emissions from the gold mine ore processing and production area source... Environmental protection, Air pollution control, Hazardous substances, Incorporations by reference, Reporting...

Differences between men and women in substance use: the role of educational level and employment status.

Science.gov (United States)

Teixidó-Compañó, Ester; Espelt, Albert; Sordo, Luis; Bravo, María J; Sarasa-Renedo, Ana; Indave, B Iciar; Bosque-Prous, Marina; Brugal, M Teresa

To determine differences between men and women in hazardous drinking, heavy cannabis use and hypnosedative use according to educational level and employment status in the economically active population in Spain. Cross-sectional study with data from 2013 Spanish Household Survey on Alcohol and Drugs on individuals aged 25-64 [n=14,113 (women=6,171; men=7,942)]. Dependent variables were hazardous drinking, heavy cannabis use and hypnosedative consumption; the main independent variables were educational level and employment situation. Associations between dependent and independent variables were calculated with Poisson regression models with robust variance. All analyses were stratified by sex. Hazardous drinking and heavy cannabis use were higher in men, while women consumed more hypnosedatives. The lower the educational level, the greater the gender differences in the prevalence of this substances owing to different consumption patterns in men and women. While men with a lower educational level were higher hazardous drinkers [RII=2.57 (95%CI: 1.75-3.78)] and heavy cannabis users [RII=3.03 (95%CI: 1.88-4.89)] compared to higher educational level, in women the prevalence was the same. Women with a lower education level and men with a higher education level had higher hypnosedative consumption. Unemployment was associated with increased heavy cannabis use and hypnosedative use in both women and men and with lower hazardous drinking only in women. There are differences between men and women in the use of psychoactive substances that can be explained by the unequal distribution of substance use in them according to educational level. Unemployment was associated with substance use in both men and women. Copyright © 2017 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.

Expert geographical information system for assessing hazardous materials in aquatic environments

International Nuclear Information System (INIS)

Regens, J.L.; White, L.; Wright, J.D.; Rene, A.; Mielke, H.; Bakeer, R.; Belkhouche, B.; Barber, M.

1993-01-01

Hazardous substances, including radionuclides, heavy metals, chlorinated hydrocarbons, and industrial solvents, pose unique challenges in terms of environmental restoration and waste management, especially in aquatic environments. When stored, used or disposed of improperly, hazardous materials including transuranic wastes, high level wastes, low level wastes, greater than class C wastes, mixed wastes or chemical wastes can contaminate an array of environmental receptors ranging from soils, sediments, groundwater to surface water. Depending on the specific hazardous substance and site attributes, environmental restoration and waste management can be a complex, problematic activity. This is particularly true for the major Defense Programs facilities managed by the Department of Energy (DOE). This research cluster consists of two discrete elements. Project Element No. 1 develops and applies GIS-based approaches to decision support for environmental restoration by delineating potential exposures and health risks at the Rocky Flats Plant and profiling contemporary and historical demographic/land use patterns at Sandia National Laboratories. Project Element No. 2 develops ESS software for surface water and ground water contaminants in the Mississippi River Basin

Use of genetic toxicity data in GHS mutagenicity classification and labeling of substances.

Science.gov (United States)

Ball, Nicholas S; Hollnagel, Heli M

2017-06-01

One of the key outcomes of testing the potential genotoxicity or mutagenicity of a substance is the conclusion on whether the substance should be classified as a germ cell mutagen and the significance of this for other endpoints such as carcinogenicity. The basis for this conclusion are the criteria presented in classification and labelling systems such as the Globally Harmonized System for classification and labeling (GHS). This article reviews the classification criteria for germ cell mutagenicity and carcinogenicity and how they are applied to substances with evidence of mutagenicity. The implications and suitability of such a classification for hazard communication, risk assessment, and risk management are discussed. It is proposed that genotoxicity assessments should not focus on specifically identifying germ cell mutagens, particularly given the challenges associated with communicating this information in a meaningful way. Rather the focus should be on deriving data to characterize the mode of action and for use in the risk assessment of mutagens, which could then feed into a more robust, risk based management of mutagenic substances versus the current more hazard based approaches. Environ. Mol. Mutagen. 58:354-360, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

Soil arsenic surveys of New Orleans: localized hazards in children's play areas.

Science.gov (United States)

Mielke, Howard W; Gonzales, Chris R; Cahn, Elise; Brumfield, Jessica; Powell, Eric T; Mielke, Paul W

2010-10-01

Arsenic (As) ranks first on the 2005 and 2007 hazardous substances priority lists compiled for the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA). This study describes two New Orleans soil As surveys: (1) a survey of composite soil samples from 286 census tracts and (2) a field survey of soil As at 38 play areas associated with the presence of chromated-copper-arsenate (CCA)-treated wood on residential and public properties. The survey of metropolitan New Orleans soils revealed a median As content of 1.5 mg/kg (range New Orleans probably exists in play areas across the nation. These findings support a precautionary program for testing soils and wood for hazardous substances at all play areas intended for children.

A proposal for a test method for assessment of hazard property HP 12 (“Release of an acute toxic gas”) in hazardous waste classification - Experience from 49 waste

OpenAIRE

Hennebert , Pierre; Samaali , Ismahen; Molina , Pauline

2016-01-01

International audience; A stepwise method for assessment of the HP 12 is proposed and tested with 49 waste samples. The hazard property HP 12 is defined as “Release of an acute toxic gas”: waste which releases acute toxic gases (Acute Tox. 1, 2 or 3) in contact with water or an acid. When a waste contains a substance assigned to one of the following supplemental hazards EUH029, EUH031 and EUH032, it shall be classified as hazardous by HP 12 according to test methods or guidelines (EC, 2014a, ...

Civil liability and compensation for damages caused by certain hazardous and noxious substances during their carriage by sea

International Nuclear Information System (INIS)

Bievre, A. de.

1985-01-01

In this paper current international efforts directed at the establishment of a special legal regime for civil liability and compensation for damages caused by hazardous and noxious substances during their transport by sea, specifically chemicals and liquid gas products, are described and analysed. Special attention is given to the way in which concern with the development of an 'environment oriented' regime which provides full recovery for victims in a reliable manner, on the one hand, and, on the other, considerations relating to cost effectiveness complement or conflict with each other. Another important area of investigation concerns the potential role of the marine insurance industry in accident prevention through the provision of incentives for careful (i.e. safe and environmentally sound) behaviour. There is a distinct regulatory trend in favour of strict liability (i.e. liability without fault) and compulsory insurance. There is also a growing perception of the need to depart from the traditional pattern of maritime liability which channels liability automatically to the person exercizing operational control during transport by sea (i.e. the carrier), and to additionally impose liability on those responsible for the risks attached to the inherently harmful characteristics of the cargoes carried. (orig.) [de

Predictors of time to relapse in amphetamine-type substance users in the matrix treatment program in Iran: a Cox proportional hazard model application.

Science.gov (United States)

Moeeni, Maryam; Razaghi, Emran M; Ponnet, Koen; Torabi, Fatemeh; Shafiee, Seyed Ali; Pashaei, Tahereh

2016-07-26

The aim of this study was to determine which predictors influence the risk of relapse among a cohort of amphetamine-type substance (ATS) users in Iran. A Cox proportional hazards model was conducted to determine factors associated with the relapse time in the Matrix treatment program provided by the Iranian National Center of Addiction Studies (INCAS) between March 2010 and October 2011. Participating in more treatment sessions was associated with a lower probability of relapse. On the other hand, patients with less family support, longer dependence on ATS, and those with an experience of casual sex and a history of criminal offenses were more likely to relapse. This study broadens our understanding of factors influencing the risk of relapse in ATS use among an Iranian sample. The findings can guide practitioners during the treatment program.

24 CFR Appendix I to Subpart C of... - Specific Hazardous Substances

Science.gov (United States)

2010-04-01

... Ketone Naptha Pentane Propylene Oxide Toluene Vinyl Acetate Xylene Hazardous Gases Acetaldehyde Butadiene Butane Ethene Ethylene Ethylene Oxide Hydrogen Liquefied Natural Gas (LNG) Liquefied Petroleum Gas (LPG... Commercial/Industrial Facilities,” by Rolf Jensen and Associates, Inc., April 1982) [49 FR 5105, Feb. 10...

[Exposure to hazardous chemical substances in furniture industry].

Science.gov (United States)

Pośniak, Małgorzata; Kowalska, Joanna; Makhniashvili, Ivan

2005-01-01

The aim of the study was to assess the exposure to organic solvents in plants of the furniture industry. Studies were conducted in five furniture plants. Hazardous chemicals present in the air at workposts were determined by capillary gas chromatography with mass spectrometry and flame ionization detection. The analysis of air samples collected at the workposts allowed to identify the following chemicals occurring during varnishing and cleaning of furniture surface elements: acetone, butan-2-one, ethyl, isobutyl and methoxypropyl acetate, 4-methylpentan-2-on, toluene, ethylbenzene and xylenes. Indices characteristic of combined exposure ranged from 0.13 to 1.67 and exceeded the limit value at 21% of workposts. The results of the study indicate that chemicals present at representative workposts during the furniture production are harmful to health of workers, especially those involved in varnishing and cleaning of furniture elements.

16 CFR 1500.85 - Exemptions from classification as banned hazardous substances.

Science.gov (United States)

2010-01-01

... component has no hazards other than being in a self-pressurized container. (8) Model rocket propellant devices designed for use in light-weight, recoverable, and reflyable model rockets, provided such devices... so designed that the main casing or container does not rupture during operation. (10) Solid fuel...

Dermal uptake of petroleum substances.

Science.gov (United States)

Jakasa, Ivone; Kezic, Sanja; Boogaard, Peter J

2015-06-01

Petroleum products are complex substances comprising varying amounts of linear and branched alkanes, alkenes, cycloalkanes, and aromatics which may penetrate the skin at different rates. For proper interpretation of toxic hazard data, understanding their percutaneous absorption is of paramount importance. The extent and significance of dermal absorption of eight petroleum substances, representing different classes of hydrocarbons, was evaluated. Literature data on the steady-state flux and permeability coefficient of these substances were evaluated and compared to those predicted by mathematical models. Reported results spanned over 5-6 orders of magnitude and were largely dependent on experimental conditions in particular on the type of the vehicle used. In general, aromatic hydrocarbons showed higher dermal absorption than more lipophilic aliphatics with similar molecular weight. The results showed high variation and were largely influenced by experimental conditions emphasizing the need of performing the experiments under "in use" scenario. The predictive models overestimated experimental absorption. The overall conclusion is that, based on the observed percutaneous penetration data, dermal exposure to petroleum hydrocarbons, even of aromatics with highest dermal absorption is limited and highly unlikely to be associated with health risks under real use scenarios. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

A methodology for determining environmental threshold quantities for substances covered by CEPA's Environmental Emergency Regulation

International Nuclear Information System (INIS)

Ketcheson, K.; Shrives, J.

2005-01-01

Sections 199 and 200 of the Canadian Environmental Protection Act (CEPA) 1999 oblige persons who own or manage specified toxic and hazardous substances to develop and implement environmental emergency plans. This paper discussed the methodology for determining how a chemical is assessed for recommending an environmental emergency plan. For Section 199, once substances are declared toxic, each chemical is assessed to determine whether it requires a plan or not. For Section 200, any chemical can be added under the E2 regulations, as long as it can be ascertained that the substance is toxic according to the following criteria: it has an immediate or long-term harmful effect on the environment or its biological diversity; it constitutes a danger to the environment on which human life depends; and/or it constitutes a danger in Canada to human life or health. An overview of the risk evaluation framework was provided, including details of the pre-assessment filter. Summaries of trigger criteria were presented, as well as environmental hazard ratings and details of persistence of organic chemicals in the environment and bioaccumulation. Aquatic toxicity and ingestion toxicity details were also provided. Human hazard ratings included carcinogenicity, inhalation toxicity, dermal toxicity, rabbit and rat toxicity and corrosion and skin irritation ratings. Issues concerning vapour cloud explosions were examined. A reactivity table was presented with hazard descriptions. European Union Threshold quantities were examined, as well as a list of comparisons of selected substances of CEPA with the European Union. It was concluded that the Environmental Emergency Branch (EEB) has created environmental thresholds by first examining how other countries have protected the environment. Substance thresholds for the United States have focused on protecting humans, while Europe has established threshold quantities that work for their countries. The EEB has selected classification tables

Substance Use, Mental Health, HIV Testing, and Sexual Risk Behavior Among Men Who Have Sex With Men in the State of Maharashtra, India.

Science.gov (United States)

Wilkerson, J Michael; Di Paola, Angela; Rawat, Shruta; Patankar, Pallav; Rosser, B R Simon; Ekstrand, Maria L

2018-04-01

Among 433 men who have sex with men in Maharashtra, India who completed an online survey, 23% reported hazardous drinking, 12% illicit substance, and 9% polysubstance use. The overall prevalence of depression and intimate partner violence (IPV) were 58% and 56%, respectively. Participants engaging in hazardous drinking had more sexual partners and were less likely to be married to women. Participants reporting illicit substance use or polysubstance use were more likely to have been out, had more sexual partners, or experienced IPV. Those reporting illicit substance use were more likely to engage in condomless anal sex. Based on our findings, we suggest that public health interventions integrate HIV, substance use, and mental health services.

Applicability of Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA) to releases of radioactive substances

International Nuclear Information System (INIS)

Miller, S.R.

1987-01-01

The Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA), commonly called Superfund, provided a $1.6 billion fund (financed by a tax on petrochemical feedstocks and crude oil and by general revenues) for the cleanup of releases of hazardous substances, including source, special nuclear or byproduct material, and other radioactive substances, from mostly inactive facilities. The US Environmental Protection Agency (EPA) is authorized to require private responsible parties to clean up releases of hazardous substances, or EPA, at its option, may undertake the cleanup with monies from the Fund and recover the monies through civil actions brought against responsible parties. CERCLA imposes criminal penalties for noncompliance with its reporting requirements. This paper will overview the key provisions of CERCLA which apply to the cleanup of radioactive materials

Rates and Predictors of Conversion to Schizophrenia or Bipolar Disorder Following Substance-Induced Psychosis.

Science.gov (United States)

Starzer, Marie Stefanie Kejser; Nordentoft, Merete; Hjorthøj, Carsten

2018-04-01

The authors investigated the rates of conversion to schizophrenia and bipolar disorder after a substance-induced psychosis, as well as risk factors for conversion. All patient information was extracted from the Danish Civil Registration System and the Psychiatric Central Research Register. The study population included all persons who received a diagnosis of substance-induced psychosis between 1994 and 2014 (N=6,788); patients were followed until first occurrence of schizophrenia or bipolar disorder or until death, emigration, or August 2014. The Kaplan-Meier method was used to obtain cumulative probabilities for the conversion from a substance-induced psychosis to schizophrenia or bipolar disorder. Cox proportional hazards regression models were used to calculate hazard ratios for all covariates. Overall, 32.2% (95% CI=29.7-34.9) of patients with a substance-induced psychosis converted to either bipolar or schizophrenia-spectrum disorders. The highest conversion rate was found for cannabis-induced psychosis, with 47.4% (95% CI=42.7-52.3) converting to either schizophrenia or bipolar disorder. Young age was associated with a higher risk of converting to schizophrenia. Self-harm after a substance-induced psychosis was significantly linked to a higher risk of converting to both schizophrenia and bipolar disorder. Half the cases of conversion to schizophrenia occurred within 3.1 years after a substance-induced psychosis, and half the cases of conversion to bipolar disorder occurred within 4.4 years. Substance-induced psychosis is strongly associated with the development of severe mental illness, and a long follow-up period is needed to identify the majority of cases.

Water management in cities of the future using emission control strategies for priority hazardous substances.

Science.gov (United States)

Eriksson, E; Revitt, D M; Ledin, A; Lundy, L; Holten Lützhøft, H C; Wickman, T; Mikkelsen, P S

2011-01-01

Cities of the future face challenges with respect to the quantity and quality of water resources, and multiple managerial options need to be considered in order to safeguard urban surface water quality. In a recently completed project on 'Source control options for reducing emissions of Priority Pollutants' (ScorePP), seven emission control strategies (ECSs) were developed and tested within a semi-hypothetical case city (SHCC) to evaluate their potential to reduce the emission of selected European priority hazardous substances (PHSs) to surface waters. The ECSs included (1) business-as-usual, (2) full implementation of relevant European (EU) directives, (3) ECS2 in combination with voluntary options for household, municipalities and industry, (4) ECS2 combined with industrial treatment and best available technologies (BAT), (5) ECS2 in combination with stormwater and combined sewer overflow treatment, (6) ECS2 in combination with advanced wastewater treatment, and (7) combinations of ECS3-6. The SHCC approach was chosen to facilitate transparency, to allow compensating for data gaps and to decrease the level of uncertainty in the results. The selected PHSs: cadmium (Cd), hexachlorobenzene (HCB), nonylphenol (NP) and pentabromodiphenyl ether (PBDE) differ in their uses and environmental fate and therefore accumulate in surface waters to differing extents in response to the application of alternative ECS. To achieve the required reduction in PHS levels in urban waters the full implementation of existing EU regulation is prioritised and feasible combinations of managerial and technological options (source control and treatment) can be highly relevant for mitigating releases.

Development of neutron interrogation techniques for detection of hazardous substances in containers port

International Nuclear Information System (INIS)

D’Amico, N. M. B; Mayer, R.E; Tartaglione, A.

2013-01-01

This work is aimed at contributing to the effort of nations seeking to control international borders movement of dangerous chemical substances and nuclear material, in accordance with a multitude of agreements signed to that purpose. At this stage, we try to identify the signature of pure substances: chlorine (Cl), nitrogen (N), chromium (Cr), mercury (Hg), cadmium (Cd), uranium (U) y arsenic (As) and, later, to detect their presence in simulated large cargo containers. The technique employed in previous and in current work, consists in the detection of prompt and early decay gammas induced by incident thermal neutrons or fast neutrons thermalized in the cargo array. Uranium has also been detected through the counting of fast neutrons originated in induced fissions. (author)

RIVM ZZS-2-BIO project : the biobased replacement potential of hazardous substances

NARCIS (Netherlands)

Es, van D.S.

2014-01-01

A quick scan of the ZZS (zeer zorgwekkende stoffen) list of 371 substances of very high concern shows that there is significant potential in biobased replacement of part of the list. It is shown that in many cases easily implementable biobased alternatives are already available or in advanced stages

Multivariate Models for Prediction of Human Skin Sensitization Hazard

Science.gov (United States)

Strickland, Judy; Zang, Qingda; Paris, Michael; Lehmann, David M.; Allen, David; Choksi, Neepa; Matheson, Joanna; Jacobs, Abigail; Casey, Warren; Kleinstreuer, Nicole

2016-01-01

One of ICCVAM’s top priorities is the development and evaluation of non-animal approaches to identify potential skin sensitizers. The complexity of biological events necessary to produce skin sensitization suggests that no single alternative method will replace the currently accepted animal tests. ICCVAM is evaluating an integrated approach to testing and assessment based on the adverse outcome pathway for skin sensitization that uses machine learning approaches to predict human skin sensitization hazard. We combined data from three in chemico or in vitro assays—the direct peptide reactivity assay (DPRA), human cell line activation test (h-CLAT), and KeratinoSens™ assay—six physicochemical properties, and an in silico read-across prediction of skin sensitization hazard into 12 variable groups. The variable groups were evaluated using two machine learning approaches, logistic regression (LR) and support vector machine (SVM), to predict human skin sensitization hazard. Models were trained on 72 substances and tested on an external set of 24 substances. The six models (three LR and three SVM) with the highest accuracy (92%) used: (1) DPRA, h-CLAT, and read-across; (2) DPRA, h-CLAT, read-across, and KeratinoSens; or (3) DPRA, h-CLAT, read-across, KeratinoSens, and log P. The models performed better at predicting human skin sensitization hazard than the murine local lymph node assay (accuracy = 88%), any of the alternative methods alone (accuracy = 63–79%), or test batteries combining data from the individual methods (accuracy = 75%). These results suggest that computational methods are promising tools to effectively identify potential human skin sensitizers without animal testing. PMID:27480324

An approach to quantitate and control the mutagenic hazards of environmental chemical and radioactive pollutants

International Nuclear Information System (INIS)

Murthy, M.S.S.

1977-01-01

Human population, both at the occupational and non-occupational levels, is exposed to the environment polluted by man-made chemicals and radiation sources. The parameters required for quantitating mutagenic hazards of any agent are listed and it has been pointed out that though sufficient information of this nature is available in the case of radiations, it is almost impossible to collect similar information for chemical substances due to their number running into astronomical figures. A short-cut approach, therefore, is suggested to quantitate and control the mutagenic hazards of these pollutants. It is to express the mutagenic hazards of a chemical substance in terms of equivalent radiation units. The unit proposed for this purpose is called as Rem-Equivalent Chemical (REC). Total mutagenic burden to the society should take account of exposure from both chemicals and radiations. Advantages and limitation of this approach are discussed. (M.G.B.)

A proposal for a test method for assessment of hazard property HP 12 ("Release of an acute toxic gas") in hazardous waste classification - Experience from 49 waste.

Science.gov (United States)

Hennebert, Pierre; Samaali, Ismahen; Molina, Pauline

2016-12-01

A stepwise method for assessment of the HP 12 is proposed and tested with 49 waste samples. The hazard property HP 12 is defined as "Release of an acute toxic gas": waste which releases acute toxic gases (Acute Tox. 1, 2 or 3) in contact with water or an acid. When a waste contains a substance assigned to one of the following supplemental hazards EUH029, EUH031 and EUH032, it shall be classified as hazardous by HP 12 according to test methods or guidelines (EC, 2014a, 2014b). When the substances with the cited hazard statement codes react with water or an acid, they can release HCl, Cl 2 , HF, HCN, PH 3 , H 2 S, SO 2 (and two other gases very unlikely to be emitted, hydrazoic acid HN 3 and selenium oxide SeO 2 - a solid with low vapor pressure). Hence, a method is proposed:For a set of 49 waste, water addition did not produce gas. Nearly all the solid waste produced a gas in contact with hydrochloric acid in 5 min in an automated calcimeter with a volume >0.1L of gas per kg of waste. Since a plateau of pressure is reached only for half of the samples in 5 min, 6 h trial with calorimetric bombs or glass flasks were done and confirmed the results. Identification of the gases by portable probes showed that most of the tested samples emit mainly CO 2 . Toxic gases are emitted by four waste: metallic dust from the aluminum industry (CO), two air pollution control residue of industrial waste incinerator (H 2 S) and a halogenated solvent (organic volatile(s) compound(s)). HF has not been measured in these trials started before the present definition of HP 12. According to the definition of HP 12, only the H 2 S emission of substances with hazard statement EUH031 is accounted for. In view of the calcium content of the two air pollution control residue, the presence of calcium sulphide (EUH031) can be assumed. These two waste are therefore classified potentially hazardous for HP 12, from a total of 49 waste. They are also classified as hazardous for other properties (HP 7

Evaluating the toxic effects of three priority hazardous and noxious substances (HNS) to rotifer Brachionus plicatilis.

Science.gov (United States)

Zheng, Lei; Pan, Luqing; Lin, Pengfei; Miao, Jingjing; Wang, Xiufen; Lin, Yufei; Wu, Jiangyue

2017-12-01

Hazardous and noxious substances (HNS) spill in the marine environment is an issue of growing concern, and it will mostly continue to do so in the future owing to the increase of high chemical traffic. Nevertheless, the effects of HNS spill on marine environment, especially on aquatic organisms are unclear. Consequently, it is emergent to provide valuable information for the toxicities to marine biota caused by HNS spill. Accordingly, the acute toxicity of three preferential HNS and sub-lethal effects of acrylonitrile on Brachionus plicatilis were evaluated. The median lethal concentration (LC 50 ) at 24 h were 47.2 mg acrylonitrile L -1 , 276.9 mg styrene L -1 , and 488.3 mg p-xylene L -1 , respectively. Sub-lethal toxicity effects of acrylonitrile on feeding behavior, development, and reproduction parameters of B. plicatilis were also evaluated. Results demonstrated that rates of filtration and ingestion were significantly reduced at 2.0, 4.0, and 8.0 mg L -1 of acrylonitrile. Additionally, reproductive period, fecundity, and life span were significantly decreased at high acrylonitrile concentrations. Conversely, juvenile period was significantly increased at the highest two doses and no effects were observed on embryonic development and post-reproductive period. Meanwhile, we found that ingestion rate decline could be a good predictor of reproduction toxicity in B. plicatilis and ecologically relevant endpoint for toxicity assessment. These data will be useful to assess and deal with marine HNS spillages.

Korean research project on the integrated exposure assessment of hazardous substances for food safety

Directory of Open Access Journals (Sweden)

Ji-Ae Lim

2015-06-01

Full Text Available Objectives: This survey was designed to conduct the first nationwide dietary exposure assessment on hazardous substances including the intakes of functional food and herbal medicine. In this paper, we introduced the survey design and the results of the dietary exposure status and internal exposure levels of lead (Pb, cadmium (Cd, and mercury (Hg. Methods: We selected 4867 subjects of all ages throughout Korea. We conducted a food survey, dietary survey, biomonitoring, and health survey. Results: Pb and Cd were the highest (median value in the seaweed (94.2 μg/kg for Pb; 594 μg/kg for Cd, and Hg was the highest in the fish (46.4 μg/kg. The dietary exposure level (median value of Pb was 0.14 μg/kg body weight (bw/d, 0.18 μg/kg bw/d for Cd, and 0.07 μg/kg bw/d for Hg. Those with a blood Pb level of less than 5.00 μg/dL (US Centers for Disease Control and Prevention, reference value for those 1 to 5 years of age were 99.0% of all the subjects. Those with a blood Cd level with less than 0.30 μg/L (German Federal Environmental Agency, reference value for non-smoking children were 24.5%. For those with a blood Hg level with less than 5.00 μg/L (human biomonitoring I, references value for children and adults, German Federal Environmental Agency was 81.0 % of all the subjects. Conclusions: The main dietary exposure of heavy metals occurs through food consumed in a large quantity and high frequency. The blood Hg level and dietary exposure level of Hg were both higher than those in the European Union.

78 FR 2333 - Approval of the Clean Air Act, Section 112(l), Authority for Hazardous Air Pollutants: Asbestos...

Science.gov (United States)

2013-01-11

...] Approval of the Clean Air Act, Section 112(l), Authority for Hazardous Air Pollutants: Asbestos Management... protection, Administrative practice and procedure, Air pollution control, Hazardous substances, Incorporation...-Sw 2100: Management and Control of Asbestos Disposal Sites Not Operated after July 9, 1981,'' and the...

Exposure to hazardous substances in Cathode Ray Tube (CRT) recycling sites in France

Energy Technology Data Exchange (ETDEWEB)

Lecler, Marie-Thérèse, E-mail: marie-therese.lecler@inrs.fr; Zimmermann, François; Silvente, Eric; Clerc, Frédéric; Chollot, Alain; Grosjean, Jérôme

2015-05-15

Highlights: • Chemical risks were assessed in the nine cathode ray tube screens recycling facilities. • The main hazardous agents are dust containing lead, cadmium, barium and yttrium. • Exposure and pollutant levels are described for different operations and processes. • All the operations and processes are concerned by significant levels of pollutants. • We suggest recommendations to reduce chemical risk. - Abstract: The Waste Electrical and Electronic Equipment (WEEE) or e-waste recycling sector has grown considerably in the last fifteen years due to the ever shorter life cycles of consumables and an increasingly restrictive policy context. Cathode Ray Tubes (CRTs) from used television and computer screens represent one of the main sources of e-waste. CRTs contain toxic materials such as lead, cadmium, barium, and fluorescent powders which can be released if recycling of CRTs is not appropriate. Exposure to these harmful substances was assessed in nine workshops where CRT screens are treated. Particulate exposure levels were measured using a gravimetric method and metals were analysed by plasma emission spectrometry. The maximum levels of worker exposure were 8.8 mg/m{sup 3}, 1504.3 μg/m{sup 3}, 434.9 μg/m{sup 3}, 576.3 μg/m{sup 3} and 2894.3 μg/m{sup 3} respectively for inhalable dust, barium, cadmium, lead and yttrium. The maximum levels of airborne pollutants in static samples were 39.0 mg/m{sup 3}, 848.2 μg/m{sup 3}, 698.4 μg/m{sup 3}, 549.3 μg/m{sup 3} and 3437.9 μg/m{sup 3} for inhalable dust, barium, cadmium, lead and yttrium. The most harmful operations were identified, and preventive measures for reducing the chemical risk associated with screen recycling were proposed. Workplace measurements were used to define recommendations for reducing the chemical risks in CRT screens recycling facilities and for promoting the design and development of “clean and safe” processes in emerging recycling channels.

Risk assessment of hazardous impacts on urbanization and industrialization activities based upon toxic substances

Directory of Open Access Journals (Sweden)

T. Salem

2016-03-01

Full Text Available A risk assessment study was conducted to predict the expected hazardous influence on the ecosystem resulted from urbanization and industrialization activities at Helwan area, Egypt. To achieve these goals, soils, plants and water samples were collected from Helwan area, and their total concentrations of inorganic contaminants (Cd, Cr, Co, Cu, Fe, Mn, Ni, Pb, and Zn and organic pollutants; such as Phenol and hydrocarbons were measured. The obtained results showed that, the concentrations of organic contaminants in water streams and surrounding soils recorded high concentration values than the permissible limits, while inorganic elements were within the safe limits for irrigation. In addition, soils irrigated with the effluents of industrial units recorded high values of inorganic and organic contaminants. Consequently, the levels of these contaminants were high in plant tissues grown thereon; especially the edible parts. Risk assessment based on available Predicted No Effect Concentration values for the aquatic and terrestrial environment was performed. Inorganic elements were expected to cause serious hazard problems for both aquatic organisms and soil microorganisms. The impact of these pollutants on human health was calculated using daily metals intake of inorganic metals via consumption of edible plants. Hazard index values proved that concentrations of Cr may cause serious hazard problems for humans in this area; especially, children.

The development of the globally harmonized system (GHS) of classification and labelling of hazardous chemicals

International Nuclear Information System (INIS)

Winder, Chris; Azzi, Rola; Wagner, Drew

2005-01-01

The hazards of chemicals can be classified using classification criteria that are based on physical, chemical and ecotoxicological endpoints. These criteria may be developed be iteratively, based on scientific or regulatory processes. A number of national and international schemes have been developed over the past 50 years, and some, such as the UN Dangerous Goods system or the EC system for hazardous substances, are in widespread use. However, the unnecessarily complicated multiplicity of existing hazard classifications created much unnecessary confusion at the user level, and a recommendation was made at the 1992 Rio Earth summit to develop a globally harmonized chemical hazard classification and compatible labelling system, including material safety data sheets and easily understandable symbols, that could be used for manufacture, transport, use and disposal of chemical substances. This became the globally harmonized system for the Classification and Labelling of Chemicals (GHS). The developmental phase of the GHS is largely complete. Consistent criteria for categorising chemicals according to their toxic, physical, chemical and ecological hazards are now available. Consistent hazard communication tools such as labelling and material safety data sheets are also close to finalisation. The next phase is implementation of the GHS. The Intergovernmental Forum for Chemical Safety recommends that all countries implement the GHS as soon as possible with a view to have the system fully operational by 2008. When the GHS is in place, the world will finally have one system for classification of chemical hazards

Ministerial Order appointing the Customs Offices through which radioactive substances or devices containing such substances subject to licensing must be imported

International Nuclear Information System (INIS)

1977-01-01

Under the royal Order of 28 February 1963 regulating protection of the population and workers against the hazards of ionizing radiation, this Order by the Minister of Public Health and the Family designates the Customs Offices through which radioactive substances and devices containing them may be imported. It lists for each type of transport (land, sea etc) the authorised points of access into Belgium. (NEA) [fr

An evaluation of approximations of acute hazard indices based on chronic hazard indices for California fossil-fuel power stations

International Nuclear Information System (INIS)

Gratt, L.B.; Levin, L.

1998-01-01

The measures for evaluating risk under the Clean Air Act Amendments of 1990 are yet to be defined. Many risk assessments have used only chronic risk measures (lifetime cancer probability and chronic hazard index) based on yearly averages of long-term dispersion of substances into ambient air. In California, many facilities prepared risk assessments using hourly meteorological data and short-term emission rates, allowing the calculation of an acute hazard index. These risk assessments are more costly and labor-intensive than those using the annualized meteorological data. A simple scheme to estimate the acute hazard index from the chronic index is proposed. This scheme is evaluated for four electric power stations in Southern California. The simple scheme was found lacking due to the inability to reasonably estimate both the hourly emission rates from annual averages and hourly concentrations from annual concentrations. The need for the acute risk measure for stack emission can be questioned based on the more detailed risk assessments performed in California

Sustainable System for Residual Hazards Management

International Nuclear Information System (INIS)

Kevin M. Kostelnik; James H. Clarke; Jerry L. Harbour

2004-01-01

Hazardous, radioactive and other toxic substances have routinely been generated and subsequently disposed of in the shallow subsurface throughout the world. Many of today's waste management techniques do not eliminate the problem, but rather only concentrate or contain the hazardous contaminants. Residual hazards result from the presence of hazardous and/or contaminated material that remains on-site following active operations or the completion of remedial actions. Residual hazards pose continued risk to humans and the environment and represent a significant and chronic problem that require continuous long-term management (i.e. >1000 years). To protect human health and safeguard the natural environment, a sustainable system is required for the proper management of residual hazards. A sustainable system for the management of residual hazards will require the integration of engineered, institutional and land-use controls to isolate residual contaminants and thus minimize the associated hazards. Engineered controls are physical modifications to the natural setting and ecosystem, including the site, facility, and/or the residual materials themselves, in order to reduce or eliminate the potential for exposure to contaminants of concern (COCs). Institutional controls are processes, instruments, and mechanisms designed to influence human behavior and activity. System failure can involve hazardous material escaping from the confinement because of system degradation (i.e., chronic or acute degradation) or by external intrusion of the biosphere into the contaminated material because of the loss of institutional control. An ongoing analysis of contemporary and historic sites suggests that the significance of the loss of institutional controls is a critical pathway because decisions made during the operations/remedial action phase, as well as decisions made throughout the residual hazards management period, are key to the long-term success of the prescribed system. In fact

Association of Substance Use Disorders With Conversion From Schizotypal Disorder to Schizophrenia.

Science.gov (United States)

Hjorthøj, Carsten; Albert, Nikolai; Nordentoft, Merete

2018-04-25

Understanding the role of substance use disorders in conversion from schizotypal disorder to schizophrenia may provide physicians and psychiatrists with important tools for prevention or early detection of schizophrenia. To investigate whether substance use disorders, in particular cannabis use disorder, are associated with conversion to schizophrenia in individuals with schizotypal disorder. This prospective cohort study included a population-based sample of all individuals born in Denmark from January 1, 1981, through August 10, 2014, with an incident diagnosis of schizotypal disorder and without a previous diagnosis of schizophrenia. Follow-up was completed on August 10, 2014, and data were analyzed from March 10, 2017, through February 15, 2018. Information on substance use disorders combined from 5 different registers. Cox proportional hazards regression using time-varying information on substance use disorders and receipt of antipsychotics and adjusted for parental history of mental disorders, sex, birth year, and calendar year were used to estimate hazard ratios (HRs) and 95% CIs for conversion to schizophrenia. A total of 2539 participants with incident schizotypal disorder were identified (1448 men [57.0%] and 1091 women [43.0%]; mean [SD] age, 20.9 [4.4] years). After 2 years, 16.3% (95% CI, 14.8%-17.8%) experienced conversion to schizophrenia. After 20 years, the conversion rate was 33.1% (95% CI, 29.3%-37.3%) overall and 58.2% (95% CI, 44.8%-72.2%) among those with cannabis use disorders. In fully adjusted models, any substance use disorder was associated with conversion to schizophrenia (HR, 1.34; 95% CI, 1.11-1.63). When data were stratified by substance, cannabis use disorders (HR, 1.30; 95% CI, 1.01-1.68), amphetamine use disorders (HR, 1.90; 95% CI, 1.14-3.17), and opioid use disorders (HR, 2.74; 95% CI, 1.38-5.45) were associated with conversion to schizophrenia. These associations were not explained by concurrent use of antipsychotics, functional

Metal food packaging design based on hazard analysis critical control point (HACCP system in canned food safety

Directory of Open Access Journals (Sweden)

Li Xingyi

2016-06-01

Full Text Available This study aims to design metal food packaging with hazard analysis critical control point (HACCP. First, theory of HACCP was introduced in detail. Taking empty cans provided by Wuxi Huapeng Food Packaging Company as an example, we studied migration of bisphenol compounds in coating of food can to food stimulant. Moreover, packaging design of luncheon meat can was taken as an example to confirm whether HACCP system could effectively control migration of phenolic substance. Results demonstrated that, coating of such empty were more likely to contain multiple bisphenol compounds such as bisphenol A (BPA, and bisphenol A diglycidyl ether (BADGE was considered as the leading bisphenol pollutant; food stimulant of different types, storage temperature and time could all impact migration of bisphenol compounds. HACCP system was proved to be effective in controlling hazards of phenolic substance in luncheon meat can and could reduce various phenolic substance indexes to an acceptable range. Therefore, HACCP can control migration of phenolic substance and recontamination of food and thus ensure food safety.

Hazardous Waste Remedial Actions Program annual progress report, FY 1990

Energy Technology Data Exchange (ETDEWEB)

1990-12-01

The Hazardous Waste Remedial Actions Programs (HAZWRAP), a unit of Martin Marietta Energy Systems, Inc., supports the Department of Energy (DOE) Oak Ridge Operations Office in broadly environmental areas, especially those relating to waste management and environmental restoration. HAZWRAP comprises six program areas, which are supported by central administrative and technical organizations. Existing programs deal with airborne hazardous substances, pollution prevention, remedial actions planning, environmental restoration, technology development, and information and data systems. HAZWRAP's mission to develop, promote, and apply-cost-effective hazardous waste management and environmental technologies to help solve national problems and concerns. HAZWRAP seeks to serve as integrator for hazardous waste and materials management across the federal government. It applies the unique combination of research and development (R D) capabilities, technologies, management expertise, and facilities in the Energy Systems complex to address problems of national importance. 24 figs., 10 tabs.

EFSA BIOHAZ Panel (EFSA Panel on Biologicial Hazards), 2013. Scientific Opinion on the public health hazards to be covered by inspection of meat (solipeds)

DEFF Research Database (Denmark)

Hald, Tine; Baggesen, Dorte Lau

2013-01-01

A risk ranking process identified Trichinella spp. as the most relevant biological hazard in the context of meat inspection of domestic solipeds. Without a full and reliable soliped traceability system, it is considered that either testing all slaughtered solipeds for Trichinella spp., or inactiv......A risk ranking process identified Trichinella spp. as the most relevant biological hazard in the context of meat inspection of domestic solipeds. Without a full and reliable soliped traceability system, it is considered that either testing all slaughtered solipeds for Trichinella spp...... for chemical hazards should be more flexible and based on the risk of occurrence, taking into account Food Chain Information (FCI), covering the specific on-farm environmental conditions and individual animal treatments, and the ranking of chemical substances, which should be regularly updated and include new...

EFFECTS OF EXPOSURE TO HAZARDOUS SUBSTANCES IN POTTERY AND CERAMIC WORKERS

OpenAIRE

BASARAN, Nursen; ANLAR, Hatice Gul; BACANLI, Merve; SHUBAIR, Mohammed; BAL, Ceylan; TUTKUN, Engin; YILMAZ, Hinc

2018-01-01

During the last decade, the production and hence, the amount andthe types of exposure of hazardous chemicals have been increased in theoccupationally exposed workers. Most of these chemicals have deterious effectsin the living systems. The level of chemical exposure in the occupationalsettings and the biomonitoring of workers and also establishing the regulatoryendpoints are very important. The exposures of chemicals in the workplaces havebeen associated with the increase in allergy, organ an...

Substance Misuse in the Psychiatric Emergency Service; A Descriptive Study

Directory of Open Access Journals (Sweden)

Yves Chaput

2014-01-01

Full Text Available Substance misuse is frequently encountered in the psychiatric emergency service (PES and may take many forms, ranging from formal DSM-IV diagnoses to less obvious entities such as hazardous consumption. Detecting such patients using traditional screening instruments has proved problematic. We therefore undertook this study to more fully characterize substance misuse in the PES and to determine whether certain variables might help better screen these patients. We used a prospectively acquired database of over 18,000 visits made to four PESs during a 2-year period in the province of Quebec, Canada. One of the variables acquired was a subjective rating by the nursing staff as to whether substance misuse was a contributing factor to the visit (graded as direct, indirect, or not at all. Substance misuse accounted for 21% of all diagnoses and alcohol was the most frequent substance used. Patients were divided into those with primary (PSM, comorbid (CSM or no substance misuse (NSM. Depressive disorders were the most frequent primary diagnoses in CSM, whereas personality and substance misuse disorders were frequent secondary diagnoses in PSM. Although many variables significantly differentiated the three groups, few were sufficiently detailed to be used as potential screening tools. Those situations that did have sufficient details included those with a previous history of substance misuse, substance misuse within 48 hours of the visit, and visits graded by the nursing staff as being directly and/or indirectly related to substance misuse. Variables related to substance misuse itself were the primary predictors of PSM and, less significantly, CSM. The nursing staff rating, although promising, was obtained in less than 30% of all visits, rendering its practical use difficult to assess.

Emergency planning for industrial hazards

International Nuclear Information System (INIS)

Gow, H.B.F.; Kay, R.W.

1988-01-01

The European Communities have produced a Directive on the Major Accident Hazards of Certain Industrial Activities which sets out standards for the control and mitigation of the hazards presented by sites and storages which contain significant quantities of dangerous substances. An essential element of these controls is the provision of effective on-and off-site emergency plans. This conference explores the considerable research effort which is going on throughout the world in the improvement of systems for emergency planning. Attention was also drawn to areas where difficulties still exist, for example in predicting the consequences of an accident, the complexities of communication problems and the difficulties arising from involvement of the public. The proceedings are in six parts which deal with organizations implementing emergency planning: on- and off-site emergency planning and design; techniques for emergency plans; expenses and auditing of emergency plans; lessons learnt from the emergency management of major accidents; information to the public to and during emergencies. (author)

New free Danish online (Q)SAR predictions database with >600,000 substances

DEFF Research Database (Denmark)

Wedebye, Eva Bay; Dybdahl, Marianne; Reffstrup, Trine Klein

Since 2005 the Danish (Q)SAR Database has been freely available on the Internet. It is a tool that allows single chemical substance profiling and screenings based on predicted hazard information. The database is also included in the OECD (Q)SAR Application Toolbox which is used worldwide...... by regulators and industry. A lot of progress in (Q)SAR model development, application and documentation has been made since the publication in 2005. A new and completely rebuild online (Q)SAR predictions database was therefore published in November 2015 at http://qsar.food.dtu.dk. The number of chemicals...... in the database has been expanded from 185,000 to >600,000. As far as possible all organic single constituent substances that were pre-registered under REACH have been included in the new structure set. The new Danish (Q)SAR Database includes estimates from more than 200 (Q)SARs covering a wide range of hazardous...

In the shadow of the Cosmetic Directive--inconsistencies in EU environmental hazard classification requirements for UV-filters.

Science.gov (United States)

Sobek, A; Bejgarn, S; Rudén, C; Molander, L; Breitholtz, M

2013-09-01

UV-filters are chemicals with potentially environmental hazardous properties. In the European Union (EU), UV-filters contained in sunscreen products are currently regulated by the Cosmetic Directive (from July 2013 by the Cosmetic Products Regulation). Environmental hazard classifications according to the regulation on classification, labelling and packaging of substances and mixtures (CLP) must be determined for UV-filters contained in industrial chemical products, whereas UV-filters contained in sunscreens are exempted from CLP. In this study we determined the potential environmental hazard classifications of UV-filters and sunscreen products if the CLP regulation was to be required for cosmetic products. Two sunscreen products were evaluated in accordance with the aquatic environmental hazard criteria for mixtures. The results highlight that the inconsistencies in the current EU regulation of UV filters hamper the risk management of environmental hazards of UV filters used in cosmetic products. Almost 50% of the investigated UV-filters approved for use in cosmetic products on the European market according to the current Cosmetic Directive were identified to meet the CLP classification as being hazardous to the aquatic environment. Assuming a worst-case scenario, the two examined sunscreens could both be classified as hazardous to the aquatic environment with long-lasting effects according to CLP classification criteria. Hence, if the CLP regulation was applicable to sunscreen products, both brands could potentially be labelled with the environmental hazard pictogram and associated hazard and precautionary statements. Including cosmetic products, and thereby sunscreens, in the CLP regulation would contribute to a more harmonized and transparent regulation of potentially hazardous substances on the EU market. Copyright © 2013 Elsevier B.V. All rights reserved.

Problems of substance abuse: exploitation and control.

Science.gov (United States)

Ray, L

1985-01-01

The notion of substance abuse is highly problematic. There is considerable disagreement amongst 'experts' as to the relative hazards and addictive properties of both legally and illegally available substances. There are also widely divergent sub-cultural attitudes to the harmfulness or benefit of drug use. One can assume no social consensus as to the nature of the contemporary 'drug problem', nor about the most appropriate means of dealing with it. There is, however, considerable evidence that criminalization of drug use, and harsh penalties against users and suppliers, are ineffective and counter-productive. Other models of control need to be considered, and in particular the merits and de-merits of the medicalization of drug abuse require examination. However, this is only one aspect of the problem. On the other side are the national and international corporations and syndicates, both legitimate and criminal, that earn vast profits from trade in toxic substances. Tobacco is legally available in every country in the world, and the industry is rarely subject to strict control. Thus the issue of substance abuse and control should be seen in a global context, in which account is taken of both legitimate and underworld operations. In attempts to control international trade in toxic substances, the limited success and the problems of already existing legal controls should be acknowledged. Local awareness and regulation of trade in substances is essential, but not sufficient. Amongst other avenues to be explored is the possibility of diverting presently illicitly grown narcotics into indigenous pharmaceutical industries in the Third World. Some problems with this strategy are noted.(ABSTRACT TRUNCATED AT 250 WORDS)

Toxicity of seven priority hazardous and noxious substances (HNSs) to marine organisms: Current status, knowledge gaps and recommendations for future research

International Nuclear Information System (INIS)

Rocha, A. Cristina S.; Reis-Henriques, Maria Armanda; Galhano, Victor; Ferreira, Marta; Guimarães, Laura

2016-01-01

Shipping industry and seaborne trade have rapidly increased over the last fifty years, mainly due to the continuous increasing demand for chemicals and fuels. Consequently, despite current regulations, the occurrence of accidental spills poses an important risk. Hazardous and noxious substances (HNSs) have been raising major concern among environmental managers and scientific community for their heterogeneity, hazardous potential towards aquatic organisms and associated social-economic impacts. A literature review on ecotoxicological hazards to aquatic organisms was conducted for seven HNSs: acrylonitrile, n-butyl acrylate, cyclohexylbenzene, hexane, isononanol, trichloroethylene and xylene. Information on the mechanisms of action of the selected HNS was also reviewed. The main purpose was to identify: i) knowledge gaps in need of being addressed in future research; and ii) a set of possible biomarkers suitable for ecotoxicological assessment and monitoring in both estuarine and marine systems. Main gaps found concern the scarcity of information available on ecotoxicological effects of HNS towards marine species and their poorly understood mode of action in wildlife. Differences were found between the sensitivity of freshwater and seawater organisms, so endpoints produced in the former may not be straightforwardly employed in evaluations for the marine environment. The relationship between sub-individual effects and higher level detrimental alterations (e.g. behavioural, morphological, reproductive effects and mortality) are not fully understood. In this context, a set of biomarkers associated to neurotoxicity, detoxification and anti-oxidant defences is suggested as potential indicators of toxic exposure/effects of HNS in marine organisms. Overall, to support the development of contingency plans and the establishment of environmental safety thresholds, it will be necessary to undertake targeted research on HNS ecotoxicity in the marine environment. Research should

Toxicity of seven priority hazardous and noxious substances (HNSs) to marine organisms: Current status, knowledge gaps and recommendations for future research

Energy Technology Data Exchange (ETDEWEB)

Rocha, A. Cristina S., E-mail: cristinasrocha@gmail.com; Reis-Henriques, Maria Armanda; Galhano, Victor; Ferreira, Marta, E-mail: marta.ferreira@usp.ac.fj; Guimarães, Laura

2016-01-15

Shipping industry and seaborne trade have rapidly increased over the last fifty years, mainly due to the continuous increasing demand for chemicals and fuels. Consequently, despite current regulations, the occurrence of accidental spills poses an important risk. Hazardous and noxious substances (HNSs) have been raising major concern among environmental managers and scientific community for their heterogeneity, hazardous potential towards aquatic organisms and associated social-economic impacts. A literature review on ecotoxicological hazards to aquatic organisms was conducted for seven HNSs: acrylonitrile, n-butyl acrylate, cyclohexylbenzene, hexane, isononanol, trichloroethylene and xylene. Information on the mechanisms of action of the selected HNS was also reviewed. The main purpose was to identify: i) knowledge gaps in need of being addressed in future research; and ii) a set of possible biomarkers suitable for ecotoxicological assessment and monitoring in both estuarine and marine systems. Main gaps found concern the scarcity of information available on ecotoxicological effects of HNS towards marine species and their poorly understood mode of action in wildlife. Differences were found between the sensitivity of freshwater and seawater organisms, so endpoints produced in the former may not be straightforwardly employed in evaluations for the marine environment. The relationship between sub-individual effects and higher level detrimental alterations (e.g. behavioural, morphological, reproductive effects and mortality) are not fully understood. In this context, a set of biomarkers associated to neurotoxicity, detoxification and anti-oxidant defences is suggested as potential indicators of toxic exposure/effects of HNS in marine organisms. Overall, to support the development of contingency plans and the establishment of environmental safety thresholds, it will be necessary to undertake targeted research on HNS ecotoxicity in the marine environment. Research should

40 CFR 261.8 - PCB wastes regulated under Toxic Substance Control Act.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false PCB wastes regulated under Toxic... (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE General § 261.8 PCB wastes regulated under Toxic Substance Control Act. The disposal of PCB-containing dielectric fluid and electric...

Transportation of hazardous materials in Iran: A strategic approach for decreasing accidents

Directory of Open Access Journals (Sweden)

S. Ghazinoory

2008-06-01

Full Text Available .“Hazardous materials” refer to those substances that seriously endanger human lives and/or the environment. The transportation of these materials will be inevitable in the increasingly industrialized economy of Iran. Nonetheless, numerous deadly accidents caused by the movement of these materials necessitate the design and implementation of preventive plans on several levels. This article looks into the present condition of transportation of hazardous materials in Iran and the resulting accidents. Optimal condition for the general transportation system of hazardous materials is delineated with due focus on transportation risk as the main parameter. Strategies for reaching the optimal condition are laid out and the impacts of these strategies on the reduction of accidents are analyzed.

[Information content of immunologic parameters in the evaluation of the effects of hazardous substances].

Science.gov (United States)

Litovskaia, A V; Sadovskiĭ, V V; Vifleemskiĭ, A B

1995-01-01

Clinical and immunologic examination including 1 and 2 level tests covered 429 staffers of chemical enterprises and 1122 of those engaged into microbiological synthesis of proteins, both the groups exposed to some irritating gases and isocyanates. Using calculation of Kulbak's criterion, the studies selected informative parameters to diagnose immune disturbances caused by occupational hazards. For integral evaluation of immune state, the authors applied general immunologic parameter, meanings of which can serve as criteria for early diagnosis of various immune disorders and for definition of risk groups among industrial workers exposed to occupational biologic and chemical hazards.

Drug delivery and nanoparticles: Applications and hazards

Directory of Open Access Journals (Sweden)

Wim H De Jong

2008-06-01

Full Text Available Wim H De Jong1, Paul JA Borm2,31Laboratory for Toxicology, Pathology and Genetics, National Institute for Public Health and the Environment (RIVM, Bilthoven, The Netherlands; 2Zuyd University, Centre of Expertise in Life Sciences, Heerlen, The Netherlands; 3Magnamedics GmbH, Aachen, GermanyAbstract: The use of nanotechnology in medicine and more specifically drug delivery is set to spread rapidly. Currently many substances are under investigation for drug delivery and more specifically for cancer therapy. Interestingly pharmaceutical sciences are using nanoparticles to reduce toxicity and side effects of drugs and up to recently did not realize that carrier systems themselves may impose risks to the patient. The kind of hazards that are introduced by using nanoparticles for drug delivery are beyond that posed by conventional hazards imposed by chemicals in classical delivery matrices. For nanoparticles the knowledge on particle toxicity as obtained in inhalation toxicity shows the way how to investigate the potential hazards of nanoparticles. The toxicology of particulate matter differs from toxicology of substances as the composing chemical(s may or may not be soluble in biological matrices, thus influencing greatly the potential exposure of various internal organs. This may vary from a rather high local exposure in the lungs and a low or neglectable exposure for other organ systems after inhalation. However, absorbed species may also influence the potential toxicity of the inhaled particles. For nanoparticles the situation is different as their size opens the potential for crossing the various biological barriers within the body. From a positive viewpoint, especially the potential to cross the blood brain barrier may open new ways for drug delivery into the brain. In addition, the nanosize also allows for access into the cell and various cellular compartments including the nucleus. A multitude of substances are currently under investigation

29 CFR 1918.93 - Hazardous atmospheres and substances (See also § 1918.2).

Science.gov (United States)

2010-07-01

...; § 1918.94(e), Catch of menhaden and similar species of fish. (b) Determination of the hazard. When the...-contained breathing apparatus which shall be used for entry. (4) To prevent inadvertent employee entry into...

Various possible ways to express the toxicity of radioactive substances in relation with the involved practical problems; Diverses expressions possibles de la toxicite des substances radioactives en fonction des problemes pratiques poses

Energy Technology Data Exchange (ETDEWEB)

Jammet, H; Vacca, G [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

1959-07-01

Radioelements have at the same time physico-chemical and radioactive properties. It is then possible to establish two types of toxicological classifications: one in function of the weight of the radioelement, another in function of its activity. More often, the maximum permissible amounts (MPA) in the human body and the maximum permissible concentrations (MPC) in air and water are expressed in microcuries by millilitre ({mu}c/ml), less frequently in micrograms by millilitre ({mu}g/ml). The comparison of these tables of MPA and MPC shows important differences in the classification of radioactive substances by order of decreasing toxicity. Plutonium and radium, being among the most toxic products when the activity is considered are far from being the most dangerous when the weight is considered. On the other hand, {sup 131}I and {sup 56}Mn, for instance appear to be among the most hazardous substances in this eventuality. This twofold consideration corresponds to two aspects of the problems of the toxicity of radioisotopes. The classification by activity is almost exclusively utilised because the toxicological measurements are based on the radioactive properties of the radioisotopes. In general, only these measurements allow to detect the very small amounts of substance usually involved. On the other hand, the toxicity related to internal contamination by radioisotopes depends mostly from their metabolism which is exclusively a function of their physico-chemical properties. Therefore the classification by weight gives the best representation of the hazards encountered when radioactive substances are inhaled or ingested. As a result, the relative toxicity of radioisotopes cannot be based on the classification by activity only. The present division of radioisotopes into different classes: very hazardous, moderately hazardous, slightly hazardous must be revised. (author) [French] Les radioelements presentent a la fois des proprietes physico-chimiques banales et des

Hazard and precautionary measures in connection with negligent or wilful contamination

International Nuclear Information System (INIS)

Ahlfaenger, Rainer; Scheidegger, Roland

2009-01-01

Handling open radioactive substances requires extensive precautionary measures in order to avoid any danger. During the past 100 years many persons were injured or killed due to unintended external irradiation, contamination of the skin or uptake of radioactive substances. With the help of organisational measures with users of sources and with operators of radionuclide laboratories or nuclear installations numerous accidents can be avoided or their consequences can be mitigated. Also the government itself is challenged in order to register and secure radioactive sources and maintaining the national safeguard. Education of personnel handling radioactive substances plays an important role when it comes to precautionary measures. In combination with suitable technical equipment it is possible to obtain a high degree of protection against the hazard from negligent or wilful contamination. (orig.)

Confidence Limits for Hazardous Concentrations Based on Logistically Distributed NOEC Toxicity Data

NARCIS (Netherlands)

Aldenberg T; Slob W

1991-01-01

This paper deals with the calculation of Hazardous Concentrations of toxic substances from small sets of laboratory toxicity data, e.g. NOECs. A procedure due to Van Straalen and Denneman, as adapted from Kooijman (case n=1), in which one seeks a concentration that protects 95% of the biological

75 FR 33724 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2010-06-15

... at the site or the customer's shop, if needed. During the mid-1980s, the southern portion of the Site... substances identified in the Selected Remedy for Operable Unit 1 of the Site. The ground water flows to the...

Applicability of concentration factors for the heavy metals hazard identification

International Nuclear Information System (INIS)

Guzzi, Luigi

2006-01-01

The bioconcentration factor (BCF) and bioaccumulation factor (BAF) used as criteria for heavy metals hazards identification are inadequate. These considerations is based on the argument that the BCF-BAF model was developed and validated for xenobiotic synthetic organic substances and that does not recognize the complex internal metal dynamic of uptake, the internal sequestration, and the essentially of some heavy metals [it

Project plan, Hazardous Materials Management and Emergency Response Training Center: Project 95L-EWT-100

International Nuclear Information System (INIS)

Borgeson, M.E.

1994-01-01

The Hazardous Materials Management and Emergency Response (HAMMER) Training Center will provide for classroom lectures and hands-on practical training in realistic situations for workers and emergency responders who are tasked with handling and cleanup of toxic substances. The primary objective of the HAMMER project is to provide hands-on training and classroom facilities for hazardous material workers and emergency responders. This project will also contribute towards complying with the planning and training provisions of recent legislation. In March 1989 Title 29 Code of Federal Regulations Occupational Safety and Health Administration 1910 Rules and National Fire Protection Association Standard 472 defined professional requirements for responders to hazardous materials incidents. Two general types of training are addressed for hazardous materials: training for hazardous waste site workers and managers, and training for emergency response organizations

Presence and fate of priority substances in domestic greywater treatment and reuse systems

DEFF Research Database (Denmark)

Donner, E.; Eriksson, Eva; Revitt, M.

2010-01-01

) or "Priority Hazardous Substances" (PHS). Significant knowledge gaps are identified. A wide range of potential treatment trains are available for greywater treatment and reuse but treatment efficiency data for priority substances and other micropollutants is very limited. Geochemical modelling indicates......A wide range of household sources may potentially contribute to contaminant loads in domestic greywater. The ability of greywater treatment systems to act as emission control barriers for household micropollutants, thereby providing environmental benefits in addition to potable water savings, have...... not been fully explored. This paper investigates the sources, presence and potential fate of a selection of xenobiotic micropollutants in on-site greywater treatment systems. All of the investigated compounds are listed under the European Water Framework Directive as either "Priority Substances" (PS...

Hazard characterization and special considerations for environmental and decontamination and decommissioning activities

International Nuclear Information System (INIS)

Kerr, N.R.

1993-08-01

The mission of the US Department of Energy (DOE) has changed from defense production of special nuclear materials to cleanup of production facilities at the Hanford Site. The DOE contractors have formed the Energy Facility Contractors Group to support this change in mission. In addition, the Safety Analysis Working Subgroup for Environmental Restoration and Decontamination and Decommissioning (ER/D ampersand D) was formed to identify, develop, and share information that supports safety analyses and engineering of ER/D ampersand D activities. Safety analysis is in part the process of identifying and understanding the hazards that could result in exposures to radiological or chemical hazardous substances. The following paragraphs address the special considerations given to hazard characterization for ER/D ampersand D activities

EFSA BIOHAZ Panel (EFSA Panel on Biological Hazards, 2013. Scientific Opinion on the public health hazards to be covered by inspection of meat from sheep and goats

DEFF Research Database (Denmark)

Hald, Tine; Baggesen, Dorte Lau

A risk ranking process identified Toxoplasma gondii and pathogenic verocytotoxin-producing Escherichia coli (VTEC) as the most relevant biological hazards for meat inspection of sheep and goats. As these are not detected by traditional meat inspection, a meat safety assurance system using risk......-based interventions was proposed. Further studies are required on T. gondii and pathogenic VTEC. If new information confirms these hazards as a high risk to public health from meat from sheep or goats, setting targets at carcass level should be considered. Other elements of the system are risk...... the extensive production systems used, and the ranking of chemical substances, which should be regularly updated and include new hazards. Control programmes across the food chain, national residue control plans, feed control and monitoring of environmental contaminants should be better integrated. Meat...

A model used to derive hazardous waste concentration limits aiming at the reduction of toxic and hazardous wastes. Applications to illustrate the discharge of secondary categories types B and C

International Nuclear Information System (INIS)

Paris, P.

1989-11-01

This report describes a model which may be used to derive hazardous waste concentration limits in order to prevent ground water pollution from a landfill disposal. First the leachate concentration limits are determined taking into account the attenuation capacity of the landfill-site as a whole; waste concentrations are then derived by an elution model which assumes a constant ratio between liquid-solid concentrations. In the example two types of landfill have been considered and in each case concentration limits have been calculated for some hazardous substances and compared with the corresponding regulatory limits. (author)

Substance Use Disorders Among Danish Physicians: An Explorative Study of the Professional Socialization and Management of Colleagues With Substance Use Disorders.

Science.gov (United States)

Srensen, Johanne Korsdal; Pedersen, Anette Fischer; Vedsted, Peter; Bruun, Niels Henrik; Christensen, Bo

2016-01-01

This study has 2 aims. Firstly, we explore and analyze the associations between physicians' unhealthy substance use and various work-cultural and social aspects; secondly, we describe how substance use disorder (SUD defined as by Alcohol Use Disorders Identification Test [AUDIT] and Drug Use Disorders Identification Test [DUDIT]) among colleagues is managed and how physicians seek help. During the spring of 2014, a nationwide cross-sectional study was conducted as an anonymous electronic survey among a randomly weighted sample of medical specialists, junior hospital doctors, and general practitioners in Denmark. A total of 4000 physicians (approximately 1333 from each group) were sampled, and 1943 responded (49%). The survey included the AUDIT, the DUDIT, and questions on health and psychological issues. Among the physicians in our study, 18.3% had an AUDIT exceeding 8 (hazardous or harmful alcohol use) and 3.2% had a DUDIT exceeding 1. Of these, 12.9% reported that their substance use had negative consequences for their social networks, and 34% to 42% reported no openness about substance use at their workplace. In total, 4 physicians (1%) of the 383 physicians with risky substance use reported to have been in regular treatment for SUDs. Most of the physicians with an unhealthy consumption of substances (78%) reported that it was irrelevant for them to seek help. Half of them reported that they had limited or insufficient knowledge of SUD. Around 55% of the physicians would encourage colleagues with SUDs to seek treatment. Around 50% of physicians reported that their "SUD knowledge" was relevant, but limited or not satisfactory. One-third never experienced openness about SUD at work. More than half wished to encourage a colleague with SUD to seek treatment. Three quarters of the physicians with unhealthy substance use reported that they found it irrelevant to seek help.

76 FR 21299 - Emergency Planning and Notification; Emergency Planning and List of Extremely Hazardous...

Science.gov (United States)

2011-04-15

... planning quantities (TPQs) for those extremely hazardous substances (EHSs) that are non-reactive solid... need for the community to undertake a program to investigate and evaluate the potential for accidental... the Calculated Index Value''; ``Reactive Solids Whose Threshold Planning Quantities Should Be Less...

Hazardous Material Packaging and Transportation

Energy Technology Data Exchange (ETDEWEB)

Hypes, Philip A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2016-02-04

This is a student training course. Some course objectives are to: recognize and use standard international and US customary units to describe activities and exposure rates associated with radioactive material; determine whether a quantity of a single radionuclide meets the definition of a class 7 (radioactive) material; determine, for a given single radionuclide, the shipping quantity activity limits per 49 Code of Federal Regulations (CFR) 173.435; determine the appropriate radioactive material hazard class proper shipping name for a given material; determine when a single radionuclide meets the DOT definition of a hazardous substance; determine the appropriate packaging required for a given radioactive material; identify the markings to be placed on a package of radioactive material; determine the label(s) to apply to a given radioactive material package; identify the entry requirements for radioactive material labels; determine the proper placement for radioactive material label(s); identify the shipping paper entry requirements for radioactive material; select the appropriate placards for a given radioactive material shipment or vehicle load; and identify allowable transport limits and unacceptable transport conditions for radioactive material.

78 FR 33276 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2013-06-04

..., including learning deficits, lowered intelligence, and adverse effects on behavior. The Integrated Exposure... hazards in the community. Use of mass media (television, radio, internet, print media, etc.) to distribute...

Device with Complex System for Heat Utilization and Reduction of Hazardous Air Emissions

Directory of Open Access Journals (Sweden)

O. V. Kascheeva

2012-01-01

Full Text Available Investigations concern heat utilization and reduction of hazardous emissions occurring in residential buildings and accompanying operation of a great number of industrial enterprises in particular heat and power objects, and firstly, heat-generating units of small power located in densely populated residential areas without centralized heat supply.The investigation target is to reduce cost of heat produced by independent system of building heat supply, reduction of air pollution  due to hazardous gas emissions and reduction of heat pollution of the environment as a result of building ventilation system operation, ventilation of their internal and external sewerage network and higher reliability of their operation.The target is achieved because the device with complex system for heat utilization and reduction of hazardous air emissions has additionally an assembly tank for mixing flue gases, ventilation emissions and atmospheric air, heat pump. Evaporation zone of the pump is a condensator of the gas mixture and its condensate zone contains a heat supply line for a heat consumer. The line is equipped with assembling  and distributing collectors, pipeline connecting the heat supply line with the system of direct and return delivery water from a boiler house, a separator for division of liquid and gaseous mixture phases, neutralizing devices for separate reduction of concentrations of hazardous and odorous substances being released in gaseous and liquid portions of the mixture, a pipeline for periodic supply of air with higher concentration of hazardous and odorous substances in the boiler furnace. The supplied air is obtained as a result of its passing through gas filters at their regeneration when their exchange capacity is exhausted.

Onshore preparedness for hazardous chemical marine vessel accidents: A case study

Directory of Open Access Journals (Sweden)

Faisel T. Illiyas

2016-09-01

Full Text Available Hazardous and noxious substances (HNS are widely transported in marine vessels to reach every part of the world. Bulk transportation of hazardous chemicals is carried out in tank container–carrying cargo ships or in designed vessels. Ensuring the safety of HNS containers during maritime transportation is critically important as the accidental release of any substance may be lethal to the on-board crew and marine environment. A general assumption in maritime accidents in open ocean is that it will not create any danger to the coastal population. The case study discussed in this article throws light on the dangers latent in maritime HNS accidents. An accident involving an HNS-carrying marine vessel in the Arabian Sea near the coast of Yemen became a safety issue to the coastal people of Kasargod District of Kerala, India. The ship carried more than 4000 containers, which were lost to the sea in the accident. Six HNS tank containers were carried by the waves and shored at the populated coast of Kasargod, more than 650 nautical miles east from the accident spot. The unanticipated sighting of tank containers in the coast and the response of the administration to the incident, the hurdles faced by the district administration in handling the case, the need for engaging national agencies and lessons learned from the incident are discussed in the article. This case study has proven that accidents in the open ocean have the potential to put the coastal areas at risk if the on-board cargo contains hazardous chemicals. Littoral nations, especially those close to the international waterlines, must include hazardous chemical spills to their oil spill contingency plans.

RoHS regulated substances in mixed plastics from waste electrical and electronic equipment.

Science.gov (United States)

Wäger, Patrick A; Schluep, Mathias; Müller, Esther; Gloor, Rolf

2012-01-17

The disposal and recovery of plastics from waste electrical and electronic equipment (WEEE) are of considerable importance, both from an environmental and an economic perspective. This paper presents the results of a study investigating current concentrations of hazardous substances in mixed plastics from WEEE and their implications for an environmentally sound recovery. The study included 53 sampling campaigns for mixed plastics from WEEE. The samples were analyzed with regard to heavy metals (cadmium, chromium, mercury, and lead) and flame retardants (PentaBDE, OctaBDE, DecaBDE, DecaBB) regulated in the RoHS Directive. Besides these substances, other brominated flame retardants known to occur in electronics (HBCD, TBBPA) as well as the total bromine and phosphorus contents were considered. Results show that no mixed plastics fraction from WEEE is completely free from substances regulated in the RoHS Directive. The lowest number and average concentrations were found in flat screen monitors. The highest concentrations were found in mixed plastics from CRT monitors and TVs. Mixed plastics fractions with high average concentrations of heavy metals originate from the treatment of small household appliances (cadmium), ICT equipment (lead), and consumer equipment (lead). Mixed plastics fractions with high average concentrations of brominated flame retardants mainly originate from the treatment of small household appliances for high temperature applications (DecaBDE), CRT monitors (OctaBDE and DecaBDE) and consumer equipment (DecaBDE), in particular CRT TVs (DecaBDE). To avoid a dissipation of hazardous substances into plastics and the environment, it is recommended that mixed plastics from WEEE are subject to a strict quality management.

Partition of pollution between dissolved and particulate phases: what about emerging substances in urban stormwater catchments?

Science.gov (United States)

Zgheib, Sally; Moilleron, Régis; Saad, Mohamed; Chebbo, Ghassan

2011-01-01

This paper presents results about the occurrence, the concentrations of urban priority substances on both the dissolved and the particulate phases in stormwater. Samples were collected at the outlet of a dense urban catchment in Paris suburb (2.30 km(2)). 13 chemical groups were investigated including 88 individual substances. Results showed that stormwater discharges contained 45 substances among them some metals, organotins, PAHs, PCBs, alkylphenols, pesticides, phthalates, cholorophenols and one volatile organic compound, i.e. methylene chloride. With respect to the European Water Framework Directive, these substances included 47% of the priority hazardous substances (n = 8), 38% of the priority substances (n = 10). The remaining substances (n = 27) belong to a list of others specific urban substances not included in the Water Framework Directive but monitored during this work. Finally, stormwater quality was evaluated by comparing the substance concentrations to environmental quality standards (EQS) and the particulate content to Canadian sediment quality guidelines. This showed that stormwater was highly contaminated and should be treated before being discharged to receiving waters in order to avoid any adverse impact on the river quality. Copyright © 2010 Elsevier Ltd. All rights reserved.

Household hazardous waste management: a review.

Science.gov (United States)

Inglezakis, Vassilis J; Moustakas, Konstantinos

2015-03-01

This paper deals with the waste stream of household hazardous waste (HHW) presenting existing management systems, legislation overview and other relevant quantitative and qualitative information. European Union legislation and international management schemes are summarized and presented in a concise manner by the use of diagrams in order to provide crucial information on HHW. Furthermore, sources and types, numerical figures about generation, collection and relevant management costs are within the scope of the present paper. The review shows that the term used to refer to hazardous waste generated in households is not clearly defined in legislation, while there is absence of specific acts regulating the management of HHW. The lack of obligation to segregate HHW from the household waste and the different terminology used makes it difficult to determine the quantities and composition of this waste stream, while its generation amount is relatively small and, therefore, is commonly overlooked in waste statistics. The paper aims to cover the gap in the related literature on a subject that is included within the crucial waste management challenges at world level, considering that HHW can also have impact on other waste streams by altering the redox conditions or causing direct reactions with other non hazardous waste substances. Copyright © 2014 Elsevier Ltd. All rights reserved.

The testing of materials within the purview of the laws concerning the control of chemical substances

International Nuclear Information System (INIS)

Bosselmann, K.; Linden, W.

1989-01-01

The main approach adopted for this book is the question of whether and to what extent the commercially available chemical products (ranging from foodstuffs and drugs to pesticides and similar pollutants) have been assessed for environmental and health safety prior to release. The relevant existing laws concerning the testing and characterisation of substances are analysed and compared with a view to the major environmental principle, to prevent chemicals-induced hazards to health and the environment. The book reviews the following laws (and their implementing provisions): law on chemical substances, pesticides, fertilisers, drugs, detergents, leaded petrol, food and feedstuffs, explosives, and transport of hazardous materials. Environmentally significant laws reviewed include the waste management act, the atomic energy act (non-recycable wastes, plutonium, tritium), the water management act, and the act for protection against harmful effects on the environment. (orig./HP) [de

Early substance consumption and problematic use of video games in adolescence

Directory of Open Access Journals (Sweden)

Adélaïde eCOËFFEC

2015-04-01

Full Text Available Substance use as well as use of video games is frequent among young people. The purpose of this research was to study the links between the use of video games and the consumption of various substances such as alcohol, tobacco or cannabis at adolescence. In order to do so, 1423 students from middle and high schools filled an auto-questionnaire that included questions on age, gender, year of study, use of video games and consumptions of alcohol (AUDIT-C, tobacco (HSI and cannabis (CAST. We found that 92.1% of teens use video games and 17.7% have a problematic use of video games (PUVG. Furthermore, results show that substance consumption seems frequent with 19.8% and 8.3% of participants having hazardous alcohol and cannabis consumptions respectively and 5.2% having a moderate to high tobacco dependence. Video gamers consumed significantly more alcohol and gamers with PUVG started their substance consumption (alcohol, tobacco and cannabis earlier. PUVG was found to be negatively correlated to age at first substance consumption, but positively correlated to the time spent playing video games. However, it was not correlated to risks of substance dependence (scores of AUDIT-C, HSI and CAST. Finally, our results are consistent with the literature, in regard to frequency of substance use and use of video games in adolescence. These data will allow for a better consideration of prevention strategies and future care in this particular field.

Suicide and substance use among female veterans: a need for research.

Science.gov (United States)

Chapman, Shawna L Carroll; Wu, Li-Tzy

2014-03-01

The number of female veterans is increasing. Veterans Administration (VA) enrollment increased over 40% from past eras. However, little research has focused on their mental health. We reviewed literature to examine associations of substance use with suicide in female veterans, identify research gaps, and inform future studies. Google Scholar, Pub Med, and PsychINFO were searched using: substance use, female veteran, and suicide. Exclusion criteria (e.g., not discussing U.S. veterans) left 17 articles. Nine studies examined completed suicide among veterans. In most recent years, rates of deaths were greater for veterans than nonveterans, including females. Completed suicide was associated with past trauma, young age, and a mental disorder. Studies have often not addressed substance use. Three studies examined completed suicide among VA treated veterans without examining substance use as an associated factor. Rates of completed suicides were also higher among veterans than nonveterans, including females. A large proportion of females also had a mental diagnosis. Five studies examined substance use and attempted or completed suicide among VA treated veterans. Veterans in poor mental health had increased odds of suicide mortality; women with a substance use disorder (SUD) had a higher hazard ratio for completed suicide than men with a SUD. Engagement in substance abuse treatment decreased odds of suicide attempt among veterans. Available data suggest that suicide rates are higher among female veterans than women in the general population. Substance use may increase the likelihood of suicidal behaviors among female veterans, particularly those with a mental diagnosis. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Chemical dependency: an occupational hazard in the field of anaesthesia.

Science.gov (United States)

Ismail, Samina

2010-10-01

The medical personnel are vulnerable to substance abuse and dependence due to ready access to substance of abuse. Addiction is considered as an occupational hazard for those involved in the practice of anaesthesia for the same reason. Substance abuse is defined as a psychosocial biogenetic disease, which results from dynamic interplay between a susceptible host and favourable environment. According to the 5th and the last National Survey on Drug Abuse (NSDA) in 1993 by Pakistan Narcotic Control, there are nearly three million drug dependants in Pakistan, but no data is available to determine the prevalence among medical or anaesthesia personnel. In order to handle the rising trend of chemical abuse, we need to have more surveys and studies on this subject, written policy and educational programme in postgraduate training with proper control and frequent checking of narcotic dispensing. Reporting of drug abuse and rehabilitation of affected doctors are areas which need to be worked upon.

Bioremediation of toxic and hazardous wastes by denitrifying bacteria

International Nuclear Information System (INIS)

Barraquio, Wilfredo L.

2005-01-01

This papers discusses the wastes coming rom domestic, industrial and agricultural sources are polluting the forests, rivers lakes, groundwater, and air and there are some measures like the physicochemical and biological measures are being utilized to remedy the destruction of resources; and of the measures, bioremediation offers great potential in cleaning up the environment of pollutants which is a cost-effective and environment-friendly technology that uses microorganisms to degrade hazardous substances into less toxic

Increasing worker and community awareness of toxic hazards in the workplace.

Science.gov (United States)

1985-03-01

In November 1984, the Governing Council of the American Public Health Association (APHA) released this position paper on disclosure of occupational health hazards. The Council's action was prompted by the Occupational Health and Safety Administration's (OSHA's) promulgation of a national right-to-know standard that would pre-empt stronger state and local laws protecting an employee's right to be told about hazardous materials in the workplace. The APHA document outlines the dimensions of the toxic substances problem in the United States; argues the need for right-to-know laws; defines the roles of OSHA, unions, and local coalitions for workplace safety; and criticizes the Federal Hazard Communication Standard. Lists of ten essential components of a national right-to-know policy and of four actions the APHA will take to further the worker's right-to-know conclude the paper.

The monitoring of radioactive substances in biological food chains by the veterinary service in Czechoslovakia

Energy Technology Data Exchange (ETDEWEB)

Pawel, O [Central State Veterinary Institute, Prague, Czechoslovakia (Czech Republic)

1986-07-01

Czechoslovakia has established an environmental monitoring system to protect the hygienic conditions of the environment from the radiation hazard. The control authorities of the Ministry of Agriculture and Food take part in this system in order to collect information on the contamination with radioactive substances of soil, plants, game, food animals, foodstuffs and raw materials, i.e. information on all links of the food chain which extends from animals to man. A radioactive substances detection programme has been launched by the appropriate authorities in agriculture, animal husbandry and veterinary service. The programme includes a two-stage laboratory analysis of radioactive substances. The majority of laboratories covering the programme are already in operation.

The monitoring of radioactive substances in biological food chains by the veterinary service in Czechoslovakia

International Nuclear Information System (INIS)

Pawel, O.

1986-01-01

Czechoslovakia has established an environmental monitoring system to protect the hygienic conditions of the environment from the radiation hazard. The control authorities of the Ministry of Agriculture and Food take part in this system in order to collect information on the contamination with radioactive substances of soil, plants, game, food animals, foodstuffs and raw materials, i.e. information on all links of the food chain which extends from animals to man. A radioactive substances detection programme has been launched by the appropriate authorities in agriculture, animal husbandry and veterinary service. The programme includes a two-stage laboratory analysis of radioactive substances. The majority of laboratories covering the programme are already in operation

In the shadow of the Cosmetic Directive — Inconsistencies in EU environmental hazard classification requirements for UV-filters

International Nuclear Information System (INIS)

Sobek, A.; Bejgarn, S.; Rudén, C.; Molander, L.; Breitholtz, M.

2013-01-01

UV-filters are chemicals with potentially environmental hazardous properties. In the European Union (EU), UV-filters contained in sunscreen products are currently regulated by the Cosmetic Directive (from July 2013 by the Cosmetic Products Regulation). Environmental hazard classifications according to the regulation on classification, labelling and packaging of substances and mixtures (CLP) must be determined for UV-filters contained in industrial chemical products, whereas UV-filters contained in sunscreens are exempted from CLP. In this study we determined the potential environmental hazard classifications of UV-filters and sunscreen products if the CLP regulation was to be required for cosmetic products. Two sunscreen products were evaluated in accordance with the aquatic environmental hazard criteria for mixtures. The results highlight that the inconsistencies in the current EU regulation of UV filters hamper the risk management of environmental hazards of UV filters used in cosmetic products. Almost 50% of the investigated UV-filters approved for use in cosmetic products on the European market according to the current Cosmetic Directive were identified to meet the CLP classification as being hazardous to the aquatic environment. Assuming a worst-case scenario, the two examined sunscreens could both be classified as hazardous to the aquatic environment with long-lasting effects according to CLP classification criteria. Hence, if the CLP regulation was applicable to sunscreen products, both brands could potentially be labelled with the environmental hazard pictogram and associated hazard and precautionary statements. Including cosmetic products, and thereby sunscreens, in the CLP regulation would contribute to a more harmonized and transparent regulation of potentially hazardous substances on the EU market. - Highlights: • UV-filters are used in both cosmetic and industrial products/applications • UV-filters in cosmetic products are excluded from CLP • We

Battery collection in municipal waste management in Japan: challenges for hazardous substance control and safety.

Science.gov (United States)

Terazono, Atsushi; Oguchi, Masahiro; Iino, Shigenori; Mogi, Satoshi

2015-05-01

To clarify current collection rules of waste batteries in municipal waste management in Japan and to examine future challenges for hazardous substance control and safety, we reviewed collection rules of waste batteries in the Tokyo Metropolitan Area. We also conducted a field survey of waste batteries collected at various battery and small waste electric and electronic equipment (WEEE) collection sites in Tokyo. The different types of batteries are not collected in a uniform way in the Tokyo area, so consumers need to pay attention to the specific collection rules for each type of battery in each municipality. In areas where small WEEE recycling schemes are being operated after the enforcement of the Act on Promotion of Recycling of Small Waste Electrical and Electronic Equipment in Japan in 2013, consumers may be confused about the need for separating batteries from small WEEE (especially mobile phones). Our field survey of collected waste batteries indicated that 6-10% of zinc carbon and alkaline batteries discarded in Japan currently could be regarded as containing mercury. More than 26% of zinc carbon dry batteries currently being discarded may have a lead content above the labelling threshold of the EU Batteries Directive (2006/66/EC). In terms of safety, despite announcements by producers and municipalities about using insulation (tape) on waste batteries to prevent fires, only 2.0% of discarded cylindrical dry batteries were insulated. Our field study of small WEEE showed that batteries made up an average of 4.6% of the total collected small WEEE on a weight basis. Exchangeable batteries were used in almost all of mobile phones, digital cameras, radios, and remote controls, but the removal rate was as low as 22% for mobile phones. Given the safety issues and the rapid changes occurring with mobile phones or other types of small WEEE, discussion is needed among stakeholders to determine how to safely collect and recycle WEEE and waste batteries. Copyright �

Aqueous media treatment and decontamination of hazardous chemical and biological substances by contact plasma

International Nuclear Information System (INIS)

Pivovarov, A.; Kravchenko, A.; Kublanovsky, V.

2009-01-01

Usage of non-equilibrium contact plasma for processes of decontamination and neutralization in conditions of manifestation of chemical, biological and radiation terrorism takes on special significance due to portability of equipment and its mobility in places where toxic liquid media hazardous for people's health are located. Processes of decontamination of aqueous media, seminated with pathogenic microorganisms and viruses, treatment of water containing toxic heavy metals, cyanides, surface-active substances, and heavy radioactive elements, are investigated. Examples of activation processes in infected water and toxic aqueous solutions present convincing evidence of the way, how new quality technological approach for achievement of high enough degree of the said media treatment is used in each specific case. Among new properties of water activated as a result of action of non-equilibrium contact plasma, it is necessary to mention presence of cluster structure, confirmed by well-known spectral and physical-chemical methods, presence of peroxide compounds, active particles and radicals. Anti-microbial activity which is displayed under action of plasma in aqueous media (chemically pure water, drinking water, aqueous solutions of sodium chloride, potassium iodide, as well as other inorganic compounds) towards wide range of pathogenic and conventionally pathogenic microorganisms allows use them as reliable, accessible and low-cost preparations for increasing the degree of safety of food products. Combination of such processes with known methods of filtration and ultra-filtration gives an efficient and available complex capable of withstanding any threats, which may arise for population and living organisms. Present-day level of machine-building, electrical engineering, and electronics allows predict creation of industrial plasma installations, adapted to conditions of various terrorist threats, with minimized power consumption and optimized technological parameters

Aqueous media treatment and decontamination of hazardous chemical and biological substances by contact plasma

Energy Technology Data Exchange (ETDEWEB)

Pivovarov, A; Kravchenko, A [Ukrainian State University of Chemical Engineering, Dnepropetrovsk (Ukraine); Kublanovsky, V [V. I. Vernadsky Institute of General and Inorganic Chemistry of National Academy of Science, Kiev (Ukraine)

2009-07-01

Usage of non-equilibrium contact plasma for processes of decontamination and neutralization in conditions of manifestation of chemical, biological and radiation terrorism takes on special significance due to portability of equipment and its mobility in places where toxic liquid media hazardous for people's health are located. Processes of decontamination of aqueous media, seminated with pathogenic microorganisms and viruses, treatment of water containing toxic heavy metals, cyanides, surface-active substances, and heavy radioactive elements, are investigated. Examples of activation processes in infected water and toxic aqueous solutions present convincing evidence of the way, how new quality technological approach for achievement of high enough degree of the said media treatment is used in each specific case. Among new properties of water activated as a result of action of non-equilibrium contact plasma, it is necessary to mention presence of cluster structure, confirmed by well-known spectral and physical-chemical methods, presence of peroxide compounds, active particles and radicals. Anti-microbial activity which is displayed under action of plasma in aqueous media (chemically pure water, drinking water, aqueous solutions of sodium chloride, potassium iodide, as well as other inorganic compounds) towards wide range of pathogenic and conventionally pathogenic microorganisms allows use them as reliable, accessible and low-cost preparations for increasing the degree of safety of food products. Combination of such processes with known methods of filtration and ultra-filtration gives an efficient and available complex capable of withstanding any threats, which may arise for population and living organisms. Present-day level of machine-building, electrical engineering, and electronics allows predict creation of industrial plasma installations, adapted to conditions of various terrorist threats, with minimized power consumption and optimized technological parameters

EFSA BIOHAZ Panel (EFSA Panel on Biological Hazards), 2013. Scientific Opinion on the public health hazards to be covered by inspection of meat from farmed game

DEFF Research Database (Denmark)

Hald, Tine; Baggesen, Dorte Lau

ranked as medium or lower potential concern. More effective control of biological hazards could be achieved using an integrated farm to chilled carcass approach, including improved food chain information (FCI) and risk-based controls. Further studies are required on Salmonella spp. in farmed wild boar...... and T. gondii in farmed wild boar and farmed deer. If new information confirms a high risk to public health from meat from these species, setting targets at carcass level should be considered. Palpation and incision should be omitted, as it will not detect biological hazards considered to be a high......Salmonella spp. in farmed wild boar and Toxoplasma gondii in farmed deer and farmed wild boar were ranked as a high priority for meat inspection. Trichinella spp. in wild boar was ranked as low priority due to current controls, which should be continued. For chemical hazards, all substances were...

Environmental effects and potential hazards of chemical substances used in waste water purification; Umweltvertraeglichkeit und Gefaehrdungspotentiale von Abwasserbehandlungschemikalien

Energy Technology Data Exchange (ETDEWEB)

Schumann, H. [Umweltbundesamt, Berlin (Germany). Inst. fuer Wasser-, Boden- und Lufthygiene

1999-07-01

Waste water purification in sewage systems would be impossible without additions of chemical substances for coagulation, flocculation and neutralisation. However, these substances also pollute the purified waste water and the freshwater supplies. In addition, the non-reactive fraction of toxic substances originally contained in the waste water is discharged with the purified waste water and adds to the pollution of freshwater reservoirs. Detailed investigations are required for defining the state of the art in the use of chemical substances for waste water purification. [German] Um Schadstoffe aus dem Abwasser zu entfernen, werden in der Klaeranlage bestimmte Hilfsstoffe zugesetzt, ohne die eine Reinigung des Abwassers nicht in dieser Qualitaet moeglich waere und unverhaeltnismaessig teuer wuerde. Die Hilfsstoffe unterstuetzen den Reinigungsprozess durch Faellung, Flockung und Neutralisation. Durch den Einsatz dieser Chemikalien zur Behandlung von Abwaessern gelangen jedoch auch - Verunreinigungen durch die Nebenstoff-Matrix der eingesetzten Behandlungschemikalien in das behandelte Abwasser und in die Gewaesser und - durch ueberstoechiometrische Dosierung oder Additive tritt der nicht reagierende Teil toxischer Substanzen ebenfalls im behandelten Abwasserablauf und im Gewaesser auf. Detaillierte Untersuchungen erscheinen geboten, um auf dieser Grundlage den Stand der Technik beim Einsatz von Chemikalien zur Abwasserbehandlung zu formulieren. (orig./SR)

Delisting efforts for mixed radioactive and chemically hazardous waste at the Oak Ridge Gaseous Diffusion Plant

International Nuclear Information System (INIS)

Goodpasture, S.T.

1987-01-01

Presently, there are four hazardous wastes at the Oak Ridge Gaseous Diffusion Plant that are candidates for the delisting from the Resource Conservation and Recovery Act (RCRA) hazardous waste regulations. These candidates are the sludges from K-1407-B and C ponds, Central Neutralization Facility sludges, mixed sludges from Y-12 and the ash generated by the RCRA/Toxic Substances Control Act (TSCA) Incinerator. All of these hazardous wastes contain radioactive constituents as well as hazardous constituents. The delisting will be based upon the nonradioactive constituents. Whether the delisting petition is granted or not, the wastes will be handled according to the Department of Energy guidelines for radioactive wastes. The presentation discusses the methodologies for delisting these wastes and the rationale behind the processes

Teenagers' Awareness of Peers' Substance and Drug Use in Kuwait.

Science.gov (United States)

Omu, Florence E; Bader, Al-Wadaany; Helen, Delles; Slabeeb, Shukriya; Safar, Hanan; Omu, Alexander E

Teenage substance use is a global challenge, and youths residing in Kuwait are not immune from it. Tobacco products are licit; however, alcohol and other mood-altering illicit substance are prohibited with severe penalties including imprisonment. Youths residing in Kuwait are being initiated into the use of mood-altering substances like tobacco at an early age, and it is postulated that, as they grow older, they may progress into using alcohol and other prohibited illicit drugs. The aim of this study was to determine licit and illicit substance use by teenagers residing in Kuwait. The study will also explore their awareness of substance use among their peers. A cross-sectional survey using a snowball sampling technique was used to recruit 190 teenagers aged 15-18 years residing in Kuwait. Data were collected using the 130-item questionnaire adapted from 1998 New Jersey Triennial Public High School Survey of Drug and Alcohol Use. Data collection was from September 2012 to June 2013. The Statistical Package for Social Sciences Version 22 for Windows was used. Pearson's chi-square, Kruskal-Wallis, and Mann-Whitney U tests were used to test the hypotheses. Tobacco was the most commonly used substance by these teenagers; 8.4% were current smokers, and 50% had experimented. Age of initiation for 21% was before 14 years old. Hashish (marijuana) was the most commonly used illicit drug, with 3.7% current users and 5.3% claiming to have used it. More male than female teenagers in Grade 9 were using tobacco products (χ = 27.428, df = 5, p abuse of mood/mind-altering licit and illicit substances appear to be increasing among older teenagers. Intensifying campaigns about the hazards of substance use and drug testing should start from the primary school level.

Hazard Assessment on Chlorine Distribution Use of Chemical Transportation Risk Index

International Nuclear Information System (INIS)

Kim, Jeong Gon; Byun, Hun Soo

2014-01-01

Chlorine is one of the most produced and most used non-flammable chemical substances in the world even though its toxicity and high reactivity cause the ozone layer depletion. However, in modern life, it is impossible to live a good life without using Chlorine and its derivatives since they are being used as an typical ingredient in more than 40 percent of the manufactured goods including medicines, detergents, deodorant, fungicides, herbicides, insecticides, and plastic, etc. Even if Chlorine has been handled and distributed in various business (small and medium-sized businesses, water purification plants, distribution company, etc.), there have been few researches about its possible health hazard and transportation risks. Accordingly, the purpose of this paper is to make a detailed assessment of Chlorinerelated risks and to model an index of chemicals transportation risks that is adequate for domestic circumstances. The assessment of possible health hazard and transportation risks was made on 13 kinds of hazardous chemicals, including liquid chlorine. This research may be contributed to standardizing the risk assessment of Chlorine and other hazardous chemicals by using an index of transportation risks

Hazard Assessment on Chlorine Distribution Use of Chemical Transportation Risk Index

Energy Technology Data Exchange (ETDEWEB)

Kim, Jeong Gon [Hanwha Chemical Ulsan Site, Ulsan (Korea, Republic of); Byun, Hun Soo [Chonnam National University, Yeosu (Korea, Republic of)

2014-12-15

Chlorine is one of the most produced and most used non-flammable chemical substances in the world even though its toxicity and high reactivity cause the ozone layer depletion. However, in modern life, it is impossible to live a good life without using Chlorine and its derivatives since they are being used as an typical ingredient in more than 40 percent of the manufactured goods including medicines, detergents, deodorant, fungicides, herbicides, insecticides, and plastic, etc. Even if Chlorine has been handled and distributed in various business (small and medium-sized businesses, water purification plants, distribution company, etc.), there have been few researches about its possible health hazard and transportation risks. Accordingly, the purpose of this paper is to make a detailed assessment of Chlorinerelated risks and to model an index of chemicals transportation risks that is adequate for domestic circumstances. The assessment of possible health hazard and transportation risks was made on 13 kinds of hazardous chemicals, including liquid chlorine. This research may be contributed to standardizing the risk assessment of Chlorine and other hazardous chemicals by using an index of transportation risks.

Assessment of existing and produced substances according to Annex II of the 12th Federal Emission Control Ordinance (BImSchV) for installations for the burning of fine ceramics

International Nuclear Information System (INIS)

Goessl, M.; Mair, K.

1990-01-01

Substances in the installations for burning fine ceramics, using natural gas or light fuel oil, and substances produced during disturbed operations, e.g. during a fire in a storage facility for light fuel oil, obviously do not present a general hazard. During storage of the fuels butane and propane, quantity level A is always, and quantity level B as a rule not reached. A general hazard within the meaning of the Accident Ordinance thus cannot be excluded in principle. (orig.) [de

Early substance consumption and problematic use of video games in adolescence

Science.gov (United States)

Coëffec, Adélaïde; Romo, Lucia; Cheze, Nathalie; Riazuelo, Hélène; Plantey, Sophie; Kotbagi, Gayatri; Kern, Laurence

2015-01-01

Substance use as well as use of video games is frequent among young people. The purpose of this research was to study the links between the use of video games and the consumption of various substances such as alcohol, tobacco or cannabis at adolescence. In order to do so, 1423 students from middle and high schools filled an auto-questionnaire that included questions on age, gender, year of study, use of video games and consumptions of alcohol (Alcohol Use Disorders Identification Test Short version, AUDIT-C), tobacco (Heaviness of Smoking Index, HSI), and cannabis (Cannabis Abuse Screening Test, CAST). We found that 92.1% of teens use video games and 17.7% have a problematic use of video games (PUVG). Furthermore, results show that substance consumption seems frequent with 19.8 and 8.3% of participants having hazardous alcohol and cannabis consumptions respectively and 5.2% having a moderate to high tobacco dependence. Video gamers consumed significantly more alcohol and gamers with PUVG started their substance consumption (alcohol, tobacco, and cannabis) earlier. PUVG was found to be negatively correlated to age at first substance consumption, but positively correlated to the time spent playing video games. However, it was not correlated to risks of substance dependence (scores of AUDIT-C, HSI, and CAST). Finally, our results are consistent with the literature, in regard to frequency of substance use and use of video games in adolescence. These data will allow for a better consideration of prevention strategies and future care in this particular field. PMID:25972826

Early substance consumption and problematic use of video games in adolescence.

Science.gov (United States)

Coëffec, Adélaïde; Romo, Lucia; Cheze, Nathalie; Riazuelo, Hélène; Plantey, Sophie; Kotbagi, Gayatri; Kern, Laurence

2015-01-01

Substance use as well as use of video games is frequent among young people. The purpose of this research was to study the links between the use of video games and the consumption of various substances such as alcohol, tobacco or cannabis at adolescence. In order to do so, 1423 students from middle and high schools filled an auto-questionnaire that included questions on age, gender, year of study, use of video games and consumptions of alcohol (Alcohol Use Disorders Identification Test Short version, AUDIT-C), tobacco (Heaviness of Smoking Index, HSI), and cannabis (Cannabis Abuse Screening Test, CAST). We found that 92.1% of teens use video games and 17.7% have a problematic use of video games (PUVG). Furthermore, results show that substance consumption seems frequent with 19.8 and 8.3% of participants having hazardous alcohol and cannabis consumptions respectively and 5.2% having a moderate to high tobacco dependence. Video gamers consumed significantly more alcohol and gamers with PUVG started their substance consumption (alcohol, tobacco, and cannabis) earlier. PUVG was found to be negatively correlated to age at first substance consumption, but positively correlated to the time spent playing video games. However, it was not correlated to risks of substance dependence (scores of AUDIT-C, HSI, and CAST). Finally, our results are consistent with the literature, in regard to frequency of substance use and use of video games in adolescence. These data will allow for a better consideration of prevention strategies and future care in this particular field.

75 FR 34405 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2010-06-17

..., Colorado. RMA was established in 1942 by the U.S. Army to manufacture chemical warfare agents and... liquids and decontamination waters (1995). OU 26: Chemical Process-Related Activities IRA--Decontamination... Ordnance/Explosives and Recovered Chemical Warfare Materiel Hazards at the Rocky Mountain Arsenal...

Records, record linkage, and the identification of long term environmental hazards

Energy Technology Data Exchange (ETDEWEB)

Acheson, E. D.

1978-11-15

Long-term effects of toxic substances in man which have been recognized so far have been noticed because they have involved gross relative risks, or bizarre effects, or have been stumbled upon by chance or because of special circumstances. These facts and some recent epidemiological evidence together suggest that a systematic approach with more precise methods and data would almost certainly reveal the effects of many more toxic substances, particularly in workers exposed in manufacturing industry. Additional ways are suggested in which record linkage techniques might be used to identify substances with long-term toxic effects. Obstacles to further progress in the field of monitoring for long-term hazards in man are: lack of a public policy dealing with confidentiality and informed consent in the use of identifiable personal records, which balances the needs of bona fide research workers with proper safeguards for the privacy of the individual, and lack of resources to improve the quality, accessibility and organization of the appropriate data. (PCS)

A comparative survey of chemistry-driven in silico methods to identify hazardous substances under REACH

NARCIS (Netherlands)

Nendza, M.; Gabbert, S.G.M.; Kühne, R.; Lombardo, A.; Roncaglioni, A.; Benfenati, E.; Benigi, R.; Bossa, C.; Strempel, S.; Scheringer, M.; Fernandez, A.; Rallo, R.; Giralt, F.; Dimitrov, S.; Mekenyan, O.; Bringezu, F.; Schüürmann, G.

2013-01-01

This paper presents an inventory of in silico screening tools to identify substance properties of concern under the European chemicals’ legislation REACH. The objective is to support the selection and implementation of appropriate tools as building blocks within integrated testing strategies (ITS).

Written instructions for the transport of hazardous materials: Accident management instruction sheets

International Nuclear Information System (INIS)

Ridder, K.

1988-01-01

In spite of the regulations and the safety provisions taken, accidents are not entirely avoidable in the transport of hazardous materials. For managing an accident and preventing further hazards after release of dangerous substances, the vehicle drivers must carry with them the accident management instruction sheets, which give instructions on immediate counter measures to be taken by the driver, and on information to be given to the police and the fire brigades. The article in hand discusses the purpose, the contents, and practice-based improvement of this collection of instruction sheets. Particular reference is given to the newly revised version of June 15, 1988 (Verkehrsblatt 1/88) of the 'Directives for setting up accident management instruction sheets - written instructions - for road transport of hazardous materials', as issued by the Federal Ministry of Transport. (orig./HP) [de

Management of risk factors in the selection and use of PPE [personal protective equipment] on hazardous waste sites

International Nuclear Information System (INIS)

Kemplin, M.G.

1988-01-01

Industrial hygiene managers working in the hazardous waste area face daily decisions concerning appropriate levels of personal protective equipment (PPE) for hazards expected on various waste site projects. Typical hazards include exposures to toxic dust, chemical vapors, toxic gases, splashes of corrosive or toxic substances, radioactive materials and high noise levels. Managers who are experienced in this area recognize that each item of PPE can represent potential hazards in its own right. For example, full-face respirators typically restrict peripheral vision and can impede proper communications. In high ambient temperature conditions, coated protective suits can represent significant heat stress concerns, etc. Accordingly, this paper reviews health and safety management decision-making in this regard

Hazardous Health Behaviour among Medical Students: a Study from Turkey.

Science.gov (United States)

Nacar, Melis; Cetinkaya, Fevziye; Baykan, Zeynep; Yilmazel, Gulay; Elmali, Ferhan

2015-01-01

Hazardous health behaviour in young people is an important factor that affects the individual risk for non-communicable diseases and other disorders later in life. This study aimed to determine the hazardous health behaviour of first and last class medical students of Erciyes University. This descriptive study was carried out with 240 medical students from the first and 130 students from the last (sixth) class. Data were obtained by questionnaire between March-April 2012. In total, 339 students were included with a response rate of 91.6%. Socio-demographic characteristics, school success, self-reported economic difficulties, health perceptions, hazardous health behaviour related to chronic disease, tobacco, alcohol, substance use, body weight, height, traffic, violence and nutrition were assessed in line with the literature. Of the participants; 64.0% were from first and 36.0% were from the last class. Mean ages for the first and last classes were 19.4 ± 1.5 and 24.0 ± 1.5 years, respectively. In the current study, males exhibited more hazardous behaviour than females. Sime 19.8% of the students in the study group used alcohol, 35.4% used a waterpipe, and 24.8% used tobacco at least once. These rates increased in both genders in the last class and the increase in males was significant. Some 3.8% of the students in the current study used pleasure-inducing illegal substances at least once. All the students participating in the current study were single, the number of males reported not using condoms (8.6%) was 4.56 times higher compared to females. Some 64.0% of the students did not perform physical activity lasting at least 30 minutes for five times a week, 13.0% did not sleep for mean 7-8 hours daily, males having a 2.9 times higher risk. More than 1/3 of the students did not consume cooked vegetable dishes and 1/4 did not consume fresh fruits and salads, the rates were higher among males. In the current study, hazardous health behaviour was prevalent among

Longitudinal dispersion of radioactive substances in Federal waterways

Energy Technology Data Exchange (ETDEWEB)

Krause, W.J. [Bundesanstalt fuer Gewaesserkunde (BfG), Koblenz (Germany); Speer, W.; Luellwitz, T.; Cremer, M.; Tolksdorf, W.

2007-08-15

In the context of radioactivity monitoring in German Federal Waterways (BWStr) by the Federal Institute of Hydrology (BfG) according to the Precautionary Radiation Protection Act (StrVG), the prediction of the dispersion of radioactive substances in water is one of the key tasks. The aim is the forecasting of the longitudinal dispersion of concentrations of soluble hazardous substances in flowing water. These predictions are based on the so-called dispersion tests with tritium as a tracer that the BfG has performed since 1980. Characteristic parameters like discharge-dependent flow velocities, dispersion and elimination constants related to emission sources or selected river sections are determined. They will serve as basis for a mathematical model to forecast discharge-dependent flow velocities, expected impact times, concentration maxima, and the duration of critical increases in concentrations. In the following, the results obtained till now from three investigation campaigns on the River Weser and its source rivers Werra and Fulda are described. (orig.)

78 FR 48809 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

Science.gov (United States)

2013-08-12

... liquid hazardous waste, which included industrial and plating sludge, caustics, acid solutions, oil... performance objectives. Source control focuses on preventing surface water from infiltrating the waste unit... located just to the west of the Site. Waste management of Oklahoma (WMO) is the current owner of the MRSL...

Predictors of Dropout From Inpatient Substance Use Treatment: A Prospective Cohort Study.

Science.gov (United States)

Andersson, Helle Wessel; Steinsbekk, Aslak; Walderhaug, Espen; Otterholt, Eli; Nordfjærn, Trond

2018-01-01

Dropout from inpatient treatment for substance use disorder (SUD) is an ongoing challenge. The aim of this study was to identify demographic, substance use, and psychological factors that predict dropout from postdetoxification inpatient SUD treatment. A total of 454 patients from 5 inpatient SUD centers in Central Norway were consecutively included in this naturalistic, prospective cohort study. A total of 132 patients (28%) did not complete the planned treatment stay (dropped out). Cox regression analysis showed that higher levels of intrinsic motivation for changing personal substance use reduced the dropout risk (adjusted hazard ratio [adjHR]: 0.62, 95% confidence interval [CI]: 0.48-0.79). Higher levels of mental distress were associated with an increased risk for dropout (adjHR: 1.48, 95% CI: 1.11-1.97). The role of mental health and motivation in reducing dropout risk from inpatient SUD treatment should be targeted in future prospective intervention studies.

Predictors of Dropout From Inpatient Substance Use Treatment: A Prospective Cohort Study

Science.gov (United States)

Andersson, Helle Wessel; Steinsbekk, Aslak; Walderhaug, Espen; Otterholt, Eli; Nordfjærn, Trond

2018-01-01

Introduction: Dropout from inpatient treatment for substance use disorder (SUD) is an ongoing challenge. The aim of this study was to identify demographic, substance use, and psychological factors that predict dropout from postdetoxification inpatient SUD treatment. Materials and methods: A total of 454 patients from 5 inpatient SUD centers in Central Norway were consecutively included in this naturalistic, prospective cohort study. Results: A total of 132 patients (28%) did not complete the planned treatment stay (dropped out). Cox regression analysis showed that higher levels of intrinsic motivation for changing personal substance use reduced the dropout risk (adjusted hazard ratio [adjHR]: 0.62, 95% confidence interval [CI]: 0.48-0.79). Higher levels of mental distress were associated with an increased risk for dropout (adjHR: 1.48, 95% CI: 1.11-1.97). Conclusions: The role of mental health and motivation in reducing dropout risk from inpatient SUD treatment should be targeted in future prospective intervention studies. PMID:29531472

Predictors of Dropout From Inpatient Substance Use Treatment: A Prospective Cohort Study

Directory of Open Access Journals (Sweden)

Helle Wessel Andersson

2018-02-01

Full Text Available Introduction: Dropout from inpatient treatment for substance use disorder (SUD is an ongoing challenge. The aim of this study was to identify demographic, substance use, and psychological factors that predict dropout from postdetoxification inpatient SUD treatment. Materials and methods: A total of 454 patients from 5 inpatient SUD centers in Central Norway were consecutively included in this naturalistic, prospective cohort study. Results: A total of 132 patients (28% did not complete the planned treatment stay (dropped out. Cox regression analysis showed that higher levels of intrinsic motivation for changing personal substance use reduced the dropout risk (adjusted hazard ratio [adjHR]: 0.62, 95% confidence interval [CI]: 0.48-0.79. Higher levels of mental distress were associated with an increased risk for dropout (adjHR: 1.48, 95% CI: 1.11-1.97. Conclusions: The role of mental health and motivation in reducing dropout risk from inpatient SUD treatment should be targeted in future prospective intervention studies.

Industrial Accidents Triggered by Natural Hazards: an Emerging Risk Issue

Science.gov (United States)

Renni, Elisabetta; Krausmann, Elisabeth; Basco, Anna; Salzano, Ernesto; Cozzani, Valerio

2010-05-01

Natural disasters such as earthquakes, tsunamis, flooding or hurricanes have recently and dramatically hit several countries worldwide. Both direct and indirect consequences involved the population, causing on the one hand a high number of fatalities and on the other hand so relevant economical losses that the national gross product may be affected for many years. Loss of critical industrial infrastructures (electricity generation and distribution, gas pipelines, oil refineries, etc.) also occurred, causing further indirect damage to the population. In several cases, accident scenarios with large releases of hazardous materials were triggered by these natural events, causing so-called "Natech events", in which the overall damage resulted from the simultaneous consequences of the natural event and of the release of hazardous substances. Toxic releases, large fires and explosions, as well as possible long-term environmental pollution, economical losses, and overloading of emergency systems were recognised by post-event studies as the main issues of these Natech scenarios. In recent years the increasing frequency and severity of some natural hazards due to climate change has slowly increased the awareness of Natech risk as an emerging risk among the stakeholders. Indeed, the iNTeg-Risk project, co-funded by the European Commission within the 7th Framework Program specifically addresses these scenarios among new technological issues on public safety. The present study, in part carried out within the iNTeg-Risk project, was aimed at the analysis and further development of methods and tools for the assessment and mitigation of Natech accidents. Available tools and knowledge gaps in the assessment of Natech scenarios were highlighted. The analysis mainly addressed the potential impact of flood, lightning and earthquake events on industrial installations where hazardous substances are present. Preliminary screening methodologies and more detailed methods based on

Lessons learned from the EG&G consolidated hazardous waste subcontract and ESH&Q liability assessment process

Energy Technology Data Exchange (ETDEWEB)

Fix, N.J.

1995-03-01

Hazardous waste transportation, treatment, recycling, and disposal contracts were first consolidated at the Idaho National Engineering Laboratory in 1992 by EG&G Idaho, Inc. At that time, disposition of Resource, Conservation and Recovery Act hazardous waste, Toxic Substance Control Act waste, Comprehensive Environmental Response, Compensation, and Liability Act hazardous substances and contaminated media, and recyclable hazardous materials was consolidated under five subcontracts. The wastes were generated by five different INEL M&O contractors, under the direction of three different Department of Energy field offices. The consolidated contract reduced the number of facilities handling INEL waste from 27 to 8 qualified treatment, storage, and disposal facilities, with brokers specifically prohibited. This reduced associated transportation costs, amount and cost of contractual paperwork, and environmental liability exposure. EG&G reviewed this approach and proposed a consolidated hazardous waste subcontract be formed for the major EG&G managed DOE sites: INEL, Mound, Rocky Flats, Nevada Test Site, and 10 satellite facilities. After obtaining concurrence from DOE Headquarters, this effort began in March 1992 and was completed with the award of two master task subcontracts in October and November 1993. In addition, the effort included a team to evaluate the apparent awardee`s facilities for environment, safety, health, and quality (ESH&Q) and financial liability status. This report documents the evaluation of the process used to prepare, bid, and award the EG&G consolidated hazardous waste transportation, treatment, recycling, and/or disposal subcontracts and associated ESH&Q and financial liability assessments; document the strengths and weaknesses of the process; and propose improvements that would expedite and enhance the process for other DOE installations that used the process and for the re-bid of the consolidated subcontract, scheduled for 1997.

Environmental epidemiology, Volume 1: Public health and hazardous wastes

International Nuclear Information System (INIS)

Anon.

1991-01-01

Environmental Epidemiology, Volume 1, represents the first of several planned volumes on the uses of epidemiologic techniques to study environmental public health issues. This text focuses on environmental epidemiology as it relates to hazardous waste in the United States. This study was commissioned by the Agency for Toxic Substances and Disease Registry to examine available data for evidence of adverse health effects on human populations exposed to hazardous waste. The committee was also asked to identify data gaps which were impediments to analyzing hazardous waste health effects and to suggest ways that such environmental health assessments might be improved. The committee's solution to the paucity of data on this issue was to concentrate in this volume on identifying the available, peer-reviewed data and, consequently, the major data gaps. The study opens with a recapitulation of the context of hazardous waste sites in the United States, the approaches currently used by state and federal epidemiologists in analyzing hazardous waste exposure and effects, and candid assessment of the problems associated with environmental exposure assessment. From that context, the committee then presents the data currently available to assess human exposures through air, domestic water consumption, soil, and the food chain. The general focus here is on biomarker data as the date of choice. As with all NAS reports, this one closes with general conclusions and recommendations. Environmental health risk assessors will find this volume a valuable resource

Development of Non-hazardous Explosives for Security Training and Testing (NESTT)

International Nuclear Information System (INIS)

Kury, J.W.; Simpson, R.L.; Hallowell, S.F.

1996-01-01

The security force at the Lawrence Livermore National Laboratory (LLNL) routinely used canines to search for explosives and other contraband substances. The use of threat quantities of explosive for realistic training in populated or sensitive Laboratory areas has not been permitted because of the hazard. To overcome this limitation a series of non-hazardous materials with authentic signatures have been prepared and evaluated. A series of materials has been prepared that have authentic properties of explosives but are non-hazardous. These NESTT materials are prepared by coating a few micron thick layer of an explosive on a non-reactive substrate. This produces a formulation with an authentic vapor and molecular signature. Authentic x-ray and oxygen/nitrogen density signatures are obtained through the appropriate choice of a substrate. The signatures of NESTT TNT and NESTT Comp. C-4 have been verified by instrument and canine (K-9) detection in a Beta Test Program

Identification of sources of priority substances set out in Article 16 of the Water Framework Directive and estimation of their discharges into the German aquatic environment; Ermittlung der Quellen fuer die prioritaeren Stoffe nach Artikel 16 der Wasserrahmenrichtlinie und Abschaetzung ihrer Eintragsmengen in die Gewaesser in Deutschland

Energy Technology Data Exchange (ETDEWEB)

Boehm, E.; Hillenbrand, T.; Marscheider-Weidemann, F.; Mueller, B.; Wiederhold, J.; Herrchen, M.; Klein, M.

2002-12-01

The Water Framework Directive (2000/60/EC) is a new instrument, that inter alia has replaced, harmonized and further developed the control and reduction of point and diffuse discharges of dangerous substances according to Council Directive 76/464/EEC. Article 16 of the Water Framework Directive set out a 'Strategy against pollution of water' which demands specific measures against pollution of water by individual pollutants or groups of pollutants presenting a significant risk to or via the aquatic environment (e.g. by drinking water consumed). For these priority substances community-wide water quality standards and emission controls have to be established. On the basis of Article 16 of Directive 2000/60/EC a list of 33 priority substances has been adopted by the decision of the European Parliament and of the Council of November 2001. This list identifies 11 priority hazardous substances, 14 substances subject to a review for identification as possible priority hazardous substance and 8 priority substances. The Commission will make a proposal for the final classification of the 'substances subject to a review' (priority hazardous or priority substances) not later than 12 months after adoption of this list. The planned measures aim at the cessation or phasing out of discharges, emissions and losses to the aquatic environment within 20 years for the priority hazardous substances and at the progressive reduction for the priority substances. In this project the available data for these 33 substances resp. groups of substances for the Federal Republic of Germany were put forward and described in a standardized pattern. This pattern includes the following items: nomenclature and properties of the substances, monitoring data, production and fields of application of these substances, existing regulations in Germany, releases to environment and possibilities to reduce discharges to the aquatic environment. The basis of the data is the year 2000 as far as

Taxonomic analysis of perceived risk: modeling individual and group perceptions within homogeneous hazard domains

International Nuclear Information System (INIS)

Kraus, N.N.; Slovic, P.

1988-01-01

Previous studies of risk perception have typically focused on the mean judgments of a group of people regarding the riskiness (or safety) of a diverse set of hazardous activities, substances, and technologies. This paper reports the results of two studies that take a different path. Study 1 investigated whether models within a single technological domain were similar to previous models based on group means and diverse hazards. Study 2 created a group taxonomy of perceived risk for only one technological domain, railroads, and examined whether the structure of that taxonomy corresponded with taxonomies derived from prior studies of diverse hazards. Results from Study 1 indicated that the importance of various risk characteristics in determining perceived risk differed across individuals and across hazards, but not so much as to invalidate the results of earlier studies based on group means and diverse hazards. In Study 2, the detailed analysis of railroad hazards produced a structure that had both important similarities to, and dissimilarities from, the structure obtained in prior research with diverse hazard domains. The data also indicated that railroad hazards are really quite diverse, with some approaching nuclear reactors in their perceived seriousness. These results suggest that information about the diversity of perceptions within a single domain of hazards could provide valuable input to risk-management decisions

Hazard banding in compliance with the new Globally Harmonised System (GHS) for use in control banding tools.

Science.gov (United States)

Arnone, Mario; Koppisch, Dorothea; Smola, Thomas; Gabriel, Stefan; Verbist, Koen; Visser, Remco

2015-10-01

Many control banding tools use hazard banding in risk assessments for the occupational handling of hazardous substances. The outcome of these assessments can be combined with advice for the required risk management measures (RMMs). The Globally Harmonised System of Classification and Labelling of Chemicals (GHS) has resulted in a change in the hazard communication elements, i.e. Hazard (H) statements instead of Risk-phrases. Hazard banding schemes that depend on the old form of safety information have to be adapted to the new rules. The purpose of this publication is to outline the rationales for the assignment of hazard bands to H statements under the GHS. Based on this, this publication proposes a hazard banding scheme that uses the information from the safety data sheets as the basis for assignment. The assignment of hazard bands tiered according to the severity of the underlying hazards supports the important principle of substitution. Additionally, the set of assignment rules permits an exposure-route-specific assignment of hazard bands, which is necessary for the proposed route-specific RMMs. Ideally, all control banding tools should apply the same assignment rules. This GHS-compliant hazard banding scheme can hopefully help to establish a unified hazard banding strategy in the various control banding tools. Copyright © 2015 Elsevier Inc. All rights reserved.

A review of implicit and explicit substance self-concept as a predictor of alcohol and tobacco use and misuse.

Science.gov (United States)

Lindgren, Kristen P; Neighbors, Clayton; Gasser, Melissa L; Ramirez, Jason J; Cvencek, Dario

2017-05-01

This paper provides an overview of the self-concept as it relates to substance use. Self-concept has a long history in psychological theory and research; however, substance self-concept (e.g., viewing one's self as a drinker or smoker) is an understudied area of research with the potential to expand existing conceptualizations of substance use, addiction, and prevention and treatment efforts, and should receive greater research attention. First, we review and provide a theoretical framework of substance self-concept that draws from dual process models and distinguishes between implicit and explicit self-concept. Next, we summarize key findings related to substance use in the extant literature, focusing on alcohol and tobacco (smoking). Across both substances, there is converging evidence that substance self-concept is associated with substance use outcomes, including quantity and frequency of use and problems associated with use, and that change in substance self-concept is associated with recovery from substance misuse. Recommendations for the substance self-concept research agenda include routine assessment of substance self-concept, expanded use of implicit measures, investigation of moderators of substance self-concept, and targeting substance self-concept directly in prevention and intervention efforts. Ultimately, we suggest that substance self-concept is a promising, but understudied, construct. Greater research attention to substance self-concept could clarify its potential as an important risk factor for hazardous use and addiction as well as its utility as a prevention and treatment target.

Household hazardous waste in municipal landfills: contaminants in leachate

International Nuclear Information System (INIS)

Slack, R.J.; Gronow, J.R.; Voulvoulis, N.

2005-01-01

Household hazardous waste (HHW) includes waste from a number of household products such as paint, garden pesticides, pharmaceuticals, photographic chemicals, certain detergents, personal care products, fluorescent tubes, waste oil, heavy metal-containing batteries, wood treated with dangerous substances, waste electronic and electrical equipment and discarded CFC-containing equipment. Data on the amounts of HHW discarded are very limited and are hampered by insufficient definitions of what constitutes HHW. Consequently, the risks associated with the disposal of HHW to landfill have not been fully elucidated. This work has focused on the assessment of data concerning the presence of hazardous chemicals in leachates as evidence of the disposal of HHW in municipal landfills. Evidence is sought from a number of sources on the occurrence in landfill leachates of hazardous components (heavy metals and xenobiotic organic compounds [XOC]) from household products and the possible disposal-to-emissions pathways occurring within landfills. This review demonstrates that a broad range of xenobiotic compounds occurring in leachate can be linked to HHW but further work is required to assess whether such compounds pose a risk to the environment and human health as a result of leakage/seepage or through treatment and discharge

Frequency of damage by external hazards based on geographical information

Energy Technology Data Exchange (ETDEWEB)

Becker, G. [RISA Sicherheitsanalysen GmbH, Berlin (Germany); Camarinopoulos, A.; Karali, T. [ERRA, Athens (Greece); Camarinopoulos, L. [Piraeus Univ. (Greece); Schubert, B. [VENE, Hamburg (Germany)

2013-07-01

External explosions can significantly contribute to risk of damage for industrial plants. External explosions may origin from other plants in the neighborhood, which store and operate with explosive substances, or from transport of such substances on road, rail, or water. In all cases, some accident is a necessary condition for a hazard. Another probabilistic element is the probability of ignition. If transport causes the explosion, the location of the accident will influence the consequences. If deflagration is involved, ignition will not necessarily occur at the place of the accident, but a cloud of a combustible gas-air mixture may develop, which will ignite at some distance depending on wind velocity. In order to avoid unnecessarily pessimistic approaches, geographical information can be used in addition to local weather statistics. Geographical information systems provide map material for sites, roads, rail and rivers on a computer. This information can be used to find frequencies of damage based on numerical integration or on Monte Carlo simulation. A probabilistic model has been developed. It is based on: - A joint probability density function for wind direction and wind speed, which has been estimated from local weather statistics, - Frequency of hazards for neighboring plants and various types of traffic, - Statistics on the amounts and types of explosive materials, - The model has been implemented using one numerical integrations method and two variants of Monte Carlo method. Data has been collected and applied for a nuclear power plant in Northern Germany as an example. The method, however, can be used for any type of plant subject to external explosion hazards. In its present form, it makes use of design criteria specific for nuclear power plants, but these could be replaced by different criteria. (orig.)

Frequency of damage by external hazards based on geographical information

International Nuclear Information System (INIS)

Becker, G.; Camarinopoulos, A.; Karali, T.; Camarinopoulos, L.; Schubert, B.

2013-01-01

External explosions can significantly contribute to risk of damage for industrial plants. External explosions may origin from other plants in the neighborhood, which store and operate with explosive substances, or from transport of such substances on road, rail, or water. In all cases, some accident is a necessary condition for a hazard. Another probabilistic element is the probability of ignition. If transport causes the explosion, the location of the accident will influence the consequences. If deflagration is involved, ignition will not necessarily occur at the place of the accident, but a cloud of a combustible gas-air mixture may develop, which will ignite at some distance depending on wind velocity. In order to avoid unnecessarily pessimistic approaches, geographical information can be used in addition to local weather statistics. Geographical information systems provide map material for sites, roads, rail and rivers on a computer. This information can be used to find frequencies of damage based on numerical integration or on Monte Carlo simulation. A probabilistic model has been developed. It is based on: - A joint probability density function for wind direction and wind speed, which has been estimated from local weather statistics, - Frequency of hazards for neighboring plants and various types of traffic, - Statistics on the amounts and types of explosive materials, - The model has been implemented using one numerical integrations method and two variants of Monte Carlo method. Data has been collected and applied for a nuclear power plant in Northern Germany as an example. The method, however, can be used for any type of plant subject to external explosion hazards. In its present form, it makes use of design criteria specific for nuclear power plants, but these could be replaced by different criteria. (orig.)

40 CFR 63.63 - Deletion of ethylene glycol monobutyl ether from the list of hazardous air pollutants.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 9 2010-07-01 2010-07-01 false Deletion of ethylene glycol monobutyl... Quantity Designations, Source Category List § 63.63 Deletion of ethylene glycol monobutyl ether from the list of hazardous air pollutants. The substance ethylene glycol monobutyl ether (EGBE,2-Butoxyethanol...

The role of the parent in adolescent substance use.

Science.gov (United States)

Williams, Janet F; Burton, Rosalinda Strano; Warzinski, Suyen Schneegans

2014-10-01

The overall goal of adolescent development is personal emancipation through individuation. The parent is considered an adolescent's most powerful formative influence and role model regarding health attitudes, behavioral norms, and social boundaries. For adolescents, engaging in risk-taking behaviors can be a normal maturational "rewarding" response or a strategy to cope with perceived stress and express emotions. Effective stress management is an important skill set for the developing adolescent who may experiment with a range of unhealthy strategies for coping or personal expression despite their high potential for hazardous consequences. Parenting the adolescent poses the immense challenge of promoting the adolescent's development of life skills while enabling stimulating healthy opportunities during a time of increased access and vulnerability to risky choices, including substance use. Effective parenting includes consistency, communication, respect and safety-based boundaries as well as monitoring the adolescents' friends and activities, particularly media use. Not only are parents important in deterring, suspecting, and at times detecting their adolescents' substance use, they can facilitate the evaluation or interventions that may be needed to stop substance use, start recovery, and sustain it. The role of parents is to guide adolescents in developing strengths and resilience, and fulfilling their fullest life potential. Copyright 2014, SLACK Incorporated.

Experiences from the exercise ''MERLIN'' for the detection of radioactive substances with the participation of special-purpose vehicles; Erfahrungen aus der Uebung ''MERLIN'' zur Detektion radioaktiver Stoffe unter Beteiligung verschiedenen Einsatzfahrzeuge

Energy Technology Data Exchange (ETDEWEB)

Griesbach, M. [Hessisches Ministerium des Innern und fuer Sport, Wiesbaden (Germany)

2009-08-15

Experiences of an exercise with hazardous goods, in particular with radioactive substances (measurements and taking environmental samples) are described. Several special-purpose vehicles with equipment and specially trained crews were used together with radiation protection experts according to the concept of Hesse. It has been the greatest exercise in Hesse with regard to hazardous goods and in particular with regard to ''incidents with radioactive substances''. (orig.)

Social networks, substance use, and mental health in college students.

Science.gov (United States)

Mason, Michael J; Zaharakis, Nikola; Benotsch, Eric G

2014-01-01

The relationship between social network risk (alcohol-using close friends), perceived peer closeness, substance use, and psychiatric symptoms was examined to identify risk and protective features of college students' social context. Six hundred and seventy undergraduate students enrolled in a large southeastern university. An online survey was administered to consenting students. Students with risky networks were at a 10-fold increase of hazardous drinking, 6-fold increase for weekly marijuana use, and 3-fold increase for weekly tobacco use. College students' who feel very close to their peers were protected against psychiatric symptoms yet were at increased risk for marijuana use. Perceived closeness of peers was highly protective against psychiatric symptoms, adding a natural preventive effect for a population at great risk for mental illness. RESULTS support targeting college students through network-oriented preventive interventions to address substance use as well as mental health.

Bibliography of work on the heterogeneous photocatalytic removal of hazardous compounds from water and air, Update Number 2 to October 1996

Energy Technology Data Exchange (ETDEWEB)

Blake, D.M.

1997-01-01

The Solar Industrial Program has developed processes that destroy hazardous substances in or remove them from water and air. The processes of interest in this report are based on the application of heterogeneous photocatalysts, principally titanium dioxide or modifications thereof, but work on other heterogeneous catalysts is included in this compilation. This report continues bibliographies that were published in May, 1994, and October, 1995. The previous reports included 663 and 574 citations, respectively. This update contains an additional 518 references. These were published during the period from June 1995 to October 1996, or are references from prior years that were not included in the previous reports. The work generally focuses on removing hazardous contaminants from air or water to meet environmental or health regulations. This report also references work on properties of semiconductor photocatalysts and applications of photocatalytic chemistry in organic synthesis. This report follows the same organization as the previous publications. The first part provides citations for work done in a few broad categories that are generic to the process. Three tables provide references to work on specific substances. The first table lists organic compounds that are included in various lists of hazardous substances identified by the US Environmental Protection Agency (EPA). The second table lists compounds not included in those categories, but which have been treated in a photocatalytic process. The third table covers inorganic compounds that are on EPA lists of hazardous materials or that have been treated by a photocatalytic process. A short update on companies that are active in providing products or services based on photocatalytic processes is provided.

Aversion substance(s) of the rat coagulating glands

Science.gov (United States)

Gawienowski, Anthony M.; Berry, Iver J.; Kennelly, James J.

1982-01-01

The aversive substance(s) present in adult male urine were not found in castrate rat urine. Removal of the coagulating glands also resulted in a loss of the aversion compounds. The aversion substances were restored to the urine after androgen treatment of the castrate rats.

Lessons learned from the EG ampersand G consolidated hazardous waste subcontract and ESH ampersand Q liability assessment process

International Nuclear Information System (INIS)

Fix, N.J.

1995-03-01

Hazardous waste transportation, treatment, recycling, and disposal contracts were first consolidated at the Idaho National Engineering Laboratory in 1992 by EG and G Idaho, Inc. At that time, disposition of Resource, Conservation and Recovery Act hazardous waste, Toxic Substance Control Act waste, Comprehensive Environmental Response, Compensation, and Liability Act hazardous substances and contaminated media, and recyclable hazardous materials was consolidated under five subcontracts. The wastes were generated by five different INEL M and O contractors, under the direction of three different Department of Energy field offices. The consolidated contract reduced the number of facilities handling INEL waste from 27 to 8 qualified treatment, storage, and disposal facilities, with brokers specifically prohibited. This reduced associated transportation costs, amount and cost of contractual paperwork, and environmental liability exposure. EG and G reviewed this approach and proposed a consolidated hazardous waste subcontract be formed for the major EG and G managed DOE sites: INEL, Mound, Rocky Flats, Nevada Test Site, and 10 satellite facilities. After obtaining concurrence from DOE Headquarters, this effort began in March 1992 and was completed with the award of two master task subcontracts in October and November 1993. In addition, the effort included a team to evaluate the apparent awardee's facilities for environment, safety, health, and quality (ESH and Q) and financial liability status. This report documents the evaluation of the process used to prepare, bid, and award the EG and G consolidated hazardous waste transportation, treatment, recycling, and/or disposal subcontracts and associated ESH and Q and financial liability assessments; document the strengths and weaknesses of the process; and propose improvements that would expedite and enhance the process for other DOE installations that used the process and for the re-bid of the consolidated subcontract

Pattern and Trend of Substance Abuse in Eastern Rural Iran: A Household Survey in a Rural Community

Directory of Open Access Journals (Sweden)

Hasan Ziaaddini

2013-01-01

Full Text Available Introduction and Aim. Substance abuse imposes hazards on human health in all biopsychosocial aspects. Limited studies exist on epidemiology of substance abuse and its trend in rural areas. The present study aimed to compare substance abuse in one of the rural areas of southeast Iran, in a 12-year period (2000 and 2012. Design and Methods. In a household survey conducted in 2012, in Dashtkhak/Kerman, 1200 individuals above 12 years of age completed a questionnaire to determine their frequency of substance abuse. The questionnaire included the following three areas: demographic characteristics, frequency of substance abuse and ease of access to various drugs. Results. Among 900 completed questionnaires, majority of the participants (61.8% were below 30 years of age and among them 54.4% were male. Cigarette (17.0%, opium (15.7% and opium residue (9.0% were the most frequent substances abused on a daily basis. Based on the participant’s opinion, we conclude that the ease of access to cigarette, waterpipe and opium contributed to their increase in consumption compared with earlier years. Discussion and Conclusion. The steady rise in substance abuse in rural communities demands immediate attention and emergency preventive measures from policy makers.

Recommendations on chemicals management policy and legislation in the framework of the Egyptian-German twinning project on hazardous substances and waste management.

Science.gov (United States)

Wagner, Burkhard O; Aziz, Elham Refaat Abdel; Schwetje, Anja; Shouk, Fatma Abou; Koch-Jugl, Juliane; Braedt, Michael; Choudhury, Keya; Weber, Roland

2013-04-01

The sustainable management of chemicals and their associated wastes-especially legacy stockpiles-is always challenging. Developing countries face particular difficulties as they often have insufficient treatment and disposal capacity, have limited resources and many lack an appropriate and effective regulatory framework. This paper describes the objectives and the approach of the Egyptian-German Twinning Project under the European Neighbourhood Policy to improve the strategy of managing hazardous substances in the Egyptian Environmental Affairs Agency (EEAA) between November 2008 and May 2011. It also provides an introduction to the Republic of Egypt's legal and administrative system regarding chemical controls. Subsequently, options for a new chemical management strategy consistent with the recommendations of the United Nations Chemicals Conventions are proposed. The Egyptian legal and administrative system is discussed in relation to the United Nations' recommendations and current European Union legislation for the sound management of chemicals. We also discuss a strategy for the EEAA to use the existing Egyptian legal system to implement the United Nations' Globally Harmonized System of Classification and Labelling of Chemicals, the Stockholm Convention and other proposed regulatory frameworks. The analysis, the results, and the recommendations presented may be useful for other developing countries in a comparable position to Egypt aspiring to update their legislation and administration to the international standards of sound management of chemicals.

40 CFR 370.10 - Who must comply with the hazardous chemical reporting requirements of this part?

Science.gov (United States)

2010-07-01

... Hazardous Substance (EHS) is present at your facility at any one time in an amount equal to or greater than... (For purposes of this part, retail gas station means a retail facility engaged in selling gasoline and... facility engaged in selling gasoline and/or diesel fuel principally to the public, for motor vehicle use on...

Assessment of the potential human health risks from exposure to complex substances in accordance with REACH requirements. "White spirit" as a case study.

Science.gov (United States)

McKee, Richard H; Tibaldi, Rosalie; Adenuga, Moyinoluwa D; Carrillo, Juan-Carlos; Margary, Alison

2018-02-01

The European chemical control regulation (REACH) requires that data on physical/chemical, toxicological and environmental hazards be compiled. Additionally, REACH requires formal assessments to ensure that substances can be safely used for their intended purposes. For health hazard assessments, reference values (Derived No Effect levels, DNELs) are calculated from toxicology data and compared to estimated exposure levels. If the ratio of the predicted exposure level to the DNEL, i.e. the Risk Characterization Ratio (RCR), is less than 1, the risk is considered controlled; otherwise, additional Risk Management Measures (RMM) must be applied. These requirements pose particular challenges for complex substances. Herein, "white spirit", a complex hydrocarbon solvent, is used as an example to illustrate how these procedures were applied. Hydrocarbon solvents were divided into categories of similar substances. Representative substances were identified for DNEL determinations. Adjustment factors were applied to the no effect levels to calculate the DNELs. Exposure assessments utilized a standardized set of generic exposure scenarios (GES) which incorporated exposure predictions for solvent handling activities. Computer-based tools were developed to automate RCR calculations and identify appropriate RMMs, allowing consistent communications to users via safety data sheets. Copyright © 2017 ExxonMobil Biomedical Sciences Inc. Published by Elsevier Inc. All rights reserved.

Definition of Substance and Non-substance Addiction.

Science.gov (United States)

Zou, Zhiling; Wang, Huijun; d'Oleire Uquillas, Federico; Wang, Xiaomei; Ding, Jianrui; Chen, Hong

2017-01-01

Substance addiction (or drug addiction) is a neuropsychiatric disorder characterized by a recurring desire to continue taking the drug despite harmful consequences. Non-substance addiction (or behavioral addiction) covers pathological gambling, food addiction, internet addiction, and mobile phone addiction. Their definition is similar to drug addiction but they differ from each other in specific domains. This review aims to provide a brief overview of past and current definitions of substance and non-substance addiction, and also touches on the topic of diagnosing drug addiction and non-drug addiction, ultimately aiming to further the understanding of the key concepts needed for a foundation to study the biological and psychological underpinnings of addiction disorders.

Racial/ethnic differences in unmet needs for mental health and substance use treatment in a community-based sample of sexual minority women.

Science.gov (United States)

Jeong, Yoo Mi; Veldhuis, Cindy B; Aranda, Frances; Hughes, Tonda L

2016-12-01

To examine the unmet needs for mental health and substance use treatment among a diverse sample of sexual minority women (lesbian, bisexual). Sexual minority women are more likely than heterosexual women to report depression and hazardous drinking. However, relatively little is known about sexual minority women's use of mental health or substance use treatment services, particularly about whether use varies by race/ethnicity. Cross-sectional analysis of existing data. Analyses included data from 699 Latina, African American and white sexual minority women interviewed in wave 3 of the 17-year Chicago Health and Life Experiences of Women study. Using logistic regression, we examined the associations among sexual identity, race/ethnicity, use of mental health and substance use treatment, as well as potential unmet need for treatment. Overall, women in the study reported high levels of depression and alcohol dependence, and these varied by sexual identity and race/ethnicity. Use of mental health and substance use treatment also varied by race/ethnicity, as did potential unmet need for both mental health and substance use treatment. Our findings that suggest although use of treatment among sexual minority women is high overall, there is a potentially sizable unmet need for mental health and substance use treatment that varies by race/ethnicity, with Latina women showing the greatest unmet need for treatment. Nurses and other healthcare providers should be aware of the high rates of depression and hazardous drinking among sexual minority women, understand the factors that may increase the risk of these conditions among sexual minority women, the potentially high unmet need for mental health and substance use treatment - perhaps particularly among Latina women and be equipped to provide culturally sensitive care or refer to appropriate treatment services as needed. © 2016 John Wiley & Sons Ltd.

A five-year history of hazardous materials incidents in Chester County, PA

International Nuclear Information System (INIS)

Shorten, C.V.; McNamara, J.

1993-01-01

The Emergency Planning and Community Right-to-Know Act (EPCRA) of 1986 established Local Emergency Planning Committees (LEPCs) to oversee emergency response planning at the community level. In Pennsylvania, each county was assigned its own LEPC, and Chester County held its first LEPC meeting on October 15, 1987. From the data of that meeting through September 1992, 300 hazardous materials incidents have been reported. The majority of these incidents were met with fire department response, but several warranted response by hazardous materials teams. This report presents an analysis of the database of reported hazardous materials incidents in Chester County, including chemical identification, amount released, type of response, location, and trends. Over 235 of the reported spills were either gasoline, diesel fuel, home heating oil, or kerosene, often in five to 50 gallon amounts from transportation accidents. A number of extremely hazardous substance (EHS) incidents were reported, however, including sulfuric acid, chlorine, ammonia, phosphorus, formaldehyde, bromine, methyl mercaptan, and hydrofluoric acid. The most commonly released EHS's were ammonia and chlorine. The number of hazardous materials incidents reported in Chester County increased from only 14 in 1988 to 95 in 1991, with 67 in 1992 through September. This dramatic increase is attributable to both increased reporting and an increased number of incidents. This database clearly indicates both the success of EPCRA reporting system and the magnitude of hazardous materials incidents in this part of Pennsylvania

Guidelines for safe handling of hazardous drugs: A systematic review.

Science.gov (United States)

Bernabeu-Martínez, Mari A; Ramos Merino, Mateo; Santos Gago, Juan M; Álvarez Sabucedo, Luis M; Wanden-Berghe, Carmina; Sanz-Valero, Javier

2018-01-01

To review the scientific literature related to the safe handling of hazardous drugs (HDs). Critical analysis of works retrieved from MEDLINE, the Cochrane Library, Scopus, CINHAL, Web of Science and LILACS using the terms "Hazardous Substances", "Antineoplastic Agents" and "Cytostatic Agents", applying "Humans" and "Guidelines" as filters. Date of search: January 2017. In total, 1100 references were retrieved, and from those, 61 documents were selected based on the inclusion and exclusion criteria: 24 (39.3%) documents related to recommendations about HDs; 27 (44.3%) about antineoplastic agents, and 10 (33.3%) about other types of substances (monoclonal antibodies, gene medicine and other chemical and biological agents). In 14 (23.3%) guides, all the stages in the manipulation process involving a risk due to exposure were considered. Only one guide addressed all stages of the handling process of HDs (including stages with and without the risk of exposure). The most described stages were drug preparation (41 guides, 67.2%), staff training and/or patient education (38 guides, 62.3%), and administration (37 guides, 60.7%). No standardized informatics system was found that ensured quality management, traceability and minimization of the risks associated with these drugs. Most of the analysed guidelines limit their recommendations to the manipulation of antineoplastics. The most frequently described activities were preparation, training, and administration. It would be convenient to apply ICTs (Information and Communications Technologies) to manage processes involving HDs in a more complete and simpler fashion.

Preference conditioning in healthy individuals: correlates with hazardous drinking.

Science.gov (United States)

Balodis, Iris M; Lockwood, Kathleen P; Magrys, Sylvia A; Olmstead, Mary C

2010-06-01

Conditioned reward is a classic measure of drug-induced brain changes in animal models of addiction. The process can be examined in humans using the Conditioned Pattern Preference (CPP) task, in which participants associate nonverbal cues with reward but demonstrate low awareness of this conditioning. Previously, we reported that alcohol intoxication does not affect CPP acquisition in humans, but our data indicated that prior drug use may impact conditioning scores. To test this possibility, the current study examined the relationship between self-reported alcohol use and preference conditioning in the CPP task. Working memory was assessed during conditioning by asking participants to count the cues that appeared at each location on a computer screen. Participants (69 female and 23 male undergraduate students) completed the Alcohol Use Disorders Identification Test (AUDIT) and the Rutgers Alcohol Problem Index (RAPI) as measures of hazardous drinking. Self-reported hazardous drinking was significantly correlated with preference conditioning in that individuals who scored higher on these scales exhibited an increased preference for the reward-paired cues. In contrast, hazardous drinking did not affect working memory errors on the CPP task. These findings support evidence that repeated drug use sensitizes neural pathways mediating conditioned reward and point to a neurocognitive disposition linking substance misuse and responses to reward-paired stimuli. The relationship between hazardous drinking and conditioned reward is independent of changes in cognitive function, such as working memory.

Trace substances in landfill gases. Evaluation and meaningful analysis. Spurenstoffe in Deponiegasen. Bewertung und sinnvolle Analyse

Energy Technology Data Exchange (ETDEWEB)

Eisenmann, R [Karlsruhe Univ. (T.H.) (Germany, F.R.). Engler-Bunte-Institut

1989-06-01

Many of the innumerable substances which may occur in landfill gases are to be considered as possibly dangerous; they lead to environmental problems due to their malodour or noxious combustion products. With respect to the evaluation of the traces of substances there is great unsecurity and often extreme requirements as to volume and quality of gas analyses have to be met. Generally it can be noticed that there are hazards emanating from landfill gases, but in comparison to other risks they are not excessive. The contribution shall help to clarify questions and furnish a basis for the practice-oriented and appropriate landfill gas analytics. (orig.).

Hemoglobinopatias em trabalhadores expostos à riscos ocupacionais Hemoglobinopathies in workers exposed to occupational hazards

Directory of Open Access Journals (Sweden)

Isaac L. Silva Filho

2002-12-01

Full Text Available Hemoglobinopathies have been considered the most frequent hereditary disease in Brazilian population, constituting a Public Health problem. This paper reports on screening in workers at FIOCRUZ-RJ., exposed to some hazards factors such as, chemical substances, radiation, excessive cold and heat etc., with the objective of evaluating the impact of these factors in carriers of hemoglobinopathies, mainly in sickle cell trait (AS.

[Critical aspects of the management of "hazardous" health care workers. Consensus document].

Science.gov (United States)

Magnavita, N; Cicerone, Marina; Cirese, Vania; De Lorenzo, G; Di Giannantonios, M; Fileni, A; Goggiamani, Angela; Magnavita, Giulia; Marchi, Edda; Mazzullo, D; Monami, F; Monami, S; Puro, V; Ranalletta, Dalila; Ricciardi, G; Sacco, A; Spagnolo, A; Spagnolo, A G; Squarcione, S; Zavota, Giovanna

2006-01-01

A worker is considered to be hazardous to others when, in the course of performing a specific work task, his/her health problems (e.g., substance dependence, emotional disorders, physical disability, transmissible diseases) pose a risk for other workers' or the public's health and safety, or begins to interfere with ability to function in profession life. The presence of certain illnesses or the fact that a health care worker is impaired because of them do not necessarily imply that he, or she, is hazardous for others. Working in health care increases the probability that an impaired worker being hazardous for others. Management of hazardous workers requires new techniques and procedures, and specific policies. An interdisciplinary group of experts from medical, bioethical, legal and administrative disciplines, together with trade union and employers' representatives, is currently attempting to define a way to put prevention measures into practice in accordance with state laws and individual rights. A consensus document is presented, covering critical aspects such as: social responsibility of the employer, risk management, informed consent, non compliance, confidentiality, responsibility of workers, disclosure of risk to patients, non-discrimination, counselling and recovery of impaired workers, effectiveness of international guidelines. Occupational health professionals are obliged to adhere to ethical principles in the management of "hazardous" workers; the assessment of ethical costs and benefits for the stakeholders is the basis for appropriate decisions.

Substance Identification Information from EPA's Substance Registry

Data.gov (United States)

U.S. Environmental Protection Agency — The Substance Registry Services (SRS) is the authoritative resource for basic information about substances of interest to the U.S. EPA and its state and tribal...

Long-term effects of the Focus on Families project on substance use disorders among children of parents in methadone treatment.

Science.gov (United States)

Haggerty, Kevin P; Skinner, Martie; Fleming, Charles B; Gainey, Randy R; Catalano, Richard F

2008-12-01

This study examines the efficacy of the Focus on Families project (currently called Families Facing the Future), a preventive intervention to reduce substance use disorders among children in families with a parent in methadone treatment. One hundred and thirty families were assigned randomly to a methadone clinic treatment-as-usual control condition or treatment-as-usual plus the Focus on Families intervention between 1991 and 1993. Setting Participants were recruited from two methadone clinics in the Pacific Northwest. This study examines the development of substance use disorders among the 177 children (56.84% male) involved in the program using data from a long-term follow-up in 2005, when these participants ranged in age from 15 to 29 years. The intervention was delivered through group parent-training workshops at the methadone clinics and through individualized home-based services. The intervention taught parenting skills and skills for avoiding relapse to drug abuse. At long-term follow-up, substance use disorders were measured by the Composite International Diagnostic Interview (CIDI). Survival analyses were used to assess intervention versus control differences in the hazard of developing substance use disorders. Overall, intervention and control participants did not differ significantly in risk of developing substance use disorders. However, there was evidence of a significant difference in intervention effect by gender. There was a significant reduction in the risk of developing a substance use disorder for intervention group males compared to control group males (hazard ratio = 0.53, P = 0.03), while intervention versus control differences among females were non-significant and favored the control condition. Results from this study suggest that helping parents in recovery focus on both reducing their drug use and improving their parenting skills may have long-term effects on reducing substance use disorders among their male children. However, the overall

High-Throughput and Rapid Screening of Low-Mass Hazardous Compounds in Complex Samples.

Science.gov (United States)

Wang, Jing; Liu, Qian; Gao, Yan; Wang, Yawei; Guo, Liangqia; Jiang, Guibin

2015-07-07

Rapid screening and identification of hazardous chemicals in complex samples is of extreme importance for public safety and environmental health studies. In this work, we report a new method for high-throughput, sensitive, and rapid screening of low-mass hazardous compounds in complex media without complicated sample preparation procedures. This method is achieved based on size-selective enrichment on ordered mesoporous carbon followed by matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry analysis with graphene as a matrix. The ordered mesoporous carbon CMK-8 can exclude interferences from large molecules in complex samples (e.g., human serum, urine, and environmental water samples) and efficiently enrich a wide variety of low-mass hazardous compounds. The method can work at very low concentrations down to part per trillion (ppt) levels, and it is much faster and more facile than conventional methods. It was successfully applied to rapidly screen and identify unknown toxic substances such as perfluorochemicals in human serum samples from athletes and workers. Therefore, this method not only can sensitively detect target compounds but also can identify unknown hazardous compounds in complex media.

Determination and calculation of hazardous incident scenarios in accordance with the 3rd hazardous incident administrative instruction. Vol. 2; Ermittlung und Berechnung von Stoerfallablaufszenarien nach Massgabe der 3. Stoerfallverwaltungsvorschrift. Bd. 2: Berechnungsmethoden, aktuelle Modelle und Modellgleichungen

Energy Technology Data Exchange (ETDEWEB)

Kaiser, W; Rogazewski, P; Schindler, M [TUeV Anlagentechnik GmbH, Berlin-Schoeneberg (Germany). Unternehmensgruppe TUeV Rheinland/Berlin-Brandenburg; Acikalin, A; Albrecht, M; Lambert, M; Steinbach, J [Technische Univ. Berlin (Germany)

2000-07-01

At present there are used various of procedures, calculation methods, models and model equations for hazardous incident scenarios. The procedure on principle is varying often. This guideline explains in one main part and six appendixes the methodical procedure to select specifications and assumptions on hazardous incident scenarios and their processing. Hazardous incident scenarios lead to information on emergency preparedness planning. Both general viewpoints and possibilities are shown, how to find necessary basic assumptions on a hazardous incident scenario from information on hazardous substances, on comparable hazardous incidents and on conditions of the site and the plant. Appendixes deal with precise instructions distinguished between substance release, explosion and fire (app. 1: Assessment of source terms, app. 2: Assessment of dispersion, app. 3: Assessment of effects). Appendix 4 gives explanations to appendixes 1, 2 and 3. Appendix 5 contains a collection of 15 examples of hazardous incident scenarios, which illustrate and comment the methodical procedure. Appendix 6 describes and comments software available on German market which assists the calculating of hazardous incidents. Volume 2 determines procedures with regard to methods of calculation, current models and model equations from scientists point of view. (orig.) [German] Derzeit wird eine Vielzahl von Vorgehensweisen, Berechnungsmethoden, Modellen und Modellgleichungen fuer Stoerfallablaufszenarien verwendet. Das prinzipielle Vorgehen ist haeufig unterschiedlich. Dieser Leitfaden enthaelt in einem Hauptteil und sechs Anhaengen das methodische Vorgehen zur Auswahl von Angaben und Annahmen fuer Stoerfallablaufszenarien sowie deren Bearbeitung. Stoerfallablaufszenarien fuehren zu Angaben fuer die Gefahrenabwehrplanung. Fuer das Ableiten von Stoerfallablaufszenarien sind sowohl allgemeine Gesichtspunkte als auch Moeglichkeiten dargelegt, wie man aus Angaben zu Gefahrstoffen, zu vergleichbaren

Ministerial Order of 24 April 1964 on the approval of types of devices containing radioactive substances, made in implementation of Section 3.1 d/2 of the Royal Order of 28 February 1963 embodying the General Regulations for the Protection of the Population and Workers against the Hazards of Ionizing Radiations

International Nuclear Information System (INIS)

1964-01-01

This Order lays down that approval of devices containing radioactive substances and referred to in the Royal Order of 28 February 1963 embodying the General Regulations on Protection of the Population and Workers against the Hazards of Ionizing Radiations will only be granted if the total quantity of radioisotopes contained therein does not exceed certain values laid down by the 1963 Royal Order, and the radioactive substances are adequately shielded. It also lays down the procedure to be complied with for obtaining such approval and the conditions the applicant must meet to obtain the certificate of approval, which is valid for six years and may be renewed. The Ministry of Employment and Labour, Institute of Hygiene and Epidemiology, and the Ministry of Public Health and the Family are the competent authorities in respect of applications for a certificate of approval. Finally, suspension or withdrawal of the certificate or confiscation of the radioactive substances or devices do not give rise to compensation. (NEA) [fr

Biotreatment of industrial and hazardous waste

International Nuclear Information System (INIS)

Levin, M.A.; Gealt, M.A.

1993-01-01

This book attempts to approach the topic of biodegradation of hazardous wastes in a holistic fashion. The issues of science, engineering and regulation are all addressed. As much as possible, both theoretical and practical considerations have been dealt with. Selection of bacteria for the specific purpose of degrading compounds is discussed at the bench-scale to the field level. Engineering theory as applied to growth on toxic substances is discussed. The legal issues are covered. There are also several examples of field studies indicating the current usage of biodegradation, both within reactors and in situ. The use of biodegradation is compared with other mechanisms of disposal, in terms of time limitations, degradation limitations and, perhaps most important, cost. Individual papers have been processed separately for inclusion in the appropriate data bases

Frequency of damage by external explosion hazards based on geographical information

International Nuclear Information System (INIS)

Becker, Guenter; Camarinopoulos, Alexis; Theodora, Karali; Camarinopoulos, Leonidas; Schubert, B.

2013-01-01

External explosions can significantly contribute to risk of damage for industrial plants. External explosions may origin from other plants in the neighbourhood, which store and operate with explosive substances, or from transport of such substances on road, rail, or water. If deflagration is involved, ignition will not necessarily occur at the place of the accident, but a cloud of a combustible gas-air mixture may develop, which will ignite at some distance depending on wind velocity. A probabilistic model has been developed to calculate frequencies of damage based on numerical integration or on Monte Carlo simulation. Geographical information systems provide map material for sites, roads, rail and rivers on a computer. Data has been collected and applied for a nuclear power plant in Germany as an example. The method, however, can be used for any type of plant subject to external explosion hazards. (orig.)

Frequency of damage by external explosion hazards based on geographical information

Energy Technology Data Exchange (ETDEWEB)

Becker, Guenter [Risa Sicherheitsanalysen GmbH, Berlin-Charlottenburg (Germany); Camarinopoulos, Alexis; Theodora, Karali [Environment Reliability and Risk Analysis (ERRA), Athens (Greece); Camarinopoulos, Leonidas [Piraeus Univ. (Greece); Schubert, B. [VENE, Hamburg (Germany)

2013-05-15

External explosions can significantly contribute to risk of damage for industrial plants. External explosions may origin from other plants in the neighbourhood, which store and operate with explosive substances, or from transport of such substances on road, rail, or water. If deflagration is involved, ignition will not necessarily occur at the place of the accident, but a cloud of a combustible gas-air mixture may develop, which will ignite at some distance depending on wind velocity. A probabilistic model has been developed to calculate frequencies of damage based on numerical integration or on Monte Carlo simulation. Geographical information systems provide map material for sites, roads, rail and rivers on a computer. Data has been collected and applied for a nuclear power plant in Germany as an example. The method, however, can be used for any type of plant subject to external explosion hazards. (orig.)

Substance use - prescription drugs

Science.gov (United States)

Substance use disorder - prescription drugs; Substance abuse - prescription drugs; Drug abuse - prescription drugs; Drug use - prescription drugs; Narcotics - substance use; Opioid - substance use; Sedative - substance ...

Schedules of Controlled Substances: Temporary Placement of 4-Fluoroisobutyryl Fentanyl into Schedule I. Temporary scheduling order.

Science.gov (United States)

2017-05-03

The Administrator of the Drug Enforcement Administration is issuing this temporary scheduling order to schedule the synthetic opioid, N-(4-fluorophenyl)-N-(1-phenethylpiperidin-4-yl)isobutyramide (4-fluoroisobutyryl fentanyl or para-fluoroisobutyryl fentanyl), and its isomers, esters, ethers, salts and salts of isomers, esters, and ethers, into schedule I pursuant to the temporary scheduling provisions of the Controlled Substances Act. This action is based on a finding by the Administrator that the placement of 4-fluoroisobutyryl fentanyl into schedule I of the Controlled Substances Act is necessary to avoid an imminent hazard to the public safety. As a result of this order, the regulatory controls and administrative, civil, and criminal sanctions applicable to schedule I controlled substances will be imposed on persons who handle (manufacture, distribute, reverse distribute, import, export, engage in research, conduct instructional activities or chemical analysis, or possess), or propose to handle, 4-fluoroisobutyryl fentanyl.

Historical analysis of US pipeline accidents triggered by natural hazards

Science.gov (United States)

Girgin, Serkan; Krausmann, Elisabeth

2015-04-01

Natural hazards, such as earthquakes, floods, landslides, or lightning, can initiate accidents in oil and gas pipelines with potentially major consequences on the population or the environment due to toxic releases, fires and explosions. Accidents of this type are also referred to as Natech events. Many major accidents highlight the risk associated with natural-hazard impact on pipelines transporting dangerous substances. For instance, in the USA in 1994, flooding of the San Jacinto River caused the rupture of 8 and the undermining of 29 pipelines by the floodwaters. About 5.5 million litres of petroleum and related products were spilled into the river and ignited. As a results, 547 people were injured and significant environmental damage occurred. Post-incident analysis is a valuable tool for better understanding the causes, dynamics and impacts of pipeline Natech accidents in support of future accident prevention and mitigation. Therefore, data on onshore hazardous-liquid pipeline accidents collected by the US Pipeline and Hazardous Materials Safety Administration (PHMSA) was analysed. For this purpose, a database-driven incident data analysis system was developed to aid the rapid review and categorization of PHMSA incident reports. Using an automated data-mining process followed by a peer review of the incident records and supported by natural hazard databases and external information sources, the pipeline Natechs were identified. As a by-product of the data-collection process, the database now includes over 800,000 incidents from all causes in industrial and transportation activities, which are automatically classified in the same way as the PHMSA record. This presentation describes the data collection and reviewing steps conducted during the study, provides information on the developed database and data analysis tools, and reports the findings of a statistical analysis of the identified hazardous liquid pipeline incidents in terms of accident dynamics and

Bibliography of work on the photocatalytic removal of hazardous compounds from water and air

Energy Technology Data Exchange (ETDEWEB)

Blake, D.M.

1994-05-01

This is a bibliography of information in the open literature on work that has been done to date on the photocatalytic oxidation of compounds, principally organic compounds. The goal of the listing is removing hazardous oompounds from water or air. It contains lists of substances and literature citations. The bibliography includes information obtained through the middle of 1993 and some selected references for the balance of that year.

The Temporal Association between Substance Use and Intimate Partner Violence among Women Arrested for Domestic Violence

Science.gov (United States)

Stuart, Gregory L.; Moore, Todd M.; Elkins, Sara R.; O’Farrell, Timothy J.; Temple, Jeff R.; Ramsey, Susan; Shorey, Ryan C.

2013-01-01

Objective There is a paucity of research on the temporal association between substance use and intimate partner violence (IPV) perpetration and victimization, especially among women arrested for domestic violence. The current study examined whether the probability of IPV perpetration and victimization increases following alcohol or drug use relative to days of no use among women arrested for domestic violence. Method Women arrested for domestic violence and court referred to batterer intervention programs who met criteria for hazardous drinking participated in the current study (N=105). Women who reported drinking four or more drinks on one occasion at least once per month for the past six months were considered hazardous drinkers. Violence and substance use were assessed with the Timeline Followback Interviews for substance use and IPV. Results Women were more likely to perpetrate physical violence on a drinking day (OR=10.58; 95% CI=5.38–20.79) and on a heavy drinking day (OR=12.81; 95% CI=8.10–33.57), relative to a non-drinking day. Women were more likely to be victimized by physical violence on a drinking day (OR=5.22; 95% CI=2.79–9.77) and on a heavy drinking day (OR=6.16; 95% CI=3.25–11.68), relative to a non-drinking day. They were more likely to be victims of sexual coercion (OR=6.06; 95% CI=1.19–30.80) on a cocaine use day relative to a non-use day. Conclusions Alcohol use was temporally associated with physical violence perpetration and victimization, and cocaine use was temporally associated with sexual coercion victimization, suggesting that substance use should be targeted in batterer intervention programs for women. PMID:23647284

Determination and calculation of hazardous incident scenarios in accordance with the 3rd hazardous incident administrative instruction. Vol. 1; Ermittlung und Berechnung von Stoerfallablaufszenarien nach Massgabe der 3. Stoerfallverwaltungsvorschrift. Bd. 1: Methodischer Teil zum Erarbeiten von Stoerfallablaufszenarien

Energy Technology Data Exchange (ETDEWEB)

Kaiser, W.; Rogazewski, P.; Schindler, M. [TUeV Anlagentechnik GmbH, Berlin-Schoeneberg (Germany). Unternehmensgruppe TUeV Rheinland/Berlin-Brandenburg; Acikalin, A.; Albrecht, M.; Lambert, M.; Steinbach, J. [Technische Univ. Berlin (Germany)

2000-07-01

At present there are used various procedures, calculation methods, models and model equations for hazardous incident scenarios. The procedure on principle is varying often. This guideline explains in one main part and six appendixes the methodical procedure to select specifications and assumptions on hazardous incident scenarios and their processing. Hazardous incident scenarios lead to information on emergency preparedness planning. Both general viewpoints and possibilities are shown, how to find necessary basic assumptions on a hazardous incident scenario from information on hazardous substances, on comparable hazardous incidents and on conditions of the site and the plant. Appendixes deal with precise instructions distinguished between substance release, explosion and fire (App. 1: Assessment of source terms, App. 2: Assessment of dispersion, App. 3: Assessment of effects). Appendix 4 gives explanations to appendixes 1, 2 and 3. Appendix 5 contains a collection of 15 examples of hazardous incident scenarios, which illustrate and comment the methodical procedure. Appendix 6 describes and comments software available on German market which assists the calculating of hazardous incidents. Volume 2 determines procedures with regard to methods of calculation, current models and model equations from scientists' point of view. (orig.) [German] Derzeit wird eine Vielzahl von Vorgehensweisen, Berechnungsmethoden, Modellen und Modellgleichungen fuer Stoerfallablaufszenarien verwendet. Das prinzipielle Vorgehen ist haeufig unterschiedlich. Dieser Leitfaden enthaelt in einem Hauptteil und sechs Anhaengen das methodische Vorgehen zur Auswahl von Angaben und Annahmen fuer Stoerfallablaufszenarien sowie deren Bearbeitung. Stoerfallablaufszenarien fuehren zu Angaben fuer die Gefahrenabwehrplanung. Fuer das Ableiten von Stoerfallablaufszenarien sind sowohl allgemeine Gesichtspunkte als auch Moeglichkeiten dargelegt, wie man aus Angaben zu Gefahrstoffen, zu vergleichbaren

Relationship between alcohol consumption, whether linked to other substance use or not, and antiretroviral treatment adherence in HIV+ patients.

Science.gov (United States)

González-Álvarez, Sara; Madoz-Gúrpide, Agustín; Parro-Torres, Carlos; Hernández-Huerta, Daniel; Ochoa Mangado, Enriqueta

2017-07-14

Hazardous alcohol consumption is a common diagnosis among people living with HIV infection. The relationship between alcohol consumption and poor adherence to antiretroviral therapy has been highlighted in different studies, yet few of them performed a parallel analysis of other substance use. In Spain, alcohol consumption is frequently associated with other substance use, mainly cannabis and cocaine. The aim of this study is to assess the influence of hazardous alcohol consumption both combined with other substances (cocaine, heroin, methadone and/or cannabis) or alone on antiretroviral therapy adherence in our social environment. We performed an observational case-control study including 119 HIV+ individuals. We recruited 40 non-adherent patients, defined by less than 90% compliance according to hospital pharmacy refill data, and corroborated by the Simplified Medication Adherence Questionnaire (SMAQ) and referring professional's opinion. Control cases (n=79) were defined as those patients with similar characteristics but considered adherent according to the same parameters. Data collection took place between May 2013 and September 2015. Statistical analysis was performed using a binary logistic regression model. Our results indicate that alcohol consumption decreases adherence to antiretroviral therapy. The use of methadone represents a statistically significant increased risk of poor adherence. No significant differences were found between adherent and non-adherent groups regarding cocaine, heroin or cannabis use in this study. In summary, the detection of substance use and especially alcohol consumption in HIV+ patients can improve the effectiveness of antiretroviral therapy by identifying and treating at-risk individuals for a poor therapeutic adherence.

Substance misuse and substance use disorders in sex offenders: a review

NARCIS (Netherlands)

Kraanen, F.L.; Emmelkamp, P.M.G.

2011-01-01

Substance abuse has often been associated with committing sex offenses. In this article, the following will be reviewed: 1) studies that assessed substance abuse in sex offenders; 2) differences in substance abuse among different types of sex offenders; 3) differences in substance abuse between sex

Schedules of controlled substances: temporary placement of three synthetic cannabinoids into Schedule I. Final order.

Science.gov (United States)

2013-05-16

The Deputy Administrator of the Drug Enforcement Administration (DEA) is issuing this final order to temporarily schedule three synthetic cannabinoids under the Controlled Substances Act (CSA) pursuant to the temporary scheduling provisions of 21 U.S.C. 811(h). The substances are (1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone (UR-144), [1-(5-fluoro-pentyl)-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)methanone (5-fluoro-UR-144, XLR11) and N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide (APINACA, AKB48). This action is based on a finding by the Deputy Administrator that the placement of these synthetic cannabinoids and their salts, isomers and salts of isomers into Schedule I of the CSA is necessary to avoid an imminent hazard to the public safety. As a result of this order, the full effect of the CSA and the Controlled Substances Import and Export Act (CSIEA) and their implementing regulations including criminal, civil and administrative penalties, sanctions and regulatory controls of Schedule I substances will be imposed on the manufacture, distribution, possession, importation, and exportation of these synthetic cannabinoids.

[Synthetic cannabinoids: spread, addiction biology & current perspective of personal health hazard].

Science.gov (United States)

Bonnet, U; Mahler, H

2015-04-01

Among the new psychoactive substances (NPS), most frequently synthetic cannabinoids (SCBs) have been found in Europe. These are sold as active compounds in e. g. so-called "herbal blends". When inhaled or ingested, besides intoxication symptoms, as they occur with heavy cannabis use (e. g., tachycardia, myocardial infarction, confusion, hallucinations, panic attacks, and paranoia), harmful effects (severe agitation, coma, catatonic stupor, hypertension, cardiac arrhythmia, dyspnoea, seizures, myoclonus, rhabdomyolysis, hyperthermia, diaphoresis, acute kidney injury, vomiting, headache, and hypokalemia) arise, which are mostly unusual about cannabis use. In addition, the first cases of addiction and death related to SCBs have been reported. Taking into account the newest literature and using an algorithm with two main criteria (addiction potential, toxicity), the authors made a first attempt to rank the personal health hazard of SCBs in comparison to that of other psychoactive drugs. Accordingly, the relative health hazard of SCBs is found to be somewhat higher than that of cannabis and lower than that of synthetic cathinones ("bath salts"). However, the toxicity of SCBs, is significantly greater than the toxicity of cannabis, thus being similar to that of synthetic cathinones and benzodiazepines. The addiction potential appears to be lower than that of synthetic cathinones, benzodiazepines, or cannabis. Due to the fluctuation of substances and the availability in internet resources, legislation is facing a serious "hare-hedgehog" problem to control the manufacture, trade and possession of SCBs. © Georg Thieme Verlag KG Stuttgart · New York.

Transportation of Hazardous Materials Emergency Preparedness Hazards Assessment

Energy Technology Data Exchange (ETDEWEB)

Blanchard, A.

2000-02-28

This report documents the Emergency Preparedness Hazards Assessment (EPHA) for the Transportation of Hazardous Materials (THM) at the Department of Energy (DOE) Savannah River Site (SRS). This hazards assessment is intended to identify and analyze those transportation hazards significant enough to warrant consideration in the SRS Emergency Management Program.

Transportation of Hazardous Materials Emergency Preparedness Hazards Assessment

International Nuclear Information System (INIS)

Blanchard, A.

2000-01-01

This report documents the Emergency Preparedness Hazards Assessment (EPHA) for the Transportation of Hazardous Materials (THM) at the Department of Energy (DOE) Savannah River Site (SRS). This hazards assessment is intended to identify and analyze those transportation hazards significant enough to warrant consideration in the SRS Emergency Management Program

Transportation of hazardous materials emergency preparedness hazards assessment

International Nuclear Information System (INIS)

Blanchard, A.

2000-01-01

This report documents the Emergency Preparedness Hazards Assessment (EPHA) for the Transportation of Hazardous Materials (THM) at the Department of Energy (DOE) Savannah River Site (SRS). This hazards assessment is intended to identify and analyze those transportation hazards significant enough to warrant consideration in the SRS Emergency Management Program

Autoradiographic localization of substance P receptors using 125I substance P

International Nuclear Information System (INIS)

Shults, C.W.; Quirion, R.; Jensen, R.T.; Moody, T.W.; O'Donohue, T.L.; Chase, T.N.

1982-01-01

This paper describes a method for localization of substance P receptors in the rat central nervous system using 125 I labeled substance P in an autoradiographic procedure. Particularly high densities of substance P receptors were observed in the olfactory bulb, dentate gyrus, amygdala, superior colliculus, and locus coeruleus. Surprisingly low densities of substance P receptors were found in the substantia nigra pars reticulata, a region which contains high concentrations of substance P

Impact of parental history of substance use disorders on the clinical course of anxiety disorders

Directory of Open Access Journals (Sweden)

Moskowitz Amanda T

2007-04-01

Full Text Available Abstract Background Among the psychological difficulties seen in children of parents with substance use problems, the anxiety disorders are among the most chronic conditions. Although children of alcoholic parents often struggle with the effects of parental substance use problems long into adulthood, empirical investigations of the influence of parental substance use disorders on the course of anxiety disorders in adult offspring are rare. The purpose of this study was to examine prospectively the relationship between parental substance use disorders and the course of anxiety disorders in adulthood over the course of 12 years. Methods Data on 618 subjects were derived from the Harvard/Brown Anxiety Research Project (HARP, a longitudinal naturalistic investigation of the clinical course of multiple anxiety disorders. Kaplan-Meier survival estimates were used to calculate probabilities of time to anxiety disorder remission and relapse. Proportional hazards regressions were conducted to determine whether the likelihood of remission and relapse for specific anxiety disorders was lower for those who had a history of parental substance use disorders than for individuals without this parental history. Results Adults with a history of parental substance use disorders were significantly more likely to be divorced and to have a high school level of education. History of parental substance use disorder was a significant predictor of relapse of social phobia and panic disorders. Conclusion These findings provide compelling evidence that adult children of parents with substance use disorders are more likely to have relapses of social phobia and panic disorders. Clinicians who treat adults with anxiety disorders should assess parental substance use disorders and dependence histories. Such information may facilitate treatment planning with regards to their patients' level of vulnerability to perceive scrutiny by others in social situations, and ability to

Project management plan, Hazardous Materials Management and Emergency Response Training Center

International Nuclear Information System (INIS)

Borgeson, M.E.

1994-01-01

For the next 30 years, the main activities at the Hanford Site will involve the handling and cleanup of toxic substances. Thousands of workers involved in these new activities will need systematic training appropriate to their tasks and associated risks. This project is an important part of the Hanford Site mission and will enable the US Department of Energy (DOE) to meet high standards for safety. The Hazardous Materials Management and Emergency Response Training Center (HAMMER) project will construct a centralized regional training center dedicated to training hazardous materials workers and emergency responders in classrooms and with hands-on, realistic training aids representing actual field conditions. The HAMMER Training Center will provide a cost-effective, high-quality way to meet the Hanford Site training needs. The training center creates a partnership among DOE; government contractors; labor; local, state, and tribal governments; and selected institutions of higher education

Hazard function theory for nonstationary natural hazards

Science.gov (United States)

Read, L.; Vogel, R. M.

2015-12-01

Studies from the natural hazards literature indicate that many natural processes, including wind speeds, landslides, wildfires, precipitation, streamflow and earthquakes, show evidence of nonstationary behavior such as trends in magnitudes through time. Traditional probabilistic analysis of natural hazards based on partial duration series (PDS) generally assumes stationarity in the magnitudes and arrivals of events, i.e. that the probability of exceedance is constant through time. Given evidence of trends and the consequent expected growth in devastating impacts from natural hazards across the world, new methods are needed to characterize their probabilistic behavior. The field of hazard function analysis (HFA) is ideally suited to this problem because its primary goal is to describe changes in the exceedance probability of an event over time. HFA is widely used in medicine, manufacturing, actuarial statistics, reliability engineering, economics, and elsewhere. HFA provides a rich theory to relate the natural hazard event series (x) with its failure time series (t), enabling computation of corresponding average return periods and reliabilities associated with nonstationary event series. This work investigates the suitability of HFA to characterize nonstationary natural hazards whose PDS magnitudes are assumed to follow the widely applied Poisson-GP model. We derive a 2-parameter Generalized Pareto hazard model and demonstrate how metrics such as reliability and average return period are impacted by nonstationarity and discuss the implications for planning and design. Our theoretical analysis linking hazard event series x, with corresponding failure time series t, should have application to a wide class of natural hazards.

Hazard function theory for nonstationary natural hazards

Science.gov (United States)

Read, Laura K.; Vogel, Richard M.

2016-04-01

Impact from natural hazards is a shared global problem that causes tremendous loss of life and property, economic cost, and damage to the environment. Increasingly, many natural processes show evidence of nonstationary behavior including wind speeds, landslides, wildfires, precipitation, streamflow, sea levels, and earthquakes. Traditional probabilistic analysis of natural hazards based on peaks over threshold (POT) generally assumes stationarity in the magnitudes and arrivals of events, i.e., that the probability of exceedance of some critical event is constant through time. Given increasing evidence of trends in natural hazards, new methods are needed to characterize their probabilistic behavior. The well-developed field of hazard function analysis (HFA) is ideally suited to this problem because its primary goal is to describe changes in the exceedance probability of an event over time. HFA is widely used in medicine, manufacturing, actuarial statistics, reliability engineering, economics, and elsewhere. HFA provides a rich theory to relate the natural hazard event series (X) with its failure time series (T), enabling computation of corresponding average return periods, risk, and reliabilities associated with nonstationary event series. This work investigates the suitability of HFA to characterize nonstationary natural hazards whose POT magnitudes are assumed to follow the widely applied generalized Pareto model. We derive the hazard function for this case and demonstrate how metrics such as reliability and average return period are impacted by nonstationarity and discuss the implications for planning and design. Our theoretical analysis linking hazard random variable X with corresponding failure time series T should have application to a wide class of natural hazards with opportunities for future extensions.

Reduction in soil loss from erosion-susceptible soils amended with humic substances from oxidized coal

International Nuclear Information System (INIS)

Piccolo, A.; Pietramellara, G.; Mbagwu, J.S.C.

1997-01-01

Soils that pose high risk of erosion require amendment with either natural or synthetic soil conditioners to reduce soil loss hazards. The objective of this study was to evaluate the potential of using coal-derived humic substances (as soil conditioners) to reduce runoff erosion on erosion-susceptible soils. Surface samples of severely degraded soils from Principina in Tuscany and Bovolone in Venice in Italy were used to assess the effects of five rates (0, 0.05, 0.01, 0.50 and 1.00 g/kg) of humic acids (HA) on soil loss and other hydrological parameters. The results showed that amending erosion-susceptible soils with low rates of coal-derived humic substances is a potentially effective soil management practice for reducing erosion rates

Air conditioning systems as non-infectious health hazards inducing acute respiratory symptoms.

Science.gov (United States)

Gerber, Alexander; Fischer, Axel; Willig, Karl-Heinz; Groneberg, David A

2006-04-01

Chronic and acute exposure to toxic aerosols belongs to frequent causes of airway diseases. However, asthma attacks due to long-distance inhalative exposure to organic solvents, transmitted via an air condition system, have not been reported so far. The present case illustrates the possibility of air conditioning systems as non-infectious health hazards in occupational medicine. So far, only infectious diseases such as legionella pneumophila pneumonia have commonly been associated to air-conditioning exposures but physicians should be alert to the potential of transmission of toxic volatile substances via air conditioning systems. In view of the events of the 11th of September 2001 with a growing danger of large building terrorism which may even use air conditioning systems to transmit toxins, facility management security staff should be alerted to possible non-infectious toxic health hazards arising from air-conditioning systems.

Substance misuse and substance use disorders in sex offenders: a review.

Science.gov (United States)

Kraanen, Fleur L; Emmelkamp, Paul M G

2011-04-01

Substance abuse has often been associated with committing sex offenses. In this article, the following will be reviewed: 1) studies that assessed substance abuse in sex offenders; 2) differences in substance abuse among different types of sex offenders; 3) differences in substance abuse between sex offenders and nonsexual offenders and substance abuse in the normal population; 4) sex offenders' intoxication at the time of the offense; and 5) differences in intoxication at the time of the offense among different types of sex offenders. Studies will be discussed according to the method they used to assess substance abuse, i.e., file research, screening instruments or semi-structured interviews. This review shows that about half of the sex offenders has a history of substance abuse, a quarter to half of the sex offenders has a history of alcohol misuse and that about one fifth to a quarter of the sex offenders has a history of drug misuse. Furthermore, about a quarter to half of the sex offenders appeared to be intoxicated at the time of the offense. The review results in recommendations for future research. Because of the high prevalence of substance abuse in sex offenders it is advisable to routinely screen for substance abuse and, if necessary, to treat substance abuse. Copyright © 2010 Elsevier Ltd. All rights reserved.

Environmental hazard analysis - contamination of nutrients, mercury and cesium-137 in natural waters

International Nuclear Information System (INIS)

Hakanson, L.

1990-01-01

Results from some ongoing Swedish research projects on different types of contamination of limnic as well as marine areas are summarized. A brief theoretical outline on the central concepts of the 'meso-scale-type' of environmental hazard analysis, utilizing examples on eutrophication of coastal waters is given. The concepts are further substantiated in two subsequent parts dealing with radioactive cesium and mercury. The idea is to illustrate that the basic concepts for ('real' world/'meso scale') environmental hazard analysis can be used for different substances and different aquatic environments. It is important to give clear, quantifiable definitions of the effect, dose and environmental sensitivity parameters, which should be valid for a defined area and for a defined span of time. All other parameters should be compatible and have the same area and time resolution. (author)

Does dissatisfaction with psychosocial work climate predict depressive, anxiety and substance abuse disorders? A prospective study of Danish public service employees

DEFF Research Database (Denmark)

Jensen, H K; Wieclaw, Joanna; Munch-Hansen, Torsten

2010-01-01

were divided into three levels, according to the 25-75 percentiles. Data on hospitalisations and outpatient treatments for depressive, anxiety and substance abuse disorders was obtained from the Danish Central Psychiatric Research Register. Hazard ratios and 95 % confidence intervals were computed.......71, 95 % CI 1.04-2.82). The lower the satisfaction level, the higher was the risk of mental health disorders. Moreover, substance abuse disorders were more frequent among men dissatisfied with work climate, HRadj of 3.53, 95 % CI 1.55-8.03. CONCLUSION: Working in a dissatisfying psychosocial environment...

Hazards assessment for the Hazardous Waste Storage Facility

International Nuclear Information System (INIS)

Knudsen, J.K.; Calley, M.B.

1994-04-01

This report documents the hazards assessment for the Hazardous Waste Storage Facility (HWSF) located at the Idaho National Engineering Laboratory. The hazards assessment was performed to ensure that this facility complies with DOE and company requirements pertaining to emergency planning and preparedness for operational emergencies. The hazards assessment identifies and analyzes hazards that are significant enough to warrant consideration in a facility's operational emergency management program. The area surrounding HWSF, the buildings and structures at HWSF, and the processes used at HWSF are described in this report. All nonradiological hazardous materials at the HWSF were identified (radiological hazardous materials are not stored at HWSF) and screened against threshold quantities according to DOE Order 5500.3A guidance. Two of the identified hazardous materials exceeded their specified threshold quantity. This report discusses the potential release scenarios and consequences associated with an accidental release for each of the two identified hazardous materials, lead and mercury. Emergency considerations, such as emergency planning zones, emergency classes, protective actions, and emergency action levels, are also discussed based on the analysis of potential consequences. Evaluation of the potential consequences indicated that the highest emergency class for operational emergencies at the HWSF would be a Site Area Emergency

Study on anaerobic treatment of hazardous steel-mill waste rolling oil (SmWRO) for multi-benefit disposal route.

Science.gov (United States)

Ma, Huanhuan; Li, Zifu; Yin, Fubin; Kao, William; Yin, Yi; Bai, Xiaofeng

2014-01-01

Steel-mill waste rolling oil (SmWRO) is considered as hazardous substance with high treatment and disposal fees. Anaerobic process could not only transform the hazardous substance into activated sludge, but also generate valuable biogas. This study aimed at studying the biochemical methane potential of SmWRO under inoculum to substrate VS ratios (ISRs) of 0.25, 0.5, 1, 1.5, 2 and 3 using septic tank sludge as inoculum in mesophilic and thermophilic conditions, with blank tests for control. Specific biogas yield (mL/g VS(added)), net biogas yield (mL/g VS(removed)) and VS removal were analyzed. The ANOVA results indicated great influence of ISR and temperature on studied parameters. ISR of 1.5 at 55°C and ISR of 1.5 and 2 at 35°C were suggested with the highest specific biogas yield (262-265 and 303mL/g VS(added)). Kinetic analysis showed that Gompertz model fit the experimental data best with the least RMSE and largest R(2). Copyright © 2013 Elsevier Ltd. All rights reserved.

Scientific Issues Relevant to Setting Regulatory Criteria to Identify Endocrine-Disrupting Substances in the European Union.

Science.gov (United States)

Slama, Rémy; Bourguignon, Jean-Pierre; Demeneix, Barbara; Ivell, Richard; Panzica, Giancarlo; Kortenkamp, Andreas; Zoeller, R Thomas

2016-10-01

Endocrine disruptors (EDs) are defined by the World Health Organization (WHO) as exogenous compounds or mixtures that alter function(s) of the endocrine system and consequently cause adverse effects in an intact organism, or its progeny, or (sub)populations. European regulations on pesticides, biocides, cosmetics, and industrial chemicals require the European Commission to establish scientific criteria to define EDs. We address the scientific relevance of four options for the identification of EDs proposed by the European Commission. Option 1, which does not define EDs and leads to using interim criteria unrelated to the WHO definition of EDs, is not relevant. Options 2 and 3 rely on the WHO definition of EDs, which is widely accepted by the scientific community, with option 3 introducing additional categories based on the strength of evidence (suspected EDs and endocrine-active substances). Option 4 adds potency to the WHO definition, as a decision criterion. We argue that potency is dependent on the adverse effect considered and is scientifically ambiguous, and note that potency is not used as a criterion to define other particularly hazardous substances such as carcinogens and reproductive toxicants. The use of potency requires a context that goes beyond hazard identification and corresponds to risk characterization, in which potency (or, more relevantly, the dose-response function) is combined with exposure levels. There is scientific agreement regarding the adequacy of the WHO definition of EDs. The potency concept is not relevant to the identification of particularly serious hazards such as EDs. As is common practice for carcinogens, mutagens, and reproductive toxicants, a multi-level classification of ED based on the WHO definition, and not considering potency, would be relevant (corresponding to option 3 proposed by the European Commission). Slama R, Bourguignon JP, Demeneix B, Ivell R, Panzica G, Kortenkamp A, Zoeller RT. 2016. Scientific issues relevant

Parity for mental health and substance abuse care under managed care.

Science.gov (United States)

Frank, Richard G.; McGuire, Thomas G.

1998-12-01

BACKGROUND: Parity in insurance coverage for mental health and substance abuse has been a key goal of mental health and substance abuse care advocates in the United States during most of the past 20 years. The push for parity began during the era of indemnity insurance and fee for service payment when benefit design was the main rationing device in health care. The central economic argument for enacting legislation aimed at regulating the insurance benefit was to address market failure stemming from adverse selection. The case against parity was based on inefficiency related to moral hazard. Empirical analyses provided evidence that ambulatory mental health services were considerably more responsive to the terms of insurance than were ambulatory medical services. AIMS: Our goal in this research is to reexamine the economics of parity in the light of recent changes in the delivery of health care in the United States. Specifically managed care has fundamentally altered the way in which health services are rationed. Benefit design is now only one mechanism among many that are used to allocate health care resources and control costs. We examine the implication of these changes for policies aimed at achieving parity in insurance coverage. METHOD: We develop a theoretical approach to characterizing rationing under managed care. We then analyze the traditional efficiency concerns in insurance, adverse selection and moral hazard in the context of policy aimed at regulating health and mental health benefits under private insurance. RESULTS: We show that since managed care controls costs and utilization in new ways parity in benefit design no longer implies equal access to and quality of mental health and substance abuse care. Because costs are controlled by management under managed care and not primarily by out of pocket prices paid by consumers, demand response recedes as an efficiency argument against parity. At the same time parity in benefit design may accomplish less

Battery collection in municipal waste management in Japan: Challenges for hazardous substance control and safety

International Nuclear Information System (INIS)

Terazono, Atsushi; Oguchi, Masahiro; Iino, Shigenori; Mogi, Satoshi

2015-01-01

Highlights: • Consumers need to pay attention to the specific collection rules for each type of battery in each municipality in Japan. • 6–10% of zinc carbon and alkaline batteries discarded in Japan currently could be regarded as containing mercury. • Despite announcements by producers and municipalities, only 2.0% of discarded cylindrical dry batteries were insulated. • Batteries made up an average of 4.6% of the total collected small WEEE under the small WEEE recycling scheme in Japan. • Exchangeable batteries were used in almost all of mobile phones, but the removal rate was as low as 22% for mobile phones. - Abstract: To clarify current collection rules of waste batteries in municipal waste management in Japan and to examine future challenges for hazardous substance control and safety, we reviewed collection rules of waste batteries in the Tokyo Metropolitan Area. We also conducted a field survey of waste batteries collected at various battery and small waste electric and electronic equipment (WEEE) collection sites in Tokyo. The different types of batteries are not collected in a uniform way in the Tokyo area, so consumers need to pay attention to the specific collection rules for each type of battery in each municipality. In areas where small WEEE recycling schemes are being operated after the enforcement of the Act on Promotion of Recycling of Small Waste Electrical and Electronic Equipment in Japan in 2013, consumers may be confused about the need for separating batteries from small WEEE (especially mobile phones). Our field survey of collected waste batteries indicated that 6–10% of zinc carbon and alkaline batteries discarded in Japan currently could be regarded as containing mercury. More than 26% of zinc carbon dry batteries currently being discarded may have a lead content above the labelling threshold of the EU Batteries Directive (2006/66/EC). In terms of safety, despite announcements by producers and municipalities about using

Battery collection in municipal waste management in Japan: Challenges for hazardous substance control and safety

Energy Technology Data Exchange (ETDEWEB)

Terazono, Atsushi, E-mail: terazono@nies.go.jp [National Institute for Environmental Studies, 16-2 Onogawa, Tsukuba, Ibaraki 305-8506 (Japan); Oguchi, Masahiro [National Institute for Environmental Studies, 16-2 Onogawa, Tsukuba, Ibaraki 305-8506 (Japan); Iino, Shigenori [Tokyo Metropolitan Research Institute for Environmental Protection, 1-7-5 Shinsuna, Koto-ku, Tokyo 136-0075 (Japan); Mogi, Satoshi [Bureau of Environment, Tokyo Metropolitan Government, 2-8-1 Nishi-shinjuku, Shinjuku-ku, Tokyo 163-8001 (Japan)

2015-05-15

Highlights: • Consumers need to pay attention to the specific collection rules for each type of battery in each municipality in Japan. • 6–10% of zinc carbon and alkaline batteries discarded in Japan currently could be regarded as containing mercury. • Despite announcements by producers and municipalities, only 2.0% of discarded cylindrical dry batteries were insulated. • Batteries made up an average of 4.6% of the total collected small WEEE under the small WEEE recycling scheme in Japan. • Exchangeable batteries were used in almost all of mobile phones, but the removal rate was as low as 22% for mobile phones. - Abstract: To clarify current collection rules of waste batteries in municipal waste management in Japan and to examine future challenges for hazardous substance control and safety, we reviewed collection rules of waste batteries in the Tokyo Metropolitan Area. We also conducted a field survey of waste batteries collected at various battery and small waste electric and electronic equipment (WEEE) collection sites in Tokyo. The different types of batteries are not collected in a uniform way in the Tokyo area, so consumers need to pay attention to the specific collection rules for each type of battery in each municipality. In areas where small WEEE recycling schemes are being operated after the enforcement of the Act on Promotion of Recycling of Small Waste Electrical and Electronic Equipment in Japan in 2013, consumers may be confused about the need for separating batteries from small WEEE (especially mobile phones). Our field survey of collected waste batteries indicated that 6–10% of zinc carbon and alkaline batteries discarded in Japan currently could be regarded as containing mercury. More than 26% of zinc carbon dry batteries currently being discarded may have a lead content above the labelling threshold of the EU Batteries Directive (2006/66/EC). In terms of safety, despite announcements by producers and municipalities about using

Assessment of the Radioprotection Efficacy of Antioxidant Substances in Foods in regard to Clonogenic Cell Survival

Energy Technology Data Exchange (ETDEWEB)

Park, Hyosung; Lee, Minho; Kim, Eunhee [Seoul National Univ., Seoul (Korea, Republic of)

2014-05-15

Radiation is perceived as a hazard in spite of its diverse uses. The public are more sensitive than ever to the activities from the nuclear power plant industry since Fukushima accident and the consequential environment contamination. The never-dissolved fear from the public of the nuclear energy costs the nuclear industry too much for safety measures not to mention brings the public uneasy life. Beta carotene, oltipraz and luteolin, which are easily taken from various foods, are substances that may protect cells from damage caused by unstable molecules known as free radicals. The purpose of this study is to inform people of accessible radiation protection measures in everyday lives. Three antioxidant substances were investigated regarding their radioprotection effects counted in terms of clonogenic cell surviving fraction in vitro. The radioprotection efficacy was observed with those substances at concentrations below certain levels. At concentrations beyond those levels, the efficacy was canceled out by their inherent cytotoxicity.

Epidemiology of Substance Use among Forced Migrants: A Global Systematic Review.

Directory of Open Access Journals (Sweden)

Danielle Horyniak

Full Text Available Forced migration is occurring at unprecedented levels. Forced migrants may be at risk for substance use for reasons including coping with traumatic experiences, co-morbid mental health disorders, acculturation challenges and social and economic inequality. This paper aimed to systematically review the literature examining substance use among forced migrants, and identify priority areas for intervention and future research.Seven medical, allied health and social science databases were searched from inception to September 2015 in accordance with PRISMA guidelines to identify original peer-reviewed articles describing any findings relating to alcohol and/or illicit drug use among refugees, internally displaced people (IDPs, asylum seekers, people displaced by disasters and deportees. A descriptive synthesis of evidence from quantitative studies was conducted, focusing primarily on studies which used validated measures of substance use. Synthesis of evidence from qualitative studies focused on identifying prominent themes relating to the contexts and consequences of substance use. Critical Appraisal Skills Programme (CASP checklists were used to assess methodological quality of included studies.Forty-four quantitative (82% cross-sectional, 16 qualitative and three mixed-methods studies were included. Ten studies were rated as high methodological quality (16%, 39 as moderate quality (62% and 14 as low quality (22%. The majority of research was conducted among refugees, IDPs and asylum seekers (n = 55, 87%, predominantly in high-income settings. The highest-quality prevalence estimates of hazardous/harmful alcohol use ranged from 17%-36% in camp settings and 4%-7% in community settings. Few studies collected validated measures of illicit drug use. Seven studies compared substance use among forced migrants to other migrant or native-born samples. Among eight studies which conducted multivariable analysis, male sex, trauma exposure and symptoms of

A study of tobacco and substance abuse among mentally ill outpatients in a tertiary care general hospital

Directory of Open Access Journals (Sweden)

Anju Gupta

2016-01-01

Full Text Available Background: The comorbidity of substance abuse and mental disorder is known to exist and may cause many diagnostic, prognostic, and management difficulties. Indian data are sparse in this area. Objectives: The aim of the study was to identify the prevalence and pattern of substance abuse in psychiatric outpatients and to examine the relation between demographic variables and drug abuse pattern. Materials and Methods: Medical records of the patients attending psychiatry outpatient clinic at a tertiary care general hospital over a 3-month period were reviewed. Information was obtained from medical chart and Drug Abuse Monitoring Scale pro forma about substance abuse. Psychiatric diagnosis made by a qualified psychiatrist according to the Diagnostic and Statistical Manual of Mental Disorders Fourth Edition diagnostic criteria, as recorded in the case record form, was used. Observation: The results revealed that 50.8% (half of all psychiatry outpatients were using one or more substances including tobacco in the last month prior to registration (1 month prevalence and 28.35% were using substances at any time in their life prior to the last month (lifetime prevalence. Male patients had 6 to 8 times higher substance abuse than female patients. Tobacco and alcohol were found to be the most common substances of abuse, followed by cannabis. Part-time and full-time employed male patients consumed more alcohol and tobacco than unemployed patients. Conclusions: Substance abuse was common among mentally ill outpatients and could be the cause of various health hazards and hence requires due attention.

An exploratory screening of organic substances in combustion residues; En orienterande screening av organiska aemnen i askor

Energy Technology Data Exchange (ETDEWEB)

Larsson, Lennart; Lind, Bo (Swedish Geotechnical Inst., Linkoeping (Sweden)); Bjurstroem, Henrik (AaF-Process, Stockholm (Sweden))

2008-09-15

Ash consists of the inorganic incombustible part of fuels, but it also always contains a small amount of organic matter, occurring as trace substances with concentrations in the order of mg/kg and lower. A few types of compounds are analysed comparatively frequently, e.g. PCDD/F (the so-called dioxins), but knowledge about the other organic substances is far from exhaustive. In this investigation, three ash samples have been subjected to a semi-quantitative GC/MS screening of semi-volatile substances. In this method of analysis the substances are extracted, separated in a gas chromatograph and identified as well as quantified using a mass spectrometer. Even if this type of analysis can be performed by researchers at universities, we chose to let commercial analytical laboratories do it in order to assess results from a nearly routine work. Residues from woody biofuels (recovered wood, virgin wood and bark) were chosen in order to complement the information that has previously been obtained on ash from municipal solid waste incineration. The GC/MS screening was carried out on both non-derivatised samples (non-polar compounds) and derivatised samples (polar compounds). The investigation aimed also at assessing the potential and the limitations of the screening method. In addition, the potentially hazardous properties of each identified substance were examined. Screening without and with derivatization is a cost-effective method to chart the content of semi-volatile organic substances. The results are relevant, but the method commercially available in Sweden is at present not mature enough for the use considered. It must be further developed before it can be included in e.g. regulatory texts. Limitations may be found in several steps of the method, principally: - Extraction and derivatisation, as the internal standard added is recovered only to a small extent for some ash samples, indicating that not everything has been found - Detection, i.e. both the sensitivity of

Hazard interactions and interaction networks (cascades) within multi-hazard methodologies

Science.gov (United States)

Gill, Joel C.; Malamud, Bruce D.

2016-08-01

This paper combines research and commentary to reinforce the importance of integrating hazard interactions and interaction networks (cascades) into multi-hazard methodologies. We present a synthesis of the differences between multi-layer single-hazard approaches and multi-hazard approaches that integrate such interactions. This synthesis suggests that ignoring interactions between important environmental and anthropogenic processes could distort management priorities, increase vulnerability to other spatially relevant hazards or underestimate disaster risk. In this paper we proceed to present an enhanced multi-hazard framework through the following steps: (i) description and definition of three groups (natural hazards, anthropogenic processes and technological hazards/disasters) as relevant components of a multi-hazard environment, (ii) outlining of three types of interaction relationship (triggering, increased probability, and catalysis/impedance), and (iii) assessment of the importance of networks of interactions (cascades) through case study examples (based on the literature, field observations and semi-structured interviews). We further propose two visualisation frameworks to represent these networks of interactions: hazard interaction matrices and hazard/process flow diagrams. Our approach reinforces the importance of integrating interactions between different aspects of the Earth system, together with human activity, into enhanced multi-hazard methodologies. Multi-hazard approaches support the holistic assessment of hazard potential and consequently disaster risk. We conclude by describing three ways by which understanding networks of interactions contributes to the theoretical and practical understanding of hazards, disaster risk reduction and Earth system management. Understanding interactions and interaction networks helps us to better (i) model the observed reality of disaster events, (ii) constrain potential changes in physical and social vulnerability

Comparative alternative materials assessment to screen toxicity hazards in the life cycle of CIGS thin film photovoltaics

International Nuclear Information System (INIS)

Eisenberg, Daniel A.; Yu, Mengjing; Lam, Carl W.; Ogunseitan, Oladele A.; Schoenung, Julie M.

2013-01-01

Highlights: • Comparative alternatives assessment of thin film manufacturing technologies. • Development of chemical alternatives assessment in a life cycle context. • Screening of manufacturing and solar cell hazardous substances simultaneously. -- Abstract: Copper–indium–gallium–selenium–sulfide (CIGS) thin film photovoltaics are increasingly penetrating the market supply for consumer solar panels. Although CIGS is attractive for producing less greenhouse gas emissions than fossil-fuel based energy sources, CIGS manufacturing processes and solar cell devices use hazardous materials that should be carefully considered in evaluating and comparing net environmental benefits of energy products. Through this research, we present a case study on the toxicity hazards associated with alternative materials selection for CIGS manufacturing. We applied two numeric models, The Green Screen for Safer Chemicals™ and the Toxic Potential Indicator. To improve the sensitivity of the model outputs, we developed a novel, life cycle thinking based hazard assessment method that facilitates the projection of hazards throughout material life cycles. Our results show that the least hazardous CIGS solar cell device and manufacturing protocol consist of a titanium substrate, molybdenum metal back electrode, CuInS 2 p-type absorber deposited by spray pyrolysis, ZnS buffer deposited by spray ion layer gas reduction, ZnO:Ga transparent conducting oxide (TCO) deposited by sputtering, and the encapsulant polydimethylsiloxane

RAPID-N: Assessing and mapping the risk of natural-hazard impact at industrial installations

Science.gov (United States)

Girgin, Serkan; Krausmann, Elisabeth

2015-04-01

Natural hazard-triggered technological accidents (so-called Natech accidents) at hazardous installations can have major consequences due to the potential for release of hazardous materials, fires and explosions. Effective Natech risk reduction requires the identification of areas where this risk is high. However, recent studies have shown that there are hardly any methodologies and tools that would allow authorities to identify these areas. To work towards closing this gap, the European Commission's Joint Research Centre has developed the rapid Natech risk assessment and mapping framework RAPID-N. The tool, which is implemented in an online web-based environment, is unique in that it contains all functionalities required for running a full Natech risk analysis simulation (natural hazards severity estimation, equipment damage probability and severity calculation, modeling of the consequences of loss of containment scenarios) and for visualizing its results. The output of RAPID-N are risk summary reports and interactive risk maps which can be used for decision making. Currently, the tool focuses on Natech risk due to earthquakes at industrial installations. However, it will be extended to also analyse and map Natech risk due to floods in the near future. RAPID-N is available at http://rapidn.jrc.ec.europa.eu. This presentation will discuss the results of case-study calculations performed for selected flammable and toxic substances to test the capabilities of RAPID-N both for single- and multi-site earthquake Natech risk assessment. For this purpose, an Istanbul earthquake scenario provided by the Turkish government was used. The results of the exercise show that RAPID-N is a valuable decision-support tool that assesses the Natech risk and maps the consequence end-point distances. These end-point distances are currently defined by 7 kPa overpressure for Vapour Cloud Explosions, 2nd degree burns for pool fire (which is equivalent to a heat radiation of 5 kW/m2 for 40s

The transportation of hazardous materials

International Nuclear Information System (INIS)

Hillman, J.C.

1981-04-01

The increasing use of dangerous chemicals and petroleum products by S.A. industry makes it necessary for some form of control to be introduced to regulate the transport of these materials before a major disaster occurs, such as has occurred overseas. This report examines all the aspects that could increase the likelihood of such a disaster occurring, including the preparedness of emergency services. It also recommends the improvements or changes required to minimize this possibility. It is apparent that the training and ability of vehicle drivers are key areas in this respect and they are discussed at length. Forthcoming regulations under the Hazardous Substances Act No. 15 of 1973 are examined and the effects of over-restrictive legislation considered. The report concludes that legislation promulgated gradually to reinforce voluntary industrial practices will ultimately restrict this type of transport to the safety-conscious and competent operator, therefore minimizing the risk as much as possible

Waste Issues Associated with the Safe Movement of Hazardous Chemicals

International Nuclear Information System (INIS)

Dare, J. H.; Cournoyer, M. E.

2002-01-01

Moving hazardous chemicals presents the risk of exposure for workers engaged in the activity and others that might be in the immediate area. Adverse affects are specific to the chemicals and can range from minor skin, eye, or mucous membrane irritation, to burns, respiratory distress, nervous system dysfunction, or even death. A case study is presented where in the interest of waste minimization; original shipping packaging was removed from a glass bottle of nitric acid, while moving corrosive liquid through a security protocol into a Radiological Control Area (RCA). During the transfer, the glass bottle broke. The resulting release of nitric acid possibly exposed 12 employees with one employee being admitted overnight at a hospital for observation. This is a clear example of administrative controls to reduce the generation of suspect radioactive waste being implemented at the expense of employee health. As a result of this event, material handling procedures that assure the safe movement of hazardous chemicals through a security protocol into a radiological control area were developed. Specifically, hazardous material must be transferred using original shipping containers and packaging. While this represents the potential to increase the generation of suspect radioactive waste in a radiological controlled area, arguments are presented that justify this change. Security protocols for accidental releases are also discussed. In summary, the 12th rule of ''Green Chemistry'' (Inherently Safer Chemistry for Accident Prevention) should be followed: the form of a substance used in a chemical process (Movement of Hazardous Chemicals) should be chosen to minimize the potential for chemical accidents, including releases

Waste Issues Associated with the Safe Movement of Hazardous Chemicals

Energy Technology Data Exchange (ETDEWEB)

Dare, J. H.; Cournoyer, M. E.

2002-02-26

Moving hazardous chemicals presents the risk of exposure for workers engaged in the activity and others that might be in the immediate area. Adverse affects are specific to the chemicals and can range from minor skin, eye, or mucous membrane irritation, to burns, respiratory distress, nervous system dysfunction, or even death. A case study is presented where in the interest of waste minimization; original shipping packaging was removed from a glass bottle of nitric acid, while moving corrosive liquid through a security protocol into a Radiological Control Area (RCA). During the transfer, the glass bottle broke. The resulting release of nitric acid possibly exposed 12 employees with one employee being admitted overnight at a hospital for observation. This is a clear example of administrative controls to reduce the generation of suspect radioactive waste being implemented at the expense of employee health. As a result of this event, material handling procedures that assure the safe movement of hazardous chemicals through a security protocol into a radiological control area were developed. Specifically, hazardous material must be transferred using original shipping containers and packaging. While this represents the potential to increase the generation of suspect radioactive waste in a radiological controlled area, arguments are presented that justify this change. Security protocols for accidental releases are also discussed. In summary, the 12th rule of ''Green Chemistry'' (Inherently Safer Chemistry for Accident Prevention) should be followed: the form of a substance used in a chemical process (Movement of Hazardous Chemicals) should be chosen to minimize the potential for chemical accidents, including releases.

A method and apparatus for preparing the storage of noxious substances, in particular radioactive substances

International Nuclear Information System (INIS)

1974-01-01

The invention relates to the storage of radioactive substances. It deals with a method for storing a substance, in particular a noxious or radioactive substance, comprising trapping said substance in a solid substance by bombarding said solid substance with ions of the above substance, so that the latter reaches a certain concentration level in the solid substance. This is applicable to the storage of radioactive wastes [fr

Elimination of micropollutants and hazardous substances at the source in the chemical and pharmaceutical industry.

Science.gov (United States)

Blöcher, C

2007-01-01

Industrial wastewater, especially from chemical and pharmaceutical production, often contains substances that need to be eliminated before being discharged into a biological treatment plant and following water bodies. This can be done within the production itself, in selected waste water streams or in a central treatment plant. Each of these approaches has certain advantages and disadvantages. Furthermore, a variety of wastewater treatment processes exist that can be applied at each stage, making it a challenging task to choose the best one in economic and ecological terms. In this work a general approach for that and examples from practice are discussed.

Substance abuse: a national survey of Canadian residency program directors and site chiefs at university-affiliated anesthesia departments.

Science.gov (United States)

Boulis, Sherif; Khanduja, P Kristina; Downey, Kristi; Friedman, Zeev

2015-09-01

The abuse of substances available to anesthesiologists in their workspace is a potentially lethal occupational hazard. Our primary objective was to define the prevalence of substance abuse cases among Canadian anesthesiologists at university-affiliated hospitals. Our secondary aim was to describe the current management of confirmed cases, rehabilitation procedures being offered, and preventative strategies being employed. We conducted a cross-sectional electronic survey of all Canadian anesthesia residency program directors and site chiefs at university-affiliated hospitals. Data analysis was performed using descriptive statistics. The survey response rate was 54% (53/98). Substance abuse was reported as 1.6% for residents and 0.3% for clinical fellows over a ten-year period ending in June 2014. Fentanyl was abused in nine of 24 reported cases. At present, one of 22 respondents (4.5%) reported a formal education program on substance abuse for faculty members, and 72% described mandatory education for residents. The majority of participants did not perceive substance abuse as a growing problem. Seventy-one percent of respondents indicated that methods for controlled-drug handling had changed in the previous ten years; however, 66% did not think that the incidence of controlled substance abuse could be decreased further by more stringent measures. Only 21% of respondents supported the introduction of random urine drug testing. The prevalence of substance abuse among Canadian anesthesiologists and the substances abused appear comparable with data from the United States, with residents being the group most often affected. Early recognition and treatment of chemically dependent anesthesiologists remain imperfect.

Apparatus and methods for monitoring the concentrations of hazardous airborne substances, especially lead

Science.gov (United States)

Zaromb, Solomon

2004-07-13

Air is sampled at a rate in excess of 100 L/min, preferably at 200-300 L/min, so as to collect therefrom a substantial fraction, i.e., at least 20%, preferably 60-100%, of airborne particulates. A substance of interest (analyte), such as lead, is rapidly solubilized from the the collected particulates into a sample of liquid extractant, and the concentration of the analyte in the extractant sample is determined. The high-rate air sampling and particulate collection may be effected with a high-throughput filter cartridge or with a recently developed portable high-throughput liquid-absorption air sampler. Rapid solubilization of lead is achieved by a liquid extractant comprising 0.1-1 M of acetic acid or acetate, preferably at a pH of 5 or less and preferably with inclusion of 1-10% of hydrogen peroxide. Rapid determination of the lead content in the liquid extractant may be effected with a colorimetric or an electroanalytical analyzer.

Individual risk evaluation and interventions for mitigation in the transportation of hazardous goods: a case study

Directory of Open Access Journals (Sweden)

Rada Elena Cristina

2017-01-01

Full Text Available The transport of hazardous substances is an economic activity essential for goods’ transference chain. However, the risk in transporting hazardous materials is related to the occur of accidents causing environmental damages and public health dangerous consequences. A quite recent Italian example is the Viareggio accident (2010, which involved a train with tank cars containing liquefied petroleum gas (LPG which caused more than thirty deaths. This paper describes the safety state in the Varese district (an area of northern Italy with a very high population density and industrial activities, with the aim at comparing the current situation (considering the risks due to the transportation of hazardous materials on the main motorways and main national roads with a potential scenario that introduces a few mitigating interventions, such as a partial conversion from road haulage to rail transport. This comparison can be accomplished by developing the existing intermodal platforms and implementing new ones in strategic areas.

Environmental and health hazard ranking and assessment of plastic polymers based on chemical composition

Energy Technology Data Exchange (ETDEWEB)

Lithner, Delilah, E-mail: delilah.lithner@gmail.com; Larsson, Ake; Dave, Goeran

2011-08-15

Plastics constitute a large material group with a global annual production that has doubled in 15 years (245 million tonnes in 2008). Plastics are present everywhere in society and the environment, especially the marine environment, where large amounts of plastic waste accumulate. The knowledge of human and environmental hazards and risks from chemicals associated with the diversity of plastic products is very limited. Most chemicals used for producing plastic polymers are derived from non-renewable crude oil, and several are hazardous. These may be released during the production, use and disposal of the plastic product. In this study the environmental and health hazards of chemicals used in 55 thermoplastic and thermosetting polymers were identified and compiled. A hazard ranking model was developed for the hazard classes and categories in the EU classification and labelling (CLP) regulation which is based on the UN Globally Harmonized System. The polymers were ranked based on monomer hazard classifications, and initial assessments were made. The polymers that ranked as most hazardous are made of monomers classified as mutagenic and/or carcinogenic (category 1A or 1B). These belong to the polymer families of polyurethanes, polyacrylonitriles, polyvinyl chloride, epoxy resins, and styrenic copolymers. All have a large global annual production (1-37 million tonnes). A considerable number of polymers (31 out of 55) are made of monomers that belong to the two worst of the ranking model's five hazard levels, i.e. levels IV-V. The polymers that are made of level IV monomers and have a large global annual production (1-5 million tonnes) are phenol formaldehyde resins, unsaturated polyesters, polycarbonate, polymethyl methacrylate, and urea-formaldehyde resins. This study has identified hazardous substances used in polymer production for which the risks should be evaluated for decisions on the need for risk reduction measures, substitution, or even phase out

Prevalence of substance abuse among regular degree health science students in Sheba University College in Mekelle Town, Tigray - Ethiopia.

Science.gov (United States)

Hagos, Esietu Gebregazabher; Asfeha, Gebrekidan Gebregzabher; Berihu, Birhane Alem

2016-01-01

Substance abuse (SA) refers to the harmful or hazardous use of psychoactive substances, including alcohol and illicit drugs. The most common substances which are usually abused are alcohol and tobacco. Herein, we assessed the prevalence of SA among regular degree health science students of the Sheba University College (SUC). A cross-sectional survey was carried out among 1076 SUC students using self-administered structured questionnaire. The simple sampling technique was used to select students. Descriptive statistics, bivariate, and multivariate analysis were done. The overall prevalence of "ever used substance" for at least one was 45.5%. The most commonly used drugs in descending order were alcohol (25.1%), cigarette (11.4%), and khat (9.2%). Male participants, urban setting, peer pressure, personal pleasure, and academic dissatisfaction and pocket money were highly associated with SA. This study showed a lower magnitude (45.6% ever use and 21% still using) of SA among students' compared to other studies. Even if a considerable decrease in SA among study subjects, the creation of awareness and health education should be continued to fully combat the problem of abuse.

Familial confounding of the association between maternal smoking during pregnancy and offspring substance use and problems.

Science.gov (United States)

D'Onofrio, Brian M; Rickert, Martin E; Langström, Niklas; Donahue, Kelly L; Coyne, Claire A; Larsson, Henrik; Ellingson, Jarrod M; Van Hulle, Carol A; Iliadou, Anastasia N; Rathouz, Paul J; Lahey, Benjamin B; Lichtenstein, Paul

2012-11-01

Previous epidemiological, animal, and human cognitive neuroscience research suggests that maternal smoking during pregnancy (SDP) causes increased risk of substance use/problems in offspring. To determine the extent to which the association between SDP and offspring substance use/problems depends on confounded familial background factors by using a quasi-experimental design. We used 2 separate samples from the United States and Sweden. The analyses prospectively predicted multiple indices of substance use and problems while controlling for statistical covariates and comparing differentially exposed siblings to minimize confounding. Offspring of a representative sample of women in the United States (sample 1) and the total Swedish population born during the period from January 1, 1983, to December 31, 1995 (sample 2). Adolescent offspring of the women in the National Longitudinal Survey of Youth 1979 (n = 6904) and all offspring born in Sweden during the 13-year period (n = 1,187,360). Self-reported adolescent alcohol, cigarette, and marijuana use and early onset (before 14 years of age) of each substance (sample 1) and substance-related convictions and hospitalizations for an alcohol- or other drug-related problem (sample 2). The same pattern emerged for each index of substance use/problems across the 2 samples. At the population level, maternal SDP predicted every measure of offspring substance use/problems in both samples, ranging from adolescent alcohol use (hazard ratio [HR](moderate), 1.32 [95% CI, 1.22-1.43]; HR(high), 1.33 [1.17-1.53]) to a narcotics-related conviction (HR(moderate), 2.23 [2.14-2.31]; HR(high), 2.97 [2.86-3.09]). When comparing differentially exposed siblings to minimize genetic and environmental confounds, however, the association between SDP and each measure of substance use/problems was minimal and not statistically significant. The association between maternal SDP and offspring substance use/problems is likely due to familial background

Regulations on the prevention of ionizing radiation hazards

International Nuclear Information System (INIS)

1977-01-01

In accordance with the Law on Health and Safety at Work (Law No. 57, 1972) the regulations require any employer who runs an undertaking performing radiation-related works (hereinafter called ''the employer'') to protect his employees from ionizing radiation hazards. Chapter 1 (general provisions) gives the definitions of such technical terms as the ionizing radiations, the radioactive substances and the radiation-related works. Chapter 2 defines the controlled areas and the tolerance doses of radiation exposures. The controlled areas mean the areas within which the employer is required: to control the radiation doses; to prohibit access thereto of anyone other than who are necessary there; not to cause any person who is engaged there in the radiation-related works to be exposed to the radiation dose more than 3 rem within 3 months and any other person who has access regularly thereto to be exposed to more than 1.5 rem within a year; and to build special rooms for containing prescribed radiation-related appliances or apparatus. Chapter 4 requires the employer to build special working rooms for the treatment of such radioactive substances that are not sealed up tightly, and also prescribes the requirements concerning the construction of such rooms. (Matsushima, A.)

Effect of BCAA intake during endurance exercises on fatigue substances, muscle damage substances, and energy metabolism substances.

Science.gov (United States)

Kim, Dong-Hee; Kim, Seok-Hwan; Jeong, Woo-Seok; Lee, Ha-Yan

2013-12-01

The increase rate of utilization of branched-chain amino acids (BCAA) by muscle is reduced to its plasma concentration during prolonged exercise leading to glycogen. BCAA supplementation would reduce the serum activities of intramuscular enzymes associated with muscle damage. To examine the effects of BCAA administration on fatigue substances (serotonin, ammonia and lactate), muscle damage substances (CK and LDH) and energy metabolism substances (FFA and glucose) after endurance exercise. Subjects (n = 26, college-aged males) were randomly divided into an experimental (n = 13, EXP) and a placebo (n = 13, CON) group. Subjects both EXP and CON performed a bout of cycle training (70% VO2max intensity) to exhaustion. Subject in the EXP were administrated BCAA (78ml/kg·w) prior to the bout of cycle exercise. Fatigue substances, muscle damage substances and energy metabolism substances were measured before ingesting BCAAs and placebos, 10 min before exercise, 30 min into exercise, immediately after exercise, and 30 min after exercise. Data were analyzed by two-way repeated measure ANCOVA, correlation and statistical significance was set at p BCAA decreased serum concentrations of the intramuscular enzymes as CK and LDH following exhaustive exercise. This observation suggests that BCAA supplementation may reduce the muscle damage associated with endurance exercise.

Obtention to the methodology for evaluation to the confirmation of the hazardous wastes safety isolation

International Nuclear Information System (INIS)

Peralta, J.L.; Gil, R.; Castillo, R.; Leyva, D.

2003-01-01

Taking into account, the practical experience of the safety assessment in the radioactive wastes management, the International Atomic Energy Agency (IAEA) recommendations in this topics, the norms and national and international legislation about noxious substances to the environment and their restriction limits, the best international practices and approaches of isolation hazardous wastes sites, a Methodology is developed (Cuba particular conditions) to obtaining and/or confirmation of the hazardous wastes safety isolation, as a tool able to carry out the assessment of facilities to build and all installation and/or place where hazardous wastes isolated from the environment. The Methodology, embraces the evaluation of technical, economic and social topics, allowing to develop an integral safety assessment which allows to estimate the environment possible impact for hazardous waste isolation (radioactive and non radioactive); Just are shown in this paper the selection approaches for the obtaining and/or evaluation of the best site, the steps description to continue for the definition of the main scenarios and the models to take into account in the valuation of the possible liberation and pathway to the environment of the non radioactive pollutants. The main contribution of this Methodology resides in the creation of a scientific-technique necessary guide for the evident demand of carrying out the most organized, effective and hazardous wastes safety management

Laser Cutting of Carbon Fiber Reinforced Plastics - Investigation of Hazardous Process Emissions

Science.gov (United States)

Walter, Juergen; Hustedt, Michael; Staehr, Richard; Kaierle, Stefan; Jaeschke, Peter; Suttmann, Oliver; Overmeyer, Ludger

Carbon fiber reinforced plastics (CFRP) show high potential for use in lightweight applications not only in aircraft design, but also in the automotive or wind energy industry. However, processing of CFRP is complex and expensive due to their outstanding mechanical properties. One possibility to manufacture CFRP structures flexibly at acceptable process speeds is high-power laser cutting. Though showing various advantages such as contactless energy transfer, this process is connected to potentially hazardous emission of respirable dust and organic gases. Moreover, the emitted particles may be fibrous, thus requiring particular attention. Here, a systematic analysis of the hazardous substances emitted during laser cutting of CFRP with thermoplastic and thermosetting matrix is presented. The objective is to evaluate emission rates for the total particulate and gaseous fractions as well as for different organic key components. Furthermore, the influence of the laser process conditions shall be assessed, and first proposals to handle the emissions adequately are made.

Conceptual design report, Hazardous Materials Management and Emergency Response (HAMMER) Training Center

Energy Technology Data Exchange (ETDEWEB)

Kelly, K.E. [Westinghouse Hanford Co., Richland, WA (United States)

1994-11-09

For the next 30 years, the main activities at the US Department of Energy (DOE) Hanford Site will involve the management, handling, and cleanup of toxic substances. If the DOE is to meet its high standards of safety, the thousands of workers involved in these activities will need systematic training appropriate to their tasks and the risks associated with these tasks. Furthermore, emergency response for DOE shipments is the primary responsibility of state, tribal, and local governments. A collaborative training initiative with the DOE will strengthen emergency response at the Hanford Site and within the regional communities. Local and international labor has joined the Hazardous Materials Management and Emergency Response (HAMMER) partnership, and will share in the HAMMER Training Center core programs and facilities using their own specialized trainers and training programs. The HAMMER Training Center will provide a centralized regional site dedicated to the training of hazardous material, emergency response, and fire fighting personnel.

Conceptual design report, Hazardous Materials Management and Emergency Response (HAMMER) Training Center

International Nuclear Information System (INIS)

Kelly, K.E.

1994-01-01

For the next 30 years, the main activities at the US Department of Energy (DOE) Hanford Site will involve the management, handling, and cleanup of toxic substances. If the DOE is to meet its high standards of safety, the thousands of workers involved in these activities will need systematic training appropriate to their tasks and the risks associated with these tasks. Furthermore, emergency response for DOE shipments is the primary responsibility of state, tribal, and local governments. A collaborative training initiative with the DOE will strengthen emergency response at the Hanford Site and within the regional communities. Local and international labor has joined the Hazardous Materials Management and Emergency Response (HAMMER) partnership, and will share in the HAMMER Training Center core programs and facilities using their own specialized trainers and training programs. The HAMMER Training Center will provide a centralized regional site dedicated to the training of hazardous material, emergency response, and fire fighting personnel

Treatment of substance misuse in older women: using a brief intervention model.

Science.gov (United States)

Finfgeld-Connett, Deborah L

2004-08-01

Alcohol and benzodiazepine misuse is a significant problem in older women for a number of reasons such as physiological changes, outdated prescribing practices, and failure to identify hazardous use. In addition, treatment barriers involving the health-care system, conflicting information, and ageism also exist. Substance misuse among older women is predicted to become a bigger problem as the baby boom generation ages. Brief interventions that consist of assessment, feedback, responsibility, advice, menu, empathy, and self-efficacy, or A-FRAMES, have the potential to reduce alcohol and benzodiazepine misuse among older women in a cost-effective manner.

Comparative alternative materials assessment to screen toxicity hazards in the life cycle of CIGS thin film photovoltaics

Energy Technology Data Exchange (ETDEWEB)

Eisenberg, Daniel A.; Yu, Mengjing; Lam, Carl W. [University of California, Davis, 1 Shields Avenue, Davis, CA 95616 (United States); Ogunseitan, Oladele A. [University of California, Irvine, Irvine, CA 92697 (United States); Schoenung, Julie M., E-mail: jmschoenung@ucdavis.edu [University of California, Davis, 1 Shields Avenue, Davis, CA 95616 (United States)

2013-09-15

Highlights: • Comparative alternatives assessment of thin film manufacturing technologies. • Development of chemical alternatives assessment in a life cycle context. • Screening of manufacturing and solar cell hazardous substances simultaneously. -- Abstract: Copper–indium–gallium–selenium–sulfide (CIGS) thin film photovoltaics are increasingly penetrating the market supply for consumer solar panels. Although CIGS is attractive for producing less greenhouse gas emissions than fossil-fuel based energy sources, CIGS manufacturing processes and solar cell devices use hazardous materials that should be carefully considered in evaluating and comparing net environmental benefits of energy products. Through this research, we present a case study on the toxicity hazards associated with alternative materials selection for CIGS manufacturing. We applied two numeric models, The Green Screen for Safer Chemicals™ and the Toxic Potential Indicator. To improve the sensitivity of the model outputs, we developed a novel, life cycle thinking based hazard assessment method that facilitates the projection of hazards throughout material life cycles. Our results show that the least hazardous CIGS solar cell device and manufacturing protocol consist of a titanium substrate, molybdenum metal back electrode, CuInS{sub 2} p-type absorber deposited by spray pyrolysis, ZnS buffer deposited by spray ion layer gas reduction, ZnO:Ga transparent conducting oxide (TCO) deposited by sputtering, and the encapsulant polydimethylsiloxane.

Hazards and hazard combinations relevant for the safety of nuclear power plants

Science.gov (United States)

Decker, Kurt; Brinkman, Hans; Raimond, Emmanuel

2017-04-01

The potential of the contemporaneous impact of different, yet causally related, hazardous events and event cascades on nuclear power plants is a major contributor to the overall risk of nuclear installations. In the aftermath of the Fukushima accident, which was caused by a combination of severe ground shaking by an earthquake, an earthquake-triggered tsunami and the disruption of the plants from the electrical grid by a seismically induced landslide, hazard combinations and hazard cascades moved into the focus of nuclear safety research. We therefore developed an exhaustive list of external hazards and hazard combinations which pose potential threats to nuclear installations in the framework of the European project ASAMPSAE (Advanced Safety Assessment: Extended PSA). The project gathers 31 partners from Europe, North Amerika and Japan. The list comprises of exhaustive lists of natural hazards, external man-made hazards, and a cross-correlation matrix of these hazards. The hazard list is regarded comprehensive by including all types of hazards that were previously cited in documents by IAEA, the Western European Nuclear Regulators Association (WENRA), and others. 73 natural hazards and 24 man-made external hazards are included. Natural hazards are grouped into seismotectonic hazards, flooding and hydrological hazards, extreme values of meteorological phenomena, rare meteorological phenomena, biological hazards / infestation, geological hazards, and forest fire / wild fire. The list of external man-made hazards includes industry accidents, military accidents, transportation accidents, pipeline accidents and other man-made external events. The large number of different hazards results in the extremely large number of 5.151 theoretically possible hazard combinations (not considering hazard cascades). In principle all of these combinations are possible to occur by random coincidence except for 82 hazard combinations that - depending on the time scale - are mutually

Association between alcohol, cannabis, and other illicit substance abuse and risk of developing schizophrenia: a nationwide population based register study.

Science.gov (United States)

Nielsen, S M; Toftdahl, N G; Nordentoft, M; Hjorthøj, C

2017-07-01

Several studies have examined whether use of substances can cause schizophrenia. However, due to methodological limitations in the existing literature (e.g. selection bias and lack of adjustment of co-abuse) uncertainties still remain. We aimed to investigate whether substance abuse increases the risk of developing schizophrenia, addressing some of these limitations. The longitudinal, nationwide Danish registers were linked to establish a cohort of 3 133 968 individuals (105 178 673 person-years at risk), identifying 204 505 individuals diagnosed with substance abuse and 21 305 diagnosed with schizophrenia. Information regarding substance abuse was extracted from several registers and did not include psychotic symptoms caused by substance abuse in the definition. This resulted in a large, generalizable sample of exposed individuals. The data was analysed using Cox regression analyses, and adjusted for calendar year, gender, urbanicity, co-abuse, other psychiatric diagnosis, parental substance abuse, psychiatric history, immigration and socioeconomic status. A diagnosis of substance abuse increased the overall risk of developing schizophrenia [hazard ratio (HR) 6.04, 95% confidence interval (CI) 5.84-6.26]. Cannabis (HR 5.20, 95% CI 4.86-5.57) and alcohol (HR 3.38, 95% CI 3.24-3.53) presented the strongest associations. Abuse of hallucinogens (HR 1.86, 95% CI 1.43-2.41), sedatives (HR 1.68, 95% CI 1.49-1.90), and other substances (HR 2.85, 95% CI 2.58-3.15) also increased the risk significantly. The risk was found to be significant even 10-15 years subsequent to a diagnosis of substance abuse. Our results illustrate robust associations between almost any type of substance abuse and an increased risk of developing schizophrenia later in life.

Sexual orientation, substance use behaviors and substance dependence in the United States

Science.gov (United States)

McCabe, Sean Esteban; Hughes, Tonda L.; Bostwick, Wendy B.; West, Brady T.; Boyd, Carol J.

2009-01-01

Aims To assess past-year prevalence rates of substance use behaviors and substance dependence across three major dimensions of sexual orientation (identity, attraction, and behavior) in a large national sample of adult women and men in the United States. Design Data were collected from structured diagnostic face-to-face interviews using the Alcohol Use Disorder and Associated Disabilities Interview Schedule DSM-IV Version (AUDADIS-IV). Setting Prevalence estimates were based on data collected from the 2004–2005 (Wave 2) National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). Participants A large national sample of 34,653 adults aged 20 years and older: 52% female, 71% White, 12% Hispanic, 11% African American, 4% Asian, and 2% Native American or other racial/ethnic categories. Findings Approximately 2% of the sample self-identified as lesbian, gay or bisexual; 4% reported at least one lifetime same-sex sexual partner, and 6% reported same-sex sexual attraction. Although non-heterosexual orientation was generally associated with a higher risk of substance use and substance dependence, the majority of sexual minority respondents did not report substance use or meet criteria for DSM-IV substance dependence. There was considerable variation in substance use outcomes across sexual orientation dimensions; these variations were more pronounced among women than among men. Conclusions Results support previous research findings of heightened risk of substance use and substance dependence among some sexual minority groups and point to the need for research that examines reasons for such differences. Results also highlight important gender differences and question previous findings indicating uniformly higher risk for substance dependence among sexual minorities. Risks appear to vary based on gender and how sexual orientation is defined. Findings have implications for prevention and intervention efforts that more effectively target subgroups at greatest

Hazard perception in traffic. [previously knows as: Hazard perception.

NARCIS (Netherlands)

2008-01-01

Hazard perception is an essential part of the driving task. There are clear indications that insufficient skills in perceiving hazards play an important role in the occurrence of crashes, especially those involving novice drivers. Proper hazard perception not only consists of scanning and perceiving

Evaluating and Addressing Potential Hazards of Fuel Tanks Surviving Atmospheric Reentry

Science.gov (United States)

Kelley, Robert L.; Johnson, Nicholas L.

2011-01-01

In order to ensure reentering spacecraft do not pose an undue risk to the Earth's population it is important to design satellites and rocket bodies with end of life considerations in mind. In addition to considering the possible consequences of deorbiting a vehicle, consideration must also be given to the possible risks associated with a vehicle failing to become operational or reach its intended orbit. Based on recovered space debris and numerous reentry survivability analyses, fuel tanks are of particular concern in both of these considerations. Most spacecraft utilize some type of fuel tank as part of their propulsion system. These fuel tanks are most often constructed using stainless steel or titanium and are filled with potentially hazardous substances such as hydrazine and nitrogen tetroxide. For a vehicle which has reached its scheduled end of mission the contents of the tanks are typically depleted. In this scenario the use of stainless steel and titanium results in the tanks posing a risk to people and property do to the high melting point and large heat of ablation of these materials leading to likely survival of the tank during reentry. If a large portion of the fuel is not depleted prior to reentry, there is the added risk of hazardous substance being released when the tank impact the ground. This paper presents a discussion of proactive methods which have been utilized by NASA satellite projects to address the risks associated with fuel tanks reentering the atmosphere. In particular it will address the design of a demiseable fuel tank as well as the evaluation of off the shelf designs which are selected to burst during reentry.

Risk assessment of major hazards and its application in urban planning: a case study.

Science.gov (United States)

Zhou, Yafei; Liu, Mao

2012-03-01

With the rapid development of industry in China, the number of establishments that are proposed or under construction is increasing year by year, and many are industries that handle flammable, explosive, toxic, harmful, and dangerous substances. Accidents such as fire, explosion, and toxic diffusion inevitably happen. Accidents resulting from these major hazards in cities cause a large number of casualties and property losses. It is increasingly important to analyze the risk of major hazards in cities realistically and to suitably plan and utilize the surrounding land based on the risk analysis results, thereby reducing the hazards. A theoretical system for risk assessment of major hazards in cities is proposed in this article, and the major hazard risk for the entire city is analyzed quantitatively. Risks of various major accidents are considered together, superposition effect is analyzed, individual risk contours of the entire city are drawn out, and the level of risk in the city is assessed using "as low as reasonably practicable" guidelines. After the entire city's individual risk distribution is obtained, risk zones are divided according to corresponding individual risk value of HSE, and land-use planning suggestions are proposed. Finally, a city in China is used as an example to illustrate the risk assessment process of the city's major hazard and its application in urban land-use planning. The proposed method has a certain theoretical and practical significance in establishing and improving risk analysis of major hazard and urban land-use planning. On the one hand, major urban public risk is avoided; further, the land is utilized in the best possible way in order to obtain the maximum benefit from its use. © 2011 Society for Risk Analysis.

Environmental education for hazardous waste management and risk reduction in laboratories

Directory of Open Access Journals (Sweden)

Tomas Rafael Pierre Martinez

2013-10-01

Full Text Available The University laboratories are places where teaching, extension and research activities are develop, which harmful substances are manipulated and hazardous waste are generated, the lack of information about this makes them an inadequate provision causing human health and environmental risks. This research proposes the implementation of environmental education as an alternative for waste management and safety in the University of Magdalena laboratories. Applying a series of polls showed the effectiveness with efficiency or assertively rises at 30% cognitive level during the process. It recommends to obtain better results is necessary evaluate the ethic component.  

Identification of Potential Hazard using Hazard Identification and Risk Assessment

Science.gov (United States)

Sari, R. M.; Syahputri, K.; Rizkya, I.; Siregar, I.

2017-03-01

This research was conducted in the paper production’s company. These Paper products will be used as a cigarette paper. Along in the production’s process, Company provides the machines and equipment that operated by workers. During the operations, all workers may potentially injured. It known as a potential hazard. Hazard identification and risk assessment is one part of a safety and health program in the stage of risk management. This is very important as part of efforts to prevent occupational injuries and diseases resulting from work. This research is experiencing a problem that is not the identification of potential hazards and risks that would be faced by workers during the running production process. The purpose of this study was to identify the potential hazards by using hazard identification and risk assessment methods. Risk assessment is done using severity criteria and the probability of an accident. According to the research there are 23 potential hazard that occurs with varying severity and probability. Then made the determination Risk Assessment Code (RAC) for each potential hazard, and gained 3 extreme risks, 10 high risks, 6 medium risks and 3 low risks. We have successfully identified potential hazard using RAC.

Impact of rurality and substance use on young people at ultra high risk for psychosis.

Science.gov (United States)

Stain, Helen J; Halpin, Sean A; Baker, Amanda L; Startup, Mike; Carr, Vaughan J; Schall, Ulrich; Crittenden, Kylie; Clark, Vanessa; Lewin, Terry J; Bucci, Sandra

2017-07-26

Longitudinal research into early intervention for youth at ultra high risk (UHR) for psychosis demonstrates beneficial outcomes including increased treatment compliance and greater participation in education and the workforce. Despite known barriers for rural youth accessing mental health services, research comparing urban and rural UHR youth is lacking. The study included an examination of the impact of substance use on functioning of UHR youth. Youth aged 12 to 25 years were recruited from the urban area of Newcastle or the rural area of Orange, New South Wales, Australia, and identified as UHR by the Comprehensive Assessment of At Risk Mental States. Rural and urban youth were compared on clinical profiles, social and occupational functioning and substance use. The rural youth showed different help-seeking behaviours and had greater functional impairment than urban youth. Substance use was common across the sample of 57 youth (mean age 16.5 years, 56% female) and a history of hazardous substance use was associated with higher levels of depression. Rural youth (n = 32) were more likely than urban youth to be taking antidepressants at baseline (44% compared with 16%). Different patterns of help seeking by rural UHR youth suggest a need for greater access to psychosis informed primary care early intervention services. Interventions should target functional decline to prevent adverse outcomes such as reduced community participation and unemployment. In addition, interventions for substance use should be a priority for UHR youth, who should also be screened and monitored for depressive symptoms and treated for depression if indicated. © 2017 John Wiley & Sons Australia, Ltd.

The effectiveness of removing precursors of chlorinated organic substances in pilot water treatment plant

Science.gov (United States)

Wolska, Małgorzata; Szerzyna, Sławomir; Machi, Justyna; Mołczan, Marek; Adamski, Wojciech; Wiśniewski, Jacek

2017-11-01

The presence of organic substances in the water intaken for consumption could be hazardous to human health due to the potential formation of disinfection by-products (TOX). The study were carried out in the pilot surface water treatment system consisting of coagulation, sedimentation, filtration, ozonation, adsorption and disinfection. Due to continuous operation of the system and interference with the parameters of the processes it was possible not only assess the effectiveness of individual water treatment processes in removing TOX, but also on factors participating on the course of unit processes.

Concept of assistance of the Federal Office for Rdiation Protection with regard to serious cases of prevention of nuclear hazards

International Nuclear Information System (INIS)

Becker, D.E.

1998-01-01

For the defence against the threats through radioactive substances, a general concept is presently being elaborated under the overall control of the Federal Government. A number of competent organisations are involved in this, for example the Federal Office of Criminal Investigation, the Federal Armed Forces, and the Federal Office for Radiation Protection. In Germany, the 16 Federal States are responsible for the prevention of nuclear hazards. In the case of hazards through radioactive material, experts from the competent radiation protection authorities are consulted. For serious cases of prevention of nuclear hazards (nuclear fuels, criticality, danger of dispersion), the Federal Office for Radiation Protection - a subordinate authority of the Federal Ministry for the Environment, Nature Conservation and Nuclear Safety responsible for radiation protection - was given order to elaborate a concept for assistance to those Federal States. This concept is presented in the following. (author)

HPA axis response to psychological stress and treatment retention in residential substance abuse treatment: a prospective study.

Science.gov (United States)

Daughters, Stacey B; Richards, Jessica M; Gorka, Stephanie M; Sinha, Rajita

2009-12-01

Substance abuse treatment programs are often characterized by high rates of premature treatment dropout, which increases the likelihood of relapse to drug use. Negative reinforcement models of addiction emphasize an individual's inability to tolerate stress as a key factor for understanding poor substance use treatment outcomes, and evidence indicates that dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis contributes to an individual's inability to respond adaptively to stress. The aim of the current study was to examine whether HPA axis response to stress is predictive of treatment retention among a sample of drug users in residential substance abuse treatment. Prospective study assessing treatment retention among 102 individuals enrolled in residential substance abuse treatment. Participants completed two computerized stress tasks, and HPA axis response to stress was measured via salivary cortisol at five time points from baseline (pre-stress) to 30 min post-stress exposure. The main outcome measures were treatment dropout (categorical) and total number of days in treatment (continuous). A significantly higher salivary cortisol response to stress was observed in treatment dropouts compared to treatment completers. Further, Cox proportional hazards survival analyses indicated that a higher peak cortisol response to stress was associated with a shorter number of days to treatment dropout. Results indicate that a higher salivary cortisol level in response to stress is associated with an inability to remain in substance abuse treatment. These findings are the first to document a biological marker of stress as a predictor of substance abuse treatment dropout, and support the development and implementation of treatments targeting this vulnerability.

Royal Order of 27 July 1966 relating to the reciprocal recognition of licences for the import, transport, transit, and distribution of radioactive substances between the countries of the Benelux Economic Union

International Nuclear Information System (INIS)

1966-01-01

This Royal Order made taking into account the 1958 Act on protection of the population against the hazards of ionizing radiations, the 1963 Royal Order embodying the general regulations on protection of the population and workers against the hazards of ionizing radiations and the 1966 recommendation of the Committee of Ministers of the Benelux Economic Union lays down that, notwithstanding Section 38 and 57 of the 1963 Royal Order, licences for the import, transport and transit of radioactive substances or devices containing them which are issued by the competent authorities of the Netherlands or Luxembourg are valid in Belgium. Also, a Belgia distributor of such substances or devices containing them must ensure that a consignee residing in either of these countries holds the licences required by his national law. (NEA) [fr

Tracking and mapping of spatiotemporal quantities using unicellular swarm intelligence visualisation of invisible hazardous substances using unicellular swarm intelligence

CERN Document Server

Oyekan, John Oluwagbemiga

2016-01-01

The book discusses new algorithms capable of searching for, tracking, mapping and providing a visualization of invisible substances. It reports on the realization of a bacterium-inspired robotic controller that can be used by an agent to search for any environmental spatial function such as temperature or pollution. Using the parameters of a mathematical model, the book shows that it is possible to control the exploration, exploitation and sensitivity of the agent. This feature sets the work apart from the usual method of applying the bacterium behavior to robotic agents. The book also discusses how a computationally tractable multi-agent robotic controller was developed and used to track as well as provide a visual map of a spatio-temporal distribution of a substance. On the one hand, this book provides biologists and ecologists with a basis to perform simulations related to how individual organisms respond to spatio-temporal factors in their environment as well as predict and analyze the behavior of organis...

Regulating specific organic substances and heavy metals in industrial wastewater discharged to municipal wastewater treatment plants

DEFF Research Database (Denmark)

Grüttner, Henrik; Munk, L.; Pedersen, F.

1994-01-01

Due to the extension of wastewater treatment plants to nutrient removal and the development towards reuse of sludge m agriculture, new guidelines for regulating industrial discharges m Denmark were needed. The paper describes how a concept for regulating the discharge of specific organic substances...... substances, present knowledge of fate and effects in biological treatment plants is too scarce to underpin the setting of general standards. Therefore, it has been decided to base the developed priority system on the data used in the EEC-system for classification of hazardous chemicals. This includes ready...... degradability, defined by the OECD-test, bio-sorption and bio-accumulation, defined by the octanol/water distribution coefficient and toxic effects on water organisms. Several potential effects of seven heavy metals have been evaluated, and the most critical effects were found to be the quality criteria...

Prevalence of Substance Abuse among Senior Secondary Students in Mainland Local Government, Lagos

Directory of Open Access Journals (Sweden)

George N. Ani

2014-01-01

Full Text Available Background: Substance abuse refers to the harmful or hazardous use of psychoactive substances, including alcohol and illicit drugs. Use of drugs among adolescents is a global phenomenon eating deep into the fabrics of our society. Students are most vulnerable at this transformative stage in their life. Available report indicates that Nigeria is currently the highest consumer of cannabis and amphetamine in Africa. What is the prevalence of this abuse by students? Methodology: This research was a cross sectional descriptive design to identify the prevalence of substance abuse among students in public senior secondary schools in Mainland Local Government, Lagos. A sample size of two hundred and sixty two was determined and used from randomly selected five out of the nine public schools identified. Multi stage sampling (including simple random and systematic sampling and probability proportional to size methods were usefully employed in scientific selection of 262 samples and subsequent data collection in a total sample frame of 1,938 students. Self-administered questionnaire consisting of open and close-ended questions generated using research objectives was used in data collection. Result: It identified that 19.5% had smoked cigarette once or more in their lifetime. 77.2% had used alcohol once or more in a life time while 7.7% used marijuana, 8.4% tranquilizers and 1.9% cocaine all in a life time respectively. Conclusion: It recommended strict regulation of alcohol and tobacco products import and use in public places as well as aggressive dissemination of information on the dangers of substance use and abuse.

An evaluation of organic substance fraction removal during ion exchange with Miex-DOC resin.

Science.gov (United States)

Wolska, Małgorzata

2015-07-01

In this study, the usefulness of Miex-DOC resin in eliminating organic substances and their fractions from water sources for drinking water was evaluated. The objects of study were samples from three surface water sources and one infiltration water source taken at water treatment plants before treatment in technical conditions. In particular, the effectiveness of removing biodegradable and non-biodegradable fractions as a function of resin dosages and water-resin contact times was evaluated. The ion exchange process with the Miex-DOC resin achieved a high effectiveness in removing aromatic non-biodegradable organic substances, and therefore a reduction in UV254 absorbance. The biodegradable fraction is much less susceptible to removal yet its removal effectiveness allows for a significant reduction in hazards connected with secondary microorganism development. The results of this study indicate the possibility of using ion exchange with the Miex-DOC resin for effective removal of disinfection by-product precursors.

Peer Substance Use and Homelessness Predicting Substance Abuse from Adolescence Through Early Adulthood

OpenAIRE

Tompsett, Carolyn J.; Domoff, Sarah E.; Toro, Paul A.

2013-01-01

Adolescents who experience homelessness are at higher risk for abusing substances, and for being exposed to substance-using peers. The current study used a longitudinal design to track substance abuse, affiliation with substance-using peers, and episodes of homelessness among a sample of 223 adolescents who were homeless at thebaseline data collection and 148 adolescents who were housed at baseline. Participants were interviewed at six waves over 6.5 years, covering an age rang...

Why the toxic substances control act needs an overhaul, and how to strengthen oversight of chemicals in the interim.

Science.gov (United States)

Vogel, Sarah A; Roberts, Jody A

2011-05-01

The Toxic Substances Control Act gives the Environmental Protection Agency (EPA) the authority to regulate industrial chemicals not covered by other statutes. Today there are more than 83,000 such chemicals. However, the law is widely perceived as weak and outdated, and various stakeholders have called for its reform, citing the EPA's inability to regulate the use of asbestos, among other substances. We analyze the flaws in the act and suggest ways in which the EPA might better position itself to manage chemical risks and protect the public's health. In addition to the new tools and technologies it is adopting, the agency needs new allies-both inside and outside the government-in its efforts to identify and control hazardous chemicals.

607. Order of 7 December 1989 of the Federal Minister for the Environment, Youth and Family concerning the definition of hazardous wastes

International Nuclear Information System (INIS)

1989-01-01

This Order of the Federal Minister for the Environment, Youth and the Family concerning the definition of hazardous wastes came into effect on 1 January 1990. That definition includes radioactive waste, in terms of the Radiation Protection Act in a list of substances to which the Act of 1989 on the disposal of wastes applies. (NEA)

Applied Prevalence Ratio estimation with different Regression models: An example from a cross-national study on substance use research.

Science.gov (United States)

Espelt, Albert; Marí-Dell'Olmo, Marc; Penelo, Eva; Bosque-Prous, Marina

2016-06-14

To examine the differences between Prevalence Ratio (PR) and Odds Ratio (OR) in a cross-sectional study and to provide tools to calculate PR using two statistical packages widely used in substance use research (STATA and R). We used cross-sectional data from 41,263 participants of 16 European countries participating in the Survey on Health, Ageing and Retirement in Europe (SHARE). The dependent variable, hazardous drinking, was calculated using the Alcohol Use Disorders Identification Test - Consumption (AUDIT-C). The main independent variable was gender. Other variables used were: age, educational level and country of residence. PR of hazardous drinking in men with relation to women was estimated using Mantel-Haenszel method, log-binomial regression models and poisson regression models with robust variance. These estimations were compared to the OR calculated using logistic regression models. Prevalence of hazardous drinkers varied among countries. Generally, men have higher prevalence of hazardous drinking than women [PR=1.43 (1.38-1.47)]. Estimated PR was identical independently of the method and the statistical package used. However, OR overestimated PR, depending on the prevalence of hazardous drinking in the country. In cross-sectional studies, where comparisons between countries with differences in the prevalence of the disease or condition are made, it is advisable to use PR instead of OR.

Criteria and Processes for the Certification of Non-Radioactive Hazardous and Non-Hazardous Wastes

International Nuclear Information System (INIS)

Dominick, J.

2008-01-01

This document details Lawrence Livermore National Laboratory's (LLNL) criteria and processes for determining if potentially volumetrically contaminated or potentially surface contaminated wastes are to be managed as material containing residual radioactivity or as non-radioactive. This document updates and replaces UCRL-AR-109662, Criteria and Procedures for the Certification of Nonradioactive Hazardous Waste (Reference 1), also known as 'The Moratorium', and follows the guidance found in the U.S. Department of Energy (DOE) document, Performance Objective for Certification of Non-Radioactive Hazardous Waste (Reference 2). The 1992 Moratorium document (UCRL-AR-109662) is three volumes and 703 pages. The first volume provides an overview of the certification process and lists the key radioanalytical methods and their associated Limits of Sensitivities. Volumes Two and Three contain supporting documents and include over 30 operating procedures, QA plans, training documents and organizational charts that describe the hazardous and radioactive waste management system in place in 1992. This current document is intended to update the previous Moratorium documents and to serve as the top-tier LLNL institutional Moratorium document. The 1992 Moratorium document was restricted to certification of Resource Conservation and Recovery Act (RCRA), State and Toxic Substances Control Act (TSCA) hazardous waste from Radioactive Material Management Areas (RMMA). This still remains the primary focus of the Moratorium; however, this document increases the scope to allow use of this methodology to certify other LLNL wastes and materials destined for off-site disposal, transfer, and re-use including non-hazardous wastes and wastes generated outside of RMMAs with the potential for DOE added radioactivity. The LLNL organization that authorizes off-site transfer/disposal of a material or waste stream is responsible for implementing the requirements of this document. The LLNL Radioactive and

Double-walled control valves for the transport of liquids presenting a water pollution hazard; Doppelwandige Stellventile fuer den Transport wassergefaehrdender Fluessigkeiten

Energy Technology Data Exchange (ETDEWEB)

Daume, A.; Weissberg, S. [Daume Regelarmaturen GmbH, Isernhagen (Germany)

2004-09-01

Under German law valves, vessels and connecting pipework containing and/or transporting hazardous substances must be fitted with watertight drip pans or moniterable double walls. This article describes double-walled control valves which are very well suited to meet plant operators' safety requirements and environmental protection requirements. In addition to environmental protection, the valves provide opportunities for cost savings. (orig.)

Working towards a clearer and more helpful hazard map: investigating the influence of hazard map design on hazard communication

Science.gov (United States)

Thompson, M. A.; Lindsay, J. M.; Gaillard, J.

2015-12-01

Globally, geological hazards are communicated using maps. In traditional hazard mapping practice, scientists analyse data about a hazard, and then display the results on a map for stakeholder and public use. However, this one-way, top-down approach to hazard communication is not necessarily effective or reliable. The messages which people take away will be dependent on the way in which they read, interpret, and understand the map, a facet of hazard communication which has been relatively unexplored. Decades of cartographic studies suggest that variables in the visual representation of data on maps, such as colour and symbology, can have a powerful effect on how people understand map content. In practice, however, there is little guidance or consistency in how hazard information is expressed and represented on maps. Accordingly, decisions are often made based on subjective preference, rather than research-backed principles. Here we present the results of a study in which we explore how hazard map design features can influence hazard map interpretation, and we propose a number of considerations for hazard map design. A series of hazard maps were generated, with each one showing the same probabilistic volcanic ashfall dataset, but using different verbal and visual variables (e.g., different colour schemes, data classifications, probabilistic formats). Following a short pilot study, these maps were used in an online survey of 110 stakeholders and scientists in New Zealand. Participants answered 30 open-ended and multiple choice questions about ashfall hazard based on the different maps. Results suggest that hazard map design can have a significant influence on the messages readers take away. For example, diverging colour schemes were associated with concepts of "risk" and decision-making more than sequential schemes, and participants made more precise estimates of hazard with isarithmic data classifications compared to binned or gradational shading. Based on such

EFSA Panels on Biological Hazards (BIOHAZ), on Contaminants in the Food Chain (CONTAM), and on Animal Health and Welfare (AHAW); Scientific Opinion on the public health hazards to be covered by inspection of meat (swine)

DEFF Research Database (Denmark)

Hald, Tine

2011-01-01

A qualitative risk assessment identified Salmonella spp., Yersinia enterocolitica, Toxoplasma gondii and Trichinella spp. as the most relevant biological hazards in the context of meat inspection of swine. A comprehensive pork carcass safety assurance is the only way to ensure their effective...... treatments if necessary. At farm level, risk reduction measures are based on herd health programmes, closed breeding pyramids and GHP/GFP. Chemical substances listed in Council Directive 96/23/EC were ranked into four categories. Dioxins, dioxin-like polychlorinated biphenyls and chloramphenicol were ranked...

An open framework for automated chemical hazard assessment based on GreenScreen for Safer Chemicals: A proof of concept.

Science.gov (United States)

Wehage, Kristopher; Chenhansa, Panan; Schoenung, Julie M

2017-01-01

GreenScreen® for Safer Chemicals is a framework for comparative chemical hazard assessment. It is the first transparent, open and publicly accessible framework of its kind, allowing manufacturers and governmental agencies to make informed decisions about the chemicals and substances used in consumer products and buildings. In the GreenScreen® benchmarking process, chemical hazards are assessed and classified based on 18 hazard endpoints from up to 30 different sources. The result is a simple numerical benchmark score and accompanying assessment report that allows users to flag chemicals of concern and identify safer alternatives. Although the screening process is straightforward, aggregating and sorting hazard data is tedious, time-consuming, and prone to human error. In light of these challenges, the present work demonstrates the usage of automation to cull chemical hazard data from publicly available internet resources, assign metadata, and perform a GreenScreen® hazard assessment using the GreenScreen® "List Translator." The automated technique, written as a module in the Python programming language, generates GreenScreen® List Translation data for over 3000 chemicals in approximately 30 s. Discussion of the potential benefits and limitations of automated techniques is provided. By embedding the library into a web-based graphical user interface, the extensibility of the library is demonstrated. The accompanying source code is made available to the hazard assessment community. Integr Environ Assess Manag 2017;13:167-176. © 2016 SETAC. © 2016 SETAC.

Hazard Analysis Database Report

Energy Technology Data Exchange (ETDEWEB)

GAULT, G.W.

1999-10-13

The Hazard Analysis Database was developed in conjunction with the hazard analysis activities conducted in accordance with DOE-STD-3009-94, Preparation Guide for US Department of Energy Nonreactor Nuclear Facility Safety Analysis Reports, for the Tank Waste Remediation System (TWRS) Final Safety Analysis Report (FSAR). The FSAR is part of the approved TWRS Authorization Basis (AB). This document describes, identifies, and defines the contents and structure of the TWRS FSAR Hazard Analysis Database and documents the configuration control changes made to the database. The TWRS Hazard Analysis Database contains the collection of information generated during the initial hazard evaluations and the subsequent hazard and accident analysis activities. The database supports the preparation of Chapters 3,4, and 5 of the TWRS FSAR and the USQ process and consists of two major, interrelated data sets: (1) Hazard Evaluation Database--Data from the results of the hazard evaluations; and (2) Hazard Topography Database--Data from the system familiarization and hazard identification.

21 CFR 172.510 - Natural flavoring substances and natural substances used in conjunction with flavors.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Natural flavoring substances and natural substances used in conjunction with flavors. 172.510 Section 172.510 Food and Drugs FOOD AND DRUG ADMINISTRATION....510 Natural flavoring substances and natural substances used in conjunction with flavors. Natural...

Priority substances in combined sewer overflows: case study of the Paris sewer network.

Science.gov (United States)

Gasperi, J; Garnaud, S; Rocher, V; Moilleron, R

2011-01-01

This study was undertaken to supply data on both priority pollutant (PP) occurrence and concentrations in combined sewer overflows (CSOs). A single rain event was studied on 13 sites within the Paris sewer network. For each sample, a total of 66 substances, including metals, polycyclic aromatic hydrocarbons (PAHs), pesticides, organotins, volatile organic compounds, chlorobenzenes, phthalates and alkylphenols were analyzed. Of the 66 compounds analyzed in all, 40 PPs including 12 priority hazardous substances were detected in CSOs. As expected, most metals were present in all samples, reflecting their ubiquitous nature. Chlorobenzenes and most pesticides were never quantified above the limit of quantification, while the majority of the other organic pollutants, except DEHP (median concentration: 22 μg.l(-1)), were found to lie in the μg.l(-1) range. For the particular rain event studied, the pollutant loads discharged by CSOs were evaluated and then compared to pollutant loads conveyed by the Seine River. Under the hydraulic conditions considered and according to the estimations performed, this comparison suggests that CSOs are potentially significant local source of metals, PAHs and DEHP. Depending on the substance, the ratio between the CSO and Seine River loads varied from 0.5 to 26, underscoring the important local impact of CSOs at the scale of this storm for most pollutants.

Handbook of hazardous waste management

International Nuclear Information System (INIS)

Metry, A.A.

1980-01-01

The contents of this work are arranged so as to give the reader a detailed understanding of the elements of hazardous waste management. Generalized management concepts are covered in Chapters 1 through 5 which are entitled: Introduction, Regulations Affecting Hazardous Waste Management, Comprehensive Hazardous Waste Management, Control of Hazardous Waste Transportation, and Emergency Hazardous Waste Management. Chapters 6 through 11 deal with treatment concepts and are entitled: General Considerations for Hazardous Waste Management Facilities, Physical Treatment of Hazardous Wastes, Chemical Treatment of Hazardous Wastes, Biological Treatment of Hazardous Wastes, Incineration of Hazardous Wastes, and Hazardous Waste Management of Selected Industries. Chapters 12 through 15 are devoted to ultimate disposal concepts and are entitled: Land Disposal Facilities, Ocean Dumping of Hazardous Wastes, Disposal of Extremely Hazardous Wastes, and Generalized Criteria for Hazardous Waste Management Facilities

Psychotoxic Substances

Science.gov (United States)

1964-11-16

halluci- nations , disturbances of body perception, depersonalization symptoms, and a "psychotic" status. Also with the derivatives, the individual...the substance had also local anesthetic properties. After clinical testing, ibogaine was then used as stimulans for neurasthenics and convalescents1 1 3...con- siderably disturbed by this group of substances. The optic halluci- nations consist to a small extent in scenic proceedings of actions, more

Emerging concepts and requirements for the long-term management of non-radioactive hazardous wastes - would geological disposal be an appropriate solution for some of these wastes

International Nuclear Information System (INIS)

Rein, K. von

1994-01-01

This work deals with the emerging concepts and requirements for the long-term management of non-radioactive hazardous wastes. After some generalities on the pollution of natural environment and the legislations taken by the swedish government the author tries to answer to the question : would geological disposal be an appropriate solution for the non-radioactive hazardous wastes? Then is given the general discussion of the last three articles concerning the background to current environmental policies and their implementation and more particularly the evolution and current thoughts about environmental policies, the managing hazardous activities and substances and the emerging concepts and requirements for the long-term management of non-radioactive hazardous wastes. Comments and questions concerning the similarity or otherwise between the present position of radioactive waste disposal and the background to current environmental policies are indicated. (O.L.)

Predictors of Hazardous Alcohol Consumption Among Young Adult Amphetamine-Type Stimulant Users

Directory of Open Access Journals (Sweden)

Ellen M. Leslie

2016-02-01

Full Text Available Background: Very high levels of alcohol consumption have been observed in young adult amphetamine-type stimulant (i.e., ecstasy and methamphetamine users. The reasons for this association are poorly understood. Objective: To examine predictors of hazardous alcohol consumption in a sample of young adult amphetamine-type stimulant users after 30 months of follow-up, controlling for potential confounders. Method: Analysis of longitudinal data from a population-derived sample of Australian young adult amphetamine-type stimulant users (n = 292. A prediction model of alcohol use at 30 months was developed using generalized linear latent and mixed modeling (GLLAMM. Results: Concurrently using ecstasy (Adjusted Odds Ratio [AOR] = 2.67, 95% Confidence Interval [CI] = [1.41, 5.07], frequently attending nightclubs (AOR = 2.53, 95% CI = [1.04, 6.16], high baseline alcohol use patterns (AOR = 2.06, 95% CI = [1.32, 3.20], and being male (AOR = 3.60, 95% CI = [1.48, 8.78] were associated with an increased likelihood of hazardous alcohol use at 30 months. Conclusion: Concurrent, but not baseline, ecstasy use was associated with hazardous alcohol use, suggesting that combined use of these substances may have an instrumental role in terms of the social functions of drug use (e.g., increasing capacity to drink. Integration of educational interventions concerning alcohol and stimulants is warranted.

Controlled air incineration of hazardous chemical and mixed waste at Los Alamos

International Nuclear Information System (INIS)

Borduin, L.C.; Hutchins, D.A.; Vavruska, J.J.; Warner, C.L.

1987-01-01

The Los Alamos National Laboratory (LANL) Controlled Air Incineration (CAI) system, originally developed for transuranic (TRU) waste volume reduction studies, is currently being qualified for hazardous chemical and mixed waste treatment under provisions of the Resource Conservation and Recovery Act (RCRA). The objective is to obtain a permanent RCRA Part B permit for thermal disposal of hazardous and mixed wastes generated by LANL. Constructed in the mid-1970s as a demonstration project for incineration of TRU solid wastes, the CAI process was substantially modified and tested in 1980-1983 for acceptance of both liquid and solid hazardous chemicals. Successful demonstration of TRU solid waste processing objectives in 1979 and later chemical waste incineration studies have been documented in several publications. In 1984, the LANL CAI became the first US Dept. of Energy (DOE) incinerator to be permitted for polychlorinated biphenyl disposal under the Toxic Substances Control Act. Following establishment of Environmental Protection Agency (EPA) jurisdiction over DOE chemical waste management in 1984, LANL sought and was granted interim status for the CAI and applied for a trial burn permit in the overall laboratory RCRA Part B application. A trial burn and final report have been completed; results have been submitted to EPA and the New Mexico Environmental Improvement Division. This paper provides an overview of trial burn planning and results together with the operational status of LANL's CAI

Australian athletes' knowledge of the WADA Prohibited Substances List and performance enhancing substances.

Science.gov (United States)

Orr, Rhonda; Grassmayr, Matthew; Macniven, Rona; Grunseit, Anne; Halaki, Mark; Bauman, Adrian

2018-03-15

This study investigated athlete knowledge of the World Anti-doping Agency (WADA) Prohibited Substances List and the effects of four well-known performance enhancing substances (PES). A sample of 1925 elite and sub-elite athletes (mean age 20.6 years) completed a questionnaire about the banned status of 30 substances/methods and their knowledge of the effects of amphetamines, anabolic steroids, growth hormone and erythropoietin. Athletes showed limited understanding of the WADA Prohibited Substances List, scoring 32.2% correct, 36.3% incorrect, and 31.4% indicated they did not know the status of 30 substances. Responses of >50% correct were given for only eight substances/method: anabolic steroids, amphetamines, blood doping, erythropoietin, caffeine, vitamins/minerals, protein powders and iron. Athletes demonstrated moderate knowledge of the desired effects of the four PES (49% correct), but poor knowledge of their adverse effects (29% correct). Age, sex, ethnicity, professional/amateur status, and current competition level were significant predictors of the number of correct responses (r 2  = 0.16, p wide range of substances and PES. Better targeted drug education towards younger and non-professional athletes and evaluation of current anti-doping programs are warranted. Copyright © 2018 Elsevier B.V. All rights reserved.

Substance Use Stigma: Reliability and validity of a theory-based scale for substance-using populations*

Science.gov (United States)

Smith, Laramie R.; Earnshaw, Valerie A.; Copenhaver, Michael M.; Cunningham, Chinazo O.

2016-01-01

Background Substance use disorders consistently rank among the most stigmatized conditions worldwide. Thus, substance use stigma fosters health inequities among persons with substance use disorders and remains a key barrier to successful screening and treatment efforts. Current efforts to measure substance use stigma are limited. This study aims to advance measurement efforts by drawing on stigma theory to develop and evaluate the Substance Use Stigma Mechanisms Scale (SU-SMS). The SU-SMS was designed to capture enacted, anticipated, and internalized substance use stigma mechanisms among persons with current and past substance use disorders, and distinguish between key stigma sources most likely to impact this target population. Methods This study was a cross-sectional evaluation of the validity, reliability, and generalizability of the SU-SMS across two independent samples with diverse substance use and treatment histories. Results Findings support the structural and construct validity of the SU-SMS, suggesting the scale was able to capture enacted, anticipated, and internalized stigma as distinct stigma experiences. It also further differentiated between two distinct stigma sources (family and healthcare providers). Analysis of these mechanisms and psychosocial metrics suggests that the scale is also associated with other health-related outcomes. Furthermore, the SU-SMS demonstrated high levels of internal reliability and generalizability across two independent samples of persons with diverse substance use disorders and treatment histories. Conclusion The SU-SMS may serve as a valuable tool for better understanding the processes through which substance use stigma serves to undermine key health behaviors and outcomes among persons with substance use disorders. PMID:26972790

Hazard classification methodology

International Nuclear Information System (INIS)

Brereton, S.J.

1996-01-01

This document outlines the hazard classification methodology used to determine the hazard classification of the NIF LTAB, OAB, and the support facilities on the basis of radionuclides and chemicals. The hazard classification determines the safety analysis requirements for a facility

Hazardous-materials waste disposal: Land, January 1988-July 1991 (Citations from the NTIS Data Base). Rept. for Jan 88-Jul 91

International Nuclear Information System (INIS)

1991-06-01

The bibliography contains citations concerning the disposal of hazardous industrial and municipal wastes, chemical agents, and a variety of other dangerous substances into and from the land. Topics include restoration operations, contamination abatement studies, appropriate regulation and legislation, and remedial response strategies. Considerable attention is given to waste disposal sites at military installations and to incineration operations. Citations pertaining specifically to radioactive waste disposal, state by state toxic release inventories, Best Demonstrated Available Technology as defined by Environmental Protection Agency, Health Assessments for individual companies sponsored by the Toxic Substances and Disease Registry, Atlanta, GA., and the Superfund Record of Decisions are excluded. (The bibliography contains 153 citations with a subject index.)

Hazardous materials waste disposal: Water, January 1988-July 1991 (Citations from the NTIS Data Base). Rept. for Jan 88-Jul 91

International Nuclear Information System (INIS)

1991-06-01

The bibliography contains citations concerning the disposal of hazardous industrial and municipal wastes, chemical agents, and a variety of other dangerous substances into and from the water. Topics include restoration operations, contamination abatement studies, appropriate regulation and legislation, and remedial response strategies. Considerable attention is given to waste disposal sites at military installations and to incineration operations. Citations pertaining specifically to radioactive waste disposal, state by state toxic release inventories, Best Demonstrated Available Technology as defined by Environmental Protection Agency, Health Assessments for individual companies sponsored by the Toxic Substances and Disease Registry, Atlanta, GA., and the Superfund Record of Decisions are excluded. (The bibliography contains 153 citations with a subject index.)

Biogeosystem technique as a method to overcome the Biological and Environmental Hazards of modern Agricultural, Irrigational and Technological Activities

Science.gov (United States)

Kalinitchenko, Valery; Batukaev, Abdulmalik; Zinchenko, Vladimir; Zarmaev, Ali; Magomadov, Ali; Chernenko, Vladimir; Startsev, Viktor; Bakoev, Serojdin; Dikaev, Zaurbek

2014-05-01

Modern challenge for humanity is to replace the paradigm of nature use and overcome environmental hazards of agronomy, irrigation, industry, and other human activities in biosphere. It is utterly reasonable to stop dividing biosphere on shares - the human habitat and the environment. In the 21st century it is an outdated anthropocentrism. Contradicting himself to biosphere Humankind has the problems. The new paradigm of biosphere control by methods of Biogeosystem technique is on agenda of Humankind. Key directions of Biogeosystem technique. Tillage. Single rotary milling 20…30-50…60 sm soil layer optimizes the evolution and environment of soil, creates a favorable conditions for the rhizosphere, increases the biological productivity of biosphere by 30-50% compared to the standard agricultural practices for the period up to 40 years. Recycle material. Recycling of mineral and organic substances in soil layer of 20…30-50…60 sm in rotary milling soil processing provides wastes clean return to biosphere. Direct intrasoil substances synthesis. Environmentally friendly robot wasteless nanotechnology provides direct substances synthesis, including fertilizers, inside the soil. It eliminates the prerequisites of the wastes formation under standard industrial technologies. Selective substance's extraction from soil. Electrochemical robotic nanotechnology provides selective substances extraction from soil. The technology provides recovery, collection and subsequent safe industrial use of extracted substances out of landscape. Saving fresh water. An important task is to save fresh water in biosphere. Irrigation spends water 4-5 times more of biological requirements of plants, leads to degradation of soil and landscape. The intrasoil pulse continuous-discrete paradigm of irrigation is proposed. It provides the soil and landscape conservation, increases the biological productivity, save the fresh water up to 10-20 times. The subsurface soil rotary processing and

Combination of material flow analysis and substance flow analysis: a powerful approach for decision support in waste management.

Science.gov (United States)

Stanisavljevic, Nemanja; Brunner, Paul H

2014-08-01

The novelty of this paper is the demonstration of the effectiveness of combining material flow analysis (MFA) with substance flow analysis (SFA) for decision making in waste management. Both MFA and SFA are based on the mass balance principle. While MFA alone has been applied often for analysing material flows quantitatively and hence to determine the capacities of waste treatment processes, SFA is more demanding but instrumental in evaluating the performance of a waste management system regarding the goals "resource conservation" and "environmental protection". SFA focuses on the transformations of wastes during waste treatment: valuable as well as hazardous substances and their transformations are followed through the entire waste management system. A substance-based approach is required because the economic and environmental properties of the products of waste management - recycling goods, residues and emissions - are primarily determined by the content of specific precious or harmful substances. To support the case that MFA and SFA should be combined, a case study of waste management scenarios is presented. For three scenarios, total material flows are quantified by MFA, and the mass flows of six indicator substances (C, N, Cl, Cd, Pb, Hg) are determined by SFA. The combined results are compared to the status quo in view of fulfilling the goals of waste management. They clearly point out specific differences between the chosen scenarios, demonstrating potentials for improvement and the value of the combination of MFA/SFA for decision making in waste management. © The Author(s) 2014.

Impulsive lifestyle counseling to prevent dropout from treatment for substance use disorders in people with antisocial personality disorder: A randomized study.

Science.gov (United States)

Thylstrup, Birgitte; Hesse, Morten

2016-06-01

Patients with antisocial personality disorder in outpatient treatment for substance use disorders are at high risk of drop-out. Using a randomized design, this study tested the impact of adding a brief psycho-educational program, the Impulsive Lifestyle Counseling program, to outpatient substance abuse treatment in order to prevent treatment dropout. Patients (N=175) were recruited from 13 municipal treatment centers in Denmark, and assigned to treatment as usual or to the experimental condition. In all, 172 patients could be included in the analyses. In the intent-to-treat analysis, the risk of treatment dropout was reduced among patients randomized to the experimental program (hazard ratio=0.63, p=.031), after controlling for age, gender, and substitution treatment status. The study supported the efficacy of the Impulsive Lifestyle Counseling program as a method for preventing treatment dropout for patients with comorbid antisocial personality disorder in substance abuse treatment. Trial registration #ISRCTN67266318. Copyright © 2016 Elsevier Ltd. All rights reserved.

Potential environmental impacts of light-emitting diodes (LEDs): metallic resources, toxicity, and hazardous waste classification.

Science.gov (United States)

Lim, Seong-Rin; Kang, Daniel; Ogunseitan, Oladele A; Schoenung, Julie M

2011-01-01

Light-emitting diodes (LEDs) are advertised as environmentally friendly because they are energy efficient and mercury-free. This study aimed to determine if LEDs engender other forms of environmental and human health impacts, and to characterize variation across different LEDs based on color and intensity. The objectives are as follows: (i) to use standardized leachability tests to examine whether LEDs are to be categorized as hazardous waste under existing United States federal and California state regulations; and (ii) to use material life cycle impact and hazard assessment methods to evaluate resource depletion and toxicity potentials of LEDs based on their metallic constituents. According to federal standards, LEDs are not hazardous except for low-intensity red LEDs, which leached Pb at levels exceeding regulatory limits (186 mg/L; regulatory limit: 5). However, according to California regulations, excessive levels of copper (up to 3892 mg/kg; limit: 2500), Pb (up to 8103 mg/kg; limit: 1000), nickel (up to 4797 mg/kg; limit: 2000), or silver (up to 721 mg/kg; limit: 500) render all except low-intensity yellow LEDs hazardous. The environmental burden associated with resource depletion potentials derives primarily from gold and silver, whereas the burden from toxicity potentials is associated primarily with arsenic, copper, nickel, lead, iron, and silver. Establishing benchmark levels of these substances can help manufacturers implement design for environment through informed materials substitution, can motivate recyclers and waste management teams to recognize resource value and occupational hazards, and can inform policymakers who establish waste management policies for LEDs.

40 CFR 373.4 - Definitions.

Science.gov (United States)

2010-07-01

... COMMUNITY RIGHT-TO-KNOW PROGRAMS REPORTING HAZARDOUS SUBSTANCE ACTIVITY WHEN SELLING OR TRANSFERRING FEDERAL... definitions apply: (a) Hazardous substances means that group of substances defined as hazardous under CERCLA 101(14), and that appear at 40 CFR 302.4. (b) Storage means the holding of hazardous substances for a...

Urgent need to reevaluate the latest World Health Organization guidelines for toxic inorganic substances in drinking water.

Science.gov (United States)

Frisbie, Seth H; Mitchell, Erika J; Sarkar, Bibudhendra

2015-08-13

The World Health Organization (WHO) has established guidelines for drinking-water quality that cover biological and chemical hazards from both natural and anthropogenic sources. In the most recent edition of Guidelines for Drinking-water Quality (2011), the WHO withdrew, suspended, did not establish, or raised guidelines for the inorganic toxic substances manganese, molybdenum, nitrite, aluminum, boron, nickel, uranium, mercury, and selenium. In this paper, we review these changes to the WHO drinking-water guidelines, examining in detail the material presented in the WHO background documents for each of these toxic substances. In some cases, these WHO background documents use literature reviews that do not take into account scientific research published within the last 10 or more years. In addition, there are instances in which standard WHO practices for deriving guidelines are not used; for example, rounding and other mathematical errors are made. According to published meeting reports from the WHO Chemical Aspects Working Group, the WHO has a timetable for revising some of its guidelines for drinking-water quality, but for many of these toxic substances the planned changes are minimal or will be delayed for as long as 5 years. Given the limited nature of the planned WHO revisions to the inorganic toxic substances and the extended timetable for these revisions, we suggest that governments, researchers, and other stakeholders might establish independent recommendations for inorganic toxic substances and possibly other chemicals to proactively protect public health, or at the very least, revert to previous editions of the Guidelines for Drinking-water Quality, which were more protective of public health.

Perfluoroalkyl substances during pregnancy and validated preeclampsia among nulliparous women in the Norwegian Mother and Child Cohort Study.

Science.gov (United States)

Starling, Anne P; Engel, Stephanie M; Richardson, David B; Baird, Donna D; Haug, Line S; Stuebe, Alison M; Klungsøyr, Kari; Harmon, Quaker; Becher, Georg; Thomsen, Cathrine; Sabaredzovic, Azemira; Eggesbø, Merete; Hoppin, Jane A; Travlos, Gregory S; Wilson, Ralph E; Trogstad, Lill I; Magnus, Per; Longnecker, Matthew P

2014-04-01

Perfluoroalkyl substances (PFAS) are persistent and ubiquitous environmental contaminants, and human exposure to these substances may be related to preeclampsia, a common pregnancy complication. Previous studies have found serum concentrations of PFAS to be positively associated with pregnancy-induced hypertension and preeclampsia in a population with high levels of exposure to perfluorooctanoate. Whether this association exists among pregnant women with background levels of PFAS exposure is unknown. Using data from the Norwegian Mother and Child Cohort Study conducted by the Norwegian Institute of Public Health, we carried out a study of nulliparous pregnant women enrolled in 2003-2007 (466 cases, 510 noncases) to estimate associations between PFAS concentrations and an independently validated diagnosis of preeclampsia. We measured levels of 9 PFAS in maternal plasma extracted midpregnancy; statistical analyses were restricted to 7 PFAS that were quantifiable in more than 50% of samples. In proportional hazards models adjusted for maternal age, prepregnancy body mass index (weight (kg)/height (m)(2)), educational level, and smoking status, we observed no strongly positive associations between PFAS levels and preeclampsia. We found an inverse association between preeclampsia and the highest quartile of perfluoroundecanoic acid concentration relative to the lowest quartile (hazard ratio = 0.55, 95% confidence interval: 0.38, 0.81). Overall, our findings do not support an increased risk of preeclampsia among nulliparous Norwegian women with background levels of PFAS exposure.

Definition of Time Induction of Self-Ignition of the Substance on the Prognostic Extrapolation Depending on the Basis of Indicators Fire and Explosion Hazard

International Nuclear Information System (INIS)

Sechin, A; Kyrmakova, O; Osipenko, S

2016-01-01

In this article the research directed on development of a technique of definition of time of induction of the self-ignition of substances and materials which is an indicator of the beginning of development of an emergency is conducted. The experiment consisting in supervision over process of self-ignition of coal and oil deposits was the basis for research. On the basis of experimental data the curve expressing analytic - expected dependence of size of temperature of ignition on induction time was constructed. Proceeding from graphical representation of process, functional dependence of time of induction on a temperature indicator was received: y = 16920 • x 0 537 . By means of known indicators of such substances as bitumen oil oxidized (the combustible solid substance received by oxidation of residual product of oil refining) and tar oil (the combustible solid substance which is residual product of oil refining) and the received algorithm, verification of reliability of the received dependence and a technique of definition of time of induction of spontaneous ignition of deposits of oil in general was carried out. The practical importance of the conducted research is that having data on time of induction of process of self-ignition, by means of preventive measures becomes possible to avoid and prevent accidents in oil and oil processing branches, at the same time loss of property and loss of human life. (paper)

Psychopathology in Substance Use Disorder Patients with and without Substance-Induced Psychosis

Directory of Open Access Journals (Sweden)

Simon Zhornitsky

2015-01-01

Full Text Available Background. Substance-induced psychotic disorder (SIPD is a diagnosis constructed to distinguish substance-induced psychotic states from primary psychotic disorders. A number of studies have compared SIPD persons with primary psychotic patients, but there is little data on what differentiates substance use disorder (SUD individuals with and without SIPD. Here, we compared psychopathology, sociodemographic variables, and substance use characteristics between SUD patients with and without SIPD. Methods. A retrospective chart review was conducted on newly admitted patients at a rehabilitation centre between 2007 and 2012. Results. Of the 379 patients included in the study, 5% were diagnosed with SIPD n=19 and 95% were diagnosed with SUDs without SIPD n=360. More SIPD patients reported using cannabis and psychostimulants, and fewer SIPD patients reported using alcohol than SUDs patients without SIPD. SIPD patients scored higher on the “schizophrenia nuclear symptoms” dimension of the SCL-90R psychoticism scale and exhibited more ClusterB personality traits than SUD patients without SIPD. Discussion. These data are consistent with previous studies suggesting that psychopathology, substance type, and sociodemographic variables play important role in the development of SIPD. More importantly, the results highlight the need for paying greater attention to the types of self-reported psychotic symptoms during the assessment of psychotomimetic effects associated with psychoactive substances.

Treatment of Concurrent Substance Dependence, Child Neglect and Domestic Violence: A Single Case Examination Involving Family Behavior Therapy

Science.gov (United States)

Romero, Valerie; Allen, Daniel N.

2012-01-01

Although child neglect and substance abuse co-occur in greater than 60% of child protective service cases, intervention outcome studies are deplorably lacking. Therefore, a home-based Family Behavior Therapy is described in the treatment of a woman evidencing child neglect, substance dependence, domestic violence and other co-occurring problems. Treatment included contingency management, self control, stimulus control, communication and child management skills training exercises, and financial management components. Results indicated improvements in child abuse potential, home hazards, domestic violence, and drug use, which were substantiated by objective urinalysis testing, and tours of her home. Validity checks indicated the participant was being truthful in her responses to standardized questionnaires, and assessors were “blind” to study intent. Limitations (i.e., lack of experimental control and follow-up data collection) of this case example are discussed in light of these results. PMID:23226920

Hazard Analysis Database Report

CERN Document Server

Grams, W H

2000-01-01

The Hazard Analysis Database was developed in conjunction with the hazard analysis activities conducted in accordance with DOE-STD-3009-94, Preparation Guide for U S . Department of Energy Nonreactor Nuclear Facility Safety Analysis Reports, for HNF-SD-WM-SAR-067, Tank Farms Final Safety Analysis Report (FSAR). The FSAR is part of the approved Authorization Basis (AB) for the River Protection Project (RPP). This document describes, identifies, and defines the contents and structure of the Tank Farms FSAR Hazard Analysis Database and documents the configuration control changes made to the database. The Hazard Analysis Database contains the collection of information generated during the initial hazard evaluations and the subsequent hazard and accident analysis activities. The Hazard Analysis Database supports the preparation of Chapters 3 ,4 , and 5 of the Tank Farms FSAR and the Unreviewed Safety Question (USQ) process and consists of two major, interrelated data sets: (1) Hazard Analysis Database: Data from t...

Hospital Admission and Criminality Associated with Substance Misuse in Young Refugees - A Swedish National Cohort Study.

Science.gov (United States)

Manhica, Hélio; Gauffin, Karl; Almqvist, Ylva B; Rostila, Mikael; Hjern, Anders

2016-01-01

High rates of mental health problems have been described in young refugees, but few studies have been conducted on substance misuse. This study aimed to investigate the patterns of hospital care and criminality associated with substance misuse in refugees who settled in Sweden as teenagers. Gender stratified Cox regression models were used to estimate the risks of criminal convictions and hospital care associated with substance misuse from national Swedish data for 2005-2012. We focused on 22,992 accompanied and 5,686 unaccompanied refugees who were aged 13-19 years when they settled in Sweden and compared them with 1 million native Swedish youths from the same birth cohort. The risks of criminal conviction associated with substance misuse increased with the length of residency in male refugees, after adjustment for age and domicile. The hazard ratios (HRs) were 5.21 (4.39-6.19) for unaccompanied and 3.85 (3.42-4.18) for accompanied refugees after more than 10 years of residency, compared with the native population. The risks were slightly lower for hospital care, at 2.88 (2.18-3.79) and 2.52(2.01-3.01) respectively. Risks were particularly pronounced for male refugees from the Horn of Africa and Iran. The risks for all male refugees decreased substantially when income was adjusted for. Young female refugees had similar risks to the general population. The risks of criminality and hospital care associated with substance misuse in young male refugees increased with time of residency in Sweden and were associated with a low level of income compared with the native Swedish population. Risks were similar in accompanied and unaccompanied refugees.

The Matthew effect in environmental science publication: a bibliometric analysis of chemical substances in journal articles.

Science.gov (United States)

Grandjean, Philippe; Eriksen, Mette L; Ellegaard, Ole; Wallin, Johan A

2011-11-10

While environmental research addresses scientific questions of possible societal relevance, it is unclear to what degree research focuses on environmental chemicals in need of documentation for risk assessment purposes. In a bibliometric analysis, we used SciFinder to extract Chemical Abstract Service (CAS) numbers for chemicals addressed by publications in the 78 major environmental science journals during 2000-2009. The Web of Science was used to conduct title searches to determine long-term trends for prominent substances and substances considered in need of research attention. The 119,636 journal articles found had 760,056 CAS number links during 2000-2009. The top-20 environmental chemicals consisted of metals, (chlorinated) biphenyls, polyaromatic hydrocarbons, benzene, and ethanol and contributed 12% toward the total number of links- Each of the top-20 substances was covered by 2,000-10,000 articles during the decade. The numbers for the 10-year period were similar to the total numbers of pre-2000 articles on the same chemicals. However, substances considered a high priority from a regulatory viewpoint, due to lack of documentation, showed very low publication rates. The persistence in the scientific literature of the top-20 chemicals was only weakly related to their publication in journals with a high impact factor, but some substances achieved high citation rates. The persistence of some environmental chemicals in the scientific literature may be due to a 'Matthew' principle of maintaining prominence for the very reason of having been well researched. Such bias detracts from the societal needs for documentation on less well known environmental hazards, and it may also impact negatively on the potentials for innovation and discovery in research.

Toxic substances alert program

Science.gov (United States)

Junod, T. L.

1978-01-01

A toxicity profile is provided, of 187 toxic substances procured by NASA Lewis Research Center during a 3 1/2 year period, including 27 known or suspected carcinogens. The goal of the program is to assure that the center's health and safety personnel are aware of the procurement and use of toxic substances and to alert and inform the users of these materials as to the toxic characteristics and the control measures needed to ensure their safe use. The program also provides a continuing record of the toxic substances procured, who procured them, what other toxic substances the user has obtained in the past, and where similar materials have been used elsewhere at the center.

Perfluoroalkyl and polyfluoroalkyl substances in sediments from South Bohai coastal watersheds, China

International Nuclear Information System (INIS)

Zhu, Zhaoyun; Wang, Tieyu; Wang, Pei; Lu, Yonglong; Giesy, John P.

2014-01-01

Highlights: • Relatively high concentrations of PFAS, especially PFOA, were found in the Xiaoqing River sediment. • PFOA and PFBS were the dominant PFAS in the sediments from coastal and riverine area, respectively. • Concentrations of PFNA, PFDA and PFHxS in sediment were significantly correlated with concentrations of organic carbon. • Risks posed by PFOA and PFOS to benthic organisms from concentrations of PFAS in sediments were small. - Abstract: This study investigated the concentrations and distribution of Perfluoroalkyl and polyfluoroalkyl substances (PFAS) in sediments of 12 rivers from South Bohai coastal watersheds. The highest concentrations of ΣPFAS (31.920 ng g −1 dw) and PFOA (29.021 ng g −1 dw) were found in sediments from the Xiaoqing River, which was indicative of local point sources in this region. As for other rivers, concentrations of ΣPFAS ranged from 0.218 to 1.583 ng g −1 dw were found in the coastal sediments and from 0.167 to 1.953 ng g −1 dw in the riverine sediments. Predominant PFAS from coastal and riverine areas were PFOA and PFBS, with percentages of 30% and 35%, respectively. Partitioning analysis showed the concentrations of PFNA, PFDA and PFHxS were significantly correlated with organic carbon. The results of a preliminary environmental hazard assessment showed that PFOS posed the highest hazard in the Mi River, while PFOA posed a relative higher hazard in the Xiaoqing River

ThinkHazard!: an open-source, global tool for understanding hazard information

Science.gov (United States)

Fraser, Stuart; Jongman, Brenden; Simpson, Alanna; Nunez, Ariel; Deparday, Vivien; Saito, Keiko; Murnane, Richard; Balog, Simone

2016-04-01

Rapid and simple access to added-value natural hazard and disaster risk information is a key issue for various stakeholders of the development and disaster risk management (DRM) domains. Accessing available data often requires specialist knowledge of heterogeneous data, which are often highly technical and can be difficult for non-specialists in DRM to find and exploit. Thus, availability, accessibility and processing of these information sources are crucial issues, and an important reason why many development projects suffer significant impacts from natural hazards. The World Bank's Global Facility for Disaster Reduction and Recovery (GFDRR) is currently developing a new open-source tool to address this knowledge gap: ThinkHazard! The main aim of the ThinkHazard! project is to develop an analytical tool dedicated to facilitating improvements in knowledge and understanding of natural hazards among non-specialists in DRM. It also aims at providing users with relevant guidance and information on handling the threats posed by the natural hazards present in a chosen location. Furthermore, all aspects of this tool will be open and transparent, in order to give users enough information to understand its operational principles. In this presentation, we will explain the technical approach behind the tool, which translates state-of-the-art probabilistic natural hazard data into understandable hazard classifications and practical recommendations. We will also demonstrate the functionality of the tool, and discuss limitations from a scientific as well as an operational perspective.

Substance abuse and child maltreatment.

Science.gov (United States)

Wells, Kathryn

2009-04-01

Pediatricians and other medical providers caring for children need to be aware of the dynamics in the significant relationship between substance abuse and child maltreatment. A caregiver's use and abuse of alcohol, marijuana, heroin, cocaine, methamphetamine, and other drugs place the child at risk in multiple ways. Members of the medical community need to understand these risks because the medical community plays a unique and important role in identifying and caring for these children. Substance abuse includes the abuse of legal drugs as well as the use of illegal drugs. The abuse of legal substances may be just as detrimental to parental functioning as abuse of illicit substances. Many substance abusers are also polysubstance users and the compounded effect of the abuse of multiple substances may be difficult to measure. Often other interrelated social features, such as untreated mental illness, trauma history, and domestic violence, affect these families.

Regulations on the supervision and use of installations, apparatus, material and substances which release ionizing or other radiation representing danger to health (23 January 1976)

International Nuclear Information System (INIS)

These Regulations repeal the Regulations of 22 October 1948 on the surveillance of facilities using X-rays and radium. They were issued in the Norwegian Official Gazette, 1st Section of 3 February 1976, and contain instructions on the control and use of facilities, devices, equipment and substances emitting ionizing radiation hazardous to health. This control applies to use for medical, veterinary, scientific, industrial or to ionizing radiation for other purposes as well as to all vessels, waste and discharge of substances emitting ionizing radiation. Finally, the Regulations specify the competent body, the type of devices concerned, and the duties of persons using such devices. (NEA) [fr

When acute-stage psychosis and substance use co-occur: differentiating substance-induced and primary psychotic disorders.

Science.gov (United States)

Caton, C L; Samet, S; Hasin, D S

2000-09-01

Substances such as alcohol, cocaine, amphetamine, and cannabis can produce psychotic reactions in individuals who are otherwise free of serious mental illness. However, persons with primary psychotic disorders, such as schizophrenia and bipolar disorder, who use these substances often present for treatment with signs and symptoms similar to those whose psychosis resulted from the use of drugs alone. While it is often difficult to distinguish substance-induced from primary psychoses, especially early in the course of treatment, this differential diagnosis has important implications for treatment planning. To help clinicians distinguish these two types of presentations, the authors first review the types of psychotic symptoms that can co-occur with substance use. They discuss the prevalence and patterns of substance use that have been found in patients with schizophrenia and other primary psychotic disorders and review the negative outcomes associated with substance use in this population. The prevalence of and types of symptoms and problems associated with psychotic symptoms that occur as a result of substance use alone are also reviewed. The authors describe assessment procedures for differentiating substance-induced and primary psychotic disorders. They stress the importance of accurately establishing the temporal relationship between the substance use and the onset and continuation of psychotic symptoms in making a differential diagnosis, as well as the importance of being familiar with the types of psychological symptoms that can occur with specific substances. The authors review the utility and limitations of a number of diagnostic instruments for assessing patients with co-occurring psychosis and substance use problems, including The Addiction Severity Index, The Michigan Alcohol Screening Test, and diagnostic interviews such as the Schedule for Affective Disorders and Schizophrenia and the Structured Clinical Interview for DSM. They then discuss the

Multi-Hazard Interactions in Guatemala

Science.gov (United States)

Gill, Joel; Malamud, Bruce D.

2017-04-01

In this paper, we combine physical and social science approaches to develop a multi-scale regional framework for natural hazard interactions in Guatemala. The identification and characterisation of natural hazard interactions is an important input for comprehensive multi-hazard approaches to disaster risk reduction at a regional level. We use five transdisciplinary evidence sources to organise and populate our framework: (i) internationally-accessible literature; (ii) civil protection bulletins; (iii) field observations; (iv) stakeholder interviews (hazard and civil protection professionals); and (v) stakeholder workshop results. These five evidence sources are synthesised to determine an appropriate natural hazard classification scheme for Guatemala (6 hazard groups, 19 hazard types, and 37 hazard sub-types). For a national spatial extent (Guatemala), we construct and populate a "21×21" hazard interaction matrix, identifying 49 possible interactions between 21 hazard types. For a sub-national spatial extent (Southern Highlands, Guatemala), we construct and populate a "33×33" hazard interaction matrix, identifying 112 possible interactions between 33 hazard sub-types. Evidence sources are also used to constrain anthropogenic processes that could trigger natural hazards in Guatemala, and characterise possible networks of natural hazard interactions (cascades). The outcomes of this approach are among the most comprehensive interaction frameworks for national and sub-national spatial scales in the published literature. These can be used to support disaster risk reduction and civil protection professionals in better understanding natural hazards and potential disasters at a regional scale.

Properties, performance and associated hazards of state-of-the-art durable water repellent (DWR) chemistry for textile finishing.

Science.gov (United States)

Holmquist, H; Schellenberger, S; van der Veen, I; Peters, G M; Leonards, P E G; Cousins, I T

2016-05-01

Following the phase-out of long-chain per- and polyfluoroalkyl substances (PFASs), the textile industry had to find alternatives for side-chain fluorinated polymer based durable water repellent (DWR) chemistries that incorporated long perfluoroalkyl side chains. This phase-out and subsequent substitution with alternatives has resulted in a market where both fluorinated and non-fluorinated DWRs are available. These DWR alternatives can be divided into four broad groups that reflect their basic chemistry: side-chain fluorinated polymers, silicones, hydrocarbons and other chemistries (includes dendrimer and inorganic nanoparticle chemistries). In this critical review, the alternative DWRs are assessed with regards to their structural properties and connected performance, loss and degradation processes resulting in diffuse environmental emissions, and hazard profiles for selected emitted substances. Our review shows that there are large differences in performance between the alternative DWRs, most importantly the lack of oil repellence of non-fluorinated alternatives. It also shows that for all alternatives, impurities and/or degradation products of the DWR chemistries are diffusively emitted to the environment. Our hazard ranking suggests that hydrocarbon based DWR is the most environmentally benign, followed by silicone and side-chain fluorinated polymer-based DWR chemistries. Industrial commitments to reduce the levels of impurities in silicone based and side-chain fluorinated polymer based DWR formulations will lower the actual risks. There is a lack of information on the hazards associated with DWRs, in particular for the dendrimer and inorganic nanoparticle chemistries, and these data gaps must be filled. Until environmentally safe alternatives, which provide the required performance, are available our recommendation is to choose DWR chemistry on a case-by-case basis, always weighing the benefits connected to increased performance against the risks to the

The results of the toxicity and hazard studies of isopropyl meta-carborane with single administration to laboratory animals

Directory of Open Access Journals (Sweden)

Yushkov G.G.

2018-04-01

Full Text Available Intensive research on the chemistry of borohydrides and the creation of high-energy fuels led to the discovery of a completely new type of organoboron compounds, which were collectively called carboranes. Taking into account the scope of application of organoboron compounds in various branches of human economic activity, we present for publication the quantitative data of a toxicological study of the higher isomer of carboranes of isopropyl meta-carborane at the level of a single injection into the laboratory animals through the mouth and lungs. Background. Supplementing data on toxicity and the hazard of organoboron compounds requires the study of the response of the organism to the action of isopropyl meta-carborane. The purpose of the study: identification of possible features and specificity of the toxic effect of carboranes on the example of isopropyl meta-carborane. Methods. The object of the study is nonlinear laboratory animals: rats, mice and rabbits contained in standard vivarium conditions, with observance of the rules of humane treatment of animals. Traditional methods of research (physiological, hematological, morphological have been used. Statistical processing of data was carried out using the programs «Microsoft Office Excel 2007» and «Biostat». Differences were considered statistically significant at p ≤ 0.05, using a parametric test. Results. Acute toxicity parameters were obtained, which allowed the substance to be classified as moderately hazardous (3rd hazard class according to GOST 12.1.007, which does not have selective irritant, pneumotoxic and fibrogenic effects. Conclusion. Thus, the predominant influence of the substance is established objectively with a single exposure to the blood system as its toxicological feature, and its effect on spermatozoa is a specificity of the action, which stimulates the study of this carborane under conditions of chronic administration to the animals.

Playing video games while using or feeling the effects of substances: associations with substance use problems.

Science.gov (United States)

Ream, Geoffrey L; Elliott, Luther C; Dunlap, Eloise

2011-10-01

This study tested the hypothesis that playing video games while using or feeling the effects of a substance--referred to herein as "concurrent use"-is related to substance use problems after controlling for substance use frequency, video gaming as an enthusiastic hobby, and demographic factors. Data were drawn from a nationally representative online survey of adult video gamers conducted by Knowledge Networks, valid n = 2,885. Problem video game playing behavior was operationalized using Tejeiro Salguero and Bersabé Morán's 2002 problem video game play (PVP) measure, and measures for substance use problems were taken from the National Survey of Drug Use and Health (NSDUH). Separate structural equation modeling analyses were conducted for users of caffeine, tobacco, alcohol, and marijuana. In all four models, concurrent use was directly associated with substance use problems, but not with PVP. Video gaming as an enthusiastic hobby was associated with substance use problems via two indirect paths: through PVP for all substances, and through concurrent use for caffeine, tobacco, and alcohol only. Results illustrate the potential for "drug interaction" between self-reinforcing behaviors and addictive substances, with implications for the development of problem use.

Hazard management at the workplace

International Nuclear Information System (INIS)

Hasfazilah Hassan; Azimawati Ahmad; Syed Asraf Fahlawi Wafa S M Ghazi; Hairul Nizam Idris

2005-01-01

Failure to ensure health and safety environment at workplace will cause an accident involving loss to the time, human resource, finance and for the worse case effect the moral value of an organization. If we go through to the cause of the accident, it is impossible to have a totally safety workplace. It is because every process in work activities has it own hazard elements. The purpose of this paper is to discuss the best action to prevent from the hazard with a comprehensive and effectiveness hazard management. Hazard management is the one of the pro-active hazard control. With this we manage to identify and evaluate the hazard and control the hazard risk. Therefore, hazard management should be screened constantly and continuously to make sure work hazard always in control. (Author)

Emissions of perfluorinated alkylated substances (PFAS) from point sources--identification of relevant branches.

Science.gov (United States)

Clara, M; Scheffknecht, C; Scharf, S; Weiss, S; Gans, O

2008-01-01

Effluents of wastewater treatment plants are relevant point sources for the emission of hazardous xenobiotic substances to the aquatic environment. One group of substances, which recently entered scientific and political discussions, is the group of the perfluorinated alkylated substances (PFAS). The most studied compounds from this group are perfluorooctanoic acid (PFOA) and perfluorooctane sulphonate (PFOS), which are the most important degradation products of PFAS. These two substances are known to be persistent, bioaccumulative and toxic (PBT). In the present study, eleven PFAS were investigated in effluents of municipal wastewater treatment plants (WWTP) and in industrial wastewaters. PFOS and PFOA proved to be the dominant compounds in all sampled wastewaters. Concentrations of up to 340 ng/L of PFOS and up to 220 ng/L of PFOA were observed. Besides these two compounds, perfluorohexanoic acid (PFHxA) was also present in nearly all effluents and maximum concentrations of up to 280 ng/L were measured. Only N-ethylperfluorooctane sulphonamide (N-EtPFOSA) and its degradation/metabolisation product perfluorooctane sulphonamide (PFOSA) were either detected below the limit of quantification or were not even detected at all. Beside the effluents of the municipal WWTPs, nine industrial wastewaters from six different industrial branches were also investigated. Significantly, the highest emissions or PFOS were observed from metal industry whereas paper industry showed the highest PFOA emission. Several PFAS, especially perfluorononanoic acid (PFNA), perfluorodecanoic acid (PFDA), perfluorododecanoic acid (PFDoA) and PFOS are predominantly emitted from industrial sources, with concentrations being a factor of 10 higher than those observed in the municipal WWTP effluents. Perfluorodecane sulphonate (PFDS), N-Et-PFOSA and PFOSA were not detected in any of the sampled industrial point sources. (c) IWA Publishing 2008.

DOE Hazardous Waste Program

International Nuclear Information System (INIS)

Eyman, L.D.; Craig, R.B.

1985-01-01

The goal of the DOE Hazardous Waste Program is to support the implementation and improvement of hazardous-chemical and mixed-radioactive-waste management such that public health, safety, and the environment are protected and DOE missions are effectively accomplished. The strategy for accomplishing this goal is to define the character and magnitude of hazardous wastes emanating from DOE facilities, determine what DOE resources are available to address these problems, define the regulatory and operational constraints, and develop programs and plans to resolve hazardous waste issues. Over the longer term the program will support the adaptation and application of technologies to meet hazardous waste management needs and to implement an integrated, DOE-wide hazardous waste management strategy. 1 reference, 1 figure

Lessons to be learned from radioactive waste disposal practices for non-radioactive hazardous waste management

International Nuclear Information System (INIS)

Merz, E.R.

1991-01-01

The criteria to be set up for any kind of hazardous waste disposal must always be put in perspective: 1. what are the waste characteristics? 2. what time period for safe isolation is of interest? 3. which geological disposal alternatives exist? Different approaches may be used in the short- and long-term perspective. In either case, a general procedure is recommended which involves concentrating, containing and isolating the source of toxicity, both radioactive and chemotoxic substances, as far as practicable. Waste characterization of either chemotoxic or radioactive wastes should be performed applying comparable scientifically based principles. The important question which arises is whether their hazard potential can be quantified on the basis of dose comparison regarding the morbidity effects of radiation and of chemical pollutants. Good control over the consequences of hazardous waste disposal requires threat detailed criteria for tolerable contamination of radioactive as well as chemical pollutants should be established, and that compliance with these criteria can be demonstrated. As yet, there are no well developed principles for assessing the detriment from most types of genotoxic waste other than radioactive material. The time horizon discussed for both categories of waste for their proof of safe isolation differs by a factor of about one hundred. (au)

A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment.

Science.gov (United States)

Scholz, Stefan; Sela, Erika; Blaha, Ludek; Braunbeck, Thomas; Galay-Burgos, Malyka; García-Franco, Mauricio; Guinea, Joaquin; Klüver, Nils; Schirmer, Kristin; Tanneberger, Katrin; Tobor-Kapłon, Marysia; Witters, Hilda; Belanger, Scott; Benfenati, Emilio; Creton, Stuart; Cronin, Mark T D; Eggen, Rik I L; Embry, Michelle; Ekman, Drew; Gourmelon, Anne; Halder, Marlies; Hardy, Barry; Hartung, Thomas; Hubesch, Bruno; Jungmann, Dirk; Lampi, Mark A; Lee, Lucy; Léonard, Marc; Küster, Eberhard; Lillicrap, Adam; Luckenbach, Till; Murk, Albertinka J; Navas, José M; Peijnenburg, Willie; Repetto, Guillermo; Salinas, Edward; Schüürmann, Gerrit; Spielmann, Horst; Tollefsen, Knut Erik; Walter-Rohde, Susanne; Whale, Graham; Wheeler, James R; Winter, Matthew J

2013-12-01

Tests with vertebrates are an integral part of environmental hazard identification and risk assessment of chemicals, plant protection products, pharmaceuticals, biocides, feed additives and effluents. These tests raise ethical and economic concerns and are considered as inappropriate for assessing all of the substances and effluents that require regulatory testing. Hence, there is a strong demand for replacement, reduction and refinement strategies and methods. However, until now alternative approaches have only rarely been used in regulatory settings. This review provides an overview on current regulations of chemicals and the requirements for animal tests in environmental hazard and risk assessment. It aims to highlight the potential areas for alternative approaches in environmental hazard identification and risk assessment. Perspectives and limitations of alternative approaches to animal tests using vertebrates in environmental toxicology, i.e. mainly fish and amphibians, are discussed. Free access to existing (proprietary) animal test data, availability of validated alternative methods and a practical implementation of conceptual approaches such as the Adverse Outcome Pathways and Integrated Testing Strategies were identified as major requirements towards the successful development and implementation of alternative approaches. Although this article focusses on European regulations, its considerations and conclusions are of global relevance. Copyright © 2013 Elsevier Inc. All rights reserved.

Relative Hazard Calculation Methodology

International Nuclear Information System (INIS)

DL Strenge; MK White; RD Stenner; WB Andrews

1999-01-01

The methodology presented in this document was developed to provide a means of calculating the RH ratios to use in developing useful graphic illustrations. The RH equation, as presented in this methodology, is primarily a collection of key factors relevant to understanding the hazards and risks associated with projected risk management activities. The RH equation has the potential for much broader application than generating risk profiles. For example, it can be used to compare one risk management activity with another, instead of just comparing it to a fixed baseline as was done for the risk profiles. If the appropriate source term data are available, it could be used in its non-ratio form to estimate absolute values of the associated hazards. These estimated values of hazard could then be examined to help understand which risk management activities are addressing the higher hazard conditions at a site. Graphics could be generated from these absolute hazard values to compare high-hazard conditions. If the RH equation is used in this manner, care must be taken to specifically define and qualify the estimated absolute hazard values (e.g., identify which factors were considered and which ones tended to drive the hazard estimation)

National substance use patterns on Twitter.

Directory of Open Access Journals (Sweden)

Hsien-Wen Meng

Full Text Available We examined openly shared substance-related tweets to estimate prevalent sentiment around substance use and identify popular substance use activities. Additionally, we investigated associations between substance-related tweets and business characteristics and demographics at the zip code level.A total of 79,848,992 tweets were collected from 48 states in the continental United States from April 2015-March 2016 through the Twitter API, of which 688,757 were identified as being related to substance use. We implemented a machine learning algorithm (maximum entropy text classifier to estimate sentiment score for each tweet. Zip code level summaries of substance use tweets were created and merged with the 2013 Zip Code Business Patterns and 2010 US Census Data.Quality control analyses with a random subset of tweets yielded excellent agreement rates between computer generated and manually generated labels: 97%, 88%, 86%, 75% for underage engagement in substance use, alcohol, drug, and smoking tweets, respectively. Overall, 34.1% of all substance-related tweets were classified as happy. Alcohol was the most frequently tweeted substance, followed by marijuana. Regression results suggested more convenience stores in a zip code were associated with higher percentages of tweets about alcohol. Larger zip code population size and higher percentages of African Americans and Hispanics were associated with fewer tweets about substance use and underage engagement. Zip code economic disadvantage was associated with fewer alcohol tweets but more drug tweets.The patterns in substance use mentions on Twitter differ by zip code economic and demographic characteristics. Online discussions have great potential to glorify and normalize risky behaviors. Health promotion and underage substance prevention efforts may include interactive social media campaigns to counter the social modeling of risky behaviors.